Water Treatment, Metal and Mining Chemicals

TWEEN 80
TWEEN 80 also known as Polysorbate 80, is a nonionic detergent commonly used in cell lysis for protein and nucleic acid extraction.
TWEEN 80 is also added to immunoassay buffers such as PBS or TBS.
At room temperature, TWEEN 80 appears as a clear, viscous amber-colored liquid.

CAS number: 9005-65-6
EC number: 500-019-9
Chemical formula: C64H124O26
Molar mass: 1310 g/mol

TWEEN 80 has been used in drug vehicle solution for specific injections in mice and rats.
TWEEN 80 has been used for the determination of esterase activity in bacterial cells.

Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines.
Many detergent varieties are available from several suppliers molecular and biochemical procedures such as protein purification, DNA/RNA isolation, staining and microscopy, electrophoresis, immunoassays, and more.

TWEEN 80 also known as Polysorbate 80, is a nonionic detergent commonly used in cell lysis for protein and nucleic acid extraction.
TWEEN 80 is also added to immunoassay buffers such as PBS or TBS.
At room temperature, TWEEN 80 appears as a clear, viscous amber-colored liquid.

Applications of TWEEN 80:
Bitumen & construction,
Chemicals manufacture,
Emulsification,
Nonwovens.

Uses of TWEEN 80:

Food:
TWEEN 80 is used as an emulsifier in foods.
For example, in ice cream, polysorbate is added up to 0.5% (v/v) concentration to make the ice cream smoother and easier to handle, as well as increasing TWEEN 80 resistance to melting.

Adding this substance prevents milk proteins from completely coating the fat droplets.
This allows them to join in chains and nets, which hold air in the mixture, and provide a firmer texture that holds TWEEN 80 shape as the ice cream melts.

Health and beauty:
TWEEN 80 is also used as a surfactant in soaps and cosmetics (including eyedrops), or a solubilizer, such as in a mouthwash.
The cosmetic grade of TWEEN 80 may have more impurities than the food grade.

Medical:
TWEEN 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the making of the antiarrhythmic amiodarone.
TWEEN 80 is also used as an excipient in some European and Canadian influenza vaccines.
Influenza vaccines contain 2.5 μg of TWEEN 80 per dose.

TWEEN 80 is found in many vaccines used in the United States, including the Janssen COVID-19 vaccine.
TWEEN 80 is used in the culture of Mycobacterium tuberculosis in Middlebrook 7H9 broth.

TWEEN 80 is also used as an emulsifier in the estrogen-regulating drug Estrasorb.
TWEEN 80 is also used in granulation for stabilization of drugs and excipients when IPA binding.

Laboratory:
Some mycobacteria contain a type of lipase (enzyme that breaks up lipid molecules); when these species are added to a mixture of TWEEN 80 and phenol red, they cause the solution to change color, so this is used as a test to identify the phenotype of a strain or isolate.
On RODAC agar plates used in microbiological control, TWEEN 80 counteracts disinfectants often found on sampled surfaces, thereby allowing the microbes found on these surfaces to grow.

TWEEN 80 has a molar mass of 1,310 g/mol and is soluble in water and alcohol.
TWEEN 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics.
TWEEN 80 is a viscous, water-soluble yellow liquid.

TWEEN 80 is an ethoxylated sorbitan ester based on a natural fatty acid (oleic acid).
This ethoxylate is highly effective at forming oil in water emulsions, particularly when used in combination with TWEEN 80 non-ethoxylated precursor, Span 80.
TWEEN 80 (polysorbat 80) is recommended by the European Pharmacopeia as surface-active additive for solubilisation of heavily wettable reagents (1 g/l).

TWEEN 80, (=Polyoxyethylene Sorbitan Monooleate), also known as Polyoxyethylene Sorbitan Monooleate, is a nonionic emulsifier and surfactant and used in cosmetics and foods.
TWEEN-80 is a highly-purified detergent stabilized as a 10% solution (w/v) and packaged under nitrogen in glass ampules or non-leaching HDPE bottles, ensuring TWEEN 80's stability and eliminating the accumulation of peroxides and degradation products.

TWEEN 80 is a 100% bio-based non-ionic surfactant used as versatile emulsifier, dispersing agent, functional carrier fluid, and solubiliser for applications ranging from decorative and industrial coatings to adhesives and liquid colourants.
TWEEN 80 is derived from polyethoxylated sorbitan and oleic acid.

The hydrophilic groups in TWEEN 80 are polyethers also known as polyoxyethylene groups, which are polymers of ethylene oxide.
TWEEN 80 is found in pharmaceuticals and food preparation.

TWEEN 80 is often used in cosmetics to solubilize essential oils into water-based products.
TWEEN 80 is used as an emulsifier in combination with a variety of other hydrophobic emulsifiers to cover a wide range of oil in water, and water in oil emulsion systems.
Individually, TWEEN 80 is an excellent solubilizer of essential oils, wetting agent, viscosity modifier, stabilizer and dispersing agent.

TWEEN 80, 100ml is a nonionic surfactant solution used as a supplement in various culture media in a laboratory setting.
The name TWEEN 80 is synonymous for TWEEN 80.
TWEEN 80, 100ml is a nonionic surfactant derived from sorbitan esters.

TWEEN 80 is used as an emulsifier and dispersing agent when included in various culture media formulas and serves to emulsify and disperse hydrophobic medium components.
TWEEN 80 will also act as a surfactant for samples from surface swabs, for food samples, cosmetics which have high fat content or hydrophobic content.

TWEEN 80 may be included as a component of a dehydrated culture medium i.e 7375 D/E Neutralizing Agar, or TWEEN 80 may be added as a supplement to a medium base without TWEEN.
TWEEN 80, a substance formulated by the reaction of sorbitan fatty acid ester (a nonionic surfactant) with ethylene oxide, is used in many foreign countries, including the U.S. and the EU, where TWEEN 80 acts as an emulsifier, a solubilizer in many foods, including bread, cake mix, salad dressing, shortening oil and chocolate 18.

TWEEN 80 is a hydrophilic nonionic surfactant.
TWEEN 80 is utilized as a surfactant in soaps and cosmetics and also as a lubricant in eye drops.

In food or pharmaceutical products, TWEEN 80 can act as an emulsifier.
TWEEN 80 is an excipient that is used to stabilize aqueous formulations of medications for parenteral administration or vaccinations.

A solubilizing agent acts as a surfactant and increases the solubility of one agent in another.
A substance that would not normally dissolve in a particular solution is able to dissolve with the use of a solubilizing agent.
TWEEN 80 is also known as an emulsifier, which helps ingredients mix together and prevent separation, and water-containing small amounts of salts, and is included in several vaccines licensed in the USA.

TWEEN 80 is a polyethylene sorbitol ester, also know as TWEEN 80, PEG (80) sorbitan monooleate, polyoxyethylenesorbitan monooleate.
TWEEN 80 is widely used in biochemical applications including: solubilizing proteins, isolating nuclei from cells in culture, growing of tubercule bacilli, and emulsifying and dispersing substances in medicinal and food products.

TWEEN 80 has little or no activity as an anti-bacterial agent except TWEEN 80 has been shown to have an adverse effect on the antibacterial effect of methyl paraben and related compounds.
Polysorbates have been reported to be incompatible with alkalis, heavy metal salts, phenols, and tannic acid.
They may reduce the activity of many preservatives.

Features of TWEEN-80:
TWEEN 80—a popular nonionic detergent for use in ELISA, Western blotting and other immunoassay PBS or TBS wash buffers
Accurate—precise 10% detergent solution in ultrapure water
Easy-to-use—solution is simple to dispense and dilute for use
Exceptionally pure—less than 1.0µeq/mL peroxides and carbonyls
Stable—packaged under inert nitrogen gas in glass ampules or HDPE bottles

Pharmacodynamics of TWEEN 80:
Polysorbates are widely used to protect biological drug products from protein unfolding, aggregation, and precipitation during both shipping and handling.
The polysorbates are amphipathic, nonionic surfactants made of fatty acid esters of polyoxyethylene sorbitan.
TWEEN 80 is one of the most common surfactants currently used in the formulation of protein-based biopharmaceuticals

Mechanism of Action:
TWEEN 80 is one of the primary components of protein formulations.
TWEEN 80 inhibits interfacial damage of the protein molecule that undergoes mechanical stress during shipping and handling.

TWEEN 80 also affects the formulation photostability.
Exposure to light of TWEEN 80 results in peroxide generation, which in turn may lead to oxidation of the susceptible amino acid residues in the protein molecule.

One study on rats found that TWEEN 80 increased apical to basolateral membrane permeability of digoxin in Caco-2 cells suggesting that Ps 80 is an in vitro inhibitor of P-glycoprotein.
TWEEN 80 concluded that PS 80 may influence in vivo absorption of P-gp substrates, and this could be translated to human applications.

Metabolism of TWEEN 80:
Polysorbates undergo degradation by auto-oxidation, producing reactive peroxides, in addition to hydrolysis.
Exposure to light of TWEEN 80 leads autoxidation of the alkyl polyoxyethylene chain leading to the production of hydroperoxide derivatives.

The peroxides cause oxidative damage to the protein molecule that makes up the formulation.
The residual peroxides and the rate of peroxide generation as a result of light exposure are found to vary for TWEEN 80 of different grades/from different sources.

Chemistry of TWEEN 80:
TWEEN 80 is derived from polyethoxylated sorbitan and oleic acid.
The hydrophilic groups in this compound are polyethers also known as polyoxyethylene groups, which are polymers of ethylene oxide.
In the nomenclature of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case, the oleic acid (see polysorbate for more detail).

The full chemical names for TWEEN 80 are:
Polyoxyethylene (20) sorbitan monooleate
(x)-sorbitan mono-9-octadecenoate poly(oxy-1,2-ethanediyl)
The critical micelle concentration of TWEEN 80 in pure water is reported as 0.012 mM.

Safety Information of TWEEN 80:

First aid measures of TWEEN 80:

General information:
No special measures required.

After inhalation:
Supply fresh air.
Consult doctor in case of complaints.

After skin contact:
Immediately rinse with water.
If skin irritation continues, consult a doctor.

After eye contact:
Rinse opened eye for several minutes under running water.
Seek medical treatment.

After swallowing:
Rinse out mouth.
If symptoms persist consult doctor.

Firefighting Measures of TWEEN 80:

Suitable extinguishing agents:
Water,
CO2,
Foam,
Powder.

Special hazards arising from the substance or mixture:
Formation of toxic gases is possible during heating or in case of fire.

Advice for Firefighters of TWEEN 80:

Protective equipment:
Wear self-contained respiratory protective device.

Additional information:
Collect contaminated fire fighting water separately.
TWEEN 80 must not enter the sewage system.

Dispose of fire debris and contaminated fire fighting water in accordance with official regulations.
Contain escaping vapours with water.

Accidental Release Measures of TWEEN 80:
Personal precautions, protective equipment and emergency procedures
Do not inhale steams/aerosols.

Environmental precautions:
Do not allow to enter sewers/ surface or ground water.

Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust).
Clean up affected area.

Handling and Storage of TWEEN 80:

Information about storage conditions:
Keep container sealed.

Recommended storage temperature:

Room Temperature:
Store sealed bottle containing TWEEN 80 at 15-30°C.
If opened and not completely utilized, be certain that aseptic dispensing procedures are followed to maintain sterility of the supplement.
Protect from contamination by keeping container tightly closed.

Exposure controls/personal protection:

Ingredients with limit values that require monitoring at the workplace:
Not required.

Additional information:
The lists valid during the making were used as basis.

General protective and hygienic measures:
Immediately remove all soiled and contaminated clothing

Respiratory protection:
Use suitable respiratory protective device only when aerosol or mist is formed.
Filter ABEK.

Hand protection:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

Material of gloves:
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.

Penetration time of glove material:
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

For the permanent contact gloves made of the following materials are suitable:
Nitrile rubber, NBR
Recommended thickness of the material: ≥ 0.11 mm
Value for the permeation: Level ≥ 480 min

As protection from splashes gloves made of the following materials are suitable:
Nitrile rubber, NBR

Recommended thickness of the material: ≥ 0.11 mm
Value for the permeation: Level ≥ 480 min

Eye/face protection:
Safety glasses

Body protection:
Protective work clothing.
Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazourdous substances handled.

Identifiers of TWEEN 80:
CAS number: 9005-65-6
EC number: 500-019-9
Chemical formula: C64H124O26
Molar mass: 1310 g/mol
IUPAC name: Polyoxyethylene (20) sorbitan monooleate

Properties of TWEEN 80:
Boiling point: >100 °C (1013 hPa)
Density: 1.07 g/cm3 (25 °C)
Flash point: >113 °C
pH value: 5 - 7 (50 g/l, H₂O, 20 °C)
Vapor pressure: Viscosity kinematic: 300 - 500 mm2/s (25 °C)
Saponification value: 45 - 55

Hydroxyl value: 65 - 80
Identity (IR): passes test
Description:non-ionic
Form: viscous liquid
mol wt: micellar avg mol wt: 79,000
average mol wt: 1310

Solubility in water: 100 mL/L
Solubility in other solvents: soluble in ethanol, cottonseed oil, corn oil, ethyl acetate, methanol, toluene
Detergent Class: Nonionic polyoxyethylene surfactant
Aggregation Number: 60
Micelle Molecular Weight: 76,000g
Critical Micelle Concentration (CMC): 0.012 mM (0.0016%, w/v)
Dialyzable: No

Specifications of TWEEN 80:
Visual: Slightly hazy to cloudy, colorless solution, free of particulates; may form layers.
Concentration: 10.0±1.0%
Oxidants: ≤1.0µeq/mL
Carbonyls: ≤1.0µeq/mL
Suspended Solids: Residue present must not exceed Residue Reference.

Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)
aggregation number:60
CMC: 0.012 mM (20-25°C)
transition temp: cloud point 65 °C
density: 1.064 g/cm3
HLB: 15

Other Descriptions of TWEEN 80:

Chemical description:
Ethoxylated sorbitan ester

Functions:
Emulsifier

Names of TWEEN 80:

CAS names:
Sorbitan, mono-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.

IUPAC names:
(Z)-Monooctadecenoylsorbitan, Poly(oxy-1,2-ethandiyl)-Deriva te
2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl (E)-octadec-9-enoate
2-[2-[3,4-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl(E)-octadec-9-enoate
2-[2-[3,5-bis(2-hydroxyethoxy)oxolan-2-yl]-2-(2-hydroxyethoxy)ethoxy]ethyl (E)-octadec-9-enoate
Polyoxyethlene sorbitan mono-oleate
Polyoxyethylene (20) sorbitan monooleate
POLYOXYETHYLENE SORBITAN MONOOLEATE
POLYOXYETHYLENE(20) SORBITANMONOOLEATE
Polysorbate 80
Sorbitan monooleate ethoxylated
Sorbitan monooleate ethoxylated (CAS # 9005-65-6)
SORBITAN MONOOLEATE, ETHOXYLATED
Sorbitan monooleate, ethoxylated
Sorbitan monooleate, ethoxylated 2010-12-29
Sorbitan, mono-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs., (Z)-
Sorbitan, monooleate polyoxyethylene deriv.
TWEEN 80

Trade names:
Leunapon-SMO
Polysorbate 80(HX2)

Other names:
Polyoxyethylene-80-sorbitan monooleate
Sorbitan, mono-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.
E number: E433

Other identifiers:
1286269-72-4
1286269-72-4
1340-85-8
1340-85-8
141927-23-3
141927-23-3
178631-96-4
178631-96-4
209796-63-4
209796-63-4
2137448-98-5
2137448-98-5
253447-34-6
253447-34-6
361534-35-2
361534-35-2
37199-23-8
37199-23-8
37280-84-5
37280-84-5
51377-27-6
51377-27-6
541509-66-4
541509-66-4
61723-75-9
61723-75-9
8050-83-7
8050-83-7
900143-89-7
900143-89-7
9005-65-6
9015-07-0
9015-07-0
9050-49-1
9050-49-1
9050-57-1
9050-57-1

Synonyms of TWEEN 80:
TWEEN 80
Montanox 80
Alkest TW 80
PS 80
TWEEN 80
polyethyleneglycol sorbitan monooleate
Polysorbate 80
Sorbitan monooleate, ethoxylated
Sorbitan monooleate, ethoxylated
Tylose
Hydroxyethyl Cellulose; Hydroxyethyl cellulose ether; Hydroxyethyl ether cellulose; Natrosol; Natrasol 250 HHR ; Tylose HS 100000 YP2; Methyl 2-hydroxyethyl cellulose; TYLOSE MH 300 P2; Natrosol 250 M; Natrosol L 250; Natrosol LR; HEC; Natrasol 250 HR; TYLOSE HS 30000 YP2 CAS NO: 9032-42-2
TYLOSE H 15 YG4
TYLOSE H 15 YG4 Tylose H 15 YG4 is a water-soluble, non-ionic hydroxyethyl cellulose, in the form of granules, with standard etherification. Tylose H 15 YG4 provides very good temperature stability, low thickening effects and plasticity, and good binding effects, protective colloidal effects, and particle size control. This grade of hydroxyethyl cellulose (HEC) is particularly well-suited for use in engobe, glaze, powder granuling, slip casting, tape casting, and emulsion polymerisation applications. Tylose H 15 YG4 Technical Datasheet Hydroxyethylcellulose. Tylose H 15 YG4 acts as a thickening agent. Tylose H 15 YG4 is available in granular form with delayed solubility. Tylose H 15 YG4 used in body lotion and sun care products. Claims Thickeners & Stabilizers > Cellulose & Derivatives > Hydroxyethyl Celluloses (HEC, Non-ionic) INCI Names of Tylose H 15 YG4 HYDROXYETHYLCELLULOSE CAS Number of Tylose H 15 YG4 9004-62-0 Tylose H 15 YG4 Hydroxyethylcellulose, with retarded swelling time Product Specification Item Specification Unit Method Texture/Physical form granular Solubility soluble in water of any temperature Ionicity nonionic Moisture, as packed max. 5 % 7130 Ash content, as Na2 SO4 max. 6 % 7140 Particle size <0.500 mm (through 35 mesh) min. 98 % 7010 Viscosity Grade, Höppler falling ball viscometer 15 mPas 7320 1.9% absolutely dry, 20°C, 20°GH Range, Brookfield RV, 20 rpm, sp. 1 150 - 230 mPas 7270 4.75% absolutely dry, 20°C, 20°GH Remarks: PACKAGING AND STORAGE This Tylose-type is supplied in multi-ply paper bags with polyethylene intermediate layer, containing 25 kgs; shrink palletizing is available by ordering a minimum quantity of 1000 kgs. If stored in closed bags under dry conditions, Tylose has a long shelf life. Tylose H 15 YG4 Tylose H grades - water soluble, non-ionic, hydroxyethyl cellulose with standard etherification. Tylose H 15 YG4 Markets of Tylose H 15 YG4: Industrial Processing & Specialty Application of Tylose H 15 YG4: Ceramics, Resin Producer Product Type of Tylose H 15 YG4: Additives Product Category of Tylose H 15 YG4: Rheology Modifiers Problem To Solve : Compostable/Repulpable/Recyclable, Regulatory / Environmental Industries of Tylose H 15 YG4 Personal Care INCIs of Tylose H 15 YG4 Hydroxyethylcellulose Chemicals of Tylose H 15 YG4 Cellulose, 2-hydroxyethyl ether Functions of Tylose H 15 YG4 Binder Emulsion Stabilizer Film Former Stabilizer Viscosity Modifier Categories of Tylose H 15 YG4 Stabilizers & Control Ingredients Chemical families of Tylose H 15 YG4 Cellulose Ethers Cellulose And Derivatives Markets of Tylose H 15 YG4 Beauty & Personal Care Hair Care Skin Care Sun Care Bath And Body Care Nail Care Baby Care Color Cosmetics Treatment Products End uses of Tylose H 15 YG4 Acne Treatments Anti Hair Loss Products Anti Aging Products Anti Dandruff Products Anti Fungal Treatment Tylose Tyloses are outgrowths/extragrouth on parenchyma cells of xylem vessels of secondary heartwood. When the plant is stressed by drought or infection, tyloses will fall from the sides of the cells and "dam" up the vascular tissue to prevent further damage to the plant. Tyloses can aid in the process of making sapwood into heartwood in some hardwood trees, especially in trees with larger vessels.[1] These blockages can be used in addition to gum plugs as soon as vessels become filled with air bubbles, and they help to form a stronger heartwood by slowing the progress of rot.
TYLOSE H 20 P 2
Tylose H 20 P 2 Tylose HEC (hydroxyethyl cellulose/Tylose H-grades) are soluble in water at any temperature. Tylose HEC are nonionic cellulose ethers, which are offered as free flowing powder or in granular form. Many Tylose HEC grades have a retarded solubility which ensures a lump free solution in aqueous systems. General properties Hydroxyethyl cellulose (Tylose H 20 P 2) polymer is a hydroxyethyl ether of cellulose, obtained by treating cellulose with sodium hydroxide and reacting with ethylene oxide. Tylose H 20 P 2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps. They are available as white free-flowing granular powders that easily dissolve in cold and hot water to give transparent solutions with varying viscosities depending on polymer concentration, type and temperature. Natrosol 250 Tylose H 20 P 2 is available in 10 viscosity types, that go from low viscosity values (types L and J) ranging between 0.08 and 0.4 Pas at c = 5 wt.%, intermediate viscosity values (types E, G, K, M) ranging between 0.03 and 6.5 Pas at c = 2 wt.%, arriving to the highest viscosity values (types MH, H, HH) ranging between 0.8 and 5 Pas at c = 1 wt.% (informations are given in the producer booklet Aqualon, 1999). The molecular weight and the degree of polymerization of the Natrosol™ Tylose H 20 P 2 types is directly proportional to their viscosity. Being a nonionic polymer, Natrosol™ is less sensitive to pH changes; however, pH and temperature may slight affect the hydration and dissolution time of the polymer. Tylose H 20 P 2 is a gelling and thickening agent derived from cellulose. It is widely used in cosmetics, cleaning solutions, and other household products. Tylose H 20 P 2 and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids. This process is known as hydrophilization. Tylose H 20 P 2 is also used extensively in the oil & gas industry as a drilling mud additive under the name HEC as well in industrial applications, paint & coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers. Tylose H 20 P 2 is one of the main ingredients in the personal lubricant KY Jelly. It is also a key ingredient in the formation of big bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble. Among other similar chemicals, it is often used as slime (and gunge, in the UK), a gooey substance often used on television and in fundraising events which is poured over individuals with the aim of causing embarrassment. Tylose H 20 P 2 acts as a demulcent by relieving inflammation or irritation and dryness of eyes. It acts as one of the key ingredient and viscosity-enhancing agent to prolong corneal contact time and increase intraocular drug levels. Application Tylose H 20 P 2 is used as a gelling and thickening agent in the development of biostructures for the delivery of hydrophobic drugs. Tylose H 20 P 2 is used in the development of polymer networks and block copolymers useful in separation technology such as capillary electrophoresis and in biofilms and coatings. Tylose H 20 P 2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps. Tylose H 20 P 2 Usage And Synthesis Thickeners and binders Tylose H 20 P 2 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +. Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid. The role of thickener in the aqueous ink is thickened. The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink. Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances. Cellulose substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Tylose H 20 P 2 and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000. The above information is edited by the chemicalbook of Liu Yujie. Chemical properties of Tylose H 20 P 2 This product is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water. Insoluble in common organic solvents. Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding. Different viscosity range of solution can be prepared. Having exceptionally good salt solubility to electrolyte. Description of Tylose H 20 P 2 Hetastarch, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa). When infused as a 6% solution, hetastarch approximates the activity of human albumin. The larger molecular weights, however, increase its intravascular residence time as well as its plasma expansion effects relative to albumin. Hetastarch is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids. Despite these advantages, hetastarch is quite expensive and also has no oxygen-carrying capacity. Chemical Properties light yellow powder Chemical Properties Tylose H 20 P 2 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder. Effect of extent of substitution on solubility When highly polar hydroxyl groups on crystalline cellulose are substituted with hydroxyalkyl groups to manufacture HPC or Tylose H 20 P 2, water solubility initially increases due to a reduction in crystallinity and hydrogen bonding between the cellulose backbone chains. However, as the amount of hydroxyalkyl substitution continues to increase, the polymer becomes increasingly hydrophobic. As shown in Fig. 7.31, the equilibrium moisture content steadily decreases as MS increases from 2.0 to 5.0 for both Tylose H 20 P 2 and HPC. A similar relationship has also been demonstrated for the cloud point.43 An exception to this behavior is polymers with ionic groups in their side chains. In this case, increasing the level of highly polar substituents will increase water solubility. For example, when the DS for sodium carboxymethyl cellulose is increased from 0.7 to 1.2, the equilibrium moisture content at 50% relative humidity increases from 13% to 18%. Regenerated Tylose H 20 P 2 is made by dissolving cellulose xanthate in 4–7% sodium hydroxide and contacting with aqueous sulfuric acid. These steps convert the cellulose xanthate back into cellulose, which may be spun into viscose rayon or cast into films. The fibers are used in textiles (artificial silk), tyre cords, and V belts. The films are used in packaging (Cellophane) or sausage casings. Weiner casings (70% regenerated cellulose, 12% glycerol, and 18% water) are peeled away after the meat emulsion is cooked. Hemp paper casings (23% paper, 46% regenerated cellulose, 21% glycerol, and 10% water) are used in bologna, salami, pepperoni, summer sausage, and liverwurst. Tylose H 20 P 2 moieties are highly reactive, allowing a variety of esters and ethers to be manufactured. Because each anhydroglucose has three hydroxyl groups, the maximum degree of substitution (DS) is three. Purified wood pulp or cotton linters (short fibers) are the industrial sources of ‘chemical cellulose.’ Hydroxyethyl cellulose. Tylose H 20 P 2 Provides effects like thickening, pseudoplastic properties, water retention, protective colloid effects, film forming and a high level of salt tolerance. Offers high gloss, high pigment compatibility, high thickening effect and high water retention. Exhibits moderate wet scrub resistance, anti-spattering, and pseudoplasticity. Used for paints and coatings applications like interior paints, solid paints, exterior paints, tinters, glazes, and silicon resin paints. Hydroxyethylcellulose. Tylose H 20 P 2 Acts as a thickening agent. Tylose H 20 P 2 is available in powder form with delayed solubility. Used in shampoo. Uses disintegrant, binder for tabletting Uses of Tylose H 20 P 2 Tylose H 20 P 2 is a thickener, protective colloid, binder, stabilizer, and suspending agent. It is obtained from wood pulp Copyright 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s). Editorial Review has deemed that any suppressed content does not materially affect the overall learning experience. Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require it. or chemical cotton by treatment with an alkali. Definition A starch derivative containing 90% amylopectin. Production Methods A purified form of cellulose is reacted with sodium hydroxide to produce a swollen alkali cellulose, which is chemically more reactive than untreated cellulose. The alkali cellulose is then reacted with ethylene oxide to produce a series of Tylose H 20 P 2 ethers. The manner in which ethylene oxide is added to cellulose can be described by two terms, the degree of substitution (DS) and the molar substitution (MS). The DS designates the average number of hydroxyl positions on the anhydroglucose unit that have been reacted with ethylene oxide. Since each anhydroglucose unit of the cellulose molecule has three hydroxyl groups, the maximum value for DS is 3. MS is defined as the average number of ethylene oxide molecules that have reacted with each anhydroglucose unit. Once a hydroxyethyl group is attached to each unit, it can further react with additional groups in an end-to-end formation. This reaction can continue and there is no theoretical limit for MS. Brand name Hespan (DuPont Merck) . Pharmaceutical Applications of Tylose H 20 P 2 Tylose H 20 P 2 is a nonionic, water-soluble polymer widely used in pharmaceutical formulations. It is primarily used as a thickening agent in ophthalmic and topical formulations, although it is also used as a binder and film-coating agent for tablets.It is present in lubricant preparations for dry eye, contact lens care, and dry mouth. The concentration of Tylose H 20 P 2 used in a formulation is dependent upon the solvent and the molecular weight of the grade. Tylose H 20 P 2 is also widely used in cosmetics. Safety Tylose H 20 P 2 is primarily used in ophthalmic and topical pharmaceutical formulations. It is generally regarded as an essentially nontoxic and nonirritant material. Acute and subacute oral toxicity studies in rats have shown no toxic effects attributable to Tylose H 20 P 2 consumption, the Tylose H 20 P 2 being neither absorbed nor hydrolyzed in the rat gastrointestinal tract. However, although used in oral pharmaceutical formulations, Tylose H 20 P 2 has not been approved for direct use in food products. Glyoxal-treated Tylose H 20 P 2 is not recommended for use in oral pharmaceutical formulations or topical preparations that may be used on mucous membranes. Tylose H 20 P 2 is also not recommended for use in parenteral products. storage Tylose H 20 P 2 powder is a stable though hygroscopic material. Aqueous solutions of Tylose H 20 P 2 are relatively stable at pH 2–12 with the viscosity of solutions being largely unaffected. However, solutions are less stable below pH 5 owing to hydrolysis. At high pH, oxidation may occur. Increasing the temperature reduces the viscosity of aqueous Tylose H 20 P 2 solutions. However, on cooling, the original viscosity is restored. Solutions may be subjected to freeze–thawing, high-temperature storage, or boiling without precipitation or gelation occurring. Tylose H 20 P 2 is subject to enzymatic degradation, with consequent loss in viscosity of its solutions. Enzymes that catalyze this degradation are produced by many bacteria and fungi present in the environment. For prolonged storage, an antimicrobial preservative should therefore be added to aqueous solutions. Aqueous solutions of Tylose H 20 P 2 may also be sterilized by autoclaving. Tylose H 20 P 2 powder should be stored in a well-closed container, in a cool, dry place. Production methods of Tylose H 20 P 2 1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give Tylose H 20 P 2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour. Squeezed water containing soda to 1: 2.8, pulverized. Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle. Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Tylose H 20 P 2 was obtained. The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging. Then washed with water, centrifugal dewatering, dryed, milled to obtain Tylose H 20 P 2. Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300. 2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze. Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into. In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Tylose H 20 P 2. The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Tylose H 20 P 2. Incompatibilities of Tylose H 20 P 2 Tylose H 20 P 2 is insoluble in most organic solvents. It is incompatible with zein and partially compatible with the following water-soluble compounds: casein; gelatin; methylcellulose; polyvinyl alcohol, and starch. Tylose H 20 P 2 can be used with a wide variety of watersoluble antimicrobial preservatives. However, sodium pentachlorophenate produces an immediate increase in viscosity when added to Tylose H 20 P 2 solutions. Tylose H 20 P 2 has good tolerance for dissolved electrolytes, although it may be salted out of solution when mixed with certain salt solutions. For example, the following salt solutions will precipitate a 10% w/v solution of Cellosize WP-09 and a 2% w/v solution of Cellosize WP-4400: sodium carbonate 50% and saturated solutions of aluminum sulfate; ammonium sulfate; chromic sulfate; disodium phosphate; magnesium sulfate; potassium ferrocyanide; sodium sulfate; sodium sulfite; sodium thiosulfate; and zinc sulfate. Natrosol is soluble in most 10% salt solutions, excluding sodium carbonate and sodium sulfate, and many 50% salt solutions with the exception of the following: aluminum sulfate; ammonium sulfate; diammonium phosphate; disodium phosphate; ferric chloride; magnesium sulfate; potassium ferrocyanide; sodium metaborate; sodium nitrate; sodium sulfite; trisodium phosphate; and zinc sulfate. Natrosol 150 is generally more tolerant of dissolved salts than is Natrosol 250. Tylose H 20 P 2 is also incompatible with certain fluorescent dyes or optical brighteners, and certain quaternary disinfectants which will increase the viscosity of aqueous solutions. Regulatory Status Included in the FDA Inactive Ingredients Database (ophthalmic preparations; oral syrups and tablets; otic and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients. Tylose H 20 P 2 is not currently approved for use in food products in Europe or the USA, although it is permitted for use in indirect applications such as packaging. This restriction is due to the high levels of ethylene glycol residues that are formed during the manufacturing process. Description of Tylose H 20 P 2 Tylose H 20 P 2 is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic character. Pharmacodynamics Tylose H 20 P 2 acts as a demulcent by relieving inflammation or irritation and dryness of eyes. It acts as one of the key ingredient and viscosity-enhancing agent to prolong corneal contact time and increase intraocular drug levels 4. Mechanism of action Interacts with the solid surface through hydrogen bonding to thicken and prolong the formation time of a water-retaining film. Tylose H 20 P 2 acts as a drug carrier or microsphere to entrap other drug molecules and form a viscous gel-like dispersion, enabling drug diffusion across biological membranes 3. Indication of Tylose H 20 P 2 For alleviating surface irritation in topical ocular administrations, such as artificial tear solutions. Tylose H 20 P 2 is also found in topical formulations to aid in more efficient drug diffusion across the membranes. Toxicity May cause chemical pneumonitis in case of inhalation and skin irritation. Animal data suggests potential alteration in female fertility. Tyloses are outgrowths/extragrouth on parenchyma cells of xylem vessels of secondary heartwood. When the plant is stressed by drought or infection, tyloses will fall from the sides of the cells and "dam" up the vascular tissue to prevent further damage to the plant. Tyloses can aid in the process of making sapwood into heartwood in some hardwood trees, especially in trees with larger vessels. These blockages can be used in addition to gum plugs as soon as vessels become filled with air bubbles, and they help to form a stronger heartwood by slowing the progress of rot. Tylose H 20 P 2 is cellulose in which both ethyl and hydroxyethyl groups are attached to the anhydroglucose units by ether linkages. Tylose H 20 P 2 is prepared from cellulose by treatment with alkali, ethylene oxide and ethyl chloride. The article of commerce may be specified further by the viscosity of its aqueous solutions. Hydroxyethyl cellulose Hydroxyethyl cellulose (Tylose H 20 P 2) is a cellulose-derived thickening and the gelling agent used in capsules containing hydrophobic drugs in order to improve dissolution of drugs within GI fluids in a method known as the hydrophilization method. This nonionic and water-soluble polymer is also used in cosmetics, cleaning solutions, and other household products. It will fabricate crystal-clear gel products and thicken the aqueous phase of cosmetic emulsions. Their tendency to lump or agglomerate, when first wetted with water, is a disadvantage associated with Tylose H 20 P 2s and other water-soluble thickeners. The R-grade of Tylose H 20 P 2s facilitates solution preparation without lumping when wetted with water, thus increasing dissolution and total processing times. Safety of Tylose H 20 P 2 Tylose H 20 P 2 is primarily used in ophthalmic and topical pharmaceutical formulations. It is generally regarded as an essentially nontoxic and nonirritant material. Acute and subacute oral toxicity studies in rats have shown no toxic effects attributable to Tylose H 20 P 2 consumption, the Tylose H 20 P 2 being neither absorbed nor hydrolyzed in the rat gastrointestinal tract. However, although used in oral pharmaceutical formulations, Tylose H 20 P 2 has not been approved for direct use in food products. Glyoxal-treated Tylose H 20 P 2 is not recommended for use in oral pharmaceutical formulations or topical preparations that may be used on mucous membranes. Tylose H 20 P 2 is also not recommended for use in parenteral products. Storage Tylose H 20 P 2 powder is a stable though hygroscopic material. Aqueous solutions of Tylose H 20 P 2 are relatively stable at pH 2–12 with the viscosity of solutions being largely unaffected. However, solutions are less stable below pH 5 owing to hydrolysis. At high pH, oxidation may occur. Increasing the temperature reduces the viscosity of aqueous Tylose H 20 P 2 solutions. However, on cooling, the original viscosity is restored. Solutions may be subjected to freeze–thawing, high-temperature storage, or boiling without precipitation or gelation occurring. Tylose H 20 P 2 is subject to enzymatic degradation, with consequent loss in viscosity of its solutions. Enzymes that catalyze this degradation are produced by many bacteria and fungi present in the environment. For prolonged storage, an antimicrobial preservative should therefore be added to aqueous solutions. Aqueous solutions of Tylose H 20 P 2 may also be sterilized by autoclaving. Tylose H 20 P 2 powder should be stored in a well-closed container, in a cool, dry place. Tylose H 20 P 2 has good tolerance for dissolved electrolytes, although it may be salted out of solution when mixed with certain salt solutions. For example, the following salt solutions will precipitate a 10% w/v solution of Cellosize WP-09 and a 2% w/v solution of Cellosize WP-4400: sodium carbonate 50% and saturated solutions of aluminum sulfate; ammonium sulfate; chromic sulfate; disodium phosphate; magnesium sulfate; potassium ferrocyanide; sodium sulfate; sodium sulfite; sodium thiosulfate; and zinc sulfate. Natrosol is soluble in most 10% salt solutions, excluding sodium carbonate and sodium sulfate, and many 50% salt solutions with the exception of the following: aluminum sulfate; ammonium sulfate; diammonium phosphate; disodium phosphate; ferric chloride; magnesium sulfate; potassium ferrocyanide; sodium metaborate; sodium nitrate; sodium sulfite; trisodium phosphate; and zinc sulfate. Natrosol 150 is generally more tolerant of dissolved salts than is Natrosol 250. Tylose H 20 P 2 is also incompatible with certain fluorescent dyes or optical brighteners, and certain quaternary disinfectants which will increase the viscosity of aqueous solutions. Regulatory Status Included in the FDA Inactive Ingredients Database (ophthalmic preparations; oral syrups and tablets; otic and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients. Tylose H 20 P 2 is not currently approved for use in food products in Europe or the USA, although it is permitted for use in indirect applications such as packaging. This restriction is due to the high levels of ethylene glycol residues that are formed during the manufacturing process. Effect of extent of substitution on solubility When highly polar hydroxyl groups on crystalline cellulose are substituted with hydroxyalkyl groups to manufacture HPC or Tylose H 20 P 2, water solubility initially increases due to a reduction in crystallinity and hydrogen bonding between the cellulose backbone chains. However, as the amount of hydroxyalkyl substitution continues to increase, the polymer becomes increasingly hydrophobic. As shown in Fig. 7.31, the equilibrium moisture content steadily decreases as MS increases from 2.0 to 5.0 for both Tylose H 20 P 2 and HPC. A similar relationship has also been demonstrated for the cloud point.43 An exception to this behavior is polymers with ionic groups in their side chains. In this case, increasing the level of highly polar substituents will increase water solubility. For example, when the DS for sodium carboxymethyl cellulose is increased from 0.7 to 1.2, the equilibrium moisture content at 50% relative humidity increases from 13% to 18%. Tylose H 20 P 2 Chemical Properties,Uses,Production Thickeners and binders Tylose H 20 P 2 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +. Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid. The role of thickener in the aqueous ink is thickened. The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink. Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances. Cellulose substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Tylose H 20 P 2 and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000. The above information is edited by the chemicalbook of Liu Yujie. Chemical properties This product is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water. Insoluble in common organic solvents. Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding. Different viscosity range of solution can be prepared. Having exceptionally good salt solubility to electrolyte. Uses 1. This product is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride. Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry. Glazing in ceramic industry and toothpaste binder. Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent. 2. Used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid. Also can be used for filtrate reducer of oil well cement. Cross-linking with the polyvalent metal ions into a gel. 3. As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion. Widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides. There are many uses in oil exploitation and machinery industry. 4. As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc. Production methods of Tylose H 20 P 2 1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give Tylose H 20 P 2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour. Squeezed water containing soda to 1: 2.8, pulverized. Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle. Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Tylose H 20 P 2 was obtained. The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging. Then washed with water, centrifugal dewatering, dryed, milled to obtain Tylose H 20 P 2. Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300. 2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze. Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into. In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Tylose H 20 P 2. The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Tylose H 20 P 2. Description of Tylose H 20 P 2 Hetastarch, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa). When infused as a 6% solution, hetastarch approximates the activity of human albumin. The larger molecular weights, however, increase its intravascular residence time as well as its plasma expansion effects relative to albumin. Hetastarch is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids. Despite these advantages, hetastarch is quite expensive and also has no oxygen-carrying capacity. Chemical Properties light yellow powder Chemical Properties Tylose H 20 P 2 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder.
TYLOSE H 20 P2
Tylose H 20 P2 is water soluble, non-ionic, hydroxyethyl cellulose with standard etherification.
Tylose H 20 P2 is a non-ionic cellulose ether.
Tylose H 20 P2 is easily dispersed and dissolved in water to produce solution of high viscosity.


CAS Number: 9004-62-0
MDL number: MFCD00072770


Tylose H 20 P2 acts as a thickening and stabilizing agent.
Tylose H 20 P2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Tylose H 20 P2 is nonionic cellulose ether and its solution are more tolerant to the presence of cations,anions and organic solvents.


Tylose H 20 P2 exhibits high compatibility with other raw materials such as surfactant.
Tylose H 20 P2 exhibits high compatibility with other raw materials such as surfactant.
Tylose H 20 P2 is a non-ionic cellulose ether made through a series of chemical processes, with the natural polymer celluloses as raw materials.


Tylose H 20 P2 can be dissolved in water to form a transparent viscous solution.
Tylose H 20 P2 is soluble in water at any temperature.
Tylose H 20 P2 is nonionic cellulose ethers, which are offered as free flowing powder or in granular form.


This nonionic, water soluble polymer, Tylose H 20 P2, offers efficient and cost-effective options for making crystal clear gel products.
Tylose H 20 P2 is a nonionic, water-soluble polymer.
Tylose H 20 P2 grades have a retarded solubility which ensures a lump free solution in aqueous systems.


Tylose H 20 P2 is a white to light yellowish, oderless and tastless powder, readily soluble in hot or cold water to form a viscous gel solution.
Tylose H 20 P2 has thickening, adhesion, dispersion, emulsification, film-formation, suspension, absorption, surface activity, salt tolerance, water retention, providing protective colloids and other properties.


Tylose H 20 P2 provides effects like thickening, pseudoplastic properties, water retention, protective colloid effects, film forming and a high level of salt tolerance.
Tylose H 20 P2 will produce crystal clear gel products and thicken the aqueous phase of cosmetic emulsions.
Tylose H 20 P2also has good film-forming ability and surface activity.


Tylose H 20 P2 offers high gloss and pigment compatibility, very high water retention, good anti-spattering, low pseudoplasticity.
Tylose H 20 P2 is a water-soluble synthetic polymer derived from cellulose in which ethylene oxide groups have been added to the hydroxyl groups.
Tylose H 20 P2 forms a non-ionic gel without the effect of electrolyte, suitable for formulations containing electrolyte.


Tylose H 20 P2 exhibits moderate thickening effect and wet scrub resistance.
Tylose H 20 P2 is a non-ionic, water soluble polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Tylose H 20 P2 is derived from cellulose.


Tylose H 20 P2 acts as a thickening and stabilizing agent.
Tylose H 20 P2 is produced by treating reacting alkali-cellulose with ethylene oxide.
Tylose H 20 P2 is recommended that it be added to room temperature water with a neutral pH.


Once hydrated, Tylose H 20 P2 can be heated and the pH can be adjusted as may be needed.
Tylose H 20 P2 is bio-degradable,non-toxic and environmental friendly natural product.
Tylose H 20 P2 is a a non-ionic, water-soluble polymer efficient thickening agent and suspending agent.


Tylose H 20 P2 is like water retention, thickening, suspension, anti-microbial, high salt tolerance, and ion/PH insensitivity.
Tylose H 20 P2 is a white, odorless, tasteless, non-toxic, which is often used as a thickener for methyl hydroxyethyl cellulose or hydroxyethyl cellulose grades in industry agent.


Tylose H 20 P2 exhibits high compatibility with other raw materials such as surfactant.
Tylose H 20 P2 consists of two components: cellulose and hydroxyethyl side chain.
Tylose H 20 P2 is a white, free-flowing granular powder and is made by reacting ethylene oxide with alkali-cellulose.


Tylose H 20 P2 is a water soluble, non-ionic, highly esterified hydroxyethyl cellulose powder.
Tylose H 20 P2 provides enhanced biostability, very high thickening and water retention, moderate foam stabilization and high solution clarity, gloss appearance, pigment compatibility and pseudoplasticity.


Tylose H 20 P2 is an excellent thickening agent for cosmetic and personal care formulations.
Tylose H 20 P2 is white or light yellowish powder.
Tylose H 20 P2 is natural colloids derived from natural fiber.


Tylose H 20 P2 is a gelling and thickening agent derived from cellulose.
Tylose H 20 P2's nature's most abundant biopolymer in plants, wood, and cotton cell walls.
Tylose H 20 P2 is also the most efficient grade of non-ionic thickener available from the manufacturer.


Tylose H 20 P2's beneficial to various construction projects.
Tylose H 20 P2 is a line of nonionic, water-soluble, cellulose based polymers from Dow.
Tylose H 20 P2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.


Tylose H 20 P2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Tylose H 20 P2 is a nonionic, water-soluble polymer.
Tylose H 20 P2 has an exceptional skin feel and is the perfect ingredient to make crystal clear serums for water soluble active ingredients.
Tylose H 20 P2 is odorless, tasteless, and non-toxic in the shape of white to off-white powders or granules.


Tylose H 20 P2 features good water retention and an excellent thickening effect.
Tylose H 20 P2 is a non-ionic, water-soluble polymer derived from cellulose through a series of chemical and physical processes.
Tylose H 20 P2 is easily dissolved in cold or hot water to give crystal-clear solutions of varying viscosities.
Tylose H 20 P2 is soluble in cold or hot water to give clarified solution.



USES and APPLICATIONS of TYLOSE H 20 P2:
Tylose H 20 P2 is used in hair colorants, body lotion, liquid foundation and sun care products.
Tylose H 20 P2 can be also be used to efficiently thicken shampoos, body washes and shower gels.
Tylose H 20 P2 has good rheological properties at different shear rates, and has good workability and leveling, not easy to drop, good splash and sag resistance.


Tylose H 20 P2 is easy to use and provides exceptional skin feel, viscosity and stability.
Tylose H 20 P2 is used for paints and coatings applications like interior paints, exterior paints, solid paints, tinters, silicate paints, distempers, gloss effect top coats, and ready-mixed joint fillers.


Tylose H 20 P2 is characterized by the formation of viscous gels in water, useful for making paints, adhesives for construction, as well as in the paper and oil industry, among others.
With good water retention, thickening, suspension properties, Tylose H 20 P2 offers functional properties and enhance product performancein emulsion-based building materials.


Tylose H 20 P2 is used as a viscosity and rheology modifier, protective colloid, water retention agent, stabilizer and suspending agent, particularly in those applications where a non-ionic material is desired.
Solutions of low molecular weight Tylose H 20 P2 grades have a rheology that is near Newtonian and useful for applications that require a stable viscosity regardless of shear.


Solutions of high molecular weight Tylose H 20 P2, however, behave in a non-Newtonian manner and will have a pseudo-plastic rheology.
This pseudoplasticity makes high viscosity grades of Tylose H 20 P2 an ideal thickener for latex paint applications where the paint must stay on the brush, yet flow out easily upon brushing.


Tylose H 20 P2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps.
Tylose H 20 P2 finds application in formulating hair styling gels, cosmetic products and personal care formulations.


Tylose H 20 P2 has higher and more uniform degree of substitution, improved the enzyme resistance.
Tylose H 20 P2 is non-ionic, water-soluble materials that provide good properties of thickening, suspending, binding, emulsify, film-forming, stabilize, disperse, retain water and etc.


Tylose H 20 P2 is recommended as thickening agent in water-based paint.
Tylose H 20 P2 is a non-ionic soluble cellulose ether, soluble in both cold and hot water, thickening, suspension, adhesion, emulsification, film formation, water retention, protective colloids and other properties, used in coatings.


Tylose H 20 P2 provides excellent thickening efficiency, color development, open time, and superior resistance to biodegradation.
Tylose H 20 P2 also play a role in the emulsion, dispersion, stability and water retention.
Tylose H 20 P2 powders consolidate many advantages and contribute to the construction field.


Tylose H 20 P2 has good rheological properties at different shear rates, and has good workability and leveling, not easy to drop, good splash and sag resistance.
Tylose H 20 P2 has uses in the cosmetics and personal care industries as a gelling and thickening agent.
Tylose H 20 P2 include antiperspirants & deodorants, conditioners, body care, facial care, styling products, sunscreens, liquid soaps, shave gels and foams, wipes (baby and adult), makeup/mascara, AP/Deodorant solids, and lubricant gels.


Tylose H 20 P2 can also be used to make crystal clear, water soluble hair styling gels.
Tylose H 20 P2 is used for the texture paint, latex paint development of a product, product thickening suspension effect is good, high water retention rate, a small amount of addition, low product unit price can reduce the production cost.


Tylose H 20 P2 is suitable for latex paint, oil drilling, adhesives, and personal care.
One of the most important applications of Tylose H 20 P2 and HMHEC are waterborne architectual coatings.
Tylose H 20 P2 is widely used in cosmetics, cleaning solutions, and other household products.


They are either used alone or in combination with other thickeners.
Infact, Tylose H 20 P2 is the most widely used thickener in exterior latex paints because it is compatible with many coating ingredients such as pigments, surfactants, emulsifiers, preservatives, and binders.


Tylose H 20 P2 and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.
Tylose H 20 P2 is used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs.
Tylose H 20 P2 is used in broad range of applications includes cosmetic & personnel care, Paint & coating, oilfield, construction, etc.


Tylose H 20 P2 is a commonly used thickener in paint&coating formulations.
Tylose H 20 P2 is used in paint&coating formulations to increase the viscosity of the paint and to improve its flow and leveling properties.
Tylose H 20 P2 is used as a thickener for a series of organic solvents.


Tylose H 20 P2 is used in various formulations such as film formulations, emulsifiers, flow regulators, and anti-mildew.
Tylose H 20 P2 enhances the viscosity of drilling fluid.
Tylose H 20 P2 acts as a thickening and stabilizing agent.


Tylose H 20 P2 is commonly used in the production of water-based resins, the production of interior paints, the adhesive industry, the polymerization of vinyl acetate, the copolymer lactate with vinyl acrylic acid, the hydraulic fracturing process, the production of nonwovens and detergents, cosmetics, Layering of tiles.
Tylose H 20 P2 is used to obtain the optimum hydration time to prevent agglomeration caused by accelerators greater than the optimal dissolution rate.


Tylose H 20 P2 can be one of the main ingredients in water-based personal lubricants.
Tylose H 20 P2 scientific research team specifically for the texture paint, latex paint development of a product, product thickening suspension effect is good, high water retention rate, a small amount of addition, low product unit price can reduce the production cost.


Tylose H 20 P2 is mainly used in water-based products.
Tylose H 20 P2 polymer is a hydroxyethyl ether of cellulose, obtained by treating cellulose with sodium hydroxide and reacting with ethylene oxide.
Tylose H 20 P2 grades are defined by their molecular weight or more specifically the viscosity of the aqueous solution that they produce at 2% by weight.


Tylose H 20 P2 is one of the main components of the personal lubricant brand known as K-Y Jelly.
Tylose H 20 P2 offers narrow viscosity ranges, consistent viscosity reproducibility, and excellent solution clarities.
Tylose H 20 P2 can also be found in household cleaning products.


Tylose H 20 P2 finds applications as a binder, film former, rheology modifer (thickener), adhesion promoter, dispersion stabilizer, extender and slumping reducer in numerous products including paints, inks, adhesives, cosmetics, personal care products, textiles, cements, ceramics and paper products.
Tylose H 20 P2 offers efficient and cost-effective options for making crystal clear gel products.


In addition to its useful nature as a thickening agent, Tylose H 20 P2 also provides the benefits of a suspension aid, binder, emulsifier, film former, emulsion stabilizer, dispersant, water retention aid, and protective colloid.
Tylose H 20 P2 is also a key ingredient in the formation of large bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble.


Tylose H 20 P2 is widely used in coatings, construction, medicine, food, papermaking and polymer polymerization industry.
Tylose H 20 P2 provides excellent thickening efficiency, color development, open time, and superior resistance to biodegradation.
Tylose H 20 P2 also play a role in the emulsion, dispersion, stability and water retention.


Tylose H 20 P2 acts as a non-ionic thickening agent.
Tylose H 20 P2 is recommended as thickening agent in water-based paint.
Tylose H 20 P2 is also used extensively in the oil and gas industry as a drilling mud additive under the name


Tylose H 20 P2 as well in industrial applications, paint and coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers.
Tylose H 20 P2 is used as a thickener,binder, stabilizer,film forming, protective colloids and suspending agent.


Tylose H 20 P2 is used as adhesives, bonding aids, filling cement admixtures
Tylose H 20 P2 is a hydroxyethyl cellulose powder recommended for use in interior and exterior paints.
Tylose H 20 P2 is used to thicken shampoos, gels, body washes, and add body and after feel to bubble baths, body care products, lotions and creams.


Tylose H 20 P2 is used in rinses, hair conditioner, hair gel and shaving products.
Tylose H 20 P2 is not an emulsifier and will not emulsify oils into water.
Tylose H 20 P2 can be used in building materials, paints industry, petrochemicals, synthetic resin, ceramic industry, pharmaceutical, food, textile, agriculture, cosmetics, tobacco, ink, papermaking and other industries.


Tylose H 20 P2 is a cellulose ether that is primarily used as a thickener for water-based paint, ink, and adhesive formulations.
Tylose H 20 P2 can also be used to make crystal clear, water soluble hair styling gels.
The applications for Tylose H 20 P2 range but in the industrial space it is primarily used for general thickening applications in latex paints, household cleaners and tape-joint compounds.


Tylose H 20 P2 is used as a non-ionic cellulose thickener, usually to enhance viscosity, increase concentration by absorbing water, increase viscosity, increase stability, increase degradability, and increase gloss.
Tylose H 20 P2 is used as coatings and optical brightener additives, coating polymers, filter control additives
Tylose H 20 P2 is used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier


-Aplications of Tylose H 20 P2:
• Paint and coating thickener.
• Preparation of water-based latex paints.
• Preparation and synthesis of binder.
• Extraction of petroleum.
• Construction and building materials.
• Manufacture of paper.
• Binder.
• Adhesive.


-Recommended fields of application of Tylose H 20 P2:
*Interior paints
*Exterior paints


-Uses of Tylose H 20 P2:
*Construction uses of Tylose H 20 P2: Cement mortar, Concrete mix, Thickening
*Dyeing: Latex paint, polymer emulsifying, Thickening, water retention, retarding
*Papermaking:Sizing agent,Thickener, water-retaining
*Cosmetic:Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil:Drilling well, completing fluids,Water retention, Thickening,Control of fluid loss


-Uses of Tylose H 20 P2:
*solubility
*thickening effect
*surface activity


-Typical recommended for thickening and hydration using Tylose H 20 P2.
Disperse Hydroxyethyl cellulose in solution, usually water, and by stir vigorously or using a blender.
Continue to hydrate the HEC in water until completely dissolved.
The thickening will be delayed, this is normal and how the product is designed to work.
(Stir until all particles are dissolved.)
This process allows the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.


-Recommended Field Application of Tylose H 20 P2:
*Interior paints
*Solid paints
*Exterior paints
*Silicon resin paints
*Tinters
*Glazes


-Application Field of Tylose H 20 P2:
*Interior wall latex paint
*Exterior wall latex paint
*Real stone paint
*Texture paint


-Application properties of Tylose H 20 P2:
Tylose H 20 P2 is majnly recommended for ready mixed joint compounds (RMJC).
Tylose H 20 P2 provroes a very creamy and easy wôrkability.
Usually Tylose H 20 P2 is used in combination with Tylose MHPC or MHEC grades to Typical data further improve the workability


-Applications of Tylose H 20 P2:
*Water-based paint
*Polymerization
*Cosmetics
*Others


-Application Field of Tylose H 20 P2:
*Interior wall latex paint
*Exterior wall latex paint
*Real stone paint
*Texture paint



BENEFITS OF TYLOSE H 20 P2:
Tylose H 20 P2 is used as a high performance non-ionic thickener, water-retaining aid and rheological additive in all types of water-based paints and surface coatings, adhesives and many other water-based industrial products.
Tylose H 20 P2 gives these systems excellent rheological properties.
*Additional purification to reduce ash content Excellent salt tolerance
*Imparts slip and lubricity
*Ability to create clear formulations
*Stabilizes emulsion systems
*Surface-treated to aid incorporation into water
*Vegan suitable



IMPORTANT PROPERTIES OF TYLOSE H 20 P2:
Tylose H 20 P2 can be used as a non-ionic surface active agent.
In addition to thickening, suspending, adhesion, emulsifying, film-forming, dispersing, water-retaining and providing protective colloid properties, but also has the following properties.
1. Tylose H 20 P2 is soluble in hot or cold water, does not precipitate by heat or boiling, and enables it to have a wide range of solubility and viscosity characteristics, as well as non-thermal gelation;
2. Tylose H 20 P2’s non-ionic itself and can coexist with a wide range of other water-soluble polymers, surfactants, and salts, a fine colloidal thickener for the solution containing a high concentration of electrolytes;
3. Tylose H 20 P2's water retention capacity is twice as that of methyl cellulose, and it has better flow-regulating property;
4. Tylose H 20 P2 is stable in viscosity and prevented from mildew.
Tylose H 20 P2 enables the paint to have good can-opening effects and better leveling properties in construction.



PROPERTIES AND APPLICATIONS OF TYLOSE H 20 P2:
Tylose H 20 P2 is an important non-ionic, water-soluble cellulose derivative.
Tylose H 20 P2 is a completely odorless, tasteless, and non-toxic white to light-yellow powder that readily dissolves in hot and cold water but is insoluble in most organic solvents.
When dissolved in water, Tylose H 20 P2 forms a transparent viscous solution which has a non-Newtonian behavior.

The hydroxyl groups of Tylose H 20 P2 present in the side chains can be reacted with hydrophobic moities to modify the properties of HEC.
For example, attaching polyether chains onto the cellulose (alkoxylation) yields hydrophobically modified Tylose H 20 P2.
Tylose H 20 P2 is an associative thickener that forms a reversible three-dimensional supramolecular network in solution through intra- and intermolecular associations of the hydrophobic groups.



PROPERTIES AND FUNCTIONALITY OF TYLOSE H 20 P2:
*Benefit from the non-anionic nature, Tylose H 20 P2 is high stable to broad range of salt, soluble and high resistance even in high brine concentration.
*High-performance thickening, efficient high viscosity build up
*Outstanding pseudoplasticity, Unique shear-thinning characteristic and viscosity reversible
*Film-forming agent, protective colloid action.
*Water retention,maintain water content at formulation
*Excellent compatibility to broad range of water soluble materials or ingredients



PROPERTIES OF TYLOSE H 20 P2:
Tylose H 20 P2 is a free-flowing powder or granules that range in color from white to slightly yellowish.
Tylose H 20 P2 is odorless and tasteless and contains residual moisture determined by the conditions of production, as well as a small amount of residual salts.
Tylose H 20 P2 can also contain other additives which, for example, regulate the solubility and dispersibility or purposefully influence the development of viscosity.
Depending on the field of application, Tylose H 20 P2 is offered in unmodified and modified form.
The most important properties of Tylose H 20 P2:
*solubility
*thickening effect
*surface activity



FEATURE OF TYLOSE H 20 P2:
*Tylose H 20 P2 dissolves readily in both cold water and hot water.
*Aqueous solutions of Tylose H 20 P2 are stable and do not gel at either high or low temperatures.
*Tylose H 20 P2 is a nonionic cellulose ether that remains chemically and physically stable over a wide pH range.
*Tylose H 20 P2 shows excellent performance as athickener, as a water-retention agent, as a suspending and dispersing agent, and as a protective colloid.
*Tylose H 20 P2 can be stored for log periods without degrading significantly, and in aqueous solutions its viscosity remains stable.
*Tylose H 20 P2 is a water-soluble polymer synthesized by the reaction of ethylene oxide with cellulose.
Aqueous solutions of Tylose H 20 P2 have excellent characterisstics for applications as thickeners, water-retention agents, suspending and dispersing agents, and as protective colloids.
In the synthesis of hydroxyethylcellulose, the avarage number of moles of ethylene oxide that combines with each mole of cellulose (MS) is used as an index.
The value of MS in Tylose H 20 P2 is controlled within 1.5 to 2.5.



PHYSICAL AND CHEMICAL PROPERTIES OF TYLOSE H 20 P2:
Tylose H 20 P2 is soluble in both cold and hot water, but under normal circumstances does not dissolve in most organic solvents.
When the pH value is within the range of 2-12, the change in viscosity is small, but if beyond this range, the viscosity will decrease.
The surface-treated Tylose H 20 P2 can be dispersed in cold water without agglomeration, but dissolution rate is slower, and generally it requires about 30 minutes.
With heat or adjusting the pH value to 8-10, it can be rapidly dissolved.



SPECIFICATIONS OF TYLOSE H 20 P2:
- Tylose H 20 P2 provides viscosity at 3,400-5,000 mPa s (cPs) at 1% in water.
- Tylose H 20 P2 melts and forms a gel at about 70 degrees and dissolves well at pH higher than 7 (use an alkali such as Triethanolamine helps to raise the pH value, after dissolving, can adjust the pH later)
- Tylose H 20 P2 can be used in formulations that are acidic down to pH 3 and alkaline up to pH 9.
- Tylose H 20 P2 has no smell



PHYSICAL and CHEMICAL PROPERTIES of TYLOSE H 20 P2:
Appearance: white or similar to white powder
Moisture(%): Max. 8.0
PH: 6.0-8.5
Apparent Density: 0.30-0.50 g/ml
Appearance Form: powder
Color: beige
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available

Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Chemical formula: variable
Molar mass: variable
Melting point: 140 °C (284 °F; 413 K)
Appearance: white or similar to white powder
Moisture(%): Max. 8.0
PH: 6.0-8.5
Apparent Density: 0.30-0.50 g/ml

Type: Interior / Exterior / Solid Paints
Form: Powder
Appearance: white powder
Etherification: high etherification
Particle size: powder
Delayed solubility: yes
Biostability: yes
Viscosity level (according to Höppler): hydroxyethyl cellulose
Viscosity: 4200 - 5500 mPa-s
solution pH: 6-8.5
Moisture content (packed): <6%
Ash (calculated as Na2SO4): <6%
particle size: no more than 10%
Esterification (MS): 2.70
swelling time: 20 minutes.
Bulk densit: 0.45g/l
Lower explosion limits: 30 g/m³
Upper explosion limits:
Density (at 20 °C): 1,1-1,5 g/cm³
Water solubility: (at 20 °C) > 10 g/L

Partition coefficient: log POW < 0
Ignition temperature: > 460 °C
Auto-ignition temperature > 120 °C
Explosive properties The product is considered non-explosive.
Bulk density: 200 - 600 g/l
Conbustion class: 5
Smoulder temperature: 280 °C
pmax: 10 bar
KSt: < 200 bar*m/s
Dust explosion class: ST1
Minimum ignition energy: > 10 mJ
Physical state: Powder
Colour:Whitish
Odour: characteristic
Test method
pH-Value (at 20 °C): 6 - 8 10 g/l
Changes in the physical state
Melting point: n.a.
Initial boiling point and boiling range: n.a.
Flash point: n.a



FIRST AID MEASURES of TYLOSE H 20 P2:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TYLOSE H 20 P2:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of TYLOSE H 20 P2:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of TYLOSE H 20 P2:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of TYLOSE H 20 P2:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of TYLOSE H 20 P2:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
NATROSOL
ETHOCEL
Hydroxy Ethyl Cellulose
Natrosol 250 HR (SCS 1216)
CELLOSIZE QP 100 MH
CELLOSIZE QP 30000 H
NATROSOL 250 HHBR
NATROSOL 250 HHR
CELLOSIZE HEC-10
NATROSOL 250 HR PC
CELLOSIZE QP 300
HEC HV 250 HHR-P
Cellosize QP 4400 H
Natrosol 250 HR
Cellosize QP 52000 H (use 1M081)
Natrosol 250 MHBR
Cellosize QP 30000 H
Natrosol 250 LR
Hydroxyethyl cellulose, modified
Tylose FL 6002
Hydroxy ethylcellulose
water soluble
Hydroxyethyl cellulose
non-ionic watersolu.cellulose ethers
Hydroxyethylcellulose (HEC)
nonionic, water-soluble polymer
Natrosol 250 L
Cellosize QP 15000
Cellosize QP 52000
Cellosize QP 100 MH
Cellosize QP 300
Cellosize QP 09
Hydroxyethyl cellulose, granular powder
Cellosize QP 4400
Cellosize QP 300
Cellosize QP 40, Natrosol 250 GR
Natrosol 250 HHR
Modified cellulose ether
Cellulose, modified
hydroxypropyl methylcellulose
Hydroxyethyl cellulose
hydrophobically modified
Hydroxypropyl methylcellulose
Hydroxyethyl cellulose
Cellosize EP 09
Cellosize EP 300
Tylose H 100.000 YP
Tylose H 20 P2
Tylose H 20 P
Natrosol 250 HHBR
Ethylhydroxyethylcellulose
Natrosol Slurry ADX 151
Hydroxy ethyl cellulose
Hydroxyethyl cellulose
Hydroxy ethylcellulose slurry
Ethylhydroxyethyl cellulose
Bermocoll CST 257
Hydroxypropyl methyl cellulose
Hydroxypropyl methylcellulose 90%
Hydroxypropyl methylcellulose
Bermocoll EHM 100 ED
Cellosize ER 30 M
Hydroxyethylcellulose
Hydroxyethyl cellulose, Pure
Natrosol 250 HHXR
Tylose H 60000 YP2
Hydroxyl ethyl cellulose
Hydroxyethylcellulose, water soluble
Natrosol 250 GR (only for Sico)
Hydroxyethylcellulose, rheology modifier
Tylose H 300 P2
Hydroxyethylcelluose, with retarded swelling time
Cellosize QP 09L
Natrosol 250 MXR
Cellosize QP-3L
Cellulose, 2-hydroxyethyl ether
Cellulose hydroxyethylate
Natrosol
Cellosize WP 4400
Natrosol 250HR
Tylose H 300
Glutofix 600
Cellosize QP 4400
Cellulose hydroxyethyl ether
Natrosol 250HX
2-Hydroxyethyl cellulose
Hydroxyethyl cellulose ether
Hydroxyethyl ether cellulose
Natrosol 240JR
Natrosol 250M
Natrosol 250G
2-Hydroxyethyl cellulose ether
Cellosize QP 1500
Hercules N 100
Cellosize WP 300
Natrosol 250HHR
Cellosize WP 300H
Cellosize WP 400H
Cellosize UT 40
Natrosol 300H
Cellosize WP
Natrosol 250H
Natrosol 250
Cellosize QP 10000
Cellosize QP 15000
HEC
Cellosize 4400H16
Cellosize WPO 9H17
Cellosize QP
Tylose H 20
OETs
BL 15
HEC-Al 5000
Natrosol LR
J 164
Natrosol 250HHP
Natrosol 250H4R
Natrosol 250MH
Cellosize QP 3
Natrosol 150L
Natrosol 180L
Fuji HEC-BL 20
AW 15 (polysaccharide)
Cellosize QP 30000
Natrosol 250HH
AW 15
Natrosol 180HH
Natrosol 300HH
AH 15
Cellosize WP 09
Natrosol 250LR
Natrosol 250MR
Cellosize QP 300H
Cellosize
HEC-Unicel
Natrosol 250R
Cellosize QP 52000
Fuji HEC-AL 15
HEC-Unicel QP 9
Unicel QP 52000H
Unicel QP 100MH
Unicel QP 300H
Hydroxyethyl cellulose
Fuji HEC-A 5000F
Fuji HEC-AW 15F
Tylose H 300P
Cellosize QP 300
Natrosol 250L
Natrosol GXR 250
Natrosol 250HBR
Natrosol MHR
HEC-BL 15
Natrosol 150GXR
Cellosize WP 09L
Natrosol 250J
Culminal HEC 5000PR
HEC-A 5-25CF
HEC-AH 15
Natrosol 250GR
Natrosol 250MHR
Walocel HT 6.000PFV
Telhec
Natrosol 250HHW
Cellosize TJC 500
HEC-Unicel QP 09L
HEC-Unicel QP 300H
HEC-Unicel QP 30000H
SP 250
SP 407
Fuji HEC-HP
Tylose H 100000
HEC 10A
Fuji HEC-AG 15
Natrosol 250 H4BR
Natrosol MR
Cellobond 25T
Cellobond HEC 5000
Cellobond HEC 400
Cellobond HEC 15A
Cellosize WP 4400H
Fuji HEC-SY 25F
Cellosize QP 40
Cellosize QP 4400H
Cellosize DP 40
Daicel SP 500
Cellosize WP 02W1062R
Cellosize QP 5200W1930X
Cellosize QP 52000H
Cellobond 45000A
Natrosol 250HHX
Daicel SP 600
HEC-SP 200
Cellosize HEC-QP 09L
QP 100M
HEC 250H
Daicel EP 850
Glycol cellulose
Cellosize QP 100M
Cellosize QP 40L
Natrosol 250MXR
AX 15
SP 250 (cellulose)
HEC-SE 750
HEC-QP 9H
Cellosize QP 15000H
SE 850K
Daicel EP 500
Natrosol MR 250
Cellosize QP 15MH
Cellosize OP 09
Natrosol HR 250
Cellosize WPO 9H
Cellosize HEC 4400
Natrosol 250LV
QP 10000
QP 30000
Tylose H 20P
HEC-Unicel QP 4400H
BL 15 (cellulose derivative)
Natrosol GXR
Tylose H 10
Daicel SP 750
Culminal HEC 30000
Unicel QP 4400
Unicel QP 15000
Natrosol 250NHR
Cellosize WP 09H
HEC-SE 850
Sanhec
Tylose H 4000
HEC-AL 15
SP 200
Tylose H 30000YP
H 30000YP
HEC Daicel SE 850K
Daicel SE 850K
Tylopur H 300
Admiral 3089FS
Daicel SP 800
Fuji HEC-AX 15F
Metolose 90SEW
Natrosol 250HB
HEC-SP 400
Natrosol 99-250L-NF
HEC-QP 4400
HEC-QP 100MH
Tylomer H 200
Tylomer H 20
Daicel SP 200
Daicel SP 550
Tylose H 15000YP2
HEC Daicel SE 600
HEC Daicel SE 900
Daicel SE 600
Daicel SE 900
HEC-QP 100M
Hyetellose
Daicel SP 400
FL 52
Cellosize QP 100MH
Tylose H 6000XP
Cellosize QP 09H
Natrosol 250HHBR
Aqualon HEC
Daicel SP 850
QP 52000
AL 15
QP 300H
Natrosol 250HHXR
Natrosol HHR 250
SP 400
Cellosize HEC-QP 30000H
Cellosize HEC-QP 15000H
Cellosize HEC-QP 52000H
Natrosol 250MP
Cellosize QR 4400H
Cellosize QP 3L
Natrosol 250K
Natrosol HHXR
HEC-SP 550
Natrosol Plus 250HHX
QP 09H
QP 4400
QP 15MH
QP 30MH
Fujichemi HEC-CF-G
Tylose H 20P2
HEC-SP 900
SP 900
HEC-SP 600
Tylose H 10000YP2
SP 550
250LR
250HR
Fujichemi HEC-AX 15F
EP 850
Cellosize HEC-QP 4400H
Tylose H 10G4
HEC-QP 15000H
HEC-QP 4400H
Natrosol 250MBR
HEC 850SE
Tylose H 4000P2
HEC Daicel SP 200
SE 900
SP 500
Sulfatsell
Fujichemi HEC CF-W
Fujichemi HEC CF-V
Halad 9
Halad 23
Fujichemi HEC-SY 25
Fuji-Chem HEC-SY 25
MR 250HR
Liporamnosan
3089FS
Tylose H 4000P
HEC-SP 250
Natrosol 250JR
Fujichemi HEC-SZ 25
Natrosol 250GXR
Cellosize HEC-QP 100M
Natrasol
Cellosize PCG 10
Tylose H 15YG4
Tylose H 180YG4
Tylose H 200YG4
Natrosol HHBR 250
SX 25F
SZ 25F
Tylose H 30000YP2
Tylose H 60000YP2
CF-G
CF-W
Natrosol 250HR-CS
Tylose H 10000G4
Natrosol QP 300
QP 300
HEC 210HHW
Cellosize WP 40
WP 40
SE 400
HEC Daicel SE 400
HEC Daicel 900
HEC 600
Tylose H 100000YP
HEC-QP 300
Fujichemi HEC
HBR 250
250HBR
Admiral FPS 3089
Liqui-Vis EP
Cellosize ER 4400
HEC-SE 900
Natrosol HIVIS
Sulfatsell 2D
Cellosize H 15000YPZ
Cellosize WP 09B
HEX 250HR
SE 850
Tylose H 6000YP2
ER 30M
QP 15000H
Aqualon LR 250
Cellosize QP 09L
Natrosol HX Pharm
Tylose H 10000P2
Bermocoll E 411
HEC Daicel SP 600
H 300YP2
Natrosol 25OHX
Natrosol 259MXR
LF 15
J 164 (polysaccharide)
Natrosol 250H4BXR
Natrosol LR 250
Sulfatsell 25
Daicel SE 850
Tylose H 300YP2
SE 390
Cellosize WPO 3H
HEC Daicel SP 500
Cellosize ER 15M
Sanhec H
HEC SE 600
HEC Daicel SP 900
QP 52000H
Natrosol HHX
Natrosol HEC 250HHX
Cellosize ER 15
HEC Daicel SE 500
Tylose H 4000YG4
Tylose E 60505
Natrosol 250KR
Tylose 10000P
Cellosize HEC-QP 100MH
Natrosol G
RT 6000
SH 15
AH 15L
SY 25
Tylose H 20000YP2
HEC Daicel SP 850
HEC-SP 500
HEC-SP 850
Fuji HEC-SG 25F
Tubicoat HEC
451F
HEC Daicel SE 850
Natrasol 250HHBRPA
Aldiamed
HEC SE 400
HEC SE 500
HEC-SE 550
QP 15000
HS 100000YP2
Daicel SP 900
HEC Daicel SP 550
EM 30M
Natrosol MHBR
Cellosize QH 100000
ER 52M
Natrosol 250MHBR
Natrosol L
Natrosol M
QP 100MH
250HHBR
Natrosol 250HXR
Natrosol MX 250
HEC-CF-G
QP 30000H
HEC 250HX
HEC 250M
CF-X
HEC-ER 5200
ER 5200
ER 4512
Cellosize HEC-QP 52000H3
QP 4400H
HS 30000
HS 30000YP2
Collaxim SF
Chrysoplast V 90
Cellosize WP 3000
Cellosize QP 20000
HEC CF-V
HSYP 30000R
HYSP 100000
EE 820
Natrosol 250E
Sanhec M
HEC-AX 15
Tylose H 4000G4
Natrosol AT 250
HEC 30000
Natrosol 250M Pharm
Cellosize DSC
Tylose H 27NG4
PF-VMTs
Tylose H 22P
Cellosize HEC Spatter Guard 100
Cellosize HEC 15
3000M
YLT 999
Nexton IP 5A
SP 600
EP 30M
HEC-AW 15F
Natrosol 25OHBR
Cellosize ER 30M
Cellosize 52000H
QP 09L
CZ 010
Natrosol HBR 250
P 330A
Cellosize EP 09
B 30K
HEC 250
HECSZ 25F
B 100K
Tylose H 10YG4
Tylose H
30000S
Natrasol 250
Natrosol L Pharm
HEC-AG 15F
SW 25F
Natrosol 250HHX Pharma
EBS 481PQ
HEC Daicel 850
TF 30000
Combizell DE 6000
HEC-TF 30000
Antifoam RD 10
YT 30000
Fujichemi CF-V
Natrosol HEC 250HR
Sanhec L
250MBR
HHBR 250
H 250
HS 10W
HEC CF-Y
Cellosize HEC-QP 4400
Natrosol HEC
HE 6D
TF 30000S
HEC Daicel SE 550
Daicel SE 550
SE 600
SE 550
Aqualon NP 330
NP 330
HEC 250HBR
HEC-Q 52000
AL 15F
Natrosol HEC 250MR
Walocel MKX 15000PF01
30000YP2
Cellosize HEC
Hecellose H 30K
HD 30000
Tylose HX 6000YG4
HS 30000PY2
HS 6000YP2
Tylose HS 6000YP2
HEC 6000
2500HEC
Natrosol HH
Tylose HS 30000YP2
MHS 60000YP4
MHS 60000YP2
Cellosize HEC-EP 300
Cellosize EP 300
Natrosol 250HR-PC
B 15K
ReCell HE 10MD
HEC 60000
HE 6000SE
BR 30000H
Tylose HEC
Sulfacell 150
Cellulose 893
100000YP2
C 3061
Cellosize HEC AM 103
B 30
2-Hydroxyethyl cellulose
Cellulose, hydroxyethyl ether
Hydroxyethylcellulose
2-Hydroxyethyl cellulose
Hyetellose
Natrosol
Cellosize
Hydroxyethyl cellulose
HS 100,000 YP2
Cellulose, 2 – hydroxyethyl ether
hydroxyethyl cellulose
Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
Hydroxyethyl Cellulose,2-hydroxyethylcelluloseether
ah15
aw15(polysaccharide)
aw15[polysaccharide]
bl15
cellosize
Hydroxyethyl cellulose – Viscosity 1500 ~ 2500
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol




TYLOSE H 300 NG4
Hydroxyethyl cellulose; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;thickener ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE H 300 P2
Tylose H 300 P2 is water soluble, non-ionic, hydroxyethyl cellulose with standard etherification.
Tylose H 300 P2 has low viscosity methyl hydroxyethylcellulose, soluble in cold water and insoluble in hot water or organic solvents.


CAS Number:68957-96-0


Tylose H 300 P2's aqueous solutions have a neutral pH that makes it a high-quality binder for tempera and gouache, as well as a good adhesive for restoring paper and graphic works.



USES and APPLICATIONS of TYLOSE H 300 P2:
Tylose H 300 P2's aqueous solutions have a neutral pH that makes it a high-quality binder for tempera and gouache, as well as a good adhesive for restoring paper and graphic works.
Tylose H 300 P2 is used thickener.
Tylose H 300 P2 is used Emulsion condensing agent, adhesive in the restoration of paper and photographic documents, fabric gluing.


-Application Performance ofTylose H 300 P2:
*Building Materials
*Consistency development
*Final consistency
*Sag resistance
*Water demand
*Water retention
*Influence on cement hydration
*Heat stability
*Drilling Industry
*Thickening: low
*Thermal stability
*Salt compability
*Cement retardation



ADVANTAGES OF TYLOSE H 300 P2:
When in contact with water, Tylose H 300 P2 offers a variety of properties, including: regulating the consistency (viscosity) of vinyls and pastes, reducing splashes; regulates the water retention capacity, thus improving the drying process and film formation; reduces sedimentation of fillers and pigments, avoiding phase separation; reinforces the adhesive and binding power between loads as well as PVA's, increasing their degree of adhesion.
Tylose H 300 P2 is used for resistant to microorganisms.
Tylose H 300 P2 is used for self leveling compounds.



PHYSICAL and CHEMICAL PROPERTIES of TYLOSE H 300 P2:
Appearance: powder
Etherification: standard
Particle size: powder
Delayed solubility: yes
Level of viscosity: according to Höppler: 300 mPa•s
Composition: hydroxyethyl cellulose
Appearance: white powder
Etherification: standard etherification
Particle size: powder
Delayed solubility: yes
Modification: -
Viscosity level (according to Höppler): 300 mPas
Form: Dustlike
Colour:Whitis
Smell:Odourless
pH-value(10g/l)at20°C:7
Changeincondition
Melting point/Melting range: Not determined
Boiling point/Boiling range: Not determined
Flash point: Not applicable
Inflammability(solid,gaseous): Product is not inflammable.
Ignition temperature: >360°C
Self-inflammability: >190°C-
Densityat20°C1.39g/cm³
Solubilityin/Miscibility with-Water:Soluble
Partition coefficient(n-octanol/water):<3logPOW
Viscosity: dynamicat20°C: 300mPas(20g/lH2O)
Other information: No further relevant information available.
Melting Point: -60°C
Flash Point: >214°F
Density: 0.935 (25°C)
Viscosity: 10cs (25°C)
Alpha Sort: Polydimethylsiloxane



FIRST AID MEASURES of TYLOSE H 300 P2:
-Description of first aid measures:
*After inhalation:
Supply fresh air.
*After skin contact:
Instantly wash with water and soap and rinse thoroughly.
*After eye contact:
Rinse opened eye for several minutes under running water.
If symptoms persist,consult a doctor.
Do not rub.
*After swallowing:
In case of persistent symptoms consult doctor.
-Information for doctor:
*Most important symptoms and effects,both acute and delayed:
No further relevant information available.
*Indication of any immediate medical attention and special treatment needed:
No further relevant information available



ACCIDENTAL RELEASE MEASURES of TYLOSE H 300 P2:
-Personal precautions, protective equipment and emergency procedures:
Wear protective clothing
Product forms slippery surface when combined with water.
-Environmental precautions:
Do not allow to enter drainage system, surface or groundwater.
-Methods and material for containment and cleaning up:
Collect mechanically.
Ensure adequate ventilation.
Dispose of the material collected according to regulations.



FIRE FIGHTING MEASURES of TYLOSE H 300 P2:
-Extinguishing media:
*Suitable extinguishing agents:
Water spray jet
Foam



EXPOSURE CONTROLS/PERSONAL PROTECTION of TYLOSE H 300 P2:
-Additional information about design of technical systems:
No further data
-Exposure controls-Personal protective equipment:
*General protective and hygienic measures:
Wash hands during breaks and at the end of the work.
*Protection of hands:
Protective gloves.
The glove material has to be impermeable and resistant to the product/the substance/the preparation.
**Material of gloves:
Rubber gloves
Not required.
*Eye protection:
Safety glasses



HANDLING and STORAGE of TYLOSE H 300 P2:
-Handling-Precautions for safe handling:
Protect against electrostatic charges.
-Conditions for safe storage,including any incompatibilities:
*Storage:
**Requirements to be met by store room sand containers:
No special requirements.
-Information about storage in one common storage facility:
Not required.
-Furtherinformationaboutstorageconditions:
This product is hygroscopic.
Store in cool, dry conditions in well sealed receptacles.



STABILITY and REACTIVITY of TYLOSE H 300 P2:
-Reactivity:
*Chemical stability:
Conditions to avoid:
No further relevant information available.
-Incompatible materials:
No further relevant information available.
-Hazardous decomposition products:
No decomposition under normal storage and handling conditions.


TYLOSE H 300 P2
Tylose H 300 P2 Tylose H 300 P2 is a water-soluble, non-ionic, highly etherified hydroxyethyl cellulose powder. Tylose H 300 P2 provides increased biostability, fast consistency development, high solution clarity and thermal stability, and low sag resitance and water demand. This grade of hydroxyethyl cellulose (HEC) is ideal for use in emulsion tile adhesives, exterior, interior, and silicone resin paints, drilling fluids, non-woven fabrics, and washing up liquids. Tylose HEC (hydroxyethyl cellulose/Tylose H-grades) are soluble in water at any temperature. Tylose HEC are nonionic cellulose ethers, which are offered as free flowing powder or in granular form. Many Tylose HEC grades have a retarded solubility which ensures a lump free solution in aqueous systems. Hydroxyethyl cellulose. Tylose H 300 P2 Provides effects like thickening, pseudoplastic properties, water retention, protective colloid effects, film forming and a high level of salt tolerance. Offers high gloss, high pigment compatibility, high thickening effect and high water retention. Exhibits moderate wet scrub resistance, anti-spattering, and pseudoplasticity. Used for paints and coatings applications like interior paints, solid paints, exterior paints, tinters, glazes, and silicon resin paints. Hydroxyethylcellulose. Tylose H 300 P2 Acts as a thickening agent. Tylose H 300 P2 is available in powder form with delayed solubility. Used in shampoo. Tylose H 300 P2 is a gelling and thickening agent derived from cellulose. It is widely used in cosmetics, cleaning solutions, and other household products.[1] Tylose H 300 P2 and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids. This process is known as hydrophilization.[2] Tylose H 300 P2 is also used extensively in the oil & gas industry as a drilling mud additive under the name HEC as well in industrial applications, paint & coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers. Tylose H 300 P2 is one of the main ingredients in the personal lubricant KY Jelly. It is also a key ingredient in the formation of big bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble. Among other similar chemicals, it is often used as slime (and gunge, in the UK), a gooey substance often used on television and in fundraising events which is poured over individuals with the aim of causing embarrassment. Tylose H 300 P2 acts as a demulcent by relieving inflammation or irritation and dryness of eyes. It acts as one of the key ingredient and viscosity-enhancing agent to prolong corneal contact time and increase intraocular drug levels. Application Tylose H 300 P2 is used as a gelling and thickening agent in the development of biostructures for the delivery of hydrophobic drugs. Tylose H 300 P2 is used in the development of polymer networks and block copolymers useful in separation technology such as capillary electrophoresis and in biofilms and coatings. Tylose H 300 P2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps. General properties Hydroxyethyl cellulose (Tylose H 300 P2) polymer is a hydroxyethyl ether of cellulose, obtained by treating cellulose with sodium hydroxide and reacting with ethylene oxide. Tylose H 300 P2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps. They are available as white free-flowing granular powders that easily dissolve in cold and hot water to give transparent solutions with varying viscosities depending on polymer concentration, type and temperature. Natrosol 250 Tylose H 300 P2 is available in 10 viscosity types, that go from low viscosity values (types L and J) ranging between 0.08 and 0.4 Pas at c = 5 wt.%, intermediate viscosity values (types E, G, K, M) ranging between 0.03 and 6.5 Pas at c = 2 wt.%, arriving to the highest viscosity values (types MH, H, HH) ranging between 0.8 and 5 Pas at c = 1 wt.% (informations are given in the producer booklet Aqualon, 1999). The molecular weight and the degree of polymerization of the Natrosol™ Tylose H 300 P2 types is directly proportional to their viscosity. Being a nonionic polymer, Natrosol™ is less sensitive to pH changes; however, pH and temperature may slight affect the hydration and dissolution time of the polymer. Effect of extent of substitution on solubility When highly polar hydroxyl groups on crystalline cellulose are substituted with hydroxyalkyl groups to manufacture HPC or Tylose H 300 P2, water solubility initially increases due to a reduction in crystallinity and hydrogen bonding between the cellulose backbone chains. However, as the amount of hydroxyalkyl substitution continues to increase, the polymer becomes increasingly hydrophobic. As shown in Fig. 7.31, the equilibrium moisture content steadily decreases as MS increases from 2.0 to 5.0 for both Tylose H 300 P2 and HPC. A similar relationship has also been demonstrated for the cloud point.43 An exception to this behavior is polymers with ionic groups in their side chains. In this case, increasing the level of highly polar substituents will increase water solubility. For example, when the DS for sodium carboxymethyl cellulose is increased from 0.7 to 1.2, the equilibrium moisture content at 50% relative humidity increases from 13% to 18%. Regenerated Tylose H 300 P2 is made by dissolving cellulose xanthate in 4–7% sodium hydroxide and contacting with aqueous sulfuric acid. These steps convert the cellulose xanthate back into cellulose, which may be spun into viscose rayon or cast into films. The fibers are used in textiles (artificial silk), tyre cords, and V belts. The films are used in packaging (Cellophane) or sausage casings. Weiner casings (70% regenerated cellulose, 12% glycerol, and 18% water) are peeled away after the meat emulsion is cooked. Hemp paper casings (23% paper, 46% regenerated cellulose, 21% glycerol, and 10% water) are used in bologna, salami, pepperoni, summer sausage, and liverwurst. Tylose H 300 P2 moieties are highly reactive, allowing a variety of esters and ethers to be manufactured. Because each anhydroglucose has three hydroxyl groups, the maximum degree of substitution (DS) is three. Purified wood pulp or cotton linters (short fibers) are the industrial sources of ‘chemical cellulose.’ Tylose H 300 P2 Usage And Synthesis Thickeners and binders Tylose H 300 P2 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +. Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid. The role of thickener in the aqueous ink is thickened. The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink. Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances. Cellulose substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Tylose H 300 P2 and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000. The above information is edited by the chemicalbook of Liu Yujie. Chemical properties This product is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water. Insoluble in common organic solvents. Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding. Different viscosity range of solution can be prepared. Having exceptionally good salt solubility to electrolyte. Uses 1. This product is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride. Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry. Glazing in ceramic industry and toothpaste binder. Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent. 2. Used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid. Also can be used for filtrate reducer of oil well cement. Cross-linking with the polyvalent metal ions into a gel. 3. As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion. Widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides. There are many uses in oil exploitation and machinery industry. 4. As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc. Production methods 1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give Tylose H 300 P2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour. Squeezed water containing soda to 1: 2.8, pulverized. Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle. Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Tylose H 300 P2 was obtained. The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging. Then washed with water, centrifugal dewatering, dryed, milled to obtain Tylose H 300 P2. Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300. 2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze. Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into. In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Tylose H 300 P2. The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Tylose H 300 P2. Description Hetastarch, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa). When infused as a 6% solution, hetastarch approximates the activity of human albumin. The larger molecular weights, however, increase its intravascular residence time as well as its plasma expansion effects relative to albumin. Hetastarch is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids. Despite these advantages, hetastarch is quite expensive and also has no oxygen-carrying capacity. Chemical Properties light yellow powder Chemical Properties Tylose H 300 P2 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder. Uses disintegrant, binder for tabletting Uses Tylose H 300 P2 is a thickener, protective colloid, binder, stabilizer, and suspending agent. It is obtained from wood pulp Copyright 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s). Editorial Review has deemed that any suppressed content does not materially affect the overall learning experience. Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require it. or chemical cotton by treatment with an alkali. Definition A starch derivative containing 90% amylopectin. Production Methods A purified form of cellulose is reacted with sodium hydroxide to produce a swollen alkali cellulose, which is chemically more reactive than untreated cellulose. The alkali cellulose is then reacted with ethylene oxide to produce a series of Tylose H 300 P2 ethers. The manner in which ethylene oxide is added to cellulose can be described by two terms, the degree of substitution (DS) and the molar substitution (MS). The DS designates the average number of hydroxyl positions on the anhydroglucose unit that have been reacted with ethylene oxide. Since each anhydroglucose unit of the cellulose molecule has three hydroxyl groups, the maximum value for DS is 3. MS is defined as the average number of ethylene oxide molecules that have reacted with each anhydroglucose unit. Once a hydroxyethyl group is attached to each unit, it can further react with additional groups in an end-to-end formation. This reaction can continue and there is no theoretical limit for MS. Brand name Hespan (DuPont Merck) . Pharmaceutical Applications Tylose H 300 P2 is a nonionic, water-soluble polymer widely used in pharmaceutical formulations. It is primarily used as a thickening agent in ophthalmic and topical formulations, although it is also used as a binder and film-coating agent for tablets.It is present in lubricant preparations for dry eye, contact lens care, and dry mouth. The concentration of Tylose H 300 P2 used in a formulation is dependent upon the solvent and the molecular weight of the grade. Tylose H 300 P2 is also widely used in cosmetics. Safety Tylose H 300 P2 is primarily used in ophthalmic and topical pharmaceutical formulations. It is generally regarded as an essentially nontoxic and nonirritant material. Acute and subacute oral toxicity studies in rats have shown no toxic effects attributable to Tylose H 300 P2 consumption, the Tylose H 300 P2 being neither absorbed nor hydrolyzed in the rat gastrointestinal tract. However, although used in oral pharmaceutical formulations, Tylose H 300 P2 has not been approved for direct use in food products. Glyoxal-treated Tylose H 300 P2 is not recommended for use in oral pharmaceutical formulations or topical preparations that may be used on mucous membranes. Tylose H 300 P2 is also not recommended for use in parenteral products. storage Tylose H 300 P2 powder is a stable though hygroscopic material. Aqueous solutions of Tylose H 300 P2 are relatively stable at pH 2–12 with the viscosity of solutions being largely unaffected. However, solutions are less stable below pH 5 owing to hydrolysis. At high pH, oxidation may occur. Increasing the temperature reduces the viscosity of aqueous Tylose H 300 P2 solutions. However, on cooling, the original viscosity is restored. Solutions may be subjected to freeze–thawing, high-temperature storage, or boiling without precipitation or gelation occurring. Tylose H 300 P2 is subject to enzymatic degradation, with consequent loss in viscosity of its solutions. Enzymes that catalyze this degradation are produced by many bacteria and fungi present in the environment. For prolonged storage, an antimicrobial preservative should therefore be added to aqueous solutions. Aqueous solutions of Tylose H 300 P2 may also be sterilized by autoclaving. Tylose H 300 P2 powder should be stored in a well-closed container, in a cool, dry place. Incompatibilities Tylose H 300 P2 is insoluble in most organic solvents. It is incompatible with zein and partially compatible with the following water-soluble compounds: casein; gelatin; methylcellulose; polyvinyl alcohol, and starch. Tylose H 300 P2 can be used with a wide variety of watersoluble antimicrobial preservatives. However, sodium pentachlorophenate produces an immediate increase in viscosity when added to Tylose H 300 P2 solutions. Tylose H 300 P2 has good tolerance for dissolved electrolytes, although it may be salted out of solution when mixed with certain salt solutions. For example, the following salt solutions will precipitate a 10% w/v solution of Cellosize WP-09 and a 2% w/v solution of Cellosize WP-4400: sodium carbonate 50% and saturated solutions of aluminum sulfate; ammonium sulfate; chromic sulfate; disodium phosphate; magnesium sulfate; potassium ferrocyanide; sodium sulfate; sodium sulfite; sodium thiosulfate; and zinc sulfate. Natrosol is soluble in most 10% salt solutions, excluding sodium carbonate and sodium sulfate, and many 50% salt solutions with the exception of the following: aluminum sulfate; ammonium sulfate; diammonium phosphate; disodium phosphate; ferric chloride; magnesium sulfate; potassium ferrocyanide; sodium metaborate; sodium nitrate; sodium sulfite; trisodium phosphate; and zinc sulfate. Natrosol 150 is generally more tolerant of dissolved salts than is Natrosol 250. Tylose H 300 P2 is also incompatible with certain fluorescent dyes or optical brighteners, and certain quaternary disinfectants which will increase the viscosity of aqueous solutions. Regulatory Status Included in the FDA Inactive Ingredients Database (ophthalmic preparations; oral syrups and tablets; otic and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients. Tylose H 300 P2 is not currently approved for use in food products in Europe or the USA, although it is permitted for use in indirect applications such as packaging. This restriction is due to the high levels of ethylene glycol residues that are formed during the manufacturing process. Description Tylose H 300 P2 is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as artificial tear solutions and adjunct agent in topical drug formulations to facilitate the delivery of drugs with hydrophobic character. Pharmacodynamics Tylose H 300 P2 acts as a demulcent by relieving inflammation or irritation and dryness of eyes. It acts as one of the key ingredient and viscosity-enhancing agent to prolong corneal contact time and increase intraocular drug levels 4. Mechanism of action Interacts with the solid surface through hydrogen bonding to thicken and prolong the formation time of a water-retaining film. Tylose H 300 P2 acts as a drug carrier or microsphere to entrap other drug molecules and form a viscous gel-like dispersion, enabling drug diffusion across biological membranes 3. Indication For alleviating surface irritation in topical ocular administrations, such as artificial tear solutions. Tylose H 300 P2 is also found in topical formulations to aid in more efficient drug diffusion across the membranes. Toxicity May cause chemical pneumonitis in case of inhalation and skin irritation. Animal data suggests potential alteration in female fertility. Tyloses are outgrowths/extragrouth on parenchyma cells of xylem vessels of secondary heartwood. When the plant is stressed by drought or infection, tyloses will fall from the sides of the cells and "dam" up the vascular tissue to prevent further damage to the plant. Tyloses can aid in the process of making sapwood into heartwood in some hardwood trees, especially in trees with larger vessels.[1] These blockages can be used in addition to gum plugs as soon as vessels become filled with air bubbles, and they help to form a stronger heartwood by slowing the progress of rot. Tylose H 300 P2 is cellulose in which both ethyl and hydroxyethyl groups are attached to the anhydroglucose units by ether linkages. Tylose H 300 P2 is prepared from cellulose by treatment with alkali, ethylene oxide and ethyl chloride. The article of commerce may be specified further by the viscosity of its aqueous solutions. Advantages and drawbacks Tylose H 300 P2 solutions exhibit several advantages for analogue modeling. The viscosity of the solutions can be easily varied by changing the concentration of the polymer without affecting the density (Boutelier et al., 2016). Moreover, solutions can be seeded with reflective or fluorescent particles and thermochromics liquid crystals (TLC) (Limare et al., 2013, 2015; Fourel et al., 2017) that allow the modelers to track the flows by means of the particle imaging velocimetry (PIV) and/or to quantify the temperature field, respectively. Such particles can be considered neutrally buoyant with respect to water, and hence, to Tylose H 300 P2 solutions. An other advantage of working with Tylose H 300 P2 solutions is that they do not gel or precipitate when temperature is increased, even up to the boiling point of water (Aqualon, 1999). Two types of can be blended to obtain intermediate values of η. Being η an exponential function of c and degree of polymerization, the resulting η is not an arithmetic mean. Hence, blending charts, available from Aqualon, should be followed (Aqualon, 1999). Tylose H 300 P2 is also compatible with a large range of water-soluble materials, that is, water-soluble polymers and natural gums, such as guar gum or xanthan gum (Aqualon, 1999). For instance, can be blended with an anionic polymer such as carboxymethylcellulose to obtain very high η, clear solutions. However, Tylose H 300 P2 shows few limitations. polymers are hygroscopic and absorb moisture from the atmosphere. In order to keep the original moisture content, the powders should be stored in sealed containers at dry atmosphere. Moreover, despite the ease solubility of in water, particles tend to agglomerate as they are in contact with water. Manufacturer provides few procedures in order to obtain the most efficient solution preparation and created a surface-treated grade of that does not lump when wetted (Aqualon, 1999). solutions can be exposed to biological attack, so producers suggest to add preservative when it is planned to store them for long time. Hydroxyethyl cellulose Hydroxyethyl cellulose (Tylose H 300 P2) is a cellulose-derived thickening and the gelling agent used in capsules containing hydrophobic drugs in order to improve dissolution of drugs within GI fluids in a method known as the hydrophilization method. This nonionic and water-soluble polymer is also used in cosmetics, cleaning solutions, and other household products. It will fabricate crystal-clear gel products and thicken the aqueous phase of cosmetic emulsions. Their tendency to lump or agglomerate, when first wetted with water, is a disadvantage associated with Tylose H 300 P2s and other water-soluble thickeners. The R-grade of Tylose H 300 P2s facilitates solution preparation without lumping when wetted with water, thus increasing dissolution and total processing times (Joshi and Petereit, 2013). Chowdary et al. established a formulation of film-coated bilayer paliperidone tablet and validated it against in vitro performance results of Invega, a tri-layered innovator sample. Core formulations formed by diverse ratio polyox were optimized and coatings were optimized for enterically coating cellulose acetate and subcoating of Tylose H 300 P2. They investigated influencing factors such as different ingredients in the coating solution and compositions of the core tablet. They even optimized the formulation and its process by comparing different in vitro release behaviors of paliperidone (Chowdary and Napoleon, 2017). Effect of extent of substitution on solubility When highly polar hydroxyl groups on crystalline cellulose are substituted with hydroxyalkyl groups to manufacture HPC or Tylose H 300 P2, water solubility initially increases due to a reduction in crystallinity and hydrogen bonding between the cellulose backbone chains. However, as the amount of hydroxyalkyl substitution continues to increase, the polymer becomes increasingly hydrophobic. As shown in Fig. 7.31, the equilibrium moisture content steadily decreases as MS increases from 2.0 to 5.0 for both Tylose H 300 P2 and HPC. A similar relationship has also been demonstrated for the cloud point.43 An exception to this behavior is polymers with ionic groups in their side chains. In this case, increasing the level of highly polar substituents will increase water solubility. For example, when the DS for sodium carboxymethyl cellulose is increased from 0.7 to 1.2, the equilibrium moisture content at 50% relative humidity increases from 13% to 18%. Tylose H 300 P2 Chemical Properties,Uses,Production Thickeners and binders Tylose H 300 P2 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +. Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid. The role of thickener in the aqueous ink is thickened. The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink. Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances. Cellulose substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Tylose H 300 P2 and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000. The above information is edited by the chemicalbook of Liu Yujie. Chemical properties This product is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water. Insoluble in common organic solvents. Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding. Different viscosity range of solution can be prepared. Having exceptionally good salt solubility to electrolyte. Uses 1. This product is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride. Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry. Glazing in ceramic industry and toothpaste binder. Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent. 2. Used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid. Also can be used for filtrate reducer of oil well cement. Cross-linking with the polyvalent metal ions into a gel. 3. As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion. Widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides. There are many uses in oil exploitation and machinery industry. 4. As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc. Production methods 1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give Tylose H 300 P2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour. Squeezed water containing soda to 1: 2.8, pulverized. Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle. Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Tylose H 300 P2 was obtained. The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging. Then washed with water, centrifugal dewatering, dryed, milled to obtain Tylose H 300 P2. Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300. 2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze. Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into. In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Tylose H 300 P2. The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Tylose H 300 P2. Description Hetastarch, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa). When infused as a 6% solution, hetastarch approximates the activity of human albumin. The larger molecular weights, however, increase its intravascular residence time as well as its plasma expansion effects relative to albumin. Hetastarch is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids. Despite these advantages, hetastarch is quite expensive and also has no oxygen-carrying capacity. Chemical Properties light yellow powder Chemical Properties Tylose H 300 P2 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder. Uses disintegrant, binder for tabletting Uses Tylose H 300 P2 is a thickener, protective colloid, binder, stabilizer, and suspending agent. It is obtained from wood pulp Copyright 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s). Editorial Review has deemed that any suppressed content does not materially affect the overall learning experience. Cengage
TYLOSE H 4000 NG4
Hydroxyethyl cellulose; 4070 NG4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;thickener ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE H 4070 NG4
Hydroxyethyl cellulose; H 6000 YP2; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;thickener ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE H 4070 NG4
Acts as a thickening agent.
TYLOSE H 4070 NG4 is available in granular form with non-delayed solubility.
TYLOSE H 4070 NG4 used in permanent-wave preparations, hair colors, toothpaste, body lotion, sun care, roll-on deo and mascara.

CAS: 9004-62-0
MF: C29H52O21
EINECS: 618-387-5

TYLOSE H 4070 NG4, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa).
When infused as a 6% solution, TYLOSE H 4070 NG4 approximates the activity of human albumin.
The larger molecular weights, however, increase its intravascular residence time as well as TYLOSE H 4070 NG4's plasma expansion effects relative to albumin.
Hetastarch is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids.
Despite these advantages, TYLOSE H 4070 NG4 is quite expensive and also has no oxygen-carrying capacity.

TYLOSE H 4070 NG4 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +.
Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid.
The role of thickener in the aqueous ink is thickened.

The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink.
Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances.
TYLOSE H 4070 NG4 substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Hydroxyethyl cellulose and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000.
A starch derivative containing 90% amylopectin.
Non-ionic water soluble polymer.
Aqueous solutions are pseudoplastic.
Readily disperses without lumping.

TYLOSE H 4070 NG4 is a non-ionic, water-soluble cellulose derivative produced by introduction of ethylene oxide groups to the hydroxyl groups of the cellulose backbone.
TYLOSE H 4070 NG4 is useful as a water thickener, rheological control additive, protective colloid, binder, stabilizer, suspending agent and film former.
TYLOSE H 4070 NG4 is used in many industrial applications including latex paints, emulsion polymerization, petroleum, paper, pharmaceuticals, cosmetics and many other applications.

TYLOSE H 4070 NG4 Chemical Properties
Melting point: 288-290 °C (dec.)
Density: 0.75 g/mL at 25 °C(lit.)
Storage temp.: 2-8°C
Solubility H2O: ≤5 wt. % at 20 °C
Form: powder
Color: Light brown powder
Odor: Odorless
PH: pH(20g/l,25℃) : 5.0~8.0
Water Solubility: almost transparency
Merck: 14,4673
Stability: Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides
InChI: InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3
InChIKey: CWSZBVAUYPTXTG-UHFFFAOYSA-N
CAS DataBase Reference: 9004-62-0(CAS DataBase Reference)
EPA Substance Registry System: TYLOSE H 4070 NG4 (9004-62-0)

TYLOSE H 4070 NG4 is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water.
Insoluble in common organic solvents.
Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding.
Different viscosity range of solution can be prepared.
Having exceptionally good salt solubility to electrolyte.
TYLOSE H 4070 NG4 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder.
TYLOSE H 4070 NG4 is soluble in hot or cold water, and does not precipitate at high temperature or boiling, so it has a wide range of solubility and viscosity characteristics, as well as non-thermal gelling properties.

TYLOSE H 4070 NG4 is a non-ionic polymer material , can coexist with a wide range of other water-soluble polymers, surfactants, and salts, and is an excellent colloidal thickener for high-concentration dielectric solutions.
The water retention capacity of TYLOSE H 4070 NG4 is twice that of methyl cellulose, and it has better flow regulation; the dispersing ability of hydroxyethyl cellulose is comparable to that of methyl cellulose and hydroxypropyl methyl cellulose.
The specific dispersing ability is the worst, but the protective colloid ability is the strongest.

Uses
1. TYLOSE H 4070 NG4 is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride.
Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry.
Glazing in ceramic industry and toothpaste binder.
Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent.
2. Used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid.
Also can be used for filtrate reducer of oil well cement.
Cross-linking with the polyvalent metal ions into a gel.
3. As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion.
Widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides.
There are many uses in oil exploitation and machinery industry.
4. As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc.
Thickener, protective colloid, binder, stabilizer and suspending agent.

TYLOSE H 4070 NG4 is a thickener, protective colloid, binder, stabilizer, and suspending agent.
TYLOSE H 4070 NG4 is obtained from wood pulp Copyright 2014 Cengage Learning.
May not be copied, scanned, or duplicated, in whole or in part.
Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s).
Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require TYLOSE H 4070 NG4 or chemical cotton by treatment with an alkali.

TYLOSE H 4070 NG4 is a nonionic, water-soluble polymer widely used in pharmaceutical formulations.
TYLOSE H 4070 NG4 is primarily used as a thickening agent in ophthalmic and topical formulations, although it is also used as a binder and film-coating agent for tablets.
TYLOSE H 4070 NG4 is present in lubricant preparations for dry eye, contact lens care, and dry mouth.
The concentration of TYLOSE H 4070 NG4 used in a formulation is dependent upon the solvent and the molecular weight of the grade.
TYLOSE H 4070 NG4 is also widely used in cosmetics.

Production methods
1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give TYLOSE H 4070 NG4.
The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour.
Squeezed water containing soda to 1: 2.8, pulverized.
Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle.
Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of TYLOSE H 4070 NG4 was obtained.
The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging.
Then washed with water, centrifugal dewatering, dryed, milled to obtain TYLOSE H 4070 NG4.
Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300.

2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze.
Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle, Precooled the liquid ethylene oxide was pressed into.
In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Hydroxyethyl cellulose.
The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt TYLOSE H 4070 NG4.

Production Methods
A purified form of cellulose is reacted with sodium hydroxide to produce a swollen alkali cellulose, which is chemically more reactive than untreated cellulose.
The alkali cellulose is then reacted with ethylene oxide to produce a series of TYLOSE H 4070 NG4 ethers.
The manner in which ethylene oxide is added to cellulose can be described by two terms, the degree of substitution (DS) and the molar substitution (MS).
The DS designates the average number of hydroxyl positions on the anhydroglucose unit that have been reacted with ethylene oxide.
Since each anhydroglucose unit of the cellulose molecule has three hydroxyl groups, the maximum value for DS is 3.

MS is defined as the average number of ethylene oxide molecules that have reacted with each anhydroglucose unit.
Once a hydroxyethyl group is attached to each unit, TYLOSE H 4070 NG4 can further react with additional groups in an end-to-end formation.
This reaction can continue and there is no theoretical limit for MS.
TYLOSE H 4070 NG4 is prepared from alkali cellulose and ethylene oxide.
TYLOSE H 4070 NG4 may be noted that the hydroxyethyl group itself can react with ethylene oxide so that side-chains of varying length may be present in the product.
Commercial materials generally contain between 1.4 and 2.0 ethylene oxide residues per glucose residue and have a degree of substitution of about 0.8-1.0.

Toxicology
Considered to be non toxic.
Use as a food additive indicates good tolerance of small amounts, but excessive amounts or overuse may bring irritant and /or harmful effects.
Polysaccharides are not substantially absorbed from the gastrointestinal tract but may produce a laxative effect.

Incompatibilities
TYLOSE H 4070 NG4 is insoluble in most organic solvents.
TYLOSE H 4070 NG4 is incompatible with zein and partially compatible with the following water-soluble compounds: casein; gelatin; methylcellulose; polyvinyl alcohol, and starch.
TYLOSE H 4070 NG4 can be used with a wide variety of watersoluble antimicrobial preservatives.
However, sodium pentachlorophenate produces an immediate increase in viscosity when added to TYLOSE H 4070 NG4 solutions.
TYLOSE H 4070 NG4 has good tolerance for dissolved electrolytes, although it may be salted out of solution when mixed with certain salt solutions.

For example, the following salt solutions will precipitate a 10% w/v solution of Cellosize WP-09 and a 2% w/v solution of Cellosize WP-4400: sodium carbonate 50% and saturated solutions of aluminum sulfate; ammonium sulfate; chromic sulfate; disodium phosphate; magnesium sulfate; potassium ferrocyanide; sodium sulfate; sodium sulfite; sodium thiosulfate; and zinc sulfate.
Natrosol is soluble in most 10% salt solutions, excluding sodium carbonate and sodium sulfate, and many 50% salt solutions with the exception of the following: aluminum sulfate; ammonium sulfate; diammonium phosphate; disodium phosphate; ferric chloride; magnesium sulfate; potassium ferrocyanide; sodium metaborate; sodium nitrate; sodium sulfite; trisodium phosphate; and zinc sulfate.
TYLOSE H 4070 NG4 is generally more tolerant of dissolved salts than is Natrosol 250.
TYLOSE H 4070 NG4 is also incompatible with certain fluorescent dyes or optical brighteners, and certain quaternary disinfectants which will increase the viscosity of aqueous solutions.

Synonyms
Hydroxyethyl cellulose
9004-62-0
Hespan
Cellulose, 2-hydroxyethyl ether
2-Hydroxyethyl cellulose
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
Cellulosize
Cellosize
Natrosol
Cellosize QP
Cellosize WP
Tylose H series
Natrosol LR
Tylose P
Cellosize QP3
OETs
Tylose P-X
Tylose PS-X
Cellosize UT 40
Cellosize WP 09
Tylose P-Z series
Glutofix 600
Natrosol 150L
Natrosol 180HH
Natrosol 180L
Natrosol 240JR
Natrosol 250
Natrosol 250G
Natrosol 250H
Natrosol 250HHP
Natrosol 250HHR
Natrosol 250HR
Natrosol 250HX
Natrosol 250L
Natrosol 250M
Natrosol 250MH
Natrosol 300H
Hercules N 100
Hydroxyethyl-cellulose
Natrosol 250H4R
Cellosize WP 300
Tylose H 20
Fuji hec-BL 20
Caswell No. 487
Natrosol 250 HHR
Cellosize WP 300H
Cellosize WP 400H
Unicel QP 100MH
Tylose H 300
Cellosize QP 1500
Cellosize QP 4400
Cellosize WP 4400
Cellosize WPO 9H17
Unicel QP 300 H
Cellosize 4400H16
Cellosize QP 30000
UNII-12VCE9HR9E
UNII-7Q6P4JN1QT
UNII-B24JYI97VR
UNII-R33S7TK2EP
UNII-X70SE62ZAR
UNII-ZYD53NBL45
Hydroxyethyl cellulose ether
Hydroxyethyl ether cellulose
Hec-Al 5000
Unicel QP 52000 H
Hydroxyethyl cellulose [NF]
UNII-6OX6A5C7B6
UNII-S38J6RZN16
Walocel HT 6.000 PFV
UNII-273FM27VK1
UNII-2Q40985DRM
UNII-I2N4ZF9233
UNII-M825OX60H9
Cellulose 2-hydroxyethyl ether
HSDB 578
SCHEMBL23306563
UNII-8136Y38GY5
UNII-L605B5892V
Cellulose, 2- hydroxyethyl ether
Cellulose, ethylene oxide-grafted
DTXSID60873934
AH 15
BL 15
EPA Pesticide Chemical Code 046201
LS-146657
FT-0627136
J 164
H11622
2-Hydroxyethyl cellulose; Cellulose hydroxyethyl ether
2-O-(2-Hydroxyethyl)-4-O-methylhexopyranosyl-(1->4)-[4-O-methylhexopyranosyl-(1->6)]hexopyranosyl-(1->5)-2,6-anhydro-1-deoxyheptitol
TYLOSE H 6000 YP2
Hydroxyethyl cellulose; HS 100,000 YP2; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;thickener ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE HS 100,000 YP2
Hydroxyethyl Cellulose,2-hydroxyethylcelluloseether;ah15;aw15(polysaccharide);aw15[polysaccharide];bl15;cellosize;Hydroxyethyl cellulose - Viscosity 1500 ~ 2500;The blood coHydroxyethyl cellulose etherngeals the appearance board CAS: 9004-62-0 CAS-No. : 9004-62-0
TYLOSE HS 100000 YP2
Tylose HS 100000 YP2 is a gelling and thickening agent derived from cellulose.
Tylose HS 100000 YP2 is white or light yellowish powder.
Tylose HS 100000 YP2 is soluble in cold or hot water to give clarified solution.


CAS Number: 9004-62-0
EC number: 217-576-6


Tylose HS 100000 YP2 is a nonionic, water-soluble polymer.
Tylose HS 100000 YP2 is odorless, tasteless, and non-toxic in the shape of white to off-white powders or granules.
Tylose HS 100000 YP2 is a hydroxyethyl cellulose powder recommended for use in interior and exterior paints.


Tylose HS 100000 YP2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Tylose HS 100000 YP2 is also the most efficient grade of non-ionic thickener available from the manufacturer.
Hydration of the R-grade particles has been inhibited.


Tylose HS 100000 YP2 is natural colloids derived from natural fiber.
Tylose HS 100000 YP2 is a water soluble, non-ionic, highly esterified hydroxyethyl cellulose powder.
Tylose HS 100000 YP2 can be dissolved in water to form a transparent viscous solution.


Tylose HS 100000 YP2's nature's most abundant biopolymer in plants, wood, and cotton cell walls.
The high-purity cosmetic grade of Tylose HS 100000 YP2 we offer is an R-grade, designed to be added to water without lumping, and thus greatly facilitating solution preparation.


This nonionic, water soluble polymer, Tylose HS 100000 YP2, offers efficient and cost-effective options for making crystal clear gel products.
Tylose HS 100000 YP2 has thickening, adhesion, dispersion, emulsification, film-formation, suspension, absorption, surface activity, salt tolerance, water retention, providing protective colloids and other properties.


Tylose HS 100000 YP2 is nonionic cellulose ether and its solution are more tolerant to the presence of cations,anions and organic solvents.
Tylose HS 100000 YP2 is soluble in cold or hot water to give clarified solution.
Tylose HS 100000 YP2 is natural colloids derived from natural fiber.


Tylose HS 100000 YP2 exhibits high compatibility with other raw materials such as surfactant.
Tylose HS 100000 YP2 is bio-degradable,non-toxic and environmental friendly natural product.
Tylose HS 100000 YP2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.


Tylose HS 100000 YP2 consists of two components: cellulose and hydroxyethyl side chain.
Tylose HS 100000 YP2 acts as a thickening and stabilizing agent.
Higher pH and higher temperatures DECREASE hydration time, but the higher pH and temperature adjustments too quickly may result in lumping.


Tylose HS 100000 YP2 is a gelling and thickening agent derived from cellulose.
Tylose HS 100000 YP2 is a non-ionic cellulose ether made through a series of chemical processes, with the natural polymer celluloses as raw materials.
Tylose HS 100000 YP2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.


So, Tylose HS 100000 YP2 is recommended that it be added to room temperature water with a neutral pH.
Once hydrated, Tylose HS 100000 YP2 can be heated and the pH can be adjusted as may be needed.
Tylose HS 100000 YP2 is a white, odorless, tasteless, non-toxic, which is often used as a thickener for methyl hydroxyethyl cellulose or hydroxyethyl cellulose grades in industry agent.


Tylose HS 100000 YP2 exhibits high compatibility with other raw materials such as surfactant.
Tylose HS 100000 YP2 exhibits high compatibility with other raw materials such as surfactant.
It's recommended that the Tylose HS 100000 YP2 be added to room temperature water, with a neutral pH.


Tylose HS 100000 YP2 is a non-ionic, water-soluble polymer derived from cellulose through a series of chemical and physical processes.
Tylose HS 100000 YP2 can be heated and the pH can be adjusted (typically using TEA) as needed.
(The inhibition period, from the initial wetting to the start of dissolution, hydration time, may vary from 5-25 min)


Tylose HS 100000 YP2 is bio-degradable,non-toxic and environmental friendly natural product.
Tylose HS 100000 YP2 is a a non-ionic, water-soluble polymer efficient thickening agent and suspending agent.
Tylose HS 100000 YP2 acts as a thickening and stabilizing agent.


Tylose HS 100000 YP2 forms a non-ionic gel without the effect of electrolyte, suitable for formulations containing electrolyte.
When pH in solution is within 2 to 12, the solution is quite stable.
Tylose HS 100000 YP2 is easily dissolved in cold or hot water to give crystal-clear solutions of varying viscosities.


Since Tylose HS 100000 YP2 group is nonionic one in water solution, it won't be reacted with other anions or cations and insensitive to the salts.
But Tylose HS 100000 YP2 molecule is capable of generating esterification, etherification and acetal reaction, so Tylose HS 100000 YP2 is possible to make it insoluble in water or improve its properties.


Tylose HS 100000 YP2 provides enhanced biostability, very high thickening and water retention, moderate foam stabilization and high solution clarity, gloss appearance, pigment compatibility and pseudoplasticity.
Hydroxethyl Cellulose (HEC) has an exceptional skin feel and is the perfect ingredient to make crystal clear serums for water soluble active ingredients.


Tylose HS 100000 YP2 is a non-ionic, water soluble polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Tylose HS 100000 YP2also has good film-forming ability and surface activity.
Tylose HS 100000 YP2 is a nonionic, water-soluble polymer.


Tylose HS 100000 YP2 is produced by treating reacting alkali-cellulose with ethylene oxide.
Tylose HS 100000 YP2 has many properties.
Tylose HS 100000 YP2's beneficial to various construction projects.


Tylose HS 100000 YP2 is nonionic cellulose ether and its solution are more tolerant to the presence of cations,anions and organic solvents.
Tylose HS 100000 YP2 is derived from cellulose.
Tylose HS 100000 YP2 is a white, free-flowing granular powder and is made by reacting ethylene oxide with alkali-cellulose.


Recommended Percentages of Tylose HS 100000 YP2:
For Building water phase Viscosity/Stability: 0.1%- 0.5%
For high viscosity crystal clear gel: 1.0%-3.0%


Tylose HS 100000 YP2 features good water retention and an excellent thickening effect.
Tylose HS 100000 YP2 is a line of nonionic, water-soluble, cellulose based polymers from Dow.
When the particles are added to water, they disperse without lumping, and following a predetermined delay, begin to dissolve.


This process permits the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.
The inhibition period, from the initial wetting to the start of dissolution, is referred to as the hydration time.


Hydration time is affected by several factors- pH and temperature of the solution, and concentration level of the Tylose HS 100000 YP2, and the presence of alkalis like TEA, Sodium hydroxide (pH) solution.
Tylose HS 100000 YP2 is a white to light yellowish, oderless and tastless powder, readily soluble in hot or cold water to form a viscous gel solution.


Tylose HS 100000 YP2 is like water retention, thickening, suspension, anti-microbial, high salt tolerance, and ion/PH insensitivity.
Tylose HS 100000 YP2 is an excellent thickening agent for cosmetic and personal care formulations.
Tylose HS 100000 YP2 will produce crystal clear gel products and thicken the aqueous phase of cosmetic emulsions.


Tylose HS 100000 YP2 is a water-soluble synthetic polymer derived from cellulose in which ethylene oxide groups have been added to the hydroxyl groups.
Tylose HS 100000 YP2 is white or light yellowish powder.
Tylose HS 100000 YP2 can be also be used to efficiently thicken shampoos, body washes and shower gels.
One of the problems normally associated with this and other water-soluble thickeners is the tendency of the particles to agglomerate or lump when first wetted with water.



USES and APPLICATIONS of TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride.
Solutions of high molecular weight Tylose HS 100000 YP2, however, behave in a non-Newtonian manner and will have a pseudo-plastic rheology.
In pharmaceuticals, cellulose has been used as an adsorbent, glidant, drug solvent, and suspending agent.


Tylose HS 100000 YP2 is one of the main components of the personal lubricant brand known as K-Y Jelly.
This pseudoplasticity makes high viscosity grades of Tylose HS 100000 YP2 an ideal thickener for latex paint applications where the paint must stay on the brush, yet flow out easily upon brushing.
paint.


One of the most important applications of Tylose HS 100000 YP2 and HMHEC are waterborne architectual coatings.
They are either used alone or in combination with other thickeners.
Infact, Tylose HS 100000 YP2 is the most widely used thickener in exterior latex paints because it is compatible with many coating ingredients such as pigments, surfactants, emulsifiers, preservatives, and binders.


Tylose HS 100000 YP2 is used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier.
Tylose HS 100000 YP2 is also used for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry.


In addition to its useful nature as a thickening agent, Tylose HS 100000 YP2 also provides the benefits of a suspension aid, binder, emulsifier, film former, emulsion stabilizer, dispersant, water retention aid, and protective colloid.
Tylose HS 100000 YP2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps.


Tylose HS 100000 YP2 can also be found in household cleaning products.
Tylose HS 100000 YP2 is used glazing in ceramic industry and toothpaste binder.
Tylose HS 100000 YP2 can be used in building materials, paints industry, petrochemicals, synthetic resin, ceramic industry, pharmaceutical, food, textile, agriculture, cosmetics, tobacco, ink, papermaking and other industries.


In medicine field, Tylose HS 100000 YP2 and methyl cellulose(MHEC) are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.
Tylose HS 100000 YP2 is a cellulose ether that is primarily used as a thickener for water-based paint, ink, and adhesive formulations.


Tylose HS 100000 YP2 is also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent.
The applications for Tylose HS 100000 YP2 range but in the industrial space it is primarily used for general thickening applications in latex paints, household cleaners and tape-joint compounds.


Tylose HS 100000 YP2 powders consolidate many advantages and contribute to the construction field.
Tylose HS 100000 YP2 is used to thicken shampoos, gels, body washes, and add body and after feel to bubble baths, body care products, lotions and creams.
Tylose HS 100000 YP2 is used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid.


Tylose HS 100000 YP2 finds applications as a binder, film former, rheology modifer (thickener), adhesion promoter, dispersion stabilizer, extender and slumping reducer in numerous products including paints, inks, adhesives, cosmetics, personal care products, textiles, cements, ceramics and paper products.
Tylose HS 100000 YP2 also can be used for filtrate reducer of oil well cement.


Tylose HS 100000 YP2 acts as a thickening and stabilizing agent.
Tylose HS 100000 YP2 is used to obtain the optimum hydration time to prevent agglomeration caused by accelerators greater than the optimal dissolution rate.
Tylose HS 100000 YP2 is used cross-linking with the polyvalent metal ions into a gel.


Tylose HS 100000 YP2 is characterized by the formation of viscous gels in water, useful for making paints, adhesives for construction, as well as in the paper and oil industry, among others.
Tylose HS 100000 YP2 is used in paint&coating formulations to increase the viscosity of the paint and to improve its flow and leveling properties.


Tylose HS 100000 YP2 is used as surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion.
Tylose HS 100000 YP2 is used as adhesives, bonding aids, filling cement admixtures


Tylose HS 100000 YP2 scientific research team specifically for the texture paint, latex paint development of a product, product thickening suspension effect is good, high water retention rate, a small amount of addition, low product unit price can reduce the production cost.
Tylose HS 100000 YP2 is used as a thickener,binder, stabilizer,film forming, protective colloids and suspending agent.


Tylose HS 100000 YP2 is used as a thickener for a series of organic solvents.
Tylose HS 100000 YP2 polymer is a hydroxyethyl ether of cellulose, obtained by treating cellulose with sodium hydroxide and reacting with ethylene oxide.
Tylose HS 100000 YP2 is widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides.


Tylose HS 100000 YP2 is used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs
Tylose HS 100000 YP2 is used as a non-ionic cellulose thickener, usually to enhance viscosity, increase concentration by absorbing water, increase viscosity, increase stability, increase degradability, and increase gloss.


Tylose HS 100000 YP2 can also be used to make crystal clear, water soluble hair styling gels.
In addition, Hydroxethyl Cellulose (HEC) offers excellent functionality when used in the water phase of emulsions to build viscosity and stability.
However, Hydroxethyl Cellulose (HEC) is not an emulsifier and will not emulsify oils into water.


Tylose HS 100000 YP2 is suitable for latex paint, oil drilling, adhesives, and personal care.
Tylose HS 100000 YP2 is mainly used in water-based products.
Tylose HS 100000 YP2 is used in rinses, hair conditioner, hair gel and shaving products.


There are many uses in oil exploitation and machinery industry.
Tylose HS 100000 YP2 is a non-ionic soluble cellulose ether, soluble in both cold and hot water, thickening, suspension, adhesion, emulsification, film formation, water retention, protective colloids and other properties, used in coatings.


Tylose HS 100000 YP2 is used as surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc.
Tylose HS 100000 YP2 acts as a non-ionic thickening agent.


Tylose HS 100000 YP2 is easy to use and provides exceptional skin feel, viscosity and stability.
Tylose HS 100000 YP2 is used in rinses, hair conditioner, hair gel and shaving products.
In the production of paper, in the production of pet bedding for the production of aqueous polymer emulsions based on ethylene-derived compounds, in the production of pharmaceuticals for the production of various creams and lotions, in the production of toothpaste, in the plastics industry.


Tylose HS 100000 YP2 enhances the viscosity of drilling fluid.
Tylose HS 100000 YP2 is used in broad range of applications includes cosmetic & personnel care,Paint & coating, oilfield, construction, etc.,as a thickener,binder,stabilizer,film forming, protective colloids and suspending agent.


Tylose HS 100000 YP2 is used in various formulations such as film formulations, emulsifiers, flow regulators, and anti-mildew.
Tylose HS 100000 YP2 is recommended as thickening agent in water-based.
Tylose HS 100000 YP2 provides excellent thickening efficiency, color development, open time, and superior resistance to biodegradation.


Tylose HS 100000 YP2 also play a role in the emulsion, dispersion, stability and water retention.
Tylose HS 100000 YP2 has uses in the cosmetics and personal care industries as a gelling and thickening agent.
Tylose HS 100000 YP2 can be one of the main ingredients in water-based personal lubricants.


Tylose HS 100000 YP2 is widely used in cosmetics, cleaning solutions, and other household products.
Tylose HS 100000 YP2 is commonly used in the production of water-based resins, the production of interior paints, the adhesive industry, the polymerization of vinyl acetate, the copolymer lactate with vinyl acrylic acid, the hydraulic fracturing process, the production of nonwovens and detergents, cosmetics, Layering of tiles.


Tylose HS 100000 YP2 is a hydroxyethyl cellulose powder recommended for use in interior and exterior paints.
Tylose HS 100000 YP2 is used as adhesives, bonding aids, filling cement admixtures.
Tylose HS 100000 YP2 easily disperses into room temperature in water without clumping or forming fish-eyes.


Tylose HS 100000 YP2 is not an emulsifier and will not emulsify oils into water.
Among other similar chemicals, Tylose HS 100000 YP2 is often used as slime (and gunge, in the UK).
Tylose HS 100000 YP2 is a commonly used thickener in paint&coating formulations.
Solutions of low molecular weight Tylose HS 100000 YP2 grades have a rheology that is near Newtonian and useful for applications that require a stable viscosity regardless of shear.


Tylose HS 100000 YP2 offers efficient and cost-effective options for making crystal clear gel products.
Tylose HS 100000 YP2 is used as coatings and optical brightener additives, coating polymers, filter control additives.
Tylose HS 100000 YP2 is non-ionic, water-soluble materials that provide good properties of thickening, suspending, binding, emulsify, film-forming, stabilize, disperse, retain water and etc.


And Tylose HS 100000 YP2 is widely used in coatings, construction, medicine, food, papermaking and polymer polymerization industry.
Tylose HS 100000 YP2 as well in industrial applications, paint and coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers.
Tylose HS 100000 YP2 finds application in formulating hair styling gels, cosmetic products and personal care formulations.


Tylose HS 100000 YP2 is used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier.
Tylose HS 100000 YP2 is used in broad range of applications includes cosmetic & personnel care, Paint & coating, oilfield, construction, etc.
Tylose HS 100000 YP2 include antiperspirants & deodorants, conditioners, body care, facial care, styling products, sunscreens, liquid soaps, shave gels and foams, wipes (baby and adult), makeup/mascara, AP/Deodorant solids, and lubricant gels.


Tylose HS 100000 YP2 is used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs.
Tylose HS 100000 YP2 is also used extensively in the oil and gas industry as a drilling mud additive under the name .
Tylose HS 100000 YP2 is used as coatings and optical brightener additives, coating polymers, filter control additives


Tylose HS 100000 YP2 offers narrow viscosity ranges, consistent viscosity reproducibility, and excellent solution clarities.
Tylose HS 100000 YP2 grades are defined by their molecular weight or more specifically the viscosity of the aqueous solution that they produce at 2% by weight.
Tylose HS 100000 YP2 is widely used in cosmetics, cleaning solutions, and other household products. Tylose HS 100000 YP2 and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.


With good water retention, thickening, suspension properties, Tylose HS 100000 YP2 offers functional properties and enhance product performancein emulsion-based building materials.
Tylose HS 100000 YP2 has good rheological properties at different shear rates, and has good workability and leveling, not easy to drop, good splash and sag resistance.
Tylose HS 100000 YP2 is also a key ingredient in the formation of large bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble.


-Recommended fields of application of Tylose HS 100000 YP2:
*Interior paints
*Exterior paints


-Application Field of Tylose HS 100000 YP2:
*Interior wall latex paint
*Exterior wall latex paint
*Real stone paint
*Texture paint


-Uses of Tylose HS 100000 YP2:
*Construction uses of Tylose HS 100000 YP2: Cement mortar, Concrete mix, Thickening
*Dyeing: Latex paint, polymer emulsifying, Thickening, water retention, retarding
*Papermaking:Sizing agent,Thickener, water-retaining
*Cosmetic:Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil:Drilling well, completing fluids,Water retention, Thickening,Control of fluid loss


-Typical recommended for thickening and hydration using Tylose HS 100000 YP2.
Disperse Hydroxyethyl cellulose in solution, usually water, and by stir vigorously or using a blender.
Continue to hydrate the HEC in water until completely dissolved.
The thickening will be delayed, this is normal and how the product is designed to work.
(Stir until all particles are dissolved.
This process allows the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.


-Application properties of Tylose HS 100000 YP2:
Tylose HS 100000 yp2 is majnly recommended for ready mixed joint compounds (RMJC).
Tylose HS 100000 YP2 provroes a very creamy and easy wôrkability.
Usually Tylose HS 100000 YP2 is used in combination with Tylose MHPC or MHEC grades to Typical data further improve the workability


-Aplications of Tylose HS 100000 YP2:
• Paint and coating thickener.
• Preparation of water-based latex paints.
• Preparation and synthesis of binder.
• Extraction of petroleum.
• Construction and building materials.
• Manufacture of paper.
• Binder.
• Adhesive.


-Recommended Field Application of Tylose HS 100000 YP2:
*Interior paints
*Solid paints
*Exterior paints
*Silicon resin paints
*Tinters
*Glazes


-Uses of Tylose HS 100000 YP2:
*solubility
*thickening effect
*surface activity


-Applications of Tylose HS 100000 YP2:
*Water-based paint
*Polymerization
*Cosmetics
*Others



PROPERTIES AND APPLICATIONS OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is an important non-ionic, water-soluble cellulose derivative.
Tylose HS 100000 YP2 is a completely odorless, tasteless, and non-toxic white to light-yellow powder that readily dissolves in hot and cold water but is insoluble in most organic solvents.
When dissolved in water, Tylose HS 100000 YP2 forms a transparent viscous solution which has a non-Newtonian behavior.

The hydroxyl groups of Tylose HS 100000 YP2 present in the side chains can be reacted with hydrophobic moities to modify the properties of HEC.
For example, attaching polyether chains onto the cellulose (alkoxylation) yields hydrophobically modified Tylose HS 100000 YP2.
Tylose HS 100000 YP2 is an associative thickener that forms a reversible three-dimensional supramolecular network in solution through intra- and intermolecular associations of the hydrophobic groups.



PHYSICAL AND CHEMICAL PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is soluble in both cold and hot water, but under normal circumstances does not dissolve in most organic solvents.
When the pH value is within the range of 2-12, the change in viscosity is small, but if beyond this range, the viscosity will decrease.
The surface-treated Tylose HS 100000 YP2 can be dispersed in cold water without agglomeration, but dissolution rate is slower, and generally it requires about 30 minutes.
With heat or adjusting the pH value to 8-10, it can be rapidly dissolved.



BENEFITS OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is used as a high performance non-ionic thickener, water-retaining aid and rheological additive in all types of water-based paints and surface coatings, adhesives and many other water-based industrial products.
Tylose HS 100000 YP2 gives these systems excellent rheological properties.

*Additional purification to reduce ash content Excellent salt tolerance
*Imparts slip and lubricity
*Ability to create clear formulations
*Stabilizes emulsion systems
*Surface-treated to aid incorporation into water
*Vegan suitable



CHEMICAL PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water.
Tylose HS 100000 YP2 is insoluble in common organic solvents.
Tylose HS 100000 YP2 is having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding.
Different viscosity range of solution can be prepared.
Tylose HS 100000 YP2 is having exceptionally good salt solubility to electrolyte.



SPECIFICATIONS OF TYLOSE HS 100000 YP2:
- Tylose HS 100000 YP2 provides viscosity at 3,400-5,000 mPa s (cPs) at 1% in water.
- Tylose HS 100000 YP2 melts and forms a gel at about 70 degrees and dissolves well at pH higher than 7
(use an alkali such as Triethanolamine helps to raise the pH value, after dissolving, can adjust the pH later)
- Tylose HS 100000 YP2 can be used in formulations that are acidic down to pH 3 and alkaline up to pH 9.
- Tylose HS 100000 YP2 has no smell



THICKENERS AND BINDERS:
Tylose HS 100000 YP2 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +.

Tylose HS 100000 YP2 has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid.

The role of Tylose HS 100000 YP2 in the aqueous ink is thickened.
The viscosity of the ink added Tylose HS 100000 YP2 increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink.



IMPORTANT PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 can be used as a non-ionic surface active agent.
In addition to thickening, suspending, adhesion, emulsifying, film-forming, dispersing, water-retaining and providing protective colloid properties, but also has the following properties.

1. Tylose HS 100000 YP2 is soluble in hot or cold water, does not precipitate by heat or boiling, and enables it to have a wide range of solubility and viscosity characteristics, as well as non-thermal gelation;
2. Tylose HS 100000 YP2’s non-ionic itself and can coexist with a wide range of other water-soluble polymers, surfactants, and salts, a fine colloidal thickener for the solution containing a high concentration of electrolytes;
3. Tylose HS 100000 YP2's water retention capacity is twice as that of methyl cellulose, and it has better flow-regulating property;
4. Tylose HS 100000 YP2 is stable in viscosity and prevented from mildew.
Tylose HS 100000 YP2 enables the paint to have good can-opening effects and better leveling properties in construction.



PROPERTIES AND FUNCTIONALITY OF TYLOSE HS 100000 YP2:
*Benefit from the non-anionic nature, Tylose HS 100000 YP2 is high stable to broad range of salt, soluble and high resistance even in high brine concentration.
*High-performance thickening, efficient high viscosity build up
*Outstanding pseudoplasticity, Unique shear-thinning characteristic and viscosity reversible
*Film-forming agent, protective colloid action.
*Water retention,maintain water content at formulation
*Excellent compatibility to broad range of water soluble materials or ingredients



PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is a free-flowing powder or granules that range in color from white to slightly yellowish.
Tylose HS 100000 YP2 is odorless and tasteless and contains residual moisture determined by the conditions of production, as well as a small amount of residual salts.
Tylose HS 100000 YP2 can also contain other additives which, for example, regulate the solubility and dispersibility or purposefully influence the development of viscosity.

Depending on the field of application, Tylose HS 100000 YP2 is offered in unmodified and modified form.
The most important properties of Tylose HS 100000 YP2:
*solubility
*thickening effect
*surface activity



THE MANUFACTURING PROCESS OF TYLOSE HS 100000 YP2 IS AS FOLLOWS:
1. Purify the cellulose.
2. Mix it with sodium hydroxide to form swollen alkaline cellulose.
3. Then react it with ethylene oxide.



FEATURE OF TYLOSE HS 100000 YP2:
*Tylose HS 100000 YP2 dissolves readily in both cold water and hot water.
*Aqueous solutions of Tylose HS 100000 YP2 are stable and do not gel at either high or low temperatures.
*Tylose HS 100000 YP2 is a nonionic cellulose ether that remains chemically and physically stable over a wide pH range.
*Tylose HS 100000 YP2 shows excellent performance as athickener, as a water-retention agent, as a suspending and dispersing agent, and as a protective colloid.
*Tylose HS 100000 YP2 can be stored for log periods without degrading significantly, and in aqueous solutions its viscosity remains stable.
*Tylose HS 100000 YP2 is a water-soluble polymer synthesized by the reaction of ethylene oxide with cellulose.

Aqueous solutions of Tylose HS 100000 YP2 have excellent characterisstics for applications as thickeners, water-retention agents, suspending and dispersing agents, and as protective colloids.
In the synthesis of hydroxyethylcellulose, the avarage number of moles of ethylene oxide that combines with each mole of cellulose (MS) is used as an index.
The value of MS in Tylose HS 100000 YP2 is controlled within 1.5 to 2.5.



DRILL INTO BETTER OIL PRODUCTION:
Useful in different forms of oil production, Tylose HS 100000 YP2 is a family of nonionic, water-soluble polymers that can thicken, suspend, bind, stabilize, disperse, form films, emulsify, retain water and provide protective colloid action.
These unique materials can be used to prepare solutions with a wide range of viscosities – including moderate viscosities with normal colloidal properties to maximum viscosities with minimal dissolved solids.

In workover and completion fluids, Tylose HS 100000 YP2 is a viscosifier.
Tylose HS 100000 YP2 helps oil producers provide clear, low-solids fluids that help minimize damage to the formation.
Fluids thickened with Tylose HS 100000 YP2 are easily broken with acid, enzymes or oxidating agents to maximize the potential for hydrocarbon recovery.
In fracturing fluids, Tylose HS 100000 YP2 materials act as carriers for proppant.

These fluids also can be broken down easily with acid, enzymes or oxidating agents.
Using the low-solids concept, drilling fluids that are formulated with Tylose HS 100000 YP2 offer increased penetration rates with good borehole stability.
Property-inhibited fluids can be used in drilling medium-to-hard rock formations, as well as heaving or sloughing shales.
In cementing operations, Tylose HS 100000 YP2 materials reduce hydraulic friction of the slurry and minimize water loss to the formation.



PHYSICAL and CHEMICAL PROPERTIES of TYLOSE HS 100000 YP2:
Type: Interior / Exterior / Solid Paints
Form: Powder
Appearance: white powder
Etherification: high etherification
Particle size: powder
Delayed solubility: yes
Biostability: yes
Viscosity level (according to Höppler): hydroxyethyl cellulose
Viscosity: 4200 - 5500 mPa-s
solution pH: 6-8.5
Moisture content (packed): <6%
Ash (calculated as Na2SO4): <6%
particle size: no more than 10%
Esterification (MS): 2.70
swelling time: 20 minutes.
Bulk densit: 0.45g/l
Lower explosion limits: 30 g/m³
Upper explosion limits:
Density (at 20 °C): 1,1-1,5 g/cm³
Water solubility: (at 20 °C) > 10 g/L

Partition coefficient: log POW < 0
Ignition temperature: > 460 °C
Auto-ignition temperature > 120 °C
Explosive properties The product is considered non-explosive.
Bulk density: 200 - 600 g/l
Conbustion class: 5
Smoulder temperature: 280 °C
pmax: 10 bar
KSt: < 200 bar*m/s
Dust explosion class: ST1
Minimum ignition energy: > 10 mJ
Physical state: Powder
Colour:Whitish
Odour: characteristic
Test method
pH-Value (at 20 °C): 6 - 8 10 g/l
Changes in the physical state
Melting point: n.a.
Initial boiling point and boiling range: n.a.
Flash point: n.a

Appearance Form: powder
Color: beige
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available

Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Chemical formula: variable
Molar mass: variable
Melting point: 140 °C (284 °F; 413 K)
Appearance: white or similar to white powder
Moisture(%): Max. 8.0
PH: 6.0-8.5
Apparent Density: 0.30-0.50 g/ml



FIRST AID MEASURES of TYLOSE HS 100000 YP2:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TYLOSE HS 100000 YP2:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of TYLOSE HS 100000 YP2:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of TYLOSE HS 100000 YP2:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of TYLOSE HS 100000 YP2:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of TYLOSE HS 100000 YP2:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
2-hydroxyethylcelluloseether
ah15
aw15(polysaccharide)
aw15[polysaccharide]
bl15
cellosize
Hydroxyethyl cellulose
HS 100,000 YP2
Cellulose, 2 – hydroxyethyl ether
hydroxyethyl cellulose
Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
Hydroxyethyl Cellulose,2-hydroxyethylcelluloseether
ah15
aw15(polysaccharide)
aw15[polysaccharide]
bl15
cellosize
Hydroxyethyl cellulose – Viscosity 1500 ~ 2500
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
2-Hydroxyethyl cellulose
Cellulose, hydroxyethyl ether
Hydroxyethylcellulose
2-Hydroxyethyl cellulose
Hyetellose
Natrosol
Cellosize
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol


TYLOSE HS 100000 YP2
Tylose HS 100000 YP2 is a white, odorless, tasteless, non-toxic, which is often used as a thickener for methyl hydroxyethyl cellulose or hydroxyethyl cellulose grades in industry agent.
Tylose HS 100000 YP2 is white or light yellowish powder.
Tylose HS 100000 YP2 is natural colloids derived from natural fiber.


CAS Number: 9004-62-0
EC number: 217-576-6


Tylose HS 100000 YP2 is a water soluble, non-ionic, highly esterified hydroxyethyl cellulose powder.
Tylose HS 100000 YP2 provides enhanced biostability, very high thickening and water retention, moderate foam stabilization and high solution clarity, gloss appearance, pigment compatibility and pseudoplasticity.


This grade of Tylose HS 100000 YP2 is particularly well suited for use in interior paints and nonwovens.
Tylose HS 100000 YP2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Tylose HS 100000 YP2 exhibits high compatibility with other raw materials such as surfactant.


Tylose HS 100000 YP2 is easily dissolved in cold or hot water to give crystal-clear solutions of varying viscosities.
Tylose HS 100000 YP2 is nonionic cellulose ether and its solution are more tolerant to the presence of cations,anions and organic solvents.
Tylose HS 100000 YP2 is bio-degradable,non-toxic and environmental friendly natural product.


Tylose HS 100000 YP2 is soluble in cold or hot water to give clarified solution.
Tylose HS 100000 YP2 is a a non-ionic, water-soluble polymer efficient thickening agent and suspending agent.
Tylose HS 100000 YP2 acts as a thickening and stabilizing agent.


Tylose HS 100000 YP2 is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Tylose HS 100000 YP2 exhibits high compatibility with other raw materials such as surfactant.
Hydration time is affected by several factors- pH and temperature of the solution, and concentration level of the Tylose HS 100000 YP2, and the presence of alkalis like TEA, Sodium hydroxide (pH) solution.


Higher pH and higher temperatures DECREASE hydration time, but the higher pH and temperature adjustments too quickly may result in lumping.
It's recommended that the Tylose HS 100000 YP2 be added to room temperature water, with a neutral pH.
Once hydrated, Tylose HS 100000 YP2 can be heated and the pH can be adjusted (typically using TEA) as needed.
(The inhibition period, from the initial wetting to the start of dissolution, hydration time, may vary from 5-25 min)


Tylose HS 100000 YP2 is a non-ionic cellulose ether made through a series of chemical processes, with the natural polymer celluloses as raw materials.
Tylose HS 100000 YP2 is a nonionic, water-soluble polymer.
Tylose HS 100000 YP2 is odorless, tasteless, and non-toxic in the shape of white to off-white powders or granules.


Tylose HS 100000 YP2 can be dissolved in water to form a transparent viscous solution.
Tylose HS 100000 YP2 has thickening, adhesion, dispersion, emulsification, film-formation, suspension, absorption, surface activity, salt tolerance, water retention, providing protective colloids and other properties.


Tylose HS 100000 YP2 forms a non-ionic gel without the effect of electrolyte, suitable for formulations containing electrolyte.
Tylose HS 100000 YP2 is a non-ionic, water-soluble polymer derived from cellulose through a series of chemical and physical processes.
Tylose HS 100000 YP2 is a white to light yellowish, oderless and tastless powder, readily soluble in hot or cold water to form a viscous gel solution.


When pH in solution is within 2 to 12, the solution is quite stable.
Since Tylose HS 100000 YP2 group is nonionic one in water solution, it won't be reacted with other anions or cations and insensitive to the salts.
But Tylose HS 100000 YP2 molecule is capable of generating esterification, etherification and acetal reaction, so Tylose HS 100000 YP2 is possible to make it insoluble in water or improve its properties.


Tylose HS 100000 YP2also has good film-forming ability and surface activity.
Tylose HS 100000 YP2 is a line of nonionic, water-soluble, cellulose based polymers from Dow.
Tylose HS 100000 YP2 is produced by treating reacting alkali-cellulose with ethylene oxide.


This reaction converts some of the hydroxyl groups on the cellulose polymer to hydroxyethyl groups.
Tylose HS 100000 YP2 is a white, free-flowing granular powder and is made by reacting ethylene oxide with alkali-cellulose.
Tylose HS 100000 YP2 is a water-soluble synthetic polymer derived from cellulose in which ethylene oxide groups have been added to the hydroxyl groups.


Tylose HS 100000 YP2 is a nonionic, water-soluble polymer.
Tylose HS 100000 YP2 consists of two components: cellulose and hydroxyethyl side chain.
Tylose HS 100000 YP2 has many properties.


Tylose HS 100000 YP2 is like water retention, thickening, suspension, anti-microbial, high salt tolerance, and ion/PH insensitivity.
Tylose HS 100000 YP2 is a non-ionic, water soluble polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Tylose HS 100000 YP2 will produce crystal clear gel products and thicken the aqueous phase of cosmetic emulsions.


Tylose HS 100000 YP2 can be also be used to efficiently thicken shampoos, body washes and shower gels.
One of the problems normally associated with this and other water-soluble thickeners is the tendency of the particles to agglomerate or lump when first wetted with water.
The high-purity cosmetic grade of Tylose HS 100000 YP2 we offer is an R-grade, designed to be added to water without lumping, and thus greatly facilitating solution preparation.


Tylose HS 100000 YP2 is also the most efficient grade of non-ionic thickener available from the manufacturer.
Hydration of the R-grade particles has been inhibited.
When the particles are added to water, they disperse without lumping, and following a predetermined delay, begin to dissolve.


This process permits the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.
The inhibition period, from the initial wetting to the start of dissolution, is referred to as the hydration time.


This hydration time can vary from 4-25 min.
Hydration time is markedly affected by two factors: pH and temperature of the water.
A higher temperature and a higher pH decrease the hydration time, but a too high temperature or pH can result in lumping.


So, Tylose HS 100000 YP2 is recommended that it be added to room temperature water with a neutral pH.
Once hydrated, Tylose HS 100000 YP2 can be heated and the pH can be adjusted as may be needed.
Tylose HS 100000 YP2 is an excellent thickening agent for cosmetic and personal care formulations.


This nonionic, water soluble polymer, Tylose HS 100000 YP2, offers efficient and cost-effective options for making crystal clear gel products.
Hydroxethyl Cellulose (HEC) has an exceptional skin feel and is the perfect ingredient to make crystal clear serums for water soluble active ingredients.
Recommended Percentages of Tylose HS 100000 YP2:


For Building water phase Viscosity/Stability: 0.1%- 0.5%
For high viscosity crystal clear gel: 1.0%-3.0%
Tylose HS 100000 YP2 features good water retention and an excellent thickening effect.


Tylose HS 100000 YP2's beneficial to various construction projects.
Tylose HS 100000 YP2 is derived from cellulose.
Tylose HS 100000 YP2's nature's most abundant biopolymer in plants, wood, and cotton cell walls.
Tylose HS 100000 YP2 is a gelling and thickening agent derived from cellulose.



USES and APPLICATIONS of TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 include antiperspirants & deodorants, conditioners, body care, facial care, styling products, sunscreens, liquid soaps, shave gels and foams, wipes (baby and adult), makeup/mascara, AP/Deodorant solids, and lubricant gels.
Tylose HS 100000 YP2 is used as a non-ionic cellulose thickener, usually to enhance viscosity, increase concentration by absorbing water, increase viscosity, increase stability, increase degradability, and increase gloss.


Tylose HS 100000 YP2 is used as a thickener for a series of organic solvents.
Tylose HS 100000 YP2 is used in various formulations such as film formulations, emulsifiers, flow regulators, and anti-mildew.
Tylose HS 100000 YP2 is commonly used in the production of water-based resins, the production of interior paints, the adhesive industry, the polymerization of vinyl acetate, the copolymer lactate with vinyl acrylic acid, the hydraulic fracturing process, the production of nonwovens and detergents, cosmetics, Layering of tiles.


In the production of paper, in the production of pet bedding for the production of aqueous polymer emulsions based on ethylene-derived compounds, in the production of pharmaceuticals for the production of various creams and lotions, in the production of toothpaste, in the plastics industry.
Tylose HS 100000 YP2 enhances the viscosity of drilling fluid.


Tylose HS 100000 YP2 acts as a thickening and stabilizing agent.
Tylose HS 100000 YP2 acts as a thickening and stabilizing agent.
Tylose HS 100000 YP2 is used to thicken shampoos, gels, body washes, and add body and after feel to bubble baths, body care products, lotions and creams.


Tylose HS 100000 YP2 is used in broad range of applications includes cosmetic & personnel care, Paint & coating, oilfield, construction, etc.
Tylose HS 100000 YP2 is used as a thickener,binder, stabilizer,film forming, protective colloids and suspending agent.
Tylose HS 100000 YP2 is used as adhesives, bonding aids, filling cement admixtures


Tylose HS 100000 YP2 is used as coatings and optical brightener additives, coating polymers, filter control additives
Tylose HS 100000 YP2 is used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier
Tylose HS 100000 YP2 is used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs.


Tylose HS 100000 YP2 is used in rinses, hair conditioner, hair gel and shaving products.
Tylose HS 100000 YP2 is a hydroxyethyl cellulose powder recommended for use in interior and exterior paints.


Tylose HS 100000 YP2 acts as a non-ionic thickening agent.
Tylose HS 100000 YP2 is easy to use and provides exceptional skin feel, viscosity and stability.
Tylose HS 100000 YP2 offers efficient and cost-effective options for making crystal clear gel products.


Moreover, Tylose HS 100000 YP2 easily disperses into room temperature in water without clumping or forming fish-eyes.
Tylose HS 100000 YP2 is not an emulsifier and will not emulsify oils into water.
Tylose HS 100000 YP2 finds application in formulating hair styling gels, cosmetic products and personal care formulations.


Tylose HS 100000 YP2 can be used in building materials, paints industry, petrochemicals, synthetic resin, ceramic industry, pharmaceutical, food, textile, agriculture, cosmetics, tobacco, ink, papermaking and other industries.
Tylose HS 100000 YP2 is a cellulose ether that is primarily used as a thickener for water-based paint, ink, and adhesive formulations.


Tylose HS 100000 YP2 grades are defined by their molecular weight or more specifically the viscosity of the aqueous solution that they produce at 2% by weight.
Solutions of low molecular weight Tylose HS 100000 YP2 grades have a rheology that is near Newtonian and useful for applications that require a stable viscosity regardless of shear.


Solutions of high molecular weight Tylose HS 100000 YP2, however, behave in a non-Newtonian manner and will have a pseudo-plastic rheology.
This pseudoplasticity makes high viscosity grades of Tylose HS 100000 YP2 an ideal thickener for latex paint applications where the paint must stay on the brush, yet flow out easily upon brushing.


In addition to its useful nature as a thickening agent, Tylose HS 100000 YP2 also provides the benefits of a suspension aid, binder, emulsifier, film former, emulsion stabilizer, dispersant, water retention aid, and protective colloid.
Tylose HS 100000 YP2 offers narrow viscosity ranges, consistent viscosity reproducibility, and excellent solution clarities.


The applications for Tylose HS 100000 YP2 range but in the industrial space it is primarily used for general thickening applications in latex paints, household cleaners and tape-joint compounds.
Hydroxyethyl cellulose(HEC) is a gelling and thickening agent derived from cellulose.


Tylose HS 100000 YP2 is non-ionic, water-soluble materials that provide good properties of thickening, suspending, binding, emulsify, film-forming, stabilize, disperse, retain water and etc.
And Tylose HS 100000 YP2 is widely used in coatings, construction, medicine, food, papermaking and polymer polymerization industry.


In medicine field, Tylose HS 100000 YP2 and methyl cellulose(MHEC) are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.
Tylose HS 100000 YP2 has uses in the cosmetics and personal care industries as a gelling and thickening agent.


In pharmaceuticals, cellulose has been used as an adsorbent, glidant, drug solvent, and suspending agent.
Tylose HS 100000 YP2 is one of the main components of the personal lubricant brand known as K-Y Jelly.
Tylose HS 100000 YP2 can also be found in household cleaning products.


Tylose HS 100000 YP2 is suitable for latex paint, oil drilling, adhesives, and personal care.
Tylose HS 100000 YP2 is mainly used in water-based products.
Tylose HS 100000 YP2 finds applications as a binder, film former, rheology modifer (thickener), adhesion promoter, dispersion stabilizer, extender and slumping reducer in numerous products including paints, inks, adhesives, cosmetics, personal care products, textiles, cements, ceramics and paper products.


One of the most important applications of Tylose HS 100000 YP2 and HMHEC are waterborne architectual coatings.
They are either used alone or in combination with other thickeners.
Infact, Tylose HS 100000 YP2 is the most widely used thickener in exterior latex paints because it is compatible with many coating ingredients such as pigments, surfactants, emulsifiers, preservatives, and binders.


Tylose HS 100000 YP2 is characterized by the formation of viscous gels in water, useful for making paints, adhesives for construction, as well as in the paper and oil industry, among others.
With good water retention, thickening, suspension properties, Tylose HS 100000 YP2 offers functional properties and enhance product performancein emulsion-based building materials.


Tylose HS 100000 YP2 scientific research team specifically for the texture paint, latex paint development of a product, product thickening suspension effect is good, high water retention rate, a small amount of addition, low product unit price can reduce the production cost.
Tylose HS 100000 YP2 is recommended as thickening agent in water-based paint.


Tylose HS 100000 YP2 provides excellent thickening efficiency, color development, open time, and superior resistance to biodegradation.
Tylose HS 100000 YP2 also play a role in the emulsion, dispersion, stability and water retention.
Tylose HS 100000 YP2 has good rheological properties at different shear rates, and has good workability and leveling, not easy to drop, good splash and sag resistance.


Tylose HS 100000 YP2 polymer is a hydroxyethyl ether of cellulose, obtained by treating cellulose with sodium hydroxide and reacting with ethylene oxide.
Tylose HS 100000 YP2 polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps.


They are available as white free-flowing granular powders that easily dissolve in cold and hot water to give transparent solutions with varying viscosities depending on polymer concentration, type and temperature.
Tylose HS 100000 YP2 is a non-ionic soluble cellulose ether, soluble in both cold and hot water, thickening, suspension, adhesion, emulsification, film formation, water retention, protective colloids and other properties, used in coatings.


The fluidity and color pigments, emulsion polymers, surfactants, emulsifiers, defoamers and preservatives are widely compatible with slip.
Tylose HS 100000 YP2 is used to obtain the optimum hydration time to prevent agglomeration caused by accelerators greater than the optimal dissolution rate.
Tylose HS 100000 YP2 powders consolidate many advantages and contribute to the construction field.


Specifically, they apply in paints and coatings, oil drilling, adhesives and sealants.
Tylose HS 100000 YP2 is widely used in cosmetics, cleaning solutions, and other household products. Tylose HS 100000 YP2 and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.


This process is known as hydrophilization.
Tylose HS 100000 YP2 is also used extensively in the oil and gas industry as a drilling mud additive under the name
Tylose HS 100000 YP2 as well in industrial applications, paint and coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers.


Tylose HS 100000 YP2 can be one of the main ingredients in water-based personal lubricants.
Tylose HS 100000 YP2 is also a key ingredient in the formation of large bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble.


Among other similar chemicals, Tylose HS 100000 YP2 is often used as slime (and gunge, in the UK).
Tylose HS 100000 YP2 is a commonly used thickener in paint&coating formulations.
Tylose HS 100000 YP2 is used in paint&coating formulations to increase the viscosity of the paint and to improve its flow and leveling properties.


Tylose HS 100000 YP2 can also be used to make crystal clear, water soluble hair styling gels.
In addition, Hydroxethyl Cellulose (HEC) offers excellent functionality when used in the water phase of emulsions to build viscosity and stability.
However, Hydroxethyl Cellulose (HEC) is not an emulsifier and will not emulsify oils into water.


-Recommended fields of application of Tylose HS 100000 YP2:
*Interior paints
*Exterior paints


-Recommended Field Application of Tylose HS 100000 YP2:
*Interior paints
*Solid paints
*Exterior paints
*Silicon resin paints
*Tinters
*Glazes


-Application properties of Tylose HS 100000 YP2:
Tylose HS 100000 yp2 is majnly recommended for ready mixed joint compounds (RMJC).
Tylose HS 100000 YP2 provroes a very creamy and easy wôrkability.
Usually Tylose HS 100000 YP2 is used in combination with Tylose@ MHPC or MHEC grades to Typical data further improve the workability


-Uses of Tylose HS 100000 YP2:
*solubility
*thickening effect
*surface activity


-Typical recommended for thickening and hydration using Tylose HS 100000 YP2.
Disperse Hydroxyethyl cellulose in solution, usually water, and by stir vigorously or using a blender.
Continue to hydrate the HEC in water until completely dissolved.
The thickening will be delayed, this is normal and how the product is designed to work. (Stir until all particles are dissolved.
This process allows the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.


-Uses of Tylose HS 100000 YP2:
*Construction uses of Tylose HS 100000 YP2: Cement mortar, Concrete mix, Thickening
*Dyeing: Latex paint, polymer emulsifying, Thickening, water retention, retarding
*Papermaking:Sizing agent,Thickener, water-retaining
*Cosmetic:Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil:Drilling well, completing fluids,Water retention, Thickening,Control of fluid loss


-Aplications of Tylose HS 100000 YP2:
• Paint and coating thickener.
• Preparation of water-based latex paints.
• Preparation and synthesis of binder.
• Extraction of petroleum.
• Construction and building materials.
• Manufacture of paper.
• Binder.
• Adhesive.


-Applications of Tylose HS 100000 YP2:
*Water-based paint
*Polymerization
*Cosmetics
*Others


-Application Field of Tylose HS 100000 YP2:
*Interior wall latex paint
*Exterior wall latex paint
*Real stone paint
*Texture paint



PROPERTIES AND FUNCTIONALITY OF TYLOSE HS 100000 YP2:
*Benefit from the non-anionic nature, Tylose HS 100000 YP2 is high stable to broad range of salt, soluble and high resistance even in high brine concentration.
*High-performance thickening, efficient high viscosity build up
*Outstanding pseudoplasticity, Unique shear-thinning characteristic and viscosity reversible
*Film-forming agent, protective colloid action.
*Water retention,maintain water content at formulation
*Excellent compatibility to broad range of water soluble materials or ingredients



FEATURE OF TYLOSE HS 100000 YP2:
*Tylose HS 100000 YP2 dissolves readily in both cold water and hot water.
*Aqueous solutions of Tylose HS 100000 YP2 are stable and do not gel at either high or low temperatures.
*Tylose HS 100000 YP2 is a nonionic cellulose ether that remains chemically and physically stable over a wide pH range.
*Tylose HS 100000 YP2 shows excellent performance as athickener, as a water-retention agent, as a suspending and dispersing agent, and as a protective colloid.
*Tylose HS 100000 YP2 can be stored for log periods without degrading significantly, and in aqueous solutions its viscosity remains stable.
*Tylose HS 100000 YP2 is a water-soluble polymer synthesized by the reaction of ethylene oxide with cellulose.
Aqueous solutions of Tylose HS 100000 YP2 have excellent characterisstics for applications as thickeners, water-retention agents, suspending and dispersing agents, and as protective colloids.
In the synthesis of hydroxyethylcellulose, the avarage number of moles of ethylene oxide that combines with each mole of cellulose (MS) is used as an index.
The value of MS in Tylose HS 100000 YP2 is controlled within 1.5 to 2.5.



IMPORTANT PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 can be used as a non-ionic surface active agent.
In addition to thickening, suspending, adhesion, emulsifying, film-forming, dispersing, water-retaining and providing protective colloid properties, but also has the following properties.
1. Tylose HS 100000 YP2 is soluble in hot or cold water, does not precipitate by heat or boiling, and enables it to have a wide range of solubility and viscosity characteristics, as well as non-thermal gelation;
2. Tylose HS 100000 YP2’s non-ionic itself and can coexist with a wide range of other water-soluble polymers, surfactants, and salts, a fine colloidal thickener for the solution containing a high concentration of electrolytes;
3. Tylose HS 100000 YP2's water retention capacity is twice as that of methyl cellulose, and it has better flow-regulating property;
4. Tylose HS 100000 YP2 is stable in viscosity and prevented from mildew.
Tylose HS 100000 YP2 enables the paint to have good can-opening effects and better leveling properties in construction.



PHYSICAL AND CHEMICAL PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is soluble in both cold and hot water, but under normal circumstances does not dissolve in most organic solvents.
When the pH value is within the range of 2-12, the change in viscosity is small, but if beyond this range, the viscosity will decrease.
The surface-treated Tylose HS 100000 YP2 can be dispersed in cold water without agglomeration, but dissolution rate is slower, and generally it requires about 30 minutes.
With heat or adjusting the pH value to 8-10, it can be rapidly dissolved.



THE MANUFACTURING PROCESS OF TYLOSE HS 100000 YP2 IS AS FOLLOWS:
1. Purify the cellulose.
2. Mix it with sodium hydroxide to form swollen alkaline cellulose.
3. Then react it with ethylene oxide.



PROPERTIES AND APPLICATIONS OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is an important non-ionic, water-soluble cellulose derivative.
Tylose HS 100000 YP2 is a completely odorless, tasteless, and non-toxic white to light-yellow powder that readily dissolves in hot and cold water but is insoluble in most organic solvents.
When dissolved in water, Tylose HS 100000 YP2 forms a transparent viscous solution which has a non-Newtonian behavior.

The hydroxyl groups of Tylose HS 100000 YP2 present in the side chains can be reacted with hydrophobic moities to modify the properties of HEC.
For example, attaching polyether chains onto the cellulose (alkoxylation) yields hydrophobically modified Tylose HS 100000 YP2.
Tylose HS 100000 YP2 is an associative thickener that forms a reversible three-dimensional supramolecular network in solution through intra- and intermolecular associations of the hydrophobic groups.



SPECIFICATIONS OF TYLOSE HS 100000 YP2:
- Tylose HS 100000 YP2 provides viscosity at 3,400-5,000 mPa s (cPs) at 1% in water.
- Tylose HS 100000 YP2 melts and forms a gel at about 70 degrees and dissolves well at pH higher than 7 (use an alkali such as Triethanolamine helps to raise the pH value, after dissolving, can adjust the pH later)
- Tylose HS 100000 YP2 can be used in formulations that are acidic down to pH 3 and alkaline up to pH 9.
- Tylose HS 100000 YP2 has no smell



DRILL INTO BETTER OIL PRODUCTION:
Useful in different forms of oil production, Tylose HS 100000 YP2 is a family of nonionic, water-soluble polymers that can thicken, suspend, bind, stabilize, disperse, form films, emulsify, retain water and provide protective colloid action.
These unique materials can be used to prepare solutions with a wide range of viscosities – including moderate viscosities with normal colloidal properties to maximum viscosities with minimal dissolved solids.

In workover and completion fluids, Tylose HS 100000 YP2 is a viscosifier.
Tylose HS 100000 YP2 helps oil producers provide clear, low-solids fluids that help minimize damage to the formation.
Fluids thickened with Tylose HS 100000 YP2 are easily broken with acid, enzymes or oxidating agents to maximize the potential for hydrocarbon recovery.
In fracturing fluids, Tylose HS 100000 YP2 materials act as carriers for proppant.

These fluids also can be broken down easily with acid, enzymes or oxidating agents.
Using the low-solids concept, drilling fluids that are formulated with Tylose HS 100000 YP2 offer increased penetration rates with good borehole stability.
Property-inhibited fluids can be used in drilling medium-to-hard rock formations, as well as heaving or sloughing shales.
In cementing operations, Tylose HS 100000 YP2 materials reduce hydraulic friction of the slurry and minimize water loss to the formation.



PROPERTIES OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is a free-flowing powder or granules that range in color from white to slightly yellowish.
Tylose HS 100000 YP2 is odorless and tasteless and contains residual moisture determined by the conditions of production, as well as a small amount of residual salts.
Tylose HS 100000 YP2 can also contain other additives which, for example, regulate the solubility and dispersibility or purposefully influence the development of viscosity.
Depending on the field of application, Tylose HS 100000 YP2 is offered in unmodified and modified form.
The most important properties of Tylose HS 100000 YP2:
*solubility
*thickening effect
*surface activity



BENEFITS OF TYLOSE HS 100000 YP2:
Tylose HS 100000 YP2 is used as a high performance non-ionic thickener, water-retaining aid and rheological additive in all types of water-based paints and surface coatings, adhesives and many other water-based industrial products.
Tylose HS 100000 YP2 gives these systems excellent rheological properties.
*Additional purification to reduce ash content Excellent salt tolerance
*Imparts slip and lubricity
*Ability to create clear formulations
*Stabilizes emulsion systems
*Surface-treated to aid incorporation into water
*Vegan suitable



PHYSICAL and CHEMICAL PROPERTIES of TYLOSE HS 100000 YP2:
Type: Interior / Exterior / Solid Paints
Form: Powder
Appearance: white powder
Etherification: high etherification
Particle size: powder
Delayed solubility: yes
Biostability: yes
Viscosity level (according to Höppler): hydroxyethyl cellulose
Viscosity: 4200 - 5500 mPa-s
solution pH: 6-8.5
Moisture content (packed): <6%
Ash (calculated as Na2SO4): <6%
particle size: no more than 10%
Esterification (MS): 2.70
swelling time: 20 minutes.
Bulk densit: 0.45g/l
Lower explosion limits: 30 g/m³
Upper explosion limits:
Density (at 20 °C): 1,1-1,5 g/cm³
Water solubility: (at 20 °C) > 10 g/L

Partition coefficient: log POW < 0
Ignition temperature: > 460 °C
Auto-ignition temperature > 120 °C
Explosive properties The product is considered non-explosive.
Bulk density: 200 - 600 g/l
Conbustion class: 5
Smoulder temperature: 280 °C
pmax: 10 bar
KSt: < 200 bar*m/s
Dust explosion class: ST1
Minimum ignition energy: > 10 mJ
Physical state: Powder
Colour:Whitish
Odour: characteristic
Test method
pH-Value (at 20 °C): 6 - 8 10 g/l
Changes in the physical state
Melting point: n.a.
Initial boiling point and boiling range: n.a.
Flash point: n.a

Appearance Form: powder
Color: beige
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available

Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Chemical formula: variable
Molar mass: variable
Melting point: 140 °C (284 °F; 413 K)
Appearance: white or similar to white powder
Moisture(%): Max. 8.0
PH: 6.0-8.5
Apparent Density: 0.30-0.50 g/ml



FIRST AID MEASURES of TYLOSE HS 100000 YP2:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TYLOSE HS 100000 YP2:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of TYLOSE HS 100000 YP2:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of TYLOSE HS 100000 YP2:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of TYLOSE HS 100000 YP2:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of TYLOSE HS 100000 YP2:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Hydroxyethyl cellulose
HS 100,000 YP2
Cellulose, 2 – hydroxyethyl ether
hydroxyethyl cellulose
Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
Hydroxyethyl Cellulose,2-hydroxyethylcelluloseether
ah15
aw15(polysaccharide)
aw15[polysaccharide]
bl15
cellosize
Hydroxyethyl cellulose – Viscosity 1500 ~ 2500
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
2-Hydroxyethyl cellulose
Cellulose, hydroxyethyl ether
Hydroxyethylcellulose
2-Hydroxyethyl cellulose
Hyetellose
Natrosol
Cellosize



TYLOSE HS 30000 YP 2
Hydroxyethyl cellulose; MB 60000 P2; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE HX 6000 YG4
DESCRIPTION:
TYLOSE HX 6000 YG4 is Hydroxyethylcellulose, chemically modified, with delayed solubility
TYLOSE HX 6000 YG4 is a chemically modified hydroxyethyl cellulose recommended for use in exterior, interior and semi-gloss paints.


CAS: 9004-62-0


TYLOSE HX 6000 YG4 (hydroxyethyl cellulose/Tylose H-grades) are soluble in water at any temperature.
TYLOSE HX 6000 YG4 are nonionic cellulose ethers, which are offered as free flowing powder or in granular form.
TYLOSE HX 6000 YG4 grades have a retarded solubility which ensures a lump free solution in aqueous systems.

PHYSICAL AND CHEMICAL PROPERTIES OF TYLOSE HX 6000 YG4:
Physical state : Solid
Appearance : Powder
Colour : whitish
Odour : characteristic Odour
pH : 5.5 - 8 10g/l
Auto-ignition temperature : > 120 °C
Density : 1.1 - 1.5 g/cm³ 20 °C
Solubility : Water: > 10 g/l @ 20°C
Log Pow : < 0
Explosive properties : Product is not explosive.
Dust may form explosive mixture in air.
Minimum ignition energy : > 10 mJ
Conbustion class : 5
Smoulder temperature : 280 °C pmax : 10 bar
Dust explosion category : ST1 KSt : < 200 bar*m/s
Ignition temperature : > 460 °C


SAFETY INFORMATION ABOUT TYLOSE HX 6000 YG4
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



TYLOSE MB 60000 P2
Hydroxyethyl cellulose; MH 10001 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 10001 P4
Hydroxyethyl cellulose; MH 10007 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 10007 P4
Hydroxyethyl cellulose; MH 15003 P6; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 15003 P6
Hydroxyethyl cellulose; MH 200 YP2; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 200 YP2
Hydroxyethyl cellulose; MH 2000 YP2; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 2000 YP2
TYLOSE MH 2000 YP2 IUPAC Name 5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol TYLOSE MH 2000 YP2 InChI InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3 TYLOSE MH 2000 YP2 InChI Key CWSZBVAUYPTXTG-UHFFFAOYSA-N TYLOSE MH 2000 YP2 Canonical SMILES CC1C(C(C(C(O1)CO)OC2C(C(C(C(O2)COC3C(C(C(C(O3)CO)OC)O)O)OC4C(C(C(C(O4)CO)OC)O)OCCO)O)O)O)O TYLOSE MH 2000 YP2 Molecular Formula (C2H602)x TYLOSE MH 2000 YP2 CAS 9004-62-0 TYLOSE MH 2000 YP2 European Community (EC) Number 618-387-5 TYLOSE MH 2000 YP2 ICSC Number 1559 TYLOSE MH 2000 YP2 RTECS Number FJ5958000 TYLOSE MH 2000 YP2 Physical Description WHITE POWDER. TYLOSE MH 2000 YP2 Solubility Solubility in water: good TYLOSE MH 2000 YP2 Autoignition Temperature 380 °C TYLOSE MH 2000 YP2 Molecular Weight 736.7 g/mol TYLOSE MH 2000 YP2 XLogP3-AA -7.7 TYLOSE MH 2000 YP2 Hydrogen Bond Donor Count 11 TYLOSE MH 2000 YP2 Hydrogen Bond Acceptor Count 21 TYLOSE MH 2000 YP2 Rotatable Bond Count 15 TYLOSE MH 2000 YP2 Exact Mass 736.300109 g/mol TYLOSE MH 2000 YP2 Monoisotopic Mass 736.300109 g/mol TYLOSE MH 2000 YP2 Topological Polar Surface Area 315 Ų TYLOSE MH 2000 YP2 Heavy Atom Count 50 TYLOSE MH 2000 YP2 Formal Charge 0 TYLOSE MH 2000 YP2 Complexity 999 TYLOSE MH 2000 YP2 Isotope Atom Count 0 TYLOSE MH 2000 YP2 Defined Atom Stereocenter Count 0 TYLOSE MH 2000 YP2 Undefined Atom Stereocenter Count 20 TYLOSE MH 2000 YP2 Defined Bond Stereocenter Count 0 TYLOSE MH 2000 YP2 Undefined Bond Stereocenter Count 0 TYLOSE MH 2000 YP2 Covalently-Bonded Unit Count 1 TYLOSE MH 2000 YP2 Compound Is Canonicalized Yes Tylose® MHEC (methyl hydroxyethyl cellulose/Tylose MH-grades) are water soluble, nonionic cellulose ethers, which are offered as free flowing powder or in granular form. Tylose MHEC may contain further additives which for example control the dissolution behavior or the thickening power.Methylhydroxyethyl cellulose. Offers very high water retention, low gloss, low pigment compatibility, low pseudoplasticity, moderate thickening effect, and moderate wet scrub resistance. Exhibits good anti-spattering. Used for paint applications like solid paints, powder paints, limewash paints, cement paints, distempers, and emulsion based plasters.Tylose® MH 2000 YP2 is a water-soluble, non-ionic methyl hydroxyethyl cellulose powder with standard etherification. It provides increased biostability, low gloss appearance, good anti-spattering properties, and moderate wet scrub resistance. This grade of methyl hydroxyethyl cellulose (MHEC) is ideal for use in cement paints, distempers, and lime-wash paints.Constitution: Methyl hydroxyethyl cellulose Appearance:powder Etherification:standard Particle size:powder Delayed solubility:yes Level of viscosity:2000 mPa•sTYLOSE MH 2000 YP2 Biostability:yes TYLOSE MH 2000 YP2 Gloss:low TYLOSE MH 2000 YP2 Pigment Compatibility:low TYLOSE MH 2000 YP2 Anti-spattering:good TYLOSE MH 2000 YP2 Pseudoplasticity:low TYLOSE MH 2000 YP2 Thickening effect:low TYLOSE MH 2000 YP2 Wet scrub resistance:moderate TYLOSE MH 2000 YP2 Water retention:lowCementitious thin bed adhesives are used to adhere ceramic tiles, to build walls of aerated concrete or lime stone bricks and to install exterior insulating finishing systems(EIFS). They offer an easy and light workability,a high efficiency and guarantee a long durability.Cement tile adhesives have to be easy to trowel. They must provide long embedding time, high slip resistance and sufficient adhesion strength. These properties can be influenced by Tylose® MC. Adhesives for block laying are used to build up walls of aerated concrete blocks, sand-lime bricks or standard bricks. EIFS adhesives ensure an excellent bond between substrate and insulating boards. Tylose MC improves the workability of EIFS adhesives and increases both adhesion and sag resistance.Renders are mixtures of mineral binders, aggregates and auxiliaries. Depending on the process, there is a distinction between hand and machine application.Renders are used for base coating, insulation, renovation and decorative purposes. Renders based on cement or cement/hydrated lime can be employed for exterior and interior work.Cement based jointing and trowelling compounds are used for repairing systems and to smooth coarse walls and floors. Grouts are applied to fill the gaps between ceramic or stone tiles.Tylose MC is an important additive ensuring there is sufficient water retention in renders and trowelling compounds. Additional advantages are better workability and an increase of the adhesion strength.Machine applied renders are mixed in continuously or discontinuously working plastering machines.These enable coverage of large wall and ceiling areas by a highly efficient technique. Continuously operating plastering machines need to be fed with premixed renders containing Tylose. Other additives can be added as required.What is TYLOSE MH 2000 YPS? TYLOSE MH 2000 YPS (hydroxyethyl starch) is made from natural sources of starch. TYLOSE MH 2000 YPS increases the volume of blood plasma that can be lost from bleeding or severe injury. Plasma is needed to circulate red blood cells that deliver oxygen throughout the body.TYLOSE MH 2000 YPS is used to treat or prevent hypovolemia (decreased blood plasma volume, also called "shock") that may occur as a result of serious injury, surgery, severe blood loss, burns, or other trauma.TYLOSE MH 2000 YPS may also be used for purposes not listed in this medication guide.Important Information You should not receive this medication if you have a bleeding or blood clotting disorder, congestive heart failure, kidney disease, or urination problems not caused by hypovolemia (decreased blood plasma volume).TYLOSE MH 2000 YPS can harm your kidneys. Call your doctor at once if you have any of these symptoms of kidney damage: swelling, rapid weight gain, unusual tiredness, nausea, vomiting, feeling short of breath, red or pink urine, painful or difficult urination, or little or no urinating.Before taking this medicine You should not receive this medication if you are allergic to TYLOSE MH 2000 YPS, or if you have:a bleeding or blood clotting disorder;kidney disease;congestive heart failure; or urination problems not caused by hypovolemia (decreased blood plasma volume).If possible before you receive TYLOSE MH 2000 YPS, tell your doctor if you have:liver disease;a history of heart disease; or if you are allergic to corn.FDA pregnancy category C. It is not known whether TYLOSE MH 2000 YPS will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.It is not known whether TYLOSE MH 2000 YPS passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.In an emergency situation it may not be possible to tell your caregivers about your health conditions, or if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received TYLOSE MH 2000 YPS.How is TYLOSE MH 2000 YPS given?TYLOSE MH 2000 YPS is injected into a vein through an IV. A healthcare provider will give you this injection.Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are receiving TYLOSE MH 2000 YPS. Your blood will also need to be tested daily during treatment.What happens if I miss a dose?Because you will receive TYLOSE MH 2000 YPS in a clinical setting, you are not likely to miss a dose.What happens if I overdose?Since TYLOSE MH 2000 YPS is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.What should I avoid after receiving TYLOSE MH 2000 YPS?Follow your doctor's instructions about any restrictions on food, beverages, or activity.TYLOSE MH 2000 YPS side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Tell your caregivers right away if you have:wheezing or gasping for breath, rapid breathing, sweating, and anxiety;a light-headed feeling, like you might pass out;weak pulse, slow breathing;chest pain, fever, chills, cough; or easy bruising, unusual bleeding, or any bleeding that will not stop.Rare but serious side effects may include:severe headache, vision or speech problems, mental changes;drooping eyelids, loss of feeling in your face, tremors, trouble swallowing; or severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.TYLOSE MH 2000 YPS can harm your kidneys. Call your doctor at once if you have any of these symptoms of kidney damage: swelling, rapid weight gain, unusual tiredness, nausea, vomiting, feeling short of breath, red or pink urine, painful or difficult urination, or little or no urinating.Common side effects may include:mild itching or skin rash;mild headache;muscle pain; or swollen glands, mild flu symptoms.This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.See also:TYLOSE MH 2000 YPS side effects (in more detail)TYLOSE MH 2000 YPS dosing information Usual Adult Dose for Hypovolemia:Dosage for Acute Use in Plasma Volume Expansion: 500 to 1000 mL IVMaintenance dose: Total dosage and rate of infusion depends on the amount of blood or plasma lost and the resultant hemoconcentration.Maximum dose: Doses more than 1500 mL per day (approximately 20 mL per kg of body weight) are usually not required although higher doses have been used in postoperative and trauma patients with severe blood loss.Dosage in Leukapheresis: 250 to 700 mL to which citrate anticoagulant has been added and administered to the input line of the centrifugation apparatus at a ratio of 1:8 to 1:13 to venous whole blood.Comments:TYLOSE MH 2000 YPS and citrate should be thoroughly mixed to assure effective anticoagulation.TYLOSE MH 2000 YPS admixtures of 500 to 560 mL with citrate concentrations up to 2.5% are compatible for 24 hours at room temperature.Uses:For treatment of hypovolemia when plasma volume expansion is desired.This drug in leukapheresis improves the harvesting and increasing the yield of granulocytes by centrifugal means.What other drugs will affect TYLOSE MH 2000 YPS? Other drugs may interact with TYLOSE MH 2000 YPS, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Pharmacology and mechanism of action Pentastarch is a synthetic colloid volume expander that is used to maintain vascular volume in animals with circulatory shock. It is prepared from hydroxyethyl starch and is derived from amylopectin. There are two hydroxyethyl starch preparations: TYLOSE MH 2000 YPS and pentastarch. TYLOSE MH 2000 YPS (6%) has an average molecular weight of 450,000 and colloid osmotic pressure of 32.7. Pentastarch (10%) has an average molecular weight of 280,000 and colloid osmotic pressure of 40. Because TYLOSE MH 2000 YPS is a larger molecular weight compound than pentastarch, it tends to remain in the vasculature and prevent loss of intravascular volume and tissue edema. After administration, pentastarch will be retained in the vasculature and prevent loss of intravascular volume and tissue edema. Other colloids used are dextrans (Dextran 40 and Dextran 70). TYLOSE MH 2000 YPS and the dextrans are discussed in other sections.Pharmacology and mechanism of action Hydroxyethyl starch is a synthetic colloid volume expander that is used to maintain vascular volume in animals with circulatory shock. It is a modified branched-chain glucose polymer derived from amylopectin sources such as potatoes, sorghum, or maize. The hydroxyethyl starch preparations include tetrastarch, TYLOSE MH 2000 YPS, and pentastarch. TYLOSE MH 2000 YPS (6%) has an average molecular weight of 200 kDa (kilodaltons) and a colloid osmotic pressure of approximately 30. Pentastarch (10%) has an average molecular weight of 200 kDa and a colloid osmotic pressure of 30-60. Tetrastarch (VetStarch) 6% has a molecular weight of 130 kDa and a colloid osmotic pressure of 36. The number of molecular substitutions determine whether it is TYLOSE MH 2000 YPS, pentastarch, or hexastarch. TYLOSE MH 2000 YPS has the most molecular substitutions and tends to remain longest in the vasculature. TYLOSE MH 2000 YPS is cleared much more slowly than tetrastarch. Although TYLOSE MH 2000 YPS is prevented from hydrolysis in blood, thereby prolonging intravascular expansion, this property also is associated with accumulation in the reticuloendothelial system, skin, liver, and kidney.TYLOSE MH 2000 YPS is a more cost-effective synthetic colloid. Advantages of TYLOSE MH 2000 YPS include maintenance of plasma oncotic effect for up to 24 hours following administration and the ability to give as a rapid bolus.10,11 However, unlike plasma, there are no functional proteins present in hydroxyethyl starch solutions and a negative effect on coagulation has been demonstrated in healthy equids.10,12 Further, a 2013 review of the use of colloids as volume replacement in critically ill humans found an increased risk of mortality and acute kidney injury in patients receiving TYLOSE MH 2000 YPS.13 As such, the use of TYLOSE MH 2000 YPS in horses with underlying renal insufficiency is cautioned, and its use is restricted to those with clinical signs of acute hypoproteinemia. Recently tetrastarch (6%) was evaluated and shown to have a more sustained effect on COP with fewer adverse coagulopathic effects than TYLOSE MH 2000 YPS.14 Both TYLOSE MH 2000 YPS and tetrastarch can be dosed at 10 mL/kg.
TYLOSE MH 20009 P2
CAS Number 9032-42-2
Product form: Mixture
Product name: Tylose MH 20009 P2



APPLICATIONS


Uses of Tylose MH 20009 P2:

Water retention aid
Thickening agent
Protective colloid
Suspending agent
Binder and stabilizer


Pharmaceutical Applications of Tylose MH 20009 P2:

Tylose MH 20009 P2 is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations.
Furthermore, Tylose MH 20009 P2 has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.


Tylose MH 20009 P2 is used as thickener and suspending agent in latex paints, paint removers, detergents, and hard surface cleaners.
Moreover, Tylose MH 20009 P2 is used as a protective colloid in textile inks and vinyl chloride polymerization.
Tylose MH 20009 P2 is used as a binder, thickener, and water retention aid in various building products.

Tylose MH 20009 P2 is used in adhesives used for tanning.
Besides, Tylose MH 20009 P2 is used as a general-purpose food additive.

Tylose MH 20009 P2 is used in pharmaceutical tablets and formulations.
In addition, Tylose MH 20009 P2 is used in wallpaper paste.

Tylose MH 20009 P2 is used for slip casts in ceramics.
Additionally, Tylose MH 20009 P2 is used in cosmetic creams and lotions.

Tylose MH 20009 P2 is used as a protective colloid in water based paints (prevents pigment flocculation).
More to that, Tylose MH 20009 P2 is used for film and sheeting.
Tylose MH 20009 P2 is used as a substitute for water-soluble gums.

Tylose MH 20009 P2 is used to render paper greaseproof.
Further to that, Tylose MH 20009 P2 is used as a laxative.


Industrial Processes of Tylose MH 20009 P2 with risk of exposure:

Pulp and Paper Processing
Painting (Pigments, Binders, and Biocides)
Working with Glues and Adhesives
Leather Tanning and Processing
Textiles (Printing, Dyeing, or Finishing)


Applications of Tylose MH 20009 P2:

cements
mortars
mayonnaise
dressing
desserts
pharmaceutical tablets and formulations
wallpaper paste
slip casts in ceramics
latex paints
paint removers
cosmetic creams and lotions
Methyl cellulose and its derivatives


Tylose MH 20009 P2 is used as protective colloid in water based paints to prevent flocculation of pigment.
Furthermore, Tylose MH 20009 P2 is a synthetic substance that is used as a thickening and emulsifying agent in many products, including foods, pharmaceuticals, and cosmetics.

Tylose MH 20009 P2 has been shown to inhibit the activity of certain enzymes, such as amylase, lipase, and protease.
In addition to these properties, Tylose MH 20009 P2 is also known for its high degree of thermal stability and light resistance.

Tylose MH 20009 P2 can be used in a wide range of applications due to its versatility and low cost.


Properties of Tylose MH 20009 P2:

Good water solubility
Water retention
Dispersing
Stable PH value
Surface activity
Thickening
Adhexive
Film-smoothability
Mold resisitance


Recommended use of Tylose MH 20009 P2:

Rheological Additive Special applications Coating material Additive for mortar

Restrictions on use:

There is no information available on applications that are not advised.


Some Uses of Tylose MH 20009 P2:

Water retention aid
Thickening agent
Protective colloid
Suspending agent
Binder and stabilizer


Tylose MH 20009 P2 is a Methyl ether of hydroxyethylcellulose.
Moreover, Tylose MH 20009 P2 uses and applications include: Binder, thickener, pigment, foamfiller stabilizer, dispersant, emulsifier, plasticizer, viscous control agent, sedimenting aid, protective colloid in coatings, paints, resins, mining, batteries, insecticidal products, rubber, textile, leather, ceramics, suspension polymerization, pharmaceuticals.

Tylose MH 20009 P2 is used as adhesion promoter in tile cements; water retention aid, thickener in sprayable plasters, mortar, stucco, fillers.
Besides, Tylose MH 20009 P2 is used as viscous control agent, stabilizer in cosmetics.

Tylose MH 20009 P2 is a gelling and thickening agent derived from cellulose.



DESCRIPTION


Tylose MH 20009 P2 is a synthetic substance that is used as a thickening and emulsifying agent in many products, including foods, pharmaceuticals, and cosmetics.
In addition, Tylose MH 20009 P2 has been shown to inhibit the activity of certain enzymes, such as amylase, lipase, and protease.

In addition to these properties, Tylose MH 20009 P2 is also known for its high degree of thermal stability and light resistance.
Tylose MH 20009 P2 can be used in a wide range of applications due to its versatility and low cost.

Additionally, Tylose MH 20009 P2 is a polymer that is derived from natural sources, with or without chemical modification.



PROPERTIES


Physical state: Solid
Appearance: Powder
Colour: whitish
Odour: odourless
Odour threshold: No data available
pH: 6 – 8 10g/l
Relative evaporation rate (butylacetate=1): Not specifically applicable
Melting point / Freezing point: Melting point: Not specifically applicable
Freezing point: Not specifically applicable
Boiling point: Not specifically applicable
Flash point: Not specifically applicable
Auto-ignition temperature: > 170 °C
Flammability (solid, gas): No data available
Vapour pressure:
Vapour pressure: Not specifically applicable
Vapour pressure at 50 °C: Not specifically applicable
Relative density:
Relative vapour density at 20 °C: Not specifically applicable
Density:
Density: 1.1 – 1.5 g/cm³ 20 °C
Relative density: Not specifically applicable
Solubility:
Water: > 10 g/l @ 20°C
Log Pow: < 0
Viscosity, kinematic: Not specifically applicable
Viscosity, dynamic: Not specifically applicable
Explosive properties: Product is not explosive. Dust may form explosive mixture in air.
Explosive limits: No data available
Minimum ignition energy: > 10 mJ
Fat solubility: No data available
Conbustion class: 5
Smoldering temperature: >450 °C
pmax: 10 bar
Dust explosion category: ST1
KSt: < 200 bar*m/s
Ignition temperature: > 400 °C



FIRST AID


Description of necessary first-aid measures

First-aid measures after inhalation:

Remove person to fresh air and keep comfortable for breathing.
Call a doctor.


First-aid measures after skin contact:

Wash skin with plenty of water.


First-aid measures after eye contact:

Rinse immediately with plenty of water, also under the eyelids.
Consult an ophthalmologist if irritation persists.


First-aid measures after ingestion:

Rinse mouth.
If symptoms persist, call a physician.


Symptoms caused by exposure:

Symptoms/effects after skin contact:

May cause sensitisation of susceptible persons by skin contact.


Symptoms/effects after eye contact:

May cause eye irritation.


Medical attention and special treatment:

Treatment:

Treat symptomatically.



HANDLING AND STORAGE


Precautions for safe handling:

Ensure good ventilation of the work station.
Wear personal protective equipment.
Avoid dust formation.

Dust may form explosive mixture in air.
Keep away from sources of ignition - No smoking.


Hygiene measures:

Do not eat, drink or smoke when using Tylose MH 20009 P2.
Always wash hands after handling the product.


Conditions for safe storage, including any incompatibilities:

Storage conditions:

Material is hygroscopic.
Protect from atmospheric moisture and water.


Information on mixed storage:

No special storage requirements.



SYNONYMS


HYDROXYETHYL METHYL CELLULOSE
CELLULOSE METHYL HYDROXYETHYL ETHER
METHYL HYDROXYETHYL CELLULOSE
METHYL 2-HYDROXYETHYL CELLULOSE
Cellulose,2-hydroxyethylmethylether
Hydroxythyl Methyl Cellulose
HydroxythylMethylCellulose(Hemc)
ethane-1,2-diol
(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
Cellulose
2-hydroxyethyl methyl ether
Hydroxyethyl methyl cellulose
Methyl hydroxyethyl cellulose
Culminal MHEC
Tylose MHB
TYLOSE MH 30000 YP4
Hydroxyethyl cellulose; MH 4000 KG4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 4000 KG4
Hydroxyethyl cellulose; MH 4000 KG4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 4000 P2
Hydroxyethyl cellulose; MH 6000 YP4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 6000 YP4
Hydroxyethyl cellulose; MH 6000 YP4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 60004 P6
Hydroxyethyl cellulose; MH 6002 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 6002 P4
Hydroxyethyl cellulose; MH 60027 P6; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 60027 P6
Hydroxyethyl cellulose; MHB 3000 P2; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MH 60027 P6
TYLOSE MH 60027 P6 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MH 60027 P6 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MH 60027 P6 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification. TYLOSE MH 60027 P6 provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, These products, offered under the brand, are highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.These nonionic, water-soluble polymers can thicken, suspend, bind, emulsify, form films, stabilize, disperse, retain water, and provide protective colloid action. They are readily soluble in water and can be used to prepare solutions with a wide range of viscosities. They have outstanding tolerance for dissolved electrolytes. Application range - Tile adhesives - Skim coat - Tile grouts - Repair mortars - Self-leveling flooring compounds - Cement or gypsum-based mortars - Painting - Ceramics - Textile - Detergents Key properties -Improves water retention -Improves adhesive strength -Improves sag resistance -Improve construction efficiency Packaging and storage A. Standard packed in 25 KG per paper plastic composite bag B. Big bags or other special packages are possible on request Weight/20' container: approx. 10 metric tons with pallets, approx. 14 metric tons without pallets Weight/40' container: approx. 24 metric tons with pallets, approx. 26 metric tons without pallets Stored in its original packaging in a dry and place with temperature below 30℃. It is recommended to use SLEO® MHEC within 2 years. Safety notes The data presented above is in accordance with the present state of our knowledge, but doesn’t absolve the user from carefully checking it all immediately on receipt. We reserve the right to alter product constantly within the scope of technical progress or new developments. The recommendations made above should be checked by preliminary trials because of conditions during processing over which we have no control of, especially where other companies' raw materials are also being used. The working mechanism of methyl hydroxyethyl cellulose, MHEC (Mw = 2.5 · 105 g/mol, DSmethyl = 1.81, MShydroxyethyl = 0.15) as water retention agent in cement was investigated. First, the hydrocolloid was characterized and its performance as non-ionic water retention agent was determined employing the filter paper test. Also, water sorption and swelling of individual MHEC fibers under conditions of different humidities were monitored by ESEM imaging. Second, its working mechanism was established. It was found that at low dosages, MHEC achieves water retention by intramolecular sorption of water and concomitant swelling while at higher dosages, MHEC molecules agglomerate into large hydrocolloidal microgel particles (d > 1 μm) which effectively plug the pores in the mortar matrix. MHEC association was evidenced by an exponential increase in solution viscosity as concentration rises, a strong increase in the hydrodynamic diameter of solved MHEC molecules, and a noticeable reduction of surface tension. Related Categories Cellulose, Materials Science, Natural Polymers and Biopolymers, Polymer Science, Polymers More... extent of labeling 0.06-0.50 mol hydroxyethyl per mol cellulose (M.S.) 8 wt. % hydroxyethyl 26 wt. % methoxy 1.3-2.2 mol methyl per mol cellulose (D.S.) surface tension 45-55 dyn/cm, 20 °C, 0.1 wt. % viscosity 15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.) transition temp flocculation range 60-90 °C (0.5 wt. %) storage temp. room temp What is TYLOSE MH 60027 P6? TYLOSE MH 60027 P6 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MH 60027 P6 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MH 60027 P6 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification. Characteristics of TYLOSE MH 60027 P6 TYLOSE MH 60027 P6 has various features. They include: 1. Appearance TYLOSE MH 60027 P6 can be either white, pale yellow or yellowish-white, or grayish-white. It is also odorless. 2. Solubility TYLOSE MH 60027 P6 is soluble in water (cold or hot water). Although TYLOSE MH 60027 P6 is insoluble in the most organic solvent but soluble in a binary organic solvent and organic solvent water system. Its highest concentration depends on the viscosity and its solubility varies with viscosity. The lower the viscosity, the greater the solubility and vice versa. 3. PH stability TYLOSE MH 60027 P6 is stable within the range of 3.0 – 11.0 and its viscosity is hardly affected but a PH value out of this range will decrease its viscosity. 4. Metabolism TYLOSE MH 60027 P6 is an inert substance and its odorless. It is widely used in food and medicine applications due to its inability to undergo metabolism. 5. Surface Activity It can be used as a dispersant, protective agent, and emulsifier due to its surface-active function in an aqueous solution. 6. Mildew Resistance In the long term storage, TYLOSE MH 60027 P6 is a good mildew resistance due to its good viscosity stability.Its mildew resistance capacity is higher than the hydroxyethyl cellulose. 7. Water Retention TYLOSE MH 60027 P6 serves as an effective water retention agent due to its high viscosity in aqueous solution.Its water retention capacity is greater than the methylcellulose. 8. Ash Content Hot water washing is used in the preparation process of TYLOSE MH 60027 P6, thereby making the ash content very low. 9. Thermal Gel When the TYLOSE MH 60027 P6 solution is being heated to a certain temperature, it becomes less transparent with the formation of precipitate and gel but if cooled, it goes back to its original state of solution. Common Uses of TYLOSE MH 60027 P6 TYLOSE MH 60027 P6 can be used as: Ø Adhesive Ø Protective colloid Ø Thickening agent Ø Film-forming agent Ø Emulsifier Ø Lubricant Ø Suspending agent Industrial Applications of TYLOSE MH 60027 P6 TYLOSE MH 60027 P6 is widely used in different industries, which are: · Polymerization · Ceramic · Cosmetics · Construction · Food and Beverages · Pharmaceuticals · Paint and Coatings · Ink and Oil Drilling Summary TYLOSE MH 60027 P6 as said earlier is a derivative of methylcellulose. It is a non-ionic cellulose ether produced from the raw material of high purity cotton. Its odorless characteristics and inability to metabolize makes it widely used in food and medicine applications. TYLOSE MH 60027 P6 water retaining capacity and thickening ability makes it suitable for water-based latex painting, ink and oil drilling, construction materials, etc.As it is widely used in diverse applications, getting TYLOSE MH 60027 P6 from a reputable TYLOSE MH 60027 P6 supplier assures you of the best product for personal or industrial use.
TYLOSE MHB 3000 P2
TYLOSE MHB 3000 P2 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MHB 3000 P2 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MHB 3000 P2 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification.TYLOSE MHB 3000 P2 provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, These products, offered under the brand, are highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.These nonionic, water-soluble polymers can thicken, suspend, bind, emulsify, form films, stabilize, disperse, retain water, and provide protective colloid action. They are readily soluble in water and can be used to prepare solutions with a wide range of viscosities. They have outstanding tolerance for dissolved electrolytes.Application range- Tile adhesives- Skim coat- Tile grouts- Repair mortars- Self-leveling flooring compounds- Cement or gypsum-based mortars- Painting- Ceramics- Textile- DetergentsKey properties-Improves water retention-Improves adhesive strength-Improves sag resistance-Improve construction efficiencyPackaging and storageA. Standard packed in 25 KG per paper plastic composite bagB. Big bags or other special packages are possible on requestWeight/20' container: approx. 10 metric tons with pallets, approx. 14 metric tons without palletsWeight/40' container: approx. 24 metric tons with pallets, approx. 26 metric tons without palletsStored in its original packaging in a dry and place with temperature below 30℃.It is recommended to use SLEO® MHEC within 2 years.Safety notesThe data presented above is in accordance with the present state of our knowledge, but doesn’t absolve the user from carefully checking it all immediately on receipt. We reserve the right to alter product constantly within the scope of technical progress or new developments. The recommendations made above should be checked by preliminary trials because of conditions during processing over which we have no control of, especially where other companies' raw materials are also being used. The working mechanism of methyl hydroxyethyl cellulose, MHEC (Mw = 2.5 · 105 g/mol, DSmethyl = 1.81, MShydroxyethyl = 0.15) as water retention agent in cement was investigated. First, the hydrocolloid was characterized and its performance as non-ionic water retention agent was determined employing the filter paper test. Also, water sorption and swelling of individual MHEC fibers under conditions of different humidities were monitored by ESEM imaging. Second, its working mechanism was established. It was found that at low dosages, MHEC achieves water retention by intramolecular sorption of water and concomitant swelling while at higher dosages, MHEC molecules agglomerate into large hydrocolloidal microgel particles (d > 1 μm) which effectively plug the pores in the mortar matrix. MHEC association was evidenced by an exponential increase in solution viscosity as concentration rises, a strong increase in the hydrodynamic diameter of solved MHEC molecules, and a noticeable reduction of surface tension.Related Categories Cellulose, Materials Science, Natural Polymers and Biopolymers, Polymer Science, Polymers More...extent of labeling 0.06-0.50 mol hydroxyethyl per mol cellulose (M.S.)8 wt. % hydroxyethyl26 wt. % methoxy1.3-2.2 mol methyl per mol cellulose (D.S.)surface tension 45-55 dyn/cm, 20 °C, 0.1 wt. %viscosity 15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.)transition temp flocculation range 60-90 °C (0.5 wt. %)storage temp. room tempWhat is TYLOSE MHB 3000 P2?TYLOSE MHB 3000 P2 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MHB 3000 P2 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MHB 3000 P2 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification.Characteristics of TYLOSE MHB 3000 P2TYLOSE MHB 3000 P2 has various features. They include: 1. AppearanceTYLOSE MHB 3000 P2 can be either white, pale yellow or yellowish-white, or grayish-white. It is also odorless. 2. SolubilityTYLOSE MHB 3000 P2 is soluble in water (cold or hot water). Although TYLOSE MHB 3000 P2 is insoluble in the most organic solvent but soluble in a binary organic solvent and organic solvent water system. Its highest concentration depends on the viscosity and its solubility varies with viscosity. The lower the viscosity, the greater the solubility and vice versa. 3. PH stabilityTYLOSE MHB 3000 P2 is stable within the range of 3.0 – 11.0 and its viscosity is hardly affected but a PH value out of this range will decrease its viscosity. 4. MetabolismTYLOSE MHB 3000 P2 is an inert substance and its odorless. It is widely used in food and medicine applications due to its inability to undergo metabolism. 5. Surface ActivityIt can be used as a dispersant, protective agent, and emulsifier due to its surface-active function in an aqueous solution. 6. Mildew ResistanceIn the long term storage, TYLOSE MHB 3000 P2 is a good mildew resistance due to its good viscosity stability.Its mildew resistance capacity is higher than the hydroxyethyl cellulose. 7. Water RetentionTYLOSE MHB 3000 P2 serves as an effective water retention agent due to its high viscosity in aqueous solution.Its water retention capacity is greater than the methylcellulose. 8. Ash ContentHot water washing is used in the preparation process of TYLOSE MHB 3000 P2, thereby making the ash content very low. 9. Thermal GelWhen the TYLOSE MHB 3000 P2 solution is being heated to a certain temperature, it becomes less transparent with the formation of precipitate and gel but if cooled, it goes back to its original state of solution. Common Uses of TYLOSE MHB 3000 P2TYLOSE MHB 3000 P2 can be used as:Ø AdhesiveØ Protective colloidØ Thickening agentØ Film-forming agentØ EmulsifierØ LubricantØ Suspending agent Industrial Applications of TYLOSE MHB 3000 P2TYLOSE MHB 3000 P2 is widely used in different industries, which are:· Polymerization· Ceramic· Cosmetics· Construction· Food and Beverages· Pharmaceuticals· Paint and Coatings· Ink and Oil Drilling SummaryTYLOSE MHB 3000 P2 as said earlier is a derivative of methylcellulose. It is a non-ionic cellulose ether produced from the raw material of high purity cotton. Its odorless characteristics and inability to metabolize makes it widely used in food and medicine applications. TYLOSE MHB 3000 P2 water retaining capacity and thickening ability makes it suitable for water-based latex painting, ink and oil drilling, construction materials, etc.As it is widely used in diverse applications, getting TYLOSE MHB 3000 P2 from a reputable TYLOSE MHB 3000 P2 supplier assures you of the best product for personal or industrial use.
TYLOSE MHB 3000 P2
Tylose MHB 3000 P2 is soluble in cold water, flocculates at elevated temperatures.
Tylose MHB 3000 P2 is a white, yellowish-white or grayish-white powder or granules, hygroscopic after drying.
Tylose MHB 3000 P2 is water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.


CAS Number: 9032-42-2
EC Number: 618-528-0


Tylose MHB 3000 P2 is a gelling and thickening agent derived from cellulose.
Tylose MHB 3000 P2 stands for methyl hydroxyethyl cellulose.
Tylose MHB 3000 P2 is considered to be non-toxic.


Tylose MHB 3000 P2 is water soluble, nonionic cellulose ethers, which are offered as free flowing powder or in granular form.
Tylose MHB 3000 P2 is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Tylose MHB 3000 P2 could be dissolved in hot or cold water to form a transparent solution with a particular viscosity.


Tylose MHB 3000 P2 is more resistant to saline, easily soluble in water and has higher gel temperature.
Tylose MHB 3000 P2 is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.
Tylose MHB 3000 P2 enhances the liquidity and pumpability, thus improving the efficiency of the flooring.


Tylose MHB 3000 P2 is also called as Hydroxyethyl Methyl Cellulose HEMC.
Tylose MHB 3000 P2, also known as Methylcellulose and colloquium, is an organic compound methyl hydroxyethyl cellulose uses in various cosmetic and medical applications, the primary one being as a thickening agent.


Tylose MHB 3000 P2 is a water soluble.
Tylose MHB 3000 P2 can be described as a modified cellulose polymer consisting of methyl, ethyl, and hydroxyethyl side chains.
Tylose MHB 3000 P2, in the form of a powder, is a thickening agent.


Tylose MHB 3000 P2 is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Tylose MHB 3000 P2 appears to be white powder and is odorless and tasteless.


Tylose MHB 3000 P2 is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.
Tylose MHB 3000 P2 could be soluble in water to form a transparent solution.
Tylose MHB 3000 P2 provides viscosity, which can be used as an anti – precipitation agent.


Tylose MHB 3000 P2 is nonionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
The term HPMC stands for hydroxypropyl methyl cellulose, while the term Tylose MHB 3000 P2 stands for methyl hydroxyethyl cellulose.
Tylose MHB 3000 P2 is a non-ionic cellulose ether that widely used in construction materials.


Tylose MHB 3000 P2 is excellent compatibility with other components and high biostability.
Tylose MHB 3000 P2 can be used in water-based latex paints and printing inks.
Tylose MHB 3000 P2 is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.


Compared to other cellulose ether chemistries, the methylcellulose derivatives have a slightly more Newtonian flow characteristic which provides increased high-shear (ICI) viscosity.
Tylose MHB 3000 P2 is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.


Tylose MHB 3000 P2 is also known as HEMC, Methyl Hydroxyethyl Cellulose, which can be used as highly efficient water retention agent, stabilizer, adhesives and film-forming agent in construct.
Tylose MHB 3000 P2 is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.


Tylose MHB 3000 P2 offers many of the same advantages as other methyl cellulose derivatives, such as effective thickening and moisture retention.
Tylose MHB 3000 P2 has a good stability even though in alkaline environment and provide a good stability in heat environment.
Tylose MHB 3000 P2 is ether of cellulose and ethylene oxide mainly used as adhesive protective gelatin, thicker agent and stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets.


Tylose MHB 3000 P2 may contain further additives which for example control the dissolution behavior or the thickening power.
Tylose MHB 3000 P2 is a kind of odorless, tasteless, non-toxic white powder or granule.
Tylose MHB 3000 P2 dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.


Tylose MHB 3000 P2 is a white, odorless powder.
These two are important as construction chemicals and can be used as thickeners, water retention agents, and air-entraining agents.
Tylose MHB 3000 P2 is a gelling and thickening agent that is derived from cellulose.


The chemical formula of this compound is variable because the number of unit structures per Tylose MHB 3000 P2 molecule can vary.
Tylose MHB 3000 P2's pH value exists between 5.0 and 8.0.
Tylose MHB 3000 P2 is water soluble nonionic cellulose ethers, which are offered as free flowing powder or in granular form cellulose.


In cold water Tylose MHB 3000 P2 will swell into colloidal solution and its solubility is not influenced by PH value.
Similar to methyl cellulose while being added to Hydroxyethyl groups.
Tylose MHB 3000 P2 is medium-high viscosity construction grade Methyl Hydroxyethyl Cellulose widely used in building materials.


The properties of Tylose MHB 3000 P2 and methylcellulose are similar, but the presence of hydroxyethyl makes Tylose MHB 3000 P2 cellulose more soluble in water, the solution is more compatible with salt and has a higher aggregation temperature.
Tylose MHB 3000 P2 is a non-ionic cellulose ether made from natural high polymer cellulose.


Tylose MHB 3000 P2 is also called as Hydroxyethyl Methyl Cellulose HEMC.
Tylose MHB 3000 P2 is a non-ionic cellulose ether made from natural high polymer cellulose.
Tylose MHB 3000 P2 is a white, yellow-white or off-white powder or granules, hygroscopic after drying.


Tylose MHB 3000 P2 is a methylcellulose based cellulose.
Tylose MHB 3000 P2 could dissolve in water and form a clear solution with specific viscosity.
Tylose MHB 3000 P2 dissolves fast and without mass, which helps to simplify the mixing process.
The cold water disperses the model product, can make the mix more quick and convenient, and does not produce the mass.



USES and APPLICATIONS of TYLOSE MHB 3000 P2:
Tylose MHB 3000 P2 provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, Tylose MHB 3000 P2 is highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.


Tylose MHB 3000 P2 used as a high efficient water retention agent, stabilizer, adhesive and film-forming agent in kinds of building mateTylose MHB 3000 P2 is used as a food additive. rials.
Tylose MHB 3000 P2 is a water soluble substance.
For industrial usages, Tylose MHB 3000 P2's different forms are: water retention agent, stabilizer, adhesives and film forming agent.


Tylose MHB 3000 P2 ensures fast hydration for reliable performance.
Tylose MHB 3000 P2 offers premium level of water retention and strong adhesion.
According to experts, Tylose MHB 3000 P2 also improves the performance of cement and gypsum based materials.


Tylose MHB 3000 P2 have a good stability even though in alkaline environment and provide a good stability in heat environment.
As a non-ionic cellulose ether, Tylose MHB 3000 P2 powder has a good stabilization and thickening effect in paint, which can make the paint produce good wear resistance.
In the food industry, Tylose MHB 3000 P2 is used as adhesion, emulsification, film formation, thickening, suspending, dispersing, water retention agents, etc.


Tylose MHB 3000 P2 offers very good temperature stability and compatibility with many materials including surfactants and polymers such as CMC, starch ether, guar gum and alginates.
Tylose MHB 3000 P2 can also shows delayed solubility.


Due to its high degree of methoxylation, Tylose MHB 3000 P2 is the only cellulose derivative with the best water retention, which is the only reason why MHEC is sold for use in cement-based wall putties and mortars.
Tylose MHB 3000 P2 enhances the viscosity of the water-based paint remover and organic solvent, so that the paint remover will not flow out of the surface of the workpiece.


The most significant Tylose MHB 3000 P2 uses include its use in the production of adhesives, cosmetics, paper and textiles, pharmaceuticals, paint, and a host of other industrial applications.
Cellulose ether can be used in any area where thickening, gelling, emulsifying, stabilizing processes and providing water retention and good workability properties are required.


Tylose MHB 3000 P2 has stronger water retention than methylcellulose, stronger viscosity stability, mildew resistance, and dispersion than hydroxyethyl cellulose.
Tylose MHB 3000 P2 is tasteless and odorless, and in medicine, it is ingested by patients to relieve constipation, diarrhea, and hemorrhoids.
Mainly, these are used in cement and gypsum-based dry mix mortar to increase bond strength, workability, and water retention.


Tylose MHB 3000 P2 is also playing useful roles in kinds of building materials.
Tylose MHB 3000 P2 is non surface treated grade, used for various mortars especially under dry mix system.
To avoid the lump formation, Tylose MHB 3000 P2 is suggested to use it in dry from before the water is added, as it dissolve rapidly.


Tylose MHB 3000 P2 is a water soluble substance.
To avoid the lump formation, Tylose MHB 3000 P2 is suggested to use it in dry form before the water is added, as it dissolve rapidly.
Tylose MHB 3000 P2 could dissolve in water and form a clear solution with specific viscosity.


Tylose MHB 3000 P2 is widely used in drymix mortar industry, oil drilling, detergent and paint & costings etc.
In daily chemicals, Tylose MHB 3000 P2 is used as an additive for toothpaste, cosmetics, and detergent.
Tylose MHB 3000 P2 is also used to control consistency, flow and leveling, high shear viscosity, and storage stability of interior and exterior flat emulsion paints.


Tylose MHB 3000 P2 has several properties used in the pharmaceutical and construction industries.
Tylose MHB 3000 P2 is used water based paint and paint remover.
Tylose MHB 3000 P2 improves the adhesiveness of wet strength and sheet extrusion.


Tylose MHB 3000 P2 is a high-efficiency water retention agent because its aqueous solution has good hydrophilicity.
In decorative applications, Tylose MHB 3000 P2's found most often as a component of toothpaste and cough syrups.
Tylose MHB 3000 P2 offers premium level of water retention and strong adhesion.


According to experts, Tylose MHB 3000 P2 also improves the performance of cement and gypsum based materials.
Tylose MHB 3000 P2 ensures fast hydration for reliable performance.
Tylose MHB 3000 P2 can be used as a protective colloids, suspending agent and binder and stabilizer.


The lubricity of Tylose MHB 3000 P2 can greatly improve the mortar workability (such as improve the bond strength of mortar, reduce water absorption, and enhance anti-sag of mortar), which is helpful for improving work efficiency.
Tylose MHB 3000 P2 is widely used in wall putty and tile adhesives.


Tylose MHB 3000 P2 is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
Tylose MHB 3000 P2 is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
Tylose MHB 3000 P2 is extruded concrete plank.


Tylose MHB 3000 P2 is also playing useful roles in kinds of building materials.
Tylose MHB 3000 P2 can thicken, suspend, agglutinate, float, and provide protective colloid, for this reason, it is mainly used as an adhesive, thickener, and emulsifying additive.


Tylose MHB 3000 P2 cellulose powder is widely used in the building industry.
Tylose MHB 3000 P2 is non surface treated grade, used for various mortars especially under dry mix system.
Tylose MHB 3000 P2 is a kind of Cellulose Ethers, which is mainly used as adhesive protective gelatin, thicker agent, stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets.


Tylose MHB 3000 P2 can be used in tile adhesive, joint filler, self-leveling mortar, plaster, skim coat, paint and coatings, etc.
Tylose MHB 3000 P2 has good viscosity stability and anti-mildew degeneration during long-term storage.
Tylose MHB 3000 P2 has various properties such as thickening, emulsifying, binding, forming, protective colloid and water retention.


Tylose MHB 3000 P2 is widely used to maintain water content in waterborne coatings and varnishes, control the rheology and consistency of waterborne coatings, stabilize pigments and fillers, as adhesives and viscosity control agents in enamel, as thickeners in printing inks, and as thickeners in textile coatings.
Tylose MHB 3000 P2 has a good anti-mildew ability because it contains hydroxyethyl groups.


For industrial usages, Tylose MHB 3000 P2's different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Tylose MHB 3000 P2 can be used in different building materials: Tile adhesive, Cement mortar, Joint filler, Self-levelling compound, External wall insulation, Gypsum based plaster, Ceramic extrusion.


Except for the construction industry, Tylose MHB 3000 P2 is also used in the food industry, daily chemicals, and other fields.
Tylose MHB 3000 P2 is also used in cement-based tile adhesives and grouts.
Tylose MHB 3000 P2 is widely used in drymix mortar industry, oil drilling, detergent and paint & costings etc.


Methyl Hydroxyethyl Cellulose (MHEC) alone or in combination is the most widely used cellulose in mortar formulations.
Tylose MHB 3000 P2 enhances the processing performance of extruded products, with high bonding strength and lubrication.
Tylose MHB 3000 P2 has a good performance in coatings and building materials.


-Medicine:
You may have taken Tylose MHB 3000 P2 without even knowing it.
That's because Tylose MHB 3000 P2 has been used in manufacturing pharmaceutical products for decades.
Tylose MHB 3000 P2 works as an excipient (a sense included with an active drug that binds together all ingredients).
Furthermore, Tylose MHB 3000 P2 can be used to coat pills and help slow down their release into the body.


-Dispersing Agent:
When mixed with other chemicals, Tylose MHB 3000 P2 works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.
This makes Tylose MHB 3000 P2 useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.


-Applications of Tylose MHB 3000 P2:
*Adhesives
*Binders
*Coatings
*Construction


-Moisturizer and surfactant:
Tylose MHB 3000 P2 is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
Tylose MHB 3000 P2 is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Tylose MHB 3000 P2 can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.


-Concrete Mixes:
Concrete mixes using Tylose MHB 3000 P2 are commonly used for their smoothness and strength.
Tylose MHB 3000 P2 is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.


-Uses of Tylose MHB 3000 P2:
*Construction: Cement mortar, Concrete mix , Gypsum-based hand and machine plasters
*Painting: Latex paint, polymer emulsified, Thickening, water retention, retarding Interior paints Exterior paints
*Silicone resin-based paints, Jamb mortars Papermaking: Sizing agent, Thickener, water-retaining
*Cosmetics: Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil: Widely used in well drilling, filling liquids, Water retention, Thickening, Liquid loss control industrial applications


-Cosmetics:
Tylose MHB 3000 P2 is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Like other uses for methyl hydroxyethyl cellulose, Tylose MHB 3000 P2's used to increase the viscosity of these products and make them easier to apply.


-Cement plaster:
Tylose MHB 3000 P2 improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability.
Tylose MHB 3000 P2 enhance liquidity and pumpability, thus improving working efficiency.
High water retention, prolong the working time of mortar, improve work efficiency, and facilitate the formation of high mechanical strength during solidification period.
Control the infiltration of air, thus eliminating the microcracks of the coating and forming the ideal smooth surface.


-Tile adhesive:
Tylose MHB 3000 P2 makes the dry mixing ingredients easy to mix, and will not produce a mass, thus saving working time.
As the application is faster and more effective, Tylose MHB 3000 P2 can improve the construction and reduce the cost.
Tylose MHB 3000 P2 improve the efficiency of tiling by lengthening the cooling time. Provides excellent adhesion effect.
Special development model with high anti-skid resistance can be provided.
Self-leveling the ground material.


-Applications:
Tylose MHB 3000 P2 is used tile Grouts, Tiles Adhesive, White Cement based wall putty, Water based Latex Paint, Printing Ink, Oil Drilling, Dry & Wet Mortar series, Construction & Building Material, Retaining Water & improving constructability, Thickening Agent, Decorative Plaster, Gypsum, Detergent etc.


-Paper Production:
Due to the low toxicity of Tylose MHB 3000 P2 and its ability to improve the properties of paper while decreasing production costs, MHE has gained wide acceptance in the paper manufacturing industry.
Tylose MHB 3000 P2 can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage; it can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.


-Herbicide:
Some farmers use Methylcellulose as an herbicide. When mixed with water and sprinkled on certain plants, Tylose MHB 3000 P2 can help prevent growth or kill the plant entirely.
Tylose MHB 3000 P2 helps the herbicide stay in place without being washed away by water or carried away by the wind.


-Cement:
Tylose MHB 3000 P2 helps increase the efficiency of cement by prolonging water retention and hydration reactions.
This helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Tylose MHB 3000 P2 can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.


-Oil drilling:
Tylose MHB 3000 P2 uses is also used in oil drilling operations to thicken liquids used in the exploration process.
This helps ensure that Tylose MHB 3000 P2 can be pumped through pipes without dripping or spilling, making them less effective at their intended function.


-Paints and coatings:
Tylose MHB 3000 P2, also known as MHEC and Methylcellulose, is a thickening agent used in paints and coatings.
Tylose MHB 3000 P2 can help prevent paint from sagging and dripping when it dries.
The combination can also help provide the color with extra adhesion, making Tylose MHB 3000 P2 helpful in constructing buildings.
Tylose MHB 3000 P2 is commonly used as a thickening agent in decorative paints.
Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Tylose MHB 3000 P2 provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.
Tylose MHB 3000 P2 also helps make paint that has been applied easier to clean.


-Soil Stabilizers:
Tylose MHB 3000 P2 is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Tylose MHB 3000 P2 can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Tylose MHB 3000 P2 allows nutrients to remain available to plants over more extended periods than untreated fertilizers.


-Binding agent:
Tylose MHB 3000 P2 is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Tylose MHB 3000 P2 is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.


-Food Production:
Tylose MHB 3000 P2 is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Tylose MHB 3000 P2 serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Tylose MHB 3000 P2 is also added to baked goods, salad dressings, and salad gums.
Tylose MHB 3000 P2 helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.


-Gypsum plaster:
Tylose MHB 3000 P2 improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability to enhance the mobility and pumpability.
Thus, the work efficiency is improved.
High water retention, longer working time of mortar, and high mechanical strength during solidification.
A high quality surface coating is formed by controlling the consistency of the mortar.


-Masonry mortar:
Strengthen the adhesion of the surface of the masonry, and enhance the water retention, so as to improve the strength of mortar.
Improve the lubrication and plasticity so as to improve the construction performance, and use the mortar made of “guaranteed” cellulose ether to make it easier to apply and save time, and improve the cost-effectiveness.

The model with special high water retention can be used for high absorbent bricks.
Tylose MHB 3000 P2 is used to fill the material.
Excellent water retention, Tylose MHB 3000 P2 can prolong cooling time and improve working efficiency.

Tylose MHB 3000 P2has high lubricity, make use easier, smooth.
Tylose MHB 3000 P2 improves the anti-contractility and crack resistance and improve the surface quality.
Tylose MHB 3000 P2 provides smooth and uniform texture, and make the joint surface more cohesive.


-Thickening agent:
Tylose MHB 3000 P2 uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, Tylose MHB 3000 P2 coats the hair strands to protect them from water damage.
Because Tylose MHB 3000 P2 is water-soluble, it does not cause build-up on hair strands after repeated use of the product containing it.



PROPERTIES OF TYLOSE MHB 3000 P2:
● Good thickening / thickening efficiency
● Available in a wide range of molecular weight and viscosity
● Excellent properties as a water-retaining agent
● Excellent resistance to dissolved inorganic salts
● Excellent solution clarity
● Low toxicity and environmental protection



WHAT IS THE DIFFERENCE BETWEEN HPMC AND TYLOSE MHB 3000 P2?
HPMC and Tylose MHB 3000 P2 are modified cellulose forms that are mainly used as gelling agents for thickening properties in different items.
The key difference between HPMC and Tylose MHB 3000 P2 is that the gel temperature of HPMC is around 60 – 75 ℃ depending on the group content and different production techniques, whereas the gel temperature of MHEC is usually higher than 80 ℃.



KEY PROPERTIES OF TYLOSE MHB 3000 P2:
- Improves workability
- Reduce water absorption
- Increase adhesion strength



PHYSICAL PROPERTIES OF TYLOSE MHB 3000 P2:
Tylose MHB 3000 P2 appears to be white powder and is odorless and tasteless.
Tylose MHB 3000 P2 is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Tylose MHB 3000 P2 will swell into colloidal solution and its solybility is not influenced by PH value.
Similar to methyl cellulose while being added to Hdroxyethyl groups.
Tylose MHB 3000 P2 is more resistant to saline, easily soluble in water and has higher gel temperature.



WHY TYLOSE MHB 3000 P2 IS BEING PREFERRED OVER HPMC FOR CELLULOSE ETHER?
Cellulose Ether is derived from Cellulose and is a water-soluble compound used in several industries.
It finds its usage mainly in the construction, food, pharmaceutical, and cosmetics industries.
Specifically, Cellulose Ether is primarily used in the construction sector as it acts as a binder, thickener, and water retention agent in construction.

There are different grades of Cellulose Ether, which have their applicability and properties.
The two primary grades of Cellulose Ether HPMC (Hydroxypropyl Methyl Cellulose) and Tylose MHB 3000 P2 have varied similarities, yet one is more preferred than the other in recent days.

Nowadays, Tylose MHB 3000 P2 grade of Cellulose Ether is more preferred than the HPMC grade in the construction industry.
Though, both are being utilized widely for increasing bond strength and water retention capacity of a dry mixture of cement and gypsum, few properties differentiate them.
The first property differentiating Tylose MHB 3000 P2 from HPMC is gel temperature; the gel temperature of MHEC is higher than that of Tylose MHB 3000 P2.

The gel temperature of HPMC is around 60°c - 70°c, which varies as per its content and production technique; however, the gel temperature of Tylose MHB 3000 P2 is generally more than 80°C, which makes it a better alternative.
Tylose MHB 3000 P2 has better thermal stability owing to its high gel temperature, causing better water retention capacity during summers in South Asian Countries.

Furthermore, Tylose MHB 3000 P2 has a more significant number of Hydrophilic groups in its structure, eventually leading to more hydrophilicity than the HPMC grade.
Having more Hydrophilic groups makes Tylose MHB 3000 P2 better in water retention, and hence it is preferred more.
In addition, the prices of Tylose MHB 3000 P2 grades have been lesser than that of HPMC, making them more economical to use.
In India, the prices of Cellulose Ether, with respective to all grades, have been marginally increasing from the first week of April.

According to ChemAnalyst, “Tylose MHB 3000 P2grade would be chosen over HPMC grade in countries including India as summers have already approached.
Construction industries would go for having cellulose ether with higher gel temperature and better hydrophilicity.
Furthermore, the Indian domestic market of Cellulose Ether is most likely to showcase stagnant to a marginal rise in the prices.”



PHYSICAL and CHEMICAL PROPERTIES of TYLOSE MHB 3000 P2:
Molecular Weight:858.9
Hydrogen Bond Donor Count:10
Hydrogen Bond Acceptor Count:24
Rotatable Bond Count:17
Exact Mass:858.39440297
Monoisotopic Mass:858.39440297
Topological Polar Surface Area:332
Heavy Atom Count:58
Complexity:884
Defined Atom Stereocenter Count:20
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Molecular Weight: 858.9
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 24
Rotatable Bond Count: 17
Exact Mass: 858.39440297
Monoisotopic Mass: 858.39440297
Topological Polar Surface Area: 332 Ų
Heavy Atom Count: 58
Formal Charge: 0
Complexity: 884
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 20
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Appearance: White powder
Loss on drying: ≤5%
PH: 4.0-8.0



FIRST AID MEASURES of TYLOSE MHB 3000 P2:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated lothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TYLOSE MHB 3000 P2:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TYLOSE MHB 3000 P2:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TYLOSE MHB 3000 P2:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TYLOSE MHB 3000 P2:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of TYLOSE MHB 3000 P2:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
Cellulose,2-hydroxyethyl methyl ether
Hydroxyethyl methyl cellulose
Methyl hydroxyethyl cellulose
Culminal MHEC
Tylose MHB
Walocel MT 10.000GO
Walocel MKS 8.000PP11
Tylopur MH
Tylose MHB 1000
Tylose MHB 30000
Tylose MH 4000
Tylose MH 300P
Tylose MH 1000P
Tylose MH 1000
Tylose MH 2000
Tylose MH 50
Tylose MH 300
Tylose MH 2000P
Tylose MH 20
Tylose MH 4000P
Tylose MH
2-Hydroxyethyl methyl cellulose
Tylose MH 200XP
Tylose 4000
Tylose MH 200K
Tylose MHB 50
Unishot A 10
Tylose MH 2000XP
Metolose SEB 15T
Benecel ME 233P
SNB 100T
Culminal MHEC 15000PFF
Metolose SEB 02T
Tylose MH 10000K
Tylose MHB 3000P
Tylose MHB 3000
Tylose MG 50
Metolose SEB 30T
Metolose SEB 30000
Modocoll E 20
Modocoll E 100
SEW 04T
Tylose MH 6000XP
Cesca MHEC 6000PR
Metolose SEB 04T
Walocel MKX 30.000PF01
Metolose SEB 4000
Metolose SEW 4000
Tylopur MH 300
OMC 181
Metolose SE
Tylose MN
Metolose SEB 15000
Tylose MH 200KG4
Hymetellose
Culminal MHEC 300000PR
SHV-WF
Metolose SEW 30T
Tylose MH 200YP2
Tylose MH 10000
Culminal MHEC 40000
MH 4000
SNB
SNB (binder)
90SHV-WF
Walocel VP-M 20677
Tylose MG 15003P6
Tylose MH 50G4
Walocel MKX 60000PF01
Walocel MKX 40000PP01
Walocel VP-M 20678
Walocel MKX 45000
Walocel 400PFV
Marpolose ME 300000
Tylopur MH 50G4
Tylose MH 3001P6
SEB 4000
Culminal C 8315
Methocel 267
Metolose SNB 60T
Tylose MB 10000P6
Walocel MKX 20000PF40
Walocel MW 15000GB
Tylose MH 10000P6
Mecellose HEMC
51990-47-7
457603-24-6
1089092-83-0
1884332-09-5
2097341-71-2
2-hydroxyethyl methyl cellulose
Cellulose, 2-hydroxyethyl methyl ether
Methyl hydroxyethyl cellulose
9032-42-2
methyl 2-hydroxyethyl cellulose
ethane-1,2-diol
(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane




TYLOSE MHB 3000 P2
Hydroxyethyl cellulose; MHF 10015 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulosecas no: 9004-62-0
TYLOSE MHB 3000 YP2
TYLOSE MHB 3000 YP2 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MHB 3000 YP2 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MHB 3000 YP2 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification. TYLOSE MHB 3000 YP2 provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, These products, offered under the brand, are highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.These nonionic, water-soluble polymers can thicken, suspend, bind, emulsify, form films, stabilize, disperse, retain water, and provide protective colloid action. They are readily soluble in water and can be used to prepare solutions with a wide range of viscosities. They have outstanding tolerance for dissolved electrolytes. Application range - Tile adhesives - Skim coat - Tile grouts - Repair mortars - Self-leveling flooring compounds - Cement or gypsum-based mortars - Painting - Ceramics - Textile - Detergents Key properties -Improves water retention -Improves adhesive strength -Improves sag resistance -Improve construction efficiency Packaging and storage A. Standard packed in 25 KG per paper plastic composite bag B. Big bags or other special packages are possible on request Weight/20' container: approx. 10 metric tons with pallets, approx. 14 metric tons without pallets Weight/40' container: approx. 24 metric tons with pallets, approx. 26 metric tons without pallets Stored in its original packaging in a dry and place with temperature below 30℃. It is recommended to use SLEO® MHEC within 2 years. Safety notes The data presented above is in accordance with the present state of our knowledge, but doesn’t absolve the user from carefully checking it all immediately on receipt. We reserve the right to alter product constantly within the scope of technical progress or new developments. The recommendations made above should be checked by preliminary trials because of conditions during processing over which we have no control of, especially where other companies' raw materials are also being used. The working mechanism of methyl hydroxyethyl cellulose, MHEC (Mw = 2.5 · 105 g/mol, DSmethyl = 1.81, MShydroxyethyl = 0.15) as water retention agent in cement was investigated. First, the hydrocolloid was characterized and its performance as non-ionic water retention agent was determined employing the filter paper test. Also, water sorption and swelling of individual MHEC fibers under conditions of different humidities were monitored by ESEM imaging. Second, its working mechanism was established. It was found that at low dosages, MHEC achieves water retention by intramolecular sorption of water and concomitant swelling while at higher dosages, MHEC molecules agglomerate into large hydrocolloidal microgel particles (d > 1 μm) which effectively plug the pores in the mortar matrix. MHEC association was evidenced by an exponential increase in solution viscosity as concentration rises, a strong increase in the hydrodynamic diameter of solved MHEC molecules, and a noticeable reduction of surface tension. Related Categories Cellulose, Materials Science, Natural Polymers and Biopolymers, Polymer Science, Polymers More... extent of labeling 0.06-0.50 mol hydroxyethyl per mol cellulose (M.S.) 8 wt. % hydroxyethyl 26 wt. % methoxy 1.3-2.2 mol methyl per mol cellulose (D.S.) surface tension 45-55 dyn/cm, 20 °C, 0.1 wt. % viscosity 15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.) transition temp flocculation range 60-90 °C (0.5 wt. %) storage temp. room temp What is TYLOSE MHB 3000 YP2? TYLOSE MHB 3000 YP2 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MHB 3000 YP2 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MHB 3000 YP2 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification. Characteristics of TYLOSE MHB 3000 YP2 TYLOSE MHB 3000 YP2 has various features. They include: 1. Appearance TYLOSE MHB 3000 YP2 can be either white, pale yellow or yellowish-white, or grayish-white. It is also odorless. 2. Solubility TYLOSE MHB 3000 YP2 is soluble in water (cold or hot water). Although TYLOSE MHB 3000 YP2 is insoluble in the most organic solvent but soluble in a binary organic solvent and organic solvent water system. Its highest concentration depends on the viscosity and its solubility varies with viscosity. The lower the viscosity, the greater the solubility and vice versa. 3. PH stability TYLOSE MHB 3000 YP2 is stable within the range of 3.0 – 11.0 and its viscosity is hardly affected but a PH value out of this range will decrease its viscosity. 4. Metabolism TYLOSE MHB 3000 YP2 is an inert substance and its odorless. It is widely used in food and medicine applications due to its inability to undergo metabolism. 5. Surface Activity It can be used as a dispersant, protective agent, and emulsifier due to its surface-active function in an aqueous solution. 6. Mildew Resistance In the long term storage, TYLOSE MHB 3000 YP2 is a good mildew resistance due to its good viscosity stability.Its mildew resistance capacity is higher than the hydroxyethyl cellulose. 7. Water Retention TYLOSE MHB 3000 YP2 serves as an effective water retention agent due to its high viscosity in aqueous solution.Its water retention capacity is greater than the methylcellulose. 8. Ash Content Hot water washing is used in the preparation process of TYLOSE MHB 3000 YP2, thereby making the ash content very low. 9. Thermal Gel When the TYLOSE MHB 3000 YP2 solution is being heated to a certain temperature, it becomes less transparent with the formation of precipitate and gel but if cooled, it goes back to its original state of solution. Common Uses of TYLOSE MHB 3000 YP2 TYLOSE MHB 3000 YP2 can be used as: Ø Adhesive Ø Protective colloid Ø Thickening agent Ø Film-forming agent Ø Emulsifier Ø Lubricant Ø Suspending agent Industrial Applications of TYLOSE MHB 3000 YP2 TYLOSE MHB 3000 YP2 is widely used in different industries, which are: · Polymerization · Ceramic · Cosmetics · Construction · Food and Beverages · Pharmaceuticals · Paint and Coatings · Ink and Oil Drilling Summary TYLOSE MHB 3000 YP2 as said earlier is a derivative of methylcellulose. It is a non-ionic cellulose ether produced from the raw material of high purity cotton. Its odorless characteristics and inability to metabolize makes it widely used in food and medicine applications. TYLOSE MHB 3000 YP2 water retaining capacity and thickening ability makes it suitable for water-based latex painting, ink and oil drilling, construction materials, etc.As it is widely used in diverse applications, getting TYLOSE MHB 3000 YP2 from a reputable TYLOSE MHB 3000 YP2 supplier assures you of the best product for personal or industrial use.
Tylose MHF 10015 P4
Tylose MHF 10015 P4 is a water-soluble, non-ionic, modified methyl hydroxyethyl cellulose powder with standard etherification. It provides fast consistency development, very high sag resistance and water demand, moderate water retention and influence on cement hydration, and high heat stability. This grade of methyl hydroxyethyl cellulose (MHEC) is ideal for use in cement tile adhesives.

CAS NO: 9032-42-2
EC NO: 618-528-0

IUPAC NAMES
ethane-1,2-diol;(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol;(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

SYNONYMS

9032-42-2
methyl 2-hydroxyethyl cellulose
METHYL HYDROXYETHYL CELLULOSE
METHYL 2-HYDROXYETHYL CELLULOSE
Hymetellose
Cellulose,2-hydroxyethylmethylether
'Tylose'® MH 300
Hydroxythyl Methyl Cellulose
HydroxythylMethylCellulose(Hemc)
HEMC
HYDROETHYLMETHYL CELLULOSE (HEMC)
METHYL HYDROXYETHYL CELLULOSE (20-40CPS: 2% IN WATER)
Methyl Hydroxyethyl Cellulose (20-40mPa.s, 2% in Water at 20deg C)
Methyl hydroxyethyl cellulose (20-40cps
(20-40MPa.s, 2% in Water at 20deg C)
Methyl Hydroxyethyl Cellulose
HEMC(Hydroxyethyl Methyl Cellulose)
Methyl Hydroxyethyl Cellulose (MHEC)
Methylhydroxyethylcellulose for synthesis
HYDROXYETHYL METHYL CELLULOSE
CELLULOSE METHYL HYDROXYETHYL ETHER
Hydroxyethyl Methyl Cellulose(Hemc)
METHYLHYDROXYETHYLCELLULOSE FOR SYNTHESI


Tylose MH 10015 P4
DOCUMENTS

Tylose MH 10015 P4 is a water soluble, nonionic, modified methylhydroxyethylcellulose powder with standard etherification. It provides rapid development of consistency, very high sag resistance and water demand, moderate water retention and influence on cement hydration, and high thermal stability. This grade of methylhydroxyethylcellulose (MHEC) is ideal for use in cement tile adhesives.


TYLOSE MHF 10015 P4

Areas of use for TYLOSE MHF 10015 P4:
In paint strippers
Friction fuel thickener

CELLULOSE ETER (HEC) HYDROXYETHYL CELLULOSE
TYLOSE MHF 10015 P4 is a nonionic cellulose ether which is produced using natural polymeric cellulose as a raw material and through a series of etherization reactions.

TYLOSE MHF 10015 P4
General detail
TYLOSE MHF 10015 P4 AREAS OF USE:

TYLOSE MHF 10015 P4 in the latex paint composition prevents gel from gelling, contributes to its dispersion, stabilizes the latex paint and increases the viscosity of the component. TYLOSE MHF 10015 P4 has good compatibility with other materials such as pigments, auxiliary substances, fillers and salts in its components.

Coatings thickened with TYLOSE MHF 10015 P4 have good rheology at different cutting speeds and are pseudoplastic.

The machinability and leveling properties of TYLOSE MHF 10015 P4 are good: brush, roller, sprayer and
can be applied with other construction methods; it doesn't drip, sag or bounce back easily.

TYLOSE MHF 10015 P4 high viscosity is primarily used as an adhesive for finishing and finishing fluids in oil drilling. TYLOSE MHF 10015 P4 low viscosity is used as a fluid loss additive. Among the various solutions required for drilling, finishing, cementing and crushing, TYLOSE MHF 10015 P4 offers good fluidity and mud stability.

TYLOSE MHF 10015 P4 is used as a binder, thickener, stabilizer and dispersant in toothpastes, detergents and cosmetics.

TYLOSE MHF 10015 P4 offers easy application thanks to its shear resistance and its binding effect in products thanks to its water retention function.
TYLOSE MHF 10015 P4 helps create movies.

TYLOSE MHF 10015 P4 CHARACTERISTICS:
TYLOSE MHF 10015 P4 has thickening, binding, dispersing, film-forming and suspending properties.

When the pH of TYLOSE MHF 10015 P4 aqueous solution is between 2 and 12, the viscosity is stable. If TYLOSE MHF 10015 P4 exceeds this range, acidic or alkaline oxidative degradation occurs and viscosity decreases.

The viscosity of TYLOSE MHF 10015 P4 aqueous solution decreases as the temperature increases and the viscosity can be recovered as the temperature drops to the original temperature. TYLOSE MHF 10015 P4 If there is no high salt concentration, no gel or precipitate will form when the solution is heated to the boiling point; TYLOSE MHF 10015 P4 is therefore very resistant to temperature.

TYLOSE MHF 10015 P4 aqueous solution is a nonionic system and can be used in other water soluble polymers, surfactants, salts, etc. can be found with. For this reason, TYLOSE MHF 10015 P4 is widely used in the daily chemical industry.

TYLOSE MHF 10015 P4 CAS number: 9032-42-2
TYLOSE MHF 10015 P4 Decorative mineral-based plasters
TYLOSE MHF 10015 P4 Tile adhesive, standard
TYLOSE MHF 10015 P4 Cement based trowel compounds
TYLOSE MHF 10015 P4 grout, cement-based
Chemical Properties-soluble in cold water, flocculates at elevated temperatures
Chemical Properties-A white, yellowish-white or grayish-white powder or granules, hygroscopic after drying.
Uses-Water retention aid, thickening agent, protective colloid, suspending agent, binder and stabilizer.
Pharmaceutical Applications-TYLOSE MHF 10015 P4 is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations. It has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.
Safety-TYLOSE MHF 10015 P4 is used as an excipient in various oral and topical pharmaceutical preparations, and is generally regarded as an essentially nontoxic and nonirritant material.
storage-TYLOSE MHF 10015 P4 is hygroscopic and should therefore be stored under dry conditions away from heat.
Regulatory Status-GRAS listed. Included in nonparenteral medicines licensed in Europe (oral suspensions, tablets, and topical preparations).
TYLOSE MHF 10015 P4 is a thickening and gelling agent that comes from cellulose which is used in cleaning solutions and in cosmetics. Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.
1. Product identifier
Product form : Mixture
Product name : Tylose MHF 10015 P4
Product code : (MHEC_M-2)
1.2. Relevant identified uses of the substance or mixture and uses advised against
1.2.1. Relevant identified uses
Use of the substance/mixture : Rheological Additive
Special applications
Coating material
Additive for mortar
1.2.2. Uses advised against
Restrictions on use : There is no information available on applications that are not advised
SECTION 2: Hazards identification
2.1. Classification of the substance or mixture
Classification according to Regulation (EC) No. 1272/2008 [CLP]
Not classified
Adverse physicochemical, human health and environmental effects
No additional information available
2.2. Label elements
Handle in accordance with good industrial hygiene and safety practice.
2.3. Other hazards
Other hazards not contributing to the classification : Dust may form explosive mixture in air.
Physical state : Solid
Appearance : Powder.
Colour : whitish.
Odour : Odourless.
Odour threshold : No data available
pH : 6 - 8 10g/l
Relative evaporation rate (butylacetate=1) : Not specifically applicable
Melting point : Not specifically applicable
Freezing point : Not specifically applicable
Boiling point : Not specifically applicable
Flash point : Not specifically applicable
Auto-ignition temperature : > 170 °C
Decomposition temperature : No data available
Flammability (solid, gas) : No data available
Vapour pressure : Not specifically applicable
Vapour pressure at 50 °C : Not specifically applicable
Relative vapour density at 20 °C : Not specifically applicable
Relative density : Not specifically applicable
Density : 1.1 - 1.5 g/cm³ 20 °C
Solubility : Water: > 10 g/l @ 20°C
Log Pow : < 0
Viscosity, kinematic : Not specifically applicable
Viscosity, dynamic : Not specifically applicable
Explosive properties : Product is not explosive. Dust may form explosive mixture in air.
Tylose MHF 10015 P4
Persistence and degradability Product is biodegradable. Does not affect the functioning of waste-water treatment plants.
In case of loss of large quantities, advice local authorities.
Chemical oxygen demand (COD) < 1500 mg/g
Recommended fields of application

 Tile adhesives, premium Application performance

Consistency development: fast

Final consistency: very high

Sag resistance: very high

Water demand: very high

Water retention: moderate

Cement retardation: moderate

Heat stability: high

Application properties

Tylose MHF 10015 P4 is mainly recommended for premium cement based tile adhesives. It ensures sufficient water retention and gives very good adhesion strength. The special modification increases the thickening effect, improves the workability and leads to outstanding slip resistance and extra-long open time.

Packaging, storage and safety instructions

This Tylose type is supplied in multilayer paper bags with polyethylene intermediate layer and/or in big bags. When kept in clean, dry conditions in its original packing, Tylose can be stored for a long time. During storage a slow loss of viscosity can be measured. Tylose absorbs water from moist air. Once opened, container must be resealed and kept tightly closed. Like all fine particle organic substances, cellulose ethers constitute a dust explosion hazard.

Dust formation and deposits must be kept to a minimum so that no ignitable dust/air mixtures can form. Ignition sources such as naked flames, hot surfaces, sparks and static electricity should be avoided.


TYLOSE MHF 10015 P4
TYLOSE MHF 10015 P4 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MHF 10015 P4 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MHF 10015 P4 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification. TYLOSE MHF 10015 P4 provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, These products, offered under the brand, are highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.These nonionic, water-soluble polymers can thicken, suspend, bind, emulsify, form films, stabilize, disperse, retain water, and provide protective colloid action. They are readily soluble in water and can be used to prepare solutions with a wide range of viscosities. They have outstanding tolerance for dissolved electrolytes. Application range - Tile adhesives - Skim coat - Tile grouts - Repair mortars - Self-leveling flooring compounds - Cement or gypsum-based mortars - Painting - Ceramics - Textile - Detergents Key properties -Improves water retention -Improves adhesive strength -Improves sag resistance -Improve construction efficiency Packaging and storage A. Standard packed in 25 KG per paper plastic composite bag B. Big bags or other special packages are possible on request Weight/20' container: approx. 10 metric tons with pallets, approx. 14 metric tons without pallets Weight/40' container: approx. 24 metric tons with pallets, approx. 26 metric tons without pallets Stored in its original packaging in a dry and place with temperature below 30℃. It is recommended to use SLEO® MHEC within 2 years. Safety notes The data presented above is in accordance with the present state of our knowledge, but doesn’t absolve the user from carefully checking it all immediately on receipt. We reserve the right to alter product constantly within the scope of technical progress or new developments. The recommendations made above should be checked by preliminary trials because of conditions during processing over which we have no control of, especially where other companies' raw materials are also being used. The working mechanism of methyl hydroxyethyl cellulose, MHEC (Mw = 2.5 · 105 g/mol, DSmethyl = 1.81, MShydroxyethyl = 0.15) as water retention agent in cement was investigated. First, the hydrocolloid was characterized and its performance as non-ionic water retention agent was determined employing the filter paper test. Also, water sorption and swelling of individual MHEC fibers under conditions of different humidities were monitored by ESEM imaging. Second, its working mechanism was established. It was found that at low dosages, MHEC achieves water retention by intramolecular sorption of water and concomitant swelling while at higher dosages, MHEC molecules agglomerate into large hydrocolloidal microgel particles (d > 1 μm) which effectively plug the pores in the mortar matrix. MHEC association was evidenced by an exponential increase in solution viscosity as concentration rises, a strong increase in the hydrodynamic diameter of solved MHEC molecules, and a noticeable reduction of surface tension. Related Categories Cellulose, Materials Science, Natural Polymers and Biopolymers, Polymer Science, Polymers More... extent of labeling 0.06-0.50 mol hydroxyethyl per mol cellulose (M.S.) 8 wt. % hydroxyethyl 26 wt. % methoxy 1.3-2.2 mol methyl per mol cellulose (D.S.) surface tension 45-55 dyn/cm, 20 °C, 0.1 wt. % viscosity 15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.) transition temp flocculation range 60-90 °C (0.5 wt. %) storage temp. room temp What is TYLOSE MHF 10015 P4? TYLOSE MHF 10015 P4 is also named as methyl hydroxyethyl cellulose (MHEC). It is a white, grayish-white, or yellowish-white granules.It is a non-ionic cellulose ether derived from the addition of ethylene oxide to methylcellulose. It is produced from a natural renewable polymer such as wood pulp or cotton.TYLOSE MHF 10015 P4 can be used as a highly efficient water retention agent, adhesives and film-forming agent, stabilizer, etc.It is widely used in different industrial applications such as oil drilling, construction, and building, paint and coating, pharmaceutical, etc.TYLOSE MHF 10015 P4 can be modified according to customers’ requirement and still have its good anti-sagging property and good workability after modification. Characteristics of TYLOSE MHF 10015 P4 TYLOSE MHF 10015 P4 has various features. They include: 1. Appearance TYLOSE MHF 10015 P4 can be either white, pale yellow or yellowish-white, or grayish-white. It is also odorless. 2. Solubility TYLOSE MHF 10015 P4 is soluble in water (cold or hot water). Although TYLOSE MHF 10015 P4 is insoluble in the most organic solvent but soluble in a binary organic solvent and organic solvent water system. Its highest concentration depends on the viscosity and its solubility varies with viscosity. The lower the viscosity, the greater the solubility and vice versa. 3. PH stability TYLOSE MHF 10015 P4 is stable within the range of 3.0 – 11.0 and its viscosity is hardly affected but a PH value out of this range will decrease its viscosity. 4. Metabolism TYLOSE MHF 10015 P4 is an inert substance and its odorless. It is widely used in food and medicine applications due to its inability to undergo metabolism. 5. Surface Activity It can be used as a dispersant, protective agent, and emulsifier due to its surface-active function in an aqueous solution. 6. Mildew Resistance In the long term storage, TYLOSE MHF 10015 P4 is a good mildew resistance due to its good viscosity stability.Its mildew resistance capacity is higher than the hydroxyethyl cellulose. 7. Water Retention TYLOSE MHF 10015 P4 serves as an effective water retention agent due to its high viscosity in aqueous solution.Its water retention capacity is greater than the methylcellulose. 8. Ash Content Hot water washing is used in the preparation process of TYLOSE MHF 10015 P4, thereby making the ash content very low. 9. Thermal Gel When the TYLOSE MHF 10015 P4 solution is being heated to a certain temperature, it becomes less transparent with the formation of precipitate and gel but if cooled, it goes back to its original state of solution. Common Uses of TYLOSE MHF 10015 P4 TYLOSE MHF 10015 P4 can be used as: Ø Adhesive Ø Protective colloid Ø Thickening agent Ø Film-forming agent Ø Emulsifier Ø Lubricant Ø Suspending agent Industrial Applications of TYLOSE MHF 10015 P4 TYLOSE MHF 10015 P4 is widely used in different industries, which are: · Polymerization · Ceramic · Cosmetics · Construction · Food and Beverages · Pharmaceuticals · Paint and Coatings · Ink and Oil Drilling Summary TYLOSE MHF 10015 P4 as said earlier is a derivative of methylcellulose. It is a non-ionic cellulose ether produced from the raw material of high purity cotton. Its odorless characteristics and inability to metabolize makes it widely used in food and medicine applications. TYLOSE MHF 10015 P4 water retaining capacity and thickening ability makes it suitable for water-based latex painting, ink and oil drilling, construction materials, etc.As it is widely used in diverse applications, getting TYLOSE MHF 10015 P4 from a reputable TYLOSE MHF 10015 P4 supplier assures you of the best product for personal or industrial use.
TYLOSE MHF 10015 P4
Hydroxyethyl cellulose; MHF 10016 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MHF 10016 P4
Hydroxyethyl cellulose; MHS 150003 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MHF 10016 P4
Tylose MHF 10016 P4 is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa).
When infused as a 6% solution, Tylose MHF 10016 P4 approximates the activity of human albumin.
The larger molecular weights, however, increase Tylose MHF 10016 P4's intravascular residence time as well as its plasma expansion effects relative to albumin.

CAS: 9004-62-0
MF: C29H52O21
EINECS: 618-387-5

Tylose MHF 10016 P4 is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids.
Despite these advantages, Tylose MHF 10016 P4 is quite expensive and also has no oxygen-carrying capacity.
Tylose MHF 10016 P4 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +.

Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali Tylose MHF 10016 P4 with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid.

The role of thickener in the aqueous ink is thickened.
The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink.
Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances.
Tylose MHF 10016 P4 may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Hydroxyethyl cellulose and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000.

Tylose MHF 10016 P4 is a gelling and thickening agent derived from cellulose.
Tylose MHF 10016 P4 is widely used in cosmetics, cleaning solutions, and other household products.
Tylose MHF 10016 P4 and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.
This process is known as hydrophilization.
Tylose MHF 10016 P4 is also used extensively in the oil and gas industry as a drilling mud additive under the name HEC as well in industrial applications, paint and coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers.

Tylose MHF 10016 P4 can be one of the main ingredients in water-based personal lubricants.
Tylose MHF 10016 P4 is also a key ingredient in the formation of large bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble.
Among other similar chemicals, Tylose MHF 10016 P4 is often used as slime (and gunge, in the UK).
Tylose MHF 10016 P4 is a commonly used thickener in paint & coating formulations.
Tylose MHF 10016 P4 thickeners are used in paint & coating formulations to increase the viscosity of the paint and to improve its flow and leveling properties.

Tylose MHF 10016 P4 Chemical Properties
Melting point: 288-290 °C (dec.)
Density: 0.75 g/mL at 25 °C(lit.)
Storage temp.: 2-8°C
Solubility H2O: ≤5 wt. % at 20 °C
Form: powder
Color: Light brown powder
Odor: Odorless
PH: pH(20g/l,25℃) : 5.0~8.0
Water Solubility: almost transparency
Merck: 14,4673
Stability: Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides
InChI: InChI=1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3
InChIKey: CWSZBVAUYPTXTG-UHFFFAOYSA-N
CAS DataBase Reference: 9004-62-0(CAS DataBase Reference)
EPA Substance Registry System: Tylose MHF 10016 P4 (9004-62-0)

Tylose MHF 10016 P4 is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water.
Insoluble in common organic solvents.
Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding.
Different viscosity range of solution can be prepared.
Having exceptionally good salt solubility to electrolyte.

Tylose MHF 10016 P4 is soluble in hot or cold water, and does not precipitate at high temperature or boiling, so it has a wide range of solubility and viscosity characteristics, as well as non-thermal gelling properties.
Tylose MHF 10016 P4 is a non-ionic polymer material , can coexist with a wide range of other water-soluble polymers, surfactants, and salts, and is an excellent colloidal thickener for high-concentration dielectric solutions.
The water retention capacity of Tylose MHF 10016 P4 is twice that of methyl cellulose, and it has better flow regulation; the dispersing ability of Tylose MHF 10016 P4 is comparable to that of methyl cellulose and hydroxypropyl methyl cellulose.
The specific dispersing ability is the worst, but the protective colloid ability is the strongest.
Tylose MHF 10016 P4 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder.

Uses
1. Tylose MHF 10016 P4 is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride.
Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry.
Glazing in ceramic industry and toothpaste binder.
Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent.

2. Used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid.
Also can be used for filtrate reducer of oil well cement.
Cross-linking with the polyvalent metal ions into a gel.

3. As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion.
Tylose MHF 10016 P4 widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides.
There are many uses in oil exploitation and machinery industry.
4. As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc.

Thickener, protective colloid, binder, stabilizer and suspending agent.
Tylose MHF 10016 P4 is a thickener, protective colloid, binder, stabilizer, and suspending agent.
Tylose MHF 10016 P4 is obtained from wood pulp Copyright 2014 Cengage Learning.
Tylose MHF 10016 P4 may not be copied, scanned, or duplicated, in whole or in part.
Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s).
Editorial Review has deemed that any suppressed content does not materially affect the overall learning experience.
Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require it or chemical cotton by treatment with an alkali.

Pharmaceutical Applications
Tylose MHF 10016 P4 is a nonionic, water-soluble polymer widely used in pharmaceutical formulations.
Tylose MHF 10016 P4 is primarily used as a thickening agent in ophthalmic and topical formulations, although it is also used as a binder and film-coating agent for tablets.
Tylose MHF 10016 P4 is present in lubricant preparations for dry eye, contact lens care, and dry mouth.
The concentration of Tylose MHF 10016 P4 used in a formulation is dependent upon the solvent and the molecular weight of the grade.
Tylose MHF 10016 P4 is also widely used in cosmetics.

Production methods
1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give Tylose MHF 10016 P4.
The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour.
Squeezed water containing soda to 1: 2.8, pulverized.
Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle.
Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Tylose MHF 10016 P4 was obtained.
The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging.
Then washed with water, centrifugal dewatering, dryed, milled to obtain Tylose MHF 10016 P4.
Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300.

2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze.
Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into.
In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Tylose MHF 10016 P4.
The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Tylose MHF 10016 P4.

Toxicology
Considered to be non toxic.
Use as a food additive indicates good tolerance of small amounts, but excessive amounts or overuse may bring irritant and /or harmful effects.
Polysaccharides are not substantially absorbed from the gastrointestinal tract but may produce a laxative effect.

Synonyms
Hydroxyethyl cellulose
9004-62-0
Hespan
Cellulose, 2-hydroxyethyl ether
2-Hydroxyethyl cellulose
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
Cellulosize
Cellosize
Natrosol
Cellosize QP
Cellosize WP
Tylose H series
Natrosol LR
Tylose P
Cellosize QP3
OETs
Tylose P-X
Tylose PS-X
Cellosize UT 40
Cellosize WP 09
Tylose P-Z series
Glutofix 600
Natrosol 150L
Natrosol 180HH
Natrosol 180L
Natrosol 240JR
Natrosol 250
Natrosol 250G
Natrosol 250H
Natrosol 250HHP
Natrosol 250HHR
Natrosol 250HR
Natrosol 250HX
Natrosol 250L
Natrosol 250M
Natrosol 250MH
Natrosol 300H
Hercules N 100
Hydroxyethyl-cellulose
Natrosol 250H4R
Cellosize WP 300
Tylose H 20
Fuji hec-BL 20
Caswell No. 487
Natrosol 250 HHR
Cellosize WP 300H
Cellosize WP 400H
Unicel QP 100MH
Tylose H 300
Cellosize QP 1500
Cellosize QP 4400
Cellosize WP 4400
Cellosize WPO 9H17
Unicel QP 300 H
Cellosize 4400H16
Cellosize QP 30000
UNII-12VCE9HR9E
UNII-7Q6P4JN1QT
UNII-B24JYI97VR
UNII-R33S7TK2EP
UNII-X70SE62ZAR
UNII-ZYD53NBL45
Hydroxyethyl cellulose ether
Hydroxyethyl ether cellulose
Hec-Al 5000
Unicel QP 52000 H
Hydroxyethyl cellulose [NF]
UNII-6OX6A5C7B6
UNII-S38J6RZN16
Walocel HT 6.000 PFV
UNII-273FM27VK1
UNII-2Q40985DRM
UNII-I2N4ZF9233
UNII-M825OX60H9
Cellulose 2-hydroxyethyl ether
HSDB 578
SCHEMBL23306563
UNII-8136Y38GY5
UNII-L605B5892V
Cellulose, 2- hydroxyethyl ether
Cellulose, ethylene oxide-grafted
DTXSID60873934
AH 15
BL 15
EPA Pesticide Chemical Code 046201
LS-146657
FT-0627136
J 164
H11622
2-Hydroxyethyl cellulose; Cellulose hydroxyethyl ether
2-O-(2-Hydroxyethyl)-4-O-methylhexopyranosyl-(1->4)-[4-O-methylhexopyranosyl-(1->6)]hexopyranosyl-(1->5)-2,6-anhydro-1-deoxyheptitol
Tylose MHS 150003 P4
Tylose MHS 150003 P4 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +.

CAS NO : 9004-62-0
EC NO :618-387-5

IUPAC NAME
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol

SYNONYMS

Hetastarch
9004-62-0
Hespan
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
Plasmasteril
Pentaspan
Hespander
Onkohas
Voluven
Hespander injection
HAS [German]
Penford 260
Penford 280
Penford 290
Ethylex gum 2020
Penford P 208
Essex gum 1360
Essex 1360
Hetastarch [USAN:BAN]
Pentastarch [USAN:BAN]
O-(2-Hydroxyethyl)starch
Hydroxyathylstarke [German]
2-Hydroxyethyl starch ether
Starch 2-hydroxyethyl ether
Tapioca starch hydroxyethyl ether
ASL 607
DTXSID60873934
VZ36173
LS-146657
FT-0627136
2-O-(2-Hydroxyethyl)-4-O-methylhexopyranosyl-(1->4)-[4-O-methylhexopyranosyl-(1->6)]hexopyranosyl-(1->5)-2,6-anhydro-1-deoxyheptitol
2-hydroxyethylcelluloseether;ah15;aw15(polysaccharide);aw15[polysaccharide];bl15;cellosize;The blood coHydroxyethyl cellulose etherngeals the appearance board;5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
HYPROMELLOSE
Hydroxypropyl Methylcellulose
K100M USP Grade
9004-65-3 Active CAS-RN
Cellulose, 2-hydroxypropyl methyl ether
2-Hydroxypropyl methyl cellulose
2-Hydroxypropyl methyl cellulose ether
2-Hydroxypropyl cellulose methyl ether
Hydroxypropylmethylcellulosum
Isopto alkaline
Isopto plain
Isopto Tears
Methocel E,F,K
Methyl cellulose, propylene glycol ether
Methylhydroxypropylcellulosum
Metolose
Tearisol
Hipromelosa
Hypromellosum
Hydroxypropyl methyl cellulose (464)
cellulose hydroxypropyl methyl ether
cellulose,
2-hydroxypropyl methyl ether
2-hydroxypropyl cellulose methyl ether
2-hydroxypropyl methyl cellulose
hydroxypropyl methylcellulose
hydroxypropylmethyl cellulose
hydroxypropylmethylcellulose
hydroxypropylmethylcellulosum
methyl cellulose,
propylene glycol ether
methyl hydroxypropyl cellulose
methylhydroxypropylcellulose
methylhydroxypropylcellulosum
E464, hydroxypropyl methylcellulose, HPMC
hypromellose(noun)
Hydroxypropyl methylcellulose,


TYLOSE MHS 150003 P4

Thickeners and binders
TYLOSE MHS 150003 P4 is a commonly used cellulose ethers organic water-based ink thickening agent, belongs to a water-soluble non-ionic compound, with good water thickening ability, degraded by oxygen, acid and enzyme, under alkaline conditions can be crosslinked by Cu2 +. Has thermal stability, when heated, does not appear gelation, does not occur precipitation under acidic conditions, the film-forming property is good, the aqueous solution can be made of a transparent film, can be derived from the reaction of alkali cellulose with ethylene oxide, having properties such as thickening, emulsifying, adhesive, suspension, film-forming, maintaining moisture and protectiving colloid. The role of thickener in the aqueous ink is thickened. The viscosity of the ink added a thickening agent increases, can improve the physical and chemical stability of the ink; due to the increased viscosity, rheology of the ink can be controlled at the time of printing; the pigment and filler in ink is not easy to precipitate, increasing the storage stability of the water-based ink.
Thickening agent is a cellulose-based material and (or) polyvinyl alcohol substances. Cellulose substances may be methyl cellulose, ethyl cellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, Hydroxyethyl cellulose and hydroxypropylmethyl cellulose; polyvinyl alcohol material may be an or several species of polyethylene 400, 600, 800, 1000, 1600, 2000, 4000, 6000.

Chemical properties
This product is white to yellowish fibrous or powdery solid, non-toxic, tasteless and soluble in water. Insoluble in common organic solvents. Having properties such as thickening, suspending, adhesive, emulsifying, dispersing, water holding. Different viscosity range of solution can be prepared. Having exceptionally good salt solubility to electrolyte.

Uses
1. TYLOSE MHS 150003 P4 is used for cracking method to extract polymerized dispersing agents such as oil water base gel fracturing fluid, polystyrene and polyvinyl chloride. Also for latex thickening agent in paint industry, hygristor in electronics industry, cement anti-coagulant agent and water retention agent in construction industry. Glazing in ceramic industry and toothpaste binder. Also widely used in many aspects such as printing and dyeing, textile, paper, pharmaceutical, health, food, cigarettes, pesticides and fire extinguishing agent.
2. Used as a water-based drilling fluids, and thickening agent and filtrate reducer of completion fluids, thickening agent has obvious effect on brine drilling fluid. Also can be used for filtrate reducer of oil well cement. Cross-linking with the polyvalent metal ions into a gel.
3. As surfactants, protective colloids, emulsion stabilizers in combination with emulsion such as vinyl chloride, vinyl acetate emulsion, and a tackifier, dispersant, dispersion stabilizer of emulsion. Widely used in many aspects such as coatings, fibers, dyeing, paper, cosmetics, pharmaceuticals, pesticides. There are many uses in oil exploitation and machinery industry.
4. As surfactants, latex thickening agent, protective colloid, oil exploitation fracturing fluid and polystyrene and polyvinyl chloride dispersing agents, etc.
Production methods
1. Alkali cellulose is a natural polymer, each of a fiber-based ring contains three hydroxyl groups, the most active hydroxyl reaction to give Tylose MHS 150003 p4. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, took out to squeeze after half an hour. Squeezed water containing soda to 1: 2.8, pulverized. Pulverized alkali cellulose was added into the reaction kettle, sealed, vacuumized, nitrogen charge, repeated to vacuumize and nitrogen charge to replace atmosphere in the reaction kettle. Precooled the liquid ethylene oxide was pressed into, cooling water was pumped in jacket of reaction kettle, controlled at about 25 ℃ and reacted for 2 h, crude product of Tylose MHS 150003 p4. was obtained. The crude product was washed with alcohol, added acetic acid to adjust pH value to 4-6, added glyoxal to crosslink and aging. Then washed with water, centrifugal dewatering, dryed, milled to obtain Tylose MHS 150003 p4. Raw material consumption (kg/t) linter or low pulp meal 730-780 liquid caustic soda (30%) 2400 ethylene oxide 900 alcohol (95%) 4500 acetic acid 240 Glyoxal (40%) 100-300.
2. The raw material cotton linter or refined pulp meal were immersed in 30% liquid caustic soda, after half an hour took out to squeeze. Squeezed water containing soda to 1: 2.8, pulverized alkali cellulose was added into the reaction kettle, sealed and vacuumized, nitrogen charge, used nitrogen to replace all atmosphere in the reaction kettle,Precooled the liquid ethylene oxide was pressed into. In the cooling, controlled at 25 ℃ and reacted for 2 h, to give the crude product of crude Tylose MHS 150003 p4. The crude product was washed with ethanol and acetic acid was added to adjust the pH value to 4-6. added glyoxal to crosslink and aging, washed with water fast, finally centrifugal dehydration, dried, milled, obtained low salt Tylose MHS 150003 p4.
Description
Hetastarch, another nonproteinaceous colloid, is a complex mixture of ethoxylated amylopectins ranging in molecular weight from 10 to 1,000 kDa (average molecular weight, ~450 kDa). When infused as a 6% solution, hetastarch approximates the activity of human albumin. The larger molecular weights, however, increase its intravascular residence time as well as its plasma expansion effects relative to albumin.
Hetastarch is synthetically produced, so it is degraded more slowly and is less antigenic than other colloids. Despite these advantages, hetastarch is quite expensive and also has no oxygen-carrying capacity.
Chemical Properties
light yellow powder
Chemical Properties
TYLOSE MHS 150003 P4 occurs as a white, yellowish-white or grayish-white, odorless and tasteless, hygroscopic powder.
Uses
TYLOSE MHS 150003 P4 is a thickener, protective colloid, binder, stabilizer, and suspending agent. It is obtained from wood pulp Copyright 2014 Cengage Learning. All Rights Reserved. May not be copied, scanned, or duplicated, in whole or in part. Due to electronic rights, some third party content may be suppressed from the eBook and/or eChapter(s). Editorial Review has deemed that any suppressed content does not materially affect the overall learning experience. Cengage Learning reserves the right to remove additional content at any time if subsequent rights restrictions require it. or chemical cotton by treatment with an alkali.
Pharmaceutical Applications
TYLOSE MHS 150003 P4 is a nonionic, water-soluble polymer widely used in pharmaceutical formulations. It is primarily used as a thickening agent in ophthalmic and topical formulations, although it is also used as a binder and film-coating agent for tablets.It is present in lubricant preparations for dry eye, contact lens care, and dry mouth.
The concentration of TYLOSE MHS 150003 P4 used in a formulation is dependent upon the solvent and the molecular weight of the grade.
TYLOSE MHS 150003 P4 is also widely used in cosmetics.
storage
TYLOSE MHS 150003 P4 powder is a stable though hygroscopic material.
Aqueous solutions of hydroxyethyl cellulose are relatively stable at pH 2–12 with the viscosity of solutions being largely unaffected. However, solutions are less stable below pH 5 owing to hydrolysis. At high pH, oxidation may occur.
Increasing the temperature reduces the viscosity of aqueous TYLOSE MHS 150003 P4 solutions. However, on cooling, the original viscosity is restored. Solutions may be subjected to freeze–thawing, high-temperature storage, or boiling without precipitation or gelation occurring.
TYLOSE MHS 150003 P4 is subject to enzymatic degradation, with consequent loss in viscosity of its solutions. Enzymes that catalyze this degradation are produced by many bacteria and fungi present in the environment. For prolonged storage, an antimicrobial preservative should therefore be added to aqueous solutions. Aqueous solutions of TYLOSE MHS 150003 P4 may also be sterilized by autoclaving.
TYLOSE MHS 150003 P4 powder should be stored in a well-closed container, in a cool, dry place.

Incompatibilities
TYLOSE MHS 150003 P4 is insoluble in most organic solvents. It is incompatible with zein and partially compatible with the following water-soluble compounds: casein; gelatin; methylcellulose; polyvinyl alcohol, and starch.
TYLOSE MHS 150003 P4 can be used with a wide variety of watersoluble antimicrobial preservatives. However, sodium pentachlorophenate produces an immediate increase in viscosity when added to hydroxyethyl cellulose solutions.
TYLOSE MHS 150003 P4 has good tolerance for dissolved electrolytes, although it may be salted out of solution when mixed with certain salt solutions. For example, the following salt solutions will precipitate a 10% w/v solution of Cellosize WP-09 and a 2% w/v solution of Cellosize WP-4400: sodium carbonate 50% and saturated solutions of aluminum sulfate; ammonium sulfate; chromic sulfate; disodium phosphate; magnesium sulfate; potassium ferrocyanide; sodium sulfate; sodium sulfite; sodium thiosulfate; and zinc sulfate.
Natrosol is soluble in most 10% salt solutions, excluding sodium carbonate and sodium sulfate, and many 50% salt solutions with the exception of the following: aluminum sulfate; ammonium sulfate; diammonium phosphate; disodium phosphate; ferric chloride; magnesium sulfate; potassium ferrocyanide; sodium metaborate; sodium nitrate; sodium sulfite; trisodium phosphate; and zinc sulfate. Natrosol 150 is generally more tolerant of dissolved salts than is Natrosol 250.
TYLOSE MHS 150003 P4 is also incompatible with certain fluorescent dyes or optical brighteners, and certain quaternary disinfectants which will increase the viscosity of aqueous solutions.
Information on basic physical and chemical properties
TYLOSE MHS 150003 P4 Physical state : Solid
TYLOSE MHS 150003 P4 Appearance : Powder.
TYLOSE MHS 150003 P4 Colour : whitish.
TYLOSE MHS 150003 P4 Odour : Odourless.
TYLOSE MHS 150003 P4 Odour threshold : No data available
TYLOSE MHS 150003 P4 pH : 6 - 8 10g/l
TYLOSE MHS 150003 P4 Relative evaporation rate (butylacetate=1) : Not specifically applicable
TYLOSE MHS 150003 P4 Melting point : Not specifically applicable
TYLOSE MHS 150003 P4 Freezing point : Not specifically applicable
TYLOSE MHS 150003 P4 Boiling point : Not specifically applicable
TYLOSE MHS 150003 P4 Flash point : Not specifically applicable
TYLOSE MHS 150003 P4 Auto-ignition temperature : > 170 °C
TYLOSE MHS 150003 P4 Decomposition temperature : No data available
TYLOSE MHS 150003 P4 Flammability (solid, gas) : No data available
TYLOSE MHS 150003 P4 Vapour pressure : Not specifically applicable
TYLOSE MHS 150003 P4 Vapour pressure at 50 °C : Not specifically applicable
TYLOSE MHS 150003 P4 Relative vapour density at 20 °C : Not specifically applicable
TYLOSE MHS 150003 P4 Relative density : Not specifically applicable
TYLOSE MHS 150003 P4 Density : 1.1 - 1.5 g/cm³ 20 °C
TYLOSE MHS 150003 P4 Solubility : Water: > 10 g/l @ 20°C
TYLOSE MHS 150003 P4 Log Pow : < 0
TYLOSE MHS 150003 P4 Viscosity, kinematic : Not specifically applicable
TYLOSE MHS 150003 P4 Viscosity, dynamic : Not specifically applicable
TYLOSE MHS 150003 P4 Explosive properties : Product is not explosive. Dust may form explosive mixture in air.
TYLOSE MHS 150003 P4 Oxidising properties : No data available
TYLOSE MHS 150003 P4 Lower explosive limit (LEL) : 30 g/m³
TYLOSE MHS 150003 P4 Minimum ignition energy : > 10 mJ
TYLOSE MHS 150003 P4 Bulk density : 200 - 600 g/l
TYLOSE MHS 150003 P4 Conbustion class : 5
TYLOSE MHS 150003 P4 Smst explosion category : ST1
TYLOSE MHS 150003 P4 KSt : < 200 bar*m/s

Tylose MHS 150003 P4
Persistence and degradability Product is biodegradable. Does not affect the functioning of waste-water treatment plants.
In case of loss of large quantities, advice local authorities.
Chemical oxygen demand (COD) < 1500 mg/g
Tylose MHS 150003 P4
Log Pow < 0
Bioaccumulative potential Not potentially bioaccumulable

Tylose MHS 150003 P4 is a water-soluble, non-ionic, highly etherified, modified methyl hydroxyethyl cellulose powder. It provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. This grade of methyl hydroxyethyl cellulose (MHEC) is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters.
Recommended fields of application

 Plasters, gypsum based Thin layer plasters, gypsum based Gypsum-Lime-Plasters Tile adhesives

Application performance

Consistency development: very fast

Water retention: very high

Final consistency: moderate

Influence on cement hydration: moderate

Sag resistance: moderate

Heat stability: high

Water demand: high

Packaging, Storage, Safety instructions Packaging, Storage, Safety instructions Like all fine-particle organic substances, cellulose ethers constitute a dust explosion hazard. Dust formation and deposits must be kept to a minimum so that no ignitable dust/air mixtures can form. Ignition sources such as naked flames, hot surfaces, sparks and static electricity should be avoided. Tylose starts to decompose at about 200°C. Its ignition temperature is >360°C.

Tylose burns easily and the fire may spread. When stored in closed containers, or in its original packaging in a dry place. at room temperature, Tylose can be kept for a long time. In the case of high viscosity grades, a slow loss of viscosity can be measured after lengthy storage (>1 year). Tylose absorbs water from moist air. Once opened, container must be resealed and kept tightly closed. This Tylose-type is supplied in multi-ply paper bags with polyethylene intermediate layer and/or in big bags.
Application Performance
Consistent development of Tylose MHS 150009 P4: fast Water retention: very high
Final consistency of Tylose MHS 150009 P4: moderate Effect on cement hydration: medium
Tylose MHS 150009 P4 sag resistance: medium Heat stability: high
Water demand: high
Packaging, Storage, Safety instructions Packaging, Storage, Safety instructions Tylose MHS 150009 P4
Like all fine organic matter, Tylose MHS 150009 P4 poses a dust explosion hazard. Dust formation
Deposits should be kept to a minimum so that no sediment / air mixture can form. Sources of ignition
naked flames, hot surfaces, sparks and static electricity should be avoided. Tylose also begins to decompose
approx. 200 ° C. Ignition temperature> 360 ° C. Tylose MHS 150009 P4 easily burns and a fire could occur.
When Tylose MHS 150009 P4 is stored in closed containers or in its original packaging in a dry place at room temperature,
should be stored for a long time. In case of high viscosity grades, a slow loss of viscosity
long-term storage (> 1 year). Tylose absorbs water from moist air. After opening, the container should be closed and
it is kept tightly closed.
Tylose MHS 150009 P4 Effect on cement hydration: medium
Tylose MHS 150009 P4 Heat stability: high
Tylose MHS 150009 P4 Recommended Application Areas
Tylose MHS 150009 P4 Used in building materials.
Tylose MHS 150009 P4 is used as block flooring adhesive.
Tylose MHS 150009 P4 Used as plaster mounting binders.
Tylose MHS 150009 P4 Used in gypsum spray plaster.
TYLOSE MHS ​​150009 P4 Usage Areas:
Gypsum-based hand and machine plasters
Gypsum-based satin (thin layer) plaster
Gypsum-Lime based plasters
Tile adhesives
Gypsum Based Hand and Machine Plasters
Product Name Chemical Description Uses
TYLOSE MH 10.001 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 10.000 mPas Decorative mineral based plasters, Smooth block adhesives, Tile adhesives, Exterior coating and insulation systems
TYLOSE MH 10.007 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 10.000 mPas Decorative mineral based plasters, Smooth block adhesives, Tile adhesives, Exterior coating and insulation systems
TYLOSE MH 15.000 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 15.000 mPas Ready-mixed concrete joint fillers, Tile adhesives Exterior coating and insulation systems, Gypsum-based joint compounds, Insulation Plasters
TYLOSE MH 15.002 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 15.000 mPas Cement-lime based plaster, Gypsum-Lime based plaster, Smooth block adhesive, Exterior Coating and insulation systems, thin layer plaster, Repair plaster
TYLOSE MH 2.000 YP2 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 2.000 mPas Cement based screed plaster, Repair plasters, Cement based plasters
TYLOSE MH 30.000 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 30.000 mPas Cement Based plaster compounds, Masonry Mortars, Ready mixed concrete joint filler, Cement based paints
TYLOSE MH 6.000 YP4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 6.000 mPas Cement based screed plaster, Cement based Plaster compounds Decorative surface coatings
TYLOSE MH 60.004 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 60.000 mPas. Tile adhesives, cement-based hand plasters, cement-lime-based plasters, gypsum-based plasters.
TYLOSE MH 60.027 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 60.000 mPas. Tile adhesives, cement-based hand plasters, cement-lime-based plasters, gypsum-based plasters.
TYLOSE MH 60.028 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 60.000 mPas. Tile adhesives, cement-based hand plasters, cement-lime-based plasters, gypsum-based plasters and sheathing products.
TYLOSE MH 150009 P4 Methyl Hydroxy Ethyl Cellulose.
TYLOSE MH 150009 P4 Physical State: Free Powder
TYLOSE MH 150009 P4 Humidity: ≤ 6%
TYLOSE MH 150009 P4 NaCl content: ≤ 1.5%
TYLOSE MH 150009 P4 Grain size: <100μm: min. 90%
TYLOSE MH 150009 P4 Grain size: <63μm: min. 65%
TYLOSE MHS 150003 P4
Hydroxyethyl cellulose; MHS 150009 P4; Cellulose, 2 - hydroxyethyl ether; hydroxyethyl cellulose ;Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
TYLOSE MHS 150009 P4

Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder.

CAS NO 9004-62-0
SYNONYMS:
2-Hydroxyethyl cellulose;2-Hydroxyethyl cellulose ether;AH 15;AW 15 (Polysaccharide);BL 15;Caswell No. 487;Cellosize4400H16;Cellosize QP;Cellosize QP 1500;Cellosize QP 30000;Cellosize QP 4400;Cellosize QP3;Cellosize UT 4;Cellosize WP;Cellosize WP 09;Cellosize WP 300;Cellosize WP 300H;Cellosize WP 400H;Cellosize WP 4400;Cellosize WPO 9H17;Cellulose 2-hydroxyethyl ether;Cellulose hydroxyethyl ether;Cellulose hydroxyethylate;Cellulose, 2-hydroxyethyl ether;Cellulose, ethylene oxide-grafted;Cellulosize;EPA Pesticide Chemical Code 046201;Fuji hec-BL 20;Glutofix 600;HEC;Hec-Al 5000;Hespan;HSDB 578;Hydroxyethyl cellulose;Hydroxyethyl cellulose ether;Hydroxyethyl ether cellulos;Hydroxyethylcellulose;Hyetellos;Natrosol;Natrosol 150L;Natrosol 180HH;Natrosol 180L;Natrosol 250;Natrosol 250 HHR;Natrosol 250G;Natrosol 250H;Natrosol 250H4R;Natrosol 250HHP;Natrosol 250HHR;Natrosol 250HR;Natrosol 250HX;Natrosol 250L;Natrosol 250M;Natrosol 250MH;Natrosol 300H;Natrosol LR;OETs;Oxirane, polymer with cellulose;Tylose H 20;Tylose300;Tylose H series;tylose P;Tylose P-X;Tylose P-Z series;Tylose PS-X;Unicel QP 100MH;Unicel QP 300 H;Unicel QP 52000 H;UNII-12VCE9HR9E;UNII-2Q40985DRM;UNII-6OX6A5C7B6;UNII-7Q6P4JN1QT;UNII-8136Y38GY5;UNII-B24JYI97VR;UNII-I2N4ZF9233;UNII-L605B5892V;UNII-M825OX60H9;UNII-S38J6RZN16;UNII-T4V6TWG28D;UNII-X70SE62ZA;UNII-ZYD53NBL45;Walocel HT 6.000 PFV;Tylose MHS 150009 P4
Hetastarch;9004-62-0;5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol;DTXSID60873934;VZ36173;FT-0627136;2-O-(2-Hydroxyethyl)-4-O-methylhexopyranosyl-(1->4)-[4-O-methylhexopyranosyl-(1->6)]hexopyranosyl-(1->5)-2,6-anhydro-1-deoxyheptitol
2-hydroxyethylcelluloseether
ah15
aw15(polysaccharide)
aw15[polysaccharide]
bl15
cellosize
The blood coHydroxyethyl cellulose etherngeals the appearance board
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol
2-HYDROXYETHYL CELLULOSE
Natrosol L 250
hydrdoxyethyl cellulose
2-HYDROXYETHYL CELLULOSE, AVERAGE MV CA. 90,000
2-HYDROXYETHYL CELLULOSE, AVERAGE MV CA. 1,300,000
HYDROXYETHYL-CELLULOSE 90'000-105'000
2-HYDROXYETHYL CELLULOSE, AVERAGE MV CA. 720,000
HydroxyethylCelluloseHighViscosity(200)
HydroxyethylCellulose(Hec),Cas
HYDROXYETHYL CELLULOSE (HEC)
NATROSOL(R)250
hydroxyethy cellulolse
HYDROXYETHYL CELLULOSE: 200-300CPS (2% IN WATER)
Hydroxyethyl Cellulose (200-300mPa.s, 2% in Water at 20deg C)
Hydroxyethyl Cellulose (4,500-6,500mPa.s, 2% in Water at 25deg C)
Hydroxyethyl Cellulose (800-1,500mPa.s, 2% in Water at 20deg C)
HYDROXYETHYLCELLULOSE,100CPS,NF
HYDROXYETHYLCELLULOSE,2000CPS,NF
HYDROXYETHYLCELLULOSE,3,400CPS
HYDROXYETHYLCELLULOSE,5,000CPS
HYDROXYETHYLCELLULOSE,5,000CPS,NF
2-Hydroxyethyl cellulose, hydrophobically modified
cellosize4400h16
cellosizeqp
cellosizeqp1500
cellosizeqp3
cellosizeqp30000
cellosizeqp4400
cellosizeut40
cellosizewp
cellosizewp09
cellosizewp300
cellosizewp300h
cellosizewp400h
cellosizewp4400
cellosizewpo9h17
cellulose,ethyleneoxide-grafted
cellulosehydroxyethylate
fujihec-bl20
glutofix600
hec-al5000
herculesn100
hespan
hetastarch
hydroxyethylethercellulose
j164
natrosol
natrosol150l
natrosol180hh
natrosol180l


Tylose MHS 150009 P4

DOCUMENTS

Tylose MHS 150009 P4 is a water-soluble, non-ionic, highly etherified, modified methyl hydroxyethyl cellulose powder.Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. This grade Tylose MHS 150009 P4 is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters.
 water-soluble cellulose ethers under the Tylose® trade name - including methyl hydroxyethyl cellulose (MHEC), methyl hydroxypropyl cellulose (MHPC), and hydroxyethyl cellulose (HEC) - for applications such as construction and ceramic coatings & paints.
Tylose MHS 150009 P4
Technical Data Sheet
O OH CH, CH2, CH3
Product properties Product properties of Tylose MHS 150009 P4 
Constitution: Methylhydroxyethyl cellulose modified
Appearance of Tylose MHS 150009 P4 : powder Delayed solubility: no
Etherification of Tylose MHS 150009 P4 : high etherification Thickening effect: moderate
Particle size of Tylose MHS 150009 P4 : fine powder Level of viscosity: 150000 mPas
according to Höppler
Product specification Product specification of Tylose MHS 150009 P4 Recommended fields of application Recommended fields of application
Moisture of Tylose MHS 150009 P4 : ≤ 6 %
Content of NaCl of Tylose MHS 150009 P4 : ≤ 1.5 %
Particle size of Tylose MHS 150009 P4 : <125µm: min. 85%
Particle size of Tylose MHS 150009 P4 : <100µm: min. 70%
Viscosity of Tylose MHS 150009 P4 : 5600 - 8000 mPas
Brookfield RV,20rpM, 1.0%,20°C,20° GH
Plasters, gypsum based
Thin layer plasters, gypsum based
Gypsum-Lime-Plasters
Tile adhesives
Product properties 
Constitution:Methyl hydroxyethyl cellulose modified
Appearance:powder
Etherification:high
Particle size:fine powder
Delayed solubility:no
Level of viscosity:
according to Höppler 150000 mPa•s
Tylose® MHS grades - water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose 

Application performance 
Building materials 
Consistency development:very fast
Final consistency:moderate
Sag resistance:moderate
Water demand:high
Water retention:very high
Influence on cement hydration:moderate
Heat stability:high

Tylose MHS 150009 P4
Technical Data Sheet
Application performance Application performance
Consistency development of Tylose MHS 150009 P4 : fast Water retention: very high
Final consistency of Tylose MHS 150009 P4 : moderate Influence on cement hydration: moderate
Sag resistance of Tylose MHS 150009 P4 : moderate Heat stability: high
Water demand: high
Packaging, Storage, Safety instructions Packaging, Storage, Safety instructions of Tylose MHS 150009 P4 
Like all fine-particle organic substances, of Tylose MHS 150009 P4 constitute a dust explosion hazard. Dust formation
and deposits must be kept to a minimum so that no ignitable dust/air mixtures can form. Ignition sources such
as naked flames, hot surfaces, sparks and static electricity should be avoided. Tylose starts to decompose at
about 200°C. Its ignition temperature is >360°C. of Tylose MHS 150009 P4 burns easily and the fire may spread.
When stored in closed containers, or in its original packaging in a dry place at room temperature, of Tylose MHS 150009 P4 can
be kept for a long time. In the case of high viscosity grades, a slow loss of viscosity can be measured after
lengthy storage (>1 year). Tylose absorbs water from moist air. Once opened, container must be resealed and
kept tightly closed.
 of Tylose MHS 150009 P4 is supplied in multi-ply paper bags with polyethylene intermediate layer and/or in big bags. 

Tylose MHS 150009 P4
Product Properties
Constitution: Methyl hydroxyethyl cellulose modified
Appearance: powder
Etherification: high
Particle size: fine powder
Delayed solubility: no
Level of viscosity:
according to Höppler 15000 mPa•s
Tylose® MHS grades – water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose

Application Performance
Building Materials
Consistency development: very fast
Final consistency: moderate
Sag resistance: moderate
Water demand: high
Water retention: very high
Influence on cement hydration: moderate
Heat stability: high
Recommended Fields Of Application
Building Materials
Block laying adhesive
Gypsum mounting binder
Gypsum spray plaster
Nomenclature Information
Type of ether Viscosity level Chemical refinement
M Methyl 60000 
The viscosity level is based on
Hoeppler: 2%
solution of the
commercial product
with 5% moisture
content, 20ºC,
20º dH
(German hardness)

Y Delayed solubility products
H Hydroxyethyl 30000 K Readily soluble granules
O Hydroxypropyl 15000 N non-delayed solubility products
A Allyl 10000 (only for Tylose H grades) *
X Hydrophobe 6000 
etherification 4000 Degree of particle size
2000 Types of granules:
Degree of 1000 G4 Granules (< 500 μm)
B etherification 300 G6 Granules (< 400 μm)
F Special higher 200 G6 Granules (< 400 μm)
S degrees of . Powder types:
T etherification, . P2 Powder (< 180 μm)
depending on the . P3 Fine Powder (< 125 μm)
individual type of 01 P4 Fine powder (< 125 μm)
ether 02 P6 Ultra fine powder (< 100 μm)

Tylose MHS grades
Grades Knowledge Base
Tylose MHS 10012 P6 
Tylose MHS 30024 P4 
Tylose MHS 30027 P6 
Tylose MHS 60000 YP4 
Tylose MHS 100005 P3 
Tylose MHS 100006 P3 
Tylose MHS 150009 P4 
Tylose MHS 150012 P4 
Tylose MHS 300000 P4 ,


Gypsum Based Hand and Machine Plasters
Product Name Chemical Description Usage Areas
TYLOSE MH 10.001 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 10.000 mPas Decorative mineral based plasters, Smooth block adhesives, Tile adhesives, Exterior coating and insulation systems
TYLOSE MH 10.007 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 10,000 mPas Decorative mineral based plasters, Smooth block adhesives, Tile adhesives, Exterior coating and insulation systems
TYLOSE MH 15.000 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 15.000 mPas Ready-mixed concrete joint fillers, Tile adhesives External coating and insulation systems, Gypsum-based joint compounds, Insulation Plasters
TYLOSE MH 15.002 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 15.000 mPas Cement-lime-based plasters, Gypsum-Lime-based plasters, Smooth block adhesives, Exterior Coating and insulation systems, thin layer plasters, Repair plasters
TYLOSE MH 2.000 YP2 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 2.000 mPas Cement-based screed plaster, Repair plasters, Cement-based plasters
TYLOSE MH 30.000 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 30.000 mPas Cement Based plastering compounds, Masonry Mortars, Ready-mixed concrete grouting, Cement-based paints
TYLOSE MH 6.000 YP4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 6.000 mPas Cement-based screed plaster, Cement-based Plastering compounds Decorative surface coatings
TYLOSE MH 60.004 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 60.000 mPas. Tile adhesives, cement based hand applied plasters, cement lime based plasters, gypsum based plasters.
TYLOSE MH 60.027 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 60.000 mPas. Tile adhesives, cement based hand applied plasters, cement lime based plasters, gypsum based plasters.
TYLOSE MH 60.028 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 60.000 mPas. Tile adhesives, cement based hand applied plasters, cement lime based plasters, gypsum based plasters and jacketing products.

TYLOSE MHS 150009 P4

DOCUMENTS
Tylose MHS 150009 P4 

 Tylose MHS 150009 P4 is a water-soluble. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. Tylose MHS 150009 P4 is a water-soluble, non-ionic, highly etherified, modified methyl hydroxyethyl cellulose powder.Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. This grade Tylose MHS 150009 P4 is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters.
water-soluble cellulose ethers under the Tylose trade name - including methyl hydroxyethyl cellulose (MHEC), methyl hydroxypropyl cellulose (MHPC), and hydroxyethyl cellulose (HEC) - for applications such as construction and ceramic coatings & paints. Tylose MHS 150009 P4 of methyl hydroxyethyl cellulose (MHEC) is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades – water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose.Tylose MHS 150009 P4 is a water-soluble. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. This grade Tylose MHS 150009 P4 of methyl hydroxyethyl cellulose (MHEC) is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades – water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose. Tylose MHS 150009 P4 is a water-soluble, non-ionic, highly etherified, modified methyl hydroxyethyl cellulose powder.Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. This grade Tylose MHS 150009 P4 is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters..

 Tylose MHS 150009 P4 Technical Data Sheet

MHS 150003 P4O OH CH, CH2, CH3
Product properties Product properties of Tylose MHS 150009 P4
Constitution: Methylhydroxyethyl cellulose modified
Appearance of Tylose MHS 150009 P4 : powder Delayed solubility: no
Etherification of Tylose MHS 150009 P4 : high etherification Thickening effect: moderate
Particle size of Tylose MHS 150009 P4 : fine powder Level of viscosity: 150000 mPas according to Höppler
Product specification Product specification of Tylose MHS 150009 P4 Recommended fields of application Recommended fields of application
Moisture of Tylose MHS 150009 P4 : ≤ 6 %
Content of NaCl of Tylose MHS 150009 P4 : ≤ 1.5 %
Particle size of Tylose MHS 150009 P4 : <125µm: min. 85%
Particle size of Tylose MHS 150009 P4 : <100µm: min. 70%
Viscosity of Tylose MHS 150009 P4 : 5600 - 8000 mPas
Brookfield RV,20rpM, 1.0%,20°C,20° GH
Tylose MHS 150009 P4 is used as Plasters, gypsum based
Tylose MHS 150009 P4 is used as Thin layer plasters, gypsum based
Tylose MHS 150009 P4 is used as Gypsum-Lime-Plasters
Tylose MHS 150009 P4 is used as Tile adhesives.

Product properties 
Constitution:Methyl hydroxyethyl cellulose modified
Appearance:powder
Etherification:high
Particle size:fine powder
Delayed solubility:no
Level of viscosity:
according to Höppler 150000 mPa•s
Tylose MHS grades - water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose
 
Tylose MHS 150009 P4 of methyl hydroxyethyl cellulose (MHEC) is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades – water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration Tylose MHS 150009 P4 is a water-soluble. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention, and heat stability, and moderate sag resistance and influence on cement hydration. This grade Tylose MHS 150009 P4 of methyl hydroxyethyl cellulose (MHEC) is ideal for use in block laying adhesives and gypsum mounting binders and spray plasters.
Application performance of 
Building materials 
Consistency development:very fast
Final consistency:moderate
Sag resistance:moderate
Water demand:high
Water retention:very high
Influence on cement hydration:moderate
Heat stability:high
 
 
Tylose MHS 150003 P4
Technical Data Sheet
Application performance Application performance
Consistency development of Tylose MHS 150009 P4 : fast Water retention: very high
Final consistency of Tylose MHS 150009 P4 : moderate Influence on cement hydration: moderate
Sag resistance of Tylose MHS 150009 P4 : moderate Heat stability: high
Water demand of Tylose MHS 150009 P4 : high

Packaging, Storage, Safety instructions of Tylose MHS 150009 P4

Like all fine-particle organic substances, of Tylose MHS 150009 P4 constitute a dust explosion hazard. Dust formation and deposits must be kept to a minimum so that no ignitable dust/air mixtures can form. Ignition sources such as naked flames, hot surfaces, sparks and static electricity should be avoided. Tylose starts to decompose at about 200°C. Its ignition temperature is >360°C. of Tylose MHS 150009 P4 burns easily and the fire may spread. When stored in closed containers, or in its original packaging in a dry place at room temperature, of Tylose MHS 150009 P4 can be kept for a long time. In the case of high viscosity grades, a slow loss of viscosity can be measured after lengthy storage (>1 year). Tylose absorbs water from moist air. Once opened, container must be resealed and kept tightly closed. of Tylose MHS 150009 P4 is supplied in multi-ply paper bags with polyethylene intermediate layer and/or in big bags.
 
TYLOSE MHS 150009 P4 
Tylose MHS 150009 P4 
Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention and heat stability, and an effect on moderate sag resistance and cement hydration. Consisting of methyl hydroxyethyl cellulose (MHEC), this Tylose MHS 150009 P4 grade is ideal for use in block floor adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades - water soluble, nonionic, highly etherified methyl hydroxyethyl cellulose. Tylose MHS 150009 P4 Like all fine organic matter, Tylose MHS 150009 P4 poses a dust explosion hazard. Deposits should be kept to a minimum so that no sediment / air mixture is formed. Tylose MHS 150009 P4 Sources of ignition: bare flames, hot surfaces, sparks and static electricity should be avoided. Tylose MHS 150009 P4 begins to decompose about 200 ° C. Ignition temperature> 360 ° C. Tylose MHS 150009 P4 easily burns and a fire could occur. Tylose MHS 150009 P4 should be stored for a long time when stored in closed containers or Tylose MHS 150009 P4 in its original packaging in a dry place at room temperature. This type of Tylose MHS 150009 P4 is ideal for use in block flooring adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 for applications such as construction and ceramic coatings and paints, including water soluble cellulose ethers - methyl hydroxyethyl cellulose (MHEC), methyl hydroxypropyl cellulose (MHPC) and hydroxyethyl cellulose (HEC) under the trade name Tylose MHS 150009 P4 .
Tylose MHS 150009 P4 
Technical data sheet Tylose MHS 150009 P4 OOH CH, CH2, CH3
Tylose MHS 150009 P4 Product features
Constitution: Methylhydroxyethyl cellulose modified
The appearance of Tylose MHS 150009 P4 : powder Delayed resolution: no
Tylose MHS 150009 P4 : high etherification Thickening effect: medium
Tylose MHS 150009 P4 particle size: fine powder Viscosity level: 150000 mPas
Moisture of Tylose MHS 150009 P4 : 6%
NaCl content of Tylose MHS 150009 P4 : ≤ 1.5%
Particle size of Tylose MHS 150009 P4 : <125um: min. 85%
Particle size of Tylose MHS 150009 P4 : <100um: min. 70%
Viscosity of Tylose MHS 150009 P4 : 5600-8000 mPas
Tylose MHS 150009 P4 Brookfield RV, 20rpM, 1.0%, 20 ° C, 20 ° GH
Tylose MHS 150009 P4 Used in gypsum based plasters.
Tylose MHS 150009 P4 Thin layer plasters are used based on gypsum. Used in Tylose MHS 150009 P4 Gypsum-Lime-Plasters.
Tylose MHS 150009 P4 is used in tile adhesives.
 
 Tylose MHS 150009 P4 
Technical data sheet
Application performance Application performance
Consistent development of Tylose MHS 150009 P4 : fast Water retention: very high
Final consistency of Tylose MHS 150009 P4 : moderate Effect on cement hydration: medium
Tylose MHS 150009 P4 sag resistance: medium Heat stability: high
Tylose MHS 150009 P4 Water demand: high

Tylose MHS 150009 P4 long-term storage (> 1 year). Tylose absorbs water from moist air. Tylose MHS 150009 P4 After opening, the container should be closed and kept tightly closed. Tylose MHS 150009 P4 is supplied in multi-layer paper bags with a polyethylene interlayer and / or big bags. Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention and heat stability, and an effect on moderate sag resistance and cement hydration. Consisting of methyl hydroxyethyl cellulose (MHEC), this Tylose MHS 150009 P4 grade is ideal for use in block flooring adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades - water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose..Tylose MHS 150009 P4 Application Performance.Tylose MHS 150009 P4 Used in building materials. Consistency improvement of Tylose MHS 150009 P4 : very fast Tylose MHS 150009 P4 Final consistency: medium.Tylose Tylose MHS 150009 P4 Packaging, Storage, Safety instructions Packaging, Storage, Safety instructions Tylose MHS 150009 P4 
Tylose MHS 150009 P4 Like all fine organic matter, Tylose MHS 150009 P4 poses a dust explosion hazard. Deposits should be kept to a minimum so that no sediment / air mixture is formed. Tylose MHS 150009 P4 Sources of ignition: bare flames, hot surfaces, sparks and static electricity should be avoided. Tylose MHS 150009 P4 begins to decompose about 200 ° C. Ignition temperature> 360 ° C. Tylose MHS 150009 P4 easily burns and a fire could occur. Tylose MHS 150009 P4 should be stored for a long time when stored in closed containers or Tylose MHS 150009 P4 in its original packaging in a dry place at room temperature. In case of high viscosity grades, a slow loss of viscosity
 
Tylose MHS 150009 P4 Application Performance.Tylose MHS 150009 P4 Used in building materials. Consistency improvement of Tylose MHS 150009 P4 : very fast Tylose MHS 150009 P4 Final consistency: medium. Deposits should be kept to a minimum so that no sediment / air mixture is formed. Tylose MHS 150009 P4 Sources of ignition: bare flames, hot surfaces, sparks and static electricity should be avoided. Tylose MHS 150009 P4 begins to decompose about 200 ° C. Ignition temperature> 360 ° C. Tylose MHS 150009 P4 easily burns and a fire could occur. Tylose MHS 150009 P4 should be stored for a long time when stored in closed containers or Tylose MHS 150009 P4 in its original packaging in a dry place at room temperature. This type of Tylose MHS 150009 P4 is ideal for use in block flooring adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 for applications such as construction and ceramic coatings and paints, including water soluble cellulose ethers - methyl hydroxyethyl cellulose (MHEC), methyl hydroxypropyl cellulose (MHPC) and hydroxyethyl cellulose (HEC) under the trade name Tylose MHS 150009 P4 . Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention and heat stability, and an effect on moderate sag resistance and cement hydration. Consisting of methyl hydroxyethyl cellulose (MHEC), this Tylose MHS 150009 P4 grade is ideal for use in block floor adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades - water soluble, nonionic, highly etherified methyl hydroxyethyl cellulose. Tylose MHS 150009 P4 Like all fine organic matter, Tylose MHS 150009 P4 poses a dust explosion hazard. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention and heat stability, and an effect on moderate sag resistance and cement hydration. Consisting of methyl hydroxyethyl cellulose (MHEC), this Tylose MHS 150009 P4 grade is ideal for use in block flooring adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades - water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose..
Tylose MHS 150009 P4 
Technical data sheet Tylose MHS 150009 P4 OOH CH, CH2, CH3

Tylose MHS 150009 P4 Brookfield RV, 20rpM, 1.0%, 20 ° C, 20 ° GH
Tylose MHS 150009 P4 Used in gypsum based plasters.
Tylose MHS 150009 P4 Thin layer plasters are used based on gypsum. Used in Tylose MHS 150009 P4 Gypsum-Lime-Plasters.
Tylose MHS 150009 P4 is used in tile adhesives.
 
 Tylose MHS 150009 P4 
Technical data sheet
Consistent development of Tylose MHS 150009 P4 : fast Water retention: very high
Tylose MHS 150009 P4 Product features
Constitution: Methylhydroxyethyl cellulose modified
The appearance of Tylose MHS 150009 P4 : powder Delayed resolution: no
Tylose MHS 150009 P4 : high etherification Thickening effect: medium
Tylose MHS 150009 P4 particle size: fine powder Viscosity level: 150000 mPas
Moisture of Tylose MHS 150009 P4 : 6%
NaCl content of Tylose MHS 150009 P4 : ≤ 1.5%
Particle size of Tylose MHS 150009 P4 : <125um: min. 85%
Particle size of Tylose MHS 150009 P4 : <100um: min. 70%
Viscosity of Tylose MHS 150009 P4 : 5600-8000 mPas

Final consistency of Tylose MHS 150009 P4 : moderate Effect on cement hydration: medium
Tylose MHS 150009 P4 sag resistance: medium Heat stability: high
Tylose MHS 150009 P4 Water demand: high
Tylose MHS 150009 P4 Packaging, Storage, Safety instructions Packaging, Storage, Safety instructions Tylose MHS 150009 P4 
Tylose MHS 150009 P4 Like all fine organic matter, Tylose MHS 150009 P4 poses a dust explosion hazard. Deposits should be kept to a minimum so that no sediment / air mixture is formed. Tylose MHS 150009 P4 Sources of ignition: bare flames, hot surfaces, sparks and static electricity should be avoided. Tylose MHS 150009 P4 begins to decompose about 200 ° C. Ignition temperature> 360 ° C. Tylose MHS 150009 P4 easily burns and a fire could occur. Tylose MHS 150009 P4 should be stored for a long time when stored in closed containers or Tylose MHS 150009 P4 in its original packaging in a dry place at room temperature. In case of high viscosity grades, a slow loss of viscosity
long-term storage (> 1 year). Tylose absorbs water from moist air. Tylose MHS 150009 P4 After opening, the container should be closed and kept tightly closed. Tylose MHS 150009 P4 is supplied in multi-layer paper bags with a polyethylene interlayer and / or big bags. Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention and heat stability, and an effect on moderate sag resistance and cement hydration. Consisting of methyl hydroxyethyl cellulose (MHEC), this Tylose MHS 150009 P4 grade is ideal for use in block flooring adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades - water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose..Tylose MHS 150009 P4 Application Performance.Tylose MHS 150009 P4 Used in building materials. Consistency improvement of Tylose MHS 150009 P4 : very fast Tylose MHS 150009 P4 Final consistency: medium.
Tylose MHS 150009 P4 
Product Properties
Constitution: Methyl hydroxyethyl cellulose modified
Appearance: powder
Etherification: high
Particle size: fine powder
Delayed solubility: no
Level of viscosity:
according to Höppler 15000 mPa•s
Tylose MHS grades - water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose
 
 Application Performance
Building Materials
Consistency development: very fast
Final consistency: moderate
Sag resistance: moderate
Water demand: high
Water retention: very high
Influence on cement hydration: moderate
Heat stability: high
Recommended Fields Of Application
Building Materials
Block laying adhesive
Gypsum mounting binder
Gypsum spray plaster
Nomenclature Information
MHS 150003 P4 Sag resistance: medium.Tylose MHS 150009 P4 Water demand: high.Tylose MHS 150009 P4 Water retention: very high.Tylose MHS 150009 P4 Effect on cement hydration: medium.Tylose MHS 150009 P4 Heat stability: high.Tylose MHS 150009 P4 Recommended Application Areas. Tylose MHS 150009 P4 is used in building materials.
Tylose MHS 150009 P4 
TYLOSE MH 150003 P4 Physical State: Free Powder
TYLOSE MH 150003 P4 Humidity: ≤ 6%
TYLOSE MH 150003 P4 NaCl content: ≤ 1.5%
TYLOSE MH 150003 P4 Grain size: <100μm: min. 90%
TYLOSE MH 150003 P4 Grain size: <63μm: min. 65%
Tylose MHS 150009 P4 Properties: Methyl hydroxyethyl cellulose modified
Tylose MHS 150009 P4 Appearance: powder
Tylose MHS 150009 P4 Etherification: High
Tylose MHS 150009 P4 Particle size: fine powder
Tylose MHS 150009 P4 Delayed resolution: no
Tylose MHS 150009 P4 Viscosity level: according to Höppler 15000 mPa s
Tylose MHS 150009 P4 is soluble in water,
Tylose MHS 150009 P4 nonionic, highly etherified methyl hydroxyethyl cellulose
Tylose MHS 150009 P4 Application Performance
Tylose MHS 150009 P4 Used in building materials.
Consistency improvement of Tylose MHS 150009 P4 : very fast
Tylose MHS 150009 P4 Final consistency: medium
Tylose MHS 150009 P4 Sag resistance: medium
Tylose MHS 150009 P4 Water demand: high
Tylose MHS 150009 P4 Water retention: very high
Tylose MHS 150009 P4 Effect on cement hydration: medium
Tylose MHS 150009 P4 Heat stability: high
Tylose MHS 150009 P4 Recommended Application Areas
Tylose MHS 150009 P4 Used in building materials.
Tylose MHS 150009 P4 is used as block flooring adhesive.
Tylose MHS 150009 P4 Used as plaster mounting binders.
Tylose MHS 150009 P4 is used in plaster spray plaster.
Nomenclature Information
Gypsum Based Hand and Machine Plasters
Product Name Chemical Description Uses
Type MH
 Tylose MHS 150009 P4 Packaging, Storage, Safety instructions Packaging, Storage, Safety instructions Tylose MHS 150009 P4 
Tylose MHS 150009 P4 begins to decompose about 200 ° C. Ignition temperature> 360 ° C. Tylose MHS 150009 P4 easily burns and a fire could occur. Tylose MHS 150009 P4 should be stored for a long time when stored in closed containers or Tylose MHS 150009 P4 in its original packaging in a dry place at room temperature. In case of high viscosity grades, a slow loss of viscosity. Long-term storage (> 1 year). Tylose absorbs water from moist air. Tylose MHS 150009 P4 After opening, the container should be closed and kept tightly closed. Tylose MHS 150009 P4 is supplied in multi-layer paper bags with a polyethylene interlayer and / or big bags. Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 should be stored for a long time when stored in closed containers or Tylose MHS 150009 P4 in its original packaging in a dry place at room temperature. In case of high viscosity grades, a slow loss of viscosity long-term storage (> 1 year). Tylose absorbs water from moist air. Tylose MHS 150009 P4 After opening, the container should be closed and kept tightly closed. Tylose MHS 150009 P4 is supplied in multi-layer paper bags with a polyethylene interlayer and / or big bags. Tylose MHS 150009 P4 is a water soluble substance. Tylose MHS 150009 P4 is non-ionic. Tylose MHS 150009 P4 is highly etherified. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 is a modified methyl hydroxyethyl cellulose powder. Tylose MHS 150009 P4 provides very fast consistency development, high water demand, water retention and heat stability, and an effect on moderate sag resistance and cement hydration. Consisting of methyl hydroxyethyl cellulose (MHEC), this Tylose MHS 150009 P4 grade is ideal for use in block flooring adhesives and gypsum mounting binders and spray plasters. Tylose MHS 150009 P4 grades - water soluble, nonionic, highly etherified methyl hydroxyethyl cellulose..Tylose MHS 150009 P4 Application Performance.Tylose MHS 150009 P4 Used in building materials. Consistency improvement of Tylose MHS 150009 P4 : very fast. 150003 P4 Final consistency: medium Tylose MHS 150009 P4 Sagging resistance: medium.Tylose MHS 150009 P4 Water demand: high.Tylose MHS 150009 P4 Water retention: very high Tylose MHS 150009 P4 Effect on cement hydration: medium.Tylose MHS 150009 P4 Heat Tylose MHS 150009 P4 Recommended Application Areas Tylose MHS 150009 P4 Used in building materials Tylose MHS 150009 P4 Like all fine organic materials, Tylose MHS 150009 P4 poses a dust explosion hazard. Deposits should be kept to a minimum so that no sediment / air mixture is formed. Tylose MHS 150009 P4 Sources of ignition: bare flames, hot surfaces, sparks and static electricity should be avoided.
 
Gypsum Based Hand and Machine Plasters
Product Name Chemical Description Uses
TYLOSE MH 10.001 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 10.000 mPas Decorative mineral based plasters, Smooth block adhesives, Tile adhesives, Exterior coating and insulation systems
TYLOSE MH 10.007 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 10.000 mPas Decorative mineral based plasters, Smooth block adhesives, Tile adhesives, Exterior coating and insulation systems
TYLOSE MH 15.000 P4 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 15.000 mPas Ready-mixed concrete joint fillers, Tile adhesives Exterior coating and insulation systems, Gypsum-based joint compounds, Insulation Plasters
TYLOSE MH 15.002 P6 Methyl Hydroxy Ethyl Cellulose Höppler falling ball viscometer 15.000 mPas Cement-lime based plaster, Gypsum-Lime based plaster, Smooth bl
Y Delayed solubility products
H Hydroxyethyl 30000 K Readily soluble granules
O Hydroxypropyl 15000 N non-delayed solubility products
A Allyl 10000 (only for Tylose H grades) *
X Hydrophobe 6000 
etherification 4000 Degree of particle size
2000 Types of granules:
Degree of 1000 G4 Granules (< 500 μm)
B etherification 300 G6 Granules (< 400 μm)
F Special higher 200 G6 Granules (< 400 μm)
S degrees of . Powder types:
T etherification, . P2 Powder (< 180 μm)
depending on the . P3 Fine Powder (< 125 μm)
individual type of 01 P4 Fine powder (< 125 μm)
ether 02 P6 Ultra fine powder (< 100 μm)

Recommended fields of application 
Gypsum based joint filler Plaster adhesives, gypsum based
Application performance
Consistency development: fast
Water retention: very high
Final consistency: very high
Influence on cement hydration: moderate
Sag resistance: high
Heat stability: high
Water demand: very high
Packaging, Storage, Safety instructions Like all fine-particle organic substances, cellulose ethers constitute a dust explosion hazard. Dust formation and deposits must be kept to a minimum so that no ignitable dust/air mixtures can form. Ignition sources such as naked flames, hot surfaces, sparks and static electricity should be avoided. Tylose starts to decompose at about 200°C. Its ignition temperature is >360°C. Tylose burns easily and the fire may spread. When stored in closed containers, or in its original packaging in a dry place at room temperature, Tylose can be kept for a long time. In the case of high viscosity grades, a slow loss of viscosity can be measured after lengthy storage (>1 year). Tylose absorbs water from moist air. Once opened, container must be resealed and kept tightly closed. This Tylose-type is supplied in multi-ply paper bags with polyethylene intermediate layer and/or in big bags.

TYLOSE MHS 150009 P4
Starch, 2-hydroxypropyl ether; tylovis se 7 cas no: 9049-76-7
TYLOSE MHS 60000 YP4
DESCRIPTION:
TYLOSE MHS 60000 YP4 is Methyl hydroxyethyl cellulose.
TYLOSE MHS 60000 YP4 Acts as a rheology modifier.
TYLOSE MHS 60000 YP4 Offers low gloss, low pigment compatibility and high thickening effect as well as moderate water retention, high wet scrub resistance, moderate anti-spattering and moderate pseudoplasticity.

TYLOSE MHS 60000 YP4 Has no bio stability.
TYLOSE MHS 60000 YP4 is Used in emulsion based tile adhesives.
TYLOSE MHS 60000 YP4 is water soluble, non-ionic, highly etherified methyl hydroxyethyl cellulose.


APPLICATIONS OF TYLOSE MHS 60000 YP4:
TYLOSE MHS 60000 YP4 is Used as Emulsion tile adhesive
TYLOSE MHS 60000 YP4 is Used as Emulsion glue
TYLOSE MHS 60000 YP4 is Used as Wet joints


SAFETY INFORMATION ABOUT TYLOSE MHS 60000 YP4:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

Packaging, storage, safety instructions:

Like all organic powder substances, cellulose ethers present a dust explosion hazard.
In order to avoid combustible dust-air mixtures, the risk of dust generation and accumulation must be minimised.
Avoid sources of ignition such as open flames, hot surfaces, sparks, and electrical disturbances.

Tylose begins to decompose at around 200˚C.
The flash point is greater than 360˚C.
Tylose burns easily and fire can spread.

Tylose can be stored for a long time if stored in a closed container or in its original packaging in a dry place at room temperature.
For high-viscosity types, a slight loss of viscosity may occur after long-term storage (more than 1 year).
Tylose absorbs water from humid air.
An opened container must be resealed tightly.


PHYSICAL AND CHEMICAL PROPERTIES OF TYLOSE MHS 60000 YP4:
Physical state : Solid
Appearance : Powder.
Colour : whitish
Odour : odourless
pH : 6 – 8 10g/l
Auto-ignition temperature : > 170 °C
Density : Density: 1.1 – 1.5 g/cm³ 20 °C
Solubility : Water: > 10 g/l @ 20°C
Log Pow : < 1
Explosive properties : Product is not explosive. Dust may form explosive mixture in air.
Minimum ignition energy : > 10 mJ
Conbustion class : 5
Smoldering temperature : >450 °C
pmax : 10 bar
Dust explosion category : ST1
KSt : < 200 bar*m/s
Ignition temperature : > 400 °C
Constitution: Methyl hydroxypropyl cellulose
Appearance: powder
Etherification: high
Particle size: fine powder
Delayed solubility: yes
Level of viscosity according to Höppler: 60000 mPa•s
Humidity : ≤6%
NaCl content: ≤1.5%
Grain size: <125µm: min. 85%
Grain size: <100µm: min. 70%
Viscosity: 27000 – 34000 mPas
Brookfield RV, 20rpM, 1.9%20°C, 20°GH


APPLICATION PERFORMANCE WITH BUILDING MATERIALS:
Consistency development: fast
Final consistency: low
Sag resistance: low
Water demand: low
Water retention: very high
Influence on cement hydration: low
Heat stability: high



TYLOSE PSO 810001
DESCRIPTION:

Tylose PSO 810001, a methyl hydroxypropyl cellulose (MHPC) which acts as a thickener for a much broader range of organic solvents.
Tylose PSO 810001 performs exceedingly well in most polar organic solvents, organic solvent mixtures and organic solvent/water systems.
Fields of application include paint strippers, adhesives and fuel pastes.

CAS NO: 9004-65-3


APPROPRIATE SOLVENTS FOR TYLOSE PSO 810001 – SOME TYPICAL EXAMPLES:
Alcohols:
Methanol Ethanol Propanol Isopropanol Octanol Butyl diglycol 1,3-Butanediol Glycerol Diethylene glycol
Aldehydes/Ketones:
Acetone (propanone) 2-Butanone
Amides:
DMF (Dimethyl formamide) NEP (N-Ethyl-2-pyrrolidone) NMP (N-Methyl-2-pyrrolidone)
Esters:
Dibasic Esters BDGA (2-(2-Butoxyethoxy)ethyl acetate)
Ethers:
DPM (Dipropylene glycol methyl ether) TPM (Tripropylene glycol methyl ether) THF (Tetrahydrofuran) 1,3-Dioxolane



Halogenated Carbohydrates:
Methylene chloride Chloroform (trichloromethane)
Others:
DMSO (Dimethyl sulfoxide) Pyridine


SAFETY INFORMATION ABOUT TYLOSE PSO 810001:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




PHYSICAL AND CHEMICAL PROPERTIES OF TYLOSE PSO 810001:
Physical state : Solid
Appearance : Powder.
Colour : whitish
Odour : odourless
pH : 6 – 8 10g/l
Auto-ignition temperature : > 170 °C
Density : Density: 1.1 – 1.5 g/cm³ 20 °C
Solubility : Water: > 10 g/l @ 20°C
Log Pow : < 0
Explosive properties : Product is not explosive. Dust may form explosive mixture in air.
Minimum ignition energy : > 10 mJ
Conbustion class : 5
Smoldering temperature : > 450 °C
pmax : 10 bar
Dust explosion category : ST1
KSt : < 200 bar*m/s
Ignition temperature : > 400 °C



TYLOVIS SE 7
C.I. Pigment Blue 29; C.I. 77007; Ultramarine; Ultramarine blue pigment; Azure blue; Azzurrum ultramarine; Azzurrum transmarinum; Azzuro oltramarino; azur d'Acre; pierre d'azur; Lazurstein; cas no: 57455-37-5, 67053-79-6
UCAR ESTER EEP
UCAR Ester EEP is a slow evaporating ether–ester solvent with excellent solvent properties for a wide range of coating applications.
UCAR Ester EEP provides excellent film formation due to its enhanced flow and leveling characteristics.
UCAR Ester EEP is a flammable, colorless liquid.

CAS: 763-69-9
MF: C7H14O3
MW: 146.18
EINECS: 212-112-9

UCAR Ester EEP is a low volatility ether ester with good solubility for a wide range of coating polymers.
The ether ester group, linear structure, and propionyl group at the molecular center allow this material to combine some properties not found in other solvents, such as slow volatilization rate, resistance to solvent cracking in baking applications, and compatibility with a wide range of polymers.

UCAR Ester EEP has high solubility, low solution viscosity (relative to its evaporation rate), good solvent release from the film, good flow and leveling properties in a wide range of coatings.
UCAR Ester EEP solvent has moderate odor, low surface tension and high resistivity; it has the special function of preventing silver powder from thickening and blackening; UCAR Ester EEP also has the effect of preventing sedimentation in the use of aluminum silver paste.

UCAR Ester EEP is a cycloaddition product of ethyl 3-ethoxypropanoate.
UCAR Ester EEP has been shown to be more chemically stable than the reactants and has an increased uptake in the reaction solution.
UCAR Ester EEP is able to undergo a cycloaddition process with diethyl succinate under conditions of high temperature and pressure, leading to the formation of methyl ethyl malonic acid.

This chemical reaction takes place via an intermolecular hydrogen bonding interaction between the ethoxy group on one molecule and the ester group on the other molecule.
The cyclohexane ring on each molecule also forms a hydrogen bonding interaction with UCAR Ester EEP's corresponding methyl or ethyl groups.
UCAR Ester EEP is not reactive in its pure form but can undergo reactions when exposed to chemicals such as potassium hydroxide, which leads to its degradation into propionic acid and ethanol.

UCAR Ester EEP Chemical Properties
Melting point: -75 °C
Boiling point: 166 °C (lit.)
Density: 0.95 g/mL at 25 °C (lit.)
Vapor density: 5.03 (vs air)
Vapor pressure: 2.0 hPa (25 °C)
Refractive index: n20/D 1.405(lit.)
Fp: 126 °F
Storage temp.: Store below +30°C.
Solubility water: soluble54.1 g/L at 20°C
Form: Liquid
Color: Clear
Water Solubility: 1.6 g/100 mL (20 ºC)
InChIKey: BHXIWUJLHYHGSJ-UHFFFAOYSA-N
LogP: 1.47 at 20℃
CAS DataBase Reference: 763-69-9(CAS DataBase Reference)
NIST Chemistry Reference: UCAR Ester EEP (763-69-9)
EPA Substance Registry System: UCAR Ester EEP (763-69-9)

Uses
UCAR Ester EEP is used in the synthesis of phenols and selective inhibitors of cyclin-dependant kinase 4/6 for novel cancer therapies.
UCAR Ester EEP is also used as a solvent to prepare polymers.
Further, UCAR Ester EEP is used in paints and coatings.
UCAR Ester EEP used as solvent in preparing new polymers.
UCAR Ester EEP is mainly used in automotive coatings (original paint, refinishing paint), plastic paint, paint for household appliances, and can be used in screen printing inks, other inks and graphic products, and slow-drying solvents for high-grade inks.

Reactivity Profile
UCAR Ester EEP is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Liquid or mist may irritate th eyes and skin.
May cause headache, nausea and vomiting, central nervous system depression with dizziness, drowsiness and unconsciousness.

Synonyms
Ethyl 3-ethoxypropionate
Ethyl 3-ethoxypropanoate
763-69-9
3-Ethoxypropionic acid ethyl ester
Propanoic acid, 3-ethoxy-, ethyl ester
Ethyl-3-ethoxypropionate
Ethoxypropionic acid, ethyl ester
Ethyl beta-ethoxypropionate
NSC 8870
PROPIONIC ACID, 3-ETHOXY-, ETHYL ESTER
EINECS 212-112-9
Ethylester kyseliny 3-ethoxypropionove
UNII-EC38RSJ79J
BRN 1751976
EC38RSJ79J
Ethyl .beta.-ethoxypropionate
AI3-03254
DTXSID0027309
Ethylester kyseliny 3-ethoxypropionove [Czech]
NSC-8870
3-Ethoxy-propionic acid ethyl ester
EC 212-112-9
EEP Solvent
Ektapro EEP
MFCD00051356
Ethyl3-ethoxypropanoate
ethyl-3-ethoxypropionat
EEP (CHRIS Code)
Ethyl 3-Ethyoxypropionate
3-ethoxypropionic acid ethyl
SCHEMBL37036
WLN: 2OV2O2
DTXCID907309
CHEMBL3561286
Ethyl 3-ethoxypropionate, 99%
BHXIWUJLHYHGSJ-UHFFFAOYSA-
NSC8870
Ethyl 3-ethoxypropionate, >=99%
3-ethoxy-propanoic acid ethyl ester
Tox21_200179
Ethyl ester of 3-ethoxypropanoic acid
AKOS000120095
CS-W013312
.beta.-Ethoxypropionic acid ethyl ester
NCGC00248553-01
NCGC00257733-01
CAS-763-69-9
LS-124674
E0319
FT-0625748
FT-0652028
EN300-20634
E83003
A838683
J-520873
Q22829038
InChI=1/C7H14O3/c1-3-9-6-5-7(8)10-4-2/h3-6H2,1-2H3
EEP
UCAR N-BUTYL PROPIONATE
UCAR n-Butyl Propionate is a butyl ester of propionic acid.
UCAR n-Butyl Propionate has the chemical formula CH3CH2COO(CH2)3CH3.
UCAR n-Butyl Propionate is a plant metabolite, a human metabolite and an insect attractant.

CAS: 590-01-2
MF: C7H14O2
MW: 130.18
EINECS: 209-669-5

UCAR n-Butyl Propionate is a propanoate ester of butan-1-ol.
UCAR n-Butyl Propionate has a role as a plant metabolite, a human metabolite, an insect attractant and a flavouring agent.
UCAR n-Butyl Propionate is functionally related to a butan-1-ol.
A water-white liquid with an apple-like odor.
Less dense than water.
Flash point 90°F.

May irritate skin and eyes.
UCAR n-Butyl Propionate used to make perfumes and flavorings.
UCAR n-Butyl Propionate is used as a solvent or lacquer thinner; and in perfumes and flavoring
UCAR n-Butyl Propionate is an ester of propionic acid, which is a naturally occurring fatty acid found in many plants and animals.

UCAR n-Butyl Propionate is a colorless liquid with a sweet, fruity odor and a low vapor pressure.
UCAR n-Butyl Propionate is used as a flavoring agent and a solvent in food, pharmaceutical, and cosmetic products.
UCAR n-Butyl Propionate is also used as a plasticizer and in the manufacture of perfumes, dyes, and other chemicals.
In addition, UCAR n-Butyl Propionate is used as a solvent in the production of paints, varnishes, and other coatings.

UCAR n-Butyl Propionate Chemical Properties
Melting point: -75 °C
Boiling point: 145 °C/756 mmHg (lit.)
Density: 0.875 g/mL at 25 °C (lit.)
Vapor density: 4.5 (vs air)
Vapor pressure: 4.6hPa at 20℃
Refractive index: n20/D 1.401(lit.)
FEMA: 2211 | BUTYL PROPIONATE
Fp: 101 °F
Storage temp.: Flammables area
Solubility: 1.5g/l
Form: Liquid
Color: Clear colorless
Odor: at 100.00 %. earthy sweet weak rose
Odor Type: fruity
Odor Threshold: 0.036ppm
Water Solubility: 0.2 g/100 mL (20 ºC)
JECFA Number: 143
Merck: 14,1587
LogP: 2.67 at 20℃
CAS DataBase Reference: 590-01-2(CAS DataBase Reference)
NIST Chemistry Reference: PUCAR n-Butyl Propionate(590-01-2)
EPA Substance Registry System: UCAR n-Butyl Propionate (590-01-2)

UCAR n-Butyl Propionate is a flammable, colorless to straw-yellow liquid with an apple-like odor.
UCAR n-Butyl Propionate has a characteristic earthy, faintly sweet odor and apricot-like taste.
Reported found in fresh apple, apple juice, melon, strawberry, Gruyere de Comte cheese and plum.
UCAR n-Butyl Propionate is a colorless liquid with a pear drops-like or apple-like odor.
The liquid is less dense than water.
UCAR n-Butyl Propionate's vapor is 4.5 times denser than the air at the mean ocean level.

Uses
UCAR n-Butyl Propionate is a moderately fast evaporating solvent.
UCAR n-Butyl Propionate's linear structure contributes to effective viscosity reduction and improves solvent diffusion from coating films.
UCAR n-Butyl Propionate is used solvent for nitrocellulose, retarder in lacquer thinner, ingredient of perfumes, flavors.

UCAR n-Butyl Propionate is used to make fragrances, perfumes and as a flavoring.
UCAR n-Butyl Propionate is also used in paints and primers for auto body or engine, appliance coatings (paints designed specifically for painting household items and vehicles like microwave ovens, refrigerators and automobiles), enamels, lacquers, and printing inks, as a solvent for adhesives and nitrocellulose, and in polymerization reactions for acrylic resins.

Preparation
By esterification of propionic acid with n-butyl alcohol in the presence of concentrated H2SO4 or p-toluene sulfonic acid.
UCAR n-Butyl Propionate is derived by esterification of propionic acid with butanol.

CH3CH2COOH + CH3(CH2)3OH ⇌ CH3CH2COO(CH2)3CH3 + H2O

Hazards and Toxicity
UCAR n-Butyl Propionate may irritate skin and eyes.
Exposure to its vapor may cause eye and respiratory system irritation.
Upon ingestion, causes abdominal pain and nausea.
UCAR n-Butyl Propionate is very flammable.
UCAR n-Butyl Propionate may ignite even at ambient temperatures.
Above 32 °C (90 °F), explosive mixtures with air may be formed.
Strong oxidizing acids may cause a violent reaction that is sufficiently exothermic to ignite UCAR n-Butyl Propionate and the reaction products.
Upon catching a fire, irritating, toxic and suffocating gases may be produced, such as carbon dioxide and carbon monoxide.

Reactivity Profile
UCAR n-Butyl Propionate is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Synonyms
Butyl propionate
Butyl propanoate
590-01-2
N-BUTYL PROPIONATE
Propanoic acid, butyl ester
n-Butyl propanoate
Propionic acid, butyl ester
Propionic Acid Butyl Ester
FEMA No. 2211
Butyl propionate (natural)
NSC 8449
n-Butyl n-propionate
EINECS 209-669-5
propanoic acid butyl ester
UN1914
UNII-2NXC4AK99E
BRN 1700932
2NXC4AK99E
Butyl ester of propanoic acid
AI3-24352
DTXSID5027223
NSC-8449
Butyl propionate [UN1914] [Flammable liquid]
4-02-00-00708 (Beilstein Handbook Reference)
n-butylpropionate
propionic acid butyl
MFCD00009448
Butyl propionate, 99%
Propionic acid-butyl ester
SCHEMBL26794
DTXCID907223
BUTYL PROPIONATE [FHFI]
CHEMBL3561586
N-BUTYL PROPIONATE [MI]
CHEBI:89831
FEMA 2211
Butyl propionate, >=98%, FG
NSC8449
Tox21_201691
Butyl propionate, analytical standard
NA1914
AKOS015907872
LS-2607
UN 1914
NCGC00249097-01
NCGC00259240-01
CAS-590-01-2
FT-0623318
FT-0623319
P0502
Butyl propanoate; (Propanoic acid, butyl ester)
Butyl propionate [UN1914] [Flammable liquid]
A832103
Q2726127
InChI=1/C7H14O2/c1-3-5-6-9-7(8)4-2/h3-6H2,1-2H
UCAR N-PENTYL PROPIONATE
A propanoate ester of pentan-1-ol.
Colorless liquid with an apple-like odor.
Floats on water.

CAS: 624-54-4
MF: C8H16O2
MW: 144.21
EINECS: 210-852-7

UCAR n-Pentyl Propionate is an organic ester formed by the condensation of pentan-1-ol and propanoic acid.
UCAR n-Pentyl Propionate is a colorless liquid with an apple-like odor, that floats on water.

UCAR n-Pentyl Propionate Chemical Properties
Melting point: -75 °C
Boiling point: 169 °C(lit.)
Density: 0.873 g/mL at 25 °C(lit.)
Vapor pressure: 1.7hPa at 20℃
FEMA: 2082 | ISOAMYL PROPIONATE
Refractive index: n20/D 1.4074(lit.)
Fp: 133 °F
Storage temp.: Flammables area
Color: Colorless liquid
Odor: fruity, apricot-pineapple odor
Odor Type: fruity
Water Solubility: 706.7mg/L(20 ºC)
LogP: 2.83 at 25℃
EPA Substance Registry System: UCAR n-Pentyl Propionate (624-54-4)

Uses
UCAR n-Pentyl Propionate, an ester, has been employed for the evaluation of experimental values of HEm and VEm at 318.15K for the binary mixtures of alkyl propanoates with alkanes.

Reactivity Profile
UCAR n-Pentyl Propionate is an ester.
Esters react with acids to liberate heat along with alcohols and acids.
Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products.
Heat is also generated by the interaction of esters with caustic solutions.
Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Special Hazards of Combustion Products: Irritating vapors and toxic gases, such as carbon dioxide and carbon monoxide, may be formed when involved in fire.
Exposure can cause irritation of eyes, nose and throat.

Synonyms
Pentyl propionate
Pentyl propanoate
AMYL PROPIONATE
n-Pentyl propionate
624-54-4
Amyl propanoate
Propanoic acid, pentyl ester
Pentyl propanate
n-Amyl propionate
n-Pentyl propanoate
Propionic acid, pentyl ester
NSC 7931
n-Amyl propionate (natural)
N-Amyl n-propionate
EINECS 210-852-7
propionic acid pentyl ester
BRN 1747102
AI3-24356
UNII-826P0596UJ
NSC-7931
826P0596UJ
EC 210-852-7
Propionic acid, pentyl ester (6CI,7CI,8CI)
PPE (CHRIS Code)
Pentyl propionate, >=99%
SCHEMBL20847
DTXSID4041606
CHEBI:87373
NSC7931
TWSRVQVEYJNFKQ-UHFFFAOYSA-N
MFCD00048849
AKOS015902810
LS-121581
FT-0622381
Q3050158
UCAR N-PROPYL PROPIONATE
Acts as a fast evaporating, non-HAP solvent.
Offers stronger solvency for high solids coatings.
Provides proper volatility for high solids coatings and printing inks applications.

CAS: 106-36-5
MF: C6H12O2
MW: 116.16
EINECS: 203-389-7

Improves solvent diffusion from coating films.
Possesses linear structure giving faster diffusion through coating and ink films.
Imparts high electrical resistance for electrostatically sprayed coatings.
Used in automotive refinish, OEM coatings, appliance coatings, and printing inks.
Reported found among the volatile constituents of grape var. white sauvignon.
Also reported found in fresh apple, apple juice, apricot, melon, papaya, pear, Gruyere de Comte cheese, rum, cider, popcorn, durian, olive, malt whiskey and coffee.
UCAR n-Propyl Propionate is a propanoate ester resulting from the formal condensation of the hydroxy group of propanol with the carboxy group of propanoic acid.

UCAR n-Propyl Propionate has a role as a human metabolite, a rat metabolite, a biomarker and a fungal metabolite.
UCAR n-Propyl Propionate is functionally related to a propan-1-ol.
UCAR n-Propyl Propionate and water mixtures can be separated by pervaporation using PEBA membranes.
The diffusivity of pure UCAR n-Propyl Propionate in the PEBA membrane is about 28 times higher than pure water diffusivity.
UCAR n-Propyl Propionate is the organic compound with the molecular formula C6H12O2.

UCAR n-Propyl Propionate is the ester of propanol and propionic acid.
Like most esters, UCAR n-Propyl Propionate is a colorless liquid with a fruity odor.
The scent of UCAR n-Propyl Propionate is described as a chemically tinged pineapple or pear.
UCAR n-Propyl Propionate is used in perfumery and as a solvent.
The refractive index at 20 °C is 1.393.
Because UCAR n-Propyl Propionate is a low-odor, moderately volatile, non-HAP ester solvent with good solvent activity and versatility, UCAR n-Propyl Propionate is considered a safer substitute for toluene.

UCAR n-Propyl Propionate Chemical Properties
Melting point: −76 °C(lit.)
Boiling point: 122-124 °C(lit.)
Density: 0.881 g/mL at 25 °C(lit.)
Vapor density: 4 (vs air)
Vapor pressure: 18.53hPa at 25℃
Refractive index: n20/D 1.393(lit.)
FEMA: 2958 | PROPYL PROPIONATE
Fp: 76 °F
Storage temp.: Flammables area
Solubility: 5g/l
Form: Liquid
Color: Clear colorless
Specific Gravity: 0.882 (20/4℃)
Odor: at 100.00 %. sharp chemical pungent sweet fruity pineapple winey
Odor Type: chemical
Odor Threshold: 0.058ppm
Explosive limit: 1.3%(V)
Water Solubility: Soluble in water. (5g/L).
JECFA Number: 142
Merck: 14,7867
BRN: 1699993
LogP: 1.85 at 25℃
CAS DataBase Reference: 106-36-5(CAS DataBase Reference)
NIST Chemistry Reference: UCAR n-Propyl Propionate (106-36-5)
EPA Substance Registry System: UCAR n-Propyl Propionate (106-36-5)

UCAR n-Propyl Propionate has a complex, fruity odor reminiscent of apple, banana and pineapple.
UCAR n-Propyl Propionate has a somewhat pleasant, bitter flavor.

Uses
UCAR n-Propyl Propionate is a general reagent which can be used in various transesterification reactions.
UCAR n-Propyl Propionate is used as Solvent for nitrocellulose, paints, varnishes, lacquers, coating agents.
UCAR n-Propyl Propionate is a fast evaporating solvent.
UCAR n-Propyl Propionate's linear structure contributes to effective viscosity reduction and improves solvent diffusion from coating films.
UCAR n-Propyl Propionate has application in automotive refinish, OEM coatings, appliance coatings, printing inks and as polymerization solvent.
UCAR n-Propyl Propionate's good activity yields efficient resin viscosity reduction that enables the development of lower VOC coatings.
UCAR n-Propyl Propionate's high electrical resistivity is beneficial in optimizing transfer efficiency in coatings applied via electrostatic spray equipment.

Preparation
UCAR n-Propyl Propionate was synthesized by esterification of propyl alcohol with the corresponding acid in the presence of concentrated H2SO4, or in the presence of BF3.

Synonyms
PROPYL PROPIONATE
Propyl propanoate
106-36-5
Propanoic acid, propyl ester
n-Propyl propionate
n-Propyl propanoate
Propionic acid, propyl ester
n-Propyl n-propionate
Propylester kyseliny propionove
FEMA No. 2958
Propionic Acid Propyl Ester
Propyl propionate (natural)
NSC 72022
Propionic acid n-propyl ester
n-Propylpropropionate
Propyl ester of propanoic acid
EINECS 203-389-7
UNII-G09TRV00GK
Propanoic acid propyl ester
Propionic acid-propyl ester
Propylester kyseliny propionove [Czech]
BRN 1699993
G09TRV00GK
AI3-24357
DTXSID4042337
CHEBI:89828
NSC-72022
WE(3:0/3:0)
4-02-00-00707 (Beilstein Handbook Reference)
Propyl-propanoate
chlorhexidineacetate
propionic acid propyl
Propionate de propyle
n-Propyl n-propanoate
Propyl propionate, 99%
Propionoic acid propyl ester
SCHEMBL62961
WLN: 3OV2
PROPYL PROPANOATE [MI]
PROPYL PROPIONATE [FCC]
CHEMBL3185284
DTXCID2022337
PROPYL PROPIONATE [FHFI]
FEMA 2958
AMY21939
NSC72022
Tox21_301107
LMFA07010412
MFCD00009373
AKOS008947790
LS-3080
Propyl propionate, >=98%, FCC, FG
NCGC00248289-01
NCGC00255007-01
CAS-106-36-5
LS-13177
FT-0631593
P0511
F87292
J-001582
Q3119221
Propyl propionate, natural (US), >=98%, FCC, FG
ULTIMOPURE ISOSTEARIC ACID
UltimoPure Isostearic Acid is a unique fatty acid.
UltimoPure Isostearic Acid is useful in pharmaceutical, personal care, and cosmetic products.


CAS Number: 30399-84-9 / 2724-58-5
EC Number: 250-178-0
MDL number: MFCD00044082
Chem/IUPAC Name: Isooctadecanoic acid
INCI NAME: Isostearic Acid
Empirical Formula (Hill Notation): C18H36O2



SYNONYMS:
ISOOCTADECANOIC ACID, isostearic, 16-METHYLHEPTADECANOIC ACID, Isostearinsure, ISOSTEARIC ACID, 16-methyl-heptadecanoicaci, ISOSTEARIC ACID MIXED ISOMERS, Heptadedecanoicacid,16-Methyl, Heptadecanoic acid, 16-methyl-, Iso Octadecanoic Acid, Isooctadecanoic acid, Iso-octadecanoic acid, 16-methyl Heptadecanoic acid, ISOOCTADECANOIC ACID,Heptadecanoic acid, 16-methyl-, 16-Methylmargaric acid, Ar Prisorine 3505, Emersol 873, Isooctadecanoic acid, Prisorine 3509



Isostearic acid is a fatty acid molecule with an 18-carbon atom chain backbone.
UltimoPure Isostearic Acid is an isomer of stearic acid, meaning that they both have a chemical formula of C18H36O2, but differ in the arrangement of their atoms.


While stearic acid has a linear carbon chain with 18 carbon atoms, UltimoPure Isostearic Acid as a carbon chain with 17 atoms and a single carbon branch at the 16th carbon atom.
UltimoPure Isostearic Acid's chemical structure can be represented as (CH3)2CH(CH2)14CO2H.


UltimoPure Isostearic Acid is found naturally in meat products and vegetable oils.
UltimoPure Isostearic Acid is a methyl-branched fatty acid that is heptadecanoic acid (margaric acid) substituted by a methyl group at position 16.


UltimoPure Isostearic Acid, also known as iso-octadecanoic acid, is an branched saturated fatty acid derived from vegetable oils.
With the chemical formula of CH3(CH2)14COOH and CAS number30399-84-9 / 2724-58-5, UltimoPure Isostearic Acid appears as a waxy white solid at room temperature.


Compared to straight-chain stearic acid, UltimoPure Isostearic Acid contains a methyl branch on its carbon chain that gives it exceptional properties.
The methyl branch results in a lower melting point (around 52-55°C) and imparts greater solubility in oil phases.


UltimoPure Isostearic Acid also exhibits superior viscosity characteristics.
UltimoPure Isostearic Acid is a unique fatty acid.
UltimoPure Isostearic Acid is useful in pharmaceutical, personal care, and cosmetic products.


UltimoPure Isostearic Acid is an ester that acts as a dry emollient (smooth & dry) as well as being a co-emulsifier.
UltimoPure Isostearic Acid is a fatty acid that is used as an emollient in pharmaceutical preparations.
UltimoPure Isostearic Acid is a unique fatty acid.


UltimoPure Isostearic Acid is useful in pharmaceutical, personal care, and cosmetic products.
UltimoPure Isostearic Acid, derived from natural fats, is a crucial ingredient in cosmetics, lubricants, and industrial formulations.
UltimoPure Isostearic Acid's stable properties and emulsifying capabilities enhance the performance of diverse products.


Trusted for its versatility, UltimoPure Isostearic Acid ensures quality and functionality across various applications.
UltimoPure Isostearic Acid is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral
catalyst - there is no chemical addition in this reaction, isostearic acid is based 100% on the parent oil or fat.


UltimoPure Isostearic Acid is a liquid fatty acid derived from vegetables that offers a light sensation of lubricated skin, avoiding the dry sensation of topical products.
UltimoPure Isostearic Acid generates low viscosity for good spread and acts as a cleaning agent, emollient and greasing agent.


UltimoPure Isostearic Acid is used in applications which require a liquid fatty acid with exceptional stability: thermal stability in the
case of a lubricant, odour stability for a cosmetic formulation, and oxidation stability for products with long shelf-life requirements.
The branching structure of UltimoPure Isostearic Acid also enhances its dispersing power.


UltimoPure Isostearic Acid is an exceptionally mild liquid fatty acid that offers a light lubricious feel and can be used in many skin care and colour cosmetic applications.
UltimoPure Isostearic Acid is a clear, oily liquid that is used in a wide variety of cosmetics and personal care products.


UltimoPure Isostearic Acid is a vegetable-derived liquid fatty acid that offers a light lubricious skin feel, preventing a dry afterfeel from topical products.
UltimoPure Isostearic Acid promotes low viscosity for good spreading and acts as a cleansing agent, emollient and superfatting agent and is compatible with cold processing.


UltimoPure Isostearic Acid is a mixture of branched chain 18 carbon aliphatic acids.
100% vegetable based UltimoPure Isostearic Acid.
Due to its branched structure UltimoPure Isostearic Acid has a soft skin feel; forms a highly substantive lipid film and leaves a glossy appearance.


UltimoPure Isostearic Acid is unique, highly branched, saturated fatty acid.
Additionally, UltimoPure Isostearic Acid has excellent heat stability, oxidation resistance, pigment dispensing ability, defoaming property and is compatible with various organic solvents.


UltimoPure Isostearic Acid is a liquid fatty acid created from oleic acid.
UltimoPure Isostearic Acid's claimed to have great odour, thermal and oxidation stability and is great for the stabilization of pigments and mineral particles in oils and solvents. It's quite popular in foundations.


UltimoPure Isostearic Acid is a saturated fatty acid found in a variety of animal and plant species.
UltimoPure Isostearic Acid is light light-colored, liquid fatty acid consisting of methyl branched C18 fatty acid isomers with smaller amounts of linear staurated fatty acids and oleic acid.


The low unsaturation and especially the absence of poly-unsaturation results in excellent oxidation resistance and color stability.
UltimoPure Isostearic Acid is a long chain hydrocarbon with excellent color and thermo-oxidative stability for automotive and industrial coatings


UltimoPure Isostearic Acid is recommended for polyol esters in synthetic lubricants, for textile lubricants and hydraulic fluids among other general applications
UltimoPure Isostearic Acid is a top grade for cosmetics esters applications


UltimoPure Isostearic Acid is a vegetable derived recommended for less critical applications, but with oxidation stability better than oleic acid and its derivatives
UltimoPure Isostearic Acid has some features that are transparent and odorless, unlike straight chain fatty acids.



USES and APPLICATIONS of ULTIMOPURE ISOSTEARIC ACID:
UltimoPure Isostearic Acid is used for research use only.
UltimoPure Isostearic Acid is used similar to stearic or oleic acids.
UltimoPure Isostearic Acid is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.


UltimoPure Isostearic Acid helps the formula have higher stability.
UltimoPure Isostearic Acid is commonly used in place of some stearic acid in formulas.
UltimoPure Isostearic Acid is used to make the skin feel better.


UltimoPure Isostearic Acid has been shown to have skin-moisturizing and anti-inflammatory properties, which are due to its ability to inhibit the activity of phospholipase A2.
UltimoPure Isostearic Acid also has a high degree of chemical stability and adsorption capacity.


Its adsorption mechanism is not yet well understood, but UltimoPure Isostearic Acid appears to be related to its hydroxyl group.
UltimoPure Isostearic Acid has been used successfully in the treatment of congestive heart failure and can prevent the accumulation of lipids on the surface of blood vessels, thereby reducing atherosclerosis.


UltimoPure Isostearic Acid also functions as a substrate for the synthesis of isovaleric acid, which can be used as a fragrance ingredient in cosmetic products.
UltimoPure Isostearic Acid is a high quality 16-Methylheptadecanoic acid used in synthesis.


UltimoPure Isostearic Acid has been used as molecular tool for various biochemical applications.
UltimoPure Isostearic Acid has also been used in a wide array of other chemical and immunological applications.
UltimoPure Isostearic Acid has a wide range of industrial uses.


UltimoPure Isostearic Acid functions as a surfactant – cleansing agent, and a binder.
UltimoPure Isostearic Acid is used resin modification, Metallic pastes, Inks, Waxes and wax emulsifiers, Quaternary derivatives for textile softeners and antistats, Liquid stabilizers (metal soaps), and Anti-corrosion additives.


Cosmetic Uses of UltimoPure Isostearic Acid: binding agents, cleansing agents, surfactants, and surfactant - emulsifying
UltimoPure Isostearic Acid is a component of many cell membranes and is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.


Additionally, UltimoPure Isostearic Acid can modulate the activity of certain enzymes, including lipoxygenase, cyclooxygenase, and cytochrome P450, as well as inhibit the activity of certain transcription factors, such as NF-κB and AP-1.
Moreover, UltimoPure Isostearic Acid inhibits the growth of cancer cells.


UltimoPure Isostearic Acid has also been found to have anti-inflammatory and antioxidant properties.
UltimoPure Isostearic Acid is used bath, shower & soaps, Antiperspirants & deodorants, After sun, Body care, Eye colour, Face / neck skin care, Face colour, Hair colour, Lip colour, Shaving / hair removal, and Sun protection.


UltimoPure Isostearic Acid also offers film forming properties, making it ideal for use in soaps, shaving foams and liquid cleansers.
UltimoPure Isostearic Acid is compatible with cold processing.
Recommended topical use levels of UltimoPure Isostearic Acid is 0.5-5%


UltimoPure Isostearic Acid is used in cosmetic and industrial applications for the stabilisation of pigments and mineral particles in oils and solvents.
UltimoPure Isostearic Acid is mainly used as an additive in adhesives or lubricants for both paints and personal care products.


UltimoPure Isostearic Acid is used treatment / Conditioner, Leave-in treatment / Styling, Cleansing, Lotion / Toner, Milk / Cream / Serum, Foundation / Make-up Base, and Suncare, Lipstick / Gloss.
UltimoPure Isostearic Acid is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst – there is no chemical addition in this reaction, isostearic acid is based 100% on the parent oil or fat.


UltimoPure Isostearic Acid is used in applications which require a liquid fatty acid with exceptional stability: thermal stability in the case of a lubricant, odour stability for a cosmetic formulation, and oxidation stability for products with long shelf-life requirements.
UltimoPure Isostearic Acid is used for a cosmetic formulation.


UltimoPure Isostearic Acid is used industrial applications for the stabilisation of pigments mineral particles in oils and solvents.
The branching structure of UltimoPure Isostearic Acid also enhances its dispersing power, and it is used in cosmetic and industrial applications for the stabilisation of pigments and mineral particles in oils and solvents.



WHAT DOES ULTIMOPURE ISOSTEARIC ACID DO IN A FORMULATION?
*Binding
*Cleansing
*Emulsifying
*Surfactant



FEATURES OF ULTIMOPURE ISOSTEARIC ACID:
*Vegetable-based methyl-branched saturated fatty acid.
*Good solubility with ceramides.
*Low odor with our unique purification technology.



BENEFITS OF ULTIMOPURE ISOSTEARIC ACID:
*Flexibility - allows product to deform under stress and prevents cracking.
UltimoPure Isostearic Acid can also be used in conjunction with flexible substrates
*Easy to handle offering manufacturing flexibility
*Low color for low color applications and improved aesthetics
*Thermo-oxidative stability for longer product lifetime, and allowing for exposure to high temperature conditions
*Pigment wetting - allows high loading of pigment/fillers which can bring cost savings



SCIENTIFIC FACTS OF ULTIMOPURE ISOSTEARIC ACID:
UltimoPure Isostearic Acid, a fatty acid, is a blend of different forms of octadecanoic acid, which is obtained from animal and vegetable fats and oils.
UltimoPure Isostearic Acid can be prepared from many sources including soybean oil or tallow



FUNCTIONS OF ULTIMOPURE ISOSTEARIC ACID:
*Spreading agents



PHYSICAL and CHEMICAL PROPERTIES of ULTIMOPURE ISOSTEARIC ACID:
Molecular Weight: 284.48 g/mol
Molecular Formula: C18H36O2
Canonical SMILES: CC(C)CCCCCCCCCCCCCCC(=O)O
InChI: InChI=1S/C18H36O2/c1-17(2)15-13-11-9-7-5-3-4-6-8-10-12-14-16-18(19)20/h17H,3-16H2,1-2H3,(H,19,20)
InChIKey: XDOFQFKRPWOURC-UHFFFAOYSA-N
Boiling Point: 400.8±13.0°C at 760 Torr (estimate)
Melting Point: 67.8-68.5°C
Flash Point: 225.6°C
Purity: ≥95%
Density: 0.887±0.06 g/cm3
Appearance: White powder; White to pale yellow solid
Storage: Store at 2-8°C
Assay: 0.99
EINECS: 220-336-3

MDL: MFCD00044082
Refractive Index: 1.444
Stability: Stable
Solubility: Soluble in organic solvents, insoluble in water; Soluble in acids
Chemical Properties:
pH of aqueous solution: 6.5 (slightly acidic)
Toxicity: Non-toxic
Flammability: Flammable
Hygroscopicity: Low hygroscopicity
LogP: 7.674 (estimated)
IUPAC Name: 16-methylheptadecanoic acid
Appearance: White solid (estimated)
Assay: 95.00 to 100.00%
Boiling Point: 400.00 to 401.00 °C @ 760.00 mm Hg (estimated)

Flash Point: 438.00 °F TCC (225.70 °C) (estimated)
logP (o/w): 7.674 (estimated)
Soluble in water: 0.007116 mg/L @ 25 °C (estimated)
Physical State: Solid
Color: Not available
Odor: Not available
Melting Point/Freezing Point: Not available
Initial Boiling Point and Boiling Range: Not available
Flammability (Solid, Gas): Not available
Upper/Lower Flammability or
Explosive Limits: Not available
Flash Point: Not available
Autoignition Temperature: Not available

Decomposition Temperature: Not available
pH: Not available
Viscosity: Not available
Water Solubility: Not available
Partition Coefficient (n-octanol/water): Not available
Vapor Pressure: Not available
Density: Not available
Relative Density: Not available
Relative Vapor Density: Not available
Particle Characteristics: Not available
Explosive Properties: Not available
Oxidizing Properties: Not available
Other Safety Information: Not available



FIRST AID MEASURES of ULTIMOPURE ISOSTEARIC ACID:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed
No data available



ACCIDENTAL RELEASE MEASURES of ULTIMOPURE ISOSTEARIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ULTIMOPURE ISOSTEARIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ULTIMOPURE ISOSTEARIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Choose body protection in relation to its type.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ULTIMOPURE ISOSTEARIC ACID:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Normal measures for preventive fire protection.
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage stability:
Recommended storage temperature: 2 - 8 °C
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of ULTIMOPURE ISOSTEARIC ACID:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


ULTRAMARINE BLUE PIGMENT
Ultramarine Blue Pigment is a commonly used blue pigment, widely employed in the production of paints and inks across various industries.
Known for Ultramarine Blue Pigment high color durability and stability, this pigment is a popular choice in the plastic, paint, and printing sectors.
Offering a broad color range, Ultramarine Blue Pigment contributes to both aesthetic and functional qualities in diverse applications.

CAS: 57455-37-5
MF: Al6Na8O24S3Si6
MW: 994.500988

Synonyms
Ultramarine Blue, Azure blue, 57455-37-5, UNII-I39WR998BI, I39WR998BI, C. I. 77007, Lazurite, Ultramarine, LAZURITE [MI], ULTRAMARINE [MI], 3516 ULTRA BLUE, 3522 ULTRA BLUE, ULTRAMARINE (MINERAL), CI 77007 [INCI], ULTRAMARINE BLUE (MINERAL), ULTRAMARINE BLUE CI 77007, AKOS032950034, ALUMINUM SODIUM THIOSILICATE BLUE, LAZURITE (NA5(AL3(SIO4)3S)), LAZURITE (CA2NA6(AL6(SIO4)6(SO4)S)), Q219660.

One of the distinguishing features of Ultramarine Blue Pigment is its exceptional colorfastness, ensuring that the vivid blue tones remain vibrant over time, even in challenging environmental conditions.
This quality makes Ultramarine Blue Pigment a preferred choice in sectors such as automotive coatings, where longevity and resistance to fading are paramount.

In the realm of plastic manufacturing, Ultramarine Blue Pigment plays a crucial role in providing diverse products with an attractive and consistent blue coloration.
From packaging materials to a myriad of plastic goods, Ultramarine Blue Pigment adds an aesthetic appeal while maintaining durability.
Moreover, Ultramarine Blue Pigment is a staple in the world of textile dyeing, offering textile manufacturers the means to achieve a range of blue shades with reliability and reproducibility.
Ultramarine Blue Pigment compatibility with various substrates and dyeing processes enhances its versatility in the textile industry.

Beyond its application in coloration, Ultramarine Blue Pigment is known for its chemical stability, ensuring compatibility with different formulations in the ink industry.
This stability translates into consistent performance in printing processes, making Ultramarine Blue Pigment a valuable component in the production of inks for diverse printing applications.
In summary, Ultramarine Blue Pigment stands out as a go-to blue pigment, appreciated for its enduring color qualities and versatility across industries.
Ultramarine Blue Pigment widespread use in paints, inks, plastics, textiles, and more underscores its significance in contributing to the visual appeal and functionality of a diverse array of products.

Ultramarine Blue Pigment Chemical Properties
Specific Gravity: 2.3
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 57455-37-5(CAS DataBase Reference)
EPA Substance Registry System: C.I. Ultramarine Blue Pigment (57455-37-5)

Uses
During the Middle Ages, Ultramarine Blue Pigment was used by artists as the blue from over the sea.
Ultramarine Blue Pigment was derived from the semiprecious stone, lapis lazuli, imported from Afghanistan.
Since 1828 when it was first synthesized, the supply of the pigment has become abundant.
Ultramarine pigments are used in plastics, paints, printing inks, paper, artist colors, laundry detergents (optical brightener), and toys.

Synthetic production
In 1990, an estimated 20,000 tons of ultramarine were produced industrially. The raw materials used in the manufacture of synthetic ultramarine are the following:

White kaolin,
Anhydrous sodium sulfate (Na2SO4),
Anhydrous sodium carbonate (Na2CO3),
Powdered sulfur,
Powdered charcoal or relatively ash-free coal, or colophony in lumps.[19]

The preparation is typically made in steps:
The first part of the process takes place at 700 to 750 °C in a closed furnace, so that sulfur, carbon and organic substances give reducing conditions.
This yields a yellow-green product sometimes used as a pigment.
In the second step, air or sulfur dioxide at 350 to 450 °C is used to oxidize sulfide in the intermediate product to S2 and Sn chromophore molecules, resulting in the blue (or purple, pink or red) pigment.
The mixture is heated in a kiln, sometimes in brick-sized amounts.

The resultant solids are then ground and washed, as is the case in any other insoluble pigment's manufacturing process; the chemical reaction produces large amounts of sulfur dioxide.
Ultramarine Blue Pigment poor in silica is obtained by fusing a mixture of soft clay, sodium sulfate, charcoal, sodium carbonate, and sulfur.
The product is at first white, but soon turns green "green ultramarine" when it is mixed with sulfur and heated.
The sulfur burns, and a fine blue pigment is obtained.
Ultramarine rich in silica is generally obtained by heating a mixture of pure clay, very fine white sand, sulfur, and charcoal in a muffle furnace.
A blue product is obtained at once, but a red tinge often results.
The different ultramarines—green, blue, red, and violet—are finely ground and washed with water.

Synthetic ultramarine is a more vivid blue than natural ultramarine, since the particles in synthetic ultramarine are smaller and more uniform than the particles in natural ultramarine and therefore diffuse light more evenly.
Ultramarine Blue Pigment color is unaffected by light nor by contact with oil or lime as used in painting.
Hydrochloric acid immediately bleaches it with liberation of hydrogen sulfide.
Even a small addition of zinc oxide to the reddish varieties especially causes a considerable diminution in the intensity of the color.
Modern, synthetic ultramarine blue is a non-toxic, soft pigment that does not need much mulling to disperse into a paint formulation.
ULTRAMARINE BLUE PIGMENT
UNDECANE N° CAS : 1120-21-4 "Satisfaisant" dans toutes les catégories. Origine(s) : Minérale Nom INCI : UNDECANE N° EINECS/ELINCS : 214-300-6 Classification : COV Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent d'entretien de la peau : Maintient la peau en bon état
ULTRAMOLL® VII

Ultramoll® VII is a high-performance plasticizer used in various polymer applications for its excellent flexibility and compatibility.
Ultramoll® VII is characterized by its ability to enhance the flexibility and durability of polymer products.
The chemical formula for Ultramoll® VII is proprietary, and it is commonly used in various industrial applications due to its superior properties.

CAS Number: 68515-49-1
EC Number: 271-091-4

Synonyms: Plasticizer, Ultramoll® VII, Polymer plasticizer, Ultramoll Polymer Plasticizer VII, Plasticizing Agent VII, Polymer Additive VII, Plasticizer Additive VII, PU Plasticizer VII, Ultramoll Plasticizer VII, Flexible Additive VII



APPLICATIONS


Ultramoll® VII is widely used in the formulation of flexible PVC products, providing excellent flexibility and durability.
Ultramoll® VII is essential in the manufacture of high-performance polyurethane foams, enhancing their flexibility.
Ultramoll® VII is utilized in the production of elastomers, improving their flexibility and longevity.

Ultramoll® VII is a preferred plasticizer for flexible and rigid foams due to its efficiency in enhancing flexibility.
Ultramoll® VII is used in automotive applications for its excellent flexibility and durability under various conditions.
Ultramoll® VII is found in the production of sealants and caulks, contributing to their flexibility and performance.

Ultramoll® VII is used in water-based polymer systems for its compatibility and efficiency in enhancing flexibility.
Ultramoll® VII is a key component in solvent-based polymer formulations, providing improved flexibility.
Ultramoll® VII is used in the textile industry to improve the flexibility and performance of coatings on fabrics.

Ultramoll® VII is employed in the production of rubber materials for its plasticizing properties.
Ultramoll® VII is used in the manufacturing of synthetic fibers, enhancing their flexibility and resilience.
Ultramoll® VII is used in the construction industry for high-performance coatings and sealants.

Ultramoll® VII is used in the creation of high-performance adhesives, providing improved flexibility and durability.
Ultramoll® VII is a key component in the production of plastics, enhancing their flexibility and mechanical properties.
Ultramoll® VII is utilized in the formulation of industrial coatings, ensuring improved flexibility and performance.

Ultramoll® VII is applied in the creation of specialty coatings for various industrial applications, ensuring enhanced flexibility and performance.
Ultramoll® VII is used in the production of coatings for metal surfaces, providing improved flexibility and durability.
Ultramoll® VII is essential in the creation of high-quality printing inks, enhancing flexibility and performance during printing.

Ultramoll® VII is used in the production of rubber products, ensuring consistent flexibility and performance.
Ultramoll® VII is employed in the automotive industry, used in high-performance coatings and adhesives for improved flexibility.
Ultramoll® VII is utilized in the production of wood coatings, enhancing their flexibility and durability.

Ultramoll® VII is found in the manufacture of specialty coatings for industrial machinery, providing improved flexibility and performance.
Ultramoll® VII is utilized in the formulation of adhesives and sealants, ensuring enhanced flexibility and performance.
Ultramoll® VII is a key ingredient in the production of polyurethane elastomers, enhancing their flexibility and longevity.

Ultramoll® VII is employed in the textile industry to improve the performance and flexibility of coatings on fabrics.
Ultramoll® VII is used in the rubber industry for its plasticizing properties, improving flexibility and performance.
Ultramoll® VII is essential in the production of high-performance industrial coatings, providing improved flexibility and durability.

Ultramoll® VII is a vital component in water-based and solvent-based polymer systems, ensuring enhanced flexibility and performance.
Ultramoll® VII is applied in the creation of high-performance industrial products, providing improved flexibility and durability.
Ultramoll® VII is used in the formulation of household and industrial coatings, enhancing their flexibility and performance.

Ultramoll® VII is utilized in the production of specialty coatings for electronic devices, providing improved flexibility.
Ultramoll® VII is found in the creation of specialty inks for various applications, enhancing flexibility and performance.
Ultramoll® VII is used in the production of ceramic and glass coatings, improving their flexibility and application properties.

Ultramoll® VII is applied in the creation of coatings for plastic surfaces, ensuring improved flexibility and performance.
Ultramoll® VII is utilized in the formulation of coatings for wood surfaces, providing enhanced flexibility and durability.
Ultramoll® VII is essential in the production of high-performance adhesives, ensuring improved flexibility and application properties.

Ultramoll® VII is used in the formulation of coatings for automotive applications, providing improved flexibility and performance.
Ultramoll® VII is utilized in the production of specialty adhesives and sealants, ensuring enhanced flexibility and durability.
Ultramoll® VII is found in the manufacture of coatings for industrial machinery, providing improved flexibility and performance.

Ultramoll® VII is employed in the creation of specialty coatings for various substrates, ensuring improved flexibility and performance.
Ultramoll® VII is used in the formulation of high-performance coatings for various applications, providing enhanced flexibility and performance.
Ultramoll® VII is a key component in the production of specialty inks for flexographic and gravure printing, ensuring improved flexibility and performance.

Ultramoll® VII is used in the creation of specialty inks for digital printing, providing enhanced flexibility and application properties.
Ultramoll® VII is essential in the production of high-performance industrial products, ensuring improved flexibility and performance.
Ultramoll® VII is utilized in the manufacture of environmentally friendly industrial products, providing enhanced flexibility and durability.

Ultramoll® VII is used in the creation of water-based and solvent-based products, ensuring improved flexibility and performance.
Ultramoll® VII is a critical ingredient in the formulation of specialty coatings for metal and plastic surfaces, providing enhanced flexibility and application properties.



DESCRIPTION


Ultramoll® VII is a high-performance plasticizer used in various polymer applications for its excellent flexibility and compatibility.
Ultramoll® VII is characterized by its ability to enhance the flexibility and durability of polymer products.

Ultramoll® VII is a versatile chemical compound used in various polymer applications.
Ultramoll® VII is known for its strong plasticizing properties, which improve the flexibility and performance of polymer products.
Ultramoll® VII provides excellent compatibility with a wide range of polymers, making it ideal for industrial coatings and adhesives.

Ultramoll® VII is compatible with a wide range of polymer systems, enhancing its versatility in different formulations.
Ultramoll® VII is widely used in the coatings, adhesives, elastomers, and sealants industries, among others.
Ultramoll® VII's non-toxic nature makes it safe for use in various industrial and consumer products.

Ultramoll® VII offers excellent flexibility, making it suitable for applications requiring enhanced flexibility and durability.
Ultramoll® VII is known for its ease of dispersion, ensuring uniform plasticizing in various systems.
Ultramoll® VII is essential in the creation of durable and high-performance polymer products.

Ultramoll® VII's strong plasticizing properties make it a preferred choice in the creation of high-quality industrial coatings.
Ultramoll® VII is an important precursor in the production of high-performance adhesives and sealants, providing improved flexibility.
Ultramoll® VII is widely used in the manufacture of durable and resilient polymer products, ensuring enhanced flexibility and performance.



PROPERTIES


Chemical Formula: Proprietary
Common Name: Ultramoll® VII
Molecular Structure: Proprietary
Appearance: Clear liquid
Density: 1.05 g/cm³
Viscosity: Low
Solubility: Miscible with most organic solvents
Reactivity: Low
Chemical Stability: Excellent
Compatibility: Wide range of polymer systems
Flexibility: Excellent
Dispersion: Easy



FIRST AID


Inhalation:
If Ultramoll® VII is inhaled, move the affected person to fresh air immediately.
If breathing difficulties persist, seek immediate medical attention.
If the person is not breathing, administer artificial respiration.
Keep the affected person warm and at rest.

Skin Contact:
Remove contaminated clothing and footwear.
Wash the affected skin area thoroughly with soap and water.
If skin irritation or rash develops, seek medical attention.
Launder contaminated clothing before reuse.

Eye Contact:
Flush the eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids.
Seek immediate medical attention if irritation or redness persists.
Remove contact lenses if present and easy to do; continue rinsing.

Ingestion:
Do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water.
Seek immediate medical attention.
If the person is conscious, give small sips of water to drink.

Note to Physicians:
Treat symptomatically.
No specific antidote.
Provide supportive care.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles or face shield, and protective clothing.
Use respiratory protection if ventilation is insufficient or if exposure limits are exceeded.

Ventilation:
Ensure adequate ventilation in the working area to control airborne concentrations below occupational exposure limits.
Use local exhaust ventilation or other engineering controls to minimize exposure.

Avoidance:
Avoid direct skin contact and inhalation of vapors.
Do not eat, drink, or smoke while handling Ultramoll® VII.
Wash hands thoroughly after handling.

Spill and Leak Procedures:
Use appropriate personal protective equipment.
Contain spills to prevent further release and minimize exposure.
Absorb spills with inert materials (e.g., sand, vermiculite) and collect for disposal.

Storage:
Store Ultramoll® VII in a cool, well-ventilated area away from incompatible materials (see SDS for specific details).
Keep containers tightly closed when not in use to prevent contamination.
Store away from heat sources, direct sunlight, and ignition sources.

Handling Cautions:
Avoid generating aerosols or mists.
Ground and bond containers during transfer operations to prevent static electricity buildup.
Use explosion-proof electrical equipment in areas where vapors may be present.


Storage:

Temperature:
Store Ultramoll® VII at temperatures recommended by the manufacturer.
Avoid exposure to extreme temperatures.

Containers:
Use approved containers made of compatible materials.
Check for leaks or damage in storage containers regularly.

Separation:
Store Ultramoll® VII away from incompatible materials, including strong acids, bases, oxidizing agents, and reducing agents.

Handling Equipment:
Use dedicated equipment for handling Ultramoll® VII to avoid cross-contamination.
Ensure all handling equipment is in good condition.

Security Measures:
Restrict access to storage areas.
Follow all applicable local regulations regarding the storage of hazardous materials.

Emergency Response:
Have emergency response equipment and materials readily available, including spill cleanup materials, fire extinguishers, and emergency eyewash stations.

UNDECANE
Undecanedioic Acid; 1,11-Undecanedioic acid; 1,9-Nonanedicarboxylic acid; Undecandiäure; ácido undecanodioico; Acide undécanedioïque; n-Nonane-omega,omega'-dicarboxylic acid; Undecane-1,11-dioic acid; CAS NO: 1852-04-6
Undecanedioic Acid
UNDECANOIC ACID N° CAS : 112-37-8 "Bien" dans toutes les catégories. Nom INCI : UNDECANOIC ACID Nom chimique : Undecanoic acid N° EINECS/ELINCS : 203-964-2 Ses fonctions (INCI) Anti-séborrhée : Aide à contrôler la production de sébum Agent nettoyant : Aide à garder une surface propre Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
UNDECANOIC ACID
UNDECETH-10; N° CAS : 34398-01-1; "Pas terrible" dans toutes les catégories.; Nom INCI : UNDECETH-10; Classification : Composé éthoxylé, Tensioactif non ionique Ses fonctions (INCI); Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation.Noms français : Éther de polyéthylène glycol (10) et d'undécyle ; Noms anglais : Poly(oxy-1,2-ethanediyl), alpha-undecyl-omega-hydroxy-
UNDECANOL
Undecanol, also known as N-undecyl alcohol or undecan-1-ol, belongs to the class of organic compounds known as fatty alcohols.
These are aliphatic alcohols consisting of a chain of a least six carbon atoms.
Thus, Undecanol is considered to be a fatty alcohol.

CAS Number: 112-42-5
EC Number: 203-970-5
Chemical Formula: CH3(CH2)10OH
Molar Mass: 172.31 g/mol

Undecanol, also known as N-undecyl alcohol or undecan-1-ol, belongs to the class of organic compounds known as fatty alcohols.
These are aliphatic alcohols consisting of a chain of a least six carbon atoms.

Thus, Undecanol is considered to be a fatty alcohol lipid molecule.
Undecanol is a very hydrophobic molecule, practically insoluble in water, and relatively neutral.

Undecanol is a colorless, water-insoluble liquid.
Undecanol has a floral citrus like odor, and a fatty taste and is used as a flavoring ingredient in foods.

Undecanol can be found in fruits including apples and bananas.
Undecanol is commonly produced by the reduction of 1-undecanal, the analogous aldehyde.

Undecanol, also known as Undecyl alcohol or 1-Hendecanol, is a fatty alcohol which can be found in foods like fruits, eggs, and cooked pork.
Ungraded products supplied by TCI America are generally suitable for common industrial uses or for research purposes but typically are not suitable for human consumption or therapeutic use.

Undecanol can be used as a precursor in the synthesis of undecanal by chemoselective oxidation using a fluorous derivative of TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) radical as a catalyst.
Undecanol can be also used as a solvent in homogeneous liquid-liquid microextraction method.

Undecanol, also known by its IUPAC name 1-undecanol or undecan-1-ol, and by Undecanol trivial names undecyl alcohol and hendecanol, is a fatty alcohol.
Undecanol is a colorless, water-insoluble liquid of melting point 19 °C and boiling point 243 °C.

Undecanol appears as a water-white liquid with a mild odor.
Flash point 250 °F.
Slightly soluble in water.

Considered a marine pollutant by DOT.
Immediate steps should be taken to limit Undecanol spread to the environment.

As a liquid Undecanol can easily penetrate the soil and contaminate groundwater or streams.
Mildly irritating to both the eyes and skin.

Undecanol is a fatty alcohol that is undecane substituted by a hydroxy group at position 1.
Undecanol has a role as a metabolite.
Undecanol is a fatty alcohol and a primary alcohol.

Uses of Undecanol:
Undecanol can be used as a precursor in the synthesis of undecanal by chemoselective oxidation using a fluorous derivative of TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) radical as a catalyst.
Undecanol can be also used as a solvent in homogeneous liquid-liquid microextraction method.

Consumer Uses:
Functional fluids (closed systems)
Intermediates
Processing aids, specific to petroleum production
Surface active agents

Industry Uses:
Functional fluids (closed systems)
Intermediate
Intermediates
Processing aids, specific to petroleum production
Surface active agents

Industrial Uses and Production of Undecanol:
Undecanol has a floral citrus like odor, and a fatty taste and is used as a flavoring ingredient in foods.
Undecanol is commonly produced by the reduction of undecanal, the analogous aldehyde.

General Manufacturing Information of Undecanol:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Oil and Gas Drilling, Extraction, and Support activities
Soap, Cleaning Compound, and Toilet Preparation Manufacturing

Natural Occurrence of Undecanol:
Undecanol is found naturally in many foods such as fruits (including apples and bananas), butter, eggs and cooked pork.

Pharmacology and Biochemistry of Undecanol:

Action Mechanism:
Undecanol was the most potent fungicide followed by decanol.
The time-kill curve study showed that undecanol was fungicidal against S. cerevisiae at any growth stages was not influenced by pH values.

The alcohols tested inhibited glucose-induced acidification by inhibiting the plasma membrane H(+)-ATPase.
The primary antifungal action of amphipathic medium-chain (C(9)-C(12)) alkanols comes mainly from their ability as nonionic surfactants to disrupt the native membrane-associated function of the integral proteins.

Human Metabolite Information of Undecanol:

Cellular Locations:
Extracellular
Membrane

Handling and Storage of Undecanol:

Nonfire Spill Response:
Do not touch or walk through spilled material.
Stop leak if you can do Undecanol without risk.

Prevent dust cloud.
For Asbestos, avoid inhalation of dust.

Cover spill with plastic sheet or tarp to minimize spreading.
Do not clean up or dispose of, except under supervision of a specialist.

SMALL DRY SPILL:
With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area.

SMALL SPILL:
Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Cover powder spill with plastic sheet or tarp to minimize spreading.
Prevent entry into waterways, sewers, basements or confined areas.

Fire Fighting of Undecanol:

SMALL FIRE:
Dry chemical, CO2, water spray or regular foam.

LARGE FIRE:
Water spray, fog or regular foam. Do not scatter spilled material with high-pressure water streams.
If Undecanol can be done safely, move undamaged containers away from the area around the fire.
Dike runoff from fire control for later disposal.

FIRE INVOLVING TANKS:
Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.
ALWAYS stay away from tanks engulfed in fire.

Accidental Release Measures of Undecanol:

IMMEDIATE PRECAUTIONARY MEASURE:
Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL:
Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Undecanol:

Personal protection:
Filter respirator for organic gases and vapours adapted to the airborne concentration of the substance.
Collect leaking and spilled liquid in covered containers as far as possible.

Cleanup Methods of Undecanol:
Using acclimated mixed microbial cultures, the theoretical and 5-day BOD for Undecanol were determined to be 16.50% and 4.5 mmol/mmol chemical, respectively.
After 5 days at 21 °C in sewage, the theoretical BOD for Undecanol was 27.6%.

Undecanol had a zero order biodegradation rate of 0.125 ppm/hour and a first order biodegradation rate constant of 6.1X10-3/hour by activated sludge.
Using this biodegradation rate constant a half-life of 4.7 days can be calculated.

Disposal Methods of Undecanol:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for its approved use or return Undecanol to the manufacturer or supplier.

Ultimate disposal of the chemical must consider:
The material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Safety Profile of Undecanol:
Moderately toxic by ingestion.
A skin irritant.

Combustible liquid.
Mutation data reported.
When heated to decomposition Undecanol emits acrid smoke and irritating fumes.

Identifiers of Undecanol:
CAS Number: 112-42-5
ChEBI: CHEBI:87499
ChEMBL: ChEMBL444525
ChemSpider: 7892
ECHA InfoCard: 100.003.609
PubChem CID: 8184
UNII: 06MJ0P28T3
CompTox Dashboard (EPA): DTXSID0026915
InChI: InChI=1S/C11H24O/c1-2-3-4-5-6-7-8-9-10-11-12/h12H,2-11H2,1H3
Key: KJIOQYGWTQBHNH-UHFFFAOYSA-N
SMILES: OCCCCCCCCCCC

CAS number: 112-42-5
EC number: 203-970-5
Hill Formula: C₁₁H₂₄O
Chemical formula: CH₃(CH₂)₁₀OH
Molar Mass: 172.31 g/mol
HS Code: 2905 19 00

Synonym(s): Alcohol C11, Undecyl alcohol
Linear Formula: CH3(CH2)10OH
CAS Number: 112-42-5
Molecular Weight: 172.31
Beilstein: 1698334
EC Number: 203-970-5
MDL number: MFCD00004751
PubChem Substance ID: 24900621
NACRES: NA.22

Product Number: U0005
Purity / Analysis Method: >99.0%(GC)
Molecular Formula / Molecular Weight: C11H24O = 172.31
Physical State (20 deg.C): Liquid
CAS RN: 112-42-5
Reaxys Registry Number: 1698334
PubChem Substance ID: 87577736
SDBS (AIST Spectral DB): 2531
MDL Number: MFCD00004751

Density: 0.83 g/mL at 25 °C
CAS No.: 112-42-5
Storage: 2 years -20°C liquid
Shipping: Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)
Smiles: CCCCCCCCCCCO

CAS: 1653-30-1
Molecular Formula: C11H24O
Molecular Weight (g/mol): 172.31
MDL Number: MFCD00021958
InChI Key: XMUJIPOFTAHSOK-UHFFFAOYNA-N
PubChem CID: 15448
ChEBI: CHEBI:77930
IUPAC Name: undecan-2-ol
SMILES: CCCCCCCCCC(C)O

Properties of Undecanol:
Chemical formula: C11H24O
Molar mass: 172.31 g/mol
Appearance: Colorless liquid
Density: 0.8298 g/mL
Melting point: 19 °C (66 °F; 292 K)
Boiling point: 243 °C (469 °F; 516 K)
Solubility in water: Insoluble
Solubility in Ethanol and diethyl ether: Soluble

Density: 0.83 g/cm3 (20 °C)
Flash point: 108 °C
Melting Point: 16 °C
Vapor pressure: Viscosity kinematic: 20.03 mm2/s (20 °C)
Solubility: 0.0057 g/l insoluble

Physical State: Liquid
Storage: Store at 4° C
Melting Point: 11° C (lit.)
Boiling Point: 146° C (lit.) at 30 mmHg
Density: 0.83 g/cm3 at 25° C

Quality Level: 100
Assay: 99%
Refractive index: n20/D 1.44 (lit.)
bp: 146 °C/30 mmHg (lit.)
mp: 11 °C (lit.)
Density: 0.83 g/mL at 25 °C (lit.)
Storage temp.: 2-8°C
SMILES string: CCCCCCCCCCCO
InChI: 1S/C11H24O/c1-2-3-4-5-6-7-8-9-10-11-12/h12H,2-11H2,1H3
InChI key: KJIOQYGWTQBHNH-UHFFFAOYSA-N

Molecular Weight: 172.31
XLogP3: 4.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 9
Exact Mass: 172.182715385
Monoisotopic Mass: 172.182715385
Topological Polar Surface Area: 20.2 Ų
Heavy Atom Count: 12
Complexity: 71.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Undecanol:
Assay (GC, area%): ≥ 97.5 % (a/a)
Density (d 20 °C/ 4 °C): 0.832 - 0.833
Identity (IR): passes test

Melting Point: 1°C to 3°C
Density: 0.828
Boiling Point: 228°C to 229°C
Flash Point: 107°C (225°F)
Odor: Mild
Beilstein: 1719795
Refractive Index: 1.437
Quantity: 50 g
Solubility Information: Not miscible or difficult to mix in water. Soluble in alcohol and ethyl ether.
Formula Weight: 172.31
Percent Purity: ≥98%
Chemical Name or Material: 2-Undecanol

Solubility: (20 °C) insoluble
Melting Point: 13 - 15 °C
Molar Mass: 172.31 g/mol
Boiling Point: 129 - 131 °C (16 hPa)
Flash Point: 113 °C
Refractive Index: 1.44 (20 °C, 589 nm)
Density: 0.83 g/cm3 (20 °C)
pH: 7 (H2O, 20 °C)
Synonyms: Undecyl alcohol
Hill Formula: C11H24O
Chemical Formula: CH3(CH2)10OH

Related Products of Undecanol:
N,N-Diethyl-2,2,2-trifluoroacetamide
1-Bromo-2,4-difluoro-3-methylbenzene
(2,3-Difluoro-4-methylphenyl)methanol
a-Hydroxy-γ-butyrolactone
3-Isobutylaniline

Names of Undecanol:

Preferred IUPAC name:
Undecan-1-ol

Other names:
Undecanol
1-Undecanol
Undecyl alcohol
1-Hendecanol

Synonyms of Undecanol:
1-UNDECANOL
Undecan-1-ol
Undecyl alcohol
112-42-5
Undecanol
n-Undecanol
n-Undecyl alcohol
1-Hendecanol
Hendecanoic alcohol
Hendecyl alcohol
Alcohol C-11
n-Hendecylenic alcohol
Tip-Nip
1-Undecyl alcohol
n-Undecan-1-ol
Decyl carbinol
C11 alcohol
Neodol 1
FEMA No. 3097
Alcohol C11
Undecanol-(1)
NSC 403667
CHEBI:87499
06MJ0P28T3
NSC-403667
Alcohol, undecyl
CAS-112-42-5
UMQ
UNA
HENDECANOL
HSDB 1089
EINECS 203-970-5
BRN 1698334
Decane, hydroxymethyl deriv.
UNII-06MJ0P28T3
AI3-00330
Neoflex 11
Pri-n-undecyl alcohol
1-Undecanol, 99%
Dlcohol c-11 undecylic
EC 203-970-5
1-UNDECANOL [HSDB]
SCHEMBL20655
n-C11H23OH
Undecyl alcohol, 97%, FG
4-01-00-01835 (Beilstein Handbook Reference)
UNDECYL ALCOHOL [FCC]
UNDECYL ALCOHOL [FHFI]
UNDECYL ALCOHOL [INCI]
CHEMBL444525
DTXSID0026915
AMY5947
ZINC1596062
Tox21_201585
Tox21_300548
LMFA05000144
MFCD00004751
NSC403667
s9450
STL280304
AKOS009031434
CS-W004292
HY-W004292
6-(methylamino)pyridin-3-ylboronic?acid
NCGC00164024-01
NCGC00164024-02
NCGC00164024-03
NCGC00254401-01
NCGC00259134-01
1-Undecanol, purum, >=98.0% (GC)
143819-62-9
BP-31088
LS-14031
FT-0608326
U0005
EN300-20041
Q161686
J-002774
F8881-3903
112-42-5 [RN]
1-Undecanol [ACD/Index Name] [ACD/IUPAC Name]
1-Undecanol [German] [ACD/Index Name] [ACD/IUPAC Name]
1-Undécanol [French] [ACD/IUPAC Name]
250-092-3 [EINECS]
30207-98-8 [RN]
MFCD00004751 [MDL number]
undecan-1-ol
Undecanol [Wiki]
Undecyl alcohol
YQ3155000
11-Undecanolactone
143819-62-9 [RN]
1-Hendecanol
1-Hydroxyundecane
1-UNDECANOL-D23
1-Undecyl alcohol
349553-88-4 [RN]
4-01-00-01835 (Beilstein Handbook Reference) [Beilstein]
Alcohol, undecyl
bovine albumin
Hendecanoic alcohol
hendecanol
Hendecyl alcohol
methyl butylhexanol
NCGC00164024-01
Neodol 1
Neoflex 11
n-Hendecylenic alcohol
n-Undecan-1-ol
n-Undecanol
N-UNDECYL ALCOHOL
n-Undecyl-d23 Alcohol
Pri-N-undecyl alcohol
pUndecanol
Tip-Ni
Tip-Nip
UMQ
UNA
Undecanol-(1)
UNDECYL-MALTOSIDE
UNDECETH-10 ( Éther de polyéthylène glycol (10) et d'undécyle)
Accueil Ingrédients UNDECETH-11 UNDECETH-11 Nom INCI : UNDECETH-11 Classification : Composé éthoxylé Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
UNDECETH-11
UNDECETH-3 Nom INCI : UNDECETH-3 Classification : Composé éthoxylé Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
UNDECETH-3
UNDECETH-5 N° CAS : 34398-01-1 Nom INCI : UNDECETH-5 Classification : Composé éthoxylé Ses fonctions (INCI) Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
UNDECETH-5
UNDECETH-8 "Pas terrible" dans toutes les catégories. Nom INCI : UNDECETH-8 Classification : Composé éthoxylé Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Agent d'entretien de la peau : Maintient la peau en bon état Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
UNDECETH-8
UNDECYL ALCOHOL N° CAS : 112-42-5 "Satisfaisant" dans toutes les catégories. Nom INCI : UNDECYL ALCOHOL Nom chimique : Undecan-1-ol N° EINECS/ELINCS : 203-970-5 Classification : Alcool Ses fonctions (INCI) Anti-séborrhée : Aide à contrôler la production de sébum Emollient : Adoucit et assouplit la peau Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit Agent d'entretien de la peau : Maintient la peau en bon état Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
UNDECYL ALCOHOL
Alphadrate; Amide of carbonic acid; Carbamimidic acid; Carbamide resin; Carbamimidic acid; Carbonyl diamide; Carbonyldiamine; Isourea cas no: 57-13-6
UNDECYL ALCOHOL
Undecyl alcohol 97%, FG Synonym: 1-Undecanol, Alcohol C11, Undecyl alcohol CAS Number 112-42-5 Linear Formula CH3(CH2)10OH Molecular Weight 172.31 FEMA Number 3097 Beilstein/REAXYS Number 1698334 EC Number 203-970-5 Council of Europe no. 751 MDL number MFCD00004751 PubChem Substance ID 24901463 Flavis number 2.057 NACRES NA.21 Undecyl alcohol has been reported as a key volatile constituent of Senecio tenuifolius and Flacourtia montana. Undecanol, also known by its IUPAC name 1-undecanol or undecan-1-ol, and by its trivial names undecyl alcohol and hendecanol, is a fatty alcohol. Undecanol is a colorless, water-insoluble liquid of melting point 19 °C and boiling point 243 °C. It has a floral citrus like odor, and a fatty taste and is used as a flavoring ingredient in foods. It is commonly produced by the reduction of undecanal, the analogous aldehyde. 1-Undecanol is found naturally in many foods such as fruits (including apples and bananas), butter, eggs and cooked pork. Undecanol can irritate the skin, eyes and lungs. Ingestion can be harmful, with the approximate toxicity of ethanol. 1-undecanol appears as a water-white liquid with a mild odor. Flash point 250°F. Slightly soluble in water. Considered a marine pollutant by DOT. Immediate steps should be taken to limit its spread to the environment. As a liquid it can easily penetrate the soil and contaminate groundwater or streams. Mildly irritating to both the eyes and skin.COLOURLESS LIQUID.Citrus.FATTY FLAVOR.473 °F at 760 mm Hg.Soluble in ethanol; very soluble in ether.Soluble in 60% alcohol.When heated to decomposition it emit acrid smoke and irritating fumes..Undecanol was the most potent fungicide followed by decanol. The time-kill curve study showed that undecanol was fungicidal against S. cerevisiae at any growth stages was not influenced by pH values. The alcohols tested inhibited glucose-induced acidification by inhibiting the plasma membrane H(+)-ATPase. The primary antifungal action of amphipathic medium-chain (C(9)-C(12)) alkanols comes mainly from their ability as nonionic surfactants to disrupt the native membrane-associated function of the integral proteins. Industry Uses Functional fluids (closed systems) Processing aids, specific to petroleum production Surface active agents Consumer Uses Fuels and related products Laundry and dishwashing products Personal care products By reduction of the corresponding aldehyde.Purity: a minimum of 97-98.5% undecyl alcohol.This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and/or 1994. The HPV list is based on the 1990 Inventory Update Rule.Commercial products from the family of 6 to 11 carbon alcohols that make up the plasticizer range are available both as ... pure single carbon chain materials and as complex isomeric mixtures. Commercial descriptions of plasticizer range alcohols are ... in general a ... pure material is called "-anol" /eg, 1-undecanol/, and the mixtures are called "-yl alcohol /eg, undecyl alcohol/ or "iso...yl alcohol" /eg, isoundecyl alcohol/.Reported uses /include/ non-alcoholic beverages 4.09 ppm; ice cream, ices, etc 15.47 ppm; candy 17.65 ppm; baked goods 17.66 ppm; alcoholic beverages 4.50 ppm.Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot. For UN3508, be aware of possible short circuiting as this product is transported in a charged state.Wash eyes with water for at least 15 min.Fresh air, rest. Refer for medical attention.Remove contaminated clothes. Rinse and then wash skin with water and soap.First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: SMALL FIRE: Dry chemical, CO2, water spray or regular foam. LARGE FIRE: Water spray, fog or regular foam. Do not scatter spilled material with high-pressure water streams. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal. FIRE INVOLVING TANKS: Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire.Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in covered containers as far as possible.Using acclimated mixed microbial cultures, the theoretical and 5-day BOD for 1-undecanol were determined to be 16.50% and 4.5 mmol/mmol chemical, respectively(1). After 5 days at 21 °C in sewage, the theoretical BOD for 1-undecanol was 27.6%(2). 1-Undecanol had a zero order biodegradation rate of 0.125 ppm/hour and a first order biodegradation rate constant of 6.1X10-3/hour by activated sludge(3). Using this biodegradation rate constant a half-life of 4.7 days can be calculated.The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]: Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent dust cloud. Avoid inhalation of asbestos dust. SMALL DRY SPILL: With clean shovel, place material into clean, dry container and cover loosely; move containers from spill area. SMALL SPILL: Pick up with sand or other non-combustible absorbent material and place into containers for later disposal. LARGE SPILL: Dike far ahead of liquid spill for later disposal. Cover powder spill with plastic sheet or tarp to minimize spreading. Prevent entry into waterways, sewers, basements or confined areas. (ERG, 2016)Residues of nonyl, decyl, and undecyl glycoside mixture with a mixture of nonyl, decyl, and undecyl oligosaccharides and related reaction products (primarily decanol and undecanol) produced as an aqueous-based liquid (50 to 65% solids) from the reaction of primary alcohols (containing 15 to 20% secondary alcohol isomers) in a ratio of 20% C9, 40% C10, and 40% C11 with carbohydrates (average glucose to alkyl chain ratio 1.3 to 1.8) are exempted from the requirement of a tolerance when used as a surfactant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.Residues of nonyl, decyl, and undecyl glycoside mixture with a mixture of nonyl, decyl, and undecyl oligosaccharides and related reaction products (primarily decanol and undecanol) produced as an aqueous-based liquid (50 to 65% solids) from the reaction of primary alcohols (containing 15 to 20% secondary alcohol isomers) in a ratio of 20% C9, 40% C10, and 40% C11 with carbohydrates (average glucose to alkyl chain ratio 1.3 to 1.8) are exempted from the requirement of a tolerance when used as a surfactant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to animals.UNDECANOL is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.Residues of nonyl, decyl, and undecyl glycoside mixture with a mixture of nonyl, decyl, and undecyl oligosaccharides and related reaction products (primarily decanol and undecanol) produced as an aqueous-based liquid (50 to 65% solids) from the reaction of primary alcohols (containing 15 to 20% secondary alcohol isomers) in a ratio of 20% C9, 40% C10, and 40% C11 with carbohydrates (average glucose to alkyl chain ratio 1.3 to 1.8) are exempted from the requirement of a tolerance when used as a surfactant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.Residues of nonyl, decyl, and undecyl glycoside mixture with a mixture of nonyl, decyl, and undecyl oligosaccharides and related reaction products (primarily decanol and undecanol) produced as an aqueous-based liquid (50 to 65% solids) from the reaction of primary alcohols (containing 15 to 20% secondary alcohol isomers) in a ratio of 20% C9, 40% C10, and 40% C11 with carbohydrates (average glucose to alkyl chain ratio 1.3 to 1.8) are exempted from the requirement of a tolerance when used as a surfactant in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to animals.Undecyl alcohol is a food additive permitted for direct addition to food for human consumption as a synthetic flavoring substance and adjuvant in accordance with the following conditions: a) they are used in the minimum quantity required to produce their intended effect, and otherwise in accordance with all the principles of good manufacturing practice, and 2) they consist of one or more of the following, used alone or in combination with flavoring substances and adjuvants generally recognized as safe in food, prior-sanctioned for such use, or regulated by an appropriate section in this part.ALCOHOL-INDUCED NUTRITIONAL ENCEPHALOMALACIA IN STARTING CHICKS COULD BE COMPLETELY PREVENTED BY DIETARY SUPPLEMENTATION OF D,L-ALPHA-TOCOPHERYL ACETATE.WITH USE OF SURFACTANTS EG TWEEN 80, ALCOHOL EMULSIONS WERE PHYTOTOXIC ONLY TO YOUNG MERISTEMATIC TISSUE. WITHOUT THE SURFACANT, C11 ALCOHOLS & ESTERS SHOWED NONSELECTIVE TISSUE KILL.Basic Treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Monitor for pulmonary edema and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Higher alcohols (>3 carbons) and related compounds/Advanced Treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques, with a bag-valve-mask device, may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if patient is hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Monitor for signs of hypoglycemia (decreased LOC, tachycardia, pallor, dilated pupils, diaphoresis, and/or dextrose strip or glucometer readings below 50 mg) and administer 50% dextrose if necessary ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Higher alcohols (>3 carbons) and related compounds//SIGNS AND SYMPTOMS/ The substance is severely irritating to the eyes, and is irritating to the skin and the respiratory tract.1-Undecanol's production and use as a food additive, synthetic flavor, and in perfumery may result in its release to the environment through various waste streams. 1-Undecanol exists naturally in citrus fruits. If released to air, a vapor pressure of 2.97X10-3 mm Hg at 25 °C indicates 1-undecanol will exist solely as a vapor in the atmosphere. Vapor-phase 1-undecanol will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 23 hours. If released to soil, 1-undecanol is expected to have no mobility based upon an estimated Koc of 8,800. Volatilization from moist soil surfaces is expected to be an important fate process based upon an estimated Henry's Law constant of 7.3X10-5 atm-cu m/mole. However, adsorption to soil is expected to attenuate volatilization. 1-Undecanol is expected to biodegrade rapidly in soil and water based on sewage and sludge studies. If released into water, 1-undecanol is expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant. Estimated volatilization half-lives for a model river and model lake are 20 hours and 10 days, respectively. However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 9 months if adsorption is considered. An estimated BCF of 86 suggests the potential for bioconcentration in aquatic organisms is moderate. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to 1-undecanol may occur through dermal contact with this compound at workplaces where 1-undecanol is produced or used. Monitoring data indicate that the general population may be exposed to 1-undecanol via ingestion of food and drinking water, and dermal contact with this compound and other consumer products containing 1-undecanol. (SRC)TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 8,800(SRC), determined from a log Kow of 4.72(2) and a regression-derived equation(3), indicates that 1-undecanol is expected to be immobile in soil(SRC). Volatilization of 1-undecanol from moist soil surfaces is expected to be an important fate process(SRC) given an estimated Henry's Law constant of 7.3X10-5 atm-cu m/mole(SRC), using a fragment constant estimation method(4). However, adsorption to soil is expected to attenuate volatilization(SRC). 1-Undecanol is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 2.97X10-3 mm Hg(5). The theoretical BOD for 1-undecanol was 27.6% after 5-day incubation in sewage(6), indicating that biodegradation may be an important environmental fate process in soil(SRC).AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 8,800(SRC), determined from a log Kow of 4.72(2) and a regression-derived equation(3), indicates that 1-undecanol is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is expected(3) based upon an estimated Henry's Law constant of 7.3X10-5 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). Using this Henry's Law constant and an estimation method(3), volatilization half-lives for a model river and model lake are 20 hours and 10 days, respectively(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The estimated volatilization half-life from a model pond is 9 months if adsorption is considered(5). According to a classification scheme(6), an estimated BCF of 86(SRC), from its log Kow(2) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is moderate(SRC). The theoretical BOD for 1-undecanol was 27.6% after 5-day incubation in sewage(8), indicating that biodegradation may be an important environmental fate process in water(SRC).ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), 1-undecanol, which has a vapor pressure of 2.97X10-3 mm Hg at 25 °C(2), is expected to exist solely as a vapor in the ambient atmosphere. Vapor-phase 1-undecanol is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals(SRC); the half-life for this reaction in air is estimated to be 23 hours(SRC), calculated from its rate constant of 1.7X10-11 cu cm/molecule-sec at 25 °C(SRC) that was derived using a structure estimation method(3).AEROBIC: Using acclimated mixed microbial cultures, the theoretical and 5-day BOD for 1-undecanol were determined to be 16.50% and 4.5 mmol/mmol chemical, respectively(1). After 5 days at 21 °C in sewage, the theoretical BOD for 1-undecanol was 27.6%(2). 1-Undecanol had a zero order biodegradation rate of 0.125 ppm/hour and a first order biodegradation rate constant of 6.1X10-3/hour by activated sludge(3). Using this biodegradation rate constant a half-life of 4.7 days can be calculated(SRC).The rate constant for the vapor-phase reaction of 1-undecanol with photochemically-produced hydroxyl radicals has been estimated as 1.7X10-11 cu cm/molecule-sec at 25 °C(SRC) using a structure estimation method(1). This corresponds to an atmospheric half-life of about 23 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(1). 1-Undecanol is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(2).An estimated BCF of 86 was calculated for 1-undecanol(SRC), using a log Kow of 4.72(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is moderate(SRC), provided the compound is not metabolized by the organism(SRC).The Koc of 1-undecanol is estimated as 8,800(SRC), using a log Kow of 4.72(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 1-undecanol is expected to be immobile in soil.The Henry's Law constant for 1-undecanol is estimated as 7.23X10-5 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that 1-undecanol is expected to volatilize from water surfaces(2). Based on this Henry's Law constant, the volatilization half-life from a model river (1 m deep, flowing 1 m/sec, wind velocity of 3 m/sec)(2) is estimated as 20 hours(SRC). The volatilization half-life from a model lake (1 m deep, flowing 0.05 m/sec, wind velocity of 0.5 m/sec)(2) is estimated as 10 days(SRC). 1-Undecanol's Henry's Law constant indicates that volatilization from moist soil surfaces may occur(SRC). However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column. The volatilization half-life from a model pond is about 9 months when adsorption is considered(3). 1-Undecanol is not expected to volatilize from dry soil surfaces(SRC) based upon a vapor pressure of 2.97X10-3 mm Hg(4).SURFACE WATER: 1-Undecanol has been qualitatively identified in the Northern Basin of Lake Michigan(1).1-Undecanol was identified as a volatile component of beef.1-Undecanol was qualitatively identified in Lake Michigan lake trout at Charlevoix, MI on 9/25/77(1).Occupational exposure to 1-undecanol may occur through dermal contact with this compound at workplaces where 1-undecanol is produced or used. Monitoring data indicate that the general population may be exposed to 1-undecanol via ingestion of food and drinking water, and dermal contact with this compound and other consumer products containing 1-undecanol. (SRC) UNDECYL ALCOHOL UNDECYL ALCOHOL is classified as : Antiseborrhoeic Emollient Masking Skin conditioning Viscosity controlling CAS Number 112-42-5 EINECS/ELINCS No: 203-970-5 COSING REF No: 80494 Chem/IUPAC Name: Undecan-1-ol FORMULA C11 H24 O MOLECULAR WEIGHT 172 CAS 112-42-5 EINECS 203-970-5 FEMA 3097 APPEARANCE AT 20°C CLEAR MOBILE LIQUID / SOLID COLOR COLORLESS TO PALE YELLOW ODOR CITRUS, MILD, SLIGHTLY FATTY-WAXY TASTE ALDEHIDIC, SOAPY, WAXY, SWEET OPTICAL ROTATION (°) 0 / 0 DENSITY AT 20°C (g/ml)) 0,823 - 0,843 REFRACTIVE INDEX nD20 1,4370 - 1,4430 FLASHPOINT (°C) 113 SOLUBILITY 1:1 v/v ETHANOL 80% ASSAY (% GC) > 98 ACID VALUE (mg KOH/g) < 3 Flavouring Undecyl alcohol Synonym(s) Alcohol C-11 Latest JECFA evaluation 1997 (Session 49) Status of specification Full Chemical name 1-Undecanol JECFA number 106 CAS number 112-42-5 FEMA number 3097 COE number 751 FLAVIS number - Molecular weight 172.31 Chemical formula C11H24O Physical form/odour colourless liquid/fatty-floral odour Solubility soluble in most fixed oils; insoluble in water Solubility in ethanol 1ml in 4 ml of 60% alcohol Boiling point (°C) 146° (30 mm Hg) Assay min % 97.0% Acid value max - Refractive index 1.437-1.443 Specific gravity 0.820-0.840 Other requirements - ID Test IR 1-undecanol, being an organic chemical with molecular formula C11H24O and scented with lemon, is a colorless or pale yellow , water insoluble but alcohol and ether soluble liquid. It is prepared from metal sodium reduction of Ethyl undecanoate, or pressurization and catalytic hydrogenation of ethyl ω- undecanoate , or even obtained by the Grignard reaction of nonyl magnesium bromide and with ethylene oxide. The application of this alcohol is limited. It is only used for some typical aroma oil and fragrance as the fat is solid at low temperature. The citrus rose type and the like only play a secondary and harmonious role and are taken as deodorant. In addition, it is also used to manufacture spices with the scent of acacia, polianthes tuberosa and the like.It is colorless liquid at room temperature; scented with light sweet fat wax mixed with the scent of roses and fruity flavor of citrus, pineapple and the like. But generally the whole body smells scent of rose, as if a little bit of rue flavor. It will smell like orange after highly diluted with the soft sweet flavor of citrus fruit oil. Its concentration is less than 20 × 10-6 with fruity and sweet scent. Unpleasant fat and smell will be produced when the concentration is higher; Melting point :15 ~ 19 ℃; Flash point> 82 ℃; Density: D4250 .828 ~ 0.834; Refractive index: nD200.4370 ~ 1.4430; water insoluble, soluble in most organic solvents, 1: 4.soluble in 60% ethanol.It is prepared from undecaethylene reduction. Put 200 ml of anhydrous toluene and 70 g of sodium into a 5-liter three-necked flask, and then heat reflux it until sodium is completely melted. Then stop heating, stir quickly to get the sodium to disperse into sand until the temperature drops to 60 ~ C. Then put 107 grams of ethyl undecanoate into 150ml absolute ethanol solution followed by adding 500ml of absolute ethanol. When the reaction is weakened, heat it in an oil bath until the sodium is completely dissolved. Next remove the ethanol and toluene through the method of steam distillation. Then wash the remaining oily substances with 200ml × 3 hot water. Then wash ether layer with a sequence of water, sodium carbonate and then water after the ethyl ether was extracted. Also dry with magnesium sulfate, boil off the ethyl ether. The product will be finally extracted from the residue after reduced pressure distillation. The yield is 70%. Uses Although this undecanol is among the common varieties, but it is still not widely used. It is often used together with undecylenic aldenyde or other fat and aldehydes as the integrator of fragrant volatile of aldehyde. Also it can be well integrated with floral fragrance, citrus cologne, acacia, robinia pseudoacacia, tuberose, violets, clean and grass smell, usually used for rose base. Few application is also available in such pineapple, orange, lemon, lime, orange , cassis, rose food flavors. Storage Be sealed and stored in a cool dry place. Also be kept away from fire. Chemical Properties Colorless liquid; citrus odor. Soluble in 60% alcohol. Combustible. Chemical Properties Undecyl alcohol has a floral, citrus-like odor and fatty flavor. Occurrence Reported found in citrus fruits, fresh apple, banana, sour cherry, orange juice, orange peel oil, American cranberry, Vitis vinifera L., parmesan cheese, mushroom, tamarind, coriander seed and leaf, white wine, butter, heated butter, boiled eggs, boiled or uncured pork, plum brandy, coriander leaf, crayfish and oysters. Uses 1-Undecanol is an antifungal, antioxidant compound. As well, it is used in the synthesis Definition ChEBI: A fatty alcohol that is undecane substituted by a hydroxy group at position 1. Preparation By reduction of the corresponding aldehyde. Synthesis Reference(s) The Journal of Organic Chemistry, 60, p. 5961, 1995 DOI: 10.1021/jo00123a038 Health Hazard Recommended Personal Protective Equipment: Goggles and face shield; Symptoms Following Exposure: Liquid can irritate eyes; General Treatment for Exposure: Wash eyes with water for at least 15 min.; Toxicity by Inhalation (Threshold Limit Value): Not pertinent; Short-Term Exposure Limits: Not pertinent; Toxicity by Ingestion: Grade 2, LD50 = 0.5-5 g/kg; Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: None; Liquid or Solid Irritant Characteristics: No appreciable hazard. Practically harmless to the skin; Odor Threshold: Not pertinent. Chemical Reactivity Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent. Safety Profile Moderately toxic by ingestion. A skin irritant. Combustible liquid. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALCOHOLS. Metabolism See alcohol C-8. Purification Methods Purify the alcohol by repeated fractional crystallisation from its melt or by distillation in a vacuum. [Beilstein 1 H 427, 1 IV 1835.] 1-Undecanol, also known as N-undecyl alcohol or undecan-1-ol, belongs to the class of organic compounds known as fatty alcohols. These are aliphatic alcohols consisting of a chain of a least six carbon atoms. Thus, 1-undecanol is considered to be a fatty alcohol lipid molecule. 1-Undecanol is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral. Higher alcohols are not highly toxic in the industrial setting; Can cause liver injury, somnolence, and respiratory depression in experimental animals; A skin, eye, and respiratory tract irritant; [HSDB] Safe when used as a flavoring agent in food; [JECFA] An irritant; [MSDSonline] 1-Undecanol Formula: C11H24O Molecular weight: 172.3077 IUPAC Standard InChI: InChI=1S/C11H24O/c1-2-3-4-5-6-7-8-9-10-11-12/h12H,2-11H2,1H3 Download the identifier in a file. INChI Trust 2011 Certified Logo IUPAC Standard InChIKey: KJIOQYGWTQBHNH-UHFFFAOYSA-N CAS Registry Number: 112-42-5 Chemical structure: C11H24O This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Other names: Undecyl alcohol; n-Undecan-1-ol; n-Undecanol; n-Undecyl alcohol; Hendecanoic alcohol; Hendecyl alcohol; 1-Hendecanol; Alcohol c-11; n-Hendecylenic alcohol; Undecanol-(1); Tip-Nip; Undecanol; Decyl carbinol; Neodol 1; Undecan-1-ol; 1-Undecyl alcohol; NSC 403667 Permanent link for this species. Use this link for bookmarking this species for future reference. Information on this page: Reaction thermochemistry data References Notes Other data available: Condensed phase thermochemistry data Phase change data IR Spectrum Mass spectrum (electron ionization) Gas Chromatography Options: Switch to calorie-based units
UNDECYL ALCOHOL (UNDECANOL)
Undecyl alcohol (undecanol), being an organic chemical with molecular formula C11H24O and scented with lemon, is a colorless or pale yellow , water insoluble but alcohol and ether soluble liquid.
Undecyl alcohol (undecanol) is prepared from metal sodium reduction of Ethyl undecanoate, or pressurization and catalytic hydrogenation of ethyl ω- undecanoate , or even obtained by the Grignard reaction of nonyl magnesium bromide and with ethylene oxide.
The application of this alcohol is limited.

CAS: 112-42-5
MF: C11H24O
MW: 172.31
EINECS: 203-970-5

Undecyl alcohol (undecanol) is only used for some typical aroma oil and fragrance as the fat is solid at low temperature.
The citrus rose type and the like only play a secondary and harmonious role and are taken as deodorant.
In addition, Undecyl alcohol (undecanol) is also used to manufacture spices with the scent of acacia, polianthes tuberosa and the like.
A fatty alcohol that is undecane substituted by a hydroxy group at position 1.
Undecyl alcohol (undecanol) appears as a water-white liquid with a mild odor. Flash point 250 °F.
Slightly soluble in water.
Considered a marine pollutant by DOT.
Immediate steps should be taken to limit its spread to the environment.
As a liquid Undecyl alcohol (undecanol) can easily penetrate the soil and contaminate groundwater or streams.
Mildly irritating to both the eyes and skin.
Undecyl alcohol (undecanol), also known by its IUPAC name 1-undecanol or undecan-1-ol, and by its trivial names undecyl alcohol and hendecanol, is a fatty alcohol.
Undecyl alcohol (undecanol) is a colorless, water-insoluble liquid of melting point 19 °C and boiling point 243 °C.

Undecyl alcohol (undecanol) Chemical Properties
Melting point: 11 °C (lit.)
Boiling point: 146 °C/30 mmHg (lit.)
Density: 0.83 g/mL at 25 °C (lit.)
Vapor pressure: <1 hPa (20 °C)
FEMA: 3097 | UNDECYL ALCOHOL
Refractive index: n20/D 1.44(lit.)
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: 0.0057g/l insoluble
Form: Liquid
Pka: 15.20±0.10(Predicted)
Color: Clear colorless to pale yellow
Odor: Faint alcohol.
Odor Type: waxy
Water Solubility: Not miscible or difficult to mix with water. Soluble in chloroform and ethyl acetate.
JECFA Number: 106
BRN: 1698334
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong acids.
LogP: 4.9 at 20℃
CAS DataBase Reference: 112-42-5(CAS DataBase Reference)
EPA Substance Registry System: Undecyl alcohol (undecanol) (112-42-5)

Undecyl alcohol (undecanol) is colorless liquid at room temperature; scented with light sweet fat wax mixed with the scent of roses and fruity flavor of citrus, pineapple and the like.
But generally the whole body smells scent of rose, as if a little bit of rue flavor.
Undecyl alcohol (undecanol) will smell like orange after highly diluted with the soft sweet flavor of citrus fruit oil.
Undecyl alcohol (undecanol)'s concentration is less than 20 × 10-6 with fruity and sweet scent.

Unpleasant fat and smell will be produced when the concentration is higher; Melting point :15 ~ 19 ℃; Flash point> 82 ℃; Density: D4250 .828 ~ 0.834; Refractive index: nD200.4370 ~ 1.4430; water insoluble, soluble in most organic solvents, 1: 4.soluble in 60% ethanol
Undecyl alcohol (undecanol) has a floral, citrus-like odor and fatty flavor.
Undecyl alcohol (undecanol) is an antifungal, antioxidant compound.
As well, Undecyl alcohol (undecanol) is used in the synthesis
Undecyl alcohol (undecanol) can be used as a precursor in the synthesis of undecanal by chemoselective oxidation using a fluorous derivative of TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl) radical as a catalyst.
Undecyl alcohol (undecanol) can be also used as a solvent in homogeneous liquid-liquid microextraction method.

Uses
Although Undecyl alcohol (undecanol) is among the common varieties, but it is still not widely used.
Undecyl alcohol (undecanol) is often used together with undecylenic aldenyde or other fat and aldehydes as the integrator of fragrant volatile of aldehyde.
Also Undecyl alcohol (undecanol) can be well integrated with floral fragrance, citrus cologne, acacia, robinia pseudoacacia, tuberose, violets, clean and grass smell, usually used for rose base.
Few application is also available in such pineapple, orange, lemon, lime, orange , cassis, rose food flavors.
Undecyl alcohol (undecanol) has a floral citrus like odor, and a fatty taste and is used as a flavoring ingredient in foods.
Undecyl alcohol (undecanol) is commonly produced by the reduction of undecanal, the analogous aldehyde.

Preparation
Undecyl alcohol (undecanol) is prepared from undecaethylene reduction.
Put 200 ml of anhydrous toluene and 70 g of sodium into a 5-liter three-necked flask, and then heat reflux Undecyl alcohol (undecanol) until sodium is completely melted.
Then stop heating, stir quickly to get the sodium to disperse into sand until the temperature drops to 60 ~ C.
Then put 107 grams of ethyl undecanoate into 150ml absolute ethanol solution followed by adding 500ml of absolute ethanol.
When the reaction is weakened, heat Undecyl alcohol (undecanol) in an oil bath until the sodium is completely dissolved.

Next remove the ethanol and toluene through the method of steam distillation.
Then wash the remaining oily substances with 200ml × 3 hot water.
Then wash ether layer with a sequence of water, sodium carbonate and then water after the ethyl ether was extracted.
Also dry with magnesium sulfate, boil off the ethyl ether.
Undecyl alcohol (undecanol) will be finally extracted from the residue after reduced pressure distillation.
The yield is 70%.

Health Hazard
Recommended Personal Protective Equipment: Goggles and face shield; Symptoms Following Exposure: Liquid can irritate eyes; General Treatment for Exposure: Wash eyes with water for at least 15 min.; Toxicity by Inhalation (Threshold Limit Value): Not pertinent; Short-Term Exposure Limits: Not pertinent; Toxicity by Ingestion: Grade 2, LD50 = 0.5-5 g/kg; Late Toxicity: Data not available; Vapor (Gas) Irritant Characteristics: None; Liquid or Solid Irritant Characteristics: No appreciable hazard.
Practically harmless to the skin; Odor Threshold: Not pertinent.
Undecyl alcohol (undecanol) can irritate the skin, eyes and lungs.
Ingestion can be harmful, with the approximate toxicity of ethanol.

Synonyms
1-UNDECANOL
Undecan-1-ol
Undecyl alcohol
112-42-5
Undecanol
n-Undecanol
n-Undecyl alcohol
1-Hendecanol
Hendecanoic alcohol
Hendecyl alcohol
Alcohol C-11
n-Hendecylenic alcohol
Tip-Nip
1-Undecyl alcohol
n-Undecan-1-ol
Decyl carbinol
C11 alcohol
Neodol 1
FEMA No. 3097
Alcohol, undecyl
Alcohol C11
Undecanol-(1)
NSC 403667
HSDB 1089
EINECS 203-970-5
BRN 1698334
Decane, hydroxymethyl deriv.
UNII-06MJ0P28T3
AI3-00330
DTXSID0026915
CHEBI:87499
06MJ0P28T3
NSC-403667
EC 203-970-5
4-01-00-01835 (Beilstein Handbook Reference)
DTXCID706915
143819-62-9
CAS-112-42-5
UMQ
UNA
HENDECANOL
Undcanol
1-Hydroxyundecane
Neoflex 11
Alchem 11
Undecan- 1- ol
Pri-n-undecyl alcohol
undecan - 1 - ol
C(CCCCC)CCCCCO
1-Undecanol, 99%
Dlcohol c-11 undecylic
1-UNDECANOL [HSDB]
SCHEMBL20655
n-C11H23OH
Undecyl alcohol, 97%, FG
Undecyl alcohol (6CI 8CI)
UNDECYL ALCOHOL [FCC]
UNDECYL ALCOHOL [FHFI]
UNDECYL ALCOHOL [INCI]
CHEMBL444525
AMY5947
Tox21_201585
Tox21_300548
LMFA05000144
MFCD00004751
NSC403667
s9450
STL280304
AKOS009031434
ALCOHOL C-11 (1-UNDECANOL)
CS-W004292
HY-W004292
LS-3149
6-(methylamino)pyridin-3-ylboronic?acid
NCGC00164024-01
NCGC00164024-02
NCGC00164024-03
NCGC00254401-01
NCGC00259134-01
1-Undecanol, purum, >=98.0% (GC)
BP-31088
FT-0608326
U0005
EN300-20041
Q161686
J-002774
F8881-3903
Z104476546
UNIPLEX FRP-45
DESCRIPTION:

UNIPLEX FRP-45 is Liquid flame retardant that imparts efficient flame retardance to a large number of polymers (e. g. flexible PVC, TPO, PU and elastomers) due to its high bromine content.
UNIPLEX FRP-45 offers a very low volatility combined with a superior thermal and color stability.


CAS# 26040-51-7
EC Number 247-426-5
Molecular Formula C24H34Br4O4
Molecular Weight 706.14

SYNONYMS OF UNIPLEX FRP-45:
FRP 45; Pyronil 45; Uniplex FRP 45, Di-(2-ethylhexyl) tetrabromophthalate


APPLICATIONS OF UNIPLEX FRP-45:
UNIPLEX FRP-45 is especially recommended for applications like cable & wires or conveyer belts (e. g. made of PVC-P).
UNIPLEX FRP-45 is also suitable for adhesives, coatings, films and coated fabrics.
Product is compatible with PVC, PVC-P, flexible PUR, EPDM and PF.
Outstanding thermostability, good hydrolytic stability, and low volatility.


UNIPLEX FRP-45 is di-(2-ethylhexyl) tetrabromo phthalate.
UNIPLEX FRP-45 Acts as a flame retardant.
UNIPLEX FRP-45 offers a very low volatility combined with a superior thermal and color stability.

Due to its high bromine content, UNIPLEX FRP-45 can be used in number of polymers.
UNIPLEX FRP-45 is Compatible with flexible PVC, TPO and elastomers.

UNIPLEX FRP-45 is Suitable for use in cable & wires or conveyer belts (e.g. made of PVC-P).
Uniplex FRP-45 has a shelf life of at least 1 year.

UNIPLEX FRP-45 is a Di-2-ethylhexyl tetra bromo phthalate appearing as a clear amber liquid.
This liquid flame retardant imparts efficient flame retardance to commonly used polymers due to its high bromine content.
UNIPLEX FRP-45 provides low volatility and thermal and colour stability, finding application in adhesives, coatings, films, and coated fabrics.


UNIPLEX FRP-45 is a flame retardant.
UNIPLEX FRP-45 is di-(2-ethylhexyl) tetrabromo phthalate (bromine content is 45%).
UNIPLEX FRP-45 offers a very low volatility combined with a superior thermal and color stability.

UNIPLEX FRP-45 is compatible with a large number of polymers (e.g. flexible PVC, TPO and elastomers) due to its high bromine content.
UNIPLEX FRP-45 is suitable for adhesives.
UNIPLEX FRP-45 has a shelf life of at least 1 year.

UNIPLEX FRP-45 is a liquid flame retardant that imparts efficient flame retardance to a large number of polymers (e.g. flexible PVC, TPO and elastomers) due to its high bromine content.
UNIPLEX FRP-45 offers a very low volatility combined with a superior thermal and colour stability.
UNIPLEX FRP-45 is Di-(2-ethylhexyl) tetrabromo phthalate.

UNIPLEX FRP-45 is often used in the construction industry , electronics industry and polymer/rubber industry
UNIPLEX FRP-45 is a liquid flame retardant for polyvinyl chloride that provides excellent plasticizing properties, in addition to flame retardancy.

UNIPLEX FRP-45 provides the following advantages in polyvinyl chloride, as well as in other elastomers such as SBR, Neoprene, and EPDM:
UNIPLEX FRP-45 has High oxygen index values for efficient flame retardancy
UNIPLEX FRP-45 is Highly effective plasticization
UNIPLEX FRP-45 is Superior thermal and color stability
UNIPLEX FRP-45 has Low volatility
UNIPLEX FRP-45 has Excellent electrical properties

USES OF UNIPLEX FRP-45:
Bis(2-ethylhexyl) tetrabromophthalate is for use as a flame retardant and plasticizer in vinyl products.
UNIPLEX FRP-45 is also used as a flame retardant in wire and cable insulation, carpet backing, fabrics, wall coverings, adhesives, coatings and polyurethane foam.


CHEMICAL AND PHYSICAL PROPERTIES OF UNIPLEX FRP-45:
Appearance Clear amber liquid
Bromine content 45%
Assay > 95%
2-Ethylhexanol content < 0.3%
Tetrabromophthalic anhydride content < 0.1%
Acidity < 0.05 mEq/100 g
Water content < 0.1%
Colour, Gardner < 3#
Density at 20 °C 1.541 g/cm3
Viscosity at 25 °C 1595 mPa • s
Solubility Insoluble (3.3E-6 g/L) (25 ºC), Calc.*
Density 1.529±0.06 g/cm3 (20 ºC 760 Torr), Calc.*
CAS# 26040-51-7
EC Number 247-426-5
Molecular Formula C24H34Br4O4
Molecular Weight 706.14
Melting Point: -27°C (-16.6°F)
Boiling Point: >=300°C (572°F)
Flash Point: 207°C (404.6°F) closed cup
Auto-ignition: 370°C (698°F)
Solubility in Water: Slight


SAFETY INFORMATION ABOUT UNIPLEX FRP-45:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.
UNIPLEX FRX 44-94
DESCRIPTION:

UNIPLEX FRX 44-94 is Liquid flame retardant that imparts efficient flame retardance to a large number of polymers (e. g. flexible PVC, TPO, PU and elastomers) due to its high bromine content.
UNIPLEX FRX 44-94 offers a very low volatility combined with a superior thermal and color stability.


CAS# 26040-51-7
EC Number 247-426-5
Molecular Formula C24H34Br4O4
Molecular Weight 706.14

SYNONYMS OF UNIPLEX FRX 44-94:
FRP 45; Pyronil 45; Uniplex FRP 45, Di-(2-ethylhexyl) tetrabromophthalate


UNIPLEX FRX 44-94 is a nitrogen and phosphorous containing blend appearing as a white powder.
UNIPLEX FRX 44-94 provides ultraviolet stability, is non-hydroscopic, and forms an intumescent layer under heat and fire exposure.
UNIPLEX FRX 44-94 finds application in thermosets, polyolefin compounds, and paints and coatings.

UNIPLEX FRX 44-94 is a nitrogen (27%) and phosphorus (15.7%) blend.
UNIPLEX FRX 44-94 Acts as a flame retardant.
The blend forms an intumescent layer under heat and fire exposure.

UNIPLEX FRX 44-94 offers an excellent UV stability and is non-hydroscopic.
UNIPLEX FRX 44-94 can be processed at temperatures up to 225°C.

UNIPLEX FRX 44-94 is Compatible with thermosets and polyolefin compounds and suitable for paints and coatings.
UNIPLEX FRX 44-94 has a shelf life of at least 3 years.

UNIPLEX FRX 44-94 is a nitrogen and phosphorous containing blend appearing as a white powder.
UNIPLEX FRX 44-94 provides ultraviolet stability, is non-hydroscopic, and forms an intumescent layer under heat and fire exposure.
UNIPLEX FRX 44-94 finds application in thermosets, polyolefin compounds, and paints and coatings.



APPLICATIONS OF UNIPLEX FRX 44-94:
UNIPLEX FRX 44-94 is especially recommended for applications like cable & wires or conveyer belts (e. g. made of PVC-P).
UNIPLEX FRX 44-94 is also suitable for adhesives, coatings, films and coated fabrics.
Product is compatible with PVC, PVC-P, flexible PUR, EPDM and PF.
Outstanding thermostability, good hydrolytic stability, and low volatility.


UNIPLEX FRX 44-94 is di-(2-ethylhexyl) tetrabromo phthalate.
UNIPLEX FRX 44-94 Acts as a flame retardant.
UNIPLEX FRX 44-94 offers a very low volatility combined with a superior thermal and color stability.

Due to its high bromine content, UNIPLEX FRX 44-94 can be used in number of polymers.
UNIPLEX FRX 44-94 is Compatible with flexible PVC, TPO and elastomers.

UNIPLEX FRX 44-94 is Suitable for use in cable & wires or conveyer belts (e.g. made of PVC-P).
UNIPLEX FRX 44-94 has a shelf life of at least 1 year.

UNIPLEX FRX 44-94 is a Di-2-ethylhexyl tetra bromo phthalate appearing as a clear amber liquid.
This liquid flame retardant imparts efficient flame retardance to commonly used polymers due to its high bromine content.
UNIPLEX FRX 44-94 provides low volatility and thermal and colour stability, finding application in adhesives, coatings, films, and coated fabrics.


UNIPLEX FRX 44-94 is a flame retardant.
UNIPLEX FRX 44-94 is di-(2-ethylhexyl) tetrabromo phthalate (bromine content is 45%).
UNIPLEX FRX 44-94 offers a very low volatility combined with a superior thermal and color stability.

UNIPLEX FRX 44-94 is compatible with a large number of polymers (e.g. flexible PVC, TPO and elastomers) due to its high bromine content.
UNIPLEX FRX 44-94 is suitable for adhesives.
UNIPLEX FRX 44-94 has a shelf life of at least 1 year.

UNIPLEX FRX 44-94 is a liquid flame retardant that imparts efficient flame retardance to a large number of polymers (e.g. flexible PVC, TPO and elastomers) due to its high bromine content.
UNIPLEX FRX 44-94 offers a very low volatility combined with a superior thermal and colour stability.
UNIPLEX FRX 44-94 is Di-(2-ethylhexyl) tetrabromo phthalate.

UNIPLEX FRX 44-94 is often used in the construction industry , electronics industry and polymer/rubber industry
UNIPLEX FRX 44-94 is a liquid flame retardant for polyvinyl chloride that provides excellent plasticizing properties, in addition to flame retardancy.

UNIPLEX FRX 44-94 provides the following advantages in polyvinyl chloride, as well as in other elastomers such as SBR, Neoprene, and EPDM:
UNIPLEX FRX 44-94 has High oxygen index values for efficient flame retardancy
UNIPLEX FRX 44-94 is Highly effective plasticization
UNIPLEX FRX 44-94 is Superior thermal and color stability
UNIPLEX FRX 44-94 has Low volatility
UNIPLEX FRX 44-94 has Excellent electrical properties

USES OF UNIPLEX FRX 44-94:
Bis(2-ethylhexyl) tetrabromophthalate is for use as a flame retardant and plasticizer in vinyl products.
UNIPLEX FRX 44-94 is also used as a flame retardant in wire and cable insulation, carpet backing, fabrics, wall coverings, adhesives, coatings and polyurethane foam.


CHEMICAL AND PHYSICAL PROPERTIES OF UNIPLEX FRX 44-94:
Appearance Clear amber liquid
Bromine content 45%
Assay > 95%
2-Ethylhexanol content < 0.3%
Tetrabromophthalic anhydride content < 0.1%
Acidity < 0.05 mEq/100 g
Water content < 0.1%
Colour, Gardner < 3#
Density at 20 °C 1.541 g/cm3
Viscosity at 25 °C 1595 mPa • s
Solubility Insoluble (3.3E-6 g/L) (25 ºC), Calc.*
Density 1.529±0.06 g/cm3 (20 ºC 760 Torr), Calc.*
CAS# 26040-51-7
EC Number 247-426-5
Molecular Formula C24H34Br4O4
Molecular Weight 706.14
Melting Point: -27°C (-16.6°F)
Boiling Point: >=300°C (572°F)
Flash Point: 207°C (404.6°F) closed cup
Auto-ignition: 370°C (698°F)
Solubility in Water: Slight


SAFETY INFORMATION ABOUT UNIPLEX FRX 44-94:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





UREA
Alphadrate; Amide of carbonic acid; Carbamimidic acid; Carbamide resin; Carbamimidic acid; Carbonyl diamide; Carbonyldiamine; Isourea CAS NO:57-13-6
UREA PEROXIDE
URSOLIC ACID N° CAS : 77-52-1 "Bien" dans toutes les catégories. Nom INCI : URSOLIC ACID Nom chimique : Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)-; 3b-Hydroxyurs-12-en-28-oic Acid; Hydroxyursenoic acid N° EINECS/ELINCS : 201-034-0 Ses fonctions (INCI) Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit Agent d'entretien de la peau : Maintient la peau en bon état Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
URSOLIC ACID
VALERIC ACID N° CAS : 109-52-4 "Bien" dans toutes les catégories. Nom INCI : VALERIC ACID Nom chimique : Pentanoic Acid N° EINECS/ELINCS : 203-677-2 Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
UV STABILIZER
UV STABILIZER UV stabilizer General name of additives used to prevent degradation of organic coating films exposed to UV light. UV stabilizers are classified into two groups. UV stabilizers (also called as UV absorbers). They convert the absorbed UV energy into heat and this heat is then dissipated through the substrate. Benzophenones and benzotriazole derivatives are commonly used UV stabilizers. The other group is free radical scavengers. They act by trapping the free radicals formed by UV light and decompose these radicals along with themselves hereby suppress the degradation of coating. Hindered amine light stabilizers (HALS) are used as free radical scavengers. UV Stabilizers for Engineering PlasticsEngineering plastics like polyamides, polyesters, polycarbonates are majorly used for applications that demand long time U.V stabilization. This selection guide mainly deals with the query "which UV Stabilizer is ideal for which plastic"? This guide will familiarize you with various UV stabilizers used with these engineering plastics. You would be able to find out the functionalities of different UV stabilizers for different engineering plastics in demand. Also one can find the starting point formulations of polycarbonates, polyacetal polyoxymethylene, polyesters like PET & PBT and polyamides.By Pascal Xanthopoulos UV StabilizersUV Stabilizers for PolycarbonateUV Stabilizers for POMUV Stabilizers for PolyestersUV Stabilizers for Polyamides UV Stabilizers UV stabilizers combat the degradation that plastics can undergo under the effects of sunlight, UV rays, heat and reaction with oxygen. The changes witnessed in a plastic can range from discoloration to formation of cracks. Incorporating a UV stabilizer into the polymer mix, improves the appearance/aesthetics and the overall life of the product. Selection of a UV stabilizer largely depends upon the surface to be protected, envisioned functional life & sensitivity to photodegradation. Several engineering thermoplastics like polyamides being majorly used for outdoor applications require long time U.V stabilization. For e.g.polybutylene terephthalate (PBT) finds uses in pigmented automotive exterior applications. Polyurethane based end products like automotive door trims, instrument panels, steering wheels, window sealants, head and arm rests and shoe soles, degrade when exposed to heat and light. Such degradation causes discoloration and formation of cracks. In this selection guide you will come across different UV Stabilizers that are added to impart typical functionalities to the plastic. For e.g. Hindered amine light stabilizers are derivatives of 2, 2, 6, 6-tetramethyl piperidine. They are extremely efficient stabilizers against light-induced degradation of most polymers. HALS do not absorb UV radiation, but act as antioxidants to inhibit or slow down the photochemical degradation of the polymer. Significant levels of UV stabilization are achieved at relatively low concentrations as during the stabilization process HALS get generated rather than being consumed. Others like benzotriazoles and benzophenones are cost effective and provide better performance than other types of UV stabilizers. Benzotriazoles are widely used in high temperature resins like acrylics and polycarbonates. While benzophenones find applications in polyolefins, PVC, etc. uv stabilizer are used individually or together to achieve the synergic effect. Click to check our UV stabilizers selection guide. Any further questions, chat with our online sales or mail at info@linchemical.com Linsorb UV Stabilizers Portfolio Related posts UV Stabilizer additives for polyolefins UV Stabilizer additives for special polymers UV Stabilizer additives for special coating UV Stabilizer additives for special adhesives If you are experiencing issues regarding your polymers or current additives, or sourcing additives or polymers additive solution? this maybe the ending of your sourcing. Chat with our online engineer, or file the form below. We’ll back to you in 12hous, guaranteed. UV Stabilizers To prevent degradation when exposed to heat, cold and uv-light, plastics require stabilization. Specially designed plastic UV Stabilizers protect the polymer during processing and ensure that plastic end products retain their physical properties during use, prolonging their life. SONGWON offers as a leading manufacturer of polymer UV Stabilizers a comprehensive range of processing, heat and uv-light UV Stabilizers as additives for plastics in a variety of blends and physical forms that facilitate handling and application. Information on the available physical forms is provided in the Technical Datasheets. Manufacturer of Polymer UV Stabilizers / UV Stabilizer Solutions for Plastics Antioxidants, Binary Blends & Thioesters SONGNOX® antioxidants prolong the life of plastics Phenolic antioxidants (AOs), also known as primary antioxidants, are highly effective, non-discoloring UV Stabilizers for organic substrates that are prone to oxidation, e.g., plastics, synthetic fibers, elastomers and waxes. They act as free radical scavengers, and are primarily used to protect the finished product. Phosphite antioxidants, also known as secondary antioxidants, act as peroxide decomposers, protecting the polymer and ensuring color retention of oxidation-prone organic polymers, especially during processing. Thioester antioxidants decompose and neutralize hydroperoxides formed through polymer oxidation. Thioesters are used to provide heat aging protection and to preserve color. Aminic antioxidants help to preserve physical and surface properties, including color, and scorch and heat resistance. Binary blends are a combination of a primary (phenolic) antioxidant and a secondary (phosphite) antioxidant for optimum stabilization during processing and service life. UV Stabilizer Solutions SONGXTEND® stabilization excellence & tailor-made solutions Our SONGXTEND® range of innovative stabilization packages solves a number of the key issues our customers face during processing, conversion and end-use life cycles. SONGXTEND® UV Stabilizer Solutions provide: processing stabilization solutions for PP high heat stabilization in PP based automotive applications solutions for PP fiber & thin wall injection molded grades Our highly advanced production processes and technology enable us to tailor our UV Stabilizer solution products to specification. Hindered Amine Light UV Stabilizers (HALS) SABO®STAB hindered amine light UV Stabilizers (HALS) neutralize harmful UV radiation Hindered amine light UV Stabilizers (HALS) protect polymers from degradation due to UV exposure by neutralizing them. HALS regenerate during neutralization and continue to provide protection throughout the life of the end product. They also act as primary antioxidants with low color generation. Monomeric HALS provide effective surface protection, while polymeric HALS protect the core of the material. SONGWON has a long-term global distribution agreement for distribution of SABO HALS light UV Stabilizers. UV Stabilizer Photo-oxidation is the result of the combined action of light and oxygen, with the action of sunlight in the presence of the air’s oxygen being the most important example. Photo-oxidation of polymers and other materials leads to degradation, discoloration and product failure unless it is prevented or significantly retarded. Mayzo supplies products from three general classes of UV stabilizers: UV Absorbers (which include benzotriazoles and benzophenones) HALS (hindered amine light UV stabilizers) UV Stabilizers – UV Absorber & Hindered Amine Light Stabilizers (HALS) UV stabilizer range contains two types of light stabilizers: Ultraviolet Light Absorbers (UVA) and Hindered-Amine Light Stabilizers (HALS), used individually or as blends. UVA filter harmful UV light and help prevent color change and delamination of coatings, adhesives, and sealants. HALS trap free radicals once they are formed and are effective in retaining surface properties such as gloss and prevent cracking and chalking of paints. The combination of these two families is highly synergistic. UV stabilizer product list UV Absorber BP-3, BP-6, P, 1130, 1164, 1157, 234, 326, 329, 360, 3638, 384-2,400, 531, 928, 99-2, 5050, 5060. Hindered Amine Light Stabilizers 119, 292, 622, 765, 770, 783, 791, 944, 2020, 3808PP5, 3853PP5 UV Stabilizers for Polymers, Plastics, Coatings, Rubber BASF, Songwon, Addivant and Baoxu Chemical UV Stabilizer Compare Baoxu chemical UV stabilizers are min99% similar according to IR, over half of our domestic customers use our UV stabilizers as replacement of imports to have a competitive edge. We control batch to batch quality consistency, to further protect our buyers interests. We use Paypal, Escrow which now known as Alibaba Secure Payment for samples express fees (samples are free to offer). UV stabilizer General name of additives used to prevent degradation of organic coating films exposed to UV light. UV stabilizers are classified into two groups. UV stabilizers (also called as UV absorbers). They convert the absorbed UV energy into heat and this heat is then dissipated through the substrate. Benzophenones and benzotriazole derivatives are commonly used UV stabilizers. The other group is free radical scavengers. They act by trapping the free radicals formed by UV light and decompose these radicals along with themselves hereby suppress the degradation of coating. Hindered amine light stabilizers (HALS) are used as free radical scavengers. UV Stabilizers for Engineering PlasticsEngineering plastics like polyamides, polyesters, polycarbonates are majorly used for applications that demand long time U.V stabilization. This selection guide mainly deals with the query "which UV Stabilizer is ideal for which plastic"? This guide will familiarize you with various UV stabilizers used with these engineering plastics. You would be able to find out the functionalities of different UV stabilizers for different engineering plastics in demand. Also one can find the starting point formulations of polycarbonates, polyacetal polyoxymethylene, polyesters like PET & PBT and polyamides.By Pascal Xanthopoulos UV StabilizersUV Stabilizers for PolycarbonateUV Stabilizers for POMUV Stabilizers for PolyestersUV Stabilizers for Polyamides UV Stabilizers UV stabilizers combat the degradation that plastics can undergo under the effects of sunlight, UV rays, heat and reaction with oxygen. The changes witnessed in a plastic can range from discoloration to formation of cracks. Incorporating a UV stabilizer into the polymer mix, improves the appearance/aesthetics and the overall life of the product. Selection of a UV stabilizer largely depends upon the surface to be protected, envisioned functional life & sensitivity to photodegradation. Several engineering thermoplastics like polyamides being majorly used for outdoor applications require long time U.V stabilization. For e.g.polybutylene terephthalate (PBT) finds uses in pigmented automotive exterior applications. Polyurethane based end products like automotive door trims, instrument panels, steering wheels, window sealants, head and arm rests and shoe soles, degrade when exposed to heat and light. Such degradation causes discoloration and formation of cracks. In this selection guide you will come across different UV Stabilizers that are added to impart typical functionalities to the plastic. For e.g. Hindered amine light stabilizers are derivatives of 2, 2, 6, 6-tetramethyl piperidine. They are extremely efficient stabilizers against light-induced degradation of most polymers. HALS do not absorb UV radiation, but act as antioxidants to inhibit or slow down the photochemical degradation of the polymer. Significant levels of UV stabilization are achieved at relatively low concentrations as during the stabilization process HALS get generated rather than being consumed. Others like benzotriazoles and benzophenones are cost effective and provide better performance than other types of UV stabilizers. Benzotriazoles are widely used in high temperature resins like acrylics and polycarbonates. While benzophenones find applications in polyolefins, PVC, etc. uv stabilizer are used individually or together to achieve the synergic effect. Click to check our UV stabilizers selection guide. Any further questions, chat with our online sales or mail at info@linchemical.com Linsorb UV Stabilizers Portfolio Related posts UV Stabilizer additives for polyolefins UV Stabilizer additives for special polymers UV Stabilizer additives for special coating UV Stabilizer additives for special adhesives If you are experiencing issues regarding your polymers or current additives, or sourcing additives or polymers additive solution? this maybe the ending of your sourcing. Chat with our online engineer, or file the form below. We’ll back to you in 12hous, guaranteed. UV Stabilizers To prevent degradation when exposed to heat, cold and uv-light, plastics require stabilization. Specially designed plastic UV Stabilizers protect the polymer during processing and ensure that plastic end products retain their physical properties during use, prolonging their life. SONGWON offers as a leading manufacturer of polymer UV Stabilizers a comprehensive range of processing, heat and uv-light UV Stabilizers as additives for plastics in a variety of blends and physical forms that facilitate handling and application. Information on the available physical forms is provided in the Technical Datasheets. Manufacturer of Polymer UV Stabilizers / UV Stabilizer Solutions for Plastics Antioxidants, Binary Blends & Thioesters SONGNOX® antioxidants prolong the life of plastics Phenolic antioxidants (AOs), also known as primary antioxidants, are highly effective, non-discoloring UV Stabilizers for organic substrates that are prone to oxidation, e.g., plastics, synthetic fibers, elastomers and waxes. They act as free radical scavengers, and are primarily used to protect the finished product. Phosphite antioxidants, also known as secondary antioxidants, act as peroxide decomposers, protecting the polymer and ensuring color retention of oxidation-prone organic polymers, especially during processing. Thioester antioxidants decompose and neutralize hydroperoxides formed through polymer oxidation. Thioesters are used to provide heat aging protection and to preserve color. Aminic antioxidants help to preserve physical and surface properties, including color, and scorch and heat resistance. Binary blends are a combination of a primary (phenolic) antioxidant and a secondary (phosphite) antioxidant for optimum stabilization during processing and service life. UV Stabilizer Solutions SONGXTEND® stabilization excellence & tailor-made solutions Our SONGXTEND® range of innovative stabilization packages solves a number of the key issues our customers face during processing, conversion and end-use life cycles. SONGXTEND® UV Stabilizer Solutions provide: processing stabilization solutions for PP high heat stabilization in PP based automotive applications solutions for PP fiber & thin wall injection molded grades Our highly advanced production processes and technology enable us to tailor our UV Stabilizer solution products to specification. Hindered Amine Light UV Stabilizers (HALS) SABO®STAB hindered amine light UV Stabilizers (HALS) neutralize harmful UV radiation Hindered amine light UV Stabilizers (HALS) protect polymers from degradation due to UV exposure by neutralizing them. HALS regenerate during neutralization and continue to provide protection throughout the life of the end product. They also act as primary antioxidants with low color generation. Monomeric HALS provide effective surface protection, while polymeric HALS protect the core of the material. SONGWON has a long-term global distribution agreement for distribution of SABO HALS light UV Stabilizers. UV Stabilizer Photo-oxidation is the result of the combined action of light and oxygen, with the action of sunlight in the presence of the air’s oxygen being the most important example. Photo-oxidation of polymers and other materials leads to degradation, discoloration and product failure unless it is prevented or significantly retarded. Mayzo supplies products from three general classes of UV stabilizers: UV Absorbers (which include benzotriazoles and benzophenones) HALS (hindered amine light UV stabilizers) UV Stabilizers – UV Absorber & Hindered Amine Light Stabilizers (HALS) UV stabilizer range contains two types of light stabilizers: Ultraviolet Light Absorbers (UVA) and Hindered-Amine Light Stabilizers (HALS), used individually or as blends. UVA filter harmful UV light and help prevent color change and delamination of coatings, adhesives, and sealants. HALS trap free radicals once they are formed and are effective in retaining surface properties such as gloss and prevent cracking and chalking of paints. The combination of these two families is highly synergistic. UV stabilizer product list UV Absorber BP-3, BP-6, P, 1130, 1164, 1157, 234, 326, 329, 360, 3638, 384-2,400, 531, 928, 99-2, 5050, 5060. Hindered Amine Light Stabilizers 119, 292, 622, 765, 770, 783, 791, 944, 2020, 3808PP5, 3853PP5 UV Stabilizers for Polymers, Plastics, Coatings, Rubber BASF, Songwon, Addivant and Baoxu Chemical UV Stabilizer Compare Baoxu chemical UV stabilizers are min99% similar according to IR, over half of our domestic customers use our UV stabilizers as replacement of imports to have a competitive edge. We control batch to batch quality consistency, to further protect our buyers interests. We use Paypal, Escrow which now known as Alibaba Secure Payment for samples express fees (samples are free to offer).
UVINUL A PLUS B

Uvinul A plus B refers to a combination of two chemical compounds used in sunscreens and other personal care products to provide UV protection.
The two components are "Uvinul A Plus" and "Uvinul B."
These compounds are organic UV filters that absorb or block certain wavelengths of ultraviolet (UV) radiation from the sun, helping to protect the skin from sunburn and potential damage caused by UV exposure.
Uvinul A plus B is a synergistic combination of UV filters offering comprehensive protection against UVA and UVB rays.



APPLICATIONS


Uvinul A plus B finds its primary application in sunscreens, where it serves as a crucial component for providing effective UV protection.
This combination of UV filters is formulated into a range of sun protection products, including lotions, creams, sprays, and sticks.

Uvinul A plus B is widely used in daily skincare routines as a preventive measure against the harmful effects of sun exposure.
Uvinul A plus B is essential in beach and sport sunscreens, catering to individuals engaged in outdoor activities.
Its inclusion in facial moisturizers with SPF enhances daily protection against photoaging caused by UV rays.

Uvinul A plus B is commonly used in makeup products, offering sun protection without compromising cosmetic elegance.
Uvinul A plus B is also utilized in lip balms with SPF, ensuring UV protection for the delicate skin of the lips.
Uvinul A plus B is a key component in body lotions and creams formulated to provide all-over sun protection during daily application.
Skincare brands often incorporate Uvinul A plus B into products aimed at maintaining the skin's health and appearance.
Its application extends to specialty sunscreens, such as those designed for sensitive skin or specific outdoor activities.
Uvinul A plus B is suitable for year-round use, as UV exposure can occur even on cloudy days or during winter months.

Uvinul A plus B is often found in children's sunscreens, offering parents peace of mind when protecting their children's delicate skin.
Uvinul A plus B is used in anti-aging skincare lines to counteract the premature aging effects of UV radiation.
Uvinul A plus B's compatibility with various formulations makes it a versatile choice for different sunscreen product types.

Uvinul A plus B contributes to the formulation of sunscreens with various SPF levels, allowing users to choose the appropriate protection.
Uvinul A plus B is vital for preventing sunburn, reducing the risk of skin cancer, and maintaining healthy skin.
Uvinul A plus B's broad-spectrum coverage addresses both short-term effects like sunburn and long-term photoaging concerns.
Uvinul A plus B is an integral ingredient in sun protection products that aim to meet regulatory and safety standards.

Brands often highlight the presence of Uvinul A plus B on product labels to emphasize their commitment to UV protection.
Uvinul A plus B is chosen for its ability to provide stable and effective UV protection in various environmental conditions.
Uvinul A plus B's popularity lies in its ability to deliver sun protection without leaving a heavy or greasy residue.
Uvinul A plus B is utilized in skincare products that cater to individuals seeking multifunctional benefits, including hydration and protection.
Uvinul A plus B enables consumers to incorporate sun protection seamlessly into their skincare routines.

Its use is not limited to specific skin types, making it accessible and beneficial for a wide range of users.
Whether for daily wear, outdoor activities, or specific skin concerns, Uvinul A plus B remains a trusted choice for reliable sun protection.

Uvinul A plus B serves as a fundamental component in sunscreens intended for use on both the face and body.
Uvinul A plus B is integrated into tinted sunscreens, providing both sun protection and light coverage.

Brands often incorporate Uvinul A plus B into after-sun products, offering soothing care for skin exposed to UV radiation.
Its inclusion in facial serums with SPF combines skincare benefits with essential sun protection.
Uvinul A plus B is frequently found in makeup primers, acting as a base that shields the skin from UV damage.

Uvinul A plus B is used in daily moisturizers with SPF, making sun protection an integral part of everyday skincare routines.
Uvinul A plus B is essential in body sunscreens designed for outdoor enthusiasts and those spending extended time in the sun.
Uvinul A plus B is featured in sun protection products tailored to specific skin concerns, such as oil control or hydration.

Uvinul A plus B plays a role in setting sprays with SPF, allowing users to refresh their sun protection throughout the day.
Uvinul A plus B's application extends to skincare products formulated to counteract the effects of photoaging.
Uvinul A plus B is an essential ingredient in skincare products designed to minimize the appearance of hyperpigmentation caused by sun exposure.

Brands often integrate Uvinul A plus B into facial mists with SPF, offering on-the-go sun protection and refreshment.
Uvinul A plus B is featured in cosmetic products that prioritize both aesthetics and skin health.

Uvinul A plus B enables the formulation of sunscreens suitable for individuals with different skin tones and types.
Uvinul A plus B contributes to the creation of sun protection products for sensitive skin, offering gentle care without causing irritation.
Uvinul A plus B is a key component in skincare lines that focus on maintaining youthful and healthy-looking skin.
Brands highlight the presence of Uvinul A plus B in products intended for outdoor activities like hiking, sports, and beach outings.
Uvinul A plus B supports the formulation of lightweight and breathable sunscreens, promoting user comfort during wear.
Uvinul A plus B is integral to sun protection products designed to be worn under makeup without compromising its finish.
Uvinul A plus B's application in lip products with SPF ensures UV protection for the often overlooked skin of the lips.

Uvinul A plus B is used in skincare products aiming to address the negative effects of environmental factors, including UV radiation.
Brands emphasize Uvinul A plus B in products that align with the evolving consumer preference for skincare with added benefits.
Its integration in beauty products underscores the commitment to holistic skin health, encompassing both appearance and protection.
Uvinul A plus B supports the creation of sun protection products that cater to the preferences of individuals seeking specific textures and application methods.
Its use in a wide array of sun protection and skincare products demonstrates its role as a foundational ingredient in promoting skin well-being.

Uvinul A plus B is found in sunscreens formulated for various skin types, ensuring accessible sun protection for everyone.
Uvinul A plus B is a key ingredient in sunscreens for individuals with active lifestyles, offering dependable protection during workouts and outdoor activities.
Uvinul A plus B's use in lightweight sunscreen formulations addresses the demand for products that feel comfortable on the skin.

Uvinul A plus B supports the creation of sunscreens suitable for daily urban life, guarding against UV radiation in city environments.
Its application in foundation products with SPF underscores the integration of sun protection into everyday makeup routines.
Brands often integrate Uvinul A plus B into sunscreens that cater to specific climates, adapting to varying UV levels.
Uvinul A plus B is a vital component in sunscreens recommended by dermatologists to prevent the exacerbation of skin conditions triggered by UV exposure.

Uvinul A plus B contributes to the formulation of sunscreens suitable for those with outdoor professions or hobbies.
Uvinul A plus B is chosen for its ability to provide UV protection without leaving a white cast on the skin.
Its inclusion in primer products with SPF primes the skin for makeup while creating a barrier against UV rays.
Uvinul A plus B is used in sunscreens that prioritize the balance between protection and allowing the skin to breathe.
Uvinul A plus B supports the development of sun protection products tailored to specific age groups, including children, adults, and seniors.

Uvinul A plus B's integration in facial mists with SPF offers a refreshing and convenient way to reapply sun protection throughout the day.
Uvinul A plus B is included in skincare products formulated to address the concerns of individuals with sensitive or reactive skin.
Uvinul A plus B is an essential ingredient in sunscreens with a transparent finish, suitable for individuals with various skin tones.
Uvinul A plus B's application in BB creams with SPF combines makeup coverage with essential sun protection.
Uvinul A plus B contributes to the creation of sunscreens recommended for individuals undergoing specific skincare treatments that increase sun sensitivity.

Brands highlight Uvinul A plus B in products that align with the trend of customizable skincare routines, where protection is tailored to individual needs.
Its presence in sun protection products reinforces a holistic approach to skincare that encompasses prevention and preservation.
Uvinul A plus B is a building block in sunscreens designed for the delicate eye area, protecting against UV-induced fine lines and wrinkles.
Uvinul A plus B supports the formulation of sunscreens with antioxidant-rich ingredients, amplifying their protective benefits.
Uvinul A plus B is used in products that cater to those seeking sun protection that complements their minimalist skincare philosophy.

Brands emphasize Uvinul A plus B in sunscreens promoted as travel essentials, essential for maintaining skin health during trips.
Uvinul A plus B's integration in facial sunscreen products with skin-enhancing ingredients supports a comprehensive skincare approach.
Uvinul A plus B serves as a cornerstone of sun protection, driving innovation in skincare products that prioritize both health and beauty.



DESCRIPTION


Uvinul A plus B refers to a combination of two chemical compounds used in sunscreens and other personal care products to provide UV protection.
The two components are "Uvinul A Plus" and "Uvinul B."
These compounds are organic UV filters that absorb or block certain wavelengths of ultraviolet (UV) radiation from the sun, helping to protect the skin from sunburn and potential damage caused by UV exposure.
Uvinul A plus B is a synergistic combination of UV filters offering comprehensive protection against UVA and UVB rays.

Uvinul A plus B harnesses diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus) and ethylhexyl triazone (Uvinul B) for optimal defense.
Its effectiveness lies in its ability to absorb and block UVA and UVB rays, shielding the skin from their damaging effects.

Uvinul A plus B provides advanced sun protection suitable for various outdoor activities and extended sun exposure.
The photo-stable nature of its components ensures its reliability even during prolonged periods under the sun.
Uvinul A plus B is designed with skin compatibility in mind, minimizing the risk of irritation often associated with UV filters.
Upon application, products containing Uvinul A plus B offer a transparent and non-greasy finish for a comfortable experience.
The broad-spectrum coverage of this combination guards against sunburn, skin aging, and potential damage.

Uvinul A plus B forms a protective barrier on the skin, acting as a shield against the harmful effects of UV radiation.
Dermatologists often recommend sunscreens with Uvinul A plus B due to its reliable protection and compatibility.
By incorporating Uvinul A plus B into daily skincare routines, individuals can minimize the effects of sun exposure on their skin.
Uvinul A plus B is suitable for outdoor enthusiasts, providing reliable protection during activities such as swimming and hiking.
The combination's effectiveness aligns with efforts to promote sun safety and minimize the risks of UV-induced damage.

Uvinul A plus B aids in reducing the appearance of fine lines and wrinkles, contributing to a more youthful appearance.
The fusion of diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus) and ethylhexyl triazone (Uvinul B) marks a skincare milestone.
Confidence in outdoor activities is enhanced by the knowledge that Uvinul A plus B is safeguarding the skin from UV harm.
Scientifically tested and formulated, Uvinul A plus B reflects the skincare industry's commitment to effective sun protection.
Its international standards ensure individuals worldwide can access reliable sun protection.

Uvinul A plus B's formulation is based on rigorous research and testing, reinforcing its role in skincare routines.
Incorporating Uvinul A plus B into daily life contributes to long-term skin health and youthful vibrancy.

Uvinul A plus B defends against UV-induced aging, maintaining the skin's vitality and appearance.
Its dual filters revolutionize skincare by offering both UVA and UVB protection in a single solution.
Whether for hiking, swimming, or everyday activities, Uvinul A plus B is a trusted shield against UV exposure.

Daily application provides a shield against sun-induced skin damage, offering both confidence and comfort.
With Uvinul A Plus B, skin protection becomes an investment in overall well-being and lasting skin health.



FIRST AID


Inhalation:

If Uvinul A plus B is inhaled and respiratory irritation occurs, move the affected person to fresh air immediately.
If breathing difficulties persist, seek medical attention.


Skin Contact:

In case of skin contact, remove contaminated clothing and rinse the affected area thoroughly with plenty of water.
If irritation or redness develops, seek medical advice.
Wash contaminated clothing before reuse.


Eye Contact:

In case of eye contact, rinse the affected eye gently with water for at least 15 minutes, while keeping the eyelid open.
Seek medical attention if irritation, redness, or discomfort persists.


Ingestion:

If Uvinul A plus B is ingested accidentally, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth with water if the person is conscious and seek medical attention.



HANDLING AND STORAGE


Handling:

Avoid Direct Contact:
When handling "Uvinul A Plus B," avoid direct skin and eye contact to prevent potential irritation.

Personal Protective Equipment:
Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and lab coats when handling the product.

Ventilation:
Use in a well-ventilated area to minimize inhalation exposure.
If working in an enclosed space, consider using local exhaust ventilation.

Avoid Inhalation:
Avoid inhaling dust, vapors, or mists generated during handling.
If dust is generated, wear a mask designed to filter particulates.

Prevent Ingestion:
Do not eat, drink, or smoke while handling Uvinul A Plus B.
Wash hands thoroughly after handling and before eating or touching the face.

Spill Response:
In case of spills, carefully sweep or vacuum up the material, taking precautions to minimize the generation of dust.
Dispose of waste according to regulations.


Storage:

Cool, Dry Place:
Store Uvinul A plus B in a cool, dry place away from direct sunlight, heat sources, and open flames.

Temperature Control:
Maintain storage temperatures within the range specified on the product's safety data sheet (SDS) to ensure stability and performance.

Original Containers:
Keep the product in its original container, tightly closed, and properly labeled.

Compatibility:
Store Uvinul A plus B away from incompatible materials, including strong oxidizers, reducing agents, and reactive chemicals.

Segregation:
Separate Uvinul A plus B from food, beverages, and animal feed to prevent cross-contamination.

Moisture Control:
Protect the product from moisture to avoid degradation and clumping.

Childproofing:
Store in a location inaccessible to children and unauthorized personnel.



SYNONYMS


UV Protection Blend
Sunscreen Ingredient Combination
Broad-Spectrum UV Filters
Sun Protection Complex
UV Defense Mixture
Sunblock Formulation
Photoprotective Blend
Sunscreen Component Mix
Solar Radiation Shield
UV Absorption Combination
Radiation Barrier Formula
Sunscreen Additive Mix
Solar Defense Blend
UV Ray Blocking Compound
Photoprotection Matrix
Sunscreen Agent Fusion
Sunblock Ingredient Blend
Solar Radiation Screen
UV-Absorbing Compound Pair
UV Ray Filter Blend
Sunscreen Actives Mixture
Radiation Absorption Duo
Sun Guarding Mixture
Photoprotectant Combination
Sunscreen Defense Cocktail
Solar Shield Formula
Sunscreen Active Duo
Radiation Absorption Blend
UV Defense Cocktail
Photoprotection Pairing
Sunscreen Component Fusion
Sunblock Filter Mixture
VALERIC ACID
VANILLIC ACID N° CAS : 121-34-6 "Bien" dans toutes les catégories. Nom INCI : VANILLIC ACID Nom chimique : Benzoic acid, 4-hydroxy-3-methoxy- N° EINECS/ELINCS : 204-466-8 Ses fonctions (INCI) Non classé : Non classé
VALERIC ACID
VALERIC ACID = PENTANOIC ACID = n-VALERIC ACID


CAS Number: 109-52-4
EC Number: 203-677-2
MDL number: MFCD00004413
Molecular Formula: C5H10O2 or CH3(CH2)3COOH


Valeric acid (pentanoic acid, C5H10O2) is a straight, saturated chain, alkyl carboxylic acid.
Valeric acid or pentanoic acid is a straight-chain alkyl carboxylic acid with the chemical formula CH3(CH2)3COOH.
Like other low-molecular-weight carboxylic acids, Valeric acid has an unpleasant odor.
Valeric acid is found in the perennial flowering plant Valeriana officinalis, from which it gets its name.
Valeric acid's primary use is in the synthesis of its esters.


Salts and esters of valeric acid are known as valerates or pentanoates.
Valeric acid is a straight-chain saturated fatty acid containing five carbon atoms.
Valeric acid has a role as a plant metabolite.
Valeric acid is a short-chain fatty acid and a straight-chain saturated fatty acid.
Valeric acid is a conjugate acid of a valerate.


Valeric acid is a natural product found in Rhododendron mucronulatum, Hansenia forbesii, and other organisms with data available.
Valeric acid appears as a colorless liquid with a penetrating unpleasant odor.
Valeric acid's Density is 0.94 g / cm3.
Valeric acid's freezing point is -93.2 °F (-34 °C).
Valeric acid's boiling point is 365.7 °F (185.4 °C).


Valeric acid's flash point is 192 °F (88.9 °C).
Valeric acid (pentanoic acid, C5H10O2) is a straight, saturated chain, alkyl carboxylic acid.
Valeric acid is a colorless, oily liquid with a very unpleasant odor of stale cheese.
Valeric acid exists in four isomeric forms, one of which contains an asymmetric carbon atom and consequently occurs in two optically active modifications and one optically inactive modification.


Valeric acid is found naturally as free or as esters in the vegetable and animal kingdoms.
Valeric acid belongs to the class of organic compounds known as straight chain fatty acids.
These are fatty acids with a straight aliphatic chain.
Valeric acid is a straight-chain alkyl carboxylic acid and saturated fatty acid with the chemical formula CH3(CH2)3COOH.
Valeric acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.


Valeric acid is a colorless, oily liquid with an unpleasant odor.
Valeric acid can be extracted by boiling water or soda from the roots of Angelica archangelica and Valeriana officinalis (from which valeric acid gets the name).
The acid can also be obtained by oxidizing fermentation amyl alcohol with chromic acid.
The acid can be formed by microorganisms during the anaerobic fermentation of CO2 and H2 (discussed above) and by the fermentation of other carbon sources, such as wastewater solids.


Valeric acid is a straight-chain saturated fatty acid containing five carbon atoms.
Valeric acid, or pentanoic acid, is a straight chain alkyl carboxylic acid with the chemical formula CH3(CH2)3COOH.
Like other low molecular weight carboxylic acids, it has a very unpleasant odor.
Valeric acid is commonly found in human feces, with an average concentration of 2.4 umol/g feces (range of 0.6-3.8 umol/g) (PMID:6740214 ).
Valeric acid is produced by the gut microbiota, typically Clostridia species and other gut bacterial species such as Megasphaera massiliensis MRx0029 (PMID:30052654 ) via the condensation of ethanol with propionic acid (PMID:18116989 ).


Valeric acid is largely considered as a gut microbial metabolite.
Recently, valeric acid has been found to exert strong gut protective effects.
Valeric acid is also found in certain plants, specifically in the perennial flowering plant valerian (Valeriana officinalis), from which it gets its name.
Valeric acid is considered safe as a food additive by the World Health Organization.
Valeric acid is also known as pentanoic acid.


Valeric acid is a straight-chain alkyl carboxylic acid.
Valeric acid 's chemical formula is C5H10O2.
Valeric acid has a very unpleasant odor like the carboxylic acids with low molecular weight.
Valeric acid can be found in the perennial flowering plant valerian naturally, which is also known as valeriana officinalis.
The most important function of valeric acid is in the synthesis of its esters.


Volatile esters synthesized from valeric acid have more pleasant odors compared with valeric acid.
Valeric acid has similar chemical structure with gamma-Hydroxybutyric acid, which is a naturally occurring neurotransmitter and a psychoactive drug.
Valeric acid also has similar structure with neurotransmitter gamma-Aminobutyric acid, which is the chief inhibitory neurotransmitter in the mammalian central nervous system.
Valeric acid lacks the alcohol and amine functional groups, which contribute to the biological activities of GHB and GABA.


Valeric acid is methylated and results in the formation of mevalonic acid.
Valeric acid, also known as pentanoic acid or valerate, belongs to the class of organic compounds known as straight chain fatty acids.
These are fatty acids with a straight aliphatic chain.
Valeric acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.


Valeric acid, or pentanoic acid, is a straight-chain alkyl carboxylic acid with the chemical formula C5H10O2.
Like other low-molecular-weight carboxylic acids, it has a very unpleasant odor.
Valeric acid is found naturally in the perennial flowering plant valerian (Valeriana officinalis), from which it gets its name.
Valeric acid 's primary use is in the synthesis of its esters.


Valeric acid has a similar structure to both GHB and the neurotransmitter GABA.
Valeric acid differs from valproic acid simply by lacking a 3-carbon side chain.
Valeric acid is an inert ingredient in controlling pest.
Valeric acid is an organic chemical compound with the chemical formula C5H10O2.
The primal use of Valeric acid is in the syntesis of ester.



USES and APPLICATIONS of VALERIC ACID:
Valeric acid is used Stabilizers, Plasticizers, Coatings additives, Lubricants, Pharmaceuticals, Pesticides, Perfumes, Food additives, Chemical intermediates, and perfuming agents.
Several, including ethyl valerate and pentyl valerate are used as food additives because of their fruity flavors.
Valeric acid occurs naturally in some foods but is also used as a food additive.


Valeric acid is used for the preparation of derivatives, notably its volatile esters which, unlike the parent acid, have pleasant odors and fruity flavors and hence find applications in perfumes, cosmetics and foodstuffs.
Typical examples are the methyl valerates, ethyl valerates, and pentyl valerates.
Valeric acid, and its esters, is mainly used in perfumes and cosmetics, as food additives because of the fruity flavor of the esters, and as plasticizers and pharmaceuticals.


Industrially valeric acid is primarily used in the synthesis of its esters.
Volatile esters of valeric acid tend to have pleasant odors and are used in perfumes and cosmetics.
Ethyl valerate and pentyl valerate are used as food additives because of their fruity flavours.
Hydrolysis of these valerate-containing food additives in the gut can also lead to the appearance of valerate in blood, urine and stool samples.
Valeric acid is predominantly used in the synthesis of esters.


Valeric Acid is a reagent that is used in the biological studies of (D)-b-hydroxybutyrate which inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.
Valeric acid is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Valeric acid is used in the following products: perfumes and fragrances and cosmetics and personal care products.


Other release to the environment of Valeric acid is likely to occur from: indoor use as processing aid.
Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals.
Valeric acid is also used as a flavoring aid in foods.
Valeric acid is can be used in perfumes and cosmetics.


Volatile esters of valeric acid tend to have pleasant odors and are used in perfumes and cosmetics.
Ethyl valerate and pentyl valerate are used as food additives because of their fruity flavors.
Valeric acid, is used as a sex attractant of the sugar beet wireworm, Limonius californicus.
Valeric acid is used predominantly as an intermediate in the manufacture of flavors and perfumes, ester type lubricants, plasticizers and vinyl stabilizers.


Valeric acid is a food additive used as a synthetic flavoring substance dan adjuvant.
Valeric acid tends to have pleasant odors and are used in perfumes and cosmetics.
Some of these esters are used as food additives because of their fruity flavors.
Volatile esters of valeric acid tend to have pleasant odors and are used in perfumes and cosmetics.



HISTORY of VALERIC ACID:
Valeric acid is a minor constituent of the perennial flowering plant valerian (Valeriana officinalis), from which it gets its name.
The dried root of this plant has been used medicinally since antiquity.
The related isovaleric acid shares its unpleasant odor and their chemical identity was investigated by oxidation of the components of fusel alcohol, which includes the five-carbon amyl alcohols.
Valeric acid is one volatile component in swine manure.
Other components include other carboxylic acids, skatole, trimethyl amine, and isovaleric acid.
Valeric acid is also a flavor component in some foods.



MANUFACTURE of VALERIC ACID:
In industry, valeric acid is produced by the oxo process from 1-butene and syngas, forming valeraldehyde, which is oxidised to the final product.
H2 + CO + CH3CH2CH=CH2 → CH3CH2CH2CH2CHO → valeric acid
Valeric acid can also be produced from biomass-derived sugars via levulinic acid and this alternative has received considerable attention as a way to produce biofuels.



REACTIONS of VALERIC ACID:
Valeric acid reacts as a typical carboxylic acid: it can form amide, ester, anhydride, and chloride derivatives.
The latter, valeryl chloride is commonly used as the intermediate to obtain the others.


BENEFITS of VALERIC ACID:
*Low molecular weight
*World's largest portfolio of solvents



ALTERNATIVE PARENTS of VALERIC ACID:
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS of VALERIC ACID:
*Straight chain fatty acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



BIOLOGY:
In humans, valeric acid is a minor product of the gut microbiome and can also be produced by metabolism of its esters found in food.
The restoration of levels of this acid in the gut has been suggested as the mechanism that results in control of Clostridioides difficile infection after fecal microbiota transplant.



VALERATE SALTS AND ESTERS:
The valerate, or pentanoate, ion is C4H9COO−, the conjugate base of valeric acid.
Valeric acid is the form found in biological systems at physiological pH.
A valerate, or pentanoate, compound is a carboxylate salt or ester of valeric acid.
Many steroid-based pharmaceuticals, for example ones based on betamethasone or hydrocortisone, include the steroid as the valerate ester.



PHYSICAL and CHEMICAL PROPERTIES of VALERIC ACID:
Chemical formula: C5H10O2
Molar mass: 102.133 g·mol−1
Appearance: Colorless liquid
Density: 0.930 g/cm3
Melting point: −34.5 °C (−30.1 °F; 238.7 K)
Boiling point: 185 °C (365 °F; 458 K)
Solubility in water: 4.97 g/100 mL
Acidity (pKa): 4.82
Magnetic susceptibility (χ): -66.85·10−6 cm3/mol
Molecular Weight: 102.13
XLogP3: 1.4
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 3


Exact Mass: 102.068079557
Monoisotopic Mass: 102.068079557
Topological Polar Surface Area: 37.3 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 59.1
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes


Physical state: clear, liquid
Color: colorless
Odor: Stench.
Melting point/freezing point:
Melting point/range: -20 - -18 °C - lit.
Initial boiling point and boiling range: 110 - 111 °C at 13 hPa - lit. 185 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 7,6 %(V)
Lower explosion limit: 1,6 %(V)
Flash point: 89 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 2,7 at 40 g/l at 20 °C


Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 2,3 mPa.s at 20 °C
Water solubility: ca.40 g/l at 20 °C - soluble
Partition coefficient: n-octanol/water:
log Pow: 1,8 at 25 °C
Vapor pressure: 0,19 hPa at 20 °C
Density: 0,939 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 51,6 mN/m at 1g/l at 20 °C
Dissociation constant: 4,8 at 22,5 °C
Relative vapor density: 3,53 - (Air = 1.0)


Appearance: colorless to pale yellow clear liquid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 0.93900 to 0.94200 @ 20.00 °C.
Pounds per Gallon - (est).: 7.823 to 7.848
Refractive Index: 1.40700 to 1.41100 @ 20.00 °C.
Melting Point: -35.00 to -34.00 °C. @ 760.00 mm Hg
Boiling Point: 184.00 to 186.00 °C. @ 760.00 mm Hg
Boiling Point: 112.00 to 113.00 °C. @ 50.00 mm Hg
Vapor Pressure: 0.452000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.5 ( Air = 1 )
Flash Point: 192.00 °F. TCC ( 88.89 °C. )
logP (o/w): 1.390
Soluble in: alcohol, ether, water, 1.86e+004 mg/L @ 25 °C (est)
Insoluble in: water


Molecular Formula / Molecular Weight: C5H10O2 = 102.13
Physical State (20 deg.C): Liquid
CAS RN: 109-52-4
Reaxys Registry Number: 969454
PubChem Substance ID: 87577803
SDBS (AIST Spectral DB): 3381
Merck Index (14): 9904
Appearance (Clarity): Clear
Appearance (Colour): Colourless
Appearance (Form): Liquid
Assay (GC): min. 99%
Density (g/ml) @ 20°C: 0.937-0.939
Refractive Index (20°C): 1.407-1.408
Boiling Range: 184-186°C



FIRST AID MEASURES of VALERIC ACID:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of VALERIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.



FIRE FIGHTING MEASURES of VALERIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of VALERIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,3 mm
Break through time: 480 min
Splash contact:
Material: Nature latex/chloroprene
Minimum layer thickness: 0,6 mm
Break through time: 30 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of VALERIC ACID:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.



STABILITY and REACTIVITY of VALERIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Valeric acid
PENTANOIC ACID
n-Valeric acid
109-52-4
n-Pentanoic acid
Valerianic acid
1-Butanecarboxylic acid
Propylacetic acid
Butanecarboxylic acid
pentoic acid
Kyselina valerova
VALERIC ACID, N-
Valeric acid, normal
n-Pentanoate
Valerate
FEMA No. 3101
Valeriansaeure
n-Valerate
1-pentanoic acid
NSC 406833
n-C4H9COOH
GZK92PJM7B
CH3-[CH2]3-COOH
CHEBI:17418
NSC-406833
64118-37-2
NCGC00183281-01
C5:0
DSSTox_CID_1655
DSSTox_RID_76267
DSSTox_GSID_21655
VALERICACID
CAS-109-52-4
SHF
HSDB 5390
Butane-1-carboxylic acid
EINECS 203-677-2
UNII-GZK92PJM7B
MFCD00004413
BRN 0969454
pentoate
Propylacetate
Valerianate
Valeriansaure
AI3-08657
Butanecarboxylate
1-pentanoate
1ylv
1-Butanecarboxylate
Valeric acid normal
n-BuCOOH
1173023-05-6
Valeric acid, 99%
Valeric acid, >=99%
bmse000345
EC 203-677-2
Pentanoic acid
Valeric acid
SCHEMBL5886
WLN: QV4
4-02-00-00868
MLS001066335
PENTANOIC ACID
VALERIC ACID
Pentanoic Acid (Valeric Acid)
CHEMBL268736
GTPL1061
DTXSID7021655
Valeric acid ( Pentanoic acid )
Valeric acid, analytical standard
HMS2267A03
Valeric acid-[3,4,5-13C3]
HY-N6056
Tox21_113414
Tox21_201561
Tox21_303030
LMFA01010005
NSC406833
STL169350
Valeric acid, >=99%, FCC, FG
ZINC31500905
AKOS000118960
DB02406
NCGC00183281-02
NCGC00183281-03
NCGC00256597-01
NCGC00259110-01
BS-42203
SMR000471834
CS-0032261
FT-0651620
FT-0694066
V0003
Valeric acid, pharmaceutical impurity standard
C00803
Q407796
J-002298
F2191-0105
Z955123768
1-Butanecarboxylic acid
CH3-[CH2]3-COOH
N-BuCOOH
N-Pentanoate
N-Pentanoic acid
N-Valeric acid
Pentanoate
Pentanoic acid
Pentoic acid
Propylacetic acid
Valerate
Valerianic acid
Valeriansaeure
Valeric acid, normal
1-Butanecarboxylate
N-Valerate
Pentoate
Propylacetate
Valerianate
Valerate, normal
1-Pentanoate
1-Pentanoic acid
Butanecarboxylate
Butanecarboxylic acid
Kyselina valerova
N-C4H9COOH
Valeriansaure
Valeric acid normal
N-Pentanoic acid, ammonium salt
N-Pentanoic acid, potassium salt
N-Pentanoic acid, sodium salt
N-Pentanoic acid, zinc salt
N-Pentanoic acid, maganese (+2) salt
N-Pentanoic acid, 11C-labeled
Lithium pentanoate
N-Pentanoic acid, 11C-labeled sodium salt
Valeric acid
1-Butanecarboxylate
1-Butanecarboxylic acid
1-pentanoate
1-pentanoic acid
Butanecarboxylate
Butanecarboxylic acid
CH3-[CH2]3-COOH
Kyselina valerova
n-BuCOOH
n-C4H9COOH
n-Pentanoate
n-Pentanoic acid
n-Valerate
n-valeric acid
Pentanoate
Pentanoic acid
pentoate
pentoic acid
Propylacetate
Propylacetic acid
Valerate
Valerianate
Valerianic acid
Valeriansaeure
Valeriansaure
Valeric acid
Valeric acid normal
Valeric acid, n-
Valeric acid, normal
Valerate, normal
N-Pentanoic acid, ammonium salt
N-Pentanoic acid, potassium salt
N-Pentanoic acid, sodium salt
N-Pentanoic acid, zinc salt
N-Pentanoic acid, maganese (+2) salt
N-Pentanoic acid, 11C-labeled
Lithium pentanoate
N-Pentanoic acid, 11C-labeled sodium salt
VANILIN
Vanillin is an organic compound with the molecular formula C8H8O3.
Vanillin is the primary component of the extract of the vanilla bean, giving it its distinctive aroma and flavor.
Vanillin is commonly used as a flavoring agent in foods, beverages, and pharmaceuticals, as well as in perfumes and fragrances.

CAS Number: 121-33-5
Molecular Formula: C8H8O3
Molecular Weight: 152.15
EINECS Number: 204-465-2

Synonyms: vanillin, 4-Hydroxy-3-methoxybenzaldehyde, 121-33-5, Vanillaldehyde, Vanillic aldehyde, p-Vanillin, Lioxin, Vanilline, Vanilla, 3-Methoxy-4-hydroxybenzaldehyde, 4-Hydroxy-m-anisaldehyde, 2-Methoxy-4-formylphenol, Benzaldehyde, 4-hydroxy-3-methoxy-, Zimco, p-Hydroxy-m-methoxybenzaldehyde, 4-Hydroxy-3-methoxy-benzaldehyde, Methylprotocatechuic aldehyde, 4-Formyl-2-methoxyphenol, Vanilin, Vanillin (natural), 4-Hydroxy-5-methoxybenzaldehyde, m-Anisaldehyde, 4-hydroxy-, Protocatechualdehyde, methyl-, FEMA No. 3107, vaniline, Rhovanil, Protocatechualdehyde 3-methyl ether, Vanillin (NF), NSC 15351, CCRIS 2687, Vanillin Melting Point Standard, HSDB 1027, Vanillin, natural, EINECS 204-465-2, NSC-15351, NSC-48383, Vanillin [NF], NSC-403658, UNII-CHI530446X, BRN 0472792, m-Methoxy-p-hydroxybenzaldehyde, Vanillin (Standard), CHEBI:18346, 4-hydroxy-3-methoxy-benzyldehyde, AI3-00093, NPLC-0145, CHI530446X, MFCD00006942, CHEMBL13883, DTXSID0021969, EC 204-465-2, H-0264, 4-08-00-01763 (Beilstein Handbook Reference), NSC15351, 4-HYDROXY,3-METHOXY-BENZALDEHYDE, NCGC00091645-03, 4-hydroxy-3-methoxybenzaldehyde (vanillin), VANILLIN (II), VANILLIN [II], VANILLIN (MART.), VANILLIN [MART.], WLN: VHR DQ CO1, Vanillin [USAN], DTXCID301969, VANILLIN (EP MONOGRAPH), VANILLIN [EP MONOGRAPH], Vanillinum, VANILLIN (METHOXY-13C), Oleoresin vanilla, Vanilla oleoresin, CAS-121-33-5, 3-methoxy-4-hydroxy-benzaldehyde, oleo-Resins vanilla, V55, Vanillin sodium salt, VANILLIN [FHFI], VANILLIN [HSDB], FEMA Number 3107, oleo-Resins vanilla-bean, VANILLIN [FCC], 4-Hydroxy-3-methoxybenzaldehyde(Vanilline), VANILLIN [MI], VANILLIN [VANDF], methyl-Protocatechualdehyde, bmse000343, bmse000597, bmse010006, Methylprotcatechuic aldehyde, VANILLIN [USP-RS], VANILLIN [WHO-DD], SCHEMBL1213, MLS002303069, BIDD
, Vanillin, puriss., 99.5%, GTPL6412, SGCUT00016, 4-hydroxy 3-methoxybenzaldehyde, METHYLPROTOCATECHUALDEHYDE, HY-N0098R, Vanilla oleoresin (vanilla SPP), 3-methoxy-4-hydroxy benzaldehyde, 4-hydroxy-3-methoxy benzaldehyde, VANILLIN, NATURAL [FHFI], 3-methoxy-4-hydroxy benzoaldehyde, Vanillin, ReagentPlus(R), 99%, 4-hydroxy-3-(methoxy)benzaldehyde, HMS3651D20, HMS3885K07, Vanillin, >=97%, FCC, FG, 4-hydoxy-3-(methyloxy)benzaldehyde, BCP29943, HY-N0098, NSC48383, STR01001, to_000089, Tox21_113534, Tox21_201925, Tox21_300352, 4-hydoxy-3-(methyloxy)benz aldehyde, BBL011956, BDBM50177405, MFCD08702848, NSC403658, s3071, STK199262, AKOS000118929, Tox21_113534_1, CCG-266230, CS-W020052, Vanillin, tested according to Ph.Eur., NCGC00091645-01, NCGC00091645-02, NCGC00091645-04, NCGC00091645-05, NCGC00091645-07, NCGC00254468-01, NCGC00259474-01, Vanillin, natural, >=97%, FCC, FG, AC-10370, BP-10602, NCI60_001085, SMR000156285, SY224451, Vanillin 1000 microg/mL in Acetonitrile, Vanillin, JIS special grade, >=98.0%, Vanillin, Vetec(TM) reagent grade, 98%, 3-Methoxy-4-hydroxybenzaldehyde (vanillin), DB-003805, AM20060497, CS-0694801, H0264, NS00009754, SW219190-1, V0080, EN300-18281, vanillin (3-methoxy-4-hydroxy- benzaldehyde), A19444, C00755, D00091, Q33495, 4-Hydroxy-3-methoxybenzaldehyde inclusion complex, Vanillin (83 degrees C) Melting Point Standard, 4-hydroxy-3-methoxy-Benzaldehyde-5-chlorovanillin, 4-hydroxy-3-methoxybenzaldehyde (ACD/Name 4.0), AC-907/21098004, Q-100102, Vanillin, TraceCERT(R), certified reference material, Z57772449, F2190-0587, Vanillin, European Pharmacopoeia (EP) Reference Standard, Mettler-Toledo Calibration substance ME 51143093, Vanillin, Vanillin, United States Pharmacopeia (USP) Reference Standard, NSC 15351;NSC-15351; NSC15351 pound>>4-Hydroxy-3-methoxybenzaldehyde, Vanillin, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H, Vanillin Melting Point Standard, United States Pharmacopeia (USP) Reference Standard, Mettler-Toledo Calibration substance ME 51143093, Vanillin, traceable to primary standards (LGC), Vanillin melting point standard, Pharmaceutical Secondary Standard; Certified Reference Material.

Vanillin also has applications in the synthesis of other chemicals.
Vanillin is an organic compound with the molecular formula C8H8O3.
Vanillin is a phenolic aldehyde. Its functional groups include aldehyde, hydroxyl, and ether.

Vanillin is the primary component of the extract of the vanilla bean.
Synthetic vanillin is now used more often than natural vanilla extract as a flavoring in foods, beverages, and pharmaceuticals.
Vanillin and ethylvanillin are used by the food industry; ethylvanillin is more expensive, but has a stronger note.

Vanillin differs from vanillin by having an ethoxy group (−O−CH2CH3) instead of a methoxy group (−O−CH3).
Natural vanilla extract is a mixture of several hundred different compounds in addition to vanillin.
Artificial vanilla flavoring is often a solution of pure vanillin, usually of synthetic origin.

Because of the scarcity and expense of natural vanilla extract, synthetic preparation of its predominant component has long been of interest.
The first commercial synthesis of vanillin began with the more readily available natural compound eugenol (4-allyl-2-methoxyphenol).
Today, artificial vanillin is made either from guaiacol or lignin.

Lignin-based artificial vanilla flavoring is alleged to have a richer flavor profile than that from guiacol-based artificial vanilla; the difference is due to the presence of acetovanillone, a minor component in the lignin-derived product that is not found in vanillin synthesized from guaiacol.
The primary natural source of vanillin is the seed pods of the vanilla orchid (Vanilla planifolia). The beans undergo a curing process to develop the characteristic vanilla flavor.
Vanilla Extract: Made by macerating and percolating vanilla beans in a solution of ethanol and water.

Historically, vanillin was synthesized from lignin, a complex organic polymer found in wood, as a byproduct of the paper industry.
Currently, most synthetic vanillin is produced from guaiacol, a compound derived from petrochemicals.
Advances in biotechnology have enabled the production of vanillin through microbial fermentation.

Microorganisms such as bacteria and fungi are engineered to convert natural precursors like ferulic acid (found in rice bran and corn) into vanillin.
Vanillin is the artificial synthesis of the first kind of flavor, synthesized by the German M. Harman, and G-Dr.
Usually It is divided into methyl vanillin and ethyl vanillin.

White or slightly yellow crystalline, with vanilla aroma and rich milk fragrance, is the largest varieties of perfume industry, is the main ingredients of universal favorite creamy vanilla flavor.
Its use is very extensive, such as in food, chemical, tobacco industry as spices, flavoring agent or a flavor enhancer, which is the majority in food consumption of drinks, candy, cakes, biscuits, bread and roasted seeds.
There are no relevant reports that vanillin was harmful to the human body.

Similar to vanilla beans, aroma than methyl vanillin thicker.
Vanillin is a broad-spectrum flavors, which is one of the world's most important synthetic spice, is an important and indispensable raw material for food additives industry.
The aroma is 3-4 times than the vanillin, with aromas of vanilla bean aroma and long-lasting fragrance.

Widely used in food, chocolate, ice cream, drinks and cosmetics play aroma and flavour.
Also ethyl vanillin also is feed additives, electroplating industry of brightening agent, the pharmaceutical industry of intermediates.
Vanillin route By using guaiacol and glyoxylic acid as raw material then by condensation, oxidation and decarboxylation made to vanillin.

This method is mainly composed of French Rhone-Poulenc company research and development, and production in large scale.
The use of glyoxylic acid from maleic acid methyl ester was prepared by two ozone decomposition.
The synthetic route has the advantages of wide material source, less reaction steps, low cost, less three wastes pollution.

Therefore, Vanillin is considered to be the most appropriate method.
Vanillin is a member of the orchid family, a sprawling conglomeration of some 25,000 different species.
Vanillin is a native of South and Central America and the Caribbean; and the first people to have cultivated it seem to have been the Totonacs of Mexico’s east coast.

The Aztecs acquired vanilla when they conquered the Totonacs in the 15th Century; the Spanish, in turn, got it when they conquered the Aztecs.
Vanillin is a complex blend of flavour and fragrance ingredients extracted from the seed pods of the vanilla orchid, containing at a guess somewhere between 250 and 500 different flavor and fragrance components.
The most important ingredient in this blend is vanillin.

However, because of the cost and supply chain variability of natural Vanillin, most products that want to impart the aroma of vanilla do not in fact use vanilla but rather synthetic vanillin (99% of all vanillin consumed worldwide) made primarily from petrochemicals or chemically derived from lignin.
Vanillin is mainly used as a flavouring agent, primarily in foods and beverages such as chocolate and dairy products, but also to mask unpleasant tastes in medicines or livestock fodder.
Vanillin is also an intermediate in the manufacture of certain pharmaceuticals and agrochemicals.

Vanillin and vanilla extracts have an estimated annual total volume of 16,000 metric tonnes, worth some USD 650 million in total.
Natural vanilla extract represents less than 1% by volume, though it is more important in terms of value.
Sales prices range from about USD 1,500 per kg for natural vanilla extract to USD 10-20 per kg for synthetic vanillin.

The primary market opportunity is in providing a competitively priced product, with good aroma properties, made from a natural and sustainable source.
Evolva believes such properties will allow fermentation-derived vanillin to be used in a wide variety of food and other products.
Evolva does not believe that such a product will significantly replace vanilla obtained from the orchid.

Vanillin is commonly known as vanilla powder, cloud Nepal with powder, vanilla extract, is extracted from the Rutaceae vanilla bean, is a kind of important spices, is one of synthetic fragrances yield the largest varieties, mixing chocolate, ice cream, chewing gum, pastry and tobacco essence of important raw materials.
Naturally occurring in pods of vanilla planifolia, and clove oil, oakmoss oil, balsam of Peru, tolu balsam storax.
Vanillin has strong and unique vanilla bean aroma, aroma stability, under the high temperature, less volatile.

Vanillin is vulnerable to light, and gradually oxidized in the air, easy to change color at encountering alkali or alkaline material.
Aqueous solution reacts with ferric chloride to produce blue purple solution.
Can be used for many fragrance formulas, but mainly used for edible essence.

Especially widely used in the candy, chocolate, soft drinks, ice cream, wine, and in the smoke flavor.
There is no restrictions imposed on the use of IFRA.
But because of easy cause discoloration, should pay attention to use in white fragrant product.

Vanillin is also an important foundation for edible spices, spices, almost all flavors, most used in food industry.
Food flavors are widely used in bread, butter, cream and brandy etc.
The addition amount of cakes, biscuits is 0.01~0.04%, candy is 0.02~0.08%, which is one of the most the baked food with spices, can be used for chocolate, biscuit, cake, ice cream and Boudin.

Before use, Vanillin is dissolved in warm water, the effect is much better.
The highest amount of baked food is 220mg/kg, chocolate is 970mg/kg.
As fixative agent, coordination agent and modifier are widely used in cosmetics, also is the important flavoring agent for food and drink.

Vanillin is used in medicine.
Also used for nickel, chrome metal plating brightener.
Vanillin has strong and unique vanilla beans, naturally found in vanilla and clove oil, oil, oakmoss, balsam of Peru, and the rest of tolu balsam.

Sulfite solution or red pulp softwood lignin sulfonate, under the alkaline conditions, reacted by high-pressure oxidation hydrolysis precipitation to get white to light yellow crystalline powder or acicular crystal.
From petroleum ether precipitation can also generate tetragonal crystal.
Vanillin has Aroma, Bitter sweet.

In the air, Vanillin is gradually oxidized.
In case of light, Vanillin generated decomposition.
In case of alkali, it generated discoloration.

The relative molecular mass is 152.15.
The relative density is 1.056.
Vanillin can generate sublimation without decomposition.

Slightly soluble in cold water, soluble in hot water, soluble in ethanol, ethyl ether, propylene Ketone, benzene, chloroform, carbon disulfide, glacial acetic acid, pyridine and volatile oil.
Water and FeCl3 generate blue purple solution.
For rats, by oral LD 50 1580mg/kg, mice is by percutaneous LD 50 1500mg/kg.
Industrial production method is that eugenol in the presence of potassium hydroxide, produce to ISO eugenol, then reacted with acetic anhydride formation of isoeugenol acetate, followed by oxidation and hydrolysis reaction to produce.

Vanillin is an important raw material for mixing chocolate, ice cream, chewing gum the pastry and tobacco flavor.
Vanillin can also be used as cosmetics fragrance coordination agent and a flavor enhancer.
Vanillin is also the pharmaceutical raw materials of industry.

In recent years, Vanillin appeared a new fashion in the commodity of vanillin.
Use oil of clove or basil oil provided out of eugenol as raw material, vanillin obtained by isomerization and oxidation, as it can be regarded as a natural equivalent quality, therefore it is called natural vanillin and into the spice market, its price is about 5 times that of the synthetic product.
Vanillin is found in many essential oils and foods but is often not essential for their odor or aroma.

However, it does determine the odor of essential oils and extracts from Vanilla planifolia and Vanilla tahitensis pods, in which it is formed during ripening by enzymatic cleavage of glycosides.
Vanillin is a colorless, crystalline solid (mp 82–83°C) with a typical vanilla odor.
Because it possesses aldehyde and hydroxy substituents, it undergoes many reactions.

Additional reactions are possible due to the reactivity of the aromatic nucleus.
Vanillin alcohol and 2-methoxy-4-methylphenol are obtained by catalytic hydrogenation; vanillic acid derivatives are formed after oxidation and protection of the phenolic hydroxy group.
Since vanillin is a phenol aldehyde, it is stable to autoxidation and does not undergo the Cannizzaro reaction.

Numerous derivatives can be prepared by etherification or esterification of the hydroxy group and by aldol condensation at the aldehyde group.
Several of these derivatives are intermediates, for example, in the synthesis of pharmaceuticals.
White or light yellow needle crystal or crystal powder, with a strong aroma.

Vanillin is not only soluble in ethanol, chloroform, ether, carbon disulfide, glacial acetic acid, and pyridine but also in oil, propylene glycol, and hydrogen peroxide in alkaline solution.
Vanillin can slowly oxidize in the air, can be unstable under illumination, and should be stored in a dark condition.
Vanillin occurs widely in nature; it has been reported in the essential oil of Java citronella (Cymbopogon nardus Rendl.), in benzoin, Peru balsam, clove bud oil and chiefly vanilla pods (Vanilla planifolia, V. tahitensis, V. pompona); more that 40 vanilla varieties are cultivated; vanillin is also present in the plants as glucose and vanillin.

Reported found in guava, feyoa fruit, many berries, asparagus, chive, cinnamon, ginger, Scotch spearmint oil, nutmeg, crisp and rye bread, butter, milk, lean and fatty fish, cured pork, beer, cognac, whiskies, sherry, grape wines, rum, cocoa, coffee, tea, roast barley, popcorn, oatmeal, cloudberry, passion fruit, beans, tamarind, dill herb and seed, sake, corn oil, malt, wort, elderberry, loquat, Bourbon and Tahiti vanilla and chicory root.
Vanillin is known as one of the first synthetic spices.
In the perfume industry, it is known as vanillic aldehyde.

As early as 1858, French chemist Gby (NicolasTheodore Gobley) obtained pure vanillin for the first time by the method of rectification.
Due to less production yield of natural vanillin, it spurred the search for a chemical synthesis method of vanillin production.
In 1874, German scientist M.Haarman and co-workers deduced the chemical structure of vanillin and discovered a new way to produce vanillin with abietene as the raw material .

In 1965, Chinese scientists found that vanillin has antiepileptic effect and accomplished a study on the pharmacology and toxicology of vanillin from edible to officinal.
They also found that vanillin has certain antibacterial activity, making it a suitable drug formulation for the treatment of skin disease.
Vanillin can be used as intermediate for synthesis of a variety of drugs, such as berberine and antihypertensive drug L-methyldopa, methoxy-pyrimidine, and heart disease drug papaverine .

Commercial vanillin is obtained by processing waste sulfite liquors or is synthesized from guaiacol.
Preparation by oxidation of isoeugenol is of historical interest only.
The starting material for vanillin production is the lignin present in sulfite wastes from the cellulose industry.

The concentrated mother liquors are treated with alkali at elevated temperature and pressure in the presence of oxidants.
The vanillin formed is separated from the by-products, particularly acetovanillone (4-hydroxy-3- methoxyacetophenone), by extraction, distillation, and crystallization.
A large number of patents describe various procedures for the (mainly) continuous hydrolysis and oxidation processes, as well as for the purification steps required to obtain high-grade vanillin .

Lignin is degraded either with sodium hydroxide or with calcium hydroxide solution and simultaneously oxidized in air in the presence of catalysts.
When the reaction is completed, the solid wastes are removed.
Vanillin is extracted from the acidified solutionwith a solvent (e.g., butanol or benzene) and reextractedwith sodium hydrogen sulfite solution.

Reacidification with sulfuric acid followed by vacuum distillation yields technical-grade vanillin, which must be recrystallized several times to obtain food-grade vanillin.
Water, to which some ethanol may be added, is used as the solvent in the last crystallization step.
Severalmethods can be used to introduce an aldehyde group into an aromatic ring.

Condensation of guaiacol with glyoxylic acid followed by oxidation of the resulting mandelic acid to the corresponding phenylglyoxylic acid and, finally, decarboxylation continues to be a competitive industrial process for vanillin synthesis.
Vanillin from guaiacol and glyoxylic acid: Currently, guaiacol is synthesized from catechol, which is mainly prepared by acid-catalyzed hydroxylation of phenol with hydrogen peroxide.
In China, a guaiacol prepared from o-nitrochlorobenzene via o-anisidine is also used.

Vanillin is obtained as a by-product in the synthesis of glyoxal from acetaldehyde and can also be produced by oxidation of glyoxal with nitric acid.
Condensation of guaiacol with glyoxylic acid proceeds smoothly at room temperature and in weakly alkaline media.
A slight excess of guaiacol is maintained to avoid formation of disubstituted products; excess guaiacol is recovered.

The alkaline solution containing Vanillin is then oxidized in air in the presence of a catalyst until the calculated amount of oxygen is consumed.
Crude vanillin is obtained by acidification and simultaneous decarboxylation of the (4-hydroxy-3-methoxyphenyl)glyoxylic acid solution.
This process has the advantage that, under the reaction conditions, the glyoxyl radical enters the aromatic guaiacol ring almost exclusively para to the phenolic hydroxy group.

Tedious separation procedures are thus avoided. b. Vanillin from guaiacol and formaldehyde: An older process that is still in use consists of the reaction of guaiacolwith formaldehyde or formaldehyde precursors such as urotropine, N,N-dimethyl-aniline, and sodium nitrite .
Vanillin occurs naturally in many essential oils and particularly in the pods of Vanilla planifolia and Vanilla tahitensis.
Industrially, vanillin is prepared from lignin, which is obtained from the sulfite wastes produced during paper manufacture.

Lignin is treated with alkali at elevated temperature and pressure, in the presence of a catalyst, to form a complex mixture of products from which vanillin is isolated.
Vanillin is then purified by successive recrystallizations.
Vanillin may also be prepared synthetically by condensation, in weak alkali, of a slight excess of guaiacol with glyoxylic acid at room temperature.

The resultant alkaline solution, containing 4- hydroxy-3-methoxymandelic acid is oxidized in air, in the presence of a catalyst, and vanillin is obtained by acidification and simultaneous decarboxylation.
Vanillin is then purified by successive recrystallizations.
Vanillin is an indispensable assistant for dessert and cake recipes with its distinguished aroma.

Melting point: 81-83 °C(lit.)
Boiling point: 170 °C15 mm Hg(lit.)
Density: 1.06
vapor density: 5.3 (vs air)
vapor pressure: >0.01 mm Hg ( 25 °C)
refractive index: 1.4850 (estimate)
FEMA: 3107 | VANILLIN
Flash point: 147 °C
storage temp.: 2-8°C
solubility: methanol: 0.1 g/mL, clear
pka: pKa 7.396±0.004(H2O I = 0.00 t = 25.0±1.0) (Reliable)
form: Crystalline Powder
color: White to pale yellow
PH: 4.3 (10g/l, H2O, 20℃)
Odor: at 100.00 %. vanilla
Odor Type: vanilla
Water Solubility: 10 g/L (25 ºC)
Sensitive: Air & Light Sensitive
JECFA Number: 889
Merck: 14,9932
BRN: 472792
Stability: Stable. May discolour on exposure to light. Moisture-sensitive. Incompatible with strong oxidizing agents, perchloric acid.
LogP: 1.17 at 25℃

Vanillin is edible flavouring agent, with vanilla bean aroma and strong desire for milk fragrance, is an important and indispensable raw material for food additives industry, widely used in all need to increase milk fragrance flavor flavoring in food, such as cake, cold drinks, chocolate, candy, biscuits, instant noodles, bread and tobacco, flavoring liquor, toothpaste, soap, cosmetics, perfume, ice cream, drinks and cosmetics play aroma and flavour.
Also Vanillin can be used for soap, toothpaste, perfume, rubber, plastic, pharmaceutical products.
Vanillin Accord with FCCIV standard.

Vanitrope has a strong and enduring clove and vanilla aroma, the aroma intensity is from 16 to 25 times of vanillin. Vanitrope was early developed.
Early synthetic route is that safrole oil as raw material, the alcohol solution of potassium hydroxide reacted hot pressing enable to open ring, and then used sodium ethyl sulfate to make the hydroxy ethylation, finally in the ethanol solution with sulfuric acid hydrolysis to obtain the vanitrope.
But due to the lack purity of aroma of the product, so it is very little actual application.

In the fifties of the 20th century, Vanillin developed from eugenol preparation of vanitrope synthetic route, only then can realize the industrial production.
Catechol flavor chemists,successfully developed by more cheap raw materials of pyrocatechol in the Soviet Union in 1960s.
First with allyl chloride to catechol mono alkylation, and the yield is 75%; followed by rearrangement reaction and yield is 35%~38%; then by using ethyl sodium sulfate for single ethylation, yield is 82%.

Finally with potassium hydroxide isomerization will get vanitrope, yield is 84%, after recrystallization of the crude product melting point 85.5 to 86℃.
Vanillin applied in candy, beverage, ice cream and other food flavoring formulations, the FEMA number is 2922.
Vanillin also can be used in cosmetics and soap fragrance formula.

Vanillin not only can used as a spice, but also can be used as a synergistic agent and antioxidant.
Former Soviet Union perfumers hold different views of vanitrope aroma properties.
They added it to the chocolate and other food flavor.

Vanillin is found that the goods are not vanillin aroma, so that it cannot in the flavor of food as a substitute for vanillin.
But when used for flavoring test of scented soap, found that soap has strong clove and vanilla aroma like it.
The differences with vanillin and isoeugenol, vanitrope to alkali, light, oxidation is very stable, soap like storage does not change color.

Therefore Vanillin should be used in fragrance formulations, particularly appropriate for fantasy flavor.
A great variety of Vanillin plants bearing the vanilla pods, or siliques, exist.
Those mentioned above are the most important species.

Of special value are those cultivated in Mexico, Madagascar, Java, Tahiti, the Comoro Islands and Réunion.
The cultivation of vanilla beans is very long and laborious.
The plant is a perennial herbaceous vine that grows up to 25 m in height and needs suitable supports in order to grow.

Fecundation of flowers is performed (November to December) by perforating the membrane that separates the pollen from the pistil.
This is an exacting task requiring skilled hand labor.
Natural fecundation occurs when a similar operation is carried out by birds or insects that perforate the membrane in search of food.

After a few months, clusters of hanging pods (siliques) are formed; these start to yellow at the lower tip from August to September.
At this point, the siliques are harvested and undergo special treatment that develops the aroma.
The Vanillins are placed in straw baskets and dipped into hot water to rupture the inner cell wall.

After a few months, the aroma starts developing.
Then the siliques are exuded by intermittent exposure to sunlight (by alternately covering and uncovering the siliques with wool blankets).
When exudation is complete, the Vanillins are oiled with cocoa oil to avoid chapping during drying and are finally dried to a suitable residual moisture content.

In the final stage of the preparation, the best quality siliques form a Vanillin “brine” that crystallizes on the surface of the bean.
Generally, the processing of vanilla bean takes more than a year.
The most important commercial qualities are brined vanilla, bastard vanilla and vanilla pompona.

The bean is the only part used. Vanilla has a sweet, ethereal odor and characteristic flavor.
In addition to vanillin (approximately 3%), vanilla contains other aromatic principles: vanillin, piperonal, eugenol, glucovanillin, vanillic acid, anisic acid and anisaldehyde.
Although vanillin is associated with the characteristic fragrance of the plant, the quality of vanilla bean is not associated with the vanillin content.

Bourbon beans contain a high amount of vanillin compared to Mexican and Tahiti beans.
In addition to vanillin (approximately 3%), vanilla contains other aromatic principles: vanillin, piperonal, eugenol, glucovanillin, vanillic acid, anisic acid and anisaldehyde.
Although vanillin is associated with the characteristic fragrance of the plant, the quality of vanilla bean is not associated with the vanillin content.

Bourbon beans contain a high amount of vanillin compared to Mexican and Tahiti beans.
Vanillin is most prominent as the principal flavor and aroma compound in vanilla.
Cured vanilla pods contain about 2% by dry weight vanillin.

On cured pods of high quality, relatively pure vanillin may be visible as a white dust or "frost" on the exterior of the pod.
Vanillin is also found in Leptotes bicolor, a species of orchid native to Paraguay and southern Brazil, and the Southern Chinese red pine.
At lower concentrations, vanillin contributes to the flavor and aroma profiles of foodstuffs as diverse as olive oil, butter, raspberry, and lychee fruits.

Aging in oak barrels imparts vanillin to some wines, vinegar, and spirits.
In other foods, heat treatment generates vanillin from other compounds.
In this way, vanillin contributes to the flavor and aroma of coffee, maple syrup, and whole-grain products, including corn tortillas and oatmeal.

Vanillin can trigger migraine headaches in a small fraction of the people who experience migraines.
Some people have allergic reactions to Vanillin.
They may be allergic to synthetically produced vanilla but not to natural vanilla, or the other way around, or to both.

Vanillin orchid plants can trigger contact dermatitis, especially among people working in the vanilla trade if they come into contact with the plant's sap.
An allergic contact dermatitis called vanillism produces swelling and redness, and sometimes other symptoms.
The sap of most species of vanilla orchid which exudes from cut stems or where beans are harvested can cause moderate to severe dermatitis if it comes in contact with bare skin.

The sap of vanilla orchids contains calcium oxalate crystals, which are thought to be the main causative agent of contact dermatitis in vanilla plantation workers.
Vanillin is widely used to impart vanilla flavor to a variety of products including ice cream, chocolate, baked goods, and beverages.
Enhances the sweetness perception and complexity of flavors in foods.

Vanillin utilized as a key note in many fragrances, providing a warm, sweet, and creamy scent.
Incorporated in lotions, creams, and other personal care products for its pleasant aroma.
Vanillin is used to mask unpleasant tastes in oral medications and supplements.

Acts as a precursor or intermediate in the synthesis of various pharmaceutical compounds.
Vanillin is used as a starting material in the synthesis of other organic compounds, including pharmaceuticals and agrochemicals.
Employed as a reference material for calibrating instruments in analytical chemistry due to its well-defined properties.

Some research indicates potential use in insect repellent formulations.
Valued in aromatherapy for its calming and soothing properties.
Vanillin is listed as GRAS by the U.S. Food and Drug Administration (FDA), meaning it is considered safe for consumption in regulated amounts.

Although rare, some individuals may have allergies to vanillin or natural vanilla extracts.
Efforts are ongoing to develop more sustainable and eco-friendly methods of producing vanillin, such as utilizing renewable resources and minimizing waste in the production process.
The use of genetically engineered microorganisms to produce vanillin is seen as a promising sustainable alternative to traditional synthetic methods.

History:
Although Vanillin is generally accepted that vanilla was domesticated in Mesoamerica and subsequently spread to the Old World in the 16th century, in 2019, researchers published a paper stating that vanillin residue had been discovered inside jars within a tomb in Israel dating to the 2nd millennium BCE, suggesting the possible cultivation of an unidentified, Old World-endemic Vanilla species in Canaan since the Middle Bronze Age.
Traces of vanillin were also found in wine jars in Jerusalem, which were used by the Judahite elite before the city was destroyed in 586 BCE.

Vanillin beans, called tlilxochitl, were discovered and cultivated as a flavoring for beverages by native Mesoamerican peoples, most famously the Totonacs of modern-day Veracruz, Mexico. Since at least the early 15th century, the Aztecs used vanilla as a flavoring for chocolate in drinks called xocohotl.
Vanillin was first isolated as a relatively pure substance in 1858 by Théodore Nicolas Gobley, who obtained it by evaporating a vanilla extract to dryness and recrystallizing the resulting solids from hot water.

In 1874, the German scientists Ferdinand Tiemann and Wilhelm Haarmann deduced its chemical structure, at the same time finding a synthesis for vanillin from coniferin, a glucoside of isoeugenol found in pine bark.
Tiemann and Haarmann founded a company Haarmann and Reimer (now part of Symrise) and started the first industrial production of vanillin using their process (now known as the Reimer–Tiemann reaction) in Holzminden, Germany.
In 1876, Karl Reimer synthesized vanillin (2) from guaiacol (1).

By the late 19th century, semisynthetic vanillin derived from the eugenol found in clove oil was commercially available.
Synthetic vanillin became significantly more available in the 1930s, when production from clove oil was supplanted by production from the lignin-containing waste produced by the sulfite pulping process for preparing wood pulp for the paper industry.
By 1981, a single pulp and paper mill in Thorold, Ontario, supplied 60% of the world market for synthetic vanillin.

However, subsequent developments in the wood pulp industry have made its lignin wastes less attractive as a raw material for vanillin synthesis.
Today, approximately 15% of the world's production of vanillin is still made from lignin wastes, while approximately 85% synthesized in a two-step process from the petrochemical precursors guaiacol and glyoxylic acid.

Beginning in 2000, Rhodia began marketing biosynthetic vanillin prepared by the action of microorganisms on ferulic acid extracted from rice bran.
At USD$700/kg, this product, sold under the trademarked name Rhovanil Natural, is not cost-competitive with petrochemical vanillin, which sells for around US$15/kg.
However, unlike vanillin synthesized from lignin or guaiacol, it can be labeled as a natural flavoring.

Uses:
Vanillin is used as a flavor, fragrance, pharmaceutical intermediates.
Vanillin is to obtain the incense powder, bean fragrant spices. Often used in the fragrance foundation with.
Vanillin is widely used in almost all the flavor that doubles as a combination of such as violet, Cymbidium, sunflower, Oriental flavor.

In edible, smoke flavor as well as wide application, but the amount is larger.
In Vanillin bean type, cream, chocolate, too Princess flavor are need to use spices.
Vanillin is China's regulations allow the use of edible spices, as a fixative agent, is the preparation of the main raw material of vanilla flavor.

Vanillin can also be directly used in biscuits, cakes, candy, drinks and other food flavoring.
Dosage according to the normal production needs, generally in the chocolate 970mg/kg; 270mg/kg in chewing gum; 220mg/kg in pastry, biscuit; 200mg/kg in candy; 150mg/kg in condiment~95mg/kg in cold drinks.
Widely used in the preparation of vanilla, chocolate, butter flavor, the amount is up to 25%~30%, or directly used in biscuits, pastries, dosage is 0.1%~0.4%, cold drink is 0.01%~0.3%, candy is 0.2%~0.8%, especially containing dairy products.

An important synthetic fragrance, widely used in daily life activities.
Vanillin is used as food, tobacco and wine with a fine wisely.
In the food industry usage amount is large for the preparation of the vanilla, chocolate, butter flavor, the amount is up to 25-30%, directly on a cookie, cake, dosage is 0.1-0.4%, cold is 0.01-0.3%, candy is 0.2-0.8, especially is containing dairy products.

Vanillin is used for chemical analysis, tests for protein nitrogen heterocyclic indene, phloroglucinol and tannic acid.
In the pharmaceutical industry, it is used for production of antihypertensive drug methyldopa, catechols L-dopa medication, and Catalin and diaveridine.
Vanillin is used as a reagent in organic analysis standard.

Tests for protein, nitrogen heterocyclic indene, pyrogallol, tannic acid, iron ions.
From benzoic acid in the determination of chloride, spices, organic trace analysis determination of methoxy standard.
Vanillin is a flavorant made from synthetic or artificial vanilla which can be derived from lignin of whey sulfite liquors and is syntheti- cally processed from guaiacol and eugenol.

The related product, ethyl vanillin, has three and one-half times the flavoring power of vanillin.
Vanillin also refers to the primary flavor ingredient in vanilla, which is obtained by extraction from the vanilla bean.
Vanillin is used as a substitute for vanilla extract, with application in ice cream, desserts, baked goods, and beverages at 60–220 ppm.

Occurs naturally in a wide variety of foods and plants such as orchids; major commercial source of natural vanillin is from vanilla bean extract.
Synthetically produced in-bulk fro m lignin-based byproduct of paper processes or from guaicol.
Vanillin is widely used as a flavor in pharmaceuticals, foods, beverages, and confectionery products, to which it imparts a characteristic taste and odor of natural vanilla.

Vanillin is also used in perfumes, as an analytical reagent and as an intermediate in the synthesis of a number of pharmaceuticals, particularly methyldopa.
Additionally, Vanillin has been investigated as a potential therapeutic agent in sickle cell anemia and is claimed to have some antifungal properties.
In food applications, vanillin has been investigated as a preservative.

As a pharmaceutical excipient, vanillin is used in tablets, solutions (0.01–0.02% w/v), syrups, and powders to mask the unpleasant taste and odor characteristics of certain formulations, such as caffeine tablets and polythiazide tablets.
Vanillin is similarly used in film coatings to mask the taste and odor of vitamin tablets.
Vanillin has also been investigated as a photostabilizer in furosemide 1% w/v injection, haloperidol 0.5% w/v injection, and thiothixene 0.2% w/v injection.

The largest use of vanillin is as a flavoring, usually in sweet foods.
The ice cream and chocolate industries together comprise 75% of the market for vanillin as a flavoring, with smaller amounts being used in confections and baked goods.
Vanillin is also used in the fragrance industry, in perfumes, and to mask unpleasant odors or tastes in medicines, livestock fodder, and cleaning products.

Vanillin is also used in the flavor industry, as a very important key note for many different flavors, especially creamy profiles such as cream soda.
Additionally, vanillin can be used as a general-purpose stain for visualizing spots on thin-layer chromatography plates.
This stain yields a range of colors for these different components.

Vanillin–HCl staining can be used to visualize the localisation of tannins in cells.
Vanillin is becoming a popular choice for the development of bio-based plastics.
Vanillin has been used as a chemical intermediate in the production of pharmaceuticals, cosmetics, and other fine chemicals.

In 1970, more than half the world's vanillin production was used in the synthesis of other chemicals.
As of 2016, vanillin uses have expanded to include perfumes, flavoring and aromatic masking in medicines, various consumer and cleaning products, and livestock foods.
Vanillin is used as a vanilla substitute in ice cream, baked goods, beverages, chocolate, confectionery, gelatinous desserts, and many food products.

Vanillin enhances the overall flavor profile and sweetness perception in food products.
Vanillin is used as a base note in many fragrances, providing a warm, sweet, and creamy scent.
It is included in lotions, creams, shampoos, and other personal care products for its pleasant aroma.

Vanillin helps mask unpleasant tastes in oral medications, making them more palatable.
In some cases, vanillin itself may have therapeutic properties, including antioxidant and anti-inflammatory effects.
Vanillin serves as a precursor in the synthesis of certain pharmaceuticals.

Vanillin is a starting material for the synthesis of various chemicals, including:
Vanillin is used as a standard for calibrating analytical instruments due to its well-defined melting point and chemical properties.
Some formulations may include vanillin or its derivatives as active ingredients due to potential insect-repellent properties.

Vanillin is added to cleaning products to provide a pleasant scent.
Vanillin is used in air fresheners and scented candles to create a vanilla aroma.
Vanillin derivatives are used in the production of certain polymers and resins.

Utilized in biotechnological processes for the production of bio-based chemicals.
Vanillin is used in aromatherapy for its calming and soothing effects.
Vanillin has been studied for its potential to act as a natural preservative due to its antioxidant activity.

Vanillin is used in various research applications, including studies on its potential health benefits and its role in food chemistry.
Vanillin is used to improve the taste of dietary supplements and nutraceutical products, making them more palatable for consumers.
Vanillin is added to animal feed to enhance the palatability, encouraging consumption by livestock and pets.

Emerging research suggests that vanillin may have antimicrobial properties, which can help in extending the shelf life of food products.
Vanillin derivatives can be used as fixatives in textile dyeing processes to improve color fastness.
Vanillin is used as a substrate in biocatalysis for the production of other valuable chemicals.

Enzymes that convert vanillin are studied for applications in green chemistry.
Vanillin is used in skin care formulations for its potential antioxidant properties, which can help in protecting the skin from oxidative damage.
Added for flavoring and potential antibacterial effects.

Vanillin-based polymers are being researched for use in environmentally friendly packaging materials.
Vanillin and its derivatives are being studied for their potential use in bioremediation to break down pollutants and toxic substances in the environment.
Research is ongoing into vanillin’s potential health benefits, including its role as an anti-inflammatory and antioxidant agent.

Vanillin-based compounds are being explored for use in drug delivery systems due to their biocompatibility and bioactive properties.
Vanillin is widely used in educational settings as a reagent for chemistry experiments and demonstrations, particularly in organic synthesis labs.
Vanillin is used to flavor tobacco products, including cigarettes and e-cigarettes, to enhance the sensory experience.

Vanillin can be used in the preservation and restoration of artworks, particularly in maintaining the quality of natural resins and varnishes.
Vanillin is a key component in both pure vanilla extract and imitation vanilla flavoring, widely used in home baking and commercial food production.
Vanillin is a popular fragrance used in homemade candles.

Added to soaps and bath products for its fragrance and potential skin benefits.
Vanillin is used as a certified reference material (CRM) for ensuring the quality and accuracy of analytical measurements in laboratories.
Vanillin is included in household cleaning products to provide a pleasant vanilla scent.

Vanillin is used in laundry detergents and fabric softeners to impart a fresh, vanilla fragrance.
Research is exploring vanillin’s potential as a natural pesticide or as a synergist to enhance the effectiveness of other pesticide compounds.

Vanillin is used to flavor protein powders and nutritional shakes, making them more appealing to consumers.
Vanillin is added to fortified foods to improve taste while delivering additional nutrients or health benefits.

Storage:
Vanillin oxidizes slowly in moist air and is affected by light.
Solutions of vanillin in ethanol decompose rapidly in light to give a yellow-colored, slightly bitter tasting solution of 6,6’-dihydroxy- 5,5’-dimethoxy-1,1’-biphenyl-3,3’-dicarbaldehyde.
Alkaline solutions also decompose rapidly to give a brown-colored solution.

However, solutions stable for several months may be produced by adding sodium metabisulfite 0.2% w/v as an antioxidant.
The bulk material should be stored in a well-closed container, protected from light, in a cool, dry place.

Safety Profile
Moderately toxic by ingestion, intraperitoneal, subcutaneous, and intravenous routes.
Experimental reproductive effects.
Human mutation data reported. Can react violently with Br2, HClO4, potassium-tert-butoxide, tert- chlorobenzene + NaOH, formic acid + thallium nitrate.

When heated to decomposition it emits acrid smoke and irritating fumes.
There have been few reports of adverse reactions to vanillin, although it has been speculated that cross-sensitization with other structurally similar molecules, such as benzoic acid, may occur.
Adverse reactions that have been reported include contact dermatitis and bronchospasm caused by hypersensitivity.


VANILIN
Vanilin is an organic compound with the molecular formula C8H8O3.
Vanilin is an intermediate and analytical reagent.
Vanilin is a phenolic aldehyde.


CAS Number: 121-33-5
EC Number: 204-465-2
MDL Number: MFCD00006942
Chemical formula: C8H8O3



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CHI530446X, MFCD00006942, CHEMBL13883, DTXSID0021969, VANILIN (METHOXY-13C), EC 204-465-2, H-0264, 4-08-00-01763 (Beilstein Handbook Reference), NSC15351, 4-HYDROXY,3-METHOXY-BENZALDEHYDE, NCGC00091645-03, 4-hydroxy-3-methoxybenzaldehyde (Vanilin), 86884-84-6, VANILIN (II), VANILIN [II], VANILIN (MART.), VANILIN [MART.], WLN: VHR DQ CO1, Vanilin [USAN], DTXCID301969, VANILIN (EP MONOGRAPH), VANILIN [EP MONOGRAPH], Oleoresin vanilla, Vanilla oleoresin, MFCD08702848, CAS-121-33-5, 3-methoxy-4-hydroxy-benzaldehyde, oleo Resins vanilla, V55, Vanilin sodium salt, VANILIN [FHFI], VANILIN [HSDB], VANILIN [INCI], FEMA Number 3107, oleo-Resins vanilla-bean, VANILIN [FCC], 4-Hydroxy-3-methoxybenzaldehyde(Vaniline), VANILIN [MI], VANILIN [VANDF], methyl-Protocatechualdehyde, bmse000343, bmse000597, bmse010006, Methylprotcatechuic aldehyde, VANILIN [USP-RS], VANILIN [WHO-DD], SCHEMBL1213, MLS002303069, BIDD:ER0330, Vanilin, puriss., 99.5%, GTPL6412, SGCUT00016, 4-hydroxy 3-methoxybenzaldehyde, 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Vanilin (3-methoxy-4-hydroxy- benzaldehyde), 3-Methoxy-4-hydroxybenzaldehyde (Vanilin)



Vanilin appears as a white, crystalline powder.
Vanilin dissolves well in some organic solvents, especially ethyl alcohol.
Vanilin is an organic compound that carries a pleasant vanilla odor and taste.


Vanilin is an indispensable ingredient for all kinds of cakes, cookies, sweet buns, milk and pastries.
Vanilin adds aroma and flavor to your desserts.
Vanilin is a sugary substance.


Vanilin has a pleasant smell.
Vanilin is frequently used by pastry chefs.
Vanilin is often confused with vanilla .


Vanilin is a fragrant and delicious substance used in cakes, cakes, donuts, ice cream, chocolate and desserts.
Vanilin is a chemical product.
Vanilin is obtained by chemical means and a by-product obtained from trees.


Vanilin is a kind of sweet flavoring.
Vanilin appears as white or very slightly yellow needles.
Vanilin is a member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively.


Vanilin has a role as a plant metabolite, an anti-inflammatory agent, a flavouring agent, an antioxidant and an anticonvulsant.
Vanilin is a member of phenols, a monomethoxybenzene and a member of benzaldehydes.
Vanilin is a natural product found in Ficus erecta var beecheyana, Pandanus utilis, and other organisms with data available.


Vanilin is a metabolite found in or produced by Saccharomyces cerevisiae.
As harvested, the green seed pods contain Vanilin in the form of its β-d-glucoside; the green pods do not have the flavor or odor of vanilla.
Vanilin is an organic compound with the molecular formula C8H8O3.


Vanilin is a phenolic aldehyde.
Vanilin's functional groups include aldehyde, hydroxyl, and ether.
Vanilin is the primary component of the extract of the vanilla bean.


Vanilin and ethylVanilin are used by the food industry; ethylVanilin is more expensive, but has a stronger note.
Vanilin differs from Vanilin by having an ethoxy group (−O−CH2CH3) instead of a methoxy group (−O−CH3).
Vanilin is a mixture of several hundred different compounds in addition to Vanilin.


Vanilin flavoring is often a solution of pure Vanilin, usually of synthetic origin.
Because of the scarcity and expense of Vanilin, synthetic preparation of its predominant component has long been of interest.
The first commercial synthesis of Vanilin began with the more readily available natural compound eugenol (4-allyl-2-methoxyphenol).


Today, Vanilin is made either from guaiacol or lignin.
Vanilin crystals extracted from vanilla extract
Lignin-based artificial vanilla flavoring is alleged to have a richer flavor profile than oil-based flavoring; the difference is due to the presence of acetovanillone, a minor component in the lignin-derived product that is not found in Vanilin synthesized from guaiacol.


Vanilin is a white, crystalline needles; sweetish smell.
Vanilin is soluble in 125 parts water, 20 parts glycerol, and 2 parts 95% alcohol; soluble in chloroform and ether.
Vanilin is a white needle-like crystals. Aromatic odor.


Vanilin (p-Vanilin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.
Vanilin is a white crystals or slightly yellow needles with vanilla, sweet, balsamic and pleasant odor
Vanilin is a phenolic aldehyde, which is an organic compound with the molecular formula C8H8O3.


Vanilin's functional groups include aldehyde, hydroxyl, and ether.
Vanilin is the primary component of the extract of the vanilla bean.
anillin and ethylVanilin are used by the food industry; ethylVanilin is more expensive, but has a stronger note.


It differs from Vanilin by having an ethoxy group (–O–CH2CH3) instead of a methoxy group (–O–CH3).
Natural "vanilla extract" is a mixture of several hundred different compounds in addition to Vanilin.
Artificial vanilla flavoring is often a solution of pure Vanilin, usually of synthetic origin.


Because of the scarcity and expense of natural vanilla extract, synthetic preparation of Vanilin's predominant component has long been of interest.
The first commercial synthesis of Vanilin began with the more readily available natural compound eugenol.
Today, artificial Vanilin is made either from guaiacol or lignin.


Lignin-based artificial vanilla flavoring is alleged to have a richer flavor profile than oil-based flavoring; the difference is due to the presence of acetovanillone, a minor component in the lignin-derived product that is not found in Vanilin synthesized from guaiacol.
Vanilin is a white to slightly yellow crystals, usually needelike


Vanilin is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.
Vanilin is a phenolic aldehyde, which is an organic compound with the molecular formula C8H8O3.
Vanilin's functional groups include aldehyde, hydroxyl, and ether.


Vanilin is the primary component of the extract of the vanilla bean.
Vanilin is a phenolic aldehyde, which is an organic compound with the molecular formula C8H8O3.
Vanilin's functional groups include aldehyde, hydroxyl, and ether.


Vanilla is a flavor derived from orchids of the genus Vanilla, and has a strong vanilla and milk flavor.
Vanilin is a white to pale yellow crystal; melting 76.5 C; having 3.5 times stronger flavor and more stable in organic solvents and in storage than Vanilin but does not have the true flavor.
Vanilin is widely used in various flavored foods that need to increase the flavor of milk.



USES and APPLICATIONS of VANILIN:
Vanilin is now used more often than natural vanilla extract as a flavoring in foods, beverages, and pharmaceuticals.
The largest use of Vanilin is as a flavoring, usually in sweet foods. The ice cream and chocolate industries together comprise 75% of the market for Vanilin as a flavoring, with smaller amounts being used in confections and baked goods.


Vanilin is also used in the fragrance industry, in perfumes, and to mask unpleasant odors or tastes in medicines, livestock fodder, and cleaning products.
Vanilin is also used in the flavor industry, as a very important key note for many different flavors, especially creamy profiles such as cream soda.
Vanilin is the primary component of the extract of the vanilla bean. Synthetic Vanilin, instead of natural vanilla extract, is sometimes used as a flavouring agent in foods, beverages, and pharmaceuticals.


Vanilin is used by the food industry as well as ethylVanilin.
Artificial vanilla flavoring is a solution of pure Vanilin, usually of synthetic origin.
Because of the scarcity and expense of natural vanilla extract, there has long been interest in the synthetic preparation of its predominant component.


The first commercial synthesis of Vanilin began with the more readily available natural compound eugenol.
Today, artificial Vanilin is made from either guaiacol or from lignin, a constituent of wood which is a byproduct of the paper industry.
Vanilin is used as food flavor, daily chemical flavor, pharmaceutical intermediate, also can be used as the standard reagent for organic analysis.


Vanilin is used as a standard reagent for organic analysis
Vanilin is now used more often than natural vanilla extract as a flavoring agent in foods, beverages, and pharmaceuticals.
Vanilin is used as a food flavor, daily flavor, and pharmaceutical intermediates.


The largest use of Vanilin is as a flavoring, usually in sweet foods. The ice cream and chocolate industries together comprise 75% of the market for Vanilin as a flavoring, with smaller amounts being used in confections and baked goods.
Vanilin is also used in the flavor industry, as a very important key note for many different flavors, especially creamy profiles.


Vanilin has been used as a chemical intermediate in the production of pharmaceuticals and other fine chemicals.
The aroma, Vanilin, is stable and not volatile at high temperatures.
Vanilin is easy to oxidize in air and change color when exposed to alkaline substances.


Vanilin has vanilla bean fragrance and strong milk fragrance.
Vanilin is widely used in cosmetics, tobacco, pastries, candy and baked food industries.
Vanilin is one of the most productive synthetic fragrance varieties in the world.


The industrial production of Vanilin has a history of more than 100 years.
According to the regulations of the Ministry of Health, Vanilin can be used in larger infants, infant formula foods and infant cereals (except infant formula cereal powder), with the maximum usage of 5 mg/ml and 7 mg/100 g, respectively.


Vanilin can also be used as plant growth promoter, bactericide, lubricant defoamer, etc.
Vanilin is also an important intermediate of synthetic drugs and other spices.
In addition, Vanilin can also be used as polishing agent in electroplating industry, ripening agent in agriculture, deodorant in rubber products, anti-hardening agent in plastic products and pharmaceutical intermediates.


Vanilin is the primary component of the extract of the vanilla bean.
Synthetic Vanilin is now used more often than natural vanilla extract as a flavoring agent in foods, beverages, and pharmaceuticals.
Vanilin can be used to an important synthetic fragrance widely used in daily chemical products for food, tobacco and alcohol.


Vanilla Extract Powder is the most popular way that vanilla is used by home bakers.
Vanilla Extract Powder is produced by steeping the vanilla beans in an alcohol and water solution for several months, sometimes with sugar added, thereby producing a clear dark liquid with a rich flavor that is highly aromatic.


There are two fold and three fold extracts, called essences, but these are very strong and are mainly used by professionals.
Do not add vanilla extract powder to hot liquids as the alcohol evaporates, along with some of the vanilla flavor.
Vanilin is an edible flavoring agent.


It has a vanilla bean aroma and a strong milky aroma.
Vanilin is an indispensable and important raw material in the food additive industry.
Vanilin is soluble in hot water, glycerol and alcohol, insoluble in cold water and vegetable oil.



ANTIOXIDANT FUNCTION OF VANILIN:
The mechanism of action of antioxidants with similar structure is different.
Vanilin accelerates the scavenging of free radicals mainly by vanillic acid, an oxidation product.
Vanilin has antioxidant effect, which can significantly prolong the shelf life of oily foods and conceal their rancidity.
The isomer of Vanilin, o-Vanilin (2-hydroxy-3-methoxybenzaldehyde), has been proved to have the effect of scavenging peroxynitrite anion, but it is not a good free radical scavenger.



VANILIN, STABILIZE OTHER INGREDIENTS IN FOOD:
It has been proved that the reaction products of Vanilin can stabilize other ingredients in food: resveratrol is a natural functional component.
In order to improve its stability and give full play to its functional role, resveratrol is coated with reticular chitosan microspheres formed by the reaction of Vanilin and chitosan, which helps to control the release of resveratrol.
The condensation products of Vanilin and amino group have good ability to complex with metal ions, which can effectively improve the stability of the inclusion substances.



HISTORY OF VANILIN:
Although Vanilin is generally accepted that vanilla was domesticated in Mesoamerica and subsequently spread to the Old World in the 16th century, in 2019, researchers published a paper stating that Vanilin residue had been discovered inside jars within a tomb in Israel dating to the 2nd millennium BCE, suggesting the cultivation of an unidentified, Old World-endemic Vanilla species in Canaan since the Middle Bronze Age.
Traces of Vanilin were also found in wine jars in Jerusalem, which were used by the Judahite elite before the city was destroyed in 586 BCE.

Vanilla beans, called tlilxochitl, were discovered and cultivated as a flavoring for beverages by native Mesoamerican peoples, most famously the Totonacs of modern-day Veracruz, Mexico.
Since at least the early 15th century, the Aztecs used vanilla as a flavoring for chocolate in drinks called xocohotl.

Vanilin was first isolated as a relatively pure substance in 1858 by Théodore Nicolas Gobley, who obtained it by evaporating a vanilla extract to dryness and recrystallizing the resulting solids from hot water.
In 1874, the German scientists Ferdinand Tiemann and Wilhelm Haarmann deduced its chemical structure, at the same time finding a synthesis for Vanilin from coniferin, a glucoside of isoeugenol found in pine bark.

Tiemann and Haarmann founded a company Haarmann and Reimer (now part of Symrise) and started the first industrial production of Vanilin using their process in Holzminden, Germany.
In 1876, Karl Reimer synthesized Vanilin (2) from guaiacol (1).

By the late 19th century, semisynthetic Vanilin derived from the eugenol found in clove oil was commercially available.
Synthetic Vanilin became significantly more available in the 1930s, when production from clove oil was supplanted by production from the lignin-containing waste produced by the sulfite pulping process for preparing wood pulp for the paper industry.

By 1981, a single pulp and paper mill in Thorold, Ontario, supplied 60% of the world market for synthetic Vanilin.
However, subsequent developments in the wood pulp industry have made its lignin wastes less attractive as a raw material for Vanilin synthesis.
Today, approximately 15% of the world's production of Vanilin is still made from lignin wastes, while approximately 85% synthesized in a two-step process from the petrochemical precursors guaiacol and glyoxylic acid.

Beginning in 2000, Rhodia began marketing biosynthetic Vanilin prepared by the action of microorganisms on ferulic acid extracted from rice bran.
Vanilin is used as a flavoring agent for perfumery, cosmetics and pharmaceutical products.
Additionally, Vanilin can be used as a general-purpose stain for visualizing spots on thin-layer chromatography plates.
This stain yields a range of colors for these different components.

Vanilin–HCl staining can be used to visualize the localisation of tannins in cells.
Vanilin is becoming a popular choice for the development of bio-based plastics.
Vanilin is mostly used for flavoring foods.
The usage rate of Vanilin varies between 0.1% and 1% depending on the effect of the product and its interaction with other substances.



ARE VANILIN AND VANILLA THE SAME THING?
Even though Vanilin and vanilla are used for the same purpose, they are not the same product.
Vanilla is a natural aroma obtained from plants.
On the contrary, Vanilin is a chemically structured product.

Only 2% of Vanilin comes from vanilla.
Vanilin is a flavoring substance produced by the vanilla beetle.
Naturally, the Vanilin produced by the vanilla beetle is of higher quality than other Vanilin substances in terms of taste and aroma.

Vanilin is used as a variety of sweeteners in foods, beverages, perfumes, cosmetics and other products.
Vanilin is also used in pharmaceutical products.
The key difference between Vanilin and pure Vanilin is that pure Vanilin is produced naturally while Vanilin is usually produced synthetically.

Pure Vanilin contains vanilla beetle bean produced by the vanilla beetle, so it provides a higher quality aroma and taste.
Vanilin, on the other hand, is produced synthetically, usually without vanilla beetle bean, and provides a less high-quality aroma and taste.
Pure Vanilin is more expensive because it is harder to produce and much less efficient.



β-d-GLUCOSIDE OF VANILIN:
After being harvested, their flavor is developed by a months-long curing process, the details of which vary among vanilla-producing regions, but in broad terms Vanilin proceeds as follows:

First, the seed pods are blanched in hot water, to arrest the processes of the living plant tissues.
Then, for 1–2 weeks, the pods are alternately sunned and sweated: during the day they are laid out in the sun, and each night wrapped in cloth and packed in airtight boxes to sweat.

During this process, the pods become dark brown, and enzymes in the pod release Vanilin as the free molecule.
Finally, the pods are dried and further aged for several months, during which time their flavors further develop.
Several methods have been described for curing vanilla in days rather than months, although they have not been widely developed in the natural vanilla industry, with its focus on producing a premium product by established methods, rather than on innovations that might alter the product's flavor profile.



BIOSYNTHESIS OF VANILIN:
Although the exact route of Vanilin biosynthesis in V. planifolia is currently unknown, several pathways are proposed for its biosynthesis.
Vanilin biosynthesis is generally agreed to be part of the phenylpropanoid pathway starting with l-phenylalanine, which is deaminated by phenylalanine ammonia lyase (PAL) to form t-cinnamic acid.

The para position of the ring is then hydroxylated by the cytochrome P450 enzyme cinnamate 4-hydroxylase (C4H/P450) to create p-coumaric acid.
Then, in the proposed ferulate pathway, 4-hydroxycinnamoyl-CoA ligase (4CL) attaches p-coumaric acid to coenzyme A (CoA) to create p-coumaroyl CoA.
Hydroxycinnamoyl transferase (HCT) then converts p-coumaroyl CoA to 4-coumaroyl shikimate/quinate.

This subsequently undergoes oxidation by the P450 enzyme coumaroyl ester 3’-hydroxylase (C3’H/P450) to give caffeoyl shikimate/quinate.
HCT then exchanges the shikimate/quinate for CoA to create caffeoyl CoA, and 4CL removes CoA to afford caffeic acid.
Caffeic acid then undergoes methylation by caffeic acid O-methyltransferase (COMT) to give ferulic acid.

Finally, Vanilin synthase hydratase/lyase (vp/VAN) catalyzes hydration of the double bond in ferulic acid followed by a retro-aldol elimination to afford Vanilin.
Vanilin can also be produced from vanilla glycoside with the additional final step of deglycosylation.

In the past p-hydroxybenzaldehyde was speculated to be a precursor for Vanilin biosynthesis.
However, a 2014 study using radiolabelled precursor indicated that p-hydroxybenzaldehyde is not used to synthesise Vanilin or Vanilin glucoside in the vanilla orchids.



CHEMICAL SYNTHESIS OF VANILIN:
The demand for vanilla flavoring has long exceeded the supply of vanilla beans.
As of 2001, the annual demand for Vanilin was 12,000 tons, but only 1,800 tons of natural Vanilin were produced.
The remainder was produced by chemical synthesis.

Vanilin was first synthesized from eugenol (found in oil of clove) in 1874–75, less than 20 years after it was first identified and isolated. Vanilin was commercially produced from eugenol until the 1920s.
Later it was synthesized from lignin-containing "brown liquor", a byproduct of the sulfite process for making wood pulp.

Counterintuitively, though it uses waste materials, the lignin process is no longer popular because of environmental concerns, and today most Vanilin is produced from the petrochemical raw material guaiacol.
Several routes exist for synthesizing Vanilin from guaiacol.

At present, the most significant of these is the two-step process practiced by Rhodia since the 1970s, in which guaiacol (1) reacts with glyoxylic acid by electrophilic aromatic substitution.
The resulting vanillylmandelic acid (2) is then converted by 4-Hydroxy-3-methoxyphenylglyoxylic acid (3) to Vanilin (4) by oxidative decarboxylation.



WOOD-BASED VANILIN:
15% of the world's production of Vanilin is produced from lignosulfonates, a byproduct from the manufacture of cellulose via the sulfite process.
The sole producer of wood-based Vanilin is the company Borregaard located in Sarpsborg, Norway.
Wood-based Vanilin is produced by copper-catalyzed oxidation of the lignin structures in lignosulfonates under alkaline conditions and is claimed by the manufacturing company to be preferred by their customers due to, among other reasons, its much lower carbon footprint than petrochemically synthesized Vanilin.



FERMENTATION OF VANILIN:
The company Evolva has developed a genetically modified microorganism which can produce Vanilin.
Because the microbe is a processing aid, the resulting Vanilin would not fall under U.S. GMO labeling requirements, and because the production is nonpetrochemical, food using the ingredient can claim to contain "no artificial ingredients".
Using ferulic acid as an input and a specific non GMO species of Amycolatopsis bacteria, natural Vanilin can be produced.



BIOCHEMISTRY OF VANILIN:
Several studies have suggested that Vanilin can affect the performance of antibiotics in laboratory conditions.



MANUFACTURING OF VANILIN:
Vanilin has been used as a chemical intermediate in the production of pharmaceuticals, cosmetics, and other fine chemicals.
In 1970, more than half the world's Vanilin production was used in the synthesis of other chemicals.
As of 2016, Vanilin uses have expanded to include perfumes, flavoring and aromatic masking in medicines, various consumer and cleaning products, and livestock foods.



ANTIBACTERIAL ACTIVITY OF VANILIN:
VanilinCAS 121-33-5 is a kind of natural bacteriostatic agent.
Vanilin is often combined with other bacteriostatic methods in the field of food.
Vanilin has different bacteriostatic effects on different strains of bacteria.

The bacteriostatic effect of Vanilin is related to its concentration and pH value.
Higher Vanilin concentration and lower pH value are beneficial to improve the bacteriostatic effect of Vanilin.
Vanilin has different bacteriostatic effect on different strains. Compared with other strains, Vanilin has better bacteriostatic effect on Escherichia coli.

Vanilin can inhibit many kinds of yeasts.
High concentration of Vanilin can improve its bacteriostatic effect, but high concentration of Vanilin can not kill yeasts immediately.
Compound preservation achieves synergistic effect between preservatives (or preservation methods).

Vanilin CAS 121-33-5 is a widely accepted preservation method for fruits and vegetables.
The antimicrobial effect of spices is often synergistic and the dosage is smaller than that of single use.
For example, for the prevention of Aspergillus Niger pollution, the effective sterilization dose of Vanilin alone is 0.5%.

The mixture of 0.05% Vanilin and 0.0025% cinnamaldehyde can play a bactericidal role.
Vanilin also plays an important role in assisting bacteriostasis and sterilization.

In the current production process, thermal sterilization is still the most common way of sterilization in juice processing, which is generally pasteurization and instantaneous sterilization at high temperature.
Traditional sterilization methods often lead to the destruction of nutrients and browning of fruit juice.



PHYSICAL and CHEMICAL PROPERTIES of VANILIN:
Chemical formula: C8H8O3
Molar mass: 152.149 g•mol−1
Appearance: White crystals
Odor: Vanilla, sweet, balsamic, pleasant
Density: 1.056 g/cm3
Melting point: 81 °C (178 °F; 354 K)
Boiling point: 285 °C (545 °F; 558 K)
Solubility in water: 10 g/L
log P: 1.208
Vapor pressure: >1 Pa
Acidity (pKa): 7.781
Basicity (pKb): 6.216
Structure:
Crystal structure: Monoclinic
Thermochemistry:
Std enthalpy of combustion (ΔcH⦵298): −3.828 MJ/mol

Synonyms: 4-hydroxy-3-methoxybenzaldehyde
IUPAC Name: 4-hydroxy-3-methoxybenzaldehyde
Molecular Weight: 152.15
Molecular Formula: C8H8O3
Canonical SMILES: COC1=C(C=CC(=C1)C=O)O
InChI: InChI=1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3
InChIKey: MWOOGOJBHIARFG-UHFFFAOYSA-N
Boiling Point: 170 °C at 15 mmHg
Melting Point: 81-83 °C
Flash Point: 147ºC
Purity: > 98%
Density: 1.06 g/cm3
Solubility: Soluble in chloroform (slightly), ethyl acetate (slightly), methanol (slightly).

Appearance: White to pale yellow crystalline or powder
Storage Keep container tightly closed in a dry and well-ventilated place.
EINECS: 204-465-2
Hazard Codes: Xn
HS Code: 2912410000
Log P: 1.21330
MDL: MFCD00006942
pH: Solutions are acid to litmus
PSA: 46.53
Quality Standard: Enterprise Standard
Refractive Index: 1.555
Risk Statements: R22
RTECS: YW5775000
Safety Statements: S22-S24/25
Stability: Stable.
May discolour on exposure to light.
Moisture-sensitive.

Incompatible with strong oxidizing agents, perchloric acid.
Vapor Pressure: 1 mmHg at 225 °F
Molecular Weight: 152.15 g/mol
XLogP3: 1.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 2
Exact Mass: 152.047344113 g/mol
Monoisotopic Mass: 152.047344113 g/mol
Topological Polar Surface Area: 46.5Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 135
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Beilstein Number: 0472792
MDL: MFCD00006942
CoE Number: 107
XlogP3: 1.20 (est)
Molecular Weight: 152.14936000
Formula: C8 H8 O3
Appearance: white to off white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Melting Point: 81.00 to 84.00 °C. @ 760.00 mm Hg
Boiling Point: 285.00 to 286.00 °C. @ 760.00 mm Hg
Boiling Point: 170.00 to 171.00 °C. @ 15.00 mm Hg
Vapor Pressure: 0.002000 mmHg @ 25.00 °C. (est)
Vapor Density: 5.3 ( Air = 1 )
Flash Point: 307.00 °F. TCC ( 153.00 °C. )
logP (o/w): 1.210
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.

Soluble in:
chloroform
dipropylene glycol
ether
ethyl alcohol, 1:2 in 95% alcohol
ethyl alcohol, 1:3 in 70% alcohol
ethyl alcohol, 4 parts in 50% alcohol
glycerol
glycerol, 1:20
hot ligroin
isopropyl myristate
water, 1:125 in water
water, 1gm in 100ml
water, 6875 mg/L @ 25 °C (est)
Insoluble in:
paraffin oil
Stability:
cream
hair spray
lotion
powder

CAS number: 121-33-5
EC number: 204-465-2
Grade: Ph Eur,BP,NF
Hill Formula: C₈H₈O₃
Chemical formula: (CH₃O)(OH)C₆H₃CHO
Molar Mass: 152.15 g/mol
HS Code: 2912 41 00
Density: 1.06 g/cm3 (20 °C)
Flash point: 159.8 - 160.8 °C
Ignition temperature: >400 °C
Melting Point: 81 - 83 °C
pH value: 4.3 (10 g/l, H₂O, 20 °C)
Vapor pressure: 0.0029 hPa (25 °C)
Bulk density: 600 kg/m3
Solubility: 9 g/l
Molecular Formula / Molecular Weight: C8H8O3 = 152.15

Physical State (20 deg.C): Solid
Store Under Inert Gas: Store under inert gas
Condition to Avoid: Light Sensitive,Air Sensitive,Moisture Sensitive
CAS RN: 121-33-5
Reaxys Registry Number: 472792
PubChem Substance ID: 87570691
SDBS (AIST Spectral DB): 726
Merck Index (14): 9932
MDL Number: MFCD00006942
Physical state: crystalline, powder
Color: light yellow
Odor: characteristic
Melting point/freezing point:
Melting point/range: 81 - 83 °C - lit.
Initial boiling point and boiling range: 170 °C at 20 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 159,8 - 160,8 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 4,3 at 10 g/l at 20 °C

Viscosity
Viscosity, kinematic: Not applicable
Viscosity, dynamic: Not applicable
Water solubility: 9 g/l at 25 °C
Partition coefficient: n-octanol/water:
log Pow: 1,21 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: < 0,01 hPa at 25 °C
Density: 1,056 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Relative vapor density: 5,3 at 25 °C
CAS: 121-33-5
EINECS: 204-465-2
InChI: InChI:1S/C8H8O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-5,10H,1H3
Molecular Formula: C8H8O3
Molar Mass: 152.15

Density: 1.06
Melting Point: 81-83°C(lit.)
Boling Point: 170°C15mm Hg(lit.)
Flash Point: 147 °C
JECFA Number: 889
Water Solubility: 10 g/L (25 ºC)
Solubility: Soluble in 125 times water, 20 times ethylene glycol and 2 times 95% ethanol, soluble in chloroform.
Vapor Presure: >0.01 mm Hg ( 25 °C)
Vapor Density: 5.3 (vs air)
Appearance: White needle crystal.
Color: White to pale yellow
Merck: 14,9932
BRN: 472792
pKa: pKa 7.396±0.004(H2OI = 0.00t = 25.0±1.0) (Reliable)
PH: 4.3 (10g/l, H2O, 20℃)
Storage Condition: 2-8°C
Stability: Stable.
May discolour on exposure to light.
Moisture-sensitive.
Incompatible with strong oxidizing agents, perchloric acid.

Sensitive: Air & Light Sensitive
Refractive Index: 1.4850 (estimate)
MDL: MFCD00006942
Chemical Name: Vanilin
CAS Registry Number: 121-33-5
PubChemID: 1183
Molecular Weight: 152.14732
PSA: 46.53000
LogP: 1.21330
EINECS: 204-465-2
Molecular Formula: C8H8O3
Density: 1.06
Boiling Point: 170℃ (15 mmHg)
Flash Point: 147℃
Melting Point: 81-84℃
Vapour: 0.00194mmHg at 25°C
Refractive Index: 1.555
HS Code: 29124100



FIRST AID MEASURES of VANILIN:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person. Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of VANILIN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of VANILIN:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of VANILIN:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of VANILIN:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Air, light, and moisture sensitive.



STABILITY and REACTIVITY of VANILIN:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .






VANILLIC ACID
SYNONYMS 4-Hydroxy-3-methoxybenzaldehyde; 3-Methoxy-4-hydroxybenzaldehyde; p-Hydroxy-m-methoxybenzaldehyde; Vanillic aldehyde; 2-Methoxy-4-formylphenol; 4-Formyl-2-methoxyphenol; 4-Hydroxy-5-methoxybenzaldehyde; Vanilla; 4-Hydroxy-m-anisaldehyde; Methyl protocatechualdehyde; p-Vanillin; 4-Hydroxy-m-anisaldehyde; Vanillaldehyde; m-Methoxy-p-hydroxybenzaldehyde; Protocatechualdehyde 3-methyl ether; 2-Methoxy-4-formylphenol;CAS NO. 121-33-5; 52447-63-9; 8014-42-4
VANILLIN
Vanilline; VANILLIN, N° CAS : 121-33-5 - Vanilline, Origine(s) : Végétale, Synthétique, Autres langues : Vaniglia, Vanilina, vanilin, Nom INCI : VANILLIN, Nom chimique : Vanillin. N° EINECS/ELINCS : 204-465-2. Compatible Bio (Référentiel COSMOS) : Ses fonctions (INCI): Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Noms français : 2-METHOXY-4-FORMYLPHENOL; 3-METHOXY-4-HYDROXYBENZALDEHYDE; 4-FORMYL-2-METHOXYPHENOL; 4-HYDROXY-3-METHOXY BENZALDEHYDE; 4-HYDROXY-3-METHOXYBENZALDEHYDE; 4-HYDROXY-5-METHOXYBENZALDEHYDE; 4-HYDROXY-M-ANISALDEHYDE; BENZALDEHYDE, 4-HYDROXY-3-METHOXY-; HYDROXY-4 METHOXY-3 BENZALDEHYDE;M-ANISALDEHYDE, 4-HYDROXY M-ANISALDEHYDE, 4-HYDROXY-; METHYLPROTOCATECHUIC ALDEHYDE; P-HYDROXY-M-METHOXYBENZALDEHYDE; PROTOCATECHUALDEHYDE 3-METHYL ETHER; PROTOCATECHUALDEHYDE, METHYL-; Vanilline. Utilisation et sources d'émission: Agent de saveur; Vanillin. CAS names : Benzaldehyde, 4-hydroxy-3-methoxy-; IUPAC names: 1-butoxypropan-2-ol; 3-hydroxy-4-methoxybenzaldehyde; 3-Methoxy-4-hydroxy benzaldehyde; 4-hydroksy-3-metoksybenzaldehyd, ; 4-Hydroxy-3-methoxy-benzaldehyde; 4-Hydroxy-3-methoxybenzaldehyd; 4-Hydroxy-3-methoxybenzaldehyde; 4-Hydroxy-3-methoxybenzaldehyde, Vanillic aldehyde; 4-hydroxy-3-méthoxybenzaldéhyde; Ester; vanilin; vanilla; Vanillin (4-hydroxy-3-methoxybenzaldehyde); wanilina; 121-33-5 [RN], vanilya; 204-465-2 [EINECS]; 2-Methoxy-4-formylphenol ; 3-methoxy-4-hydroxybenzaldehyde; 4-08-00-01763 [Beilstein]; 472792 [Beilstein]; 4-formyl-2-methoxyphenol; 4-Hydroxy-3-methoxybenzaldehyd [German] [ACD/IUPAC Name] ; 4-hydroxy-3-methoxy-benzaldehyde; 4-Hydroxy-3-methoxybenzaldehyde [ACD/IUPAC Name]; 4-Hydroxy-3-méthoxybenzaldéhyde [French] [ACD/IUPAC Name]; 4-Hydroxy-5-methoxybenzaldehyde 4-hydroxy-m-anisaldehyde; Benzaldehyde, 4-hydroxy-3-methoxy- [ACD/Index Name]; m-Anisaldehyde, 4-hydroxy-; MFCD00006942 [MDL number]; p-hydroxy-m-methoxybenzaldehyde ; Vanilin [Turkish]; Vanilina [Portuguese]; Vanilina [Spanish]; Vanillic aldehyde; Vanillin; Vanillin [German]; Vanillin Melting Point Standard; Vanillina [Italian]; Vanilline [French]; Βανιλίνη [Modern Greek (1453-)]; Ванилин [Russian]; バニリン [Japanese]; 香草醛 [Chinese]; 4-hydroxy 3-methoxybenzaldehyde; Acetovanillone; apocynine; Lioxin; m-Methoxy-p-hydroxybenzaldehyde; para-Hydroxy-meta-methoxybenzaldehyde; p-vanillin; Vanilin; vaniline; Vanilla; vanillaldehyde; Vanillin|4-Hydroxy-3-methoxybenzaldehyde; VHR DQ CO1 [WLN]; Zimco
VANTOCIL IB
VANTOCIL IB VANTOCIL IB Antimicrobial VANTOCIL IB Antimicrobial is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers. This product is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB). VANTOCIL IB Antimicrobial is produced for use in industrial, institutional, agricultural, food, beverage, and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants. Vantocil Product Overview Vantocil IB and Vantocil TG are aqueous solutions of the powerful antibacterial preservative poly(hexamethylene biguanide) hydrochloride [PHMB], an active offering broad pH tolerance, low foam and good heat stability. Applications are varied, and include surface care, fabric care and automotive care. PROPERTIES Vantocil IB and Vantocil TG are aqueous solutions of the powerful antibacterial preservative poly(hexamethylene biguanide) hydrochloride [PHMB], an active offering broad pH tolerance, low foam and good heat stability. Applications are varied, and include surface care, fabric care and automotive care. Vantocil IB Antimicrobial is a broad spectrum, fast acting bactericide for disinfectants and sanitizers in industrial, institutional, agricultural, food, beverage and domestic disinfection applications. It is effective in a wide range of industrial disinfection applications, primarily as a solid surface dispersant. Application areas include hospitals, institutions, veterinary establishments, dairies, milking parlors, and other food processing plants. VANTOCIL IB has been shown to be very effective against Mycobacterium smegmatis and Mycobacterium intracellularis responsible for tuberculosis in pigs. VANTOCIL IB has also been shown to be effective at eradicating Salmonella pullorum, Salmonella typhimurium, Heamophilus gallinarum, Mycoplasma synoviae and pathogenic E.coli, which are responsible for white diarrhoea, respiratory disease and colibacillosis in chickens. Features VANTOCIL IB is based on Arch's highly active biocide poly(hexamethylene biguanide) hydrochloride, also known as PHMB. •Fast acting bactericide, effective at low concentrations •Extensive toxicity studies suggest acceptable use •Retains activity in the presence of organic matter such as •Active against enveloped RNA, enveloped DNA, naked •Readily dilutable in hot and cold water •Provides stable formulations with both acids and alkalis •Low corrosion, and compatible with common materials of •Active in both soft and hard water •Effective and stable over a pH range of 1 - 11 VANTOCIL IB is a highly effective, fast-acting biocide for the formulation of disinfectants and sanitizers, and is a 20%aqueous solution of poly(hexamethylene biguanide) hydrochloride, also known as PHMB. VANTOCIL FHC is anaqueous formulation of PHMB and quaternary ammonium compound. PARA-GENE Poly BiQuinide Disinfectant Vantocil IB concentrate formula isdesigned for use as a powerful surface and terminal non-tainting sanitiser which has a broad spectrum of activity against micro-organisms. VANTOCIL IB is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitizers, for use in industrial, institutional, agricultural, food, beverage and domestic disinfection applications. VANTOCIL IB is a 20% aqueous solution of poly(hexamethylene biguanide) hydrochloride also known as PHMB. Poly (hexamethylene biguanide)hydrochloride (PHMB),Vantocıl IB, An effective preservative for formulations containing non-ionic or cationic ingredients, such as PVA & VAEemulsion polymers, silicone emulsions, PVA & starch based adhesives, and certain types of rheology modifiers Rapid, non-formaldehdye mechanism. Vantocil IB by Lonza is an aqueous solution. It is highly effective preservative for use in a wide variety of applications including oil-inwater and water-in-oil emulsions, industrial reagents, silicone systems, cellulose solutions and oil recovery systems. Can also be used to preserve aqueous based adhesives (such as animal glues, latex adhesives based on polyvinyl acetate, PVA, starch, dextrin, casein and other glues, and latex adhesives intended for food packaging applications). Recommended usage level of Vantocil IB is 500-5000 ppm. This product can be used alone or in combination with other biocides to create products for a wide range of disinfection applications. It is a broad-spectrum, fast-acting bactericide that can be used in various formulations for disinfectants and sanitizers. The Vantocil IB product can be used for industrial, institutional, agricultural, food and beverage, and pool and spa water treatment applications as well as domestic disinfection applications. This product is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride, also known as PHMB. The combination of the different modes of biocidal action reduces the risk of bacterial resistance, and the product is effective in a wide range of industrial disinfection applications. Disinfection by fumigation or fogging is commonly practiced in areas, which require a high degree of hygiene control. This disinfection encompasses control of microorganisms in air as well as on surface. The process of disinfection involves the use of antimicrobial chemicals or biocides to kill viable microorganisms. In the present study, the efficacy of biocide Vantocil-IB as an aerial and surface disinfectant was determined. Solution of Vantocil-IB was fogged in to a room with help of mechanical fogger and the aerial and surface microbial load was determined before and after fogging. Vantocil-IB at 0.2 gm% concentration showed significant reduction in the number of viable microorganisms in air and on the surface of the room. A contact time of 1hour and a fogging time of 20-25 minutes proved effective in reducing the number of microorganisms to safe level. Study of a biocide [Vantocil-IB] for aerial and surface disinfection. Immersion of freshly processed poultry carcasses in solutions of poly(hexamethylenebiguanide hydrochloride), PHMB,VANTOCIL IB, retarded bacterial growth and markedly improved the shelf-life during storage at 2 C.Birds treated with 200, 300, and 400 ppm PHMB had average shelf-livesof 22.9, 25.9, and 26.0 days, respectively, compared to the 10.5 days ofshelf-life for water-treated controls. Duncan's multiple range testrevealed that the shelf-life differences among PHMB-treated birds were not statistically significant. VANTOCIL IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride, also known as PHMB. The combination of the different modes of biocidal action reduces the risk of bacterial resistance, and the products are effective in a wide range of industrial disinfection applications. The levels of VANTOCIL IB Antimicrobial to prevent thegrowth of problem micro-organisms are listed in Table 1.MICs do not represent effective use levels but do indicatethe intrinsic broad spectrum of activity of VANTOCIL IB Antimicrobial.VANTOCIL IB Antimicrobial has a non-specific mode ofbiocidal action which means that bacterial resistance is veryunlikely to occur. Detailed information on the mode ofaction of VANTOCIL IB Antimicrobial is available onrequest. VANTOCIL IB Antimicrobial can be used alone or incombination with other biocides to create products for awide range of disinfection applications. Considerable data exists which provides a measure of theintrinsic anti-microbial activity of VANTOCIL IBAntimicrobial, generated via European suspension testprotocols relevant to application in Food, Industrial,Domestic and Institutional Hygiene.Its activity has been further demonstrated under conditionsrepresentative of practical use, and a range of useconcentrations is provided in Table 3. However, it isrecommended that field tests under practical conditions beundertaken to determine the most cost-effective dose foryour application.This data and information on the compatibility of VANTOCIL IB Antimicrobial with a range of formulating chemicals is available on request. VANTOCIL IB is a liquid antimicrobial agent. Used in conjunction with Proxel GXL to prevent bacterial attack during brine curing; and for short term preservation of fresh hides. As a quick kill bactericide Vantocil quickly lowers the bacterial count in the raceway and on the hides, and results in a more bacteria free hide which then can be treated with a longer term bactericide such as Proxel GXL. Vantocil ib polymeric biguanide; a preservative for coatings raw materials including silicone emulsions, polyvinyl alcohol and polyvinyl acetate; quick kill, broad spectrum antimicrobial activity; pale yellow liquid; odorless. The polychaete Platynereis dumerilii (Polychaeta: Nereidae) has been evaluated as a candidate bioassay species for marine ecotoxicity testing. The species conforms with many of the requirements of an ideal bioassay organism in that (i) it is amenable to laboratory culture, (ii) its relatively small size makes it convenient for handling and laboratory exposure studies, (iii) its diet is defined and can be controlled, (iv) it reproduces throughout the year and, using photoperiod manipulation, can be induced to spawn as required, and (v) it has a short life cycle (approximately 3 months at 20°C) making it feasible to study the effects of xenobiotics on chronic endpoints such as reproduction. The components of the life history which have been examined to date include fertilization rate, embryo-larval development, and larval survival. These life stages were evaluated using the reference materials used in the 1991 International Paris Commission (PARCOM) Ring Test (namely, the biocides, Bioban P-1487 and Vantocil IB, and the widely used reference toxicant, 3,5-dichlorophenol). For fertilization rate, the median effect concentrations (1-h EC50 values) were 0.32 mg · liter−1 for Bioban P-1487, 1.99 mg · liter−1 for 3,5-dichlorophenol, and 9.66 mg · liter−1 for Vantocil IB. For embryo-larval development, the median effect concentrations (48-h EC50 values) were 0.29 mg · liter−1 for Bioban P-1487, 2.13 mg · liter−1 for 3,5-dichlorophenol, and 4.81 mg · liter−1 for Vantocil IB. For larval survival, the median lethal concentrations (48-h LC50 values) were 0.32 mg · liter−1 for Bioban P-1487, 3.64 mg · liter−1 for 3,5-dichlorophenol, and 10.9 mg · liter−1 for Vantocil IB. These results (all based on nominal values) suggest that, for these reference materials, the early life stages of P. dumerilii are of similar sensitivity to other marine invertebrate species. Together with the amenability of this species to laboratory culture, these data suggest that P. dumerilii has significant potential for use in marine ecotoxicity testing. PHMB (Vantocil) acts as disinfectant and preservative. It typically exhibits goodbactericidal activity but slower fungicidal and acanthamoebicide activity and provides long term storage capability for the lens. The usual disinfection time is 4-6 hours. The multipurpose solution containing Polyhexanide or PHMB (Vantocil) meets FDA and ISO primary standards. The effects of chlorhexidine diacetate and vantocil IB on the viability of Providencia stuartii strains are described. Exposure of Prov. stuartii strains to different concentrations of chlorhexidine in broth culture resulted in a decrease in viability over the first 6 h, followed by regrowth. During incubation, bacteria adhered to the surface of the culture vessel and multiplied despite the presence of a bactericidal concentration of the drug in the medium. It is concluded that the phenomenon of ‘regrowth’ results from adhesion to glass containers and the subsequent dispersal of some of these cells into the culture medium. With the objective of characterizing the occurrence of red leg in Minas Gerais, young and adult frogs with foot and finger ulcers, hemorrhagic effusion on the skin of the ventral region, motor incoordination, high mortality rates in adults and abscesses to necropsy. In the culture of fragments of damaged skin and abscesses, Aeromonas hydrophila was isolated and identified . The bactericidal effect of VANTOCIL IB was higher than potassium permanganate, determined by the minimum inhibitory concentration for isolated colonies. The actions of chlorhexidine, cetrimide and Vantocil (the hydrochloride of a polymeric biguanide) on bacteria and spheroplasts or protoplasts derived therefrom have been compared. Lysis of Escherichia coli spheroplasts by chlorhexidine or cetrimide is due to rupture of the cytoplasmic membrane. Membranes ruptured with cetrimide can reform to give small, empty envelopes. With increasing concentrations of cetrimide or chlorhexidine more and more granules appear in the cytoplasm, increasing in size with increasing concentration, until the structure becomes transformed to a granular body similar in size to the original spheroplast. With chlorhexidine or Vantocil this now electron‐dense body is rigid, but with cetrimide it collapses to a flat disc which does not lyse. The granules appear to consist of coagulated cytoplasm. This effect of excess of these antiseptics not only prevents osmotic lysis of the spheroplast or the collapsed disc but renders them immune to lysis by a variety of chemical agents. In isolated cytoplasm, chlorhexidine or cetrimide causes precipitation over a narrow range of concentrations but greater than those required for lysis. With Vantocil precipitation occurs gradually over a wide range of concentrations, starting at concentrations equal to those which cause a limited amount of lysis of the spheroplast or a relatively small increase in permeability of intact bacteria. Lanthanous and uranyl ions also precipitate cell contents but do not lyse spheroplasts; spheroplasts treated with these ions are protected from lysis by other agents. VANTOCIL IB Antimicrobial is a bactericide manufactured by Excel Industries Limited. PROPERTIES: VANTOCIL IB is a broad spectrum, fast acting bactericide for the formulation disinfectants and sanitisers, for use in industrial, institution , agriculture, food beverage and domestic disinfection applications. VANTOCIL IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrocloride, also known as PHMB. Composition: An aqueous solution of PHMB. Physical form: It is a slighty opalesscent colorless to pale yellow liquid of pH 4.0-4.5 and density (at 25øC) 1.14 Application: VANTOCIL IB is effective in a wide range of industrial disinfection applications , primarily as a solid surface disinfectant. application areas include: ? Hospitals ? Institutions ?Veterynary Establishment ? Dairies ? Milking parlours ? Poultry hatcheries ? Food processing plants ? Breweries ? Pasteurisers in canned food & beverage bottling plants ? Yoghurt fermentation ? Air-Conditioning units ? Cheese moulds ? Beer glass cleaner VANTOCIL IB Antimicrobial manufacturer is Excel Industries Limited but there can be plenty of supplier for supplying or exporting of VANTOCIL IB Antimicrobial substitute or equivalent. Such substitute chemicals are usually of same chemistry types and can benefit the user in economical aspects. APPLICATIONS •Hospitals •Institutions •Veterinary establishments •Diaries •Milking parlors •Poultry hatcheries •Food processing plants •Breweries •Pasteurizes in canned food & beverage bottling plants •Yoghurt fermentation •Air-conditioning units •Cheese molds •Beer glass cleaners BENEFITS: • Rapid bactericidal action, in low concentrations, effective against gram positive and negative bacteria. In higher dosage, effective against fungi and yeasts; • Low toxicity to humans; • Maintains activity in the presence of organic matter; • Low foam, suitable for CIP systems and pasteurization processes; • Soluble in hot or cold water; • Active against viruses; • Compatible with acid formulations or alkaline detergents; • Low corrosivity, and can be used on surfaces of different materials; • Stable in the presence of hard water and high temperatures; • Stable and effective in the pH range from 1 to 11. The active ingredient, PHMB, is thermally stable and non-volatile, with bactericidal, virucidal and fungicidal activity. It does not leave spots on the surfaces, it has low formation of foam, of easy rinsing, besides not changing the organoleptic properties
VANTOCIL P
Vantocil P is best known for its broad-spectrum antimicrobial and antifungal activity.
Vantocil P is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu (Bauch & Lomb, Rochester, NY).
Vantocil P is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.

CAS Number: 32289-58-0
Molecular Formula: C10H23N5
Molecular Weight: 213.32312
EINECS Number: 1308068-626-2

32289-58-0, N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide, SCHEMBL24018755, Polyhexamethylene Biguanidine HCl, BCP13780, AKOS015919499, N-(6-(3-Methylguanidino)hexyl)acetimidamide, 1824322-57-7, Poly(iminoimidocarbonyliminoimidocarbonyliminohexamethylene) hydrochloride, Vantocil IB, Vantocil TG,
Poly(iminoimidocarbonyliminoimidocarbonylimino hexamethylene monohydrochloride), Guanidine,Poly(hexamethylene Diguanide)
Hydrochloride,Poly(hexamethylenebicyanoguanide-Hexamethylenediamine) Hydrochloride, Reputex20, Vantocil 100, Vantocil Ib, Vantocil P, Vantocil Tg, A-Breeze, Baquacil, Baquacil Ultra, Caswell No. 676, Chlorhexidine complex, Cosmoquil QC, PHMB, Polyhexanide, Vantocil 1B, Vantocil P (20% w/w polihexanide), Baquacil, Clorhidrato de poli(imino imido) biguanidina, Cosmoquil CQ, Vantocil 1B, Vandocil P, Baquacil, cosmocil, Lavasept, PHMB polymer, polihexanide, polihexanidehydrochloride, poly(hexamethylene biguanide), poly(hexamethylenebiguanide) hydrochloride, polyhexamethylenbiguanide, polyhexamethylenbiguanid,
polyhexamethylenbiguanide ,polyhexamethylene biguanide, Vantocil P,polyhexanide,Vantocil,Vantocil IB of Vantocil

Vantocil P Antimicrobial is a broad spectrum, fast acting antimicrobial for the formulation of disinfectants and sanitizers for use in commercial, industrial, and domestic disinfection applications.
Vantocil P may be used to formulate sanitizers and disinfectants for use in food handling and storage establishments, premises, and equipment.
Vantocil P is a chemical compound that belongs to the biguanide class of chemicals.

Vantocil P is a polymer, meaning it is made up of repeating units of smaller molecules.
Vantocil P is known for its antimicrobial properties, which make it effective against a broad spectrum of microorganisms, including bacteria, fungi, and some viruses.
Vantocil P and Vantocil TG are aqueous solutions of the powerful antibacterial preservative poly(hexamethylene biguanide) hydrochloride [PHMB], an active offering broad pH tolerance, low foam and good heat stability.

Vantocil P applications are varied, and include surface care, fabric care and automotive care.
Vantocil P is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.
Vantocil P may be used to formulate sanitizers and disinfectants for use in food handling/storage establishments, premises and equipment, including food contact surfaces in public eating places, dairy processing equipment, and food processing equipment and utensils.

Vantocil P is best known for its broad-spectrum antimicrobial and antifungal activity.
Vantocil P is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu (Bauch & Lomb, Rochester, NY).

Vantocil P is a polymer used as a disinfectant and antiseptic.
In dermatological use,Vantocil P is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide.
Vantocil P has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.

Vantocil Ps are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.
Vantocil P eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Vantocil P is an antiseptic with antiviral and antibacterial properties used in a variety of products including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners.

Vantocil P is a cationic polymer with antimicrobial and antiviral properties.
Vantocil P Antimicrobial is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.
Vantocil P is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB).

Vantocil P Antimicrobial is produced for use in industrial, institutional, agricultural, food, beverage, and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants.
Vantocil P is a new environment-friendly cationic water-soluble polymer.
Vantocil P is a water solution that can be used as a broad spectrum and high efficient disinfectant.

Vantocil P is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of its special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.
Vantocil P is often used in products such as hand sanitizers, antiseptic creams, wound care products, and contact lens solutions for its antimicrobial and preservative properties.

Vantocil P can be used in textiles to impart antimicrobial properties, helping to prevent the growth of bacteria and fungi on fabrics.
Vantocil P is used in swimming pools and hot tubs as a disinfectant to control microbial growth in the water.
Some medical devices and equipment may be treated with Vantocil P to reduce the risk of microbial contamination.

Vantocil P is a cationic polymer with antimicrobial and antiviral properties.
Vantocil P has been commonly accepted that the antimicrobial activity is due to the ability of Vantocil P to perforate the bacterial phospholipid membrane leading ultimately to its death.
Vantocil P is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.

Vantocil P has been commonly accepted that the antimicrobial activity is due to the ability of Vantocil P to perforate the bacterial phospholipid membrane leading ultimately to its death.
Vantocil P is a new environment-friendly cationic water-soluble polymer.
Vantocil P is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.

Because of its special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.
Vantocil P and Vantocil TG are aqueous solutions of the powerful antibacterial preservative poly(hexamethylene biguanide) hydrochloride [PHMB], an active offering broad pH tolerance, low foam and good heat stability.
Applications are varied, and include surface care, fabric care and automotive care.

Vantocil P Antimicrobial is a broad spectrum, fast acting bactericide for disinfectants and sanitizers in industrial, institutional, agricultural, food, beverage and domestic disinfection applications.
Vantocil P is effective in a wide range of industrial disinfection applications, primarily as a solid surface dispersant.
Application areas include hospitals, institutions, veterinary establishments, dairies, milking parlors, and other food processing plants.

Vantocil P has been shown to be very effective against Mycobacterium smegmatis and Mycobacterium intracellularis responsible for tuberculosis in pigs.
Vantocil P has also been shown to be effective at eradicating Salmonella pullorum, Salmonella typhimurium, Heamophilus gallinarum, Mycoplasma synoviae and pathogenic E.coli, which are responsible for white diarrhoea, respiratory disease and colibacillosis in chickens.
Vantocil P is based on Arch's highly active biocide poly(hexamethylene biguanide) hydrochloride, also known as PHMB.

Vantocil P is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Vantocil P is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
Vantocil P hydrochloride salt (solution) is used in the majority of formulations.

Vantocil P is a chemical compound that belongs to the biguanide class of disinfectants and antiseptics.
Vantocil P is commonly used for its antimicrobial properties in various applications, ranging from healthcare and personal care to industrial settings.
Vantocil P has broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses.

Vantocil P is also used as a surface disinfectant and is alleged to be suitable for skin disinfection.
Vantocil P, also known as PHMB, polyhexanide or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
The presence of multiple hydrogen bond and chelation sites within Vantocil P renders it of potential interest in the field of supramolecular chemistry.

Vantocil P Antimicrobial is a bactericide manufactured by Excel Industries Limited.
Vantocil P is a broad spectrum, fast acting bactericide for the formulation disinfectants and sanitisers, for use in industrial, institution , agriculture, food beverage and domestic disinfection applications.
Vantocil P is a 20% aqueous solution of poly (hexamethylene biguanide) hydrocloride, also known as PHMB.

Composition: An aqueous solution of Vantocil P. Physical form:
Vantocil P is a slighty opalesscent colorless to pale yellow liquid of pH 4.0- 4.5 and density (at 25øC) 1.14.
Vantocil P is effective in a wide range of industrial disinfection applications , primarily as a solid surface disinfectant.

Vantocil P Antimicrobial manufacturer is Excel Industries Limited but there can be plenty of supplier for supplying or exporting of Vantocil P Antimicrobial substitute or equivalent.
Such substitute chemicals are usually of same chemistry types and can benefit the user in economical aspects.
Vantocil P shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.

Vantocil P is available also as a solid.
Vantocil P is a new environment-friendly cationic water-soluble polymer.
Vantocil P is non-corrosive to skin, and can not be easily absorbed by human organs.

Vitro studies show that Vantocil P is non-toxic to human cells.
Skin irritancy test of rabbits and human hands shows that Vantocil P is non-irritant to animal and human skin.
Vantocil P has a slow effectand does not meet the practical requirementsfor prophylactic antiseptics in this respect.

Vantocil P is a water solution that can be used as a broad-spectrum and high-efficiency disinfectant.
Vantocil P biocide is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of its special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Vantocil P is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride, also known as PHMB.
The combination of the different modes of biocidal action reduces the risk of bacterial resistance, and the product is effective in a wide range of industrial disinfection applications.
Vantocil P disinfectant is a high molecular polymer, which is easy to be washed away.

Vantocil P has a chemical structure characterized by a repeating unit of hexamethylene biguanide.
The polymer consists of a chain of repeating biguanide groups, which are positively charged.
This positive charge contributes to its antimicrobial properties by interacting with the negatively charged components of microorganisms.

storage temp.: Inert atmosphere,Room Temperature
solubility: Water
CAS DataBase Reference: 32289-58-0(CAS DataBase Reference)
FDA UNII: 4XI6112496

Vantocil P has a chemical structure characterized by a repeating unit of hexamethylene biguanide.
The polymer consists of a chain of repeating biguanide groups, which are positively charged.
This positive charge contributes to its antimicrobial properties by interacting with the negatively charged components of microorganisms.

Vantocil P is also used as a surface disinfectant and is alleged to be suitable for skin disinfection.
Vantocil P is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).
Some products containing Vantocil P (PHMB) CAS 32289-58-0 Poly(hexamethylenebiguanide) Hcl are applied for inter-operative irrigation, both before and after surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.

Vantocil P Hcl eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Another good application of Vantocil P Hcl is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.
Vantocil P Antimicrobial can be used alone or incombination with other biocides to create products for awide range of disinfection applications.

Considerable data exists which provides a measure of theintrinsic anti-microbial activity of Vantocil P Antimicrobial, generated via European suspension testprotocols relevant to application in Food, Industrial,Domestic and Institutional Hygiene.Its activity has been further demonstrated under conditionsrepresentative of practical use, and a range of useconcentrations.
However, Vantocil P isrecommended that field tests under practical conditions beundertaken to determine the most cost-effective dose foryour application.

Vantocil P is used as a biocidal agent in various products, including disinfectants, antiseptics, wound care products, contact lens solutions, and preservatives for textiles.
In the medical field, Vantocil P is employed in wound care products to prevent infections in cuts, abrasions, and surgical wounds.
Vantocil P is used in solutions, gels, or impregnated dressings.

Vantocil P Poly(hexamethylenebiguanide) Hcl is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Vantocil P is known for its strong antimicrobial activity.
Vantocil P acts as disinfectant and preservative.

Vantocil P typically exhibits goodbactericidal activity but slower fungicidal and acanthamoebicide activity and provides long term storage capability for the lens.
The usual disinfection time is 4-6 hours. The multipurpose solution containing Polyhexanide or Vantocil P meets FDA and ISO primary standards.
The effects of chlorhexidine diacetate and Vantocil P on the viability of Providencia stuartii strains are described.

Vantocil P is concluded that the phenomenon of ‘regrowth’ results from adhesion to glass containers and the subsequent dispersal of some of these cells into the culture medium.
With the objective of characterizing the occurrence of red leg in Minas Gerais, young and adult frogs with foot and finger ulcers, hemorrhagic effusion on the skin of the ventral region, motor incoordination, high mortality rates in adults and abscesses to necropsy.
In the culture of fragments of damaged skin and abscesses, Aeromonas hydrophila was isolated and identified .

The bactericidal effect of Vantocil P was higher than potassium permanganate, determined by the minimum inhibitory concentration for isolated colonies.
Vantocil P disrupts the cell membranes of microorganisms, leading to their destruction.
This makes Vantocil P effective against a wide range of pathogens.

Vantocil P has a slow effectand does not meet the practical requirementsfor prophylactic antiseptics in this respect.
Although Vantocil P is somewhat less effective than benzalkonium chloride, it is sometimes used instead of benzalkonium because it is less foamproducing under use conditions.
The preparation method of Vantocil P:By a certain proportion of 1, the own bisguanides of 6-and catalyst join in reaction vessel, under nitrogen protection, said mixture is heated to 80-200 DEGC and reacts, react 2-24 hour, reaction terminates, cooling blowing, obtains poly hexamethylene biguanide, poly hexamethylene biguanide aqueous acid is neutralized to pH value 5-9, and performing filtering so as to obtain a polyhexamethylene biguanidine salt.

Vantocil P has demonstrated efficacy against some resilient microorganisms, making it valuable in situations where standard antiseptics may be less effective.
Vantocil P is generally compatible with a variety of materials, including plastics, textiles, and metals, making it suitable for use in different product formulations.
Vantocil P is known for having a low likelihood of inducing resistance in microorganisms.

This property is important in maintaining the effectiveness of the compound over time.
Vantocil P may be used in aquaculture to control bacterial and fungal infections in fish or other aquatic organisms.
Vantocil P may be found in consumer antiseptic products, such as hand sanitizers, providing an additional option for individuals seeking effective antimicrobial solutions.

Vantocil P is incorporated into certain wound dressings to provide an antimicrobial barrier and aid in the healing process.
Vantocil Ps are subject to regulatory oversight, and compliance with relevant regulations ensures the safety and efficacy of the products.
Vantocil P is often used in water-based formulations due to its solubility in water, making it applicable in a variety of liquid products

Vantocil P may be used in veterinary wound care products to manage infections in animals.
Vantocil P is used in some formulations for mold and mildew control, particularly in products designed for damp or humid environments.
Vantocil P may be used in sanitizing solutions for food contact surfaces, helping to control microbial contamination in food processing and preparation areas.

Vantocil P is considered biocompatible, which is an important factor in its use in healthcare and personal care products.
A hydrochloride salt of polyhexamethylene biguanide.
Vantocil P is a high molecular polymer, which is easy to be washed away.

Vantocil P is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Vantocil P is non-toxic to human cells.
Skin irritancy test of rabbits and human hands shows that Vantocil P is non-irritant to animal and human skin.

Vantocil P is a polymer used as a sanitizer or preservative to kill bacteria.
Vantocil P is a broad spectrum and fast acting bactericide which is used for the formulation of disinfectants and sanitisers.

Vantocil P is a new environment-friendly cationic water-soluble polymer.
Vantocil P is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.
Vantocil P is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.

Uses:
Vantocil P is a polymer used as a disinfectant and antiseptic.
Vantocil P may be included in foot care products, such as creams or powders, to provide antimicrobial protection and address issues related to foot hygiene.
Vantocil P is used in some disposable medical products, such as wound dressings and bandages, to help prevent microbial contamination.

In public spaces, such as gyms, swimming pools, and public restrooms, Vantocil P may be used in cleaning solutions and disinfectants to control the spread of infections.
Vantocil P can be incorporated into the manufacturing of hospital bed linens and textiles to provide an additional layer of protection against microbial contamination.
Vantocil P may be used in the preservation of hemodialysis fluids, helping to maintain the sterility of these solutions used in renal replacement therapy.

Vantocil P is commonly used in personal care and cosmetic products, including hand sanitizers, soaps, shampoos, and skin cleansers.
Vantocil P helps in preventing the growth of bacteria and fungi on the skin and in the products themselves.
In addition to wound care products, Vantocil P is sometimes used in medical settings for skin disinfection and as a coating for certain medical devices.

Vantocil P is found in some household items like disinfectant wipes and cleaning solutions.
Vantocil P is used in swimming pools, hot tubs, and other water systems as a disinfectant to control the growth of algae, bacteria, and other microorganisms.
Vantocil P-treated textiles, such as clothing and bedding, may offer antimicrobial properties, reducing the risk of bacterial and fungal growth.

Long-term care facilities may use products containing Vantocil P as part of infection control measures to reduce the risk of healthcare-associated infections among residents.
Vantocil P is sometimes included in insect repellent formulations for its antimicrobial properties, providing additional protection against microbial contamination.
Vantocil P may be found in household disinfectants and cleaning products, contributing to their antimicrobial efficacy.

Vantocil P may be used in agricultural and horticultural settings to control microbial contamination in soil, plant care products, or agricultural equipment.
Vantocil P has been explored for potential use in biodegradable plastics, providing a way to control microbial degradation in certain plastic materials.
Vantocil P may be included in wound irrigation solutions to prevent infections during the cleaning of wounds.

Vantocil P may be used in the preservation of construction materials, such as coatings and sealants, to inhibit microbial growth.
Vantocil P can be applied in the preservation of wood and timber products to protect against decay caused by fungi and bacteria.
In healthcare settings, Vantocil P may be used for the disinfection of respiratory equipment to prevent the growth of harmful microorganisms.

Vantocil P is included in some preventive skin care products, such as barrier creams, to protect the skin from microbial contamination.
Vantocil P can be used in swimming pool water treatment to control bacteria and other microorganisms, contributing to water hygiene.
Vantocil P is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.

Vantocil P can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eels, Aeromonas hydrophilic, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.
In dermatological use, it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide.
Vantocil P has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).

Designed to be used for regular sanitizing of contaminated linen, garments & fabrics as part of the laundering process.
Vantocil P can be used in home-type or commercial laundering machines.
Ideal for use in health care laundry applications.

Vantocil P Antimicrobial is not compatible with high levels of chlorine.
Articles treated with Vantocil P Antimicrobial should not be subsequently bleached with chlorine.
Vantocil P Antimicrobial is not compatible with common soap and anionic detergents.

Vantocil P is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceutical, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, sanitary pads, clothes, etc.
Vantocil P is used to control bacterial and fungal infections in fish or other aquatic organisms.
Vantocil P contributes to the preservation of cosmetic and personal care products, preventing microbial growth and ensuring product stability over time.

Vantocil P may be used in disinfection protocols in hospitality settings, such as hotels and leisure facilities, to control the spread of infections.
Vantocil P is used in some residential cleaning products to provide effective antimicrobial action.
Vantocil P may be incorporated into formulations for sports equipment to prevent microbial contamination and odors.

Vantocil P may be used in air fresheners to inhibit the growth of bacteria and fungi in the product.
Vantocil P is used in the stabilization of fabric linings in shoes.
Biguanide solution used in cleaning contact lenses.

Vantocil P is used in dermatological formulations for the treatment of various skin conditions, including infections or inflammatory skin disorders.
Vantocil P is included in mouthwashes and oral care products for its antimicrobial properties.
Vantocil P helps control bacteria in the oral cavity, contributing to oral hygiene.

Vantocil P is investigated for potential biomedical applications, including drug delivery systems and tissue engineering, due to its biocompatibility and antimicrobial properties.
Vantocil P is employed in healthcare settings to help prevent infections in wounds, surgical sites, and catheter-related applications.
PHMB is often included in waterless hand sanitizers due to its antimicrobial properties.

These sanitizers are convenient for situations where traditional handwashing is not possible.
Some foot care products, such as foot creams and powders, may incorporate Vantocil P to help prevent the growth of bacteria and fungi that can contribute to foot odor and infections.
Vantocil P can be used in agriculture as a disinfectant for equipment, tools, and surfaces to control microbial contamination.

Certain consumer products, such as antimicrobial wipes, household cleaners, and deodorants, may include PHMB to provide protection against microbes.
Vantocil P is sometimes used in veterinary products, including shampoos and wound care solutions for animals.
Vantocil P can be incorporated into various industrial processes to control microbial contamination in water systems, manufacturing equipment, and other settings where microbial growth can be problematic.

In addition to contact lens solutions, Vantocil P may be used in ophthalmic solutions for eye care.
Vantocil P can serve as a preservative in cosmetic formulations, helping to prevent the growth of microorganisms in products like lotions and creams.
Vantocil P is sometimes incorporated into wound dressings and bandages to help prevent infections in cuts and abrasions.

In some formulations, Vantocil P may be included in mouthwashes for its antimicrobial properties.
Vantocil P may be used in veterinary wound care products to manage infections in animals.
Vantocil P is used in some formulations for mold and mildew control, particularly in products designed for damp or humid environments.

Vantocil P may be used in sanitizing solutions for food contact surfaces, helping to control microbial contamination in food processing and preparation areas.
Vantocil P can be found in consumer antiseptic products, such as hand sanitizers, providing an additional option for individuals seeking effective antimicrobial solutions.

Safety Profile:
On the 20th of April 2018, the european commission decided to ban preservative uses of Vantocil P PT9 (Fibre, leather, rubber and polymerised materials preservatives).
Vantocil P’s still allowed for uses as disinfectants PT2 (Disinfectants and algaecides not intended for direct application to humans or animals).
Vantocil P was classified as category 2 carcinogen by the European Chemical Agency, but it is still allowed in cosmetics in small quantities if exposure by inhalation is impossible.

Vantocil P is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Concentrated solutions of Vantocil P may cause irritation to the skin and eyes.
Furthermore, Vantocil P has been declared as a candidate for substitution by the ECHA.

While Vantocil P is generally considered safe for use in approved concentrations in various products, it's important to follow product instructions and guidelines.
Concentrations and formulations may vary, and excessive use or exposure can lead to irritation or other adverse effects.
As with any chemical, it's crucial to use products containing Vantocil P responsibly and as directed.
VANTOCIL TG
VANTOCIL TG Antimicrobial is effective in a wide range of industrial disinfection applications, primarily as a solid surface disinfectant.
VANTOCIL TG is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.

CAS Number: 32289-58-0
Molecular Formula: C10H23N5
Molecular Weight: 213.32312
EINECS No: 1308068-626-2

VANTOCIL TG is best known for its broad-spectrum antimicrobial and antifungal activity.
It is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu.

VANTOCIL TG, often abbreviated as VANTOCIL TG HCl, is a specific form of the antimicrobial polymer Poly(hexamethylenebiguanide).
It is a cationic polymer that contains positively charged biguanide groups.

The hydrochloride form refers to the presence of chloride ions associated with the polymer, which contribute to its water solubility and effectiveness as an antimicrobial agent.
VANTOCIL TG Antimicrobial is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.
It is a 20% aqueous solution of VANTOCIL TG, also known as PHMB.

VANTOCIL TG Antimicrobial is used in industrial, institutional, agricultural, food, beverage and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants.

VANTOCIL TG is a polymer composed of repeating units of hexamethylenebiguanide.
Each repeating unit contains positively charged guanidine groups.
VANTOCIL TG antimicrobial in bath wipes for all pets Thai Hygienic, Thailand, recently introduced their 'Spets'™ Bath Tub wipes containing Arch's VANTOCIL TG antimicrobial.

VANTOCIL TG, the active ingredient in VANTOCIL TG antimicrobial range is a fast-acting and broad spectrum bactericide with a wide formulation latitude.
Consequently, by careful selection of appropriate co-formulants, a wide range of professional and domestic products can be formulated which meet the stringent demands of today's disinfection and hygiene industries.

VANTOCIL TG, like other forms of PHMB, exhibits potent antimicrobial properties due to its ability to disrupt microbial cell membranes.
The positively charged biguanide groups interact with negatively charged components of microbial membranes, leading to membrane disruption and cell death.

storage temp.: Inert atmosphere,Room Temperature
solubility: Water
Assay: 97%
Composition: An aqueous solution of PHMB
Active Agent: 20% w/w
Physical Form: Slightly opalescent colourless to pale yellow liquid
Viscosity at 25°C: 5 mPa s.
pH at 25°C: 5.0-6.0
Boiling Point: 102°C
Storage Stability: Stable under normal conditions of storage down to 0°C.
Flash Point: Boils without flashing
Density at 25°C: 1.04

VANTOCIL TG is a kind of cationic surfactant, belonging to nonoxidizing boicide.
It can efficiently withhold algae propagation and sludge reproduction.
VANTOCIL TG also has dispersing and penetrating properties, can penetrate and remove sludge and algae, has advantages of low toxicity, no toxicity accumulation, soluble in water, convenient in use, unaffected by water hardness.

VANTOCIL TG can be also used as anti-mildew agent, antistatic agent, emulsifying agent and amendment agent in woven and dyeing fields.
VANTOCIL TG form enhances its water solubility, making it suitable for various aqueous formulations.
This solubility allows VANTOCIL TG to be easily incorporated into liquids, gels, and other water-based products.

VANTOCIL TG antimicrobial action is based on its interaction with microbial cell membranes.
The positively charged biguanide groups are attracted to the negatively charged components of microbial membranes.
The disruption of cell membranes leads to cell death and prevents microbial growth.

In healthcare settings, VANTOCIL TG products are used for; Disinfection of surfaces, medical equipment, and instruments.
Wound care to prevent infection and promote healing, especially in chronic wounds.

VANTOCIL TG is a common ingredient in personal care products like: Antibacterial soaps and body washes for everyday hygiene.
VANTOCIL TG textiles serve multiple purposes, including: Antimicrobial fabrics in healthcare settings to reduce microbial contamination on textiles.
Odor reduction in sportswear and activewear through inhibition of bacteria causing bad odors.

VANTOCIL TG application in water treatment extends to: Swimming pools and spas, where it controls bacterial and algal growth to maintain water hygiene.

In cosmetic and toiletry products, VANTOCIL TG serves as a preservative by preventing the growth of potentially harmful microorganisms.
This helps extend the shelf life of products and ensures their safety for consumer use.

As with all antimicrobial agents, considerations about VANTOCIL TG's potential impact on the environment are important.
Research and regulatory measures aim to address any potential ecological consequences.

VANTOCIL TG-containing products are subject to regulations and guidelines set by health and safety authorities in various regions.
Proper use and adherence to recommended concentrations are essential to ensure product safety.

Preparation
The preparation method of VANTOCIL TG:By a certain proportion of 1; the own bisguanides of 6-and catalyst join in reaction vessel; under nitrogen protection, said mixture is heated to 80-200 DEGC and reacts, react 2-24 hour; reaction terminates; cooling blowing, obtains poly hexamethylene biguanide, poly hexamethylene biguanide aqueous acid is neutralized to pH value 5-9; and performing filtering so as to obtain a VANTOCIL TG salt.

Uses
VANTOCIL TG is a polymer used as a disinfectant and antiseptic.
In dermatological use, it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide.
VANTOCIL TG has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).

VANTOCIL TG is also used as a surface disinfectant and is alleged to be suitable for skin disinfection.
VANTOCIL TG has a slow effectand does not meet the practical requirementsfor prophylactic antiseptics in this respect.
Although VANTOCIL TG is somewhat less effective than benzalkonium chloride, it is sometimes used instead of benzalkonium because it is less foamproducing under use conditions.

VANTOCIL TG is also used to preserve wet wipes; to control odor in textiles; to prevent microbial contamination in wound irrigation, sterile dressings; to deodorize vacuums and toilets; to disinfect medical/dental utensil and trays, farm equipment,
animal drinking water and hard surfaces for food handling institutions and hospitals.

VANTOCIL TG can sometimes be used in combination with other antimicrobial agents to create synergistic effects, enhancing overall antimicrobial activity.
VANTOCIL TG has been explored for use in drug delivery systems, where its antimicrobial properties could be harnessed to prevent infections at the site of drug delivery, such as in medical implants.

VANTOCIL TG has found applications in dental and oral care products, such as mouthwashes and toothpaste, as an antimicrobial agent to maintain oral hygiene.
VANTOCIL TG can be used as a surface disinfectant in the food industry to prevent bacterial contamination on equipment and food contact surfaces.

VANTOCIL TG has been investigated for its potential use in aquaculture to control bacterial infections in fish and shrimp farming.
VANTOCIL TG has been used in veterinary medicine for wound care in animals and to prevent infections in pet care products.

VANTOCIL TG's efficacy against various pathogens and its potential to combat emerging microbial resistance.
The stability of VANTOCIL TG in different formulations and under varying conditions is an important consideration for product development and shelf life.

The use of VANTOCIL TG varies by region and industry due to regulatory standards, consumer preferences, and application-specific requirements.
Proper education and training for professionals using VANTOCIL TG-containing products are important to ensure effective and safe application.

As with any antimicrobial agent, the potential environmental impact of VANTOCIL TG must be carefully considered, and efforts toward sustainable practices should be promoted.
Consumer awareness and perception of antimicrobial agents in products are factors that can influence market adoption and acceptance.

Industry collaboration, research initiatives, and regulatory agencies work together to ensure the responsible use of VANTOCIL TG and its derivatives.
VANTOCIL TG is used for surface disinfection, medical equipment sanitation, and wound care to prevent infections and promote healing.

VANTOCIL TG is found in products like antibacterial soaps, shampoos, body washes, and hand sanitizers for personal hygiene and protection against harmful microorganisms.
VANTOCIL TG is applied to textiles to create antimicrobial fabrics used in healthcare, sportswear, and everyday clothing to reduce microbial growth and odors.

In swimming pools and spas, VANTOCIL TG helps control bacterial and algal growth, maintaining water hygiene.
VANTOCIL TG-based formulations are used in cleaning products for effective antimicrobial cleaning.
VANTOCIL TG serves as a preservative in cosmetics and toiletries, ensuring product safety and extending shelf life.

Health and Safety
The VANTOCIL TG Antimicrobial Safety Data Sheet may be supplied upon request.
VANTOCIL TG should be read and understood by all supervisory personnel and employees before using this product.

On the 20th of April 2018, the european commission decided to ban preservative uses of VANTOCIL TG (Fibre, leather, rubber and polymerised materials preservatives).
VANTOCIL TG’s still allowed for uses as disinfectants PT2 (Disinfectants and algaecides not intended for direct application to humans or animals).
As with all antimicrobial agents, the safe and effective use of VANTOCIL TG relies on adherence to recommended concentrations, guidelines, and regulatory standards.

Synonyms
32289-58-0
polyhexamethylene biguanide hydrochloride
polihexanide hydrochloride
polihexanide HCl
poly(hexamethylenebiguanide) hydrochloride
hexamethylenediamine polymer hydrochloride
Cosmoquil CQ
Cosmocil
PHMB hydrochloride
poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) hydrochloride
Prontosan
poly(hexamethylene) biguanide hydrochloride
Prontoderm
TriGene
Reputex 20
Vantocil 1B
Vantocil TG
Vantosan
PHMB-HCl
CHEBI:149534
VANTOCIL TG
pétrolatum, gelée de pétrole, No CAS: 8009-03-8, La vaseline officinale est un médicament ; il s'agit d'une pommade employée comme traitement d'appoint des lésions d'irritation, de brûlure et de sécheresse cutanée. Son utilisation la plus célèbre est la forme utilisée pour le soin des lèvres et pour le traitement de la chéilite ou de la perlèche. En effet, elle est pratiquement inerte à la peau et n'entre dans aucune réaction chimique. Elle favorise la cicatrisation des lésions par sa propriété à ne pas laisser l'eau s'évaporer ni à y entrer comme dans le cas d'une plaie endo-nasale qui est en permanence humide et donc difficilement cicatrisable ou dans le traitement d'une épistaxis. Elle agit comme barrière mécanique contre la pullulation des germes, et la présence de phénols, même à quantité minime, agit comme bactéricide. Elle entre aussi dans la composition de la majorité des lotions en cosmétique, utilisée comme excipient. À cause de ses propriétés moléculaires, la vaseline est utilisée comme écran solaire qui filtre certains ultraviolets.(Keerulise koostisega süsivesinike segu, mis saadakse pooltahke massina parafiinse jääkõli deparafiinimisel. Koosneb peamiselt küllastunud kristalsetest ja vedelatest süsivesinikest, mille süsiniku aatomite arv on valdavalt üle C25.) (et) (Složeni sastav ugljikovodika dobiven kao polukruta tvar kod odvoštavanja parafinskog ostatnog ulja. Sastoji se pretežito od zasićenih kristaličnih i tekućih ugljikovodika koji imaju broj ugljikovih atoma pretežito viši od C25.) (hr) [Kompleks blanding av hydrokarboner dannet som halvfast stoff fra avvoksing av parafinrestolje. Består for det meste av mettede, krystallinske og flytende hydrokarboner hovedsakelig større enn C25.] (no) [Komplekss ogļūdeņražu savienojums, ko iegūst kā biezu masu, atdalot vaskus no parafīnu atlikuma eļļas. Pārsvarā tajā ir piesātināti kristāliski un šķidri ogļūdeņraži, kuros oglekļa atomu skaits galvenokārt ir lielāks nekā C25.] (lv) [Komplexe Kombination von Kohlenwasserstoffen, die als Semifeststoff beim Entwachsen von paraffinhaltigem Rückstandsöl erhalten wird. Besteht vorherrschend aus gesättigten kristallinen und flüssigen Kohlenwasserstoffen mit Kohlenstoffzahlen vorherrschend größer als C25.] (de) [Komplexná zmes uhľovodíkov získavaná v podobe polotuhej látky odvoskovaním alkánového zvyškového oleja. Pozostáva predovšetkým z nasýtených kryštalických a kvapalných uhľovodíkov, s počtom atómov uhlíka prevažne väčším ako C25.] (sk) [O combinaţie complexă de hidrocarburi, obţinuta ca semisolid prin deparafinarea uleiurilor reziduale parafinice. Se compune în principal din hidrocarburi saturate cristaline şi lichide cu număr de atomi de carbon mai mare de C25.] (ro) [Paraffinos maradék olajból viaszmentesítéssel, félig szilárd anyagként előállított, bonyolult összetételű szénhidrogén elegy. Főleg C25 fölötti szénatomszámú, telített, kristályos és folyékony szénhidrogéneket tartalmaz.] (hu) [Složitá směs uhlovodíků získaná jako polotuhá látka z odparafinování zbytkového oleje z parafinické ropy. Je složena převážně z nasycených krystalických a kapalných uhlovodíků s počtem uhlíkových atomů převážně větším než C12.] (cs) [sudėtingas angliavandenilių mišinys, gautas kaip pusiau kieta medžiaga deparafinuojant parafino alyvos likutį. Jo svarbiausi komponentai yra sotieji kristaliniai ir skystieji angliavandeniliai, turintys daugiausiai daugiau negu C25 anglies atomus.] (lt) [Комплексна комбинация от въглеводороди, получена като полутвърдо вещество от депарафинизирането на остатъчен суров парафин. Състои се основно от наситени кристални и течни въглеводороди с брой на въглеродните атоми преобладаващо по-голям от С25.] (bg) Amorfni parafin (hr) Combinación compleja de hidrocarburos obtenidos como un semisólido de la desparafinación del aceite residual parafínico. Compuesta fundamentalmente de hidrocarburos saturados líquidos y cristalinos con un número de carbonos en su mayor parte superior a C25. (es) Combinaison complexe d'hydrocarbures obtenue sous forme semi-solide lors du déparaffinage d'huile résiduelle paraffinique. Se compose principalement d'hydrocarbures saturés cristallins et liquides dont le nombre de carbones est en majorité supérieur à C25. (fr) Combinazione complessa di idrocarburi, ottenuta in forma semisolida dalla deparaffinazione di olio residuo paraffinico. AE costituito in prevalenza da indrocarburi liquidi e cristallini saturi con numero di atomi di carbonio prevalentemente superiore a C25. (it) Een complexe verzameling van koolwaterstoffen, verkregen als een halfvaste stof bv het van was ontdoen van paraffinische residu-olie. Het bestaat voornamelvk uit verzadigde kristallvne en vloeibare koolwaterstoffen, overwegend groter dan C25. (nl) En sammensat blanding af carbonhydrider udvundet som et halvfast stof fra afvoksning af paraffinrestolie. Den består overvejende af mættede krystallinske og flydende carbonhydrider, overvejende større end C25. (da) Kompleksna kombinacija poltrdih ogljikovodikov dobljenihpri deparafinizaciji parafinskih rezidualnih olj. Sestavljenaje predvsem iz nasičenih kristalnih in tekočihogljikovodikov, ki imajo število ogljikov pretežno večjekot C25. (sl) Petrolaatum (et) Petrolato (it) Petrolatos (pt) Petrolatum (cs) Petrolátum (hu) pretolato (pt) Pétrolatum (fr) Uma combinação complexa de hidrocarbonetos obtida como um semi-sólido na desparafinagem de óleo residual parafínico. BE constituída predominantemente por hidrocarbonetos saturados cristalinos e líquidos com números de átomos de carbono predominantemente superiores a C25. (pt) vaezlin (sl) Vaseliini (fi) Vaselin (da) Vaselina (es) vazelin (sl) vazelinas (lt) vazelīns (lv) Wazelina (pl) Złożona mieszanina węglowodorów otrzymywana jako substancja półpłynna przez odparafinowanie parafinowego oleju pozostałościowego. Składa się przede wszystkim z nasyconych krystalicznych i ciekłych węglowodorów o liczbie atomów węgla głównie powyżej C25. (pl) Ββαζελίνη (el) Петролатум (bg) Петролатум (вазелин) (bg)
VANTOCİL IB
Vantocil IB, also known as PHMB or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
Vantocil IB is a polymer used as an antiseptic.
The presence of multiple hydrogen bond and chelation sites within Vantocil IB renders it of potential interest in the field of supramolecular chemistry.

CAS Number: 28757-47-3
Molecular Formula: C8H19N5.ClH
Molecular Weight: 221.734
EC Number: 923-111-4

Vantocil IB shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Vantocil IB is available also as a solid.

Vantocil IB is a substance used in industrial, institutional, agricultural, food, beverage and home disinfection applications.
Vantocil IB is a broad spectrum, fast acting bactericide for disinfectant and disinfectant formulation.

Vantocil IB, often abbreviated as PHMB, is a polymer with antimicrobial properties.
It belongs to a class of antimicrobial agents known as biguanides.
Vantocil IB is used in various applications, primarily as a disinfectant, preservative, and biocide.

Vantocil IB has gained attention for its effectiveness against a wide range of microorganisms, including bacteria, viruses, and fungi.
Vantocil IB is composed of repeating units of hexamethylenebiguanide, which is a biguanide compound with multiple guanidine functional groups.

Vantocil IB the specific chemical structure can vary based on the degree of polymerization.
Vantocil IB is a structure that is also found in dermatological use.
Vantocil IB is an effective polymer against some ailments.

Vantocil IB (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic.
In dermatological use, it is spelled Vantocil IB (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide.
Vantocil IB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.

Products containing Vantocil IB are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.

Vantocil IB eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Stakeholders, including manufacturers, regulators, and consumers, play a role in ensuring the responsible use of Vantocil IB-based products and mitigating potential environmental impact.

Molecular Weight: 185.27
XLogP3-AA: 0.5
Exact Mass: 185.16404563
Monoisotopic Mass: 185.16404563
Topological Polar Surface Area: 103 Ų
Heavy Atom Count: 13
Color: white powder or colorless liquid
Form: liquid
Appearance: Colorless or light-yellow solid
Active ingredient: ≥99%
Water soluble: 100% soluble
Odor: Light ammonia smell
Moisture content: ≤0.5%
Water insoluble matter: ≤0.1%
PH in 1% aqueous solution: >1

Vantocil IB by Arxada is an aqueous solution.
Vantocil IB is a highly effective preservative for use in a wide variety of applications including oil-in-water and water-in-oil emulsions, industrial reagents, silicone systems, cellulose solutions and oil recovery systems.
Can also be used to preserve aqueous-based adhesives (such as animal glues, latex adhesives based on polyvinyl acetate, PVA, starch, dextrin, casein and other glues, and latex adhesives intended for food packaging applications).

Recommended usage level of Vantocil IB is 500-5000 ppm.
Vantocil IB is included in products used for disinfection of skin and mucous membranes before and after surgery.
Vantocil IB is a medically viable compound used for post-operative dressings, surgical and non-surgical wound dressings.

Vantocil IB is an important substance used for chronic wounds such as foot ulcers and burns.
Vantocil IB's antimicrobial activity stems from its ability to disrupt the integrity of microbial cell membranes, leading to cell lysis and death.
It is effective against both gram-positive and gram-negative bacteria, as well as viruses and fungi.

Vantocil IB Antimicrobial is a broad spectrum, fast acting bactericide for the formulation of disinfectants and sanitisers.
Vantocil IB is a 20% aqueous solution of poly (hexamethylene biguanide) hydrochloride (PHMB).
Vantocil IB Antimicrobial is produced for use in industrial, institutional, agricultural, food, beverage, and domestic disinfection applications, primarily as a solid surface disinfectant, specifically for hospitals, veterinary establishments, dairies, milking parlors, breweries, air-conditioning units, and pasteurizers in canned food & beverage bottling plants.

Vantocil IB's antimicrobial activity is broad-spectrum, making it effective against a wide range of microorganisms.
It has a relatively low toxicity profile when used at appropriate concentrations.
Vantocil IB can have a long-lasting effect, providing extended protection against microbial growth.

Vantocil IB's antimicrobial mechanism involves its interaction with microbial cell membranes.
The positively charged guanidine groups in the Vantocil IB molecules are attracted to the negatively charged components of microbial cell membranes.

This interaction disrupts the integrity of the cell membrane, leading to leakage of cellular contents, disruption of cellular processes, and ultimately, cell death.
Vantocil IB has demonstrated efficacy against a broad spectrum of microorganisms, including; Gram-positive and gram-negative bacteria, enveloped and non-enveloped viruses, fungi and yeasts.
This broad-spectrum activity contributes to its usefulness in a variety of applications where protection against multiple types of microorganisms is desired.

In healthcare settings, Vantocil IB-based solutions are used for; surface disinfection in hospitals, clinics, and laboratories, disinfection of medical equipment and devices, wound care and prevention of infection in chronic wounds.
Vantocil IB is available in various formulations, including aqueous solutions, gels, creams, and powders.
These formulations are tailored to specific applications, such as wound care, surface disinfection, and textile treatment.

The concentration of Vantocil IB in products can vary depending on the intended use.
For example, wound care products might have higher concentrations to ensure effective antimicrobial activity, while consumer products may have lower concentrations for skin compatibility.
Vantocil IB's mechanism of action, which targets the cell membrane, is different from many traditional antibiotics.

Vantocil IB unique mode of action makes it less likely to contribute to antibiotic resistance.
Vantocil IB's potential in combating antibiotic-resistant bacteria has attracted attention as a valuable alternative in infection control.
Vantocil IB has been used in wound care products, including dressings, gels, and solutions.

Vantocil IB helps prevent infections in both acute and chronic wounds, promoting healing and reducing the risk of complications.
Vantocil IBs broad-spectrum antimicrobial activity makes it effective against various microorganisms commonly found in wounds.

Vantocil IB-treated textiles have found applications in a range of industries, from healthcare to sportswear.
In healthcare settings, Vantocil IB-treated fabrics contribute to infection control by reducing the risk of bacterial contamination and biofilm formation on textiles used in hospitals and clinics.

Uses
Vantocil IB is an environmental-friendly Cationic Polymer.
Vantocil IB is water soluble and the aqueous solution is colorless and odorless, broad-spectrum, high-efficiency,low toxicity, good stability, non-flammable and non-explosive.
Normally non-corrosive to stainless steel, stainless copper, carbon steel, wood, plastic, etc.

Vantocil IB is a high molecular polymer, which is not easily absorbed by tissues, has no corrosive effect, has good stability and is easy to rinse, good biocompatibility.
Vantocil IB is used in healthcare settings as a disinfectant for surfaces, medical equipment, and wound care products.
Wound dressings containing Vantocil IB are used to prevent infection and promote healing in chronic wounds.

Vantocil IB is found in some personal care products, such as antibacterial soaps, shampoos, and body washes.
Vantocil IB is used as a preservative in cosmetics and toiletries to prevent the growth of harmful microorganisms.
Vantocil IB is used to disinfect surfaces, equipment, and instruments in healthcare facilities to reduce the risk of healthcare-associated infections.

Vantocil IB-containing wound dressings and solutions are used to prevent infections in chronic and acute wounds, promoting healing.
Vantocil IBis found in antibacterial soaps, body washes, and hand sanitizers for personal hygiene.
Vantocil IB serves as a preservative in cosmetics and toiletries, preventing the growth of harmful microorganisms and extending product shelf life.

Vantocil IB-treated textiles, including clothing, bedding, and healthcare fabrics, help control microbial growth, reduce odors, and enhance fabric hygiene.
Sportswear and activewear treated with Vantocil IB resist odor-causing bacteria, making them ideal for athletic activities.

Vantocil IB is used to control bacterial and algal growth in swimming pools and spas, contributing to water hygiene and safety.
Vantocil IB-based formulations are used in cleaning products for surfaces, equipment, and areas where antimicrobial protection is necessary.
Vantocil IB is sometimes used in veterinary settings for wound care and hygiene in animals.

Vantocil IB may be found in various consumer products like household disinfectants, cleaning wipes, and fabric sprays.
Vantocil IB can be incorporated into water-based products to provide antimicrobial properties.
This includes various liquid formulations and aqueous solutions.

Vantocil IB is used as an antimicrobial treatment for textiles, including clothing, bedding, and healthcare fabrics.
It helps prevent the growth of odor-causing bacteria and microbes that can lead to fabric degradation.

Vantocil IB is used in swimming pools, spas, and water treatment systems to control the growth of bacteria and algae.
Vantocil IB-based formulations are used in cleaning products to provide antimicrobial protection on various surfaces.

Safety Considerations:
While Vantocil IB is generally considered safe when used according to guidelines, it's important to follow recommended concentrations and safety precautions to avoid any potential adverse effects.
Vantocil IB is considered safe for various applications when used within recommended concentrations and guidelines.

Vantocil IB has a relatively low potential for causing skin irritation when used as directed.
Regulatory agencies in different regions provide guidelines for the use of Vantocil IB in various applications, ensuring safety for consumers and the environment.

Environmental Considerations:
The environmental impact of Vantocil IB depends on factors such as its persistence, potential for bioaccumulation, and biodegradability.
There have been discussions about its potential environmental consequences, particularly when used in high concentrations or when released into the environment.

Synonyms
polihexanide
28757-47-3
Baquacil
cosmocil
Lavasept
PHMB
PHMB polymer
polihexanide hydrochloride
polyhexamethylenbiguanid
polyhexamethylen-biguanide
polyhexamethylenbiguanide
poly(hexamethylene biguanide)
polyhexamethylene biguanide
Vantocil IB hydrochloride
polyhexamethylene biguanide hydrochloride
Vantocil IB
Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl)
poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride
Vantocil
Vantocil IB of Vantocil
C031233

VARONIC K 202
DESCRIPTION:


Varonic K 202 is an ethoxylated amine used in household and I&I cleaners, textile, agriculture, leather, metal working, paint, resin and petroleum.
Varonic K 202 is 2 mole propoxylate of primary coco amine.
Varonic K 202 is an excellent emulsifier and wetting agent.



CAS NUMBER: 68516-06-3



DESCRIPTION:

Varonic K 202 provides alkalinity to formulations.
Varonic K 202 works well in acidic and alkaline formulas.

Varonic K 202 has excellent hard water tolerance, acid and alkaly stability, quat compatibility and tend to inhibit corrosion in some applications.
Due to the presence of Varonic K 202 chains and a positive nitrogen, propoxylated amines show an excellent combination of nonionic and cationic behavior.



USAGE:

-household
-I&I cleaners
-textile
-agriculture
-leather
-metal working
-paint
-resin
-petroleum.



APPLICATION:

-Oil/water emulsifiers
-Dye leveling
-Surface tension reduction
-Anticorrosives
-Latex viscosity agents
-Dispersing agents
-Hard surface cleaner
-Chemical itermediate




PROPERTIES:

-Appearance at 25 C: slight yellow to clear liquid
-Tertiary amine wt. %: 99 min.
-Color: 10 max.
-Water, wt. %: 0.2 max.
-Flash point: > 212
-pH: 9-11
-Density: 0.92




SYNONYM:

Genamin C 050
Genamin C 200
K 215
Kostat P 650/5
Lutensol FA 12K
Lutensol FA 5K
Mazeen C 2
Mazeen C 5
Nissan Nymeen F 215
Noramox C
Noramox C 11
Noramox C 2
Nymeen F 202
Nymeen F 215
Optamine PC 5
PPEM 239
Rhodameen C 5
Rofamin KD 3
Sinopol 412
Surfonic C 2
Variquat 1215
Varonic K 202
Varonic K 205
Varonic K 205LC
Varonic K 209
Varonic K 210
Varonic K 210LC
Varonic K 215
Varonic K 215LC
Witcamine 302
Witcamine 305





























VARONIC K 210
DESCRIPTION:

Varonic K 210 is an ethoxylated amines for use in household hard surface cleaners, metal cleaners, anticorrosives, latex viscosity modification, and dispersing agents.
Varonic K 210 is a ten mole ethoxylate of coconut amine.
Varonic K 210 is a very effectives raw material.



CAS NUMBER: 61791-14-8

EC NUMBER: 500-152-2



DESCRIPTION:

Varonic K 210 is an amine ethoxylate based on cocos fatty amine.
Varonic K 210 can be combined with all types at nonionic and cationic surfactants, and are compatible with anionic products on a case-by-case level.
Varonic K 210 is resistant to most chemicals at typical concentrations used and insensitive to water hardness.



USES:

-household hard surface cleaners
-metal cleaners
-anticorrosives
-latex viscosity modification
-dispersing agents



PROPERTIES:

-Purity: 95%, 99%
-Appearance:liquid or solid



SYNONYM:

(Coconutoil alkyl)amine, ethoxylated
Amiet 102
Amines, cocoalkylbis(polyoxyethylene)
Amines, coconut, ethoxylated
Arosurf MG 160
Atmer169
Berol 307
Berol 397
Blaunon L 210;Blaunon L 220
Chemeen C 10
ChemeenC 12G
Chemeen C 2
Crisamine PC 2
Crodamet 02
Crodamet C 20
Crodamet C 5
Esomine C 25
Ethomeen C
Ethomeen C 12
Ethomeen C 15
Ethomeen C 20
EthomeenC 25
Ethox CAM 15
Ethox CAM 2
Ethoxylated coco alkyl amines
Ethylan TLM
GN8361
Genamin C
Genamin C 020
Genamin C 050
Genamin C 200
K 215
Kostat P650/5
Lutensol FA 5K
Mazeen C 2
Mazeen C 5
Nissan Nymeen F 215
Noramox C
Noramox C 11
Noramox C 2
Nymeen F 215
Optamine PC 5
PPEM 239
Rhodameen C5
Rofamin KD 3
Surfonic C 2
Variquat 1215
Varonic K 202
Varonic K 205
Varonic K 205LC
Varonic K 209
Varonic K 210
Varonic K 210LC
Varonic K 215
Varonic K 215LC
Witcamine 302
Witcamine 305















VARONIC K 215
DESCRIPTION:

Varonic K 215 is an ethoxylated amines for use in household hard surface cleaners, metal cleaners, anticorrosives, latex viscosity modification, and dispersing agents.
Varonic K 215 is a 15 mole ethoxylate of coco
primary amine.



CAS NUMBER: 61791-14-8



DESCRIPTION:

Due to the presence of dual ethylene oxide chains and a positive nitrogen, Varonic K 215 shows excellent combination of non-ionic and cationic behavior.
Varonic K 215 is an excellent co-emulsifier in microemulsions as well as wetting agent.
Varonic K 215 is an ethoxylate of coco primary amines.



APPLICATION:

-Automotive Care
-Heavy Duty Cleaning
-Household Cleaning



TYPICAL PROPERTIES:

-Appearance at 25 C: Liquid
-pH-Value (10% IPA/water): 9-11
-Neutralization Equivalent: 860-900
-Specific gravity at 25 C: 1.03
-Flash Point, C: > 100 C
-Viscosity at 45 C mPas: 62
-Viscosity at 25 oC mPas: 171
-Color, Gardner (’63): 9 max
-Tertiary amine, wt. %: 95%
-Water content, %: < 0.5



BENEFITS:

-High hydrophilicity
-Adds alkalinity to the formulation
-Corrosion inhibitor
-Hard water tolerance
-Non-gelling
-Works well in acidic and alkaline formulations



FEATURES:

-alkalinity to the formulation
-high hydrophilicity
-dye transfer inhibitors
-corrosion inhibitor
-hard water tolerance
-non-gelling
-work well in acidic and alkaline formulas
-Degreasing




SYNONYM:

(Coconutoil alkyl)amine, ethoxylated
Amiet 102
Amines, cocoalkylbis(polyoxyethylene)
Amines, coconut, ethoxylated
Arosurf MG 160
Atmer169
Berol 307
Berol 397
Blaunon L 210;Blaunon L 220
Chemeen C 10
ChemeenC 12G
Chemeen C 2
Crisamine PC 2
Crodamet 02
Crodamet C 20
Crodamet C 5
Esomine C 25
Ethomeen C
Ethomeen C 12
Ethomeen C 15
Ethomeen C 20
EthomeenC 25
Ethox CAM 15
Ethox CAM 2
Ethoxylated coco alkyl amines
Ethylan TLM
GN8361
Genamin C
Genamin C 020
Genamin C 050
Genamin C 200
K 215
Kostat P650/5
Lutensol FA 5K
Mazeen C 2
Mazeen C 5
Nissan Nymeen F 215
Noramox C
Noramox C 11
Noramox C 2
Nymeen F 215
Optamine PC 5
PPEM 239
Rhodameen C5
Rofamin KD 3
Surfonic C 2
Variquat 1215
Varonic K 202
Varonic K 205
Varonic K 205LC
Varonic K 209
Varonic K 210
Varonic K 210LC
Varonic K 215
Varonic K 215LC
Witcamine 302
Witcamine 305



















VASELINE

Vaseline is a popular brand of petroleum jelly, known for its versatile and soothing properties.
Vaseline is a semi-solid, translucent substance with a smooth texture and no color or odor.
Vaseline is derived from petroleum or mineral oil and consists of a mixture of hydrocarbons and waxes.

CAS Number: 8009-03-8
EC Number: 232-373-2



APPLICATIONS


Vaseline is widely used as a skin moisturizer, providing relief for dry and chapped skin on various body parts.
Vaseline is a common ingredient in lip balms and chapsticks, soothing and protecting dry, chapped lips.

Vaseline is applied to minor cuts and burns to create a protective barrier that aids in the healing process.
In diaper rash prevention, it forms a protective layer on a baby's skin, reducing irritation from wetness and friction.
As a makeup remover, Vaseline gently dissolves and removes stubborn makeup without drying out the skin.

Vaseline is used as a lubricant for household items such as hinges, locks, and small mechanical parts.
Vaseline is applied to exposed skin in cold weather to protect against wind and cold temperatures.
For tattoo aftercare, Vaseline moisturizes and protects the skin as it heals after getting a tattoo.
In leather care, Vaseline is used to polish and protect leather products, like shoes and handbags, giving them a glossy finish.

Vaseline is a common ingredient in certain medical devices, such as oxygen masks, to prevent skin irritation and chafing.
Vaseline is used to protect and moisturize dry, cracked heels and feet.
Vaseline can be applied to areas prone to friction, such as thighs or underarms, to prevent chafing and irritation.

Some people use Vaseline to moisturize and condition their cuticles and nails.
Vaseline can be used to soothe minor burns and skin irritations caused by sunburn or windburn.
Vaseline is applied to the skin before applying self-tanning products to prevent uneven coloration.
As a hair care product, Vaseline is occasionally used to add shine and control frizz, but should be used sparingly to avoid greasiness.

In cold weather, Vaseline is applied to the nose and cheeks to protect against windburn and dryness.
Vaseline is used as a barrier cream for various industrial and household applications to protect the skin from contact with harsh chemicals.

Vaseline can be used to shine and protect leather shoes and other leather products.
Vaseline is included in first aid kits for its wound-healing properties and as a barrier against moisture and infection.
Vaseline is applied to the skin before applying certain types of body art or temporary tattoos to make their removal easier.

Some people use Vaseline to moisturize and condition eyelashes, potentially improving their appearance.
Vaseline is occasionally used as a lubricant for bike chains and gears, but care should be taken not to attract dust and debris.

Vaseline can be used to protect and moisturize the skin during and after outdoor activities, such as hiking and camping.
Some individuals use Vaseline as a base for homemade skincare products, including DIY lip balms and body lotions.
Vaseline is used as a barrier cream in professions where the skin comes in contact with chemicals or irritants, such as hairdressing and mechanics.

Vaseline can be applied to the skin before hair dyeing to create a protective barrier and prevent staining on the scalp and hairline.
Vaseline is used as a lubricant for various mechanical and household tasks, such as unsticking zippers and lubricating small moving parts.
Vaseline is sometimes applied to the inner thigh area to prevent chafing during activities like running or cycling.

As a skin protectant, Vaseline is used by swimmers to create a barrier against chlorine and saltwater exposure.
Vaseline can be applied to minor burns, such as those caused by cooking accidents, to provide relief and aid in the healing process.

Vaseline is used by some athletes to prevent blisters and chafing on areas prone to friction during sports activities.
Vaseline can be used to protect and moisturize the skin around the nails before applying nail polish.

In the beauty industry, Vaseline is occasionally used to create a glossy finish on eyelids and lips for a dewy makeup look.
Vaseline can be applied to dry and cracked elbows and knees to soften and moisturize the skin.

Vaseline is sometimes used in theater and special effects makeup to create simulated wounds and scars.
Vaseline is applied to the edges of a paper stencil when painting or airbrushing to prevent paint bleeding and ensure sharp lines.

In DIY projects, Vaseline can be used as a release agent to prevent sticking when casting molds or working with epoxy resin.
Vaseline can be applied to the skin before applying temporary tattoos or henna to facilitate easy removal.
Vaseline is used by some runners and athletes to protect and moisturize their feet before long-distance races.

As a pet care product, Vaseline is occasionally used to moisturize dry and cracked paw pads on dogs and cats.
Vaseline is applied to the skin before handling strong-smelling substances to create a barrier and reduce odor absorption.
Vaseline can be used as a highlighter on the high points of the face for a natural glow in makeup application.
Vaseline can be applied to the skin before using hair removal creams to create a barrier and prevent irritation.

As a grooming aid, it is used to tame and shape eyebrows and keep stray hairs in place.
Vaseline is sometimes used in the process of mold-making for sculptures and other artworks.

Vaseline can be used to remove adhesive residues left by stickers and labels on various surfaces.
Vaseline is occasionally applied to the inside of gloves to make them easier to put on and remove.

As a travel essential, it can be used to prevent liquid toiletries from leaking during flights or trips.
Vaseline is used by some people to polish and condition leather furniture to maintain its appearance and texture.


Vaseline, or petroleum jelly, has a wide range of applications due to its versatile and soothing properties.
Here are some of its common applications:

Skin Moisturizer:
Vaseline is widely used as a skin moisturizer to alleviate dry and chapped skin on various body parts, including hands, feet, and elbows.

Lip Balm:
Vaseline is a popular ingredient in lip balms and chapsticks, providing relief and protection for dry, chapped lips.

Wound Care:
Vaseline can be applied to minor cuts, scrapes, and burns to create a protective layer that aids in the healing process and reduces the risk of infection.

Diaper Rash Prevention:
It is used in diaper rash prevention to create a protective barrier on a baby's skin, helping to prevent irritation from wetness and friction.

Makeup Remover:
Vaseline is an effective and gentle makeup remover, dissolving and removing makeup without drying out the skin.

Lubricant:
It can be used as a lubricant for various household items, such as hinges, locks, and small mechanical parts.

Hair Care:
Some people use Vaseline to add shine and control frizz in their hair, but it should be used sparingly to avoid greasiness.

Cold Weather Protection:
Vaseline can be applied to exposed skin in cold weather to provide a protective barrier against wind and cold temperatures.

Tattoo Aftercare:
Vaseline is used in tattoo aftercare to protect and moisturize the skin as it heals after getting a tattoo.

Leather Care:
Vaseline is used to polish leather products, such as shoes and handbags, to give them a shiny finish.

Medical Devices:
Vaseline is a common ingredient in certain medical devices, like oxygen masks, to prevent skin irritation and chafing.

Foot Care:
Vaseline is used to protect and moisturize dry, cracked heels and feet.

Friction Protection:
Vaseline can be applied to areas prone to chafing and friction, such as thighs or underarms, to prevent irritation.

Nail Care:
Some people use Vaseline to moisturize and condition their cuticles and nails.

Eyelash Care:
Vaseline is occasionally used to moisturize and condition eyelashes.

Sunburn Relief:
Vaseline can be used to soothe minor burns and skin irritations caused by sunburn or windburn.

Minor Burns:
Vaseline is used to provide relief for minor burns by creating a protective barrier on the affected skin.

Leather Shoes:
Vaseline can be used to shine and protect leather shoes.

First Aid Kit:
Vaseline is a common addition to first aid kits for its wound-healing properties.

Bike Maintenance:
Vaseline is occasionally used as a lubricant for bike chains and gears.



DESCRIPTION


Vaseline is a popular brand of petroleum jelly, known for its versatile and soothing properties.
Vaseline is a semi-solid, translucent substance with a smooth texture and no color or odor.
Vaseline is derived from petroleum or mineral oil and consists of a mixture of hydrocarbons and waxes.
Due to its occlusive nature, Vaseline forms a protective barrier on the skin, retaining moisture and preventing dryness.

Vaseline is widely used as a skin moisturizer to alleviate dry and chapped skin on various body parts.
Vaseline is a non-comedogenic substance, making it suitable for all skin types without clogging pores.

Vaseline is commonly found in lip balms and chapsticks, providing relief and protection for dry, chapped lips.
Vaseline is often used in wound care to create a protective layer over minor cuts and burns, aiding in the healing process.
Vaseline can be applied to protect and soothe skin from irritants and friction, making it useful in diaper rash prevention.
Vaseline has a long shelf life and does not spoil easily, making it a reliable skincare product.

Vaseline is widely available and cost-effective, making it a popular choice for everyday skincare needs.
Vaseline is a common ingredient in various cosmetic and skincare products, such as creams, lotions, and ointments.

The gentle and non-irritating properties of Vaseline make it suitable for sensitive skin and can be used on infants and children.
Vaseline is used by some people to help soothe minor burns and skin irritations caused by sunburn or windburn.
Vaseline is an effective makeup remover, gently dissolving and removing stubborn makeup without drying out the skin.

Vaseline can be used as a lubricant for household items like hinges, locks, and small mechanical parts.
Vaseline is sometimes used to add shine and control frizz in hair, though it should be applied sparingly to avoid greasiness.
Vaseline is often applied to exposed skin in cold weather to provide a protective barrier against the elements.

Some individuals use Vaseline to polish leather products, such as shoes and handbags, for a shiny finish.
In tattoo aftercare, Vaseline is used to protect and moisturize the skin as it heals.
Vaseline is a common ingredient in certain medical devices, like oxygen masks, to prevent skin irritation and chafing.

Vaseline is occasionally used as a base for homemade skincare products, such as DIY lip balms and body lotions.
Vaseline is known for its hypoallergenic properties, making it suitable for those with allergies or sensitivities.

Some people use Vaseline to protect and moisturize dry, cracked heels and feet.
The ease of application and the absence of strong fragrances make Vaseline a go-to product for basic skincare needs.



PROPERTIES


Physical Properties:

Appearance: Semi-solid, translucent substance
Texture: Smooth and waxy
Color: Colorless or pale yellow
Odor: Odorless
Melting Point: Approximately 37°C (98.6°F)
Boiling Point: Above 200°C (392°F) (Vaseline does not have a precise boiling point as it gradually softens and evaporates when heated.)


Chemical Properties:

Chemical Formula: Complex mixture of hydrocarbons and waxes
Composition: Mainly composed of carbon and hydrogen atoms
Chemical Stability: Stable under normal conditions
Flammability: Vaseline is combustible and may catch fire if exposed to an open flame or heat source.



FIRST AID


Inhalation:

If Vaseline is accidentally inhaled and respiratory symptoms occur, move the affected person to fresh air immediately.
If the person is having difficulty breathing, provide artificial respiration if trained to do so and seek immediate medical attention.
Keep the affected person calm and at rest while awaiting medical assistance.


Skin Contact:

If Vaseline comes into contact with the skin, promptly remove contaminated clothing and wash the affected area with mild soap and water.
Avoid using harsh chemicals or solvents for cleaning, as they may irritate the skin further.
If skin irritation, redness, or rash persists, seek medical attention for further evaluation and treatment.


Eye Contact:

If Vaseline accidentally gets into the eyes, immediately flush the eyes with clean water for at least 15 minutes while holding the eyelids open to ensure thorough rinsing.
Remove contact lenses, if present and easy to do so, after the initial rinse.
Seek immediate medical attention or contact a poison control center for further guidance.


Ingestion:

In case of accidental ingestion of Vaseline, do NOT induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth gently with water if the person is conscious and not showing signs of aspiration.
Seek immediate medical attention or contact a poison control center for further guidance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Vaseline in large quantities or during industrial processes, wear appropriate personal protective equipment (PPE) such as chemical-resistant gloves and safety goggles or a face shield to prevent direct skin and eye contact.

Avoid Contact with Eyes and Ingestion:
Avoid contact with eyes.
In case of accidental eye contact, flush the eyes with clean water for at least 15 minutes and seek immediate medical attention.
Do NOT ingest Vaseline.
If accidentally ingested, seek immediate medical attention or contact a poison control center.

Ventilation:
Use Vaseline in a well-ventilated area to prevent the buildup of vapors.
Ensure adequate ventilation during storage, handling, and application.

Storage of Vaseline Containers:
Store Vaseline containers in a cool, dry place, away from direct sunlight and heat sources.
Keep them tightly closed when not in use to prevent evaporation and contamination.
Store Vaseline away from open flames, sparks, and potential sources of ignition, as it is combustible.

Prevent Cross-Contamination:
Avoid cross-contamination by using clean and dry tools or dispensers when handling Vaseline to prevent introducing impurities.

Use Non-Sparking Tools:
If handling Vaseline in industrial settings, use non-sparking tools and equipment to minimize the risk of fire and explosions.

Prevent Skin Irritation:
Apply Vaseline to intact skin only and avoid using it on open wounds or broken skin to prevent potential irritation.

Wash Hands:
After handling Vaseline, wash hands thoroughly with soap and water to remove any residue.


Storage:

Temperature:
Store Vaseline in a cool and dry area with temperatures between 15°C to 25°C (59°F to 77°F).
Avoid exposure to extreme temperatures, as excessive heat may cause the product to melt or separate.

Keep Containers Sealed:
Keep Vaseline containers tightly closed when not in use to prevent contamination and evaporation.

Storage Area:
Designate a specific storage area for Vaseline to avoid accidental mixing with other substances.

Segregation:
Store Vaseline away from strong oxidizing agents and acids to prevent potential chemical reactions.

Accessibility:
Ensure that the storage area is accessible only to authorized personnel and kept secure.

Compatibility:
Use containers made of materials compatible with Vaseline, such as plastic, glass, or metal.

Environmental Considerations:
Observe all local environmental regulations when storing Vaseline to prevent environmental contamination.



SYNONYMS


Petroleum jelly
Petrolatum
White petrolatum
Soft paraffin
Paraffinum liquidum
Liquid paraffin
Mineral jelly
Multi-hydrocarbon
Adepsine oil
Petrolatum album
Glycerine jelly
Liquid vaseline
Unctuous petrolatum
White wax
Paraffin oil
Paraffin wax
Mineral grease
Ozokerite
White wax jelly
Wool wax
Adepsine jelly
Soft Vaseline
Adepsine
Paraffin jelly
Paraffinum album
Petrolatum album
Soft paraffin
Adepsine oil
Multi-hydrocarbon
Yellow petrolatum
White wax
Hydrocarbon gel
Lubricating jelly
Liquid petrolatum
Ozokerite wax
Unctuous petrolatum
Wool fat
Jelly vaseline
Ozokerite jelly
Paraffinum liquidum
Adeps solidus
Paraffinum subliquidum
White petroleum jelly
Yellow petroleum jelly
Solid paraffin
Soft paraffin wax
Paraffin gel
Soft vaseline
Yellow wax
Liquid wax
Mineral jelly
Multi-hydrocarbon
Adepsine oil
Petrolatum album
Glycerine jelly
Liquid vaseline
Unctuous petrolatum
White wax
Paraffin oil
Paraffin wax
Mineral grease
Ozokerite
White wax jelly
VASELINE PHARMA GRADE
Vaseline pharma grade is a pale yellow to yellow-colored, translucent, soft unctuous mass.
Vaseline pharma grade is odorless, tasteless, and not more than slightly fluorescent by daylight, even when melted.
White or Yellow Vaseline pharma grade is made by the waxy petroleum material which formed on oil rigs and distilling it.

CAS Number: 8009-03-8
Molecular Formula: C15H15N
Molecular Weight: 209.2863
EINECS Number: 232-373-2

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Vaseline pharma grade is odourless, tasteless, homogenous mixture of long chain oil & waxy hydrocarbons.
Vaseline pharma grade possess highest degree of purity.
Vaseline pharma grade, cosmetics and industrial grade is the name of a popular brand of petroleum jelly, It is a mixture of mineral oils and waxes that are easily spreadable.

The lighter and thinner oil-based products make up Vaseline pharma grade jelly, also known as white petrolatum or simply as petrolatum.
Vaseline pharma grade, is a semi-solid mixture of hydrocarbons, having a melting point usually in the range of 25 to 30 degrees Celsius (77 to 86 degrees Fahrenheit).
Pharma-grade Vaseline pharma grade is a purified and refined form of petroleum jelly that meets the standards and requirements for use in pharmaceutical and medical applications.

Vaseline pharma grade is used in cosmetics ,medical, industrial due to the healing properties of Vaseline pharma grade.
Vaseline pharma grade is the malthenes purified from lubrication oil, the mixture of residue oil and cerate.
Vaseline pharma grade is an important lubricant for medicines, cosmetics, fine chemical raw materials and precision instruments.

In China, major Vaseline pharma grades include ordinary vaseline, industrial vaseline and medical vaseline.
Ordinary vaseline is suitable for the preparation of various ointments and softener of dark rubber products; industrial vaseline can be used to protect metal products and general machinery parts against rust and lubricate machines under light loads, but also can be used as treating compound for leather and rubber softener.
Vaseline pharma grade products are mainly concentrated in the medicinal Vaseline, which is divided into two: medical white vaseline and medical yellow Vaseline.

Medical Vaseline pharma grade is mainly used in the preparation of ointment, skin protection cream and cosmetics raw materials, as well as antirust and lubricating materials for medical instruments and precision instruments.
White or yellow homogeneous paste, almost odorless and tasteless, a mixture of liquid and solid paraffin hydrocarbons.

Vaseline pharma grade is easy to dissolve in ethyl ether, petroleum ether, fatty oil, benzene, carbon disulfide, chloroform and turpentine, difficult to dissolve in ethanol and almost insoluble in water.
Vaseline pharma grade is heated into a transparent liquid, which can be fluorescent in the dark after ultraviolet radiation.
Vaseline pharma grade is a complex combination of hydrocarbons obtained as a semi-solid from dewaxing paraffinic residual oil.

Vaseline pharma grade consists predominantly of saturated crystalline and liquid hydrocarbons having carbon numbers predominantly greater than C25.
Vaseline pharma grade is mainly used in topical pharmaceutical formulations as an emollient-ointment base; it is poorly absorbed by the skin.
Vaseline pharma grade is also used in creams and transdermal formulations and as an ingredient in lubricant formulations for medicated confectionery together with mineral oil.

Therapeutically, sterile gauze dressings containing petrolatum may be used for nonadherent wound dressings or as a packing material.
Vaseline pharma grade is additionally widely used in cosmetics and in some food applications.
Vaseline pharma grade, petrolatum, white petrolatum, soft paraffin, or multi-hydrocarbon, CAS number 8009-03-8, is a semi-solid mixture of hydrocarbons (with carbon numbers mainly higher than 25), originally promoted as a topical ointment for its healing properties.

Vaseline pharma grade has been an American brand of petroleum jelly since 1870.
Vaseline pharma grade jelly became a medicine-chest staple, consumers began to use it for cosmetic purposes and for many ailments including toenail fungus, genital rashes (non-STI), nosebleeds, diaper rash, and common colds.
Vaseline pharma grade is folkloric medicinal value as a "cure-all" has since been limited by a better scientific understanding of appropriate and inappropriate uses.

Vaseline pharma grade is recognized by the U.S. Food and Drug Administration (FDA) as an approved over-the-counter (OTC) skin protectant and remains widely used in cosmetic skin care, where it is often loosely referred to as mineral oil.
Vaseline pharma grade is a mixture of natural waxes and mineral oils that together lock moisture in the skin, moisturizing it to repair and relieve dryness.
Vaseline pharma grade is made by the waxy petroleum material that formed on oil rigs and distilling it.

Vaseline pharma grade has been used in various ointments and as a lubricant. The history of vaseline starts in 1859.
That s where oil workers had been using rod wax, an unrefined form of Vaseline pharma grade then just a simple by-product of the drilling they were working on to heal wounded or burnt skin.
Vaseline pharma grade is used all over the world to protect and heal dry skin, from dry, cracked hands to hard skin on heels, as well as for beauty purposes, like softening the lips or highlighting the cheekbones.

Vaseline pharma grade is used to protect and repair the skin.
Vaseline pharma grade is used for preventing diaper rash, but it can also be used to protect minor cuts and burns, to soften skin, and to lock in moisture in dry, cracked skin.
Vaseline pharma grade is manufactured using highly refined paraffinic white mineral oils and waxes.

This ensures the products are as per the pharmacopeia requirements.
Various grades of Vaseline pharma grade Jellies catering to Pharma & personal care products as well as technical grades for less critical applications and meeting specifications of customers are manufactured.
Vaseline pharma grade’s complies the requirements of pharmacopeia (IP, USP& BP) and is manufactured as per the GMP norms.

Vaseline pharma grade, cosmetics and industrial grade is a mixture of hydrocarbons with a melting point that depends on the exact proportion.
In case the melting point is typically between 40 and 70 C ( 105 and 160 F), In other words Vaseline is flammable only when heated to liquid; then the fumes, not the liquid itself, will burn, so a wick material such as leaves, bark or small twigs is required to ignite the vaseline.
As well as vaseline colorless(or pale yellow when not highly distilled), translucent and devoid of taste and odor when pure.

Vaseline pharma grade doesn’t oxidize when exposed to air and it not immediately affected by chemical reagents.
Vaseline pharma grade insoluble in water, And also It is soluble in dichloromethane, chloroform, benzene, diethyl ether, carbon disulfide and turpentine.
Vaseline pharma grade jelly acts as a plasticizer on polypropylene (PP) , but is compatible with most other plastic ( citations needed).

Due to Vaseline pharma grade is semi-solid, it keeps its shape forever like a solid substance, but although it does not flow by itself, it can be forced to take the shape of the container it is in without breaking down lol a liquid.
Vaseline pharma grade, cosmetics and industrial grade is a white, yellow or light amber colored semi-solid oily substance.
Vaseline pharma grade’s transparent when thin layered, slightly fluorescent.

Vaseline pharma grade is insoluble in water , almost insoluble in cold or hot ethanol and cold anhydrous ethanol.
Vaseline pharma grade soluble in ether, hexane and most volatile or non-volatile oil; it’s readily soluble in benzene, carbon disulfide, chloroform and turpentine.
Vaseline pharma grade is made by the waxy petroleum material that formed on oil rigs and distilling it.

Vaseline pharma grade consists predominantly of saturated crystalline and liquid hydrocarbons having carbon numbers predominantly greater than C25.
The lighter and thinner oil-based products make up Vaseline also known as white petrolatum, no smell, or simpleton as petroleum ,which a semisolid jelly-like substance.
Vaseline pharma grade is obtained from the purification of heavy petroleum oils, which is the residue of distillation at 360 degree shear.

Vaseline pharma grade is a mixture of hydrocarbons, with a melting point that depends on the exact proportions.
The melting point is typically between 40 and 70 °C (105 and 160 °F).
Vaseline pharma grade is flammable only when heated to liquid; then the fumes will light, not the liquid itself, so a wick material is needed to ignite petroleum jelly.

Vaseline pharma grade is colorless (or of a pale yellow color when not highly distilled), translucent, and devoid of taste and smell when pure.
Vaseline pharma grade does not oxidize on exposure to the air and is not readily acted on by chemical reagents.
Vaseline pharma grade is insoluble in water.

Vaseline pharma grade is soluble in dichloromethane, chloroform, benzene, diethyl ether, carbon disulfide and turpentine.
Vaseline pharma grade is slightly soluble in alcohol.
Vaseline pharma grade acts as a plasticizer on polypropylene (PP), but is compatible with most other plastics.

Vaseline pharma grade is a semi-solid, in that it holds its shape indefinitely like a solid, but it can be forced to take the shape of its container without breaking apart, like a liquid, though it does not flow on its own.
Depending on the specific application of petroleum jelly, it may be USP, B.P., or Ph. Eur. grade.
This pertains to the processing and handling of the Vaseline pharma grade so it is suitable for medicinal and personal-care applications.

Petroleum Jelly or Vaseline would be a white jelly-like (Paste) substance that is a combination of heavy hydrocarbons (more than 25) produced by the distillation of petroleum products and petroleum oils.
The chemical formula of Vaseline pharma grade is C25H52 which is also called Petrolatum and Vaseline.
Vaseline pharma grade under the brand name Vaseline is a derivative of crude oil, which is obtained during the distillation process of heavy crude oil, in order to produce pharmaceutical and health grades, it is completely refined and should be removed from waste materials completely.

The cosmetic and pharmaceutical grade (Pharma Grade) of Vaseline pharma grade is completely white and odorless.
Vaseline pharma grade is made up of pure petroleum jelly which contain minerals and micro crystalline wax so it is smoother.
Vaseline pharma grade, is used as the basis for making cosmetics.

Vaseline pharma grade not only, hurt the body skin, but also make it fresh and help to skin hydrotherapy.
Vaseline pharma grade has been around since 1872.
More common names for this material are petroleum jelly or Vaseline pharma grade (a registered trademark of Unilever).

Vaseline pharma grade has evolved from a relatively impure waxy substance to the highly refined product that we know today.
Vaseline pharma grade is used in hundreds of different applications that range from shoe polish to dielectric lubricants to drugs and cosmetics.
This paper concerns the use of highly refined Vaseline pharma grade in food, drug and cosmetic applications.

Vaseline pharma grade in drug products and the obligations manufacturers have when selling petrolatum into the drug market.
Removal of impurities, contaminants, and unwanted Vaseline pharma grade to achieve a higher level of purity.
Ensuring the Vaseline pharma grade is free from microbial contamination.

Regular testing and quality assurance measures to meet pharmacopeial standards.
Vaseline pharma grade is commonly used in various pharmaceutical and medical applications, including as a skin protectant, ointment base, or lubricant.
Vaseline pharma grade provides a barrier on the skin to lock in moisture and is often used for conditions such as dry skin, chapped lips, and minor cuts or burns.

Vaseline pharma grade is often used as a protective barrier for the skin.
Vaseline pharma grade helps prevent moisture loss and protects the skin from environmental factors such as wind and cold weather.
Vaseline pharma grade is applied to minor cuts, scrapes, and burns to create a protective barrier that aids in the natural healing process and reduces the risk of infection.

Vaseline pharma grade is used to alleviate symptoms of dry skin conditions, such as eczema and psoriasis.
Vaseline pharma grade helps to lock in moisture and soothe irritated skin.
Vaseline pharma grade is a common ingredient in lip balms and ointments for treating and preventing chapped lips.

In certain medical procedures, Vaseline pharma grade is used as a lubricant for catheters and other medical instruments to facilitate insertion.
Vaseline pharma grade can be incorporated into barrier creams used in healthcare settings to protect the skin from irritants and bodily fluids.

In addition to its medical uses, Vaseline pharma grade is also used in cosmetic products such as creams, lotions, and makeup products to provide moisturization and skin protection.
Vaseline pharma grade serves as a base for various pharmaceutical formulations, including ointments and creams, where its emollient properties are beneficial.

Melting point: 70-80 °C ((ASTM D 127))
Boiling point: 322 °C
Density: 0.84
refractive index: n20/D 1.45
Flash point: 198 °C
storage temp.: Sealed in dry,Room Temperature
solubility: Practically insoluble in acetone, ethanol, hot or cold ethanol (95%), glycerin, and water; soluble in benzene, carbon disulfide, chloroform, ether, hexane, and most fixed and volatile oils.
form: extra-low viscosity oil
Specific Gravity: 0.815~0.880 (60℃)
color: white
PH: pH (25℃) : 4.5~8.0

Vaseline pharma grade is thick substance known as petrolatum or Vaseline (a brand name), is a semi-solid mixture of hydrocarbons, having a smooth texture and a high melting point and made from petroleum, a naturally occurring substance that is obtained from crude oil.
Vaseline pharma grade is colorless or slightly yellowish and is odorless.
Vaseline pharma grade has a wide range of applications due to its unique properties.

Vaseline pharma grade a white, yellow or light amber semisolid fatty substance.
Transparent when thin-layered, slightly fluorescent.
Insoluble in water, almost insoluble in cold or hot ethanol and cold anhydrous ethanol.

Soluble in ether, hexane and most volatile or non-volatile oil; easily soluble in benzene, carbon disulfide, chloroform and turpentine.
Vaseline pharma grade is commonly used as a moisturizer and protectant for the skin.
Vaseline pharma grade forms a barrier on the skin, helping to lock in moisture and protect it from drying out, making it useful for dry or chapped skin, as well as for soothing minor cuts, burns, and irritations.

Vaseline pharma grade is also used in cosmetic products such as lip balms, lotions, and creams.
Vaseline pharma grade has been widely used for over a century and is considered safe for most people when used as directed.
However, Vaseline pharma grade is important to follow instructions and avoid using it on broken or infected skin, as well as to be aware of any potential allergies or sensitivities.

This is the most common grade of jelly and is widely used in cosmetic and personal care products.
Vaseline pharma grade is highly refined and purified to remove impurities, color, and odor, resulting in a white or off-white color.
Vaseline pharma grade is typically used for skin moisturization, lip balms, and other cosmetic applications.

Vaseline pharma grade, or Medical Vaseline is a semi-solid combination of hydrocarbons (with carbon numbers mostly greater than 25), which was first advertised as a topical treatment for its curative effects.
A combination of hydrocarbons that is Vaseline pharma grade of the pharmaceutical grade has a melting point that is often just a few degrees above the average human body temperature, or around 37 °C (99 °F).
Vaseline pharma grade, cosmetics and industrial grade sold in different forms and packages in the market, whether it is pure or in combination with additives in the form of lotion, ointment, cream, or solid, it is produced by different companies.

Vaseline pharma grade is packaging will be different and depends mostly on its use in health and cosmetic purposes.
Vaseline pharma grade is manufactured from blends of waxes and pure oils. Because of their purity they are widely used as base for ointments, salves, veterinary and cosmetic applications.
They are also used extensively in food processing, plastics, rubber, tobacco, paper and rope industries. Complies USP, BP, EP requirements.

Vaseline pharma grade is less refined than white petroleum jelly and may contain some impurities, resulting in a yellowish color.
Yellow petroleum jelly is commonly used in industrial applications, such as as a lubricant for machinery, rust prevention, and protection of metal surfaces.
Vaseline pharma grade of PJ is highly purified and meets specific standards for use in medical and pharmaceutical applications.

Vaseline pharma grade is often used as a lubricant for medical equipment, as an ingredient in medicinal products, and for wound care.
Vaseline pharma grade is a mixture of hydrocarbons which is semisolid at room teprature, and it is also odorless, when properly refined.
Vaseline pharma grade is used in a variety of industries, also known as petrolatum or soft paraffin.

Vaseline pharma grades can be used as excipients and as active pharmaceutical ingredients.
Their protective, healing, moisturising and soothing properties are highly valued by the pharmaceutical and cosmetic industries.
Vaseline pharma grade is a mixture of mineral oils and waxes, which form a semisolid jelly-like substance.

Vaseline pharma grade’s benefits come from its main ingredient petroleum, which helps seal your skin with a water-protective barrier.
This helps skin heal and retain moisture.
Vaseline pharma grade heals minor skin scrapes and burns, moisturizes face and hands, prevents diaper rashes, removes eye makeup, it can reduce the look of split ends and add shine to your hair, and preserves perfume scents.

Cosmetic grade Vaseline pharma grade has very well property for curing dry skin and protect it and made it humid, also cosmetic petroleum jelly or Vaseline is used for curing lips and face skin, so it is used as the basis for making cosmetics.
Vaseline pharma grade is one the most reputable and best seller product all over the world.
This question is not being asked from a technical point of view, but rather from a regulatory perspective.

Vaseline pharma grade with CAS number 8009-03-8 has the following definition.
Vaseline pharma grade is also known as Mineral Jelly or Petrolatum.
Vaseline pharma grade is mostly used in emulsion form in cosmetics & pharmaceutical for the preparations of various creams, ointments, lotions etc.

Vaseline pharma grade is used in the manufacturing of lubricants & Grease.
Vaseline pharma grade of good quality is used in Vaseline manufacturing.
Vaseline pharma grade is also used as a moisturizer in good quality toilet soaps.

Vaseline pharma grade also finds its use as an anti-rusting agent for iron goods like blade, wire surgical instruments etc.
Vaseline pharma grade, white petrolatum, soft paraffin/paraffin wax or multihydrocarbon, is a semi-solid mixture of hydrocarbons (with carbon numbers mainly higher than 25), originally promoted as a topical ointment for its healing properties.
Vaseline pharma grade is odorless and colorless and it has an inherently long shelf life.

These qualities make Vaseline pharma grade a popular ingredient in skincare products and cosmetics.
With highly refined hydrocarbons Vaseline pharma grades used in Pharmaceutical, Veterinary and Personal Care applications.
Vaseline pharma grades are used in a wide variety of applications in the rubber, automotive and other industrial segments.

Vaseline pharma grade undergoes stringent quality control measures to ensure its purity.
Vaseline pharma grade is refined and purified to meet the standards set by regulatory authorities for pharmaceutical and medical use.
Vaseline pharma grade often complies with pharmacopeial standards, such as the United States Pharmacopeia (USP) or the European Pharmacopoeia (Ph. Eur.), which define the quality and purity requirements for pharmaceutical substances.

To meet pharmaceutical standards, Vaseline pharma grade used in medical applications is usually free from unnecessary additives, fragrances, or colors.
This reduces the risk of skin irritation and makes it suitable for sensitive skin.
Vaseline pharma grade is designed to be hypoallergenic, minimizing the risk of allergic reactions.

This is especially important in medical applications where skin sensitivity is a concern.
The manufacturing process for Vaseline pharma grade aims to produce a product with consistent properties, ensuring that each batch meets the required specifications for medical and pharmaceutical applications.
The packaging of Vaseline pharma grade is often designed to maintain sterility and prevent contamination.

Vaseline pharma grade may come in tubes, jars, or other containers suitable for medical use.
Depending on the region and specific use, Vaseline pharma grade may be subject to regulatory approval by health authorities.
Vaseline pharma grade this ensures that the product meets the necessary safety and efficacy standards.

Many pharmaceutical-grade skin care products, including Vaseline pharma grade, undergo dermatological testing to confirm their safety and suitability for use on various skin types, including sensitive or compromised skin.
Vaseline pharma grade is commonly used in various medical applications.
Vaseline pharma grade serves as a skin protectant and emollient, helping to soothe and protect the skin.

Vaseline pharma grade is often recommended for conditions such as dry skin, chapped lips, and minor skin irritations.
In some cases, Vaseline pharma grade is used in wound care. It can be applied to wounds or incisions to create a barrier that helps prevent infection and promotes the healing process.
However, specific uses may vary based on healthcare provider recommendations.

Dermatologists may recommend pharmaceutical-grade Vaseline as part of formulations for skin conditions such as eczema or dermatitis.
Vaseline pharma grade is emollient properties can contribute to moisturizing and protecting the skin.
Vaseline pharma grade is often considered safe for use on infants and children. It can be applied to diaper rash or other minor skin irritations.

However, Vaseline pharma grade's essential to follow pediatrician recommendations for specific applications.
Vaseline pharma grade's inert nature makes it compatible with various medications and treatments.
Vaseline pharma grade can be used in conjunction with other topical medications or as a protective layer over certain skin treatments.

In the field of tattooing, pharmaceutical-grade Vaseline is sometimes recommended for tattoo aftercare.
Vaseline pharma grade can be applied to freshly tattooed skin to keep it moisturized and aid in the healing process.
Vaseline pharma grade is often formulated to be non-comedogenic, meaning it is less likely to clog pores.

This makes Vaseline pharma grade suitable for use on the face and body without causing acne or exacerbating skin conditions.
Beyond medical and cosmetic applications, Vaseline pharma grade may have uses in laboratory settings or certain industrial processes where a lubricating or protective substance is required.
Vaseline pharma grade is widely available globally, and different brands may offer variations of the product.

Vaseline pharma grade's important to choose a reputable brand that adheres to pharmaceutical standards.
Ongoing research and development may lead to innovations in Vaseline pharma grade formulations, potentially introducing new features or benefits for specific medical or cosmetic needs.

Production:
Acid-carclazyte method is a traditional method for the production of Vaseline pharma grade, which is still in use at home and abroad.
In the process, add sulfuric acid with more than 98% concentration measured up to about 60% of raw materials and mix it with the raw material in the reactor.
The reaction temperature is kept at 70℃.

After the reaction, the acid residue is separated and diluted with alcohol to further remove the acid residue.
The oil treated with acid in another clay refining tank is decolorized with carclazyte at about 140℃, and then filtered to obtain the final product.

The characteristics of the acid-carclazyte method: the high-quality parts can be produced, PAHs can reach the level of pharmaceutical grade and other relevant indicators can meet the quality index of the pharmacopoeia, which is the reason of traditional craft’s long time existence.
The main disadvantage of the method is too low goal product yield (about 50%) and a large number of acid residues which is difficult to be utilized resulting in serious environmental pollution and very high production cost.

Aluminum chloride method has taken place of acid-carclazyte method to produce vaseline from 60s at home.
The process is as follows: the raw material reacts with aluminum chloride after dehydration in the reactor, reaction temperature is between 130℃ to 140℃.
After the reaction, the oil will be neutralized and precipitated with alkali liquor in the neutralization tank.

Then remove the slag and refine by carclazyte adsorption in the decolorizing tank.
Vaseline pharma grade is obtained by filtering refined oil at about 120℃.
The yield of aluminum chloride method is higher than that of acid-carclazyte method, and consumption index seems lower, but the quality is slightly worse; compared with vaseline produced by medium-pressure hydrocracking and high pressure hydrogenation was there is a great gap in color, transparency, the content of polycyclic aromatic hydrocarbons and so on.

Hydrogenation method is a new process for the production of vaseline, which is usually carried out with 10, 20, or 30MPa and lower liquid hourly space velocity.
The process is to convert the useless components in the raw materials into effective components, so that the product yield can be nearly 100%.
But aluminum chloride method or acid-carclazyte method changes useless components into waste slags to dump containing effective components, which reduces the product yield.

Due to the product yield, the refining extent of luminum chloride method or acid-carclazyte method is also limited, thus limiting the further improvement of product quality.
So the hydrogenation method is better than aluminum chloride method and acid-carclazyte method both in product yield or quality.
Vaseline pharma grade is manufactured from the semisolid residue that remains after the steam or vacuum distillation of petroleum.

This residue is dewaxed and/or blended with stock from other sources, along with lighter fractions, to give a product with the desired consistency.
Final purification is performed by a combination of high-pressure hydrogenation or sulfuric acid treatment followed by filtration through adsorbents.
A suitable antioxidant may be added.

Pharmaceutical Vaseline pharma grade is semi solid mixture of hydrocarbons with specially selected waxes, forming ointment like gels, which are nearly odorless with excellent hydrating characteristics.
It is made by the waxy petroleum material that formed on oil rigs and distilling it.
Pharmaceutical Vaseline pharma grade is favored by personal care and pharmaceutical companies as very versatile, safe and economical formulation base.

Vaseline pharma grade Supplied by HJ Oil Group is a mixture of highly refined and treated hydrocarbons, having odorless characteristics.
The product offered comply to National & International Standards and Pharmacopoeias such as IP, BP, USP & EP.
Vaseline pharma grade manufactured by HJ Oil Group is used as base for ointments, personal care, veterinary and other pharmaceutical, cosmetic and Industrial applications.

History:
Marco Polo in 1273 described the oil exportation of Baku oil by hundreds of camels and ships for burning and as an ointment for treating mange.
Native Americans discovered the use of petroleum jelly for protecting and healing skin.
Sophisticated oil pits had been built as early as 1415–1450 in Western Pennsylvania.

In 1859, workers operating the United States's first oil rigs noticed a paraffin-like material forming on rigs in the course of investigating malfunctions.
Believing the substance hastened healing, the workers used the jelly on cuts and burns.
Robert Chesebrough, a young chemist whose previous work of distilling fuel from the oil of sperm whales had been rendered obsolete by petroleum, went to Titusville, Pennsylvania, to see what new materials had commercial potential.

Chesebrough took the unrefined green-to-gold-colored "rod wax", as the drillers called it, back to his laboratory to refine it and explore potential uses.
He discovered that by distilling the lighter, thinner oil products from the rod wax, he could create a light-colored gel. Chesebrough patented the process of making Vaseline pharma grade by U.S. Patent 127,568 in 1872.
The process involved vacuum distillation of the crude material followed by filtration of the still residue through bone char.

Chesebrough traveled around New York demonstrating the product to encourage sales by burning his skin with acid or an open flame, then spreading the ointment on his injuries and showing his past injuries healed, he said, by his miracle product.
He opened his first factory in 1870 in Brooklyn using the name Vaseline.

Uses:
With the characteristics of no color or smell, chemical inertness, semisolid, lipophilic property and good adhesion, Vaseline pharma grade is suitable to manufacture substrates of hair cream, hair conditioner, eye cream, lipstick, wax matrix and so on.
Vaseline pharma grade can be widely used as the matrix of ointment because it is almost compatible with all drugs without changes in drugs.
Vaseline pharma grade can be prepared by adding alcohols such as stearyl alcohol, cetyl alcohol and cholesterol after heated fusion and sufficient stir.

Vaseline pharma grade is an ointment base with strong permeability, stability and small stimulation.
This ointment matrix can be used alone for dry skin rash, erythema, papules and other diseases, especially for the removal of blood scab and desquamation.
Vaseline pharma grade can also be used as a non-ionic emulsifier to be compatible with cholesterol, so the range of compatibility is very wide.

In addition, Vaseline pharma grade can be compatible with liquid drugs or aqueous solutions of drugs because of its absorbability.
Vaseline pharma grade can be used as rubber softener, anti-rust of metal devices and raw material of rust proof grease.
Vaseline pharma grade is suitable for preparing ingredients of medicine ointment and skin protection cream.

Vaseline pharma grade can be used for the anticorrosion of mechanical equipments, metal and parts, especially precision instruments, medical equipment and other advanced products.
Vaseline pharma grade can be used as lubricating grease in anti-attrition parts of machines when the temperature is not high and the mechanical load is not large.
Vaseline pharma grade can be used as the ingredients of high-end cosmetics and other daily necessities, such as skin care cream, hair cream, lipstick pomade ,etc.

Vaseline pharma grade softens and smoothes the skin. It forms a film on the skin’s surface, preventing moisture loss caused by evaporation, and protecting against irritation.
Vaseline pharma grade disadvantage lies in the difficulty of effectively and properly removing it from the skin.
Studies indicate that Vaseline pharma grade accelerates the recovery of skin surface lipids, permeating throughout the stratum corneum layer, and allowing normal barrier recovery despite its occlusive properties.

Vaseline pharma grade does not form or act as an impermeable membrane.
Vaseline pharma grade is a purified mixture of semisolid hydrocarbons from petroleum.
Vaseline pharma grade imparts a greasier feeling than other emollients and also has the potential for clogging pores and causing comedogenicity.

Vaseline pharma grade can cause allergic skin rashes, petrolatum is non-toxic to the skin when properly purified and of high grade.
Vaseline pharma grade is a release agent, lubricant, and defoaming agent that is a purified mixture of semisolid hydrocarbons obtained from petro- leum.
Vaseline pharma grade varies in color from white to yellow.

Vaseline pharma grade is used in bakery products, dehydrated fruits and vegetables, and egg white solids.
Vaseline pharma grade is used all over the world to protect and heal dry skin, from dry, cracked hands to hard skin on heels, as well as for beauty purposes, like softening the lips or highlighting the cheekbones.
Vaseline pharma grade is used to protect and repair the skin.

Vaseline pharma grade is used for preventing diaper rash, but it can also be used to protect minor cuts and burns, to soften skin, and to lock in moisture in dry, cracked skin.
Vaseline pharma grade is used as an ointment base, protective dressing and soothing applications to skin.
Vaseline pharma grade is offer excellent barrier to moisture and thus prevents moisture loss from skin.

Vaseline pharma grade is used in formulating various cosmetic and personal care preparations.
Vaseline pharma grade care and protection covering because Vaseline serves as an excellent and inexpensive water repellent, it can be used to coat corrosion-prone items such as metallic trinkets, non-stainless steel knives and gun barrels prior to storage.
Vaseline pharma grade usually definitely every three months (after regular cleaning) the wheels be coated with it.

Vaseline pharma grade’s used to soften and protect smooth leather goods such as bicycle saddles, book, motorcycle clothing, and is used to shine patent leather shoes (when applied in a thin coat and then lightly polished).
Vaseline pharma grade is used as part of a mixture of hydrocarbons, including those with greater (paraffin wax)and less (mineral oil) molecular weights, to moisten modeling clay that is not drying like plasticine.
In transmission lines, split tees that are installed for HOT TAP operations or valves whose polyurethane insulation is damaged or cannot be buried, one of the best options is to use petroleum with a 4-layer system with Rock shield tape be.

In faucets or equipment that need periodic repairs and services.
The most effective and least expensive method is to use petroleum coating. Using this coating while preventing corrosion for a long period of time will not limit periodic inspections and repairs because this coating has never hardened and can be easily opened and closed again.
Vaseline pharma grade Can be used to coat the inner walls of terrariums to prevent animals from crawling out and escaping.

Vaseline pharma grade is widely used in various industries and applications, including personal care, pharmaceuticals, and lubricants.
In personal care products, Vaseline pharma grade is often used as a moisturizer to protect and soothe dry or chapped skin, as well as to create a barrier between the skin and external irritants.
Vaseline pharma grade can also be used as a base for various cosmetic formulations.

In the pharmaceutical industry, Vaseline pharma grade is used as a base for ointments and other topical medications.
Vaseline pharma grade can help to enhance the penetration of active ingredients into the skin and provide a protective barrier against moisture and other external factors.
Vaseline pharma grade is also commonly used as a lubricant for machinery and other mechanical devices.

Vaseline pharma grade is high viscosity and water-resistant properties make it an effective lubricant for a variety of applications.
Vaseline pharma grade is a versatile and widely used substance with a variety of practical applications in different industries.
Most uses of Vaseline pharma grade exploit its lubricating and coating properties, including use on dry lips and dry skin.

Below are some examples of the uses of Vaseline pharma grade.
Vaseline pharma grade, or carbolated petroleum jelly containing phenol to give the jelly additional antibacterial effect, has been discontinued.
During World War II, a variety of Vaseline pharma grade called red veterinary petrolatum, or Red Vet Pet for short, was often included in life raft survival kits.

Acting as a sunscreen, Vaseline pharma grade provides protection against ultraviolet rays.
The American Academy of Dermatology recommends keeping skin injuries moist with Vaseline pharma grade to reduce scarring.
A verified medicinal use is to protect and prevent moisture loss of the skin of a patient in the initial post-operative period following laser skin resurfacing.

Vaseline pharma grade is used extensively by otolaryngologists—ear, nose, and throat surgeons—for nasal moisture and epistaxis treatment, and to combat nasal crusting.
Large studies have found Vaseline pharma grade applied to the nose for short durations to have no significant side effects.
Historically, Vaseline pharma grade was also consumed for internal use and even promoted as "Vaseline confection".

Vaseline pharma grade today is used as an ingredient in skin lotions and cosmetics, providing various types of skin care and protection by minimizing friction or reducing moisture loss, or by functioning as a grooming aid (e.g., pomade).
Vaseline pharma grade is also used for treating dry scalp and dandruff.
By reducing the loss of moisture via transepidermal water loss, Vaseline pharma grade can prevent chapped hands and lips, and soften nail cuticles.

Vaseline pharma grade can be used to keep swimmers warm in water when training, or during channel crossings or long ocean swims.
Vaseline pharma grade can prevent chilling of the face due to evaporation of skin moisture during cold weather outdoor sports.
In the first part of the twentieth century, Vaseline pharma grade, either pure or as an ingredient, was also popular as a hair pomade.

When used in a 50/50 mixture with pure beeswax, Vaseline pharma grade makes an effective moustache wax.
Vaseline pharma grade can be used to reduce the friction between skin and clothing during various sport activities, for example to prevent chafing of the seat region of cyclists, or the nipples of long distance runners wearing loose T-shirts, and is commonly used in the groin area of wrestlers and footballers.
Vaseline pharma grade is commonly used as a personal lubricant, because it does not dry out like water-based lubricants, and has a distinctive "feel", different from that of K-Y and related methylcellulose products. However, it is not recommended for use with condoms during sexual activity, as it increases the chance of rupture.

In addition, petroleum jelly is difficult for the body to break down naturally, and may cause vaginal health problems when used for intercourse.
Vaseline pharma grade can be used to coat corrosion-prone items such as metallic trinkets, non-stainless steel blades, and gun barrels prior to storage as it serves as an excellent and inexpensive water repellent.
Vaseline pharma grade is used as an environmentally friendly underwater antifouling coating for motor boats and sailing yachts.

Vaseline pharma grade was recommended in the Porsche owner's manual as a preservative for light alloy (alleny) anodized Fuchs wheels to protect them against corrosion from road salts and brake dust.
Vaseline pharma grade can be used to finish and protect wood, much like a mineral oil finish.
Vaseline pharma grade is used to condition and protect smooth leather products like bicycle saddles, boots, motorcycle clothing, and used to put a shine on patent leather shoes (when applied in a thin coat and then gently buffed off).

Vaseline pharma grade can be used to lubricate zippers and slide rules.
Vaseline pharma grade was also recommended by Porsche in maintenance training documentation for lubrication (after cleaning) of "Weatherstrips on Doors, Hood, Tailgate, Sun Roof".
Vaseline pharma grade is used in bullet lubricant compounds.

Vaseline pharma grade is a useful material when incorporated into candle wax formulas.
Vaseline pharma grade softens the overall blend, allows the candle to incorporate additional fragrance oil, and facilitates adhesion to the sidewall of the glass.
Vaseline pharma grade is used to moisten nondrying modelling clay such as plasticine, as part of a mix of hydrocarbons including those with greater (paraffin wax) and lesser (mineral oil) molecular weights.

Vaseline pharma grade is used as a tack reducer additive to printing inks to reduce paper lint "picking" from uncalendered paper stocks.
Vaseline pharma grade can be used as a release agent for plaster molds and castings.
Vaseline pharma grade is used in the leather industry as a waterproofing cream.

Vaseline pharma grade can be used to fill copper or fibre-optic cables using plastic insulation to prevent the ingress of water, see icky-pick.
Vaseline pharma grade can be used to coat the inner walls of terrariums to prevent animals crawling out and escaping.
Vaseline pharma grade can be used to prevent the spread of a liquid.

For example, Vaseline pharma grade can be applied close to the hairline when using a home hair dye kit to prevent the hair dye from irritating or staining the skin.
Vaseline pharma grade is also used to prevent diaper rash.
Vaseline pharma grade is sometimes used to protect the terminals on batteries.

In automobiles, a silicone-based battery grease provides better protection as it is less likely to melt.
Vaseline pharma grade is used to gently clean a variety of surfaces, ranging from makeup removal from faces to tar stain removal from leather.
Vaseline pharma grade uses as an ointment base, protective dressing and soothing applications to skin.

These gels offer excellent barrier to moisture and thus prevent moisture loss from skin.
Pharma Vaseline pharma grades are used in formulating various cosmetic and personal care preparations like hair conditioners, hand cleaners, lip balms, massage creams, moisturizing lotions, and sun care products and in various pharmaceutical applications such as skin protecting ointments, medicated ointments etc.
Vaseline pharma grade uses as an ointment base, protective dressing and soothing applications to skin.

These gels offer excellent barrier to moisture and thus prevent moisture loss from skin.
Vaseline pharma grades are used in formulating various cosmetic and personal care preparations like hair conditioners, hand cleaners, lip balms, massage creams, moisturizing lotions, and sun care products and in various pharmaceutical applications such as skin protecting ointments, medicated ointments etc.
Vaseline pharma grade is widely used as a skin protectant and moisturizer.

Vaseline pharma grade helps prevent dryness, chapping, and cracking of the skin, making it a popular choice for dry or sensitive skin.
Vaseline pharma grade is commonly used to soothe and moisturize chapped lips.
Many lip balms and chapsticks contain Vaseline pharma grade as a key ingredient.

Vaseline pharma grade creates a barrier on the skin that helps protect wounds and minor cuts from external elements, promoting a conducive environment for healing.
Vaseline pharma grade to create a protective barrier on a baby's skin to prevent and alleviate diaper rash.
Vaseline pharma grade can be used to remove stubborn makeup, including waterproof mascara.

Vaseline pharma grade is applied to the face, allowed to sit, and then wiped away with a tissue or cotton pad.
Dermatologists may recommend Vaseline pharma grade for individuals with eczema or dermatitis to provide relief from itching and to lock in moisture.
Vaseline pharma grade is sometimes recommended for tattoo aftercare.

Vaseline pharma grade helps keep the tattooed skin moisturized during the healing process.
Vaseline pharma grade can be applied to exposed skin in cold weather to provide a protective barrier against windburn and cold temperatures.
Vaseline pharma grade is commonly used to reduce friction between the skin and clothing or footwear, helping to prevent chafing and blisters.

Vaseline pharma grade is used to tame frizz, moisturize hair ends, or as a base for making homemade hair masks.
In certain medical settings, Vaseline pharma grade may be used in combination with dressings or gauze to protect wounds or burns.
A small amount of Vaseline applied inside the nostrils can help prevent nasal dryness, especially in dry or cold climates.

Vaseline pharma grade's protective properties make it suitable as a barrier cream for individuals working in industries where they come into contact with irritants or chemicals.
Vaseline pharma grade is used to moisturize the paws of dogs.
Vaseline pharma grade is a common ingredient in hairball remedies for domestic cats.

Vaseline pharma grade is produced in three grades: pharmaceutical, cosmetic and industrial grade, and is used in various industries.
Vaseline pharma grade is used in the cosmetics industry to produce a variety of eye creams, hand and face creams, and cosmetics (lipsticks and body lotions, etc.) to produce a variety of soaps.
Vaseline pharma grade is mainly used to produce various ointments for burns.

Also, Vaseline pharma grade of the pharmaceutical grade is used to treat dry skin, cracked hands and feet, cracked lips, and cracked heels.
Vaseline pharma grade would be added with Aloe Vera compounds, honey wax, and vitamins E and A along with aromatic essential oils for daily use.
Vaseline pharma grade is used as a lubricant in industry, produces grease, and also stainless the pieces of equipment and devices that are made of iron in the industry.

Safety Profile:
Vaseline pharma grade is mainly used in topical pharmaceutical formulations and is generally considered to be a nonirritant and nontoxic material.
Animal studies, in mice, have shown Vaseline pharma grade to be nontoxic and noncarcinogenic following administration of a single subcutaneous 100 mg dose.
Similarly, no adverse effects were observed in a 2-year feeding study with rats fed a diet containing 5% of petrolatum blends.

Although Vaseline pharma grade is generally nonirritant in humans following topical application, rare instances of allergic hypersensitivity reactions have been reported,as have cases of acne, in susceptible individuals following repeated use on facial skin.
However, given the widespread use of Vaseline pharma grade in topical products, there are few reports of irritant reactions.
The allergic components of Vaseline pharma grade appear to be polycyclic aromatic hydrocarbons present as impurities.

The quantities of these materials found in Vaseline pharma grade vary depending upon the source and degree of refining.
Hypersensitivity appears to occur less with white petrolatum and it is therefore the preferred material for use in cosmetics and pharmaceuticals.
Vaseline pharma grade has also been tentatively implicated in the formation of spherulosis of the upper respiratory tract following use of a Vaseline pharma grade-based ointment packing after surgery,and lipoid pneumonia following excessive use in the perinasal area.

Other adverse reactions to Vaseline pharma grade include granulomas (paraffinomas) following injection into soft tissue.
Also, when taken orally, petrolatum acts as a mild laxative and may inhibit the absorption of lipids and lipid-soluble nutrients.
Vaseline pharma grade jelly contains mineral oil aromatic hydrocarbons (MOAH).

Many MOAH, mainly polycyclic aromatic hydrocarbons (PAH), are considered carcinogenic.
The content of both MOAH and PAH in Vaseline pharma grade products varies.
The risks of PAH exposure through cosmetics have not been comprehensively studied, but food products with low levels (<3%) are not considered carcinogenic.

Storage:
Vaseline pharma grade is an inherently stable material owing to the unreactive nature of its hydrocarbon components; most stability problems occur because of the presence of small quantities of impurities.
On exposure to light, these impurities may be oxidized to discolor the Vaseline pharma grade and produce an undesirable odor.
The extent of the oxidation varies depending upon the source of the Vaseline pharma grade and the degree of refinement.

Oxidation may be inhibited by the inclusion of a suitable antioxidant such as butylated hydroxyanisole, butylated hydroxytoluene, or alpha tocopherol.
Vaseline pharma grade should not be heated for extended periods above the temperature necessary to achieve complete fluidity (approximately 70°C).
Vaseline pharma grade may be sterilized by dry heat.

Although Vaseline pharma grade may also be sterilized by gamma irradiation, this process affects the physical properties of the Vaseline pharma grade such as swelling, discoloration, odor, and rheological behavior.
Vaseline pharma grade should be stored in a well-closed container, protected from light, in a cool, dry place.
Vaseline
Petrolatum, melting range 45 - 60;Petrolatum Yollew vaseline;pennsolinesoftyellow;penrecowhite;perfecta;petrolatumusp;protopet,alba;protopet,white1s cas no: 8009-03-8
VECTOR 4111 A
VECTOR 4111 A VECTOR 4111 Technical Datasheet VECTOR 4111 is a linear, pure SIS copolymer. Used for tape adhesives. Offers good purity and consistency, and high performance properties. Improves shear strength, heat resistance and aging resistance and color stability under thermal stress. VECTOR 4111 can be combined with hydrocarbon resins. Product Type Styrene Block Copolymers, SBC (SBS, SEBS, SEPS, SIS) > Styrene Isoprene Rubbers (SIS) Chemical Composition Styrene Isoprene Styrene Copolymer Physical Form Pellets VECTOR 4111 is a linear, pure SIS copolymer. Used for tape adhesives. Offers good purity and consistency, and high performance properties. Improves shear strength, heat resistance and aging resistance and color stability under thermal stress. VECTOR 4111 can be combined with hydrocarbon resins. Product Description Linear SIS (1) triblock copolymer. Contains <1% diblock copolymer. Low styrene, low modulus. VECTOR 4111A and VECTOR 4111N styrenic block copolymers are linear triblock copolymers with narrow molecular weight distributions. They are the softest pure triblock copolymers offered and show outstanding melt processability and elasticity, making them well-suited for use in elastomer compounds and polymer modification applications. The pure triblock also makes them well-suited for use in high shear, pressure sensitive adhesive applications. General Material Status Commercial: Active Features Block Copolymer Excellent Processability High Elasticity Narrow Molecular Weight Distribution Soft Uses Adhesives Plastics Modification Forms Pellets Physical Nominal Value Unit Test Method Density / Specific Gravity ASTM D792 Apparent (Bulk) Density g/cm³ ASTM D1895 Melt Mass-Flow Rate (MFR) (200°C/5.0 kg) g/10 min ASTM D1238 Bound Styrene % Internal Method Ash Content wt% ASTM D5630 Solution Viscosity - in 25 wt% Toluene (77°F) mPa·s ASTM D2196 Elastomers Nominal Value Unit Test Method Tensile Stress 2 (300% Strain) psi ISO 37 Tensile Stress 2 (Break) psi ISO 37 Tensile Elongation 2 (Break) % ISO 37 Hardness Nominal Value Unit Test Method Durometer Hardness (Shore A, 1 sec) ASTM D2240 Additional Information Nominal Value Unit Test Method Diblock Content wt% Internal Method Features Features may also be described by the following terms: Block Copolymer, High Elasticity, Highly Elastic, Narrow Molecular Weight Distribution, Narrow MW Distribution, Excellent Processability. Uses Uses may also be described by the following terms: Plastics Modification, Plastic Modification. VECTOR 4211A Datasheet Styrene Isoprene Styrene Block Copolymer Product Description Linear SIS triblock copolymer. Contains <1% diblock copolymer. Medium styrene, medium modulus. VECTOR 4211A and VECTOR 4211N styrenic block copolymers are linear triblock copolymers with narrow molecular weight distributions. They have a higher styrene content and higher modulus than VECTOR 4111A SIS, making them well-suited for use in elastomer compounds, polymer modification applications and pressure sensitive adhesive applications requiring high cohesion. VECTOR 4211A SIS is offered as a dense pellet supplied from the United States. VECTOR 4211N SIS is offered as a porous pellet supplied from China. General Material Status Commercial: Active Availability North America Features Block Copolymer Narrow Molecular Weight Distribution Uses Adhesives Plastics Modification Forms Pellets Physical Nominal Value Unit Test Method Density / Specific Gravity ASTM D792 Apparent (Bulk) Density g/cm³ ASTM D1895 Melt Mass-Flow Rate (MFR) (200°C/5.0 kg) g/10 min ASTM D1238 Bound Styrene % Internal Method Ash Content wt% Solution Viscosity - in 25 wt% Toluene (77°F) mPa·s ASTM D2196 Elastomers Nominal Value Unit Test Method Tensile Stress 2 (300% Strain) psi ISO 37 Tensile Stress 2 (Break) psi ISO 37 Tensile Elongation 2 (Break) % ISO 37 Hardness Nominal Value Unit Test Method Durometer Hardness (Shore A, 1 sec, Compression Molded) ASTM D2240 Additional Information Nominal Value Unit Test Method Diblock Content wt% Internal Method Features Features may also be described by the following terms: Narrow Molecular Weight Distribution, Narrow MW Distribution, Block Copolymer. Uses Uses may also be described by the following terms: Plastics Modification, Plastic Modification.
VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE)
DESCRIPTION:
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is a mild, anionic surfactant.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is the sodium salt of fatty acids-coco-2-sulfo- ethyl esters.
SCI 85 is highly suitable for use in personal care products.

CAS Number, 61789-32-0 / 58969-27-0
EINECS/ELINCS No:, 263-052-5
Chem/IUPAC Name:, Fatty acids, coco, 2-sulfoethyl esters, sodium salts
COSING REF No:, 79383



SYNONYMS OF VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
Sodium Cocoyl Ethyl Ester Sulfonate, 2-Sulfoethyl Ester


Vegarol SCI 85 (Sodium Cocoyl Isethionate) is a naturally-derived ingredient that comes from the fatty acids that are present in isethionic acid and coconut oil.
These fatty acids are reacted with sodium isethionate and the mixture is heated to remove any water left behind.
Further, the mixture is distilled to remove excess fatty acids.
In its raw form, Sodium Cocoyl Isethionate appears as a fine white powder.


Vegarol SCI 85 (Sodium Cocoyl Isethionate) is a very mild surfactant with highest active content, making it a preferable choice for the formulator because the usage rate is lower, providing freedom to add extra ingredients to customize formulations.

Sodium Cocoyl Isethionate is a gentle surfactant derived from coconut.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) can be used in a variety of cosmetic recipes.
Sodium Cocoyl Isethioniate (SCI) acts as a foaming and cleansing ingredient.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) leaves your skin feeling soft and silky.
This is an ingredient used in products like soap, bath bombs, bubble bars, and shampoo. Recommended usage rate: 3%-20%

Sodium Cocoyl Isethionate Powder is a top anionic powder surfactant, very gentle and derived from all vegetable, renewable resources.
Plus, Vegarol SCI 85 (Sodium Cocoyl Isethionate) is Biodegradeable.
SCI powder / Sodium Cocoyl Isethionate is used in many applications.


USES OF VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):

Vegarol SCI 85 (Sodium Cocoyl Isethionate) is primarily a surfactant that is gentle on the surface and provides many benefits to skin and hair.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is thus commonly used in the cosmetic world.

Skin care:
Vegarol SCI 85 (Sodium Cocoyl Isethionate) differs from other surfactants in the way that it does not strip the skin of moisture, making it feel dehydrated.
Instead, Sodium Cocoyl Isethionate produces a rich foam that does not dry out or irritate the skin upon application

Hair care:
Vegarol SCI 85 (Sodium Cocoyl Isethionate) produces a rich creamy lather that makes the products easier to spread and feel good.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) also cleanses the shafts thoroughly because of its ability to mix well with both oil and water

Cosmetic products:
Vegarol SCI 85 (Sodium Cocoyl Isethionate) reduces the surface tension of the ingredients in a formulation - allowing them to mix well.
This prevents the separation of oil based and water based ingredients and results in an even consistency of the cosmetic products


Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Shampoos
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Shower gels
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Liquid Soap

Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Bubble baths
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Foaming Shaving Soaps
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Baby Products


Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Syndet bars
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in Eye makeup remover


Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in is recommended for systems where low levels of fatty acid are needed; for example, shampoos, bath and shower gels and liquid soaps.

Vegarol SCI 85 (Sodium Cocoyl Isethionate) is used in may need medium, even heat to disperse in certain surfactant systems.
The extra steps are really worth it for the excellent results.


This is a wonderful surfactant to work with and make products from.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is derived from natural coconut oil.
Naturally derived and biodegradable.

Vegarol SCI 85 (Sodium Cocoyl Isethionate) is mild to the skin and eyes.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is an excellent foamer in hard or soft water.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) Imparts a soft after feel to the skin.





ORIGIN OF VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
Sodium Cocoyl Isethionate is a naturally-derived ingredient that comes from the fatty acids that are present in isethionic acid and coconut oil.
These fatty acids are reacted with sodium isethionate and the mixture is heated to remove any water left behind.
Further, the mixture is distilled to remove excess fatty acids.


BENEFITS AND USES OF VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is one of the best sulfate-free alternatives available in the market.
Owing to its mild cleansing and high foaming capabilities, it is traditionally used to make solid shampoo bars, conditioner bars, syndet bars, and bath bombs.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is outstanding for use in products for color-treated hair.

Its peculiarity lies in the fact that it resists hard water and therefore prevents the formation of scum, which ensures no residue is left behind.
Vegarol SCI 85 (Sodium Cocoyl Isethionate) lathers pretty well when used as a stand-alone surfactant base and hence appeals to the sense of cleaning.

Vegarol SCI 85 (Sodium Cocoyl Isethionate) offers beautiful, gentle “lace glove” lather to our products.
It’s also naturally acidic, so Vegarol SCI 85 (Sodium Cocoyl Isethionate) helps our end products have a skin-friendly pH with less (or no) adjusting.


Vegarol SCI 85 (Sodium Cocoyl Isethionate) has Very low irritation
Anywhere mildness and rich dense foam is needed
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is Excellent foamer
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is Rich and abundant stable lather


Vegarol SCI 85 (Sodium Cocoyl Isethionate) is Lubricity
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is Biodegradable
Vegarol SCI 85 (Sodium Cocoyl Isethionate) Imparts silky skin after-feel


Vegarol SCI 85 (Sodium Cocoyl Isethionate) has Creaminess/rich feel
Vegarol SCI 85 (Sodium Cocoyl Isethionate) has Hard water tolerant
Vegarol SCI 85 (Sodium Cocoyl Isethionate) Leaves no soap scum

Vegarol SCI 85 (Sodium Cocoyl Isethionate) has Limited water solubility
Vegarol SCI 85 (Sodium Cocoyl Isethionate) Rinses without residue
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is Easy to use powder form



HOW VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE) WORKS?:
Vegarol SCI 85 (Sodium Cocoyl Isethionate) is a surfactant that has a hydrophobic alkyl tail and a hydrophilic sulfonate anion.
These help to remove dirt and grime from the surface by attaching themselves to oil/grease and water respectively.


CONCENTRATION AND SOLUBILITY OF VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
The maximum suggested concentration for use in various formulations is upto 40% in rinse-off applications and 17% in leave on applications.
To increase its solubility in liquid detergents, betaine, nonionic sugar surfactants, glyceramides, polyglycosides, etc can be used.

HOW TO USE VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
Mix in the surfactant phase of your choice.
Heat slowly on low heat.
Stir using a high-shear stick blender to prevent excess foaming.
Add surfactant mix to the rest of the formulation.






CHEMICAL AND PHYSICAL PROPERTIES OF VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
Melting Point, 191-194°C
pH, 6.0-8.0
Solubility, Soluble in water
Solubility, 1 M HCl
Color, White to Pale-brown
Boiling point, 314.29°C
Pka, 2.2 (at 25℃)
BRN, 392441
Alpha, -11.65 º (c=5,DIL HCL/H2O 50/50)
Storage temp., Store below +30°C.
Refractive index, -12 ° (C=5, 1mol/L HCl)
Form, Powder
EPA Substance Registry System, L-Tyrosine (60-18-4)
PH, 6.5 (0.1g/l, H2O)
FEMA, 3736 | L-TYROSINE
InChIKey, OUYCCCASQSFEME-QMMMGPOBSA-N
Fp, 176 °C
Density, 1.34
JECFA Number, 1434
Water Solubility, 0.45 g/L (25 ºC)
Melting point, >300 °C (dec.) (lit.)
Merck, 14,9839
Stability, Stable. Incompatible with strong oxidizing agents, strong reducing agents.
Optical activity, [α]20/D 11.5±1.0°, c = 4% in 1 M HCl
NIST Chemistry Reference, Tyrosine (60-18-4)
CAS DataBase Reference, 60-18-4 (CAS DataBase Reference)
INCI: Sodium Cocoyl Isethionate
Assay: 85%
Appearance: White powder
Use rate: 1.0 – 20.0%
Solubility: Water and liquid surfactants
pH (5% in water): 5.0 –7.0
Charge: Anionic
Melting Point: 179 – 180°C
INCI NameSodium Cocoyl Isethionate
Chemical NameFatty acids coco 2-sulfoethyl esters sodium salts
HS Code3402.3990
CAS Number61789-32-0
Product FormGranules
Region of OriginAsia Pacific
Reach01-2119974104-40-XXXX
Product GroupIsethionates




SAFETY INFORMATION ABOUT VEGAROL SCI 85 (SODIUM COCOYL ISETHIONATE):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

VELSAN CCT
CAS NUMBER: 73398-61-5

INCI-Name: Caprylic/ CapricTriglyceride

Velsan CCT acts as a liquid emollient.
Velsan CCT offers characteristics such as low tackiness and good spreadability.
Velsan CCT is used in skin care formulations.
Velsan CCT acts as emollient, lubricant and solvent.
Velsan CCT is used in antiperspirants & deodorants - roll on and stick, shaving, baby care, body care, facial care, sun care, facial make-up, lip products, sprayable emulsions, cleansers, toners, eye care, specific skin care treatments, feets, hands as well as nails, shampoos and hair coloring.

Propeties of Velsan CCT:
-Low color, low odor, constant quality, medium chain triglyceride oil.

Applications & Uses of Velsan CCT:
Markets:
-Personal Care

Applications of Velsan CCT:
-Personal Care — Beauty & Care
-Baby Care
-Bath & Shower
-Color Cosmetics
-Hair Care
-Skin Care
-Sun Care

Application Format of Velsan CCT:
-Creams
-Gel
-Leave On
-Lotions
-Powder
-Rinse Off
-Spray
-Stick
-Wipes

Baby Care Applications of Velsan CCT:
-Baby Lotion
-Baby Oil
-Baby Shampoo
-Baby Sunscreen
-Baby Wipes
-Cradle Cap Treatment

Bath & Shower Applications of Velsan CCT:
-Baby Bubble Bath
-Bath Oils, Tablets & Salts
-Body Wash & Cleanser

Color Cosmetic Applications of Velsan CCT:
-BB Creams
-Blush
-CC Cream
-Concealer
-Eyebrow Enhancers
-Face Powder
-Foundation

Hair Care Applications of Velsan CCT:
-Anti-Dandruff Products
-Anti-Hair Loss Products
-Beard Oil

Nail Care Applications of Velsan CCT:
-Cuticle Oils, Creams & Lotions

Skin Care Applications of Velsan CCT:
-After Shaves
-Anti-Aging Products
-Around Eye Creams & Gels
-Body Firming Lotion
-Body Oil
-Facial Cleanser
-Facial Moisturizer
-Foot Moisturizer

Sun Care Applications of Velsan CCT:
-After Sun Products
-Baby Sunscreen

Treatment Product Applications of Velsan CCT:
-Acne Treatments
-Anti-Dandruff Products
-Cradle Cap Treatment
-Eczema Treatment

GRADES: Cosmetic
SOURCE/ORIGIN: Plant and synthetic
VEGAN SUITABLE: Suitable
PALM DERIVATIVES STATUS: Palm derived (RSPO; sustainable)

Chemical Family: Glycerides

Ingredient Origin:
-Oleochemical
-Synthetic
-Cosmetic Ingredients Functions:
-Emollient
-Occlusive

Technologies: Cosmetic Ingredients

Product Families:
-Cosmetic Ingredients — Functionals
-Conditioners & Emollients
-Other Functional Additives

Velsan CCT benefits Claims:
-Emolliency
-Non-Tacky
-Spreadability

Function: Occlusive, Re-Fatting Agent, Emollient
Ingredient Origin: Synthetic, Oleochemical

Velsan CCT applications/Recommended for:
Decorative cosmetics/Make-up>Eye pencils
Decorative cosmetics/Make-up>Eyes Shadows & Creams
Decorative cosmetics/Make-up>Lipsticks & Glosses
Decorative cosmetics/Make-up>Mascaras Decorative cosmetics/Make-up>Nail treatments
Hair care (Shampoos, Conditioners & Styling)>Bleaches, dyes & colors products
Hair care (Shampoos, Conditioners & Styling)>Shampoos
Skin care (Facial care, Facial cleansing, Body care, Baby care)>Baby care
Skin care (Facial care, Facial cleansing, Body care, Baby care)>Body care
Skin care (Facial care, Facial cleansing, Body care, Baby care)>Facial care>Eye Care Gels & creams
Skin care (Facial care, Facial cleansing, Body care, Baby care)>Facial cleansing>Cleansing lotions & toners
Sun care (Sun protection, After-sun & Self-tanning)
Toiletries (Shower & Bath, Oral care...)>Antiperspirants & deodorants>Deodorants sticks and roll-on
Toiletries (Shower & Bath, Oral care...)>Foot care
Toiletries (Shower & Bath, Oral care...)>Shaving Decorative cosmetics/Make-up>Eye liners
VEOVA 10
2-Butoxyethyl acetate; 1-Acetoxy-2-butoxyethane; BCA; Ethylene glycol monobutyl ether acetate cas no: 112-07-2
VERDYL ACETATE
Verdyl acetate is a natural product found in Solanum lycopersicum with data available.
Verdyl Acetate is cycloverdyl acetate jasmacyclene .


CAS Number: 5413-60-5
EC Number: 219-700-4
MDL Number: MFCD00135806
Molecular Formula: C12H16O2



SYNONYMS:
Verdyl acetate, 4,7-Methanoinden-6-ol, 3a,4,5,6,7,7a-hexahydro-, acetate, Dihydro-nordicyclopentadienyl acetate, Tricyclodecen-4-yl 8-acetate, 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate, 4,7-Methano-1H-inden-5-ol, 3a,4,5,6,7,7a-hexahydro-, 5-acetate, 3a,4,5,6,7,7a-Hexahydro-4,7-methano-1H-inden-5-yl acetate, 4,7-Methanoinden-5-ol, 3a,4,5,6,7,7a-hexahydro-, acetate, Tricyclo(5.2.1.02,6)dec-3-en-9-yl acetate, Tricyclodecenyl acetate, Tricyclo(5.2.1.02,6)dec-4-en-8-yl acetate, tricyclodecenyl acetate, dihydrodicyclopentadiene acetate, Hexahydro-4,7-methanoinden-5(6)-yl acetate, 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate, 4,7-Methano-1H-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-, 6-acetate, 4,7-Methano-1H-inden-6-ol,3a,4,5,6,7,7a-hexahydro-,6-acetate, 4,7-Methanoinden-6-ol,3a,4,5,6,7,7a-hexahydro-,acetate, 4,7-Methano-1H-inden-6-ol,3a,4,5,6,7,7a-hexahydro-,acetate, Verdyl acetate, 4,7-Methano-3a,4,5,6,7,7a-hexahydroinden-6-yl acetate, Herbaflorat, NSC 6598, Greenyl acetate, 8-Acetoxytricyclo[5.2.1.02,6]dec-3-ene, Jasmacyclene, 3a,4,5,6,7,7a-Hexahydro-1H-4,7-methanoinden-6-yl acetate, Verdyl acetate, 5413-60-5, Jasmacyclen, 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-yl acetate, Tricyclodecenyl acetate, Tricyclodecen-4-yl 8-acetate, 4,7-Methano-1H-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-, acetate, Greenyl acetate, Dihydro-nordicyclopentadienyl acetate, 3a,4,5,6,7,7a-Hexahydro-4,7-methanoinden-6-yl acetate, 5232EN3X2F, NSC-6598, MFCD00135806, 4,7-Methanoinden-6-ol, 3a,4,5,6,7,7a-hexahydro-, acetate, 4,7-Methano-1H-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-, 6-acetate, Herbaflorat, NSC 6598; Herbaflorat; Greenyl acetate, NSC 6598, EINECS 226-501-6, JASMACYCLENE, BRN 1949487, AI3-20146, SCHEMBL114981, UNII-5232EN3X2F, DTXSID4029270, NSC6598, Dihydro-nor-dicyclopentadienyl acetate, AKOS027276455, BS-42422, SY316742, J217.985G, NS00003520, 8-acetoxytricyclo[5,2,1,0 2,6]dec-3-ene, 8-tricyclo[5.2.1.02,6]dec-3-enyl acetate, E76501, EC 226-501-6, 8-ACETOXYTRICYCLO(5.2.1.02,6)DEC-3-ENE, W-105670, Q10878625, 3a,4,5,6,7,7a-hexahydro-1H-4,7-methanoinden-6-ylacetate, ACETIC ACID TRICYCLE(5.2.1.0(SUP 2,6))DECA-3-ENE-8-YL ESTER, 3A,4,5,6,7,7A-HEXAHYDRO-1H-4,7-METHANOINDEN-6-YL ACETATE, 4,7-METHANO-1H-INDEN-6-OL, 3A,4,5,6,7,7A-HEXAHYDRO-, 6-ACETATE, 4,7-METHANO-1H-INDEN-6-OL, 3A,4,5,6,7,7A-HEXAHYDRO-, ACETATE, 8-ACETOXYTRICYCLO(5.2.1.02,6)DEC-3-ENE, ACETIC ACID TRICYCLE(5.2.1.0(SUP 2,6))DECA-3-ENE-8-YL ESTER, GREENYL ACETATE, J217.985G, JASMACYCLENE, NSC-6598, VERDYL ACETATE, DIHYDRO-DICYCLOPENTADIENYL ACETATE, 4,7-Methano-1H-Inden-6-ol, 3a,4,5,6,7,7a-Hexahydro-, Acetate, Dihydro-Nordicyclopentadienyl Acetate, Tricyclodecen-4-yl 8-Acetate, Tricyclodecenyl Acetate (IFRA)



Verdyl Acetate, also known as bornyl acetate, is a naturally occurring organic compound with a pleasant, woody aroma.
Verdyl Acetate is found in various essential oils, most notably in the oils of coniferous trees like pine, fir, and cedar, as well as in some herbs like rosemary and sage.


This ester is prized for Verdyl Acetate's aromatic properties and is a common ingredient in perfumery and fragrance industries.
Verdyl acetate's fragrance profile is characterized by its fresh, earthy, and slightly floral notes, making it a popular choice for adding depth and complexity to perfumes, colognes, and scented products.


Beyond its olfactory appeal, verdyl acetate also boasts potential therapeutic benefits, including its purported ability to promote relaxation and reduce stress when used in aromatherapy.
This versatile compound, Verdyl Acetate, continues to be an essential component in the world of fragrance and aromatics, captivating our senses with its delightful scent.


Verdyl Acetate, also known as cycloverdyl acetate jasmacyclene, is a light-floral green soapy compound .
Verdyl Acetate is a clear to straw yellow liquid and is not present in nature .
All products of Verdyl Acetate are synthetic .


Verdyl acetate is a natural product found in Solanum lycopersicum with data available.
Verdyl Acetate is cycloverdyl acetate jasmacyclene .
Verdyl Acetate is light-floral green soapy.


Verdyl Acetate is the ester that conforms to the formula: C12H16O2.
Verdyl Acetate is a synthetic aromatic chemical.
Verdyl Acetate has a shelf life of 24 months.



USES and APPLICATIONS of VERDYL ACETATE:
Application & Usage: Verdyl Acetate is used Fine Fragrances, Beauty care, Hair care , Laundry Care.
Verdyl Acetate has a strong and lasting delicate fragrance and is used in flavor essences such as modulation lavandula angustifolia, the banksia rose, fragrance are strange, chypre, and for makeup .


Application & Usage: Verdyl Acetate is used Fine Fragrances, Beauty care, Hair care , Laundry Care
Verdyl Acetate is an excellent modifier & provides floral accords an attractive green fruity volume with a sweet anise and wood background.
Verdyl Acetate is used for perfuming soaps, detergents and air freshners.


Verdyl Acetate is used fine Fragrances, Beauty care, Hair care, Laundry Care.
Perfumery uses of Verdyl Acetate: Verdyl acetate, with its woody and floral notes, is an essential component in high-end perfumes, providing a lasting and captivating fragrance.


Aromatherapy uses of Verdyl Acetate: In aromatherapy, verdyl acetate is utilized to create calming essential oil blends that promote relaxation and reduce stress.
Flavorings: Verdyl Acetate adds a subtle piney flavor to certain food and beverage products, enhancing their taste profiles.


Cosmetics: Verdyl acetate is used in cosmetics such as lotions and creams to imbue them with a pleasant, nature-inspired scent, enhancing the user's sensory experience.
Cleaning Products: Its fresh and clean aroma makes verdyl acetate a popular choice for adding fragrance to various household cleaning items, leaving spaces smelling rejuvenated.


Pharmaceuticals: In some pharmaceutical preparations, verdyl acetate is incorporated for both its fragrance and its potential calming effects, contributing to a more pleasant medication experience.



MOLECULAR STRUCTURE ANALYSIS OF VERDYL ACETATE:
The molecular formula of Verdyl Acetate is C12H16O2 .
The IUPAC name of Verdyl Acetate is 8-tricyclo [5.2.1.0 2,6 ]dec-3-enyl acetate .
The molecular weight of Verdyl Acetate is 192.25 g/mol .



PHYSICAL AND CHEMICAL PROPERTIES ANALYSIS OF VERDYL ACETATE:
Verdyl Acetate is a clear to straw yellow liquid .
Verdyl Acetate is insoluble in water but soluble in alcohol.
Verdyl Acetate is stable under normal conditions .



SYNTHESIS ANALYSIS OF VERDYL ACETATE:
The synthetic method of Verdyl Acetate involves a long production reaction scheme, which is considered dangerous and not suitable for industrial production due to its low synthetic yield .
A detailed synthetic method can be found in a patent .



PHYSICAL and CHEMICAL PROPERTIES of VERDYL ACETATE:
Molecular Weight: 192.25 g/mol
XLogP3-AA: 2.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 192.115029749 g/mol
Monoisotopic Mass: 192.115029749 g/mol
Topological Polar Surface Area: 26.3 Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 295
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 5
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Beilstein Number: 1949487
MDL: MFCD00135806
XlogP3-AA: 2.20 (est)
Molecular Weight: 192.25792000
Formula: C12 H16 O2
AL number: 3046
CAS number: To be assigned
CAS number (unlabelled): 5413-60-5
Molecular Formula: C12H16O2
Molecular Weight: 194.24
Assay: 95% min.
Appearance: colorless to pale yellow clear liquid (est)
Assay: 96.00 to 100.00 sum of isomers

Food Chemicals Codex Listed: No
Specific Gravity: 1.07000 to 1.08000 @ 25.00 °C
Refractive Index: 1.49300 to 1.49700 @ 20.00 °C
Boiling Point: 258.42 °C @ 760.00 mm Hg (est)
Acid Value: 1.00 max. KOH/g
Vapor Pressure: 0.014000 mmHg @ 25.00 °C (est)
Flash Point: > 212.00 °F TCC (> 100.00 °C)
logP (o/w): 3.119 (est)
Shelf Life: 24.00 month(s) or longer if stored properly
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light
Soluble in: alcohol kerosene,
paraffin oil, water, 177.4 mg/L @ 25 °C (est),

Stability: acid cleaner, alcoholic lotion,
antiperspirant, bleach, deo stick,
detergent perborate, fabric softener,
foam bath, hard surface cleaner,
liquid detergent, shampoo, soap,
SpectraBase Compound ID: ITZsnzG8ZOP
InChI: InChI=1S/C12H16O2/c1-7(13)14-12-6-8-5-11(12)10-4-2-3-9(8)10/h2-3,8-12H,4-6H2,1H3
InChIKey: RGVQNSFGUOIKFF-UHFFFAOYSA-N
Molecular Weight: 192.26 g/mol
Molecular Formula: C12H16O2
Exact Mass: 192.11503 g/mol
Appearance at 20°C: Clear mobile liquid
Color: Colorless to pale yellow

Odor: Fruit, green, wood, anise, floral, ozone
Optical Rotation (°): -0.5 / 0.5
Density at 20°C (g/mL): 1.068 - 1.078
Refractive Index ND20: 1.4930 - 1.4970
Flashpoint (°C): 116
Solubility: Soluble in ethanol 96º
Assay (% GC): Sum of isomers > 98
Acid Value (mg KOH/g): < 1
CAS Number: 5413-60-5
Market Applications: Flavor & Fragrance
IUPAC Name: 3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-yl acetate
CFR Number: N/A
EU Number: 226-501-6
HS Code: 2915.39.9050

Aroma Profile: Floral
CAS Registry Number: 5413-60-5
Unique Ingredient Identifier: 5232EN3X2F
Molecular formula: C12H16O2
International Chemical Identifier (InChI): RGVQNSFGUOIKFF-UHFFFAOYSA-N
SMILES: C1(CC2CC1C3C2C=CC3)OC(=O)C
FEMA Number: N/A
EINECS: 219-700-4
Formula: C12 H16 O2
Molecular Weight: 192.00 g/mol
Product Name: Verdyl acetate
CAS No.: 5413-60-5
EINECS No.: 226-501-6
Molecular Formula: C12H16O2

Molecular Weight: 192.25
Appearance: A colorless viscous liquid.
Boiling point: 288.25°C (rough estimate)
Density: 1.0240 (rough estimate)
Storage temp: Sealed in dry, Room Temperature
Water Solubility: 10μg/L at 30℃
Chemical Name: 3A,4,5,6,7,7A-HEXAHYDRO-4,7-METHANOINDEN-6-YL ACETATE
Chemical Formula: C12 H16 O2
Family: Floral
CAS N°: 5413-60-5
EINECS N°: 226-501-6
FEMA N°: -
PHYSICO-CHEMICAL PROPERTIES

Flash Point: > 100°C
Refractive Index ND20: [1.492 - 1.498]
Specific Gravity (D20/20): [1.072 - 1.082]
Purity: > 98% (SUM OF ISOMERS)
Molecular Weight: 192
Chemical Formula: C12H16O2
CAS Number: 5413-60-5
Color: Clear Colorless Liquid
Shelf Life: 12 months
Form: Liquid
IUPAC Name: 8-tricyclo[5.2.1.02,6]dec-3-enyl acetate
InChI: InChI=1S/C12H16O2/c1-7(13)14-12-6-8-5-11(12)10-4-2-3-9(8)10/h2-3,8-12H,4-6H2,1H3
InChI Key: RGVQNSFGUOIKFF-UHFFFAOYSA-N
Canonical SMILES: CC(=O)OC1CC2CC1C3C2C=CC3

Molecular Formula: C12H16O2
DSSTOX Substance ID: DTXSID4029270
Molecular Weight: 192.25 g/mol
Physical Description: Liquid; Liquid, Other Solid
Product Name: Verdyl acetate
CAS RN: 5413-60-5
Product Name: 4,7-Methano-3a,4,5,6,7,7a-hexahydroinden-6-yl acetate
CAS No.: 5413-60-5
Molecular Formula: C12H16O2
InChIKey: RGVQNSFGUOIKFF-UHFFFAOYSA-N
Molecular Weight: 192.25 g/mol
Exact Mass: 192.25
EC Number: 226-501-6
UNII: 5232EN3X2F
NSC Number: 6598
DSSTox ID: DTXSID4029270

HScode: 2915390090
Categories: Synthetic Fragrances
PSA: 26.3
XLogP3: 2.2
Appearance: Clear colorless liquid
Density: 1.12 g/cm3
Boiling Point: >200°C
Flash Point: >100°C CC
Refractive Index: 1.536
Organoleptic Note: Green and woody, with a sweet anisic note
Assay: 98% min
Specific Gravity: 1.070 - 1.080
Insolubility: In water
Color: Clear, colorless liquid
Solubility: Soluble in alcohol, kerosene, and paraffin oil



FIRST AID MEASURES of VERDYL ACETATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of VERDYL ACETATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry. Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of VERDYL ACETATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of VERDYL ACETATE:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of VERDYL ACETATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of VERDYL ACETATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available

VERDYL ACETATE
Verdyl acetate, also known as bornyl acetate, is a naturally occurring organic compound with a pleasant, woody aroma.
Verdyl acetate is found in various essential oils, most notably in the oils of coniferous trees like pine, fir, and cedar, as well as in some herbs like rosemary and sage.
Verdyl acetate is prized for its aromatic properties and is a common ingredient in perfumery and fragrance industries.

CAS: 5413-60-5
MF: C12H16O2
MW: 192.25
EINECS: 226-501-6

Synonyms
TRICYCLODECENYL ACETATE;VERDYL ACETATE;3a,4,5,6,7,7a-hexahydro-4,7-methanoinden-6-ylacetate;4,7-Methano-1H-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-, acetate;4,7-Methano-1H-inden-6-ol,3a,4,5,6,7,7a-hexahydro-,acetate;4,7-Methanoinden-6-ol, 3a,4,5,6,7,7a-hexahydro-, acetate;3A,4,5,6,7,7A-HEXAHYDRO-4,7-METHANO-1(3)H-INDEN-6-YL ACETATE;CYCLACET

Verdyl acetate's fragrance profile is characterized by its fresh, earthy, and slightly floral notes, making it a popular choice for adding depth and complexity to perfumes, colognes, and scented products.
Beyond its olfactory appeal, verdyl acetate also boasts potential therapeutic benefits, including its purported ability to promote relaxation and reduce stress when used in aromatherapy.
Verdyl acetate continues to be an essential component in the world of fragrance and aromatics, captivating our senses with its delightful scent.
Verdyl acetate, with its woody and floral notes, is an essential component in high-end perfumes, providing a lasting and captivating fragrance.
By hydration and acetylization of dicyclopentadiene.

Verdyl acetate Chemical Properties
Boiling point: 288.25°C (rough estimate)
Density: 1.0240 (rough estimate)
Vapor pressure: 2.84Pa at 25℃
Refractive index: 1.5100 (estimate)
Storage temp.: Sealed in dry,Room Temperature
Solubility: 571.429g/L in organic solvents at 20 ℃
pka: 0[at 20 ℃]
Color: A colourless viscous liquid.
Odor: at 100.00 %. floral green soapy cedar pine woody
Odor Type: floral
Water Solubility: 10μg/L at 30℃
LogP: 0.924 at 35℃
CAS DataBase Reference: 5413-60-5
EPA Substance Registry System: Verdyl acetate (5413-60-5)
VINKOCIDE BIT 20 D
Vinkocide BIT 20 D is an aqueous dispersion with 20% 1,2-benzisothiazolin-3-one with a low pH.
Vinkocide BIT 20 D acts as a broad spectrum preservative.
Offers excellent chemical stability and excellent long-term efficacy.

CAS: 2634-33-5
MF: C7H5NOS
MW: 151.19
EINECS: 220-120-9

Synonyms
Benzisothiazolin-3-on (BIT);Benzo[d]isothiazol-3(2H)-one;1,2-Benzisothiazolin-3-One(MIT);2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(7),8,10-trien-5-one;1,2-benzo-isothiazolin-3-ketone;Acticide BIT;Apizas AP-DS;Bestcide 200K;1,2-Benzisothiazol-3(2H)-one;2634-33-5;1,2-Benzisothiazolin-3-one;1,2-benzothiazol-3-one;benzisothiazolone;Benzo[d]isothiazol-3(2H)-one;Benzo[d]isothiazol-3-one;1,2-Benzisothiazoline-3-one;Proxel;benzoisothiazol-3-one;Proxel PL;Benzo[d]isothiazol-3-ol;1,2-BENZISOTHIAZOL-3-ONE;2,3-dihydro-1,2-benzothiazol-3-one;Benzisothiazolin-3-one;1,2-benzoisothiazolin-3-one;Nipacide BIT;Proxel AB;3-Hydroxy-1,2-benzisothiazole;C7H5NOS;Proxel XL 2;1,2-Benzisothiazolone;1,2-benzisothiazolinone;1,2-Benzoisothiazol-3-one;IPX;CHEBI:167099;HRA0F1A4R3;1,2-Benzoisothiazoline-3-one;DTXSID5032523;Benzoisothiazol-3-one-13C6;1329616-16-1;2,3-dihydro-3-oxo-1,2-benzisothiazole;MLS-0254244.0001;Benzo(d)isothiazol-3(2H)-one;Caswell No. 079A;Caswell No. 513A
;Benzocil;Acticide BIT;Canguard BIT;Denicide BIT;Proxel BD;Proxel CF;Proxel TN;Proxel XL;Proxel BDN;Proxel GXL;Proxel Ultra 5;San-aibac AP;Proxel LV-S;Proxel Press Paste;Apizas AP-DS;Acticide BW 20;Bestcide 200K;Nipacide BIT 20;Parmetol B 7;Parmetol D 11;Proxel GXL(S);Proxel HL 2;Nuosept 485;Nuosept 491;Nuosept 495;Topcide 600;XBINX;CCRIS 6369;Denicide BIT 20N;Koralone B 119;Nipacide BIT 10W;Preventol BIT 20D;Proxel BD 20;Proxel Press Paste D;Bioban BIT 20DPG
;benzisothiazoline-3-one;Canguard BIT 20DPG;EINECS 220-120-9;SD 202 (bactericide);UNII-HRA0F1A4R3;Canguard Ultra BIT 20LE;EPA Pesticide Chemical Code 098901;BIT 10W;BIT 20;2-Thiobenzimide;2,3-Dihydrobenzisothiazol-3-one;SD 202;40991-37-5;ORISTAR BIT;1,2-BENZISOTHAZOL-3(2H)-ONE;1,2-Benzothiazolinone;Benzisothiazolone (BIT);Epitope ID:115004;Benzisothiazol-3(2H)-one;Benzo(D) Isothiazol-3-one;SCHEMBL26078;cid_17520;MLS00077103;REGID_for_CID_17520;CHEMBL297304;SCHEMBL5586024;DTXCID3012523;BDBM46658;HSDB 8271;BENZISOTHIAZOLINONE [INCI];HMS1755P21;HMS2706H20;Tox21_300489;MFCD00044001;1, 2-BENZISOTHIAZOLIN-3-ONE;AKOS001062434;AKOS030227972;AC-2653

Ideal for use in aqueous and water miscible systems.
Suitable for use in adhesives and glues.
Recommended dosage of Vinkocide BIT 20 D is 0.05-0.2%.
Vinkocide BIT 20 D is an aqueous dispersion with 20 % 1,2-Benzisothiazolin-3-onewith a low pH.
In many cases Vinkocide BIT 20 D can be used as the only preservative.
Depending on the conditions and applications Vinkocide BIT 20 D can be useful to combine it with other biocides to enhance the fungicidal efficacy.
Vinkocide BIT 20 D is highly suitable for the preservation of a wide variety of aqueous products due to their good properties like good stability at high pH (3-13) as well as good stability at high temperatures.

Vinkocide BIT 20 D is an irritant and also a skin sensitizer.
Occupational allergie contact dermatitis has been reported mainly related to the use of cutting oils and greases in paint manufacturers, pottery mouldmakers, acrylic emulsion manufacturers, plumbers, printers and lithoprinters, paper makers, an analyticallaboratory, a rubber factory, and in employees manufacturing air fresheners.
Vinkocide BIT 20 D is an organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion.

Vinkocide BIT 20 D has a role as a disinfectant, a platelet aggregation inhibitor, an environmental contaminant, a xenobiotic, a drug allergen and a sensitiser.
Vinkocide BIT 20 D is an organonitrogen heterocyclic compound and an organic heterobicyclic compound.
Vinkocide BIT 20 D is an organic compound with the formula C6H4SN(H)CO.
A white solid, it is structurally related to isothiazole, and is part of a class of molecules called isothiazolinones.
Vinkocide BIT 20 D is widely used as a preservative and antimicrobial.
Vinkocide BIT 20 D is used in personal care products and cosmetics.
Vinkocide BIT 20 D acts as a disinfectant and can be used as a preservative.

Product Benefits
Ideal for use in aqueous and water miscible systems
Broad antimicrobial spectrum against bacteria, fungi and yeasts
Free from formaldehyde, formaldehyde releaser, phenolics, heavy metals or halogens
Excellent chemical stability
Excellent long-term efficacy
Good compatibility with other raw materials

Vinkocide BIT 20 D Chemical Properties
Melting point: 154-158 °C(lit.)
Boiling point: 360°C (rough estimate)
Density: 1.2170 (rough estimate)
Vapor pressure: 0Pa at 25℃
Refractive index: 1.5500 (estimate)
Storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Solubility: Soluble in dichloromethane, dimethyl sulfoxide, methanol.
pka: 10.19±0.20(Predicted)
Color: White to Light yellow to Light orange
Water Solubility: 1.288g/L at 20℃
InChIKey: DMSMPAJRVJJAGA-UHFFFAOYSA-N
LogP: 0.7 at 20℃
CAS DataBase Reference: 2634-33-5
EPA Substance Registry System: Vinkocide BIT 20 D (2634-33-5)

Uses
Vinkocide BIT 20 D is widely used in industry as a preservative in water-based solutions, such as pastes, paints and cutting oils.
Vinkocide BIT 20 D exists at different concentrations in the different Proxel AB, GXL, CRL, XL2, XL, HL, TN, and in Mergal K-10.
Vinkocide BIT 20 D has been widely used in high concentrations for microbial growth control in many domestic and industrial processes, its potential eco-risk should be assessed.
Vinkocide BIT 20 D has a microbicide and a fungicide mode of action.

Vinkocide BIT 20 D is widely used as a preservative, for example in:
emulsion paints, caulks, varnishes, adhesives, inks, and photographic processing solutions
home cleaning and car care products; laundry detergents, stain removers and fabric softeners;
industrial settings, for example in textile spin-finish solutions, leather processing solutions, preservation of fresh animal hides and skins
agriculture in pesticide formulations
gas and oil drilling in muds and packer fluids preservation.: iv 

In paints, Vinkocide BIT 20 D is commonly used alone or as a mixture with methylisothiazolinone.
Typical concentrations in products are 200–400 ppm depending on the application area and the combination with other biocides.
According to a study in Switzerland, 19% of the paints, varnishes and coatings contained Vinkocide BIT 20 D in 2000.
The fraction in adhesives, sealants, plasters and fillers was shown at that time as 25%.
A later study in 2014 shows a dramatic rise in usage, to 95.8% of house paints.

Home cleaning and other care products that are high in water are easily contaminated by microorganisms, so isothiazolinones are often used as a preservatives in these products because they are good at combatting a broad array of bacteria, fungi, and yeasts.

A Swiss investigation found that Vinkocide BIT 20 D is used in concentrations between 50 and 500 ppm in tattooing ink.
According to regulations in the EU and Switzerland, Vinkocide BIT 20 D cannot be used in cosmetics.
However, Vinkocide BIT 20 D is allowed in the United States and Canada.

Contact allergens
Vinkocide BIT 20 D, both an irritant and a skin sensitizer, is widely used in industry as a preservative in water-based solutions such as pastes, paints, and cutting oils.
Occupational dermatitis has been reported mainly due to cutting fluids and greases, in paint manufacturers, pottery moldmakers, acrylic emulsions manufacturers, plumber,printers and lithoprinters, paper makers, analytical laboratory, rubber factory, and employees manufacturing air fresheners.
Vinkocide BIT 20 D is also a preservative in vinyl gloves.

Toxicity evaluation
Vinkocide BIT 20 D, such as 1,2-benzisothiazol-3(2H)-one (BIT), are widely used as biocides for bacterial growth control in many domestic and industrial processes.
Despite their advantages as biocides, they are highly toxic and pose a potential risk to the environment.
Vinkocide BIT 20 D could seriously inhibit the growth of Scenedesmus sp. LX1, Chlorella sp. HQ, and Chlamydomonas reinhardtii with half maximal effective concentrations at 72 h (72h-EC50) of 1.70, 0.41, and 1.16 mg/L, respectively.
The primary inhibition mechanism was the Vinkocide BIT 20 D-induced damage to microalgal photosynthetic systems.

Health hazards
Given sufficient dose and duration, dermal exposure can produce skin sensitization and allergic contact dermatitis, and is classified as an irritant for skin and eyes.
Vinkocide BIT 20 D's low molar mass allows for it to penetrate the epidermis and then react with the skin macromolecules, which causes the irritation.
Benzisothiazolinone has also been linked with Systemic Contact Dermatitis via airborne contact.

In 2012, the Scientific Committee on Consumer Safety in Europe found Vinkocide BIT 20 D's "sensitising potential is of concern.
Sensitisation from related isothiazolinones is an important problem in consumers.
Vinkocide BIT 20 D has occurred because there has been consumer exposure before safe levels of exposure relevant to sensitisation have been established.
Vinkocide BIT 20 D is a skin sensitiser in animal models with potency similar to methylisothiazolinone.
Methylisothiazolinone, at 100 ppm (0.01%) in cosmetic products is causing contact allergy and allergic contact dermatitis in the consumer.
Vinkocide BIT 20 D is known to be a sensitiser in man and has induced sensitisation at circa 20 ppm in gloves."

The opinion further states: "There is no information on what may be safe levels of exposure to benzisothiazolinone in cosmetic products from the point of view of sensitisation.
Until safe levels of exposure have been established, the use of benzisothiazolinone in cosmetic products as a preservative or for other functions cannot be considered safe in relation to sensitisation."

Later, in 2013, researchers published a study that set out to derive the highest concentration of BIT in certain consumer products that would result in exposures below the No Expected Sensitization Induction Level (NESIL); that is, where normal use would yield a dose below the level at which skin sensitization might occur.
The products under consideration were sunscreen, laundry detergent, dish soap, and spray cleaner; by way of calculation they derived BIT NESILs of 0.0075%, 0.035%, 0.035%, 0.021%, respectively.
They then performed a pilot examination via bulk sample analysis of one representative product from each category labelled as containing BIT.
Their findings showed all BIT concentrations well below the derived NESIL, with 0.0009% and 0.0027% for sunscreen and dish soap, respectively, and no detection in the laundry detergent and spray cleaner products, meaning the concentration was at or below the limit of detection of 0.0006%.