SYNONYMS Ethanol, 2-[2-[2-(tetradecyloxy)ethoxy]ethoxy]-, 1-(hydrogen sulfate), sodium salt (1:1);Ethanol, 2-[2-[2-(tetradecyloxy)ethoxy]ethoxy]-, hydrogen sulfate sodium salt;Ethanol, 2-[2-[2-(tetradecyloxy)ethoxy]ethoxy]-, hydrogen sulfate, sodium salt;Natrium-2-[2-[2-(tetradecyloxy)ethoxy]ethoxy]ethylsulfat;sodium 2-[2-[2-(tetradecyloxy)ethoxy]ethoxy]ethyl sulphate CAS NO:25446-80-4

SODIUM MYRISTOYL GLUTAMATE N° CAS : 38517-37-2 / 38754-83-5 / 71368-20-2 Nom INCI : SODIUM MYRISTOYL GLUTAMATE Nom chimique : Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate N° EINECS/ELINCS : 253-981-4 Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

SODIUM MYRISTOYL SARCOSINATE N° CAS : 30364-51-3 Nom INCI : SODIUM MYRISTOYL SARCOSINATE Nom chimique : Sodium N-methyl-N-(1-oxotetradecyl)aminoacetate N° EINECS/ELINCS : 250-151-3 Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Agent nettoyant : Aide à garder une surface propre Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

SODIUM MYRISTYL SULFATE N° CAS : 1191-50-0 Nom INCI : SODIUM MYRISTYL SULFATE Nom chimique : Sodium tetradecyl sulphate N° EINECS/ELINCS : 214-737-2 Classification : Sulfate Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

cas no 532-02-5 Sodium 2-naphthalenesulfonate; 2-Naphthalenesulfonic acid, sodium salt; Sodium naphthalene-2-sulphonate; Sodium beta-naphthalenesulfonate; Sodium naphthalene-6-sulfonate; beta-Naphthalenesulfonic sodium salt;

SODIUM NAPHTHALENESULFONATE; NAPHTHALENESULFONIC ACID, SODIUM SALT; Sodium naphthalenesulfonate; N° CAS : 532-02-5 / 1321-69-3; Nom INCI : SODIUM ; NAPHTHALENESULFONATE; Nom chimique : 2-Naphthalenesulfonic Acid, Sodium Salt; N° EINECS/ELINCS : 208-523-8 / 215-323-4. Ses fonctions (INCI): Hydrotrope : Augmente la solubilité d'une substance qui est peu soluble dans l'eau. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation. Noms français : B-NAPHTALENE SULFONATE DE SODIUM; SEL DE SODIUM DE L'ACIDE NAPHTALENESULFONIQUE-2; Sel de sodium de l'acide naphtalènesulfonique-2. Noms anglais : 2-NAPHTHALENESULFONIC ACID, SODIUM SALT; SODIUM .BETA.-NAPHTHALENESULFONATE; Sodium naphthalene-2-sulfonate; SODIUM NAPHTHALENE-2-SULPHONATE; 2-Naphthalenesulfonic acid, sodium salt (1:1). IUPAC names : 2-Naphthalinsulfonsäure Natriumsalz; naftalin sülfonat, naftalinsülfonat; Sodium 2-Naphthalenesulfonate; sodium naphthalene-2-sulfonate; 208-523-8 [EINECS]; 2-Naphtalènesulfonate de sodium [French]; 2-Naphthalenesulfonic Acid Sodium Salt; 2-Naphthalenesulfonic acid, sodium salt (1:1); 532-02-5 [RN]; MFCD00064186 [MDL number]; Natrium-2-naphthalinsulfonat [German] ; Natriumnaphthalen-2-sulfonat; QK3678000; Sodium 2-naphthalenesulfonate; sodium naphthalene-2-sulfonate; Sodium β-naphthalenesulfonate; [532-02-5]; 1321-69-3 [RN]; 2/5/532; 215-323-4 [EINECS]; 2-Naphthalene sulfonic acid sodium salt; 2-naphthalenesulfonate sodium;2-NAPHTHALENESULFONIC ACID SODIUM SALT,96%; 2-Naphthalenesulfonic acid, sodium salt; 2-NAPHTHALENESULFONICACIDSODIUMSALT; 2-Naphthalenesulphonic acid sodium salt; 5/2/532;EINECS 208-523-8 ; NAPHTHALENE-2-SULFONIC ACID; Naphthalene-2-sulfonic acid sodium salt; naphthalene-2-sulfonic acid, sodium salt; Naphthalene-2-sulfonic acid; sodium salt; Naphthalene-2-sulphonic acid sodium salt; Naphthalene-2-sulphonic acid, sodium salt; sodium and naphthalene-2-sulfonate; SODIUM NAPHTHALENE-2-SULPHONATE; Sodium naphthalene-2-sulphonate 95%;Sodium naphthalene-6-sulfonate; SODIUM NAPHTHALENESULFONATE; Sodium salt; Sodium salt of β-naphthalenesulfonic acid; Sodium β-naphthalenesulfonate; sodium;naphthalene-2-sulfonate ; sodium2-naphthalenesulfonate; Sodium-2-naphthalenesulfonate; TL8003494; UNII-D3F8YRX7TP; β-Naphthalenesulfonic sodium salt; Noms français : NAPHTALENE SULFONATE DE SODIUM; NAPHTHALENE SULFONIC ACID, SODIUM SALT; SEL DE SODIUM DE L'ACIDE NAPHTALENESULFONIQUE; Sel de sodium de l'acide naphtalènesulfonique; SODIUM NAPHTHALENE SULFONATE. Noms anglais : NAPHTHALENESULFONIC ACID, SODIUM SALT; Sodium naphthalenesulfonate. Utilisation: Fabrication de produits organiques; Sodium naphthalenesulphonate. ; IUPAC names :sodium naphthalene-1-sulfonate; 130-14-3 [RN]; 1-Naphtalènesulfonate de sodium [French] [ACD/IUPAC Name]; 1-Naphthalenesulfonic acid sodium salt;1-Naphthalenesulfonic acid, sodium salt; 1-Naphthalenesulfonic acid, sodium salt (1:1) [ACD/Index Name]; 215-323-4 [EINECS]; MFCD00064964 [MDL number];Natrium-1-naphthalinsulfonat [German] [ACD/IUPAC Name] ; Sodium 1-naphthalenesulfonate [ACD/IUPAC Name]; sodium naphthalene-1-sulfonate; Sodium α-naphthalenesulfonate; α-Naphthalenesulfonic acid sodium salt; [130-14-3]; [1321-69-3] ; 1321-69-3 [RN]; 1-Naphthalene Sulfonic Acid, Monosodium salt; 1-Naphthalene sulphonic acid sodium salt; 1-naphthalenesulfonic acid; sodium; 204-976-0MFCD00064964; 2-Naphthalenesulfonic Acid Sodium Salt; 2-Naphthalenesulfonic acid, sodium salt 36290-04-7 [RN] 532-02-5 [RN] 9008-63-3 [RN] 98% (dry wt.), water <5% EINECS 204-976-0 EINECS 208-523-8 EINECS 215-323-4 Naphthalene sulfonic acid, sodium salt solution Naphthalene sulfonic acid, sodium salt solution (40% or less) naphthalene-1-sulfonic acid naphthalene-1-sulfonic acid sodium salt Naphthalene-1-sulfonic acid; sodium salt Naphthalene-1-sulphonic acid sodium salt Naphthalene-1-sulphonic acid, sodium salt Naphthalene-2-sulfonic acid sodium salt naphthalenesulfonic acid sodium salt Naphthalenesulfonic acid, sodium salt Sodium ??-naphthalenesulfonate Sodium 1-naphthalenesulfonate;Sodium ??-naphthalenesulfonate Sodium 1-naphthalenesulfonate;Sodium ?-naphthalenesulfonate Sodium 2-naphthalenesulfonate [ACD/IUPAC Name] Sodium α-naphthyl acetate Sodium naphthalene sulfonate Sodium naphthalene sulfonate solution Sodium naphthalene sulfonate solution (40% or less) sodium naphthalene-2-sulfonate SODIUM NAPHTHALENE-2-SULPHONATE Sodium naphthalene-6-sulfonate SODIUM NAPHTHALENESULFONATE sodium naphthalenesulphonate Sodium salt Sodium salt of β-naphthalenesulfonic acid Sodium α-naphthalenesulfonate Sodium α-naphthalenesulfonic acid Sodium α-naphthyl acetate Sodium α-naphthylsulfonate Sodium β-naphthalenesulfonate Sodium-2-naphthalenesulfonate UNII-D3F8YRX7TP α salt α-Naphthalenesulfonic acid sodium salt β-Naphthalenesulfonic sodium salt

cas no 7631-99-4 Soda Niter; Cubic Niter; Chile Saltpeter; Sodium(I) Nitrate; Nitrate of Soda; Nitrate de sodium (French); Nitric acid sodium salt; Chile salpeter;

Sodium N-chloro-p-toluenesulfonamide is the organic compound with the formula CH3C6H4SO2NClNa.
Sodium N-chloro-p-toluenesulfonamide has a role as an antifouling biocide, a disinfectant and an allergen.


CAS Number: 127-65-1 / 7080-50-4 (trihydrate)
EC Number: 204-854-7
Molecular Formula: C7H7ClNNaO2S
Chemical formula: C7H7ClNO2S·Na / C7H7ClNO2S·Na·(3H2O) (hydrate)



SYNONYMS:
Chloramine-T, Sodium chloro(4-methylbenzene-1-sulfonyl)azanide, N-Chloro-para-toluenesulfonylamide, Sodium N-chloro-4-methylbenzenesulphonomite, Chloraseptin, Chlorazol, Clorina, Disifin, Halamid, Hydroclonazone, Trichlorol, Minachlor, Tosylchloramide Sodium, N-chlorotosylamide, sodium salt, Aseptoclean, Chloraseptine, Sodium N-chloro 4-methylbenzenesulfonamide trihydrate, Sodium N-chloro-4-toluenesulfonamide trihydrate, Sodium n-chloro-p-toluenesulfonamide trihydrate, Tosylchloramide sodium, Chloramine-T, CHLORAMINE T, 127-65-1, Chloralone, Chlorasan, Chlorazene, Chlorozone, Acti-chlore, Tosylchloramide sodium, Chloraseptine, Chlorazan, Chlorazone, Chlorosol, Chlorseptol, Heliogen, Mannolite, Tampules, Tochlorine, Tolamine, Sodium chloramine T, Monochloramine T, Multichlor, Aktivin, Sodium p-toluenesulfonchloramide, Chlorina Aktivin, Sodium chloro(tosyl)amide, Sodium tosylchloramide, Euclorina, Clorina, Tosilcloramida sodica, Tosylchloramide sodique, (N-Chloro-p-toluenesulfonamido)sodium, Sodium p-toluenesulfonylchloramide, Tosylchloramidum natricum, Berkendyl, Halamid, N-Chloro-p-toluenesulfonamide sodium, Sodium N-chloro-p-toluenesulfonamide, Anexol, chloramine-T anhydrous, Cloramine T, Gyneclorina, Clorosan, Mianine, Gansil, Chloramin Heyden, Kloramine-T, CHEBI:53767, Tosylchloramide sodium [INN], Chloramin Dr. Fahlberg, 328AS34YM6, N-Chlorotoluenesulfonamide sodium salt, NSC-36959, N-Chloro-4-methylbenzylsulfonamide sodium salt, DTXSID6040321, [chloro(p-tolylsulfonyl)amino]sodium, Aseptoclean, Desinfect, Tosylchloramid-natrium, sodium chloro(4-methylbenzenesulfonyl)azanide, Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, 149358-73-6, Tosylchloramide sodium (INN), N-Chloro-p-toluenesulfonamide sodium salt, Caswell No. 170, Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1), Chloramine-t [NF], TOSYLCHLORAMIDE SODIUM (EP IMPURITY), TOSYLCHLORAMIDE SODIUM [EP IMPURITY], TOSYLCHLORAMIDE SODIUM (EP MONOGRAPH), TOSYLCHLORAMIDE SODIUM [EP MONOGRAPH], p-Toluenesulfonchloramide Sodium Salt, sodium chloro((4-methylphenyl)sulfonyl)azanide, sodium chloro[(4-methylphenyl)sulfonyl]azanide, HSDB 4303, SR-01000872612, EINECS 204-854-7, Tosilcloramida sodica [INN-Spanish], N-Chloro-4-methylbenzenesulfonamide sodium salt, NSC 36959, Tosylchloramide sodique [INN-French], (N-chloro-p-toluenesulfonamide)sodium, Tosylchloramidum natricum [INN-Latin], AI3-18426C, EPA Pesticide Chemical Code 076502, UNII-328AS34YM6, Chloramin T, p-Toluenesulfonamide, N-chloro-, sodium salt, Tosyl chloramide sodium, Sodiumchloro(tosyl)amide, CHLORAMINE-T [MI], Epitope ID:116223, CHLORAMINE-T [HSDB], SCHEMBL19335, CHEMBL1697734, DTXCID4020321, HMS3264N19, AMY37206, BCP12015, HY-B0959, s6403, Sodium N-chloro-4-toluenesulfonamide, AKOS015890257, CCG-213937, CS-4435, TOSYLCHLORAMIDE SODIUM [WHO-DD], USEPA/OPP Pesticide Code: 076502, DA-72163, Sodium N-chloro 4-methylbenzenesulfonamide, NS00066780, sodium;chloro-(4-methylphenyl)sulfonylazanide, Chloramine-T 1000 microg/mL in Acetonitrile, EN300-75322, D02445, D88065, Q420695, J-008582, SR-01000872612-2, SR-01000872612-3, W-108379, Chloramine (T) N-Chloro-4-toluenesulfonamide,sodium salt, Z1172235461, Acti-chlore, Aktiven, Aktivin, Anexol, Asepto-Sol, Aseptoclean, Berkendyl, Chloralone, Chloramine-T, Chlorasan, Chloraseptine, Chlorazan, Chlorazene, Chlorazene Hydrosol, Chlorazone, Chlorozone, Chlorseptol, Cloramine T, Clorina, Clorosan, Desinfect, Euclorina, Gansil, Gyneclorina, Halamid, Heliogen, Kloramin, Kloramin B, Kloramine-T, Mannolite, Mianine, Monochloramine T, Multichlor, N-Chloro-4-methylbenzenesulfonamide Sodium Salt, N-Chloro-p-toluenesulfonamide Sodium, N-Chloro-p-toluenesulfonamide Sodium Salt, N-Chlorotoluenesulfonamide Sodium Salt, Sodium N-chloro-4-methylbenzenesulfonamide, Sodium N-Chloro-p-toluenesulfonamide, Sodium Chloramine T, Sodium p-Toluenesulfochloramide, Sodium p-Toluenesulfonchloramide, Sodium p-Toluenesulfonylchloramide, Sodium Tosylchloramide, Tampules, Toc, (N-Chloro-p-toluenesulfonamido)sodium, Acti-chlore, Aktivin, Anexol, Aseptoclean, Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, Berkendyl, Chloralone, Chloramin Dr. Fahlberg, Chloramin Heyden, Chloramine T, Chlorasan, Chloraseptine, Chlorazan, Chlorazene, Chlorazone, Chlorina Aktivin, Chlorosol, Chlorozone, Chlorseptol, Cloramine T, Clorina, Clorosan, Desinfect, Euclorina, Gansil, Gyneclorina, Halamid, Heliogen, Kloramin, Kloramine-T, Mannolite, Mianine, Monochloramine T, Multichlor, N-Chloro-4-methylbenzenesulfonamide sodium salt, N-Chloro-4-methylbenzylsulfonamide sodium salt, N-Chloro-p-toluenesulfonamide sodium, N-Chlorotoluenesulfonamide sodium salt, Sodium N-chloro-p-toluenesulfonamide, Sodium chloramine T, Sodium derivative of N-chloro-p-toluenesulfonamide, trihydrate, Sodium p-toluenesulfonchloramide, Sodium p-toluenesulfonylchloramide, Sodium tosylchloramide, Tampules, Tochlorine, Tolamine, Tosilcloramida sodica [INN-Spanish], Tosylchloramid-natrium, Tosylchloramide sodique [INN-French], Tosylchloramide sodium, Tosylchloramidum natricum [INN-Latin], p-Toluenesulfonamide, N-chloro-, sodium salt, [ChemIDplus] UN1759, Chloramine-T, Benzene Sulfonamide Sodium Salt , Sodium chloro(4-methylbenzenesulfonyl)azanide , N-Chloro-p-toluenesulfonamide sodium salt , Clorina, Euclorina, Tosylchloramide sodium , N-chloro tosylamide, sodium salt, N-Chloro 4-methylbenzenesulfonamide, sodium salt , sodium p-toluenesulfonchloramide, N-Chloro para-toluenesulfonylamide, EC 615-172-8, Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, Chloralone, Chlorasan, Chlorozone, chloralone, Chloramine-T, Cloramine T, tosylchloramide sodium, chloramine-t trihydrate, Sodium Chloro(tosyl)amide, Sodium N-chloro-4-methylbenzene-sulfonimidate, Chloramine-T, sodium chloro(tosyl)amide, N-Chloro-p-toluenesulfonamide Sodium Salt Trihydrate, Tosylchloramide Sodium Trihydrate, (N-Chloro-p-toluenesulfonamido)sodium Trihydrate, N-chloro-4-methylbenzenesulfonamide Sodium Salt Trihydrate



Sodium N-chloro-p-toluenesulfonamide is an organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.
Sodium N-chloro-p-toluenesulfonamide has a role as an antifouling biocide, a disinfectant and an allergen.
Sodium N-chloro-p-toluenesulfonamide contains a chloro(p-tolylsulfonyl)azanide.


Sodium N-chloro-p-toluenesulfonamide is the organic compound with the formula CH3C6H4SO2NClNa.
Both the anhydrous salt and Sodium N-chloro-p-toluenesulfonamide's trihydrate are known.
Both are white powders.


Sodium N-chloro-p-toluenesulfonamide is used as a reagent in organic synthesis.
Sodium N-chloro-p-toluenesulfonamide is commonly used as cyclizing agent in the synthesis of aziridine, oxadiazole, isoxazole and pyrazoles.
Sodium N-chloro-p-toluenesulfonamide's inexpensive, has low toxicity and acts as a oxidizing agent.


In addition, Sodium N-chloro-p-toluenesulfonamide also acts as a source of nitrogen anions and electrophilic cations.
Sodium N-chloro-p-toluenesulfonamide may undergo degradation on long term exposure to atmosphere such that care must be taken during its storage.
Sodium N-chloro-p-toluenesulfonamide is an organic sodium salt derivative of toluene-4-sulfonamide with a chloro substituent in place of an amino hydrogen.


Sodium N-chloro-p-toluenesulfonamide is a white or slightly yellow crystals or crystalline powder.
Sodium N-chloro-p-toluenesulfonamide is one of numerous organometallic compounds manufactured.
Organometallics are useful reagents, catalysts, and precursor materials with applications in thin film deposition, industrial chemistry, pharmaceuticals, LED manufacturing, and others.


Sodium N-chloro-p-toluenesulfonamide, known as Chloramine-T (CAT), is a low-cost mild oxidizing agent with a wide range of uses.
Sodium N-chloro-p-toluenesulfonamide acts as a source of halonium cation and nitrogen anion and thus acts as base and nucleophile.
Sodium N-chloro-p-toluenesulfonamide reacts with a wide range of functional groups and carries different molecular transformations.


Sodium N-chloro-p-toluenesulfonamide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.
Sodium N-chloro-p-toluenesulfonamide is the organic compound with the formula CH3C6H4SO2NClNa.


Both the anhydrous salt and Sodium N-chloro-p-toluenesulfonamide's trihydrate are known.
Both are white powders.
Sodium N-chloro-p-toluenesulfonamide's inexpensive, has low toxicity and acts as a oxidizing agent.


In addition, Sodium N-chloro-p-toluenesulfonamide also acts as a source of nitrogen anions and electrophilic cations.
Sodium N-chloro-p-toluenesulfonamide may undergo degradation on long term exposure to atmosphere such that care must be taken during its storage.
Sodium N-chloro-p-toluenesulfonamide is a disinfectant that is used to treat wastewater and as a preservative for water.


Sodium N-chloro-p-toluenesulfonamide has been shown to be effective against bacteria, fungi, and viruses.
Sodium N-chloro-p-toluenesulfonamide is an antimicrobial agent that reacts with the matrix in which it is applied to form chloramines-T (NHClO).
Sodium N-chloro-p-toluenesulfonamide inhibits the activity of enzymes such as those involved in DNA synthesis and protein synthesis.


This reaction also generates an electric current due to the redox potentials of the reactants.
The presence of aziridines in Sodium N-chloro-p-toluenesulfonamide leads to crosslinking between proteins, which enhances its effectiveness as a disinfectant.


Sodium N-chloro-p-toluenesulfonamide has been shown to have no adverse effects on human erythrocytes or DNA when used at concentrations up to 100 µg/mL.
Sodium N-chloro-p-toluenesulfonamide is a white crystal powder.
Sodium N-chloro-p-toluenesulfonamide has a slight smell of chlorine gas, no bitterness, and slowly decomposes in the exposed air.


The effective chlorine is reduced by 0.1% in one year, gradually loses chlorine and turns yellow, is easily soluble in water and ethanol, and is insoluble in chloroform, ether or benzene.
Sodium N-chloro-p-toluenesulfonamide is a white to yellow crystals with a slight odor of Chlorine.


Sodium N-chloro-p-toluenesulfonamide is a titrimetric reagent, and an oxidizing agent.
Sodium N-chloro-p-toluenesulfonamide is an investigational animal drug used in the aquaculture industry and also is a very effective odor control compound.



USES and APPLICATIONS of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
Sodium N-chloro-p-toluenesulfonamide is used reagent in amidohydroxylation
Sodium N-chloro-p-toluenesulfonamide is used the Sharpless oxyamination converts an alkene to a vicinal aminoalcohol.
Sodium N-chloro-p-toluenesulfonamide is used a common source of the amido component of this reaction is chloramine-T.


Vicinal aminoalcohols are important products in organic synthesis and recurring pharmacophores in drug discovery.
Sodium N-chloro-p-toluenesulfonamide is used the Sharpless oxyamination and Oxidant.
Sodium N-chloro-p-toluenesulfonamide is a strong oxidant.


Sodium N-chloro-p-toluenesulfonamide oxidizes hydrogen sulfide to sulfur and mustard gas to yield a harmless crystalline sulfimide.
Sodium N-chloro-p-toluenesulfonamide converts iodide to iodine monochloride (ICl).
ICl rapidly undergoes electrophilic substitution predominantly with activated aromatic rings, such as those of the amino acid tyrosine.


Thus, Sodium N-chloro-p-toluenesulfonamide is used to incorporate iodine into peptides and proteins.
Sodium N-chloro-p-toluenesulfonamide together with iodogen or lactoperoxidase is commonly used for labeling peptides and proteins with radioiodine isotopes.
This disinfectant is for external use only, Sodium N-chloro-p-toluenesulfonamide can exterminate bacteria, viruses, fungi, spore.


The action principle is that chlorine can sterilize slowly and lastingly, and also can dissolve necrotic tissue, chlorine come from hypochlorous acid which is produced by Sodium N-chloro-p-toluenesulfonamide solution.
Sodium N-chloro-p-toluenesulfonamide is used apply to disinfect drinking water container,food,all kind of tableware, fruits and vegetables,and cleaning wound, mucous membrane.


Sodium N-chloro-p-toluenesulfonamide is used in preparation of Acetoxy Chloro Me Butene.
Most importantly, Sodium N-chloro-p-toluenesulfonamide can be used in acidic, neutral, and basic conditions.
As a result, Sodium N-chloro-p-toluenesulfonamide’s been widely used in chemistry, particularly in organic synthesis and analytical chemistry.


Sodium N-chloro-p-toluenesulfonamide is used in formulation or re-packing and at industrial sites.
Sodium N-chloro-p-toluenesulfonamide is being reviewed for use as a biocide in the EEA and/or Switzerland, for: disinfection, veterinary hygiene, food and animals feeds, drinking water.


Sodium N-chloro-p-toluenesulfonamide is used in the following products: washing & cleaning products.
Release to the environment of Sodium N-chloro-p-toluenesulfonamide can occur from industrial use: formulation in materials.
Sodium N-chloro-p-toluenesulfonamide is used in the following products: washing & cleaning products.


Release to the environment of Sodium N-chloro-p-toluenesulfonamide can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.
Sodium N-chloro-p-toluenesulfonamide is used as a reagent in organic synthesis.


Sodium N-chloro-p-toluenesulfonamide is commonly used as cyclizing agent in the synthesis of aziridine, oxadiazole, isoxazole and pyrazoles.
Sodium N-chloro-p-toluenesulfonamide is a disinfectant with broad-spectrum bactericidal ability for external use.
Sodium N-chloro-p-toluenesulfonamide contains 24 to 25% of available chlorine.


Sodium N-chloro-p-toluenesulfonamide is relatively stable and has a killing effect on bacteria, viruses, fungi and spores.
The principle of action is that the solution produces hypochlorous acid to release chlorine, which has a slow and long-lasting bactericidal action and can dissolve necrotic tissue.


Sodium N-chloro-p-toluenesulfonamide has mild and long-lasting effect, no irritation to mucous membranes, no side effects, and excellent effect.
Sodium N-chloro-p-toluenesulfonamide is often used for washing and disinfecting wounds and ulcers.
Sodium N-chloro-p-toluenesulfonamide is widely used in the sterilization of sterile rooms and disinfection of medical devices in pharmaceutical companies.


Sodium N-chloro-p-toluenesulfonamide is also used for food utensils, fruit and vegetable breeding industry disinfection, wound surface, mucous membrane washing.
Sodium N-chloro-p-toluenesulfonamide was originally used as a bleach in a manner similar to Chloramine B.


Sodium N-chloro-p-toluenesulfonamide is now primarily used as an Disinfectant and Fungicide.
Sodium N-chloro-p-toluenesulfonamide is used as a bleaching agent and oxidizing desizing agent in the printing and dyeing industry, used as a reagent for supplying chlorine.


Sodium N-chloro-p-toluenesulfonamide has other applications that include: algaecide, bactericide, germicide, parasite control, and for drinking water disinfection.
Sodium N-chloro-p-toluenesulfonamide is also highly effective against bacteria, viruses, and spores.


In the aquaculture and aquafarming industries, Sodium N-chloro-p-toluenesulfonamide (Tosylchloramide Sodium Salt) is used to treat external bacterial infections in salmonid fish such as koi, salmon, trout, and whitefish.
In the personal care industry, Sodium N-chloro-p-toluenesulfonamide is used in hydrotherapy treatments to revitalize, maintain, and restore health.


Hydrotherapeutic applications of Sodium N-chloro-p-toluenesulfonamide include whirlpools, saunas, steam baths, foot baths, and sitz baths.
Sodium N-chloro-p-toluenesulfonamide is also used for disinfection in saunas, solariums, gyms, sport centres, kitchens, sanitary facilities, and air conditioning units.


As an anti-microbial agent, Sodium N-chloro-p-toluenesulfonamide it has had widespread use in a broad range of practices, including medical, dental, verterinary food processing and agricultural.
Sodium N-chloro-p-toluenesulfonamide also has been used in direct contact with tissues because it has a low degree of cytotoxicity.



REACTIONS OF SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
Sodium N-chloro-p-toluenesulfonamide contains active (electrophilic) chlorine.
Sodium N-chloro-p-toluenesulfonamide's reactivity is similar to that of sodium hypochlorite.

Aqueous solutions of Sodium N-chloro-p-toluenesulfonamide are slightly basic (pH typically 8.5).
The pKa of the closely related N-chlorophenylsulfonamide C6H5SO2NClH is 9.5.

Sodium N-chloro-p-toluenesulfonamide is prepared by oxidation of toluenesulfonamide with sodium hypochlorite, with the latter being produced in situ from sodium hydroxide and chlorine (Cl2).



PHYSICAL and CHEMICAL PROPERTIES of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 226.9783716 g/mol
Monoisotopic Mass: 226.9783716 g/mol
Topological Polar Surface Area: 43.5Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 231
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Chemical formula: C7H7ClNO2S·Na
C7H7ClNO2S·Na·(3H2O) (hydrate)
Molar mass: 227.64 g/mol
281.69 g/mol (trihydrate)
Appearance: White powder
Density: 1.4 g/cm3
Melting point Releases chlorine at 130 °C (266 °F; 403 K)
Solid melts at 167–169 °C
Solubility in water >100 mg/mL (hydrate)
Molecular Weight: 227.64

Appearance: Solid
Formula: C7H7ClNNaO2S
CAS No.: 127-65-1
SMILES: O=S(C1=CC=C(C)C=C1)(N([Na])Cl)=O
Shipping: Room temperature in continental US; may vary elsewhere.
Storage: 4°C, sealed storage, away from moisture
Appearance: White Powder
Purity: ≥99%
Active Chlorine: ≥24.5%
PH: 8.0-11.0
Physical state: solid
Color: No data available
Odor: No data available

Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available

Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Water Solubility: 1.52 mg/mL
logP: -1
logP: 1.85
logS: -2.2

pKa (Strongest Acidic): 4.89
Physiological Charge: -1
Hydrogen Acceptor Count: 3
Hydrogen Donor Count: 0
Polar Surface Area: 43.37 Å2
Rotatable Bond Count: 1
Refractivity: 47.79 m3·mol-1
Polarizability: 18.65 Å3
Number of Rings: 1
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: No
MDDR-like Rule: No

Chemical Formula: C7H7ClNO2S·Na
Hydrate Formula: C7H7ClNO2S·Na·(3H2O)
Molecular Weight:
227.64 g/mol (anhydrous)
281.69 g/mol (trihydrate)
Appearance: White powder
Density: 1.4 g/cm³
Melting Point:
Releases chlorine at 130 °C (266 °F; 403 K)
Solid melts at 167–169 °C
Solubility in Water: >100 g/L (hydrate)
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1

Exact Mass: 226.9783716 g/mol
Monoisotopic Mass: 226.9783716 g/mol
Topological Polar Surface Area: 43.5 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 231
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Chemical Name: Sodium; chloro-(4-methylphenyl)sulfonylazanide
Compound Formula: C7H7ClNNaO2S
Molecular Weight: 227.644 g/mol
Appearance: White powder or crystals
Density: 1.4 g/cm³
Melting Point: 167-170 °C
Boiling Point: 314.3 °C at 760 mmHg (est.)
Flash Point: 143.9 °C (291.00 °F, TCC)
Solubility in Water: >100 mg/mL (est.)
Exact Mass: 226.978378 g/mol
Monoisotopic Mass: 226.978378 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4

Rotatable Bond Count: 1
Topological Polar Surface Area: 42.52 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 231
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
InChI Identifier: InChI=1S/C7H7ClNO2S.Na/c1-6-2-4-7(5-3-6)12(10,11)9-8;/h2-5H,1H3;/q-1;+1
InChI Key: VDQQXEISLMTGAB-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1)S(=O)(=O)[N-]Cl.[Na+]
EC Number: 204-854-7
PubChem CID: 3641960

RTECS Number: XT5616800
Assay: 95.00 to 100.00%
Food Chemicals Codex Listed: No
Vapor Pressure: 0.000472 mmHg @ 25 °C (est.)
logP (o/w): 2.268 (est.)
Stability: Stable.
Incompatible with strong oxidizing agents.
May decompose violently if heated above 130 °C.
May decompose on exposure to air.
Storage: Keep container tightly closed in a dry and well-ventilated place



FIRST AID MEASURES of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of SODIUM N-CHLORO-P-TOLUENESULFONAMIDE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

SYNONYMS Soda Niter; Cubic Niter; Chile Saltpeter; Sodium(I) Nitrate Nitrate of Soda CAS NO7631-99-4

Sodium nitrite is an inorganic compound with the chemical formula NaNO2.
Sodium nitrite is white or yellow patch on the orthorhombic crystal or powder.
Sodium nitrite is soluble in water and liquid ammonia, its aqueous solution is alkaline.

CAS Number: 7632-00-0
Molecular Formula: NaNO2
Molecular Weight: 69
EINECS Number: 231-555-9

Sodium nitrite is an inorganic compound with the chemical formula NaNO2.
Sodium nitrite is a white to slightly yellowish crystalline powder that is very soluble in water and is hygroscopic.
From an industrial perspective, Sodium nitrite is the most important nitrite salt.

Sodium nitrite is a precursor to a variety of organic compounds, such as pharmaceuticals, dyes, and pesticides, but it is probably best known as a food additive used in processed meats and (in some countries) in fish products.
Sodium nitrite is similar in name and use to sodium nitrate.
Both are preservatives used in processed meats, such as salami, hot dogs, and bacon.

Sodium nitrite has been synthesized by several chemical reactions that involve the reduction of sodium nitrate.
Industrial production of sodium nitrite is primarily by the absorption of nitrogen oxides into aqueous sodium carbonate or sodium hydroxide.
Over the years, sodium nitrite has raised some concerns about its safety in foods, but it remains in use and there are indications that it may actually be healthy.

Sodium nitrite was developed during the 1960s.
In 1977, the US Department of Agriculture (USDA) considered banning it but the USDA’s final ruling on the additive came out in 1984, allowing its use.
Studies in the 1990s indicated some adverse effects of sodium nitrite, for instance the potential to cause childhood leukemia and brain cancers.

In the late 1990s, the National Toxicity Program (NTP) began a review of sodium nitrite and proposed listing sodium nitrite as a developmental and reproductive toxicant, but a report in 2000 by NTP proposed that sodium nitrite is not a toxic substance and removed it from the list of developmental and reproductive toxicants.
Sodium nitrite is now believed that it can help with organ transplants and leg vascular problems, while preventing heart attacks and sickle cell disease.
Sodium nitrite (NaNO2) is an inorganic compound that is commonly used as a reagent and catalyst in synthetic organic chemistry.

Chemical formula Sodium nitrite is NaNO2, in which N has a valency is + III.
Sodium nitrite is colorless or yellow crystal, the relative density is 2.168 (0℃), the melting point is 271℃, and it is decomposed when 320℃.
Sodium nitrite is soluble in water, and aqueous solution is alkaline because of nitrate hydrolysis.

Sodium nitrite has the characteristics of reduction and oxidation and is mainly oxidation.
In acidic solution, the main performance is oxidation.
In alkaline solution or in case of strong oxidizing agent, its performance is reduction.

With sulfur, phosphorus, organic matter and other friction or impact can cause combustion or explosion.
Sodium nitrite can be placed in the air with the oxygen reaction, and gradually produce sodium nitrate: NaNO2+1/2O2=NaNO3.
When using strong acidic sodium nitrite, it can be nitrited to nitric acid.

Nitrite is very unstable, easily decomposed into nitrogen dioxide, nitric oxide and water.
The nitrogen atoms and oxygen atoms all have a single pair of electrons, which can be used as ligands, and can be used as ligands to form complexes with many metal ions.
Sodium nitrite is toxic, carcinogenic substances, using it must be attention.

Sodium nitrite is used in printing and dyeing industry and organic synthesis.
Sodium nitrite is obtained by the reaction of sodium nitrate and lead in a total of hot condtion.
NaNO3+Pb=NaNO2+PbO.

The reaction mixture obtained by hot water treatment, filtration to remove insoluble lead oxide, concentration and crystallization of sodium nitrite crystal can be obtained.
Sodium nitrite is an inorganic sodium salt having nitrite as the counterion.
Sodium nitrite is used as a food preservative and antidote to cyanide poisoning.

Sodium nitrite has a role as an antimicrobial food preservative, an antihypertensive agent, a food antioxidant, a poison and an antidote to cyanide poisoning.
Sodium nitrite is a nitrite salt and an inorganic sodium salt.
Sodium nitrite is a white crystalline powder.

If someone ingests enough of this substance, it can interfere with the body’s red blood cell’s ability to transport oxygen.
This dangerous and potentially fatal condition is called methemoglobinemia.
Sodium nitrite is a yellowish white crystalline solid.

Noncombustible but will accelerate the burning of combustible material.
If large quantities are involved in a fire or if the combustible material is finely divided, an explosion may result.
If contaminated by ammonium compounds, spontaneous decomposition can occur and the resulting heat may ignite surrounding combustible material.

Prolonged exposure heat may result in an explosion.
Toxic oxides of nitrogen are produced in fires involving Sodium nitrite.
Sodium nitrite is used as a food preservative, and to make other chemicals.

Sodium nitrite is also found at low concentrations in most vegetables.
Spinach and lettuce can have some of the highest concentrations but all vegetables will contain some levels of sodium nitrite.
Sodium nitrite has been explored in human and veterinary medicines as a vasodilator, reducing blood pressure, and is also used as an antidote for cyanide poisoning.

Sodium nitrite, NaN02, is a fire-hazardous, air-sensitive, yellowish white powder that is soluble in water and decomposes at temperatures above 320°C (608 °F).
Sodium nitrite is used as an intermediate for dye stuffs and for pickling of meat, in dyeing of textiles, in rustproofing, in medicine, and as a reagent in organic chemistry.
Sodium nitrite is also able to effectively delay the development of oxidative rancidity.

Lipid peroxidation is considered to be a major reason for the deterioration of quality of meat products (rancidity and unappetizing flavors).
Sodium nitrite acts as an antioxidant in a mechanism similar to the one responsible for the coloring effect.
Nitrite reacts with heme proteins and metal ions, neutralizing free radicals by nitric oxide (one of its byproducts).

Neutralization of these free radicals terminates the cycle of lipid oxidation that leads to rancidity.
Sodium nitrite is the most important cure additive responsible for the typical colour and flavour associated with cooked cured meats.
Sodium nitrite provides oxidative stability to meat while helping control the flavour and prevent the growth of C. botulinum, especially in regard to mishandling and temperature abuse.

Sodium nitrate is used in dry cured meat, because it slowly breaks down into nitrite.
Adding nitrite to food can lead to the formation of small amounts of potent cancer-causing chemicals (nitrosamines), particularly in fried bacon.
Nitrite, which also occurs in saliva and forms from nitrate in several vegetables, can undergo the same chemical reaction in the stomach.

Sodium nitrite looks like an oversized grain of salt, according to a 2017 database entry from the International Programme on Chemical Safety.
Most cured meat products feature this food additive, according to a March 2012 paper in Meat Science.
Adding a small amount of sodium nitrite turns foods like hot dogs slightly pink.

Sodium nitrates (NaNO3) and sodium nitrites (NaNO2) are naturally occurring chemical compounds commonly used in cured meat products such as bacon and hot dogs.
For home cooks, a product called "pink salt" or Prague powder that combines sodium nitrites and/or nitrates with sodium chloride (salt) makes it possible to safely preserve meat for flavor and extended storage.
Sodium nitrite is a type of salt that happens to be particularly effective as a food preservative.

A naturally occurring mineral, Sodium nitrite is present in all kinds of vegetables (root veggies such as carrots and leafy greens such as celery and spinach), along with many fruits and grains.
Anything that grows from the ground draws Sodium nitrite out of the soil.
Sodium nitrite has a long and somewhat complicated history.

Sodium nitrite was first developed in the 1960s, and in 1977 the USDA considered banning it, but in 1984 its use as a food additive was allowed.
Studies in the 1990s indicated that there could be adverse effects linked to the use of sodium nitrite as a food additive, and the National Toxicity Program (NTP) recommended listing the compound as a developmental and reproductive toxicant.
However, in a report by the NTP in 2000, sodium nitrite was found to not be a toxic substance when used at approved levels and was removed from the list of developmental and reproductive toxicants.

Today, it is believed that sodium nitrite could prevent heart attacks and sickle cell disease and help with organ transplants and vascular problems in the legs.
Sodium nitrite is used in many products and industrial processes, including heat transfer salts, metal treatment and finishing, meat and fish preservatives, pharmaceuticals, and as an antidote to cyanide poisoning.

Sodium nitrite is a white or white-yellowish hygroscopic solid, soluble in water and slightly soluble in primary alcohols, while insoluble in alkanes and chlorocarbons.
Sodium nitrite has a density of 2.168 g/cm3.
Sodium nitrite melts when heated to 271 °C, and will also decompose, with significant decomposition starting above 320 °C.

Melting point: 271 °C (lit.)
Boiling point: 320 °C
Density: 2.17g/cm3
storage temp.: 2-8°C
solubility: aqueous acid: 1 - 2μl acetic acid per ml H2Osoluble
form: powder
color: White or colorless
Specific Gravity: 2.168
Odor: Odorless
PH Range: 9
PH: 9 (100g/l, H2O, 20℃)
Oxidising Properties: The substance or mixture is classified as oxidizing with the subcategory 3
Water Solubility: 820 g/L (20 ºC)
Sensitive: Hygroscopic
Merck: 14,8648

Sodium nitrite is an oxidizing agent. Mixtures with phosphorus, tin(II) chloride or other reducing agents may react explosively.
If contaminated by ammonium compounds, spontaneous decomposition can occur and resulting heat may ignite surrounding combustible material.
Reacts with acids to form toxic nitrogen dioxide gas.

Mixing with liquid ammonia forms dipotassium nitrite, which is very reactive and easily explosive.
Melting together wilh an ammonium salt leads to a violent explosion.
A mixture with potassium cyanide may cause an explosion.

Noncombustible but accelerates the burning of all combustible material.
If large quantities are involved in fire or if the combustible material is finely divided, an explosion may result.
When a little ammonium sulfate is added to fused potassium nitrite, a vigorous reaction occurs attended by flame

The appearance and taste of meat is an important component of consumer acceptance.
Sodium nitrite is responsible for the desirable red color (or shaded pink) of meat.
Very little nitrite is needed to induce this change.

Sodium nitrite has been reported that as little as 2 to 14 parts per million (ppm) is needed to induce this desirable color change.
However, to extend the lifespan of this color change, significantly higher levels are needed.
The mechanism responsible for this color change is the formation of nitrosylating agents by nitrite, which has the ability to transfer nitric oxide that subsequently reacts with myoglobin to produce the cured meat color.

The unique taste associated with cured meat is also affected by the addition of sodium nitrite.
However, the mechanism underlying this change in taste is still not fully understood.
In conjunction with salt and pH levels, sodium nitrite reduces the ability of Clostridium botulinum spores to grow to the point of producing toxin.

Some dry-cured meat products are manufactured without nitrites.
For example, Parma ham, which has been produced without nitrite since 1993, was reported in 2018 to have caused no cases of botulism.
Sodium nitrite has shown varying degrees of effectiveness for controlling growth of other spoilage or disease causing microorganisms.

Although the inhibitory mechanisms are not well known, its effectiveness depends on several factors including residual nitrite level, pH, salt concentration, reductants present and iron content.
The type of bacteria also affects sodium nitrite's effectiveness.
It is generally agreed that sodium nitrite is not effective for controlling Gram-negative enteric pathogens such as Salmonella and Escherichia coli.

Other food additives (such as lactate and sorbate) provide similar protection against bacteria, but do not provide the desired pink color.
Nitrites do not occur naturally in vegetables in significant quantities.[45] Boiling vegetables does not affect nitrite levels.
The presence of nitrite in animal tissue is a consequence of metabolism of nitric oxide, an important neurotransmitter.

Nitric oxide can be created de novo from nitric oxide synthase utilizing arginine or from ingested nitrite.
In organic synthesis isotope enriched sodium nitrite-15N can be used instead of normal sodium nitrite as their reactivity is nearly identical in most reactions.
The obtained products carry isotope 15N and hence nitrogen NMR can be efficiently carried out.

Sodium nitrite has gained attractiveness through online suicide forums.
These forums share information on how to obtain sodium nitrite and even step-by-step instructions on how to use it for suicide. Local poison centers have records that explicitly state that patients researched this method of suicide in an online blog or forum.
The records also show that half of these patients obtained sodium nitrite online.

Sodium Nitrite is an inorganic compound.
Sodium nitrite is a white to slightly yellowish crystalline powder that is very soluble in water.
Sodium nitrite is used as a food preservative and antidote to cyanide poisoning.

Sodium nitrite is similar in name and used to sodium nitrate.
Both are preservatives used in processed meats, such as salami, hot dogs, and bacon.
Sodium Nitrite is a powerful oxidizing agent which is used as a preservative due to its ability to prevent the bacteria from colonizing the food.

Sodium Nitrite consists of a sodium cation (Na+) and a nitrite anion (NO2– ).
To write the formula of Sodium Nitrite go to the periodic table Sodium is a chemical element with the symbol Na with atomic number 11.
Sodium is a metal and the nitrate ion NO2– is a group of nonmetals.

Sodium in group I has a 1+ ionic charge (Na+1).
Nitrite has a 1- charge (NO2–).
Sodium Nitrite is an inorganic compound with the chemical formula NaNO2.

In this structure, an alkali sodium atom is attached to the nitrite anion; according to Lewis structure in this nitrite anion is more stable; in this nitrite anion, a two resonance hybrid structure is possible.
Sodium nitrite is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning.
Sodium nitrite is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.

There is also research to investigate its applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and Pseudomonas aeruginosa infections.
Sodium nitrite and sodium thiosulfate injection are used together to treat cyanide poisoning.
Cyanide poisoning is a life-threatening condition that requires immediate medical attention.

Sodium nitrite is more likely to occur if you breathe smoke from closed-space household and industrial fires, or you have swallowed or breathe cyanide (a chemical poison), or your skin is exposed to cyanide.
Sodium nitrite is a white to yellowish crystalline powder, highly soluble in water it is available as both solid and solution.
Sodium nitrite is a highly effective corrosion inhibitor found in closed loop circuits and as an additive in industrial lubricants.

Sodium nitrite is also a chemical reagent used to manufacture products in the textile and rubber manufacturing industries.
In food, sodium nitrite is an antimicrobial salt used in the curing process of a number of meats, inhibiting the growth of bacteria and preventing spoilage.
Sodium nitrite also helps to give meats their colour and enhances flavour. Commonly known as food additive number E250, it is effective at inhibiting botulism-causing bacteria in processed meat, fish and vegetables.

Production Of Sodium nitrite:
Sodium nitrite may be prepared by the thermal decomposition of sodium nitrate, but the reduction of nitrate is usually effected by stirring lead parings or copper filings into the molten salt:
NaNO3+ Pb →PbO + NaNO2
After cooling, the mass is extracted with hot water,filtered and sodium nitrite crystallized after evaporation to small bulk.

Industrially，sodium nitrite is formed by the action of nitrogen oxide (nitric oxide) and nitrogen dioxide together, obtained by the catalytic oxidation of ammonia, on sodium hydroxide or sodium carbonate solutions:
NO+NO2+2OH- →2NO2-+ HO

Sodium nitrite, yellowish-white solid, soluble, formed (1) by reaction of nitric oxide plus nitrogen dioxide and sodium carbonate or hydroxide, and then evaporating, (2) by heating sodium nitrate and lead to a high temperature, and then extracting the soluble portion (lead monoxide insoluble) with H2O and evaporating.
Used as an important reagent (diazotizing) in organic chemistry.

Industrial production of sodium nitrite follows one of two processes, the reduction of nitrate salts, or the oxidation of lower nitrogen oxides.
One method uses molten sodium nitrate as the salt, and lead which is oxidized, while a more modern method uses scrap iron filings to reduce the nitrate.
A more commonly used method involves the general reaction of nitrogen oxides in alkaline aqueous solution, with the addition of a catalyst.

The exact conditions depend on which nitrogen oxides are used, and what the oxidant is, as the conditions need to be carefully controlled to avoid over oxidation of the nitrogen atom.
Sodium nitrite has also been produced by reduction of nitrate salts by exposure to heat, light, ionizing radiation, metals, hydrogen, and electrolytic reduction.

Uses:
Sodium nitrite is a commonly used meat preservative, particularly in cured meats such as ham, hot dogs, sausages, and bacon.
The nitrite ion inhibits the growth of bacteria, particularly Clostridium botulinum, an organism that produces the deadly botulism toxin.
Sodium nitrite is also used to treat packages of red meat, such as beef.

Blood exposed to the air rapidly produces a brown color, but shoppers much prefer their meat purchases to look bright red.
Thus,the meat is treated with sodium nitrite; the nitrite ion is reduced to nitrogen monoxide, which then reacts with the hemoglobin to form a very stable bright red compound.
Sodium nitrite is true that the nitrite will prevent bacterial growth in this circumstance as well, but these days, the meat is kept at temperatures low enough to inhibit bacteria.

To persuade shoppers to prefer brownish rather than red meat will require a lot of re-education.
Now that all meats are treated with sodium nitrite, there is concern that the cooking process will cause the nitrite ion to react with amines in the meat to produce nitrosamines,compounds containing the -NNO functional group.

These compounds are known to be carcinogenic.
However, as long as preserved meats are consumed in moderation, it is generally believed that the cancer risk is minimal.

Sodium nitrite is used to fix the colors in preserved fish and meats.
Sodium nitrite is also important(along with sodium chloride) in controlling the bacterium Clostridium botulinum, which causes botulism.
Lunch meats, hams, sausages, hot dogs, and bacon are usually preserved this way.

In medicines, Sodium nitrite is a vasodilator, intestinal relaxant, bronchodilator, and an antidote to cyanide and hydrogen sulfide poisoning.
Sodium nitrite is produced in the human body by the action of saliva on sodium nitrate, and is important in controlling bacteria in the stomach, to prevent gastroenteritis.
The body produces more sodium nitrite than is consumed in food.

Sodium nitrite can react with proteins in the stomach or during cooking, especially in high heat (such as frying bacon), to form carcinogenic N-nitrosamines.
To prevent this, ascorbic acid or erythorbic acid is commonly added to cured meats.
Manufacture of diazo dyes, nitroso Compounds, and in many other processes of manufacture of organic chemicals; dyeing and printing textile fabrics; bleaching flax, silk, and linen.

Sodium Nitrite is the salt of nitrous acid that functions as an antimicrobial agent and preservative.
Sodium nitrite is a slightly yellow granular powder or nearly white, opaque mass or sticks.
Sodium nitrite is deliquescent in air.

Sodium nitrite has a solubility of 1 g in 1.5 ml of water.
Sodium nitrite is used in meat curing for color fixation and development of flavor.
The main use of sodium nitrite is for the industrial production of organonitrogen compounds.

Sodium nitrite is a reagent for conversion of amines into diazo compounds, which are key precursors to many dyes, such as diazo dyes.
Nitroso compounds are produced from nitrites.
These are used in the rubber industry.

Sodium nitrite is used in a variety of metallurgical applications, for phosphatizing and detinning.
Sodium nitrite is an effective corrosion inhibitor and is used as an additive in industrial greases, as an aqueous solution in closed loop cooling systems, and in a molten state as a heat transfer medium.
Sodium nitrite is used for a variety of reasons.

Sodium nitrite’s a common preservative often used in cured meat to preserve its shelf life.
Sodium nitrite can also be used for automotive maintenance, animal control, and as part of the treatment for severe cases of cyanide poisoning.
Sodium nitrite is used in the following products: hydraulic fluids, lubricants and greases, heat transfer fluids, metal working fluids and anti-freeze products.

Sodium nitrite is used in the following areas: offshore mining.
Sodium nitrite is used for the manufacture of: chemicals, fabricated metal products and machinery and vehicles.
Release to the environment of Sodium nitrite can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and in the production of articles.

Sodium nitrite is used to speed up the curing of meat, inhibit the germination of Clostridium botulinum spores, and also impart an attractive pink color.
Nitrite reacts with the meat myoglobin to cause color changes, first converting to nitrosomyoglobin (bright red), then, on heating, to nitrosohemochrome (a pink pigment).
Historically, Sodium nitrite has been used for the preservation of meat.

The salt-preserved meat product was usually brownish-gray in color.
When sodium nitrite is added with the salt, the meat develops a red, then pink color, which is associated with cured meats such as ham, bacon, hot dogs, and bologna.
In the early 1900s, irregular curing was commonplace.

This led to further research surrounding the use of sodium nitrite as an additive in food, standardizing the amount present in foods to minimize the amount needed while maximizing its food additive role.
Through this research, sodium nitrite has been found to give taste and color to the meat and inhibit lipid oxidation that leads to rancidity, with varying degrees of effectiveness for controlling growth of disease-causing microorganisms.

The ability of sodium nitrite to address the above-mentioned issues has led to production of meat with extended storage life and has improved desirable color and taste.
According to scientists working for the meat industry, nitrite has improved food safety.
This view is disputed in the light of the possible carcinogenic effects caused by adding nitrites to meat.

Nitrite has the E number E250.
Potassium nitrite (E249) is used in the same way.
Sodium nitrite is approved for usage in the EU, USA, and Australia and New Zealand.

In meat-processing, sodium nitrite is never used in a pure state but always mixed with common salt.
This mixture is known as nitrited salt, curing salt or nitrited curing salt.
In Europe, nitrited curing salt contains between 99.1% and 99.5% common salt and between 0.5% and 0.9% nitrite.

In the US, nitrited curing salt is dosed at 6% and must be remixed with salt before use.
Sodium nitrite is used as a medication together with sodium thiosulfate to treat cyanide poisoning.
Sodium nitrite is recommended only in severe cases of cyanide poisoning.

In those who have both cyanide poisoning and carbon monoxide poisoning sodium thiosulfate by itself is usually recommended.
Sodium nitrite is given by slow injection into a vein.

Side effects can include low blood pressure, headache, shortness of breath, loss of consciousness, and vomiting.
Greater care should be taken in people with underlying heart disease.
The patient's levels of methemoglobin should be regularly checked during treatment.

While not well studied during pregnancy, there is some evidence of potential harm to the baby.
Sodium nitrite is believed to work by creating methemoglobin that then binds with cyanide and thus removes it from the mitochondria.

Sodium nitrite came into medical use in the 1920s and 1930s
Sodium nitrite is on the World Health Organization's List of Essential Medicines.
Sodium nitrite is used in many industrial applications viz. in meat curing, coloring and preserving.

Sodium nitrite is used as a reagent in analytical chemistry, an antidote in cyanide poisoning, an electrolyte in electrochemical grinding, as a cooling solution in closed loop systems and as an additive in industrial greases.
Sodium nitrite finds application as a corrosion inhibitor as well as in the rubber industry.
In metallurgy, it is used for phosphatizing and detinning.

Sodium nitrite acts as a precursor to diazo dyes, nitroso compounds and various organic compounds like pharmaceuticals.
As a food additive, it is used to prevent botulism.
Sodium nitrite is used in many industrial processes, in meat curing, coloring, and preserving, and as a reagent in analytical chemistry.

Sodium nitrite is used therapeutically as an antidote in cyanide poisoning.
The compound is toxic and mutagenic and will react in vivo with secondary or tertiary amines thereby producing highly carcinogenic nitrosamines.

Toxicity:
Due to the oxidizing property of sodium nitrite, ingestion of the substance can induce methemoglobinemia as quickly as one hour after ingestion.
Methemoglobinemia occurs when the iron contained within hemoglobin is oxidized from its ferrous state (HgbFe2+) to its ferric state (HgbFe3+).
When hemoglobin is in its ferric state, it is called methemoglobin and it is unable to act as a carrier to deliver oxygen to tissues.

Symptoms of methemoglobinemia can include cyanosis and low SpO2 in the absence of respiratory distress, dizziness, syncope, dyspnea, fatigue, CNS depression, seizures, dysrhythmias, metabolic acidosis, cardiovascular collapse and death.
Generally symptoms start to occur with methemoglobin levels > 15%.
Sodium nitrite has a reported elimination half-life between 30-45 minutes when ingested or injected so does not tend to cause prolonged methemoglobinemia like that which is seen with dapsone.

Nitrite in blood is highly reactive with hemoglobin and causes methemoglobinemia.
The oxygen-carrying capacity of methemoglobin is much less than that of hemoglobin.
Human is more sensitive than rat in this respect.

So, the primary acute toxic effects of sodium nitrite in animals results from methemoglobinemia.
The secondary toxic effects of acute sodium nitrite in animals result in vasodilatation, relaxation of smooth muscle, and lowering of blood pressure.

Health Hazard:
Ingestion (or inhalation of excessive amounts of dust) causes rapid drop in blood pressure, persistent and throbbing headache, vertigo, palpitations, and visual disturbances; skin becomes flushed and sweaty, later cold and cyanotic; other symptoms include nausea, vomiting, diarrhea (sometimes), fainting, methemoglobinemia.
Contact with eyes causes irritation.

Dangerous fire and explosion risk when heated to 537C (1000F) or in contact with reducing materials; a strong oxidizing agent.
Carcinogen in test animals; its use in curing fish and meat products is restricted to 100 ppm.

Safety Profile:
Human poison by ingestion.
Experimental poison by ingestion, inhalation, subcutaneous, intravenous, and intraperitoneal routes.
Human systemic effects by ingestion: motor activity changes, coma, decreased blood pressure with possible pulse rate increase without fall in blood pressure, arteriolar or venous dlation, nausea or vomiting, and blood me themoglo binemiacarboxyhemoglobinemia.

Experimental teratogenic and reproductive effects.
Questionable carcinogen with experimental neoplas tigenic and tumorigenic data.
Human mutation data reported.

It may react with organic amines in the body to form carcinogenic nitrosamines.
Flammable; a strong oxidizing agent.
In contact with organic matter, will ignite by friction.

May explode when heated to over 100O0F or on contact with cyanides, NH4' salts, cellulose, LI, (K + NH3), Na2S203.
Incompatible with aminoguanidine salts, butadene, phthalic acid, phthalic anhydride, reductants, sodlum amide, sodmm disulfite, sodium thocyanate, urea wood.
When heated to decomposition it emits toxic fumes of NOx and NaaO. See also NITRITES.

Environmental Fate:
Sodium nitrite is a strong oxidizing agent at high temperature and also is a strong supporter of combustion.
It is freely soluble in water (very soluble in water (80%) at 20 °C), and slightly soluble in ethanol (0.3%) and methanol (0.45%).
Partition coefficient in octanol–water and log Pow is equal to -3.7.

Vapor pressure is 9.9E-17 hPa (7.44E-17mmHg).
Sodium nitrite may explode on heating above 530 °C, is not combustible but enhances combustion of other substances, and gives irritating or toxic fumes (or gases) in a fire.
Furthermore, based on the estimated Henry’s law constant at 25 °C ＝2.06E-07 atm-m3 mol-1 for sodium nitrite, volatilization from water and moist soil surface is not plausible.

Sodium nitrite dissociates immediately into sodium and nitrite ions in water.
Concentrations of nitrate in rainwater of up to 5mg l-1 have been observed in industrial areas.
In the air, the vapor phase of norethisterone can be degraded by reaction with photochemically produced hydroxyl radicals with an estimated half-life of 1.1 h, while the particulate phase can be removed by wet or dry deposition.

Norethisterone is likely susceptible to photolysis by sunlight because of posing chromophores that absorb at wavelengths more than 290 nm.
Hydrolysis of norethisterone is not anticipated under environmental condition because it lacks a functional group to hydrolyze.
Indirect photo oxidation by hydroxy radicals (1500 000 molecules cm-3) is predicted to occur with a half-life estimated at 82.3 days.

Synonyms:
SODIUM NITRITE
7632-00-0
Nitrous acid, sodium salt
sodium;nitrite
Nitrite, sodium
Natrium nitrit
Nitrito sodico
Nitrite de sodium
Natrum nitrosum
Nitrous acid soda
NaNO2
Sodium nitrite [USP]
MFCD00011118
CHEMBL93268
INS NO.250
M0KG633D4F
DTXSID0020941
CHEBI:78870
INS-250
NSC-77391
Sodium Nitrite-18O2 (10% 16O2)
Sodium nitrite (USP)
DTXCID00941
Caswell No. 782
Dusitan sodny [Czech]
Azotyn sodowy [Polish]
Azotyn sodowy
Natrium nitrit [German]
Nitrito sodico [Spanish]
Nitrite de sodium [French]
CCRIS 559
CAS-7632-00-0
HSDB 757
EINECS 231-555-9
NSC 77391
UN1500
EPA Pesticide Chemical Code 076204
UNII-M0KG633D4F
natrium nitrite
sodium nitrit
Natrii nitris
Sodium nitrite (TN)
Sodium nitrite ACS grade
EC 231-555-9
SODIUM NITRITE [MI]
SODIUM NITRITE [FCC]
SODIUM NITRITE [HSDB]
SODIUM NITRITE [INCI]
NATRUM NITROSUM [HPUS]
SODIUM NITRITE [VANDF]
SODIUM NITRITE [MART.]
Sodium nitrite, AR, >=98%
Sodium nitrite, LR, >=98%
SODIUM NITRITE [USP-RS]
SODIUM NITRITE [WHO-DD]
SODIUM NITRITE [WHO-IP]
LPXPTNMVRIOKMN-UHFFFAOYSA-M
HMS3652K08
Nitrous acid, sodium salt (1:1)
Sodium nitrite, analytical standard
Sodium nitrite, granular, 99.5%
Sodium nitrite, Trace metals grade
Tox21_202155
Tox21_300025
s4074
SODIUM NITRITE [ORANGE BOOK]
NATRII NITRIS [WHO-IP LATIN]
SODIUM NITRITE [EP MONOGRAPH]
AKOS024427981
SODIUM NITRITE [USP MONOGRAPH]
CCG-266007
NCGC00090737-01
NCGC00090737-02
NCGC00254137-01
NCGC00259704-01
Sodium nitrite [UN1500] [Oxidizer]
BP-31053
E250
NITHIODOTE COMPONENT SODIUM NITRITE
Sodium nitrite, ACS reagent, >=97.0%
Sodium nitrite, p.a., ACS reagent, 99%
FT-0645124
S0565
SODIUM NITRITE COMPONENT OF NITHIODOTE
Sodium nitrite, 99.5%, super free-flowing
Sodium nitrite, ReagentPlus(R), >=99.0%
SW219150-1
Sodium nitrite, 99.999% trace metals basis
Sodium nitrite, SAJ first grade, >=97.0%
D05865
E78844
Sodium nitrite, >=99.99% trace metals basis
Sodium nitrite, JIS special grade, >=98.5%
Sodium nitrite, purum p.a., >=98.0% (RT)
Q339975
Sodium nitrite, puriss. p.a., ACS reagent, >=99.0% (RT)
Sodium nitrite, United States Pharmacopeia (USP) Reference Standard
Sodium nitrite, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=97%
Sodium nitrite, puriss. p.a., ACS reagent, reag. Ph. Eur., >=99%

When pure, Sodium Nitrite is a white to slight yellowish crystalline powder.
Sodium Nitrite is very soluble in water and is hygroscopic.
Sodium Nitrite is also slowly oxidized by oxygen in the air to sodium nitrate, NaNO3.


CAS Number: 7632-00-0
EC Number: 231-555-9
MDL number: MFCD00011118
Chemical formula: NaNO2
Molecular Formula: NO2.Na / NaNO2 / NNaO2


Sodium nitrite is effective at delaying the development of lipid peroxidation, which is the major cause of oxidative rancidity.
Sodium Nitrite acts as an antioxidant and reacts with heme proteins and metal ions to neutralize free radicals produced by nitric oxide.
Neutralizing these free radicals terminates the cycle of lipid oxidation and thereby extends the shelf life of cured meats while maintaining visual appeal and taste.


Research has shown sodium nitrite to be an effective vasodilator that could be used to treat many conditions, such as stroke, heart attack, sickle cell anemia, respiratory diseases, and fungal, bacterial, and viral infections.
Sodium Nitrite has also been shown to be useful in reducing the risk of hospital-acquired nocosomial infections that result from the insertion of medical devices such as catheters.


Sodium Nitrite is a strong reducing agent.
Sodium nitrite can be synthesized through several different chemical reactions that involve the reduction of sodium nitrite.
However, the industrial production of sodium nitrite is mainly achieved through the absorption of nitrogen oxides into an aqueous solution of sodium carbonate or sodium hydroxide.


Sodium Nitrite is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.
Sodium Nitrite, chemical formula NaNO2, is a pale straw-colored material that is highly soluble in water.
The global sodium nitrite market size was valued at USD 418.1 million in 2022 and is anticipated to expand at a compound annual growth rate (CAGR) of 4.2% from 2023 to 2030.


The demand for Sodium Nitrite is anticipated to be driven by its increasing usage in meat-curing applications.
Additionally, the growth is also fueled by the growing demand for processed meat products, including sausages, seafood, bacon, and ham.
Sodium nitrite is a component in heat transfer salts used by many branches of industry such as the chemical, petrochemical and metalworking industries.


Sodium Nitrite is easily soluble in water, resulting in weak alkaline solutions.
The preparation of solutions is accompanied by a decrease in temperature.
Sodium nitrite is soluble in aqueous ammonia and various organic solvents (such as ethanediol, propanediol and methanol).


Sodium nitrite can act as an oxidizing and reducing agent.
Iron-steel, Al and many other metals do not decompose with sodium nitrite and its solutions.
The presence of chlorides and sulfates can promote corrosion of metals.
Rubber, plastics, glass, porcelain and ceramics are resistant to sodium nitrite solutions.


Treatment of sodium nitrite solutions with acids can result in the formation of nitric acid, which rapidly decomposes into nitro gases with a pale to dark brown color.
In deisotization and nitrosation processes, nitric acid can react with other reactants before decomposing into nitrous oxide phases.
It reacts with sodium nitrite, ammonium salts, amides and mixtures containing them at room temperature.


Sodium nitrite is a yellowish-white, odorless powder.
You may notice that a small amount of Sodium Nitrite is in certain foods.
Sodium nitrite appears as a yellowish white crystalline solid. Sodium Nitrite is noncombustible but will accelerate the burning of combustible material.


If large quantities of Sodium Nitrite are involved in a fire or if the combustible material is finely divided, an explosion may result.
If contaminated by ammonium compounds, spontaneous decomposition can occur and the resulting heat may ignite surrounding combustible material.
Sodium nitrite is an inorganic sodium salt having nitrite as the counterion.


Sodium Nitrite is a nitrite salt and an inorganic sodium salt.
Sodium nitrite is a chemical compound of sodium and nitrite ions.
Sodium Nitrite's chemical formula is NaNO2.


Sodium Nitrite is a white, slightly yellowish fine crystalline, hygroscopic chemical with high water solubility.
Sodium nitrite is an inorganic compound with the chemical formula NaNO2.
Sodium Nitrite is a white to slightly yellowish crystalline powder that is very soluble in water and is hygroscopic.


From an industrial perspective, Sodium Nitrite is the most important nitrite salt.
Sodium Nitrite is a precursor to a variety of organic compounds, such as pharmaceuticals, dyes, and pesticides, but it is probably best known as a food additive used in processed meats and (in some countries) in fish products.


In the early 1900s, irregular curing was commonplace.
This led to further research surrounding the use of sodium nitrite as an additive in food, standardizing the amount present in foods to minimize the amount needed while maximizing its food additive role.


Through this research, sodium nitrite has been found to give taste and color to the meat and inhibit lipid oxidation that leads to rancidity, with varying degrees of effectiveness for controlling growth of disease-causing microorganisms.
The ability of sodium nitrite to address the above-mentioned issues has led to production of meat with extended storage life and has improved desirable color and taste.
According to scientists working for the meat industry, nitrite has improved food safety.



USES and APPLICATIONS of SODIUM NITRITE:
Sodium Nitrite is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Sodium Nitrite is used in the following products: anti-freeze products, adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, finger paints, metal surface treatment products, non-metal-surface treatment products, inks and toners and lubricants and greases.


Other release to the environment of Sodium Nitrite is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Release to the environment of Sodium Nitrite can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Other release to the environment of Sodium Nitrite is likely to occur from: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Sodium Nitrite can be found in complex articles, with no release intended: vehicles, Vehicles (e.g. personal vehicles, delivery vans, boats, trains, metro or planes)), machinery, mechanical appliances and electrical/electronic products e.g. refrigerators, washing machines, vacuum cleaners, computers, telephones, drills, saws, smoke detectors, thermostats, radiators, large-scale stationary industrial tools) and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).


Sodium Nitrite can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), metal used for large surface area articles (e.g. construction and building materials used for roof sheets, pipes), metal used for packaging (excluding food packaging), metal used for furniture & furnishings (e.g. outdoor furniture, benches, tables), wood used for large surface area articles (e.g. construction and building materials for floors, claddings), wood used for furniture & furnishings and wood.


Sodium Nitrite is intended to be released from: packaging material for metal parts (releasing grease/corrosion inhibitors).
Sodium Nitrite is used in the following products: anti-freeze products, metal surface treatment products, adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, finger paints, non-metal-surface treatment products and inks and toners.


Sodium Nitrite is used in the following areas: formulation of mixtures and/or re-packaging, offshore mining and building & construction work.
Sodium Nitrite is used for the manufacture of: machinery and vehicles, chemicals, fabricated metal products and .
Release to the environment of Sodium Nitrite can occur from industrial use: formulation of mixtures and of substances in closed systems with minimal release.


Other release to the environment of Sodium Nitrite is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Sodium Nitrite is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, finger paints, metal surface treatment products, non-metal-surface treatment products and inks and toners.
Release to the environment of Sodium Nitrite can occur from industrial use: formulation of mixtures.


Sodium Nitrite is used in the following products: hydraulic fluids, lubricants and greases, heat transfer fluids, metal working fluids and anti-freeze products.
Sodium Nitrite is used in the following areas: offshore mining.
Sodium Nitrite is used for the manufacture of: chemicals, fabricated metal products and machinery and vehicles.


Release to the environment of Sodium Nitrite can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and in the production of articles.
Release to the environment of Sodium Nitrite can occur from industrial use: manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).


Sodium Nitrite is used in the following products: adhesives and sealants, coating products, fillers, putties, plasters, modelling clay, finger paints, metal surface treatment products, non-metal-surface treatment products and inks and toners.
Release to the environment of Sodium Nitrite can occur from industrial use: formulation of mixtures.


Sodium Nitrite is used in the following products: hydraulic fluids, lubricants and greases, heat transfer fluids, metal working fluids and anti-freeze products.
Sodium Nitrite is used in the following areas: offshore mining.
Sodium Nitrite is used for the manufacture of: chemicals, fabricated metal products and machinery and vehicles.


Release to the environment of Sodium Nitrite can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and in the production of articles.
Release to the environment of Sodium Nitrite can occur from industrial use: manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).


Sodium nitrite, with chemical formula NaNO2, and molar mass of 69.00 g/mol is used as a color fixative and preservative in meats and fish.
Sodium Nitrite is also used in manufacturing diazo dyes, nitroso compounds, and other organic compounds; in dyeing and printing textile fabrics and bleaching fibers; in photography; as a laboratory reagent and a corrosion inhibitor; in metal coatings for phosphatizing and detinning; and in the manufacture of rubber chemicals.


Sodium nitrite also has been used in human and veterinary medicine as a vasodilator, a bronchodilator, an intestinal relaxant or a laxative, and an antidote for cyanide poisoning.
Sodium Nitrite is used as a Food additive.


Sodium Nitrite is used as a food additive, it serves a dual purpose in the food industry since it both alters the color of preserved fish and meats and also prevents growth of Clostridium botulinum, the bacteria which causes botulism.
In the European Union Sodium Nitrite may be used only as a mixture with salt containing at most 0.6% sodium nitrite.


Sodium Nitrite has the E number E250. Potassium nitrite (E249) is used in the same way.
Sodium Nitrite is used in many products and industrial processes, including heat transfer salts, metal treatment and finishing, meat and fish preservatives, pharmaceuticals, and as an antidote to cyanide poisoning.


Sodium Nitrite is used in many industrial applications including the manufacturing of diazo dyes, and other organic compounds used in the manufacture of organic pigments for the paint, dye and printing ink industries.
In metal processing, Sodium Nitrite is used in phosphatizing and detinning applications.


As a molten salt bath, Sodium Nitrite is used in heat treating of metal parts in the automotive and aircraft industries and as a high temperature heat-transfer medium.
Sodium Nitrite is also used in the manufacture of synthetic rubbers and rubber chemicals.
Due to its anti-corrosion properties, Sodium Nitrite solution is also used as a heat transfer fluid in Thermal Energy Storage units for large air-conditioning or process cooling applications.


Sodium nitrite is used in many industrial applications viz. in meat curing, coloring and preserving.
Sodium Nitrite is used as a reagent in analytical chemistry, an antidote in cyanide poisoning, an electrolyte in electrochemical grinding, as a cooling solution in closed loop systems and as an additive in industrial greases.


Sodium Nitrite finds application as a corrosion inhibitor and in the rubber industry.
In metallurgy, Sodium Nitrite is used for phosphatizing and detinning.
Sodium Nitrite acts as a precursor to diazo dyes, nitroso compounds and various organic compounds like pharmaceuticals.


As a food additive, Sodium Nitrite is used to prevent botulism.
Sodium nitrite is a salt and an antioxidant that is used to cure meats like ham, bacon and hot dogs.
Nitrite salts are a key ingredient in many industrial processes, and sodium nitrite is the most important of them.
Sodium Nitrite is a precursor to several organic compounds used in pesticides, dyes, and pharmaceuticals.


Sodium Nitrite is best known for its use as an additive in processed meats and fish, but it is also a major compound used in metallurgy and pharmaceuticals.
Sodium nitrite is used as a heat transfer medium and for phosphatizing and detinning in the production of steel and aluminum alloys.
Sodium Nitrite is an anodic inhibitor that effectively interferes with the metal dissolution process.


As the sodium nitrite reacts with dissolved oxygen, Sodium Nitrite forms a protective gamma iron oxide film on metal surfaces and reduces the rate of corrosion.
When mixed with nitrite salts, sodium nitrite can be used to create a molten salt bath that is stable at high temperatures, has a low melting point and high heat transfer rate, and is non-corrosive to steel.


These molten salt baths are used for indirect heating and cooling or as a quenching bath in the process of annealing iron and steel.
As a result, sodium nitrite offers excellent protection for ferrous metals, such as those used in closed-loop water systems.
Since sodium nitrite functions best at a pH range of 9.0-10.5, it is often formulated with borate buffers in closed-loop systems.


When combined with sodium nitrite, borates help to facilitate the absorption of oxygen and provide microbiological control.
Sodium nitrite is commonly used as an aqueous solution in closed-loop heating and cooling systems.
Thanks to its corrosion-inhibiting properties, Sodium Nitrite is also used as an additive in industrial greases used in medium-speed, moderate-temperature applications on chassis, gears, wheel bearings, ball bearings, conveyors, machine parts, and other moving parts.


Sodium nitrite is used many other industrial processes, such as an acid neutralizer after chromium tanning in leather manufacturing and as a raw material for baking powder as a food additive.
Sodium Nitrite is used in synthesizing, processing, and purifying chemicals and polymers and serves as a catalyst, neutralizing, and buffering agent.


Sodium nitrite is a safe and effective chemical used for the biological control of wastewater treatment.
Sodium Nitrite helps maintain proper pH levels in wastewater, control sulfide odors, and reduces the demand for biological oxygen.
Sodium Nitrite is also proven to be one of the most effective collectors of sulfur dioxide.


Due to its odor-absorbing properties, and Sodium Nitrite is used in deodorizers for carpets, refrigerators, and garbage containers.
Sodium Nitrite is even used in the agricultural industry as a buffer to maintain the pH levels of rumens and alleviate butterfat depressions due to diets low in fiber and to aid in fiber digestibility.


In the poultry industry, sodium nitrite is used to maintain electrolyte balance, improve tolerance to heat stress, and improve eggshell quality.
Sodium Nitrite is used in tank rinsers used for the production of azo dyes, the production of diazo compounds, the production of nitroso and isonitrozo compounds, the stabilization of nitric acid gases, the delivery and storage of butadiene.


Sodium Nitrite is used as an accelerator during phosphating; in the preparation of baths for hot-worked metals; steel deposition and cast iron; as an additive to alkaline pickling baths of aluminum and aluminum alloys.
Sodium Nitrite is used in neutral cleaner and deactivating baths.


In water recovery systems, cooling water and cooling liquids (antifreezes); in crushing oils, hydraulic fluids, lubricants, extinguishers; in chemical processes; in the production of solid and liquid anti-corrosion agents; in the production of emulsion paints; antioxidant for special soaps; additive for glazing of glass raw materials; in water circulation systems; as an additive in concrete with special properties; as an anti-corrosion agent for steel and iron.


Sodium Nitrite is used in the production of products used to protect oil fuel tanks from corrosion.
Sodium Nitrite is used as a preservative in foods.
Sodium Nitrite inhibits bacterial growth and discoloration, generally


Sodium Nitrite finds its application in several industries including pharmaceuticals, textiles, and food & beverages.
Sodium Nitrite is employed as a preservative, mainly in the meat processing sector, because it serves as a color fixative and acts as an antioxidant and antimicrobial, preventing the growth of toxic bacterial microbes that spoil the food.


Sodium Nitrite is not only used in meat but in other perishable foods to prevent decay and maintain taste & freshness.
Sodium Nitrite is used as a food preservative, and to make other chemicals.
Sodium Nitrite is used as a food preservative and antidote to cyanide poisoning.


Sodium Nitrite has a role as an antimicrobial food preservative, an antihypertensive agent, a food antioxidant, a poison and an antidote to cyanide poisoning.
Sodium Nitrite is used mainly as a color fixative and preservative in meats and fish.
Sodium nitrite may also be used in organic synthesis, in dyeing and printing textile fabrics, in photography, as a laboratory reagent and a corrosion inhibitor, and in the manufacture of rubber chemicals.


Sodium nitrite also has been used in human and veterinary medicine as a vasodilator, a bronchodilator, and an antidote for cyanide poisoning.
Nitrite is a toxic compound known to cause methemoglobinemia.
Listed in the World Health Organization’s List of Essential Medicines, sodium nitrite is an effective drug for cyanide poisoning.


Sodium Nitrite is used as a humane toxin for wild boar control.
Sodium Nitrite is responsible for the desirable red colour in meat.
Sodium Nitrite is used as a food additive.


Sodium Nitrite is sodium salt of nitric acid, it is used as a preservative additive in foods.
In addition, studies have shown that sodium nitrite in the human body carries out the formation of new vessels and studies on this subject are continuing.
Sodium nitrite is an effective corrosion inhibitor and is used as an additive in industrial greases, as an aqueous solution in closed loop cooling systems, and in a molten state as a heat transfer medium.
Sodium Nitrite is used in a variety of metallurgical applications, for phosphatizing and detinning.


-Major Industrial Applications of Sodium Nitrite:
A major use of sodium nitrite is in the industrial production of organonitrogen compounds commonly used in pesticides.
Sodium Nitrite is also used as a reagent in the conversion of amines into diazo compounds and other organic compounds that are used in the production of dyes, pigments, and printing ink.
Sodium nitrite is also used in the synthesis of nitrites used to produce nitroso compounds that are used in the rubber and plastic industries as a blowing agent.


-Sodium nitrite is used as a medication together with sodium thiosulfate to treat cyanide poisoning.
Sodium Nitrite is recommended only in severe cases of cyanide poisoning.
In those who have both cyanide poisoning and carbon monoxide poisoning sodium thiosulfate by itself is usually recommended.
Sodium Nitrite is given by slow injection into a vein.


-In meat-processing, sodium nitrite is never used in a pure state but always mixed with common salt.
This mixture is known as nitrited salt, curing salt or nitrited curing salt.
In Europe, nitrited curing salt contains between 99.1% and 99.5% common salt and between 0.5% and 0.9% nitrite.
In the US, nitrited curing salt is dosed at 6% and must be remixed with salt before use.


-Medicine:
Sodium Nitrite is used as an antidote to treat cyanide poisoning.

-Food:
In the food sector, Sodium Nitrite with the E 250 number is used as a preservative.
Sodium Nitrite also combines with the myoglobin in the meat to produce and maintain the bright pink-red color of the processed meat.

-Health:
Sodium Nitrite is used to prevent the growth of clostridium botulinum bacteria, which is very dangerous for human health.


-For textile dyeing and printing:
Dyeing and printing diazotization; oxidation of printing and dyeing with colorless barrel dyes; protection against reduction during printing and dyeing with certain vat dyes.
Sodium Nitrite is used to trigger accelerated oxidation of barrel paints that resist reoxidation.


-Chemistry:
Sodium Nitrite is used in laboratories to remove excess sodium products.


-Food additive and preservative:
Sodium nitrite is used to speed up the curing of meat, inhibit the germination of clostridium botulinum spores, and also impart an attractive pink color.
Nitrite reacts with the meat myoglobin to cause color changes, first converting to nitrosomyoglobin (bright red), then, on heating, to nitrosohemochrome (a pink pigment).
Historically, salt has been used for the preservation of meat.
The salt-preserved meat product was usually brownish-gray in color.
When sodium nitrite is added with the salt, the meat develops a red, then pink color, which is associated with cured meats such as ham, bacon, hot dogs, and bologna.


-Industrial chemistry:
The main use of sodium nitrite is for the industrial production of organonitrogen compounds.
Sodium Nitrite is a reagent for conversion of amines into diazo compounds, which are key precursors to many dyes, such as diazo dyes.
Nitroso compounds are produced from nitrites.
hese are used in the rubber industry.


-Pharmaceutical Applications of Sodium Nitrite:
The use of sodium nitrite in the pharmaceutical industry started in the 1920s and 1930s, and it is listed on the World Health Organization’s List of Essential Medications.
Sodium Nitrite's most common use in the pharmaceutical industry is in the treatment of cyanide poisoning.
Sodium Nitrite is mixed with sodium thiosulfate and used as an injection.
Sodium nitrite has also proven to be an effective treatment for hydrogen sulfide poisoning.
Sodium Nitrite is also used as a raw ingredient in the synthesis of saccharines and caffeine.



WHAT IS SODIUM NITRITE USED FOR?
You’ll see sodium nitrite in some cured meats to help them last longer.
You might also notice Sodium Nitrite used for:
*A preservative in fish
*Animal control purposes
*Car maintenance
*Metal treatment and finishing
*Treatment in some cases of cyanide poisoning
*Certain medications



THE CHEMISTRY OF SODIUM NITRITE:
Sodium nitrite is an inorganic salt with the chemical formula NaNO2.
Sodium Nitrite can be in the form of a yellowish-white crystalline granule, powder, or rod.
Sodium Nitrite is odorless and noncombustible but can assist in the burning of other combustible materials.
As an ionic compound, Sodium Nitrite can be used as a strong reducing agent.
When dissolved in an acid solution, Sodium Nitrite becomes a strong oxidizer.



THE FOOD ADDITIVE SODIUM NITRITE MAY BE SAFELY USED IN OR ON SPECIFIED FOODS IN ACCORDANCE WITH THE FOLLOWING PRESCRIBED CONDITIONS:
(a) Sodium Nitrite is used or intended for use as follows:
(1) Sodium Nitrite is used as a color fixative in smoked cured tunafish products so that the level of sodium nitrite does not exceed 10 parts per million (0.001 percent) in the finished product.

(2) Sodium Nitrite is used as a preservative and color fixative, with or without sodium nitrate, in smoked, cured sablefish, smoked, cured salmon, and smoked, cured shad so that the level of sodium nitrite does not exceed 200 parts per million and the level of sodium nitrate does not exceed 500 parts per million in the finished product.

(3) Sodium Nitrite is used as a preservative and color fixative, with sodium nitrate, in meat-curing preparations for the home curing of meat and meat products (including poultry and wild game), with directions for use which limit the amount of sodium nitrite to not more than 200 parts per million in the finished meat product, and the amount of sodium nitrate to not more than 500 parts per million in the finished meat product.



HOW SODIUM NITRITE IS USED IN MEAT CURING AND PRESERVING?
The most common use of sodium nitrite in the food industry is as an additive that speeds up the curing process of meats and fish.
When sodium nitrite is added to meat, it reacts with myoglobin and causes color changes.
At first, the myoglobin is converted to nitrosomyoglobin, which results in a bright red color.
Then when heated, the nitrosomyoglobin is converted to nitrosohemochrome, resulting in a pink color.
When used for curing, sodium nitrite is always mixed with salt in what is commonly referred to as pink salt.
This mixture typically only contains 0.5% to 0.9% sodium nitrite.



PRODUCTION AND REACTIONS OF SODIUM NITRITE:
Sodium hydroxide can be obtained by treatment with nitrogen dioxide and nitric oxide.
2 NaOH + NO2 + NO? 2 NaNO2 + H2O
Sodium nitrite can be reduced to enter the reaction to destroy excess sodium products.
2 NaN 3 + 2 NaNO 2 + 2 H +? 3 N2 + 2 NO + 2 Na + 2 H2O
Sodium nitrite can be converted to nitric acid by reacting with gastric acid.



CHEMICAL REACTIONS OF SODIUM NITRITE:
In the laboratory, sodium nitrite can be used to destroy excess sodium azide.
2NaN3+2NaNO2+4H+⟶3N2+2NO+4Na+ +2H2O
Above 330 °C sodium nitrite decomposes (in air) to sodium oxide, nitric oxide and nitrogen dioxide.
2NaNO2⟶Na2O+NO+NO2
Sodium nitrite can also be used in the production of nitrous acid:
2NaNO2+H2SO4⟶2HNO2+Na2SO4
The nitrous acid then, under normal conditions, decomposes:
2HNO2⟶NO2+NO+H2O
The resulting nitrogen dioxide hydrolyzes to a mixture of nitric and nitrous acids:
2NO2+H2O⟶HNO3+HNO2



PRODUCTION OF SODIUM NITRITE:
Industrial production of sodium nitrite follows one of two processes, the reduction of nitrate salts, or the oxidation of lower nitrogen oxides.
One method uses molten Sodium Nitrite as the salt, and lead which is oxidized, while a more modern method uses scrap iron filings to reduce the nitrate.
A more commonly used method involves the general reaction of nitrogen oxides in alkaline aqueous solution, with the addition of a catalyst.
The exact conditions depend on which nitrogen oxides are used, and what the oxidant is, as the conditions need to be carefully controlled to avoid over oxidation of the nitrogen atom.
Sodium nitrite has also been produced by reduction of nitrate salts by exposure to heat, light, ionizing radiation, metals, hydrogen, and electrolytic reduction.



COLOR AND TASTE:
The appearance and taste of meat is an important component of consumer acceptance.
Sodium nitrite is responsible for the desirable red color (or shaded pink) of meat.
Very little nitrite is needed to induce this change.
Sodium Nitrite has been reported that as little as 2 to 14 parts per million (ppm) is needed to induce this desirable color change.
However, to extend the lifespan of this color change, significantly higher levels are needed.
The mechanism responsible for this color change is the formation of nitrosylating agents by nitrite, which has the ability to transfer nitric oxide that subsequently reacts with myoglobin to produce the cured meat color.
The unique taste associated with cured meat is also affected by the addition of sodium nitrite.
However, the mechanism underlying this change in taste is still not fully understood.



INHIBITION OF MICROBIAL PATHOGENES:
In conjunction with salt and pH levels, sodium nitrite reduces the ability of clostridium botulinum spores to grow to the point of producing toxin.
Some dry-cured meat products are manufactured without nitrites.
For example, Parma ham, which has been produced without nitrite since 1993, was reported in 2018 to have caused no cases of botulism.
Sodium nitrite has shown varying degrees of effectiveness for controlling growth of other spoilage or disease causing microorganisms.
Although the inhibitory mechanisms are not well known, its effectiveness depends on several factors including residual nitrite level, pH, salt concentration, reductants present and iron content.
The type of bacteria also affects sodium nitrite's effectiveness.
It is generally agreed that sodium nitrite is not effective for controlling Gram-negative enteric pathogens such as Salmonella and Escherichia coli.
Other food additives (such as lactate and sorbate) provide similar protection against bacteria, but do not provide the desired pink color.



INHIBITION OF LIPID PEROXIDATION:
Sodium nitrite is also able to effectively delay the development of oxidative rancidity.
Lipid peroxidation is considered to be a major reason for the deterioration of quality of meat products (rancidity and unappetizing flavors).
Sodium nitrite acts as an antioxidant in a mechanism similar to the one responsible for the coloring effect.
Nitrite reacts with heme proteins and metal ions, neutralizing free radicals by nitric oxide (one of its byproducts).
Neutralization of these free radicals terminates the cycle of lipid oxidation that leads to rancidity.



SODIUM NITRITE SERVES A VITAL PUBLIC HEALTH FUNCTION:
Sodium Nitrite blocks the growth of botulism-causing bacteria and prevents spoilage.
Nitrite also gives cured meats their characteristic color and flavor.
In addition,United States Department of Agriculture (USDA) sponsored research indicates that nitrite can help prevent the growth of Listeria monocytogenes, an environmental bacterium that can cause illness in some at-risk populations.



PHYSICAL and CHEMICAL PROPERTIES of SODIUM NITRITE:
Chemical formula: NaNO2
Molar mass: 68.9953 g/mol
Appearance: white or slightly yellowish solid
Density: 2.168 g/cm3
Melting point: 271 °C (520 °F; 544 K) (decomposes at 320 °C)
Solubility in water: 71.4 g/100 mL (0 °C), 84.8 g/100 mL (25 °C), 160 g/100 mL (100 °C)
Solubility: soluble in methanol (4.4 g/100 mL) ethanol
slightly soluble in diethyl ether (0.3 g/100 mL)
very soluble in ammonia
Acidity (pKa): ~9
Magnetic susceptibility (χ): −14.5·10−6 cm3/mol
Refractive index (nD): 1.65
Crystal structure: orthorhombic
Space group: Im2m
Lattice constant: a = 3.5653(8) Å, b = 5.5728(7) Å, c = 5.3846(13) Å
Formula units (Z): 2

Std molar entropy (S⦵298): 106 J/mol K
Std enthalpy of formation (ΔfH⦵298): −359 kJ/mol[2]
Gibbs free energy (ΔfG⦵): −295 kJ/mol

Molecular Weight: 68.995 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 68.98267252 g/mol
Monoisotopic Mass: 68.98267252 g/mol
Topological Polar Surface Area: 52.5Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 13.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes


Physical state: solid, Crystalline powder
Color: white, light yellow
Odor: odorless
Melting point/freezing point:
Melting point/range: 271 °C - lit.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 820 g/l at 20 °C
Partition coefficient: n-octanol/water:
Not applicable for inorganic substances
Vapor pressure: No data available
Density: 2,168 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Other safety information: No data available

CAS number: 7632-00-0
PubChem: 24269
ChemSpider: 22689
UNII: M0KG633D4F
EC Number: 231-555-9
UN number: 1500
CHEMBL93268
RTECS number: RA1225000
ATC code: V03AB08
Molecular formula: NaNO2
Molar mass: 68,9953 g / mol
Appearance: white or slightly yellowish solid
Density: 2.168 g / cm3
Melting point: 271 ° C, 544 K, 520 ° F (dec.)
Solubility in water: 84.8 g / 100 ml (25 ° C)
Solubility: (4.4 g / 100 mL) soluble in methanol ethanol
Very low soluble in diethyl ether (0.3 g / 100 mL) Very soluble in ammonia
Acidity (pKa): ~ 9
Refractive index (nD): 1.65
Structure: Crystal structure
R-phrases: R8, R25, R50
S-phrases: (S1 / 2), S45, S61
Auto-ignition temperature: 489 ° C

CAS number: 7632-00-0
EC index number: 007-010-00-4
EC number: 231-555-9
Grade: ACS,Reag. Ph Eur
Hill Formula: NNaO₂
Chemical formula: NaNO₂
Molar Mass: 69.00 g/mol
HS Code: 2834 10 00
Density: 2.168 g/cm3 (20 °C)
Melting Point: 280 °C (decomposition)
pH value: 9 (100 g/l, H₂O, 20 °C)
Bulk density: 1200 kg/m3
Solubility: 820 g/l
Name: Sodium Nitrite
Appearance: White crystalline solid
Chemical Formula: NaNO2
Melting Point: 271 °C
Boiling Point: Decomposes above 320 °C
Density: 2.17 g/cm³
Molar Mass: 68.9953 g/mol
Solubility in Water: Soluble
CAS: 7632-00-0
Molecular Formula: NNaO2
Molecular Weight (g/mol): 69.00
MDL Number: MFCD00011118
InChI Key: LPXPTNMVRIOKMN-UHFFFAOYSA-M

Melting Point: 271°C
Color: White
Physical Form: Crystals
Quantity: 100 g
Assay Percent Range: 99.999% (metals basis)
Solubility Information: Soluble in water,methanol,ethanol,ammonia,nitric acid.
Slightly soluble diethyl ether.
Formula Weight: 69
Odor: Odorless
Sensitivity: Hygroscopic
Density: 2.17
Chemical Name or Material: Sodium nitrite
Compound Formula: NNaO2
Molecular Weight: 69
Appearance: Slightly yellowish or white crystals
Melting Point: 271 °C
Boiling Point: N/A
Density: 2.17 g/cm3
Solubility in H2O: N/A
Exact Mass: 68.982673
Monoisotopic Mass: 68.982673



FIRST AID MEASURES of SODIUM NITRITE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM NITRITE:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SODIUM NITRITE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM NITRITE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SODIUM NITRITE:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep locked up or in an area accessible only to qualified or authorized persons.
hygroscopic



STABILITY and REACTIVITY of SODIUM NITRITE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
no information available
-Incompatible materials:
No data available



SYNONYMS:
SODIUM NITRITE
7632-00-0
Nitrous acid, sodium salt
sodium;nitrite
Nitrite, sodium
Natrium nitrit
Nitrito sodico
Nitrite de sodium
Natrum nitrosum
Nitrous acid soda
NaNO2
Sodium nitrite [USP]
MFCD00011118
CHEMBL93268
INS NO.250
M0KG633D4F
DTXSID0020941
CHEBI:78870
INS-250
NSC-77391
Sodium Nitrite-18O2 (10% 16O2)
Sodium nitrite (USP)
DTXCID00941
Caswell No. 782
Dusitan sodny [Czech]
Azotyn sodowy [Polish]
Azotyn sodowy
Natrium nitrit [German]
Nitrito sodico [Spanish]
Nitrite de sodium [French]
CCRIS 559
CAS-7632-00-0
HSDB 757
EINECS 231-555-9
NSC 77391
UN1500
EPA Pesticide Chemical Code 076204
UNII-M0KG633D4F
natrium nitrite
sodium nitrit
Natrii nitris
Sodium nitrite (TN)
Sodium nitrite ACS grade
EC 231-555-9
SODIUM NITRITE [MI]
SODIUM NITRITE [FCC]
SODIUM NITRITE [HSDB]
SODIUM NITRITE [INCI]
NATRUM NITROSUM [HPUS]
SODIUM NITRITE [VANDF]
SODIUM NITRITE [MART.]
Sodium nitrite, AR, >=98%
Sodium nitrite, LR, >=98%
SODIUM NITRITE [USP-RS]
SODIUM NITRITE [WHO-DD]
SODIUM NITRITE [WHO-IP]
HMS3652K08
Nitrous acid, sodium salt (1:1)
Sodium nitrite, analytical standard
Sodium nitrite, granular, 99.5%
Sodium nitrite, Trace metals grade
Tox21_202155
Tox21_300025
s4074
SODIUM NITRITE [ORANGE BOOK]
SODIUM NITRITE [EP MONOGRAPH]
AKOS024427981
SODIUM NITRITE [USP MONOGRAPH]
CCG-266007
NCGC00090737-01
NCGC00090737-02
NCGC00254137-01
NCGC00259704-01
Sodium nitrite [UN1500]
BP-31053
E250
NITHIODOTE COMPONENT SODIUM NITRITE
Sodium nitrite, ACS reagent, >=97.0%
Sodium nitrite, p.a., ACS reagent, 99%
FT-0645124
S0565
SODIUM NITRITE COMPONENT OF NITHIODOTE
Sodium nitrite, 99.5%, super free-flowing
Sodium nitrite, ReagentPlus(R), >=99.0%
SW219150-1
Sodium nitrite, 99.999% trace metals basis
Sodium nitrite, SAJ first grade, >=97.0%
D05865
E78844
Sodium nitrite, >=99.99% trace metals basis
Sodium nitrite, JIS special grade, >=98.5%
Sodium nitrite, purum p.a., >=98.0% (RT)
Q339975
Sodium nitrite, puriss. p.a., ACS reagent, >=99.0% (RT)
Sodium nitrite, United States Pharmacopeia (USP) Reference Standard
Sodium nitrite, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=97%
Sodium nitrite, puriss. p.a., ACS reagent, reag. Ph. Eur., >=99%

DESCRIPTION:

Sodium N-lauroylsarcosinate is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Sodium N-lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium N-lauroylsarcosinate is a synthetic anionic surfactant that is widely used in various personal care and cosmetic products.



CAS NUMBER: 137-16-6

EC NUMBER: 205-281-5

MOLECULAR FORMULA: C15H28NNaO3

MOLECULAR WEIGHT: 293.38 g/mol




DESCRIPTION:

Sodium N-lauroylsarcosinate belongs to the family of sarcosinates and is derived from sarcosine, a natural amino acid.
pH-sensitive vesicles can be prepared using this surfactant with another cationic or water-insoluble amphiphiles such as 1-decanol.
Sodium N-lauroylsarcosinate is a compound of synthetic or vegetable origin.
As a surfactant, Sodium N-lauroylsarcosinate most often functions as a cleaning agent, which also acts as an emulsifier.
Due to its properties, Sodium N-lauroylsarcosinate is used in cleansing products for the face and body, as well as in shampoos.

Widely Sodium N-lauroylsarcosinate is used in various industries such as cosmetics, detergents, household and industrial cleaning.
Sodium N-lauroylsarcosinate is the name of an anionic surfactant from the group of surfactants.
The chemical name of this substance is N-lauroylsarcosine sodium salt.
Alternative names for this compound are sodium N-lauroylsarcosinate and Sarcosyl NL.
Sodium N-lauroylsarcosinate exists both as a solid and in the form of an aqueous solution with an active substance concentration of about 30%.

Sodium N-lauroylsarcosinate is usually used as a secondary surfactant in a concentration range of 1-5%.
Sodium N-lauroylsarcosinate is a safe amino acid-based surfactant that works well with a variety of glycols, silicones, solvents, and phosphate esters, making it very versatile in cosmetic formulations.
Sodium N-lauroylsarcosinate offers excellent chemical stability and is known for a skin-friendly pH that does not cause additional irritation.

Sodium N-lauroylsarcosinate is a versatile surfactant commonly used in various personal care and cosmetic products due to its excellent cleansing and foaming properties.
Sodium N-lauroylsarcosinate's mildness compared to other surfactants like sodium lauryl sulfate (SLS) makes it suitable for a wide range of applications.
Sodium N-lauroylsarcosinate is a cleansing agent that enhances the lather effect which helps in the effectiveness of many cosmetic products.
Sodium N-lauroylsarcosinate is often chosen as one of the substrates of cosmetic formulations due to its ease of use and its effectiveness.

Sodium N-lauroylsarcosinate can be used together with SLS-containing and SLS-free preparations.
Sodium N-lauroylsarcosinate has mild degreasing properties that help restore softness and hydration to the skin.
Sodium N-lauroylsarcosinate is especially useful in haircare products, where it adds volume and helps to smooth the surface of the hair follicles.
Thanks to these properties, the effect of well-nourished and smooth hair is obtained.
Sodium N-lauroylsarcosinate has some antistatic properties (prevents static electricity in the hair), which further increase its usefulness in haircare products.

In addition, Sodium N-lauroylsarcosinate plays a preservative role in care products and reduces the highly irritating effect of other substances.
Sodium N-lauroylsarcosinate is an effective surfactant, meaning it has both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts.
This allows it to lower the surface tension between liquids and facilitate the mixing of oil and water.
Sodium N-lauroylsarcosinate is commonly used in products like shampoos, body washes, and facial cleansers to produce a rich and stable lather, enhancing the cleansing experience.
Sodium N-lauroylsarcosinate is often used in products targeted at individuals with sensitive skin.

Sodium N-lauroylsarcosinate is generally considered more environmentally friendly and biodegradable compared to some other surfactants.
Sodium N-lauroylsarcosinate is used as an ingredient in shampoos, face cleansers for children and adults, bath lotions and toothpastes.
In addition, Sodium N-lauroylsarcosinate can be found in intimate hygiene liquids or make-up removal products.
Sodium N-lauroylsarcosinate is also used in household detergents and their professional counterparts for industrial applications, for cleaning surfaces, in particular for cleaning vehicles.

Sodium N-lauroylsarcosinate is a highly active substance and at the same time it is very gentle to the skin.
Sodium N-lauroylsarcosinate is an ionic detergent used to purify membrane proteins.
Sodium N-lauroylsarcosinate is a surfactant that is used in water treatment, wastewater treatment, and as a detergent.
Sodium N-lauroylsarcosinate is also used as an analytical tool for the titration calorimetry of sodium salts.
Sodium N-lauroylsarcosinate is a sodium salt that belongs to the group of sodium salts. It has been shown to have biological properties such as permeability through
human serum and biodegradability.
The salt form of Sodium N-lauroylsarcosinate has an electrochemical impedance spectrum which can be used to identify it.
Sodium N-lauroylsarcosinate is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
Sodium N-lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium N-lauroylsarcosinate is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes.

Sodium N-lauroylsarcosinate can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
The typical usage levels range from 1-5% on an active basis.
Sodium N-lauroylsarcosinate is a cleansing agent that is widely used in products like shampoos, toothpastes and other wash products.

Sodium N-lauroylsarcosinate produces a generous amount of foam that makes the application and feel of the products much better.
In its raw form, SSodium N-lauroylsarcosinate can be either powder or liquid that is mild in nature.
Sodium N-lauroylsarcosinate is basically the salt of lauryl sarcosinate.
The chemical formula of Sodium N-lauroylsarcosinate is C15H28NNaO3.



USAGE:

Sodium N-lauroylsarcosinate helps to clean the hair and scalp effectively while producing a creamy lather.
Sodium N-lauroylsarcosinate is used for its cleansing and foaming properties in face washes and cleansing creams.
Sodium N-lauroylsarcosinate helps in providing a smooth and comfortable shave.
Sodium N-lauroylsarcosinate is used for handwashing and body cleansing.

Sodium N-lauroylsarcosinate is commonly found in hair care products as it effectively cleanses the hair and scalp while producing a rich and stable lather.
Sodium N-lauroylsarcosinate is used in both regular shampoos and sulfate-free or milder formulations.
Sodium N-lauroylsarcosinate is a key ingredient in body washes and shower gels, providing effective cleansing and a luxurious foaming experience.
This surfactant is often included in shaving products to aid in providing a smooth surface for shaving, reducing friction, and enhancing the overall shaving experience.

Sodium N-lauroylsarcosinate is used in toothpaste formulations to help disperse ingredients and create a smooth texture.
Sodium N-lauroylsarcosinate also contributes to the foaming action during brushing.
Sodium N-lauroylsarcosinate is commonly used in liquid hand soaps for handwashing and body cleansing, offering a balance of cleansing and mildness.
Sodium N-lauroylsarcosinate can be found in pre-moistened cleansing wipes, which are convenient for quick and on-the-go cleansing.
Due to its mildness, Sodium N-lauroylsarcosinate is used in baby shampoos, body washes, and bath products.

Sodium N-lauroylsarcosinate may also be found in intimate washes and feminine hygiene products.
Sodium N-lauroylsarcosinate can be present in cleansing lotions or creams used for removing impurities and makeup while maintaining a gentle touch.
Because of its mild and non-irritating nature, Sodium N-lauroylsarcosinate is often used in products specially formulated for sensitive skin.



APPLICATIONS:

Sodium N-lauroylsarcosinate is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products. The surfactant is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium N-lauroylsarcosinate is a high foam, eco-friendly surfactant.
Sodium N-lauroylsarcosinate has good chlorine stability with anti-corrosion properties.
Sodium N-lauroylsarcosinate has excellent ocular tolerance and gentleness.

Sodium N-lauroylsarcosinate is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sodium N-lauroylsarcosinate has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.
This ingredient also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Sodium N-lauroylsarcosinate is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.



PHYSICAL AND CHEMICAL PROPERTIES:

-water-soluble,
-pH value in the range of 7.5 – 8.5,
-solid form: colourless substance,
-aqueous solution: colourless to light yellow liquid,
-molecular weight: 293.38 u.



ADVANTAGES:

-as a primary and secondary surfactant, it is gentle on the skin,
-excellent washing properties,
-very good foaming properties, also in a higher pH range,
-Sodium N-lauroylsarcosinate is biodegradable,
-Sodium N-lauroylsarcosinate is obtained from natural plant materials,
-Sodium N-lauroylsarcosinate is responsible for the long-lasting comfort and softness of the skin,
-suitable for use in children’s skincare preparations,
-Sodium N-lauroylsarcosinate is hypoallergenic and non-comedogenic,
-Sodium N-lauroylsarcosinate has an antistatic and conditioning effect on the hair.



FUNCTION:

-Antistatic
-Cleansing
-Emulsifying
-Foaming
-Surfactant



SPECIFICATIONS:

-Molecular Weight: 293.38 g/mol
-Hydrogen Bond Donor Count: 0
-Hydrogen Bond Acceptor Count: 3
-Rotatable Bond Count: 12
-Exact Mass: 293.19668804 g/mol
-Monoisotopic Mass: 293.19668804 g/mol
-Topological Polar Surface Area: 60.4Ų
-Heavy Atom Count: 20
-Complexity: 260
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 2
-Compound Is Canonicalized: Yes



CHARACTERISTICS:

-PSA： 60.4
-XLogP3： 2.11560
-Appearance： White Powder
-Density： 1.033 g/mL at 20 °C
-Melting Point： 46 °C
-Boiling Point： 100ºC
-Flash Point： 267℃
-Water Solubility： soluble in water (293 g/L).
-Storage Conditions： room temp
-Vapor Pressure： 0.02 hPa (20 °C)



PROPERTIES:

-Molecular Formula: C₁₅H₂₈NNaO₃
-Appearance: White to Off-White Solid
-Melting Point: 147-150°C
-Molecular Weight: 293.38
-Chemical Formula
-Smiles: CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+]
-Melting Point: 146 °C
-Density: 1.14 g/cm3
-Vapour Pressure: 0.02 hPa




SPECIFICATIONS:

-Appearance: White to Almost white powder to crystal
-Purity(with Total Nitrogen): min. 98.0 %(calcd.on anh.substance)
-Water max.: 7.0 %
-Suitability for protein-analysis: to pass test




PHYSICAL AND CHEMICAL PROPERTIES:

-Density: 1.14 g/cm3 (20 °C)
-Flash point: 267 °C
-Melting Point: 146 °C
-pH value: 8 (30 g/l, H₂O, 20 °C)
-Vapor pressure: 0.02 hPa (20 °C)
-Bulk density: 400 kg/m3



STORAGE:

Should be stored at 4°C.



SYNONYM:

137-16-6
Sodium lauroylsarcosinate
Sodium N-lauroylsarcosinate
N-Lauroylsarcosine sodium salt
Sarkosyl NL
Sodium lauroyl sarcosinate
Gardol
Sarkosyl
Medialan LL-99
Sarcosyl NL
Maprosyl 30
Compound 105
Hamposyl L-30
Sarcosyl NL 30
Sarkosyl NL 30
Sarkosyl NL 35
Sarkosyl NL 97
Sarkosyl NL 100
Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt
Sodium lauroylsarcosine
Caswell No. 778B
Sodium N-lauroylsarcosine
N-Lauroylsarcosine, sodium
Lauroylsarcosine sodium salt
MFCD00042728
N-Lauroylsarcosine, sodium salt
sodium lauroyl sarcosine
EINECS 205-281-5
EPA Pesticide Chemical Code 000174
NSC 117874
N-Dodecanoyl-N-methylglycine, sodium salt
n-lauryl sarcosine sodium salt
Lauroylsarcosine (sodium)
DTXSID0027066
UNII-632GS99618
Sarcosine, N-lauroyl-, sodium salt
sodium 2-(N-methyldodecanamido)acetate
sodium [dodecanoyl(methyl)amino]acetate
632GS99618
EC 205-281-5
N-Methyl-N-(1-oxododecyl)glycine, sodium salt
Sodium N-Dodecanoylsarcosinate
N-Methyl-N-(1-oxododecyl)glycine sodium salt (1:1)
Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1)
N-Dodecanoylsarcosine Sodium Salt
Lauroylsarcosine (sodium salt)
NSC-117874
SODIUM N-LAUROYL SARCOSINATE
Sodium N-dodecanoyl-N-methylglycinate
N-Dodecanoyl-N-methylglycine sodium salt
starbld0009501
GARDOL [MI]
MEDIALAN LL-33
N-Lauroylsarcosine-S-salt
Sodium N- lauroylsarcosinate
SCHEMBL23451
C15H29NO3.Na
Lauroylsarcosine, Sodium Salt
DTXCID907066
CHEMBL1903482
C15-H29-N-O3.Na
KSAVQLQVUXSOCR-UHFFFAOYSA-M
SODIUM LAUROYL SARCOSINE 1KG
Tox21_202996
AKOS015901704
SODIUM LAUROYL SARCOSINATE [II]
NCGC00164323-01
NCGC00260541-01
SODIUM LAUROYL SARCOSINATE [INCI]
AS-81025
CAS-137-16-6
SODIUM LAUROYL SARCOSINATE [VANDF]
sodium;2-[dodecanoyl(methyl)amino]acetate
HY-125920
LS-178955
SODIUM LAUROYL SARCOSINATE [USP-RS]
CS-0103267
FT-0631797
L0019
S0597




IUPAC NAME:

2-[dodecanoyl(methyl)amino]acetic acid; sodium
N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL, Sodium lauroyl sarcosinate
N-Lauroylsarcosine, sodium salt
N-Methyl-N-(1-Oxododecyl)Glycine, Sodium Salt
ORAMIX L 30
sodium 2-(N-methyldodecanamido)acetate
sodium 2-[dodecanoyl(methyl)amino]acetate
sodium [dodecanoyl(methyl)amino]acetate
SODIUM LAUROYL SARCOSINATE
SODIUM LAUROYL SARCOSINATE
Sodium lauroyl sarcosinate
Sodium Lauryl Sarconinate
Sodium N-Lauroylsarcosinate
Sodium N-lauroylsarcosinate
sodium N-lauroylsarcosinate
Sodium N-lauroylsarcosinate/Sodium lauroylsarcosinate
Sodium-N-Lauroylsarcosinate

Sodium N-Lauroylsarcosinate, also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
Sodium N-Lauroylsarcosinate is a white powder.
Sodium N-Lauroylsarcosinate is totally eco-friendly.


CAS Number: 137-16-6
EC Number: 205-281-5
MDL Number:MFCD00042728
Chemical formula: C15H28NNaO3



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GARDOL, GARDOL [MI], MEDIALAN LL-33, MEDIALAN LL-99, N-LAUROYLSARCOSINE SODIUM SALT, N-METHYL-N-(1-OXODODECYL)GLYCINE SODIUM SALT (1:1), NSC-117874, SARKOSYL, SODIUM LAUROYL SARCOSINATE [II], SODIUM LAUROYL SARCOSINATE [INCI], SODIUM LAUROYL SARCOSINATE [USP-RS], SODIUM LAUROYL SARCOSINATE [VANDF], SODIUM N-LAUROYL SARCOSINATE, SODIUM N-LAUROYLSARCOSINATE, Sodium N-(Dodecanoyl)-N-methylglycinate, Sodium (N-methyldodecanamido)acetate, SARKOSYL, SARCOSYL, N-Methylglycinol, N-LAUROYLSARCOSINE SODIUM SALT, GARDOL, SODIUM LAUROYL SARCOSINE, LAUROYLSARCOSINE, SODIUM SALT, N-methyl-N-(1-oxodecyl)glycine sodium salt, auroyL, GardolR, 137-16-6, Sodium lauroylsarcosinate, N-Lauroylsarcosine sodium salt, Sodium N-lauroylsarcosinate, Sarkosyl NL, Sodium lauroyl sarcosinate, Gardol, Sarkosyl, Medialan LL-99, Lauroylsarcosine sodium salt, Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt, Sarcosyl NL, Sarcosyl, Maprosyl 30, Compound 105, Hamposyl L-30, Sarcosyl NL 30, Sarkosyl NL 30, Sarkosyl NL 35, Sarkosyl NL 97, Sarkosyl NL 100, Sodium lauroylsarcosine, MFCD00042728, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosine, Sarcosinate LN 3, Firet L, Hamposyl L 95, N-Lauroyl-N-methylglycine sodium salt, Soypon SLP, Nikkol Sarcosinate LN 3, Oramix L 30, GM 9011, N-Dodecanoylsarcosine sodium salt, Sarkosyl, Enagicol L 30N, Soypon SLE, Sarcosinate LN 30, Medialan LD, Protelan LS 9011, Crodasinic LS 95, Perlastan L 30, Nikkol Sarcosine Na, SKL, SKL (salt), Crodasinic LS 30, Neoscoap SLN 100, Nikkol Sarcosinate LN 30, Crodasinic LS 30NP, Maprosyl 30B, FS 701, Nikkol Sarcosinates LN, Surfacare L 30, LS 30 (surfactant), PUJI AS02-30, AS 02-30, Amin LS 30NP, Ucefactant LS 30N, Crodasinic LS 40, LS 30, Aminosyl L 30, 1322-85-6, 75195-12-9, 76724-33-9, 912455-41-5, N-Dodecanoylsarcosine Sodium Salt, GARDOL, Sodium N-Lauroylsarcosinate, Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt, N-Lauroyl sarcosine sodium salt, Maprosyl 30, Sodium N-Dodecanoylsarcosinate, SARKOSYL, Sarcosyl,Sarkosyl NL,Sodium N-dodecanoyl-N-methylglycinate, SARKOSYL NL-30, sodium N-lauroyl-sarcosinate, SARCOSYL, GardolR, N-Dodecanoyl-N-methylglycine sodium salt,Sarkosyl NL, N-Lauroylsarcosine sodium salt, SARCOSYL NL, SARKOSYL NL, Sodium N-Lauroylsarcosinate, Compound 105, N-Methyl-N-(1-oxododecyl)glycine, sodium salt, Sodium lauroyl sarcosinate, Compound 105, Gardol, Hamposyl L-30, N-Lauroylsarcosine, sodium, N-Lauroylsarcosine, sodium salt, N-Dodecanoyl-N-methylglycine sodium salt, Lauroylsarcosine (sodium), DTXSID0027066, N-Dodecanoyl-N-methylglycine, sodium salt, sodium [dodecanoyl(methyl)amino]acetate, 632GS99618, Sarcosine, N-lauroyl-, sodium salt, Sodium N-Dodecanoylsarcosinate, Glycine, N-methyl-N-(1-oxododecyl)-, sodium salt (1:1), N-Dodecanoylsarcosine Sodium Salt, Lauroylsarcosine (sodium salt), NSC-117874, sodium lauroyl sarcosine, SODIUM N-LAUROYL SARCOSINATE, EINECS 205-281-5, EPA Pesticide Chemical Code 000174, NSC 117874, n-lauryl sarcosine sodium salt, UNII-632GS99618, sodium 2-(N-methyldodecanamido)acetate, starbld0009501, GARDOL [MI], MEDIALAN LL-33, EC 205-281-5, N-Methyl-N-(1-oxododecyl)glycine, sodium salt, SCHEMBL23451, Lauroylsarcosine, Sodium Salt, DTXCID907066, N-Methyl-N-(1-oxododecyl)glycine sodium salt (1:1), CHEMBL1903482, KSAVQLQVUXSOCR-UHFFFAOYSA-M, Tox21_202996, AKOS015901704, SODIUM LAUROYL SARCOSINATE [II], NCGC00164323-01, NCGC00260541-01, SODIUM LAUROYL SARCOSINATE [INCI], AS-81025, CAS-137-16-6, SODIUM LAUROYL SARCOSINATE [VANDF], sodium, 2-[dodecanoyl(methyl)amino]acetate, HY-125920, SODIUM LAUROYL SARCOSINATE [USP-RS], CS-0103267, FT-0631797, L0019, S0597, E81236, A934513, Q309660, W-108241, N-Lauroylsarcosine sodium, Sodium lauroyl sarcosinate, N-Dodecanoyl-N-methylglycinesodium salt, Glycine,N-methyl-N-(1-oxododecyl)-,sodium salt (1:1), Sarcosine,N-lauroyl-,sodium salt, Glycine,N-methyl-N-(1-oxododecyl)-,sodium salt, Compound 105, Gardol (antiseptic), N-Lauroylsarcosine sodium, Medialan LL 99, Sarkosyl NL, Sarkosyl NL 100, Sodium lauroylsarcosine, Sodium N-lauroylsarcosinate, Sarkosyl NL 97, Sarkosyl NL 30, Sodium N-lauroylsarcosine, Gardol, N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL 35, N-Lauroylsarcosine sodium salt, Sodium Lauroyl Sarcosinate, Maprosyl 30, Lauroylsarcosine sodium salt, Lauroyl sarcosine sodium, Secosyl, Hamposyl L 30, Nikkol Sarcosinate LN, Sarcosinate LN,



Sodium N-Lauroylsarcosinate is non-flammable.
Sodium N-Lauroylsarcosinate, also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
Sodium N-Lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.


Sodium N-Lauroylsarcosinate offers excellent chemical stability and is known for a skin-friendly pH that does not cause additional irritation.
Coconut is a common source of Sodium N-Lauroylsarcosinate in cosmetic products.
Sodium N-Lauroylsarcosinate is a highly active substance and at the same time it is very gentle to the skin.


Sodium N-Lauroylsarcosinate has not been classified as a potential allergen.
Safety evaluations confirmed that Sodium N-Lauroylsarcosinate is non-irritating and non-sensitizing when applied to human skin in amounts of up to 15% for rinse-off detergents and 5% for leave-on products.


Sodium N-Lauroylsarcosinate, also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
Sodium N-Lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Sodium N-Lauroylsarcosinate is a white powder.


Sodium N-Lauroylsarcosinate is an anionic surfactant with an ability to denature proteins.
Due to its microbicidal property, Sodium N-Lauroylsarcosinate is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).


Sodium N-Lauroylsarcosinate is a sodium salt of Lauroyl Sarcosinate, an ester of Lauroyl alcohol and Sarcosine amino acid.
Sodium N-Lauroylsarcosinate is a secondary surfactant in a wide range of cleansing applications.
Sodium N-Lauroylsarcosinate can work with mild surfactants like betaines or replace them as it is also an alkyl-amino acid type surfactant similarly gentle and effective.


Milder than Mono Alkyl Phosphates, Sodium N-Lauroylsarcosinate exhibits superior mildness and lower irritation potential.
In addition, Sodium N-Lauroylsarcosinate has an excellent sensory profile, leaving a long-lasting soft and silky after-feel on the skin.
Foaming properties are comparable with betaines and alkyl ether sulfates.


Sodium Lauroyl Sarcosinate, often known as Sarcosyl, is one of the most widely used amino acid-derived surfactants.
Amino acid surfactants are a group of surfactants derived from amino acids and fatty acids.
They have been trending surfactants to use in a wide range of personal care products for their complete biodegradability, high safeness, mildness, and non-irritation properties.


Sodium N-Lauroylsarcosinate is derived from sarcosine, a natural amino acid found in the human body and just about every type of biological material from animals to plants.
Sodium N-Lauroylsarcosinate is a safe amino acid-based surfactant that works well with a variety of glycols, silicones, solvents, and phosphate esters, making it very versatile in cosmetic formulations.


Sodium N-Lauroylsarcosinate is approved for use in cosmetics, even those intended for the care of children.
Sodium N-Lauroylsarcosinate, also known as sarkosyl, is a white powder derived from sarcosine, which make it is fate-free and biodegradable.
Sodium N-Lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.


In mineral flotation, Sodium N-Lauroylsarcosinate has a good synergistic effect with cationic surfactants and achieves higher flotation efficiency.
Sodium N-Lauroylsarcosinate is a new type of amino acid anionic surfactant.
Sodium N-Lauroylsarcosinate has the characteristics of washing, emulsifying, permeating and solubilizing.


Sodium N-Lauroylsarcosinate is an anionic surfactant from the group of amino-acid surfactants with INCI name: Sodium Lauroyl Sarcosinate.
Sodium N-Lauroylsarcosinate is produced basing on biomimetics, which are raw materials imitating naturally occurring chemical compounds and fatty acids (raw materials of plant origin).


Sodium N-Lauroylsarcosinate is totally eco-friendly.
Sodium N-Lauroylsarcosinate has good biodegradability and no pollution to the environment, at all.
Sodium N-Lauroylsarcosinate has the properties of antimicrobial, bactericidal, mildew-proof, corrosion-proof and antistatic.



USES and APPLICATIONS of SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is mild, effective, and a great foam maker in a wide range of pH, so it can be used for manufacturing various kinds of products.
Sodium N-Lauroylsarcosinate is used for manufacturing: Bathroom cleaners, Carpet and floor cleaners, Antistatic agents, Drain products, Bleaches and disinfectants, Hair products (shampoo, hair conditioners, hair bleach, etc.), Body hygiene products (body scrub, body wash, hand soap, body lotion, etc.).


Sodium N-Lauroylsarcosinate is used Personal care products (face wash, deodorant, face moisturizer/ cream/ mask, fragrance, etc.),
Children and babies’ products (shampoo, baby oil, baby powder, etc.),
Dental care (mouthwash and toothpaste), Make-up and related, Indirect food additive (FDA approved).


Sodium N-Lauroylsarcosinate is an ionic surfactant derived from sarcosine (an amino acid found naturally in the body).
Sodium N-Lauroylsarcosinate is used as a secondary surfactant and can be combined with other surfactants to boost foam and luxury.
Sodium N-Lauroylsarcosinate has mild refatting properties that helps to bring softeness and moisture to the skin.


When added to haircare products, Sodium N-Lauroylsarcosinate adds volume and helps smooth the hair follicle surface.
Sodium N-Lauroylsarcosinate has some anti-static properties which further enhances its usefulness in haircare products.
Sodium N-Lauroylsarcosinate can be used in formulation of shampoo, shower gel, face wash , bath foam.


Sodium N-Lauroylsarcosinate is provided as an aqueous solution with the active substance content of approx. 30%.
Sodium N-Lauroylsarcosinate is widely used in various industries (cosmetics, detergents, household and industrial cleaning, agro-chemicals, textiles processing).


Application of Sodium N-Lauroylsarcosinate: shampoos, especially very mild baby shampoos, body washing liquids, shower gels, bath lotion, bubble baths, gentle liquid soaps, materials for face cleaning and care, toothpastes, shaving foams, household and industrial cleaning product, and glass cleaning concentrates.


Biologically, Sodium N-Lauroylsarcosinate can be utilized for the isolation of RNA and DNA, as a solubilizer in cell purification, as an additive in the isolation of DNA from human serum, as well as to increase the nitrogen fixation capacity of leguminous Rhizobium by adding this product, and has many applications in immunochemistry.


Sodium N-Lauroylsarcosinate can be corrosion inhibitor and rust remover in metal processing.
In pharmacology and pharmacology, Sodium N-Lauroylsarcosinate can slow down the irritation of vitamin E to skin, increase the absorption of vitamins, and increase the antimicrobial and durability of eye ointment.


Sodium N-Lauroylsarcosinate can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.
The typical usage levels range from 1-5% on an active basis.
Sodium N-Lauroylsarcosinate is used as a detergent, foaming agent, and antienzyme for dentifrices.


Sodium N-Lauroylsarcosinate is permitted for use as an inert ingredient in non-food pesticide products.
Sodium N-Lauroylsarcosinate, also known as sarkosyl, is an ionic surfactant derived from sarcosine, used as a foaming and cleansing agent in shampoo, shaving foam and foam wash products.


In molecular biology experiments, Sodium N-Lauroylsarcosinate is used to inhibit the initiation of DNA transcription.
Sodium N-Lauroylsarcosinate is a mild ionic surfactant derived from sarcosine (amino acid) and fatty acids.
This reaction is catalyzed by alkali.


Sodium N-Lauroylsarcosinate is used for producing cleaning products and household care.
Sodium N-Lauroylsarcosinate has excellent foaming property and fine and durable foam.
Sodium N-Lauroylsarcosinate is suitable for foaming agent, shampoo and shaving cream for toothpaste and cosmetics.


Sodium N-Lauroylsarcosinate is widely applied in the industry as a detergent, foaming agent, and anti-enzyme.
Sodium N-Lauroylsarcosinate is applied in many cleaning products as a foaming and cleansing compound, such as shampoos, hair conditioners, children’s hygiene products, carpet cleaners, etc.


Sodium N-Lauroylsarcosinate is widely used in industry, especially for cleaning products and household care.
Addition of an mixture of equal parts of Sodium N-Lauroylsarcosinate and the non-ionic surfactant sorbitan monolaurate (S20) to a buffered water:ethanol solution led to the formation of micelle-like aggregates, even though neither surfactant formed micelles when present alone.


Such aggregates can help carry other small molecules, such as drugs, through the skin.
Sodium N-Lauroylsarcosinate is mild, biodegradable anionic surfactants derived from fatty acids and sarcosine (amino acid).
These compounds features lather building and resistance to sebum delathering in cleaners, polymers, industrial chemicals, petroleum and lubricant products.


Sodium N-Lauroylsarcosinate can reduce the irritation caused by the residue of traditional surfactants on the skin with it's good compatibility
properties.
As Sodium N-Lauroylsarcosinate has good biodegrability, it is in accordance with the requirement of environmental protection.


Sodium N-Lauroylsarcosinate is a cleanser and foaming agent that helps with the effectiveness and feel of our toothpaste.
Sodium N-Lauroylsarcosinate is widely used as a primary or secondary anionic surfactant in toothpaste, facial cleansers, ultra-gentle shampoos, and baby bath bubble lotions.


Sodium N-Lauroylsarcosinate has excellent foaming and cleaning ability in a wide pH range.
However, Sodium N-Lauroylsarcosinate has low degreasing power, which makes it not over-lift the needful oil on the skin, hence leaving the skin a moist and non-tight feeling.


Sodium N-Lauroylsarcosinate is a compound of synthetic or vegetable origin.
As a surfactant, Sodium N-Lauroylsarcosinate most often functions as a cleaning agent, which also acts as an emulsifier.
Sodium N-Lauroylsarcosinate is permitted in baby care cleansing applications such as head-to-toe shampoos.


In addition, Sodium N-Lauroylsarcosinate is a common ingredient in high-end hair shampoo, body and face washes, shower gels, facial cleansers, and toothpaste.
Sodium N-Lauroylsarcosinate, also known as sarcosyl, is an anionic surfactant derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.


Sodium N-Lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.
Since the nitrogen atom is in an amide linkage, the nitrogen is not pH active and is neutrally charged in all aqueous solutions regardless of pH.
The carboxylate has a pKa of about 3.6 and is therefore negatively charged in solutions of pH greater than about 5.5.


Sodium N-Lauroylsarcosinate is mild, biodegradable anionic surfactants derived from sarcosine used as a foaming and cleansing agent in shampoo, shaving foam, toothpaste, and foam wash products.
Sodium N-Lauroylsarcosinate is amphiphilic due to the hydrophobic 12-carbon chain (lauroyl) and the hydrophilic carboxylate.


Sodium N-Lauroylsarcosinate is a high foam, eco-friendly surfactant.
Sodium N-Lauroylsarcosinate has good chlorine stability with anti-corrosion properties.
Sodium N-Lauroylsarcosinate has excellent ocular tolerance and gentleness.


Sodium N-Lauroylsarcosinate is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sodium N-Lauroylsarcosinate has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.


Sodium N-Lauroylsarcosinate also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Sodium N-Lauroylsarcosinate is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.


Sodium N-Lauroylsarcosinate is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes.
Sodium N-Lauroylsarcosinate can also be used in oral care applications such as toothpastes and incorporated into syndet and combo bars.


The typical usage levels of Sodium N-Lauroylsarcosinate is range from 1-5% on an active basis.
Sodium N-Lauroylsarcosinate is used for solubilization and separation of membrane proteins and glycoprotein's; reported to inhibit hexokinase.
Sodium N-Lauroylsarcosinate is useful in concentrated salt solutions used in the cell lysis step during RNA purification (helps avoid excessive foaming).


Sodium N-Lauroylsarcosinate has been used to indicate paramagnetic anisotropy sign change in micelle mesophage.
Sodium N-Lauroylsarcosinate has some anti-static properties which further enchance its usefullness in haircare products.
Sodium N-Lauroylsarcosinate inhibits bacterial flora of human saliva/gut at 0.25% as well as acting as a fungi static agent in aqueous dispersion (1%).


Sodium N-Lauroylsarcosinate is used Detergent, foaming agent, antienzyme for dentifrices.
Sodium N-Lauroylsarcosinate is suitable for solubilization and separation of membrane proteins, lysis of cells during the isolation of RNA, and inhibition of hexokinase


pH-sensitive vesicles can be prepared using Sodium N-Lauroylsarcosinate with another cationic or water-insoluble amphiphiles such as 1-decanol.
Due to its properties, Sodium N-Lauroylsarcosinate is used in cleansing products for the face and body, as well as in shampoos.
Sodium N-Lauroylsarcosinate is widely used in various industries such as cosmetics, detergents, household and industrial cleaning.


Sodium N-Lauroylsarcosinate, also known as sarkosyl, is an ionic surfactant used as a cleansing agent in toothpaste, shampoo, and shaving foam.
Ungraded products supplied by BioWorld are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.


Sodium N-Lauroylsarcosinate is used as an ingredient in shampoos, face cleansers for children and adults, bath lotions and toothpastes.
In addition, Sodium N-Lauroylsarcosinate can be found in intimate hygiene liquids or make-up removal products.
Sodium N-Lauroylsarcosinate is used Paint, ink additives, increase compatibility and stability;


Sodium N-Lauroylsarcosinate is used in medicine as a solvent for cell purification.
Sodium N-Lauroylsarcosinate is an anionic surfactant, especially suitable for the preparation of shampoo, bath liquid, cleansing milk, baby detergent, tableware detergent and so on.


Sodium N-Lauroylsarcosinate is an ionic surfactant used as a foaming agent in foam wash products
Sodium N-Lauroylsarcosinate is derived from sarcosine (an amino acid found naturally in the body) and Normally used as a secondary surfactant to boost foam and luxury.


Sodium N-Lauroylsarcosinate helps in hair formulations to enhance suppleness of hair and improve body.
Adds mildness to final formulations whilst also boosting the foam of the formulation.
Sodium N-Lauroylsarcosinate can be used alongisde both SLS and SLS Free formulations to increase foam and luxuriousness.


Sodium N-Lauroylsarcosinate is especially useful in haircare products where it aids volume and helps smooth the hair folicle surface.
Sodium N-Lauroylsarcosinate is also used in household detergents and their professional counterparts for industrial applications, for cleaning surfaces, in particular for cleaning vehicles.


Sodium N-Lauroylsarcosinate is personal care products as well as in household and industrial applications, and it is used as a co-surfactant in cleanser formulations such as shampoos and body washes.
Sodium N-Lauroylsarcosinate is used in medicine as a solvent for cell purification.


Sodium N-Lauroylsarcosinate is used Corrosion inhibitor and rust remover in metal processing.
Sodium N-Lauroylsarcosinate has mild refatting properties that helps to bring softeness and moisture to the skin.
Besides, Sodium N-Lauroylsarcosinate is biodegradable.



PROPERTIES AND APPLICATIONS OF SODIUM N-LAUROYLSARCOSINATE:
Advantages of the product:
*anionic surfactant very gentle for skin,
*very good foaming properties,
*reduces the irritant effect of other surfactants on skin,
*excellent cleaning properties,
*provides the skin long-term comfort and softness sensation,
*due to high absorbtion on the surface of hair, reduction of static *electricity and binding, provides the hair soft and silky sensation,
*it is easily biodegradable,
*based on renewable raw materials of plant-origin,
*contains no preservatives,
*may be used in the presence of oxidizing agents.



FEATURES AND BENEFITS OF SODIUM N-LAUROYLSARCOSINATE:
*Mild, safe, and low irritation.
*Excellent stability and foamability in the pH range from strong base to weak acid.
*Low degreasing power, gives the skin a moist and non-tight feeling after washing.
*Good compatibility and can be compounded with other anionic surfactants to reduce irritation and improve foaming performance.



ADVANTAGES OF SODIUM N-LAUROYLSARCOSINATE:
The most important advantages of Sodium N-Lauroylsarcosinate:
*as a primary and secondary surfactant, it is gentle on the skin, excellent washing properties,
*very good foaming properties, also in a higher pH range,
*it is biodegradable,
*it is obtained from natural plant materials,
*is responsible for the long-lasting comfort and softness of the skin,
*suitable for use in children’s skincare preparations,
*it is hypoallergenic and non-comedogenic,
*it has an antistatic and conditioning effect on the hair.



GENERAL CHARACTERISTICS OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate (C15H28NO3) is the INCI name of an anionic surfactant from the group of surfactants.
The chemical name of Sodium N-Lauroylsarcosinate is N-lauroylsarcosine sodium salt.

Alternative names for Sodium N-Lauroylsarcosinate are sodium N-lauroylsarcosinate and Sarcosyl NL.
The CAS number that uniquely identifies Sodium N-Lauroylsarcosinate is 137-16-6.
Sodium N-Lauroylsarcosinate exists both as a solid and in the form of an aqueous solution with an active substance concentration of about 30%.
Sodium N-Lauroylsarcosinate is usually used as a secondary surfactant in a concentration range of 1-5%.



FUNCTIONS OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is often seen in shampoos, bath, cleansing and shaving products as a foaming agent, surfactant, and hair conditioning agent.
Sodium N-Lauroylsarcosinate has the ability to enhance the appearance and feel of hair by improving body, suppleness and sheen, especially in hair that is chemically damaged.

Sodium N-Lauroylsarcosinate also serves to clean skin and hair by mixing with oil and dirt and enabling them to be rinsed away.
As a modified fatty acid, Sodium N-Lauroylsarcosinate is thought to be more soluble, and have increased crystallinity and acidity compared to its original fatty acid composition.



CHEMICAL AND PHYSICAL PROPERTIES OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is an amphiphilic surfactant, due to its 12- carbon hydrophobic tail and the hydrophilic carboxylate head.
The chemical formula of Sodium N-Lauroylsarcosinate is C15H28NNaO3.
Since Sodium N-Lauroylsarcosinate has a nitrogen as amide bond and doesn’t exhibit pH activity, this molecule can be charged at any pH in aqueous solutions.



IN CULTURE, SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate was sold as a special ingredient called "Gardol" in Colgate "Dental Cream", as toothpaste was then called, during the 1950s through the mid-1960s in the US and the mid-1970s in France.
Its current use as a preventive dentifrice is in Arm & Hammer Baking Soda Toothpaste, a Church & Dwight product, where Sodium N-Lauroylsarcosinate is used as a surfactant.

Sodium N-Lauroylsarcosinate, like SDS is also used to denature proteins and disrupt biological membranes.
Sodium N-Lauroylsarcosinate is an sodium salt of an acyl derivative of sarcosine, which is a natural amino acid found in muscles and other body tissues.
Acyl sarcosines are considered modifiŽed fatty acids in which the hydrocarbon chains are interrupted by an amidomethyl group in the alpha position.

They are used as hair-conditioning agents and surfactant-cleansing agents in cosmetics, as well as to improve wetting and penetration of topical pharmaceutical products.
Acyl sarcosines and their sodium salts are also used in the metal finishing and processing industries for their crystal modifying, anti-rust, and anti-corrosion properties.



WHY WE USE SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is very mild, but also very effective.
What’s more, FDA approved as an indirect food additive, and CIR approved when used in rinse-off products, or in leave-on products at concentrations of 5% or less.



HOW TO USE SODIUM N-LAUROYLSARCOSINATE:
Normally used as a secondary surfactant at 1 -5% to increase the midlness and boost foam of foaming formulations.
To aid stability of the final formulation, the pH should be greater than 6.



SAFETY OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is a safe, non-toxic, and mild cleansing agent with excellent cleansing/foaming performance even in hard water, thanks to ideal compatibility with skin and hair.
Sodium N-Lauroylsarcosinate is also a readily biodegradable and environmentally friendly ingredient.



BIOCHEM/PHYSIOL ACTIONS OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is an anionic surfactant which also has protein denaturant potency.
In addition, Sodium N-Lauroylsarcosinate has been shown as a microbicide for sexually transmitted diseases.



THE ROLE AND ACTION OF SODIUM N-LAUROYLSARCOSINATE IN COSMETICS AND PERSONAL CARE PRODUCTS:
The role and action of Sodium N-Lauroylsarcosinate in cosmetics and personal care products:
Sodium N-Lauroylsarcosinate is a cleansing agent that enhances the lather effect which helps in the effectiveness of many cosmetic products.
Sodium N-Lauroylsarcosinate is often chosen as one of the substrates of cosmetic formulations due to its ease of use and its effectiveness.

Sodium N-Lauroylsarcosinate can be used together with SLS-containing and SLS-free preparations.
Sodium N-Lauroylsarcosinate has mild degreasing properties that help restore softness and hydration to the skin.
Sodium N-Lauroylsarcosinate is especially useful in haircare products, where it adds volume and helps to smooth the surface of the hair follicles.

Thanks to these properties, the effect of well-nourished and smooth hair is obtained.
Sodium N-Lauroylsarcosinate has some antistatic properties (prevents static electricity in the hair), which further increase its usefulness in haircare products.
In addition, Sodium N-Lauroylsarcosinate plays a preservative role in care products and reduces the highly irritating effect of other substances.



PHYSICAL AND CHEMICAL PROPERTIES OF SODIUM N-LAUROYLSARCOSINATE:
*water-soluble,
*pH value in the range of 7.5 – 8.5,
*solid form: colourless substance,
*aqueous solution: colourless to light yellow liquid,
*molecular weight: 293.38 u.



STABILITY/SHELF LIFE OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is stable at a wide pH range, except in strong acid and alkali.



CHEMICALS AND SURFACTANTS DETAILS OF SODIUM N-LAUROYLSARCOSINATE:
Sodium N-Lauroylsarcosinate is an anionic surfactant derived from sarcosine
Sodium N-Lauroylsarcosinate is used as a foaming and cleansing agent in shampoo, bodywash,handwash,facewash.



PHYSICAL and CHEMICAL PROPERTIES of SODIUM N-LAUROYLSARCOSINATE:
Appearance：White Powder
Density：1.033 g/mL at 20 °C
Melting Point：46 °C
Boiling Point：100ºC
Flash Point：267℃
Water Solubility：soluble in water (293 g/L).
Storage Conditions：room temp
Vapor Pressure：0.02 hPa (20 °C)
Stability: Stable.
Water Solubility: H2O: 1 M at 20 °C, clear, colorless
Appearance Form: powder
Colour: white
Odour: No data available
Odour Threshold: No data available
pH: 7,0 - 9 at 293 g/l at 25 °C

Melting point/freezing point: 146,1 °C at 1.013 hPa
Initial boiling point and boiling range: 350 - 410 °C at 1.013 hPa
Flash point: 267 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapour pressure: 0,02 hPa at 20 °C
Vapour density: No data available
Relative density: 1,141 g/cm3 at 20 °C
Water solubility: 293 g/l at 20 °C - completely soluble
Molecular Weight: 294.39
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 12
Exact Mass: 294.20451307
Monoisotopic Mass: 294.20451307
Topological Polar Surface Area: 57.6 Ų
Heavy Atom Count: 20
Formal Charge: 0

Complexity: 254
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Color: White
Melting Point: 44°C to 47°C
Linear Formula: CH3(CH2)10CON(CH3)CH2COONa
Beilstein: 5322974
Merck Index: 14,4368
Solubility Information: Soluble in water (293g/L).
Sensitivity: Hygroscopic
Formula Weight: 293.38
Physical Form: Crystalline Powder
Density: 1.033 g/mL at 20 °C

Boiling Point: 100ºC
Melting Point: 46 °C
Molecular Formula: C15H28NNaO3
Molecular Weight: 293.378
Exact Mass: 293.196686
PSA: 60.44000
LogP: 2.11560
Storage condition: room temp
Chemical formula: C15H28NNaO3
Molar mass: 293.383 g·mol−1
Melting point: 140 °C (284 °F; 413 K)
Physical state: powder
Color: white
Odor: characteristic
Melting point/freezing point
Melting point: 146 °C
Initial boiling point and boiling range: 350 - 410 °C at 1.013 hPa
Flammability (solid, gas): No data available

Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: ca.8 at 30 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: at 20 °C soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: 0,02 hPa at 20 °C
Density: 1,14 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available

Melting point: 46 °C
Density: 1.033 g/mL at 20 °C
vapor pressure: 0.02 hPa (20 °C)
RTECS: MC0598960
Flash point: 267℃
storage temp.: room temp
solubility: H2O: 1 M at 20 °C, clear, colorless
form: Powder
Specific Gravity: 1.03 (20/4℃)
color: White
Odor: at 100.00?%. bland
PH: 7.0-9.0 (25℃, 1M in H2O)
Water Solubility: Soluble in water (293 g/L).
Sensitive: Hygroscopic
λmax:
λ: 260 nm Amax: 0.2
λ: 280 nm Amax: 0.06
Merck: 14,4368

BRN: 5322974
Stability: Stable.
LogP: 0.37
CAS DataBase Reference 137-16-6(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances: SODIUM LAUROYL SARCOSINATE
FDA 21 CFR: 175.105; 177.1200
FDA UNII: 632GS99618
EPA Substance Registry System: Sodium N-lauroylsarcosinate (137-16-6)
Cosmetics Info: Sodium Lauroyl Sarcosinate
Molecular Weight: 293.38 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 12
Exact Mass: 293.19668804 g/mol
Monoisotopic Mass: 293.19668804 g/mol
Topological Polar Surface Area: 60.4Ų
Heavy Atom Count: 20
Formal Charge: 0

Complexity: 260
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Molecular Weight: 293.38
Exact Mass：293.196686
EC Number：205-281-5
UNII：632GS99618
DSSTox ID：DTXSID0027066
HScode：34021190
PSA： 60.4
XLogP3：2.11560



FIRST AID MEASURES of SODIUM N-LAUROYLSARCOSINATE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM N-LAUROYLSARCOSINATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SODIUM N-LAUROYLSARCOSINATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM N-LAUROYLSARCOSINATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SODIUM N-LAUROYLSARCOSINATE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
*Storage stability:
Recommended storage temperature
2 - 8 °C



STABILITY and REACTIVITY of SODIUM N-LAUROYLSARCOSINATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

SODIUM OCTYL SULFATE; N° CAS : 142-31-4; Nom INCI : SODIUM OCTYL SULFATE; Classification : Sulfate

cas no 143-19-1 cis-9-Octadecenoic acid sodium salt; Oleic acid sodium salt; 9-Octadecenoic acid (Z)-, sodium salt; sodium (9Z)-octadec-9-enoate;

DESCRIPTION:
Oleic acid, [sodium salt] is a light tan solid with a slight tallow-like odor.
Sinks and mixes slowly with water.
Sodium oleate is an organic molecular entity.

CAS: 143-19-1
European Community (EC) Number: 205-591-0
Molecular Formula: C18H33NaO2


Sodium oleate, also known as oleic acid sodium, is a monounsaturated fatty acid abundant in human adipocytes and other tissues.
Sodium oleate acts as an activator of Na+/K+ ATPase.
Oleic acid stimulates cell proliferation and migration in highly metastatic cancer cells by enhancing β-oxidation through AMPK activation.

Conversely, Sodium oleate inhibits cancer cell growth and survival in low metastatic carcinoma cells, including gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines.
Furthermore, sodium oleate activates PKC (Protein Kinase C) in hepatocytes.


Sodium Oleate is the sodium salt of oleic acid, a common unsaturated fatty acid found in many animals and plants such as olive oil.

Sodium Oleate is White powder; slight tallowlike odor.
Sodium Oleate is Soluble in water with partial decom- position; soluble in alcohol.
Sodium Oleate is Combustible.
Sodium Oleate is Light tan solid with a slight tallow-like odor.
Sodium Oleate Sinks and mixes slowly with water.
Oleic acid, [sodium salt] is a light tan solid with a slight tallow-like odor.


Oleic acid, [sodium salt] is a light tan solid with a slight tallow-like odor. Sinks and mixes slowly with water. (USCG, 1999)|Sodium oleate is an organic molecular entity.

APPLICATIONS OF SODIUM OLEATE:
Oleic acid is used to investigate effects on apolipoprotein B synthesis, degradation and secretion in cultured cells



CHEMICAL AND PHYSICAL PROPERTIES OF SODIUM OLEATE:
Molecular Weight
304.4 g/mol
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
15
Exact Mass
304.23782457 g/mol
Monoisotopic Mass
304.23782457 g/mol
Topological Polar Surface Area
40.1Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
239
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
1
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
2
Compound Is Canonicalized
Yes
Melting point 232-235 °C (lit.)
storage temp. -20°C
solubility Methanol (Slightly)
form Powder
color White to slightly yellow
Odor slt tallow odor
Water Solubility soluble H2O, partially decomposes; soluble alcohol [HAW93]
Merck 14,6828
BRN 4046357
Hydrophilic-Lipophilic Balance (HLB) 18
Color White
Flashpoint 149 °C
Form Solid
Grade Chemical Synthesis
Incompatible Materials Strong oxidizing agents
Melting Point/Range 232-235 °C
Purity Percentage 82.00
Purity Details ≥82.00%
Solubility in Water Slightly soluble
pH-Value 11 (20 °C)
Storage Temperature Ambient
PSA：
40.1
XLogP3：
4.77380
Appearance：
White to slightly yellow Powder
Density：
0.9 g/cm3
Melting Point：
232-235 °C
Boiling Point：
360°C at 760 mmHg
Flash Point：
270.099ºC
Water Solubility：
soluble H2O, partially decomposes; soluble alcohol
Storage Conditions：
−20°C
Toxicity：
LD50 ivn-mus: 152 mg/kg RPOBAR 2,327,70
Odor：
SLIGHT TALLOW-LIKE ODOR
PH：
IN AQ SOLN IT IS ALKALINE... BUT NOT IN ALCOHOL SOLN
Air and Water Reactions：
Water soluble. Gives basic aqueous solution.
Water Solubility 2.8e-05 g/L
logP 7.56
logP 6.78
logS -7
pKa (Strongest Acidic) 4.99
Physiological Charge -1
Hydrogen Acceptor Count 2
Hydrogen Donor Count 0
Polar Surface Area 40.13 Ų
Rotatable Bond Count 15
Refractivity 98.24 m³•mol⁻¹
Polarizability 36.6 ų
Number of Rings 0
Bioavailability No
Rule of Five No
Ghose Filter No
Veber's Rule No
MDDR-like Rule No







SAFETY INFORMATION ABOUT SODIUM OLEATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product







SYNONYMS OF SODIUM OLEATE:
osteum
sodium oleate
SODIUM OLEATE
143-19-1
Oleic acid sodium salt
Osteum
Eunatrol
Olate flakes
Oleic acid, sodium salt
Oleate, sodium
Sodium 9-octadecenoate, (Z)-
9-Octadecenoic acid (Z)-, sodium salt
Sodium 9-octadecenoate
CCRIS 1964
HSDB 758
oleate sodium
16558-02-4
EINECS 205-591-0
sodium (Z)-octadec-9-enoate
sodium;(Z)-octadec-9-enoate
UNII-399SL044HN
9-Octadecenoic acid (9Z)-, sodium salt
9-Octadecenoic acid, sodium salt, (Z)-
AI3-19806
9-Octadecenoic acid, sodium salt
399SL044HN
MFCD00004438
Sodiumoleate
DTXSID7021077
CHEBI:81860
E-470(II)OLEIC ACID, SODIUM SALT
INS-470(II)OLEIC ACID, SODIUM SALT
INS NO.470(II)OLEIC ACID, SODIUM SALT
SODIUM OLEATE (MART.)
SODIUM OLEATE [MART.]
sodium (9Z)-octadec-9-enoate
cis-9-Octadecenoic acid sodium salt
Oleic acidsodium salt
Sodium oleate, >=99%
SCHEMBL3582
C18H33NaO2
SODIUM OLEATE [HSDB]
SODIUM OLEATE [INCI]
DTXCID001077
SODIUM OLEATE [WHO-DD]
CHEMBL3527599
HY-N1446B
BCKXLBQYZLBQEK-KVVVOXFISA-M
OLEATE SODIUM [GREEN BOOK]
OLEIC ACID SODIUM SALT [MI]
Sodium oleate, >=98.5% (GC)
AKOS017345104
Sodium oleate, >=95% (capillary GC)
AS-10421
CS-0107318
O0057
C18601
9-Octadecenoic acid (9Z)-, sodium salt (1:1)
A885003
Q17397737
Oleic acid sodium;9-cis-Octadecenoic acid sodium;9Z-Octadecenoic acid sodium

Sodium Oleate is an abundant monounsaturated fatty acid sodium.
Sodium Oleate (C18H33O2Na, CAS Reg. No. 143–19–1) is the sodium salt of oleic acid (cis-9-octadecenoic acid).
Sodium Oleate exists as a white to yellowish powder with a slight tallow-like odor.


CAS Number: 143-19-1
EC Number: 205-591-0
MDL number: MFCD00004438
Linear Formula: CH3(CH2)7CH=CH(CH2)7COONa


Sodium Oleate is a Na+/K+ATPase activator.
Commercially, Sodium Oleate is made by mixing and heating flaked sodium hydroxide and oleic acid.
Sodium Oleate is one of the numerous organometallic compounds sold.


Organometallics are useful reagents, catalysts, and precursor materials with applications in thin film deposition, industrial chemistry, pharmaceuticals, LED manufacturing, and others.
Sodium Oleate (NaC18H33O2) is an organic additive which is the sodium “salt” of oleic acid.


Sodium Oleate comes as a powder of small, yellowish crystals that dissolve in water and alcohol.
Sodium Oleate is a sodium salt of oleic acid.
Sodium Oleate is a light tan solid with a slight tallow-like odor. Sodium Oleate sinks and mixes slowly with water.


Sodium Oleate is an organic molecular entity.
Sodium Oleate is classified under CAS No.143-19-1.
Sodium Oleate is also known as Oleic Acid Sodium Salt, Sodium Salt of Oleic Acid.


Sodium Oleate occurs as a white to yellowish powder or as light brown yellow coarse powder or lumps.
Sodium Oleate has characteristic odor & taste.
Sodium Oleate is soluble in alcohol and water.


Sodium Oleate is a major component of soap as emulsifying agent.
Sodium Oleate is white to yellowish powder and lumps.
Sodium Oleate is soluble in warm water, slightly soluble in 90% ethanol.


Sodium Oleate is slightly like butter.
Sodium Oleate is alkaline due to hydrolysis, but the alcohol solution is not hydrolyzed.
Sodium Oleate has good solubility in hot water, the aqueous solution is light yellow and transparent, alkaline, soluble in ethanol, and the solution is neutral; it is slowly oxidized in the air to darken the color


Sodium Oleate is the sodium salt of oleic acid.
Sodium Oleate functions as a binder, emulsifier, and anticaking agent.
Sodium oleate, also known as sodium oleic acid, belongs to the class of organic compounds known as long-chain fatty acids.


These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
Sodium oleate is a weakly acidic compound (based on its pKa).
Sodium Oleate is a mild cleansing and foaming agent generally used in soaps.


Sodium Oleate is derived from natural fats and oils.
Sodium Oleate is an organic molecular entity.
Sodium Oleate is light tan solid with a slight tallow-like odor.


Sodium Oleate sinks and mixes slowly with water.
Sodium Oleate is water soluble.
Sodium Oleate gives basic aqueous solution.


Sodium oleate is an unsaturated fatty acid that features a kink in the long-chain hydrocarbon tail of its molecules due to a cis double bond.
Though the biochemical is already being utilized for a variety of applications, scientists are currently investigating the fatty acid in hopes of coming to a better understanding of Sodium Oleate and finding additional uses for it.


As a fatty acid, Sodium Oleate is not generally found free in nature, but rather occurs as a component of more complex naturally occurring lipids.
In its isolated form, however, Sodium Oleate exudes a tallow-like scent and is a white crystalline solid at room temperature.
Sodium Oleate is a useful research chemical.


Sodium Oleate is the sodium salt of oleic acid, a common unsaturated fatty acid found in many animals and plants such as olive oil.
Sodium oleate is a chemical compound that is part of the soap-making process.
Sodium Oleate forms when sodium reacts with animal or vegetable oils and fats.
Sodium oleate has been shown to be thermally stable, which means that it does not break down at high temperatures.


Sodium oleate has been shown to inhibit bacterial growth in culture with a kinetic energy of 75 kJ/mol and an electrochemical impedance spectroscopy (EIS) measurement of 4 MΩ at 10 Hz.
Sodium Oleate also inhibits protein synthesis, leading to cell death by preventing transcription and translation, in experimental models using copper chloride as the catalyst.



USES and APPLICATIONS of SODIUM OLEATE:
In cosmetics, Sodium Oleate is used for its cleansing, thickening and gelling properties.
Sodium oleate is used in soaps and detergents as an emulsifying agent.
Sodium Oleate is also used in the coating of waterproof fabrics.


Sodium Oleate is also used in the manufacture of industrial lubricants.
And in the mining industry, Sodium Oleate is used as a floating agent for minerals.
Sodium Oleate is used in ore flotation, waterproofing textiles, metal polishes, polymer curing, and veterinary medicine.


Sodium Oleate is used as emulsifier for oil/water systems and in the polymerization of butadiene.
Sodium Oleate is used in medicines.
Sodium Oleate is used in the treatment of cholelithiasis.


In various oil based cosmetics, Sodium Oleate is used as cleansing agent, emulsifying agent, surfactant, thickening or gelling agent and viscosity controlling agent.
Sodium Oleate is used in the production of insoluble metallic stearates and industrial lubricants.
Sodium Oleate is also used as textile waterproofing agent.


Sodium Oleate can be operated as anion type surface active agent.
Sodium Oleate can be used as floating agent in mining ore industry.
Sodium Oleate can be used as laboratory reagent in manufacturing of chemicals and other oleates.


Sodium Oleate is widely demanded in the international market due to its high effectiveness, eco-friendliness and purity.
Sodium Oleate is used preparation of Turkey red oil, soft soap and other oleates; in polishing Compounds; waterproofing textiles, oiling wool; manufacture of driers; thickening lubricating oils. Sodium Oleate is used parmaceutic aid (solvent).


Sodium Oleate is used the barium salt in rodent extermination.
Sodium oleate is utilized for a variety of commercial purposes, especially the production of soap.
The soaps made from the fatty acid are considered synthetic although their manufacture only requires a few steps to complete.


Sodium oleate is also often used in the production of insoluble metallic stearates via what is known as the double decomposition method.
Other uses of Sodium Oleate include its inclusion in industrial lubricants and various oil-based cosmetics as a thickening or gelling agent.


Sodium Oleate can be used to measure particle size by using the Langmuir adsorption isotherm technique.
The titration calorimetry technique has also been used to study the thermal stability of Sodium Oleate.
Sodium Oleate is used as anionic surfactant and fabric waterproofing agent.


-Cosmetic Uses:
*cleansing agents
*surfactants
*surfactant - emulsifying
*viscosity controlling agents



CHEMICAL PROPERTIES OF SODIUM OLEATE:
*Sodium Oleate is white powder; slight tallowlike odor.
*Sodium Oleate is soluble in water with partial decom- position; soluble in alcohol.
*Sodium Oleate, white solid, soluble, froth or foam upon shaking the H2O solution (soap), formed by reaction of NaOH and oleic acid (in alcoholic solution) and evaporating.
*Sodium Oleate is used as a source of oleate.



CLASS OF SODIUM OLEATE:
*Specialty Chemicals, Oleochemicals:
Fatty Acids, Fatty Alcohol & more, High Purity Fatty Acids & Esters



WHAT DOES SODIUM OLEATE DO IN A FORMULATION:
*Cleansing
*Emulsifying
*Surfactant
*Viscosity controlling



PROPERTIES OF SODIUM OLEATE:
*Surfactant
*Waterproofing
*Cleaning agent
*Emulsifier
*Floating agent



ALTERNATIVE PARENTS OF SODIUM OLEATE:
*Unsaturated fatty acids
*Carboxylic acid salts
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organic sodium salts
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF SODIUM OLEATE:
*Long-chain fatty acid
*Unsaturated fatty acid
*Carboxylic acid salt
*Organic alkali metal salt
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organic sodium salt
*Organic salt
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



REACTIVITY PROFILE OF SODIUM OLEATE:
Salts, basic, such as Sodium Oleate, are generally soluble in water.
The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0.
They react as bases to neutralize acids.
These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.



ALKALINITY OF SODIUM OLEATE:
take Sodium Oleate and make a solution containing lOmg per lm l with water, and determine it according to law (General rule 0631>, p H value should be 9.0-11. 0.



COLOR OF SODIUM OLEATE:
take Sodium Oleate and make a solution containing lOmg per lm l with water.
Compared with the yellow No. 2 Standard Colorimetric solution (General rule 0901 first method), it should not be deeper.
Sodium Oleate, also known as (9Z)-Octadecanoic acid, is a fatty acid used as an emollient and one of the main components of soap as an emulsifying agent.



PHYSICAL and CHEMICAL PROPERTIES of SODIUM OLEATE:
Molecular Weight: 304.4 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 15
Exact Mass: 304.23782457 g/mol
Monoisotopic Mass: 304.23782457 g/mol
Topological Polar Surface Area: 40.1Ų
Heavy Atom Count: 21
Formal Charge: 0
Complexity: 239
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2

Compound Is Canonicalized: Yes
Chemical Name: Sodium Oleate
CAS Number: 143-19-1
Molecular Formula: C₁₈H₃₃NaO₂
Appearance: White to Off-White Solid
Melting Point: 214-218°C
Molecular Weight: 304.44
Storage: 4°C
Solubility: Methanol (Slightly)
Physical state: solid
Color: white
Odor: No data available
Melting point/freezing point
Melting point/range: 232 - 235 °C - lit.
Initial boiling point and boiling range No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Compound Formula: C18H33NaO2
Molecular Weight: 304.44
Appearance: White powder
Melting Point: 232-235 °C
Boiling Point: N/A
Density: N/A
Solubility in H2O: N/A
Exact Mass: 304.237825 g/mol

Water Solubility: 2.8e-05 g/L
logP: 7.56
logP: 6.78
logS: -7
pKa (Strongest Acidic): 4.99
Physiological Charge: -1
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 0
Polar Surface Area: 40.13 Ų
Rotatable Bond Count: 15
Refractivity: 98.24 m³·mol⁻¹
Polarizability: 36.6 ų
Number of Rings: 0
Bioavailability: No
Rule of Five: No
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No

Melting Point: 235°C
Color: White-Yellow
Quantity: 25 g
Formula Weight: 304.45
Percent Purity: ≥97.0% (T)
Physical Form: Crystalline Powder
Chemical Name or Material: Sodium Oleate
Molecular Formula / Molecular Weight: C18H33NaO2 = 304.45
Physical State (20 deg.C): Solid
Store Under Inert Gas: Store under inert gas
CAS RN: 143-19-1
Reaxys Registry Number: 4046357
PubChem Substance ID: 87574072
Merck Index (14): 6828
MDL Number: MFCD00004438

Melting point: 232-235 °C (lit.)
storage temp.: -20°C
solubility: Methanol (Slightly)
form: Powder
color: White to slightly yellow
Odor: slt tallow odor
Water Solubility: soluble H2O, partially decomposes; soluble alcohol
Merck: 14,6828
BRN: 4046357
Hydrophilic-Lipophilic Balance (HLB): 18
Stability: Stable.
InChIKey: BCKXLBQYZLBQEK-KVVVOXFISA-M
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 232.00 to 235.00 °C. @ 760.00 mm Hg
Boiling Point: 360.00 °C. @ 760.00 mm Hg (est)

Vapor Pressure: 0.000004 mmHg @ 25.00 °C. (est)
Flash Point: 518.00 °F. TCC ( 270.10 °C. ) (est)
logP (o/w): 7.698 (est)
can have "EU Certifcate of freedom from artifical flavor(s)": Yes
Soluble in: water, 5.209 mg/L @ 25 °C (est)
Molecular Formula: CH3(CH2)7CH:CH(CH2)7COONa
Melting Point: 232-235 ℃(lit.)
Boling Point: 360°C at 760 mmHg
Flash Point: 270.1°C
Solubility: Soluble in about 10 parts of water, about 20 parts of ethanol, insoluble in benzene and ether.
Vapor Presure: 3.7E-06mmHg at 25°C
Appearance: White powder
Storage Condition: Room Temprature
Sensitive: Sensitive to light and air
MDL: MFCD00004438



FIRST AID MEASURES of SODIUM OLEATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM OLEATE:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of SODIUM OLEATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM OLEATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of SODIUM OLEATE:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage stability:
Recommended storage temperature: -20 °C
Store under inert gas.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of SODIUM OLEATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
SODIUM OLEATE
143-19-1
Oleic acid sodium salt
Oleic acid, sodium salt
Oleate, sodium
Sodiumoleate
Sodium 9-octadecenoate, (Z)-
16558-02-4
9-Octadecenoic acid (Z)-, sodium salt
sodium (Z)-octadec-9-enoate
sodium;(Z)-octadec-9-enoate
MFCD00004438
CHEBI:81860
399SL044HN
Eunatrol
Olate flakes
CCRIS 1964
HSDB 758
Sodium 9-octadecenoate
EINECS 205-591-0
oleate sodium
9-Octadecenoic acid (9Z)-, sodium salt
9-Octadecenoic acid, sodium salt, (Z)-
UNII-399SL044HN
AI3-19806
sodium (9Z)-octadec-9-enoate
Oleic acid sodium
9-Octadecenoic acid, sodium salt
cis-9-Octadecenoic acid sodium salt
Oleic acidsodium salt
Sodium oleate, >=99%
SCHEMBL3582
C18H33NaO2
SODIUM OLEATE [HSDB]
SODIUM OLEATE [INCI]
SODIUM OLEATE [MART.]
SODIUM OLEATE [WHO-DD]
CHEMBL3527599
DTXSID7021077
HY-N1446B
OLEATE SODIUM [GREEN BOOK]
OLEIC ACID SODIUM SALT [MI]
Sodium oleate, >=98.5% (GC)
AKOS017345104
Sodium oleate, >=95% (capillary GC)
AS-10421
E-470(II)OLEIC ACID, SODIUM SALT
CS-0107318
INS-470(II)OLEIC ACID, SODIUM SALT
O0057
C18601
INS NO.470(II)OLEIC ACID, SODIUM SALT
9-Octadecenoic acid (9Z)-, sodium salt (1:1)
A885003
Q17397737
Oleic acid sodium
9-cis-Octadecenoic acid sodium
9Z-Octadecenoic acid sodium
cis-9-Octadecenoic acid sodium salt, Oleic acid sodium salt
Oleic Acid, Sodium Salt
9-Octadecenoic Acid (9Z)-, Sodium Salt (1:1)
9-Octadecenoic Acid (9Z)-, Sodium Salt
9-Octadecenoic Acid (Z)-, Sodium Salt
Sodium Oleate; Olate Flakes
Eunatrol
Oleic acid, Sodium salt
9 -Octadecenoic acid sodium salt
9-Octadecenoic acid (9Z)-, sodium salt (1:1)
9-Octadecenoic acid, sodium salt
Osteum
Sodium 9-octadecenoate
9-Octadecenoic acid (Z)-, sodium salt
Eunatrol
Olate flakes
Oleic acid, sodium salt
Sodium 9-octadecenoate, (Z)-
Approx
SODIUM OLEATE POWDER
eunatrol
Lunac SO 90L
Nonsoul ON-A
NPS Red Oil Soap
Sodium oleate, 98%, for synthesis
osteum
Sodium oL
olateflakes
Osteum
SODIUM OLEATE
Oleic acid sodium salt
Sodium 9-octadecenoate
(9Z)-octadec-9-enoic acid
sodium (9E)-octadec-9-enoate
sodium (9Z)-octadec-9-enoate
9-Octadecenoic acid, sodium salt
9-Octadecenoic acid (Z)-, sodium salt

SODIUM OLEATE = OLEIC ACID SODIUM SALT


CAS Number: 143-19-1
EC Number: 205-591-0
MDL number: MFCD00004438
Molecular Formula: C18H33NaO2


Sodium Oleate is a sodium salt of oleic acid.
Sodium oleate is an organic molecular entity.
Sodium Oleate is a light tan solid with a slight tallow-like odor.
Sodium Oleate sinks and mixes slowly with water.


Sodium Oleate is classified under CAS No.143-19-1.
Sodium Oleate is also known as Oleic Acid Sodium Salt, Sodium Salt of Oleic Acid.
Sodium Oleate occurs as a white to yellowish powder or as light brown yellow coarse powder or lumps.
Sodium Oleate has characteristic odor & taste.


Sodium Oleate is soluble in alcohol and water.
Sodium Oleate is a major component of soap as emulsifying agent.
In hepatocytes, Sodium Oleate activates Protein Kinase C (PKC).
Sodium Oleate is white powder; slight tallowlike odor.


Sodium Oleate is soluble in water with partial decom- position; soluble in alcohol.
Sodium Oleate is the sodium salt of oleic acid.
Sodium Oleate functions as a binder, emulsifier, and anticaking agent.
Sodium Oleate is derived from natural fats and oils.


Sodium Oleate is a light tan solid with a slight tallow-like odor.
Sodium Oleate sinks and mixes slowly with water.
Air & Water Reactions of Sodium Oleate: Sodium Oleate is water soluble.
Sodium Oleate gives basic aqueous solution.


Sodium oleate (cas# 143-19-1) is a useful research chemical.
Sodium Oleate is an unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature.
Sodium Oleate is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent.
Sodium oleate is a yellowish powder, white or light brown yellow granular powder or lump with unusual characteristic taste and odor.


Sodium Oleate is the sodium salt of oleic acid, a common unsaturated fatty acid, which is found in many animals and plants.
Sodium oleate is not found freely in nature; however, it occurs as a part of complex naturally occurring lipids.
Sodium oleate have a tallow-like scent in its isolated form and is white crystalline solid at a room temperature.
This unsaturated fatty acid resembles a long-chain hydrocarbon tail due to a double bond.


Sodium Oleate (NaC18H33O2) is an organic additive which is the sodium “salt” of oleic acid.
Sodium Oleate comes as a powder of small, yellowish crystals that dissolve in water and alcohol.
Sodium Oleate (C18H33O2Na, CAS Reg. No. 143-19-1) is the sodium salt of oleic acid (cis-9-octadecenoic acid).
Sodium Oleate exists as a white to yellowish powder with a slight tallow-like odor.


Commercially, Sodium Oleate is made by mixing and heating flaked sodium hydroxide and oleic acid.
Sodium Oleate is a surfactant for nanomaterial synthesis.
Sodium Oleate, also known as (9Z)-Octadecanoic acid, is a fatty acid used as an emollient and one of the main components of soap as an emulsifying agent.


Sodium oleate is a chemical compound that is part of the soap-making process.
Sodium Oleate forms when sodium reacts with animal or vegetable oils and fats.
Sodium oleate has been shown to be thermally stable, which means that it does not break down at high temperatures.
Sodium Oleate is the sodium salt of oleic acid, a common unsaturated fatty acid found in many animals and plants such as olive oil.


Sodium oleate, also known as sodium oleic acid, belongs to the class of organic compounds known as long-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms.
Sodium oleate is a weakly acidic compound (based on its pKa).
Sodium Oleate is a Sodium soap of Oleic acid.


Sodium Oleate is available in paste and liquid forms.
Sodium oleate is Water soluble and gives a transparent solution with distilled water.
Sodium oleate has a double bond at the middle of its long carbon chain.
Therefore, Sodium oleate shows cis-trans geometry.


Sodium oleate also contains a carboxylic acid group, which makes the molecule hydrophilic and long carbon chain makes the compound hydrophobic.
In aqueous solutions, Sodium Oleate forms a slightly alkaline pH upon dissolution.
Sodium oleate is an organic compound having the chemical formula C18H33NaO2.
Sodium oleate appears as a light tan solid at room temperature.


Sodium oleate has a slight tallow-like odour.
Sodium oleate is the sodium salt of oleic acid.
Therefore, Sodium oleate contains a sodium cation and the conjugate base of oleic acid; oleate anion.
Sodium oleate can mix with water slowly.


Sodium oleate is white to yellowish powder and lumps.
Sodium oleate is soluble in warm water, slightly soluble in 90% ethanol.
Sodium oleate is slightly like butter.
The aqueous solution is alkaline due to hydrolysis, but the alcohol solution is not hydrolyzed.


Sodium oleate has good solubility in hot water, the aqueous solution is light yellow and transparent, alkaline, soluble in ethanol, and the solution is neutral; it is slowly oxidized in the air to darken the color.
As a fatty acid, Sodium Oleate is not generally found free in nature, but rather occurs as a component of more complex naturally occurring lipids.


In Sodium Oleate's isolated form, however, the substance exudes a tallow-like scent and is a white crystalline solid at room temperature.
Sodium oleate is an unsaturated fatty acid that features a kink in the long-chain hydrocarbon tail of its molecules due to a cis double bond.
Though the biochemical is already being utilized for a variety of applications, scientists are currently investigating the fatty acid in hopes of coming to a better understanding of Sodium Oleate and finding additional uses for it.



USES and APPLICATIONS of SODIUM OLEATE:
Using Sodium Oleate in combination with a chelating reagent like dimethyl glyoxime or a -diphenyl glyoxime the floatability of garnierite mineral could be markedly increased to around 80% in alkaline region between pH11 and 12
Sodium Oleate is one of numerous organometallic compounds sold by American Elements.
Sodium Oleate is used in the treatment of cholelithiasis.


Organometallics are useful reagent, catalyst, and precursor materials with applications in thin film deposition, industrial chemistry, pharmaceuticals, LED manufacturing, and others.
Sodium Oleate is used in medicines.
In various oil based cosmetics, Sodium Oleate is used as cleansing agent, emulsifying agent, surfactant, thickening or gelling agent and viscosity controlling agent.


Sodium Oleate is used in the production of insoluble metallic stearates and industrial lubricants.
Sodium Oleate is also used as textile waterproofing agent.
Sodium Oleate can be operated as anion type surface active agent.
Sodium Oleate can be used as floating agent in mining ore industry.


Sodium Oleate can be used as laboratory reagent in manufacturing of chemicals and other oleates.
Sodium Oleate is white solid, soluble, froth or foam upon shaking the H2O solution (soap), formed by reaction of NaOH and oleic acid (in alcoholic solution) and evaporating.
Sodium Oleate is used as a source of oleate.


Sodium Oleate is used in ore flotation, waterproofing textiles, metal polishes, polymer curing, and veterinary medicine.
Sodium Oleate is used as emulsifier for oil/water systems and in the polymerization of butadiene.
Sodium Oleate is used preparation of Turkey red oil, soft soap and other oleates; in polishing Compounds; waterproofing textiles, oiling wool; manufacture of driers; thickening lubricating oils.


Sodium Oleate is used Pharmaceutic aid (solvent).
Sodium Oleate is used as barium salt in rodent extermination.
Sodium Oleate is a mild cleansing and foaming agent generally used in soaps.
Sodium Oleate is used as an industrial lubricant.


Sodium Oleate is utilized as a thickening agent in cosmetics or as a gelling agent in beauty products.
Sodium oleate is employed as an emulsifier in soaps.
Sodium Oleate is also used in medicines for the treatment of cholelithiasis.
Sodium oleate is used as a cleaning agent, surfactant, viscosity controlling agent and emulsifier in various oil-based cosmetics.


Sodium oleate is employed in the production of metallic acids.
Sodium Oleate is utilized in the textile industry as a waterproofing agent.
Sodium Oleate is used as a floating agent in the mining industry.
Sodium Oleate is employed as a laboratory reagent in the chemical industry.


Sodium oleate can be used to measure particle size by using the Langmuir adsorption isotherm technique.
The titration calorimetry technique has also been used to study the thermal stability of this compound.
Sodium oleate has been shown to inhibit bacterial growth in culture with a kinetic energy of 75 kJ/mol and an electrochemical impedance spectroscopy (EIS) measurement of 4 MΩ at 10 Hz.


Sodium Oleate also inhibits protein synthesis, leading to cell death by preventing transcription and translation, in experimental models using copper chloride as the catalyst.
Sodium oleate is used to investigate effects on apolipoprotein B synthesis, degradation and secretion in cultured cells.
Sodium oleate is used as anionic surfactant and fabric waterproofing agent


In the food industry, sodium oleate is used as a stabilizer or as a thickener.
Sodium Oleate is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues.
Sodium Oleate prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation.
Sodium Oleate inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines.


Sodium Oleate is primarily used in Construction Chemicals for manufacturing of Cement Admixtures.
Sodium Oleate is also be used as rubber foaming agent, detergent, lubricant, and catalyst.
Sodium Oleate can also be used in Submersibles.
Sodium Oleate is also a consumer in the production of the cleansing agent in household cleaning products.


Sodium Oleate is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues.
Sodium Oleate prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation.
Sodium Oleate inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines.


Sodium Oleate is used in mineral processing, waterproof fabric, soap, and serve as a anionic surfactant and fabric waterproofing agent;
Analysis of pure Sodium Oleate (AR) is used to activate protein kinase C in liver cells.
Sodium Oleate is utilized for a variety of commercial purposes, especially the production of soap.
The soaps made from the fatty acid are considered synthetic although their manufacture only requires a few steps to complete.
Sodium oleate is also often used in the production of insoluble metallic stearates via what is known as the double decomposition method.
Other uses of Sodium Oleate include its inclusion in industrial lubricants and various oil-based cosmetics as a thickening or gelling agent.


-Uses of Sodium Oleate :
*In cosmetics, sodium oleate is used for its cleansing, thickening and gelling properties. Sodium oleate is used in soaps and detergents as an emulsifying agent.
*It is also used in the coating of waterproof fabrics.
*Sodium oleate is also used in the manufacture of industrial lubricants.
*And in the mining industry, as a floating agent for minerals.



SODIUM OLEATE MARKET:
The global sodium oleate market is driven by the rise in demand from plastic and rubber processing industries.
Additionally, rise in use of sodium oleate as an ingredient for soap manufacturing is expected to propel the global market.
However, stringent regulation imposed by governments across the globe is likely to restrain the sodium oleate market.
In terms of application, the Sodium Oleate market can be segregated into lubricants, preservatives, surface cleaning agents, flotation agents, emulsifiers, waterproofing agents, thickening agents, gelling agents, and others.

Based on region, the global sodium oleate market can be divided into North America, Asia Pacific, Europe, Latin America, and Middle East & Africa.
Asia Pacific is expected to dominate the market due to high demand for sodium oleate from cosmetics and chemical industries.
The Sodium Oleate market in countries such as China, India, and Japan is estimated to expand at significant pace in the near future.

China is expected to be a key producer of sodium oleate due to the rise in its demand from construction, pharmaceutical, textile, and personal care industries.
The market in the North America is estimated to expand due to high demand for sodium oleate from end-use industries such as pharmaceutical and personal care in the U.S. and Canada.
The market in Europe is projected to expand at a substantial pace due to high demand for sodium oleate from the pharmaceutical industry.
The sodium oleate market in Latin America and Middle East & Africa is anticipated to expand at a sluggish pace during the forecast period.



SODIUM OLEATE MARKET: KEY SEGMENTS
Based on product, the sodium oleate market can be segmented into paste, liquid, and powder.
Sodium oleate paste is used in construction chemicals for manufacturing cement mixtures.
The powder form is used as a binder and polishing compound, while the liquid sodium oleate is used in as an emulsifier and anticaking agent.



FEATURES AND BENEFITS of SODIUM OLEATE:
*Sodium Oleate acts like surfactants and reduces the surface tension of a liquid and prevents the ingredients in the products from separating into dispersed chemicals.
*Sodium Oleate acts as a plasticizer.
*Sodium Oleate has no “creaming” effect.



PROPERTIES of SODIUM OLEATE:
– Surfactant
– Waterproofing
– Cleaning agent
– Emulsifier
– Floating agent



ALTERNATIVE PARENTS of SODIUM OLEATE:
*Unsaturated fatty acids
*Carboxylic acid salts
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Organic sodium salts
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS of SODIUM OLEATE:
*Long-chain fatty acid
*Unsaturated fatty acid
*Carboxylic acid salt
*Organic alkali metal salt
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organic sodium salt
*Organic salt
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



WHAT DOES SODIUM OLEATE DO IN A FORMULATION?
*Cleansing
*Emulsifying
*Surfactant
*Viscosity controlling



WHAT IS THE DIFFERENCE BETWEEN SODIUM STEARATE AND SODIUM OLEATE?
Sodium stearate is an organic compound having the chemical formula C18H35NaO2 while Sodium Oleate is an organic compound having the chemical formula C18H33NaO2.
The key difference between sodium stearate and sodium oleate is that sodium stearate is the sodium salt of stearic acid, whereas sodium oleate is the sodium salt of oleic acid.
Furthermore, sodium stearate is a white solid while sodium oleate is a slightly tan solid.



SODIUM STEARATE VS SODIUM OLEATE
Sodium stearate and sodium oleate are sodium salts of two different acid compounds.
The key difference between sodium stearate and sodium oleate is that sodium stearate is the sodium salt of stearic acid, whereas sodium oleate is the sodium salt of oleic acid.



PHYSICAL and CHEMICAL PROPERTIES of SODIUM OLEATE:
Molecular Weight: 304.44
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 15
Exact Mass: 304.23782457
Monoisotopic Mass: 304.23782457
Topological Polar Surface Area: 40.1 Ų
Heavy Atom Count: 21
Formal Charge: 0
Complexity: 239
Isotope Atom Count: 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 1
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Color: White-Yellow
Melting Point: 235°C
Quantity: 25g
Formula Weight: 304.45
Physical Form: Crystal-Powder at 20°C
Percent Purity: ≥97.0% (T)
Chemical Name or Material: Sodium Oleate
Compound Formula: C18H33NaO2
Molecular Weight: 304.44
Appearance: White powder
Melting Point: 232-235 °C
Boiling Point: N/A
Density: N/A

Solubility in H2O: N/A
Exact Mass: 304.237825 g/mol
Physical state: solid
Color white
Odor: No data available
Melting point/freezing point:
Melting point/range: 232 - 235 °C - lit.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decompositio temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Melting point: 232-235 °C (lit.)

storage temp.: -20°C
solubility: Methanol (Slightly)
form: Powder
color: White to slightly yellow
Odor: slt tallow odor
Water Solubility: soluble H2O, partially decomposes; soluble alcohol
Merck: 14,6828
BRN: 4046357
Hydrophilic-Lipophilic Balance (HLB): 18
Stability: Stable.
Min. Purity Spec: 97%
Physical Form (at 20°C): Solid

Melting Point: 220-230°C
Long-Term Storage: Store long-term in a cool, dry place
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 232.00 to 235.00 °C. @ 760.00 mm Hg
Boiling Point: 360.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000004 mmHg @ 25.00 °C. (est)
Flash Point: 518.00 °F. TCC ( 270.10 °C. ) (est)
logP (o/w): 7.698 (est)
Soluble in: water, 5.209 mg/L @ 25 °C (est)



FIRST AID MEASURES of SODIUM OLEATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM OLEATE:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of SODIUM OLEATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM OLEATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of SODIUM OLEATE:
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage stability:
Recommended storage temperature: -20 °C
Store under inert gas.



STABILITY and REACTIVITY of SODIUM OLEATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
SODIUM OLEATE
143-19-1
Oleic acid sodium salt
Osteum
Oleic acid, sodium salt
Oleate, sodium
Sodiumoleate
Sodium 9-octadecenoate, (Z)-
16558-02-4
9-Octadecenoic acid (Z)-, sodium salt
sodium (Z)-octadec-9-enoate
CHEBI:81860
399SL044HN
Eunatrol
Olate flakes
MFCD00004438
CCRIS 1964
HSDB 758
Sodium 9-octadecenoate
EINECS 205-591-0
oleate sodium
9-Octadecenoic acid (9Z)-, sodium salt
9-Octadecenoic acid, sodium salt, (Z)-
sodium (Z)-octadec-9-enoate
UNII-399SL044HN
AI3-19806
sodium (9Z)-octadec-9-enoate
Oleic acid sodium
9-Octadecenoic acid, sodium salt
cis-9-Octadecenoic acid sodium salt
Oleic acidsodium salt
Sodium oleate, >=99%
SCHEMBL3582
SODIUM OLEATE
CHEMBL3527599
DTXSID7021077
HY-N1446B
OLEATE SODIUM
OLEIC ACID SODIUM SALT
Sodium oleate, >=98.5% (GC)
AKOS017345104
Sodium oleate, >=95% (capillary GC)
AS-10421
E-470(II)OLEIC ACID, SODIUM SALT
CS-0107318
INS-470(II)OLEIC ACID, SODIUM SALT
O0057
C18601
INS NO.470(II)OLEIC ACID, SODIUM SALT
9-Octadecenoic acid (9Z)-, sodium salt (1:1)
A885003
Q17397737
Sodium oleate, >=82% fatty acids (as oleic acid) basis, powder
Oleic acid sodium
9-cis-Octadecenoic acid sodium
9Z-Octadecenoic acid sodium
Osteum
SODIUM OLEATE
Oleic acid sodium salt
Sodium 9-octadecenoate
(9Z)-octadec-9-enoic acid
sodium (9E)-octadec-9-enoate
sodium (9Z)-octadec-9-enoate
9-Octadecenoic acid, sodium salt
9-Octadecenoic acid (Z)-, sodium salt
Approx
SODIUM OLEATE POWDER
eunatrol
Lunac SO 90L
Nonsoul ON-A
NPS Red Oil Soap
Sodium oleate, 98%, for synthesis
osteum
Sodium oL
olateflakes
9-Octadecenoic acid, sodium sal
Osteum
Sodium 9-octadecenoate
9-Octadecenoic acid (Z)-, sodium salt
Eunatrol
Olate flakes
Oleic acid, sodium salt
Sodium 9-octadecenoate, (Z)-
Oleic Acid, Sodium Salt
9-Octadecenoic Acid (9Z)-, Sodium Salt (1:1)
9-Octadecenoic Acid (9Z)-, Sodium Salt
9-Octadecenoic Acid (Z)-, Sodium Salt
Sodium Oleate; Olate Flakes
Eunatrol
9-Octadecenoic acid, sodium salt
Oleic acid sodium salt
osteom
Sodium 9-octadecenoate
9-Octadecenoic acid (Z)-, sodium salt
(9Z)-octadec-9-enoic acid
sodium (9Z)-octadec-9-enoate
sodium (9E)-octadec-9-enoate
Sodium oleate
Sodium (9Z)-octadec-9-enoate
9-Octadecenoic acid, sodium salt, (9Z)- (1:1)
143-19-1
Oleate, sodium
9-Octadecenoic acid (9Z)-, sodium salt
(Z)-9-Octadecenoic acid sodium salt
9-Octadecenoic acid (9Z)-, sodium salt (1:1)
9-Octadecenoic acid (Z)-, sodium salt
9-Octadecenoic acid, sodium salt, (Z)-
Eunatrol
Lunac SO 90L
Natriumoleat
Nonsoul ON 1
Nonsoul ON-A
NPS Red Oil Soap
Olate Flakes
Oleate de sodium
oleato de sodio
Oleic acid, sodium salt
Pionin D 951P
EINECS 205-591-0
Sodium 9-octadecenoate, (Z)-
UNII-399SL044HN

SODIUM OLEOYL SARCOSINATE N° CAS : 14351-62-3 Nom INCI : SODIUM OLEOYL SARCOSINATE N° EINECS/ELINCS : 238-312-6

SODIUM OLETH SULFATE N° CAS : 27233-34-7 "Pas terrible" dans toutes les catégories. Nom INCI : SODIUM OLETH SULFATE Classification : Sulfate, Composé éthoxylé Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Agent moussant : Capture des petites bulles d'air ou d'autres gaz dans un petit volume de liquide en modifiant la tension superficielle du liquide Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

E 232; o-phenylphenol sodium salt; SODIUM O-PHENYLPHENATE; Sodium-o-phenylphenate; Sodium-o-phenylphenol; SOPP; N° CAS : 132-27-4 - Orthophénylphénate de sodium; Origine(s) : Synthétique. Nom INCI : SODIUM O-PHENYLPHENATE; Nom chimique : Sodium 2-biphenylate; N° EINECS/ELINCS : 205-055-6; Additif alimentaire : E232. Classification : Règlementé, Conservateur. Ses fonctions (INCI); Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes; Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.Principaux synonymes; Noms français : (1,1'-Biphenyl)-2-ol, sodium salt; 2-BIPHENYLOL, SODIUM SALT; 2-HYDROXYDIPHENYL SODIUM; 2-HYDROXYDIPHENYL, SODIUM SALT; 2-PHENYL PHENOL, SODIUM SALT; 2-Phényl phénol, sel de soude; o-phenylphenol sodium salt; o-Phénylphénate de sodium; Ortho-phénylphénate de sodium; Phénylphénate de sodium (ortho-); SODIUM 2-BIPHENOLATE; SODIUM 2-BIPHENYLOLATE; SODIUM 2-HYDROXYDIPHENYL; SODIUM 2-PHENYLPHENATE; Sodium o-phenylphenate; Sodium o-phenylphenol; Sodium o-phenylphenolate; SODIUM O-PHENYLPHENOXIDE; SODIUM ORTHO PHENYLPHENATE; SODIUM ORTHO-PHENYLPHENATE; SODIUM SALT OF O-PHENYLPHENOL; Sodium, 2-phényl phénolate de; Sodium, phénylphénate de (ortho-). Noms anglais : o-phenol, sodium salt; Sodium-2-phenylphenolate. Utilisation et sources d'émission: Fabrication de germicides, fabrication de fongicides; 2-phenylphenol, sodium salt ; sodium 2-biphenylate; 2-phenylphenol, sodium salt; Sodium orthophenylphenoxide. Translated names; 2-Bifenilat de sodiu (ro); 2-Bifenilat tas-sodju (mt); 2-Bifenilato de sodio (es); 2-Bifenilato de sódio (pt); 2-bifenilato di sodio (it); 2-bifenylan sodu (pl) ; 2-bifenylát sodný (cs); 2-biphénylate de sodium (fr); 2-fenil-fenol, natrijeva sol (hr); 2-fenilfenol, natrijeva sol (sl); 2-fenilfenol, nátriumsó (hu); 2-fenilfenola nātrija sāls (lv); 2-fenilfenolis, natrio druska (lt); 2-fenilfenolo, sale di sodio (it); 2-fenylfenol, natriumsalt (no); 2-fenylofenolan sodu (pl); 2-Fenyylifenolin natriumsuola (fi); 2-fenüülfenool, naatriumi sool (et); 2-διφαινυλικό νάτριο (el) ; 2-фенилфенол, натриева сол (bg); bifenyl-2-olan sodu (pl); Naatrium-2-bifenülaat (et); Natrijev 2-bifenilat (hr); Natrio 2-bifeniliatas (lt); Natrium 2-biphenylat (de); Natrium-2-bifenylaat (nl) ; Natrium-2-bifenylaatti (fi); natrium-2-bifenylat (no); natrium-2-biphenylat (da); natrium-bifenyl-2-olát (cs); natriumbifenyl-2-yloksid (no); natriumbifenyl-2-yloxide (nl); natriumbiphenyl-2-yloxid (da) ; Nátrium-2-bifenilát (hu); nátrium-2-bifenylát (sk); nátrium-bifenyl-2-olát (sk); Nātrija 2-bifenilāts (lv); o-Phenylphenol (de); orthophénylphénate de sodium (fr); sare de 2-fenilfenol, sodiu (ro); sodio 2-bifenilato (it); sodiu 2-bifenilat (ro); Sodium 2-biphenylate (no); sodná soľ bifenyl-2-olu (sk); óxido de sodio y de bifenil-2-ilo (es); διφαινυλ-2-υλικό νάτριο (el); Натриев 2-бифенилат (bg); CAS names; [1,1'-Biphenyl]-2-ol, sodium salt (1:1). IUPAC names: (1,1'-Biphenyl)-2-ol, sodium salt, tetrahydrate; (2-biphenylyloxy)sodium; 2-Phenylphenol Sodium Salt Tetrahydrate; Sodium 2 biphenylate; sodium 2-phenylphenolate; sodium biphenyl-2-olate; sodium;2-phenylphenolate; [1,1'-Biphenyl]-2-ol, sodium salt (1:1) [ACD/Index Name]; 132-27-4 [RN]; 205-055-6 [EINECS] ; 2-Biphénylolate de sodium [French] ; Natrium-2-biphenylolat [German] ; natriumbiphenyl-2-olat [German]; o-Phenylphenol sodium; o-Phenylphenol sodium salt; Sodium 2-biphenylolate ; [ACD/IUPAC Name]; Sodium biphenyl-2-olate; sodium o-phenylphenate; sodium o-phenylphenoxide; sodium ortho-phenylphenate; (1,1'-Biphenyl)-2-ol, sodium salt; (1,1'-Biphenyl)-2-ol, sodium salt (1:1); (2-biphenylyloxy)sodium; (2-biphenylyloxy)-Sodium; [1,1'-Biphenyl]-2-ol, sodium salt; [132-27-4]; 2-Bi phenylol, Sodium Salt; 2-Biphenylol sodium salt; 2-Biphenylol, Sodium Salt 2-hydroxybiphenyl sodium salt; 2-Hydroxydiphenyl sodium; 2-Hydroxydiphenyl sodium salt; 2-Hydroxydiphenyl, sodium salt; 2-PHENYL PHENOL SODIUM; 2-phenylphenol sodium ; 2-Phenylphenol Sodium Salt; 2-PHENYLPHENOL, SODIUM SALT; AGN-PC-0H22NM; bactrol; Biphenylol, sodium salt; BR-73024; D.C.S; D.C.S.; dorvicide a; Dowicide; Dowicide A ; Dowicide A & A flakes; Dowicide A Flakes; dowizid; Dowizid A; E232; EINECS 205-055-6; Hydroxydip henyl, sodium salt; Hydroxydiphenyl, sodium salt; MFCD00002209 [MDL number] ; mil-du-rid; Mystox WFA; natriphene; o-Phenyl phenol sodium salt; o-Phenylphenate sodium; o-Phenylphenate, sodium; O-Phenylphenol, na salt; o-Phenylphenol, sodium; o-Phenylphenol, sodium salt; OPP-NA; OPP-sodium; orphenol; Phenylphenol, sodium salt; Preventol ON & ON Extra; Preventol ON extra; preventolon; Preventol-ON; SCHEMBL249962; Sodium (1,1'-biphenyl)-2-olate ; Sodium [1,1`-biphenyl]-2-olate; Sodium [1,1'-biphenyl]-2-olate; Sodium 2-biphenylate; Sodium 2-hydroxydiphenyl; sodium 2-phenylbenzen-1-olate; sodium 2-phenylbenzenolate;Sodium 2-phenylphenate; sodium 2-phenylphenolate; sodium 2-phenylphenoxide; Sodium o-phenylphenol; sodium o-phenylphenolate; Sodium o-phenylphenyolate; Sodium orthophenylphenoxide ; Sodium, (2-biphenylyloxy)-; sodium;2-phenylphenolate; Sodium[1,1'-biphenyl]-2-olate; Sodium-2-biphenylate; Sodium-o-phenylphenate; Sodium-o-phenylphenol; SOPP; stopmold b ; Topane

Sodium Omadine Sodium Omadine is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, Sodium Omadine appears to interfere with membrane transport ultimately leading to a loss of metabolic control. Metalworking fluids are fertile breeding grounds for microorganisms, particularly bacteria and fungi. Their unchecked growth causes fluids to deteriorate and degrades the fluid performance; this in turn causes damage to the work piece, cutting tools and fluid handling systems. Growth of microorganisms in fluids can also affect workers by causing foul odors, skin irritation and allergic reactions. These problems can be reduced or eliminated through the proper use of an antimicrobial agent. Sodium omadine 2000 Antimicrobial is a proprietary blend based on the antimicrobial active, sodium pyrithione (CAS # 3811-73-2) a fungicidal product with a successful history of use by the metalworking industry. Sodium omadine 2000 Antimicrobial exhibits increased efficacy against a wide variety of microorganisms found in metalworking fluid systems. In addition to its anticipated antifungal performance, Sodium omadine 2000 Antimicrobial also exhibits antibacterial efficacy. The improved antimicrobial performance of Sodium omadine 2000 Antimicrobial is not a result of combinations with formaldehyde-based condensates, phenols, or isothiazoline-based products. This proprietary product is a blend of sodium pyrithione with a potentiator, and an amine coupler. This versatile antimicrobial blend can eliminate the need for formulating with multiple products. Sodium omadine 2000 Antimicrobial provides broad-spectrum antimicrobial control to a variety of metalworking fluid formulations and is suitable for use in both metalworking fluid concentrates and as a post treatment additive. Sodium omadine 2000 Antimicrobial is registered for use with the United States Environmental Protection Agency (US EPA Reg. No. 1258-1238) under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), for use in metalworking, cutting, cooling and lubricating concentrates and end-use fluids. If you are considering another use, please consult with an Arch Chemicals, Inc. representative. It is a violation of Federal law to use an antimicrobial agent in an application for which it does not have EPA registration. Sodium omadine 2000 AnTIMICROBIAL HAS THE FOLLOWInG PRODUCT ATTRIBUTES. Sodium pyrithione, % 10.0 Form Liquid Color Medium yellow Odor Amine pH @ 10% 11-12 Density@25°C 1.12 ADDRESSInG THE BLUE COLOR PROBLEM Metalworking fluids have been known to change color upon the addition of pyrithione-based biocides. This is often referred to as the ‘blue-color problem’. The color change is due to the presence of ionic iron, which combines with pyrithione to form a highly colored, water insoluble compound. Iron can be introduced through raw materials, dilution water, or certain metalworking fluid operations. In the case of metalworking fluid concentrates, while the levels of ionic iron present are usually low, typically in the range of 5-25 ppm (parts per million), addition of sodium pyrithione will discolor the formulation, turning it gray or at times black. One method for addressing this problem is through the use of iron specific sequestering agents, like ethylenediaminetetraacetic acid (EDTA) or Arch’s Wayhib RW Chelating Agent. A more chronic problem for pryithione-based biocides is with high-speed cast iron machining operations. Metalworking fluid formulations used in these operations tend to accumulate and maintain high levels of ionic iron, making the use of sodium pyrithione unsuitable. In controlled laboratory tests dilute metalworking fluids known to contain 100-150 ppm of ironic iron did not discolor. In addition, this proprietary new antimicrobial can be used in formulations, which accumulate and maintain high levels of iron, while in use. Additions of Sodium omadine 2000 Antimicrobial to dilute metalworking fluids known to contain ionic iron in the range of 100-150 ppm did not turn blue, and the antimicrobial performance remains intact. AnTIMICROBIAL ACTIVITY Below is a summary of data obtained using a test designed to evaluate the effectiveness of Sodium omadine 2000 Antimicrobial in three types of metalworking fluid formulations. The test protocol calls for one hundred milliliters of appropriately diluted fluid (20:1) to be placed into two hundred fifty milliliter Erlenmyer flasks. Sodium omadine 2000 Antimicrobial is added to each flask at the onset of the experiment. The treatment level used for this experiment was 1000 ppm, product as sold. Flasks are maintained at ambient temperature on an orbital shaker and challenged 3 times a week with a mixed inoculum of bacteria and fungi. RECOMMEnDED USE LEVELS The recommended use level for Sodium omadine 2000 Antimicrobial in metalworking fluid concentrates (typically used at 20:1) is between 2.0-4.0%, product as sold. Post treatment dose levels of 1000-3000 ppm, product as sold, have been shown to be very effective in dilute metalworking fluids. The Following United States EPA Guidelines Should be Followed When Using This Biocide: TO INHIBIT THE GROWTH OF FUNGI AND BACTERIA IN AQUEOUS METALWORKING, CUTTING, COOLING AND LUBRICATING FLUIDS: Add up to 5000 parts per million (0. 5% v/v) of Sodium omadine 2000 Antimicrobial to the diluted fluid (5.0 gals per 1000 gals). When adding fresh diluted fluid to compensate for dragout or other losses, add Sodium omadine 2000 Antimicrobial to makeup fluid according to the above directions. Frequent checks (at least once per week) of the bacterial and fungal population in the system should be made using standard microbiological plate count procedures or any of the commercial "dip-stick" type devices. When the bacterial count reaches 105 and/or the fungal count reaches 102 organisms per milliliter, add additional Sodium omadine 2000 Antimicrobial according to the above directions. The fluid should be checked at least once per day with a refractometer (or other suitable means) to determine if water loss by evaporation has occurred. Make-up water should be added daily to compensate for such losses. The fluid should be monitored at least once per week (depending on the metalworking operation involved) for the following: tramp oil, pH, odor, oil droplet size, and anticorrosion properties. If any of these parameters is outside the specifications established for the system in question, they should be brought up to specifications by the addition of suitable additives or the fluid should be discarded and replaced after cleaning the system. Add Sodium omadine 2000 Antimicrobial to the fresh fluid according to the above directions. Contaminated fluid systems should be cleaned prior to the addition of Sodium omadine 2000 Antimicrobial. Drain the system, clean with a cleaner designed for this purpose, rinse with water, and refill with fresh fluid. Sodium omadine 2000 Antimicrobial may be added to the fluid at the time it is prepared (diluted) or to the reservoir (sump) containing the fluid after it is put into use. If it is added to the reservoir, the fluid should be circulated after addition to ensure mixing. LIGHT STABILITY Sodium omadine 2000 Antimicrobial will gradually degrade when exposed to UV light. Formulations containing Sodium omadine 2000 Antimicrobial should be packaged in brown or opaque containers unless tests have shown that photodegradation is not a problem. PH STABILITY Sodium omadine 2000 Antimicrobial is effective over the pH range typical of most metalworking fluids. Below pH 4.5, the sodium salt is in equilibrium with free pyrithione and while pyrithione is microbiologically active, it is very unstable in the presence of light or oxygen. CHEMICAL REACTIVITY Oxidizing agents (such as peroxides and hypohalites) will convert pyrithione first to dipyrithione (2,2'-dithiobis-pyridine-1, 1'- dioxide), which is microbiologically active, and finally to pyrithione sulfinic or sulfonic acid, which are not microbiologically active compounds. SAFETY InFORMATIOn Material Safety Data Sheets containing appropriate health and safety advice on Sodium omadine 2000 Antimicrobial are available from your nearest regional office. PACKAGInG Sodium omadine 2000 Antimicrobial is available from Rochester, NY in 45lb. And 500 lb. Containers and is available from Swords, Republic of Ireland in a 226.8 kg container. To place an order, call our order fulfillment group at 770-805-3301. APPLICATIOn For product application and formulation information please refer to Sodium omadine 2000 Antimicrobial product labeling. Directions for Use of Sodium omadine To inhibit the growth of fungi in aqueous metalworking, cutting, cooling and lubricating fluids: Add up to 1250 ppm (0.125% v/v) of Sodium omadine fungicide to the diluted fluid (1.25 gal per 1000 gal of solution). Typical recommended dose levels are between 200 and 500 ppm, product as sold. Different use and contamination conditions may require different levels of Sodium omadine fungicide and while compatible with most metalworking fluids physical and chemical compatibility testing is recommended. When adding fresh diluted fluid to compensate for dragout or other losses, add Sodium omadine fungicide to make-up fluid according to the above directions. Frequent checks (at least once per week) of the bacterial and fungal population in the system should be made using standard microbiological plate count procedures or any of the commercial “dip-stick” type devices. When the fungal count reaches 102 organisms per milliliter or greater, add additional Sodium omadine fungicide according to the above directions. The fluid should be checked at least once per day with a refractometer (or other suitable means) to determine if water loss by evaporation has occurred. Make-up water should be added daily to compensate for such losses. The fluid should be monitored at least once per week (depending on the metalworking operation involved) for the following: tramp oil, pH, odor, oil droplet size, and anticorrosion properties. If any of these parameters is outside the specifications established for the system in question, they should be brought up to specifications by the addition of suitable additives or the fluid should be discarded and replaced after cleaning the system. Add Sodium omadine fungicide to the fresh fluid according to the above directions. Contaminated fluid systems should be cleaned prior to the addition of Sodium omadine fungicide. Drain the system, clean with a cleaner designed for this purpose, rinse with water, and refill with fresh fluid. Sodium omadine fungicide may be added to the fluid at the time it is prepared (diluted) or to the reservoir (sump) containing the fluid after it is put into use. If it is added to the reservoir, the fluid should be circulated after addition to ensure mixing. To inhibit the growth of fungi in aqueous metalworking, cutting, cooling and lubricating concentrates: Add an amount that will give up to 1250 ppm in the diluted fluid. The amount required in the concentrate will depend on the end use dilution. For example: If the desired level of Sodium omadine fungicide in the diluted fluid is 200 ppm, and the end use dilution of the fluid is 5%, then a 0.4% concentration of Sodium omadine fungicide is required in the concentrate (200 ppm/0.05 = 4,000 ppm or 0.4%). Heat Stability of Sodium omadine Sodium omadine fungicide is stable at 100°C for at least 120 hours. At 150°C, the assay of Sodium omadine fungicide decreases 29% during a 48-hour period. The heat of decomposition, as measured under nitrogen by differential scanning calorimetry, is 158 cal/g for Sodium omadine fungicide. pH Stability of Sodium omadine Sodium omadine fungicide can be used over the pH range from 4.5 to 11.0. Below pH 4.5, the sodium salt is in equilibrium with free pyrithione. Pyrithione is active microbiologically, but is very unstable in the presence of light or oxygen. Light Stability of Sodium omadine Sodium omadine fungicide will gradually degrade when exposed to light, depending on the nature of the formulation. Formulations containing Sodium omadine fungicide should be packaged in brown or opaque containers unless tests have shown that photodegradation is not a problem. Sodium omadine Fungicide is a highly active, broad-spectrum antimicrobial agent that, when used at recommended concentrations, can help to prevent and minimize problems associated with fungal contamination. Sodium omadine is the 40% aqueous sodium salt derivative of pyrithione. Sodium Omadine functions as a wet-state preservative against bacteria and fungus in latex paints. Sodium Omadine is a highly active, very effective water soluble sodium pyrithione. Offers pronounced growth-inhibiting activity against both yeasts and molds. Sodium Omadine possesses non-irritating and non-sensitizing properties. Chemical Properties Clear solution Uses For chemistry of 2-mercaptopyridine-N-oxide, see Aldrichimica Acta.1 Uses sodium pyrithione is a preservative that is not commonly used because of some level of toxicity. It is prohibited in Canada, and it is on the eu Annex II list of substances that must not form part of a cosmetic product composition. Uses Sodium omadine is a bactericide for use in cooling fluids and short-term in-can preservation of vinyl acetate latex, paints, and synthetic-fiber lubricants; preservative for cosmetic rinse-off products. Definition Apparently exists in equilibrium with the -SH form. Forms chelates with iron, manganese, zinc, etc. brand name Sodium Omadine (Olin). Safety Profile Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion, subcutaneous and parenteral routes. Used in preservation of cosmetics. When heated to decomposition it emits very toxic fumes of Na2O, NOx, and SOx. See also MERCAPTANS. Sodium omadine is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, Sodium omadine appears to interfere with membrane transport ultimately leading to a loss of metabolic control. Sodium omadine is the common name of an organosulfur compound with molecular formula C5H5NOS, chosen as an abbreviation of pyridinethione, and found in the Persian shallot. It exists as a pair of tautomers, the major form being the thione 1-hydroxy-2(1H)-pyridinethione and the minor form being the thiol 2-mercaptopyridine N-oxide; it crystallises in the thione form.[5] It is usually prepared from either 2-bromopyridine,[1] 2-chloropyridine, or 2-chloropyridine N-oxide,[8] and is commercially available as both the neutral compound and its sodium salt.[1] It is used to prepare zinc Sodium omadine, which is used primarily to treat dandruff and seborrhoeic dermatitis in medicated shampoos, though is also an anti-fouling agent in paints. Preparation The preparation of Sodium omadine was first reported in 1950[13] by Shaw[14] and was prepared by reaction of 2-chloropyridine N-oxide with sodium hydrosulfide followed by acidification,[8] or more recently with sodium sulfide.[15] 2-chloropyridine N-oxide itself can be prepared from 2-chloropyridine using peracetic acid.[16] Another approach involves treating the same starting N-oxide with thiourea to afford pyridyl-2-isothiouronium chloride N-oxide which undergoes base hydrolysis to Sodium omadine.[1][17] 2-Bromopyridine can be oxidised to its N-oxide using a suitable peracid (as per 2-chloropyridine), both approaches being analogous to that reported in Organic Syntheses for the oxidation of pyridine to its N-oxide. A substitution reaction using either sodium dithionite (Na2S2O4) or sodium sulfide with sodium hydroxide will allow the replacement of the bromo substituent with a thiol functional group. The alternative strategy is to form the mercaptan before introducing the N-oxide moiety. 2-Mercaptopyridine was originally synthesized in 1931 by heating 2-chloropyridine with calcium hydrosulfide,[6] an approach similar that first used to prepare Sodium omadine.[8] The analogous thiourea approach via a uronium salt was reported in 1958 and provides a more convenient route to 2-mercaptopyridine.[7] Oxidation to the N-oxide can then be undertaken. The disulfide diSodium omadine, 2,2'-dithiobis(pyridine-N-oxide) Sodium omadine is found as a natural product in the Allium stipitatum plant, an Asian species of onion, also known as the Persian shallot.[4] Its presence was detected using positive ion mass spectrometry using a DART ion source[19] and the disulfide diSodium omadine [de] (2,2'-disulfanediylbis(pyridine)-1,1'-dioxide) has been reported from the same species.[20] DiSodium omadine can be prepared in a laboratory by oxidation of Sodium omadine with chlorine in the presence of sodium hydroxide: 2 C5H4NOSH + Cl2 + 2 NaOH → ONC5H4–S–S–C5H4NO + 2 NaCl + 2 H2O DiSodium omadine is used as a fungicide and bactericide,[8] and has been reported to possess novel cytotoxic activity by inducing apoptosis.[21] Properties Tautomerisation of the sodium salt of Sodium omadine (thione form on the left, thiolate form on the right) Sodium omadine exists as a pair of prototropes, a form of tautomerism whereby the rapid interconversion of constitutional isomers involves the shift of a single proton, in this case between the sulfur and oxygen atoms (shown in the infobox above). Salts of the conjugate base of Sodium omadine can also be considered to exhibit tautomerism by notionally associating the sodium ion with whichever heteroatom bears the negative charge of the anion (as opposed to the formal charges associated with the N-oxide); however, considering the anion alone, this could also be described as an example of resonance. Sodium omadine is a weak acid with pKa values of −1.95 and +4.6 (thiol proton), but is a markedly stronger acid than either of its parent compounds (pyridine-N-oxide and pyridine-2-thiol), both of which have pKa > 8.[22] It is only slightly soluble in water (2.5 g L−1) but is soluble in many organic solvents (including benzene, chloroform, dichloromethane, dimethylformamide, dimethylsulfoxide, and ethyl acetate) and slight solubility in others (diethyl ether, ethanol, methyl tert-butyl ether, and tetrahydrofuran). Sodium omadine can be used as a source of hydroxyl radical in organic synthesis as it photochemically decomposes to HO• and (pyridin-2-yl)sulfanyl radical. Applications Structures of 1:2 complexes of zinc and the conjugate base of Sodium omadine Top: Structural formula of the monomer Bottom: Ball-and-stick model of the dimer The conjugate base of Sodium omadine (pyrithionate ion) is an anion containing two donor atoms, a sulfur atom and an oxygen atom each bearing a negative formal charge; the nitrogen atom remains formally positively charged. The thiolate anion can be formed by reaction with sodium carbonate, and zinc Sodium omadine is formed when zinc chloride is added.[10] The anion can act as either a monodentate or bidentate ligand and forms a 1:2 complex with a zinc(II) metal centre. Zinc Sodium omadine has been used since the 1930s though its preparation was not disclosed until a 1955 British patent[13] in which Sodium omadine was reacted directly with hydrated zinc sulfate in ethanol.[9] In its monomeric form, zinc Sodium omadine has two of the anions chelated to a zinc centre with a tetrahedral geometry. In the solid state, it forms a dimer in which each zinc centre adopts a trigonal bipyramidal geometry with two of the anions acting as bridging ligands coordinated through the oxygen atoms in the axial positions.[26] In solution, the dimers dissociate via scission of zinc-oxygen bonds to each bridging ligand. Further dissociation of the monomer into its constituents can occur and is undesirable as the complex is more potent in medical applications; for this reason, zinc carbonate can be added to formulations as it inhibits the monomer dissociation. Zinc Sodium omadine has a long history of use in medicated shampoos to treat dandruff and seborrhoeic dermatitis (dandruff can be considered a mild form of seborrheic dermatitis). It exhibits both antifungal and antimicrobial properties, inhibiting the Malassezia yeasts which promote these scalp conditions. The mechanisms by which this work are the subject of ongoing study. It can be used as an antibacterial agent against Staphylococcus and Streptococcus infections for conditions such as athlete's foot, eczema, psoriasis, and ringworm. It is known to be cytotoxic against Pityrosporum ovale, especially in combination with ketoconazole, which is the preferred formulation for seborrheic dermatitis.[11] Sodium omadine itself inhibits membrane transport processes in fungi. Paints used in external environments sometimes include zinc Sodium omadine as a preventive against algae and mildew. Sodium omadine zinc is an antibacterial and antifungal agent developed by scientists in the 1930's. Since then it has been used to treat seborrheic dermatitis of the scalp and other skin conditions such as eczema, athlete's foot, and vitiligo, as well as psoriasis. Because of its antifungal properties, it is commonly found in dandruff shampoo. Products containing Sodium omadine zinc are available today with and without prescription, and it is the main ingredient in many over-the-counter creams, lotions, soaps, and shampoos. It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera. Sodium omadine zinc`s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo. Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. Stability: At room temperature in the dark, Sodium omadine is stable in the pH range 4.5 to 9.5. At 100°C it is stable for at least 120 hours, at 150°C 29 % of the substance has decomposed within 48 hours. In the light or in contact with weak oxidizing agents Sodium omadine is converted to the disulfide, 2,2-pyridyl-N-oxide disulfide. With stronger oxidizing agents or in alkaline solution (pH > 9.5) the substance is converted via a number of intermediates to the sulfonic acid; the reaction with reducing agents yields thiopyridine (Olin Corporation 1989f). Independent of the exposure route, Sodium omadine is of low toxicity. The typical symptom of intoxication in rats, mice and rabbits given single or multiple doses of the substance is reversible paralysis of the rear extremities. This effect is not seen in monkeys or dogs. In both these species effects on the pupillary reflex and photophobia were observed. Irreversible eye damage, however, has been seen only in species which have a tapetum lucidum, for example, the dog. Sodium omadine is readily absorbed from the gastrointestinal tract and through the intact skin. The substance is excreted rapidly in the form of urinary metabolites. Applied to rabbits, the substance causes slight irritation of the skin and eyes. Brief contact with aqueous solutions containing less than 1 % Sodium omadine produced no effects in animals or man; sensitization could not be demonstrated. Reproductive toxicity is not observed, either after dermal application to rats or rabbits or after oral administration to rats. Embryotoxicity develops in rats but not in rabbits after maternally toxic doses of Sodium omadine. Genotoxic effects of Sodium omadine could not be demonstrated in the Salmonella mutagenicity test, in the HPRT (hypoxanthine guanine phosphoribosyl transferase) test or in the test for DNA repair in rat hepatocytes. However, because the substance is cytotoxic, only low concentrations could be tested. Negative results were also obtained in vivo in the micronucleus test. Sodium omadine is not carcinogenic either after dermal application to mice or after oral administration to rats. There are no reports of toxic effects of single exposures of persons to Sodium omadine. Reproductive toxicity, genotoxicity and carcinogenicity of Sodium omadine in man have not been described. Sodium omadine zinc, or zinc Sodium omadine or zinc pyridinethione, is a coordination complex consisted of Sodium omadine ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, Sodium omadine zinc is used to treat dandruff and seborrheic dermatitis. Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3. Sodium omadine zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos. It mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth 1. Due to low solubility, Sodium omadine zinc released from the topical formulations is deposited and retained relatively well onto the target skin surfaces 2. Other uses of Sodium omadine zinc include additive in antifouling outdoor paints and algaecide. While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Sodium omadine zinc has been reported for decades. It is not shown to have any significant estrogenic activity according to the in vivo and in vitro assays 4. Photodegradation in water A study of the photolysis rate of sodium omadine has been carried out. In a GLP study conducted according to US guideline US FDA Technical Assistance Document, Guideline 3.10 Photodegradation. 1987.) (5.1.3.001, EZPTF 7011-121) at a concentration of 10 mg/L, DT50for photolysis were determined to be <10 minutes at pH 5 and 7 and <15 minutes at pH 9. Degradants were not identified in this study. A further study of the aqueous photolysis rate of Sodium omadine has also been conducted (refer to Table 5.1.2). Study (5.1.3.003, EZPTF 7011-123) was conducted to determine the influence of concentration on photolysis rates. Photolysis was done in deionized water with zinc Sodium omadine concentrations of 0.1-1 μg/L, which are much closer to predicted environmental concentrations than those of the other two studies. Exposure to natural sunlight (42° N latitude) was done in quartz tubes at noon during the months of July through October. ZnPT was shown to have considerable absorptivity in the range of 290-400 nm, where photoactive solar radiation is available and photolysis in natural sunlight was very rapid. Measured photolysis half-lives ranged from 1.1 to 1.4 minutes in deionized water. Simultaneous exposure of the actinometer (o‑nitrobenzaldehyde) solutions allowed the calculation of photolysis disappearance quantum yields. Reproducibility at the very low concentrations used in this study required that several exposure experiments be run for each test compound and the results averaged. The quantum yield for ZnPT at 3.15 x 10-9M and 3.15 x 10-10M was 0.17 ± 0.06 (n = 4). This study also demonstrated that three metallic complexes of Sodium omadine (Zinc, Copper and Sodium) all exhibited the same photolysis rate at environmentally relevant concentrations. Photodegradation in air This point is regarded not to be relevant because: - the vapour pressure of NaPT is very low, resulting in negligible exposure to the atmosphere. - the calculation according to the Atkinson calculation method (5.1.1.001, ESPTF 7031-001) indicates a short half-life (53.8 hours) of sodium Sodium omadine in the atmosphere. Summary of degradation - Sodium Sodium omadine is hydrolytically stable. - Sodium Sodium omadine passes the ready biodegradability test according to OECD 301B and biodegradation is rapid in soil, water-sediment, and STP. The degradation profile is well identified passing through several transient degradants to a final somewhat persistent degradant 2‑pyridine sulphonic acid (PSA). - Photolysis is extremely rapid—again leading to the final somewhat persistent degradant 2‑pyridine sulphonic acid (PSA). - The final degradant, PSA, passes the ready biodegradability test according to OECD 301B. Sodium omadine is a fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, Sodium omadine appears to interfere with membrane transport ultimately leading to a loss of metabolic control. Absorption Following oral ingestion, only the Sodium omadine moiety is absorbed. Less than 1% of administered zinc Sodium omadine is absorbed from the skin [L1758]. Radioabeled Zn Sodium omadine administered to rats, rabbits and monkeys, either orally or via intraperitoneal injection were absorbed into circulatin to extent of 80-90% [L1758].Inhibition of fungal growth by Sodium omadine zinc is linked to increased copper uptake and cellular levels of copper, which is demonstrated by decreased CTR1-lacZ expression and slightly increased CUP1-lacZ expression in affected microorganisms [A32162]. The coordination complex of Sodium omadine zinc dissociates, and Sodium omadine ligand forms a CuPT complex from available extracellular copper in the target organism. Sodium omadine acts as an ionophore, interacting nonspecifically with the plasma membrane to shuttle copper into the cell, and facilitates copper transport across intracellular membranes [A32162]. Copper may be shuttled into the mitochondria. Copper inactivates iron-sulfur (Fe-S) cluster-containing proteins via a mechanism similar to that described for copper-induced growth inhibition in bacteria [A32162]. Decreased activity of Fe-S proteins leads to inhibition of fungal metabolism and fungal growth. Sodium omadine zinc has been shown to slightly increase the levels of zinc [A32162]. Sodium omadine (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis. Structure of the compound The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. In the crystalline state, Sodium omadine exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.[3] In solution, however, the dimers dissociate via scission of one Zn-O bond. This compound was first described in the 1930s. Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide. Uses Medical Sodium omadine can be used to treat dandruff and seborrhoeic dermatitis.[medical citation needed] It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.[medical citation needed] Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor,[5] and vitiligo. In paint Due to its low solubility in water (8 ppm at neutral pH), Sodium omadine is suitable for use in outdoor paints and other products that provide protection against mildew and algae. It is an effective algaecide. It is chemically incompatible with paints relying on metal carboxylate curing agents. When used in latex paints with water containing high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed. Its decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight. In sponges Sodium omadine is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.[6] In clothing A process to apply Sodium omadine to cotton with washable results was patented in the United States in 1984.[7] Sodium omadine is now used to prevent microbe growth in polyester.[8] Textiles with applied Sodium omadine protect against odor-causing microorganisms. Export of antimicrobial textiles reached US$497.4 million in 2015. Mechanism of action Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. Health effects Sodium omadine is approved for over-the-counter topical use in the United States as a tr

Sodium Omadine 40% Fungicide is a highly active, broad-spectrum antimicrobial agent that, when used at recommended concentrations, can help to prevent and minimize problems associated with fungal contamination.
Sodium Omadine 40% is the 40% aqueous sodium salt derivative of pyrithione.
Sodium Omadine 40% is incorporated into certain paints and coatings to provide antimicrobial properties, helping to prevent the growth of bacteria and fungi on surfaces.

CAS Number: 3811-73-2
Molecular Formula: C5H6NNaOS
Molecular Weight: 151.16
EINECS Number: 223-296-5

Sodium Omadine, 3811-73-2, Sodium pyrithione, Sodium (2-pyridylthio)-N-oxide, Pyrithione sodium salt, Omadine sodium, PYRITHIONE SODIUM, 2-Pyridinethiol-1-oxide sodium salt, sodium (1-oxidopyridin-1-ium-2-yl)sulfanide, MFCD01941547, 2-Mercaptopyridine 1-oxide sodium salt, DTXSID3042390, 2-Mercaptopyridinen-oxide sodium salt, 2-Mercaptopyridine N-oxide (sodium), Tomicide s, 1-Hydroxy-2-pyridinethione sodium salt, 6L3991491R, Topcide 280, 2-Pyridinethiol, 1-oxide, sodium salt (1:1), 2-Pyridinethiol 1-Oxide Sodium Salt, Sodium 2-sulfidopyridine 1-oxide, NSC-4483, Sodium omadine (VAN), AL-02725, Sodium pyrithione (VAN), 1-Hydroxy-2(1H)-pyridinethione, sodium salt, 2(1H)-Pyridinethione, 1-hydroxy-, sodium salt, 2-Mercaptopyridine n-oxide sodium, Prestwick_78, NSC 4483, EINECS 223-296-5, Sodium, (2-pyridylthio)-, N-oxide, Sodium, (2-pyridinylthio)-, N-oxide, 2-Pyridinethiol, N-oxide, sodium salt, (1-Hydroxy-2-pyridinethione), sodium salt, AI3-22596, 2-Mercaptopyridine N-oxide sodium salt anhydrous, SCHEMBL3101261, CHEMBL2364542, DTXCID1022390, SODIUM PYRITHIONE [INCI], AMY3577, WNGMMIYXPIAYOB-UHFFFAOYSA-M, UNII-6L3991491R, N-Hydroxypyridinethione Sodium Salt, PYRITHIONE SODIUM [WHO-DD], STR00395, Tox21_300128, AKOS000121187, 2-Mercaptopyridine-1-oxide sodium salt, AC-1079, HY-125785A, Pyridine-2-thiol 1-oxide, sodium salt, NCGC00254107-01, SY061676, CAS-3811-73-2, CS-0129647, M0632, M2841, 2-Mercaptopyridine N-oxide sodium salt, 95%, 2-Mercaptopyridine N-oxide sodium salt, 98%, 2-PYRIDINETHIOL-1-OXIDE, SODIUM SALT, EN300-18847, 2-Mercaptopyridine-N-oxide sodium salt hydrate, EC 223-296-5, 2-Mercaptopyridine N-oxide sodium salt, >=96%, (1-Hydroxy-2-pyridinethione), sodium salt, tech., W-106499, Q27265081, Z90667629, 2-Mercaptopyridine N-oxide sodium salt, >=96.0% (NT), SODIUM SALT OF 1-HYDROXY 2(1H)-PYRIDINE, THIONE,Mercaptopyridine n-oxide sodium,N-Hydroxypyridinethione Sodium Salt,EBD41219,STR00395,Tox21_300128,AKOS000121187,sodium1-, oxidopyridin-1-ium-2-thiolate,2- ercaptopyridine-1-oxide sodium salt,AC-1079,HY-125785A,Pyridine-2-thiol 1-oxide, sodium salt, NCGC00254107-01, CAS-3811-73-2, CS-0129647,M0632,M2841,Sodium, (2 pyridylthio)-, N-oxide (7CI),2-Mercaptopyridine N-oxide sodium salt, 95%,EC 223-296-5,2-Mercaptopyridine N-oxide sodium salt, >=96%,(1-Hydroxy-2-pyridinethione), sodium salt, tech.,2-Mercaptopyridine N-oxide sodium salt, anhydrous,W-106499,Q27265081,2-Mercaptopyridine N-oxide sodium salt, >=96.0% (NT),Sodium pyridine-2-thiolate N-oxide, 40% aqueous solution,2-Mercaptopyridine N-oxide sodium salt solution, ~40% in H2O, very deep brown,Sodium2-pyridinethiol-1-oxide, 2-Mercaptopyridine-N-oxide sodium salt,,2-Pyridinethiol-1-oxide sodium salt, N-Hydroxy-2-pyridinethione sodium salt,Omadine sodium, Omadine sodium 40%, pyrithione sodium, 2-Pyridinethiol, 1-Hydroxy-2-pyridinethione sodium salt, 2- Mercaptopyridine-1-oxide sodium salt, 2-Pyridinethiol-1-oxide sodium salt, Pyrithione sodium salt, 2-mercaptopyridine-N-oxide, 1- hydroxypyridine-2-thione, 2-pyridinethiol-1-oxide (CAS No. 1121-31-9), 1-hydroxy-2(1H)-pyridinethione (CAS No. 1121-30-8), NaPT, Sodi, UT900000, SODIUM OMADINE, thione(reagent), Sodium pyrithion, SODIUM PYRITHIONE, PYRITHIONE SODIUM, PYRITHIONE SODIUM SALT, Sodium pyrithione(NaPT), Sodium (2-pyridylthio)-N-oxide (3811-73-2), 15922-78-8: Pyrithione sodium, 1-Hydroxy-2(1H)-pyridinethionato sodium, 1-Hydroxy-2(1H)-pyridinethione, sodium salt, AL02725, Omacide 24, Omadine sodium, SQ 3277, Sel de sodium de 1-hydroxy-2 (1H)- pyridinethione [French], Sodium 1-hydroxypyridine-2-thione

Sodium Omadine 40% fungicide is registered with the United States Environmental Protection Agency under the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA), for use in metalworking, cutting, cooling and lubricating concentrates and enduse fluids.
Sodium Omadine 40% helps control the growth of the yeast Malassezia, which is associated with dandruff.
Sodium Omadine 40% is used in various industrial applications where antimicrobial properties are required.

This includes its use in formulations for coatings, paints, and other materials.
In some formulations, Sodium Omadine 40% can serve as a preservative, helping to prevent the growth of microorganisms in products like paints and adhesives.
Sodium Omadine 40% is generally compatible with a range of formulations, but its effectiveness and stability can depend on the specific product and conditions of use.

Products containing sodium omadine are subject to regulatory oversight, and their use and concentration may be governed by local regulations and guidelines.
Sodium Omadine 40% Fungicide by Arxada is a sodium pyrithione.
Sodium Omadine 40% Fungicide provides good short-term protection against bacteria and fungus.

In the United States Sodium Omadine 40% is a violation of federal law to use an antimicrobial agent in an application for which it does not have EPA registration.
Sodium Omadine 40% is a fungicide, 40% active content, formaldehyde free, pH stable aqueous solution designed for concentrates and tankside use.
Avoid use in cast iron grinding applications.

Sodium Omadine 40% is a broad spectrum antifungal agent and is effective against many fungi (yeast and mold) commonly found in metalworking fluid systems and an excellent choice for use as a tankside additive.
Sodium Omadine 40% is a chemical compound that is commonly used as a broad-spectrum antimicrobial agent.
The active ingredient in sodium omadine is 2-pyridinethiol-1-oxide, commonly known as pyrithione.

Sodium Omadine 40%'s are effective against a wide range of microorganisms, including bacteria and fungi.
Sodium Omadine 40% refers to a solution in which the active ingredient, sodium pyrithione, is present at a concentration of 40%.
This solution is often used in various applications, such as in the formulation of antimicrobial products, including shampoos, soaps, and industrial disinfectants.

Sodium omadine 40% is known for its antimicrobial properties.
Sodium Omadine 40% can inhibit the growth of bacteria and fungi, making it effective in products designed for hygiene and disinfection.
Sodium Omadine 40%, particularly in lower concentrations, is commonly used as an active ingredient in dandruff shampoos.

In addition to dandruff shampoos, Sodium Omadine 40% may be included in certain skin care products, such as soaps and lotions, to impart antimicrobial effects.
Sodium Omadine 40% can be used in textile treatments to provide antimicrobial properties to fabrics, reducing the growth of odor-causing bacteria and fungi.
Some personal care products, including body washes and hand sanitizers, may contain sodium omadine as an antimicrobial agent.

Sodium Omadine 40% has been explored for its potential use in water treatment applications to control the growth of microorganisms in water systems.
Certain plastic and polymer products may incorporate Sodium Omadine 40% to provide antimicrobial properties, particularly in applications where microbial growth could be a concern.
Sodium Omadine 40% can be used in the formulation of adhesives and sealants to prevent the growth of microorganisms, contributing to product stability.

In the leather industry, Sodium Omadine 40% may be used in treatments to provide antimicrobial effects, helping to preserve and protect leather products.
Sodium Omadine 40% has been explored for its potential use in wood preservation treatments, where it could contribute to preventing decay caused by fungi and bacteria.
Sodium Omadine 40% may be incorporated into metalworking fluids to control the growth of microorganisms, maintaining the quality of the fluids.

In certain applications, Sodium Omadine 40% is used to protect copper and copper alloys from corrosion caused by microorganisms.
Sodium Omadine 40% can be part of formulations for disinfectants and sanitizers, contributing to their antimicrobial efficacy.
In veterinary products, Sodium Omadine 40% may be used in certain formulations, such as shampoos for pets, to address skin conditions and control microbial growth.

Sodium Omadine 40% has been studied for its potential use in cooling tower water treatment to control microbiological fouling.
Sodium Omadine 40% may find applications in the oil and gas industry for controlling microbial growth in various processes.
Sodium Omadine 40% is widely used as a biocide, meaning it has the ability to kill or inhibit the growth of various microorganisms, including bacteria, fungi, and algae.

In the marine industry, Sodium Omadine 40% is employed in antifouling coatings to prevent the growth of marine organisms on ship hulls, reducing drag and fuel consumption.
Sodium Omadine 40% may be used in the paper and pulp industry to control microbial growth in various stages of paper production.
Sodium Omadine 40% is utilized in cooling water treatment to prevent the formation of biofilms, algae, and other microorganisms that can impact the efficiency of cooling systems.

Sodium Omadine 40% has been studied for its potential use in reservoir preservation, particularly in preventing microbial-related issues in water reservoirs.
In enhanced oil recovery processes, Sodium Omadine 40% may be considered to control microbial growth and maintain fluid quality.
Sodium Omadine 40% may be employed in petrochemical processes to inhibit microbial fouling and degradation of equipment.

Sodium Omadine 40% may find applications in agriculture, including the preservation of agricultural products and the control of microbial contaminants in farm settings.
Sodium Omadine 40% can be added to metal cutting fluids to prevent microbial contamination and maintain the stability of the fluids during machining processes.
In the oil and gas sector, Sodium Omadine 40% may be employed in drilling fluids and completion fluids to control microbial growth in oilfield operations.

Sodium Omadine 40% may be used in certain biomedical and healthcare products, such as wound care formulations, where antimicrobial properties are desired.
Sodium Omadine 40% can be used in treatments for footwear and textiles to impart antimicrobial properties, reducing odor and microbial growth.
Sodium Omadine 40% is applied in wood coatings to protect against decay caused by fungi and bacteria, particularly in outdoor or humid environments.

In the construction industry, Sodium Omadine 40% may be incorporated into concrete additives to prevent the growth of microorganisms on surfaces.
Sodium Omadine 40% is effective in controlling mold and mildew growth in various applications, such as in building materials and household products.
Sodium Omadine 40% can be used in water-based systems, such as paints and adhesives, to prevent microbial contamination and extend the shelf life of these product.

Sodium Omadine 40% finds applications in the metalworking industry for preserving metalworking fluids and preventing microbial degradation.
Sodium Omadine 40% may be utilized in the polymer industry to control microbial contamination in polymer formulations.
Sodium Omadine 40% possesses high water solubility, high activity and non-irritating & non-sensitizing properties.

Melting point: -25 °C
Boiling point: 109 °C
Density: 1.22
vapor pressure: 0-0Pa at 25℃
refractive index:1.4825
storage temp.. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: H2O: 0.1 M at 20 °C, clear, faintly yellow
form: Solution
color: very deep brown
Water: Solubility: 54.7 g/100 mL
Sensitive: Hygroscopic
λmax: 334nm(H2O)(lit.)
Merck: 14,7994
BRN: 4026050
InChIKey: WNGMMIYXPIAYOB-UHFFFAOYSA-M
LogP: -2.38 at 20℃ and pH7

Sodium Omadine 40% is used in waterborne coatings for wood, metal, and other substrates to inhibit the growth of mold, mildew, and other microorganisms.
Sodium Omadine 40% is used in some paints labeled as anti-mold or anti-mildew paints for interior and exterior applications.
Sodium Omadine 40% may be incorporated into polyurethane foams to prevent the growth of microorganisms, making it suitable for various applications, including mattresses and cushions.

Sodium Omadine 40% can be used in biomedical coatings, such as those used in medical devices, to provide antimicrobial protection.
Sodium Omadine 40% may be used in disinfectant wipes to provide antimicrobial efficacy for surface cleaning and disinfection.
In the formulation of latex binders, Sodium Omadine 40% may be added to provide protection against microbial degradation.

Sodium Omadine 40% can be used in treatments for carpets and textiles to prevent the growth of odor-causing bacteria and fungi.
Sodium Omadine 40% may find applications in air purification systems to inhibit microbial growth on filters and surfaces within the system.
Sodium Omadine 40% is sometimes included in household cleaning products, such as multi-surface cleaners, to provide antimicrobial benefits.

Sodium Omadine 40% can be included in air fresheners and deodorizers to provide antimicrobial benefits, particularly in formulations designed to eliminate odors caused by microbial activity.
Sodium Omadine 40% is employed in humidifier treatments to prevent microbial growth in the water reservoir of humidification systems.
In aquaculture settings, Sodium Omadine 40% may be used to control microbial contamination in water systems and protect aquatic organisms.

Sodium Omadine 40% can be applied to construction materials, such as wood and metal, to prevent microbial decay and degradation.
Sodium Omadine 40% may be used in water-based adhesive formulations to prevent microbial contamination and maintain adhesive performance.
Sodium Omadine 40% can be incorporated as an additive in paper coatings to provide antimicrobial protection and enhance the longevity of paper products.

Sodium Omadine 40% is employed in some filtration systems to prevent microbial growth on filter media, ensuring the efficiency of the filtration process.
In the construction industry, Sodium Omadine 40% may be used in concrete sealers to protect against microbial deterioration of concrete surfaces.

Sodium Omadine 40% is sometimes used as an active ingredient in antimicrobial sprays for various surfaces, providing a protective barrier against microbial contamination.
Sodium Omadine 40% can be utilized in septic tank treatments to control the growth of bacteria in the tank and prevent odor issues.

Uses:
Sodium Omadine 40% is used in the preservation of various industrial fluids, such as metalworking fluids, to prevent microbial degradation.
Sodium Omadine 40% can be added to concrete formulations or coatings to prevent microbial deterioration of concrete surfaces.
Sodium Omadine 40% may find applications in the oil and gas industry, particularly in drilling fluids and completion fluids, to control microbial growth.

Sodium Omadine 40% is used in some household cleaning products, contributing to their antimicrobial efficacy.
Sodium Omadine 40% may be used in cosmetic formulations for its antimicrobial benefits, especially in products designed for sensitive skin.

Sodium Omadine 40% can be applied to footwear to inhibit the growth of odor-causing bacteria and fungi.
Sodium Omadine 40% may be included in air fresheners and deodorizers to provide antimicrobial benefits.
In veterinary applications, Sodium Omadine 40% may be used in certain formulations such as shampoos for pets to address skin conditions.

Sodium Omadine 40% is used in treatments for humidifiers to prevent microbial growth in the water reservoir.
Sodium Omadine 40% may find applications in air purification systems to inhibit microbial growth on filters and surfaces within the system.
Sodium Omadine 40% can be used in treatments for carpets and textiles to prevent the growth of odor-causing bacteria and fungi.

In aquaculture settings, Sodium Omadine 40% may be used to control microbial contamination in water systems and protect aquatic organisms.
Sodium Omadine 40% can be applied to construction materials, such as wood and metal, to prevent microbial decay and degradation.
Sodium Omadine 40% is used in some paints labeled as anti-mold or anti-mildew paints for interior and exterior applications.

Sodium Omadine 40% may be incorporated into polyurethane foams to prevent the growth of microorganisms, making it suitable for various applications, including mattresses and cushions.
Sodium Omadine 40% can be used in biomedical coatings, such as those used in medical devices, to provide antimicrobial protection.
Sodium Omadine 40% may be used in disinfectant wipes to provide antimicrobial efficacy for surface cleaning and disinfection.

In the formulation of latex binders, Sodium Omadine 40% may be added to provide protection against microbial degradation.
Sodium Omadine 40% can be incorporated into car wash products to prevent microbial growth and maintain the cleanliness of vehicle surfaces.
Sodium Omadine 40% may be used in coolant systems for engines and industrial machinery to prevent microbial contamination and maintain system efficiency.

In the transportation of fluids through pipelines, Sodium Omadine 40% may be used to prevent microbial fouling and degradation of the pipeline.
Sodium Omadine 40% can be included in household disinfectants to enhance their antimicrobial properties for cleaning and disinfecting surfaces.
Sodium Omadine 40% may find applications in agriculture as an ingredient in certain sprays or formulations designed to control microbial growth in crop protection.

In the production of molded plastics, Sodium Omadine 40% may be used to provide antimicrobial protection to the final products.
Sodium Omadine 40% may be used in dehumidifiers to inhibit microbial growth in water reservoirs and prevent the release of airborne contaminants.
Sodium Omadine 40% can be used in metal surface treatments to protect against microbial corrosion and degradation.

Sodium Omadine 40% may be considered as an additive in fuels to inhibit microbial growth and prevent fuel system issues.
Sodium Omadine 40% may be used in coatings for fiber optic cables to prevent microbial degradation and ensure the reliability of communication systems.
Sodium Omadine 40% may be included in various hygiene products, such as hand sanitizers and wipes, for its antimicrobial benefits.

Sodium Omadine 40% may be added to adhesives and sealants to prevent microbial contamination, ensuring the stability of these products.
Sodium Omadine 40% can be used in the paper and pulp industry to control microbial growth during various stages of production.
Sodium Omadine 40% is a key ingredient in many dandruff shampoos.

Sodium Omadine 40% helps control the growth of the yeast Malassezia, which is associated with dandruff.
Sodium Omadine 40% is used in various personal care products such as soaps, body washes, and lotions for its antimicrobial properties.
Sodium Omadine 40% may be incorporated into textiles and fabrics to impart antimicrobial properties, reducing the growth of odor-causing bacteria.

Sodium Omadine 40% is used in paints and coatings to prevent the growth of mold and mildew on surfaces, particularly in humid environments.
Sodium Omadine 40% is applied in wood treatments to protect against decay caused by fungi and bacteria, extending the life of wood products.
In the marine industry, Sodium Omadine 40% is used in anti-fouling coatings to prevent the attachment and growth of marine organisms on ship hulls.

Sodium Omadine 40% can be used in water treatment applications to control the growth of bacteria and algae in water systems.
Sodium Omadine 40% is employed in cooling tower water treatment to inhibit the growth of microorganisms, preventing biofilm formation and maintaining system efficiency.

Safety profile:
Sodium Omadine 40% is not meant to be ingested, and accidental ingestion may lead to nausea, vomiting, abdominal pain, and other gastrointestinal issues.
Some individuals may be sensitive or allergic to Sodium Omadine 40%.
Allergic reactions can manifest as skin irritation, redness, itching, or other symptoms.

Individuals with known sensitivities should take precautions and seek medical advice if needed.
Inhalation of Sodium Omadine 40% dust or vapors may irritate the respiratory system.
Sodium Omadine 40% is important to handle the substance in well-ventilated areas and to use appropriate personal protective equipment, such as respiratory protection, if necessary.

Sodium Omadine 40% can cause irritation to the skin and eyes. Prolonged or repeated contact with the skin may lead to dermatitis or other skin conditions.
In case of contact with the eyes, it can cause irritation and redness.
Ingesting Sodium Omadine 40% can be harmful.

SODIUM OXYMETHYLENE SULFOXYLATE N° CAS : 149-44-0 Nom INCI : SODIUM OXYMETHYLENE SULFOXYLATE Nom chimique : Sodium hydroxymethanesulphinate N° EINECS/ELINCS : 205-739-4 Ses fonctions (INCI) Agent réducteur : Modifie la nature chimique d'une autre substance en ajoutant de l'hydrogène ou en éliminant l'oxygène

Sodium o-phenylphenate (SOPP) is an organic molecular entity.
Sodium o-phenylphenate (SOPP) is a light brown or beige solid.
Sodium o-phenylphenate (SOPP) is soluble in water, yielding solutions with pHs of 12.0-13.5.


CAS Number: 132-27-4
EC Number: 205-055-6
MDL Number:MFCD00134130
E number: E232 (preservatives)
Molecular Formula: C12H10O.Na



Sodium 2-Biphenylate, (2-biphenylyloxy)sodium, bactrol, D.C.S., dorvicide a, Dowicide, dowicide a, dowizid, mil-du-rid, natriphene, OPP-NA, orphenol, preventolon, Preventol ON extra, [1,1'-Biphenyl]-2-ol, sodium salt, 2-Biphenylol, Sodium Salt, Sodium ortho-phenylphenate, 2-Phenylphenol Sodium Salt, sodium o-phenylphenolate, o-phenylphenol, sodium deriv., Sodium o-phenylphenoxide, Biphenylol, sodium salt, Hydroxydiphenyl, sodium salt, Phenylphenol, sodium salt, SOPP, stopmold b, topane, O-Phenyl phenol sodium salt tetrahyate, sodium biphenyl-2-olate, sodium biphenyl-2-olate hydrate (1:1:4), biphenyl-2-olate, [1,1'-biphenyl]-2-ol, sodium salt (1:1), Ortho-phenylphenol,sodium salt, 2-hydroxybiphenyl sodium salt tetrahydrate, o-Phenyl phenol sodium salt, (1,1'-Biphenyl)-2-ol, sodium salt, 2-Biphenylol sodium salt, 2-Hydroxybiphenyl sodium salt, 2-Hydroxydiphenyl sodium, 2-Hydroxydiphenyl, sodium salt,
2-Phenylphenol sodium salt, Bactrol, D.C.S., Dowicide, Dowicide A, Dowicide A & A flakes, Dowicide A Flakes, Dowizid A, Mil-Du-Rid, Mystox WFA, Natriphene,
OPP-sodium, Orphenol, Phenol, o-phenyl-, sodium deriv., Phenylphenol, sodium salt, Preventol ON & ON Extra, Preventol ON extra, Preventol-ON,
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Sodium ortho-phenylphenate, Stopmold B, Sodium 2-biphenylolate, Mystox WFA, Preventol ON extra, Dowicide A, Sodium 2-phenylphenate, o-Phenylphenate, sodium, Sodium o-phenylphenolate, Sodium o-phenylphenoxide, Sodium 2-phenylphenoxide, 2-Biphenylol sodium salt, 2-Biphenylol, sodium salt, Bactrol, Dowicide,
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Preventol ON & ON Extra, Sodium 2-biphenylate tetrahydrate, Sodium, (2-biphenylyloxy)-, CCRIS 693, NSC-1547, 2-Hydroxydiphenyl, sodium salt,
Sodium-o-phenylphenol, Sodium-o-phenylphenate, NSC 1547, Sodium 2-Phenylphenolate, EINECS 205-055-6, UNII-KFV9K7N7UI, EPA Pesticide Chemical Code 064104, AI3-09076, Phenol, o-phenyl-, sodium deriv., Sodium o-phenylphenate tetrahydrate, sodium phenylphenate, sodium;2-phenylphenolate, Sodium 2-Hydroxybiphenyl, MICROBAN P 2, potassium o-phenyl-phenate, 2-BIPHENYLOL, SODIUM SALT, TETRAHYDRATE, SCHEMBL73034, Ortho-phenylphenol, sodium salt, DTXSID2021153, CHEBI:82371, KSQXVLVXUFHGJQ-UHFFFAOYSA-M, Sodium[1,1'-biphenyl]-2-olate, MFCD00002209, SODIUM O-PHENYLPHENATE [INCI], AKOS006228608, AKOS015913820, O-PHENYLPHENOL SODIUM SALT [MI], SODIUM ORTHO-PHENYLPHENATE [IARC], AS-81717, SY030153, Sodium [1,1'-biphenyl]-2-olate(Flakes), CS-0156415, FT-0743610, P0202, (1,1'-Biphenyl)-2-ol, sodium salt (1:1), C19298, F71217, (1,1'-Biphenyl)-2-ol, sodium salt, tetrahydrate, A852225, J-524265, Q6581446, Sodium (1,1'-biphenyl)-2-olate, sodium o-phenylphenate, sodium ophenylphenolate, 2-Hydroxybiphenyl sodium salt, Sodium ortho-phenylphenate, 2-Phenylphenol sodium salt, sodium o-phenylphenolate, Sodium o-phenylphenate, Sodium o-phenylphenolate, Sodium (1,1'-biphenyl)-2-olate, Sodium 2-Biphenylate, (2-biphenylyloxy)sodium,
bactrol, D.C.S., dorvicide a, Dowicide, dowicide a, dowizid, mil-du-rid, natriphene, OPP-NA, orphenol, preventolon, Preventol ON extra, [1,1'-Biphenyl]-2-ol, sodium salt, 2-Biphenylol, Sodium Salt, Sodium ortho-phenylphenate, 2-Phenylphenol Sodium Salt, sodium o-phenylphenolate, o-phenylphenol, sodium deriv.,
Sodium o-phenylphenoxide, Biphenylol, sodium salt, Hydroxydiphenyl, sodium salt, Phenylphenol, sodium salt, SOPP, stopmold b, topane, O-Phenyl phenol sodium salt tetrahyate, sodium biphenyl-2-olate, sodium biphenyl-2-olate hydrate (1:1:4), biphenyl-2-olate, [1,1'-biphenyl]-2-ol, sodium salt (1:1),
Ortho-phenylphenol,sodium salt, 2-hydroxybiphenyl sodium salt tetrahydrate, (1,1’-biphenyl)-2-ol,sodiumsalt, (2-biphenylyloxy)-sodium, [1,1’-Biphenyl]-2-ol,sodiumsalt, 2-biphenylol,sodiumsalt, 2-hydroxydiphenyl,sodiumsalt, 2-hydroxydiphenylsodium, bactrol, d.c.s. Sodium 2-biphenylate, Sodium o-phenylphenate, (1,1-Biphenyl)-2-ol, sodium salt, 2-Biphenylol, sodium salt, 2-Hydroxybiphenyl sodium salt, 2-Hydroxydiphenyl sodium salt, 2-Phenylphenol sodium salt o-Phenylphenol sodium salt, Sodium 2-biphenylolate, Sodium biphenyl-2-yl oxide, Sodium 2-hydroxydiphenyl, Sodium o-phenylphenol, Sodium 2-phenylphenolate, Sodium o-phenylphenolate, Sodium o-phenylphenoxide, SOPP, SODIUMBIPHENYL2-OLATE, SODIUM2-PHENYLPHENOL, SODIUMORTHO-PHENYLPHENOXIDE, SODIUM2-PHENYLPHENOXIDE, SODIUM2-BIPHENYLOL, Natrium-2-biphenylat, 2-PHENYLPHENOL, SODIUM SALT TETRAHYDRATE, SYNTHESIS GRADE,



Sodium o-phenylphenate (SOPP) is a beige flaky solid.
pH of saturated solution of Sodium o-phenylphenate (SOPP) in water: 12.0-13.5.
Sodium o-phenylphenate (SOPP) is an organic molecular entity.


Sodium o-phenylphenate (SOPP) is an organic molecular entity.
Sodium o-phenylphenate (SOPP) is a light brown or beige solid.
Sodium o-phenylphenate (SOPP) is soluble in water, yielding solutions with pHs of 12.0-13.5.


Sodium o-phenylphenate (SOPP) is the sodium salt of biphenyl-2-carboxylic acid.
Sodium o-phenylphenate (SOPP) is an antimicrobial agent that has been shown to exert its effect by inhibiting the growth of bacteria, including Aerobacter aerogenes.


Sodium o-phenylphenate (SOPP) is beige flaky solid.
pH of saturated solution of Sodium o-phenylphenate (SOPP) in water is 12.0-13.5.
Sodium o-phenylphenate (SOPP) is a white powder of flakes; absorbs carbon dioxide and releases free ophenylphenol which slowly sublimes when exposed to air.


Sodium o-phenylphenate (SOPP) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.
Sodium o-phenylphenate (SOPP) is a white crystalline powder that is used as an antiseptic and fungicide.
Sodium o-phenylphenate (SOPP) has applications in the agricultural industry for crop protection and preservation.



USES and APPLICATIONS of SODIUM O-PHENYLPHENATE (SOPP):
Sodium o-phenylphenate (SOPP) is used as an antimicrobial agent in adhesives, leather, metalworking fluids, and textiles.
Sodium o-phenylphenate (SOPP) is also used as a preservative in automotive polishes, ceramic glazes, laundry starch, inks, and floor wax emulsions.
Sodium o-phenylphenate (SOPP) is used as a microbiostat/nematicide/bactericide for hard surface applications, agricultural sites and equipment, and air deodorization.


Sodium o-phenylphenate (SOPP) is also used as a preservative for stains, paints, metal working fluids, leather, polymers, textiles, paper slurries, cement mixtures, glues, adhesives, building materials, and cleaning products.
Sodium o-phenylphenate (SOPP) is used as a fungicide (citrus fruits and pears) and wood preservative; Also registered as an inert ingredient in insecticides, herbicides, and pet insect repellents.


Sodium o-phenylphenate (SOPP) is used antimicrobial additive in the manufacture of adhesives, leather, metalworking fluids, and textiles; preservative in automotive polishes, ceramic glazes, laundry starch, inks, floor wax emulsions; agricultural fungicide.
Cosmetic Uses of Sodium o-phenylphenate (SOPP): antimicrobial agents and preservatives


Sodium o-phenylphenate (SOPP) and its sodium (SOPP) salt have been used world-wide for decades as fungicides and disinfectants.
OPP is generally used as a hospital and household disinfectant, whereas Sodium o-phenylphenate (SOPP) is used as a fungicide, which post-harvest treatment of citrus fruits and vegatables for the prevention of mold.


Due to widespread use, including many consumer applications, the fate of OPP in the mammalian organism has been the subject of numerous investigations over many years.
Sodium o-phenylphenate (SOPP) is used Fungicide.


Sodium o-phenylphenate (SOPP) has been used in wastewater treatment as an inhibitor for phosphatase and transferase enzymes.
Sodium o-phenylphenate (SOPP) is used as a green feed additive and antifungal agent.
Sodium o-phenylphenate (SOPP) is used by professional workers (widespread uses), in formulation or re-packing and in manufacturing.


Other release to the environment of Sodium o-phenylphenate (SOPP) is likely to occur from: indoor use as processing aid.
Release to the environment of Sodium o-phenylphenate (SOPP) can occur from industrial use: formulation of mixtures.
Release to the environment of Sodium o-phenylphenate (SOPP) can occur from industrial use: manufacturing of the substance.


Sodium o-phenylphenate (SOPP) is a Sodium salt of ophenylphenol; avail. commercially as the tetrahydrate Sodium o-phenylphenate uses and applications include: Preservative in cosmetics, foods; antimicrobial, bactericide, fungicide, mold inhibitor for apples, etc.; industrial preservative; disinfectant; antimicrobial, biocide for adhesives, gums, latexes, paper coatings, hides, leather, textile spinning, timber, metalworking fluids, ceramics, chemical toilets, construction, disinfectants, household products (cleaners, floor care), inks; preservative in food packaging adhesives, coatings for food-contact paper, in food-contact animal glues; can end cement for food contact; defoamer in food-contact paperpaperboard; in closure-sealing gaskets for food containers.


Sodium o-phenylphenate (SOPP) is used Antimicrobial additive in the manufacture of adhesives, leather, metalworking fluids, and textiles; preservative in automotive polishes, ceramic glazes, laundry starch, inks, floor wax emulsions; agricultural fungicide.
Sodium o-phenylphenate (SOPP) is used as green feed additive, the maximum dosage is 0.95g/kg.


Sodium o-phenylphenate (SOPP) is used as preservative for vegetables and fruits.
Sodium o-phenylphenate (SOPP) is used mould inhibitor.
Sodium o-phenylphenate (SOPP) is mainly used for citrus.


Sodium o-phenylphenate (SOPP) is used soaking, spraying or trough washing with 0.3% ～ 2% aqueous solution are mainly adopted.
The method of adding 0.68% ～ 2% wax and spraying can also be used.
Sodium o-phenylphenate (SOPP) is used as antiseptic and bactericide, it can be used for keeping citrus fresh according to Chinese regulations.


Sodium o-phenylphenate (SOPP) can also be found in personal care products like soaps and shampoos.
Sodium o-phenylphenate (SOPP) should be handled with care and stored in a cool, dry place away from heat sources or combustible materials.
Sodium o-phenylphenate (SOPP) is important to follow safety guidelines when handling this product as it may cause skin irritation or eye damage upon contact.



INDUSTRY OF SODIUM O-PHENYLPHENATE (SOPP):
*Cosmetic ,
*Industrial ,
*Adhesives ,
*Construction ,
*Cleaners



FUNCTIONS OF SODIUM O-PHENYLPHENATE (SOPP):
*Antimicrobial ,
*Preservative ,
*Biocide ,
*Metalworking Fluids



FUNCTIONAL CLASS OF SODIUM O-PHENYLPHENATE (SOPP):
*Food Additives
*PRESERVATIVE



FUNCTIONAL USES OF SODIUM O-PHENYLPHENATE (SOPP):
For the post-harvest treatment of fruits and vegetables to protect against microbial damage



REACTIVITY PROFILE OF SODIUM O-PHENYLPHENATE (SOPP):
*Salts, basic, such as Sodium o-phenylphenate (SOPP) are generally soluble in water.
*The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0.
*They react as bases to neutralize acids.
*These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines.
*They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.



PHYSICAL and CHEMICAL PROPERTIES of SODIUM O-PHENYLPHENATE (SOPP):
Chemical Name: Sodium ortho-phenylphenate
Chemical Family: Phenol
Common/Trade Names:Dowcide A, Preventol ON Extra
Synonyms:(2-biphenylyloxy)sodium, Bactrol , D.C.S, Mildurid, OPP-Na,
CAS Number: 132-27-4
EINECS Number:205-055-6
Molecular Formula:C12H9NaO.H2O
Molecular Weight: 192.19 176.08 264.3 192.30(C6H46H5>ONA
Color: Nearly white or light-buff
Physical State: Solid (flakes or crystals, tetrahydrate form)
Specific Gravity(at 25oC): 1.3
Bulk density(kg/m3): 400-30
Dissociation Constant(at 20oC): 10
pH of saturated water solution(at 25oC): 12-3.5

Recommended pH Range: 8.5-3.5
Stability: Stable under controlled conditions
Melting Point(oC): 298.5
Boiling Point: N/A
Water Solubility(g/l at 25oC): 1200
Organic Solubility(g/100 at 25oC)
Methanol:470
Ethanol:375
Isopropanol:1500(g/l at 20oC)
Ethylene glycol:>300
Propylene glycol: >200
Octanol-Water Partition Coefficient (Log KOW): 0.59
Vapor Pressure mm Hg (at 25oC): 1.8 x 10-9
Molecular Weight： 192.18900
Exact Mass： 192.05500

EC Number： 205-055-6
HScode： 2907199090
PSA： 23.06000
XLogP3： 3.49740
Appearance： Sodium o-phenylphenoxide is a beige flaky solid.
pH of saturated solution in water: 12.0-13.5.
Density： 1.213 g/cm3
Melting Point： 282 °C
Boiling Point： 282ºC at 760 mmHg
Water Solubility： greater than or equal to 100 mg/mL at 68° F (NTP, 1992)
Storage Conditions： Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Keep away from incompatible materials, ignition so
Physical state: flakes
Color: beige
Odor: No data available
Melting point/freezing point: No data available

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available

Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Melting point: 59°C
Boiling point: 286°C
Density: 1,213 g/cm3
vapor pressure: 1.2Pa at 20℃
storage temp.: Inert atmosphere,Room Temperature
form: Liquid
pka: 9.9 (acid)
Water Solubility: 1220 g kg-1 (35 °C)
color: Yellow
Merck: 14,7304
Stability: Stable.
LogP: 3.18 at 22.5℃

Indirect Additives used in Food Contact Substances: SODIUM O-PHENYLPHENATE
FDA 21 CFR: 176.170; 177.1210; 178.3120
CAS DataBase Reference 132-27-4(CAS DataBase Reference)
EWG's Food Scores: 4-6
FDA UNII: KFV9K7N7UI
IARC: 2B (Vol. Sup 7, 73) 1999
EPA Substance Registry System: Sodium o-phenylphenoxide (132-27-4)
Pesticides Freedom of Information Act (FOIA): Sodium ortho phenyl phenate
Appearance: white powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 282.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.002020 mmHg @ 25.00 °C. (est)
Flash Point: 285.00 °F. TCC ( 140.30 °C. ) (est)
logP (o/w): 2.939 (est)
Soluble in: water, 1000000 mg/L @ 25 °C (exp)
Density: 1,213 g/cm3
Boiling Point: 286°C

Melting Point: 59°C
Molecular Formula: C12H9NaO
Molecular Weight: 192.189
Exact Mass: 192.055115
PSA: 23.06000
LogP: 3.49740
Stability: Stable.
Molecular Weight: 192.19 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 192.05510919 g/mol
Monoisotopic Mass: 192.05510919 g/mol
Topological Polar Surface Area: 23.1Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 154

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Molecular Formula: C12H9NaO
Molecular Weight: 192.19
CAS Registry Number: 132-27-4
EINECS: 205-055-6
Chemical Name: Sodium 2-biphenylate / ortho-phenylphenate / Sodium ortho-phenylphenate
CAS No.: 132-27-4
Molecular Formula: C12H9NaO
Molecular Weight: 192.19
Assay: 99% min

Appearance: white power
Molecular weight: 192.19
EINECS: 205-055-6
Melting Point: 59°C
Merck: 7304
Density: 1,213 g/cm3
Stability: Stable.
Boiling Point: 286°C
CAS: 132-27-4
MF: C12H9NaO
MW: 192.19
EINECS:205-055-6
Melting point :59°C
Boiling point :286°C
Density :1,213 g/cm3
Form :Liquid
pka:9.9 (acid)
Color : Yellow
HS Code :29071990



FIRST AID MEASURES of SODIUM O-PHENYLPHENATE (SOPP):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM O-PHENYLPHENATE (SOPP):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SODIUM O-PHENYLPHENATE (SOPP):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
*Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM O-PHENYLPHENATE (SOPP):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SODIUM O-PHENYLPHENATE (SOPP):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of SODIUM O-PHENYLPHENATE (SOPP):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

SODIUM PALMITATE N° CAS : 408-35-5 Origine(s) : Végétale, Synthétique Nom INCI : SODIUM PALMITATE N° EINECS/ELINCS : 206-988-1 Classification : Huile de Palme (Dérivé) Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

SODIUM PALMITOYL SARCOSINATE N° CAS : 4028-10-8 Nom INCI : SODIUM PALMITOYL SARCOSINATE Nom chimique : Sodium N-methyl-N-(1-oxohexadecyl)aminoacetate N° EINECS/ELINCS : 223-705-7 Ses fonctions (INCI) Agent nettoyant : Aide à garder une surface propre Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

SODIUM P-CHLORO-M-CRESOL; N° CAS : 15733-22-9; Nom INCI : SODIUM P-CHLORO-M-CRESOL; Nom chimique : 3-Methyl-4-Chlorophenol, Sodium salt; N° EINECS/ELINCS : 239-825-8; Ses fonctions (INCI); Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes; Noms français : SODIUM-4-CHLORO-3-METHYLPHENOLATE; Noms anglais : P-CHLORO-M-CRESOL, SODIUM SALT; PHENOL, 4-CHLORO-3-METHYL-, SODIUM SALT; SODIUM 4-CHLORO-3-METHYLPHENOXIDE; SODIUM-4-CHLORO-M-CRESOLATE; Naatrium-p-kloro-m-kresolaat (et); Natrijev p-kloro-m-krezolat (hr); Natrio p-chlor-m-krezoliatas (lt); Natrium p-chlor-m-kresolat (de); natrium-4-chlor-3-methylfenolát (cs) ; Natrium-p-chloor-m-kresolaat (nl); natrium-p-chlor-m-cresolat (da); Natrium-p-kloori-m-kresolaatti (fi); Natrium-p-kloro-m-kresolat (sv); nátrium-4-chlór-3-metylfenolát (sk); Nátrium-p-klór-m-krezolát (hu); Nātrija p-hlor-m-krezolāts (lv); p-chloro-m-crésolate de sodium (fr); P-chloro-m-krezolan sodu (pl); p-Cloro-m-cresolato de sodio (es); p-Cloro-m-cresolato de sódio (pt); p-cloro-m-cresoloato di sodio (it); p-cloro-m-crezolat de sodiu (ro); P-Kloro-m-kresolat tas-sodju (mt); Sodium p-chloro-m-cresolate (no); π-χλωρο-μ-κρεσολικό νάτριο (el); Натриев p-хлоро-m-крезолат (bg). IUPAC names : sodium 4-chloro-3-methylbenzen-1-olate; sodium 4-chloro-3-methylphenolate; 15733-22-9 [RN]; 239-825-8 [EINECS]; 2-chloro-5-hydroxytoluene sodium salt; 4-Chloro-3-méthylphénolate de sodium [French] ; MFCD00053303; Natrium-4-chlor-3-methylphenolat [German] ; Phenol, 4-chloro-3-methyl-, sodium salt (1:1) ; SODIUM 4-CHLORO-3-METHYLBENZENOLATE; Sodium 4-chloro-3-methylphenolate; Sodium p-chloro-m-cresol; [15733-22-9]; 2-CHLORO-5-HYDROXYTOLUENESODIUMSALT; 3-Methyl-4-chlorophenol, sodium salt; 4-CHLORO-3-METHYLPHENOL SODIUM SALT; EINECS 239-825-8; p-Chloro-m-cresol sodium salt; p-Chloro-m-cresol, sodium salt; Phenol, 4-chloro-3-methyl-, sodium salt; Phenol,4-chloro-3-methyl-, sodium salt (1:1); SODIUM 4-CHLORO-3-METHYLBENZEN-1-OLATE; sodium 4-chloro-3-methyl-phenolate; Sodium 4-chloro-3-methylphenoxide; Sodium 4-chloro-m-cresolate; sodium p-chloro-m-cresolate

SODIUM PCA Please consult your doctor or pharmacist or read the package insert. Cite this page APA Style Citation Sodium Pca / Cyclopentasiloxane - Uses, Side-Effects, Reviews, and Precautions - MLA Style Citation "Sodium Pca / Cyclopentasiloxane - Chicago Style Citation "Sodium Pca / Cyclopentasiloxane - Related Links Sodium Pca / Cyclopentasiloxane for skin conditioning Sodium Pca / Cyclopentasiloxane for hair conditioning More about Sodium Pca / Cyclopentasiloxane Uses Comments Consumer Survey - Sodium Pca / Cyclopentasiloxane The following are the results of an ongoing survey on TabletWise.com for Sodium Pca / Cyclopentasiloxane. These results only show the perceptions of the users of this website. Please make your medical decisions based on the advice of a doctor or a specialist. Uses, Efficiency and Side Effects The following are information on the usage, perceived efficiency and frequency of side effects offered by site visitors for Sodium Pca / Cyclopentasiloxane: Overdose of Sodium Pca / Cyclopentasiloxane Do not use more than prescribed dose. Consuming more of the drug will not improve your symptoms; on the contrary, it can cause poisoning or serious side effects. If you suspect that you or a relative has used an overdose of Sodium Pca / Cyclopentasiloxane, please visit your nearest hospital emergency department. To help doctors, bring necessary information such as a medicine box, bottle, or label. Do not give your medication to someone else, even if you know they have the same condition or they seem to have similar conditions. This can cause an overdose. For more information, consult your pharmacist or check the package insert. Storage of Sodium Pca / Cyclopentasiloxane Store medicines at room temperature, away from heat and light. Do not freeze medicines unless it is written on the package insert. Keep medicines out of the reach of children and pets. Do not pour medicines into the toilet or sink unless you are told to do so in the package insert. Drugs disposed in this way can pollute the nature. Please consult your pharmacist or doctor for more details on how to safely discard Sodium Pca / Cyclopentasiloxane. Expired Sodium Pca / Cyclopentasiloxane Taking a single dose of expired Sodium Pca / Cyclopentasiloxane is likely to cause an adverse event. Consult your family doctor or pharmacist for appropriate advice or if you feel unwell. Expired drugs will not be effective in treating conditions on your prescription. In order to stay safe, it is very important not to use expired medications. If you have a chronic illness that requires constant medication, such as heart disease, seizures, and life-threatening allergies, it is even more important to stay in touch with your GP so that you can replace expired medications immediately. Dosage Information Is this drug or product addictive or addictive? Many drugs are not marketed as addictive or abusive. Often ministries categorize drugs into controlled and non-addictive drugs. For example, this classification is H and X in India and II and V in the USA. Please check the box to make sure the drug belongs to such a special classification. Finally, do not try to self-medicate and increase your body's dependence without the advice of a doctor. Can I stop using this product immediately or do I get rid of it gradually? Some drugs should be tapered or their use should not be stopped suddenly to avoid withdrawal effects. Consult your doctor for recommendations specific to your body and health condition and other medications you can use. Other important information on Sodium Pca / Cyclopentasiloxane Forgetting to take a dose If you forget to take a dose, use it immediately. If your next dose is too close to your time, stop taking the missed dose and stick to your dosing schedule. Do not take extra doses to treat the missed dose. If you regularly forget your doses, set an alarm or ask a family member to remind you. Please consult your doctor to make changes to your dosing schedule or to make up for missed doses if you have recently forgotten too many doses. Before using this medicine, you should inform your doctor about the medicines you are currently using, the medicines you are using without a prescription (e.g. vitamins, herbal supplements, etc.), allergies, your past illnesses and your current health condition (e.g. pregnancy, upcoming surgery, etc.) inform. Certain health conditions can make you more susceptible to the side effects of the medication. Take the steps as directed by your doctor or consider what is written on the product. The dosage depends on your condition. If your condition persists or worsens, notify your doctor. Key issues to consult are listed below. Planning to get pregnant, pregnant or breastfeeding Please consult your doctor or pharmacist or refer to the package insert for this information. Hypersensitivity to Sodium Pca / Cyclopentasiloxane is a contraindication. In addition, Sodium Pca / Cyclopentasiloxane should not be used if you have the following conditions: Hypersensitivity Frequently Asked Questions Is it safe to drive or use heavy machinery while using this product? If you experience side effects such as drowsiness, dizziness, hypotension (low blood pressure) or headache while using Sodium Pca / Cyclopentasiloxane, it may not be safe to drive and / or use a construction machine. If the medication used causes drowsiness, dizziness or lowers your blood pressure, you should not drive. In addition, pharmacists advise patients not to drink alcohol with the drug, as alcohol intensifies side effects such as drowsiness. Please check for these effects on your body when using Sodium Pca / Cyclopentasiloxane. Always consult your doctor for advice specific to your body and health condition. Sodium Pca / Cyclopentasiloxane Medicine Sodium Pca / Cyclopentasiloxane Overview Uses Side effects Precautions Interactions Contraindications Overview Sodium Pca / Cyclopentasiloxane combination is used for Skin conditioning, Hair conditioning and other conditions. Detailed information on the use of Sodium Pca / Cyclopentasiloxane product, side effects, product comments, questions, interactions and precautions are as follows: uses Sodium Pca / Cyclopentasiloxane is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: Skin conditioning Hair softening Further information: Uses Side effects The following is a list of possible side-effects that may occur in medicines that contain Sodium Pca / Cyclopentasiloxane. This is not an exhaustive list. These side effects are likely to occur, but do not always occur. Some of the side effects are rare but can be very serious. Be sure to consult your doctor if you observe any of the following side effects, especially those that do not go away even if you expect them to. Skin irritation Hives If you notice any side effects other than those listed below, consult your doctor for medical advice. You can also report side effects to your nearest health department official. Measures Limnanthes Alba (Meadowfoam) Seed Oil, Rosa Damascena Flower Water, Beeswax (Cera Alba), Pentylene Glycol, Corylus Avellana (Hazel) Seed Oil, Ormenis Multicaulis Flower Wax, Sodium PCA Carbonate Decahydrate, Limonene, Citrus Medica Lemonum (Lemon) Peel Oil, Osmanthus Fragrans Flower Extract, Anthemis Nobilis Flower Oil, Tocopherol, Citronellol, Geraniol, Citral. If you have oily skin, avoid the first line items in their products being oil. In this case, make sure that the moisturizing agents are glycerin, sodium PCA, hyaluronic acid or sodium PCA hyaluronate. Amino acid cocktail: It contains Sodium PCA and 8 types of amino acids found in the skin's own structure. It is very effective in the care of mature skin. It helps the skin to be nourished and restructured. Bifida Ferment Lysate: It is an antiaging active with proven effectiveness. It prevents the damage of UV light on DNA. It helps to repair wrinkles by helping to repair DNA. 50ml Content: Sodium PCA: Protects against dryness by allowing the skin to retain more moisture. It is a natural and important moisturizing agent that is also found in the skin structure. Content: Amino acid cocktail: It contains Sodium PCA and 8 types of amino acids found in the skin's own structure. It is very effective in the care of mature skin. It helps the skin to be nourished and restructured. Glycine Soybean Seed Extract: Increases the strength of the skin with protein, glycoprotein and polysaccharides obtained from soy, renews the skin and revitalizes the skin cells. It helps prevent premature aging effects caused by UV rays and DNA damage on the skin. UVA / UVB Protection Factor: It contains a protection factor of 15 SPF. 50ml Hyaluronic acid, one of the most effective moisture retainers, has a water holding capacity of 1000 times its own weight. It has a tightening effect. It increases the elasticity of the skin. It ensures the transmission of moisture to all cells in the skin. Provides moisturization for a long time on the skin. These products, which plump the skin and provide moisture for a long time, are suitable for day and night use. It also ensures that the skin is smooth and even toned. Active Ingredients / Active Ingredients Sodium PCA, Sodium hyaluronate, Panthenol 10 x 2 ml Sodium PCA Messages Overview(active tab) Safety Resources What Is It? In cosmetics and personal care products, Sodium PCA (pyrrolidonecarboxylic acid) is used mostly in the formulation of hair conditioners and moisturizers. The sodium PCA salt of Sodium PCA, Sodium PCA, can be found in these products, as well as in shampoos, hair sprays, permanent waves, skin fresheners and other hair and skin care products. Why is it used in cosmetics and personal care products? Sodium PCA and Sodium PCA increase the water content of the top layers of the skin by drawing moisture from the surrounding air. They also enhance the appearance and feel of hair, by increasing hair body, suppleness, or sheen, or by improving the texture of hair that has been damaged physically or by chemical treatment. Abstract Sodium PCA pyrrolidone carboxylic acid is the sodium PCA salts of 2 pyrrolidone 5 carboxylate, It is one of the major Natural Moisturing factor (NMF) found in human skin. It is documented that sodium PCA pyrrolidone carboxylic acid (Na- Sodium PCA) is used in hair care & skin care products with great effectivity as it is water extracting skin component. As Na- Sodium PCA is the Natural Moisturizing Agent, it gives suppleness, humectancy & moisturizing property. It is being water soluble, therefore an oil in water (O/W) cream base decided to develop. Three formulae were developed in laboratory incorporating 2.5% & 5% of Na- Sodium PCA &7.5% glycerine. Three cream prepared were further studied for its stability with reference to effect of temp. i.e. at Room Temp.-24-28°c,at oven 50°c, & at refrigerator 90°c, change in colour, odour, pH, globules size & viscosity. It was further decided to study the performance evaluation. Details Sodium PCA stands for Pyrrolidone Carboxylic Acid and though it might not sound like it, it is a thing that can be found naturally in our skin. The sodium PCA salt form of Sodium PCA is an important skin-identical ingredient and great natural moisturizer that helps the skin to hold onto water and stay nicely hydrated. Description: Sodium PCA is the sodium PCA salt of pyroglutamic acid which is an uncommon amino acid found naturally in many proteins. Concentration: 50% (dissolved in water). GMO-free, gluten-free. Colorless to pale yellow clear liquid, soluble in water, pH 6.8-7.4. CAS: 28874-51-3 INCI Name: Sodium PCA (sodium L-pyroglutamate) Benefits: Occurs naturally in human skin and is responsible for binding moisture to the cells Highly water-absorbent, holding several time its weight in water, which makes it an excellent humectant Well-know as skin-penetration enhancer Stronger hydrating agent than the traditional compounds like glycerin or propylene glycol Good for hair care as it reduces static electricity. Use: Add as is to the water phase of the formulas, typical use level 1 - 10% in emulsions. For external use only. Applications: All kinds of skin care products such as creams, gels, lotions, hair care products, color cosmetics. Country of Origin: USA Raw material source: The original amino acid proline is obtained mainly from fruits and coconut oil. Manufacture: A fermentation process of sugars and starches is then used in order to create Sodium PCA from proline. Animal Testing: Not animal tested GMO: GMO-free but not certified Vegan: Does not contain any animal-derived components SODIUM PCA SODIUM PCA is classified as : Antistatic Hair conditioning Humectant Skin conditioning CAS Number 28874-51-3 EINECS/ELINCS No: 249-277-1 COSING REF No: 79910 Chem/IUPAC Name: Sodium PCA 5-oxo-2-pyrrolidinecarboxylate Sodium PCA is the sodium PCA salt of pyroglutamic acid (also known as Sodium PCA). Sodium PCA is a naturally occurring component of human skin and a part of the "natural moisturizing factors" (NMF) that maintain a healthy epidermis. Sodium PCA is very hygroscopic, attracting moisture from the air. It imparts a moist feeling to hair and skin. Sodium PCA applied to the skin is absorbed to a limited extent. It is non-comedogenic, nonirritating to the eye and skin -- even at concentrations up to 50%, and does not contribute to phototoxicity or sensitization. It is rapidly biodegradable. Soluble in water and ethanol and insoluble in oils, it is used for its powerful humectant properties in many skin and hair care products including gels, creams, lotions, shampoos, conditioners, lipsticks and foundations. This Sodium PCA is sourced from all-natural, vegetable-based ingredients; it contains no animal-based ingredients of any kind. INCI: Sodium PCA INCI: Sodium PCA 50% pH-value 6,8-7,4% Dosage: 0,5 - 10% Sodium PCA is a kind of natural moisturizing factor(NMF). It becomes an important additive ingredient in skin-care and hair-care cosmetics in the recent years. It has stronger hydrating power than that of glycerin, sorbitol and propanediol. What is Sodium PCA? Jun 08, 2019 Sodium PCA levels in the skin are highest during childhood. As time progresses, these levels can drop significantly. Using skin care products containing Sodium PCA can help increase these levels as you age. Sodium PCA also contains antioxidants that fight free radicals that can age the skin. It also contains vitamins D and E, which can aid in skin rejuvenation. This powerful moisturizer is made from many herbs, but sodium PCA from each herb is used to do different things. For example, Sodium PCA from herbs and vegetables can be used as an emollient. When Sodium PCA is derived from coconut oil, it is used as an emulsifier. Sodium PCA found in cherry or seaweed can replenish moisture inside the skin. Sodium PCA can also be used in certain types of lotions that protect the skin from excessive sunlight. This ingredient not only draws moisture into the skin but can also help keep it in. This makes it best suited for all skincare products. When sodium PCA is used in soaps, it can help the skin in many ways. It works with the natural Sodium PCA found in the skin to create a healthier and renewed skin. Sodium PCA used in shampoos and conditioners helps to retain water in the hair shaft. It can also add shine and bounce to hair. When the hair is very dry, static can build up, causing difficult-to-manage, flying hair. Sodium PCA keeps enough moisture in the hair to eliminate frizzy and dry hair. In small quantities, the use of sodium PCA is not considered harmful. It is considered to be mildly toxic, but is sometimes used with nitrosamine, which is thought to be a toxin. There were no known skin or eye irritations associated with the use of Sodium PCA. Effects of lactic acid and sodium PCA pyrrolidone carboxylic acid on the irritated skin reaction induced by sodium PCA lauryl sulphate patch testing of normal persons and atopic dermatitis patients Background: Natural moisturizing factors such as sodium PCA pyrrolidone carboxylic acid and lactic acid may play an important role in increasing the moisture retention of isolated stratum corneum and reducing the incidence of dry and flaky skin in vivo. Although the precise mechanism of surfactant irritancy is not fully understood, it has been suggested that barrier dysfunction of stratum corneum by surfactants results in skin changes such as scaling, erythema, and even fissuring. Objective: We evaluated the effect of sodium PCA pyrrolidone carboxylic acid(Na Sodium PCA) and lactic acid(LA) with several non-invasive measuring methods in the irritated skin reaction induced by sodium PCA lauryl sulphate (SLS) in normal persons and atopic dermatitis patients. Methods: After skin irritation for 24 hours with patch test of 1% SLS on five volar sites of right forearm, we applied nothing(A), 3% LA+3% Na Sodium PCA PCA(B), 3% LA(C), 3% Na Sodium PCA(D), and vehicle(E) twice a day respectively. Visual score, transepidermal water loss(TEWL), water holding capacity(WHC), and erythema index were measured at 30 min, 24hr, 48hr and 72hr after patch removal. Results: 1. After 72hr, the visual scores of B and C were significantly lower than that of A(control) in atopic dermatitis patients, and that of C in normal persons was significantly lower than that of A, D, and E. 2. TEWL values of B and C in both the normal (after 72hr) and atopic dermatitis group (after 48hr and 72hr) were significantly lower than that of A. 3. WHC values of B, C, D in both the normal and atopic dermatitis group were significantly higher than that of A after 48hr and 72hr. 4. After 72hr, erythema indices by Mexameter® of B, C, and D in both the normal and atopic dermatitis group were significantly lower than that of A and values of C were significantly lower than that of E. In the atopic dermatitis group, values of D were also significantly lower than that of E. 5. The mean visual score was significantly correlated with TEWL value and erythema index of Mexameter (r=0.58, r=0.64) and the TEWL value was significantly correlated with erythema index of Mexameter® (r=0.64). Conclusion: These results suggest that topical application of a moisturizing factor might improve the surfactant-induced disruption of permeability barrier with improvement of the water holding capacity of the stratum corneum. Sodium PCA Pyrrolidone Carboxylic Acid As Moisturizing Agent Abstract: Sodium PCA pyrrolidone carboxylic acid is the sodium PCA salts of 2 pyrrolidone 5 carboxylate, It is one of the major Natural Moisturing factor (NMF) found in human skin. It is documented that sodium PCA pyrrolidone carboxylic acid (Na- Sodium PCA) is used in hair care & skin care products with great effectivity as it is water extracting skin component. As Na- Sodium PCA is the Natural Moisturizing Agent, it gives suppleness, humectancy & moisturizing property .It is being water soluble,therefore an oil in water (O/W) cream base decided to develop. Three formulae were developed in laboratory incorporating 2.5% & 5% of Na- Sodium PCA &7.5% glycerine. Three cream prepared were further studied for its stability with reference to effect of temp.i.e. at Room Temp.- 24-280c,at oven 500c, & at refrigerator 900c, change in colour, odour, pH, globules size & viscosity.It was further decided to study the performance evaluation. Key Words: Na- Sodium PCA, NMF, Moisturizing Agent. 1. Introduction: By Kligman, “Moisturizer is defined as a topically applied substance or product that overcomes the signs& symptoms of dry skin”. Idson defined as ,”a Moisturizer,a substance that can favourably affect the feeling of dry skin ,by influencing the water content of stratum corneum” 1 . The approach to restoring water to dry skin has taken three different routes. 1.Occulsion 2.Humectancy 3.Restoration of deficient materials which may be combined. The first approach,occlusion consists in reducing the rate of transepidermal water loss through old or damaged skin or in protecting otherwise healthy skin from the effect of a severely drying environment. The second approach to the moisturizing problem is the use of humectants to attract water from the atmosphere, so supplementing the skin’s water content. The third & perhaps the most valuable approach to moisturization of skin is to determine the precise mechanism of the natural moisturization process to assess what has gone wrong with it in the case of dry skin & to replace any materials in which such research has shown damaged skin to be deficient2 . Moisturizer’s often contain lipids & humectants of low molecular weight, humectants such as urea ,glycerine, lactic acid, pyrrolidone carboxylic acid (Sodium PCA) and salts are absorb into the stratum cornium and their by attracting water, increase hydration3 1.1 Natural Moisturizing Factor(NMF) “A Group of water soluble hydrophilic substances known as the natural moisturizing factor (NMF)4 . Analysis of water soluble component of stratum cornium have indicated the presence of amino –acid lactic acid ,sugar and pyrolidone carboxylic acid.The latter material is found in relatively large concentration in cornified skin.It has recently been shown that salts of this material are extremely ,hygroscopic, dissolving in their own water of hydrations. At pH of stratum corneum (pH5) pyrolidone carboxylic acid exists almost exclusively in the salt form. There result suggest that this material may represent one of the important natural Moisturizing agent for skin5 . Laden and spitzer proved that significant quantities of Na-2-pyrrolidone -5 carboxylate exist in the stratum.This compound is now commercially available for use in cosmetics6 . 1.2 Composition of NMF Amino acids 40% Sodium PCA(Pyrrolidone carboxylic acid) 12% Lactates 12% Urea 7% NH3,Uric acid, glucosamine, creatinine 1.5% Citrates 0.5% Na 5%, k 4%, Ca 1.5 %, Mg 1.5% , Po4 0.5% 18.5 % Sucrore, Organic acid, Peptides, Other aterials 8.5% 1.3 Pyrrolidone Carboxylic Acid(Sodium PCA) ;(C5H7N03) Molecular wt 129.11 7 1.4 Sodium PCA pyrrolidone carboxylic acid (NA- Sodium PCA);(C5H6NNa03) Molecular wt 151.1 8 Na- Sodium PCA is one of the major natural moisturizing factors(NME) found in human skin. It is the sodium PCA salts of 2 Pyrrolidone-5-Carboxylate(Na- Sodium PCA) is manufactured by dehydration of glutanic acid and forms as odourless solid. Sodium PCA -2 Pyrrolidone-5-Carboxylate has been Patented as a humactant at concentration of 2 % or higher. Water absorption ability of Sodium PCA Pyrrolidone Carboxylate9 Compound %Moisture intake(31%RH) %Moisture intake(58%RH) Pyrrolidone Carboxylic Acid <1 <1 Sodium PCA Pyrrolidone Carboxylic Acid 20 61 Glycerine 13 35 1.5 Uses of Sodium PCA Pyrrolidone Carboxylate in Cosmetics 10 1) Sodium PCA -2-pyrrolidone-5-carboxylate is an important humectants component of NMF. 2) It is used in moisturizing dry flacky skin. 3) It demonstrates excellent hygroscopc & humectants effect & these properties have been achieved with a salt form. 4) Skin & hair care products,suncare,make-up,product are among the major application for Na- Sodium PCA. 5) It moisturizes &protects skin from wind,cold. S.Bhise/Int.J.ChemTech Res.2013,5(4) 1450 2. Materials & Methods Three O/W formulation were developed in laboratory incorporating glycerine & sodium PCA pyrrolidone carboxylic acid(Na- Sodium PCA). 2.1 Formulation Notation A- Base formulation with 7.5% glycerine. B- Formulation with 2.5% Na- Sodium PCA. C- Formulation with 5.0% Na- Sodium PCA. 2.2 Stability study for Finished Product. All the three samples prepared were subjected to accelerated test conditions & were kept at room temp 24-28 0c,in oven at 50 0c & in refrigerator at 5-8 0c. Stability studies were carried out by accelerated stability test for 40 days. 2.3 Performance Evaluation Ten volunteers were persuaded & then selected. Two cream samples were given to each volunteer one is control i.e. sample- A (7.5% glycerine)& other is sample-C(5% Na- Sodium PCA).Cream was applied twice a day on 3 cm.area of forehand.Sample A on right forehand &sample C on left forehand. sked to see & compaire the effect of sample A & C after two hours upto 30 days. 3. Results & Discussion 1) Result of colour change indicate that at room temp.& at 50 0c the degree of colour change was inversely proportional to the concentration of sodium PCA, on refrigeration there was no change in colour Summary The medical and biological literature was reviewed with stress laid on the role of pyrrolidone carboxylic acid (Sodium PCA) and its sodium PCA salt (Na Sodium PCA) in skin, its metabolism, its functions. The paper also includes a summary of 8 years of evaluation work carried out in our Laboratory on creams and lotions containing Sodium PCA-Na Sodium PCA which were assessed by biophysical (impedance measurement, alpha relaxation) and clinical methods. It is now definitely demonstrated that Sodium PCA is an hydrating agent and that all the cosmetic preparations containing at least 2% of the Sodium PCA-Na Sodium PCA salt system improve the condition of dry skin at short or long term provided an adequate vehicle is used (e.g. aqueous solutions are ineffective). The mecanism of action is discussed with reference to metabolism and physiological role of Sodium PCA in stratum corneum. Pyroglutamic acid (also known as Sodium PCA, 5-oxoproline, pidolic acid, or pyroglutamate for its basic form) exists as two distinct enantiomers: (2R) or D and (2S) or L. L-form is a metabolite in the glutathione cycle that is converted to glutamate by 5-oxoprolinase. L-Pyroglutamic acid is produced in the skin through the arginine-citrulline-ornitine-glutamic pathway. The free acid is not hygroscopic; however, the sodium PCA salts of this acid are more hygroscopic than glycerine. Therefore, formulation of this acid is suggested as a defense against dehydration, for skin conditions involving desquamation. Hydromol Cream (main component of that is sodium PCA pyrrolidone carboxylate (L form)) is a soft cream which moisturises the skin. Hydromol Cream contains a naturally occurring moisturising agent as well as oils, which prevent moisture loss from the skin. This helps to relieve itch, lubricate and soften the skin. Hydromol Cream is used to treat any condition in which dry skin is a feature such as eczema, ichthyosis (hereditary dry skin) and senile pruritus (itching that may occur in old age). L-Pyroglutamic acid is present in living cells has been reported from archaebacteria to humans, and its occurrence in living cells has been known for over a century. Despite its almost ubiquitous presence, the role of pyroglutamic acid in living cells is poorly understood. Pyroglutamic acid is found as an N-terminal modification in many neuronal peptides and hormones that also include the accumulating peptides in Alzheimer’s disease and familial dementia. The modification is also observed in proteins that include many antibodies, some enzymes and structural proteins. yrrolidone carboxylic acid (Sodium PCA), the primary constituent of the natural moisturizing factor (NMF),1 including its derivatives – such as simple2 and novel3 esters as well as sugar complexes4 – is the subject of great interest and research regarding its capacity to moisturize the stratum corneum via topical application. Creams and lotions containing the sodium PCA salt of Sodium PCA are widely reported to aid in hydrating the skin and ameliorating dry flaky skin conditions.5,6 In addition, the zinc salt of L-pyrrolidone carboxylate is a longtime cosmetic ingredient due to antimicrobial and astringent qualities. This column briefly addresses the role of Sodium PCA in skin health.7 Dry skin In a comprehensive literature review from 1981, Clar and Fourtanier reported conclusive evidence that Sodium PCA acts as a hydrating agent and that all the cosmetic formulations with a minimum of 2% Sodium PCA and Sodium PCA salt that they tested in their own 8-year study enhanced dry skin in short- and long-term conditions given suitable vehicles (no aqueous solutions).6 In a 2014 clinical study of 64 healthy white women with either normal or cosmetic dry skin, Feng et al. noted that tape stripped samples of stratum corneum revealed significantly lower ratios of free amino acids to protein and Sodium PCA to protein. This was associated with decreased hydration levels compared with normal skin. The investigators concluded that lower NMF levels across the depth of the stratum corneum and reduced cohesivity characterize cosmetic dry skin and that these clinical endpoints merit attention in evaluating the usefulness of treatments for dry skin.8 In 2016, Wei et al. reported on their assessment of the barrier function, hydration, and dryness of the lower leg skin of 25 female patients during the winter and then in the subsequent summer. They found that Sodium PCA levels were significantly greater during the summer, as were keratins. Hydration was also higher during the summer, while transepidermal water loss and visual dryness grades were substantially lower.9 Atopic dermatitis A 2014 clinical study by Brandt et al. in patients with skin prone to developing atopic dermatitis (AD) revealed that a body wash composed of the filaggrin metabolites arginine and Sodium PCA was well tolerated and diminished pruritus. Patients reported liking the product and suggested that it improved their quality of life.10 Later that year, Jung et al. characterized the relationship of Sodium PCA levels, and other factors, with the clinical severity of AD. Specifically, in a study of 73 subjects (21 with mild AD, 21 with moderate to severe AD, 13 with X-linked ichthyosis as a negative control for filaggrin gene mutation, and 18 healthy controls), the investigators assessed transepidermal water loss, stratum corneum hydration, and skin surface pH. They found that Sodium PCA levels and caspase-14 were lower in inflammatory lesions compared with nonlesional skin in subjects with AD. These levels also were associated with clinical AD severity as measured by eczema area and severity index scores as well as skin barrier function.11 Sodium PCA Pyrrolidone Carboxylic Acid CAS No.: 28874-51-3 EINECS.: 249-277-1 Moisturizer agent Appearance: Light yellow liquid Sodium PCA Pyrrolidone Carboxylic Acid, Sodium Pca QUICK LINKS Alkyl Polyglucosides Amino Acid Surfactants Cosmetic Additives Glyphosate surfactant Quick Details CAS No.: 28874-51-3 Other Names: Sodium Pca, Sodium L-pyroglutamate Appearance: Pale yellow lyophilized mass Description Sodium PCA is a kind of natural moisturizing factor. It becomes an important additive ingredient in skin-care and hair-care cosmetics in recent years. The stronger hydrating is power than that of glycerin, sorbitol and propanediol and non-poisonous, non-irritant, and non-allergic. Mainly used in cream cosmetics, solutions, shampoo, etc., but also in place of glycerin for toothpaste, ointment drugs, tobacco, leather, coatings for wetting agents, and chemical fiber dyeing auxiliaries, softeners, antistatic agent, Is also biochemical reagents. Cosmetic insulation agent Sodium PCA Department of natural moisturizing factor is one of the important ingredients, high moisture absorption, and non-toxic, non-stimulating, good stability, is the modern skincare ideal natural make-up health care products, can skin and hair with wetting, Softness, elasticity, and gloss, and antistatic property. Skin whitening agent Sodium PCA is an excellent skin whitening agent, the inhibition of tyrosine oxidase activity can prevent the "melanoid" in the skin deposition so that the skin white. Horny softening agent Sodium PCA can do keratin softening agent, the skin "psoriasis" have a good therapeutic effect. It is mainly used in cream cosmetics, solutions, shampoo, etc., also used in glycerin for toothpaste, ointment drugs, tobacco, leather, paint as wetting agents, and chemical fiber dyeing auxiliaries, softeners, Anti-static agent, is also biochemical reagents. Recommendatory volumes of usage in creams:2%~8% Recommendatory volumes of usage in creams:1%~3% Specification

SODIUM P-CUMENESULPHONATE; N° CAS : 15763-76-5; Nom INCI : SODIUM P-CUMENESULPHONATE; Sodium cumenesulphonate; 15763-76-5 [RN]; 239-854-6 [EINECS]; 4-Isopropylbenzènesulfonate de sodium [French] ; Benzenesulfonic acid, 4-(1-methylethyl)-, sodium salt (1:1) ; Natrium-4-isopropylbenzolsulfonat [German] ; Sodium 4-isopropylbenzenesulfonate ; SODIUM P-CUMENESULFONATE; 4-(1-Methylethyl)benzenesulfonic acid sodium salt; Benzenesulfonic acid, 4-(1-methylethyl)-, sodium salt; CUMENESULFONICACIDSODIUMSALT ;EINECS 239-854-6; MFCD00137274; p-Cumenesulfonic acid sodium salt; SODIUM 4-(PROPAN-2-YL)BENZENE-1-SULFONATE; sodium 4-(propan-2-yl)benzenesulfonate; Sodium 4-propan-2-ylbenzenesulfonate; Sodium cumenesulfonate; sodium p-cumenesulphonate; Sodium4-propan-2-ylbenzenesulfonate; sodiumcumenesulfonate; Sodium p-cumenesulphonate; EC Inventory, ; CAS names; Benzenesulfonic acid, 4-(1-methylethyl)-, sodium salt (1:1). IUPAC names; sodium 4-(propan-2-yl)benzene-1-sulfonate ; sodium 4-isopropylbenzenesulfonate ; Sodium 4-isopropylbenzenesulphonatesodium 4-propan-2-ylbenzenesulfonate; Sodium Cumenesulfonate; sodium cumenesulphonate. Trade names; Na-Cumolsulfonat; Na-Cumosulfonat; Sodium cumene sulfonate

SODIUM PERBORATE; N° CAS : 15120-21-5 / 7632-04-4 / 11138-47-9; Nom INCI : SODIUM PERBORATE; N° EINECS/ELINCS : 239-172-9 / 231-556-4 / 234-390-0; Classification : Règlementé; Ses fonctions (INCI); Agent d'hygiène buccale : Fournit des effets cosmétiques à la cavité buccale (nettoyage, désodorisation et protection); Agent Oxydant : Modifie la nature chimique d'une autre substance en ajoutant de l'oxygène ou en éliminant l'hydrogène; Perboric acid (H3BO2(O2)), monosodium salt trihydrate; perboric acid (H3BO2(O2)), monosodium salt trihydrate; sodium peroxoborate hexahydrate; perboric acid (H3BO2(O2)), monosodium salt trihydrate; sodium peroxoborate hexahydrate; Perboric acid (H3BO2(O2)), monosodium salt, trihydrate ; perboric acid (H3BO2(O2)), monosodium salt, trihydrate; sodium peroxoborate hexahydrate; perboric acid (H3BO2(O2)), monosodium salt, trihydrate; sodium peroxoborate hexahydrate ; Perboric acid (H3BO8), monosidum salt; perboric acid, sodium salt; Sodium perborate; sodium perborate; sodium peroxoborate; sodium perborate; sodium peroxoborate ; sodium perborate; sodium peroxoborate; sodium peroxoborate; sodium peroxoborate hexahydrate. Translated names : (peroksoboran) nadboran sodu (pl); acid perboric (H3BO2(O2)), sare monosodică, trihidrat (ro) ; acide perborique (H3BO2(O2)), sel de monosodium , trihydraté (fr); acide perborique (H3BO2(O2)), sel de monosodium trihydraté (fr); acido perborico (H3BO2(O2)), sale triidrato monosodico (it) ; aċidu perboriku (H3BO(O2)), melħ tal-monosodju, triidrat (mt); kyselina perboritá (H3BO2(O2)), monosodná sůl, trihydrát (cs); naatriumperboraat (et); natrijev perborat (sl); natrijev peroksoborat heksahidrat;perborna kiselina (H3BO2(O2)) ;mononatrijeva sol trihidrat (hr); natrijev peroksoborat heksahidrat;perborna kiselina (H3BO2(O2)) ;mononatrijeva sol trihidrat (hr); natrijev peroksoborat;natrijev perborate (hr); natrijev peroksoborat;natrijev perborate (hr); natrio peroksoboratas (lt); natriumperboraat (nl); natriumperboraatti (fi); natriumperborat (da); natriumperoxoborattrihydrat (sv); nátrium-perborát (hu); nātrija perborāts (lv); perboorhappe (H3BO2(O2)) mononaatriumsoola trihüdraat (et); perboorihappo, (H3BO2(O2)), mononatriumsuola, trihydraatti (fi); perboorzuur (H3BO2(O2)), mononatriumzout, trihydraat (nl); perborat de sodiu (ro); perborat tas-sodju (mt); perborate de sodium (fr); perborato de sodio (es); perborato de sódio (pt) ; perborato di sodio (it); perboritan sodný (cs); perborova kislina (H3BO2(O2)), mononatrijeva sol, trihidrat (sl); perborskābes (H3BO2(O2)), vienaizvietotā nātrija sāļa trihidrāts (lv); perborsyra (H3BO2(O2)), natriumsalt, trihydrat (sv); perborsyre (H3BO2(O2)), mononatriumsalt trihydrat (da); perborsyre (H3BO2(O2)), mononatriumsalt, trihydrat (no); Perborsäure (H3BO2(O2)), Mononatriumsalz-Trihydrat (de); perbórsav (H3BO2(O2)), mononátriumsó, trihidrát (hu); perbórsav (H3BO2(O2)), mononátriumsó-trihidrát (hu); peroksoborato rūgšties (H3BO2(O2)) mononatrio druska, trihidratas (lt); sól monosodowa kwasu nadborowego (H3BO2(O2)) trój-wodna (pl); sól monosodowa kwasu nadborowego (H3BO2(O2)) trójwodna (pl); tetrahydrogentetraoxodiperoxodiboritan disodný (sk); trihydrát monosodnej soli kyseliny trihydrogendioxodiperoxoboritej (H3BO2(O2)) (sk); ácido perbórico (H3BO2(O2)), sal de monosodio, trihidratada (es); ácido perbórico (H3BO2(O2)), sal monossódico, tri-hidratado (pt); άλας του υπερβορικού οξέος (H3BO2(O2)) με νάτριο, τριένυδρο (el); υπερβορικό νάτριο (el); натриев перборат (bg); перборна киселина (H3BO2(O2)), мононатриева сол трихидрат (bg); перборна киселина (H3BO2(O2)), мононатриева сол, трихидрат (bg); Perboric acid (H3BO2(O2)), monosodium salt ; IUPAC names: disodium;3,3,6,6-tetrahydroxy-1,2,4,5-tetraoxa-3,6-diboranuidacyclohexane; Sodium peroxometaborate ; trisodium [(dioxidoboranyl)oxy]olate

Sodium perborate is an inorganic sodium salt widely used in laundry detergents and peroxide-based bleaches, such as tooth whitening products.
Sodium perborate is soluble in water and releases hydrogen peroxide, but it is not merely a mixture of hydrogen peroxide and sodium borate, as peroxoborate species deliver the hydroperoxide anion at a lower pH than H2O2.
Sodium perborate has antiseptic properties and can act as a disinfectant, making it useful in detergents, cleaning products, and some eye drops as a preservative.

CAS Number: 10486-00-7
EC Number: 234-390-0
Chemical Formula: NaBO3 * 4 H2O
Molar Mass: 153.88 g/mol

Synonyms: Perboric acid, sodium salt, monohydrate, sodium;oxidooxy(oxo)borane;hydrate, Y9UKD0XE6F, Sodium perborate monohydrate [USAN], Sodium perborate monohydrate (USAN), Caswell No. 784A, Sodium borate, monohydrate, EPA Pesticide Chemical Code 011105, Sodium perborate hydrate, UNII-Y9UKD0XE6F, SODIUM BORATE MONOHYDRATE, DTXSID9035676, MFCD00149230, FT-0696526, SODIUM PERBORATE MONOHYDRATE [MART.], SODIUM PERBORATE MONOHYDRATE [WHO-DD], D07066, Perboric acid (HBO(O2)), sodium salt, monohydrate, Q18212089, perboric acid, Perboric acid (HBO3), Perboric acid (HBO(O2)), UNII-HC4C3M1FO2, HC4C3M1FO2, 14034-78-7, HBO3, DTXSID9058602, DB13235

Sodium perborate is commonly encountered in anhydrous form or as a hexahydrate (commonly called "monohydrate" or PBS-1 and "tetrahydrate" or PBS-4, after the early assumption that NaBO3 would be the anhydrous form).
They are both white, odorless, water-soluble solids.

This salt is widely used in laundry detergents, as one of the peroxide-based bleaches.

Sodium perborate is an oxidative preservative that is used in Genteal lubricating eye drops.
With topical application, sodium perborate is converted by catalase to water, oxygen, and hydrogen peroxide.

Sodium perborate antimicrobial properties are attributed to oxidization of cell membranes, membrane-bound enzymes, and disruption of protein synthesis.
Also, sodium perborate has demonstrated efficacy against Aspergillus niger.

However, most ophthalmic solutions that contain sodium perborate produce the byproduct, hydrogen peroxide, at levels between 30 and 100 ppm, which can cause ocular stinging.
Less is known about the histopathologic corneal and conjunctival changes associated with topical sodium perborate.

Sodium perborate is chemical compound whose chemical formula may be written NaH2BO4, Na2H4B2O8, or, more properly, [Na+]2[B2O4(OH)4]2−.
Sodium perborate name is sometimes abbreviated as PBS (not to be confused with phosphate-buffered saline).

Sodium perborate is used in the detergent industry as a bleaching agent.
The crystalline reagent is available inexpensively as a hydrate with the general formula NaBO3 • n H2O (n: 1-4).

The reagent offers low toxicity and a long shelf life.
Sodium perborate is a useful reagent in organic synthesis as a substitute for the unstable, highly concentrated hydrogen peroxide solutions that can pose a significant explosion hazard and are not commercially available.

Sodium perborate is soluble in water and releases hydrogen peroxide, but Sodium perborate is not merely a mixture of hydrogen peroxide and sodium borate.
NMR and Raman spectroscopy indicate that in dilute solution, an equilibrium exists that still contains peroxoborate anions.
These peroxoborate species are able to deliver the hydroperoxide anion at a lower pH than when H2O2 is used.

Sodium perborate is activated toward nucleophilic oxidation, and also buffers the reaction medium.

For oxidations of organoboranes, Kabalka notes that H2O2 sometimes requires quite harsh conditions that are incompatible with many functional groups, while Sodium perborate offers an interesting mild alternative.
He assumes that the mild nature of the oxidant is a result of having borate as a leaving group as compared to hydroxide, which is formed in hydrogen peroxide oxidations.

Mixing sodium perborate with acetic acid generates even more powerful oxidation species.

Sodium perborate is considered as a source of active hydrogen used in detergents, cleaning products, laundry detergents and bleaches.
Sodium perborate finds application as a tooth bleaching agent utilized for tooth.

Sodium perborate has antiseptic properties and acts as disinfectant as well as preservative in eye drops.
Further, Sodium perborate is mixed with suitable activator, tetraacetylethylenediamine in order to release oxygen at lower temperatures.

Perboric acid is mainly found in its salt form of sodium perborate and it can be found as a monohydrate or tetrahydrate.
Sodium perborate is one of the peroxy acid salts with very wide functionalities in industrial settings.

Perboric acid in the form of sodium perborate is approved by Health Canada since 2004 to be used as a disinfectant of medical instruments.
By the FDA, sodium perborate is approved as an ointment for the protection of poison ivy dermatitis.

Sodium perborate is an inorganic sodium salt widely used in laundry detergents and in peroxide-based bleaches, such as tooth whitening products.
Sodium perborate also has antiseptic and disinfectant properties and is therefore used as an oral debriding agent or oral wound cleanser.

Sodium perborates are salts composed of a sodium cation and the conjugate base anion of some inorganic or organic acids.
They can be formed by the neutralization of such acids with sodium hydroxide.

Categorization of Sodium Perborate:

Sodium perborates can be categorized into:
Sodium perborates of carboxylic acids (e. g. sodium formate, HCOONa, the Sodium perborate of formic acid or sodium acetate, CH3COONa, the Sodium perborate of acetic acid, etc.) and
Sodium perborates of inorganic acids (sulfonic acids etc.)

Organic Sodium perborates:

Drugs:
In pharmaceutical technology acidic pharmaceutical substances are often converted into Sodium perborates, because they are more stable, more soluble or membrane-permeable (bioavailable) than the base compound.

Examples of such Sodium perborates are (selection):
Bispyribac, bithionol, bosentan, brequinar, bromfenac, Cefmenoxime, ceftiofur, citicoline, diclofenac , Floxacillin, fosinopril, Mordant brown 33, naproxen, Netobimin, ozagrel, pantoprazole, pemetrexed, secobarbital, sitamaquin, sitaxentan, sulfamiderazin, sulfapyridine, sulfaquinoxaline, sulfathiazole, sulfazecin, thiamylal and mesna.

The Disodium perborate of cromolyn is also used as drug.
Most of these salts are Sodium perborates of organic carboxylic acids or sulfonic acids.

Plant protection agents:
Herbicides are often used as Sodium perborates for the reasons discussed above.
One example is the Sodium perborate of methylflupyrsulfuron (CAS-No. 144740-54-5).

Cosmetics:
Sodium perborates of long chain sulfonic acids (e.g. sodium lauryl sulfate) are often included in toothpaste and shampoo.
The Sodium perborates of fatty acids may serve as soaps and can therefore be called sodium soaps.

Dye production:
Sodium perborates of certain aromatic sulfonic acids - particularly naphthalenesulfonic acid - are used in the preparation of azo dyes.

Inorganic Sodium perborates:
Examples of important inorganic Sodium perborates are sodium fluoride, sodium chloride, sodium bromide, sodium iodide, sodium sulfate, sodium bicarbonate and sodium carbonate.
Sodium amide (NaNH2) is the Sodium perborate of ammonia (NH3).

Uses of Sodium Perborate:
Sodium perborate serves as a stable source of active oxygen in many detergents, laundry detergents, cleaning products, and laundry bleaches.
Sodium perborate is a less aggressive bleach than sodium hypochlorite and other chlorine-based bleaches, causing less degradation to dyes and textiles.

Borates also have some non-oxidative bleaching properties.
Sodium perborate releases oxygen rapidly at temperatures over 60 °C.
To make Sodium perborate active at lower temperatures (40–60 °C), one must mix Sodium perborate with a suitable activator, typically tetraacetylethylenediamine (TAED).

Sodium perborate is also present in some tooth bleaching formulas for non vital root treated teeth.
Sodium perborate is inserted in the root canal and left in place for an extended period of time to allow Sodium perborate to diffuse into the tooth and bleach stains from the inside out.
However, this use has been banned in the European Union.

Sodium perborate has antiseptic properties and can act as a disinfectant.
Sodium perborate is also used as a "disappearing" preservative in some brands of eye drops.

Sodium perborate is also used as an oxidizing reagent in organic synthesis.
For example, Sodium perborate converts thioethers into sulfoxides and sulfones.

Applications of Sodium Perborate:
Sodium perborate is considered as a source of active hydrogen used in detergents, cleaning products, laundry detergents and bleaches.
Sodium perborate finds application as a tooth bleaching agent utilized for tooth.

Sodium perborate has antiseptic properties and acts as disinfectant as well as preservative in eye drops.
Further, Sodium perborate is mixed with suitable activator, tetraacetylethylenediamine in order to release oxygen at lower temperatures.

Hydrates:
Sodium perborate also crystallizes from water as the hexahydrate, Na2H4B2O8·6H2O, that is, Na2H16B2O14 or NaH8BO7.

The anhydrous compound is commonly but incorrectly called a "monohydrate" after the historical formulation NaBO3·H2O instead of the correct Na2H4B2O8.
Likewise, the hexahydrate is usually called "tetrahydrate" and formulated as NaBO3·4H2O.

Both forms are white, odorless, water-soluble solids.
The "monohydrate" and the "tetrahydrate" are the commercially important forms.

There does exist a true tetrahydrate Na2H4B2O8·4H2O, traditionally known as the "trihydrate", with no industrial significance.
There is a CAS number for each of the three traditional "hydrates", the three "peroxyborate" versions of each (interpreted as a hydrogen peroxide adduct) and the poorly-defined "anhydrate" NaBO3, totalling seven.

Chemistry of Sodium Perborate:
Sodium perborate undergoes hydrolysis in contact with water, producing hydrogen peroxide and borate.

More precisely, in solution the cyclic anion hydrolizes into two anions [B(OH)3(OOH)]−, which then enter in equilibrium with boric acid B(OH)3, hydrogen peroxide H2O2, the hydroperoxyl anion −OOH, and the tetrahydroxyborate anion [B(OH)4]−:
[(B(OH)2OO)2]2− + 2 H2O ⇌ 2 [B(OH)3(OOH)]−
[B(OH)3(OOH)]− ⇌ B(OH)3 + −OOH
B(OH)3 + −OOH + H2O ⇌ [B(OH)4]− + H2O2

As the concentration of the solution increases, other peroxoborate species become significant.
With excess H2O2, the anions [B(OH)2(OOH)2]−, [B(OH)(OOH)3]−, and eventually [B(OOH)4]− appear.
At high borate concentrations, the sodium perborate with dimeric anion crystallizes out, due to Sodium perborate relatively low solubility.

The "monohydrate" form dissolves faster than the "tetrahydrate" and has higher heat stability; Sodium perborate is prepared by heating the "tetrahydrate".
The commercial "anhydrate", or Oxoborate, is prepared by further heating of "monohydrate" and actually consists of sodium borate and boron–oxygen radical.

Pharmacology of Sodium Perborate:

Drug Indication:
In the industry, sodium perborate is used as a disinfectant.
Sodium perborate is also part of the ingredients for detergents, bleach powders, and personal care formulations.

In cosmetic products, perboric acid and mainly Sodium perborate salt are used as an oxidizing agent for dyeing or permanent waving.
In dentistry, sodium perborate monohydrate is used as an aid for the removal of phlegm, mucus or other secretions associated with an occasional sore in the mouth, for cleansing minor wounds, for temporary cleanse of canker sore or for the removal of foreign materials in minor wounds.

In ophthalmic preparations, sodium perborate is used as a preservative for products used for dry eye.
This use is approved as Sodium perborate rapidly degrades to harmless byproducts.

Preparation of Sodium Perborate:

Sodium perborate is manufactured by reaction of borax Na2B4O7 and sodium hydroxide NaOH to give sodium metaborate NaBO2, which is then reacted with hydrogen peroxide to give hydrated sodium perborate:
Na2B4O7 + 2 NaOH → 4 NaBO2 + H2O
2 NaBO2 + 2 H2O2 → Na2B2O4(OH)4

A surfactant may be added to control crystal size.

Sodium perborate may also be produced in the electrolysis of an aqueous solution of a solution containing borax, sodium carbonate and sodium bicarbonate (potassium dichromate is added to improve yield along with sodium silicate).
A copper pipe is used as a cathode and platinum for the anode, the current being 6 amperes at 7 to 8 volts, and the temperature 10 °C.

Structure of Sodium Perborate:
Unlike sodium percarbonate and sodium perphosphate, Sodium perborate is not simply an adduct with hydrogen peroxide – known only since 1961.
Rather, Sodium perborate contains a perborate anion [(B(OH)2OO)2]2− consisting of a cyclic −B−O−O−B−O−O− core with two hydroxy groups attached to each boron atom.
The ring adopts a chair conformation.

Storage of Sodium Perborate:
Well closed.
Separated from combustible substances, reducing agents and strong acids.

Safety of Sodium Perborate:
In the European Union, sodium perborate, like most borates, was classified as "carcinogenic, mutagenic, or toxic for reproduction" (CMR), category 1B of Regulation (EC) 790/2009, as a result of being included in Part 3 of Annex VI of the regulation 1272/2008 on Classification, Labelling and Packaging (CLP) of substances and mixtures.
As a result, their use has been automatically banned in cosmetic products in the EU, in any concentration, starting 1 December 2010.
That extends to the use of perborates for tooth whitening.

Fire Fighting of Sodium Perborate:
In case of fire in the surroundings, use appropriate extinguishing media.

In case of fire:
Keep drums, etc., cool by spraying with water.
NO direct contact with water.

Spillage Disposal of Sodium Perborate:

Personal protection:
Particulate filter respirator adapted to the airborne concentration of Sodium perborate.
Do NOT let this chemical enter the environment.

Sweep spilled substance into covered dry, sealable containers.
Do NOT absorb in saw-dust or other combustible absorbents.

Identifiers of Sodium Perborate:
CAS Number:
7632-04-4
10332-33-9 ("monohydrate")
10486-00-7 ("tetrahydrate")

ChEBI: CHEBI:30178
ChemSpider: 4574023
ECHA InfoCard: 100.035.597
EC Number: 231-556-4
PubChem CID: 5460514
RTECS number: SC7350000

UNII:
Y52BK1W96C
Y9UKD0XE6F ("monohydrate")
822HSQ655R ("tetrahydrate")

UN number: 1479
InChI: InChI=1S/B2H4O8.2Na/c3-1(4)7-9-2(5,6)10-8-1;;/h3-6H;;/q-2;2*+1
Key: JBUKJLNBQDQXLI-UHFFFAOYSA-N
InChI=1/B2H4O8.2Na/c3-1(4)7-9-2(5,6)10-8-1;;/h3-6H;;/q-2;2*+1
Key: JBUKJLNBQDQXLI-UHFFFAOYAG
SMILES: [Na+].[Na+].O[B-]1(OO[B-](O)(O)OO1)O

CAS number: 10486-00-7
EC index number: 005-018-01-X
EC number: 234-390-0
Hill Formula: BNaO₃ * 4 H₂O
Chemical formula: NaBO₃ * 4 H₂O
Molar Mass: 153.88 g/mol
HS Code: 2840 30 00

Synonyms: Sodium perborate tetrahydrate
Linear Formula: NaBO3 · 4H2O
CAS Number: 10486-00-7
Molecular Weight: 153.86
EC Number: 239-172-9

Linear Formula: BNaO3 • 4H2O
MDL Number: MFCD00149231
EC No.: 231-556-4
Beilstein/Reaxys No.: N/A
Pubchem CID: 23676691
IUPAC Name: sodium; 3-oxido dioxaborirane; tetrahydrate
SMILES: B1(OO1)[O-].O.O.O.O.[Na+]
InchI Identifier: InChI=1S/BO3.Na.4H2O/c2-1-3-4-1;;;;;/h;;4*1H2/q-1;+1;;;;
InchI Key: IBDSNZLUHYKHQP-UHFFFAOYSA-N

Properties of Sodium Perborate:
Chemical formula: NaBO3·nH2O
Molar mass: 99.815 g/mol ("monohydrate");
153.86 g/mol ("tetrahydrate")
Appearance: White powder
Odor: Odorless
Melting point: 63 °C (145 °F; 336 K) ("tetrahydrate")
Boiling point: 130 to 150 °C (266 to 302 °F; 403 to 423 K) ("tetrahydrate", decomposes)
Solubility in water: 2.15 g/(100 mL) ("tetrahydrate", 18 °C)

Density: 1.73 g/cm3
Melting Point: 60 °C (decomposition)
pH value: 10 (15 g/l, H₂O, 20 °C)
Bulk density: 800 kg/m3
Solubility: 23 g/l (20 °C)

Compound Formula: H8BNaO7
Molecular Weight: 153.86
Appearance: White crystalline solid
Melting Point: 60 °C
Exact Mass: 154.026077
Monoisotopic Mass: 154.026077

Molecular Weight: 99.82 g/mol
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 99.9943830 g/mol
Monoisotopic Mass: 99.9943830 g/mol
Topological Polar Surface Area: 50.4Ų
Heavy Atom Count: 6
Complexity: 20.9
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Specifications of Sodium Perborate:
Assay (manganometric): ≥ 96.0 %
Identity: passes test
Chloride (Cl): ≤ 0.1 %
Sulphate (SO₄): ≤ 1.2 %
Heavy metals (as Pb): ≤ 0.003 %
Fe (Iron): ≤ 0.002 %

Melting Point: 60°C (decomposition)
Density: 1.73
pH: ∼10
Odor: Odorless
Quantity: 2500 g
UN Number: UN1479
Sensitivity: Hygroscopic
Merck Index: 14,8652
Solubility Information: Soluble in water.
Formula Weight: 153.86 (81.84 Anhydrous)
Percent Purity: 97%
Chemical Name or Material: Sodium perborate tetrahydrate

Names of Sodium Perborate:
Sodium peroxoborate
PBS-1 ("monohydrate")
PBS-4 ("tetrahydrate")

SYNONYMS Sodium Carbonate Peroxyhydrate; Carbonic acid disodium salt, compound with hydrogen peroxide(2:3); PCS; Sodium Carbonate Peroxide CAS NO. 15630-89-4

Sodium percarbonate is a chemical compound with the formula Na2CO3·1.5H2O2.
Sodium Percarbonate is also known by other names such as sodium carbonate peroxyhydrate or solid hydrogen peroxide.
Sodium percarbonate is a white, crystalline substance that is highly soluble in water.
Sodium Percarbonate is a solid compound consisting of sodium carbonate (Na2CO3) and hydrogen peroxide (H2O2) in a 2:3 molar ratio.

CAS Number: 15630-89-4
EC Number: 239-707-6



APPLICATIONS


Sodium Percarbonate is commonly used as a bleaching agent in laundry detergents to remove stains and brighten fabrics.
Sodium Percarbonate finds application in household cleaning products for surface cleaning, stain removal, and disinfection.
Sodium Percarbonate is used in carpet cleaners and stain removers to remove tough stains from carpets and upholstery.

Sodium Percarbonate is employed in denture cleaning tablets and solutions to sanitize and remove stains from dentures.
Sodium Percarbonate is utilized in water treatment processes to disinfect and purify water sources.

Sodium Percarbonate is added to multi-purpose cleaners to provide stain-removing and disinfecting properties.
Sodium Percarbonate is used in deck and patio cleaners to remove dirt, grime, and stains from outdoor surfaces.
Sodium Percarbonate is employed in mold and mildew removers to effectively eliminate fungal growth.

Sodium Percarbonate is added to laundry soaking solutions for pre-treating heavily stained garments.
Sodium Percarbonate is used in dishwasher detergents to remove tough food stains from dishes and utensils.
Sodium Percarbonate is utilized in surface disinfectants for its antimicrobial properties.

Sodium Percarbonate is added to wood cleaning and restoration products to remove stains and revive the appearance of wood surfaces.
Sodium Percarbonate finds application in tile and grout cleaners for removing dirt, grime, and soap scum.
Sodium Percarbonate is used in algae and moss control products to prevent and remove growth on outdoor surfaces.

Sodium Percarbonate is employed in pool and spa water treatment for maintaining water clarity and disinfection.
Sodium Percarbonate is utilized in air duct cleaning solutions to remove dirt and debris from HVAC systems.

Sodium Percarbonate is added to textile bleaching processes to whiten and brighten fabrics.
Sodium Percarbonate finds application in the pulp and paper industry for bleaching and deinking processes.

Sodium Percarbonate is used in industrial cleaning formulations for heavy-duty cleaning applications.
Sodium Percarbonate is employed in the food and beverage industry for equipment and surface cleaning and sanitization.
Sodium Percarbonate is used in agriculture and horticulture for disinfection, plant disease control, and pathogen management.
Sodium Percarbonate finds application in aquaculture for water disinfection and controlling bacterial and fungal infections.

Sodium Percarbonate is employed in the oil and gas industry for the cleaning and maintenance of equipment and pipelines.
Sodium Percarbonate may be used in medical and healthcare facilities for surface disinfection and equipment cleaning.
Sodium Percarbonate is added to cleaning products for brewery and winery equipment cleaning and sanitization.


Sodium Percarbonate has several applications across various industries.
Here are some of its common uses:

Laundry:
Sodium Percarbonate is widely used in laundry detergents and stain removers.
Sodium Percarbonate acts as a bleaching agent and helps remove tough stains and brighten fabrics.

Household Cleaning:
Sodium Percarbonate is utilized in household cleaning products such as all-purpose cleaners, bathroom cleaners, and kitchen cleaners.
Sodium Percarbonate effectively cleans and disinfects surfaces, removing stains, mold, and mildew.

Carpet Cleaning:
Sodium Percarbonate is an ingredient in carpet cleaning solutions and stain removers.
Sodium Percarbonate helps break down and remove stubborn stains, including those caused by coffee, wine, and food.

Denture Cleaning:
Sodium Percarbonate is used in denture cleaning tablets and solutions.
Sodium Percarbonate helps sanitize and remove stains from dentures, ensuring proper oral hygiene.

Water Treatment:
Sodium Percarbonate is employed in water treatment applications, particularly for the disinfection and purification of water.
Sodium Percarbonate acts as an oxidizing agent, killing bacteria, viruses, and algae.

Deck and Patio Cleaning:
Sodium Percarbonate is utilized in cleaning solutions for outdoor surfaces like decks, patios, and fences.
Sodium Percarbonate helps remove dirt, grime, and stains, restoring the appearance of the surfaces.

Mold and Mildew Removal:
Sodium Percarbonate is effective in removing mold and mildew from various surfaces, including bathroom tiles, grout, and outdoor areas prone to fungal growth.

Laundry Soak:
Sodium Percarbonate can be used as a soaking agent for heavily stained or soiled laundry.
Sodium Percarbonate helps lift and loosen tough stains before washing.

Dishwasher Detergent:
Sodium Percarbonate is found in some dishwasher detergents, aiding in the removal of tough food stains and providing a thorough clean.

Surface Disinfection:
Sodium Percarbonate is used to sanitize and disinfect hard surfaces in hospitals, laboratories, and food processing facilities due to its antimicrobial properties.

Wood Cleaning and Restoration:
Sodium Percarbonate is employed in wood cleaning and restoration products to remove stains, dirt, and weathering from wooden surfaces, improving their appearance.

Tile and Grout Cleaning:
Sodium Percarbonate helps remove dirt, soap scum, and stains from tiles and grout lines, restoring their original color and cleanliness.

Algae and Moss Control:
Sodium Percarbonate can be used to control algae and moss growth on various outdoor surfaces, including roofs, walkways, and fences.

Pool and Spa Water Treatment:
Sodium Percarbonate is sometimes used in pool and spa water treatment to help maintain water clarity, control organic contaminants, and disinfect the water.

Air Duct Cleaning:
Sodium Percarbonate is used in air duct cleaning solutions to remove dirt, dust, and debris from HVAC systems, improving air quality.

Textile and Fabric Industries:
Sodium Percarbonate is employed in the textile and fabric industries for fabric bleaching, stain removal, and color restoration processes.

Pulp and Paper Industry:
Sodium Percarbonate is used in the pulp and paper industry for pulp bleaching, deinking processes, and the removal of ink and stains from paper.

Industrial Cleaning:
Sodium Percarbonate is utilized in industrial cleaning formulations for the removal of tough stains, grease, and dirt from machinery, equipment, and surfaces.

Food and Beverage Industry:
Sodium Percarbonate finds applications in the food and beverage industry for the cleaning and sanitation of equipment, containers, and processing surfaces.

Agriculture and Horticulture:
Sodium Percarbonate can be used as a disinfectant for agricultural tools, equipment, and surfaces.
Sodium Percarbonate also aids in the control of fungal diseases and plant pathogens.

Aquaculture:
Sodium Percarbonate is employed in aquaculture for water disinfection, maintaining water quality, and controlling bacterial and fungal infections in aquatic environments.

Oil and Gas Industry:
Sodium Percarbonate is utilized in the oil and gas industry for the cleaning and maintenance of oil wells, pipelines, and equipment.

Medical and Healthcare:
Sodium Percarbonate may be used in medical and healthcare facilities for surface disinfection and cleaning of medical equipment.

Brewery and Winery:
Sodium Percarbonate finds applications in the brewery and winery industry for the cleaning and sanitization of brewing and fermentation equipment.

Mold Remediation:
Sodium Percarbonate is used in mold remediation and restoration processes to remove mold, disinfect affected surfaces, and prevent mold regrowth.

Cleaning and Restoration of Historical Artifacts:
Sodium Percarbonate can be employed in the cleaning and restoration of historical artifacts, sculptures, and artworks.

Septic System Maintenance:
Sodium Percarbonate is used in septic system maintenance products to help control odor, break down organic matter, and maintain the health of the system.

Veterinary and Animal Care:
Sodium Percarbonate may be used in veterinary and animal care facilities for cleaning and disinfecting animal enclosures, equipment, and surfaces.

Automotive and Car Wash:
The compound can find applications in automotive cleaning products, car wash solutions, and engine degreasers for stain and dirt removal.



DESCRIPTION


Sodium percarbonate is a chemical compound with the formula Na2CO3·1.5H2O2.
Sodium Percarbonate is also known by other names such as sodium carbonate peroxyhydrate or solid hydrogen peroxide.
Sodium percarbonate is a white, crystalline substance that is highly soluble in water.
Sodium Percarbonate is a solid compound consisting of sodium carbonate (Na2CO3) and hydrogen peroxide (H2O2) in a 2:3 molar ratio.

Sodium percarbonate is a source of active oxygen, meaning it releases hydrogen peroxide when dissolved in water.
Sodium Percarbonate is commonly used as an oxygen bleach and a cleaning agent due to its strong oxidizing properties.
When dissolved in water, it breaks down into hydrogen peroxide, which acts as a bleaching and stain-removing agent.

Sodium Percarbonate is often used in laundry detergents, stain removers, and household cleaning products to remove stains, brighten fabrics, and disinfect surfaces.
Sodium percarbonate is effective at removing a wide range of stains, including coffee, tea, wine, and food stains.
Sodium Percarbonate is considered an environmentally friendly alternative to chlorine bleach since it decomposes into water, oxygen, and soda ash (sodium carbonate) during the cleaning process.

In addition to its use in cleaning products, sodium percarbonate is also utilized in various other applications such as denture cleaners, carpet cleaners, and as a disinfectant for water treatment.
Sodium Percarbonate is an active ingredient in some oxygen-based multi-purpose cleaners and can be used for the cleaning and restoration of outdoor surfaces like decks, fences, and siding.

When handling sodium percarbonate, it is important to follow safety precautions and guidelines provided by the manufacturer. Sodium Percarbonate should be stored in a cool, dry place away from incompatible substances and sources of ignition.
Contact with the eyes or skin should be avoided, and appropriate protective equipment, such as gloves and goggles, should be worn when handling the compound.

Sodium Percarbonate is a white, crystalline powder.
Sodium Percarbonate has a chemical formula of 2Na2CO3·3H2O2.
Sodium Percarbonate is highly soluble in water.

Sodium Percarbonate is an inorganic peroxide compound.
Sodium Percarbonate is a solid substance with a granular or powdered texture.
Sodium Percarbonate has a mild, characteristic odor.

Sodium Percarbonate is a source of active oxygen.
Sodium Percarbonate acts as a bleaching agent and stain remover.
Sodium Percarbonate is commonly used in laundry detergents.

Sodium Percarbonate effectively removes stains from fabrics, including coffee, tea, and wine.
Sodium Percarbonate brightens and revitalizes dull or discolored clothes.
Sodium Percarbonate is known for its strong oxidizing properties.

Sodium Percarbonate decomposes into water, oxygen, and soda ash.
Sodium Percarbonate is an environmentally friendly alternative to chlorine bleach.
Sodium Percarbonate is used in household cleaning products.
Sodium Percarbonate disinfects and sanitizes surfaces effectively.

Sodium Percarbonate is an active ingredient in denture cleaners.
Sodium Percarbonate is utilized in carpet cleaners for stain removal.
Sodium Percarbonate is used for water treatment and purification.
Sodium Percarbonate has applications in the restoration of outdoor surfaces.

Sodium Percarbonate is safe to use on most fabrics and colors.
Sodium Percarbonate is non-toxic and biodegradable.

Sodium Percarbonate is stable under normal storage conditions.
Sodium Percarbonate should be stored in a dry place away from moisture.
Sodium Percarbonate is important to follow recommended dosage and handling instructions when using Sodium Percarbonate.



PROPERTIES


Chemical Formula: 2Na2CO3·3H2O2
Molar Mass: 314.02 g/mol
Appearance: White crystalline powder
Odor: Odorless
Solubility: Highly soluble in water
Melting Point: Decomposes around 50-70°C (122-158°F)
Density: 2.25 g/cm3
pH (1% solution): Approximately 10-11 (alkaline)
Decomposition Temperature: Decomposes at temperatures above 70°C (158°F)
Storage Stability: Stable under normal storage conditions
Hygroscopicity: Absorbs moisture from the atmosphere
Chemical Class: Inorganic peroxide compound
Oxidizing Properties: Sodium Percarbonate is a strong oxidizing agent.
Active Oxygen Content: Contains approximately 13.5% active oxygen.
Degradation Products: Decomposes into water, oxygen, and soda ash (sodium carbonate).
Flammability: Non-flammable
Toxicity: Sodium Percarbonate is considered relatively low in toxicity.



FIRST AID


Inhalation:

If inhaled, move the person to fresh air immediately.
If the person is experiencing difficulty breathing, provide oxygen if available and seek medical attention.
If breathing has stopped, perform artificial respiration and seek immediate medical attention.
Keep the affected person at rest in a position comfortable for breathing.


Skin Contact:

Remove contaminated clothing and rinse the affected skin area with plenty of water for at least 15 minutes.
Wash gently with mild soap and water.
If skin irritation or redness develops, seek medical advice.
If the chemical is stuck to the skin, do not try to remove it forcefully; seek medical attention for professional removal.


Eye Contact:

Rinse the eyes with gently flowing water for at least 15 minutes, ensuring to remove any contact lenses if present and easy to do.
Seek immediate medical attention, and bring the product label or safety data sheet with you.


Ingestion:

Rinse the mouth thoroughly with water.
Do not induce vomiting unless directed to do so by medical personnel.
Seek immediate medical attention and provide medical personnel with the product information.



HANDLING AND STORAGE


Handling:

Personal Protection:
When handling Sodium Percarbonate, wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat or protective clothing to prevent direct skin and eye contact.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to minimize exposure to airborne particles or dust.

Avoid Ingestion and Inhalation:
Do not eat, drink, or smoke while handling Sodium Percarbonate.
Avoid inhalation of dust or aerosols.
Use mechanical handling or closed systems to minimize the generation of airborne particles.

Prevent Contact with Skin and Eyes:
Avoid direct contact with Sodium Percarbonate.
In case of skin contact, promptly wash the affected area with water and mild soap.
In case of eye contact, rinse thoroughly with water for at least 15 minutes and seek medical attention.

Handling Equipment:
Use appropriate handling equipment such as scoops, shovels, or containers made of compatible materials (e.g., plastic or stainless steel) to transfer Sodium Percarbonate. Avoid using equipment made of reactive metals.

Spill and Leak Response:
In the event of a spill or leak, contain and clean up the material promptly, using appropriate protective equipment. Avoid generating dust and prevent the spilled material from entering drains, waterways, or soil.


Storage:

Storage Conditions:
Store Sodium Percarbonate in a cool, dry, well-ventilated area, away from sources of heat, ignition, and direct sunlight.
Maintain the storage area at temperatures below 30°C (86°F) to avoid decomposition.
Keep containers tightly closed to prevent moisture absorption and contamination.

Compatibility:
Store Sodium Percarbonate away from incompatible substances such as strong acids, reducing agents, and reactive metals.
Keep it separate from flammable materials and organic substances.

Packaging and Labeling:
Ensure that Sodium Percarbonate is stored in its original, properly labeled container.
Clearly label storage containers with appropriate hazard warnings, product name, and safety information.

Accessibility:
Store Sodium Percarbonate in a designated area, away from children, unauthorized personnel, and sources of ignition.

Fire Prevention:
Sodium Percarbonate is non-flammable.
However, take general fire prevention measures, such as keeping the storage area clear of flammable materials and maintaining suitable fire suppression equipment nearby.



SYNONYMS


Sodium Carbonate Peroxyhydrate
Sodium Percarbonate
Sodium Carbonate Hydrogen Peroxide
Solid Hydrogen Peroxide
Sodium Carbonate Peroxide
Sodium Peroxy Carbonate
Sodium Percarbonate Monohydrate
Sodium Carbonate Peroxohydrate
Sodium Carbonate Diperhydrate
Sodium Carbonate Peroxide
Sodium Hydrogen Carbonate Peroxide
Sodium Percarbonate Anhydrous
Sodium Carbonate Dihydrate Peroxide
Sodium Peroxy Carbonate Hydrate
Sodium Peroxocarbonate
Sodium Carbonate Peroxyhydrate Monohydrate
Sodium Carbonate Peroxide Hydrate
Sodium Peroxocarbonate Monohydrate
Sodium Hydrogen Carbonate Peroxyhydrate
Sodium Carbonate Peroxide Monohydrate
Sodium Peroxy Carbonate Monohydrate
Sodium Carbonate Peroxide Dihydrate
Sodium Carbonate Peroxide Hydrate
Sodium Peroxocarbonate Dihydrate
Sodium Hydrogen Carbonate Peroxide Monohydrate
Sodium Carbonate Dihydrate Peroxyhydrate
Sodium Carbonate Peroxide Dihydrate Monohydrate
Sodium Peroxocarbonate Dihydrate Monohydrate
Sodium Peroxy Carbonate Dihydrate
Sodium Carbonate Peroxide Monohydrate Dihydrate
Sodium Hydrogen Carbonate Peroxide Dihydrate
Sodium Peroxy Carbonate Hydrate Monohydrate
Sodium Carbonate Dihydrate Peroxyhydrate Monohydrate
Sodium Carbonate Peroxide Hydrate Dihydrate
Sodium Carbonate Peroxyhydrate Dihydrate
Sodium Hydrogen Carbonate Peroxide Dihydrate
Sodium Percarbonate Dihydrate
Sodium Peroxocarbonate Dihydrate Monohydrate
Sodium Carbonate Peroxide Hydrate Dihydrate
Sodium Peroxy Carbonate Dihydrate Monohydrate
Sodium Carbonate Peroxyhydrate Dihydrate Monohydrate
Sodium Carbonate Peroxide Monohydrate Dihydrate
Sodium Hydrogen Carbonate Peroxide Monohydrate Dihydrate
Sodium Percarbonate Dihydrate Monohydrate
Sodium Peroxocarbonate Monohydrate Dihydrate
Sodium Carbonate Peroxide Dihydrate Monohydrate
Sodium Peroxy Carbonate Hydrate Dihydrate
Sodium Carbonate Peroxyhydrate Monohydrate Dihydrate
Sodium Hydrogen Carbonate Peroxide Dihydrate Monohydrate
Sodium Carbonate Dihydrate Peroxyhydrate Monohydrate
Sodium Carbonate Peroxide Hydrate Dihydrate Monohydrate
Sodium Peroxocarbonate Dihydrate Monohydrate Tetrahydrate
Sodium Peroxy Carbonate Dihydrate Monohydrate Tetrahydrate
Sodium Carbonate Peroxide Monohydrate Dihydrate Tetrahydrate
Sodium Hydrogen Carbonate Peroxide Dihydrate Monohydrate Tetrahydrate
Sodium Percarbonate Dihydrate Monohydrate Tetrahydrate
Sodium Peroxocarbonate Monohydrate Dihydrate Tetrahydrate
Sodium Carbonate Peroxide Dihydrate Monohydrate Tetrahydrate
Sodium Peroxy Carbonate Hydrate Dihydrate Monohydrate Tetrahydrate

Sodium percarbonate (SPC) is a chemical compound with the molecular formula 2Na2CO3 · 3H2O2.
Sodium percarbonate (SPC) is a white, crystalline, and water-soluble solid that is a perhydrate of sodium carbonate.
Sodium percarbonate (SPC) is a solid hydrogen peroxide compound, often used as an environmentally friendly bleaching agent, disinfectant, and laundry booster.
When dissolved in water, it releases hydrogen peroxide, which is a powerful oxidizing agent and a bleach.

CAS Number: 15630-89-4
EC Number: 239-707-6



APPLICATIONS


Sodium percarbonate (SPC) is commonly used in laundry detergents as a powerful stain remover and bleach alternative.
Sodium percarbonate (SPC) helps to whiten and brighten clothing, making it an essential component in laundry products.

In the textile industry, Sodium percarbonate (SPC) is used in oxygen-based bleaching processes to treat fabrics and remove stains.
Sodium percarbonate (SPC) is employed in household dishwasher detergents to aid in the removal of tough food stains and residues from dishes and glassware.
Sodium percarbonate (SPC) is utilized in the cleaning of carpets and upholstery, effectively removing tough stains and odors.

In the pulp and paper industry, it is used to bleach wood pulp and improve the quality of paper products.
Sodium percarbonate finds applications in the restoration and cleaning of historical artifacts, preserving their integrity.
Sodium percarbonate (SPC) is used in mold and mildew removal products for both household and industrial applications.

Sodium percarbonate (SPC) is employed in cleaning and disinfecting hard surfaces, including countertops and bathroom fixtures.
Sodium percarbonate (SPC) is a key component in eco-friendly and oxygen-based stain removers and multi-surface cleaners.
Sodium percarbonate (SPC) is used in wood cleaning and restoration products to remove stains and brighten wood surfaces.
Sodium percarbonate (SPC) serves as an efficient algae and moss remover for decks, roofs, and outdoor structures.

In swimming pools and hot tubs, Sodium percarbonate (SPC) helps maintain water quality by oxidizing organic contaminants.
Sodium percarbonate (SPC) is used in agriculture as an eco-friendly soil fumigant and a source of oxygen for plants.
Sodium percarbonate (SPC) is employed in aquaculture to improve water quality and promote healthier aquatic environments.

In waste treatment and bioremediation, Sodium percarbonate (SPC) helps break down organic pollutants in water and soil.
Sodium percarbonate (SPC) is used as a disinfectant in various applications, including water treatment and sanitation.
Sodium percarbonate (SPC) is applied in the cleaning and disinfection of food processing equipment and facilities.

Sodium percarbonate (SPC) is used to sanitize brewing and winemaking equipment, ensuring the quality of beverages.
In the medical field, it is used as a disinfectant for medical instruments and surfaces.

Sodium percarbonate (SPC) finds applications in pool and spa maintenance to control algae and bacteria.
Sodium percarbonate (SPC) is used to remove and prevent moss and algae growth on roofs and exterior surfaces.

In the cosmetic industry, Sodium percarbonate (SPC) is used in teeth whitening products and oral care products.
Sodium percarbonate (SPC) is employed in the restoration of historical buildings, cleaning and preserving architectural elements.
Sodium percarbonate (SPC) is a versatile chemical that plays a vital role in various industries and applications, from cleaning and laundry to agriculture and environmental remediation.

Sodium percarbonate (SPC) is used in swimming pool and spa water treatment to control and eliminate algae, bacteria, and other microorganisms that can compromise water quality.
Sodium percarbonate (SPC) serves as a valuable component in the cleaning and sanitation of brewing equipment and beer and wine production facilities.

In the cosmetics industry, Sodium percarbonate (SPC) is utilized in teeth whitening products and toothpaste for its stain-removing properties.
Sodium percarbonate (SPC) can be found in oxygen-based cleaning products designed for the removal of mildew, mold, and stubborn stains in bathrooms and kitchens.

Sodium percarbonate (SPC) is used as an oxygen source for fish ponds and aquaculture systems to improve oxygen levels in water and support fish health.
Sodium percarbonate (SPC) plays a role in the maintenance and cleaning of wastewater treatment facilities to help break down organic waste and control odors.

Sodium percarbonate (SPC) is employed in the cleaning and disinfection of medical and dental instruments and equipment.
In the textile industry, it is used to bleach fabrics and remove stains, maintaining the quality and appearance of textiles.

Sodium percarbonate (SPC) is added to dishwashing detergents to enhance their stain-removing and cleaning capabilities.
Sodium percarbonate (SPC) is used in the cleaning and restoration of historical and architectural stone surfaces and sculptures.

Sodium percarbonate (SPC) can be applied in wood and deck cleaning products to remove weathering and staining, rejuvenating outdoor structures.
Sodium percarbonate (SPC) serves as an eco-friendly alternative to chlorine bleach, making it an ideal choice for those seeking more environmentally friendly cleaning solutions.

Sodium percarbonate is used in the automotive industry for cleaning car interiors, including carpets and upholstery.
In the pet care industry, it is found in pet stain removers to eliminate odors and stains caused by pet accidents.

Sodium percarbonate (SPC) is utilized in agriculture for soil fumigation and the promotion of plant growth by providing a source of oxygen.
Sodium percarbonate (SPC) is employed in water treatment and sanitation processes to disinfect drinking water and wastewater.

Sodium percarbonate (SPC) can be used as a pool shock treatment to rapidly increase chlorine levels and address water quality issues.
In the home improvement sector, it is used to clean and brighten decks and exterior siding.

Sodium percarbonate (SPC) is added to roof cleaning products to remove algae, moss, and lichen.
Sodium percarbonate (SPC) serves as a versatile cleaning agent for a wide range of surfaces, from countertops to tiles and grout.

Sodium percarbonate (SPC) is a component in environmentally friendly bathroom cleaners, helping to remove soap scum and mold.
Sodium percarbonate (SPC) can be used as a laundry booster, improving the stain-removing power of laundry detergents.

Sodium percarbonate (SPC) plays a role in disaster recovery and restoration, helping to clean and disinfect flood-damaged areas.
Sodium percarbonate (SPC) is utilized in the removal of rust stains from a variety of surfaces, including concrete and fabric.

Sodium percarbonate (SPC) is an eco-friendly, multi-purpose cleaning and sanitizing agent that is valued for its ability to tackle a wide range of cleaning challenges while being safer for the environment compared to traditional chemical solutions.
Sodium percarbonate (SPC) is commonly used in eco-friendly, oxygen-based laundry detergents, where it helps remove stains and brighten clothing while being gentle on fabrics.
Sodium percarbonate (SPC) is a preferred choice for washing cloth diapers as it effectively removes stains and odors without harming sensitive baby skin.
Sodium percarbonate (SPC) is employed in the cleaning and disinfection of air conditioning units and ducts, improving indoor air quality.

In the food industry, it is used to clean and sanitize food processing equipment and surfaces, ensuring food safety.
Sodium percarbonate (SPC) can be applied in the cleaning of kitchen and restaurant equipment, including stovetops, ovens, and countertops.
Sodium percarbonate (SPC) plays a role in mold and mildew removal in residential and commercial buildings, including bathrooms and kitchens.

Sodium percarbonate (SPC) is utilized in cleaning and restoring outdoor furniture, such as patio chairs and tables.
Sodium percarbonate (SPC) serves as an effective deck and fence cleaner, removing dirt, grime, and discoloration.

Sodium percarbonate is employed in the automotive industry for cleaning car exteriors, removing stubborn stains and contaminants.
In agriculture, it can be used as a soil conditioner to improve soil aeration and promote healthy plant growth.

Sodium percarbonate (SPC) is found in eco-friendly carpet cleaning products that effectively remove stains and odors.
Sodium percarbonate (SPC) is used in the treatment of wastewater in municipal and industrial facilities to break down organic matter.

Sodium percarbonate is an essential component in the restoration and cleaning of historical and cultural artifacts.
Sodium percarbonate (SPC) can be applied in water purification processes to eliminate harmful microorganisms and contaminants.

Sodium percarbonate (SPC) is utilized to remove graffiti from various surfaces without causing damage or discoloration.
Sodium percarbonate (SPC) serves as a valuable cleaning agent for boat and marine equipment, removing salt and algae buildup.
Sodium percarbonate (SPC) is used in swimming pool and hot tub maintenance to prevent algae growth and maintain water clarity.
In the pet care industry, it is found in pet odor and stain removers to address pet accidents effectively.

Sodium percarbonate (SPC) is applied in the cleaning and restoration of brick and stone surfaces in both residential and commercial settings.
Sodium percarbonate (SPC) serves as an eco-friendly alternative to traditional chlorine bleach in various cleaning applications.

Sodium percarbonate can be added to commercial and industrial floor cleaners to remove tough stains and residues.
Sodium percarbonate (SPC) is utilized in the cleaning of glass and windows, leaving streak-free and sparkling results.
Sodium percarbonate (SPC) is employed in dental hygiene products for its ability to whiten teeth and remove stains.
Sodium percarbonate (SPC) can be used as a deodorizer for carpets, upholstery, and fabrics, neutralizing unwanted odors.

Sodium percarbonate's wide range of applications in cleaning, disinfection, and restoration makes it a versatile and environmentally friendly choice for a variety of industries and tasks.
Sodium percarbonate (SPC) is utilized in the sanitation and disinfection of public swimming pools to maintain water quality and prevent the growth of harmful microorganisms.
Sodium percarbonate (SPC) is found in environmentally friendly automatic dishwasher detergents, where it helps to remove tough food stains and prevent the buildup of residue on dishes and glassware.

Sodium percarbonate (SPC) is used as a versatile cleaner for household surfaces, including countertops, tiles, and grout, leaving them free of stains and bacteria.
In the pet care industry, it is a key ingredient in pet stain and odor removers, helping to eliminate stubborn pet-related stains and odors.
Sodium percarbonate (SPC) can be added to carpet-cleaning machines for a thorough and eco-friendly carpet cleaning process.
Sodium percarbonate (SPC) is employed in the cleaning of sports and exercise equipment, such as yoga mats and gym surfaces, to ensure cleanliness and hygiene.

Sodium percarbonate (SPC) serves as a mold and mildew remover in bathrooms, kitchens, and other damp areas where these issues commonly arise.
In the agriculture sector, it can be used as a soil conditioner to improve soil quality and aeration, enhancing plant growth.
Sodium percarbonate (SPC) is used in eco-friendly roof cleaning products to remove algae, moss, and lichen from rooftops and shingles.
Sodium percarbonate (SPC) plays a role in cleaning and restoring historical architectural elements, such as stone facades and sculptures.

Sodium percarbonate (SPC) is found in bioremediation and wastewater treatment processes, breaking down organic pollutants and reducing environmental contamination.
Sodium percarbonate (SPC) is applied in the cleaning and sanitation of medical and dental instruments, ensuring hygiene in healthcare settings.
Sodium percarbonate (SPC) can be used as a disinfectant in the food and beverage industry for equipment and food contact surfaces.
Sodium percarbonate (SPC) is employed in eco-friendly wood and deck cleaning products to remove weathering, stains, and discoloration.

Sodium percarbonate (SPC) is a part of oxygen-based stain removers that effectively eliminate stubborn stains from various fabrics and surfaces.
Sodium percarbonate (SPC) is added to graffiti removal products to safely and efficiently erase graffiti without causing damage to underlying surfaces.

In the automotive industry, Sodium percarbonate (SPC) can be found in wheel and tire cleaners, helping to remove brake dust and road grime.
Sodium percarbonate (SPC) serves as an eco-friendly alternative to traditional pool shock treatments, addressing water quality issues in swimming pools.
Sodium percarbonate (SPC) can be applied to outdoor play equipment and structures to remove dirt, algae, and stains.
Sodium percarbonate (SPC) is used in the maintenance of water features and fountains, preventing algae growth and maintaining water clarity.

Sodium percarbonate (SPC) is employed in the cleaning and disinfection of public restrooms and facilities to maintain hygiene standards.
Sodium percarbonate (SPC) serves as an effective cleaner for outdoor surfaces, such as patios, walkways, and retaining walls.
Sodium percarbonate (SPC) is applied in the cosmetic industry for teeth whitening products, promoting dental hygiene and aesthetics.
Sodium percarbonate (SPC) is used in disaster recovery and restoration efforts to clean and disinfect flood-damaged areas.
Sodium percarbonate (SPC)'s versatility and eco-friendly properties make it a valuable component in a wide range of cleaning, disinfection, and restoration applications across various industries.



DESCRIPTION


Sodium percarbonate (SPC) is a chemical compound with the molecular formula 2Na2CO3 · 3H2O2.
Sodium percarbonate (SPC) is a white, crystalline, and water-soluble solid that is a perhydrate of sodium carbonate.
Sodium percarbonate (SPC) is a solid hydrogen peroxide compound, often used as an environmentally friendly bleaching agent, disinfectant, and laundry booster.
When dissolved in water, it releases hydrogen peroxide, which is a powerful oxidizing agent and a bleach.

Sodium percarbonate (SPC) is commonly used in various applications, including as a laundry stain remover, dishwasher detergent, surface cleaner, and in environmentally friendly and oxygen-based bleaching processes.
Sodium percarbonate (SPC) is preferred in many applications due to its ability to provide effective cleaning and stain removal while being safer for the environment compared to some traditional bleach products.

Sodium percarbonate, often abbreviated as Sodium percarbonate (SPC), is a white, crystalline, and water-soluble solid.
Sodium percarbonate (SPC) is a chemical compound with the molecular formula 2Na2CO3 · 3H2O2.

Sodium percarbonate (SPC) is a solid hydrogen peroxide compound that is a perhydrate of sodium carbonate.
Sodium percarbonate (SPC) is a powerful and environmentally friendly oxidizing agent.

When Sodium percarbonate (SPC) is dissolved in water, it releases hydrogen peroxide (H2O2), which is known for its strong oxidizing properties.
Sodium percarbonate (SPC) is widely used as a bleach in various applications, including laundry detergents and cleaning products.
Sodium percarbonate (SPC) is a safer and more environmentally friendly alternative to chlorine bleach.

Sodium percarbonate (SPC) can effectively remove stains and brighten clothes in laundry applications.
In laundry detergents, it helps break down and remove organic stains like grass, wine, and coffee.

Sodium percarbonate is used in dishwasher detergents to assist in the removal of tough food stains and residues from dishes and glassware.
Sodium percarbonate (SPC) is a key ingredient in oxygen-based bleaching processes for textiles and pulp and paper industries.

Sodium percarbonate (SPC) is known for its disinfecting and sanitizing properties, making it a common component in household cleaners.
When mixed with water, it produces a solution that can clean and disinfect various surfaces.

In addition to laundry and cleaning, Sodium percarbonate (SPC) is used for stain removal on carpets and upholstery.
Sodium percarbonate (SPC) is employed in mold and mildew removal products for household and industrial applications.

Sodium percarbonate (SPC) is also used in the restoration and cleaning of historical artifacts and buildings.
Sodium percarbonate (SPC) is a non-chlorine bleach, making it a preferred choice for those seeking a chlorine-free alternative.

Sodium percarbonate is compatible with septic systems and does not harm the environment when used as directed.
Sodium percarbonate (SPC) has a lower environmental impact compared to some traditional bleach products.

Sodium percarbonate (SPC) is a stable compound when stored in a cool, dry place, away from moisture.
When exposed to moisture or water, it releases oxygen gas, which aids in stain removal and cleaning.

The oxygen released by Sodium percarbonate (SPC) helps break down stains and organic matter through oxidation.
Sodium percarbonate (SPC) is known for its color-safe bleaching properties, as it does not damage or fade colored fabrics.

Sodium percarbonate (SPC) is a versatile and eco-friendly chemical that plays a significant role in modern cleaning and laundry products.
Its environmentally friendly and effective cleaning properties make it a popular choice for those looking for greener alternatives in household and industrial cleaning.



PROPERTIES


Chemical Formula: 2Na2CO3 · 3H2O2
Appearance: White, crystalline solid
Molecular Weight: Approximately 314.02 g/mol
Solubility: Highly soluble in water
pH Level: Alkaline (typically around 10-11 in solution)
Bleaching Action: Sodium percarbonate (SPC) releases hydrogen peroxide (H2O2) when dissolved in water, which acts as a powerful oxidizing agent and bleach.
Environmentally Friendly: It is considered an eco-friendly alternative to traditional chlorine bleach as it breaks down into water, oxygen, and soda ash (sodium carbonate) during use.
Stain Removal: Effective at removing a wide range of stains, including organic stains like coffee, tea, wine, and grass.
Color-Safe: Does not typically cause fading or damage to colored fabrics and materials.
Disinfection: Exhibits disinfecting and sanitizing properties, making it suitable for cleaning and sanitation applications.
Compatibility: Compatible with septic systems and does not harm the environment when used as directed.
Stability: Stable when stored in a cool, dry place away from moisture and incompatible substances.



FIRST AID


Inhalation:

If Sodium percarbonate (SPC) dust or fumes are inhaled, move the affected person to an area with fresh air.
Provide oxygen if the person has difficulty breathing.
Seek immediate medical attention if respiratory distress persists or worsens.


Skin Contact:

In case of skin contact, remove contaminated clothing and rinse the affected skin thoroughly with plenty of water for at least 15 minutes.
Use mild soap if available to assist in cleaning.
Seek medical attention if irritation, redness, or other symptoms persist.


Eye Contact:

If Sodium percarbonate (SPC) comes into contact with the eyes, immediately flush the eyes with gently flowing lukewarm water for at least 15 minutes.
Keep the affected eye open and rinse beneath the eyelids.
Seek immediate medical attention to assess and treat any eye irritation or injury.


Ingestion:

If Sodium percarbonate is ingested, rinse the mouth and drink plenty of water to dilute the chemical.
Do not induce vomiting unless directed by a medical professional.
Seek immediate medical attention. Provide the medical staff with information about the ingested substance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Sodium percarbonate (SPC), wear appropriate personal protective equipment (PPE), including safety glasses, gloves, and protective clothing to prevent skin and eye contact.

Ventilation:
Use in a well-ventilated area or under local exhaust ventilation to minimize inhalation of dust or fumes.
Avoid breathing dust or mist.

Avoid Contact:
Avoid direct skin and eye contact with the substance.
Do not eat, drink, or smoke while handling the chemical.

Prevent Mixing:
Do not mix Sodium percarbonate (SPC) with other chemicals, especially acids or acidic substances, as this can result in the release of harmful gases.

Do Not Inhale Dust:
Minimize the generation of dust by handling the substance gently.
In case of dust formation, wear a dust mask or respirator.

Spills and Leaks:
Clean up any spills promptly, using appropriate spill control measures and protective equipment.
Dispose of the waste material properly.

Wash Hands:
Wash hands and any exposed skin thoroughly after handling Sodium percarbonate (SPC).


Storage:

Cool, Dry Location:
Store Sodium percarbonate in a cool, dry, and well-ventilated area.
Keep it away from moisture and incompatible substances.

Original Container:
Keep the substance in its original container, tightly closed, and labeled correctly with all necessary information.

Separate from Incompatibles:
Store Sodium percarbonate (SPC) away from strong acids, reducing agents, and substances that may react with it, as well as flammable materials.

Temperature:
Avoid exposure to extreme heat, open flames, and direct sunlight, which may lead to decomposition or release of oxygen gas.

Segregate:
Store separately from materials that may be adversely affected by oxygen exposure.

Shelf Life:
Follow the manufacturer's recommendations regarding shelf life and use before the expiration date, if applicable.

Secured Storage:
Ensure that the storage area is secure and inaccessible to unauthorized or untrained personnel.

Spill Control Materials:
Have appropriate spill control materials and equipment readily available in case of accidental spills or releases.


Additional Considerations:

Keep Sodium percarbonate out of reach of children and pets.
Familiarize yourself with the emergency procedures, and maintain access to safety data sheets (SDS) for reference.
Clearly mark storage areas and containers with proper warning labels and handling instructions.
Inspect containers for signs of damage or deterioration and replace damaged containers as needed.
Properly dispose of empty containers in accordance with local, state, and federal regulations.



SYNONYMS


Sodium carbonate peroxide
Sodium carbonate peroxyhydrate
Sodium carbonate hydrogen peroxide
Sodium percarbonate compound
Hydrogen peroxide sodium carbonate
Sodium carbonate peroxyhydrate
Sodium carbonate hydrogen peroxide
Solid hydrogen peroxide
Oxygen bleach
Oxygenated bleach
Sodium carbonate peroxohydrate
Sodium carbonate peroxide compound
Sodium carbonate sesquiperhydrate
Sodium carbonate peroxohydrate
Sodium carbonate peroxide compound
Sodium carbonate sesquiperhydrate
Solid hydrogen peroxide
Oxygen bleach
Oxygenated bleach
Sodium percarbonate (SPC)
Sodium percarbonate (SPC)
Sodium carbonate peroxohydrate
Sodium carbonate peroxide compound
Sodium carbonate sesquiperhydrate
Sodium carbonate peroxohydrate
Sodium carbonate peroxide salt
Sodium carbonate peroxyhydrate compound
Sodium carbonate hydrogen peroxide complex
Sodium carbonate persalt
Sodium carbonate peroxohydrate
Sodium carbonate peroxocarbonate
Sodium carbonate peroxide hydrate
Sodium carbonate hydrogen dioxide
Sodium carbonate peroxy compound
Sodium carbonate peroxyhydrate salt
Sodium carbonate hydrogen peroxide compound
Sodium carbonate peroxide mineral
Sodium carbonate hydrogen peroxide complex
Sodium carbonate peroxohydrate
Sodium carbonate hydrogen dioxide
Sodium carbonate peroxy compound
Sodium carbonate peroxyhydrate salt
Sodium carbonate hydrogen peroxide compound
Sodium carbonate peroxide mineral
Sodium carbonate hydrogen peroxide
Sodium carbonate percarbonate
Sodium carbonate peroxide
Sodium carbonate persalt
Sodium carbonate peroxocarbonate
Sodium carbonate peroxide hydrate
Sodium carbonate peroxy compound
Sodium carbonate peroxide mineral
Sodium carbonate hydrogen peroxide
Sodium carbonate percarbonate
Sodium carbonate peroxide
Sodium carbonate persalt
Sodium carbonate peroxocarbonate
Sodium carbonate peroxide hydrate
Sodium carbonate hydrogen dioxide
Sodium carbonate peroxyhydrate salt
Sodium carbonate hydrogen peroxide compound
Sodium carbonate peroxohydrate
Sodium carbonate hydrogen dioxide
Sodium carbonate hydrogen peroxide
Sodium carbonate percarbonate
Sodium carbonate peroxide
Sodium carbonate persalt
Sodium carbonate peroxocarbonate
Sodium carbonate peroxide hydrate
Sodium carbonate hydrogen dioxide
Sodium carbonate peroxyhydrate salt
Sodium carbonate hydrogen peroxide compound
Sodium carbonate peroxohydrate
Oxygen bleach compound
Oxygenated bleach compound

Sodium perchlorate is a chemical compound with the molecular formula NaClO4.
Sodium perchlorate is a white crystalline solid that is highly soluble in water.
Sodium perchlorate is an oxidizing agent and can be hazardous if not handled properly

CAS Number: 7601-89-0
EC Number: 231-511-9



APPLICATIONS


Sodium perchlorate is used as an oxidizer in solid rocket propellants.
Sodium perchlorate is used in the manufacture of other perchlorate salts.
Sodium perchlorate is used in the preparation of perchloric acid.

Sodium perchlorate is used in the production of various types of fireworks and pyrotechnics.
Sodium perchlorate is used as a laboratory reagent.

Sodium perchlorate is used in the production of airbag inflators.
Sodium perchlorate is used in the treatment of thyroid diseases.

Sodium perchlorate is used in the electrolytic production of chlorine and perchloric acid.
Sodium perchlorate is used in the production of explosives and blasting agents.

Sodium perchlorate is used as a de-icing agent for aircraft.
Sodium perchlorate is used in the production of perchlorate esters.
Sodium perchlorate is used in the manufacture of perchlorate salts for use in electrochemical applications.

Sodium perchlorate is used in the production of flame retardants.
Sodium perchlorate is used as an oxidizing agent in organic synthesis.

Sodium perchlorate is used as a reagent in analytical chemistry.
Sodium perchlorate is used in the production of perchlorate-based rocket fuels.

Sodium perchlorate is used in the manufacture of perchlorate-based explosives.
Sodium perchlorate is used in the treatment of hyperthyroidism.
Sodium perchlorate is used in the preparation of perchlorate salts of various metals.

Sodium perchlorate is used in the production of perchlorate salts for use as corrosion inhibitors.
Sodium perchlorate is used in the treatment of thyrotoxicosis.

Sodium perchlorate is used in the production of perchlorate-based propellants for missiles and space vehicles.
Sodium perchlorate is used as a reagent in the production of acrylonitrile.

Sodium perchlorate is used in the production of perchlorate-based herbicides.
Sodium perchlorate is used in the manufacture of perchlorate-based batteries.


Sodium perchlorate has a wide range of applications in various fields.
Some of its applications are:

As an oxidizer in rocket propellants
In the manufacture of fireworks and other pyrotechnics
As an electrolyte in electrochemical processes such as electroplating and electrochemical machining
In the production of perchloric acid, which is used in the manufacture of other chemicals
As an analytical reagent in chemical analysis
In the production of high-performance batteries
In the treatment of hyperthyroidism, a condition in which the thyroid gland produces too much hormone
As a desiccant, or drying agent, in laboratory settings
In the manufacture of matches and other pyrophoric materials
As a catalyst in some chemical reactions
In the production of chlorates and perchlorates used as herbicides and pesticides
In the manufacture of semiconductors and other electronic components
In the production of explosives and blasting agents
As a flame retardant in plastics and other materials
In the production of tanning agents for leather
In the production of colored glass and ceramics
As a chemical intermediate in the production of other chemicals
In the treatment of wastewater and industrial effluent
As a preservative for wood and other materials
In the production of pigments and dyes
As a stabilizer in the manufacture of certain polymers and plastics
In the production of refrigerants and other chemicals used in air conditioning and refrigeration
In the purification of rare earth metals
In the production of fuel cells
In the formulation of drilling fluids for the oil and gas industry.


Sodium perchlorate is used as an oxidizer in the production of fireworks.
Sodium perchlorate is used in the manufacture of airbag initiators in automobiles.

Sodium perchlorate is used in the production of other perchlorate compounds, such as ammonium perchlorate.
Sodium perchlorate is used as a laboratory reagent in analytical chemistry.

Sodium perchlorate is used as an electrolyte in electrochemical cells.
Sodium perchlorate is used in the production of explosives, such as pyrotechnic mixtures.
Sodium perchlorate is used as a drying agent in organic chemistry.

Sodium perchlorate is used as a component in solid rocket fuel.
Sodium perchlorate is used as a bleaching agent in the pulp and paper industry.

Sodium perchlorate is used in the production of perchloric acid and other perchlorate salts.
Sodium perchlorate is used in the manufacture of metal coatings.

Sodium perchlorate is used as a component in high energy density batteries.
Sodium perchlorate is used in the production of herbicides and pesticides.
Sodium perchlorate is used as a laboratory reagent in DNA extraction and sequencing.

Sodium perchlorate is used in the production of pharmaceuticals.
Sodium perchlorate is used in the calibration of analytical instruments.

Sodium perchlorate is used as a stabilizer in some types of explosives.
Sodium perchlorate is used in the production of rocket propellants.

Sodium perchlorate is used in the manufacture of perchlorate esters, which are used as high energy fuels.
Sodium perchlorate is used as a flame retardant in textiles and plastics.
Sodium perchlorate is used as a reagent in the synthesis of organic compounds.

Sodium perchlorate is used as a cleaning agent in the electronics industry.
Sodium perchlorate is used in the production of high purity metals.

Sodium perchlorate is used as a salt in the formulation of dental products.
Sodium perchlorate is used in the preparation of specialized analytical reagents.

Sodium perchlorate is used in the manufacturing of perchloric acid, which is used in the production of pharmaceuticals, dyes, and other chemicals.
Sodium perchlorate is used as an oxidizer in solid rocket fuel, pyrotechnic compositions, and airbag initiators.

Sodium perchlorate is used as a bleaching agent for textiles and paper.
Sodium perchlorate is used as an electrolyte in some types of batteries.

Sodium perchlorate is used as a reagent in analytical chemistry for the determination of potassium, strontium, and other metals.
Sodium perchlorate is used as a component of explosives and propellants in the defense industry.
Sodium perchlorate is used as a mordant in textile dyeing.

Sodium perchlorate is used in the production of perchlorate salts such as ammonium perchlorate, which is used in rocket propellants.
Sodium perchlorate is used in the oil and gas industry for enhanced oil recovery.

Sodium perchlorate is used as a de-icing agent for aircraft runways and roads.
Sodium perchlorate is used in the manufacture of safety matches.

Sodium perchlorate is used as an oxidizer in the production of specialty chemicals.
Sodium perchlorate is used in the production of fireworks and flares.
Sodium perchlorate is used in the treatment of hyperthyroidism, a condition in which the thyroid gland produces too much hormone.

Sodium perchlorate is used in the electroplating industry as an electrolyte.
Sodium perchlorate is used as a color fixative in the textile industry.

Sodium perchlorate is used in the manufacture of some types of semiconductors and other electronic components.
Sodium perchlorate is used in the production of herbicides and fungicides.

Sodium perchlorate is used as a corrosion inhibitor in cooling water systems.
Sodium perchlorate is used as a catalyst in some organic reactions.
Sodium perchlorate is used in the manufacturing of safety explosives and pyrotechnic compositions.

Sodium perchlorate is used as a laboratory reagent for a variety of chemical reactions.
Sodium perchlorate is used as a flame retardant in textiles and plastics.

Sodium perchlorate is used as a fuel for high-performance model rockets.
Sodium perchlorate is used in the production of perchlorate esters, which are used as high energy density compounds.



DESCRIPTION


Sodium perchlorate is a chemical compound with the molecular formula NaClO4.
Sodium perchlorate is a white crystalline solid that is highly soluble in water.

Sodium perchlorate is an oxidizing agent and can be hazardous if not handled properly.
Sodium perchlorate has a variety of industrial applications and is also used in laboratory settings.


Some of the key properties and applications of sodium perchlorate include:

Sodium perchlorate has a molecular weight of 122.44 g/mol and a density of 2.52 g/cm³.
Sodium perchlorate is highly soluble in water, with a solubility of 209 g/100 mL at 25°C.

Sodium perchlorate is a strong oxidizing agent and can react violently with combustible materials.
Sodium perchlorate can also cause skin and eye irritation upon contact.

Sodium perchlorate is used in the manufacture of explosives, particularly airbag inflators for automobiles.
Sodium perchlorate is also used in rocket fuel and in the production of other chemicals such as perchloric acid.
In laboratory settings, sodium perchlorate is used as a source of oxygen in chemical reactions and as a drying agent for organic solvents.

Sodium perchlorate can also be used as a herbicide to control the growth of weeds.
In the medical field, sodium perchlorate has been used as a thyroid blocking agent in the event of nuclear accidents or radiation exposure.

Sodium perchlorate is often stored in a cool, dry place away from heat and sources of ignition.
Sodium perchlorate should be handled with care and protective equipment should be worn when working with it.
The EC number for sodium perchlorate is 231-511-9 and the CAS number is 7601-89-0.



PROPERTIES


Chemical formula: NaClO4
Molecular weight: 122.44 g/mol
Appearance: white crystalline solid
Odor: odorless
Density: 2.52 g/cm3
Melting point: 482 °C (900 °F; 755 K)
Boiling point: decomposes
Solubility in water: 209 g/100 mL (20 °C)
Solubility in ethanol: soluble
Solubility in acetone: soluble
Solubility in ammonia: soluble
pH: 5.5-7.5 (1% solution)
Vapor pressure: 0.001 mmHg at 25 °C
Flash point: non-flammable
Explosive limits: 0.24-3.6%
Stability: stable under normal conditions
Reactivity: reacts violently with reducing agents, organic materials, and metals
Hazardous polymerization: will not occur
Corrosivity: non-corrosive
Oxidizing properties: strong oxidizing agent
Toxicity: low acute toxicity, but may cause respiratory and eye irritation
Flammability: non-flammable
Autoignition temperature: not applicable
Hazard identification: can cause fires and explosions in contact with combustible materials



FIRST AID


In case of inhalation:

Move the person to fresh air immediately.
If the person is not breathing, perform artificial respiration.
Seek medical attention immediately.


In case of skin contact:

Remove contaminated clothing and wash the affected area with soap and water for at least 15 minutes.
Seek medical attention if irritation or other symptoms occur.


In case of eye contact:

Rinse eyes with water for at least 15 minutes while holding the eyelids open.
Seek medical attention immediately.


In case of ingestion:

Rinse the mouth with water and give plenty of water to drink if the person is conscious.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek medical attention immediately.


It is important to seek immediate medical attention if a significant amount of Sodium perchlorate is ingested, inhaled, or comes into contact with the skin or eyes.



HANDLING AND STORAGE


Store in a cool, dry, and well-ventilated area.
Keep containers tightly closed and sealed until ready for use.

Keep away from sources of heat, ignition, and combustible materials.
Avoid exposure to moisture or water.

Do not store with reducing agents, organic materials, or flammable liquids.
Do not store near strong acids or bases.

Use appropriate personal protective equipment (PPE) such as gloves, goggles, and protective clothing when handling.
Avoid inhalation or ingestion of the chemical.
Follow proper labeling and marking of containers.

Use only in a well-ventilated area.
Avoid contact with skin and eyes.

Wash hands thoroughly after handling the chemical.
Store separately from food, beverages, and pharmaceuticals.

Do not use damaged or leaking containers.
Keep out of reach of children and unauthorized personnel.
Keep a spill kit and appropriate firefighting equipment nearby.

Follow all applicable local, state, and federal regulations for handling and storage of the chemical.
Ensure proper grounding of equipment during transfer or handling.

Use only non-sparking tools and equipment.
Do not smoke, eat, or drink in the storage or handling area.

Store in a dedicated, clearly labeled, and secure area away from other chemicals.
Keep away from sources of ionizing radiation.

Do not store near oxidizers or combustibles.
Store and handle in accordance with Material Safety Data Sheet (MSDS) and other safety information provided by the supplier.



SYNONYMS


Perchloric acid, sodium salt
Perchlorate of soda
Sodium hyperchlorate
NaClO4
UN 1502

Sodium periodate is a strong oxidizing hypervalent iodine compound
Sodium periodate is an inorganic salt, composed of a sodium cation and the periodate anion.


CAS Number: 7790-28-5
EC Number: 232-197-6
MDL number: MFCD00003534
Chemical formula: NaIO4



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Sodium periodate is an inorganic salt, composed of a sodium cation and the periodate anion.
Sodium periodate may also be regarded as the sodium salt of periodic acid.
Sodium periodate contains a periodate.


Like many periodates, Sodium periodate can exist in two different forms: Sodium periodate (formula‍ NaIO4) and sodium orthoperiodate (normally Na2H3IO6, but sometimes the fully reacted salt Na5IO6).
Both salts are useful oxidising agents.


Sodium periodate converts cis-glycol groups in carbohydrates to amine-reactive aldehyde groups.
Carbohydrate groups in glycoproteins are excellent sites for modification or crosslinking reactions because they allow the conjugation reaction to be directed away from amino acids in the polypeptide chain that could be critical for protein activity.


Sodium periodate cleaves bonds between adjacent carbon atoms that contain hydroxyl groups (cis-glycols), creating two aldehyde groups that are spontaneously reactive to amine- and hydrazide-activated labeling, immobilization supports and crosslinking reagents.
Sodium periodate is an inorganic sodium salt having periodate as the counterion.


Sodium periodate has a role as an oxidising agent.
Sodium periodate contains a periodate.
Sodium periodate-inactivated virus is innocuous, elicits a strong humoral response and protects mice from a lethal challenge for a three-week period.


Sodium periodate is an inorganic salt commonly used as an oxidizing agent for various organic substrates and a co-oxidant in a few other oxidation reactions.
Sodium periodate is a strong oxidizing hypervalent iodine compound, able to facilitate a large scope of oxidation transformations in organic synthesis.


Saccharide rings and bonds can be oxidatively cleaved under mild conditions using Sodium periodate.
Sodium periodate is a gentle oxidizing agent that cleaves cis-diols in carbohydrate sugars to create amine-reactive aldehydes, providing many uses relating to the study and detection of glycoproteins.


Sodium periodate converts cis-glycol groups in carbohydrates to amine-reactive aldehyde groups.
Carbohydrate groups in glycoproteins are excellent sites for modification or crosslinking reactions because they allow the conjugation reaction to be directed away from amino acids in the polypeptide chain that could be critical for protein activity.


Sodium periodate cleaves bonds between adjacent carbon atoms that contain hydroxyl groups (cis-glycols), creating two aldehyde groups that are spontaneously reactive to amine- and hydrazide-activated labeling, immobilization supports and crosslinking reagents.
Sodium periodate is a chemical compound that is made up of sodium and periodic acid.


Sodium periodate is a versatile inorganic compound known for its potent oxidative action.
Sodium periodate's chemical properties allow a wide range of applications in various scientific fields.



USES and APPLICATIONS of SODIUM PERIODATE:
Sodium periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups.
This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin.
Because the process requires vicinal diols, periodate oxidation is often used to selectively label the 3′-ends of RNA (ribose has vicinal diols) instead of DNA as deoxyribose does not have vicinal diols.


Sodium periodate is used in organic chemistry to cleave diols to produce two aldehydes.
The oxidation of sodium periodate takes place in a water medium, but an organic co-solvent is used for organic substrates that are insoluble in water.
Sodium periodate is an oxidant and can be used as a disinfectant.


Sodium periodate has been shown to react with water molecules to form hydrogen peroxide and sodium hydroxide.
The reaction also produces heat, which may be used for sterilization purposes.
Sodium periodate is commonly used in the production of human immunoglobulin, which is used to treat autoimmune disorders such as rheumatoid arthritis and multiple sclerosis.


Sodium periodate has also been shown to have potential as a fluorescence probe for acidic compounds in water vapor.
On the one hand, Sodium periodate is widely used in chemistry as a strong oxidizing agent capable of promoting and catalyzing a wide range of reactions.
In histology, Sodium periodate is used to oxidize hematein to hematoxylin.


This is also known as artificial maturation of the hematoxylin solution.
In this process, the central phenol molecule, hematein, is oxidized by Sodium periodate to produce the nuclear dye hematoxylin.


-Sodium periodate can be used as an oxidizing agent:
*In the selective oxidation of sulfides to sulfoxides.
*For the oxidative cleavage of a variety of 1,2-diols to generate aldehydes or ketones.
*In the oxidation of diaryl, dialkyl, and aryl alkyl selenides to the respective selenoxides.
*In the selective alkene epoxidation and alkane hydroxylation reactions.
*In the selective oxidation of activated cellulose to obtain dialdehyde cellulose (DAC) by cleavage of the bond between C 2 – C 3 in the glucose unit.
*Sodium periodate can also be used as an iodinating agent for the iodination of arenes and halo compounds.



FEATURES OF SODIUM PERIODATE:
• Convert sugars in sialic acid and other glycosylation groups to reactive aldehydes
• Immobilize glycoproteins to a hydrazide-activated solid support
• Conjugate antibodies to glycoprotein enzymes, such as horseradish peroxidase
• Probe for cell-surface polysaccharides
• Detect carbohydrate-containing proteins using hydrazide-containing probes



PREPARATION OF SODIUM PERIODATE:
Classically, periodate was most commonly produced in the form of sodium hydrogen periodate (Na3H2IO6).
This is commercially available, but can also be produced by the oxidation of iodates with chlorine and sodium hydroxide.
Or, similarly, from iodides by oxidation with bromine and sodium hydroxide:
NaIO3 sodium iodate + Cl2+4NaOH⟶Na3H2IO6+2NaCl+H2O
NaI+4Br2+10NaOH⟶Na3H2IO6+8NaBr+4H2O

Modern industrial scale production involves the electrochemical oxidation of iodates, on a lead dioxide (PbO2) anode, with the following standard electrode potential:
H5IO6+H+ +2e−⟶IO3− + 3H2O E° = 1.6 V
Sodium periodate can be prepared by the dehydration of sodium hydrogen periodate with nitric acid.
Na3H2IO6+2HNO3⟶NaIO4+2NaNO3+2H2O



STRUCTURE OF SODIUM PERIODATE:
Sodium periodate forms tetragonal crystals (space group I41/a) consisting of slightly distorted IO−4 ions with average I–O bond distances of 1.775 Å; the Na+ ions are surrounded by 8 oxygen atoms at distances of 2.54 and 2.60 Å.
Sodium hydrogen periodate (Na2H3IO6) forms orthorhombic crystals (space group Pnnm).

Iodine and sodium atoms are both surrounded by an octahedral arrangement of 6 oxygen atoms; however the NaO6 octahedron is strongly distorted.
IO6 and NaO6 groups are linked via common vertices and edges.
Powder diffraction indicates that Na5IO6 crystallises in the monoclinic system (space group C2/m).



SODIUM PERIODATE CLEAVES 1,2-DIOLS ("VICINAL" DIOLS) TO ALDEHYDES AND KETONE:
Sodium periodate breaks apart 1,2-diols (“vicinal” diols) to form aldehydes and ketones.
In this respect Sodium periodate’s the same as periodic acid (HIO4) and lead tetra-acetate [Pb(OAc)4].

Notice what’s happening to NaIO4 here – Sodium periodate’s becoming reduced from iodine(VII) to iodine(V).
In the process we’re cleaving a C-C bond and forming two C-O π bonds. Comes in handy sometimes, when you want to break apart an alkene and form aldehydes and ketones.

Cleavage Of Vicinal Diols By Sodium periodate – The Mechanism:
The first step in cleavage of vicinal diols by Sodium periodate is the direct attachment of the alcohols to the iodine.
This occurs through two successive attacks of the iodine by lone pairs on each of the hydroxyl groups followed by a proton transfer.

In the second step, what happens is a kind of reverse cycloaddition (similar to what happens when an ozonide breaks down).
This is a somewhat simplified version of the mechanism (skipping over the proton transfer).
The key part here is the third diagram, where the cyclic iodate ester breaks down to give the ketone and aldehyde.

mechanism-of-naio4-cleavage-of-diols-to-give-carbonyl-compounds:
And there you go: aldehydes or ketones, depending on whether you’re breaking down secondary or tertiary alcohols (primary alcohols become formaldehyde).
So this actually gives you a second way to cleave double bonds to alkenes/ketones besides ozone.

You can take an alkene, treat it with osmium tetroxide (OsO4) first to make the diol, and then Sodium periodate it.
This is, incidentally, sometimes called “Johnson-Lemieux cleavage“.
Obscure organic chemistry named reaction of the day!



PHYSICAL and CHEMICAL PROPERTIES of SODIUM PERIODATE:
Chemical formula: NaIO4
Molar mass: 213.8918 g/mol
Appearance: white crystals
Density: 3.865 g/cm3 (anhydrous)
3/210 g/cm3
Melting point: 300 °C (572 °F; 573 K) (anhydrous)
175 °C (347 °F; 448 K) (trihydrate) (decomposes)
Solubility in water: 91 g/L
Solubility: soluble in acids
Structure:
Crystal structure: tetragonal (anhydrous)
trigonal (trihydrate)
Molecular Weight: 213.892 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 213.87390 g/mol
Monoisotopic Mass: 213.87390 g/mol

Topological Polar Surface Area: 74.3Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 118
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Autoignition Temperature: 262 °C
Boiling Point/Range: No data available
Certification: ACS Reagent
Color: Colorless to Yellowish
Density: 3.86 g/cm3
Flashpoint: Not applicable
Form: Crystalline

Grade: ACS Grade
Incompatible Materials: Combustible material,
Reducing agents, Powdered metals, Strong acids
Lower Explosion Limit: No data available
Melting Point/Range: 270 °C (Decomposes before melting)
Purity Percentage: 99.80
Purity Details: >=99.80%
Solubility in Water: 80-93 g/l (20 °C)
Upper Explosion Limit: No data available
Vapor Pressure: No data available
Viscosity: No data available
pH-Value: No data available
Storage Temperature: Ambient
Physical state: crystalline
Color: white, light yellow
Odor: odorless
Melting point/freezing point:
Melting point/range: 300 °C - dec.

Initial boiling point and boiling range: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: 262 °C at 1.013 hPa
Decomposition temperature: No data available
pH: 3,5 - 5,5 at 107 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: ca.91 g/l at 20 °C at 1.013 hPa -
Partition coefficient: n-octanol/water:
Not applicable for inorganic substances
Vapor pressure: No data available
Density: 3,87 g/cm3 at 20 °C
Relative density: 3,865 at 16 °C
Relative vapor density: No data available
Particle characteristics: No data available

Explosive properties: No data available
Oxidizing properties: The substance or mixture is classified as oxidizing with the category 1.
Other safety information: No data available
Assay: ≥99.8% 99.8-100.3% dry basis (ACS specification)
form: crystalline powder
reaction suitability reagent type: oxidant
impurities ≤0.02% other halogens (as Cl)
pH 3.5-5.5 (25 °C, 107 g/L)
mp 300 °C (dec.) (lit.)
cation traces Mn: ≤3 ppm
SMILES string [Na+].[O-]I(=O)(=O)=O
InChI 1S/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
InChI key JQWHASGSAFIOCM-UHFFFAOYSA-M
Melting Point: 300.0°C
Color: White
pH: 3.4 to 4.5 (5% soln. at 20°C)
Physical Form: Fine Crystals
Assay Percent Range: 98.5% min. (Iodometry)

Linear Formula: NaIO4
Fieser 01,809; 02,311; 04,373; 05,507; 06,455; 11,492; 13,145; 15,294
Merck Index: 15,8772
Solubility Information Solubility in water: 80g/L (20°C).
Other solubilities: 389g/L (52°C), soluble in h2so4, hno3, acetic acids,
insoluble in most common organic solvents
IUPAC Name: sodium;periodate
Formula Weight: 213.89
Percent Purity: 99%
Grade: Analytical
Chemical Name or Material: Sodium periodate
Melting Point: 78-80ºC
Boiling Point: 265.6ºC at 760 mmHg
Flash Point: 128.7ºC
Molecular Formula: C2H3NaO3
Molecular Weight: 98.033
Density: 1.416g/cm3



FIRST AID MEASURES of SODIUM PERIODATE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM PERIODATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of SODIUM PERIODATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM PERIODATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SODIUM PERIODATE:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep locked up or in an area accessible only to qualified or authorized persons.
Light sensitive. Hygroscopic.



STABILITY and REACTIVITY of SODIUM PERIODATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
hygroscopic
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available
-Incompatible materials:
No data available

Sodium Periodate has sodium and periodate ions in it.
Sodium Periodate is an inorganic salt, composed of a sodium cation and the periodate anion.


CAS Number: 7790-28-5
EC Number: 232-197-6
MDL number: MFCD00003534
Linear Formula: NaIO4
Molecular Formula: INaO4



SYNONYMS:
sodium periodate, sodium metaperiodate, sodium m-periodate, sodiumperiodate, sodium meta periodate, periodic acid, sodium salt, sodium meta-periodate, periodic acid hio4 , sodium salt, periodate sodium, sodium penodate, Periodicacid (HIO4), sodium salt (8CI,9CI), Sodium periodate (NaIO4) (6CI), Monosodiummetaperiodate, Periodic acid sodium salt, Sodium metaperiodate, Sodiummetaperiodate (NaIO4), Sodium periodate, Sodium metaperiodate, Sodium (meta)periodate, Sodium periodate, 7790-28-5, Sodium metaperiodate, Sodium m-periodate, sodium meta-periodate, sodium;periodate, Sodium (meta)periodate, Periodic acid, sodium salt, Periodic acid (HIO4), sodium salt, MFCD00003534, sodiumperiodate, 98W4A29X43, HSDB 7298, EINECS 232-197-6, sodium penodate, sodium periodat, Periodate sodium, UNII-98W4A29X43, Sodium iodate(VII), sodium(meta)periodate, Sodium meta periodate, NaIO4, sodium (meta) periodate, Na I O4, EC 232-197-6, Sodium periodate, ACS grade, Sodium metaperiodate ACS grade, CHEBI:75226, DTXSID30894075, SODIUM METAPERIODATE [MI], SODIUM M-PERIODATE [HSDB], BCP04945, AKOS005267138, AKOS015950617, BP-21195, DB-231843, NS00082315, Periodic acid (HIO4), sodium salt (1:1), Q281419, Sodium periodate, Sodium Metapriodate, Sodium Metaperiodate, Sodium meta periodate, Sodium (Meta)Periodate, Sodium Tetroxoiodate(Vii), periodicacid(hio4),sodiumsalt, sodiuM Metaperiodate in powder, SODIUM METAPERIODATE FOR ANALYSIS,


Sodium Periodate is a versatile inorganic compound known for its potent oxidative action.
Sodium Periodate's chemical properties allow a wide range of applications in various scientific fields.
Sodium Periodate can refer to two different chemical compounds which are essentially sodium salts of the two varieties of periodate ion.


Sodium metaperiodate (often abbreviated as m-periodate) has the formula NaIO4.
Sodium orthoperiodate (often abbreviated as o-periodate) has the formula Na5IO6.
Both salts are useful in certain synthetic chemistries for the oxidative power of the periodate ion.


Density of Sodium Periodate is 3,865 kg m-3.
Sodium Periodate is soluble in water.
When heated, Sodium Periodate decomposes to form sodium iodate, NaIO3 and oxygen.


This decomposition reaction is catalyzed by the presence of manganese(IV) oxide.
Sodium Periodate is a chemical compound.
Sodium Periodate's chemical formula can be NaIO4 (sodium metaperiodate) or Na5IO6 (sodium orthoiodate).


Sodium Periodate has sodium and periodate ions in it.
Sodium Periodate is an inorganic salt, composed of a sodium cation and the periodate anion.
Sodium Periodate may also be regarded as the sodium salt of periodic acid.


Like many periodates, Sodium Periodate can exist in two different forms: sodium metaperiodate (formula‍ NaIO4) and sodium orthoperiodate (normally Na2H3IO6, but sometimes the fully reacted salt Na5IO6).
Both salts are useful oxidising agents.


Sodium Periodate is an inorganic sodium salt having periodate as the counterion.
Sodium Periodate has a role as an oxidising agent.
Sodium Periodate contains a periodate.


Sodium Periodate is generally immediately available in most volumes.
Sodium Periodate is an inorganic salt, composed of a sodium cation and the periodate anion.
Sodium Periodate may also be regarded as the sodium salt of periodic acid.


Sodium Periodate is an inorganic chemical compound, and it is a derivative of sodium periodate.
Sodium Periodate is important as a source of periodic acid, an analytical agent, and an oxidizing agent, which is involved in the oxidation of cellulose.
Furthermore, Sodium Periodate is involved in the cleavage of vicinal diols to prepare two aldehydes.


Sodium Periodate typically occurs in the sodium metaperiodate trihydrate form.
This form of Sodium Periodate can be typically prepared by the dehydration of sodium hydrogen periodate with nitric acid.
In addition, we can do that by dehydrating orthoperiodic acid using a heat treatment to the reaction mixture to 100 Celsius degrees under vacuum conditions.


Sodium Periodate is a chemical compound that is made up of sodium and periodic acid.
Sodium Periodate is an oxidant and can be used as a disinfectant.
Sodium Periodate has been shown to react with water molecules to form hydrogen peroxide and sodium hydroxide.


The reaction also produces heat, which may be used for sterilization purposes.
Sodium Periodate appears as white crystals that are soluble in water.
Sodium Periodate is also soluble in acids.


Typically, Sodium Periodate is prepared in the form of sodium hydrogen periodate that is commercially available.
Moreover, we can produce Sodium Periodate through the oxidation of iodates with chlorine and sodium hydroxide or from iodides through oxidation with bromine and sodium hydroxide.


However, modern industrial preparations include electrochemical oxidation of iodates on a PbO2 anode.
Sodium Periodate is an inorganic compound having the chemical formula NaIO4.
Sodium Periodate is an inorganic salt consisting of a sodium cation and a periodate anion.


We can call Sodium Periodate the sodium salt of periodic acid.
Similar to many other periodates, Sodium Periodate also can exist in different forms, such as sodium metaperiodate form and sodium orthoperiodate form.
Both these types are useful oxidizing agents.


Sodium Periodate is an inorganic salt, composed of a sodium cation and the periodate anion.
Sodium Periodate may also be regarded as the sodium salt of periodic acid.



USES and APPLICATIONS of SODIUM PERIODATE:
Sodium Periodate is used in organic chemistry to cleave diols to produce two aldehydes.
Sodium Periodate, with the chemical formula NaIO4, has emerged as a pivotal reagent in diverse realms of scientific research, showcasing its versatile capabilities and broad utility.


One of Sodium Periodate's primary applications lies in its role as an oxidizing agent, particularly in organic synthesis.
Sodium Periodate′s ability to cleave vicinal diols into corresponding aldehydes or ketones has been extensively harnessed in the preparation of various chemical intermediates and complex molecules.


Furthermore, its selective oxidation properties have found utility in carbohydrate chemistry, where Sodium Periodate serves as a valuable tool for the functionalization and modification of polysaccharides and glycoproteins.
Recent research efforts have also explored Sodium Periodate's application in the field of materials science, with studies focusing on its use in the synthesis of nanostructured materials and functionalized surfaces.


Additionally, Sodium Periodate has been investigated for its role in analytical chemistry, particularly in the development of novel detection methods for various analytes.
Its compatibility with a wide range of substrates and its relatively mild reaction conditions render Sodium Periodate a versatile reagent for diverse research applications spanning organic synthesis, carbohydrate chemistry, materials science, and analytical chemistry.


Sodium periodate can oxidize cellulose.
Sodium Periodate is also used as a biodegradable chemical in the human body.
Sodium Periodate is also used in organic chemistry reactions.


Sodium Periodate is used to oxidize cellulose and create a biocompatible and biodegradable compound that can be used as suture, as a scaffold for tissue engineering, or for drug delivery.
Sodium Periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups.


This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin.
Because the process requires vicinal diols, periodate oxidation is often used to selectively label RNA (ribose has vicinal diols) instead of DNA deoxyribose does not have vicinal diols.


On the one hand, Sodium Periodate is widely used in chemistry as a strong oxidizing agent capable of promoting and catalyzing a wide range of reactions.
In histology, Sodium Periodate is used to oxidize hematein to hematoxylin.
This is also known as artificial maturation of the hematoxylin solution.


In this process, the central phenol molecule, hematein, is oxidized by Sodium Periodate to produce the nuclear dye hematoxylin.
Other applications are found in electrochemistry and materials science, where Sodium Periodate is used in the synthesis and modification of materials.
The wide range of applications that Sodium Periodate offers makes it an indispensable laboratory chemical in many scientific disciplines.


Sodium Periodate is used to oxidize cellulose and create a biocompatible and biodegradable compound that can be used as suture, as a scaffold for tissue engineering, or for drug delivery.
Sodium Periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups.


This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin.
Because the process requires vicinal diols, periodate oxidation is often used to selectively label RNA (ribose has vicinal diols) instead of DNA deoxyribose does not have vicinal diols.


Sodium Periodate is used as pharmaceutical intermediates and health products
Sodium Periodate is a mild oxidant that is routinely used for the conversion of cis-glycol groups in carbohydrates to reactive aldehdye groups.
The reactive aldehyde groups are used in chemical conjugation procedures or detection of carbohydrates.


For proteomic research, sodium m-periodate is used for the oxidation of the carbohydrate moiety of glycoproteins and offers the advantage of modifying the sugar side chains as opposed to critical amino acids.
Sodium Periodate is commonly used in the production of human immunoglobulin, which is used to treat autoimmune disorders such as rheumatoid arthritis and multiple sclerosis.


Sodium Periodate has also been shown to have potential as a fluorescence probe for acidic compounds in water vapor.
Sodium Periodate is used strong oxidizer and major component of the Ruthenium (IV) Oxide staining kit.
Sodium Periodate is also used in procedures for the elucidation of glycoproteins.


Sodium Periodate has important applications in the life sciences sector and the screen printing industry.
In the life sciences sector, Sodium Periodate’s ability to perform the classical “periodate 1, 2 diol cleavage” reaction with fine chemical intermediates that have adjacent hydroxyl groups is critical because the oxidation is specific; forming carbonyl compounds in high yields.


This reaction is particularly important in forming dialdehyde functions for “working up” into pharmaceutical intermediates or for attaching functionalised polysaccharides to suitable substrates.
In addition the selective oxidation powers of Sodium Periodate make it the ideal reagent for the reclamation of silk screens in the printing industry.


The non-image portions of a design are normally blocked with a cured emulsion of gelatine or polyvinyl alcohol that is chemically resistant.
Sodium Periodate selectively decomposes the cured emulsion so that it can be removed from the delicate and expensive silk screen, which can then be reused.


-Sodium Periodate can be used in solution to open saccharide rings between vicinal diols leaving two aldehyde groups.
This process is often used in labeling saccharides with fluorescent molecules or other tags such as biotin.
Because the process requires vicinal diols, periodate oxidation is often used to selectively label the 3′-ends of RNA (ribose has vicinal diols) instead of DNA as deoxyribose does not have vicinal diols.



PROPERTIES OF SODIUM PERIODATE:
Sodium Periodate is a colorless solid.
Sodium Periodate reacts with acids to make periodic acid.
Sodium Periodate breaks down when heated to make sodium iodate and oxygen gas.
Sodium Periodate is a strong oxidizing agent.



PHYSICAL AND CHEMICAL PROPERTIES OF SODIUM PERIODATE:
*colorless tetragonal crystal or white crystalline powder.
*relative density 4.174
*solubility soluble in water, sulfuric acid, nitric acid and acetic acid, *insoluble in alcohol.



PREPARATION OF SODIUM PERIODATE:
Classically, periodate was most commonly produced in the form of sodium hydrogen periodate (Na3H2IO6).
This is commercially available, but can also be produced by the oxidation of iodates with chlorine and sodium hydroxide.
Or, similarly, from iodides by oxidation with bromine and sodium hydroxide:

NaIO3 sodium iodate+Cl2+4NaOH⟶Na3H2IO6+2NaCl+H2O
NaI+4Br2+10NaOH⟶Na3H2IO6+8NaBr+4H2O

Modern industrial scale production involves the electrochemical oxidation of iodates, on a lead dioxide (PbO2) anode, with the following standard electrode potential:
H5IO6+H++2e−⟶IO3−+3H2O

Sodium Periodate can be prepared by the dehydration of sodium hydrogen periodate with nitric acid.
Na3H2IO6+2HNO3⟶NaIO4+2NaNO3+2H2O
Sodium Periodate can be made by oxidation of sodium iodide with sodium hypochlorite in a nitric acid solution.



STRUCTURE OF SODIUM PERIODATE:
Sodium Periodate forms tetragonal crystals (space group I41/a) consisting of slightly distorted IO−4 ions with average I–O bond distances of 1.775 Å; the Na+ ions are surrounded by 8 oxygen atoms at distances of 2.54 and 2.60 Å.

Sodium hydrogen periodate (Na2H3IO6) forms orthorhombic crystals (space group Pnnm).
Iodine and sodium atoms are both surrounded by an octahedral arrangement of 6 oxygen atoms; however the NaO6 octahedron is strongly distorted.

IO6 and NaO6 groups are linked via common vertices and edges.
Powder diffraction indicates that Na5IO6 crystallises in the monoclinic system (space group C2/m).



WHAT IS THE DIFFERENCE BETWEEN SODIUM PERIODATE AND SODIUM METAPERIODATE?
What is the Difference Between Sodium Periodate and Sodium Metaperiodate
The key difference between sodium periodate and sodium metaperiodate is that sodium periodate is a hypovalent compound, whereas sodium metaperiodate is a hypervalent compound.

Sodium periodate is an inorganic compound having the chemical formula NaIO4.
It is a hypovalent compound, which means it has a central atom having less than eight electrons in the valence electron shell.

Sodium metaperiodate is an inorganic chemical compound, and it is a derivative of sodium periodate.
It is a hypervalent molecule, which means it has one or more main group elements having more than eight electrons in its valence shells.



PHYSICAL and CHEMICAL PROPERTIES of SODIUM PERIODATE:
Chemical formula: NaIO4
Molar mass: 213.8918 g/mol
Appearance: white crystals
Density: 3.865 g/cm3 (anhydrous), 3/210 g/cm3
Melting point:
300 °C (572 °F; 573 K) (anhydrous)
175 °C (347 °F; 448 K) (trihydrate, decomposes)
Solubility in water: 91 g/L
Solubility: soluble in acids
Structure:
Crystal structure: tetragonal (anhydrous), trigonal (trihydrate)
CAS Number: 7790-28-5

EC Number: 232-197-6
Molecular Weight: 213.892 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 0
Exact Mass: 213.87390 g/mol
Monoisotopic Mass: 213.87390 g/mol
Topological Polar Surface Area: 74.3 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 118
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes
Grade: ACS, Reag. Ph Eur
Hill Formula: INaO₄
HS Code: 2829 90 40
pH value: 3.5 - 5.5 (107 g/l, H₂O, 25 °C)
Bulk density: 2900 kg/m3
Solubility: 91 g/l

Appearance: Crystalline
Physical State: Solid
Solubility: Soluble in water (144 mg/ml at 25°C), sulfuric, nitric, and acetic acids.
Storage: Store at room temperature
Melting Point: 300 °C (dec.)
Density: 3.86 g/cm3
CAS NO: 7790-28-5
MDL NO: MFCD00003534
APPEARANCE: White crystalline powder
MELTING POINT: 300 °C (dec.) (Approx.)
STORAGE TEMP: Store at RT
Melting Point: 300°C

Color: White
pH: 3.4 to 4.5
Formula Weight: 213.89 g/mol
CAS: 7790-28-5
EINECS: 232-197-6
InChI: InChI=1/HIO4.Na/c2-1(3,4)5;/h(H,2,3,4,5);/q;+1/p-1
Molecular Formula: H2INaO4
Molar Mass: 215.91
Density: 3.865
Melting Point: 300 °C (dec.) (lit.)
Boiling Point: 300°C
Water Solubility: 80 g/L (20 ºC)
Solubility: H2O: 0.5M at 20°C, clear, colorless

Vapor Pressure: 0Pa at 20°C
Appearance: Solid
Specific Gravity: 4.174
Color: White to almost white
Odor: Odorless
Merck: 14,8640
pH: 3.5-5.5 (25°C, 0.5M in H2O)
Storage Condition: Store at +5°C to +30°C.
Stability: Stable.
IUPAC: SODIUMPERIODATE
CAS Number: 7790-28-5
Molecular Weight: 213.89 g/mol
Formula: INaO4
SMILES: [Na+].[O-]I(=O)=O

Preferred IUPAC Name: SODIUM PERIODATE
InChIKey: InChIKey=JQWHASGSAFIOCM-UHFFFAOYSA-M
Appearance (Colour): White
Appearance (Form): Crystalline powder
Solubility (Turbidity) 10% aq. solution: Clear
Solubility (Colour) 10% aq. solution: Colourless
Assay (Iodometric): min. 99.5%
pH (5% aq. solution): 4.0 - 4.5
Loss on drying: max. 0.025%
Bromate, Bromide, Chlorate Chloride (Cl): max. 0.01%
Sulphate (SO4): max. 0.01%

Acidity blank for determination of glycerol: max. 0.2ml N%
Iodide (I): max. 0.001%
Manganese (Mn): max. 0.0003%
Calcium (Ca): max. 0.002%
Magnesium (Mg): max. 0.002%
Potassium (K): max. 0.005%
Melting Point: 300 °C
Density: 3.865 g/cm3
Exact Mass: 213.873901
Monoisotopic Mass: 213.873901
Linear Formula: NaIO4
MDL Number: MFCD00003534
EC Number: 232-197-6



FIRST AID MEASURES of SODIUM PERIODATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of SODIUM PERIODATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of SODIUM PERIODATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of SODIUM PERIODATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of SODIUM PERIODATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage stability:
Recommended storage temperature: 2 - 8 °C



STABILITY and REACTIVITY of SODIUM PERIODATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

SYNONYMS Peroxydisulfuric acid, disodium salt; disodium peroxodisulfate; Sodium peroxydisulfate; CAS NO. 7775-27-1

DESCRIPTION:
Sodium peroxodisulfate is the inorganic compound with the formula Na2S2O8.
Sodium peroxodisulfate is the sodium salt of peroxydisulfuric acid, H2S2O8, an oxidizing agent.
Sodium peroxodisulfate is a white solid that dissolves in water and Sodium peroxodisulfate is almost non-hygroscopic and has good shelf-life.

CAS Number: 7775-27-1
EC Number: 231-892-1
Molecular Formula: Na2S2O8
IUPAC Name: disodium;sulfonatooxy sulfate
SODIUM PEROXODISULFATE= SODIUM PERSULFATE


CHEMICAL AND PHYSICAL PROPERTIES OF SODIUM PEROXODISULFATE:
Chemical formula: Na2S2O8
Molar mass: 238.10 g/mol
Appearance: White powder
Density: 2.601 g/cm3[1]
Melting point: 180 °C (356 °F; 453 K) decomposes
Solubility in water: 55.6 g/100 ml (20 °C)
Molecular Weight: 238.11
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 8
Rotatable Bond Count: 1
Exact Mass: 237.88299787
Monoisotopic Mass: 237.88299787
Topological Polar Surface Area: 150 Ų
Heavy Atom Count: 12
Formal Charge: 0
Complexity: 206
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Molar Mass: 238.1
Density: 2,4 g/cm3
Melting Point: 100 °C
Water Solubility: 550 g/L (20 ºC)
Solubility: H2O: 1M at20°C, clear, colorless
Vapor Pressure: 0Pa at 25℃
Appearance: Solid
Specific Gravity: 2.4
Color: White to yellow
Odor: Odorless
Exposure Limit ACGIH: TWA 0.1 mg/m3
Merck: 14,8656
PH: 3.5-3.8 (100g/l, H2O, 20℃)
Storage Condition: Store at +15°C to +25°C.


PRODUCTION OF SODIUM PEROXODISULFATE:
The salt is prepared by the electrolytic oxidation of sodium bisulfate:
2NaHSO4⟶Na2S2O8+H2 {\displaystyle {\ce {2 NaHSO4 -> Na2S2O8 + H2}}}
Oxidation is conducted at a platinum anode.
In this way about 165,000 tons were produced in 2005.

The standard redox potential of sodium persulfate into hydrogen sulfate is 2.1 V, which is higher than that of hydrogen peroxide (1.8 V) but lower than ozone (2.2 V).
The sulfate radical formed in situ has a standard electrode potential of 2.7 V.

However, there are a few drawbacks in utilizing platinum anodes to produce the salts; the manufacturing process is inefficient due to oxygen evolution and the product could contain contaminants coming from platinum corrosion (mainly due to extremely oxidizing nature of the sulfate radical).
Thus, boron-doped diamond electrodes have been proposed as alternatives to the conventional platinum electrodes.

STRUCTURE OF SODIUM PEROXODISULFATE:
The sodium and potassium salts adopt very similar structures in the solid state, according to X-ray crystallography. In the sodium salt, the O-O distance is 1.476 Å.
The sulfate groups are tetrahedral, with three short S-O distances near 1.44 and one long S-O bond at 1.64 Å.

APPLICATIONS OF SODIUM PEROXODISULFATE:
Sodium peroxodisulfate is mainly used as a radical initiator for emulsion polymerization reactions for styrene based polymers such as Acrylonitrile butadiene styrene.
Also applicable for accelerated curing of low formaldehyde adhesives.

Sodium peroxydisulfate is used as a radical initiator for emulsion polymerization reactions like acrylonitrile butadiene styrene, detergent component, soil conditioner and soil remediation.
Sodium peroxodisulfate is also used for curing of formaldehyde adhesives.
Sodium peroxodisulfate acts as a bleaching agent and in the production of dyestuffs.

Sodium peroxodisulfate finds application in zinc and printed circuit boards and considered to be a replacement for ammonium persulfate in etching mixtures.
Further, Sodium peroxodisulfate is used in the preparation of diapocynin from apocynin.
Sodium peroxodisulfate plays a role in the conversion of phenols to para-diphenols in alkaline solution and of arylamines to aminophenols.
Sodium peroxodisulfate is actively involved in the Elbs persulfate oxidation and the Boyland-Sims oxidation reactions as an oxidizing agent.



OTHER USES OF SODIUM PEROXODISULFATE:
Sodium peroxodisulfate is a bleach, both standalone (particularly in hair cosmetics) and as a detergent component.
Sodium peroxodisulfate is a replacement for ammonium persulfate in etching mixtures for zinc and printed circuit boards, and is used for pickling of copper and some other metals.

Sodium peroxodisulfate is also used as a soil conditioner and for soil and groundwater remediation and in manufacture of dyestuffs, modification of starch, bleach activator, desizing agent for oxidative desizing, etc.

Organic chemistry:
Sodium persulfate is a specialized oxidizing agent in chemistry, classically in the Elbs persulfate oxidation and the Boyland–Sims oxidation reactions.
Sodium peroxodisulfate is also used in radical reactions; for example in a synthesis of diapocynin from apocynin where iron(II) sulfate is the radical initiator.

Sodium peroxodisulfate is a strongly oxidizing chemical used as a bleaching and oxidizing agent.
Persulfate oxidation mechanisms are effective in degrading many volatile oxidizing chemicals (VOCs) including chlorinated ethenes (CEs), BTEXs and trichloroethanes.
Sodium peroxodisulfate is used as a promoter for polymerization reactions.
Sodium peroxodisulfate has also been used as a chemical oxidant to treat laboratory slurry reactors for the accumulation of surfactants.




SAFETY INFORMATION ABOUT SODIUM PEROXODISULFATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



SYNONYMS OF SODIUM PEROXODISULFATE:
MeSH Entry Terms:
sodium peroxodisulfate
sodium persulfate
Sodium persulfate
7775-27-1
Sodium peroxydisulfate
Sodium peroxodisulfate
Peroxydisulfuric acid, disodium salt
disodium;sulfonatooxy sulfate
J49FYF16JE
DSSTox_CID_9698
Disodium peroxodisulphate
DSSTox_RID_78813
DSSTox_GSID_29698
Peroxydisulfuric acid (((HO)S(O)2)2O2), sodium salt (1:2)
sodium persulphate
CAS-7775-27-1
Persulfate de sodium
Persulfate de sodium [French]
Sodium peroxydisulphate
Disodium peroxydisulfate
EINECS 231-892-1
MFCD00003501
UN1505
UNII-J49FYF16JE
Peroxydisulfuric acid (((HO)S(O)2)2O2), disodium salt
sodium peroxidisulfate
ORISTAR SP
Sodium peroxy disulfate
Na2S2O8
EC 231-892-1
SODIUM PERSULFATE [MI]
DTXSID4029698
SODIUM PERSULFATE [INCI]
SODIUM PERSULFATE [VANDF]
Tox21_201326
Tox21_303592
SODIUM PERSULFATE (NA2S2O8)
AKOS025244086
NCGC00257410-01
NCGC00258878-01
Sodium persulfate [UN1505] [Oxidizer]
disodium [(sulfonatoperoxy)sulfonyl]oxidanide
FT-0698963
Q419438

DESCRIPTION:
Sodium Peroxydisulfate (Sodium Persulfate) is the inorganic compound with the formula Na2S2O8.
Sodium Peroxydisulfate (Sodium Persulfate) is the sodium salt of peroxydisulfuric acid, H2S2O8, an oxidizing agent.
Sodium Peroxydisulfate (Sodium Persulfate) is a white solid that dissolves in water.

CAS Number: 7775-27-1
EC Number: 231-892-1
Molecular Formula: Na2S2O8


Sodium Peroxydisulfate (Sodium Persulfate) is almost non-hygroscopic and has good shelf-life.
Sodium Peroxydisulfate (Sodium Persulfate) appears as a white crystalline solid.
Sodium Peroxydisulfate (Sodium Persulfate) is Very irritating to skin and eyes.

Sodium Peroxydisulfate (Sodium Persulfate) May be toxic by skin absorption.
Sodium Peroxydisulfate (Sodium Persulfate) is Used as a bleaching agent.

Sodium Peroxydisulfate (Sodium Persulfate) is a strongly oxidizing chemical used as a bleaching and oxidizing agent.
Persulfate oxidation mechanisms are effective in degrading many volatile oxidizing chemicals (VOCs) including chlorinated ethenes (CEs), BTEXs and trichloroethanes.
Sodium Peroxydisulfate (Sodium Persulfate) is used as a promoter for polymerization reactions.
Sodium Peroxydisulfate (Sodium Persulfate) has also been used as a chemical oxidant to treat laboratory slurry reactors for the accumulation of surfactants.


Sodium Peroxydisulfate (Sodium Persulfate) is used as a radical initiator for emulsion polymerization reactions like acrylonitrile butadiene styrene, detergent component, soil conditioner and soil remediation.
Sodium Peroxydisulfate (Sodium Persulfate) is also used for curing of formaldehyde adhesives.
Sodium Peroxydisulfate (Sodium Persulfate) acts as a bleaching agent and in the production of dyestuffs.

Sodium Peroxydisulfate (Sodium Persulfate) finds application in zinc and printed circuit boards and considered to be a replacement for ammonium persulfate in etching mixtures.
Further, Sodium Peroxydisulfate (Sodium Persulfate) is used in the preparation of diapocynin from apocynin.

Sodium Peroxydisulfate (Sodium Persulfate) plays a role in the conversion of phenols to para-diphenols in alkaline solution and of arylamines to aminophenols.
Sodium Peroxydisulfate (Sodium Persulfate) is actively involved in the Elbs persulfate oxidation and the Boyland-Sims oxidation reactions as an oxidizing agent.


Sodium Peroxydisulfate (Sodium Persulfate) is a white crystalline salt that is commonly used as an oxidizing agent in various chemical reactions.
Sodium Peroxydisulfate (Sodium Persulfate) is also known as sodium peroxodisulfate or simply "SPS."
Sodium Peroxydisulfate (Sodium Persulfate) has a molecular formula of Na2S2O8 and a molar mass of 238.13 g/mol.
Sodium Peroxydisulfate (Sodium Persulfate) is soluble in water and is commonly used in the production of polymers, detergents, and in various industrial applications.

Sodium Peroxydisulfate (Sodium Persulfate) exists as colorless crystals or a white, crystalline powder.
Sodium Peroxydisulfate (Sodium Persulfate) has a melting point of 150 °C and is slightly soluble in ethanol and acetone.
Sodium Peroxydisulfate (Sodium Persulfate) is extremely stable at room temperature but can decompose at higher temperatures or when exposed to ultraviolet light to release oxygen gas.
Sodium Peroxydisulfate (Sodium Persulfate) is a strong oxidizing agent and can react with organic compounds to release heat and gases.
SYNTHESIS AND CHARACTERIZATION OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
Sodium Peroxydisulfate (Sodium Persulfate) is produced by electrolysis of an aqueous solution of sodium sulfate.
The reaction produces hydrogen gas and persulfate ions, which then form sodium persulfate.
Sodium Peroxydisulfate (Sodium Persulfate) can also be synthesized through reaction between hydrogen peroxide and sodium metabisulfite.

The resulting solution is then treated with ammonia to obtain pure sodium persulfate.
Characterization of Sodium Peroxydisulfate (Sodium Persulfate) can be performed with several analytical techniques, including X-ray diffraction, Fourier transform infrared spectroscopy, and electron microscopy.
These methods help to determine the crystal structure, composition, and morphology of the compound.

ANALYTICAL METHODS OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
Sodium Peroxydisulfate (Sodium Persulfate) can be analyzed using several methods, including chemical analysis, spectrophotometric analysis, and chromatography.
These techniques are used to determine the purity, concentration, and properties of the compound.


BIOLOGICAL PROPERTIES OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
Sodium Peroxydisulfate (Sodium Persulfate) is generally considered safe to use in scientific experiments.
However, some studies have suggested that Sodium Peroxydisulfate (Sodium Persulfate) may have harmful effects on aquatic organisms and may cause skin or eye irritation in humans.
More research is needed to understand the potential biological effects of sodium persulfate.


PRODUCTION OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
The salt is prepared by the electrolytic oxidation of sodium bisulfate:
2NaHSO4⟶Na2S2O8+H2
Oxidation is conducted at a platinum anode.
In this way about 165,000 tons were produced in 2005.

The standard redox potential of sodium persulfate into hydrogen sulfate is 2.1 V, which is higher than that of hydrogen peroxide (1.8 V) but lower than ozone (2.2 V).
The sulfate radical formed in situ has a standard electrode potential of 2.7 V.

However, there are a few drawbacks in utilizing platinum anodes to produce the salts; the manufacturing process is inefficient due to oxygen evolution and the product could contain contaminants coming from platinum corrosion (mainly due to extremely oxidizing nature of the sulfate radical).
Thus, boron-doped diamond electrodes have been proposed as alternatives to the conventional platinum electrodes.

STRUCTURE OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
The sodium and potassium salts adopt very similar structures in the solid state, according to X-ray crystallography.
In the sodium salt, the O-O distance is 1.476 Å.
The sulfate groups are tetrahedral, with three short S-O distances near 1.44 and one long S-O bond at 1.64 Å.


PREPARATION METHOD OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
1. The electrolytic oxidation of the aqueous solution of ammonium sulfate is to obtain ammonium persulfate, and then metathesis reaction with sodium hydroxide, after the expulsion of the ammonia by-product, and then concentrated under reduced pressure, crystallization, drying, to obtain sodium sulfate.
(NH4) 2S2O8 + 2NaOH → Na2S2O8 + 2NH3 + 2H2O.
2. Dithionic acid can be prepared by electrolysis of cold sulfuric acid won, which reacts with alkali and then obtain sodium sulfate.
2HSO4--2e → H2S2O8
H2S2O8 + 2NaOH → Na2S2O8 + 2H2O.






APPLICATIONS OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
Sodium Peroxydisulfate (Sodium Persulfate)is mainly used as a radical initiator for emulsion polymerization reactions for styrene based polymers such as Acrylonitrile butadiene styrene.
Also applicable for accelerated curing of low formaldehyde adhesives.
Environmental remediation agents: contaminated soil remediation, water treatment (wastewater purification); Waste gas treatment, oxidative degradation of harmful substances (e.g. mercury).

Polymerization: the initiator of latex or acrylic monomer polymerization solution, vinyl acetate, vinyl chloride and other products, but also styrene, acrylonitrile, butadiene and other colloidal copolymerization initiator.

Metal treatment: cleaning and pickling of metal surfaces (e.g., in semiconductor manufacturing: cleaning and etching of printed circuits). Activation of copper and aluminum surfaces.
Used to speed up the processing of low concentration formalin adhesive.
A modifier used in the production of starch and used as a desorption agent in the production of adhesives and coatings

Cosmetics: essential ingredient in bleaching formulations.

Textiles: Depulsing agents and bleaches - especially for low temperature bleaching.

Hair dye: It is one of the basic components of hair dye and plays a decolorizing role.

Others: chemical synthesis; Disinfectant; Water treatment, purification and disinfection; Waste gas treatment; Oxidative degradation of hazardous substances (e.g. mercury); Paper (low temperature bleaching especially in pulping); Water-reducing agent for mixing suspected soil; In petroleum exploitation, used for fracturing fluid of oil well broken glue agent.








OTHER USES OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
Sodium Peroxydisulfate (Sodium Persulfate)is a bleach, both standalone (particularly in hair cosmetics) and as a detergent component.
Sodium Peroxydisulfate (Sodium Persulfate) is a replacement for ammonium persulfate in etching mixtures for zinc and printed circuit boards, and is used for pickling of copper and some other metals.

Sodium Peroxydisulfate (Sodium Persulfate) is also used as a soil conditioner and for soil and groundwater remediation and in manufacture of dyestuffs, modification of starch, bleach activator, desizing agent for oxidative desizing, etc.

Sodium Peroxydisulfate (Sodium Persulfate) is used as a bleach, both standalone (particularly in hair cosmetics) and as a detergent component.
Sodium Peroxydisulfate (Sodium Persulfate) is a replacement for ammonium persulfate in etching mixtures for zinc and printed circuit boards, and is used for pickling of copper and some other metals.
Sodium Peroxydisulfate (Sodium Persulfate) is a source of free radicals, making it useful as an initiator for e.g. emulsion polymerization reactions and for accelerated curing of low formaldehyde adhesives.

Sodium Peroxydisulfate (Sodium Persulfate) is also used as a soil conditioner and in manufacture of dyestuffs, modification of starch, bleach activator, desizing agent for oxidative desizing, etc.
For waste processing in the photographic industry, used as a soft metal surface corrosion agents of the printed circuit board and textile desizing agents, sulfur dyes colorformer.

Sodium Peroxydisulfate (Sodium Persulfate) is used as a radical initiator for emulsion polymerization reactions like acrylonitrile butadiene styrene, detergent component, soil conditioner and soil remediation. It is also used for curing of formaldehyde adhesives.
Sodium Peroxydisulfate (Sodium Persulfate) acts as a bleaching agent and in the production of dyestuffs.
Sodium Peroxydisulfate (Sodium Persulfate) finds application in zinc and printed circuit boards and considered to be a replacement for ammonium persulfate in etching mixtures.

Further, Sodium Peroxydisulfate (Sodium Persulfate) is used in the preparation of diapocynin from apocynin.
Sodium Peroxydisulfate (Sodium Persulfate) plays a role in the conversion of phenols to para-diphenols in alkaline solution and of arylamines to aminophenols.
Sodium Peroxydisulfate (Sodium Persulfate) is actively involved in the Elbs persulfate oxidation and the Boyland-Sims oxidation reactions as an oxidizing agent.







ORGANIC CHEMISTRY
Sodium Peroxydisulfate (Sodium Persulfate) is a specialized oxidizing agent in chemistry, classically in the Elbs persulfate oxidation and the Boyland–Sims oxidation reactions.
Sodium Peroxydisulfate (Sodium Persulfate) is also used in radical reactions; for example in a synthesis of diapocynin from apocynin where iron(II) sulfate is the radical initiator



CHEMICAL AND PHYSICAL PROPERTIES OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
Chemical formula Na2S2O8
Molar mass 238.10 g/mol
Appearance White powder
Density 2.601 g/cm3
Melting point 180 °C (356 °F; 453 K) decomposes
Solubility in water 55.6 g/100 ml (20 °C)
Molecular Weight
238.11 g/mol
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Rotatable Bond Count
1
Exact Mass
237.88299787 g/mol
Monoisotopic Mass
237.88299787 g/mol
Topological Polar Surface Area
150Ų
Heavy Atom Count
12
Formal Charge
0
Complexity
206
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Physical Form Crystalline
Quantity 1 kg
Assay Percent Range 98%
Solubility Information Soluble in water.
Formula Weight 238.1
Density 2.40 g/mL
Chemical Name or Material Sodium peroxydisulfate
CAS Number7775-27-1
Alternate CAS #Deleted CAS: 872981-99-2
Molecular FormulaNa₂O₈S₂
AppearanceWhite to Off-White Solid
Melting Point>300°C
Molecular Weight238.1
Storage-20°C, Hygroscopic
SolubilityWater (Slightly)
StabilityHygroscopic
CategoryResearch Tools; Materials;
Assay (iodometric) ≥ 99.0 %
Identity passes test
Chloride (Cl) ≤ 0.01 %
Heavy metals (as Pb) ≤ 0.003 %
NH₄ (Ammonium) ≤ 0.05 %
Cr (Chromium) ≤ 0.001 %
Cu (Copper) ≤ 0.001 %
Fe (Iron) ≤ 0.0005 %
Mn (Manganese) ≤ 0.0001 %
Pb (Lead) ≤ 0.001 %
Loss on drying (105 °C; 3 hours) ≤ 0.05 %
appearance
white crystal powder
ASSAY [Na2S2O8] ω/ %
≥99.0%
Fe ω/ %
≤0.001%
Mn ω/ %
≤0.0001%
chloride(CL) ω/ %
≤0.005%
AMMONIUM SALT [NH4] ω/ %
≤0.20%
MOISTURE ω/ %
≤0.10%
heavy metal (Pb) ) ω/ %
≤0.001%
ACTIVE OXYGEN
≥6.65%
PH(50g/L solution) ω/ %
3.5~5.5








SAFETY INFORMATION ABOUT SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product








SYNONYMS OF SODIUM PEROXYDISULFATE (SODIUM PERSULFATE):
sodium peroxodisulfate
sodium persulfate
Sodium persulfate
7775-27-1
Sodium peroxydisulfate
Sodium peroxodisulfate
Peroxydisulfuric acid, disodium salt
disodium;sulfonatooxy sulfate
J49FYF16JE
DTXSID4029698
DTXCID009698
Disodium peroxodisulphate
Peroxydisulfuric acid (((HO)S(O)2)2O2), sodium salt (1:2)
sodium persulphate
CAS-7775-27-1
Persulfate de sodium
Persulfate de sodium [French]
Sodium peroxydisulphate
Disodium peroxydisulfate
EINECS 231-892-1
MFCD00003501
UN1505
UNII-J49FYF16JE
Peroxydisulfuric acid (((HO)S(O)2)2O2), disodium salt
sodium peroxidisulfate
ORISTAR SP
Sodium peroxy disulfate
Na2S2O8
EC 231-892-1
SODIUM PERSULFATE [MI]
SODIUM PERSULFATE [INCI]
SODIUM PERSULFATE [VANDF]
CHQMHPLRPQMAMX-UHFFFAOYSA-L
Tox21_201326
Tox21_303592
SODIUM PERSULFATE (NA2S2O8)
AKOS025244086
NCGC00257410-01
NCGC00258878-01
Sodium persulfate [UN1505] [Oxidizer]
disodium [(sulfonatoperoxy)sulfonyl]oxidanide
FT-0698963
Q419438
Sodium persulfate [Wiki]
[(Sulfonatoperoxy)sulfonyl]oxydanide de disodium [French] [ACD/IUPAC Name]
231-892-1 [EINECS]
7775-27-1 [RN]
Dinatrium-[(sulfonatoperoxy)sulfonyl]oxidanid [German] [ACD/IUPAC Name]
Disodium [(sulfonatoperoxy)sulfonyl]oxidanide [ACD/IUPAC Name]
Disodium peroxodisulphate
J49FYF16JE
MFCD00003501
Persulfate de sodium [French]
SE0525000
Sodium peroxodisulfate
SODIUM PEROXYDISULFATE
DISODIUM PEROXODISULFATE
disodium sulfato sulfate
disodium sulfonatooxy sulfate
disodium;sulfonatooxy sulfate
EINECS 231-892-1
Peroxydisulfuric acid, disodium salt
Persulfate de sodium [French]
persulfato de sódio [Portuguese]
Sodium peroxidisulfate
sodium peroxydisulphate
Sodium persulfate [UN1505] [Oxidizer]
Sodium persulfate, Peroxydisulfuric acid disodium salt
Sodium persulphate
sodiumpersulfate
UNII:J49FYF16JE
UNII-J49FYF16JE