Propylene glycol methyl ether is an organic solvent with a wide variety of industrial and commercial uses.
Similar to other glycol ethers, Propylene glycol methyl ether is used as a carrier/solvent in printing/writing inks and paints/coatings.
Propylene glycol methyl ether also finds use as an industrial and commercial paint stripper.

CAS: 107-98-2
MF: C4H10O2
MW: 90.12
EINECS: 203-539-1

Propylene glycol methyl ether is used as an antifreeze in diesel engines.
Propylene glycol methyl ether, a glycol ether, can be synthesized by reacting propylene oxide with methanol in the presence of ZnMgAl (zinc-magnesium-aluminium) catalysts.
Propylene glycol methyl ether's degradation by microorganisms in different soil types has been investigated.
Propylene glycol methyl ether is the fastest evaporating solvent of the glycol ether family.

Propylene glycol methyl ether has a high water solubility, excellent solvent with good coupling properties making it suitable for cleaning solutions and coating applications.
This hydrophilic solvent has 100% water solubility and is ideally suited as a coupling agent in a wide range of solvent systems.
Propylene glycol methyl ether appears as a colorless liquid. Flash point near 89 °F.
Less dense than water.
Contact irritates skin, eyes and mucous membranes.
Prolonged exposure to vapors may cause coughing, shortness of breath, dizziness and intoxication.

Vapors heavier than air.
Used as a solvent and as an antifreeze agent.
A colorless liquid.
Flash point near 89°F.
Less dense than water.
Contact irritates skin, eyes and mucous membranes.
Prolonged exposure to vapors may cause coughing, shortness of breath, dizziness and intoxication.
Vapors heavier than air.
Used as a solvent and as an antifreeze agent.

Propylene glycol methyl ether Chemical Properties
Melting point: -97 °C
Boiling point: 118-119 °C(lit.)
density: 0.922 g/mL at 25 °C(lit.)
vapor density: 3.12 (vs air)
vapor pressure: 10.9 mm Hg ( 25 °C)
refractive index: n20/D 1.403(lit.)
Fp: 93 °F
storage temp.: Store at +2°C to +25°C.
solubility water: miscible
form: Liquid
pka: 14.49±0.20(Predicted)
color: Colorless
PH: 4-7 (200g/l, H2O, 20℃)
Odor: sweet ether-like odor
explosive limit: 1.7-11.5%(V)
Water Solubility: soluble
Sensitive: Hygroscopic
BRN: 1731270
Exposure limits: TLV-TWA 100 ppm (370 mg/m3) (ACGIH); STEL 150 ppm (555 mg/m3) (ACGIH).
Stability: Stable. Highly flammable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, water. Moisture-sensitive.
InChIKey: ARXJGSRGQADJSQ-UHFFFAOYSA-N
LogP: 0.37 at 20℃
CAS DataBase Reference: 107-98-2(CAS DataBase Reference)
NIST Chemistry Reference: Propylene glycol methyl ether (107-98-2)
EPA Substance Registry System: Propylene glycol methyl ether (107-98-2)

Propylene glycol methyl ether is a colorless liquid with a sweet ether-like odor and bitter taste.
Propylene glycol methyl ether is soluble in water, ether, acetone, and benzene.

Uses
Propylene glycol methyl ether is primarily used in the manufacture of lacquers and paints, as an anti-freeze in industrial engines, a tailing agent for inks used on very high-speed presses, a coupling agent for resins and dyes in waterbased inks, and a solvent for celluloses, acrylics, dyes, inks, and stains.
Propylene glycol methyl ether is also used in cleaning products such as glass and rug cleaners, carbon and grease removers, and paint and varnish removers; and in pesticide formulations as a solvent for applications to crops and animals.
Propylene glycol methyl ether is used as a solvent for cellulose, acrylics, dyes, inks, and cellophane.
Propylene glycol methyl ether acts as a good biological indicator.

Propylene glycol methyl ether is mainly used as solvent, dispersant and diluent, as well as fuel antifreeze, extractant, etc.
Used as solvent of nitrocellulose, compounding agent of brake oil and detergent, etc. Widely used in coatings and cleaners.
Propylene glycol methyl ether can be used as the active solvent of water-based coatings; Active solvent and coupling agent of solvent based printing ink; Solvent for ballpoint pens and pens; Coupling agents and solvents for household and industrial cleaners, derusting agents and hard surface cleaners; Solvents for agricultural pesticides; Mixed with propylene glycol n-butyl ether for glass cleaner formula.
A glycol ether and a good biological indicator of exposure.

Reactivity Profile
Propylene glycol methyl ether is a methoxy alcohol derivative.
The ether being relatively unreactive.
Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents.
They react with oxoacids and carboxylic acids to form esters plus water.
Oxidizing agents convert them to aldehydes or ketones.
Alcohols exhibit both weak acid and weak base behavior.
They may initiate the polymerization of isocyanates and epoxides.

Health Hazard
Propylene glycol methyl ether is a mild toxicant.
The toxicity is lower than that of the methyl, ethyl, and butyl ethers of ethylene glycol.
The toxic symptoms from inhaling high concentrations are nausea, vomiting, and general anesthetic effects.
In humans, toxic effects may be felt at exposure to a level of 3000–4000 ppm.
The oral and dermal toxicities in test animals were low.
The effects were mild depression of the central nervous system and a slight change in liver and kidney.

Synthesis
Propylene glycol methyl ether is used as a reagent in the synthesis of 2-amino-3-carboxy-4-phenylthiophenes, which acts as a protein kinase C inhibitors.
Propylene glycol methyl ether is also used as a reagent in the synthesis of metolachlor.

Synonyms
1-Methoxy-2-propanol
107-98-2
1-Methoxypropan-2-ol
Methoxyisopropanol
PGME
2-Propanol, 1-methoxy-
Closol
Propylene glycol monomethyl ether
Dowtherm 209
1-Methoxy-2-hydroxypropane
Propasol solvent M
Dowanol 33B
PROPYLENE GLYCOL METHYL ETHER
2-Methoxy-1-methylethanol
Methyl proxitol
2-Propanol, methoxy-
Propylene glycol 1-methyl ether
Ucar Solvent LM (Obs.)
NSC 2409
Dowanol-33B
HSDB 1016
1-methoxy-propan-2-ol
EINECS 203-539-1
UN3092
BRN 1731270
UNII-74Z7JO8V3U
.alpha.-Propylene glycol monomethyl ether
AI3-15573
74Z7JO8V3U
Propyleneglycol monomethyl ether
DTXSID8024284
NSC-2409
EC 203-539-1
3-01-00-02146 (Beilstein Handbook Reference)
DTXCID804284
CAS-107-98-2
propyleneglycol monomethylether
Glycol ether pm
Ucar solvent lm
Solvent PM
Icinol PM
methoxy isopropanol
Methoxy-2-propanol
MFCD00004537
1-methoxypropanol-2
1-Metoxipropan-2-ol
1-Metoksy-2-propanol
PME (CHRIS Code)
3-methoxy-propan-2-ol
Propan-1-methoxy-2-ol
2-Propanol, 1-metoxi-
rac-1-methoxy-2-propanol
1- methoxypropan- 2- ol
1,2-PROPYLENE GLYCOL 1-MONOMETHYL ETHER
2-methoxy-1-methyl ethanol
Propan-2-ol, 1-methoxy-
propylene glycol monomethylether
1-Methoxy-2-propanol, 98%
1-Methoxy-2-propanol (PGME)
Methoxypropanol, .alpha. isomer
(+/-)-1-methoxy-2-propanol
1 - methoxypropan - 2 - ol
CHEMBL3186306
METHOXYISOPROPANOL [INCI]
NSC2409
WLN: QY1 & 1O1
propylene glycol mono methyl ether
(+/-)2-methoxy-1-methylethanol
Propylene Glycol 1-Monomethyl Ether
Tox21_201803
Tox21_303269
LS-444
NA3092
1-Methoxy-2-propanol, >=99.5%
AKOS009158246
SB44649
SB44662
NCGC00249123-01
NCGC00256978-01
NCGC00259352-01
Propylene glycol monomethyl ether (PGME)
1-METHOXY-2-HYDROXYPROPANE [HSDB]
1-Methoxy-2-propanol, analytical standard
FT-0608005
FT-0647598
FT-0654880
FT-0655258
M0126
EN300-73396
E72455
PROPYLENE GLYCOL MONOMETHYL ETHER, ALPHA
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
Q1884806
VOC Mixture 614 1.3-930 microg/mL in Triacetin
1-Methoxy-2-propanol [UN3092] [Flammable liquid]
VOC Mixture Kit 664 0.15-930 microg/mL in Triacetin
Z825742124
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
Propylene glycol monomethyl ether; (UCAR TRIOL HG-170)
InChI=1/C4H10O2/c1-4(5)3-6-2/h4-5H,3H2,1-2H