Polyaminopropyl Biguanide (PHMB) consists of propyl biguanide units.
Polyaminopropyl Biguanide (PHMB) comes as a solid powder/liquid.
CAS Number: 32289-58-0 / 70170-61-5 / 133029-32-0 / 28757-47-3
Chem/IUPAC Name: Homopolymer of N-(3-Aminopropyl)-Imidodicarbonimidic Diamide
Chemical formula: (C5H11N5)n
SYNONYMS:
Polyamine-propyl-biguanidine, Polyaminopropyl Biguanide, Polyhexamethylene biguanide hydrochloride (PHMB HCl), Polyaminopropyl Biguanide, Polyhexanide, Polyhexamethylenebiguanide (PHMB), IMIDODICARBONIMIDIC DIAMIDE, N-(3-AMINOPROPYL)- HOMOPOLYMER, N-(3-AMINOPROPYL)- HOMOPOLYMER IMIDODICARBONIMIDIC DIAMIDE, and POLYAMINOPROPYL BIGUANIDE,
Polyaminopropyl Biguanide (PHMB) is a broad-spectrum antimicrobial compound found in contact lens cleaning solutions, skin disinfection treatments, and wound dressings, among other things.
Polyaminopropyl Biguanide (PHMB) is an aqueous-based cationic preservative, active against spoilage bacteria and is compatible with a wide range of aqueous based cosmetics and personal care formulations.
Its gentle nature makes Polyaminopropyl Biguanide (PHMB) ideal for both rinse-off and leave-on applications like shampoo (with cationic, nonionic or amphoteric surfactants), hair care products, skin creams, skin lotions, baby products, and wet wipes.
When mildness is an important feature for your product, Polyaminopropyl Biguanide (PHMB)'s gentle and protective nature could make it your solution.
Polyaminopropyl Biguanide (PHMB), also known as PAPB or PHMB (Polyhexamethyl biguanide), is a synthetic polymer.
Polyaminopropyl Biguanide (PHMB) consists of propyl biguanide units.
Polyaminopropyl Biguanide (PHMB) comes as a solid powder/liquid (20% aqueous solution).
Polyaminopropyl Biguanide (PHMB) acts as an aqueous-based cationic preservative, active against spoilage bacteria.
Polyaminopropyl Biguanide (PHMB) is compatible with a wide range of aqueous based cosmetics and personal care formulations.
Polyaminopropyl Biguanide (PHMB) is a polymer used as a disinfectant and antiseptic.
Polyaminopropyl Biguanide (PHMB) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.
Occurrence of Polyaminopropyl Biguanide (PHMB) in cosmetics: As a preservative in various cosmetic products – except for sprayable (inhalable) formulations
Polyaminopropyl Biguanide (PHMB) is a Formaldehyde free, Halogen free, Paraben free, aqueous-based cationic preservative, active against spoilage bacteria.
Polyaminopropyl Biguanide (PHMB)'s gentle nature makes it ideal for both rinse-off and leave-on applications.
Polyaminopropyl Biguanide (PHMB) is available as a 20% water solution.
olyaminopropyl Biguanide (PHMB) is an aqueous-based cationic preservative, active against spoilage bacteria and is compatible with a wide range of aqueous based cosmetics and personal care formulations.
Its gentle nature makes Polyaminopropyl Biguanide (PHMB) ideal for both rinse-off and leave-on applications like shampoo (with cationic, nonionic or amphoteric surfactants), hair care products, skin creams, skin lotions, baby products, and wet wipes.
Polyaminopropyl Biguanide (PHMB) is available as a 20% water solution.
The recommended use level of Polyaminopropyl Biguanide (PHMB) is up to 0.3% active (i.e. 1.5% of the 20%water solution).
Polyaminopropyl Biguanide (PHMB) is incompatible with anionic surfactants and soaps, should be kept at a pH below 8.0 and should not be heated above 80°C.
When mildness is an important feature for your product, Polyaminopropyl Biguanide (PHMB)’s gentle and protective nature could make it your solution.
USES and APPLICATIONS of POLYAMINOPROPYL BIGUANIDE (PHMB):
Polyaminopropyl Biguanide (PHMB) can be used in swimming pools as an alternative to chlorine, for industria water (cooling tower, …),Surface disinfecting, hospitals, algaecide for concrete surfaces, all purpose surfaces disinfectant.
Polyaminopropyl Biguanide (PHMB) is used food industry, such as mink feed preservative, beet sugar disinfectant, precleanning of fresh vegetables, cleaning solution for food contact equipment.
Leather industry use of Polyaminopropyl Biguanide (PHMB): preservation of hides and skins, Vet applications, teat dip mixtures, teat dip cloth, animal blood preservation, veterinary operations, preservative used for vet products.
Cosmetics uses of Polyaminopropyl Biguanide (PHMB): cited in the European Cosmetic directory, contact lens cleaner.
Pharmaceuticals use of Polyaminopropyl Biguanide (PHMB): wound operations disinfectant, active used in nose drop/eyes diseases treatment products.
Other applications of Polyaminopropyl Biguanide (PHMB): preservative used in the paper industry, disinfectant used in the secondary oil recovery.
Polyaminopropyl Biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in several ways including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners.
PHMB is also used in cleansing products such as hand sanitizers.
Polyaminopropyl Biguanide (PHMB) is used as a preservative in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.
In cosmetics, the preservation of fruit and vegetables.
Polyaminopropyl Biguanide (PHMB) is also used to preserve wet wipes; to control odor in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, farm equipment, animal drinking water, and hard surfaces for food handling institutions and hospitals; and to deodorize vacuums and toilets.
Its gentle nature makes Polyaminopropyl Biguanide (PHMB) ideal for both rinse-off and leave-on applications like shampoo (with cationic, nonionic or amphoteric surfactants), hair care products, skin creams, skin lotions, baby products and wet wipes.
Its gentle nature makes Polyaminopropyl Biguanide (PHMB) ideal for both rinse-off and leave-on applications like shampoo (with cationic, nonionic or amphoteric surfactants), hair care products, skin creams, skin lotions, baby products, and wet wipes.
Polyaminopropyl Biguanide (PHMB) is available as a 20% water solution.
The recommended use level of Polyaminopropyl Biguanide (PHMB) is up to 0.3% active (i.e. 1.5% of the 20%water solution).
Polyaminopropyl Biguanide (PHMB) is incompatible with anionic surfactants and soaps, should be kept at a pH below 8.0 and should not be heated above 80°C.
When mildness is an important feature for your product, Polyaminopropyl Biguanide (PHMB)’s gentle and protective nature could make it your solution.
The recommended use level of Polyaminopropyl Biguanide (PHMB) is up to .03% active (1.5% of the 20% water solution).
Personal Care uses of Polyaminopropyl Biguanide (PHMB): Antimicrobial used in shampoo, hair care products, skin cream, lotion and moisturizer, sunscreen and wet wipes
Products containing Polyaminopropyl Biguanide (PHMB) are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.
Polyaminopropyl Biguanide (PHMB) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Polyaminopropyl Biguanide (PHMB) is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.
Polyaminopropyl Biguanide (PHMB) is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Polyaminopropyl Biguanide (PHMB) is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
The Polyaminopropyl Biguanide (PHMB) hydrochloride salt (solution) is used in the majority of formulations.
Polyaminopropyl Biguanide (PHMB) is used as a disinfectant and antiseptic.
Cosmetics uses of Polyaminopropyl Biguanide (PHMB): Antimicrobial used in mascara, eye liner and make-up remover
USAGE AND BENEFITS OF POLYAMINOPROPYL BIGUANIDE (PHMB):
Polyaminopropyl Biguanide (PHMB) is used as a preservative in both rinse-off and leave-on cosmetic products.
Polyaminopropyl Biguanide (PHMB) is beneficial in two ways:
First, Polyaminopropyl Biguanide (PHMB) cleans and sterilizes the skin by neutralizing harmful microorganisms on the skin.
Secondly, Polyaminopropyl Biguanide (PHMB) helps preserve a product throughout its shelf life and use.
The presence of water and other organic substances such as natural extracts in a cosmetic product, as well as increased humidity in the environment, can make Polyaminopropyl Biguanide (PHMB) prone to microbial growth.
Additionally, Polyaminopropyl Biguanide (PHMB) is more likely to be contaminated by a microorganism once it has been opened and put into use.
When such a contaminated product is used on the skin/hair and the skin is not intact, Polyaminopropyl Biguanide (PHMB)'s use may become dangerous as it may cause infection in the skin where it is used.
Polyaminopropyl Biguanide (PHMB) protects the product from spoilage caused by microbial growth by inhibiting the growth of microorganisms.
Polyaminopropyl Biguanide (PHMB) is used in the formulations of hair care products, bath and cleaning products, skin and make-up products.
FUNCTIONS OF POLYAMINOPROPYL BIGUANIDE (PHMB) IN COSMETIC PRODUCTS:
*PRESERVATIVE
Polyaminopropyl Biguanide (PHMB) protects cosmetic products from microbial spoilage
WHAT DOES POLYAMINOPROPYL BIGUANIDE (PHMB) DO IN A FORMULATION?
*Preservative
PHYSICAL and CHEMICAL PROPERTIES of POLYAMINOPROPYL BIGUANIDE (PHMB):
CAS Number: 32289-58-0 / 70170-61-5 / 133029-32-0 / 28757-47-3
Chem/IUPAC Name: Homopolymer of N-(3-Aminopropyl)-Imidodicarbonimidic Diamide
Chemical formula: (C5H11N5)n
FIRST AID MEASURES of POLYAMINOPROPYL BIGUANIDE (PHMB):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available
ACCIDENTAL RELEASE MEASURES of POLYAMINOPROPYL BIGUANIDE (PHMB):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of POLYAMINOPROPYL BIGUANIDE (PHMB):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYAMINOPROPYL BIGUANIDE (PHMB):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of POLYAMINOPROPYL BIGUANIDE (PHMB):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
STABILITY and REACTIVITY of POLYAMINOPROPYL BIGUANIDE (PHMB):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
