TRIMETHYLOLPROPANE TRIISOSTEARATE N° CAS : 68541-50-4 Nom INCI : TRIMETHYLOLPROPANE TRIISOSTEARATE Nom chimique : 2-Ethyl-2-[[(1-oxoisooctadecyl)oxy]methyl]-1,3-propanediyl bis(isooctadecanoate) N° EINECS/ELINCS : 271-347-5 Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent d'entretien de la peau : Maintient la peau en bon état

cas no : 9005-70-3, Emsorb 6903; Glycosperse TO-20; Liposorb TO-20; polyethyleneglycol sorbitan trioleate; Polyoxyethylene (20) sorbitan trioleate; Polyoxyethylene sorbitan trioleate; Polysorbate 85; Protasorb TO-20; Sorbimacrogol trioleate 300; Sorbitan, tri-(9Z)-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.; Sorbitan, tri-9-octadecenoate, poly(oxy-1,2-ethanediyl) derivs.; Sorbitan, trioleate polyoxyethylene deriv.; Tween 85; Ses fonctions (INCI) Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

DESCRIPTION:
Trioctylamine is a clear and colorless chemical compound in the group of aliphatic amines and tertiary amines.
Trioctylamine can easily soluble in chloroform.
Trioctylamine has a form of low melting crystalline mass, and Trioctylamine has the color of white to off-white.

CAS Number: 1116-76-3
EC Number: 214-242-1
IUPAC name: N,N-Di(octyl)octan-1-amine
Molecular Formula: C24H51N


PHYSICAL AND CHEMICAL PROPERTIES OF TRIOCTYLAMINE:
Chemical formula: C24H51N
Molar mass: 353.679 g•mol−1
Density: 0.81 g/cm3[1]
Melting point: −34.6 °C (−30.3 °F; 238.6 K)
Solubility in water: 0.050 mg/l
Viscosity: 7.862 mPa.s
Molecular Weight: 353.7
XLogP3-AA: 10.5
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 21
Exact Mass: 353.402150631
Monoisotopic Mass: 353.402150631
Topological Polar Surface Area: 3.2 Ų C
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 188
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Density: 0.81 g/cm3 (20 °C)
Flash point: 168 °C
Ignition temperature: 315 °C
Melting Point: -39 °C
Vapor pressure: Solubility: Appearance (Clarity): Clear
Appearance (Colour): Pale yellow
Appearance (Form): Liquid
Assay (T): min. 95%
Density (g/ml) @ 20°C: 0.809-0.810
Refractive Index (20°C): 1.448-1.450
Water (KF): max. 0.1%
Melting point: 34 °C
Boiling point: 164-168 °C/0.7 mmHg (lit.) 365-367 °C (lit.)
Density: 0.809 g/mL at 25 °C (lit.)
vapor pressure: refractive index :n20/D 1.449(lit.)
Flash point: >230 °F
storage temp.: Store below +30°C.
solubility: chloroform: 0.1 g/mL, clear, colorless
form: Low Melting Crystalline Mass
pka: 10.08±0.50(Predicted)
Specific Gravity: 0.811 (20/4℃)
Color: White to off-white
Water Solubility: Miscible with chloroform. Immiscible with water.
Sensitive: Air Sensitive
Trioctylamine is a clear colorless method and can be converted to the amine hydrochloride etherate which is recrystallized four times from diethyl ether at -30 °C.
Neutralization of this salt regenerates the free amine which distilled under high vacuum.
Trioctylamine has melting point of −34 °C; boiling point of 164-168 °C at 0.7 mmHg and 365-367 °C at 1 atm; density of 0.810 g/mL at 20 °C; refractive index of n20/D 1.449; flash point of >230 °F; storage temperature is below 30 °C.

Trioctylamine is miscible with chloroform but immiscible with water.
Trioctylamine is air sensitive.
There is a safety hazard for this chemical compound.

Trioctylamine can cause skin irritation, serious eye irritation, and respiratory irritation.
Trioctylamine can damage fertility or the unborn child and cause damage to organs through prolonged or repeated exposure.
Trioctylamine is very toxic to aquatic life with long lasting effects.


PRODUCTION METHOD OF TRIOCTYLAMINE:
Ammoniation is carried out in the presence of aluminum trichloride catalyst using n-octanol as raw material.
The reaction is carried out in a condensation kettle, ammonia is introduced into the kettle, and the reaction is carried out at 400 ℃.
Then remove the excess n-octanol and filter out the catalyst to obtain the finished trioctylamine.
Raw material consumption (kg/t) n-octanol 1217 trialumina 685.


APPLICATION OF TRIOCTYLAMINE:
Trioctylamine is used to extract organic acids such as succinic acid and acetic acid, and also precious metals.
A formulation containing metoxuron mixed with an emulsion containing trioctylamine 50%, atlox 4851 B 15%, and isopropanol 35% was active as a potato defoliant.
Trioctylamine can be used to extract monocarboxylic acid for equilibria and correlation of apparent reactive equilibrium constant.

Liquid-liquid equilibria for aqueous solutions of carboxylic acids with trioctylamine in various diluents was determined at various trioctylamine concentrations.
The loading of trioctylamine for a given carboxylic acid depends on the nature of the solute and its concentration.
The apparent extraction equilibrium constants depend on the hydrophobicity and acidity of the carboxylic acid, as well as the specific basicity of trioctylamine.
Trioctylamine production can be used as a mineral extraction reagent, an extractant for reactor fuel processing, and its use as an extractant for identification of dyes may result in its release to the environment through various waste streams.

USES OF TRIOCTYLAMINE:
Trioctylamine is used as a precious metal extractant.
In the metallurgical industry, Trioctylamine is used to extract and separate cobalt, nickel, actinides and lanthanides.
Trioctylamine is used in organic synthesis.

Trioctylamine is a heat-resistant, solvent-resistant, polymeric rubber antioxidant.
Trioctylamine is the intermediate amine extractant for synthesizing NAPM.
Trioctylamine has good extraction performance for actinides such as thorium and uranium.

Moreover, Trioctylamine can extract and separate non-ferrous metals, rare and scattered metals and platinum elements in different systems.
Trioctylamine is used in the production of phase transfer catalysts, rubber additives and corrosion inhibitors.

Trioctylamine is used as surfactant and extractant.
Tri-n-octylamine is used as an extractant for organic acids and precious metals.
Tri-n-octylamine is used as an extractant for organic acids like trichloroacetic acid, succinic acid, acetic acid and precious metals.
Trioctylamine is also used as a solvent and an intermediate in the manufacture of pharmaceuticals.

Further, Trioctylamine is employed in the preparation of quaternary ammonium compounds, agrochemicals, surfactants, lubricant additives, corrosion inhibitors, vulcanization accelerators and dyes.
Trioctylamine is used as an extractant for organic acids (such as TCA, succinic acid, and acetic acid), and precious metals.

SAFETY INFORMATION ABOUT TRIETHYLAMINE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


SYNONYMS OF TRIOCTYLAMINE:
MeSH Entry Terms:
tri-N-octylamine
trioctylamine
Depositor-Supplied Synonyms:
Trioctylamine
1116-76-3
TRI-N-OCTYLAMINE
Tricaprylamine
Tricaprylylamine
1-Octanamine, N,N-dioctyl-
Tri-n-caprylylamine
Farmin 08
Alamine 336
Alamine 336S
N,N-dioctyloctan-1-amine
Alamine 3365
Alamine 308
336S
NSC 11034
TOA
NSC-11034
I40965UY86
HSDB 5786
EINECS 214-242-1
BRN 1210618
trioctyl amine
AI3-17998
UNII-I40965UY86
Trioctylamine, 98%
1-Octanamine,N-dioctyl-
SCHEMBL36609
TRICAPRYLAMINE [HSDB]
N,N-Dioctyl-1-octanamine #
CHEMBL3222022
DTXSID3047635
WLN: 8N8&8
AMY21907
NSC11034
ZINC6920427
MFCD00009560
AKOS015915431
CS-W011849
SB83655
Trioctylamine, purum, >=98.0% (GC)
BS-14388
Trioctylamine, SAJ first grade, >=99.0%
FT-0600026
FT-0655520
I0362
T0502
EN300-74244
D70441
A802393
W-108670
Q27280370
Z1167043198

TRIOLÉATE DE SORBITAN, cas no : 26266-58-0; Span 85 (=Sorbitan Trioleate); Span 85; Span 85V, Anhydro-D-glucitol trioleate; Nom INCI : SORBITAN TRIOLEATE; Nom chimique : Anhydro-D-glucitol trioleate; N° EINECS/ELINCS : 247-569-3; Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

TRIOLEYL CITRATE, N° CAS : 175831-77-3, Nom INCI : TRIOLEYL CITRATE, Nom chimique : 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tri-9-octadecenyl ester (all-Z)-, Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau, Agent plastifiant : Adoucit et rend souple une autre substance qui autrement ne pourrait pas être facilement déformée, dispersée ou être travaillée, Agent d'entretien de la peau : Maintient la peau en bon état

Triolein is a symmetrical triglyceride derived from glycerol and three units of the unsaturated fatty acid oleic acid.
Triolein, known widely as Glyceryl trioleate, is an oily liquid that is a main constituent of some nondrying oils and fats.
Triolein is also known as glyceryl trioleate and is one of the two components of Lorenzo's oil.

CAS Number: 122-32-7
EC Number: 204-534-7
Chemical formula: C57H104O6
Molecular Weight: 885.43

(9Z)9-Octadecenoic acid 1,2,3-propanetriyl ester, 1,2,3-Tri(cis-9-octadecenoyl)glycerol, Glycerol trioleate, Glycerol triolein, Oleic acid triglyceride, Oleic triglyceride, TG(18:1(9Z)/18:1(9Z)/18:1(9Z)), Triolein, GLYCERYL TRIOLEATE, Glycerol trioleate, 122-32-7, Oleic triglyceride, Olein, Trioleoylglycerol, Glycerol triolein, Oleic acid triglyceride, Trioleoylglyceride, Glycerin trioleate, Oleyl triglyceride, Raoline, Glyceryl-1,2,3-trioleate, Aldo TO, Emery 2423, Olein, tri-, Emery oleic acid ester 2230, Glycerol, tri(cis-9-octadecenoate), 1,2,3-Propanetriyl trioleate, HSDB 5594, Triglyceride OOO, Edenor NHTi-G, Kaolube 190, sn-Glyceryl trioleate, 1,2,3-tri-(9Z-octadecenoyl)-glycerol, Actor LO 1, Kemester 1000, UNII-O05EC62663, Emerest 2423, 9-Octadecenoic acid (Z)-, 1,2,3-propanetriyl ester, 9-Octadecenoic acid (9Z)-, 1,2,3-propanetriyl ester, Estol 1433, Radia 7363, 1,2,3-Tri(cis-9-octadecenoyl)glycerol, 1,2,3-tri-oleoyl-glycerol, 1,2,3-Propanetriol tri(9-octandecenoate), CHEBI:53753, TG(18:1(9Z)/18:1(9Z)/18:1(9Z)), 2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl (Z)-octadec-9-enoate, 9-Octadecenoic acid, 1,2,3-propanetriyl ester, MFCD00137563, O05EC62663, propane-1,2,3-triyl (9Z,9'Z,9''Z)tris-octadec-9-enoate, glycerine trioleate, 1,3-bis[(9Z)-octadec-9-enoyloxy]propan-2-yl (9Z)-octadec-9-enoate, TG 54:3, (9Z)9-Octadecenoic acid 1,2,3-propanetriyl ester, EINECS 204-534-7, CCRIS 8687, tri-Olein, 9-Octadecenoic-9,10-t2 acid, 1,2,3-propanetriyl ester, (Z,Z,Z)- (9CI), C57H104O6, triolein C18:1, Triolein, tech grade, GLYCERYLTRIOLEATE, tri(cis-9-octadecenoate), Epitope ID:117714, 1,2,3-propanetriyl ester, EC 204-534-7, Glyceryl trioleate, ~65% SCHEMBL23730, Glyceryl trioleate, >=99%, 9-Octadecenoic acid (9Z)-, 1,1',1''-(1,2,3-propanetriyl) ester, CHEMBL4297656, DTXSID3026988, HY-N1981, Triolein, [9,10-3H(N)]-, LMGL03010250, s3590, ZINC85545180, AKOS024437536, DB13038, Glyceryl trioleate, >=97.0% (TLC), 1,2,3-tri-(9Z-octadecenoyl)-sn-glycerol, CS-0018302, G0089, V0255, Glyceryl trioleate, technical, >=60% (GC), (Z)-1,2,3-propanetriyl ester 9-Octadecenoate, (9Z)-1,2,3-propanetriyl ester 9-Octadecenoate, Glyceryl trioleate, analytical reference material, Q413929, (9Z)-1,2,3-propanetriyl ester 9-Octadecenoic acid, (Z)-1,2,3-propanetriyl ester 9-Octadecenoic acid, (Z)-9-Octadecenoic acid, 1,2,3-propanetriyl ester, J-004788, propane-1,2,3-triyl tris[(9Z)-octadec-9-enoate], AC7B54B8-0E34-455F-A1E0-442F3ECD69EA, Triolein, European Pharmacopoeia (EP) Reference Standard, TG(18:1(9Z)/18:1(9Z)/18:1(9Z))[iso], UNII-2GQR19D8A4 component PHYFQTYBJUILEZ-IUPFWZBJSA-N, UNII-4PC054V79P component PHYFQTYBJUILEZ-IUPFWZBJSA-N, (9Z)-1,1',1''-(1,2,3-propanetriyl) ester 9-Octadecenoate, (9Z)-1,1',1''-(1,2,3-propanetriyl) ester 9-Octadecenoic acid, 9-octadecenoic acid, 1,2,3-propanetriyl ester, (9Z,9'Z,9''Z)-, Triolein (18:1 TG), 1,2,3-tri-(9Z-octadecenoyl)-glycerol, neat oil, (9Z)9-Octadecenoic acid 1,2,3-propanetriyl ester, (9Z,9'Z,9''Z)Tris(-9-octadécénoate) de 1,2,3-propanetriyle, 1,2,3-Propanetriyl (9Z,9'Z,9''Z)tris(-9-octadecenoate), 1,2,3-Propantriyl-(9Z,9'Z,9''Z)tris(-9-octadecenoat), 1,2,3-tri-(9Z-octadecenoyl)-sn-glycerol, 1,2,3-Tri(cis-9-octadecenoyl)glycerol, 1,2,3-Trioleoyl Glycerol, 122-32-7, 204-534-7, 9-Octadecenoic acid (9Z)-, 1,2,3-propanetriyl ester, 9-Octadecenoic acid (Z)-, 1,2,3-propanetriyl ester, 9-Octadecenoic acid, 1,2,3-propanetriyl ester, (9Z,9'Z,9''Z)-, Glycerin trioleate, Glycerine trioleate, Glycerol trioleate, Glycerol triolein, Glycerol, tri(cis-9-octadecenoate), glyceryl trioleate, Glyceryl-1,2,3-trioleate, MFCD00137563, Oleic acid triglyceride, Oleic triglyceride, Olein, tri-, Propane-1,2,3-triyl (9Z,9'Z,9''Z)tris-octadec-9-enoate, Triolein, (9Z)-1,1',1''-(1,2,3-propanetriyl) ester 9-Octadecenoate, (9Z)-1,1',1''-(1,2,3-propanetriyl) ester 9-Octadecenoic acid, (9Z)-1,2,3-propanetriyl ester 9-Octadecenoate, (9Z)-1,2,3-propanetriyl ester 9-Octadecenoic acid, (9Z)-9-Octadecenoic acid 1,2,3-propanetriyl ester, (Z)-1,2,3-propanetriyl ester 9-Octadecenoate, (Z)-1,2,3-propanetriyl ester 9-Octadecenoic acid, (Z)-9-Octadecenoic acid, 1,2,3-propanetriyl ester, 1,2,3-Propanetriol tri(9-octandecenoate), 1,2,3-Propanetriyl trioleate, 1,2,3-tri-(9Z-octadecenoyl)-glycerol, 1,2,3-Trioleoyl-rac-glycerol, 1,3-bis[(9Z)-octadec-9-enoyloxy]propan-2-yl (9Z)-octadec-9-enoate, 124330-00-3, 1257300-52-9, 1-oleoyl-2-oleoyl-3-oleoyl-glycerol, 2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl (Z)-octadec-9-enoate, 24016-60-2, 247-038-6, 25496-72-4, 41755-78-6, 9-Octadecenoic acid, 1,2,3-propanetriyl ester, Aldo TO, Edenor NHTi-G, GLYCERYL OLEATE, Kaolube 190, olein, Oleyl triglyceride, propane-1,2,3-triyl trioleate, propane-1,2,3-triyl tris[(9Z)-octadec-9-enoate], Raoline, sn-Glyceryl trioleate, TAG(18:1,18:1,18:1), TAG(54:3), TG(54:3), Tracylglycerol(54:3), Triglyceride, trioctadecenoin, Tri-Olein, Triolein (18:1 TG), Triolein, [9,10-3H(N)]-, trioleína, Trioleoylglyceride, Trioleoylglycerol

Triolein is derived from glycerol.
Triolein is composed of three oleic acid units and is an unsaturated triglyceride.

Triolein, known widely as Glyceryl trioleate, is an oily liquid that is a main constituent of some nondrying oils and fats.
Triolein occurs in many natural fats and oils, including sunflower oil, palm oil, cacao butter, and, most notably, olive oil.

In 1941, Thomas P. Hilditch and L. Maddison at the University of Liverpool (UK) crystallized olive oils from Italy and Palestine at temperatures down to –30 °C to resolve them into several components.
They found that olive oil from Palestine contained ≈30% triolein, whereas the Italian oil contained only ≈5%.

Eight years later, M. L. Meara, also at Liverpool, resolved cacao butter into 11 fractions “by exhaustive crystallization”.
For his efforts, only 1.1% of the fat turned out to be Triolein.
From 1940 to 1961, several chemists devised syntheses of triolein by esterifying glycerol and oleic acid.

Sacramental uses of olive oil are strongly connected to Christian and Jewish traditions, especially Hanukkah.

During the period of the Hanukkah story (168 BCE), only pure olive oil blessed by the high priest could be used to light the Temple menorah, which had to be lit continuously.
After their victorious battle over the Syrian Greeks, the Maccabees could find only enough holy oil to last for one day.
The Hanukkah miracle is that the oil lasted eight days, enough time for more oil to be prepared and sanctified.

Olive oil was the major component of anointing oils and lamp fuel that date to biblical times.
Kings were anointed with oil as a mark of their official status; and one title for Jesus is the Anointed One.
References are found throughout the Hebrew and Christian scriptures about the use of oil as part of fasting and healing rituals.

Triolein is a symmetrical triglyceride derived from glycerol and three units of the unsaturated fatty acid oleic acid.
Most triglycerides are unsymmetrical, being derived from mixtures of fatty acids.
Triolein represents 4–30% of olive oil.

Triolein is also known as glyceryl trioleate and is one of the two components of Lorenzo's oil.

The oxidation of triolein is according to the formula:
C57H104O6 + 80 O2 → 57 CO2 + 52 H2O

This gives a respiratory quotient of 57/80 or 0.7125.
The heat of combustion is 8,389 kcal (35,100 kJ) per mole or 9.474 kcal (39.64 kJ) per gram.
Per mole of oxygen Triolein is 104.9 kcal (439 kJ).

Triolein is derived from glycerol.
Triolein is composed of three oleic acid units and is an unsaturated triglyceride.

Triolein (glycerol trielaidate, or trielaidin) is a triglyceride formed by esterification of the three hydroxy groups of glycerol with elaidic acid.

Triolein or Glyceryl trioleate is a triglyceride formed by esterification of the three hydroxy groups of glycerol with oleic acid.
Triolein is one of the two components of Lorenzo's oil.

Triolein has a role as a plant metabolite.
Triolein derives from an oleic acid.
Triolein can be found as a clear colorless liquid.

Constituent of olive oil and other vegetable oils TG(18:1(9Z)/18:1(9Z)/18:1(9Z)) or Triolein is a monoacid triglyceride.
Triglycerides (TGs) are also known as triacylglycerols or triacylglycerides.

TGs are fatty acid triesters of glycerol and may be divided into three general types with respect to their acyl substituents.
They are simple or monoacid if they contain only one type of fatty acid, diacid if they contain two types of fatty acids and triacid if three different acyl groups.

Chain lengths of the fatty acids in naturally occurring triglycerides can be of varying lengths and saturations but 16, 18 and 20 carbons are the most common.
TGs are the main constituent of vegetable oil and animal fats.

TGs are major components of very low density lipoprotein (VLDL) and chylomicrons, play an important role in metabolism as energy sources and transporters of dietary fat.
They contain more than twice the energy (9 kcal/g) of carbohydrates and proteins.

In the intestine, triglycerides are split into glycerol and fatty acids (this process is called lipolysis) (with the help of lipases and bile secretions), which can then move into blood vessels.
The triglycerides are rebuilt in the blood from their fragments and become constituents of lipoproteins, which deliver the fatty acids to and from fat cells among other functions.

Various tissues can release the free fatty acids and take them up as a source of energy.
Fat cells can synthesize and store triglycerides.

When the body requires fatty acids as an energy source, the hormone glucagon signals the breakdown of the triglycerides by hormone-sensitive lipase to release free fatty acids.
As the brain cannot utilize fatty acids as an energy source, the glycerol component of triglycerides can be converted into glucose for brain fuel when Triolein is broken down.

TAGs can serve as fatty acid stores in all cells, but primarily in adipocytes of adipose tissue.
The major building block for the synthesis of triacylglycerides, in non-adipose tissue, is glycerol.

Adipocytes lack glycerol kinase and so must use another route to TAG synthesis.
Specifically, dihydroxyacetone phosphate (DHAP), which is produced during glycolysis, is the precursor for TAG synthesis in adipose tissue. DHAP can also serve as a TAG precursor in non-adipose tissues, but does so to a much lesser extent than glycerol.

The use of DHAP for the TAG backbone depends on whether the synthesis of the TAGs occurs in the mitochondria and ER or the ER and the peroxisomes.
The ER/mitochondria pathway requires the action of glycerol-3-phosphate dehydrogenase to convert DHAP to glycerol-3-phosphate. Glycerol-3-phosphate acyltransferase then esterifies a fatty acid to glycerol-3-phosphate thereby generating lysophosphatidic acid.

The ER/peroxisome reaction pathway uses the peroxisomal enzyme DHAP acyltransferase to acylate DHAP to acyl-DHAP which is then reduced by acyl-DHAP reductase.
The fatty acids that are incorporated into TAGs are activated to acyl-CoAs through the action of acyl-CoA synthetases.

Two molecules of acyl-CoA are esterified to glycerol-3-phosphate to yield 1,2-diacylglycerol phosphate (also known as phosphatidic acid). The phosphate is then removed by phosphatidic acid phosphatase (PAP1), to generate 1,2-diacylglycerol.
This diacylglycerol serves as the substrate for addition of the third fatty acid to make TAG.

Intestinal monoacylglycerols, derived from dietary fats, can also serve as substrates for the synthesis of 1,2-diacylglycerols.
Triolein is a triglyceride and unsaturated fat formed from oleic acid.
Triolein is found in fats and oils, almond, and peach.

Applications of Triolein:

Triolein has been used:
Triolein used as an experimental diet along with fat-free basal mix and corn oil and then to access the dietary fat absorption among mice

Triolein used as an interfering substance to test Triolein effect on human serum in the approach to develop rapid enzyme immunoassay for the detection of retinol-binding protein
Triolein used as a standard in the determination of triglyceride concentration, colorimetrically using liver tissue sample from cows

Uses of Triolein:
A major component of oils and fats, e.g., olive oil.
Triolein used as lubricant (e.g. for cosmetics, drugs, and textiles), emulsifier (e.g. for water/oil mixtures), intermediate for radioactive iodine derivatives, and plasticizer.
Triolein used in sweet almond oil for medicines and cosmetics.

Industry Uses:
Intermediates
Lubricants and lubricant additives

Consumer Uses:
Lubricants and greases
Non-TSCA use

Therapeutic Uses:
The aim of this study was to identify asymptomatic boys with X-linked adrenoleukodystrophy who have a normal magnetic resonance image (MRI), and to assess the effect of 4:1 Triolein-glyceryl trierucate (Lorenzo's oil) on disease progression.
Eighty-nine boys (mean +/- SD baseline age, 4.7 +/- 4.1 years; range, 0.2-15 years) were identified by a plasma very long-chain fatty acids assay used to screen at-risk boys.

All were treated with Lorenzo's oil and moderate fat restriction.
Plasma fatty acids and clinical status were followed for 6.9 +/- 2.7 years.

Changes in plasma hexacosanoic acid levels were assessed by measuring the length-adjusted area under the curve, and a proportional hazards model was used to evaluate association with the development of abnormal MRI results and neurological abnormalities.
Of the 89 boys, 24% developed MRI abnormalities and 11% developed both neurological and MRI abnormalities.

Abnormalities occurred only in the 64 patients who were aged 7 years or younger at the time therapy was started.
There was significant association between the development of MRI abnormalities and a plasma hexacosanoic acid increase.

(For a 0.1-ug/mL increase in the length-adjusted area under the curve for the hexacosanoic acid level, the hazard ratio for incident MRI abnormalities in the whole group was 1.36; P = .01; 95% confidence interval, 1.07-1.72.)
Results for patients aged 7 years or younger were similar (P = .04).

In this single-arm study, hexacosanoic acid reduction by Lorenzo's oil was associated with reduced risk of developing MRI abnormalities.
We recommend Lorenzo's oil therapy in asymptomatic boys with X-linked adrenoleukodystophy who have normal brain MRI results.

X-linked adrenoleukodystrophy (X-ALD) is an inherited disorder of peroxisomal metabolism, biochemically characterized by deficient beta-oxidation of saturated very long chain fatty acids (VLCFA).
The consequent accumulation of these fatty acids in different tissues and in biological fluids is associated with a progressive central and peripheral demyelination, as well as with adrenocortical insufficiency and hypogonadism.

Seven variants of this disease have been described, cerebral childhood being the most frequent.
The recommended therapy consists of the use of the glyceroltrioleate/glyceroltrierucate mixture known as Lorenzo's Oil (LO), combined with a VLCFA-poor diet, but only in asymptomatic patients will this treatment prevent the progression of the symptomatology.

In the present study we evaluated the biochemical course of patients with cerebral childhood (CCER) and asymptomatic clinical forms of X-ALD treated with LO associated with a VLCFA-restricted diet.
We observed that hexacosanoic acid plasma concentrations and hexacosanoic/docosanoic ratio were significantly reduced in CCER patients during treatment when compared with diagnosis.

Hexacosanoic acid plasma level was significantly reduced when compared with that at diagnosis and achieved the normal levels only in asymptomatic patients under LO treatment.
In asymptomatic patients the magnitude of hexacosanoic acid decrease was higher than that of the CCER patients.

These results show the good biochemical response of LO treatment in asymptomatic X-ALD patients.
Triolein is possible to suppose that this could be correlated with the prevention of the appearance of neurological signals in this group of patients treated with LO.

Investigated the possible therapeutic effect of decreasing plasma levels of very-long-chain fatty acids (C26:0) with a synthetic oil containing trioleate and trielucate (Lorenzo's oil) as well as increasing docosahexaenoic acid (DHA) in red blood cells (RBC) with DHA ethyl ester in four patients with Zellweger syndrome.
Investigated serial changes of plasma C26:0 levels and DHA levels in RBC membranes by gas-liquid chromatography/mass spectrometry (GC/MS). After death, the fatty acid composition of each patient's cerebrum and liver was studied.

Dietary administration of Lorenzo's oil diminished plasma C26:0 levels.
Earlier administration of Lorenzo's oil was more effective and the response did not depend on the duration of administration.

DHA was incorporated into RBC membrane lipids when administrated orally, and Triolein level increased for several months.
The final DHA level was correlated with the duration of administration and was not related to the timing of initiation of treatment.

DHA levels in the brains and livers of treated patients were higher than in untreated patients.
Early initiation of Lorenzo's oil and the long-term administration of DHA may be useful for patients with Zellweger syndrome.

Pharmacology and Biochemistry of Triolein:

Absorption, Distribution and Excretion:
In the small intestine, most triglycerides are split into monoglycerides, free fatty acids, and glycerol, which are absorbed by the intestinal mucosa.
Within the epithelial cells, resynthesized triglycerides collect into globules along with cholesterol and phospholipids and are encased in a protein coat as chylomicrons.

Chylomicrons are transported in the lymph to the thoracic duct and eventually to the venous system.
The chylomicrons are removed from the blood as they pass through the capillaries of adipose tissue.
Fat is stored in adipose cells until Triolein is transported to other tissues as free fatty acids which are used for cellular energy or incorporated into cell membranes.

When (14)C-labeled long-chain triglycerides are administered intravenously, 25% to 30% of the radiolabel is found in the liver within 30 to 60 minutes, with less than 5% remaining after 24 hours.
Lesser amounts of radiolabel are found in the spleen and lungs.

After 24 hours, nearly 50% of the radiolabel has been expired in carbon dioxide, with 1% of the carbon label remaining in the brown fat.
The concentration of radioactivity in the epididymal fat is less than half that of the brown fat.

Human Metabolite Information of Triolein:

Cellular Locations:
Extracellular
Membrane

Manufacturing Methods of Triolein:
Preparation by esterification of oleic acid.

Triolein is the predominating constituent in expressed almond oil, in lard oil, & in many of the more fluid animal oils & those of vegetable origin.
Triolein is separated & purified by cold expression, the other constituents being retained by their lack of fluidity at low temp.

The triglyceride of oleic acid, occurring in most fats and oils.
Triolein constitutes 70-80% of olive oil

Reaction of refined oil, eg, olive oil, with glycerol followed by fractional distillation; reaction of oleic acid with glycerol; separation & purification from fats & oils as liquid phase by cold expression.

General Manufacturing Information of Triolein:

Industry Processing Sectors:
Textiles, apparel, and leather manufacturing
Transportation equipment manufacturing

Stable water-in-oil emulsions (with a high water content) for cosmetics are prepared by dissolving the neutral oil & 5-50% lecithin emulsifier at less than or equal to 70 °C, cooling to 0-12 °C, & adding water to a concentration of 50-83%.
The neutral oil can be a glycerol, such as Triolein, or propylene glycol ester of a carbon 8-12 fatty acid or isopropyl myristate.

Ecological Information of Triolein:

Environmental Fate/Exposure Summary of Triolein:
Triolein's production and use as textile lubricant and plasticizer may result in Triolein release to the environment through various waste streams.
Triolein is found in cacao butter and accounts for 70-80% of olive oil.

If released to air, an estimated vapor pressure range of 5X10-5 mm Hg to 1.1X10-9 mm Hg at 25 °C indicates triolein may exist in both the vapor and particulate phases in the atmosphere.
Vapor-phase triolein will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 1.7 hours.

Vapor-phase triolein will also be degraded in the atmosphere by reaction with ozone; the half-life for this reaction in air is estimated to be 0.7 hours.
Particulate-phase triolein will be removed from the atmosphere by wet or dry deposition.

If released to soil, triolein is expected to have no mobility based upon an estimated Koc of 1X10+10.
Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law constant of 9.6X10-4 atm-cu m/mole; however, soil adsorption will attenuate the importance of volatilization.

14C-Labeled triolein biodegraded to CO2 at a rate of 63.5% to 84% over 140 days in a sewage sludge-amended soil, suggesting that biodegradation may occur in the soil environment.
If released into water, triolein is expected to adsorb to suspended solids and sediment based upon the estimated Koc.

Volatilization from water surfaces is expected to be an important fate process based upon this compound's estimated Henry's Law constant.
Estimated volatilization half-lives for a model river and model lake are 11 hours and 13 days, respectively.

However, volatilization from water surfaces is expected to be attenuated by adsorption to suspended solids and sediment in the water column.
The estimated volatilization half-life from a model pond is 5.1X10+5 years if adsorption is considered.

An estimated BCF of 3.2 suggests the potential for bioconcentration in aquatic organisms is low.
An estimated base-catalyzed second-order hydrolysis rate constant of 0.15 L/mole-sec corresponds to half-lives of 1.5 years and 55 days at pH values of 7 and 8, respectively.

In respirometry tests, triolein had a biodegradation rate constant of 0.0025 per hour which corresponds to a half-life of 11.6 days; bioavailability was restricted due to the presence of double bonds and an autoxidation process occurring in the allylic chains resulting in the production of hydroperoxides, but the non-oxidized fractions were readily mineralized.
Occupational exposure to triolein may occur through dermal contact with this compound at workplaces where triolein is produced or used. Monitoring data indicate that the general population may be exposed to triolein via ingestion of food products containing triolein as well as via dermal contact with consumer products containing triolein.

Stability and Reactivity of Triolein:

Hazardous Reactivities and Incompatibilities of Triolein:
Triolein (major skin lipid) was irradiated with 300-nm ultraviolet (UV) light, and the conditions for exposure approximated those at the skin surface exposed to sunlight.
Using gas chromatography, the irradiated samples were analyzed for the presence of acrolein, formaldehyde, and acetaldehyde.

The maximum amount of acrolein (1.05 nmol/mg Triolein) was formed after 6 hours of irradiation.
Maximum amounts of formaldehyde (6 nmol/mg Triolein) and acetaldehyde (2.71 nmol/mg Triolein) were formed after 12 hours of irradiation.

Disposal Methods of Triolein:
The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination.
Recycle any unused portion of the material for Triolein approved use or return Triolein to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Antidote and Emergency Treatment of Triolein:

Immediate first aid:
Ensure that adequate decontamination has been carried out.
If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained.

Perform CPR if necessary.
Immediately flush contaminated eyes with gently flowing water.

Do not induce vomiting.
If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration.

Keep patient quiet and maintain normal body temperature.
Obtain medical attention.

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed).
Suction if necessary.
Watch for signs of respiratory insufficiency and assist ventilations if needed.

Administer oxygen by nonrebreather mask at 10 to 15 L/min.
Monitor for pulmonary edema and treat if necessary.

Monitor for shock and treat if necessary.
Anticipate seizures and treat if necessary.

For eye contamination, flush eyes immediately with water.
Irrigate each eye continuously with 0.9% saline (NS) during transport.

Do not use emetics.
For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool.
Cover skin burns with dry sterile dressings after decontamination.

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress.
Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema.

Consider administering a beta agonist such as albuterol for severe bronchospasm.
Monitor cardiac rhythm and treat arrhythmias as necessary.

Use 0.9% saline (NS) or lactated Ringer's if signs of hypovolemia are present.
For hypotension with signs of hypovolemia, administer fluid cautiously.

Watch for signs of fluid overload.
Treat seizures with diazepam or lorazepam.
Use proparacaine hydrochloride to assist eye irrigation.

Identifiers of Triolein:
CAS Number: 122-32-7
ChEBI: CHEBI:53753
ChemSpider: 4593733
ECHA InfoCard: 100.004.123
MeSH: Triolein
PubChem CID: 5497163
UNII: O05EC62663
CompTox Dashboard (EPA): DTXSID3026988
InChI:
InChI=1S/C57H104O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27- check
Key: PHYFQTYBJUILEZ-IUPFWZBJSA-N check
InChI=1/C57H104O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-
Key: PHYFQTYBJUILEZ-IUPFWZBJBN
SMILES: O=C(OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC)CCCCCCC\C=C/CCCCCCCC

Properties of Triolein:
Biological source: plant (sunflower)
Quality Level: 200
Assay: ≥99%
Form: oil
bp: 235-240 °C/18 mmHg (lit.)
Density: 0.91 g/mL (lit.)
Functional group: ester
Shipped in: ambient
Storage temp.: −20°C
SMILES string: [H]C(COC(CCCCCCC/C=C\CCCCCCCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
InChI: 1S/C57H104O6/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-55(58)61-52-54(63-57(60)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3)53-62-56(59)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2/h25-30,54H,4-24,31-53H2,1-3H3/b28-25-,29-26-,30-27-
InChI key: PHYFQTYBJUILEZ-IUPFWZBJSA-N

Chemical formula: C57H104O6
Molar mass: 885.432 g/mol
Appearance: Colourless viscous liquid
Density: 0.9078 g/cm3 at 25 °C
Melting point: 5 °C; 41 °F; 278 K
Boiling point: 554.2 °C; 1,029.6 °F; 827.4 K
Solubility: Chloroform 0.1g/mL

Molecular Weight: 885.4
XLogP3-AA: 22.4
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 53
Exact Mass: 884.78329103
Monoisotopic Mass: 884.78329103
Topological Polar Surface Area: 78.9 Ų
Heavy Atom Count: 63
Complexity: 1010
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 3
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Hazards of Triolein:
Flash point: 302.6 °C (576.7 °F; 575.8 K)

Thermochemistry of Triolein:
Std enthalpy of formation (ΔfH⦵298): 1.97*105 kJ/kmol
Gibbs free energy (ΔfG˚): -1.8*105 kJ/kmol
Std enthalpy of combustion (ΔcH⦵298): 8,389 kcal (35,100 kJ) /mole

Specifications of Triolein:
Density: 0.9130g/mL
Color: Colorless to Yellow
Boiling Point: 235.0°C to 240.0°C (18.0mmHg)
Assay Percent Range: 98.5% min. (GC)
Infrared Spectrum: Authentic
Linear Formula: (C17H33COOCH2)2CHOCOC17H33
Beilstein: 02,IV,1664
Packaging: Glass bottle
Merck Index: 15,9904
Refractive Index: 1.4680 to 1.4700
Quantity: 1mL
Solubility Information: Solubility in water: insoluble in water. Other solubilities: soluble in chloroform, ether, ccl4, slightly soluble in alcohol
Specific Gravity: 0.913
Formula Weight: 885.45
Physical Form: Liquid
Percent Purity: 99%
Chemical Name or Material: Glycerine trioleate

Names of Triolein:

Preferred IUPAC name:
Propane-1,2,3-triyl tri[(9Z)-octadec-9-enoate]

TRIOLEYL PHOSPHATE, N° CAS : 3305-68-8, Nom INCI : TRIOLEYL PHOSPHATE, Nom chimique : Trioleyl phosphate, N° EINECS/ELINCS : 221-983-4. Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau. Agent plastifiant : Adoucit et rend souple une autre substance qui autrement ne pourrait pas être facilement déformée, dispersée ou être travaillée, Agent d'entretien de la peau : Maintient la peau en bon état. Produits qui en contiennent

TRIPEPTIDE-10 Nom INCI : TRIPEPTIDE-10 Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état

Tripalmitin is a triglyceride composed of three palmitic acid molecules esterified to a glycerol backbone.
Tripalmitin is a white, waxy solid with a powdery texture.
Tripalmitin is odorless and tasteless.

CAS number: 555-44-2
EC number: 209-008-0



APPLICATIONS


Tripalmitin (glycerin tripalmitate) finds applications in various industries. Here are some of its key applications:

Food Industry:
Tripalmitin is used as a food additive and ingredient.
Tripalmitin functions as a texturizer, stabilizer, and emulsifier in processed foods, baked goods, confectionery, and dairy products.

Cosmetics and Skincare:
Tripalmitin is used in cosmetics and skincare products as an emollient, moisturizer, and thickening agent.
Tripalmitin helps improve the texture, spreadability, and stability of creams, lotions, lip balms, and other personal care formulations.

Pharmaceuticals:
Tripalmitin is employed in the pharmaceutical industry for various applications. It is used as a carrier for lipophilic drugs, facilitating their delivery and absorption.
Tripalmitin can be incorporated into solid oral dosage forms, transdermal patches, and suppositories.

Industrial Lubricants:
Tripalmitin is utilized in the production of industrial lubricants and metalworking fluids due to its lubricating properties.
Tripalmitin helps reduce friction and wear in machinery and improves overall performance.

Candle Making:
Tripalmitin is a common ingredient in candle making.
Tripalmitin serves as a wax component, contributing to the candle's structure, hardness, and burn characteristics.

Personal Care Products:
Tripalmitin is used in various personal care products, including lipsticks, lip balms, sunscreens, and hair care formulations.
Tripalmitin provides texture, moisturizing properties, and stability to these products.

Coatings and Polishes:
Tripalmitin can be found in coatings, polishes, and wax-based products.
Tripalmitin enhances the gloss, smoothness, and protective properties of surfaces, such as wood, leather, and metal.

Industrial Applications:
Tripalmitin is employed in industrial applications, such as mold release agents, plasticizers, and lubricant additives.
Tripalmitin helps reduce friction, improve flow, and enhance the performance of various materials and processes.

Research and Development:
Tripalmitin is commonly used in laboratories for research and development purposes.
Tripalmitin serves as a model compound to study lipid metabolism, drug delivery systems, and formulation development.

Nutraceuticals:
Tripalmitin is used in the formulation of nutraceutical products, including dietary supplements and functional foods.
Tripalmitin provides a source of energy and serves as a carrier for fat-soluble vitamins and bioactive compounds.

Animal Feed:
Tripalmitin can be incorporated into animal feed formulations as an energy source for livestock and poultry.
Tripalmitin helps improve the caloric density of the feed and supports healthy growth.

Biomedical Research:
Tripalmitin is utilized in biomedical research, particularly in lipid studies and drug delivery systems.
Tripalmitin serves as a representative model for studying triglycerides and their behavior in biological systems.

Microencapsulation:
Tripalmitin is employed in microencapsulation techniques to protect sensitive ingredients, such as flavors, fragrances, and pharmaceutical compounds.
Tripalmitin helps enhance stability, control release, and improve the shelf life of encapsulated substances.

Fuel Additive:
Tripalmitin can be used as a renewable fuel additive in biodiesel production.
Its chemical structure and properties make it suitable for blending with biodiesel fuels, improving their combustion characteristics.

Analytical Chemistry:
Tripalmitin is utilized in analytical chemistry as a calibration standard for various instrumental techniques, such as gas chromatography and mass spectrometry.
Tripalmitin helps validate and quantify analytical measurements.

Surfactant Systems:
Tripalmitin is sometimes employed as a surfactant or emulsifier in formulations.
Tripalmitin aids in the formation and stabilization of emulsions, foams, and dispersed systems.

Nanotechnology:
Tripalmitin is explored in nanotechnology applications, including nanoparticle synthesis and drug delivery systems.
Tripalmitin can be used as a matrix material or a component in nanoparticle formulations.

Bioplastics:
Tripalmitin is investigated as a potential ingredient in biodegradable and renewable bioplastics.
Its compatibility with other biopolymers offers possibilities for environmentally friendly packaging materials.

Veterinary Medicine:
Tripalmitin may have applications in veterinary medicine, such as in the formulation of animal pharmaceuticals, topical preparations, and nutritional supplements.


Tripalmitin is widely used as a texturizer, stabilizer, and emulsifier in processed foods, contributing to their texture and stability.
Tripalmitin is commonly found in baked goods, confectionery, margarine, and other food products.

Tripalmitin serves as an energy source in animal feed, providing essential calories for livestock and poultry.
In the cosmetics industry, tripalmitin acts as an emollient, enhancing the moisturizing properties of skincare products.
Tripalmitin is a key ingredient in lip balms, lipsticks, and moisturizing creams.
Tripalmitin is employed in the pharmaceutical field as a carrier for lipophilic drugs, aiding their absorption and bioavailability.

Tripalmitin is utilized in transdermal patches, solid oral dosage forms, and suppositories.
Tripalmitin is an essential component in industrial lubricants, improving the performance and durability of machinery.
Tripalmitin helps reduce friction, wear, and heat generation in moving parts.
Candle manufacturers use tripalmitin as a primary ingredient in wax formulations, enabling the production of high-quality candles with desirable burning characteristics.
Tripalmitin contributes to the hardness, structure, and fragrance retention of candles.

Tripalmitin finds application in the formulation of coatings and polishes, providing gloss, protection, and ease of application.
Tripalmitin is used in the production of wood polishes, leather conditioners, and metal protective coatings.
Tripalmitin is employed in the creation of industrial mold release agents, ensuring smooth and efficient mold release in manufacturing processes.
Tripalmitin acts as a plasticizer in certain materials, enhancing their flexibility and workability.

Tripalmitin is utilized in research and development as a model compound for studying lipid metabolism, drug delivery systems, and formulation development.
Tripalmitin is a valuable tool in lipid and bioactive compound studies.

Tripalmitin is employed in microencapsulation techniques to protect sensitive ingredients, such as flavors, fragrances, and pharmaceutical compounds.
Tripalmitin helps enhance stability, control release, and improve the shelf life of encapsulated substances.

Tripalmitin can serve as a renewable fuel additive in biodiesel production, improving the combustion properties of biodiesel fuels.
Tripalmitin aids in reducing emissions and enhancing the overall performance of biodiesel.
Analytical chemists utilize tripalmitin as a calibration standard in gas chromatography and mass spectrometry for accurate quantification of compounds.
Tripalmitin acts as a surfactant in formulations, aiding in the formation and stabilization of emulsions and foams.

Tripalmitin finds applications in nanotechnology, serving as a matrix material or component in nanoparticle formulations for drug delivery and other applications.
Veterinary medicine explores the use of tripalmitin in animal pharmaceuticals, topical preparations, and nutritional supplements.
Tripalmitin is used as a coating material in the production of confectionery items like chocolates and candy coatings, providing a smooth and glossy finish.

Tripalmitin acts as a binding agent in the manufacturing of tablets and pills, ensuring the cohesive integrity of the dosage forms.
Tripalmitin is employed in the production of nutritional supplements, particularly those containing fat-soluble vitamins and essential fatty acids.
Tripalmitin serves as a source of energy in energy bars and sports nutrition products.
Tripalmitin is utilized in the production of emulsified meat products such as sausages and processed meats, helping improve their texture and juiciness.

Tripalmitin is used in the formulation of dairy products like ice cream and whipped toppings to provide stability, smoothness, and enhanced mouthfeel.
Tripalmitin finds application in the production of bakery products like cookies and pastries, contributing to their texture, mouthfeel, and shelf life.
Tripalmitin is employed in the creation of cosmetic powders and pressed powders, enhancing their smoothness, adhesion, and blendability.

Tripalmitin is used as a film-forming agent in cosmetic and personal care products, providing a protective barrier on the skin or hair.
Tripalmitin finds application in the production of solid perfumes and fragrance sticks, ensuring the controlled release of fragrance over time.
Tripalmitin is utilized in the formulation of liposomal drug delivery systems, enabling the targeted and controlled release of therapeutic compounds.

Tripalmitin is explored in the field of tissue engineering and regenerative medicine as a scaffold material for cell growth and tissue regeneration.
Tripalmitin is employed in the creation of biodegradable packaging materials, reducing the environmental impact of plastic waste.
Tripalmitin is used as a lubricant in various industries, including automotive, manufacturing, and machinery, to reduce friction and wear.

Tripalmitin is employed in the production of adhesive tapes, providing adhesion and smooth unwinding properties.
Tripalmitin is used as a component in hair care products like conditioners and serums, providing nourishment, shine, and manageability.
Tripalmitin finds application in the formulation of sunscreens and sun protection products, aiding in the dispersion and stability of UV filters.

Tripalmitin is utilized in the creation of pet care products like shampoos and conditioners, offering moisturizing and nourishing benefits to animal fur and skin.
Tripalmitin is explored in the field of drug delivery systems for targeted and sustained release of therapeutic compounds in cancer treatment.
Tripalmitin finds application in the creation of bio-based lubricants and greases, providing effective lubrication while reducing environmental impact.
Tripalmitin is used in the production of nutritional infant formulas, contributing to the energy content and nutritional profile of the product.

Tripalmitin is employed in the creation of high-performance coatings for applications in aerospace, marine, and industrial sectors, providing protection against corrosion and wear.
Tripalmitin finds application in the formulation of solid-state phase change materials, used for thermal energy storage and management in various industries.
Tripalmitin is utilized in the production of dietary supplements for weight management, as it provides a source of long-lasting energy.
Tripalmitin is explored in the field of gene delivery systems, offering a potential carrier for the delivery of genetic material in gene therapy applications.



DESCRIPTION


Tripalmitin, also known as glycerin tripalmitate, is a chemical compound classified as a triglyceride.
Tripalmitin is formed by the esterification of glycerol (also called glycerin) with three molecules of palmitic acid.
Its chemical formula is C₅₃H₁₀₀O₆, and its molecular weight is approximately 853.43 g/mol.

Tripalmitin is a solid substance that appears as a white or off-white powder or crystalline material.
Tripalmitin is odorless and insoluble in water.
However, Tripalmitin is soluble in organic solvents such as ethanol, chloroform, and ether.

This triglyceride is naturally found in various fats and oils, including palm oil and animal fats.
Tripalmitin serves as an energy storage molecule in organisms and is a major component of dietary fats.
Tripalmitin is commonly used in the food industry as a fat source, emulsifier, and stabilizer.
Tripalmitin is also employed in the formulation of cosmetics, pharmaceuticals, and personal care products due to its desirable properties as an emollient and thickening agent.

Tripalmitin is a triglyceride composed of three palmitic acid molecules esterified to a glycerol backbone.
Tripalmitin is a white, waxy solid with a powdery texture.
Tripalmitin is odorless and tasteless.
Tripalmitin has a melting point around 63-65 degrees Celsius.

The compound is insoluble in water but soluble in organic solvents.
Tripalmitin is derived from natural sources such as palm oil and animal fats.

Tripalmitin is commonly found in dietary fats and oils.
Tripalmitin serves as an energy reservoir in living organisms.
Tripalmitin is a major constituent of many food products.

Tripalmitin acts as a natural emollient, providing moisturizing properties to skincare products.
Tripalmitin has a long shelf life and is resistant to oxidation.
Tripalmitin is stable under normal storage and handling conditions.
Tripalmitin has low volatility, making it suitable for various formulations.

Tripalmitin is used as a thickening agent in cosmetics and personal care products.
Tripalmitin helps improve the texture and consistency of formulations.
Tripalmitin is widely utilized in the pharmaceutical industry for drug delivery systems.
Tripalmitin can serve as a carrier for lipophilic drugs.

Tripalmitin has good compatibility with many active ingredients.
Tripalmitin exhibits excellent stability in different formulations and environments.
Tripalmitin is biodegradable and poses minimal environmental impact.
Tripalmitin is an FDA-approved ingredient for various food applications.
Tripalmitin contributes to the smoothness and mouthfeel of food products.



PROPERTIES


Physical Properties:

Molecular Formula: C51H98O6
Molecular Weight: 807.36 g/mol
Appearance: White to off-white solid
Odor: Odorless
Melting Point: Approximately 63-65°C (145-149°F)
Boiling Point: Decomposes before boiling
Solubility: Insoluble in water, soluble in organic solvents (e.g., ethanol, acetone)

Chemical Properties:

Chemical Formula: C3H5(C16H31O2)3
Chemical Structure: Tripalmitin is a triglyceride consisting of glycerol linked to three palmitic acid molecules.
Lipid Type: Saturated triglyceride
Hydrophobicity: Tripalmitin is hydrophobic (water-insoluble) due to its long hydrocarbon chains.



FIRST AID


Inhalation:

If tripalmitin particles or dust are inhaled, remove the affected person to a well-ventilated area.
If respiratory symptoms develop, such as coughing or difficulty breathing, seek medical attention immediately.
Provide supportive care, such as fresh air, rest, and reassurance.


Skin Contact:

In case of contact with tripalmitin on the skin, immediately remove contaminated clothing.
Gently wipe or blot away any excess tripalmitin from the skin surface.
Wash the affected area thoroughly with mild soap and water.
If skin irritation, redness, or rash occurs and persists, seek medical advice.
Apply a suitable skin moisturizer or emollient to help alleviate dryness or discomfort.


Eye Contact:

In the event of contact with tripalmitin in the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes, ensuring thorough rinsing of the eye surfaces.
If wearing contact lenses, remove them during the rinsing process.
Seek immediate medical attention and bring the Safety Data Sheet (SDS) or product container for reference.


Ingestion:

If tripalmitin is accidentally ingested, do not induce vomiting unless directed to do so by medical professionals.
Rinse the mouth with water to remove any residual product.
Do not give anything by mouth to an unconscious or convulsing person.
Seek immediate medical attention, and provide the healthcare professional with relevant information, including the quantity and time of ingestion.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling tripalmitin, wear appropriate PPE, including gloves, safety goggles, and protective clothing, to minimize the risk of skin contact and eye irritation.

Ventilation:
Ensure proper ventilation in the working area to prevent the buildup of airborne particles or vapors.

Avoid Heat Sources: Keep tripalmitin away from open flames, sparks, and direct heat sources, as it may melt or ignite at high temperatures.

Prevent Contamination:
Take precautions to prevent cross-contamination with incompatible substances, such as strong oxidizing agents or reactive chemicals.

Good Hygiene Practices:
Wash hands thoroughly with soap and water after handling tripalmitin, especially before eating, drinking, or smoking.


Storage:

Store in a Cool, Dry Place:
Keep tripalmitin containers tightly closed in a cool, dry, and well-ventilated area to prevent moisture absorption and degradation.

Temperature Control:
Maintain storage temperatures below the melting point of tripalmitin (approximately 63-65°C or 145-149°F) to ensure its solid-state and prevent product degradation.

Protect from Light:
Store tripalmitin in opaque containers or areas protected from direct sunlight or strong UV radiation, as exposure to light may lead to color changes or degradation.

Segregation:
Store tripalmitin away from strong oxidizing agents, acids, and reactive substances to prevent potential chemical reactions.

Keep Away from Ignition Sources:
Store tripalmitin away from ignition sources, such as open flames, sparks, or heat-producing equipment, to minimize the risk of fire hazards.

Proper Labeling:
Clearly label containers with the product name, batch number, date of receipt, and any relevant hazard information.



SYNONYMS


Glycerol tripalmitate
Glycerin tripalmitate
Glyceryl tripalmitate
Palmitin triglyceride
Glyceryl palmitate triester
Tripalmitin glyceride
Triglyceride of palmitic acid
Palmitic acid triglyceride
Palm oil glyceride
Glyceryl ester of palmitic acid
Glycerol ester of palmitic acid
Glyceryl palmitate
Palmitin
Palmitic triglyceride
Glycerol palmitate
Palmitoyl glycerol
Palmitic acid ester of glycerol
Tripalmitin ester
Glyceryl palmitin
Palmitate ester of glycerol
Glyceride of palmitic acid
Trihexadecanoin
1,2,3-Trihexadecanoylglycerol
1-Palmitoyl-2,3-dipalmitin
Hexadecanoic acid ester with glycerol
Tripalmitoylglycerol
Glycerol palmitate ester
Glyceryl palmitate triglyceride
Palmitic acid glycerol ester
1,2,3-Propanetriyl palmitate
Glycerol tris(hexadecanoate)
Triglycerol palmitate
1,3-Dihydroxypropan-2-yl hexadecanoate
Palmitic acid glyceride
Hexadecanoyl glycerol
Glycerol trihexadecanoate
Tris(hexadecanoyloxy)methyl propane
Glycerin tris(palmitate)
Tri(hexadecanoyl)glycerol
Glycerol trihexadecanoate
Tris(palmitoyloxy)methyl propane
1,3-Bis(hexadecanoyloxy)propan-2-yl palmitate
Glycerol 1,2,3-tripalmitate
Palmitic acid glyceryl ester
1,2,3-Tri(hexadecanoyloxy)propane
Tris(hexadecanoyloxy)methylpropane
Glycerin tris(palmitin)
Trihexadecyl glycerol
1,2,3-Tri(hexadecanoyloxy)propane
Hexadecyl 1,2,3-tripalmitate
Triglycerol palmitate
Glyceryl palmitate tripalmitate
Trihexadecanoyl glycerol
Glycerol trihexadecanoate
Hexadecyl palmitate
Glycerol tris(hexadecanoic acid ester)
Glycerol tripalmitate ester
1,2,3-Propanetriyl palmitate
Tris(hexadecanoyl)glycerol
Trihexadecylglycerol
Hexadecanoate ester of glycerol
1,2,3-Trihexadecanoylglycerol
Glycerin trihexadecanoate
Glycerol tris(palmitic acid ester)
Trihexadecyl glyceryl ester
Hexadecanoate glycerol ester
Glycerol 1,2,3-trihexadecanoate
Tris(palmitoyloxy)methylpropane
1,3-Dihydroxypropan-2-yl palmitate
1,3-Bis(hexadecanoyloxy)propan-2-yl palmitate
Hexadecyl 1,2,3-trihexadecanoate
Glycerin tris(palmitoyl ester)
1,2,3-Tri(hexadecanoyloxy)propane
Trihexadecanoyl glyceryl ester
Glycerol trihexadecanoylate

TRIPHENYL PHOSPHATE, N° CAS : 115-86-6, Nom INCI : TRIPHENYL PHOSPHATE, Nom chimique : Phosphoric acid, triphenyl ester, N° EINECS/ELINCS : 204-112-2, Ses fonctions (INCI) Agent plastifiant : Adoucit et rend souple une autre substance qui autrement ne pourrait pas être facilement déformée, dispersée ou être travaillée

T 309; tris(phe;NSC 57867; TRIPHENYLTHIOPHOSPHATE; T 309 (antiwear additive); Triphenyl Phosphorothioate; O,O,O-Triphenylthiophosphat; Triphenoxyphosphine sulfide; TRIPHENYL PHOSPHOROTHIONATE; O,O,O-Triphenyl thiophosphate CAS NO:597-82-0

Triphenyl phosphate (TPP) is colorless, crystalline powder with a phenol-like odor.
Triphenyl phosphate (TPP) has a role as a flame retardant and a plasticiser.


CAS Number: 115-86-6
EC Number: 204-112-2
MDL number: MFCD00003031
Linear Formula: (C6H5O)3PO
Chemical formula: C18H15O4P



SYNONYMS:
triphenylphosphate, phosphoric acid, triphenyl ester, disflamoll tp, triphenoxyphosphine oxide, celluflex tpp, phosflex tpp, trifenylfosfat, phenyl phosphate pho 3po, phosphoric acid triphenyl ester, trifenylfosfat czech, TPP, TPPA, Tripheyl phosphate, TRIPHENYL PHOSPHATE (TPP), PHOSPHORIC ACID TRIPHENYL ESTER, Phosflex TPP, Triphenyl hosphate, Altal, Dymel, Wako TPP, Phosphoric acid,triphenyl ester, Celluflex TPP, Triphenyl phosphate, Phenyl phosphate ((PhO)3PO), Triphenoxyphosphine oxide, Disflamoll TP, TP, Phosflex TPP, TPP, TPPA, Reofos TPP, S 4, S 4 (phosphate), TTP, Sumilizer TPP, Wako TPP, NSC 57868, Phoscon FR 903N, TFF, WSFR-TPP, Triphenol phosphate, TTP (triphenyl phosphate), DHPF 005, Antioxidant TTP, UN 3077, Disflamoll TPP, FR 3031, 402955-02-6, Triphenyl phosphate, TPP, Phosphoric acid, triphenyl ester, Celluflex TPP, Disflamoll TP, Phenyl phosphate ((PhO)3PO), Phosflex TPP, Triphenoxyphosphine oxide, TP, Trifenylfosfat, Altal, Dymel, Kronitex TPP, Phenyl phosphate, Triphenyl phosphoric acid ester, NSC 57868, TPhP, Triphénylphosphate, Trifenilfosfato, TPP, Phosphoric acid, triphenyl ester, Celluflex TPP, Disflamoll TP, Phenyl phosphate ((PhO)3PO), Phosflex TPP, Triphenoxyphosphine oxide, TP, Trifenylfosfat, Altal, Kronitex TPP, Phenyl phosphate, Triphenyl phosphoric acid ester, NSC 57868, phenyl phosphate, TPP, triphenyl ester of phosphoric acid, Celluflex TPP, Disflamoll TP, Phenyl phosphate ((PhO)3PO), Phosflex TPP, Phosphoric acid, triphenyl ester, TP (VAN), TPP, Trifenylfosfat [Czech], Triphenoxyphosphine oxide, Triphenyl phosphate, Triphenylphosphate, [ChemIDplus], phenyl phosphate, TPP, Phosphoric acid triphenyl ester, triphenyl phosphoric acid ester, celluflex tpp, TRIPHENYL PHOSPHATE, 115-86-6, Triphenylphosphate, Phosphoric acid, triphenyl ester, Disflamoll TP, Celluflex TPP, Phosflex TPP, Triphenoxyphosphine oxide, Trifenylfosfat, Phenyl phosphate ((PhO)3PO), Phosphoric Acid Triphenyl Ester, NSC 57868, TPPA, CCRIS 4888, HSDB 2536, UNII-YZE19Z66EA, EINECS 204-112-2, YZE19Z66EA, BRN 1888236, DTXSID1021952, CHEBI:35033, AI3-04491, NSC-57868, Triphenyl phosphoric acid ester, DTXCID201952, EC 204-112-2, 4-06-00-00720 (Beilstein Handbook Reference), Triphenyl Phosphate 1000 microg/mL in Acetone, Triphenyl phosphate 10 microg/mL in Ethyl acetate, Trifenylfosfat [Czech], Triphenyl phosphate 500 microg/ml in Methyl-tert-butyl ether, Reofos TPP, CAS-115-86-6, TPHP, C18H15O4P, Triphenyl Phosphate (TPP), Altal, Kronitex TPP, Reolube TPP, Reomol TPP, TPP; TPHP, NCIOpen2_007435, Triphenyl Phosphate, Reagent, SCHEMBL18116, Phenyl phosphate, (PhO)3PO, BIDD, , Triphenyl phosphate, >=99%, CHEMBL454511, TRIPHENYL PHOSPHATE [MI], WLN: ROPO & OR & OR, Triphenyl phosphate (TPP, TPhP), TRIPHENYL PHOSPHATE [HSDB], NSC57868, Tox21_201511, Tox21_300504, MFCD00003031, STL280499, AKOS015888630, Triphenyl phosphate, analytical standard, NCGC00164033-01, NCGC00164033-02, NCGC00164033-03, NCGC00254408-01, NCGC00260671-01, AC-19461, CS-0017793, NS00010271, P0272, A803498, Q418573, J-003328, Triphenyl phosphate, TraceCERT(R), 31P-qNMR Standard, Triphenyl phosphate (TPP) 500 microg/mL in Methyl tert-butyl ether



Triphenyl phosphate (TPP) is a solid phosphate ester which imparts good flame retardance to a large number of polymers.
Triphenyl phosphate (TPP) is a clear liquid, used as a performance additive to improve the colour and clarity of alkyd resin, unsaturated polyester resin and various industrial oils during their manufacture.


The manufacture of various resins involves the use of high temperatures, usually in excess of 150° C.
At these temperature the reaction mass tends to get coloured due to oxidation.
Triphenyl phosphate (TPP), n°115-86-6 is determined by GC-MS. Sample material must be taken using special equipment.


Triphenyl phosphate (TPP) is found in the photography industry. It is also a fire retardant.
Triphenyl phosphate (TPP) is a solid phosphate ester which imparts good flame retardance to a large number of polymers.
Triphenyl phosphate (TPP) is an aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol.


Triphenyl phosphate (TPP) has a role as a flame retardant and a plasticiser.
Triphenyl phosphate (TPP) is functionally related to a phenol.
Triphenyl phosphate (TPP) is a colorless, crystalline solid widely and safely used by many industries around the world.


Triphenyl phosphate (TPP) provides many benefits to consumer products – from preventing electrical and automobile fires to increasing flexibility and durability of such products as photographic films.
Triphenyl phosphate (TPP) is colorless, crystalline powder with a phenol-like odor.


Triphenyl phosphate (TPP) is one of many chemical compounds that are part of multicomponent substances based on phosphorus esters.
Due to the adverse effects of this chemical compound on the environment, low Triphenyl phosphate (TPP) solutions are required in some applications.
Following the requirements of the market and in the interests of human health and environmental health, the PCC Group has developed a technology to obtain phosphorus esters with low levels of Triphenyl phosphate (TPP).


This group of chemicals includes products bearing the sign “Low TPP”.
Triphenyl phosphate (TPP) available as white flake or crystal.
Triphenyl phosphate (TPP) acts as a flame retardant, non-flammable plasticizer or additive in cellulose for photographic film, polyester and polyurethane.


Triphenyl phosphate (TPP) exhibits insolubility in water and solubility in benzene, chloroform, ether and acetone.
Triphenyl phosphate (TPP) is a colorless solid.
The primary uses for Triphenyl phosphate (TPP) are as a flame retardant or solvent in chemical and plastics manufacturing.


Information from the 2016 Chemical Data Reporting (CDR) for Triphenyl phosphate (TPP) indicates the reported production volume is between 1 million and 10 million lbs/year (manufacture and import).
Triphenyl phosphate (TPP), in the form of a white, odorless crystalline powder, is a flame-retardant plasticizer.


Its crystallization point begins above 47 degrees Celsius, and Triphenyl phosphate (TPP) contains less than .1 mg of potassium hydroxide per gram.
Triphenyl phosphate (TPP) is a non-halogen flame retardant plasticizer.
Triphenyl phosphate (TPP) is present as a white flaky crystal.


Compatible with phenolic resins, cellulose resin, vinyl resin and rubber, and some engineering plastics such as PPO.
Triphenyl phosphate (TPP) is the chemical compound with the formula OP(OC6H5)3.
Triphenyl phosphate (TPP) is the simplest aromatic organophosphate.


This colourless solid, Triphenyl phosphate (TPP), is the ester (triester) of phosphoric acid and phenol.
Nail polish has received particular interest as a source of exposure to Triphenyl phosphate (TPP).
Triphenyl phosphate (TPP) appears as colorless crystals.


Triphenyl phosphate (TPP) is an aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol.
Triphenyl phosphate (TPP) has a role as a flame retardant and a plasticiser.
Triphenyl phosphate (TPP) is functionally related to a phenol.


Triphenyl phosphate (TPP) is an organophosphate flame retardant.
Triphenyl phosphate (TPP) is part of the group of Non-Halogenated Aromatic Phosphates.
Triphenyl phosphate (TPP) is part of the group of Organophosphate Flame Retardants (OPFRs).


Triphenyl phosphate (TPP) is a chemical compound in the form of a colourless solid.
Triphenyl phosphate (TPP) is the ester (triester) of phosphoric acid and phenol.
Triphenyl phosphate (TPP) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 tonnes per annum.



USES and APPLICATIONS of TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) can be used as flame retardant plasticizer for cellulose resin, vinyl resin, natural rubber and synthetic rubber, with low flame retardant efficiency, excellent mechanical retention, transparency, softness and strong toughness.
Triphenyl phosphate (TPP) is used in nitrocellulose, various coatings, rigid polyurethane foam plastics, engineering plastics plasticizers, and flame retardant additives.


Triphenyl phosphate (TPP) is mainly used as a flame retardant plasticizer for engineering plastics and phenolic resin laminates;
Triphenyl phosphate (TPP) is used as softener of synthetic rubber and raw material of trimethyl phosphate;
Triphenyl phosphate (TPP) is used as a plasticizer, fire-retardant, and substitute for camphor in celluloid; also used in lubricating oils and hydraulic fluids.


Triphenyl phosphate (TPP) acts as an anti-oxidant and prevents colour formation of the finished product, as a result of which better quality resins are obtained.
Triphenyl phosphate (TPP) is used paint, Coating, Ink


Triphenyl phosphate (TPP) is used as stabilizer
Triphenyl phosphate (TPP) is used polymers (including) Adhesives, Styrenics, Engineering, Thermoplastics, Polymers.
Triphenyl phosphate (TPP) is used to regulate Viscosity and improve colour stability


Polyolefins: Triphenyl phosphate (TPP) is used as catalyst
Polyurethane hot melt adhesives, SBR Rubber, Epoxies
Triphenyl phosphate (TPP) is used to prevent scorching during curing and improve colour stability


Triphenyl phosphate (TPP) is a commonly used flame retardant and plasticizer in various industries.
Triphenyl phosphate (TPP) is used for this analysis, the lab adopts the following method: Inhouse.
Triphenyl phosphate (TPP) is used Flame Retardants, Plastic, Resin & Rubber, Plasticizers


Triphenyl phosphate (TPP) is used as flame retardant and processing aid in cellulose acetate, cellulose acetate butyrate and vinyl copolymer compounds which are used in moulding applications.
Other important applications of Triphenyl phosphate (TPP) are coatings based on nitrocellulose, phenolic resins, ABS/PC and HIPS/PPE compounds.


Studies support the safe use of Triphenyl phosphate (TPP) in its different applications.
Triphenyl phosphate (TPP) is used in some nail polish and nail enamels, basecoats and undercoats, and manicuring products.
Triphenyl phosphate (TPP) is used in very low concentrations, primarily to increase the flexibility and durability of nail polish products, and improve adhesion of the product to the nail plate.


Triphenyl phosphate (TPP) is known as a product with manifold fields of applications regarding its qualities in particular as a flame retardant.
One primary use of Triphenyl phosphate (TPP) is as a flame retardant in phenolic- and phenylene oxide-based resins for the manufacture of electrical and automobile components, for auto upholstery, and as a nonflammable plasticizer in cellulose acetate for photographic films.


Triphenyl phosphate (TPP) has also been used to impregnate roofing paper.
Triphenyl phosphate (TPP) occurs as a plasticizer in various lacquers and varnishes, and as a component of lubricating oil and hydraulic fluids.
Triphenyl phosphate (TPP) is used in the insecticidal composition.


Triphenyl phosphate (TPP) is also used in hydraulic liquids, and adhesives, inks, coatings, as a plasticizer in lacquers and varnishes, and as a substitute for camphor in celluloid materials to make the latter stable and fireproof.
Triphenyl phosphate (TPP) can be used in coatings, nitrocellulose applications, and rigid polyurethane foams.


Triphenyl phosphate (TPP) is used in many plastics and resins (such as phenolic resin, cellulose resin, epoxy resin, PVC, PP, PC, ABS and PC/ABS).
Triphenyl phosphate (TPP) is used as an internal standard in the screening and quantification of agrochemical residues in vegetables and fruits.
Triphenyl phosphate (TPP) is used in plastic processing and molding of plastic flow and performance.


Triphenyl phosphate (TPP) is used as an internal standard in the screening and quantification of agrochemical residues in vegetables and fruits.
Triphenyl phosphate (TPP) is used in plastic processing and molding of plastic flow and performance.
Triphenyl phosphate (TPP) is used as a plasticiser in a wide variety of fields and objects.


Triphenyl phosphate (TPP) is also used as a flame retardant for certain materials including electronic equipment, PVC, hydraulic fluids, glues, nail polishes and moulding resins.
To be effective as a flame retardant, Triphenyl phosphate (TPP) acts as follows: phosphoric acid is formed during thermal decomposition.


This reacts to form pyrophosphoric acid.
In Triphenyl phosphate (TPP)'s condensed phase, pyrophosphoric acid acts to block heat transfer.
Triphenyl phosphate (TPP) is active in the gas phase.


The gradual phase-out of PBDEs may explain the increased use of triphenyl phosphate.
Triphenyl phosphate (TPP) has been added as a flame retardant to a variety of products, such as foam used in upholstered furniture, children’s products, and electronic equipment.


Triphenyl phosphate (TPP) is also used in some nail polish and as an additive to increase the durability and flexibility of some plastics.
Triphenyl phosphate (TPP) is also used as a plasticizer in lacquers, varnishes, and hydraulic fluids.
Triphenyl phosphate (TPP) has been used widely as a flame retardant and plasticizer.


Triphenyl phosphate (TPP) has been used as a flame retardant for a variety of materials, including electronic equipment, PVC, hydraulic fluids, glues, in nail polishes, and casting resins.
Triphenyl phosphate (TPP)'s mechanism of action as a flame retardant is as follows: first, during thermal decomposition, phosphoric acid is formed.



This reacts to form pyrophosphoric acid, which, when in Triphenyl phosphate (TPP)'s condensed phase, acts to block heat transfer.
One of the most effective flame retardants for certain polymers, Triphenyl phosphate (TPP) is only active as an additive flame retardant in its gas phase.
Phase out of PBDEs may have increased the use of Triphenyl phosphate (TPP) in recent years.


Triphenyl phosphate (TPP) is used as a plasticizer and a fire retardant in a wide variety of settings and products.
Triphenyl phosphate (TPP) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Triphenyl phosphate (TPP) is used in the following products: adhesives and sealants, coating products and cosmetics and personal care products.
Other release to the environment of Triphenyl phosphate (TPP) is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).


Release to the environment of Triphenyl phosphate (TPP) can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).


Other release to the environment of Triphenyl phosphate (TPP) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Triphenyl phosphate (TPP) can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).


Triphenyl phosphate (TPP) can be found in products with material based on: fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper) and plastic (e.g. food packaging and storage, toys, mobile phones).


Triphenyl phosphate (TPP) is used in the following products: adhesives and sealants, coating products and laboratory chemicals.
Triphenyl phosphate (TPP) is used in the following areas: scientific research and development.


Other release to the environment of Triphenyl phosphate (TPP) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).


Triphenyl phosphate (TPP) is used in the following products: polymers and cosmetics and personal care products.
Release to the environment of Triphenyl phosphate (TPP) can occur from industrial use: formulation in materials and formulation of mixtures.
Triphenyl phosphate (TPP) is used in the following products: polymers.


Triphenyl phosphate (TPP) is used in the following areas: scientific research and development.
Triphenyl phosphate (TPP) is used for the manufacture of: plastic products, textile, leather or fur, electrical, electronic and optical equipment and machinery and vehicles.


Release to the environment of Triphenyl phosphate (TPP) can occur from industrial use: in the production of articles.
Release to the environment of Triphenyl phosphate (TPP) can occur from industrial use: manufacturing of the substance.



CONDITIONS OF USE OF TRIPHENYL PHOSPHATE (TPP):
In the final scope, EPA identified conditions of use associated with the importing; processing; distribution in commerce; industrial, commercial and consumer uses; and disposal of Triphenyl phosphate (TPP), for example:

*The flame retardant is processed as a reactant, incorporated into a formulation, mixture, or reaction products, and incorporated into articles;
*Triphenyl phosphate (TPP) is reportedly used in commercial paints and coatings and for plastic and rubber products; and
*Several consumer uses were reported, including foam seating and bedding products.
*The above listed conditions of use are ways that a person or the environment could be potentially exposed to this chemical.



PREPARTION OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) is prepared by reacting phosphorus pentoxide and phenol, or by reacting phosphorus oxychloride and phenol.
On a larger scale phosphorus oxychloride and phenol are reacted in an esterification tank with heating.
The HCL formed is trapped and condensed, while the crude Triphenyl phosphate (TPP) runs into a large tank where it is purified.



REACTIVITY PROFILE OF TRIPHENYL PHOSPHATE (TPP):
Organophosphates, such as Triphenyl phosphate (TPP), are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.
Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.



PREPARTION OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) is prepared by the SN2 reaction of phosphorus oxychloride and phenol.



CHEMICAL PROPERTIES OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) is a colorless crystalline powder with a faint, phenol-like odor.
Triphenyl phosphate (TPP) is practically insoluble in water at 1.9 × 10 7 mg/l at 24 °C.

Triphenyl phosphate (TPP) is very soluble in carbon tetrachloride and is soluble in most lacquers, solvents, thinners, and oils, as well as in alcohol, benzene, ether, chloroform, and acetone.

Triphenyl phosphate (TPP) begins to decompose at about 600 °C in inert gas, and in a large excess of air, complete combustion to carbon dioxide occurs in the range 800–900 °C.
Hydrolysis of Triphenyl phosphate (TPP) occurs very slowly in acidic or neutral solutions, but occurs rapidly in alkaline solutions.



CHEMICAL/PHYSICAL PROPERTIES OF TRIPHENYL PHOSPHATE (TPP):
When an aqueous solution containing Triphenyl phosphate (TPP) (0.1 mg/L) and chlorine (3 to 1,000 mg/L) was stirred in the dark at 20 °C for 24 h, the benzene ring was substituted with one to three chlorine atoms.
The reported hydrolysis half-lives at pH values of 8.2 and 9.5 were 7.5 and 1.3 d, respectively.
Triphenyl phosphate (TPP) decomposes at temperatures greater than 410 °C



SOLUBILITY OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) reacts with water.



NOTES OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) is incompatible with oxidizing agents and moisture.
Store Triphenyl phosphate (TPP) under dry inert gas.
Protect Triphenyl phosphate (TPP) from humidity and water.



FEATURES OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP)is useful for plastic, which is of cellulose ester radical, and it is insoluble in gas, nonflammable and it has good light stability.

Plastic uses of Triphenyl phosphate (TPP): Acrylonitrile, butadienestyrene copolymer, acetate fibre, cellulose nitrate, polyester, polyvinyl chloride, polyvinyl acetate, polyolepine, polyaminoester (PU soft).

Triphenyl phosphate (TPP) noncombustable substitute for camphor in celluloid.
Triphenyl phosphate (TPP) is used plasticizer in plastics (e.g., cellulose acetate) lacquers, varnishes, etc.
Triphenyl phosphate (TPP) is also used in impregnating roofing paper.



TRANSPORTATION PRECAUTIONS OF TRIPHENYL PHOSPHATE (TPP):
1. The package of Triphenyl phosphate (TPP) shall be complete and the loading shall be safe.
During transportation, ensure that containers do not leak, collapse, fall or damage.

Triphenyl phosphate (TPP) is strictly prohibited to mix with oxidant and transport.
During transportation, Triphenyl phosphate (TPP) shall be protected from sun exposure, rain and high temperature;


2. Storage precautions:
store Triphenyl phosphate (TPP) in a cool and ventilated warehouse.
Keep away from fire and heat.

Triphenyl phosphate (TPP) should be stored separately from the oxidant, avoiding mixed storage.
Fire fighting equipment of corresponding variety and quantity shall be provided.
The storage area shall be equipped with appropriate materials to contain the leakage.



SOLUBILITY OF TRIPHENYL PHOSPHATE (TPP):
Triphenyl phosphate (TPP) is insoluble in water, easily hydrolyzed to free phenol in case of moisture, soluble in organic solvents such as alcohol, ether, benzene and acetone, which has absorption effect on ultraviolet rays.



PHYSICAL and CHEMICAL PROPERTIES of TRIPHENYL PHOSPHATE (TPP):
Chemical Formula: C₁₈H₁₅O₄P
Molar Mass: 326.288 g·mol⁻¹
Molecular Weight: 326.3 g/mol
Exact Mass: 326.07079595 g/mol
Monoisotopic Mass: 326.07079595 g/mol
Physical Properties
Appearance: Colorless solid
Density: 1.184 g/mL
Melting Point: 48 to 50 °C (118 to 122 °F; 321 to 323 K)
Boiling Point: 244 °C (471 °F; 517 K) at 10 mmHg
Vapor Pressure: 1 mmHg at 193 °C
Chemical Characteristics
XLogP3: 4.6

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 6
Topological Polar Surface Area: 44.8 Ų
Heavy Atom Count: 23
Formal Charge: 0
Complexity: 325
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

CAS Number: 115-86-6
EC Number: 204-112-2
Hill Formula: C₁₈H₁₅O₄P
Chemical Formula: (C₆H₅O)₃PO
Molar Mass: 326.29 g/mol
HS Code: 2919 90 30
Physical Properties
Physical State: Flakes
Color: White
Odor: No data available
Melting Point/Freezing Point: 48 - 50 °C (lit.)
Boiling Point: 220 °C (5 hPa)
Density: 1.2 g/cm³ (50 °C)
Relative Density: 1.21 at 50 °C

Bulk Density: 650 kg/m³
Flash Point: 220 °C (closed cup)
Ignition Temperature: >500 °C
Decomposition Temperature: No data available
pH: No data available
Viscosity: No data available (kinematic and dynamic)
Water Solubility: 0.0019 g/L at 20 °C (slightly soluble)
Vapor Pressure: 1.73 hPa at 200 °C; 0.1 hPa at 150 °C
Relative Vapor Density: No data available
Partition Coefficient (n-octanol/water): log Pow: 4.63 at 20 °C (Potential bioaccumulation)
Additional Properties
Refractive Index: 1.563 at 50 °C

Specific Gravity: 1.185-1.202
Acid Value: ≤0.1 mg KOH/g
Free Phenol: ≤50 mg/kg
Water Content: ≤0.1%
Color (APHA): ≤80
Phosphorus Content: 9.5% (calculated)
Hazen Color Value: ≤50 (in melt)
Log Pow: 4.6 at 20 °C
Safety and Stability
Flammability: Combustible Solid
Explosive Properties: No data available
Oxidizing Properties: None
Storage Conditions: Store below +30°C

Autoignition Temperature: No data available
Decomposition Temperature: No data available
General Information
Chemical Name: Phosphoric acid triphenyl ester; Triphenyl Phosphate (TPP)
CAS Number: 115-86-6
EINECS Number: 204-112-2
Molecular Formula: C₁₈H₁₅O₄P
Molecular Weight: 326.29 g/mol
Physical Properties
Appearance: White flakes or pellets; colorless crystal powder or needles
Color (APHA): ≤ 80
Odor: Odorless

Density: 1.205 g/cm³ at 50 °C; 1.185-1.202 (specific gravity)
Refractive Index: 1.555 at 50 °C; 1.550
Melting Point: 48-50 °C
Freezing Point: 48-50 °C
Boiling Point: 245 °C at 11 mmHg
Flash Point: 220 °C (428 °F) - closed cup
Viscosity at 50 °C: 11 mPa·s
Chemical Characteristics
Acid Value: ≤ 0.1 mg KOH/g; ≤ 0.05 mg KOH/g (specific grades)
Free Phenol: ≤ 50 mg/kg; 0.03 MAX
Water Content: ≤ 0.1%
Phosphorus Content: 9.5% (calculated)

Solubility and Stability
Solubility: Insoluble in water
Storage Conditions: 2-8 °C
Hazen Color Value: ≤ 50 (in melt)
Additional Information
Content: ≥ 99.0%
Flash Point (cc): 220 °C
Molecular Weight: 326.28-326.29 g/mol
Chemical Formula: C₁₈H₁₅O₄P
Molecular Weight: 326.28300 g/mol
Exact Mass: 326.28 g/mol

CAS Number: 115-86-6
EC Number: 204-112-2
HS Code: 2919 90 30
Hill Formula: C₁₈H₁₅O₄P
Physical Properties:
Appearance: Colorless crystals or flakes
Color: White (Colorless to faint yellow in some formulations)
Odor: Odorless
Density: 1.2055 g/cm³ at 50 °C
Specific Gravity: 1.268 at 50 °C; 1.180-1.186 at 25 °C
Melting Point: 49-50 °C
Boiling Point: 245 °C at 11 mmHg (lit.)
Flash Point: 220 °C (428 °F) - closed cup

Refractive Index: 1.563 (at 50 °C), 1.580-1.589 (at 25 °C)
Water Solubility: Insoluble (0.0019 g/L at 20 °C)
Vapor Pressure: 1.3 mm Hg at 200 °C
Vapor Density: 1.19 (Air = 1)
Flammability: Combustible Solid
Chemical Characteristics:
Partition Coefficient (log Pow): 4.6
Topological Polar Surface Area (PSA): 54.57 Ų
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 6
Safety and Storage:

Storage Conditions: 2-8 °C
Autoignition Temperature: >500 °C
Stability: Stable
Decomposition Temperature: No data available
Solubility:
Solvents: Benzene, chloroform, ether, acetone, lacquers, solvents, thinners, oil
Additional Information:
Phosphorus Content: 9.8-10.1%
Acidic Value: ≤ 0.5 mg KOH/g
Freezing Point: 22-24 °C
Chemical Name: Phosphoric acid triphenyl ester; Triphenyl Phosphate (TPP)
Chemical Name: Triphenyl phosphate

CAS Number: 115-86-6
EC Number: 204-112-2
Hill Formula: C₁₈H₁₅O₄P
Chemical Formula: (C₆H₅O)₃PO
Molecular Weight: 326.3 g/mol
Formula Weight: 326.29 g/mol
HS Code: 2919 90 30
Physical Properties
Appearance: Colorless, crystalline powder with a phenol-like odor
Color: White
Physical State: Flakes
Odor: Odorless

Melting Point/Freezing Point: 48 - 52 °C (118 - 124 °F)
Boiling Point: 244 - 250 °C (473 °F at 11 mmHg)
Density: 1.2055 g/cm³ (1.184 g/mL at 50 °C)
Specific Gravity: 1.185 - 1.202
Flash Point: 220 - 435 °F (220 °C to 433 °F)
Vapor Pressure: 1 - 1.73 hPa (1 mmHg at 193-200 °C)
Refractive Index: 1.550 - 1.563
Vapor Density: 11.3 (vs air)
Viscosity: 11 mm²/s at 50 °C
Henry's Law Constant: 5.88 at 20 °C (approximate)
Water Solubility: 0.0019 g/L at 20 °C (insoluble)
Storage Temperature: Store below +30°C

Chemical Properties
XLogP3: 4.6
Topological Polar Surface Area (PSA): 44.8 Ų
Log Pow: 4.6 at 20 °C
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 6
Complexity: 325
Defined/Undefined Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Safety and Regulations
UN Number: UN3077
Beilstein Reference: 1888236
Merck Index: 14,9742
TLV-TWA Exposure Limit: 3 mg/m³ (ACGIH, OSHA, NIOSH)
FDA 21 CFR: 175.105
FDA UNII: YZE19Z66EA
EPA Substance Registry System: Triphenyl phosphate (115-86-6)
EWG's Food Scores: 5
Additional Information
InChIKey: XZZNDPSIHUTMOC-UHFFFAOYSA-N
CAS DataBase Reference: 115-86-6
BRN: 1888236



FIRST AID MEASURES of TRIPHENYL PHOSPHATE (TPP):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of TRIPHENYL PHOSPHATE (TPP):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TRIPHENYL PHOSPHATE (TPP):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TRIPHENYL PHOSPHATE (TPP):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TRIPHENYL PHOSPHATE (TPP):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of TRIPHENYL PHOSPHATE (TPP):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available

TRIPROPYLENE GLYCOL, N° CAS : 24800-44-0, Nom INCI : TRIPROPYLENE GLYCOL, Nom chimique : Propanol, [(1-methyl-1,2-ethanediyl)bis(oxy)]bis-, N° EINECS/ELINCS : 246-446-0 Classification : Glycol, Ses fonctions (INCI), Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la rancidité, Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion, Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau

TRIPOTASSIUM CITRATE MONOHYDRATE = TRIPOTASSIUM CITRATE = TPC


CAS Number: 6100-05-6
EC-Number : 212-755-5
MDL number: MFCD00150442
E Number: E332
Empirical Formula (Hill Notation): C6H5K3O7 · xH2O / C6H7K3O8


Tripotassium Citrate Monohydrate (also known as tripotassium citrate) is a potassium salt of citric acid.
Tripotassium Citrate Monohydrate is a white, hygroscopic crystalline powder.
Tripotassium Citrate Monohydrate is odorless with a saline taste.
Tripotassium Citrate Monohydrate contains 38.3% potassium by mass.


Tripotassium Citrate Monohydrate is white/clear crystalline powder
Tripotassium Citrate Monohydrate is transparent prismatic crystals or a white, granular powder.
Tripotassium Citrate Monohydrate is hygroscopic and odorless, and has a cooling, saline taste.
In the monohydrate form Tripotassium Citrate Monohydrate is highly hygroscopic and deliquescent.


Tripotassium Citrate Monohydrate is a hydrate that is the monohydrate form of potassium citrate.
Tripotassium Citrate Monohydrate has a role as a diuretic.
Tripotassium Citrate Monohydrate contains a potassium citrate (anhydrous).
Tripotassium Citrate Monohydrate is the potassium salt form of citrate with alkalinizing property.


Following absorption, potassium citrate causes increased plasma bicarbonate concentration, thereby raising blood and urinary pH.
A simultaneous decrease in calcium ion activity occurs as a result of increasing calcium complex formation with dissociated anions.
Levels of urinary citrate are increased due to modification of the renal handling of citrate.
By promoting excretion of free bicarbonate ion and by increasing urinary pH in addition to an increased ionization of uric acid to more soluble urate ions, this agent exerts the alkalizing and anti-urolithic effect.


Tripotassium Citrate Monohydrate is powder that dissolves in water, which is administered orally and is used as a diuretic, expectorant, systemic alkalizer, and electrolyte replenishes.
Tripotassium Citrate Monohydrate is the common tribasic potassium salt of citric acid, also known as potassium citrate.
Tripotassium Citrate Monohydrate is produced by complete neutralization of citric acid with a high purity potassium source and subsequent crystallisation.


Tripotassium Citrate Monohydrate reduces sensitivity of teeth in oral care products.
Tripotassium Citrate Monohydrate is a non-toxic, slightly alkaline salt with low reactivity.
Tripotassium Citrate Monohydrate is chemically stable if stored at ambient temperatures.
In Tripotassium Citrate Monohydrate's monohydrate form it is very hygroscopic and must be protected from exposure to humidity.


Tripotassium Citrate Monohydrate occurs as transparent crystals or a white, granular powder.
Tripotassium Citrate Monohydrate is an odourless substance with a cooling, salty taste.
Tripotassium Citrate Monohydrate is slightly deliquescent when exposed to moist air, freely soluble in water and almost insoluble in ethanol (96%).
Tripotassium Citrate Monohydrate is one of the popular food additives and ingredients in most countries.


Tripotassium Citrate Monohydrate is the common tribasic potassium salt of citric acid, also known as potassium citrate.
Tripotassium Citrate Monohydrate is produced by complete neutralisation of citric acid with a high purity potassium source and subsequent crystallisation.
Tripotassium Citrate Monohydrate is one of the three potassium salts of citric acid.
Tripotassium Citrate Monohydrate appears as white crystalline powder with a salty taste.


Tripotassium Citrate Monohydrate is slightly deliquescent when in contact with moisture.
Tripotassium Citrate Monohydrate is very soluble in water and almost insoluble in ethanol.
Tripotassium Citrate Monohydrate is very hygroscopic and must be protected from humidity.
Tripotassium Citrate Monohydrate is non-toxic and fully biodegradable.


Tripotassium Citrate Monohydrate is a slightly alkaline salt with low reactivity at ambient temperatures.
Tripotassium Citrate Monohydrate is widely distributed in plants and in animal tissues and fluids and exist in greater than grace amounts in variety of fruits and vegetables, most notably in citrus fruits such as lemon and limes.
Tripotassium Citrate Monohydrate is also a metabolite of Dimethyl Fumarate (D464965), a compound.
Tripotassium Citrate Monohydrate is a source of citric acid, which is an alpha-hydroxy acid.


Tripotassium Citrate Monohydrate is widely distributed in plants and in animal tissues and fluids and exist in greater than grace amounts in variety of fruits and vegetables, most notably in citrus fruits such as lemon and limes.
Tripotassium Citrate Monohydrate is a hydrate that is the monohydrate form of potassium citrate.
Tripotassium Citrate Monohydrate is a potassium salt that has been reported to be efficient in forming aqueous two-phase system (ATPS) with UCON 50-HB-5100, a random copolymer.


Tripotassium Citrate Monohydrate is a sequestrant and buffer that exists as crystals or powder.
Tripotassium Citrate Monohydrate is slightly hygroscopic and possesses the advantageous properties of citric acid without having its acid reaction.
a 1% solution has a ph of 7.5–9.0.
Tripotassium Citrate Monohydrate reacts with metal ions such as calcium, magnesium, and iron to form a complex.


Tripotassium Citrate Monohydrate is soluble in water with a solubility of 1.8 g in 1 ml of 20°c water and 2 g in 1 ml of 80°c water.
Tripotassium Citrate Monohydrate is also termed tripotassium citrate.
Tripotassium Citrate Monohydrate is soluble in water and glycerol.
Tripotassium Citrate Monohydrate is insoluble in alcohol


Tripotassium Citrate Monohydrate is soluble in 0-65ml of water, slowly soluble in 2-5ml of glycerol, insoluble in ethanol.
Tripotassium Citrate Monohydrate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms of Tripotassium Citrate Monohydrate may be considered.
Tripotassium Citrate Monohydrate is a white, granulated powder or colourless crystals.


Tripotassium Citrate Monohydrate is very easily soluble in water and hardly soluble in alcohol.
Tripotassium Citrate Monohydrate is a potassium salt of the citric acid and is formed by neutralisation of citric acid with potassium.
Tripotassium Citrate Monohydrate is a pure white granular powder and has no fillers or binders, additives or preservatives.
Tripotassium Citrate Monohydrate is created by combining Potassium Bicarbonate with Citric Acid and evaporating the solution until the granular form remains.


Tripotassium Citrate Monohydrate (also known as tripotassium citrate) is a potassium salt of citric acid with the molecular formula K3C6H5O7.
Tripotassium Citrate Monohydrate is a white, hygroscopic crystalline powder.
Tripotassium Citrate Monohydrate is odorless with a saline taste.
Tripotassium Citrate Monohydrate contains 38.28% potassium by mass.


In the monohydrate form Tripotassium Citrate Monohydrate is highly hygroscopic and deliquescent.
Tripotassium Citrate Monohydrate has no smell.
Tripotassium Citrate Monohydrate's taste is salty and cool.
Tripotassium Citrate Monohydrate's hygroscopic.


Tripotassium Citrate Monohydrate is loss of crystal water at 180 ℃.
1 aqueous solution is alkaline to litmus, pH is about 8.5.
Tripotassium Citrate Monohydrate is white crystalline granules or powder.
1g of Tripotassium Citrate Monohydrate is soluble in 0.65mL water, slowly soluble in 2.5ml glycerol, insoluble in ethanol.


Tripotassium Citrate Monohydrate's aqueous solution is alkaline to litmus.
The pH value of Tripotassium Citrate Monohydrate is about 8.5.
Tripotassium Citrate Monohydrate has loss of water of crystallization at 180 °c.
As a food additive, Tripotassium Citrate Monohydrate is used to regulate acidity and is known as E number E332.



USES and APPLICATIONS of TRIPOTASSIUM CITRATE MONOHYDRATE:
Tripotassium Citrate Monohydrate is rapidly absorbed when given by mouth and is excreted in the urine.
Since Tripotassium Citrate Monohydrate is an alkaline salt it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine.
Tripotassium Citrate Monohydrate is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic.


Tripotassium Citrate Monohydrate is used food, Beverages, Tablets, Personal Care and Technical Applications.
In food industry: Tripotassium Citrate Monohydrate is used buffering agent, chelating agent, yeast food, emulsifying salt, and synergistic agent of anti-oxidation.
In chemical industry: Tripotassium Citrate Monohydrate is used tripotassium phosphate is used in the manufacture of liquid soap, refined gasoline, high-quality paper, metal surface treatment, biological hydration treatment, phosphorus-potassium fertilizers.


Tripotassium Citrate Monohydrate is the common tribasic potassium salt of citric acid, also known as potassium citrate.
Tripotassium Citrate Monohydrate is used in foods, beverages, personal care and technical applications as buffering, sequestering or emulsifying agent.
Tripotassium Citrate Monohydrate usually replaces trisodium citrate whenever a low sodium content is desired.
Tripotassium Citrate Monohydrate is used in foods, beverages, and technical applications as buffering, sequestering or emulsifying agent.


Tripotassium Citrate Monohydrate usually replaces trisodium citrate whenever a low sodium content is desired.
In pharmaceuticals Tripotassium Citrate Monohydrate is used as potassium source and as active ingredient to treat urinary duct stones.
When added to oral care products, Tripotassium Citrate Monohydrate is the active ingredient to reduce the sensitivity of the teeth.
In contrary to other potassium salts, Tripotassium Citrate Monohydrate is less bitter and thus can be used at higher concentration levels.


The food-approved substance is safe and easy in handling.
Furthermore, Tripotassium Citrate Monohydrate is one of the few fully biodegradable and non-toxic flame retardants.
Tripotassium Citrate Monohydrate is used in food and beverage industries.
Tripotassium Citrate Monohydrate finds application as buffering, sequestering or emulsifying agent.


Tripotassium Citrate Monohydrate is also used as a potassium source in pharmaceuticals and an active ingredient to treat urinary duct stones.
Tripotassium Citrate Monohydrate is added to oral care products to reduce the teeth sensitivity.
Tripotassium Citrate Monohydrate is used in foods, beverages, cosmetics, agrochemicals and as buffering agents and emulsifying agents.
Tripotassium Citrate Monohydrate is used in place of Sodium Citrate where low sodium content is required.


Tripotassium Citrate Monohydrate is used in manufacturing method of printed circuit board for autonomous vehicle to perform recognition, judgment, determination and execution.
Tripotassium Citrate Monohydrate is a weak organic acid that is known as a commodity chemical, as more than a million tonnes are produced every year by mycological fermentation on an industrial scale using crude sugar solutions, such as molasses and strains of Aspergillus niger.


Tripotassium Citrate Monohydrate is mainly used as an acidifier, flavoring agent and chelating agent.
Tripotassium Citrate Monohydrate is used in the laboratory as a buffering agent and chelator.
In renal function studies, potassium citrate is used as an alkanizing agent where the citric acid is a metabolic substrate in renal cells.
Studies have shown that potassium citrate may increase bone density, it is therefore used in research experiments related to the treatment of osteoporosis.


Tripotassium Citrate Monohydrate is used in foods, beverages, and other applications as a buffering, sequestering or emulsifying ingredient.
Tripotassium Citrate Monohydrate is the potassium salt of citric acid and it usually replaces trisodium citrate whenever a low sodium content is desired.
An organic acid naturally found in citrus fruits, Tripotassium Citrate Monohydrate is a natural preservative and is also used to add an acidic (sour) taste to foods and soft drinks.


Tripotassium Citrate Monohydrate can be added to ice cream to keep fat globules separated and be added to recipes in place of fresh lemon juice.
Tripotassium Citrate Monohydrate used in food industry, pharmaceutical industry and laboratory analytical reagents.
In the food industry Tripotassium Citrate Monohydrate can be used as buffer, chelating agents, stabilizer etc.
Tripotassium Citrate Monohydrate can be used for milk and dairy products, jellies, jams, meat, cheese emulsification, citrus preservation etc.


In the pharmaceutical industry Tripotassium Citrate Monohydrate’s used for hypokalaemia, potassium deficiency and alkaline urine.
Tripotassium Citrate Monohydrate can also be used for chemical analysis reagent.
Tripotassium Citrate Monohydrate is found in artificially sweetened jelly and in certain milk and meat products.
Tripotassium Citrate Monohydrate uses include processed cheese, pud- dings, and dietetic foods in which sodium is undesirable.


Tripotassium Citrate Monohydrate is used in foods and beverages as buffering, sequestering or emulsifying agent.
Tripotassium Citrate Monohydrate is used in manufacturing method of printed circuit board for autonomous vehicle to perform recognition, judgment, determination and execution.
Tripotassium Citrate Monohydrate is a weak organic acid that is known as a commodity chemical, as more than a million tonnes are produced every year by mycological fermentation on an industrial scale using crude sugar solutions, such as molasses and strains of Aspergillus niger.


Tripotassium Citrate Monohydrate is mainly used as an acidifier, flavoring agent and chelating agent.
Tripotassium Citrate Monohydrate is used in beverages, foods, and oral pharmaceutical formulations as a buffering and alkalizing agent.
Tripotassium Citrate Monohydrate is also used as a sequestering agent and as a therapeutic agent to alkalinize the urine and to relieve the painful irritation caused by cystitis.
Tripotassium Citrate Monohydrate is used in food (sequestrant, emulsifier, and stabilizer) and in medicine as an alkalinizing agent and antiurolithic.


Tripotassium Citrate Monohydrate is used as a flavoring agent, nutritional supplement, pH control agent, and sequestrant for foods
Tripotassium Citrate Monohydrate is used in food industry (E-332), antioxidant, preservative agent, laboratory reagent, in pharma industry.
Tripotassium Citrate Monohydrate is used as a flavoring, stabilizing agent and acidulant in food Industry.
Tripotassium Citrate Monohydrate is also used as an alkalizing agent in the treatment of mild urinary tract infections such as cystitis.


Tripotassium Citrate Monohydrate is used as a pharmaceutical aid in veterinary practice.
Tripotassium Citrate Monohydrate is also used in many pharmacopoeia and other preparations like potassium hydroxide solution, Cresol solution, Soap solution etc.
Tripotassium Citrate Monohydrate works as a buffer for juices like real, R-cola etc
Tripotassium Citrate Monohydrate is used in food, beverage, cosmetics, and many other applications.


Tripotassium Citrate Monohydrate is used in buffer solution preparation, electroplating and pharmaceutical industry.
Medicinally, Tripotassium Citrate Monohydrate may be used to control kidney stones derived from either uric acid or cystine.
Tripotassium Citrate Monohydrate is an effective way to treat/manage gout and arrhythmia if the patient is hypokalemic.
Tripotassium Citrate Monohydrate is widely used to treat urinary calculi (kidney stones) and is often used by patients with cystinuria.


A study of 500 patients with recurrent stones found that it reduced the frequency of stones from 2 per year to a half per year.
Tripotassium Citrate Monohydrate is also used as an alkanizing agent in the treatment of mild urinary tract infections such as cystitis.
Tripotassium Citrate Monohydrate is also used in many soft drinks as a buffering agent.
Tripotassium Citrate Monohydrate is a food additive and has other household and health uses as well.
Tripotassium Citrate Monohydrate may be added to foods and beverages or smoothies and green drinks.


Tripotassium Citrate Monohydrate provides bright plate in alkaline baths.
Tripotassium Citrate Monohydrate may act as sequestering agent in some metal plating
Tripotassium Citrate Monohydrate is used to adjust pH and forms metallic complexes in photo chemicals
Tripotassium Citrate Monohydrate is used as a buffer, sequestrant or emulsifier.
Tripotassium Citrate Monohydrate is used as a source of potassium in pharmaceuticals and an active ingredient for the treatment of urinary tract stones.



BENEFITS of TRIPOTASSIUM CITRATE MONOHYDRATE:
*Provides overall health and wellness
*Promotes healthy skin, hair, and nails
*Used to increase blood flow and circulation
*Stabilizes naturally produced chemicals in the body
*USP Grade Powder – 100% Pure



PRODUCTION METHODS of TRIPOTASSIUM CITRATE MONOHYDRATE:
Tripotassium Citrate Monohydrate is prepared by adding either potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases.
The resulting solution is then filtered and evaporated to dryness to obtain Tripotassium Citrate Monohydrate.



FUNCTIONS of TRIPOTASSIUM CITRATE MONOHYDRATE:
1. Acidity Regulator / Buffering Agent - Changes or maintains the acidity or basicity of food/cosmetics.
2. Binder / Stabilizer - Retains the physical characteristics of food/cosmetics and ensure the mixture remains in an even state.
Tripotassium Citrate Monohydrate is a potassium salt of citric acid.
Tripotassium Citrate Monohydrate is a white, hygroscopic crystalline powder.
Tripotassium Citrate Monohydrate is odorless with a saline taste.
As a food additive, potassium citrate is used to regulate acidity and is known as E number E332.
Tripotassium Citrate Monohydrate is also used in many soft drinks as a buffering agent.



PHYSICAL and CHEMICAL PROPERTIES of TRIPOTASSIUM CITRATE MONOHYDRATE:
Molecular Weight: 306.39 (anhydrous basis)
Physical state: solid
Color: white
Odor: No data available
Melting point/freezing point: 275 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 8,0 - 9,5
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,98 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Bulk density: ca.950 kg/m3
Min. Purity Spec: 99%
Physical Form (at 20°C): Solid
Melting Point: 275°C

Long-Term Storage: Store long-term in a cool, dry place
Molecular Weight: 324.41
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 8
Rotatable Bond Count: 2
Exact Mass: 323.9052116
Monoisotopic Mass: 323.9052116
Topological Polar Surface Area: 142 Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 211
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes
Water Solubility: 39.4 mg/mL
logP: -0.7
logP: -1.3
logS: -0.89
pKa (Strongest Acidic): 3.05
pKa (Strongest Basic): -4.2
Physiological Charge: -3
Hydrogen Acceptor Count: 7
Hydrogen Donor Count: 1
Polar Surface Area: 140.62 Å2

Rotatable Bond Count: 5
Refractivity: 68.14 m3·mol-1
Polarizability: 14.23 Å3
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Melting point: 275 °C (dec.)(lit.)
Density: 1.98

storage temp.: Inert atmosphere,Room Temperature
solubility: H2O: 1 M at 20 °C, clear, colorless
form: Granular
Specific Gravity: 1.98
color: White crystalline
Odor: Odorless
PH Range: 8 - 9.5
PH: 7.5-9.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water and glycerol.
Practically insoluble in alcoholSoluble in water and glycerol.
Insoluble in alcohol
Merck: 14,7623
BRN: 3924344
Stability: Stable.



FIRST AID MEASURES of TRIPOTASSIUM CITRATE MONOHYDRATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TRIPOTASSIUM CITRATE MONOHYDRATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of TRIPOTASSIUM CITRATE MONOHYDRATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TRIPOTASSIUM CITRATE MONOHYDRATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TRIPOTASSIUM CITRATE MONOHYDRATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Dry.



STABILITY and REACTIVITY of TRIPOTASSIUM CITRATE MONOHYDRATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Possibility of hazardous reactions:
no information available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
tri-Potassium citrate monohydrate
Tripotassium citrate
Citric acid potassium salt
2-Hydroxy-1,2,3-Propanetriccarboxylic Acid
Potassium citrate monohydrate
6100-05-6
Tripotassium citrate monohydrate
UROCIT-K
Potassium citrate tribasic monohydrate
K-cit-v
Kalii citras
MFCD00150442
EE90ONI6FF
Potassium citrate (monohydrate)
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt, monohydrate
Hydroxycitric acid (tripotassium hydrate)
Potassium 2-hydroxypropane-1,2,3-tricarboxylate hydrate
INS NO.332(II)
INS-332(II)
E-332(II)
NSC-760107
CCRIS 6543
Urocit-K (TN)
potassium citrate.H2O
Citric acid, tripotassium salt, monohydrate
UNII-EE90ONI6FF
Potassium Citrate, granular
CHEMBL3989822
DTXSID8042501
POTASSIUM CITRATE
CHEBI:64746
Tripotassium 2-hydroxy-1,2,3-propanetricarboxylate monohydrate
Citric acid potassium salt monohydrate
NSC 760107
D05578
Q27133400
ADV-7103 COMPONENT POTASSIUM CITRATE MONOHYDRATE
ADV7103 COMPONENT POTASSIUM CITRATE MONOHYDRATE
Potassium citrate tribasic monohydrate, puriss., 99.5%
Potassium citrate tribasic monohydrate, cell culture tested
Potassium citrate tribasic solution, BioUltra, 1 M in H2O
Potassium citrate tribasic monohydrate, >=98% (GC/titration)
Potassium citrate tribasic monohydrate, purum p.a., >=99.0% (NT)
Potassium citrate tribasic monohydrate, SAJ special grade, >=99.0%
Potassium citrate tribasic monohydrate, tested according to Ph.Eur.
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/1)
Potassium citrate tribasic monohydrate, meets USP testing specifications
Potassium citrate tribasic monohydrate, Vetec(TM) reagent grade, 98%
Potassium citrate, United States Pharmacopeia (USP) Reference Standard
Citric acid tripotassium salt
Tripotassium citrate
Tripotassium citrate hydrate
Tripotassium citrate monohydrate
Potassium citrate
Citric acid tripotassium salt monohydrate
Citric acid potassium salt monohydrate
Potassium citrate tribasic monohydrate
Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate monohydrate
Kalii citras
Tripotassium citrate monohydrate
Potassium citrate tribasic monohydrate
Citric acid tripotassium salt monohydrate
Tripotassium 2-hydroxypropane-1,2,3-tricarboxylate monohydrate
TRIPOTASSIUM CITRATE MONOHYDRATE
Urocit-K
Hydroxycitric acid (tripotassium hydrate)
CITRIC ACID TRIPOTASSIUM SALT MONOHYDRATE
KALII CITRAS
tri-Potassium citrate
TrikaliumcitratH2O,BP
Tri-PotassiumCitrateGr
PotassiuM Citrate (AS)
Tri-PotassiumCitrateA.R.
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt, monohydrate
Citric acid, tripotassium salt, monohydrate
Potassium citrate
Potassium citrate monohydrate
Tripotassium 2-hydroxy-1,2,3-propanetricarboxylate monohydrate
Urocit-K
K-CIT-V
Potassium citrate tribasic monohydrate
Tripotassium citrate monohydrate
Potassium 2-hydroxy-1, 2, 3-propanetricarboxylate hydrate (3:1:1)
1, 2, 3-propanetricarboxylic acid, 2-hydroxy-, potassium salt, hydrate (1:3:1)
2-Hydroxy-1, 2, 3-propanetricarboxylic acid tripotassium salt monohydrate
Potassium 2-hydroxypropane-1, 2, 3-tricarboxylate hydrate (3:1:1)
Citric acid tripotassium salt
KALII CITRAS
TRI-POTASSIUM CITRATE H2O
POTASSIUM CITRATE TRIBASIC
POTASSIUM CITRATE-1-HYDRATE
Potassium citrate monohydrate
POTASSIUM CITRATE, MONOHYDRATE
TRIPOTASSIUM CITRATE MONOHYDRATE
tripotassium citrate monohydrate
tri-Potassium citrate monohydrate
POTASSIUM CITRATE TRIBASIC HYDRATE
POTASSIUM CITRATE, TRIBASIC MONOHYDRATE
Potassium citrate, tribasic monohydrate
citric acid tripotassium cell culture*tested monohydrate
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate hydrate
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate monohydrate

Tributoxy Ethyl Phosphate; Tri-butoxyethyl phosphate; TRIBUTOXYETHYL PHOSPHATE;Phosphoric acid, tributoxyethyl ester; TRIS(2-BUTOXYETHYL) PHOSPHATE, N° CAS : 78-51-3, Nom INCI : TRIS(2-BUTOXYETHYL) PHOSPHATE; Noms français : 2-BUTOXYETHANOL PHOSPHATE (3:1); 2-BUTOXYETHANOL, PHOSPHATE; PHOSPHATE DE TRI(BUTOXY-2 ETHANOL); PHOSPHATE DE TRI(BUTOXY-2 ETHYLE); Phosphate de tri(butoxyéthyle); PHOSPHATE DE TRIS(BUTOXYETHYLE) ; PHOSPHORIC ACID, TRIS(2-BUTOXYETHYL) ESTER; TRI(2-BUTOXYETHYL) PHOSPHATE; TRIS(2-BUTOXYETHYL) PHOSPHATE. Noms anglais : ETHANOL, 2-BUTOXY-, PHOSPHATE (3:1); Tri(butoxyethyl) phosphate; TRIBUTOXYETHYL PHOSPHATE; TRIBUTOXYETHYLPHOSPHATE; TRIBUTYL CELLOSOLVE PHOSPHATE; TRIS(2-BUTOXYETHYL) ESTER OF PHOSPHORIC ACID. Utilisation et sources d'émission; Agent plastifiant, agent antimousse; Tris(2-butoxyethyl) phosphate; CAS names: Ethanol, 2-butoxy-, 1,1',1''-phosphate. IUPAC names : TBEP; Tris(2-butoxyethyl)phosphate. Trade names: 2-butoxyethanol phosphate; Kronitex KP-140; KP-140; Phosflex T-BEP; Phosflex 176C; Amgard TBEP; TBOP; TBEP; TBXP ; tri(2-butoxyethanol)phosphate; tri(2-butylethylether) phosphate; tributoxyethyl phosphate; tributyl cellosolve phosphate; tris(2-n-butoxyethyl)phosphate; tris(butylglycol) phosphate; 201-122-9 ; [EINECS]; 4-01-00-02422 (Beilstein Handbook Reference) [Beilstein]; 78-51-3 [RN]; KJ9800000; MFCD00009456; Phosphate de tris(2-butoxyéthyle) [French]; phosphoric acid tris(2-butoxyethyl) ester; Phosphoric acid, tri(butoxyethyl) ester; Phosphoric acid, tributoxyethyl ester; Phosphoric acid, tris(2-butoxyethyl) ester; Tris(2-butoxyethyl) phosphate [ACD/IUPAC Name]; Tris-(2-butoxyethyl)fosfat [Czech]; Tris(2-butoxyethyl)phosphat [German] [ACD/IUPAC Name]; tris(2-n-butoxyethyl) phosphate; 1716010 [Beilstein]; 2-butoxyethanol phosphate; 2-Butoxy-ethanol phosphate (3:1); 2-BUTOXYETHANOL PHOSPHATE (3:1); 2-Butoxyethanol, phosphate; 4O2OPO&O2O4&O2O4 [WLN]; Amgard TBEP; EINECS 201-122-9; Ethanol, 2-butoxy-, 1,1',1''-phosphate ; ETHANOL, 2-BUTOXY-, PHOSPHATE (3:1); Kronitex KP-140; NCGC00091600-02; Phosflex T-be; Phosflex T-bep; phosphoric acid tris-(2-butoxyethyl) ester; Phosphoric acid tris(2-n-butoxyethyl) ester; Phosphoric acid, tri-(2-butoxyethyl) ester; pTri(2-butoxyethanol) phosphate; TBEP; Tri(2-butoxyethanol) phosphate; Tri(2-butoxyethanol)phosphate; TRI(2-BUTOXYETHYL) PHOSPHATE TRI-(2-BUTOXYETHYL)-PHOSPHATE; Tri-(2-Butoxyethyl)phosphate (en); Tri(butoxyethyl) phosphate; TRI-2-BUTOXYETHYL PHOSPHATE; Tributoxy Ethyl Phosphate; Tri-butoxyethyl phosphate ; TRIBUTOXYETHYL PHOSPHATE; Tributyl cellosolve phosphate; Tris(2-butoxyethyl)ester phosphoric acid; Tris-(2-butoxyethyl)fosfat [Czech]; tris(2-butoxyethyl)phosphate; Tris-(2-butoxyethyl)phosphate; Tris(2-butyloxyethyl)phosphate; Tris(butoxyethyl) phosphate; Tris(butoxyethyl)phosphate; tris[2-(butyloxy)ethyl] phosphate; Tris-2-butoxyethyl phosphate; WLN: 4O2OPO&O2O4&O2O4

CAS: 57499-93-1
EC Number:259-910-3
Molecular Weight: 248.36
IUPAC Name: 1-[1-(1-butoxypropan-2-yloxy)propan-2-yloxy]propan-2-ol
Molecular Formula: C13H28O4

DESCRIPTION:
Tripropylene glycol n-butyl ether (TBPE) is a fatty acid that belongs to the group of polyoxyethylene-based nonionic surfactants.
Tripropylene glycol n-butyl ether is soluble in water and has detergent properties.
Tripropylene glycol n-butyl ether has been shown to have a high affinity for cationic surfactants, such as p-hydroxybenzoic acid, and can be used to remove them from wastewater during sewage treatment.

The toxicity of Tripropylene glycol n-butyl ether has been studied in rats and mice, showing that Tripropylene glycol n-butyl ether does not cause any significant toxic effects.
Studies have also shown that Tripropylene glycol n-butyl ether can be used as a film-forming polymer in the production of films with antimicrobial activity.
Tripropylene glycol n-butyl ether is also combined with other compounds, such as sodium citrate or dodecyl glycol ethers, to form detergent compositions for removing oil and grease from surfaces or water.
Tripropylene glycol n-butyl ether is a cleaning agent that can also be found in other laundry pre-treaters.
Tripropylene glycol n-butyl ether works by dissolving stains and soils.




CHEMICAL AND PHYSICAL PROPERTIES OF TRIPROPYLENE GLYCOL N-BUTYL ETHER:
Molecular Weight: 248.36
XLogP3-AA: 1.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 11
Exact Mass: 248.19875937
Monoisotopic Mass: 248.19875937
Topological Polar Surface Area: 47.9 Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 164
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 3
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Assay: ≥95%
refractive index: n20/D 1.432 (lit.)
bp: 276 °C (lit.)
Mp: −75 °C (lit.)
Density: 0.932 g/mL at 25 °C (lit.)
Application: Cleaners, Coatings, Inks and Adhesives
Boiling Point (°C @760mmHg): 274
CAS#: 55934-93-5
Chemical Name: Tripropylene glycol mono n-butyl ether
Density (25°C) at lb/gal (g/cc): 7.73 (0.927)
Evaporation Rate (n-butyl acetate=1.0): 0.0004
Flash Point, Closed Cup: 126 °C
Freezing Point °F(°C): Hansen Solubility Parameter, dD (joules/cm3)1/2: 14.8
Hansen Solubility Parameter, dH (joules/cm3)1/2: 7.9
Hansen Solubility Parameter, dP (joules/cm3)1/2: 1.7
Low Vapor Pressure (Molecular Weight: 248.4 g/mol
Series: P-Series
Solubility in Water (25°C): 4.5 wt%
Solubility Water in (25°C): 8 wt%
Specific Gravity (25°C):0.93
Surface Tension (1% actives, 25 °C):29.7 dynes/cm
Vapor Pressure (mmHg @ 20°C): 0.002
Viscosity (25°C):7 cP

USES OF TRIPROPYLENE GLYCOL N-BUTYL ETHER:
Tripropylene Glycol N-Butyl Ether is used in Cleaners
Tripropylene Glycol N-Butyl Ether is used in Textiles
Tripropylene Glycol N-Butyl Ether is used in Cosmetics
Tripropylene Glycol N-Butyl Ether is used in Resins
Tripropylene Glycol N-Butyl Ether is used in Coating formulation and application
Tripropylene Glycol N-Butyl Ether is used in Industrial, automotive and architectural coatings


SAFETY INFORMATION ABOUT TRIPROPYLENE GLYCOL N-BUTYL ETHER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.











SYNONYMS OF TRIPROPYLENE GLYCOL N-BUTYL ETHER:
57499-93-1
Tripropylene glycol mono-n-butyl ether
ppg-3 butyl ether
1-[1-(1-butoxypropan-2-yloxy)propan-2-yloxy]propan-2-ol
1-((1-((1-Butoxypropan-2-yl)oxy)propan-2-yl)oxy)propan-2-ol
1-({1-[(1-BUTOXYPROPAN-2-YL)OXY]PROPAN-2-YL}OXY)PROPAN-2-OL
2-Propanol, 1-(2-(2-butoxy-1-methylethoxy)-1-methylethoxy)-
2-Propanol, 1-[2-(2-butoxy-1-methylethoxy)-1-methylethoxy]-
Dowanol 66B
BRN 1704643
DOWANOL TPnB
SCHEMBL15374
DTXSID90973032
1-(2-(2-Butoxy-1-methylethoxy)-1-methylethoxy)-2-propanol
K0N34Z34O8
PPG-3 BUTYL ETHER [INCI]
POLYOXYPROPYLENE (3) BUTYL ETHER
AS-63503
POLYPROPYLENE GLYCOL (3) BUTYL ETHER
Propanol, [(butoxymethylethoxy)methylethoxy]-
5,8-Dimethyl-4,7,10-trioxatetradecane-2-ol
D93141
A905620
Q27896607
TPBGE
Dowanol TPnB
Tripropylene glycol butyl ether
((Butoxymethylethoxy)methylethoxy)propan-1-ol
Propanol, (2-(2-butoxymethylethoxy)methylethoxy)-
Tripropylene glycol (mono) n-butyl ether
1-(2-(2-Butoxy-1-methylethoxy)-1-methylethoxy)-2-propanol
DOWANOL TPNB CLYCOL ETHER
Tripropylene glycol monobutyl ether

1,3,5-tris(2-hydroxyethyl)triazine-2,4,6-trione is a white powder. Industry Uses Chemical additive used in heat stabilizers for PVC applications Flame retardants Ingredient in polyester-type resins Paint additives and coating additives not described by other categories Process regulators Processing aids, not otherwise listed Processing aids, specific to petroleum production THEIC is a white crystalline powder that is soluble in water, THF and hot lower alcohols. It is insoluble in other common organic solvents. This symmetrical triol undergoes reactions typical of unhindered, primary hydroxyl groups. Tris (2-Hydroxyethyl) isocyanurate (THEIC) is a white crystalline powder that is soluble in water. THEIC is used in coating industry for heat resistant wire enamels, electrical insulatings, alkyd resins, urethanes, water-soluble stoving enamels and polyesters. It is also used as an intermediate for the synthesis of dyes, agrochemicals, pharmaceuticals and plasticizers. Chemical Group is a long-experienced distributor of Tris (2-Hydroxyethyl) Isocyanurate.worldwide company who imports and supplies Tris (2-Hydroxyethyl) Isocyanurate in over four continents. As a supplier of Tris (2-Hydroxyethyl) Isocyanurate with a wide distribution network, customers in numerous industries rely for their supply of Tris (2-Hydroxyethyl) Isocyanurate. We have the capability and know-how as a importer, supplier, and distributor of Tris (2-Hydroxyethyl) Isocyanurate to provide your business with value-added supply chain solutions. supplies Tris (2-Hydroxyethyl) Isocyanurate to users/customers for Plastic, Resin & Rubber. This product is also known as THEIC. CAS Number 839-90-7 Formula C9-H15-N3-O6 Major Category Plastics & Rubber 1,3,5-Tris(2-hydroxyethyl) isocyanurate formula graphical representation Synonyms 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(2-hydroxyethyl)-; 1,3,5-Tris(2-hydroxyethyl) isocyanuric acid; 1,3,5-Tris(2-hydroxyethyl)isocyanuric acid; 1,3,5-Tris(2-hydroxyethyl)triazine-2,4,6-trione; Isocyanuric acid tris(2-hydroxyethyl) ester; N,N',N''-Tris(2-hydroxyethyl) isocyanurate; N,N',N''-Tris(2-hydroxyethyl)isocyanurate; THEIC; Tris(2-hydroxyethyl) isocyanurate; Tris(2-hydroxyethyl)-s-triazine-2,4,6-trione; Tris(2-hydroxyethyl)cyanurate; Tris(2-hydroxyethyl)isocyanurate; Tris(beta-hydroxyethyl) isocyanurate; Tris(hydroxyethyl) cyanurate; s-Triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-tris(2-hydroxyethyl)-; [ChemIDplus] Category Other Monomers Description White solid; [HSDB] White powder; [MSDSonline] Sources/Uses Used as a plastics additive to impart thermal stability; [HSDB] Used as a monomer to make polyesters (thermosetting varnishes and paints for metal) and as a polymer stabilizer; [Reference #1] Triazine is the chemical species of six-membered heterocyclic ring compound with three nitrogens replacing carbon-hydrogen units in the benzene ring structure. The names of the three isomers indicate which of the carbon-hydrogen units on the benzene ring position of the molecule have been replaced by nitrogens, called 1,2,3-triazine, 1,2,4-triazine, and 1,3,5-triazine respectively. Symmetrical 1,3,5-triazine is the common. Triazines are prepared from 2-azidocyclopropene through thermal rearrangement (1,2,3-triazine), from 1,2-dicarbonyl compound with amidrazone by condensation reaction (1,2,4-triazine) and from cyanic acid amide by trimerization (1,3,5-triazine). Pyridine is the aromatic nitrogen heterocycle compound having only one nitrogen, and diazines are with 2 nitrogen atoms and tetrazines are with 4 nitrogen atoms on the benzene ring system. Triazines are weak base. Triazines have much weaker resonance energy than benzene, so nucleophilic substitution is preferred than electrophilic substitution. Triazines are basic structure of herbicides, examples are amitole (CAS #: 61-82-5), atrazine (CAS #: 1912-24-9), cyanazine (CAS #: 21725-46-2), simazine (CAS #: 122-34-9), trietazine (CAS #: 1912-26-1). Large volume of triazines are used in the manufacture of resin modifiers such as melamine and benzoguanamine. Melamine (1,3,5-Triazine-2,4,6-triamine) is reacted with formaldehyde to from a very durable thermoset resin. Benzoguanamine (2,4-Diamino-6-phenyl-1,3,5-triazine) is used to increase thermoset properties of alkyd, acrylic and formaldehyde resins. Triazines are also useful as chromophore groups in colorants and Chlorine attached in Triazine compounds undergo nucleophilic substitution reactions well with with hydroxyl groups in cellulose fibres. Some triazine family compounds are used in pharmaceutical industry as coupling agent for the synthesis of peptide in solid phase as well as solution and as side chain of antibiotics. Triazine compounds are used in formulating bactericide and fungicide. They are used as preservatives in oil field applications. They are used as disinfectant, industrial deodorant and biocide in water treatment. They are used as a bleaching agents. Tris(2-hydroxyethyl) isocyanurate (THEIC) has the symmetrical triol structure and thus it can undergo polymerization reactions. It is used as a monomer for the synthesis of polyesters which are industrially used in a variety of coatings (thermosetting paints, magnet wire enamels, electrical insulating varnishes). Because of its trifunctionality, THEIC is used as a precursor to crosslinking agents for rigid urethane foams and postforming laminating resins. THEIC is used as a stabilizer and heat resistant flame retardant of polymers. One of the uses of such polymer is as exterior building material. It is also used as an intermediate for the synthesis of dyes, agrochemicals, pharmaceuticals and plasticizers.Tris (2-hydroxyethyl) isocyanurate (THEIC) was decomposed by means of chemical treatment. NMR analysis showed that the products contained large amounts of 2-oxazolidinone. The effects of potassium hydroxide as an additive, reaction temperature and time, and solvent were investigated. The decomposition of THEIC with potassium hydroxide in dimethylformamide (DMF) at 130°C for 4 hours gave a quantitative amount of 2-oxazolidinone. These results indicate that THEIC decomposed under mild reaction conditions in the presence of potassium hydroxide. DESCRIPTION AND USES Tris(2-hydroxyethyl) isocyanurate is used in costing industry for heat resistant wire enamels, electrical insulatings, alkyd resins, urethanes, water-soluble stoving enamels and polyesters. It is also used as an intermediate for the synthesis of dyes, agrochemicals, pharmaceuticals and plasticizers. APPLICATIONS Agrochemicals, Dyes, Electrical insulatings, Electronics, Enamels, Pharmaceuticals, Plastizisers, Polyesters, Resins, Alkyd, Urethanes, Wire enamel INDUSTRIES Agrochemicals, Electrical, Electronics, Pharmaceuticals PRODUCT DETAILS Product group Speciality Synonym product Tris(2-Hydroxyethyl)-s-Triazine-2,4,6-trione Package Bulk and Packed Materials Statistics number 2933-69-80(-90) Cas number 839-90-7 Cus number N/A EC number 212-660-9 RID/ADR number N/A UN number N/A Structure N/A A macromolecular homopolymer (named as Homo-THEIC) was synthesized through self-etherification of tris(2-hydroxyethyl) isocyanurate (THEIC) molecules and used as charring agent. Its chemical structure was characterized by FTIR and 13C-NMR. The charring agent was mixed with ammonium polyphosphate (APP) and applied in flame retarded polypropylene (PP). Results of UL-94, LOI, and cone calorimeter test showed that the LOI of flame retarded PP can reach 32.8% and UL-94 V-0 rating can be achieved at 30 wt % loading. The heat release rate and smoke production rate during the combustion of PP were substantially reduced. TGA results indicated that the synergistic effect between APP and Homo-THEIC existed and the addition of intumescent flame retardant (IFR) dramatically enhanced the thermal stability of PP. According to the results of TGA, SEM, TG-FTIR, FTIR, and Raman, the char forming process of IFR can be separated into three stages: the formation of viscous phosphate ester (Tonset−330 °C), the expanding process along with the decomposition of phosphate ester and the release of a large amount of gases (330–480 °C), and the final formation of graphitic-like char without any expanding feature (480–670 °C). Used as an important raw material for the production of heat-resistant wire enamels and surface coatings with extremely good mechanical properties, diverse polyurethane plastic. water-base stoving enamels. unsaturated polyester resins, As organic intermediates for insecticide, plasticizing agent, dyestuffs and phar-maceuticals etc.Tris 2-Hydroxyethyl isocyanurate (THEIC) is a white crystalline powder that is soluble in water. THEIC is used in coating industry for heat resistant wire enamels, electrically insulating, alkyd resins, urethanes, water-soluble stoving enamels, and polyesters. Product name: Tris(2-hydroxyethyl)Isocyanurate(THEIC) CAS: 839-90-7 Molecular weight: 224.2546 Molecular formula: C9H15N3O6 Applications: Used as an important raw material for the production of heat-resistant wire enamels and surface coatings with extremely good mechanical properties, diverse polyurethane plastic. water-base stoving enamels. unsaturated polyester resins, As organic intermediates for insecticide, plasticizing agent, dyestuffs and phar-maceuticals etc. A method of preparing tris(2-hydroxyethyl)isocyanurate (THEIC) is disclosed. The method comprises the step of heating a mixture of ethylene carbonate and isocyanuric acid in the presence of a catalyst at a temperature between about 160° C. and 170° C. The molar ratio of ethylene carbonate to isocyanuric acid is at least about 3 to 1, and the catalyst has at least one amine functional group. THEIC produced by the disclosed method can be used without purification as a cross-linking agent in polyester-based magnet wire enamels. In view of the problem of low combustion performance of polymer, two charring agents tris (2-hydroxyethyl) isocyanurate terephthalate ester (T-ester43 and T-ester45) with different degree of esterification were synthesized by using tris (2-hydrooxyethyl) isocyanurate (THEIC) and purified terephthalic acid (PTA) as raw materials. Two kinds of intumescent flame retardants (IFR43 and IFR45) were prepared by combination of T-ester and ammonium polyphosphate (APP).The preformed IFR were melt blended with four commercial thermoplastics to obtain flame retardant polymer blends. It is found that, after esterification, the decomposition temperature of charring agent increased up to 300℃ and char residue at 700 ℃ increases up to 10% from 1%. With 20% mass loading of IFR43 into PA6, PET, PLA, and PP, the char residue increased by 14.97%, 9.69%, 11.59%, and 7.25%, respectively. Correspondingly, the limiting oxygen index (LOI) value of polymers enhanced by 6%~7%. The melt drops during LOI test decreased. In addition, crystallization acceleration effect is found in the sample of PLA after addition of IFR. THEIC is mainly be used as an important raw material for the production of heat-resistant wire enamels and PVC heat stabilizer for improving the heat-resistant of wire enamels and PVC processing temperature and performance. Besides these two major application, THEIC also be used in the production of various polyurethane plastics, water-based baking lacquer, unsaturated polyester resins, pesticide, plastic accelerator, dye staffs and intermediate for organic synthesis. Tris (2-Hydroxyethyl) isocyanurate (THEIC) is a white crystalline powder that is soluble in water. THEIC is used in coating industry for heat resistant wire enamels, electrical insulatings, alkyd resins, urethanes, water-soluble stoving enamels and polyesters. It is also used as an intermediate for the synthesis of dyes, agrochemicals, pharmaceuticals and plasticizers. 1,3,5-Tris(2-hydroxyethyl)isocyanurate (THEIC) is a triazine derivative with three nitrogen atoms in its structure. It can be used as a stabilizer and can be a useful material in applications that require flame-retardancy and water durability. THEIC can be used to functionalize graphene magnetic nanoparticles to form a catalyst that facilitates the synthesis of benzimidazole compounds.[2] It may also be used in the synthesis of hyperbranched epoxy resin by UV-initiated thiolene click reaction, which finds potential application in the fabrication of insulating materials. Tris 2-hydroxyethyl isocyanurate. Derived from cyanuric acid (1, 3, 5-triazine-2, 4, 6-triol) which is a cyclic trimer. It is usually a white, odorless solid. Used as a raw material for synthetic resins. THEIC, also known as Tris (2-Hydroxyethyl) Isocyanurate, has applications in modified polyimide insulating varnish, paint for the base plate of automobiles, the manufacture of high-quality heat-resisting alcohol acid and plasticizer, and in the printing, textile, plastics, and photo industries.

Tris(2-Butoxyethyl) Phosphate is an organic flame retardant.
Tris(2-Butoxyethyl) Phosphate is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.


CAS Number: 78-51-3
EC Number: 201-122-9
MDL number: MFCD00009456
Linear Formula: [CH3(CH2)3OCH2CH2O]3P(O)
Molecular Formula: C18H39O7P



SYNONYMS:
TBEP, TRI(BUTOXYETHYL)PHOSPHATE, TRIS(BUTOXYETHYL) PHOSPHATE, TBXP, kp140, KP 140, KP-140, 2-butoxy, Amgard TBEP, phosflext-bep, tris 2-butoxyethyl phosphate, tbep, phosflex t-bep, tris butoxyethyl phosphate, tributoxyethyl phosphate, tri butoxyethyl phosphate, kronitex kp-140, tributyl cellosolve phosphate, ethanol, 2-butoxy-, phosphate 3:1, tri 2-butoxyethyl phosphate, 2-Butoxyethanol, phosphate, Ethanol, 2-butoxy-, phosphate (3:1), KP 140, Kronitex KP-140, Phosflex T-BEP, Phosphoric acid, tributoxyethyl ester, Phosphoric acid, tris(2-butoxyethyl) ester, TBEP, Tri(2-butoxyethanol) phosphate, Tri(2-butoxyethanol)phosphate, Tributoxyethyl phosphate, Tributyl cellosolve phosphate, Tris(2-butoxyethyl) phosphate, Tris(butoxyethyl) phosphate, Tris-(2-butoxyethyl)fosfat, Tbep, Tris(Butoxyethyl)Phosphate, Phosflex T-Bep, Kronitex Kp-140, Tributyl Cellosolve Phosphate, Tri(2-Butoxyethanol)Phosphate, Tris-(2-Butoxyethyl)Fosfat, Tributoxyethyl phosphate, Phosphoric acid, tris(2-butoxyethyl) ester, Tris(butoxyethyl)phosphate, Phosphoric acid, tributoxyethyl ester, Tris[2-(butyloxy)ethyl] phosphate, Phosphoric acid tris(2-butoxyethyl) ester, Phosflex T-bep, Kronitex KP-140, 2-Butoxyethanol phosphate, KP 140, Phosphoric acid, tributoxyethyl ester, Tri(butoxyethyl) phosphate, Tri(2-butoxyethyl) phosphate, Tributyl cellosolve phosphate, Tris(butoxyethyl) phosphate, Tris(2-butoxyethyl) phosphate, TBEP, Phosphoric acid, tris(2-butoxyethyl) ester, 2-Butoxyethanol phosphate, Kronitex KP-140, Phosflex T-bep, Tri(2-butoxyethanol)phosphate, Tris-(2-butoxyethyl)fosfat, 2-Butoxy-ethanol phosphate (3:1), Amgard TBEP, Tris(2-butoxyethyl)ester phosphoric acid, Phosphoric acid, tri-(2-butoxyethyl) ester, Ethanol, 2-butoxy-, 1,1',1''-phosphate, NSC 4839, 31227-66-4, 19040-50-7, Phosphoric acid tris(2-butoxyethyl) ester, Tris(2-butoxyethyl) phosphate, 78-51-3, TBEP, Tributoxyethyl phosphate, TRI(2-BUTOXYETHYL) PHOSPHATE, Phosflex T-bep, Tris(butoxyethyl) phosphate, tris(2-butoxyethyl)phosphate, KP 140, Kronitex KP-140, Tributyl cellosolve phosphate, Ethanol, 2-butoxy-, phosphate (3:1), Tri(butoxyethyl) phosphate, Phosphoric acid, tributoxyethyl ester, Phosphoric acid, tris(2-butoxyethyl) ester, Tri(2-butoxyethanol)phosphate, NSC 4839, Tris-(2-butoxyethyl)fosfat, Phosphoric Acid Tris(2-butoxyethyl) Ester, 2-Butoxyethanol phosphate, Tris(butoxyethyl)phosphate, Ethanol, 2-butoxy-, 1,1',1''-phosphate, DTXSID5021758, CHEBI:35038, RYA6940G86, tris[2-(butyloxy)ethyl] phosphate, NSC-4839, TBEP; KP 140; Hostaphat B 310, NSC-62228, Phosphoric acid, tri-(2-butoxyethyl) ester, Ethanol, phosphate (3:1), Tris(2-butyloxyethyl)phosphate, DTXCID201758, WLN: 4O2OPO&O2O4&O2O4, 2-Butoxyethanol, phosphate, CAS-78-51-3, Phosphoric acid, tri(butoxyethyl) ester, TBOEP, CCRIS 5942, Tri(2-butoxyethanol) phosphate, HSDB 2564, 2-Butoxyethanol phosphate (3:1), EINECS 201-122-9, Tris(2-butoxyethyl) phosphate, C18H39O7P, 78-51-3, BRN 1716010, tris-2-butoxyethyl phosphate, UNII-RYA6940G86, AI3-04596, Amgard TBEP, MFCD00009456, EC 201-122-9, NCIOpen2_007840, SCHEMBL37268, 4-01-00-02422 (Beilstein Handbook Reference), Tri-(2-Butoxyethyl)phosphate, BIDD, CHEMBL1534811, NSC4839, NSC62228, 2-Butoxy-ethanol phosphate (3:1), Tox21_201593, Tox21_302891, Tris(2-butoxyethyl) phosphate, 94%, AKOS015839670, NCGC00091600-01, NCGC00091600-02, NCGC00091600-03, NCGC00256553-01, NCGC00259142-01, Tris(2-butoxyethyl)ester phosphoric acid, AS-59809, Phosphoric acid tris(2-n-butoxyethyl)ester, CS-0066127, FT-0689063, NS00010389, P0683, Phosphoric acid tris(2-n-butoxyethyl) ester, TRI(2-BUTOXYETHYL) PHOSPHATE [HSDB], F71229, A915093, Tris(2-butoxyethyl) phosphate, analytical standard, W-104277, Q27116378, Tris(2-butoxyethyl) phosphate, tri(butoxyethyl)phosphate, KP-140, TBEP, Phosphoric acid tris(2-Butoxyethyl)ester, 2-butoxy-ethanol phosphate (3:1), Tris(2-butoxyethyl)phosphate, TBEP, 2-butoxy, 2-Butoxy-ethanol phosphate (3:1), 2-Butoxy-ethanolphosphate(3:1), 2-butoxy-ethanophosphate(3:1), Amgard TBEP, Ethanol, 2-butoxy-, phosphate (3:1), tri(butoxyethyl), TBXP, TBEP, KP-140, Tributoxy Ethyl Phosphate, Tris(butoxyethyl) Phosphate, Tris(2-butoxyethyl)phosphate, Tris(2-butoxyethyl) phosphate, Phosphoric acid tris(2-n-butoxyethyl) ester, 2-BUTOXYETHANOL PHOSPHATE, PHOSPHORIC ACID TRIS (2-N-BUTOXYETHYL) ESTER, PHOSPHORIC ACID TRIS (2-BUTOXYETHYL) ESTER, TBEP, TRI (BUTOXYETHYL) PHOSPHATE, TRIS (BUTOXYETHYL) PHOSPHATE, TRIS (2-BUTOXYETHYL) PHOSPHATE, 2-Butoxy, Phosphoric acid, tri-(2-butoxyethyl) ester, Tributoxyethyl phosphate, 2-Butoxyethanol phosphate, Ethanol, 2-butoxy-, phosphate (31), TBEP, Tris (2-butoxyethyl) phosphate



Tris(2-Butoxyethyl) Phosphate acts as an additive flame retardant and plasticizer in plastics and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate appears as a colorless clear liquid having molecular weight of 398.47.
Tris(2-Butoxyethyl) Phosphate is a phosphorothioate that is used to inhibit the activity of the enzyme polymerase chain reaction.


Tris(2-Butoxyethyl) Phosphate has been shown to induce apoptosis in vitro, which may be due to its ability to decrease mitochondrial membrane potential and interfere with signal pathways.
Tris(2-Butoxyethyl) Phosphate has not been shown to affect human serum α1-acid glycoprotein or dimethyl fumarate levels.


Tris(2-Butoxyethyl) Phosphate is an efficient inhibitor of DNA polymerase activity and mitochondrial DNA synthesis in vivo, but it does not significantly affect mitochondrial membrane potential or cell proliferation.
Tris(2-Butoxyethyl) Phosphate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Tris(2-Butoxyethyl) Phosphate is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate is an organic flame retardant.
Tris(2-Butoxyethyl) Phosphate shows PXR agonistic activity.


Tris(2-Butoxyethyl) Phosphate was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.
Tris(2-Butoxyethyl) Phosphate is a slightly yellow viscous liquid.


Tris(2-Butoxyethyl) Phosphate is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate has a role as an environmental contaminant and a flame retardant.
Tris(2-Butoxyethyl) Phosphate is slightly yellow liquid with a sweetish odor.


Tris(2-Butoxyethyl) Phosphate is an organic flame retardant.
Tris(2-Butoxyethyl) Phosphate shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.



USES and APPLICATIONS of TRIS(2-BUTOXYETHYL) PHOSPHATE:
Tris(2-Butoxyethyl) Phosphate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.
Tris(2-Butoxyethyl) Phosphate is used in the following products: washing & cleaning products, polishes and waxes, plant protection products and water treatment chemicals.


Other release to the environment of Tris(2-Butoxyethyl) Phosphate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Release to the environment of Tris(2-Butoxyethyl) Phosphate can occur from industrial use: as processing aid and of substances in closed systems with minimal release.


Other release to the environment of Tris(2-Butoxyethyl) Phosphate is likely to occur from: indoor use as processing aid, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use as processing aid and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Tris(2-Butoxyethyl) Phosphate can be found in products with material based on: wood (e.g. floors, furniture, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Tris(2-Butoxyethyl) Phosphate is used in the following products: plant protection products, hydraulic fluids, lubricants and greases, metal working fluids, washing & cleaning products and polishes and waxes.


Tris(2-Butoxyethyl) Phosphate has an industrial use resulting in manufacture of another substance (use of intermediates).
Tris(2-Butoxyethyl) Phosphate is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Tris(2-Butoxyethyl) Phosphate is used for the manufacture.


Other release to the environment of Tris(2-Butoxyethyl) Phosphate is likely to occur from: outdoor use as processing aid and indoor use as processing aid.
Tris(2-Butoxyethyl) Phosphate is used in the following products: polymers and textile treatment products and dyes.
Release to the environment of Tris(2-Butoxyethyl) Phosphate can occur from industrial use: formulation in materials and formulation of mixtures.


Tris(2-Butoxyethyl) Phosphate is used in the following products: polymers, textile treatment products and dyes and washing & cleaning products.
Tris(2-Butoxyethyl) Phosphate is used for the manufacture of: plastic products and textile, leather or fur.
Release to the environment of Tris(2-Butoxyethyl) Phosphate can occur from industrial use: in the production of articles, as processing aid and in processing aids at industrial sites.


Tris(2-Butoxyethyl) Phosphate is a fire-resistant and light-stable plasticizer for food-contact products, resins & elastomers in floor finishes and waxes.
Tris(2-Butoxyethyl) Phosphate is a useful research chemical suitable for rubber stoppers in blood specimen containers.
Tris(2-Butoxyethyl) Phosphate emits toxic fumes of phosphorous oxides when heated to decomposition.


Tris(2-Butoxyethyl) Phosphate can be used as a resin solvent, plastisol viscosity modifier, and antifoam agent for synthetic rubber, plastics & lacquers.
Tris(2-Butoxyethyl) Phosphate is used as a plasticizer for resins and elastomers, in floor finishes and waxes, as a flame retardant, as a plasticizer for rubber stoppers in blood specimen containers, and as a fire-resistant and light-stable plasticizer for products intended for food contact; Occupational exposure is likely to be by skin absorption during production and from floor polishes.


Tris(2-Butoxyethyl) Phosphate is used as solvent for resins, a viscosity modifier in plastisols, and an antifoam agent for synthetic rubber, plastics, and lacquers.
Tris(2-Butoxyethyl) Phosphate is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.


The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate a real multifunctional additive essential to many polymer formulations.
Tris(2-Butoxyethyl) Phosphate is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.


Tris(2-Butoxyethyl) Phosphate is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.


Tris(2-Butoxyethyl) Phosphate may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique.
Tris(2-Butoxyethyl) Phosphate is used primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.



CHEMICAL PROPERTIES OF TRIS(2-BUTOXYETHYL) PHOSPHATE:
Tris(2-Butoxyethyl) Phosphate is slightly yellow, oily liquid.
Tris(2-Butoxyethyl) Phosphate is insoluble or limited solubility in glycerol, glycols, and certain amines; soluble in most organic liquids.



AIR AND WATER REACTIONS OF TRIS(2-BUTOXYETHYL) PHOSPHATE:
Tris(2-Butoxyethyl) Phosphate is water soluble.



REACTIVITY PROFILE OF TRIS(2-BUTOXYETHYL) PHOSPHATE:
Organophosphates, such as Tris(2-Butoxyethyl) Phosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.
Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Tris(2-Butoxyethyl) Phosphate may react with oxidizers.



PHYSICAL and CHEMICAL PROPERTIES of TRIS(2-BUTOXYETHYL) PHOSPHATE:
CAS Number: 78-51-3
Molecular Weight: 398.47
EC Number: 201-122-9
MDL number: MFCD00009456
CBNumber: CB1312263
Molecular Formula: C18H39O7P
Molecular Weight: 398.47
MDL Number: MFCD00009456
MOL File: 78-51-3.mol
Melting point: -70°C
Boiling point: 215-228 °C (4 mm Hg, lit.)
Density: 1.006 g/mL at 25 °C (lit.)
Vapor density: 13.7 (vs air)
Vapor pressure: 0.03 mm Hg (150 °C)

Refractive index: n20/D 1.438 (lit.)
Flash point: >230 °F
Storage temp.: Store at -20°C
Solubility: Chloroform (Slightly), DMSO (Slightly),
Ethyl Acetate (Slightly), Methanol (Slightly)
Form: Liquid
Color: Clear colorless to very slightly yellow
Water Solubility: Soluble
Stability: Stable.
Incompatible with strong oxidizing agents.
InChIKey: WTLBZVNBAKMVDP-UHFFFAOYSA-N
LogP: 3.75 at 20℃

CAS DataBase Reference: 78-51-3 (CAS DataBase Reference)
Indirect Additives used in Food Contact Substances: TRIBUTOXYETHYL PHOSPHATE
FDA 21 CFR: 175.105
EWG's Food Scores: 1
FDA UNII: RYA6940G86
NIST Chemistry Reference: Phosphoric acid, tri-(2-butoxyethyl) ester (78-51-3)
EPA Substance Registry System: Tris(2-butoxyethyl) phosphate (78-51-3)
Appearance Form: liquid
Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/range: < -70 °C - (ECHA)
Initial boiling point and boiling range: 215 - 228 °C at 5 hPa - lit.

Flash point: ca.159 °C at ca.1.014,6 hPa - closed cup - ISO 1523
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,04 hPa at 150 °C
Vapor density: 13,75 - (Air = 1.0)
Density: 1,006 g/cm3 at 25 °C - lit.
Relative density: 1,02 at 20 °C
Water solubility: 0,66 g/l at 25 °C
Partition coefficient: n-octanol/water log Pow: 3,75
Autoignition temperature: 322 °C at 1.013 hPa
Decomposition temperature: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 12,4 mPa.s at 20 °C
Explosive properties: No data available
Oxidizing properties: none
Surface tension: 32,7 mN/m at 20,2 °C
Relative vapor density: 13,75 - (Air = 1.0)
Appearance: colorless transparent liquid
Acidity (mgKOH/ g): ≤0.1
Refractive index (nD25): 1.4320 —1.4380
Specific gravity (20/20℃): 1.012-1.023
Color (Pt-Co): ≤ 50
Moisture: ≤0.1%
Appearance: colorless transparent liquit
Acid value(mgKOH/g): ≤0.1

Refractive index(nD25): 1.4320-1.4380
Specific gravity(20/20℃): 1.012-1.023
Chroma(Pt-Co): ≤60
Moisture(Pt-Co): ≤0.2%
Cas No: 78-42-2
Molecular Formula: C24H51O4P
Molecular Weight: 434.64
Appearance: Colorless Transparent Liquid
Molecular Formula: C18H39O7P
Molar Mass: 398.47
Melting Point: -70℃
Boling Point: 215-228℃4 mm Hg(lit.)
Water Solubility: Soluble
Appearance: Transparent liquid
Storage Condition: 2-8℃
MDL: MFCD00009456

melting point: -70°C
boiling point: 215-228 °C4mm Hg(lit.)
density: 1.006 g/mL at 25 °C(lit.)
vapor density: 13.7 (vs air)
Vapor pressure: 0.03mm Hg ( 150 °C)
refractive index: n20/D 1.438(lit.)
flash point: >230 °F
morphology: Liquid
color: Clear colorless to very slightly yellow
water solubility: Soluble
stability: Stable.
Incompatible with strong oxidizing agents.
InChIKey: WTLBZVNBAKMVDP-UHFFFAOYSA-N

Molecular Weight: 398.5 g/mol
XLogP3-AA: 2.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 7
Rotatable Bond Count: 21
Exact Mass: 398.24334058 g/mol
Monoisotopic Mass: 398.24334058 g/mol
Topological Polar Surface Area: 72.4 Ų
Heavy Atom Count: 26
Formal Charge: 0
Complexity: 281
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS Number: 78-51-3
Formula: C18H39O7P
Molecular weight: 398.48 g/mol
MDL Number: MFCD00009456
InChI Key: WTLBZVNBAKMVDP-UHFFFAOYSA-N
PubChem CID: 6540
ChEBI: CHEBI:35038
IUPAC Name: tris(2-butoxyethyl) phosphate
SMILES: CCCCOC(COCCOC)OP(=O)(OCCOCCCC)OCCOCCCC
Color: Colorless to Yellow

Density: 1.0000 g/mL
Boiling Point: 215°C to 228°C (4.0 mmHg)
Flash Point: 132°C
Infrared Spectrum: Authentic
Assay Percent Range: 94% min. (GC)
Packaging: Glass bottle
Linear Formula: [CH3(CH2)3OCH2CH2O]3P(O)
Refractive Index: 1.4370 to 1.439
Specific Gravity: 1
Solubility Information: Solubility in water: 1.3 g/L (20°C)
Formula Weight: 398.47
Percent Purity: 95%
Physical Form: Liquid
Chemical Name or Material: Tris(2-butoxyethyl) phosphate



FIRST AID MEASURES of TRIS(2-BUTOXYETHYL) PHOSPHATE:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TRIS(2-BUTOXYETHYL) PHOSPHATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions



FIRE FIGHTING MEASURES of TRIS(2-BUTOXYETHYL) PHOSPHATE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TRIS(2-BUTOXYETHYL) PHOSPHATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
*Skin protection:
not required
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TRIS(2-BUTOXYETHYL) PHOSPHATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of TRIS(2-BUTOXYETHYL) PHOSPHATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .

TCPP; Tris(1,3-dichloro-2-propyl)phosphate; Tris(2-chloro-1-(chloromethyl)ethyl)phosphate; Tris(1-chloromethyl-2-chloroethyl)phosphate; Tris(1,3-dichloroisopropyl)phosphate; Tri(beta,beta'-dichloroisopropyl)phosphate; FYROL FR 2; PF 38; Fosforan Troj-(1,3-dwuchloroizopropylowy) (Polish); 1,3-dichloro-2-propanol phosphate (3:1); cas no: 13674-87-8

Tris(2-Butoxyethyl) Phosphate (TBEP) is slightly yellow, oily liquid. Insoluble or limited solubility in glycerol, glycols, and certain amines; soluble in most organic liquids.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organophosphate flame retardant and used as a plasticizer in various household products such as plastics, floor polish, varnish, textiles, furniture, and electronic equipment.

CAS Number: 78-51-3
Molecular Formula: C18H39O7P
Molecular Weight: 398.47
EINECS Number: 201-122-9

Synonyms: Tris(2-butoxyethyl) phosphate, 78-51-3, TBEP, Tributoxyethyl phosphate, TRI(2-BUTOXYETHYL) PHOSPHATE, Phosflex T-bep, Tris(butoxyethyl) phosphate, tris(2-butoxyethyl)phosphate, KP 140, Kronitex KP-140, Tributyl cellosolve phosphate, Ethanol, 2-butoxy-, phosphate (3:1), Tri(butoxyethyl) phosphate, Phosphoric acid, tributoxyethyl ester, Phosphoric acid, tris(2-butoxyethyl) ester, Tri(2-butoxyethanol)phosphate, NSC 4839, Tris-(2-butoxyethyl)fosfat, Phosphoric Acid Tris(2-butoxyethyl) Ester, 2-Butoxyethanol phosphate, Tris(butoxyethyl)phosphate, Ethanol, 2-butoxy-, 1,1',1''-phosphate, DTXSID5021758, CHEBI:35038, RYA6940G86, tris[2-(butyloxy)ethyl] phosphate, NSC-4839, TBEP;KP 140;Hostaphat B 310, NSC-62228, Phosphoric acid, tri-(2-butoxyethyl) ester, Ethanol, phosphate (3:1), DTXCID201758, WLN: 4O2OPO&O2O4&O2O4, 2-Butoxyethanol, phosphate, CAS-78-51-3, Phosphoric acid, tri(butoxyethyl) ester, TBOEP, CCRIS 5942, Tri(2-butoxyethanol) phosphate, HSDB 2564, 2-Butoxyethanol phosphate (3:1), EINECS 201-122-9, Tris-(2-butoxyethyl)fosfat [Czech], Tris(2-butoxyethyl) phosphate,C18H39O7P,78-51-3, BRN 1716010, tris-2-butoxyethyl phosphate, UNII-RYA6940G86, AI3-04596, Amgard TBEP, MFCD00009456, EC 201-122-9, NCIOpen2_007840, SCHEMBL37268, 4-01-00-02422 (Beilstein Handbook Reference), Tri-(2-Butoxyethyl)phosphate, BIDD:ER0626, Tris(2-butyloxyethyl)phosphate, CHEMBL1534811, NSC4839, NSC62228, 2-Butoxy-ethanol phosphate (3:1), Tox21_201593, Tox21_302891, Tris(2-butoxyethyl) phosphate, 94%, AKOS015839670, NCGC00091600-01, NCGC00091600-02, NCGC00091600-03, NCGC00256553-01, NCGC00259142-01, Tris(2-butoxyethyl)ester phosphoric acid, AS-59809, Phosphoric acid tris(2-n-butoxyethyl)ester, CS-0066127, NS00010389, P0683, Phosphoric acid tris(2-n-butoxyethyl) ester, TRI(2-BUTOXYETHYL) PHOSPHATE [HSDB], F71229, A915093, Tris(2-butoxyethyl) phosphate, analytical standard, W-104277, Q27116378

Tris(2-Butoxyethyl) Phosphate (TBEP) is an organophosphate compound used primarily as a flame retardant and plasticizer in various industrial applications.
Its chemical formula is C18H39O7P, and its CAS number is 78-51-3.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly utilized in the production of plastics, polymers, adhesives, and coatings to enhance their flexibility and flame resistance properties.

Additionally, Tris(2-Butoxyethyl) Phosphate (TBEP) finds application as a component in hydraulic fluids, lubricants, and as a solvent in some chemical processes.
Tris(2-Butoxyethyl) Phosphate (TBEP), also known as TBEP, is a type of flame retardant that is commonly used in various industries such as plastics, rubber, textiles, and electronics.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a colorless and odorless liquid that is soluble in water, ethanol, and other organic solvents.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a type of organophosphate ester, which means that it is derived from the reaction between phosphoric acid and alcohol.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a versatile flame retardant that has several advantages compared to other types of flame retardants.
One of the main advantages of Tris(2-Butoxyethyl) Phosphate (TBEP) is its high efficiency in reducing the flammability of materials.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a halogen-free flame retardant, which means that it does not contain any bromine or chlorine compounds that are known to be harmful to the environment and human health.
Tris(2-Butoxyethyl) Phosphate (TBEP) works by forming a protective layer on the surface of the material, which prevents the spread of fire.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.

Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes Tributoxy ethyl phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a light-colored, high-boiling, non-flammable viscous liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is generally used as a plasticizer in rubber and plastics, and aids in floor polish formation (as well as in other surface coatings),
leveling and improves gloss.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a clear, colorless liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphine oxide and thus very stable in nature.
Tris(2-Butoxyethyl) Phosphate (TBEP) has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, “knockdown” defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used to add flexibility in vinyl resins, other plastics, natural and synthetic rubbers, and floor finishes and waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a flame-retardant plasticizer.
Tris(2-Butoxyethyl) Phosphate (TBEP) is mainly used for flame-retardant and plasticizing of polyurethane resin, cellulose, polyvinyl alcohol, etc.

Tris(2-Butoxyethyl) Phosphate (TBEP) has good low-temperature characteristic.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be obtained by the reaction of the reaction of phosphorus oxychloride and 2-butoxyethanol .
Tris(2-Butoxyethyl) Phosphate (TBEP) is a flammable, hardly inflammable, colorless to yellowish liquid that is sparingly soluble in water.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as an organic flame retardant , as well as in floor care products, as a solvent in resins, as a viscosity modifier in plastisols and as a plasticizer in rubber stoppers.
Tris(2-Butoxyethyl) Phosphate (TBEP)is mainly used as floor polishing agent and processing agent of water-based adhesive, flame retardant and plasticizer of acrylonitrile type rubber, cellulose acetate, epoxy resin, ethyecellulose, polyvinyl acetate, thermoplastic and thermosetting polyurethane.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used as defoamer in coating, detergent and textiles.

Moreover, Tris(2-Butoxyethyl) Phosphate (TBEP) can be also used in nitrocellulose, ethyecellulose and acrylic plastic plasticizer.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a chemical compound commonly used as a flame retardant and plasticizer in various industrial products.
Tris(2-Butoxyethyl) Phosphate (TBEP) is added to materials like plastics, rubber, and textiles to make them less flammable and more flexible.

Tris(2-Butoxyethyl) Phosphate (TBEP) can also be found in hydraulic fluids, lubricants, and as a solvent in certain chemical processes.
While it provides important functional properties to these products, concerns have been raised about its potential environmental and health impacts.
Tris(2-Butoxyethyl) Phosphate (TBEP) has been studied for its persistence in the environment and possible toxicity to aquatic organisms.

As a result, regulations and guidelines regarding its use and disposal may vary depending on the region.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used as a halogen free flame retardant additive in polymer systems.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used also in conjunction with other flame retardants.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a light-colored, high-boiling, non-flammable viscous liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is generally used as a plasticizer in rubber and plastics, and aids in floor polish formation (as well as in other surface coatings), leveling and improves gloss.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a plasticizer for polyvinyl chloride (PVC), chlorinated rubber and nitriles.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also an alkyl phosphate flame retardant and has good heat stability.

Tris(2-Butoxyethyl) Phosphate (TBEP) can be used in applications needing low temperature flexibility such as a leveling agent for acrylic resin-based polishes.
Tris(2-Butoxyethyl) Phosphate (TBEP) can also be used for emulsions of floor finishes, leveling agent in latex paint, a processing aid for acrylonitrile rubber, antiblock agent for cast polyurethanes.
As a plasticizer, Tris(2-Butoxyethyl) Phosphate (TBEP) incorporates readily and is a non-reactive, medium viscosity liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is high solvency makes it a great product for natural and synthetic resins and compatible with waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used commercially in floor polishes, paper coatings and as an antifoaming agent in ore beneficiations.
Tris(2-Butoxyethyl) Phosphate (TBEP) also finds uses in vinyl plastics.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a clear, colorless liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphine oxide and thus very stable in nature.
Tris(2-Butoxyethyl) Phosphate (TBEP) has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, “knockdown” defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for polymer dispersions and also improves wetting-levelling properties of drybright emulsions.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate (TBEP) has a role as an environmental contaminant and a flame retardant.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a slightly yellow viscous liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.

Tris(2-Butoxyethyl) Phosphate (TBEP) shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate (TBEP) was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Tris(2-Butoxyethyl) Phosphate (TBEP) is its compatibility with various types of polymers and resins.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used in combination with other flame retardants to enhance its effectiveness.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also compatible with other additives such as plasticizers and stabilizers, which makes it a versatile ingredient in the production of various types of materials.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also known for its thermal stability and resistance to hydrolysis.
Tris(2-Butoxyethyl) Phosphate (TBEP) can withstand high temperatures without decomposing or releasing toxic gases.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also resistant to moisture and can maintain its effectiveness even in humid environments.
Organophosphates, such as Tris(2-Butoxyethyl) Phosphate (TBEP), are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.
Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Tris(2-Butoxyethyl) Phosphate (TBEP) may react with oxidizers. .
Tris(2-Butoxyethyl) Phosphate (TBEP) acts as an additive flame retardant and plasticizer in plastics and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate (TBEP) appears as a colorless clear liquid having molecular weight of 398.47.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate (TBEP) has a role as an environmental contaminant and a flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a slightly yellow viscous liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) has been subject to regulatory scrutiny due to its potential environmental and health impacts, and its usage may be subject to restrictions in certain regions.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.

Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.

Tributoxyethyl Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.

Tris(2-Butoxyethyl) Phosphate (TBEP) shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate (TBEP) was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.
It shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate (TBEP) was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Melting point: -70°C
Boiling point: 215-228 °C4 mm Hg(lit.)
Density: 1.006 g/mL at 25 °C(lit.)
vapor density: 13.7 (vs air)
vapor pressure: 0.03 mm Hg ( 150 °C)
refractive index: n20/D 1.438(lit.)
Flash point: >230 °F
storage temp.:Store at -20°C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Liquid
color: Clear colorless to very slightly yellow
Water Solubility: Soluble
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: WTLBZVNBAKMVDP-UHFFFAOYSA-N
LogP: 3.75 at 20℃

Tris(2-Butoxyethyl) Phosphate (TBEP) is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate (TBEP) has a role as an environmental contaminant and a flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a slightly yellow viscous liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is an alkyl phosphate flame retardant and plasticizer, specifically tris(butoxyethyl) phosphate.
Tris(2-Butoxyethyl) Phosphate (TBEP) is recommended fo use as a plasticizer for PVC, chlorinated rubber and for nitrile.
Tris(2-Butoxyethyl) Phosphate (TBEP) is often used as a leveling agent in floor polishes, as a leveling agent in paints, and as an antiblock agent for cast polyurethanes.

Tris(2-Butoxyethyl) Phosphate (TBEP) exhibits low viscosity (12 cps).
Tris(2-Butoxyethyl) Phosphate (TBEP) contains 7.8% phosphorous.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a plasticizer for polyvinyl chloride (PVC), chlorinated rubber and nitriles.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also an alkyl phosphate flame retardant and has good heat stability.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used in applications needing low temperature flexibility such as a leveling agent for acrylic resin-based polishes.
Tris(2-Butoxyethyl) Phosphate (TBEP) can also be used for emulsions of floor finishes, leveling agent in latex paint, a processing aid for acrylonitrile rubber, antiblock agent for cast polyurethanes.

As a plasticizer, Tris(2-Butoxyethyl) Phosphate (TBEP), incorporates readily and is a non-reactive, medium viscosity liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP)s high solvency makes it a great product for natural and synthetic resins and compatible with waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used commercially in floor polishes, paper coatings and as an antifoaming agent in ore beneficiations.

Tris(2-Butoxyethyl) Phosphate (TBEP) also finds uses in vinyl plastics.
Tris(2-Butoxyethyl) Phosphate (TBEP) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used by consumers, in articles, by professional workers (widespread uses), in formulation or repacking and at industrial sites.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.
Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.

The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.
Tris(2-Butoxyethyl) Phosphate (TBEP) is widely used in household materials such as plasticizer, floor polish and flame retardant in plastic resins and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate (TBEP)-based is a plasticizer and defoamer.

Tris(2-Butoxyethyl) Phosphate (TBEP) also acts as a leveling agent for acrylic and styrenic floor polishes and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is valued for its effectiveness as a flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) works by reducing the flammability of materials, thereby slowing down or preventing the spread of fire.

In addition to its flame retardant properties, Tris(2-Butoxyethyl) Phosphate (TBEP) acts as a plasticizer, improving the flexibility and durability of various materials, particularly plastics and polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly used in a wide range of industrial applications, including the production of automotive parts, electrical cables, construction materials, and textiles.
Due to concerns about its potential environmental persistence and toxicity, Tris(2-Butoxyethyl) Phosphate (TBEP) has been subject to regulatory scrutiny in some regions.

Regulatory agencies may impose restrictions on its use or require labeling and handling precautions.
Tris(2-Butoxyethyl) Phosphate (TBEP) provides important functional benefits, it is essential to handle it with care.
Occupational exposure should be minimized, and appropriate safety measures should be followed during handling, storage, and disposal.

In response to regulatory concerns and evolving industry standards, researchers and manufacturers are exploring alternative flame retardants and plasticizers that offer comparable performance while minimizing environmental and health risks.
Tris(2-Butoxyethyl) Phosphate (TBEP) is widely used as a flame retardant additive in plastics, textiles, and other materials.

Tris(2-Butoxyethyl) Phosphate (TBEP) works by reducing the flammability of these materials, making them safer in applications where fire hazards are a concern.
In addition to its flame retardant properties, Tris(2-Butoxyethyl) Phosphate (TBEP) also serves as a plasticizer, improving the flexibility and workability of polymers and plastics.

This makes it valuable in manufacturing processes where flexibility is desired.
Tris(2-Butoxyethyl) Phosphate (TBEP) finds use in diverse industrial applications beyond flame retardancy and plasticization.
It is employed in products such as hydraulic fluids, lubricants, coatings, and adhesives.

Like many organophosphate compounds, Tris(2-Butoxyethyl) Phosphate (TBEP) has raised environmental and health concerns.
Its persistence in the environment and potential toxicity to aquatic organisms have prompted regulatory scrutiny and efforts to find safer alternatives.
Regulations governing the use of Tris(2-Butoxyethyl) Phosphate (TBEP) vary by region.

In some jurisdictions, its use may be restricted or subject to specific labeling and handling requirements to minimize environmental and human health risks.
There is ongoing research into alternative flame retardants and plasticizers that offer comparable performance while addressing environmental and health concerns associated with TBEP and similar compounds.
Oral exposure to low-dose Tris(2-Butoxyethyl) Phosphate (TBEP) levels equivalent to tolerable daily intake may exacerbate allergic pulmonary inflammation by promoting a skewed T-helper 2 cell response, upregulation of ERα and dysregulation of both MLN and BM microenvironments.

Uses:
Tris(2-Butoxyethyl) Phosphate (TBEP) is used also in mercerizing liquids, where it improves their wetting properties.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used as a heat-exchange medium.
Release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) can occur from industrial use: as processing aid and of substances in closed systems with minimal release.

Other release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) is likely to occur from: indoor use as processing aid, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use as processing aid and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).
Tris(2-Butoxyethyl) Phosphate (TBEP) can be found in products with material based on: wood (e.g. floors, furniture, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following products: plant protection products, hydraulic fluids, lubricants and greases, metal working fluids, washing & cleaning products and polishes and waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) has an industrial use resulting in manufacture of another substance (use of intermediates).

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following products: polymers and textile treatment products and dyes.
Release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) can occur from industrial use: formulation in materials and formulation of mixtures.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following products: polymers, textile treatment products and dyes and washing & cleaning products.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used for the manufacture of: plastic products and textile, leather or fur.
Release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) can occur from industrial use: in the production of articles, as processing aid and in processing aids at industrial sites.

One of the primary uses of Tris(2-Butoxyethyl) Phosphate (TBEP) is as a flame retardant additive in various materials such as plastics, rubber, textiles, and coatings.
Tris(2-Butoxyethyl) Phosphate (TBEP) reduces the flammability of these materials, making them less likely to catch fire or spread flames.
Tris(2-Butoxyethyl) Phosphate (TBEP) also acts as a plasticizer, improving the flexibility, durability, and workability of plastics and polymers.

Tris(2-Butoxyethyl) Phosphate (TBEP) helps to enhance the processing properties of these materials during manufacturing.
Tris(2-Butoxyethyl) Phosphate (TBEP) is utilized as an additive in lubricants and hydraulic fluids to improve their lubricating properties and thermal stability.
Tris(2-Butoxyethyl) Phosphate (TBEP) helps to reduce friction and wear in mechanical systems.

In some chemical processes, Tris(2-Butoxyethyl) Phosphate (TBEP) serves as a solvent or carrier for other substances.
It can facilitate the dissolution and dispersion of various compounds in solution.
Tris(2-Butoxyethyl) Phosphate (TBEP) is incorporated into coatings, sealants, and adhesives to improve their performance properties.

It can enhance adhesion, flexibility, and resistance to heat and chemicals.
In the textile industry, Tris(2-Butoxyethyl) Phosphate (TBEP) may be used as a finishing agent to impart flame retardant properties to fabrics and garments.
It helps textiles meet flame resistance standards for safety applications.

Tributoxy ethyl phosphate (TBEP) also helps to improve pigment wetting and rheological properties with a minimal effect on reflectance Tributoxy ethyl phosphate (TBEP) is a highly effective "knockdown" defoamer used extensively in paint, textile and paper industries.
Tributoxy ethyl phosphate (TBEP) is also used as a halogen free flame retardant additive in polymer systems. It can be used also in conjunction with other flame retardants.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as an additive flame retardant and plasticizer in plastics and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.
Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly used in the production of polyurethane foam, PVC, and other types of plastics.
Tris(2-Butoxyethyl) Phosphate (TBEP) is effective in reducing the flammability of these materials and improving their fire safety.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a flame retardant for textiles such as curtains, upholstery, and carpets.
It can also be used in the production of flame-resistant clothing for firefighters and other workers in high-risk environments.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the production of electronic components such as circuit boards and cables.

Tris(2-Butoxyethyl) Phosphate (TBEP) helps to reduce the risk of fire and improve the safety of electronic devices.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the production of rubber products such as tires, gaskets, and seals.
It can improve the fire safety of these products and reduce the risk of fire in industrial settings.

Tris(2-Butoxyethyl) Phosphate (TBEP) may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique.
Primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly added to paints, coatings, and varnishes to improve their fire resistance and durability.

It helps these products adhere better to surfaces and provides a protective barrier against fire damage.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as an additive in adhesives and sealants to enhance their bonding strength and flexibility.
It helps prevent the material from becoming brittle over time and improves its resistance to fire.

Tris(2-Butoxyethyl) Phosphate (TBEP) is incorporated into the insulation of electrical wires and cables to reduce the risk of fire propagation in case of a short circuit or overheating.
Tris(2-Butoxyethyl) Phosphate (TBEP) helps maintain the integrity of the insulation and prevents electrical fires.
Tris(2-Butoxyethyl) Phosphate (TBEP) is sometimes used in the production of polyurethane foam, particularly in applications where fire safety is a concern, such as upholstered furniture and mattresses.

It improves the foam's fire resistance without compromising its mechanical properties.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be added to rubber compounds to increase their flame retardancy and flexibility.
It is commonly used in the production of rubber goods such as gaskets, seals, and hoses for various industrial applications.

Tris(2-Butoxyethyl) Phosphate (TBEP) may be included in construction materials such as insulation boards, roofing materials, and sealants to meet fire safety standards and regulations.
It helps prevent the spread of fire in buildings and structures.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the manufacturing of automotive components, including dashboards, interior trims, and upholstery, to improve their fire resistance and durability.
Tris(2-Butoxyethyl) Phosphate (TBEP) helps ensure compliance with automotive safety standards.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in some consumer products such as herbicides and water-thinned paints and tinting bases.

Tris(2-Butoxyethyl) Phosphate (TBEP) may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique.
Primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a solvent and plasticizer for cellulose esters such as nitrocellulose and cellulose acetate.

Tris(2-Butoxyethyl) Phosphate (TBEP) forms stable hydrophobic complexes with some metals; these complexes are soluble in organic solvents as well as supercritical CO2.
The major uses of Tris(2-Butoxyethyl) Phosphate (TBEP) in industry are as a component of aircraft hydraulic fluid, brake fluid, and as a solvent for extraction and purification of rare-earth metals from their ores.
Tris(2-Butoxyethyl) Phosphate (TBEP) finds its use as a solvent in inks, synthetic resins, gums, adhesives (namely for veneer plywood), and herbicide and fungicide concentrates.

As Tris(2-Butoxyethyl) Phosphate (TBEP) has no odour is used as an anti-foaming agent in detergent solutions, and in various emulsions, paints, and adhesives.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also found as a de-foamer in ethylene glycol-borax antifreeze solutions.
In oil-based lubricants addition of Tris(2-Butoxyethyl) Phosphate (TBEP) increases the oil film strength.

Safety Profile:
Tris(2-Butoxyethyl) Phosphate (TBEP) is considered persistent in the environment and may bioaccumulate in aquatic organisms.
It can pose risks to aquatic ecosystems and wildlife, particularly in areas where it is released into waterways or accumulates in sediment.

Despite being used as a flame retardant, Tris(2-Butoxyethyl) Phosphate (TBEP) itself is combustible.
Tris(2-Butoxyethyl) Phosphate (TBEP) may contribute to the spread of fire if not properly contained or managed, posing fire hazards in manufacturing facilities, storage areas, or during transportation.
Tris(2-Butoxyethyl) Phosphate (TBEP) may cause irritation to the skin, eyes, and respiratory tract upon contact or inhalation of its vapors or aerosols.

Prolonged or repeated exposure may lead to more severe health effects, including dermatitis, respiratory irritation, and allergic reactions.
While Tris(2-Butoxyethyl) Phosphate (TBEP)'s acute toxicity is relatively low, chronic exposure to high concentrations may pose health risks.
Animal studies suggest potential adverse effects on the liver, kidneys, and reproductive system, although more research is needed to fully understand its long-term toxicity in humans.

Tris(2-Butoxyethyl) Phosphate (TBEP) is slightly yellow, oily liquid. Insoluble or limited solubility in glycerol, glycols, and certain amines; soluble in most organic liquids.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant. It shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate (TBEP) was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

CAS Number: 78-51-3
Molecular Formula: C18H39O7P
Molecular Weight: 398.47
EINECS Number: 201-122-9

Tris(2-butoxyethyl) phosphate, 78-51-3, TBEP, Tributoxyethyl phosphate, TRI(2-BUTOXYETHYL) PHOSPHATE, Phosflex T-bep, Tris(butoxyethyl) phosphate, tris(2-butoxyethyl)phosphate, KP 140, Kronitex KP-140, Tributyl cellosolve phosphate, Ethanol, 2-butoxy-, phosphate (3:1), Tri(butoxyethyl) phosphate, Phosphoric acid, tributoxyethyl ester, Phosphoric acid, tris(2-butoxyethyl) ester, Tri(2-butoxyethanol)phosphate, NSC 4839, Tris-(2-butoxyethyl)fosfat, Phosphoric Acid Tris(2-butoxyethyl) Ester, 2-Butoxyethanol phosphate, Tris(butoxyethyl)phosphate, Ethanol, 2-butoxy-, 1,1',1''-phosphate, DTXSID5021758, CHEBI:35038, RYA6940G86, tris[2-(butyloxy)ethyl] phosphate, NSC-4839, TBEP;KP 140;Hostaphat B 310, NSC-62228, Phosphoric acid, tri-(2-butoxyethyl) ester, Ethanol, phosphate (3:1), DTXCID201758, WLN: 4O2OPO&O2O4&O2O4, 2-Butoxyethanol, phosphate, CAS-78-51-3, Phosphoric acid, tri(butoxyethyl) ester, TBOEP, CCRIS 5942, Tri(2-butoxyethanol) phosphate, HSDB 2564, 2-Butoxyethanol phosphate (3:1), EINECS 201-122-9, Tris-(2-butoxyethyl)fosfat [Czech], Tris(2-butoxyethyl) phosphate,C18H39O7P,78-51-3, BRN 1716010, tris-2-butoxyethyl phosphate, UNII-RYA6940G86, AI3-04596, Amgard TBEP, MFCD00009456, EC 201-122-9, NCIOpen2_007840, SCHEMBL37268, 4-01-00-02422 (Beilstein Handbook Reference), Tri-(2-Butoxyethyl)phosphate, BIDD:ER0626, Tris(2-butyloxyethyl)phosphate, CHEMBL1534811, NSC4839, NSC62228, 2-Butoxy-ethanol phosphate (3:1), Tox21_201593, Tox21_302891, Tris(2-butoxyethyl) phosphate, 94%, AKOS015839670, NCGC00091600-01, NCGC00091600-02, NCGC00091600-03, NCGC00256553-01, NCGC00259142-01, Tris(2-butoxyethyl)ester phosphoric acid, AS-59809, Phosphoric acid tris(2-n-butoxyethyl)ester, CS-0066127, NS00010389, P0683, Phosphoric acid tris(2-n-butoxyethyl) ester, TRI(2-BUTOXYETHYL) PHOSPHATE [HSDB], F71229, A915093, Tris(2-butoxyethyl) phosphate, analytical standard, W-104277, Q27116378

Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate (TBEP) was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Tris(2-Butoxyethyl) Phosphate (TBEP) is an organophosphate flame retardant and used as a plasticizer in various household products such as plastics, floor polish, varnish, textiles, furniture, and electronic equipment.
Tributoxyethyl Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.

Tris(2-Butoxyethyl) Phosphate (TBEP) is an organophosphate compound used primarily as a flame retardant and plasticizer in various industrial applications.
Its chemical formula is C18H39O7P, and its CAS number is 78-51-3.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly utilized in the production of plastics, polymers, adhesives, and coatings to enhance their flexibility and flame resistance properties.

Additionally, Tris(2-Butoxyethyl) Phosphate (TBEP) finds application as a component in hydraulic fluids, lubricants, and as a solvent in some chemical processes.
Tris(2-Butoxyethyl) Phosphate (TBEP) has been subject to regulatory scrutiny due to its potential environmental and health impacts, and its usage may be subject to restrictions in certain regions.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.

Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.

Tris(2-Butoxyethyl) Phosphate (TBEP), also known as TBEP, is a type of flame retardant that is commonly used in various industries such as plastics, rubber, textiles, and electronics.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a colorless and odorless liquid that is soluble in water, ethanol, and other organic solvents.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a type of organophosphate ester, which means that it is derived from the reaction between phosphoric acid and alcohol.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a versatile flame retardant that has several advantages compared to other types of flame retardants.
One of the main advantages of Tris(2-Butoxyethyl) Phosphate (TBEP) is its high efficiency in reducing the flammability of materials.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a halogen-free flame retardant, which means that it does not contain any bromine or chlorine compounds that are known to be harmful to the environment and human health.

Tris(2-Butoxyethyl) Phosphate (TBEP) works by forming a protective layer on the surface of the material, which prevents the spread of fire.
Tris(2-Butoxyethyl) Phosphate (TBEP) is its compatibility with various types of polymers and resins.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used in combination with other flame retardants to enhance its effectiveness.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also compatible with other additives such as plasticizers and stabilizers, which makes it a versatile ingredient in the production of various types of materials.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also known for its thermal stability and resistance to hydrolysis.
Tris(2-Butoxyethyl) Phosphate (TBEP) can withstand high temperatures without decomposing or releasing toxic gases.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also resistant to moisture and can maintain its effectiveness even in humid environments.
Organophosphates, such as Tris(2-Butoxyethyl) Phosphate (TBEP), are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides.
Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Tris(2-Butoxyethyl) Phosphate (TBEP) may react with oxidizers. .
Tris(2-Butoxyethyl) Phosphate (TBEP) acts as an additive flame retardant and plasticizer in plastics and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate (TBEP) appears as a colorless clear liquid having molecular weight of 398.47.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate (TBEP) has a role as an environmental contaminant and a flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a slightly yellow viscous liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.

Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes Tributoxy ethyl phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a light-colored, high-boiling, non-flammable viscous liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is generally used as a plasticizer in rubber and plastics, and aids in floor polish formation (as well as in other surface coatings),
leveling and improves gloss.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a clear, colorless liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphine oxide and thus very stable in nature.
Tris(2-Butoxyethyl) Phosphate (TBEP) has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, “knockdown” defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used to add flexibility in vinyl resins, other plastics, natural and synthetic rubbers, and floor finishes and waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a flame-retardant plasticizer.
Tris(2-Butoxyethyl) Phosphate (TBEP) is mainly used for flame-retardant and plasticizing of polyurethane resin, cellulose, polyvinyl alcohol, etc.

Tris(2-Butoxyethyl) Phosphate (TBEP) has good low-temperature characteristic.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be obtained by the reaction of the reaction of phosphorus oxychloride and 2-butoxyethanol .
Tris(2-Butoxyethyl) Phosphate (TBEP) is a flammable, hardly inflammable, colorless to yellowish liquid that is sparingly soluble in water.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as an organic flame retardant , as well as in floor care products, as a solvent in resins, as a viscosity modifier in plastisols and as a plasticizer in rubber stoppers.
Tris(2-Butoxyethyl) Phosphate (TBEP)is mainly used as floor polishing agent and processing agent of water-based adhesive, flame retardant and plasticizer of acrylonitrile type rubber, cellulose acetate, epoxy resin, ethyecellulose, polyvinyl acetate, thermoplastic and thermosetting polyurethane.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used as defoamer in coating, detergent and textiles.

Moreover, Tris(2-Butoxyethyl) Phosphate (TBEP) can be also used in nitrocellulose, ethyecellulose and acrylic plastic plasticizer.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a chemical compound commonly used as a flame retardant and plasticizer in various industrial products.
Tris(2-Butoxyethyl) Phosphate (TBEP) is added to materials like plastics, rubber, and textiles to make them less flammable and more flexible.

Tris(2-Butoxyethyl) Phosphate (TBEP) can also be found in hydraulic fluids, lubricants, and as a solvent in certain chemical processes.
While it provides important functional properties to these products, concerns have been raised about its potential environmental and health impacts.
Tris(2-Butoxyethyl) Phosphate (TBEP) has been studied for its persistence in the environment and possible toxicity to aquatic organisms.

As a result, regulations and guidelines regarding its use and disposal may vary depending on the region.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also used as a halogen free flame retardant additive in polymer systems.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used also in conjunction with other flame retardants.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a light-colored, high-boiling, non-flammable viscous liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is generally used as a plasticizer in rubber and plastics, and aids in floor polish formation (as well as in other surface coatings), leveling and improves gloss.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a plasticizer for polyvinyl chloride (PVC), chlorinated rubber and nitriles.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also an alkyl phosphate flame retardant and has good heat stability.

Tris(2-Butoxyethyl) Phosphate (TBEP) can be used in applications needing low temperature flexibility such as a leveling agent for acrylic resin-based polishes.
Tris(2-Butoxyethyl) Phosphate (TBEP) can also be used for emulsions of floor finishes, leveling agent in latex paint, a processing aid for acrylonitrile rubber, antiblock agent for cast polyurethanes.
As a plasticizer, Tris(2-Butoxyethyl) Phosphate (TBEP) incorporates readily and is a non-reactive, medium viscosity liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is high solvency makes it a great product for natural and synthetic resins and compatible with waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used commercially in floor polishes, paper coatings and as an antifoaming agent in ore beneficiations.
Tris(2-Butoxyethyl) Phosphate (TBEP) also finds uses in vinyl plastics.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a clear, colorless liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphine oxide and thus very stable in nature.
Tris(2-Butoxyethyl) Phosphate (TBEP) has many applications including plasticizing agent in acrylic based polishes, defoamer agent in acrylics, “knockdown” defoamer in paint, textile and paper and as a halide free flame retardant in polymer systems.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for polymer dispersions and also improves wetting-levelling properties of drybright emulsions.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate (TBEP) has a role as an environmental contaminant and a flame retardant.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a slightly yellow viscous liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP) is an organic flame retardant.

Tris(2-Butoxyethyl) Phosphate (TBEP) shows PXR agonistic activity.
Tris(2-Butoxyethyl) Phosphate (TBEP) was detected and quantified during the analysis of herring gull eggs by liquid chromatography-electrospray ionization(+)-tandem mass spectrometry.

Melting point: -70°C
Boiling point: 215-228 °C4 mm Hg(lit.)
Density: 1.006 g/mL at 25 °C(lit.)
vapor density: 13.7 (vs air)
vapor pressure: 0.03 mm Hg ( 150 °C)
refractive index: n20/D 1.438(lit.)
Flash point: >230 °F
storage temp.:Store at -20°C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Liquid
color: Clear colorless to very slightly yellow
Water Solubility: Soluble
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey: WTLBZVNBAKMVDP-UHFFFAOYSA-N
LogP: 3.75 at 20℃

Tris(2-Butoxyethyl) Phosphate (TBEP) is widely used as a flame retardant additive in plastics, textiles, and other materials.
Tris(2-Butoxyethyl) Phosphate (TBEP) works by reducing the flammability of these materials, making them safer in applications where fire hazards are a concern.
In addition to its flame retardant properties, Tris(2-Butoxyethyl) Phosphate (TBEP) also serves as a plasticizer, improving the flexibility and workability of polymers and plastics.

This makes it valuable in manufacturing processes where flexibility is desired.
Tris(2-Butoxyethyl) Phosphate (TBEP) finds use in diverse industrial applications beyond flame retardancy and plasticization.
It is employed in products such as hydraulic fluids, lubricants, coatings, and adhesives.

Like many organophosphate compounds, Tris(2-Butoxyethyl) Phosphate (TBEP) has raised environmental and health concerns.
Its persistence in the environment and potential toxicity to aquatic organisms have prompted regulatory scrutiny and efforts to find safer alternatives.
Regulations governing the use of Tris(2-Butoxyethyl) Phosphate (TBEP) vary by region.

In some jurisdictions, its use may be restricted or subject to specific labeling and handling requirements to minimize environmental and human health risks.
There is ongoing research into alternative flame retardants and plasticizers that offer comparable performance while addressing environmental and health concerns associated with TBEP and similar compounds.
Oral exposure to low-dose Tris(2-Butoxyethyl) Phosphate (TBEP) levels equivalent to tolerable daily intake may exacerbate allergic pulmonary inflammation by promoting a skewed T-helper 2 cell response, upregulation of ERα and dysregulation of both MLN and BM microenvironments.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a trialkyl phosphate in which the alkyl group specified is 2-butoxyethyl.
Tris(2-Butoxyethyl) Phosphate (TBEP) has a role as an environmental contaminant and a flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a slightly yellow viscous liquid.

Tris(2-Butoxyethyl) Phosphate (TBEP) is an alkyl phosphate flame retardant and plasticizer, specifically tris(butoxyethyl) phosphate.
Tris(2-Butoxyethyl) Phosphate (TBEP) is recommended fo use as a plasticizer for PVC, chlorinated rubber and for nitrile.
Tris(2-Butoxyethyl) Phosphate (TBEP) is often used as a leveling agent in floor polishes, as a leveling agent in paints, and as an antiblock agent for cast polyurethanes.

Tris(2-Butoxyethyl) Phosphate (TBEP) exhibits low viscosity (12 cps).
Tris(2-Butoxyethyl) Phosphate (TBEP) contains 7.8% phosphorous.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a plasticizer for polyvinyl chloride (PVC), chlorinated rubber and nitriles.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also an alkyl phosphate flame retardant and has good heat stability.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used in applications needing low temperature flexibility such as a leveling agent for acrylic resin-based polishes.
Tris(2-Butoxyethyl) Phosphate (TBEP) can also be used for emulsions of floor finishes, leveling agent in latex paint, a processing aid for acrylonitrile rubber, antiblock agent for cast polyurethanes.

As a plasticizer, Tris(2-Butoxyethyl) Phosphate (TBEP), incorporates readily and is a non-reactive, medium viscosity liquid.
Tris(2-Butoxyethyl) Phosphate (TBEP)s high solvency makes it a great product for natural and synthetic resins and compatible with waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used commercially in floor polishes, paper coatings and as an antifoaming agent in ore beneficiations.

Tris(2-Butoxyethyl) Phosphate (TBEP) also finds uses in vinyl plastics.
Tris(2-Butoxyethyl) Phosphate (TBEP) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used by consumers, in articles, by professional workers (widespread uses), in formulation or repacking and at industrial sites.

Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.
Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.

The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.
Tris(2-Butoxyethyl) Phosphate (TBEP) is widely used in household materials such as plasticizer, floor polish and flame retardant in plastic resins and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate (TBEP)-based is a plasticizer and defoamer.
Tris(2-Butoxyethyl) Phosphate (TBEP) also acts as a leveling agent for acrylic and styrenic floor polishes and coalescent additive for emulsion polymers.

Tris(2-Butoxyethyl) Phosphate (TBEP) is valued for its effectiveness as a flame retardant.
Tris(2-Butoxyethyl) Phosphate (TBEP) works by reducing the flammability of materials, thereby slowing down or preventing the spread of fire.
In addition to its flame retardant properties, Tris(2-Butoxyethyl) Phosphate (TBEP) acts as a plasticizer, improving the flexibility and durability of various materials, particularly plastics and polymers.

Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly used in a wide range of industrial applications, including the production of automotive parts, electrical cables, construction materials, and textiles.
Due to concerns about its potential environmental persistence and toxicity, Tris(2-Butoxyethyl) Phosphate (TBEP) has been subject to regulatory scrutiny in some regions.
Regulatory agencies may impose restrictions on its use or require labeling and handling precautions.

Tris(2-Butoxyethyl) Phosphate (TBEP) provides important functional benefits, it is essential to handle it with care.
Occupational exposure should be minimized, and appropriate safety measures should be followed during handling, storage, and disposal.
In response to regulatory concerns and evolving industry standards, researchers and manufacturers are exploring alternative flame retardants and plasticizers that offer comparable performance while minimizing environmental and health risks.

Uses Of Tris(2-Butoxyethyl) Phosphate (TBEP):
Tris(2-Butoxyethyl) Phosphate (TBEP) may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique.
Primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a solvent and plasticizer for cellulose esters such as nitrocellulose and cellulose acetate.

Tris(2-Butoxyethyl) Phosphate (TBEP) forms stable hydrophobic complexes with some metals; these complexes are soluble in organic solvents as well as supercritical CO2.
The major uses of Tris(2-Butoxyethyl) Phosphate (TBEP) in industry are as a component of aircraft hydraulic fluid, brake fluid, and as a solvent for extraction and purification of rare-earth metals from their ores.
Tris(2-Butoxyethyl) Phosphate (TBEP) finds its use as a solvent in inks, synthetic resins, gums, adhesives (namely for veneer plywood), and herbicide and fungicide concentrates.

As Tris(2-Butoxyethyl) Phosphate (TBEP) has no odour is used as an anti-foaming agent in detergent solutions, and in various emulsions, paints, and adhesives.
Tris(2-Butoxyethyl) Phosphate (TBEP) is also found as a de-foamer in ethylene glycol-borax antifreeze solutions.
In oil-based lubricants addition of Tris(2-Butoxyethyl) Phosphate (TBEP) increases the oil film strength.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used also in mercerizing liquids, where it improves their wetting properties.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be used as a heat-exchange medium.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in some consumer products such as herbicides and water-thinned paints and tinting bases.

Release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) can occur from industrial use: as processing aid and of substances in closed systems with minimal release.
Other release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) is likely to occur from: indoor use as processing aid, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use as processing aid and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

Tris(2-Butoxyethyl) Phosphate (TBEP) can be found in products with material based on: wood (e.g. floors, furniture, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper).
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following products: plant protection products, hydraulic fluids, lubricants and greases, metal working fluids, washing & cleaning products and polishes and waxes.
Tris(2-Butoxyethyl) Phosphate (TBEP) has an industrial use resulting in manufacture of another substance (use of intermediates).

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following products: polymers and textile treatment products and dyes.
Release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) can occur from industrial use: formulation in materials and formulation of mixtures.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the following products: polymers, textile treatment products and dyes and washing & cleaning products.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used for the manufacture of: plastic products and textile, leather or fur.
Release to the environment of Tris(2-Butoxyethyl) Phosphate (TBEP) can occur from industrial use: in the production of articles, as processing aid and in processing aids at industrial sites.

One of the primary uses of Tris(2-Butoxyethyl) Phosphate (TBEP) is as a flame retardant additive in various materials such as plastics, rubber, textiles, and coatings.
Tris(2-Butoxyethyl) Phosphate (TBEP) reduces the flammability of these materials, making them less likely to catch fire or spread flames.
Tris(2-Butoxyethyl) Phosphate (TBEP) also acts as a plasticizer, improving the flexibility, durability, and workability of plastics and polymers.

Tris(2-Butoxyethyl) Phosphate (TBEP) helps to enhance the processing properties of these materials during manufacturing.
Tris(2-Butoxyethyl) Phosphate (TBEP) is utilized as an additive in lubricants and hydraulic fluids to improve their lubricating properties and thermal stability.
Tris(2-Butoxyethyl) Phosphate (TBEP) helps to reduce friction and wear in mechanical systems.

In some chemical processes, Tris(2-Butoxyethyl) Phosphate (TBEP) serves as a solvent or carrier for other substances.
It can facilitate the dissolution and dispersion of various compounds in solution.
Tris(2-Butoxyethyl) Phosphate (TBEP) is incorporated into coatings, sealants, and adhesives to improve their performance properties.

It can enhance adhesion, flexibility, and resistance to heat and chemicals.
In the textile industry, Tris(2-Butoxyethyl) Phosphate (TBEP) may be used as a finishing agent to impart flame retardant properties to fabrics and garments.
It helps textiles meet flame resistance standards for safety applications.

Tributoxy ethyl phosphate (TBEP) also helps to improve pigment wetting and rheological properties with a minimal effect on reflectance Tributoxy ethyl phosphate (TBEP) is a highly effective "knockdown" defoamer used extensively in paint, textile and paper industries.
Tributoxy ethyl phosphate (TBEP) is also used as a halogen free flame retardant additive in polymer systems. It can be used also in conjunction with other flame retardants.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as an additive flame retardant and plasticizer in plastics and synthetic rubbers.
Tris(2-Butoxyethyl) Phosphate (TBEP) is a phosphate ester that, thanks to its structure, can be used in many applications including plasticisation, solvation, flame retardancy and defoaming.
Tris(2-Butoxyethyl) Phosphate (TBEP) is in fact a multifunctional additive that may be used to modify the properties of many polymer systems and is a particularly good levelling aid and coalescent additive for emulsion polymers.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in a mixed solvent/aqueous system as a defoamer during production and as a secondary plasticiser in many polymers.
The above properties in combination with inherent flame retardancy makes Tris(2-Butoxyethyl) Phosphate (TBEP) a real multifunctional additive essential to many polymer formulations.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a plasticizer for PVC, chlorinated rubber, and nitriles due to its flame retardant nature and good low temperature flexibility.

Tris(2-Butoxyethyl) Phosphate (TBEP) is also used for emulsions of floor polishes, as leveling agent in latex paints and waxes, a processing aid for acrylonitrile rubber, and an antiblock agent for cast polyurethanes.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly used in the production of polyurethane foam, PVC, and other types of plastics.
Tris(2-Butoxyethyl) Phosphate (TBEP) is effective in reducing the flammability of these materials and improving their fire safety.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used as a flame retardant for textiles such as curtains, upholstery, and carpets.
It can also be used in the production of flame-resistant clothing for firefighters and other workers in high-risk environments.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the production of electronic components such as circuit boards and cables.

Tris(2-Butoxyethyl) Phosphate (TBEP) helps to reduce the risk of fire and improve the safety of electronic devices.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the production of rubber products such as tires, gaskets, and seals.
It can improve the fire safety of these products and reduce the risk of fire in industrial settings.

Tris(2-Butoxyethyl) Phosphate (TBEP) may be used as an analytical reference standard for the quantification of the analyte in herring gull eggs, house dust, and urine samples using liquid chromatography technique.
Primary plasticizer for most resins and elastomers, floor finishes and waxes, flame-retarding agent.
Tris(2-Butoxyethyl) Phosphate (TBEP) is commonly added to paints, coatings, and varnishes to improve their fire resistance and durability.

It helps these products adhere better to surfaces and provides a protective barrier against fire damage.
Tris(2-Butoxyethyl) Phosphate (TBEP) is used as an additive in adhesives and sealants to enhance their bonding strength and flexibility.
It helps prevent the material from becoming brittle over time and improves its resistance to fire.

Tris(2-Butoxyethyl) Phosphate (TBEP) is incorporated into the insulation of electrical wires and cables to reduce the risk of fire propagation in case of a short circuit or overheating.
Tris(2-Butoxyethyl) Phosphate (TBEP) helps maintain the integrity of the insulation and prevents electrical fires.
Tris(2-Butoxyethyl) Phosphate (TBEP) is sometimes used in the production of polyurethane foam, particularly in applications where fire safety is a concern, such as upholstered furniture and mattresses.

It improves the foam's fire resistance without compromising its mechanical properties.
Tris(2-Butoxyethyl) Phosphate (TBEP) can be added to rubber compounds to increase their flame retardancy and flexibility.
It is commonly used in the production of rubber goods such as gaskets, seals, and hoses for various industrial applications.

Tris(2-Butoxyethyl) Phosphate (TBEP) may be included in construction materials such as insulation boards, roofing materials, and sealants to meet fire safety standards and regulations.
It helps prevent the spread of fire in buildings and structures.

Tris(2-Butoxyethyl) Phosphate (TBEP) is used in the manufacturing of automotive components, including dashboards, interior trims, and upholstery, to improve their fire resistance and durability.
Tris(2-Butoxyethyl) Phosphate (TBEP) helps ensure compliance with automotive safety standards.

Safety Profile:
Tris(2-Butoxyethyl) Phosphate (TBEP) may cause irritation to the skin, eyes, and respiratory tract upon contact or inhalation of its vapors or aerosols.
Prolonged or repeated exposure may lead to more severe health effects, including dermatitis, respiratory irritation, and allergic reactions.
While Tris(2-Butoxyethyl) Phosphate (TBEP)'s acute toxicity is relatively low, chronic exposure to high concentrations may pose health risks.

Animal studies suggest potential adverse effects on the liver, kidneys, and reproductive system, although more research is needed to fully understand its long-term toxicity in humans.
Tris(2-Butoxyethyl) Phosphate (TBEP) is considered persistent in the environment and may bioaccumulate in aquatic organisms.
It can pose risks to aquatic ecosystems and wildlife, particularly in areas where it is released into waterways or accumulates in sediment.

Despite being used as a flame retardant, Tris(2-Butoxyethyl) Phosphate (TBEP) itself is combustible.
Tris(2-Butoxyethyl) Phosphate (TBEP) may contribute to the spread of fire if not properly contained or managed, posing fire hazards in manufacturing facilities, storage areas, or during transportation.

Tris(2-chloroethyl) phosphate (TCEP) has excellent flame retardance, cold resistance, and UV resistance.
Tris(2-chloroethyl) phosphate (TCEP) is an odorless clear liquid.


CAS Number: 115-96-8
EC Number: 204-118-5
MDL number: MFCD00000967
Chemical formula: C6H12Cl3O4P
Molecular Formula: C6H12Cl3O4P / (ClCH2CH2O)3PO



SYNONYMS:
Tris(2-chloroethyl) phosphate, 115-96-8, Tri(beta-chloroethyl) phosphate, Tris(2-chloroethyl) orthophosphate, TRIS(2-CHLOROETHYL) PHOSPHATE, Tris(2-chloroethyl)phosphate, Celluflex, Fyrol CEF, Disflamoll TCA, Celluflex CEF, Tris(chloroethyl) phosphate, Niax 3CF, Tris(chloroethyl)phosphate, Trichlorethyl phosphate, 2-Chloroethanol phosphate, TRI(2-CHLOROETHYL) PHOSPHATE, Niax Flame Retardant 3CF, Ethanol, 2-chloro-, phosphate (3:1), Ethanol, 2-chloro-, 1,1',1''-phosphate, Tris(beta-chloroethyl) phosphate, NCI-C60128, Tris-(2-chlorethyl)fosfat, NSC 3213, DTXSID5021411, Phosphoric Acid Tris(2-chloroethyl) Ester, Phosphoric acid, tris(2-chloroethyl)ester, Tri(.beta.-chloroethyl) phosphate, Phosphoric acid, tris(2-chloroethyl) ester, 68411-66-5, CHEBI:35037, 32IVO568B0, Tris(.beta.-chloroethyl) phosphate, NSC-3213, 29716-44-7, Genomoll P, 3CF, Antiblaze 100, DTXCID601411, Tris(2-chloroethyl) phosphate 10 microg/mL in Cyclohexane, Fyrol CF, Tri(2-chloroethyl)phosphate, C6H12Cl3O4P, CAS-115-96-8, Tri-beta-chloroethyl phosphate, CCRIS 1302, HSDB 2577, Tris-(2-chlorethyl)fosfat [Czech], EINECS 204-118-5, Tris-(2-chloroethyl)fosfat [Czech], Tris-(2-chloroethyl)fosfat, BRN 1710938, UNII-32IVO568B0, AI3-15023, Tris(|A-chloroethyl) phosphate, 2-Chloro-ethanol phosphate (3:1), EINECS 249-806-6, EC 204-118-5, SCHEMBL26896, Tris(-chloroethyl) phosphate, 4-01-00-01379 (Beilstein Handbook Reference), MLS001056210, BIDD, , tris(2-chloroethyl)-phosphate, tri-(2-chloroethyl) phosphate, CHEMBL1413786, Tri-.beta.-chloroethyl phosphate, WLN: G2OPO & O2GO2G, NSC3213, EINECS 270-139-1, Tox21_201254, Tox21_300074, MFCD00000967, Tris(2-chloroethyl) phosphate, 97%, AKOS009029110, NCGC00091566-01, NCGC00091566-02, NCGC00091566-03, NCGC00254139-01, NCGC00258806-01, Phosphoric acid, tri-2-chloroethyl ester, SMR001216601, CS-0030742, NS00010387, P0268, T3447, EN300-19161, TRIS(2-CHLOROETHYL) PHOSPHATE [HSDB], TRIS(2-CHLOROETHYL) PHOSPHATE [IARC], Tris(2-chloroethyl) phosphate, analytical standard, J-003352, Q1670500, Tris(2-chloroethyl) phosphate, certified reference material, TraceCERT(R), InChI=1/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H, Phosphoric acid tris(2-chloroethyl) ester, Phosphoric acid, tris(2-chloroethyl)ester, Tri(2-chloroethyl) phosphate, Tris(2-chloroethyl) orthophosphate, Tris(2-chloroethyl)phosphic acid, Tris(beta-chloroethyl) phosphate, Tris(chloroethyl)phosphate, Tris(β-chloroethyl) phosphate; TCEP; tris(1-chloroethyl) phosphate, TCEP, TRIS(2-CHLOROETHYL)PHOSPHATE, tris(chloroethyl)phosphate, Tris(chloroethyl) phosphate, TRIS(2-CHLOROETHYL)PHOSPHATE 97%, Phosphorsuretris-(2-chlorethyl)-ester, 3CF, niax3cf, Fyrol CF, fyrolcef, 2-Chloroethanol phosphate, Tris(β-chloroethyl) phosphate, Tri(2-chloroethyl) phosphate, Tris(2-chloroethyl) orthophosphate, TCEP, Ethanol, 2-chloro-, phosphate (3:1), Celluflex CEF, Disflamoll TCA, Fyrol CEF, Niax Flame Retardant 3CF, Niax 3CF, Tri(β-chloroethyl) phosphate, Trichloroethyl phosphate, Tris(β-chloroethyl) phosphate, Tris(chloroethyl) phosphate, Tris(2-chloroethyl) orthophosphate, Tris(2-chloroethyl) phosphate, 3CF, Celluflex, Phosphoric acid, tris(2-chloroethyl) ester, Trichlorethyl phosphate, 2-Chloroethanol phosphate, NCI-C60128, Tris-(2-chlorethyl)fosfat, 2-Chloro-ethanol phosphate (3:1), Fyrol CF, Genomoll P, TCEP, Phosphoric acid, tri-2-chloroethyl ester, NSC 3213



Tris(2-chloroethyl) phosphate (TCEP) is a clear transparent liquid with a very slight odor. Insoluble in water.
Tris(2-chloroethyl) phosphate (TCEP) has excellent flame retardance, cold resistance, and UV resistance.
Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates.


Tris(2-chloroethyl) phosphate (TCEP) belongs to the class of organic compounds known as trialkyl phosphates.
These are organic compounds containing a phosphate group that is linked to exactly three alkyl chains.
Tris(2-chloroethyl) phosphate (TCEP) has excellent flame retartance, cold resistance and UV resistance.


Tris(2-chloroethyl) phosphate (TCEP) is an organophosphate triester compound used in solid-phase microextractions
Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates.


Tris(2-chloroethyl) phosphate (TCEP) is registered under the REACH Regulation but is not currently being manufactured in and / or imported to the European Economic Area.
Tris(2-chloroethyl) phosphate (TCEP) is an odorless clear liquid.


Tris(2-chloroethyl) phosphate (TCEP) is a trialkyl phosphate that is the tris(2-chloroethyl) ester of phosphoric acid.
Tris(2-chloroethyl) phosphate (TCEP) is a trialkyl phosphate and an organochlorine compound.
Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates.


Tris(2-chloroethyl) phosphate (TCEP) has been added to polyurethane foams and plastics in:
*Certain children’s products with foam padding, such as some crib bumpers, sleep mats, changing table pads, and portable mattresses.
*Some motor vehicles, furniture, building insulation, back-coatings of carpets and upholstery, and electronic and electrical devices.


Ethanol, 2-chloro-, phosphate (3:1), also known as Tris(2-chloroethyl) phosphate (TCEP), is an industrial chemical.
Tris(2-chloroethyl) phosphate (TCEP) is a colorless or light yellow oily liquid with a light cream odor.
Tris(2-chloroethyl) phosphate (TCEP) is slightly soluble in water, easily soluble in alcohols, ketones, aromatic hydrocarbon, but insoluble in an aliphatic hydrocarbon.


Tris(2-chloroethyl) phosphate (TCEP) is also called petroleum additive and an extractant of rare-earth elements.
Tris(2-chloroethyl) phosphate (TCEP) is a clear, transparent liquid. Slightly water soluble.
Tris(2-chloroethyl) phosphate (TCEP) is a human urinary organophosphate flame retardant metabolite.


Tris(2-chloroethyl) phosphate (TCEP) is a trialkyl phosphate that is the tris(2-chloroethyl) ester of phosphoric acid.
Tris(2-chloroethyl) phosphate (TCEP) is a odorless clear liquid. Neutral pH.
Tris(2-chloroethyl) phosphate (TCEP) is incompatible with strong oxidizing agents and strong bases.


Tris(2-chloroethyl) phosphate (TCEP) is a colorless or light yellow oily transparent liquid with light cream taste.
Tris(2-chloroethyl) phosphate (TCEP) is miscible with ordinary organic solvents, but insoluble in aliphatic hydrocarbons, and has good hydrolysis stability.
Tris(2-chloroethyl) phosphate (TCEP) is a flame retardant.


Tris(2-chloroethyl) phosphate (TCEP) is a halogenated phosphate ester flame retardant and plasticizer, commonly used in flame retardant paints with nitrocellulose and cellulose acetate as substrates, unsaturated polyesters, polyurethanes, acrylates, phenolic resins, etc.
Tris(2-chloroethyl) phosphate (TCEP) can be used as a soft plasticized flame retardant for PVC.



USES and APPLICATIONS of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
Tris(2-chloroethyl) phosphate (TCEP) is widely used in chemical and blended fabrics and cellulose acetate as fire retardant.
Tris(2-chloroethyl) phosphate (TCEP) is an organophosphate triester compound used in solid-phase microextractions
Tris(2-chloroethyl) phosphate (TCEP) has been widely used as a plasticizer and flame retardant.


Tris(2-chloroethyl) phosphate (TCEP) as a potential carcinogen is often detected in the occupational and nature environments
Tris(2-chloroethyl) phosphate (TCEP) is used as additive type halogenated phosphate ester flame retardant and plasticizer, commonly used in flame retardant paints with nitrocellulose and cellulose acetate as substrates, unsaturated polyesters, polyurethanes, acrylates, phenolic resins, etc.


Tris(2-chloroethyl) phosphate (TCEP) can be used as a soft plasticized flame retardant for PVC.
Tris(2-chloroethyl) phosphate (TCEP) is widely used in cellulose acetate, polyvinyl chloride, polyurethane, polyvinyl acetate, phenolic resins, and other synthetic materials.


In addition to its flame retardant properties, Tris(2-chloroethyl) phosphate (TCEP) also can improve the material's water resistance, cold resistance, antistatic property and softness.
Tris(2-chloroethyl) phosphate (TCEP) is widely used in chemical and blended fabrics and cellulose acetate is a fire retardant.


Tris(2-chloroethyl) phosphate (TCEP) is used in articles, by professional workers (widespread uses) and at industrial sites.
Other release to the environment of Tris(2-chloroethyl) phosphate (TCEP) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Tris(2-chloroethyl) phosphate (TCEP) can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material) and metal (e.g. cutlery, pots, toys, jewellery).
Tris(2-chloroethyl) phosphate (TCEP) is used in the following products: coating products.


Tris(2-chloroethyl) phosphate (TCEP) is used in the following areas: offshore mining and building & construction work.
Other release to the environment of Tris(2-chloroethyl) phosphate (TCEP) is likely to occur from: outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).


Tris(2-chloroethyl) phosphate (TCEP) is used in the following products: coating products.
Tris(2-chloroethyl) phosphate (TCEP) is used in the following areas: offshore mining and building & construction work.
Release to the environment of Tris(2-chloroethyl) phosphate (TCEP) can occur from industrial use: in the production of articles.


Tris(2-chloroethyl) phosphate (TCEP) is a chemical compound used as a flame retardant, plasticizer, and viscosity regulator in various types of polymers including polyurethanes, polyester resins, and polyacrylates.
Tris(2-chloroethyl) phosphate (TCEP) is the excellent flame retardant of synthetic materials, it can be widely used in polyurethane foam, polyolefin resin, polyester resin, phenolic resin and cellulose acetate, which can make the product with self extinguishing.


Tris(2-chloroethyl) phosphate (TCEP) also can be used as the main flame retardant material for the production of flame retardant cable, tarpaulin, flame retardant rubber conveying belt and flame sponge composite.
Tris(2-chloroethyl) phosphate (TCEP) is mainly used in flame retardant of PVC, polyvinyl acetate, phenolic resin, polyurethane, cellulose acetate, cellulose nitrate, ethyecellulos.


Moreover, Tris(2-chloroethyl) phosphate (TCEP) can also be used in processing modifier of metal extractant, lubricating oil, gasoline additive and polyimide.
Tris(2-chloroethyl) phosphate (TCEP) is used as a plasticizer and viscosity regulator with flame retardant properties in polyurethanes, polyester resins, polyacrylates, and other polymers.


These polymers may be used in furniture, building (for example, roofing insulation) and textile industries (for example, back-coatings for carpets and upholstery).
Tris(2-chloroethyl) phosphate (TCEP) may also be used in electronic products and in the manufacture of cars.


Tris(2-chloroethyl) phosphate (TCEP) is not manufactured, but is imported into Canada.
Due to the good plasticization, Tris(2-chloroethyl) phosphate (TCEP) is widely used in cellulose acetate, polyvinyl acetate, nitrocellulose lacquer, ethyl cellulose, PVC, polyurethane, and phenolic resin, which all have a self-extinguish ability.
With the addition of Tris(2-chloroethyl) phosphate (TCEP), their physical properties are improved and tactilities feel soft.


Moreover, Tris(2-chloroethyl) phosphate (TCEP) is a main flame-retardant material to produce polyurethane for flame-retardant cables, anti-corrosion tarpaulin, and flame-retardant rubber converter belts.
Tris(2-chloroethyl) phosphate (TCEP) is mainly used for flame-retardant polyurethane foam and flame-retardant plasticization of PVC.


Tris(2-chloroethyl) phosphate (TCEP) is widely used in chemical fiber fabrics and cellulose acetate as flame retardants.
In addition to self-extinguishing, Tris(2-chloroethyl) phosphate (TCEP) can also improve water resistance, cold resistance and antistatic properties.
The general dosage of Tris(2-chloroethyl) phosphate (TCEP) is 5-10 parts.


Flame retardants, Tris(2-chloroethyl) phosphate (TCEP) is commonly used in lithium batteries.
Tris(2-chloroethyl) phosphate (TCEP) can also be used as metal extractant, lubricant and gasoline additives, and polyimide processing modifier.
Tris(2-chloroethyl) phosphate (TCEP) is widely used in polyvinyl chloride, polyurethane soft and rigid foam, cellulose acetate, nitrocellulose paint, ethyl cellulose paint and flame retardant rubber conveyor belt.


The obtained products have self-extinguishing properties and can improve water resistance.
Weather resistance, cold resistance, antistatic property, soft hand feel, the general addition amount is 5-10 parts, and the oxygen index (OI) of polyurethane rigid foam can reach 26.


In addition, Tris(2-chloroethyl) phosphate (TCEP) can also be used as extreme pressure additive for lubricating oil, gasoline additive and thermal coolant of metal magnesium, etc.
Tris(2-chloroethyl) phosphate (TCEP) is an excellent flame retardant of synthetic materials, and has a good plasticizer effect.


Tris(2-chloroethyl) phosphate (TCEP) is widely used in cellulose acetate, nitrocellulose varnish, ethyl cellulose, polyvinyl chloride, polyvinyl acetate, polyurethane, phenolic resin.
In addition to self extinguishing, Tris(2-chloroethyl) phosphate (TCEP) can also improve the physical properties of the product.


Tris(2-chloroethyl) phosphate (TCEP) feels soft, and can also be used as a petroleum additive and an extractant of olefinic elements, Tris(2-chloroethyl) phosphate (TCEP) is also the main flame retardant material for manufacturing flame retardant cable three proof tarpaulin and flame retardant rubber conveyor belt, with the general addition amount of 10-15%.


Tris(2-chloroethyl) phosphate (TCEP) is used as the flame retardant agent in polyurethane, plastics, polyester, textiles.
Tris(2-chloroethyl) phosphate (TCEP) has excellent flame retarding properties because of the phosphorus and chlorine content.
Tris(2-chloroethyl) phosphate (TCEP) was used in dynamic air sampling of airborne organophosphate triesters using a solid-phase microextraction device.



CHARACTERISTICS OF TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
Tris(2-chloroethyl) phosphate (TCEP) is colorless or light yellow oily liquid, with sour cream smell, soluble with organic solvents such as alcohols, ketones, esters, aromatic hydrocarbons, chloroform and catalyst, insoluble with aliphatic hydroxyl, almost insoluble in water. It have good hydrolytic stability, it will decompose a little in sodium hydroxide solution.
Tris(2-chloroethyl) phosphate (TCEP) has excellent UV stability and low temperature performance.



PROPERTIES OF TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
Tris(2-chloroethyl) phosphate (TCEP) is an organophosphorus flame retardant halogen compound.
Tris(2-chloroethyl) phosphate (TCEP) is not soluble in water, can dissolve in ethanol, acetone, esters, aromatics, chloroform and other organic solvents.



HOW DOES EXPOSURE TO TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP) OCCUR?
Tris(2-chloroethyl) phosphate (TCEP) can be gradually released from products treated with TCEP into indoor environments, including houses, schools, day care centers, offices, and cars.
Once Tris(2-chloroethyl) phosphate (TCEP) is released from products, it is present on floors, furniture, and other surfaces, and in air and dust.
During pregnancy, TCEP can pass from mother to baby.



COMPOUND TYPE OF TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
*Ester
*Industrial/Workplace Toxin
*Organic Compound
*Organochloride
*Plasticizer
*Synthetic Compound



ALTERNATIVE PARENTS OF TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
*Organooxygen compounds
*Organochlorides
*Organic oxides
*Hydrocarbon derivatives
*Alkyl chlorides



SUBSTITUENTS OF TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
*Trialkyl phosphate
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Organochloride
*Organohalogen compound
*Alkyl halide
*Alkyl chloride
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
Chemical Formula: C₆H₁₂Cl₃O₄P
Molar Mass: 285.48 g/mol
Molecular Weight: 285.5 g/mol
Exact Mass: 283.953879 g/mol
Monoisotopic Mass: 283.953879 g/mol
Physical Properties
Density: 1.39 g/mL
Boiling Point: 192 °C (378 °F; 465 K) at 10 mmHg
Topological Polar Surface Area (PSA): 44.8 Ų
Chemical Properties
XLogP3-AA: 1.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4

Rotatable Bond Count: 9
Heavy Atom Count: 14
Complexity: 152
Covalently-Bonded Unit Count: 1
Stereochemistry
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Isotope Atom Count: 0
Physical State: Clear liquid

Color: Colorless
Odor: No data available
Melting Point/Freezing Point: Approximately -60 °C (ASTM D 97-66)
Initial Boiling Point and Boiling Range: 192 °C at 13 hPa
Flash Point: 232 °C (closed cup)
Autoignition Temperature: No data available
Decomposition Temperature: No data available
pH: No data available
Viscosity: 38-42 mPa·s (dynamic) at 25 °C
Water Solubility: 7.943 g/L at 20 °C (soluble)
Partition Coefficient (log Pow): 1.7 at 20 °C
Vapor Pressure: < 13 hPa at 25 °C
Density: 1.39 g/cm³ at 25 °C
Refractive Index (nD25): 1.470-1.479

Chemical Properties
Acidity (mg KOH/g): ≤0.1
Moisture Content: ≤0.1%
Phosphorus Content: 10.65-10.9%
Chlorine Content: 36.5-37.5%
Color (APHA): ≤50
Additional Information
Flammability (Solid, Gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available

Explosive Properties: No data available
Oxidizing Properties: None
Other Safety Information: No data available
Appearance: Colorless to yellowish transparent liquid
Specific Gravity (20°C): 1.41-1.43
Melting Point: -51 °C
Boiling Point: 192 °C/10 mmHg (lit.)
Density: 1.39 g/mL at 25 °C (lit.)
Vapor Pressure: Refractive Index (nD20): 1.472 (lit.)
Flash Point: 450 °F (approximately 232 °C)

Storage Temperature: 2-8 °C
Form: Liquid
Color: Clear colorless
Viscosity (25°C): 38-42 mPa·s (dynamic)
Water Content: ≤0.3%
Chemical Properties
Molecular Formula: C₆H₁₂Cl₃O₄P
Molecular Weight: 285.49 g/mol
Acid Content: ≤0.1 mg KOH/g
Water Solubility: 7.82 g/L at 20 °C
LogP: 1.7 at 20 °C
Stability: Stable. Incompatible with strong bases, strong oxidizing agents.
Color Value: 50 max

Safety and Regulatory Information
InChIKey: HQUQLFOMPYWACS-UHFFFAOYSA-N
FDA 21 CFR: 175.105
CAS Number: 115-96-8
FDA UNII: 32IVO568B0
Proposition 65 List: Tris(2-chloroethyl) Phosphate
IARC Classification: 3 (Vol. 48, 71) 1999
NIST Chemistry Reference: Phosphoric acid, tri-2-chloroethyl ester (115-96-8)
EPA Substance Registry System: Tris(2-chloroethyl) phosphate (115-96-8)
EWG's Food Scores: 1
Additional Information

Acidity (mg KOH/g): 0.2 max
Flash Point (°C): 220 min
Phosphorus Content: 10.7-10.8%
Specific Gravity (20°C): 1.420-1.440
Appearance: Colorless or light yellow oily transparent liquid
Physical State: Liquid
Density: 1.39 g/mL at 25 °C (lit.)
Refractive Index (nD20): 1.4731
Boiling Point: 194 °C
Flash Point: 225 °C
Freezing Point: -64 °C
Decomposition Temperature: 240-280 °C
Viscosity: 38-47 cP (20 °C)

Storage: Store at room temperature
Chemical Properties
Chemical Formula: C₆H₁₂Cl₃O₄P
Average Molecular Mass: 285.490 g/mol
Monoisotopic Mass: 283.954 g/mol
Phosphorus Content: 10.8%
Chlorine Content: 37.3%
SMILES: ClCCOP(=O)(OCCCl)OCCCl
IUPAC Name: Tris(2-chloroethyl) phosphate
Traditional Name: Tris(2-chloroethyl) phosphate
InChI Identifier: InChI=1S/C6H12Cl3O4P/c7-1-4-11-14(10,12-5-2-8)13-6-3-9/h1-6H2
InChI Key: HQUQLFOMPYWACS-UHFFFAOYSA-N



FIRST AID MEASURES of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Tightly closed.
Keep in a well-ventilated place. Keep locked up or in an area accessible only
to qualified or authorized persons.



STABILITY and REACTIVITY of TRIS(2-CHLOROETHYL) PHOSPHATE (TCEP):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available

Trioctyl phosphate; Triethylhexyl phosphate; Phosphoric acid, tris(2-ethylhexyl) ester; TOF; 2-Ethylhexanol, phosphate Triester; 2-Ethyl-1-hexanol phosphate; Tris(2-ethylhexyl)phosphate; Tris(2-ethylhexyl)phosphat (German); Fosfato de tris(2-etilhexilo) (Spanish); Phosphate de tris(2-éthylhexyle) (French); cas no: 78-42-2

Clear colorless viscous liquid.
Tris(2-chloropropyl) phosphate ( TCPP), mixture of isomers is suitable for use in environmental and food residue analysis.
Tris(2-chloropropyl) phosphate ( TCPP) is a mixture of isomers, composition may vary, typical composition: main isomer tris(1-chloro-2-propyl) phosphate 66%, minor components: bis(1-chloro-2-propyl) (2-chloropropyl) phosphate and (1-chloro-2-propyl) bis(2-chloropropyl) phosphate.

CAS: 13674-84-5
MF: C9H18Cl3O4P
MW: 327.57
EINECS: 237-158-7

Synonyms
Phosphoric acid tris(2-chloro-1-methylethyl) ester;TRIS(1-CHLORO-2-PROPYL) PHOSPHATE;TRIS(1-CHLOROPROPYL)PHOSPHATE;TRIS(2-CHLORO-1-METHYLETHYL) PHOSPHATE;TRIS(CHLOROISOPROPYL)PHOSPHATE;TRIS(MONOCHLOROPROPYL) PHOSPHATE;tris(2-chloroisopropyl)phosphate;TcppTris(1-Chloro-2-Propyl)Phosphate];13674-84-5;Tris(1-chloro-2-propyl) phosphate;tris(1-chloropropan-2-yl) phosphate;Amgard TMCP;TRIS(2-CHLOROISOPROPYL)PHOSPHATE;Tris(2-chloro-1-methylethyl) phosphate;Hostaflam OP 820;Tris(1-chloro-2-propyl)phosphate;2-Propanol, 1-chloro-, phosphate (3:1);TRIS(2-CHLOROISOPROPYL) PHOSPHATE;2-Propanol, 1-chloro-, 2,2',2''-phosphate;Tris(1-chloro-2-propyl) phosphate, tech grade;CRT22GFY70;Phosphoric acid, tris(2-chloro-1-methylethyl) ester;DTXSID5026259;Tris(1-chloro-2-propanyl) phosphate;DTXCID106259;CCRIS 6111;Tri-(2-chloroisopropyl)phosphate;Phosphoric acid tris(2-chloro-1-methylethyl) ester;EINECS 237-158-7;C9H18Cl3O4P;TCPP phosphate cpd;CAS-13674-84-5;BRN 1842347;TCIPP;UNII-CRT22GFY70;TCPP, Tris(1-chloro-2-propyl)phosphate;HSDB 8112;tris(2-chloro-1-methylethyl)phosphate;Flame retardant TCPP;LEVAGARD PP;TOLGARD TMCP;EC 237-158-7;SCHEMBL35713;tris(chloroisopropyl) phosphate;CHEMBL3188873;CHEBI:143728;Tox21_202982;Tox21_303533;tris(2-chloro-1-methylethyl) ester;MFCD00040408;AKOS015899872;NCGC00257407-01;NCGC00260528-01;Tris(2-chloroisopropyl)phosphate (TCPP);J50.405J;CS-0059312;FT-0689156;NS00009572;TRIS(.BETA.-CHLOROISOPROPYL) PHOSPHATE;TRIS(1-METHYL-2-CHLOROETHYL) PHOSPHATE;Flame retardant Tris(2-chloroisopropyl)phosphate;A886642;Phosphoric acid tris(2-chloro-1-methylethyl) ester;Q-201899;Q2454095;PHOSPHORIC ACID TRIS(1-CHLOROPROPANE-2-YL) ESTER;98112-32-4

Tris(2-chloropropyl) phosphate ( TCPP) is a trialkyl phosphate.
Tris(2-chloropropyl) phosphate ( TCPP)is a chlorinated organophosphate.
Organophosphate chemicals have a wide variety of applications and are used as flame retardants, pesticides, plasticizers, and nerve gases.
Tris(2-chloropropyl) phosphate ( TCPP) is structurally similar to several other organophosphate flame retardants, such as tris(2-chloroethyl) phosphate (TCEP) and tris(chloropropyl)phosphate (TCPP).
Tris(2-chloropropyl) phosphate ( TCPP) and these other chlorinated organophosphate flame retardants are all sometimes referred to as "chlorinated tris".

Presence in the environment
Tris(2-chloropropyl) phosphate ( TCPP) is an additive flame retardant, meaning that it is not chemically bonded to treated materials.
Additive flame retardants are thought to be more likely to be released into the surrounding environment during the lifetime of the product than chemically bonded, or reactive, flame retardants.
Tris(2-chloropropyl) phosphate ( TCPP) degrades slowly in the environment and is not readily removed by waste water treatment processes.

Indoors
Tris(2-chloropropyl) phosphate ( TCPP) has been detected in indoor dust, although concentrations vary widely.
A study of house dust in the U.S. found that over 96% of samples collected between 2002 and 2007 contained Tris(2-chloropropyl) phosphate ( TCPP) at an average concentration of over 1.8 ppm, while the highest was over 56 ppm. TDCPP was also detected in 99% of dust samples collected in 2009 in the Boston area from offices, homes, and vehicles.
The second study found an average concentration similar to that of the previous study but a greater range of concentrations: one sample collected from a vehicle contained over 300 ppm Tris(2-chloropropyl) phosphate ( TCPP) in the dust.
Similar concentrations have been reported for dust samples collected in Europe and Japan.

Tris(2-chloropropyl) phosphate ( TCPP) has also been measured in indoor air samples.
Tris(2-chloropropyl) phosphate ( TCPP)'s detection in air samples, however, is less frequent and generally at lower concentrations than other organophosphate flame retardants such as TCEP and TCPP, likely due to its lower vapor pressure.

Outdoors
Although Tris(2-chloropropyl) phosphate ( TCPP) is generally found at the highest concentrations in enclosed environments, such as homes and vehicles, it is widespread in the environment.
Diverse environmental samples, ranging from surface water to wildlife tissues, have been found to contain Tris(2-chloropropyl) phosphate ( TCPP).
The highest levels of contamination are generally near urban impacted areas; however, samples from even relatively remote reference sites have contained TDCPP.

Tris(2-chloropropyl) phosphate ( TCPP) Chemical Properties
Melting point: -39.9°C
Boiling point: 270°C
Density: 1.28
Refractive index: 1.460～1.466 (20℃/D)
Fp: -218 °C
Storage temp.: Sealed in dry,Room Temperature
Solubility: DMSO (Slightly), Methanol (Slightly)
Form: liquid
Color: Clear Colourless
Odor: mild odor
Water Solubility: BRN: 1842347
Stability: Moisture Sensitive
InChIKey: KVMPUXDNESXNOH-UHFFFAOYSA-N
CAS DataBase Reference: 13674-84-5(CAS DataBase Reference)
NIST Chemistry Reference: Tris(2-chloropropyl) phosphate ( TCPP) (3:1)(13674-84-5)
EPA Substance Registry System: Tris(2-chloropropyl) phosphate ( TCPP) (13674-84-5)

Tris(2-chloropropyl) phosphate ( TCPP) is clear colorless oily liquid with high water solubility and low lipophilicity (as indicated by logKOW).
Tris(2-chloropropyl) phosphate ( TCPP) ismanufactured as a reactionmixture, which contains four isomers.

Uses
Tris(2-chloropropyl) phosphate ( TCPP) is a flame retardant of low hydrolytic stability, used in polyurethane (PU) rigid and flexible foam, PVC, EVA, phenolics and epoxy resin.

Flame retardant
Until the late 1970s, Tris(2-chloropropyl) phosphate ( TCPP) was used as a flame retardant in children’s pajamas in compliance with the U.S. Flammable Fabrics Act of 1953.
This use was discontinued after children wearing fabrics treated with a very similar compound, tris(2,3-dibromopropyl) phosphate, were found to have mutagenic byproducts in their urine.

Following the 2005 phase-out of PentaBDE in the United States, Tris(2-chloropropyl) phosphate ( TCPP) became one of the primary flame retardants used in flexible polyurethane foam used in a wide variety of consumer products, including automobiles, upholstered furniture, and some baby products.
Tris(2-chloropropyl) phosphate ( TCPP) can also be used in rigid polyurethane foam boards used for building insulation.
In 2011 Tris(2-chloropropyl) phosphate ( TCPP) was reported that TDCPP was found in about a third of tested baby products.
Some fabrics used in camping equipment are also treated with Tris(2-chloropropyl) phosphate ( TCPP) to meet CPAI-84, a standard established by the Industrial Fabrics Association International to evaluate the flame resistance of fabrics and other materials used in tents.
Current total production of Tris(2-chloropropyl) phosphate ( TCPP) is not well known. In 1998, 2002, and 2006, production in the United States was estimated to be between 4,500 and 22,700 metric tons, and thus Tris(2-chloropropyl) phosphate ( TCPP) is classified as a high production volume chemical.

Toxicology
Tris(2-chloropropyl) phosphate ( TCPP) is considered a suspected carcinogenic, suspected reprotoxic, and suspected PBT (persistent, bioaccumulative and toxic) and is a potential endocrine disruptor (ECHA, 2019).
Thus, the presence of Tris(2-chloropropyl) phosphate ( TCPP) in the receiving water can affect aquatic organisms and potentially affect human health.
Tris(2-chloropropyl) phosphate ( TCPP) is probably combustible.
Tris(2-chloropropyl) phosphate ( TCPP) may hydrolyze under acidic or alkaline conditions.

Human exposure
Humans are thought to be exposed to Tris(2-chloropropyl) phosphate ( TCPP) and other flame retardants through several routes, including inhalation, ingestion, and skin contact with treated materials.
Rodent studies show that Tris(2-chloropropyl) phosphate ( TCPP) is readily absorbed through the skin and gastrointestinal tract.
Infants and young children are expected to have the highest exposure to Tris(2-chloropropyl) phosphate ( TCPP) and other indoor contaminants for several reasons.
Compared to adults, children spend more time indoors and closer to the floor, where they are exposed to higher amounts of dust particles.
In addition, they frequently put their hands and other objects into their mouths without washing.

Several studies show that Tris(2-chloropropyl) phosphate ( TCPP) can accumulate in human tissues.
Tris(2-chloropropyl) phosphate ( TCPP) has been detected in semen, fat, and breast milk, and the metabolite bis (1,3-dichloropropyl) phosphate (BDCPP) has been detected in urine.

DESCRIPTION:
Tris(2-ethylhexyl)phosphate is a clear colorless to pale yellow liquid with a slight sharp odor.
Tris(2-ethylhexyl) phosphate is a trialkyl phosphate.
Tris(2-ethylhexyl) Phosphate is used as a phosphorous flame retardant.

CAS: 78-42-2
European Community (EC) Number: 201-116-6
IUPAC Name: tris(2-ethylhexyl) phosphate
Molecular Formula: C24H51O4P


USES OF TRIS (2-ETHYLHEXYL) PHOSPHATE:
Tris (2-ethylhexyl) phosphate (TEHP) has been widely used as a plasticizer, fire retardant and solvent.
As a plasticizer, Tris (2-ethylhexyl) phosphate is used as a component of vinyl stabilizers, grease additives and flame-proofing compositions for vinyl plastic and synthetic rubber compounds.
As a fire retardant, Tris (2-ethylhexyl) phosphate is used in consumer products, such as clothing.

As a solvent, Tris (2-ethylhexyl) phosphate is used as a co-solvent to produce hydrogen peroxide.
The world production of Tris (2-ethylhexyl) phosphate was estimated to be between 1000 to 5000 tons per year
Occupational exposure may occur through inhalation and dermal contact with TEHP at workplaces
The general population may be exposed to Tris (2-ethylhexyl) phosphate via ingestion of contaminated food and drinking water or via dermal contact with Tris (2-ethylhexyl) phosphate -treated clothing.

Tris(2-ethylhexyl) Phosphate is used as a phosphorous flame retardant.
Tris(2-ethylhexyl) Phosphate is Used as a plasticizer in the preparation of a new potentiometric membrane sensor.

APPLICATIONS OF TRIS(2-ETHYLHEXYL) PHOSPHATE:
Tris(2-ethylhexyl) Phosphate is a phosphate plasticizer offering excellent low temperatures properties as well as good resistance to weathering.
Tris(2-ethylhexyl) Phosphate is suitable for use in many types of polymers including flexible PVC, PUR, NBR, SBR and EPDM.

Tris(2-ethylhexyl) Phosphate is a strong, moderately polar solvent.
Tris(2-ethylhexyl) Phosphate is also used as a solvent in the production of hydrogen peroxide, as a carrier for pigments in the manufacture of pigment pastes for plastics and as an additive for mineral oils.

SAFETY INFORMATION ABOUT TRIS(2-ETHYLHEXYL)PHOSPHATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


CHEMICAL AND PHYSICAL PROPERTIES OF TRIS(2-ETHYLHEXYL)PHOSPHATE:
Molecular Weight: 434.6 g/mol
XLogP3-AA 8.9
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 21
Exact Mass 434.35249710 g/mol
Monoisotopic Mass 434.35249710 g/mol
Topological Polar Surface Area 44.8Ų
Heavy Atom Count 29
Formal Charge 0
Complexity 345
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 3
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
vapor pressure: 2.1 mmHg ( 20 °C)
Quality Level: 200
Assay: 97%
refractive index: n20/D 1.444 (lit.)
bp: 215 °C/4 mmHg (lit.)
Density: 0.92 g/mL at 20 °C (lit.)
CAS number 78-42-2
EC number 201-116-6
Hill Formula C₂₄H₅₁O₄P
Chemical formula [CH₃(CH₂)₃CH(C₂H₅)CH₂O]₃PO
Molar Mass 434.63 g/mol
HS Code 2919 90 00
Boiling point 210 °C (5 hPa) decomposes
Density 0.92 g/cm3 (20 °C)
Flash point 170 °C
Ignition temperature 370 °C
Melting Point pH value 7 (H₂O, 20 °C)
Vapor pressure Solubility Chemical Formula:
C24H51O4P
Flash Point: 305°F (NTP, 1992)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: 698°F (NTP, 1992)
Melting Point: -94°F (NTP, 1992)
Vapor Pressure: 1.9 mmHg at 392°F (NTP, 1992)
Vapor Density (Relative to Air): 14.95 (NTP, 1992)
Specific Gravity: 0.9262 at 68°F (NTP, 1992)
Boiling Point: 374 to 451°F at 760 mmHg (decomposes) (NTP, 1992)
Molecular Weight: 434.65 (NTP, 1992)
Water Solubility: less than 1 mg/mL at 64°F
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.92400 @ 25.00 °C.
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
Soluble in:
water, 0.6 mg/L @ 24C (exp)
water, 1.461e-005 mg/L @ 25 °C (est)


SYNONYMS OF TRIS(2-ETHYLHEXYL)PHOSPHATE:
2-ethyl-1-hexanol phosphate
tris(2-ethylhexyl)phosphate
Tris(2-ethylhexyl) phosphate
78-42-2
Tris(2-ethylhexyl)phosphate
Disflamoll TOF
Kronitex TOF
Phosphoric acid, tris(2-ethylhexyl) ester
Flexol TOF
Flexol plasticizer TOF
Tri(2-ethylhexyl) phosphate
2-Ethyl-1-hexanol phosphate
Tris(ethylhexyl) phosphate
Tri(2-ethylhexyl)phosphate
1-Hexanol, 2-ethyl-, phosphate
NCI-C54751
TEHP
Phosphoric acid, tris(ethylhexyl) ester
Tri(ethylhexyl) phosphate
2-Ethylhexanol, phosphate triester
Tris-(2-ethylhexyl)fosfat
NSC 407921
BQC0BKB72S
TOF
DTXSID0021414
NSC-407921
Phosphoric Acid Tris(2-ethylhexyl) Ester
DTXCID801414
Triethylhexyl phosphate
Tris(2-ethylhexy)phosphate
CAS-78-42-2
CCRIS 615
HSDB 2562
Tris-(2-ethylhexyl)fosfat [Czech]
EINECS 201-116-6
UNII-BQC0BKB72S
Tris-2(2-ethylhexyl)fosfat [Czech]
BRN 1715839
Tris-2(2-ethylhexyl)fosfat
AI3-07852
Amgard TOF
MFCD00009491
1-Hexanol, phosphate
Phosphoric acid, tris(2-ethylhexyl)ester
Trioctyl Phosphate (TOP)
Tris(2-ethylhexl)phosphate
EC 201-116-6
SCHEMBL35485
tris-(2-ethylhexyl)phosphate
MLS002415769
Phosphoric Acid Trioctyl Ester
CHEMBL1562290
2-Ethylhexanol phosphate (3:1)
CHEBI:181994
HMS3039O17
Phosphoric acid tris(2-ethylhexyl)
Tox21_201369
Tox21_300321
NSC407921
Tris(2-ethylhexyl) phosphate, 97%
AKOS015843194
CS-W009670
NCGC00091821-01
NCGC00091821-02
NCGC00091821-03
NCGC00254160-01
NCGC00258921-01
SMR001370923
P1022
TRIS(2-ETHYLHEXYL) PHOSPHATE [HSDB]
WLN: 4Y2&1OPO&O1Y4&2&O1Y4&2
A865029
Q2454094
Tris(2-ethylhexyl) phosphate, Selectophore(TM), >=99.0%
Tris(2-ethylhexyl) phosphate [ACD/IUPAC Name]
2-Ethylhexyl phosphate [ACD/IUPAC Name]
Phosphate de tris(2-éthylhexyle) [French] [ACD/IUPAC Name]
Phosphoric acid, tris(2-ethylhexyl) ester [ACD/Index Name]
Phosphoric acid, tris(2-ethylhexyl)ester
Tri(2-ethylhexyl) phosphate
Tri(2-ethylhexyl)phosphate
Tris(2-ethylhexyl)phosphat [German] [ACD/IUPAC Name]
UNII:BQC0BKB72S
1-Hexanol, 2-ethyl-, phosphate
201-116-6 [EINECS]
2-ETHYL-1-HEXANOL PHOSPHATE
2-Ethylhexanol phosphate (3:1)
2-Ethylhexanol, phosphate triester
4Y2&1OPO&O1Y4&2&O1Y4&2 [WLN]
78-42-2 [RN]
Amgard TOF
disflamoll tof
Flexol plasticizer TOF
flexol tof
kronitex tof
MFCD00009491 [MDL number]
phosphoric acid tris-(2-ethylhexyl) ester
Phosphoric acid tris(2-ethylhexyl) ester
Phosphoric acid, tris (2-ethylhexyl) ester
Phosphoric acid, tris(ethylhexyl) ester
TOF
tri-(2-ethylhexyl) phosphate
Tri(ethylhexyl) phosphate
triethylhexyl phosphate
trioctyl phosphate [ACD/IUPAC Name]
Tris(2-ethylhexy)phosphate
Tris-(2-ethylhexyl)fosfat [Czech]
Tris-(2-ethylhexyl)phosphate
TRIS(2-ETHYLHEXYL)PHOSPHATE
Tris(ethylhexyl) phosphate
Tris-2(2-ethylhexyl)fosfat

SYNONYMS 1,3,5-Triazine, 2,4,6-tris[1,1'-biphenyl]-4-yl-;Tinosorb A2B;Tris-biphenyl triazine [INCI];2,4,6-Tris(p-biphenylyl)-s-triazine;S-Triazine, 2,4,6-tri-4-biphenylyl CAS NO:31274-51-8

SYNONYMS Sodium Citrate Dihydrate; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, dihydrate;CAS NO. 6132-04-3

Trisiloxane is a colorless and odorless liquid.
Trisiloxane is a type of siloxane compound with three silicon atoms and six oxygen atoms.
Trisiloxane is soluble in both water and many organic solvents.

CAS Number: 540-97-6



APPLICATIONS


Trisiloxane is used as an emulsifier in the production of personal care products like shampoo, conditioner, and lotions.
Trisiloxane is used as a surfactant in agricultural formulations to improve the spread of pesticides and herbicides.

Trisiloxane is used as an antifoaming agent in industrial processes such as paper production and wastewater treatment.
Trisiloxane is used as a mold release agent in the manufacturing of rubber and plastics.

Trisiloxane is used as an ingredient in automotive care products like car wax and polish.
Trisiloxane is used as a lubricant in metalworking processes to reduce friction and improve tool life.

Trisiloxane is used as a solvent in the chemical industry for the synthesis of various compounds.
Trisiloxane is used as a processing aid in the food industry for the production of baked goods, confectionery, and frozen desserts.
Trisiloxane is used in the production of polyurethane foam to improve cell structure and foam quality.

Trisiloxane is used as a defoamer in oil and gas drilling operations to prevent the buildup of foam.
Trisiloxane is used in the production of adhesives to improve bonding and reduce curing time.

Trisiloxane is used in the textile industry as a softening agent for fabrics and fibers.
Trisiloxane is used as a cleaning agent in household and industrial applications.

Trisiloxane is used as a drying agent in coatings and paints to improve drying time and reduce surface defects.
Trisiloxane is used as an additive in the production of silicone rubber to improve the processing and handling properties.
Trisiloxane is used as a conditioning agent in hair care products to improve combability and manageability.

Trisiloxane is used as a dispersant in the pigment and ink industry to improve color intensity and stability.
Trisiloxane is used as a foaming agent in the production of foam insulation and packaging materials.

Trisiloxane is used as a wetting agent in the production of emulsions and suspensions.
Trisiloxane is used in the production of high-performance coatings and sealants.

Trisiloxane is used as an anti-blocking agent in plastic films and sheets to prevent sticking.
Trisiloxane is used as a processing aid in the rubber industry to improve mixing and reduce viscosity.
Trisiloxane is used as an anti-corrosion agent in the metalworking industry.

Trisiloxane is used in the production of industrial detergents and cleaning agents.
Trisiloxane is used as a conditioning agent in fabric softeners to improve softness and reduce static cling.


Trisiloxane has a variety of applications across different industries. Some of its major applications include:


Agriculture:
Trisiloxane is used as a surfactant and wetting agent in agricultural formulations to increase the effectiveness of pesticides and herbicides.

Cosmetics:
Trisiloxane is used as an emollient, conditioning agent, and lubricant in cosmetic products such as hair conditioners, skin creams, and lotions.

Textile:
Trisiloxane is used in the textile industry as a hydrophobic finishing agent to impart water and stain resistance to fabrics.

Personal care:
Trisiloxane is used in personal care products such as deodorants and antiperspirants to increase the effectiveness of active ingredients.

Industrial:
Trisiloxane is used as an industrial defoamer to control foam in various processes such as pulp and paper production.

Adhesives and sealants:
Trisiloxane is used as a wetting agent and dispersant in the production of adhesives and sealants to improve their flow and adhesion properties.

Construction:
Trisiloxane is used as a water repellent in construction materials such as concrete, masonry, and stucco.

Automotive:
Trisiloxane is used as an anti-foaming agent in automotive fluids such as engine oil, transmission fluid, and brake fluid.

Agriculture:
Trisiloxane is also used in the agriculture industry as a spray adjuvant to improve the efficacy of agrochemicals.

Food and beverage:
Trisiloxane is used as a defoaming agent in the production of food and beverage products such as beer, soft drinks, and fruit juices.

Paints and coatings:
Trisiloxane is used as a leveling agent and defoaming agent in the production of paints and coatings to improve their performance.

Paper and pulp:
Trisiloxane is used as a defoamer in the production of paper and pulp to reduce foam formation during processing.

Plastics:
Trisiloxane is used as a processing aid in the production of plastics to improve their flow properties.

Rubber:
Trisiloxane is used as a lubricant and processing aid in the production of rubber products.

Fuel and lubricant:
Trisiloxane is used as an anti-foaming agent and viscosity improver in fuel and lubricant formulations.

Metalworking:
Trisiloxane is used as a lubricant and anti-foaming agent in metalworking fluids.

Water treatment:
Trisiloxane is used as a coagulant aid and flocculant in water treatment processes to improve the efficiency of the treatment.

Textile auxiliaries:
Trisiloxane is used as a textile auxiliary in the production of dyeing and finishing agents.

Petroleum industry:
Trisiloxane is used as a flow improver in crude oil transportation.

Surface coatings:
Trisiloxane is used as a surface coating agent to provide water repellency to various substrates.

Firefighting:
Trisiloxane is used as a foam suppressant in firefighting foams.

Metal cleaning:
Trisiloxane is used as a surfactant in metal cleaning formulations.

Industrial cleaning:
Trisiloxane is used as a cleaning agent in industrial cleaning formulations.

Pharmaceuticals:
Trisiloxane is used as an ingredient in some pharmaceutical formulations.

Polymer processing:
Trisiloxane is used as a processing aid in the polymer processing industry to improve the flow and molding properties of the polymers.


Trisiloxane is commonly used as a surfactant in a variety of personal care and cleaning products.
Trisiloxane can be found in shampoos, conditioners, and other hair care products to improve wetting and conditioning properties.
In skincare products, trisiloxane can help improve the texture and feel of creams and lotions.

Trisiloxane is often used as a lubricant in industrial applications, such as metalworking and textile manufacturing.
Trisiloxane can also be used as a foam control agent in the production of polyurethane foam.

Trisiloxane is used as a spreading agent in agricultural applications to help improve the effectiveness of herbicides and pesticides.
In the construction industry, trisiloxane is used as a water repellent and to improve the durability of building materials.

Trisiloxane can also be used as a mold release agent in the production of concrete and other construction materials.
Trisiloxane is used in the automotive industry as an additive to improve the performance of engine oils and other lubricants.

Trisiloxane can also be found in windshield washer fluids as a de-icing agent.
In the electronics industry, trisiloxane is used as a component in electronic adhesives and coatings.
Trisiloxane is used in the production of silicone elastomers, which are used in a variety of applications, including medical devices and automotive parts.

Trisiloxane can be used as a water-repellent coating on fabrics, such as outdoor clothing and tents.
Trisiloxane is used as a foam control agent in the production of polyurethane foam for furniture and bedding.

Trisiloxane can also be found in spray foam insulation products.
In the oil and gas industry, trisiloxane is used as a defoamer and lubricant in drilling fluids.

Trisiloxane can be used as a solvent in the production of silicone resins and other silicone-based materials.
Trisiloxane can be used as a heat transfer fluid in high-temperature applications.
Trisiloxane is used as a coating on contact lenses to improve comfort and clarity.

In the food industry, trisiloxane is used as a lubricant in food processing equipment.
Trisiloxane can also be used as a coating on food packaging to improve moisture resistance.

Trisiloxane is used in the production of silicone-based inks and coatings for printing and graphic arts applications.
Trisiloxane can be used as a component in sealants and adhesives used in the construction industry.

Trisiloxane is used as a component in some personal care products, such as anti-aging creams and hair serums.
Trisiloxane can also be found in some industrial cleaners and degreasers as a surfactant and solvent.

Trisiloxane is used in the manufacture of personal care products such as hair conditioners and skin moisturizers.
Trisiloxane is used in the production of surfactants and emulsifiers that are used in various industries.
Trisiloxane is used as an antifoaming agent in the food industry.

Trisiloxane is used in the production of high-performance coatings and adhesives.
Trisiloxane is used as a water-repellent coating for glass, ceramic, and other surfaces.

Trisiloxane is used in the production of silicone rubbers and resins.
Trisiloxane is used in the manufacturing of electronic components and semiconductors.

Trisiloxane is used in the production of lubricants and greases for machinery and equipment.
Trisiloxane is used as a mold release agent in the manufacturing of plastic and rubber products.
Trisiloxane is used as a conditioning agent in the textile industry.

Trisiloxane is used in the production of flame retardants for various applications.
Trisiloxane is used as a dispersing agent in the formulation of agricultural chemicals.

Trisiloxane is used as a foam control agent in the production of paper and pulp.
Trisiloxane is used in the formulation of cosmetics such as foundations and lipsticks.
Trisiloxane is used in the production of ceramics and glass fibers.

Trisiloxane is used as a lubricant in the textile industry.
Trisiloxane is used in the formulation of polishes and cleaners for various surfaces.

Trisiloxane is used in the production of polyurethane foams and elastomers.
Trisiloxane is used as a solvent for various chemical reactions.
Trisiloxane is used as a wetting agent in the formulation of paints and coatings.

Trisiloxane is used in the manufacturing of plastic films and sheets.
Trisiloxane is used in the formulation of printing inks and toners.

Trisiloxane is used as a heat transfer fluid in industrial processes.
Trisiloxane is used in the production of automotive parts such as gaskets and seals.
Trisiloxane is used as a binder in the formulation of concrete and construction materials.



DESCRIPTION


Trisiloxane is a chemical compound with the molecular formula Si3H8O2.
Trisiloxane is a type of siloxane, which is a class of organosilicon compounds.

Trisiloxane is a clear, colorless liquid with a mild, pleasant odor.
Trisiloxane is highly soluble in water and is nonflammable.

Trisiloxane is primarily used as a surfactant, which is a substance that helps to reduce the surface tension of a liquid.
Trisiloxane is commonly used in the production of personal care products, such as shampoos, conditioners, and lotions, to improve their wetting ability and to help the products spread more evenly over the skin or hair.

Trisiloxane is also used as a foam control agent in various industrial processes, including in the production of paints and coatings, pulp and paper manufacturing, and metalworking.
Its ability to reduce surface tension makes it useful for preventing the formation of foam during these processes, which can interfere with the quality and efficiency of the end product.

Additionally, trisiloxane is used as a wetting agent in agricultural formulations to help improve the absorption and spreading of pesticides, herbicides, and other agricultural chemicals.
Trisiloxane can also be used as an additive in the production of silicone-based polymers and resins.

Other applications of trisiloxane include its use as a lubricant and as an ingredient in the production of adhesives and sealants.
Trisiloxane is also used in the formulation of household cleaning products, such as laundry detergents and dish soaps, to improve their cleaning performance and reduce streaking.

Overall, trisiloxane is a versatile chemical with a wide range of applications, primarily due to its ability to reduce surface tension and improve wetting and spreading properties of liquids.


Trisiloxane is a colorless and odorless liquid.
Trisiloxane is a type of siloxane compound with three silicon atoms and six oxygen atoms.
Trisiloxane is soluble in both water and many organic solvents.

Trisiloxane has a relatively low boiling point and is therefore easily vaporized.
Trisiloxane has good wetting and spreading properties.

Trisiloxane is commonly used as a surfactant in a variety of applications.
Trisiloxane can lower surface tension, making it useful in emulsification and foam stabilization.

Trisiloxane can also be used as a lubricant and release agent due to its low surface tension.
Trisiloxane is commonly used in personal care products such as shampoos and conditioners.
Trisiloxane can help to improve the wetting ability of these products on hair and skin.

Trisiloxane is also used as a defoaming agent in the production of polyurethane foam.
Trisiloxane can reduce the formation of bubbles during the manufacturing process.

Trisiloxane is used as an ingredient in agricultural products such as herbicides and insecticides.
Trisiloxane can help these products to spread more evenly across plant surfaces.

Trisiloxane is used in the formulation of inkjet printer inks as a solvent and wetting agent.
Trisiloxane can help to improve the printing quality and speed.
Trisiloxane is used in the manufacturing of silicone rubber.

Trisiloxane can improve the flow and mold release properties of the rubber.
Trisiloxane can be used as a mold release agent in the production of plastic parts.

Trisiloxane can help to prevent sticking and improve part release.
Trisiloxane is used as a lubricant and release agent in the production of molded glass products.
Trisiloxane can help to prevent sticking and improve the surface finish of the glass.

Trisiloxane is used in the textile industry as a wetting agent and to improve dye penetration.
Trisiloxane can help to reduce the amount of dye needed and improve color fastness.
Trisiloxane is a versatile compound with many applications in a range of industries.



PROPERTIES


Chemical formula: C3H10O2Si3
Molecular weight: 222.48 g/mol
Appearance: Colorless to light yellow liquid
Density: 0.891 g/cm3 at 20°C
Boiling point: 130-131°C
Melting point: -70°C
Flash point: 35-37°C
Solubility: Insoluble in water; soluble in many organic solvents
Vapor pressure: 10 mm Hg at 25°C
Refractive index: 1.422 at 25°C
Viscosity: 1.6 cSt at 25°C
Surface tension: 19.5 mN/m at 25°C
Dielectric constant: 2.90 at 25°C
pH: Neutral
Odor: Mild, characteristic
Flammability: Flammable liquid, with a flash point below 60°C
Autoignition temperature: 260°C
Explosive limits: 1.1-14% (volume)
Corrosivity: Corrosive to metals
Oxidizing properties: Not classified as oxidizing agent
Stability: Stable under normal conditions of use and storage
Hazardous decomposition products: Carbon monoxide, carbon dioxide, silicon dioxide
Hazardous polymerization: Will not occur
Environmental hazards: Not considered to be an environmental hazard
Health hazards: May cause irritation to skin, eyes, and respiratory system upon prolonged exposure. May be harmful if ingested.
Reactivity: Reacts with strong oxidizing agents and acids, and can undergo hydrolysis in the presence of moisture.



FIRST AID


Inhalation:

If inhaled, remove the person to fresh air immediately.
If the person is not breathing, provide artificial respiration.
Seek immediate medical attention if the person has difficulty breathing or shows other signs of respiratory distress.


Skin Contact:

Remove any contaminated clothing and rinse the affected skin with plenty of water for at least 15 minutes.
If skin irritation or redness develops, seek medical attention.


Eye Contact:

Immediately flush the affected eye(s) with plenty of water for at least 15 minutes, while holding the eyelid(s) open.
Seek immediate medical attention if irritation or pain persists.


Ingestion:

Rinse the mouth with water, but do not induce vomiting.
Seek immediate medical attention if a large amount of the chemical is swallowed, or if the person shows signs of vomiting or convulsions.



HANDLING AND STORAGE


Handling:

Trisiloxane should be handled with care to prevent skin and eye contact, inhalation, and ingestion.
Operators should wear personal protective equipment (PPE) such as gloves, goggles, and respiratory protection when handling Trisiloxane.
In case of skin contact, wash the affected area thoroughly with soap and water.

In case of eye contact, flush the eyes with plenty of water for at least 15 minutes and seek medical attention.
If Trisiloxane is inhaled, move the affected person to fresh air and seek medical attention immediately.
If swallowed, do not induce vomiting and seek medical attention immediately.


Storage:

Trisiloxane should be stored in a cool, dry, and well-ventilated area, away from heat, sparks, and flames.
It should be stored in a tightly sealed container, away from incompatible materials such as strong acids, strong bases, and oxidizers.
Containers of Trisiloxane should be properly labeled with the product name, composition, and hazard warnings.

Do not store Trisiloxane near food, beverages, or animal feed.
Keep Trisiloxane out of the reach of children and unauthorized personnel.
Check the container regularly for leaks and damage.


Transportation:

Trisiloxane should be transported in a properly labeled, sealed, and secured container to prevent spills or leakage.
The container should be placed in a well-ventilated area, away from heat sources and incompatible materials.

Transportation of Trisiloxane should comply with local, state, and federal regulations.
Drivers transporting Trisiloxane should be trained and certified to handle hazardous materials.
In case of a spill or leak during transportation, follow the emergency response procedures and contact the appropriate authorities immediately.


Disposal:

Trisiloxane should be disposed of in accordance with local, state, and federal regulations.
Do not dispose of Trisiloxane in household or municipal waste streams.
Consult with a licensed waste disposal company for safe disposal options.
Containers that previously held Trisiloxane should be properly cleaned and recycled or disposed of according to the manufacturer's instructions.



SYNONYMS


Triethylsiloxane
1,1,1-Tris(dimethylsilyloxy)silane
Tri(trimethylsilyloxy)silane
Tris(trimethylsiloxy)silane
Trialkylsiloxy silane
TES
TMSO3
TTS
1,1,1-Tris(trimethylsilyloxy)silane
Silane, tris(trimethylsilyloxy)-
Tris(trimethylsilyl) orthosilicate
Tri(trimethylsilyl) silicate
Silicic acid, tri(trimethylsilyl) ester
Tris(trimethylsilyloxy)silicon
Silicon tris(trimethylsiloxy)
TMSOT
Tris(trimethylsilyl)silanol
Tris(trimethylsilyl) silicate
Tri(trimethylsilyl) orthosilicate
Tri(trimethylsilyl) silicic acid
Triethylsilyloxysilane
Trialkylsilyloxy silane
Tris(trimethylsilyloxy) silicium
Triethoxysilane trimethylsilyl derivative
Silicon tris(trimethylsilyloxy)
Triethylsilanol
1,1,1-Trisiloxane
Trisilicon tetrahydride
Triethylsiloxane
Siloxane, tris(triethylsiloxy)-
Tris(triethylsilyl)oxide
Triethylsilyl ether
TTSO
Silanetriol, triethyl-
Triethylsilyl alcohol
Tris(triethylsilyl)silanol
Trisiloxane, [(triethylsilyl)oxy]-
Triethylsiloxysilane
Triethoxytrisilane
Tris(triethoxysilyl)amine
Tris(triethoxysilyl)phosphate
Triethylsilyltrifluoroacetate
Triethylsilylethynylbenzene
Tris(2,2,6,6-tetramethyl-3,5-heptanedionato)europium(III)
Tris(trifluoroacetylacetonato)samarium(III)
Tris(acetylacetonato)iron(III)
Tris(ethylenediamine)cobalt(III)chloride
Tris(trimethylsilyl)phosphine
Tris(trimethylsilyl)silane
Tris(trimethylsilyl)amine

Trisiloxane Polyether is a type of surfactant that contains a silicone-based (trisiloxane) backbone and polyether side chains.
Trisiloxane Polyether is a clear liquid that is soluble in both water and organic solvents.



APPLICATIONS


Trisiloxane Polyether has several applications in various industries, including:

Coatings:
Trisiloxane Polyether is used as a surfactant in coatings to improve wetting and leveling properties.


Personal care products:
Trisiloxane Polyether is used as a surfactant and emulsifier in personal care products, such as shampoos and body washes, to improve their texture and stability.


Agriculture:
Trisiloxane Polyether is used as a spray adjuvant in agriculture to improve the performance of pesticides and herbicides.


Textiles:
Trisiloxane Polyether is used as a softener and lubricant in textile manufacturing to improve the hand-feel and processing of fabrics.


Foam control:
Trisiloxane Polyether is used as a foam control agent in industrial processes to reduce foam formation and improve process efficiency.


Automotive:
Trisiloxane Polyether is used as an additive in automotive fluids, such as brake fluids and engine oils, to improve their lubricity and anti-wear properties.


Construction:
Trisiloxane Polyether is used as a water repellent in construction materials, such as concrete and masonry, to improve their durability and resistance to moisture.


Electronics:
Trisiloxane Polyether is used as a surface treatment in electronics manufacturing to improve the adhesion and performance of coatings and adhesives.


Food processing:
Trisiloxane Polyether is used as a processing aid in food manufacturing to improve the efficiency and quality of production processes.


Pharmaceuticals:
Trisiloxane Polyether is used as an emulsifier and solubilizer in pharmaceutical formulations to improve their stability and bioavailability.


Trisiloxane Polyether is commonly used as a surfactant in coatings to improve their wetting and leveling properties.
Trisiloxane Polyether is often used as an emulsifier and surfactant in personal care products such as shampoos, conditioners, and body washes.
In the agriculture industry, Trisiloxane Polyether is used as a spray adjuvant to improve the performance of pesticides and herbicides.

Trisiloxane Polyether is often used as a softener and lubricant in textile manufacturing to improve the feel and processing of fabrics.
Trisiloxane Polyether is used as a foam control agent in industrial processes to reduce foam formation and improve process efficiency.

In automotive fluids such as brake fluids and engine oils, Trisiloxane Polyether is added to improve lubricity and anti-wear properties.
Trisiloxane Polyether is used as a water repellent in construction materials such as concrete and masonry to improve their durability and resistance to moisture.

Trisiloxane Polyether is used as a surface treatment in electronics manufacturing to improve the adhesion and performance of coatings and adhesives.
In food manufacturing, Trisiloxane Polyether is used as a processing aid to improve the efficiency and quality of production processes.

Trisiloxane Polyether is used as an emulsifier and solubilizer in pharmaceutical formulations to improve their stability and bioavailability.
Trisiloxane Polyether is used in the manufacture of surfactants and detergents.
Trisiloxane Polyether is used as a wetting agent in the production of polyurethane foam.

In the petroleum industry, Trisiloxane Polyether is used as a lubricant and anti-foaming agent.
Trisiloxane Polyether is used as a defoaming agent in the pulp and paper industry.

Trisiloxane Polyether is used as a leveling agent in printing inks and coatings.
In metalworking fluids, Trisiloxane Polyether is used as a lubricant and corrosion inhibitor.

Trisiloxane Polyether is used as a wetting agent in the production of silicone rubber.
Trisiloxane Polyether is used as an emulsifier in the production of food additives and flavors.

Trisiloxane Polyether is used as a surfactant in the production of detergents and cleaners.
In the textile industry, Trisiloxane Polyether is used as a lubricant and dyeing aid.
Trisiloxane Polyether is used as a processing aid in the production of paper and cardboard.

Trisiloxane Polyether is used as a surfactant and defoamer in the production of latex paints.
Trisiloxane Polyether is used as a foam control agent in the production of polyurethane foam.

In the water treatment industry, Trisiloxane Polyether is used as a coagulant aid and scale inhibitor.
Trisiloxane Polyether is used as a wetting agent and emulsifier in the production of agrochemicals.

Trisiloxane Polyether is used as a dispersant in the production of pigments and dyes.
Trisiloxane Polyether is used as a plasticizer in the production of plastics and resins.
Trisiloxane Polyether is used as a release agent in the production of molded rubber and plastic parts.

In the cosmetics industry, Trisiloxane Polyether is used as a humectant and skin conditioning agent.
Trisiloxane Polyether is used as a surfactant and emulsifier in the production of petroleum products such as lubricating oils and fuel additives.


Trisiloxane Polyether is used as a surfactant in personal care products such as shampoos and conditioners.
Trisiloxane Polyether acts as a wetting agent in printing inks, coatings, and adhesives.
Trisiloxane Polyether enhances the water resistance of textiles and leather goods.

Trisiloxane Polyether improves the slip properties of packaging films and coatings.
Trisiloxane Polyether aids in the dispersion of pigments and other additives in coatings.

Trisiloxane Polyether is used in the production of anti-foaming agents for industrial processes.
Trisiloxane Polyether acts as a dispersant in ceramic and glass manufacturing.

Trisiloxane Polyether is used as a release agent in the production of molded rubber and plastic products.
Trisiloxane Polyether enhances the spreading and wetting properties of agricultural sprays and formulations.

Trisiloxane Polyether improves the flow properties of cementitious materials and concrete.
Trisiloxane Polyether acts as a leveling agent in coatings and adhesives.
Trisiloxane Polyether is used as a foam stabilizer in the production of polyurethane foams.

Trisiloxane Polyether improves the gloss and clarity of coatings and films.
Trisiloxane Polyether is used as a wetting agent and anti-static agent in the production of electronic components.

Trisiloxane Polyether enhances the release properties of mold releases and casting agents.
Trisiloxane Polyether is used in the production of defoamers and emulsifiers for industrial processes.

Trisiloxane Polyether acts as a lubricant and anti-wear agent in metalworking fluids.
Trisiloxane Polyether enhances the water-repellency of coatings and textiles.

Trisiloxane Polyether is used as a release agent in the production of food packaging and processing equipment.
Trisiloxane Polyether improves the wetting and dispersing properties of inks and pigments in printing applications.
Trisiloxane Polyether acts as a solvent in cleaning and degreasing formulations.

Trisiloxane Polyether is used in the production of optical coatings for lenses and displays.
Trisiloxane Polyether enhances the stain resistance of textiles and carpets.

Trisiloxane Polyether is used as a coupling agent in polymer processing and compounding.
Trisiloxane Polyether improves the adhesion of coatings and adhesives to difficult substrates.

Trisiloxane Polyether acts as a defoaming agent in oil and gas production.
Trisiloxane Polyether enhances the surface smoothness of plastics and films.

Trisiloxane Polyether is used as a leveling and anti-cratering agent in coatings.
Trisiloxane Polyether improves the hydrophobicity of building materials such as stone and concrete.
Trisiloxane Polyether acts as a lubricant and corrosion inhibitor in metalworking and industrial fluids.


Some applications of Trisiloxane Polyether:

Water repellent coatings for textile fibers
Anti-fouling coatings for marine vessels
Wood coatings to enhance water resistance
Release agents for molding processes
Lubricants for moving mechanical parts
Surfactants for foam control in various industries
Adhesives for difficult-to-bond surfaces
Ink and paint additives to improve flow and leveling
Coatings for electronic components to improve water resistance
Soil-repellent treatments for carpets and upholstery
Anti-corrosion coatings for metals
Hydrophobic coatings for optical lenses
Oil and gas recovery
Personal care products such as hair conditioners and skin lotions
Laundry detergents and fabric softeners
Agriculture as an adjuvant in pesticide formulations
Construction as a water repellent for concrete and masonry
Cleaning products as a surfactant and wetting agent
Food packaging to prevent moisture absorption
Paper coatings to improve water resistance and printability



DESCRIPTION


Trisiloxane Polyether is a type of surfactant that contains a silicone-based (trisiloxane) backbone and polyether side chains.
Trisiloxane Polyether is a clear liquid that is soluble in both water and organic solvents.

Trisiloxane Polyether is commonly used as a wetting agent, emulsifier, and dispersant in a wide range of applications, including personal care products, agricultural formulations, and industrial cleaning agents.
Its unique chemical structure allows it to reduce surface tension and enhance spreading and wetting properties, making it a highly effective and versatile surfactant.

Trisiloxane Polyether is a highly efficient surfactant due to its unique chemical structure.
The silicone-based backbone of Trisiloxane Polyether provides excellent stability and durability.
Trisiloxane Polyether is used in a variety of industries, including agriculture, cosmetics, and industrial cleaning.

The polyether side chains in Trisiloxane Polyether allow it to be highly soluble in both water and organic solvents.
Trisiloxane Polyether is known for its excellent wetting and dispersing properties, making it a highly effective emulsifier.

Due to its low surface tension, Trisiloxane Polyether is often used as a wetting agent in agricultural formulations to improve spray coverage.
Trisiloxane Polyether can be used as a foam control agent in industrial processes due to its ability to reduce surface tension and foam generation.

The combination of hydrophobic and hydrophilic properties in Trisiloxane Polyether makes it highly effective at reducing interfacial tension between different phases.
Trisiloxane Polyether is biodegradable and has a low toxicity profile, making it an environmentally friendly option for many applications.
The unique properties of Trisiloxane Polyether allow it to provide enhanced performance and efficiency compared to traditional surfactants.



PROPERTIES


Molecular weight: 1000-5000 g/mol
Density: 1.00-1.10 g/mL
Boiling point: >200°C
Flash point: >100°C
Solubility: soluble in water and most organic solvents
Viscosity: low to moderate
Surface tension: low
Hydrophilicity: high
Thermal stability: good
Chemical stability: good
Biocompatibility: good
Emulsifying ability: good
Foaming ability: good
Lubricating ability: good
Wetting ability: good



FIRST AID


The first aid measures for Trisiloxane Polyether are as follows:

In case of inhalation:

Move the affected person to a well-ventilated area and provide fresh air.
If symptoms persist, seek medical attention.


In case of skin contact:

Remove contaminated clothing and wash the affected area thoroughly with soap and water.
If skin irritation or rash develops, seek medical attention.


In case of eye contact:

Rinse the affected eye(s) with water for several minutes, while holding the eyelid(s) open.
Seek medical attention if irritation persists.


In case of ingestion:

Do not induce vomiting.
Rinse mouth with water and drink plenty of water.
Seek medical attention immediately.
Note: It is important to seek medical attention if any symptoms persist or in case of doubt.



HANDLING AND STORAGE


The handling and storage conditions for Trisiloxane Polyether are as follows:

Storage:

Store in a cool, dry, and well-ventilated area away from direct sunlight, heat, sparks, and flame.


Handling:

Handle with appropriate protective equipment, such as gloves, safety glasses, and respiratory protection if required.
Avoid inhalation of vapors and contact with skin and eyes.
Use in a well-ventilated area or with local exhaust ventilation.


Storage containers:

Use appropriate containers made of compatible materials, such as stainless steel or high-density polyethylene (HDPE).


Shelf life:

The shelf life of Trisiloxane Polyether can vary depending on the storage conditions and the manufacturer's recommendations.
It is recommended to use it within the expiry date mentioned on the label or as specified by the supplier.


Note: Follow the manufacturer's instructions and local regulations regarding handling, storage, and disposal of the product.



SYNONYMS


Poly(oxyethylene)-tris(trimethylsiloxy)silane
Silicone polyether
Trisiloxane ethylene oxide copolymer
Trialkoxy polyether silane
Ethylene oxide terminated polydimethylsiloxane
Siloxane polyalkyleneoxide copolymer
Trialkoxy silane polyether
Ethoxylated trisiloxane
Trialkoxy silane ethylene oxide copolymer
Poly(ethylene oxide)-terminated trimethylsiloxy siloxane
Siloxane-polyalkylene oxide block copolymer
Triethoxysilyl poly(ethylene oxide) copolymer
Polyethylene oxide-terminated polydimethylsiloxane
Poly(dimethylsiloxane)-poly(ethylene oxide) block copolymer
Trisiloxane-polyethylene oxide copolymer
Trimethylsiloxy-terminated polyethylene oxide
Trialkoxy silane-terminated polyethylene oxide
Siloxane-polyether copolymer
Trisiloxane-poly(oxyethylene) copolymer
Polydimethylsiloxane-poly(oxyethylene) copolymer

DESCRIPTION:
Trisodium citrate has the chemical formula of Na3C6H5O7.
Trisodium citrate is sometimes referred to simply as "sodium citrate", though sodium citrate can refer to any of the three sodium salts of citric acid.
Trisodium citrate possesses a saline, mildly tart flavor, and is a mild alkali.

CAS Number: 68-04-2
Molecular Formula: C6H5Na3O7

Trisodium Citrate is one of the sodium salts of citric acid which is found in every living organism, part of the key metabolic pathways in all body cells.
Trisodium Citrate is found in sour fruits such as kiwi, strawberries and many other fruits which has high concentration.
Trisodium Citrate is commercially prepared by fermenting molasses of Aspergillus niger mould.

Citrate is a conjugate base of a weak acid, can function as a buffering agent or acidity regulator by resisting the change in pH.
Trisodium Citrate, also referred to as Sodium Citrate, Trisodium Salt or food additive E331, is the tribasic salt of citric acid.

Trisodium Citrate appears as a white crystalline powder or granular crystals and, given it is a salt, possesses a salty / saline taste with no real detectable odour.
Trisodium Citrate has the CAS number 6132-04-3 and formula Na3C6H5O7.
Trisodium citrate is water-soluble, non-toxic and fully biodegradable.


USES OF TRISODIUM CITRATE:
Trisodium citrate is used in similar applications to citric acid .
These uses include as an acidity regulator in food and drink, as a sequestering agent to prevent limescale inference with soaps and detergents and as an emulsifying agent to aid chemical mixing processes where two separate elements are incapable of mixing (for example oil and water) and helps to keep these mixtures stable once formulated.

Trisodium Citrate in Food:
Trisodium Citrate is a food additive with the E number E331.
Trisodium Citrate is used in a variety of processed food and drink primarily as a flavour enhancer and a preservative.


As an emulsifying agent it is also used in cheesemaking to allow cheese to melt without the separation of oils and fats.
Trisodium citrate in food buffers pH levels to help regulate acidity in a variety of foods to balance taste and is also able to impart a tart / sour flavour in a wide variety of drink products.






APPLICATIONS OF TRISODIUM CITRATE:
Foods:
Sodium citrate is chiefly used as a food additive, usually for flavor or as a preservative.
Its E number is E331.
Sodium citrate is employed as a flavoring agent in certain varieties of club soda.

Trisodium citrate is common as an ingredient in bratwurst, and is also used in commercial ready-to-drink beverages and drink mixes, contributing a tart flavor.
Trisodium citrate is found in gelatin mix, ice cream, yogurt, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine, amongst others.

Trisodium citrate can be used as an emulsifying stabilizer when making cheese.
Trisodium citrate allows the cheese to melt without becoming greasy by stopping the fats from separating.

Buffering:
Speciation diagram for a 10-millimolar solution of citric acid.
The violet curve corresponds to the trisodium citrate.
As a conjugate base of a weak acid, citrate can perform as a buffering agent or acidity regulator, resisting changes in pH.

Trisodium citrate is used to control acidity in some substances, such as gelatin desserts.
Trisodium citrate can be found in the milk minicontainers used with coffee machines.
The compound is the product of antacids, such as Alka-Seltzer, when they are dissolved in water.

The pH of a solution of 5 g/100 ml water at 25 °C is 7.5 – 9.0.
Trisodium citrate is added to many commercially packaged dairy products to control the pH impact of the gastrointestinal system of humans, mainly in processed products such as cheese and yogurt, although it also has beneficial effects on the physical gel microstructure.

Chemistry:
Trisodium citrate is a component in Benedict's qualitative solution, often used in organic analysis to detect the presence of reducing sugars such as glucose.

Medicine:
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions, with Richard Lewisohn determining its correct concentration in 1915.
It continues to be used today in blood-collection tubes and for the preservation of blood in blood banks.

The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism.
Recently, trisodium citrate has also been used as a locking agent in vascath and haemodialysis lines instead of heparin due to its lower risk of systemic anticoagulation.

In 2003, Ööpik et al. showed the use of sodium citrate (0.5 g/kg body weight) improved running performance over 5 km by 30 seconds.
Sodium citrate is used to relieve discomfort in urinary-tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative.
It is a major component of the WHO oral rehydration solution.

Trisodium citrate is used as an antacid, especially prior to anaesthesia, for caesarian section procedures to reduce the risks associated with the aspiration of gastric contents.

Boiler descaling:
Trisodium citrate is a particularly effective agent for removal of carbonate scale from boilers without removing them from operation and for cleaning automobile radiators


CHEMICAL AND PHYSICAL PROPERTIES OF TRISODIUM CITRATE:
Chemical formula Na3C6H5O7
Molar mass 258.06 g/mol (anhydrous), 294.10 g/mol (dihydrate)
Appearance White crystalline powder
Density 1.7 g/cm3
Melting point > 300 °C (572 °F; 573 K) (hydrates lose water ca. 150 °C)
Boiling point Decomposes
Solubility in water Pentahydrate form: 92 g/100 g H2O (25 °C)



SAFETY INFORMATION ABOUT TRISODIUM CITRATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



SYNONYMS OF TRISODIUM CITRATE:
Trisodium citrate [ACD/IUPAC Name] [Wiki]
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:3) [ACD/Index Name]
200-675-3 [EINECS]
68-04-2 [RN]
994-36-5 [RN]
Citrate de trisodium [French] [ACD/IUPAC Name]
Citric Acid Trisodium Salt
MFCD00012462 [MDL number]
RS7A450LGA
Sodium 2-hydroxy-1,2,3-propanetricarboxylate
Sodium Citrate [JAN] [USAN] [Wiki]
Sodium citrate anhydrous
Trinatriumcitrat [German] [ACD/IUPAC Name]
Tris sodium citrate
trisodium 2-hydroxypropane-1,2,3-tricarboxylate
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt
114456-61-0 [RN]
205-623-3 [EINECS]
2-Hydroxy-1,2,3-propanenetricarboxylic acid trisodium salt
2-Hydroxy-1,2,3-propanetricarboxylic acid trisodium salt
2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt
Citnatin
Citrate Concentratedmissing
citrate sodium
citrate trisodium
Citratemissing
Citreme
Citric acid sodium salt anhydrous
Citric acid trisodium salt, anhydrous
Citric acid, trisodium salt
Citrosodina
Citrosodine
Citrosodna
Isolyte E
Natrocitral
Sodium 2-hydroxypropane-1,2,3-tricarboxylate
Sodium citrate (USP)
Sodium citrate buffer
SODIUM CITRATE TRIBASIC
Sodium citrate, anhydrous
Synthesis on demand
tri-sodium citrate
Trisodium citrate anhydrous
tris-sodium citrate
UNII-RS7A450LGA

Sodium Citrate Dihydrate; 2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt, dihydrate;TRISODIUM CITRATE 5,5-HYDRATE; TRISODIUM CITRATE DIHYDRATE; TRISODIUM PHOSPHATE (12HYDRATE) ; TRISODIUM PHOSPHATE ANHYDRATE cas no: 6132-04-3

Trisodium citrate (TSC) is a versatile chemical substance used in a variety of applications in different industries.
In the food industry, Trisodium citrate (TSC) is used as a flavor enhancer, acidity regulator, and emulsifier.
In the medical field, Trisodium citrate (TSC) is used as an anticoagulant but it is also an ingredient in many personal care products.

CAS: 6132-04-3
MF: C6H9Na3O9
MW: 294.1
EINECS: 612-118-5

Synonyms
ANTI-BABOON IGM, BIOTIN;BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE;HYDROXYTRICARBALLYLIC ACID MONOHYDRATE;CITRIC ACID NA3-SALT 2H2O;CITRIC ACID H2O;CITRIC ACID TRISODIUM SALT DIHYDRATE;CITRIC ACID, 3NA, DIHYDRATE;CITRIC ACID-1-HYDRATE;Trisodium citrate dihydrate;Sodium citrate dihydrate;6132-04-3;Sodium citrate tribasic dihydrate;1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate;Sodium citrate hydrate;Citric acid trisodium salt dihydrate;MFCD00150031;B22547B95K;Nauzene;trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate;trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate;DTXSID1049437;SODIUM CITRATE, DIHYDRATE;Citric acid, trisodium salt, dihydrate;N-1560;Sodium citrate hydrous;Natrii citras, dehydrate;Trisodium citrate dihydrate;Citric acid trisodium salt dihydrate;MFCD00130806;tri-sodium citrate dihydrate;TRISODIUM CITRATE DIHYDRATE (II);TRISODIUM CITRATE DIHYDRATE [II];TRISODIUM CITRATE DIHYDRATE (USP MONOGRAPH);TRISODIUM CITRATE DIHYDRATE [USP MONOGRAPH];sodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate;Tricitrasol;Natrum citricum;Emetrol Chewables;Tricitrasol (TN);Sodium citrate; Trisodium 2-hydroxypropane-1,2,3-tricarboxylatedihydrate; Sodium Citrate ;Dihydrate;Sodium citrate (TN);CVS HealthNausea Relief;Emetrol Chewables Orange;Sodium citrate [USP:JAN];Sodiumcitratetribasicdihydrate;EmetrolChewables Mixed Berry;SODIUM CITRATE [FHFI];DTXCID0029397;Sodium citrate hydrate (JP17);UNII-B22547B95K;CHEBI:32142;Trisodium citrate dihydrate, ACS;SODIUM CITRATE HYDROUS [II];SODIUM CITRATE HYDRATE [JAN];SODIUM CITRATE [EP MONOGRAPH];SODIUM CITRATE DIHYDRATE [MI];AKOS025293920;Citronensaeure,Trinatrium-Salz-Dihydrat
;Sodium citrate dihydrate, >=99%, FG;SODIUM CITRATE DIHYDRATE [VANDF];BP-31019;SODIUM CITRATE DIHYDRATE [WHO-DD];Sodium citrate tribasic dihydrate, >=98%;Sodium citrate dihydrate, ACS reagent grade;SODIUM CITRATE, DIHYDRATE [WHO-IP];NS00074299;D01781;F82065;Sodium citrate tribasic dihydrate, AR, >=99%;Sodium citrate tribasic dihydrate, LR, >=99%;Citric acid trisodium salt dihydrate ACS reagent;NATRII CITRAS, DEHYDRATE [WHO-IP LATIN];A833161;A835986;Q22075862;Sodium citrate dihydrate Biochemical grade, Fine Granular;Sodium citrate tribasic dihydrate, USP, 99.0-100.5%;Sodium Citrate Tribasic Dihydrate (Molecular Biology Grade);Sodium citrate tribasic dihydrate, ACS reagent, >=99.0%;trisodium 2-oxidanylpropane-1,2,3-tricarboxylate dihydrate;Sodium citrate tribasic dihydrate, BioUltra, >=99.0% (NT);Sodium citrate tribasic dihydrate, insect cell culture tested;Sodium citrate tribasic dihydrate, JIS special grade, >=99.0%;Sodium citrate tribasic dihydrate, p.a., ACS reagent, 99.0%;Sodium citrate tribasic dihydrate, purum p.a., >=99.0% (NT);Sodium citrate tribasic dihydrate, SAJ first grade, >=99.0%;Sodium citrate tribasic dihydrate, tested according to Ph.Eur.;trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2);Trisodium citrate dihydrate, meets USP testing specifications;2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate;Sodium citrate tribasic dihydrate, BioXtra, >=99.0% (titration);Sodium citrate tribasic dihydrate, for molecular biology, >=99%;Sodium citrate tribasic dihydrate, Vetec(TM) reagent grade, 98%;Sodium citrate, United States Pharmacopeia (USP) Reference Standard;1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, dihydrate;Sodium citrate tribasic dihydrate, p.a., ACS reagent, reag. ISO, 99-101%;1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2);Sodium citrate tribasic dihydrate, BioUltra, for molecular biology, >=99.5% (NT);Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, >=99.0% (NT);Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=99.0%;Sodium Citrate, Pharmaceutical Secondary Standard; Certified Reference Material;Sodium citrate tribasicdihydrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%;Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=98% (titration), powder

Trisodium citrate (TSC) is the sodium salt of citric acid.
Trisodium citrate (TSC) is widely used as a preservative or for flavour.
Trisodium citrate (TSC) is also used in dietary supplements.
Trisodium citrate (TSC) is also an essential ingredient in dishwasher tablets, industrial cleaners, detergents, etc.
Trisodium citrate (TSC) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; it is odorless, salty taste, and cool.
Trisodium citrate (TSC) will lose its crystal water at 150 °C and will be decomposed at even higher temperature.
Trisodium citrate (TSC) also has slight deliquescence in wet air and has weathering property upon hot air.
Trisodium citrate (TSC) is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents.
Trisodium citrate (TSC) has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry.

Trisodium citrate (TSC) has the greatest demand when being used as a food additive; As food additives, it is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives; in addition, combination between sodium citrate and citric acid can be used in a variety of jams, jelly, juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements.
The dihydrate of Trisodium citrate (TSC).
Trisodium citrate (TSC) is the tribasic dihydrate sodium salt of citric acid.
Trisodium citrate (TSC) has the molecular formula Na3C6H5O7.
Trisodium citrate (TSC) is sometimes referred to simply as "sodium citrate", though sodium citrate can refer to any of the three sodium salts of citric acid.
Trisodium citrate (TSC) possesses a saline, mildly tart flavor, and is a mild alkali.

Trisodium citrate (TSC) is a tribasic salt of citric acid.
Trisodium citrate (TSC) is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.
Trisodium citrate (TSC) is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.
Trisodium citrate (TSC) occurs as white, granular crystals or as white, crystalline powder with a pleasant, salty taste.
Trisodium citrate (TSC) is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96 %).
Trisodium citrate (TSC) is a non-toxic, neutral salt with low reactivity.
Trisodium citrate (TSC) is chemically stable if stored at ambient temperatures.
Trisodium citrate (TSC) is fully biodegradable and can be disposed of with regular waste or sewage.

Trisodium citrate (TSC) Chemical Properties
Melting point: >300 °C(lit.)
Density: 1.76
FEMA: 3026 | SODIUM CITRATE
Fp: 173.9 °C
Storage temp.: Store at +5°C to +30°C.
Solubility H2O: 100 mg/mL
Form: powder
Color: white
PH: 7.0-9.0 (25℃, 50mg/mL in H2O)
Odor: Odorless
PH Range: 7.5 - 9 at 29.4 g/l at 25 °C
Water Solubility: 720 g/L (25 ºC)
λmax λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,8602
BRN: 6104939
Stability: Stable. Incompatible with bases, reducing agents, oxidizing agents.
InChIKey: NLJMYIDDQXHKNR-UHFFFAOYSA-K
LogP: -1.72
CAS DataBase Reference: 6132-04-3(CAS DataBase Reference)
EPA Substance Registry System: Trisodium citrate (TSC) (6132-04-3)

Trisodium citrate (TSC) is colorless crystals or white crystalline powder, and is odorless, cool and salty.
Trisodium citrate (TSC) has no melting point with a relative density of 1.857.
Trisodium citrate (TSC) is stable in air at room temperature with loss of crystal water when being heated to 150 °C loss of crystal water; further heating will cause its decomposition.
Trisodium citrate (TSC) is insoluble in ethanol but highly soluble in water. 5% aqueous solution has a pH value of 7.6 to 8.6.
Trisodium citrate (TSC) consists of odorless, colorless, monoclinic crystals, or a white crystalline powder with a cooling, saline taste.
Trisodium citrate (TSC) is slightly deliquescent in moist air, and in warm dry air it is efflorescent.
Although most pharmacopeias specify that Trisodium citrate (TSC) is the dihydrate, the USP 32 states that sodium citrate may be either the dihydrate or anhydrous material.

Uses
Trisodium citrate (TSC) can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour; Trisodium citrate (TSC) also has effects on forming complex with metal ions.
China rules that Trisodium citrate (TSC) can be applied to various types of food with appropriate usage according to the absolute necessity.
Trisodium citrate (TSC) can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry, it is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry.
Trisodium citrate (TSC) is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium; moreover, it can also be applied into pharmaceutical industry.

Trisodium citrate (TSC) can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry, it is used as anti-clotting agent, phlegm drugs and diuretics drugs.
Trisodium citrate (TSC) can also be used in brewing, injection, newspaper and movies medicines.
Anticoagulant for collection of blood.
In photography; as sequestering agent to remove trace metals; as emulsifier, acidulant and sequestrant in foods.
An anticoagulant also used as a biological buffer
Trisodium citrate (TSC), is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium citrate (TSC) used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.
Trisodium citrate (TSC) is chiefly used as a food additive, usually for flavor or as a preservative.

Foods
Trisodium citrate (TSC) is chiefly used as a food additive, usually for flavor or as a preservative.
Trisodium citrate (TSC) 2s E number is E331.
Trisodium citrate (TSC) is employed as a flavoring agent in certain varieties of club soda.
Trisodium citrate (TSC) is common as an ingredient in bratwurst, and is also used in commercial ready-to-drink beverages and drink mixes, contributing a tart flavor.
Trisodium citrate (TSC) is found in gelatin mix, ice cream, yogurt, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine, amongst others.
Trisodium citrate (TSC) can be used as an emulsifying stabilizer when making cheese.
Trisodium citrate (TSC) allows the cheese to melt without becoming greasy by stopping the fats from separating.

Buffering
As a conjugate base of a weak acid, citrate can perform as a buffering agent or acidity regulator, resisting changes in pH.
Trisodium citrate (TSC) is used to control acidity in some substances, such as gelatin desserts.
Trisodium citrate (TSC) can be found in the milk minicontainers used with coffee machines.
Trisodium citrate (TSC) is the product of antacids, such as Alka-Seltzer, when they are dissolved in water.
The pH range of a solution of 5 g/100 ml water at 25 °C is 7.5 to 9.0.
Trisodium citrate (TSC) is added to many commercially packaged dairy products to control the pH impact of the gastrointestinal system of humans, mainly in processed products such as cheese and yogurt, although Trisodium citrate (TSC) also has beneficial effects on the physical gel microstructure.

Chemistry
Trisodium citrate (TSC) is a component in Benedict's qualitative solution, often used in organic analysis to detect the presence of reducing sugars such as glucose.

Medicine
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used sodium citrate as an anticoagulant in blood transfusions, with Richard Lewisohn determining its correct concentration in 1915.
Trisodium citrate (TSC) continues to be used today in blood-collection tubes and for the preservation of blood in blood banks.
The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism.
Recently, Trisodium citrate (TSC) has also been used as a locking agent in vascath and haemodialysis lines instead of heparin due to its lower risk of systemic anticoagulation.

In 2003, Ööpik et al. showed the use of Trisodium citrate (TSC) improved running performance over 5 km by 30 seconds.
Trisodium citrate (TSC) is used to relieve discomfort in urinary-tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative.
Trisodium citrate (TSC) is a major component of the WHO oral rehydration solution.
Trisodium citrate (TSC) is used as an antacid, especially prior to anaesthesia, for caesarian section procedures to reduce the risks associated with the aspiration of gastric contents.

Boiler descaling
Trisodium citrate (TSC) is a particularly effective agent for removal of carbonate scale from boilers without removing them from operation and for cleaning automobile radiators.

Pharmaceutical Applications
Trisodium citrate (TSC), as either the dihydrate or anhydrous material, is widely used in pharmaceutical formulations.
Trisodium citrate (TSC) is used in food products, primarily to adjust the pH of solutions.
Trisodium citrate (TSC) is also used as a sequestering agent.
The anhydrous material is used in effervescent tablet formulations.
Trisodium citrate (TSC) is additionally used as a blood anticoagulant either alone or in combination with other citrates such as disodium hydrogen citrate.
Therapeutically, Trisodium citrate (TSC) is used to relieve the painful irritation caused by cystitis, and also to treat dehydration and acidosis due to diarrhea.

Excellent performance
Trisodium citrate (TSC) is currently the most important citrate.
Trisodium citrate (TSC) is produced by two steps: first starch food is fermented to generate citric acid; secondly, citric acid is neutralized by alkali to generate the final products.
Sodium citrate has the following excellent performance:
Safe and nontoxic properties; Since the basic raw material for the preparation of sodium citrate mainly comes from the food, Trisodium citrate (TSC) is absolutely safe and reliable without causing harm to human health.
The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that this product can be considered as non-toxic food.
Trisodium citrate (TSC) is biodegradable.
After subjecting to the dilution of a large amount of water, sodium citrate is partially converted into citrate, which coexists with sodium citrate in the same system.
Trisodium citrate (TSC) is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes.

Trisodium citrate (TSC)'s decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water.
The ability of forming complex with metal ions.
Trisodium citrate (TSC) has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, Trisodium citrate (TSC) also has a good complex-forming ability.
Excellent solubility, and the solubility increases with increasing temperature of water.
Trisodium citrate (TSC) has a good capability for pH adjustment and a good buffering property.
Sodium citrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which it is not suitable to have large change of pH value.
In addition, Trisodium citrate (TSC) also has excellent retardation performance and stability.

Effect and application
During the process of clinically taking fresh blood, adding some amount of sterile Trisodium citrate (TSC) can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion; In the field of medicine, Trisodium citrate (TSC) is used for the in vitro anti-clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions; it can also used for cyanide-free electroplating industry; also used as developer for photographic industry.
Trisodium citrate (TSC) can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry.
Moreover, Trisodium citrate (TSC) is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application.
Trisodium citrate (TSC) has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions; it is biodegradable and has a strong dispersing ability and anti-redeposition ability; Daily-applied chemical detergents use it as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent.
Adding a certain amount Trisodium citrate (TSC) to the detergent can significantly increase the cleaning ability of detergent cleaning.
The large scale of application of Trisodium citrate (TSC) as a builder in detergents is an important discovery in synthetic detergent industry.
Trisodium citrate (TSC) is non-toxic without environmental pollution; it can also be acted as a buffer for the production of cosmetics.

Production methods
Trisodium citrate (TSC) is produced by the neutralization of citric acid by sodium hydroxide or sodium bicarbonate.
Dissolve sodium bicarbonate in water upon stirring and heating; add citric acid, continue to heat up to 85-90 °C; adjust the pH to 6.8; adjust active carbon for bleaching.
Filter when the mixture is still hot; condense the filtrate under reduced pressure; cool and the crystal comes out; filter, wash, dry to obtain the final products of sodium citrate.
C6H8O7 + 3NaHCO3 → C6H5Na3O7 • 2H2O + 3CO2 ↑ + H2O

Production Methods
Trisodium citrate (TSC) is prepared by adding sodium carbonate to a solution of citric acid until effervescence ceases.
The resulting solution is filtered and evaporated to dryness.

Biochem/physiol Actions
Trisodium citrate (TSC) can act as a buffering agent, resisting changes in pH.
Used in blood collection tubes, the citrate chelates calcium ions in blood and thereby disrupts blood clotting.
Citrate is a intermediate in the TCA cycle and fatty acid synthesis.
Trisodium citrate (TSC) is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.

Trisodium Citrate Dihydrate is a white, crystalline powder with a slightly salty, sour taste.
Trisodium Citrate Dihydrate is a tribasic salt of citric acid.


CAS Number: 6132-04-3
EC Number: 200-675-3
MDL number: MFCD00150031
Molecular Formula: C6H9Na3O9


Trisodium Citrate Dihydrate is the trisodium salt of citric acid.
Trisodium Citrate Dihydrate is a crystalline white powder that is slightly deliquescent in moist air, freely soluble in water, and practically insoluble in alcohol.


Trisodium Citrate Dihydrate is a non-toxic, neutral salt with low reactivity.
Trisodium Citrate Dihydrate is a versatile chemical substance used in a variety of applications in different industries.
Trisodium Citrate Dihydrate is a white, crystalline powder with a slightly salty, sour taste.


Trisodium Citrate Dihydrate is a white odorless chemical used as a food additive.
Trisodium Citrate Dihydrate occurs as white, granular crystals or as white, crystalline powder with a pleasant, salty taste.
Trisodium Citrate Dihydrate is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96 %).


Trisodium Citrate Dihydrate is a non-toxic, neutral salt with low reactivity.
Trisodium Citrate Dihydrate is chemically stable if stored at ambient temperatures.
Trisodium Citrate Dihydrate is fully biodegradable and can be disposed of with regular waste or sewage.


Trisodium Citrate Dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.


Citric acid is the product of a microbial fermentation using carbohydrate substrates.
Trisodium Citrate Dihydrate is widely used as an excellent pH regulator and odourless buffering agent for bath and shower gels, creams, styling or decorative products.


Trisodium Citrate Dihydrate is both ECOCERT and COSMOS approved.
Trisodium Citrate Dihydrate is for the preparation of total ribosomal RNA from E. coli
Trisodium Citrate Dihydrate is a tribasic salt of citric acid.


Trisodium Citrate Dihydrate is produced by complete neutralization of citric acid with high purity sodium source and subsequent crystallization.
Trisodium Citrate Dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.


Trisodium Citrate Dihydrate has a sour taste similar to citric acid, and is salty as well.
Trisodium Citrate Dihydrate, (molecular formula: Na3C6H5O7 • 2H2O) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; it is odorless, salty taste, and cool.


Trisodium Citrate Dihydrate will lose its crystal water at 150 °C and will be decomposed at even higher temperature.
Trisodium Citrate Dihydrate also has slight deliquescence in wet air and has weathering property upon hot air.
Trisodium Citrate Dihydrate is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents.


Trisodium Citrate Dihydrate is manufactured by neutralizing citric acid derived from a submerged fermentation process.
Trisodium Citrate Dihydrate is produced in accordance with current Good Manufacturing Practices (GMP’s) under a comprehensive HACCP (Hazard Analysis and Critical Control Points) program.


Trisodium Citrate Dihydrate is considered “GRAS” (Generally
Recognized As Safe) by the United States Food and Drug Administration without restriction as to the quantity of use within good manufacturing practice.
Trisodium Citrate Dihydrate is also considered by the Experts Committee of the FAO/WHO to be a safe food additive without limitation according to good manufacturing practice.


Trisodium Citrate Dihydrate is a stable material.
Trisodium Citrate Dihydrate is manufactured to meet the monograph specifications of major world codex and pharmacopoeia standards including the USP, FCC, BP, EP, FAO/WHO and is certified Kosher Pareve, Kosher for Passover, and Halal.


Trisodium Citrate Dihydrate is available as translucent white crystals and has a slight saline taste.
Water of crystallization constitutes approximately twelve percent by weight of the dihydrate form.
Trisodium Citrate Dihydrate is a white powder or colourless crystals.


Trisodium Citrate Dihydrate is the dihydrate of trisodium citrate.
Trisodium Citrate Dihydrate is the tribasic dihydrate sodium salt of citric acid.
Trisodium Citrate Dihydrate (C6H5Na3O7.2H2O) is a tribasic salt of citric acid.


Trisodium Citrate Dihydrate is a urine alkalinizing agent.
After absorption Trisodium Citrate Dihydrate is metabolized to produce bicarbonate.
Trisodium Citrate Dihydrate is a white crystalline powder that is composed of sodium salt of citric acid.


Trisodium Citrate Dihydrate is highly soluble in water and has a sour taste.
Trisodium Citrate Dihydrate (E331) is the sodium salt of citric acid.
Like citric acid, Trisodium Citrate Dihydrate has a sour taste.


Like other salts, Trisodium Citrate Dihydrate also has a salty taste.
Trisodium Citrate Dihydrate gives club soda both its sour and salty flavors.
Trisodium Citrate Dihydrate reduces the acidity of foods, so it allows spherification with strongly acidic ingredients.


Trisodium Citrate Dihydrate is also used as an antioxidant in food as well as a sequestrant.
Trisodium Citrate Dihydrate dissolves easily and acts instantaneously.
Trisodium Citrate Dihydrate is odorless with a slightly saline taste.


Trisodium Citrate Dihydrate is sodium salt of citrate which has an alkalinizing activity with the chemical name Trisodium Citrate Dihydrate.
Trisodium Citrate Dihydrate is also called TriTrisodium Citrate Dihydrate or Citrosodine or Natrocitral.
Trisodium Citrate Dihydrate (C6H5Na3O7•2H2O, CAS Reg. No. 68–0904–092) is the sodium salt of citric acid.


Trisodium Citrate Dihydrate is prepared by neutralizing citric acid with sodium hydroxide or sodium carbonate.
Trisodium Citrate Dihydrate occurs as colorless crystals or a white crystalline powder.
Trisodium Citrate Dihydrate may be prepared in an anhydrous state or may contain two moles of water per mole of Trisodium Citrate Dihydrate.


Trisodium Citrate Dihydrate is the sodium salt of Citric Acid.
Like Citric acid, Trisodium Citrate Dihydrate has a sour taste.
Like other salts, Trisodium Citrate Dihydrate also has a salty taste.


Trisodium Citrate Dihydrate is commonly known as sour salt and is mainly used as a food additive, usually for flavor or as a preservative.
Trisodium Citrate Dihydrate gives club soda both its salty and sour flavors.
Trisodium Citrate Dihydrate reduces the acidity of foods, so it allows spherification with strongly acidic ingredients.


Trisodium Citrate Dihydrate is also used as an antioxidant in food as well as a sequestrant.
Trisodium Citrate Dihydrate dissolves easily and acts instantaneously.
Trisodium Citrate Dihydrate and citric acid combine in an oral solution to prevent kidney stones and metabolic acidosis.


This solution works by making your blood and pee less acidic.
You can mix this solution with 6 ounces of water before drinking it as directed.


Trisodium Citrate Dihydrate may refer to any of the sodium salts of citric acid (though most commonly the third):
*MonoTrisodium Citrate Dihydrate
*DiTrisodium Citrate Dihydrate
*TriTrisodium Citrate Dihydrate


The three forms of salt are collectively known by the E number E331.
Trisodium Citrate Dihydrate is the trisodium salt of citric acid.
Trisodium Citrate Dihydrate has a role as a flavouring agent and an anticoagulant.


Trisodium Citrate Dihydrate contains a citrate(3-).
Trisodium Citrate Dihydrate is the sodium salt of citric acid.
Trisodium Citrate Dihydrate is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol.


Like citric acid, Trisodium Citrate Dihydrate has a sour taste.
From the medical point of view, Trisodium Citrate Dihydrate is used as alkalinizing agent.
Trisodium Citrate Dihydrate works by neutralizing excess acid in the blood and urine.


Upon absorption, Trisodium Citrate Dihydrate dissociates into sodium cations and citrate anions; organic citrate ions are metabolized to bicarbonate ions, resulting in an increase in the plasma bicarbonate concentration, the buffering of excess hydrogen ion, the raising of blood pH, and potentially the reversal of acidosis.


In addition, increases in free sodium load due to Trisodium Citrate Dihydrate administration may increase intravascular blood volume, facilitating the excretion of bicarbonate compounds and an anti-urolithic effect.
Sodium salts of citric acid are used as buffers and food preservatives.


They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.
Trisodium Citrate Dihydrate increases the strong ion differenceSID=(Na++K++Ca2++Mg2+)−(Cl−+lactate−)provided that citrate is metabolized (Stewart concept).
TriTrisodium Citrate Dihydrate is often referred to as Trisodium Citrate Dihydrate, though Trisodium Citrate Dihydrate can refer to any of the three sodium salts of citric acid.


Trisodium Citrate Dihydrate has a saline, mildly tart flavor.
The Cosmetics Ingredient Review panel has deemed Trisodium Citrate Dihydrate safe as used in skin care products.
Trisodium Citrate Dihydrate serves as a preservative to ensure safe and durable products by inhibiting microbial growth.


Trisodium Citrate Dihydrate also assists in the regulation of pH of cosmetic formulations.
Trisodium Citrate Dihydrate refers to sodium salts of citric acid.
MonoTrisodium Citrate Dihydrate, diTrisodium Citrate Dihydrate, and triTrisodium Citrate Dihydrate are the three types of sodium salts of citric acid.


The three types of salts get collectively known as E number E 331.
However, Trisodium Citrate Dihydrate mostly refers to the third type, that is, triTrisodium Citrate Dihydrate.
Trisodium Citrate Dihydrate is a compound obtained after the alkalizing activity, and it’s a sodium salt of citrate.


Trisodium Citrate Dihydrate's chemical formula is Na3C6H5O7.
Trisodium Citrate Dihydrate is a sodium salt of citrate, and it has an alkalinizing activity.
Trisodium Citrate Dihydrate is also Known as TriTrisodium Citrate Dihydrate.


The sodium salts of citric acid are known as Trisodium Citrate Dihydrates.
There are three sodium salts of citric acid types: monoTrisodium Citrate Dihydrate, diTrisodium Citrate Dihydrate, and triTrisodium Citrate Dihydrate.
E number 331 (E331) refers to all three types of salts combined.


Trisodium Citrate Dihydrate has the chemical formula Na3C6H5O7.
Trisodium Citrate Dihydrate possesses a saline, mildly tart flavor, and is a mild alkali.
Trisodium Citrate Dihydrate has been indicated for the treatment of metabolic acidosis.


Trisodium Citrate Dihydrate is the sodium salt of citrate with alkalinizing activity.
Trisodium Citrate Dihydrate is a sodium salt of citrate obtained after the alkalizing activity, and its chemical formula is Na3C6H507.
On the other hand, Trisodium Citrate Dihydrate refers to a third type: triTrisodium Citrate Dihydrate.



USES and APPLICATIONS of TRISODIUM CITRATE DIHYDRATE:
In the cleaning industry Trisodium Citrate Dihydrate is commonly used because of its excellent cleaning characteristics and its unusual property of being almost neutral yet portraying the characteristics of an acid as in descalers and an alkali as in degreasers.
Cleaning products include laundry powders and detergents, toilet cleaners, hard surface cleaners, carpet cleaners, dish washing liquids, powder and liquid degreasers and pre-soaks.


Trisodium Citrate Dihydrate is becoming more and more popular now as it is considered environmentally friendly, it substitutes phosphates and is readily biodegradable.
In industry Trisodium Citrate Dihydrate finds many uses including alkaline degreaser baths, electroplating chemicals for copper and nickel etc, photo chemicals.


Trisodium Citrate Dihydrate is also used in the paper and pulp industries and the textiles industry.
Cosmetics and personal care uses of Trisodium Citrate Dihydrate: In cosmetics and personal care products, trisodium citrate is used as a buffering agent to maintain the pH of formulations and as a preservative to prevent microbial growth.


Cleaning products uses of Trisodium Citrate Dihydrate: Trisodium Citrate Dihydrate is used in some cleaning products, particularly in eco-friendly and biodegradable formulations, due to its ability to soften water, remove soap scum, and dissolve scale deposits.
Trisodium Citrate Dihydrate is typically used as a flavoring agent or as a preservative.


Trisodium Citrate Dihydrate is used as a plaster retardant.
The common hydrate form, Trisodium Citrate Dihydrate, is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.


Trisodium Citrate Dihydrate is used as a food additive and flavouring agent, this product possesses a saline, mildly tart flavour that can help in water sensitive formulations like instant drinks as well as tablets and powders in pharmaceuticals and detergents.
In the food industry, Trisodium Citrate Dihydrate is used as a flavor enhancer, acidity regulator, and emulsifier.


In the medical field, Trisodium Citrate Dihydrate is used as an anticoagulant but it is also an ingredient in many personal care products.
Trisodium Citrate Dihydrate is also an essential ingredient in dishwasher tablets, industrial cleaners, detergents, etc.
Trisodium Citrate Dihydrate is typically used as a buffer component in biomolecule downstream processing and liquid formulation.


Trisodium Citrate Dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.
Trisodium Citrate Dihydrate has a variety of applications in different industries due to its properties as a buffering agent, sequestrant, and emulsifying agent.


Trisodium Citrate Dihydrate is a high quality pharmaceutical excipient, offered with extensive documentation facilitating compliance, full supply chain transparency and risk mitigation.
Trisodium Citrate Dihydrate is the dihydrate of trisodium citrate.


Trisodium Citrate Dihydrate has a role as an anticoagulant.
Trisodium Citrate Dihydrate contains a sodium citrate.
Trisodium Citrate Dihydrate is often used as a food preservative, and as a flavoring in the food industry.


In the pharmaceutical industry, Trisodium Citrate Dihydrate is used to control pH.
Trisodium Citrate Dihydrate may be used as an alkalizing agent, buffering agent, emulsifier, or sequestering agent.
Sodium salts of citric acid are used as buffers and food preservatives.


They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.
Trisodium Citrate Dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.
Buffers pH and enhances action of methyl parabens.


Trisodium Citrate Dihydrate is used in toothpastes & dental creams, effervescent denture cleansers, mouth rinses and oral hygiene products.
Trisodium Citrate Dihydrate is used as a substrate for citrate lyase, a buffer component; an anticoagulant.
For anticoagulation use Trisodium Citrate Dihydrate is typically used at a concentration of approximately 0.129 M (i.e. for 4.5 mL blood use 16.0 mg sodium citrate and 2.1 mg citric acid).


Trisodium Citrate Dihydrate is used preparation of sodium citrate buffer for antigen unmasking in IHC.
Trisodium Citrate Dihydrate has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry.


Trisodium Citrate Dihydrate has the greatest demand when being used as a food additive.
As food additives, Trisodium Citrate Dihydrate is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives.
In addition, combination between Trisodium Citrate Dihydrate and citric acid can be used in a variety of jams, jelly, juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements.


Trisodium Citrate Dihydrate is used as a substrate for citrate lyase, a buffer component; an anticoagulant.
For anticoagulation use Trisodium Citrate Dihydrate is typically used at a concentration of approximately 0.129 M (i.e. for 4.5 mL blood use 16.0 mg sodium citrate and 2.1 mg citric acid).


Trisodium Citrate Dihydrate is a source of Citric acid, a key metabolic intermediate.
Citrate is the starting point of the tricarboxylic acid cycle.
Trisodium Citrate Dihydrate's concentration also coordinates several other metabolic pathways.
Citric acid can form complexes with various cations, particularly with iron and calcium.


In animals, citric acid improves the utilization of nutritional calcium.
Trisodium Citrate Dihydrate is also known as Sodium Citrate which is a sodium salt from citric acid.
Trisodium Citrate Dihydrate is used in food products as a preservative as well as to add a tart flavor profile.


Trisodium Citrate Dihydrate is commonly used as a flavoring agent in drinks as well as processed cheese, ice cream, yogurt and jams.
As an ingredient in personal care products, Trisodium Citrate Dihydrate is used in cosmetics and other skin care products primarily to control the pH level, as well as for its preservative properties.


As an ingredient in supplements, Trisodium Citrate Dihydrate helps control pH in the kidneys helping to prevent gout and certain types of kidney stones.
In this application Trisodium Citrate Dihydrate is normally combined with Citric Acid.
Trisodium Citrate Dihydrate is a useful reactant in organic synthesis.


Trisodium Citrate Dihydrate is used as a flavouring agent and an anticoagulant.
Moreover, Trisodium Citrate Dihydrate is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application.


Trisodium Citrate Dihydrate has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions.
Trisodium Citrate Dihydrate is biodegradable and has a strong dispersing ability and anti-redeposition ability.
Daily-applied chemical detergents use Trisodium Citrate Dihydrate as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent.


Adding a certain amount Trisodium Citrate Dihydrate to the detergent can significantly increase the cleaning ability of detergent cleaning.
The large scale of application of Trisodium Citrate Dihydrate as a builder in detergents is an important discovery in synthetic detergent industry.
Trisodium Citrate Dihydrate is non-toxic without environmental pollution.


Trisodium Citrate Dihydrate can also act as a buffer for the production of cosmetics.
Trisodium Citrate Dihydrate can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour.


Trisodium Citrate Dihydrate also has effects on forming complex with metal ions.
China rules that Trisodium Citrate Dihydrate can be applied to various types of food with appropriate usage according to the absolute necessity.
Trisodium Citrate Dihydrate can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry.


Trisodium Citrate Dihydrate is used for the manufacturing of anti-clotting drugs, and used as the detergent additives in light industry.
Trisodium Citrate Dihydrate is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium.
Moreover, Trisodium Citrate Dihydrate can also be applied into pharmaceutical industry.


Trisodium Citrate Dihydrate can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry.
At pharmaceutical industry, Trisodium Citrate Dihydrate is used as anti-clotting agent, phlegm drugs and diuretics drugs.


Trisodium Citrate Dihydrate can also be used in brewing, injection, newspaper and movies medicines.
Trisodium Citrate Dihydrate is chiefly used as a food additive, usually for flavor or as a preservative.
Trisodium Citrate Dihydrate is used as an anticoagulant for collection of blood.


In photography, Trisodium Citrate Dihydrate is used as a sequestering agent to remove trace metals
Trisodium Citrate Dihydrate is used as emulsifier, acidulant and sequestrant in foods.
Trisodium Citrate Dihydrate is used as an anticoagulant, also used as a biological buffer.


Food uses of Trisodium Citrate Dihydrate: Baby Food, Infant Formula, Bakery, Cereals, Snacks, Confectionery, Dairy, Dairy Alternatives, Desserts, Ice Cream, Flavours, Fruit Preparations, Sweet Spreads, Fruits, Vegetables, Meat Alternatives, Meat, Seafood, Plant-based Products, Ready Meals, Instant Food, Sauces, Dressings, Seasonings.


Trisodium Citrate Dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium Citrate Dihydrate used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.
Trisodium Citrate Dihydrate is commonly used laboratory reagent.


Healthcare uses of Trisodium Citrate Dihydrate: Clinical Nutrition, Medical Devices, OTC, Food Supplements, and Pharmaceutical Products
Personal Care uses of Trisodium Citrate Dihydrate: Colour Cosmetics, Fragrances, Hair Care, Oral Care, Skin Care,, and Soap and Bath Products
Cleaners & Detergents uses of Trisodium Citrate Dihydrate: Dish Washing, Industrial Cleaners, Laundry Care, and Surface Care.


Industrial Applications uses of Trisodium Citrate Dihydrate: Adhesives, Sealants, Agrochemicals, Fertilisers, Construction, Fine Chemicals, Inks, Paints, Coatings, Oil Drilling, Paper, Plastics, Polymers, Textile, and Leather.
Feed & Pet Food uses of Trisodium Citrate Dihydrate: Feed, and Pet Food


Pharma uses of Trisodium Citrate Dihydrate: Buffering agent, Chelating agent, Mineral source.
Beverages uses of Trisodium Citrate Dihydrate: Alcoholic Beverages, Carbonated Soft Drinks, Instant Drinks, Syrups, Juice Drinks, Plant-based, RTD Tea and Coffee, Sports and Energy Drinks, Waters.


Trisodium Citrate Dihydrate is also used as an emulsifier for oils in the cheesemaking process.
Trisodium Citrate Dihydrate allows cheese to melt without becoming greasy.
Historically, sodium phosphate was used to keep water and fat droplets mixed when cheese is melted.


Trisodium Citrate Dihydrate is used Soy Products Bakery Flavors.
Trisodium Citrate Dihydrate is used Table Top Product Dairy Confectionery.
Trisodium Citrate Dihydrate is used Fruits, Vegetables Meat, Seafood , Cereals, Snacks Desserts, Ice Cream Ready Meals, Instant Food.


Trisodium Citrate Dihydrate is used Fruit Preparations, Sweet Spreads Baby Food, Infant Formula.
Trisodium Citrate Dihydrate is used Sauces, Dressings, Seasoning.
Trisodium Citrate Dihydrate helps in enabling the melting of cheeses by not becoming greasy.


Trisodium Citrate Dihydrate is used in drinks and food as an acidity regulator.
Trisodium Citrate Dihydrate is used as an emulsifier for oils.
Trisodium Citrate Dihydrate is used as a pharmaceutical aid.


Trisodium Citrate Dihydrate is used as an anticoagulant for the blood.
Trisodium Citrate Dihydrate is used to prevent curdling of milk.
Trisodium Citrate Dihydrate is used as a food additive.


Trisodium Citrate Dihydrate is used to avoid clotting of fresh beef blood.
Trisodium Citrate Dihydrate is used in electroplating.
Trisodium Citrate Dihydrate is used Fruits & Vegetables: Jams & Jellies, Preserves, and Meat & Fish.


Trisodium Citrate Dihydrate has significant applications in food and beverage, healthcare, and other industries.
Trisodium Citrate Dihydrate usage is primarily done as an emulsifier in the production of dairy products such as cheese because it can keep a dairy product fresh for many days longer than other solutions.


Sodium citric acid is also a flavoring agent in many products such as milk powders, ice cream, wine, beverages, and jams.
Metabolic acidosis uses of Trisodium Citrate Dihydrate: Trisodium Citrate Dihydrate has applications for the treatment of metabolic acidosis and chronic kidney disease.
Ferrous nanoparticles uses of Trisodium Citrate Dihydrate: Along with oleic acid Trisodium Citrate Dihydrate may be used in the synthesis of magnetic Fe3O4 nanoparticle coatings.


Trisodium Citrate Dihydrate is used to relieve discomfort in urinary-tract infections, such as cystitis, to reduce the acidosis seen in distal renal tubular acidosis, and can also be used as an osmotic laxative.
Trisodium Citrate Dihydrate is a major component of the WHO oral rehydration solution.


Trisodium Citrate Dihydrate is used as an antacid, especially prior to anaesthesia, for caesarian section procedures to reduce the risks associated with the aspiration of gastric contents.
Trisodium Citrate Dihydrateprevents and treats high acid levels in your body.


Trisodium Citrate Dihydrate may also be used to help prevent gout or kidney stones, conditions caused by high uric acid levels.
Trisodium Citrate Dihydrate works by decreasing the amount of acid in your body.
Trisodium Citrate Dihydrate may be used for other purposes; ask your health care provider or pharmacist if you have questions.


Trisodium Citrate Dihydrate can be used to treat metabolic acidosis, where the generated bicarbonate buffers excess hydrogen ions in the blood, raising its p H.
Trisodium Citrate Dihydrate can also be used to alkalinize urine by promoting urinary excretion of free bicarbonate and therefore hydrogen ions.
Trisodium Citrate Dihydrate can be used to prevent development of renal stones that develop in acidic urine Fan et al, and in solution is administered as a bladder irritant during urological surgery.


Trisodium Citrate Dihydrate is administered rectally as an osmotic laxative.
Trisodium Citrate Dihydrate is a compound commonly used as an acidity regulator, an emulsifier, and a flavor enhancer in a wide range of food products and as a component of electrolyte solutions in medical settings.


Trisodium Citrate Dihydrate is also used as a sequestrant, which means it can bind to metal ions in food and prevent them from reacting with other ingredients.
Trisodium Citrate Dihydrate is also often used in cheese-making as a emulsifying salt, and as a coagulant in tofu production.
Trisodium Citrate Dihydrate is commonly added to soft drinks, ice cream, and other processed foods as a flavor enhancer and preservative.


Trisodium Citrate Dihydrate can also be used in medical applications, such as to prevent blood clots during surgery.
Trisodium Citrate Dihydrate is also used in cosmetic products, such as shampoos and body washes, as a pH regulator and as a chelating agent to prevent discoloration and maintain the stability of the product.


Trisodium Citrate Dihydrate is a salt of citric acid.
Use a small amount of Trisodium Citrate Dihydrate to make a melty cheese sauce out of any cheese.
Add to spherification liquids to neutralize the pH when needed


Commonly used as a sequestrant and pH buffer in food and beverages
Trisodium Citrate Dihydrate is widely used as a food preservative, for alkalization of urine to prevent kidney stones, as an anticoagulant for stored blood, and buffer.
Cosmetic manufacturers use Trisodium Citrate Dihydrate to adjust the acidity of a product.


Citrate, in the form of citric acid, is also found in citric fruits and juices.
Trisodium Citrate Dihydrate is used as a flavouring agent and an anticoagulant.
Trisodium Citrate Dihydrate is used to make urine less acidic and therefore prevent the formation of kidney stones.


Trisodium Citrate Dihydrate/citric acid also is useful as a buffer and neutralizing agent for gastric acid.
Trisodium Citrate Dihydrate is broken down to sodium bicarbonate which decreases the acidity of urine, increasing the excretion of substances that cause kidney stones.
Trisodium Citrate Dihydrate is commonly known as sour salt and is mainly used as a food additive, usually for flavor or as a preservative.


Trisodium Citrate Dihydrate has major applications in food and beverage, healthcare, and other industrial ones too.
Trisodium Citrate Dihydrate is used as a food additive, as a buffering agent and can also be used in medical applications.
Trisodium Citrate Dihydrate is used anticoagulant for collection of blood.


In photography; Trisodium Citrate Dihydrate is used as sequestering agent to remove trace metals.
Trisodium Citrate Dihydrate is used as emulsifier, acidulant and sequestrant in foods.
Trisodium Citrate Dihydrate is a useful and commonly used reagent.


Trisodium Citrate Dihydrate is the sodium salt of citric acid, it is commonly added to cosmetic and food preparations as a chelating and buffering agent.
Buffers help to maintain the pH of a product and keep it stable.
Trisodium Citrate Dihydrate also has mild antioxidant properties and can act as a co-preservative.


Trisodium Citrate Dihydrate is in the form of TriTrisodium Citrate Dihydrate Dihydrate.
Trisodium Citrate Dihydrate is intended for external use only.
Trisodium Citrate Dihydrate is a vital substance in the medicine and food industries.


Trisodium Citrate Dihydrate is a salt of citric acid, a natural organic acid found in citrus fruits, corn, and other foods.
Trisodium Citrate Dihydrate is available in colorless crystals or white powder.
This is typically sold as white, crystalline triTrisodium Citrate Dihydrate dihydrate.


As a food additive, Trisodium Citrate Dihydrate is widely used as a flavoring agent and a preservative in the food industry.
Flavoring agents like E331 are most commonly seen.
Trisodium Citrate Dihydrate is the sodium salt of citrate and is the compound formed after alkalinizing activity.


Citrate anions and sodium cations are formed upon absorption of Trisodium Citrate Dihydrate.
Trisodium Citrate Dihydrate is a sodium salt of citrate with alkalinizing properties.
TriTrisodium Citrate Dihydrate is another name for Trisodium Citrate Dihydrate.


Trisodium Citrate Dihydrate can be used as a food preservative, an anticoagulant for stored blood, and an alkalizing agent for urine to eliminate kidney stones.
The three types of Trisodium Citrate Dihydrate are monosodium, disodium, and triTrisodium Citrate Dihydrates.
Trisodium Citrate Dihydrate is mildly basic and can be used along with citric acid to make biologically compatible buffers.


Trisodium Citrate Dihydrate is primarily used as a food additive, usually for flavor or as a preservative.
In certain varieties of club soda, Trisodium Citrate Dihydrate is employed as a flavoring agent.
Trisodium Citrate Dihydrate is a common ingredient in Bratwurst, and is also used to contribute a tart flavor in commercial, ready-to- drink beverages and drink mixes.


Trisodium Citrate Dihydrate is found in gelatin mix, ice-cream, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine.
If used together with Trisodium Citrate Dihydrate, it is possible for citric acid to help maintain the flavor of other types of soft drinks without adding to the tanginess.


Trisodium Citrate Dihydrate can also provide a cool saline taste.
Trisodium Citrate Dihydrate is used Dish Washing Industrial Cleaners and Laundry Care Surface Care.
Trisodium Citrate Dihydrate acts as a buffering agent in cosmetics products to control their pH level.


Trisodium Citrate Dihydrate can also be used as a preservative.
Trisodium Citrate Dihydrate is used in various cosmetic products, including baby products, make-up, bath products, hair dyes and colors and skin care products.


Trisodium Citrate Dihydrate in skin care is used primarily to control the pH level of a product (such as in cleansers and exfoliants).
Trisodium Citrate Dihydrate is a salt of citric acid, which, as the name implies, can be derived from citrus fruits.
Because of its connection to citric acid, Trisodium Citrate Dihydrate also has antioxidant and mild, but limited, preservative properties.


Trisodium Citrate Dihydrate has several other useful applications, including its use as a chelating agent, which keeps metals in water from binding to other ingredients and impacting their efficacy.


Trisodium Citrate Dihydrate is supplied in crystal or powder form, and used at concentrations no higher than 12%.
Trisodium Citrate Dihydrate’s also a food additive used to keep food fresher longer and prevent melted cheese from becoming greasy.
In the medical field Trisodium Citrate Dihydrate is used to keep donated blood from clotting in storage.


A little helper ingredient, Trisodium Citrate Dihydrate is used to adjust the pH of the product.
Trisodium Citrate Dihydrate also helps to keep products stay nice longer by neutralizing the metal ions in the formula (they usually come from water).
Trisodium Citrate Dihydrate is widely used as a food preservative, anticoagulant for stored blood, and alkalization of urine to get rid of kidney stones.


Trisodium Citrate Dihydrate formula is Na3C6H5O7.
Trisodium Citrate Dihydrate gets majorly used in medicine as well as the food industry.


-Pharmaceutical industry uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is used as an anticoagulant in blood collection tubes, a buffering agent in various medications, and a urinary alkalizer to help treat certain kidney conditions.
Trisodium Citrate Dihydrate can also be used as an osmotic laxative to relieve constipation.


-Laboratory applications of Trisodium Citrate Dihydrate:
In the laboratory setting, Trisodium Citrate Dihydrate is commonly used as a buffer in molecular biology experiments, particularly in gel electrophoresis and DNA extraction procedures.
Trisodium Citrate Dihydrate helps maintain a stable pH and protects samples from degradation.



-Pharmacodynamics uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate prevents activation of the clotting cascade by chelating calcium ions.
Trisodium Citrate Dihydrate neutralizes acid in the stomach and urine, raising the pH 8.


-Food applications of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is used as acidity regulators in food and drinks, and also as emulsifiers for oils.
Trisodium Citrate Dihydrate enables cheeses to melt without becoming greasy.
Trisodium Citrate Dihydrate reduces the acidity of food as well.


-Blood clotting inhibitor uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is used to prevent donated blood from clotting in storage.
Trisodium Citrate Dihydrate is also used in a laboratory, before an operation, to determine whether a person's blood is too thick and might cause a blood clot, or if the blood is too thin to safely operate.
Trisodium Citrate Dihydrate is used in medical contexts as an alkalinizing agent in place of sodium bicarbonate, to neutralize excess acid in the blood and urine.


-Foods uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is chiefly used as a food additive, usually for flavor or as a preservative.
Trisodium Citrate Dihydrate's E number is E331.
Trisodium Citrate Dihydrate is employed as a flavoring agent in certain varieties of club soda.

Trisodium Citrate Dihydrate is common as an ingredient in bratwurst, and is also used in commercial ready-to-drink beverages and drink mixes, contributing a tart flavor.
Trisodium Citrate Dihydrate is found in gelatin mix, ice cream, yogurt, jams, sweets, milk powder, processed cheeses, carbonated beverages, and wine, amongst others.

Trisodium Citrate Dihydrate can be used as an emulsifying stabilizer when making cheese.
Trisodium Citrate Dihydrate allows the cheese to melt without becoming greasy by stopping the fats from separating.


-Buffering uses of Trisodium Citrate Dihydrate:
As a conjugate base of a weak acid, Trisodium Citrate Dihydrate can perform as a buffering agent or acidity regulator, resisting changes in pH.
Trisodium Citrate Dihydrate is used to control acidity in some substances, such as gelatin desserts.
Trisodium Citrate Dihydrate can be found in the milk minicontainers used with coffee machines.

Trisodium Citrate Dihydrate is the product of antacids, such as Alka-Seltzer, when they are dissolved in water.
The pH of a solution of 5 g/100 ml water at 25 °C is 7.5 – 9.0.
Trisodium Citrate Dihydrate is added to many commercially packaged dairy products to control the pH impact of the gastrointestinal system of humans, mainly in processed products such as cheese and yogurt, although Trisodium Citrate Dihydrate also has beneficial effects on the physical gel microstructure.


-Chemistry uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is a component in Benedict's qualitative solution, often used in organic analysis to detect the presence of reducing sugars such as glucose.


-Medicine uses of Trisodium Citrate Dihydrate:
In 1914, the Belgian doctor Albert Hustin and the Argentine physician and researcher Luis Agote successfully used Trisodium Citrate Dihydrate as an anticoagulant in blood transfusions, with Richard Lewisohn determining its correct concentration in 1915.
Trisodium Citrate Dihydrate continues to be used today in blood-collection tubes and for the preservation of blood in blood banks.

The citrate ion chelates calcium ions in the blood by forming calcium citrate complexes, disrupting the blood clotting mechanism.
Recently, triTrisodium Citrate Dihydrate has also been used as a locking agent in vascath and haemodialysis lines instead of heparin due to its lower risk of systemic anticoagulation.


-Boiler descaling uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is a particularly effective agent for removal of carbonate scale from boilers without removing them from operation and for cleaning automobile radiators.


-Food & Beverage uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate dihydrate is the most widely used emulsifying salt in sliced processed cheese products.
Trisodium Citrate Dihydrate is commonly used as a buffering agent in combination with citric acid to provide precise pH control required in many food and beverage applications.


-Food and Beverage uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is used as an emulsifying salt in processed cheese products.
The cheese may melt without getting greasy thanks to Trisodium Citrate Dihydrate.
When combined with citric acid, Trisodium Citrate Dihydrate acts as a buffering agent, allowing for precise pH regulation in various foods and beverages.

Trisodium Citrate Dihydrate prevents milk from curdling.
Trisodium Citrate Dihydrate is employed in the emulsification of oils.
Trisodium Citrate Dihydrate's primary purpose is to act as a food additive to enhance flavor or preserve food.


-Healthcare uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is an effective blood anticoagulant.
As a result, Trisodium Citrate Dihydrate is frequently used for blood collection and storage.
Trisodium Citrate Dihydrate can help to alleviate the discomfort associated with urinary tract infections.

Trisodium Citrate Dihydrate can also be used as a laxative to treat acidosis.
Trisodium Citrate Dihydrate’s essential to the World Health Organization’s oral rehydration solution.
Trisodium Citrate Dihydrate can also be used as an antacid, particularly before surgery.

Trisodium Citrate Dihydrate is found in many pharmaceuticals, colors, cosmetics, and deodorants.
Trisodium Citrate Dihydrate can be found in hair, oral, skin, and bathing products.
To treat excess acid in the stomach, Trisodium Citrate Dihydrate acts as a buffer and a neutralizing agent.
Trisodium Citrate Dihydrate is also used to treat metabolic acidosis, a type of renal problem that affects some people.


-Industrial Applications of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is used in industry as a cleaner.
Trisodium Citrate Dihydrate aids in the removal of calcium and rust layers from hot water systems and steam lines.
In electroplating processes, Trisodium Citrate Dihydrate also acts as a buffering and complexing agent.

Citric acid’s chelating ability and non-toxicity benefit the textile and building industries.
To avoid microbial contamination, Trisodium Citrate Dihydrate is used as a flavoring and preservative (i.e. as a food additive).
Trisodium Citrate Dihydrate is used as an oil emulsifier in cheese production.

Trisodium Citrate Dihydrate is a buffering agent in cosmetics to keep the pH stable.
Trisodium Citrate Dihydrate is used in soft and refreshing drinks to reduce sourness and enhance flavor.
Trisodium Citrate Dihydrate is found in dishwashing detergents, laundry detergents, and surface-active agents.


-Food and Beverage uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate gets used as an emulsifying salt in processed cheese products.
Trisodium Citrate Dihydrate facilitates the melting of cheese without becoming greasy.

Trisodium Citrate Dihydrate works as a buffering agent in combination with citric acid, and it offers accurate pH control necessary for numerous foods and beverages.
Trisodium Citrate Dihydrate's main job is being a food additive, either for flavor to improve taste or preservation purposes.


-Healthcare uses of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate works perfectly as an anticoagulant for the blood.
Thus, Trisodium Citrate Dihydrate gets widely used for blood collection and storage purposes.

Trisodium Citrate Dihydrate can provide relief from the discomfort in urinary tract infections.
Trisodium Citrate Dihydrate is also a great laxative and reduces several acidosis issues.
Trisodium Citrate Dihydrate’s a significant ingredient of WHO’s oral rehydration solution.

Trisodium Citrate Dihydrate also serves as an antacid, especially before anaesthesia.
You can easily find Trisodium Citrate Dihydrate in many pharmaceutical products, colour, cosmetics, and deodorants.
Trisodium Citrate Dihydrate’s also present in hair care, oral care, skincare, and bathing products.


-Industrial Applications of Trisodium Citrate Dihydrate:
Trisodium Citrate Dihydrate is used as an industrial cleaner.
Trisodium Citrate Dihydrate helps with clearing steam blocks, hot water systems of calcium and rust layers.

Trisodium Citrate Dihydrate also serves as a buffering and complexing agent in electroplating processes.
Textile and building industry, Trisodium Citrate Dihydrate gets benefited by the chelating ability and non-toxicity of citric acid.



EFFECT AND APPLICATION OF TRISODIUM CITRATE DIHYDRATE:
During the process of clinically taking fresh blood, adding some amount of sterile sodium citrate can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion; In the field of medicine, Trisodium Citrate Dihydrate is used for the in vitro anti-clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions; it can also used for cyanide-free electroplating industry; also used as developer for photographic industry.
Trisodium Citrate Dihydrate can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry.



PHARMACEUTICAL APPLICATIONS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate, as either the dihydrate or anhydrous material, is widely used in pharmaceutical formulations.
Trisodium Citrate Dihydrate is used in food products, primarily to adjust the pH of solutions.
Trisodium Citrate Dihydrate is also used as a sequestering agent. The anhydrous material is used in effervescent tablet formulations. Trisodium Citrate

Dihydrate is additionally used as a blood anticoagulant either alone or in combination with other citrates such as disodium hydrogen citrate.
Therapeutically, Trisodium Citrate Dihydrate is used to relieve the painful irritation caused by cystitis, and also to treat dehydration and acidosis due to diarrhea.



CHEMICAL PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is colorless crystals or white crystalline powder, and is odorless, cool and salty.
Trisodium Citrate Dihydrate has no melting point with a relative density of 1.857.

Trisodium Citrate Dihydrate is stable in air at room temperature with loss of crystal water when being heated to 150 °C loss of crystal water; further heating will cause its decomposition.
Trisodium Citrate Dihydrate is insoluble in ethanol but highly soluble in water. 5% aqueous solution has a pH value of 7.6 to 8.6.



CHARACTERISTICS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is a White, granular crystals or a white, crystalline powder; slightly deliquescent (tending to absorb moisture from the air and dissolve in it) in moist air, is freely soluble in water, and practically insoluble in ethanol (96%).
Trisodium Citrate Dihydrate is practically odorless and is colorless in solution.



SPECIFICATIONS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is GRAS affirmed under 21 CFR 184.1751.
Trisodium Citrate Dihydrate meets all requirements of the U.S. Pharmacopoeia, Food Chemical Codex, Code of Federal Regulations and European Pharmacopoeia.
Trisodium Citrate Dihydrate goes by EC No. 200-675-3, E Number E331 and CAS No. 6132-04-3.
Trisodium Citrate Dihydrate is certified as Kosher.



EXCELLENT PERFORMANCE OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is currently the most important citrate.
Trisodium Citrate Dihydrate is produced by two steps: first starch food is fermented to generate citric acid; secondly, citric acid is neutralized by alkali to generate the final products.
Trisodium Citrate Dihydrate has the following excellent performance:



SAFE AND NONTOXIC PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
Since the basic raw material for the preparation of Trisodium Citrate Dihydrate mainly comes from the food, it is absolutely safe and reliable without causing harm to human health.
The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that Trisodium Citrate

Dihydrate can be considered as non-toxic food.
Trisodium Citrate Dihydrate is biodegradable.
After subjecting to the dilution of a large amount of water, Trisodium Citrate Dihydrate is partially converted into citrate, which coexists with Trisodium
Citrate Dihydrate in the same system.

Citrate is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes.
Trisodium Citrate Dihydrate's decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water.

The ability of forming complex with metal ions.
Trisodium Citrate Dihydrate has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, it also has a good complex-forming ability.
Excellent solubility, and the solubility increases with increasing temperature of water.

Trisodium Citrate Dihydrate has a good capability for pH adjustment and a good buffering property.
Trisodium Citrate Dihydrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which it is not suitable to have large change of pH value.
In addition, Trisodium Citrate Dihydrate also has excellent retardation performance and stability.



MAIN FUNCTIONS OF TRISODIUM CITRATE DIHYDRATE:
*pH regulator
*Chelating agent
*Buffering agent
*Flavour enhancer
*Stabiliser
*Emulsifying agent



PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
*Dihydrate
*White
*Granular crystals or crystalline powder
*Typical, practically odourless
*Pleasantly salty
*Freely soluble in water
*Practically insoluble in ethanol (96 %)
*Non-toxic
*Low reactive
*Chemically and microbiologically stable
*Fully biodegradable



PRODUCTION METHODS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is produced by the neutralization of citric acid by sodium hydroxide or sodium bicarbonate.
Dissolve sodium bicarbonate in water upon stirring and heating; add citric acid, continue to heat up to 85-90 °C; adjust the pH to 6.8; adjust active carbon for bleaching.

Filter when the mixture is still hot; condense the filtrate under reduced pressure; cool and the crystal comes out; filter, wash, dry to obtain the final products of sodium citrate.
C6H8O7 + 3NaHCO3 → C6H5Na3O7 • 2H2O + 3CO2 ↑ + H2O



CHEMICAL PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate consists of odorless, colorless, monoclinic crystals, or a white crystalline powder with a cooling, saline taste.
Trisodium Citrate Dihydrate is slightly deliquescent in moist air, and in warm dry air it is efflorescent.



PRODUCTION METHODS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is prepared by adding sodium carbonate to a solution of citric acid until effervescence ceases.
The resulting solution is filtered and evaporated to dryness.



FUNCTIONS OF TRISODIUM CITRATE DIHYDRATE:
*Sequestering Agent,
*Buffering Agent,
*Supplement,
*Stabilizer,
*Emulsifier



PURIFICATION METHODS OF TRISODIUM CITRATE DIHYDRATE:
Crystallise the salt from warm water by cooling to 0o.



INCOMPATIBILITIES OF TRISODIUM CITRATE DIHYDRATE:
Aqueous solutions are slightly alkaline and will react with acidic substances.
Alkaloidal salts may be precipitated from their aqueous or hydro-alcohol solutions.
Calcium and strontium salts will cause precipitation of the corresponding citrates.
Other incompatibilities include bases, reducing agents, and oxidizing agents.



BIOCHME/PHYSIOL ACTIONS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate can act as a buffering agent, resisting changes in pH.
Trisodium Citrate Dihydrate is used in blood collection tubes, the citrate chelates calcium ions in blood and thereby disrupts blood clotting.
Citrate is a intermediate in the TCA cycle and fatty acid synthesis.
Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.



USING TRISODIUM CITRATE DIHYDRATE TO RETARD PLASTER MIXES:
Trisodium Citrate Dihydrate, is sometimes used in plastering as a retarder or setting time regulator.
Plaster is made by mixing gypsum powder with water, and then the mixture is applied to a surface where it hardens as it dries
Trisodium Citrate Dihydrate can be added to the water used to mix the plaster to slow down the setting time of the mixture.

Trisodium Citrate Dihydrate can be useful in situations where more time is needed to work with the plaster or to apply it to a surface, as it prevents the plaster from setting too quickly.
The amount of Trisodium Citrate Dihydrate required to slow down the setting time of plaster can vary depending on the specific application and the desired outcome.

As a general guideline, a concentration of 0.2% to 0.5% of the weight of the gypsum in the plaster mixture is often used.
For example, if you are using 1 kilogram of gypsum powder to make your plaster mixture, you could add between 2 to 5 grams of Trisodium Citrate Dihydrate to the water used to mix the plaster.

However, it's important to note that adding too much Trisodium Citrate Dihydrate can weaken the strength of the plaster and affect its overall quality.
So, Trisodium Citrate Dihydrate's recommended to start with a small amount and gradually increase the concentration until you achieve the desired setting time without compromising the strength of the plaster.



SKIN CARE USES OF TRISODIUM CITRATE DIHYDRATE:
The pH of a product is established and maintained by Trisodium Citrate Dihydrate.
While the skin's normal pH is slightly acidic, typically between 4.75 and 5.5, which effectively protects the skin from environmental factors such as allergens, pollutants, and bacteria, Trisodium Citrate Dihydrate can buffer solutions in the pH range of about 3 to 6.2.

The skin's acidity can change as a result of everything that comes into contact with Trisodium Citrate Dihydrate, including cosmetics, the sun, water, pollution, etc.
This ultimately hinders the skin's capacity to defend itself.
In order to maintain the skin's normal pH as closely as possible, Trisodium Citrate Dihydrate is crucial to balance the pH of cosmetics and skincare products.

A highly acidic product may irritate the skin, and a highly alkaline one may decrease its lipid contents.
By using an ingredient like Trisodium Citrate Dihydrate, cosmetic manufacturers can adjust the pH of their formulations, resulting in a product that is better suited to the skin



CLEANERS AND DETERGENTS USES OF TRISODIUM CITRATE DIHYDRATE:
The major components of cleaning products are surfactants and builders.
Other ingredients are added to provide a variety of functions, e.g., increasing cleaning performance for specific soils/surfaces, ensuring product stability, and supplying a unique identity to a product.

Complex phosphates and Trisodium Citrate Dihydrate are common sequestering builders.
Builders enhance or maintain the cleaning efficiency of the surfactant.
The primary function of builders is to reduce water hardness.

This is done either by sequestration or chelation (holding hardness minerals in solution); by precipitation (forming an insoluble substance); or by ion exchange (trading electrically charged particles).
Builders can also supply and maintain alkalinity, which assists cleaning, especially of acid soils; help keep removed soil from redepositing during washing, and emulsify oily and greasy soils.



FUNCTIONS OF TRISODIUM CITRATE DIHYDRATE:
*Trisodium Citrate Dihydrate acts as an emulsifier
*Buffering agent
*Trisodium Citrate Dihydrate acts as a sequestrant



ALTERNATIVES OF TRISODIUM CITRATE DIHYDRATE:
*SODIUM POLYASPARTATE,
*SODIUM PHYTATE,
*SORBIC ACID,
*BENZOIC ACID



PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate's molecular formula is Na3C6H5O7, and its molecular weight or molar mass is 258.068 g/mol.
Trisodium Citrate Dihydrate's appearance is white and comes in the form of crystalline powder, or granular crystals.
Trisodium Citrate Dihydrate’s soluble in water and becomes deliquescent upon contact with moist air.

Trisodium Citrate Dihydrate’s insoluble in alcohol.
Trisodium Citrate Dihydrate has a sour taste like citric acid.
Trisodium Citrate Dihydrate has a total number of seven hydrogen bond acceptors and one hydrogen bond donor.

Monoisotopic mass of Trisodium Citrate Dihydrate is 257.973 g/mol.
The melting point of Trisodium Citrate Dihydrate is anywhere > (greater than) 3000 Celsius or 572 oF; 573K.



TRISODIUM CITRATE DIHYDRATE AT A GLANCE:
*Trisodium Citrate Dihydrate is a salt of citric acid, which can be derived from citrus
*Trisodium Citrate Dihydrate is primarily used to control the pH level of a product
*Trisodium Citrate Dihydrate has antioxidant and preservative properties
*Trisodium Citrate Dihydrate is also used in food and medical applications



WHAT DOES TRISODIUM CITRATE DIHYDRATE DO IN A FORMULATION?
*Buffering
*Chelating
*Preservative



FORMULA OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate's constituents are sodium and citric acid.
Trisodium Citrate Dihydrate's molecular formula is
C6H5Na3O7 or C6H5O7.3Na or Na3C6H5O7.

TriTrisodium Citrate Dihydrate or Trisodium 2-hydroxypropane-1,2,3-tricarboxylate are the IUPAC names for Trisodium Citrate Dihydrate.
Trisodium Citrate Dihydrate is also known by other names, such as Natrocitral Citrosodine.

Formation of Trisodium Citrate Dihydrate
When citric acid reacts with sodium bicarbonate in the presence of water in a bath bomb, this is formed.
C6H8O7 + 3NaHCO3 + H2O ⇢ Na3C6H5O7 + 3H2O + 3CO2



WHAT IS THE IMPACT OF TRISODIUM CITRATE DIHYDRATE ON THE BODY?
This is nothing more than a sodium salt with a citric acid base.
To reduce the urine’s acidity, Trisodium Citrate Dihydrate medication is used.
As a result, the kidneys can excrete uric acid, which can help prevent kidney stones and gout.

Trisodium Citrate Dihydrate can also treat and prevent kidney disease and metabolic issues such as acidosis.
In coagulation tests, Trisodium Citrate Dihydrate also functions as an anticoagulant.
Trisodium Citrate Dihydrate can aid in the prevention of coagulation by forming a calcium ion complex.
In all of these ways, Trisodium Citrate Dihydrate is used to treat and prevent diseases.



EXPLAIN THE SOLUBILITY OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is stable in dry air but becomes anhydrous when exposed to 150 °C.
Trisodium Citrate Dihydrate is 1.3 parts water soluble and 0.6 parts boiling water soluble.
Trisodium Citrate Dihydrate is almost entirely insoluble in alcohol.
According to material safety data sheets, Trisodium Citrate Dihydrate's solubility at 25° C is 29 grams/Liter and 42.5 grams/100 according to International Chemical Safety Cards (ICSC).



HOW TRISODIUM CITRATE DIHYDRATE IS PRODUCED COMMERCIALLY?
Trisodium Citrate Dihydrate is typically produced by mixing a bit of sodium carbonate monohydrate with a hot aqueous five-citric acid solution.
The resulting solution is evaporated until crystallization occurs. Another way to make Trisodium Citrate Dihydrate is to decompose calcium citrate with an alkali metal salt.
The sodium salt of ten citric acids is known to exist in two forms: the so-called pentahydrate,15, and the di-hydrate CsH5O7Na3.2H2O



CONCLUSION OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate, also called triTrisodium Citrate Dihydrate is formed when citric acid reacts with sodium bicarbonate in the presence of water in a bath bomb.
Trisodium Citrate Dihydrate is a compound widely used in industries, healthcare, food, and beverages.
Trisodium Citrate Dihydrate is a familiar pH adjuster and water softener.

Trisodium Citrate Dihydrate can be found in many personal care products, including liquid laundry detergent, shampoo, conditioner, sunscreen, facial moisturizer, makeup, and soap.
Trisodium Citrate Dihydrate is also commonly used to control acidity in foods and pharmaceuticals.



SAFETY PROFILE OF TRISODIUM CITRATE DIHYDRATE:
The Cosmetic Ingredient Review (CIR) Expert Panel has reviewed scientific literature and data on the safety of citric acid and its esters and salts, like Trisodium Citrate Dihydrate.

Their findings showed that citric acid, its esters, and salts did not irritate the eyes or cause skin irritation or allergic skin reactions at concentrations used in cosmetics and skincare products.
In light of the available scientific evidence, the Expert Panel came to the conclusion that citric acid, its esters, and salts were safe for use in cosmetics and personal care products under the circumstances at hand.



PHYSICAL and CHEMICAL PROPERTIES of TRISODIUM CITRATE DIHYDRATE:
CAS number: 6132-04-3
EC number: 200-675-3
Hill Formula: C₆H₅Na₃O₇ * 2 H₂O
Molar Mass: 294.10 g/mol
HS Code: 2918 15 00
Melting Point: 300 °C (anhydrous substance)
pH value: 7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density: 600 kg/m3
Solubility: 720 g/l
Molecular Weight: 294.10 g/mol
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 2
Exact Mass: 293.99396471 g/mol
Monoisotopic Mass: 293.99396471 g/mol
Topological Polar Surface Area: 143Ų
Heavy Atom Count: 18
Formal Charge: 0
Complexity: 211
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 6
Compound Is Canonicalized: Yes
Physical state: solid
Color: white
Odor: No data available
Melting point/freezing point:
Melting point: 300 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 7,5 - 9 at 29,4 g/l at 25 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility 29,4 g/l at 20 °C - completely soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Bulk density: ca.600 kg/m3
CAS NUMBER: 6132-04-3
MOLECULAR FORMULA: C6H5O7Na3·2H2O
BEILSTEIN REGISTRY NUMBER: 6104939
EC NUMBER: 200-675-3
MDL NUMBER: MFCD00150031
CBNumber:CB9752065
Molecular Formula:C6H9Na3O9

Molecular Weight:294.1
MDL Number:MFCD00150031
MOL File:6132-04-3.mol
Melting point: >300 °C(lit.)
Density: 1.76
FEMA: 3026 | SODIUM CITRATE
Flash point: 173.9 °C
storage temp.: Store at +5°C to +30°C.
solubility: H2O: 100 mg/mL
form: powder
color: white
PH: 7.0-9.0 (25℃, 50mg/mL in H2O)
Odor: Odorless
PH Range: 7.5 - 9 at 29.4 g/l at 25 °C
Water Solubility: 720 g/L (25 ºC)
λmax:
λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,8602
BRN: 6104939

Stability: Stable.
Incompatible with bases, reducing agents, oxidizing agents.
InChIKey: NLJMYIDDQXHKNR-UHFFFAOYSA-K
LogP: -1.72
CAS DataBase Reference: 6132-04-3(CAS DataBase Reference)
FDA UNII: B22547B95K
EPA Substance Registry System: 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate (6132-04-3)
IUPAC Name: trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate
Molecular Weight: 294.10
Molecular Formula: C6H9Na3O9
Canonical SMILES: C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.[Na+].[Na+].[Na+]
InChI: InChI=1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
InChIKey: NLJMYIDDQXHKNR-UHFFFAOYSA-K
Boiling Point: 309.6 °C at 760 mmHg
Melting Point: 300ºC
Flash Point: 155.2ºC
Density: 1.76 g/cm3
Solubility: Solubility in water, g/100ml: 77
Appearance: White powder or crystals
Storage: Store at RT.
Hazard Codes: Xi
Log P: -5.38120
PSA: 159.8

Refractive Index: 1.58
Risk Statements R37/38
RTECS: GE7810000
Safety Statements: S24/25
Stability: Stable.
Incompatible with bases, reducing agents, oxidizing agents.
Molecular Formula: C6H5O7Na3 ● 2 H2O
Molecular Weight: 294.10
CAS Number: 6132-04-3
E-NR: E 331
EINECS: 20-06-753
CAS No: 6132–04–3
EINECS No: 200–675–3
Empirical formula: C6H5Na3O7 . 2H2O
Molecular mass: 294.10 g/mol
Density: 1.7g/cm3
Appearance: colourless crystals or white, granular powder
pH: 8 – 8.7 at 50g/L at 25C
Melting point: >300 C
Solubility in water: 760 g/L (25C)
Easily soluble in hot water.
Soluble in cold water.

Insoluble in alcohol.
Soluble in 1.3 parts water.
Soluble in 0.6 parts boiling water.
Formula: Na₃C₆H₅O₇·2H₂O
MW: 294,1 g/mol
Melting Pt: 150 °C
Density: 1,76 g/cm³ (20 °C)
Storage Temperature: Ambient
MDL Number: MFCD00150031
CAS Number: 6132-04-3
EINECS: 200-675-3
Merck Index: 13,08675
Density: 1.76
Boiling Point: 309.6ºC at 760 mmHg
Melting Point: >300 °C(lit.)
Molecular Formula: C6H9Na3O9
Molecular Weight: 294.10
Flash Point: 173.9 °C
Exact Mass: 293.993958
PSA: 159.08000
Index of Refraction: 1.58
Storage condition: Store at RT.
Stability: Stable.
Incompatible with bases, reducing agents, oxidizing agents.
Water Solubility: 720 g/L (25 ºC)



FIRST AID MEASURES of TRISODIUM CITRATE DIHYDRATE:
-Description of first-aid measures
*If inhaled
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TRISODIUM CITRATE DIHYDRATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TRISODIUM CITRATE DIHYDRATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TRISODIUM CITRATE DIHYDRATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TRISODIUM CITRATE DIHYDRATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of TRISODIUM CITRATE DIHYDRATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
1,2,3-Propanetricarboxylic acid
2-hydroxy-, sodium salt, hydrate (1:3:2)
Citric acid, trisodium salt, dihydrate
1,2,3-Propanetricarboxylic acid
2-hydroxy-, trisodium salt, dihydrate
Sodium citrate dihydrate
Trisodium citrate dihydrate
N 1560
Trisodium citrate dihydrate
Sodium citrate dihydrate
6132-04-3
Sodium citrate tribasic dihydrate
Sodium citrate hydrate
1,2,3-Propanetricarboxylic acid
2-hydroxy-, trisodium salt, dihydrate
Citric acid trisodium salt dihydrate
MFCD00150031
B22547B95K
Nauzene
trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate
DTXSID1049437
SODIUM CITRATE, DIHYDRATE
Citric acid, trisodium salt, dihydrate
N-1560
Sodium citrate hydrous
Natrii citras, dehydrate
Trisodium citrate dihydrate
Citric acid trisodium salt dihydrate
MFCD00130806
tri-sodium citrate dihydrate
TRISODIUM CITRATE DIHYDRATE (II)
TRISODIUM CITRATE DIHYDRATE [II]
TRISODIUM CITRATE DIHYDRATE (USP MONOGRAPH)
TRISODIUM CITRATE DIHYDRATE [USP MONOGRAPH]
sodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
Sodiumcitrate
Tricitrasol
Natrum citricum
Emetrol Chewables
Tricitrasol (TN)
Sodium citrate
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
Sodium Citrate Dihydrate
Sodium citrate (TN)
CVS HealthNausea Relief
Emetrol Chewables Orange
Sodium citrate [USP:JAN]
Sodiumcitratetribasicdihydrate
Emetrol Chewables Mixed Berry
SODIUM CITRATE [FHFI]
DTXCID0029397
Sodium citrate hydrate (JP17)
UNII-B22547B95K
CHEBI:32142
Trisodium citrate dihydrate, ACS
NLJMYIDDQXHKNR-UHFFFAOYSA-K
SODIUM CITRATE HYDROUS [II]
SODIUM CITRATE HYDRATE [JAN]
SODIUM CITRATE [EP MONOGRAPH]
SODIUM CITRATE DIHYDRATE [MI]
AKOS025293920
Citronensaeure,Trinatrium-Salz-Dihydrat
Sodium citrate dihydrate, >=99%, FG
SODIUM CITRATE DIHYDRATE [VANDF]
BP-31019
SODIUM CITRATE DIHYDRATE [WHO-DD]
Sodium citrate tribasic dihydrate, >=98%
Sodium citrate dihydrate, ACS reagent grade
SODIUM CITRATE, DIHYDRATE [WHO-IP]
D01781
F82065
Sodium citrate tribasic dihydrate, AR, >=99%
Sodium citrate tribasic dihydrate, LR, >=99%
Citric acid trisodium salt dihydrate ACS reagent
NATRII CITRAS, DEHYDRATE [WHO-IP LATIN]
A833161
A835986
Q22075862
Sodium citrate dihydrate Biochemical grade, Fine Granular
Sodium citrate tribasic dihydrate, USP, 99.0-100.5%
Sodium Citrate Tribasic Dihydrate (Molecular Biology Grade)
Sodium citrate tribasic dihydrate, ACS reagent, >=99.0%
trisodium 2-oxidanylpropane-1,2,3-tricarboxylate dihydrate
Citric acid trisodium salt dihydrateTrisodium citrate dihydrate
Sodium citrate tribasic dihydrate, BioUltra, >=99.0% (NT)
Sodium citrate tribasic dihydrate, insect cell culture tested
Sodium citrate tribasic dihydrate, JIS special grade, >=99.0%
Sodium citrate tribasic dihydrate, p.a., ACS reagent, 99.0%
Sodium citrate tribasic dihydrate, purum p.a., >=99.0% (NT)
Sodium citrate tribasic dihydrate, SAJ first grade, >=99.0%
Sodium citrate tribasic dihydrate, tested according to Ph.Eur.
trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2)
Trisodium citrate dihydrate, meets USP testing specifications
2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate
Sodium citrate tribasic dihydrate, BioXtra, >=99.0% (titration)
Sodium citrate tribasic dihydrate, for molecular biology, >=99%
Sodium citrate tribasic dihydrate, Vetec(TM) reagent grade, 98%
Sodium citrate, United States Pharmacopeia (USP) Reference Standard
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, dihydrate
Sodium citrate tribasic dihydrate, p.a., ACS reagent, reag. ISO, 99-101%
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2)
Sodium citrate tribasic dihydrate, BioUltra, for molecular biology, >=99.5% (NT)
Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, >=99.0% (NT)
Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=99.0%
Sodium Citrate, Pharmaceutical Secondary Standard; Certified Reference Material
Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%
Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=98% (titration), powder
Sodium citrate tribasic dihydrate
Trisodium Citrate, Sodium Citrate, Dihydrate
Citric acid trisodium salt dihydrate
Trisodium citrate dihydrate
Citric Acid Trisodium Salt Dihydrate
Trisodium citrate dihydrate
Citronensaeure-tri-na-salz-dihydrat
Natriumcitrat-Dihydrat
1,2,3-Propanetricarboxylic acid
2-hydroxy-, trisodium salt, dihydrate
Sodium citrate tribasic dihydrate
Sodium Citrate, trisodium salt
CITRIC ACID MONO
SODIUM CITRATE TRIBASIC DIHYDRATE
TRI-SODIUM CITRATE DIHYDRATE
SodiuM Citrate (AS);NATRII CITRAS
SODIUM CITRATE, DIHYDRATE
ACIDUM CITRICUM MONOHYDRICUM
CITRIC ACID TRISODIUM SALT DIHYDRATE
BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE
abs9147
Sodium citrate dihydrate
Sodium citrate tribasic dihydrate
1,2,3-Propanetricarboxylic acid
2-hydroxy-, trisodium salt, dihydrate
Citric Acid Trisodium Salt Dihydrate
Trisodium citrate dihydrate
Citronensaeure-tri-na-salz-dihydrat
Natriumcitrat-Dihydrat
1,2,3-Propanetricarboxylic acid
2-hydroxy-, trisodium salt, dihydrate
Sodium citrate tribasic dihydrate
Sodium Citrate, trisodium salt
Sodium citrate dihydrate
Trisodium citrate, trisodium salt of 2-hydroxy-1,2,3-propanetricar­boxylic acid
trisodium salt of -hydroxy-tricarballylic acid
Natrocitral
Citrate sodique
Sodium Citrate Dihydrate
Sodium citrate tribasic dihydrate,Sodium Citrate
Dihydrate,Citric acid trisodium salt dihydrate
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate
Trisodium Citrate Dihydrate
TriTrisodium Citrate Dihydrate
Citrosodine
Citric acid, trisodium salt
E331
Trisodium Citrate Dihydrate
68-04-2
TRITRISODIUM CITRATE DIHYDRATE
Trisodium Citrate Dihydrate anhydrous
Citrosodine
Natrocitral
Trisodium Citrate Dihydrate, anhydrous
Citric acid, trisodium salt
TriTrisodium Citrate Dihydrate, anhydrous
anhydrous Trisodium Citrate Dihydrate
Citric acid trisodium salt
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt
Sodium 2-hydroxypropane-1,2,3-tricarboxylate
FEMA No. 3026
CCRIS 3293
Trisodium Citrate Dihydrate (Na3C6H5O7)
Trisodium Citrate Dihydrate,anhydrous
HSDB 5201
trisodium 2-hydroxypropane-1,2,3-tricarboxylate
trisodium-citrate
Anhydrous triTrisodium Citrate Dihydrate
UNII-RS7A450LGA
EINECS 200-675-3
Bicitra
Pneucid
Trisodium 2-hydroxy-1,2,3-propanetricarboxylate
994-36-5
CHEBI:53258
RS7A450LGA
INS NO.331(III)
INS-331(III)
EC 200-675-3
E-331(III)
trisodium;2-hydroxypropane-1,2,3-tricarboxylate
MFCD00012462
FEMA NO. 3026, ANHYDROUS-
Citrosodina
Citnatin
Citreme
Citrosodna
EINECS 213-618-2
Trisodium Citrate Dihydrate hydrous
TriTrisodium Citrate Dihydrate anhydrous
Natrii citras, dehydrate
E 331
Sodium 2-hydroxy-1,2,3-propanetricarboxylate
UNII-68538UP9SE
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt
EINECS 242-734-6
C6H5Na3O7
EC 242-734-6
Oracit
Natrii citras
tri-Trisodium Citrate Dihydrate
Trisodium Citrate Dihydrate salt
Albright's Solution
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:3)
sodium (iii) citrate
Trisodium Citrate Dihydrate (USP)
Modified Shohl's Solution
Anticoagulant Trisodium Citrate Dihydrate
1Q73Q2JULR
CHEMBL1355
TRISODIUM CITRATE DIHYDRATE (II)
TRISODIUM CITRATE DIHYDRATE [MI]
Citrate Concentrated Solution
DTXSID2026363
TRISODIUM CITRATE DIHYDRATE (USP-RS)
TRISODIUM CITRATE DIHYDRATE [WHO-IP]
2-Hydroxy-1,2,3-propanetricarboxylic acid, trisodium salt
Citric acid trisodium salt, 99%
HRXKRNGNAMMEHJ-UHFFFAOYSA-K
TRISODIUM CITRATE DIHYDRATE, UNSPECIFIED
NATRII CITRAS [WHO-IP LATIN]
TRISODIUM CITRATE DIHYDRATE (USP IMPURITY)
AKOS015915009
DB09154
TRISODIUM CITRATE DIHYDRATE ANHYDROUS [HSDB]
ANHYDROUS TRITRISODIUM CITRATE DIHYDRATE [II]
TRISODIUM CITRATE DIHYDRATE, UNSPECIFIED FORM
TRISODIUM CITRATE DIHYDRATE,ANHYDROUS [VANDF]
8055-55-8
AC-15008
E331
Trisodium Citrate Dihydrate dihydrate USP Fine Granular
TRISODIUM CITRATE DIHYDRATE, ANHYDROUS [WHO-IP]
FT-0623960
EN300-74572
D05855
D77308
ANHYDROUS TRITRISODIUM CITRATE DIHYDRATE [USP MONOGRAPH]
Q409728
J-520101
Citric acid trisodium salt, anhydrous, >=98% (GC)
Citric acid trisodium salt, Vetec(TM) reagent grade, 98%
2-Hydroxy-1,2,3-propanenetricarboxylic acid trisodium salt dihydrate
Trisodium Citrate Dihydrate tribasic dihydrate
Citric acid trisodium salt dihydrate
TriTrisodium Citrate Dihydrate dihydrate
1,2,3-Propanetricarboxylic acid
2-hydroxy, trisodium salt
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt (1:3)
Citric acid, trisodium salt
2-Hydroxy-1,2,3-propanetricarboxylic acid trisodium salt
Citnatin
Citra-lock
Citreme
Citrosodina
Citrosodine
Cystemme
Iona
Natrocitral
Trisodium Citrate Dihydrate
Trisodium Citrate Dihydrate anhydrous
Trisodium Citrate Dihydrate H
Unifine P 3
Urisal
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt
Citric acid, trisodium salt
Trisodium Citrate Dihydrate
Trisodium Citrate Dihydrate anhydrous
TriTrisodium Citrate Dihydrate
Citrato de trisodio, dihidrato
Citrate de trisodium, dihydrate
Trisodio citrato diidrato
Trinatriumcitraatdihydraat
2-Hydroxy-1,2,3-propanenetricarboxylic Acid Trisodium Salt Dihydrate
2-Hydroxy-,1,2,3-propanetricarboxylic Acid Trisodium Salt (9CI)
Citric Acid, Trisodium Salt (8CI)
Trisodium Citrate Dihydrate (Na3C6H5O7) (7CI)

Trisodium Citrate Dihydrate is the dihydrate of trisodium citrate.
Trisodium Citrate Dihydrate has a role as an anticoagulant.
Trisodium Citrate Dihydrate contains a sodium citrate.
Trisodium Citrate Dihydrate (C6H5Na3O7.2H2O) is a tribasic salt of citric acid.


CAS Number: 6132-04-3
EC Number 200-675-3
Molecular Formula: C6H9Na3O9 or C6H5Na3O7.2H2O


Trisodium Citrate Dihydrate has a sour taste similar to citric acid, and is salty as well.
Trisodium Citrate Dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.


Trisodium citrate dihydrate occurs as white, granular crystals or as white, crystalline powder with a pleasant, salty taste.
Trisodium Citrate Dihydrate is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96 %).
Trisodium citrate dihydrate is a non-toxic, neutral salt with low reactivity.


Trisodium Citrate Dihydrate is chemically stable if stored at ambient temperatures.
Trisodium citrate dihydrate is fully biodegradable and can be disposed of with regular waste or sewage.
Trisodium citrate dihydrate is available in various granulations.


Trisodium Citrate Dihydrate is soluble in water.
Trisodium Citrate Dihydrate is insoluble in alcohol.
Trisodium citrate dihydrate is a tribasic salt of citric acid.


Trisodium Citrate Dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.
Citric acid is the product of a microbial fermentation using carbohydrate substrates.
Trisodium citrate dihydrate is a chemical compound that is used as a buffer and to maintain the pH of solutions.


Trisodium Citrate Dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate is free soluble in water, practically insoluble in ethanol(96 percent).
Trisodium citrate dihydrate is a tribasic salt of citric acid.


Trisodium Citrate Dihydrate is produced by complete neutralization of citric acid with high purity sodium source (sodium hydroxide or sodium carbonate) and subsequent crystallization.
Trisodium Citrate Dihydrate is manufactured by neutralizing citric acid derived from a submerged fermentation process.
Trisodium Citrate Dihydrate is considered “GRAS” (Generally Recognized As Safe) by the United States Food and Drug


Administration without restriction as to the quantity of use within good manufacturing practice.
Trisodium Citrate Dihydrate is also considered by the Experts Committee of the FAO/WHO to be a safe food additive without limitation according to good manufacturing practice.


Trisodium Citrate Dihydrate is manufactured to meet the monograph specifications of major world codex and pharmacopoeia standards including the USP, FCC, BP, EP, FAO/WHO.
Cargill Trisodium Citrate Dihydrate is available as translucent white crystals and has a slight saline taste.
Water of crystallization constitutes approximately twelve percent by weight of the dihydrate form.


Citrate is a intermediate in the Trisodium Citrate Dihydrate cycle and fatty acid synthesis.
Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.
Trisodium Citrate Dihydrate possesses a saline, mildly tart flavor.


Trisodium Citrate Dihydrate is a useful reactant in organic synthesis.
Trisodium Citrate Dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate consists of colourless to white crystals and is practically odourless.


Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate is produced by complete neutralisation of citric acid with high purity sodium hydroxide or carbonate and subsequent crystallisation.
Citric acid is the product of a microbial fermentation using carbohydrate substrates.


Trisodium Citrate Dihydrate, (molecular formula: Na3C6H5O7 • 2H2O) has molecular weight of 294.1, is a colorless crystal or white crystalline powder product; it is odorless, salty taste, and cool.
Trisodium Citrate Dihydrate will lose its crystal water at 150 & deg;C and will be decomposed at even higher temperature.


Trisodium Citrate Dihydrate also has slight deliquescence in wet air and has weathering property upon hot air.
Trisodium Citrate Dihydrate is soluble in water and glycerol, but insoluble in alcohol and some other organic solvents.
Trisodium Citrate Dihydrate is a versatile chemical substance used in a variety of applications in different industries.


In the medical field, Trisodium Citrate Dihydrate is used as an anticoagulant but it is also an ingredient in many personal care products.
Trisodium Citrate Dihydrate can be used as Ph adjusting agents and emulsifying enhancers applied to jam, candy, jelly and ice cream; its combination with citric acid has an effect of alleviating tour.
Trisodium Citrate Dihydrate also has effects on forming complex with metal ions.


Trisodium Citrate Dihydrate is white powder or colourless crystals.
Trisodium Citrate Dihydrate is the tribasic dihydrate sodium salt of citric acid.
Trisodium Citrate Dihydrate is commonly used laboratory reagent.



USES and APPLICATIONS of TRISODIUM CITRATE DIHYDRATE:
In the cleaning industry Trisodium Citrate Dihydrate is commonly used because of its excellent cleaning characteristics and its unusual property of being almost neutral yet portraying the characteristics of an acid as in descalers and an alkali as in degreasers.
Cleaning products include laundry powders and detergents, toilet cleaners, hard surface cleaners, carpet cleaners, dish washing liquids, powder and liquid degreasers and pre-soaks.


Trisodium Citrate Dihydrate is becoming more and more popular now as it is considered environmentally friendly, it substitutes phosphates and is readily biodegradable.
In industry Trisodium Citrate Dihydrate finds many uses including alkaline degreaser baths, electroplating chemicals for copper and nickel etc, photo chemicals.
Trisodium Citrate Dihydrate is also used in the paper and pulp industries and the textiles industry.


Trisodium Citrate Dihydrate is often used as a food preservative, and as a flavoring in the food industry.
In the pharmaceutical industry it is used to control pH.
Trisodium Citrate Dihydrate may be used as an alkalizing agent, buffering agent, emulsifier, or sequestering agent.
Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.


Trisodium citrate dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium Citrate Dihydrate used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.


Trisodium citrate dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium Citrate Dihydrate used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.


Sodium salts of citric acid are used as buffers and food preservatives.
They are used medically as anticoagulants in stored blood, and for urine alkalization in the prevention of KIDNEY STONES.
Trisodium Citrate Dihydrate is the dihydrate of trisodium citrate.


Trisodium Citrate Dihydrate has a role as an anticoagulant.
Sodium salts of citric acid are used as buffers and food preservatives. Citric acid is one of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide.


Trisodium citrate dihydrate is widely used as an excellent pH regulator and odourless buffering agent for bath and shower gels, creams, styling or decorative products.
Trisodium Citrate Dihydrate is often used as an acidity regulator in pharmaceutical formulations and food products.
Trisodium citrate dihydrate has been shown to be effective at reducing the matrix effect and increasing the concentration response, which can lead to better analytical results.


Trisodium Citrate Dihydrate has also been shown to have anti-inflammatory properties, which may be due to its ability to prevent fatty acid production by inhibiting the enzyme lipase.
Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.


Trisodium Citrate Dihydrate is often used as a food preservative, and as a flavoring in the food industry.
In the pharmaceutical industry Trisodium Citrate Dihydrate is used to control pH.
Trisodium Citrate Dihydrate is used to enhance flavour and maintain stability of active ingredients in food and beverages.


In detergent industry, Trisodium Citrate Dihydrate can replace STPP as a kind of assistant.
Trisodium Citrate Dihydrate can also be used in fermentation, injection, photography and metal plating.
Trisodium Citrate Dihydrate is mildly basic and can be used along with citric acid to make biologically compatible buffers.


Trisodium Citrate is a white odorless chemical used as a food additive.
Trisodium Citrate Dihydrate is typically used as a flavoring agent or as a preservative.
Trisodium Citrate Dihydrate is used as flavoring agent in carbonated beverages contributing a tart flavor.


Trisodium Citrate Dihydrate is also found in gelatin mix, ice cream, yogurt, jams, sweets, milk powder, processed cheeses and bratwurst.
Trisodium Citrate Dihydrate is used as raw material for pharmaceuticals / Food additives.
A biological buffer, Trisodium Citrate Dihydrate is used for cell culture, in vitro, enzyme assays and some electrophoretic applications at physiological pH.


Trisodium Citrate Dihydrate is used in toothpastes & dental creams, effervescent denture cleansers, mouth rinses and oral hygiene products.
Trisodium citrate dihydrate is commonly used in various technical and industrial applications mainly as a pH buffering, sequestering or emulsifying agent.
Trisodium Citrate Dihydrate is also used as a retarder for mortar mixes.


Trisodium Citrate Dihydrate is effective to retard plaster mixes.
Trisodium Citrate Dihydrate must be used carefully as adding too much will prevent the plaster curing properly.
Premix the citrate in water first and add to the plaster mix.


Trisodium citrate dihydrate, also known as sodium citrate, is an organic compound that has white to colorless crystals.
Trisodium Citrate Dihydrate is odourless, with a cool salty taste. Stable in room temperature and air, slightly soluble in wet air, weathering in hot air.
Lose crystal water heated to 150 ℃.


Trisodium Citrate Dihydrate is easily soluble in water, glycerol, alcohol and other organic solvents.
Trisodium Citrate Dihydrate is decomposed by overheating, slightly deliviate in humid environment and slightly weathering in hot air.
Trisodium Citrate Dihydrate is manufactured by neutralizing citric acid derived from a submerged fermentation process.


Trisodium Citrate Dihydrate is available as translucent white crystals and has a slight saline taste.
Trisodium citrate dihydrate is a tribasic salt of citric acid.
Trisodium Citrate Dihydrate is produced by complete neutralization of citric acid with high purity sodium source and subsequent crystallization.


Buffers pH and enhances action of methyl parabens.
Trisodium Citrate Dihydrate, from Junbunzlauer is a buffering, sequestering and emulsifying agent.
Trisodium Citrate Dihydrate is a tribasic salt of citric acid and appears as a white granular powder that is non-toxic, freely soluble in water and practically insoluble in ethanol.


Due to its versatile nature, Trisodium Citrate Dihydrate is perfect for many areas, including Food and Beverages, Cosmetics and Industrial applications.
Trisodium citrate dihydrate is widely used in foods, beverages and various technical applications mainly as buffering, sequestering or emulsifying agent.
Trisodium Citrate Dihydrate has no toxic effect, and has pH adjusting capability as well as having a good stability, and therefore can be used in the food industry.


Trisodium Citrate Dihydrate has the greatest demand when being used as a food additive.
Trisodium Citrate Dihydrate is used as food additives.
Trisodium Citrate Dihydrate is mainly used as flavoring agents, buffers, emulsifiers, bulking agents, stabilizers and preservatives.


In addition, combination between Trisodium Citrate Dihydrate and citric acid can be used in a variety of jams, jelly, juice, drinks, cold drinks, dairy products and pastries gelling agents, flavoring agents and nutritional supplements.


In the food industry, Trisodium Citrate Dihydrate is used as a flavor enhancer, acidity regulator, and emulsifier.
Trisodium Citrate Dihydrate is also an essential ingredient in dishwasher tablets, industrial cleaners, detergents, etc.
Trisodium Citrate Dihydrate gets used in a many different places in food and beverage manufacture, though it's mainly used as a food additive for flavor and / or as a preservative.


Soft drinks, energy drinks, and club soda all use Trisodium Citrate Dihydrate for its tart flavour.
Trisodium Citrate Dihydrate is also used as a pH buffering agent in places like gelatins or mini milk containers.
It is also used as an anti-coagulant, Trisodium Citrate Dihydrate is ideal for keeping the fat globules from sticking together in the manufacture of many things such as ice cream.


Trisodium Citrate Dihydrate can be used as a food additive, as complex agent and buffering agent in electroplating industry; at the field of pharmaceutical industry.
Trisodium Citrate Dihydrate is used for the manufacturing of anti-clotting drugs; and used as the detergent additives in light industry.
Trisodium Citrate Dihydrate is used as the analysis agents used for chromatography analysis and can also used for preparing bacterial culture medium.


Moreover, Trisodium Citrate Dihydrate can also be applied into pharmaceutical industry.
Trisodium Citrate Dihydrate can be used for the flavoring processing of food, as stabilizers, buffers and deputy complex-forming agents in non-toxic electroplating industry; at pharmaceutical industry.


Trisodium Citrate Dihydrate is used as anti-clotting agent, phlegm drugs and diuretics drugs.
Trisodium Citrate Dihydrate can also be used in brewing, injection, newspaper and movies medicines.
Trisodium Citrate Dihydrate is chiefly used as a food additive, usually for flavor or as a preservative.


Trisodium Citrate Dihydrate is used as an anticoagulant for collection of blood.
Trisodium Citrate Dihydrate is used in photography; as sequestering agent to remove trace metals; as emulsifier, acidulant and sequestrant in foods.
Trisodium Citrate Dihydrate is used as an anticoagulant also used as a biological buffer


Trisodium Citrate Dihydrate, is widely applied in food, beverages and fillers as a buffering, sequestering or an emulsifying agent.
Trisodium Citrate Dihydrate used as an anticoagulant in blood transfusions, osmotic laxative, functional fluids, solvents cleaning, furnishing care products, laundry dishwashing products and cleaning automobile radiators.


-Pharmaceutical Applications:
Trisodium Citrate Dihydrate, as either the dihydrate or anhydrous material, is widely used in pharmaceutical formulations.
Trisodium Citrate Dihydrate is used in food products, primarily to adjust the pH of solutions.
Trisodium Citrate Dihydrate is also used as a sequestering agent.
The anhydrous material is used in effervescent tablet formulations.
Trisodium Citrate Dihydrate is additionally used as a blood anticoagulant either alone or in combination with other citrates such as disodium hydrogen citrate.
Therapeutically, Trisodium Citrate Dihydrate is used to relieve the painful irritation caused by cystitis, and also to treat dehydration and acidosis due to diarrhea.


-Applications of Trisodium Citrate Dihydrate:
• anticoagulant activity
• use as buffer or food preservatives
• citrate solution is designed to break protein cross-links
• as a calcium chelator


-Applications of Trisodium Citrate Dihydrate:
*Food
*Beverages
*Healthcare
*Personal Care
*Cleaners & Detergents


-Industrial Applications of Trisodium Citrate Dihydrate:
*Feed & Pet Food
*Pharma


-Uses of Trisodium Citrate Dihydrate:
*Buffering agent.
*Manufacture of household cleaners, degreasers and detergents.



CHARACTERISTICS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium citrate dihydrate occurs as white, granular crystals or as white, crystalline powder.
Trisodium Citrate Dihydrate is an odourless substance with a pleasant, salty taste.
Trisodium Citrate Dihydrate is slightly deliquescent in moist air, freely soluble in water and practically insoluble in ethanol (96%).

Trisodium citrate dihydrate is a non-toxic, neutral salt with low reactivity.
Trisodium Citrate Dihydrate is chemically stable if stored at ambient
temperatures.
Although Trisodium Citrate Dihydrate is not very hygroscopic, caking may occur upon prolonged storage at humidities higher than 70 %.
Trisodium citrate dihydrate is fully biodegradable and can be disposed of with regular waste or sewage.



CHEMICAL PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is colorless crystals or white crystalline powder, and is odorless, cool and salty.
Trisodium Citrate Dihydrate has no melting point with a relative density of 1.857.
Trisodium Citrate Dihydrate is stable in air at room temperature with loss of crystal water when being heated to 150 °C loss of crystal water; further heating will cause its decomposition.

Trisodium Citrate Dihydrate is insoluble in ethanol but highly soluble in water. 5% aqueous solution has a pH value of 7.6 to 8.6.
Trisodium Citrate Dihydrate consists of odorless, colorless, monoclinic crystals, or a white crystalline powder with a cooling, saline taste.
Trisodium Citrate Dihydrate is slightly deliquescent in moist air, and in warm dry air it is efflorescent.



EFFECT AND APPLICATION OF TRISODIUM CITRATE DIHYDRATE:
During the process of clinically taking fresh blood, adding some amount of sterile sodium citrate can play a role in prevent blood clotting; this is exactly taking advantage of the features that calcium citrate can form soluble complexes with calcium ion.
In the field of medicine, Trisodium Citrate Dihydrate is used for the in vitro anti-clotting drugs and anticoagulants drugs, phlegm drugs, and diuretics drugs during blood transfusions.

Trisodium Citrate Dihydrate can also used for cyanide-free electroplating industry.
Trisodium Citrate Dihydrate is also used as developer for photographic industry.
Trisodium Citrate Dihydrate can be used as flavoring agents, buffering materials, emulsifiers, and stabilizer in the food industry.

Moreover, Trisodium Citrate Dihydrate is also widely used in chemical, metallurgical industry, the absorption of sulfur dioxide exhaust with the absorption rate of 99% and regenerate liquid sulfur dioxide citrate for recycle application.
Trisodium Citrate Dihydrate has a good water solubility and a excellent cheating capability with Ca2 +, Mg2 + and other metal ions.

Trisodium Citrate Dihydrate is biodegradable and has a strong dispersing ability and anti-redeposition ability.
Daily-applied chemical detergents use Trisodium Citrate Dihydrate as alternative to trimer sodium phosphate for production of non-phosphorus detergent and phosphate-free liquid detergent.
Adding a certain amount Trisodium Citrate Dihydrate to the detergent can significantly increase the cleaning ability of detergent cleaning.

The large scale of application of sodium tripolyphosphate as a builder in detergents is an important discovery in synthetic detergent industry.
Trisodium Citrate Dihydrate is non-toxic without environmental pollution.
Trisodium Citrate Dihydrate can also be acted as a buffer for the production of cosmetics.



KEY BENEFITS OF TRISODIUM CITRATE DIHYDRATE:
• Non-toxic
• Low Reactivity
• Chemically stable
• Fully biodegradable
• Can be disposed of with regular waste or sewage



FUNCTIONS AND APPLICATIONS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is used as acidity regulator, flavor agent and stabilizer in food and beverage industry.
Trisodium Citrate Dihydrate is used as an anticoagulant, phlegm dispersant and diuretic in the pharmaceutical industry.
In detergent industry, Trisodium Citrate Dihydrate can be substituted as non-toxic detergent additive.
Trisodium Citrate Dihydrate is also used in brewing, injection, photographic medicine and electroplating.



EXCELLENT PERFORMANCE OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is currently the most important citrate.
Trisodium Citrate Dihydrate is produced by two steps: first starch food is fermented to generate citric acid; secondly, citric acid is neutralized by alkali to generate the final products.



PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
*Dihydrate
*White
*Granular crystals or crystalline powder
*Typical, practically odourless
*Pleasantly salty
*Freely soluble in water
*Practically insoluble in ethanol (96 %)
*Non-toxic
*Low reactive
*Chemically and microbiologically stable
*Fully biodegradable



MAIN FUNCTIONS OF TRISODIUM CITRATE DIHYDRATE:
*pH regulator
*Chelating agent
*Buffering agent
*Flavour enhancer
*Stabiliser
*Emulsifying agent



PRODUCTION METHODS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate is produced by the neutralization of citric acid by sodium hydroxide or sodium bicarbonate.
Dissolve sodium bicarbonate in water upon stirring and heating; add citric acid, continue to heat up to 85-90 °C; adjust the pH to 6.8; adjust active carbon for bleaching.
Filter when the mixture is still hot; condense the filtrate under reduced pressure; cool and the crystal comes out; filter, wash, dry to obtain the final products of
Trisodium Citrate Dihydrate.
C6H8O7 + 3NaHCO3 → C6H5Na3O7 • 2H2O + 3CO2 ↑ + H2O
Trisodium Citrate Dihydrate is prepared by adding sodium carbonate to a solution of citric acid until effervescence ceases.
The resulting solution is filtered and evaporated to dryness.



SAFE AND NONTOXIC PROPERTIES OF TRISODIUM CITRATE DIHYDRATE:
Since the basic raw material for the preparation of Trisodium Citrate Dihydrate mainly comes from the food, it is absolutely safe and reliable without causing harm to human health.
The United Nations Food and Agriculture and the World Health Organization has no restriction in its daily intake, which means that this product can be considered as non-toxic food.

It is biodegradable.
After subjecting to the dilution of a large amount of water, Trisodium Citrate Dihydrate is partially converted into citrate, which coexists with sodium citrate in the same system.

Citrate is easy to subject to biological degradation at water by the action of oxygen, heat, light, bacteria and microbes.
Trisodium Citrate Dihydrate's decomposition pathways are generally going through aconitic acid, itaconic acid, citraconic acid anhydride to be further converted to carbon dioxide and water.

The ability to form complexes with metal ions.
Trisodium Citrate Dihydrate has a good capability of forming complex with some metal ions such as Ca2+, Mg2+; for other ions such as Fe2+, it also has a good complex-forming ability.
Excellent solubility, and the solubility increases with increasing temperature of water.

Trisodium Citrate Dihydrate has a good capability for pH adjustment and a good buffering property.
Trisodium Citrate Dihydrate is a weak acid-strong alkali salt; When combined with citrate, they can form a pH buffer with strong compatibility; therefore, this is very useful for some cases in which it is not suitable to have large change of pH value.
In addition, Trisodium Citrate Dihydrate also has excellent retardation performance and stability.



BIOCHEM/PHYSIOL ACTIONS OF TRISODIUM CITRATE DIHYDRATE:
Trisodium Citrate Dihydrate can act as a buffering agent, resisting changes in pH.
Trisodium Citrate Dihydrate is used in blood collection tubes, the citrate chelates calcium ions in blood and thereby disrupts blood clotting.
Citrate is a intermediate in the TCA cycle and fatty acid synthesis.
Citrate is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA.



PHYSICAL and CHEMICAL PROPERTIES of TRISODIUM CITRATE DIHYDRATE:
Molecular Weight: 294.10
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 9
Rotatable Bond Count: 2
Exact Mass: 293.99396471
Monoisotopic Mass: 293.99396471
Topological Polar Surface Area: 143 Ų
Heavy Atom Count: 18
Formal Charge: 0
Complexity: 211
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 6
Compound Is Canonicalized: Yes
CAS number: 6132-04-3
EC number: 200-675-3
Hill Formula: C₆H₅Na₃O₇ * 2 H₂O
Molar Mass: 294.10 g/mol
HS Code: 2918 15 00
Melting Point: 300 °C (anhydrous substance)
pH value: 7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density: 600 kg/m3
Solubility: 720 g/l

Appearance Form: powder
Color: white
Odor: No data available
Odor Threshold: No data available
pH: 7,5 - 9 at 29,4 g/l at 25 °C
Melting point/freezing point:
Melting point/range: > 300 °C
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: 29,4 g/l at 20 °C - completely soluble
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Water Solubility: 73.7 mg/mL
logP: -0.55
logP: -1.3
logS: -0.54
pKa (Strongest Acidic): 3.05
pKa (Strongest Basic): -4.2
Physiological Charge: -3
Hydrogen Acceptor Count: 7
Hydrogen Donor Count: 1
Polar Surface Area: 140.62 Å2
Rotatable Bond Count: 5
Refractivity: 68.14 m3·mol-1
Polarizability: 14.27 Å3
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No

Melting Point: 150°C (in -2H2O)
Density: 1.76
Odor: Odorless
Quantity: 10,000 g
Beilstein: 6104939
Merck Index: 14,8602
Solubility Information: Soluble in water.
Insoluble in alcohol.
Formula Weight: 294.10 (258.07 Anhydrous)
Percent Purity: 99%
Chemical Name or Material: Trisodium citrate dihydrate
CAS No: 6132–04–3
EINECS No: 200–675–3
Empirical formula: C6H5Na3O7 . 2H2O
Molecular mass: 294.10 g/mol
Density: 1.7g/cm3
Appearance: colourless crystals or white, granular powder
pH: 8 – 8.7 at 50g/L at 25C
Melting point: >300 C
Solubility in water: 760 g/L (25C)

Easily soluble in hot water.
Soluble in cold water.
Insoluble in alcohol.
Soluble in 1.3 parts water.
Soluble in 0.6 parts boiling water.
Melting point: >300 °C(lit.)
Density: 1.76
FEMA: 3026 | SODIUM CITRATE
Flash point: 173.9 °C
storage temp.: Store at +5°C to +30°C.
solubility: H2O: 100 mg/mL
form: powder
color: white
PH: 7.0-9.0 (25℃, 50mg/mL in H2O)
Odor: Odorless
PH Range: 7.5 - 9 at 29.4 g/l at 25 °C
Water Solubility: 720 g/L (25 ºC)
λmax: λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01
Merck: 14,8602
BRN: 6104939
Stability: Stable.
Incompatible with bases, reducing agents, oxidizing agents.

Appearance: White crystals or crystalline powder
Odor: Characteristic
Clarity and color of Solution: Conforms
Loss on drying: 11.0 - 13.0%
Usage: acidity regulator etc.
Pb: < 10ppm
Assay: 99.0 - 101.0%
Chemical formula: C6H5­O7Na3.2H2O
Sulfate (SO4): 150 ppm max
Chloride (Cl): 50 ppm max
Alkalinity: Conforms
Oxalate: 300 ppm max
Storage: in the shade cool
Boiling Point: 309.6 °C at 760 mmHg
Melting Point: 300ºC
Flash Point:155.2ºC
Density: 1.76 g/cm3
Solubility: Solubility in water, g/100ml: 77
Appearance: White powder or crystals
Storage: Store at RT.
Hazard Codes: Xi
Log P: -5.38120
PSA: 159.8
Refractive Index: 1.58
Risk Statements: R37/38
RTECS: GE7810000
Safety Statements: S24/25
Stability: Stable.



FIRST AID MEASURES of TRISODIUM CITRATE DIHYDRATE:
-Description of first-aid measures
*If inhaled
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TRISODIUM CITRATE DIHYDRATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TRISODIUM CITRATE DIHYDRATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TRISODIUM CITRATE DIHYDRATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TRISODIUM CITRATE DIHYDRATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of TRISODIUM CITRATE DIHYDRATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Trisodium citrate dihydrate
Sodium citrate dihydrate
6132-04-3
Sodium citrate tribasic dihydrate
Sodium citrate hydrate
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate
Citric acid trisodium salt dihydrate
trisodium;2-hydroxypropane-1,2,3-tricarboxylate;dihydrate
MFCD00150031
trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
SODIUM CITRATE, DIHYDRATE
B22547B95K
Citric acid, trisodium salt, dihydrate
Sodium citrate hydrous
Trisodium citrate dihydrate;Citric acid trisodium salt dihydrate
MFCD00130806
tri-sodium citrate dihydrate
sodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
Sodiumcitrate
N-1560
Natrum citricum
Tricitrasol (TN)
Sodium citrate (TN)
Sodium citrate [USP:JAN]
Sodiumcitratetribasicdihydrate
SODIUM CITRATE [FHFI]
DTXSID1049437
Sodium citrate hydrate (JP17)
UNII-B22547B95K
CHEBI:32142
Trisodium citrate dihydrate, ACS
SODIUM CITRATE HYDROUS [II]
SODIUM CITRATE HYDRATE [JAN]
SODIUM CITRATE [EP MONOGRAPH]
SODIUM CITRATE DIHYDRATE [MI]
AKOS025293920
Citronensaeure,Trinatrium-Salz-Dihydrat
Sodium citrate dihydrate, >=99%, FG
SODIUM CITRATE DIHYDRATE [VANDF]
TRISODIUM CITRATE DIHYDRATE [II]
BP-31019
SODIUM CITRATE DIHYDRATE [WHO-DD]
Sodium citrate tribasic dihydrate, >=98%
Sodium citrate dihydrate, ACS reagent grade
SODIUM CITRATE, DIHYDRATE [WHO-IP]
D01781
F82065
Sodium citrate tribasic dihydrate, AR, >=99%
Sodium citrate tribasic dihydrate, LR, >=99%
Citric acid trisodium salt dihydrate ACS reagent
NATRII CITRAS, DEHYDRATE [WHO-IP LATIN]
A833161
A835986
TRISODIUM CITRATE DIHYDRATE [USP MONOGRAPH]
Q22075862
Sodium citrate dihydrate Biochemical grade, Fine Granular
Sodium citrate tribasic dihydrate, USP, 99.0-100.5%
Sodium Citrate Tribasic Dihydrate (Molecular Biology Grade)
Sodium citrate tribasic dihydrate, ACS reagent, >=99.0%
trisodium 2-oxidanylpropane-1,2,3-tricarboxylate dihydrate
Citric acid trisodium salt dihydrateTrisodium citrate dihydrate
Sodium citrate tribasic dihydrate, BioUltra, >=99.0% (NT)
Sodium citrate tribasic dihydrate, insect cell culture tested
Sodium citrate tribasic dihydrate, JIS special grade, >=99.0%
Sodium citrate tribasic dihydrate, p.a., ACS reagent, 99.0%
Sodium citrate tribasic dihydrate, purum p.a., >=99.0% (NT)
Sodium citrate tribasic dihydrate, SAJ first grade, >=99.0%
Sodium citrate tribasic dihydrate, tested according to Ph.Eur.
trisodium 2-hydroxypropane-1,2,3-tricarboxylate--water (1/2)
Trisodium citrate dihydrate, meets USP testing specifications
2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate
Sodium citrate tribasic dihydrate, BioXtra, >=99.0% (titration)
Sodium citrate tribasic dihydrate, for molecular biology, >=99%
Sodium citrate tribasic dihydrate, Vetec(TM) reagent grade, 98%
Sodium citrate, United States Pharmacopeia (USP) Reference Standard
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, dihydrate
Sodium citrate tribasic dihydrate, p.a., ACS reagent, reag. ISO, 99-101%
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, sodium salt, hydrate (1:3:2)
Sodium citrate tribasic dihydrate, BioUltra, for molecular biology, >=99.5% (NT)
Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, >=99.0% (NT)
Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=99.0%
Sodium Citrate, Pharmaceutical Secondary Standard; Certified Reference Material
Sodium citrate tribasic dihydrate, puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%
Sodium citrate tribasic dihydrate, suitable for amino acid analysis, >=98% (titration), powder
Sodium Citrate, Dihydrate
Citric acid trisodium salt dihydrate
Sodium Citrate Dihydrate
Sodium citrate tribasic dihydrate
Trisodium citrate
Sodium citrate dihydrate
Citric acid tridosium salt dihydrate
Trisodium citrate, dihydrate, Citric acid
Trisodium Salt, Dihydrate,
Sodium citrate dihydrate
Sodium citrate tribasic dihydrate
1,2,3-Propanetricarboxylic acid, 2-hydroxy-
trisodium salt, dihydrate
2-hydroxy-1,2,3-propanetricarboxylic acid trisodium salt dihydrate
Sodium citrate hydrate
Trisodium citrate dihydrate
Sodium citrate dihydrate
Sodium citrate tribasic dihydrate
Citric acid trisodium salt dihydrate
Trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate
CITRIC ACID MONO
SODIUM CITRATE TRIBASIC DIHYDRATE
TRI-SODIUM CITRATE DIHYDRATE
SodiuM Citrate (AS)
NATRII CITRAS
SODIUM CITRATE, DIHYDRATE
ACIDUM CITRICUM MONOHYDRICUM
CITRIC ACID TRISODIUM SALT DIHYDRATE
BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE
abs9147
1,2,3-Propanetricarboxylicacid
2-hydroxy-,trisodiumsalt,dihydrate
ANTI-BABOON IGM, BIOTIN
BETA-HYDROXY-TRICARBOXYLIC ACID MONOHYDRATE
HYDROXYTRICARBALLYLIC ACID MONOHYDRATE
CITRIC ACID NA3-SALT 2H2O
CITRIC ACID H2O
CITRIC ACID TRISODIUM SALT DIHYDRATE
CITRIC ACID, 3NA, DIHYDRATE
6132-04-3
1,2,3-PROPANETRICARBOXYLIC ACID, 2-HYDROXY-, TRISODIUM SALT, DIHYDRATE
CITRIC ACID, TRISODIUM SALT, DIHYDRATE
FEMA NO. 3026
N-1560
NATRII CITRAS, DEHYDRATE [WHO-IP LATIN]
SODIUM CITRATE [EP MONOGRAPH]
SODIUM CITRATE [FHFI]
SODIUM CITRATE DIHYDRATE
SODIUM CITRATE DIHYDRATE [MI]
SODIUM CITRATE DIHYDRATE [VANDF]
SODIUM CITRATE DIHYDRATE [WHO-DD]
SODIUM CITRATE HYDRATE
SODIUM CITRATE HYDRATE [JAN]
SODIUM CITRATE HYDROUS
SODIUM CITRATE HYDROUS [II]
SODIUM CITRATE, DIHYDRATE
SODIUM CITRATE, DIHYDRATE [WHO-IP]
TRISODIUM CITRATE DIHYDRATE [II]
TRISODIUM CITRATE DIHYDRATE [USP MONOGRAPH]