Tetradecanedioic Acid; 1,12-Dodecanedicarboxylic acid; Tetradecandisäure; ácido tetradecanodioico; Acide tétradecanedioïque; Tetradecane-1,14-dioic acid; CAS NO: 821-38-5

1,11-Diamino-3,6,9-triazaundecane; TEPA; N-(2-Aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-1,2-Ethanediamine; 1,4,7,10,13-Pentaazatridecane; 3,6,9-Triazaundecamethylenediamine cas no: 112-57-2

Tetradecanoic acid (Myristic acid), is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH.
Tetradecanoic acid (Myristic acid) is a salt or ester of myristic acid.
Tetradecanoic acid (Myristic acid) is named after the nutmeg Myristica fragrans.

CAS: 544-63-8
MF: C14H28O2
MW: 228.37
EINECS: 208-875-2

Nutmeg butter is 75 % trimyristin, the triglyceride of Tetradecanoic acid (Myristic acid).
Besides nutmeg, Tetradecanoic acid (Myristic acid) is also found in palm kernel oil, coconut oil, butter fat and is a minor component of many other animal fats.
Tetradecanoic acid (Myristic acid) is also found in spermaceti, the crystallized fraction of oil from the sperm whale.
Tetradecanoic acid (Myristic acid) is also commonly added co-translationally to the penultimate, nitrogen-terminus, glycine in receptor-associated kinases to confer the membrane localisation of the enzyme.
Tetradecanoic acid (Myristic acid) has a sufficiently high hydrophobicity to become incorporated into the fatty acyl core of the phospholipid bilayer of the plasma membrane of the eukaryotic cell.
In this way, Tetradecanoic acid (Myristic acid) acts as a lipid anchor in biomembranes.

Tetradecanoic acid (Myristic acid) is used in cosmetic and topical medicinal preparations where good absorption through the skin is desired.
Reduction of Tetradecanoic acid (Myristic acid) yields myristyl aldehyde and myristyl alcohol.
Tetradecanoic acid (Myristic acid) is a 14-carbon saturated fatty acid.
Tetradecanoic acid (Myristic acid) is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.
A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat.
Tetradecanoic acid (Myristic acid) is a common saturated fatty acid with the molecular formula CH3(CH2)12COOH.

Tetradecanoic acid (Myristic acid)'s salts and esters are commonly referred to as myristates or tetradecanoates.
Tetradecanoic acid (Myristic acid) is named after the binomial name for nutmeg (Myristica fragrans), from which it was first isolated in 1841.
Tetradecanoic acid (Myristic acid) is a saturated fatty acid containing 14 carbon atoms and is commonly found in animal and vegetable fats.
Tetradecanoic acid (Myristic acid) is an important component of many biological processes, including cell membrane formation, signal transduction, and energy metabolism.

The synthesis of Tetradecanoic acid (Myristic acid) from other fatty acids is essential for the production of a wide range of products, including pharmaceuticals, food additives, and cosmetics.
Tetradecanoic acid (Myristic acid) can be used in a variety of laboratory experiments.
Tetradecanoic acid (Myristic acid) is relatively easy to synthesize and is widely available, making it an ideal material for research.
However, Tetradecanoic acid (Myristic acid) is important to note that myristic acid is a saturated fatty acid and can be toxic in large doses, so care must be taken when using it in laboratory experiments.

Tetradecanoic acid (Myristic acid) Chemical Properties
Melting point: 52-54 °C(lit.)
Boiling point: 250 °C100 mm Hg(lit.)
Density: 0.862
Vapor pressure: FEMA: 2764 | MYRISTIC ACID
Refractive index: nD60 1.4305; nD70 1.4273
Fp: >230 °F
Storage temp.: room temp
Solubility: 1.07mg/l
pka: 4.78±0.10(Predicted)
Form: Flakes, Powder, Chunks or Crystalline Mass
Color: White
Odor: at 100.00 %. waxy fatty soapy coconut
Odor Type: waxy
Water Solubility: Merck: 14,6333
JECFA Number: 113
BRN: 508624
Stability: Stable. Incompatible with strong oxidizing agents, bases.
LogP: 5.79
CAS DataBase Reference: 544-63-8(CAS DataBase Reference)
NIST Chemistry Reference: Tetradecanoic acid (Myristic acid) (544-63-8)
EPA Substance Registry System: Tetradecanoic acid (Myristic acid) (544-63-8)

Tetradecanoic acid (Myristic acid) appears as white to yellowish white solid, sometimes appearing as shiny crystalline solid, or white to yellowish white powder.
Tetradecanoic acid (Myristic acid) has a relative density of 0.8739 (80 ℃), melting point of 54.5 ℃ and the boiling point of 326.2 ℃.
Tetradecanoic acid (Myristic acid)'s refractive index (nD60) is 1.4310.
Tetradecanoic acid (Myristic acid) is not soluble in water but soluble in ethanol, ether and chloroform.
Tetradecanoic acid (Myristic acid) contains about 70% to 80% while other kinds of coconut oil, palm kernel oil also contain it.

Application
Tetradecanoic acid (Myristic acid) can be used as a chemical agent, also for the synthesis of spices and organic matter.
Tetradecanoic acid (Myristic acid) can be used in the manufacture of emulsifiers, waterproofing agents, curing agents, PVC heat stabilizers and plasticizers, and also used as the raw materials of spices and pharmaceutical.
Tetradecanoic acid (Myristic acid) is mainly used as raw materials for the production of surfactants for the production of sorbitan fatty acid esters, glycerol fatty acid esters, ethylene glycol or propylene glycol fatty acid esters.
Tetradecanoic acid (Myristic acid) can also be used for the production of isopropyl myristate and so on.
Tetradecanoic acid (Myristic acid) can also be used for defoamers and flavoring agent.

According to the provision of China GB2760-89, Tetradecanoic acid (Myristic acid) can be used to prepare a variety of food spices.
Tetradecanoic acid (Myristic acid) is a surfactant and cleansing agent.
When combined with potassium, Tetradecanoic acid (Myristic acid) soap provides very good, abundant lather.
Tetradecanoic acid (Myristic acid) is a solid organic acid naturally occurring in butter acids such as nutmeg, oil of lovage, coconut oil, mace oil, and most animal and vegetable fats.
Although some sources cite Tetradecanoic acid (Myristic acid) as having no irritation potential, they do indicate comedogenicity potential.
Tetradecanoic acid (Myristic acid) is a fatty acid obtained from coconut oil and other fats.
Tetradecanoic acid (Myristic acid) has poor water solubility but is soluble in alcohol, chloro- form, and ether.
Tetradecanoic acid (Myristic acid) is used as a lubricant, binder, and defoaming agent.

Tetradecanoic acid (Myristic acid) is a common saturated fatty acid found in nutmeg, palm kernel oil, coconut oil and butter fat.
Tetradecanoic acid (Myristic acid) is a 14-carbon saturated (14:0) fatty acid.
In vivo, Tetradecanoic acid (Myristic acid) is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.
In addition, there are examples where N-myristoylation occurs post-translationally, when a hidden myristoylation pattern is exposed.

Pharmaceutical Applications
Tetradecanoic acid (Myristic acid) is used in oral and topical pharmaceutical formulations.
Tetradecanoic acid (Myristic acid) has been evaluated as a penetration enhancer in melatonin transdermal patches in rats and bupropion formulations on human cadaver skin.
Further studies have assessed the suitability of Tetradecanoic acid (Myristic acid) in oxymorphone formulations and clobetasol 17-propionate topical applications.
Furthermore, polyvinyl alcohol substituted withTetradecanoic acid (Myristic acid) at different substitution degrees has been used for the preparation of biodegradable microspheres containing progesterone or indomethacin.

Preparation
To prepare the Tetradecanoic acid (Myristic acid), the methyl ester of the mixed fatty acids or mixed fatty acid methyl ester obtained from the coconut oil or palm kernel oil is subject to vacuum fractionation, obtaining myristic acid.
For laboratory preparation, glycerol tris (tetradecanoate) is subject to saponification with 10% sodium hydroxide solution, further being acidified with hydrochloric acid to obtain the free Tetradecanoic acid (Myristic acid).
Tetradecanoic acid (Myristic acid) can also be made from tetradecanol.

Reactivity Profile
Tetradecanoic acid (Myristic acid) is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.
Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water.
Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions.

The pH of solutions of carboxylic acids is therefore less than 7.0.
Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt.
Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.
Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Tetradecanoic acid (Myristic acid) to corrode or dissolve iron, steel, and aluminum parts and containers.
Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.

The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.
Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides.
Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat.

Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat.
Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents.
These reactions generate heat.
A wide variety of products is possible.
Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions.

Biochem/physiol Actions
Tetradecanoic acid (Myristic acid) is commonly added via a covalent linkage to the N-terminal glycine of many eukaryotic and viral proteins, a process called myristoylation.
Myristoylation enables proteins to bind to cell membranes and facilitates protein-protein interactions.
Myristolyation of proteins affect many cellular functions and thus has implications in health and disease.

Synonyms
Tetradecanoic acid
MYRISTIC ACID
544-63-8
n-Tetradecanoic acid
Crodacid
n-Tetradecan-1-oic acid
n-Tetradecoic acid
1-Tridecanecarboxylic acid
Hydrofol acid 1495
Myristinsaeure
Univol U 316S
Emery 655
Myristate
tetradecoic acid
Hystrene 9014
Myristic acid, pure
FEMA No. 2764
Myristic acid (natural)
acide tetradecanoique
n-Myristic acid
NSC 5028
CCRIS 4724
HSDB 5686
Tetradecanoate
Philacid 1400
C14:0
Prifac 2942
CH3-[CH2]12-COOH
CHEBI:28875
AI3-15381
NSC-5028
1-tetradecanecarboxylic acid
EINECS 208-875-2
PHILACID-1400
UNII-0I3V7S25AW
PRIFRAC-2942
BRN 0508624
0I3V7S25AW
Myristic acid [NF]
DTXSID6021666
Edenor C 14
MyristicAcid-13C14
CHEMBL111077
DTXCID501666
MYRISTIC-14-13C ACID
NSC5028
4-02-00-01126 (Beilstein Handbook Reference)
MFCD00002744
FA 14:0
n-tetradecan-1-oate
MYRISTIC ACID (II)
MYRISTIC ACID [II]
MYRISTIC ACID (MART.)
MYRISTIC ACID [MART.]
MYRISTIC ACID (USP-RS)
MYRISTIC ACID [USP-RS]
CH3-(CH2)12-COOH
62217-70-3
32112-52-0
Acid, Myristic
CAS-544-63-8
Acid, Tetradecanoic
myristoate
myristoic acid
n-Tetradecanoate
Tetradecanoicacid
3usx
Myristic acid pure
Myristic Acid Flake
fatty acid 14:0
Hystrene 9514
Myristic Acid 655
TETRADECANSAEURE
1-Tridecanecarboxylate
ACIDO MYNISTICO
MAGNESIUMARSENATE
Myristic acid, 95%
Myristic acid, natural
tridecanecarboxylic acid
Myristic acid (8CI)
Myristic Acid, Reagent
3v2n
3w9k
Myristic acid, puriss.
Univol U 3165
Myristic acid, ?99%
Tetradecanoic acid (9CI)
bmse000737
D08OBF
Epitope ID:176772
MYRISTIC ACID [MI]
SCHEMBL6374
MYRISTIC ACID [FCC]
MYRISTIC ACID [FHFI]
MYRISTIC ACID [HSDB]
MYRISTIC ACID [INCI]
MLS002152942
WLN: QV13
Tetradecanoic (Myristic) acid
GTPL2806
NAA 104
NAA 142
IS_D27-TETRADECANOIC ACID
HMS3039E15
HMS3648O20
Myristic acid, analytical standard
HY-N2041
EINECS 250-924-5
Myristic acid, >=98.0% (GC)
Tetradecanoic acid; (Myristic acid)
Tox21_201852
Tox21_302781
BDBM50147581
LMFA01010014
LS-210
s5617
STL185697
Myristic acid, >=95%, FCC, FG
Myristic acid, Sigma Grade, >=99%
AKOS009156714
CCG-266785
DB08231
DS-3833
NSC 122834
NCGC00091068-01
NCGC00091068-02
NCGC00091068-03
NCGC00256547-01
NCGC00259401-01
AC-34674
BP-27915
SMR001224536
CS-0018531
FT-0602832
FT-0770860
M0476
EN300-78099
C06424
Myristic acid, Vetec(TM) reagent grade, 98%
Q422658
SR-01000854525
MYRISTIC ACID (CONSTITUENT OF SAW PALMETTO)
SR-01000854525-3
W-109088
F8889-5016
Z1954802504
EDAE4876-C383-4AD4-A419-10C0550931DB
MYRISTIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC]
Myristic acid, United States Pharmacopeia (USP) Reference Standard
Tetradecanoic acid; 1-Tridecanecarboxylic acid; n-Tetradecanoic acid
Myristic acid, Pharmaceutical Secondary Standard; Certified Reference Material

1,11-Diamino-3,6,9-triazaundecane; TEPA; N-(2-Aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-1,2-Ethanediamine; 1,4,7,10,13-Pentaazatridecane; 3,6,9-Triazaundecamethylenediamine; cas no: 112-57-2

1,11-Diamino-3,6,9-triazaundecane; TEPA; N-(2-Aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-1,2-Ethanediamine; 1,4,7,10,13-Pentaazatridecane; 3,6,9-Triazaundecamethylenediamine cas no: 112-57-2

Tetraethylenepentamine (TEPA ) is a polyazaalkane.
Tetraethylenepentamine (TEPA ) has a role as a copper chelator.
Tetraethylenepentamine (TEPA ) is a yellow, viscous liquid.

CAS: 112-57-2
MF: C8H23N5
MW: 189.3
EINECS: 203-986-2

A viscous liquid.
Slightly less dense than water.
Vapors heavier than air.
Corrosive to the eyes, skin, mouth, throat and stomach.
Vapors irritate the eyes and corrosive to the upper respiratory tract.
Vapors may irritate the eyes.
Flash point 325°F.
Tetraethylenepentamine (TEPA ) can be used as a reagent: To functionalize magnesium 2,5-dihydroxyterephthalate (Mg-MOF-74) to enhance the CO2 adsorption performance of the material.

To modify magnetic chitosan resin to form amine-bearing chitosan for the efficient removal of uranium from an aqueous solution.
Tetraethylenepentamine (TEPA ) is an organic compound and is in the class of chemicals known as ethyleneamines.
Tetraethylenepentamine (TEPA ) is a slightly viscous liquid and is not colorless but, like many amines, has a yellow color.
Tetraethylenepentamine (TEPA ) is soluble in most polar solvents.
Diethylenetriamine (DETA), triethylenetetramine (TETA), piperazine, and aminoethylpiperazine are also usually present in commercial available Tetraethylenepentamine (TEPA ).

Tetraethylenepentamine (TEPA ) Chemical Properties
Melting point: -40 °C (lit.)
Boiling point: 340 °C
Density: 0.998 g/mL at 25 °C (lit.)
Vapor density: 6.53 (vs air)
Vapor pressure: Refractive index: n20/D 1.505(lit.)
Fp: 365 °F
Storage temp.: Store below +30°C.
Solubility: 6540g/l
Form: Liquid
pka: pK1:2.98(+5);pK2:4.72(+4);pK3:8.08(+3);pK4:9.10(+2);pK5:9.67(+1) (25°C,)
Color: Clear
PH: 11.8 (20g/l, H2O, 20℃)
Odor: ammonia odor
Explosive limit: 0.1-15%(V)
Water Solubility: SOLUBLE
Sensitive: air sensitive
BRN: 506966
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, mineral acids, halogenated hydrocarbons, hydrogen peroxide.
CAS DataBase Reference: 112-57-2(CAS DataBase Reference)
NIST Chemistry Reference: Tetraethylenepentamine (TEPA ) (112-57-2)
EPA Substance Registry System: Tetraethylenepentamine (TEPA ) (112-57-2)

Uses
Solvent for sulfur, acid gases, and various resins and dyes; saponifying agent for acidic materials; manufacture of synthetic rubber; dispersant in motor oils; intermediate for oil additives.
The reactivity and uses of Tetraethylenepentamine (TEPA ) are similar to those for the related ethylene amines ethylenediamine and diethylenetriamine and triethylenetetramine.
Tetraethylenepentamine (TEPA ) is primarily used as a curing agent or hardener in epoxy chemistry.
Tetraethylenepentamine (TEPA ) can be on its own or reacted with tall oil fatty acid (TOFA) and its dimer to make an amidoamine.
This amidoamine is then used as the curing agent for epoxy resin systems.
Tetraethylenepentamine (TEPA ) is a pentadentate ligand in coordination chemistry.

Reactivity Profile
Tetraethylenepentamine (TEPA ) is hygroscopic.
Tetraethylenepentamine (TEPA ) can react with oxidizing materials and strong acids.
Tetraethylenepentamine (TEPA ) may attack some forms of plastics.
Strong irritant to eyes and skin.
Inhalation may cause nausea and slight irritation; compound is a sensitizer, and prolonged contact may cause asthma.
Ingestion can cause burns of mouth, esophagus, and possibly stomach.
Contact with eyes or skin may cause burns. Repeated skin contact may cause dermatitis.

Synonyms
TETRAETHYLENEPENTAMINE
112-57-2
Tetren
1,4,7,10,13-Pentaazatridecane
Tetraethylene pentamine
Tetraethylpentylamine
1,11-Diamino-3,6,9-triazaundecane
DEH 26
3,6,9-Triazaundecane-1,11-diamine
3,6,9-Triazaundecamethylenediamine
Tetrene
Ancamine TEPA
NSC 88603
1,2-Ethanediamine, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
CCRIS 6275
HSDB 5171
EINECS 203-986-2
UN2320
26913-06-4
UNII-YZD1C9KQ28
BRN 0506966
YZD1C9KQ28
AI3-10049
DTXSID7026108
CHEBI:49798
N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine
1,2-Ethanediamine, N-(2-aminoethyl)-N'-(2-((2-aminoethyl)amino)ethyl)-
N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
NSC-88603
NCGC00090964-02
(2-aminoethyl)[2-({2-[(2-aminoethyl)amino]ethyl}amino)ethyl]amine
N-(2-Aminoethyl)-N-(2-((2-aminoethyl)amino)ethyl-1,2-ethanediamine)
Tetraethylenepentamine [UN2320] [Corrosive]
4-04-00-01244 (Beilstein Handbook Reference)
DTXCID006108
TETRAEN
1,2-Ethanediamine, N1-(2-aminoethyl)-N2-(2-((2-aminoethyl)amino)ethyl)-
Bis[2-(2-aminoethylamino)ethyl]amine
n-(2-aminoethyl)-n'-(2-((2-aminoethyl)amino)ethyl)-1,2-ethanediamine
CAS-112-57-2
PAW
BIS(2-(2-AMINOETHYLAMINO)ETHYL)AMINE
Corcat
1,2-Ethanediamine, N1-(2-aminoethyl)-N2-[2-[(2-aminoethyl)amino]ethyl]-
Ttrathylnepentamine
tetraetilenpentamina
Tetraethylenpentamine
MFCD00008168
Texlin 400
tetraethylene pentaamine
1,6,9-triazaundecane
INSULCURE 9
TTP (CHRIS Code)
Tetraethylenepentamine, CP
(C2-H8-N2)mult-
AFR-AN 6
NCIOpen2_001402
SCHEMBL15797
Tetraethylenepentamine (8CI)
WLN: Z2M2M2M2Z
MLS000028888
BIDD:ER0305
CHEMBL138297
1,7,10,13-Pentaazatridecane
3,9-Triazaundecane-1,11-diamine
1 4 7 10 13-Pentaazatridecane
NSC88603
TETRAETHYLENEPENTAMINE [HSDB]
Tox21_111047
Tox21_200669
?1,4,7,10,13-Pentaazatridecane
D.E.H. 26
LS-557
NA2320
STL453738
TH 160
1 11-Diamino-3 6 9-triazaundecane
3 6 9-Triaza-1 11-diaminoundecane
3 6 9-Triazaundecane-1 11-diamine
3,6,9-Triazaundecano-1,11-diamina
AKOS015894482
Tetraethylenepentamine, technical grade
Tox21_111047_1
UN 2320
1,11-diamino-3, 6, 9-triazaundecano
NCGC00090964-01
NCGC00090964-03
NCGC00090964-04
NCGC00258223-01
Poli [imino (1,2-etanodiil)] (9CI)
SMR000059212
FT-0657261
T0098
3,6,9-TRIAZA-1,11-DIAMINOUNDECANE
EN300-268351
Tetraethylenepentamine [UN2320] [Corrosive]
AB00375928_03
UNDECA-1,11-DIAMINE, 3,6,9-TRIAZA-
SR-01000944425
T 11509
T-11509
J-503958
SR-01000944425-1
BRD-K41298358-395-01-8
Q15974770
1, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
1,2-Etanodiamin, N1-(2-aminoetil)-N2-[2-[(2-aminoetil) amino] etil]-
1,2-etanodiamina, N-(2-aminoetil)-N'-[2-[(2-aminoetil) amino] etil]-
1,2-Ethanediamine, N-(2-aminoethyl)-N'-[2-[( 2-aminoethyl)amino]ethyl]-
1,4,7,10,13-Pentaazatrurocano, 3,6,9,-triaza-1,11-diaminoundecano
N-(2-Aminoethyl)-N''''-(2-((2-aminoethyl)amino)ethyl)-1 2-ethanediamine
N1-(2-aminoethyl)-N2-(2-(2-aminoethylamino)ethyl)ethane-1,2-diamine
'N1-{2-[2-(2-AMINO-ETHYLAMINO)-ETHYLAMINO]-ETHYL}-ETHANE-1,2-DIAMINE'
1,2-ETHANEDIAMINE, N-(2-AMINOETHYL)-N'-[2-[(2- AMINOETHYL)AMINO)ETHYL]-
12-Ethanediamine N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-(9CI)

Tetraethylenepentamine (TEPA) is an organic compound and is in the class of chemicals known as ethyleneamines.
Tetraethylenepentamine (TEPA) is a polyazaalkane.


CAS Number: 112-57-2
EC Number: 203-986-2
MDL number: MFCD00008168
Chemical name: N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine
Molecular Formula: C8H23N5 / (NH2CH2CH2NHCH2CH2)2NH


Tetraethylenepentamine (TEPA) appears as a viscous liquid.
Tetraethylenepentamine (TEPA) is slightly less dense than water.
Tetraethylenepentamine (TEPA)'s vapors are heavier than air.
The flashpoint of Tetraethylenepentamine (TEPA) is 325 °F.


Tetraethylenepentamine (TEPA) is a polyazaalkane.
Tetraethylenepentamine (TEPA) has a role as a copper chelator.
Tetraethylenepentamine (TEPA) molar ratio in the mixture to prepare MS-20-4.5 is 4.5, twice over MS-0-2.3.


Tetraethylenepentamine (TEPA) is principally a mixture of four TEPA ethyleneamines with close boiling points including linear, branched, and two cyclic TEPA products, and higher molecular weight products.
The Tetraethylenepentamine (TEPA) market is segmented on the basis of type, application and region.


On the basis of type, the Tetraethylenepentamine (TEPA) market is segmented into 0.993 specific gravity (20/20?), 0.994 specific gravity (20/20?), 0.998 specific gravity (20/20?) and others segments.
The other segment includes products with a specific gravity that falls in between 0.993 and 0.998 inclusive).


On the basis of application, the Tetraethylenepentamine (TEPA) market is classified into chelating agents, polyamide resins, fuel additives surfactants and others segments .
Tetraethylenepentamine (TEPA) is a curing agent for epoxy resins.


Tetraethylenepentamine (TEPA) also functions as a corrosion inhibitor, surfactant and mineral processing aid.
Tetraethylenepentamine (TEPA) is compatible with polyamides.
Tetraethylenepentamine (TEPA) is recommended for coatings.


Tetraethylenepentamine (TEPA) is listed with DSL (Canada) and TSCA (United States).
Tetraethylenepentamine (TEPA) is principally a mixture of four TEPA ethyleneamines with close boiling points including linear, branched, and two cyclic TEPA products, and higher molecular weight products


Tetraethylenepentamine (TEPA) is a viscous hygroscopic liquid.
Tetraethylenepentamine (TEPA) is soluble in most organic solvents and water.
Tetraethylenepentamine (TEPA) is an organic compound and is in the class of chemicals known as ethyleneamines.


Tetraethylenepentamine (TEPA) is a slightly viscous liquid and is not colorless but, like many amines, has a yellow color.
Tetraethylenepentamine (TEPA) is soluble in most polar solvents.
Diethylenetriamine (DETA), Tetraethylenepentamine (TEPA), piperazine, and aminoethylpiperazine are also usually present in commercial available TEPA.


Tetraethylenepentamine (TEPA) is a yellowish liquid containing linear, branched and cyclic molecules.
Tetraethylenepentamine (TEPA) is principally a mixture of four TEPA ethyleneamines with close boiling points including linear, branched, and two cyclic TEPA products, and higher molecular weight products.



USES and APPLICATIONS of TETRAETHYLENEPENTAMINE (TEPA):
Usage of Tetraethylenepentamine (TEPA) asphalt additives, corrosion inhibitors, epoxy curing agents, hydrocarbon purification, lube oil and fuel additives, mineral processing, polyamide resins, surfactants, and textile adhesives.
Tetraethylenepentamine (TEPA) is used in the following applications: Corrosion Inhibitors, Epoxy Curing Agents, Fuel Additives, Hydrocarbon Purification, Ion Exchange Resins, Lube Oil Additives, Paper Wet-Strength Resins, Petroleum Production Chemicals Polyamide Resins, and Surfactants.


Tetraethylenepentamine (TEPA) is used Bitumen Chemicals, Chelating Agents, Corrosion Inhibitors, Epoxy Curing Agents, Industrial Surfactants, Lube Oil and Fuel Additives, Mineral Processing Aids, and Other applications.
Tetraethylenepentamine (TEPA) can be used as a reagent:


To functionalize magnesium 2,5-dihydroxyterephthalate (Mg-MOF-74) to enhance the CO2 adsorption performance of the material.
To modify magnetic chitosan resin to form amine-bearing chitosan for the efficient removal of uranium from an aqueous solution.
To synthesize poly(vinyl-chloride)/tetraethylenepentamine (PVC-Tetraethylenepentamine (TEPA)) composite material, which is used as an efficient catalyst for the Knoevenagel condensation reaction.


The reactivity and uses of Tetraethylenepentamine (TEPA) are similar to those for the related ethylene amines ethylenediamine and diethylenetriamine and triethylenetetramine.
Tetraethylenepentamine (TEPA) is primarily used as a curing agent or hardener in epoxy chemistry.


This can be on its own or reacted with tall oil fatty acid (TOFA) and its dimer to make an amidoamine.
This amidoamine is then used as the curing agent for epoxy resin systems.
Tetraethylenepentamine (TEPA) is a pentadentate ligand in coordination chemistry.


Tetraethylenepentamine (TEPA) is used Asphalt additives, Mineral processing aids, Corrosion inhibitors, Polyamide resins, Epoxy curing agents, Surfactants, Hydrocarbon purification, Textile additives, and Lube oil and fuel additives
Tetraethylenepentamine (TEPA) is used for asphalt additives, mineral processing aids, corrosion inhibitors, polyamide resins, epoxy curing agents, surfactants, hydrocarbon purification, textile additives, lube oil and fuel additives.


Tetraethylenepentamine (TEPA) finds application as an intermediate for the synthesis of coatings and auxillaries and mineral processing aids.
Tetraethylenepentamine (TEPA) is used in the manufacture antistrip additives for asphalt, in epoxy curing agents where it is sometimes used directly, and in lube oil and fuel additives.


Tetraethylenepentamine (TEPA) is used in many applications such as asphalt additives, corrosion inhibitors, epoxy curing agents, hydrocarbon purification, lube oil and fuel additives, mineral processing, polyamide resins, surfactants, and textile adhesives.
Tetraethylenepentamine (TEPA) is commonly used as an additive in fuel and lubricating oil production, as an epoxy curing agent or in the manufacture of asphalt additives.



TETRAETHYLENEPENTAMINE (TEPA) MARKET OVERVIEW:
Tetraethylenepentamine (TEPA) Market size is expected to develop revenue and exponential market growth at a remarkable CAGR during the forecast period from 2023–2030.
The growth of the market can be attributed to the increasing demand for Tetraethylenepentamine (TEPA) owning to the Chelating Agents, Polyamide Resins, Fuel Additives, Surfactants, Others Applications across the global level.



MARKETS OF TETRAETHYLENEPENTAMINE (TEPA):
*Aerospace, Marine and Automotive
*Agriculture
*Construction and Housing
*Household Detergents and Cleaners
*Human and Animal Health Care
*Food
*Industrial Cleaners and Preservants
*Mining
*Personal Care
*Pulp and Paper
*Road Construction
*Textiles and Sports



PHYSICAL and CHEMICAL PROPERTIES of TETRAETHYLENEPENTAMINE (TEPA):
Molecular Weight: 189.30 g/mol
XLogP3-AA: -2.9
Hydrogen Bond Donor Count: 5
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 10
Exact Mass: 189.19534575 g/mol
Monoisotopic Mass: 189.19534575 g/mol
Topological Polar Surface Area: 88.1Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 78.6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C8H23N5
Molar mass: 189.307 g·mol−1
Amine Value, mh KOH/g: 1343
Appearance: Clear amber liquid
Water, wt-%: 0.50 max

Colour, Gardner: 4 max
Boiling Point, 760 mmHg, oC: 332
pH: 11.5
Freezing point oC: 41
Viscosity, cp @20oC: 23.4
Density, g/ml @20oC: 0.991
Specific Gravity, 20/20 oC: 0.993
Physical state: clear, viscous liquid
Color: light yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: -40 °C - lit.
Initial boiling point and boiling range: 340 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 163 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble

Partition coefficient: n-octanol/water: log Pow: 5
Vapor pressure: No data available
Density: 0,998 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Relative vapor density: 6,53 - (Air = 1.0)
HS Code: 2921 29 00
Chemical Name: TRIETHYL ENEPENTAMINE (TEPA)
EINECS No: 203-986-2
Form: Liquid
Density: 0.990 g/cm3
Melting Point: -40 C
Storage: Dry Place
Grade: Industrial Grade
Molecular Weight: 189.307 gmol1
Molecular Formula: C8H23N5
CAS No: 112-57-2
Synonym(s): TEPA, Tetrene
Linear Formula: (NH2CH2CH2NHCH2CH2)2NH

CAS Number: 112-57-2
Molecular Weight: 189.30
Beilstein: 506966
EC Number: 203-986-2
MDL number: MFCD00008168
PubChem Substance ID: 24899938
NACRES: NA.22
vapor density: 6.53 (vs air)
vapor pressure: autoignition temp.: 610 °F
refractive index: n20/D 1.505 (lit.)
bp: 340 °C
mp: −40 °C (lit.)
density: 0.998 g/mL at 25 °C (lit.)
SMILES: string NCCNCCNCCNCCN
InChI: 1S/C8H23N5/c9-1-3-11-5-7-13-8-6-12-4-2-10/h11-13H,1-10H2
InChI key: FAGUFWYHJQFNRV-UHFFFAOYSA-N
Molecular Formula: C8H23N5

Molecular Weight (g/mol): 189.31
MDL Number: MFCD00008168
InChI Key: FAGUFWYHJQFNRV-UHFFFAOYSA-N
PubChem CID: 197
ChEBI: CHEBI:49798
Melting Point: -40°C
Density: 0.9900g/mL
Boiling Point: 340°C
Flash Point: 139°C
Infrared Spectrum: Authentic
Refractive Index: 1.5055
Linear Formula: HN(CH2CH2NHCH2CH2NH2)2
Specific Gravity: 0.99
Solubility Information: Solubility in water: soluble
Formula Weight: 189.3
Percent Purity: ≥95.0%
Physical Form: Liquid
Chemical Name or Material: Tetraethylenepentamine, tech.



FIRST AID MEASURES of TETRAETHYLENEPENTAMINE (TEPA):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water.
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAETHYLENEPENTAMINE (TEPA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TETRAETHYLENEPENTAMINE (TEPA):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAETHYLENEPENTAMINE (TEPA):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 480 min
Splash contact:
Material: Latex gloves
Minimum layer thickness: 0,6 mm
Break through time: 120 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TETRAETHYLENEPENTAMINE (TEPA):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of TETRAETHYLENEPENTAMINE (TEPA):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
TETRAETHYLENEPENTAMINE
112-57-2
Tetren
1,4,7,10,13-Pentaazatridecane
Tetraethylene pentamine
Tetraethylpentylamine
1,11-Diamino-3,6,9-triazaundecane
DEH 26
3,6,9-Triazaundecane-1,11-diamine
3,6,9-Triazaundecamethylenediamine
Tetrene
NSC 88603
1,2-Ethanediamine, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
26913-06-4
YZD1C9KQ28
DTXSID7026108
CHEBI:49798
N'-[2-[2-(2-aminoethylamino)ethylamino]ethyl]ethane-1,2-diamine
1,2-Ethanediamine, N-(2-aminoethyl)-N'-(2-((2-aminoethyl)amino)ethyl)-
N-(2-aminoethyl)-N'-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
NSC-88603
NCGC00090964-02
DTXCID006108
TETRAEN
1,2-Ethanediamine, N1-(2-aminoethyl)-N2-(2-((2-aminoethyl)amino)ethyl)-
n-(2-aminoethyl)-n'-(2-((2-aminoethyl)amino)ethyl)-1,2-ethanediamine
Ancamine TEPA
CAS-112-57-2
PAW
CCRIS 6275
HSDB 5171
EINECS 203-986-2
UN2320
UNII-YZD1C9KQ28
BRN 0506966
AI3-10049
1,2-Ethanediamine, N1-(2-aminoethyl)-N2-[2-[(2-aminoethyl)amino]ethyl]-
Tetraethylenpentamine
MFCD00008168
Texlin 400
tetraethylene pentaamine
1,6,9-triazaundecane
INSULCURE 9
(2-aminoethyl)[2-({2-[(2-aminoethyl)amino]ethyl}amino)ethyl]amine
N-(2-Aminoethyl)-N-(2-((2-aminoethyl)amino)ethyl-1,2-ethanediamine)
Tetraethylenepentamine, CP
Tetraethylenepentamine [UN2320]
NCIOpen2_001402
SCHEMBL15797
WLN: Z2M2M2M2Z
4-04-00-01244 (Beilstein Handbook Reference)
MLS000028888
BIDD:ER0305
CHEMBL138297
1,7,10,13-Pentaazatridecane
Tetraethylenepentamine, tech grade
3,9-Triazaundecane-1,11-diamine
NSC88603
TETRAETHYLENEPENTAMINE
Tox21_111047
Tox21_200669
?1,4,7,10,13-Pentaazatridecane
D.E.H. 26
STL453738
TH 160
AKOS015894482
Tetraethylenepentamine, technical grade
Tox21_111047_1
UN 2320
NCGC00090964-01
NCGC00090964-03
NCGC00090964-04
NCGC00258223-01
SMR000059212
FT-0657261
T0098
3,6,9-TRIAZA-1,11-DIAMINOUNDECANE
BIS(2-(2-AMINOETHYLAMINO)ETHYL)AMINE
EN300-268351
Tetraethylenepentamine [UN2320]
AB00375928_03
SR-01000944425
T-11509
J-503958
SR-01000944425-1
BRD-K41298358-395-01-8
Q15974770
1, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
N1-(2-aminoethyl)-N2-(2-(2-aminoethylamino)ethyl)ethane-1,2-diamine
'N1-{2-[2-(2-AMINO-ETHYLAMINO)-ETHYLAMINO]-ETHYL}-ETHANE-1,2-DIAMINE'
N1-(2-Aminoethyl)-N2-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
TEPA, Tetrene
N1-(2-Aminoethyl)-N2-{2-[(2-aminoethyl)amino]ethyl}ethane-1,2-diamine
1,2-Ethanediamine, N-(2-aminoethyl)-N'-[2-[(2-aminoethyl)amino]ethyl]-
1,11-Diamino-3,6,9-triazaundecane
3,6,9-Triazaundecane-1,11-diamine
Tetraethylenpentamine
3,6,9-Triazaundecamethylenediamine
Tetren
1,4,7,10,13-Pentaazatridecane
D.E.H. 26
UN 2320
TEPA
Texlin 400
1,2-Ethanediamine, N1-(2-aminoethyl)-N2-[2-[(2-aminoethyl)amino]ethyl]-
DEH 26; N-(2-Aminoethyl)-N'-(2-((2-aminoethyl)amino)ethyl)-1,2-ethanediamine
NSC 88603
tetraethylenepentamine
tetren
1,4,7,10,13-pentaazatridecane
tetraethylene pentamine
tetraethylpentylamine
1,11-diamino-3,6,9-triazaundecane
3,6,9-triazaundecamethylenediamine
3,6,9-triazaundecane-1,11-diamine
deh 26
unii-yzd1c9kq28S

Tetraethylthiuram disulfide (TETD), one of the important rubber vulcanization accelerators, can also be applied to prevent fungal diseases and treat alcoholism.
Tetraethylthiuram disulfide (TETD) is a chronic disorder that may have multiple relapses and remissions, increased mortality and low long-term abstinence rates that lead to increased psychosocial losses.
Tetraethylthiuram disulfide (TETD)s ring and chain structures as it is the second only to carbon in exhibiting catenation.

CAS Number: 97-77-8
Molecular Formula: C10H20N2S4
Molecular Weight: 296.54
EINECS Number: 202-607-8

Tetraethylthiuram disulfide (TETD) has been in use since the early 1940s for the treatment of alcohol dependence and is the first FDA-approved medication for the treatment of this disorder.
Tetraethylthiuram disulfide (TETD) has thus completed almost 60 years of use in alcohol use disorders and has stood the test of time.
A large number of studies have been done on this molecule, ever since some proving its superiority over other drugs while others negating it.

Tetraethylthiuram disulfide (TETD) is a chemical compound that belongs to the thiuram disulfide class.
Tetraethylthiuram disulfide (TETD) is used primarily as an accelerator in the vulcanization of rubber, similar to Tetrabenzylthiuram disulfide (TBzTD), which we discussed earlier.
Vulcanization is a process that improves the properties of rubber by cross-linking its polymer chains, making it more durable and elastic.

Tetraethylthiuram disulfide (TETD) is also known by various trade names, including Disulfiram, Antabuse, and others.
Tetraethylthiuram disulfide (TETD) was first synthesized in the 1800s to improve the manufacturing process of rubber.
A physician working in a rubber factory plant first observed in 1937 that factory workers who were exposed to disulfiram were intolerant to ethanol.

In the 1940s, two scientists rediscovered the disulfiram– ethanol effects while researching antiparasitic therapies.
This finding eventually led to the approval of the medication to be used as an ethanol deterrent by the Food and Drug Administration in 1951.
Tetraethylthiuram disulfide (TETD) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.

Tetraethylthiuram disulfide (TETD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells.
Disulfiram + Cu2+ increases intracellular ROS levels triggering apoptosis of ovarian cancer stem cells.
Tetraethylthiuram disulfide (TETD) is a chemical compound used as an accelerator in the rubber industry.

Tetraethylthiuram disulfide (TETD) is also used as a fungicide and pesticide.
Tetraethylthiuram disulfide (TETD) has a purity of 97% and comes in a package size of 250g.
Tetraethylthiuram disulfide (TETD) should be handled with care, as it can cause skin and eye irritation upon contact.

Tetraethylthiuram disulfide (TETD) should be stored in a cool, dry place away from sources of heat or ignition.
Environmental impact information shows that Tetraethylthiuram disulfide (TETD) may be harmful to aquatic life if released into waterways, so proper disposal methods must be followed according to local regulations.
Some pharmaceutical grade of thiocarbamate derivatives such as Tetraethylthiuram disulfide (TETD) are used in the treatments of chronic alcoholism by inhibiting aldehyde dehydrogenase, a breakdown product of alcohol, to accumulate in the blood.

Tetraethylthiuram disulfide (TETD) is also being studied as a treatment for cocaine dependence, as it prevents the breakdown of dopamine and several studies have reported that it has anti-protozoal activity as well.
Tetraethylthiuram disulfide (TETD) is a peptizing agent in sulfur-modified polychloroprenes.
Tetraethylthiuram disulfide (TETD)s such as Ziram and Zineb are also used as a fungicide, seed disinfectant, bactericide and insecticide.

Tetraethylthiuram disulfide (TETD)s with nearly all elements.
The 8-membered ring and shorter chain structure of sulfur molecule is important in vulcanization process which individual polymers are linked to other polymer molecules by atomic bridges.
Many drugs have been used in the treatment of this disorder such as the anti-craving agents, acamprosate, naltrexone and the aversive agent, Tetraethylthiuram disulfide (TETD).

This process produces thermoset materials which are cross-linked and irreversible substances.
The term thermoplastic is for high molecular weight polymers which can undergo melting-freezing cycle.
Thermosets are not melted and re-molded on heating after cured.

The split of sulfur 8-membered ring structure into shorter chains provides rubber vulcanization process.
The split are liked with cure sites (some of the solid bonds in the molecule) on rubber molecules, resulting in forming sulfur bridges typically between 2 and 10 atoms long.
Vulcanization makes rubber harder, more durable and more resistant to heating, aging and chemical attacks.

The number of sulfur atoms in the sulfur bridges varies physical properties of the end products.
Short bridges containing one or two sulfur atoms offer heat resistance and long bridges offer flexible property.
Vulcanization can also be accomplished with certain peroxides, gamma radiation, and several other organic compounds.

The principal classes of peroxide cross-linking agents are dialkyl and diaralkyl peroxides, peroxyketals and peroxyesters.
Other vulcanizing agents include amine compounds for the cross-linking of fluorocarbon rubbers, metal oxides for chlorine-containing rubbers (notably zinc oxide for chloroprene rubber) and phenol-formaldehyde resins for the production of heat-resistant butyl rubber vulcanizates.
Accelerator, in the Tetraethylthiuram disulfide (TETD), is added with a curing agent to speed the vulcanization.

Accelerators contain sulfur and nitrogen like derivatives of benzothiazole and Tetraethylthiuram disulfide (TETD).
The popular accelerators are sulfenamides (as a delayed-action accelerators), thiazoles, thiuram sulfides, dithocarbamates and guanidines.
Tetraethylthiuram disulfide (TETD) may be made by the reaction of diethyl amine with carbon disulfide in the presence of sodium hydroxide.

The (C2H5)2NCSSNa intermediate is oxidatively coupled using hydrogen peroxide to give Tetraethylthiuram disulfide (TETD).
Tetraethylthiuram disulfide (TETD)s are a class of organosulfur compounds with the formula (R2NCSS)2.
Many examples are known, but popular ones include R = Me and R = Et. They are disulfides obtained by oxidation of the dithiocarbamates.

Tetraethylthiuram disulfide (TETD)s are used in sulfur vulcanization of rubber as well as in the manufacture of pesticides and drugs.
They are typically white or pale yellow solids that are soluble in organic solvents.
Tetraethylthiuram disulfide (TETD) is an oral drug used for treating alcoholism.

Alcohol is converted in the body into acetaldehyde by an enzyme called alcohol dehydrogenase.
Another enzyme called acetaldehyde dehydrogenase then converts acetaldehyde into acetic acid.
Tetraethylthiuram disulfide (TETD) prevents acetaldehyde dehydrogenase from converting acetaldehyde into acetic acid, leading to a buildup of acetaldehyde levels in the blood.

Tetraethylthiuram disulfide (TETD) is tested in the standard allergen tray as one of the components of the thiuram mix (tetraethylthiuram disulfide); Thiuram-sensitive patients who take Antabuse may develop a generalized contact dermatitis or localized hand and foot dermatitis.
A nurse dispensing Tetraethylthiuram disulfide (TETD) developed contact dermatitis; Drug-induced hepatitis has been rarely reported in patients taking therapeutic doses of Antabuse.

Poisoning by ingestion (with alcohol): headache, flushing, hypotension, sweating, dizziness, nausea, vomiting, and diarrhea; Poisoning by ingestion (acute overdose): delirium, agitation, CNS depression; Poisoning by ingestion (chronic overdose): encephalopathy and neuropathy.

In severe cases, hepatitis such as both cholestatic and fulminant hepatitis, as well as hepatic failure resulting in transplantation or death, could occur upon treatment of disulfiram.
In a small number of patients, side effects include a transient mild drowsiness, fatigability, impotence, headache, acneform eruptions, allergic dermatitis, or a metallic or garlic-like aftertaste during the first two weeks of therapy.
These reactions often disappear spontaneously with the continuation of therapy, or with reduced dosage.

High dosage, combined toxicity (with metronidazole or isoniazid), or to the unmasking of underlying psychoses can cause psychotic reactions.
Tetraethylthiuram disulfide (TETD) irreversibly inhibits aldehyde dehydrogenase, which prevents the oxidation of alcohol after the acetaldehyde stage.
Tetraethylthiuram disulfide (TETD) interacts with ingested alcohol to produce acetaldehyde levels five to ten times higher than are produced by normal alcohol metabolism.

Excess acetaldehyde produces a highly unpleasant reaction (nausea and vomiting) to even a small quantity of alcohol.
Tolerance to disulfiram doesn’t occur; rather, sensitivity to alcohol increases with longer duration of therapy.
Tetraethylthiuram disulfide (TETD) offers fast vulcanization and gives more scorch delay than Dimacit TMTD.

Tetraethylthiuram disulfide (TETD) gives an excellent vulcanization plateau with good heat aging and compression set resistance when used in sulfur less vulcanization systems and EV systems.
Tetraethylthiuram disulfide (TETD) is a valuable secondary accelerator.
Tetraethylthiuram disulfide (TETD) gives excellent dispersions in soft compounds due to its low melting point.

Tetraethylthiuram disulfide (TETD) is non-staining and non-discoloring; excellent colors are obtained in non-black vulcanizates.
Tetraethylthiuram disulfide (TETD)s are prepared by oxidizing the salts of the corresponding dithiocarbamates (e.g. sodium diethyldithiocarbamate).
Typical oxidants employed include chlorine and hydrogen peroxide:
2 R2NCSSNa + Cl2 → (R2NCSS)2 + 2 NaCl

Tetraethylthiuram disulfide (TETD)s react with Grignard reagents to give esters of dithiocarbamic acid, as in the preparation of methyl dimethyldithiocarbamate:
[Me2NC(S)S]2 + MeMgX → Me2NC(S)SMe + Me2NCS2MgX
Tetraethylthiuram disulfide (TETD)s feature planar dithiocarbamate subunits and are linked by an S−S bond of 2.00 Å. The C(S)−N bond is short (1.33 Å), indicative of multiple bonding.

The dihedral angle between the two dithiocarbamate subunits approaches 90°.
Tetraethylthiuram disulfide (TETD)s are weak oxidants.
They can be reduced to dithiocarbamates.

Treatment of a Tetraethylthiuram disulfide (TETD) with triphenylphosphine, or with cyanide salts, yields the corresponding thiuram sulfide:
(R2NCSS)2 + PPh3 → (R2NCS)2S + SPPh3
Chlorination of thiuram disulfide affords the thiocarbamoyl chloride.

Tetraethylthiuram disulfide (TETD) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1).
Tetraethylthiuram disulfide (TETD) is used in the study of chronic alcoholism, with acute sensitivity to alcohol, and is a potent copper ion-carrier that can be used in cuproptosis studies.
Tetraethylthiuram disulfide (TETD) inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells.

Tetraethylthiuram disulfide (TETD) + Cu2+ increases intracellular ROS levels triggering apoptosis of ovarian cancer stem cells.

Tetraethylthiuram disulfide (TETD) has a molecular weight of approximately 296.54 g/mol.
Tetraethylthiuram disulfide (TETD) is commonly found as a white to light yellow crystalline powder.
Tetraethylthiuram disulfide (TETD) is sparingly soluble in water but dissolves in organic solvents such as ethanol and acetone.

Similar to other thiuram disulfides, Tetraethylthiuram disulfide (TETD) plays a crucial role in the vulcanization of rubber.
During vulcanization, Tetraethylthiuram disulfide (TETD) reacts with sulfur and the polymer chains of rubber, forming cross-links that improve the strength, elasticity, and other mechanical properties of the rubber.
Tetraethylthiuram disulfide (TETD) is known for its relatively slow rate of vulcanization.

This characteristic can be advantageous in certain rubber processing applications where a delayed onset of vulcanization is desirable.
Tetraethylthiuram disulfide (TETD), a pharmaceutical drug used to treat chronic alcoholism, is derived from Tetraethylthiuram disulfide (TETD).
Tetraethylthiuram disulfide (TETD) works by inhibiting the enzyme acetaldehyde dehydrogenase, leading to the accumulation of acetaldehyde in the body when alcohol is consumed.

This results in adverse reactions such as nausea, vomiting, and flushing, discouraging the individual from drinking alcohol.
Workers involved in the production and handling of TETD should adhere to safety protocols, including the use of appropriate personal protective equipment (PPE) such as gloves and goggles, to minimize the risk of skin and eye irritation.
Tetraethylthiuram disulfide (TETD), like other chemical compounds, is subject to regulatory oversight.

Tetraethylthiuram disulfide (TETD) users and manufacturers should be aware of and comply with regulations governing its production, storage, transportation, and disposal.
Tetraethylthiuram disulfide (TETD) has been widely used as a rubber accelerator, ongoing research and developments in the rubber industry may lead to the discovery of new accelerators or improvements in existing ones.
The industry may explore alternatives for reasons such as environmental impact, performance, and safety.

Melting point: 69-71 °C (lit.)
Boiling point: 117°C
Density: 1.27
vapor pressure: 0Pa at 25℃
refractive index: 1.5500 (estimate)
Flash point: 117°C/17mm
storage temp.: 2-8°C
solubility: 0.004g/l
form: Crystals, Crystalline Powder or Granules
pka: 0.86±0.50(Predicted)
color: Light yellow
Odor: lt. gray powd., sl. odor
Water Solubility: 0.02 g/100 mL
Merck: 14,3364
BRN: 1712560
Exposure limits ACGIH: TWA 2 mg/m3
NIOSH: TWA 2 mg/m3
Stability: Stable. Incompatible with strong oxidants.
InChIKey: AUZONCFQVSMFAP-UHFFFAOYSA-N
LogP: 3.6 at 21℃

Tetraethylthiuram disulfide (TETD) undergoes metabolism in the liver initially by alcohol dehydrogenase (ADH) forming acetaldehyde; this is removed from the body primarily by oxidation into acetate by acetaldehyde dehydrogenase (ALDH), which finally enters the citric acid cycle.
Tetraethylthiuram disulfide (TETD) acts by inhibiting the enzyme ALDH via its metabolite S-methyl N, N-diethyl-dithio-carbamate-sulphoxide, leading to accumulation of acetaldehyde in blood.
This gives rise to various manifestations of disulfiram-alcohol reaction (DER).

Since the inhibition of ALDH by disulfiram is irreversible, the DER will get terminated only after production of new ALDH oncedisulfiram is stopped.
The new ALDH takes about a week’s time to be produced.
Hence patients should be advised to take alcohol only after 2 weeks of stopping disulfiram.

In addition to this, Tetraethylthiuram disulfide (TETD) also acts on the dopaminergic system, both disulfiram and its metabolite carbon disulfide leading to inhibition of dopamine beta-hydroxylase (DBH) that leads to increase in the levels of dopamine.
This may give rise to several neuropsychiatric manifestations such as delirium, paranoia, impairment of memory, ataxia, dysarthria and frontal lobe release signs.
Besides this action, disulfiram is also known to inhibit dopamine beta-hydroxylase leading to an increase in dopamine concentrations but decreased norepinephrine in the brain.

This may suggest an anti-craving role of disulfiram in alcohol dependence.
Tetraethylthiuram disulfide (TETD) is used as a second line treatment of alcohol dependence, behind acamprosate and naltrexone.
Tetraethylthiuram disulfide (TETD) is an aid for the management of selected chronic alcohol patients who want to remain in a state of enforced sobriety so that supportive and psychotherapeutic treatment may be applied to best advantage.

Tetraethylthiuram disulfide (TETD) should be noted that disulfiram is not a cure for alcoholism.
When used alone, without proper motivation and supportive therapy, it is unlikely that it will have any substantive effect on the drinking pattern of the chronic alcoholic dependence.
Tetraethylthiuram disulfide (TETD) should not be taken if alcohol has been consumed in the last 12 hours.

Recently, more and more studies have shown that Tetraethylthiuram disulfide (TETD) has the potential for the treatment of cancer and HIV infections.
Tetraethylthiuram disulfide (TETD) can reactivate latent HIV-1 expression in a primary cell model of virus latency and has the potential to deplete the latent HIV-1 reservoir in patients on combination antiretroviral therapy.
Tetraethylthiuram disulfide (TETD) can reactivate latent HIV-1 expression via the Akt signaling pathway through depletion of PTEN.

Recent studies have disclosed a surprising, but mechanistically consistent, anticancer activity of disulfiram.
Tetraethylthiuram disulfide (TETD) has been successfully used to suppress hepatic metastases originating from ocular melanoma.
The anticancer mechanism of Tetraethylthiuram disulfide (TETD) is through inhibiting the 26S proteasome (The orderly degradation of cellular proteins is critical for normal cell cycling and function, and inhibition of the proteasome pathway results in cell-cycle arrest and apoptosis).

Tetraethylthiuram disulfide (TETD) was also found to have specific activity against zinc fingers and RING-finger ubiquitin E3 ligases that play an important role in cancer development.
Tetraethylthiuram disulfide (TETD) is not allowed if the patients have consumed alcohol within the past 12 hours.
Tetraethylthiuram disulfide (TETD) is not known whether disulfiram will harm an unborn baby.

Tetraethylthiuram disulfide (TETD) is not known whether disulfiram passes into breast milk or if it could harm a nursing baby.
Tetraethylthiuram disulfide (TETD) should not be used in the following cases:
Allergic people; those who have recently taken metronidazole (Flagyl) or paraldehyde; or have consumed any foods or products that contain alcohol; People of the following cases should consult the doctors.

Liver or kidney disease; heart disease, high blood pressure, history of heart attack or stroke.
Underactive thyroid; diabetes; seizures or epilepsy; head injury or brain damage; a history of mental illness or psychosis; an allergy to rubber; or taking phenytoin (Dilantin), tuberculosis medicine, or a blood thinner (warfarin, Coumadin, Jantoven).
Tetraethylthiuram disulfide (TETD) is valued for its ability to efficiently promote cross-linking in rubber, leading to improved properties such as elasticity, strength, and resistance to wear and aging.

The curing or vulcanization time of rubber formulations containing Tetraethylthiuram disulfide (TETD) can be influenced by its concentration.
Rubber manufacturers may adjust the accelerator dosage to achieve the desired curing times in their production processes.
Tetraethylthiuram disulfide (TETD) is compatible with various rubber polymers, including natural rubber and synthetic rubbers like styrene-butadiene rubber (SBR) and butadiene rubber (BR).

This versatility makes it suitable for a wide range of rubber applications.
Tetraethylthiuram disulfide (TETD) should be stored under specific conditions to maintain its stability.
Like many chemical compounds, exposure to factors such as heat, moisture, and incompatible substances should be minimized to prevent degradation.

Tetraethylthiuram disulfide (TETD) may cause adverse health effects. Inhalation, skin contact, or ingestion should be avoided, and proper safety measures, including the use of protective equipment, should be employed to minimize the risk of exposure.
Tetraethylthiuram disulfide (TETD), it's essential to follow recommended handling precautions, including wearing appropriate protective clothing, using adequate ventilation, and avoiding contact with eyes, skin, and clothing.
Understanding the environmental fate of Tetraethylthiuram disulfide (TETD) is crucial for responsible use.

This includes considerations for its potential persistence, bioaccumulation, and toxicity in the environment.
Proper disposal practices should be followed to prevent environmental contamination.
Analytical techniques are employed to monitor the presence of Tetraethylthiuram disulfide (TETD) in various stages of rubber processing and in the final products.

These techniques help ensure that Tetraethylthiuram disulfide (TETD) is used within specified limits and that the resulting rubber products meet quality standards.
Ongoing research may focus on optimizing the performance of Tetraethylthiuram disulfide (TETD) in rubber formulations, exploring new applications, and addressing potential environmental and health concerns associated with its use.
Tetraethylthiuram disulfide (TETD), like other chemical compounds, is part of the global trade and supply chain.

Factors such as market demand, trade regulations, and geopolitical considerations can influence its availability and use.
Quality control measures are essential in rubber manufacturing to ensure that Tetraethylthiuram disulfide (TETD) and other additives are used in appropriate concentrations.
Monitoring and testing during the production process help maintain consistent product quality.

Tetraethylthiuram disulfide (TETD) can influence the cure characteristics of rubber compounds.
The choice of accelerator, including Tetraethylthiuram disulfide (TETD), can affect parameters such as scorch time, cure time, and cure rate, which are critical factors in rubber processing.
Tetraethylthiuram disulfide (TETD), as an accelerator, may influence the adhesion properties of vulcanized rubber.

The adhesion of rubber to various substrates is an important consideration in applications such as tire manufacturing.
Rubber formulations often use a combination of accelerators, including Tetraethylthiuram disulfide (TETD), to achieve synergistic effects.
The combination of different accelerators can enhance vulcanization efficiency and improve specific properties of the rubber.

Tetraethylthiuram disulfide (TETD) is typically incorporated into rubber compounds during the compounding stage.
Rubber compounders carefully select and balance various ingredients, including accelerators, to achieve the desired properties in the final product.
Tetraethylthiuram disulfide (TETD) play a role in modifying the properties of rubber polymers.

This modification is essential for tailoring rubber formulations to meet specific performance requirements in diverse applications.
Tetraethylthiuram disulfide (TETD) are influenced by global trends in the rubber industry.
Shifts in demand for rubber products, such as tires, impact the use of TETD in various regions.

Tetraethylthiuram disulfide (TETD) is part of the supply chain logistics in the rubber industry.
Efficient transportation, storage, and distribution practices are critical to ensuring a stable supply of Tetraethylthiuram disulfide (TETD) for manufacturers.
As with many additives in rubber, considerations about the recyclability of rubber products containing Tetraethylthiuram disulfide (TETD) are important.

The impact of accelerators on the recycling process and the development of sustainable practices in the rubber industry are areas of ongoing research.
Tetraethylthiuram disulfide (TETD) should be monitored in workplaces where it is used.
Regular assessment of workplace air quality and adherence to occupational exposure limits help protect the health and safety of workers.

Ongoing research explores new technologies and innovations in rubber processing.
These advancements may lead to the development of novel accelerators or improvements in the performance of existing ones, including Tetraethylthiuram disulfide (TETD).

Uses:
Tetraethylthiuram disulfide (TETD) , is a sulfur- and nitrogen-containing compound with several industrial uses, including applications as a rubber accelerator and vulcanizer, fungicide, and seed disinfectant.
Tetraethylthiuram disulfide (TETD) is most commonly known as antabuse, a therapeutic agent for the treatment of alcohol abuse that causes nausea, vomiting, and other adverse effects when ethanol is ingested. Disulfiram is an inhibitor of aldehyde dehydrogenase so that it allows for buildup of the acetaldehyde metabolite of ethanol, causing unpleasant effects that are a deterrent to the ingestion of alcohol.
Because of the buildup of acetaldehyde, disulfiram should be given with extreme caution, especially to individuals suffering from liver cirrhosis.

Tetraethylthiuram disulfide (TETD) is used as an accelerator, activator, stabilizer and vulcanizing agent for various rubber products.
Tetraethylthiuram disulfide (TETD) is also used as a fungicide, seed disinfectant and in medicines used in the treatment of alcoholism.
Further research may identify additional product or industrial usages of this chemical.

Tetraethylthiuram disulfide (TETD) is found in drugs used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
Tetraethylthiuram disulfide (TETD), is a widely used fungicide. The tetraethyl derivative, known as disulfiram, is commonly used to treat chronic alcoholism.
Tetraethylthiuram disulfide (TETD) produces an acute sensitivity to alcohol ingestion by blocking metabolism of acetaldehyde by acetaldehyde dehydrogenase, leading to a higher concentration of the aldehyde in the blood, which in turn produces symptoms of a severe hangover.

Tetraethylthiuram disulfide (TETD) is primarily used as an accelerator in the vulcanization process of rubber.
Tetraethylthiuram disulfide (TETD) promotes the formation of cross-links between polymer chains, leading to the improvement of rubber's mechanical properties.
Tetraethylthiuram disulfide (TETD) is commonly used in the production of tires to enhance their performance characteristics.

Tetraethylthiuram disulfide (TETD) contributes to the vulcanization process, ensuring that the rubber in tires becomes more durable, heat-resistant, and able to maintain its shape under various conditions.
Tetraethylthiuram disulfide (TETD) is also utilized in the manufacturing of various rubber products such as conveyor belts, hoses, seals, gaskets, and other industrial and consumer goods.
Tetraethylthiuram disulfide (TETD) is role in vulcanization improves the overall quality and longevity of these rubber items.

Tetraethylthiuram disulfide (TETD), like other accelerators, can be included in adhesive and sealant formulations where vulcanization or curing of rubber is required.
This helps improve the adhesive properties and durability of the final product.
Tetraethylthiuram disulfide (TETD) may find application in the plastics industry where it is used as a cross-linking agent for certain types of elastomers or polymer blends, contributing to improved physical properties.

Tetraethylthiuram disulfide (TETD) may be employed in the vulcanization of specialty rubbers, such as ethylene propylene diene monomer (EPDM) rubber, which is commonly used in automotive parts, electrical insulation, and roofing materials.
The choice of accelerator depends on the specific rubber formulation and its intended application.
Tetraethylthiuram disulfide (TETD) can be used in the curing of latex compounds.

Latex is a dispersion of rubber particles in water, and Tetraethylthiuram disulfide (TETD), as an accelerator, can aid in the vulcanization process of latex-based products, including certain types of adhesives and coatings.
In the field of rubber and polymer science, Tetraethylthiuram disulfide (TETD) may be used in research and development to study its effects on vulcanization kinetics, cross-linking efficiency, and the properties of the resulting materials.
Researchers may explore variations in formulations to optimize performance in specific applications.

Tetraethylthiuram disulfide (TETD) is sometimes used in combination with other accelerators, such as thiurams, sulfenamides, and dithiocarbamates, to achieve synergistic effects and fine-tune the vulcanization process.
The combination of accelerators allows rubber manufacturers to tailor the curing characteristics to meet specific requirements.
As with other accelerators, the use of Tetraethylthiuram disulfide (TETD) may be influenced by regulatory requirements and environmental considerations.

Rubber manufacturers may adjust formulations to comply with evolving regulations and to meet industry standards for sustainability and safety.
Tetraethylthiuram disulfide (TETD) is mainly known for its use in the rubber industry, its derivative, disulfiram, is used in medicine. Disulfiram is used as a medication to treat chronic alcoholism.
Tetraethylthiuram disulfide (TETD) works by inhibiting the enzyme acetaldehyde dehydrogenase, leading to the accumulation of acetaldehyde in the body when alcohol is consumed.

This results in unpleasant reactions, discouraging individuals from drinking alcohol.
Tetraethylthiuram disulfide (TETD) is known as a delayed-action accelerator, meaning it has a slower rate of vulcanization compared to some other accelerators.
This characteristic can be advantageous in certain rubber processing applications where a controlled and delayed onset of vulcanization is desired.

In addition to its use in rubber, Tetraethylthiuram disulfide (TETD) has found applications in the textile industry, where it can be used in certain processes related to the treatment of textiles and fabrics.
Tetraethylthiuram disulfide (TETD) may be incorporated into rubber formulations used for wire and cable insulation.
The vulcanization process ensures that the rubber insulation maintains its integrity under various conditions, providing electrical insulation properties.

In some formulations for foam rubber products, Tetraethylthiuram disulfide (TETD) may be used as an accelerator to enhance the curing process and improve the physical properties of the foam, such as resilience and elasticity.
Tetraethylthiuram disulfide (TETD) is often compatible with oil-extended rubbers, where rubber compounds are extended or reinforced with oils.
This compatibility allows for versatility in formulating rubber compounds for various applications.

Rubber formulators may choose Tetraethylthiuram disulfide (TETD) based on its compatibility with specific rubber types, processing conditions, and the desired properties of the final rubber product.
The selection of accelerators is a critical aspect of rubber compounding.
Tetraethylthiuram disulfide (TETD) formulations, like other rubber compounds, should be stored under appropriate conditions to maintain stability.

Adequate storage practices help ensure that the accelerator retains its effectiveness during the shelf life of the rubber product.
Rubber manufacturers carefully evaluate the cure characteristics of formulations containing Tetraethylthiuram disulfide (TETD).
This includes monitoring parameters such as scorch time, cure time, and cure rate to optimize the vulcanization process and ensure consistency in product quality.

Tetraethylthiuram disulfide (TETD) is part of the global trade in rubber chemicals.
Tetraethylthiuram disulfide (TETD) is availability and usage are influenced by factors such as market demand, economic conditions, and trade agreements.
Tetraethylthiuram disulfide (TETD) is a copper and zinc chelator and an irreversible inhibitor of aldehyde dehydrogenase (IC50 = 0.1 mM) that has been indicated for the treatment of alcohol dependence.

Tetraethylthiuram disulfide (TETD) also inhibits the copper-dependent enzyme dopamine β-hydroxylase, which prevents the breakdown of dopamine and has been considered as a treatment for cocaine dependence.
When in complex with copper, Tetraethylthiuram disulfide (TETD) has been shown to inhibit purified 20S proteasome (IC50 = 7.5 μM) and 26S proteasome (IC50 = 20 μM) from MDA-MB-0231 breast cancer cells.

Because Tetraethylthiuram disulfide (TETD) targets the ubiquitin-proteasome pathway, it has been investigated as an anti-cancer agent.
Furthermore, at 250 nM it has been shown to induce reactive oxygen species, to activate JNK and p38 pathways, and to inhibit NF-κB activity, which suppresses self-renewal in cancer stem cells.

Metabolism:
Tetraethylthiuram disulfide (TETD) is rapidly reduced to diethyldithiocarbamate, mainly by the glutathione reductase system in erythrocytes; reduction may also occur in the liver.
Tetraethylthiuram disulfide (TETD) is metabolised in the liver to its glucuronide and methyl ester and to diethylamine, carbon disulfide, and sulfate ions.
Tetraethylthiuram disulfide (TETD) are excreted mainly in the urine; carbon disulfide is exhaled in the breath.

Toxicity evaluation
Disulfiram has multiple mechanisms of toxicity. Its most welldefined action is inhibition of aldehyde dehydrogenase, which thereby diminishes the breakdown of acetaldehyde. Accumulation of carbon disulfide, a disulfiram metabolite, as well as inhibition of dopamine-b-hydroxylase has also been associated with its toxicity in particular related to use for cocaine dependence.

Safety Profile:
Tetraethylthiuram disulfide (TETD) a human poison by ingestion.
An experimental poison by intraperitoneal route.
Toxic symptoms when accompanied by ingestion of alcohol.

Human systemic effects by ingestion: jaundtce, joint changes.
Other experimental reproductive effects.
Questionable carcinogen with experimental neoplastigenic data.

Tetraethylthiuram disulfide (TETD), like many chemical compounds, should be handled with care.
Tetraethylthiuram disulfide (TETD) can pose health hazards, including skin and eye irritation, and proper safety precautions, including the use of personal protective equipment, should be followed.

Health Hazard:
Tetraethylthiuram disulfide (TETD) affects the central nervous system, thyroid, and skin; in combination with alcohol it causes an “Antabusealcohol” syndrome.
Small doses of Tetraethylthiuram disulfide (TETD) reportedly can cause effects on thyroid iodine uptake and thyroid gland hypertrophy.
Tetraethylthiuram disulfide (TETD) may also produce dermatitis and acneform rashes.

Synonyms:
2-Cyano-4-phenylpyridine
4-phenylpyridine-2-carbonitrile
18714-16-4
4-Phenylpicolinonitrile
4-Phenyl-2-pyridinecarbonitrile
2-Pyridinecarbonitrile,4-phenyl-
2-Pyridinecarbonitrile, 4-phenyl-
SCHEMBL317097
DTXSID0066400
4-phenyl-pyridine-2-carbonitrile
tetraethylthiuram disulfide (tetd)
TXLINXBIWJYFNR-UHFFFAOYSA-N
AKOS023880231
4-Phenylpyridine-2-carbonitrile, 97%
TS-02524
CS-0333761
FT-0720248
A1-20075
J-012039

THF; Tetramethylene oxide; Oxolane; Butylene oxide; Cyclotetramethylene oxide; Furanidine; 1,4-Epoxy-Butane;Oxacyclopentane; Oxolane; Tetrahydrofuran; Tetramethylene oxide; Diethylene oxide; Hydrofuran; Tetrahydrofuraan; Tetrahydrofuranne; Tetraidrofurano CAS NO: 109-99-9

cis-4-cyclohexene-1,2-dicarboxylic anhydride; 1,2,3,6-tetrahydrophthalic acid anhydride; 1,2,3,6-tetrahydrophthalicacidanhydride; 1,2,3,6-tetrahydro-phthalicanhydrid; 1,3-isobenzofurandione, 3a,4,7,7a-tetrahydro-, cis-; 1,3-isobenzofurandione,3a,4,7,7a-tetrahydro-; 3a,4,7,7a-tetrahydro-1,3-benzofurandione; 3a,4,7,7a-tetrahydro-3-isobenzofurandione CAS NO: 85-43-8

DESCRIPTION:
Tetrahydrofurfuryl alcohol (THFA) is an organic compound with the formula HOCH2C4H7O.
In terms of its structure, Tetrahydrofurfuryl alcohol consists of a tetrahydrofuran ring substituted in the 2-position with a hydroxymethyl group.
Tetrahydrofurfuryl alcohol is a colorless liquid that is used as a specialty solvent and synthetic intermediate, e.g. to 3,4-dihydropyran.

CAS Number: 97-99-4
EC Number: 202-625-6
Molar Mass: 102.13 g/mol
Hill Formula: C₅H₁₀O₂
Preferred IUPAC name: (Oxolan-2-yl)methanol

Tetrahydrofurfuryl alcohol is prepared by hydrogenation of furfural.
Tetrahydrofurfuryl alcohol is a precursor to 1,5-pentanediol.
Tetrahydrofurfuryl alcohol undergoes chemoselective hydrogenolysis catalyzed by Rh/SiO2 modified with ReOx species to yield 1,5-pentanediol.

Tetrahydrofurfuryl alcohol undergoes lanthanum-mediated Michael-type addition reaction with maleate to form alkoxybutanedioic acid.
Tetrahydrofurfuryl alcohol appears as a clear colorless liquid with a mild odor.
Vapors of Tetrahydrofurfuryl alcohol are heavier than air.
Tetrahydrofurfuryl alcohol is a primary alcohol that is methanol in which one of the hydrogens of the methyl group has been replaced by a tetrahydrofuran-2-yl group.

Tetrahydrofurfuryl alcohol has a role as a protic solvent.
Tetrahydrofurfuryl alcohol is a primary alcohol and a member of oxolanes.
Tetrahydrofurfuryl alcohol is a natural product found in Mangifera indica with data available.
Tetrahydrofurfuryl alcohol is produced commercially by catalytic hydrogenation of furfuryl alcohol using the Nickel based catalyst of high activity and selectivity.
THFA has a purity of 98.5%.

Tetrahydrofurfuryl alcohol is a clear, colorless liquid.
Tetrahydrofurfuryl alcohol has a boiling point of 176 °C and a flash point of -40 °C.
Tetrahydrofurfuryl alcohol is soluble in water and glycol ethers.

Tetrahydrofurfuryl alcohol is used as an industrial solvent for paints, dyes, lacquers, varnishes, and other coatings.
Tetrahydrofurfuryl alcohol also serves as an excellent catalyst for hydrogenation reactions.
The use of tetrahydrofurfuryl alcohol as a catalyst for the hydrogenation of unsaturated hydrocarbons to produce saturated compounds is well known.

Tetrahydrofurfuryl alcohol may be injected into the body to treat conditions such as epilepsy and depression.
Tetrahydrofurfuryl alcohol can also be used as a transfer reagent in organic synthesis reactions that require transfer of the tetra-hydro-group from one reactant to another.



USES OF TETRAHYDROFURFURYL ALCOHOL:
Tetrahydrofurfuryl alcohol is often used in epoxy resin formulations in either the epoxy component or amine hardener as well as other general resin applications
Tetrahydrofurfuryl alcohol was used as refractive-index matching solvent to ensure hard sphere suspension of silica particles for rheological measurements.

Tetrahydrofurfuryl alcohol is a low cost, biodegradable solvent mainly used as a reactive diluent for epoxy resins and is a good solvent for many of the curative and catalysts used in epoxy formulations.
Tetrahydrofurfuryl alcohol will accelerate the cure of Bisphenol, resins with either aliphatic or aromatic amine curative.
Tetrahydrofurfuryl alcohol is also used in the following applications:
Tetrahydrofurfuryl alcohol is used in Biocide and pesticide formulations.
Tetrahydrofurfuryl alcohol is used in Stripping formulations.

Tetrahydrofurfuryl alcohol is used in Electronic cleaner formulations.
Tetrahydrofurfuryl alcohol is used in Coatings, dyes and printing ink.
Tetrahydrofurfuryl alcohol is used in Epoxy curing agent.

Tetrahydrofurfuryl alcohol (CAS 97-99-4) is a biomass-based solvent produced via catalytic hydrogenation of furfuryl alcohol.
As a solvent, Tetrahydrofurfuryl alcohol is used in agrochemical formulations, cleaning products, metal-working fluids and coating/paint stripper formulations.
Tetrahydrofurfuryl alcohol is biodegradable and water-soluble and does have a low vapor pressure and has excellent solvable properties.
Tetrahydrofurfuryl alcohol is also used as a chemical intermediate.

APPLICATIONS OF TETRAHYDROFURFURYL ALCOHOL:

Tetrahydrofurfuryl alcohol is a furfural derivative obtained by catalytic hydrogenation.
Tetrahydrofurfuryl alcohol has many applications in various industries.
For example, Tetrahydrofurfuryl alcohol is used as an environmentally benign, biodegradable, water-miscible solvent for agrochemical formulations (biocides, pesticides, fungicides, herbicides), cleaning products, dyes and resins, and as an ingredient for polymers and resins, lacquers, pharmaceuticals and specialty chemicals, and adhesive formulations.

Tetrahydrofurfuryl alcohol is Used as (cleaning) solvent, a.o. in electronics industry
Tetrahydrofurfuryl alcohol is Used as synthetic intermediate
Tetrahydrofurfuryl alcohol is Used in resins (prepolymers), sealants and adhesives

Tetrahydrofurfuryl alcohol is Used as laboratory reagent
Tetrahydrofurfuryl alcohol is Used in the formulation of agrochemicals

CHEMICAL AND PHYSICAL PROPERTIES OF TETRAHYDROFURFURYL ALCOHOL:
Chemical formula C5H10O2
Molar mass 102.133 g•mol−1
Appearance Colorless liquid
Density 1.0511 g/cm3
Boiling point 178 °C (352 °F; 451 K)
Flash point 83.9 °C (183.0 °F; 357.0 K)
CAS number 97-99-4
EC index number 603-061-00-7
EC number 202-625-6
Hill Formula C₅H₁₀O₂
Molar Mass 102.13 g/mol
HS Code 2932 13 00
Boiling point 178 °C (1013 hPa)
Density 1.05 g/cm3 (20 °C)
Explosion limit 1.5 - 9.7 %(V)
Flash point 73 °C
Ignition temperature 282 °C
Melting Point Vapor pressure 1 hPa (25 °C)
Assay (GC, area%) ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C) 1.052 - 1.054
Identity (IR) passes test
vapor density: 3.52 (vs air)
Quality Level: 100
vapor pressure: 2.3 mmHg ( 39 °C)
Assay:99%
Form: liquid
expl. lim.: 9.7 %
refractive index: n20/D 1.452 (lit.)
bp: 178 °C (lit.)
mp: −80 °C (lit.)
Solubility:
acetone: miscible(lit.)
alcohol: miscible(lit.)
benzene: miscible(lit.)
chloroform: miscible(lit.)
diethyl ether: miscible(lit.)
water: miscible(lit.)
Molecular Weight 102.13 g/mol
XLogP3-AA -0.1
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 1
Exact Mass 102.068079557 g/mol
Monoisotopic Mass 102.068079557 g/mol
Topological Polar Surface Area 29.5Ų
Heavy Atom Count 7
Formal Charge 0
Complexity 54
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 1.05000 to 1.05200 @ 25.00 °C.
Pounds per Gallon - (est).: 8.737 to 8.754
Refractive Index: 1.44900 to 1.45500 @ 20.00 °C.
Melting Point: -80.00 °C. @ 760.00 mm Hg
Boiling Point: 178.00 to 179.00 °C. @ 760.00 mm Hg
Acid Value: 3.00 max. KOH/g
Vapor Pressure: 0.326000 mmHg @ 25.00 °C. (est)
Vapor Density: 3.52 ( Air = 1 )
Flash Point: 183.00 °F. TCC ( 83.89 °C. )
logP (o/w): -0.367 (est)
Soluble in:
alcohol
ethyl ether
water, 4.634e+005 mg/L @ 25 °C (est)
water, 1.00E+06 mg/L @ 25 °C (exp)
Appearance: colourless to light-yellow liquid
Boiling point: 178°C
Flash point: 73°C (closed cup), 84°C (open cup)
Melting point/freezing point: < -120°C
pH: 5 - 6 (250 g/L in water)
Refractive index (20°C): 1.449 - 1.453
Relative density (20°C/4°C): 1.052
Relative density (20°C/20°C): 1.054 - 1.056
Viscosity (20°C): 6.4 mPa.s
Vapour pressure (25°C): 0.142 kPa
Evaporation rate (butyl acetate = 1): 0.03
Auto-ignition temperature: 282°C
Heat of vaporization: 120.6 cal/g
Solubility in water: miscible
Soluble in: ethanol, ether, chloroform, methanol, 1-propanol,
iso-amyl alcohol, ethyl acetate
Partition coefficient n-octanol/water: -0.14
Hansen solubility parameter:
• Non-polar: 9.8
• Polar: 5.0
• Hydrogen bonding: 7.8
Dielectric constant (23°C): 13.6
Shelf life:
The product should be stored under ambient conditions (max. 25°C), protected from exposure to direct sunlight, heat sources and air.
Storage under nitrogen atmosphere is recommended


SYNONYMS OF TETRAHYDROFURFURYL ALCOHOL:
tetrahydrofurfuryl alcohol
tetrahydrofurfuryl alcohol, (R)-isomer
tetrahydrofurfuryl alcohol, (S)-isomer
TETRAHYDROFURFURYL ALCOHOL
97-99-4
(Tetrahydrofuran-2-yl)methanol
Tetrahydro-2-furanmethanol
oxolan-2-ylmethanol
THFA
2-Furanmethanol, tetrahydro-
Tetrahydro-2-furanylmethanol
QO Thfa
Furfuryl alcohol, tetrahydro-
Tetrahydro-2-furancarbinol
Tetrahydrofuryl carbinol
Tetrahydro-2-furfuryl alcohol
Tetrahydro-2-furylmethanol
Tetrahydrofurylalkohol
2-(Hydroxymethyl)tetrahydrofuran
tetrahydrofuran-2-ylmethanol
Tetrahydrofurylmethanol
FEMA No. 3056
TETRAHYDROFURFURYLALCOHOL
Tetrahydrofurfurylalkohol
tetrahydro furfuryl alcohol
Oxolan-2-methanol
NSC 15434
2-Hydroxymethyl-Tetrahydrofuran
DTXSID1029128
MFCD00005372
.alpha.-Tetrahydrofurfuryl alcohol
XD95821VF9
NSC-15434
DTXCID909128
CAS-97-99-4
Tetrahydrofurylalkohol [Czech]
CCRIS 2923
HSDB 5314
Tetrahydrofurfurylalkohol [Czech]
EINECS 202-625-6
Furanmethanol, tetrahydro-
BRN 0102723
(R)-(-)-Tetrahydrofurfurylalcohol
UNII-XD95821VF9
AI3-00104
MFCD03093085
MFCD04972320
[(2R)-tetrahydrofuran-2-yl]methanol
Thfa (van)
tetrahydrofuranmethanol
tetrahydrofuran-methanol
(oxolan-2-yl)methanol
tetrahydrofuran--methanol
tetrahydrofuran - methanol
tetrahydrofuran-2-methanol
EC 202-625-6
WLN: T5OTJ B1Q
2-tetrahydrofuranyl-methanol
SCHEMBL4208
Qo tetrahydrofurfuryl alcohol
(tetrahydro-2furanyl)methanol
2-hydroxymethyltetrahydrofuran
tetrahydro-furan-2-ylmethanol
2-hydroxymethyl tetrahydrofuran
alpha-Tetrahydrofurfuryl alcohol
(R)-Tetrahydro-2-furanmethanol
Tetrahydrofurfuryl alcohol, 8CI
CHEMBL2287521
rac-tetrahydrofuran-2-ylmethanol
THFA,Tetrahydro-2-furancarbinol
(RS)-tetrahydrofuran-2-methanol
FEMA 3056
Tetrahydrofurfuryl alcohol, 98%
Tetrahydrofurfuryl alcohol, 99%
(tetrahydro-furan-2-yl)-methanol
CHEBI:137944
rac-2-hydroxymethyl-tetrahydrofuran
NSC15434
Tetrahydrofurfuryl alcohol, >=98%
Tox21_201324
Tox21_303393
STL280495
AKOS000118902
AKOS016352940
AM81815
CS-W004058
SB44757
SB44818
TETRAHYDROFURFURYL ALCOHOL [MI]
TETRAHYDROFURFURYL ALCOHOL [FCC]
NCGC00249026-01
NCGC00257256-01
NCGC00258876-01
TETRAHYDROFURFURYL ALCOHOL [FHFI]
TETRAHYDROFURFURYL ALCOHOL [HSDB]
TETRAHYDROFURFURYL ALCOHOL [INCI]
93842-55-8
SY106537
SY227666
DB-016193
FT-0605078
FT-0650427
FT-0695328
FT-0771179
T0106
TETRAHYDROFURFURYL ALCOHOL, (+/-)-
EN300-19349
Tetrahydrofurfuryl alcohol, analytical standard
D77646
A845782
J-524856
Q2406741
F0001-0790
(Tetrahydrofuran-2-yl)methanol
102723 [Beilstein]
202-625-6 [EINECS]
2-Furanmethanol, tetrahydro- [ACD/Index Name]
97-99-4 [RN]
LU2450000
Oxolan-2-yl methanol
oxolan-2-ylmethanol
T5OTJ B1Q [WLN]
Tetrahydro-2-furanmethanol
Tetrahydro-2-furanylmethanol [ACD/IUPAC Name]
Tetrahydro-2-furanylmethanol [German] [ACD/IUPAC Name]
Tétrahydro-2-furanylméthanol [French] [ACD/IUPAC Name]
Tetrahydrofuran-2-ylmethanol
Tetrahydrofurfuryl alcohol
THFA
UNII:XD95821VF9
XD95821VF9
(??)-Tetrahydro-2-furanmethanol
(±)-2-(Hydroxymethyl)tetrahydrofuran
(±)-tetrahydrofurfuryl alcohol
(oxolan-2-yl)methanol
(R)-(-)-TETRAHYDROFURFURYLALCOHOL
(R)-(tetrahydrofuran-2-yl)methanol
(S)-(tetrahydrofuran-2-yl)methanol
(tetrahydro-furan-2-yl)-methanol
[(2R)-2-oxolanyl]methanol
[97-99-4] [RN]
1,4-Bis(5-phenyl-2-oxazolyl)benzene
2-(Hydroxymethyl)tetrahydrofuran
2-Furanmethanol, tetrahydro-, (2R)- [ACD/Index Name]
2-Hydroxymethyltetrahydrofuran
2-Hydroxymethyl-tetrahydrofuran
FEMA 3056
Furfuryl alcohol, tetrahydro-
Furfuryl alcohol, tetrahydro- (8CI)
MFCD03093085 [MDL number]
MFCD04972320 [MDL number]
OCc1ccco1
Oxolan-2-methanol
oxolan-2-ylmethan-1-ol
POPOP [Wiki]
Qo tetrahydrofurfuryl alcohol
QO Thfa
tetrahydro furfuryl alcohol
Tetrahydro-2-furancarbinol
Tetrahydro-2-furfuryl alcohol
Tetrahydro-2-furylmethanol
Tetrahydrofurancarbinol, 2-Hydroxymethyltetrahydrofuran
tetrahydro-furfuryl acrylate
Tetrahydrofurfuryl alcohol, 8CI
tetrahydrofurfurylalcohol
Tetrahydrofurfurylalkohol [Czech]
Tetrahydrofurfurylalkohol
Tetrahydrofuryl carbinol
Tetrahydrofurylalkohol
Tetrahydrofurylmethanol
Thfa (van)
THFA,Tetrahydro-2-furancarbinol
α-tetrahydrofurfuryl alcohol
α-Tetrahydrofurfuryl alcohol
ξ-Tetrahydro-2-furanmethanol

1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]propan-2-ol; 2-propanol, 1,1',1',1'''-(1,2-ethanediyldinitrilo)tetrakis- cas no: 102-60-3

SYNONYMS THPS; Pyroset TKO; Retardol S; Octakis(hydroxymethyl)diphosphonium sulfate; Tetrakis(hydroxymethyl)phosphonium sulfate (2:1); Bis(tetrakis(hydroxymethyl)phosphonium)sulfate CAS NO. 55566-30-8; 58591-11-0; 65257-04-7

Tetrahydroxypropyl Ethylenediamine is a substituted amine.
Tetrahydroxypropyl Ethylenediamine is excellent antistatic, dispersing, anticorrosive, lubricating, cleansing, emulsifying, solubilizing abilities.


CAS Number: 102-60-3
EC Number: 203-041-4
Chem/IUPAC Name: 1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol
MOLECULAR FORMULA : C14H32N2O4


Tetrahydroxypropyl Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.
Tetrahydroxypropyl Ethylenediamine is biodegradable.


Tetrahydroxypropyl Ethylenediamine is easily soluble in water, and the aqueous solution is weakly alkaline.
Tetrahydroxypropyl Ethylenediamine is excellent antistatic, dispersing, anticorrosive, lubricating, cleansing, emulsifying, solubilizing abilities.
Tetrahydroxypropyl Ethylenediamine is a chelating agent that binds with metal ions or metallic compounds, preventing them from adhering to a surface (such as skin, hair, or clothing) or causing contamination, such as in the case of trace amounts of iron.


Tetrahydroxypropyl Ethylenediamine is colorless viscous liquid.
Tetrahydroxypropyl Ethylenediamine is gentle, non-irritating and non-greasy pH adjuster.
Tetrahydroxypropyl Ethylenediamine is formulated with the feature high alcohol compatibility to stimulate a pleasant, nonsticky sensation on the skin.


Tetrahydroxypropyl Ethylenediamine is miscible with water, methanol, ethanol, toluene, ethylene glycol and perchloroethylene.
Tetrahydroxypropyl Ethylenediamine is incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents and chloroformates.
Tetrahydroxypropyl Ethylenediamine is an ideal neutralizing agent for gel formulations such as carbomer.


Tetrahydroxypropyl Ethylenediamine forms very few nitrosamines when compared to other amine-containing bases.
Tetrahydroxypropyl Ethylenediamine is colorless liquid.
Tetrahydroxypropyl Ethylenediamine is colorless viscous liquid.


Tetrahydroxypropyl Ethylenediamine exhibits high alcohol compatibility and gives the skin a non-sticky and comfortable feel.
Tetrahydroxypropyl Ethylenediamine forms very few nitrosamines when compared to other amine-containing bases.
Tetrahydroxypropyl Ethylenediamine is a reaction product of ethylenediamine with 4 moles of propylene oxide.


Tetrahydroxypropyl Ethylenediamine is formulated with the feature high alcohol compatibility to stimulate a pleasant, nonsticky sensation on the skin.
Tetrahydroxypropyl Ethylenediamine is a reaction product of ethylenediamine with 4 moles of propylene oxide.
This gel, Tetrahydroxypropyl Ethylenediamine, is formulated with the feature high alcohol compatibility to stimulate a pleasant, nonsticky sensation on the skin.


At room temperature, Tetrahydroxypropyl Ethylenediamine is clear soluble in water, alcohol, and propylene glycol.
Tetrahydroxypropyl Ethylenediamine forms dull dispersions in mineral oils.
It has been demonstrated that the tendency of Tetrahydroxypropyl Ethylenediamine to form nitrosamines is extremely slight if it is substituted for other bases that contain amines.


Tetrahydroxypropyl Ethylenediamine is a derivative of Ethylenediamine here all hydrogens connected with nitrogens are replaced with four 2-hydroxypropyl groups.
Tetrahydroxypropyl Ethylenediamine is particularly suited as a neutralizing agent for polymers in clear gel formulations and forms clear solutions with solvents like water, ethanol, isopropanol, and propylene glycol.


The gels formulated with Tetrahydroxypropyl Ethylenediamine have excellent alcohol compatibility and have a pleasant non-tacky skin feeling.
In comparison to other bases containing amines, it could be proved that Tetrahydroxypropyl Ethylenediamine shows a considerably lower tendency to form nitroamines.


Tetrahydroxypropyl Ethylenediamine has been toxicologically tested with regard to cosmetic use.
Within the recommended applications and concentrations of Tetrahydroxypropyl Ethylenediamine, no indications of toxicological risks were found.
Tetrahydroxypropyl Ethylenediamine is gentle, non-irritating and non-greasy pH adjuster.



USES and APPLICATIONS of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
Tetrahydroxypropyl Ethylenediamine is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Tetrahydroxypropyl Ethylenediamine is used in the following products: coating products, adhesives and sealants, washing & cleaning products and cosmetics and personal care products.


Other release to the environment of Tetrahydroxypropyl Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Tetrahydroxypropyl Ethylenediamine is used in the following areas: agriculture, forestry and fishing.


Release to the environment of Tetrahydroxypropyl Ethylenediamine can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Tetrahydroxypropyl Ethylenediamine is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Tetrahydroxypropyl Ethylenediamine can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Tetrahydroxypropyl Ethylenediamine is used in the following products: coating products, adhesives and sealants and polymers.


Tetrahydroxypropyl Ethylenediamine can be found in products with material based on: plastic used for toys and other articles intended for children’s use, including baby-bottles, plastic used for articles with intense direct dermal (skin) contact during normal use (e.g. handles, ball pens), plastic (e.g. food packaging and storage, toys, mobile phones) and wood (e.g. floors, furniture, toys).


Tetrahydroxypropyl Ethylenediamine is used for the manufacture of: chemicals and plastic products.
Other release to the environment of Tetrahydroxypropyl Ethylenediamine is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Tetrahydroxypropyl Ethylenediamine is used in the following products: coating products, adhesives and sealants, adsorbents, air care products, anti-freeze products, metals, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay and non-metal-surface treatment products.
Release to the environment of Tetrahydroxypropyl Ethylenediamine can occur from industrial use: formulation of mixtures, formulation in materials, for thermoplastic manufacture and in the production of articles.


Tetrahydroxypropyl Ethylenediamine is used in the following products: polymers and adhesives and sealants.
Tetrahydroxypropyl Ethylenediamine is used in the following areas: formulation of mixtures and/or re-packaging.
Tetrahydroxypropyl Ethylenediamine is used for the manufacture of: chemicals.


Release to the environment of Tetrahydroxypropyl Ethylenediamine can occur from industrial use: for thermoplastic manufacture, in the production of articles, formulation of mixtures, formulation in materials and in processing aids at industrial sites.
Release to the environment of Tetrahydroxypropyl Ethylenediamine can occur from industrial use: manufacturing of the substance, formulation of mixtures, and thermoplastic manufacture.


Tetrahydroxypropyl Ethylenediamine is used metal complexing agent for electroless copper plating in circuit board manufacturing.
Tetrahydroxypropyl Ethylenediamine is used crosslinking agent for polyurethane products.
Tetrahydroxypropyl Ethylenediamine is used concrete water reducing agent raw materials.


Tetrahydroxypropyl Ethylenediamine is used for a flux and cleaning agent.
Tetrahydroxypropyl Ethylenediamine is used for synthetic rubber, antistatic agent, synthetic plastic stabilizer.
Tetrahydroxypropyl Ethylenediamine is used as metal complexing agent, as scaling powder and cleaner in electroless copper PCB plating.


Tetrahydroxypropyl Ethylenediamine is used Chelating agent, solvent.
Tetrahydroxypropyl Ethylenediamine is used as metal complexing agent, used as scaling powder and cleaner in electroless copper PCB plating.
Tetrahydroxypropyl Ethylenediamine is a chelant and it is used in cosmetics to bind metal ions to prevent unwanted metal-reactions within the formulation which could have negative effects on stability, preservation and product performance.


In Colorants Tetrahydroxypropyl Ethylenediamine helps to preserve the intended color result and product stability in case of metal ion exposure during manufacturing of the tint.
Tetrahydroxypropyl Ethylenediamine is mainly used for electroless copper plating complexing agent.


Tetrahydroxypropyl Ethylenediamine is used for electroless copper plating in circuit board manufacturing.
Tetrahydroxypropyl Ethylenediamine is mainly used for chemical copper plating complexing agent.
Metal complexing agent, Tetrahydroxypropyl Ethylenediamine is used for electroless copper plating, flux and cleaning agent in circuit board manufacturing.


Tetrahydroxypropyl Ethylenediamine is used as solvent.
Tetrahydroxypropyl Ethylenediamine is used as cleansing agent.
Tetrahydroxypropyl Ethylenediamine is used as emulsifying agent, dispersing agent.


Tetrahydroxypropyl Ethylenediamine is used as corrosion inhibitor, lubricant.
Tetrahydroxypropyl Ethylenediamine is used as antistatic agent.
Tetrahydroxypropyl Ethylenediamine is used as chelating agent.


Tetrahydroxypropyl Ethylenediamine is used as intermediate in organic synthesis.
Tetrahydroxypropyl Ethylenediamine is used Chelating agent in personal care products
Tetrahydroxypropyl Ethylenediamine is a complexing agent.
Cosmetic Uses of Tetrahydroxypropyl Ethylenediamine: chelating agents


Tetrahydroxypropyl Ethylenediamine uses and applications include: Detergent polymer; for surface coatings; emulsions; paints; paper and leather finishes; water treatment; dispersant and scale inhibitor for oil field water treatment; binder for textiles; thickener for fabric laminates, textile printing pastes; antistat, binder, film-former in cosmetics; thickener, stabilizer for cosmetics, paints, inks, waxes, polishes, detergents, etc.; in food packaging adhesives; in paperpaperboard in contact with dry food.


Tetrahydroxypropyl Ethylenediamine is a Polymers of two or more monomers consisting of acrylic acid, methacrylic acid, or their simple esters.
Tetrahydroxypropyl Ethylenediamine is used Cosmetic, Water Treatment, Textiles, Adhesives, Detergent.
Tetrahydroxypropyl Ethylenediamine is used as a catalyst in the production of urethane foams.


Tetrahydroxypropyl Ethylenediamine acts as a complexing agent, plasticizer, surfactant solubilizer and curing agent for epoxy resin.
Tetrahydroxypropyl Ethylenediamine is also used as a viscosity modifier and as an anti-bloating agent for cattle.
Tetrahydroxypropyl Ethylenediamine is utilized in piezoelectric crystal detectors of sulfur dioxide and in additives for paint.


Tetrahydroxypropyl Ethylenediamine serves as a biological buffer as well as reagent for manganese.
Further, Tetrahydroxypropyl Ethylenediamine finds application in adhesives and sealant chemicals.
In addition to this, Tetrahydroxypropyl Ethylenediamine is used as a cross-linking agent.


Tetrahydroxypropyl Ethylenediamine is used as a catalyst in manufacturing urethane foams, epoxy resin curing agent, complexing agent, humectant, plasticizer, chelate, surfactant solubilizer, viscosity modifier, and intermediate.
Tetrahydroxypropyl Ethylenediamine is also used as an anti-bloating agent for cattle.


Tetrahydroxypropyl Ethylenediamine is used in piezoelectric crystal detectors
Tetrahydroxypropyl Ethylenediamine is the most suitable neutralizing agent for gel formulations using carbomer, etc.
Tetrahydroxypropyl Ethylenediamine is used for Face care, Body care, Make-up, Face and body hygiene, Hair care.


Tetrahydroxypropyl Ethylenediamine is also used by the cosmetic industry in soap-making and in stearate creams.
Tetrahydroxypropyl Ethylenediamine is used Antiperspirant/Deodorants, Body Care, Oral Care, Sun Care, and more.
These high-performing products enable the development of formulations that fulfill consumer’s needs.


Gels formulated with Tetrahydroxypropyl Ethylenediamine feature high alcohol compatibility and stimulate a pleasant, non-sticky sensation on the skin.
Other applications for Tetrahydroxypropyl Ethylenediamine in the cosmetic field are the manufacture of soap, the production of stearate cremes, and the neutralization of sunscreens that contain acid groups.


Tetrahydroxypropyl Ethylenediamine is a neutralizing agent for carbomer resins.
Tetrahydroxypropyl Ethylenediamine is used in the production of gels.
Tetrahydroxypropyl Ethylenediamine finds application in formulating skin-, sun-, men-, mother- & baby-, body-, face and color care products.


Tetrahydroxypropyl Ethylenediamine is also used in skin cleansing, hair care (hair coloring, shampoos, conditioners, styling products), self-tanning, liquid soaps and shower/bath products.
Tetrahydroxypropyl Ethylenediamine is used neutralizing agent for carbomer resins, e.g. in the production of gels.


Tetrahydroxypropyl Ethylenediamine is an eminently suitable neutralizing agent for carbomer resin.
For example: in the production of gels.
Tetrahydroxypropyl Ethylenediamine is used Bath & Shower, Body Care, Eye Liner, Face Care, Foundations, Mascara, Skin Care, Skin Cleansing, Sun Care.


Tetrahydroxypropyl Ethylenediamine is a neutralizing agent that is used for carbomer resins (e.g., in the production of gels).
Tetrahydroxypropyl Ethylenediamine is a clear, viscous liquid that is commonly used in baby care and cleansing, body care, face cleansing, hair coloring, shower/bath products, styling, etc.


Tetrahydroxypropyl Ethylenediamine is used for the manufacture of soap and stearate cremes.
Tetrahydroxypropyl Ethylenediamine is used Skin Care, Cleanser, Sun Care, Mother and baby, Hair care, Shampoo and Conditioner, Styling product, Hair color, Bath and Body
Men, Skin care, Body care, Face Care, Self Tanning, Pet Care, Pet Care TSCA, and Pet Care DSL.



WHAT DOES TETRAHYDROXYPROPYL ETHYLENEDIAMINE DO IN A FORMULATION?
*Chelating



FUNCTIONS OF TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
*Chelating agent:
Tetrahydroxypropyl Ethylenediamine reacts and forms complexes with metal ions which could affect the stability and/or appearance of cosmetic products


BENEFITS CLAIMS OF TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
*Chelating
*Sun Protection
*Cleansing
*Self-Tanning
*Non-Irradiated
*Ease of Styling
*After-Sun Repair



FUNCTIONS OF TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
*Scale Inhibitor
*Acid
*Dispersant
*Stabilizer
*pH adjuster / buffer
*Neutralizing Agent



ALTERNATIVE PARENTS OF TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
*Trialkylamines
*Secondary alcohols
*Organopnictogen compounds
*Hydrocarbon derivatives



SUBSTITUENTS OF TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
*Tertiary aliphatic amine
*Tertiary amine
*Secondary alcohol
*1,2-aminoalcohol
*Organic oxygen compound
*Organopnictogen compound
*Hydrocarbon derivative
*Organooxygen compound
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in: water, 1e+006 mg/L @ 25 °C (est)
Formula: C14h32n2o4
CAS No.: 102-60-3
EINECS: 203-041-4
Status: Liquid Catalyst
Response Type: Polymerization
Classification: Homogeneous Catalysts
Effect Size: Tetrahydroxypropyl Ethylenediamine
Application: Industry
Appearance: Colorless to light yellow clear liquid
Assay: 99%min.
Appearance: Colorless to light yellow clear liquid
Assay: 99%min
Content of water: ≤0.15
pH value: 8.0-11.0
Solubility: Clear liquid
Melting point: 32°C
Boiling point: 175-181 °C0.8 mm Hg(lit.)
Density: 1.03 g/mL at 20 °C(lit.)
Vapor pressure: 1 mm Hg ( 20 °C)
Refractive index: n20/D 1.4812(lit.)
Fp: >230 °F
Storage temp.: Store below 30°C.
PKA: 14.23±0.20(Predicted)
Specific Gravity: 1.013
PH: 10.4 (10g/l, H2O, 20℃)
Appearance: Colorless to light yellow viscous liquid
Colorless viscous liquid
PH Value, 1% water solution: 10.0 ~12.0
Effective content (%): 73.0 ~ 77.0
Color (Pt-Co): ≤ 30
Dynamic viscocity: (mPa’s, 25℃） 205 ~ 360
Proportion (g/cm3, 25℃）: 1.040 ~ 1.060
Solubility: 100% soluble in water

Physical state: viscous
Color: colorless
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: 175 - 181 °C at 1 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 211 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility soluble
Partition coefficient: n-octanol/water
log Pow: -2,08 at 25 °C
Vapor pressure: 0,000011 hPa at 20 °C
Density: 1,013 g/mL at 25 °C

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 63,94 mN/m at 20 °C
Water Solubility: 79.4 g/L
logP: -0.66, logP: -0.89, logS: -0.57
pKa (Strongest Acidic): 14.69
pKa (Strongest Basic): 9.5
Physiological Charge: 1
Hydrogen Acceptor Count: 6
Hydrogen Donor Count: 4
Polar Surface Area: 87.4 Ų
Rotatable Bond Count: 11
Refractivity: 80.85 m³•mol⁻¹

Polarizability: 33.93 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule
Density: 1.03
Boiling Point: 240°C (10mmHg)
Flash Point: >110°C (230°F)
Odor: Odorless
Refractive Index: 1.48
Merck Index: 14,3599
Solubility Information: Miscible with water,methanol,ethanol,toluene,ethylene glycol and perchloroethylene.
Formula Weight: 292.42
Percent Purity: 99%
Chemical Name or Material: N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
Molecular Weight: 292.41 g/mol

XLogP3-AA: -0.7
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 11
Exact Mass: 292.23620751 g/mol
Monoisotopic Mass: 292.23620751 g/mol
Topological Polar Surface Area: 87.4Ų
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 4
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of TETRAHYDROXYPROPYL ETHYLENEDIAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Edetol [USAN:INN]; 1,1,1,1-(Ethylenedinitrilo)tetra-2-propanol
Entprol
Tetrakis(2-hydroxypropyl)ethylenediamine
2-Propanol, 1,1,1,1-(1,2-ethanediyldinitrilo)tetrakis-
2-Propanol, 1,1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
THPE
Chemical Q75
EDTP Tetrahydroxypropyl ethylenediamine
Edetol, Entprol, (Ethylenedinitrilo)tetra-2-propanol, Quadrol
102-60-3
203-041-4
1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS(2-PROPANOL)
2-PROPANOL, 1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS-
EDETOL [HSDB]
EDETOL [INN]
EDETOL [USAN]
ENTPROL [MI]
N,N,N',N'-TETRAKIS (2-HYDROXYPROPYL) ETHYLENEDIAMINE
N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE
TETRAHYDROXYPROPYL ETHYLENEDIAMINE
NSC-369219
QUADROL
TETRAHYDROXYPROPYL ETHYLENEDIAMINE
TETRAHYDROXYPROPYL ETHYLENEDIAMINE [INCI]
Quadrol
Edetol
Entprol
Tetrahydroxypropyl Ethylenediamine
Quadrol
THPE
(Ethylenedinitrilo)tetra-2-propanol
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
1-({2-[Bis(2-hydroxypropyl)amino]ethyl}(2-hydroxypropyl)amino)propan-2-ol
1-{2-[Bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino}-2-propanol
1-{2-[Bis(2-oxidanylpropyl)amino]ethyl-(2-oxidanylpropyl)amino}propan-2-ol
Tetrahydroxypropyl ethylenediamine
Tetrahydroxypropyl ethylenediamine
Tetrakis(2-hydroxypropyl)ethylenediamine
1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol
1,1',1'',1'''-(Ethylenedinitrilo)tetrakis(2-propanol)
1,1',1',1'''-(Ethylenedinitrilo)tetra-2-propanol
2-Propanol, 1,1',1'',1'''-(ethylenedinitrilo)tetra-
2-Propanol, 1,1',1',1'''-(1,2-ethanediyldinitrilo)tetrakis-
Adeka Quadrol
ENTPROL
Entprol
N,N,N',N'-Tetra(2-hydroxypropyl)ethylenediamine
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
Tetrahydroxypropyl Ethylenediamine
Quadrol
Quadrol L
THPE
1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol monotosylate
Quadrol
N,N,N',n'-tetrakis(2-hydroxypropyl)ethylenediamine
Tetrahydroxypropyl ethylenediamine
1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol
2-Propanol,1,1',1'',1'''-(ethylenedinitrilo)tetra- (6CI,7CI,8CI)
1,1',1'',1'''-(1,2-Ethanediyldinitrilo)tetrakis[2-propanol]
1,1',1'',1'''-(Ethylenedinitrilo)tetra(2-propanol)
1,1',1'',1'''-(Ethylenedinitrilo)tetrakis(2-propanol)
Adeka Quadrol
ENTPROL
EPD 300
Edetol
Laprol 294
N,N,N',N'-Tetra(2-hydroxypropyl)ethylenediamine
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
N,N,N',N'-Tetrakis(b-hydroxypropyl)ethylenediamine
NP 300
NSC 369219
Neutrol
Tetrahydroxypropyl Ethylenediamine
Newpol NP 300
Quadrol
Quadrol L
THPE
Tetrakis(2-hydroxypropyl)ethylenediamine
1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS(2-PROPANOL)
2-PROPANOL, 1,1',1'',1'''-(1,2- ETHANEDIYLDINITRILO)TETRAKIS-
EDETOL
EDETOL [HSDB]
EDETOL [INN]
EDETOL [USAN]
ENTPROL [MI]
N,N,N',N'-TETRAKIS (2-HYDROXYPROPYL) ETHYLENEDIAMINE
N,N,N',N'-TETRAKIS( 2-HYDROXYPROPYL)ETHYLENEDIAMINE
TETRAHYDROXYPROPYL ETHYLENEDIAMINE
NSC-369219
QUADROL
TETRAHYDROXYPROPYL ETHYLENEDIAMINE
TETRAHYDROXYPROPYL ETHYLENEDIAMINE [INCI]
102-60-3
Edetol
Quadrol
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
Entprol
Tetrahydroxypropyl Ethylenediamine
Adeka Quadrol
Quadrol L
1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol
Tetrahydroxypropyl ethylenediamine
2-Propanol, 1,1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-
Edetolum [Latin]
1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))tetrakis(propan-2-ol)
Edetol [USAN:INN]
Edetolum
NSC 369219
EDTP
N,N,N',N'-Tetra(2-hydroxypropyl)ethylenediamine
1,1',1'',1'''-Ethylenedinitrilotetrapropan-2-ol
HSDB 5349
1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]propan-2-ol
1,1',1'',1'''-(Ethylenedinitrilo)tetrakis(2-propanol)
TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE
EINECS 203-041-4
NSC-369219
BRN 1781143
UNII-Q4R969U9FR
2-Propanol, 1,1',1'',1'''-(ethylenedinitrilo)tetra-
CCRIS 8275
Q4R969U9FR
DTXSID9026689
Ethylenediamine-N,N,N',N'-tetra-2-propanol
2-Propanol, 1',1',1'',1'''-(1,2-ethanediyldinitrilo)tetrakis-
C14H32N2O4
Edetol (USAN)
1,1',1'',1'''-(Ethanediylnitrilo)tetrakis(2-propanol)
NCGC00164339-02
EDETOL [USAN]
EC 203-041-4
4-04-00-01685 (Beilstein Handbook Reference)
1,1',1',1'''-(Ethylenedinitrilo)tetra-2-propanol
DTXCID806689
Ethylenedinitrilotetra-2-Propanol
N,N,N',N'-Tetrakis(2-Hydroxypropyl)ethylenediamine, 98%
2-Propanol, 1,1',1',1'''-(1,2-ethanediyldinitrilo)tetrakis-
CAS-102-60-3
N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
EDTP
1,1',1'',1'''-(ethane-1,2-diyldinitrilo)tetrapropan-2-ol
Quadrol(R)
(Ethylenedinitrilo)tetra-2-propanol
Tetrahydroxypropyl Ethylenediamine (TN)
EDETOL [HSDB]
EDETOL [INN]
ENTPROL [MI]
SCHEMBL48412
MLS004773924
N,N,N,N-Tetrakis(2-Hydroxypropyl)- Ethylenediamine
CHEMBL1573178
CHEBI:193592
HMS3264C08
Pharmakon1600-01301023
HY-B2149
Tox21_112102
Tox21_201973
Tox21_300552
MFCD00004534
NSC369219
NSC760394
tetra(2-hydroxypropyl)ethylenediamine
1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))-tetrakis(propan-2-ol)
AKOS015892820
C14-H32-N2-O4
Tox21_112102_1
CCG-230630
NSC-760394
SB82446
Tetra (2-hydroxypropyl) ethylenediamine
NCGC00164339-01
NCGC00164339-03
NCGC00164339-04
NCGC00164339-05
NCGC00254289-01
NCGC00259522-01
BS-23689
SMR001600027
LS-122312
CS-0020301
FT-0626306
T0781
D03948
F71260
N(CCN(CC(C)O)CC(C)O)(CC(C)O)CC(C)O
NNN'N'-Tetrakis(2-Hydroxypropyl)ethylenediamine
TETRAHYDROXYPROPYL ETHYLENEDIAMINE [INCI]
Tetrakis-[N-(2-hydroxy-propyl)]-ethylenediamine
1,1',1'',1'''-ethylendinitrilotetrapropan-2-ol
A800588
J-000740
n,n,n',n'-tetrakis (2-hydroxypropyl) ethylenediamine
N,N,N',N'-tetrakis-(2-hydroxypropyl)ethylenediamine
N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine;EDTP
Q26841009
Ethylenedinitrilo)tetra-2-propanol, 1,1',1'',1'''-(
1, 1', 1'', 1'''- ethylenedinitrilotetrapropan- 2- ol
2-Propanol, 1,1',1',1'-(1,2-ethanediyldinitrilo)tetrakis-
1,1',1'',1'''-(ethane-1,2-diylbis(azanetriyl))tetrapropan-2-ol
1,1',1'',1'''-(1,2-ETHANEDIYLDINITRILO)TETRAKIS(2-PROPANOL)
1-[2-[bis(2-hydroxypropyl)amino]ethyl-(2-hydroxypropyl)amino]-2-propanol
1-[2-[bis(2-oxidanylpropyl)amino]ethyl-(2-oxidanylpropyl)amino]propan-2-ol
2-propanol, 1,1', 1'', 1'''-(1,2-etanodiildinitrilo) tetraquis-
1,1'',1'''',1''''''-(Ethane-1,2-diylbis(azanetriyl))tetrakis(propan-2-ol)
N,N,N inverted exclamation marka,N inverted exclamation marka-Tetrakis(2-hydroxypropyl)ethylenediamine

Tetraisopropyl orthotitanate belongs to the product group of organic titanates, which are known to be highly reactive organics that can be used in a broad range of processes and applications.
Tetraisopropyl orthotitanate is a colorless, slighty yellowish liquid that is very sensitive to moisture.
Tetraisopropyl orthotitanate, is a chemical compound with the formula Ti{OCH(CH3)2}4.

CAS Number: 546-68-9
Molecular Formula: C12H28O4Ti
Molecular Weight: 284.22
EINECS Number: 208-909-6

Titanium tetraisopropanolate, 546-68-9, Titanium isopropoxide, Titanium isopropylate, Titanium tetraisopropylate, Tetraisopropyl orthotitanate, Tilcom TIPT, Titanium tetraisopropoxide, Ti Isopropylate, Tetraisopropoxytitanium(IV), Isopropyl orthotitanate, Tetraisopropoxytitanium, Tetraisopropanolatotitanium, TETRAISOPROPYL TITANATE, propan-2-olate;titanium(4+), A 1 (titanate), Orgatix TA 10, Tetrakis(isopropoxy)titanium, Tyzor TPT, Isopropyl Titanate, TTIP, Tetraisopropoxide titanium, Titanium tetra-n-propoxide, Titanium(4+) isopropoxide, Titanic acid isopropyl ester, Titanium, tetrakis(1-methylethoxy)-, Isopropyl alcohol, titanium(4+) salt, Titanium tetrakis(isopropoxide), Isopropyl titanate(IV) ((C3H7O)4Ti), 2-Propanol, titanium(4+) salt, titanium(IV) propan-2-olate, 2-Propanol, titanium(4+) salt (4:1), Titanium(IV) Tetraisopropoxide, Isopropyl alcohol titanium(4+) salt, 76NX7K235Y, titanium(4+) tetrakis(propan-2-olate), Isopropyl titanate(IV), titanium tetra(isopropoxide), Titanium isopropylate (VAN), TITANIUM (IV) ISOPROPOXIDE, titanium(4+) tetrapropan-2-olate, HSDB 848, Tetraksi(isopropanolato)titanium, NSC-60576, Isopropyl alcohol, titanium salt, Titanic acid tetraisopropyl ester, Titanium isopropoxide (Ti(OC3H7)4), EINECS 208-909-6, Titanium isopropoxide (Ti(OCH7)4), NSC 60576, Titanic(IV) acid, tetraisopropyl ester, titanium(IV)tetraisopropoxide, C12H28O4Ti, UNII-76NX7K235Y, TIPT, Ti(OiPr)4, tetraisopropoxy titanium, tetraisopropoxy-titanium, titaniumtetraisopropoxide, titaniumtetraisopropylate, titanium(IV)isopropoxide, tetra-isopropoxy titanium, titanium (IV)isopropoxide, tetra-iso-propoxy titanium, titanium tetra-isopropoxide, titanium-tetra-isopropoxide, EC 208-909-6, titanium (4+) isopropoxide, Titanium isopropoxide(TTIP), VERTEC XL 110, tetraisopropoxytitanium (IV), titanium tetra (isopropoxide), titanium (IV)tetraisopropoxide, titanium (IV) tetraisopropoxide, TITANUM-(IV)-ISOPROPOXIDE, CHEBI:139496, AKOS015892702, TITANIUM TETRAISOPROPOXIDE [MI], TITANIUM TETRAISOPROPANOLATE [HSDB].

Tetraisopropyl orthotitanate, also known as titanium tetraisopropoxide, is a chemical compound with the molecular formula Ti(OCH(CH3)2)4.
Tetraisopropyl orthotitanate is a colorless to pale yellow liquid with a pungent odor.
Tetraisopropyl orthotitanate is commonly used as a catalyst and crosslinking agent in various industrial processes, including the production of polyesters, polyurethanes, and silicone elastomers.

Tetraisopropyl orthotitanate acts as a precursor for titanium dioxide (TiO2) nanoparticles and is utilized in the synthesis of organic-inorganic hybrid materials.
Additionally, Tetraisopropyl orthotitanate finds applications in adhesives, coatings, sealants, and as a surface treatment agent for glass and metal substrates.
Tetraisopropyl orthotitanate is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.

Tetraisopropyl orthotitanate appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol. About the same density as water. Vapors heavier than air.
Tetraisopropyl orthotitanate is an organic compound composed of titanium and isopropyl groups (-C(CH3)2).
Tetraisopropyl orthotitanate is used as a precursor for the production of titanium dioxide (TiO2), a white pigment widely used in paint, cosmetics, and food industries.

Tetraisopropyl orthotitanate is also used as a starting material in the synthesis of other titanium compounds and as a catalyst in organic synthesis.
Tetraisopropyl orthotitanate, also commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4.
This alkoxide of titanium(IV) is used in organic synthesis and materials science.

Tetraisopropyl orthotitanate is a diamagnetic tetrahedral molecule. Titanium isopropoxide is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.
The structures of the Tetraisopropyl orthotitanates are often complex. Crystalline titanium methoxide is tetrameric with the molecular formula Ti4(OCH3)16.
Alkoxides derived from bulkier alcohols such as isopropyl alcohol aggregate less.

Tetraisopropyl orthotitanate is mainly a monomer in nonpolar solvents.
Tetraisopropyl orthotitanate, the alkoxide of Ti(IV), is a widely used precursor of titanium oxide (TiO2) to form thin films, powders, nanomaterials and coatings.
Tetraisopropyl orthotitanate is also employed as a starting material to prepare porous titanosilicates and ion-exchange materials.

Tetraisopropyl orthotitanate is also a material of interest for electronic coating applications.
Tetraisopropyl orthotitanate reacts with water to deposit titanium dioxide.
Ti{OCH(CH3)2}4 + 2 H2O → TiO2 + 4 (CH3)2CHOH

This reaction is employed in the sol-gel synthesis of TiO2-based materials in the form of powders or thin films.
Typically water is added in excess to a solution of the alkoxide in an alcohol.
The composition, crystallinity and morphology of the inorganic product are determined by the presence of additives (e.g. acetic acid), the amount of water (hydrolysis ratio), and reaction conditions.

Tetraisopropyl orthotitanate is also used as a catalyst in the preparation of certain cyclopropanes in the Kulinkovich reaction.
Prochiral thioethers are oxidized enantioselectively using a catalyst derived from Ti(O-i-Pr)4.
Tetraisopropyl orthotitanate is a widely used item of commerce and has acquired many names in addition to those listed in the table.

The equilibrium reaction of Tetraisopropyl orthotitanate with dry isopropanol leads to tetraisopropyl titanate Ti(OCHMe 2 ) 4 with the evolution of hydrogen chloride .
To suppress the reverse reaction, the HCl gas is bound with ammonia and the resulting ammonium chloride (NH 4 Cl) is filtered off.
Above room temperature, pure tetraisopropyl orthotitanate is a clear, neutral (pH 7), colorless to slightly yellow liquid with the smell of isopropanol.

The technically pure substance contains a few percent by weight of isopropanol, which lowers the solidification point and thus makes handling the Tetraisopropyl orthotitanate easier.
In contrast to other titanic acid esters, Tetraisopropyl orthotitanate is present in monomeric form in non-polar solvents.
Tetraisopropyl orthotitanate is sensitive to moisture and hydrolyzes quickly in water in an exothermic reaction to form titanium dioxide and isopropanol.

Tetraisopropyl orthotitanate is suitable as a neutral compound for direct esterification of carboxylic acids with alcohols with elimination of water and is used on an industrial scale in the synthesis of esters that are used as plasticizers for polyvinyl chloride (PVC).
Tetraisopropyl orthotitanate reacts quickly in a transesterification reaction with free higher alcohols or glycols to form the corresponding orthotitanates - in the example with the isononanol trimethyl-3,5,5-hexanol to form tetra-isononyl titanate - and the isopropanol released is distilled off.

The Lewis acid formed transfers the isononanol residue to the carboxy group of the monoester to form 1,2-cyclohexanedicarboxylic acid diisononyl ester (DINCH) and reacts with free alcohol back to the Tetraisopropyl orthotitanate.
In contrast to acidic and basic esterification catalysts, significantly fewer colored by-products are formed under Tetraisopropyl orthotitanate, which is why larger excesses of alcohol (up to 25%) can be used to shift the equilibrium.
High conversion and product purity make the neutralization and washing steps usually required for esterifications unnecessary.

Tetraisopropyl orthotitanate concentrations of only 0.05 to 0.2%, based on the ester product, are usually required.
In transesterifications with Tetraisopropyl orthotitanate, the tetraalkyl orthotitanate initially formed, as in esterifications, catalyzes the exchange of the alkoxy group of the starting ester with that of the alcohol.
In the direct esterification of terephthalic acid with ethylene glycol and subsequent polycondensation, when using Tetraisopropyl orthotitanate, the amount of commonly used antimony trioxide can be reduced and even eliminated and PET can be obtained with mechanical and optical properties suitable for fibers, films and beverage bottles.

The so-called second generation Phillips catalysts for the polymerization of ethene and propene consist of magnesium - titanium compounds and triethyl aluminum as a co-catalyst.
The titanium component is often introduced via titanium isopropoxide.
The catalyst systems are significantly (10 to 100 times) more active than the first generation catalysts and can therefore remain in the product.

They enable the production of linear low-density Tetraisopropyl orthotitanate and high-density polyethylene (HDPE) with a narrow molecular weight distribution .
In the presence of tetraisopropyl titanate and (+)- or (−)-tartaric acid diethyl ester in dichloromethane at −70 to −20 °C, achiral primary allyl alcohols are enantioselectively epoxidized.
A classic example is the epoxidation of geraniol with tert -butyl hydroperoxide to give geraniol 2,3-oxide in very high chemical yield and high enantiomeric excess.

Tetraisopropyl orthotitanate is a versatile compound that can be used in various industries, including pigment production, organic synthesis, and polymer synthesis.
As a catalyst, Tetraisopropyl orthotitanate can facilitate organic reactions in a fast and efficient manner.
Tetraisopropyl orthotitanate is used as a precursor for the production of high-quality titanium dioxide pigment used in paints, cosmetics, and food products.

Tetraisopropyl orthotitanate is used as a starting material for the synthesis of other titanium compounds.
Tetraisopropyl orthotitanate can also act as an adhesion promoter, improving the adhesion of coatings and adhesives to various substrates.
Overall, the features and benefits of Tetraisopropyl orthotitanate make it a valuable compound in various industries, providing an efficient and versatile solution for the production of high-quality products.

Tetraisopropyl orthotitanate is widely used as a catalyst in the production of various polymers, including polyesters and polyurethanes.
Tetraisopropyl orthotitanate facilitates the polymerization process and helps control the molecular weight and properties of the resulting polymers.
In addition to catalyzing polymerization reactions, Tetraisopropyl orthotitanate also functions as a crosslinking agent.

Tetraisopropyl orthotitanate promotes the formation of crosslinks between polymer chains, improving the mechanical strength, thermal stability, and other properties of the final polymer products.
Tetraisopropyl orthotitanate is often employed as an adhesion promoter in adhesive formulations.
Tetraisopropyl orthotitanate enhances the bonding strength between substrates by promoting adhesion at the interface, leading to improved performance and durability of adhesive joints.

Due to its reactivity with hydroxyl-containing surfaces, tetraisopropyl orthotitanate is used as a surface modifier for materials such as glass, ceramics, and metals.
Tetraisopropyl orthotitanate can modify the surface properties, such as wettability and adhesion, to improve compatibility with other materials or coatings.
Tetraisopropyl orthotitanate is a key precursor in sol-gel processing, a versatile technique for producing thin films, coatings, and nanostructured materials.

Tetraisopropyl orthotitanate undergoes hydrolysis and condensation reactions to form a sol, which can then be processed into various forms, including thin films and nanoparticles.
In photocatalytic applications, tetraisopropyl orthotitanate is used as a precursor for titanium dioxide (TiO2) nanoparticles, which exhibit photocatalytic activity under UV irradiation.
These nanoparticles find applications in environmental remediation, water purification, and self-cleaning coatings.

Tetraisopropyl orthotitanate is employed in textile treatments as a sizing agent or finishing agent to improve the fabric's dimensional stability, wrinkle resistance, and dye affinity.
In some formulations, Tetraisopropyl orthotitanate may serve as a fuel additive to improve combustion efficiency and reduce emissions in internal combustion engines.
Tetraisopropyl orthotitanate is employed in the preparation of nanocomposites, where it serves as a coupling agent or surface modifier to enhance the dispersion and interfacial adhesion of nanoparticles within the polymer matrix.

This improves the mechanical, thermal, and barrier properties of the nanocomposite materials.
In the construction industry, Tetraisopropyl orthotitanate is sometimes used as an admixture in concrete formulations to enhance the workability, strength, and durability of concrete.
Tetraisopropyl orthotitanate can act as a plasticizer or water reducer, reducing the water-cement ratio and improving the overall performance of concrete mixes.

Melting point: 14-17 °C(lit.)
Boiling point: 232 °C(lit.)
Density: 0.96 g/mL at 20 °C(lit.)
vapor pressure: 60.2hPa at 25℃
refractive index: n20/D 1.464(lit.)
Flash point: 72 °F
storage temp.: Flammables area
solubility: Soluble in anhydrous ethanol, ether, benzene and chloroform.
form: Liquid
Specific Gravity: 0.955
color: Colorless to pale yellow
Water Solubility: HYDROLYSIS
FreezingPoint: 14.8℃
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity 7: reacts slowly with moisture/water
Merck: 14,9480
BRN: 3679474
Stability: Stable, but decomposes in the presence of moisture. Incompatible with aqueous solutions, strong acids, strong oxidizing agents. Flammable.
InChIKey: VXUYXOFXAQZZMF-UHFFFAOYSA-N
LogP: 0.05

Tetraisopropyl orthotitanate is utilized in ceramic processing as a sintering aid and densification promoter.
Tetraisopropyl orthotitanate can enhance the densification of ceramic powders during sintering, leading to improved mechanical properties and reduced porosity in the final ceramic products.
In the ink and coating industries, tetraisopropyl orthotitanate is employed as an additive to improve the adhesion, durability, and scratch resistance of printed or coated surfaces.

Tetraisopropyl orthotitanate helps enhance the performance of inks and coatings on various substrates, including paper, plastics, and metals.
Due to its ability to form protective coatings on metal surfaces, tetraisopropyl orthotitanate is used as an anticorrosive agent in paints, coatings, and metal treatment formulations.
Tetraisopropyl orthotitanate can inhibit the corrosion of metal substrates by providing a barrier against moisture and corrosive agents.

Tetraisopropyl orthotitanate has potential applications in the biomedical field, particularly in biomaterials and tissue engineering.
Tetraisopropyl orthotitanate can be incorporated into scaffold materials to improve their mechanical properties and biocompatibility for tissue regeneration and implantable medical devices.
In the production of photovoltaic devices such as solar cells, tetraisopropyl orthotitanate is utilized as a precursor for the fabrication of transparent conductive coatings or as a dopant in semiconductor layers.

Tetraisopropyl orthotitanate plays a crucial role in improving the efficiency and performance of photovoltaic devices.
Tetraisopropyl orthotitanate can act as a fire retardant additive in polymers and coatings to enhance their flame resistance and reduce the risk of ignition or spread of fire.
Tetraisopropyl orthotitanate can inhibit the combustion process and decrease the release of toxic gases during combustion.

Tetraisopropyl orthotitanate is used as a linker or precursor in the synthesis of metal-organic frameworks (MOFs), which are porous materials with potential applications in gas storage, catalysis, and separations.
Catalyst for the synthesis of acyclic epoxy alcohols and allylic epoxy alcohols.
Useful for diastereoselective reduction of alpha-fluoroketones.

Catalyzes the asymmetric allylation of ketones.
Reagent for the synthesis of cyclopropylamines from aryl and alkenyl nitriles.
Useful for racemic and/or enantioselective addition of nucleophiles to aldehydes, ketones and imines.

Catalytic intramolecular formal [3+2] cycloaddition.
Catalyst for the synthesis of cyclopropanols from esters and organomagnesium reagents
Tetraisopropyl orthotitanate is utilized in the preparation of hydrophobic coatings for various surfaces, including glass, metal, and concrete.

These coatings repel water and prevent moisture ingress, thereby providing protection against corrosion, staining, and weathering.
As a metal surface treatment agent, Tetraisopropyl orthotitanate is applied to metal substrates to enhance their adhesion, corrosion resistance, and paintability.
Tetraisopropyl orthotitanate promotes bonding between the metal surface and organic coatings, improving the overall performance and longevity of metal-based products.

In some formulations, Tetraisopropyl orthotitanate functions as a silane coupling agent, facilitating adhesion between organic and inorganic materials.
Tetraisopropyl orthotitanate can improve the compatibility and bonding strength between polymers and mineral fillers or reinforcements in composite materials.
Tetraisopropyl orthotitanate is used in textile printing processes as a fixing agent or binder for pigments and dyes.

Tetraisopropyl orthotitanate helps improve the color fastness, wash resistance, and durability of printed designs on fabric surfaces.
In the field of energy storage and conversion, Tetraisopropyl orthotitanate is investigated for its potential use as an electrolyte additive in proton exchange membrane fuel cells (PEMFCs).
Tetraisopropyl orthotitanate may improve the proton conductivity and stability of the electrolyte membrane, leading to enhanced fuel cell performance.

Tetraisopropyl orthotitanate can serve as a support material or modifier for catalytic systems used in various chemical reactions.
Tetraisopropyl orthotitanate may enhance the catalytic activity, selectivity, and stability of supported catalysts, particularly in heterogeneous catalysis.
The pronounced tendency of orthotitanates to react with the active hydrogen atoms of hydroxy, amino, amido, carboxyl and thiol groups to crosslink and form thin amorphous TiO 2 layers can be modified in a variety of ways to glass, metal and polymer surfaces , such as B. as an adhesion promoter ( primer ) to increase adhesion , hardness as well as abrasion and scratch resistance, thermal and chemical resistance, light reflection and corrosion resistance.

Such coatings also increase the dispersibility of pigments and fillers in water-based or non-aqueous varnishes and paints and reduce their viscosity .
On the other hand, crosslinking polymers containing hydroxy groups in paints with titanium isopropoxide can also increase the viscosity, adjust the thixotropy of latex paints and improve their adhesion to surfaces.
The crosslinking properties of tetraisopropyl titanate make it an effective additive in papermaking to increase wet strength, in oil drilling aids to control viscosity, and in printing inks to improve adhesion.

Through carefully controlled hydrolytic sol-gel processes or through pyrolytic processes at temperatures above 350 °C, not only thin polymeric TiO 2 films but also micro- and nanoscale TiO 2 particles can be produced from titanium isopropoxide.
Because of their high refractive index and UV absorption, these particles have interesting potential as photocatalysts , in photovoltaics and for applications in lighting and signage.
Tetraisopropyl orthotitanate forms with carboxylic acids , such as. B. Acetic acid non-stoichiometric oligomeric titanium acylates of the approximate composition Ti(OOCMe) 2 (OCHMe 2 ) 2 , which react with alkaline earth metal carbonates to form the corresponding alkaline earth metal titanates, which are of interest for the construction of multilayer ceramic capacitors and thermistors because of their ferroelectric properties are.

Tetraisopropyl orthotitanate is a chemical compound commonly used as a catalyst, cross-linking agent, or surface modifier in various industries.
Tetraisopropyl orthotitanate finds applications in the production of coatings, adhesives, sealants, and plastics.
Tetraisopropyl orthotitanate acts as a drying agent for paints and inks, enhancing their durability and performance.

Safety precautions should be taken when handling Tetraisopropyl orthotitanate as it is flammable and may cause eye and skin irritation.
Tetraisopropyl orthotitanate should be stored in a tightly sealed container in a well-ventilated area away from heat sources or oxidizing agents.
Environmental impact data indicates that it may have adverse effects on aquatic organisms if not properly managed or disposed of. Not for human consumption.

Uses:
Catalyst especially for asymmetric induction in organic syntheses; in preparation of nanosized TiO2.
Tetraisopropyl orthotitanate is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films.
Tetraisopropyl orthotitanate is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes.

Tetraisopropyl orthotitanate is an active component of Sharpless epoxidation as well as involved in the synthesis of chiral epoxides.
In Kulinkovich reaction, Tetraisopropyl orthotitanate is involved as a catalyst in the preparation of cyclopropanes.
Tetraisopropyl orthotitanate can be used as a precursor for ambient conditions vapour phase deposition such as infiltration into polymer thin films.

Tetraisopropyl orthotitanate is used as a precursor for the production of titanium dioxide (TiO2), a white pigment widely used in the paint, cosmetic, and food industries.
Tetraisopropyl orthotitanate is used as a catalyst in organic synthesis reactions, such as the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Tetraisopropyl orthotitanate is used as an initiator for the polymerization of vinyl monomers and as a coupling agent for polymer-polymer and polymer-inorganic material interactions.

Tetraisopropyl orthotitanate can act as an adhesion promoter, improving the adhesion of coatings and adhesives to various substrates.
Tetraisopropyl orthotitanate is used in the production of thin-film capacitors and in the fabrication of metal-insulator-metal capacitors.
Tetraisopropyl orthotitanate can be used for the surface treatment of metals, ceramics, and glass to improve their properties, such as corrosion resistance and adhesion.

Tetraisopropyl orthotitanate, is commonly used as a cross-linking agent and catalyst in the glass industry.
Tetraisopropyl orthotitanate is often used as a cross-linking agent in anti-reflective coatings for glass.
The coating helps to reduce glare and improve visibility, making it ideal for applications like eyeglasses, camera lenses, and flat panel displays.

Tetraisopropyl orthotitanate is also used to create self-cleaning coatings for glass.
When exposed to sunlight, the coating reacts with oxygen to produce free radicals that break down organic matter on the surface of the glass.
This helps to keep the glass clean and reduces the need for manual cleaning.

As I mentioned earlier, Tetraisopropyl orthotitanate is used as a precursor for the synthesis of titanium dioxide (TiO2) nanoparticles.
These nanoparticles are used as pigments in glass and ceramic applications, providing improved optical properties and color saturation.
They are often used in products like decorative glassware, ceramic tiles, and automotive glass.

Tetraisopropyl orthotitanate can also be used to create scratch-resistant coatings for glass.
When added to the coating, Tetraisopropyl orthotitanate reacts with the hydroxyl groups on the surface of the glass to create a durable, cross-linked network.
This network helps to protect the glass from scratches, abrasion, and chemical damage, making it ideal for applications like smartphone screens and protective eyewear.

Tetraisopropyl orthotitanate is utilized in the production of nanocomposites, where it serves as a coupling agent to improve the dispersion and interfacial adhesion of nanoparticles within the polymer matrix.
In the construction industry, Tetraisopropyl orthotitanate is sometimes used as an admixture in concrete formulations to enhance the strength and durability of concrete.
Tetraisopropyl orthotitanate is used in the formulation of hydrophobic coatings to provide water repellency and protection against moisture ingress.

Tetraisopropyl orthotitanate is applied to metal surfaces as a treatment agent to enhance adhesion, corrosion resistance, and paintability.
Tetraisopropyl orthotitanate functions as a silane coupling agent to improve bonding between organic and inorganic materials in composite formulations.
Tetraisopropyl orthotitanate is utilized in textile printing processes as a fixing agent to improve color fastness and wash resistance.

In the field of energy storage, Tetraisopropyl orthotitanate is investigated for its potential use as an electrolyte additive in fuel cells to enhance performance.
Tetraisopropyl orthotitanate can serve as a support material for catalysts, enhancing their catalytic activity and stability in chemical reactions.
Tetraisopropyl orthotitanate, is commonly used in the ink industry as a cross-linking agent and as a catalyst for polymerization reactions.

Tetraisopropyl orthotitanate is often used as a cross-linking agent in UV-curable inks. When exposed to UV light, the ink undergoes a polymerization reaction that cross-links the ink molecules and hardens the ink film.
Tetraisopropyl orthotitanate can be added to the ink formulation to promote cross-linking and improve the ink’s adhesion, durability, and resistance to abrasion and chemical attack.
Tetraisopropyl orthotitanate is also used as a dispersant in pigment dispersions for ink formulations.

Tetraisopropyl orthotitanate helps to stabilize the pigment particles and prevent them from settling out of the ink.
This improves the color consistency and print quality of the ink.
Tetraisopropyl orthotitanate can be used as a catalyst for the polymerization of acrylic resins used in metal printing.

The resin is applied to the metal substrate as an ink and then cured using Tetraisopropyl orthotitanate as a catalyst.
This creates a durable and scratch-resistant coating on the metal surface.
Tetraisopropyl orthotitanate can be added to inkjet inks as a cross-linking agent to improve the ink’s adhesion and durability on various substrates, such as paper, plastic, and metal.

Overall, Tetraisopropyl orthotitanate is a valuable tool in the ink industry, helping to improve the performance and quality of ink formulations.
Tetraisopropyl orthotitanate is ability to promote cross-linking, stabilize pigments, and catalyze polymerization reactions makes it a versatile material for ink manufacturers.
Tetraisopropyl orthotitanate is used as a catalyst in the production of polyesters and polyurethanes, where it aids in controlling the polymerization process and improving the properties of the final polymers.

Tetraisopropyl orthotitanate acts as a crosslinking agent in polymer formulations, enhancing the mechanical strength and thermal stability of polymers.
Tetraisopropyl orthotitanate is utilized as an adhesion promoter in coatings and adhesives to improve the bonding between substrates and coatings.
Tetraisopropyl orthotitanate is used as a surface modifier to enhance the adhesion and compatibility of coatings on various substrates such as glass, ceramics, and metals.

Tetraisopropyl orthotitanate is employed in sol-gel processing to produce thin films, coatings, and nanostructured materials with controlled properties.
Tetraisopropyl orthotitanate is a precursor for titanium dioxide nanoparticles used in photocatalytic applications such as water purification and self-cleaning coatings.
Tetraisopropyl orthotitanate is used in textile treatments to improve dimensional stability and wrinkle resistance.

Tetraisopropyl orthotitanate aids in ceramic processing by promoting densification during sintering.
Tetraisopropyl orthotitanate enhances the performance of inks and coatings on various substrates.
Tetraisopropyl orthotitanate is used in paints and coatings as an anticorrosive agent to protect metal surfaces.

Tetraisopropyl orthotitanate finds applications in biomaterials and tissue engineering.
Tetraisopropyl orthotitanate is used in the production of solar cells to improve efficiency.

Tetraisopropyl orthotitanate can act as a fire retardant additive in polymers and coatings.
Tetraisopropyl orthotitanate is utilized in the synthesis of MOFs for gas storage and separations.

Health Hazard:
Inhalation or contact with material may irritate or burn skin and eyes.
Fire may produce irritating, corrosive and/or toxic gases.

Vapors may cause dizziness or suffocation.
Runoff from fire control or dilution water may cause pollution.

Safety Profile:
Direct contact with Tetraisopropyl orthotitanate may cause irritation to the skin, resulting in redness, itching, or dermatitis.
Prolonged or repeated exposure can exacerbate these effects.
Contact with the eyes can lead to irritation, redness, and discomfort.

Eye contact should be avoided, and appropriate eye protection should be worn when handling Tetraisopropyl orthotitanate.
Inhalation of vapor or aerosols may irritate the respiratory tract, leading to coughing, shortness of breath, or throat irritation.
Adequate ventilation and respiratory protection should be used to minimize exposure.

Tetraisopropyl orthotitanate is flammable and may form flammable vapor-air mixtures.
Tetraisopropyl orthotitanate should be stored and handled away from ignition sources, and appropriate fire precautions should be taken.
Tetraisopropyl orthotitanate can react with water to produce flammable hydrogen gas.

Tetraisopropyl orthotitanate should be kept away from moisture and water sources to prevent accidental reactions.
Spills or releases of Tetraisopropyl orthotitanate can pose environmental hazards, particularly if it contaminates waterways or soil.
Tetraisopropyl orthotitanate may have adverse effects on aquatic organisms and ecosystems.

Tetraisopropyl Titanate is colorless to light yellow transparent liquid.
Tetraisopropyl Titanate is water rapid hydrolysis, soluble in alcohol, ether, ketone, benzene and other organic solvents.
Non-polymerized in non-polar solvents, Tetraisopropyl Titanate is a tetrahedral diamagnetic molecule.


CAS Number: 546-68-9
EC Number: 208-909-6
MDL number: MFCD00008871
Chemical formula: C12H28O4Ti


Tetraisopropyl Titanate smokes in moist air.
Tetraisopropyl Titanate, isopropyl alcohol, and liquid ammonia were heated and dissolved in toluene as a solvent to undergo an esterification reaction.
The reaction product was filtered off by-product ammonium chloride by suction, and the product was obtained by distillation.


Tetraisopropyl Titanate appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol.
Tetraisopropyl Titanate has about the same density as water. Tetraisopropyl Titanate's vapors heavier than air.
Tetraisopropyl Titanate is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.


Tetraisopropyl Titanate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Tetraisopropyl Titanate has a complex structure.


In crystalline state, Tetraisopropyl Titanate is a tetramer.
Non-polymerized in non-polar solvents, Tetraisopropyl Titanate is a tetrahedral diamagnetic molecule.
Tetraisopropyl Titanate has a complex structure.


In crystalline state, Tetraisopropyl Titanate is a tetramer.
Non-polymerized in non-polar solvents, Tetraisopropyl Titanate is a tetrahedral diamagnetic molecule.
Tetraisopropyl Titanate is an alkoxy titanate with a high level of reactivity.


Tetraisopropyl Titanate is a type of very lively primary alcohol titanium oxide.
Tetraisopropyl Titanate hydrolyzes when contacted with moisture in air.
Tetraisopropyl Titanate is a 100% active tetra-isopropyl titanate in liquid form.


Tetraisopropyl Titanate is a catalyst.
Tetraisopropyl Titanate is added to the formulation as an adhesion promoter and as the base material in the formation of sol-get systems or nanoparticle systems or products.


Tetraisopropyl Titanate synthesizes dispersants, titanate coupling and cross-linking agents.
Tetraisopropyl Titanate is an organic titanate that has a wide range of applications across several industries.
Tetraisopropyl Titanate is a colorless, slighty yellowish liquid that is very sensitive to moisture.


Tetraisopropyl Titanate, also commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4.
Tetraisopropyl Titanate is a diamagnetic tetrahedral molecule. Tetraisopropyl Titanate is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.


The structures of the titanium alkoxides are often complex.
Crystalline Tetraisopropyl Titanate is tetrameric with the molecular formula Ti4(OCH3)16.
Alkoxides derived from bulkier alcohols such as isopropyl alcohol aggregate less.
Tetraisopropyl Titanate is mainly a monomer in nonpolar solvents.



USES and APPLICATIONS of TETRAISOPROPYL TITANATE:
Tetraisopropyl Titanate is used by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Tetraisopropyl Titanate is used in the following products: pH regulators and water treatment products, laboratory chemicals and water treatment chemicals.
Tetraisopropyl Titanate is used in the following areas: health services and scientific research and development.


Tetraisopropyl Titanate is used for the manufacture of: chemicals.
Release to the environment of Tetraisopropyl Titanate can occur from industrial use: manufacturing of the substance.
Other release to the environment of Tetraisopropyl Titanate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Tetraisopropyl Titanate is used in the following products: adhesives and sealants, coating products and lubricants and greases.
Release to the environment of Tetraisopropyl Titanate can occur from industrial use: formulation of mixtures.
Tetraisopropyl Titanate is used in the following products: polymers, fuels, coating products, lubricants and greases, pH regulators and water treatment products and laboratory chemicals.


Tetraisopropyl Titanate has an industrial use resulting in manufacture of another substance (use of intermediates).
Tetraisopropyl Titanate is used in the following areas: health services and scientific research and development.
Tetraisopropyl Titanate is used for the manufacture of: chemicals and plastic products.


Release to the environment of Tetraisopropyl Titanate can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and in processing aids at industrial sites.
Release to the environment of Tetraisopropyl Titanate can occur from industrial use: manufacturing of the substance.


Tetraisopropyl Titanate for the esterification reaction is used for the transesterification reaction of esters such as acrylic acid and the polymerization of epoxy resin, phenolic plastic, silicone resin, polybutadiene, PP and PE.
Tetraisopropyl Titanate can also be used as raw materials for the pharmaceutical industry and the preparation of metal and rubber, metal and plastic adhesives.


Tetraisopropyl Titanate can also be used as surface modifier, adhesion promoter and paraffin and oil additives.
Isopropyl titanate, also known as Tetraisopropyl Titanate, titanium tetraisopropoxide is the isopropoxide of titanium (IV), used in organic synthesis and materials science.


Isopropyl titanate, also known as Tetraisopropyl Titanate, titanium tetraisopropoxide is the isopropoxide of titanium (IV), used in organic synthesis and materials science.
Tetraisopropyl Titanate is used for ester exchange reaction


Tetraisopropyl Titanate is used as an auxiliary agent and chemical product intermediate
Tetraisopropyl Titanate is used to make adhesives, used as a catalyst for transesterification and polymerization reactions
Tetraisopropyl Titanate binders for preparing metals and rubber, metals and plastics, and also used as catalysts for transesterification and polymerization reactions and raw materials for the pharmaceutical industry.


Tetraisopropyl Titanate is used catalyst for esterification reaction, transesterification reaction of acrylic acid and other esters.
Tetraisopropyl Titanate is used as Ziegler (Ziegler Natta) catalyst in polymerization reactions such as epoxy resin, phenolic plastic, silicone resin, polybutadiene, etc.
Tetraisopropyl Titanate has high stereoselectivity.


In the paint, a variety of polymers or resins play a cross-linking role, improve the anti-corrosion ability of the coating, etc., and also promote the adhesion of the coating to the surface.
Tetraisopropyl Titanate can be directly used as a material surface modifier, and adhesive promoter.


Tetraisopropyl Titanate is used polymerization catalyst.
Tetraisopropyl Titanate is used for transesterification.
Tetraisopropyl Titanate can adhere paint, rubber and plastic to metal.


Tetraisopropyl Titanate is used as an additive for the Sharpless asymmetric epoxidation reaction of allyl alcohol.
Tetraisopropyl Titanate is used as a catalyst for transesterification reaction with various alcohols under neutral conditions.
Tetraisopropyl Titanate can be formed by a sol-gel two-step method New metal oxide/phosphonate hybrid.


Tetraisopropyl Titanate is used as a raw material for barium strontium titanate film.
Tetraisopropyl Titanate is used to prepare porous titanosilicate, which is a potential ion exchange material for removing radioactive waste.
Tetraisopropyl Titanate is used to form heterogeneous supramolecules composed of TiO2 nanocrystals-violet essence electron acceptor complexes.


Tetraisopropyl Titanate has been proved that it can undergo light-induced electron transfer
Tetraisopropyl Titanate is mainly used for transesterification and condensation reactions in organic synthesis Catalyst.
Tetraisopropyl Titanate is often used as a precursor to prepare titanium dioxide (TiO2).


A new metal oxide/phosphonate hybrid can be formed from titanium tetraisopropoxide by sol-gel two-step method.
The raw material of barium strontium titanate film.
Tetraisopropyl Titanate is used to prepare porous titanosilicates, which are potential ion exchange materials for the removal of radioactive wastes.


Tetraisopropyl Titanate is used to form heterogeneous supramolecules composed of TiO2 nanocrystals-violet essence electron acceptor complexes, which have been shown to be capable of light-induced electron transfer.
Tetraisopropyl Titanate is mainly used as catalyst in esterification reaction or transesterification,also being used as catalyst of polyolefin.


Tetraisopropyl Titanate can be used to improve the adherence and crosslinking of resin having alcohol group or carboxyl group, used in heat resistant and corrosion resistant coating.
Tetraisopropyl Titanate also can be used in the manufacture of glass and glass fiber.


Tetraisopropyl Titanate is most commonly used as a Lewis acid and a Ziegler–Natta catalyst.
Tetraisopropyl Titanate is typically used as a metal catalyst in producing polyolefins and polycarbonate.
Tetraisopropyl Titanate improves the yield of olefin polymerization, esterification, condensation, and addition reactions while eliminating unwanted byproducts.


Compared to other Tyzor titanates, Tetraisopropyl Titanate is highly moisture sensitive and will decompose when exposed to water.
Tetraisopropyl Titanate is useful as a replacement for tin, organostannanes, and sulfuric acid in esterification reactions when toxicity reduction is desired.
Tetraisopropyl Titanate is even more efficient than sulfuric acid in esterification reactions.


When added to solvent-based paints, Tetraisopropyl Titanate will cross-link hydroxyl and carboxyl functional polymers to increase chemical and heat resistance.
Like many other Tyzor grades, Tetraisopropyl Titanate can also be used to coat metal and glass surfaces with a thin polymeric film of titanium dioxide.
This can promote adhesion, improve surface hardness, increase light reflection, and add coloring effects.


Tetraisopropyl Titanate is used for heat-resistant surface coatings in paints, lacquers, and plastics.
Tetraisopropyl Titanate is used for hardening and cross-linking of epoxy, silicon, urea, melamine, and terephthalate resins and adhesives.
Tetraisopropyl Titanate is used for adhesion of paints, rubber, and plastics to metals.


Tetraisopropyl Titanate is also used in catalysts, glass surface treatments, flue gas sorbents, controlled-release pesticides, and dental compositions (to bond to enamel).
Tetraisopropyl Titanate is used to make nano-sized titanium dioxide.
Tetraisopropyl Titanate is suitable for primer coatings.


Tetraisopropyl Titanate can be used directly or in directly as a catalyst or catlyst additive,as a coating primer or added to formulation as a adhesion promoter and as the base material in the formation fo sol-get systems or nanoparticle systems or products.
Tetraisopropyl Titanate can be used as sharpless oxidation catalyst.


Synthesize all kinds of titanate coupling agent, cross-linking agent and dispersant.
Tetraisopropyl Titanate is used as a catalyst for esterification reaction and transesterification reaction of esters such as acrylic acid.
Tetraisopropyl Titanate is used as Ziegler Natta catalyst in the polymerization of epoxy resin, phenolic plastic, silicone resin, polybutadiene, PP, PE, etc.


Tetraisopropyl Titanate has high stereoselectivity and benefits.
Tetraisopropyl Titanate is used in paints to cross-link a variety of polymers or resins, improve the anti-corrosion ability of the coating, etc., and also promote the adhesion of the coating to the surface.


Tetraisopropyl Titanate can also be directly used as material surface modifier, adhesion promoter, primer, and the adhesion of topcoat to materials.
Tetraisopropyl Titanate decomposes at high temperature (300-650℃) to form a hard and smooth titanium dioxide film layer.
Tetraisopropyl Titanate can be used as an esterification catalyst for plasticizers, polyesters, methacrylic esters, resins, polycarbonates, polyolefins and RTV silicone sealants.


Tetraisopropyl Titanate can also be used for coating chemicals as a cross linker for wire enamel varnish, glass and zinc flake coatings.
Tetraisopropyl Titanate is most suitable for use in the glass and glass fiber manufacturing.
Tetraisopropyl Titanate is used as bond agent between metal and rubber , or metal and plastic.


Tetraisopropyl Titanate is used catalyst to the esterification exchange reaction or polymerization reaction.
Tetraisopropyl Titanate is used as coupling agent.
This alkoxide of titanium(IV), Tetraisopropyl Titanate, is used in organic synthesis and materials science.


Prochiral thioethers are oxidized enantioselectively using a catalyst derived from Ti(O-i-Pr)4.
Tetraisopropyl Titanate belongs to the product group of organic titanates, which are known to be highly reactive organics that can be used in a broad range of processes and applications.


Tetraisopropyl Titanate is also used as a catalyst in the preparation of certain cyclopropanes in the Kulinkovich reaction.
Tetraisopropyl Titanate is used for the preparation of adhesives, as a catalyst for transesterification and polymerization.
Tetraisopropyl Titanate can be used as a precursor for ambient conditions vapour phase deposition such as infiltration into polymer thin films.


-Applications of Tetraisopropyl Titanate:
*Catalyst to produce plasticizers, polyesters and methacrylic esters
*Adhesion promoter
*Cross-linking for polymers
*Coatings
*Surface modification (metal, glass)



USAGE OF TETRAISOPROPYL TITANATE:
(1). Exchange Reaction for Esters
(2). Tetraisopropyl Titanate is used as additives and intermediates in chemical products
(3). Tetraisopropyl Titanate is used to make adhesives and as catalysts for transesterification and polymerization
(4). Tetraisopropyl Titanate can be used to prepare adhesives for metal and rubber, metal and plastics, catalysts for transesterification and polymerization, and raw materials for pharmaceutical industry.
(5). Tetraisopropyl Titanate is mainly used as catalyst for transesterification and condensation in organic synthesis.

Tetraisopropyl Titanate is often used as precursor to prepare titanium dioxide (titanium dioxide).
A new type of metal oxide / phosphonate hybrids can be formed from four isopropanol titanium by sol-gel two step process.
Raw materials for barium strontium titanate thin films.

Porous titanium silicate is a potential ion exchange material for the removal of radioactive waste.
Photoinduced electron transfer has been demonstrated to occur in heterogeneous supramolecules consisting of nanocrystalline titanium dioxide and viologen electron acceptor complexes.



FEATURES AND BENEFITS OF TETRAISOPROPYL TITANATE:
*High chemical reactivity
*Lewis acid catalyst
*Ziegler–Natta catalyst
*Moisture scavenger
*Low toxicity
*Cross-linking agent for hydroxyl and carboxyl functional polymers
*Increases heat and chemical resistance
*Forms polymeric TiO2 films
*Promotes adhesion
*Increases light reflection of glass



PROPERTIES OF TETRAISOPROPYL TITANATE:
Tetraisopropyl Titanate reacts with water to deposit titanium dioxide:
Ti{OCH(CH3)2}4 + 2 H2O → TiO2 + 4 (CH3)2CHOH
This reaction is employed in the sol-gel synthesis of TiO2-based materials in the form of powders or thin films.
Typically water is added in excess to a solution of the alkoxide in an alcohol.
The composition, crystallinity and morphology of the inorganic product are determined by the presence of additives (e.g. acetic acid), the amount of water (hydrolysis ratio), and reaction conditions.



NAMING OF TETRAISOPROPYL TITANATE:
Tetraisopropyl Titanate is a widely used item of commerce and has acquired many names in addition to those listed in the table.
A sampling of the names include: titanium(IV) i-propoxide, isopropyl titanate, tetraisopropyl titanate, tetraisopropyl orthotitanate, titanium tetraisopropylate, orthotitanic acid tetraisopropyl ester, Isopropyl titanate(IV), titanic acid tetraisopropyl ester, isopropyltitanate, titanium(IV) isopropoxide, titanium tetraisopropoxide, iso-propyl titanate, titanium tetraisopropanolate, tetraisopropoxytitanium(IV), tetraisopropanolatotitanium, tetrakis(isopropoxy) titanium, tetrakis(isopropanolato) titanium, titanic acid isopropyl ester, titanic acid tetraisopropyl ester, titanium isopropoxide, titanium isopropylate, tetrakis(1-methylethoxy)titanium.



PRODUCTION METHOD OF TETRAISOPROPYL TITANATE:
Tetraisopropyl Titanate, isopropyl alcohol and liquid ammonia are esterified in toluene, absorbed and filtered to remove by-product ammonium chloride, and then distilled to obtain the finished product.
Raw material consumption (kg/t) toluene (98%) 1000 titanium tetrachloride (99%) 1500 isopropanol (98%) 1600 liquid ammonia 1400.



PREPARATION OF TETRAISOPROPYL TITANATE:
Tetraisopropyl Titanate is prepared by treating titanium tetrachloride with isopropanol.
Hydrogen chloride is formed as a coproduct:
TiCl4 + 4 (CH3)2CHOH → Ti{OCH(CH3)2}4 + 4 HCl



PHYSICAL and CHEMICAL PROPERTIES of TETRAISOPROPYL TITANATE:
Chemical formula: C12H28O4Ti
Molar mass: 284.219 g·mol−1
Appearance: colorless to light-yellow liquid
Density: 0.96 g/cm3
Melting point: 17 °C (63 °F; 290 K) approximation
Boiling point: 232 °C (450 °F; 505 K)
Solubility in water: Reacts to form TiO2
Solubility: soluble in ethanol, ether, benzene, chloroform
Refractive index (nD): 1.46
Molecular Formula: C12H28O4Ti
Molar Mass: 284.22
Density: 0.96 g/mLat 20°C(lit.)
Melting Point: 14-17°C(lit.)
Boling Point: 232°C(lit.)
Flash Point: 72°F
Water Solubility: HYDROLYSIS
Solubility: Soluble in anhydrous ethanol, ether, benzene and chloroform.
Vapor Presure: 60.2hPa at 25℃

Appearance: Liquid
Specific Gravity: 0.955
Color: Colorless to pale yellow
Merck: 14,9480
BRN: 3679474
Stability: Stable, but decomposes in the presence of moisture.
Incompatible with aqueous solutions, strong acids, strong oxidizing agents.
Sensitive 7: reacts slowly with moisture/water
Refractive Index: n20/D 1.464(lit.)
Character: light yellow liquid, smoke in humid air.
boiling point: 102~104 ℃
freezing point: 14.8 ℃
relative density: 0.954g/cm3
refractive index: 1.46
Physical state: liquid
Color: light yellow
Odor: alcohol-like
Melting point/freezing point:
Melting point/range: 14 - 17 °C
Initial boiling point and boiling range: 232 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point: 41 °C
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 3 mPa.s at 25 °C
Water solubility insoluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: 1,33 hPa at 63 °C
Density: 0,96 g/mL at 20 °C
Relative density: 0,96 at 25 °C
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available



FIRST AID MEASURES of TETRAISOPROPYL TITANATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAISOPROPYL TITANATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TETRAISOPROPYL TITANATE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAISOPROPYL TITANATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
required
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TETRAISOPROPYL TITANATE:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Handle under nitrogen, protect from moisture.
Store under nitrogen.
Keep container tightly closed in a dry and well-ventilated place.
Keep away from heat and sources of ignition.
Hydrolyzes readily.
Handle and store under inert gas.



STABILITY and REACTIVITY of TETRAISOPROPYL TITANATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
May decompose on exposure to moist air or water.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
Titanium isopropoxide
Tetraisopropyl titanate
Titanium(IV) i-propoxide
Titanium tetraisopropoxide
Tetraisopropyl orthotitanate
Titanium (IV) isopropoxide
Tetraisopropyl Orthotitanate
Isopropyl Titanate
2-Propanol, titanium(4+) salt
Tetraisopropyl titanate
Titanium tetraisopropoxide
Tetraisopropoxy titanium
TTIP
Tetraisopropyl orthotitanate
TPT
Isopropyltitanate
ISOPROPYL TITANATE
TITANIUM ISOPROPOXIDE
Titanium isopropoxide
ISOPROPYL TITANATE(IV)
TITANIUM ISO-PROPYLATE
Tetraisopropyl titanate
Titanium(IV) i-propoxide
Titanium(IV) isopropoxide
TITANIUM (IV) I-PROPOXIDE
TITANIUM(IV) ISOPROPOXIDE
Titanium tetraisopropoxide
Tetraisopropoxytitanium(IV)
tetraisopropyl orthotitanate
TITANIUM(IV) TETRAISOPROPOXIDE
TITANIUM (IV) TETRA-I-PROPOXIDE
titanium(4+) tetrapropan-2-olate
2-Propanol, titanium(4+) salt
A 1 (titanate)
Isopropyl alcohol titanium(4+) salt
Isopropyl alcohol, titanium salt
Isopropyl orthotitanate
Isopropyl titanate(IV)
Isopropyl titanate(IV) ((C3H7O)4Ti)
Orgatix TA 10
TA 10
Tetraisopropanolatotitanium
Tetraisopropoxide titanium
Tetraisopropoxytitanium
Tetraisopropoxytitanium(IV)
Tetraisopropyl orthotitanate
Tetrakis(isopropoxy)titanium
Tetrakis(isopropanolato)titanium
Ti Isopropylate
Tilcom TIPT
Titanic acid isopropyl ester
Titanic acid tetraisopropyl ester
Titanic(IV) acid, tetraisopropyl ester
Titanium isopropoxide (Ti(OC3H7)4)
Titanium isopropylate
Titanium isopropylate (VAN)
Titanium tetraisopropoxide
Titanium tetraisopropylate
Titanium tetrakis(isopropoxide)
Titanium(4+) isopropoxide
Titanium(IV) isopropoxide
Titanium, tetrakis(1-methylethoxy)-
Tyzor TPT
UN2413
Titanium (IV) isopropoxide
Tetraisopropyl Orthotitanate
Isopropyl Titanate
2-Propanol, titanium(4+) salt
Tetraisopropyl titanate
Titanium tetraisopropoxide
Tetraisopropoxy titanium
tetraisopropyl orthotitanate
Titanium tetraisopropoxide
Tetraisopropyl titanate
Isopropyltitanate
Titanium isopropoxide
Titanium(IV) i-propoxide
Tetraisopropoxytitanium(IV)
TITANIUM ISO-PROPYLATE
titanium(4+) tetrapropan-2-olate
propan-2-ol - titanium (4:1)
TPT
ISOPROPYL TITANATE
Titanium tetraisopropanolate
Titanium tetraisopropylate
Isopropyl Alcohol Titanium(4+)
Salt Titanium Isopropoxide (Ti(OC3H7)4) (7CI)
5N
5N (titanate)
A 1
A 1 (titanate)
AKT 872
Bistrater H-NDH 510C
Isopropyl Orthotitanate
Isopropyl Titanate(IV) ((C3H7O)4Ti)
NDH 510C
Orgatix TA 10
TA 10
TIPT
TPT
TPTA 1
Tetraisopropanolatotitanium
Tetraisopropoxytitanium
Tetraisopropoxytitanium(IV)
Tetraisopropyl Orthotitanate
Tetraisopropyl Titanate
Tetrakis(isopropanolato)titanium
Tetrakis(isopropoxy)titanium
Tetrakis(isopropylato)titanium(IV)
Tetrakis(isopropyloxy)titanium
Tilcom TIPT
Titaium tetraisopropoxide
Titanium Isopropoxide
Titanium Isopropylate
Titanium Tetraisopropoxide
Titanium Tetraisopropylate
Titanium Tetrakis(iso-propoxide)
Titanium Tetrakis(isopropoxide)
Titanium(4+) Isopropoxide
Titanium(IV) isopropoxide; Tetra
Titanium isopropoxide
Titanium isopropylate
2-Propanol, titanium(4+) salt
Isopropyl alcohol titanium(4+) salt
Isopropyl alcohol, titanium salt
Isopropyl orthotitanate
Isopropyl titanate(IV)
Isopropyl titanate(IV) ((C3H7O)4Ti)
Orgatix TA 10
Tetraisopropanolatotitanium
Tetraisopropoxide titanium
Tetraisopropoxytitanium
Tetraisopropoxytitanium(IV)
Tetraisopropyl orthotitanate
Tetrakis(isopropoxy)titanium
Tetraksi(isopropanolato)titanium
Ti Isopropylate
Tilcom TIPT
Titanic acid isopropyl ester
Titanic acid tetraisopropyl ester
Titanic(IV) acid, tetraisopropyl ester
Titanium isopropoxide (Ti(OCH7)4)
Titanium isopropylate
Titanium isopropylate (VAN)
Titanium tetra-n-propoxide
Titanium tetraisopropoxide
Titanium tetraisopropylate
Titanium tetrakis(isopropoxide)
Titanium(4+) isopropoxide
Titanium(IV) isopropoxide
Titanium, tetrakis(1-methylethoxy)-

DESCRIPTION:
Tetraisopropyl titanate, also commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4.
This alkoxide of titanium(IV) is used in organic synthesis and materials science.
Tetraisopropyl titanate is a diamagnetic tetrahedral molecule.

CAS Number: 546-68-9
EC Number: 208-909-6

Tetraisopropyl titanate is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.
The structures of the titanium alkoxides are often complex.
Crystalline titanium methoxide is tetrameric with the molecular formula Ti4(OCH3)16.

Alkoxides derived from bulkier alcohols such as isopropyl alcohol aggregate less.
Tetraisopropyl titanate is mainly a monomer in nonpolar solvents.

Tetraisopropyl titanate belongs to the product group of organic titanates, which are known to be highly reactive organics that can be used in a broad range of processes and applications.
Tetraisopropyl titanate is a colorless, slighty yellowish liquid that is very sensitive to moisture.


PREPARATION OF TETRAISOPROPYL TITANATE:
Tetraisopropyl titanate is prepared by treating titanium tetrachloride with isopropanol.
Hydrogen chloride is formed as a coproduct:
TiCl4 + 4 (CH3)2CHOH → Ti{OCH(CH3)2}4 + 4 HCl

Titanium isopropoxide reacts with water to deposit titanium dioxide:
Ti{OCH(CH3)2}4 + 2 H2O → TiO2 + 4 (CH3)2CHOH
This reaction is employed in the sol-gel synthesis of TiO2-based materials in the form of powders or thin films.
Typically water is added in excess to a solution of the alkoxide in an alcohol.

The composition, crystallinity and morphology of the inorganic product are determined by the presence of additives (e.g. acetic acid), the amount of water (hydrolysis ratio), and reaction conditions.
The compound is also used as a catalyst in the preparation of certain cyclopropanes in the Kulinkovich reaction.
Prochiral thioethers are oxidized enantioselectively using a catalyst derived from Ti(O-i-Pr)4.


APPLICATIONS OF TETRAISOPROPYL TITANATE:
Tetraisopropyl titanate can be used as a precursor for ambient conditions vapour phase deposition such as infiltration into polymer thin films
Tetraisopropyl titanate is used as Catalyst to produce plasticizers, polyesters and methacrylic esters
Tetraisopropyl titanate is used as Adhesion promoter

Tetraisopropyl titanate is used as Cross-linking for polymers
Tetraisopropyl titanate is used as Coatings
Tetraisopropyl titanate is used as Surface modification (metal, glass)

USES OF TETRAISOPROPYL TITANATE:
Tetraisopropyl titanate is used for heat-resistant surface coatings in paints, lacquers, and plastics; for hardening and cross-linking of epoxy, silicon, urea, melamine, and terephthalate resins and adhesives; and for adhesion of paints, rubber, and plastics to metals
Tetraisopropyl titanate is Also used in catalysts, glass surface treatments, flue gas sorbents, controlled-release pesticides, and dental compositions (to bond to enamel)
Tetraisopropyl titanate is used to make nano-sized titanium dioxide.


CHEMICAL AND PHYSICAL PROPERTIES OF TETRAISOPROPYL TITANATE:
Chemical formula C12H28O4Ti
Molar mass 284.219 g•mol−1
Appearance colorless to light-yellow liquid
Density 0.96 g/cm3
Melting point 17 °C (63 °F; 290 K) approximation
Boiling point 232 °C (450 °F; 505 K)
Solubility in water Reacts to form TiO2
Solubility soluble in ethanol, ether, benzene, chloroform
Refractive index (nD) 1.46
Molecular Weight 284.22
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 0
Exact Mass 284.1467000
Monoisotopic Mass 284.1467000
Topological Polar Surface Area 92.2 Ų
Heavy Atom Count 17
Formal Charge 0
Complexity 10.8
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 5
Compound Is Canonicalized Yes
Molecular Formula C12H28O4Ti
Molar Mass 284.22
Density 0.96g/mLat 20°C(lit.)
Melting Point 14-17°C(lit.)
Boling Point 232°C(lit.)
Flash Point 72°F
Water Solubility HYDROLYSIS
Solubility Soluble in anhydrous ethanol, ether, benzene and chloroform.
Vapor Presure 60.2hPa at 25℃
Appearance Liquid
Specific Gravity 0.955
Color Colorless to pale yellow
Merck 14,9480
BRN 3679474
Storage Condition Flammables area
Stability Stable, but decomposes in the presence of moisture. Incompatible with aqueous solutions, strong acids, strong oxidizing agents. Flammable.
Sensitive 7: reacts slowly with moisture/water
Refractive Index n20/D 1.464(lit.)
Physical and Chemical Properties Character light yellow liquid, smoke in humid air.
boiling point 102~104 ℃
freezing point 14.8 ℃
relative density 0.954g/cm3
refractive index 1.46
soluble in a variety of organic solvents


SAFETY INFORMATION ABOUT TETRAISOPROPYL TITANATE:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

SYNONYMS OF TETRAISOPROPYL TITANATE:
titanium(IV) i-propoxide
isopropyl titanate
tetraisopropyl titanate
tetraisopropyl orthotitanate
titanium tetraisopropylate
orthotitanic acid tetraisopropyl ester
Isopropyl titanate(IV)
titanic acid tetraisopropyl ester
isopropyltitanate
titanium(IV) isopropoxide
titanium tetraisopropoxide
iso-propyl titanate
titanium tetraisopropanolate
tetraisopropoxytitanium(IV)
tetraisopropanolatotitanium
tetrakis(isopropoxy) titanium
tetrakis(isopropanolato) titanium
titanic acid isopropyl ester
titanic acid tetraisopropyl ester
titanium isopropoxide
titanium isopropylate
tetrakis(1-methylethoxy)titanium
Tetraisopropyl titanate
Titanium(IV) i-propoxide
Titanium tetraisopropoxide
Tetraisopropyl orthotitanate
tetraisopropyl titanate
Ti(IV) isopropoxide
Ti(OiPr)4
titanium isopropoxide
titanium tetraisopropoxide
titanium(IV) isopropoxide
Titanium tetraisopropanolate
546-68-9
Titanium(IV) isopropoxide
Titanium isopropoxide
Tetraisopropyl orthotitanate
Titanium tetraisopropoxide
Titanium isopropylate
Titanium tetraisopropylate
Tilcom TIPT
Ti Isopropylate
Tetraisopropoxytitanium(IV)
Isopropyl orthotitanate
Tetraisopropoxytitanium
Tetraisopropanolatotitanium
TETRAISOPROPYL TITANATE
A 1 (titanate)
Orgatix TA 10
Tetrakis(isopropoxy)titanium
Isopropyl titanate(IV)
Tyzor TPT
Isopropyl Titanate
propan-2-olate;titanium(4+)
TTIP
Tetraisopropoxide titanium
Titanium tetra-n-propoxide
Titanium(4+) isopropoxide
Titanic acid isopropyl ester
Titanium, tetrakis(1-methylethoxy)-
Titanium(IV) i-propoxide
Isopropyl alcohol, titanium(4+) salt
Titanium tetrakis(isopropoxide)
Isopropyl titanate(IV) ((C3H7O)4Ti)
titanium(IV)tetraisopropoxide
2-Propanol, titanium(4+) salt
titanium(IV) propan-2-olate
2-Propanol, titanium(4+) salt (4:1)
Titanium(IV) Tetraisopropoxide
Isopropyl alcohol titanium(4+) salt
76NX7K235Y
titanium tetra(isopropoxide)
MFCD00008871
tetrakis(propan-2-yloxy)titanium
Titanium isopropylate (VAN)
TITANIUM (IV) ISOPROPOXIDE
HSDB 848
Tetraksi(isopropanolato)titanium
NSC-60576
Isopropyl alcohol, titanium salt
Titanic acid tetraisopropyl ester
Titanium isopropoxide (Ti(OC3H7)4)
EINECS 208-909-6
Titanium isopropoxide (Ti(OCH7)4)
NSC 60576
Titanic(IV) acid, tetraisopropyl ester
C12H28O4Ti
UNII-76NX7K235Y
TIPT
Ti(OiPr)4
tetraisopropoxy titanium
tetraisopropoxy-titanium
titaniumtetraisopropoxide
titaniumtetraisopropylate
titanium(IV)isopropoxide
tetra-isopropoxy titanium
titanium (IV)isopropoxide
tetra-iso-propoxy titanium
titanium tetra-isopropoxide
titanium-tetra-isopropoxide
EC 208-909-6
titanium (4+) isopropoxide
VERTEC XL 110
tetraisopropoxytitanium (IV)
titanium tetra (isopropoxide)
titanium (IV)tetraisopropoxide
titanium (IV) tetraisopropoxide
TITANUM-(IV)-ISOPROPOXIDE
CHEBI:139496
AKOS015892702
TITANIUM TETRAISOPROPOXIDE [MI]
titanium(4+) tetrakis(propan-2-olate)
TITANIUM TETRAISOPROPANOLATE [HSDB]
T0133

Q2031021
208-909-6 [EINECS]
2-Propanol, titanium(4+) salt (4:1) [ACD/Index Name]
546-68-9 [RN]
MFCD00008871 [MDL number]
NT8060000
Propan-2-olate
Tétra(2-propanolate) de titane(4+) [French] [ACD/IUPAC Name]
Tetraisopropoxytitanium(IV)
Tetraisopropyl orthotitanate
Ti(OiPr)4 [Formula]
Titan(4+)tetra(2-propanolat) [German] [ACD/IUPAC Name]
titanium tetraisopropoxide
Titanium(4+) [ACD/Index Name] [ACD/IUPAC Name]
Titanium(4+) tetra(2-propanolate) [ACD/IUPAC Name]
Titanium(4+) tetrapropan-2-olate
Titanium(IV) isopropoxide
TTIP
115-08-2 [RN]
208-909-6MFCD00008871
76NX7K235Y
A 1 (titanate)
Isopropyl alcohol titanium(4+) salt
Isopropyl orthotitanate
Isopropyl titanate (IV)
Isopropyl titanate(IV) ((C3H7O)4Ti)
Orgatix TA 10
Tetraisopropanolatotitanium
Tetraisopropoxide titanium
tetraisopropoxytitanium
tetra-iso-Propyl orthotitanate
tetraisopropyl titanate
tetra-iso-Propyl titanate
Tetrakis(isopropoxy)titanium
TETRAKIS(ISOPROPYLOXY)TITANIUM
tetrakis(propan-2-yloxy)titanium
Ti Isopropylate
Titan(4+)tetrapropan-2-olat
Titanic acid isopropyl ester
Titanium isopropoxide
Titanium isopropoxide (Ti(OC3H7)4)
Titanium Isopropylate
Titanium tetraisopropanolate
Titanium tetraisopropylate
Titanium tetrakis(isopropoxide)
Titanium tetra-n-propoxide
Titanium(4+) isopropoxide
TITANIUM(4+) TETRAKIS(PROPAN-2-OLATE)
Titanium(IV) i-propoxide
titanium(IV) propan-2-olate
Titanium, tetrakis(1-methylethoxy)-
Titanium, tetrakis(isopropoxy)-
TYZOR organic titanate
Tyzor TPt

Tetraisopropyl titanate, often abbreviated as TIPT, is a chemical compound with the molecular formula C12H28O4Ti.
Tetraisopropyl titanate (TIPT) belongs to the class of organotitanium compounds and is characterized by the presence of four isopropyl groups bonded to a titanium atom.

CAS Number: 546-68-9
EC Number: 208-909-6

Synonyms: Tetraisopropyl titanate, TIPT, Tetraisopropanolate titan, Tetraisopropoxytitanium, Tetraisopropyl orthotitanate, Tetraisopropyltitanium, Titanium tetraisopropoxide, Tetrakis(isopropoxy)titanium,Isopropyl titanate, Tetraisopropyltitanoxide, Tetrakis(isopropyl)titanium



APPLICATIONS


Tetraisopropyl titanate (TIPT) is widely used as a catalyst in the synthesis of polyolefins such as polyethylene and polypropylene.
Tetraisopropyl titanate (TIPT) serves as a precursor in the production of titanium-containing catalysts for olefin polymerization reactions.
Tetraisopropyl titanate (TIPT) is utilized in the manufacture of silicone rubbers and resins as a cross-linking agent to improve mechanical properties.

Tetraisopropyl titanate (TIPT) acts as an adhesion promoter in coatings and adhesives, enhancing the bonding between substrates and the applied materials.
In the textile industry, Tetraisopropyl titanate is employed as a water repellent agent for fabrics.

Tetraisopropyl titanate (TIPT) finds application in the production of ceramics as a sintering aid to improve the density and strength of ceramic materials.
Tetraisopropyl titanate (TIPT) is used in surface treatments to modify the properties of materials such as metals and glass, enhancing durability and corrosion resistance.
Tetraisopropyl titanate (TIPT) is a key ingredient in the formulation of fuel additives to improve combustion efficiency and reduce emissions.

Tetraisopropyl titanate is utilized in the electronics industry for the production of dielectric films and coatings.
Tetraisopropyl titanate (TIPT) is employed in the synthesis of hybrid organic-inorganic materials with tailored properties for various industrial applications.
Tetraisopropyl titanate (TIPT) plays a role in the formulation of specialty paints and coatings to enhance weather resistance and durability.

In adhesive formulations, it helps to improve the adhesion strength between substrates and the adhesive material.
Tetraisopropyl titanate (TIPT) is used in the production of photovoltaic (solar cell) materials and coatings to enhance efficiency and stability.
Tetraisopropyl titanate (TIPT) serves as a catalyst and promoter in the synthesis of organic esters and other organic compounds.

Tetraisopropyl titanate (TIPT) is applied in the production of antifouling coatings for marine applications to prevent biofouling.
Tetraisopropyl titanate (TIPT) finds use in the automotive industry for coatings and treatments that improve scratch resistance and appearance.

Tetraisopropyl titanate (TIPT) is utilized in the formulation of inkjet printing inks for improved adhesion and print quality.
Tetraisopropyl titanate (TIPT) is employed in the synthesis of titanium dioxide nanoparticles for use in cosmetics and sunscreen formulations.

Tetraisopropyl titanate (TIPT) is used in the preparation of corrosion-resistant coatings for metal surfaces in industrial and marine environments.
In the construction industry, it is used as a water repellent agent for concrete and masonry surfaces.

Tetraisopropyl titanate is employed in the production of high-performance lubricants and greases.
Tetraisopropyl titanate (TIPT) finds application in the aerospace industry for coatings and treatments that enhance resistance to high temperatures and corrosion.

Tetraisopropyl titanate (TIPT) is used in the formulation of specialty polymers and resins with improved mechanical and thermal properties.
Tetraisopropyl titanate (TIPT) plays a role in the synthesis of nanoparticles and nanocomposites for advanced materials and biomedical applications.
Tetraisopropyl titanate (TIPT) is utilized in research and development for its role in the synthesis of novel materials with tailored properties for specific industrial and scientific applications.

Tetraisopropyl titanate is extensively used as a catalyst in the polymerization of olefins such as polyethylene and polypropylene.
Tetraisopropyl titanate (TIPT) serves as a precursor in the synthesis of titanium-based catalysts employed in the production of plastics and elastomers.

Tetraisopropyl titanate (TIPT) is utilized in the formulation of silicone rubbers and resins as a cross-linking agent to improve mechanical properties.
Tetraisopropyl titanate (TIPT) acts as an adhesion promoter in coatings and adhesives, enhancing bonding to substrates like metals and glass.
In the textile industry, Tetraisopropyl titanate functions as a water repellent agent for fabrics and textiles.

Tetraisopropyl titanate (TIPT) is employed in the ceramics industry as a sintering aid to enhance the strength and density of ceramic materials.
Tetraisopropyl titanate (TIPT) finds application in surface treatments to modify the properties of materials, improving durability and corrosion resistance.
In fuel additives, Tetraisopropyl titanate enhances combustion efficiency and reduces emissions in automotive and industrial applications.

Tetraisopropyl titanate (TIPT) is used in electronics for the production of dielectric films and coatings, contributing to the performance of electronic devices.
Tetraisopropyl titanate (TIPT) is utilized in the synthesis of hybrid organic-inorganic materials with tailored properties for various industrial applications.

In the automotive sector, Tetraisopropyl titanate is employed in coatings and treatments to enhance scratch resistance and appearance.
Tetraisopropyl titanate (TIPT) finds application in photovoltaic materials and coatings to improve the efficiency and stability of solar cells.

Tetraisopropyl titanate (TIPT) plays a role in adhesive formulations, improving adhesion strength and durability in bonding applications.
Tetraisopropyl titanate (TIPT) is used in the production of specialty paints and coatings for enhanced weather resistance and longevity.

In the aerospace industry, Tetraisopropyl titanate is utilized in coatings that resist high temperatures and corrosion.
Tetraisopropyl titanate (TIPT) is applied in inkjet printing inks to enhance adhesion and print quality on various substrates.
Tetraisopropyl titanate (TIPT) contributes to the synthesis of titanium dioxide nanoparticles used in cosmetics, sunscreens, and photocatalysts.

As a corrosion-resistant coating agent, Tetraisopropyl titanate protects metal surfaces in harsh industrial and marine environments.
Tetraisopropyl titanate (TIPT) is used in construction for water repellent treatments on concrete and masonry surfaces.
Tetraisopropyl titanate (TIPT) finds application in the formulation of high-performance lubricants and greases.

Tetraisopropyl titanate (TIPT) is utilized in the production of antifouling coatings to prevent marine biofouling on ship hulls and underwater structures.
Tetraisopropyl titanate (TIPT) plays a role in the formulation of sealants and caulks, improving their adhesion and durability.
Tetraisopropyl titanate (TIPT) is used in the manufacturing of fiberglass reinforced plastics (FRP) to enhance resin curing and composite strength.

Tetraisopropyl titanate (TIPT) finds application in the synthesis of organotitanium compounds used as coupling agents in polymer composites.
Tetraisopropyl titanate (TIPT) is valued for its versatility and ability to enhance material properties across a wide range of industries, from chemicals and coatings to electronics and renewable energy sectors.

Tetraisopropyl titanate (TIPT) is utilized in the formulation of corrosion inhibitors for protecting metal surfaces against rust and degradation.
Tetraisopropyl titanate (TIPT) plays a role in the production of advanced ceramics used in electronic components, aerospace applications, and medical devices.

Tetraisopropyl titanate is used in the formulation of release agents and mold treatments in the plastics and rubber industries.
Tetraisopropyl titanate (TIPT) finds application as a processing aid in the production of thermoplastic elastomers (TPE) and thermosetting resins.

Tetraisopropyl titanate (TIPT) is employed in the synthesis of titanium-containing nanoparticles for biomedical applications such as drug delivery systems.
Tetraisopropyl titanate (TIPT) contributes to the development of high-performance coatings for architectural applications, enhancing building aesthetics and durability.
In the semiconductor industry, Tetraisopropyl titanate is used in the deposition of thin films for integrated circuits and microelectronics.

Tetraisopropyl titanate (TIPT) is applied in the manufacturing of optical coatings to improve light transmission and anti-reflective properties.
Tetraisopropyl titanate (TIPT) is used in the formulation of heat-resistant paints and coatings for industrial equipment and machinery.

Tetraisopropyl titanate (TIPT) plays a role in the production of catalysts used in the purification of industrial gases and wastewater treatment processes.
Tetraisopropyl titanate is employed in the synthesis of titanium-containing polymers with enhanced thermal and mechanical properties.
Tetraisopropyl titanate (TIPT) finds application in the formulation of anti-corrosion coatings for offshore platforms and marine structures.

Tetraisopropyl titanate (TIPT) is utilized in the production of specialty adhesives for bonding composites, plastics, and metals in aerospace and automotive applications.
Tetraisopropyl titanate (TIPT) contributes to the development of conductive coatings and inks used in electronic circuitry and printed electronics.
In the pharmaceutical industry, Tetraisopropyl titanate is used in the formulation of controlled-release drug delivery systems.

Tetraisopropyl titanate (TIPT) finds application in the production of ceramic capacitors and piezoelectric devices used in electronics and telecommunications.
Tetraisopropyl titanate (TIPT) is employed in the synthesis of titanium-based additives for improving the performance of lubricants and greases.

Tetraisopropyl titanate (TIPT) plays a role in the formulation of protective coatings for glass and optical lenses, enhancing scratch resistance and clarity.
Tetraisopropyl titanate is used in the production of composite materials for lightweight and high-strength applications in aerospace and automotive sectors.
Tetraisopropyl titanate (TIPT) is applied in the formulation of coatings for solar panels to enhance weather resistance and efficiency.

Tetraisopropyl titanate (TIPT) finds application in the production of heat-resistant fibers and textiles used in protective clothing and industrial applications.
Tetraisopropyl titanate (TIPT) is utilized in the formulation of sealants and caulks for construction applications, improving adhesion and durability.
Tetraisopropyl titanate is used in the synthesis of titanium-based pigments and dyes for paints, inks, and plastics.

Tetraisopropyl titanate (TIPT) contributes to the formulation of water treatment chemicals and additives for improving water quality and filtration processes.
Tetraisopropyl titanate (TIPT) continues to find diverse applications across industries, driving innovation in materials science, coatings technology, electronics, and environmental protection.
Tetraisopropyl titanate (TIPT) is used in electronics for dielectric films and coatings, contributing to the performance and reliability of electronic devices.
Tetraisopropyl titanate (TIPT) is employed in the synthesis of hybrid organic-inorganic materials with tailored properties for diverse industrial applications.
In the automotive sector, Tetraisopropyl titanate is used in coatings and treatments to improve scratch resistance and appearance.

Tetraisopropyl titanate (TIPT) finds application in photovoltaic materials and coatings, contributing to the efficiency and stability of solar cells.
Tetraisopropyl titanate (TIPT) plays a crucial role in adhesive formulations, improving the adhesion strength and durability of bonded materials.

Tetraisopropyl titanate (TIPT) is utilized in the production of specialty paints and coatings for enhanced weather resistance and longevity.
In the aerospace industry, Tetraisopropyl titanate is used in coatings and treatments that resist high temperatures and corrosion.

Tetraisopropyl titanate (TIPT) is employed in inkjet printing inks to improve adhesion and print quality on various substrates.
Tetraisopropyl titanate (TIPT) plays a role in the synthesis of titanium dioxide nanoparticles for use in cosmetics, sunscreens, and photocatalysts.
As a corrosion-resistant coating agent, Tetraisopropyl titanate protects metal surfaces in harsh industrial and marine environments.

Tetraisopropyl titanate (TIPT) is used in construction for water repellent treatments on concrete and masonry surfaces.
Tetraisopropyl titanate (TIPT) finds application in the formulation of high-performance lubricants and greases.
Tetraisopropyl titanate (TIPT) is valued for its versatility and role in enhancing materials' properties across multiple industries, from chemicals and coatings to electronics and renewable energy sectors.



DESCRIPTION


Tetraisopropyl titanate, often abbreviated as TIPT, is a chemical compound with the molecular formula C12H28O4Ti.
Tetraisopropyl titanate (TIPT) belongs to the class of organotitanium compounds and is characterized by the presence of four isopropyl groups bonded to a titanium atom.

Tetraisopropyl titanate, often abbreviated as TIPT, is a colorless to pale yellow liquid with a mild odor.
Tetraisopropyl titanate (TIPT) has a molecular formula of C12H28O4Ti and a molecular weight of approximately 284.22 g/mol.
Tetraisopropyl titanate (TIPT) is characterized by its tetrahedral structure, where a titanium atom is bonded to four isopropyl groups (-CH(CH3)2).

Tetraisopropyl titanate (TIPT) is highly reactive due to the presence of the titanium-oxygen bonds, which undergo hydrolysis and oxidation reactions.
Tetraisopropyl titanate (TIPT) is soluble in organic solvents such as alcohols, ethers, and hydrocarbons but practically insoluble in water.
Tetraisopropyl titanate (TIPT) is known for its role as a catalyst and precursor in the synthesis of titanium-containing catalysts used in polymerization reactions.

Tetraisopropyl titanate (TIPT) serves as a cross-linking agent in the production of silicone rubbers and resins, enhancing their mechanical properties.
As an adhesion promoter, Tetraisopropyl titanate improves the bonding strength between coatings, adhesives, and various substrates.

In textile applications, TIPT acts as a water repellent agent, imparting hydrophobic properties to fabrics.
Tetraisopropyl titanate (TIPT) is utilized in the ceramics industry as a sintering aid to improve the density and strength of ceramic materials.

Tetraisopropyl titanate (TIPT) finds application in surface treatments to modify the properties of metals and glass, enhancing their durability and corrosion resistance.
In fuel additives, Tetraisopropyl titanate enhances combustion efficiency and reduces emissions in combustion processes.



PROPERTIES


Physical Properties:

Appearance: Clear to pale yellow liquid
Odor: Mild odor
Molecular Weight: Approximately 284.22 g/mol
Density: ~0.99 g/cm³
Melting Point: Not applicable (liquid at room temperature)
Boiling Point: 242-245°C (467-473°F)
Flash Point: 100°C (212°F) (closed cup)
Solubility in Water: Practically insoluble
Solubility in Other Solvents: Soluble in organic solvents such as alcohols, ethers, and hydrocarbons
Vapor Pressure: Low, typical for organic liquids
Viscosity: Low viscosity liquid


Chemical Properties:

Chemical Formula: C12H28O4Ti
Structure: Tetrahedral structure with a titanium atom bonded to four isopropyl groups (-CH(CH3)2)
Reactivity: Highly reactive due to titanium-oxygen bonds, undergoes hydrolysis and oxidation reactions
Hydrolysis: Reacts readily with water to form titanic acid and isopropanol
Purity: Commercial grades typically ≥ 97% purity
Storage Stability: Stable under recommended storage conditions
Flammability: Flammable liquid, handle with care
Corrosivity: Non-corrosive to metals under normal conditions
Acidity/Basicity: Neutral pH in solution
Compatibility: Compatible with most organic solvents but incompatible with strong acids and bases
Catalytic Activity: Acts as a catalyst or catalyst precursor in various chemical reactions
Redox Properties: Participates in redox reactions involving titanium oxidation states



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
If breathing is difficult, provide oxygen if available.
Seek medical attention.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash skin with plenty of soap and water for at least 15 minutes.
If irritation develops or persists, seek medical advice.


Eye Contact:

Immediately flush eyes with gently flowing water for at least 15 minutes, lifting upper and lower eyelids occasionally.
Seek immediate medical attention, preferably from an eye specialist.


Ingestion:

Rinse mouth thoroughly and drink plenty of water.
Do not induce vomiting unless instructed by medical personnel.
Seek immediate medical attention or contact a poison control center.


General Advice:

Exposure Controls:
Ensure adequate ventilation in the work area to minimize exposure to vapors. Use local exhaust ventilation if necessary.

Personal Protective Equipment:
Wear chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact.

Handling:
Avoid breathing vapors or mist.
Handle TIPT in a well-ventilated area or use respiratory protection if ventilation is inadequate.

Storage:
Store TIPT in tightly sealed containers away from heat, sparks, and open flames. Store in a cool, dry place away from incompatible materials.

Spill Cleanup:
Contain spills with absorbent materials and collect in suitable containers for disposal according to local regulations.

Firefighting:
Use foam, carbon dioxide, dry chemical, or water fog for firefighting.
Avoid direct water streams, as they may spread the fire.

Medical Attention:
Provide this Safety Data Sheet to medical personnel treating anyone exposed to TIPT.



HANDLING AND STORAGE


Handling:

Ventilation:
Use TIPT in a well-ventilated area to prevent the buildup of vapors.
Ensure adequate general and local exhaust ventilation systems.
If handling in confined spaces, use respiratory protection (e.g., NIOSH-approved respirator) to prevent inhalation of vapors.

Personal Protective Equipment (PPE):
Wear chemical-resistant gloves (e.g., nitrile or neoprene), safety goggles or face shield, and protective clothing (e.g., long-sleeved shirt and pants) to prevent skin contact.
Use impervious aprons or coveralls if there is a risk of splashing or contamination.

Avoid Contact:
Avoid skin and eye contact with TIPT. In case of accidental contact, follow the first aid measures outlined in the Safety Data Sheet (SDS).
Wash hands and any exposed skin thoroughly after handling TIPT, even if gloves are worn.

Handling Precautions:
Handle TIPT with care to prevent spills and splashes.
Use appropriate handling equipment and containers designed for chemical storage.
Do not eat, drink, or smoke while handling TIPT.
Avoid inhalation of vapors or mist.

Static Electricity:
Take precautions to prevent static electricity buildup, which can result in ignition of TIPT vapors.
Ground all equipment and containers during transfer and handling.

Equipment Cleaning:
Clean equipment and tools thoroughly after use with TIPT. Dispose of contaminated materials according to local regulations.


Storage:

Storage Conditions:
Store Tetraisopropyl titanate in tightly closed containers made of suitable materials such as stainless steel or high-density polyethylene (HDPE).
Store in a cool, dry, well-ventilated area away from direct sunlight, heat sources, sparks, and open flames.
Maintain storage temperature between 15°C to 25°C (59°F to 77°F) to ensure stability and reduce the risk of decomposition.

Incompatible Materials:
Store TIPT away from strong acids, bases, oxidizers, and incompatible materials to prevent hazardous reactions or degradation.
Keep containers tightly sealed when not in use to prevent contamination and minimize exposure to moisture.

Handling Large Quantities:
If handling large quantities of TIPT, consider storing in a dedicated chemical storage area with appropriate containment measures in case of spills or leaks.
Ensure storage area is equipped with spill containment materials and cleanup supplies.

Labeling and Identification:
Clearly label containers with the product name, chemical formula, hazard symbols, and safety precautions.
Keep Safety Data Sheets (SDS) readily available for reference by personnel handling or storing TIPT.

Emergency Response Preparation:
Have emergency response procedures in place, including spill containment and cleanup protocols, as well as procedures for fire and medical emergencies.
Train personnel in safe handling practices and emergency response procedures related to Tetraisopropyl titanate.

Disposal:
Dispose of Tetraisopropyl titanate and contaminated materials in accordance with local, state, and federal regulations.
Contact a licensed waste disposal company or local environmental authorities for guidance on proper disposal methods and facilities.

Tetraisopropyl titanate (TIPT) is a colourless, slightly yellowish liquid that is very sensitive to moisture.
Tetraisopropyl titanate (TIPT) is a colourless to light yellow liquid.


CAS Number: 546-68-9
EC number: 208-909-6
MDL number: MFCD00008871
Molecular Formula: C12H28O4Ti



SYNONYMS:
Titanium isopropoxide, Titanium isopropylate, 2-Propanol, titanium(4+) salt, Isopropyl alcohol titanium(4+) salt, Isopropyl alcohol, titanium salt, Isopropyl orthotitanate, Isopropyl titanate(IV), Isopropyl titanate(IV) ((C3H7O)4Ti), Orgatix TA 10, Tetraisopropanolatotitanium, Tetraisopropoxide titanium, Tetraisopropoxytitanium, Tetraisopropoxytitanium(IV), Tetraisopropyl orthotitanate, Tetrakis(isopropoxy)titanium, Tetraksi(isopropanolato)titanium, Ti Isopropylate, Tilcom TIPT, Titanic acid isopropyl ester, Titanic acid tetraisopropyl ester, Titanic(IV) acid, tetraisopropyl ester, Titanium isopropoxide (Ti(OCH7)4), Titanium isopropylate, Titanium isopropylate (VAN), Titanium tetra-n-propoxide, Titanium tetraisopropoxide, Titanium tetraisopropylate, Titanium tetrakis(isopropoxide), Titanium(4+) isopropoxide, Titanium(IV) isopropoxide, Titanium, tetrakis(1-methylethoxy)-, Tetra isoprobyl titanate (TIPT), Titanium(IV) isopropoxide, Tetraisopropyl titanate, Titanium(IV) i-propoxide, Titanium tetraisopropoxide, Tetraisopropyl orthotitanate, TITANIUM ISOPROPOXIDE,TITANIUM(IV) ISOPROPOXIDE,TITANIUM TETRAISOPROPOXIDE,TTIP,tetraisopropoxytitanium,TETRAISOPROPYL TITANATE,ISOPROPYL TITANATE,Titanium(Ⅳ) isopropoxide,TETRAISOPROPYL ORTHOTITANATE,TITANIUM(IV) TETRAISOPROPOXIDE, 2-Propanol, titanium(4+) salt, A 1 (titanate), Isopropyl alcohol titanium(4+) salt, Isopropyl alcohol, titanium salt, Isopropyl orthotitanate, Isopropyl titanate(IV), Isopropyl titanate(IV) ((C3H7O)4Ti), Orgatix TA 10, TA 10, Tetraisopropanolatotitanium, Tetraisopropoxide titanium, Tetraisopropoxytitanium, Tetraisopropoxytitanium(IV), Tetraisopropyl orthotitanate, Tetrakis(isopropoxy)titanium, Tetrakis(isopropanolato)titanium, Ti Isopropylate, Tilcom TIPT, Titanic acid isopropyl ester, Titanic acid tetraisopropyl ester, Titanic(IV) acid, tetraisopropyl ester, Titanium isopropoxide (Ti(OC3H7)4), Titanium isopropylate, Titanium isopropylate (VAN), Titanium tetraisopropoxide, Titanium tetraisopropylate, Titanium tetrakis(isopropoxide), Titanium(4+) isopropoxide, Titanium(IV) isopropoxide, Titanium, tetrakis(1-methylethoxy)-, Tyzor TPT, [ChemIDplus] UN2413, Titanium (IV) isopropoxide, Tetraisopropyl Orthotitanate, Isopropyl Titanate, 2-Propanol, titanium(4+) salt, Tetraisopropyl titanate, Titanium tetraisopropoxide, Tetraisopropoxy titanium, ISOPROPYL TITANATE, ISOPROPYL TITANATE(IV), TITANIUM ISOPROPOXIDE, TITANIUM ISO-PROPYLATE, TITANIUM (IV) I-PROPOXIDE, TITANIUM(IV) ISOPROPOXIDE, TITANIUM (IV) TETRA-I-PROPOXIDE, TITANIUM(IV) TETRAISOPROPOXIDE, Isopropyl orthotitanate, Isopropyl titanate(IV) ((C3H7O)4Ti), Tetraisopropanolatotitanium, Tetraisopropoxytitanium, Tetraisopropoxytitanium(IV), Tetraisopropyl orthotitanate, Tetraisopropyl titanate, Tetrakis(isopropanolato)titanium, Tetrakis(isopropoxide)titanium, Tetrakis(isopropoxy)titanium, Tetrakis(isopropylato)titanium(IV), Tetrakis(isopropyloxy)titanium, TIPT, Titanium isopropoxide, Titanium isopropylate, Titanium tetraisopropoxide, Titanium tetraisopropylate, Titanium tetrakis(iso-propoxide), Titanium tetrakis(isopropoxide), Titanium(4+) isopropoxide, Titanium(IV) isopropoxide, TETRAISOPROPYL TITANATE (FLAMMABLE LIQUIDS, N.O.S.), A 1, A 1 (TITANATE), ISOPROPYL ALCOHOL, TITANIUM(4+) SALT, ISOPROPYL ORTHOTITANATE, ISOPROPYL TITANATE(IV) ((C3H7O)4TI), ORGATIX TA 10, TETRAISOPROPANOLATOTITANIUM, TETRAISOPROPOXYTITANIUM, TETRAISOPROPYL ORTHOTITANATE, TETRAISOPROPYL TITANATE, TETRAKIS(ISOPROPOXY)TITANIUM, TETRAKIS(ISOPROPYLATO)TITANIUM(IV), TETRAKIS(ISOPROPYLOXY)TITANIUM, TILCOM TIPT, TITANIUM ISOPROPOXIDE, TITANIUM ISOPROPOXIDE (TI(OC3H7)4), TITANIUM ISOPROPYLATE, TITANIUM TETRAISOPROPOXIDE, TITANIUM TETRAISOPROPYLATE, TITANIUM TETRAKIS(ISO-PROPOXIDE), TITANIUM TETRAKIS(ISOPROPOXIDE), TITANIUM(4+) ISOPROPOXIDE, TITANIUM(IV) ISOPROPOXIDE, TITANIUM, TETRAKIS(1-METHYLETHOXY)-, TPT, TYZOR TPT, Titanium tetraisopropanolate, 546-68-9, Titanium isopropoxide, Titanium isopropylate, Titanium tetraisopropylate, Tetraisopropyl orthotitanate, Tilcom TIPT, Titanium tetraisopropoxide, Ti Isopropylate, Tetraisopropoxytitanium(IV), Isopropyl orthotitanate, Tetraisopropoxytitanium, Tetraisopropanolatotitanium, TETRAISOPROPYL TITANATE, propan-2-olate; titanium(4+), A 1 (titanate), Orgatix TA 10, Tetrakis(isopropoxy)titanium, Tyzor TPT, Isopropyl Titanate, TTIP, Tetraisopropoxide titanium, Titanium tetra-n-propoxide, Titanium(4+) isopropoxide, Titanic acid isopropyl ester, Titanium, tetrakis(1-methylethoxy)-, Isopropyl alcohol, titanium(4+) salt, Titanium tetrakis(isopropoxide), Isopropyl titanate(IV) ((C3H7O)4Ti), 2-Propanol, titanium(4+) salt, titanium(IV) propan-2-olate, 2-Propanol, titanium(4+) salt (4:1), Titanium(IV) Tetraisopropoxide, Isopropyl alcohol titanium(4+) salt, 76NX7K235Y, titanium(4+) tetrakis(propan-2-olate), Isopropyl titanate(IV), titanium tetra(isopropoxide), Titanium isopropylate (VAN), TITANIUM (IV) ISOPROPOXIDE, titanium(4+) tetrapropan-2-olate, HSDB 848, Tetraksi(isopropanolato)titanium, NSC-60576, Isopropyl alcohol, titanium salt, Titanic acid tetraisopropyl ester, Titanium isopropoxide (Ti(OC3H7)4), EINECS 208-909-6, Titanium isopropoxide (Ti(OCH7)4), NSC 60576, Titanic(IV) acid, tetraisopropyl ester, titanium(IV)tetraisopropoxide, C12H28O4Ti, UNII-76NX7K235Y, TIPT, Ti(OiPr)4, tetraisopropoxy titanium, tetraisopropoxy-titanium, titaniumtetraisopropoxide, titaniumtetraisopropylate, titanium(IV)isopropoxide, tetra-isopropoxy titanium, titanium (IV)isopropoxide, tetra-iso-propoxy titanium, titanium tetra-isopropoxide, titanium-tetra-isopropoxide, EC 208-909-6, titanium (4+) isopropoxide, Titanium isopropoxide(TTIP), VERTEC XL 110, tetraisopropoxytitanium (IV), titanium tetra (isopropoxide), titanium(IV)tetraisopropoxide, titanium(IV) tetraisopropoxide, TITANUM-(IV)-ISOPROPOXIDE, CHEBI:139496, AKOS015892702, TITANIUM TETRAISOPROPOXIDE [MI], TITANIUM TETRAISOPROPANOLATE [HSDB], T0133, Q2031021, 2923581-56-8



Tetraisopropyl titanate (TIPT) is a colourless to light yellow liquid.
Tetraisopropyl titanate (TIPT) is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.
Tetraisopropyl titanate (TIPT) appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol.


Tetraisopropyl titanate (TIPT) appears as a colorless to pale yellow liquid with a mild odor.
Tetraisopropyl titanate (TIPT), with the chemical formula C12H28O4Ti, has the CAS number 546-68-9.
Tetraisopropyl titanate (TIPT) is a titanium alkoxide.


Tetraisopropyl titanate (TIPT) is a highly reactive catalyst & can be used in direct & transesterification reactions.
Tetraisopropyl titanate (TIPT) is a titanium alkoxide.
Tetraisopropyl titanate (TIPT), also commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4.


Tetraisopropyl titanate (TIPT) is a diamagnetic tetrahedral molecule.
Tetraisopropyl titanate (TIPT) is a chemical compound with the formula Ti(OCH(CH)) (i-Pr).
Tetraisopropyl titanate (TIPT) is an organotitanium compound that reacts with water to form titanium hydroxide.


Tetraisopropyl titanate (TIPT), also commonly referred to as titanium tetraisopropoxide or TTIP, is a chemical compound with the formula Ti{OCH(CH3)2}4.
This alkoxide of titanium(IV) is used in organic synthesis and materials science.
Tetraisopropyl titanate (TIPT) is a diamagnetic tetrahedral molecule.


Tetraisopropyl titanate (TIPT) is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.
Tetraisopropyl titanate (TIPT), with the chemical formula C12H28O4Ti, has the CAS number 546-68-9.
Tetraisopropyl titanate (TIPT) appears as a colorless to pale yellow liquid with a mild odor.


The basic structure of Tetraisopropyl titanate (TIPT) consists of four isopropanol groups attached to a central titanium atom.
Tetraisopropyl titanate (TIPT) is soluble in organic solvents such as ethanol and acetone, but insoluble in water.
Tetraisopropyl titanate (TIPT) is important to handle this chemical with caution and use appropriate protective measures to avoid any potential harm.


Tetraisopropyl titanate (TIPT) is a highly reactive catalyst & can be used in direct & transesterification reactions.
Tetraisopropyl titanate (TIPT) is a type of very lively primary alcohol titanium oxide; it hydrolyzes when contacted with moisture in air.
Tetraisopropyl titanate (TIPT) belongs to the product group of organic titanates, which are known to be highly reactive organics that can be used in a broad range of processes and applications.


The structures of the titanium alkoxides are often complex.
Crystalline titanium methoxide is tetrameric with the molecular formula C12H28O4Ti.
Tetraisopropyl titanate (TIPT) has a low vapor pressure and a high melting point, which makes it well suited for use in high temperature environments.


Tetraisopropyl titanate (TIPT) is a colorless to slightly yellow liquid that is typically stored under an inert atmosphere, such as nitrogen or argon, to prevent degradation.
Moreover, Tetraisopropyl titanate (TIPT) is often supplied in amber glass or metal containers, which protect against chemical and photochemical degradation.


Tetraisopropyl titanate (TIPT) is a colourless, slightly yellowish liquid that is very sensitive to moisture.
Typical users in plasticizer, acrylate and methacrylate manufacturers.
Tetraisopropyl titanate (TIPT) appears as a water-white to pale-yellow liquid with an odor like isopropyl alcohol.


Tetraisopropyl titanate (TIPT) is a diamagnetic tetrahedral molecule.
Alkoxides derived from bulkier alcohols such as isopropyl alcohol aggregate less.
Tetraisopropyl titanate (TIPT) is mainly a monomer in nonpolar solvents.


The primary method of synthesis involves the reaction of titanium tetrachloride with isopropanol.
This reaction is exothermic and produces corrosive coproducts such as hydrogen chloride and must be controlled carefully to prevent overheating and associated ignition and corrosion risks.


Through continuous research and innovation, methods are continually being refined to enhance the efficiency, increase yield, eliminate unwanted byproducts and safety of these processes by reduction of toxicity when used to replace traditional catalysts.
Tetraisopropyl titanate (TIPT) is colorless to light yellow transparent liquid.


Isopropyl titanate, also known as Tetraisopropyl titanate (TIPT), titanium tetraisopropoxide is the isopropoxide of titanium (IV), used in organic synthesis and materials science.
Tetraisopropyl titanate (TIPT) is a precursor for the preparation of Titania.


Tetraisopropyl titanate (TIPT) is a titanium coordination entity consisting of a titanium(IV) cation with four propan-2-olate anions as counterions.
Tetraisopropyl titanate (TIPT) is an alkoxy titanate with a high level of reactivity.
Tetraisopropyl titanate (TIPT) belongs to organic titanates group.


Special handling equipment is necessary to exclude any contact with air or moisture causing premature hydrolysis of the compound.
Ultimately, the production and use of Tetraisopropyl titanate (TIPT) is a complex process that demands a high degree of precision, safety, and quality control.


Tetraisopropyl titanate (TIPT) is mainly a monomer in nonpolar solvents.
Tetraisopropyl titanate (TIPT) has a complex structure.
Tetraisopropyl titanate (TIPT) is a chemical compound with the formula Ti{OCH(CH3)2}4.


The structures of the titanium alkoxides are often complex.
Crystalline titanium methoxide is tetrameric with the molecular formula Ti4(OCH3)16.
Alkoxides derived from bulkier alcohols such isopropanol aggregate less.


Tetraisopropyl titanate (TIPT) is mainly a monomer in nonpolar solvents.
Tetraisopropyl titanate (TIPT) is water rapid hydrolysis, soluble in alcohol, ether, ketone, benzene and other organic solvents.
Tetraisopropyl titanate (TIPT) has a complex structure.


In crystalline state, Tetraisopropyl titanate (TIPT) is a tetramer.
Non-polymerized in non-polar solvents, Tetraisopropyl titanate (TIPT) is a tetrahedral diamagnetic molecule.
Isopropyl titanate, also known as Tetraisopropyl titanate (TIPT), titanium tetraisopropoxide is the isopropoxide of titanium (IV), used in organic synthesis and materials science.


Tetraisopropyl titanate (TIPT) has a complex structure.
In crystalline state, Tetraisopropyl titanate (TIPT) is a tetramer.
Non-polymerized in non-polar solvents, it is a tetrahedral diamagnetic molecule.


Tetraisopropyl titanate (TIPT) is a highly reactive organic widely used in different applications as well as processes.
This slighty yellow to colorless liquid, Tetraisopropyl titanate (TIPT) is highly-sensitive to moisture.
Tetraisopropyl titanate (TIPT) is an organic titanate that has a wide range of applications across several industries.


Tetraisopropyl titanate (TIPT) belongs to the product group of organic titanates, which are known to be highly reactive organics that can be used in a broad range of processes and applications.
Tetraisopropyl titanate (TIPT) is a colorless, slighty yellowish liquid that is very sensitive to moisture.
Tetraisopropyl titanate (TIPT) is an organic compound composed of titanium and isopropyl groups (-C(CH3)2).



USES and APPLICATIONS of TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) can be used directly or in directly as a catalyst or catlyst additive,as a coating primer or added to formulation as a adhesion promoter and as the base material in the formation fo sol-get systems or nanoparticle systems or products.
Tetraisopropyl titanate (TIPT) can be used as sharpless oxidation catalyst.


Tetraisopropyl titanate (TIPT) is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is used as an auxiliary agent and chemical product intermediate.
Tetraisopropyl titanate (TIPT) is used to make adhesives, as a catalyst for transesterification and polymerization reactions.


Binders for preparing metals and rubber, metals and plastics, Tetraisopropyl titanate (TIPT) is also used as catalysts for transesterification and polymerization reactions and raw materials for the pharmaceutical industry.
Tetraisopropyl titanate (TIPT) is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes.


Tetraisopropyl titanate (TIPT) is used for ester exchange reaction
Tetraisopropyl titanate (TIPT) is used as additive and intermediate of chemical products
Tetraisopropyl titanate (TIPT) is used for making adhesives, as catalysts for transesterification reaction and polymerization reaction


Tetraisopropyl titanate (TIPT) is used synthesize all kinds of titanate coupling agent, cross-linking agent and dispersant.
Tetraisopropyl titanate (TIPT) is a type of very lively primary titanium oxide; it hydrolyzes when contacted with moisture in air.
Tetraisopropyl titanate (TIPT) is mainly used as catalyst in esterification reaction or transesterification, also being used as catalyst of polyolefin.


Tetraisopropyl titanate (TIPT) is an active component of sharpless epoxidation as well as involved in the synthesis of chiral epoxides.
In Kulinkovich reaction, Tetraisopropyl titanate (TIPT) is involved as a catalyst in the preparation of cyclopropanes.
Tetraisopropyl titanate (TIPT) can also be used as raw materials for the pharmaceutical industry and the preparation of metal and rubber, metal and plastic adhesives.


Tetraisopropyl titanate (TIPT) can also be used as surface modifier, adhesion promoter and paraffin and oil additives.
nanocrystallite-viologen electron acceptor complex whose light-induced electron transfer has been demonstrated.
Tetraisopropyl titanate (TIPT) is used for ester exchange reaction.


Tetraisopropyl titanate (TIPT) is used for making metal and rubber, metal and plastic binder, also used as ester exchange reaction and polymerization reaction catalyst and pharmaceutical industry raw materials.
Tetraisopropyl titanate (TIPT) is used polymerization catalyst.


Tetraisopropyl titanate (TIPT) can be used to improve the adherence and crosslinking of resin having group or carboxyl group, used in heat resistant and corrosion resistant coating.
Tetraisopropyl titanate (TIPT) also can be used in the manufacture of glass and glass fiber.


Tetraisopropyl titanate (TIPT) is used transesterification.
Tetraisopropyl titanate (TIPT) can adhere paint, rubber, plastic to metal.
Tetraisopropyl titanate (TIPT) is used as a chemical additive and an intermediate in chemical products.


Tetraisopropyl titanate (TIPT) can only be used in oil system.
Coating: Glass, metals, fillers and pigments can be treated with Tetraisopropyl titanate (TIPT) to give increased surface hardness; adhesion promotion; heat, chemical and scratch resistance; coloring effects; light reflection; iridescence; and corrosion resistance


Tetraisopropyl titanate (TIPT) is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes.
Tetraisopropyl titanate (TIPT) is applied in the formation of a heterosupermolecule consisting of a TiO2


Tetraisopropyl titanate (TIPT) is used catalyst for esterification reactions, and transesterification reactions of acrylic acid and other esters.
Tetraisopropyl titanate (TIPT) is used as Ziegler (Ziegler Natta) catalyst in polymerization reactions such as epoxy resin, phenolic plastic, silicone resin, polybutadiene, etc.


Tetraisopropyl titanate (TIPT) is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes.
Tetraisopropyl titanate (TIPT) is an active component of Sharpless epoxidation as well as involved in the synthesis of chiral epoxides.


Paint additive: Tetraisopropyl titanate (TIPT) can be used as an additive in paints to cross-link -OH functional polymers or binders; to promote adhesion; or to act as a binder itself.
Tetraisopropyl titanate (TIPT) is mainly used as catalyst in esterification reaction or transesterification,also being used as catalyst of polyolefin.


Tetraisopropyl titanate (TIPT) has been proved that it can undergo light-induced electron transfer.
Tetraisopropyl titanate (TIPT) is mainly used for transesterification and condensation reactions in organic synthesis Catalyst.
Tetraisopropyl titanate (TIPT) is often used as a precursor to prepare titanium dioxide (TiO2).


Tetraisopropyl titanate (TIPT) is an active component of sharpless epoxidation as well as involved in the synthesis of chiral epoxides.
In Kulinkovich reaction, Tetraisopropyl titanate (TIPT) is involved as a catalyst in the preparation of cyclopropanes.
Novel metal oxide/phosphonate hybrids were formed from Tetraisopropyl titanate (TIPT) in a two-step sol-gel process.


In Kulinkovich reaction, Tetraisopropyl titanate (TIPT) is involved as a catalyst in the preparation of cyclopropanes.
Tetraisopropyl titanate (TIPT) is used exchange Reaction for Esters
Tetraisopropyl titanate (TIPT) can be used to improve the adherence and crosslinking of resin having alcohol group or carboxyl group, used in heat resistant and corrosion resistant coating.


Tetraisopropyl titanate (TIPT) also can be used in the manufacture of glass and glass fiber.
Tetraisopropyl titanate (TIPT) is used as additives and intermediates in chemical products
Tetraisopropyl titanate (TIPT) is used to make adhesives and as catalysts for transesterification and polymerization


Tetraisopropyl titanate (TIPT) can be used to prepare adhesives for metal and rubber, metal and plastics, catalysts for transesterification and polymerization, and raw materials for pharmaceutical industry.
Tetraisopropyl titanate (TIPT) is used for titanate coupling agent、crosslinking agent and dispersant synthesis.


Tetraisopropyl titanate (TIPT) is mainly used as a catalyst for ester exchange and condensation reactions in organic synthesis.
Tetraisopropyl titanate (TIPT) is often used as a precursor for the preparation of titanium dioxide (TiO2).
Tetraisopropyl titanate (TIPT) can only be used in oil system.


Tetraisopropyl titanate (TIPT) is used catalyst especially for asymmetric induction in organic syntheses; in preparation of nanosized TiO2.
Tetraisopropyl titanate (TIPT) is used complexing agent in sol-gel process.
Starting material for barium-strontium-titanate thin films.


Tetraisopropyl titanate (TIPT) is also used to promote the adhesion of the coating to the surface.
Tetraisopropyl titanate (TIPT) can be directly used as a material surface modifier, adhesive promoter.
Tetraisopropyl titanate (TIPT) is used polymerization catalyst.


A new metal oxide/phosphonate hybrid can be formed from titanium tetraisopropoxide by sol-gel two-step method.
The raw material of barium strontium titanate film.
Tetraisopropyl titanate (TIPT) is used to prepare porous titanosilicates, which are potential ion exchange materials for the removal of radioactive wastes.


Tetraisopropyl titanate (TIPT) is used to form heterogeneous supramolecules composed of TiO2 nanocrystals-violet essence electron acceptor complexes, which have been shown to be capable of light-induced electron transfer.
Tetraisopropyl titanate (TIPT) is used industrial catalyst, pesticide intermediates, plastic rubber auxiliaries, pharmaceutical raw materials.


A new type of metal oxide/phosphonate hybrid can be formed from Tetraisopropyl titanate (TIPT) by a two-step sol-gel process.
Tetraisopropyl titanate (TIPT) is a the raw material for the strontium barium titanate thin film.
Tetraisopropyl titanate (TIPT) is used to prepare porous titanium silicate, which is a potential ion exchange material for removing radioactive waste.


Tetraisopropyl titanate (TIPT) has been demonstrated that heterogeneous supramolecules composed of TiO2 nanocrystals and viologen electron acceptor complexes can undergo photo induced electron transfer.
Tetraisopropyl titanate (TIPT) is perfect for use as a synthesis catalyst and as an ingredient for pharmaceutical coatings.


Tetraisopropyl titanate (TIPT) is mainly used as catalyst for esterification and polymerization of organic synthesis.
Tetraisopropyl titanate (TIPT) is also used as adhesive for metal and rubber, metal and plastic, and used as coating additive and medical organic synthesis.
Tetraisopropyl titanate (TIPT) is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films.


Tetraisopropyl titanate (TIPT) is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes.
Tetraisopropyl titanate (TIPT) is an active component of Sharpless epoxidation as well as involved in the synthesis of chiral epoxides.
Tetraisopropyl titanate (TIPT) is a versatile chemical used in various applications such as catalysis, polymerization, and surface treatment of materials.


Tetraisopropyl titanate (TIPT) is commonly used as a precursor for the synthesis of titanium oxide nanoparticles, which are widely used in nanotechnology applications.
In Kulinkovich reaction, Tetraisopropyl titanate (TIPT) is involved as a catalyst in the preparation of cyclopropanes.


Tetraisopropyl titanate (TIPT) is used catalyst to produce plasticizers, polyesters and methacrylic esters.
Tetraisopropyl titanate (TIPT) is used adhesion promoter.
Novel metal oxide/phosphonate hybrids were formed from Tetraisopropyl titanate (TIPT) in a two-step sol-gel process.


Starting material for barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is used to make porous titanosilicates, potential ion-exchange materials for cleanup of radioactive wastes.
Applied in the formation of a heterosupermolecule consisting of a TiO2 nanocrystallite-viologen electron acceptor complex whose light-induced electron transfer has been demonstrated.


Tetraisopropyl titanate (TIPT) comes in a 500mL bottle and should be handled with care due to its flammable nature.
Tetraisopropyl titanate (TIPT) should be stored in a cool, dry place away from sources of ignition or heat.
Proper protective equipment must be worn when handling Tetraisopropyl titanate (TIPT).


No significant environmental impacts have been reported for Tetraisopropyl titanate (TIPT) if handled properly.
Tetraisopropyl titanate (TIPT) is a type of very lively primary alcohol titanium oxide; it hydrolyzes when contacted with moisture in air.
Tetraisopropyl titanate (TIPT) is mainly used as catalyst in esterification reaction or transesterification,also being used as catalyst of polyolefin.


Tetraisopropyl titanate (TIPT) can be used to improve the adherence and crosslinking of resin having alcohol group or carboxyl group, used in heat resistant and corrosion resistant coating.
Tetraisopropyl titanate (TIPT) also can be used in the manufacture of glass and glass fiber.


Tetraisopropyl titanate (TIPT) can only be used in oil system.
Tetraisopropyl titanate (TIPT) is used to the ester exchange reaction
Intermediates, Tetraisopropyl titanate (TIPT) is used as fertilizer and chemical products


Tetraisopropyl titanate (TIPT) is used for making adhesives, used as ester exchange reaction and polymerization catalyst
Tetraisopropyl titanate (TIPT) is used for making metal and rubber, metal and plastic adhesive
Tetraisopropyl titanate (TIPT) is a type of very lively primary alcohol titanium oxide; it hydrolyzes when contacted with moisture in air.


Tetraisopropyl titanate (TIPT) is mainly used as catalyst in esterification reaction or transesterification,also being used as catalyst of polyolefin.
Tetraisopropyl titanate (TIPT) can be used to improve the adherence and crosslinking of resin having alcohol group or carboxyl group, used in heat resistant and corrosion resistant coating.


Tetraisopropyl titanate (TIPT) also can be used in the manufacture of glass and glass fiber.
Tetraisopropyl titanate (TIPT) is used to make porous titanosilicates, potential ion-exchange materials for cleanup of radioactive wastes.
Tetraisopropyl titanate (TIPT) is used as a catalyst for transesterification reaction with various alcohols under neutral conditions.


Tetraisopropyl titanate (TIPT) can be formed by a sol-gel two-step method.
Tetraisopropyl titanate (TIPT) is used new metal oxide/phosphonate hybrid.
Tetraisopropyl titanate (TIPT) is used cross-linking for polymers.


Tetraisopropyl titanate (TIPT) is used coatings.
Tetraisopropyl titanate (TIPT) is used surface modification (metal, glass)
Applied in the formation of a heterosupermolecule consisting of a TiO2 nanocrystallite-viologen electron acceptor complex whose light-induced electron transfer has been demonstrated.


Novel metal oxide/phosphonate hybrids were formed from Tetraisopropyl titanate (TIPT) in a two-step sol-gel process.
Starting material for barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is used to make porous titanosilicates, potential ion-exchange materials for cleanup of radioactive wastes.


Tetraisopropyl titanate (TIPT) is commonly used as a precursor for the preparation of Titania (TiO2)
Tetraisopropyl titanate (TIPT) is a titanium-based coordination compound, commonly used in the asymmetric Sharpless epoxidation reaction of allylic alcohols.


Tetraisopropyl titanate (TIPT) is also used as a catalyst in Kulinkovich reaction for the synthesis of cyclopropanes.
Tetraisopropyl titanate (TIPT) is used manufacture of scratch resistant glass.
Tetraisopropyl titanate (TIPT) is used in cross linking agent in wire enamel.


Tetraisopropyl titanate (TIPT) is used in chelates of ink & Plasticizers Ind.
Tetraisopropyl titanate (TIPT) is used Chemical Synthesis, Industrial Chemicals, Organic Intermediates.
Tetraisopropyl titanate (TIPT) is commonly used as a precursor for the preparation of Titania (TiO2).
Novel metal oxide/phosphonate hybrids were formed from Tetraisopropyl titanate (TIPT) in a two-step sol-gel process.


Starting material for barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is used to make porous titanosilicates, potential ion-exchange materials for cleanup of radioactive wastes.
Tetraisopropyl titanate (TIPT) can be used as an additive to improve the corrosion resistance of metal surfaces, such as steel and copper.


Tetraisopropyl titanate (TIPT) has high stereoselectivity.
In the paint, Tetraisopropyl titanate (TIPT) is used a variety of polymers or resins play a cross-linking role, improving the anti-corrosion ability of the coating, etc.


Tetraisopropyl titanate (TIPT) is used for transesterification.
Tetraisopropyl titanate (TIPT) is used for heat-resistant surface coatings in paints, lacquers, and plastics; for hardening and cross-linking of epoxy, silicon, urea, melamine, and terephthalate resins and adhesives; and for adhesion of paints, rubber, and plastics to metals.


Tetraisopropyl titanate (TIPT) is also used in catalysts, glass surface treatments, flue gas sorbents, controlled-release pesticides, and dental compositions (to bond to enamel).
Tetraisopropyl titanate (TIPT) is used to make nano-sized titanium dioxide.


Tetraisopropyl titanate (TIPT) can be used as an adhesion promoting and cross-linking agent for hydroxylic compounds or heat and corrosion resistant coatings.
Tetraisopropyl titanate (TIPT) can adhere paint, rubber and plastic to metal.


Tetraisopropyl titanate (TIPT) is used as an additive for the Sharpless asymmetric epoxidation reaction of allyl alcohol.
Applied in the formation of a heterosupermolecule consisting of a TiO2 nanocrystallite-viologen electron acceptor complex whose light-induced electron transfer has been demonstrated.


This alkoxide of titanium(IV) is used in organic synthesis and materials science.
Tetraisopropyl titanate (TIPT) is used as a precursor for the preparation of titanium and barium-strontium-titanate thin films.
Tetraisopropyl titanate (TIPT) is useful to make porous titanosilicates and potential ion-exchange materials for cleanup of radioactive wastes.


Tetraisopropyl titanate (TIPT) is an active component of Sharpless epoxidation as well as involved in the synthesis of chiral epoxides.
In Kulinkovich reaction, Tetraisopropyl titanate (TIPT) is involved as a catalyst in the preparation of cyclopropanes.
Tetraisopropyl titanate (TIPT) is used for the preparation of adhesives, as a catalyst for transesterification and polymerization


Tetraisopropyl titanate (TIPT) is most suitable for use in the glass and glass fiber manufacturing.
Tetraisopropyl titanate (TIPT) can be used as an adhesion promoting and cross-linking agent for hydroxylic compounds or heat and corrosion resistant coatings.


Tetraisopropyl titanate (TIPT) is most suitable for use in the glass and glass fiber manufacturing.
Tetraisopropyl titanate (TIPT) can be used directly or in directly as a catalyst or catlyst additive,as a coating primer or added to formulation as a adhesion promoter and as the base material in the formation fo sol-get systems or nanoparticle systems or products.


Industry uses of Tetraisopropyl titanate (TIPT): Ceramics, Coatings, Polymers (Chemical/Industrial Manufacturing)
Tetraisopropyl titanate (TIPT) can be used as a precursor for ambient conditions vapour phase deposition such as infiltration into polymer thin films.
The production and use of Tetraisopropyl titanate (TIPT) requires precision, expertise, and adherence to strict safety guidelines.


Tetraisopropyl titanate (TIPT)’s wide-ranging applications span several industries.
Its primary use lies within the domain of material science, where Tetraisopropyl titanate (TIPT) is utilized in the creation of ceramics, glasses, and other materials.


Tetraisopropyl titanate (TIPT)’s use to prepare porous titanosilicates, has been utilized to form ion exchange media to treat nuclear wastes in the removal of soluble forms of cesium-137 (137Cs).
Tetraisopropyl titanate (TIPT) also has been shown to have synergistic effects when combined with other additives, such as metal hydroxides or methyl glycosides.


Tetraisopropyl titanate (TIPT) can be used as sharpless oxidation catalyst.
Tetraisopropyl titanate (TIPT) is used synthesize all kinds of titanate coupling agent, cross-linking agent and dispersant.
Tetraisopropyl titanate (TIPT) is most commonly used as a Lewis acid and a Ziegler–Natta catalyst.


Tetraisopropyl titanate (TIPT) is used catalyst to produce plasticizers, polyesters and methacrylic esters.
Tetraisopropyl titanate (TIPT) is used adhesion promoter, Cross-linking for polymers, Coatings, Surface modification (metal, glass)
Tetraisopropyl titanate (TIPT) is ideal to be used as a catalyst to develop polyesters and plasticizers.


Tetraisopropyl titanate (TIPT) is used as a raw material for barium strontium titanate film.
Tetraisopropyl titanate (TIPT) is used to prepare porous titanosilicate, which is a potential ion exchange material for removing radioactive waste.
Tetraisopropyl titanate (TIPT) is used to form heterogeneous supramolecules composed of TiO2 nanocrystals-violet essence electron acceptor complexes.


In the chemical industry, Tetraisopropyl titanate (TIPT) serves as a catalyst or a precursor to other catalysts in processes like the Sharpless epoxidation, a process used to synthesize 2,3-epoxyalcohols from primary and secondary allylic alcohols.
The pharmaceutical industry also harnesses the catalytic properties of Tetraisopropyl titanate (TIPT) for certain types of organic reactions, such as transesterification, condensation, addition reactions and polymerization.


In addition to this, Tetraisopropyl titanate (TIPT) is also used as adhesion promoter, coater, etc.
Tetraisopropyl titanate (TIPT) can be used as an esterification catalyst for plasticizers, polyesters, methacrylic esters, resins, polycarbonates, polyolefins and RTV silicone sealants.


Tetraisopropyl titanate (TIPT) can also be used for coating chemicals as a cross linker for wire enamel varnish, glass and zinc flake coatings.
Tetraisopropyl titanate (TIPT) is most suitable for use in the glass and glass fiber manufacturing.
Tetraisopropyl titanate (TIPT) may be used as an adhesion promoter for packaging ink such as flexo and gravure.


Tetraisopropyl titanate (TIPT) has a wide range of applications in various industries.
Pigment production: Tetraisopropyl titanate (TIPT) is used as a precursor for the production of titanium dioxide (TiO2), a white pigment widely used in the paint, cosmetic, and food industries.


Organic synthesis: Tetraisopropyl titanate (TIPT) is used as a catalyst in organic synthesis reactions, such as the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Polymer synthesis: Tetraisopropyl titanate (TIPT) is used as an initiator for the polymerization of vinyl monomers and as a coupling agent for polymer-polymer and polymer-inorganic material interactions.


Adhesion promoter: Tetraisopropyl titanate (TIPT) can act as an adhesion promoter, improving the adhesion of coatings and adhesives to various substrates.
Electronics: Tetraisopropyl titanate (TIPT) is used in the production of thin-film capacitors and in the fabrication of metal-insulator-metal capacitors.
Surface treatment: Tetraisopropyl titanate (TIPT) can be used for the surface treatment of metals, ceramics, and glass to improve their properties, such as corrosion resistance and adhesion.


These are some of the common applications of Tetraisopropyl titanate (TIPT), and its use may vary depending on the specific needs of each industry.
Tetraisopropyl titanate (TIPT) is used catalyst to produce plasticizers, polyesters, and methacrylic esters.
Tetraisopropyl titanate (TIPT) is used adhesion promoter, Cross-linking for polymers, Coatings, and Surface modification (metal, glass).


Tetraisopropyl titanate (TIPT) is used as a precursor for the production of titanium dioxide (TiO2), a white pigment widely used in paint, cosmetics, and food industries.
Tetraisopropyl titanate (TIPT) is also used as a starting material in the synthesis of other titanium compounds and as a catalyst in organic synthesis.


-TiO2 pigments and films:
Micro- or nano-scale TiO2 pigments can be formed from Tetraisopropyl titanate (TIPT).
Tetraisopropyl titanate (TIPT) can also be used to create a polymeric TiO2 film on surfaces via pyrolytic or hydrolytic processes.

-Hair-making uses of Tetraisopropyl titanate (TIPT):
Tetraisopropyl titanate (TIPT), isopropyl alcohol, and liquid ammonia were heated and dissolved in toluene as a solvent to undergo an esterification reaction.
The reaction product was filtered off by-product ammonium chloride by suction, and the product was obtained by distillation.


-Tetraisopropyl titanate (TIPT) is mainly used as catalyst for transesterification and condensation in organic synthesis.
Tetraisopropyl titanate (TIPT) is often used as precursor to prepare titanium dioxide (titanium dioxide).
A new type of metal oxide / phosphonate hybrids can be formed from four isopropanol titanium by sol-gel two step process.
Raw materials for barium strontium titanate thin films.

Porous titanium silicate is a potential ion exchange material for the removal of radioactive waste.
Photoinduced electron transfer has been demonstrated to occur in heterogeneous supramolecules consisting of nanocrystalline titanium dioxide and viologen electron acceptor complexes.


-Coating Industry uses of Tetraisopropyl titanate (TIPT):
Tetraisopropyl titanate (TIPT) is commonly used as a catalyst in the coating industry.
Tetraisopropyl titanate (TIPT)'s purpose in this field involves promoting the curing process of coatings and improving their overall performance.
The mechanism of action in coatings involves the initiation and acceleration of chemical reactions, leading to the formation of a durable and protective coating layer.


-Polymer Industry uses of Tetraisopropyl titanate (TIPT):
Tetraisopropyl titanate (TIPT) is also utilized in the polymer industry as a crosslinking agent.
Tetraisopropyl titanate (TIPT)'s purpose in this field involves creating strong chemical bonds between polymer chains, resulting in enhanced mechanical properties and stability of the polymers.
The mechanism of action in polymer crosslinking involves the formation of covalent bonds between the Tetraisopropyl titanate (TIPT) and the polymer chains, leading to a three-dimensional network structure.



TETRAISOPROPYL TITANATE (TIPT) USAGE IN GLASS INDUSTRY:
Tetraisopropyl titanate (TIPT) is commonly used as a cross-linking agent and catalyst in the glass industry.

*Anti-reflective coatings:
Tetraisopropyl titanate (TIPT) is often used as a cross-linking agent in anti-reflective coatings for glass.
The coating helps to reduce glare and improve visibility, making Tetraisopropyl titanate (TIPT) ideal for applications like eyeglasses, camera lenses, and flat panel displays.


*Self-cleaning coatings:
Tetraisopropyl titanate (TIPT) is also used to create self-cleaning coatings for glass.
When exposed to sunlight, the coating reacts with oxygen to produce free radicals that break down organic matter on the surface of the glass.
This helps to keep the glass clean and reduces the need for manual cleaning.


*Pigments:
As I mentioned earlier, Tetraisopropyl titanate (TIPT) is used as a precursor for the synthesis of titanium dioxide (TiO2) nanoparticles.
These nanoparticles are used as pigments in glass and ceramic applications, providing improved optical properties and color saturation.
They are often used in products like decorative glassware, ceramic tiles, and automotive glass.


*Scratch-resistant coatings:
Tetraisopropyl titanate (TIPT) can also be used to create scratch-resistant coatings for glass.
When added to the coating, Tetraisopropyl titanate (TIPT) reacts with the hydroxyl groups on the surface of the glass to create a durable, cross-linked network.
This network helps to protect the glass from scratches, abrasion, and chemical damage, making Tetraisopropyl titanate (TIPT) ideal for applications like smartphone screens and protective eyewear.



TETRAISOPROPYL TITANATE (TIPT) USAGE IN INK INDUSTRY:
Tetraisopropyl titanate (TIPT) is commonly used in the ink industry as a cross-linking agent and as a catalyst for polymerization reactions.
Here are some specific ways that Tetraisopropyl titanate (TIPT) is used in the ink industry:


*UV-curable inks:
Tetraisopropyl titanate (TIPT) is often used as a cross-linking agent in UV-curable inks.
When exposed to UV light, the ink undergoes a polymerization reaction that cross-links the ink molecules and hardens the ink film. Tetraisopropyl titanate (TIPT) can be added to the ink formulation to promote cross-linking and improve the ink’s adhesion, durability, and resistance to abrasion and chemical attack.


*Pigment dispersions:
Tetraisopropyl titanate (TIPT) is also used as a dispersant in pigment dispersions for ink formulations.
Tetraisopropyl titanate (TIPT) helps to stabilize the pigment particles and prevent them from settling out of the ink.
This improves the color consistency and print quality of the ink.


*Metal printing:
Tetraisopropyl titanate (TIPT) can be used as a catalyst for the polymerization of acrylic resins used in metal printing.
The resin is applied to the metal substrate as an ink and then cured using Tetraisopropyl titanate (TIPT) as a catalyst.
This creates a durable and scratch-resistant coating on the metal surface.


*Inkjet printing:
Tetraisopropyl titanate (TIPT) can be added to inkjet inks as a cross-linking agent to improve the ink’s adhesion and durability on various substrates, such as paper, plastic, and metal.

Overall, Tetraisopropyl titanate (TIPT) is a valuable tool in the ink industry, helping to improve the performance and quality of ink formulations.
Tetraisopropyl titanate (TIPT)'s ability to promote cross-linking, stabilize pigments, and catalyze polymerization reactions makes it a versatile material for ink manufacturers.



FEATURES OF TETRAISOPROPYL TITANATE (TIPT):
*Organic compound composed of titanium and isopropyl groups
*Colorless liquid with a low melting point
*Low toxicity and is considered relatively safe to handle
*Reacts readily with water and air



BENEFITS OF TETRAISOPROPYL TITANATE (TIPT):
*Versatile:
Tetraisopropyl titanate (TIPT) is a versatile compound that can be used in various industries, including pigment production, organic synthesis, and polymer synthesis.

*Efficient:
As a catalyst, Tetraisopropyl titanate (TIPT) can facilitate organic reactions in a fast and efficient manner.

*High-quality products:
Tetraisopropyl titanate (TIPT) is used as a precursor for the production of high-quality titanium dioxide pigment used in paints, cosmetics, and food products.

*Precursor for other compounds:
Tetraisopropyl titanate (TIPT) is used as a starting material for the synthesis of other titanium compounds.

*Adhesion promoter:
Tetraisopropyl titanate (TIPT) can also act as an adhesion promoter, improving the adhesion of coatings and adhesives to various substrates.

Overall, the features and benefits of Tetraisopropyl titanate (TIPT) make it a valuable compound in various industries, providing an efficient and versatile solution for the production of high-quality products.



SHELF LIFE OF TETRAISOPROPYL TITANATE (TIPT):
Under proper storage conditions, the shelf life of Tetraisopropyl titanate (TIPT) is 12 months.



REACTIONS OF TETRAISOPROPYL TITANATE (TIPT):
*Catalyst for the synthesis of acyclic epoxy alcohols and allylic epoxy alcohols.
*Useful for diastereoselective reduction of alpha-fluoroketones.
*Catalyzes the asymmetric allylation of ketones.
*Reagent for the synthesis of cyclopropylamines from aryl and alkenyl nitriles.
*Useful for racemic and/or enantioselective addition of nucleophiles to aldehydes, ketones and imines.
*Catalytic intramolecular formal [3+2] cycloaddition.
*Catalyst for the synthesis of cyclopropanols from esters and organomagnesium reagents



PREPARATION OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) is prepared by treating titanium tetrachloride with isopropanol.
Hydrogen chloride is formed as a coproduct:
TiCl4 + 4 (CH3)2CHOH → Ti{OCH(CH3)2}4 + 4 HCl



PROPERTIES OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) reacts with water to deposit titanium dioxide:
Ti{OCH(CH3)2}4 + 2 H2O → TiO2 + 4 (CH3)2CHOH
This reaction is employed in the sol-gel synthesis of TiO2-based materials in the form of powders or thin films.

Typically water is added in excess to a solution of the alkoxide in an alcohol.
The composition, crystallinity and morphology of the inorganic product are determined by the presence of additives (e.g. acetic acid), the amount of water (hydrolysis ratio), and reaction conditions.

Tetraisopropyl titanate (TIPT) is also used as a catalyst in the preparation of certain cyclopropanes in the Kulinkovich reaction.
Prochiral thioethers are oxidized enantioselectively using a catalyst derived from Ti(O-i-Pr)4.



SOLUBILITY OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) is soluble in anhydrous ethanol, ether, benzene and chloroform.



NOTES OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) is moisture sensitive.
Store Tetraisopropyl titanate (TIPT) in cool place.
Keep Tetraisopropyl titanate (TIPT) container tightly closed in a dry and well-ventilated place.
Tetraisopropyl titanate (TIPT) is incompatible with strong oxidizing agents and strong acids.
Tetraisopropyl titanate (TIPT) reacts with water to produce titanium dioxide.



PROPERTIES OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) is soluble in anhydrous ethanol, ether, benzene and chloroform.



NOTES OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) is moisture sensitive.
Store Tetraisopropyl titanate (TIPT) in cool place.
Keep Tetraisopropyl titanate (TIPT) container tightly closed in a dry and well-ventilated place.

Tetraisopropyl titanate (TIPT) is incompatible with strong oxidizing agents and strong acids.
Tetraisopropyl titanate (TIPT) reacts with water to produce titanium dioxide.



KEY FEATURES OF TETRAISOPROPYL TITANATE (TIPT):
*Balanced pH value, Purity
*Non-toxic
*Safe to use



AIR AND WATER REACTIONS OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) fumes in the air.
Tetraisopropyl titanate (TIPT) is soluble in water.
Tetraisopropyl titanate (TIPT) decomposes rapidly in water to form flammable isopropyl alcohol.



REACTIVITY PROFILE OF TETRAISOPROPYL TITANATE (TIPT):
Metal alkyls, such as Tetraisopropyl titanate (TIPT), are reducing agents and react rapidly and dangerously with oxygen and with other oxidizing agents, even weak ones.
Thus, they are likely to ignite on contact with alcohols.



BACKGROUND OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) has a rich history in the realm of chemical synthesis.
First discovered in the 1950s, Tetraisopropyl titanate (TIPT) quickly became an essential tool due to its unique chemical properties.
As an alkoxide of titanium, Tetraisopropyl titanate (TIPT) is an organometallic compound, meaning it is part of a class of compounds that contain a metal directly bonded to an organic molecule, which gives them unique properties.

Tetraisopropyl titanate (TIPT) is often used in a process known as sol-gel synthesis.
In this method, a solution (sol) is gradually transitioned to a solid (gel) form.
Tetraisopropyl titanate (TIPT) is used in this process because it can be easily hydrolyzed (reacted with moisture/water) and condensed to first form a colloidal structure and upon further condensation, a connected porous network of titanium dioxide.

This gel can be further aged and dried through supercritical (aerogel), thermal (xerogel) or freeze drying (cryogel) to form a solid powder end product with multiple levels of structure, functionality, and porosity.
Moreover, Tetraisopropyl titanate (TIPT) is instrumental in metal-organic chemical vapor deposition (MOCVD).

In this process, a volatile precursor like Tetraisopropyl titanate (TIPT) is used to produce high-quality, thin film materials with atomic level precision control of thickness with uniformity and high repeatability.
These materials are then used in a variety of applications, from microelectronics to solar cells.

While the value of Tetraisopropyl titanate (TIPT) is well-established, its flammability and sensitivity to moisture and air while beneficial in the sol-gel or MOCVD processes pose significant handling challenges.
It is essential that Tetraisopropyl titanate (TIPT)'s transport and storage be carefully controlled to avoid inherent hazards and also contamination and degradation.

In response to these challenges, the industry has developed specialized handling equipment and stringent environmental control measures to maintain the safety and integrity of this important chemical precursor.
The evolution of Tetraisopropyl titanate (TIPT) reflects the wider trends in the chemical industry: the constant pursuit of better and safer synthetic methods, the adaptation to increasingly stringent environmental standards, and the development of cutting-edge applications in high-tech industries.

Through its versatile applications, Tetraisopropyl titanate (TIPT) is significantly contributing to enhancing chemical synthesis, material science, and sustainability in economic and environmental efforts."



CHEMICAL AND PHYSICAL PROPERTIES OF TETRAISOPROPYL TITANATE (TIPT):
Character light yellow liquid, smoke in humid air.
boiling point 102~104 ℃
freezing point 14.8 ℃
relative density 0.954g/cm3
refractive index 1.46
soluble in a variety of organic solvents.



PURIFICATION METHODS OF TETRAISOPROPYL TITANATE (TIPT):
Dissolve Tetraisopropyl titanate (TIPT) in dry *C6H6 , filter if a solid separates, evaporate and fractionate.
Tetraisopropyl titanate (TIPT) is hydrolysed by H2O to give solid Ti2O(iso-OPr)2 m ca 48o



SUMMARY OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT), often abbreviated TTIP, is a crucial compound used in many modern industrial processes that rely on organic synthesis and materials science.

More specifically, Tetraisopropyl titanate (TIPT) is frequently used in the asymmetric Sharpless epoxidation reaction of allylic alcohols, and as a catalyst in the Kulinkovich reaction for the synthesis of cyclopropanes.
Most commonly, Tetraisopropyl titanate (TIPT) serves as a precursor for the production of titanium dioxide (TiO2), a substance found in a multitude of applications from paint to sunscreen.

However, Tetraisopropyl titanate (TIPT)’s flammability and sensitivity to moisture and air presents challenges for its storage and transport.
With the use of appropriate packaging and transport solutions, as well as meticulous environmental control, Tetraisopropyl titanate (TIPT)’s possible to overcome this challenge.



PRODUCTION METHODS OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) reacts with water to deposit titanium dioxide:
Ti{OCH(CH3)2}4 + 2 H2O → TiO2 + 4 (CH3)2CHOH

This reaction is employed in the sol-gel synthesis of TiO2-based materials.
Typically water is added to a solution of the alkoxide in an alcohol.
The nature of the inorganic product is determined by the presence of additives (e.g. acetic acid), the amount of water, and the rate of mixing.

Tetraisopropyl titanate (TIPT) is a component of the Sharpless epoxidation, a method for the synthesis of chiral epoxides.
Tetraisopropyl titanate (TIPT) is also used as a catalyst for the preparation of certain cyclopropanes in the Kulinkovich reaction.
Prochiral thioethers are oxidized enantioselectively using catalyst derived from Ti(O-i-Pr)4.



PREPARATION OF TETRAISOPROPYL TITANATE (TIPT):
Tetraisopropyl titanate (TIPT) is prepared by treating titanium tetrachloride with isopropanol.
Hydrogen chloride is formed as a coproduct:
TiCl4 + 4 (CH3)2CHOH → Ti{OCH(CH3)2}4 + 4 HCl



PHYSICAL and CHEMICAL PROPERTIES of TETRAISOPROPYL TITANATE (TIPT):
Physical state: Liquid
Color: Light yellow
Odor: Alcohol-like
Melting point/freezing point: Melting point/range: 14 - 17 °C
Initial boiling point and boiling range: 232 °C
Flammability (solid, gas): Not available
Upper/lower flammability or explosive limits: Not available
Flash point: 41 °C
Autoignition temperature: Not available
Decomposition temperature: Not available
pH: Not available
Viscosity:
Kinematic viscosity: Not available
Dynamic viscosity: 3 mPa.s at 25 °C
Water solubility: Insoluble
Partition coefficient (n-octanol/water): Not available

Vapor pressure: 1.33 hPa at 63 °C
Density: 0.96 g/mL at 20 °C
Relative density: 0.96 at 25 °C
Relative vapor density: Not available
Particle characteristics: Not available
Explosive properties: Not available
Oxidizing properties: None
Other safety information: Not available
Molecular Weight: 284.22 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 284.1467000 g/mol
Monoisotopic Mass: 284.1467000 g/mol
Topological Polar Surface Area: 92.2 Ų
Heavy Atom Count: 17

Formal Charge: 0
Complexity: 10.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes
Appearance: Clear liquid
Density (D20): 0.96-1.00 g/cm3
Titanium Contents: 16.62-16.80%
Refractive Index (D20): 1.465
pH value: Approximately 6
Freezing point: >13 °C
Boiling point: 156 °C at 100 mmHg
CAS Number: 546-68-9

Molecular Formula: C12H28O4Ti
Molecular Weight: 284.22 g/mol
MDL Number: MFCD00008871
MOL File: 546-68-9.mol
Melting point: 14-17 °C (literature value)
Boiling point: 232 °C (literature value)
Density: 0.96 g/mL at 20 °C (literature value)
Vapor pressure: 60.2 hPa at 25 °C
Refractive index: n20/D 1.464 (literature value)
Flash point: 72 °F
Storage temperature: Flammable area
Solubility: Soluble in anhydrous ethanol, ether, benzene, and chloroform
Form: Liquid
Color: Colorless to pale yellow
Specific Gravity: 0.955

Water Solubility: Hydrolysis
Freezing Point: 14.8 °C
Sensitive: Moisture Sensitive
Hydrolytic Sensitivity: 7 - Reacts slowly with moisture/water
Merck Index: 14,9480
BRN: 3679474
Stability: Stable, but decomposes in the presence of moisture.
Incompatible with aqueous solutions, strong acids, strong oxidizing agents.
InChIKey: VXUYXOFXAQZZMF-UHFFFAOYSA-N
LogP: 0.05
Indirect Additives used in Food Contact Substances: Titanium tetraisopropylate
FDA 21 CFR: 175.105
CAS DataBase Reference: 546-68-9
FDA UNII: 76NX7K235Y
EPA Substance Registry System: 2-Propanol, titanium(4+) salt (546-68-9)



FIRST AID MEASURES of TETRAISOPROPYL TITANATE (TIPT):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rnse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAISOPROPYL TITANATE (TIPT):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TETRAISOPROPYL TITANATE (TIPT):
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAISOPROPYL TITANATE (TIPT):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TETRAISOPROPYL TITANATE (TIPT):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities
Storage conditions:
Handle under nitrogen, protect from moisture.
Store under nitrogen.
Keep container tightly closed in a dry and well-ventilated place.
Hydrolyzes readily



STABILITY and REACTIVITY of TETRAISOPROPYL TITANATE (TIPT):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
May decompose on exposure to moist air or water.
-Possibility of hazardous reactions:
No data available

Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a clear colorless viscous liquid.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a water-soluble, colorless, odorless, and stable compound with a molecular formula of C8H24O12P2S.


CAS Number: 55566-30-8
EC Number: 259-709-0
MDL number: MFCD23102118
Linear Formula: [(HOCH2)4P]2(SO4)
Molecular Formula: C8H24O12P2S


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is also effective in controlling microbial growth in drilling muds and stimulation fluids for oil and gaswells. Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is characterized by its low solidity point and good stability.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can easily dissolve in water and can be preserved for a long time.


In 1995, the US EPA ratified it with zero toxicity and awarded it with US Green Chemical prize due to its properties of high efficacy, low toxicity and low rudimental.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a quaternary phosphonium compound whose positive charge makes it an effective biocide by disrupting the cell membrane of microorganisms.


The presence of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) in water can indicate the use of biocides in water treatment or oil and gas production, and it is therefore important to measure its concentration to assess potential environmental impacts.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a Crystalline solid.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is available commercially as an aqueous solution
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a versatile and promising compound with a wide range of potential applications in various fields of research and industry.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is stable, water-soluble, and has shown excellent antimicrobial properties against a broad range of microorganisms.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is currently being investigated for its potential use in water treatment, papermaking, agriculture, and biomedical applications.


Future research in the field may focus on the development of more stable and efficient forms of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS), as well as the identification of new potential applications.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is a kind of environmental-friendly water treatment microbiocide which is made of tetrakis(hydroxymethyl)phosphonium sulfate (THPS 75%) solution.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can withhold sulfate reducing bacteria (SRB), most of aerobic bacteria including microorganisms that form biofilm in enhanced oil recovery process, production and other supporting systems such as water injection equipments, well water disposal facilities, water holding tanks, recirculating water treatment systems and pipelines.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is also effective in controlling microbial growth in drilling muds and stimulation fluids for oil and gas wells. Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is characterized by its low solidity point and good stability.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an extremely effective biocide against a wide range of micro-organisms including, algae, fungi and bacteria.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is aqueous solution of tetrakis(hydroxymethyl) phosphonium sulfate.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a broad-spectrum biocide developed to inhibit the growth of algae, bacteria, yeasts and fungi in process waters used in various industrial applications.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a clear colorless viscous liquid.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an environmental friendly bactericide with good water solubility, low solidifying point, stable chemical performance, long shelf life, new-type, high-efficiency,wide-spectrum etc.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is based on tetrakis phosphonium sulphate.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a biocide effective against micro pest in industrial cooling systems, oil field operations, and paper-making industry.


Its advantage is that Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) will soon degrade to a non-toxic substance immediately after use.
In 1997, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) passed the attestation in the United States of America and was formally put into use in the field of environmental protection.


In the same year, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) was awarded with American Green Chemicals Award.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a rapid acting, powerful microbiocide which has been designed to control bacteria in oilfield water-flood operations and production systems.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be used to control reservoir souring in oilfields contaminated with sulphate reducing bacteria and alleviate production problems associated with iron sulphide deposition.
With a relatively low order of aquatic toxicity and being both biodegradable and nonbioaccumulative, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is approved for use in many environmentally sensitive areas of the world including the North Sea.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is supplied as a liquid formulation which is non-foaming, fully miscible with water and insoluble in oils.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a clear colorless viscous liquid.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a safe aqueous solution with antimicrobial properties that is significantly less toxic, effective at lower concentrations, and more biodegradable than other traditional biocides.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is available in different levels of active phosphorous contents to suit different applications.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an organophosphorus compound .
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an environmental friendly bactericide with good water solubility, low solidifying point, stable chemical performance, long shelf life, new-type, high-efficiency, wide-spectrum etc.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a kind of environmental anti-microbial reagent.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS)’s characterized by its low solidity point and fine stability.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide can be reserved for a long time and easily dissolve in water.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a new environmental pesticide with high efficacy, low toxicity, and low rudimental.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) chemicals can kill germ and aquatic plants.
In 1995, the US EPA (Environmental Protection Agency) ratified Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) with zero toxicity and awarded it the US

Green Chemical prize.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an organophosphorus compound with the chemical formula [P(CH2OH)4]Cl.
The cation P(CH2OH)4+ is four-coordinate, as is typical for phosphonium salts.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS), which is derived from tetrakis(hydroxymethyl)phosphonium chloride, is an intermediate in the preparation of the water-soluble ligand 1,3,5-triaza-7-phosphaadamantane (PTA).
This conversion is achieved by treating hexamethylenetetramine with formaldehyde and tris(hydroxymethyl)phosphine.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can also be used to synthesize the heterocycle, N-boc-3-pyrroline by ring-closing metathesis using Grubbs' catalyst (bis(tricyclohexylphosphine)benzylidineruthenium dichloride).
N-Boc-diallylamine is treated with Grubbs' catalyst, followed by tris(hydroxymethyl)phosphine.


The carbon-carbon double bonds undergo ring closure, releasing ethene gas, resulting in N-boc-3-pyrroline.
The hydroxymethyl groups on THPC undergo replacement reactions when Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is treated with α,β-unsaturated nitrile, acid, amide, and epoxides.


For example, base induces condensation between Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) and acrylamide with displacement of the hydroxymethyl groups. (Z = CONH2)
[P(CH2OH)4]Cl + NaOH + 3CH2=CHZ → P(CH2CH2Z)3 + 4CH2O + H2O + NaCl


Similar reactions occur when Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is treated with acrylic acid; only one hydroxymethyl group is displaced, however.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a clear straw colored liquid that is between 75-77% pure.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a clear colorless viscous liquid.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is water soluble.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is non flammable.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is characterized by its low solidity point and good stability.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can easily dissolve in water and can be preserved for a long time.
In 1995, the US EPA ratified Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) with zero toxicity and awarded it with US Green Chemical prize due to its properties of high efficacy, low toxicity and low rudimental.


The advantage is Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) will soon degrade to a nontoxic substance immediately after use.
Also Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be applied to fabric coating, obviously improving ýÿflame retarding property.
In 1997, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) passed the attestation in the United States of America and was formally put into use in the field of environmental protection.


In the same year, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) was awarded with American Green Chemicals Award.
In the petroleum industry, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) exhibits excellent activity against problem microorganisms.
In particular Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is extremely effective against sulphate reducing bacteria ( S.R.B), a major cause of hydrogen sulphide souring and corrosion.


Formulations containing Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) may be used in many applications where microbiological contamination is present and they have extensive use in enhanced oil recovery injection water systems, topside recovery systems, pipeline protection and storage.
Many benefits of using Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) formulations are very important in industrial water treatment applications.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) produces a rapid kill against a broad spectrum of bacteria and when suitably formulated with a surfactant it readily eradicates unwanted biofilms.
The excellent toxicity profile of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) and ease of deactivation to a virtually non toxic substance makes it an ideal biocide to use when cooling water is discharged into ecologically sensitive waters.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is compatible with all types of water used in cooling systems and effective minimum dose levels can be quickly achieved through use of an easy on-site analytical method.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can simply dissolve in water and also can be maintained for a long period.


In 1995, the United States environmental protection agency ratified Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) with absolutely no toxicity and awarded it with US green chemical prize because of its characteristics associated with high efficacy, low toxicity and, also low rudimental.
The global Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) market, in terms of value, is estimated to account for nearly USD 202 million in 2019, to reach approximately USD 279 million by 2025.


Factors such as rise in demand for biocides such as Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) are increasingly used in hydraulic fracturing operations based on the condition of the phase that includes factors such as aerobic and anaerobic conditions, temperature, and preference over other toxic biocides are factors that are projected to drive the growth of this market.



USES and APPLICATIONS of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
The primary use for Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is controlling microbial growth in oil field applications such as injection water systems, drilling muds, packer fluids, completion and workover fluids.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) also be used in water treatment, fire retardant treatment of textiles, leather softening, paper making and other industries.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is often used in oil field drilling, fishery as germicidal agent.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used to make crease-resistant and flame-retardant finishes for textiles, e.g., children's sleepwear.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is primarily used as a flame retardant additive and can also be used as a fungicide.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is recommended for use in cotton, leather, and polyester products.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is also used as a biocide.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an organic molecule that is commonly used as a biocide or biostat in various applications, such as water treatment, oil and gas production, and cooling tower water treatment.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a cationic molecule that is effective in controlling microorganisms, algae and biofilms in water systems.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an environment-friendly phosphonium salt biocide applied in industrial cooling systems, oil field operations, and paper-making industry.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can degrade to a nontoxic substance immediately after use.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is also applied as flame retardant in cotton, dacron-cotton fibers.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an environmentally friendly bactericide with good water solubility, low solidifying point, stable chemical performance, long shelf life, new-type, high-efficiency, wide-spectrum, Etc.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is internationally acknowledged as a long lasting flame-retardant product for the treatment of pure cotton and polyester cotton.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used in formulation or re-packing, at industrial sites and in manufacturing.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is being reviewed for use as a biocide in the EEA and/or Switzerland, for: product preservation, preservation for liquid systems, controlling slimes.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used in the following products: leather treatment products.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used for the manufacture of: textile, leather or fur and chemicals.
Release to the environment of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can occur from industrial use: as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).


Release to the environment of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can occur from industrial use: manufacturing of the substance.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has applications as a precursor to fire-retardant materials, as well as a microbiocide in commercial and industrial water systems.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can also be used to synthesize the heterocycle, N-boc-3-pyrroline by ring-closing metathesis using Grubbs' catalyst (bis(tricyclohexylphosphine)benzylidineruthenium dichloride).
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is mainly used in water treatment systems, oil field operations, and paper-making industry.


The advantage is Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) will soon degrade to a nontoxic substance immediately after use.
Also Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be applied to fabric coating as flame retardant, obviously improving flame retarding property.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used in water treatment and oil field as bactericide.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is also used as flame-retardant as it an internationally acknowledged flame-retardants for pure cotton and polyester cotton and its flame-retarding effect can remain for a long time.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is mainly used in water treatment systems, oil field operations, and paper-making.


The advantage is Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) will soon degrade to a nontoxic substance immediately after use.
Also, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide can be applied to fabric coating as a flame retardant, improving the flame-retarding property.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used as a flame retardant in textiles, especially cotton and as a cease and rot resistance agent in fabrics.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) acts as a biocide against SRB (sulfate reducing bacteria known as Desulfuvibrio Desulfuricans) which produces enzymes to accelerate reduction reaction of sulfates to corrosive hydrogen sulfide which causes corrosion of iron material in water system.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is used precursors in flame retardant manufacture process, biocide in water system, and Tanning agent in the leather industry.
One of the main applications is to use Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) as a Tanning agent in the leather industry.


In this case Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be used as chrome-free (metal free) tanning system in the wet white process.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can give the benefits of a lower allergology phenomena and a better biodegradability
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is an internationally acknowledged flame-retardants for pure cotton and polyester cotton and its flame-retarding effect can remain for a long time.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can withhold sulfate reducing bacteria (SRB), most of aerobic bacteria including microorganisms that form biofilm in enhanced oil recovery process, production and other supporting systems such as water injection equipments, well water disposal facilities, water holding tanks, recirculating water treatment systems and pipelines.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is also effective in controlling microbial growth in drilling muds and stimulation fluids for oil and gaswells.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a biocide effective against micropest in industrial cooling systems, oil field operations, and paper-making industry.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is a kind of environmental-friendly water treatment microbiocide which is made of tetrakis(hydroxymethyl)phosphonium sulfate (THPS 75%) solution.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can withhold sulfate reducing bacteria (SRB).


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has been widely used in the oil and gas industry for microbial control, as well as in water treatment and papermaking applications.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can easily withhold sulfate-reducing microorganisms.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has also been studied as a potential biocide, alternative to traditional chlorine-based disinfectants, due to its low toxicity and environmental impact.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a type of environmental-friendly water treatment micro biocide that is made of THPS chemicals.


Most of the aerobic bacteria such as microorganisms form biofilm inside the enhanced oil process of recovery, manufacturing, and also other supporting systems.
For example water injection equipment, well water disposal facilities, water holding tanks, recirculating water treatment systems, as well as pipelines.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can also be good at managing bacterial development in drilling muds and also stimulation liquids for gas and oil wells.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is actually known for its low solidity point and excellent stability.


By application, Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) market is segmented into oil & gas, water treatment, leather, textile, and others including paper & paperboard manufacturing; paints, coatings, and emulsion; agriculture; and aquaculture.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has preservative properties and provides high-temperature stability and prolonged downhole protection in oilfields, thereby making it a preferred choice in the oil & gas industry.


However, it is the biocidal function of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS), which is encouraging its increasing use in the oil & gas industry.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has been the most widely used biocide, followed by glutaraldehyde during oil & gas operations.


Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) biocide is a kind of environmental-friendly water treatment microbiocide which is made of tetrakis(hydroxymethyl)phosphonium sulfate (THPS 75%) solution.


-Advantage of the wet white tanned leathers, using Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) offers:
*a light color and pastel shades
*They can reach shrink temperatures of at least 70 grad C
*High softness
*Good lightness
*Feeling of naturalness
*Pleasant to the touch
*Beauty that lasts for a long time
*Can be burned without the risk of hexavalent chromium formation


-Applications in Scientific Experiments:
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has been used in a range of scientific experiments, including in the study of water treatment, papermaking, and microbial control in the oil and gas industry.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has also been investigated as an alternative disinfectant to chlorine, due to its low toxicity and environmental impact.


-Application in textiles of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has industrial importance in the production of crease-resistant and flame-retardant finishes on cotton textiles and other cellulosic fabrics.

A flame-retardant finish can be prepared from THPC, in which Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is treated with urea.
The urea condenses with the hydroxymethyl groups on Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS).
The phosphonium structure is converted to phosphine oxide as the result of this reaction.

[P(CH2OH)4]Cl + NH2CONH2 → (HOCH2)2POCH2NHCONH2 + HCl + HCHO + H2 + H2O
This reaction proceeds rapidly, forming insoluble high molecular weight polymers.
The resulting product is applied to the fabrics in a "pad-dry process."

This treated material is then treated with ammonia and ammonia hydroxide to produce fibers that are flame-retardant.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can condense with many other types of monomers in addition to urea.
These monomers include amines, phenols, and polybasic acids and anhydrides.



SYNTHESIS AND REACTIONS OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be synthesized with high yield by treating phosphine with formaldehyde in the presence of hydrochloric acid.
PH3 + 4 H2C=O + HCl → [P(CH2OH)4]Cl
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) converts to tris(hydroxymethyl)phosphine upon treatment with aqueous sodium hydroxide:
[P(CH2OH)4]Cl + NaOH → P(CH2OH)3 + H2O + H2C=O + NaCl



REACTIVITY PROFILE OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is incompatible with oxidizing materials and alkalis.



PHYSICAL AND CHEMICAL PROPERTIES OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a hygroscopic, water-soluble, and thermally stable compound with a melting point of 140-145 °C.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has a molecular weight of 406.28 g/mol and is highly soluble in water, with a solubility of approximately 1064 g/L at 20°C.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) exhibits strong oxidizing properties and can decompose upon exposure to high temperatures or light.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS)'s pH ranges from 2-5, and it has a negative zeta potential in water.



ADVANTAGES OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
*Effective against algal, fungal and bacterial species
*Exceptional environmental profile
*Highly effective against legionella pneumophilla



PROPERTY OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is a kind of environmental anti-microbial reagent.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS)'s characterized by its low solidity point and fine stability.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be reserved for long time and can easily dissolve in water.

Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS)'s a kind of new environmental pesticide with high efficacy, low toxicity and low rudimental.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can kill germ and aquatic plants.
In 1995, the EPA of the United States ratified Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) with zero toxicity and awarded it with US Green Chemical prize.



PREPARATION OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) may be obtained by reaction between PH3 (phosphine, co-product of sodium hypophosphite), sulfuric acid and formaldehyde.



SYNTHESIS METHODS OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is synthesized by the following methods.
*Using hydrogen chloride as the catalyst and phosphine and alkyl aldehydes as the reaction raw materials.
*Using formaldehyde and phosphine as reaction raw materials, controlling pressure and temperature in a certain range, formaldehyde phosphine reacts in the presence of a small amount of dispersed metal or compound, through a two-step sequential reaction, i.e., using phosphine with excess formaldehyde under high-pressure, controlling a certain temperature to obtain a solution of trimethylolphos hemiacetal, and finally treated with acid.
*Metal phosphide, formaldehyde, and inorganic acids are used as raw materials.



CURRENT STATE OF RESEARCH, TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Research on Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is ongoing, with several researchers investigating its potential applications in various fields, including biomedicine and nanotechnology.
Recent studies have explored the use of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) in the treatment of acute lymphoblastic leukemia, as well as in the synthesis of silver nanoparticles for use in biomedical applications.

Potential Implications in Various Fields of Research and Industry
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has the potential to be widely used in various fields, including water treatment, agriculture, and consumer products.

Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has been shown to have excellent biocidal properties against a broad range of microorganisms, making it a potential alternative to traditional disinfectants.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has also been studied as a potential antimicrobial agent for use in agriculture and food processing, as well as in the synthesis of paper and textiles.



WATER TREATMENT, TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) should be added to a waterflood system at a point where uniform mixing will occur
*First step: add 93 -350 ppm Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) chemical for a noticeably fouled system.
When added to a flowing system, slug dose for 2 -6 hours based on flow rates. Repeat as necessary until control is achieved.

*Second step: once control has been achieved.
Add 14 -98 ppm THPS biocide weekly or as needed to maintain control.
As for continuous treatment, THPS can be dosed continuously at a level of 14 -67 ppm.



OIL AND GAS PRODUCTION AND TRANSMISSION SYSTEMS AND PIPELINE, TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) should be added at a point in the pipeline where uniform mixing will occur.
The application should be conducted to ensure maximum distribution of products through the internal surface of the pipeline by adding an amount of biocide which eventually comes out the other end of the pipeline.

The criteria for the success of the treatment will be a reduction in the bacterial count and/or corrosion rates.
Adding steps is the same as that of water flooding.
As for continuous treatment, tetrakis hydroxymethyl phosphonium sulfate can be dosed continuously at a level of 14 -100 ppm.



DRILLING-MUDS, WELL COMPLETION AND WORKOVER FLUIDS, TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) should be added to these fluids at a point where uniform mixing will occur.
Add 33-1400 ppm of product to a freshly prepared fluid depending on the severity of contamination.



GAS STORAGE WELL SYSTEMS, TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Individual injection wells should be treated with Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) at the same dosage and same steps as described underwater flooding.
Injections should be repeated as needed to maintain control.
Individual drips should be treated with a sufficient quantity of product to produce a concentration of 33.3 -133.3 ppm when diluted by the water present in the drip.
Injections should be repeated as needed to maintain control.



BIOLOGICAL PROPERTIES OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has been extensively studied for its biocidal properties against a broad range of microorganisms, including bacteria, fungi, and algae.
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has been shown to exhibit excellent antimicrobial activity, with the ability to penetrate bacterial membranes and disrupt intracellular functions.
Studies have also indicated that Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) has low toxicity to aquatic organisms, with minimal environmental impact.



SYNTHESIS AND CHARACTERIZATION OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) is synthesized by a reaction between phosphorous acid and formaldehyde in the presence of sulfuric acid.
The synthesis process involves multistep reactions, where phosphorous acid is first oxidized to phosphoric acid by air or hydrogen peroxide, followed by the addition of formaldehyde to form hydroxymethylphosphonic acid, which is then further reacted to form Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS).
Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) can be characterized by a range of techniques, including nuclear magnetic resonance spectroscopy (NMR), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR).



ANALYTICAL METHODS OF TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
Several analytical methods have been developed for the detection and quantification of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS), including high-performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC-MS), ion chromatography (IC), and capillary electrophoresis.
These methods offer high accuracy, precision, and sensitivity for the determination of Tetrakis Hydroxymethyl Phosphonium Sulfate (THPS) in various samples, including water, soil, and sediment.



PHYSICAL and CHEMICAL PROPERTIES of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
CAS Number: 55566-30-8
Molecular Weight: 406.28
Beilstein: 8521357
MDL number: MFCD23102118
Molecular Weight: 406.28 g/mol
Hydrogen Bond Donor Count: 8
Hydrogen Bond Acceptor Count: 12
Rotatable Bond Count: 8
Exact Mass: 406.04637137 g/mol
Monoisotopic Mass: 406.04637137 g/mol
Topological Polar Surface Area: 251Ų
Heavy Atom Count: 23
Formal Charge: 0
Complexity: 118
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Physical state: liquid
Color: No data available
Odor: No data available

Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point. No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Melting Point: -31 °F
UNII: 5I8RSL9E6S

Related CAS: 124-64-1 (Parent)
Color/Form: Crystalline solid
Boiling Point: 232 °F at 760 mm Hg
Flash Point: greater than 200 °F
Density: 1.381 at 72 °F
LogP: log Kow = -20.39 (est)
Chemical formula: (HOCH2)4PCl
Molar mass: 190.56 g·mol−1
Appearance: crystalline
Density: 1.341 g/cm3
Melting point: 150 °C (302 °F; 423 K)
Melting point: -35°C
Boiling point: 111°C
Density: 1.4 g/mL at 25 °C(lit.)
vapor pressure: 0 Pa at 20℃
Flash point: 96 °C
storage temp.: Sealed in dry,Room Temperature
form: liquid
Specific Gravity: 1.42
color: Colorless to Almost colorless
Water Solubility: >=10 g/100 mL at 18 ºC
BRN: 8521357
LogP: -9.8

Molecular Weight： 252.18000
Exact Mass： 252.00700
EC Number： 259-709-0
UNII： 5I8RSL9E6S
DSSTox ID： DTXSID0021331
Color/Form： Crystalline solid
HScode： 2931900090
PSA： 180.32000
XLogP3： -1.11140
Appearance： Tetrakis(hydroxymethyl)phosphonium sulfate is a clear colorless viscous liquid.
Density： 1.41 g/cm3 @ Temp: 20 °C
Melting Point： -35ºC
Boiling Point： 111ºC
Flash Point： 96ºC
Water Solubility： In water, 1X10+6 mg/L /miscible/ at 25 deg C (est)
Storage Conditions： Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure： 8.12 mm Hg at 25 deg C (est)
Henrys Law Constant： Henry's Law constant = 1.7X10-23 atm-cu m/mol at 25 °C (est)
Formula: C8H24O12P2S.
Formula Mass: 406.27
MP: -35.0 °C
BP: 111 °C
VP: 32 mm Hg
Density: 1.381 g/cu cm at 20 °C
Hydroxyl radical reaction rate constant = 2.73X10-11 cu cm/molecule-sec at 25 °C (est)
Air and Water Reactions： Water soluble.
Reactive Group： Quaternary Ammonium and Phosphonium Salts



FIRST AID MEASURES of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of TETRAKIS HYDROXYMETHYL PHOSPHONIUM SULFATE (THPS):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Tetrakis(hydroxymethyl)phosphonium sulfate
Bis[tetrakis(hydroxymethyl)phosphonium] sulfate solution
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE
55566-30-8
THPS
Octakis(hydroxymethyl)phosphonium sulfate
TETRAKIS(HYDROXYMETHYL) PHOSPHONIUM SULFATE
5I8RSL9E6S
Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt)
tetrakis(hydroxymethyl)phosphanium
DTXSID0021331
bis[tetrakis(hydroxymethyl)phosphonium] sulfate
Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1)
Retardol S
Pyroset TKO
CCRIS 316
HSDB 4215
NCI-C55050
EINECS 259-709-0
UNII-5I8RSL9E6S
Tetrakis(hydroxymethyl)phosphonium sulphate(2:1)
tetrakis (hydroxymethyl) phosphonium sulfate
EC 259-709-0
SCHEMBL195676
DTXCID001331
CHEMBL1549844
YIEDHPBKGZGLIK-UHFFFAOYSA-L
Tox21_200928
AKOS016010449
Tetrakis(hydroxymethyl)phosphoniumsulfate
NCGC00091951-01
NCGC00091951-02
NCGC00258482-01
CAS-55566-30-8
FT-0659692
T1089
J-519902
Q27262300
TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE [HSDB]
Bis[tetrakis(hydroxymethyl)phosphonium] sulfate solution
Octakis (Hydroxymethyl) Diphosphonium Sulfate
THPS
Octakis(hydroxymethyl)diphosphonium sulfate
Tetrakis(hydroxymethyl) phosphonium sulfate
tetrakis (hydroxymethyl) phosphonium sulfate (2:1)
THPS
thps
BIS[TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM] SULFATE
pyrosettko
nci-c55050
Retardol S
Ncgc00091951-01
HISHICOLIN THPS
THPS (Tech Grade)
Phosphonium Sulfate
Tetrakis(hydroxymethyl)phospho
Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt)
Octakis(hydroxymethyl)phosphonium sulfate
Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1) (salt)
Pyroset TKO
THPS
Retardol S
Tetrakis(hydroxymethyl)phosphonium chloride
Tetrahydroxymethylphosphonium chloride
THPC
Phosphonium,tetrakis(hydroxymethyl)-,sulfate (2:1)
Phosphonium,tetrakis(hydroxymethyl)-,sulfate (2:1) (salt)
Tetrakis(hydroxymethyl)phosphonium sulfate
Pyroset TKO
THPS
Octakis(hydroxymethyl)diphosphonium sulfate
THPS 75
Bis[tetrakis(hydroxymethyl)phosphonium] sulfate
Retardol S
Proban NX
Tolcide PS
Tolcide PS 75
Tolcide PS 200
Tolcide
Magnacide 575
Bis[tetra(hydroxymethyl)phosphonium] sulfate
Aqucar THPS 75
Pyroset TKOW
Tolcide 20A
Tolcide 70A
Eccoshield FR 10
Bricorr 75
Odycide B 320
58591-11-0
65257-04-7
1497435-72-9

Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is an organophosphorus compound.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is used as a precursor in the flame retardant manufacturing process, a biocide in water systems, and a tanning agent in the leather industry.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a safe aqueous solution with antimicrobial properties that is significantly less toxic, effective at lower concentrations, and more biodegradable than other traditional biocides.

CAS: 55566-30-8
MF: C8H24O12P2S
MW: 406.28
EINECS: 259-709-0

Synonyms
bis[tetrakis(hydroxymethyl)phosphonium]sulfatesolution;nci-c55050;Tetrakis (Hydroxymethyl) Phosphonium Sulfate, 75% Aqueous;Bis[tetrakis(hydroxymethyl)phosphonium] sulfate - 70-80% in water;octakis(hydroxymethyl)phosphoniumsulfate;Phosphonium,tetrakis(hydroxymethyl)-,sulfate(2:1)(salt);pyrosettko;tetrakis(hydroxymethyl)-phosphoniusulfate(2:1);TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE;55566-30-8;THPS;Octakis(hydroxymethyl)phosphonium sulfate;TETRAKIS(HYDROXYMETHYL) PHOSPHONIUM SULFATE;5I8RSL9E6S;Bis(tetrakis(hydroxymethyl)phosphonium)sulfate (salt);tetrakis(hydroxymethyl)phosphanium;sulfate;DTXSID0021331;bis[tetrakis(hydroxymethyl)phosphonium] sulfate;Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1);Retardol S;Pyroset TKO;CCRIS 316;HSDB 4215;NCI-C55050;EINECS 259-709-0;UNII-5I8RSL9E6S;Tetrakis(hydroxymethyl)phosphonium sulphate(2:1);tetrakis (hydroxymethyl) phosphonium sulfate;EC 259-709-0;SCHEMBL195676;DTXCID001331;CHEMBL1549844;YIEDHPBKGZGLIK-UHFFFAOYSA-L;Tox21_200928;AKOS016010449;Tetrakis(hydroxymethyl)phosphoniumsulfate;NCGC00091951-01;NCGC00091951-02;NCGC00258482-01;CAS-55566-30-8;FT-0659692;NS00075864;T1089;J-519902;Q27262300;TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM SULFATE [HSDB]

Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a safe aqueous solution with antimicrobial properties that is significantly less toxic, effective at lower concentrations, and more biodegradable than other traditional biocides.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a cationic surfactant that is used in wastewater treatment.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a stable complex with ethylene diamine, which reacts with inorganic acid and sodium carbonate to form a precipitate.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) also has biocidal properties, as it can be used for the disinfection of water.
The chemical reaction mechanism of Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is not yet fully understood, but it has been shown to be carcinogenic in animal studies.

Molybdenum ions are required for the formation of Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) complexes, which may be due to the electrochemical impedance spectroscopy studies that show an increase in the concentration of molybden.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a green quaternary phosphate fungicide, the product is water-soluble, low freezing point, stable chemical properties, and long time storage does not affect its quality.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a new, excellent, efficient, broad-spectrum, low toxicity, low dose, low foaming, environmentally friendly fungicide, has strong killing performance to bacteria and algae.

Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) Chemical Properties
Melting point: -35°C
Boiling point: 111°C
Density: 1.4 g/mL at 25 °C(lit.)
Vapor pressure: 0Pa at 20℃
Fp: 96 °C
Storage temp.: Sealed in dry,Room Temperature
Form: liquid
Specific Gravity: 1.42
Color: Colorless to Almost colorless
Water Solubility: >=10 g/100 mL at 18 ºC
BRN: 8521357
InChI: InChI=1S/C4H12O4P.H2O4S/c5-1-9(2-6,3-7)4-8;1-5(2,3)4/h5-8H,1-4H2;(H2,1,2,3,4)/q+1;/p-1
InChIKey: HFDZMBPIARIWLN-UHFFFAOYSA-M
LogP: -9.8
CAS DataBase Reference: 55566-30-8(CAS DataBase Reference)
EPA Substance Registry System: Tetrakis(hydroxymethyl)phosphonium sulfate (55566-30-8)
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is an organophosphorus compound.

Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a green environmentally friendly quaternary phosphocide fungicide.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS)'s product has good water solubility, low freezing point and stable chemical properties.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is a new type, high efficiency and broad spectrum. Low toxicity, low dose, low foaming, environmentally friendly fungicide.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is also a permanent flame retardant for pure cotton and polyester/cotton fabrics.
Because of its chemical structure, Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) has an active methylol group, and its reaction performance is active.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) can form high polymers with many substances such as amines and phenols.

Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) is widely used as fungicide, microbiological insecticide and scale inhibitor in seabed oil exploitation.
As an odourproof insecticide for landfill.
Kill the harmful substances in garbage, reduce the generation of garbage odor.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) can be used in aquaculture industry such as fish and shrimp farming, as a bottom-water improver, in addition to odor, water purification and a large number of use.
Improve fish and shrimp survival rate.
Tetrakis(Hydroxymethyl)Phosphonium Sulfate (THPS) can be used in the field of anti-corrosion, such as wood products.

Applications
-precursors in flame retardant manufacture process
-biocide in water system
-Tanning agent in the leather industry

Advantage of the wet white tanned leathers, using THPS offers:
-a light color and pastel shades
-They can reach shrink temperatures of at least 70 grad C
-High softness
-Good lightness
-Feeling of naturalness
-Pleasant to the touch
-Beauty that lasts for a long time
-Can be burned without the risk of hexavalent chromium formation

THPC; Tetramethylolphosphonium chloride; Proban CC; Tetrakis(hydroxymethyl)phosphochloride; etrakis(hydroxymethyl)phosphonium chloride CAS NO: 124-64-1

Tetrahydroxymethylphosphonium chloride; THPC; Proban CC; Tetrakis(hydroxymethyl)phosphochloride; etrakis(hydroxymethyl)phosphonium chloride; CAS NO:124-64-1

Tetrahydroxymethylphosphonium chloride; THPC; Proban CC; Tetrakis(hydroxymethyl)phosphochloride; etrakis(hydroxymethyl)phosphonium chloride; CAS NO:124-64-1

THPS; Tetrakis(hydroxymethyl)phosphonium sulfate; Octakis(hydroxymethyl)diphosphonium sulfate; ; Pyroset TKO; Retardol S; Tetrakis(hydroxymethyl)phosphonium sulfate (2:1); Bis(tetrakis(hydroxymethyl)phosphonium)sulfate CAS NO:55566-30-8 CAS NO:58591-11-0 CAS NO:65257-04-7

Tetrakis(hydroxymethyl)phosphonium Sulphate; THPS; Pyroset TKO; Retardol S; Octakis(hydroxymethyl)diphosphonium sulfate; Tetrakis(hydroxymethyl)phosphonium sulfate (2:1); Bis(tetrakis(hydroxymethyl)phosphonium)sulfate CAS NO: 55566-30-8

Tetralin (1,2,3,4-tetrahydronaphthalene) is a hydrocarbon having the chemical formula C10H12.
Tetralin is a partially hydrogenated derivative of naphthalene.
Tetralin is a colorless liquid that is used as a hydrogen-donor solvent.

CAS Number: 119-64-2
Molecular Formula: C10H12
Molecular Weight: 132.20

Tetralin appears as a light colored liquid.
May be irritating to skin, eyes and mucous membranes.

Tetralin is an ortho-fused bicyclic hydrocarbon that is 1,2,3,4-tetrahydro derivative of naphthalene.
Tetralin is an ortho-fused bicyclic hydrocarbon and a member of tetralins.
Tetralin derives from a hydride of a naphthalene.

Tetralin is a potent antagonist of bacterial fatty acid synthase, which is the key enzyme in the biosynthesis of fatty acids.
Tetralin has also been shown to be an antihypertensive compound with a kinetic mechanism that is not yet understood.

The chemical reactions involved in the synthesis of tetralin are most likely due to Tetralin chiral nature.
Tetralin can also be synthesized by asymmetric synthesis using a surface methodology.
Tetralin has been shown to have no carcinogenic effects in rodent studies.

Tetralin (1,2,3,4-tetrahydronaphthalene) is a hydrocarbon having the chemical formula C10H12.
This molecule is similar to the naphthalene chemical structure except that one ring is saturated.

The compound can be synthesized in a Bergman cyclization.
In a classic named reaction called the Darzens tetralin synthesis derivatives can be prepared by intramolecular ring-closing reaction of an 1-aryl-4-pentene with concentrated sulfuric acid or simply through the hydrogenation of naphthalene in the presence of a platinum catalyst.

Tetralin is used as a solvent.
Tetralin is also used for the laboratory synthesis of dry HBr gas.

Tetralin is a potent antagonist of bacterial fatty acid synthase, which is the key enzyme in the biosynthesis of fatty acids.
Tetralin has been shown to be effective against wild-type strains and mutant strains of Escherichia coli, Salmonella typhimurium, and Staphylococcus aureus.

Tetralin has also been shown to be an antihypertensive compound with a kinetic mechanism that is not yet understood.
The chemical reactions involved in the synthesis of tetralin are most likely due to Tetralin chiral nature.

Tetralin can also be synthesized by asymmetric synthesis using a surface methodology.
Tetralin has been shown to have no carcinogenic effects in rodent studies.

Tetralin and benzodioxans:
Tetralin (TET), 1,4-benzodioxan (14BZD), and 1,3-benzodioxan (13BZN) are all analogous to the cyclohexene family of molecules and hence have twisted structures with high barriers to planarity.
Because of their low vapor pressures, they have not been studied by far-infrared spectroscopy, but their S0 vibrational data have been obtained using SVLF spectra of the jet-cooled molecules and high-temperature vapor-phase Raman spectra.

Uses of Tetralin:
Tetralin is used as a hydrogen-donor solvent, for example in coal liquifaction.
Tetralin functions as a source of H2, which is transferred to the coal.
The partially hydrogenated coal is more soluble.

Tetralin has been used in sodium-cooled fast reactors as a secondary coolant to keep sodium seals around pump impellers solidified.
However Tetralin use has been superseded by NaK.

Tetralin is also used for the laboratory synthesis of HBr:
C10H12 + 4 Br2 → C10H8Br4 + 4 HBr

The facility of this reaction is in part a consequence of the moderated strength of the benzylic C-H bonds.

Tetralin is used in solvent, paint, varnish and rubber industry; Tetralin is used in shoe polish and floor polish.
Solvent for camphor, sulfur and iodine; in paint thinners; as a paint remover when mixed with decalin or white spirit; Used as an insecticide for clothes moth.

Mothballs used as a substitute for turpentine in polishes, shoe polishes, floor polishes, solvent for fats, resins, oils, waxes; Used as degreasing agent.
In plant pathology, tetralin has been successful in the complete eradication of crown gall and olive leg neoplasms.
The combination of 31% tetrahydronaphthalene and 0.03% cupric oleate (cuprex) is advertised as a pediculicide and miticide, but Tetralin true effectiveness has yet to be determined.

Industry Uses:
Heat transferring agent

Consumer Uses:
Solvent

Industrial Processes at risk of exposure:
Painting (Solvents)

General Manufacturing Information of Tetralin:
Industry Processing Sectors
All Other Basic Organic Chemical Manufacturing

Production of Tetralin:
Tetralin is produced by the catalytic hydrogenation of naphthalene.

Although nickel catalysts are traditionally employed, many variations have been evaluated.
Over-hydrogenation converts tetralin into decahydronaphthalene (decalin).
Rarely encountered is dihydronaphthalene (dialin).

Laboratory methods of Tetralin:
In a classic named reaction called the Darzens tetralin synthesis, named for Auguste Georges Darzens (1926), derivatives can be prepared by intramolecular electrophilic aromatic substitution reaction of a 1-aryl-4-pentene using concentrated sulfuric acid.

Handling and Storage of Tetralin:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling the product must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Tetralin without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers.
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Safe Storage:
Separated from strong oxidants.
Keep in a well-ventilated room.
Well closed.

Storage Conditions:
In general materials toxic as stored or which can decomp into toxic components should be stored in cool ventilated place, out of sun, away from fire hazard be periodically inspected and monitored.
Incompatible materials should be isolated.

First Aid Measures of Tetralin:

INGESTION:
Induce vomiting.
Call a doctor.
Medical treatment should be aimed at conservation of liver and kidney function.

EYES:
Flush with water for at least 15 min.
Call a doctor.

SKIN:
Wipe off, wash with soap and water.

Fire Fighting of Tetralin:
The majority of these products have a very low flash point.
Use of water spray when fighting fire may be inefficient.

For mixtures containing alcohol or polar solvent, alcohol-resistant foam may be more effective.

SMALL FIRE:
Dry chemical, CO2, water spray or regular foam.

LARGE FIRE:
Water spray, fog or regular foam.
Avoid aiming straight or solid streams directly onto the product.
If Tetralin can be done safely, move undamaged containers away from the area around the fire.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned master stream devices or monitor nozzles.

Cool containers with flooding quantities of water until well after fire is out.
For petroleum crude oil, do not spray water directly into a breached tank car.

This can lead to a dangerous boil over.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

ALWAYS stay away from tanks engulfed in fire.
For massive fire, use unmanned master stream devices or monitor nozzles.
If this is impossible, withdraw from area and let fire burn.

Identifiers of Tetralin:
CAS Number: 119-64-2
ChEBI: CHEBI:35008
ChemSpider: 8097
ECHA InfoCard: 100.003.946
KEGG: C14114
PubChem CID: 8404
UNII: FT6XMI58YQ
CompTox Dashboard (EPA): DTXSID1026118
InChI:
InChI=1S/C10H12/c1-2-6-10-8-4-3-7-9(10)5-1/h1-2,5-6H,3-4,7-8H2
Key: CXWXQJXEFPUFDZ-UHFFFAOYSA-N
InChI=1/C10H12/c1-2-6-10-8-4-3-7-9(10)5-1/h1-2,5-6H,3-4,7-8H2
Key: CXWXQJXEFPUFDZ-UHFFFAOYAG
SMILES: c1ccc2c(c1)CCCC2

CAS Number: 119-64-2
Molecular Formula: C10H12
Molecular Weight: 132.20
IUPAC Name: 1,2,3,4-tetrahydronaphthalene
Other Names: Naphthalene 1,2,3,4-tetrahydride, Bacticin, Benzocyclohexane, THN

Product Code: FT46025
Synonyms: 1,2,3,4-Tetrahydronaphthalene
CAS Number: 119-64-2
Chemical Formula: C10H12
Molecular Weight: 132.20
Appearance: Colourless to pale yellow liquid
Purity (GC): min 95%

CAS No: [119-64-2]
Synonyms: 1,2,3,4-Tetrahydronaphthalene
Product Code: FT46025
MDL No: MFCD00001733
Chemical Formula: C10H12
Molecular Weight: 132.2 g/mol
Smiles: C1CCC2=CC=CC=C2C1
UN Number: UN3082
Pack Group: III
Class: 9

Properties of Tetralin:
Chemical formula: C10H12
Molar mass: 132.206 g·mol−1
Appearance: colorless liquid with an odor similar to naphthalene
Density: 0.970 g/cm3
Melting point: −35.8 °C (−32.4 °F; 237.3 K)
Boiling point: 206 to 208 °C (403 to 406 °F; 479 to 481 K)
Solubility in water: Insoluble
Viscosity: 2.02 cP at 25 °C[1]

Molecular Formula: C10H12
Molar Mass: 132.2
Density: 0.973 g/mL at 25 °C (lit.)
Melting Point: -35 °C (lit.)
Boling Point: 207 °C (lit.)
Flash Point: 171°F
Water Solubility: INSOLUBLE
Solubility: 0.045g/l
Vapor Presure: 0.18 mm Hg ( 20 °C)
Vapor Density: 4.55 (vs air)
Appearance: Fluid
Color: Colorless
Merck: 14,9221
BRN: 1446407
Storage Condition: Store below +30°C.
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Sensitive: Air Sensitive
Explosive Limit: 0.8%, 100°F
Refractive Index: n20/D 1.541(lit.)

Molecular Weight: 132.20
XLogP3: 3.5
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 0
Exact Mass: 132.093900383
Monoisotopic Mass: 132.093900383
Topological Polar Surface Area: 0 Ų
Heavy Atom Count: 10
Complexity: 92.6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Tetralin:
Appearance (Clarity): Clear
Appearance (Colour): Colourless
Appearance (Form): Liquid
Assay (GC): min. 98%
Density (g/ml) @ 20°C: 0.968-0.970
Refractive Index (20°C): 1.540-1.542
Boiling Range: 204-207°C
Water (KF): max. 0.1%

Names of Tetralin:

CAS names:
Naphthalene
1,2,3,4-tetrahydro-

Regulatory process name:
1,2,3,4-tetrahydronaphthalene

Translated names:
1,2,3,4-tetrahidronaftalen (hr)
1,2,3,4-tetrahidronaftalen (sl)
1,2,3,4-tetrahidronaftalenas (lt)
1,2,3,4-tetrahidronaftaleno (es)
1,2,3,4-tetrahidronaftaleno (pt)
1,2,3,4-tetrahidronaftalin (hu)
1,2,3,4-tetrahidronaftalina (ro)
1,2,3,4-tetrahidronaftalīns (lv)
1,2,3,4-tetrahydronaftaleen (nl)
1,2,3,4-tetrahydronaftaleeni (fi)
1,2,3,4-tetrahydronaftalen (cs)
1,2,3,4-tetrahydronaftalen (no)
1,2,3,4-tetrahydronaftalen (pl)
1,2,3,4-tetrahydronaftalen (sv)
1,2,3,4-tetrahydronaftalén (sk)
1,2,3,4-tetrahydronaphtalen (da)
1,2,3,4-Tetrahydronaphthalin (de)
1,2,3,4-Tetrahüdronaftaleen (et)
1,2,3,4-tetraidronaftalene (it)
1,2,3,4-tétrahydronaphtalène (fr)
1,2,3,4-τετραϋδροναφθαλένιο (el)
1,2,3,4-тeтрахидронафталeн (bg)
tetralina (pl)

Trade names:
tetralinova frakce
tetralín

IUPAC names:
1,2,3,4-tetrahydronaphthalene
1,2,3,4-tetrahydronaphtalene
1,2,3,4-Tetrahydronaphthalene
1,2,3,4-tetrahydronaphthalene
1,2,3,4-tetrahydronaphthalene
1,2,3,4-Tetrahydronaphthalin
Tetrahydronaphthalene

Preferred IUPAC name:
1,2,3,4-Tetrahydronaphthalene

Other names:
1,2,3,4-Tetrahydronaphthalene
Benzocyclohexane
NSC 77451
Tetrahydronaphthalene
Tetranap

Other identifiers:
119-64-2
601-045-00-4

Synonyms of Tetralin:
1,2,3,4-Tetrahydronaphthalene
TETRALIN
119-64-2
Benzocyclohexane
Tetrahydronaphthalene
Bacticin
Tetraline
Tetranap
Naphthalene, 1,2,3,4-tetrahydro-
Tetralina
Naphthalene, tetrahydro-
Naphthalene 1,2,3,4-tetrahydride
tetralene
NSC 77451
FT6XMI58YQ
CHEBI:35008
1,2,3,4-tetrahydro-naphthalene
NSC-77451
68412-24-8
Tetralina [Polish]
Caswell No. 842A
CAS-119-64-2
CCRIS 3564
HSDB 127
delta(sup 5,7,9)-naphthantriene
EINECS 204-340-2
UNII-FT6XMI58YQ
1,2,3,4-Tetrahydronaphthalene, reagent grade, >=97%
EPA Pesticide Chemical Code 055901
AI3-01257
Tetralin solvent
EINECS 270-178-4
MFCD00001733
TETRALIN [HSDB]
TETRALIN [MI]
bmse000530
TETRALIN [USP-RS]
TETRALIN [WHO-DD]
EC 204-340-2
NCIOpen2_000650
1,3,4-Tetrahydronaphthalene
1,2,3,4-tetrahydronapthalene
5,6,7,8-tetrahydronaphthalene
CHEMBL1575635
DTXSID1026118
Naphthalene 1,3,4-tetrahydride
WLN: L66 & TJ
1,2,3,4 Tetrahyclronaphthalene
.delta.(5,7,9)-Naphthantriene
.delta.(sup 5,9)-Naphthantriene
Naphthalene-1,2,3,4-tetrahydride
NSC77451
ZINC8437660
Tox21_201793
Tox21_303325
STL264224
.delta.(sup 5,7,9)-Naphthantriene
AKOS000121383
NCGC00091744-01
NCGC00091744-02
NCGC00256948-01
NCGC00259342-01
FT-0654145
T0107
T0713
EN300-21134
1,2,3,4-tetrahydronaphthalene, Tetralin, THN
1,2,3,4-Tetrahydronaphthalene, anhydrous, 99%
Q420416
1,2,3,4-Tetrahydronaphthalene, analytical standard
W-108503
1,2,3,4-Tetrahydronaphthalene, ReagentPlus(R), 99%
F1908-0164
1,2,3,4-Tetrahydronaphthalene, Vetec(TM) reagent grade, 98%
1,2,3,4-Tétrahydronaphtalène [French] [ACD/IUPAC Name]
1,2,3,4-Tetrahydronaphthalen
1,2,3,4-Tetrahydronaphthalene [ACD/IUPAC Name]
1,2,3,4-Tetrahydronaphthalin [German] [ACD/IUPAC Name]
119-64-2 [RN]
1446407 [Beilstein]
204-340-2 [EINECS]
FT6XMI58YQ
MFCD00001733 [MDL number]
Naphthalene, 1,2,3,4-tetrahydro- [ACD/Index Name]
tetrahydronaphthalene
Tetralin [Wiki]
Tetralin(R) solvent
Tetralina [Polish]
Tetraline [Dutch]
Tétraline [French]
[119-64-2] [RN]
1,2,3, 4-Tetrahydronaphthalene
1,2,3,4-Tetrahydronaphthalene 10 µg/mL in Methanol
1,2,3,4-tetrahydronaphthalene(tetralin)
1,2,3,4-tetrahydronaphthalene, Tetralin, THN
1,2,3,4-Tetrahydronaphthalene;Tetralin
1,2,3,4-TETRHYDRONAPHTHALENE
204-340-2MFCD00001733
270-178-4 [EINECS]
68412-24-8 [RN]
benzocyclohexane
C095210
EINECS 204-340-2
EINECS 270-178-4
naphthalene 1,2,3,4-tetrahydride
NAPHTHALENE, TETRAHYDRO-
Naphthalene-1,2,3,4-tetrahydride
pWLN: L66 & TJ
teteralin
tetralene
Tetralin(TM) solvent
Tetralin?
Tetralina
Tetralina [Polish]
Tetraline
Tetrana
TETRANAP
THN
UNII:FT6XMI58YQ
UNII-FT6XMI58YQ
WLN: L66 & TJ
δ(5,7,9)-Naphthantriene
δ(sup 5,7,9)-naphthantriene
δ(sup 5,7,9)-Naphthantriene

An ortho-fused bicyclic hydrocarbon that is Tetralin derivative of naphthalene.
Tetralin or 1,2,3,4-tetrahydronaphthalene is a flammable liquid.
As a solvent for fats and oils and as an alternative to turpentine in polishes and paint; insecticide.

CAS: 119-64-2
MF: C10H12
MW: 132.2
EINECS: 204-340-2

A light colored liquid.
May be irritating to skin, eyes and mucous membranes.
Flash point 100-141°F.
Tetralin is a hydrocarbon having the chemical formula C10H12.
Tetralin is a partially hydrogenated derivative of naphthalene.
Tetralin is a colorless liquid that is used as a hydrogen-donor solvent.
Tetralin is an organic compound, a hydrocarbon having the chemical formula C10H12.
Tetralin is similar to naphthalene in structure, except one ring is saturated.

Tetralin is a potent antagonist of bacterial fatty acid synthase, which is the key enzyme in the biosynthesis of fatty acids.
Tetralin has been shown to be effective against wild-type strains and mutant strains of Escherichia coli, Salmonella typhimurium, and Staphylococcus aureus.
Tetralin has also been shown to be an antihypertensive compound with a kinetic mechanism that is not yet understood.
Tetralin reactions involved in the synthesis of tetralin are most likely due to its chiral nature.
Tetralin can also be synthesized by asymmetric synthesis using a surface methodology.
Tetralin has been shown to have no carcinogenic effects in rodent studies.

Tetralin Chemical Properties
Melting point: -35 °C (lit.)
Boiling point: 207 °C (lit.)
Density: 0.973 g/mL at 25 °C (lit.)
Vapor density: 4.55 (vs air)
Vapor pressure: 0.18 mm Hg ( 20 °C)
Refractive index: n20/D 1.541(lit.)
Fp: 171 °F
Storage temp.: Store below +30°C.
Solubility: 0.045g/l
Form: Fluid
Color: Colorless
Odor: pungent menthol odor
Odor Threshol: 0.0093ppm
Explosive limit: 0.8%, 100°F
Water Solubility: INSOLUBLE
Sensitive: Air Sensitive
Merck: 14,9221
BRN: 1446407
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 3.78 at 23℃
CAS DataBase Reference: 119-64-2(CAS DataBase Reference)
NIST Chemistry Reference: Tetralin(119-64-2)
EPA Substance Registry System: Tetralin (119-64-2)

Uses
Tetralin, is used as an intermediate for organic synthesis, solvent.
Tetralin is used as a solvent.
Tetralin is also used for the laboratory synthesis of dry HBr gas.
Solvent for naphthalene, fats, resins, oils, waxes, used instead of turpentine in lacquers, shoe polishes, floor waxes.

Uses
Tetralin is used as a hydrogen-donor solvent, for example in coal liquifaction.
Tetralin functions as a source of H2, which is transferred to the coal.
The partially hydrogenated coal is more soluble.
Tetralin has been used in sodium-cooled fast reactors as a secondary coolant to keep sodium seals around pump impellers solidified; however its use has been superseded by NaK.: 24:30 
Tetralin is also used for the laboratory synthesis of hydrogen bromide:

C10H12 + 4 Br2 → C10H8Br4 + 4 HBr
The facility of this reaction is in part a consequence of the moderated strength of the benzylic C-H bonds.

A large number of used in the manufacture of insecticide carbaryl intermediate cresol; Also used in the manufacture of lubricants, and used to reduce the viscosity of high viscosity oil, and widely used as organic (resin, wax, grease, paint, plastic, etc.) of the solvent.
Tetralin can also be used in the gas industry to dissolve, remove naphthalene deposition in the equipment, and as a liquid for washing gas.
Tetralin is mixed with alcohol and benzene as a fuel for internal combustion engines.
In addition, Tetralin can be used as a degreasing agent, a softener, an absorbent of low boiling point organic compound vapor, an insect repellent and a substitute for turpentine.

Production Methods
Tetralin is prepared by the catalytic hydrogenation of naphthalene or during acidic, catalytic hydrocracking of phenanthrene.
At 700℃, tetralin yields tars that contain appreciable quantities of 3,4-benzopyrene (172a).

Reactivity Profile
Tetralin may react vigorously with strong oxidizing agents.
May react exothermically with reducing agents to release hydrogen gas.
Oxidizes readily in air to form unstable peroxides that may explode spontaneously.

Health Hazard
Liquid may cause nervous disturbance, green coloration of urine, and skin and eye irritation.

Carcinogenicity
In male and female F344/N and NBR rats exposed to tetralin at concentrations of 0, 30, 60, or 120 ppm, 6 h plus T90 (12 min) per day, 5 days per week for 105 weeks, there were slightly increased incidences of cortical renal tubule adenoma in male rats.
The incidence of cortical renal tubule adenomawas also significantly increased in the 120 ppm group.
Exposure of male and female B6C3F1 mice to tetralin at concentrations of 0, 30, 60, or 120 ppm, 6 h plus T90 (12 min) per day, 5 days per week for 105 weeks and additional groups of male and female mice to the same concentrations for 12 months led to increased incidence of hemangiosarcoma of the spleen in 120 ppm females (172b).

Purification Methods
Wash tetralin with successive portions of conc H2SO4 until the acid layer is no longer coloured, then wash it with aqueous 10% Na2CO3, and then distilled water.
Dry (CaSO4 or Na2SO4), filter, reflux and fractionally distil it under under reduced pressure from sodium or BaO.
Tetralin can also be purified by repeated fractional freezing.
Bass freed tetralin, purified as above, from naphthalene and other impurities by conversion to ammonium tetralin-6-sulfonate.
Concentrated H2SO4 (150mL) is added slowly to stirred tetralin (272mL) which is then heated on a water bath for about 2hours for complete solution.

The warm mixture, when poured into aqueous NH4Cl solution (120g in 400mL water), gives a white precipitate which, after filtering off, is crystallised from boiling water, washed with 50% aqueous EtOH and dried at 100o.
Evaporation of its boiling aqueous solution on a steam bath removes traces of naphthalene.
The pure salt (229g) is mixed with conc H2SO4 (266mL) and steam distilled from an oil bath at 165-170o.
An ether extract of the distillate is washed with aqueous Na2SO4, and the ether is evaporated, prior to distilling the tetralin from sodium.
Tetralin has also been purified via barium tetralin-6-sulfonate, conversion to the sodium salt and decomposed in 60% H2SO4 using superheated steam.

Synonyms
1,2,3,4-Tetrahydronaphthalene
TETRALIN
119-64-2
Benzocyclohexane
Tetrahydronaphthalene
Bacticin
Tetraline
Tetranap
Tetralina
Naphthalene, 1,2,3,4-tetrahydro-
Naphthalene, tetrahydro-
Naphthalene 1,2,3,4-tetrahydride
tetralene
Tetralina [Polish]
Caswell No. 842A
NSC 77451
CCRIS 3564
HSDB 127
delta(sup 5,7,9)-naphthantriene
EINECS 204-340-2
UNII-FT6XMI58YQ
FT6XMI58YQ
EPA Pesticide Chemical Code 055901
AI3-01257
DTXSID1026118
CHEBI:35008
1,2,3,4-tetrahydro-naphthalene
EINECS 270-178-4
NSC-77451
EC 204-340-2
68412-24-8
DTXCID306118
CAS-119-64-2
1,2,3,4-Tetrahydronaphthalene, reagent grade, >=97%
Tetralin solvent
Ttrahydronaphtalne
tetrahydronapthalene
MFCD00001733
THN (CHRIS Code)
TETRALIN [HSDB]
TETRALIN [MI]
bmse000530
TETRALIN [USP-RS]
TETRALIN [WHO-DD]
NCIOpen2_000650
1,3,4-Tetrahydronaphthalene
1,2,3,4-tetrahydronapthalene
5,6,7,8-tetrahydronaphthalene
CHEMBL1575635
Naphthalene 1,3,4-tetrahydride
WLN: L66 & TJ
1,2,3,4 Tetrahyclronaphthalene
.delta.(5,7,9)-Naphthantriene
.delta.(sup 5,9)-Naphthantriene
Naftaleno, 1,2,3,4-tetrahidro-
Naphthalene-1,2,3,4-tetrahydride
NSC77451
Tox21_201793
Tox21_303325
LS-620
STL264224
.delta.(sup 5,7,9)-Naphthantriene
AKOS000121383
NCGC00091744-01
NCGC00091744-02
NCGC00256948-01
NCGC00259342-01
TETRAHYDRONAPHTHALENE, 1,2,3,4-
FT-0654145
T0107
T0713
EN300-21134
Tetrahydronaphthalene , 1,2,3,4- (tetralin)
1,2,3,4-Tetrahydronaphthalene, anhydrous, 99%
Q420416
TETRALIN (SEE ALSO DECALIN (91-17-8))
1,2,3,4-Tetrahydronaphthalene, analytical standard
W-108503
1,2,3,4-Tetrahydronaphthalene, ReagentPlus(R), 99%
F1908-0164
1,2,3,4-Tetrahydronaphthalene, Vetec(TM) reagent grade, 98%
InChI=1/C10H12/c1-2-6-10-8-4-3-7-9(10)5-1/h1-2,5-6H,3-4,7-8H

Tetrameen OV is an oleyl (vegetable oil) tripropylenetetraamine.
Tetrameen OV's functions include corrosion inhibitor, dispersing agent, emulsifier, and hydrophobizing.


CAS Number: 349636-04-0
Chemical Name: Oleyl (Vegetable Oil) Tripropylene Tetraamine
Molecular Formula : C6H16N2


Tetrameen OV appears as a water-white colored liquid with a fishlike odor.
The flash point of Tetrameen OV is 68°F.
Tetrameen OV is less dense than water.


Tetrameen OV's Vapors are heavier than air.
Tetrameen OV is a colorless to slightly yellow liquid.
Tetrameen OV is an ethylenediamine derivative in which each nitrogen carries two methyl substituents.


Tetrameen OV is an oleyl (vegetable oil) tripropylenetetraamine.
Tetrameen OV's functions include corrosion inhibitor, dispersing agent, emulsifier, and hydrophobizing.
Tetrameen OV appears as a water-white-colored liquid with a fishlike odor.


Tetrameen OV is an ethylenediamine derivative in which each nitrogen carries two methyl substituents.
Tetrameen OV appears as a water-white colored liquid with a fishlike odor.
Tetrameen OV is a molecule that allows rapid polymerization of polyacrylamide gels.


In the presence of ammonium persulfate, Tetrameen OV is responsible for the formation of free radicals from persulfate, thereby initiating the acrylamide polymerization process.
However, excess concentration of Tetrameen OV can result in abnormal separation patterns.


Tetrameen OV is a colorless to slightly yellow liquid
Tetrameen OV is actively involved in the formation of anionic organometallic complex.
Tetrameen OV is an ethylenediamine derivative in which each nitrogen carries two methyl substituents.



USES and APPLICATIONS of TETRAMEEN OV:
Tetrameen OV is ideal for use in automotive polishes and metal cleaning applications.
Tetrameen OV is used for Cleaning.
Tetrameen OV is used Automotive Polishes, Metal cleaning


Applications & Uses of Tetrameen OV: HI&I Care — Home Care, Surface Care, HI&I Care — Institutional & Industrial Care, Vehicle & Machinery
Home Care Applications of Tetrameen OV: Metal Cleaners, I&I Cleaning Applications, and Automotive Polishes
Tetrameen OV is used to make epoxy curing agents, polyurethane, and quaternary ammonium compounds.


Tetrameen OV is also used in textile finishing agents, as a corrosion inhibitor, acrylamide polymerization catalyst, and reagent.
Tetrameen OV is used as polymerization accelerator in gel electrophoresis, a solvent, and an oxidizing reagent
Tetrameen OV is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.


Tetrameen OV is used as anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance.
Tetrameen OV is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis.
Tetrameen OV is widely employed as a ligand for metal ions.


Tetrameen OV can also be a component of Hypergolic propellants. Tetrameen OV is an essential catalyst for polyacrylamide gel polymerization.
Tetrameen OV is frequently used with another catalyst, APS, for the preparation of polyacrylamide gels for protein and nucleic acid analysis.
Tetrameen OV is used to make other chemicals.


Tetrameen OV is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation.
Tetrameen OV has a role as a chelator and a catalyst.
Tetrameen OV is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.


Tetrameen OV is used as anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance.
Tetrameen OV is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis.
Tetrameen OV is widely employed as a ligand for metal ions.


Tetrameen OV can also be a component of Hypergolic propellants.
Tetrameen OV is an essential catalyst for polyacrylamide gel polymerization.
Tetrameen OV is frequently used with another catalyst, APS, for the preparation of polyacrylamide gels for protein and nucleic acid analysis.


Tetrameen OV is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.
Tetrameen OV is used as anti-hyperlipidemic, plant growth stimulator, pathogen growth inhibitor, confers plant disease resistance.
Tetrameen OV is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis.


Tetrameen OV is widely employed as a ligand for metal ions.
Tetrameen OV can also be a component of Hypergolic propellants.
Tetrameen OV is an essential catalyst.


Tetrameen OV is used to catalyze the formation of free radicals from ammonium persulfate or riboflavin.
The free radicals will cause acrylamide and bis-acrylamide to polymerize to form a gel matrix which can be used for sieving macromolecules such as nucleic acids and proteins.


Tetrameen OV has been used in the coating of soft polymers, such as polyacrylamide, in capillaries for investigation by atom force microscopy.
Microchips containing oligonucleotides and proteins immobilized within gel pads have been prepared using Tetrameen OV.
Tetrameen OV is also used in the HPLC of small organic molecules.


Tetrameen OV is used as a Polyacrylamide gel formation catalyst.
Tetrameen OV is used with ammonium persulfate to catalyze the polymerization of acrylamide when making polyacrylamide gels, used in gel electrophoresis, for the separation of proteins or nucleic acids.


Tetrameen OV is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation.
Tetrameen OV is a water-white colored liquid with a fishlike odor.
Tetrameen OV is used to make other chemicals.


Tetrameen OV is used to make other chemicals.
Tetrameen OV is used to make other chemicals.
Tetrameen OV is an ethylenediamine derivative in which each nitrogen carries two methyl substituents.


Tetrameen OV is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation.
Tetrameen OV has a role as a chelator and a catalyst.
Tetrameen OV is slightly soluble in water.


Tetrameen OV is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.
Tetrameen OV is also used for the separation of proteins or nucleic acids.
Further, Tetrameen OV is employed as a ligand for metal ions like zinc and copper.


Tetrameen OV is actively involved in the formation of anionic organometallic complex.
Tetrameen OV is widely employed both as a ligand for metal ions and as a catalyst in organic polymerisation.
Tetrameen OV has a role as a chelator and a catalyst.


Tetrameen OV, also known simply as Tetramethylethylenediamine, used in gel electrophoresis, for the separation of proteins or nucleic acids.
Tetrameen OV has been used for the preparation of acrylamide hydrogels and sodium dodecyl sulfate-polyacrylamide gels.



FUNCTIONS OF TETRAMEEN OV:
*Corrosion Inhibitor
*Dispersing Agent
*Hydrophobizing
*Emulsifier
*Surfactant (Cationic)
*Water Repellent
*Surfactant



TETRAMEEN OV FAMILIES:
-Cleaning Ingredients — Cleaning Aids
*Emulsifiers & Demulsifiers ,
*Wetting & Dispersion Aids
-Cleaning Ingredients — Functional Additives
-Other Functional Additives
*Performance Additives
-Cleaning Ingredients — Soaps & Surfactants
*Cationic Surfactants



REACTIVITY PROFILE OF TETRAMEEN OV:
Tetrameen OV neutralizes acids in exothermic reactions to form salts plus water.
Tetrameen OV may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.



PHYSICAL and CHEMICAL PROPERTIES of TETRAMEEN OV:
Amine number: 460-485 mg KOH/g
Color: ≤ 5 Gardner
Iodine value: ≥ 25 g I₂/100 g
Characteristics: Appearance Solid
Density: 850 kg/m³ at 60ºC
Flash point, Pensky Martens Closed Cup: 170 °C
Melting point: 25-35 °C
Water content: ≤ 0.5%
CAS Min %: 98.5
CAS Max %: 100.0
Melting Point: -55.0°C
Color: Colorless to Yellow
Density: 0.7700g/mL
Boiling Point: 120.0°C to 122.0°C
Flash Point: 17°C
Infrared Spectrum: Authentic
Assay Percent Range: 98.5% min. (GC)
Linear Formula: (CH3)2NCH2CH2N(CH3)2
Refractive Index: 1.4169 to 1.4189
Beilstein: 04, 250
Fieser: 02,403; 03,284; 04,485; 05,652; 06,576;
07,358; 11,340; 12,477; 14,68; 15,63; 16,55
Merck Index: 15, 9277

Specific Gravity: 0.77
Solubility Information: (10% in water) Clear and no haze
Formula Weight: 116.21
Percent Purity: 99%
Grade: Biochemistry
Physical Form: Liquid
Molecular Weight: 116.20 g/mol
XLogP3: 0.3
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 3
Exact Mass: 116.131348519 g/mol
Monoisotopic Mass: 116.131348519 g/mol
Topological Polar Surface Area: 6.5Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 42.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 121 °C (1013 hPa)
Density: 0.78 g/cm3 (20 °C)
Explosion limit: 1 - 9 %(V)
Flash point: 19 °C
Ignition temperature: 145 °C
Melting Point: -55 °C
pH value: 8.0 - 8.5 (0.1 g/l, H₂O, 20 °C)
Vapor pressure: 21 hPa (20 °C)
Molecular Weight： 116.20500
Exact Mass： 116.20
EC Number： 203-744-6
UNII： K90JUB7941
UN Number： 2372
DSSTox ID： DTXSID5026122
Color/Form： Colorless liquid
HScode： 2921219000
Density： 0.7765 g/cm3 @ Temp: 20 °C
Melting Point： -55 °C
Boiling Point： 121 °C
Flash Point： 21ºC
Refractive Index： 1.4169-1.4189
Water Solubility： Micible with water.
Storage Conditions： Store at RT.

Vapor Pressure： 14.9mmHg at 25°C
Vapor Density： 4 (vs air)
Explosive limit： 1-9%(V)
Odor： Slight ammoniacal odor
Experimental: Properties：
Freezing pt: -55.1 °C
Melting point: −55 °C(lit.)
Boiling point: 120-122 °C(lit.)
Density: 0.775 g/mL at 20 °C(lit.)
vapor density: 4 (vs air)
vapor pressure: 21 hPa (20 °C)
refractive index: n20/D 1.4179(lit.)
Flash point: 50 °F
storage temp.: Store below +30°C.
solubility: H2O: 10 mg/mL at 20 °C, clear, colorless
form: Liquid
pka: 10.40, 8.26(at 25℃)
Specific Gravity: 0.777 (20/4℃)
color: Clear colorless to slightly yellow
Odor: Amine like
PH: 8.0-8.5 (0.1g/l, H2O, 20℃)
explosive limit: 1-9%(V)
Water Solubility: miscible
Sensitive: Hygroscopic
Merck: 14,9134
BRN: 1732991
Stability: Stable.
InChIKey: DMQSHEKGGUOYJS-UHFFFAOYSA-N
LogP: -0.13 at 20.2℃



FIRST AID MEASURES of TETRAMEEN OV:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAMEEN OV:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of TETRAMEEN OV:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAMEEN OV:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of TETRAMEEN OV:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of TETRAMEEN OV:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
N,N,N',N'-tetramethylethylenediamine
1,2-di(dimethylamino)ethane
1,2-ethanediamine, N,N,N',N'-tetramethyl-
bis(dimethylamino)ethane
N,N,N',N'-di(dimethylamino)ethane
N,N,N',N'-tetramethyl-1,2-
diaminoethane
N,N,N',N'-tetramethyl-1,2-ethanediamine
N,N,N',N'-tetramethylethenediamine
N,N,N',N'-tetramethylethylenediamine
propamine D
TEMED
tetrameen
tetramethyldiaminoethane
TMEDA
(CH3)2NCH2CH2N(CH3)2
1,2-Bis(dimethylamino)ethane
1,2-Di-(dimethylamino)ethane
1,2-Diaminoethane, N,N,N',N'-tetramethyl-
1,2-Ethanediamine, N1,N1,N2,N2-tetramethyl-
2,5-dimethyl-2,5-diazahexane
Dimethyl[2-(dimethylamino)ethyl]amine
Ethylenediamine, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethyl-1,2-diaminoethane
N,N,N',N'-Tetramethyl-1,2-ethanediamine
N,N,N',N'-Tetramethylethanediamine
N,N,N',N'-Tetramethylethenediamine
N,N,N',N'-Tetramethylethylenediamine
N,N,N1,N1-Tetramethylethylenediamine
Propamine D
TMEDA
Temed
Tetrameen
Tetramethyl ethylene diamine
Tetramethyldiaminoethane
UN 2372
1,2-Bis-(dimethylamino)ethane
1,2-Ethanediamine, N,N,N',N'-tetramethyl-
Dimethyl(2-(dimethylamino)ethyl)amine
Ethylenediamine, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethyl-1,2-diaminoethane
N,N,N',N'-Tetramethylethanediamine
N,N,N',N'-Tetramethylethylenediamine
Propamine D
TMEDA
TEMED
Tetrameen
Tetramethyl ethylene diamine
Tetramethyldiaminoethane
Tetramethylethylenediamin
1,2-Di-(dimethylamino)ethane
UN2372
N,N,N',N'-Tetramethylethylenediamine
110-18-9
Temed
TMEDA
Tetramethylethylenediamine
N,N,N',N'-tetramethylethane-1,2-diamine
1,2-Bis(dimethylamino)ethane
Tetramethyldiaminoethane
Tetrameen
Propamine D
1,2-Ethanediamine, N,N,N',N'-tetramethyl-
N1,N1,N2,N2-Tetramethylethane-1,2-diamine
Tetramethyl ethylene diamine
N,N,N',N'-TETRAMETHYL-1,2-ETHANEDIAMINE
[2-(dimethylamino)ethyl]dimethylamine
MFCD00008335
tmen
1,2-Bis-(dimethylamino)ethane
Ethylenediamine, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethylethanediamine
N,N,N',N'-Tetramethyl-1,2-diaminoethane
Dimethyl(2-(dimethylamino)ethyl)amine
1,2-Di-(dimethylamino)ethane
N,N,N',N'-tetramethyl-ethane-1,2-diamine
DTXSID5026122
CHEBI:32850
K90JUB7941
Dimethyl[2-(dimethylamino)ethyl]amine
1,2-Ethanediamine, N1,N1,N2,N2-tetramethyl-
CCRIS 4870
HSDB 5396
N,N,N,N-Tetramethylethylenediamine
EINECS 203-744-6
N,N,N',N'-tetramethylethylendiamine
UN2372
UNII-K90JUB7941
AI3-26631
9U3
pentafluorophenylglycine
N,N,N',N'-tetramethyl ethylene diamine
tetramethylethlenediamine
Tetramethylethyenediamine
tetramethylethylendiamine
tetramethyl ethylenediamine
tetramethyl-ethylenediamine
tetramethylethylene diamine
tetramethylethylene-diamine
TEMED [MI]
N,N,N',N'-TETRAMETHYL-ETHYLENEDIAMINE
N,N,N',N'-tetramethylethylenediamine (TEMED)
N,N,N
SCHEMBL15334
1,2-di(dimethylamino) ethane
N,N'-tetramethylethylenediamine
1,2-bis(dimethyl-amino)ethane
DTXCID206122
CHEMBL3181913
HMS1787N22
BCP25463
n,n,n,n,-tetramethylethylenediamine
n,n,n,n-tetramethylethylene diamine
(CH3)2NCH2CH2N(CH3)2
N,N,N',N'-Tetramethylethenediamine
N,N,N',N'-Tetramethylethylenedamne
N,N,N',N'tetramethylethylenediamine
Tox21_200241
BBL011565
N,N,N',N'-tetramethylethlenediamine
N,N,N',N'-tetramethyletylenediamine
n,n,n,n -tetramethylethylene diamine
STL146736
N,N,N',N' tetramethylethylenediamine
N,N,N',N'-tetramethyl-ethylendiamin
N,N,N`,N`-Tetramethylethylenediamine
N,N,N1,N1-Tetramethylethylenediamine
AKOS000119849
n,n,n',n',-tetramethylethylenediamine
n,n,n',n'- tetramethylethylenediamine
n,n,n',n'-tetra-methylethylenediamine
N,N,N',N'-tetramethyl ethylendiamine
N,N,N',N'-tetramethyl-ethylendiamine
TEMED ULTRA-PURE GRADE 100ML
N,N, N',N'-tetramethylethylenediamine
N,N,N', N'-Tetramethylethylenediamine
N,N,N',N'-Tetramethyl ethylenediamine
N,N,N',N'-Tetramethylethylene diamine
N,N,N',N'-tetramethylethylene-diamine
UN 2372
n,n,n',n'-tetramethyl-ethylene diamine
N, N, N',N'-tetramethylethylenediamine
N,N, N', N'-tetramethylethylenediamine
N,N,N', N'-tetramethyl-ethylenediamine
N,N,N', N'-tetramethylethylene diamine
N,N,N',N'-tetra methyl ethylenediamine
NCGC00248573-01
NCGC00257795-01
BP-30082
CAS-110-18-9
N, N, N', N'-tetramethylethylenediamine
N,N,N',N'-tetra methyl ethylene diamine
N,N,N',N'-tetramethyletane-1,2-diamine
N-N-N-N-Tetramethylethylenediamine-TEMED
VS-02982
N,N,N',N' tetramethyl-1,2-ethanediamine
N,N,N2,N2-tetramethylethane-1,2-diamine
N, N, N', N'-Tetra-methylethylenediamine
N, N, N', N'-Tetramethylethylene diamine
N,N,N',N'-tetramethyl-1,2-ethylenediamine
N,N,N',N'-Tetramethylethylenediamine, 99%
T0147
T2515
1,2-Diaminoethane, N,N,N',N'-tetramethyl-
EN300-16690
5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-ylamine
D97674
N1, N1,N2,N2-tetramethylethane-1,2-diamine
TETRAMETHYLETHYLENEDIAMINE, N,N,N',N'-
A802159
N,N,N',N'-Tetramethylethylenediamine, >=99.0%
N,N,N',N'-Tetramethylethylenediamine, redistilled
J-002395
J-523208
Z56755629
F0001-0217
N,N,N',N'-TETRAMETHYL-1,2-ETHANEDIAMINE
N~1~,N~1~,N~2~,N~2~-tetramethylethane-1,2-diamine
N,N,N',N'-Tetramethylethylenediamine, Electrophoresis Grade
1,2-Di-(dimethylamino)ethane [UN2372]
N,N,N',N'-Tetramethylethylenediamine, purum, >=98.0% (GC)
N,N,N',N'-Tetramethylethylenediamine, ReagentPlus(R), 99%
InChI=1/C6H16N2/c1-7(2)5-6-8(3)4/h5-6H2,1-4H
N,N,N',N'-Tetramethylethylenediamine, >=99.5%, purified by redistillation
N,N,N',N'-Tetramethylethylenediamine, Vetec(TM) reagent grade, >=99%
N,N,N',N'-Tetramethylethylenediamine, BioReagent, for molecular biology, >=99% (GC)
N,N,N',N'-Tetramethylethylenediamine, BioReagent, suitable for electrophoresis, ~99%
N,N,N',N'-Tetramethylethylenediamine, TEMED, biochemical grade suitable for electrophoresis
TETRAMETHYLETHYLENEDIAMINE TEMED TD N,N,N
Ethylenediamine, N,N,N',N'-tetramethyl-
Dimethyl[2-(dimethylamino)ethyl]amine
N,N,N',N'-Tetramethyl-1,2-diaminoethane
N,N,N',N'-Tetramethyl-1,2-ethanediamine
N,N,N',N'-Tetramethylethanediamine
N,N,N',N'-Tetramethylethylenediamine
Tetramethyldiaminoethane
1,2-Bis(dimethylamino)ethane
(CH3)2NCH2CH2N(CH3)2
N,N,N1,N1-Tetramethylethylenediamine
Temed
1,2-Di-(dimethylamino)ethane
Propamine D
Tetrameen
Tetramethyl ethylene diamine
TMEDA
UN 2372
1,2-Diaminoethane, N,N,N',N'-tetramethyl-
N,N,N',N'-Tetramethylethenediamine
1,2-Ethanediamine, N1,N1,N2,N2-tetramethyl-
1,2-Ethanediamine,N1,N1,N2,N2-tetramethyl-
Ethylenediamine,N,N,N′,N′-tetramethyl-
1,2-Ethanediamine,N,N,N′,N′-tetramethyl
N1,N1,N2,N2-Tetramethyl-1,2-ethanediamine
N,N,N′,N′-Tetramethyl-1,2-diaminoethane
N,N,N′,N′-Tetramethyldiaminoethane
N,N,N′,N′-Tetramethylethylenediamine
1,2-Bis(dimethylamino)ethane
Dimethyl[2-(dimethylamino)ethyl]amine
TEMED
Propamine D
Tetrameen
2,5-Dimethyl-2,5-diazahexane
TMEDA
TMED
Toyocat TE
Kaolizer 11
MR
MR (amine)
N,N,N′,N′-Tetramethyl-1,2-ethanediamine
(2-(Dimethylamino)ethyl)dimethylamine
Dabco TMEDA
N,N,N′,N′-Tetramethyl-1,2-ethylenediamine
PC CAT TMEDA
Addocat 6090
Tetramethyl ethylene diamine
1258795-32-2
TMEDA
TEMED
TETRAMETHYLETHYLENEDIAMINE
N1,N1,N2,N2-tetraMethylethane-1,2-diaMine
TMED
1,4-DIAMINOBUTANE
TD
1,2-BIS(DIMETHYLAMINO)ETHANE
2,5-DiMethyl-2,5-diazahexane
N,N,N',N'-TETRAMETHYLENEDIAMINE

Tetramethylammonium chloride (Tetramethylammonium chloride) is a quaternary ammonium salt with the chemical formula (CH3)4NCl.
Tetramethylammonium chloride is a white crystalline solid that is highly soluble in water and polar organic solvents.
Tetramethylammonium chloride is known for its ability to act as a phase-transfer catalyst in organic synthesis reactions.

CAS Number: 75-57-0
EC Number: 200-880-8

Synonyms: TMAC, Tetramethylammonium chloride, N,N,N-Trimethylmethanaminium chloride, TMA chloride, TMA-Cl, Tetramethylammonium hydrochloride,Trimethylmethanaminium chloride, Tetramethylammonium chloride, N,N,N-trimethyl-methanaminium chloride



APPLICATIONS


Tetramethylammonium chloride is extensively used as a phase-transfer catalyst in organic synthesis reactions.
Tetramethylammonium chloride facilitates the transfer of ions or molecules between aqueous and organic phases, improving reaction efficiency.
Tetramethylammonium chloride is employed in the production of quaternary ammonium compounds, which are used as surfactants and detergents.

In the pharmaceutical industry, Tetramethylammonium chloride serves as a disinfectant and preservative in various formulations.
Tetramethylammonium chloride is used in the synthesis of ion-exchange resins for water purification and treatment processes.

Tetramethylammonium chloride plays a role in electroplating processes, aiding in the deposition of metals such as copper onto surfaces.
Tetramethylammonium chloride is utilized in the preparation of catalysts for organic reactions, enhancing reaction rates and selectivity.
Tetramethylammonium chloride is employed in the synthesis of corrosion inhibitors to protect metal surfaces from degradation.

Tetramethylammonium chloride serves as a stabilizer and modifier in biochemical and enzymatic reactions, facilitating protein studies.
Tetramethylammonium chloride is used in the formulation of drilling fluids in the oil and gas industry to improve viscosity and stability.

In textile manufacturing, Tetramethylammonium chloride is utilized as an antistatic agent and fabric softener in finishing processes.
Tetramethylammonium chloride finds applications in the production of specialty chemicals and additives for industrial use.
Tetramethylammonium chloride is employed in analytical chemistry as a reagent for the determination of various ions and compounds.

Tetramethylammonium chloride is used in the formulation of electrolytes for batteries and capacitors, enhancing conductivity.
Tetramethylammonium chloride plays a role in the synthesis of polymer materials, improving their solubility and processing characteristics.

In agricultural applications, Tetramethylammonium chloride is used as a plant growth regulator to enhance crop yield and quality.
Tetramethylammonium chloride finds use in the formulation of adhesives and sealants, improving bonding properties.
Tetramethylammonium chloride is employed in the manufacturing of photographic chemicals and emulsions for image development.

Tetramethylammonium chloride serves as a stabilizer and antifreeze additive in automotive and industrial cooling systems.
Tetramethylammonium chloride is utilized in the preparation of chromatography columns and stationary phases for separation techniques.

In the electronics industry, Tetramethylammonium chloride is used in the production of electronic components and materials.
Tetramethylammonium chloride finds applications in the synthesis of specialty polymers and materials for advanced technologies.
Tetramethylammonium chloride is used in the formulation of inkjet inks and printing solutions for precise and durable prints.

Tetramethylammonium chloride serves as a component in the formulation of personal care products, including hair care and skincare formulations.
Tetramethylammonium chloride continues to be explored for new applications in nanotechnology, biotechnology, and other emerging fields due to its versatile properties.

Tetramethylammonium chloride is utilized in the production of specialty chemicals and additives for industrial processes, such as metal surface treatment.
Tetramethylammonium chloride serves as a stabilizer and modifier in the formulation of paints, coatings, and adhesives, improving their performance and durability.

In the pulp and paper industry, Tetramethylammonium chloride is used as a retention aid and drainage modifier in papermaking processes.
Tetramethylammonium chloride finds applications in the formulation of construction materials, including concrete additives and waterproofing agents.

Tetramethylammonium chloride is employed in the synthesis of catalysts for polymerization reactions, enhancing the efficiency and control of polymer formation.
Tetramethylammonium chloride plays a role in the production of specialty solvents and cleaning agents for industrial and household use.

Tetramethylammonium chloride is used in the formulation of drilling muds and fluids in the mining and oil exploration industries.
In wastewater treatment, Tetramethylammonium chloride is utilized as a flocculant and coagulant to remove impurities and pollutants from water.

Tetramethylammonium chloride finds applications in the formulation of corrosion-resistant coatings and protective films for metal surfaces.
Tetramethylammonium chloride is used in the synthesis of pharmaceutical intermediates and active ingredients for therapeutic applications.

Tetramethylammonium chloride serves as a stabilizer and preservative in the formulation of cosmetic products, ensuring product stability and shelf life.
Tetramethylammonium chloride is employed in the production of herbicides and pesticides for agricultural and horticultural applications.
In the food industry, Tetramethylammonium chloride is used as a food additive and flavor enhancer, approved for certain applications.

Tetramethylammonium chloride finds use in the formulation of textile auxiliaries and dyeing agents to enhance dye uptake and color fastness.
Tetramethylammonium chloride is utilized in the manufacturing of rubber and plastic additives, improving material properties and processing characteristics.

Tetramethylammonium chloride serves as a catalyst and promoter in organic reactions, facilitating the synthesis of fine chemicals and specialty compounds.
Tetramethylammonium chloride is employed in the formulation of surfactants and emulsifiers for industrial and consumer products.

Tetramethylammonium chloride finds applications in the production of analytical reagents and standards for laboratory testing and research.
Tetramethylammonium chloride is used in the formulation of fire-retardant materials and additives for textiles and construction materials.
Tetramethylammonium chloride serves as a component in the formulation of antifouling agents and coatings for marine applications.

Tetramethylammonium chloride is utilized in the preparation of ion-selective electrodes and sensors for analytical and environmental monitoring.
Tetramethylammonium chloride finds applications in the synthesis of fluorescent dyes and markers for biological and medical imaging.

Tetramethylammonium chloride is employed in the formulation of heat transfer fluids and coolants for industrial processes and equipment.
In the textile industry, Tetramethylammonium chloride is used as a softening agent and finishing treatment to improve fabric feel and appearance.
Tetramethylammonium chloride continues to be researched for new applications in advanced materials, nanotechnology, and sustainable technologies due to its versatile chemical properties.



DESCRIPTION


Tetramethylammonium chloride (Tetramethylammonium chloride) is a quaternary ammonium salt with the chemical formula (CH3)4NCl.
Tetramethylammonium chloride is a white crystalline solid that is highly soluble in water and polar organic solvents.
Tetramethylammonium chloride is known for its ability to act as a phase-transfer catalyst in organic synthesis reactions.

Tetramethylammonium chloride consists of a tetramethylammonium cation and a chloride anion.
Tetramethylammonium chloride is commonly used in chemical processes to facilitate the transfer of ions or molecules between immiscible phases.

Tetramethylammonium chloride is employed in the synthesis of various quaternary ammonium compounds due to its versatile chemical properties.
Tetramethylammonium chloride plays a crucial role in electroplating processes, particularly in the deposition of metals like copper onto surfaces.

Tetramethylammonium chloride is utilized in the production of surfactants and detergents, contributing to their solubility and stability in aqueous solutions.
In pharmaceutical applications, Tetramethylammonium chloride is used as a disinfectant and in the formulation of certain medications.

Tetramethylammonium chloride is utilized in biochemical research as a stabilizer and facilitator in enzymatic reactions and protein studies.
Tetramethylammonium chloride is compatible with a wide range of organic solvents, making it valuable in various industrial and laboratory settings.

Tetramethylammonium chloride is employed in the preparation of ion-exchange resins for water treatment and purification processes.
Tetramethylammonium chloride is known for its low toxicity profile under normal handling and usage conditions.
Tetramethylammonium chloride is an irritant to the eyes, skin, and respiratory system and should be handled with proper precautions.

Tetramethylammonium chloride has a molecular weight of approximately 109.62 g/mol and a melting point around 232-234°C.
Tetramethylammonium chloride exhibits high thermal stability, maintaining its properties under moderate temperature conditions.

Tetramethylammonium chloride is stable under recommended storage conditions, away from moisture and direct sunlight.
Tetramethylammonium chloride is synthesized through the reaction of trimethylamine with hydrochloric acid or chloride salts.

Tetramethylammonium chloride is used in the synthesis of corrosion inhibitors and additives for industrial applications.
Tetramethylammonium chloride enhances the solubility and stability of certain compounds in aqueous solutions, facilitating their use in various industries.

Tetramethylammonium chloride's chemical structure provides it with cationic properties that interact effectively with anionic species in solution.
Tetramethylammonium chloride is employed in the preparation of catalysts for organic transformations, facilitating efficient and selective reactions.

Tetramethylammonium chloride is a versatile chemical reagent that finds applications in analytical chemistry and quality control processes.
Tetramethylammonium chloride is classified as a hazardous material and should be handled and disposed of according to safety guidelines and regulations.
Researchers continue to explore new applications and formulations of Tetramethylammonium chloride to meet evolving industrial and scientific demands.



PROPERTIES


Physical Properties:

Molecular Formula: (CH3)4NCl
Molecular Weight: Approximately 109.62 g/mol
Appearance: White crystalline solid
Odor: Odorless
Density: 1.01 g/cm³ at 25°C
Melting Point: 232-234°C (449-453°F)
Boiling Point: Decomposes before boiling
Solubility in Water: Soluble
Solubility in Other Solvents: Soluble in polar organic solvents
pH: Neutral (around 7 in aqueous solution)
Vapor Pressure: Negligible


Chemical Properties:

Chemical Structure: Tetramethylammonium cation (
Hygroscopicity: Hygroscopic (absorbs moisture from the air)
Stability: Stable under normal conditions
Reactivity:
Tetramethylammonium chloride is a quaternary ammonium salt and acts as a phase-transfer catalyst.
It is not reactive with most acids and bases under standard conditions.
Tetramethylammonium chloride decomposes at high temperatures, releasing toxic fumes.
Flammability: Non-flammable
Corrosivity: Non-corrosive to metals under normal conditions
Autoignition Temperature: Not applicable (decomposes before ignition)



FIRST AID


Inhalation:

Symptoms:
Inhalation of Tetramethylammonium chloride vapors may cause respiratory irritation, coughing, difficulty breathing, and throat irritation.

Immediate Actions:
Remove the affected person from the exposure area to fresh air immediately, ensuring they can breathe freely.
If breathing is difficult, provide oxygen if available.
Assist ventilation if necessary.
Keep the person calm and in a comfortable position.

Medical Attention:
Seek immediate medical attention.
Provide the medical personnel with the Safety Data Sheet (SDS) or chemical name for proper treatment guidance.
Monitor the person for signs of respiratory distress.


Skin Contact:

Symptoms:
Tetramethylammonium chloride can cause skin irritation, redness, and potentially burns upon prolonged contact.

Immediate Actions:
Remove contaminated clothing and jewelry immediately.
Wash the affected area thoroughly with soap and water for at least 15 minutes, ensuring all chemical residue is removed.
If irritation persists or there are signs of burns, seek medical attention promptly.

Medical Attention:
Consult a physician if skin irritation or burns occur.
Provide the SDS or chemical name to medical personnel for appropriate treatment.


Eye Contact:

Symptoms:
Eye exposure to Tetramethylammonium chloride can cause irritation, redness, pain, and potential corneal injury.

Immediate Actions:
Immediately rinse eyes with gently flowing water for at least 15 minutes, holding eyelids open to ensure thorough flushing.
Remove contact lenses, if present and easily removable, during rinsing.
Seek medical attention immediately after rinsing.

Medical Attention:
Contact an eye specialist or ophthalmologist promptly.
Provide the SDS or chemical name to medical personnel for proper evaluation and treatment.


Ingestion:

Symptoms:
Ingestion of Tetramethylammonium chloride may cause gastrointestinal irritation, nausea, vomiting, and abdominal pain.

Immediate Actions:
Do not induce vomiting unless instructed by medical personnel.
Rinse out the mouth with water if the person is conscious and able to swallow.
Seek immediate medical attention.

Medical Attention:
Contact a poison control center or healthcare provider immediately.
Provide the SDS or chemical name to medical personnel for appropriate treatment guidance.



HANDLING AND STORAGE


Handling:

General Precautions:
Handle Tetramethylammonium chloride in a well-ventilated area to minimize exposure to vapors.
Use appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and lab coat.
Avoid inhalation of vapors and contact with skin and eyes.
Do not eat, drink, or smoke while handling Tetramethylammonium chloride.

Handling Practices:
Use tools and equipment that are grounded and spark-resistant to prevent static electricity discharge.
Ensure containers are tightly closed when not in use to prevent spills and evaporation.
Minimize exposure to heat, flames, and ignition sources during handling and transfer operations.
Handle with care to prevent physical damage to containers and potential release of the chemical.

Emergency Procedures:
Be familiar with emergency procedures and spill response measures before handling Tetramethylammonium chloride.
Have spill control materials (e.g., absorbent pads, neutralizing agents) readily available.
In case of spillage, contain the spill immediately to prevent further spread. Wear appropriate PPE during cleanup.

Hygiene Practices:
Wash hands and any exposed skin thoroughly with soap and water after handling Tetramethylammonium chloride.
Remove contaminated clothing and wash it before reuse.
Maintain good housekeeping practices in work areas to minimize potential exposure.

Specific Handling Guidance:
Do not mix Tetramethylammonium chloride with incompatible substances, such as strong oxidizers and acids.
Follow manufacturer's recommendations and safety data sheet (SDS) instructions for handling and disposal.
Ensure that all handling procedures comply with local, state, and federal regulations.


Storage:

Storage Location:
Store Tetramethylammonium chloride in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed and upright to prevent leakage and evaporation.
Store away from incompatible materials, including strong acids, bases, and oxidizing agents.

Temperature Control:
Maintain storage temperature below 30°C (86°F) to prevent decomposition and ensure chemical stability.
Avoid freezing temperatures, as Tetramethylammonium chloride may crystallize and affect product quality.

Container Requirements:
Use original containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Ensure containers are labeled with the chemical name, hazards, and handling instructions.
Inspect containers regularly for signs of damage or deterioration.

Segregation:
Store Tetramethylammonium chloride separately from food, feedstuffs, and animal bedding to prevent contamination.
Segregate from oxidizing agents and strong reducing agents to avoid potential reactions.

Security and Accessibility:
Restrict access to storage areas to authorized personnel only.
Ensure emergency equipment, such as spill kits and fire extinguishers suitable for chemical fires, is readily accessible.

Inventory Management:
Implement a first-in, first-out (FIFO) inventory system to ensure older stock is used first.
Keep accurate records of quantities stored, usage, and disposal to facilitate inventory control and regulatory compliance.

Tetramethylbis(aminoethyl)ether, also known as N,N,N',N'-Tetramethylbis(2-aminoethyl)ether or N,N,N',N'-Tetramethylbis(2-aminoethyl) ether, is a chemical compound with the molecular formula C8H20N2O.
Tetramethylbis(aminoethyl)ether is a diamine ether compound with four methyl groups and two aminoethyl groups attached to the oxygen atom.
Tetramethylbis(aminoethyl)ether colorless and transparent liquid or Brown liquid.

CAS Number: 3033-62-3
Molecular Formula: C8H20N2O
Molecular Weight: 160.26
EINECS Number: 221-220-5

3033-62-3, BIS(2-DIMETHYLAMINOETHYL) ETHER, Bis(2-dimethylaminoethyl)ether, 2,2'-oxybis(N,N-dimethylethanamine), Niax catalyst al, Kalpur PC, Niax A 1, Toyocat ET, Toyocat ETS, Dabco BL 11, Texacat ZF 20, Dabco BL 19I, Dabco BL 19, Niax A 4, Niax A 99, A 99 (Amine), Ethanamine, 2,2'-oxybis[N,N-dimethyl-, 2-Dimethylaminoethyl Ether, Bis(2-(dimethylamino)ethyl)ether, Bis(2-(dimethylamino)ethyl) ether, N,N,N',N'-Tetramethyl-2,2'-oxybis(ethylamine), NSC 109887, 2,2'-Oxybis(N,N-dimethylethylamine), Bis[2-(N,N-dimethylamino)ethyl] ether, Ethanamine, 2,2'-oxybis(N,N-dimethyl-, 2-[2-(dimethylamino)ethoxy]-N,N-dimethylethanamine, dimethylaminoethyl ether, Bis[2-(dimethylamino)ethyl]ether, A 99, Ethylamine, 2,2'-oxybis(N,N-dimethyl-, Ethylamine, 2,2'-oxybis[N,N-dimethyl-, NL66Q36V7L, DTXSID5027512, {2-[2-(dimethylamino)ethoxy]ethyl}dimethylamine, Bis[2-(dimethylamino)ethyl] ether, NSC-109887, DTXCID807512, 2,2'-Oxybis[N,N-dimethylethylamine], CAS-3033-62-3, 2-(2-(dimethylamino)ethoxy)-N,N-dimethylethanamine, EINECS 221-220-5, BRN 1739668, UNII-NL66Q36V7L, 2-(Dimethylamino)ethyl ether, HSDB 7903, bis (2-dimethylaminoethyl) ether, 1,5-Bis(dimethylamino)-3-oxapentane, 2,N-dimethylethylamine], EC 221-220-5, SCHEMBL15091, 4-04-00-01441 (Beilstein Handbook Reference), 59948-21-9, N,N,N',N'-Tetramethyl-3-oxapentane-1,5-diamine, 2-[2-(dimethylamino)ethoxy]-N,N-dimethyl-ethanamine, bis(N,N-dimethylaminoethyl)ether, CHEMBL1899933, Bis(2-dimethylaminoethyl) ether, bis-(2-dimethylaminoethyl) ether, WLN: 1N1&2 2O, Tox21_202013, Tox21_303216, Ethanamine,2'-oxybis[N,N-dimethyl-, Ethylamine,2'-oxybis[N,N-dimethyl-, MFCD00059199, NSC109887, bis[2-(n,n-dimethylamino)ethyl]ether, AKOS006220473, di-[2-(n,n-dimethylaminoethyl)]ether, NCGC00164210-01, NCGC00164210-02, NCGC00257033-01, NCGC00259562-01, Bis-[2-(N,N-dimethylamino)ethyl] ether, BS-22895, B1291, CS-0077112, FT-0623004, NS00005315, Bis[2-(N,N-dimethylamino)ethyl] ether, 97%, EN300-205166, BIS (2-DIMETHYLAMINOETHYL) ETHER [HSDB], N,N,N',N'-TETRAMETHYLBISAMINOETHYL ETHER, A820326, J-017914, J-519864, Q20965408, F0001-0931, Z276157630, N-(2-[2-(Dimethylamino)ethoxy]ethyl)-N,N-dimethylamine #, 2,2'-Oxybis(N,N-dimethylethanamine) (Bis[2-(dimethylamino)ethyl] Ether; N,N

Tetramethylbis(aminoethyl)ether soluble in water, easily soluble in alcohol, benzene, etc.
Tetramethylbis(aminoethyl)ether appears as a clear or yellow liquid. Bp: 188°C.
Toxic by inhalation, by skin absorption, ingestion, and eye contact.

Tetramethylbis(aminoethyl)ether is a tridentate ligand.
Tetramethylbis(aminoethyl)ether assists in the formation and stabilization of intermediates during the exchange reactions.
Tetramethylbis(aminoethyl)ether can act as a catalyst or a chain extender in polymerization reactions, particularly in the production of polyurethanes and epoxy resins.

Tetramethylbis(aminoethyl)ether is used as an ion-pairing agent in analytical chemistry techniques, such as liquid chromatography-mass spectrometry (LC-MS), to enhance the separation and detection of certain analytes.
In some formulations, Tetramethylbis(aminoethyl)ether serves as a crosslinking agent, contributing to the formation of three-dimensional networks in polymers and coatings, improving their mechanical properties and chemical resistance.
Tetramethylbis(aminoethyl)ether can be used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals.

Tetramethylbis(aminoethyl)ether may act as a catalyst or co-catalyst in certain organic reactions, such as Michael addition reactions, Mannich reactions, and reductive amination reactions.
Tetramethylbis(aminoethyl)ether is added as an additive to modify solvent properties, such as polarity and viscosity, to suit specific applications in chemical processes.
Tetramethylbis(aminoethyl)ether can be used as an additive to improve combustion efficiency, reduce emissions, and enhance fuel stability.

Tetramethylbis(aminoethyl)ether is also utilized in research laboratories for various experimental purposes, including chemical synthesis, catalysis studies, and material science research.
Tetramethylbis(aminoethyl)ether is employed as a crosslinking agent in the formulation of adhesives and sealants.
Tetramethylbis(aminoethyl)ether helps to create strong bonds between polymer chains, improving the adhesion and cohesion of the final product.

In the textile industry, Tetramethylbis(aminoethyl)ether is used as a finishing agent for fabrics.
Tetramethylbis(aminoethyl)ether can impart desirable properties to textiles, such as wrinkle resistance, flame retardancy, and color fastness.
Tetramethylbis(aminoethyl)ether finds application in leather processing as a tanning agent or a crosslinking agent in leather finishes.

Tetramethylbis(aminoethyl)ether helps to improve the durability, flexibility, and water resistance of leather products.
Tetramethylbis(aminoethyl)ether can be used as an additive in diesel exhaust fluids (DEF) to reduce nitrogen oxide (NOx) emissions in diesel engines.
Tetramethylbis(aminoethyl)ether reacts with NOx to convert it into harmless nitrogen and water vapor.

In the paper manufacturing process, Tetramethylbis(aminoethyl)ether is utilized as a wet-strength resin additive.
Tetramethylbis(aminoethyl)ether improves the strength and durability of paper products, especially in wet conditions, such as tissue paper and paper towels.
Tetramethylbis(aminoethyl)ether may be included in cosmetics and personal care products as a pH adjuster or buffering agent to maintain the desired pH level of formulations, ensuring product stability and skin compatibility.

Tetramethylbis(aminoethyl)ether is used as a scavenger for hydrogen sulfide (H2S) in various industrial processes, such as natural gas purification, petroleum refining, and wastewater treatment, helping to reduce odor and corrosion issues.
Tetramethylbis(aminoethyl)ether can be employed in water treatment applications as a chelating agent to remove heavy metal ions from water, improving water quality and reducing environmental pollution.
Tetramethylbis(aminoethyl)ether is sometimes added to plastics, coatings, and textiles as an antistatic agent to prevent static electricity buildup and reduce surface conductivity.

Tetramethylbis(aminoethyl)ether serves as a reagent in chemical laboratories for various analytical and synthetic purposes, including organic synthesis, coordination chemistry, and molecular biology applications.
In the paper recycling industry, Tetramethylbis(aminoethyl)ether can be used as a deinking agent to remove ink from recycled paper pulp, facilitating the production of high-quality recycled paper products.
Tetramethylbis(aminoethyl)ether is utilized as a fire retardant additive in certain materials, such as textiles, plastics, and coatings, to improve their fire resistance and meet safety standards.

Tetramethylbis(aminoethyl)ether can be added to antifreeze formulations to lower the freezing point of water-based solutions, preventing the formation of ice and protecting engines and cooling systems from cold temperatures.
Due to its hygroscopic properties, Tetramethylbis(aminoethyl)ether can be used as a humidity indicator in certain products or packaging materials, changing color or appearance in response to changes in relative humidity.

Tetramethylbis(aminoethyl)ether can act as a preservative in certain formulations, helping to extend the shelf life of products by inhibiting the growth of bacteria, fungi, and other microorganisms.
Tetramethylbis(aminoethyl)ether can be employed as a deicing agent on roads, sidewalks, and airport runways to melt ice and snow, improving traction and safety during winter weather conditions.

Boiling point: 189 °C/760 mmHg
Density: 0.841 g/mL at 25 °C
vapor pressure: 49Pa at 20℃
refractive index: n 20/D 1.430
Flash point: 151 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in water
form: clear liquid
pka: 9.12±0.28(Predicted)
color: Colorless to Light yellow
Viscosity: 1.53mm2/s
Water Solubility: 100g/L at 20℃
BRN: 1739668
Exposure limits ACGIH: TWA 0.05 ppm; STEL 0.15 ppm (Skin)
InChIKey: GTEXIOINCJRBIO-UHFFFAOYSA-N
LogP: -0.34 at 20℃

Reaction of V and SO3 or chlorosulfonic acid.
Reaction of Tetramethylbis(aminoethyl)ether with dichloroethyl ether or dimethylaminoethoxyethyl ether.
One-step synthesis of Tetramethylbis(aminoethyl)ether under solid catalyst.

In certain formulations, Tetramethylbis(aminoethyl)ether can act as a surfactant or wetting agent, facilitating the dispersion of particles and improving the wetting properties of surfaces.
Due to its hygroscopic nature, Tetramethylbis(aminoethyl)ether is used in some applications where moisture absorption or control is necessary, such as in certain industrial processes or hygroscopic formulations.
Tetramethylbis(aminoethyl)ether exhibits antimicrobial properties and can be incorporated into products like disinfectants, sanitizers, and antimicrobial coatings to inhibit the growth of microorganisms and prevent contamination.

Tetramethylbis(aminoethyl)ether is employed in gas treatment processes, such as gas purification or scrubbing, to remove impurities like hydrogen sulfide (H2S), carbon dioxide (CO2), or sulfur dioxide (SO2) from gas streams.
In metalworking fluids, Tetramethylbis(aminoethyl)ether can serve as a corrosion inhibitor or lubricity enhancer, improving the performance and longevity of metalworking processes like cutting, grinding, or machining.
Tetramethylbis(aminoethyl)ether is sometimes added to coolant formulations to improve heat transfer properties and prevent corrosion in cooling systems, such as automotive radiators or industrial heat exchangers.

Tetramethylbis(aminoethyl)ether can be used as a humectant in certain formulations, particularly in skincare or haircare products, to help retain moisture and prevent drying of the skin or hair.
In the mining industry, Tetramethylbis(aminoethyl)ether may be employed as a flotation agent in ore processing to selectively separate valuable minerals from gangue materials based on their hydrophobicity.
Tetramethylbis(aminoethyl)ether is utilized as a softening agent in textile finishing processes to impart a soft and smooth hand feel to fabrics.

Tetramethylbis(aminoethyl)ether can be added to electrolyte solutions, such as those used in batteries or electrochemical processes, to improve conductivity and electrolyte performance.
In gasoline formulations, Tetramethylbis(aminoethyl)ether may be used as an additive to enhance fuel stability, improve combustion efficiency, and reduce engine emissions.
Tetramethylbis(aminoethyl)ether can serve as an admixture in concrete formulations to improve workability, reduce water requirements, and enhance the strength and durability of concrete structures.

Tetramethylbis(aminoethyl)ether reacts as a base.
Reacts exothermically with acids.
May form explosive peroxides upon exposure to the air.

The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination.
Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier.
Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with environmental and public health regulations.

In the photographic industry, Tetramethylbis(aminoethyl)ether may be used as a developing agent or additive in photographic processing solutions to enhance image development and quality.
Tetramethylbis(aminoethyl)ether can be added to hydraulic fluids to improve their lubricating properties, reduce friction and wear in hydraulic systems, and enhance overall performance and efficiency.
Tetramethylbis(aminoethyl)ether is utilized as a flame retardant additive in certain materials, such as plastics, textiles, and foams, to reduce the risk of ignition and slow down the spread of flames in fire situations.

In some food applications, Tetramethylbis(aminoethyl)ether may be used as a pH regulator, buffering agent, or processing aid, ensuring proper pH levels and enhancing product stability.
Tetramethylbis(aminoethyl)ether can be incorporated into agricultural formulations, such as pesticides or fertilizers, to improve their dispersibility, compatibility, and effectiveness in crop protection or nutrient delivery.
Tetramethylbis(aminoethyl)ether can be included in air freshener formulations to neutralize odors and impart pleasant fragrances to indoor environments.

Tetramethylbis(aminoethyl)ether serves as a metal chelator or sequestering agent in certain industrial processes to prevent the precipitation of metal ions, reduce scale formation, and minimize corrosion.
In the rubber industry, Tetramethylbis(aminoethyl)ether may be added to rubber compounds as a processing aid, plasticizer, or vulcanization accelerator to improve rubber properties and processing characteristics.

Uses:
Tetramethylbis(aminoethyl)ether is an efficient tertiary amine catalyst, which is suitable for the production of almost all foam products, mainly for the production of flexible foam products, especially for high resilience and RIM products.
Tetramethylbis(aminoethyl)ether is characterized by high catalytic activity, smooth foaming, large tolerance to tin, easy to adjust the formulation, and the physical and chemical properties of products produced with it, such as resilience and elongation, are better than other products.
Tetramethylbis(aminoethyl)ether exhibits antimicrobial properties and can be incorporated into products like disinfectants, sanitizers, and antimicrobial coatings to inhibit the growth of microorganisms and prevent contamination.

Tetramethylbis(aminoethyl)ether is employed in gas treatment processes, such as gas purification or scrubbing, to remove impurities like hydrogen sulfide (H2S), carbon dioxide (CO2), or sulfur dioxide (SO2) from gas streams.
In metalworking fluids, Tetramethylbis(aminoethyl)ether can serve as a corrosion inhibitor or lubricity enhancer, improving the performance and longevity of metalworking processes like cutting, grinding, or machining.
Tetramethylbis(aminoethyl)ether is sometimes added to coolant formulations to improve heat transfer properties and prevent corrosion in cooling systems, such as automotive radiators or industrial heat exchangers.

Tetramethylbis(aminoethyl)ether can be used as a humectant in certain formulations, particularly in skincare or haircare products, to help retain moisture and prevent drying of the skin or hair.
In the mining industry, Tetramethylbis(aminoethyl)ether may be employed as a flotation agent in ore processing to selectively separate valuable minerals from gangue materials based on their hydrophobicity.
Tetramethylbis(aminoethyl)ether is utilized as a softening agent in textile finishing processes to impart a soft and smooth hand feel to fabrics.

Tetramethylbis(aminoethyl)ether can be added to electrolyte solutions, such as those used in batteries or electrochemical processes, to improve conductivity and electrolyte performance.
In gasoline formulations, Tetramethylbis(aminoethyl)ether may be used as an additive to enhance fuel stability, improve combustion efficiency, and reduce engine emissions.
Tetramethylbis(aminoethyl)ether can serve as an admixture in concrete formulations to improve workability, reduce water requirements, and enhance the strength and durability of concrete structures.

Tetramethylbis(aminoethyl)ether is used in the manufacturing of flexible polyurethane foams.
As a high-efficiency tertiary amine catalyst, Tetramethylbis(aminoethyl)ether is suitable for the production of almost all foam plastic products, mainly for the production of flexible foam products, especially suitable for high resilience and RIM products.
Tetramethylbis(aminoethyl)ether is characterized by large catalytic activity, smooth foaming, large tolerance to tin, easy to adjust the formula, and the physical and chemical properties of products produced with it, such as rebound rate and elongation, are superior to other products.

Tetramethylbis(aminoethyl)ether is utilized as a catalyst or co-catalyst in various organic reactions, such as Michael addition reactions, Mannich reactions, and reductive amination reactions.
Tetramethylbis(aminoethyl)ether can act as a catalyst or chain extender in polymerization reactions, particularly in the production of polyurethanes and epoxy resins.
Tetramethylbis(aminoethyl)ether is used as an ion-pairing agent in analytical chemistry techniques, such as liquid chromatography-mass spectrometry (LC-MS), to enhance the separation and detection of certain analytes.

In certain formulations, Tetramethylbis(aminoethyl)ether serves as a crosslinking agent, contributing to the formation of three-dimensional networks in polymers and coatings, improving their mechanical properties and chemical resistance.
Tetramethylbis(aminoethyl)ether is used as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and specialty chemicals.
Tetramethylbis(aminoethyl)ether is employed in gas treatment processes, such as gas purification or scrubbing, to remove impurities like hydrogen sulfide (H2S), carbon dioxide (CO2), or sulfur dioxide (SO2) from gas streams.

Tetramethylbis(aminoethyl)ether is used as a crosslinking agent in the formulation of adhesives and sealants, improving the adhesion and cohesion of the final product.
Tetramethylbis(aminoethyl)ether is used as a finishing agent for fabrics in the textile industry, imparting desirable properties such as wrinkle resistance, flame retardancy, and color fastness.
Tetramethylbis(aminoethyl)ether finds application in leather processing as a tanning agent or a crosslinking agent in leather finishes, improving the durability and water resistance of leather products.

Tetramethylbis(aminoethyl)ether can be employed in water treatment applications as a chelating agent to remove heavy metal ions from water, improving water quality and reducing environmental pollution.
Tetramethylbis(aminoethyl)ether is added to plastics, coatings, and textiles as an antistatic agent to prevent static electricity buildup and reduce surface conductivity.
Tetramethylbis(aminoethyl)ether serves as a reagent in chemical laboratories for various analytical and synthetic purposes, including organic synthesis, coordination chemistry, and molecular biology applications.

In the paper recycling industry, Tetramethylbis(aminoethyl)ether can be used as a deinking agent to remove ink from recycled paper pulp, facilitating the production of high-quality recycled paper products.
Tetramethylbis(aminoethyl)ether is utilized as a fire retardant additive in materials such as textiles, plastics, and coatings to improve their fire resistance and meet safety standards.
Tetramethylbis(aminoethyl)ether acts as a surfactant or wetting agent, facilitating the dispersion of particles and improving the wetting properties of surfaces.

Due to its hygroscopic nature, Tetramethylbis(aminoethyl)ether is used in applications where moisture absorption or control is necessary, such as in certain industrial processes or hygroscopic formulations.
Tetramethylbis(aminoethyl)ether acts as a preservative in certain formulations, helping to extend the shelf life of products by inhibiting the growth of bacteria, fungi, and other microorganisms.
Tetramethylbis(aminoethyl)ether can be employed as a deicing agent on roads, sidewalks, and airport runways to melt ice and snow, improving traction and safety during winter weather conditions.

In the photographic industry, Tetramethylbis(aminoethyl)ether may be used as a developing agent or additive in photographic processing solutions to enhance image development and quality.
Tetramethylbis(aminoethyl)ether can be used as a humidity indicator in certain products or packaging materials, changing color or appearance in response to changes in relative humidity.

Safety Profile:
Poison by skin contact.
Moderately toxic by ingestion.
Experimental reproductiveeffects.

A severe skin and eye irritant.
Tetramethylbis(aminoethyl)ether can cause irritation to the skin, eyes, and respiratory tract upon contact or inhalation.
Prolonged or repeated exposure may lead to dermatitis, redness, itching, or respiratory irritation.

Tetramethylbis(aminoethyl)ether has the potential to sensitize individuals upon repeated exposure, leading to allergic reactions such as allergic dermatitis or respiratory sensitization.
Ingestion or inhalation of Tetramethylbis(aminoethyl)ether in large quantities may cause systemic toxicity, affecting various organs and systems in the body.
Symptoms of toxicity may include nausea, vomiting, headache, dizziness, or central nervous system depression.

Tetramethylbis(aminoethyl)ether may pose environmental hazards if released into the environment.
Tetramethylbis(aminoethyl)ether can be harmful to aquatic organisms and may persist in the environment, leading to long-term ecological impacts.
Tetramethylbis(aminoethyl)ether itself is not highly flammable, it may contribute to the flammability of surrounding materials if involved in a fire.

Tetramethylbis(aminoethyl)ether should be stored away from sources of ignition and combustible materials.
Tetramethylbis(aminoethyl)ether may react with certain chemicals or materials under specific conditions, leading to the generation of hazardous by-products or increased fire or explosion risks.

Storage and Handling:
Proper storage and handling of Tetramethylbis(aminoethyl)ether are essential to minimize risks.
Tetramethylbis(aminoethyl)ether should be stored in a cool, well-ventilated area away from incompatible materials, sources of heat, and direct sunlight.
Personal protective equipment (PPE), including gloves, goggles, and respiratory protection, should be worn when handling this substance.

Tetramethyldipropylenetriamine is a colorless to yellowish transparent liquid with fishy odor.
Tetramethyldipropylenetriamine is a non-emitting amine balanced catalyst, which is slightly selective for urea (isocyanate-water) reaction.


CAS Number: 6711-48-4
EC Number: 229-761-9
MDL Number: MFCD00014880
Linear Formula: HN[(CH2)3N(CH3)2]2
Molecular Formula: C10H25N3



SYNONYMS:
FENTACAT 15, PC15, tetramethyldipropylenetriamine, Bis-(dimethylaminopropyl)amine, Tetramethyl dippropylene triamine, Tetramethyl-1,3-Propylenetriamine, Bis(3-dimethylamino-1-propyl)amine, N,N-BIS-(3-DIMETHYLAMINOPROPYL)AMINE, 3,3'-BIS(DIMETHYLAMINO)-DIPROPYLAMINE, 2,6,10-Triazaundecane, 2,10-dimethyl-, 3,3'-iminobis(N,N-dimethylpropylamine), 3,3'-IMINOBIS(N,N-DIMETHYLPROPYLAMINE), Dipropylamine, 3,3'-bis(dimethylamino)-, N,N,N',N'—tetramethyldipropylenetriamine, N,N,N',N'-tetramethyldipropylenetriamine, 3,3'-imino pairs (N,N-dimethyl propylamine), Dipropylenetriamine, N,N,N',N'-tetramethyl-, N′-[3-(Dimethylamino)propyl]-N,N-dimethylpropan-1,3-diamin, 1,3-Propanediamine, N-3-(dimethylamino)propyl-N,N-dimethyl-, 3-Propanediamine,N'-[3-(dimethylamino)propyl]-N,N-dimethyl-1, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, PC15, 3,3'-BIS(DIMETHYLAMINO)-DIPROPYLAMINE, 3,3'-IMINOBIS(N,N-DIMETHYLPROPYLAMINE), BIS(3-DIMETHYLAMINOPROPYL)AMINE, LUPRAGEN(R) N 109, N,N-BIS-(3-DIMETHYLAMINOPROPYL)AMINE, 2,6,10-Triazaundecane, 2,10-dimethyl-, 3-Propanediamine,N’-[3-(dimethylamino)propyl]-N,N-dimethyl-1, Bis(3-dimethylamino-1-propyl)amine, Bis-(dimethylaminopropyl)amine, Dipropylamine, 3,3'-bis(dimethylamino)-, Dipropylenetriamine, N,N,N',N'-tetramethyl-, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, N,N,N',N'-Tetramethyldipropylenetriamine, n,n,n’,n’-tetramethyl-dipropylenetriamin, n,n,n’,n’-tetramethyldipropylenetriamine, N’-[3-(Dimethylamino)propyl]-N,N-dimethyl-1,3-propanediamine, n’-[3-(dimethylamino)propyl]-n,n-dimethyl-3-propanediamine, N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, N,N,N',N'-Tetramethyliminobis(propylamine), 1,3-Propanediamine, N-3-(dimethylamino)propyl-N,N-dimethyl-, tetramethyliminobis-(propylamine), bis-(dimethylaminopropyl)amine, fentamine tmbpa, lupragen(r) n 109, bis(3-dimethylaminopropyl)amin, polycat-15, tetramethyldipropylenetriamine, 3,3&prime, jeffcat z 130, bis(3-dimethylaminopropyl)amine, FENTACAT 15, N,N,N',N'—tetramethyldipropylenetriamine, N,N-Bis[3-(dimethylamino)propylamine, 3,3'-IMINOBIS(N,N-DIMETHYLPROPYLAMINE), N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, (3-{[3-(dimethylamino)propyl]amino}propyl)dimethylamine, DTXSID7044974, 3,3'-Iminobis(N,N-dimethylpropylamine), 97%, (3-{[3-(dimethylamino)propyl]amino}propyl)dimethylamine, Bis-(dimethylaminopropyl)amine, CS-W016846, W-104730, AKOS000120187, 3,3'-Iminobis(N,N-dimethyl-propylamine), CW8R6R660G, NCGC00256130-01, 3,3&priMe,Polycat-15,FENTACAT 15,Jeffcat Z 130,FENTAMINE TMBPA,LUPRAGEN(R) N 109,Niax* Catalyst C-15,tetramethyldipropylenetriamine,Bis(3-dimethylaminopropyl)amin,-Dihexyloxacarbocyanine Iodide, Bis(3-dimethylamino-1-propyl)amine, Bis-(dimethylaminopropyl)amine, Bis(3-(dimethylamino)propyl)amine, Dipropylamine, 3,3'-bis(dimethylamino)-, Dipropylenetriamine, N,N,N',N'-tetramethyl-, N,N,N',N'-Tetramethyldipropylenetriamine, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, 2,6,10-Triazaundecane, 2,10-dimethyl-, 3,3'-Iminobis(N,N-dimethylpropylamine), N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, DTXSID7044974, 3,3'-Iminobis(N,N-dimethylpropylamine), 97%, (3-{[3-(dimethylamino)propyl]amino}propyl)dimethylamine, Bis-(dimethylaminopropyl)amine, CS-W016846, W-104730, AKOS000120187, 3,3'-Iminobis(N,N-dimethyl-propylamine), CW8R6R660G, NCGC00256130-01, N,N,N',N'-tetramethyldipropylenetriamine, N,N-BIS-(3-DIMETHYLAMINOPROPYL)AMINE, 2,6,10-Triazaundecane, 2,10-dimethyl-, 3-Propanediamine,N'-[3-(dimethylamino)propyl]-N,N-dimethyl-1, Bis(3-dimethylamino-1-propyl)amine, Bis-(dimethylaminopropyl)amine, Dipropylamine, 3,3'-bis(dimethylamino)-, Dipropylenetriamine, N,N,N',N'-tetramethyl-, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, Tetramethyl dippropylene triamine, N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, 3,3'-imino pairs (N,N-dimethyl propylamine), Tetramethyl-1,3-Propylenetriamine, tetramethyliminobispropylamine, Tetramethyl dipropylenetriamine, 1,1,9,9-Tetramethyl-1,5,9-triazanonane, 2,10-Dimethyl-2,6,10-triazaundecane, 3′-Iminobis(N,N-dimethylpropylamine), Bis[3-(dimethylamino)propyl]amine, N,N,N′,N′-Tetramethyldipropylenetriamine, N,N,N′,N′-Tetramethyliminobispropylamine, N-(3-Dimethylaminopropyl)-N′,N′-dimethylpropane-1,3-diamine, (3-[[3-(Dimethylamino)propyl]amino]propyl)dimethylamine, N3-[3-(Dimethylamino)propyl]-N1,N1-dimethyl-1,3-propanediamine, 3,3′-Iminobis(N,N-dimethylpropylamine), 3,3'-Iminobis(N,N-dimethylpropylamine), N1-(3-(Dimethylamino)propyl)-N3,N3-dimethylpropane-1,3-diamine, 1,3-Propanediamine,N3-[3-(dimethylamino)propyl]-N1,N1-dimethyl-, 3,3'-Iminobis(N,N-dimethylpropylamine), Bis-(dimethylaminopropyl)amine, N-[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine, 1,3-Propanediamine,N3-[3-(dimethylamino)propyl]-N1,N1-dimethyl-, Dipropylamine,3,3′-bis(dimethylamino)-, 1,3-Propanediamine,N′-[3-(dimethylamino)propyl]-N,N-dimethyl-, N3-[3-(Dimethylamino)propyl]-N1,N1-dimethyl-1,3-propanediamine, 2,6,10-Triazaundecane,2,10-dimethyl-, Bis[3-(dimethylamino)propyl]amine, 3,3′-Iminobis(N,N-dimethylpropylamine), 2,10-Dimethyl-2,6,10-triazaundecane, N′-[3-(Dimethylamino)propyl]-N,N-dimethyl-1,3-propanediamine, Tetramethyldipropylenetriamine, Polycat 70/15, Polycat 15, 1,1,9,9-Tetramethyl-1,5,9-triazanonane, N,N,N′,N′-Tetramethyliminobispropylamine, N,N-Bis[3-(dimethylamino)propyl]amine, 3′-Iminobis(N,N-dimethylpropylamine), NSC 129937, Jeffcat Z 130, Z 130, Polycat 9, N-(3-Dimethylaminopropyl)-N′,N′-dimethylpropane-1,3-diamine, Zeffcat Z 130, N,N,N′′,N′′-Tetramethyldipropylenetriamine, CT 18L, ZR 50B, PC 9, N,N,N′,N′-Tetramethyldipropylenetriamine, PC 15, (3-[[3-(Dimethylamino)propyl]amino]propyl)dimethylamine, 86003-72-7, 136363-31-0, 1467059-84-2, 1,3-Propanediamine, N3-[3-(dimethylamino)propyl]-N1,N1-dimethyl-, Dipropylamine, 3,3′-bis(dimethylamino)-, 1,3-Propanediamine, N′-[3-(dimethylamino)propyl]-N,N-dimethyl-, N3-[3-(Dimethylamino)propyl]-N1,N1-dimethyl-1,3-propanediamine, 2,6,10-Triazaundecane, 2,10-dimethyl-, Bis[3-(dimethylamino)propyl]amine, 3,3′-Iminobis(N,N-dimethylpropylamine), 2,10-Dimethyl-2,6,10-triazaundecane, N′-[3-(Dimethylamino)propyl]-N,N-dimethyl-1,3-propanediamine, Tetramethyldipropylenetriamine, Polycat 70/15, Polycat 15, 1,1,9,9-Tetramethyl-1,5,9-triazanonane, N,N,N′,N′ Tetramethyliminobispropylamine, N,N-Bis[3-(dimethylamino)propyl]amine, 3′-Iminobis(N,N-dimethylpropylamine), NSC 129937, Jeffcat Z 130, Z 130, Polycat 9, N-(3-Dimethylaminopropyl)-N′,N′-dimethylpropane-1,3-diamine, Zeffcat Z 130, N,N,N′′,N′′-Tetramethyldipropylenetriamine, CT 18L, ZR 50B, PC 9, N,N,N′,N′-Tetramethyldipropylenetriamine, PC 15, (3-[[3-(Dimethylamino)propyl]amino]propyl)dimethylamine, TMDPT, 6711-48-4, 3,3'-Iminobis(N,N-dimethylpropylamine), Bis-(dimethylaminopropyl)amine, N1-(3-(Dimethylamino)propyl)-N3,N3-dimethylpropane-1,3-diamine, Bis(3-dimethylaminopropyl)amine, Tetramethyldipropylenetriamine, Bis(3-dimethylamino-1-propyl)amine, Dipropylamine, 3,3'-bis(dimethylamino)-, 2,6,10-Triazaundecane, 2,10-dimethyl-, 1,3-Propanediamine, N'-[3-(dimethylamino)propyl]-N,N-dimethyl-, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, N,N,N',N'-Tetramethyldipropylenetriamine, N-[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine, 1,3-Propanediamine,N3-[3-(dimethylamino)propyl]-N1,N1-dimethyl-, Bis[3-(dimethylamino)propyl]amine, Dipropylenetriamine, N,N,N',N'-tetramethyl-, (3-{[3-(dimethylamino)propyl]amino}propyl)dimethylamine, CW8R6R660G, DTXSID7044974, 1,3-Propanediamine, N'-(3-(dimethylamino)propyl)-N,N-dimethyl-, Bis(3-(dimethylamino)propyl)amine, NSC-129937, N'-(3-(Dimethylamino)propyl)-N,N-dimethylpropane-1,3-diamine, N'-[3-(Dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, 1,3-Propanediamine, N3-(3-(dimethylamino)propyl)-N1,N1-dimethyl-, n,n-bis[3-(dimethylamino)propyl]amine, N,N-BIS(3-(DIMETHYLAMINO)PROPYL)AMINE, EINECS 229-761-9, NSC 129937, BRN 0635876, UNII-CW8R6R660G, N'-[3-(Dimethylamino)propyl]-N,N-dimethyl-1,3-propanediamine, N-(3-(dimethylamino)propyl)-N',N'-dimethylpropane-1,3-diamine, AI3-16566, EC 229-761-9,
ZEFFCAT Z 130, Tetramethyliminobispropylamine, SCHEMBL15859, 3-04-00-00565 (Beilstein Handbook Reference), bis(dimethylaminopropyl) amine, CHEMBL28766, DTXCID5024974, 3,3 inverted exclamation marka-Iminobis(N,N-dimethylpropylamine), bis-(3-dimethylamino-propyl)-amine, STR10731, N,N-bis(3-dimethylaminopropyl)amine, Tox21_301691, MFCD00014880, NSC129937, Dipropylamine,3'-bis(dimethylamino)-, AKOS000120187, CS-W016846, N,N',N'-Tetramethyldipropylenetriamine, 2,10-Triazaundecane, 2,10-dimethyl-, NCGC00256130-01, 3,3'-Iminobis(N,N-dimethyl-propylamine),
Dipropylenetriamine,N,N',N'-tetramethyl-, CAS-6711-48-4, 3'-IMINOBIS(N,N-DIMETHYLPROPYLAMINE), FT-0656639, I0939, NS00006959, EN300-20673, 2,10-DIMETHYL-2,6,10-TRIAZAUNDECANE, 3,3'-Iminobis(N,N-dimethylpropylamine), 97%, F20331, N,N,N',N'-TETRAMETHYLIMINOBISPROPYLAMINE, 1, N'-[3-(dimethylamino)propyl]-N,N-dimethyl-, N'-[3-(Dimethylamino)propyl]-N,3-propanediamine, 1,1,9,9-TETRAMETHYL-1,5,9-TRIAZANONANE, W-104730, Q27275858, N-(3-dimethylamino-propyl)-N',N'-dimethylpropane-1,3-diamine, N,N,N',N'-tetramethyldipropylenetriamine, N,N-BIS-(3-DIMETHYLAMINOPROPYL)AMINE, 2,6,10-Triazaundecane, 2,10-dimethyl-, 3-Propanediamine,N'-[3-(dimethylamino)propyl]-N,N-dimethyl-1, Bis(3-dimethylamino-1-propyl)amine, Bis-(dimethylaminopropyl)amine, Dipropylamine, 3,3'-bis(dimethylamino)-, Dipropylenetriamine, N,N,N',N'-tetramethyl-, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, Tetramethyl dippropylene triamine, N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine, 3,3'-imino pairs (N,N-dimethyl propylamine), Tetramethyl-1,3-Propylenetriamine, tetramethyliminobispropylamine, Tetramethyl dipropylenetriamine, Bis(3-dimethylamino-1-propyl)amine, Bis-(dimethylaminopropyl)amine, Bis(3-(dimethylamino)propyl)amine, Dipropylamine, 3,3'-bis(dimethylamino)-, Dipropylenetriamine, N,N,N',N'-tetramethyl-, N,N,N',N'-Tetramethyldipropylenetriamine, N'-(3-(Dimethylamino)propyl)-N,N-dimethyl-1,3-propanediamine, 2,6,10-Triazaundecane, 2,10-dimethyl-, 3,3'-Iminobis(N,N-dimethylpropylamine), N'-[3-(dimethylamino)propyl]-N,N-dimethylpropane-1,3-diamine,



Tetramethyldipropylenetriamine is a non-emissive amine equilibrium catalyst, with slight selectivity to urea (isocyanate-water) reaction.
Tetramethyldipropylenetriamine, with the chemical formula C10H25N3, has the CAS number 6711-48-4.
Tetramethyldipropylenetriamine appears as a colorless liquid with a faint odor.
The basic structure of Tetramethyldipropylenetriamine consists of two N,N-dimethylpropylamine groups connected by an imine group.


Tetramethyldipropylenetriamine has a slight selectivity towards the urea (isocyanate-water) reaction.
Tetramethyldipropylenetriamine improves the surface cure in flexible molded systems.
Tetramethyldipropylenetriamine contains active hydrogen, so it is easy to react into the polymer matrix, so there will be no volatile emissions.


Tetramethyldipropylenetriamine is soluble in water.
Tetramethyldipropylenetriamine is also part of a group of stabilizers (Hindered Amino Stabilizers) that prevent the thermo-oxidative degradation of polypropylene.


Tetramethyldipropylenetriamine is a neutral form of the activated amine.
Tetramethyldipropylenetriamine has been shown to be biodegradable in aerobic soil environments.
Tetramethyldipropylenetriamine is also a reactive compound with functional groups that can be introduced into natural compounds.


Tetramethyldipropylenetriamine is a non-emissive balanced amine catalyst.
Due to its reactive hydrogen, Tetramethyldipropylenetriamine readily reacts into the polymer matrix.
Tetramethyldipropylenetriamine is a non-emitting amine balanced catalyst, which is slightly selective for urea (isocyanate-water) reaction.


Tetramethyldipropylenetriamine is a biochemical for proteomics research
Tetramethyldipropylenetriamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Tetramethyldipropylenetriamine contains active hydrogen, so it is easy to react into the polymer matrix, so there is no volatile emissions.
Tetramethyldipropylenetriamine improves the surface curing properties of soft molding systems, which can be used in rigid polyurethane systems requiring smooth reaction characteristics.


Tetramethyldipropylenetriamine is a colorless to yellowish transparent liquid with fishy odor.
Relative density of Tetramethyldipropylenetriamine is 0.84(20 deg C), boiling point of 220-223 deg C, freezing point -75 deg C, soluble in water, alkaline, product purity is generally greater than or equal to 99.0%.



USES and APPLICATIONS of TETRAMETHYLDIPROPYLENETRIAMINE:
Tetramethyldipropylenetriamine improves the surface curability of soft molding systems, and can be used in rigid polyurethane systems that require smooth reaction characteristics.
Tetramethyldipropylenetriamine is used in the field of pharmaceuticals.


Tetramethyldipropylenetriamine's purpose in this field involves its use as a reagent or intermediate in the synthesis of various pharmaceutical compounds.
Tetramethyldipropylenetriamine is also part of a group of stabilizers (Hindered Amino Stabilizers) that prevent the thermo-oxidative degradation of polypropylene.
The mechanism of action in pharmaceutical applications of Tetramethyldipropylenetriamine varies depending on the specific compound being synthesized.


Tetramethyldipropylenetriamine is a non-emissive amine equilibrium catalyst, with slight selectivity to urea (isocyanate-water) reaction.
Tetramethyldipropylenetriamine is a non-spray amine balanced catalyst with slight selectivity for urea (isocyanate-water) reaction.
Tetramethyldipropylenetriamine contains active hydrogen, so it is easy to react into the polymer matrix, so there is no volatile emissions.


Tetramethyldipropylenetriamine improves the surface curability of the soft molding system and can be used in a rigid polyurethane system requiring smooth reaction characteristics.
Tetramethyldipropylenetriamine is a non-emissive amine equilibrium catalyst with slight selectivity to the reaction of urea (isocyanate-water).


Tetramethyldipropylenetriamine contains active hydrogen, so it easily reacts into the polymer matrix, so there will be no volatile emissions.
Tetramethyldipropylenetriamine is used as a reagent in the synthesis of a novel class of anticancer agents called antracenylisoxazole lexitropsin conjugates.


Tetramethyldipropylenetriamine contains active hydrogen, so it is easy to react into the polymer matrix, so there will be no volatile emissions.
Tetramethyldipropylenetriamine is also part of a group of stabilizers (Hindered Amino Stabilizers) that prevent the thermo-oxidative degradation of polypropylene.


Tetramethyldipropylenetriamine improves the surface curability of soft molding systems, and can be used in rigid polyurethane systems that require smooth reaction characteristics middle.
Tetramethyldipropylenetriamine is used as a reagent in the synthesis of a novel class of anticancer agents called antracenylisoxazole lexitropsin conjugates.


Tetramethyldipropylenetriamine is also part of a group of stabilizers (Hindered Amino Stabilizers) that prevent the thermo-oxidative degradation of polypropylene.
Tetramethyldipropylenetriamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Release to the environment of Tetramethyldipropylenetriamine can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.
Tetramethyldipropylenetriamine improves the surface curability of soft molding systems, and can be used in rigid polyurethane systems that require smooth reaction characteristics.


Tetramethyldipropylenetriamine is used for spray foam insulation, flexible slabstock, packaging foam, automotive instrument panels and other application that need to improve surface cure/ reduces skinning property and improved surface appearance.
Tetramethyldipropylenetriamine is used as a reagent in the synthesis of a novel class of anticancer agents called antracenylisoxazole lexitropsin conjugates.


Tetramethyldipropylenetriamine may be used in the synthesis of dimeric quaternary alkylammonium conjugates of sterols as nitrogen containing tridentate lignand in the preparation of [3,3′-iminobis(N,N-dimethylpropylamine)](4′-methoxyflavonolato)zinc(II) perchlorate complex in the preparation of 2-[[[N,N-bis[3-(N,N-dimethylamino)propyl]amino]carbonyl]-1-methyl-4-nitropyrrole and 3-(9-anthracenyl)- N,N-bis[3-(N,N-dimethylamino)propyl]-5-methyl-4-isoxazole carboxamide


Tetramethyldipropylenetriamine is an important chemical raw materials, can be used as polyurethane catalyst, epoxy resin curing agent, epoxy accelerator and used in the synthesis of pharmaceutical intermediates and surfactants.
Tetramethyldipropylenetriamine is a reactive catalyst to promote surface curing.


Tetramethyldipropylenetriamine is mainly used as a low-odor reactive catalyst with active hydrogen group for polyurethane foam.
Tetramethyldipropylenetriamine can be used in rigid polyurethane systems where a smooth reaction profile is required.
Tetramethyldipropylenetriamine promotes the surface cure/ reduces skinning property and improved surface appearance.


Other release to the environment of Tetramethyldipropylenetriamine is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Tetramethyldipropylenetriamine is used in the following products: polymers and adhesives and sealants.
Tetramethyldipropylenetriamine is used in the following areas: mining and building & construction work.
Tetramethyldipropylenetriamine is used for the manufacture of: plastic products and machinery and vehicles.


Other release to the environment of Tetramethyldipropylenetriamine is likely to occur from: indoor use and outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives).
Tetramethyldipropylenetriamine is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay and polymers.


Tetramethyldipropylenetriamine is mainly used for molding soft and semi-rigid foam, and also used for Polyether polyurethane soft block foam and polyurethane CASE materials.
Tetramethyldipropylenetriamine is used as a reagent in the synthesis of a novel class of anticancer agents called antracenylisoxazole lexitropsin conjugates.


Release to the environment of Tetramethyldipropylenetriamine can occur from industrial use: formulation of mixtures and formulation in materials.
Tetramethyldipropylenetriamine is used in the following products: polymers, coating products and fillers, putties, plasters, modelling clay.
Tetramethyldipropylenetriamine is used in the following areas: mining and building & construction work.


Tetramethyldipropylenetriamine is used for the manufacture of: plastic products and machinery and vehicles.
Release to the environment of Tetramethyldipropylenetriamine can occur from industrial use: in the production of articles, as processing aid and as an intermediate step in further manufacturing of another substance (use of intermediates).


Release to the environment of Tetramethyldipropylenetriamine can occur from industrial use: manufacturing of the substance.
Tetramethyldipropylenetriamine is used as a reagent in the synthesis of a novel class of anticancer agents called antracenylisoxazole lexitropsin conjugates.


Tetramethyldipropylenetriamine is also part of a group of stabilizers (Hindered Amino Stabilizers) that prevent the thermo-oxidative degradation of polypropylene.
Tetramethyldipropylenetriamine is used as a corrosion inhibitor for zirconium oxide and other materials.



PROPERTIES AND USAGE OF TETRAMETHYLDIPROPYLENETRIAMINE:
Tetramethyldipropylenetriamineis a non-emissive amine equilibrium catalyst, with slight selectivity to urea (isocyanate-water) reaction.
Tetramethyldipropylenetriamine contains active hydrogen, so it is easy to react into the polymer matrix, so there will be no volatile emissions.
Tetramethyldipropylenetriamine improves the surface curability of soft molding systems, and can be used in rigid polyurethane systems that require smooth reaction characteristics.



PHYSICAL and CHEMICAL PROPERTIES of TETRAMETHYLDIPROPYLENETRIAMINE:
CAS: 6711-48-4
EINECS: 229-761-9
InChI: InChI=1/C10H25N3/c1-12(2)9-5-7-11-8-6-10-13(3)4/h11H,5-10H2,1-4H3
Molecular Formula: C10H25N3
Molar Mass: 187.33
Density: 0.841 g/mL at 25°C (lit.)
Melting Point: −78°C (lit.)
Boiling Point: 128-131°C at 20 mm Hg (lit.)
Flash Point: 209°F
Water Solubility: 425 g/L at 20°C
Vapor Pressure: 30 Pa at 20°C
Appearance: Clear liquid
Color: Colorless to Almost colorless

pKa: 10.40±0.19 (Predicted)
Storage Condition: Keep in dark place, Inert atmosphere, Room temperature
Refractive Index: n20/D 1.449 (lit.)
Density: 0.841 g/mL at 25 °C(lit.)
Boiling Point: 128-131 °C20 mm Hg(lit.)
Flash Point: 209 ºF
Melting Point: -78 °C(lit.)
Refractive index: n20D 1.449(lit.)
CAS No.: 6711-48-4
EINECS: 229-761-9
Formula: HN[(CH2)3N(CH3)2]2
Molecular Weight:187.33
Melting point: −78 °C(lit.)
Boiling point: 128-131 °C20 mm Hg(lit.)
density: 0.841 g/mL at 25 °C(lit.)

vapor pressure: 30Pa@20°C
refractive index: n20/D 1.449(lit.)
Fp: 209 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Chloroform, Methanol
form: clear liquid
pka: 10.40±0.19(Predicted)
color: Colorless to Almost colorless
Water Solubility: 425g/L@20°C
LogP: 0.214 at 21.7℃
CAS DataBase Reference: 6711-48-4(CAS DataBase Reference)
EPA Substance Registry System: 1,3-Propanediamine,
N'-[3-(dimethylamino)propyl]-N,N-dimethyl- (6711-48-4)
Physical state: liquid

Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/range: -78 °C - lit.
Initial boiling point and boiling range: 128 - 131 °C at 27 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 98 °C - closed cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available

Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 0,841 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
IUPAC Name: N-[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine
Canonical SMILES: CN(C)CCCNCCCN(C)C
InChI: InChI=1S/C10H25N3/c1-12(2)9-5-7-11-8-6-10-13(3)4/h11H,5-10H2,1-4H3
InChI Key: BXYVQNNEFZOBOZ-UHFFFAOYSA-N

Boiling Point: 114 ℃ / 15 mmHg
Flash Point: 98 °C
Purity: > 97.0 % (GC) (T)
Density: 0.841 g/mLat25 ℃(lit.)
Appearance: Colorless to brown liquid
Refractive Index: 1.45
LogP: 0.87030
XLogP3: 0.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 8
Exact Mass: 187.204847810 g/mol
Monoisotopic Mass: 187.204847810 g/mol

Topological Polar Surface Area: 18.5Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 90.3
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Melting point: −78 °C(lit.)

Boiling point: 128-131 °C20 mm Hg(lit.)
Density: 0.841 g/mL at 25 °C(lit.)
vapor pressure: 30Pa at 20℃
refractive index: n20/D 1.449(lit.)
Flash point: 209 °F
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: soluble in Chloroform, Methanol
form: clear liquid
pka: 10.40±0.19(Predicted)
color: Colorless to Almost colorless
Viscosity: 3.244mm2/s
Water Solubility: 425g/L at 20℃

LogP: 0.214 at 21.7℃
CAS DataBase Reference: 6711-48-4(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: CW8R6R660G
EPA Substance Registry System: 1,3-Propanediamine, N'-[3-(dimethylamino)propyl]-N,N-dimethyl- (6711-48-4)
IUPAC Name: N-[3-(dimethylamino)propyl]-N',N'-dimethylpropane-1,3-diamine;
Molecular Weight: 187.331g/mol
Molecular Formula: C10H25N3;
InChI: InChI=1S/C10H25N3/c1-12(2)9-5-7-11-8-6-10-13(3)4/h11H,5-10H2,1-4H3;
InChI Key: BXYVQNNEFZOBOZ-UHFFFAOYSA-N;
Complexity: 90.3
Covalently-Bonded Unit Count: 1
EC Number: 229-761-9

Exact Mass: 187.205g/mol
H-Bond Acceptor: 3
H-Bond Donor: 1
Heavy Atom Count: 13
Monoisotopic Mass: 187.205g/mol
NSC Number: 129937
Rotatable Bond Count: 8
Topological Polar Surface Area: 18.5A^2
UNII: CW8R6R660G
Molecular Formula: C10H25N3
Molecular Weight: 187.3256

InChI: InChI=1/C10H25N3/c1-12(2)9-5-7-11-8-6-10-13(3)4/h11H,5-10H2,1-4H3
CAS Registry Number: 6711-48-4
EINECS: 229-761-9
Molecular Structure: 6711-48-4 3,3'-iminobis(N,N-dimethylpropylamine)
Density: 0.863g/cm3
Boiling point: 239.4°C at 760 mmHg
Refractive index: 1.46
Flash point: 98.3°C
Vapour Pressure: 0.0402mmHg at 25°C
Molecular Weight：187.326
Exact Mass：187.33

EC Number：229-761-9
UNII：CW8R6R660G
NSC Number：129937
DSSTox ID：DTXSID7044974
HScode：2921290000
PSA：18.51000
XLogP3：0.6
Appearance：Liquid
Density：0.9±0.1 g/cm3
Melting Point：−78 °C(lit.)
Boiling Point：128-131 °C @ Press: 20 Torr
Flash Point：98.3±0.0 °C
Refractive Index：1.460

Molecular Weight: 187.33
Molecular Formula: C10H25N3
Canonical SMILES: CN(C)CCCNCCCN(C)C
InChI: InChI=1S/C10H25N3/c1-12(2)9-5-7-11-8-6-10-13(3)4/h11H,5-10H2,1-4H3
InChI Key: BXYVQNNEFZOBOZ-UHFFFAOYSA-N
Boiling Point: 114 ℃ / 15 mmHg
Flash Point: 98 °C
Purity: > 97.0 % (GC) (T)
Density: 0.841 g/mLat25 ℃(lit.)
Appearance: Colorless to brown liquid
MDL: MFCD00014880
LogP: 0.87030
Refractive Index: 1.45



FIRST AID MEASURES of TETRAMETHYLDIPROPYLENETRIAMINE:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of TETRAMETHYLDIPROPYLENETRIAMINE:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of TETRAMETHYLDIPROPYLENETRIAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of TETRAMETHYLDIPROPYLENETRIAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Tightly fitting safety goggles.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,2 mm
Break through time: 60 min
*Body Protection:
Complete suit protecting
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.



HANDLING and STORAGE of TETRAMETHYLDIPROPYLENETRIAMINE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take normal measures for preventive fire protection.
*Hygiene measures:
Wash hands before breaks and immediately after handling the product.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of TETRAMETHYLDIPROPYLENETRIAMINE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available