Water Treatment, Metal and Mining Chemicals

ZINC CITRATE
ZINC CITRATE PREMIUM FORMULA - Our Zinc citrate Tablets are the made with high quality Zinc Citrate 3rd Part Lab Tested - Our All Best Naturals Products come with 3rd Party Independent Lab Tested Zinc citrate Supplement supports healthy immune function & Supports Enzyme Functions No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Corn, No Soy, No Egg, No Lactose, No Gluten, No Wheat, No Yeast, No Fish TOP QUALITY GMP CERTIFIED PRODUCTS - All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency. Brand Solgar Ingredients Zinc citrate (as zinc citrate) Amt Per Serving:30 mg % Daily Value :200%,,Other Ingredients: Microcrystalline cellulose, vegetable cellulose, vegetable magnesium stearate, vegetable stearic acid. Serving Description 1 Vegetable Capsule Diet Type Gluten Free, Kosher, Vegan Material type free GMO Free, Gluten Free About this item Optimal Absorption; Solgar Zinc Citrate contains the citrate form of Zinc citrate to help promote optimal absorption; The 30 mg of Zinc citrate in this formulation represents 273% of the recommended daily value Immune Support; Zinc citrate exerts antioxidant activity and can support a healthy immune system; It also supports cell growth and DNA formation, as well as normal taste and vision Collagen Support; Zinc citrate contributes to healthy skin, nails, and hair; It plays a role in the synthesis of collagen in bone tissue Non GMO, Gluten Free, And Kosher; Solgar Zinc Citrate Vegetable Capsules are suitable for vegans; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and sweetener The Gold Standard: For over 70 years Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials What Are Zinc citrate Supplements Good For? Benefits and More Types Benefits Dosage Safety & Side Effects Bottom Line If you buy something through a link on this page, we may earn a small commission. How this works. Zinc citrate is an essential micronutrient that is crucial to almost every aspect of your health. It’s second only to iron as the most abundant trace mineral in your body (1Trusted Source). Available in many different forms, Zinc citrate supplements are often used to treat an array of ailments. Research shows that this mineral may enhance immune function, stabilize blood sugar levels, and help keep your skin, eyes, and heart healthy. This article reviews the types, benefits, dosage recommendations, and potential side effects of Zinc citrate supplements. Types of Zinc citrate Supplements When choosing a Zinc citrate supplement, you’ll likely notice that there are many different types available. These various forms of Zinc citrate impact health in distinct ways. Here are a few you might find on the market: Zinc citrate gluconate: As one of the most common over-the-counter forms of Zinc citrate, Zinc citrate gluconate is often used in cold remedies, such as lozenges and nasal sprays (2). Zinc citrate acetate: Like Zinc citrate gluconate, Zinc citrate acetate is often added to cold lozenges to reduce symptoms and speed up the rate of recovery (3Trusted Source). Zinc citrate sulfate: In addition to helping prevent Zinc citrate deficiency, Zinc citrate sulfate has been shown to reduce the severity of acne (4Trusted Source). Zinc citrate picolinate: Some research suggests that your body may absorb this form better than other types of Zinc citrate, including Zinc citrate gluconate and zinc citrate (5Trusted Source). Zinc citrate orotate: This form is bound to orotic acid and one of the most common types of Zinc citrate supplements on the market (6). Zinc citrate: One study showed that this type of Zinc citrate supplement is as well-absorbed as Zinc citrate gluconate but has a less bitter, more appealing taste (7Trusted Source). Because it’s one of the most widely available and cost-effective forms of Zinc citrate, Zinc citrate gluconate can be a good option to help bump up your intake without breaking your bank. However, if you’re able to invest a bit more, Zinc citrate picolinate may be better absorbed. Available in capsule, tablet, and lozenge form, there are plenty of options to get your daily dose of Zinc citrate — regardless of the type you choose. However, keep in mind that nasal sprays containing Zinc citrate have been linked to loss of smell and should be avoided (8Trusted Source, 9Trusted Source). SUMMARY There are several forms of Zinc citrate supplements that impact your health in unique ways. They’re generally available in capsule, tablet, and lozenge form. Zinc citrate -containing nasal sprays should be avoided. Potential Benefits Zinc citrate is vital for many aspects of health and has been associated with a variety of benefits. May Improve Immune Function Many over-the-counter medications and natural remedies feature Zinc citrate due to its ability to boost immune function and fight inflammation. One review of seven studies showed that Zinc citrate lozenges containing 80-92 mg of Zinc citrate may reduce common cold duration by up to 33% (10Trusted Source). Zinc citrate may also act as an antioxidant, helping reduce inflammation and protecting against chronic conditions, such as heart disease, cancer, and diabetes (11Trusted Source, 12Trusted Source). One study in 50 older adults found that taking 45 mg of Zinc citrate gluconate for one year decreased several markers of inflammation and reduced the frequency of infections (13Trusted Source). May Promote Blood Sugar Control Zinc citrate is well known for its role in blood sugar control and insulin secretion. Insulin is the hormone responsible for transporting sugar from your bloodstream to your tissues (14Trusted Source). Some research suggests that Zinc citrate may help keep blood sugar levels steady and improve your body’s sensitivity to insulin. One review reported that Zinc citrate supplements were effective at enhancing both short-term and long-term blood sugar control in people with diabetes (15Trusted Source). Other research shows that Zinc citrate may help reduce insulin resistance, which can improve your body’s ability to use insulin efficiently to maintain normal blood sugar levels (16Trusted Source, 17Trusted Source). Helps Fight Acne Zinc citrate supplements are often used to promote skin health and treat common skin conditions like acne (18Trusted Source). Zinc citrate sulfate has been shown to be especially useful for decreasing symptoms of severe acne (4Trusted Source). A 3-month study in 332 people found that taking 30 mg of elemental Zinc citrate — a term that refers to the actual amount of Zinc citrate found in a supplement — was effective at treating inflammatory acne (19Trusted Source). Zinc citrate supplements are also often favored over other treatment methods as they’re inexpensive, effective, and associated with far fewer side effects (18Trusted Source). May Improve Heart Health Heart disease is a serious problem, accounting for roughly 33% of deaths worldwide (20Trusted Source). Some research shows that taking Zinc citrate may improve several risk factors for heart disease and may even lower triglyceride and cholesterol levels. A review of 24 studies found that Zinc citrate supplements helped decrease levels of total and “bad” LDL cholesterol, as well as blood triglycerides, which could potentially aid in preventing heart disease (21Trusted Source). Additionally, one study in 40 young women showed that higher intakes of Zinc citrate were linked to lower levels of systolic blood pressure (the top number of a reading) (22Trusted Source). However, research evaluating the effects of supplements on blood pressure is limited (22Trusted Source). Other research suggests that low levels of serum Zinc citrate may be associated with a higher risk of coronary heart disease, but findings remain inconclusive (23Trusted Source). Slows Macular Degeneration Macular degeneration is a common eye disease and one of the leading causes of vision loss around the globe (24Trusted Source). Zinc citrate supplements are often used to slow the progression of age-related macular degeneration (AMD) and help protect against vision loss and blindness. One study in 72 people with AMD showed that taking 50 mg of Zinc citrate sulfate daily for three months slowed the progression of the disease (25Trusted Source). Similarly, another review of 10 studies reported that supplementing with Zinc citrate was effective at reducing the risk of progression to advanced macular degeneration (26Trusted Source). However, other studies in the review suggested that Zinc citrate supplements alone may not produce significant vision improvements and should be paired with other treatment options to maximize results (26Trusted Source). SUMMARY Zinc citrate may reduce the duration of cold symptoms, support blood sugar control, improve severe and inflammatory acne, decrease heart disease risk, and slow the progression of macular degeneration. Weight management options have evolved Take our quiz to learn more about techniques and tips that will help you achieve your goals. Dosage How much Zinc citrate you should take per day depends on the type, as each supplement contains a different amount of elemental Zinc citrate. For example, Zinc citrate sulfate consists of about 23% elemental Zinc citrate, so 220 mg of Zinc citrate sulfate would equate to about 50 mg of Zinc citrate (27). This amount is usually listed on the label of your supplement, making it easy to determine how much you should take to meet your daily needs. For adults, the recommended daily dosage is typically 15–30 mg of elemental Zinc citrate (4Trusted Source, 28Trusted Source). Higher doses have been used for treating certain conditions, including acne, diarrhea, and respiratory infections. However, due to the potential side effects associated with excess Zinc citrate consumption, it’s best not to exceed the upper limit of 40 mg per day — unless under medical supervision (27). SUMMARY Different Zinc citrate supplements contain varying concentrations of elemental Zinc citrate. The recommended dosage for daily supplements is 15–30 mg. Safety and Side Effects When used as directed, Zinc citrate supplements can be a safe and effective way to increase your Zinc citrate intake and improve several aspects of your health. However, they have been associated with adverse side effects, including nausea, vomiting, diarrhea, and stomach pain (29, 30Trusted Source). Exceeding 40 mg per day of elemental Zinc citrate can cause flu-like symptoms, such as fever, coughing, headache, and fatigue (31Trusted Source). Zinc citrate can also interfere with your body’s ability to absorb copper, potentially leading to a deficiency in this key mineral over time (32Trusted Source). Furthermore, Zinc citrate supplements have been shown to interfere with the absorption of certain antibiotics, reducing their effectiveness if taken at the same time (27). To reduce your risk of side effects, stick to the recommended dosage and avoid exceeding the tolerable upper limit of 40 mg per day — unless under medical supervision. If you experience any negative side effects after taking Zinc citrate supplements, decrease your dosage and consider consulting with your healthcare professional if symptoms persist. SUMMARY Zinc citrate can cause negative side effects, including digestive issues and flu-like symptoms. It may also interfere with the absorption of copper and reduce the effectiveness of certain antibiotics. Zinc citrate is a mineral essential to many aspects of health. Supplementing with 15–30 mg of elemental Zinc citrate daily may improve immunity, blood sugar levels, and eye, heart, and skin health. Be sure not to exceed the upper limit of 40 mg. Zinc citrate’s side effects include digestive issues, flu-like symptoms, and reduced copper absorption and antibiotic effectiveness. Zinc citrate supplements are widely available online, at your local health store, or pharmacy. Plus, if you want to try and increase your Zinc citrate intake through your diet, many foods are rich in this mineral, such as nuts, seeds, legumes, meat, seafood, and dairy. ZINC CITRATE 30 MG VEGETABLE CAPSULES WRITE A REVIEW Zinc citrate promotes healthy skin, supports normal taste and vision, and promotes the synthesis of collagen in bone tissue.* It also supports cell growth and DNA formation.* It exerts antioxidant activity and can support a healthy immune system.* The citrate form of Zinc citrate in this formulation helps to promote optimal absorption.* Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Although the mechanism of action is not completely known, Zinc citrate supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV). Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration. Zinc citrate trihydrate Drug Entry Zinc citrate Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration The water-soluble Zinc citrate salts gluconate, sulfate, and acetate are commonly used as supplements in tablet or syrup form to prevent Zinc citrate deficiency and to treat diarrhea in children in combination with oral rehydration. Zinc citrate is an alternative compound with high Zinc citrate content, slightly soluble in water, which has better sensory properties in syrups but no absorption data in humans. We used the double-isotope tracer method with 67Zn and 70Zn to measure Zinc citrate absorption from zinc citrate given as supplements containing 10 mg of Zinc citrate to 15 healthy adults without food and compared absorption with that from Zinc citrate gluconate and Zinc citrate oxide (insoluble in water) using a randomized, double-masked, 3-way crossover design. Median (IQR) fractional absorption of Zinc citrate from zinc citrate was 61.3% (56.6–71.0) and was not different from that from Zinc citrate gluconate with 60.9% (50.6–71.7). Absorption from Zinc citrate oxide at 49.9% (40.9–57.7) was significantly lower than from both other supplements (P < 0.01). Three participants had little or no absorption from Zinc citrate oxide. We conclude that zinc citrate, given as a supplement without food, is as well absorbed by healthy adults as Zinc citrate gluconate and may thus be a useful alternative for preventing Zinc citrate deficiency and treating diarrhea. The more insoluble Zinc citrate oxide is less well absorbed when given as a supplement without food and may be minimally absorbed by some individuals. This trial was registered at clinicaltrials.gov as NCT01576627. Go to: Introduction Zinc citrate is an essential trace element that has a critical role in maintaining structural and catalytic functions of >200 enzymes involved in major metabolic pathways, including nucleic acid metabolism, protein synthesis, and cell division (1). Although it remains difficult to define Zinc citrate status, Zinc citrate deficiency appears to be common among children in many developing countries, negatively affecting physical growth, immune competence, neural development, and reproductive outcomes, and increasing morbidity and mortality (2). The WHO considers Zinc citrate deficiency to be a major contributor to the burden of disease in developing countries, especially in those with a high mortality rate (3). Several factors contribute to the development of Zinc citrate deficiency, including increased requirements at certain stages of the life cycle, malabsorption, impaired utilization, and increased losses attributable to repeated diarrhea. However, most often the primary cause of Zinc citrate deficiency is inadequate dietary Zinc citrate intake and low bioavailability of Zinc citrate attributable to the consumption of plant-based diets that are high in phytic acid, thus inhibiting Zinc citrate absorption (2). Zinc citrate is lost in greater quantities during diarrhea, and Zinc citrate supplements have been successfully used to treat diarrhea (4). WHO guidelines for the treatment of diarrhea recommend Zinc citrate supplementation in combination with oral rehydration salts solution (5). The WHO recommends the use of the water-soluble compounds Zinc citrate sulfate (23% Zinc citrate), Zinc citrate acetate (30% Zinc citrate), or Zinc citrate gluconate (14% Zinc citrate) in the form of syrups or dispersible tablets for diarrhea management in infants (6). However, Zinc citrate sulfate and Zinc citrate acetate have a strong metallic, bitter, and astringent taste that needs to be masked. Moreover, the low Zinc citrate content of Zinc citrate gluconate makes this compound more expensive. Of the Zinc citrate compounds permitted in the European Union for use as supplements or for food fortification, Zinc citrate sulfate (water soluble, Zinc citrate content of 23%) and Zinc citrate oxide (water insoluble, Zinc citrate content of 80%) are the least expensive and most commonly used (2). An alternative Zinc citrate compound with promising sensory properties is Zinc citrate citrate (Markus Gerhart, Jungbunzlauer Ladenburg, Ladenburg, Germany, personal communication). This compound has a high Zinc citrate content of 31%, is slightly soluble in water, is odorless, and has a relatively low cost (2). However, there are no human absorption data to support the use of zinc citrate. Zinc citrate promotes healthy skin, supports normal taste and vision, and promotes the synthesis of collagen in bone tissue.* It also supports cell growth and DNA formation.* It exerts antioxidant activity and can support a healthy immune system.* The citrate form of Zinc citrate in this formulation helps to promote optimal absorption.* Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Although the mechanism of action is not completely known, Zinc citrate supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV). Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration. Zinc citrate trihydrate Drug Entry Zinc citrate Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration The water-soluble Zinc citrate salts gluconate, sulfate, and acetate are commonly used as supplements in tablet or syrup form to prevent Zinc citrate deficiency and to treat diarrhea in children in combination with oral rehydration. Zinc citrate is an alternative compound with high Zinc citrate content, slightly soluble in water, which has better sensory properties in syrups but no absorption data in humans. We used the double-isotope tracer method with 67Zn and 70Zn to measure Zinc citrate absorption from zinc citrate given as supplements containing 10 mg of Zinc citrate to 15 healthy adults without food and compared absorption with that from Zinc citrate gluconate and Zinc citrate oxide (insoluble in water) using a randomized, double-masked, 3-way crossover design. Median (IQR) fractional absorption of Zinc citrate from zinc citrate was 61.3% (56.6–71.0) and was not different from that from Zinc citrate gluconate with 60.9% (50.6–71.7). Absorption from Zinc citrate oxide at 49.9% (40.9–57.7) was significantly lower than from both other supplements (P < 0.01). Three participants had little or no absorption from Zinc citrate oxide. We conclude that zinc citrate, given as a supplement without food, is as well absorbed by healthy adults as Zinc citrate gluconate and may thus be a useful alternative for preventing Zinc citrate deficiency and treating diarrhea. The more insoluble Zinc citrate oxide is less well absorbed when given as a supplement without food and may be minimally absorbed by some individuals. This trial was registered at clinicaltrials.gov as NCT01576627. Go to: Introduction Zinc citrate is an essential trace element that has a critical role in maintaining structural and catalytic functions of >200 enzymes involved in major metabolic pathways, including nucleic acid metabolism, protein synthesis, and cell division (1). Although it remains difficult to define Zinc citrate status, Zinc citrate deficiency appears to be common among children in many developing countries, negatively affecting physical growth, immune competence, neural development, and reproductive outcomes, and increasing morbidity and mortality (2). The WHO considers Zinc citrate deficiency to be a major contributor to the burden of disease in developing countries, especially in those with a high mortality rate (3). Several factors contribute to the development of Zinc citrate deficiency, including increased requirements at certain stages of the life cycle, malabsorption, impaired utilization, and increased losses attributable to repeated diarrhea. However, most often the primary cause of Zinc citrate deficiency is inadequate dietary Zinc citrate intake and low bioavailability of Zinc citrate attributable to the consumption of plant-based diets that are high in phytic acid, thus inhibiting Zinc citrate absorption (2). Zinc citrate is lost in greater quantities during diarrhea, and Zinc citrate supplements have been successfully used to treat diarrhea (4). WHO guidelines for the treatment of diarrhea recommend Zinc citrate supplementation in combination with oral rehydration salts solution (5). The WHO recommends the use of the water-soluble compounds Zinc citrate sulfate (23% Zinc citrate), Zinc citrate acetate (30% Zinc citrate), or Zinc citrate gluconate (14% Zinc citrate) in the form of syrups or dispersible tablets for diarrhea management in infants (6). However, Zinc citrate sulfate and Zinc citrate acetate have a strong metallic, bitter, and astringent taste that needs to be masked. Moreover, the low Zinc citrate content of Zinc citrate gluconate makes this compound more expensive. Of the Zinc citrate compounds permitted in the European Union for use as supplements or for food fortification, Zinc citrate sulfate (water soluble, Zinc citrate content of 23%) and Zinc citrate oxide (water insoluble, Zinc citrate content of 80%) are the least expensive and most commonly used (2). An alternative Zinc citrate compound with promising sensory properties is Zinc citrate citrate (Markus Gerhart, Jungbunzlauer Ladenburg, Ladenburg, Germany, personal communication). This compound has a high Zinc citrate content of 31%, is slightly soluble in water, is odorless, and has a relatively low cost (2). However, there are no human absorption data to support the use of zinc citrate.
ZINC DIBENZYL DITHIOCARBAMATE (ZBED)

Zinc Dibenzyl Dithiocarbamate (ZBED) is a chemical compound with the molecular formula C30H32N2S4Zn.
Recognized by its CAS number 14726-36-4, ZBED is commonly used in rubber processing.
Zinc Dibenzyl Dithiocarbamate (ZBED) has a melting point in the range of 183-188 °C, ensuring stability under elevated temperatures.
With a molecular weight of 614.22 g/mol, ZBED serves as an effective vulcanization accelerator in the rubber industry.

CAS Number: 14726-36-4
EC Number: 238-778-0



APPLICATIONS


Zinc Dibenzyl Dithiocarbamate (ZBED) is commonly used as a vulcanization accelerator in the rubber industry.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a crucial role in the processing of rubber compounds for various applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the production of tires, contributing to their strength and durability.

Zinc Dibenzyl Dithiocarbamate (ZBED) serves as a key ingredient in the formulation of rubber sheets for industrial applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the extrusion process to manufacture rubber profiles, seals, and gaskets.
In latex manufacturing, ZBED acts as a primary accelerator, facilitating the vulcanization of latex products.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the production of rubber hoses, ensuring their resistance to wear and aging.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized conveyor belts, contributing to their robustness.

Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the formulation of rubber compounds for sheeting, providing enhanced properties.
Zinc Dibenzyl Dithiocarbamate (ZBED) is an accelerator in the production of rubberized footwear, ensuring durability and wear resistance.

Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the manufacturing of rubber seals and gaskets for automotive applications.
In the production of industrial rubber components, ZBED enhances resistance to environmental factors.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the synthesis of rubberized rollers for use in printing and processing machinery.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the creation of rubberized components for water treatment and wastewater systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the construction industry, including seals.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the formulation of rubberized diaphragms for pumps and valves.
Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the production of rubberized components for electrical cable insulation.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the formulation of rubberized coatings for corrosion protection in various applications.

Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the production of rubberized components for anti-vibration mounts in machinery.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the fabrication of rubberized components for marine applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized components for agricultural machinery.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for medical devices, ensuring compliance with safety standards.

Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the manufacturing of rubberized components for sporting goods, such as balls and athletic equipment.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the formulation of rubberized products for the aerospace industry, including seals and gaskets.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the creation of rubberized components for the production of conveyor belts in material handling systems.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the production of rubberized components for automotive applications, including engine mounts and suspension parts.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the manufacturing of rubberized components for escalator and elevator systems, ensuring smooth operation.

Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized wheels and casters used in material handling equipment.
In the field of renewable energy, ZBED is used in the fabrication of rubberized components for solar panel installations.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the formulation of rubberized components for air handling systems, including HVAC duct connectors.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the production of rubberized components for oil and gas industry applications, such as seals and gaskets.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the creation of rubberized components for the railway industry, including track pads and seals.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the defense sector, including protective gear and equipment.

In the realm of water infrastructure, ZBED is used in the formulation of rubberized components for water treatment plants.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the production of rubberized components for marine fender systems, providing impact resistance at ports.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the formulation of rubberized components for medical devices, ensuring biocompatibility and safety.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the aerospace industry, including seals and gaskets for aircraft.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the creation of rubberized components for sports equipment, such as bicycle tires and golf grips.

Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the formulation of rubberized components for the construction of inflatable structures.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the production of rubberized components for amusement park rides, ensuring safety and reliability.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the formulation of rubberized components for military applications, such as vehicle tracks and equipment.

Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the mining industry, including conveyor belts and seals.
In the realm of agriculture, ZBED is employed in the fabrication of rubberized components for machinery such as combines and tractors.

Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the creation of rubberized components for the production of conveyor belts in material handling systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the formulation of rubberized components for footwear, ensuring comfort and durability in shoe soles.
Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the manufacturing of rubberized components for inflatable boats, providing durability in marine environments.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the production of rubberized components for the electronics industry, including seals for electronic devices.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized components for the production of inflatable airbags in automotive safety systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the textile industry, including rollers for fabric processing.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the formulation of rubberized components for the production of conveyor belts used in the mining and aggregates industry.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the manufacturing of rubberized components for the production of automotive belts, ensuring reliability and durability.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a crucial role in the formulation of rubber compounds for the production of seals and gaskets used in plumbing applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for roller coasters, providing a combination of strength and flexibility.
In the field of household appliances, ZBED is used in the formulation of rubberized components for various applications, including gaskets for dishwashers.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized components for industrial hoses, ensuring resistance to chemicals and abrasion.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the production of rubberized components for the construction industry, including seals for doors and windows.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the formulation of rubber compounds for the production of durable and weather-resistant roofing materials.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the manufacturing of rubberized components for the production of anti-vibration mounts used in machinery.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the formulation of rubberized components for the production of conveyor belts used in the food processing and packaging industry.
In the realm of leisure and recreation, ZBED is used in the fabrication of rubberized components for playground surfaces, ensuring safety and resilience.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the medical industry, including seals for medical devices and equipment.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the creation of rubberized components for water and wastewater treatment plants, providing chemical resistance.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the formulation of rubberized components for the production of seals and gaskets in marine applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the manufacturing of rubberized components for the production of belts and pulleys used in mechanical power transmission systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the formulation of rubberized components for the production of inflatable structures used in temporary shelters and events.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the production of rubberized components for the agricultural industry, including conveyor belts for grain handling.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the formulation of rubberized components for the production of seals and gaskets used in industrial machinery.

Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the manufacturing of rubberized components for the production of vibration isolation mounts used in electronic equipment.
Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the formulation of rubberized components for the production of conveyor belts used in the mining and aggregates industry.

Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the creation of rubberized components for the production of belts and hoses used in air handling and HVAC systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the formulation of rubber compounds for the production of durable and slip-resistant surfaces for sports and recreational facilities.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the oil and gas industry, including seals for pipeline systems.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the manufacturing of rubberized components for the production of conveyor belts used in material handling systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the formulation of rubberized components for the production of inflatable structures used in the aerospace industry.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the creation of rubberized components for the automotive industry, including rubber seals for doors and windows.



DESCRIPTION


Zinc Dibenzyl Dithiocarbamate (ZBED) is a chemical compound with the molecular formula C30H32N2S4Zn.
Recognized by its CAS number 14726-36-4, ZBED is commonly used in rubber processing.

Zinc Dibenzyl Dithiocarbamate (ZBED) has a melting point in the range of 183-188 °C, ensuring stability under elevated temperatures.
With a molecular weight of 614.22 g/mol, ZBED serves as an effective vulcanization accelerator in the rubber industry.
Zinc Dibenzyl Dithiocarbamate (ZBED)'s low solubility in rubbers such as NR, SBR, IIR, and EPDM makes it suitable for various applications.

Zinc Dibenzyl Dithiocarbamate (ZBED) is often utilized as a safe-processing secondary accelerator, enhancing the vulcanization process.
As a primary accelerator in latex, ZBED contributes to the production of latex goods with improved properties.

Zinc Dibenzyl Dithiocarbamate (ZBED) is known for its high resistance to hydrolysis, imparting durability to rubber products.
Zinc Dibenzyl Dithiocarbamate (ZBED) exhibits fast acceleration at higher vulcanization temperatures, making it versatile in rubber manufacturing.
Zinc Dibenzyl Dithiocarbamate (ZBED) is recognized for its low nitrosamine potential, a desirable characteristic in rubber processing.

In rubber sheeting, extrusions, and latex products, ZBED showcases its versatility in different manufacturing processes.
Supplied as a 100% powder in 20kg bags, ZBED is convenient to handle and incorporate into rubber formulations.
Zinc Dibenzyl Dithiocarbamate (ZBED)'s density of 1.42 g/cm³ at 20℃ influences its physical characteristics and behavior in rubber compounds.

Zinc Dibenzyl Dithiocarbamate (ZBED)'s minimal water solubility of 2.3μg/L at 20℃ contributes to its stability in wet conditions.
In its powdered form, ZBED is visually identified as a white to off-white substance, aiding in industrial applications.
With a vapor pressure of 0.001 Pa at 25℃, ZBED demonstrates low volatility, ensuring safe handling.

Zinc Dibenzyl Dithiocarbamate (ZBED)'s solubility of 44.7 mg/L in organic solvents at 20 ℃ enhances its compatibility in rubber processing.
With a LogP value of 4.29 at 20℃, ZBED's partitioning behavior is influenced by its chemical properties.
Beyond its role in rubber processing, ZBED is an analytical tool for detecting copper in plant and biological tissues.

Zinc Dibenzyl Dithiocarbamate (ZBED) has found application in preparing dithiocarbamate ligands, contributing to gold nanoparticle stabilization.
Supplied in a 70% dispersion in an EPR polymeric binder, ZBED ensures ease of handling and dispersion in rubber formulations.

Acting as a non-discoloring and non-staining accelerator, Zinc Dibenzyl Dithiocarbamate (ZBED) maintains the quality and aesthetics of rubber products.
Zinc Dibenzyl Dithiocarbamate (ZBED) serves as an accelerator for latex dispersions and cements, optimizing the vulcanization process in rubber manufacturing.
The polymer-bound dispersion of Zinc Dibenzyl Dithiocarbamate (ZBED) enhances plant safety and quality, providing better uniformity of mix at low temperatures during processing.



PROPERTIES


Chemical Formula: C30H32N2S4Zn
CAS Registry Number: 14726-36-4
CBNumber: CB1110519
Molecular Weight: 614.22 g/mol
MDL Number: MFCD00014470
Melting Point: 183-188 °C
Boiling Point: 330°C (at 101 325 Pa)
Density: 1.42 g/cm³ (at 20°C)
Vapor Pressure: 0.001 Pa at 25°C
Solubility: Moderately soluble in benzene and ethylene dichloride; insoluble in acetone, gasoline, and water
Appearance: White to off-white powder
Color: White to off-white
Water Solubility: 2.3μg/L at 20°C
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
LogP: 4.29 at 20°C
Form: Powder
Odor: Not specified
Chemical Structure: Dithiocarbamate ligand with benzyl groups and a zinc atom.
Applications: Rubber vulcanization accelerator, analytical tool for copper detection, stabilizer for gold nanoparticles.
Handling Form: Typically supplied as a 100% powder in 20kg bags.
Compatibility: Compatible with various rubber types, including NR, SBR, IIR, and EPDM.



FIRST AID


Inhalation:

Move to Fresh Air:
If inhaled, immediately move the affected person to an area with fresh air.

Seek Medical Attention:
If respiratory irritation or breathing difficulties persist, seek medical attention promptly.


Skin Contact:


Remove Contaminated Clothing:
Take off contaminated clothing, shoes, and accessories immediately.

Wash Skin Thoroughly:
Wash the affected skin area with plenty of soap and water for at least 15 minutes.

Seek Medical Attention:
If irritation, redness, or other symptoms persist, seek medical advice.


Eye Contact:

Flush Eyes:
Rinse eyes with gently flowing water for at least 15 minutes, holding eyelids open to ensure thorough flushing.

Remove Contact Lenses:
If applicable, remove contact lenses during the rinsing process.

Seek Medical Attention:
Seek immediate medical attention if irritation, redness, or other eye-related symptoms persist.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting unless directed to do so by medical personnel.

Seek Medical Attention:
Immediately seek medical attention and provide the affected person with a copy of the product's SDS.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety glasses or goggles, and protective clothing.
Use respiratory protection if the potential for dust or vapors is present.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.

Avoid Contact:
Avoid skin contact and inhalation of dust or vapors.
Do not eat, drink, or smoke while handling the substance.

Hygiene Practices:
Wash hands and face thoroughly after handling.
Launder contaminated clothing before reuse.

Storage:
Store ZBED in a cool, dry, and well-ventilated area.
Keep away from incompatible materials, such as strong acids, bases, and oxidizing agents.

Storage Containers:
Use appropriate containers made of compatible materials (e.g., stainless steel, polyethylene) to store ZBED.
Ensure containers are tightly sealed to prevent contamination and moisture absorption.

Segregation:
Segregate from incompatible substances to prevent reactions or contamination.

Handling Equipment:
Use dedicated equipment or ensure proper cleaning of shared equipment to prevent cross-contamination.


Storage Conditions:

Temperature:
Store ZBED at temperatures consistent with recommendations to prevent degradation or changes in properties.

Light Exposure:
Store away from direct sunlight or other intense light sources to prevent degradation.

Moisture Control:
Avoid exposure to moisture or humidity to prevent clumping or changes in solubility.

Fire Precautions:
Keep away from ignition sources and avoid storing near combustible materials.
Follow local regulations and guidelines for storing potentially flammable substances.

Labeling:
Clearly label storage areas with proper signage indicating the presence of ZBED and associated hazards.
Keep containers properly labeled with product information.

Emergency Response:
Have appropriate firefighting equipment, spill response materials, and emergency measures in place.

Training:
Ensure that personnel handling and storing ZBED are trained in safe practices and emergency response procedures.

Regulatory Compliance:
Comply with local, regional, and national regulations regarding the storage and handling of hazardous substances.

Periodic Inspection:
Regularly inspect storage areas for leaks, damage, or other conditions that may compromise the integrity of containers.


Emergency Procedures:

Spill Response:
In the event of a spill, follow established spill response procedures outlined in the SDS.
Wear appropriate PPE during cleanup.

Leak Containment:
Contain leaks to prevent the spread of the substance.
Use absorbent materials to control and clean up spills.

Disposal:
Dispose of ZBED in accordance with local regulations and guidelines.
Do not discharge into water sources or sewage systems without proper treatment and permission.



SYNONYMS


ZBDC
ZBEC-70
BENZYL ZIMATE
Accelerator ZBEC (DBZ)
ZINC DIBENZYLDITHIOCARBAMATE
N,N-dibenzylcarbamodithioate
Zinkbis(dibenzyldithiocarbamat)
ZINC N,N-DIBENZYLDITHIOCARBAMATE
Zinc(II) Dibenzyldithiocarbamate
ZBEC
Dibenzylcarbamodithioic acid zinc salt
Dibenzyldithiocarbamic acid zinc salt
Zinc bis(dibenzylcarbamodithioate)
Bis(dibenzylcarbamodithioato-S,S')zinc
Zineb
Benzyl Zimate
N,N-Dibenzyl-N,N-dimethyldithiocarbamate zinc salt
Zimate
Zinc bis(N,N-dibenzylthiocarbamoyl)oxide
Bis(N,N-dibenzylcarbamodithioato)zinc
N,N-Dibenzylcarbamic acid zinc salt
Zinc, bis(carbamodithioato-S,S')dibenzyl-
ZBED-70
Zinc dibenzylcarbamodithioate
Zinc N,N-dibenzyl-N,N-diethyldithiocarbamate
Zinc dibenzylthiocarbamate
Dibenzyldithiocarbamate zinc salt
Zinc dibenzylthiuram disulfide
ZBED Accelerator
Bis(dibenzylcarbamodithioato-S,S') zinc
Zinc bis(N,N-dibenzylcarbamodithioate)
N,N-Dibenzylcarbamic acid zinc salt
Zinc dibenzylcarbamodithiocinate
Zinc bis(dibenzyldithiocarbamoyl)oxide
Zinc N,N-dibenzyl-N,N-diisobutyldithiocarbamate
Dibenzyl(dithiocarbamoylthio)zinc
Zimate ZBED
Zinc bis(N,N-dibenzylcarbamodithioate)
Zinc dibenzylcarbodithioate
Zinc bis(N,N-dibenzylcarbamodithiocinate)
Zinc dibenzyl-N,N-dimethylthiocarbamate
ZBED-75
N,N-dibenzyl-N,N-diisopropyldithiocarbamic acid zinc salt
N,N-dibenzylcarbamodithioic acid zinc salt
Bis(dibenzylcarbamodithioato)zinc oxide
Zinc N,N-dibenzyl-N,N-dipropyldithiocarbamate
Zinc N,N-dibenzyl-N,N-diethyldithiocarbamic acid
N,N-dibenzyl-N,N-dipropyldithiocarbamic acid zinc salt
Zinc bis(dibenzylcarbamodithioato-S,S') oxide
Dibenzyldithiocarbamoyl zinc
Zinc N,N-dibenzyl-N,N-dipropylcarbamodithiocinate
Zinc bis(N,N-dibenzylcarbamodithioato)oxide
N,N-dibenzyl-N,N-diethyldithiocarbamic acid zinc salt
Zinc bis(dibenzyldithiocarbamic acid) oxide
Zinc N,N-dibenzyl-N,N-dipropylthiocarbamate
Zinc dibenzyl-N,N-diethylthiocarbamic acid
Zinc N,N-dibenzyl-N,N-dimethylthiocarbamic acid
Zinc bis(N,N-dibenzylthiocarbamoyl)oxide
Dibenzyl(thiocarbamoylthio)zinc
ZINC DIBENZYLDITHIOCARBAMATE (ZBEC)
Zinc Dibenzyldithiocarbamate (ZBEC) is zinc dibenzyl dithiocarbamate-based vulcanization accelerator.
Zinc Dibenzyldithiocarbamate (ZBEC) is an accelerator for the vulcanization of natural- and synthetic rubbers


CAS Number: 14727-36-4
EC Number: 238-778-0
MDL Number: MFCD00014470
Molecular Formula: C30H28N2S4Zn



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Zinc Dibenzyldithiocarbamate (ZBEC) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Zinc Dibenzyldithiocarbamate (ZBEC) is zinc dibenzyl dithiocarbamate-based vulcanization accelerator.


Zinc Dibenzyldithiocarbamate (ZBEC) is an accelerator for the vulcanization of natural- and synthetic rubbers.
Zinc Dibenzyldithiocarbamate (ZBEC) has a high level of processing safety compared with conventional dithiocarbamate accelerators.
In compounds containing thiazole or sulfenamide accelerators, Zinc Dibenzyldithiocarbamate (ZBEC) has an activating effect.


Zinc Dibenzyldithiocarbamate (ZBEC) contains ethylene propylene diene rubber as a binder.
Zinc Dibenzyldithiocarbamate (ZBEC) is suitable for technical rubber articles based on NR, EPDM, IR, SBR, NBR and IIR.
Zinc Dibenzyldithiocarbamate (ZBEC) is particularly suitable for light or bright-colored rubber articles.


Zinc Dibenzyldithiocarbamate (ZBEC) has a shelf life of 2 years.
Zinc Dibenzyldithiocarbamate (ZBEC) is a very fast primary or secondary accelerator for natural and synthetic rubber.
Zinc Dibenzyldithiocarbamate (ZBEC) is non-staining, non discoloring and is safer processing than ZDBC.


Zinc Dibenzyldithiocarbamate (ZBEC) is also useful as a secondary accelerator for the continuous vulcanization of butyl rubber extrusions.
Zinc Dibenzyldithiocarbamate (ZBEC) has found usefulness in minimizing harmful nitrosoamines.
Nitrosodibenzylamine is not carcinogenic, according to publish literature.


Zinc Dibenzyldithiocarbamate (ZBEC) is a white to grayish white powder boiling point: 408.3 ºC at 760mmHg Melting point: 183-188 °C Flash point: 200.8 C.
Zinc Dibenzyldithiocarbamate (ZBEC) is stable at room temperature in closed containers under normal storage and handling conditions.
Store Zinc Dibenzyldithiocarbamate (ZBEC) in a tightly closed container.


Store Zinc Dibenzyldithiocarbamate (ZBEC) in a cool, dry, Well-ventilated area away from incompatible substances.
Steam pressure of Zinc Dibenzyldithiocarbamate (ZBEC) is 7.06E-07mmHg at 25°C
Zinc Dibenzyldithiocarbamate (ZBEC) is a nonflammable.


Zinc Dibenzyldithiocarbamate (ZBEC) is an accelerator for NR latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is odorless.
Zinc Dibenzyldithiocarbamate (ZBEC) is a dithiocarbamate accelerator for rubber compounds.


Zinc Dibenzyldithiocarbamate (ZBEC) is recognised to have low nitrosamine potential.
Within the range of zinc dithiocarbamates, Zinc Dibenzyldithiocarbamate (ZBEC) provides the longest scorch resistance as well as excellent prevulcanization resistance in latex


Zinc Dibenzyldithiocarbamate (ZBEC) is a white powder (granular).
The relative density of Zinc Dibenzyldithiocarbamate (ZBEC) is 1.14.
The melting point of Zinc Dibenzyldithiocarbamate (ZBEC) is not less than 178 degree.


Zinc Dibenzyldithiocarbamate (ZBEC) is soluble in ethanol, benzene and chloroform, insoluble in water.
Zinc Dibenzyldithiocarbamate (ZBEC) is stable.
Zinc Dibenzyldithiocarbamate (ZBEC) has fast at higher vulcanisation temperatures.



USES and APPLICATIONS of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) is used in formulation or re-packing, at industrial sites and in manufacturing.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in the following products: polymers.
Release to the environment of Zinc Dibenzyldithiocarbamate (ZBEC) can occur from industrial use: formulation in materials.


Zinc Dibenzyldithiocarbamate (ZBEC) is used in the following products: polymers.
Zinc Dibenzyldithiocarbamate (ZBEC) is used for the manufacture of: rubber products, and chemicals.
Release to the environment of Zinc Dibenzyldithiocarbamate (ZBEC) can occur from industrial use: as processing aid and in the production of articles.


Release to the environment of Zinc Dibenzyldithiocarbamate (ZBEC) can occur from industrial use: manufacturing of the substance.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in rubber polymer.
Zinc Dibenzyldithiocarbamate (ZBEC) is used safe-processing secondary accelerator.


Zinc Dibenzyldithiocarbamate (ZBEC) can be used as primary in latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used high resistance to hydrolysis; low solubility in rubbers.
Zinc Dibenzyldithiocarbamate (ZBEC) is used fast at higher vulcanisation temperatures.


Zinc Dibenzyldithiocarbamate (ZBEC) is recognised to have low nitrosamine potential.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in sheeting, extrusions and latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in NR, SBR, IIR and EPDM


Zinc Dibenzyldithiocarbamate (ZBEC)is a useful analytical tool for the detection of copper in plants and biological tissues.
Zinc Dibenzyldithiocarbamate (ZBEC) is also used to prepare dithiocarbamate ligands for stabilizing gold nanoparticles.
Zinc Dibenzyldithiocarbamate (ZBEC) is used accelerator for latex dispersions and cements


Zinc Dibenzyldithiocarbamate (ZBEC) is used ultra-accelerator for NR and synthetic rubbers.
Zinc Dibenzyldithiocarbamate (ZBEC) is often used as a secondary accelerator with
thiazoles.


Zinc Dibenzyldithiocarbamate (ZBEC) has to be used with sulfur and zinc oxide.
Zinc Dibenzyldithiocarbamate (ZBEC) disperses easily in dry rubber. Zinc Dibenzyldithiocarbamate (ZBEC) does not affect latex stability.
In wet rubber, Zinc Dibenzyldithiocarbamate (ZBEC) gives an excellent prevulcanization resistance.


For compounds containing a high level of silica, Zinc Dibenzyldithiocarbamate (ZBEC) improves filler-rubber bound.
Zinc Dibenzyldithiocarbamate (ZBEC) is used non-colouring and non-staining.
General rubber goods use of Zinc Dibenzyldithiocarbamate (ZBEC): latex articles, dispersions, adhesives, wire and cable, extruded sealing profiles, etc.


Zinc Dibenzyldithiocarbamate (ZBEC) is typically used to replace more conventional dithiocarbamates in compounds to reduce or eliminate the generation of potentially hazardous nitrosamines during the vulcanization process.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in sheeting, extrusions and latex. Used in NR, SBR, IIR and EPDM.


Application of Zinc Dibenzyldithiocarbamate (ZBEC): Safe-processing secondary accelerator.
Zinc Dibenzyldithiocarbamate (ZBEC) can be used as primary in latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used high resistance to hydrolysis; low solubility in rubbers.


Zinc Dibenzyldithiocarbamate (ZBEC) is used fast at higher vulcanization temperatures.
Zinc Dibenzyldithiocarbamate (ZBEC) is recognized to have low nitrosamine potential.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in sheeting, extrusions and latex.


Zinc Dibenzyldithiocarbamate (ZBEC) is used in NR, IIR, SBR, and EPDM.
Zinc Dibenzyldithiocarbamate (ZBEC) can be used as primary in latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used high resistance to hydrolysis; low solubility in rubbers.


Zinc Dibenzyldithiocarbamate (ZBEC) has also been used in the preparation of dithiocarbamate ligand for the stabilization of gold nanoparticles.
Zinc Dibenzyldithiocarbamate (ZBEC) uses and applications include: Accelerator, stabilizer for rubber, latex dispersions, cements; accelerator in food-contact rubber articles for repeated use; activator for thiazoles; in food packaging adhesives



Zinc Dibenzyldithiocarbamate (ZBEC) has also been used to prepare dithiocarbamate ligands for the stabilization of gold nanoparticles.
Rubber accelerant, Zinc Dibenzyldithiocarbamate (ZBEC) is only used in the production of cable, tires, hose, tape, bright and transparent products, shoes, electronic products, etc.


Zinc Dibenzyldithiocarbamate (ZBEC) is a useful analytical tool, used in the detection of copper in plant and biological tissues.
Zinc Dibenzyldithiocarbamate (ZBEC) is a useful analytical tool for the detection of copper in plants and biological tissues.
Zinc Dibenzyldithiocarbamate (ZBEC) is used for the manufacture of: rubber products, and chemicals.



SCIENTIFIC RESEARCH APPLICATIONS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
*Copper Determination in High Purity Metals:
Zinc Dibenzyldithiocarbamate (ZBEC)was used for the rapid spectrophotometric determination of copper in high purity metals, offering more sensitivity than the diethyldithiocarbamate method.

*Copper Analysis in Steels:
Employed for the rapid spectrophotometric determination of copper in a wide variety of steels, where Zinc Dibenzyldithiocarbamate (ZBEC)'s acidity range and color stability were advantageous.

*Thermal Decomposition in Rubber Vulcanization:
Investigated for its role in the thermal decomposition of rubber vulcanization, specifically as a precursor for N-nitrosodibenzylamine in processed hams.

*Allergen Testing in Rubber Gloves:
Studied for its role as a vulcanizing agent in rubber gloves and its potential allergenic effects.

*Corrosion Inhibitor for Copper:
Demonstrated as an effective and low-toxicity corrosion inhibitor for copper, forming a hydrophobic film to protect against corrosion.

*Determination of Copper in Dyes and Rubber Chemicals:
Provided a specific method for determining small amounts of copper in rubber chemicals, dyes, and dyed fabrics.

*Copper Determination in Biological Tissues:
Utilized for the direct determination of copper in blood and liver tissues after wet digestion.

*Estimating Copper in Water:
Proven effective in estimating copper in water, showing high accuracy and repeatability.

*Dithiocarbamate Release from Latex Vulcanizates:
Examined for the release of dithiocarbamate accelerators, including Zinc Dibenzyldithiocarbamate (ZBEC), from natural rubber latex vulcanizates.

*Zinc Oxide Nanoparticles in Biomedical Applications:
Related to zinc oxide nanoparticles, these studies explore the application of similar compounds in biomedicine, including their role in anticancer, antibacterial fields, and bioimaging.



MAJOR APPLICATIONS AND PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
- Zinc Dibenzyldithiocarbamate (ZBEC) has been developed as a safe secondary amine dithiocarbamate.
- Zinc Dibenzyldithiocarbamate (ZBEC) is not carcinogenic according to published literature.
- Zinc Dibenzyldithiocarbamate (ZBEC) is used as a primary or secondary ultra-accelerator for thiazole and sulfenamide cure systems for general-purpose polymers (NR, SBR, IIR, EPDM).
Zinc Dibenzyldithiocarbamate (ZBEC) can be used as a primary ultra accelerator in special applications as well as in latex.
- Within the range of zinc dithiocarbamates, Zinc Dibenzyldithiocarbamate (ZBEC) provides the longest scorch resistance as well as excellent prevulcanization resistance in latex.



CHEMICAL PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) is a white powder.
Zinc Dibenzyldithiocarbamate (ZBEC) is moderately soluble in benzene and ethylene dichloride; insoluble in acetone, gasoline, and water.



PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) is white powder (granular).
Zinc Dibenzyldithiocarbamate (ZBEC) is soluble in alcohol, benzene and chloroform, insoluble in water.



SYNTHESIS ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The synthesis of Zinc Dibenzyldithiocarbamate (ZBEC) involves the reaction of zinc oxide with dibenzyldithiocarbamic acid or its salts.
Research into the synthesis of related zinc(II) dithiocarbamate complexes has shown the formation of compounds with varied coordination geometries around zinc, demonstrating the versatility of dithiocarbamate ligands in coordinating with zinc ions to form complexes with distinct molecular structures.



MOLECULAR STRUCTURE ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The molecular structure of Zinc Dibenzyldithiocarbamate (ZBEC) and its complexes has been explored through techniques such as X-ray crystallography, revealing distorted trigonal bipyramidal and tetrahedral coordination geometries around the zinc ion.
These structures highlight the bidentate chelating and bridging capabilities of the dithiocarbamate ligands, which are crucial for the formation of the complexes' molecular architecture.



CHEMICAL REACTIONS AND PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) participates in various chemical reactions due to its active dithiocarbamate group.
Zinc Dibenzyldithiocarbamate (ZBEC) is known for its role in the vulcanization process of rubber, where it acts as an accelerator.
Zinc Dibenzyldithiocarbamate (ZBEC)'s thermal decomposition has been studied, indicating its potential role in nitrosamine formation, which is significant in understanding its behavior under high-temperature conditions associated with rubber processing.



PHYSICAL PROPERTIES ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The physical properties of Zinc Dibenzyldithiocarbamate (ZBEC), such as its thermal stability and solubility in various solvents, are crucial for its application in industrial processes.
Zinc Dibenzyldithiocarbamate (ZBEC)'s thermal decomposition and the stability of its complexes under different conditions have been subjects of research, providing insights into its safe handling and storage requirements.



CHEMICAL PROPERTIES ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The chemical properties of Zinc Dibenzyldithiocarbamate (ZBEC), including its reactivity with other compounds and its role in catalysis, have been explored.
Zinc Dibenzyldithiocarbamate (ZBEC)'s ability to form stable complexes with zinc ions and its reactions under various conditions are essential for understanding its functionality as a vulcanization accelerator and its potential in other chemical processes



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Molecular Weight: 610.2 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 8
Exact Mass: 608.042675 g/mol
Monoisotopic Mass: 608.042675 g/mol
Topological Polar Surface Area: 72.7Ų
Heavy Atom Count: 37
Formal Charge: 0
Complexity: 230
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
CAS No.:14726-36-4
Other Names:Zinc dibenzyl dithiocarbamate
MF:C30H28S4ZnN2
EINECS No.:238-778-0
Purity:99.6% MIN
Type:Dithiocarbamates Rubber Accelerator
Usage:Rubber Auxiliary Agents
Melting point: 183-188 °C
Boiling point: 330℃[at 101 325 Pa]
Density :1.42[at 20℃]
vapor pressure: 0.001Pa at 25℃
solubility: 44.7mg/L in organic solvents at 20 ℃
form: Powder
color: White to off-white

Water Solubility: 2.3μg/L at 20℃
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
LogP: 4.29 at 20℃
Indirect Additives used in Food Contact Substances: ZINC DIBENZYLDITHIOCARBAMATE
FDA 21 CFR: 175.105; 177.2600
CAS DataBase Reference: 14726-36-4(CAS DataBase Reference)
FDA UNII: 33RO266515
EPA Substance Registry System: Zinc dibenzodithiocarbamate (14726-36-4)
Physical Form: Powder
Color: White to cream
Heat Loss (5g, 60°C, 2 hrs): 0.5% Max.
Melting Point: 178°C Min.
CAS No.: 14726-36-4
Molecular Formula: C30H28N2S4Zn
InChIKeys: InChIKey=AUMBZPPBWALQRO-UHFFFAOYSA-L

Molecular Weight: 610.21
Exact Mass: 608.042664
EC Number: 238-778-0
UNII: 33RO266515
HScode: 29302000
PSA: 121.26000
XLogP3: 8.33990
Appearance: White to off-white Powder
Melting Point: 183-188 °C
Boiling Point: 408.3ºC at 760mmHg
Flash Point: 200.8ºC
Storage Conditions: Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure: 7.06E-07mmHg at 25°C
Melting point: 183-188 °C

Boiling point: 330℃[at 101 325 Pa]
density: 1.42[at 20℃]
vapor pressure: 0.001Pa at 25℃
solubility: 44.7mg/L in organic solvents at 20 ℃
form: Powder
color: White to off-white
Water Solubility: 2.3μg/L at 20℃
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
LogP: 4.29 at 20℃
CAS DataBase Reference: 14726-36-4(CAS DataBase Reference)
EPA Substance Registry System: Zinc dibenzodithiocarbamate (14726-36-4)
CAS: 14726-36-4
EINECS: 238-778-0

InChI: InChI=1/C15H15NS2/c17-15(18)16(11-13-7-3-1-4-8-13)12-14-9-5-2-6-10-14/h1-10H,11-12H2,(H,17,18)/p-1
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
Molecular Formula: C30H32N2S4Zn
Molar Mass: 614.22
Density 1.42[at 20℃]
Melting Point: 183-188 °C
Boling Point: 330℃[at 101 325 Pa]
Flash Point: 200.8°C
Water Solubility: 2.3μg/L at 20℃
Solubility: 44.7mg/L in organic solvents at 20 ℃
Vapor Presure: 0.001Pa at 25℃
Appearance: White to white-like powder
Color: White to off-white
Storage Condition: Room Temprature
MDL: MFCD00014470



FIRST AID MEASURES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


ZINC DIBUTYLDITHIOCARBAMATE
Zinc Dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate has a role as an antifungal agrochemical.


CAS Number: 136-23-2
EC Number: 205-232-8
MDL number: MFCD00067274
Molecular Formula: C18H36N2S4Zn



SYNONYMS:
di-n-Butyldithiocarbamic acid,zinc salt, Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-, Zinc, bis(dibutyldithiocarbamato)-, Aceto zdbd, Bis(dibutyldithiocarbamato)zinc, Butazate, Butazate 50-D, Butyl zimate, Butyl ziram, Carbamic acid, dibutyldithio-, zinc complex, Dibutyldithiocarbamic acid zinc salt, USAF GY-5, Vulcacure, Vulkacit ldb/C, Zimate, butyl, Zinc bibutyldithiocarbamate, Zinc N,N-dibutyldithiocarbamate, Accelerator BZ powder, Butasan, Butasan vulcanization accelerator, Butazin, Nocceler BZ, Octocure ZDB-50, Perkacit ZDBC, Soxinol BZ, ZBC, Zinc bis(dibutyldithiocarbamate), Zinc di-n-butyl dithiocarbamate, bis(dibutyldithiocarbamate)zinc(II), Zinc(II) Dibutyl dithiocarbamate, Zinc bis(dibutyldithiocarbamate), Zinc N,N-dibutylcarbamodithioate, Dibutyldithiocarbamic Acid Zinc(II) Salt, carbamate-BZ, ZDBC (BZ), (Dibutyldithiocarbamato)zinc(II), Accel BZ, Aceto ZDBD, Bis(N,N-dibutyldithiocarbamato)zinc, Bis(dibutyldithiocarbamato)zinc, Butazate, Butazate 50-D, Butyl zimate, Butyl ziram, Carbamic acid, dibutyldithio-, zinc complex, Carbamodithioic acid, dibutyl-, zinc salt, Dibutyldithiocarbamic acid zinc salt, Nocceler BZ, Soxinol BZ, Vulcacure, Vulcacure ZB, Vulkacit LDB, Vulkacit LDB/C, Zimate, butyl, Zinc N,N-dibutyldithiocarbamate, Zinc bis(dibutyldithiocarbamate), Zinc dibutyldithiocarbamate, Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-, Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-, Zinc, bis(dibutyldithiocarbamato)-, [ChemIDplus] ZDBC, [HSDB], Zinc N,N-dibutyldithiocarbamate, Butyl zimate, Di-n-butyldithiocarbamic Acid Zinc Salt, Butasan, Butazate, Butazin, Nocceler BZ, Soxinol BZ, ZBC, Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-, Zinc bis(dibutyldithiocarbamate), NSC-3880, ZINC BIS(DIBUTYLDITHIOCARBAMATE), ZINC DIBUTYLDITHIOCARBAMATE, ZINC DIBUTYLDITHIOCARBAMATE [INCI], ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-, ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB], ZINCDIBUTYLD ITHIOCARBAMATE, 2,6-bis(dibutylamino)-1,3,5,7-tetrathia-4-zincaspiro[3.3]hepta-1,5-diene-1,5-bis(ylium), Accelerator BZ powder, Aceto zdbd, Bis(dibutyldithiocarbamato)zinc, Bis(N,N-dibutylthiocarbamoylthio)zinc, Butasan, Butasan vulcanization accelerator, Butazate, Butazate 50-D, Butazin, Butyl zimate, Butyl ziram, Carbamic acid, dibutyldithio-, zinc complex, di-n-Butyldithiocarbamic acid,zinc salt, Dibutyldithiocarbamic acid zinc salt, Nocceler BZ, Octocure ZDB-50, Perkacit ZDBC, Soxinol BZ, Vulcacure, Vulkacit ldb/C, ZBC, Zimate, butyl, Zinc bibutyldithiocarbamate, Zinc di-n-butyl dithiocarbamate, Zinc dibutyldithiocarbamate, Zinc N,N-dibutyldithiocarbamate, Zinc(II) bis(N,N-diisobutyldithiocarbamate), Zinc, bis(dibutylcarbamodithioato-S,S')-, Zinc, bis(dibutyldithiocarbamato)-, USAF GY-5, (T-4)-Bis(dibutylcarbamodithioato-kappas,kappas')zinc, Bis(dibutyldithiocarbamato)zinc, Dibutyldithiocarbamate zinc salt, Zinc bis(dibutyldithiocarbamate), Zinc bis(dibutyldithiocarbamoyl)disulfide, Zinc bis(dibutyldithiocarbamoyl)disulphide, Zinc bis(dibutylthiocarbamoyl)disulfide, Dibutyldithiocarbamic acid zinc salt, Zinc bis(dibutyldithiocarbamic acid), Zinc bis(dibutylthiocarbamoyl)disulphide, Zinc dibutyldithiocarbamic acid, Zinc di-N-butyldithiocarbamic acid, Butasan, Butazate, Butazin, Butyl Zimate, Butyl Ziram, Nocceler BZ, Soxinol, ZBC, ZDBC, Zinc bis(dibutyldithiocarbamate), Zinc N, N-dibutyldithiocarbamate, Butasan, Butazate, Butazin, Butyl Zimate, Nocceler BZ, Soxinol BZ, ZBC, Zinc dibutyldithiocarbamate, Zinc dibutyldithiocarbamate, 136-23-2, Zinc(II) Dibutyldithiocarbamate, Zinc bis(dibutyldithiocarbamate), zinc;N,N-dibutylcarbamodithioate, DTXSID0021462, Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-, DTXCID501462, Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-, CAS-136-23-2, Bis(dibutyldithiocarbamato)zinc, zinc bis(dibutylcarbamodithioate), HNM5J934VP, SCHEMBL35745, dibutyldithiocarbamate zinc salt, ZINCDIBUTYLDITHIOCARBAMATE, CHEMBL2373108, BOXSVZNGTQTENJ-UHFFFAOYSA-L, CHEBI:144323, NSC-3880, Tox21_113038, Tox21_202601, NSC-36548, AKOS015839728, zinc bis(dibutylthiocarbamoyl)disulfide, zinc bis(dibutyldithiocarbamoyl)disulfide, Dibutyldithiocarbamic Acid Zinc(II) Salt, NCGC00188440-01, NCGC00260149-01, zinc bis(dibutyldithiocarbamoyl)disulphide, ZINC DIBUTYLDITHIOCARBAMATE [INCI], CS-0152117, D0227, NS00079390, E81950, ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-, ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB], (T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc, Q27280015, NSC-36548



Zinc Dibutyldithiocarbamate will prevulcanise latex; gives high modulus and transparency.
Zinc Dibutyldithiocarbamate has high solubility in rubbers.
Zinc Dibutyldithiocarbamate is a chemical compound that forms a complex with fatty acids.


Zinc Dibutyldithiocarbamate is found in reaction solutions, where it reacts with hydrochloric acid and boron nitride to form zinc diethyldithiocarbamate.
Zinc Dibutyldithiocarbamate is a vulcanization accelerator for natural rubber and latex and a stabilizer for rubber-based adhesive systems, isobutylene-isoprene copolymers and polypropylene.


Zinc Dibutyldithiocarbamate is used in a number of rubber and rubber-based materials for food packaging and food handling, e.g. conveyor belts.
Zinc Dibutyldithiocarbamate is contact allergens that cross-react in some individuals.
Zinc Dibutyldithiocarbamate, like many low-molecular-weight contact allergens, can only trigger an immune response when bound to a protein in the form of an immunogenic protein–hapten complex.


Haptenation of epidermally relevant skin proteins by Zinc Dibutyldithiocarbamate has not been reported despite the numerous studies on the disposition and systemic toxicity of Zinc dibutyldithiocarbamate.
Zinc Dibutyldithiocarbamate is one of numerous organometallic compounds manufactured.


Organometallics are useful reagents, catalysts, and precursor materials with applications in thin film deposition, industrial chemistry, pharmaceuticals, LED manufacturing, and others.
Zinc Dibutyldithiocarbamate is a white solid with a pleasant odor.


Zinc Dibutyldithiocarbamate is a white to cream-colored powder.
Zinc Dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate has a role as an antifungal agrochemical.


Zinc Dibutyldithiocarbamate is a dermatological sensitizer and allergen.
Sensitivity to Zinc Dibutyldithiocarbamate may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.


Zinc Dibutyldithiocarbamate contains a dibutyldithiocarbamate and a zinc(2+).
Zinc Dibutyldithiocarbamate is functionally related to a dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate is a dermatological sensitizer and allergen.


Sensitivity to Zinc Dibutyldithiocarbamate may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.



USES and APPLICATIONS of ZINC DIBUTYLDITHIOCARBAMATE:
Zinc Dibutyldithiocarbamate is used as an activator and accelerator in natural rubber synthetic latexes.
Zinc Dibutyldithiocarbamate is used Antidegradant, and accelerator, natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, ethylene-propylene-diene terpolymers.


Zinc Dibutyldithiocarbamate is used Antioxidant in rubber-based adhesive.
Zinc Dibutyldithiocarbamate is used condoms and diaphragms.
Zinc Dibutyldithiocarbamate is used cosmetic biocide for skin cleanser and odor prevention.


Zinc Dibutyldithiocarbamate is used gloves (household, work, or hospital).
Zinc Dibutyldithiocarbamate is used heavy rubber products used in industry.
Zinc Dibutyldithiocarbamate is used leather shoes (insoles, adhesives, and linings).


Zinc Dibutyldithiocarbamate is used medical devices.
Zinc Dibutyldithiocarbamate is used renal dialysis equipment.
Zinc Dibutyldithiocarbamate is used rubber in elasticized undergarments and clothing.


Zinc Dibutyldithiocarbamate is used rubber pillows and sheets.
Zinc Dibutyldithiocarbamate is used rubber shoes (sneakers, tennis shoes, and the like).
Zinc Dibutyldithiocarbamate is used sponge makeup applicators and rubber eyelash curlers.


Zinc Dibutyldithiocarbamate is used stabilizer in cement.
Zinc Dibutyldithiocarbamate is used swim wear.
Zinc Dibutyldithiocarbamate is used tires.


Zinc Dibutyldithiocarbamate is used Toys.
Zinc Dibutyldithiocarbamate belongs to the class of organic compounds known as organic transition metal salts.
These are organic salt compounds containing a transition metal atom in its ionic form.


Zinc Dibutyldithiocarbamate is used in Adhesives, Condoms and diaphragms, Disinfectants, repellents, fungicides, and insecticides.
Zinc Dibutyldithiocarbamate is used in agriculture, Gloves (household, work, or hospital), Heavy rubber products used in industry, and Leather shoes (insoles, adhesives, linings).


Zinc Dibutyldithiocarbamate is used medical devices, Renal dialysis equipment, Rubber in elasticized undergarments and clothing, Rubber pillows and sheets, Rubber shoes (sneakers, tennis shoes, etc.), Soaps and shampoos, Sponge makeup applicators and rubber eyelash curlers, Swim wear, and Tires and toys.
Zinc Dibutyldithiocarbamate is used as accelerator (rubber vulcanization, latex dispersions, and cements), ultra-accelerator for lubricating oil additives, and stabilizer in food packaging and handling.


Zinc Dibutyldithiocarbamate is used as an absorbent and sample preparation agent in uv spectroscopy.
Zinc Dibutyldithiocarbamate is used activator, antidegradant and accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethylene-propylene-diene terpolymers. ICU.


Zinc Dibutyldithiocarbamate is a widely used active secondary accelerator for dry rubber.
Zinc Dibutyldithiocarbamate can be used as a primary accelerator in latex.
Zinc Dibutyldithiocarbamate is used in NR, SBR, NBR, IIR, EPDM and latex industry.


Zinc Dibutyldithiocarbamate is used Chemical Synthesis, Plastic, Resin & Rubber, Accelerators, Antioxidants, Polymers, Stabilizer.
Zinc Dibutyldithiocarbamate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Zinc Dibutyldithiocarbamate is used in the following products: coating products and adhesives and sealants.
Other release to the environment of Zinc Dibutyldithiocarbamate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Other release to the environment of Zinc Dibutyldithiocarbamate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Zinc Dibutyldithiocarbamate can be found in products with material based on: rubber (e.g. tyres, shoes, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and wood (e.g. floors, furniture, toys).
Zinc Dibutyldithiocarbamate is used in the following products: coating products.


Zinc Dibutyldithiocarbamate is used in the following areas: building & construction work.
Zinc Dibutyldithiocarbamate is used for the manufacture of: furniture.
Other release to the environment of Zinc Dibutyldithiocarbamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.


Zinc Dibutyldithiocarbamate is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.
Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: formulation of mixtures and formulation in materials.


Zinc Dibutyldithiocarbamate is used in the following products: adhesives and sealants, coating products and fillers, putties, plasters, modelling clay.
Zinc Dibutyldithiocarbamate is used in the following areas: building & construction work.
Zinc Dibutyldithiocarbamate is used for the manufacture of: rubber products, textile, leather or fur and machinery and vehicles.


Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: in processing aids at industrial sites, as processing aid and in the production of articles.
Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: manufacturing of the substance.



WHAT IS ZINC DIBUTYLDITHIOCARBAMATE AND WHERE IS ZINC DIBUTYLDITHIOCARBAMATE FOUND?
Zinc Dibutyldithiocarbamateis used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.
Zinc Dibutyldithiocarbamate is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of Zinc Dibutyldithiocarbamate.



ALTERNATIVE PARENTS OF ZINC DIBUTYLDITHIOCARBAMATE:
*Organosulfur compounds
*Organopnictogen compounds
*Organonitrogen compounds
*Hydrocarbon derivatives



SUBSTITUENTS OF ZINC DIBUTYLDITHIOCARBAMATE:
*Organic transition metal salt
*Organic nitrogen compound
*Organopnictogen compound
*Hydrocarbon derivative
*Organosulfur compound
*Organonitrogen compound
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIBUTYLDITHIOCARBAMATE:
Physical State: Powder
Color: White, off-white
Odor: Not available
Melting Point/Freezing Point:
Melting point/range: 104 - 108 °C
Initial Boiling Point and Boiling Range: 318 °C at 1.013 hPa
Flammability (Solid, Gas): Not available
Upper/Lower Flammability or Explosive Limits: Not available
Flash Point: Not available
Autoignition Temperature: Not available
Decomposition Temperature: Not available
pH: Not available
Viscosity:
Kinematic viscosity: Not available;
Dynamic viscosity: Not available
Water Solubility: 0.1 g/l at 25 °C - Insoluble
Partition Coefficient n-Octanol/Water (log Pow): 2.16 at 25 °C

Vapor Pressure: < 0.1 hPa at 25 °C
Density: 1.24 g/cm3 at 20 °C
Relative Density: Not available
Relative Vapor Density: Not available
Particle Characteristics: Not available
Explosive Properties: Not available
Oxidizing Properties: None
Other Safety Information: Not available
Molecular Weight: 474.1 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 12
Exact Mass: 472.105276 g/mol
Monoisotopic Mass: 472.105276 g/mol
Topological Polar Surface Area: 72.7 Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 112

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Compound Formula: C18H36N2S4Zn
Molecular Weight: 474.12 g/mol
Appearance: White to very pale yellow powder or crystals
Melting Point: 109°C
Boiling Point: Not applicable (N/A)
Density: Not applicable (N/A)
Solubility in H2O: Insoluble
Exact Mass: 472.105 g/mol
Monoisotopic Mass: 472.105 g/mol
Linear Formula: C18H36N2S4Zn

MDL Number: MFCD00067274
EC Number: 205-232-8
PubChem CID: 5284483
IUPAC Name: Zinc; N,N-dibutylcarbamodithioate
SMILES: CCCCNC(CCCC)C(=S)[S-].CCCCNC(CCCC)C(=S)[S-].[Zn+2]
InChI Identifier: InChI=1S/2C9H19NS2.Zn/c21-3-5-7-10(9(11)12)8-6-4-2;/h23-8H2,1-2H3,(H,11,12);/q;;+2/p-2
InChI Key: BOXSVZNGTQTENJ-UHFFFAOYSA-L
Melting Point: 109°C
Color: White-Yellow
Quantity: 25 g
UN Number: 3077
Formula Weight: 474.12
Percent Purity: ≥98.0% (T)
Physical Form: Crystalline Powder

Chemical Name or Material: Zinc(II) Dibutyldithiocarbamate
Appearance: White powder (estimated)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 104.00 °C @ 760.00 mm Hg (estimated)
Flash Point: 32.00 °F TCC (0.00 °C) (estimated)
CAS registration number: 136-23-2
Unique Ingredient Identifier: HNM5J934VP
Molecular formula: 2C9H18NS2.Zn
International Chemical Identifier (InChI): BOXSVZNGTQTENJ-UHFFFAOYSA-L
SMILES: C([S-])(=S)N(CCCC)CCCC.[Zn+2].C([S-])(=S)N(CCCC)CCCC
Formula: C18H36N2S4Zn
InChI: InChI=1S/2C9H19NS2.Zn/c21-3-5-7-10(9(11)12)8-6-4-2;/h23-8H2,1-2H3,(H,11,12);/q;;+4/p-2

InChIKey: UTKYIUWPTCDQSS-UHFFFAOYSA-L
Molecular Weight: 474.122 g/mol
SMILES: C(N(CCCC)C=1S[Zn]2(SC(N(CCCC)CCCC)=[S+]2)[S+]1)CCC
SPLASH: splash10-05fu-9610500000-14d9eea215477cd6b163
Source of Spectrum: JZ-1992-3347-0
Wiley ID: 1393219
Chemical Formula: C18H36N2S4Zn
Average Molecular Mass: 474.120 g/mol
Monoisotopic Mass: 472.105 g/mol
CAS Registry Number: 136-23-2
IUPAC Name: zinc(2+) ion bis((dibutylcarbamothioyl)sulfanide)
Traditional Name: zinc(2+) ion bis((dibutylcarbamothioyl)sulfanide)
SMILES Representation: [Zn++].CCCCN(CCCC)C([S-])=S.CCCCN(CCCC)C([S-])=S
InChI Identifier: InChI=1S/2C9H19NS2.Zn/c21-3-5-7-10(9(11)12)8-6-4-2;/h23-8H2,1-2H3,(H,11,12);/q;;+2/p-2
InChI Key: BOXSVZNGTQTENJ-UHFFFAOYSA-L



FIRST AID MEASURES of ZINC DIBUTYLDITHIOCARBAMATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIBUTYLDITHIOCARBAMATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC DIBUTYLDITHIOCARBAMATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIBUTYLDITHIOCARBAMATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIBUTYLDITHIOCARBAMATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ZINC DIBUTYLDITHIOCARBAMATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC DIBUTYLDITHIOCARBAMATE
Zinc dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc dibutyldithiocarbamate has a role as an antifungal agrochemical.
Zinc dibutyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.

CAS: 136-23-2
MF: C18H36N2S4Zn
MW: 474.14
EINECS: 205-232-8

Synonyms
(dibutyldithiocarbamato)zinc(ii);accelbz;acetozdbd;bis(dibutylcarbamodithioato-S,S’)-,(T-4)-Zinc;vulkacitldb/c;zimate,butyl;zincbibutyldithiocarbamate;Zinc N,N-dibutyldithiocarbamate
Zinc dibutyldithiocarbamate;(Dibutyldithiocarbamato)zinc(II) ; AI3-14880 ; Accel BZ ; Aceto ZDBD ; Bis(N,N-dibutyldithiocarbamato)zinc ; Butazate ; Butazate 50-D ; Butyl zimate ; Butyl ziram ; Carbamic acid, dibutyldithio-, zinc complex ; Carbamodithioic acid, dibutyl-, zinc salt ; Dibutyldithiocarbamic acid zinc salt ; EINECS 205-232-8 ; HSDB 2906 ; NSC 36548 ; NSC 3880 ; Nocceler BZ ; Soxinol BZ ; USAF GY-5 ; Vulcacure ; Vulcacure ZB ; Vulkacit LDB ; Vulkacit ldb/C ; Zimate, butyl ; Zinc N,N-dibutyldithiocarbamate ; Zinc bibutyldithiocarbamate ; Zinc bis(dibutyldithiocarbamate) ; Zinc dibutyldithiocarbamate ; Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)- ; (T-4)-Bis(dibutylcarbamodithioato-S,S')zinc ; Zinc, bis(dibutylcarbamodithioato-S,S')-, (beta-4)- ; Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)- ; Zinc, bis(dibutyldithiocarbamato)-;136-23-2;Zinc(II) Dibutyldithiocarbamate;Zinc bis(dibutyldithiocarbamate);zinc;N,N-dibutylcarbamodithioate;DTXSID0021462;Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-;DTXCID501462;Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-;CAS-136-23-2;Bis(dibutyldithiocarbamato)zinc;zinc bis(dibutylcarbamodithioate);HNM5J934VP;SCHEMBL35745;dibutyldithiocarbamate zinc salt;ZINCDIBUTYLDITHIOCARBAMATE;CHEMBL2373108;CHEBI:144323;NSC-3880;Tox21_113038;Tox21_202601;NSC-36548;AKOS015839728;zinc bis(dibutylthiocarbamoyl)disulfide;zinc bis(dibutyldithiocarbamoyl)disulfide;Dibutyldithiocarbamic Acid Zinc(II) Salt;NCGC00188440-01;NCGC00260149-01;zinc bis(dibutyldithiocarbamoyl)disulphide;ZINC DIBUTYLDITHIOCARBAMATE [INCI];CS-0152117;D0227;FT-0689157;NS00079390;E81950;ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-;ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB];(T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc;Q27280015

Zinc dibutyldithiocarbamate contains a dibutyldithiocarbamate and a zinc(2+).
Zinc dibutyldithiocarbamate is functionally related to a dibutyldithiocarbamic acid.
White powder; pleasant odor.
Soluble in carbon disulfide, benzene, and chloroform; insoluble in water.
A rubber chemical, used as a vulcanization accelerator.
Zinc dibutyldithiocarbamate can also be contained in paints, glue removers, and anticorrosive.
Zinc dibutyldithiocarbamate was contained in “carba-mix.”
Zinc dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.

Zinc dibutyldithiocarbamate has a role as an antifungal agrochemical.
Zinc dibutyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc dibutyldithiocarbamate contains a dibutyldithiocarbamate and a zinc(2+).
Zinc dibutyldithiocarbamate is functionally related to a dibutyldithiocarbamic acid.
Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen.
Sensitivity to Zinc dibutyldithiocarbamate may be identified with a clinical patch test.
Zinc dibutyldithiocarbamate is a chemical compound that forms a complex with fatty acids.
Zinc dibutyldithiocarbamate is used as an absorbent and sample preparation agent in uv spectroscopy.

Zinc dibutyldithiocarbamate can also cause allergic reactions and is toxic to cells in the presence of calcium stearate.
This chemical is found in reaction solutions, where Zinc dibutyldithiocarbamate reacts with hydrochloric acid and boron nitride to form zinc diethyldithiocarbamate.
Zinc dibutyldithiocarbamate has shown growth factor-like properties and was shown to enhance the rate of cell growth on V79 cells when combined with polyene.

Zinc dibutyldithiocarbamate exhibits versatile applications within various fields.
Zinc dibutyldithiocarbamate is particularly useful within the pharmaceutical industry wherein it acts as a catalyst for synthesizing active pharmaceutical ingredients.
Within the polymers industry and rubber manufacturing, Zinc dibutyldithiocarbamate accelerates the production process offering high-quality end-products.
Additionally, Zinc dibutyldithiocarbamate finds usage within miscellaneous chemical syntheses and for industrial applications such as wastewater treatment and gas purification.
Zinc dibutyldithiocarbamate is a chemical compound that is widely used in various industries, including medical, environmental, and industrial research.
Zinc dibutyldithiocarbamate is a white to yellowish powder that is soluble in organic solvents and insoluble in water.
Zinc dibutyldithiocarbamate is a member of the dithiocarbamate family, which is known for its diverse biological activities.
The relative density is 1.18~1.24, and the melting point is above 102 ℃.
Soluble in benzene, carbon disulfide, chloroform, dichloromethane, slightly soluble in gasoline, insoluble in water and dilute alkali.

Zinc dibutyldithiocarbamate Chemical Properties
Melting point: 104-110°C
Boiling point: 318℃[at 101 325 Pa]
Density: 1,21 g/cm3
Vapor pressure: 0Pa at 25℃
Storage temp.: Inert atmosphere,Room Temperature
Solubility: Insoluble in water
Form: solid
Specific Gravity: 1.21
Color: White
Odor: wh. powd., pleasant odor
Water Solubility: 100μg/L at 25℃
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChIKey: BOXSVZNGTQTENJ-UHFFFAOYSA-L
LogP: 2.16 at 25℃
CAS DataBase Reference: 136-23-2(CAS DataBase Reference)
EPA Substance Registry System: Zinc dibutyldithiocarbamate (136-23-2)

Uses
Accelerator for latex dispersions and cements, etc; ultra-accelerator for lubricating oil additive.
Zinc dibutyldithiocarbamate is a rubber chemical used as a vulcanization accelerator.
Zinc dibutyldithiocarbamate can also be found in paints, glue removers and anticorrosives.
Zinc dibutyldithiocarbamate was contained in the "carba-mix".
Zinc dibutyldithiocarbamate is used as activator; antidegradant; accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethyJene-propylene-diene terpolymers.

Preparation
Accelerator bz is prepared by reacting an aqueous solution of an alkali metal salt of di-n-butyl dithiocarbamic acid with an aqueous solution of a water-soluble zinc salt.
Zinc dibutyldithiocarbamate is a vulcanization accelerator for natural rubber and latex.
ZINC DIBUTYLDITHIOCARBAMATE (ZDBC)

Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate (ZDBC) has a role as an antifungal agrochemical.
Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt and a zinc molecular entity.


CAS Number: 136-23-2
EC Number: 205-232-8
MDL number: MFCD00067274
Molecular Formula: C18H36N2S4Zn


Zinc Dibutyldithiocarbamate (ZDBC) (CAS# 136-23-2) is a useful research chemical compound.
Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate (ZDBC) has a role as an antifungal agrochemical.


Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt and a zinc molecular entity.
Zinc Dibutyldithiocarbamate (ZDBC) contains a dibutyldithiocarbamate and a zinc(2+).
Zinc Dibutyldithiocarbamate (ZDBC) is functionally related to a dibutyldithiocarbamic acid.


Zinc Dibutyldithiocarbamate (ZDBC) is a dermatological sensitizer and allergen.
Sensitivity to Zinc Dibutyldithiocarbamate (ZDBC) may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate (ZDBC) is a Standardized Chemical Allergen.


The physiologic effect of Zinc Dibutyldithiocarbamate (ZDBC) is by means of Increased Histamine Release, and Cell-mediated Immunity.
Zinc Dibutyldithiocarbamate (ZDBC) will prevulcanise latex; gives high modulus and transparency.
Zinc Dibutyldithiocarbamate (ZDBC) has high solubility in rubbers.


Zinc Dibutyldithiocarbamate (ZDBC) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Zinc Dibutyldithiocarbamate (ZDBC) is one of numerous organometallic compounds manufactured by American Elements under the trade name AE Organometallics.


Zinc Dibutyldithiocarbamate (ZDBC) contains a dibutyldithiocarbamate and a zinc(2+).
Zinc Dibutyldithiocarbamate (ZDBC) is functionally related to a dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate (ZDBC) is nonflammable.


Zinc Dibutyldithiocarbamate (ZDBC) is a rubber chemical used as a vulcanization accelerator.
Zinc Dibutyldithiocarbamate (ZDBC) can also be found in paints, glue removers and anticorrosives.
Zinc Dibutyldithiocarbamate (ZDBC) was contained in the "carba-mix".


Zinc Dibutyldithiocarbamate (ZDBC) is white solid with a pleasant odor.
Zinc Dibutyldithiocarbamate (ZDBC) is white to cream-colored powder.
Zinc Dibutyldithiocarbamate (ZDBC) is a dermatological sensitizer and allergen.


Sensitivity to Zinc Dibutyldithiocarbamate (ZDBC) may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate (ZDBC) is a dermatological sensitizer and allergen and its formula is C18H36N2S4Zn.
Rubber Accelerator Zinc Dibutyldithiocarbamate (ZDBC) is also known as BZ , White powder(granule).


Zinc Dibutyldithiocarbamate (ZDBC)'s Density is 1.24, soluble in carbon disulfide, benzene, chloroform, ethanol, ether, insoluble in water and dilute alkali.
Zinc Dibutyldithiocarbamate (ZDBC) is stable storage.



USES and APPLICATIONS of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
Zinc Dibutyldithiocarbamate (ZDBC) is used safe-processing secondary accelerator.
Zinc Dibutyldithiocarbamate (ZDBC) can be used as primary in latex.
Zinc Dibutyldithiocarbamate (ZDBC) is used high resistance to hydrolysis; low solubility in rubbers.


Zinc Dibutyldithiocarbamate (ZDBC) is recognized to have low nitrosamine potential.
Zinc Dibutyldithiocarbamate (ZDBC) is used in sheeting, extrusions and latex.
Zinc Dibutyldithiocarbamate (ZDBC) is used in NR, IIR, SBR, and EPDM


Zinc Dibutyldithiocarbamate (ZDBC) is a fast primary or secondary accelerator for NR, SBR, IIR, EPDM and for natural and synthetic latexes mainly in transparent goods and in prevulcanized latex.
Zinc Dibutyldithiocarbamate (ZDBC) is also used as an antioxidant in rubber-based adhesive systems and as a stabilizer in cement.


Zinc Dibutyldithiocarbamate (ZDBC) is used in NR 1 or 2 super accelerator.
IR, BR, SBR, NBR, HR EPDM and Zinc Dibutyldithiocarbamate (ZDBC)'s latex.
Properties are similar to PZ and EZ.


Drying rubber is less effective than PZ and EZ.
Effectively Zinc Dibutyldithiocarbamate (ZDBC) is used in natural and synthetic latex, faster curing and less frosting at room temperature (low temperature) than PZ and EZ.


Zinc Dibutyldithiocarbamate (ZDBC) is a widely used active secondary accelerator for dry rubber.
Zinc Dibutyldithiocarbamate (ZDBC) can be used as a primary accelerator in latex.
Zinc Dibutyldithiocarbamate (ZDBC) is used in NR, SBR, NBR, IIR, EPDM and latex industry.


Zinc Dibutyldithiocarbamate (ZDBC) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: coating products and adhesives and sealants.


Other release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Other release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Zinc Dibutyldithiocarbamate (ZDBC) can be found in products with material based on: rubber (e.g. tyres, shoes, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and wood (e.g. floors, furniture, toys).
Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: coating products.


Zinc Dibutyldithiocarbamate (ZDBC) is used in the following areas: building & construction work.
Zinc Dibutyldithiocarbamate (ZDBC) is used for the manufacture of: furniture.
Other release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.


Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.
Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: formulation of mixtures and formulation in materials.


Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: adhesives and sealants, coating products and fillers, putties, plasters, modelling clay.
Zinc Dibutyldithiocarbamate (ZDBC) is used in the following areas: building & construction work.


Zinc Dibutyldithiocarbamate (ZDBC) is used for the manufacture of: rubber products, textile, leather or fur and machinery and vehicles.
Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: in processing aids at industrial sites, as processing aid and in the production of articles.


Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: manufacturing of the substance.
Zinc Dibutyldithiocarbamate (ZDBC) is used chemical Synthesis, Plastic, Resin & Rubber, Accelerators, Antioxidants, Polymers, Stabilizer.
Zinc Dibutyldithiocarbamate (ZDBC) is used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.


Zinc Dibutyldithiocarbamate (ZDBC) is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of Zinc Dibutyldithiocarbamate (ZDBC).
Zinc Dibutyldithiocarbamate (ZDBC) is a rubber accelerator for natural and synthetic rubber and latex.


Zinc Dibutyldithiocarbamate (ZDBC) can be used up to 1.50 PHR without bloom.
Zinc Dibutyldithiocarbamate (ZDBC) Dispersion is characterised as a fast curing accelerator for use in both Natural and Synthetic latex compounding, with loading levels for sole use being typically 1.0-1.5 parts per hundred dry rubber.


Recommend for use in translucent latex articles and compounds requiring lower modulus than that achieved with ZDEC.
More commonly used in conjuction with ZDEC to form synergtically boosted and more efficient accelerator systems, with the loading level for Zinc Dibutyldithiocarbamate (ZDBC) being usually lower (0.30-0.60phr) than that of the ZDEC (0.4-1.0phr).


Zinc Dibutyldithiocarbamate (ZDBC) is a vulcanization accelerator for natural rubber and latex and a stabilizer for rubber-based adhesive systems, isobutylene-isoprene copolymers and polypropylene.
Zinc Dibutyldithiocarbamate (ZDBC) is used in a number of rubber and rubber-based materials for food packaging and food handling, e.g. conveyor belts.


Zinc Dibutyldithiocarbamate (ZDBC) is contact allergens that cross-react in some individuals.
Zinc Dibutyldithiocarbamate (ZDBC), like many low-molecular-weight contact allergens, can only trigger an immune response when bound to a protein in the form of an immunogenic protein–hapten complex.


Zinc Dibutyldithiocarbamate (ZDBC) is used Accelerator for latex dispersions and cements, etc; ultra-accelerator for lubricating oil additive.
Zinc Dibutyldithiocarbamate (ZDBC) is used as activator; antidegradant; accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethyJene-propylene-diene terpolymers.


Zinc Dibutyldithiocarbamate (ZDBC) is used as accelerator (rubber vulcanization, latex dispersions, and cements), ultra-accelerator for lubricating oil additives, and stabilizer in food packaging and handling.
Zinc Dibutyldithiocarbamate (ZDBC) provides fast cures at low temperatures; slower cure rates than with EZ (ZDEC) or MZ (ZDMC).



PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
White powder (granule).
The density of Zinc Dibutyldithiocarbamate (ZDBC) is 1.24.
Zinc Dibutyldithiocarbamate (ZDBC) is soluble in CS2 benzene, chloroform, alcohol, diethyl ether.
Zinc Dibutyldithiocarbamate (ZDBC) is iinsoluble in water and low concentration alkali.
Zinc Dibutyldithiocarbamate (ZDBC) is good storage stability.



CHEMICAL PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
Zinc Dibutyldithiocarbamate (ZDBC) is white powder.
Zinc Dibutyldithiocarbamate (ZDBC) has pleasant odor.
Zinc Dibutyldithiocarbamate (ZDBC) is soluble in carbon disulfide, benzene, and chloroform.
Zinc Dibutyldithiocarbamate (ZDBC) is insoluble in water.



PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
*Specific gravity:1.30.
*High resistance to hydrolysis;
*Low solubility in rubbers.
*Fast at higher vulca nisation temperatures.



PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
White, pale yellow or offwhite powder, melting point: >103 ºC, density: 1.24, solubility: freely soluble in carbon disulfide, carbon tetrachloride, dichloromethane, benzene, chloroform, soluble in acetone, ethyl acetate, insoluble in water.



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
Molecular Weight: 474.1 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 12
Exact Mass:472.105276 g/mol
Monoisotopic Mass: 472.105276 g/mol
Topological Polar Surface Area: 72.7Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 112
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Physical state: powder
Color: white, off-white
Odor: No data available
Melting point/freezing point:
Melting point/range: 104 - 108 °C
Initial boiling point and boiling range: 318 °C at 1.013 hPa
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility 0,1 g/l at 25 °C
Partition coefficient: n-octanol/water:
log Pow: 2,16 at 25 °C
Bioaccumulation is not expected.
Vapor pressure: < 0,1 hPa at 25 °C
Density: 1,24 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Melting point: 104-110°C
Boiling point: 318℃[at 101 325 Pa]
Density: 1,21 g/cm3
vapor pressure: 0 Pa at 25℃
storage temp.: Inert atmosphere,Room Temperature
solubility: Insoluble in water
form: solid
Specific Gravity: 1.21
color: White
Odor: wh. powd., pleasant odor
Water Solubility: 100μg/L at 25℃
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChIKey: BOXSVZNGTQTENJ-UHFFFAOYSA-L
LogP: 2.16 at 25℃
CAS Number: 136-23-2
Molecular Formula: C₁₈H₃₆N₂S₄Zn
Appearance: White to Off-White Solid
Melting Point: 107 - 109°C
Molecular Weight: 474.12
Storage: 4°C, Inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)

Compound Formula: C18H36N2S4Zn
Molecular Weight: 474.12
Appearance: White to very pale yellow powder or crystals
Melting Point: 109 °C
Boiling Point: N/A
Density: N/A
Solubility in H2O: Insoluble
Exact Mass: 472.105 g/mol
Monoisotopic Mass: 472.105 g/mol
Linear Formula: C18H36N2S4Zn
MDL Number: MFCD00067274
EC No.: 205-232-8
Pubchem CID: 5284483
IUPAC Name: zinc; N,N-dibutylcarbamodithioate
SMILES: CCCCN(CCCC)C(=S)[S-].CCCCN(CCCC)C(=S)[S-].[Zn+2]
InchI Identifier: InChI=1S/2C9H19NS2.Zn/c2*1-3-5-7-10(9(11)12)8-6-4-2;/h2*3-8H2,1-2H3,(H,11,12);/q;;+2/p-2
InchI Key: BOXSVZNGTQTENJ-UHFFFAOYSA-L



FIRST AID MEASURES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Zinc dibutyldithiocarbamate
136-23-2
Zinc(II) Dibutyldithiocarbamate
Zinc bis(dibutyldithiocarbamate)
zinc;N,N-dibutylcarbamodithioate
Bis(dibutyldithiocarbamato)zinc
DTXSID0021462
Vulcacure
Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-
DTXCID501462
Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-
CAS-136-23-2
Butazate
C18H36N2S4Zn
Butyl zimate
Butyl ziram
Vulcacure ZB
Zimate, butyl
Nocceler BZ
Vulkacit ldb/C
zinc bis(dibutylcarbamodithioate)
Soxinol BZ
Vulkacit LDB
Accel BZ
Aceto ZDBD
Butazate 50-D
ZDBC
Zinc bibutyldithiocarbamate
UNII-HNM5J934VP
USAF GY-5
Zinc dibutyl dithiocarbamate
HNM5J934VP
SCHEMBL35745
dibutyldithiocarbamate zinc salt
Zinc N,N-dibutyldithiocarbamate
ZINCDIBUTYLDITHIOCARBAMATE
CHEMBL2373108
(Dibutyldithiocarbamato)zinc(II)
HSDB 2906
CHEBI:144323
Zinc, bis-(dibutyldithiocarbamate)
Bis(N,N-dibutyldithiocarbamato)zinc
Dibutyldithiocarbamic acid zinc salt
NSC 3880
NSC-3880
EINECS 205-232-8
Tox21_113038
Tox21_202601
NSC 36548
NSC-36548
AKOS015839728
zinc bis(dibutylthiocarbamoyl)disulfide
Bis(dibutyldithiocarbamic acid)zinc salt
zinc bis(dibutyldithiocarbamoyl)disulfide
Dibutyldithiocarbamic Acid Zinc(II) Salt
NCGC00188440-01
NCGC00260149-01
zinc bis(dibutyldithiocarbamoyl)disulphide
Carbamodithioic acid, dibutyl-, zinc salt
ZINC DIBUTYLDITHIOCARBAMATE [INCI]
ZINC, BIS(DIBUTYLDITHIOCARBAMATO)-
AI3-14880
CS-0152117
D0227
FT-0689157
E81950
EC 205-232-8
ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-
ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB]
Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-
(T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc
Q27280015
Zinc, bis (dibutilcarbamoditioato-kS, KS')-
(T-4)-
di-n-Butyldithiocarbamic acid,zinc salt
Zinc, bis(dibutylcarbamodithioato-S,S')-
(T-4)-
Zinc, bis(dibutyldithiocarbamato)-
Aceto zdbd
Bis(dibutyldithiocarbamato)zinc
Butazate
Butazate 50-D
Butyl zimate
Butyl ziram
Carbamic acid, dibutyldithio-, zinc complex
Dibutyldithiocarbamic acid zinc salt
USAF GY-5
Vulcacure
Vulkacit ldb/C
Zimate, butyl
Zinc bibutyldithiocarbamate
Zinc N,N-dibutyldithiocarbamate
Accelerator BZ powder
Butasan
Butasan vulcanization accelerator
Butazin
Nocceler BZ
Octocure ZDB-50
Perkacit ZDBC
Soxinol BZ
ZBC
Zinc bis(dibutyldithiocarbamate)
Zinc di-n-butyl dithiocarbamate
bis(dibutyldithiocarbamate)zinc(II)
(Dibutyldithiocarbamato)zinc(II)
Accel BZ
Accelerator BZ
Aceto ZDBD
Antioxidant BZ
BZ
BZ 75
BZ-P
Bis(N,N-dibutyldithiocarbamato)zinc
Bis(dibutyldithiocarbamato)zinc
Butazate
Butazate 50D
Butyl Zimate
Butyl Ziram
Zinc N,N-Dibutyldithiocarbamate
Zinc Bis(Dibutyldithiocarbamate)
ZBC
Zinc(II) Dibutyl dithiocarbamate
Zinc bis(dibutyldithiocarbamate)
Zinc N,N-dibutylcarbamodithioate
Dibutyldithiocarbamic Acid Zinc(II) Salt
carbamate-BZ
ZDBC (BZ)
zbc
accelbz
Nsc3880
butazate
usafgy-5
acetozdbd
soxinolbz
vulcacure
butylziram
noccelerbz
(Dibutyldithiocarbamato)zinc(II)
Accel BZ
Aceto ZDBD
Bis(N,N-dibutyldithiocarbamato)zinc
Bis(dibutyldithiocarbamato)zinc
Butazate
Butazate 50-D
Butyl zimate
Butyl ziram
Carbamic acid, dibutyldithio-, zinc complex
Carbamodithioic acid, dibutyl-, zinc salt
Dibutyldithiocarbamic acid zinc salt
Nocceler BZ
Soxinol BZ
Vulcacure
Vulcacure ZB
Vulkacit LDB
Vulkacit LDB/C
Zimate, butyl
Zinc N,N-dibutyldithiocarbamate
Zinc bis(dibutyldithiocarbamate)
Zinc dibutyldithiocarbamate
Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-
Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-
(T-4)- Zinc, bis(dibutyldithiocarbamato)-
ZDBC
Zinc bis(dibutyldithiocarbamate)
Dibutyldithiocarbamic acid zinc(II) salt
zinc,N,N-dibutylcarbamodithioate
Zinc(II) dibutyldithiocarbamate
Zinc Dibuthyl Dithiocarbamate
NURsol ZDBC
zinc bis(dibutyldithiocarbamate)
accelerator bz
zincbutyldithiocarbamate
zine dibutyl dithiocarbamate
zinc dibutyl dithiocarbamate
zdbc
(dibutyldithiocarbamato)zinc(ii)
accelbz
acetozdbd
bis(dibutylcarbamodithioato-s,s')-,(t-4)-zinc
bis(dibutyldithiocarbamato)-zin
bis(n,n-dibutyldithiocarbamato)zinc
butazate
butazate50-d
butylziram
dibutyl-carbamodithioicacizincsalt
dibutyldithiocarbamicacidzincsalt
dibutyldithio-carbamicacizinccomplex
noccelerbz;s')-bis(dibutylcarbamodithioato-(beta-4)-zin
s')-bis(dibutylcarbamodithioato-(t-4)-zin
soxinolbz
usafgy-5
vulcacure
vulcacurezb
vulcaurezb
Accelerant BZ
N,N-Copper dibuthyldithiocarbamate
zinc bis(dibutylcarbamodithioate)
ACCELERATOR ZDBC
ACCELERATOR ZDBC(BZ)
(T-4)-bis(dibutylcarbamodithioato-κS,κS')zinc
bis(dibutyldithiocarbamato)zinc
dibutyldithiocarbamate zinc salt
zinc bis(dibutyldithiocarbamate)
zinc bis(dibutyldithiocarbamoyl)disulfide
zinc bis(dibutyldithiocarbamoyl)disulphide
zinc bis(dibutylthiocarbamoyl)disulfide
Butasan
Butazate
Butazin
Butyl Zimate
Butyl Ziram
Nocceler BZ
Soxinol
ZBC
ZDBC
Zinc bis(dibutyldithiocarbamate)
Zinc N, N-dibutyldithiocarbamate
Zinc N,N-dibutyldithiocarbamate
Vulcacure ZB
Di-n-butyldithiocarbamic Acid Zinc Salt
Butasan
Butazate
Butazin
Zinc bis(dibutylcarbamodithioato-S,S')-
Zinc bis(dibutyldithiocarbamate)
Butyl zimate
BZ
ZDBC
ZBC

ZINC DIETHYLDITHIOCARBAMATE
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.
Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.


CAS Number: 14324-55-1
EC Number: 238-270-9
MDL number: MFCD00064798
Linear Formula: [(C2H5)2NCS2]2Zn
Molecular Formula : C10H20N2S4Zn



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DTXCID901463, ICW4708Z8G, CHEMBL3182813, zinc bis(diethylcarbamodithioate), CHEBI:144351, RKQOSDAEEGPRER-UHFFFAOYSA-L, Tox21_200263, AKOS030228292, zinc bis(diethylthiocarbamoyl)disulfide, DIETHYLCARBAMIC ACID, ZINC SALT, NSC-177699, zinc bis(diethyldithiocarbamoyl)disulfide, NCGC00257817-01, zinc bis(diethyldithiocarbamoyl)disulphide, CAS-14324-55-1, D0492, FT-0624885, NS00087819, E75979, DIETHYLDITHIOCARBAMIC ACID ZINC SALT [HSDB],
J-007778, (T-4)-bis(diethylcarbamodithioato-kappaS,kappaS')zinc, Q16295596, Zinc bis(diethyldithiocarbamate), Zinc diethylcarbamodithioate, Diethyldithiocarbamic acid zinc salt, zinc diethyldithiocarbamate, ethyl ziram, zinc bis diethyldithiocarbamate, diethyldithiocarbamic acid zinc salt, zinc n,n-diethylcarbamodithioate, ethyl zimate, unii-icw4708z8g, ditiocarb zinc, zdc, zdec, Diethyldithiocarbamic acid zinc salt, Zinc bis(diethyldithiocarbamate), AKOS015914072, Zinc Diethyldithiocarbamate, Zinc diethyldithiocarbamate, 97%, zinc;N,N-diethylcarbamodithioate, Diethyldithiocarbamic acid zinc salt, Accelerator ez powder, Ancazate et, Bis(diethylcarbamodithioato-s,s') zinc, Bis(diethyldithiocarbamato)zinc, Carbamodithioic acid, diethyl-, zinc salt, Diethyldithiocarbamic acid zinc salt, Etazin, Ethasan, Ethazate, Ethyl cymate, Bis(diethyldithiocarbamato)zinc, Carbamodithioic acid, diethyl-, zinc salt, Diethyldithiocarbamic acid zinc salt, Ethazate, Ethyl Ziram, Ethyl cymate, Ethyl zimate, Ethylzimate, Hermat ZDK, Nocceler EZ, Soxinol EZ, Vulcacure ZE, Vulkacit LDA, Vulkacit ZDK, Zimate, ethyl, Zinc N,N-diethyldithiocarbamate, Zinc bis(diethyldithiocarbamate), Zinc diethylcarbamodithioate, Zinc diethyldithiocarbamate (VAN), Zinc, bis(diethylcarbamodithioato-S,S')-, (T-4)-, Zinc, bis(diethyldithiocarbamato), Zinc, tetrakis(diethylcarbamodithioato)di-, Ethasan, Ethazate, Ethazine, Noceller EZ, Soxinol EZ, ZDC, ZDEC, Zinc,bis(N,N-diethylcarbamodithioato-κS,κS′)-,(T-4)-, Zinc,bis(diethyldithiocarbamato)-, Zinc,bis(diethylcarbamodithioato-S,S′)-,(T-4)-, Zinc,bis(diethylcarbamodithioato-κS,κS′)-,(T-4)-, (T-4)-Bis(N,N-diethylcarbamodithioato-κS,κS′)zinc, Zinc diethyldithiocarbamate, Bis(diethyldithiocarbamato)zinc, Zinc bis(diethyldithiocarbamate), Vulkacit ZDK, Zinc diethylcarbamodithioate, Diethyldithiocarbamic acid zinc salt, Ethazate, Ethyl Ziram, Vulcacure ZE, Ethylzimate, Carbamodithioic acid,diethyl-,zinc salt, Hermat ZDK, Vulkacit LDA, Zinc bis(N,N-diethyldithiocarbamate), Zinc N,N-diethyldithiocarbamate, Nocceler EZ, Soxinol EZ, EZ (carbamate), EZ, Bis(diethyldithiocarbamato)zinc(II), Bis(N,N-diethyldithiocarbamato)zinc, NSC 177699, Sanceler EZ, Vulkazit LDA, Perkacit ZDEC-PDR, Karbamat ETS, Accelerator ZDC, ZDC, Accel EZ, ZDEC, Mercure ZDC, Accelerator EZ, Rhenogran ZDEC 80, Accelerator ZDA, Bostex 561, 136-94-7, 14460-21-0, 15465-13-1, 18445-58-4, 32733-02-1, 39456-86-5, 92481-10-2, 115028-55-2, 120092-57-1, 880359-15-9, 905572-85-2, 2169916-09-8, ZDEC, Accelerator EZ, ZINC DIETHYLDITHIOCARBAMATE, RUBBER ACCELERATOR ZDEC(EZ), ZINC N,N-DIETHYLDITHIOCARBAMATE, DIETHYLDITHIOCARBAMIC ACID ZINC SALT



Zinc diethyldithiocarbamate is a dry powder and Liquid.
Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.


Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.
Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).


Zinc diethyldithiocarbamate derives from a diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is a known chelator for copper and zinc.
Zinc diethyldithiocarbamate also a dermatological sensitizer and allergen.


Sensitivity to Zinc diethyldithiocarbamate may be identified with a clinical patch test.
Zinc diethyldithiocarbamate boasts an impressive purity level of 97%, ensuring optimal performance and reliable results in catalytic processes.
Zinc diethyldithiocarbamate is a white to off-white powder, allowing for easy identification and handling during laboratory procedures.


Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.


Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).
Zinc diethyldithiocarbamate is functionally related to a diethyldithiocarbamic acid.


Zinc diethyldithiocarbamate is an inorganic compound that has been shown to have potent anti-inflammatory and antipyretic properties.
Zinc diethyldithiocarbamate has been used as a chemical inhibitor of phospholipase A2, which is an enzyme involved in the inflammatory process.
Zinc diethyldithiocarbamate also has been shown to be a potent inducer of metallothionein and other proteins that are involved in detoxification processes.


Zinc diethyldithiocarbamate is generally immediately available in most volumes.
Zinc diethyldithiocarbamate is high purity, submicron and nanopowder forms may be considered.
Zinc diethyldithiocarbamate is a chemical compound of zinc.


Zinc is a metallic element with the atomic number 30.
It is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc diethyldithiocarbamate belongs to the class of organic compounds known as organosulfur compounds.
These are organic compounds containing a carbon-sulfur bond.
Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.


Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.
Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.


Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).
Zinc diethyldithiocarbamate is functionally related to a diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is a known chelator for copper and zinc.


Sensitivity to Zinc diethyldithiocarbamate may be identified with a clinical patch test.
Zinc diethyldithiocarbamate is a chemical compound of zinc.
Zinc is a metallic element with the atomic number 30.


It is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc diethyldithiocarbamate is used chelating agent that has been used to mobilize toxic metals from the tissues of humans and experimental animals.
Zinc diethyldithiocarbamate is the main metabolite of DISULFIRAM.
Zinc diethyldithiocarbamate, an organo-metallic compound, has found extensive use in scientific and industrial applications over the years.


Zinc diethyldithiocarbamate presents itself as a white powder, soluble in both water and organic solvents, and exhibits strong metal-chelating properties.
Zinc diethyldithiocarbamate serves as a catalyst and reagent in various laboratory reactions and processes.
Within the realm of scientific research, Zinc diethyldithiocarbamate has been harnessed across diverse applications.


Zinc diethyldithiocarbamate has facilitated the study of metal-catalyzed reactions, enabling the synthesis of novel compounds and offering insights into their properties.
Additionally, Zinc diethyldithiocarbamate has been instrumental in exploring biochemical and physiological processes, including the effects of metals on enzyme and protein activity.


The interaction of Zinc diethyldithiocarbamate with metals leads to the formation of chelate complexes.
These complexes subsequently bind to proteins and enzymes, resulting in the inhibition of their activity.
The metal chelation by Zinc diethyldithiocarbamate also exerts additional effects, such as the inhibition of specific biochemical reactions and the modulation of certain enzyme activities.


Zinc diethyldithiocarbamate is used as a common accelerator to latex.
Zinc diethyldithiocarbamate is used a fast curing primary or secondary effective ultra-accelerator for natural and synthetic latex compounds.



USES and APPLICATIONS of ZINC DIETHYLDITHIOCARBAMATE:
Due to its exceptional catalytic properties, Zinc diethyldithiocarbamate finds extensive use in various industries and research laboratories.
Chemical Research uses of Zinc diethyldithiocarbamate: Zinc diethyldithiocarbamate is widely employed as a catalyst in chemical research, enabling scientists to study and develop new compounds with enhanced efficiency.


Polymerization Reactions of Zinc diethyldithiocarbamate: Zinc diethyldithiocarbamate is also instrumental in polymerization reactions, where it acts as a catalyst, promoting the formation of polymers with desirable properties.
Zinc diethyldithiocarbamate is used as accelerator for rubber and latex vulcanization; as heat stabilizer for polyethylene; as stabilizer for butyl rubber, butadiene, and urethane rubbers; as antifouling agent; as fungicide seed disinfectant;


Zinc diethyldithiocarbamate is used activator and accelerator for natural rubber, styrene-butadiene, nitrile-butadiene, and butyl rubber.
Zinc diethyldithiocarbamate can be used as an organocatalyst for the synthesis of high molecular weight polyurethanes from PEG- and PPG-diol macromonomers for use in biomedical applications.


In comparison to other zinc catalysts, Zinc diethyldithiocarbamate demonstrated outstanding activity in the preparation of polyurethanes because of its tolerance to different organic solvents.
Zinc diethyldithiocarbamate can also be used as: A catalyst for the polymerization of olefin oxides.


A precursor to prepare zinc sulfide semiconductor nanowires, which can be used as building blocks for photonic devices.
Zinc diethyldithiocarbamate has been used as an injection solution for the treatment of infectious diseases such as tuberculosis, leprosy, brucellosis, and malaria.


Zinc diethyldithiocarbamate is also used as a pharmacological agent for the treatment of myocardial infarction.
Zinc diethyldithiocarbamate is used as activator; accelerator for natural rubber, styrene-butadiene, nitrile-butadiene, and butyl rubber.
Zinc diethyldithiocarbamate is used as a common accelerator to latex.


-Pharmaceutical Industry uses of Zinc diethyldithiocarbamate:
Zinc diethyldithiocarbamate serves as a catalyst in pharmaceutical synthesis, facilitating the production of vital drugs and pharmaceutical compounds.
Its efficiency and reliability make Zinc diethyldithiocarbamate an indispensable component in drug manufacturing processes.


-Automotive Sector uses of Zinc diethyldithiocarbamate:
Zinc diethyldithiocarbamate is utilized in the automotive industry as a catalyst for various reactions involved in the production of automotive parts and coatings.
Zinc diethyldithiocarbamate contributes to the development of products with enhanced durability and performance characteristics.



COMPOUND TYPE OF ZINC DIETHYLDITHIOCARBAMATE:
*Amine
*Industrial/Workplace Toxin
*Organic Compound
*Organometallic
*Synthetic Compound
*Zinc Compound



ALTERNATIVE PARENTS OF ZINC DIETHYLDITHIOCARBAMATE:
*Organopnictogen compounds
*Organonitrogen compounds
*Organic salts
*Hydrocarbon derivatives
*Substituents
*Organic nitrogen compound
*Organopnictogen compound
*Hydrocarbon derivative
*Organic salt
*Organosulfur compound
*Organonitrogen compound
*Aliphatic acyclic compound



SAFE STORAGE OF ZINC DIETHYLDITHIOCARBAMATE:
Zinc diethyldithiocarbamate should be stored in a cool, dry place, away from incompatible substances and sources of ignition.



COMPOSITION OF ZINC DIETHYLDITHIOCARBAMATE:
Each molecule of Zinc diethyldithiocarbamate contains zinc at its center, tightly bound to two diethyldithiocarbamate ligands.
This composition offers exceptional stability and promotes efficient catalytic activities.



MOLECULAR FORMULA OF ZINC DIETHYLDITHIOCARBAMATE:
The molecular formula, C10H20N2S4Zn, provides clear insights into the specific arrangement of atoms within Zinc diethyldithiocarbamate, facilitating a comprehensive understanding of its chemical properties.



WHAT IS ZINC DIETHYLDITHIOCARBAMATE AND WHERE IS ZINC DIETHYLDITHIOCARBAMATE FOUND?
Zinc diethyldithiocarbamate is used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.
Zinc diethyldithiocarbamate is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of this chemical.



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIETHYLDITHIOCARBAMATE:
Molecular Weight :361.9 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 4
Exact Mass :359.980075 g/mol
Monoisotopic Mass: 359.980075 g/mol
Topological Polar Surface Area :72.7Ų
Heavy Atom Count :17
Formal Charge: 0
Complexity: 73
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
CAS Number: 14324-55-1
Molecular Weight: 361.93
EC Number: 238-270-9
MDL number: MFCD00064798
Physical state: powder
Color: white
Odor: No data available
Melting point/freezing point:
Melting point/range: 178 - 181 °C - lit.
Initial boiling point and boiling range: 301 °C at 1.013 hPa
Flammability (solid, gas): The product is not flammable. - Flammability (solids)
Upper/lower flammability or explosive limits: No data available
Flash point: No data available

Autoignition temperature: does not ignite
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00106 g/l at 20 °C
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,47 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

CAS: 14324-55-1
Molecular Formula: C10H20N2S4Zn
Molecular Weight (g/mol): 361.904
MDL Number: MFCD00064798
InChI Key: RKQOSDAEEGPRER-UHFFFAOYSA-L
PubChem CID: 26633
IUPAC Name: zinc;N,N-diethylcarbamodithioate
SMILES: CCN(CC)C(=S)[S-].CCN(CC)C(=S)[S-].[Zn+2]
Melting Point: 178°C to 183°C
Color: White
Density: 1.48 g/mL
pH: 7.8
Flash Point: 204°C (400°F)
Odor: Odorless
Linear Formula: Zn[CS2N(CH2CH3)2]2

UN Number: UN3077
Solubility Information: Insoluble in water.
Soluble in benzene carbon disulfide and organic liquids.
Formula Weight: 361.9
Concentration or Composition (by Analyte or Components): Zn 17 to 19.5%
Physical Form: Crystalline
Chemical Name or Material: Zinc diethyldithiocarbamate
Formula: C₅H₁₁NS₂
MW: 361,90 g/mol
Melting Pt: 178…183 °C
Density: 1,48
Flash Pt: 204 °C (400 °F)
Storage Temperature: Ambient
MDL Number: MFCD00064798
CAS Number: 14324-55-1
EINECS: 238-270-9

Molecular Formula / Molecular Weight: C10H20N2S4Zn = 361.90
Physical State (20 deg.C): Solid
CAS RN: 14324-55-1
Reaxys Registry Number: 3717403
PubChem Substance ID: 87567161
MDL Number: MFCD00064798
Compound Formula: C10H20N2S4Zn
Molecular Weight: 361.93
Appearance: solid
Melting Point: N/A
Boiling Point: N/A
Density: N/A
Solubility in H2O: N/A
Exact Mass: N/A
Monoisotopic Mass: 361.948212
Charge: N/A

Linear Formula: [(C2H5)2NCS2]2Zn
MDL Number: MFCD00064798
EC No.: 238-270-9
Beilstein/Reaxys No.: N/A
Pubchem CID: N/A
IUPAC Name: N/A
SMILES: [Zn+2].S=C([S-])N(CC)CC.[S-]C(=S)N(CC)CC
InchI Identifier: InChI=1S/2C5H11NS2.Zn/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InchI Key: RKQOSDAEEGPRER-UHFFFAOYSA-L
CBNumber:CB4176909
Molecular Formula:C10H20N2S4Zn
Molecular Weight:361.93
MDL Number:MFCD00064798
MOL File:136-94-7.mol
Melting point: 178-181 °C(lit.)
FDA 21 CFR: 175.105; 177.2600

Chemical Formula: C10H20N2S4Zn
Average Molecular Mass: 361.948 g/mol
Monoisotopic Mass: 359.980 g/mol
CAS Registry Number: 14324-55-1
IUPAC Name: bis[(diethylcarbamothioyl)sulfanyl]zinc
Traditional Name: bis[(diethylcarbamothioyl)sulfanyl]zinc
SMILES CCN(CC)C(=S)S[Zn]SC(=S)N(CC)CC
InChI Identifier: InChI=1S/2C5H11NS2.Zn/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InChI Key: InChIKey=RKQOSDAEEGPRER-UHFFFAOYSA-L
Water Solubility: 0.035 g/L
logP: 3.92
logP: 3.11
logS: -4
Physiological Charge: 0
Hydrogen Acceptor Count: 0

Hydrogen Donor Count: 0
Polar Surface Area: 6.48 Ų
Rotatable Bond Count: 8
Refractivity: 88.24 m³·mol⁻¹
Polarizability: 34.08 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes
Molecular Weight:361.93
Exact Mass:359.980072
EC Number:238-270-9
UNII:ICW4708Z8G

DSSTox ID:DTXSID5021463
Color/Form:White powder
HScode:29302000
PSA:70.66000
XLogP3:2.31750
Appearance:solid
Density:1.47 g/cm3 @ Temp: 20 °C
Melting Point:172-176 °C
Boiling Point:330.6°C (estimate)
Flash Point:204°(400°F)
Water Solubility:Insoluble in water.
soluble in benzene carbon disulfide and organic liquids.
Vapor Pressure:1.1mmHg at 25°C



FIRST AID MEASURES of ZINC DIETHYLDITHIOCARBAMATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIETHYLDITHIOCARBAMATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC DIETHYLDITHIOCARBAMATE:
-Extinguishing media
*Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIETHYLDITHIOCARBAMATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIETHYLDITHIOCARBAMATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC DIETHYLDITHIOCARBAMATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

ZINC DIETHYLDITHIOCARBAMATE
DESCRIPTION:

Zinc diethyldithiocarbamate is a chelating ligand.
Zinc diethyldithiocarbamate is used as a common accelerator to latex.
A fast curing primary or secondary effective ultra-accelerator for natural and synthetic latex compounds.

CAS, 14324-55-1
European Community (EC) Number: 238-270-9
Molecular Formula, C10H20N2S4Zn
Molecular Weight (g/mol), 361.904
IUPAC Name, zinc;N,N-diethylcarbamodithioate


SYNONYMS OF ZINC DIETHYLDITHIOCARBAMATE:
zinc diethyldithiocarbamate, ethyl ziram, zinc bis diethyldithiocarbamate, diethyldithiocarbamic acid zinc salt, zinc n,n-diethylcarbamodithioate, ethyl zimate, unii-icw4708z8g, ditiocarb zinc, zdc, zdec, Bis(diethyldithiocarbamato)zinc; Carbamodithioic acid, diethyl-, zinc salt; Diethyldithiocarbamic acid zinc salt; Ethazate; Ethyl Ziram; Ethyl cymate; Ethyl zimate; Ethylzimate; Hermat ZDK; Nocceler EZ; Soxinol EZ; Vulcacure ZE; Vulkacit LDA; Vulkacit ZDK; Zimate, ethyl; Zinc N,N-diethyldithiocarbamate; Zinc bis(diethyldithiocarbamate); Zinc diethylcarbamodithioate; Zinc diethyldithiocarbamate (VAN); Zinc, bis(diethylcarbamodithioato-S,S')-, (T-4)-; Zinc, bis(diethyldithiocarbamato); Zinc, tetrakis(diethylcarbamodithioato)di-; [ChemIDplus],Ammonium Salt Ditiocarb,Bismuth Salt Ditiocarb,Diethylcarbamodithioic Acid,Diethyldithiocarbamate,Diethyldithiocarbamate, Sodium,Diethyldithiocarbamate, Zinc,Diethyldithiocarbamic Acid,Dithiocarb,Ditiocarb,Ditiocarb Sodium,Ditiocarb, Ammonium Salt,Ditiocarb, Bismuth Salt,Ditiocarb, Lead Salt,Ditiocarb, Potassium Salt,Ditiocarb, Sodium Salt,Ditiocarb, Sodium Salt, Trihydrate,Ditiocarb, Tin(4+) Salt,Ditiocarb, Zinc Salt,Imuthiol,Lead Salt Ditiocarb,Potassium Salt Ditiocarb,Sodium Diethyldithiocarbamate,Sodium Salt Ditiocarb,Sodium, Ditiocarb,Thiocarb,Zinc Diethyldithiocarbamate,Zinc Salt Ditiocarb,Zinc diethyldithiocarbamate,14324-55-1,Ethyl Ziram,Ditiocarb ZINC,Zinc bis(diethyldithiocarbamate),zinc;N,N-diethylcarbamodithioate,136-94-7,Bis(diethyldithiocarbamato)zinc,Zinc N,N-diethyldithiocarbamate,bis(Diethylcarbamothioylthio)zinc,Diethyldithiocarbamic acid zinc salt,ZINCDIETHYLDITHIOCARBAMATE,DTXSID5021463,Ethyl zimate,Ethylzimate,Ethazate,Ethyl cymate,Vulcacure ZE,Nocceler EZ,Soxinol EZ,Vulkacit LDA,Vulkacit ZDK,Hermat ZDK,Zinc diethylcarbamodithioate,ETHYLZIRAM,SCHEMBL48550,Zinc Diethyl Dithio,Carbamate,diethyldithiocarbamate zinc salt,DTXCID901463,ICW4708Z8,CHEMBL3182813,zinc bis(diethylcarbamodithioate),CHEBI:144351,RKQOSDAEEGPRER-UHFFFAOYSA-L,Tox21_200263,AKOS030228292,zinc bis(diethylthiocarbamoyl)disulfide,DIETHYLCARBAMIC ACID, ZINC SALT,NSC-177699,zinc bis(diethyldithiocarbamoyl)disulfide,NCGC00257817-01,zinc bis(diethyldithiocarbamoyl)disulphide,CAS-14324-55-1,D0492,FT-0624885,NS00087819,E75979,DIETHYLDITHIOCARBAMIC ACID ZINC SALT [HSDB],J-007778,(T-4)-bis(diethylcarbamodithioato-kappaS,kappaS')zinc,Q16295596



Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.

Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).
Zinc diethyldithiocarbamate is functionally related to a diethyldithiocarbamic acid.


Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc.
Zinc diethyldithiocarbamate also a dermatological sensitizer and allergen.
Sensitivity to ditiocarb zinc may be identified with a clinical patch test.

Zinc diethyldithiocarbamate is a Standardized Chemical Allergen.
The physiologic effect of zinc diethyldithiocarbamate is by means of Increased Histamine Release, and Cell-mediated Immunity.
The chemical classification of zinc diethyldithiocarbamate is Allergens.


Zinc diethyldithiocarbamate (ZDDC), an organo-metallic compound, has found extensive use in scientific and industrial applications over the years.
Zinc diethyldithiocarbamate presents itself as a white powder, soluble in both water and organic solvents, and exhibits strong metal-chelating properties.
ZDDC serves as a catalyst and reagent in various laboratory reactions and processes.


Within the realm of scientific research, Zinc diethyldithiocarbamate has been harnessed across diverse applications.
Zinc diethyldithiocarbamate has facilitated the study of metal-catalyzed reactions, enabling the synthesis of novel compounds and offering insights into their properties.
Additionally, ZDDC has been instrumental in exploring biochemical and physiological processes, including the effects of metals on enzyme and protein activity.

The interaction of Zinc diethyldithiocarbamate with metals leads to the formation of chelate complexes.
These complexes subsequently bind to proteins and enzymes, resulting in the inhibition of their activity.
The metal chelation by ZDDC also exerts additional effects, such as the inhibition of specific biochemical reactions and the modulation of certain enzyme activities.




APPLICATIONS OF ZINC DIETHYLDITHIOCARBAMATE:
Zinc diethyldithiocarbamate (Zn(S2CNEt2)2, ZDTC) can be used as an organocatalyst for the synthesis of high molecular weight polyurethanes from PEG- and PPG-diol macromonomers for use in biomedical applications.
In comparison to other zinc catalysts, ZDTC demonstrated outstanding activity in the preparation of polyurethanes because of its tolerance to different organic solvents.

It can also be used as:

A catalyst for the polymerization of olefin oxides.
A precursor to prepare zinc sulfide semiconductor nanowires, which can be used as building blocks for photonic devices.


Zinc diethyldithiocarbamate is used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.
Zinc diethyldithiocarbamate is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of this chemical.


Zinc diethyldithiocarbamate is found in rubber.
Zinc diethyldithiocarbamate is used to accelerate the production of rubber.

Zinc diethyldithiocarbamate (Zn(S2CNEt2)2, ZDTC) can be used as an organocatalyst for the synthesis of high molecular weight polyurethanes from PEG- and PPG-diol macromonomers for use in biomedical applications.

In comparison to other zinc catalysts, Zinc diethyldithiocarbamate demonstrated outstanding activity in the preparation of polyurethanes because of its tolerance to different organic solvents.
Zinc diethyldithiocarbamate can also be used as: A catalyst for the polymerization of olefin oxides.
A precursor to prepare zinc sulfide semiconductor nanowires, which can be used as building blocks for photonic devices.

Zinc diethyldithiocarbamate is an inorganic compound that has been shown to have potent anti-inflammatory and antipyretic properties.
Zinc diethyldithiocarbamate has been used as a chemical inhibitor of phospholipase A2, which is an enzyme involved in the inflammatory process.
Zinc diethyldithiocarbamate also has been shown to be a potent inducer of metallothionein and other proteins that are involved in detoxification processes.

Zinc diethyldithiocarbamate has been used as an injection solution for the treatment of infectious diseases such as tuberculosis, leprosy, brucellosis, and malaria.
Zinc diethyldithiocarbamate is also used as a pharmacological agent for the treatment of myocardial infarction.




CHEMICAL AND PHYSICAL PROPERTIES OF ZINC DIETHYLDITHIOCARBAMATE:
Melting Point, 178°C to 183°C
Color, White
Density, 1.48 g/mL
pH, 7.8
Flash Point, 204°C (400°F)
Odor, Odorless
Linear Formula, Zn[CS2N(CH2CH3)2]2
Quantity, 2 kg
UN Number, UN3077
Solubility Information, Insoluble in water. Soluble in benzene carbon disulfide and organic liquids.
CAS, 14324-55-1
European Community (EC) Number: 238-270-9
Molecular Formula, C10H20N2S4Zn
Molecular Weight (g/mol), 361.904
IUPAC Name, zinc;N,N-diethylcarbamodithioate
Molecular Weight
361.9 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
359.980075 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
359.980075 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
72.7Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
17
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
73
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
3
Computed by PubChem
Compound Is Canonicalized
Yes
Quality Level
100
Assay
97%
reaction suitability
core: zinc
reagent type: catalyst

mp
178-181 °C (lit.)
SMILES string
CCN(CC)C(=S)S[Zn]SC(=S)N(CC)CC
InChI
1S/2C5H11NS2.Zn/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InChI key
RKQOSDAEEGPRER-UHFFFAOYSA-L
Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
178-181° C (lit.)
Boiling Point :
301° C
Product Number, D0492
Purity / Analysis Method, >99.0%(T)
Molecular Formula / Molecular Weight, C10H20N2S4Zn = 361.90
Physical State (20 deg.C), Solid
CAS RN, 14324-55-1
Reaxys Registry Number, 3717403
PubChem Substance ID, 87567161
MDL Number, MFCD00064798
Appearance, White to Almost white powder to crystal
Purity(Chelometric Titration), min. 99.0 %
Melting point, 178.0 to 182.0 °C
Properties (reference)
Melting Point, 181 °C
Solubility in water, Insoluble
Solubility (soluble in), Chloroform, Benzene
Solubility (slightly sol. in), Acetone
Chemical Name or Material, Zinc Diethyldithiocarbamate
Melting Point, 181°C
Molecular Formula, C10H20N2S4Zn
Quantity, 500 g
Synonym, zinc diethyldithiocarbamate, ethyl ziram, zinc bis diethyldithiocarbamate, diethyldithiocarbamic acid zinc salt, zinc n,n-diethylcarbamodithioate, ethyl zimate, unii-icw4708z8g, ditiocarb zinc, zdc, zdec
SMILES, CCN(CC)C(=S)[S-].CCN(CC)C(=S)[S-].[Zn+2]
Molecular Weight (g/mol), 361.904
Formula Weight, 361.90
Physical Form, Crystalline Powder
CAS, 14324-55-1
Color, White-Yellow
MDL Number, MFCD00064798
UN Number, 3077
InChI Key, RKQOSDAEEGPRER-UHFFFAOYSA-L
IUPAC Name, zinc;N,N-diethylcarbamodithioate
PubChem CID, 26633
Percent Purity, ≥99.0% (T)



SAFETY INFORMATION ABOUT ZINC DIETHYLDITHIOCARBAMATE:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


ZINC DIETHYLDITHIOCARBAMATE (ZDEC)

Zinc diethyldithiocarbamate (ZDEC) is a chemical compound that falls into the category of dithiocarbamates. Its chemical formula is C10H20N2S4Zn.
Zinc diethyldithiocarbamate (ZDEC) is commonly used as an accelerator in the rubber industry, particularly in the production of latex goods and rubber products.
Accelerators are substances that hasten the vulcanization of rubber, which is the process of converting natural or synthetic rubber into a more durable and elastic material.

CAS Number: 14324-55-1
EC Number: 238-270-9



APPLICATIONS


Zinc diethyldithiocarbamate (ZDEC) is widely used as an accelerator in the rubber industry for the vulcanization of natural and synthetic rubbers.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role in the production of tires, providing enhanced strength and durability.

Zinc diethyldithiocarbamate (ZDEC) is commonly employed in the manufacturing of conveyor belts, ensuring they maintain resilience under various conditions.
Latex goods, including gloves and medical products, benefit from ZDEC's contribution to rubber vulcanization.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the production of automotive rubber parts, such as seals and gaskets.

Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber hoses, ensuring they withstand pressure and environmental factors.
Zinc diethyldithiocarbamate (ZDEC) is an essential component in the production of shoe soles, improving the wear resistance of rubber footwear.
Zinc diethyldithiocarbamate (ZDEC) is used in the fabrication of industrial rubber sheets with enhanced mechanical properties.

Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized fabrics, providing them with increased strength and flexibility.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of anti-vibration rubber products, such as mounts and dampers.
Sporting goods like tennis balls and athletic shoe soles benefit from ZDEC in their manufacturing processes.

Rubber linings for chemical and industrial equipment utilize ZDEC to enhance resistance to abrasion and chemicals.
Zinc diethyldithiocarbamate (ZDEC) is integral in the production of cable insulation and other electrical rubber components.
Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized coatings for corrosion protection in various applications.

Zinc diethyldithiocarbamate (ZDEC) finds use in the production of agricultural rubber products, including hoses and belts for machinery.
Zinc diethyldithiocarbamate (ZDEC) is used in the manufacturing of seals and gaskets for appliances, ensuring longevity and reliability.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized roofing materials for weatherproofing and durability.

Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubber compounds for footwear, providing comfort and durability.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the production of rubberized rollers and belts used in industrial machinery.

Zinc diethyldithiocarbamate (ZDEC) is an important ingredient in the formulation of rubber adhesives and sealants.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the creation of marine rubber products, such as boat fenders and seals.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of molded rubber components used in automotive and industrial applications.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the formulation of rubber compounds for automotive belts, ensuring efficient power transmission.

Zinc diethyldithiocarbamate (ZDEC) is employed in the production of rubberized flooring materials for commercial and industrial spaces.
Zinc diethyldithiocarbamate (ZDEC)'s applications extend to various industries, reflecting its versatility and significance in rubber processing.

Zinc diethyldithiocarbamate (ZDEC) is commonly used in the formulation of rubber seals and gaskets for aerospace applications, ensuring reliability and performance under extreme conditions.
Zinc diethyldithiocarbamate (ZDEC) is employed in the production of automotive rubber bushings, contributing to the suspension system's durability and resilience.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the creation of rubberized components for household appliances, such as washing machine seals and hoses.

Zinc diethyldithiocarbamate (ZDEC) is utilized in the manufacturing of inflatable structures, such as rubberized tents and bladders.
Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for anti-fatigue mats, enhancing their longevity and comfort.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized conveyor belts used in mining and material handling industries.
Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubberized footwear for industrial and safety applications, providing protection and comfort.

Zinc diethyldithiocarbamate (ZDEC) is integral in the production of rubberized wheels and casters for material handling equipment.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized rollers for printing and industrial processing machinery.
Zinc diethyldithiocarbamate (ZDEC) finds use in the manufacturing of rubberized inflatable boats, providing durability in marine environments.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized automotive components, including engine mounts and suspension parts.

Zinc diethyldithiocarbamate (ZDEC) is utilized in the formulation of rubber compounds for railway applications, such as track pads and seals.
Zinc diethyldithiocarbamate (ZDEC) is employed in the production of rubberized gloves used in chemical and industrial settings.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the formulation of rubberized diaphragms for pumps and valves in various industries.

Zinc diethyldithiocarbamate (ZDEC) is used in the creation of rubberized packing materials for sealing joints and connections.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized wheels for carts and trolleys in industrial and commercial settings.

Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for oil and gas industry components, such as seals and gaskets.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized components for medical devices, ensuring biocompatibility and durability.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the manufacturing of rubberized expansion joints for bridges and infrastructure projects.

Zinc diethyldithiocarbamate (ZDEC) plays a role in the production of rubberized roller skate wheels, providing resilience and grip.
Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubberized agricultural belts for machinery such as combines and tractors.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized inflatable seals used in aerospace and industrial applications.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized components for water treatment and wastewater systems.

Zinc diethyldithiocarbamate (ZDEC) finds use in the formulation of rubberized components for the production of footwear in the fashion industry.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the manufacturing of rubberized anti-vibration mounts for machinery and equipment.

Zinc diethyldithiocarbamate (ZDEC) is commonly employed in the formulation of rubberized automotive weatherstripping, contributing to the sealing of vehicle doors and windows.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role in the production of rubberized rollers used in the printing and paper industry for material transport.
Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for the production of inflatable airbags in automotive safety systems.

Zinc diethyldithiocarbamate (ZDEC) is used in the creation of rubberized conveyor belts for food processing and packaging applications.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized components for escalator and elevator systems, ensuring smooth and reliable operation.
Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized pipe seals, providing resistance to environmental factors and maintaining tight seals.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the manufacturing of rubberized diaphragms for control valves and actuators in industrial processes.

Zinc diethyldithiocarbamate (ZDEC) is utilized in the production of rubberized vibration isolation mounts for electronic equipment and sensitive machinery.
Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubber compounds for the production of seals and gaskets in plumbing applications.
Zinc diethyldithiocarbamate (ZDEC) finds application in the creation of rubberized components for amusement park rides, ensuring safety and durability.

Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized conveyor belts used in the mining and aggregates industry.
Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized components for marine fender systems, providing impact resistance at docks and ports.
Zinc diethyldithiocarbamate (ZDEC) is used in the manufacturing of rubberized expansion joints for bridges and highway construction projects.

Zinc diethyldithiocarbamate (ZDEC) plays a role in the formulation of rubber compounds for the production of durable and weather-resistant roofing materials.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the creation of rubberized components for fitness equipment, such as treadmill belts and resistance bands.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized components for air handling systems, including HVAC duct connectors.

Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized components for water and wastewater treatment plants, providing chemical resistance.
Zinc diethyldithiocarbamate (ZDEC) finds application in the creation of rubberized components for military and defense applications, such as protective gear and equipment.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role in the production of rubberized components for oil rigs and offshore platforms, withstanding harsh environmental conditions.

Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubberized components for medical devices, ensuring compliance with healthcare standards.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized components for the aerospace industry, including seals and gaskets for aircraft.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized components for solar panel installations, providing durability and weather resistance.

Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for the production of durable and slip-resistant sports surfaces.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the manufacturing of rubberized components for the construction industry, including seals for doors and windows.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the creation of rubberized components for renewable energy applications, such as wind turbine seals and gaskets.



DESCRIPTION


Zinc diethyldithiocarbamate (ZDEC) is a chemical compound that falls into the category of dithiocarbamates. Its chemical formula is C10H20N2S4Zn.
Zinc diethyldithiocarbamate (ZDEC) is commonly used as an accelerator in the rubber industry, particularly in the production of latex goods and rubber products.
Accelerators are substances that hasten the vulcanization of rubber, which is the process of converting natural or synthetic rubber into a more durable and elastic material.

Zinc diethyldithiocarbamate (ZDEC), like other dithiocarbamates, contains a dithiocarbamate group (-S2CNRR'), where R and R' are organic groups.
The presence of zinc in ZDEC provides additional stability and effectiveness as a vulcanization accelerator.

Zinc diethyldithiocarbamate, commonly known as ZDEC, is a chemical compound used in the rubber industry.
Zinc diethyldithiocarbamate (ZDEC) is characterized by its molecular formula C10H20N2S4Zn.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role as a vulcanization accelerator in the production of rubber products.

With a CAS Registry Number of 14324-55-1, ZDEC is identifiable in chemical databases.
Zinc diethyldithiocarbamate (ZDEC) contains a dithiocarbamate group, which contributes to its rubber vulcanization properties.
The presence of zinc in Zinc diethyldithiocarbamate (ZDEC) enhances its stability and accelerates the vulcanization process.

Rubber goods such as latex products often incorporate ZDEC to improve their durability and elasticity.
As an accelerator, Zinc diethyldithiocarbamate (ZDEC) facilitates the cross-linking of polymer chains in rubber, enhancing its strength.
Zinc diethyldithiocarbamate (ZDEC) is integral in ensuring that rubber products achieve the desired physical properties.
Zinc diethyldithiocarbamate (ZDEC) is used in the production of various rubber items, including tires, hoses, and conveyor belts.

Its EC number, 238-270-9, is associated with its registration in the European Community.
Zinc diethyldithiocarbamate (ZDEC) has a white to pale yellow appearance in its physical state.
Zinc diethyldithiocarbamate (ZDEC) is soluble in common organic solvents, contributing to its ease of use in rubber processing.
Safety data sheets should be consulted and safety precautions followed when handling ZDEC.

Zinc diethyldithiocarbamate (ZDEC) undergoes chemical reactions that promote the curing and hardening of rubber.
Zinc diethyldithiocarbamate (ZDEC)'s application is particularly prevalent in the synthesis of vulcanized rubber for industrial purposes.
Manufacturers carefully control the concentration of ZDEC to achieve optimal vulcanization results.
The molecular structure of ZDEC reflects its ability to act as an efficient accelerator in rubber chemistry.

Rubber compounds with ZDEC exhibit improved resistance to heat, wear, and aging.
Zinc diethyldithiocarbamate (ZDEC) is a key component in formulating rubber compounds with specific performance characteristics.

Zinc diethyldithiocarbamate (ZDEC)'s effectiveness in promoting vulcanization makes it a valuable tool in rubber engineering.
Zinc diethyldithiocarbamate (ZDEC) is part of a family of chemicals known for their contributions to rubber curing processes.
Rubber chemists and engineers rely on ZDEC to achieve precise control over the vulcanization kinetics.

Zinc diethyldithiocarbamate (ZDEC)'s role in rubber processing aligns with the industry's quest for enhanced product performance.
The utilization of Zinc diethyldithiocarbamate (ZDEC) as a vulcanization accelerator underscores its importance in modern rubber technology.



PROPERTIES


Chemical Formula: C10H20N2S4Zn
CAS Registry Number: 14324-55-1
EC Number: 238-270-9
Molecular Weight: Approximately 361.94 g/mol
Physical State: Solid
Color: White to pale yellow
Solubility: Soluble in common organic solvents
Melting Point: Varies, typically in the range of 136-142°C (277-288°F)
Density: Varies, depending on the form and concentration
Odor: May have a characteristic odor
Stability: Stable under normal conditions
Compatibility: Compatible with various rubber polymers
Role: Rubber vulcanization accelerator
Vulcanization Enhancement: Promotes cross-linking of polymer chains in rubber
Accelerator Type: Dithiocarbamate
Presence of Zinc: Enhances stability and accelerates vulcanization
Industrial Applications: Widely used in the rubber industry
Applications: Tire manufacturing, conveyor belts, latex goods, automotive rubber parts, hoses, shoe soles, sporting goods, industrial rubber sheets, seals, gaskets, and various rubber products.
Biodegradability: Information on biodegradability may vary; proper disposal methods recommended.



FIRST AID


Inhalation:

Move the affected person to fresh air.
If the person is not breathing, administer artificial respiration.
Seek medical attention promptly.


Skin Contact:

Remove contaminated clothing.
Wash the affected area with plenty of soap and water.
Seek medical attention if irritation persists or if there are signs of chemical burns.


Eye Contact:

Rinse eyes with plenty of water for at least 15 minutes, lifting the eyelids occasionally.
Seek medical attention if irritation persists or if there is any visual impairment.


Ingestion:

Do not induce vomiting unless directed by medical personnel.
Rinse the mouth with water if the person is conscious.
Seek immediate medical attention.



HANDLING AND STORAGE


Handling Conditions:

Personal Protective Equipment (PPE):
When handling ZDEC, wear appropriate personal protective equipment, including gloves, safety glasses, and a lab coat or protective clothing, to minimize skin contact and protect the eyes.

Ventilation:
Use the chemical in a well-ventilated area to prevent the buildup of vapors.
If ventilation is insufficient, consider using respiratory protection.

Avoid Contact:
Avoid direct skin contact with ZDEC.
In case of skin contact, wash affected areas thoroughly with soap and water.
If irritation persists, seek medical attention.

Avoid Inhalation:
Inhalation of dust or vapors should be avoided.
If respiratory protection is necessary, use appropriate equipment based on workplace exposure levels.

Handling Procedures:
Follow good laboratory or industrial hygiene practices.
Wash hands thoroughly after handling ZDEC and before eating, drinking, or smoking.

Spill Response:
In case of spills, contain the material and clean it up promptly. Use appropriate absorbent materials, and follow established spill response procedures. Dispose of waste in accordance with local regulations.

Storage Compatibility:
Store ZDEC away from incompatible materials, such as strong acids and bases.
Ensure that storage containers are made of materials resistant to corrosion and deterioration.

Temperature Control:
Store ZDEC in a cool, dry place away from direct sunlight and heat sources.
Maintain appropriate temperature conditions to prevent degradation.


Storage Conditions:

Container Selection:
Use containers made of materials compatible with ZDEC.
Consider using tightly sealed containers to prevent moisture ingress.

Labeling:
Clearly label containers with the chemical name, hazard information, and appropriate safety symbols.
This aids in proper identification and safe handling.

Segregation:
Store ZDEC away from incompatible substances to prevent cross-contamination.
Follow segregation guidelines based on chemical compatibility.

Fire Prevention:
ZDEC is not typically considered highly flammable, but it's essential to store it away from open flames, sparks, and heat sources.

Security:
Limit access to storage areas to authorized personnel only.
Store ZDEC in areas designated for chemical storage and ensure compliance with relevant security measures.

Shelf Life:
Adhere to the recommended shelf life of ZDEC as specified by the supplier.
Rotate stock as needed to use older material first.

Monitoring:
Periodically inspect storage areas for signs of damage, leaks, or deterioration of containers.
Address any issues promptly to maintain a safe storage environment.

Emergency Equipment:
Keep emergency response equipment, such as spill kits and fire extinguishers, readily available in the vicinity of the storage area.



SYNONYMS


ZDEC
EZ
Zink-diethyl-dithiocarbamat (German)
Diethyldithiocarbamic Acid Zinc Salt
Ethyl Zimate
Perkacit ZDEC
Rhenocure ZDEC
Rubber Accelerator ZDEC
Zinc Diethyldithiocarbamate
Zinc Diethylthiocarbamate
Zinc Salt of Diethyldithiocarbamic Acid
Zinc Bis(diethylcarbamodithioate)
Zinc Diethylxanthate
Diethylzinc Dithiocarbamate
Zinc(II) N,N-Diethyldithiocarbamate
ZDEC Accelerator
Zinc Salt of Diethyldithiocarbamate
N,N-Diethyldithiocarbamic Acid Zinc Salt
Bis(diethyldithiocarbamato)zinc
Zinc(II) Diethyldithiocarbamate
Zinc(II) Ethylxanthate
Perkacit EZ
Accicure ZDEC
Ethyl Ziram
Zinc Ethylxanthate
Zinc Diethyl Dithiocarbamate
Ethyl N,N-Diethyldithiocarbamate Zinc Salt
Rhenogran ZDEC-80
Rubber Accelerator PX
Zinc(II) Salt of Diethyldithiocarbamic Acid
Zink-diethyl-ditiokarbamat (Swedish)
Dithiocarbamic Acid, Zinc Salt, Diethyl Ester
Zineb Accelerator
Zinc(II) Diethyldithiocarbamate
Nocceler ZDEC
Vulkacit L 80
ZINC DI-OCTYL DITHIOPHOSPHATE
ZINC GLUCOHEPTONATE N° CAS : 12565-63-8 Nom INCI : ZINC GLUCOHEPTONATE Nom chimique : Zinc, bis [(2.xi.)-D-gluco-heptonato]- Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état
ZINC GLUCOHEPTONATE
ZINC GLYCINATE N° CAS : 14281-83-5 Nom INCI : ZINC GLYCINATE Nom chimique : Glycine, Zinc Salt N° EINECS/ELINCS : 238-173-1 Classification : Règlementé Restriction en Europe : III/24 Ses fonctions (INCI) Régulateur de pH : Stabilise le pH des cosmétiques
ZINC GLUCONATE
ZINC GLUCONATE = ZINCUM GLUCONICUM = GLUCONIC ACID ZINC SALT


CAS Number: 4468-02-4
EC Number: 224-736-9
Chemical formula: C12H22O14Zn


Zinc Gluconate is obtained by connecting 2 gluconic acids to a Zn +2 zinc cation structurally.
Zinc Gluconate has great importance in biological structure.
Zinc Gluconate is not known exactly what mechanism of action it has.
But Zinc Gluconate is known as an organic zinc supplement agent.


Zinc gluconate is an essential trace element for the proper functioning of many chemical reactions that occur in the human body, as it contributes to the regulation of about 300 enzymes as well as protein synthesis.
Zinc gluconate is the zinc salt of gluconic acid.
Zinc Gluconate is an ionic compound consisting of two anions of gluconate for each zinc(II) cation.


Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement providing 14.35% elemental zinc by weight.
Zinc is an essential mineral responsible for a number of different functions in the human body.
Zinc Gluconate supports healthy immune system functions and cell regeneration.
Zinc Gluconate helps to stimulate the activity of over one hundred different enzymes and it is vital for protein synthesis.


Essential trace element for the body, as Zinc Gluconate is a key ingredient for more than 150 enzymes.
Zinc Gluconate plays a key role in the process of protein synthesis (DNA & RNA synthesis) and due to this property it shows a wide range of indications.
Zinc Gluconate is a nutritional supplement containing the zinc salt form of gluconic acid for the purpose of providing zinc.


As an essential trace element, zinc is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system.
Zinc Gluconate is available in the form of white powder or granules.
The pH value of Zinc Gluconate is in the range of 5.5-7.5 in its solution at 0.01 g/ml.
Zinc Gluconate dissolves well in water as solubility.


Zinc Gluconate is insoluble in methylene chloride and pure ethanol .
Zinc Gluconate's melting point is in the range of 172-175 °C.
Zinc Gluconate's Boiling Point is 673.6 °C.


Zinc Gluconate's density is 2.907 g/cm3 .
Zinc Gluconate store away from moisture and at room temperature.
There are different forms of zinc, with zinc gluconate being the most common.
Studies show that in the elderly population, zinc supplements potentially improve immunity.


Zinc is a mineral in nature.
In the body, this is called an "essential trace element" because a very small amount of zinc already has an essential role for human health.
Since the human body cannot store excess zinc, this element needs to be consumed regularly as part of the daily diet.
Common natural food sources of zinc include red meat, poultry, and fish.


Zinc deficiency can result in short stature in young children, reduced ability to taste and smell, and limited activity in the testicles and ovaries.
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+).
Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA.


Zinc Gluconate is a L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo.
Zinc gluconate (also called zincum gluconicum) is the zinc salt of gluconic acid.
Zinc Gluconate is an ionic compound consisting of two moles of gluconate for each mole of zinc.
Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement.


Gluconic acid is found naturally, and is industrially manufactured by the fermentation of glucose, but also by other fungi, e.g. Penicillium, or by bacteria, e.g. Acetobacter, Pseudomonas and Gluconobacter. In its pure form, it is a white to off-White powder.
Zinc Gluconate can also be manufactured by electrolytic oxidation, although this is a more expensive process.
The advantages are a lower microbiological profile, and a more complete reaction, yielding a product with a longer shelf life.


Zinc Gluconate is a supplement that can provide zinc to the body.
Zinc Gluconate is zinc salt of gluconic acid, a mild acid produced from the sugar glucose.
Despite the in-part sugar origins, this is a synthetic ingredient that functions as a preservative.
Interestingly, the human body produces gluconates on its own to assist in obtaining nutrients from minerals.


Zinc is an essential mineral responsible for a number of different functions in the human body.
Zinc Gluconate supports healthy immune system functions and cell regeneration.
Zinc Gluconate helps to stimulate the activity of over one hundred different enzymes and it is vital for protein synthesis.
Zinc Gluconate is a nutritional supplement containing the zinc salt form of gluconic acid for the purpose of providing zinc.


Zinc gluconate is produced by complete neutralisation of gluconic acid with a high purity zinc source and subsequent spray-drying.
Zinc gluconate is supplied as a white to almost white, granular or crystalline powder.
Zinc Gluconate shows a good solubility and fast dissolution speed in water and is practically insoluble in alcohol.
Zinc deficiency affects about 1 in 3 people worldwide.


Signs of Zinc deficiency include wounds that take time to heal, trouble concentrating, stomach problems, decreased sense of smell and taste, hair loss, loss of appetite and unexplained weight loss.
Fertility problems can be exacerbated by a lack of sufficient Zinc.
Recurring health problems related to a low immune system could also be an indication of Zinc deficiency.



USES and APPLICATIONS of ZINC GLUCONATE:
Zinc gluconate is considered safe as used in cosmetics.
Zinc Gluconate’s also used in over-the-counter oral lozenges designed to combat the common cold.
Zinc Gluconate is used as a dietary supplement, adults take one tablet daily preferably with a meal or as recommended by a physician.
As a dietary supplement, adults take one (1) tablet daily with a meal or as directed by a health care professional.


Zinc Gluconate is ideal in cases of oligospermia, acne, macular degeneration, ulcers, burns and common cold.
Zinc Gluconate is treated as a dietary supplement to provide the form of gluconic acid.
In medicine, zinc is taken orally to treat and prevent zinc deficiency and its consequences, including growth retardation, acute diarrhea in children, prolonged wound healing, and Wilson's disease.


Besides, elemental zinc, in the form of zinc gluconate salt is also used to strengthen the immune system, improve growth and health in zinc-deficient infants and children, to treat common colds common and recurrent ear infections, influenza, upper respiratory tract infections, prevention and treatment of lower respiratory tract infections as well as used for malaria and other diseases caused by parasites.
Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV).


Zinc Gluconate is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
As a pharmaceutical chemical, gluconic acid plays a role in activating many important enzymes with antioxidant effects.
In this way, Zinc Gluconate has the effect of preventing the damage of oxygen free radicals.


Since Zinc Gluconate is a very good source of zinc, in addition to the effect of inducing T lymphocyte activation, gluconic acid supplemented drugs are produced to protect the metabolic structure by activating B lymphocytes and to ensure the permeability of the cell membrane.
Zinc gluconate (Zinc Gluconate) formulated products are applied in the manufacture of oral care products to reduce bad odors, prevent tartar formation and protect dental plaques.


Zinc Gluconate is used as a food additive in some diet products.
Zinc Gluconate is used as an alternative to zinc sulfate because it has less side effects and better absorption than zinc sulfate.
Biologically, there is approximately 1.6 times more utilization than Zinc sulfate .
Zinc Gluconate is used as a drug active ingredient for the diabetes treatment of people who are not dependent on insulin resistance.


Zinc Gluconate increases the body's insulin sensitivity.
A pressure ulcer results in skin and tissue damage due to reduced blood circulation in a particular area of ​​the body.
Zinc Gluconate is used in the manufacture of drugs or food supplements used in the treatment of pressure ulcers.
The reason for using here is; Zinc has an important role in many enzymatic reactions.


Zinc Gluconate helps to create a mental clarity effect by using it together with Ascorbic Acid , Magnesium Sulphate and Caffeine in the production of Multivitamin Supplements .
Zinc Gluconate is used in the production of drugs containing D-Gluconate for the good functioning of protein synthesis in the body, healing of wounds and stabilization of blood values.


Zinc is a mineral that is used as a dietary supplement in people who do not get enough zinc from food.
Zinc gluconate lozenges are used to help make cold symptoms less severe or shorter in duration.
This includes sore throat, cough, sneezing, stuffy nose, and a hoarse voice.
Zinc gluconate is not effective in treating flu or allergy symptoms.


Zinc gluconate may also be used for purposes not listed in this medication guide.
Zinc is a mineral that is used as a dietary supplement in people who do not get enough zinc from food.
Zinc Gluconate is used as an essential trace element, zinc is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system.


Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV).
Zinc in the form of Zinc Gluconate contains 10mg of elemental Zinc which is easily assimilated in the body.
Zinc is involved in a great number of biological functions.


Zinc Gluconate aids normal cell division, which makes it especially important for growth and development during pregnancy and childhood.
Zinc Gluconate is involved in bone formation and mineralisation, helping to maintain strong bones and teeth.
Zinc also plays an important role in collagen and protein synthesis, vision, sexual function, fertility, antioxidant activity, immunity and much more.


Zinc gluconate is mainly used as a mineral source in functional food, beverages and food supplement preparations.
Zinc Gluconate's excellent solubility properties make it perfect for liquid and powdered applications.
As an organic mineral source, Zinc Gluconate is preferred in many applications over inorganic sources because of its superior bioavailability, physiological compatibility and nearly neutral taste compared to other zinc salts.


Due to its skin-conditioning properties, Zinc Gluconate is also used in skin care products.
Zinc Gluconate can be used as a dietary ingredient and as a nutrient.
Zinc is an important antioxidant nutrient.
Zinc Gluconate is necessary for protein synthesis, wound healing, for blood stability, normal tissue function, and aids in the digestion and metabolism of phosphorus.


Zinc Gluconate also governs the contractility of muscles and maintains the body’s alkaline balance.
Zinc Gluconate helps strengthen the immune system, skin health, healthy sperm production, prostate health and has a high antioxidant effect.
Zinc Gluconate is ideal for protection against colds and viruses.
Zinc Gluconate is used supply of zinc for human and veterinary medicine (oral or injection)


Zinc Gluconate is used in anti-acne preparations and to reduce the duration of common cold symptoms.
Zinc Gluconate is used as a mineral source in dietary supplements, in dairy product, in beverages and in baby food.
Zinc Gluconate is used sequestrant, acidifier, leavening agent, curing agent in nonalcoholic beverages, processed.
Zinc Gluconate is used fruit and fruit juices, baked goods, dairy products and cured meats.


Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children.
Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks.


Zinc is known to play a critical role in cell growth, wound healing, immunity, protein synthesis, DNA synthesis, and it is required for taste and smell to work correctly.
Thus, it is crucial to almost every aspect of your health.
Therefore, people at risk of zinc deficiency are advised to include foods high in zinc in their daily diets.


In certain situations, a doctor might also recommend a zinc supplement.
Zinc gluconate is used as one of the most common OTC forms, zinc gluconate is often used in cold remedies like lozenges and nasal sprays.
Zinc Gluconate’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.


Some patients are also prescribed zinc supplements for an eye disease called macular degeneration, night blindness and cataracts.
On the other hand, the role of zinc has also been demonstrated in asthma, diabetes and diabetes-related nerve damage; High Blood Pressure; HIV/AIDS or pregnancy complications, HIV-associated diarrhea and AIDS-related malabsorption syndromes, AIDS-related infections, and hyperbilirubinemia.


In addition, zinc gluconate is also involved in the treatment of anorexia nervosa, obsessive-compulsive disorder, depression, memory loss, dry mouth, attention deficit hyperactivity disorder, hepatic encephalopathy, liver related diseases to alcohol, ulcerative colitis, inflammatory bowel disease, mouth ulcers, stomach ulcers, leg ulcers, and pressure ulcers.
Main uses Zinc gluconate is an effective treatment for zinc deficiency.


Zinc deficiency can occur in people with severe diarrhea, a condition that makes it difficult for the intestines to absorb food, cirrhosis of the liver, and alcoholism.
This condition can also occur after major surgery and during prolonged use of tube feeding in the hospital.
Indications to use zinc orally or give zinc intravenously will help quickly restore zinc levels in people with zinc deficiency.
However, regular zinc supplementation is not recommended.


-Additional Uses Diarrhea :
Taking zinc gluconate tablets by mouth has been shown to reduce the duration and severity of diarrhea in undernourished or zinc-deficient children.
Severe zinc deficiency in children is a common condition in developing countries.
Simultaneously, clinicians need to provide zinc to undernourished women during pregnancy and continue until one month postpartum to reduce the incidence of neonatal diarrhea within the first year of life.


-Wilson's disease:
Taking zinc daily improves symptoms of a genetic disorder known as Wilson's disease.
People with Wilson's disease often have too much copper in their bodies.
At this time, the element zinc will prevent copper from being absorbed and increase the amount of copper released by the body.


-Skin acne:
Studies show that people with acne have lower blood and skin zinc levels than the general population.
Thus, taking zinc supplements will help treat acne.
However, it is still unclear how beneficial zinc is compared to acne medications such as tetracycline or minocycline.
Therefore, topical application of zinc in ointments does not appear to help treat acne unless used in combination with the antibiotic erythromycin.


-Age-related vision loss:
It is macular degeneration in the elderly.
Observational studies show that people who consume more zinc as part of their diet have a reduced risk of age-related vision loss.
Therefore, supplementation with zinc and antioxidant vitamins may mitigate and prevent age-related vision loss in high-risk individuals.


-Anorexia:
Taking zinc supplements by mouth may help with weight gain and improve symptoms of depression in adolescents and adults with anorexia.
Zinc Gluconate is an over-the-counter dietary supplement that contains a zinc, a mineral that is used throughout the body.
Zinc Gluconate is used to treat zinc-deficiency and as a cold remedy.


-Zinc gluconate and the common cold:
Zinc gluconate has been used in lozenges for treating the common cold.
However, controlled trials with lozenges which include zinc acetate have found it has the greatest effect on the duration of colds.


-Veterinary uses of Zinc Gluconate:
A zinc gluconate-based product, also containing arginine, is used as a veterinary chemical castration drug.
Zinc gluconate, a skin-absorbable zinc derivative, is a powerful sebum stabilizer that visibly rebalances and mattifies the skin.
Zinc Gluconate is an indispensable ingredient for combination and oily skin.


-Zinc Gluconate can be used for:
*Zinc deficiency symptoms
*Wound healing and skin ulcers, acne treatment and hair loss
*To increase sperm count & motility
*To boost the immune system; zinc plays a major role as an immune enhancer against all viruses and other micro-organisms
*To cut short the common cold and diarrhea
*To support the senses of taste and smell, boost brain activity and enhance memory
*To support normal growth and development
*Zinc Gluconate 76 mg supplies the body with 11 mg of elemental Zinc which is considered the highest concentration Zinc found in one tablet.


-Accelerating wound healing:
Zinc supplements and products are often used to treat skin ulcers, burns, and injuries, as zinc maintains the integrity of the skin.
Zinc is known to be essential in every phase of the wound healing process, from injury right through to repair/remodeling.


-Decreasing inflammation:
Zinc has several antioxidant and anti-inflammatory effects, including reducing oxidative stress.
Oxidative stress is responsible for the development of chronic diseases such as cancer, cardiovascular disease, hypertension, diabetes mellitus, neurodegenerative diseases, rheumatoid arthritis, and more.
Therefore, researchers suggest that zinc supplementation may potentially prove to be a useful intervention to assist.
May potentially delay the progression of age-related macular degeneration and vision loss
Studies have shown that zinc could delay the progression of age-related macular degeneration and vision loss.
Another study of the elderly population in the Netherlands also showed that a high dietary intake of beta carotene, vitamins C and E, and zinc was associated with a substantially reduced risk of age-related macular degeneration.


-May help treat acne:
Some clinical studies suggest that both topical and oral zinc treatments can effectively treat acne.
It is thought that zinc:
*Reduces inflammation:
Inhibits the growth of specific bacteria, which cause acne.
Suppress oily gland activity.
May reduce the severity and duration of cold symptoms
Several studies have shown that zinc potentially reduces cold symptoms.
For example, one study found that zinc lozenges were associated with reduced duration and severity of cold symptoms.
Another review also concluded that zinc lozenges or syrup are beneficial in reducing the duration and severity of cold symptoms when started within 24 hours.

If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you.
It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate).
However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.

As for smearing zinc gluconate all over your face, it is also not a bad idea.
Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types.
It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase.
So great for skin types in need of healing and soothing.



KEY BENEFITS OF ZINC GLUCONATE:
*Zinc Gluconate helps to maintain valuable nutritional support for the immune system, prostate, and eyes
*This essential mineral, Zinc Gluconate, is a crucial component of the body’s primary antioxidant enzymes
*Zinc Gluconate helps support healthy immune system functions
*Zinc Gluconate supports healthy neurological functions
*Zinc Gluconate helps to regulate the blood glucose level of the body



WHAT ARE SOME POTENTIAL BENEFITS OF ZINC GLUCONATE?
Zinc is found in every cell in the human body and is required for the activity of about 100 enzymes.
The potential benefits of zinc gluconate include:
*Supporting your immune system
*Zinc plays an essential role in the immune system, and severe zinc deficiency suppresses your immune function.
*Zinc is needed to develop and activate T-lymphocytes (important white blood cells of the immune system).



THE IMPORTANCE OF ZINC GLUCONATE FOR PREVENTING THE COMMON COLD:
Two of the most important components for the protection of health by defending the immune system in humans are Vitamin C and Zinc.
Cold diseases caused by insufficient intake of these compounds and elements cause great losses and economic problems for societies.
Both substances have been used separately for a very long time and have been studied in the field of pharmacology and dietary supplements.
The products prepared by combining Ascorbic Acid (Vitamin C) and Zinc Gluconate showed its effect within 5 days of the disease when applied to patients with colds.
Zinc Gluconate has been found that this method is more effective than other applications.
In addition, Zinc Gluconate has been understood that the symptoms that are indicative of the disease are resolved in a shorter time.
As a result, Zinc Gluconate has been determined that a good zinc supplement (Zinc Gluconate, Zinc Sulphate ) and Ascorbic Acid (Vitamin C) modification will be important in preventing the disease of this contagious viral disease.



WHAT ABOUT THE GLUCONATE PART?
Zinc Gluconate is there to promote the absorption and bioavailability of zinc and also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).



PHYSICAL and CHEMICAL PROPERTIES of ZINC GLUCONATE:
Chemical formula: C12H22O14Zn
Molar mass: 455.685 g/mol
Melting point: 172 to 175 °C (342 to 347 °F; 445 to 448 K)
Molecular Weight: 455.7
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 14
Rotatable Bond Count: 8
Exact Mass: 454.030097
Monoisotopic Mass: 454.030097
Topological Polar Surface Area: 283 Ų
Heavy Atom Count: 27
Formal Charge: 0
Complexity: 165
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 8
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Molecular Formula: C12H22O14Zn
Melting Point: 131ºC
Flash Point: 375.2ºC
Appearance: In its pure form, it is a white to off-white powder
Storage Keep tightly closed in a cool place in a tightly closed container.
HS Code: 2918160000
Log P: -7.14290
PSA: 254.9
RTECS: ZH3750000
Stability: Stable.
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 172 - 175 °C - lit.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: Powder
Color: White
Molecular weight: 455.7 g/mol
Theoretical zinc content: 14.35%
Soluble in Water: Water solubility (20°C) 100 g/L
Practically insoluble in Ethanol
Insoluble in Acetone, chloroform and toluene



FIRST AID MEASURES of ZINC GLUCONATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC GLUCONATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC GLUCONATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC GLUCONATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC GLUCONATE:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Store under inert gas.
hygroscopic
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of ZINC GLUCONATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Gluconic Acid Zinc Salt
Zinc Gluconate Hydrate
Zinc Gluconate (USP)
pentahydroxyhexanoate
4468-02-4
Zinc(II) Gluconate
Zinc source
D-Gluconate
D-Gluconic Acid
Zinc Gluconate Anhydrate
ZINC GLUCONATE
4468-02-4
Zincgluconate
Zincum gluconicum
Gluconic acid zinc complex
Zinc D-gluconate (1:2)
Bis(D-gluconato-O1,O2) zinc
Gluconic Acid Zinc(II) Salt
Zinc gluconate (USP)
U6WSN5SQ1Z
Zinc, bis(D-gluconato-kappaO1,kappaO2)-, (T-4)-
Gluconic acid zinc
Zinc(II) Gluconate
SCHEMBL21280
CHEMBL3833377
CHEBI:29708
DTXSID20894125
AKOS015951235
DB11248
G0277
D02390
F71322
A826659
Q-201160
Q3822815
Zinc(II) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
zinc (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
Zinc gluconate hydrate
Zinegluconate
Rubozinc
GLUCONIC ACID ZINC SALT
Gluconic Acid Zinc(II) Salt
Zinc(II) gluconate hydrate


ZINC GLYCINATE
ZINC LACTATE N° CAS : 16039-53-5 Nom INCI : ZINC LACTATE Nom chimique : Zinc dilactate N° EINECS/ELINCS : 240-178-9 Classification : Règlementé Compatible Bio (Référentiel COSMOS) Restriction en Europe : III/24 Ses fonctions (INCI) Déodorant : Réduit ou masque les odeurs corporelles désagréables
ZINC LACTATE
ZINC LAURATE N° CAS : 2452-01-9 Nom INCI : ZINC LAURATE Nom chimique : Zinc dilaurate N° EINECS/ELINCS : 219-518-5 Ses fonctions (INCI) Anti Agglomérant : Permet d'assurer la fluidité des particules solides et de limiter leur agglomération dans des produits cosmétiques en poudre ou en masse dure Opacifiant : Réduit la transparence ou la translucidité des cosmétiques Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ZINC LAURATE
ZINC MYRISTATE N° CAS : 16260-27-8 Nom INCI : ZINC MYRISTATE Nom chimique : Zinc dimyristate N° EINECS/ELINCS : 240-369-7 Ses fonctions (INCI) Anti Agglomérant : Permet d'assurer la fluidité des particules solides et de limiter leur agglomération dans des produits cosmétiques en poudre ou en masse dure Opacifiant : Réduit la transparence ou la translucidité des cosmétiques Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ZINC MYRISTATE
SYNONYMS Zinc white; Zinc flowers ; C.I. pigment white 4; ZnO; CAS NO. 1314-13-2
ZINC N, N-DI-N-BUTYLDITHIOCARBAMATE/DI-N-BUTYLAMINE COMPLEX (ZDBCX)

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a complex compound recognized for its role as an ultra-accelerator in rubber processing.
The chemical formula of ZDBCX reveals its unique composition, involving zinc, dibutylamine, and dithiocarbamate moieties.
In its liquid state, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) presents itself as a light brown, slightly turbid liquid.
When encountered, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) emits a faint odor reminiscent of dibutylamine, providing a distinctive olfactory cue.

CAS Number: 136-23-2
EC Number: 205-232-8



APPLICATIONS


Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) serves as a crucial ultra-accelerator in rubber processing, finding widespread applications in the rubber industry.
In natural rubber and SBR formulations, ZDBCX acts as a versatile accelerator, contributing to the efficient curing of rubber compounds.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is specifically valued for its ability to be active at room temperature, streamlining rubber processing procedures.
Transparent and translucent articles benefit significantly from ZDBCX, where it enhances the curing process and maintains color stability.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the preparation of dry mixes, cements, and latex products, showcasing its adaptability in different rubber applications.
Its ultra-accelerating properties make ZDBCX a vital component in the manufacturing of tires, conveyor belts, seals, and various rubber products.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) can be used as a booster for thiazoles, offering compatibility with other rubber accelerators to achieve optimal performance.
In cements, ZDBCX acts as a liquid miscible with rubber solvents, simplifying the preparation process and ensuring even distribution in the final product.

Its addition at the solution stage in cements eliminates the need for incorporation on the mixing mill, streamlining production procedures.
ZDBCX exhibits a short pot-life in finished cements, indicating its rapid curing capabilities and requiring careful handling during application.

The accelerator is used in dry natural rubber processing, where its low-temperature properties and compatibility with milling processes make it valuable.
Extrusion of rubber mixes containing ZDBCX is feasible without scorching, showcasing its suitability for various processing methods.

Hot air curing of rubber mixes with ZDBCX is achieved at relatively low temperatures, contributing to energy-efficient production.
Footwear applications, such as soles, benefit from ZDBCX in translucent SBR compounds, where it enhances curing processes.
ZDBCX can be combined with sulphenamide or thiazole accelerators in translucent SBR compounds for optimal curing results.

The accelerator system with ZDBCX and sulphenamide or thiazole is well-suited for the production of high-quality footwear components.
The use of ZDBCX in rubber formulations contributes to the overall performance, durability, and quality of the final rubber products.

Its applications extend to the preparation of latex products, where it facilitates the curing process and imparts desirable properties to the finished items.
ZDBCX is employed in the manufacturing of rubber goods where transparency or translucency is a desired feature, such as certain seals or gaskets.

The complex's ability to be further activated by Z.I.X. broadens its application scope, providing additional flexibility in rubber processing.
ZDBCX plays a role in minimizing curing times in various rubber applications, enhancing production efficiency.

When incorporated in specific proportions, ZDBCX accelerates the curing of rubber compounds, contributing to shorter processing times.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) contributes to the production of high-quality rubber products with desirable physical and chemical properties.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX)'s compatibility with different rubber types, including natural rubber, SBR, and latex, makes it a versatile choice for various formulations.
Its applications span a range of industries, emphasizing its significance as a key component in rubber processing for diverse end-use products.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is extensively utilized in the production of rubber seals and gaskets due to its efficient curing properties and non-staining characteristics.
Its compatibility with different rubber matrices makes ZDBCX a preferred choice for the manufacturing of a variety of rubber components.
In the automotive industry, ZDBCX finds application in the formulation of rubber parts such as bushings, grommets, and vibration isolators.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX)'s ability to impart transparency to rubber compounds makes it valuable in the production of clear or lightly colored rubber products.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the preparation of rubber belts, where its curing capabilities contribute to the strength and durability of the final product.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a key ingredient in the manufacturing of conveyor belts, providing accelerated curing for improved processing efficiency.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is used in the production of rubber hoses, ensuring quick curing times and enhancing the overall performance of the hoses.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubber sheets, contributing to faster curing and improved properties of the final material.
In the construction industry, ZDBCX is utilized in rubberized asphalt for improved performance, durability, and curing efficiency.

Rubber rollers used in various industrial applications benefit from the accelerated curing provided by ZDBCX in the rubber compound.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the formulation of rubber gloves, where its non-staining properties are crucial for maintaining product aesthetics.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a role in the production of rubberized fabrics, contributing to the material's enhanced strength and curing characteristics.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the manufacturing of rubberized footwear, ensuring rapid curing for efficient production processes.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the formulation of rubberized adhesives, where its properties contribute to quick curing and strong adhesive bonds.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the production of rubberized coatings, providing accelerated curing for enhanced coating performance.
In the electrical industry, ZDBCX is used in the formulation of rubber insulating materials, ensuring efficient curing and product reliability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a crucial component in the production of rubber seals for windows and doors, contributing to the longevity and performance of the seals.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a role in the manufacturing of rubberized sports equipment, ensuring rapid curing and improved material properties.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) contributes to the production of rubberized footwear components, such as insoles and outsoles, with desirable curing characteristics.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the formulation of rubberized linings for tanks and containers, providing enhanced resistance and efficient curing.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the production of rubberized rollers for printing presses, ensuring quick curing and prolonged durability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the formulation of rubberized automotive parts, contributing to the efficiency and reliability of these components.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the production of rubberized medical devices, where quick curing times are critical for efficient manufacturing.

In the aerospace industry, ZDBCX finds applications in the formulation of rubber components for aircraft, ensuring efficient curing and performance.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the manufacturing of rubberized industrial belts, providing accelerated curing for improved processing efficiency and longevity.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a key ingredient in the production of rubberized automotive hoses, ensuring quick and efficient curing for reliable performance.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the formulation of rubberized engine mounts and bushings, contributing to enhanced durability and vibration damping.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the manufacturing of rubberized industrial seals, providing accelerated curing for improved sealing properties.

In the production of rubberized footwear, such as shoe soles, ZDBCX plays a vital role in ensuring fast curing and high-quality end products.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the formulation of rubberized conveyor belts, contributing to rapid curing and increased strength for material transport applications.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the production of rubberized rollers for printing and laminating processes, ensuring quick curing and prolonged durability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds use in the formulation of rubberized marine components, contributing to efficient curing and improved resistance to environmental factors.

In the electronics industry, ZDBCX is employed in the production of rubberized components for electronic devices, ensuring quick curing and reliability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is used in the formulation of rubberized expansion joints, providing accelerated curing for improved flexibility and durability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a role in the manufacturing of rubberized belting for industrial machinery, ensuring rapid curing for increased operational efficiency.
In the production of rubberized gaskets and seals for pipelines, ZDBCX contributes to quick curing and effective sealing properties.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubberized inflatable products, ensuring fast curing for the production of airtight and durable items.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the production of rubberized seals for hydraulic and pneumatic systems, ensuring efficient curing and reliable performance.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the formulation of rubberized agricultural components, contributing to quick curing and increased resilience in the field.
In the textile industry, ZDBCX is employed in the production of rubberized fabric for various applications, ensuring accelerated curing and improved strength.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a crucial role in the formulation of rubberized roof membranes, contributing to quick curing and enhanced weather resistance.
The complex is utilized in the production of rubberized power transmission belts, ensuring rapid curing for efficient energy transfer in machinery.

In the production of rubberized industrial gloves, ZDBCX contributes to quick curing times, essential for high-volume manufacturing processes.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubberized medical tubing and hoses, ensuring efficient curing for the production of reliable medical devices.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the manufacturing of rubberized rollers for material handling and processing equipment, ensuring quick curing and extended service life.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is used in the formulation of rubberized tank linings, contributing to rapid curing and increased resistance to chemical substances.
In the production of rubberized vibration isolators and mounts, ZDBCX ensures quick curing and effective damping properties.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the formulation of rubberized components for sports equipment, contributing to quick curing and enhanced durability.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the production of rubberized shock absorbers, ensuring rapid curing for efficient automotive suspension systems.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubberized coatings for industrial applications, contributing to quick curing and enhanced protective properties.



DESCRIPTION


Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a complex compound recognized for its role as an ultra-accelerator in rubber processing.
The chemical formula of ZDBCX reveals its unique composition, involving zinc, dibutylamine, and dithiocarbamate moieties.
In its liquid state, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) presents itself as a light brown, slightly turbid liquid.

When encountered, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) emits a faint odor reminiscent of dibutylamine, providing a distinctive olfactory cue.
Storage stability is a notable characteristic of ZDBCX, exhibiting good resilience if kept in cool and dry conditions within sealed containers.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) boasts non-discoloring and non-staining properties, making it valuable for applications requiring color stability.

With a minimum purity of 97%, ZDBCX assures a high level of chemical integrity in its composition.
Solubility in aliphatic and aromatic hydrocarbons, coupled with potential emulsification in water, highlights the versatility of ZDBCX in various formulations.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds utility as an accelerator in natural rubber and SBR, particularly in the preparation of dry mixes, cements, and latex products.

Its ultra-accelerating properties make ZDBCX active at room temperature, facilitating efficient rubber curing processes.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) can be further activated by Z.I.X., enhancing its accelerating capabilities in rubber applications.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) serves as an effective booster for thiazoles, demonstrating compatibility with other rubber accelerators.
Transparent and translucent articles derived from both latex and dry rubber benefit significantly from the use of ZDBCX in their formulation.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is composed of intricate molecular structures, contributing to its unique performance characteristics.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) exhibits favorable handling properties in cements, being miscible in all proportions with rubber solvents.

Its addition at the solution stage eliminates the need for incorporation on the mixing mill during cement preparation.
The finished cement, when accelerated by ZDBCX, features a short pot-life, necessitating careful management during application.

In cements, ZDBCX showcases its effectiveness with recommended sulfur dosages and accelerant proportions.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) proves advantageous in dry natural rubber processing, offering a low-temperature acceleration option with the ability to be milled without decomposition.

Extrusion of rubber mixes containing Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is achievable without scorching, provided appropriate precautions are observed.
Curing of rubber mixes containing ZDBCX can be accomplished in hot air at relatively low temperatures, adding to its versatility.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) demonstrates its prowess as an accelerator in translucent SBR compounds, contributing to the curing of applications like footwear soles.

Synergistic combinations with sulphenamide or thiazole accelerators enhance ZDBCX's effectiveness in curing rubber compounds.
For optimal results, recommended levels of ZDBCX are specified for various rubber applications, ensuring precise and efficient performance.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX)'s characteristics, spanning odor, appearance, stability, and reactivity, collectively position ZDBCX as a valuable component in the rubber industry.



PROPERTIES


Physical Properties:

Appearance: Light brown, slightly turbid liquid.
Odor: Faint smell of dibutylamine.
State: Liquid at room temperature.


Chemical Properties:

Chemical Formula: ((n-C4H9)2NCSS)2Zn/(n-C4H9)2NH
Solubility: Soluble in aliphatic and aromatic hydrocarbons; can be emulsified in water.
Purity: 97% minimum.



FIRST AID


Inhalation:

Move the affected person to fresh air.
If breathing is difficult, administer artificial respiration.
Seek medical attention.


Skin Contact:

Remove contaminated clothing.
Wash the affected area with plenty of water for at least 15 minutes.
If irritation persists, seek medical attention.
Contaminated clothing should be laundered before reuse.


Eye Contact:

Rinse eyes thoroughly with water for at least 15 minutes, holding eyelids open.
Seek immediate medical attention.
Remove contact lenses if easily removable after the initial rinse.


Ingestion:

Do not induce vomiting unless directed by medical personnel.
Rinse the mouth with water, but do not swallow.
Seek immediate medical attention.
If vomiting occurs and the person is conscious, keep the head lower than the chest to prevent aspiration.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves and safety goggles or a face shield.
Use respiratory protection if there is a risk of inhalation exposure.

Ventilation:
Work in a well-ventilated area, or use local exhaust ventilation to control airborne concentrations.

Avoidance of Contact:
Avoid skin contact and inhalation of vapors or dust.
Wash hands thoroughly after handling.

Prevention of Ingestion:
Do not eat, drink, or smoke in areas where the substance is handled.
Wash hands before eating, drinking, or smoking.

Handling Procedures:
Follow good industrial hygiene practices.
Use non-sparking tools to avoid ignition in potentially explosive atmospheres.

Storage of Containers:
Keep containers tightly closed when not in use to prevent contamination or evaporation.

Avoidance of Mixing:
Avoid mixing with incompatible materials. Consult the SDS for compatibility information.

Emergency Procedures:
Be familiar with emergency procedures, including the location of emergency exits and the use of emergency equipment.


Storage:

Storage Area:
Store in a cool, dry, and well-ventilated area.
Keep away from incompatible materials and sources of heat or ignition.

Temperature Control:
Store at temperatures recommended by the manufacturer.

Container Compatibility:
Use containers made of materials compatible with the substance.
Check for leaks or damage in storage containers.

Separation:
Store away from food, beverages, and animal feed.
Separate from incompatible materials.

Labeling:
Ensure that containers are properly labeled with the correct product information.

Access Control:
Limit access to storage areas to authorized personnel.

Handling Precautions:
Implement handling precautions based on the physical and chemical properties of the substance.

Special Considerations:
If applicable, follow any special storage conditions recommended by the manufacturer.



SYNONYMS


ZDBC
Zinc dibutyldithiocarbamate
Di-n-butyldithiocarbamic acid zinc salt complex with di-n-butylamine
ZBDCX
Zinc bis(di-n-butyldithiocarbamate)
ZINC OMADINE
Zinc omadine is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.
Zinc omadine is a coordination complex of zinc.
Zinc omadine is chemical compound used as an antifungal and antibacterial agent.
Zinc omadine is a chemical with antifungal and antimicrobial properties.


CAS Number: 13463-41-7
EC Number: 236-671-3
Chemical formula: C10H8N2O2S2Zn


Zinc omadine is a chemical among the pyrithione complex compounds of Zinc Bromide.
Zinc omadine, which has many names, was first reported in the 1930s.
Zinc omadine features two pyridine-derived chelating ligands bound to zinc via oxygen and sulfur atoms.
Zinc omadine was first described in the 1930s.


Zinc omadine is a zinc complex of pyrithione.
Zinc omadine possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc omadine dispersion is a higher viscosity, fine particle dispersion specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


In particular, soluble iron can react with the Zinc omadine active ingredient and a grayblue color may develop.
By using Zinc omadine Dispersion in these formulations, reaction of iron with the zinc pyrithione component is eliminated.
The Zinc omadine Dispersion is registered with the United States Environmental Protection Agency.
While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc omadine has been reported for decades.


Zinc omadine is not shown to have any significant estrogenic activity according to the in vivo and in vitro assays.
Zinc omadine is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.
We do not recommend long-term storage for the solution, please use it up soon.


Zinc omadine is an aromatic zinc compound.
When used as an active drug ingredient, the established name for Zinc omadine is Pyrithione Zinc.
Zinc omadine is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Zinc omadine products are highly active, broad spectrum antimicrobial agents that are registered around the world for use in both personal care as well as industrial product applications.


Zinc omadine fungicide-algaecide is the active ingredient in some of the leading antidandruff shampoo products around the world, and its proven combination of efficacy and safety-in-use has made it the world's leading anti-dandruff agent for more than 30 years.
Zinc omadine fungicide-algaecide is listed in the FDA Final Monograph on Dandruff and Seborrheic Dermatitis as a Category I substance (i.e. generally recognized as safe and effective).


Zinc omadine products are available in Industrial and Cosmetic grades, and in powder and in dispersion forms.
In the U.S., Zinc omadine products are approved for use by the EPA and allowed by the FDA.
Zinc omadine fungicide-algaecide is the zinc complex of pyrithione.
Zinc omadine, the zinc salt of pyrithione (pyridine-2-thiol-1-oxide), has recently been reclassified.



USES and APPLICATIONS of ZINC OMADINE:
Zinc omadine acts as an anti-dandruff and antimicrobial agent. Suitable for personal cleansing with bar soaps.
Zinc omadine is an effective bactericidal and/ or bacteriostatic active against specific bacteria linked to odor.
Zinc omadine is used in anti-dandruff shampoos, rinse-off personal cleansing and other hair care products.


Zinc omadine is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc omadine products have been providing dandruff relief and improved scalp health for over 50 years.
Zinc omadine is used as anti-dandruff agent and bactericide in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.


Zinc omadine is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Zinc omadine has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
Zinc omadine is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Zinc omadine is an effective broad spectrum bio-cide for the preservation of products against spoilage from fungi, yeasts, algae and bacteria.
Zinc omadine is the technical grade active substance more commonly named zinc pyrithione.
Zinc omadine offers antimicrobial protection in the wet and in the dry film state.
Zinc omadine is used in both personal care and industrial product applications.


The recommended applications of Zinc omadine are water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc omadine has a broad antimicrobial spectrum of efficacy against various microorganisms such as bacteria, fungi, and algae.
The outstanding properties of Zinc omadine with regard to effectiveness and compatibility are widely used.
Zinc omadine is a preservative against bacteria, fungi, and yeast.


Zinc omadine is useful in gels, creams, heavy lotions, and talcum powder.
Zinc omadine antimicrobial products are highly active, broad-spectrum biocides used in personal care as well as industrial applications.
Zinc omadine products are approved for OEKO-TEX standard 100, classes I-IV.


Zinc omadine is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.
Zinc omadine, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.


In the crystalline state, Zinc omadine exists as a centrosymmetric dimer.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc omadine is used to treat dandruff and seborrheic dermatitis.
Zinc omadine is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc omadine mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth 1.


Due to low solubility, Zinc omadine released from the topical formulations is deposited and retained relatively well onto the target skin surfaces 2.
These properties include conductivity, corrosion resistance, density, hardness, and impact resistance.
First of all, metal sheets are thermal conductors.


Therefore, sheets with low conductivity are ideal for insulation, while those with high conductivity are used in applications like refrigeration.
Zinc omadine is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Secondly, Zinc omadine is essential to consider the density of the metal plate because it will determine how much a component of a specific size will weigh.
This property is vital in the aerospace and automotive industry, where weight matters.
Moreover, corrosion resistance of a zinc omadine is also essential.


This is because some metal sheets can withstand harsh environmental conditions while others cannot.
Therefore, the sheet you select should fit your needs.
The other property to consider impacts resistance.
If the sheet is likely to be subjected to vigorous collision and shock, you need to pick one with high resistance.


Furthermore, metal hardness also matters because it determines the ability of a sheet to resist the pressure exerted on its surface.
There are three types of hardness; Rockwell, Brinell, and Vickers.
Therefore, the metal plate you select should have the hardness you require.
Antifungal, antibacterial and antiseborrheic agent is used in many shampoos and hair creams.


Zinc omadine, also commonly known as zinc pyrithione, has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc omadine can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.
As the name suggests, Zinc omadine is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.


Zinc omadine's properties are inhibited in formulations containing edta and products containing nonionic chemicals.
This is because chelation or anti-extraction property occurs and the chelated complexes formed do not dissolve.
Zinc omadine is an antifungal and antimicrobial agent that blocks the transport of membranes.
Zinc omadine is the chemical that prevents the formation of mold caused by gram positive and gram negative bacteria in the hair.


In the cosmetic industry, Zinc omadine is used in the production of shampoos that strengthen and rejuvenate hair and prevent graying of hair.
Zinc omadine is used to prevent the formation of bacteria in the paint.
Zinc omadine is used to destroy such fungi in order to prevent the formation of dandruff fungi in the hair.
Zinc omadine also has low irritant properties.


These boats are coated in order to prevent the adhesion of microorganisms that damage the boats and affect their performance.
Zinc omadine is used as a biocide in the dyes used in these coatings .
Zinc omadine prevents the formation of fungi by interfering with the primary proton pump.
Blackmail is an important component for regulating the keratin structure.


Zinc omadine is traded using the range of 1%-2%.
Zinc omadine prevents the formation of bacteria and algae in outdoor paints.
Zinc omadine is a coordination complex of zinc and pyrithione that is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.


-Uses of Zinc omadine:
*Creams and lotions
*Hair products (Head & Shoulders)
*Shampoos


-Cosmetic Uses of Zinc omadine:
*antidandruff agents
*antiseborrhoeic agents
*hair conditioning
*preservatives


-Medical:
Zinc omadine is best known for its use in treating dandruff and seborrheic dermatitis.
Zinc omadine also has antibacterial properties and is effective against many pathogens from the streptococcus and staphylococcus class.
Zinc omadine's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atypical dermatitis, tinea, and vitiligo.
Zinc omadine is approved for over-the-counter topical use in the United States as a treatment for dandruff.
Zinc omadine is the active ingredient in several anti-dandruff shampoos such as Head & Shoulders.
However, in its industrial forms and strengths, it may be harmful by contact or ingestion.


-In paint:
Due to its low solubility in water (8 ppm at neutral pH), Zinc omadine is suitable for use in outdoor paints and other products that provide protection against mildew and algae.
Zinc omadine is an effective algaecide.
Zinc omadine is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc omadine is used in latex paints and the water contains high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed.
Zinc omadine's decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight.


-In sponges:
Zinc omadine is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.


-Zinc omadine shampoo:
Zinc omadine shampoo is found in many common anti-dandruff shampoos.
Zinc omadine is antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Applications of Zinc omadine:
*Beauty & Care
Hair Care, Treatment Products, Skin Care


-Hair Care Applications:
*Anti-Dandruff Products
*Hair Conditioner
*Shampoos & Rinses


-Zinc omadine cream:
Seborrheic dermatitis often affects the scalp, but Zinc omadine can also cause rough, scaly patches on the skin.
Zinc omadine cream is used to treat seborrheic dermatitis or psoriasis on the body.
For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc omadine followed by a moisturizer.
You can also use the cream daily by applying it in a thin layer to the affected area.


-Zinc omadine face wash:
Zinc omadine face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc omadine can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc omadine may help clear acne.


-Medicine:
Zinc omadine can be used to treat dandruff and seborrhoeic dermatitis.
Zinc omadine also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc omadine's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint:
Because of its low solubility in water (8 ppm at neutral pH), Zinc omadine is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc omadine is an algaecide.
Zinc omadine is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc omadine is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc omadine is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.


-Clothing:
A process to apply Zinc omadine to cotton with washable results was patented in the United States in 1984.
Zinc omadine is used to prevent microbe growth in polyester.
Textiles with applied Zinc omadine protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.



FEATURES AND BENEFITS OF ZINC OMADINE:
*Anti-Bacterial
*Anti-Dandruff
*Anti-Fungal
*Antimicrobial
*Chelating
*De-Odorizing
*Odor Masking
*Scalp Protection Effect
*Sebum Control
*Stress Reducing
*Substantivity
*Suitable for Oily Skin



BENEFITS OF ZINC OMADINE:
*Outstanding durability and effectiveness
*Broad spectrum of efficacy against bacteria, and fungi
*Long-lasting material protection, e.g., against rotting
*High wash resistance
*Ease of application in the usual application processes
*Readily combined with many textile effects, e.g., fluorocarbons
*Can be added to a dye bath



COSMETIC INGREDIENTS FUNCTIONS OF ZINC OMADINE:
*Anti-Dandruff Agent
*Antimicrobial Agent
*Bacteriostatic Agent
*Fungistatic Agent



STRUCTURE OF THE ZINC OMADINE:
Zinc omadine ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc omadine exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.
In solution, however, the dimers dissociate via scission of one Zn-O bond.



ZINC OMADINE IS PARTICULARLY EFFECTIVE AS A SINGLE ACTIVE DRY-FILM PRESERVATIVE FOR:
– Architectural and industrial paint and coatings.
– Construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds.
– Building materials including ceilings, ceiling tiles, walls and internal partitions.
– Textiles including apparel and home textiles.
– Thermoplastic polymers such as PVC, silicone, polyolefin, polyurethane and acrylics.
– Plastics applications for the control of mildew and bacteria in carpeting, carpet underlay, cushion and mattress foam, athletic flooring and mats, components of footwear and sponges.



KEY PRODUCT ATTRIBUTES FOR ZINC OMADINE:
Relieves flaking symptoms of dandruff
Targets scalp with a slow release for highest efficacy
Effective dispersion because it is not soluble
Enhances substantivity to the skin and hair
Maintains efficacy over long-term use without resistance



WHAT ARE ZINC OMADINE'S PHYSICAL AND CHEMICAL PROPERTIES?
Zinc omadine is in the form of a cloudy white powder.
Zinc omadine's Melting Point is about 240 °C.
Zinc omadine's density at 25 °C is 1.782 g/cm³.
Zinc omadine emits toxic fumes when heated with heat.
These emit fumes of nitrogen oxides, zinc oxide and sulfur oxide.
Zinc omadine has low resolution. Polyethylene Glycol (PEG400) has a solubility of 2g/kg.
The pH range of Zinc omadine is between 4.5 and 9.5.



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN ZINC OMADINE?
*Cream
*Household Products
*Shampoos



WHERE IS ZINC OMADINE FOUND?
Zinc omadine is an antibacterial and antifungal agent.
Zinc omadine is found in dandruff shampoo and cosmetic products for the treatment of skin problems.



MECHANISM OF ZINC OMADINE:
Zinc omadine's antifungal effect most likely lies in the ability of an un-ionized pyrithione molecule to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.
Fungi are capable of inactivating pyrithione in low concentrations.



MECHANISM OF ACTION OF ZINC OMADINE:
Zinc omadine's antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



HOW IS ZINC OMADINE PRODUCED?
Production of Zinc omadine A compound consisting of 2-Bromopyridine N-oxide or 2-chloropyridine group is selected.
To this selected aqueous solution, one of the Sodium Hydrosulfite, sodium carbonate and sodium hydroxide bases is added.
In the base addition process here, the temperature ranges from 20 °C to 65 °C.
The sodium pyrithione obtained in the production process is increased from 75 °C to 105 °C and reacted with a zinc salt.
The zinc salt used here is zinc chloride (ZnCl 2 ) or zinc sulfate (ZnSO 4 ) .



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE:
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C - OECD Test Guideline 102
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C - OECD Test Guideline 105
Partition coefficient: n-octanol/water: log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
Appearance: beige fine granules (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 240.00 °C. @ 760.00 mm Hg (est)
Boiling Point: 350.20 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000091 mmHg @ 25.00 °C. (est)
Flash Point: 330.00 °F. TCC ( 165.60 °C. ) (est)
logP (o/w): -0.900 (est)
Soluble in: water, 4.876e+005 mg/L @ 25 °C (est)

Water Solubility: 0.068 mg/mL
logP: 0.6
logP: 0.2
logS: -3.7
pKa (Strongest Acidic): 6.84
pKa (Strongest Basic): 0.66
Physiological Charge: -1
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 0
Polar Surface Area: 26.94 Å2
Rotatable Bond Count: 0
Refractivity: 31.64 m3·mol-1
Polarizability: 11.91 Å3
Number of Rings: 2
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule:No



FIRST AID MEASURES of ZINC OMADINE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of ZINC OMADINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
bis(2-pyridylthio)zinc 1,1´-dioxide
bis-(1-hydroxy-2(1H)-pyridinethionato-O,S)zine
De-Squaman
Vancide ZP
Zinc pyrithione
Zinc pyridinethione
Zinc omadine
Pyrithion-Zink
Zinc omadine
Zinc pyridinethione
Zinc Pyrithione
Zinc-2-pyridinethione-1-oxide
Zincpolyanemine
Zinc omadine
bis(2-pyridylthio)zinc 1,1'-dioxide
bis-(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc
De-Squaman; Vancide ZP
Zinc pyridinethione
Zinc omadine
Zinc pyridine-2-thiol-1-oxide
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-
bis(2-pyridylthio)zinc, N,N'-dioxide
bis(1-hydroxy-2(1H)-pyridinethionato)zinc
2-pyridinethiol-1-oxide, zinc salt
vancide p
2-mercaptopyridine-1-oxide zinc salt
zinc 1-hydroxy-2-pyridine-thione
omadine zinc
OM-1563
Pyridinethiol-1-oxide, zinc salt
Zinc-pyrion
Zinc 1-hydroxypyridine-2-thione
Zinc 2-mercaptopyridine-N-oxide
Zinc 2-pyridinethiol-1-oxide
Zinc polyanemine
Zinc PT
Zinc, bis(2-pyridylthio)-, N,N,'-dioxide
ZNPT
Pyrithione zinc.
Zinc pyridinethione
2-Mercaptopyridine N-Oxide Zinc Salt
Mercaptopyridine N-oxide zinc salt
1-Hydroxypyridine-2-thione zinc salt
Bis(2-pyridylthio) Zinc 1,1'-Dioxide
2-Pyridinethiol 1-Oxide Zinc Salt
bis(N-oxopyridine-2-thionato)zinc(II)
Zinc omadine
Zinc Pt
Zinc Pyridine-2-thiol,1-oxide
Zinc bis(2-pyridylthio)-N-oxide
2-mercaptopyridine 1-oxide zinc salt
Zincpolyanemine
Zinc Omadine
2-Mercaptopyridine 1-oxide Zinc Salt
2-Pyridinethiol 1-oxide Zinc Salt
2-Pyridinethiol N-oxide Zinc Salt
2-Pyridylthiol-1-oxide Zinc Salt
AF-Z
BC-J
Biocut ZP
Bis(1-hydroxy-2(1H)-pyridinethionato)zinc
Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc
Bis(2-pyridinethiol 1-oxide)zinc
Clean-Bio ZP
Danex
Marukacide YP-DP
Microban Additive ZO 1
Microban Z 01
NSC 290409;
Niccanon SKT
Niccanon ZP
OM 1563
Omadine Zinc
Pyrithione zinc
SR-A 103
Sanaizol 200
Sanitized TH 22-27
Sanitized TH 27-24BT
Zinc Omacide ZOE
Zinc Omadine
Zinc Omadine ZOE
(T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc
(T-4)-bis(1-hydroxy-2(1H)- pyridinethionato-O,S)zinc
1-hydroxypyridine-2-thione
2(1H)-Pyridinethione, 1-hydroxy-, zinc complex
2-Mercaptopyridine 1-oxide zinc salt
2-Pyridinethiol-1-oxide, zinc salt
2C5H4NOS.Zn
BC-J
Biocut ZP
Bis(1-hydroxy-2(1H)-pyridinethionato)zinc
Bis(2-pyridinethiol-1-oxide)zinc
Bis(2-pyridylthio)zinc 1,1'-dioxide
Breck One Dandruff Shampoo
Evafine P 50
FSB 8332
Finecide ZPT
HEAD & SHOULDERS CONDITIONER
HEAD AND SHOULDERS CONDITIONER
Head and Shoulders
Hokucide ZPT
Mercaptopyridine-N-oxide
Niccanon SKT
OM-1563
Omadine Zinc
Piritionato cincico
Pyrithione zincique
Pyrithionum zincicum
Tomicide Z 50
Tomicide ZPT 50
Top Brass
Vancide P
Vancide ZP
Wella Crisan
ZNP bar
ZPT
Zinc - pyrion
Zinc 1-hydroxy-2-pyridinethione
Zinc 2-mercaptopyridine N-oxide
Zinc 2-pyridinethiol-1-oxide
Zinc Omadine
Zinc bis(2-pyridylthio)-N-oxide
Zinc pt
Zinc pyrethion
Zinc pyridine-2-thiol 1-oxide
Zinc pyridine-2-thiol-1-oxide
Zinc pyridinethione;Zinc, bis(1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2)-, (T-4)-
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)- (8CI)
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4)-
Zinc, bis(2-pyridinylthio)-, N,N'-dioxide
Zinc, bis(2-pyridylthio)-, 1,1'-dioxide
Zinc, bis(2-pyridylthio)-, N,N'-dioxide
Zinc, bis[1-(hydroxy-.kappa.O)-2(1H)-pyridinethionato-.kappa.S2]-, (T-4)-
Zinci pyrithionum
Zincpolyanemine
Zn - pyrion
ZnPT
bis(N-oxopyridine-2-thionato)zinc (II)
zinc bis(2-thioxopyridin-1(2H)-olate)

ZINC OMADINE (ZnPT, ZINC PYRITHIONE)
Zinc Omadine (ZnPT, Zinc Pyrithione) is a “coordination complex” of zinc and pyrithione.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a fine beige granules.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the active ingredient in several anti-dandruff shampoos.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn



Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT, Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc,



Zinc Omadine (ZnPT, Zinc Pyrithione) can restrain and sterilize eight moulds, including black mold,aspergillus flavus, aspergillus versicolor,penicillium citrinum, paecilomium varioti bainier,trichoderma viride, chaetomium globasum and cladosporium herbarum; five bacteria, such as E.coli, staphylococcus aureus, bacillus subtilis,bacillus megaterium and pseudomonas fluorescence as well as two yeast fungi which are distillery yeast and bakers’ yeast.


Zinc Omadine (ZnPT, Zinc Pyrithione) also works against dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a potent antifungal agent in a water suspension format.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and bacterial (gram-positive & gram-negative).


Zinc Omadine (ZnPT, Zinc Pyrithione) is a “coordination complex” of zinc and pyrithione.
Zinc Omadine (ZnPT, Zinc Pyrithione) is one of the active ingredients we use in our shampoos.
On the 4th March 2020, the Scientific Committee on Consumer Safety concluded that Zinc Omadine (ZnPT, Zinc Pyrithione) is safe when used as an anti-dandruff in rinse-off hair products in a concentration of maximum 1%.


Being subject to several safety evaluations, Zinc Omadine (ZnPT, Zinc Pyrithione) was previously found safe as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.
This came as a result of a safety dossier that was submitted by Cosmetics Europe to demonstrate the safety of Zinc Omadine (ZnPT, Zinc Pyrithione) as anti-dandruff in rinse-off hair products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a fine beige granules.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.


Although the exact mechanism of action remains to be fully elucidated, Zinc Omadine (ZnPT, Zinc Pyrithione) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.
Zinc Omadine (ZnPT, Zinc Pyrithione) has also started to be used as an active substance in boat hull paint.


Topical Zinc Omadine (ZnPT, Zinc Pyrithione) appears to be a safe and effective treatment for psoriasis.
An aerosol preparation of Zinc Omadine (ZnPT, Zinc Pyrithione) (0.25%) in a vehicle containing isopropyl myristate appears to be a safe and effective treatment for psoriasis.


Zinc Omadine (ZnPT, Zinc Pyrithione) was found to be negative in mutation tests in bacteria and Chinese hamster ovary cells.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the active ingredient in several anti-dandruff shampoos.


Zinc Omadine (ZnPT, Zinc Pyrithione) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.
UV light slowly breaks down Zinc Omadine (ZnPT, Zinc Pyrithione), providing years of protection even in direct sunlight.


Zinc Omadine (ZnPT, Zinc Pyrithione) is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is approved for over-the-counter topical use in the United States as a treatment for dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the active ingredient in several anti-dandruff shampoos.


The effectiveness of Zinc Omadine (ZnPT, Zinc Pyrithione) is well-established, but as with many modern medicines that have evolved from time-tested remedies, the way the drug actually works is less clear.
In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.


Zinc Omadine (ZnPT, Zinc Pyrithione) has been the top choice among anti-dandruff agents around the world for more than 30 years.
Zinc Omadine (ZnPT, Zinc Pyrithione)'s potent action against Pityrosporum Ovale, the primary culprit for dandruff, ensures healthy, dandruff-free hair.
Unlike other treatments, Zinc Omadine (ZnPT, Zinc Pyrithione) also keeps fungal infections at bay, resulting in a scalp that's not just visibly clean, but truly healthy.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a chemical compound of zinc.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an antifungal and antibacterial agent.
Zinc is a metallic element with the atomic number 30.


If Zinc Omadine (ZnPT, Zinc Pyrithione) is used as a preservative in cosmetic and hygiene products the total proportion can be no more than 0,5 %.
Similarly, no chromosomal aberration was observed in human lymphocytes incubated in vitro in the presence of Zinc Omadine (ZnPT, Zinc Pyrithione) or in lymphocytes harvested from monkeys.


The mineralization of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-on (DCOI) and Zinc Omadine (ZnPT, Zinc Pyrithione) was examined in laboratory tests with marine coastal sediments.
Zinc Omadine (ZnPT, Zinc Pyrithione) has been used as a booster biocide in antifouling paints of ships.


For its environmental risk assessment, a direct analyzing technique of Zinc Omadine (ZnPT, Zinc Pyrithione) has been developed using HPLC-MS without transforming to other substances.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an antifungal and antibacterial agent.


Zinc Omadine (ZnPT, Zinc Pyrithione) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Omadine (ZnPT, Zinc Pyrithione) works against the viability of bacteria and fungi.



USES and APPLICATIONS of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Zinc Omadine (ZnPT, Zinc Pyrithione) is known for its ability to control and prevent dandruff and other scalp conditions caused by the overgrowth of certain microorganisms.
Additionally, Zinc Omadine (ZnPT, Zinc Pyrithione) can be found in skincare products to address other skin conditions like acne and seborrheic dermatitis due to its antimicrobial properties.


Zinc Omadine (ZnPT, Zinc Pyrithione), also known as pyrithione zinc, has antibacterial, antimicrobial, and antifungal qualities that can help cure acne, scalp psoriasis, and seborrheic dermatitis (also known as dandruff).
Zinc Omadine (ZnPT, Zinc Pyrithione) is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.


In recent years, there have been some regulatory updates concerning the use of Zinc Omadine (ZnPT, Zinc Pyrithione) in personal care and cosmetic products in Asia and globally.
Zinc Omadine (ZnPT, Zinc Pyrithione) is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of zinc.
Additionally, Zinc Omadine (ZnPT, Zinc Pyrithione) aids in controlling sebum production, contributing to a healthier scalp environment.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.


Zinc Omadine (ZnPT, Zinc Pyrithione) with a high concentration of 48%.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a biocide that effectively inhibits the growth of fungi and bacteria, making it a popular ingredient in anti-dandruff shampoos and scalp treatments.


Zinc Omadine (ZnPT, Zinc Pyrithione) can stop yeast from growing, which is a major contributor to dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione), as its name implies, is a chemical compound made from zinc and is utilized in a number of hair and skin care products.
Moreover, Zinc Omadine (ZnPT, Zinc Pyrithione) is also allowed in a concentration up to 0.1% in leave-on hair products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.


Zinc Omadine (ZnPT, Zinc Pyrithione) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.


Zinc Omadine (ZnPT, Zinc Pyrithione) is very effective against a wide variety of pathogenic bacteria/fungus.
Sponges: Zinc Omadine (ZnPT, Zinc Pyrithione) is an antibacterial treatment for household sponges, as used by the 3M Corporation.
Zinc Omadine (ZnPT, Zinc Pyrithione) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


In the cosmetic industry, zinc and zinc salts are used in various products.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) has long been used as anti-dandruff agent and widely used in various popular shampoos.


Zinc Omadine (ZnPT, Zinc Pyrithione) is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Omadine (ZnPT, Zinc Pyrithione) can effectively prevent precipitation and double the antimicrobial effect.
Shampoo for dandruff, Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation.


Zinc Omadine (ZnPT, Zinc Pyrithione) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Omadine (ZnPT, Zinc Pyrithione) has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus,playing a role in dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.


As an anti-mildew agent, Zinc Omadine (ZnPT, Zinc Pyrithione) also has some applications on fabrics.
Therefore, Zinc Omadine (ZnPT, Zinc Pyrithione) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


The optimum process conditions were determined by single-factor and orthogonal tests.
The process parameters of cotton fabrics were: Zinc Omadine (ZnPT, Zinc Pyrithione) mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Omadine (ZnPT, Zinc Pyrithione) mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Omadine (ZnPT, Zinc Pyrithione) has unique advantages in environmental friendliness and sterilization persistence.
Therefore, Zinc Omadine (ZnPT, Zinc Pyrithione) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.


Due to its low solubility in water (8 ppm at pH 7), Zinc Omadine (ZnPT, Zinc Pyrithione) is suitable for outdoor coatings and other products that protect against mold and algae.
In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) is an effective algaecide.


Zinc Omadine (ZnPT, Zinc Pyrithione) anti-mildew agent can play the best anti-mildew effect.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an additive to protect paints (such as industrial and marine) against microbe (algal, fungal and bacterial) and crustacean growth.


Zinc Omadine (ZnPT, Zinc Pyrithione) acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.
Zinc Omadine (ZnPT, Zinc Pyrithione) can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.


For shampoo to remove dandruff, Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit the growth of gram-positive and negative bacteria and mold.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.
Zinc Omadine (ZnPT, Zinc Pyrithione) is mainly used in cosmetics, shampoos, and skin care products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is widely used as a fungicide for paints and plastics.
Zinc Omadine (ZnPT, Zinc Pyrithione) can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.


Zinc Omadine (ZnPT, Zinc Pyrithione) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Omadine (ZnPT, Zinc Pyrithione) products have been providing dandruff relief and improved scalp health for over 50 years.


Zinc Omadine (ZnPT, Zinc Pyrithione) is thus used in dandruff shampoos and also in various cosmetics and products against various skin problems.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an antifungal and antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit the growth of yeast, which is a main factor in dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


Zinc Omadine (ZnPT, Zinc Pyrithione) also known as pyrithione zinc, pyrithionium zinc, olmaitin zinc, this zinc complex as early as in the 1930s was synthesized and used as an external antifungal agent or antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is white to yellow crystalline powder at room temperature.


Zinc Omadine (ZnPT, Zinc Pyrithione) is slight characteristic odor.
Zinc Omadine (ZnPT, Zinc Pyrithione) is insoluble in water.
Zinc pyrazide forms insoluble deposits with cationic and non-ionic surfactants and is unstable to light and oxidants, and to acids and bases at higher temperatures.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.
In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) is also used as a cosmetic preservative, oil agent, and paint biocide.


As a fungicide for products such as coatings and plastics, Zinc Omadine (ZnPT, Zinc Pyrithione) is also widely used.
Anti-dandruff agent uses of Zinc Omadine (ZnPT, Zinc Pyrithione): Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)
Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Omadine (ZnPT, Zinc Pyrithione): Skin care (creams & lotions), Foot creams and Talcs


Rinse-off body wash products uses of Zinc Omadine (ZnPT, Zinc Pyrithione): Bar Soaps, Body wash, Bubble bath
Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of zinc.
Although the exact mechanism of action remains to be fully elucidated, Zinc Omadine (ZnPT, Zinc Pyrithione) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.


In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.
As the name suggests, Zinc Omadine (ZnPT, Zinc Pyrithione) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.
Zinc Omadine (ZnPT, Zinc Pyrithione) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.


In the pesticide field, Zinc Omadine (ZnPT, Zinc Pyrithione) is used mainly to control apple leaf curl and scab, among others.
Zinc Omadine (ZnPT, Zinc Pyrithione)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.


Zinc Omadine (ZnPT, Zinc Pyrithione)’s an ingredient in skincare and hair products because of its antibacterial, antimicrobial, and antifungal properties.
Zinc Omadine (ZnPT, Zinc Pyrithione) helps prevent the dandruff-causing microbe, Malassezia globosa, from making the substances that irritate your scalp.
The cosmetic ingredient Zinc Omadine (ZnPT, Zinc Pyrithione) is frequently used in the formulation of hair conditioners, shampoos, face powders, cleansing products, eyeliners and skin care products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is currently regulated as a preservative in rinse-off products (with the exception of oral hygiene products) in a concentration of up to 0.5% in general products and up to 1.0% in hair products.
Zinc Omadine (ZnPT, Zinc Pyrithione) is one of the zinc salts frequently used in hair conditioners, shampoos, face powders, cleaning products, eye pencils, cleaning and skin care products.


It is active against the bacteria E. coli, Zinc Omadine (ZnPT, Zinc Pyrithione) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.
Formulations containing Zinc Omadine (ZnPT, Zinc Pyrithione) have been used in the treatment of dandruff.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a preservative against bacteria, fungi, and yeast.
Zinc Omadine (ZnPT, Zinc Pyrithione) is unstable in light and in the presence of oxidizing agents.
Zinc Omadine (ZnPT, Zinc Pyrithione) is useful in gels, creams, heavy lotions, and talcum powder.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.
The chemical formula of Zinc Omadine (ZnPT, Zinc Pyrithione) is C10H8N2O2S2Zn.


Zinc Omadine (ZnPT, Zinc Pyrithione) is anticipated to be ingested in significant quantities during the production of grooming items such soap and shower products, disinfectants, and antiseptic products.
As a result, Zinc Omadine (ZnPT, Zinc Pyrithione)'s consumption is predicted to increase at a significant rate, expanding the market size.


Zinc Omadine (ZnPT, Zinc Pyrithione) is used Shampoo for dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.


Zinc Omadine (ZnPT, Zinc Pyrithione) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Omadine (ZnPT, Zinc Pyrithione) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .


-Paint uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Omadine (ZnPT, Zinc Pyrithione) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an algaecide.

Zinc Omadine (ZnPT, Zinc Pyrithione) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Omadine (ZnPT, Zinc Pyrithione) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Omadine (ZnPT, Zinc Pyrithione) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.


-Clothing uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
A process to apply Zinc Omadine (ZnPT, Zinc Pyrithione) to cotton with washable results was patented in the United States in 1984.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Omadine (ZnPT, Zinc Pyrithione) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Shampoo uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Zinc Omadine (ZnPT, Zinc Pyrithione) shampoo is found in many common anti-dandruff shampoos.
Zinc Omadine (ZnPT, Zinc Pyrithione) is antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Cream uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Seborrheic dermatitis often affects the scalp, but Zinc Omadine (ZnPT, Zinc Pyrithione) can also cause rough, scaly patches on the skin.
Zinc Omadine (ZnPT, Zinc Pyrithione) cream is used to treat seborrheic dermatitis or psoriasis on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Omadine (ZnPT, Zinc Pyrithione) followed by a moisturizer.
You can also use the cream daily by applying it in a thin layer to the affected area.


-Face wash uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Zinc Omadine (ZnPT, Zinc Pyrithione) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Omadine (ZnPT, Zinc Pyrithione) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Omadine (ZnPT, Zinc Pyrithione) may help clear acne.


-Medicine uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Zinc Omadine (ZnPT, Zinc Pyrithione) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Omadine (ZnPT, Zinc Pyrithione) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Omadine (ZnPT, Zinc Pyrithione)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.



ORIGIN OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Zinc Omadine (ZnPT, Zinc Pyrithione) is synthesized through a multistep chemical process. Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Omadine (ZnPT, Zinc Pyrithione) undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Omadine (ZnPT, Zinc Pyrithione) is then filtered, washed, and dried to obtain a fine powder.



ALTERNATIVES OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
*KETOCONAZOLE,
*SELENIUM SULFIDE



WHAT IS ZINC OMADINE (ZnPT, ZINC PYRITHIONE) USED FOR?
Zinc Omadine (ZnPT, Zinc Pyrithione) is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, Zinc Omadine (ZnPT, Zinc Pyrithione) effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Omadine (ZnPT, Zinc Pyrithione) also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Omadine (ZnPT, Zinc Pyrithione)’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



WHAT DOES ZINC OMADINE (ZnPT, ZINC PYRITHIONE) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



SHAMPOO ZINC OMADINE (ZnPT, ZINC PYRITHIONE) MARKET: OVERVIEW
Zinc Omadine (ZnPT, Zinc Pyrithione), also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by Zinc Omadine (ZnPT, Zinc Pyrithione).
Zinc Omadine (ZnPT, Zinc Pyrithione), as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Omadine (ZnPT, Zinc Pyrithione) shampoo.
Zinc Omadine (ZnPT, Zinc Pyrithione) is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



STRUCTURE OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Omadine (ZnPT, Zinc Pyrithione) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via scission of one Zn-O bond.
Zinc Omadine (ZnPT, Zinc Pyrithione) was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



ADVANTAGES OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Zinc Omadine (ZnPT, Zinc Pyrithione) helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Zinc Omadine (ZnPT, Zinc Pyrithione) is used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



ZINC OMADINE (ZnPT, ZINC PYRITHIONE) THE WORLD'S NUMBER ONE ANTI-DANDRUFF INGREDIENT?
Zinc Omadine (ZnPT, Zinc Pyrithione), coal tar, salicylic acid… the list goes on.
There are so many ways to treat dandruff – but what makes Zinc

Dandruff treatment can take one of two approaches:
*treat the symptoms – this is designed to address the visible symptoms like flakes or inflammation.
However, theunderlying cause of dandruff is still working away.

*tackle the cause – here you get to the root of the problem.
By tackling the cause you can achieve more completerelief and prevent the symptoms from reappearing, so it’s a good long-term solution.
Meet the products that just treat the symptoms of dandruff

Those dandruff treatments that merely work on the symptoms include coal tar and salicylic acid.
Coal tar helps to control the skin’s reaction to scalp irritants formed as the microbe Malassezia globosa breaks down naturaloils on the scalp.
So while you might not experience quite as much irritation, those substances are still being produced at the same rate... and could still damage your scalp.

Salicylic acid acts on the actual flakes.
It is designed to help break the bonds between dead skin cells to make them easier to washoff.

But just like coal tar, salicylic acid doesn’t tackle the underlying cause of your itch, irritation, or flakes – so it’s lesseffective against dandruff.
In fact, in clinical testing these products are far less effective at treating flakes than 1% Zinc Omadine (ZnPT, Zinc Pyrithione) shampoos.



FUNCTIONS OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
*To combat dandruff,
*To control sebum production,
*Zinc Omadine (ZnPT, Zinc Pyrithione) helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Omadine (ZnPT, Zinc Pyrithione) prevents the development of microorganisms in cosmetic products.
*According to the SCCS (Scientific Committee on Consumer Safety) opinion published in 2014 and 2018, Zinc Omadine (ZnPT, Zinc Pyrithione) was found safe to use as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.



WHERE IS ZINC OMADINE (ZnPT, ZINC PYRITHIONE) FOUND?
Zinc Omadine (ZnPT, Zinc Pyrithione) is an antibacterial and antifungal agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an antibacterial and antifungal agent.

Zinc Omadine (ZnPT, Zinc Pyrithione) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Omadine (ZnPT, Zinc Pyrithione) products have been providing dandruff relief and improved scalp health for over 50 years.



FUNCTIONS AND PROPERTIES OF
*Mechanism of Pyrithione-Induced Membrane
*Depolarization in Neurospora crassa
*A clinically controled prospective study with histology
*Embryotoxicity of the antifouling biocide zinc pyrithione to sea urchin (Paracentrotus lividus) and mussel (Mytilus edulis)



ZINC OMADINE (ZnPT, ZINC PYRITHIONE), A BETTER LONG-TERM SOLUTION?
Zinc Omadine (ZnPT, Zinc Pyrithione) is used easily the best way to treat dandruff and keep it away for good is to use an anti-dandruff shampoo with an activeingredient that tackles the root cause of dandruff.

That’s where Zinc Omadine (ZnPT, Zinc Pyrithione) comes in.
Zinc Omadine (ZnPT, Zinc Pyrithione) both removes and helps prevent the formation of scalp irritants, to keep your scalphealthy and comfortable.

With smaller particles, the dandruff-fighting active can:
*give longer lasting protection – because it’s smaller, Zinc Omadine (ZnPT, Zinc Pyrithione) goes deeper into the pores, so it doesn’t rinse out and continues to protect you against dandruff long after the shower

*clean better – the small particles help to create more lather as you wash your hair

*leave your hair and scalp healthier – the particles spread more easily across the scalp and stay there for longer, giving your scalp the protection Zinc Omadine (ZnPT, Zinc Pyrithione) needs and allowing your hair to grow from a healthier base



PROPERTIES OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
In the crystalline state, Zinc Omadine (ZnPT, Zinc Pyrithione) exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



BACTERICIDAL MECHANISM OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Omadine (ZnPT, Zinc Pyrithione) varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Omadine (ZnPT, Zinc Pyrithione) is not the same as that of many bactericides, as it kills bacteria without being consumed.



MECHANISM OF ACTION OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Zinc Omadine (ZnPT, Zinc Pyrithione)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



PREPARATION OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Method 1:
The principle of preparation is that ZnSO4•7H2O reacts with SPT to produce Zinc Omadine (ZnPT, Zinc Pyrithione) and sodium sulfate.
Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.

The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain Zinc Omadine (ZnPT, Zinc Pyrithione) crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Omadine (ZnPT, Zinc Pyrithione) powder.

Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.

Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.

Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Omadine (ZnPT, Zinc Pyrithione) with a yield of about 75%.



SHAMPOO ZINC OMADINE (ZnPT, ZINC PYRITHIONE) MARKET: OVERVIEW
The demand for Zinc Omadine (ZnPT, Zinc Pyrithione) from the intended end use industries is anticipated to drive market expansion.
One of the main factors influencing Zinc Omadine (ZnPT, Zinc Pyrithione)'s growth is the usage of antibacterial coating in numerous applications, including the food and beverage, textile, and paint and coating sectors for anti-bacterial activity.
A further important element that has been thought to propel the growth of the worldwide Zinc Omadine (ZnPT, Zinc Pyrithione) market is the expansion and increased demand for personal care products.



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811

Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble

Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature:
No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C

Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate



FIRST AID MEASURES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC OMADINE (ZOE)
Zinc Omadine (ZOE) is a white to slight yellow powder
Zinc Omadine (ZOE) is a coordination complex of zinc.
Zinc Omadine (ZOE) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn



SYNONYMS:
Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT, Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc,bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-,(T-4)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-,(T-4)-, 2(1H)-Pyridinethione,1-hydroxy-,zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc, Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc,bis(2-pyridinylthio)-,N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione,zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, 1192-70-7, 1320-68-9, 3138-01-0, 3590-23-6, 3865-77-8, 14376-32-0, 15686-64-3, 16782-00-6, 17652-47-0, 31089-48-2, 35430-20-7, 39412-61-8, 51148-10-8, 51406-57-6, 55172-61-7, 74261-71-5, 109702-19-4, 118480-78-7, 162400-43-3, 186322-74-7, 192458-89-2, 208398-70-3, 226883-65-4, 244778-79-8, 266692-38-0, 318995-78-7, 943428-71-5, 1021487-49-9, 1199553-62-2, 1323439-04-8, 2173031-33-7, 2218447-38-0, Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-, (T-4)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc, Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc, bis(2-pyridinylthio)-, N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione, zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, Zinc bis(2-mercaptopyridine-N-oxide), Zinc Omacide ZOE, FK-C, RUCO-BAC ZPY, Microcare ZP, Neostuf ZP 10, Zinc, bis[(2-pyridinethiol-κS2) 1-oxidato]-, Bis[(2-pyridinethiol-κS2) 1-oxidato]zinc, 2-Pyridinethiol, 1-oxide, zinc salt (2:1), Biomaster 627, ZPT 38, Zinc Omadine FPS, Kopthione, 1-HYDROXY-2-PYRIDINE THIONE, ZN SALT, 1-HYDROXYPYRIDINE-2-THIONE ZINC, 1-HYDROXYPYRIDINE-2-THIONE ZINC SALT, 2-mercaptopyridine-1-oxide zinc salt, 2-MERCAPTOPYRIDINE N-OXIDE ZINC, 2-MERCAPTOPYRIDINE N-OXIDE ZINC SALT, 2-PYRIDINETHIOL 1-OXIDE ZINC SALT, BIS(1-HYDROXY-2(H)-PYRIDINETHIONATO)ZINC, BIS(2-PYRIDYLTHIO) ZINC 1,1'-DIOXIDE, de-squaman, MERCAPTOPYRIDINE N-OXIDE ZINC SALT, N-HYDROXYPYRIDINETHIONE ZINC SALT, OM-1563, omadine zinc, PYRITHIONE, Pyrithione zinc, PYRITHIONE ZINC SALT, SALTPYRITHIONE ZINC, vancide zp, Zinc 1-hydroxypyridine-2-thione



Zinc Omadine (ZOE) is a fungistatic and baceriostatic compound that has a variety of uses.
Zinc Omadine (ZOE) is the most important antidandruf agent in the world, which used for more than 30 years in shampoo.
Zinc Omadine (ZOE) shows excellent inhibiting effect on pytyrosporum ovale that causes dandruff.


Zinc Omadine (ZOE) is a zinc complex of pyrithione.
Zinc Omadine (ZOE) possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc Omadine (ZOE) offers antimicrobial protection in the wet and in the dry film state.


Zinc Omadine (ZOE) is a higher viscosity, fine particle dispersion specifically formulated so as to not discolour due to interactions with various elements that can be present in some paint formulations.
Zinc Omadine (ZOE) is a highly effective broad spectrum biocide for the preservation of industrial products against spoilage from yeasts/moulds (fungi), algae and bacteria.


Zinc Omadine (ZOE) is an aqueous dispersion specifically formulated to be colour-stable in the presence of various elements that may be present in some paint formulations and that interact with the active ingredient.
Soluble iron, in particular, can react with the Zinc Omadine (ZOE), producing a grey-blue discolouration in the paint.


By using Zinc Omadine (ZOE), this interaction with iron is avoided.
Zinc Omadine (ZOE) is the latest addition to our Omadine product line.
Zinc Omadine (ZOE) is a higher viscosity, fine particle dispersion specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


In particular, soluble iron can react with the Zinc Omadine (ZOE) active ingredient and a grayblue color may develop.
By using Zinc Omadine (ZOE) in these formulations, reaction of iron with the zinc pyrithione component is eliminated.
Zinc Omadine (ZOE) is registered with the United States Environmental Protection Agency


Zinc Omadine (ZOE) is a highly active, broad-spectrum antimicrobial biocide, which is a 48% aqueous dispersion of zinc pyrithione.
Zinc Omadine (ZOE) is a white to slight yellow powder
Zinc Omadine (ZOE) is a coordination complex of zinc.


The boiling point of Zinc Omadine (ZOE) is 253.8°C, and Flash point is 107.3°C.
Zinc Omadine (ZOE) is insoluble in water.
Zinc Omadine (ZOE) is renowned for its microbial growth control properties.


Zinc Omadine (ZOE) has a boiling point of 253.8 u00b0C at 760 mmHg.
Zinc Omadine (ZOE) showcases a stable melting point at 262u00b0C
The flash point of Zinc Omadine (ZOE) is calculated at 107.3 u00b0C.


Density 1.782 g/cm3 at 25 u00b0C is the noted density of Zinc Omadine (ZOE).
Zinc Omadine (ZOE)'s solubility is less than 0.1g per 100 mL at 21u00b0C.
Apart from its properties, Zinc Omadine (ZOE) also calls for particular storage considerations.


Zinc Omadine (ZOE) must be kept in tightly sealed containers or cylinders, stored in cool, dry, and dark locations, away from ignition sources and any incompatible materials.
Zinc Omadine (ZOE) is necessary to label the storage area correctly and protect the containers from any physical damage.


Zinc Omadine (ZOE) finds its significance in various endeavors, primarily in the creation of antimicrobial coatings and additives, as well as other medical applications.
Its robust characteristics and versatility make Zinc Omadine (ZOE) a valuable addition to the B2B marketplace.


Zinc Omadine (ZOE) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Zinc Omadine (ZOE) is considered as a coordination complex of zinc.
The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers.


In the crystalline state, Zinc Omadine (ZOE) exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociat
Zinc Omadine (ZOE) is a fine beige granules.


It is a naturally round sand with a Zinc Omadine (ZOE) infused vinyl coating that is effective against bacteria, mold, mildew and algae all while being long-lasting and durable.
Zinc Omadine (ZOE) is non-absorbant and will minimize the associated odors caused by pet urine.



USES and APPLICATIONS of ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.
Zinc Omadine (ZOE) is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Omadine (ZOE) is also often used in kitchen sponges as an antibacterial treatment.
Zinc Omadine (ZOE) has broad spectrum bactericide and marine antifouling material, and is well used for cosmetic, shampoo, skins medicine, adhesive and coating painting and so on.


Zinc Omadine (ZOE) is used created specifically for film protection of coatings.
Zinc Omadine (ZOE) provides superior dry antifungal protection for Lethex paints compared to carbendazim based products.
The active ingredient in Zinc Omadine (ZOE) is also one of the most effective dry algaecides known in the industry.


Along with all types of Zinc Omadine (ZOE) can be used in all types of latex building coatings, both for external and internal applications.
Zinc Omadine (ZOE) is particularly effective as a single active dry film preservative for.
Zinc Omadine (ZOE) is a higher viscosity, fine particle dispersion in water of zinc pyrithione specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


Zinc Omadine (ZOE) is used to inhibit the growth of fungi, both yeasts and molds, the growth of algae, and the growth of a broad spectrum of both Gram positive and Gram negative bacteria.
Zinc Omadine (ZOE) is used in both personal care and industrial product applications.


Zinc Omadine (ZOE) is also used in water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc Omadine (ZOE) is used architectural and industrial paint and coatings
Zinc Omadine (ZOE) is used construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds


Zinc Omadine (ZOE) is used building materials including ceilings, ceiling tiles, walls andinternal partitions
Zinc Omadine (ZOE) is a superordinary anti-scale agent and anti-lipid overflow agent.
Zinc Omadine (ZOE) can effectively eliminate eumycete which produces dandruff, and result in relieving itching, removing dandruff, diminishing phalacrosis and deferring poliosis.


Therefore, Zinc Omadine (ZOE) is considered as a highly effective and safe product.
Zinc Omadine (ZOE) will add the value of shampoo and meet the high demands from consumers.
For this reason, Zinc Omadine (ZOE) is widely used in the production of shampoo.


Moreover, as a fine,broad-spectrum,environment-friendly and low toxic antiseptics, Zinc Omadine (ZOE) can be used in civil coating, adhesive and carpet.
The mixture of Zinc Omadine (ZOE) and Cu2O also can be used as marine antifouling coating to prevent adhering of shells, seaweeds and aquatic organisms to hulls.


Zinc Omadine (ZOE) and its relative products enjoy tremendous potential and broad space in pesticide field with properties of high-efficiency, environmental protection,hypotoxicity and broad-spectrum.
Zinc Omadine (ZOE) is used as anti-dandruff agent and bactericide.


Zinc Omadine (ZOE) is used in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.
Zinc Omadine (ZOE) is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Zinc Omadine (ZOE) has fungistatic (that is,it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.


Zinc Omadine (ZOE) can be used to infill artificial lawns and playgrounds.
Zinc Omadine (ZOE) keeps turf looking new and natural.
Zinc Omadine (ZOE) is well graded to ensure excellent drainage.


Zinc Omadine (ZOE) can be used to protect the surfaces of coatings and other dry films from fungal and algal growth.
In addition, Zinc Omadine (ZOE) can provide good activity against both fungi and algae, offer long-term protection due to its low water solubility, and does not trigger environmental symbol labeling at normal use levels.


Zinc Omadine (ZOE) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Omadine (ZOE) is a useful building block for chemical synthesis.


Zinc Omadine (ZOE) is extremely effective in eliminating the fungi, Malassezia spp., which is directly linked to the scalp condition, dandruff.
An important characteristic of Zinc Omadine (ZOE) is that it is efficacious against numerous other organisms beyond Malassezia, including the various bacteria species associated with producing odor on the skin.


Shampoo for dandruff, Zinc Omadine (ZOE) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation.
Zinc Omadine (ZOE) is also used as a cosmetic preservative, oil, paint biocide.


Zinc Omadine (ZOE) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Omadine (ZOE) is a coordination complex of zinc and pyrithione that has antimicrobial, anticancer, and fungicidal activities.
Zinc Omadine (ZOE) is active against the bacteria E. coli, S. aureus, K. pneumoniae, A. baumannii, P. aeruginosa, E. faecium, E. faecalis, and E. cloacae (MICs = 1-4 µg/ml) and the fungus P. ovale when used at concentrations ranging from 0.01 to 10 µg/ml.


Zinc Omadine (ZOE) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg/kg per week for six weeks.
Topical application of Zinc Omadine (ZOE) completely prevents Aspergillus growth in soy meal-derived adhesives.
Formulations containing Zinc Omadine (ZOE) have been used in the treatment of dandruff and in the prevention of fungal growth in industrial applications.



GENERAL PROPERTIES OF ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) exhibits pronounced growth inhibiting activity against abroad
spectrum of both Gram negative and Gram positive bacteria
Zinc Omadine (ZOE) inhibits the growth of fungi, both yeast and mold
Zinc Omadine (ZOE) is insoluble in water



WHAT DOES ZINC OMADINE (ZOE) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



ALTERNATIVES OF ZINC OMADINE (ZOE):
*KETOCONAZOLE,
*SELENIUM SULFIDE



PROPERTIES OF ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) is a white to slight yellow powder or white suspension
Zinc Omadine (ZOE) is in water Insoluble (Stability SZinc Omadine (ZOE) is s



DISPERSION OF ZINC OMADINE (ZOE):
*is a color stable, fine particle dispersion (in water) of zinc pyrithione
inhibits the growth of fungi, both yeasts and molds.
*inhibits the growth of algae.
*inhibits the growth of a broad spectrum of both Gram positive and Gram negative bacteria.



KEY FEATURES OF ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) is off-white to tan color.
Molecular Weight of Zinc Omadine (ZOE) is 317.69
Zinc Omadine (ZOE) is used found in personal care products like soaps, shampoos, and industrial items such as paints, coatings

Zinc Omadine (ZOE) is a celebrated compound in the chemical industry, celebrated for its unique microbiocidal properties and versatile applications.
Zinc Omadine (ZOE) consists of a pale off-white to tan powder, suitable for various industry applications.
The low solubility of Zinc Omadine (ZOE), along with its impressive stability, makes it an ideal choice for unique solutions in various sectors.



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE (ZOE):
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811

Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble

Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature:
No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C

Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate



FIRST AID MEASURES of ZINC OMADINE (ZOE):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE (ZOE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE (ZOE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE (ZOE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE (ZOE):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC OMADINE (ZOE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC OMADINE ZOE ANTIMICROBIAL
Zinc Omadine ZOE Antimicrobial is a zinc complex of pyrithione.
Zinc Omadine ZOE Antimicrobial is a white to slight yellow powder.
Zinc Omadine ZOE Antimicrobial is a coordination complex of zinc.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn



SYNONYMS:
Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc, bis(2-pyridinylthio)-, N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione, zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, Zinc bis(2-mercaptopyridine-N-oxide), Zinc Omacide ZOE, FK-C, RUCO-BAC ZPY, Microcare ZP, Neostuf ZP 10, Zinc, bis[(2-pyridinethiol-κS2) 1-oxidato]-, Bis[(2-pyridinethiol-κS2) 1-oxidato]zinc, 2-Pyridinethiol, 1-oxide, zinc salt (2:1), Biomaster 627, ZPT 38, Zinc Omadine FPS, Kopthione, 1-HYDROXY-2-PYRIDINE THIONE, ZN SALT, 1-HYDROXYPYRIDINE-2-THIONE ZINC, 1-HYDROXYPYRIDINE-2-THIONE ZINC SALT, 2-mercaptopyridine-1-oxide zinc salt, 2-MERCAPTOPYRIDINE N-OXIDE ZINC, 2-MERCAPTOPYRIDINE N-OXIDE ZINC SALT, 2-PYRIDINETHIOL 1-OXIDE ZINC SALT, BIS(1-HYDROXY-2(H)-PYRIDINETHIONATO)ZINC, BIS(2-PYRIDYLTHIO) ZINC 1,1'-DIOXIDE, de-squaman, MERCAPTOPYRIDINE N-OXIDE ZINC SALT, N-HYDROXYPYRIDINETHIONE ZINC SALT, OM-1563, omadine zinc, PYRITHIONE, Pyrithione zinc, PYRITHIONE ZINC SALT, SALTPYRITHIONE ZINC, vancide zp, Zinc 1-hydroxypyridine-2-thione, Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT, Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc,bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-,(T-4)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-,(T-4)-, 2(1H)-Pyridinethione,1-hydroxy-,zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc, Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc,bis(2-pyridinylthio)-,N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione,zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, 1192-70-7, 1320-68-9, 3138-01-0, 3590-23-6, 3865-77-8, 14376-32-0, 15686-64-3, 16782-00-6, 17652-47-0, 31089-48-2, 35430-20-7, 39412-61-8, 51148-10-8, 51406-57-6, 55172-61-7, 74261-71-5, 109702-19-4, 118480-78-7, 162400-43-3, 186322-74-7, 192458-89-2, 208398-70-3, 226883-65-4, 244778-79-8, 266692-38-0, 318995-78-7, 943428-71-5, 1021487-49-9, 1199553-62-2, 1323439-04-8, 2173031-33-7, 2218447-38-0, Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-, (T-4)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc,



Zinc Omadine ZOE Antimicrobial is a naturally round sand that is effective against bacteria, mold, mildew and algae all while being long-lasting and durable.
Zinc Omadine ZOE Antimicrobial is non-absorbant and will minimize the associated odors caused by pet urine.
Zinc Omadine ZOE Antimicrobial is a highly active, broad-spectrum zinc complex of pyrithione.


Zinc Omadine ZOE Antimicrobial is a white to slight yellow powder.
Zinc Omadine ZOE Antimicrobial is a coordination complex of zinc.
Zinc Omadine ZOE Antimicrobial is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.


Zinc Omadine ZOE Antimicrobial is a zinc complex of pyrithione.
Zinc Omadine ZOE Antimicrobial is an aqueous dispersion specifically formulated to be colour-stable in the presence of various elements that may be present in some paint formulations and that interact with the active ingredient.


Soluble iron, in particular, can react with the Zinc Omadine ZOE Antimicrobial, producing a grey-blue discolouration in the paint.
Zinc Omadine ZOE Antimicrobial possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc Omadine ZOE Antimicrobial is a zinc complex of pyrithione.


Zinc Omadine ZOE Antimicrobial possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc Omadine ZOE Antimicrobial offers antimicrobial protection in the wet and in the dry film state.
Zinc Omadine ZOE Antimicrobial is a fungistatic and baceriostatic compound that has a variety of uses.


Zinc Omadine ZOE Antimicrobial has a boiling point of 253.8 u00b0C at 760 mmHg.
Zinc Omadine ZOE Antimicrobial showcases a stable melting point at 262u00b0C
The flash point of Zinc Omadine ZOE Antimicrobial is calculated at 107.3 u00b0C.


Density 1.782 g/cm3 at 25 u00b0C is the noted density of Zinc Omadine ZOE Antimicrobial.
Zinc Omadine ZOE Antimicrobial's solubility is less than 0.1g per 100 mL at 21u00b0C.
Apart from its properties, Zinc Omadine ZOE Antimicrobial also calls for particular storage considerations.


Zinc Omadine ZOE Antimicrobial is the most important antidandruf agent in the world, which used for more than 30 years in shampoo.
Zinc Omadine ZOE Antimicrobial shows excellent inhibiting effect on pytyrosporum ovale that causes dandruff.
Zinc Omadine ZOE Antimicrobial offers antimicrobial protection in the wet and in the dry film state.


Zinc Omadine ZOE Antimicrobial is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Zinc Omadine ZOE Antimicrobial is considered as a coordination complex of zinc.
The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers.


The boiling point of Zinc Omadine ZOE Antimicrobial is 253.8°C, and Flash point is 107.3°C.
Zinc Omadine ZOE Antimicrobial is insoluble in water.
Zinc Omadine ZOE Antimicrobial is renowned for its microbial growth control properties.



USES and APPLICATIONS of ZINC OMADINE ZOE ANTIMICROBIAL:
Zinc Omadine ZOE Antimicrobial is used in both personal care and industrial product applications.
The recommended applications of Zinc Omadine ZOE Antimicrobial are water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc Omadine ZOE Antimicrobial is a dry film and in-can preservative for water-based paints.


Zinc Omadine ZOE Antimicrobial is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.
Zinc Omadine ZOE Antimicrobial is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Omadine ZOE Antimicrobial is also used as a dry film preservative for marine anti-fouling paints.
Zinc Omadine ZOE Antimicrobial is a highly active, broad-spectrum zinc complex of pyrithione.
Zinc Omadine ZOE Antimicrobial is also often used in kitchen sponges as an antibacterial treatment.


Zinc Omadine ZOE Antimicrobial has broad spectrum bactericide and marine antifouling material, and is well used for cosmetic, shampoo, skins medicine, adhesive and coating painting and so on.
Zinc Omadine ZOE Antimicrobial is used created specifically for film protection of coatings.


Zinc Omadine ZOE Antimicrobial provides superior dry antifungal protection for Lethex paints compared to carbendazim based products.
The active ingredient in Zinc Omadine ZOE Antimicrobial is also one of the most effective dry algaecides known in the industry.
Zinc Omadine ZOE Antimicrobial is used building materials including ceilings, ceiling tiles, walls andinternal partitions


Zinc Omadine ZOE Antimicrobial is a superordinary anti-scale agent and anti-lipid overflow agent.
Zinc Omadine ZOE Antimicrobial can effectively eliminate eumycete which produces dandruff, and result in relieving itching, removing dandruff, diminishing phalacrosis and deferring poliosis.


Zinc Omadine ZOE Antimicrobial offers very good protection against microbial growth including bacteria, fungi and algae.
Along with all types of Zinc Omadine ZOE Antimicrobial can be used in all types of latex building coatings, both for external and internal applications.
Zinc Omadine ZOE Antimicrobial is particularly effective as a single active dry film preservative for.


Zinc Omadine ZOE Antimicrobial is a higher viscosity, fine particle dispersion in water of zinc pyrithione specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.
Zinc Omadine ZOE Antimicrobial is used to inhibit the growth of fungi, both yeasts and molds, the growth of algae, and the growth of a broad spectrum of both Gram positive and Gram negative bacteria.


Zinc Omadine ZOE Antimicrobial is used in both personal care and industrial product applications.
Zinc Omadine ZOE Antimicrobial is also used in water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc Omadine ZOE Antimicrobial is used architectural and industrial paint and coatings


Zinc Omadine ZOE Antimicrobial is used construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds
Zinc Omadine ZOE Antimicrobial is a higher viscosity, fine particle dispersion specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


Zinc Omadine ZOE Antimicrobial and its relative products enjoy tremendous potential and broad space in pesticide field with properties of high-efficiency, environmental protection,hypotoxicity and broad-spectrum.
Zinc Omadine ZOE Antimicrobial is used as anti-dandruff agent and bactericide.


Zinc Omadine ZOE Antimicrobial helps prevent growth of bacteria, mold and mildew.
Therefore, Zinc Omadine ZOE Antimicrobial is considered as a highly effective and safe product.
Zinc Omadine ZOE Antimicrobial will add the value of shampoo and meet the high demands from consumers.


For this reason, Zinc Omadine ZOE Antimicrobial is widely used in the production of shampoo.
Moreover, as a fine,broad-spectrum,environment-friendly and low toxic antiseptics, Zinc Omadine ZOE Antimicrobial can be used in civil coating, adhesive and carpet.


The mixture of Zinc Omadine ZOE Antimicrobial and Cu2O also can be used as marine antifouling coating to prevent adhering of shells, seaweeds and aquatic organisms to hulls.
Zinc Omadine ZOE Antimicrobial can be used to infill artificial lawns, putting greens, and playgrounds.


Zinc Omadine ZOE Antimicrobial keeps turf looking new and natural.
Zinc Omadine ZOE Antimicrobial is well graded to ensure excellent drainage.
Zinc Omadine ZOE Antimicrobial is used in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.


Zinc Omadine ZOE Antimicrobial is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Zinc Omadine ZOE Antimicrobial has fungistatic (that is,it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.


Zinc Omadine ZOE Antimicrobial can be used to infill artificial lawns and playgrounds.
Zinc Omadine ZOE Antimicrobial keeps turf looking new and natural.
Zinc Omadine ZOE Antimicrobial is well graded to ensure excellent drainage.



GENERAL PROPERTIES OF ZINC OMADINE ZOE ANTIMICROBIAL:
Zinc Omadine ZOE Antimicrobial exhibits pronounced growth inhibiting activity against abroad
spectrum of both Gram negative and Gram positive bacteria
Zinc Omadine ZOE Antimicrobial inhibits the growth of fungi, both yeast and mold
Zinc Omadine ZOE Antimicrobial is insoluble in water



WHAT DOES ZINC OMADINE ZOE ANTIMICROBIAL DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



ALTERNATIVES OF ZINC OMADINE ZOE ANTIMICROBIAL:
*KETOCONAZOLE
*SELENIUM SULFIDE



PROPERTIES OF ZINC OMADINE ZOE ANTIMICROBIAL:
*Non-toxic
*Effective Product
*Superior Quality
*UV Resistant
*Pet Friendly.



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE ZOE ANTIMICROBIAL:
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature:
No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C

Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder

Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17

Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%

Particle size :D70Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811

DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry,
dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic

Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C

PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C



FIRST AID MEASURES of ZINC OMADINE ZOE ANTIMICROBIAL:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE ZOE ANTIMICROBIAL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE ZOE ANTIMICROBIAL:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE ZOE ANTIMICROBIAL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE ZOE ANTIMICROBIAL:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC OMADINE ZOE ANTIMICROBIAL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC OXIDE
DESCRIPTION:

Zinc oxide is a largely inert, white compound which is used very widely as a bulking agent or filler, and as a white pigment.
Zinc oxide is found in some rubber, glass and ceramic products, and finds use in the chemical industry as a catalyst.
Zinc oxide is also used in paints as a corrosion inhibitor and for mildew control.


CAS Number, 1314-13-2
EC Number, 215-222-5


SYNONYMS OF ZINC OXIDE:
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Zinc is an essential trace element, and zinc oxide is added to fertilizers, animal feed, and vitamin supplements.
Zinc oxide is also used in a many cosmetic and medical products and in toiletries, as it has antibacterial and deodorant properties.
Zinc oxide is found in, for example, baby powder and anti-dandruff shampoos, in calamine lotion and in sticking plasters and dental cement.

Its strong absorption of ultra-violet (UV) light has led to its use in sunscreen lotions.
Zinc oxide blocks both UVA (longer wavelength) and UVB (shorter wavelength) radiation, protecting against sunburn, skin damage and cancer.


Zinc oxide is an inorganic compound with the formula ZnO.
Zinc oxide is a white powder that is insoluble in water.

Zinc oxide is used as an additive in numerous materials and products including cosmetics, food supplements, rubbers, plastics, ceramics, glass, cement, lubricants, paints, sunscreens, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, semi conductors, and first-aid tapes.
Although Zinc oxide occurs naturally as the mineral zincite, most zinc oxide is produced synthetically.



Crude zinc oxide is a yellow-gray granular solid with no odor.
Zinc oxide is insoluble in water.
The primary hazard is the threat posed to the environment. Immediate steps should be taken to limit its spread to the environment.
Prolonged inhalation of the dust may result in metal fume fever with symptoms of chills, fever, muscular pain, nausea and vomiting.




Zinc oxide is an inorganic compound used in a number of manufacturing processes.
Zinc oxide can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes.

Zinc oxide occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically.
Zinc oxide is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.






HISTORY OF ZINC OXIDE:
Zinc compounds were probably used by early humans, in processed and unprocessed forms, as a paint or medicinal ointment, but their composition is uncertain.
The use of pushpanjan, probably zinc oxide, as a salve for eyes and open wounds, is mentioned in the Indian medical text the Charaka Samhita, thought to date from 500 BC or before.
Zinc oxide ointment is also mentioned by the Greek physician Dioscorides (1st century AD)

Galen suggested treating ulcerating cancers with zinc oxide, as did Avicenna in his The Canon of Medicine.
Zinc oxide is used as an ingredient in products such as baby powder and creams against diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.

The Romans produced considerable quantities of brass (an alloy of zinc and copper) as early as 200 BC by a cementation process where copper was reacted with zinc oxide.
The zinc oxide is thought to have been produced by heating zinc ore in a shaft furnace.
This liberated metallic zinc as a vapor, which then ascended the flue and condensed as the oxide.

This process was described by Dioscorides in the 1st century AD.
Zinc oxide has also been recovered from zinc mines at Zawar in India, dating from the second half of the first millennium BC.

From the 12th to the 16th century zinc and zinc oxide were recognized and produced in India using a primitive form of the direct synthesis process.
From India, zinc manufacture moved to China in the 17th century. In 1743, the first European zinc smelter was established in Bristol, United Kingdom.

Around 1782 Louis-Bernard Guyton de Morveau proposed replacing lead white pigment with zinc oxide.
The main usage of zinc oxide (zinc white) was in paints and as an additive to ointments.

Zinc white was accepted as a pigment in oil paintings by 1834 but it did not mix well with oil.
This problem was solved by optimizing the synthesis of ZnO.

In 1845, Edme-Jean Leclaire in Paris was producing the oil paint on a large scale, and by 1850, zinc white was being manufactured throughout Europe.
The success of zinc white paint was due to its advantages over the traditional white lead: zinc white is essentially permanent in sunlight, it is not blackened by sulfur-bearing air, it is non-toxic and more economical.

Because zinc white is so "clean" it is valuable for making tints with other colors, but it makes a rather brittle dry film when unmixed with other colors.
For example, during the late 1890s and early 1900s, some artists used zinc white as a ground for their oil paintings.
All those paintings developed cracks over the years.


In recent times, most zinc oxide was used in the rubber industry to resist corrosion.
In the 1970s, the second largest application of ZnO was photocopying.
High-quality ZnO produced by the "French process" was added to photocopying paper as a filler.
This application was soon displaced by titanium


USES OF ZINC OXIDE (ZNO):
Zinc oxide is used as a bulking agent.
Zinc oxide is used as a colourant.
Zinc oxide is used in over-the-counter drug products.

Zinc oxide is used as a skin protectant.
Zinc oxide is used as a sunscreen as it reduces and prevents sunburn.
Zinc oxide is used in preventing premature skin ageing.

Zinc oxide is Used in nail products.
Zinc oxide is used as a diaper rash ointment.



CHEMICAL PROPERTIES OF ZINC OXIDE:
Pure ZnO is a white powder, but in nature it occurs as the rare mineral zincite, which usually contains manganese and other impurities that confer a yellow to red color.

Crystalline zinc oxide is thermochromic, changing from white to yellow when heated in air and reverting to white on cooling.
This color change is caused by a small loss of oxygen to the environment at high temperatures to form the non-stoichiometric Zn1+xO, where at 800 °C, x = 0.00007.


Zinc oxide is an amphoteric oxide.
Zinc oxide is nearly insoluble in water, but it will dissolve in most acids, such as hydrochloric acid:
ZnO + 2 HCl → ZnCl2 + H2O
Solid zinc oxide will also dissolve in alkalis to give soluble zincates:
ZnO + 2 NaOH + H2O → Na2[Zn(OH)4]


ZnO reacts slowly with fatty acids in oils to produce the corresponding carboxylates, such as oleate or stearate.
When mixed with a strong aqueous solution of zinc chloride, ZnO forms cement-like products best described as zinc hydroxy chlorides.
This cement was used in dentistry.


ZnO also forms cement-like material when treated with phosphoric acid; related materials are used in dentistry.
A major component of zinc phosphate cement produced by this reaction is hopeite, Zn3(PO4)2•4H2O.

ZnO decomposes into zinc vapor and oxygen at around 1975 °C with a standard oxygen pressure.
In a carbothermic reaction, heating with carbon converts the oxide into zinc vapor at a much lower temperature (around 950 °C).
ZnO + C → Zn(Vapor) + CO



PHYSICAL PROPERTIES OF ZINC OXIDE:
Structure:
Zinc oxide crystallizes in two main forms, hexagonal wurtzite and cubic zincblende.
The wurtzite structure is most stable at ambient conditions and thus most common.
The zincblende form can be stabilized by growing ZnO on substrates with cubic lattice structure.


In both cases, the zinc and oxide centers are tetrahedral, the most characteristic geometry for Zn(II).
ZnO converts to the rocksalt motif at relatively high pressures about 10 GPa.
Hexagonal and zincblende polymorphs have no inversion symmetry (reflection of a crystal relative to any given point does not transform it into itself).

This and other lattice symmetry properties result in piezoelectricity of the hexagonal and zincblende ZnO, and pyroelectricity of hexagonal ZnO.
The hexagonal structure has a point group 6 mm (Hermann–Mauguin notation) or C6v (Schoenflies notation), and the space group is P63mc or C6v4.
The lattice constants are a = 3.25 Å and c = 5.2 Å; their ratio c/a ~ 1.60 is close to the ideal value for hexagonal cell c/a = 1.633.

As in most group II-VI materials, the bonding in ZnO is largely ionic (Zn2+O2−) with the corresponding radii of 0.074 nm for Zn2+ and 0.140 nm for O2−.
This property accounts for the preferential formation of wurtzite rather than zinc blende structure, as well as the strong piezoelectricity of ZnO.
Because of the polar Zn−O bonds, zinc and oxygen planes are electrically charged.

To maintain electrical neutrality, those planes reconstruct at atomic level in most relative materials, but not in ZnO – its surfaces are atomically flat, stable and exhibit no reconstruction.
However, studies using wurtzoid structures explained the origin of surface flatness and the absence of reconstruction at ZnO wurtzite surfaces in addition to the origin of charges on ZnO planes.


MECHANICAL PROPERTIES OF ZINC OXIDE:
ZnO is a wide-band gap semiconductor of the II-VI semiconductor group.
The native doping of the semiconductor due to oxygen vacancies or zinc interstitials is n-type

ZnO is a relatively soft material with approximate hardness of 4.5 on the Mohs scale.
Its elastic constants are smaller than those of relevant III-V semiconductors, such as GaN.
The high heat capacity and heat conductivity, low thermal expansion and high melting temperature of ZnO are beneficial for ceramics.

The E2 optical phonon in ZnO exhibits an unusually long lifetime of 133 ps at 10 K.
Among the tetrahedrally bonded semiconductors, it has been stated that ZnO has the highest piezoelectric tensor, or at least one comparable to that of GaN and AlN.


This property makes it a technologically important material for many piezoelectrical applications, which require a large electromechanical coupling.
Therefore, ZnO in the form of thin film has been one of the most studied resonator materials for thin-film bulk acoustic resonators.


ELECTRICAL AND OPTICAL PROPERTIES OF ZINC OXIDE:
Favourable properties of zinc oxide include good transparency, high electron mobility, wide band gap, and strong room-temperature luminescence.
Those properties make ZnO valuable for a variety of emerging applications: transparent electrodes in liquid crystal displays, energy-saving or heat-protecting windows, and electronics as thin-film transistors and light-emitting diodes.


ZnO has a relatively wide direct band gap of ~3.3 eV at room temperature.
Advantages associated with a wide band gap include higher breakdown voltages, ability to sustain large electric fields, lower electronic noise, and high-temperature and high-power operation.
The band gap of ZnO can further be tuned to ~3–4 eV by its alloying with magnesium oxide or cadmium oxide.

Due to this large band gap, there have been efforts to create visibly transparent solar cells utilising ZnO as a light absorbing layer. However, these solar cells have so far proven highly inefficient.

Most ZnO has n-type character, even in the absence of intentional doping.
Nonstoichiometry is typically the origin of n-type character, but the subject remains controversial.

An alternative explanation has been proposed, based on theoretical calculations, that unintentional substitutional hydrogen impurities are responsible.
Controllable n-type doping is easily achieved by substituting Zn with group-III elements such as Al, Ga, In or by substituting oxygen with group-VII elements chlorine or iodine.

Reliable p-type doping of ZnO remains difficult.
This problem originates from low solubility of p-type dopants and their compensation by abundant n-type impurities.
This problem is observed with GaN and ZnSe.


Measurement of p-type in "intrinsically" n-type material is complicated by the inhomogeneity of samples.
Current limitations to p-doping limit electronic and optoelectronic applications of ZnO, which usually require junctions of n-type and p-type material.
Known p-type dopants include group-I elements Li, Na, K; group-V elements N, P and As; as well as copper and silver.

However, many of these form deep acceptors and do not produce significant p-type conduction at room temperature.
Electron mobility of ZnO strongly varies with temperature and has a maximum of ~2000 cm2/(V•s) at 80 K.
Data on hole mobility are scarce with values in the range 5–30 cm2/(V•s).

ZnO discs, acting as a varistor, are the active material in most surge arresters.
Zinc oxide is noted for its strongly nonlinear optical properties, especially in bulk.
The nonlinearity of ZnO nanoparticles can be fine-tuned according to their size.


PRODUCTION OF ZINC OXIDE:
For industrial use, ZnO is produced at levels of 105 tons per year by three main processes:

Indirect process:
In the indirect or French process, metallic zinc is melted in a graphite crucible and vaporized at temperatures above 907 °C (typically around 1000 °C).
Zinc vapor reacts with the oxygen in the air to give ZnO, accompanied by a drop in its temperature and bright luminescence.
Zinc oxide particles are transported into a cooling duct and collected in a bag house.

This indirect method was popularized by Edme Jean LeClaire of Paris in 1844 and therefore is commonly known as the French process.
Its product normally consists of agglomerated zinc oxide particles with an average size of 0.1 to a few micrometers.
By weight, most of the world's zinc oxide is manufactured via French process.


Direct process:
The direct or American process starts with diverse contaminated zinc composites, such as zinc ores or smelter by-products.
The zinc precursors are reduced (carbothermal reduction) by heating with a source of carbon such as anthracite to produce zinc vapor, which is then oxidized as in the indirect process.
Because of the lower purity of the source material, the final product is also of lower quality in the direct process as compared to the indirect one.


Wet chemical process:
A small amount of industrial production involves wet chemical processes, which start with aqueous solutions of zinc salts, from which zinc carbonate or zinc hydroxide is precipitated.
The solid precipitate is then calcined at temperatures around 800 °C.


Laboratory synthesis:
The red and green colors of these synthetic ZnO crystals result from different concentrations of oxygen vacancies.
Numerous specialised methods exist for producing ZnO for scientific studies and niche applications.
These methods can be classified by the resulting ZnO form (bulk, thin film, nanowire), temperature ("low", that is close to room temperature or "high", that is T ~ 1000 °C), process type (vapor deposition or growth from solution) and other parameters.


Large single crystals (many cubic centimeters) can be grown by the gas transport (vapor-phase deposition), hydrothermal synthesis,[34][48][49] or melt growth.
However, because of the high vapor pressure of ZnO, growth from the melt is problematic.

Growth by gas transport is difficult to control, leaving the hydrothermal method as a preference.
Thin films can be produced by chemical vapor deposition, metalorganic vapour phase epitaxy, electrodeposition, pulsed laser deposition, sputtering, sol–gel synthesis, atomic layer deposition, spray pyrolysis, etc.


Ordinary white powdered zinc oxide can be produced in the laboratory by electrolyzing a solution of sodium bicarbonate with a zinc anode.
Zinc hydroxide and hydrogen gas are produced.
The zinc hydroxide upon heating decomposes to zinc oxide:
Zn + 2 H2O → Zn(OH)2 + H2
Zn(OH)2 → ZnO + H2O


ZnO nanostructures:
Nanostructures of ZnO can be synthesized into a variety of morphologies including nanowires, nanorods, tetrapods, nanobelts, nanoflowers, nanoparticles etc.
Nanostructures can be obtained with most above-mentioned techniques, at certain conditions, and also with the vapor–liquid–solid method.

The synthesis is typically carried out at temperatures of about 90 °C, in an equimolar aqueous solution of zinc nitrate and hexamine, the latter providing the basic environment.
Certain additives, such as polyethylene glycol or polyethylenimine, can improve the aspect ratio of the ZnO nanowires.

Doping of the ZnO nanowires has been achieved by adding other metal nitrates to the growth solution.
The morphology of the resulting nanostructures can be tuned by changing the parameters relating to the precursor composition (such as the zinc concentration and pH) or to the thermal treatment (such as the temperature and heating rate).

Aligned ZnO nanowires on pre-seeded silicon, glass, and gallium nitride substrates have been grown using aqueous zinc salts such as zinc nitrate and zinc acetate in basic environments.
Pre-seeding substrates with ZnO creates sites for homogeneous nucleation of ZnO crystal during the synthesis.

Common pre-seeding methods include in-situ thermal decomposition of zinc acetate crystallites, spincoating of ZnO nanoparticles and the use of physical vapor deposition methods to deposit ZnO thin films.
Pre-seeding can be performed in conjunction with top down patterning methods such as electron beam lithography and nanosphere lithography to designate nucleation sites prior to growth.
Aligned ZnO nanowires can be used in dye-sensitized solar cells and field emission devices.


APPLICATIONS OF ZINC OXIDE:
The applications of zinc oxide powder are numerous, and the principal ones are summarized below. Most applications exploit the reactivity of the oxide as a precursor to other zinc compounds.
For material science applications, zinc oxide has high refractive index, high thermal conductivity, binding, antibacterial and UV-protection properties.

Consequently, it is added into materials and products including plastics, ceramics, glass, cement, rubber, lubricants, paints, ointments, adhesive, sealants, concrete manufacturing, pigments, foods, batteries, ferrites, fire retardants, etc.


Rubber industry:
Between 50% and 60% of ZnO use is in the rubber industry.
Zinc oxide along with stearic acid is used in the sulfur vulcanization of rubber.
ZnO additives also protect rubber from fungi (see medical applications) and UV light.


Ceramic industry:
Ceramic industry consumes a significant amount of zinc oxide, in particular in ceramic glaze and frit compositions.
The relatively high heat capacity, thermal conductivity and high temperature stability of ZnO coupled with a comparatively low coefficient of expansion are desirable properties in the production of ceramics.

ZnO affects the melting point and optical properties of the glazes, enamels, and ceramic formulations.
Zinc oxide as a low expansion, secondary flux improves the elasticity of glazes by reducing the change in viscosity as a function of temperature and helps prevent crazing and shivering.

By substituting ZnO for BaO and PbO, the heat capacity is decreased and the thermal conductivity is increased.
Zinc in small amounts improves the development of glossy and brilliant surfaces.
However, in moderate to high amounts, it produces matte and crystalline surfaces.
With regard to color, zinc has a complicated influence.

Medicine:
Skin treatment:
Zinc oxide as a mixture with about 0.5% iron(III) oxide (Fe2O3) is called calamine and is used in calamine lotion.
Historically the mineral calamine is a mixture of the oxides zincite and hemimorphite.
Zinc oxide is widely used to treat a variety of skin conditions, including atopic dermatitis, contact dermatitis, itching due to eczema, diaper rash and acne.

Zinc oxide is used in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.
Zinc oxide is often combined with castor oil to form an emollient and astringent, zinc and castor oil cream, commonly used to treat infants.


Zinc oxide is also a component in tape (called "zinc oxide tape") used by athletes as a bandage to prevent soft tissue damage during workouts.

Antibacterial:
Zinc oxide is used in mouthwash products and toothpastes as an anti-bacterial agent proposed to prevent plaque and tartar formation, and to control bad breath by reducing the volatile gases and volatile sulfur compounds (VSC) in the mouth.
Along with zinc oxide or zinc salts, these products also commonly contain other active ingredients, such as cetylpyridinium chloride, xylitol, hinokitiol, essential oils and plant extracts.


Powdered zinc oxide has deodorizing and antibacterial properties.
ZnO is added to cotton fabric, rubber, oral care products, and food packaging.
Enhanced antibacterial action of fine particles compared to bulk material is not exclusive to ZnO and is observed for other materials, such as silver.
This property results from the increased surface area of the fine particles.


Sunscreen:
Zinc oxide is used in sunscreen to absorb ultraviolet light.
It is the broadest spectrum UVA and UVB absorber that is approved for use as a sunscreen by the U.S. Food and Drug Administration (FDA),[84] and is completely photostable.

When used as an ingredient in sunscreen, zinc oxide blocks both UVA (320–400 nm) and UVB (280–320 nm) rays of ultraviolet light.
Zinc oxide and the other most common physical sunscreen, titanium dioxide, are considered to be nonirritating, nonallergenic, and non-comedogenic.
Zinc from zinc oxide is, however, slightly absorbed into the skin.


Many sunscreens use nanoparticles of zinc oxide (along with nanoparticles of titanium dioxide) because such small particles do not scatter light and therefore do not appear white.
The nanoparticles are not absorbed into the skin more than regular-sized zinc oxide particles are, and are only absorbed into the outermost layer of the skin but not into the body.

Dental restoration:
When mixed with eugenol, zinc oxide eugenol is formed, which has applications as a restorative and prosthodontic in dentistry.


Food additive:
Zinc oxide is added to many food products, including breakfast cereals, as a source of zinc, a necessary nutrient.
Zinc sulfate is also used for the same purpose.
Some prepackaged foods also include trace amounts of ZnO even if it is not intended as a nutrient.

Pigment:
Zinc oxide (zinc white) is used as a pigment in paints and is more opaque than lithopone, but less opaque than titanium dioxide.
Zinc oxide is also used in coatings for paper.
Chinese white is a special grade of zinc white used in artists' pigments.

The use of zinc white as a pigment in oil painting started in the middle of 18th century.
Zinc oxide has partly replaced the poisonous lead white and was used by painters such as Böcklin, Van Gogh, Manet, Munch and others.
Zinc oxide is also a main ingredient of mineral makeup (CI 77947).


UV absorber:
Micronized and nano-scale zinc oxide provides strong protection against UVA and UVB ultraviolet radiation, and are consequently used in sunscreens, and also in UV-blocking sunglasses for use in space and for protection when welding, following research by scientists at Jet Propulsion Laboratory (JPL).

Coatings:
Paints containing zinc oxide powder have long been utilized as anticorrosive coatings for metals.
They are especially effective for galvanized iron.
Iron is difficult to protect because its reactivity with organic coatings leads to brittleness and lack of adhesion.
Zinc oxide paints retain their flexibility and adherence on such surfaces for many years.

ZnO highly n-type doped with aluminium, gallium, or indium is transparent and conductive (transparency ~90%, lowest resistivity ~10−4 Ω•cm[97]).
ZnO:Al coatings are used for energy-saving or heat-protecting windows.
The coating lets the visible part of the spectrum in but either reflects the infrared (IR) radiation back into the room (energy saving) or does not let the IR radiation into the room (heat protection), depending on which side of the window has the coating.


Plastics, such as polyethylene naphthalate (PEN), can be protected by applying zinc oxide coating.
The coating reduces the diffusion of oxygen through PEN.
Zinc oxide layers can also be used on polycarbonate in outdoor applications.

The coating protects polycarbonate from solar radiation, and decreases its oxidation rate and photo-yellowing.

Corrosion prevention in nuclear reactors:
Zinc oxide depleted in 64Zn (the zinc isotope with atomic mass 64) is used in corrosion prevention in nuclear pressurized water reactors.
The depletion is necessary, because 64Zn is transformed into radioactive 65Zn under irradiation by the reactor neutrons.

Methane reforming:
Zinc oxide (ZnO) is used as a pretreatment step to remove hydrogen sulfide (H2S) from natural gas following hydrogenation of any sulfur compounds prior to a methane reformer, which can poison the catalyst.
At temperatures between about 230–430 °C (446–806 °F), H2S is converted to water by the following reaction:
H2S + ZnO → H2O + ZnS


Electronics:
Photograph of an operating ZnO UV laser diode and the corresponding device structure.
Flexible gas sensor based on ZnO nanorods and its internal structure.
ITO stands for indium tin oxide and PET for polyethylene terephthalate.

ZnO has wide direct band gap (3.37 eV or 375 nm at room temperature).
Therefore, its most common potential applications are in laser diodes and light emitting diodes (LEDs).
Moreover, ultrafast nonlinearities and photoconductive functions have been reported in ZnO

Some optoelectronic applications of ZnO overlap with that of GaN, which has a similar band gap (~3.4 eV at room temperature).
Compared to GaN, ZnO has a larger exciton binding energy (~60 meV, 2.4 times of the room-temperature thermal energy), which results in bright room-temperature emission from ZnO.

ZnO can be combined with GaN for LED-applications.
For instance, a transparent conducting oxide layer and ZnO nanostructures provide better light outcoupling.
Other properties of ZnO favorable for electronic applications include its stability to high-energy radiation and its ability to be patterned by wet chemical etching.

Radiation resistance makes ZnO a suitable candidate for space applications.
ZnO is the most promising candidate in the field of random lasers to produce an electronically pumped UV laser source.

The pointed tips of ZnO nanorods result in a strong enhancement of an electric field.
Therefore, they can be used as field emitters.


Aluminium-doped ZnO layers are used as transparent electrodes.
The components Zn and Al are much cheaper and less toxic compared to the generally used indium tin oxide (ITO).
One application which has begun to be commercially available is the use of ZnO as the front contact for solar cells or of liquid crystal displays.

Transparent thin-film transistors (TTFT) can be produced with ZnO. As field-effect transistors, they do not need a p–n junction, thus avoiding the p-type doping problem of ZnO.
Some of the field-effect transistors even use ZnO nanorods as conducting channels.

Gas sensors:
Zinc oxide is used in semiconductor gas sensors for detecting airborne compounds such as hydrogen sulfide, nitrogen dioxide, and volatile organic compounds.
ZnO is a semiconductor that becomes n-doped by adsorption of reducing compounds, which reduces the detected electrical resistance through the device, in a manner similar to the widely used tin oxide semiconductor gas sensors.

Zinc oxide is formed into nanostructures such as thin films, nanoparticles, nanopillars or nanowires in order to provide large surface area for interaction with gasses.
The sensors are made selective for specific gasses by doping or surface-attaching materials such as catalytic noble metals.

Piezoelectricity:
The piezoelectricity in textile fibers coated in ZnO have been shown capable of fabricating "self-powered nanosystems" with everyday mechanical stress from wind or body movements.
In 2008 the Center for Nanostructure Characterization at the Georgia Institute of Technology reported producing an electricity generating device (called flexible charge pump generator) delivering alternating current by stretching and releasing zinc oxide nanowires.

This mini-generator creates an oscillating voltage up to 45 millivolts, converting close to seven percent of the applied mechanical energy into electricity.
Researchers used wires with lengths of 0.2–0.3 mm and diameters of three to five micrometers, but the device could be scaled down to smaller size.

In form of a thin film ZnO has been demonstrated in miniaturised high frequency thin film resonators, sensors and filters.



Li-ion battery and supercapacitors:
ZnO is a promising anode material for lithium-ion battery because it is cheap, biocompatible, and environmentally friendly.
ZnO has a higher theoretical capacity (978 mAh g−1) than many other transition metal oxides such as CoO (715 mAh g−1), NiO (718 mAh g−1) and CuO (674 mAh g−1).
ZnO is also used as an electrode in supercapacitors













CHEMICAL AND PHYSICAL PROPERTIES OF ZINC OXIDE:
Chemical formula, ZnO
Molar mass, 81.406 g/mol[1]
Appearance, White solid[1]
Odor, Odorless
Density, 5.6 g/cm3[1]
Melting point, 1,974 °C (3,585 °F; 2,247 K) (decomposes)[1][7]
Boiling point, 2,360 °C (4,280 °F; 2,630 K) (decomposes)
Solubility in water, 0.0004% (17.8°C)[2]
Band gap, 3.2 eV (direct)[3]
Electron mobility, 180 cm2/(V•s)[3]
Magnetic susceptibility (χ), −27.2•10−6 cm3/mol[4]
Thermal conductivity, 0.6 W/(cm•K)[5]
Refractive index (nD), n1=2.013, n2=2.029[6]
Structure[8],
Crystal structure, Wurtzite
Space group, C6v4-P63mc
Lattice constant, a = 3.2495 Å, c = 5.2069 Å
Formula units (Z), 2
Coordination geometry, Tetrahedral
Thermochemistry[9],
Heat capacity (C), 40.3 J•K−1mol−1
Std molar
entropy (S⦵298), 43.65±0.40 J•K−1mol−1
Std enthalpy of
formation (ΔfH⦵298), -350.46±0.27 kJ mol−1
Gibbs free energy (ΔfG⦵), -320.5 kJ mol−1
Enthalpy of fusion (ΔfH⦵fus), 70 kJ/mol
Molecular Weight
81.4 g/mol
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
79.924056 g/mol
Monoisotopic Mass
79.924056 g/mol
Topological Polar Surface Area
17.1Ų
Heavy Atom Count
2
Formal Charge
0
Complexity
2
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
CAS number, 1314-13-2
EC index number, 030-013-00-7
EC number, 215-222-5
Grade, ACS,Reag. Ph Eur
Hill Formula, OZn
Chemical formula, ZnO
Molar Mass, 81.37 g/mol
HS Code, 2817 00 00
Density, 5.61 g/cm³ (20 °C)
Melting Point, 1975 °C
pH value, 7 (50 g/l, H₂O, 20 °C) (slurry)
Bulk density, 200 - 700 kg/m³
Solubility, (20 °C) insoluble
Molecular formula, ZnO
Molar mass, 81.408 g/mol
Appearance, White solid
Odor, odorless
Density, 5.606 g/cm3
Melting point, 1975 °C (decomposes)
Boiling point, 2360 °C
Solubility in water, 0.16 mg/100 mL (30 °C)
Band gap, 3.3 eV (direct)
Refractive index (nD), 2.0041



SAFETY INFORMATION ABOUT ZINC OXIDE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


ZINC OXIDE
Zinc Oxide Zinc Oxide is a wide-band gap semiconductor of the II-VI semiconductor group. The native doping of the semiconductor due to oxygen vacancies or zinc interstitials is n-type. Other favorable properties include good transparency, high electron mobility, wide band gap, and strong room-temperature luminescence. Those properties make ZnO valuable for a variety of emerging applications: transparent electrodes in liquid crystal displays, energy-saving or heat-protecting windows, and electronics as thin-film transistors and light-emitting diodes. Chemical properties of Zinc Oxide Pure Zinc oxide is a white powder, but in nature Zinc oxide occurs as the rare mineral zincite, which usually contains manganese and other impurities that confer a yellow to red color. Crystalline zinc oxide is thermochromic, changing from white to yellow when heated in air and reverting to white on cooling. This color change is caused by a small loss of oxygen to the environment at high temperatures to form the non-stoichiometric Zn1+xO, where at 800 °C, x = 0.00007. Zinc oxide is an amphoteric oxide. It is nearly insoluble in water, but it will dissolve in most acids, such as hydrochloric acid: Zinc oxide + 2 HCl → ZnCl2 + H2O Solid zinc oxide will also dissolve in alkalis to give soluble zincates: Zinc oxide + 2 NaOH + H2O → Na2[Zn(OH)4] Zinc oxide reacts slowly with fatty acids in oils to produce the corresponding carboxylates, such as oleate or stearate. Zinc oxide forms cement-like products when mixed with a strong aqueous solution of zinc chloride and these are best described as zinc hydroxy chlorides. This cement was used in dentistry. Hopeite Zinc oxide also forms cement-like material when treated with phosphoric acid; related materials are used in dentistry. A major component of zinc phosphate cement produced by this reaction is hopeite, Zn3(PO4)2·4H2O. Zinc oxide decomposes into zinc vapor and oxygen at around 1975 °C with a standard oxygen pressure. In a carbothermic reaction, heating with carbon converts the oxide into zinc vapor at a much lower temperature (around 950 °C). Zinc oxide + C → Zn(Vapor) + CO Physical properties of Zinc oxide Zinc oxide crystallizes in two main forms, hexagonal wurtzite and cubic zincblende. The wurtzite structure is most stable at ambient conditions and thus most common. The zincblende form can be stabilized by growing Zinc oxide on substrates with cubic lattice structure. In both cases, the zinc and oxide centers are tetrahedral, the most characteristic geometry for Zn(II). Zinc oxide converts to the rocksalt motif at relatively high pressures about 10 GPa. The many remarkable medical properties of creams containing Zinc oxide can be explained by its elastic softness, which is characteristic of tetrahedral coordinated binary compounds close to the transition to octahedral structures. Hexagonal and zincblende polymorphs have no inversion symmetry (reflection of a crystal relative to any given point does not transform it into itself). This and other lattice symmetry properties result in piezoelectricity of the hexagonal and zincblende Zinc oxide, and pyroelectricity of hexagonal Zinc oxide. The hexagonal structure has a point group 6 mm (Hermann-Mauguin notation) or C6v (Schoenflies notation), and the space group is P63mc or C6v4. The lattice constants are a = 3.25 Å and c = 5.2 Å; their ratio c/a ~ 1.60 is close to the ideal value for hexagonal cell c/a = 1.633. As in most group II-VI materials, the bonding in Zinc oxide is largely ionic (Zn2+–O2−) with the corresponding radii of 0.074 nm for Zn2+ and 0.140 nm for O2−. This property accounts for the preferential formation of wurtzite rather than zinc blende structure, as well as the strong piezoelectricity of Zinc oxide. Because of the polar Zn-O bonds, zinc and oxygen planes are electrically charged. To maintain electrical neutrality, those planes reconstruct at atomic level in most relative materials, but not in Zinc oxide – its surfaces are atomically flat, stable and exhibit no reconstruction. However, studies using wurtzoid structures explained the origin of surface flatness and the absence of reconstruction at Zinc oxide wurtzite surfaces in addition to the origin of charges on Zinc oxide planes. Mechanical properties of Zinc oxide Zinc oxide is a relatively soft material with approximate hardness of 4.5 on the Mohs scale. Its elastic constants are smaller than those of relevant III-V semiconductors, such as GaN. The high heat capacity and heat conductivity, low thermal expansion and high melting temperature of Zinc oxide are beneficial for ceramics. The E2 optical phonon in Zinc oxide exhibits an unusually long lifetime of 133 ps at 10 K. Among the tetrahedrally bonded semiconductors, it has been stated that Zinc oxide has the highest piezoelectric tensor, or at least one comparable to that of GaN and AlN. This property makes it a technologically important material for many piezoelectrical applications, which require a large electromechanical coupling. Therefore Zinc oxide has been in forms of thin film one of the most studied resonator material for thin-film bulk acoustic resonators. Electrical properties of Zinc oxide Zinc oxide has a relatively large direct band gap of ~3.3 eV at room temperature. Advantages associated with a large band gap include higher breakdown voltages, ability to sustain large electric fields, lower electronic noise, and high-temperature and high-power operation. The band gap of Zinc oxide can further be tuned to ~3–4 eV by its alloying with magnesium oxide or cadmium oxide. Most Zinc oxide has n-type character, even in the absence of intentional doping. Nonstoichiometry is typically the origin of n-type character, but the subject remains controversial. An alternative explanation has been proposed, based on theoretical calculations, that unintentional substitutional hydrogen impurities are responsible. Controllable n-type doping is easily achieved by substituting Zn with group-III elements such as Al, Ga, In or by substituting oxygen with group-VII elements chlorine or iodine. Reliable p-type doping of Zinc oxide remains difficult. This problem originates from low solubility of p-type dopants and their compensation by abundant n-type impurities. This problem is observed with GaN and ZnSe. Measurement of p-type in "intrinsically" n-type material is complicated by the inhomogeneity of samples. Current limitations to p-doping limit electronic and optoelectronic applications of Zinc oxide, which usually require junctions of n-type and p-type material. Known p-type dopants include group-I elements Li, Na, K; group-V elements N, P and As; as well as copper and silver. However, many of these form deep acceptors and do not produce significant p-type conduction at room temperature. Electron mobility of Zinc oxide strongly varies with temperature and has a maximum of ~2000 cm2/(V·s) at 80 K. Data on hole mobility are scarce with values in the range 5–30 cm2/(V·s). Zinc oxide discs, acting as a varistor, are the active material in most surge arresters. Production of Zinc oxide For industrial use, Zinc oxide is produced at levels of 105 tons per year by three main processes: Indirect process of Zinc oxide In the indirect or French process, metallic zinc is melted in a graphite crucible and vaporized at temperatures above 907 °C (typically around 1000 °C). Zinc vapor reacts with the oxygen in the air to give Zinc oxide, accompanied by a drop in its temperature and bright luminescence. Zinc oxide particles are transported into a cooling duct and collected in a bag house. This indirect method was popularized by LeClaire (France) in 1844 and therefore is commonly known as the French process. Its product normally consists of agglomerated zinc oxide particles with an average size of 0.1 to a few micrometers. By weight, most of the world's zinc oxide is manufactured via French process. Direct process of Zinc oxide The direct or American process starts with diverse contaminated zinc composites, such as zinc ores or smelter by-products. The zinc precursors are reduced (carbothermal reduction) by heating with a source of carbon such as anthracite to produce zinc vapor, which is then oxidized as in the indirect process. Because of the lower purity of the source material, the final product is also of lower quality in the direct process as compared to the indirect one. Wet chemical process A small amount of industrial production involves wet chemical processes, which start with aqueous solutions of zinc salts, from which zinc carbonate or zinc hydroxide is precipitated. The solid precipitate is then calcined at temperatures around 800 °C. Laboratory synthesis The red and green colors of these synthetic Zinc oxide crystals result from different concentrations of oxygen vacancies. Numerous specialised methods exist for producing Zinc oxide for scientific studies and niche applications. These methods can be classified by the resulting Zinc oxide form (bulk, thin film, nanowire), temperature ("low", that is close to room temperature or "high", that is T ~ 1000 °C), process type (vapor deposition or growth from solution) and other parameters. Large single crystals (many cubic centimeters) can be grown by the gas transport (vapor-phase deposition), hydrothermal synthesis, or melt growth. However, because of high vapor pressure of Zinc oxide, growth from the melt is problematic. Growth by gas transport is difficult to control, leaving the hydrothermal method as a preference. Thin films can be produced by chemical vapor deposition, metalorganic vapour phase epitaxy, electrodeposition, pulsed laser deposition, sputtering, sol-gel synthesis, atomic layer deposition, spray pyrolysis, etc. Ordinary white powdered zinc oxide can be produced in the laboratory by electrolyzing a solution of sodium bicarbonate with a zinc anode. Zinc hydroxide and hydrogen gas are produced. The zinc hydroxide upon heating decomposes to zinc oxide. Zn + 2 H2O → Zn(OH)2 + H2 Zn(OH)2 → Zinc oxide + H2O Zinc oxide nanostructures Nanostructures of Zinc oxide can be synthesized into a variety of morphologies including nanowires, nanorods, tetrapods, nanobelts, nanoflowers, nanoparticles etc. Nanostructures can be obtained with most above-mentioned techniques, at certain conditions, and also with the vapor-liquid-solid method. The synthesis is typically carried out at temperatures of about 90 °C, in an equimolar aqueous solution of zinc nitrate and hexamine, the latter providing the basic environment. Certain additives, such as polyethylene glycol or polyethylenimine, can improve the aspect ratio of the Zinc oxide nanowires. Doping of the Zinc oxide nanowires has been achieved by adding other metal nitrates to the growth solution. The morphology of the resulting nanostructures can be tuned by changing the parameters relating to the precursor composition (such as the zinc concentration and pH) or to the thermal treatment (such as the temperature and heating rate). Aligned Zinc oxide nanowires on pre-seeded silicon, glass, and gallium nitride substrates have been grown using aqueous zinc salts such as zinc nitrate and zinc acetate in basic environments. Pre-seeding substrates with Zinc oxide creates sites for homogeneous nucleation of Zinc oxide crystal during the synthesis. Common pre-seeding methods include in-situ thermal decomposition of zinc acetate crystallites, spincoating of Zinc oxide nanoparticles and the use of physical vapor deposition methods to deposit Zinc oxide thin films. Pre-seeding can be performed in conjunction with top down patterning methods such as electron beam lithography and nanosphere lithography to designate nucleation sites prior to growth. Aligned Zinc oxide nanowires can be used in dye-sensitized solar cells and field emission devices. History of Zinc oxide Zinc compounds were probably used by early humans, in processed and unprocessed forms, as a paint or medicinal ointment, but their composition is uncertain. The use of pushpanjan, probably zinc oxide, as a salve for eyes and open wounds, is mentioned in the Indian medical text the Charaka Samhita, thought to date from 500 BC or before. Zinc oxide ointment is also mentioned by the Greek physician Dioscorides (1st century AD). Galen suggested treating ulcerating cancers with zinc oxide, as did Avicenna in his The Canon of Medicine. Zinc oxide is no longer used for treating skin cancer, though it is still used as an ingredient in products such as baby powder and creams against diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. The Romans produced considerable quantities of brass (an alloy of zinc and copper) as early as 200 BC by a cementation process where copper was reacted with zinc oxide. The zinc oxide is thought to have been produced by heating zinc ore in a shaft furnace. This liberated metallic zinc as a vapor, which then ascended the flue and condensed as the oxide. This process was described by Dioscorides in the 1st century AD. Zinc oxide has also been recovered from zinc mines at Zawar in India, dating from the second half of the first millennium BC. From the 12th to the 16th century zinc and zinc oxide were recognized and produced in India using a primitive form of the direct synthesis process. From India, zinc manufacture moved to China in the 17th century. In 1743, the first European zinc smelter was established in Bristol, United Kingdom. Around 1782 Louis-Bernard Guyton de Morveau proposed replacing lead white with zinc oxide. The main usage of zinc oxide (zinc white) was in paints and as an additive to ointments. Zinc white was accepted as a pigment in oil paintings by 1834 but it did not mix well with oil. This problem was solved by optimizing the synthesis of Zinc oxide. In 1845, LeClaire in Paris was producing the oil paint on a large scale, and by 1850, zinc white was being manufactured throughout Europe. The success of zinc white paint was due to its advantages over the traditional white lead: zinc white is essentially permanent in sunlight, it is not blackened by sulfur-bearing air, it is non-toxic and more economical. Because zinc white is so "clean" it is valuable for making tints with other colors, but it makes a rather brittle dry film when unmixed with other colors. For example, during the late 1890s and early 1900s, some artists used zinc white as a ground for their oil paintings. All those paintings developed cracks over the years. In recent times, most zinc oxide was used in the rubber industry to resist corrosion. In the 1970s, the second largest application of Zinc oxide was photocopying. High-quality Zinc oxide produced by the "French process" was added to photocopying paper as a filler. This application was soon displaced by titanium. Applications of Zinc oxide The applications of zinc oxide powder are numerous, and the principal ones are summarized below. Most applications exploit the reactivity of the oxide as a precursor to other zinc compounds. For material science applications, zinc oxide has high refractive index, high thermal conductivity, binding, antibacterial and UV-protection properties. Consequently, it is added into materials and products including plastics, ceramics, glass, cement, rubber, lubricants, paints, ointments, adhesive, sealants, concrete manufacturing, pigments, foods, batteries, ferrites, fire retardants, etc. Rubber manufacture of Zinc oxide Between 50% and 60% of Zinc oxide use is in the rubber industry. Zinc oxide along with stearic acid is used in the vulcanization of rubber Zinc oxide additive also protect rubber from fungi (see medical applications) and UV light. Ceramic industry Ceramic industry consumes a significant amount of zinc oxide, in particular in ceramic glaze and frit compositions. The relatively high heat capacity, thermal conductivity and high temperature stability of Zinc oxide coupled with a comparatively low coefficient of expansion are desirable properties in the production of ceramics. Zinc oxide affects the melting point and optical properties of the glazes, enamels, and ceramic formulations. Zinc oxide as a low expansion, secondary flux improves the elasticity of glazes by reducing the change in viscosity as a function of temperature and helps prevent crazing and shivering. By substituting Zinc oxide for BaO and PbO, the heat capacity is decreased and the thermal conductivity is increased. Zinc in small amounts improves the development of glossy and brilliant surfaces. However, in moderate to high amounts, it produces matte and crystalline surfaces. With regard to color, zinc has a complicated influence. Medicine Zinc oxide as a mixture with about 0.5% iron(III) oxide (Fe2O3) is called calamine and is used in calamine lotion. Two minerals, zincite and hemimorphite, have been historically called calamine. When mixed with eugenol, a ligand, zinc oxide eugenol is formed, which has applications as a restorative and prosthodontic in dentistry. Reflecting the basic properties of Zinc oxide, fine particles of the oxide have deodorizing and antibacterial properties and for that reason are added into materials including cotton fabric, rubber, oral care products, and food packaging. Enhanced antibacterial action of fine particles compared to bulk material is not exclusive to Zinc oxide and is observed for other materials, such as silver. This property results from the increased surface area of the fine particles. Zinc oxide is used in mouthwash products and toothpastes as an anti-bacterial agent proposed to prevent plaque and tartar formation, and to control bad breath by reducing the volatile gases and volatile sulphur compounds (VSC) in the mouth. Along with zinc oxide or zinc salts, these products also commonly contain other active ingredients, such as cetylpyridinium chloride, xylitol, hinokitiol, essential oils and plant extracts. Zinc oxide is widely used to treat a variety of skin conditions, including atopic dermatitis, contact dermatitis, itching due to eczema, diaper rash and acne. Zinc oxide is also often added into sunscreens. It is used in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. It is also a component in tape (called "zinc oxide tape") used by athletes as a bandage to prevent soft tissue damage during workouts. Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light (see sunscreen). It is the broadest spectrum UVA and UVB absorber that is approved for use as a sunscreen by the U.S. Food and Drug Administration (FDA), and is completely photostable. When used as an ingredient in sunscreen, zinc oxide blocks both UVA (320–400 nm) and UVB (280–320 nm) rays of ultraviolet light. Zinc oxide and the other most common physical sunscreen, titanium dioxide, are considered to be nonirritating, nonallergenic, and non-comedogenic. Zinc from zinc oxide is, however, slightly absorbed into the skin. Many sunscreens use nanoparticles of zinc oxide (along with nanoparticles of titanium dioxide) because such small particles do not scatter light and therefore do not appear white. The nanoparticles are not absorbed into the skin more than regular-sized zinc oxide particles are, and are only absorbed into the outermost layer of the skin but not into the body. Zinc oxide nanoparticles can enhance the antibacterial activity of ciprofloxacin. It has been shown that nano Zinc oxide that has an average size between 20 nm and 45 nm can enhance the antibacterial activity of ciprofloxacin against Staphylococcus aureus and Escherichia coli in vitro. The enhancing effect of this nanomaterial is concentration dependent against all test strains. This effect may be due to two reasons. First, zinc oxide nanoparticles can interfere with NorA protein, which is developed for conferring resistance in bacteria and has pumping activity that mediate the effluxing of hydrophilic fluoroquinolones from a cell. Second, zinc oxide nanoparticles can interfere with Omf protein, which is responsible for the permeation of quinolone antibiotics into the cell. Cigarette filters Zinc oxide is a component of cigarette filters. A filter consisting of charcoal impregnated with zinc oxide and iron oxide removes significant amounts of hydrogen cyanide (HCN) and hydrogen sulfide (H2S) from tobacco smoke without affecting its flavor. Food additive Zinc oxide is added to many food products, including breakfast cereals, as a source of zinc, a necessary nutrient. (Zinc sulfate is also used for the same purpose.) Some prepackaged foods also include trace amounts of Zinc oxide even if it is not intended as a nutrient. Zinc oxide was linked to dioxin contamination in pork exports in the 2008 Chilean pork crisis. The contamination was found to be due to dioxin contaminated zinc oxide used in pig feed. Pigment Zinc white is used as a pigment in paints and is more opaque than lithopone, but less opaque than titanium dioxide. It is also used in coatings for paper. Chinese white is a special grade of zinc white used in artists' pigments. The use of zinc white (zinc oxide) as a pigment in oil painting started in the middle of 18th century. It has partly replaced the poisonous lead white and was used by painters such as Böcklin, Van Gogh, Manet, Munch and others. It is also a main ingredient of mineral makeup (CI 77947). UV absorber Micronized and nano-scale zinc oxide and titanium dioxide provide strong protection against UVA and UVB ultraviolet radiation, and are used in suntan lotion, and also in UV-blocking sunglasses for use in space and for protection when welding, following research by scientists at Jet Propulsion Laboratory (JPL). Coatings Paints containing zinc oxide powder have long been utilized as anticorrosive coatings for metals. They are especially effective for galvanized iron. Iron is difficult to protect because its reactivity with organic coatings leads to brittleness and lack of adhesion. Zinc oxide paints retain their flexibility and adherence on such surfaces for many years. Zinc oxide highly n-type doped with aluminium, gallium, or indium is transparent and conductive (transparency ~90%, lowest resistivity ~10−4 Ω·cm). Zinc oxide:Al coatings are used for energy-saving or heat-protecting windows. The coating lets the visible part of the spectrum in but either reflects the infrared (IR) radiation back into the room (energy saving) or does not let the IR radiation into the room (heat protection), depending on which side of the window has the coating. Plastics, such as polyethylene naphthalate (PEN), can be protected by applying zinc oxide coating. The coating reduces the diffusion of oxygen with PEN. Zinc oxide layers can also be used on polycarbonate in outdoor applications. The coating protects polycarbonate from solar radiation, and decreases its oxidation rate and photo-yellowing. Corrosion prevention in nuclear reactors Zinc oxide depleted in 64Zn (the zinc isotope with atomic mass 64) is used in corrosion prevention in nuclear pressurized water reactors. The depletion is necessary, because 64Zn is transformed into radioactive 65Zn under irradiation by the reactor neutrons. Methane reforming Zinc oxide (ZnO) is used as a pretreatment step to remove hydrogen sulfide (H2S) from natural gas following hydrogenation of any sulfur compounds prior to a methane reformer, which can poison the catalyst. At temperatures between about 230–430 °C (446–806 °F), H2S is converted to water by the following reaction: H2S + Zinc oxide → H2O + ZnS The zinc sulfide (ZnS) is replaced with fresh zinc oxide when the zinc oxide has been consumed. Potential applications of Zinc oxide Electronics Zinc oxide has wide direct band gap (3.37 eV or 375 nm at room temperature). Therefore, its most common potential applications are in laser diodes and light emitting diodes (LEDs). Some optoelectronic applications of Zinc oxide overlap with that of GaN, which has a similar band gap (~3.4 eV at room temperature). Compared to GaN, Zinc oxide has a larger exciton binding energy (~60 meV, 2.4 times of the room-temperature thermal energy), which results in bright room-temperature emission from Zinc oxide. Zinc oxide can be combined with GaN for LED-applications. For instance as transparent conducting oxide layer and Zinc oxide nanostructures provide better light outcoupling. Other properties of Zinc oxide favorable for electronic applications include its stability to high-energy radiation and its possibility to be patterned by wet chemical etching. Radiation resistance makes Zinc oxide a suitable candidate for space applications. Zinc oxide is the most promising candidate in the field of random lasers to produce an electronically pumped UV laser source. The pointed tips of Zinc oxide nanorods result in a strong enhancement of an electric field. Therefore, they can be used as field emitters. Aluminium-doped Zinc oxide layers are used as transparent electrodes. The components Zn and Al are much cheaper and less toxic compared to the generally used indium tin oxide (ITO). One application which has begun to be commercially available is the use of Zinc oxide as the front contact for solar cells or of liquid crystal displays. Transparent thin-film transistors (TTFT) can be produced with Zinc oxide. As field-effect transistors, they even may not need a p–n junction, thus avoiding the p-type doping problem of Zinc oxide. Some of the field-effect transistors even use Zinc oxide nanorods as conducting channels. Zinc oxide nanorod sensor Zinc oxide nanorod sensors are devices detecting changes in electric current passing through zinc oxide nanowires due to adsorption of gas molecules. Selectivity to hydrogen gas was achieved by sputtering Pd clusters on the nanorod surface. The addition of Pd appears to be effective in the catalytic dissociation of hydrogen molecules into atomic hydrogen, increasing the sensitivity of the sensor device. The sensor detects hydrogen concentrations down to 10 parts per million at room temperature, whereas there is no response to oxygen. Zinc oxide have been used as immobilization layers in imunosensors enabling the distribution of antibodies across the entire region probed by the measuring electric field applied to the microelectrodes. Spintronics Zinc oxide has also been considered for spintronics applications: if doped with 1–10% of magnetic ions (Mn, Fe, Co, V, etc.), Zinc oxide could become ferromagnetic, even at room temperature. Such room temperature ferromagnetism in Zinc oxide:Mn has been observed, but it is not clear yet whether it originates from the matrix itself or from secondary oxide phases. Piezoelectricity The piezoelectricity in textile fibers coated in Zinc oxide have been shown capable of fabricating "self-powered nanosystems" with everyday mechanical stress from wind or body movements. In 2008 the Center for Nanostructure Characterization at the Georgia Institute of Technology reported producing an electricity generating device (called flexible charge pump generator) delivering alternating current by stretching and releasing zinc oxide nanowires. This mini-generator creates an oscillating voltage up to 45 millivolts, converting close to seven percent of the applied mechanical energy into electricity. Researchers used wires with lengths of 0.2–0.3 mm and diameters of three to five micrometers, but the device could be scaled down to smaller size. Zinc oxide as anode of Li-ion battery In form of a thin film Zinc oxide has been demonstrated in miniaturised high frequency thin film resonators, sensors and filters. Li-ion battery Zinc oxide is a promising anode material for lithium-ion battery because it is cheap, biocompatible, and environmentally friendly. Zinc oxide has a higher theoretical capacity (978 mAh g−1) than many other transition metal oxides such as CoO (715 mAh g−1), NiO (718 mAh g−1) and CuO (674 mAh g−1). Safety of Zinc oxide As a food additive, zinc oxide is on the U.S. FDA's list of generally recognized as safe, or GRAS, substances. Zinc oxide itself is non-toxic; it is hazardous, however, to inhale zinc oxide fumes, such as generated when zinc or zinc alloys are melted and oxidized at high temperature. This problem occurs while melting alloys containing brass because the melting point of brass is close to the boiling point of zinc.Exposure to zinc oxide in the air, which also occurs while welding galvanized (zinc plated) steel, can result in a malady called metal fume fever. For this reason, typically galvanized steel is not welded, or the zinc is removed first. Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically. It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. Zinc oxide is mildly astringent and is used topically as a soothing and protective application in eczema and slight excoriations, in wounds, and for hemorrhoids. It is also used with coal tar or ichthammol in the treatment eczema. Zinc oxide is used as the basis for the production of a number of dental cements. Mixed with phosphoric acid it forms a hard material composed largely of zinc phosphate; mixed with clove oil or eugenol, it is used as temporary dental filling. Pharmacologic levels of zinc as zinc oxide have consistently been found to increase pig performance during the postweaning period. In some instances, high levels of zinc oxide have been reported to reduce the incidence and severity of postweaning diarrhea. Responses to zinc oxide and antibiotics seem to be additive in nature, much like the responses to high copper and antibiotics; however, there is no advantage in including high copper and high zinc in the same diet. Zinc oxide accounts for the largest use of zinc compounds, and is used primarily by the rubber industry as a vulcanization activator and accelerator and to slow rubber aging by neutralizing sulfur and organic acids formed by oxidation. It also acts in rubber as a reinforcing agent, a heat conductor, a white pigment, and an absorber of UV light. In paints, zinc oxide serves as a mildewstat, acid buffer, and a pigment. It is used in animal feed as a zinc supplement and as a fertilizer additive for zinc-deficient soils. Zinc oxide is used in cosmetics and drugs primarily for its fungicide properties, and in dentistry in dental cements. It is also used in ceramics, in glass manufacture, as a catalyst in organic synthesis, and in coated photocopy paper. Two processes are used to produce metallic zinc from the ore concentrates that are not subjected to caustic soda leaching. In one process, the ore concentrate containing zinc sulfide is roasted in the presence of air to produce zinc oxide, which is combined with coke or coal and retorted to approximately 1,100 °C to produce metallic zinc. In the other process, the roasted zinc oxide is leached with sulfuric acid, and the solution is electrolyzed to produce zinc of >99.9% purity. Zinc oxide is also produced industrially from purified solutions of zinc sulfate or chloride by precipitating the basic carbonate, which is then washed, filtered, and finally calcined. This method produces a grade of zinc oxide with a high specific surface area. Products of this type are also obtained from waste hydroxides which are purified by a chemical route and then calcined. Residues of zinc oxide are exempted from the requirement of a tolerance when used as a coating agent in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.
ZINC PEROXIDE
Zinc orthophosphate; Phosphoric acid, zinc salt (2:3); Zinc Phosphate; Trizinc bis(orthophosphate); Trizinkbis(orthophosphat) (German); Bis(ortofosfato) de tricinc (Spanish); Bis(orthophosphate) de trizinc (French); cas no: 7779-90-0
ZINC PHOSPHATE
CAS Number: 7779-90-0
PubChem CID: 24519
Molecular Weight: 386.1
Linear Formula: Zn3(PO4)2



APPLICATIONS


Zinc phosphate dental cement is one of the oldest and widely used dental cements.
However, Zinc Phosphate is commonly used for luting permanent metal and zirconium dioxide[4][5][6][7][8][9] restorations and as a base for dental restorations.
Zinc phosphate cement is used for cementation of inlays, crowns, bridges, and orthodontic appliances and occasionally as a temporary restoration.

Zinc Phosphate is prepared by mixing zinc oxide and magnesium oxide powders with a liquid consisting principally of phosphoric acid, water, and buffers.
Further, Zinc Phosphate is the standard cement to measure against.

Zinc Phosphate has the longest track record of use in dentistry.
More to that, Zinc Phosphate is still commonly used; however, resin-modified glass ionomer cements are more convenient and stronger when used in a dental setting.

Zinc Phosphate is used for coatings.
We can divide zinc phosphate coatings into three sections according to application areas:

Application for preventing abrasion caused by friction before metal forming processes such as cold drawing, cold forging, deep drawing,
Application for increasing paint adhesion before electrostatic powder coating and wet painting,
Application for increasing wear resistance and corrosion resistance with protective lubrication.

When Zinc Phosphate is used before forming of metals, coating weight of 5 - 15 g/m2 is usually required.
Zinc Phosphate is most commonly used in wire and tube drawing processes.
The Zinc Phosphate layer is firmly attached to the metal surface and reduces friction in the dies and molds during the cold drawing process, allowing these operations to be carried out easily.

Zinc Phosphate layer remaining on the surface after the drawing operation creates high corrosion resistance during storage and transportation and prevents rusting.
Further, Zinc Phosphate coating is of great importance in high carbon wire drawing industry such as steel rope, spring, welding wire, pc wire, pc strand production.

Zinc Phosphate provides continuity on the surface for multiple drawing operations and enables high drawing speeds.
Moreover, Zinc Phosphate enables difficult cold forging operations in the production of bolts and screws and ensures long service life of molds.

If zinc phosphate coating will be applied under paint, a coating in the range of 2-6 g/m2 must be obtained on the metal part.
Making a uniform coating with thin crystal structure is important in terms of adhesion to paint and to provide corrosion resistance in harsh environmental conditions.

The desired coating weight for protective oil application is in the range of 10-35 g/m2.
Zinc phosphate coating with coarse crystal structure and high coating weight retains the protective oil and provides an effective corrosion resistance.

Zinc Phosphate is widely used for auto parts, fasteners and machine parts.

Zinc phosphate is used to produce corrosion resistant coatings that are typically applied either as part of an electroplating process or as a primer pigment.
Furthermore, Zinc Phosphate reacts moderately with water and is acid soluble with zinc sources, allowing it to have good moisture resistance and galvanic substitution properties.
When used in a micronized form for pigmentation Zinc Phosphate is suitable for a wide range of primer applications.

Zinc phosphate is also a key component of zinc orthophosphate hydrate, which is a protective compound that is easy to disperse.
The low solubility behavior of Zinc Phosphate provides high compatibility with both solvent- and water-based resins.

Zinc Phosphate is used in dental cements, phosphors, and coatings of steel and aluminum
Zinc Phosphate is the most important phosphate-containing pigment--reacts with iron to produce a protective film.

Some uses of Zinc Phosphate:
Corrosion inhibitor
Dyes
Filler
Paint additives and coating additives not described by other categories
Pigment
Stabilizing agent
Surface modifier
Adhesion/cohesion promoter
Agricultural chemicals (non-pesticidal)
Plating agents and surface treating agents

Zinc Phosphate is used in the manufacturing of dyes.
Further, Zinc Phosphate is used as a plating agent as well as a surface treating agent.
Zinc Phosphate is used as a corrosion inhibitor.

Zinc Phosphate is used as an additive in paints.
Moreover, Zinc Phosphate is used in water treatment products.

Zinc Phosphate is an anti-scaling agent.
More to that, Zinc Phosphate is used in preparing rubber products.


Other uses of Zinc Phosphate:

Materials used for construction (e.g. flooring, tile, sinks, bathtubs, mirrors, wall materials/drywall, wall-to-wall carpets)
Corrosion inhibitor
Furniture and furnishings
Items used to furnish a home or workplace, e.g. tables, chairs, sofa, outdoor patio furniture, sofa cover, hammock, mattress, area rug
Adhesives and adhesive removers
Extender pigment
Filler
Filler
Multipurpose adhesive
General purpose repair adhesives including all purpose glues, super glue, and epoxies; not including wood glues
Paint/stain and related products
Home improvement paints, excluding or not specified as oil-, solvent-, or water-based paints
Paints applied to hard surfaces that are intended to be painted over and that improve adhesion, coverage, or prevent the bleeding through of stains
Products used on wooden surfaces, including decks, to impart transparent or semitransparent color
Dental care
Toothpastes and dentrifices
Inhibitor

Zinc phosphate coating is a crystallized conversion coating formed on the metal surface.
The Zinc Phosphate coating process is based on the chemical reaction between the metal and the weak acidic phosphate fluid to form insoluble phosphate crystals on the surface of the part.

Zinc Phosphate coating is used as a pretreatment before painting, to increase corrosion resistance and to provide a better adhesion surface for coating systems.
When used alone or with oil, Zinc Phosphate reduces the friction characteristics of the moving components or threaded parts.

Although Zinc Phosphate is generally referred to as a coating, since phosphate alone has a low rust resistance, it must be used in combination with oil or top lacquer applications in order to be used as a protection against corrosion.
Zinc phosphate can be applied to Ferrous metals, but it has no effect on Stainless Steel.

Advantages of Zinc Phosphate:

Zinc Phosphate provides corrosion resistance.
Further, Zinc Phosphate provides a good adhesion surface for Paint and Organic coatings.
Zinc Phosphate helps for the reduction of friction coefficient when applied with oil.

Zinc phosphate enhances paint adhesion by giving the paint something to bond to securely.
Moreover, Zinc Phosphate reduces paint-to-metal reactions and forms a barrier between the substrate and the paint.
Zinc phosphate also reduces general surface corrosion on metal substrates and reduces underfilm delamination in the event of damage to the paint film.

There are three types of Zinc Phosphate coatings.
Iron phosphate is a lightweight amorphous coating.
It generally has a coating weight between 15-100 mg/ft2 and typically used as paint base for low-corrosion environments.

A modified zinc phosphate coating is a medium weight crystalline phosphate coating.
It has a coating weight between 150-350 mg/ft2.
It is typically used as paint base for high-corrosion environments.

A heavy zinc phosphate coating produces a very heavy coating weight, typically between 700-3,500 mg/ft2.
It is used for unpainted applications.
When applying a zinc phosphate coating to metal, remember that high temperatures cause excessive phosphate sludge, resulting in high chemical and maintenance costs.
An efficient zinc phosphate coating can have several long-term benefits, including fewer rejects, higher throughput, decreased downtime, and lower maintenance costs.

Zinc phosphate is widely used in automotive and military applications, but is used to a lesser extent in general industry where high paint performance may not be required.
Since neither iron phosphate nor green technologies can out-perform zinc phosphate, zinc phosphate will be in use for many years to come.

The big change will come in the future when new technologies perform as well as zinc phosphate combined with an economic incentive of cost reduction.
At that point, we will see a major shift to green technologies.



DESCRIPTION


Zinc phosphate is an inorganic compound with the formula Zn3(PO4)2.
This white powder is widely used as a corrosion resistant coating on metal surfaces either as part of an electroplating process or applied as a primer pigment (see also red lead).

Zinc Phosphate has largely displaced toxic materials based on lead or chromium, and by 2006 it had become the most commonly used corrosion inhibitor.
Furthermore, Zinc phosphate coats better on a crystalline structure than bare metal, so a seeding agent is often used as a pre-treatment.
One common agent is sodium pyrophosphate.

Zinc Phosphate appears in the form of white crystals.
The molecular weight of Zinc Phosphate is 386.11 g/mol.

The density of Zinc Phosphate is 3.998 g/cm3.
The melting point of Zinc Phosphate is 900°C.
Zinc Phosphate is a nonflammable compound.

Zinc Phosphate is an inorganic compound that combines phosphorus with zinc.

Zinc Phosphate is used in rodenticide baits.
When an animal eats the bait, the acid in the animal's stomach turns the zinc phosphide into phosphine.
Zinc Phosphate causes a very toxic gas.

Zinc Phosphate is also released by aluminum phosphide and magnesium phosphide.
These are used as fumigants in stored grain.

Zinc Phosphate has been registered for use in pesticide products in the United States since 1947.

Natural forms of Zinc Phosphate include minerals hopeite and parahopeite.
A somewhat similar mineral is natural hydrous zinc phosphate called tarbuttite, Zn2(PO4)(OH).
Both are known from oxidation zones of Zn ore beds and were formed through oxidation of sphalerite by the presence of phosphate-rich solutions.
The anhydrous form of Zinc Phosphate has not yet been found naturally.

Zinc phosphate is an inorganic chemical compound consisting of zinc, phosphorous and oxygen with the chemical formula Zn3(PO4)2.
Furthermore, Zinc Phosphate is commonly used as a corrosion inhibitor when applied to metallic surfaces.

Zinc Phosphate is a material used for cementation of inlays, crowns, bridges, and orthodontic appliances and occasionally as a temporary restoration.
Moreover, Zinc Phosphate is prepared by mixing zinc oxide and magnesium oxide powders with a liquid consisting principally of phosphoric acid, water, and buffers.

Zinc Phosphate is an inorganic chemical compound having a chemical name Zinc Phosphate.
The other names for Zinc Phosphate are Zinc orthophosphate, Trizinc phosphate, and Trizinc diphosphate.
This white powder compound is widely used as a corrosion-resistant coating, which is applied on the metal surfaces, which are put as a part of electroplating or as a primer pigment.

Zinc Phosphate is a universal lead-free and chromium-free inorganic corrosion inhibitor designed for water-based and solvent-based coatings.
Further, Zinc Phosphate exhibits a high degree of versatility because of its narrow particle size distribution: upper particle size limit of 20 microns, mean particle size of 5 microns.

Zinc Phosphate is an important antioxidant nutrient and functions as a cofactor for numerous enzymes, including those involved in DNA and RNA replication, protein synthesis, insulin production and brain development.
Despite the importance of this mineral, our bodies cannot store excess Zinc as it naturally does with some other minerals and vitamins, so continuous dietary intake is required.

When compared to the bare metal, the trizinc phosphate coats better on a crystalline structure.
Thus, a seeding agent like sodium pyrophosphate is used frequently as a pre-treatment.
Zinc Phosphate has largely displaced toxic materials based on chromium or lead.

Zinc Phosphate had become one of the most commonly used corrosion inhibitors by 2006.
The common agent of this Zinc Phosphate is sodium pyrophosphate.

Zinc Phosphate is a moderately water and acid soluble Zinc source for uses compatible with Phosphates.

Zinc Phosphate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.



PROPERTIES


Chemical formula: H4O12P2Zn3
Molar mass: 454.11 g·mol−1
Appearance: white solid
Density: 3.998 g/cm3
Melting point: 900 °C (1,650 °F; 1,170 K)
Boiling point: 158 °C (316 °F; 431 K)
Solubility in water: insoluble
Magnetic susceptibility (χ): −141.0·10−6 cm3/mol

Refractive index (nD): 1.595
Molecular Weight: 386.1
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 8
Rotatable Bond Count: 0
Exact Mass: 383.69116
Monoisotopic Mass: 381.69427
Topological Polar Surface Area: 173 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 36.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes



SYNONYMS


Zinc Phosphate
7779-90-0
Trizinc phosphate
Phosphoric acid, zinc salt
Trizinc diphosphate
Zinc orthophosphate
trizinc;diphosphate
Trizinc bis(orthophosphate)
Tribasic zinc phosphate
Phosphoric acid, zinc salt (2:3)
Zincphosphate
704TVM
13847-22-8
14485-28-0
1E2MCT2M62
Delaphos
Delaphos 2M
Bonderite 40
Granodine 80
Microphos 90
Granodine 16NC
Zinc acid phosphate
Bonderite 181
Bonderite 880
Heucophos ZP 10
Pigment White 32
Sicor ZNP/M
Sicor ZNP/S
Phosphinox PZ 06
Virchem 931
Fleck's Extraordinary
LF Bowsei PW 2
Neutral zinc phosphate
Weather coat 1000
ZP-DL
ZP-SB
Zinc phosphate (3:2)
Man-Gill 51339
Man-Gill 51355
C.I. Pigment White 32
ZINC PHOSPHATE CEMENT
Fleck's Extraordinary Cement
LF-PW 2
Zinc ortho-phosphate
EINECS 231-944-3
UNII-1E2MCT2M62
C.I. 77964
J 0852
EINECS 237-583-8
zinc(II) phosphate
Zinc phosphate-tribasic
EC 231-944-3
ZINC PHOSPHATE [MI]
ZINC PHOSPHATE [INCI]
ZINC PHOSPHATE [VANDF]
CHEMBL2286756
DTXSID3064807
ZINC PHOSPHATE [WHO-DD]
Zinc phosphate, analytical standard
EINECS 238-280-3
Phosphoric acid, zinc salt (1:?)
MFCD00036282
AKOS024418785
FT-0696571
Zinc phosphate, 99.998% trace metals basis
Q59714
Zinc phosphate (ortho), 99.995% (metals basis)
2,2-(1,2-Ethenediyldi-4,1-phenylene)bisbenzoxazole















ZINC PHOSPHATE
Zinc; Zn; Zinc dust; cinc cas no: 7440-66-6
ZINC POWDER
Zinc bis-(2-Pyridinethiol-1-oxide); ZNPT; ZPT; Zinc, bis(2-pyridylthio)-, N,N'-dioxide; 1-Hydroxy-2-pyridinethione, zinc salt; 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex; 2-Mercaptopyridine 1-oxide Zinc Salt; 2-Pyridinethiol N-oxide zinc salt; 2-Pyridinethiol, 1-oxide, zinc salt; Zinc, Bis(2-pyridinylthio)-, N,N'-dioxide; Zinc, Bis(2-pyridylthio)-, 1,1'-dioxide; Zinc, Bis(2-pyridylthio)-, N,N'-dioxide; Zincpolyanemine; Zinksalz Des 1-hydroxi-2-pyridinthion CAS NO:13463-41-7
ZINC PYRITHIONE
Zinc pyrithione is a preservative that is also used in anti-dandruff shampoos for anti-fungal functions.
Zinc pyrithione works to treat dandruff at the root cause by functioning as a fungicide with specific efficacy against Malassezia.
Zinc pyrithione has anti-fungal properties and appears as a crystalline powder in raw form that is white or slightly yellow in color.

CAS Number: 68890-66-4
EC Number: 272-574-2
Molecular Formula: C14H23NO2·C2H7NO
Molecular Weight: 298.42

PIROCTONE OLAMINE, 68890-66-4, Octopirox, Piroctone ethanolamine, Kopirox, Piroctoneolamine, Octopyrox, Piroctone ethanolamine salt, Piroctone olamine [USAN], C14H23NO2.C2H7NO, 2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, EINECS 272-574-2, UNII-A4V5C6R9FB, A4V5C6R9FB, NSC-759894, PIROCTONE ETHANOLAMINE SALT (1:1), Piroctone olamine (USAN), EC 272-574-2, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one 2-aminoethanol salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethan-1-ol (1:1), Octopirox (TN), SCHEMBL2843, CHEMBL2107154, PIROCTONE OLAMINE [INCI], PIROCTONE OLAMINE [MART.], PIROCTONE OLAMINE [USP-RS], AMY40819, BCP29912, HY-B1345, MFCD01690792, s5213, Piroctone olamine, analytical standard, AKOS025149526, CCG-267454, CS-7659, NSC 759894, PIROCTONE ETHANOLAMINE [WHO-DD], AS-15254, C14-H23-N-O2.C2-H7-N-O, LS-133057, FT-0653357, P2178, D05505, Piroctone ethanolamine salt; Octopirox; Kopirox, PIROCTONE ETHANOLAMINE SALT (1:1) [MI], A836281, Q412572, W-104652, 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone Ethanolamine, Piroctone olamine, United States Pharmacopeia (USP) Reference Standard, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-1,2-dihydropyridin-2-one; 2-aminoethan-1-ol, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2 pyridon and its monoethanolamine salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt, 1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)-2-PYRIDONE MONOETHANOLAMINE, (+/-)-, 1- hydroxy- 4- methyl- 6- (2, 4, 4- trimethylpentyl)pyridin- 2(1H)- one, compound with 2- aminoethanol (1:1), Ethanol, 2-amino-, compd. with 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone (1:1) (9CI); 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt; Octopirox; Octopyrox; Piroctone ethanolamine salt; Piroctone olamine, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinon --2-aminoethanol (1:1) [German] [ACD/IUPAC Name], 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinon--2-aminoethanol(1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone - 2-aminoethanol (1:1) [ACD/IUPAC Name], 1-Hydroxy-4-méthyl-6-(2,4,4-triméthylpentyl)-2(1H)-pyridinone - 2-aminoéthanol (1:1) [French] [ACD/IUPAC Name], 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone 2-Aminoethanol Salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one - 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compd. with 2-aminoethanol (1:1) [ACD/Index Name], 272-574-2 [EINECS], 68890-66-4 [RN], A4V5C6R9FB, MFCD01690792, octopirox [Trade name], Piroctone ethanolamine, Piroctone ethanolamine salt, Piroctone olamine [Wiki], UNII:A4V5C6R9FB, [68890-66-4] [RN], 1-Aminoethane, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanol ammonium salt, 1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethan-1-ol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compound with 2-aminoethanol (1:1), 2-aminoethanol and 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, 2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, 2-hydroxyethylammonium; 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone, Octopirox| Piroctone ethanolamine, Piroctone, Piroctone olamin, PIROCTONE OLEAMINE, QA-6124

Zinc pyrithione is a compound sometimes used in the treatment of fungal infections.
Zinc pyrithione is the ethanolamine salt of the hydroxamic acid derivative piroctone.

Zinc pyrithione is often used in anti-dandruff shampoo as a replacement for the commonly used compound zinc pyrithione.
Zinc pyrithione is structurally similar to ciclopirox and pyrithione, containing a substituted pyridine (pyridinone) group which inhibits ergosterol synthesis.

Zinc pyrithione is a preservative that is also used in anti-dandruff shampoos for Zinc pyrithione anti-fungal functions.

Zinc pyrithione, also known as Piroctone olamine, was developed as a solution to the problem of seborrheic dermatitis, that is, dandruff, and has antibacterial, antimicrobial and antifungal properties that can help treat scalp psoriasis and acne.
The mentioned properties can destroy fungi, bacteria and microorganisms that can cause itchy complaints in the hair and scalp and cause the scalp to become flaky.

Zinc pyrithione has the potential to have antifungal effects to prevent or treat fungal infections.
Zinc pyrithione helps reduce inflammation in the skin.

Zinc pyrithione provides antioxidant effect by protecting the skin from the harmful effects of free radicals.
Zinc pyrithione shows cleansing potential to remove dirt, oil and debris.
Zinc pyrithione can help eliminate bad odors.

Zinc pyrithione is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
Zinc pyrithione works to treat dandruff at the root cause by functioning as a fungicide with specific efficacy against Malassezia.

Zinc pyrithione is a synthetic ingredient that is used mainly as a preservative in personal care and cosmetic products.
Shampoos with Zinc pyrithione are very effective in curing dandruff and preventing hair loss.

Zinc pyrithione (or Piroctone olamine) is a coordination complex of zinc.
Zinc pyrithione has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis[2] and dandruff.

Zinc pyrithione has anti-fungal properties and appears as a crystalline powder in Zinc pyrithione raw form that is white or slightly yellow in color.
Further, Zinc pyrithione is slightly soluble in oil and water.
The chemical formula of Zinc pyrithione is C14H23NO2.C2H7NO.

Zinc pyrithione has a petrochemical origin.
Zinc pyrithione is an ethanolamine salt extracted from hydroxamic acid derivative piroctone.
Typically, Zinc pyrithione is an alternative to the commonly used compound zinc pyrithione.

Almost everyone faces hair related issues like dandruff, hair loss, slow hair growth, and split ends.
Shampoos containing Zinc pyrithione are effective in treating various kinds of hair problems.

Zinc pyrithione is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and at the same time, provided hair conditioning advantages.
Recently was shown, that Zinc pyrithione could induce apoptosis and possessed a significant in vivo effect against myeloma.

Zinc pyrithione is a pyridone derivative, which is known to have bactericidal effects on gram-positive and gram-negative bacteria and fungicidal effects and hence is a component of many cosmetic products such as anti-dandruff shampoo.

Zinc pyrithione, also called Octopirox, is an antifungal of the hydroxy-pyridone family unrelated to other antiseptics used in veterinary medicine.
Members of the “pirox” family are currently used in the human field as topicals to cure onychomycosis and Malassezia-related skin disorders.

Zinc pyrithione has broad in vitro activity against major dermal veterinary pathogens, including dermatophytes and yeasts as well as some Gram positive (Staphylococcus) and Gram negative (Pseudomonas) bacteria.
As opposed to azole derivatives, PO remains fully active on resting fungal cells; Zinc pyrithione antiseptic activity proceeds from inhibition of the respiratory chain in yeast mitochondria.

No resistance to PO has been documented to date.
In addition, this antiseptic acts at low concentrations, has high affinity for keratin and is completely safe.
Incorporation of PO in Allermyl therefore aims at controlling microbial proliferation associated with allergic disease.

Zinc pyrithione is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Zinc pyrithione is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Zinc pyrithione is known for many years as a successor to Ketoconazole as an excellent anti-dandruff agent.
More recently Zinc pyrithione has been discovered that Zinc pyrithione has a much broader protection range against all kinds of microbiological species.

Is also being used in many preservative formulations at neutral pH, which is important for sunscreen formulations.

Zinc pyrithione is slightly soluble in both water and oil.
Freely soluble in 10% ethanol in water.

Soluble in solutions containing surfactants in water or in 1-10% ethanol.
The solubility of Zinc pyrithione in water varies by pH value.
This is a little larger in neutral or weak basic solutions than in acid solutions.

Typical use level is only 0.05 – 0.2%.

Zinc pyrithione is a hydroxamic acid that inhibits ergosterol synthesis, the main component of the cell wall of most fungi.
Zinc pyrithione is used as a cream or shampoo at a 0.5–1% concentration.

Zinc pyrithione alone or in combination with other agents has been demonstrated to reduce erythema, scaling, burning/stinging sensation, and pruritus in patients with FSD, with excellent cosmetic results.
Zinc pyrithione is an antidandruff agent used in antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action.

Designed specifically to treat seborrheic dermatitis and dry scalp, Zinc pyrithione offers additional benefits: Zinc pyrithione is environmentally friendly, multifunctional (doubles as preserving agent), and flexible for various cosmetic formats.
Zinc pyrithione is compatible with most surfactants, additives and active ingredients used in cosmetic formulations.

Zinc pyrithione is an effective, practically nontoxic antidandruff active ingredient.
Zinc pyrithione is particularly suitable for the manufacture of antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action.

Zinc pyrithione is a highly effective antidandruff agent and an anti-acne active agent.
Zinc pyrithione is antimicrobial, soluble in surfactant systems.
Zinc pyrithione is used shampoos, shower products, liquid soaps, hair conditioners, hair styling products, antiperspirant & deodorants.

Zinc pyrithione, despite the recent upsurge in usage, has historically not been a hugely popular ingredient.
So very few independent clinical studies have been performed.
Zinc pyrithione main advantage is that it’s well tolerated, and so can be used frequently to control mild dandruff, but this hasn’t been properly evaluated.

Zinc pyrithione is one of the more recent active ingredients found in dandruff shampoos.
Designed to treat seborrheic dermatitis and dry scalp Zinc pyrithione is one of the most innovative areas of dandruff treatment on the market today.

Dandruff and seborrheic dermatitis can cause hair loss and thinning hair.
Zinc pyrithione is assumed that dandruff and seborrheic dermatitis (dandruff is a form of seborrheic dermatitis) are caused by a yeast (single cell fungus) on the skin, the Malassezia globose.
This is a fungus that occurs only on the scalp.

Often times, the problem will not go away on Zinc pyrithione own and requires continues treatment.
A well-known agent for this is shampoo with Ketoconazole in high concentration.
Multiple studies about the effectiveness of Zinc pyrithione have shown that Zinc pyrithione stimulates hair growth and helps against hereditary hair loss.

Ketoconazole is most well-known, but Zinc pyrithione is not the only proven anti-dandruff ingredient in shampoos which stimulates hair growth.
Zinc pyrithione has a similar effect as Ketoconazole.

Zinc pyrithione is also listed under the brand name 'Octopirox'.
In a study with 150 men who suffer from hereditary hair loss and dandruff, Ketoconazole and Zinc pyrithione were compared.

Excessive secretion of sebum, dandruff and seborrheic dermatitis are often linked with hair loss and hereditary hair loss.
The 150 men received a shampoo with 1% Ketoconazole or 1% Zinc pyrithione.
They had to use this shampoo 2 to 3 times per week for a duration of six months.

All treatments showed a reduction in itching and dandruff after 2 to 6 weeks.

If we take a look at the effect of the treatments on various hair growth parameters, we see the following figures (in percentages):
The severity of hair loss decreases (Ketoconazole: -17.3%, Zinc pyrithione: -16.5%)

The percentage of hairs in the growth phase increases (Ketoconazole 4.9%, Zinc pyrithione: 7.9%)
The effect on the hair diameter is increased by 5.4% with Ketoconazole and by 7.7% with Zinc pyrithione.

Thus, the study shows that Zinc pyrithione scores better in a number of areas in comparison to Ketoconazole.

Compared to Ketoconazole, Zinc pyrithione ensures an increase in the number of hairs in the growth phase (anagen phase) by more than 10% in 33% of people.
Zinc pyrithione gives 88% of the people thicker hair, despite hereditary hair loss, whereby this is 78% with Ketoconazole.
If we take a look at how many people experience a significant increase (more than 10%) of the hair diameter, this is 28% with Ketoconazole and as much as 34% with Zinc pyrithione (10% larger diameter means that the hair became 20% heavier).

The above results show that both Ketoconazole and Zinc pyrithione have a positive effect on multiple aspects of hair growth.
They have a similar effect on itch and dandruff.
Zinc pyrithione generally scores better when Zinc pyrithione comes to hair growth.

Zinc pyrithione is a preservative also used for Zinc pyrithione antifungal functions in anti-dandruff shampoos.
Zinc pyrithione is forbidden in organic.

Restriction in Europe:
Maximum concentration in ready-to-use preparation

Maximum content of secondary amine: 0.5%

Other restrictions:
Do not use with nitrosating systems
Minimum purity: 99%
Maximum content of secondary amine: 0.5% (applies to raw materials)
Maximum nitrosamine content: 50 micrograms / kg
Keep in containers without nitrite

If used as a conservator:

The maximum concentration allowed in ready-to-use cosmetic preparations is:
1.0% in Zinc pyrithiones to be rinsed
0,5% in other products

Applications of Zinc pyrithione:
Zinc pyrithione is quite beneficial in maintaining cosmetic and personal care products.
Zinc pyrithione can commonly be found in products like shampoos, cleansers, and hair masks.

Skin care:
Zinc pyrithione can be used to eliminate the bad odor from the surface of the skin.
Zinc pyrithione is a great preservative that helps in keeping skin care products free from bacterial growth.

Hair care:
Zinc pyrithione is one of the most common 'anti-dandruff' ingredients that is added to hair care products.
Zinc pyrithione is also good for preventing hair loss and split ends.

Cosmetic products:
In cosmetic products, Zinc pyrithione makes use of Zinc pyrithione antifungal properties to keep Zinc pyrithiones free from unwanted bacterial growth for a longer time.
The addition of Zinc pyrithione improves the quality of Zinc pyrithiones and makes them last longer.

Uses of Zinc pyrithione:
Zinc pyrithione is a broad-spectrum microbiocide/microbiostat, may be used in formulating antidandruff shampoo, hair keep and hair care, soap, etc.

Zinc pyrithione is used in shampoo, hair care, bath liquid, cosmetics, skin care products and washing products.
Zinc pyrithione has a unique effect in relieving skin itching, with excellent anti-itch effect, can effectively kill fungi on the skin, and has a special effect in eliminating body odor.
Zinc pyrithione is a safe, non-toxic, non-stimulating, ideally effective fungicide.

Zinc pyrithione anti-dandruff and anti-itch effect is superior to similar products.
Excellent solubility and compound performance, no precipitation or stratification when mixed with cosmetic raw materials.
Unique anti-dandruff mechanism, very low irritation, no hair loss, no hair breakage, safety is better than similar anti-dandruff anti-itch products.

Medicine:
Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
Zinc pyrithione also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor and vitiligo.

Paint:
Because of its low solubility in water (8 ppm at neutral pH), zinc pyrithione is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc pyrithione is an algaecide.

Zinc pyrithione is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc pyrithione is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc pyrithione is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges:
Zinc pyrithione is an antibacterial treatment for household sponges, as used by the 3M Corporation.

Clothing:
A process to apply zinc pyrithione to cotton with washable results was patented in the United States in 1984.
Zinc pyrithione is used to prevent microbe growth in polyester.

Textiles with applied zinc pyrithione protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.

Suggested use:
One in every three persons suffers from a problem related to their hair.
Whether Zinc pyrithione is dandruff, loss of hair, slow growth of hair or split ends, the masses are struggling to find a solution to their hair problems.

And in this search for the solution, they often find themselves looking at different shampoos and conditioners to solve the problem.
The issue is that most people end up selecting famous shampoos and conditioners, which may not necessarily be the most effective ones.

The most effective are not usually the ones which are famous (as anything can become famous if Zinc pyrithione is marketed and advertised well), they are the ones that have the appropriate ingredients.
Zinc pyrithione is the answer to that question.

Rate of Application:
Antidandruff hair keep: 0.1-0.8% active ingredient.
Antidandruff fixing agent: 0.05-0.2% active ingredient.
Antidandruff hair emulsion: 0.1-0.3% active ingredient.
Antidandruff hair supporting: 0.05-0.1% active ingredient.
Preservative: 0.2-0.5% active ingredient
Smell-eliminating agent: 0.2-0.5% active ingredient
Smell-eliminating scented soap: 0.2-0.5% active ingredient.

Consumer Uses:
Zinc pyrithione is used in the following products: cosmetics and personal care products and perfumes and fragrances.
Other release to the environment of Zinc pyrithione is likely to occur from: indoor use as processing aid.

Widespread uses by professional workers:
Zinc pyrithione is used in the following products: cosmetics and personal care products.
Zinc pyrithione is used for the manufacture of: chemicals.
Other release to the environment of Zinc pyrithione is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Zinc pyrithione is used in the following products: cosmetics and personal care products and perfumes and fragrances.
Zinc pyrithione is used for the manufacture of: chemicals.
Release to the environment of Zinc pyrithione can occur from industrial use: in processing aids at industrial sites and in the production of articles.

Benefits of Zinc pyrithione:
Zinc pyrithione has been specially developed to solve dandruff problems.
Zinc pyrithione prevents the scalp from flaking.

Zinc pyrithione contributes to the purification of hair roots from bacteria and fungi.
Zinc pyrithione is effective in eliminating the factors that cause itching at the roots of the hair.
Zinc pyrithione helps purify and cleanse the hair and scalp.

Shampoos, which have Zinc pyrithione as one of their ingredients, are known to eliminate dandruff.
However, before we learn how they cure dandruff, we must know what causes dandruff in the first place.

Dandruff is caused due to fungal growth, excess sebum secretion and local inflammations.
Often all these together cause dandruff.

Moreover, when the scalp’s skin renewal process is impaired, the excess dead cells form clumps on the head and seem like visible flakes to the eye, which are termed as dandruff.
Excess sebum also acts as an ingredient for the growth of fungus on the scalp, which increases the acids on the scalp that cause irritation and itching.

This leads to local inflammation, which enhances the growth of cells leading to the formation of flakes that seem like dandruff on the scalp.
The reason why shampoos with Zinc pyrithione can reduce and eliminate dandruff is that Zinc pyrithione is known to kill the fungus or the fungal infections that irritate the scalp.

Moreover, Zinc pyrithione is also well known for reducing hair loss and promoting the growth of hair.
Due to these many benefits, Zinc pyrithione is considered a great ingredient in shampoos.

Cures Dandruff:
Malassezia Globosa is not a friendly fungus found in your scalp.
Zinc pyrithione is the main reason behind scalp issues like dandruff and seborrheic dermatitis.

Your scalp becomes irritated and starts shedding tiny flakes.
In severe cases, you will notice inflammation, redness, and extremely itchy patches.
If you want to prevent your scalp from worsening, it’s essential to control the situation promptly.

Zinc pyrithione has antifungal properties, which will help you control the spread of Malassezia globosa.
Use an anti-dandruff shampoo containing Zinc pyrithione to fight dandruff.

Prevents Hair Loss:
Regardless of your gender and age, you may face hair fall, mostly caused due to dirt, dust, pollution, dandruff, excessive use of hair styling tools, etc.
Dandruff makes your scalp itchy, which leads to constant scratching, redness, and hair follicle damage.

Even though hair fall due to dandruff is not a significant concern but in people with androgenic alopecia (a condition that leads to baldness), Zinc pyrithione is a proven cure for reducing hair fall.
As Zinc pyrithione effectively works on dandruff and fungal infections, naturally, your hair loss decreases over time.

Boosts Hair Growth:
Zinc pyrithione encourages hair growth in many ways.
Zinc pyrithione reduces hair fall and increases the hair diameter.
Zinc pyrithione is often compared to Ketoconazole, which is a widely used ingredient for dandruff, but Zinc pyrithione provides better results for dandruff and fungal infections.

Ketoconazole + Zinc pyrithione is a combination of two antifungal medicines:
Ketoconazole and Zinc pyrithione which treat dandruff.

Ketoconazole kills fungi by destroying the fungal cell membrane.
Zinc pyrithione works by penetrating the cell membrane of the fungi to interfere with their energy metabolism and oxygen uptake.
This kills the fungi and clears up the infection.

Functions of Zinc pyrithione:

Preservative:
Inhibits the development of microorganisms in cosmetic products.

Anti dandruff:
Helps fight against dandruff.
Zinc pyrithione is an active, dandruff-fighting ingredient used in some of our shampoos.

Characteristics of Zinc pyrithione:
Zinc pyrithione is known for its bacteriostatic and fungistatic properties specifically working against Pityrosporum ovale, which lives on the skin and is associated with dandruff and other manifestations of flaking on the face and scalp.
Zinc pyrithione also reduced sebum production.

Appearance of Zinc pyrithione:
Zinc pyrithione has a white crystalline powder structure.

Resolution of Zinc pyrithione:
Zinc pyrithione has low solubility in water.
Zinc pyrithione dissolves better in some organic compounds.

Structure of Zinc pyrithione:
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers.
In solution, however, the dimers dissociate via scission of one Zn-O bond.

This compound was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.

Solubility of Zinc pyrithione:
The solubility of Zinc pyrithione is greatly dependent on the pH.
Generally speaking, Zinc pyrithione solubility in aqueous formulations is greater in the neutral and weakly alkaline ranges than in the acid range (formation of free acid).
Zinc pyrithione does however have adequate solubility in the usual pH range (pH5 - 8) in commercial surfactant solutions and alcohol-water mixtures.

Extraction method of Zinc pyrithione:
Zinc pyrithione is a particular salt that is also known as Octopirox and Piroctone ethanolamine.
Zinc pyrithione is a compound, which is often used to cure fungal infections.
Zinc pyrithione is a hydroxamic acid derivative Piroctone.

Action Mechanism of Zinc pyrithione:
Zinc pyrithione antifungal effect is thought to derive from Zinc pyrithione ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.

Origin of Zinc pyrithione:
Zinc pyrithione is of petrochemical origin and helps treat dandruff.
There is no natural alternative that comes close to being as effective as this.

History of Zinc pyrithione:
Zinc pyrithione has been used for around 40 years, first developed by Schwarzkopf-Henkel for use in anti-dandruff shampoo in the late 1970s.
All the initial clinical and safety studies were conducted by Hoechst AG, but this changed in the mid-1990s when other cosmetics companies began using the ingredient.

Zinc pyrithione was first submitted for approval to the European Union and United States FDA in the 1980s.
The ingredient was first approved for addition to the United States Pharmacopeia (USP) in 2008, after the FDA sought additional safety and effectiveness data in 2004.

Health effects of Zinc pyrithione:
Zinc pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several anti-dandruff shampoos and body wash gels.
In Zinc pyrithione industrial forms and strengths, Zinc pyrithione may be harmful by contact or ingestion.
Zinc pyrithione can in the laboratory setting trigger a variety of responses, such as DNA damage in skin cells.

Legal status of Zinc pyrithione:
Use of zinc pyrithione is prohibited in the European Union since December 2021.
Zinc pyrithione was considered safe for use in rinse-off and leave-in products of different tested concentrations, but due to environmental toxicity standard regulation was considered against potential alternatives – and as no submission was made for its use Zinc pyrithione was automatically prohibited.

Environmental concerns of Zinc pyrithione:
A large Swedish study shows that Zinc pyrithione is broken down in wastewater plants and does not release into waterways.
A Danish study shows that Zinc pyrithione biodegrades quickly, but that a risk of continuous leaching from boat paint may cause environmental toxicity.

Handling and storage of Zinc pyrithione:

Advice on safe handling:
Avoid contact with skin and eyes.
Avoid formation of dust and aerosols.

Advice on protection against fire and explosion:
Provide appropriate exhaust ventilation at places where dust is formed.

Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.

Storage stability:

Recommended storage temperature: 2 - 8 °C

Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids

Stability and reactivity of Zinc pyrithione:

Reactivity:
No data available

Chemical stability:
Stable under recommended storage conditions.

Possibility of hazardous reactions:
No data available

Conditions to avoid:
No data available

Incompatible materials:
Strong acids and oxidizing agents, Strong oxidizing agents

Health Effect of Zinc pyrithione:
If used as a preservative, Zinc pyrithione should be used at a maximum rate of 1.0% in rinsed products and at a maximum rate of 0.5% in other products.
Zinc pyrithione should not be used together with nitrosamine-forming agents.

Nitrosamines are carcinogenic substances.
The impurity rate should be 99%.

The maximum amount of secondary amine should be 0.5%.
The maximum amount of nitrosamine cannot exceed 50 micrograms/kg. The raw material should be stored in nitrite-free packaging.

Zinc pyrithione is a synthetic component.
They are raw materials produced using various processes under laboratory conditions.

These are raw materials obtained without using animal sources (propolis, honey, beeswax, lanolin, collagen, snail extract, milk, etc.).
Zinc pyrithione is a criterion that should be taken into consideration for those who want to use vegan products.

Studies have concluded that different effects can be seen on each skin type.
For this reason, the allergy/irritation effect may vary from person to person.
However, Zinc pyrithione causes stinging, tingling, itching, redness and irritation, especially in people with sensitive skin types.

Precaution of Zinc pyrithione:
However, just like excess of anything is bad, too much of Zinc pyrithione can be bad for the scalp too.
This is precisely why shampoos with Zinc pyrithione have a very minor amount of Zinc pyrithione so that its side effects do not affect the scalp in any way.

Zinc pyrithione should be kept in mind that shampoos with Zinc pyrithione should not be used more than twice a week, unlike other daily use shampoos that don’t have this ingredient.
One of the biggest side effects of Zinc pyrithione is that Zinc pyrithione can cause irritation and itchiness on the head.

First aid measures of Zinc pyrithione:

General advice:
Consult a physician.

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.

In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures of Zinc pyrithione:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from Zinc pyrithione:
Carbon oxides
Nitrogen oxides (NOx)

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.

Further information:
No data available

Accidental release measures of Zinc pyrithione:

Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
Avoid dust formation.

Avoid breathing vapors, mist orgas.
Ensure adequate ventilation.

Evacuate personnel to safe areas.
Avoid breathing dust.

Environmental precautions of Zinc pyrithione:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Pick up and arrange disposal without creating dust.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.

Identifiers of Zinc pyrithione:
CAS Number: 68890-66-4
ChemSpider: 45574
ECHA InfoCard: 100.065.957
MeSH: Piroctone+olamine
PubChem CID: 50258
UNII: A4V5C6R9FB
CompTox Dashboard (EPA): DTXSID4046735
InChI: InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
Key: BTSZTGGZJQFALU-UHFFFAOYSA-N
InChI=1/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
Key: BTSZTGGZJQFALU-UHFFFAOYAP
SMILES: CC1=CC(=O)N(C(=C1)CC(C)CC(C)(C)C)O.C(CO)N

CAS NO: 68890-66-4
EC NO: 272-574-2

Synonym(s): 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt
Empirical Formula (Hill Notation): C14H23NO2 · C2H7NO
CAS Number: 68890-66-4
Molecular Weight: 298.42
EC Number: 272-574-2
MDL number: MFCD01690792
PubChem Substance ID: 329757760
NACRES: NA.24

Product Number: P2178
Purity / Analysis Method: >97.0%(T)(HPLC)
Molecular Formula / Molecular Weight: C14H23NO2·C2H7NO = 298.43
Physical State (20 deg.C): Solid
Storage Temperature: 0-10°C
Condition to Avoid: Heat Sensitive
CAS No: 68890-66-4
Related CAS No: 50650-76-5
Reaxys Registry Number: 7503297
PubChem Substance ID: 253662076
Merck Index (14): 7502
MDL Number: MFCD01690792

Properties of Zinc pyrithione:
Chemical formula: C16H30N2O3
Molar mass: 298.421

Molecular weight: 298.43
Formula: C14H23NO2·C2H7NO
Purity: >97.0%(T)(HPLC)
Color/Form: White to Almost white powder to crystal
MDL: MFCD01690792
Melting point: 136 °C
Flash point: 136 °C
HS code: 2933790090

grade: analytical standard
Quality Level: 100
Assay: ≥99.0% (HPLC)
shelf life: limited shelf life, expiry date on the label

technique(s)
HPLC: suitable
gas chromatography (GC): suitable

application(s):
agriculture
environmental

format: neat
storage temp.: 2-8°C
SMILES string: NCCO.CC(CC1=CC(C)=CC(=O)N1O)CC(C)(C)C
InChI: 1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
InChI key: BTSZTGGZJQFALU-UHFFFAOYSA-N

Molecular Weight: 298.42 g/mol
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 5
Exact Mass: 298.22564282 g/mol
Monoisotopic Mass: 298.22564282 g/mol
Topological Polar Surface Area: 86.8Ų
Heavy Atom Count: 21
Complexity: 371
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Specification of Zinc pyrithione:
Appearance: White or slightly yellow crystalline powder
Odor: Characteristic

Solubility:
Water (0.10g +10ml):non-soluble
Methanol (1.00g + 10ml): soluble

Purity(HPLC) %: ≥99.0
PH value(1% aqueous suspension,20℃): 8.5-10.0
Melting Point ℃: 130-135
Drying loss %: ≤0.3
Ash(SO4) %: ≤0.2
Particle size distribution: D(0.5): 30-50um Provide a profile representative of the raw material
E1% (1cm) at 317 nm expressed an dried substance: 214-236
Ethanolamine %: 20.0-21.0
Nitrosamine content PPB: ≤50
Heavy metals(Pb,As,Cd,Co,Cr,Hg,Ni,Sb) PPM: ≤10
Hexane(GC) PPM: ≤300
Ethyl acetate(GC) PPM: ≤5000

Names of Zinc pyrithione:

Regulatory process names:
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl) 2-pyridon, monoethanolamine salt
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compd. with 2-aminoethanol (1:1)
Kopirox
Octopirox
Piroctone ethanolamine salt
Piroctone olamine
Bio Boost 2300EX
Blo Boost 2300EX
Pyrithione zinc
Pyrithione zinc
pyrithione zinc
Pyrithione zinc (Zinc pyrithione)
pyrithione zinc; (T-4)-bis[1-(hydroxy-κO)pyridine-2(1H)-thionato-κS]zinc
Zinc pyrithione
Zinc Pyrithlone
Zink Pyrithione (zinc omadine)

IUPAC names:
(RS)-1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)-2(1H)-PYRIDINONE ETHANOLAMINE (1:1)
1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt
1-hydroxy-4-methyl-6-(2,4,4-trimethylpently)pyridin-2-(1H)-one compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-1,2-dihydropyridin-2-one; 2-aminoethan-1-ol
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one - 2-aminoethanol (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one,compound with 2-aminoethanol (1:1)
1-hydroxy-4methyl-6-(2,4,4-trimethylphenyl)pyridine-2(1H)-one, compound with 2-aminoethanol(1:1)
2-aminoethanol; 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
2-amminoetanolo; 1-idrossi-4-metil-6-(2,4,4-trimethylpentyl) pyridin-2-one
Octopirox
Piroctone Olamine
Piroctone Olamine
Piroctone olamine
1-oxidopyridine-6-thiolate, zinc (II) cation
2-Mercaptopyridine N-Oxide Zinc Salt
Bis [1-hydroxy-2(1H)-pyridinethionato-O,S](T-4)-zinc
bis(1-hydroxy-2(1h)-pyridinethionato)zinc
bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4) zinc
Bis(1-hydroxy-2(1H)-pyridinthionato-O,S) zinc
bis(2-pyridylthio)zinc 1,1'-dioxide
bis[1-hydroxy-2-(1H)-pyridine-thionato]zinc
Kopthione Zn
Mercaptopyridine N-oxide zinc salt, Pyrithione
Mercaptopyridine N-oxidezinc salt
Pyrithione zinc
pyrithione zinc
pyrithione zinc`
Zinc 1-oxidopyridin-1-ium-2-thiolate
zinc 1-oxidopyridin-1-ium-2-thiolate
Zinc 2-pyridinethiol-1-oxide
zinc bis(2-thioxopyridin-1(2H) -olate)
zinc bis(2-thioxopyridin-1(2H)-olate)
Zinc pyridinethione
Zinc pyrithion
Zinc Pyrithione
Zinc pyrithione
zinc(2+) bis(2-sulfanylidene-1,2-dihydropyridin-1-olate)
ZINC, BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO)- (6CI,7CI,8CI)
zinc;1-oxidopyridin-1-ium-2-thiolate

Translated names:
Cinko piritionas (lt)
Piirition taż-żingu (Piirition taż-żingu) (mt)
Pirition cink (cinkov pirition) (hr)
Pirition cink (cinkov pirition) (sl)
Pirition-cink (Cink-pirition) (hu)
Piritiona de cinc (es)
Piritiona-zinco (piritiona de zinco) (pt)
Piritioncinks (cinka piritions) (lv)
Piritionă de zinc (ro)
Pirytionian cynku (pl)
Pyrithion-Zink (Zink-Pyrithion) (de)
Pyrithione zinc (Zinc pyrithione) (no)
Pyrithione zincique (pyrithione de zinc) (fr)
pyrithionzink (da)
Pyrithionzink (zinkpyrithion) (nl)
Pyritionisinkki (sinkkipyritioni) (fi)
Tsinkpüritioon (et)
Zinco piritione (piritione zincica) (it)
zink-1-oxo-1λ5-pyridin-2-thiolát (cs)
zinkium-pyritión (sk)
Zinkpyrition (Pyritionzink) (sv)
Άλας πυριθειόνης με ψευδάργυρο (Zinc pyrithione) (el)
Цинков пиритион (bg)
Picroctone Olamine
Piroctone olamine

Other identifiers:
1021487-49-9
109702-19-4
118480-78-7
1192-70-7
1199553-62-2
1320-68-9
1323439-04-8
13463-41-7
14376-32-0
15686-64-3
162400-43-3
16782-00-6
17652-47-0
186322-74-7
192458-89-2
208398-70-3
226883-65-4
244778-79-8
266692-38-0
31089-48-2
3138-01-0
318995-78-7
35430-20-7
3590-23-6
3865-77-8
39412-61-8
51148-10-8
51406-57-6
55172-61-7
613-333-00-7
74261-71-5
943428-71-5
68890-66-4
ZINC PYRITHIONE (ANTIDANDRUFF)
Zinc Pyrithione (Antidandruff) is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chem/IUPAC Name: Pyridine-2-thiol-1-oxide, zinc complex (2:1)
Chemical formula: C10H8N2O2S2Zn



SYNONYMS:
Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc Pyrithione, 48% Aqueous Dispersion, Zinc Pyrithione 48% Aqueous Dispersion, Zinc Pyritione 48%, Zinc Pyrithione, T/N: Zinc Omadine 48% FPS, Zinc Pyridinethione, Zinc Omadine, Pyrithione Zinc, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT,



Zinc Pyrithione (Antidandruff) is a chemical compound consiting of zinc and pyrithione.
Zinc Pyrithione (Antidandruff) is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.


Zinc Pyrithione (Antidandruff) can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Pyrithione (Antidandruff) or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.


In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione (Antidandruff) is used to treat dandruff and seborrheic dermatitis.
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.


Zinc Pyrithione (Antidandruff) is one of the most popular anti-dandruff ingredients contributing bactericide-fungicide action in shampoos, conditioners, and leave-on products.
Zinc Pyrithione (Antidandruff) is a dispersion of fine particles that enhances the anti-dandruff efficacy and cosmetic performance attributes.


Zinc Pyrithione (Antidandruff) effectively fights against Malassezia spp. yeast, which is the primary factor in the development of dandruff on the scalp.
Malassezia is a lipid-loving organism and is therefore attracted to the lipophilically coated Zinc Pyrithione (Antidandruff), offering enhanced efficacy of the it, as well as counteracting some negative effects of shampooing such as dry scalp and residue build up on the hair.


Zinc Pyrithione (Antidandruff) (also called pyrithione zinc or ZPT) is known as a “coordination complex” of zinc and pyrithione.
Zinc Pyrithione (Antidandruff) offers bactericide-fungicide efficacy.
Zinc Pyrithione (Antidandruff) is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.


Zinc Pyrithione (Antidandruff) acts as an anti-dandruff and odor-controlling agent.
Zinc Pyrithione (Antidandruff), also known as Pyrithione Zinc, is an antibacterial, antimicrobial, and antifungal agent that can be used to treat dandruff, scalp psoriasis, and acne.


Zinc Pyrithione (Antidandruff) is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (Antidandruff) is known for its ability to fight dandruff and promote a healthy scalp.


Zinc Pyrithione (Antidandruff) is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc Pyrithione (Antidandruff) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.


Due to low solubility, Zinc Pyrithione (Antidandruff) released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.
Zinc Pyrithione (Antidandruff) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.


Zinc Pyrithione (Antidandruff) has the ability to inhibit the growth of yeast, which is a major cause of dandruff.
If you're struggling with dandruff or other scalp issues, look for hair care products containing Zinc Pyrithione (Antidandruff) to help alleviate your symptoms and promote a healthy scalp.


So while it does draw from the naturally occurring metal, Zinc Pyrithione (Antidandruff) is ultimately produced in a lab.
Zinc Pyrithione (Antidandruff) is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Pyrithione (Antidandruff) can effectively prevent precipitation and double the antimicrobial effect.


Zinc Pyrithione (Antidandruff), also commonly known as pyrithione zinc is derived from the chemical zinc, has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Pyrithione (Antidandruff) can inhibit the growth of yeast, which is a main factor in dandruff.


Zinc Pyrithione (Antidandruff) offers bactericide-fungicide efficacy.
Zinc Pyrithione (Antidandruff) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione (Antidandruff) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.


Zinc Pyrithione (Antidandruff) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Zinc Pyrithione (Antidandruff) is known for its ability to fight dandruff and promote a healthy scalp.


This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.
Zinc Pyrithione (Antidandruff) is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and
bacterial (gram-positive & gram-negative).


Zinc Pyrithione (Antidandruff) is a fungistatic and baceriostatic compound that has a variety of uses.
Zinc Pyrithione (Antidandruff) is a chemical compound derived from the natural element Zinc.
Zinc Pyrithione (Antidandruff) was first developed in the 1930s, then synthesized by E. Shaw in 1950.


For instance, Zinc Pyrithione (Antidandruff)’s an essential element in kitchen sponges, preventing the growth of mould.
Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (Antidandruff) is known for its ability to fight dandruff and promote a healthy scalp.


Zinc Pyrithione (Antidandruff) is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (Antidandruff) inhibits the growth of a broad spectrum of both Gram-positive and Gram-negative bacteria.


In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer.
Zinc Pyrithione (Antidandruff) also inhibits the growth of fungi, yeast, mold, and algae.
Zinc Pyrithione (Antidandruff) is a mixture of ultra-fine particles of zinc pyrithione (ZPT), a dispersant and a stabilizing agent.



USES and APPLICATIONS of ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) has antibacterial, antimicrobial, and antifungal properties, which is why it’s often used in dandruff shampoo.
Other uses of Zinc Pyrithione (Antidandruff) include additive in antifouling outdoor paints and algaecide.
While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione (Antidandruff) has been reported for decades.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione (Antidandruff) works by targeting both local fungi and bacteria residing on the scalp.
Zinc Pyrithione (Antidandruff) can inhibit the growth of yeast, which is a main factor in dandruff.


As the name suggests, Zinc Pyrithione (Antidandruff) is derived from the chemical element zinc, and it’s used in a variety of hair and skin care products.
Zinc Pyrithione (Antidandruff) is a common ingredient in antidandruff shampoos, but it can also be effective at treating psoriasis, eczema, and acne.
This is because of Zinc Pyrithione (Antidandruff)'s antimicrobial, antibacterial, and antifungal properties.


Zinc Pyrithione (Antidandruff)’s used as an ingredient in skin care and hair products because of its antibacterial, antifungal and antimicrobial properties.
Zinc Pyrithione (Antidandruff) is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione (Antidandruff) is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.


In addition, an important characteristic of this molecule is that Zinc Pyrithione (Antidandruff) is efficacious against various bacteria species associated with producing odor on the skin.
Zinc Pyrithione (Antidandruff) is a fungistatic and bacteriostatic compound that has a variety of uses.


Zinc Pyrithione (Antidandruff) is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione (Antidandruff) is widely used as a fungicide for paints and plastics.
Zinc Pyrithione (Antidandruff) has unique advantages in environmental friendliness and sterilization persistence.


Zinc Pyrithione (Antidandruff) is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).
Zinc Pyrithione (Antidandruff) is also often used in kitchen sponges as an antibacterial treatment.


Zinc Pyrithione (Antidandruff) has been used topically for inflammatory skin conditions for more than 50 years.
Zinc Pyrithione (Antidandruff) has become one of the most common ingredients for improving issues like dandruff and seborrheic dermatitis.
Zinc Pyrithione (Antidandruff) can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.


As the name suggests, Zinc Pyrithione (Antidandruff) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.
Pharmaceutical Applications of Zinc Pyrithione (Antidandruff): Zinc Pyrithione (Antidandruff) is a regulator of keratinization, has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).


Zinc Pyrithione (Antidandruff) is used as a bactericide for coatings and plastics, etc.
Zinc Pyrithione (Antidandruff) is used in shampoos to remove dandruff, and can inhibit the growth of Gram-positive and negative bacteria and molds.
Zinc Pyrithione (Antidandruff) can effectively care for the hair, delay the aging of the hair, and control the generation of gray hair and hair loss.


Today, Zinc Pyrithione (Antidandruff)’s added to a range of skin and hair products, including shampoos, face washes and creams.
As the name implies, Zinc Pyrithione (Antidandruff) is generated from the chemical element zinc and is utilized in several haircare and skincare products.
Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione (Antidandruff) is suitable for outdoor coatings and other products that protect against mold and algae.


Look at the ingredient list of any product made to fight fungal or bacterial infections that affect the skin and you’re sure to see Zinc Pyrithione (Antidandruff).
Zinc Pyrithione (Antidandruff) is used in a variety of hair and skin care products.


In addition, Zinc Pyrithione (Antidandruff) is an effective algaecide.
Zinc Pyrithione (Antidandruff) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
Zinc Pyrithione (Antidandruff) acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.


Zinc Pyrithione (Antidandruff) can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.


As an anti-mildew agent, Zinc Pyrithione (Antidandruff) also has some applications on fabrics.
Therefore, Zinc Pyrithione (Antidandruff) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


Zinc Pyrithione (Antidandruff)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.
For shampoo to remove dandruff, Zinc Pyrithione (Antidandruff) can inhibit the growth of gram-positive and negative bacteria and mold.


Therefore, Zinc Pyrithione (Antidandruff) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Zinc Pyrithione (Antidandruff) has a strong killing effect on fungi and bacteria, can effectively kill the fungus that produces dandruff, and has an anti-dandruff effect.


Zinc Pyrithione (Antidandruff) is used in skincare, shampoos, conditioners and leave-on products.
Zinc Pyrithione (Antidandruff) is an antifungal, antibacterial, and antimicrobial agent for an anti-dandruff shampoo.
Zinc Pyrithione (Antidandruff) is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione (Antidandruff) is used to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione (Antidandruff) is a highly effective bactericide-fungicide, the anti-dandruff agent establishes the market standard for any active ingredient solutions in anti-dandruff shampoos.


Zinc Pyrithione (Antidandruff)'s high antimicrobial efficacy combined with the acceptability for human use has made it the agent of choice for anti-dandruff shampoo manufacturers worldwide.
Study shows that using a medicated soap that contains 2% may help clear acne, making Zinc Pyrithione (Antidandruff) a great active for black soap, cold or hot process soap.


Zinc Pyrithione (Antidandruff) anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione (Antidandruff) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.


Zinc Pyrithione (Antidandruff) has strong killing power on fungi and bacteria, can effectively kill the fungi that produce dandruff, and play an anti-dandruff effect.
Zinc Pyrithione (Antidandruff), as an anti-dandruff agent with a long history, is widely known in the shampoo industry and used by many well-known brands.


-Zinc Pyrithione (Antidandruff) is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc Pyrithione (Antidandruff) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth

1. Due to low solubility, Zinc Pyrithione (Antidandruff) released from the topical formulations is deposited and retained relatively well onto the target skin surfaces

2. Other uses of Zinc Pyrithione (Antidandruff) include additive in antifouling outdoor paints and algaecide.
While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione (Antidandruff) has been reported for decades.
Zinc Pyrithione (Antidandruff) is not shown to have any significant estrogenic activity according to the in vivo and in vitro assays


-Zinc Pyrithione (Antidandruff) is used in cream:
Seborrheic dermatitis often affects the scalp, but it can also cause rough, scaly patches on the skin.
Zinc Pyrithione (Antidandruff) is used to treat seborrheic dermatitis or psoriasis on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2% Zinc Pyrithione (Antidandruff) followed by a moisturizer.
You can also use Zinc Pyrithione (Antidandruff) daily by applying it in a thin layer to the affected area.


-Zinc Pyrithione (Antidandruff) is used face wash:
Zinc Pyrithione (Antidandruff) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione (Antidandruff) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2% Zinc Pyrithione (Antidandruff) may help clear acne.


-Zinc Pyrithione (Antidandruff) is used inshampoo:
Zinc Pyrithione (Antidandruff) shampoo is found in many common antidandruff shampoos.
Zinc Pyrithione (Antidandruff)’s antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.



HOW TO USE ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) is easily found in many drugstore and supermarket shampoo products.
There are also leave-in treatments available from retail haircare lines.

-Use in an anti-dandruff shampoo:
Zinc Pyrithione (Antidandruff) is most often found in anti-dandruff shampoos.
For best results, you should wet your hair and massage the shampoo into your scalp.

Let Zinc Pyrithione (Antidandruff) sit for approximately one minute (or as instructed on the shampoo label) before shampooing the rest of your hair and then rinse out.
Usage will depend on the sensitivity and state of your scalp.

While many shampoos containing Zinc Pyrithione (Antidandruff) can be used daily, I typically recommend using it at least two to three times per week.
For some individuals dealing with seborrheic dermatitis or dandruff, I often recommend washing the scalp daily or every other day to help eliminate the build-up of oils or dead skin, which may contribute to scaling or flaking.

If someone is concerned about dryness of the scalp, it is okay to use a Zinc Pyrithione (Antidandruff) shampoo a few days per week and a non-medicated shampoo on the alternating days.


-Use Zinc Pyrithione (Antidandruff) in a hydrating conditioner:
Conditioners with Zinc Pyrithione (Antidandruff) can help fight dandruff, itch, and flaking while restoring scalp balance and providing hydration.
After shampooing, massage the conditioner into your scalp and hair and cover it with a shower cap.

Leave on for 3 minutes and wash out.
Follow the instructions on the label for the best results.


-Relieve itch and flakes with a serum:
Serums with Zinc Pyrithione (Antidandruff) are great for those with oily scalps or severe flaking and dandruff.
Apply Zinc Pyrithione (Antidandruff) to the scalp in between washes to help with itch and flakes.
Follow the directions on Zinc Pyrithione (Antidandruff), but most can be applied several times a day.


-Apply Zinc Pyrithione (Antidandruff) in a scalp-soothing leave-in cream:
If your scalp tends to get dry, a leave-in cream is often more soothing and moisturizing than a serum.
The creams are often infused with hydrating products like vitamin E and argan oil to protect and moisturize, while the Zinc Pyrithione (Antidandruff) relieves dandruff, itch, and irritation.



ADVANTAGES OF ZINC PYRITHIONE (ANTIDANDRUFF):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Zinc Pyrithione (Antidandruff) helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Zinc Pyrithione (Antidandruff) is used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



INCLUDES ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) is found in several skin and hair products, including the following:

*Zinc Pyrithione (Antidandruff) shampoo:
Shampoos containing Zinc Pyrithione (Antidandruff) is used for the ingredient’s anti-dandruff properties.
Zinc Pyrithione (Antidandruff) helps kill fungus or bacteria that causes red, itchy and flaky scalp.

*Zinc Pyrithione (Antidandruff) face wash:
Because of its antimicrobial properties, Zinc Pyrithione (Antidandruff) face wash helps improve acne and relieve symptoms of skin issues, such as eczema, seborrheic dermatitis and psoriasis.

*Zinc Pyrithione (Antidandruff) soap:
Like face washes, body soaps medicated with Zinc Pyrithione (Antidandruff) have antifungal, antibacterial and antimicrobial effects.
Skin conditions like seborrheic dermatitis affect areas of the body beyond the face, like the upper chest, back, neck and groin.
For these issues and others caused by inflammation, Zinc Pyrithione (Antidandruff) soap may be helpful.

*Zinc Pyrithione (Antidandruff) cream:
For rough patches on the skin or dry skin caused by conditions like psoriasis, Zinc Pyrithione (Antidandruff) cream can be used for its moisturizing effects.



TYPE OF INGREDIENT OF ZINC PYRITHIONE (ANTIDANDRUFF):
Antifungal, antimicrobial, and antibacterial properties


MAIN BENEFITS OF ZINC PYRITHIONE (ANTIDANDRUFF):
Treats dandruff, soothes scalp irritation, regulates oil production, and prevents itching.


WHO SHOULD USE ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) is best for those experiencing dandruff or seborrheic dermatitis, which may be associated with an oily scalp.
It is best to consult a dermatologist to determine the cause of your scalp flakes or irritation before using Zinc Pyrithione (Antidandruff).


HOW OFTEN CAN YOU USE ZINC PYRITHIONE (ANTIDANDRUFF):
Shampoos containing Zinc Pyrithione (Antidandruff) can be used daily, and those individuals dealing with seborrheic dermatitis or dandruff are often advised to cleanse daily.
If the scalp is dry, it is okay to use a Zinc Pyrithione (Antidandruff) shampoo two to three days per week and a non-medicated shampoo on alternating days.


ZINC PYRITHIONE (ANTIDANDRUFF) WORKS WELL WITH:
Selenium sulfide, another ingredient commonly found in dandruff shampoos stronger than Zinc Pyrithione (Antidandruff).
Additionally, some individuals may alternate with other anti-dandruff ingredients, such as ketoconazole, an antifungal ingredient.


DON’T USE WITH ZINC PYRITHIONE (ANTIDANDRUFF):
There are no known ingredients that negatively interfere with Zinc Pyrithione (Antidandruff); however, it is advised that you speak to a medical professional before using if you are pregnant or nursing.



BENEFITS/USES OF ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) can be used daily as an ingredient in an over-the-counter or prescription product.
If it causes dryness to the scalp or skin, rotate using the Zinc Pyrithione (Antidandruff) product with a non-medicated product.
The top benefits and uses of Zinc Pyrithione (Antidandruff) include:


1. Zinc Pyrithione (Antidandruff) has Antibacterial Effects
Research published in the Journal of Drugs in Dermatology indicates that the particles in Zinc Pyrithione (Antidandruff) interact with surface fungal and bacteria cells to control their population.
By fighting the growth of these invaders, Zinc Pyrithione (Antidandruff) improves conditions that impact the skin and scalp.


2. Zinc Pyrithione (Antidandruff) works as an Antifungal Agent
Zinc Pyrithione (Antidandruff) is the most widely used ingredient in medicated shampoos and soaps because of its powerful antifungal effects.
Research shows that Zinc Pyrithione (Antidandruff) is delivered as a micro-particle into the inner layers of skin, allowing it to inhibit fungal activity and improve inflammatory skin conditions, such as fungal acne and dandruff.


3. Zinc Pyrithione (Antidandruff) reduces Dandruff
A 2018 study published in Scientific Reports found that Zinc Pyrithione (Antidandruff) inhibits the growth of M. restricta, a fungus that commonly causes dandruff.

Researchers found that Zinc Pyrithione (Antidandruff) treatment significantly reduced the expression of enzymes that’s activity contribute to the survival of these fungi on human skin.
Zinc Pyrithione (Antidandruff) also proved to improve dandruff by increasing cellular zinc levels.


4. Zinc Pyrithione (Antidandruff) may Improve Hair Growth
A controlled trial published in the British Journal of Dermatology found that 1 percent Zinc Pyrithione (Antidandruff) shampoo improved hair growth when it was used daily for 26 weeks.
Researchers believe that this may be due to Zinc Pyrithione (Antidandruff)’s antifungal and antibacterial effects.


5. Zinc Pyrithione (Antidandruff) soothes Skin Irritation and Itchiness
Research indicates that Zinc Pyrithione (Antidandruff) inhibits the growth of fungus and antimicrobials that cause uncomfortable skin conditions.
Zinc Pyrithione (Antidandruff) helps relive itchiness, redness and irritation that often come with inflammatory conditions, like fungal acne, dandruff, psoriasis and seborrheic dermatitis.


6. Zinc Pyrithione (Antidandruff) regulates Oil Production
Conditions like seborrheic dermatitis can cause skin dryness and oiliness at the same time.
By inhibiting the growth of yeast that causes this condition, Zinc Pyrithione (Antidandruff) helps regulate oil production in the skin and improve the greasiness that can be associated with it.



FUNCTIONS OF ZINC PYRITHIONE (ANTIDANDRUFF):
*Anti-dandruff
*Antiseptic
*Antibacterial
*Anti-Seborrheic
*Anti-Sebum
*Hair conditioning
*Preservative



BENEFITS OF ZINC PYRITHIONE (ANTIDANDRUFF) FOR HAIR:
The benefits of Zinc Pyrithione (Antidandruff) extend beyond the skin of the scalp. By improving the health of the scalp, the health of the hair benefits as well.
Zinc Pyrithione (Antidandruff) has the power to treat a variety of issues, including dandruff, itchiness, acne, and scalp psoriasis by targeting the yeast/fungus that is causing the problem.


*Fights dandruff-causing fungus:
The antifungal, antimicrobial, and antibacterial properties stop dandruff at its source.

Zinc Pyrithione (Antidandruff) is naturally anti-inflammatory and is also antifungal and antibacterial,.
Since dandruff is caused directly by an excessive amount of fungus and yeast living on the scalp, by adding the Zinc Pyrithione (Antidandruff), you decrease the fungal buildup on the scalp and alleviate the inflammation causing the dandruff.


*Prevents itching:
Dandruff is one of the leading causes of scalp itchiness.
By preventing dandruff and eliminating the irritating yeast/fungus that causes it, Zinc Pyrithione (Antidandruff) provides itch relief quickly.


*Regulates oil production:
Zinc Pyrithione (Antidandruff) can control the oil production and dandruff often found in those with seborrheic dermatitis.


*Improves overall scalp health:
Dandruff disrupts the health of the scalp by clogging follicles with flakes and by causing inflammation and irritation.
Zinc Pyrithione (Antidandruff) is able to improve the overall health of the scalp by preventing and treating dandruff.


*Promotes hair growth:
Zinc Pyrithione (Antidandruff) has the potential to impact hair growth.
Since a number of thinning hair and hair loss concerns are related to the scalp, Zinc Pyrithione (Antidandruff) can help clear dead skin cells or conditions that prevent hair growth (clogged hair follicles, psoriasis, etc.) and thus promote fuller, healthier hair.

Garshick agrees and points out a study that showed that daily use of 1 percent Zinc Pyrithione (Antidandruff) shampoo over 26 weeks showed an improvement in hair growth.


*Improves overall appearance of hair:
The overall appearance of the hair is heavily influenced by the oiliness of the scalp and the thickness of the hair.
By regulating oil production and encouraging new growth, Zinc Pyrithione (Antidandruff) can boost the overall appearance of the hair.



WHAT HAIR TYPES CAN USE ZINC PYRITHIONE (ANTIDANDRUFF)?
Our experts agree that Zinc Pyrithione (Antidandruff) is safe for all hair types but would be most beneficial for those experiencing dandruff, seborrheic dermatitis, or other scalp conditions that are aggravated by fungus/yeast.

Some formulations of shampoos and topical scalp products include Zinc Pyrithione (Antidandruff) and hydrating and moisturizing ingredients that would be better for those with dry or color-treated hair.

If you don't have dandruff or other scalp conditions, skipping the products with Zinc Pyrithione (Antidandruff) is best.
The only downside is that Zinc Pyrithione (Antidandruff) could ultimately dry out the hair and scalp slightly and upset a healthier scalp microbiome if there is no dandruff or inflammation.

Zinc Pyrithione (Antidandruff) is always best to speak with a medical professional to evaluate the scalp and determine the best course of treatment.
For those with dry or sensitive skin, it is best to slowly incorporate Zinc Pyrithione (Antidandruff) into a routine and use caution as some dryness and irritation may occur.



BENEFITS OF ZINC PYRITHIONE (ANTIDANDRUFF) FOR HAIR:
Zinc Pyrithione (Antidandruff) is an active ingredient commonly used in anti-dandruff shampoos and personal care products to treat scalp conditions such as seborrheic dermatitis and psoriasis.
Zinc Pyrithione (Antidandruff) is a coordination complex of zinc that contains pyrithione, a biocide with antibacterial and antifungal properties.

Zinc Pyrithione (Antidandruff) works by slowing down the growth of skin cells and reducing the production of yeast, which is a major contributor to dandruff and other scalp conditions.
Zinc Pyrithione (Antidandruff) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.

In addition to its use in personal care products, Zinc Pyrithione (Antidandruff) is also used as an industrial biocide to control the growth of algae and other microorganisms in water-based systems such as paints, coatings, and adhesives.

Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos and is known for its ability to effectively combat dandruff and other scalp issues.
But Zinc Pyrithione (Antidandruff) has many other benefits for hair as well.

Here are some of the benefits and uses of Zinc Pyrithione (Antidandruff) for hair:

*Controls Dandruff:
Zinc Pyrithione (Antidandruff) is primarily used to control dandruff, which is caused by an overgrowth of a type of yeast called Malassezia on the scalp.
Zinc Pyrithione (Antidandruff) helps to slow down the growth of this yeast, reducing the amount of dandruff on the scalp.


*Soothes Scalp Irritation:
Zinc Pyrithione (Antidandruff) has anti-inflammatory properties that can help to soothe an irritated or itchy scalp.
This makes Zinc Pyrithione (Antidandruff) an effective ingredient for those with sensitive scalps.


*Promotes Hair Growth:
Zinc Pyrithione (Antidandruff) can also help to promote hair growth by reducing inflammation and providing a healthy environment for hair follicles to grow.


*Fights Hair Loss:
Zinc Pyrithione (Antidandruff) can help to fight hair loss by reducing the inflammation in the scalp that can lead to hair shedding.


*Improves Hair Texture:
Zinc Pyrithione (Antidandruff) can help to improve the texture and appearance of hair by removing build-up and excess oil from the scalp, which can weigh down hair and make it look dull.


*Suitable for All Hair Types:
Zinc Pyrithione (Antidandruff) is safe for use on all hair types, including color-treated hair, as it is a gentle yet effective ingredient.


Overall, Zinc Pyrithione (Antidandruff) is an effective ingredient for promoting a healthy scalp and hair growth, making it a great choice for those dealing with dandruff, hair loss, or other scalp issues.



HOW DOES ZINC PYRITHIONE WORK?
Zinc Pyrithione (Antidandruff) works by targeting the fungus Malassezia, which is a common cause of dandruff and other scalp conditions.
Malassezia is a type of yeast that naturally lives on the scalp and feeds on oils secreted by the hair follicles.

Zinc Pyrithione (Antidandruff) works by disrupting the cell membranes of Malassezia, causing it to die off and reducing its ability to reproduce.
In addition to its antifungal properties, Zinc Pyrithione (Antidandruff) also has antibacterial properties that help to eliminate the bacteria that can contribute to scalp odour.

Zinc Pyrithione (Antidandruff) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
Zinc Pyrithione (Antidandruff) works by inhibiting the production of cytokines, which are proteins that contribute to inflammation and can cause itching and flaking.

Overall, Zinc Pyrithione (Antidandruff) works by controlling the growth of yeast and bacteria on the scalp, reducing inflammation, and promoting a healthier scalp environment.
This helps to reduce the symptoms of dandruff and other scalp conditions and improve the overall appearance and health of the hair and scalp.



TREAT DANDRUFF, ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff), coal tar, salicylic acid… the list goes on.
There are so many ways to treat dandruff – but what makes Zinc Pyrithione (Antidandruff) the world’s number one anti-dandruff ingredient?¹

Dandruff treatment can take one of two approaches:

*treat the symptoms – this is designed to address the visible symptoms like flakes or inflammation.
However, theunderlying cause of dandruff is still working away.


*tackle the cause – here you get to the root of the problem.
By tackling the cause you can achieve more completerelief and prevent the symptoms from reappearing, so it’s a good long-term solution.
Meet the products that just treat the symptoms of dandruff

Those dandruff treatments that merely work on the symptoms include coal tar and salicylic acid.
Coal tar helps to control the skin’s reaction to scalp irritants formed as the microbe Malassezia globosa breaks down naturaloils on the scalp.
So while you might not experience quite as much irritation, those substances are still being produced at the same rate... and could still damage your scalp.

Salicylic acid acts on the actual flakes.
It is designed to help break the bonds between dead skin cells to make them easier to washoff.

But just like coal tar, salicylic acid doesn’t tackle the underlying cause of your itch, irritation, or flakes – so it’s lesseffective against dandruff.
In fact, in clinical testing these products are far less effective at treating flakes than 1% Zinc Pyrithione (Antidandruff) shampoos.

A better long-term solution?
Pyrithione zinc
Easily the best way to treat dandruff and keep it away for good is to use an anti-dandruff shampoo with an active ingredient that tackles the root cause of dandruff.

That’s where Zinc Pyrithione (Antidandruff) comes in.
Zinc Pyrithione (Antidandruff) both removes and helps prevent the formation of scalp irritants, to keep your scalphealthy and comfortable.

With smaller particles, the dandruff-fighting active can:
*give longer lasting protection – because it’s smaller, it goes deeper into the pores, so it doesn’t rinse out and continues to protect you against dandruff long after the shower

*clean better – the small particles help to create more lather as you wash your hair

*leave your hair and scalp healthier – the particles spread more easily across the scalp and stay there for longer, giving your scalp the protection it needs and allowing your hair to grow from a healthier base



ZINC PYRITHIONE (ANTIDANDRUFF) VS. SELENIUM SULFIDE:
Selenium sulfide is a topical antifungal treatment that slows the growth of yeast on the scalp or body.
It’s available in both prescription and OTC forms.
Like Zinc Pyrithione (Antidandruff), it’s also commonly found in antidandruff shampoos, and the two ingredients can complement each other.
Selenium sulfide is known to be a bit stronger and can be irritating if left on the scalp for too long.
It’s naturally a light orange color, so shampoos or skin care products containing selenium sulfide are usually a peachy hue.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE (ANTIDANDRUFF):
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N

Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)

Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Relative vapor density: No data available

Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C

Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70<5 micron; D100<12 micron
Boiling Point:253.8C at 760 mmHg

flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (<0.1 g/100 mL at 21 C)
Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless

Melting point/freezing point
Melting point/range: 267 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)

Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262

Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (<0.1 g/100 mL at 21 C)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262



FIRST AID MEASURES of ZINC PYRITHIONE (ANTIDANDRUFF):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE (ANTIDANDRUFF):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE (ANTIDANDRUFF):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE (ANTIDANDRUFF):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE (ANTIDANDRUFF):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE (ANTIDANDRUFF):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

ZINC PYRITHIONE (ZPT)
Zinc Pyrithione (ZPT) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Pyrithione (ZPT) is the active ingredient in several anti-dandruff shampoos.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn


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Zinc Pyrithione (ZPT) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.
UV light slowly breaks down Zinc Pyrithione (ZPT), providing years of protection even in direct sunlight.


Zinc Pyrithione (ZPT) is a fine beige granules.
Zinc Pyrithione (ZPT) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.


Although the exact mechanism of action remains to be fully elucidated, Zinc Pyrithione (ZPT) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.
In addition, Zinc Pyrithione (ZPT) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.


Zinc Pyrithione (ZPT) has been the top choice among anti-dandruff agents around the world for more than 30 years.
Zinc Pyrithione (ZPT)'s potent action against Pityrosporum Ovale, the primary culprit for dandruff, ensures healthy, dandruff-free hair.
Unlike other treatments, Zinc Pyrithione (ZPT) also keeps fungal infections at bay, resulting in a scalp that's not just visibly clean, but truly healthy.


Zinc Pyrithione (ZPT) is a chemical compound of zinc.
Zinc Pyrithione (ZPT) is used as an antifungal and antibacterial agent.
Zinc is a metallic element with the atomic number 30.


It is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc Pyrithione (ZPT) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Pyrithione (ZPT) is approved for over-the-counter topical use in the United States as a treatment for dandruff.
Zinc Pyrithione (ZPT) is the active ingredient in several anti-dandruff shampoos.


The effectiveness of Zinc Pyrithione (ZPT) is well-established, but as with many modern medicines that have evolved from time-tested remedies, the way the drug actually works is less clear.
If Zinc Pyrithione (ZPT) is used as a preservative in cosmetic and hygiene products the total proportion can be no more than 0,5 %.


Zinc Pyrithione (ZPT) has also started to be used as an active substance in boat hull paint.
Topical Zinc Pyrithione (ZPT) appears to be a safe and effective treatment for psoriasis.
An aerosol preparation of Zinc Pyrithione (ZPT) (0.25%) in a vehicle containing isopropyl myristate appears to be a safe and effective treatment for psoriasis.


Zinc Pyrithione (ZPT) was found to be negative in mutation tests in bacteria and Chinese hamster ovary cells.
Similarly, no chromosomal aberration was observed in human lymphocytes incubated in vitro in the presence of Zinc Pyrithione (ZPT) or in lymphocytes harvested from monkeys.


The mineralization of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-on (DCOI) and Zinc Pyrithione (ZPT) was examined in laboratory tests with marine coastal sediments.
Zinc Pyrithione (ZPT) has been used as a booster biocide in antifouling paints of ships.


For its environmental risk assessment, a direct analyzing technique of Zinc Pyrithione (ZPT) has been developed using HPLC-MS without transforming to other substances.
Zinc Pyrithione (ZPT) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Zinc Pyrithione (ZPT) works against the viability of bacteria and fungi.
Zinc Pyrithione (ZPT) also works against dandruff.
Zinc Pyrithione (ZPT) is a potent antifungal agent in a water suspension format.


Zinc Pyrithione (ZPT) can restrain and sterilize eight moulds, including black mold,aspergillus flavus, aspergillus versicolor,penicillium citrinum, paecilomium varioti bainier,trichoderma viride, chaetomium globasum and cladosporium herbarum; five bacteria, such as E.coli, staphylococcus aureus, bacillus subtilis,bacillus megaterium and pseudomonas fluorescence as well as two yeast fungi which are distillery yeast and bakers’ yeast.


Zinc Pyrithione (ZPT) is an effective inhibitor of microbe growth
including algal, fungal (molds & yeasts) and bacterial (gram-positive & gram-negative).
Zinc Pyrithione (ZPT) is a “coordination complex” of zinc and pyrithione.


Zinc Pyrithione (ZPT) is one of the active ingredients we use in our shampoos.
On the 4th March 2020, the Scientific Committee on Consumer Safety concluded that Zinc Pyrithione (ZPT) is safe when used as an anti-dandruff in rinse-off hair products in a concentration of maximum 1%.


Being subject to several safety evaluations, Zinc Pyrithione (ZPT) was previously found safe as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.
This came as a result of a safety dossier that was submitted by Cosmetics Europe to demonstrate the safety of Zinc Pyrithione (ZPT) as anti-dandruff in rinse-off hair products.



USES and APPLICATIONS of ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.
Zinc Pyrithione (ZPT) has long been used as anti-dandruff agent and widely used in various popular shampoos.
Zinc Pyrithione (ZPT) is supplied as a powder or as a 50% water suspension emulsion.


The fine particle size of Zinc Pyrithione (ZPT) can effectively prevent precipitation and double the antimicrobial effect.
Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging, control white hair and hair loss generation.


Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus,playing a role in dandruff .
In the pesticide field, Zinc Pyrithione (ZPT) is used mainly to control apple leaf curl and scab, among others.


Zinc Pyrithione (ZPT) is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.
Zinc Pyrithione (ZPT) is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione (ZPT) is widely used as a fungicide for paints and plastics.


Zinc Pyrithione (ZPT) has unique advantages in environmental friendliness and sterilization persistence.
Therefore, Zinc Pyrithione (ZPT) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione (ZPT) is suitable for outdoor coatings and other products that protect against mold and algae.


In addition, Zinc Pyrithione (ZPT) is an effective algaecide.
Zinc Pyrithione (ZPT) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
As an anti-mildew agent, Zinc Pyrithione (ZPT) also has some applications on fabrics.


Therefore, Zinc Pyrithione (ZPT) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.
The optimum process conditions were determined by single-factor and orthogonal tests.


The process parameters of cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Pyrithione (ZPT) anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione (ZPT) is used as an additive to protect paints (such as industrial and marine) against microbe
(algal, fungal and bacterial) and crustacean growth.


Zinc Pyrithione (ZPT) acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.
Zinc Pyrithione (ZPT) can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.


For shampoo to remove dandruff, Zinc Pyrithione (ZPT) can inhibit the growth of gram-positive and negative bacteria and mold.
Zinc Pyrithione (ZPT) can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
In addition, Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil agent, and paint biocide.


As a fungicide for products such as coatings and plastics, Zinc Pyrithione (ZPT) is also widely used.
Anti-dandruff agent uses of Zinc Pyrithione (ZPT): Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)
Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Pyrithione (ZPT): Skin care (creams & lotions), Foot creams and Talcs


Rinse-off body wash products uses of Zinc Pyrithione (ZPT): Bar Soaps, Body wash, Bubble bath
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


Zinc Pyrithione (ZPT) also known as pyrithione zinc, pyrithionium zinc, olmaitin zinc, this zinc complex as early as in the 1930s was synthesized and used as an external antifungal agent or antibacterial agent.
Zinc Pyrithione (ZPT) is white to yellow crystalline powder at room temperature.


Zinc Pyrithione (ZPT) is slight characteristic odor.
Zinc Pyrithione (ZPT) is insoluble in water.
Zinc pyrazide forms insoluble deposits with cationic and non-ionic surfactants and is unstable to light and oxidants, and to acids and bases at higher temperatures.


Zinc Pyrithione (ZPT) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.
Although the exact mechanism of action remains to be fully elucidated, Zinc Pyrithione (ZPT) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.


In addition, Zinc Pyrithione (ZPT) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.
Zinc Pyrithione (ZPT) is used antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.


Zinc Pyrithione (ZPT) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Pyrithione (ZPT) products have been providing dandruff relief and improved scalp health for over 50 years.


Zinc Pyrithione (ZPT) is thus used in dandruff shampoos and also in various cosmetics and products against various skin problems.
Zinc Pyrithione (ZPT) is used as an antifungal and antibacterial agent.
Zinc Pyrithione (ZPT) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


Zinc Pyrithione (ZPT) can inhibit the growth of yeast, which is a main factor in dandruff.
As the name suggests, Zinc Pyrithione (ZPT) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.
Zinc Pyrithione (ZPT) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.


Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.


Zinc Pyrithione (ZPT)’s an ingredient in skincare and hair products because of its antibacterial, antimicrobial, and antifungal properties.
Zinc Pyrithione (ZPT) helps prevent the dandruff-causing microbe, Malassezia globosa, from making the substances that irritate your scalp.
The cosmetic ingredient Zinc Pyrithione (ZPT) is frequently used in the formulation of hair conditioners, shampoos, face powders, cleansing products, eyeliners and skin care products.


Zinc Pyrithione (ZPT) is currently regulated as a preservative in rinse-off products (with the exception of oral hygiene products) in a concentration of up to 0.5% in general products and up to 1.0% in hair products.
Moreover, Zinc Pyrithione (ZPT) is also allowed in a concentration up to 0.1% in leave-on hair products.


Zinc Pyrithione (ZPT) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione (ZPT) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.
Zinc Pyrithione (ZPT) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.


Zinc Pyrithione (ZPT) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione (ZPT) is very effective against a wide variety of pathogenic bacteria/fungus.
Sponges: Zinc Pyrithione (ZPT) is an antibacterial treatment for household sponges, as used by the 3M Corporation.


Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
In the cosmetic industry, zinc and zinc salts are used in various products.


Zinc Pyrithione (ZPT) is one of the zinc salts frequently used in hair conditioners, shampoos, face powders, cleaning products, eye pencils, cleaning and skin care products.
It is active against the bacteria E. coli, Zinc Pyrithione (ZPT) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.


Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.
Zinc Pyrithione (ZPT) is used Shampoo for dandruff.
Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.


Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is a preservative against bacteria, fungi, and yeast.


Zinc Pyrithione (ZPT) is unstable in light and in the presence of oxidizing agents.
Zinc Pyrithione (ZPT) is useful in gels, creams, heavy lotions, and talcum powder.
Zinc Pyrithione (ZPT) is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.


Zinc Pyrithione (ZPT) is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.
In recent years, there have been some regulatory updates concerning the use of Zinc Pyrithione (ZPT) in personal care and cosmetic products in Asia and globally.


Zinc Pyrithione (ZPT) is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Additionally, Zinc Pyrithione (ZPT) aids in controlling sebum production, contributing to a healthier scalp environment.


The chemical formula of Zinc Pyrithione (ZPT) is C10H8N2O2S2Zn.
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
Zinc Pyrithione (ZPT) with a high concentration of 48%.


Zinc Pyrithione (ZPT) is a biocide that effectively inhibits the growth of fungi and bacteria, making it a popular ingredient in anti-dandruff shampoos and scalp treatments.
Zinc Pyrithione (ZPT) is known for its ability to control and prevent dandruff and other scalp conditions caused by the overgrowth of certain microorganisms.


Additionally, Zinc Pyrithione (ZPT) can be found in skincare products to address other skin conditions like acne and seborrheic dermatitis due to its antimicrobial properties.
Zinc Pyrithione (ZPT) can stop yeast from growing, which is a major contributor to dandruff.


Zinc Pyrithione (ZPT), as its name implies, is a chemical compound made from zinc and is utilized in a number of hair and skin care products.
Zinc Pyrithione (ZPT), also known as pyrithione zinc, has antibacterial, antimicrobial, and antifungal qualities that can help cure acne, scalp psoriasis, and seborrheic dermatitis (also known as dandruff).


Zinc Pyrithione (ZPT) is anticipated to be ingested in significant quantities during the production of grooming items such soap and shower products, disinfectants, and antiseptic products.
As a result, Zinc Pyrithione (ZPT)'s consumption is predicted to increase at a significant rate, expanding the market size.


-Medicine uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione (ZPT):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (ZPT) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione (ZPT) is an algaecide.

Zinc Pyrithione (ZPT) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione (ZPT) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione (ZPT) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.


-Clothing uses of Zinc Pyrithione (ZPT):
A process to apply Zinc Pyrithione (ZPT) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (ZPT) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (ZPT) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Shampoo uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) shampoo is found in many common anti-dandruff shampoos.
Zinc Pyrithione (ZPT) is antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Cream uses of Zinc Pyrithione (ZPT):
Seborrheic dermatitis often affects the scalp, but Zinc Pyrithione (ZPT) can also cause rough, scaly patches on the skin.
Zinc Pyrithione (ZPT) cream is used to treat seborrheic dermatitis or psoriasis on the body.
For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione (ZPT) followed by a moisturizer.
You can also use the cream daily by applying it in a thin layer to the affected area.


-Face wash uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione (ZPT) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione (ZPT) may help clear acne.



ADVANTAGES OF ZINC PYRITHIONE (ZPT):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Zinc Pyrithione (ZPT) helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Zinc Pyrithione (ZPT) is used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



STRUCTURE OF ZINC PYRITHIONE (ZPT):
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via scission of one Zn-O bond.
Zinc Pyrithione (ZPT) was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



ZINC PYRITHIONE (ZPT) THE WORLD'S NUMBER ONE ANTI-DANDRUFF INGREDIENT?
Zinc Pyrithione (ZPT), coal tar, salicylic acid… the list goes on.
There are so many ways to treat dandruff – but what makes Zinc

Dandruff treatment can take one of two approaches:
*treat the symptoms – this is designed to address the visible symptoms like flakes or inflammation.
However, theunderlying cause of dandruff is still working away.

*tackle the cause – here you get to the root of the problem.
By tackling the cause you can achieve more completerelief and prevent the symptoms from reappearing, so it’s a good long-term solution.
Meet the products that just treat the symptoms of dandruff

Those dandruff treatments that merely work on the symptoms include coal tar and salicylic acid.
Coal tar helps to control the skin’s reaction to scalp irritants formed as the microbe Malassezia globosa breaks down naturaloils on the scalp.
So while you might not experience quite as much irritation, those substances are still being produced at the same rate... and could still damage your scalp.
Salicylic acid acts on the actual flakes.

It is designed to help break the bonds between dead skin cells to make them easier to washoff.
But just like coal tar, salicylic acid doesn’t tackle the underlying cause of your itch, irritation, or flakes – so it’s lesseffective against dandruff.
In fact, in clinical testing these products are far less effective at treating flakes than 1% Zinc Pyrithione (ZPT) shampoos.



ALTERNATIVES OF ZINC PYRITHIONE (ZPT):
*KETOCONAZOLE,
*SELENIUM SULFIDE



WHAT IS ZINC PYRITHIONE (ZPT) USED FOR?
Zinc Pyrithione (ZPT) is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, Zinc Pyrithione (ZPT) effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Pyrithione (ZPT) also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Pyrithione (ZPT)’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



ORIGIN OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is synthesized through a multistep chemical process. Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Pyrithione (ZPT) undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Pyrithione (ZPT) is then filtered, washed, and dried to obtain a fine powder.



WHAT DOES ZINC PYRITHIONE (ZPT) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



SHAMPOO ZINC PYRITHIONE (ZPT) MARKET: OVERVIEW
Zinc Pyrithione (ZPT), also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by Zinc Pyrithione (ZPT).
Zinc Pyrithione (ZPT), as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Pyrithione (ZPT) shampoo.
Zinc Pyrithione (ZPT) is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



ZINC PYRITHIONE (ZPT), A BETTER LONG-TERM SOLUTION?
Zinc Pyrithione (ZPT) is used easily the best way to treat dandruff and keep it away for good is to use an anti-dandruff shampoo with an activeingredient that tackles the root cause of dandruff.

That’s where Zinc Pyrithione (ZPT) comes in.
Zinc Pyrithione (ZPT) both removes and helps prevent the formation of scalp irritants, to keep your scalphealthy and comfortable.

With smaller particles, the dandruff-fighting active can:
*give longer lasting protection – because it’s smaller, Zinc Pyrithione (ZPT) goes deeper into the pores, so it doesn’t rinse out and continues to protect you against dandruff long after the shower

*clean better – the small particles help to create more lather as you wash your hair

*leave your hair and scalp healthier – the particles spread more easily across the scalp and stay there for longer, giving your scalp the protection Zinc Pyrithione (ZPT) needs and allowing your hair to grow from a healthier base



PROPERTIES OF ZINC PYRITHIONE (ZPT):
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



FUNCTIONS OF ZINC PYRITHIONE (ZPT):
*To combat dandruff,
*To control sebum production,
*Zinc Pyrithione (ZPT) helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Pyrithione (ZPT) prevents the development of microorganisms in cosmetic products.
*According to the SCCS (Scientific Committee on Consumer Safety) opinion published in 2014 and 2018, Zinc Pyrithione (ZPT) was found safe to use as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.



WHERE IS ZINC PYRITHIONE (ZPT) FOUND?
Zinc Pyrithione (ZPT) is an antibacterial and antifungal agent.
Zinc Pyrithione (ZPT) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Pyrithione (ZPT) is an antibacterial and antifungal agent.
Zinc Pyrithione (ZPT) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Pyrithione (ZPT) is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Pyrithione (ZPT) products have been providing dandruff relief and improved scalp health for over 50 years.



FUNCTIONS AND PROPERTIES OF ZINC PYRITHIONE (ZPT):
*Mechanism of Pyrithione-Induced Membrane
*Depolarization in Neurospora crassa
*A clinically controled prospective study with histology
*Embryotoxicity of the antifouling biocide zinc pyrithione to sea urchin (Paracentrotus lividus) and mussel (Mytilus edulis)



SHAMPOO ZINC PYRITHIONE (ZPT) MARKET: OVERVIEW
The demand for Zinc Pyrithione (ZPT) from the intended end use industries is anticipated to drive market expansion.
One of the main factors influencing Zinc Pyrithione (ZPT)'s growth is the usage of antibacterial coating in numerous applications, including the food and beverage, textile, and paint and coating sectors for anti-bacterial activity.
A further important element that has been thought to propel the growth of the worldwide Zinc Pyrithione (ZPT) market is the expansion and increased demand for personal care products.



MECHANISM OF ACTION OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



PREPARATION OF ZINC PYRITHIONE (ZPT):
Method 1:
The principle of preparation is that ZnSO4·7H2O reacts with SPT to produce Zinc Pyrithione (ZPT) and sodium sulfate.
Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.
The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain Zinc Pyrithione (ZPT) crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Pyrithione (ZPT) powder.

Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.

Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.

Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Pyrithione (ZPT) with a yield of about 75%.



BACTERICIDAL MECHANISM OF ZINC PYRITHIONE (ZPT):
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Pyrithione (ZPT) varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Pyrithione (ZPT) is not the same as that of many bactericides, as it kills bacteria without being consumed.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE (ZPT):
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0

Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available

Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available

Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų

Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314

HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.



FIRST AID MEASURES of ZINC PYRITHIONE (ZPT):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE (ZPT):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE (ZPT):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE (ZPT):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE (ZPT):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE (ZPT):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC PYRITHIONE (ZPT)
Zinc Pyrithione (ZPT) is slight characteristic odor.
Zinc Pyrithione (ZPT) is insoluble in water.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chem/IUPAC Name: Pyridine-2-thiol-1-oxide, zinc complex (2:1)
Chemical formula: C10H8N2O2S2Zn



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Zinc Pyrithione (ZPT) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.


It is active against the bacteria E. coli, Zinc Pyrithione (ZPT) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.
Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.


Zinc Pyrithione (ZPT) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (ZPT) is known for its ability to fight dandruff and promote a healthy scalp.
Zinc Pyrithione (ZPT) is a chemical compound consiting of zinc and pyrithione.


Zinc Pyrithione (ZPT) is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.
Zinc Pyrithione (ZPT) is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent.


At room temperature Zinc Pyrithione (ZPT) is white to yellow crystalline powder.
Zinc Pyrithione (ZPT), also known as Pyrithione Zinc, is an antibacterial, antimicrobial, and antifungal agent that can be used to treat dandruff, scalp psoriasis, and acne.


Zinc Pyrithione (ZPT) is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dimer.
Zinc Pyrithione (ZPT) is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.


Zinc Pyrithione (ZPT)offers bactericide-fungicide efficacy.
Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (ZPT)acts as an anti-dandruff and odor-controlling agent.


Zinc Pyrithione (ZPT)offers bactericide-fungicide efficacy.
Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (ZPT)inhibits the growth of a broad spectrum of both Gram-positive and Gram-negative bacteria.


Zinc Pyrithione (ZPT) is slight characteristic odor.
Zinc Pyrithione (ZPT) is insoluble in water.
Zinc Pyrithione (ZPT) is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.


Zinc Pyrithione (ZPT) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.
Due to low solubility, Zinc Pyrithione (ZPT) released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.


Other uses of Zinc Pyrithione (ZPT) include additive in antifouling outdoor paints and algaecide. While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione (ZPT) has been reported for decades.
Zinc Pyrithione (ZPT)also inhibits the growth of fungi, yeast, mold, and algae.


Zinc Pyrithione (ZPT)is a mixture of ultra-fine particles of zinc pyrithione (ZPT), a dispersant and a stabilizing agent.
Zinc Pyrithione (ZPT)is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and
bacterial (gram-positive & gram-negative).


Zinc Pyrithione (ZPT)is a fungistatic and baceriostatic compound that has a variety of uses.
Zinc Pyrithione (ZPT) has the ability to inhibit the growth of yeast, which is a major cause of dandruff.
If you're struggling with dandruff or other scalp issues, look for hair care products containing Zinc Pyrithione (ZPT) to help alleviate your symptoms and promote a healthy scalp.


Zinc Pyrithione (ZPT) has long been used as anti-dandruff agent and widely used in various popular shampoos.
Zinc Pyrithione (ZPT) is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Pyrithione (ZPT) can effectively prevent precipitation and double the antimicrobial effect.


Zinc Pyrithione (ZPT) is a chemical compound derived from the natural element Zinc.
Zinc Pyrithione (ZPT) was first developed in the 1930s, then synthesized by E. Shaw in 1950.
So while it does draw from the naturally occurring metal, Zinc Pyrithione (ZPT) is ultimately produced in a lab.


Zinc Pyrithione (ZPT) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione (ZPT) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.
Zinc Pyrithione (ZPT) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione (ZPT) works by targeting both local fungi and bacteria residing on the scalp.
This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.


For instance, Zinc Pyrithione (ZPT)’s an essential element in kitchen sponges, preventing the growth of mould.
Zinc Pyrithione (ZPT) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (ZPT) is known for its ability to fight dandruff and promote a healthy scalp.


Additionally, Zinc Pyrithione (ZPT) aids in controlling sebum production, contributing to a healthier scalp environment.
The chemical formula of Zinc Pyrithione (ZPT) is C10H8N2O2S2Zn.
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.



USES and APPLICATIONS of ZINC PYRITHIONE (ZPT):
Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione (ZPT) is suitable for outdoor coatings and other products that protect against mold and algae.
In addition, Zinc Pyrithione (ZPT) is an effective algaecide.


Zinc Pyrithione (ZPT)is used in skincare, shampoos, conditioners and leave-on products.
Zinc Pyrithione (ZPT)is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Zinc Pyrithione (ZPT) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
As an anti-mildew agent, Zinc Pyrithione (ZPT) also has some applications on fabrics.
Therefore, Zinc Pyrithione (ZPT) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


The optimum process conditions were determined by single-factor and orthogonal tests.
The process parameters of cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Pyrithione (ZPT)is used as an additive to protect paints (such as industrial and marine) against
microbe (algal, fungal and bacterial) and crustacean growth.
Zinc Pyrithione (ZPT)acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.


Zinc Pyrithione (ZPT)can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.
Zinc Pyrithione (ZPT)is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Pyrithione (ZPT) anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione (ZPT) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.


As the name implies, Zinc Pyrithione (ZPT) is generated from the chemical element zinc and is utilized in several haircare and skincare products.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione (ZPT) is used to treat dandruff and seborrheic dermatitis.
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione (ZPT) works by targeting both local fungi and bacteria residing on the scalp.
This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.


Zinc Pyrithione (ZPT)is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione (ZPT)is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.


Zinc Pyrithione (ZPT)is a highly effective bactericide-fungicide, the anti-dandruff agent establishes the market standard for any active ingredient solutions in anti-dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion's high antimicrobial efficacy combined with the acceptability for human use has made it the agent of choice for anti-dandruff shampoo manufacturers worldwide.


In addition, an important characteristic of this molecule is that Zinc Pyrithione (ZPT)is efficacious against various bacteria species associated with producing odor on the skin.
Zinc Pyrithione (ZPT)is a fungistatic and bacteriostatic compound that has a variety of uses.


Zinc Pyrithione (ZPT)is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).
Zinc Pyrithione (ZPT)is also often used in kitchen sponges as an antibacterial treatment.


UV light slowly breaks down Zinc Pyrithione (ZPT), providing years of protection even in direct sunlight.
In the pesticide field, Zinc Pyrithione (ZPT) is used mainly to control apple leaf curl and scab, among others.
Zinc Pyrithione (ZPT) is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.


Zinc Pyrithione (ZPT) is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione (ZPT) is widely used as a fungicide for paints and plastics.
Zinc Pyrithione (ZPT) has unique advantages in environmental friendliness and sterilization persistence.


Therefore, Zinc Pyrithione (ZPT) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Zinc Pyrithione (ZPT) can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.
As the name suggests, Zinc Pyrithione (ZPT) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.


Pharmaceutical Applications of Zinc Pyrithione (ZPT): Zinc Pyrithione (ZPT) is a regulator of keratinization, has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).
Zinc Pyrithione (ZPT) has a strong killing effect on fungi and bacteria, can effectively kill the fungus that produces dandruff, and has an anti-dandruff effect.


Zinc Pyrithione (ZPT) is used as a bactericide for coatings and plastics, etc.
Zinc Pyrithione (ZPT) is used in shampoos to remove dandruff, and can inhibit the growth of Gram-positive and negative bacteria and molds.
Zinc Pyrithione (ZPT) can effectively care for the hair, delay the aging of the hair, and control the generation of gray hair and hair loss.


Zinc Pyrithione (ZPT) has strong killing power on fungi and bacteria, can effectively kill the fungi that produce dandruff, and play an anti-dandruff effect.
Zinc Pyrithione (ZPT), as an anti-dandruff agent with a long history, is widely known in the shampoo industry and used by many well-known brands.


In addition, Zinc Pyrithione (ZPT) is used in paint to prevent fouling and plugging.
This paint is harmless to the human body and the sea water environment, has a good anti-fouling effect on the organism, and can effectively prevent the sea The equipment is fouled.


In addition, Zinc Pyrithione (ZPT) can be used to treat peeling, such as psoriasis, dermatitis and similar skin diseases.
Zinc Pyrithione (ZPT) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.


Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.
For shampoo to remove dandruff, Zinc Pyrithione (ZPT) can inhibit the growth of gram-positive and negative bacteria and mold.


Zinc Pyrithione (ZPT) can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
In addition, Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil agent, and paint biocide.
Zinc Pyrithione (ZPT) is used as a fungicide for products such as coatings and plastics, it is also widely used.


Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging,control white hair and hair loss generation.
Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, and paint biocide.


Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus, playing a role in dandruff .
Zinc Pyrithione (ZPT) is used Shampoo for dandruff.
Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively , delay hair aging ,control white hair and hair loss generation.


Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is used as anti-dandruff agent and bactericide in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.


Zinc Pyrithione (ZPT) is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Anti-dandruff agent uses of Zinc Pyrithione (ZPT): Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)
Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Pyrithione (ZPT): Skin care (creams & lotions), Foot creams and Talcs


Rinse-off body wash products uses of Zinc Pyrithione (ZPT): Bar Soaps, Body wash, Bubble bath
Zinc Pyrithione (ZPT) is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.
Zinc Pyrithione (ZPT) is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.


In recent years, there have been some regulatory updates concerning the use of Zinc Pyrithione (ZPT) in personal care and cosmetic products in Asia and globally.
Zinc Pyrithione (ZPT) is active against the bacteria E. coli, Zinc pyrithione reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.


Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.
Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.


Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.
Zinc Pyrithione (ZPT) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.


Zinc Pyrithione (ZPT) is very effective against a wide variety of pathogenic bacteria/fungus.
Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
Sponges: Zinc Pyrithione (ZPT) is an antibacterial treatment for household sponges, as used by the 3M Corporation.


-Zinc pyrithione shampoo:
Zinc Pyrithione (ZPT) shampoo is found in many common anti-dandruff shampoos.
Zinc Pyrithione (ZPT) is antifungal, antibacterial, and antimicrobialTrusted Source, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Zinc Pyrithione (ZPT) cream:
Seborrheic dermatitis often affects the scalp, but it can also cause rough, scaly patches on the skin.
Zinc Pyrithione (ZPT) cream is used to treat seborrheic dermatitis or psoriasisTrusted Source on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione (ZPT) followed by a moisturizer.
You can also use the cream daily by applying Zinc Pyrithione (ZPT) in a thin layer to the affected area.


-Clothing uses of Zinc Pyrithione (ZPT):
A process to apply Zinc Pyrithione (ZPT) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (ZPT) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (ZPT) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Zinc pyrithione face wash:
Zinc Pyrithione (ZPT) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione (ZPT) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione (ZPT) may help clear acne.


-Medicine uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione (ZPT):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (ZPT) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione (ZPT) is an algaecide.

Zinc Pyrithione (ZPT) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione (ZPT) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione (ZPT) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges: Zinc Pyrithione (ZPT) is an antibacterial treatment for household sponges, as used by the 3M Corporation.
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


-Clothing uses of Zinc Pyrithione (ZPT):
A process to apply Zinc Pyrithione (ZPT) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (ZPT) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (ZPT) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Medicine uses of Zinc Pyrithione (ZPT):
Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione (ZPT):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (ZPT) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione (ZPT) is an algaecide.

Zinc Pyrithione (ZPT) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione (ZPT) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione (ZPT) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.



WHAT IS ZINC PYRITHIONE (ZPT) USED FOR?
Zinc Pyrithione (ZPT) is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, this ingredient effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Pyrithione (ZPT) also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Pyrithione (ZPT)’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



HOW TO USE ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is easily found in many drugstore and supermarket shampoo products.
There are also leave-in treatments available from retail haircare lines.
Depending on the severity of your condition, your dermatologist may recommend a stronger treatment that may need a prescription.


*Use in an anti-dandruff shampoo:
Zinc Pyrithione (ZPT) is most often found in anti-dandruff shampoos.
For best results, you should wet your hair and massage the shampoo into your scalp.

Let Zinc Pyrithione (ZPT) sit for approximately one minute (or as instructed on the shampoo label) before shampooing the rest of your hair and then rinse out.

Usage will depend on the sensitivity and state of your scalp.
While many shampoos containing Zinc Pyrithione (ZPT) can be used daily, I typically recommend using it at least two to three times per week.
For some individuals dealing with seborrheic dermatitis or dandruff,

I often recommend washing the scalp daily or every other day to help eliminate the build-up of oils or dead skin, which may contribute to scaling or flaking.
If someone is concerned about dryness of the scalp, it is okay to use a Zinc Pyrithione (ZPT) shampoo a few days per week and a non-medicated shampoo on the alternating days.


*Use in a hydrating conditioner:
Conditioners with Zinc Pyrithione (ZPT) can help fight dandruff, itch, and flaking while restoring scalp balance and providing hydration.
After shampooing, massage the conditioner into your scalp and hair and cover Zinc Pyrithione (ZPT) with a shower cap.
Leave on for 3 minutes and wash out.
Follow the instructions on the label for the best results.


*Relieve itch and flakes with a serum:
Serums with Zinc Pyrithione (ZPT) are great for those with oily scalps or severe flaking and dandruff.
Apply the serum to the scalp in between washes to help with itch and flakes.
Follow the directions on the product, but most can be applied several times a day.


*Apply in a scalp-soothing leave-in cream:
If your scalp tends to get dry, a leave-in cream is often more soothing and moisturizing than a serum.
The creams are often infused with hydrating products like vitamin E and argan oil to protect and moisturize, while the Zinc Pyrithione (ZPT) relieves dandruff, itch, and irritation.



APPEARANCE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is a milky white suspension
Zinc Pyrithione (ZPT)is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.



FUNCTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is best known for its use in treating dandruff and seborrhoeic dermatitis.



KEY PRODUCT ATTRIBUTES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
– Relieves flaking symptoms of dandruff
– Targets scalp with a slow release for highest efficacy
– Effective dispersion because it is not soluble
– Enhances substantivity to the skin and hair
– Maintains efficacy over long-term use without resistance



GENERAL PROPERTIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)Antimicrobial:
– Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent
– Zinc Pyrithione (ZPT)inhibits the growth of a broad spectrum of both Gram positive and Gram negative bacteria
– Zinc Pyrithione (ZPT)inhibits the growth of fungi, both yeast and mold
– Zinc Pyrithione (ZPT)inhibits the growth of algae



KEY PRODUCT ATTRIBUTES FOR ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)relieves flaking symptoms of dandruff
Zinc Pyrithione (ZPT)targets scalp with a slow release for highest efficacy
Effective dispersion because Zinc Pyrithione (ZPT)is not soluble
Zinc Pyrithione (ZPT)enhances substantivity to the skin and hair
Zinc Pyrithione (ZPT)maintains efficacy over long-term use without resistance



STRUCTURE OF ZINC PYRITHIONE (ZPT):
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Zinc Pyrithione (ZPT) was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



MECHANISM OF ACTION OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



FUNCTIONS OF ZINC PYRITHIONE (ZPT) ARE:
*To combat dandruff,
*To control sebum production,
*Zinc Pyrithione (ZPT) helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Pyrithione (ZPT)prevents the development of microorganisms in cosmetic products.



GENERAL PROPERTIES AND APPLICATIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (ZPT)is an effective antidandruff agent.
Zinc Pyrithione (ZPT)is the growth of a broad spectrum of both Gram positive and Gram negative bacteria.
Zinc Pyrithione (ZPT)inhibits the growth of fungi, both yeast and mold.
Zinc Pyrithione (ZPT)inhibits the growth of algae.



CHEMICAL INCOMPATIBILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Transchelation occurs in the presence of heavy metal ions.
Even traces of the corresponding chelates can cause a noticeable discoloration, foremost the iron and copper complexes.
Zinc Pyrithione (ZPT)is sensitive to strong oxidizing and reducing agents.

The Conductivity of water should be less than 5μs/cm Calculate the dosage to ensure that whole barrels of product would be added for each batch.
It is recommended to add a little zinc salt to the water to ovoid occurring Fe(III) complexes when the conductivity of the water is less than 20μs/cm.
Zinc Pyrithione (ZPT)is incompatible with EDTA, which, however, does no harm the sterilizing effect of Zinc pyrithione



STABILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)remains stable for 120 hours at 100℃, decomposes at 240℃。
Zinc Pyrithione (ZPT)is sensitive to light and remains stable in pigmented coatings.
Zinc Pyrithione (ZPT)is hydrolytically stable between pH 4.5 and 9.5.
Below pH 4.5 conversion to pyrithione occurs.
In alkaline solutions (pH > 9.5) conversion to soluble alkali salts occurs.



PRECAUTIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Stores Zinc Pyrithione (ZPT)in original container in a dry and cool area away from direct sunlight with temperature between 10℃ and 54℃.
Keep the Zinc Pyrithione (ZPT)container tightly closed and sealed until ready for use.

Containers opened must be carefully resealed and kept upright to prevent leakage.
Agitate the barrels every 6 weeks.
Pre-agitate for at least 10 minutes before using.

May be pre-dispersed by a certain amount of water to assure better dispersion.
Calculate the dosage to ensure that whole barrels of the product are added for each batch.



PRODUCT BACKGROUND OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.



BENEFITS OF ZINC PYRITHIONE (ZPT) FOR HAIR:
Zinc Pyrithione (ZPT) is an active ingredient commonly used in anti-dandruff shampoos and personal care products to treat scalp conditions such as seborrheic dermatitis and psoriasis.
Zinc Pyrithione (ZPT) is a coordination complex of zinc that contains pyrithione, a biocide with antibacterial and antifungal properties.

Zinc Pyrithione (ZPT) works by slowing down the growth of skin cells and reducing the production of yeast, which is a major contributor to dandruff and other scalp conditions.

Zinc Pyrithione (ZPT) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
In addition to its use in personal care products, Zinc Pyrithione (ZPT) is also used as an industrial biocide to control the growth of algae and other microorganisms in water-based systems such as paints, coatings, and adhesives.



HOW DOES ZINC PYRITHIONE (ZPT) WORK?
Zinc Pyrithione (ZPT) works by targeting the fungus Malassezia, which is a common cause of dandruff and other scalp conditions.
Malassezia is a type of yeast that naturally lives on the scalp and feeds on oils secreted by the hair follicles.

Zinc Pyrithione (ZPT) works by disrupting the cell membranes of Malassezia, causing it to die off and reducing its ability to reproduce.
In addition to its antifungal properties, Zinc Pyrithione (ZPT) also has antibacterial properties that help to eliminate the bacteria that can contribute to scalp odour.

Zinc Pyrithione (ZPT) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
Zinc Pyrithione (ZPT) works by inhibiting the production of cytokines, which are proteins that contribute to inflammation and can cause itching and flaking.

Overall, Zinc Pyrithione (ZPT) works by controlling the growth of yeast and bacteria on the scalp, reducing inflammation, and promoting a healthier scalp environment.
This helps to reduce the symptoms of dandruff and other scalp conditions and improve the overall appearance and health of the hair and scalp.



ACTIVITIES OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
It is active against the bacteria E. coli, Zinc Pyrithione (ZPT) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.

Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.
Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively, delay hair aging, control white hair and hair loss generation.
Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.

Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione (ZPT) is very effective against a wide variety of pathogenic bacteria/fungus.



MECHANISM OF ACTION OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



WHERE IS ZINC PYRITHIONE (ZPT) FOUND?
Zinc Pyrithione (ZPT) is an antibacterial and antifungal agent.
Zinc Pyrithione (ZPT) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.



BENEFITS AND USES OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is highly effective, keeping in mind that it is gentle and mild on the skin.
Many anti-dandruff shampoos contain Zinc Pyrithione (ZPT).

Zinc Pyrithione (ZPT) is antifungal, antibacterial, and antimicrobial, which means it can fight fungus, bacteria, and germs that cause itchy, flaky skin on the scalp.

Zinc Pyrithione (ZPT) cream is used to treat psoriasis and seborrheic dermatitis also called dandruff.
Face washes containing Zinc Pyrithione (ZPT) can help relieve the redness and irritation caused by seborrheic dermatitis on the face.
Zinc Pyrithione (ZPT) can also assist with the greasiness that comes with eczema and seborrheic dermatitis.



WHAT IS ZINC PYRITHIONE (ZPT), AND WHAT IS ZINC PYRITHIONE (ZPT) USED FOR?
Zinc Pyrithione (ZPT) is a chemical compound with antifungal and antimicrobial properties, used to treat seborrheic dermatitis and dandruff.
Seborrheic dermatitis is believed to result from an inflammatory skin reaction to the overgrowth of Malessezia yeast that commonly lives on the skin surface.

Seborrheic dermatitis causes redness, itching, and skin flaking, including dandruff on the scalp.
Zinc Pyrithione (ZPT) is also used off-label to treat tinea versicolor, another fungal skin infection.
Zinc Pyrithione (ZPT) is commonly used as the main active ingredient in anti-dandruff shampoos, conditioners, soaps, lotions, and creams available over the counter (OTC).

Zinc Pyrithione (ZPT) inhibits yeast growth by increasing the cellular levels of copper and damaging iron-sulfur clusters of proteins that are essential for fungal metabolism and growth.
Zinc Pyrithione (ZPT) has a broad spectrum of activity against organisms including fungi, and gram-positive and gram-negative bacteria.



ZINC AND ZINC PYRITHIONE:
Zinc is a trace mineral, vital to the human body and all forms of life, having catalytic, structural and regulatory functions.
Nevertheless, high levels of dietary zinc can cause anemia, decreased absorption levels of copper and iron, and reduction of enzyme activities in several tissues.
In 2003, the Scientific Committee on Food (SCF) established a tolerable total uptake level (UL) of Zinc up to 25 mg.

In the cosmetic industry, Zinc and zinc salts are used in a variety of categories.
Cosmetic products might account for maximum 10% of the UL.
One of the most widely used zinc salt is Zinc Pyrithione.

It is an aromatic Zinc Pyrithione (ZPT) used as an antidandruff, antiseborrhoeic, hair conditioning agent and preservative in cosmetics and personal care products.
Zinc Pyrithione (ZPT) has been used for more than 60 years as an anti-dandruff agent in concentration up to 1-2%.

In the European Union (EU), in accordance with the European Cosmetic Regulation No. 1223/2009,, Zinc Pyrithione (ZPT) is included in the list of substances which cosmetic products must not contain except subject to the restrictions laid down.
According to same Regulation, Zinc Pyrithione is also included in the Annex V (list of preservatives allowed in cosmetic products), and may be used as a preservative in rinse-off products (excluding oral hygiene products) in a concentration up to 1% in hair products and 0.5% in other products.

The U.S. Food and Drug Administration (FDA) allows the use of Zinc Pyrithione as an active ingredient in Over-The-Counter (OTC) dandruff and seborrheic dermatitis drug products.



WHAT IS ZINC PYRITHIONE (ZPT) USED FOR AND HOW DOES ZINC PYRITHIONE (ZPT) WORK?
Zinc Pyrithione (ZPT) is an over-the-counter (OTC) product used to treat dandruff (seborrhea).



HOW ZINC PYRITHIONE (ZPT) WORKS?
Zinc Pyrithione (ZPT) works by inhibiting the growth of yeast, which is the main factor in dandruff.
Zinc Pyrithione (ZPT) works by supplying moisture to the skin and scalp, thereby hydrating them.



CONCENTRATION AND SOLUBILITY OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is recommended that it be used at a concentration of 0.5 to 1% for best results.
Zinc Pyrithione (ZPT) is soluble in water and alcohol but insoluble in volatile oils.



HOW TO USE ZINC PYRITHIONE (ZPT):
Mix Zinc Pyrithione (ZPT) with water in the recommended concentration and stir until a homogeneous mixture is created.
Add other surfactants and enhancing ingredients like essential oils, depending on your product and need, and mix properly.
Add this mixture to the warm base of the product and stir until the desired thickness and texture are obtained.



ADVANTAGES OF ZINC PYRITHIONE (ZPT):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



ALTERNATIVES OF ZINC PYRITHIONE (ZPT):
*KETOCONAZOLE,
*SELENIUM SULFIDE



SAFETY PROFILE OF ZINC PYRITHIONE (ZPT):
While generally safe for topical use, Zinc Pyrithione (ZPT) may cause mild side effects such as skin irritation, redness, or dryness, especially in individuals with sensitive skin.
Prolonged or excessive use can exacerbate these symptoms.
Additionally, some people may experience allergic reactions characterized by itching or swelling.
Zinc Pyrithione (ZPT) is advisable to perform a patch test before widespread application and discontinue use if adverse reactions occur.



ORIGIN OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is synthesized through a multistep chemical process.
Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Pyrithione (ZPT) undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Pyrithione (ZPT) is then filtered, washed, and dried to obtain a fine powder.



WHAT DOES ZINC PYRITHIONE (ZPT) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



TYPE OF INGREDIENT OF ZINC PYRITHIONE (ZPT):
*Antifungal,
*antimicrobial,
*antibacterial properties



MAIN BENEFITS OF ZINC PYRITHIONE (ZPT):
Treats dandruff, soothes scalp irritation, regulates oil production, and prevents itching.



WHO SHOULD USE ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is best for those experiencing dandruff or seborrheic dermatitis, which may be associated with an oily scalp.
It is best to consult a dermatologist to determine the cause of your scalp flakes or irritation before using Zinc Pyrithione (ZPT).



HOW OFTEN CAN YOU USE ZINC PYRITHIONE (ZPT):
Shampoos containing Zinc Pyrithione (ZPT) can be used daily, and those individuals dealing with seborrheic dermatitis or dandruff are often advised to cleanse daily.
If the scalp is dry, it is okay to use a Zinc Pyrithione (ZPT) shampoo two to three days per week and a non-medicated shampoo on alternating days.



ZINC PYRITHIONE (ZPT) WORKS WELL WITH:
Selenium sulfide, another ingredient commonly found in dandruff shampoos stronger than Zinc Pyrithione (ZPT).
Additionally, some individuals may alternate with other Zinc Pyrithione (ZPT) ingredients, such as ketoconazole, an antifungal ingredient.



DON’T USE WITH:
There are no known ingredients that negatively interfere with Zinc Pyrithione (ZPT); however, it is advised that you speak to a medical professional before using if you are pregnant or nursing.



PREPARATION OF ZINC PYRITHIONE (ZPT):
Method 1:
The principle of preparation is that ZnSO4·7H2O reacts with SPT to produce Zinc Pyrithione (ZPT) and sodium sulfate.

Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.

The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain
Zinc Pyrithione (ZPT) crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Pyrithione (ZPT).


Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.


Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.


Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Pyrithione (ZPT) with a yield of about 75%.



WHAT HAIR TYPES CAN USE ZINC PYRITHIONE (ZPT)?
Experts agree that Zinc Pyrithione (ZPT) is safe for all hair types but would be most beneficial for those experiencing dandruff, seborrheic dermatitis, or other scalp conditions that are aggravated by fungus/yeast.

Some formulations of shampoos and topical scalp products include Zinc Pyrithione (ZPT) and hydrating and moisturizing ingredients that would be better for those with dry or color-treated hair.

If you don't have dandruff or other scalp conditions, skipping the products with Zinc Pyrithione (ZPT) is best.
The only downside is that Zinc Pyrithione (ZPT) could ultimately dry out the hair and scalp slightly and upset a healthier scalp microbiome if there is no dandruff or inflammation.

Zinc Pyrithione (ZPT) is always best to speak with a medical professional to evaluate the scalp and determine the best course of treatment.
For those with dry or sensitive skin, it is best to slowly incorporate Zinc Pyrithione (ZPT) into a routine and use caution as some dryness and irritation may occur, Garshick explains.
Engelman cautions that it is best to speak to a medical professional if you are pregnant or nursing before using Zinc Pyrithione (ZPT).



BENEFITS OF ZINC PYRITHIONE (ZPT) FOR HAIR:
The benefits of Zinc Pyrithione (ZPT) extend beyond the skin of the scalp.
By improving the health of the scalp, the health of the hair benefits as well.
Zinc Pyrithione (ZPT) has the power to treat a variety of issues, including dandruff, itchiness, acne, and scalp psoriasis by targeting the yeast/fungus that is causing the problem.


*Zinc Pyrithione (ZPT) fights dandruff-causing fungus:
The antifungal, antimicrobial, and antibacterial properties stop dandruff at its source.
Zinc Pyrithione (ZPT) is naturally anti-inflammatory and is also antifungal and antibacterial.
Since dandruff is caused directly by an excessive amount of fungus and yeast living on the scalp, by adding the Zinc Pyrithione (ZPT), you decrease the fungal buildup on the scalp and alleviate the inflammation causing the dandruff.


*Zinc Pyrithione (ZPT) prevents itching:
Dandruff is one of the leading causes of scalp itchiness.
By preventing dandruff and eliminating the irritating yeast/fungus that causes it, Zinc Pyrithione (ZPT) provides itch relief quickly.


*Zinc Pyrithione (ZPT) regulates oil production:
Zinc Pyrithione (ZPT) can control the oil production and dandruff often found in those with seborrheic dermatitis.


*Zinc Pyrithione (ZPT) improves overall scalp health:
Dandruff disrupts the health of the scalp by clogging follicles with flakes and by causing inflammation and irritation.
Zinc Pyrithione (ZPT) is able to improve the overall health of the scalp by preventing and treating dandruff.


*Zinc Pyrithione (ZPT) promotes hair growth:
Zinc Pyrithione (ZPT) has the potential to impact hair growth.
Since a number of thinning hair and hair loss concerns are related to the scalp, Zinc Pyrithione (ZPT) can help clear dead skin cells or conditions that prevent hair growth (clogged hair follicles, psoriasis, etc.) and thus promote fuller, healthier hair.
Garshick agrees and points out a study that showed that daily use of 1 percent Zinc Pyrithione (ZPT) shampoo over 26 weeks showed an improvement in hair growth.


*Zinc Pyrithione (ZPT) improves overall appearance of hair:
The overall appearance of the hair is heavily influenced by the oiliness of the scalp and the thickness of the hair.
By regulating oil production and encouraging new growth, Zinc Pyrithione (ZPT) can boost the overall appearance of the hair.



PROPERTIES OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is a clarifying shampoo for dry & dandruff-prone hair.
-Effectively cleanses & purifies hair.
Zinc Pyrithione (ZPT) helps eliminate itching & controls dandruff while visibly reducing flakes and leaves hair fresh & healthy-looking.

It contains Zinc Pyrithione (ZPT) – an active ingredient with antifungal and antibacterial properties, which intensely improves the scalp condition.
Zinc Pyrithione (ZPT) combats dandruff, seborrhoea and other undesirable changes.
In addition, bisabolol has antiseptic and anti-inflammatory properties, which soothe and restore comfort.



SHAMPOO ZINC PYRITHIONE (ZPT) MARKET: OVERVIEW
Zinc Pyrithione (ZPT), also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by it.

Zinc Pyrithione (ZPT), as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Pyrithione (ZPT) shampoo.
Zinc Pyrithione (ZPT) is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



PROPERTIES OF ZINC PYRITHIONE (ZPT):
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



BACTERICIDAL MECHANISM OF ZINC PYRITHIONE (ZPT):
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Pyrithione (ZPT) varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Pyrithione (ZPT) is not the same as that of many bactericides, as it kills bacteria without being consumed.



HOW TO USE ZINC PYRITHIONE (ZPT):
Apply Zinc Pyrithione (ZPT) to wet hair and massage in.
Rinse thoroughly.
If necessary, repeat the process.
Use Zinc Pyrithione (ZPT) daily or as special treatment.



ZINC PYRITHIONE (ZPT) IN TOPICAL TREATMENTS:
Zinc Pyrithione (ZPT) is an antifungal and antibacterial agent.
That’s what makes Zinc Pyrithione (ZPT) so powerful at fighting dandruff — more on that later.
Here are some of the highlights when it comes to using Zinc Pyrithione (ZPT) in topical treatments.

*Low Solubility:
A key element of Zinc Pyrithione (ZPT)’s power is that it has relatively low solubility, meaning it has staying power on our skin.
Zinc Pyrithione (ZPT) stays on our scalps, even after we’ve rinsed our hair of shampoo so that it can continue to fight fungus.

*Safe For Topical Use:
Most importantly, Zinc Pyrithione (ZPT) is proven to be a safe agent to introduce to our skin.
Thankfully, Zinc Pyrithione (ZPT) has been approved by the FDA as a safe and effective treatment for dandruff for over 60 years.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE (ZPT):
Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262

Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010

Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.

Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010

Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available

Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262


FIRST AID MEASURES of ZINC PYRITHIONE (ZPT):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE (ZPT):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE (ZPT):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE (ZPT):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE (ZPT):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE (ZPT):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC PYRITHIONE 48%
ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) IUPAC name bis(2-pyridylthio)zinc 1,1'-dioxide ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Other names ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT , ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CAS Number 13463-41-7 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) monomer: Interactive image ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) dimer: Interactive image ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) ECHA InfoCard 100.033.324 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) 3005837 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) UNII R953O2RHZ5 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CompTox Dashboard (EPA DTXSID7026314 Edit this at Wikidata ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Properties ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Chemical formula C10H8N2O2S2Zn ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Molar mass 317.70 g/mol ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Appearance colourless solid ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Melting point 240 °C (464 °F; 513 K) (decomposition)[1] ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Boiling point decomposes ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Solubility in water 8 ppm (pH 7) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 )(or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.[2] Contents 1.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Structure of the compound 2.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Uses 2.1.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Medical 2.2.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In paint 2.3.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In sponges 2.4.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In clothing 3.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Mechanism of action 4.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Health effects 5.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) See also 6.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) References 7.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) External links ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Structure of the compound The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociate via scission of one Zn-O bond.This compound was first described in the 1930s.Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Uses Medical ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos. It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera. Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In paint Due to its low solubility in water (8 ppm at neutral pH), zinc pyrithione is suitable for use in outdoor paints and other products that provide protection against mildew and algae. It is an effective algaecide. It is chemically incompatible with paints relying on metal carboxylate curing agents. When used in latex paints with water containing high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed. Its decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In sponges ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In clothing A process to apply ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) to cotton with washable results was patented in the United States in 1984.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is now used to prevent microbe growth in polyester.Textiles with applied zinc pyrithione ( ÇİNKO PİRİTİON %48 ) protect against odor-causing microorganisms. Export of antimicrobial textiles reached US$497.4 million in 2015. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Mechanism of action Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Health effects ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several antidandruff shampoos. In its industrial forms and strengths, it may be harmful by contact or ingestion. Zinc pyrithione ( ÇİNKO PİRİTİON %48 ) can trigger a variety of responses, such as DNA damage in skin cells. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) See also Selenium disulfide, an active ingredient used in shampoos such as Selsun Blue.Ketoconazole, another antifungal agent used in shampoos.Piroctone olamine, another antifungal agent used in shampoos.ZPT (ZINC PYRITHIONE 48%) ( ÇİNKO PİRİTİON %48 ) is best known for its use in treating dandruff and seborrhoeic dermatitis. It also has antibacterial properties and is effective against many pathogens from the streptococcus and staphylococcus class. Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) is approved for over-the-counter topical use in the United States as a treatment for dandruff. It is the active ingredient in several anti-dandruff shampoos such as Head & Shoulders. However, in its industrial forms and strengths, it may be harmful by contact or ingestion. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Function 1. Used in shampoo dandruff, it can effectively kill produce dandruff of fungi, to play a role of dusting. 2. Also used as a cosmetic preservative agent. 3. Used for Coating biocide. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CAS: 13463-41-7 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Chemical Formula: C10H8N2O2S2Zn ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Molecular Weight: 317.70 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Test Specification WHITE SLIGHTLY VISCOUS LIQUID. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) PH 5% solution = 7.2 (use meter) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Solubility MISCIBLE IN WATER, BUT LIQUID DOES NOT BECOME CLEAR; INSOLUBLE IN ALCOHOL AND ACETONE; SOLUBLE IN DILUTE NAOH. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Specific gravity Z1025, 13463-41-7 SpectrumTM ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ), 48 Percent Aqueous Suspension is a fungistatic and baceriostatic compound that has a variety of uses. It is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH). It is also often used in kitchen sponges as an antibacterial treatment. 48 Percent Aqueous Suspension. Zinc OmadineTM Fine Particle Size (FPS) Fungicide-Algaecide Dispersion (zinc pyrithione)( ÇİNKO PİRİTİON %48 ) Zinc OmadineTM 48% Aqueous Dispersion FPS (Fine Particle Size) offers bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.Zinc OmadineTM products are highly active, broad spectrum antimicrobial agents that are registered around the world for use in both personal care as well as industrial product applications. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) solution for Cosmetic/Antidandruff Additive Product Name: ZINC PYRITHIONE 48%-50% solution( ÇİNKO PİRİTİON %48 - %50 ) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CAS No.:13463-41-7 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Alias: Zinc Pyrithione; Zinc Omadine; Lunacide ZPT 48% Aqueous Dispersion ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Chemical Name: Zinc bis(2-pyridinethiol-1-oxide); Zinc salt of 2-mercaptopyridine-N-oxide ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Biocides, ZPT 48% with the main active ingredient zince pyrithione is effective inhibitors of the growth of fungi and bacteria and also inhibit the growth of molds and yeasts in cosmetic preparations. In addition to this, they exhibit high growth inhibiting activity against a broad spectrum of gram-positive and gram-negative bacteria in cosmetic prepareations. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Lunacide ZPT 48% is 48% aqueous dispersion of Zinc Pyrithione as an active ingredient that has ultra-fine particle of zice pyrithione, a dispersant and a stabilizing agent. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is a superordinary anti-scale agent and anti-lipid overflow agent. It can effectively eliminate eumycete which produces dandruff, and result in relieving itching, removing dandruff, diminishing phalacrosis and deferring poliosis. Therefore, it is considered as a highly effective and safe product. It will add the value of shampoo and meet the high demands from consumers. For this reason, ZPT is widely used in the production of shampoo. Moreover, as a fine, broad-spectrum, environment-friendly and low toxic antiseptics, it can be used in civil coating, adhesive and carpet. The mixture of ZPT and Cu2O also can be used as marine antifouling coating to prevent adhering of shells, seaweeds and aquatic organisms to hulls. ZPT and its relative products enjoy tremendous potential and broad space in pesticide field with properties of high-efficiency, environmental protection, hypotoxicity and broad-spectrum. General Properties: Lunacide ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ): -is a mixture in water of very fine particles of zinc pyrithione( ÇİNKO PİRİTİON %48 ), a dispersant, and a viscosity control agent. -is and effective antidandruff agent. -exhibits pronounced growth inhibiting activity against a broad spectrum of both Gram positive and Gram negative bacteria in cosmetic preparations. -inhibits the growth of fungi, both yeast and mold, in cosmetic preparations. Specifications: Spec. Lunacide ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) Appearance Off-white aqueous dispersion Odor Mild Assay(%) 48-50% Zinc(%) 9.3-11.3% PH(5% In PH 7 water) 6.5-9.0 Bulk Density(gr/ml) 1.2-1.25 Particle Size D90 ≤1um D100≤5um Function: 1. Used in shampoo dandruff, it can effectively kill produce dandruff of fungi, to play a role of dusting. 2. Also used as a cosmetic preservative agent. 3. Used for Coating biocid Dosage: Antidandruff shampoo:1.0~4.0% depending on customer requirements.Marine paint: 3.0~10.0% by weight depending on paint formulation of customer. It can be used together with cuprous oxide or cuprous thiocyanate as a perfect formulation in marine paint. Therapy Nonprescription antiseborrheic shampoos containing zinc pyrithione( ÇİNKO PİRİTİON %48 ) (Head & Shoulders), selenium sulfide (Head & Shoulders Intensive Treatment), or ketoconazole (Nizoral) are the mainstay of treatment. The shampoo must be rubbed into the wet scalp, rinsed, and then reapplied for 3 to 5 minutes before the final rinse. Patients with inflammatory seborrheic dermatitis that has not responded to shampoos benefit from a topical steroid lotion or gel. High-potency steroids should be used sparingly, particularly on the face. Tacrolimus ointment 0.1% or pimecrolimus cream can be used as steroid sparing agents. Therapy for Seborrheic Dermatitis Initial Shampoos - two or three times per week Zinc pyrithione 1% Selenium sulfide 1% or 2.5% Ketoconazole 1% or 2% Hydrocortisone cream 1% or 2.5% b.i.d. as needed ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Alternative Tacrolimus ointment 0.1% or pimecrolimus cream ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Shampoos The two mainstays of topical treatment of SD are tar shampoos and antiyeast shampoos. Antiyeast shampoos consist, in order of potency, of zinc pyrithione, selenium sulfide 1% (over-the-counter shampoos), selenium sulfide 2.5% (prescription), and ketoconazole shampoos (available over the counter in some countries). Tar shampoos have antiinflammatory and antiyeast activity. Children with seborrheic dermatitis If the child has seborrheic dermatitis and curly thick hair, even blond or red, there is a difficulty in applying a medical shampoo. Zinc pyrithione is the most acceptable antidandruff substance for curly hair, because it leads to less drying and stiffness. Avoid ketoconazole shampoo because it causes more friction between the fibers. Sometimes increasing the frequency of shampooing is enough to treat scalp desquamation, even with a regular product. If a medicated shampoo is needed, alternating regiments may be tried first: 1 day with zinc pyrithione and the next day with regular shampoo. It is necessary to apply a conditioner in both situations and rinse it thoroughly. In some countries, scalp solutions with zinc or salicylic acid are available and may be applied as a seborrheic dermatitis treatment instead of a shampoo. When corticosteroids are needed, lotions or creams are better choices than alcoholic solutions vehicles. Avoid conditioning shampoos for those who present with seborrheic dermatitis. The use of astringents or dry shampoos is popular in some countries and may be an option for those who wear hair locks or braids for long periods. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) for Optimization The procedure presented above illustrates a method for imaging cellular zinc that has been optimized in our lab for a particular dye and a cell type. The variety among biological specimens and subtle differences between different probes necessitate optimization of many parameters, in particular, dye concentration and loading time. Among others properties, the permeability of a dye has a pronounced effect. For example, ZPP1, which is less permeable than ZP1, requires 1- to 3-h incubation to achieve full fluorescence turn-on in HeLa cells following treatment with zinc/pyrithione (Buccella et al., 2011). Additionally, it is desirable to use minimum dye concentration to reduce background fluorescence. During live-cell imaging, reduced illumination is preferred both to maintain cell health and to prevent dye photobleaching. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) complex is constituted in situ by combining high-purity zinc salt with sodium pyrithione. When a low-affinity probe such as QZ2 is used for imaging intracellular zinc, a substoichiometric amount of ionophore may be used to avoid its competitive binding with zinc inside cells (Nolan et al., 2005).Although it is convenient to apply directly zinc/pyrithione and TPEN stock solutions in DMSO to the culture dish, mixing DMSO and aqueous media generates heat and the slow diffusion of DMSO often causes nonuniform delivery of mobile zinc. In addition, direct addition of the zinc/pyrithione solution to some media such as Neurobasal may result in precipitation (Nolan et al., 2006). To avoid these issues, DMSO solutions can be first diluted into serum-free medium or PBS before addition to the specimen. For example, one may combine DMSO solutions of ZnCl2 and sodium pyrithione in a 1:2 ratio and dilute 10-fold with DMEM; adding 200 μL of this solution to the dish gives a final zinc concentration of 50 μM. Similarly, diluting 20 mM TPEN stock solution 10-fold with serum-free DMEM and adding 100 μL to the stage yield 100 μM final concentration (Nolan et al., 2006). Moreover, we have observed that dye loading by incubation in DMEM containing only 1% FBS gave better imaging results. Treatment Infantile seborrheic dermatitis spontaneously resolves by the end of the 1st year of life. For infants with disfiguring or symptomatic disease, there are several therapeutic alternatives. Topical agents effective against P. ovale include topical ketoconazole in a cream or shampoo base (Cutsem et al, 1990), shampoos containing 1% zinc pyrithione or 1% to 2.5% selenium sulfide, and propylene glycol (Faergemann, 1988). Propylene glycol is a hygroscopic preservative, with antimycotic activity against P. ovale, that has been widely used for more than a century in foods and cosmetics, but can also rarely cause a contact dermatitis. The safety and efficacy of these products have not been established in infants. Nevertheless, widespread availability and popular use have not produced reports of toxicity. Brief application with daily bathing usually is effective and limits excessive percutaneous absorption. Daily application of 0.5% to 1% hydrocortisone cream is another short-term alternative. Topical zinc in the form of ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ), a common ingredient found in antidandruff shampoos, has also been studied for treatment of hair loss. Zinc pyrithione releases zinc ions, which has anti-inflammatory and antioxidant properties. Zinc ions also inhibit 5α-reductase in the skin.45 A RCT compared 5% minoxidil (twice daily), 1% zinc pyrithione (once daily), a combination of both, and placebo in 200 patients with AGA. In the group treated with zinc pyrithione alone, there was a significant increase in total visible hair count by fiber optic microscopy and computer-assisted hair counts after 9 weeks. However, there was no clinically meaningful global improvement noted by either the investigator or the patients. Minoxidil alone or in combination with zinc was more efficacious than zinc shampoo alone.There is a mixture in many shampoo or dandruff products called ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ). This mixture comes from zinc nitrogen oxygen and sulfur and carries antibacterial. It has been used in the world for about eighty years for dandruff and similar scalp ailments.The antibacterial and anti-fugal mixture that prevents oily on the scalp thus consumes the dandruff in the hair to a large extent. This content has a certain frequency according to the density and hair. If it is used more intensively in this use, it may cause serious harm.For this situation, you should consult a dermatologist when your primary comfort appears. After a recommendation from a specialist physician, the situation regarding the frequency and intensity of use becomes clear.ZINC PYRITHIONE 48% content is used against conditions such as dandruff and scaling with its ability to inhibit the growth of mold, fungi and bacteria. There is a wide variety of products that contain this content and although it is not sold with great creep, it is available from many places. It is not possible to find the product that will emerge in an environment with such freedom. Therefore, when determining such a product, the advice you will receive from a specialist doctor may be more beneficial for you as you know that your situation has been reviewed and you have a certain experience. Measures Before using this medicine, you should inform your doctor about the medicines you are currently using, the medicines you are using without a prescription (e.g. vitamins, herbal supplements, etc.), allergies, your past illnesses and your current health condition (e.g. pregnancy, upcoming surgery, etc.) inform. Certain health conditions can make you more susceptible to the side effects of the medication. Take the steps as directed by your doctor or pay attention to what is written on the product. The dosage depends on your condition. If your condition persists or worsens, notify your doctor. Key issues to consult are listed below. Planning to get pregnant, pregnant or breastfeeding If you use other drugs or over the counter products at the same time, the effects of ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) may change. This may increase the risk of side effects or cause the drug to not work properly. Tell your doctor about all medications, vitamins, and herbal supplements you use so your doctor can avoid drug interactions. Zinc Pyrithione( ÇİNKO PİRİTİON %48 ) may interact with the following drugs and products:Sodium calcium edetate Hypersensitivity to ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) is a contraindication. In addition, ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 )should not be used if you have the following conditions: Allergic reactions storage of ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) Store medicines at room temperature, away from heat and light. Do not freeze medicines unless it is written on the package insert. Keep medicines out of the reach of children and pets.Do not pour medicines into the toilet or sink unless you are told to do so in the package insert. Drugs disposed in this way can pollute the nature. Please consult your pharmacist or doctor for more details on how to safely discard Zinc Pyrithione. Expired ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Taking a single dose of expired ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 )is likely to cause an adverse event. Consult your family doctor or pharmacist for appropriate advice or if you feel unwell. Expired drugs will not be effective in treating the conditions on your prescription. In order to stay safe, it is very important not to use expired medications. If you have a chronic illness that requires constant medication, such as heart disease, seizures, and life-threatening allergies, it is even more important to stay in touch with your GP so that you can replace expired medications immediately.Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociate via scission of one Zn-O bond.This compound was first described in the 1930s.Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.[medical citation needed] It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.[medical citation needed] Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.Due to its low solubility in water (8 ppm at neutral pH), zinc pyrithione is suitable for use in outdoor paints and other products that provide protection against mildew and algae. It is an effective algaecide. It is chemically incompatible with paints relying on metal carboxylate curing agents. When used in latex paints with water containing high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed. Its decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight.Zinc pyrithione is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.A process to apply zinc pyrithione to cotton with washable results was patented in the United States in 1984.Zinc pyrithione is now used to prevent microbe growth in polyester.Textiles with applied zinc pyrithione protect against odor-causing microorganisms. Export of antimicrobial textiles reached US$497.4 million in 2015.Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.Zinc pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several antidandruff shampoos and body wash gels. In its industrial forms and strengths, it may be harmful by contact or ingestion. Zinc pyrithione can trigger a variety of responses, such as DNA damage in skin cells.1. Zinc pyrithione 48 is high-efficiency, environmental protection, hypotoxicity and broad-spectrum. Pyrithione zinc is mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.3. Exhibits pronounced growth inhibiting activity against a broad spectrum of both Gram positive and Gram negative bacteria in cosmetic preparations.4. ZPT 48 inhibits the growth of fungi, both yeast and mold, in cosmetic preparations.An international questionnaire completed by 722 dermatologists assessed the belief of tachyphylaxis incidence with pyrithione zinc (PTZ)-based shampoos, time course, occurrence relative to active ingredients, and effect of switching products. Two double-blind, randomized, clinical evaluations were conducted, 24- and 48-week studies, whereby a 1% PTZ shampoo, a 2% PTZ shampoo, or a matched placebo control shampoo was used by each subject for the duration of the study. Dermatologists assessed the adherent scalp flaking (scale of 0-10) at baseline and at specified intervals. 64% of responding dermatologists believed tachyphylaxis occurred with PTZ products, and most felt that tachyphylaxis occurred within 3 months of use. Evaluation of mean treatment responses vs. placebo and individual responses as a function of study duration showed a consistent benefit for all products at all time points; therefore, no evidence for tachyphylaxis was found (within 48 weeks of treatment) .Dandruff results from at least three etiologic factors: Malassezia fungi, sebaceous secretions, and individual sensitivity ... Of the three etiologic factors implicated in dandruff, Malassezia, sebaceous triglycerides, and individual susceptibility, Malassezia are the easiest to control. Pyrithione zinc kills Malassezia and all other fungi, and is highly effective against the Malassezia species actually found on scalp. Reduction in fungi reduces free fatty acids, thereby reducing scalp flaking and itch.The efficacy and safety of ketoconazole (KET) 2% and zinc pyrithione (ZPT) 1% in shampoo formulations for the alleviation of severe dandruff and seborrheic dermatitis /were compared/. This open randomized, parallel-group trial began with a 2-week run-in phase during which subjects applied a neutral non-antidandruff shampoo. It was followed by a 4-week randomized treatment phase and a subsequent 4-week follow-up phase without treatment. Shampooing during the treatment period was carried out twice weekly for the KET group and at least twice weekly for the ZPT group in accordance with the label instructions. A total of 343 subjects were recruited to enter the trial. Of the 331 eligible volunteers, 171 were randomized to KET 2% and 160 to ZPT 1%. ... Beneficial effects were evidenced for both medicated shampoos, but the effect was significantly better for KET 2%, which achieved a 73% improvement in the total dandruff severity score compared with 67% for ZPT 1% at week 4 (p < 0.02). The recurrence rate of the disease was also significantly lower following KET 2% treatment than following ZPT 1% treatment ... Both formulations were well tolerated.A patient had had stable psoriasis for 25 years and no any other skin disease. Within 20 days, she developed an aggravated scaly erythematous patch on the scalp, where /an antidandruff/ shampoo had been applied, and simultaneously developed pustular psoriasis on both forearms. Patch testing showed a relevant sensitization to zinc pyrithione, and ... symptomatic aggravation by provocation testing with zinc pyrithione shampoo /was observed/...A case of allergic contact dermatitis to a shampoo containing zinc pyrithione associated with an eruption of pustular psoriasis is reported. The patient had had stable psoriasis for 5 years, and never any other skin disease. Within 1 week she developed severe generalized pustular psoriasis with many lesions where the shampoo was applied. Treatment with cyclosporin, 200 to 300 mg daily, cleared the eruption within 4 weeks, except for psoriasis of the scalp. Extensive patch testing revealed a relevant sensitization to zinc pyrithione ...4. 4= very toxic: probable oral lethal dose (human) 50-500 mg/kg, between 1 teaspoon & 1 oz for 70 kg person (150 lb). ... It appears unlikely that the toxicity of this substance can be attributed solely to its zinc content.Twenty-six mature Yorkshire pigs were used in this study. Radiolabeled zinc pyrithione was applied /dermally/ for 8 hr either as a single dose (50,100, and 400 mg/kg) or as a 5 day repeated dose (100 mg/kg). Serial samples of blood, urine, and feces were taken after dosing. Radioassay of necropsy material, urine, blood, and feces showed recovery of 86.8-98.2% of applied radioactivity. Greater than 90% of recovery was obtained from washings of the application site. Urinary excretion was 3% in animals with intact skin. Levels of radioactivity in blood, urine, and feces returned to background by 48 hours post-application. Dermal Absorption Factor: 3%.After IV admin in rabbits (14)C disappeared from blood rapidly, within 6 hr, 75% was excreted into urine while concentration of (65)Zn remained relatively constant with only 0.5% excreted into urine. Tissue concentration of (65)Zn were about 10 times higher than (14)C. Eight hr after dermal application, 0.5% of (14)C was excreted into urine, and same amount was found in major organs of rabbit. Less than 0.002% of applied (65)Zn was found in urine and 0.008% was found in major organs.Zinc pyridinethione was biotransformed in rabbits, rats, monkeys, and dogs after oral dosing into 2-pyridinethiol 1-oxide S-glucuronide and 2-pyridinethiol S-glucuronide.For zinc 2-pyridinethiol-1-oxide (USEPA/OPP Pesticide Code: 088002) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: Some heavy metals are VERY TOXIC POISONS, especially if their salts are very soluble in water (e.g., lead, chromium, mercury, bismuth, osmium, and arsenic). IMMEDIATELY call a hospital or poison control center and locate activated charcoal, egg whites, or milk in case the medical advisor recommends administering one of them. Also locate Ipecac syrup or a glass of salt water in case the medical advisor recommends inducing vomiting. Usually, this is NOT RECOMMENDED outside of a physician's care. If advice from a physician is not readily available and the victim is conscious and not convulsing, give the victim a glass of activated charcoal slurry in water or, if this is not available, a glass of milk, or beaten egg whites and IMMEDIATELY transport victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
ZINC PYRITHIONE 48% AQUEOUS DISPERSION
Zinc Pyrithione 48% aqueous dispersion offers bactericide-fungicide efficacy.
Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chem/IUPAC Name: Pyridine-2-thiol-1-oxide, zinc complex (2:1)
Chemical formula: C10H8N2O2S2Zn



Zinc Pyrithione, 48% Aqueous Dispersion, Zinc Pyrithione 48% Aqueous Dispersion, Zinc Pyritione 48%, Zinc Pyrithione, T/N: Zinc Omadine 48% FPS, Zinc Pyridinethione,



Zinc Pyrithione 48% aqueous dispersion acts as an anti-dandruff and odor-controlling agent.
Zinc Pyrithione, 48% Aqueous Dispersion is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione, 48% Aqueous Dispersion is known for its ability to fight dandruff and promote a healthy scalp.


Zinc Pyrithione, 48% Aqueous Dispersion is a chemical compound consiting of zinc and pyrithione.
Zinc Pyrithione 48% aqueous dispersion is insoluble in water.
Zinc Pyrithione 48% aqueous dispersion is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.


Zinc Pyrithione 48% aqueous dispersion has long been used as anti-dandruff agent and widely used in various popular shampoos.
Zinc Pyrithione 48% aqueous dispersion is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Pyrithione 48% aqueous dispersion can effectively prevent precipitation and double the antimicrobial effect.


Zinc Pyrithione 48% aqueous dispersion offers bactericide-fungicide efficacy.
Zinc Pyrithione, 48% Aqueous Dispersion is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione, 48% Aqueous Dispersion exists as a centrosymmetric dimer.


Zinc Pyrithione, 48% Aqueous Dispersion is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc Pyrithione, 48% Aqueous Dispersion mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.


Zinc Pyrithione, 48% Aqueous Dispersion is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.
Zinc Pyrithione, 48% Aqueous Dispersion, also known as Pyrithione Zinc, is an antibacterial, antimicrobial, and antifungal agent that can be used to treat dandruff, scalp psoriasis, and acne.


Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione 48% aqueous dispersion inhibits the growth of a broad spectrum of both Gram-positive and Gram-negative bacteria.
Zinc Pyrithione 48% aqueous dispersion also inhibits the growth of fungi, yeast, mold, and algae.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione, 48% Aqueous Dispersion works by targeting both local fungi and bacteria residing on the scalp.
This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.


Zinc Pyrithione 48% aqueous dispersion is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent.
At room temperature Zinc Pyrithione 48% aqueous dispersion is white to yellow crystalline powder.


Zinc Pyrithione 48% aqueous dispersion is slight characteristic odor.
Zinc Pyrithione 48% aqueous dispersion is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione 48% aqueous dispersion is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.


Zinc Pyrithione 48% aqueous dispersion works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Zinc Pyrithione 48% aqueous dispersion is slight characteristic odor.


Zinc Pyrithione 48% aqueous dispersion is insoluble in water.
Zinc Pyrithione 48% aqueous dispersion has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
It is active against the bacteria E. coli, Zinc Pyrithione 48% aqueous dispersion reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.


Formulations containing Zinc Pyrithione 48% aqueous dispersion have been used in the treatment of dandruff.
For instance, Zinc Pyrithione, 48% Aqueous Dispersion’s an essential element in kitchen sponges, preventing the growth of mould.
Zinc Pyrithione, 48% Aqueous Dispersion is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.


Zinc Pyrithione, 48% Aqueous Dispersion is known for its ability to fight dandruff and promote a healthy scalp.
Zinc Pyrithione 48% aqueous dispersion is a mixture of ultra-fine particles of zinc pyrithione (ZPT), a dispersant and a stabilizing agent.
Zinc Pyrithione 48% aqueous dispersion is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and
bacterial (gram-positive & gram-negative).


Due to low solubility, Zinc Pyrithione, 48% Aqueous Dispersion released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.
Other uses of Zinc Pyrithione, 48% Aqueous Dispersion include additive in antifouling outdoor paints and algaecide. While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione, 48% Aqueous Dispersion has been reported for decades.


Zinc Pyrithione, 48% Aqueous Dispersion has the ability to inhibit the growth of yeast, which is a major cause of dandruff.
If you're struggling with dandruff or other scalp issues, look for hair care products containing Zinc Pyrithione, 48% Aqueous Dispersion to help alleviate your symptoms and promote a healthy scalp.
Additionally, Zinc Pyrithione 48% aqueous dispersion aids in controlling sebum production, contributing to a healthier scalp environment.


The chemical formula of Zinc Pyrithione 48% aqueous dispersion is C10H8N2O2S2Zn.
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc.
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
Zinc Pyrithione 48% aqueous dispersion is a fungistatic and baceriostatic compound that has a variety of uses.


Zinc Pyrithione, 48% Aqueous Dispersion is a chemical compound derived from the natural element Zinc.
Zinc Pyrithione, 48% Aqueous Dispersion was first developed in the 1930s, then synthesized by E. Shaw in 1950.
So while it does draw from the naturally occurring metal, Zinc Pyrithione, 48% Aqueous Dispersion is ultimately produced in a lab.



USES and APPLICATIONS of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is used in skincare, shampoos, conditioners and leave-on products.
Zinc Pyrithione 48% aqueous dispersion is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione 48% aqueous dispersion is suitable for outdoor coatings and other products that protect against mold and algae.
In addition, Zinc Pyrithione 48% aqueous dispersion is an effective algaecide.


The optimum process conditions were determined by single-factor and orthogonal tests.
The process parameters of cotton fabrics were: Zinc Pyrithione 48% aqueous dispersion mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Pyrithione 48% aqueous dispersion mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Pyrithione 48% aqueous dispersion is used as an additive to protect paints (such as industrial and marine) against
microbe (algal, fungal and bacterial) and crustacean growth.
Zinc Pyrithione 48% aqueous dispersion acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.


Zinc Pyrithione 48% aqueous dispersion can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
As an anti-mildew agent, Zinc Pyrithione 48% aqueous dispersion also has some applications on fabrics.
Therefore, Zinc Pyrithione 48% aqueous dispersion on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


Zinc Pyrithione 48% aqueous dispersion can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.
Zinc Pyrithione 48% aqueous dispersion is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


UV light slowly breaks down Zinc Pyrithione 48% aqueous dispersion, providing years of protection even in direct sunlight.
In the pesticide field, Zinc Pyrithione 48% aqueous dispersion is used mainly to control apple leaf curl and scab, among others.
Zinc Pyrithione 48% aqueous dispersion is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.


In addition, Zinc Pyrithione 48% aqueous dispersion can be used to treat peeling, such as psoriasis, dermatitis and similar skin diseases.
Zinc Pyrithione 48% aqueous dispersion is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.


Zinc Pyrithione 48% aqueous dispersion is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione 48% aqueous dispersion is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.


Pharmaceutical Applications of Zinc Pyrithione 48% aqueous dispersion: Zinc Pyrithione 48% aqueous dispersion is a regulator of keratinization, has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).
Zinc Pyrithione 48% aqueous dispersion has a strong killing effect on fungi and bacteria, can effectively kill the fungus that produces dandruff, and has an anti-dandruff effect.


Zinc Pyrithione 48% aqueous dispersion's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.
For shampoo to remove dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit the growth of gram-positive and negative bacteria and mold.


Zinc Pyrithione 48% aqueous dispersion is used in shampoos to remove dandruff, and can inhibit the growth of Gram-positive and negative bacteria and molds.
Zinc Pyrithione 48% aqueous dispersion can effectively care for the hair, delay the aging of the hair, and control the generation of gray hair and hair loss.


Zinc Pyrithione 48% aqueous dispersion can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
In addition, Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil agent, and paint biocide.
Zinc Pyrithione 48% aqueous dispersion is used as a fungicide for products such as coatings and plastics, it is also widely used.


Zinc Pyrithione 48% aqueous dispersion is a highly effective bactericide-fungicide, the anti-dandruff agent establishes the market standard for any active ingredient solutions in anti-dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion's high antimicrobial efficacy combined with the acceptability for human use has made it the agent of choice for anti-dandruff shampoo manufacturers worldwide.


Zinc Pyrithione 48% aqueous dispersion anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione 48% aqueous dispersion is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.


In addition, an important characteristic of this molecule is that Zinc Pyrithione 48% aqueous dispersion is efficacious against various bacteria species associated with producing odor on the skin.
Zinc Pyrithione 48% aqueous dispersion is a fungistatic and bacteriostatic compound that has a variety of uses.


Zinc Pyrithione 48% aqueous dispersion is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione 48% aqueous dispersion is widely used as a fungicide for paints and plastics.
Zinc Pyrithione 48% aqueous dispersion has unique advantages in environmental friendliness and sterilization persistence.


Therefore, Zinc Pyrithione 48% aqueous dispersion has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Zinc Pyrithione 48% aqueous dispersion can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.


As the name suggests, Zinc Pyrithione 48% aqueous dispersion is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.
Shampoo for dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging,control white hair and hair loss generation.


Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, and paint biocide.
Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus, playing a role in dandruff .


Zinc Pyrithione 48% aqueous dispersion is used Shampoo for dandruff.
Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively , delay hair aging ,control white hair and hair loss generation.


Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .


Zinc Pyrithione 48% aqueous dispersion is used as anti-dandruff agent and bactericide in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.
Zinc Pyrithione 48% aqueous dispersion has strong killing power on fungi and bacteria, can effectively kill the fungi that produce dandruff, and play an anti-dandruff effect.


Zinc Pyrithione 48% aqueous dispersion, as an anti-dandruff agent with a long history, is widely known in the shampoo industry and used by many well-known brands.
In addition, Zinc Pyrithione 48% aqueous dispersion is used in paint to prevent fouling and plugging.


This paint is harmless to the human body and the sea water environment, has a good anti-fouling effect on the organism, and can effectively prevent the sea The equipment is fouled.
Rinse-off body wash products uses of Zinc Pyrithione 48% aqueous dispersion: Bar Soaps, Body wash, Bubble bath.


Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione 48% aqueous dispersion is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.


Zinc Pyrithione 48% aqueous dispersion is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione 48% aqueous dispersion is very effective against a wide variety of pathogenic bacteria/fungus.
Zinc Pyrithione 48% aqueous dispersion is used as a bactericide for coatings and plastics, etc.


Zinc Pyrithione 48% aqueous dispersion has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
Sponges: Zinc Pyrithione 48% aqueous dispersion is an antibacterial treatment for household sponges, as used by the 3M Corporation.


As the name implies, Zinc Pyrithione, 48% Aqueous Dispersion is generated from the chemical element zinc and is utilized in several haircare and skincare products.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione, 48% Aqueous Dispersion is used to treat dandruff and seborrheic dermatitis.


Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.
As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione, 48% Aqueous Dispersion works by targeting both local fungi and bacteria residing on the scalp.


This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.
Zinc Pyrithione 48% aqueous dispersion is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Anti-dandruff agent uses of Zinc Pyrithione 48% aqueous dispersion: Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)


Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Pyrithione 48% aqueous dispersion: Skin care (creams & lotions), Foot creams and Talcs.
Zinc Pyrithione 48% aqueous dispersion is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Pyrithione 48% aqueous dispersion is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione 48% aqueous dispersion is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.


Zinc Pyrithione 48% aqueous dispersion is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.
In recent years, there have been some regulatory updates concerning the use of Zinc Pyrithione 48% aqueous dispersion in personal care and cosmetic products in Asia and globally.


Zinc Pyrithione 48% aqueous dispersion is active against the bacteria E. coli, Zinc pyrithione reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.
Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, paint biocide.


Formulations containing Zinc Pyrithione 48% aqueous dispersion have been used in the treatment of dandruff.Shampoo for dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.



-Zinc pyrithione shampoo:
Zinc Pyrithione 48% aqueous dispersion shampoo is found in many common anti-dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion is antifungal, antibacterial, and antimicrobialTrusted Source, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Zinc Pyrithione 48% aqueous dispersion cream:
Seborrheic dermatitis often affects the scalp, but it can also cause rough, scaly patches on the skin.
Zinc Pyrithione 48% aqueous dispersion cream is used to treat seborrheic dermatitis or psoriasisTrusted Source on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione 48% aqueous dispersion followed by a moisturizer.
You can also use the cream daily by applying Zinc Pyrithione 48% aqueous dispersion in a thin layer to the affected area.


-Clothing uses of Zinc Pyrithione 48% aqueous dispersion:
A process to apply Zinc Pyrithione 48% aqueous dispersion to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione 48% aqueous dispersion is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione 48% aqueous dispersion protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Zinc pyrithione face wash:
Zinc Pyrithione 48% aqueous dispersion face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione 48% aqueous dispersion can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione 48% aqueous dispersion may help clear acne.


-Medicine uses of Zinc Pyrithione 48% aqueous dispersion:
Zinc Pyrithione 48% aqueous dispersion can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione 48% aqueous dispersion also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione 48% aqueous dispersion's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione 48% aqueous dispersion:
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione 48% aqueous dispersion is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione 48% aqueous dispersion is an algaecide.

Zinc Pyrithione 48% aqueous dispersion is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione 48% aqueous dispersion is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione 48% aqueous dispersion is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges: Zinc Pyrithione 48% aqueous dispersion is an antibacterial treatment for household sponges, as used by the 3M Corporation.
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc.
Zinc Pyrithione 48% aqueous dispersion has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


-Clothing uses of Zinc Pyrithione 48% aqueous dispersion:
A process to apply Zinc Pyrithione 48% aqueous dispersion to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione 48% aqueous dispersion is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione 48% aqueous dispersion protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Medicine uses of Zinc Pyrithione 48% aqueous dispersion:
Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione 48% aqueous dispersion also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.

Zinc Pyrithione 48% aqueous dispersion's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione 48% aqueous dispersion:
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione 48% aqueous dispersion is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione 48% aqueous dispersion is an algaecide.

Zinc Pyrithione 48% aqueous dispersion is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione 48% aqueous dispersion is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione 48% aqueous dispersion is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.



WHAT IS ZINC PYRITHIONE 48% AQUEOUS DISPERSION USED FOR?
Zinc Pyrithione 48% aqueous dispersion is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, this ingredient effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Pyrithione 48% aqueous dispersion also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Pyrithione 48% aqueous dispersion’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



HOW TO USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is easily found in many drugstore and supermarket shampoo products.
There are also leave-in treatments available from retail haircare lines.
Depending on the severity of your condition, your dermatologist may recommend a stronger treatment that may need a prescription.


*Use in an anti-dandruff shampoo:
Zinc Pyrithione, 48% Aqueous Dispersion is most often found in anti-dandruff shampoos.
For best results, you should wet your hair and massage the shampoo into your scalp.

Let Zinc Pyrithione, 48% Aqueous Dispersion sit for approximately one minute (or as instructed on the shampoo label) before shampooing the rest of your hair and then rinse out.

Usage will depend on the sensitivity and state of your scalp.
While many shampoos containing Zinc Pyrithione, 48% Aqueous Dispersion can be used daily, I typically recommend using it at least two to three times per week.
For some individuals dealing with seborrheic dermatitis or dandruff,

I often recommend washing the scalp daily or every other day to help eliminate the build-up of oils or dead skin, which may contribute to scaling or flaking.
If someone is concerned about dryness of the scalp, it is okay to use a Zinc Pyrithione, 48% Aqueous Dispersion shampoo a few days per week and a non-medicated shampoo on the alternating days.


*Use in a hydrating conditioner:
Conditioners with Zinc Pyrithione, 48% Aqueous Dispersion can help fight dandruff, itch, and flaking while restoring scalp balance and providing hydration.
After shampooing, massage the conditioner into your scalp and hair and cover Zinc Pyrithione, 48% Aqueous Dispersion with a shower cap.
Leave on for 3 minutes and wash out.
Follow the instructions on the label for the best results.


*Relieve itch and flakes with a serum:
Serums with Zinc Pyrithione, 48% Aqueous Dispersion are great for those with oily scalps or severe flaking and dandruff.
Apply the serum to the scalp in between washes to help with itch and flakes.
Follow the directions on the product, but most can be applied several times a day.


*Apply in a scalp-soothing leave-in cream:
If your scalp tends to get dry, a leave-in cream is often more soothing and moisturizing than a serum.
The creams are often infused with hydrating products like vitamin E and argan oil to protect and moisturize, while the Zinc Pyrithione, 48% Aqueous Dispersion relieves dandruff, itch, and irritation.


STRUCTURE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione 48% aqueous dispersion exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Zinc Pyrithione 48% aqueous dispersion was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



MECHANISM OF ACTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion's antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



FUNCTIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION ARE:
*To combat dandruff,
*To control sebum production,
*Zinc Pyrithione 48% aqueous dispersion helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Pyrithione 48% aqueous dispersionprevents the development of microorganisms in cosmetic products.



BENEFITS OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION FOR HAIR:
Zinc Pyrithione, 48% Aqueous Dispersion is an active ingredient commonly used in anti-dandruff shampoos and personal care products to treat scalp conditions such as seborrheic dermatitis and psoriasis.
Zinc Pyrithione, 48% Aqueous Dispersion is a coordination complex of zinc that contains pyrithione, a biocide with antibacterial and antifungal properties.

Zinc Pyrithione, 48% Aqueous Dispersion works by slowing down the growth of skin cells and reducing the production of yeast, which is a major contributor to dandruff and other scalp conditions.

Zinc Pyrithione, 48% Aqueous Dispersion also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
In addition to its use in personal care products, Zinc Pyrithione, 48% Aqueous Dispersion is also used as an industrial biocide to control the growth of algae and other microorganisms in water-based systems such as paints, coatings, and adhesives.



ACTIVITIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
It is active against the bacteria E. coli, Zinc Pyrithione 48% aqueous dispersion reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.

Formulations containing Zinc Pyrithione 48% aqueous dispersion have been used in the treatment of dandruff.
Shampoo for dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively, delay hair aging, control white hair and hair loss generation.
Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, paint biocide.

Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione 48% aqueous dispersion is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione 48% aqueous dispersion is very effective against a wide variety of pathogenic bacteria/fungus.



MECHANISM OF ACTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion's antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



WHERE IS ZINC PYRITHIONE 48% AQUEOUS DISPERSION FOUND?
Zinc Pyrithione 48% aqueous dispersion is an antibacterial and antifungal agent.
Zinc Pyrithione 48% aqueous dispersion is found in dandruff shampoo and cosmetic products for the treatment of skin problems.



HOW DOES ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORK?
Zinc Pyrithione, 48% Aqueous Dispersion works by targeting the fungus Malassezia, which is a common cause of dandruff and other scalp conditions.
Malassezia is a type of yeast that naturally lives on the scalp and feeds on oils secreted by the hair follicles.

Zinc Pyrithione, 48% Aqueous Dispersion works by disrupting the cell membranes of Malassezia, causing it to die off and reducing its ability to reproduce.
In addition to its antifungal properties, Zinc Pyrithione, 48% Aqueous Dispersion also has antibacterial properties that help to eliminate the bacteria that can contribute to scalp odour.

Zinc Pyrithione, 48% Aqueous Dispersion also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
Zinc Pyrithione, 48% Aqueous Dispersion works by inhibiting the production of cytokines, which are proteins that contribute to inflammation and can cause itching and flaking.

Overall, Zinc Pyrithione, 48% Aqueous Dispersion works by controlling the growth of yeast and bacteria on the scalp, reducing inflammation, and promoting a healthier scalp environment.
This helps to reduce the symptoms of dandruff and other scalp conditions and improve the overall appearance and health of the hair and scalp.



ADVANTAGES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



ALTERNATIVES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
*KETOCONAZOLE,
*SELENIUM SULFIDE



SAFETY PROFILE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
While generally safe for topical use, Zinc Pyrithione 48% aqueous dispersion may cause mild side effects such as skin irritation, redness, or dryness, especially in individuals with sensitive skin.
Prolonged or excessive use can exacerbate these symptoms.
Additionally, some people may experience allergic reactions characterized by itching or swelling.
Zinc Pyrithione 48% aqueous dispersion is advisable to perform a patch test before widespread application and discontinue use if adverse reactions occur.



ORIGIN OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is synthesized through a multistep chemical process.
Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Pyrithione 48% aqueous dispersion undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Pyrithione 48% aqueous dispersion is then filtered, washed, and dried to obtain a fine powder.



APPEARANCE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is a milky white suspension
Zinc Pyrithione 48% aqueous dispersion is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.



FUNCTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is best known for its use in treating dandruff and seborrhoeic dermatitis.



WHAT DOES ZINC PYRITHIONE 48% AQUEOUS DISPERSION DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



PREPARATION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Method 1:
The principle of preparation is that ZnSO4•7H2O reacts with SPT to produce Zinc Pyrithione 48% aqueous dispersion and sodium sulfate.

Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.
The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain
Zinc Pyrithione 48% aqueous dispersion crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Pyrithione 48% aqueous dispersion.


Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.


Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.


Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Pyrithione 48% aqueous dispersion with a yield of about 75%.



SHAMPOO ZINC PYRITHIONE 48% AQUEOUS DISPERSION MARKET: OVERVIEW
Zinc Pyrithione 48% aqueous dispersion, also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by it.

Zinc Pyrithione 48% aqueous dispersion, as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Pyrithione 48% aqueous dispersion shampoo.
Zinc Pyrithione 48% aqueous dispersion is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



PROPERTIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
In the crystalline state, Zinc Pyrithione 48% aqueous dispersion exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



KEY PRODUCT ATTRIBUTES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
– Relieves flaking symptoms of dandruff
– Targets scalp with a slow release for highest efficacy
– Effective dispersion because it is not soluble
– Enhances substantivity to the skin and hair
– Maintains efficacy over long-term use without resistance



BENEFITS AND USES OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is highly effective, keeping in mind that it is gentle and mild on the skin.
Many anti-dandruff shampoos contain Zinc Pyrithione, 48% Aqueous Dispersion.

Zinc Pyrithione, 48% Aqueous Dispersion is antifungal, antibacterial, and antimicrobial, which means it can fight fungus, bacteria, and germs that cause itchy, flaky skin on the scalp.

Zinc Pyrithione, 48% Aqueous Dispersion cream is used to treat psoriasis and seborrheic dermatitis also called dandruff.
Face washes containing Zinc Pyrithione, 48% Aqueous Dispersion can help relieve the redness and irritation caused by seborrheic dermatitis on the face.
Zinc Pyrithione, 48% Aqueous Dispersion can also assist with the greasiness that comes with eczema and seborrheic dermatitis.



WHAT IS ZINC PYRITHIONE, 48% AQUEOUS DISPERSION, AND WHAT IS ZINC PYRITHIONE, 48% AQUEOUS DISPERSION USED FOR?
Zinc Pyrithione, 48% Aqueous Dispersion is a chemical compound with antifungal and antimicrobial properties, used to treat seborrheic dermatitis and dandruff.
Seborrheic dermatitis is believed to result from an inflammatory skin reaction to the overgrowth of Malessezia yeast that commonly lives on the skin surface.

Seborrheic dermatitis causes redness, itching, and skin flaking, including dandruff on the scalp.
Zinc Pyrithione, 48% Aqueous Dispersion is also used off-label to treat tinea versicolor, another fungal skin infection.
Zinc Pyrithione, 48% Aqueous Dispersion is commonly used as the main active ingredient in anti-dandruff shampoos, conditioners, soaps, lotions, and creams available over the counter (OTC).

Zinc Pyrithione, 48% Aqueous Dispersion inhibits yeast growth by increasing the cellular levels of copper and damaging iron-sulfur clusters of proteins that are essential for fungal metabolism and growth.
Zinc Pyrithione, 48% Aqueous Dispersion has a broad spectrum of activity against organisms including fungi, and gram-positive and gram-negative bacteria.



BACTERICIDAL MECHANISM OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Pyrithione 48% aqueous dispersion varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Pyrithione 48% aqueous dispersion is not the same as that of many bactericides, as it kills bacteria without being consumed.



GENERAL PROPERTIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion Antimicrobial:
– Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent
– Zinc Pyrithione 48% aqueous dispersion inhibits the growth of a broad spectrum of both Gram positive and Gram negative bacteria
– Zinc Pyrithione 48% aqueous dispersion inhibits the growth of fungi, both yeast and mold
– Zinc Pyrithione 48% aqueous dispersion inhibits the growth of algae



KEY PRODUCT ATTRIBUTES FOR ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion relieves flaking symptoms of dandruff
Zinc Pyrithione 48% aqueous dispersion targets scalp with a slow release for highest efficacy
Effective dispersion because Zinc Pyrithione 48% aqueous dispersion is not soluble
Zinc Pyrithione 48% aqueous dispersion enhances substantivity to the skin and hair
Zinc Pyrithione 48% aqueous dispersion maintains efficacy over long-term use without resistance



GENERAL PROPERTIES AND APPLICATIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione 48% aqueous dispersion is an effective antidandruff agent.
Zinc Pyrithione 48% aqueous dispersion is the growth of a broad spectrum of both Gram positive and Gram negative bacteria.
Zinc Pyrithione 48% aqueous dispersion inhibits the growth of fungi, both yeast and mold.
Zinc Pyrithione 48% aqueous dispersion inhibits the growth of algae.



WHAT IS ZINC PYRITHIONE, 48% AQUEOUS DISPERSION USED FOR AND HOW DOES ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORK?
Zinc Pyrithione, 48% Aqueous Dispersion is an over-the-counter (OTC) product used to treat dandruff (seborrhea).



HOW ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORKS?
Zinc Pyrithione, 48% Aqueous Dispersion works by inhibiting the growth of yeast, which is the main factor in dandruff.
Zinc Pyrithione, 48% Aqueous Dispersion works by supplying moisture to the skin and scalp, thereby hydrating them.



CONCENTRATION AND SOLUBILITY OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is recommended that it be used at a concentration of 0.5 to 1% for best results.
Zinc Pyrithione, 48% Aqueous Dispersion is soluble in water and alcohol but insoluble in volatile oils.



HOW TO USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Mix Zinc Pyrithione, 48% Aqueous Dispersion with water in the recommended concentration and stir until a homogeneous mixture is created.
Add other surfactants and enhancing ingredients like essential oils, depending on your product and need, and mix properly.
Add this mixture to the warm base of the product and stir until the desired thickness and texture are obtained.



CHEMICAL INCOMPATIBILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Transchelation occurs in the presence of heavy metal ions.
Even traces of the corresponding chelates can cause a noticeable discoloration, foremost the iron and copper complexes.
Zinc Pyrithione 48% aqueous dispersion is sensitive to strong oxidizing and reducing agents.

The Conductivity of water should be less than 5μs/cm Calculate the dosage to ensure that whole barrels of product would be added for each batch.
It is recommended to add a little zinc salt to the water to ovoid occurring Fe(III) complexes when the conductivity of the water is less than 20μs/cm.
Zinc Pyrithione 48% aqueous dispersion is incompatible with EDTA, which, however, does no harm the sterilizing effect of Zinc pyrithione



TYPE OF INGREDIENT OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
*Antifungal,
*antimicrobial,
*antibacterial properties



MAIN BENEFITS OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Treats dandruff, soothes scalp irritation, regulates oil production, and prevents itching.



WHO SHOULD USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is best for those experiencing dandruff or seborrheic dermatitis, which may be associated with an oily scalp.
It is best to consult a dermatologist to determine the cause of your scalp flakes or irritation before using Zinc Pyrithione, 48% Aqueous Dispersion.



HOW OFTEN CAN YOU USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Shampoos containing Zinc Pyrithione, 48% Aqueous Dispersion can be used daily, and those individuals dealing with seborrheic dermatitis or dandruff are often advised to cleanse daily.
If the scalp is dry, it is okay to use a Zinc Pyrithione, 48% Aqueous Dispersion shampoo two to three days per week and a non-medicated shampoo on alternating days.



STABILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion remains stable for 120 hours at 100℃, decomposes at 240℃。
Zinc Pyrithione 48% aqueous dispersion is sensitive to light and remains stable in pigmented coatings.
Zinc Pyrithione 48% aqueous dispersion is hydrolytically stable between pH 4.5 and 9.5.
Below pH 4.5 conversion to pyrithione occurs.
In alkaline solutions (pH > 9.5) conversion to soluble alkali salts occurs.



PRECAUTIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Stores Zinc Pyrithione 48% aqueous dispersion in original container in a dry and cool area away from direct sunlight with temperature between 10℃ and 54℃.
Keep the Zinc Pyrithione 48% aqueous dispersion container tightly closed and sealed until ready for use.

Containers opened must be carefully resealed and kept upright to prevent leakage.
Agitate the barrels every 6 weeks.
Pre-agitate for at least 10 minutes before using.

May be pre-dispersed by a certain amount of water to assure better dispersion.
Calculate the dosage to ensure that whole barrels of the product are added for each batch.



PRODUCT BACKGROUND OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.



PROPERTIES OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is a clarifying shampoo for dry & dandruff-prone hair.
-Effectively cleanses & purifies hair.
Zinc Pyrithione, 48% Aqueous Dispersion helps eliminate itching & controls dandruff while visibly reducing flakes and leaves hair fresh & healthy-looking.

It contains Zinc Pyrithione, 48% Aqueous Dispersion – an active ingredient with antifungal and antibacterial properties, which intensely improves the scalp condition.
Zinc Pyrithione, 48% Aqueous Dispersion combats dandruff, seborrhoea and other undesirable changes.
In addition, bisabolol has antiseptic and anti-inflammatory properties, which soothe and restore comfort.



HOW TO USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Apply Zinc Pyrithione, 48% Aqueous Dispersion to wet hair and massage in.
Rinse thoroughly.
If necessary, repeat the process.
Use Zinc Pyrithione, 48% Aqueous Dispersion daily or as special treatment.



ZINC PYRITHIONE, 48% AQUEOUS DISPERSION IN TOPICAL TREATMENTS:
Zinc Pyrithione, 48% Aqueous Dispersion is an antifungal and antibacterial agent.
That’s what makes Zinc Pyrithione, 48% Aqueous Dispersion so powerful at fighting dandruff — more on that later.
Here are some of the highlights when it comes to using Zinc Pyrithione, 48% Aqueous Dispersion in topical treatments.

*Low Solubility:
A key element of Zinc Pyrithione, 48% Aqueous Dispersion’s power is that it has relatively low solubility, meaning it has staying power on our skin.
Zinc Pyrithione, 48% Aqueous Dispersion stays on our scalps, even after we’ve rinsed our hair of shampoo so that it can continue to fight fungus.

*Safe For Topical Use:
Most importantly, Zinc Pyrithione, 48% Aqueous Dispersion is proven to be a safe agent to introduce to our skin.
Thankfully, Zinc Pyrithione, 48% Aqueous Dispersion has been approved by the FDA as a safe and effective treatment for dandruff for over 60 years.



ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORKS WELL WITH:
Selenium sulfide, another ingredient commonly found in dandruff shampoos stronger than Zinc Pyrithione, 48% Aqueous Dispersion.
Additionally, some individuals may alternate with other Zinc Pyrithione, 48% Aqueous Dispersion ingredients, such as ketoconazole, an antifungal ingredient.



DON’T USE WITH:
There are no known ingredients that negatively interfere with Zinc Pyrithione, 48% Aqueous Dispersion; however, it is advised that you speak to a medical professional before using if you are pregnant or nursing.



WHAT HAIR TYPES CAN USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION?
Our experts agree that Zinc Pyrithione, 48% Aqueous Dispersion is safe for all hair types but would be most beneficial for those experiencing dandruff, seborrheic dermatitis, or other scalp conditions that are aggravated by fungus/yeast.
Some formulations of shampoos and topical scalp products include Zinc Pyrithione, 48% Aqueous Dispersion and hydrating and moisturizing ingredients that would be better for those with dry or color-treated hair.

If you don't have dandruff or other scalp conditions, skipping the products with Zinc Pyrithione, 48% Aqueous Dispersion is best.
The only downside is that Zinc Pyrithione, 48% Aqueous Dispersion could ultimately dry out the hair and scalp slightly and upset a healthier scalp microbiome if there is no dandruff or inflammation.

Zinc Pyrithione, 48% Aqueous Dispersion is always best to speak with a medical professional to evaluate the scalp and determine the best course of treatment.

For those with dry or sensitive skin, it is best to slowly incorporate Zinc Pyrithione, 48% Aqueous Dispersion into a routine and use caution as some dryness and irritation may occur, Garshick explains.
Engelman cautions that it is best to speak to a medical professional if you are pregnant or nursing before using Zinc Pyrithione, 48% Aqueous Dispersion.



BENEFITS OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION FOR HAIR:
The benefits of Zinc Pyrithione, 48% Aqueous Dispersion extend beyond the skin of the scalp.
By improving the health of the scalp, the health of the hair benefits as well.

Zinc Pyrithione, 48% Aqueous Dispersion has the power to treat a variety of issues, including dandruff, itchiness, acne, and scalp psoriasis by targeting the yeast/fungus that is causing the problem.


*Zinc Pyrithione, 48% Aqueous Dispersion fights dandruff-causing fungus:
The antifungal, antimicrobial, and antibacterial properties stop dandruff at its source.
Zinc Pyrithione, 48% Aqueous Dispersion is naturally anti-inflammatory and is also antifungal and antibacterial.

Since dandruff is caused directly by an excessive amount of fungus and yeast living on the scalp, by adding the Zinc Pyrithione, 48% Aqueous Dispersion, you decrease the fungal buildup on the scalp and alleviate the inflammation causing the dandruff.


*Zinc Pyrithione, 48% Aqueous Dispersion prevents itching:
Dandruff is one of the leading causes of scalp itchiness.
By preventing dandruff and eliminating the irritating yeast/fungus that causes it, Zinc Pyrithione, 48% Aqueous Dispersion provides itch relief quickly.


*Zinc Pyrithione, 48% Aqueous Dispersion regulates oil production:
Zinc Pyrithione, 48% Aqueous Dispersion can control the oil production and dandruff often found in those with seborrheic dermatitis.


*Zinc Pyrithione, 48% Aqueous Dispersion improves overall scalp health:
Dandruff disrupts the health of the scalp by clogging follicles with flakes and by causing inflammation and irritation.
Zinc Pyrithione, 48% Aqueous Dispersion is able to improve the overall health of the scalp by preventing and treating dandruff.


*Zinc Pyrithione, 48% Aqueous Dispersion promotes hair growth:
Zinc Pyrithione, 48% Aqueous Dispersion has the potential to impact hair growth.

Since a number of thinning hair and hair loss concerns are related to the scalp, Zinc Pyrithione, 48% Aqueous Dispersion can help clear dead skin cells or conditions that prevent hair growth (clogged hair follicles, psoriasis, etc.) and thus promote fuller, healthier hair.

Garshick agrees and points out a study that showed that daily use of 1 percent Zinc Pyrithione, 48% Aqueous Dispersion shampoo over 26 weeks showed an improvement in hair growth.


*Zinc Pyrithione, 48% Aqueous Dispersion improves overall appearance of hair:
The overall appearance of the hair is heavily influenced by the oiliness of the scalp and the thickness of the hair.
By regulating oil production and encouraging new growth, Zinc Pyrithione, 48% Aqueous Dispersion can boost the overall appearance of the hair.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0

Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available

Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available

Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų

Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314

HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble

Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Appearance: Off white to white dispersion
Zinc pyrithione (%): 48-50
Zinc(%): 9.3-11.3
pH(5%): 6.5-8.5

Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010

Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available

Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262



FIRST AID MEASURES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC RICINOLEATE
ZINC SALICYLATE N° CAS : 16283-36-6 Nom INCI : ZINC SALICYLATE Nom chimique : Zinc Disalicylate N° EINECS/ELINCS : 240-380-7 Classification : Règlementé Restriction en Europe : III/24 Ses fonctions (INCI) Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes
ZINC STEARATE

Zinc stearate is a chemical compound that falls under the category of metal salts or metallic stearates.
Zinc stearate is formed by the reaction of stearic acid (a long-chain fatty acid) with zinc oxide.
The resulting compound, zinc stearate, is a white, finely divided powder that is insoluble in water but dispersible in organic solvents.

CAS Number: 557-05-1



APPLICATIONS


Zinc stearate is commonly used as a mold release agent in the plastics industry to facilitate the smooth ejection of plastic parts from molds.
In the rubber industry, it serves as a lubricant and anti-tack agent during the processing of rubber compounds, preventing adhesion between rubber layers.
Zinc stearate is added to PVC (polyvinyl chloride) formulations to enhance the resin's flow properties and improve its processability.
Zinc stearate acts as a flow aid and anti-caking agent in powdered products, including cosmetics, pharmaceuticals, and food items, to prevent clumping and ensure even distribution.

In the cosmetics industry, zinc stearate is used in eyeshadows, foundations, and face powders to provide a silky texture and improve blendability.
Zinc stearate contributes to the matte finish in makeup products, helping control shine and oiliness on the skin.
Zinc stearate is employed in the formulation of pressed powders and compact cosmetics due to its binding properties.

Zinc stearate finds application in pharmaceutical tablet manufacturing as a tablet binder, aiding in the compression of powders into solid tablets.
Zinc stearate is used as a lubricant in the production of abrasive products like grinding wheels and sandpaper.
In the paint and coatings industry, zinc stearate functions as an anti-settling agent, preventing pigment settling in paint formulations.

Zinc stearate is added to ink formulations to improve flow characteristics and prevent ink transfer issues in printing processes.
Zinc stearate is utilized in the manufacture of crayons and colored pencils to enhance color dispersion and texture.
In the ceramics industry, it is used as a glazing agent to reduce friction and enhance surface finish.

Zinc stearate is an effective anti-blocking agent in the production of plastic films, preventing them from sticking together.
Zinc stearate serves as a processing aid in the extrusion and injection molding of thermoplastics, ensuring smooth processing and uniform product quality.
Zinc stearate can be found in the production of adhesive tapes to improve release properties from the roll.

Zinc stearate is added to latex gloves to prevent sticking and adhesion during manufacturing and packaging.
Zinc stearate is employed in the manufacturing of automotive weatherstripping to enhance flexibility and reduce friction.
In the construction industry, zinc stearate is used as a lubricant in the production of concrete pipe gaskets.

Zinc stearate acts as a desensitizing agent in the manufacture of explosives, reducing sensitivity to friction and impact.
Zinc stearate is utilized in the formulation of thermosetting resins to enhance their processing and handling.
In the foundry industry, it is added to sand cores to improve flowability and reduce defects in castings.
Zinc stearate finds application in the production of polishing compounds for metal, plastic, and glass surfaces.

In the textile industry, it is used as a lubricant in the spinning of synthetic fibers to prevent static and improve fiber handling.
Zinc stearate's diverse applications span multiple industries, making it a valuable and versatile chemical compound for enhancing manufacturing processes and product quality.
In the ceramics and pottery industry, zinc stearate is utilized as a glaze ingredient to control the flow and adhesion of glaze materials during firing.
Zinc stearate is used in the production of printing inks, especially in offset and gravure printing, to improve ink transfer and prevent ink set-off onto adjacent sheets.

Zinc stearate acts as a matting agent in the paint and coating industry, providing a matte finish to paints and coatings.
In the plastics compounding process, it functions as a processing aid to improve the extrusion and molding of plastic products.

Zinc stearate is added to rubber products such as tires and conveyor belts to enhance their processing and reduce friction during manufacturing.
In the paper and paperboard industry, zinc stearate is used as a lubricant and release agent in the production of coated paper.
Zinc stearate serves as a dusting powder in the manufacturing of latex products like gloves and balloons to prevent sticking.

Zinc stearate is employed as a flatting agent in the woodworking industry to reduce glossiness and enhance the finish of wood coatings.
Zinc stearate acts as an anti-blocking agent in the production of plastic bags and films to prevent them from sticking together.
In the pharmaceutical industry, it is used in tablet pressing to improve the flowability and compressibility of tablet formulations.

Zinc stearate is found in the production of thermoplastic elastomers (TPEs) to enhance their processing and mold release properties.
Zinc stearate serves as a lubricant in the manufacture of PVC pipes and fittings to facilitate extrusion and prevent fusion.
Zinc stearate is added to polyolefin films to reduce the coefficient of friction and improve slip properties.

In the textile and fiber industry, zinc stearate is used in spinning processes to reduce static electricity and improve fiber handling.
Zinc stearate is employed as a lubricant and anti-tack agent in the production of latex foam products like mattresses and cushions.
Zinc stearate can be found in the production of automotive and industrial gaskets to improve their handling and installation.
Zinc stearate functions as a release agent in the production of rubber gloves, ensuring easy removal from molds.

Zinc stearate is used as a gloss control agent in the manufacturing of paper coatings and varnishes.
In the foundry industry, it is added to core sand formulations to improve the flowability and release of sand cores.
Zinc stearate is utilized in the production of candles to prevent sticking to molds and enhance burn quality.
Zinc stearate is added to clay bodies in pottery and ceramics to reduce cracking and improve workability.

In the leather and footwear industry, it is used as a lubricant during leather processing and shoe sole production.
Zinc stearate is an essential component in the manufacturing of firework compositions to prevent premature ignition.

Zinc stearate serves as an anti-dusting agent in the production of fertilizer granules to reduce dust formation during handling.
Zinc stearate's versatility and multifunctional properties make it an integral part of various manufacturing processes across industries, contributing to product quality and efficiency.
In the ceramics and pottery industry, zinc stearate is utilized as a glaze ingredient to control the flow and adhesion of glaze materials during firing.

Zinc stearate is used in the production of printing inks, especially in offset and gravure printing, to improve ink transfer and prevent ink set-off onto adjacent sheets.
Zinc stearate acts as a matting agent in the paint and coating industry, providing a matte finish to paints and coatings.
In the plastics compounding process, it functions as a processing aid to improve the extrusion and molding of plastic products.

Zinc stearate is added to rubber products such as tires and conveyor belts to enhance their processing and reduce friction during manufacturing.
In the paper and paperboard industry, zinc stearate is used as a lubricant and release agent in the production of coated paper.
Zinc stearate serves as a dusting powder in the manufacturing of latex products like gloves and balloons to prevent sticking.

Zinc stearate is employed as a flatting agent in the woodworking industry to reduce glossiness and enhance the finish of wood coatings.
Zinc stearate acts as an anti-blocking agent in the production of plastic bags and films to prevent them from sticking together.
In the pharmaceutical industry, it is used in tablet pressing to improve the flowability and compressibility of tablet formulations.
Zinc stearate is found in the production of thermoplastic elastomers (TPEs) to enhance their processing and mold release properties.
Zinc stearate serves as a lubricant in the manufacture of PVC pipes and fittings to facilitate extrusion and prevent fusion.

Zinc stearate is added to polyolefin films to reduce the coefficient of friction and improve slip properties.
In the textile and fiber industry, zinc stearate is used in spinning processes to reduce static electricity and improve fiber handling.
Zinc stearate is employed as a lubricant and anti-tack agent in the production of latex foam products like mattresses and cushions.
Zinc stearate can be found in the production of automotive and industrial gaskets to improve their handling and installation.
Zinc stearate functions as a release agent in the production of rubber gloves, ensuring easy removal from molds.

Zinc stearate is used as a gloss control agent in the manufacturing of paper coatings and varnishes.
In the foundry industry, it is added to core sand formulations to improve the flowability and release of sand cores.
Zinc stearate is utilized in the production of candles to prevent sticking to molds and enhance burn quality.
Zinc stearate is added to clay bodies in pottery and ceramics to reduce cracking and improve workability.

In the leather and footwear industry, it is used as a lubricant during leather processing and shoe sole production.
Zinc stearate is an essential component in the manufacturing of firework compositions to prevent premature ignition.

Zinc stearate serves as an anti-dusting agent in the production of fertilizer granules to reduce dust formation during handling.
Zinc stearate's versatility and multifunctional properties make it an integral part of various manufacturing processes across industries, contributing to product quality and efficiency.
In the manufacturing of fiberglass-reinforced plastics (FRP), zinc stearate is used as a release agent to aid in the demolding of FRP components.

Zinc stearate plays a role in the production of ceramics and porcelain by acting as a lubricant during shaping and forming processes.
In the cosmetics industry, zinc stearate is added to lipstick formulations to improve texture, reduce shine, and enhance color dispersion.
Zinc stearate is used as a lubricant in the manufacturing of lead-acid batteries, aiding in the plate assembly process.

Zinc stearate finds application in the production of automotive parts, such as gaskets and seals, to reduce friction and improve sealing properties.
In the woodworking industry, it is utilized as a sanding aid to prevent clogging of sandpaper during the sanding of wood surfaces.
Zinc stearate is added to printing ink formulations for flexographic and letterpress printing to enhance ink transfer onto substrates.
In the production of PVC flooring and tiles, zinc stearate is used as a processing aid to improve workability and mold release.
Zinc stearate is found in the formulation of deodorant and antiperspirant products to improve texture and reduce greasiness.

Zinc stearate serves as a release agent for the production of rubber rollers used in various industrial applications.
In the creation of 3D printing filaments, it helps improve filament flow properties and prevent nozzle clogging.

Zinc stearate is used as a slip agent in the production of plastic film and sheeting to facilitate winding and unwinding processes.
Zinc stearate can be found in the manufacture of thermal transfer ribbons for barcode and label printing.
Zinc stearate is used as a dusting agent in the production of chewing gum to prevent sticking during processing and packaging.
In the construction industry, zinc stearate is added to cement-based products to reduce water absorption and improve workability.

Zinc stearate is employed in the formulation of graphite lubricants for use in locks, hinges, and mechanical components.
Zinc stearate is added to crayon formulations to enhance color blending and reduce smudging.
In the casting of metal and aluminum parts, it serves as a mold release agent to facilitate part removal.
The compound finds use in the production of foamed plastics, such as PVC foam boards, to improve expansion and cell structure.

Zinc stearate is added to rubber compounds used in the manufacturing of conveyor belts to enhance flexibility and reduce wear.
Zinc stearate is used as an anti-foaming agent in the production of latex paints and coatings.
Zinc stearate is added to ceramic glazes to control the thickness of glaze layers and improve application properties.
In the cosmetics industry, it is employed in the formulation of pressed powder compacts for ease of application.

Zinc stearate is used in the production of thermosetting resins to enhance moldability and surface finish.
Its widespread use in various industries underscores its importance as a versatile and effective additive that improves manufacturing processes and product quality.



DESCRIPTION


Zinc stearate is a chemical compound that falls under the category of metal salts or metallic stearates.
Zinc stearate is formed by the reaction of stearic acid (a long-chain fatty acid) with zinc oxide.
The resulting compound, zinc stearate, is a white, finely divided powder that is insoluble in water but dispersible in organic solvents.

Zinc stearate is commonly used in various industries, including the plastics, rubber, cosmetics, pharmaceuticals, and food industries, due to its unique properties.
Zinc stearate acts as a lubricant, release agent, and anti-caking agent. In the plastics and rubber industries, it is often used as a mold release agent to facilitate the release of molded products from molds.
In cosmetics and pharmaceuticals, it is used as a binding agent in the production of tablets and powders, as well as in makeup and skincare products to improve texture and consistency.

Zinc stearate is a white, odorless, and fine-textured powder.
Zinc stearate is a chemical compound formed from the reaction of stearic acid and zinc oxide.
Zinc stearate is insoluble in water but dispersible in organic solvents.

Zinc stearate is widely used as a versatile industrial chemical.
Zinc stearate is known for its lubricating properties, making it an effective mold release agent in plastics and rubber manufacturing.

Due to its lubricity, it helps prevent sticking and facilitates the easy removal of molded products from molds.
Zinc stearate has a low melting point, which aids in its application as a mold release agent.
Zinc stearate is non-toxic and safe for various industrial and commercial uses.
Zinc stearate acts as an anti-caking agent in powdered products, preventing clumping and ensuring a free-flowing consistency.

In the cosmetics industry, zinc stearate is used in makeup formulations, such as face powders and eyeshadows, to improve texture and blendability.
Zinc stearate contributes to a silky and smooth feel in cosmetics, enhancing the application and finish of makeup products.
Zinc stearate can be found in pharmaceutical tablets and powders, where it serves as a binding agent and helps maintain tablet integrity.

Zinc stearate is used as a flow aid in the pharmaceutical industry to ensure uniform mixing of powders.
In the food industry, zinc stearate is employed as a release agent in the production of chewing gum to prevent sticking to manufacturing equipment.
Zinc stearate is chemically stable and does not react with most substances under normal conditions.

Zinc stearate has a low bulk density, making it suitable for applications where lightweight powders are desired.
Zinc stearate is compatible with a wide range of polymers, including polyethylene, polypropylene, and PVC, in plastics processing.
In the rubber industry, zinc stearate is added to rubber compounds to improve processing and prevent adhesion during mixing.



PROPERTIES


Chemical Formula: C36H70O4Zn
Molecular Weight: Approximately 632.33 g/mol
Appearance: Fine, white powder
Odor: Odorless
Solubility: Insoluble in water
Solubility in Organic Solvents: Soluble in common organic solvents such as alcohols, acetone, and chloroform.
Melting Point: Approximately 120-130°C (248-266°F)
Boiling Point: Decomposes before boiling
Density: Approximately 1.095 g/cm³
pH: Neutral
Flammability: Non-flammable
Refractive Index: 1.43 (approximate)
Particle Size: Typically in the micrometer range
Bulk Density: Varies depending on particle size and compaction



FIRST AID


Inhalation:

Move to Fresh Air:
If someone inhales airborne zinc stearate particles and experiences respiratory discomfort, move them to an area with fresh air immediately to allow for easier breathing.

Provide Oxygen:
If breathing difficulties persist or worsen, seek medical attention promptly.
In the meantime, if trained personnel are available and oxygen is accessible, provide oxygen to the affected person.


Skin Contact:

Remove Contaminated Clothing:
If zinc stearate comes into contact with the skin, remove contaminated clothing and shoes as quickly as possible to prevent further contact and contamination.

Wash Skin:
Wash the affected skin area gently but thoroughly with mild soap and lukewarm water for at least 15 minutes to remove any residual powder.
Avoid using hot water, as it may increase skin absorption.

Seek Medical Attention:
If skin irritation, redness, or rash develops or if there is any sign of an allergic reaction, seek medical attention promptly.


Eye Contact:

Flush Eyes:
If zinc stearate contacts the eyes, immediately flush the eyes with gently flowing, lukewarm water for at least 15 minutes.
Ensure that both eyes are thoroughly rinsed, holding the eyelids open to allow adequate flushing.

Remove Contact Lenses:
If applicable, remove contact lenses during the rinsing process if they can be easily removed.

Seek Medical Attention:
Even if there are no immediate symptoms, seek medical evaluation for eye exposure to ensure there is no damage or delayed effects.


Ingestion:

Do NOT Induce Vomiting:
If zinc stearate is ingested, do not induce vomiting.
Rinse the mouth and lips with water to remove any residual chemical.

Seek Medical Help:
Seek immediate medical attention or contact a poison control center.
Provide them with as much information as possible regarding the type and amount of exposure.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment (PPE), including safety goggles or a face shield, chemical-resistant gloves, a lab coat or protective clothing, and chemical-resistant footwear when handling zinc stearate.
Ensure that PPE is in good condition and properly fitted.

Ventilation:
Use zinc stearate only in a well-ventilated area, such as a fume hood or with local exhaust ventilation.
Adequate ventilation helps to minimize exposure to airborne particles.

Avoid Inhalation:
Avoid inhaling airborne zinc stearate particles.
If airborne exposure is likely, wear a dust mask or respiratory protection as recommended by the safety data sheet (SDS) and local regulations.

Prevent Skin Contact:
Prevent direct skin contact with zinc stearate.
In case of contact, follow the first aid measures and safety procedures outlined in the SDS.

Eye Protection:
Wear safety goggles or a face shield to protect against potential eye contact.
In case of eye contact, follow the recommended first aid procedures.

Handling Equipment:
Use chemical-resistant equipment, including containers, pumps, and transfer hoses, when handling or transferring zinc stearate.
Ensure that all equipment is clean and in good working condition.

Avoid Open Flames and Sparks:
Although zinc stearate is non-flammable, avoid working near open flames, sparks, or other potential ignition sources.
Ensure that electrical equipment is suitable for use in hazardous areas.

Static Electricity:
Prevent the buildup of static electricity by using grounded containers and equipment.
Bond and ground containers before transferring or decanting zinc stearate to minimize the risk of static discharge.

Labeling:
Ensure that containers are properly labeled with the chemical name, hazard warnings, and safety information as required by regulations.


Storage:

Storage Area:
Store zinc stearate in a cool, dry, and well-ventilated storage area, away from direct sunlight and heat sources.
Keep it tightly sealed to prevent moisture absorption.

Temperature:
Store at a temperature below 25°C (77°F) to maintain product stability.
Avoid exposure to extreme temperatures.

Containers:
Use chemical-resistant containers made of materials compatible with zinc stearate, such as high-density polyethylene (HDPE) or glass.
Keep containers tightly closed when not in use.

Labeling:
Maintain clear and legible labels on storage containers, including the product name, hazard information, and storage instructions.

Separation:
Store zinc stearate away from incompatible materials, such as strong acids, strong bases, oxidizers, and reducing agents, to prevent chemical reactions or contamination.

Security:
Restrict access to authorized personnel only, and store zinc stearate away from areas with heavy foot traffic.

Inventory Control:
Keep an inventory record of the quantity of zinc stearate in storage, along with its usage and disposal information.

Regulatory Compliance:
Comply with local, state, and national regulations regarding the storage and handling of hazardous chemicals, including zinc stearate.

Emergency Equipment:
Ensure that emergency eyewash stations and safety showers are readily accessible in case of accidental exposure.

Spill Control:
Have spill control measures and materials (e.g., absorbents, spill kits) available in case of spills or leaks.



SYNONYMS


Zinc Octadecanoate
Zinc Stearate Technical
Octadecanoic Acid Zinc Salt
Zinc Distearate
Zinc Di(stearoyl)oxide
Stearic Acid Zinc Salt
Zinc(II) Octadecanoate
Zinc Bis(stearate)
Zinc(II) Stearate
Zinc(2+) Octadecanoate
Zinc Soap of Stearic Acid
Zinc(II) Octadecylate
Zinc Fatty Acid Salt
Zinc(II) 18-hydroxyoctadecanoate
Stearato de Zinc (Spanish)
Stéarate de Zinc (French)
Zinkstearat (German)
Stearato di Zinco (Italian)
Zinkstearaat (Dutch)
Zinkstearat (Swedish)
Zinc(2+) Stearate
Zinc Stearic Acid
Zinc Octadecylate
Zinc Fatty Acid
Zinc Palmitate Stearate
Zinc C18
Zinc Stearate Powder
Zinc Soap
Zinc Soap of Fatty Acid
Zinc Salt of Octadecanoic Acid
Zinc Salt of Stearic Acid
Zinc Salt of Palmitic Acid
Zinc(II) Octadecyl Hexadecanoate
Zinc(II) Octadecyl Palmitate
Zinc(II) Stearic Palmitic Acid
Zinc Octadecanoate Palmitate
Zinc Octadecanoate Octadecylate
Zinc Fatty Acid Soap
Zinc Octadecanoic Acid Ester
Zinc Stearate Ester
Zinc Soap of Octadecanoic Acid
Zinc Soap of Stearic Palmitic Acid
Zinc Octadecanoate Palmitate Stearate
Zinc(II) Octadecyl Stearate
Zinc Octadecanoate Palmitate Hexadecanoate
Zinc Octadecyl Stearate
Zinc Octadecanoate Palmitate Stearate
Zinc Soap of Octadecyl Palmitate
Zinc Soap of Hexadecanoic Acid
Zinc Stearate Palmitate
Zinc Stearate Palmitic Acid
Zinc Stearate Octadecylate
Zinc Stearate Octadecanoate Hexadecanoate
Zinc Palmitate Octadecylate
Zinc Palmitate Octadecanoate Stearate
Zinc Palmitate Stearate Octadecanoate
Zinc Hexadecanoate Octadecanoate
Zinc Octadecyl Palmitate Stearate
Zinc Octadecyl Palmitate Hexadecanoate
Zinc Octadecanoate Palmitate Stearate Hexadecanoate
Zinc Octadecanoate Palmitate Stearate Octadecylate
Zinc Octadecyl Hexadecanoate Palmitate Stearate
Zinc Octadecyl Hexadecanoate Palmitate
Zinc Octadecanoate Palmitate Stearate
Zinc Palmitate Stearate Octadecylate Hexadecanoate
Zinc Stearate Octadecyl Palmitate Hexadecanoate
Zinc Octadecyl Palmitate Octadecanoate
Zinc Octadecyl Hexadecanoate Palmitate Stearate Octadecanoate
Zinc Octadecyl Hexadecanoate Octadecanoate
Zinc Octadecyl Palmitate Stearate Octadecanoate Hexadecanoate
ZINC STEARATE

Zinc stearate is a chemical compound with the molecular formula Zn(C18H35O2)2.
Zinc stearate is a zinc salt of stearic acid, which is a saturated fatty acid.
Zinc stearate is a white, fine powder that is insoluble in water.
Zinc stearate is a common type of metallic stearate and is widely used in various industrial applications.

CAS Number: 557-05-1
EC Number: 209-151-9



APPLICATIONS


Zinc stearate is commonly used as a mold release agent in the plastics industry, facilitating the easy removal of molded parts from the molds.
Zinc stearate is added to PVC (polyvinyl chloride) compounds to act as a lubricant and processing aid, improving the flow of the material during extrusion and molding.
In the rubber industry, zinc stearate is employed as a mold release agent for various rubber products, including tires, gaskets, and seals.

Zinc stearate is used in the production of polyolefin compounds, such as polyethylene and polypropylene, to enhance processing and flow properties.
In the cosmetics industry, zinc stearate is a common ingredient in makeup products like eyeshadows, blush, and foundation, where it contributes to their smooth texture and application.
Zinc stearate serves as a binding and lubricating agent in the cosmetics and pharmaceutical industries, aiding in the compression of powders into solid dosage forms like tablets and pressed powders.

In the paint and coatings industry, zinc stearate is added to formulations as a dispersing agent, ensuring the even distribution of pigments and fillers.
Zinc stearate is used in the production of water-based coatings to improve their gloss and color stability.
Zinc stearate is found in the manufacturing of printing inks, where it helps to disperse pigments and enhance print quality.

In the textile industry, it is utilized as a spinning and weaving aid, reducing friction and static electricity during fabric production.
Zinc stearate can be added to fabric softeners to provide a soft and smooth feel to textiles.
Zinc stearate is employed in the food industry as an anti-caking agent in powdered food products like spices, sugar, and cocoa powder.
Zinc stearate is used in the pharmaceutical industry to coat pills and tablets, ensuring they do not stick together and are easy to swallow.

In the production of rubber gloves, zinc stearate helps to release the gloves from molds, making their production more efficient.
Zinc stearate is used in the construction industry in drywall joint compounds to improve their workability and ease of application.

Zinc stearate serves as a lubricant and release agent in the production of friction materials, such as brake pads and clutch facings.
Zinc stearate can be found in the manufacturing of ceramic glazes, where it helps to disperse and suspend ceramic particles evenly.
In the automotive industry, it is used as a mold release agent for plastic and rubber components, including automotive seals and gaskets.
Zinc stearate is employed in the production of wax crayons to enhance their smoothness and resistance to crumbling.

Zinc stearate is used as a dusting agent in the rubber industry to prevent the sticking of rubber sheets and compounds.
In the adhesive industry, zinc stearate can be added to hot melt adhesives to improve their tack and adhesion properties.

Zinc stearate is found in the production of flame-retardant compounds for plastics, aiding in flame resistance.
Zinc stearate is used in the manufacture of putty and spackling compounds to improve their consistency and ease of application.

In the ceramic industry, it helps to reduce the tendency of glazes to run during firing.
Zinc stearate has applications in various other industries, including ceramics, foundry, and agriculture, where its lubricating, anti-caking, and release properties are beneficial.

In the foundry industry, zinc stearate is used as a parting agent to prevent sand molds from sticking to patterns and core boxes during casting.
Zinc stearate is added to industrial coatings and sealants to improve their performance and durability.
Zinc stearate is employed as a release agent in the production of fiberglass reinforced plastic (FRP) and composite materials.
In the ceramics industry, it serves as a glaze suspension aid, preventing settling and ensuring an even application.

Zinc stearate is utilized in the production of insulating materials, such as electrical insulating varnishes and tapes.
Zinc stearate is added to rubber compounds for wire and cable insulation to enhance flexibility and reduce friction.
Zinc stearate can be found in the formulation of adhesives and sealants, where it improves bond strength and prevents adhesive transfer.

In the paper and pulp industry, it is used as a pitch control agent to prevent the buildup of sticky substances on machinery.
The pharmaceutical industry uses zinc stearate in the manufacturing of powders for tablets and capsules to aid in their flowability and compression.

Zinc stearate is employed in the production of thermoplastic elastomers (TPEs) to improve processing and end-product properties.
Zinc stearate is used in the production of thermosetting plastics and resins to control viscosity and aid in molding.
In the aerospace industry, it can serve as a lubricant and release agent for plastic and rubber components.

Zinc stearate is added to silicone rubber formulations to improve mold release properties.
Zinc stearate is used in the production of soundproofing materials, such as acoustic foams and barriers.

In the casting of concrete and cement-based products, it acts as a surface conditioner to enhance the release of molds and formwork.
Zinc stearate is employed in the production of wax candles and is often found in scented and decorative candles.
In the manufacture of plastic toys, zinc stearate can be used to improve the flow of plastic materials in injection molding.

Zinc stearate is used in the formulation of lubricating greases to reduce friction and enhance lubrication.
Zinc stearate is found in the production of polymer-clay nanocomposites, where it improves the dispersion of clay particles in polymer matrices.

Zinc stearate can be added to polymer compounds used in cable manufacturing to reduce friction and improve flexibility.
Zinc stearate is used in the creation of PVC foam products, including foam boards and sheets.

In the woodworking industry, it can act as a wood dust suppressant, preventing the buildup of dust during cutting and sanding.
Zinc stearate is employed in the production of rubber gaskets and seals for various industrial applications.

Zinc stearate can be added to powder coatings to enhance flow properties and prevent agglomeration.
In the agricultural sector, Zinc stearate is used in crop protection products to improve the dispersion and efficacy of active ingredients.

Zinc stearate is used as a clarifying agent in the plastic industry to enhance the transparency of plastic materials, such as PVC films and sheets.
In the rubber industry, it finds applications in the production of rubber tires, where it acts as a mold release agent and improves the manufacturing process.
Zinc stearate is found in the formulation of rubber conveyor belts, where it aids in processing and contributes to belt longevity.

Zinc stearate is employed in the production of composite decking materials, enhancing their weather resistance and surface finish.
Zinc stearate is used in the paper and packaging industry as a coating component to improve the smoothness and printability of paper.
The cosmetic industry uses zinc stearate in various skincare products, such as lotions and creams, where it contributes to a smooth and creamy texture.

Zinc stearate can be found in the production of sunscreen products, providing a non-greasy feel and improved spreadability.
In the manufacturing of plastic pipes, zinc stearate acts as a lubricant and processing aid during extrusion.
Zinc stearate is used in the formulation of oil-based drilling fluids in the oil and gas industry to prevent caking and improve lubrication.

In the construction industry, it is added to concrete and cement-based mortars to enhance workability and prevent water segregation.
Zinc stearate is utilized in the production of automotive soundproofing materials, reducing road noise and vibration.
In the ceramics industry, it serves as a glaze suspension aid for pottery, tiles, and sanitaryware.

Zinc stearate is used as an anti-tack agent in the manufacturing of rubber gloves and balloons.
Zinc stearate can be added to automotive polishes and waxes to improve their spreadability and gloss.
Zinc stearate is employed in the textile industry to reduce friction in the spinning and weaving processes.
In the fabrication of plastic film and sheet products, it aids in processing and contributes to a smooth surface finish.

Zinc stearate is used in the production of plastic compounds for the electrical and electronics industry to improve insulation and processing.
In the food industry, it functions as an anti-caking agent in powdered food products, such as powdered sugar and spice blends.

Zinc stearate is found in the formulation of inkjet printing inks to disperse pigments and improve print quality.
In the production of ceramic coatings for cookware, it helps to prevent sticking and improve non-stick properties.

Zinc stearate is used in the manufacture of dry powder fire extinguishing agents to enhance flowability.
Zinc stearate can be added to plastic films used in greenhouse construction to reduce surface friction and improve durability.
In the adhesive industry, zinc stearate can act as a viscosity regulator in hot melt adhesives.

Zinc stearate is used in the foundry industry as a sand mold and core release agent for casting metal parts.
Zinc stearate finds applications in the production of automotive components, including rubber seals, gaskets, and grommets, improving their mold release and surface finish.
Zinc stearate is used in the production of plastic films for agricultural greenhouse coverings, where it enhances surface properties and resistance to sticking.

In the ceramics industry, it is employed as a lubricating agent for clay extrusion and plastic forming processes.
The pharmaceutical industry uses zinc stearate in the production of vitamin and mineral supplements in tablet form to aid in the tabletting process.

Zinc stearate is added to wood coatings and stains to improve dispersion of pigments and extend the open time for application.
In the aerospace industry, zinc stearate is used as a release agent for composite materials in the fabrication of aircraft components.
Zinc stearate is utilized in the production of rubber conveyor belts, where it enhances the release of molded rubber sheets.

The textile industry employs zinc stearate as a spinning and weaving aid to reduce friction during textile manufacturing.
Zinc stearate is added to textile softeners to impart a soft and smooth finish to fabrics.

In the construction industry, zinc stearate is used in drywall joint compounds to improve workability and surface finish.
Zinc stearate can be found in oil-based paints, contributing to their stability and preventing settling of pigments.
In the manufacturing of building insulation materials, it aids in the processing of insulating foams and panels.

Zinc stearate is utilized in the production of automotive undercoatings and sealants to improve moisture resistance.
The cosmetic industry incorporates it into skincare products, such as creams and lotions, to provide a silky and non-greasy feel.

Zinc stearate is added to dental waxes to enhance their carving and molding properties.
In the production of rubber rollers used in printing and paper industries, zinc stearate improves mold release and surface quality.

Zinc stearate is employed in the manufacturing of inkjet printing inks to disperse pigments and enhance color vibrancy.
Zinc stearate can be found in the formulation of thermal transfer ribbons, aiding in ink transfer and print quality.
Zinc stearate is used in the fabrication of pressure-sensitive adhesive tapes to reduce friction and prevent adhesion to the roll.
In the agriculture industry, it can be found in pesticide formulations to improve dispersion and spreading of active ingredients.

Zinc stearate is added to plastics used in consumer goods, such as kitchenware and toys, to enhance processing and surface finish.
Zinc stearate is used in the production of foundry core binders to improve core strength and shakeout properties.
Zinc stearate can be found in the production of candles, where it acts as a mold release agent and improves burning characteristics.
In the woodworking industry, it is used in sanding aids to reduce friction and prevent clogging of sandpaper.

Zinc stearate is employed in the manufacture of ceramic fiber products, enhancing their processing and insulation properties.
Zinc stearate is added to rubber-based adhesives to improve tack and prevent the sticking of adhesive-coated surfaces.



DESCRIPTION


Zinc stearate is a chemical compound with the molecular formula Zn(C18H35O2)2.
Zinc stearate is a zinc salt of stearic acid, which is a saturated fatty acid.
Zinc stearate is a white, fine powder that is insoluble in water.
Zinc stearate is a common type of metallic stearate and is widely used in various industrial applications.

Zinc stearate is known for its low solubility in polar solvents and its ability to act as a lubricant, release agent, and stabilizer in various materials.
Zinc stearate is often used as a mold release agent in the plastics and rubber industries, as a lubricant in the production of polyolefin and PVC compounds, and as an anti-caking agent in powdered products.

In addition to its role in industrial applications, zinc stearate is also used in the cosmetics and pharmaceutical industries, where it serves as a binding and lubricating agent in various products, including makeup, powders, and tablets.
Zinc stearate is derived from the reaction of stearic acid and zinc oxide.
Zinc stearate is a metallic stearate, characterized by its salt-like structure.

Zinc stearate is insoluble in water, making it a hydrophobic substance.
Zinc stearate has a melting point in the range of 120 to 130 degrees Celsius (248 to 266 degrees Fahrenheit).
Zinc stearate is known for its low solubility in polar solvents, such as water and alcohols.

Zinc stearate is highly stable under normal storage conditions, with a long shelf life.
The fine, powdery texture gives it a smooth and slightly slippery feel when touched.

Zinc stearate is commonly used as a mold release agent in the plastics and rubber industries.
Zinc stearate is added to polymer compounds to improve flow and release properties during molding.

In the PVC (polyvinyl chloride) industry, zinc stearate acts as a lubricant and processing aid.
Zinc stearate is known for reducing friction during polymer processing, preventing sticking and improving moldability.
Zinc stearate is often used in the production of polyolefin compounds, such as polyethylene and polypropylene.
As an anti-caking agent, it is employed in powdered products to prevent clumping and ensure flowability.

Zinc stearate is used in the cosmetics industry as a binding and lubricating agent in makeup products.
Zinc stearate is found in various cosmetics, including pressed powders, eyeshadows, and blush.

In the pharmaceutical industry, zinc stearate is used as a lubricant in tablet and pill formulations.
Zinc stearate aids in the compression of powdered ingredients into solid dosage forms.
Zinc stearate is also used in the production of printing inks and paints.

Zinc stearate acts as a dispersing agent and can improve the flow of pigments and fillers in paint formulations.
Zinc stearate is added to various coatings and varnishes to enhance their performance and application properties.
In the textile industry, zinc stearate is employed in fabric softeners and as a processing aid for spinning and weaving.

Zinc stearate can act as a release agent in the production of rubber gloves and other rubber products.
Zinc stearate is known for its low toxicity and is generally regarded as safe for various applications.
Its unique properties, including its lubricating and release qualities, make it a valuable additive in a wide range of industrial and consumer products.



PROPERTIES


Physical Properties:

Chemical Formula: Zn(C18H35O2)2
Molecular Weight: Approximately 631.33 g/mol
Appearance: White, fine powder
Odor: Odorless
Taste: Tasteless
Melting Point: Typically in the range of 120 to 130 degrees Celsius (248 to 266 degrees Fahrenheit)
Density: Approximately 1.1 g/cm³
Solubility: Insoluble in water and polar solvents
Solubility in Organic Solvents: Soluble in various nonpolar solvents, such as organic solvents like ethanol, methanol, and chloroform.
pH: Typically neutral (around 7)
Particle Size: Typically a fine, powdery texture
Flammability: Non-flammable


Chemical Properties:

Chemical Structure: Zinc stearate is a metallic stearate, composed of zinc ions (Zn²⁺) bonded with stearic acid molecules (C18H35O2).
Stability: The compound is stable under normal storage conditions.
Reactivity: It is generally non-reactive with common materials and chemicals.
Hygroscopicity: Low hygroscopicity, meaning it has a low tendency to absorb moisture from the environment.



FIRST AID


Inhalation:

Move the affected person to fresh air.
If breathing is difficult, administer artificial respiration.
Seek medical attention if breathing problems persist.


Skin Contact:

Remove contaminated clothing and wash the affected skin with plenty of soap and water.
If irritation occurs, seek medical attention.


Eye Contact:

Rinse the eyes with gentle, lukewarm water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention if eye irritation persists.


Ingestion:

If swallowed: Do not induce vomiting.
Rinse the mouth and drink plenty of water if the person is conscious.
Seek immediate medical attention.
Never give anything by mouth to an unconscious person.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment, including safety glasses or goggles, protective gloves, and suitable protective clothing to minimize skin and eye contact.

Ventilation:
Work in a well-ventilated area, such as under a chemical fume hood or in an area with local exhaust ventilation, to minimize the inhalation of airborne particles.

Avoidance of Dust:
Minimize the generation of dust.
Handle zinc stearate with care to prevent the release of fine particles into the air.

Avoid Contact:
Avoid skin and eye contact with the substance.
In case of contact, follow the recommended first aid measures.

Wash Hands:
Wash hands and any exposed skin thoroughly after handling zinc stearate, especially before eating, drinking, smoking, or using the restroom.

Prevent Ingestion:
Do not eat, drink, or smoke while handling the substance.
Avoid ingestion or oral exposure.

Separate from Incompatible Materials:
Store zinc stearate away from incompatible materials and conditions, including strong acids, strong bases, and sources of ignition.

Proper Labeling:
Ensure that containers of zinc stearate are properly labeled with clear identification, hazard information, and safety instructions.


Storage:

Storage Conditions:
Store zinc stearate in a cool, dry, and well-ventilated area.
Keep it away from heat, open flames, and direct sunlight.

Temperature Control:
Maintain storage temperatures within the specified range to prevent any alterations in the substance's properties.

Containers:
Use suitable, tightly sealed containers for storage to prevent contamination and moisture absorption.

Separation:
Store zinc stearate separately from materials that are incompatible or reactive with it, as indicated in the safety data sheet.

Stacking:
Do not stack containers too high to avoid crushing and potential damage.

Spill Control:
Have spill control measures in place, such as spill kits and absorbent materials, in case of accidental spills or leaks.

Handling Equipment:
Use appropriate handling equipment, such as scoops or shovels, when transferring zinc stearate to prevent the generation of dust.

Compliance with Regulations:
Comply with all local, state, and federal regulations governing the handling and storage of chemicals, including any waste disposal requirements.


Emergency Procedures:

In case of a spill, contain and clean up the material in a manner that minimizes the generation of airborne dust. Use suitable absorbents and follow waste disposal guidelines.
In the event of a fire, use appropriate fire-fighting equipment and follow standard fire-fighting procedures, such as using dry chemical extinguishers.
In case of exposure or adverse effects, refer to the recommended first aid measures and seek medical attention if necessary.



SYNONYMS


Zinc octadecanoate
Zinc distearate
Zinc di(stearoyl) oxide
Octadecanoic acid zinc salt
Zinc soap
Zinc stearate, tech.
Zinc distearate
Zinc dioctadecanoate
Zinc octadecyl stearate
Zinc octadecyl octadecanoate
Octadecyl zinc stearate
Zinc octadecyl octadecanoate
Zinc C18H35O2C18H35O2
Zinc bis(octadecanoate)
Octadecanoic acid, zinc salt
Zinc octadecyl ester
Zinc stearic acid
Zinc octadecanoate, zinc salt
Zinc C36H70O4
Zinc octadecyl octadecanoate, tech.
Zinc octadecanoate, extra pure
Zinc stearate, powder
Zinc stearate (Chinese)
Zinc stearate (Korean)
Zinc stearate (Arabic)
Zinc octadecyl octadecanoate, technical grade
Zinc di(stearoyl) oxide, technical grade
Zinc soap, technical grade
Zinc stearate, industrial grade
Zinc stearate, commercial grade
Zinc octadecanoate, reagent grade
Zinc distearate, analytical grade
Zinc octadecyl octadecanoate, laboratory grade
Zinc stearate, USP grade
Zinc stearate (Hebrew)
Zinc stearate (Hindi)
ZINC STEARATE
Zinc Stearate is a zinc salt of stearic acid, a naturally occurring fatty acid.
Zinc Stearate is a powerful mold release and hydrophobic .
Zinc Stearate is an external lubricator.
Zinc Stearate is proper to all type rubber and plastic applications.


CAS Number: 557-05-1
EC Number: 209-151-9
MDL number: MFCD00013031
Chemical formula: C36H70O4Zn


Zinc stearate is a "zinc soap" that is widely used industrially.
In this context, soap is used in its formal sense, a metal salt of a fatty acid: in this case stearic acid.
Zinc Stearate is a white solid that repels water.


Zinc Stearate is insoluble in polar solvents such as alcohol and ether but soluble in aromatic hydrocarbons (e.g., benzene) and chlorinated hydrocarbons when heated.
Zinc Stearate is the most powerful mold release agent among all metal soaps.


Zinc Stearate contains no electrolyte and has a hydrophobic effect.
Zinc Stearate is an "activator" for accelerated rubber sulfur vulcanization.
As discovered in the early days of vulcanization, zinc has a beneficial effect on the reaction of the sulfur with the polyolefin.


The stearate is a form of zinc that is highly soluble in the nonpolar medium of the polyolefins.
Zinc stearate is a white, hydrophobic powder with a mild, characteristic odour.
Zinc Stearate is insoluble in polar solvents, but soluble in aromatic compounds and chlorinated hydrocarbons when heated.


In the Pishrochem, zinc stearate is produced from the reaction of stearic acid and zinc salt.
Zinc Stearate is obtained from stearic acid.
Zinc Stearate is a fine, white, silky to the touch powder with the following properties.


Zinc Stearate is very stable under high temperature conditions.
Stearate is insoluble in water, alcohol and ethers.
Zinc Stearate is highly resistant to water, giving it repellent properties.


Zinc Stearate is a very effective release agent.
Zinc Stearate serves as a source of zinc, thus benefiting some processes.
Zinc Stearate is a hydrophobic organometallic zinc compound with numerous industrial uses including soaps and plastics.


Zinc Stearate is one of numerous organo-metallic compounds Organo-Metallic Packaging, Lab Quantity(also known as metalorganic, organo-inorganic and metallo-organic compounds) sold by American Elements under the trade name AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications.


Similar results can sometimes also be achieved with Nanoparticles and by thin film deposition.
Note American Elements additionally supplies many materials as solutions.
Zinc Stearate is generally immediately available in most volumes.


Zinc Stearate is an oleochemical substance featuring a white, powdery appearance.
Also known as zinc soap, Zinc Stearate has the ability to repel water and is insoluble in certain types of polar solvents.
Zinc Stearate is formed by combining stearic acid with zinc oxide, the latter of which is an organic white-powder compound that is insoluble in water.


While it does not produce a strong odor, Zinc Stearate powder does have a slight fatty acid scent.
There are a number of methods employed to manufacture Zinc Stearate.
In addition to the direct method of combining stearic acid with zinc oxide, there is also an indirect method known as precipitation, which entails the formation of a solid from a liquid solution.


The fusion method involves a high-shear process using tightly controlled pressure and temperature conditions.
Zinc Stearate offers a number of chemical properties that are invaluable from a manufacturing perspective.
These include lubricity, compatibility and hydrophobicity (not attracted to water).


Zinc Stearate also features a “sharp” melting point, meaning it liquefies upon melting.
The latter characteristic differentiates Zinc Stearate from other metallic stearate materials.
Zinc stearate is white light fine powder.


Formula is ZN (C17H35COO) 2, molecular structure is RCOOZnOOCR (R is alkyl group of industry stearate), specific gravity is 1.095, ignition point is 900℃, density is 1.095, melting point is 130℃, it has creamy feel.
Zinc Stearate is insoluble in water, alcohol, ether, soluble in hot ethanol, turpentine, benzene and other organic solvents and acids.


Zinc stearate is heated and dissolved in organic solvent, when exposes cold, it becomes jelly, when meets strong acid, it can decompose into stearic acid and corresponding zinc.
Zinc Stearate has lubricity, hygroscopic, non-toxic, slightly irritating, non-polluting, non-hazardous properties.


For zinc stearate is dissolved in benzene and calcium stearate is benzene-insoluble, it is possible to separate the calcium stearate and zinc stearate.
Zinc stearate is not soluble in polar solvents, but when be heated, it is high dissolved in aromatic compound agent chlorinated hydrocarbons.
Zinc stearate is a "zinc soap" that is widely used industrially. In this context, soap is used in its formal sense, a metal "salt" of a fatty acid.


Zinc Stearate is a white solid that repels water.
Zinc Stearate is insoluble in polar solvents such as alcohol and ether but soluble in aromatic hydrocarbons (e.g., benzene and chlorinated hydrocarbons) when heated.


Zinc Stearate is the most powerful mold release agent among all metal soaps.
Zinc Stearate contains no electrolyte and has a hydrophobic effect.
Its main application areas are the plastics and rubber industry where Zinc Stearate is used as a releasing agent and lubricant which can be easily incorporated.


Zinc carboxylates, e.g. basic zinc acetate, adopt complex formulas, and are not simply dicarboxylates of zinc.
Instead the formula for most zinc carboxylates is Zn4O(O2CR)6, consisting of a Zn4O6+ core with carboxylate ligands spanning the edges.
Zinc stearate is a zinc salt made from a fatty acid called stearic acid.


Zinc stearate is basically the zinc salt of stearic acid, which is a long-chain fatty acid.
Stearic acid is a waxy substance that can act as an emollient and an emulsifier, so it can make skin feel softer and can also help ingredients in a formulation mix together nicely so that the experience of applying that product is more elegant.


Zinc stearate, the zinc salt of stearic acid, can also help with hydration, and improve the texture of a cosmetic product, giving it more slip.
There are different types of zinc stearate such as particles, granules, powder, and flakes.
Still, the most used one is the powdered form of zinc stearate due to its very small particle size of the highest quality and its colour is white with a subtle characteristic aroma.


Zinc Stearate is a component that is effortlessly soluble in the liquid, is ultra-fine, and has decent distribution compatibility.
Zinc Stearate is highly caspected & valued by the producers because of the delicate understanding it provides to the final products.
Zinc Stearate has many qualities such as heat resistance, yellowing resistance, amazing transparency, rapid drying quality and improved sandability.


Zinc Stearate is very stable under high temperature conditions
Zinc Stearate is Insoluble in water, alcohol and ethers
Zinc Stearate is extremely resistant to water and provides water-repellent properties


Zinc Stearate is a very effective separating agent
Zinc Stearate serves as a supply of zinc, which is a benefit in some processes.
Zinc stearate is a “zinc soap” that is widely used industrially.


In this context, soap is used in its formal sense, a metal “salt” of a fatty acid.
Zinc Stearate is a white solid that repels water.
Zinc Stearate is insoluble in polar solvents such as alcohol and ether but soluble in aromatic hydrocarbons (e.g., benzene) and chlorinated hydrocarbons when heated.


Zinc Stearate is the most powerful mold release agent among all metal soaps.
Zinc Stearate is a white, hydrophobic powder with a slight, characteristic odor.
Zinc stearate is a zinc soap that is known for repelling water.


The insoluble salt is made of commercial stearic acid, a type of mild fatty acid that is used as an emollient and lubricant.
Zinc Stearate is often combined with zinc oxide.
Zinc, on its own, is known to have antibacterial and antiviral properties.



USES and APPLICATIONS of ZINC STEARATE:
Zinc Stearate is used plastic , rubber construction chemicals and paint industry.
Zinc Stearate is used as sandblasting and flattener in varnish , coating and ink applications.
Also Zinc Stearate is used as water-repellent in beton, rock wool , paper , textile , construction chekmicals and paint industry.


Zinc Stearate is used as mold release and dusting .
Zinc Stearate can be manufactured with demanded particular size and density, according to production process and industry .
Zinc Stearate is used in the following products: coating products, inks and toners, plant protection products.


Other releases of Zinc Stearate into the environment are likely to result from: outdoor use and indoor use (eg machine wash fluids/detergents, automotive care products, paints and coatings or adhesives, fragrances and air fresheners)
Zinc Stearate is used in plastic, rubber, construction chemicals and paint industry.


The main related fields of application of Zinc Stearate are the plastics and rubber industries, which are used as release agents and lubricants that can be easily combined.
Zinc stearate is used as an acid breaker and process aid in some polyolefins.


In the construction industry, Zinc Stearate is used zinc stearate as a hydrophobic agent for gypsum, and due to the created properties, such as the final product with a smooth surface and low friction, high resolution and thermal stability, they are special and suitable for PS crystalline grade impactability and other transparent polymer (PE, PS, PVC, SMC, BMC).


The paint and coating industry uses zinc stearate to suspend pigments and improve grinding (powdering ability) and opacity.
Zinc Stearate is used as a water repellent agent.
Zinc Stearate is used as a lubricant for coating papers and sandpaper.


Zinc Stearate is used as an additive in food, pharmaceutical and cosmetic industries.
Zinc Stearate is also commonly used as a raw material with other stearate salts such as calcium stearate, barium, etc.
Zinc Stearate is used for thermal stability of PVC.


The application of zinc stearate in the rubber industry is the masterbatch color of volcanic powders.
Zinc stearate is also used in the coatings and construction chemicals industries.
Its main application areas are the plastics and rubber industry, where Zinc Stearate is used as a releasing agent and lubricant which can be easily incorporated.


Zinc Stearate is widely used as a release agent for the production of many kinds of objects: rubber, polyurethane, polyester processing system, powder metallurgy.
These applications exploit Zinc Stearate's "non-stick" properties.


In cosmetics, Zinc Stearate is a lubricant and thickening agent used to improve texture.
Being lipophilic, Zinc Stearate functions as a phase transfer catalyst for the saponification of fats.
Zinc Stearate is a powerful mould release agent, external lubricant and dispersing agent for plastic and rubber applications.


Its high clarity makes Zinc Stearate suitable for polystyrene resins.
Zinc Stearate can be either veg or tallow-based — veg-based materials come from vegetable sources, while tallow-based materials are extracted from animal sources.


Like all Metallic Stearates, Zinc Stearate has many industrial applications.
The USP grade can be used in pharmaceutical, nutraceutical and cosmetic applications when used according to CFR 21 and FDA guidelines.
The main application areas are plastics and rubber industry, Zinc Stearate is used as lubricant and release agent for excellent compatibility.


Zinc stearate can be used as rubber products soften lubricants, textiles lighting agent, PVC stabilizers.
Zinc Stearate can be used as stabilizer in polyvinyl chloride plastics, rubber softener.
Zinc stearate can be used in the pharmaceutical industry, preparation of solidified oil and lubricants, it can be also used as paint drying agent.


Non-toxic products for PVC and rubber processing, the synergy of calcium stearate and barium stearate can effectively improve PVC and rubber for light and heat stability, PVC processing amount is usually <1; Zinc Stearate can be used for touch agent of rubber products.
Zinc Stearate can also be used as polymeric additive of PP, PE, PS, EPS and pencil manufacturing, it is generally used in the amount of 1 to 3 parts.


How to remove residual zinc stearate of aluminum surface processing
Zinc Stearate is generally used polish manner to treat residual zinc stearate.
Zinc Stearate maybe damage the substrate when uses lure acid.


Zinc Stearate is used glue the pink plastic lubricants.
Zinc stearate is used as PVC stabilizers.
When coordinates with barium-cadmium soap, it is mainly used in soft products, characteristic is that it can restrain initial coloration and avoid sulfide pollution.


Zinc stearate can also be used styrene (polystyrene and ABC, SAN resins), phenolic resins, amino resins and plastics and other heat-curing polyester plasticizer, lubricant and release agent of transparent products.
In the rubber industry, Zinc Stearate can be used as rubber lubricants and anti-blocking agent, curing catalyst media activator.


Zinc Stearate can be used as lighting agent of textile products.
Zinc Stearate can be used as flatting agent in enamel paint industry.
Zinc Stearate is used in Rubber, Plastic, Poyester, Abbrasive, Coating, Printing Inks and PVC Industries.


Zinc Stearate is used in tablet manufacture; in cosmetic and pharmaceutical powders and ointments; as a flatting and sanding agent in lacquers; as a drying lubricant and dusting agent for rubber; as a plastic mold releasing agent; as a waterproofing agent for concrete, rock wool, paper, textiles.
Zinc Stearate is used in cosmetic formulations to increase adhesive properties.


Zinc Stearate is also used as a colouring agent.
This is a mixture of the zinc salts of stearic and palmitic acids.
Zinc Stearate is widely used as a release agent for the production of many kinds of objects rubber, poly urethane, poly ester processing system, powder metallurgy.


These applications exploit Zinc Stearate's "non-stick" properties .
In cosmetics, zinc stearate is a lubricant and thickening to improve texture.
Zinc Stearate is an "activator" for rubber vulcanization by sulfur and accelerators.


As discovered in the early days of vulcanization, zinc has a beneficial effect on the reaction of the sulfur with the polyolefin.
The stearate is a form of zinc that is highly soluble in the nonpolar medium of the poly olefins.
Being lipophilic, Zinc Stearate functions as a phase transfer catalyst for the saponification of fats.


Zinc Stearate is probably the most commonly used binding agent in powder makeup products such as face powders or eyeshadows.
Zinc Stearate gives very good adherence qualities meaning it helps powders to stick together in the pan and to stick to the skin on application.
Zinc Stearate is typically used at 3-10%, too much of it though can cause lumpiness or greasiness on the skin.


Zinc Stearate isn’t exactly one of those ingredients that rolls off the tongue.
And Zinc Stearate probably doesn’t ring a bell when you hear the name.
But don’t let that fool you—this cosmetics ingredient, Zinc Stearate, is everywhere.


Zinc Stearate has been used as a binding agent in powdered cosmetics (like powders, blushes, and eyeshadows), as a thickening agent, and as a lubricant.
Zinc Stearate, a totally non-toxic zinc compound, comes with various industrial applications and standard aromas.
Zinc Stearate primarily works as a release & thickening agent and emulsifier and it is a vital component in the packaging, construction, consumer goods, automotive and several other industries.


Zinc Stearate is also known as "zinc soap" and it is broadly used in many industries.
The most common soaps, Zinc Stearate is used in plastic (PE-PP-PVC-ABS) poliester , rubber, cosmetic and construction chemicals.
Zinc Stearate is used as a lubricant (external), mold release, filler, antifomer, heat and light stabilizer, water repellent, emulsifier.


Zinc stearate is used as a release agent for the manufacturing of rubber, polyurethane and polyester processing.
Zinc Stearate is a lubricant and thickening agent in cosmetic industry.
Zinc Stearate plays a vital role as an activator for rubber vulcanization.


Zinc Stearate acts as a phase transfer catalyst in the saponification of fats due to its lipophilic character.
Zinc Stearate is an active component in fanning powder, which is utilized to decrease the friction between cards.
Zinc Stearate is widely used as a release agent for the production of many kinds of objects rubber, poly urethane, poly ester processing system, powder metallurgy.


These applications exploit Zinc Stearate's "non-stick" properties .
In cosmetics, zinc stearate is a lubricant and thickening to improve texture.
Zinc Stearate is an "activator" for rubber vulcanization by sulfur and accelerators.


As discovered in the early days of vulcanization, zinc has a beneficial effect on the reaction of the sulfur with the polyolefin.
Zinc Stearate is a form of zinc that is highly soluble in the nonpolar medium of the poly olefins.
Being lipophilic, it functions as a phase transfer catalyst for the saponification of fats zinc stearate is used in cosmetic formulations to increase adhesive properties.


Zinc Stearate is also used as a coloring agent.
This is a mixture of the zinc salts of stearic and palmitic acids.
Zinc stearate is primarily used in pharmaceutical formulations as a lubricant in tablet and capsule manufacture at concentrations up to 1.5% w/w.


Zinc Stearate has also been used as a thickening and pacifying agent in cosmetic and pharmaceutical creams, and as a dusting powder.
Zinc Stearate is a fine textured powder that may find application as a binder and lubricant in pressed powders such as blushers, eyeliners, eye shadows, eyebrow pencils, face powders, foundations and other makeup preparations.


Zinc Stearate contains no electrolyte and has a hydrophobic effect.
Its main application areas are the plastics and rubber industry, where Zinc Stearate is used as a releasing agent and lubricant which can be easily incorporated.


Zinc Stearate is commonly used as a release agent, heat stabilizer and lubricant in the plastics, polyolefin, polystyrene and rubber industry.
Zinc Stearate is also used as a sanding additive in wood coatings (lacquers).
In cosmetics, zinc stearate is a lubricant and thickening to improve texture.


Zinc stearate has many unique properties, which is why it can be used in a wide range of industries.
For example, zinc stearate is used industrially as a release agent, lubricant and heat stabilizer for rubber and plastic manufacturers.
Zinc Stearateused as a sanding additive in wood coatings.


Zinc stearate also acts as a lubricant and thickener in cosmetics.
Thanks to its lubricating effects, water repellency, gelling capacity and non-stick texture, zinc stearate is highly versatile.


-Cosmetics:
Zinc Stearate acts as an anti-caking agent in powdered cosmetics.
Other uses of Zinc Stearate in cosmetics include as a lubricant, as well as a thickening agent for enhancing texture.


-CASE:
In CASE applications, Zinc Stearate serves as a lubricant aid in sanding sealers and as a flatting agent in paints and coatings.


-Metalworking Fluids:
Manufacturers of various types of metalworking fluid manufacturers make use of Zinc Stearate as an effective mold-release lubricant.
This is particularly beneficial in the manufacture of powdered metals where Zinc Stearate has minimal impact on sintering, which is the process of causing a powdered substance to coalesce into a solid or porous material via heating, but without liquefaction.


-Pharmaceuticals and Nutraceuticals:
Zinc Stearate facilitates mold release for tableting when used according to CFR 21 and FDA guidelines.


-Plastics and POLYMERS:
Zinc Stearate contributes toward effective use in the polymer industries as a heat stabiliser element.
For instance, take PVC stabilisers, which work for controlling the thermal degradation of Polyvinyl Chloride (PVC) compounds, which are further applied to the packaging of food and pharma products.


-RUBBER :
Zinc Stearate acts as an anti-tacking and anti-adhesive agent and is especially helpful in reducing adhesion between rubber surfaces and products made of rubber.
Zinc Stearate can also work as a mold release agent, dusting agent for rubber and a lubricant that prevents the rubber from clasping to the mold and also to itself.


-Pharmaceutical Industry:
Zinc Stearate’s major application in the pharmaceutical industry is in the manufacturing processes of tablets and capsules as a lubricant.
Nevertheless, occasionally Zinc Stearate can be observed in astringent solutions, mild antiseptics and in dental cement as well.
Additionally, Zinc Stearate can likewise be utilised as a particular soothing application for inflammatory skin diseases.
But there is one condition for these applications, Zinc Stearate must be of pharma grade and USP certified.


-CONCRETE:
In the construction industry, Zinc Stearate is exceedingly helpful as it acts as a waterproofing agent in refining the hydrophobicity of concrete and cement artillery.


-Processing Of Metal:
Zinc Stearate is an outstanding lubricant.
Zinc Stearate's a quality lubricant additive for bringing out metals such as wires, stainless steel, and aluminium and its alloys.
Some of the metals creating lubricants and surface finish lubricants are brought in with the addition of Zinc Stearate.


-PERSONAL CARE:
Zinc Stearate has a lot of uses, one such usage is that it can be used as a sticky or adhesive agent to create sealants and anti-skid adhesives for the generation of cosmetic formulations, and it encourages to acquire an anti-caking effect and can also act as an cosmetic colorant.


-Coating and Paint:
Zinc Stearate, is one of the most popular paints and coating materials, having multiple productive & efficient functions and properties.
In the paints, varnishing & lacquers industry, Zinc Stearate is utilised as a flatting and sanding agent to boost the coating film feel and also to prevent the softening of the film, which is caused by the rise in temperature at the time of mechanical polishing, and to paste or stick the sandpaper or grinding wheel to attain a matting outcome.
As a sanding agent, Zinc Stearate fills and improves the forming skills of the coatings of the wood as well as the lacquers.
In the generation of floor and wall coatings accompanied with other surface coatings, Zinc Stearate is utilised as an adhesive.
In all its coating applications, Zinc Stearate provides smoothness to the coating substance.


-Other Applications of Zinc Stearate:
Zinc Stearate can also be used as a nutrient supplement in food as a very small percentage, even less than 1%.
However, Zinc Stearate is mainly an industrial chemical, it is usually perceived as a safe component for the consumption of human beings, only when it is used according to the good manufacturing practice (GMP).


-Plastics:
Zinc Stearate is a highly effective pigment dispersion aid and lubricant in PVC, polyethylene and ABS production.
In SMC (sheet molding compound) applications, Zinc Stearate is used as a viscosity modifier and improves the surface of the finished good.
Zinc Stearate also acts as a scavenger for acidic residues in polyolefin manufacture and is used as a mold release agent and process lubricant in the production of polystyrene.


-Rubber:
Zinc Stearate serves as an internal lubricant in molded rubber production and as an external lubricant or dusting agent with excellent anti-block properties.
One of the most common Zinc Stearate uses in rubber manufacturing is as a release agent, as well as an activator for rubber vulcanization.


-Niche uses of Zinc Stearate:
Zinc Stearate is a component of some paints, imparting gloss.
As a chief ingredient in "fanning powder Zinc Stearate is used by magicians performing card manipulation to decrease the friction between playing cards.


-Applications of Zinc Stearate:
*PVC heat stabilizer
*ABS
*master batch
*lubricant
*powder metallurgy
*urea formaldehyde plastic


-The main areas of application are:
*Zinc Stearate in Vulcanized Rubber
*Zinc stearate is a vulcanization “activator” because zinc has a beneficial effect on the reaction of sulfur with polyolefin.
*Zinc stearate facilitates dispersion because it is very soluble in the non-polar part of polyolefins.
*Zinc Stearate acts as an antacid with polyolefins, thus contributing to color stability and preventing corrosion.


-Metallurgy:
Zinc Stearate is an ideal release agent for difficult parts, whether made of metal or plastic.
Zinc Stearate helps parts not to stick to the mold, therefore improves the finish.


-Paints and Varnishes:
*In its most refined form, zinc stearate has transparent properties and is therefore used in the manufacture of paints and varnishes.
*Zinc Stearate has great dispersibility and acts as a sealant for surface imperfections and as a thickener.
In addition, Zinc Stearate protects the paint from humidity due to its waterproofing properties.


-Pharmaceutical Applications
Zinc stearate is primarily used in pharmaceutical formulations as a lubricant in tablet and capsule manufacture at concentrations up to 1.5% w/w.
Zinc Stearate has also been used as a thickening and opacifying agent in cosmetic and pharmaceutical creams, and as a dusting powder.


-Sintering I Powder Metallurgy:
Zinc stearate is mixed as a lubricating additive with metal powder.
The proportion of the lubricants varies from 0.5% to 5.0% by weight.
In the press compaction stage, lubricants improve the flow and compressibility characteristics, while binders have the opposite effect.
Different amounts of additives influence the porosity and final properties of the material.
Zinc stearate has the advantage over other lubricants of providing zinc to the alloy, which is beneficial in some processes.
Finally, the additives volatilize from the “green” part in the sintering furnace after compaction in the press.


-Plastics and Color Additives:
Like other stearates it is used in the plastics industry:
*Lubricant and thermal stabilizer in PVC production
*Pigment dispersant in masterbatch
*In translucent impact applications, such as crystal polystyrene or other transparent polymers
*As a metallic release agent in polyurethane.


-Extruder Lubricants:
In order to improve productivity in extrusion production and lamination of plastics and metals, calcium stearate is added.
Zinc Stearate acts as a solid additive as well as lubricant by adding 0.3-1.0% calcium stearate to the mix in the feed hopper.
Zinc Stearate remains stable at high temperatures as well as improves the following points in manufacturing;
**Product homogeneity
**Hot spots
**Energy consumption
**Raw material savings


-VULCANIZING / RUBBER:
Zinc stearate is an “activator” for vulcanization because zinc has a beneficial effect on the reaction of sulphur with polyolefin.
Zinc stearate facilitates dispersion by being very soluble in the apolar region of polyolefins.
Zinc Stearate works as an antacid with polyolefins, contributing to colour stability and preventing corrosion.


-COSMETICS:
Zinc stearate is used as a lubricant, thickener, and to hold together the liquid and oily elements in cosmetics.
Zinc Stearate also improves the final appearance of the product.
Zinc Stearate usually appears in make-up formulations such as eyeliner, eye shadows, facemasks, lipsticks, face powders and foundation creams.
Zinc stearate does not cake; it flows very well and adds a silky touch to the mix.


-POWDER FOR PLAYING CARDS:
Zinc Stearate is widely used in the world of playing cards for the following purposes:
· Fans:
If the card deck is impregnated with a thin layer of zinc stearate, the cards will slide more easily.
Zinc Stearate remains transparent.
Zinc Stearate is used by magicians and casinos.

· Card deck cleaning:
Zinc stearate is impregnated in cotton to restore playing cards that may have been dirtied or marked by oil on the hands or through use.
Zinc stearate, due to its degree of fineness, is inserted into the scratches that the cards may have.
Zinc Stearate fills them and makes handling easier, as well as increasing speed when using the card decks.


-SEPARATING AGENT FOR METALURGY:
Zinc Stearate is an ideal separating agent for difficult machine parts, whether metal or plastic.
Zinc Stearate prevents the parts from adhering to the mould, leaving a better finish.


VARNISHES AND PAINTS:
In its finest form, zinc stearate has transparent properties and is used in the manufacture of varnishes and paints.
Zinc Stearate provides great dispersal ability and acts as a sealer for imperfections on the surface and as a thickener.
In addition, Zinc Stearate protects the paint from moisture due to its water-repelling properties.


-PLASTICS AND COLOUR ADDITIVES:
Like other stearates, Zinc Stearate has a wide number of applications in the plastics industry::
· Zinc Stearate is used as a lubricant and stabilizer in the production of PVC.
· As a pigment dispersant in Masterbatch.
· Due to its properties of transparency Zinc Stearate is used in impact glass applications, such as polystyrene for glass and other clear polymers.
· Zinc Stearate is used as a metal releasing agent in polyurethane.


-SINTERIZING – POWDER METALURGY:
Zinc stearate is mixed as a lubricant additive together with the metal powder.
The proportion of the lubricants varies from 0.5% to 5.0% by weight.
In the compacting phase in the press, the lubricants improve flow and compressibility characteristics; the binders have the opposite effect.
The different amount of the two additives influences the porosity and final properties of the material.
Zinc stearate has an advantage over other lubricants as it provides zinc for the alloy which is beneficial in certain processes.
Finally, the additives are volatilized from the part “in green” in the sintering oven after compacting in the press.


-LUBRICANT IN EXTRUDERS:
To improve productivity in production using extrusion and lamination of plastics and metals, calcium stearate is added.
Zinc Stearate acts as an additive and solid lubricant adding between 0.3 -1.0% of calcium stearate to the mixture in the feed hopper.
This remains stable at high temperatures and improves the following points in manufacturing:
· Product homogeneity
· Hot spots
· Energy consumption
· Saving of raw materials



FEATURES AND BENEFITS OF ZINC STEARATE:
*Anticaking / Anti-agglomeration Agent:
Zinc stearate is a white powder that is used as a lubricant in the manufacture of rubber and plastics.
Zinc Stearate can also be used as a food additive, such as in cheese and chocolate, to provide a protective layer.
Zinc stearate is an amphiphilic molecule and has been shown to exhibit surface effects on the nanoparticle size, shape, and surface charge.
The hydrophobic effect of zinc stearate causes it to form clusters with other molecules that are hydrophobic.
This cluster formation has been shown to alter transcriptional regulation in cells.
The use of zinc stearate has been associated with autoimmune diseases such as arthritis and bone cancer due to its interactions with drugs.
Zinc stearate is typically synthesized by heating anhydrous sodium or potassium carbonates with vegetable oils containing fatty acids (e.g., coconut oil) under controlled conditions of temperature and pressure.
Zinc stearate is a phase transfer catalyst for the saponification of fats.



HOW TO USE ZINC STEARATE
Zinc stearate isn’t an ingredient you can find on the shelves solo; rather, it’s used in products that have been formulated with it.
Zinc Stearate helps to prevent ingredients in powdered cosmetics from caking and it helps them to bind to the skin.
If your skin tolerates zinc stearate well, it can be used daily.



ZINC STEARATE IN COSMETICS:
*Zinc Stearate is used as a lubricant as well as a thickener and to hold the liquid and oily parts of the cosmetic together.
*In addition, Zinc Stearate improves the final appearance of the product.
Zinc Stearate usually appears in make-up formulations as well as eye lines, eyeshadows, mascaras, lipsticks, powders, and foundations.
*Zinc stearate does not harden, flows very well, and adds a silky feel to the mixture.



WHAT DOES ZINC STEARATE DO IN A FORMULATION?
*Anticaking
*Cosmetic colorant
*Viscosity controlling



PRODUCTION METHODS OF ZINC STEARATE:
An aqueous solution of zinc sulfate is added to sodium stearate solution to precipitate zinc stearate.
The zinc stearate is then washed with water and dried.
Zinc stearate may also be prepared from stearic acid and zinc chloride.



REACTIVITY PROFILE OF ZINC STEARATE:
Reactivity Profile
Zinc stearate is non-flammable but combustible. Incompatible with oxidizing agents, dilute acids.
Emits acrid smoke and fumes of ZnO when heated to decomposition.



BENEFITS OF ZINC STEARATE:
*Binds products:
Zinc stearate is often used as a soap or as an emulsifier or binder in cosmetics.

*Improves texture:
Zinc Stearate can give a product a bit of slip, which enhances the texture and make the application of a product more enjoyable.

*Adds color:
Zinc stearate can sometimes be used as a pigment or coloring agent.

*Generally safe:
Most skin types won’t have to worry about adverse reactions when using Zinc Stearate.
Though the ingredient is common enough, it’s typically used as part of the equation in a formula—Zinc Stearate isn’t the star of the ingredients list.



FEATURES OF ZINC STEARATE:
Zinc stearate has good thermal stability, initial stage stainability is small, it has good light stability and it has synergy effect with calcium stearate and barium stearate.
Zinc Stearate has foam effect and it can be used as foaming aid in foam products, it can be used as the lubricant of cosmetic face powder.



CHEMICAL PROPERTIES OF ZINC STEARATE:
Zinc stearate occurs as a fine, white, bulky, hydrophobic powder, free from grittiness and with a faint characteristic odor.
Zinc Stearate is white powder with fatty acid odour.
Zinc Stearate is a white, hydrophobic powder with a slight, characteristic odor.
Melting point of Zinc Stearate is 130°C.
Density of Zinc Stearate is 1.1 g cm-3.
Zinc Stearate is insoluble in water, ethyl alcohol and diethyl ether.
Zinc Stearate is soluble in acids.
Zinc Stearate is non-toxic.
In technical grades, the percentage of zinc may vary according to the intended use.
Products with less than the theoretical amount of zinc are more acidic.



MAIN BENEFITS OF ZINC STEARATE:
Binds or emulsifies products, improves the texture of products, can be used as a pigment or coloring agent



WHO SHOULD USE ZINC STEARATE:
Almost anyone who finds it in their skincare or makeup products



HOW OFTEN CAN YOU USE ZINC STEARATE:
Daily in a formulated product



ZINC STEARATE WORKS WELL WITH:
Most other ingredients



DON’T ZINC STEARATE USE WITH:
Zinc Stearate plays well with other ingredients, but since it’s a water-repellant, it may not work well with water-based products



APPEARANCE OF ZINC STEARATE:
Zinc stearate is a very fine, soft and colorless powder.
Zinc Stearate’s a high quality material with an exceptionally small particle size.
It doesn’t have a strong odor, though it’s possible for there to be a slight fatty acid scent because of the long-chain fatty acids.
Zinc stearates are soluble in aromatic compounds and chlorinated hydrocarbons when warmed, but they are insoluble in alcohol and ethers.



THE INDUSTRIES THAT BENEFIT FROM USING ZINC STEARATE:
-Rubber
-Plastics/Polymers
-Masterbatch
-Paint and Coating
-Cosmetics
-Pharmaceutical
-Paper
-Concrete



PHYSICAL and CHEMICAL PROPERTIES of ZINC STEARATE:
Chemical formula: C36H70O4Zn
Molar mass: 632.33 g·mol−1
Appearance: soft, white powder
Odor: slight, characteristic[1]
Density: 1.095 g/cm3, solid
Melting point: 120 to 130 °C (248 to 266 °F; 393 to 403 K)
Boiling point: decomposes
Solubility in water: insoluble
Solubility in Ethanol: insoluble
Solubility in ether: insoluble
Solubility in benzene: slightly soluble
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Melting point: 128-130 °C (lit.)
Boiling point: 240℃[at 101 325 Pa]
Density: 1.095g/cm3
vapor pressure: 0Pa at 25℃
Flash point: 180℃
storage temp.: Inert atmosphere,Room Temperature
solubility: alcohol: insoluble(lit.)
form: Powder
color: White
Odor: wh. powd., faint char. odor
Water Solubility: Insoluble
Merck: 14,10158
BRN: 3919706
Exposure limits ACGIH: TWA 10 mg/m3; TWA 3 mg/m3
OSHA: TWA 15 mg/m3; TWA 5 mg/m3
NIOSH: TWA 10 mg/m3; TWA 5 mg/m3
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: 4.64 at 25℃

EC Number: 209-151-9
ICSC Number: 0987
RTECS Number: ZH5200000
UN Number: 3077 UNIIH92E6QA4FV
IUPAC Name: Zinc;octadecanoate
Category: Heterocyclic Organic Compound
Molecular Formula: C36H70ZnO4
Molecular Weight: 632.35
Rotatable Bond Count: 30
Exact Mass: 630.457g/mol
Monoisotopic Mass: 630.457g/mol
Topological Polar Surface Area: 80.3A^2
Heavy Atom Count: 41
Complexity: 196
Covalently-Bonded Unit Count: 3
Physical State: Solid
Appearance: White powder
Zinc assay: 10.3~11.3%
Free acid: ≤1.0%
Loss on drying: ≤1.0%
Melting point: 120~125℃
Appearance: Fine, white powder
Zinc Content: 10.8 % ±0.5
Free Fatty Acid: 0.5 % Max.
Melting Point: 120°C ± 5

Melting point: °C 120
Boiling point: °C 240
Density g/ cm³: 1.1 20 °C
Solubility: µg/L 4.6 25 °C, soluble with water
steam pressure: Pa 0 25 °C
LogP: 4.64 25 °C
flash point: °C 277 open cup
Autoignition temperature: °C 420
pKa: 0 37 °C
Compound Formula: C36H70O4Zn
Molecular Weight: 632.33
Appearance: White Powder
Melting Point: 130 °C
Boiling Point: N/A
Density: 1.095 g/cm3
Solubility in H2O: N/A
Exact Mass: 630.456553
Monoisotopic Mass: 630.456553

Colour: White
Water content: % 0/5
Appearance: Powder
Free fatty acid %: 0/5-1
Melting Point ℃: 125
Ash content %: 13 Max
Bulk Density g/l: 350
Application: Plastic - rubber
Melting Point: 130°C
Color: White
Quantity: 250 g
Merck Index: 14,10158
Solubility Information: Insoluble in water,alcohol and ether;
Soluble in benzeneSoluble in acids,aromatic and chlorinated hydrocarbons;
Insoluble in water,alcohol and ether.
Formula Weight: 632.48
Physical Form: Powder
Chemical Name or Material: Zinc stearate



FIRST AID MEASURES of ZINC STEARATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC STEARATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC STEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC STEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC STEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ZINC STEARATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available



SYNONYMS:
zinc octadecanoate
zinc distearate
CB9677027
Synpro stearate
ZINC OCTADECANOATE
Talculin Z
Zinkstearat
stavinorzn-e
stearatedezinc
Coad
Mathe
Hytech
zinc distearate
zinc octadecanoate

ZINC SULFATE
Zinc Sulfate is an inorganic salt.
Zinc sulfate is an inorganic compound with the molecular formula ZnSO4.
The nutritional supplement is Zinc Sulfate.
Zinc sulfate has been traditionally referred to as white vitriol.


CAS Number: 7733-02-0
7446-19-7 (monohydrate)
13986-24-8 (hexahydrate)
7446-20-0 (heptahydrate)
EC Number: 231-793-3
Molecular Formula: ZnSO4 or O4SZn


Zinc sulfate is also known as Zincate, Sulfate of Zinc (1:1).
Zinc sulfate describes a family of inorganic compounds with the formula ZnSO4(H2O)x.
The most common form of Zinc sulfate includes water of crystallization as the heptahydrate, with the formula ZnSO4·7H2O.
Zinc sulfate was historically known as "white vitriol".


Zinc sulfate and its hydrates are colourless solids.
Zinc sulfate is a potent inhibitor of sweetness perception for most sweet-tasting substances.
Zinc sulfate has the formula ZnSO4 as well as any three hydrates.
Zinc sulfate was historically known as "white vitriol".


All various forms are colorless solids.
The heptahydrate form is frequently encountered.
Zinc sulfate is a mineral used to treat or prevent low levels of zinc.
Zinc sulfate is used as a malting/fermenting aid and as a nutrient supplement Zinc sulfate (ZnSO4) is a colorless crystalline, water-soluble chemical compound.


The hydrated form, ZnSO4*7H2O, the mineral goslarite, was historically known as white vitriol and can be prepared by reacting zinc with aqueous sulfuric acid.
Zinc sulfate may also be prepared by adding solid zinc to a copper(II) sulfate solution.
Zinc sulfate has been shown to exhibit antibiotic and anti-spectic functions (A7766, A7767).


Zinc sulfate belongs to the family of Transition Metal Sulfates.
These are inorganic compounds in which the largest oxoanion is sulfate, and in which the heaviest atom not in an oxoanion is a transition metal.
Anhydrous zinc sulfate is a colorless crystalline solid.
Zinc sulfate is also obtained as a hexahydrate, ZnSO4.6H2O, and as a heptahydrate ZnSO4.7H2O.


All forms are soluble in water.
All are noncombustible.
Zinc sulfate is a metal sulfate compound having zinc(2+) as the counterion.
Zinc sulfate has a role as a fertilizer.


Zinc sulfate is a metal sulfate and a zinc molecular entity.
Zinc sulfate contains a zinc(2+).
Zinc sulfate is a basic mineral for the human body which boosts metabolism and can be consumed regularly as part of a healthy diet.
Zinc sulfate is a basic mineral for the human body.


Zinc sulfate boosts metabolism and can be consumed regularly as part of a healthy diet.
Herbal Goodness Zinc Sulfate Liquid Supplement can boost your immune system and promote healthy digestion.
Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Zinc sulfate is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.


Zinc Sulfate is a chemical compound with the formula of ZnSO4, and ZnSO4•7H2O in heptahydrate form.
The Heptahydrate form ZnSO4•7H2O is the most common form of Zinc Sulfate.
Zinc Sulfate appears as a colorless, odorless powder.
Zinc sulphate is highly soluble zinc salt, with easy disassociation in the gut and good bioavailability.


Zinc sulfate is a chemical compound created from Zinc and sulfuric acid.
Zinc sulfate is listed on the List of Essential Medicines of the World Health Organization.
Zinc sulfate is an inorganic compound.
As the already mentioned formula of zinc sulfate ZnSO4.


The most popular form of Zinc sulfate, with the formula ZnSO4•7H2O, contains crystallization water as the heptahydrate.
"Historically, Zinc sulfate was known as "white vitriol".
Zinc sulfate and its hydrates are solids that are colorless.
Zinc sulphate is a supplement to prevent or treat deficiency (deficiency) of zinc or zinc.


In addition, Zinc sulfate is also used in the treatment of acute diarrhea.
Zinc sulphate is one of the dosage forms of zinc supplements.
In 220 mg of zinc sulfate, contained 50 mg of elemental zinc.
Zinc sulfate supplements should be taken 1–2 hours after eating.


*Antimicrobial :
Zinc sulfate helps slowing the growth of micro-organisms on the skin and counteracts the development of microbes
*Antiplaque :
Zinc sulfate helps prevent plaque formation
*Astringent :
Zinc sulfate helps tighten skin pores
*Oral care/hygiene agent :
Zinc sulfate provides cosmetic effects to the oral cavity (cleaning, deodorization and protection)



USES and APPLICATIONS of ZINC SULFATE:
Zinc sulfate can be used to supplement zinc in the brewing process.
Zinc is a necessary nutrient for optimal yeast health and performance, although it is not a necessary supplement for low-gravity beers, as the grains commonly used in brewing already provide adequate zinc.
Zinc sulfate is a more common practice when pushing yeast to its limit by increasing alcohol content beyond its comfort zone.


Zinc sulfate is used in the production of rayon, as a feed supplement, and as a fertilizer ingredient.
Zinc sulfate is a combination of sulfur and zinc.
This is an herbicide commonly used for algae control.
The toxicity of zinc sulfate depends on the amount of zinc in the product.


Zinc sulfate is an inorganic compound and nutritional supplement.
Additionally, Zinc sulfate is used to treat zinc deficiency and prevent high-risk conditions.
Zinc sulfate is a drug used to replenish low levels of zinc or prevent zinc deficiency, or test for zinc deficiency.
Zinc sulphate in particular is used in the treatment of Wilson's disease (a condition of excess copper in the body).


There are also reports of Zinc sulfate being used to enhance wound healing.
Zinc sulfate is used primarily as an antimicrobial agent in bath products, dental care and hygiene products.
Zinc Sulfate has many uses including medicinal astringents, production of rayon, uses in electroplating, animal feeds, toothpaste, acne treatments, and fertilizers.


Zinc sulfate is a vitamin and mineral drug that treats and prevents zinc deficiency in the body.
Zinc sulfate is a drug belonging to the group of vitamins and minerals.
Zinc sulfate is used to treat zinc deficiency and to avoid the disease in those at high risk as a dietary supplement.


-Zinc sulfate medicine is prescribed by doctors to use in the following cases:
*Diarrhea patient.
*People with zinc deficiency. Immunocompromised people. *People who often lose hair, need to improve their wounds or maintain their taste buds.


-Cosmetic Uses of Zinc sulfate:
*antimicrobial agents
*antiplaque agents
*astringents
*oral care agents


-Medicine uses of Zinc sulfate:
Zinc sulfate is used as a dietary supplement to treat zinc deficiency and to prevent the condition in those at high risk.
Zinc sulfate is also used together with oral rehydration therapy (ORT) and an astringent.


-Manufacturing uses of Zinc sulfate:
The main application of Zinc sulfate is as a coagulant in the production of rayon.
Zinc sulfate is also a precursor to the pigment lithopone.
Zinc sulfate is also used as an electrolyte for zinc electroplating, as a mordant in dyeing, and as a preservative for skins and leather.


-Nutrition:
Zinc sulfate is used to supply zinc in animal feeds, fertilizers, toothpaste, and agricultural sprays.
Zinc sulfate, like many zinc compounds, can be used to control moss growth on roofs.


-Usage areas of Zinc sulfate:
*In Agricultural Sector
*In the Chemical Industry
*Pigment, Zinc analysis, Pharmaceutical Industry
*In mining ore
*Synthetic Fiber Industry, Beer industry
*Paint, Leather, Yeast industry
*Feed industry, Zinc fertilizer production
*Zinc sulfate increases the amount of product taken per unit area.
*Zinc sulfate regulates soil pH.
*Zinc sulfate prevents yellowing of leaves, premature shedding and shrinkage.
*Zinc sulfate increases the plant's resistance to cold.
Increases fruit holding in fruit trees.
*Zinc sulfate improves the appearance of the fruit and prevents deformation.
*Zinc sulfate increases the number of shoots, prevents stunting.
*Zinc sulfate increases the water holding capacity and enables the plant to be affected by drought later.
Increases the length and stem thickness of grains.
*Zinc sulfate prevents the yellowing of grass in meadows and pastures, grows fast and provides abundant grass formation.



PROPERTIES OF ZINC SULFATE:
Zinc Sulfate has a white powder look and is odorless.
Zinc Sulfate, which is soluble in water, is non-combustible.
During decomposition, Zinc sulfate releases poisonous gases of zinc oxide and sulfur oxides.
Zinc sulfate is commonly used in zinc deficiency prevention and treatment.



WHAT DOES ZINC SULFATE DO IN A FORMULATION?
*Antimicrobial
*Antiplaque
*Astringent
*Oral care



HOW TO USE ZINC SULFATE:
Take Zinc sulfate by mouth as directed by your doctor or the product package.
Take Zinc sulfate 1 hour before or 2 hours after meals.
Zinc sulfate may be taken with food if it upsets your stomach.
Zinc sulfate is used this product regularly in order to get the most benefit from it.
To help you remember, use Zinc sulfate at the same time(s) each day.



MAKING ZINC SULFATE:
Zinc sulfate is a complex fertiliser.
Zinc sulfate is a source of the micronutrient zinc and the
secondary nutrient sulfur.
However, Zinc sulfate is as a source of zinc that it is important.
Zinc sulfate is produced by reacting zinc carbonate with sulfuric acid:
ZnCO3(s) + H2SO4(aq)  ZnSO4(aq) + H2O(l) + CO2(g)
Zinc sulfate used for pharmaceutical preparations is made from the reaction of sulfuric acid with
high purity zinc oxide:
ZnO(s) + H2SO4(aq)  ZnSO4(aq) + H2O(l)
Zinc sulfate crystallises from aqueous solution as a heptahydrate, zinc sulfate-7-water, ZnSO4.7H2O.
You can make zinc sulfate-7-water in the laboratory by reacting zinc carbonate with dilute sulfuric
acid.



HEALTH BENEFITS OF ZINC SULFATE:
*IMMUNE BOOSTER:
Zinc sulfate performs a vital role in your immune system, boosts metabolism, and, supports digestion.
Zinc sulfate may also help prevent zinc deficiency and reduce the severity of acne.

*FAST ABSORPTION:
Zinc sulfate will not only be absorbed into your body faster, but it is also more soluble than capsules so that you will get more of the vitamin into your system as well.

*SUITABLE FOR VEGANS AND VEGETARIANS :
Zinc sulfate is Vegan, contains non-GMO ingredients, Gluten-Free, and does NOT contain any Yeast, Wheat, Milk or Milk Derivatives, Lactose, Sugar, Soy, Artificial Colors, and Flavors.

*SUPPORTS METABOLISM:
Zinc Sulfate assists the digestive system to function properly leaving you in great shape.

*DELICIOUS TASTING:
This glycerin-based extract tastes great.
No sugar has been added.



WHAT IS ZINC SULFATE USED FOR?
Zinc Sulfate can be incorporated into a healthy diet to help boost the immune system and aid digestion.



PRODUCTION, REACTIONS, AND STRUCTURE OF ZINC SULFATE:
Specific reactions include the reaction of the metal with aqueous sulfuric acid:
Zn + H2SO4 + 7 H2O → ZnSO4·7H2O + H2
Pharmaceutical-grade zinc sulfate is produced by treating high-purity zinc oxide with sulfuric acid:

ZnO + H2SO4 + 6 H2O → ZnSO4·7H2O
In aqueous solution, all forms of zinc sulfate behave identically.
These aqueous solutions consist of the metal aquo complex [Zn(H2O)6]2+ and SO2−4 ions.
Barium sulfate forms when these solutions are treated with solutions of barium ions:

ZnSO4 + BaCl2 → BaSO4 + ZnCl2
With a reduction potential of −0.76 V, zinc(II) reduces only with difficulty.

When heated above 680 °C, zinc sulfate decomposes into sulfur dioxide gas and zinc oxide fume, both of which are hazardous.
The heptahydrate is isostructural with ferrous sulfate heptahydrate.
The solid consists of [Zn(H2O)6]2+ ions interacting with sulfate and one water of crystallization by hydrogen bonds.
Anhydrous zinc sulfate is isomorphous with anhydrous copper(II) sulfate.
Zinc sulfate exists as the mineral zincosite.
A monohydrate is known.
The hexahydrate is also recognized.



MINERALS:
As a mineral, ZnSO4•7H2O is known as goslarite.
Zinc sulfate occurs as several other minor minerals, such as zincmelanterite, (Zn,Cu,Fe)SO4·7H2O (structurally different from goslarite).
Lower hydrates of zinc sulfate are rarely found in nature: (Zn,Fe)SO4·6H2O (bianchite), (Zn,Mg)SO4·4H2O (boyleite), and (Zn,Mn)SO4·H2O (gunningite).



PHYSICAL and CHEMICAL PROPERTIES of ZINC SULFATE:
Chemical formula: ZnSO4
Molar mass: 161.44[1] g/mol (anhydrous)
179.47 g/mol (monohydrate)
287.53 g/mol (heptahydrate)
Appearance: white powder
Odor: odorless
Density: 3.54 g/cm3 (anhydrous)
2.072 g/cm3 (hexahydrate)
Melting point: 680 °C (1,256 °F; 953 K) decomposes (anhydrous)
100 °C (heptahydrate)
70 °C, decomposes (hexahydrate)
Boiling point: 740 °C (1,360 °F; 1,010 K) (anhydrous)
280 °C, decomposes (heptahydrate)
Solubility in water: 57.7 g/100 mL, anhydrous (20 °C) (In aqueous solutions with a pH < 5)[2]

Solubility: alcohols
Magnetic susceptibility (χ): −45.0·10−6 cm3/mol
Refractive index (nD): 1.658 (anhydrous), 1.4357 (heptahydrate)
Std molar entropy (S⦵298): 120 J·mol−1·K−1[3]
Std enthalpy of formation (ΔfH⦵298): −983 kJ·mol−1[3]
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 100.00 °C. @ 760.00 mm Hg
Boiling Point: 330.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000034 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.031 (est)
Soluble in: water, 57.7 g/100 g water at 25 °C (exp)

Boiling Point/Range: No data available
Color: Colorless
Concentration: 0.1 M
Density: No data available
Flashpoint: Not applicable
Form: Liquid
Grade: Volumetric Titration
Incompatible Materials: Alkalis
Lower Explosion Limit: Not applicable
Melting Point/Range: No data available
Partition Coefficient: No data available
Solubility in Water: Completely miscible
Upper Explosion Limit: Not applicable
Vapor Pressure: No data available
Viscosity: No data available
pH-Value: No data available
Product Line: Volumetric
Storage Temperature: Ambient


Molecular Weight: 161.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 159.880871
Monoisotopic Mass: 159.880871
Topological Polar Surface Area: 88.6 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Physical state: clear, liquid
Color: colorless
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: Not applicable
Decomposition temperature: No data available
pH: 3,5 - 4,5
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility at 20 °C soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,310 g/cm3
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available


FIRST AID MEASURES of ZINC SULFATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC SULFATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.



FIRE FIGHTING MEASURES of ZINC SULFATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC SULFATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC SULFATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage class:
Storage class (TRGS 510): 12:
Non Combustible Liquids



STABILITY and REACTIVITY of ZINC SULFATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Zinc sulfate
White vitriol
Goslarite
Zinc sulfate
Zinc sulphate
7733-02-0
Zinc sulfate anhydrous
Zincate
Zinc sulfate (1:1)
ZnSO4
Sulfuric acid, zinc salt (1:1)
Sulfate de zinc
zinc(II) sulfate
Zinc sulphate anhydrous
Zinc sulfate, anhydrous
Zinc sulphate, anhydrous
Zinc sulfate (anhydrous)
Zinc sulfate hydrate
0J6Z13X3WO
CHEBI:35176
NSC-32677
NSC-135806
Medizinc
Optised
Orazinc
Solvezinc
Zinklet
Neozin
Visine-ac
Zinci Sulfas
Prefrin-Z
Zincum Sulfuricum
Zink-Gro
Zinc vitriol (VAN)
Caswell No. 927
White vitriol (VAN)
Zincsulphate
Salvazinc
zinc;sulfate
NU-Z
Sulfuric acid, zinc salt
Zinc-200
CCRIS 3664
Sulfuric acid zinc salt (VAN)
HSDB 1063
EINECS 231-793-3
NSC 32677
EPA Pesticide Chemical Code 089001
NSC 135806
UNII-0J6Z13X3WO
AI3-03967
Sulfato de cinc
zinc(II)sulfate
Sulfato de zinco
Solfato di Zinco
Zinc (as sulfate)
zinc(2+) sulfate
MFCD00011302
Zinc (as sulphate)
Zinc sulphate hydrate
Zinci sulfas monohydrate
Zinc Suflate Monohydrate
Zinci sulfas heptahydrate
ZINC SULFATE [MI]
EC 231-793-3
ZINC SULFATE [HSDB]
CHEMBL1200929
DTXSID2040315
Zinc sulfate, unspecified hydrate
AKOS025295737
DB09322
Q204954
J-010404

ZINC SULPHATE
Zinc Sulphate is a metal sulfate compound having zinc(2+) as the counterion.
ZnSO4 is an inorganic compound with the chemical name Zinc Sulphate.


CAS Number: 7733-02-0
7446-19-7 (monohydrate)
13986-24-8 (hexahydrate)
7446-20-0 (heptahydrate)
EC Number: 231-793-3
Chemical formula: ZnSO4



Zinc sulfate, White vitriol, Goslarite, Zinc sulfate, 7733-02-0, Zinc sulphate, Zinc sulfate anhydrous, Zincate, White vitriol, zinc(II) sulfate, Zincomed, Optraex, Zinc vitriol, OP-Thal-zin, Zinc sulfate (1:1), Bufopto zinc sulfate, ZnSO4, Sulfuric acid, zinc salt (1:1), Zinc sulphate anhydrous, Sulfate de zinc, Zinc sulfate, anhydrous, Zinc sulphate, anhydrous, Zinc sulfate (anhydrous), Zincfrin, Zinc (as sulfate), zinc(2+) sulfate, Zinc (as sulphate), 0J6Z13X3WO, Zinc sulphate hydrate, CHEBI:35176, NSC-32677, NSC-135806, DTXSID2040315, Zinc sulfate, unspecified hydrate, Medizinc, Optised, Orazinc,
Solvezinc, Zinklet, Neozin, Visine-ac, Zinci Sulfas, Prefrin-Z, Zincum Sulfuricum, Zink-Gro, Zinc vitriol (VAN), Caswell No. 927, White vitriol (VAN), Zincsulphate, Salvazinc, zinc;sulfate, NU-Z, Sulfuric acid, zinc salt, Zinc-200, Sulfate, Zinc, CCRIS 3664, Sulfuric acid zinc salt (VAN), HSDB 1063, EINECS 231-793-3, NSC 32677, EPA Pesticide Chemical Code 089001, NSC 135806, UNII-0J6Z13X3WO, AI3-03967, Sulfato de cinc, zinc(II)sulfate, Caswell No 927, O4SZn, HONNY FRESH 10P, ZINC SULFATE (II), ZINC SULFATE [MI], EC 231-793-3, ZINC SULFATE [HSDB], ZINC SULFATE (MART.), ZINC SULFATE (USP-RS), 89DS0H96TB, CHEMBL1200929, DTXCID0020315, NWONKYPBYAMBJT-UHFFFAOYSA-L, Zinc Sulfate (Solution in Water), ZINC SULFATE (USP IMPURITY), EPA Pesticide Chemical Code 08901, AKOS025295737, DB09322, NS00076230, Q204954, J-010404,



Zinc Sulphate describes a family of inorganic compounds with the formula ZnSO4(H2O)x.
All are colorless solids.
The most common form includes water of crystallization as the heptahydrate, with the formula ZnSO4·7H2O.


As early as the 16th century Zinc Sulphate was prepared on the large scale, and was historically known as "white vitriol" (the name was used, for example, in 1620s by the collective writing under the pseudonym of Basil Valentine).
Zinc Sulphate and its hydrates are colourless solids.


Zinc Sulphate (ZnSO4) is a colorless crystalline, water-soluble chemical compound.
The hydrated form, ZnSO4*7H2O, the mineral goslarite, was historically known as white vitriol and can be prepared by reacting zinc with aqueous sulfuric acid.


Zinc Sulphate may also be prepared by adding solid zinc to a copper(II) sulfate solution.
Zinc Sulphate has been shown to exhibit antibiotic and anti-spectic functions (A7766, A7767).
Zinc Sulphate belongs to the family of Transition Metal Sulfates.


These are inorganic compounds in which the largest oxoanion is sulfate, and in which the heaviest atom not in an oxoanion is a transition metal.
Zinc Sulphate is a combination of sulfur and zinc.
Zinc Sulphate is an herbicide typically used for moss control.


Zinc is an essential mineral for human, animal, and plant nutrition.
Zinc can be found naturally in the environment, foods, and water.
Anhydrous Zinc Sulphate is a colorless crystalline solid.


Zinc Sulphate is also obtained as a hexahydrate, ZnSO4.6H2O, and as a heptahydrate ZnSO4.7H2O.
All forms are soluble in water.
All are noncombustible.


Immediate steps should be taken to limit its spread to the environment.
Zinc Sulphate is a metal sulfate compound having zinc(2+) as the counterion.
Zinc Sulphate has a role as a fertilizer.


Zinc Sulphate is a metal sulfate and a zinc molecular entity.
Zinc Sulphate contains a zinc(2+).
Zinc Sulphate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".


Zinc Sulphate is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.
Zinc Sulphate is a salt of the essential trace metal zinc.
Zinc is involved in tissue repair and is an important constituent of some proteins, including those involved in taste and smell.


Zinc Sulphate supplementation may prevent radiation-induced aguesia. (NCI04)
Zinc Sulphate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Zinc Sulphate is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.


ZnSO4 is an inorganic compound with the chemical name Zinc Sulphate.
Zinc Sulphate is a dietary supplement.
Zinc Sulphate was historically called white vitriol.


Zinc Sulphate is also known as Zincate, Zinc Sulphate (1:1).
Zinc Sulphate is listed on the World Health Organization’s List of Essential Medicines.
Zinc Sulphate is odourless and has a white powder appearance.


Zinc Sulphate is non-combustible and soluble in water.
Zinc is a naturally occurring mineral.
Zinc is important for growth and for the development and health of body tissues.


Zinc Sulphate is a combination of sulfur and zinc.
Zinc Sulphate is an herbicide commonly used for moss control.
Zinc is a mineral necessary for human, animal and plant nutrition.


Zinc is found in the natural environment, foods and water.
Zinc Sulphate is an inorganic compound and dietary supplement.
Zinc Sulphate has the formula ZnSO4 as well as any of its three hydrates.


Zinc Sulphate was historically known as "white vitriol".
All various forms are colorless solids.
The heptahydrate form is frequently encountered.


Zinc sulphate is a form of zinc that is soluble in in water.
Zinc Sulphate contains 22% soluble zinc in water.
Zinc sulphate has a white crystalline appearance.


The importance of zinc in agricultural production is quite high.
Although the rate of absorbable zinc varies according to the regions in our country’s soil, it is generally below the desired level.
Zinc deficiency prevents the plant from developing sufficiently and, as a result, causing less fruit.


Zinc sulphate fertilization increases plant efficiency and ensures that all the fruits are the same size and look alive.
Zinc Sulphate is a metal sulfate compound containing zinc (2+) as a counter ion.
Zinc Sulphate acts as fertilizer.


Zinc Sulphate is a metal sulfate and a zinc molecular entity.
Zinc Sulphate contains a zinc (2+).
Anhydrous Zinc Sulphate is a colorless crystalline solid.


Zinc is an essential mineral in people as well as other animals.
The medical use of Zinc Sulphate began as early as the 1600s.
Zinc Sulphate is on the World Health Organization's List of Essential Medicines.
Zinc Sulphate is available as a generic medication and over the counter.



USES and APPLICATIONS of ZINC SULPHATE:
Medically it is used along with oral rehydration therapy.
Zinc Sulphate acts as a coagulant in the production of rayon.
Zinc Sulphate is used as a preservative for leathers.


Zinc Sulphate is used in zinc electroplating as an electrolyte.
Zinc Sulphate is used as a mordant in dyeing.
Zinc Sulphate is used in the brewing process as a zinc supplement.


Zinc Sulphate is used as an astringent in eye drops and lotions.
Zinc Sulphate is used to treat acne.
You can take Zinc Sulphate with food if you are suffering from stomach upset.


Zinc Sulphate is used to treat and to prevent zinc deficiency and it also helps in the immune system function.
Zinc Sulphate is used in the production of rayon, as a feed supplement, and as a fertilizer ingredient.
Zinc Sulphate is used as a malting/fermenting aid and as a nutrient supplement.


Zinc Sulphate is a compound given in the treatment of conditions associated with zinc deficiency such as acrodermatitis enteropathica.
Externally, Zinc Sulphate is used as an astringent in lotions and eye drops.
Zinc Sulphate may also be used for purposes not listed in this medication guide.


Zinc Sulphate is widely used in the prevention and treatment of zinc deficiency.
Zinc Sulphate is used in the Agriculture Sector.
Zinc Sulphate is used in the Chemical Industry.


Zinc Sulphate is used Pigment, Zinc analysis, Pharmaceutical Industry.
Zinc Sulphate is used in ore extraction.
Zinc Sulphate is used synthetic Fiber Industry, Beer industry.


Zinc Sulphate is used paint, Leather, Yeast sector.
Zinc Sulphate is used feed industry, Zinc fertilizer production.
Zinc Sulphate increases the amount of product taken per unit area.


Zinc Sulphate regulates soil pH.
Zinc Sulphate prevents yellowing, premature shedding and shrinkage of leaves.
Zinc Sulphate increases the plant's resistance to cold.


Zinc Sulphate increases fruit retention in fruit trees.
Zinc Sulphate improves the appearance of the fruit and prevents deformation.
Zinc Sulphate increases the number of shoots and prevents stunting.


Zinc Sulphate increases water retention capacity and ensures that the plant is affected by drought later.
Zinc Sulphate increases the length and stalk thickness of grains.
Zinc Sulphate prevents the grass from turning yellow in meadows and pastures, grows quickly and ensures abundant grass formation.


Zinc Sulphate is used in the following products: cosmetics and personal care products, washing and cleaning products, fertilizers, pharmaceuticals, biocides (eg disinfectants, pest control products), metal surface treatment products, lubricants and greases, metalworking fluids and polymers.
Zinc Sulphate is used in machine wash fluids/detergents, automotive care products, paints, coatings or adhesives, fragrances and air fresheners, hydraulic fluids in automotive suspension, lubricants in engine oil and brake fluids.


Additionally, Zinc Sulphate is used to treat zinc deficiency and prevent high-risk conditions.
Zinc Sulphate is used medically as a dietary supplement.
Specifically Zinc Sulphate is used to treat zinc deficiency and to prevent the condition in those at high risk.


Zinc Sulphate includes use together with oral rehydration therapy for children who have diarrhea.
Zinc Sulphate may be taken by mouth or by injection into a vein.
Zinc Sulphate prevents yellowing, premature shedding and shrinkage on the leaves of plants.


In fruit trees, Zinc Sulphate increases the number of shoots and fruit set.
Zinc sulphate prevents deformities in fruits.
By arranging the pH level of the soil, zinc sulphate increases the plant's water holding capacity and product productivity.


Zinc sulphate plays a crucial role in raising the market value of the products.
Zinc Sulphate is used for the elimination of zinc deficiency in plants and inhibits the growth of weeds in the fields.
Zinc Sulphate is used as a feed additive in animal foods


-Manufacturing uses of Zinc Sulphate:
Zinc Sulphate is used the main application of the heptahydrate is as a coagulant in the production of rayon.
Zinc Sulphate is also a precursor to the pigment lithopone.
Zinc Sulphate is also used as an electrolyte for zinc electroplating, as a mordant in dyeing, and as a preservative for skins and leather.


-Nutrition uses of Zinc Sulphate:
Zinc Sulphate is used to supply zinc in animal feeds, fertilizers, toothpaste, and agricultural sprays.
Zinc Sulphate, like many zinc compounds, can be used to control moss growth on roofs.

Zinc Sulphate can be used to supplement zinc in the brewing process.
Zinc is a necessary nutrient for optimal yeast health and performance, although it is not a necessary supplement for low-gravity beers, as the grains commonly used in brewing already provide adequate zinc.

It is a more common practice when pushing yeast to their limit by increasing alcohol content beyond their comfort zone.
Before modern stainless steel, brew Kettles, fermenting vessels and after wood, zinc was slowly leached by the use of copper kettles.
A modern copper immersion chiller is speculated to provide trace amounts of zinc; thus care must be taken when adding supplemental zinc so as not to cause excess.

Side effects include "...increased acetaldehyde and fusel alcohol production due to high yeast growth when zinc concentrations exceed 5 ppm.
Excess zinc can also cause soapy or goaty flavors."
Zinc Sulphate is a potent inhibitor of sweetness perception for most sweet-tasting substances.


-Medicine uses of Zinc Sulphate:
Zinc Sulphate is used as a dietary supplement to treat zinc deficiency and to prevent the condition in those at high risk.
Zinc Sulphate is also used together with oral rehydration therapy (ORT) and an astringent.


-Medical uses of Zinc Sulphate:
The use of Zinc Sulphate supplements together with oral rehydration therapy decreases the number of bowel movements and the time until the diarrhea stops.
Zinc Sulphate's use in this situation is recommended by the World Health Organization.
There is some evidence zinc is effective in reducing hepatic and neurological symptoms of Wilson's disease.
Zinc Sulphate is also an important part of parenteral nutrition.



BENEFITS OF ZINC SULPHATE:
-Zinc Sulphate improved yeast growth
-Faster Fermentations
-Reduction of sulphur characteristics
-Concentrated product—economical in use



BENEFITS OF IT IN PLANTS:
*Unit increases the amount of product received in the area.
*Zinc Sulphate regulates the Ph of soil.
*prevent early spillage and shrinkage in the leaves
*Zinc Sulphate increases the resistance of the plant against cold.
*Increase fruit retention in fruit trees.
*Beautifies the appearance of the fruit, preventing deformity.
*Zinc Sulphate increases the number of exiles, prevents stunning.
*Zinc Sulphate increases the water holding capacity and allows the plant to be affected later than the drought.
*Zinc Sulphate increases the neck and handle thickness of cereals.
*Zinc Sulphate prevents yellowing of grasses in meadows and meadows, expands rapidly and provides plenty of grass.



THE IMPORTANCE OF ZINC IN NUTRITION OF ANIMALS:
Animals that are fed with zinc-deficient pastures and grains that are grazed in meadows or that lack zinc are not able to take enough zinc; and as a result;
*Loss of appetite, moodiness, slowdown in growth
*Weakness in muscle development
*Weight loss, Hair loss
*Foot swelling
*Immune system weakness against diseases
*Inflammation around the nose and mouth
*Decreased fertility in the female animals
*Excessive bleeding at birth
*Deterioration of testicles and decrease in sperm formation in male animals
*Drop in milk yield.



HOW TO USE ZINC SULPHATE:
Take Zinc Sulphate by mouth as directed by your doctor or the product package.
Take Zinc Sulphate 1 hour before or 2 hours after meals.
Zinc Sulphate may be taken with food if it upsets your stomach.

Avoid milk, bran, grains, or cereals within 2 hours of taking Zinc Sulphate.
Use Zinc Sulphate regularly in order to get the most benefit from it.
To help you remember, use Zinc Sulphate at the same time(s) each day.



PRODUCTION, REACTIONS, STRUCTURE OF ZINC SULPHATE:
Zinc sulfate is produced by treating virtually any zinc-containing material (metal, minerals, oxides) with sulfuric acid.
Specific reactions include the reaction of the metal with aqueous sulfuric acid:
Zn + H2SO4 + 7 H2O → ZnSO4·7H2O + H2

Pharmaceutical-grade zinc sulfate is produced by treating high-purity zinc oxide with sulfuric acid:
ZnO + H2SO4 + 6 H2O → ZnSO4·7H2O
In aqueous solution, all forms of zinc sulfate behave identically.

These aqueous solutions consist of the metal aquo complex [Zn(H2O)6]2+ and SO2−4 ions.
Barium sulfate forms when these solutions are treated with solutions of barium ions:
ZnSO4 + BaCl2 → BaSO4 + ZnCl2

With a reduction potential of −0.76 V, zinc(II) reduces only with difficulty.
When heated above 680 °C, Zinc Sulphate decomposes into sulfur dioxide gas and zinc oxide fume, both of which are hazardous.
The heptahydrate is isostructural with ferrous sulfate heptahydrate. The solid consists of [Zn(H2O)6]2+ ions interacting with sulfate and one water of crystallization by hydrogen bonds.

Anhydrous Zinc Sulphate is isomorphous with anhydrous copper(II) sulfate.
Zinc Sulphate exists as the mineral zincosite.
A monohydrate is known.
The hexahydrate is also recognized.



MINERALS OF ZINC SULPHATE:
As a mineral, ZnSO4•7H2O is known as goslarite.
Zinc Sulphate occurs as several other minor minerals, such as zincmelanterite, (Zn,Cu,Fe)SO4·7H2O (structurally different from goslarite).
Lower hydrates of Zinc Sulphate are rarely found in nature: (Zn,Fe)SO4·6H2O (bianchite), (Zn,Mg)SO4·4H2O (boyleite), and (Zn,Mn)SO4·H2O (gunningite).



WHAT ARE SOME PRODUCTS THAT CONTAIN ZINC SULPHATE?
Products containing Zinc Sulphate can be granular, pelleted, tableted, wettable powders, or dusts.



HOW DOES ZINC SULPHATE WORK?
Zinc binds to proteins or organic acids in plants.
In high concentrations, Zinc Sulphate affects the growth of moss and other plants, and damages the cells causing them to turn yellow.



WHAT HAPPENS TO ZINC SULPHATE WHEN IT ENTERS THE BODY?
Zinc is an essential element and it is required to support the normal function of the human body.
Our body adjusts its internal environment to keep zinc levels steady.
The zinc in Zinc Sulphate enters into the body if ingested, inhaled or by skin contact and enters the bloodstream.

Once inside, zinc moves throughout the body, binds to proteins, and enters different organs.
Zinc can be found in the bone, brain, heart, intestine, liver, kidney, lungs, muscle, pancreas, prostate, skin, and stomach.
Excess zinc is mainly eliminated in the feces; it can be excreted in the urine, sweat, and skin.



PHARMACODYNAMICS OF ZINC SULPHATE:
Zinc has been identified as a cofactor for over 70 different enzymes, including alkaline phosphatase, lactic dehydrogenase and both RNA and DNA polymerase.
Zinc facilitates wound healing, helps maintain normal growth rates, normal skin hydration and the senses of taste and smell.



MECHANISM OF ACTION OF ZINC SULPHATE:
Zinc inhibits cAMP-induced, chloride-dependent fluid secretion by inhibiting basolateral potassium (K) channels, in in-vitro studies with rat ileum.
This study has also shown the specificity of Zn to cAMP-activated K channels, because zinc did not block the calcium (Ca)-mediated K channels.

As this study was not performed in Zn-deficient animals, it provides evidence that Zn is probably effective in the absence of Zn deficiency.
Zinc also improves the absorption of water and electrolytes, improves regeneration of the intestinal epithelium, increases the levels of brush border enzymes, and enhances the immune response, allowing for a better clearance of the pathogens.



ABSORPTION OF ZINC SULPHATE:
Approximately 20 to 30% of dietary zinc is absorbed, primarily from the duodenum and ileum.
The amount absorbed is dependent on the bioavailability from food.
Zinc is the most bioavailable from red meat and oysters.

Phytates may impair absorption by chelation and formation of insoluble complexes at an alkaline pH.
After absorption, zinc is bound in the intestine to the protein metallothionein.
Endogenous zinc can be reabsorbed in the ileum and colon, creating an enteropancreatic circulation of zinc.



VOLUME OF DISTRIBUTION OF ZINC SULPHATE:
After absorption zinc is bound to protein metallothionein in the intestines.
Zinc is widely distributed throughout the body.
It is primarily stored in RBCs, WBCs, muscles, bones, Skin, Kidneys, Liver, Pancreas, retina, and prostate.



PHYSICAL and CHEMICAL PROPERTIES of ZINC SULPHATE:
Chemical formula: ZnSO4
Molar mass: 161.44 g/mol (anhydrous)
179.47 g/mol (monohydrate)
287.53 g/mol (heptahydrate)
Appearance: white powder
Odor: odorless
Density: 3.54 g/cm3 (anhydrous)
2.072 g/cm3 (hexahydrate)
Melting point: 680 °C (1,256 °F; 953 K) decomposes (anhydrous)
100 °C (heptahydrate)
70 °C, decomposes (hexahydrate)
Boiling point: 740 °C (1,360 °F; 1,010 K) (anhydrous)
280 °C, decomposes (heptahydrate)
Solubility in water: 57.7 g/100 mL, anhydrous (20 °C)
(In aqueous solutions with a pH < 5)

Solubility: alcohols
Magnetic susceptibility (χ): −45.0·10−6 cm3/mol
Refractive index (nD): 1.658 (anhydrous), 1.4357 (heptahydrate)
Thermochemistry:
Std molar entropy (S⦵298): 120 J·mol−1·K−1
Std enthalpy of formation (ΔfH⦵298): −983 kJ·mol−1
Molecular Weight: 161.4 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 159.880871 g/mol
Monoisotopic Mass: 159.880871 g/mol
Topological Polar Surface Area: 88.6Ų
Heavy Atom Count: 6

Formal Charge: 0
Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
ZnSO4: Zinc Sulfate
Molecular Weight/ Molar Mass: 161.47 g/mol
Density: 3.54 g/cm³
Boiling Point: 740 °C
Melting Point: 680 °C
Physical state: liquid

Color: colorless
Odor: odorless
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: Not applicable
Decomposition temperature: No data available
pH: ca.4,8 at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: at 20 °C soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: ca.1,02 g/m3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available



FIRST AID MEASURES of ZINC SULPHATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC SULPHATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC SULPHATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC SULPHATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: > 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: > 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: filter ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC SULPHATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage class:
Storage class (TRGS 510): 12:
Non Combustible Liquids



STABILITY and REACTIVITY of ZINC SULPHATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available


ZINC SULPHATE HEPTAHYDRATE

Zinc sulfate heptahydrate, also known as zinc sulphate heptahydrate, is a chemical compound with the formula ZnSO₄·7H₂O.
Zinc sulfate heptahydrate is a hydrated form of zinc sulfate, which means it contains water molecules within its crystal structure.
Zinc sulfate heptahydrate is composed of zinc ions (Zn²⁺) bonded to sulfate ions (SO₄²⁻), along with seven water molecules (H₂O) per formula unit.

CAS number: 7446-20-0
EC number: 231-793-3



APPLICATIONS


Zinc sulfate heptahydrate has several applications across various industries.
Here are some of its main uses:

Agriculture:
Zinc sulfate heptahydrate is commonly used as a fertilizer additive to correct zinc deficiency in soil.
Zinc sulfate heptahydrate provides an essential nutrient for plant growth and development.

Animal Feed:
Zinc sulfate heptahydrate is added to animal and poultry feed as a nutritional supplement.
Zinc sulfate heptahydrate ensures adequate zinc intake, which is crucial for proper growth, metabolism, and immune function in animals.

Industrial Applications:
Zinc sulfate heptahydrate finds applications in various industrial processes, including:

a. Production of Dyes and Pigments:
Zinc sulfate heptahydrate is used as a precursor in the manufacturing of zinc-based dyes and pigments.

b. Wood Preservation:
Zinc sulfate heptahydrate is used as a wood preservative to protect against fungal and insect attacks.

c. Mining:
Zinc sulfate heptahydrate serves as a flotation agent in the mining industry to separate zinc minerals from other ores.

d. Electroplating:
Zinc sulfate heptahydrate is utilized in the electroplating industry to provide a protective zinc coating on metals.

Medical and Pharmaceutical Uses:
Zinc sulfate heptahydrate has applications in the medical field, such as:

a. Topical Treatments:
Zinc sulfate heptahydrate is found in some topical ointments and creams used to treat skin conditions like acne, eczema, and dermatitis.

b. Nutritional Supplements:
In certain cases of zinc deficiency, Zinc sulfate heptahydrate may be administered orally as a dietary supplement.

Analytical Chemistry:
Zinc sulfate heptahydrate is used as a reagent in analytical chemistry for detecting and quantifying other substances.
Zinc sulfate heptahydrate finds applications in laboratory settings for various chemical experiments.

Water Treatment:
Zinc sulfate heptahydrate has been studied for its potential application in wastewater treatment to remove heavy metals and clarify water.

These are some of the prominent applications of zinc sulfate heptahydrate.
Its versatile properties make it useful in diverse fields ranging from agriculture and industry to healthcare and environmental applications.
In addition to the applications mentioned earlier, zinc sulfate heptahydrate has several other uses.
Here are some additional applications:

Galvanizing:
Zinc sulfate heptahydrate is used in the galvanizing process, which involves coating iron or steel with a protective layer of zinc.
This helps prevent corrosion and extends the lifespan of metal structures.

Water Treatment Additive:
Zinc sulfate heptahydrate can be employed as an additive in water treatment processes to control algae growth and aid in the removal of turbidity and impurities.

Agricultural Pesticide:
Zinc sulfate heptahydrate is sometimes used as an ingredient in agricultural pesticides and herbicides to help control pests and unwanted plant growth.

Veterinary Medicine:
Apart from its use in animal feed, Zinc sulfate heptahydrate may be used in veterinary medicine for the treatment of specific conditions or as a nutritional supplement for animals.

Chemical Synthesis:
Zinc sulfate heptahydrate serves as a precursor or catalyst in various chemical reactions and synthesis processes.
Zinc sulfate heptahydrate is used in the production of other zinc compounds and chemical derivatives.

Laboratory Reagent:
Zinc sulfate heptahydrate finds application as a reagent in laboratory experiments, particularly in chemistry and biology, where it may be used for precipitation reactions or as a source of zinc ions.

Electrolyte for Batteries:
Zinc sulfate heptahydrate can be utilized as an electrolyte in certain types of batteries, including zinc-carbon batteries, due to its ability to conduct electricity.

Soil Stabilization:
In some cases, zinc sulfate heptahydrate is used to stabilize soil or control dust on roads and construction sites.

Textile Industry:
Zinc sulfate heptahydrate is employed in the textile industry as a mordant, which helps fix dyes to fabrics and improves colorfastness.

Printing and Paper Industry:
Zinc sulfate heptahydrate may be used in the printing and paper industry for the production of specialized papers and coatings.

Galvanizing:
Zinc sulfate heptahydrate is used in the galvanizing process, which involves coating iron or steel with a protective layer of zinc.
This helps prevent corrosion and extends the lifespan of metal structures.

Water Treatment Additive:
Zinc sulfate heptahydrate can be employed as an additive in water treatment processes to control algae growth and aid in the removal of turbidity and impurities.

Agricultural Pesticide:
Zinc sulfate heptahydrate is sometimes used as an ingredient in agricultural pesticides and herbicides to help control pests and unwanted plant growth.

Veterinary Medicine:
Apart from its use in animal feed, zinc sulfate heptahydrate may be used in veterinary medicine for the treatment of specific conditions or as a nutritional supplement for animals.

Chemical Synthesis:
Zinc sulfate heptahydrate serves as a precursor or catalyst in various chemical reactions and synthesis processes.
Zinc sulfate heptahydrate is used in the production of other zinc compounds and chemical derivatives.

Laboratory Reagent:
Zinc sulfate heptahydrate finds application as a reagent in laboratory experiments, particularly in chemistry and biology, where it may be used for precipitation reactions or as a source of zinc ions.

Electrolyte for Batteries:
Zinc sulfate heptahydrate can be utilized as an electrolyte in certain types of batteries, including zinc-carbon batteries, due to its ability to conduct electricity.

Soil Stabilization:
In some cases, zinc sulfate heptahydrate is used to stabilize soil or control dust on roads and construction sites.

Textile Industry:
Zinc sulfate heptahydrate is employed in the textile industry as a mordant, which helps fix dyes to fabrics and improves colorfastness.

Printing and Paper Industry:
Zinc sulfate heptahydrate may be used in the printing and paper industry for the production of specialized papers and coatings.


Zinc sulfate heptahydrate is widely used in agriculture as a fertilizer additive to correct zinc deficiency in soil.
Zinc sulfate heptahydrate plays a crucial role in plant growth and development, promoting healthy root systems and improving crop yields.

Zinc sulfate heptahydrate is added to animal feed as a nutritional supplement to ensure proper growth, metabolism, and immune function in animals.
Zinc sulfate heptahydrate is used in the production of zinc-based dyes and pigments for various industries, including textiles, paints, and coatings.

Zinc sulfate heptahydrate acts as a wood preservative, protecting against fungal decay and insect damage.
In the mining industry, Zinc sulfate heptahydrate serves as a flotation agent to separate valuable zinc minerals from other ores during the extraction process.
Zinc sulfate heptahydrate finds applications in electroplating, providing a protective zinc coating on metals to prevent corrosion.

Zinc sulfate heptahydrate is utilized in the galvanizing process to coat iron or steel structures, offering corrosion resistance.
Zinc sulfate heptahydrate is used as an additive in water treatment processes to control algae growth and improve water clarity.

Zinc sulfate heptahydrate may be included in agricultural pesticides and herbicides to help control pests and unwanted plant growth.
In veterinary medicine, it is used as a supplement or treatment for specific conditions in animals.

Zinc sulfate heptahydrate is employed as a reagent in chemical synthesis and laboratory experiments, facilitating various reactions.
Zinc sulfate heptahydrate can serve as a mordant in the textile industry, aiding in the fixation of dyes to fabrics and enhancing colorfastness.
Zinc sulfate heptahydrate is used in the printing and paper industry to produce specialized papers and coatings.

In certain types of batteries, including zinc-carbon batteries, it is used as an electrolyte for electrical conductivity.
Zinc sulfate heptahydrate is utilized in wastewater treatment to remove heavy metals and clarify water.

Zinc sulfate heptahydrate is employed as a soil stabilizer or dust suppressant in construction sites and roadways.
Zinc sulfate heptahydrate is used in some topical ointments and creams for the treatment of skin conditions like acne and eczema.
In analytical chemistry, it can be used as a reagent for detecting and quantifying other substances.

Zinc sulfate heptahydrate finds applications in the production of other zinc compounds and chemical derivatives.
Zinc sulfate heptahydrate is used in certain industrial processes as a corrosion inhibitor to protect metals from degradation.

Zinc sulfate heptahydrate is involved in the production of specialized papers, such as blueprint paper and photographic paper.
In the manufacture of rubber products, it can be used as an activator in the vulcanization process.

Zinc sulfate heptahydrate is utilized in the production of adhesives, helping to enhance the adhesive properties of formulations.
Zinc sulfate heptahydrate has applications in the pharmaceutical industry, where it may be used as an excipient in tablet formulations.

In the automotive industry, zinc sulfate heptahydrate is used in the formulation of antifreeze and coolant solutions.
Zinc sulfate heptahydrate finds application as a component in the production of corrosion-resistant coatings for steel structures and automotive parts.

Zinc sulfate heptahydrate is utilized in the manufacturing of zinc-based dietary supplements for human consumption.
Zinc sulfate heptahydrate is added to some oral rehydration solutions to help replenish zinc levels in individuals with diarrhea.

Zinc sulfate heptahydrate is employed in the production of zinc oxide, which is used in sunscreens and cosmetic products.
Zinc sulfate heptahydrate can be used as a pH adjuster or buffer in various formulations, such as cosmetics and personal care products.

Zinc sulfate heptahydrate is used in the textile industry for mercerization, a process that enhances the luster and strength of cotton fibers.
Zinc sulfate heptahydrate finds application as a component in metal-working fluids to improve lubrication and prevent corrosion during machining processes.

Zinc sulfate heptahydrate is used in the production of zinc-based fungicides and herbicides for agricultural purposes.
Zinc sulfate heptahydrate is employed in the production of nutritional supplements for aquaculture and fish farming.
Zinc sulfate heptahydrate can be used as a nutrient additive in hydroponic systems, providing essential zinc for plant growth in soilless cultivation.

Zinc sulfate heptahydrate is utilized in the synthesis of zinc-containing catalysts for various chemical reactions.
Zinc sulfate heptahydrate is used as a reagent in laboratory tests for the detection and determination of zinc in biological and environmental samples.

Zinc sulfate heptahydrate can be utilized in the formulation of eye drops or ophthalmic solutions for certain eye conditions.
Zinc sulfate heptahydrate finds applications in the manufacture of ceramic glazes, providing desired colors and surface finishes.
Zinc sulfate heptahydrate is used in the production of zinc-based dietary supplements for livestock and poultry.

Zinc sulfate heptahydrate is employed in the treatment of moss and algae growth on roofs, walls, and pavement surfaces.
Zinc sulfate heptahydrate can be used as a component in corrosion inhibitors for cooling water systems and industrial equipment.

Zinc sulfate heptahydrate is utilized in the electroforming process to create intricate metal shapes or patterns on surfaces.
Zinc sulfate heptahydrate is added to some dental products, such as mouthwashes or toothpaste, for its potential antimicrobial properties.

Zinc sulfate heptahydrate finds application in the production of zinc-containing paints and coatings for corrosion protection in marine environments.
Zinc sulfate heptahydrate can be used in the production of zinc-based dietary supplements for poultry and livestock.

Zinc sulfate heptahydrate is employed in the preservation of fruits and vegetables to extend their shelf life.
Zinc sulfate heptahydrate is used as a nutritional supplement in aquaculture feeds to promote healthy growth and development in fish and crustaceans.
Zinc sulfate heptahydrate finds applications in the production of zinc-containing adhesives and sealants for various industries.



DESCRIPTION


Zinc sulfate heptahydrate, also known as zinc sulphate heptahydrate, is a chemical compound with the formula ZnSO₄·7H₂O.
Zinc sulfate heptahydrate is a hydrated form of zinc sulfate, which means it contains water molecules within its crystal structure.
Zinc sulfate heptahydrate is composed of zinc ions (Zn²⁺) bonded to sulfate ions (SO₄²⁻), along with seven water molecules (H₂O) per formula unit.

Zinc sulfate heptahydrate is a white crystalline solid that is highly soluble in water.
Zinc sulfate heptahydrate is commonly used in various applications.

It's worth noting that while zinc sulfate heptahydrate has several practical applications, it should be handled with care and stored properly, as it can be irritating to the eyes, skin, and respiratory system if not used appropriately.

Zinc sulfate heptahydrate is a crystalline compound with a white color.
Zinc sulfate heptahydrate has a molecular formula of ZnSO₄·7H₂O.

Zinc sulfate heptahydrate forms beautiful, needle-like crystals.
Zinc sulfate heptahydrate has a molecular weight of approximately 287.54 g/mol.

Zinc sulfate heptahydrate is highly soluble in water.
When dissolved in water, it forms a clear, colorless solution.

Zinc sulfate heptahydrate has a slightly acidic taste.
Zinc sulfate heptahydrate has a melting point of around 100 °C (212 °F).
At high temperatures, it can decompose and release toxic sulfur dioxide gas.

Zinc sulfate heptahydrate is commonly used as a nutritional supplement in animal feed.
Zinc sulfate heptahydrate is an important source of zinc, a vital nutrient for proper growth and development.
Zinc sulfate heptahydrate is often used in the manufacturing of fertilizers to enrich the soil with zinc.

Zinc sulfate heptahydrate is employed in the mining industry as a flotation agent to separate zinc minerals.
Zinc sulfate heptahydrate is used in the production of various pigments and dyes.

Zinc sulfate heptahydrate is utilized as a corrosion inhibitor in some industrial applications.
Zinc sulfate heptahydrate can be found in some topical ointments for treating skin conditions.

Zinc sulfate heptahydrate is known for its astringent and antimicrobial properties.
Zinc sulfate heptahydrate is commonly utilized in laboratory settings for chemical experiments.

Zinc sulfate heptahydrate can be used as a reagent in analytical chemistry for detecting and quantifying other substances.
Zinc sulfate heptahydrate has been studied for its potential application in wastewater treatment.
Zinc sulfate heptahydrate is a relatively stable compound when stored in appropriate conditions.

Zinc sulfate heptahydrate should be handled with care, as it may irritate the skin, eyes, and respiratory system.
Zinc sulfate heptahydrate is important to follow proper safety guidelines when working with this compound.

The compound's solubility in water allows for easy incorporation into various formulations.
Zinc sulfate heptahydrate has a wide range of applications in agriculture, industry, and healthcare.



PROPERTIES


Chemical formula: ZnSO₄·7H₂O
Molecular weight: Approximately 287.54 g/mol
Appearance: White, crystalline solid
Odor: Odorless
Solubility: Highly soluble in water
pH: Slightly acidic
Melting point: Approximately 100 °C (212 °F)
Boiling point: Decomposes before boiling
Density: 1.957 g/cm³
Crystal structure: Orthorhombic
Hydration: Heptahydrate form with seven water molecules per formula unit
Stability: Relatively stable under normal conditions
Toxicity: May be harmful if swallowed, inhaled, or in contact with eyes or skin
Irritancy: Can cause irritation to eyes, skin, and respiratory system
Reactivity: Can react with strong acids or bases
Decomposition: At high temperatures, it decomposes to release toxic sulfur dioxide gas
Solubility in other solvents: Insoluble in organic solvents such as ethanol and ether
Conductivity: Exhibits conductivity when dissolved in water
Crystal shape: Needle-like crystals or powder form
Optical properties: Transparent in thin crystal form
Magnetic properties: Non-magnetic
Absorption spectra: Absorbs light in the ultraviolet range
Hygroscopicity: Absorbs moisture from the air
Molecular geometry: Exhibits octahedral geometry around the central zinc ion
Corrosiveness: Can corrode or react with certain metals in the presence of moisture.



FIRST AID


Inhalation:

If inhaled, remove the affected person from the contaminated area to fresh air.
If the person is experiencing difficulty breathing, provide oxygen if available and seek medical attention immediately.
If breathing has stopped, administer artificial respiration and seek medical help promptly.


Skin Contact:

Remove contaminated clothing and immediately wash the affected skin with plenty of soap and water for at least 15 minutes.
If irritation or redness persists, seek medical advice.
Do not use solvents or chemicals to remove the substance from the skin.


Eye Contact:

Rinse the eyes thoroughly with gently flowing water for at least 15 minutes, keeping the eyelids open to ensure thorough rinsing.
Remove contact lenses, if applicable, after the initial rinsing.
Seek immediate medical attention and continue rinsing the eyes while waiting for medical assistance.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water if the person is conscious and able to swallow.
Seek immediate medical attention and provide the medical staff with the necessary details, such as the amount ingested and the time of ingestion.


General Safety Precautions:

Avoid direct contact with the substance and always wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat or protective clothing when handling zinc sulfate heptahydrate.
Handle the compound in a well-ventilated area or under fume hood to minimize the risk of inhalation.
Wash hands thoroughly with soap and water after handling the compound.
Follow proper disposal procedures for the substance and any contaminated materials.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):

Always wear appropriate PPE when handling zinc sulfate heptahydrate.
This includes gloves, safety goggles, and a lab coat or protective clothing to prevent direct contact with the substance.

Ventilation:

Handle the compound in a well-ventilated area or under a fume hood to minimize the risk of inhalation.
Adequate ventilation helps to maintain a safe working environment.

Avoiding Contamination:

Prevent contamination of the substance by avoiding contact with incompatible materials such as strong acids, bases, and organic solvents.
Use dedicated equipment and containers for handling and storing zinc sulfate heptahydrate to avoid cross-contamination.

Hygiene Practices:

Wash hands thoroughly with soap and water after handling the compound, especially before eating, drinking, or smoking.
Avoid touching your face, eyes, or mouth while working with the substance.
Do not eat, drink, or smoke in areas where the compound is handled.

Spills and Leaks:

In the event of a spill or leak, contain the area to prevent further spread and minimize contact with the substance.
Use appropriate absorbent materials, such as sand or vermiculite, to clean up small spills.
For larger spills or releases, follow established protocols and notify the appropriate authorities for proper cleanup and disposal.


Storage:

Container:

Store zinc sulfate heptahydrate in tightly closed, properly labeled containers made of compatible materials such as high-density polyethylene (HDPE) or glass.
Ensure that containers are free from leaks or damage to prevent contamination and moisture absorption.

Location:

Store the compound in a cool, dry, well-ventilated area away from incompatible substances.
Keep it away from sources of heat, ignition, and direct sunlight to prevent decomposition and potential fire hazards.
Temperature and Humidity:

Maintain stable storage conditions with temperature and humidity levels within recommended ranges.
Store the compound at room temperature (around 20-25°C or 68-77°F) and avoid extreme temperature fluctuations.

Separation:

Store zinc sulfate heptahydrate away from strong acids, bases, oxidizing agents, and organic materials to prevent reactions and potential hazards.
Segregate it from other chemicals based on compatibility to avoid cross-contamination.

Security and Accessibility:

Store the compound in a secure area with restricted access to authorized personnel only.
Ensure that the storage area is clearly labeled and the containers are properly identified.



SYNONYMS


Zinc sulphate heptahydrate
Zinc vitriol heptahydrate
White vitriol heptahydrate
Zinc(II) sulfate heptahydrate
Zinc(II) sulphate heptahydrate
Zinc salt heptahydrate
ZnSO₄·7H₂O
Zinc(II) sulphate heptahydrate
Zinc sulfate 7-hydrate
Zinc vitriol 7-hydrate
ZnSO₄·7H₂O
Zinc(II) sulphate 7-hydrate
Heptahydrated zinc sulfate
Zinc sulphate hydrate (7:1)
White vitriol 7-hydrate
Zinc sulfate monohydrate
Zinc(II) sulphate monohydrate
ZnSO₄·H₂O
Zinc sulphate monohydrate
Zinc sulfate monohydrated salt
Zinc vitriol monohydrate
Zinc(II) sulphate monohydrated salt
Heptahydrous zinc sulfate
Zinc sulphate monohydrate (7:1)
ZnSO₄·H₂O·6H₂O
Zinc sulfate hexahydrate
Zinc(II) sulphate hexahydrate
Zinc sulphate hexahydrated salt
Zinc vitriol hexahydrate
Hexahydrated zinc sulfate
Zinc sulfate hexahydrated salt
Zinc(II) sulphate hexahydrated salt
Zinc sulphate 7H2O
Zinc sulfate hepta-hydrate
Heptahydrated zinc sulphate
ZnSO4·7(H2O)
Zinc(II) sulphate hepta-hydrate
Zinc vitriol 7H2O
Zinc sulfate hepta-hydrated salt
Zinc sulphate 7-water
ZnSO4·7H2O·H2O
Zinc sulfate hepta-hydrated compound
Zinc(II) sulphate hepta-hydrated compound
Heptahydrous zinc sulphate
Zinc sulfate hepta-hydrated form
Zinc sulphate hepta-hydrate salt
ZnSO4·7H2O·6H2O
Zinc sulfate 6-hydrate
Zinc(II) sulphate 6-hydrate
Zinc vitriol 6-hydrate
Hexahydrated zinc sulphate
Zinc sulfate hexa-hydrated salt
Zinc sulphate hexa-hydrated form
ZnSO4·H2O·6H2O
Zinc sulfate hexa-hydrated compound
Zinc(II) sulphate hexa-hydrated compound
Zinc vitriol hexa-hydrate

ZINC SULPHATE HEPTAHYDRATE
Zinc Sulphate Heptahydrate is a hydrate that is the heptahydrate form of zinc sulfate.
Zinc Sulphate Heptahydrate is a hydrate and a metal sulfate.
Zinc Sulphate Heptahydrate contains a zinc sulfate.


CAS NUMBER: 7446-20-0

EC NUMBER: -

MOLECULAR FORMULA: ZnSO4. 7H2O

MOLECULAR WEIGHT: 287.6 g/mol

IUPAC NAME: zinc;sulfate;heptahydrate



Zinc Sulphate Heptahydrate (ZnSO4•7H2O) occurs in nature as the mineral goslarite.
Chemists manufacture it by treating any metal that contains zinc with sulfuric acid.
For pharmaceutical use, chemists use high-purity zinc oxide to obtain the ZnSO4•7H2O.

Zinc Sulphate Heptahydrate has applications in many industries, including printing, electroplating, agriculture and health.
Bisley supplies ZnSO4•7H2O to the agricultural sector.

Zinc Sulphate Heptahydrate was historically known as white vitriol.
Zinc Sulphate Heptahydrate's a colourless solid, usually a white powder or crystals.
Zinc Sulphate Heptahydrate should be stored at room temperature.

Zinc Sulfate Heptahydrate is a moderately water and acid soluble Zinc source for uses compatible with sulfates.
Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal.
Zinc Sulfate Heptahydrate is generally immediately available in most volumes

APPLICATIONS:
As we mentioned, multiple industries utilise zinc sulphate for various applications.

Agriculture:
Fertilisers and agricultural sprays utilise this compound to supplement zinc in plants.
The compound also prevents moss growth on roots.
Additionally, zinc sulphate acts as a supplement in animal feeds.

Pharmaceutical:
Doctors prescribe zinc sulphate hydrates as part of oral rehydration therapy.
They use it to treat diarrhoea or stomach issues related to zinc deficiency.
Some people use it as a dietary supplement, and doctors also use it in intravenous feeding.
Toothpaste also utilises zinc sulphate hydrates.

Industrial:
Rayon production utilises zinc sulphate heptahydrate.
The printing industry uses it to produce lithopone.
Zinc Sulphate Heptahydrate also acts as an electrolyte in the electroplating industry.
Preservation of skins and leather also utilises zinc sulphate.
Distillers and brewers use zinc sulphate to increase the alcohol yield of the yeast in the brewing process.

Zinc Sulphate Heptahydrate is an inorganic compound.
Zinc Sulphate Heptahydrate is used as a dietary supplement to treat zinc deficiency and to prevent the condition in those at high risk.

Zinc Sulphate Heptahydrate was historically known as "white vitriol".
Zinc Sulphate Heptahydrate is colourless solids.

In medicine Zinc Sulphate Heptahydrate is used together with oral rehydration therapy (ORT) and an astringent.
Zinc Sulphate Heptahydrate is used to supply zinc in animal feeds, fertilizers, toothpaste, and agricultural sprays.

Zinc Sulphate Heptahydrate, like many zinc compounds, can be used to control moss growth on roofs.
Zinc Sulphate Heptahydrate can be used to supplement zinc in the brewing process.

Zinc Sulphate Heptahydrate is a necessary nutrient for optimal yeast health and performance, although it is not a necessary supplement for low-gravity beers, as the grains commonly used in brewing already provide adequate zinc.
Zinc Sulphate Heptahydrate is a more common practice when pushing yeast to their limit by increasing alcohol content beyond their comfort zone.

Zinc Sulphate Heptahydrate is a fertiliser containing zinc and sulphur used for combating a zinc deficiency in plants such as fruits and vegetables, flowers, vines and ornamentals grown in both soil and soilless variations.

Zinc Sulphate Heptahydrate granular powder is a simple source of zinc for where the nutrient is lacking.
Zinc Sulphate Heptahydrate is an essential growth factor for many strains of yeast.

A healthy yeast requires many nutrients to sustain its growth.
Zinc Sulphate Heptahydrate acts as a metal ion co-factor, catalysing several enzymic reactions that would otherwise not take place or at a very slow rate.

Zinc Sulphate Heptahydrate granular powder is a simple source of zinc for where the nutrient is lacking.
Zinc Sulphate Heptahydrate can be added to animal feeds in order to counteract zinc deficiencies.

Zinc Sulphate Heptahydrate is an essential growth factor for many strains of yeast.
Zinc Sulphate Heptahydrate is used in the following products: metal surface treatment products, non-metal-surface treatment products, pH regulators and water treatment products and laboratory chemicals.

Zinc Sulphate Heptahydrate has an industrial use resulting in manufacture of another substance (use of intermediates).
Zinc Sulphate Heptahydrate is used in the following areas: formulation of mixtures and/or re-packaging.

Zinc Sulphate Heptahydrate is used for the manufacture of: chemicals, fabricated metal products, machinery and vehicles and wood and wood products.4
Zinc Sulphate Heptahydrate is widely used as a coagulant in the production of rayon.

Zinc Sulphate Heptahydrate finds an application in the manufacturing of calico printing, wood preservation and lithopone.
Zinc Sulphate Heptahydrate is the source of zinc which is supplied in animal feeds, fertilizers and agricultural sprays.

Zinc Sulphate Heptahydrate is utilized as electrolytes for zinc plating and surface treating agents.
Zinc Sulphate Heptahydrate is also used as a mordant in dyeing, preservative for skin and leather and in medicine as an astringent and emetic.


PHYSICAL PROPERTIES:

-Molecular Weight: 287.6 g/mol

-Exact Mass: 285.954824 g/mol

-Monoisotopic Mass: 285.954824 g/mol

-Topological Polar Surface Area: 95.6Ų

-Physıcal Description: Granules or Crystaline Powder

-Melting Point: 100 °C

-Solubility: 54 g/ml

-Density: 1.97 g/cm³

-Form: Solid

-Specific Gravity: 1.97

-Color: White

-pH 4-6

-Odor: Odorless


Zinc Sulphate Heptahydrate is odourless, hygroscopic and easily soluble in water.
Zinc Sulphate Heptahydrate is a white, powdery or pearly product.

Zinc Sulphate Heptahydrate is a white fine crystalline powder.
Zinc Sulphate Heptahydrate is an inorganic substance containing a zinc metal cation and a sulfate anion in its chemical structure.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 7

-Hydrogen Bond Acceptor Count: 11

-Rotatable Bond Count: 0

-Heavy Atom Count: 13

-Formal Charge: 0

-Complexity: 62.2

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 9

-Compound Is Canonicalized: Yes


Zinc Sulphate Heptahydrate is a salt of zinc metal.
Zinc Sulphate Heptahydrate is used in fertilizers and other agricultural sprays as a zinc supplement in plants.

Zinc Sulphate Heptahydrate also helps in inhibiting the moss growth on plant roots.
Zinc Sulphate Heptahydrate is used widely in the electroplating industry as an electrolyte.

Zinc Sulphate Heptahydrate is an inorganic substance containing a zinc metal cation and a sulfate anion in its chemical structure.
Zinc Sulphate Heptahydrate is a salt of zinc metal.

Moreover, the sulphate molecules having water of crystallization is the most common form of zinc sulphate.
There can be different hydrated forms of this substance, but heptahydrate form is the most common among them.
Furthermore, Zinc Sulphate Heptahydrate forms are all colorless crystal forms.

Zinc Sulphate Heptahydrate is a hydrated form of zinc sulphate where there are seven molecules for crystallization.
The chemical for this compound is ZnSO4.7H2O, while the molar mass of this compound is 287.54 g/mol.

This hydrated form of zinc sulphate is the most common form among other hydrates of zinc sulphate.
Historically, Zinc Sulphate Heptahydrate was named "white vitriol."

Zinc Sulphate Heptahydrate appears as colorless crystals.
However, Zinc Sulphate Heptahydrate is commercially available in white crystalline powder form.

When considering the applications of zinc sulphate heptahydrate, it is useful as a coagulant in the production of rayon.
Moreover, Zinc Sulphate Heptahydrate is important as a precursor for pigment lithopone.

In addition, Zinc Sulphate Heptahydrate is used in leather and medicine as an astringent and emetic
Zinc Sulphate Heptahydrate is used as a laboratory reagent

Zinc Sulphate Heptahydrate can be used as a dietary supplement for animal feed
Zinc Sulphate Heptahydrate is used as a component in fertilizers, and agricultural sprays, etc.

Zinc Sulphate Heptahydrate is an essential growth factor for many strains of yeast
The main application of Zinc Sulphate Heptahydrate is as a coagulant in the production of rayon.

Zinc Sulphate Heptahydrate is also a precursor to the pigment lithopone.
Zinc Sulphate Heptahydrate is used to supply zinc in animal feeds, fertilizers, and agricultural sprays.

Zinc Sulphate Heptahydrate is used as in electrolytes for zinc plating, as a mordant in dyeing, as a preservative for skins
In leather and in medicine as an astringent and emetic
Zinc Sulphate Heptahydrate is also used as laboratory reagent

At room temperature, Zinc Sulphate Heptahydrate is white particles or powder
Zinc Sulphate Heptahydrate is orthorhombic crystal

Zinc Sulphate Heptahydrate has convergence
Zinc Sulphate Heptahydrate is common astringent

Zinc Sulphate Heptahydrate weathers in dry air.
When be heated 30℃, Zinc Sulphate Heptahydrate can lose a part of crystal water

At 100℃ Zinc Sulphate Heptahydrate loses six crystal water molecules
Zinc Sulphate Heptahydrate loses seven crystal water molecules at 280℃

Zinc Sulphate Heptahydrate decomposes into zinc oxide and sulfur trioxide at 767℃.
Zinc Sulphate Heptahydrate is soluble in water, slightly soluble in ethanol and glycerol.

Zinc Sulphate Heptahydrate requires confined preservation.
Zinc Sulphate Heptahydrate is mainly used as raw material for the production of zinc, barium and other zinc saline

Zinc Sulphate Heptahydrate is also important auxiliary raw material for the viscose fiber and vinylon fiber
Zinc Sulphate Heptahydrate can be also used as mordant dyeing

Zinc Sulphate Heptahydrate is used as leather and wood preservative
Zinc Sulphate Heptahydrate can be used as a glue clarifying and preserving agents

Zinc Sulphate Heptahydrate also used as a medical emetic and fungicides
Zinc Sulphate Heptahydrate can be used for trace element fertilizers on agriculture.

Zinc Sulphate Heptahydrate can be used as mordant dyeing, wood preservatives, paper bleaching agent
Zinc Sulphate Heptahydrate can be also used in medicine, synthetic fibers, electrolysis, electroplating, pesticides and production of zinc, etc.
Zinc Sulphate Heptahydrate can be used for the preparation of zinc medicine, astringents, etc.

Zinc Sulphate Heptahydrate can be used as mordant, wood preservatives, bleach paper industry
Zinc Sulphate Heptahydrate is also used in medicine, synthetic fibers, electrolysis, electroplating, pesticides and production of zinc, etc.

Zinc Sulphate Heptahydrate is zinc supplement of dietary, the component of many enzymes, proteins, such as ribose animals involved in carbohydrate and fat metabolism, and it can catalyze interconversion of pyruvate and lactate, it can promote growth.
Zinc deficiency can lead to incomplete keratosis, stunted growth and deterioration of the hair, and it can affect animal reproductive function.

Zinc Sulphate Heptahydrate is allowed to use in food supplements of zinc.
Zinc Sulphate Heptahydrate is mainly used for man-made fibers coagulating liquid.

In printing and dyeing industry, Zinc Sulphate Heptahydrate is used as mordant, salt-stained blue Lamine alkali agent.
Zinc Sulphate Heptahydrate is main raw material of manufacturing inorganic pigments (e.g. lithopone), other zinc salts (e.g. zinc stearate, basic zinc carbonate) and zinc-containing catalyst.

Zinc Sulphate Heptahydrate is used as wood preservatives and leather, bone glue clarifying and preserving agents.
In pharmaceutical industry, it is used as emetic.

Zinc Sulphate Heptahydrate can also be used to prevent diseases and fruit tree nurseries and cable manufacturing zinc fertilizer and so on.
Zinc Sulphate Heptahydrate can be used as nutritional supplements (zinc enhancer) and the like in food-grade product.
Zinc Sulphate Heptahydrate can be used as analytical reagents, mordant and the phosphor matrix.


SYNONYMS:

ZINC SULFATE HEPTAHYDRATE
7446-20-0
Zincsulfateheptahydrate
Zinc sulfate (1:1) heptahydrate
zinc sulphate heptahydrate
Zinc sulfate (heptahydrate)
Zinc sulfate
zinc;sulfate;heptahydrate
Sulfato de zinc
Zinc vitriol (heptahydrate)
N57JI2K7WP
Zinc sulfate heptahydrate (1:1:7)
White vitriol (heptahydrate)
Sulfuric acid, zinc salt (1:1), heptahydrate
CCRIS 5563
Zinc sulfate (ZnSO4) heptahydrate
ZINCUM SULPHURICUM
MFCD00149894
UNII-N57JI2K7WP
ZnSO4.7H2O
zinc(2+) sulfate heptahydrate
Salt of Vitriol
DTXSID0040175
CHEBI:32312
ZINC SULPHATE (HEPTAHYDRATE)
zinc(2+) sulfate--water (1/7)
ZINC SULPHATE (1:1) HEPTAHYDRATE
zinc(II) sulfate heptahydrate
O4SZn.7H2O
Ophthazinc T
Ophthazinc T (TN)
Zinc sulfate hydrate (JP17)
O4-S-Zn.7H2-O
DTXCID8020175
Zinc sulfate hydrate (1:1:7)
ZINCUM SULPHURICUM
RZLVQBNCHSJZPX-UHFFFAOYSA-L
ZINC SULFATE HYDRATE
Zinc sulfate heptahydrate
AKOS015907730
LS-3231
ZINC SULFATE HEPTAHYDRATE
FT-0645104
D01081
ZINCI SULFAS HEPTAHYDRATE
A838141
Q27114864
ZINC SULFATE
ZINC SULPHATE HEPTAHYDRATE
ZINC SULPHATE HEPTA
7446-20-0
ZINC VITRIOL
ZINC SULFATE HEPTA
Goslarite
VasoClear A
Ophthazinc T
ZINCI SULFAS
Zinc sulfate heptahydrate
Sulfate de zinc, hydrate (1:1:7)
zinc sulfate heptahydrate (1:1:7)
Zinc sulfate hydrate (1:1:7)
zinc sulphate 7-hydrate
Zinc sulphate heptahydrate
zinc(2+) sulfate heptahydrate
16788-42-4
231-793-3
7446-20-0
7733-02-0
MFCD00149894
Ophthazinc T
Ophthazinc T (TN)
SULFURIC ACID, ZINC SALT, HEPTAHYDRATE
UNII:N57JI2K7WP
UNII-N57JI2K7WP
VasoClear A
Verazinc
White vitriol
White vitriol (heptahydrate)
Zinc sulfate
Zinc sulfate (JP15)
Zinc sulfate [JAN]
zinc sulfate 7-hydrate
Zinc sulfateZnSO4.7H2Ozinc sulfate (1:1) heptahydratezinc sulfate heptahydrate (1:1:7)
Zinc sulphate hydrate
Zinc vitriol (heptahydrate)
zinc(2+) sulfate heptahydratezinc(2+) sulfate--water (1/7)
zinc;sulfate;heptahydrate
Zincfrin
Zinci Sulfas
zincsulfateheptahydrate
ZINC SULPHATE HEPTAHYDRATE (ZNSO4∙7H2O)

Zinc sulfate heptahydrate, often represented as ZnSO₄·7H₂O, is a chemical compound composed of zinc, sulfur, and oxygen.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a hydrated form of zinc sulfate, meaning it contains water molecules in its crystalline structure.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a crystalline compound with a distinct rhombic crystal structure.

CAS Number: 7446-20-0
EC Number: 616-097-3

Zinc sulphate heptahydrate, Zinc sulfate 7-hydrate, Zinc sulfate 7-water, ZnSO₄·7H₂O, White vitriol, Sulfuric acid zinc salt heptahydrate, Sulfuric acid zinc salt 7-hydrate, Zinc vitriol, Zinc(II) sulfate heptahydrate, Zinc(II) sulphate 7-hydrate, ZnSO₄·7H₂O hydrate, Zinc sulfate monohydrate, Zinc sulfate hydrate, Zinc sulphate hydrate, Zinc sulfate crystal, Zinc sulfate 7-aqueous, Zinc sulfate heptahydrate crystal, ZnSO₄·7H₂O crystal, Zinc sulfate 7-aqueous crystal, Zinc(II) sulfate hydrate, Zinc vitriol 7-water, Zinc(II) sulphate heptahydrate, ZnSO₄·7H₂O salt, Zinc sulfate 7-hydrate salt, Zinc sulfate 7-water salt, Zinc sulfate heptahydrate salt, ZnSO₄·7H₂O compound, Zinc sulfate compound, Zinc sulphate compound, ZnSO₄·7H₂O powder, Zinc sulfate powder, Zinc sulphate powder, ZnSO₄·7H₂O substance, Zinc sulfate substance, Zinc sulphate substance, ZnSO₄·7H₂O material, Zinc sulfate material, Zinc sulphate material, Zinc sulfate 7-aqueous material, ZnSO₄·7H₂O solution, Zinc sulfate solution, Zinc sulphate solution, Zinc sulfate heptahydrate solution, ZnSO₄·7H₂O preparation, Zinc sulfate preparation, Zinc sulphate preparation, ZnSO₄·7H₂O formulation, Zinc sulfate formulation, Zinc sulphate formulation, Zinc sulfate 7-hydrate formulation, ZnSO₄·7H₂O mixture, Zinc sulfate mixture, Zinc sulphate mixture, ZnSO₄·7H₂O compound, Zinc sulfate compound, Zinc sulphate compound.



APPLICATIONS


Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a vital component in the formulation of micronutrient supplements for crops, ensuring optimal growth.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in horticulture to correct zinc deficiencies in plants, especially in fruit orchards and vegetable crops.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is incorporated into foliar sprays to deliver zinc directly to plant leaves for quick absorption.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is employed in the preparation of foot rot remedies for livestock to treat and prevent hoof-related issues.
In the creation of zinc-based pigments, it contributes to the vibrant colors seen in paints and coatings.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) acts as a flocculating agent in wastewater treatment, aiding in the removal of impurities.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) finds utility in the synthesis of fungicides, contributing to disease control in crops.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in the production of galvanic cells, playing a role in batteries and energy storage.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) serves as a corrosion inhibitor, protecting metals from rust and corrosion in industrial applications.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is applied in the production of fireproofing agents, enhancing fire resistance in certain materials.
In veterinary medicine, it is included in formulations to address zinc deficiencies in pets and livestock.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is extensively used as a zinc fertilizer in agriculture to address zinc deficiencies in soil.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) plays a crucial role in promoting healthy plant growth, aiding in processes such as photosynthesis and enzyme activation.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) serves as a dietary supplement for animals, providing essential zinc for proper growth and development.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) contributes to animal health by preventing and addressing zinc deficiencies in livestock.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is employed in wood preservation treatments to protect wood from decay and insects.
In metal industries, zinc sulfate solutions may be used in the galvanizing process to coat metals with a protective zinc layer.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is utilized in electroplating processes for depositing zinc coatings on various surfaces.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a component in the synthesis of certain chemicals, including the preparation of other zinc compounds.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) finds application in the textile industry as a mordant in dyeing processes.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) has several uses in different industries:
Agriculture
Plant Growth:
Animal Nutrition
Water Treatment
Chemical Industry
Topical Preparations
Pigments and Dyes
Fertilizer Blends
Skin Care Products
Animal Health
Seed Treatment

In the pharmaceutical industry, it is utilized in certain topical formulations for treating skin conditions.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is employed in water treatment processes to control the growth of algae.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) serves as a reagent in various chemical reactions and analyses in laboratories.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in the manufacturing of pigments and dyes for coloring materials.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is crucial for various biological processes, acting as a cofactor for enzymes.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is included in fertilizer blends to provide a balanced nutrient profile for plants.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is sometimes used as a seed treatment to enhance seed germination and early seedling development.
In the cosmetic industry, it can be found in certain skin care products for its beneficial properties.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in the electroplating of zinc onto steel surfaces for corrosion protection.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) plays a role in the galvanization of steel structures, enhancing their durability and lifespan.
In the production of rayon, zinc sulfate is used as a coagulant in the spinning process.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) aids in the treatment of acne and skin conditions when included in certain skincare products.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is involved in the formulation of nutritional supplements for both human and animal consumption.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is utilized in the production of feed additives to enhance zinc content in animal diets.
In the production of pigmented inks, zinc sulfate contributes to the coloration of printing materials.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in educational laboratories to demonstrate precipitation reactions and crystal formation.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) acts as a catalyst in some chemical reactions, influencing the rate of reaction without being consumed.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is an essential component in the formulation of metalworking fluids, aiding in machining processes.
In the field of metallurgy, it is utilized for the purification of zinc during the extraction process.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) may be used in the petroleum industry for removing impurities from crude oil.
In the leather industry, Zinc sulphate heptahydrate (ZNSO4∙7H2O) can be employed in tanning processes to preserve and treat hides.
Some wound care products may contain zinc sulfate for its potential wound-healing properties.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) has historical significance in photography as a component in developing solutions.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in the manufacturing of certain adhesives.
In the construction industry, it may be added to concrete as a setting accelerator.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is used in various laboratory experiments and research studies across different scientific disciplines.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is employed in educational settings for experiments and demonstrations illustrating chemical principles.
The leather industry utilizes zinc sulfate as a mordant in the dyeing process to fix colors to leather.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is employed in the manufacturing of wood preservatives, protecting against decay and insect damage.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is added to poultry feed to maintain optimal zinc levels for bird health.



DESCRIPTION


Zinc sulfate heptahydrate, often represented as ZnSO₄·7H₂O, is a chemical compound composed of zinc, sulfur, and oxygen.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a hydrated form of zinc sulfate, meaning it contains water molecules in its crystalline structure.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a crystalline compound with a distinct rhombic crystal structure.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) appears as colorless or white granules, forming characteristic rhombic crystals.
ZnSO₄·7H₂O is commonly known as white vitriol due to its appearance and historical uses.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is highly soluble in water, forming a clear solution with a slightly acidic pH.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) has a molecular weight of approximately 287.56 g/mol.
In its hydrated form, each unit of zinc sulfate is associated with seven water molecules.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is commonly used in agriculture as a zinc fertilizer to address soil zinc deficiencies.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is an essential source of zinc for plants, promoting healthy growth and development.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) plays a crucial role in various biological processes and is utilized in animal nutrition.
As a dietary supplement, Zinc sulphate heptahydrate (ZNSO4∙7H2O) provides a bioavailable form of zinc for animals.
The crystals of zinc sulfate heptahydrate have a characteristic luster and transparency.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is utilized in the manufacturing of pigments and dyes due to its versatile properties.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is hygroscopic, absorbing moisture from the air when exposed.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) decomposes before melting, losing water molecules upon heating.
In the pharmaceutical industry, it may be used in certain formulations and applications.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a common ingredient in some topical preparations for skin conditions.

When dissolved in water, it forms an aqueous solution that can be utilized for various purposes.
Due to its solubility, it is important to store this compound in a cool and dry environment.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is not flammable and does not pose a fire hazard.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) has a density of approximately 1.957 g/cm³ at room temperature.
Zinc sulphate heptahydrate (ZNSO4∙7H2O) is stable under normal storage and handling conditions.

Zinc sulphate heptahydrate (ZNSO4∙7H2O) is a valuable reagent in laboratories for certain chemical reactions and analyses.
The presence of zinc sulfate in water treatment processes helps control algae growth.

As a crystalline substance, it exhibits unique optical properties when examined under a microscope.
Whether in agriculture, industry, or scientific research, Zinc sulfate heptahydrate plays a multifaceted role in various applications.



PROPERTIES


Chemical Name: Zinc sulfate heptahydrate
Chemical Formula: ZnSO₄·7H₂O
Molecular Weight: Approximately 287.56 g/mol
Appearance: Colorless to white crystalline solid
Crystal Structure: Rhombic crystals
Odor: Odorless
Solubility in Water: Highly soluble
pH (1% solution): Approximately 4.0 - 5.0
Melting Point: Decomposes before melting due to loss of water
Density: Approximately 1.957 g/cm³
Boiling Point: Not applicable (decomposition)
Vapor Pressure: Negligible
Refractive Index: Not readily available
Flash Point: Not applicable (non-flammable)
Autoignition Temperature: Not applicable
Flammability: Non-flammable
Explosive Properties: Not explosive
Corrosivity: May corrode metals
Partition Coefficient (Log P): Not readily available
Stability: Stable under normal conditions
Hygroscopicity: Hygroscopic (absorbs moisture from the air)



FIRST AID


Inhalation:

If inhaled, remove the affected person from the contaminated area to fresh air immediately.
Allow the person to rest in a comfortable position and keep warm.
If respiratory distress persists, administer oxygen if trained to do so.
Seek medical attention if symptoms like coughing, difficulty breathing, or irritation persist.


Skin Contact:

In case of skin contact, promptly remove contaminated clothing, including shoes.
Wash the affected area with plenty of soap and water for at least 15 minutes.
If irritation or redness occurs, seek medical attention.
Contaminated clothing should be laundered before reuse.


Eye Contact:

In case of eye contact, flush eyes with plenty of lukewarm water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation persists or if there is evidence of injury.
If contact lenses are present, remove them after the initial flush and continue rinsing.


Ingestion:

If Zinc sulfate heptahydrate is accidentally ingested, do not induce vomiting.
Rinse the mouth thoroughly and drink plenty of water.
Seek immediate medical attention or contact a poison control center.
Provide the medical personnel with information about the ingested substance.


General First Aid Measures:

If someone shows signs of irritation or an allergic reaction after exposure to Zinc sulfate heptahydrate, remove the person from the source of exposure.
Provide comfort and reassurance to the affected individual.
If there are visible signs of chemical burns, rinse the affected area with copious amounts of water.
If the person is unconscious or experiencing difficulty breathing, seek emergency medical assistance immediately.
Do not administer any medication or other substances unless directed by medical professionals.



HANDLING AND STORAGE


Handling Conditions:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and protective clothing.
Use respiratory protection if ventilation is inadequate or if exposure limits are exceeded.

Ventilation:
Work in a well-ventilated area, or use local exhaust ventilation to control airborne concentrations.
Avoid inhaling vapors or mists.

Avoidance of Contact:
Minimize direct skin contact.
If contact occurs, promptly remove contaminated clothing and wash the affected area thoroughly with soap and water.

Hygiene Practices:
Wash hands thoroughly after handling Zinc sulfate heptahydrate.
Do not eat, drink, or smoke while handling the chemical.
Provide eye wash stations and safety showers in areas where Zinc sulfate heptahydrate is handled.

Spill Response:
In case of spills, contain the spill using suitable absorbent materials.
Avoid contact with spilled material, and follow proper cleanup procedures.
Dispose of contaminated materials in accordance with local regulations.

Equipment Handling:
Use appropriate handling equipment and tools to minimize direct contact with Zinc sulfate heptahydrate.
Ensure equipment is properly maintained to prevent leaks or spills.

Transportation:
Transport Zinc sulfate heptahydrate in accordance with local and international regulations.
Use suitable containers that are compatible with the substance.


Storage Conditions:

Storage Location:
Store Zinc sulfate heptahydrate in a cool, dry, and well-ventilated area.
Keep away from incompatible materials and sources of heat.

Temperature Control:
Store at temperatures specified by the manufacturer.
Avoid exposure to extreme temperatures.

Container Type:
Use containers made of materials compatible with Zinc sulfate heptahydrate.
Keep containers tightly closed when not in use.

Protection from Elements:
Protect Zinc sulfate heptahydrate from direct sunlight, moisture, and sources of ignition.

Separation from Incompatibles:
Store Zinc sulfate heptahydrate away from incompatible substances, such as strong acids, strong bases, and oxidizing agents.
Follow compatibility information provided in the SDS.

Handling of Large Quantities:
If handling large quantities, use appropriate storage facilities with containment measures to prevent spills and leaks.
Implement spill response and containment measures.

Labeling:
Ensure that storage containers are clearly labeled with the product name, hazard symbols, and other relevant information.
Clearly mark containers with appropriate hazard warnings.

Security Measures:
Implement appropriate security measures to prevent unauthorized access to the storage area.
Comply with local regulations and facility security protocols.

Emergency Response:
Have emergency response procedures in place, including spill cleanup measures and contact information for relevant authorities.
Train personnel on emergency response protocols.
ZINC SULPHATE MONOHYDRADE
Zinc sulphate monohydrade describes a family of inorganic compounds with the formula ZnSO4(H2O)x.
All are colorless solids.
The most common form includes water of crystallization as the heptahydrate, with the formula ZnSO4·7H2O.
Zinc sulphate monohydrade was historically known as "white vitriol".

CAS: 7446-19-7
MF: H2O4S.H2O.Zn
MW: 181.47
EINECS: 616-096-8

Zinc sulphate monohydrade was historically known as "white vitriol".
Zinc sulfate and Zinc sulphate monohydrade's hydrates are colourless solids.
Zinc sulphate monohydrade can be used in electrolytes for zinc plating.
Zinc sulphate monohydrade can be used as a mordant in dyeing.
Zinc sulphate monohydrade can also be used in medicine as an astringent and emetic.
Zinc Sulfate Monohydrate can be used to supply zinc in animal feeds, fertilizers, and agricultural sprays.

Production, Reactions, Structure
Zinc sulphate monohydrade is produced by treating virtually any zinc-containing material (metal, minerals, oxides) with sulfuric acid.

Specific reactions include the reaction of the metal with aqueous sulfuric acid:

Zn + H2SO4 + 7 H2O → ZnSO4·7H2O + H2
Pharmaceutical-grade Zinc sulphate monohydrade is produced by treating high-purity zinc oxide with sulfuric acid:

ZnO + H2SO4 + 6 H2O → ZnSO4·7H2O
In aqueous solution, all forms of zinc sulfate behave identically.
These aqueous solutions consist of the metal aquo complex [Zn(H2O)6]2+ and SO2−
4 ions.
Barium sulfate forms when these solutions are treated with solutions of barium ions:

ZnSO4 + BaCl2 → BaSO4 + ZnCl2
With a reduction potential of −0.76 V, zinc(II) reduces only with difficulty.

When heated above 680 °C, Zinc sulphate monohydrade decomposes into sulfur dioxide gas and zinc oxide fume, both of which are hazardous.

The heptahydrate is isostructural with ferrous sulfate heptahydrate.
The solid consists of [Zn(H2O)6]2+ ions interacting with sulfate and one water of crystallization by hydrogen bonds.
Anhydrous zinc sulfate is isomorphous with anhydrous copper(II) sulfate.
Zinc sulphate monohydrade exists as the mineral zincosite.
A monohydrate is known.
The hexahydrate is also recognized.

Zinc sulphate monohydrade Chemical Properties
Melting point: decomposes at 238℃ [KIR84]
Density: 1.005 g/mL at 25 °C
Solubility: water: soluble(lit.)
Form: Powder
Color: White
Water Solubility: Soluble in water and alcohol.
Merck: 14,10159
BCS Class: 3
Stability: Stable.
LogP: -1.031 (est)
CAS DataBase Reference: 7446-19-7(CAS DataBase Reference)
EPA Substance Registry System: Zinc sulphate monohydrade (7446-19-7)

The anhydrous Zinc sulphate monohydrade is a colorless rhombohedral crystalline solid; refractive index 1.658; density 3.54 g/cm3; decomposes at 600°C; soluble in water, methanol, and glycerol.
The heptahydrate, ZnSO4•7H2O, is a colorless crystalline solid; metallic taste; rhombohedral crystals; effloresces; refractive index 1.457; density 1.957 g/cm3 at 25°C; melts at 100°C; loses all its water molecules at 280°C; decomposes above 500°C; very soluble in water, 96.5 g/100mL at 20°C; soluble in glycerol, 40 g/100 mL; insoluble in alcohol.
The hexahydrate, ZnSO4•6H2O constitutes colorless monoclinic or tetragonal crystals; density 2.072 g/cm3 at 15°C; loses five water molecules at 70°C; soluble in water.

Uses
Zinc sulphate monohydrade is a special compound fertilizer for improving rapeseed yield.
Zinc sulphate monohydrade may be used in the following studies:
Preparation of rayon, sprays (used in agriculture) and dyes.
As a precipitation reagent during the preparation of sample solution for ultra high pressure liquid chromatographic (UHPLC) analysis.
Preparation of ZnO nanocrystals, via sol-gel incineration technique.
Zinc sulphate monohydrade is used to supply zinc in animal feeds, fertilizers, and agricultural sprays.

Zinc sulphate monohydrade is the raw material for the manufacture of zinc salt and lithopone.
Electrolytic industry is used for cable galvanizing and electrolytic pure zinc.
Zinc sulphate monohydrade is also used to prevent diseases in fruit tree nurseries, wood and leather preservatives, and man-made fiber industries.
Food grade is used as a nutritional supplement (zinc fortifier).
Used in the manufacture of man-made fibers, pesticides, dyes, electroplating and other zinc salts.
Zinc sulphate monohydrade is the raw material for the manufacture of zinc salts and lithopone.
Electrolytic industry is used for cable galvanizing and electrolytic pure zinc.
Zinc sulphate monohydrade is also used to prevent diseases in fruit tree nurseries, wood and leather preservatives, and man-made fiber industries.
Food grade is used as a nutritional supplement (zinc fortifier).

Manufacturing
The main application of the heptahydrate is as a coagulant in the production of rayon.
Zinc sulphate monohydrade is also a precursor to the pigment lithopone.
Zinc sulphate monohydrade is also used as an electrolyte for zinc electroplating, as a mordant in dyeing, and as a preservative for skins and leather.

Nutrition
Zinc sulphate monohydrade is used to supply zinc in animal feeds, fertilizers, toothpaste, and agricultural sprays.
Zinc sulphate monohydrade, like many zinc compounds, can be used to control moss growth on roofs.

Zinc sulphate monohydrade can be used to supplement zinc in the brewing process.
Zinc sulphate monohydrade is a necessary nutrient for optimal yeast health and performance, although it is not a necessary supplement for low-gravity beers, as the grains commonly used in brewing already provide adequate zinc.
Zinc sulphate monohydrade is a more common practice when pushing yeast to their limit by increasing alcohol content beyond their comfort zone.
Before modern stainless steel, brew Kettles, fermenting vessels and after wood, zinc was slowly leached by the use of copper kettles.

A modern copper immersion chiller is speculated to provide trace amounts of zinc; thus care must be taken when adding supplemental zinc so as not to cause excess.
Side effects include "...increased acetaldehyde and fusel alcohol production due to high yeast growth when zinc concentrations exceed 5 ppm.
Excess zinc can also cause soapy or goaty flavors."
Zinc sulphate monohydrade is a potent inhibitor of sweetness perception for most sweet-tasting substances.

Medicine
Main article: Zinc sulfate (medical use)
Zinc sulphate monohydrade is used as a dietary supplement to treat zinc deficiency and to prevent the condition in those at high risk.
Side effects of excess supplementation may include abdominal pain, vomiting, headache, and tiredness.
Zinc sulphate monohydrade is also used together with oral rehydration therapy (ORT) and an astringent.

Production
Zinc sulphate monohydrade is produced as an intermediate in recovering zinc from mineral zinc blende, ZnS (see Zinc, Recovery).
The mineral is roasted at about 1,000°C to form zinc oxide and sulfur dioxide which, on prolonged heating in excess air, converts to zinc sulfate:
2ZnS + 3O2 → 2ZnO + 2SO2
2ZnO + 2SO2 + O2 → 2ZnSO4
In the zinc recovery process, roasted products are leached with sulfuric acid, whereupon zinc oxide is converted to sulfate.
ZnO + H2SO4 → ZnSO4 + H2O
Also, zinc sulfate can be prepared by reacting metallic zinc with dilute sulfuric acid followed by evaporation and crystallization:
Zn + H2SO4 → ZnSO4 + H2

Purification Methods
Crystallise it from aqueous EtOH or dilute H2SO4 below 39o when Zinc sulphate monohydrade forms the heptahydrate, and between 39o and 70o it forms the hexahydrate, and above 70o the monohydrate is stable. The anhydrous salt is obtained from the hydrates by heating at 280o or lower temperatures in a current of dry air.
Zinc sulphate monohydrade decomposes to ZnO and SO2 at 767o.
The solubility of the heptahydrate in H2O is 5.88% at 0o, 61.92% at 30o, 66.61% at 35o and 70.05% at 39o.

Synonyms
Zinc sulfate monohydrate
7446-19-7
16788-42-4
Zinc Sulphate monohydrate
zinc;sulfate;hydrate
Zincaps
ZINCSULFATEMONOHYDRATE
Solvazinc; Solvezink
UNII-PTX099XSF1
PTX099XSF1
Sulfato de zinc monohydratado
Sulfuric acid, zinc salt (1:1), hydrate (8CI,9CI)
Sulfuric acid, zinc salt (1:1), monohydrate
MFCD00149893
Zinc sulfate monohydrate, Zn 35.5%
Zinc sulfate hydrate, Puratronic , 99.999per cent (metals basis)
Zinc sulfate (TN)
Zinc(II)sulfatexhydrate
Zinc sulfate-1-hydrate
Zinc sulfate, monohydrate
zinc(II) sulfate hydrate
Zinc(II) sulfate xhydrate
H2O4S.H2O.Zn
H2-O4-S.H2-O.Zn
ZINC SULFATE [WHO-IP]
DTXSID2035019
RNZCSKGULNFAMC-UHFFFAOYSA-L
Zinc sulfate hydrate, Puratronic?
ZINC SULFATE (MONOHYDRATE)
ZINC SULPHATE (MONOHYDRATE)
ZINC SULFATE MONOHYDRATE [MI]
AKOS015855396
ZINC SULFATE MONOHYDRATE [VANDF]
ZINC SULFATE MONOHYDRATE [WHO-DD]
ZINC SULFATE MONOHYDRATE [WHO-IP]
Zinc sulfate monohydrate, p.a., 98.0%
FT-0653225
D06371
ZINC SULFATE MONOHYDRATE [EP MONOGRAPH]
ZINCI SULFAS MONOHYDRATE [WHO-IP LATIN]
ZINC SULFATE MONOHYDRATE [USP MONOGRAPH]
A838140
Q27286751
Zinc sulfate monohydrate, >=99.9% trace metals basis
Zinc sulfate monohydrate, purum p.a., >=99.0% (KT)
ZINC SULPHATE MONOHYDRATE
Zinc Sulphate Monohydrate is commonly known as Zinc Sulphate (ZnS04 H2O).
Zinc Sulphate Monohydrate is a prime nutrient for plants.
This micro-nutrient is primarily used in maintaining normal health and increased yields;
Zinc Sulphate Monohydrate is applied directly to the crops.


CAS Number: 7446-19-7
EC Number: 231-793-3
Molecular Formula: ZnSO4 · H2O / H2O5SZn


Zinc Sulphate Monohydrate is an inorganic compound and dietary supplement.
Zinc Sulphate Monohydrate is a combination of sulfur and zinc.
This is a herbicide commonly used for algae control.
Zinc is an essential mineral for human, animal and plant nutrition. Zinc is found naturally in food and water.


Zinc Sulphate Monohydrate is an inorganic compound and nutritional supplement.
Zinc Sulphate Monohydrate regulates soil pH.
Zinc Sulphate Monohydrate prevents yellowing of leaves, premature shedding and shrinkage.
Zinc Sulphate Monohydrate increases the plant's resistance to cold.


Zinc Sulphate Monohydrate can be used as a dietary ingredient and as a nutrient.
Zinc is an important antioxidant nutrient.
Zinc Sulphate Monohydrate is necessary for protein synthesis, wound healing, for blood stability, normal tissue function, and aids in the digestion and metabolism of phosphorus.


Zinc Sulphate Monohydrate also governs the contractility of muscles and maintains the body’s alkaline balance.
Zinc Sulphate Monohydrate increases fruit holding in fruit trees.
Zinc Sulphate Monohydrate improves the appearance of the fruit and prevents deformation.


Although the specific role of zinc in plant growth is still being discussed among scientists, it is an important element that plants require to grow properly.
Zinc sulphate Monohydrate is a common participant in the agricultural business, particularly in combating the different levels of zinc deficiency that many types of plants encounter, which can lead to poor plant development and lower output.


Zinc Sulphate Monohydrate is an ionic salt of zinc combined with sulfuric acid that provides a dietary source of zinc.
Zinc is an essential mineral that humans must obtain through diet. Unfortunately, zinc deficiencies are incredibly common, affecting at least 2 billion people worldwide.
A quarter of the world's population is at risk of developing a zinc deficiency, and almost a third of them don’t consume enough through food sources.


Zinc Sulfate Monohydrate is a moderately water and acid-soluble Zinc source for uses compatible with sulfates.
Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal.
Most metal sulfate compounds are readily soluble in water for uses such as water treatment, unlike fluorides and oxides which tend to be insoluble.


Organometallic forms are soluble in organic solutions and sometimes in both aqueous and organic solutions.
Zinc Sulfate Monohydrate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
Zinc sulfate describes a family of inorganic compounds with the formula ZnSO4(H2O)x.


All are colorless solids.
The most common form includes water of crystallization as the heptahydrate, with the formula ZnSO4·7H2O.
Zinc Sulphate Monohydrate was historically known as "white vitriol".
Zinc sulfate and its hydrates are colourless solids.


Zinc Sulphate Monohydrate has varieties in terms of fertilizer quality, feed quality and technical quality.
Zinc Sulphate Monohydrate is a kind of main raw material for producing lithophone and zinc salts.
Zinc Sulfate Monohydrate, also known as white vitriol, is an inorganic, transparent salt with the formula: ZnSO4 * H2O.
Organometallic forms are soluble in organic solutions and sometimes in both aqueous and organic solutions.



USES and APPLICATIONS of ZINC SULPHATE MONOHYDRATE:
Zinc Sulphate Monohydrate is used for spraying, the recommended usage is 5% weight by volume.
Zinc Sulphate Monohydrate is used for solid application, use 5-8 kg/acre.
Zinc Sulphate Monohydrate is used to make Zinc Capsules and Tablets, and Particularly useful for dispersible Zinc Tablets.


Additionally, Zinc Sulphate Monohydrate is used to treat zinc deficiency and prevent high-risk conditions.
Zinc Sulphate Monohydrate increases the amount of product taken per unit area in Pigment in the Agriculture Sector, in the Zinc analysis, in the Pharmaceutical Industry in the extraction of mineral ore, in the Synthetic Fiber Industry in the Beer sector, in the Dye, Leather, Yeast sector in the Feed Industry, Zinc fertilizer production.


Zinc Sulphate Monohydrate regulates soil pH.
Zinc Sulphate Monohydrate prevents yellowing of leaves, premature shedding and shrinkage.
Zinc Sulphate Monohydrate increases the plant's resistance to cold. Increases fruit holding in fruit trees.
Zinc Sulphate Monohydrate improves the appearance of the fruit and prevents deformation.


Zinc Sulphate Monohydrate increases the number of shoots, prevents stunting.
Zinc Sulphate Monohydrate increases the water holding capacity and enables the plant to be affected by drought later.
Zinc Sulphate Monohydrate increases the length and stem thickness of grains.
Zinc Sulphate Monohydrate prevents the yellowing of grass in meadows and pastures, grows fast and provides abundant grass formation.


Zinc Sulfate Monohydrate is a granulated zinc fertiliser for dry application to the soil, either on its own or in blends with other fertilisers.
There are various strategies for applying zinc.
Zinc Sulphate Monohydrate can be applied at a high rate, intended to last several years or at lower rates on an annual basis e.g., each time a crop is sown or, once a year in tree, plantation and vine crops e.g., in the spring which is at the start of the main growing season.


Alternatively, Zinc Sulphate Monohydrate may be applied at lower rates but on a more regular basis in NPK fertiliser blends throughout the growing season, so that the cumulative rate per annum is much the same as where a single application is made
Zinc sulfate monohydrate is used in calico-printing, preserving wood and skins, electrolytes for zinc plating, bleaching paper and clarifying glue.


Zinc Sulphate Monohydrate is also used as a chemical reagent, coagulant in the preparation of rayon, mordant in dyeing and as a zinc source in animal feeds.
In medicine, Zinc Sulphate Monohydrate is used as an astringent and emetic.
Further, Zinc Sulphate Monohydrate is a precursor to the pigment lithopone.


In addition to this, Zinc Sulphate Monohydrate is used to supply zinc in fertilizers, agricultural sprays, in electrolytes for zinc plating and as a mordant in dyeing.
Zinc Sulphate Monohydrate is used Production of Rayon fiber, Micronutrient in fertilizers, Agriculture, Production of paint and varnishes, glues, Titane Dioxide, Zinc Sterate and Zinc-Alkyl-di-thiocarbamate (Fungicide), Rubber As accelerator, flotation of ores, Electroplating and surface treatment, Animal feed.


Zinc Sulphate Monohydrate is used in electrolytes for zinc plating.
Zinc Sulphate Monohydrate is used as an electrolyte for zinc electroplating, as a mordant in dyeing, and as a preservative for skins and leather.


Metallic ions can also be dispersed utilizing suspended or coated nanoparticles and deposited utilizing sputtering targets and evaporation materials for uses such as solar cells and fuel cells.
The main application of Zinc Sulphate Monohydrate is used as feed additive and trace element fertilizer, etc.


Zinc Sulphate Monohydrate is also used in synthetic fiber industry, zinc plating, pesticide, flotation, fungicide, and water purification in agriculture.
Zinc Sulfate Monohydrate can be used in electrolytes for zinc plating. Zinc Sulphate Monohydrate can be used as a mordant in dyeing.
Zinc Sulphate Monohydrate can also be used in medicine as an astringent and emetic.


Zinc Sulfate Monohydrate can be used to supply zinc in animal feeds, fertilizers, and agricultural sprays.
The main application of Zinc Sulphate Monohydrate is as a coagulant in the production of rayon.
Zinc Sulphate Monohydrate is also a precursor to the pigment lithopone.
Zinc Sulphate Monohydrate is used to supply zinc in animal feeds.


Zinc Sulphate Monohydrate is used as in electrolytes for zinc plating, as a mordant in dyeing, as a preservative for skins and leather and in medicine as an astringent and emetic
Zinc Sulphate Monohydrate is also used as laboratory reagent
Zinc Sulphate Monohydrate is used in the agriculture industry as a feed, fertilizer, and spray ingredient.


Zinc Sulphate Monohydrate is also blended with other Fertilizers like SSP / GSSP etc. as it is required by plants in small quantity.
Zinc Sulphate Monohydrate is very effective for treatment of different variety of crops such as cereals, pulses, oilseeds, cotton, sugarcane, vegetables, fruits, potato and many more.
Zinc Sulfate Monohydrate is a moderately water and acid soluble Zinc source for uses compatible with sulfates.


Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal.
Most metal sulfate compounds are readily soluble in water for uses such as water treatment, unlike fluorides and oxides which tend to be insoluble.
Metallic ions can also be dispersed utilizing suspended or coated nanoparticles and deposited utilizing sputtering targets and evaporation materials for uses such as solar energy materials and fuel cells.


Zinc Sulphate Monohydrate is generally immediately available in most volumes.
Zinc Sulphate Monohydrate has high purity, submicron and nanopowder forms may be considered.
Zinc Sulphate Monohydrate is a granulated/crystalline white solid that is an important fertiliser source and animal feed source of zinc and sulfur.


Zinc Sulphate Monohydrate is suitable for application direct to the soil either alone or in multi-nutrient blends, e.g. for row crops, tree crops and sugarcane.
Zinc Sulphate Monohydrate can be used in a variety of industrial applications such as controlling moss growth, in brewing, as an electrolyte in electroplating and as a coagulant in the production of rayon.


-Uses of Zinc Sulphate Monohydrate:
• Zinc Sulphate Monohydrate is used as fertilizer additive for preventing and correcting zinc deciencies in crop.
• Zinc Sulphate Monohydrate increases crop yields.
• Zinc Sulphate Monohydrate regulates pH degree in soil.
• Zinc Sulphate Monohydrate helps leaf to get green colour at early stage and increase in fruit yields.
• Zinc Sulphate Monohydrate increase the durability of the plant against cold weather.
• Fruit makes a good appearance, prevents deformity and good appearance.
• Zinc Sulphate Monohydrate decrease the number of deportation.
• Zinc Sulphate Monohydrate increase the water holding capacity and plant results in no incidence of drought.
• The deviation will decrease the thickness of grain size.


-Cosmetic Uses of Zinc Sulphate Monohydrate:
*antimicrobial agents
*antiplaque agents
*astringents
*oral care agents



USAGE IN THE FORMULATION OF PLANT NUTRITION AND PROTECTION PRODUCTS:
*Zinc Sulphate Monohydrate is used as a supplement in plant protection WG formulations.
*Zinc Sulphate Monohydrate is used as a zinc source in the formulation of liquid and powder plant nutrition products.



AGRICULTURE USES OF ZINC SULPHATE MONOHYDRATE:
*While zinc sulfate monohydrate is used as a raw material in the formulation of plant protection and nutrition products and other industrial applications, it can also be used as a direct fertilizer in agriculture.
*By regulating soil pH, Zinc Sulphate Monohydrate increases the plant's water holding capacity and product productivity.
*Zinc Sulphate Monohydrate prevents the yellowing of the leaves, premature shedding and shrinkage.
*Zinc Sulphate Monohydrate increases the number of shoots and fruit set in fruit trees.
Zinc deficiency is one of the most common micronutrient deficiencies in crops and pastures around the world, causing major losses in crop production and crop quality.



FEED ADDITIVE USES OF ZINC SULPHATE MONOHYDRATE:
*In the feed additive industry, Zinc Sulphate Monohydrate is used as a zinc trace element source in mineral element mixture formulations which is prepared to meet the mineral needs of animals.
Trace elements are important in animal nutrition.
Even in small amounts, they are related to the function of enzymes and hormones.
For example, zinc deficiency causes poor growth, loss of appetite and a poor feed conversion rate.
*Zinc Sulphate Monohydrate also has an important function in defense enzymes.



INDUSTRIAL APPLICATIONS OF ZINC SULPHATE MONOHYDRATE:
*Zinc Sulphate Monohydrate is used as an astringent (blood stopper) in the pharmaceutical industry, in the treatment of acne due to its healing and anti-inflammatory properties, and in the flotation of some metal ores in the mining industry.
*Zinc Sulphate Monohydrate is used as a wood protector and in the manufacture of protective materials.
*Zinc Sulphate Monohydrate is used as an important component of precipitation baths in zinc plating electrolyte and as a mordant in dyeing.



BENEFITS AND USES OF ZINC SULPHATE MONOHYDRATE:
Zinc Sulphate Monohydrate helps in increasing plant growth and development.
If the soil temperature is low, the mineralization process of organic soil slows, resulting in less zinc being produced.
To counteract this impact and promote root development, zinc sulphate is used.
Crops that must grow in sandy soils or soils with minimal organic matter frequently require supplemental zinc sulphate to guarantee that the plants receive adequate nutrients to develop properly.
Zinc Sulphate Monohydrate is simple to administer at planting or during the growing season.
Zinc Sulphate Monohydrate can be easily combined with other fertilisers.



ADVANTAGES OF ZINC SULPHATE MONOHYDRATE:
*Free flowing amorphous powder
*Better solubility
*Better dispersiblity



HOW TO USE ZINC SULPHATE MONOHYDRATE:
Zinc Sulphate Monohydrate should be added to a sprayer or mixing tank that is already filled with fresh water.
Spray Zinc Sulphate Monohydrate directly on the plants before applying any other agrochemical.



TIME OF APPLICATION OF ZINC SULPHATE MONOHYDRATE:
Zinc Sulphate Monohydrate can be used all throughout the year.
Zinc Sulphate Monohydrate should be used at least once a month if you observe Zinc deficiency in your plants.



HOW ZINC SULPHATE MONOHYDRATE WORKS:
Zinc Sulphate Monohydrate works by providing crops with Zinc.
Zinc is necessary for the healthy development and proper growth of plants.



DIFFERENCE BETWEEN ZINC SULPHATE MONOHYDRATE AND HEPTAHYDRATE:
The key difference between zinc sulphate monohydrate and heptahydrate is that zinc sulphate monohydrate has one zinc metal cation and one sulphate anion in association with one water molecule of crystallization whereas zinc sulphate heptahydrate has one zinc metal cation and one sulphate anion in association with seven water molecules of crystallization.

Zinc sulphate or zinc sulphate (different spelling but same substance) is an inorganic substance containing a zinc metal cation and a sulfate anion in its chemical structure.
It is a salt of zinc metal.
This substance is useful as a dietary supplement for the treatment of zinc deficiency in order to prevent any condition that is at high risk.
Moreover, the sulphate molecules having water of crystallization is the most common form of zinc sulphate.
There can be different hydrated forms of this substance, but heptahydrate form is the most common among them.
Furthermore, zinc sulphate and its hydrate forms are all colorless crystal forms.

When considering the applications of zinc sulphate heptahydrate, it is useful as a coagulant in the production of rayon.
Moreover, this substance is important as a precursor for pigment lithopone.
In addition, we can use it in leather and medicine as an astringent and emetic, as a laboratory reagent, as a dietary supplement for animal feed, as a component in fertilizers, and agricultural sprays, etc.

Zinc sulphate monohydrate and heptahydrate are hydrated forms of zinc sulphate, and it’s the number of water molecules of crystallization that make them distinct from each other. The key difference between zinc sulphate monohydrate and heptahydrate is that zinc sulphate monohydrate has one zinc metal cation and one sulphate anion in association with one water molecule of crystallization whereas zinc sulphate heptahydrate has one zinc metal cation and a sulphate anion in association with seven water molecules of crystallization.



WHAT ARE THE SIMILARITIES BETWEEN ZINC SULPHATE MONOHYDRATE AND HEPTAHYDRATE?
Zinc sulphate monohydrate and heptahydrate are inorganic compounds.
Both are salts of zinc metal.
Both are hydrated forms.
These substances appear as colorless crystals.



PHYSICAL and CHEMICAL PROPERTIES of ZINC SULPHATE MONOHYDRATE:
Density: 3.2 g/cm3 (20 °C)
pH value: 4.0 - 5.6 (50 g/l, H₂O, 20 °C)
Bulk density: 500 kg/m3
Solubility: 350 g/l (anhydrous substance)
Appearance: white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 330.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000034 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.031 (est)
Soluble in: water, 7.75e+004 mg/L @ 25 °C (est)
logP: -0.84
pKa (Strongest Acidic): -3
Physiological Charge: -2
Hydrogen Acceptor Count: 4
Hydrogen Donor Count: 0
Polar Surface Area: 80.26 Å2
Rotatable Bond Count: 0

Refractivity: 11.53 m3·mol-1
Polarizability: 5.81 Å3
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
Molecular Weight: 179.5
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 0
Exact Mass: 177.891436
Monoisotopic Mass: 177.891436
Topological Polar Surface Area: 89.6 Ų
Heavy Atom Count: 7
Formal Charge: 0

Complexity: 62.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Physical state: powder
Color: beige
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available

Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water:
Not applicable for inorganic substances
Vapor pressure: No data available
Density: 3,2 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available



FIRST AID MEASURES of ZINC SULPHATE MONOHYDRATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC SULPHATE MONOHYDRATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC SULPHATE MONOHYDRATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC SULPHATE MONOHYDRATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC SULPHATE MONOHYDRATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Dry.
hygroscopic
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC SULPHATE MONOHYDRATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
no information available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Zinc sulfate monohydrate
7446-19-7
16788-42-4
Zinc Sulphate monohydrate
zinc;sulfate;hydrate
Zincaps
ZINCSULFATEMONOHYDRATE
Sulfuric acid, zinc salt (1:1), monohydrate
PTX099XSF1
Sulfuric acid, zinc salt (1:1), hydrate (8CI,9CI)
MFCD00149893
UNII-PTX099XSF1
Gunningite
Sulfato de zinc monohydratado
Zinc sulfate (TN)
Zinc(II)sulfatexhydrate
Zinc sulfate-1-hydrate
Zinc sulfate, monohydrate
zinc(II) sulfate hydrate
Zinc(II) sulfate xhydrate
Zinc Sulfate Monohydrate Powder
DTXSID2035019
Zinc sulfate hydrate, Puratronic?
ZINC SULFATE (MONOHYDRATE)
ZINC SULPHATE (MONOHYDRATE)
Zinc sulfate monohydrate, Zn 35.5%
AKOS015855396
Zinc sulfate monohydrate, p.a., 98.0%
FT-0653225
D06371
A838140
Q27286751
Zinc sulfate monohydrate, >=99.9% trace metals basis
Zinc sulfate monohydrate, purum p.a., >=99.0% (KT)


ZIRCONIUM DIOXIDE
Zirconium dioxide Zirconium dioxide (ZrO2, zirkonyum dioksit), sometimes known as zirconia (not to be confused with zircon), is a white crystalline oxide of zirconium dioxide(zirkonyum dioksit). Its most naturally occurring form, with a monoclinic crystalline structure, is the mineral baddeleyite. A dopant stabilized cubic structured zirconia, cubic zirconia, is synthesized in various colours for use as a gemstone and a diamond simulant.[1] Production, chemical properties, occurrence Zirconia is produced by calcining zirconium dioxide(zirkonyum dioksit). compounds, exploiting its high thermal stability.[2] Structure Three phases are known: monoclinic below 1170 °C, tetragonal between 1170 °C and 2370 °C, and cubic above 2370 °C.[3] The trend is for higher symmetry at higher temperatures, as is usually the case. A small percentage of the oxides of calcium or yttrium stabilize in the cubic phase.[2] The very rare mineral tazheranite, (Zr,Ti,Ca)O2, is cubic. Unlike TiO2, which features six-coordinated titanium in all phases, monoclinic zirconia consists of seven-coordinated zirconium dioxide (zirkonyum dioksit). centres. This difference is attributed to the larger size of the zirconium dioxide (zirkonyum dioksit). atom relative to the titanium atom.[4] Chemical reactions Zirconia is chemically unreactive. It is slowly attacked by concentrated hydrofluoric acid and sulfuric acid. When heated with carbon, it converts to zirconium dioxide (zirkonyum dioksit). carbide. When heated with carbon in the presence of chlorine, it converts to zirconium dioxide (zirkonyum dioksit). tetrachloride. This conversion is the basis for the purification of zirconium dioxide (zirkonyum dioksit). metal and is analogous to the Kroll process. Engineering properties Bearing balls Zirconium dioxide (zirkonyum dioksit). is one of the most studied ceramic materials. ZrO2 adopts a monoclinic crystal structure at room temperature and transitions to tetragonal and cubic at higher temperatures. The change of volume caused by the structure transitions from tetragonal to monoclinic to cubic induces large stresses, causing it to crack upon cooling from high temperatures.[5] When the zirconia is blended with some other oxides, the tetragonal and/or cubic phases are stabilized. Effective dopants include magnesium oxide (MgO), yttrium oxide (Y2O3, yttria), calcium oxide (CaO), and cerium(III) oxide (Ce2O3).[6] Zirconia is often more useful in its phase 'stabilized' state. Upon heating, zirconia undergoes disruptive phase changes. By adding small percentages of yttria, these phase changes are eliminated, and the resulting material has superior thermal, mechanical, and electrical properties. In some cases, the tetragonal phase can be metastable. If sufficient quantities of the metastable tetragonal phase is present, then an applied stress, magnified by the stress concentration at a crack tip, can cause the tetragonal phase to convert to monoclinic, with the associated volume expansion. This phase transformation can then put the crack into compression, retarding its growth, and enhancing the fracture toughness. This mechanism is known as transformation toughening, and significantly extends the reliability and lifetime of products made with stabilized zirconia.[6][7] The ZrO2 band gap is dependent on the phase (cubic, tetragonal, monoclinic, or amorphous) and preparation methods, with typical estimates from 5–7 eV.[8] A special case of zirconia is that of tetragonal zirconia polycrystal, or TZP, which is indicative of polycrystalline zirconia composed of only the metastable tetragonal phase. Uses High translucent Zirconia bridge layered by porcelain and stained with luster paste The main use of zirconia is in the production of hard ceramics, such as in dentistry,[9] with other uses including as a protective coating on particles of titanium dioxide pigments,[2] as a refractory material, in insulation, abrasives and enamels. Stabilized zirconia is used in oxygen sensors and fuel cell membranes because it has the ability to allow oxygen ions to move freely through the crystal structure at high temperatures. This high ionic conductivity (and a low electronic conductivity) makes it one of the most useful electroceramics.[2] Zirconium dioxide (zirkonyum dioksit). is also used as the solid electrolyte in electrochromic devices. Zirconia is a precursor to the electroceramic lead zirconate titanate (PZT), which is a high-K dielectric, which is found in myriad components. Niche uses The very low thermal conductivity of cubic phase of zirconia also has led to its use as a thermal barrier coating, or TBC, in jet and diesel engines to allow operation at higher temperatures.[10] Thermodynamically, the higher the operation temperature of an engine, the greater the possible efficiency. Another low thermal conductivity use is a ceramic fiber insulation for crystal growth furnaces, fuel cell stack insulation and infrared heating systems. This material is also used in dentistry in the manufacture of 1) subframes for the construction of dental restorations such as crowns and bridges, which are then veneered with a conventional feldspathic porcelain for aesthetic reasons, or of 2) strong, extremely durable dental prostheses constructed entirely from monolithic zirconia, with limited but constantly improving aesthetics.[11] Zirconia stabilized with yttria (yttrium oxide), known as yttria-stabilized zirconia, can be used as a strong base material in some full ceramic crown restorations.[12] Transformation toughened zirconia is used to make ceramic knives. Because of the hardness, ceramic-edged cutlery stays sharp longer than steel edged products.[13] Due to its infusibility and brilliant luminosity when incandescent, it was used as an ingredient of sticks for limelight.[citation needed] Zirconia has been proposed to electrolyze carbon monoxide and oxygen from the atmosphere of Mars to provide both fuel and oxidizer that could be used as a store of chemical energy for use with surface transportation on Mars. Carbon monoxide/oxygen engines have been suggested for early surface transportation use as both carbon monoxide and oxygen can be straightforwardly produced by zirconia electrolysis without requiring use of any of the Martian water resources to obtain hydrogen, which would be needed for the production of methane or any hydrogen-based fuels.[14] Zirconia can be used as photocatalyst [15] since its high band gap (~ 5 eV)[16] allows the generation of high energetic electrons and holes. Some studies demonstrated the activity of doped zirconia (in order to increase visible light absorption) in degrading organic compounds [17][18] and reducing Cr(VI) from wastewaters.[19] Zirconia is also a potential high-k dielectric material with potential applications as an insulator in transistors. Zirconia is also employed in the deposition of optical coatings; it is a high-index material usable from the near-UV to the mid-IR, due to its low absorption in this spectral region. In such applications, it is typically deposited by PVD.[20] In jewelry making, some watch cases are advertised as being "black zirconium dioxide(zirkonyum dioksit). ".[21] In 2015 Omega released a fully ZrO2 watch named "The Dark Side of The Moon" [22] with ceramic case, bezel, pushers and clasp, advertising it as four times harder than stainless steel and therefore much more resistant to scratches during everyday use. Diamond simulant Main article: Cubic zirconia Brilliant-cut cubic zirconia Single crystals of the cubic phase of zirconia are commonly used as diamond simulant in jewellery. Like diamond, cubic zirconia has a cubic crystal structure and a high index of refraction. Visually discerning a good quality cubic zirconia gem from a diamond is difficult, and most jewellers will have a thermal conductivity tester to identify cubic zirconia by its low thermal conductivity (diamond is a very good thermal conductor). This state of zirconia is commonly called cubic zirconia, CZ, or zircon by jewellers, but the last name is not chemically accurate. Zircon is actually the mineral name for naturally occurring zirconium dioxide (zirkonyum dioksit). silicate (ZrSiO4). Zirconium dioxide(zirkonyum dioksit). Kristallstruktur Zirconium dioxide(zirkonyum dioksit). (IV)-oxid.png Names IUPAC names Zirconium dioxide(zirkonyum dioksit). Zirconium dioxide(zirkonyum dioksit). Other names Zirconia Chemical formula ZrO2 Other anions Zirconium dioxide(zirkonyum dioksit). Other cations Titanium dioxide Hafnium dioxide Oxide Ceramics – Zirconium dioxide (zirkonyum dioksit). (ZrO2) The All-purpose Construction Material Unlike other ceramic materials, zirconium dioxide (ZrO2 –also known as zirconia, (zirkonyum dioksit).) is a material with very high resistance to crack propagation. Zirconium dioxide (zirkonyum dioksit). ceramics also have very high thermal expansion and are therefore often the material of choice for joining ceramic and steel. Worth knowing: Properties of Zirconium dioxide (ZrO2, (zirkonyum dioksit).) High thermal expansion (α=11 x 10-6/K, similar to some types of steel) Excellent thermal insulation/low thermal conductivity (2.5 to 3 W/mK) Very high resistance to crack propagation, high fracture toughness (6.5 to 8 MPam1/2) Ability to conduct oxygen ions (used for the measurement of oxygen partial pressures in lambda probes) Another outstanding property combination is the very low thermal conductivity and high strength. In addition, some types of zirconium dioxide (zirkonyum dioksit). ceramics can conduct oxygen ions. Components made from this material are significantly more expensive than components made of alumina ceramics. Zirconium dioxide (zirkonyum dioksit). ceramics are used, among Zirconium Dioxide (Zirconia, (zirkonyum dioksit).): Properties, Production and Applications Zirconium dioxide(zirkonyum dioksit), also known as zirconia and zirconium dioxide(zirkonyum dioksit)., is a crystalline metal oxide that has found its way into the ceramics industry. It is characterised by its high thermal resistivity, mechanical resistance, and abrasive properties. First used in the medical industry in 1969, zirconia has demonstrated exceptional biocompatibility, with good tribological properties, good aesthetic, and high mechanical properties. It is used quite pre-eminently in dental procedures, as in zirconia crowns and zirconia-based implant abutments [1]. One of its most popular forms is cubic zirconia, a cubic crystalline compound that is colourless and mechanically tough. Because of its optically flawless property, it serves as a low-cost alternative to diamonds in the jewellery industry. Zirconium dioxide (zirkonyum dioksit) . should not be confused with zircon (or zirconium dioxide silicate(zirkonyum dioksit).), a mineral that is also used in the ceramics industry and refractories. What zirconia is Properties of zirconia How zirconia is produced and processed The different application areas where zirconia excels Dental drilling process. What is zirconia? Zirconia is a crystalline solid that is white in colour, but can be produced in different colours to be used as an alternative gemstone to diamond or as ceramic dental crowns in medical applications. Naturally, it occurs as the translucent (sometimes transparent) mineral baddeleyite, a rare mineral that has a monoclinic prismatic crystal structure; i.e. a mineral having unequal vectors. Also known as “ceramic steel”, this oxide of zirconium dioxide (zirkonyum dioksit). is chemically inert and is considered as one of the highly auspicious restorative materials, due to its excellent mechanical properties. Out of all advanced ceramic materials, zirconia has the highest toughness and strength at room temperature. At high temperatures, zirconia may go through substantial change in volume during phase transformation. As a result, it is difficult to obtain stable zirconia products during sintering, which is why stabilisation of zirconia is generally required. Partially stabilised zirconia (PSZ) adds to the exceptional mechanical properties and chemical inertness a high level of chemical stability, even in harsh environments. It is used as a substitute for alumina in biomedical applications such as dental implants, thanks to its superior mechanical properties, and is comparable with teeth in terms of mechanical strength [2]. Other relative materials to PSZ include yttria-stabilised zirconia (YSZ), calcia-stabilised zirconia (CSZ), and magnesia-stabilised zirconia (MSZ). Properties of zirconia Zirconia’s exceptional strength, toughness, biocompatibility, high fatigue and wear resistance render it optimal for dental applications. Zirconium dioxide (Zr, (zirkonyum dioksit)), in particular, is in fact one of the two most commonly used metals in dental implants, alongside titanium, as they both show very good physical and chemical properties and they allow the growth of osteoblasts, the cells that actually form bones [3]. Here’s a list of zirconia’s most prominent physical and chemical properties. Notice how these properties are high enough to allow zirconia to be an effective material for many applications, especially for refractory and dentistry purposes. High mechanical resistance Zirconium dioxide (zirkonyum dioksit) is highly resistant to cracking (including further development of cracks) and mechanical stress. Other outstanding mechanical properties of zirconia are shown in the table below. High temperature resistance and expansion With a melting point of 2700ºC and a thermal expansion coefficient of 1.08×10-5 K-1, zirconium dioxide (zirkonyum dioksit) is widely known for its high resistance to heat. This is the reason why the compound has found a wide variety of uses in refractories and high-temperature industries. Here are the different temperature ranges of melting point for zirconia, based on its temperature-dependent forms. Upon heating, however, zirconia may undergo phase change, especially in its tetragonal form, where internal stresses arise, and cracks begin to develop. In order to resolve and correct this weakness, stabilisers such as yttria are added to make up a more stable yttria partially stabilised zirconia (or yttria tetragonal zirconia polycrystal, YTZP) [4]. Low thermal conductivity Zirconium dioxide (zirkonyum dioksit) has a thermal conductivity of 2 W/(m·K), which makes it perfect for situations where heat needs to be contained. Chemical resistivity The substance is chemically inert and unreactive, which works in industries that make use of several chemicals during processing. However, the compound dissolves in concentrated acids such as sulfuric or hydrofluoric acid. Production and processing of zirconia Production of zirconium dioxide (zirkonyum dioksit) may result in the aforementioned three possible phases depending on the temperature: monoclinic, tetragonal, and cubic. This unique property of zirconium dioxide (zirkonyum dioksit) provides flexibility of use in a wide variety of purposes and industries. Zirconia is produced through thermal treatment, or thermal dissociation, although doing it in its pure form may cause abrupt phase changes that may crack or fracture the material. That is when doping with stabilisers, such as magnesium oxide, yttrium oxide, and calcium oxide, is applied to keep the structure intact. This thermal process is also referred to as calcination, where heating to high temperatures is performed within an oxygen or air medium. Zirconia can also be produced by decomposing zircon sand via fusion with compounds such as calcium carbonate, calcium oxide, sodium carbonate, magnesium oxide, and sodium hydroxide (also known as caustic soda). Chlorination of zircon also leads to the production of zirconia, where the resulting zirconium dioxide (zirkonyum dioksit) tetrachloride is calcined at a high temperature (~900ºC), producing a commercial grade of zirconia. Another way is to dissolve the collected zirconium dioxide (zirkonyum dioksit) tetrachloride in water to form crystallised zirconyl chloride. This resultant is then thermally treated at a high temperature to produce high-purity zirconia [5]. High-purity zirconium dioxide (zirkonyum dioksit) is the precursor for producing zirconium dioxide (zirkonyum dioksit) powders, through the reduction of ZrO2 with calcium hydrate. This calciothermic process is prepared under an argon atmosphere at continuous heat at about 1000°C. Applications of zirconium dioxide(zirkonyum dioksit) Zirconia’s high mechanical properties, chemical inertness, high-temperature stability, corrosion resistance, and high quality have put this ceramic steel on the radar in many industries and application areas. Many products of today, ranging from refractory to medical products, pigments, electronics, coatings, and ceramics, have been based on zirconia due to its superior characteristics and advantages as compared to other materials. Some of the typical applications of zirconia include dies for hot metal extrusion, oxygen sensors, membranes in fuel cells, deep well valve seats, and marine pump seals. Here is a list of some of zirconia’s most common applications areas and uses. Ceramics The mechanical strength and resistance of zirconium dioxide (zirkonyum dioksit) makes it a suitable component for ceramic manufacturing. This includes ceramic knives, which are noticeably tougher than steel-edged cutlery due to the high hardness factor of zirconia. Refractory purposes Due to its high thermal resistance, zirconium dioxide (zirkonyum dioksit) is used as a component in crucibles, furnaces, and other high-heat environments. In addition, zirconium dioxide (zirkonyum dioksit) boosts the fireproof properties of ceramics. Refractory bricks and armour plates are examples of zirconia-based refractory applications. Furthermore, when added to melted quartz, zirconia can be used to produce siloxide glass, a harder and more stress resistant glass than quartz opaque glass [6]. Zirconia can also be added to aluminium oxide to be used in components for steel casting process. Thermal barrier coating (TBC) Zirconium dioxide (zirkonyum dioksit) is applied as a coating for jet engine components which are exposed to high temperatures. This is made possible through the compound’s low thermal conductivity and high heat resistance. Studies have confirmed the effectiveness of zirconium dioxide (zirkonyum dioksit) for TBC applications, as long as the material is applied properly and uniformly. Dental industry Due to its biocompatibility, good aesthetics, and high mechanical properties, one of the most popular uses of zirconium dioxide (zirkonyum dioksit) is in dentistry, mainly in dental restorations for bridges, crowns, and feldspar porcelain veneers and dental prostheses. Yttria-stabilized zirconium dioxide (zirkonyum dioksit) is also instrumental in producing near-permanent zirconia crowns. Scratch resistant and abrasive material With its elevated mechanical stability and abrasion resistance, zirconia is being used as an abrasive material. It is also useful as a protective layer for mechanical parts, due to the compound’s resistance to scratches and mechanical stress. Oxygen-rich systems While other materials may experience oxidation and compromise its integrity, zirconium dioxide (zirkonyum dioksit) is stable in the presence of oxygen. In fact, it is being used in fuel cell membranes and oxygen sensing mechanisms even at elevated temperatures. Zirconium dioxide (ZrO2, (zirkonyum dioksit)), which is also referred to as zirconium dioxide (zirkonyum dioksit) or zirconia, is an inorganic metal oxide that is mainly used in ceramic materials. Zirconium dioxide (zirkonyum dioksit) succeeds zirconium dioxide (zirkonyum dioksit) as the compound of the element zirconium dioxide (zirkonyum dioksit) that most frequently occurs in nature. It is a heavy metal of which 0,016 % is found in the earth crust and which, thus, occurs more frequently than the elements chlorine and copper. Its great hardness, low reactivity, and high melting point have made it the oldest mineral that can be found on the earth. Zirconium dioxide (zirkonyum dioksit) does not occur massively but is bound in minerals, mainly in zircon (ZrSiO4). Zircon is also known as a precious stone whose color may vary from colorless white to brown, green, etc., depending on the traces of impurities. Due to their high optical density, zircon (and zirconia) gems have high refraction indices. Provided they are pure and large enough, they are suited, therefore, as (cheaper) substitutes for diamonds. None of the natural isotopes of zircon is radioactive. Yet, since zircon is relatively often impurified with uranium oxides and other radioactive substances such as thorium salts, it is responsible for much of the natural radioactive radiation. Geological age determination through radioactive dating, for example, makes use of such impurities. Zirconium dioxide (zirkonyum dioksit) is the most important zirconium dioxide (zirkonyum dioksit) compound which due to its properties is used in various products. In nature, ZrO2 occurs in the mineral form as baddeleyite, a modification in monoclinic crystal lattices (which is often found as weathered grit in gravel). Zirconium dioxide (zirkonyum dioksit) is non-magnetic and highly resistant against acids, alkaline lyes, and exogenous (chemical, thermal, and mechanical) influences. Zirconium dioxide (zirkonyum dioksit) has a high thermal stability. It does not melt below 2680 °C, which is why it is used in high-temperature ceramics such as crucibles or furnaces. Since, in addition, it has a high mechanical stability and is very resistant to abrasion, it serves to e.g., improve the properties (especially the scratch resistance) of varnishes and coatings applied as top coats to automobiles, or as finishes to parquets and furniture. Zirconium dioxide (zirkonyum dioksit) is also found in varnishes for electronic items, in nail polishes, in ink jet printer’s inks, and other products. Besides, it is known as an abrasive and is found (like titanium dioxide) as a white pigment in porcelain. Moreover, hip joint endoprostheses and other high-performance medical ceramics benefit from the advantages of zirconium dioxide(zirkonyum dioksit). Dentistry makes use of its special properties when manufacturing corona frames and bridge frames, tooth root studs, and metal-free dental implants. Zirconium dioxide (zirkonyum dioksit) is the most widely used oxide ceramic next to aluminium oxide. Thanks to its electrolytic conductivity, it was used as early as in 1897 in the incandescent bodies (ceramic rods) of the Nernst lamp, an electrically powered incandescent lamp invented by the German physicist and chemist Walther Nernst. Zirconium dioxide (zirkonyum dioksit) is not self-inflammable as nanometer-sized powder. Also as a mixture with air (dust) under the influence of an ignition source, it is not inflammable, so there is no possibility of a dust explosion. NanoCare Data Sheets Zirconium Dioxide (zirkonyum dioksit) data sheet No.1 Zirconium Dioxide (zirkonyum dioksit) data sheet No.2 Zirconium Dioxide (zirkonyum dioksit) data sheet No.3 a white crystalline oxide also known as zirconia, the cubic crystalline form used in jewelry is rarely found in nature. Oxide compounds are not conductive to electricity. However, certain perovskite structured oxides are electronically conductive finding application in the cathode of solid oxide fuel cells and oxygen generation systems. They are compounds containing at least one oxygen anion and one metallic cation. They are typically High Purity (99.999%) Zirconium dioxide (ZrO2, (zirkonyum dioksit)) Powderinsoluble in aqueous solutions (water) and extremely stable making them useful in ceramic structures as simple as producing clay bowls to advanced electronics and in light weight structural components in aerospace and electrochemical applications such as fuel cells in which they exhibit ionic conductivity. Metal oxide compounds arebasic anhydrides and can therefore react with acids and with strong reducing agents in redox reactions. Zirconium dioxide(zirkonyum dioksit) is also available in pellets, pieces, powder, sputtering targets, tablets, and nanopowder (from American Elements' nanoscale production facilities). Zirconium dioxide (zirkonyum dioksit) is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. Additional technical, research and safety (MSDS) information is available.
ZIRCONIUM OCTOATE
Bromide of Zinc; 溴化锌; Zinc dibromide; Hydrobromic Acid Zinc Salt; Bromide Salt of Zinc; Zinc bromide CAS NO: 7699-45-8
ZIRCONIUM SILICATE
ZIRCONIUM SILICATE = ZIRCON = ZIRCONIUM ORTHOSILICATE


CAS Number: 10101-52-7
EC Number: 233-252-7
MDL Number: MFCD00085353
Molecular Formula: ZrSiO4 or O4SiZr



Zirconium silicate, also zirconium orthosilicate, ZrSiO4, is a chemical compound, a silicate of zirconium.
Zirconium silicate occurs in nature as zircon, a silicate mineral.
Powdered Zirconium silicate is also known as zircon flour.
Zirconium silicate is usually colorless, but impurities induce various colorations.


Zirconium silicate is insoluble in water, acids, alkali and aqua regia.
Zirconium silicate's hardness is 7.5 on the Mohs scale.
As of 1995, the annual consumption of zirconium silicate was nearly 1M tons.
Zirconium Silicate is generally immediately available in most volumes.
Ultra high purity, high purity, submicron and nanopowder forms may be considered.


Zirconium silicate (or zircon) is extremely stable (refractory, hard, dense).
Large quantities of Zirconium silicate are used by the tile, sanitaryware and tableware industries (to opacify glazes).
Zirconium silicate sand (which is milled to produce zirconium silicate powders), is a major source for the production of zirconia ZrO2.
Zirconium silicate is a ceramic material noted for Zirconium silicate's high hardness of 7.5 on the Mohs scale.


Zirconium silicate is a material with refractory properties and a high resistance to corrosion and alkalis.
Zirconium silicate (ZrSiO4), refractive index 1.93-2.01, good chemical stability, and high temperature resistance, not affected by ceramic firing atmosphere, significantly improve embryo and glaze bonding, improve the hardness of glaze.
Zirconium Silicate, (ZrSiO4) is a chemical compound, a silicate of zirconium.


Zirconium silicate occurs in nature as the zircon, a silicate mineral.
Zirconium silicate has reasonable distribution, high whiteness, low reflecting property and strong covering power, very good distribution in all kinds of ceramic glaze, good opacification and flowability.
Zirconium silicate can replace expensive stannic oxide and zirconium dioxide.
Zirconium silicate has strong wear resistance and whitening effect.


Zirconium silicate is a colorless tetragonal crystals (when pure); presence of impurities forms various colors; density 4.56 g/cm3; hardness 7.5 Mohs; dissociates to ZrO2 and SiO2 above 1,540°C; melts at 2,550°C; insoluble in water, acids, aqua regia, and alkalies; inert in most chemicals.
Zirconium silicate is used as an additive to glass, in ceramic tiles, in ultrafiltration membranes, and as a dental abrasive.
Zirconium silicate is a naturally occurring silicateof zirconium, ZrSiO4, used as a gemstone.


The colour depends in small amounts of other metals and may bered, brown, yellow, or green.
Redgem-quality zircon is sometimes called jacinth; gem-quality Zirconium silicate with other colours are called jargoons.
There is also a naturally occurring colourless variety.
Zircongems can be given other colours, ormade colourless, by heat treatment.
The colourless varieties (either naturalor treated) are sometimes calledMatura diamonds (after Matura in SriLanka).


The name 'zircon' is often erroneously applied to a synthetic formof the oxide cubic zircona, which isused as a diamond substitute.
Zirconium Silicate Zr(SiO4) is high refractive index 1.93-2.01, chemical stability, is a kind of high quality.
Depending on the application, Zirconium silicate sand may be calcined at a high temperature giving a stabilised product.
At one of the most sophisticated plants in Europe, Zirconium silicate is processed and milled to the most stringent grading and particle sizes required.


A range of Zirconium silicate materials is available.
However, for special applications, alternative particle sizes can be processed.
Zirconium silicate, also zirconium orthosilicate, (ZrSiO4) is a chemical compound, a silicate of zirconium.
Zirconium silicate is usually colorless, but impurities induce various colorations.
Zirconium silicate is insoluble in water, acids, alkali and aqua regia.


Zirconium silicate occurs in nature as mineral zircon.
Zircon is a mineral belonging to the group of nesosilicates.
Zirconium silicate's corresponding chemical formula is ZrSiO4.
Zirconium silicate is a transparent, translucent, or opaque mineral, composed chiefly of zirconium silicate, ZrSiO4, and crystallizes in the tetragonal system.


Zirconium silicate can be made by fusion of SiO2 and ZrO2 in an arc furnace, or by reacting a zirconium salt with sodium silicate in an aqueous solution.
Zirconium silicate has recently attracted increasing interest due to its outstanding properties as a gate dielectric.
Zirconium silicate is thermally stable with Si and a good barrier against oxygen diffusion.
Zirconium silicate thin films have been deposited by sputtering and atomic layer deposition ALD.


Optimization of the ALD process to deposit zirconium silicate films was demonstrated with a precursor combination of ZrCl4 and TBOS.
Zirconium silicate (ZrSiO4) is one of the most important compounds obtained from zircon sands; baddeleyite is a natural form of zirconia (ZrO2).
Zirconium silicate sands are produced by different branches of industry for several applications in the ceramic industry.
This production can be made by different milling processes: dry milling and wet milling.


Polyelectrolyte allows formation of flocs for the separation of zirconium silicate solids from the water.
At present, Australia, South Africa, United States, Ukraine, India, China, Brazil and Sri Lanka are the largest exporters of zirconium minerals, in 1992 they supplied about 99% of the world production.
In Italy, zirconium minerals are widely used and most of the national demand, currently estimated at around 60 - 65 ktons, goes into the ceramics market.


The zirconium minerals are used in the Italian ceramic industry for the production of ceramic colours, glazes, tiles and sanitary and table ware.
The zirconium-silicate mineral zircon is produced as a coproduct from the mining and processing of heavy minerals.
Eudialyte and gittinsite are zirconium silicate minerals that have a potential for zirconia production. Identified world resources of zircon exceed 60 million tons.


First principles density functional theory calculations are carried out to investigate the scaling trends of band offsets at model silicon/zirconium silicate interfaces.
Zirconium silicate is found in nature associated with acidic igneous rocks, from which zircon sand form through weathering.
Australia is the world’s largest producer of zircon (zirconium silicate—ZrSiO4), chiefly in the form of heavy mineral sands.
Zirconium Silicate is a powder that is water insoluble.


Zirconium silicate is often colorless, although Zirconium silicate can also be brown, pale yellow, light red, green, or gray in color.
The number 40 is the atomic number of Zirconium silicate.
Zirconium silicate's melting point is 1540°C and Zirconium silicate has a specific gravity of 6.4. ZrSiO4 is a zirconium silicate chemical compound.
Zirconium silicate has a molecular weight of 183.31.


Zirconium silicate has a density of 4.56 gm/cm3.
Zirconium silicate is the main component of natural zircon.
Zirconium silicate is hard like quartz.
Zirconium silicate is chemical stability.


Above 1540 ℃, Zirconium silicate starts to decompose into zirconium dioxide and silica.
Zirconium Silicate is insoluble in water, acid, aqua regia and alkali.
Zirconium Silicate Powder is a high-quality product with a good refractive index of 1.93-2.01.
Zirconium silicate also produce grinding media for milling.
The highest purity Zirconium Silicate can be found in deposits close to the American, Australian and South African coasts.


Zirconium silicate sand is separated from other minerals by ore dressing techniques during which strict controls are made to ensure the quality of the final product.
Zirconium silicate is an occurs in nature as the mineral, zircon.
Zirconium silicate is a ceramic material, resistant to alkaline environments and available in two different granulometry grades.
Zirconium silicate stabilises the friction coefficient at high temperatures.


Individual Zirconium silicate particles are angular, very hard and refractory and amazingly, they do not readily dissolve into glaze melts even when ball milled to exceedingly small particle sizes.
Zircon is the generic name for zirconium silicate, the trade names are different.
The refractive index of Zirconium silicate is high (particularly with micronized zircon, size less than 5 microns).
Notwithstanding this, some sources list Zirconium silicate as a source of SiO2 in glazes (meaning that it does decompose).


This view is plausible since smaller amounts of Zirconium silicate do not opacify glazes, in fact, Zirconium silicate are purposely added to raise refractive index to encourage transparency and high gloss.
That means Zirconium silicate dissolves when percentages are low and precipitates to opacify when they are higher.
Interestingly, Zirconium silicate dissolves so well at low percentages that are is sometimes added to clear glazes to make them more transparent (because Zirconium silicate has a high refractive index).



USES and APPLICATIONS of ZIRCONIUM SILICATE:
The major applications of Zirconium silicate exploit Zirconium silicate's refractory nature and resistance to corrosion by alkali materials.
Two end-uses are for enamels, and ceramic glazes.
In enamels and glazes Zirconium silicate serves as an pacifier.
Zirconium silicate can be also present in some cements.
Another use of Zirconium silicate is as beads for milling and grinding.


Thin films of Zirconium silicate and hafnium silicate produced by chemical vapor deposition, most often MOCVD, can be used as a high-k dielectric as a replacement for silicon dioxide in semiconductors.
Zirconium silicate (or zircon) is extremely stable (refractory, hard, dense).
Large quantities of zircon are used by the tile, sanitaryware and tableware industries.


Zirconium silicates have also been studied for potential use in medical applications.
For example, ZS-9 is a zirconium silicate that was designed specifically to trap potassium ions over other ions throughout the gastrointestinal tract.
Because of Zirconium silicate's high thermal stability Zirconium silicate is also employed in making various hi-tech refractories, porcelain bodies, coatings and materials, even dentures.
Calcined alumina is an alternative in fabricating super refractories but it has much higher thermal expansion and greater heat conductivity.


Zirconium silicate is widely used in the production of various architectural ceramics, sanitary ceramics, daily-use ceramics, first-class handicraft ceramics and so on because of its good chemical stability.
Zirconium silicate can significantly improve the bonding performance of ceramic glazes and improve the hardness of ceramic glazes.
Zirconium silicate is further used in the production of color picture tubes, emulsified glass and enamel glaze in the glass industry.
Zirconium silicate has a high melting point: 2500 degrees Celsius, so Zirconium silicate is also widely used in refractory materials, glass furnace zirconium ramming materials, castables, and spray coatings.


Zirconium silicate Powder is a high-quality and inexpensive opacifier with a high refractive index of 1.93-2.01 and chemical stability.
Zirconium silicate is widely used in the production of various ceramics.
Besides, Zirconium silicate Powder has a high melting point, so Zirconium silicate is also widely used in refractory materials, zirconium ramming materials for glass furnaces, casting materials and spray coatings.


Zirconium Silicate Powder can be applied in the following fields:
Ceramics, Refractory materials, Zirconium ramming materials, Casting materials, and Spray coatings
Zirconium silicate produced by milling the natural zircon sand is widely used as an opacifier of wall and floor tiles, sanitarywares and pottery.
Zirconium silicate Powder (ZrSiO4 Powder) is a very important material that is widely used in various industries.


Zirconium silicate can be used for high quality construction materials and pottery with its uniform particle size and quality, showing superior emulsion effects, incresed mechanical and thermal strength and resistance to chemicals, as well as color stability.
Zirconium silicate is also used in production of some ceramics, enamels, and ceramic glazes. In enamels and glazes it serves as an pacifier.
Zirconium silicate can be also present in some cements.
Another use of Zirconium silicate is as beads for milling and grinding. -Thin films of Zirconium silicate and hafnium silicate produced by chemical vapor deposition.



In a non-crazed glaze, the presence of sufficient Zirconium silicate can reduce thermal expansion enough that there is a danger of shivering (the glaze formulation may need to be adjusted to accommodate, e.g. more Zirconium silicate lowers glaze thermal expansion).
It is best to exclude the chemistry of the Zirconium silicate materials from participation in glaze chemistry calculations, treating Zirconium silicate simply as an addition (then take into consideration its effect on glaze properties on a physical rather than chemical level).
Zirconium silicate is widely applied to glaze and frit industry.


Zirconium silicates have also been studied for potential use in medical applications.
For example, ZS-9 is a zirconium silicate that was designed specifically to trap potassium ions over other ions throughout the gastrointestinal tract.
Zirconium silicate is used for manufacturing refractory materials for applications where resistance to corrosion by alkali materials is required.


Zirconium silicate is used in refractories, ceramics, glazes, cements, coatings for casting molds, polishing materials, gemstones, and cosmetics.
Zirconium silicate is also used as a catalyst and silicone rubber stabilizer.
Zirconium silicate is used as a refractory, abrasive, and to make ceramic glazes and enamels; Also used in the steel and glass industries and in foundries to make molds.


Zirconium silicate is applied in glass additive, sanitary ware, tiles and other ceramic glaze, micro granule.
Zirconium silicate is used for manufacturing refractory materials and foundry casting, also used in glass additive, sanitary ware, tiles and other ceramic glaze as an opacifier.
Zirconium silicate (ZrSiO4) is one form of the mineral whose crystals when polished are known as cubic zircons, which resemble diamond gemstones.


Zirconium silicate is widely used in ceramic production because of its good chemical stability, so Zirconium silicate is not affected by ceramic firing atmosphere, and can significantly improve the bonding properties of ceramic glaze and increase the hardness of ceramic glaze.
Zirconium silicate has also been further applied in the production of color picture tubes in television industry, emulsified glass and enamel glaze in glass industry. The MELTING POINT OF ZIRCONium SILICATE IS HIGH: 2500 degrees Celsius.
Zirconium silicate is also widely used in refractory materials, glass kiln Zirconium ramming materials, castables, spray coatings


Zirconium silicate is widely used in all kinds of building ceramics, sanitary ceramics, daily ceramics, first-class handicraft ceramics production, in the processing and production of ceramic glaze, wide range of use, large dosage.
Zirconium silicate is finely-milled zircon provides high whiteness and opacity in ceramic glazes and porcelain bodies for the various ceramic products, such as ceramic tile, sanitaryware, roofing tile, table ware and so on.
Zirconium silicate is used for manufacturing refractory materials for applications where resistance to corrosion by alkali materials is required.


Thin films of zirconium silicate and hafnium silicate produced by chemical vapor deposition, most often MOCVD, can be used as a high-k dielectric as a replacement for silicon dioxide in semiconductors.
Zirconium Silicate is also used in production of some ceramics, enamels, and ceramic glazes.
Zircon is recovered from heavy mineral sands and is used largely for its thermal properties in the fields of ceramics refractories and foundry uses.


Some experimental tests were carried out in a pilot-plant scale in order to assess the viability of different membrane processes in the treatment of the effluent from a zirconium silicate production industry.
Selective Laser Sintering of zirconium silicate as a ceramic material used for investment casting shells and cores is an attractive alternative to the conventional, time-consuming way of producing these shells from a wax master.


Zirconium Silicate is reported by Kleber and Putt (1986) as being used in chewing gum and in a dental prophylaxis paste.
Zirconium silicate, ZrSiO4, is a natural mineral used various applications as a refractory bulk material.
Zirconium silicate is an excellent feedstock for the plasma spraying of protective coatings and free-standing bodies.
Zirconium Silicate has different kinds of applications in the ceramic industry, including as a whiteness and opacity booster.


Zirconium Silicate’s also used as a raw material in ceramic glazes to promote opacity, as well as in glass compounds to make beautiful, opaque white glazes.
A range of Zirconium silicate materials is available.
However, for special applications, alternative particle sizes can be processed.
Zirconium silicate is used for ceramics, opal glaze, coating enhancers, etc. catalysts for the manufacture of alkanes and alkenes.


Zirconium silicate is an excellent opacifying agent, which is widely used in the production fields of high-grade ceramic glaze, advanced refractory fiber, TV display screen and so on.
Zirconium Silicate is also a special glass, porcelain with raw materials and special rubber reinforced resin filler.
Zirconium Silicate improves erosion and chemical resistance when used in glazes.


In spite of being used widely in the production of various ceramics, it is also widely used in refractory materials, zirconium ramming materials, casting materials spray coatings and dental crowns.
Zirconium silicate is used in ceramics, opalescent glazes, paint enhancers, etc.
Zirconium silicate is used catalysts for the manufacture of alkanes and alkenes.


Zirconium silicate is used silicone rubber stabilizer
Zirconium silicate is used manufacturing metal zirconium and zirconium oxide.
Zirconium silicate is used industrial zirconium raw materials, gemstones, catalysts, cementing agents, glass polishing agents, resistors and electrical insulators, refractories, glazes, whitening in ceramic glazes,


Zirconium Silicate is used silicone rubber stabilizer.
Zirconium Silicate is used manufacture of metallic zirconium and zirconia.
Industrial applications of Zirconium Silicate: zirconium raw materials, gems, catalysts, cements, glass polishes, resistors and electrical insulators, refractory materials, glazes, which play a whitening role in ceramic glazes, and can take expensive tin dioxide, Zirconium dioxide can greatly reduce the cost on the glaze, with an average particle size of 1um-1.2um.


Zirconium silicate is used for ceramics, opalescent glazes, paint enhancers, etc
Zirconium Silicate (ZrSiO4) is a ceramic powder that is used for enamels and ceramic glazes.
Depending on the application, Zirconium silicate sand may be calcined at a high temperature giving a stabilised product.
At one of the most sophisticated plants in Europe, Zirconium silicate is processed and milled to the most stringent grading and particle sizes required.


Zirconium silicate uses and applications include: Glaze opacifier; stabilizes color shades; used in white and colored glazes for sanitary ware, wall tile, glazed brick, structural tile, stoneware, dinnerware, special porcelains, refractory compositions, epoxy formulations, encapsulating resins; source of zirconium oxide, metallic zirconium, hafnium; inert filler; abrasive; enamels; catalyst; silicone rubbers; foundry cores; in cements; coatings for casting molds; polishing materials; stabilizer in silicone rubbers; cosmetic creams.


-Uses in Pottery:
Zirconium silicate is normally used in glazes for opacification (converting a transparent glaze to an opaque).
The silicate form or zirconium does not matte glazes (like pure zirconium oxide, actually, zirconium dioxide, does).
The exact amount needed varies between different glaze types.
10-12% is normal, but up to 20% may be required to opacify some transparent glazes.
When the saturation point is achieved crystallization begins to occur.
Zirconium silicate is most effective at low temperatures.
As a glaze opacifier the white color produced by zirconium silicate is often characterized as 'toilet bowl white'.
If the shade of white is too harsh, Zirconium silicate can be toned by shifting part of the opacification burden to tin or by adding a tiny amount of stain (e.g. blue, brown, grey).
The low expansion or Zirconium silicate will tend to reduce crazing in glazes.


-Applications of Zirconium silicate:
*Preparation of ceramic membrane for micro-filtration applications
*Improving The Efficiency Of Fine Grinding – Developments In Ceramic
*Media Technology
*Ultrathin Zirconium Silicate Films Deposited on Si(100)
*Management of norm with particular refernces to zircon minerals
*The effect of grinding media performance on milling and operational behaviour
*Radioactivity in raw materials and end products in the Italian ceramics industry
*Zirconium and Hafnium
-Zirconium silicate is a material commonly used in ceramics, glazes and glazed ceramics.



STRUCTURE AND BONDING of ZIRCONIUM SILICATE:
Zirconium silicate consists of 8-coordinated Zr4+ centers linked to tetrahedral orthosilicate SiO44- sites.
The oxygen atoms are all triply bridging, each with the environment OZr2Si.
Given Zirconium silicate's highly crosslinked structure, Zirconium silicate is hard, and hence prized as gemstone and abrasive.
Zirconium silicate is a d0 ion.
Consequently Zirconium silicate is colorless and diamagnetic.



PRODUCTION of ZIRCONIUM SILICATE:
Zirconium silicate occurs in nature as mineral zircon.
Concentrated sources of zircon are rare.
Zirconium silicate is mined from sand deposits and separated by gravity.
Some sands contain a few percent of zircon.
Zirconium silicate can also be synthesized by fusion of SiO2 and ZrO2 in an arc furnace, or by reacting a zirconium salt with sodium silicate in an aqueous solution.



PREPARATION of ZIRCONIUM SILICATE:
Zirconium silicate occurs in nature as mineral zircon.
Ore is mined from natural deposits and concentrated by various techniques (See Zirconium, Recovery).
Zirconium silicate is separated from sand by electrostatic and electromagnetic methods.
Also, Zirconium silicate can be made by fusion of SiO2 and ZrO2 in an arc furnace, or by reacting a zirconium salt with sodium silicate in aqueous solution.

After mixing zirconium quartz and Soda Ash in a certain proportion, it is sent to a high temperature furnace for roasting at about 1100 ° C.
After roasting, it is pulverized and then sent to a purification tank, and then the pH value is adjusted to acid with hydrochloric acid, additives are then added to purify titanium, iron and other impurities at 60-80 °c, rinsed with water to remove insoluble salts, and the product is obtained by filtration, drying, and jet grinding.



FEATURES of ZIRCONIUM SILICATE:
Providing superior whiteness and opacity in ceramic glazes while glaze reflection and glossiness are maintained.
Increasing crack resistance, chemical resistance, scratch resistance, tensile strength and compressive strength of the glaze.
Also, Zirconium silicate can make soft pastel color and help to stabilize the color shade.
Zirconium silicate can be used to the bodies.

The highest purity Zircon or Zirconium Silicate can be found in deposits close to the American, Australian and South African coasts.
Zirconium Silicate sand is separated from other minerals by ore dressing techniques during which strict controls are made to ensure the quality of the final product.



SYNTHESIS of ZIRCONIUM SILICATE:
-Non-Thermal Synthesis of Mesoporous Zirconium Silicate and its Characterization
-Crystalline, Microporous Zirconium Silicates with MEL Structure
-Atomic layer deposition of zirconium silicate films using zirconium tetra-tert-butoxide and silicon tetrachloride
-Synthesis of glass-ceramic glazes in the ZnO–Al2O3–SiO2–ZrO2 system
-Atomic layer deposition of zirconium silicate films using zirconium tetrachloride and tetra-n-butyl orthosilicate



CHARACTERISTICS of ZIRCONIUM SILICATE:
-Zirconium silicate as a ceramic glaze additive, within a certain particle size range with particle size reduction whiteness, strength, wear resistance, hydrolysis resistance, corrosion resistance are improved, self-cleaning ability enhanced, reduced dosage.
-Because of its strong hydrolysis resistance, zirconium silicate powder can be used as the carrier of nano functional powder in water environment.
-Zirconium silicate can be used as surface coating agent for functional powders due to its strong oxidation resistance.
For example, the red glaze of Chinese red ceramics is made of nano-zirconium silicate coating agent, red and bright color, do not fade.
-Because of the high strength and good wear resistance of zirconium silicate, nanometer zirconium silicate powder is a high quality abrasive medium and engineering ceramic raw material.



ZIRCONIUM SILICATE BRICKS:
Zirconium silicate bricks, characterized by a ZrO2+HfO2 content of more than 64 % are isostatically pressed, moulded by hand or uniaxially pressed.
Isostatically pressed zirconium bricks are characterized by a homogenous and dense structure (porosity 1-5 vol.%) over the total brick volume.
These bricks are mainly used as glass contact material in borosilicate glass melters and as lining or electrode blocks and bushing blocks for the manufacture of textile glass fibre and glass wool.

Porous Zirconium silicate bricks (porosity 15 - 22 vol.%) are used as a security layer in melter bottoms and as a contact indifferent separating layer in the superstructure of soda lime glass melters.
Special qualities with a low flow rate under pressure are used for the superstructure of furnaces and arches of borosilicate glass melters and low alkali special glass melters.



PHYSICAL and CHEMICAL PROPERTIES of ZIRCONIUM SILICATE:
Chemical formula: O4SiZr
Molar mass: 183.305 g·mol−1
Appearance: Colourless crystals
Density: 4.56 g cm−3
Melting point: 1,540 °C (2,800 °F; 1,810 K) (decomposes)
Heat capacity (C): 98.3 J/mol K
Std enthalpy of formation (ΔfH⦵298): -204
Crystal structure: tetragonal
Molecular Weight: 183.31

Appearance: Off-white powder
Melting Point: 2550 °C
Boiling Point: N/A
Density: 3.9 g/cm3
Solubility in H2O: N/A
Tensile Strength: 290 MPa (Ultimate)
Thermal Conductivity: 3.5 W/m-K
Thermal Expansion: 5.0 µm/m-K
Exact Mass: 181.861289
Monoisotopic Mass: 181.861289

Molecular Weight: 183.31
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 181.861284
Monoisotopic Mass: 181.861284
Topological Polar Surface Area: 92.2 Ų
Heavy Atom Count: 6
Formal Charge: 0

Complexity: 19.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Melting point: 2550 °C
Density: 4,56 g/cm3
refractive index: 1.78-1.99
form: nanopowder
color: Yellow to orange
Specific Gravity: 4.56
Odor: Odorless
Water Solubility: Insoluble in water, acids, alkali and aqua regia.
Hydrolytic Sensitivity: 1: no significant reaction with aqueous systems
Merck: 14,10181

Exposure limits ACGIH: TWA 5 mg/m3; STEL 10 mg/m3
NIOSH: IDLH 25 mg/m3; TWA 5 mg/m3; STEL 10 mg/m3
Stability: Stable.
Appearance Form: powder
Colour: grey
Odour: No data available
Odour Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available

Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: No data available
Vapour density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Auto-ignition temperature: No data available
Decomposition temperature: No data available

Viscosity: No data available
Oxidizing properties: No data available
Other safety information: No data available
Molecular Formula: O4SiZr
Molar Mass: 183.3071
Density: 4,56 g/cm3
Melting Point: 2550 °C
Water Solubility: Insoluble in water, acids, alkali and aqua regia.
Appearance: White to light brown fine powder
Specific Gravity: 4.56
Color: Yellow to orange
Odor: Odorless



FIRST AID MEASURES of ZIRCONIUM SILICATE:
-General advice:
Consult a physician.
-If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
-In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
-In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
-If swallowed:
Rinse mouth with water.
Consult a physician.



ACCIDENTAL RELEASE MEASURES of ZIRCONIUM SILICATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZIRCONIUM SILICATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZIRCONIUM SILICATE:
-Control parameters:
*Exposure controls:
-Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZIRCONIUM SILICATE:
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of ZIRCONIUM SILICATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.



SYNONYMS:
Zirconium(IV) silicate
Zirconium(4+) silicate
Zircon
Zirconium(4+) orthosilicate
Zirconium(IV) orthosilicate
Zirconium silicate
Zircon
Zirconite
Zircon (Zr(SiO4))
Zircosil
Micro-Pax
Zirconium orthosilicate
zirconium(4+);silicat
1344-21-4
14940-68-2
Zirconium(IV) silicate (1:1)
Zirconium(IV) silicate
Silicon zirconium oxide (SiZrO4)
Silicic acid, zirconium(4+) salt
Silicic acid (H4SiO4), zirconium(4+) salt (1:1)
Hyacinth
4SY8H89134
Zircosil 15
Standard SF 200
Ultrox 500W
Excelopax
Zircosil 1
Micro-Pax SP
A-PAX 45M
Zircon 30MY
Micro-Pax 20A
Oscal 1224
A-PAX-SA
Zirconium(IV) orthosilicate
Tam 418
Silicic acid, zirconium(4+) salt (1:1)
UNII-4SY8H89134
Zirconium orthosilicate (ZrSiO4)
Zirconium silicon oxide (ZrSiO4)
MZ 1000B
EINECS 233-252-7
ZIRCON FLOUR 100
Zirconium Silicate Nanopowder
ZIRCONIUM SILICON OXIDE
ZIRCONIUM SILICATE
Zirconium Silicate Nanoparticles
DTXSID60892246
ZIRCONIUM SILICATE
ZIRCONIUM SILICATE
Zirconium silicate, Zirconium(IV) silicate, -325 mesh
AKOS025243327
SILICON ZIRCONIUM OXIDE (ZRSIO4)
FT-0695365
SILICIC ACID, ZIRCONIUM SALT (1:1)
Zirconium(IV) Silicate Nanoparticles / Nanopowder
Q2342917
Silicic acid (H4SiO4) zirconium(4+) salt (1:1)
Zirconium(IV) silicate, nanopowder, ZIRCON
ZrSiO4
acorite
auerbachite
Zirconium orthosilicate
Zircosil
azorite=acorite
Zironium Silicate
Zirconium silicate
Zirconium(Ⅳ)silicate
Zirconium(IV) silicate
Zirconite
Zircon
Silicic acid
zirconium(4+) salt
Hyacinth
Zircosil 15
Excelopax
Zircosil
Micro-Pax
Oscal 1224
Tam 418
Zircon
A-PAX-SA
Excelopax
MZ 1000B
Micro-Pax
Micro-Pax 20A
Micro-Pax SP
Oscal 1224
Silicon zirconium oxide (SiZrO4)
Tam 418
Zircon 30MY
Zirconium orthosilicate (ZrSiO4)
Zirconium silicon oxide (ZrSiO4)
Zircosil
Zircosil 1
Silicic acid, zirconium(4+) salt
Silicic acid (H4SiO4), zirconium(4+) salt (1:1)
Zirconium (IV) silicate
ZIRCON
acorite
auerbachite
Zirconium Silicate
dioxido-oxo-silane
ZIRCONIUM(+4)SILICATE
zirconium(+4) cation
zirconium(4+) orthosilicate
zirconium(2+) oxosilanediolate


Zinc Bromide
SYNONYMS Bromide of Zinc; Zinc dibromide; Hydrobromic Acid Zinc Salt; Bromide Salt of Zinc; CAS NO. 7699-45-8
Zinc cyanide
zinc oxide; Zinc white; Zinc flowers ; C.I. pigment white 4; ZnO; cas no: 1314-13-2
Zinc pyrithione
Zn - pyrion; ZnPT; ZPT; zinc omadine ; ZINC PYRITHIONE; N° CAS : 13463-41-7 - Pyrithione de zinc; Origine(s) : Synthétique; Nom INCI : ZINC PYRITHIONE; Nom chimique : Pyridine-2-thiol-1-oxide, zinc complex (2:1); N° EINECS/ELINCS : 236-671-3; Classification : Règlementé, Conservateur. Ses fonctions (INCI); Antipelliculaire : Aide à lutter contre les pellicules; Anti-séborrhée : Aide à contrôler la production de sébum; Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance; Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétique. Noms français : 2-PYRIDINETHIOL-1-OXIDE, ZINC SALT; BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO)ZINC; Pyrithione de zinc; SEL DE ZINC DE ; L'OXYDE DE MERCAPTO-2 PYRIDINE; ZINC PYRIDINE-2-THIOL-1-OXIDE; ZINC PYRIDINETHIONE; Zinc pyrithione; ZINC, BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO-O,S)-, (T-4)-; ZINC, BIS(1-HYDROXY-2(H)-PYRIDINETHONATO)-; ZINC, BIS(2-PYRIDINYLTHIO)-, N,N'-DIOXIDE; ZINC, BIS(2-PYRIDYLTHIO)-, 1,1'-DIOXIDE. Noms anglais : Zinc pyrithione. Utilisation et sources d'émission: Médicament bactéricide et antiséborrhéique; Pyrithione zincç Translated names: Cinko piritionas (lt); Piirition taż-żingu (Piirition taż-żingu) (mt); Pirition cink (cinkov pirition) (hr); Pirition-cink (Cink-pirition) (hu); Piritiona de cinc (es); Piritiona-zinco (piritiona de zinco) (pt); Piritioncinks (cinka piritions) (lv); Piritionă de zinc (ro); Pirytionian cynku (pl); Pyrithion-Zink (Zink-Pyrithion) (de); Pyrithione zinc (Zinc pyrithione) (no); Pyrithione zincique (pyrithione de zinc) (fr); pyrithionzink (da); Pyrithionzink (zinkpyrithion) (nl); Pyritionisinkki (sinkkipyritioni) (fi); Tsinkpüritioon (et); Zinco piritione (piritione zincica) (it); zink-1-oxo-1λ5-pyridin-2-thiolát (cs); zinkium-pyritión (sk); Zinkpyrition (Pyritionzink) (sv); Άλας πυριθειόνης με ψευδάργυρο (Zinc pyrithione) (el); Цинков пиритион (bg). CAS names: Zinc, bis[1-(hydroxy-.kappa.O)-2(1H)-pyridinethionato-.kappa.S2]-, (T-4)-. IUPAC names; 1-oxidopyridine-6-thiolate, zinc (II) cation; 2-Mercaptopyridine N-Oxide Zinc Salt; Bis [1-hydroxy-2(1H)-pyridinethionato-O,S](T-4)-zinc; bis(1-hydroxy-2(1h)-pyridinethionato)zinc; bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4) zinc; Bis(1-hydroxy-2(1H)-pyridinthionato-O,S) zinc; bis(2-pyridylthio)zinc 1,1'-dioxide; bis[1-hydroxy-2-(1H)-pyridine-thionato]zinc; Kopthione Zn; Mercaptopyridine N-oxide zinc salt, Pyrithione; Mercaptopyridine N-oxidezinc salt; pyrithione zinc`; Zinc 1-oxidopyridin-1-ium-2-thiolate; Zinc 2-pyridinethiol-1-oxide; zinc bis(2-thioxopyridin-1(2H) -olate); zinc bis(2-thioxopyridin-1(2H)-olate); Zinc pyridinethione; Zinc pyrithion; Zinc Pyrithione; zinc(2+) bis(2-sulfanylidene-1,2-dihydropyridin-1-olate); ZINC, BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO)- (6CI,7CI,8CI); zinc;1-oxidopyridin-1-ium-2-thiolate ; (T-4)-bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc;, 13463-41-7 [RN]; 2(1H)-Pyridinethione, 1-hydroxy-, zinc salt (2:1) [ACD/Index Name]; 236-671-3 [EINECS]; bis(1-hydroxy-2(1H)-pyridinethionato)zinc; Bis(2-thioxo-1(2H)-pyridinolate) de zinc [French] [ACD/IUPAC Name]; bis(2-thioxopyridin-1(2H)-olate) de zinc; Evafine P 50; Finecide ZPT; Hokucide ZPT; Niccanon SKT; Omadine Zinc; Tomicide Z 50; Vancide P; Wella Crisan; Zinc bis(2-pyridylthio)-N-oxide; Zinc bis(2-thioxo-1(2H)-pyridinolate) [ACD/IUPAC Name]; Zinc bis(2-thioxopyridin-1(2H)-olate);Zinkbis(2-thioxo-1(2H)-pyridinolat) [German] [ACD/IUPAC Name]; {Bis[1-hydroxy-2(1H)-pyridinethionato]zinc}; 1-Hydroxypyridine-2-thione zinc salt; 2-Mercaptopyridine N-Oxide Zinc Salt; BIS(1-HYDROXY-2(H)-PYRIDINETHIONATO)ZINC; Mercaptopyridine N-oxide zinc salt; MFCD00067336 [MDL number]; Pyrithione; Pyrithione zinc;Vancide ZP; Zinc - pyrion; zinc and 1-oxidopyridine-2-thione; Zinc omadine; Zinc pyrethion; zinc pyridinethione; Zinc pyrithione; Zinc pyrithione; ZINC(2+) BIS(2-SULFANYLIDENEPYRIDIN-1-OLATE); Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4)-; Zinc, bis(2-pyridinylthio)-, N,N'-dioxide; Zinc, bis(2-pyridylthio)-, 1,1'-dioxide; Zinc, bis(2-pyridylthio)-, N,N'-dioxide; zinc;1-oxidopyridine-2-thione; Zn - pyrion; ZnPT; ZPT
Zinc Sulfate Heptahydrate
ZDDP;ZnSO4;neozin;Z-Span;Kreatol;optised;Optraex;orazinc;Zincaps;zinklet CAS No.7733-02-0
Zirconium oxide
Zirconyl chloride octahydrate; Zirconium dichloride oxide octahydrate; Zirconium dichloride oxide hydrate; Zirconiumdichloridoxid (German); Oxidicloruro de circonio (Spanish); Oxydichlorure de zirconium (French) CAS NO: 7699-43-6
Zirconium Oxychloride
GLUCONOLACTONE, N° CAS : 90-80-2 - δ-Gluconolactone. Nom INCI : GLUCONOLACTONE, N° EINECS/ELINCS : 202-016-5, Additif alimentaire : E575. Ses fonctions (INCI) : Agent de chélation : Réagit et forme des complexes avec des ions métalliques qui pourraient affecter la stabilité et / ou l'apparence des produits cosmétiques. Agent d'entretien de la peau : Maintient la peau en bon état
α-TOCOPHEROL (ALPHA-TOCOPHEROL)
DESCRIPTION:
α-Tocopherol (alpha-tocopherol) is a type of vitamin E.
E number of α-Tocopherol is "E307".
Vitamin E exists in eight different forms, four tocopherols and four tocotrienols.


IUPAC name: (2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol
CAS Number: 59-02-9
EC Number: 200-412-2

CHEMICAL AND PHYSICAL PROPERTIES OF Α-TOCOPHEROL:
Chemical formula C29H50O2
Molar mass 430.71 g/mol
Appearance yellow-brown viscous liquid
Density 0.950 g/cm3
Melting point 2.5 to 3.5 °C (36.5 to 38.3 °F; 275.6 to 276.6 K)
Boiling point 200 to 220 °C (392 to 428 °F; 473 to 493 K) at 0.1 mmHg
Solubility in water insoluble
Solubility soluble in alcohol, ether, acetone, oils
biological source: synthetic
Quality Level:200
Assay: ≥95.5%
Form: liquid
technique(s)
HPLC: suitable
Color: faint brown to brown yellow to very dark yellow
density: 0.950 g/mL at 20 °C (lit.)
application(s): cell analysis
storage temp.: 2-8°C
Water Solubility 7.0e-06 g/L
logP 8.84
logP 10.51
logS -7.8
pKa (Strongest Acidic) 10.8
pKa (Strongest Basic) -4.9
Physiological Charge 0
Hydrogen Acceptor Count 2
Hydrogen Donor Count 1
Polar Surface Area 29.46 Ų
Rotatable Bond Count 12
Refractivity 135.37 m³•mol⁻¹
Polarizability 55.29 ų
Number of Rings 2
Bioavailability No
Rule of Five No
Ghose Filter No
Veber's Rule No
MDDR-like Rule No

α-Tocopherol is the active form of vitamin E.
α-Tocopherol functions as an hydroperoxyl radical scavenger and protects the organism from oxidative damage.
α-Tocopherol plays a crucial role in cell signalling and regulating immune responses.

α-Tocopherol deficiency is associated with abetalipoproteinemia, cystic fibrosis and celiac disease.
α-Tocopherol has antiproliferative effects.
α-Tocopherol inhibits arsenite-induced damage of human fibroblasts

All feature a chromane ring, with a hydroxyl group that can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain which allows for penetration into biological membranes.
Compared to the others, α-tocopherol is preferentially absorbed and accumulated in humans.
Vitamin E is found in a variety of tissues, being lipid-soluble, and taken up by the body in a wide variety of ways.

The most prevalent form, α-tocopherol, is involved in molecular, cellular, biochemical processes closely related to overall lipoprotein and lipid homeostasis.
Ongoing research is believed to be "critical for manipulation of vitamin E homeostasis in a variety of oxidative stress-related disease conditions in humans."
One of these disease conditions is the α-tocopherol role in the use by malaria parasites to protect themselves from the highly oxidative environment in erythrocytes.




α-Tocopherol is the form of vitamin E that is preferentially absorbed and accumulated in humans.
The measurement of "vitamin E" activity in international units (IU) was based on fertility enhancement by the prevention of miscarriages in pregnant rats relative to α-tocopherol.

Although the mono-methylated form ddd-γ-tocopherol is the most prevalent form of vitamin E in oils, there is evidence that rats can methylate this form to the preferred α-tocopherol, since several generations of rats retained α-tocopherol tissue levels, even when those generations were fed only γ-tocopherol through their lives.

There are three stereocenters in α-tocopherol, so this is a chiral molecule.
The eight stereoisomers of α-tocopherol differ in the arrangement of groups around these stereocenters.
In the image of RRR-α-tocopherol below, all three stereocenters are in the R form.

However, if the middle of the three stereocenters were changed (so the hydrogen was now pointing down and the methyl group pointing up), this would become the structure of RSR-α-tocopherol.
These stereoisomers also may be named in an alternative older nomenclature, where the stereocenters are either in the d or l form.

RRR stereoisomer of α-tocopherol, bonds around the stereocenters are shown as dashed lines (pointing down) or wedges (pointing up).
1 IU of tocopherol is defined as ⅔ milligrams of RRR-α-tocopherol (formerly named d-α-tocopherol or sometimes ddd-α-tocopherol).
1 IU is also defined as 1 milligram of an equal mix of the eight stereoisomers, which is a racemic mixture called all-rac-α-tocopheryl acetate.

This mix of stereoisomers is often called dl-α-tocopheryl acetate, even though it is more precisely dl,dl,dl-α-tocopheryl acetate).
However, 1 IU of this racemic mixture is not now considered equivalent to 1 IU of natural (RRR) α-tocopherol, and the Institute of Medicine and the USDA now convert IU's of the racemic mixture to milligrams of equivalent RRR using 1 IU racemic mixture = 0.45 "milligrams α-tocopherol".


α-Tocopherol is both lipophilic and non-toxic even at high doses so would be an excellent candidate as a lipophilic carrier for oligonucleotides.
Therefore, as an addition to our cholesteryl product line, we offer simple α-Tocopherol (vitamin E) labelling.
Totally synthetic α-Tocopherol is racemic at its three chiral centers and is used to prepare this product.

α-Tocopherol is a fat-soluble vitamin with several forms, but alpha-tocopherol is the only one used by the human body.
Its main role is to act as an antioxidant, scavenging loose electrons—so-called “free radicals”—that can damage cells.
α-Tocopherol also enhances immune function and prevents clots from forming in heart arteries.

Antioxidant vitamins, including vitamin E, came to public attention in the 1980s when scientists began to understand that free radical damage was involved in the early stages of artery-clogging atherosclerosis, and might also contribute to cancer, vision loss, and a host of other chronic conditions.
α-Tocopherol has the ability to protect cells from free radical damage as well as reduce the production of free radicals in certain situations.
However, conflicting study results have dimmed some of the promise of using high dose α-Tocopherol to prevent chronic diseases.







APPLICATIONS OF Α-TOCOPHEROL:
α-Tocopherol has been used as a standard to determine its concentration by reverse-phase high-performance liquid chromatography.
α-Tocopherol has been used to study its rescue effects on chlorine dioxide (ClO2) cytotoxicity.
α-Tocopherol has been used to assess its protective effects on acetaminophen (APAP)-mediated liver damage.

BIOCHEM/PHYSIOL ACTIONS OF Α-TOCOPHEROL:
Tocopherols (TCP) (vitamin E) are a series (α, β, γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring.
Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage.
α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens.
Various isofroms and analogues of tocopherol have opposing and differentiated regulatory activities in vivo.

FUNCTIONAL ACTIVITY OF ALPHA-TOCOPHEROL:
The function of alpha tocopherol is as a fat-soluble antioxidant, which breaks the chain of oxidation reactions which are propagating down a cell membrane or plasma protein by means of newly produced free radicals.

All cell membranes contain fats, and these are easily oxidized by free radical attack through the process of lipid peroxidation.
This chain is broken by alpha-tocopherol which is a thousand times more susceptible to reaction with the peroxyl radicals than unsaturated fatty acids.


This causes the inactivation of the peroxyl radicals, while alpha-tocopherol itself becomes oxidized and loses its anti-oxidant activity.
Vitamin C can regenerate the activity of alpha-tocopherol after it is oxidized.

This action of alpha-tocopherol is essential to the protection of the lipid bilayer of all cell membranes, as well as enzymes and membrane proteins.
alpha-tocopherol also strengthens cell-mediated immunity in several ways.

However, this form of vitamin E does not seem to have a protective effect on chronic diseases such as cardiovascular disease, cancer or cataracts.
There is some evidence that it slows the progression of age-related macular degeneration and was beneficial in the management of diabetes type 2, as well as non-alcoholic liver disease.

STEREOISOMERS OF Α-TOCOPHEROL:
α-Tocopherol has three stereocenters, so it is a chiral molecule.
The eight stereoisomers of α-tocopherol differ in the configuration of these stereocenters.
RRR-α-tocopherol is the natural one.

The older name of RRR-α-tocopherol is d-α-tocopherol, but this d/l naming should no longer be used, because whether l-α-tocopherol should mean SSS enantiomer or the SRR diastereomer is not clear, from historical reasons.
The SRR may be named 2-epi-α-tocopherol, the diastereomeric mixture of RRR-α-tocopherol and 2-epi-α-tocopherol may be called 2-ambo-α-tocopherol (formerly named dl-α-tocopherol).
The mixture of all eight diastereomers is called all-rac-α-tocopherol.

One IU of tocopherol is defined as 2⁄3 milligram of RRR-α-tocopherol (formerly named d-α-tocopherol).
1 IU is also defined as 0.9 mg of an equal mix of the eight stereoisomers, which is a racemic mixture, all-rac-α-tocopheryl acetate.
This mix of stereoisomers is often called dl-α-tocopheryl acetate.
Starting with May 2016, the IU unit is made obsolete, such that 1 mg of "Vitamin E" is 1 mg of d-alpha-tocopherol or 2 mg of dl-alpha-tocopherol

Alpha tocopherols are chiefly used in the supplement industry where they are taken internally for their antioxidant effects in the body.
Research also shows that these results can be achieved through trans-dermal application so topical use of Alpha-tocopherol is a legitimate method to counter oxidation in the skin and subcutaneous tissues.

There are two commonly available forms of Alpha tocopherol:
d-alpha tocopherol - Natural, typically derived from Soy Bean Oil
dl-alpha tocopherol - Synthetic, petrochemical based

Both forms offer antioxidant activity when taken internally but the efficacy of synthetic Alpha-tocopherol is much lower than its natural counterpart.
This is because the liver only recognises the natural version and synthetic versions are preferentially excreted.

This happens to such an extent that natural Alpha-tocopherol is twice as bioavailable as synthetic when taken internally.
At this stage there is no clear evidence as to how this applies to the topical use of Alpha-tocopherol though it is likely that the natural version will also be more effective as well.

WHY IS α -TOCOPHEROL PRESCRIBED?
α-Tocopherol is used as a dietary supplement when the amount of vitamin E taken in the diet is not enough.
People most at risk for α-Tocopherol deficiency are those with a limited variety of food in their diet and people with Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever), cystic fibrosis (an inborn disease that causes problems with breathing, digestion, and reproduction), or who have gastrointestinal (GI) malabsorption problems (problems absorbing food).
α-tocopherol is also used to treat vitamin E deficiency in those at risk due to certain diseases and conditions.

α-tocopherol is in a class of medications called antioxidants.
α-tocopherol is needed by the body to support the immune system and for blood clotting.
α-tocopherol works as an antioxidant to protect your cells against free radicals.

HOW SHOULD α -TOCOPHEROL BE USED?
α-Tocopherol comes as a capsule, gel capsule, and liquid drops to take by mouth.
α-Tocopherol is usually taken once a day or as directed by your doctor.
α-Tocopherol is available without a prescription, but your doctor may prescribe it to treat certain conditions.

Follow the directions on the package or on your product label or doctor's instructions carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take α-Tocopherol exactly as directed.
Do not take more or less of α-Tocopherol or take α-Tocopherol more often than recommended by your doctor.
α-Tocopherol supplements are available alone and in combination with other vitamins.

OTHER USES FOR α-TOCOPHEROL:
α-Tocopherol is used along with other vitamins and minerals to reduce the risk of age-related macular degeneration (AMD; an ongoing disease of the eye that causes loss of the ability to see straight ahead and may make α-Tocopherol more difficult to read, drive, or perform other daily activities) in certain people.









SAFETY INFORMATION ABOUT α-TOCOPHEROL:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

SYNONYMS OF ALPHA- TOCOPHEROL:

(+)-2R,4'R,8'R-alpha-Tocopherol
(+)-2R,4'R,8'R-α-Tocopherol
(+)-2R,4’R,8’R-α-Tocopherol
(+)-a-Tocopherol
(+)-a-tocopherol
(+)-alpha-Tocopherol
(+)-alpha-tocopherol
(+)-α-Tocopherol
(+)-α-tocopherol
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R)-3,4-dihydro-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R,4'r,8'r)-a-Tocopherol
(2R,4'R,8'R)-a-Tocopherol
(2R,4'R,8'R)-alpha-Tocopherol
(2R,4'R,8'R)-α-Tocopherol
(2R,4'R,8'r)-α-tocopherol
(2R,4’R,8’R)-α-Tocopherol
(all-r)-a-tocopherol
(all-R)-alpha-Tocopherol
(all-R)-α-Tocopherol
(R,R,R)-a-Tocopherol
(r,r,r)-a-tocopherol
(R,R,R)-alpha-Tocopherol
(r,r,r)-alpha-tocopherol
(R,R,R)-α-Tocopherol
(R,R,R)-α-tocopherol
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol, 9C
3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-(2R)-2H-1-benzopyran-6-ol
5,7,8-Trimethyltocol
a-D-Tocopherol
a-Tocopherol
a-tocopherol
Almefrol
alpha-D-Tocopherol
alpha-delta-Tocopherol
Alpha-delta-tocopherol
alpha-Tocopherol
Alpha-tocopherol
alpha-Vitamin E
Antisterility vitamin
Covitol biospider
D-a-Tocopherol
d-alpha-Tocopherol
D-alpha-tocopherol
d-α-Tocopherol
D-α-tocopherol
delta-alpha-Tocopherol
Delta-alpha-tocopherol
Denamone
E307
Emipherol
Ephanyl
Ephynal
Eprolin
Etamican
Evitaminum
Natopherol
Phytogermin
Phytogermine
Profecundin
RRR-alpha-Tocopherol
RRR-alpha-tocopherol
RRR-alpha-Tocopheryl
RRR-alpha-tocopheryl
Syntopherol
Tocopherol
Vitamin e
Vitamin E?
Vitamin ea
Vitamin Ealpha
Vitamin Eα
α-D-Tocopherol
α-Tocopherol
α-tocopherol
α-Vitamin E
α-TOCOPHERYL ACETATE
DESCRIPTION:

α-Tocopheryl acetate (alpha-tocopherol acetate), also known as vitamin E acetate, is a synthetic form of vitamin E.
α-Tocopheryl acetate is the ester of acetic acid and α-tocopherol.
The U.S. Centers for Disease Control and Prevention says that vitamin E acetate is a very strong culprit of concern in the 2019 outbreak of vaping-associated pulmonary injury (VAPI), but there is not yet sufficient evidence to rule out contributions from other chemicals.
Vaporization of this ester produces toxic pyrolysis products.

CAS Number: 58-95-7
IUPAC Name: [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
Molecular Formula: C31H52O3


Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.

Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed.
Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E.
Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.

The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years.

Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare.
Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.

This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more.
At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.



Alpha-tocopheryl acetate (ATA) is a specific form of vitamin E that’s often found in skin care products and dietary supplements.
It’s also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate.

Vitamin E is known for its antioxidant properties.
Antioxidants help to protect your body from damaging compounds called free radicals.
Normally, free radicals form when your body converts food into energy.
However, free radicals can also come from UV light, cigarette smoke, and air pollution.

In nature, vitamin E comes in the form of tocopheryl or tocotrienol.
Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta.
Alpha-tocopheryl (AT) is the most active form of vitamin E in humans.


ATA is more stable than AT, meaning it can better withstand environmental stresses such as heat, air, and light.
This makes it ideal for use in supplements and fortified foods because it has a longer shelf life.




USES OF Α-TOCOPHERYL ACETATE IN COSMETICS
α-Tocopheryl acetate is often used in dermatological products such as skin creams.
α-Tocopheryl acetate is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol.
Claims are made for beneficial antioxidant effects.

α-Tocopheryl acetate is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.
α-Tocopheryl acetate is believed that the acetate is slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
Tocopheryl acetate was first synthesized in 1963 by workers at Hoffmann-La Roche.

Although there is widespread use of tocopheryl acetate as a topical medication, with claims for improved wound healing and reduced scar tissue, reviews have repeatedly concluded that there is insufficient evidence to support these claims.
There are reports of vitamin E-induced allergic contact dermatitis from use of vitamin E derivatives such as tocopheryl linoleate and tocopherol acetate in skin care products. Incidence is low despite widespread use.

MISUSE OF Α-TOCOPHERYL ACETATE:
Ingredient in vape liquids:
On September 5, 2019, the United States Food and Drug Administration (US FDA) announced that 10 out of 18, or 56% of the samples of vape liquids sent in by states, linked to the recent vaping-related lung disease outbreak in the United States, tested positive for vitamin E acetate which had been used as a thickening agent by illicit THC vape cartridge manufacturers.
On November 8, 2019, the Centers for Disease Control and Prevention (CDC) identified vitamin E acetate as a very strong culprit of concern in the vaping-related illnesses, but has not ruled out other chemicals or toxicants as possible causes.

The CDC's findings were based on fluid samples from the lungs of 29 patients with vaping-associated pulmonary injury, which provided direct evidence of vitamin E acetate at the primary site of injury in all the 29 lung fluid samples tested.
Research suggests when vitamin E acetate is inhaled, it may interfere with normal lung functioning.
A 2020 study found that vaporizing vitamin E acetate produced carcinogenic alkenes and benzene, but also exceptionally toxic ketene gas, which may be a contributing factor to the pulmonary injuries.

CHEMISTRY OF Α-TOCOPHERYL ACETATE:
At room temperature, α-tocopheryl acetate is a fat-soluble liquid.
α-Tocopheryl acetate has 3 chiral centers and thus 8 stereoisomers.
α-Tocopheryl acetate is made by esterifying α-tocopherol with acetic acid.

2R,4R,8R-isomer, also known as RRR-α-tocopheryl acetate, is the most common isomer used for various purposes.
This is because α-tocopherol occurs in nature primarily as RRR-α-tocopherol.

α-Tocopherol acetate does not boil at atmospheric pressure and begins to degrade at 240 °C.
α-Tocopheryl acetate can be vacuum distilled: it boils at 184 °C at 0.01 mmHg, at 194 °C (0.025 mmHg) and at 224 °C (0.3 mmHg).
In practice, α-Tocopheryl acetate is not degraded notably by air, visible light or UV-radiation.
α-Tocopheryl acetate has a refractive index of 1.4950–1.4972 at 20 °C.

α-Tocopherol acetate is hydrolyzed to α-tocopherol and acetic acid under suitable conditions or when ingested by people.
SAFETY INFORMATION ABOUT α-TOCOPHERYL ACETATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




CHEMICAL AND PHYSICAL PROPERTIES OF Α-TOCOPHEROL ACETATE:
Chemical formula C31H52O3
Molar mass 472.743 g/mol
Appearance pale yellow, viscous liquid
Melting point –27.5 °C
Boiling point 240 °C decays without boiling
Solubility in water insoluble
Solubility soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol
Molecular Weight 472.7 g/mol
XLogP3-AA 10.8
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 3
Rotatable Bond Count 14
Exact Mass 472.39164552 g/mol
Monoisotopic Mass 472.39164552 g/mol
Topological Polar Surface Area 35.5Ų
Heavy Atom Count 34
Formal Charge 0
Complexity 602
Isotope Atom Count 0
Defined Atom Stereocenter Count 3
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
pH value 7 (50 g/l, H₂O, 20 °C) (slurry)
Bulk density 360 kg/m3
Storage : Store at +2°C to +25°C.
all-rac-α-Tocopheryl acetate content (GC, Ph Eur) 50.0 - 57.5 %
all-rac-α-Tocopheryl acetate content (GC, USP) 49.0 - 57.5 %
Identity (TLC) conforms
Identity (GC) conforms
Optical rotation α 20/D (all-rac-α-Tocopheryl acetate) -0.01 - 0.01 °
Heptane (HS-GC) ≤ 5000 ppm
Methanol (HS-GC) ≤ 3000 ppm
Other residual solvents (ICH Q3C) excluded by production process
Loss on drying (130 °C, vacuum, 4 h) ≤ 5.0 %
Total aerobic microbial count (TAMC) ≤ 100 CFU/g
Total combined yeasts/moulds count (TYMC) ≤ 100 CFU/g
Bile-tolerant gram-negative bacteria (absent in 1 g) passes test
Candida albicans (absent in 1 g) passes test
Escherichia coli (absent in 1 g) passes test
Pseudomonas aeruginosa (absent in 1 g) passes test
Salmonella (absent in 10 g)
passes test
Staphylococcus aureus (absent in 1 g)
passes test
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
corresponds to Ph Eur, BP, USP
Salmonella (absent in 10 g)
passes test
Staphylococcus aureus (absent in 1 g)
passes test
CAS number 7695-91-2
EC number 231-710-0
Grade Ph Eur,BP,USP,FCC
Hill Formula C₃₁H₅₂O₃
Molar Mass 472.76 g/mol
HS Code 2936 28 00
Boiling point 224 °C (0.4 hPa)
Density 0.96 g/cm3 (20 °C)
Flash point 225.5 °C
Ignition temperature 303 °C
Melting Point -27.5 °C
Vapor pressure 0.5 hPa (213.8 °C)
Assay (GC, Ph Eur) 96.5 - 102.0 %
Assay (GC, USP) 96.0 - 102.0 %
Assay (GC, FCC) 960 - 1020 I.U./g
Identity (GC) passes test
Identity (IR-spectrum) passes test
Identity (optical rotation) passes test
Identity (wet chemistry) passes test
Optical rotation α 20/D (100 g/l; anhydrous ethanol) -0.01 - 0.01 °
Pb (Lead) ≤ 2 ppm
Heptane (HS-GC) ≤ 5000 ppm
Methanol (HS-GC) ≤ 3000 ppm
Other residual solvents (ICH Q3C) excluded by manucfacturing process
Related substances (Ph Eur, impurity A) ≤ 0.5 %
Related substances (Ph Eur, impurity B) ≤ 1.5 %
Related substances (Ph Eur , impurity C) ≤ 0.5 %
Related substances (Ph Eur, sum of impurities D and E) ≤ 1.0 %
Related substances (Ph Eur, any other impurity) ≤ 0.25 %
Related substances (Ph Eur, total impurities) ≤ 2.5 %
Acidity
passes test


SYNONYMS OF Α-TOCOPHERYL ACETATE:

3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol
Acetate, Tocopherol
alpha Tocopherol
alpha Tocopherol Acetate
alpha Tocopherol Hemisuccinate
alpha Tocopherol Succinate
alpha Tocopheryl Calcium Succinate
alpha-Tocopherol
alpha-tocopherol acetate
alpha-tocopherol hemisuccinate
alpha-tocopherol succinate
alpha-Tocopheryl Calcium Succinate
d alpha Tocopherol
d alpha Tocopheryl Acetate
d-alpha Tocopherol
d-alpha-Tocopheryl Acetate
R,R,R-alpha-Tocopherol
Tocopherol Acetate
Tocopherol Succinate
Tocopherol, d-alpha
Tocopheryl Acetate
vitamin E succinate
Vitamin E acetate
alpha-Tocopherol acetate
58-95-7
Tocopherol acetate
Alfacol
Tocopheryl acetate
D-alpha-tocopherol acetate
D-ALPHA-TOCOPHERYL ACETATE
Ecofrol
Contopheron
Tofaxin
Econ
Ephynal acetate
Tokoferol acetate
Evipherol
Fertilvit
Tocopherex
Tocophrin
Erevit
Gevex
(+)-alpha-Tocopherol acetate
Combinal E
Epsilan-M
E-Toplex
E-Ferol
Endo E Dompe
Ephynal
Spondyvit
Juvela
alpha-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Vitamin Ealpha acetate
Vitamin E acetate, d-
Nanotopes
Simmyungsaengmosu
NatAc
Tinoderm E
Natur-E granulate
DL-alpha-Tocopheryl acetate
Lutavit E 50
(+)-alpha-Tocopheryl acetate
CCRIS 4389
(R,R,R)-alpha-Tocopheryl acetate
C31H52O3
EINECS 200-405-4
UNII-A7E6112E4N
(+-)-alpha-Tocopherol acetate
52225-20-4
D-alpha tocoferil acetate
alpha-Tocopherol acetate, all rac
(2R,4'R,8'R)-alpha-Tocopheryl acetate
A7E6112E4N
DL-alpha-Tocopherylacetate
d-Alpha Tocopheryl Acetate
.alpha.-Tocopherol acetate
alpha-Tocopherol acetate, (2R,4'R,8'R)-
EINECS 231-710-0
MFCD00072052
RRR-alpha-tocopheryl acetate
(+)-alfa-tocopherol acetate
alpha-tocopheryl acetate, D-
D-.alpha.-Tocopherol acetate
Tocopheryl acetate, D-alpha-
Vitamin E Acetate (D-form)
UNII-9E8X80D2L0
Vectan (TN)
BRN 0097512
CCRIS 6054
54-22-8
DTXSID1031096
CHEBI:32321
9E8X80D2L0
D-|A-Tocopherol acetate
Tocopherolacetate, alpha-
DL-alpha tocopheryl acetate
EINECS 257-757-7
MFCD00072042
T-3376
d-Vitamin E acetate
Tocopherol acetate [JAN]
.alpha.-Tocopheryl acetate
Tocopherol acetate (JP17)
Tocopheryl Acetate, d-Alpha
CHEMBL1047
NCGC00166253-02
SCHEMBL22298
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
MLS001335985
MLS001335986
DTXCID601356
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-
DTXSID3021356
(+)-.alpha.-Tocopherol acetate
(+)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherylacetate (Vitamin E acetate)
EC 231-710-0
Syntopherol acetate
HMS2230C20
5-17-04-00169 (Beilstein Handbook Reference)
Tox21_111491
Tox21_111564
Tox21_113467
Tox21_303444
ALPHA-TOCOPHEROL ACETATE, D-
ALPHA-TOCOPHEROL ACETATE. D-
LS-245
Rovimix E 50SD
(R,R,R)-.alpha.-Tocopheryl acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
AKOS025117621
NSC 755840
NSC-755840
Tox21_113467_1
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
1406-70-8
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-
.ALPHA.-TOCOPHEROL ACETATE, D-
CAS-58-95-7
NCGC00095255-08
NCGC00166253-01
NCGC00257504-01
DL--Tocopherol acetate
AS-13784
J24.807J
LS-39402
LS-53371
SMR000857327
CAS-52225-20-4
O-Acetyl-alpha-tocopherol
(2R,4'R,8'R)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherol acetate, >=96% (HPLC)
Vitamin E acetate dl-form
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
C13202
D01735
DL-alpha-Tocopherol acetate, analytical standard
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-b- enzopyran-6-ol, acetate
d,l-alpha-Tocopheryl acetate
Eusovit
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-rel-
D-.alpha.-Tocopheryl acetate
Alpha-tocopherol acetate, dl-
Q-201933
vitamin E acetate, (2R-(2R*(4R*,8R*)))-isomer
W-109259
ECA8C22F-B5D3-4B88-A9B7-AF6C600001BB
vitamin E acetate, ((2R*(4R*,8R*))-(+-))-isomer
DL-alpha-Tocopherol acetate, tested according to Ph.Eur.
DTXCID60196594
OptoVit E
SynAC
Rovimix E 50
Alpha Tocopheryl Acetate, United States Pharmacopeia (USP) Reference Standard
alpha-Tocopherol acetate, European Pharmacopoeia (EP) Reference Standard
DL-alpha-Tocopherol acetate, certified reference material, TraceCERT(R)
DL-alpha-Tocopherylacetate (Vitamin E acetate) 10 microg/mL in Acetonitrile
(+)-alpha-Tocopherol acetate, BioReagent, suitable for insect cell culture, ~1360 IU/g
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #
Tocopheryl Acetate, a, Pharmaceutical Secondary Standard; Certified Reference Material
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate
(2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate
2H-1-benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2R*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,(2R*(4R*,8R*))-(+-)-
All-rac-alpha-tocopheryl acetate for peak identification, European Pharmacopoeia (EP) Reference Standard
Tocopheryl acetate,alpha
Alpha Tocopheryl Acetate
D-ALPHA TOCOFERIL ACETATE (MART.)
D-ALPHA TOCOFERIL ACETATE [MART.]
UNII-WR1WPI7EW8
Copherol 12250
d-|ATocopheryl Acetate
O-Acetyl-|A-tocopherol
alpha-Tocopherylis acetas
AC1L3BMH
DL-|A-Tocopheryl acetate
.alpha.-tocopherol acetate, dl-
AC1Q1PB2
(+)-|A-Tocopherol acetate
(+)-|A-Tocopheryl Acetate
all-rac-|A-Tocopheryl acetate
DL-ALPHA-TOCOPHEROLACETATE
C31-H52-O3
(R,R,R)-|A-Tocopheryl Acetate
(2R,4'R,8'R)-alpha-Tocopherol acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-rel-
Tocopherol, acetate
Acetate, Tocopherol
ZINC4172337
alpha-tocopherylacetat
FT-0624407
a- tocopheryl acetate
D--Tocopherol acetate
(2R,4'R,8'R)-|A-Tocopherol Acetate
(2R,4'R,8'R)-|A-Tocopheryl Acetate
SC-16401
SC-18242
alpha Tocopherol Acetate
DSSTox_CID_1356
d alpha Tocopheryl Acetate
DL-alpha-Tocopherol acetate, 50% powder form
J10308
DL-alpha-Tocopherol acetate, EP/USP/FCC grade
DSSTox_RID_76104
DSSTox_RID_78863
DSSTox_GSID_21356
DSSTox_GSID_31096
Vitamin E acetate (unlabeled)
VITAMIN E ALPHA ACETATE
(+)- alpha -Tocopherol acetate
TOCOPHERYL ACETATE,D-ALPHA
D-alpha-Tocopheryl acetate, 97%
MolPort-003-928-528
DL-alpha-Tocopheryl acetate, 98%
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate
3, 4- dihydro- 2, 5, 7, 8- tetramethyl- 2- (4, 8, 12- trimethyltridecyl)- 2H- benzopyran- 6- yl acetate
HY-B1278
TOCOPHERYL ACETATE [WHO-DD]
Vitamin E acetate, unspecified form
TOCOPHERYL ACETATE, alpha, D-
s3681
Vitamin E (alpha tocopherol acetate)
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate
CCG-269474
CS-O-00415
DB14002
.ALPHA.-TOCOPHEROL ACETATE. D-
(+-)-alpha-Tocopherol Acetateacid ester
.ALPHA.-TOCOPHEROL ACETATE [MI]
TOCOPHERYL ACETATE, .ALPHA., D-
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate
[2R*(4R*,8R*)]-()-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
133-80-2
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,6-acetate, (2R)-
AK176402
all-rac-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
ALPHA TOCOPHERYL ACETATE (USP-RS)
RRR-ALPHA-TOCOPHERYL ACETATE [FCC]
TOCOPHERYL ACETATE,D-ALPHA [VANDF]
CS-0013056
T2322
VITAMIN E (ALPHA-TOCOPHERYL ACETATE)
A11606
D70796
alpha-TOCOPHEROL ACETATE, UNSPECIFIED FORM
EN300-7398027
A865381
Q364160
Z2681891483
UNII-WR1WPI7EW8 component ZAKOWWREFLAJOT-CEFNRUSXSA-N
Vitamin E acetate (dimethyl-13C2, acetyl-13C2, 99%; dimethyl-D6, 98%)
(+)-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE
(2R-(2R*(4R*,8R*)))-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRI-DECYL)-2H-1-BENZOPYRAN-6-OL ACETATE
[2R*(4R*,8R*)]-(+-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
12741-00-3
1407-18-7
26243-95-8
2H-1-Benzopiran-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R,8R)-4,8,12-trimetiltridecil]-, 6-acetato, (2R)-rel-
2H-1-benzopirano-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R, 8R)-4,8,12-trimetiltridecil]-, 6-acetato, ( 2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-(.+.)-
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate, (2R)-





α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE)
α-Tocopheryl acetate (alpha-tocopherol acetate) is a specific form of vitamin E that’s often found in skin care products and dietary supplements.
α-Tocopheryl acetate (alpha-tocopherol acetate) is a natural form of vitamin E and it is stable in terms of shelf life.


CAS Number: 58-95-7 RRR-α-isomer
EC Number: 200-405-4
MDL Number: MFCD00072052
Chemical formula: C31H52O3


α-Tocopheryl acetate (alpha-tocopherol acetate) is a natural form of vitamin E and it is stable in terms of shelf life.
α-Tocopheryl acetate (alpha-tocopherol acetate) is probably the best form for people actively trying to prevent heart disease.
α-Tocopheryl acetate (alpha-tocopherol acetate) is used in the dietary and clinical supplementations.


α-Tocopheryl acetate (alpha-tocopherol acetate) is a off-white crystalline solid
α-Tocopheryl acetate (alpha-tocopherol acetate) is the most bioactive of the naturally occurring forms of Vitamin E.
Richest sources are green vegetables, grains, and oils, particularly palm, safflower and sunflower oils.


α-Tocopheryl acetate (alpha-tocopherol acetate) is a tocol.
α-Tocopheryl acetate (alpha-tocopherol acetate) is odorless off-white crystals.
α-Tocopheryl acetate (alpha-tocopherol acetate) darkens at 401° F.


α-Tocopheryl acetate (alpha-tocopherol acetate), also known as vitamin E acetate, is a synthetic form of vitamin E.
α-Tocopheryl acetate (alpha-tocopherol acetate) is an ester of acetic acid and α-tocopherol.
α-Tocopheryl acetate (alpha-tocopherol acetate) has many proposed uses, primarily because of its antioxidant properties, which are thought to protect cells from free radicals.


α-Tocopheryl acetate (alpha-tocopherol acetate), also known as vitamin E acetate, is a common vitamin supplement with the molecular formula C31H52O3 (for 'α' form).
α-Tocopheryl acetate (alpha-tocopherol acetate) is the ester of acetic acid and tocopherol (vitamin E).


While there are many studies on the potential benefits of AT, studies on the benefits of α-Tocopheryl acetate (alpha-tocopherol acetate) are limited.
The results of these studies on α-Tocopheryl acetate (alpha-tocopherol acetate) are mixed.
α-Tocopheryl acetate (alpha-tocopherol acetate) usually needs to be used with other vitamins and minerals to have a beneficial effect.


α-Tocopheryl acetate (alpha-tocopherol acetate) belongs to the class of organic compounds known as vitamin e compounds.
These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.
α-Tocopheryl acetate (alpha-tocopherol acetate), also known as a-tocopherol acetic acid, belongs to the class of organic compounds known as vitamin E compounds.


These are a group of fat-soluble compounds containing or derived either from a tocopherol or a tocotrienol skeleton.
α-Tocopheryl acetate (alpha-tocopherol acetate) is based on a literature review a significant number of articles have been published on alpha-Tocopherol acetate.


α-Tocopheryl acetate (alpha-tocopherol acetate), also known simply as tocopheryl acetate, is a synthetic form of vitamin E found in dietary supplements and skin care products.
α-Tocopheryl acetate (alpha-tocopherol acetate) appears as odorless off-white crystals.


α-Tocopheryl acetate (alpha-tocopherol acetate) darkens at 401 °F.
α-Tocopheryl acetate (alpha-tocopherol acetate) acetate is a tocol.
α-Tocopheryl acetate (alpha-tocopherol acetate) is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.


In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.
Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of α-Tocopheryl acetate (alpha-tocopherol acetate) that is most commonly used as a food additive when needed.


Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in α-Tocopheryl acetate (alpha-tocopherol acetate).
Most individuals obtain adequate α-Tocopheryl acetate (alpha-tocopherol acetate) intake from their diets; genuine vitamin E deficiency is considered to be rare.


Nevertheless, α-Tocopheryl acetate (alpha-tocopherol acetate) is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.
This biologic action of α-Tocopheryl acetate (alpha-tocopherol acetate) consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more.


At the moment however, there exists a lack of formal data and evidence to support any such additional indications for α-Tocopheryl acetate (alpha-tocopherol acetate) use.
α-Tocopheryl acetate (alpha-tocopherol acetate) is a natural product found in Senegalia catechu, Myriactis humilis, and Senegalia polyacantha with data available.


α-Tocopheryl acetate (alpha-tocopherol acetate) is a natural tocopherol and one of the most potent antioxidant tocopherols.
α-Tocopheryl acetate (alpha-tocopherol acetate) exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus.
α-Tocopheryl acetate (alpha-tocopherol acetate) has four methyl groups on the 6-chromanol nucleus.


The natural d form of α-Tocopheryl acetate (alpha-tocopherol acetate) is more active than its synthetic dl-alpha-tocopherol racemic mixture.
α-Tocopheryl acetate (alpha-tocopherol acetate) is a specific form of vitamin E that’s often found in skin care products and dietary supplements.
α-Tocopheryl acetate (alpha-tocopherol acetate)’s also known as tocopheryl acetate, tocopherol acetate, or vitamin E acetate.


α-Tocopheryl acetate (alpha-tocopherol acetate) is known for its antioxidant properties.
Antioxidants help to protect your body from damaging compounds called free radicals.
Normally, free radicals form when your body converts food into energy.


However, free radicals can also come from UV light, cigarette smoke, and air pollution.
In nature, α-Tocopheryl acetate (alpha-tocopherol acetate) comes in the form of tocopheryl or tocotrienol.
Both tocopheryl and tocotrienol have four forms, known as alpha, beta, gamma, and delta.


α-Tocopheryl acetate (alpha-tocopherol acetate) is the most active form of vitamin E in humans.
α-Tocopheryl acetate (alpha-tocopherol acetate) is more stable than AT, meaning it can better withstand environmental stresses such as heat, air, and light.
This makes α-Tocopheryl acetate (alpha-tocopherol acetate) ideal for use in supplements and fortified foods because it has a longer shelf life.


Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements.
In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers.


α-Tocopheryl acetate (alpha-tocopherol acetate), also known as vitamin E acetate, is a synthetic form of vitamin E.
α-Tocopheryl acetate (alpha-tocopherol acetate) is the ester of acetic acid and α-tocopherol.



USES and APPLICATIONS of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
α-Tocopheryl acetate (alpha-tocopherol acetate) is used in prevention and treatment of vitamin E deficiencies.
α-Tocopheryl acetate (alpha-tocopherol acetate) is used as a component of growth medium for retinal cell lines.
α-Tocopheryl acetate (alpha-tocopherol acetate) is used as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables.


α-Tocopheryl acetate (alpha-tocopherol acetate) is used in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano).
α-Tocopheryl acetate (alpha-tocopherol acetate) is often used in dermatological products such as skin creams.
α-Tocopheryl acetate (alpha-tocopherol acetate) is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol.


Claims are made for beneficial antioxidant effects.
α-Tocopheryl acetate (alpha-tocopherol acetate) is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.


α-Tocopheryl acetate (alpha-tocopherol acetate) is believed that the acetate slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
Although there is widespread use of α-Tocopheryl acetate (alpha-tocopherol acetate) as a topical medication, with claims for improved wound healing and reduced scar tissue, reviews have repeatedly concluded that there is insufficient evidence to support these claims.


There are reports of vitamin E-induced allergic contact dermatitis from the use of vitamin-E derivatives such as tocopheryl linoleate and α-Tocopheryl acetate (alpha-tocopherol acetate) in skin care products.
Incidence is low despite widespread use.


Cosmetic Uses of α-Tocopheryl acetate (alpha-tocopherol acetate): antioxidants and skin conditioning.
α-Tocopheryl acetate (alpha-tocopherol acetate) is considered the most stable and active form of vitamin E and the best option overall for treating vitamin E deficiency.


α-Tocopheryl acetate (alpha-tocopherol acetate) is marketed to prevent several health conditions or diseases.
α-Tocopheryl acetate (alpha-tocopherol acetate) itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement.


Moreover, α-Tocopheryl acetate (alpha-tocopherol acetate) is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed 6.
α-Tocopheryl acetate (alpha-tocopherol acetate) is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E.


This biologic action of α-Tocopheryl acetate (alpha-tocopherol acetate) consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more.


At the moment however, there exists a lack of formal data and evidence to support any such additional indications for α-Tocopheryl acetate (alpha-tocopherol acetate) use.
α-Tocopheryl acetate (alpha-tocopherol acetate), known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects.


Nevertheless, α-Tocopheryl acetate (alpha-tocopherol acetate) is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.
α-Tocopheryl acetate (alpha-tocopherol acetate) may be of limited benefit in some with asthma and rheumatoid arthritis.


α-Tocopheryl acetate (alpha-tocopherol acetate) may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome.
α-Tocopheryl acetate (alpha-tocopherol acetate) may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported.


α-Tocopheryl acetate (alpha-tocopherol acetate) may help relieve some muscle cramps.
α-Tocopheryl acetate (alpha-tocopherol acetate) is often used in dermatological products such as skin creams.
α-Tocopheryl acetate (alpha-tocopherol acetate) is not oxidized and can penetrate through the skin to the living cells, where about 5% is converted to free tocopherol.


Claims are made for beneficial antioxidant effects.
α-Tocopheryl acetate (alpha-tocopherol acetate) is used as an alternative to tocopherol itself because the phenolic hydroxyl group is blocked, providing a less acidic product with a longer shelf life.


It is believed that α-Tocopheryl acetate (alpha-tocopherol acetate) is slowly hydrolyzed after it is absorbed into the skin, regenerating tocopherol and providing protection against the sun's ultraviolet rays.
α-Tocopheryl acetate (alpha-tocopherol acetate) was first synthesized in 1963 by workers at Hoffmann-La Roche.


Although there is widespread use of α-Tocopheryl acetate (alpha-tocopherol acetate) as a topical medication, with claims for improved wound healing and reduced scar tissue, reviews have repeatedly concluded that there is insufficient evidence to support these claims.


There are reports of vitamin E-induced allergic contact dermatitis from use of α-Tocopheryl acetate (alpha-tocopherol acetate) derivatives such as tocopheryl linoleate and tocopherol acetate in skin care products.
Incidence of α-Tocopheryl acetate (alpha-tocopherol acetate) is low despite widespread use.



USE OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE) IN COSMETICS
α-Tocopheryl acetate (alpha-tocopherol acetate) is commonly used in dermatological products such as skin creams.
α-Tocopheryl acetate (alpha-tocopherol acetate) is not oxidized and penetrates through the skin into living cells where about 5% is converted to free tocopherol.
Beneficial antioxidant effects are claimed.
α-Tocopheryl acetate (alpha-tocopherol acetate) is used as an alternative to tocopherol itself as the phenolic hydroxyl group is blocked resulting in a product with lower acidity and longer shelf life.
Acetate hydrolyzes slowly after being absorbed into the skin, and is thought to regenerate tocopherols and protect them from the sun's UV rays.
α-Tocopheryl acetate (alpha-tocopherol acetate) was first synthesized in 1963 by an employee of Hoffmann-La Roche.
α-Tocopheryl acetate (alpha-tocopherol acetate) is widely used as a topical agent, claiming improved wound healing and reduced scar tissue, but reviews have repeatedly concluded that there is insufficient evidence to support this.
Vitamin E-induced allergic contact dermatitis has been reported when vitamin E derivatives such as tocopheryl linoleate and α-Tocopheryl acetate (alpha-tocopherol acetate) are used in skin care products.
Despite α-Tocopheryl acetate (alpha-tocopherol acetate)'s widespread use, its incidence is low.



PHARMACODYNAMICS, α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
α-Tocopheryl acetate (alpha-tocopherol acetate) has antioxidant activity.
α-Tocopheryl acetate (alpha-tocopherol acetate) may also have anti-atherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane-stabilizing and antiproliferative actions.

α-Tocopheryl acetate (alpha-tocopherol acetate) is a collective term used to describe eight separate forms, the best-known form being alpha-tocopherol.
α-Tocopheryl acetate (alpha-tocopherol acetate) is a fat-soluble vitamin and is an important antioxidant.
α-Tocopheryl acetate (alpha-tocopherol acetate) acts to protect cells against the effects of free radicals, which are potentially damaging by-products of the body's metabolism.

α-Tocopheryl acetate (alpha-tocopherol acetate) is often used in skin creams and lotions because it is believed to play a role in encouraging skin healing and reducing scarring after injuries such as burns.
There are three specific situations when a α-Tocopheryl acetate (alpha-tocopherol acetate) deficiency is likely to occur.

α-Tocopheryl acetate (alpha-tocopherol acetate) is seen in persons who cannot absorb dietary fat, has been found in premature, very low birth weight infants (birth weights less than 1500 grams, or 3½ pounds), and is seen in individuals with rare disorders of fat metabolism.
α-Tocopheryl acetate (alpha-tocopherol acetate) deficiency is usually characterized by neurological problems due to poor nerve conduction.

Symptoms may include infertility, neuromuscular impairment, menstrual problems, miscarriage and uterine degradation.
Preliminary research has led to a widely held belief that α-Tocopheryl acetate (alpha-tocopherol acetate) may help prevent or delay coronary heart disease.
Antioxidants such as α-Tocopheryl acetate (alpha-tocopherol acetate) help protect against the damaging effects of free radicals, which may contribute to the development of chronic diseases such as cancer.

α-Tocopheryl acetate (alpha-tocopherol acetate) also protects other fat-soluble vitamins (A and B group vitamins) from destruction by oxygen.
Low levels of α-Tocopheryl acetate (alpha-tocopherol acetate) have been linked to increased incidence of breast and colon cancer.



CHEMISTRY OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
α-Tocopheryl acetate (alpha-tocopherol acetate) is a fat-soluble liquid at room temperature.
α-Tocopheryl acetate (alpha-tocopherol acetate) has 3 chiral centers and thus 8 stereoisomers.
α-Tocopheryl acetate (alpha-tocopherol acetate) is made by esterifying α-tocopherol with acetic acid.

α-Tocopheryl acetate (alpha-tocopherol acetate) is the most common isomer used for various purposes.
This is because α-tocopherol exists primarily as RRR-α-tocopherol in nature.
Alpha-tocopheryl acetate does not boil at atmospheric pressure and begins to decompose at 240°C.

Vacuum distillation of α-Tocopheryl acetate (alpha-tocopherol acetate) is possible.
Boiling of α-Tocopheryl acetate (alpha-tocopherol acetate) is at 184 °C, 0.01 mmHg, 194 °C (0.025 mmHg), and 224 °C (0.3 mmHg).
In fact, α-Tocopheryl acetate (alpha-tocopherol acetate) is not particularly degraded by air, visible light, or ultraviolet light.

The refractive index of α-Tocopheryl acetate (alpha-tocopherol acetate) at 20 °C is between 1.4950 and 1.4972.
α-Tocopheryl acetate (alpha-tocopherol acetate) is hydrolyzed to alpha-tocopherol and acetic acid under appropriate conditions or when ingested by humans.
α-Tocopheryl acetate (alpha-tocopherol acetate) exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus.

α-Tocopheryl acetate (alpha-tocopherol acetate) has four methyl groups on the 6-chromanol nucleus.
The natural d form of α-Tocopheryl acetate (alpha-tocopherol acetate)l is more active than its synthetic dl-alpha-tocopherol racemic mixture.



ALTERNATIVE PARENTS OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
*Diterpenoids
*1-benzopyrans
*Alkyl aryl ethers
*Benzenoids
*Carboxylic acid esters
*Oxacyclic compounds
*Monocarboxylic acids and derivatives
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
*Diterpenoid
*Chromane
*Benzopyran
*1-benzopyran
*Alkyl aryl ether
*Benzenoid
*Carboxylic acid ester
*Carboxylic acid derivative
*Oxacycle
*Organoheterocyclic compound
*Ether
*Monocarboxylic acid or derivatives
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Carbonyl group
*Organooxygen compound
*Aromatic heteropolycyclic compound



AIR AND WATER REACTIONS OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
α-Tocopheryl acetate (alpha-tocopherol acetate) may be sensitive to prolonged exposure to light and air.
α-Tocopheryl acetate (alpha-tocopherol acetate) is insoluble in water.



REACTIVITY PROFILE OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
α-Tocopheryl acetate (alpha-tocopherol acetate) is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.



POTENTIAL BENEFITS OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
Using AT on the skin, especially with vitamin C, helps to prevent UV damage to the skin.
In a review of studies, the Linus Pauling Institute at Oregon State University found that using AT with vitamin C on the skin decreased sunburned cells, DNA damage, and skin pigmentation following UV exposure.

However, AT is less stable in the environment than α-Tocopheryl acetate (alpha-tocopherol acetate), which makes it harder to store.
While α-Tocopheryl acetate (alpha-tocopherol acetate) is less sensitive to heat and light than AT is, there’s less conversion of α-Tocopheryl acetate (alpha-tocopherol acetate) to the active AT form within the skin.

This is because the cells in the upper layer of your skin are much less metabolically active.
As a result, using cosmetic products containing α-Tocopheryl acetate (alpha-tocopherol acetate) on your skin may not be very effective.
This is supported by a study from 2011 published in the Medical Principles and Practice journal.

Using several commercial skin care products, researchers looked at the conversion of α-Tocopheryl acetate (alpha-tocopherol acetate) to the active AT form in the skin of live rats.
They found that, while there was α-Tocopheryl acetate (alpha-tocopherol acetate) in the upper levels of the skin after using the product, there was no active AT.



CHEMISTRY OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
At room temperature, α-Tocopheryl acetate (alpha-tocopherol acetate) is a fat-soluble liquid.
α-Tocopheryl acetate (alpha-tocopherol acetate) has 3 chiral centers and thus 8 stereoisomers.
α-Tocopheryl acetate (alpha-tocopherol acetate) is made by esterifying α-tocopherol with acetic acid.

2R,4R,8R-isomer, also known as α-Tocopheryl acetate (alpha-tocopherol acetate), is the most common isomer used for various purposes.
This is because α-Tocopheryl acetate (alpha-tocopherol acetate) occurs in nature primarily as RRR-α-tocopherol.
α-Tocopherol acetate does not boil at atmospheric pressure and begins to degrade at 240 °C.

α-Tocopheryl acetate (alpha-tocopherol acetate) can be vacuum distilled: it boils at 184 °C at 0.01 mmHg, at 194 °C (0.025 mmHg) and at 224 °C (0.3 mmHg).
In practice, α-Tocopheryl acetate (alpha-tocopherol acetate) is not degraded notably by air, visible light or UV-radiation.
α-Tocopheryl acetate (alpha-tocopherol acetate) has a refractive index of 1.4950–1.4972 at 20 °C.
α-Tocopheryl acetate (alpha-tocopherol acetate) is hydrolyzed to α-tocopherol and acetic acid under suitable conditions or when ingested by people.



WHERE CAN I FIND α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE)?
Cosmetics and supplements:
You’ll find α-Tocopheryl acetate (alpha-tocopherol acetate) in a variety of skin care products.
The antioxidant properties of α-Tocopheryl acetate (alpha-tocopherol acetate) can help to prevent damage to skin caused by free radicals from UV exposure.
α-Tocopheryl acetate (alpha-tocopherol acetate) may also have an anti-inflammatory effect on the skin.

Due to its higher stability, α-Tocopheryl acetate (alpha-tocopherol acetate) is also used in vitamin E dietary supplements.
When taken orally, α-Tocopheryl acetate (alpha-tocopherol acetate) is converted to AT within the intestine.
α-Tocopheryl acetate (alpha-tocopherol acetate) is in most multi-vitamins, so be sure to check how much is in your multi-vitamin if you take one, before adding a supplement.



FOODS, α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
In addition to dietary supplements and cosmetic products, you can find vitamin E in the following foods:
*green leafy vegetables, such as broccoli and spinach
*oils, such as sunflower oil, wheat germ oil, and corn oil
*sunflower seeds
*nuts, such as almonds and peanuts
*whole grains
*fruits, such as kiwi and mango

α-Tocopheryl acetate (alpha-tocopherol acetate) is also added to fortified foods, such as cereals, fruit juices, and many spreads.
You can check food labels to see if α-Tocopheryl acetate (alpha-tocopherol acetate) has been added.
If you want to increase your α-Tocopheryl acetate (alpha-tocopherol acetate) intake, you should start by first increasing your intake of these foods.




MECHANISM OF ACTION OF α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
Although all forms of α-Tocopheryl acetate (alpha-tocopherol acetate) exhibit antioxidant activity, it is known that the antioxidant activity of vitamin E is not sufficient to explain the vitamin's biological activity.

α-Tocopheryl acetate (alpha-tocopherol acetate)'s anti-atherogenic activity involves the inhibition of the oxidation of LDL and the accumulation of oxLDL in the arterial wall.
α-Tocopheryl acetate (alpha-tocopherol acetate) also appears to reduce oxLDL-induced apoptosis in human endothelial cells.

Oxidation of LDL is a key early step in atherogenesis as it triggers a number of events which lead to the formation of atherosclerotic plaque.
In addition, α-Tocopheryl acetate (alpha-tocopherol acetate) inhibits protein kinase C (PKC) activity.

PKC plays a role in smooth muscle cell proliferation, and, thus, the inhibition of PKC results in inhibition of smooth muscle cell proliferation, which is involved in atherogenesis.

α-Tocopheryl acetate (alpha-tocopherol acetate)'s antithrombotic and anticoagulant activities involves the downregulation of the expression of intracellular cell adhesion molecule(ICAM)-1 and vascular cell adhesion molecule(VCAM)-1 which lowers the adhesion of blood components to the endothelium.

In addition, α-Tocopheryl acetate (alpha-tocopherol acetate) upregulates the expression of cytosolic phospholipase A2 and cyclooxygenase (COX)-1 which in turn enhances the release of prostacyclin.
Prostacyclin is a vasodilating factor and inhibitor of platelet aggregation and platelet release.

α-Tocopheryl acetate (alpha-tocopherol acetate) is also known that platelet aggregation is mediated by a mechanism involving the binding of fibrinogen to the glycoprotein IIb/IIIa (GPIIb/IIIa) complex of platelets.

GPIIb/IIIa is the major membrane receptor protein that is key to the role of the platelet aggregation response.
GPIIb is the alpha-subunit of this platelet membrane protein.

Alpha-tocopherol downregulates GPIIb promoter activity which results in reduction of GPIIb protein expression and decreased platelet aggregation.
α-Tocopheryl acetate (alpha-tocopherol acetate) has also been found in culture to decrease plasma production of thrombin, a protein which binds to platelets and induces aggregation.

A metabolite of α-Tocopheryl acetate (alpha-tocopherol acetate) called vitamin E quinone or alpha-tocopheryl quinone (TQ) is a potent anticoagulant.
This metabolite inhibits vitamin K-dependent carboxylase, which is a major enzyme in the coagulation cascade.

The neuroprotective effects of α-Tocopheryl acetate (alpha-tocopherol acetate) are explained by its antioxidant effects.
Many disorders of the nervous system are caused by oxidative stress.
α-Tocopheryl acetate (alpha-tocopherol acetate) protects against this stress, thereby protecting the nervouse system.

The immunomodulatory effects of α-Tocopheryl acetate (alpha-tocopherol acetate) have been demonstrated in vitro, where alpha-tocopherol increases mitogenic response of T lymphocytes from aged mice.

The mechanism of this response by α-Tocopheryl acetate (alpha-tocopherol acetate) is not well understood, however it has been suggested that vitamin E itself may have mitogenic activity independent of its antioxidant activity.

Lastly, the mechanism of action of α-Tocopheryl acetate (alpha-tocopherol acetate)'s antiviral effects (primarily against HIV-1) involves its antioxidant activity.

α-Tocopheryl acetate (alpha-tocopherol acetate) reduces oxidative stress, which is thought to contribute to HIV-1 pathogenesis, as well as to the pathogenesis of other viral infections.
α-Tocopheryl acetate (alpha-tocopherol acetate) also affects membrane integrity and fluidity and, since HIV-1 is a membraned virus, altering membrane fluidity of HIV-1 may interfere with its ability to bind to cell-receptor sites, thus decreasing its infectivity.



PHYSICAL and CHEMICAL PROPERTIES of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
Chemical formula: C31H52O3
Molar mass: 472.743 g/mol
Appearance: pale yellow, viscous liquid
Melting point: –27.5 °C
Boiling point: 240 °C decays without boiling
Solubility in water: insoluble
Solubility: soluble in acetone, chloroform, diethyl ether; poorly soluble in ethanol
Molecular Weight: 472.7 g/mol
XLogP3-AA: 10.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 14
Exact Mass: 472.39164552 g/mol

Monoisotopic Mass: 472.39164552 g/mol
Topological Polar Surface Area: 35.5Ų
Heavy Atom Count: 34
Formal Charge: 0
Complexity: 602
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 3
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Formula : C31H52O3
Molecular weight : 472,74 g/mol
CAS-No. : 58-95-7
EC-No. : 200-405-4

Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point: -28 °C
Initial boiling point and boiling range: 300 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 2,94 mPa.s at 25 °C

Water solubility insoluble
Partition coefficient: n-octanol/water:
log Pow: 12,26 at 25 °C
Vapor pressure: No data available
Density: 0,94 - 0,95 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Water Solubility: 2.9e-06 g/L
logP: 9.19
logP: 10.42
logS: -8.2

pKa (Strongest Basic): -4.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 0
Polar Surface Area: 35.53 Ų
Rotatable Bond Count: 14
Refractivity: 144.53 m³·mol⁻¹
Polarizability: 60.23 ų
Number of Rings: 2
Bioavailability: No
Rule of Five: No
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Chemical Formula: C31H52O3

IUPAC name: 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
InChI Identifier: InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3
InChI Key:ZAKOWWREFLAJOT-UHFFFAOYSA-N
Isomeric SMILES: CC(C)CCCC(C)CCCC(C)CCCC1(C)CCC2=C(C)C(OC(C)=O)=C(C)C(C)=C2O1
Average Molecular Weight: 472.7428
Monoisotopic Molecular Weight: 472.39164553
Molecular Weight: 472.7 g/mol
XLogP3-AA: 10.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 14
Exact Mass: 472.39164552 g/mol
Monoisotopic Mass: 472.39164552 g/mol
Topological Polar Surface Area: 35.5Ų
Heavy Atom Count: 34
Formal Charge: 0

Complexity: 602
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CBNumber:CB5241875
Molecular Formula:C31H52O3
Molecular Weight:472.74
MDL Number:MFCD00072052
MOL File:58-95-7.mol
Melting point: ~25 °C(lit.)
alpha: 3 º (c=2, in ethanol 25 ºC)

Boiling point: 224 °C0.3 mm Hg(lit.)
Density: 0.953 g/mL at 25 °C(lit.)
refractive index: n20/D 1.496(lit.)
Flash point: >230 °F
storage temp.: room temp
solubility: Practically insoluble in water, freely soluble in acetone,
in anhydrous ethanol and in fatty oils, soluble in ethanol (96 per cent).
form: oil or semi-solid
color: yellow
Odor: cryst., odorless
Water Solubility: Merck: 14,9495
Stability: Stable.
Incompatible with strong oxidizing agents.

LogP: 12.260 (est)
CAS DataBase Reference 58-95-7(CAS DataBase Reference)
FDA 21 CFR: 182.8892
Substances Added to Food (formerly EAFUS): ALPHA-TOCOPHEROL ACETATE
SCOGS (Select Committee on GRAS Substances): alpha-Tocopherol acetate
FDA UNII: A7E6112E4N
NIST Chemistry Reference: Vitamin e acetate(58-95-7)
EPA Substance Registry System: D-.alpha.-Tocopheryl acetate (58-95-7)
Molecular form: C31H52O3
Appearance: Light Yellow Think Oil to Off-White Low Melting Solid
Mol. Weight: 430.71
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA



FIRST AID MEASURES of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of α-TOCOPHERYL ACETATE (ALPHA-TOCOPHEROL ACETATE):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available



SYNONYMS:
(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
α-Tocopherol acetate
Vitamin E acetate
Vitamin E acetate
alpha-Tocopherol acetate
58-95-7
Tocopherol acetate
Alfacol
D-alpha-tocopherol acetate
D-ALPHA-TOCOPHERYL ACETATE
Ecofrol
Contopheron
Tofaxin
Econ
Ephynal acetate
(+)-alpha-Tocopherol acetate
Tokoferol acetate
Evipherol
Tocopherex
Tocophrin
Erevit
Vitamin E acetate
alpha-Tocopherol acetate
58-95-7
Tocopherol acetate
Alfacol
Tocopheryl acetate
D-alpha-tocopherol acetate
D-ALPHA-TOCOPHERYL ACETATE
Ecofrol
Contopheron
Tofaxin
Econ
Ephynal acetate
Tokoferol acetate
Evipherol
Fertilvit
Tocopherex
Tocophrin
Erevit
Gevex
Tocopheryl acetate
Combinal E
Epsilan-M
E-Toplex
E-Ferol
Endo E Dompe
Spondyvit
alpha-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Vitamin Ealpha acetate
Vitamin E acetate, d-
Nanotopes
Gevex
(+)-alpha-Tocopherol acetate
Combinal E
Epsilan-M
E-Toplex
E-Ferol
Endo E Dompe
Ephynal
Spondyvit
Juvela
alpha-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Vitamin Ealpha acetate
Vitamin E acetate, d-
Nanotopes
Simmyungsaengmosu
NatAc
Tinoderm E
Natur-E granulate
DL-alpha-Tocopheryl acetate
Lutavit E 50
(+)-alpha-Tocopheryl acetate
CCRIS 4389
(R,R,R)-alpha-Tocopheryl acetate
C31H52O3
EINECS 200-405-4
UNII-A7E6112E4N
(+-)-alpha-Tocopherol acetate
52225-20-4
D-alpha tocoferil acetate
alpha-Tocopherol acetate, all rac
(2R,4'R,8'R)-alpha-Tocopheryl acetate
A7E6112E4N
DL-alpha-Tocopherylacetate
d-Alpha Tocopheryl Acetate
.alpha.-Tocopherol acetate
alpha-Tocopherol acetate, (2R,4'R,8'R)-
EINECS 231-710-0
MFCD00072052
RRR-alpha-tocopheryl acetate
(+)-alfa-tocopherol acetate
alpha-tocopheryl acetate, D-
D-.alpha.-Tocopherol acetate
Tocopheryl acetate, D-alpha-
Vitamin E Acetate (D-form)
UNII-9E8X80D2L0
Vectan (TN)
BRN 0097512
CCRIS 6054
54-22-8
Simmyungsaengmosu
NatAc
Tinoderm E
Fertilvit
Natur-E granulate
DL-alpha-Tocopheryl acetate
Lutavit E 50
Ephynal
Juvela
(+)-alpha-Tocopheryl acetate
CCRIS 4389
(R,R,R)-alpha-Tocopheryl acetate
EINECS 200-405-4
UNII-A7E6112E4N
52225-20-4
D-alpha tocoferil acetate
(2R,4'R,8'R)-alpha-Tocopheryl acetate
A7E6112E4N
DL-alpha-Tocopherylacetate
d-Alpha Tocopheryl Acetate
alpha-Tocopherol acetate, (2R,4'R,8'R)-
RRR-alpha-tocopheryl acetate
(+)-alfa-tocopherol acetate
alpha-tocopheryl acetate, D-
54-22-8
DTXSID1031096
CHEBI:32321
9E8X80D2L0
D-|A-Tocopherol acetate
Tocopherolacetate, alpha-
DL-alpha tocopheryl acetate
EINECS 257-757-7
MFCD00072042
T-3376
d-Vitamin E acetate
Tocopherol acetate [JAN]
.alpha.-Tocopheryl acetate
Tocopherol acetate (JP17)
Tocopheryl Acetate, d-Alpha
CHEMBL1047
NCGC00166253-02
SCHEMBL22298
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
MLS001335985
MLS001335986
DTXCID601356
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-
DTXSID3021356
(+)-.alpha.-Tocopherol acetate
(+)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherylacetate (Vitamin E acetate)
EC 231-710-0
Syntopherol acetate
HMS2230C20
5-17-04-00169 (Beilstein Handbook Reference)
Tox21_111491
Tox21_111564
Tox21_113467
Tox21_303444
ALPHA-TOCOPHEROL ACETATE, D-
ALPHA-TOCOPHEROL ACETATE. D-
LS-245
Rovimix E 50SD
(R,R,R)-.alpha.-Tocopheryl acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
AKOS025117621
NSC 755840
NSC-755840
Tox21_113467_1
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
1406-70-8
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-
.ALPHA.-TOCOPHEROL ACETATE, D-
CAS-58-95-7
NCGC00095255-08
NCGC00166253-01
NCGC00257504-01
DL--Tocopherol acetate
AS-13784
J24.807J
LS-39402
LS-53371
DTXSID1031096
CHEBI:32321
9E8X80D2L0
D-|A-Tocopherol acetate
T-3376
d-Vitamin E acetate
Tocopheryl Acetate, d-Alpha
NCGC00166253-02
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-cromanyl acetate, (+)-
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
6-Cromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
DTXCID601356
alpha-Tocopherol acetate, all rac
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl acetate, (2R-(2*(4R*,8R*)))-
DTXSID3021356
DL-alpha-Tocopherylacetate (Vitamin E acetate)
D-.alpha.-Tocopherol acetate
ALPHA-TOCOPHEROL ACETATE, D-
ALPHA-TOCOPHEROL ACETATE. D-
Vectan (TN)
NSC 755840
NSC-755840
SMR000857327
CAS-52225-20-4
O-Acetyl-alpha-tocopherol
(2R,4'R,8'R)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherol acetate, >=96% (HPLC)
Vitamin E acetate dl-form
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
C13202
D01735
DL-alpha-Tocopherol acetate, analytical standard
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-b- enzopyran-6-ol, acetate
d,l-alpha-Tocopheryl acetate
Eusovit
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-rel-
D-.alpha.-Tocopheryl acetate
Alpha-tocopherol acetate, dl-
Q-201933
vitamin E acetate, (2R-(2R*(4R*,8R*)))-isomer
W-109259
ECA8C22F-B5D3-4B88-A9B7-AF6C600001BB
vitamin E acetate, ((2R*(4R*,8R*))-(+-))-isomer
DL-alpha-Tocopherol acetate, tested according to Ph.Eur.
DTXCID60196594
OptoVit E
SynAC
Rovimix E 50
Alpha Tocopheryl Acetate, United States Pharmacopeia (USP) Reference Standard
alpha-Tocopherol acetate, European Pharmacopoeia (EP) Reference Standard
DL-alpha-Tocopherol acetate, certified reference material, TraceCERT(R)
DL-alpha-Tocopherylacetate (Vitamin E acetate) 10 microg/mL in Acetonitrile
(+)-alpha-Tocopherol acetate, BioReagent, suitable for insect cell culture, ~1360 IU/g
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #
Tocopheryl Acetate, a, Pharmaceutical Secondary Standard; Certified Reference Material
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate
(2R*(4R*,8R*))-(1)-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate
2H-1-benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2R*(4R*,8R*)))-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate,(2R*(4R*,8R*))-(+-)-
All-rac-alpha-tocopheryl acetate for peak identification, European Pharmacopoeia (EP) Reference Standard
Tocopheryl acetate,alpha
Alpha Tocopheryl Acetate
D-ALPHA TOCOFERIL ACETATE (MART.)
D-ALPHA TOCOFERIL ACETATE [MART.]
UNII-WR1WPI7EW8
Copherol 12250
d-|ATocopheryl Acetate
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-
DL--Tocopherol acetate
J24.807J
SMR000857327
CAS-52225-20-4
MFCD00072042
.alpha.-Tocopheryl acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-
D-.alpha.-Tocopheryl acetate
(+)-.alpha.-Tocopherol acetate
(+)-.alpha.-Tocopheryl acetate
DTXCID60196594
(R,R,R)-.alpha.-Tocopheryl acetate
DL-alpha-Tocopherylacetate (Vitamin E acetate) 10 microg/mL in Acetonitrile
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate
EINECS 231-710-0
MFCD00072052
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (2R-(2R*(4R*,8R*)))-
Tocopheryl acetate,alpha
Vitamin E Acetate (D-form)
Tocopheryl acetate, D-alpha-
Alpha Tocopheryl Acetate
D-ALPHA TOCOFERIL ACETATE (MART.)
D-ALPHA TOCOFERIL ACETATE [MART.]
UNII-9E8X80D2L0
BRN 0097512
O-Acetyl-|A-tocopherol
alpha-Tocopherylis acetas
AC1L3BMH
DL-|A-Tocopheryl acetate
.alpha.-tocopherol acetate, dl-
AC1Q1PB2
(+)-|A-Tocopherol acetate
(+)-|A-Tocopheryl Acetate
all-rac-|A-Tocopheryl acetate
DL-ALPHA-TOCOPHEROLACETATE
C31-H52-O3
(R,R,R)-|A-Tocopheryl Acetate
(2R,4'R,8'R)-alpha-Tocopherol acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, acetate, (2R)-rel-
Tocopherol, acetate
Acetate, Tocopherol
ZINC4172337
alpha-tocopherylacetat
FT-0624407
a- tocopheryl acetate
D--Tocopherol acetate
(2R,4'R,8'R)-|A-Tocopherol Acetate
(2R,4'R,8'R)-|A-Tocopheryl Acetate
SC-16401
SC-18242
alpha Tocopherol Acetate
DSSTox_CID_1356
d alpha Tocopheryl Acetate
DL-alpha-Tocopherol acetate, 50% powder form
J10308
DL-alpha-Tocopherol acetate, EP/USP/FCC grade
DSSTox_RID_76104
DSSTox_RID_78863
DSSTox_GSID_21356
DSSTox_GSID_31096
Vitamin E acetate (unlabeled)
VITAMIN E ALPHA ACETATE
(+)- alpha -Tocopherol acetate
TOCOPHERYL ACETATE,D-ALPHA
D-alpha-Tocopheryl acetate, 97%
MolPort-003-928-528
DL-alpha-Tocopheryl acetate, 98%
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate
3, 4- dihydro- 2, 5, 7, 8- tetramethyl- 2- (4, 8, 12- trimethyltridecyl)- 2H- benzopyran- 6- yl acetate
HY-B1278
TOCOPHERYL ACETATE [WHO-DD]
Vitamin E acetate, unspecified form
TOCOPHERYL ACETATE, alpha, D-
s3681
Vitamin E (alpha tocopherol acetate)
2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol acetate
CCG-269474
CS-O-00415
DB14002
.ALPHA.-TOCOPHEROL ACETATE. D-
(+-)-alpha-Tocopherol Acetateacid ester
.ALPHA.-TOCOPHEROL ACETATE [MI]
TOCOPHERYL ACETATE, .ALPHA., D-
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate
[2R*(4R*,8R*)]-()-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
133-80-2
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,6-acetate, (2R)-
AK176402
all-rac-2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-1-benzopyran-6-yl acetate
ALPHA TOCOPHERYL ACETATE (USP-RS)
RRR-ALPHA-TOCOPHERYL ACETATE [FCC]
TOCOPHERYL ACETATE,D-ALPHA [VANDF]
CS-0013056
T2322
VITAMIN E (ALPHA-TOCOPHERYL ACETATE)
A11606
D70796
alpha-TOCOPHEROL ACETATE, UNSPECIFIED FORM
EN300-7398027
A865381
Q364160
Z2681891483
(2R,4'R,8'R)-.alpha.-Tocopheryl acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, acetate, (2R)-rel-
Tocopherolacetate, alpha-
Tocopherol acetate [JAN]
Tocopherol acetate (JP17)
CHEMBL1047
SCHEMBL22298
MLS001335985
MLS001335986
DL-ALPHA-TOCOPHEROLACETATE
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate #
EC 231-710-0
HMS2230C20
(2R,4'R,8'R)-alpha-Tocopherol acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
5-17-04-00169 (Beilstein Handbook Reference)
Acetate, Tocopherol
Tox21_111491
Tox21_111564
Tox21_113467
Tox21_303444
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
AKOS025117621
Tox21_113467_1
D--Tocopherol acetate
.ALPHA.-TOCOPHEROL ACETATE, D-
CAS-58-95-7
NCGC00095255-08
NCGC00166253-01
NCGC00257504-01
AS-13784
alpha Tocopherol Acetate
d alpha Tocopheryl Acetate
DL-alpha-Tocopherol acetate, >=96% (HPLC)
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
D01735
DL-alpha-Tocopherol acetate, analytical standard
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-yl] acetate
3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-b- enzopyran-6-ol, acetate
Q-201933
Vitamin E acetate (unlabeled)
W-109259
VITAMIN E ALPHA ACETATE
ECA8C22F-B5D3-4B88-A9B7-AF6C600001BB
(+)- alpha -Tocopherol acetate
DL-alpha-Tocopherol acetate, tested according to Ph.Eur.
TOCOPHERYL ACETATE,D-ALPHA
HY-B1278
TOCOPHERYL ACETATE [WHO-DD]
Vitamin E acetate, unspecified form
TOCOPHERYL ACETATE, alpha, D-
s3681
Vitamin E (alpha tocopherol acetate)
Alpha Tocopheryl Acetate, United States Pharmacopeia (USP) Reference Standard
alpha-Tocopherol acetate, European Pharmacopoeia (EP) Reference Standard
DL-alpha-Tocopherol acetate, certified reference material, TraceCERT(R)
CCG-269474
DB14002
(+)-alpha-Tocopherol acetate, BioReagent, suitable for insect cell culture, ~1360 IU/g
.ALPHA.-TOCOPHEROL ACETATE. D-
Tocopheryl Acetate, a, Pharmaceutical Secondary Standard; Certified Reference Material
.ALPHA.-TOCOPHEROL ACETATE [MI]
TOCOPHERYL ACETATE, .ALPHA., D-
(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-yl acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, 6-acetate
All-rac-alpha-tocopheryl acetate for peak identification, European Pharmacopoeia (EP) Reference Standard
ALPHA TOCOPHERYL ACETATE (USP-RS)
RRR-ALPHA-TOCOPHERYL ACETATE [FCC]
TOCOPHERYL ACETATE,D-ALPHA [VANDF]
CS-0013056
T2322
VITAMIN E (ALPHA-TOCOPHERYL ACETATE)
A11606
D70796
alpha-TOCOPHEROL ACETATE, UNSPECIFIED FORM
EN300-7398027
A865381
Q364160
Z2681891483
Vitamin E acetate (dimethyl-13C2, acetyl-13C2, 99%; dimethyl-D6, 98%)
(+)-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE
(2R-(2R*(4R*,8R*)))-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRI-DECYL)-2H-1-BENZOPYRAN-6-OL ACETATE
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate, (2R)-
UNII-WR1WPI7EW8 component ZAKOWWREFLAJOT-CEFNRUSXSA-N
Vitamin E acetate (dimethyl-13C2, acetyl-13C2, 99%; dimethyl-D6, 98%)
(+)-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)-6-CHROMANOL ACETATE
(2R-(2R*(4R*,8R*)))-3,4-DIHYDRO-2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRI-DECYL)-2H-1-BENZOPYRAN-6-OL ACETATE
[2R*(4R*,8R*)]-(+-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
12741-00-3
1407-18-7
26243-95-8
2H-1-Benzopiran-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R,8R)-4,8,12-trimetiltridecil]-, 6-acetato, (2R)-rel-
2H-1-benzopirano-6-ol, 3,4-dihidro-2,5,7,8-tetrametil-2-[(4R, 8R)-4,8,12-trimetiltridecil]-, 6-acetato, ( 2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R(4R,8R)]]-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R*(4R*,8R*)]-(.+.)-
2H-1-Benzopyran-6-ol,3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-,acetate, (2R)-
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
Vitamin E acetate; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
α-Tocopherol acetate
(+)-α-Tocopherol acetate
(+)-α-Tocopheryl acetate
D-α-tocopherol acetate
D-α-tocopheryl acetate
Alfacol
Combinal E
Contopheron
E-Ferol
E-Toplex
Ecofrol
Econ
Endo E Dompe
Ephynal acetate
Epsilan-M
Erevit
Evipherol
Fertilvit
Gevex
Juvela
Tocopherex
Tocophrin
Tofaxin
Tokoferol acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
d-Vitamin E acetate
E-vicotrat
Spondyvit
(2R,4'R,8'R)-α-Tocopheryl acetate
(R,R,R)-α-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Tocopheryl acetate
Vitamin Ealpha acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate
Vitamin E acetate
dl-α-Tocopheryl acetate
(+)-.alpha.-Tocopherol, O-acetyl-
(+)-α-Tocopherol acetate
2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate
3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-yl acetate
(+)-alpha -Tocopherol acetate
(+)-alpha -Tocopheryl acetate
(+)-alpha-Tocopherol acetate
(+)-alpha-tocopherol acetate
(+)-alpha-Tocopheryl acetate
(+)-alpha-tocopheryl acetate
(+)-α-tocopherol acetate
(+)-α-tocopheryl acetate
(+-)-alpha-Tocopherol acetate
(+-)-alpha-tocopherol acetate
a-Tocopherol acetate
a-Tocopherol acetic acid
alpha-Tocopherol acetic acid
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, [2R-[2R*(4R*,8R*)]]-
Vitamin E acetate; 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-
α-Tocopherol acetate
(+)-α-Tocopherol acetate
(+)-α-Tocopheryl acetate
D-α-tocopherol acetate
D-α-tocopheryl acetate
Alfacol
Combinal E
Contopheron
E-Ferol
E-Toplex
Ecofrol
Econ
Endo E Dompe
Ephynal acetate
Epsilan-M
Erevit
Evipherol
Fertilvit
Gevex
Juvela
Tocopherex
Tocophrin
Tofaxin; Tokoferol acetate
[2R-[2R*(4R,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol acetate
d-Vitamin E acetate
E-vicotrat
Spondyvit
(2R,4'R,8'R)-α-Tocopheryl acetate
(R,R,R)-α-Tocopheryl acetate
Copherol 1250
Covitol 1100
Covitol 1360
Tocopheryl acetate
Vitamin Ealpha acetate
(+)-alpha -Tocopherol acetate
(+)-alpha -Tocopheryl acetate
(+)-alpha-Tocopherol acetate
(+)-alpha-tocopherol acetate
(+)-alpha-Tocopheryl acetate
(+)-alpha-tocopheryl acetate
(+)-α-tocopherol acetate
(+)-α-tocopheryl acetate
(+-)-alpha-Tocopherol acetate
(+-)-alpha-tocopherol acetate
.alpha.-Tocopherol acetate
Tocopheryl acetate
Tocopheryl acetate,alpha
Alpha Tocopheryl Acetate
Tocopheryl
Jeen vitamin e
Univit-e acetate
O-acetyl--tocopherol
Copherol 1250 c
Aec tocopheryl acetate
Covitol 1100 c
CHEMBL3989859
2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol acetate
[2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
D-α-Tocopheryl acetate
D-ALPHA-TOCOPHEROL ACETATE
Evipherol;dl-alpha-tocopheryl
α-Tocopherol acetate
D-A-TOCOPHERYL ACETATE
D-α-Tocopherol Acetate
D-alpha-Tocopheryl acetate,98%
Econ
Gevex
α-Tocopherol Acetate
(2R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl acetate
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl acetate
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol 6-Acetate
Ephynal Acetate
(+)-α-Tocopherol Acetate
(+)-α-Tocopheryl Acetate
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, 6-acetate, (2R)
Vitamin E acetate; D-Alpha-tocopheryl acetate
D-a-Tocopherol acetate
(R,R,R)-a-Tocopheryl acetate
d-Vitamin E acetate
6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-, acetate, (+)-