Water Treatment, Metal and Mining Chemicals

HYDRARGILLITE
Hydrargillite is found in nature as the mineral gibbsite (also known as hydrargillite) and Hydrargillite three much rarer polymorphs: bayerite, doyleite, and nordstrandite.
Hydrargillite is amphoteric, i.e., Hydrargillite has both basic and acidic properties.
Hydrargillite is a halogen-free, environmentally friendly flame retardant and smoke suppressant filler for plastics and rubber.

CAS Number: 21645-51-2
EC Number: 244-492-7
Chemical Formula: Al(OH)3
Molar Mass: 78.003 g·mol−1

Aluminium trihydrate, Aluminum, trihydrate, DTXSID20421935, MXRIRQGCELJRSN-UHFFFAOYSA-N, aluminum;trihydroxide, Dried aluminum hydroxide gel, Aluminium hydroxide gel, dried, aluminium trihydroxide, aluminum hyroxide, Hydroxyde d' aluminium, Dried aluminium hydroxide, Aluminium hydroxide, dried, Aluminum hydroxide gel, dried, CHEMBL1200706, DTXSID2036405, NIOSH/BD0708000, Di-mu-hydroxytetrahydroxydialuminum, AF-260, AKOS015904617, Aluminum, di-mu-hydroxytetrahydroxydi-, DB06723, BD07080000, Aluminium trihydrate [ACD/IUPAC Name], Aluminium, trihydrate [French] [ACD/IUPAC Name], Aluminiumtrihydrat [German] [ACD/IUPAC Name], 106152-09-4 [RN], 12252-70-9 [RN], 128083-27-2 [RN], 1302-29-0 [RN], 13783-16-9 [RN], 14762-49-3 [RN], 151393-94-1 [RN], 159704-77-5 [RN], 21645-51-2 [RN], 51330-22-4 [RN], 8012-63-3 [RN], 8064-00-4 [RN], AC 714KC, AKP-DA, Al(OH)3, Alcoa A 325, Alcoa AS 301, Alcoa C 30BF, Alcoa C 31, Alcoa C 33, Alcoa C 330, Alcoa C 331, Alcoa C 333, Alcoa C 385, Alcoa H 65, Alhydrogel [Wiki], Alolt 8, ALterna GEL [Trade name], ALternaGEL, Alu-Cap, Alugel, Alugelibye, Alumigel, Alumina trihydrate, Aluminic acid (H3AlO3), Aluminium hydroxide [Wiki], aluminium(3+) hydroxide, aluminium(III) hydroxide, Aluminiumhydroxid, ALUMINUM HYDROXIDE [USP], Aluminum hydroxide (Al(OH)3), Aluminum Hydroxide Gel, Aluminum hydroxide, dried [JAN], Aluminum oxide trihydrate, Aluminum trihydroxide, Aluminum(III) hydroxide, Alusal, Amberol ST 140F, Amorphous alumina, Amphogel, Amphojel, Antipollon HT, Apyral, Apyral 120, Apyral 120VAW, Apyral 15, Apyral 2, Apyral 24, Apyral 25, Apyral 4, Apyral 40, Apyral 60, Apyral 8, Apyral 90, Apyral B, Arthritis Pain Formula Maximum Strength, Ascriptin, BACO AF 260, Boehmite, British aluminum AF 260, C 31C, C 31F, C 4D, C-31-F, Calcitrel, Calmogastrin, Camalox, Dialume [Trade name], Di-Gel Liquid, Gelusil, Gibbsite (Al(OH)3), Higilite, Higilite H 31S, Higilite H 32, Higilite H 42, Hychol 705, Hydrafil, Hydral 705, Hydral 710, Hydrated Alumina, Hydrated aluminum oxide, Kudrox, Liquigel, Maalox [Wiki], Maalox HRF, Maalox Plus, Martinal, Martinal A, Martinal A/S, Martinal F-A, Mylanta [Wiki], P 30BF, Reheis F 1000, Simeco Suspension, Tricreamalate, Trihydrated alumina, trihydroxidoaluminium, Trihydroxyaluminum, Trisogel, WinGel

Hydrargillite is initially derived from bauxite ore, before being refined into a fine white powder.
Hydrargillite (also known as ATH and aluminium trihydroxide, chemical formula Al (OH)3) is initially derived from bauxite ore, before being refined into a fine white powder.

Annual production of Hydrargillite is around 100 million tons which is nearly all produced through the Bayer process.
The Bayer process dissolves bauxite (Aluminium Ore) in sodium hydroxide at elevated temperatures.

Hydrargillite is then separated from the solids that remain after the heating process.
The solids remaining after the Hydrargillite is removed is highly toxic and presents environmental issues.

Hydrargillite are available in different uncoated and coated grades, with average particle size varying from 2 microns to 80 microns as per application.
Hydrargillite is a common primary ingredient present in most solid surface material and accounts for as much as 70% of the total product.

Hydrargillite is used as a filler for epoxy, urethane, or polyester resins, where fire retardant properties or increased thermal conductivity are required.
Hydrargillite is white in color.

Hydrargillite is a flame retardant and smoke suppressant.
Hydrargillite thermodynamic properties, endothermic dehydration cools the plastic 6 rubber parts and dilutes the combustible gases with water vapours that is generated in case of fire.

Hydrargillite is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 000 to < 10 000 000 tonnes per annum.
Hydrargillite is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Hydrargillite is a halogen-free, environmentally friendly flame retardant and smoke suppressant filler for plastics and rubber.
Hydrargillite is suitable for a broad range of applications including solid surface, composites and electrical insulation.

Hydrargillite is a white, translucent powder that is also called aluminum hydroxide.
Hydrargillite is obtained from Bauxite.

When Hydrargillite is strongly heated, Hydrargillite will convert to Aluminum oxide with the release of water.
Hydrargillite is used as a base in the preparation of transparent lake pigments.

Hydrargillite is also used as an inert filler in paints and tends to increase the transparency of colors when dispersed in oils.
Hydrargillite is used commercially as a paper coating, flame retardant, water repellant, and as a filler in glass, ceramics, inks, detergents, cosmetics, and plastics.

Hydrargillite is found in nature as the mineral gibbsite (also known as Aluminium trihydrate) and Hydrargillite three much rarer polymorphs: bayerite, doyleite, and nordstrandite.
Hydrargillite is amphoteric, i.e., Hydrargillite has both basic and acidic properties.

Closely related are aluminium oxide hydroxide, AlO(OH), and aluminium oxide or alumina (Al2O3), the latter of which is also amphoteric.
These compounds together are the major components of the aluminium ore bauxite.
Hydrargillite also forms a gelatinous precipitate in water.

Hydrargillite is a non-halogen fire retardant and smoke suppressant.
Hydrargillite is a major mineral fire retardant being the largest selling fire retardant additive in the world.

Hydrargillite is used commercially as a paper coating, flame retardant, water repellant, and as a filler in glass, ceramics, inks, detergents, cosmetics, and plastics.
When strongly heated, Hydrargillite decomposes into aluminium oxide with release of water following an endothermic reaction.

Hydrargillite (ATH or hydrated alumina) is a non-toxic, non-corrosive, flame retardant and smoke suppressant utilized in elastomeric applications.
Hydrargillite is the most frequently used flame retardant in the world.

Hydrargillite is a very effective flame retardant due to Hydrargillite thermodynamic properties which absorb heat and release water vapor.
Hydrargillite releases its 35% water of crystallization as water vapor when heated above 205°C.

The resulting endothermic reaction cools Hydrargillite below flash point, reducing the risk of fire and acts as a vapor barrier to prevent oxygen from reaching the flame.
Typical loadings vary from 20 phr to 150 phr.
Because many polymers like polyethylene and polypropylene process above 200°C, these polyolefins should use magnesium hydroxide as a flame retardant filler since Hydrargillite water of hydration releases at approximately 325°C.

Hydrargillites are obtained by digestion of bauxite throughout the Bayer process.

Hydrargillite starts to remove constitution water above 180°C
Water removal cools the surface and eliminates entry of oxygen, which confers flame retardant properties and smoke suppressant.
Accordingly Hydrargillite is a necessary raw material for products like rubber, polyurethane, polyester, silicone, thermoplastic, cables, etc. with fire retardant properties.

Hydrargillite has a number of common names used throughout the chemical industry which include: Hydrate Alumina, Alumina Hydrate, Aluminium Tri Hydroxide, ATH, Aluminium Hydrate and Aluminium Hydroxide.

Hydrargillite is a white, odorless, powdery, solid substance.
Hydrargillite demonstrates a very low solubility in water but is considered to be amphoteric, meaning Hydrargillite will dissolve in both acids or a strong alkali.

The most common use of Hydrargillite is for the production of aluminum metal.
Hydrargillite is also used as a flame retardant and smoke suppressant filler in polymers such as rubber products and carpet backing.

Hydrargillite is a white filling material that provides flame retardant and self-extinguishing properties for polyester resins and gelcoats.
Hydrargillite exposes water molecules within the body at high temperatures to reduce flame spread and smoke formation.
Hydrargillite is used in GRP pipe applications, in acrylic applications and in other multicomponent applications.

Aluminum trihydrate (also known as aluminum hydrate, alumina hydrate, aluminum hydroxide, or ATH) is a filler, extender pigment, and bodying agent in oil- and water-borne paint that does not greatly affect the color of the paint.
This is an 8-micron median particle size extender that is a white to tan colored powder and can be added to paint to impart transparency to the paint film.

Hydrargillite is the most widely used flame retardant in commercial coatings due to Hydrargillite versatility and low cost.
Hydrargillite can be used in a wide range of paint binders at processing temperatures below 220°C.

Hydrargillite is non-toxic, halogen-free, chemically inert, and has low abrasiveness.
Additional benefits are acid resistance and smoke suppression.

At about 220°C, Hydrargillite begins to decompose endothermically releasing approximately 35% of Hydrargillite weight as water vapor.

AI2O3•3H2O + HEAT —–> AI2O3 + 3 H2O

Hydrargillite acts as a heat sink thereby retarding pyrolysis and reducing the burning rate.
The water vapor released has an added effect of diluting combustion gases and toxic fumes.

Hydrargillite is the hydrated oxide of aluminium.
Aluminium hydrate is separated from bauxite ore using the Bayer process, with average particle size ranging from 80-100 micron.

The block crystals of alumina hydrate impart good chemical reactivity.
Alumina hydrate can react with a base as well as an acid, and finds use in many applications as raw material.

After drying, alumina hydrate is ground using mechanical mills and ceramic lined ball mills to obtain finer particle sizes.
Hindalco manufactures ground hydrate with different particle size (5-15 micron) distribution.
Surface-treated fine hydrate as well as super-ground fine hydrate (1-2.5 micron) are also available.

Hydrargillite obtained in the Bayer process, is calcined at temperature above 1200°C and up to 1600°C to manufacture special grade alumina.
During calcinations, alumina hydrate crystals lose bound moisture and recrystallise to form alumina crystals.

The particle size of alumina remains at 85-100 micron.
Special alumina contains predominantly alpha phase.
The degree of calcination is a measure of the hardness of alumina – soft to hard.

Coarse alumina is classified based on the soda (Na2O) content:
Low soda alumina - Na2O <0.1%
Medium soda alumina - 0.1% < Na2O <0.2%
Normal Soda alumina - 0.20% < Na2O < 0.45%

Calcined alumina is ground in fluid energy mills or ceramic lined ball mills to meet the desired particle size required by the customers.
Hindalco manufactures fine alumina with varying particle size (0.5 to 8 micron) and distribution.
Low soda, medium soda and normal soda type are available in fine alumina also.

The global Hydrargillite market size was valued at USD 1.5 billion in 2020 and is projected to reach USD 1.9 billion by 2025, growing at a cagr 5.5% from 2020 to 2025.
The major drivers for the market include the rising consumer demand for Hydrargillite in different applications and enduse industries, such as flame retardants, and paints & coatings.
However, the substitutes present in the market, for instance, magnesium hydroxide, can restrain the market growth.

Covid-19 Impact On The Global Hydrargillite Market:
The global Hydrargillite market is expected to witness a moderate decrease in Hydrargillite growth rate in 2020-2021, as the Hydrargillite industry witness a significant decline in Hydrargillite production.
Hydrargillite has affected the market for Hydrargillite manufacturers catering to the glass and rubber industries, which were not considered essential.

Moreover, most of the global companies operating in this market are based in Asia Pacific, the US, and European countries, which are adversely affected by the pandemic.
These companies having their manufacturing units in China and other Asian countries are also severely affected.
Therefore, disruptions in the supply chain have resulted in hampering production units due to a lack of raw materials and workforce.

Hydrargillite Market Dynamics:

Driver: Increasing demand for non-halogenated flame retardants:
The growing number of residential and commercial establishments has increased the possibilities of explosions and fire-related accidents.
Therefore, several countries across North America and Europe have mandated stringent fire safety regulations and protocols.

This has led to the increased use of flame retardants in buildings to meet these government regulations.
The major application of flame retardants is in electric wire insulation in building & construction, and transportation.

Flame retardants are used in circuit boards, electronic casing, and cables & wire systems.
Stringent fire safety standards to reduce the spread of fires in residential and commercial buildings are driving the demand for halogen-free flame retardants.

Opportunities:
Use of Hydrargillite in water treatment plants Hydrargillite (alum) is the most common coagulant used in water and wastewater treatment.
The main purpose of using alum in these applications is to improve the settling of suspended solids and color removal.

Alum is also used to remove phosphate from wastewater treatment effluent.
Thus, the growing urbanization in emerging economies, such as China and India, is expected to fuel the demand for water treatment plants in residential areas.

Nevertheless, many people still lack access to safe water and suffer from preventable water-borne microbial diseases leading to the increased demand for wastewater treatment plants.
Thus, the use of aluminum hydroxide in water treatment plants in residential areas is expected to act as an opportunity for the growth of the Hydrargillite market across the globe.

Challenges:

Environmental issues related to alumina production:
Alumina production leads to bauxite residue, also known as red mud.
The disposal of bauxite residue/red mud is a challenge due to relatively large volumes, occupying land areas, and the alkalinity of the residue and the run-off water.

Only a very small proportion of the bauxite residue produced are re-used in any way.
Although the residue has a number of characteristics of environmental concern, the most immediate and apparent barrier to remediation and utilization is Hydrargillite high alkalinity and sodicity.

The high pH of the bauxite residue is a problem from both a health and safety point-of-view.
This can pose a challenge for the Hydrargillite market.

Applications of Hydrargillite:
Over 90% of all Hydrargillite produced is converted to Aluminium Oxide (alumina) that is used to manufacture aluminum.
As a flame retardant, Hydrargillite is chemically added to a polymer molecule or blended in with a polymer to suppress and reduce the spreading of a flame through a plastic.
Hydrargillite is also used as an antacid that can be ingested in order to buffer the pH within the stomach.

Hydrargillite is the hydrated oxide of aluminium.
Hydrargillite is separated from ore bauxite using Bayer process with average particle size ranging from 80-100 micron.

The blocky crystals of Hydrargillite impart good reactivity.
Hydrargillite can react with a base as well as an acid and finds many applications as raw material.

Hydrargillite is used in the manufacture of many inorganic chemicals like:
Non- ferric alum
Poly aluminium chloride
Aluminium fluoride
Sodium aluminate
Catalysts
Glass
Hydrargillite gel
Alumina hydrate is available in wet as well as dry form.

Fine hydrate:
Hydrargillite contain 3 molecules of water.
On exposure to heat above 220°C, alumina hydrate decomposes into aluminium oxide (alumina) and water.

This irreversible, endothermic reaction process makes alumina hydrate an effective flame retardant.
Also, the smoke generated by decomposition is non-corrosive and non-poisonous.
Ground alumina hydrate is used as fire retardant filler in applications like polymer composites, cable compounds, solid surface counter tops, etc.

Uses of Hydrargillite:
Of the Common fillers used in Plastics, Rubber, FRP, SMC, DMC moulding and other polymers only Hydrargillite has flame retarding and smoke suppressing properties as well as being an economical resin extender.

Hydrargillite is used in polyester resins.
However with increased attention being given to smoke & toxic fume emissions, Hydrargillite has found large volume application in vinyl as a low smoke, non toxic replacement for antimony and in polyurethane, latex, neoprene foam system, Rubber, wire & Cable insulation, vinyl walls & flooring coverings and epoxies.

Hydrargillite acts as a flame retardant and smoke suppressor because of Hydrargillite thermodynamic properties.
Hydrargillite endothermic dehydration cools the plastic & Rubber parts and dilute with water vapour those combustible gases that do escape.
The latter is probably the main phenomenon associated with smoke suppression other excellent performance include electrical and track resistance.

Hydrargillite widely use in Paper Industries as a whitening agent in place of titanium dioxide.

Hydrargillite is also use in Paints Industries.
Hydrargillite can replace upto 25% of the Titanium dioxide pigment & therefore is an economical extender reducing production cost.

Fire retardant filler:
Hydrargillite also finds use as a fire retardant filler for polymer applications.
Hydrargillite is selected for these applications because Hydrargillite is colorless (like most polymers), inexpensive, and has good fire retardant properties.

Magnesium hydroxide and mixtures of huntite and hydromagnesite are used similarly.
Hydrargillite decomposes at about 180 °C (356 °F), absorbing a considerable amount of heat in the process and giving off water vapour.
In addition to behaving as a fire retardant, Hydrargillite is very effective as a smoke suppressant in a wide range of polymers, most especially in polyesters, acrylics, ethylene vinyl acetate, epoxies, polyvinyl chloride (PVC) and rubber.

Precursor to Al compounds:
Hydrargillite is a feedstock for the manufacture of other aluminium compounds: calcined aluminas, aluminium sulfate, polyaluminium chloride, aluminium chloride, zeolites, sodium aluminate, activated alumina, and aluminium nitrate.

Freshly precipitated Hydrargillite forms gels, which are the basis for the application of aluminium salts as flocculants in water purification.
This gel crystallizes with time.

Hydrargillite gels can be dehydrated (e.g. using water-miscible non-aqueous solvents like ethanol) to form an amorphous Hydrargillite powder, which is readily soluble in acids.
Heating converts Hydrargillite to activated aluminas, which are used as desiccants, adsorbent in gas purification, and catalyst supports.

Pharmaceutical:
Under the generic name "algeldrate", Hydrargillite is used as an antacid in humans and animals (mainly cats and dogs).
Hydrargillite is preferred over other alternatives such as sodium bicarbonate because Al(OH)3, being insoluble, does not increase the pH of stomach above 7 and hence, does not trigger secretion of excess acid by the stomach.

Brand names include Alu-Cap, Aludrox, Gaviscon or Pepsamar.
Hydrargillite reacts with excess acid in the stomach, reducing the acidity of the stomach content, which may relieve the symptoms of ulcers, heartburn or dyspepsia.

Such products can cause constipation, because the aluminium ions inhibit the contractions of smooth muscle cells in the gastrointestinal tract, slowing peristalsis and lengthening the time needed for stool to pass through the colon.
Some such products are formulated to minimize such effects through the inclusion of equal concentrations of magnesium hydroxide or magnesium carbonate, which have counterbalancing laxative effects.

Hydrargillite is also used to control hyperphosphatemia (elevated phosphate, or phosphorus, levels in the blood) in people and animals suffering from kidney failure.
Normally, the kidneys filter excess phosphate out from the blood, but kidney failure can cause phosphate to accumulate.
The aluminium salt, when ingested, binds to phosphate in the intestines and reduce the amount of phosphorus that can be absorbed.

Precipitated Hydrargillite is included as an adjuvant in some vaccines (e.g. anthrax vaccine).
One of the well-known brands of Hydrargillite adjuvant is Alhydrogel, made by Brenntag Biosector.

Since Hydrargillite absorbs protein well, Hydrargillite also functions to stabilize vaccines by preventing the proteins in the vaccine from precipitating or sticking to the walls of the container during storage.
Hydrargillite is sometimes called "alum", a term generally reserved for one of several sulfates.

Vaccine formulations containing Hydrargillite stimulate the immune system by inducing the release of uric acid, an immunological danger signal.
This strongly attracts certain types of monocytes which differentiate into dendritic cells.

The dendritic cells pick up the antigen, carry Hydrargillite to lymph nodes, and stimulate T cells and B cells.
Hydrargillite appears to contribute to induction of a good Th2 response, so is useful for immunizing against pathogens that are blocked by antibodies.
However, Hydrargillite has little capacity to stimulate cellular (Th1) immune responses, important for protection against many pathogens, nor is Hydrargillite useful when the antigen is peptide-based.

Hydrargillite is used in various industries as:
Hydrargillite is used as a raw material in the production of Aluminium chemicals
Hydrargillite is used as a raw material in the manufacture of glass and glazes

Hydrargillite is used as a raw material in catalyst production
Hydrargillite is used as a flame retardant and smoke suppressant filler in plastics (for example: Cables, rubber products and carpet backing)

Hydrargillite is used as a raw material for fertilizers, and fiber cement board products
Hydrargillite is used as an extender and a bodying agent in paper, solvent- and water-borne paints, UV-curable coatings, inks, and adhesives

Hydrargillite is used as a polishing and cleansing agent Mould wash and separating agent
Hydrargillite is used as a filler of cast polymer products such as onyx and solid surfaces

Uses at industrial sites:
Hydrargillite is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and washing & cleaning products.
Hydrargillite has an industrial use resulting in manufacture of another substance (use of intermediates).

Hydrargillite is used in the following areas: mining, building & construction work and formulation of mixtures and/or re-packaging.
Hydrargillite is used for the manufacture of: chemicals, furniture, plastic products and rubber products.

Release to the environment of Hydrargillite can occur from industrial use: in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), formulation of mixtures, manufacturing of Hydrargillite and in processing aids at industrial sites.
Other release to the environment of Hydrargillite is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).

Consumer Uses:
Hydrargillite is used in the following products: cosmetics and personal care products, coating products, inks and toners, fillers, putties, plasters, modelling clay, pharmaceuticals, adhesives and sealants, washing & cleaning products, lubricants and greases and polishes and waxes.
Release to the environment of Hydrargillite can occur from industrial use: formulation of mixtures and formulation in materials.
Other release to the environment of Hydrargillite is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Widespread uses by professional workers:
Hydrargillite is used in the following products: inks and toners, coating products, fillers, putties, plasters, modelling clay, washing & cleaning products, adhesives and sealants, cosmetics and personal care products, lubricants and greases and polishes and waxes.
Hydrargillite is used in the following areas: building & construction work, printing and recorded media reproduction, formulation of mixtures and/or re-packaging and agriculture, forestry and fishing.

Hydrargillite is used for the manufacture of: textile, leather or fur and wood and wood products.
Other release to the environment of Hydrargillite is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Hydrargillite is characterised by:
High purity
High whiteness
Relatively low density (2.4g/cm3) compared to other mineral fillers (typically 2.7g/cm3)
Medium Mohs hardness of 3
Decomposition around 180oC, releasing water (making Hydrargillite an excellent halogen-free flame retardant)

Properties of Hydrargillite:
Hydrargillite is amphoteric.
In acid, Hydrargillite acts as a Brønsted–Lowry base.

Hydrargillite neutralizes the acid, yielding a salt:
3 HCl + Al(OH)3 → AlCl3 + 3 H2O

In bases, Hydrargillite acts as a Lewis acid by binding hydroxide ions:
Al(OH)3 + OH− → [Al(OH)4]−

Physical Properties:
Powdery substance
Odorless
Non-carcinogenic
Hydrargillite adds thermal properties that provide translucency and whiteness
Solid surface material
Non-smoking
Low-toxicity
Halogen-free
Flame retardant

Performance Benefits of Hydrargillite:
Flame retardant / smoke suppressant
Ultra-white / translucent
High purity – blush resistance
Faster gel time
Low viscosity / higher loadings
Higher mechanical properties

Production of Hydrargillite:
Virtually all the Hydrargillite used commercially is manufactured by the Bayer process which involves dissolving bauxite in sodium hydroxide at temperatures up to 270 °C (518 °F).
The waste solid, bauxite tailings, is removed and Hydrargillite is precipitated from the remaining solution of sodium aluminate.
This Hydrargillite can be converted to aluminium oxide or alumina by calcination.

The residue or bauxite tailings, which is mostly iron oxide, is highly caustic due to residual sodium hydroxide.
Hydrargillite was historically stored in lagoons; this led to the Ajka alumina plant accident in 2010 in Hungary, where a dam bursting led to the drowning of nine people.
An additional 122 sought treatment for chemical burns.

The mud contaminated 40 square kilometres (15 sq mi) of land and reached the Danube.
While the mud was considered non-toxic due to low levels of heavy metals, the associated slurry had a pH of 13.

Structure of Hydrargillite:
Al(OH)3 is built up of double layers of hydroxyl groups with aluminium ions occupying two-thirds of the octahedral holes between the two layers.
Four polymorphs are recognized.

All feature layers of octahedral Hydrargillite units, with hydrogen bonds between the layers.
The polymorphs differ in terms of the stacking of the layers.

All forms of Al(OH)3 crystals are hexagonal:
Gibbsite is also known as γ-Al(OH)3 or α-Al(OH)3
Bayerite is also known as α-Al(OH)3 or β-Hydrargillite
Nordstrandite is also known as Al(OH)3
Doyleite

Aluminium trihydrate, once thought to be Hydrargillite, is an aluminium phosphate.
Nonetheless, both gibbsite and Aluminium trihydrate refer to the same polymorphism of Hydrargillite, with gibbsite used most commonly in the United States and hydrargillite used more often in Europe.
Hydrargillite is named after the Greek words for water (hydra) and clay (argylles).

Safety of Hydrargillite:
In the 1960s and 1970s Hydrargillite was speculated that aluminium was related to various neurological disorders, including Alzheimer's disease.
Since then, multiple epidemiological studies have found no connection between exposure to environmental or swallowed aluminium and neurological disorders, though injected aluminium was not looked at in these studies.

Neural disorders were found in experiments on mice motivated by Gulf War illness (GWI).
Hydrargillite injected in doses equivalent to those administered to the United States military, showed increased reactive astrocytes, increased apoptosis of motor neurons and microglial proliferation within the spinal cord and cortex.

Identifiers of Hydrargillite:
CAS Number: 21645-51-2
ChEBI: CHEBI:33130
ChEMBL: ChEMBL1200706
ChemSpider: 8351587
DrugBank: DB06723
ECHA InfoCard: 100.040.433
KEGG: D02416
PubChem CID: 10176082
RTECS number: BD0940000
UNII: 5QB0T2IUN0
CompTox Dashboard (EPA): DTXSID2036405
InChI: InChI=1S/Al.3H2O/h;3*1H2/q+3;;;/p-3
Key: WNROFYMDJYEPJX-UHFFFAOYSA-K
A02AB02 (WHO) (algeldrate)
InChI=1/Al.3H2O/h;3*1H2/q+3;;;/p-3
Key: WNROFYMDJYEPJX-DFZHHIFOAJ
SMILES: [OH-].[OH-].[OH-].[Al+3]

CAS number: 21645-51-2
EC number: 244-492-7
Hill Formula: AlH₃O₃
Chemical formula: Al(OH)₃ * x H₂O
Molar Mass: 78 g/mol
HS Code: 2818 30 00
Quality Level: MQ200

Properties of Hydrargillite:
Chemical formula: Al(OH)3
Molar mass: 78.003 g·mol−1
Appearance: White amorphous powder
Density: 2.42 g/cm3, solid
Melting point: 300 °C (572 °F; 573 K)
Solubility in water: 0.0001 g/(100 mL)
Solubility product (Ksp): 3×10−34
Solubility: soluble in acids and alkalis
Acidity (pKa): >7
Isoelectric point: 7.7

Density: 2.42 g/cm3 (20 °C)
Melting Point: 300 °C Elimination of water of crystallisation
pH value: 8 - 9 (100 g/l, H₂O, 20 °C) (slurry)
Vapor pressure:
Molecular Weight: 81.028 g/mol
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 0
Exact Mass: 81.0132325 g/mol
Monoisotopic Mass: 81.0132325 g/mol
Topological Polar Surface Area: 3Ų
Heavy Atom Count: 4
Complexity: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 4
Compound Is Canonicalized: Yes

Thermochemistry of Hydrargillite:
Std enthalpy of formation (ΔfH⦵298): −1277 kJ·mol−1

Specifications of Hydrargillite:
Identity: conforms
Chloride (Cl): ≤ 0.01 %
Sulfate (SO₄): ≤ 0.05 %
Fe (Iron): ≤ 0.01 %
Na (Sodium): ≤ 0.3 %
Loss on ignition (700 °C): 30.0 - 35.0 %
Bulk density: about 90
Particle size (< 150 µm): about 90

Related compounds of Hydrargillite:
Boric acid
Gallium(III) hydroxide
Indium(III) hydroxide
Thallium(III) hydroxide
Scandium(III) hydroxide
Sodium oxide
Aluminium oxide hydroxide

Names of Hydrargillite:

Regulatory process names:
Aluminium hydroxide
aluminium hydroxide
Aluminum hydroxide, dried

IUPAC names:
Alumina hydrate
ALUMINA TRIHYDRATE
Alumina trihydrate
ALUMINIUM HYDROXIDE
Aluminium Hydroxide
Aluminium hydroxide
aluminium hydroxide
Aluminium Hydroxide
Aluminium hydroxide
aluminium hydroxide
Aluminium hydroxide, Alumina hydrate
Aluminium hydroxide_JS
Aluminium hydroxyde
aluminium trihydrate
Aluminium trihydrate
Aluminium trihydroxide
aluminium trihydroxide
aluminium(3+) ion trihydroxide
Aluminium(3+) trihydroxide
aluminium(3+) trihydroxide
aluminium(III) hydroxide
Aluminiumhydroxid
aluminuim hydroxide
ALUMINUM HYDROXIDE
Aluminum Hydroxide
Aluminum hydroxide
aluminum hydroxide
Aluminum hydroxide
Aluminum hydroxide (Al(OH)3)
Aluminum hydroxide (Al(OH)3)
Aluminum Trihydrate
Aluminum trihydrate
aluminum trihydrate
Aluminum trihydroxide
aluminum trihydroxide
ATH
Hydrate
Sulcabai

Preferred IUPAC name:
Aluminium hydroxide

Systematic IUPAC name:
Trihydroxidoaluminium

Trade names:
AB H-Series Alumina Trihydrate
Actilox
ALH-……
ALOLT-……….
Alumina Hydrate
Alumina hydrate
Aluminium hydrate
Aluminium Hydroxide
Aluminium hydroxide
aluminium hydroxide
Aluminium trihydroxide
Aluminiumhydroxid
Aluminum hydroxide
Aluminum hydroxide highly dispersed precipitated
aluminum trihydrate
Apyral
BARIACE
BARIFINE
Bayerit
Geloxal
Hidróxido de aluminio
Hydrate
Hydrated alumina
hydroxid hlinitý
HYMOD® Surface-Treated Alumina Trihydrate
JR-800, MT-500SA etc.
KB-30, HS , HC, Hydrate, Aluminium hydroxide
MARTIFILL®
MARTIFIN®
MARTINAL®
MICRAL® Alumina Trihydrate
MOLDX® Optimized Alumina Trihydrate
ONYX ELITE® Alumina Trihydrate
R-11P
SB Alumina Trihydrate
Sigunit
SSP
STR
T-Lite
VOGA

Other names:
Aluminium oxide, hydrate
Aluminum hydroxide (Al(OH)3)
Aluminum oxide (Al2O3), hydrate
Aluminic acid
Aluminic hydroxide
Alumanetriol
Aluminium(III) hydroxide
Aluminium hydroxide
Aluminium trihydroxide
Hydrated alumina
Orthoaluminic acid

Other identifiers:
106152-09-4
1071843-34-9
12040-59-4
12252-70-9
128083-27-2
1302-29-0
1333-84-2
13783-16-9
151393-94-1
156259-59-5
159704-77-5
16657-47-9
1847408-13-2
21645-51-2
227961-51-5
51330-22-4
546141-62-2
546141-68-8
8012-63-3
8064-00-4
HYDRATED SILICA
HYDRAZINE HYDRATE 64%; Hydrazine, monohydrate; Hidrazina (Spanish); Hydrazine hydroxide; Hydrazinium hydroxide; Idrazina idrata cas no: 302-01-2
HYDRAZINE HYDRATE 100%
Hydrazine hydrate 100% Skip to navigationJump in search Hydrazine hydrate 100% Hydrazine-3D-vdW.pngWater molecule 3D.svg Hydrazine hydrate 100% model Units of SI and STP unless otherwise stated. edit Consult the model documentation The hydrazine hydrate 100% is the chemical compound of formula H 2 N-NH 2H 2 O. It contains 61% hydrazine hydrate 100% by mass and 39% water . Used by the Germans from the 1940s in the B-Stoffs and C-Stoffs for the propulsion of certain airplanes ( Messerschmitt 163B ), hydrazine hydrate 100% is used until today as a reducing propellant in the liquid propellants of certain space launchers . It has in particular been referenced by Arianespace for its Ariane 2 to Ariane 4 launchers in a mixture of 75% UDMH - 25% hydrazine hydrate 100% , called UH 25 . Its melting point is in fact significantly lower than that of pure hydrazine hydrate 100%: −51.7 ° C, against 1 ° C for hydrazine hydrate 100% , and its slightly higher density: 1032 kg · m -3 against 1004.5 kg · m -3 , without degradation of the energy performance of this fuel , which makes it a propellant effective for pitchers . Hydrazine hydrate 100% (Hydrazine, 64%) Hydrazine hydrate 100% is an inorganic compound with the chemical formula N2H 4. It is a simple pnictogen hydride, and is a colorless and flammable liquid with an ammonia-like odor. Hydrazine hydrate 100% is highly toxic unless handled in solution as e.g., hydrazine hydrate 100% (NH2NH2 · xH2O). As of 2015, the world hydrazine hydrate 100% market amounted to $350 million.[8] Hydrazine hydrate 100% is mainly used as a foaming agent in preparing polymer foams, but applications also include its uses as a precursor to polymerization catalysts, pharmaceuticals, and agrochemicals, as well as a long-term storable propellant for in-space spacecraft propulsion. About two million tons of hydrazine hydrate 100% were used in foam blowing agents in 2015. Additionally, hydrazine hydrate 100% is used in various rocket fuels and to prepare the gas precursors used in air bags. Hydrazine hydrate 100% is used within both nuclear and conventional electrical power plant steam cycles as an oxygen scavenger to control concentrations of dissolved oxygen in an effort to reduce corrosion.[9] Hydrazine hydrate 100% refer to a class of organic substances derived by replacing one or more hydrogen atoms in hydrazine hydrate 100% by an organic group.[10] Uses Gas producers and propellants The majority use of hydrazine hydrate 100% is as a precursor to blowing agents. Specific compounds include azodicarbonamide and azobisisobutyronitrile, which produce 100–200 mL of gas per gram of precursor. In a related application, sodium azide, the gas-forming agent in air bags, is produced from hydrazine hydrate 100% by reaction with sodium nitrite.[10] Hydrazine hydrate 100% is also used as a long-term storable propellant on board space vehicles, such as the NASA Dawn probe to Ceres and Vesta, and to both reduce the concentration of dissolved oxygen in and control pH of water used in large industrial boilers. The F-16 fighter jet, NASA Space Shuttle, and U-2 spy plane use hydrazine hydrate 100% to fuel their emergency power units.[11] Precursor to pesticides and pharmaceuticals Fluconazole, synthesized using hydrazine hydrate 100%, is an antifungal medication. Hydrazine hydrate 100% is a precursor to several pharmaceuticals and pesticides. Often these applications involve conversion of hydrazine hydrate 100% to heterocyclic rings such as pyrazoles and pyridazines. Examples of commercialized bioactive hydrazine hydrate 100% derivatives include cefazolin, rizatriptan, anastrozole, fluconazole, metazachlor, metamitron, metribuzin, paclobutrazol, diclobutrazole, propiconazole, hydrazine hydrate 100% sulfate,[12] diimide, triadimefon,[10] and dibenzoylhydrazine hydrate 100%. Hydrazine hydrate 100% compounds can be effective as active ingredients in admixture with or in combination with other agricultural chemicals such as insecticides, miticides, nematicides, fungicides, antiviral agents, attractants, herbicides or plant growth regulators.[13] Small-scale, niche, and research The Italian catalyst manufacturer Acta (chemical company) has proposed using hydrazine hydrate 100% as an alternative to hydrogen in fuel cells. The chief benefit of using hydrazine hydrate 100% is that it can produce over 200 mW/cm2 more than a similar hydrogen cell without the need to use expensive platinum catalysts.[14] As the fuel is liquid at room temperature, it can be handled and stored more easily than hydrogen. By storing the hydrazine hydrate 100% in a tank full of a double-bonded carbon-oxygen carbonyl, the fuel reacts and forms a safe solid called hydrazone. By then flushing the tank with warm water, the liquid hydrazine hydrate 100% is released. Hydrazine hydrate 100% has a higher electromotive force of 1.56 V compared to 1.23 V for hydrogen. Hydrazine hydrate 100% breaks down in the cell to form nitrogen and hydrogen which bonds with oxygen, releasing water.[14] Hydrazine hydrate 100% was used in fuel cells manufactured by Allis-Chalmers Corp., including some that provided electric power in space satellites in the 1960s. A mixture of 63% hydrazine hydrate 100%, 32% hydrazine hydrate 100% nitrate and 5% water is a standard propellant for experimental bulk-loaded liquid propellant artillery. The propellant mixture above is one of the most predictable and stable, with a flat pressure profile during firing. Misfires are usually caused by inadequate ignition. The movement of the shell after a misignition causes a large bubble with a larger ignition surface area, and the greater rate of gas production causes very high pressure, sometimes including catastrophic tube failures (i.e. explosions).[15] From January–June 1991, the U.S. Army Research Laboratory conducted a review of early bulk-loaded liquid propellant gun programs for possible relevance to the electrothermal chemical propulsion program.[15] The United States Air Force (USAF) regularly uses H-70, a 70% hydrazine hydrate 100% water mixture, in operations employing the General Dynamics F-16 “Fighting Falcon” fighter aircraft and the Lockheed U-2 “Dragon Lady” reconnaissance aircraft. The single jet engine F-16 utilizes hydrazine hydrate 100% to power its Emergency Power Unit (EPU), which provides emergency electrical and hydraulic power in the event of an engine flame out. The EPU activates automatically, or manually by pilot control, in the event of loss of hydraulic pressure or electrical power in order to provide emergency flight controls. The single jet engine U-2 utilizes hydrazine hydrate 100% to power its Emergency Starting System (ESS), which provides a highly reliable method to restart the engine in flight in the event of a stall.[16] Rocket fuel Anhydrous (pure, not in solution) hydrazine hydrate 100% being loaded into the MESSENGER space probe. The technician is wearing a safety suit. Hydrazine hydrate 100% was first used as a component in rocket fuels during World War II. A 30% mix by weight with 57% methanol (named M-Stoff in the German Luftwaffe) and 13% water was called C-Stoff by the Germans.[17] The mixture was used to power the Messerschmitt Me 163B rocket-powered fighter plane. Hydrazine was also used as a propellant with the German high test peroxide T-Stoff oxidizer. Unmixed hydrazine was referred to as B-Stoff by the Germans, a designation also used later for the ethanol/water fuel for the V-2 missile. Hydrazine is used as a low-power monopropellant for the maneuvering thrusters of spacecraft, and was used to power the Space Shuttle's auxiliary power units (APUs). In addition, monopropellant hydrazine hydrate 100% -fueled rocket engines are often used in terminal descent of spacecraft. Such engines were used on the Viking program landers in the 1970s as well as the Phoenix lander and Curiosity rover which landed on Mars in May 2008 and August 2012, respectively. In all hydrazine hydrate 100% monopropellant engines, the hydrazine hydrate 100% is passed over a catalyst such as iridium metal supported by high-surface-area alumina (aluminium oxide), which causes it to decompose into ammonia, nitrogen gas, and hydrogen gas according to the following reactions:[18] 1) {\displaystyle {\ce {N2H4 -> N2 + 2H2}}}{\displaystyle {\ce {N2H4 -> N2 + 2H2}}} 2) {\displaystyle {\ce {3N2H4 -> 4 NH3 + N2}}}{\displaystyle {\ce {3N2H4 -> 4 NH3 + N2}}} 3) {\displaystyle {\ce {4NH3 + N2H4 -> 3 N2 + 8 H2}}}{\displaystyle {\ce {4NH3 + N2H4 -> 3 N2 + 8 H2}}} The first two reactions are extremely exothermic (the catalyst chamber can reach 800 °C in a matter of milliseconds,[19]) and they produce large volumes of hot gas from a small volume of liquid,[20] making hydrazine hydrate 100% a fairly efficient thruster propellant with a vacuum specific impulse of about 220 seconds.[21] Reaction 2 is the most exothermic, but produces a smaller number of molecules than that of reaction 1. Reaction 3 is endothermic and reverts the effect of reaction 2 back to the same effect as reaction 1 alone (lower temperature, greater number of molecules). The catalyst structure affects the proportion of the NH3 that is dissociated in reaction 3; a higher temperature is desirable for rocket thrusters, while more molecules are desirable when the reactions are intended to produce greater quantities of gas.[citation needed] Other variants of hydrazine hydrate 100% that are used as rocket fuel are monomethylhydrazine hydrate 100%, (CH3)NH(NH2) (also known as MMH), and unsymmetrical dimethylhydrazine, (CH3)2N(NH2) (also known as UDMH). These derivatives are used in two-component rocket fuels, often together with dinitrogen tetroxide, N2O4. These reactions are extremely exothermic, and the burning is also hypergolic (it starts burning without any external ignition).[22] There are ongoing efforts in the aerospace industry to replace hydrazine hydrate 100% and other highly toxic substances. Promising alternatives include hydroxylammonium nitrate, 2-dimethylaminoethylazide (DMAZ)[23] and energetic ionic liquids.[citation needed] Potential routes of hydrazine hydrate 100% exposure include dermal, ocular, inhalation and ingestion.[24] Hydrazine hydrate 100% exposure can cause skin irritation/contact dermatitis and burning, irritation to the eyes/nose/throat, nausea/vomiting, shortness of breath, pulmonary edema, headache, dizziness, central nervous system depression, lethargy, temporary blindness, seizures and coma. Exposure can also cause organ damage to the liver, kidneys and central nervous system.[24][25] Hydrazine hydrate 100% is documented as a strong skin sensitizer with potential for cross-sensitization to hydrazine hydrate 100% derivatives following initial exposure.[26] In addition to occupational uses reviewed above, exposure to hydrazine hydrate 100% is also possible in small amounts from tobacco smoke.[25] The official U.S. guidance on hydrazine hydrate 100% as a carcinogen is mixed but generally there is recognition of potential cancer-causing effects. The National Institute for Occupational Safety and Health (NIOSH) lists it as a “potential occupational carcinogen”. The National Toxicology Program (NTP) finds it is "reasonably anticipated to be a human carcinogen". The American Conference of Governmental Industrial Hygienists (ACGIH) grades hydrazine hydrate 100% as "A3—confirmed animal carcinogen with unknown relevance to humans". The U.S. Environmental Protection Agency (EPA) grades it as "B2—a probable human carcinogen based on animal study evidence".[27] The International Agency for Research on Cancer (IARC) rates hydrazine hydrate 100% as "2A—probably carcinogenic to humans" with a positive association observed between hydrazine hydrate 100% exposure and lung cancer.[28] Based on cohort and cross-sectional studies of occupational hydrazine hydrate 100% exposure, a committee from the National Academies of Sciences, Engineering and Medicine concluded that there is suggestive evidence of an association between hydrazine hydrate 100% exposure and lung cancer, with insufficient evidence of association with cancer at other sites.[29] The European Commission’s Scientific Committee on Occupational Exposure Limits (SCOEL) places hydrazine hydrate 100% in carcinogen “group B—a genotoxic carcinogen”. The genotoxic mechanism the committee cited references hydrazine hydrate 100% reaction with endogenous formaldehyde and formation of a DNA-methylating agent.[30] In the event of a hydrazine hydrate 100% exposure-related emergency, NIOSH recommends removing contaminated clothing immediately, washing skin with soap and water, and for eye exposure removing contact lenses and flushing eyes with water for at least 15 minutes. NIOSH also recommends anyone with potential hydrazine hydrate 100% exposure to seek medical attention as soon as possible.[24] There are no specific post-exposure laboratory or medical imaging recommendations, and the medical work-up may depend on the type and severity of symptoms. The World Health Organization (WHO) recommends potential exposures be treated symptomatically with special attention given to potential lung and liver damage. Past cases of hydrazine hydrate 100% exposure have documented success with Pyridoxine (Vitamin B6) treatment.[26] Occupational exposure limits NIOSH Recommended Exposure Limit (REL): 0.03 ppm (0.04 mg/m3) 2-hour ceiling[27] OSHA Permissible Exposure Limit (PEL): 1 ppm (1.3 mg/m3) 8-hour Time Weighted Average[27] ACGIH Threshold Limit Value (TLV): 0.01 ppm (0.013 mg/m3) 8-hour Time Weighted Average[27] The odor threshold for hydrazine hydrate 100% is 3.7 ppm, thus if a worker is able to smell an ammonia-like odor then they are likely over the exposure limit. However, this odor threshold varies greatly and should not be used to determine potentially hazardous exposures.[31] For aerospace personnel, the USAF uses an emergency exposure guideline, developed by the National Academy of Science Committee on Toxicology, which is utilized for non-routine exposures of the general public and is called the Short-Term Public Emergency Exposure Guideline (SPEGL). The SPEGL, which does not apply to occupational exposures, is defined as the acceptable peak concentration for unpredicted, single, short-term emergency exposures of the general public and represents rare exposures in a worker's lifetime. For hydrazine hydrate 100% the 1-hour SPEGL is 2 ppm, with a 24-hour SPEGL of 0.08 ppm.[32] Handling and medical surveillance A complete surveillance program for hydrazine hydrate 100% should include systematic analysis of biologic monitoring, medical screening and morbidity/mortality information. The CDC recommends surveillance summaries and education be provided for supervisors and workers. Pre-placement and periodic medical screening should be conducted with specific focus on potential effects of hydrazine hydrate 100% upon functioning of the eyes, skin, liver, kidneys, hematopoietic, nervous and respiratory systems.[24] Common controls used for hydrazine hydrate 100% include process enclosure, local exhaust ventilation and personal protective equipment (PPE).[24] Guidelines for hydrazine hydrate 100% PPE include non-permeable gloves and clothing, indirect-vent splash resistant goggles, face shield and in some cases a respirator.[31] The use of respirators for the handling of hydrazine hydrate 100% should be the last resort as a method of controlling worker exposure. In cases where respirators are needed, proper respirator selection and a complete respiratory protection program consistent with OSHA guidelines should be implemented.[24] For USAF personnel, Air Force Occupational Safety and Health (AFOSH) Standard 48-8, Attachment 8 reviews the considerations for occupational exposure to hydrazine hydrate 100% in missile, aircraft and spacecraft systems. Specific guidance for exposure response includes mandatory emergency shower and eyewash stations and a process for decontaminating protective clothing. The guidance also assigns responsibilities and requirements for proper PPE, employee training, medical surveillance and emergency response.[32] USAF bases requiring the use of hydrazine hydrate 100% generally have specific base regulations governing local requirements for safe hydrazine hydrate 100% use and emergency response. Molecular structure Each H2N−N subunit is pyramidal. The N−N single bond distance is 1.45 Å (145 pm), and the molecule adopts a gauche conformation.[33] The rotational barrier is twice that of ethane. These structural properties resemble those of gaseous hydrogen peroxide, which adopts a "skewed" anticlinal conformation, and also experiences a strong rotational barrier. Synthesis and production Diverse routes have been developed.[10] The key step is the creation of the nitrogen–nitrogen single bond. The many routes can be divided into those that use chlorine oxidants (and generate salt) and those that do not. Oxidation of ammonia via oxaziridines from peroxide Hydrazine hydrate 100% can be synthesized from ammonia and hydrogen peroxide in the Peroxide process (sometimes called Pechiney-Ugine-Kuhlmann process, the Atofina–PCUK cycle, or ketazine process).[10] The net reaction follows:[34] {\displaystyle {\ce {2NH3 + H2O2 -> H2NNH2 + 2H2O}}}{\displaystyle {\ce {2NH3 + H2O2 -> H2NNH2 + 2H2O}}} In this route, the ketone and ammonia first condense to give the imine, which is oxidised by hydrogen peroxide to the oxaziridine, a three-membered ring containing carbon, oxygen, and nitrogen. Next, the oxaziridine gives the hydrazone by treatment with ammonia, which process creates the nitrogen-nitrogen single bond. This hydrazone condenses with one more equivalent of ketone. Pechiney-Ugine-Kuhlmann process.png The resulting azine is hydrolyzed to give hydrazine hydrate 100% and regenerate the ketone, methyl ethyl ketone: {\displaystyle {\ce {Me(Et)CNNC(Et)Me + 2 H2O -> 2 Me(Et)CO + N2H4}}}{\displaystyle {\ce {Me(Et)CNNC(Et)Me + 2 H2O -> 2 Me(Et)CO + N2H4}}} Unlike most other processes, this approach does not produce a salt as a by-product.[35] Chlorine-based oxidations In the Olin Raschig process, chlorine-based oxidants oxidize ammonia without the presence of a ketone. In the peroxide process, hydrogen peroxide oxidizes ammonia in the presence of a ketone. Hydrazine hydrate 100% is produced in the Olin-Raschig process from sodium hypochlorite (the active ingredient in many bleaches) and ammonia, a process announced in 1907. This method relies on the reaction of monochloramine with ammonia to create the nitrogen–nitrogen single bond as well as a hydrogen chloride byproduct:[12] {\displaystyle {\ce {NH2Cl + NH3 -> H2NNH2 + HCl}}}{\displaystyle {\ce {NH2Cl + NH3 -> H2NNH2 + HCl}}} Related to the Raschig process, urea can be oxidized instead of ammonia. Again sodium hypochlorite serves as the oxidant. The net reaction is shown:[36] {\displaystyle {\ce {(H2N)2CO + NaOCl + 2 NaOH -> N2H4 + H2O + NaCl + Na2CO3}}}{\displaystyle {\ce {(H2N)2CO + NaOCl + 2 NaOH -> N2H4 + H2O + NaCl + Na2CO3}}} The process generates significant byproducts and is mainly practised in Asia.[10] The Bayer Ketazine Process is the predecessor to the peroxide process. It employs sodium hypochlorite as oxidant instead of hydrogen peroxide. Like all hypochlorite-based routes, this method produces an equivalent of salt for each equivalent of hydrazine hydrate 100%.[10] Reactions Acid-base behavior Hydrazine hydrate 100% forms a monohydrate that is more dense (1.032 g/cm3) than the anhydrous material. Hydrazine hydrate 100% has basic (alkali) chemical properties comparable to those of ammonia:[37] {\displaystyle {\ce {N2H4 + H2O -> [N2H5]^+ + OH-}}}{\displaystyle {\ce {N2H4 + H2O -> [N2H5]^+ + OH-}}}{\displaystyle ,\ K_{b}=1.3\times 10^{-6},\ pK_{a}=8.1}{\displaystyle ,\ K_{b}=1.3\times 10^{-6},\ pK_{a}=8.1} (for ammonia {\textstyle K_{b}=1.78\times 10^{-5}}{\textstyle K_{b}=1.78\times 10^{-5}}) It is difficult to diprotonate:[38] {\displaystyle {\ce {[N2H5]+ + H2O -> [N2H6]^2+ + OH-}}}{\displaystyle {\ce {[N2H5]+ + H2O -> [N2H6]^2+ + OH-}}} {\displaystyle ,\ K_{b}=8.4\times 10^{-16},\ pK_{a}=-1.1}{\displaystyle ,\ K_{b}=8.4\times 10^{-16},\ pK_{a}=-1.1} Redox reactions The heat of combustion of hydrazine hydrate 100% in oxygen (air) is 1.941 × 107 J/kg (8345 BTU/lb).[39] Hydrazine hydrate 100% is a convenient reductant because the by-products are typically nitrogen gas and water. Thus, it is used as an antioxidant, an oxygen scavenger, and a corrosion inhibitor in water boilers and heating systems. It is also used to reduce metal salts and oxides to the pure metals in electroless nickel plating and plutonium extraction from nuclear reactor waste. Some color photographic processes also use a weak solution of hydrazine hydrate 100% as a stabilizing wash, as it scavenges dye coupler and unreacted silver halides. Hydrazine hydrate 100% is the most common and effective reducing agent used to convert graphene oxide (GO) to reduced graphene oxide (rGO) via hydrothermal treatment.[40] Hydrazinium salts Hydrazine hydrate 100% can be monoprotonated to form various solid salts of the hydrazinium cation (N2H5+) by treatment with mineral acids. A common salt is hydrazinium sulfate, [N2H5]HSO4, also called hydrazine hydrate 100% sulfate.[41] Hydrazine hydrate 100% sulfate was investigated as a treatment of cancer-induced cachexia, but proved ineffective.[42] Double protonation gives the hydrazinium dication (H3NNH32+), of which various salts are known.[43] Organic chemistry Hydrazine hydrate 100% are part of many organic syntheses, often those of practical significance in pharmaceuticals (see applications section), as well as in textile dyes and in photography.[10] Hydrazine hydrate 100% is used in the Wolff-Kishner reduction, a reaction that transforms the carbonyl group of a ketone into a methylene bridge (or an aldehyde into a methyl group) via a hydrazone intermediate. The production of the highly stable dinitrogen from the hydrazine hydrate 100% derivative helps to drive the reaction. Being bifunctional, with two amines, hydrazine hydrate 100% is a key building block for the preparation of many heterocyclic compounds via condensation with a range of difunctional electrophiles. With 2,4-pentanedione, it condenses to give the 3,5-dimethylpyrazole.[44] In the Einhorn-Brunner reaction hydrazine hydrate 100% react with imides to give triazoles. Being a good nucleophile, N2H4 can attack sulfonyl halides and acyl halides.[45] The tosylhydrazine hydrate 100% also forms hydrazones upon treatment with carbonyls. Hydrazine hydrate 100% is used to cleave N-alkylated phthalimide derivatives. This scission reaction allows phthalimide anion to be used as amine precursor in the Gabriel synthesis.[46] Hydrazone formation Illustrative of the condensation of hydrazine hydrate 100% with a simple carbonyl is its reaction with propanone to give the diisopropylidene hydrazine hydrate 100% (acetone azine). The latter reacts further with hydrazine hydrate 100% to yield the hydrazone:[47] {\displaystyle {\ce {2 (CH3)2CO + N2H4 -> 2 H2O + [(CH3)2C=N]2}}}{\displaystyle {\ce {2 (CH3)2CO + N2H4 -> 2 H2O + [(CH3)2C=N]2}}} {\displaystyle {\ce {[(CH3)2C=N]2 + N2H4 -> 2 (CH3)2C=NNH2}}}{\displaystyle {\ce {[(CH3)2C=N]2 + N2H4 -> 2 (CH3)2C=NNH2}}} The propanone azine is an intermediate in the Atofina-PCUK process. Direct alkylation of hydrazine hydrate 100% with alkyl halides in the presence of base yields alkyl-substituted hydrazine hydrate 100%, but the reaction is typically inefficient due to poor control on level of substitution (same as in ordinary amines). The reduction of hydrazones to hydrazine hydrate 100% present a clean way to produce 1,1-dialkylated hydrazine hydrate 100%. In a related reaction, 2-cyanopyridines react with hydrazine hydrate 100% to form amide hydrazides, which can be converted using 1,2-diketones into triazines. Biochemistry Hydrazine hydrate 100% is the intermediate in the anaerobic oxidation of ammonia (anammox) process.[48] It is produced by some yeasts and the open ocean bacterium anammox (Brocadia anammoxidans).[49] The false morel produces the poison gyromitrin which is an organic derivative of hydrazine hydrate 100% that is converted to monomethylhydrazine hydrate 100% by metabolic processes. Even the most popular edible "button" mushroom Agaricus bisporus produces organic hydrazine hydrate 100% derivatives, including agaritine, a hydrazine hydrate 100% derivative of an amino acid, and gyromitrin.[50][51] History The name "hydrazine hydrate 100% " was coined by Emil Fischer in 1875; he was trying to produce organic compounds that consisted of mono-substituted hydrazine hydrate 100%.[52] By 1887, Theodor Curtius had produced hydrazine hydrate 100% sulfate by treating organic diazides with dilute sulfuric acid; however, he was unable to obtain pure hydrazine hydrate 100%, despite repeated efforts.[53][54][55] Pure anhydrous hydrazine hydrate 100% was first prepared by the Dutch chemist Lobry de Bruyn in 1895.[56][57][58] Hydrazine hydrate 100% production plant Founded 100 years ago, our site is located in Lannemezan, in the heart of “La région Occitanie”, south-west of France. We are daily dedicating our energy to produce the hydrazine hydrate 100% hydrate and its derivatives to supply our customers all over the world. Lannemezan is classified SEVESO class 2 high level. The plant is strongly committed in health and safety protection of his employees and neighborhoods as well as in energy consumption reduction, and environmental protection. Hydrazine hydrate 100% for process treatment Hydrazine hydrate 100% hydrate Marketed as a water-based solution, the Arkema’s hydrazine hydrate 100% products are widely used as a reducing agent or as an intermediate of synthesis in various industrial sectors. COMMERCIAL GRADE Our Hydrazine hydrate 100% is available in different concentration, which are suitable for specifics applications: • Hydrazine hydrate 100% • Hydrazine hydrate 80% • Hydrazine hydrate 55% • Hydrazine hydrate 35% • Hydrazine hydrate 24% Product Description Hydrazine hydrate 100% is a colorless liquid with an odor similar to that of ammonia . Hydrazine hydrate 100% is widely used in various applications such as the deoxygenation of boiler water, preparation of chemical blowing agents, preparation of intermediates for pharmaceutical and agricultural chemicals, reducing agent for metals and halogens and chain extension of aqueous urethane formulations. There are two nomenclatures for hydrazine hydrate 100% solutions, thus 100% hydrazine hydrate 100% contains 64% hydrazine hydrate 100% by weight. Hydrazine hydrate 100% is miscible with water and lower alcohols. Typical properties and specifications for standard solutions offered by Arch are given in Tables 1 and 2. Arch also offers catalyzed hdyrazine solutions for boiler water treatment. A summary of the compatibility of various materials of construction for use with hydrazine hydrate 100% is shown in Table 3 Palm International's Hydrazine Hydrate 100% Regular Grade 100% is especially produced for use as an oxygen scavenger, in blowing agents, polymers, pigments, dyes and other industrial applications. It is subject to stringent quality control standards and testing. Hydrazine Hydrate 100% Regular Grade 100% is available in 2,875 Lb returnable SS totes, 450 Lb / 250 Lb poly drums as well as bulk. Test/Test Method Typical Results Specification Clear Colorless Liquid 100.4% 100.0 - 100.8% 64.3% 35.7% Appearance Hydrazine Hydrate 100% Hydrazine Hydrate 100% Hydrazine hydrate 100% (N2H4) hydrazine hydrate 100% solution is supplied in various concentrations, including 100%, 85%, and 55%. The solution is manufactured using 100% nuclear grade hydrazine hydrate 100% and is subject to stringent quality control testing. The hydrazine hydrate 100% solution is available in 2875 lb. SS totes and 450 lb. poly drums, as well as in bulk. Azines (2,3-diazabuta-1,3-dienes) are a widely used class of compounds with conjugated C=N double bonds. Herein, we present a direct synthesis of azines from alcohols and hydrazine hydrate 100%. The reaction, catalyzed by a ruthenium pincer complex, evolves dihydrogen and can be run in a base-free version. The dehydrogenative coupling of benzylic and aliphatic alcohols led to good conversions and yields. Spectroscopic evidence for a hydrazine hydrate 100% -coordinated dearomatized ruthenium pincer complex was obtained. Isolation of a supramolecular crystalline compound provided evidence for the important role of hydrogen bonding networks under the reaction conditions. Keywords: azines; homogeneous catalysis; hydrogen bonds; pincer complexes; ruthenium; supramolecular compounds. In the present study, five new derivatives (GG4 to GG8) of benzothiazoles were synthesized and evaluated against Staphylococcus aureus (MTCC 737), Pseudomonas aeruginosa (MTCC 424), Escherichia coli (MTCC 1687), and yeast-like fungi Candida tropicalis. p-Toluidine on treatment with ammonium thiocynate formed 2-benzothiazolamines (II), which on reaction with hydrazine hydrate 100% formed a hydrazino derivative (III). Compounds GG4 to GG8 were synthesized by reacting the hydrazine hydrate 100% derivative with different acetophenones. All the synthesized compounds were identified by IR and (1)H-NMR, and antimicrobial activity was performed on the synthesized compounds. Presence of NO(2), Br, OCH(3), and Cl groups to the substituted benzothiazole enhanced the antibacterial and antifungal activities. Green and cost-effective eradication of pollutants from water is an important and long-standing goal in environmental chemistry. A broad spectrum of toxic organics in water was efficiently destroyed in the presence of dioxygen in combination with hydrazine hydrate 100% at 150 °C. Under this operating condition, two typical classes of toxic organic chemicals, phenols and nitrobenzene derivatives were totally destroyed. The mineralization rate of these organics was 35-86%. Furthermore, when this degradation system was applied to degradation of actual waste water of wood pulp bleaching with chlorine (COD: 1830 mg/L), 77% COD decrease and 52% TOC mineralization of the wastewater were observed. In each case, the major degradation products are small molecular compounds, such as methanol, formic acid and acetic acid except CO/CO(2). In the case of chlorophenols degradation, no dioxins and any other toxic compounds are detected by (1)H NMR. After degradation reaction, the hydrazine hydrate 100% was also decomposed into N(2) and H(2)O, and no remaining hydrazine hydrate 100% is found. Uses Hydrazine hydrate 100% is used as a reducing agent in synthetic and analytical reactions and as a solvent for many inorganic compounds. It also is used with methanol as a propellant for rocket engines. Another application is catalytic decomposition of hydrogen peroxide. Preparation Hydrazine hydrate 100% is prepared by treating hydrazine hydrate 100% sulfate, N2H4•H2SO4 with sodium hydroxide. The product is collected by distillation under nitrogen. It also is obtained as a by-product in the Bayer Ketazine process for producing hydrazine hydrate 100% in which hydrazine hydrate 100% solution is hydrolysed under pressure in a ketazine column. General Description A colorless fuming liquid with a faint ammonia-like odor. Corresponds to a 64% aqueous solution of hydrazine hydrate 100% in water. Combustible but may require some effort to ignite. Contact with oxidizing materials may cause spontaneous ignition. Toxic by inhalation and by skin absorption. Corrosive to tissue. Produces toxics oxides of nitrogen during combustion. Air & Water Reactions Fumes in air. Water soluble. Reactivity Profile Hydrazine hydrate 100% is a base and a very powerful reducing agent. Very corrosive. Violent reaction on contact with alkali metals (sodium, potassium), 2,4-dinitrochlorobenzene, tin dichloride, mercury oxide. Vigorous neutralization reaction with acids. Emits toxic fumes of nitrogen oxides when heated to decomposition [Lewis, 3rd ed., 1993, p. 680]. Reacts with tin(II) chloride to give tin(II) dihydrazine chloride, which decomposes explosively when heated [Mellor 7:430(1946-1947)]. Reacts exothermically and violently with 2,4-dinitrochlorobenzene [Wischmeyer (1967)].
HYDRAZINE HYDRATE 55%
CAS: 7803-57-8
Molecular Formula: H6N2O

Hydrazine hydrate 55% CAS.7803-57-8 is colorless smoke liquid, slightly special smell.
Hydrazine hydrate 55% can be miscible with water and ethanol, insoluble in chloroform and ether.
The use of Hydrazine hydrate 55% as raw material to produce ADC foaming agent, the gas significantly significantly higher than other similar products, and products non-toxic, tasteless, no discoloration, no deterioration.

Our high quality Hydrazine Hydrate 55% is very popular with our customers.
Hydrazine hydrate 55% can be used as a pharmaceutical intermediate for the production of high-purity metals, pesticides, antioxidants, synthetic fiber raw materials, dyes, ADC foaming agents, high-pressure boiler deoxidizers, reducing agents, etc.

Uses of Hydrazine hydrate 55%:
Hydrazine hydrate 55% is used as a reducing agent in synthetic and analytical reactions and as a solvent for many inorganic compounds.
Hydrazine hydrate 55% also is used with methanol as a propellant for rocket engines.
Another application of Hydrazine hydrate 55% is catalytic decomposition of hydrogen peroxide.

Applications of Hydrazine hydrate 55%:
-Polymer auxiliaries
-Manufacturing of herbicides
-Agriculture
-Pesticides
-Energy
-Manufacturing of pharmaceutical agents
-Pharmaceutical industry / Biotechnology
-Plastic- and Rubberpolymers
-Chemical synthesis
-Chemical Industry
-Reduction agents
-Water Treatment
-Industrial water
-Purification of chemical solutions

Hydrazine hydrate 55% is an inorganic compound with the chemical formula N2H4.
Hydrazine hydrate 55% is a simple pnictogen hydride, and is a colourless flammable liquid with an ammonia-like odour.

Hydrazine hydrate 55% is mainly used as a foaming agent in preparing polymer foams, but applications also include its uses as a precursor to polymerization catalysts, pharmaceuticals, and agrochemicals, as well as a long-term storable propellant for in-space spacecraft propulsion.
Hydrazine hydrate 55% has been used for the deproteination of the enamel samples in a study.

Hydrazine hydrate 55% may be used as a reducing agent in the following:
-Preparation of silver nanoparticles.
-Transformation of monosubstituted nitrobenzene derivatives to the corresponding anilines.
-Along with graphite for the conversion of nitro compounds (aromatic and aliphatic) to the amino compounds.

About two million tons of hydrazine hydrate were used in foam blowing agents in 2015.
Additionally, Hydrazine hydrate 55% is used in various rocket fuels and to prepare the gas precursors used in air bags.
Hydrazine hydrate 55% is used within both nuclear and conventional electrical power plant steam cycles as an oxygen scavenger to control concentrations of dissolved oxygen in an effort to reduce corrosion.
Hydrazines refer to a class of organic substances derived by replacing one or more hydrogen atoms in hydrazine by an organic group.

Uses of Hydrazine hydrate 55%:
The majority use of Hydrazine hydrate 55% is as a precursor to blowing agents.
Specific compounds include azodicarbonamide and azobisisobutyronitrile, which produce 100–200 mL of gas per gram of precursor.
In a related application of Hydrazine hydrate 55%, sodium azide, the gas-forming agent in air bags, is produced from hydrazine by reaction with sodium nitrite.

Color: Undesignated,Undesignated
Boiling Point: 109.4C,109.4C
Flash Point: >100C,>100C
Specific Gravity: 1.023,1.023
Melting Point: -65.0C, 65.0C
Packaging: Glass bottle,Glass bottle
Refractive Index: 1.3870 to 1.3910,1.3870 to 1.3910
Assay Percent Range: 55%

Chemical Properties of Hydrazine hydrate 55%: clear colorless solution

Uses of Hydrazine hydrate 55%:
Hydrazine hydrate 55% may be used to prepare:
3-(2-Benzyloxy-6-hydroxyphenyl)-5-styrylpyrazoles by reacting with 5-benzyloxy-2-styrylchromones.
3,5-Diphenyl-2-pyrazoline derivatives by reacting with 1,3-diphenyl-2-propen-1-one.
3′-Aryl-1,2,3,4,4′,5′-hexahydrospiro[quinoxalin-2,5′-pyrazol]-3-ones by reacting with 3-arylacylidene-3,4-dihydroquinoxalin-2(1H)-ones.
Hydrazine hydrate 55% may also be used in the catalytic reduction of nitroarenes to aromatic amines.

Uses of Hydrazine hydrate 55%:
Hydrazine hydrate 55% solution has been used as a reducing agent for tellurium oxide during the preparation of tellurium nanowires.

General Description of Hydrazine hydrate 55%:
The addition of Hydrazine hydrate 55% to reduced graphene oxide (RGO) counter electrode improves its performance in dye-sensitized solar cells (DSSC).

Purification Methods of Hydrazine hydrate 55%:
Hydrazine hydrate 55% can be obtained as above and diluted as required.
Solutions containing various amounts of H2O are available commercially.

Hydrazine hydrate 55% is used as an alternative to hydrogen in fuel cells.
The chief benefit of using Hydrazine hydrate 55% is that it can produce over 200 mW/cm2 more than a similar hydrogen cell without the need to use expensive platinum catalysts.
As the fuel is liquid at room temperature, it can be handled and stored more easily than hydrogen.
By storing the Hydrazine hydrate 55% in a tank full of a double-bonded carbon-oxygen carbonyl, the fuel reacts and forms a safe solid called hydrazone.

By then flushing the tank with warm water, the liquid Hydrazine hydrate 55% is released.
Hydrazine hydrate 55% has a higher electromotive force of 1.56 V compared to 1.23 V for hydrogen.
Hydrazine hydrate 55% breaks down in the cell to form nitrogen and hydrogen which bonds with oxygen, releasing water.
Hydrazine hydrate 55% was used in fuel cells including some that provided electric power in space satellites in the 1960s.

Medical Industry:
Hydrazine hydrate 55% and includ its derivatives can be used for productions of numerous medicines like rifampin and cephalosporin.

As a Deoxidant:
Hydrazine is a reducing agent, its oxidation reaction generates nitrogen water and gas that are nontoxic corrosive and not nontoxic.
Hydrazine hydrate 55% is used as a quick deoxidant in water, the largest application being a deoxidant for Water Treatment.

Production of Blowing Agents:
Hydrazine hydrate 55% can be used for many kinds of rubbers and plastics chemicals.
Hydrazine hydrate 55% produces ADC blowing agent has more gas emission rate than that of other blowing agents, and the manufactures products are nontoxic, non-color changing, odorless with more stable properties.

Synthesis of Agrochemicals:
Triazole - a derivative of hydrazine - and Hydrazine hydrate 55% can synthesis more than one hundred various of the agrochemicals.

Trade Name: Hydrazine Hydrate/ 7803-57-8/ Hydrazine monohydrate/ Hydrazine hydroxide

Molecular Formula: N2H4·H2O
Molecular Weight: 50.08
Appearance: colorless, fuming and basic solution with a peculiar bad smell.
Product Property: Hydrazine hydrate 55% is a colorless, fuming and basic solution with a peculiar bad smell, soluble in water and alcohol, insoluble in chloroform and ethyl ether, flammable and corroding glass, rubber and leather, its severe toxicity accumulates and harms blood and nerves.
Cas No.: 7803-57-8 HS Code: 28251010
Usage: This product is a reductive agent used as materials of medicine, pesticides, dyestuff, blowing agent and photographic developer.
Package: in plastic drums with 200kg net each.
Implementing Standard: HG/T3259-1990

Specifications of Hydrazine Hydrate 55% , CAS#: 10217-52-4: :
Appearance: colorless fuming liquid
Melting Point: -51.7 °C
Boiling Point: 113.5 °C at 760 mmHg
density:1.03 g/mL at 20 °C
vapor density : >1 (vs air)
vapor pressure :5 mm Hg ( 25 °C)
refractive index : n20/D 1.428(lit.)
Fp : 204 °F
storage temp.: Refrigerator (+4°C)
Solubility: miscible with water
Transport Information: UN 2029/2030

Usage of Hydrazine Hydrate 55%:
Hydrazine hydrate 55% is the material for medicine, pesticides, dyes, foaming agents, imaging agent, antioxidant;
Hydrazine hydrate 55% was spent large for boiler water Deoxidizer;
Hydrazine hydrate 55% also used in the manufacture of high-purity metal, synthetic fiber, the separation of rare.
Hydrazine hydrate 55% is used to manufacture rockets and explosives.
Hydrazine hydrate 55% is also used as a Analysis reagent.
Hydrazine hydrate 55% can be used in Synthesis of foaming agent,such as Azodicarbonamide (AC), p-toluenesulfonic acid hydrazide.

Storage of Hydrazine hydrate 55%:
Flammable materials should be stored in a separate safety storage cabinet or room.
Keep away from heat.
Keep away from sources of ignition.
Keep container tightly closed.
Keep in a cool, well-ventilated place.
Ground all equipment containing material.
Keep container dry. Keep in a cool place.

Appearance: Colorless, fuming, oily liquid
Odor: Ammonia-like
Density: 1.021 g·cm−3
Melting point: 2 °C; 35 °F; 275 K
Boiling point: 114 °C; 237 °F; 387 K
Solubility in water: Miscible
log P: 0.67
Vapor pressure: 1 kPa (at 30.7 °C)
Acidity (pKa): 8.10 (N2H5+)[4]
Basicity (pKb): 5.90
Conjugate acid: Hydrazinium
Refractive index (nD): 1.46044 (at 22 °C)
Viscosity: 0.876 cP
Flash point: 52 °C (126 °F; 325 K)
Autoignition temperature: 24 to 270 °C (75 to 518 °F; 297 to 543 K)
Explosive limits: 1.8–99.99%
XLogP3-AA: -1.5
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 0
Exact Mass: 32.037448136
Monoisotopic Mass: 32.037448136
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 2
Complexity: 0
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

History of Hydrazine Hydrate:
The name "hydrazine" was coined by Emil Fischer in 1875; he was trying to produce organic compounds that consisted of mono-substituted hydrazine.
By 1887, Theodor Curtius had produced hydrazine sulfate by treating organic diazides with dilute sulfuric acid; however, he was unable to obtain pure hydrazine, despite repeated efforts.
Pure anhydrous hydrazine was first prepared by the Dutch chemist Lobry de Bruyn in 1895.

Release to the environment of Hydrazine hydrate 55% can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.
Hydrazine hydrate 55% can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles not covered by End of Life Vehicles (ELV) directive (e.g. boats, trains, metro or planes).

Widespread uses of Hydrazine Hydrazine hydrate 55% by professional workers:
Hydrazine hydrate 55% is used in the following products: pH regulators and water treatment products, laboratory chemicals and fuels.
Hydrazine hydrate 55% is used in the following areas: health services and scientific research and development.
Other release to the environment of Hydrazine hydrate 55% is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Uses of Hydrazine hydrate 55% at industrial sites:
Hydrazine hydrate 55% is used in the following products: laboratory chemicals, water treatment chemicals, fuels, pH regulators and water treatment products and polymers.
Hydrazine hydrate 55% has an industrial use resulting in manufacture of another substance (use of intermediates).
Hydrazine hydrate 55% is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and scientific research and development.
Hydrazine hydrate 55% is used for the manufacture of: chemicals, metals, machinery and vehicles and plastic products.
Release to the environment of Hydrazine hydrate 55% can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and of substances in closed systems with minimal release.

Synonyms
Hydrazinium hydrate
HYDRAZINE HYDRATE 55
HYDRAZINIUM HYDROXIDE
HYDRAZINE MONOHYDRATE
Hydrazine hydrate soln
Hydrazine hydrate, 98+%
Hydrazinium monohydroxide
HydraziniuM hydrate solution
Hydrazinium hydroxide solution
Hydrazine Monohydrate, 98.0%(T)
hydrazinium hydroxide
hydrazine hydrate, 98+%
hydrazinium hydroxide solution
Hydrazine hydrate
7803-57-8
hydrazin hydrate
hydrazine hydrat
hyrazine hydrate
hydrate hydrazine
hydrazine-hydrate
hydrazine.hydrate
hydrazine H2O
Hydrazine, hydrate (6CI,7CI)
hydrazin, hydrate
Hydrazine monohydrate pound>>Hydrazinium hydroxide pound>>Hydrazinehydrate
hydrazine hydrate 55
hydrazine monohydrate, 98.0%(t)
hydrazine hydrate, 64% hydrazine
hydrazine hydrate soln
hydrazine monohydrate
hydrazinium hydrate
hydrazinium hydrate solution
HYDRAZINE HYDRATE 64%
Hydrazinium hydroxide; Hydrazine, monohydrate; Hidrazina (Spanish); Hydrazine hydroxide; Idrazina idrata (Italian); CAS NO:7803-57-8
Hydrazine hydrate
Anhydrous hydrogen chloride; Spirits of salt; Hydrochloric acid, Anhydrous; Basilin; Chlorohydric acid; Hydrochloride; Muriatic acid; Acide chlorhydrique; Acido cloridrico; Chloorwaterstof; Chlorowodor; Chlorwasserstoff CAS NO: 7647-01-0
HYDROACETIC ACID (GLYCOLIC ACID)
Hydroacetic acid (Glycolic Acid) is a constituent of sugar cane juice
Hydroacetic acid (Glycolic Acid) is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroacetic acid (Glycolic Acid) has a role as a metabolite and a keratolytic drug.


CAS Number: 79-14-1
EC Number: 201-180-5
MDL Number: MFCD00004312
Molecular Formula: C2H4O3 / HOCH2COOH



glycolic acid, 2-Hydroxyacetic acid, hydroxyacetic acid, 79-14-1, Hydroxyethanoic acid, Glycollic acid, Acetic acid, hydroxy-, glycolate, Polyglycolide, Caswell No. 470, 2-Hydroxyethanoic acid, HOCH2COOH, alpha-Hydroxyacetic acid, Acetic acid, 2-hydroxy-, EPA Pesticide Chemical Code 000101, HSDB 5227, NSC 166, Glycocide, GlyPure, BRN 1209322, NSC-166, EINECS 201-180-5, UNII-0WT12SX38S, MFCD00004312, GlyPure 70, 0WT12SX38S, CCRIS 9474, DTXSID0025363, CHEBI:17497, Hydroxyacetic acid-13C2, .alpha.-Hydroxyacetic acid, GLYCOLLATE, DTXCID105363, NSC166, EC 201-180-5, 4-03-00-00571 (Beilstein Handbook Reference), GOA, GLYCOLIC ACID (MART.), GLYCOLIC ACID [MART.], C2H3O3-, glycolicacid, C2H4O3, Glycolate Standard: C2H3O3- @ 1000 microg/mL in H2O,
Hydroxyethanoate, a-Hydroxyacetate, OceanBlu Barrier, OceanBlu Pre-Post, hydroxy-acetic acid, 2-Hydroxyaceticacid, alpha-Hydroxyacetate, a-Hydroxyacetic acid, 2-hydroxy acetic acid, 2-hydroxy-acetic acid, 2-hydroxyl ethanoic acid, HO-CH2-COOH, Hydroxyacetic acid solution, bmse000245, WLN: QV1Q,
GLYCOLIC ACID [MI], Glycolic acid (7CI,8CI), GLYCOLIC ACID [INCI], GLYCOLIC ACID [VANDF], Glycolic acid, p.a., 98%, pari 30% Glycolic Acid Peel, pari 70% Glycolic Acid Peel, Acetic acid, hydroxy- (9CI), CHEMBL252557, GLYCOLIC ACID [WHO-DD], Glycolic Acid, Crystal, Reagent, HYDROXYACETIC ACID [HSDB],
BCP28762, Glycolic acid, >=97.0% (T), STR00936, Tox21_301298, s6272, AKOS000118921, Glycolic acid, ReagentPlus(R), 99%, CS-W016683, DB03085, HY-W015967, SB83760, CAS-79-14-1, USEPA/OPP Pesticide Code: 000101, NCGC00160612-01, NCGC00160612-02, NCGC00257533-01, FT-0612572, FT-0669047, G0110, G0196, Glycolic acid 100 microg/mL in Acetonitrile, EN300-19242, Glycolic acid, SAJ special grade, >=98.0%, C00160, C03547, D78078, Glycolic acid, Vetec(TM) reagent grade, 98%, HYDROXYACETIC ACID; HYDROXYETHANOIC ACID, Glycolic acid, BioXtra, >=98.0% (titration), Q409373, J-509661, F2191-0224, Hydroxyacetic acid; Hydroxyethanoic acid; Glycollic acid, Z104473274, 287EB351-FF9F-4A67-B4B9-D626406C9B13, Glycolic acid, certified reference material, TraceCERT(R), Glycolic acid, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%, Glycolic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
O7Z, Hydroxyacetic acid, Glycolic acid, Glycolic Acid; Hydroxyacetic Acid; Aceticacid,hydroxy-; acidehydroxyacetique; hydroxyaceticacid; glycolic; AHA
2-HYDROXYACETIC ACID;GLYCOLATE;glycolic;HYDROXYACETIC ACID;HOCH2COOH;GLYCOLLIC ACID;Glycolic acid 70%;GLYCOLIC ACID SIGMAULTRA;glycolate (hydroxyacetate);GLYCOLIC ACID, HIGH PURITY, 70 WT.% SOLU TION IN WATER, 2-Hydroxyacetate, 2-Hydroxyacetic acid, A-Hydroxyacetate, A-Hydroxyacetic acid, Alpha-Hydroxyacetate, Alpha-Hydroxyacetic acid, Glycocide, Glycolate, Glycolic acid, Glycollate, Glycollic acid, GlyPure, GlyPure 70, Hydroxyacetate,
Hydroxyacetic acid, Hydroxyethanoate, Hydroxyethanoic acid, Sodium glycolate, Sodium glycolic acid, α-Hydroxyacetate, α-Hydroxyacetic acid, 2-Hydroxy carboxylate, 2-Hydroxy carboxylic acid, 2-Hydroxyacetate, 2-Hydroxyacetic acid, 2-Hydroxyethanoate, 2-Hydroxyethanoic acid, a-Hydroxyacetate, a-Hydroxyacetic acid, Acetic acid, 2-hydroxy-, Acetic acid, hydroxy- (9CI),



Hydroacetic acid (Glycolic Acid) is an alpha hydroxy acid; used in chemical peels and anti-aging skin products.
Hydroacetic acid (Glycolic Acid) is a type of alpha hydroxy acid (AHA). Alpha hydroxy acids are natural acids found in foods.
Hydroacetic acid (Glycolic Acid) comes from sugarcane.


Don't confuse Hydroacetic acid (Glycolic Acid) with other alpha hydroxy acids, including citric acid, lactic acid, malic acid, and tartaric acid.
These are not the same.
Hydroacetic acid (Glycolic Acid) is an organic substance with the chemical formula C2H4O3.


Hydroacetic acid (Glycolic Acid) is colorless and easily deliquescent crystal.
Hydroacetic acid (Glycolic Acid) is soluble in water, methanol, ethanol, ethyl acetate and other organic solvents, slightly soluble in ether, insoluble in hydrocarbons.


Hydroacetic acid (Glycolic Acid) has the duality of alcohol and acid and decomposes when heated to boiling point.
Hydroacetic acid (Glycolic Acid) is one of the simplest organic compounds, used on a broad scale in contemporary cosmetology and in the chemical industry.
This is because that hydracid has many valuable properties.


Hydroacetic acid (Glycolic Acid) in cosmetics: a regenerating glycol for the face and body.
Industrialists and pharmacists discovered long ago that Hydroacetic acid (Glycolic Acid)s are worth using on the face and skin.
They are ingredients of creams, conditioners, shampoos, ointments and tonics as well as additives in washing gels, exfoliation products, etc.


AHA acids (alpha hydroxyacids) cover various types of popular acids that we use on a daily basis.
Examples include citric, lactic or malic acid.
The AHAs also cover Hydroacetic acid (Glycolic Acid).


Hydroacetic acid (Glycolic Acid) is a solid that excellently absorbs water molecules from the environment.
There are several names denoting Hydroacetic acid (Glycolic Acid): its chemical name is 2-Hydroxyethanoic acid.
That name was introduced by the International Union of Pure and Applied Chemistry (IUPAC) to facilitate the identification of that substance on a global market.


Hydroacetic acid (Glycolic Acid) compound can also be found under the following names: hydroxyacetic acid, alpha-hydroxyacetic acid, hydroxyethanoic acid.
Hydroacetic acid (Glycolic Acid) is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroacetic acid (Glycolic Acid) has a role as a metabolite and a keratolytic drug.


Hydroacetic acid (Glycolic Acid) is a 2-hydroxy monocarboxylic acid and a primary alcohol.
Hydroacetic acid (Glycolic Acid) is functionally related to an acetic acid.
Hydroacetic acid (Glycolic Acid) is a conjugate acid of a glycolate.


Hydroacetic acid (Glycolic Acid) is a metabolite found in or produced by Escherichia coli.
Hydroacetic acid (Glycolic Acid) is the smallest alpha-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid, Hydroacetic acid (Glycolic Acid), is highly soluble in water.


Due to its excellent capability to penetrate the skin, Hydroacetic acid (Glycolic Acid) finds applications in skin care products, most often as a chemical peel.
Hydroacetic acid (Glycolic Acid) may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis.


Once applied, Hydroacetic acid (Glycolic Acid) reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
This allows the outer skin to dissolve revealing the underlying skin.


Hydroacetic acid (Glycolic Acid) is the only domestically produced hydroxyacetic acid.
Hydroacetic acid (Glycolic Acid) is supplied in a 70% chloride-free solution resulting in low corrosivity, making it ideal for a versatile range of cleaning and industrial applications.


Hydroacetic acid (Glycolic Acid) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water.
Hydroacetic acid (Glycolic Acid), also known as hydroxy acetic acid, is one of the alpha-hydroxy acids (AHA’s).
These acids occur naturally in fruits, sugar cane and milk.


When used topically, Hydroacetic acid (Glycolic Acid) can assist with the removal of dead skin cells helping to renew the skin.
Hydroacetic acid (Glycolic Acid) is an organic acid from the family of alpha-hydroxy carboxylic acids that naturally occurs in sugarcane, beets, grapes, and fruits.


Hydroacetic acid (Glycolic Acid) is the first member of the series of alpha-hydroxy carboxylic acids, which means it is one of the smallest organic molecules with both acid and alcohol functionality
Hydroacetic acid (Glycolic Acid) is the smallest α-hydroxy acid (AHA).


This colorless, odorless, and hygroscopic crystalline solid, Hydroacetic acid (Glycolic Acid), is highly soluble in water.
A water solution form is also available.
Hydroacetic acid (Glycolic Acid) is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.


The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.


Hydroacetic acid (Glycolic Acid) is the smallest α-hydroxy acid (AHA).
Hydroacetic acid (Glycolic Acid) appears in the form of a colorless, odorless and hygroscopic crystalline solid that is highly soluble in water and related solvents.


Hydroacetic acid (Glycolic Acid) is associated with sugar-crops and is isolated from sugarcane, sugar beets, pineapple, canteloupe, and unripe grapes.
Hydroacetic acid (Glycolic Acid) is the first member of the series of alpha-hydroxy carboxylic acids, which means it is one of the smallest organic molecules with both acid and alcohol functionality.


Hydroacetic acid (Glycolic Acid) is soluble in water, alcohol, and ether.
Hydroacetic acid (Glycolic Acid) is the smallest alpha-hydroxy acid (AHA).
Hydroacetic acid (Glycolic Acid) is mainly supplemented to various skin-care products to improve the skin’s appearance and texture.


Hydroacetic acid (Glycolic Acid) can also reduce wrinkles, acne scarring, and hyperpigmentation.
Hydroacetic acid (Glycolic Acid) is a colorless, odourless, and hygroscopic crystalline solid with the chemical formula C2H4O3.
Hydroacetic acid (Glycolic Acid) is also known as hydroacetic acid, or 2-hydroxyethanoic acid, and its IUPAC name is hydroxyacetic acid.


Hydroacetic acid (Glycolic Acid) is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroacetic acid (Glycolic Acid) is an alpha hydroxy acid that has antibacterial, antioxidant, keratolytic, and anti-inflammatory properties.
Hydroacetic acid (Glycolic Acid) is functionally related to acetic acid and is slightly stronger than it.


The salts or esters of glycolic acid are called glycolates.
Hydroacetic acid (Glycolic Acid) is widespread in nature and can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.


Hydroacetic acid (Glycolic Acid) is a routine essential.
Hydroacetic acid (Glycolic Acid) can be found amongst our exfoliating, fine line fighting beauty products – it’s nothing new but that doesn’t mean it doesn’t deserve a shoutout for being a damn powerhouse.


Hydroacetic acid (Glycolic Acid) is an AHA, aka alpha hydroxy acid.
Some other acids that fall under the Hydroacetic acid (Glycolic Acid) umbrella include lactic and citric acids.
Hydroacetic acid (Glycolic Acid)’s are usually derived from natural sources; lactic from milk, citric from citrus and glycolic from sugarcane, pineapple, canteloupe or unripe grapes.


Hydroacetic acid (Glycolic Acid)’s are not only beneficial when applied topically but due to their molecular size (teeny tiny), they’re pretty good at getting under the skin and putting in the extra effort from the inside too.
You will commonly find Hydroacetic acid (Glycolic Acid) in your cleansers, toners, exfoliants, and collagen stimulating products.


Hydroacetic acid (Glycolic Acid) is an α-hydroxy acid.
Hydroacetic acid (Glycolic Acid) solutions having concentration of 70% and pH range of 0.08 to 2.75 are widely employed as superficial chemical peeling agents.


Various oligomers or polymers of lactic and/or Hydroacetic acid (Glycolic Acid) (low molecular weight) have been prepared.
Hydroacetic acid (Glycolic Acid) can be determined via plant tissue coupled flow injection chemiluminescence biosensors, which can be used both as a plant-tissue based biosensor and chemiluminescence flow sensor.


Hydroacetic acid (Glycolic Acid) is a naturally occurring alpha hydroxy acids (or AHAs).
Hydroacetic acid (Glycolic Acid) is a type of alpha hydroxy acid (AHA) made from sugar cane that can act like a water-binding agent.
Glycolic is the most researched and purchased type of alpha hydroxy acid on the market that has all its effects backed up by studies.


Hydroacetic acid (Glycolic Acid); chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest α-hydroxy acid (AHA).
Hydroacetic acid (Glycolic Acid) is the smallest alpha-hydroxy acid.
Hydroacetic acid (Glycolic Acid) solution is a useful solution of acid.


Hydroacetic acid (Glycolic Acid) is a useful intermediate for synthesis.
The most useful synthesis use is for oxidation reduction esterification and long chain polymerization.
Hydroacetic acid (Glycolic Acid), also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.


These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroacetic acid (Glycolic Acid) is an extremely weak basic (essentially neutral) compound (based on its pKa).
Hydroacetic acid (Glycolic Acid) exists in all living species, ranging from bacteria to humans.


In humans, Hydroacetic acid (Glycolic Acid) is involved in rosiglitazone metabolism pathway.
Outside of the human body, Hydroacetic acid (Glycolic Acid) has been detected, but not quantified in, several different foods, such as sourdocks, pineappple sages, celeriacs, cloves, and feijoa.


This could make Hydroacetic acid (Glycolic Acid) a potential biomarker for the consumption of these foods.
Once applied, Hydroacetic acid (Glycolic Acid) reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.


Hydroacetic acid (Glycolic Acid) is a potentially toxic compound.
Hydroacetic acid (Glycolic Acid), with regard to humans, has been found to be associated with several diseases such as transurethral resection of the prostate and biliary atresia; glycolic acid has also been linked to several inborn metabolic disorders including glutaric acidemia type 2, glycolic aciduria, and d-2-hydroxyglutaric aciduria.


Hydroacetic acid (Glycolic Acid) and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis.
Hydroacetic acid (Glycolic Acid), also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.


These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroacetic acid (Glycolic Acid) is an extremely weak basic (essentially neutral) compound (based on its pKa).
Hydroacetic acid (Glycolic Acid) exists in all living species, ranging from bacteria to humans.


Hydroacetic acid (Glycolic Acid); chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest α-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid, Hydroacetic acid (Glycolic Acid), is highly soluble in water.


Hydroacetic acid (Glycolic Acid) 99% crystals reagent is a highly pure form of glycolic acid that is commonly used in various industries, including cosmetics, pharmaceuticals, and chemical manufacturing.
Hydroacetic acid (Glycolic Acid) is known for its ability to exfoliate and improve skin texture, making it a popular ingredient in skincare products.



USES and APPLICATIONS of HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is used to evaluate the efficacy of glycolic peels treatment for all types of acne.
Hydroacetic acid (Glycolic Acid) is used in the fine synthesis of medicine and as a raw material of cosmetics and organic synthesis.
Hydroacetic acid (Glycolic Acid) can be used as an exfoliant if concentrated properly at 5%.


Hydroacetic acid (Glycolic Acid) can help shed dead skin and renew surface skin, improving visible signs of ageing, such as uneven skin tone, sun damage, fine lines, rough or patchy skin, and vastly reduce the size of wrinkles.
To obtain all these benefits you will need a leave-on AHA exfoliator which is 5%-10% Hydroacetic acid (Glycolic Acid) that is formulated at a pH level of 3-4 and then the product must be rinsed off thoroughly.


Hydroacetic acid (Glycolic Acid) is not only a popular ingredient in skincare products, it is also used in the textile industry and in food processing as a flavoring agent and a preservative.
Hydroacetic acid (Glycolic Acid) is used Facial care (exfoliating products, peelings, purifying creams and lotions, cleansing gels, radiance masks, eye contour creams, anti-imperfections care, beard creams, unifying care).


Hydroacetic acid (Glycolic Acid) is used Body care (body milks, shower gels).
Hydroacetic acid (Glycolic Acid) is used Hair care (anti-dandruff shampoos, purifying hair masks).
Alpha hydroxy acids like Hydroacetic acid (Glycolic Acid) work by removing the top layers of dead skin cells.


Hydroacetic acid (Glycolic Acid) also seems to help reverse sun damage to the skin.
People use Hydroacetic acid (Glycolic Acid) for acne, aging skin, dark skin patches on the face, and acne scars.
Hydroacetic acid (Glycolic Acid) is also used for stretch marks and other conditions, but there is no good scientific evidence to support these other uses.


Uses of Hydroacetic acid (Glycolic Acid): Acid Cleaners, Concrete Cleaners, Food Processing, Hard Surface Cleaners, Leather-Dyeing and Tanning, Petroleum Refining, Textile, and Water Treatment.
Textiles uses of Hydroacetic acid (Glycolic Acid): In addition to Hydroacetic acid (Glycolic Acid) acne products, the chemical is an excellent product for the textile industry, where it is used for dyeing and tanning purposes.


Food: One of the key Hydroacetic acid (Glycolic Acid) benefits is that it works as a flavor enhancer and food preservative.
Hydroacetic acid (Glycolic Acid) is used in the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.


Hydroacetic acid (Glycolic Acid) reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles.
Hydroacetic acid (Glycolic Acid) acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells.


Hydroacetic acid (Glycolic Acid) also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water.
This occurs in the cellular cement through an activation of Hydroacetic acid (Glycolic Acid) and the skin’s own hyaluronic acid content.
Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by Hydroacetic acid (Glycolic Acid).


As a result, the skin’s own ability to raise Hydroacetic acid (Glycolic Acid)'s moisture content is increased.
Hydroacetic acid (Glycolic Acid) is the simplest alpha hydroxyacid (AHA).
Hydroacetic acid (Glycolic Acid) is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight.


Hydroacetic acid (Glycolic Acid) is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH.
Hydroacetic acid (Glycolic Acid) proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes.


Hydroacetic acid (Glycolic Acid) is also used for diminishing the signs of age spots, as well as actinic keratosis.
However, Hydroacetic acid (Glycolic Acid) is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles.


Regardless of the G skin type, Hydroacetic acid (Glycolic Acid) use is associated with softer, smoother, healthier, and younger looking skin.
Hydroacetic acid (Glycolic Acid) is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.
Hydroacetic acid (Glycolic Acid) is also an excellent alternative to toxic and low penetration acids such as sulfuric, phosphoric, and sulfamic in cleaners, water treatment chemicals, and O&G applications.


Hydroacetic acid (Glycolic Acid) is preffered nowadays due to its high speed of action, scale removal performance, less corrosivity, biodegredability, and less hazardous waste stream.
Personal and Skincare Products uses of Hydroacetic acid (Glycolic Acid): ​Anti-aging creams, acne treatments, exfoliating scrubs, hair conditioners, and other hair care products.


Household, Institutional, and Industrial Cleaning Products uses of Hydroacetic acid (Glycolic Acid): Hard surface cleaners, metal cleaners, toilet bowl cleaners, and laundry sours.
Water Treatment Applications of Hydroacetic acid (Glycolic Acid): Boiler cleaning chemicals, well stimulating solutions, and process cleaning products.


Electronics and Metal Surface Treatment uses of Hydroacetic acid (Glycolic Acid): Etching chemicals, printed circuit board fluxes, electropolishing chemicals, and metal surface preparations.
Oil and Gas Applications of Hydroacetic acid (Glycolic Acid): Oil drilling chemicals, well stimulation, mid-and downstream descalers, and general process scale removers.


Hydroacetic acid (Glycolic Acid) is used for organic synthesis, etc
Industries: Adhesives | Building & Construction | Care Chemicals | Energy | Inks | Maintenance, Repair, Overhaul | Metal Processing & Fabrication | Transportation | Water Treatment


Formulations based on that acid are also used in beauty salons as part of rejuvenating treatments.
Hydroacetic acid (Glycolic Acid) is used in the textile industry as a dyeing and tanning agent.
Cleaning and washing concentrates with Hydroacetic acid (Glycolic Acid) quickly remove dirt and microbes from different surfaces.


This is why they are widely used in private homes, industrial plants and public facilities.
Hydroacetic acid (Glycolic Acid) is also desired by entities from the food, logistic and catering industries.
Hydroacetic acid (Glycolic Acid) can also be found at schools and kindergartens.


Hydroacetic acid (Glycolic Acid) is used in various skin-care products.
Hydroacetic acid (Glycolic Acid) is widespread in nature.
A glycolate (sometimes spelled "glycollate") is a salt or ester of Hydroacetic acid (Glycolic Acid).


Cleaning: Hydroacetic acid (Glycolic Acid) and hydroxyacetic acid are excellent cleaning agents for such surfaces as concrete and metal.
Adhesives: Hydroacetic acid (Glycolic Acid) is commonly used in various adhesives and plastics.
Hydroacetic acid (Glycolic Acid) has significant whitening and activating effect, can promote cell metabolism, remove dead skin and dissolve cutin.


Hydroacetic acid (Glycolic Acid) can soften the skin, make the skin soft, smooth, delicate, elastic and shiny.
Hydroacetic acid (Glycolic Acid) can be used as a synergist of freckle, wrinkle and acne products to promote and increase the efficiency of products.
Hydroacetic acid (Glycolic Acid) is a raw material for organic synthesis and can be used to produce ethylene glycol.


Hydroacetic acid (Glycolic Acid) can also be used as chemical analysis reagent.
Hydroacetic acid (Glycolic Acid) can be used as cleaning agent, which has low corrosivity to materials, and will not precipitate organic acid iron during cleaning.


Hydroacetic acid (Glycolic Acid) can be used in organic synthesis and printing and dyeing industry.
Hydroacetic acid (Glycolic Acid) can be used for sterilization of soap.
Hydroacetic acid (Glycolic Acid) can be used as a complexing agent for electroless nickel plating to improve the coating quality, and can also be used as an additive for other electroplating or electroless plating


Available in various quantities, Hydroacetic acid (Glycolic Acid) is used as a dyeing and tanning agent, a flavoring agent and preservative, an intermediate for organic synthesis, etc.
Hydroacetic acid (Glycolic Acid) is most commonly used for hyperpigmentation, fine lines and acne.


Hydroacetic acid (Glycolic Acid) is mostly found in exfoliating products (peels), or in creams and lotions but at a much lower concentration. Hydroacetic acid (Glycolic Acid) is obtained by synthesis.
Hydroacetic acid (Glycolic Acid) is an acid and should never be used undiluted.


Hydroacetic acid (Glycolic Acid) is classed as an advanced skincare ingredient and should not be used unless you understand the usage and applications of Glycolic Acid.
Glycolic is a commonly known ingredient in the personal care and cosmetics market and Hydroacetic acid (Glycolic Acid) is also widely used in several household and industrial cleaning applications.


Hydroacetic acid (Glycolic Acid) is commonly used in chemical milling, cleaning, and polishing of metals, and in copper pickling solutions. Hydroacetic acid (Glycolic Acid) is also used in the cosmetic industry in skin peels.
Hydroacetic acid (Glycolic Acid) is a naturally occurring alpha hydroxy Hydroacetic acid (Glycolic Acid) is very useful in exfoliating products as alpha-hydroxy acid peel, or in creams & lotions at a lower concentration for a more gentle acid-based peel.


Hydroacetic acid (Glycolic Acid) is widely used to rejuvenate the skin by encouraging the shedding of old surface skin cells.
Hydroacetic acid (Glycolic Acid) is used in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent.


Hydroacetic acid (Glycolic Acid) is also used in adhesives and plastics.
Hydroacetic acid (Glycolic Acid) is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.


Hydroacetic acid (Glycolic Acid) is used in surface treatment products that increase the coefficient of friction on tile flooring.
Hydroacetic acid (Glycolic Acid) is the active ingredient in the household cleaning liquid Pine-Sol.
In textile industry, Hydroacetic acid (Glycolic Acid) can be used as a dyeing and tanning agent.


Hydroacetic acid (Glycolic Acid) can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.
Hydroacetic acid (Glycolic Acid) can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss.
Moreover, Hydroacetic acid (Glycolic Acid) is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.


Due to its excellent capability to penetrate skin, Hydroacetic acid (Glycolic Acid) finds applications in skin care products, most often as a chemical peel performed by a dermatologist in concentrations of 20%-80% or at-home kits in lower concentrations of 10%.
Hydroacetic acid (Glycolic Acid) is used to improve the skin's appearance and texture.


Hydroacetic acid (Glycolic Acid) may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions.
Once applied, Hydroacetic acid (Glycolic Acid) reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.


This allows the outer skin to "dissolve" revealing the underlying skin.
Hydroacetic acid (Glycolic Acid) is also a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.


Hydroacetic acid (Glycolic Acid) is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).
Among other uses Hydroacetic acid (Glycolic Acid) finds employment in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative.


Hydroacetic acid (Glycolic Acid) is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.
Hydroacetic acid (Glycolic Acid) is used in the textile industry as a dyeing and tanning agent.


Hydroacetic acid (Glycolic Acid) is widely used in skin care products as an exfoliant and keratolytic.
Hydroacetic acid (Glycolic Acid) is used in the textile industry as a dyeing and tanning agent.
Hydroacetic acid (Glycolic Acid) is used in the processing of textiles, leather, and metals.


Hydroacetic acid (Glycolic Acid) was once most commonly used as a chemical peel by dermatologists, this was because out of all AHAs, glycolic has the lowest molecular weight, meaning it has the ability to penetrate the skin even deeper than most other AHAs, making it more effective when it comes to reducing wrinkles, acne scarring, hyperpigmentation and improving other skin conditions.


Due to its excellent capability to penetrate skin, Hydroacetic acid (Glycolic Acid) is often used in skin care products, most often as a chemical peel.
Hydroacetic acid (Glycolic Acid) is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
Hydroacetic acid (Glycolic Acid) is the most commonly used natural AHA (= alpha hydroxy acid).


Hydroacetic acid (Glycolic Acid) is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroacetic acid (Glycolic Acid) is extracted from sugar cane, grapes and wine leaves.


Typical use level of Hydroacetic acid (Glycolic Acid) is between 1-20% (final concentration of glycolic acid).
For making a 10% AHA peel, use about 14.5% of Hydroacetic acid (Glycolic Acid), making a 5% AHA peel, use about 7.2%.
For home use, Hydroacetic acid (Glycolic Acid) is not recommended to make AHA peels higher than 20% (equals about 28.5% of glycolic acid).


Hydroacetic acid (Glycolic Acid) is used Peels, creams, lotions, masks, cleansers.
Due to Hydroacetic acid (Glycolic Acid)'s acidity the final product needs to be tested for safe pH.
Optimal pH range of Hydroacetic acid (Glycolic Acid) is from 3.5-5.0.


Some over the counter products, after adding Hydroacetic acid (Glycolic Acid), will separate as a result of the low pH, and need to be stabilized.
Hydroacetic acid (Glycolic Acid) has been used in the preparation of PLGA-PEG-PLGA copolymer (PLGA = poly(lactic/glycolic, PEG = polyethylene glycol).
Hydroacetic acid (Glycolic Acid) is used as a monomer to create PLGA and other biocompatible copolymers.


Hydroacetic acid (Glycolic Acid) is often useful for dyeing and tanning, and is often included in emulsion polymers, solvents and additives for ink and paint.
Hydroacetic acid (Glycolic Acid) is metabolized by cells in vitro to become oxalic acid which kills cells.


Hydroacetic acid (Glycolic Acid) is synthesized many ways but is often isolated from sugarcane, pineapples and other acidic tasting fruits.
Hydroacetic acid (Glycolic Acid) is the smallest alpha-hydroxy acid (AHA).
In its pure form, Hydroacetic acid (Glycolic Acid) is a colorless crystalline solid.


Due to its excellent capability to penetrate skin, Hydroacetic acid (Glycolic Acid) finds applications in skin care products, most often as a chemical peel.
Hydroacetic acid (Glycolic Acid) is also used for tattoo removal.
In E coli Hydroacetic acid (Glycolic Acid) is involved in glyoxylate and dicarboxylate metabolism.


Additionally, Hydroacetic acid (Glycolic Acid) is used in the production of various chemicals, such as polymers and esters, and as a pH adjuster in various formulations.
Its high purity and effectiveness make Hydroacetic acid (Glycolic Acid) a valuable tool in many applications.


-Applications of Hydroacetic acid (Glycolic Acid)
Today’s drug or household chemical stores offer various types of agents and formulations containing Hydroacetic acid (Glycolic Acid).
Their application is very wide.

Hydroxyacetic acid is a component of:
*concentrates designed for the cleaning of Gres tiles, joints and porous surfaces,
*specialised preparations for washing and sterilizing tanks, cisterns, *production lines or equipment having contact with food,
*liquids used for cleaning public sanitary facilities.


-Skin care uses of Hydroacetic acid (Glycolic Acid):
Dermatologists commonly use Hydroacetic acid (Glycolic Acid) for acne treatment and other skin condition.
Hydroacetic acid (Glycolic Acid) skin care products are made to safely penetrate skin to exfoliate skin, reduce scarring from acne and reduce wrinkling.



FUNCTIONS OF HYDROACETIC ACID (GLYCOLIC ACID):
*The 70% solution can be used as cleaning agent.
*The 99.5% Crystal can be used in the fine synthesis of medicine.
*Hydroacetic acid (Glycolic Acid) is used as ingredient of cosmetics, adhesives, petroleum emulsion splitter, soldering paster and coatings.



CHEMICAL PROPERTIES OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid), CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF).
Hydroacetic acid (Glycolic Acid) is soluble in water,alcohol,and ether.
Hydroacetic acid (Glycolic Acid) is used in dyeing, tanning, electropolishing,and in foodstuffs.
Hydroacetic acid (Glycolic Acid) is produced by oxidizing glycol with dilute nitric acid.



PRODUCTION METHOD OF HYDROACETIC ACID (GLYCOLIC ACID):
The contemporary cosmetic and chemical markets would be hard to imagine without substances such as AHAs, including Hydroacetic acid (Glycolic Acid). What is this semi-finished product made of?
For decades, various methods of producing Hydroacetic acid (Glycolic Acid) were developed.

Hydroacetic acid (Glycolic Acid) can be obtained, for example, by:
A reaction of acetic (chloroacetic) acid derivative with sodium hydroxide (NaOH), which is a strong base.
Obviously, Hydroacetic acid (Glycolic Acid) will not be produced immediately.

The production of Hydroacetic acid (Glycolic Acid) is only possible if the environment of both reacting ingredients is acidified.
A reaction of formaldehyde with water gas (it is one of the most popular methods of the mass production of Hydroacetic acid (Glycolic Acid); however, the acquisition of the semi-finished product with this method generates a lot of waste).



CHEMICAL AND STRUCTURAL FORMULAS OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid)'structural formula is the following: HOCH2COOH.
The molecular formula of Hydroacetic acid (Glycolic Acid) is: C2H4O3.
Both formulas indicate that Hydroacetic acid (Glycolic Acid) contains both carboxyl and the hydroxyl groups, which are typical of alpha-hydroxyacids.



OCCURRENCE OF HYDROACETIC ACID (GLYCOLIC ACID):
Plants produce Hydroacetic acid (Glycolic Acid) during photorespiration.
Hydroacetic acid (Glycolic Acid) is recycled by conversion to glycine within the peroxisomes and to tartronic acid semialdehyde within the chloroplasts.



HOW TO RECOGNISE HYDROACETIC ACID (GLYCOLIC ACID)?
The characteristics of that Hydroacetic acid (Glycolic Acid) are as follows: it is a solid having the form of a white or transparent, crystalline, odourless powder.
Hydroacetic acid (Glycolic Acid) decomposes at 100°C and melts at 80°C.
It is assumed that Hydroacetic acid (Glycolic Acid) has a density of 1.49 g/cm³ at around 25°C.



WHAT ELSE DISTINGUISHES HYDROACETIC ACID (GLYCOLIC ACID)?
The water solubility of Hydroacetic acid (Glycolic Acid) is very good and largely depends on the temperature of the liquid: the higher it is, the better the powder will dissolve to form a solution.
Hydroacetic acid (Glycolic Acid) can also be dissolved in alcohols: ethanol, methanol or acetone.
Hydroacetic acid (Glycolic Acid) reacts with aluminium and oxidants, which may even cause ignition.



OPINIONS OF HYDROACETIC ACID (GLYCOLIC ACID):
Contemporary consumers search for proven, high-quality chemicals that bring rapid effects and do not cause allergies.
People are increasingly eager to choose natural Hydroacetic acid (Glycolic Acid) and use cosmetics and chemicals which contain that ingredient.
Hydroacetic acid (Glycolic Acid), designed for professional use, is globally recognised as a substitute of many other acids produced artificially.
Industrial plants use C2H4O3, for example, instead of Hydroacetic acid (Glycolic Acid) which, once used, turns into highly poisonous and hazardous waste.



WHY IS HYDROACETIC ACID (GLYCOLIC ACID) INCREASINGLY POPULAR?
Hydroacetic acid (Glycolic Acid)'s effects can be noticed within a few days.
With that Hydroacetic acid (Glycolic Acid), the epidermis regenerates faster and recovers its natural colour and flexibility.
Hydroacetic acid (Glycolic Acid) can also be used against discolouration, inflammatory conditions and scars.
Amongst cosmetic ingredients, we can find it under the INCI name Hydroacetic acid (Glycolic Acid).



HISTORY OF HYDROACETIC ACID (GLYCOLIC ACID):
The name "Hydroacetic acid (Glycolic Acid)" was coined in 1848 by French chemist Auguste Laurent (1807–1853).
He proposed that the amino acid glycine—which was then called glycocolle—might be the amine of a hypothetical acid, which he called "Hydroacetic acid (Glycolic Acid)" (acide glycolique).

Hydroacetic acid (Glycolic Acid) was first prepared in 1851 by German chemist Adolph Strecker (1822–1871) and Russian chemist Nikolai Nikolaevich Sokolov (1826–1877).
They produced it by treating hippuric acid with nitric acid and nitrogen dioxide to form an ester of benzoic acid and Hydroacetic acid (Glycolic Acid) (C6H5C(=O)OCH2COOH), which they called "benzoglycolic acid" (Benzoglykolsäure; also benzoyl glycolic acid).
They boiled the ester for days with dilute sulfuric acid, thereby obtaining benzoic acid and Hydroacetic acid (Glycolic Acid) (Glykolsäure).



PREPARATION OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) can be synthesized in various ways.
The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.
Hydroacetic acid (Glycolic Acid) is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.

Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.
Some of today's Hydroacetic acid (Glycolic Acid)s are formic acid-free.
Hydroacetic acid (Glycolic Acid) can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.
Hydroacetic acid (Glycolic Acid) can also be prepared using an enzymatic biochemical process that may require less energy.



PROPERTIES OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions, forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of Hydroacetic acid (Glycolic Acid)'s proton.



PREPARATION OF HYDROACETIC ACID (GLYCOLIC ACID):
There are different preparation methods to synthesize Hydroacetic acid (Glycolic Acid).
However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less.

Hydroacetic acid (Glycolic Acid) can be prepared when chloroacetic acid reacts with sodium hydroxide and undergoes re-acidification. Electrolytic reduction of oxalic acid also could synthesize this compound.
Hydroacetic acid (Glycolic Acid) can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroacetic acid (Glycolic Acid) can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.



BENEFITS OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.



ORGANIC SYNTHESIS OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.
Hydroacetic acid (Glycolic Acid) is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).

Commercially, important derivatives include the methyl (CAS# 96-35-5) and ethyl (CAS# 623-50-7) esters which are readily distillable (boiling points 147–149 °C and 158–159 °C, respectively), unlike the parent acid.
The butyl ester (b.p. 178–186 °C) is a component of some varnishes, being desirable because it is nonvolatile and has good dissolving properties.



ALTERNATIVE PARENTS OF HYDROACETIC ACID (GLYCOLIC ACID):
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Primary alcohols
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF HYDROACETIC ACID (GLYCOLIC ACID):
*Alpha-hydroxy acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Primary alcohol
*Organooxygen compound
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound



PREPARATION OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is isolated from natural sources and is inexpensively available.
Hydroacetic acid (Glycolic Acid) can be prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Hydroacetic acid (Glycolic Acid) can also be prepared using an enzymatic biochemical process which produces fewer impurities compared to traditional chemical synthesis, requires less energy in production and produces less co-product.



CHEMICAL PROPERTIES OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroacetic acid (Glycolic Acid) is used as a monomer in the preparation of Poly(lactic-co-glycolic acid) (PLGA).
Hydroacetic acid (Glycolic Acid) reacts with lactic acid to form PLGA using ring-opening co-polymerization.
Polyglycolic acid (PGA) is prepared from the monomer Hydroacetic acid (Glycolic Acid) using polycondensation or ring-opening polymerization.



THE BENEFITS OF HYDROACETIC ACID (GLYCOLIC ACID):
Exfoliates dead skin cells to reveal softer, smoother skin
- Hydroacetic acid (Glycolic Acid) works by loosening the binding between dead skin cells, allowing them to slough off.

Reduces acne:
- by encouraging the shedding or peeling of cells on the skin's surface and lining the pores, Hydroacetic acid (Glycolic Acid) prevents the formation of clogged pores—it also has antibacterial and anti-inflammatory properties.

Stimulates collagen production from within:
- Hydroacetic acid (Glycolic Acid)'s work on the skin's deeper layers to boost collagen production.
You will notice smooth skin almost immediately however Hydroacetic acid (Glycolic Acid) can take a wee bit of time to notice an improvement in those fine lines and wrinkles.



PREPARATION OF HYDROACETIC ACID (GLYCOLIC ACID):
There are different preparation methods to synthesize Hydroacetic acid (Glycolic Acid).
However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less.
Hydroacetic acid (Glycolic Acid) can be produced when chloroacetic acid reacts with sodium hydroxide and then undergoes re-acidification.
Hydroacetic acid (Glycolic Acid) can also be synthesized by electrolytic reduction of oxalic acid.
Hydroacetic acid (Glycolic Acid) can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroacetic acid (Glycolic Acid) can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.



CHEMICAL, HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid), due to its OH group, reacts with hydrogen halides, such as hydrogen chloride, to give their respective monohaloacetic acid, in this case chloroacetic acid.
Hydroacetic acid (Glycolic Acid) is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.

The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.



PHYSICAL, HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is a colorless solid, very soluble in water.
Hydroacetic acid (Glycolic Acid) is odorless.



BENEFITS OF HYDROACETIC ACID (GLYCOLIC ACID):
*Hydroacetic acid (Glycolic Acid) can reduce the appearance of fine lines, irregular pigmentation, age spots & decreases enlarged pores
*Hydroacetic acid (Glycolic Acid) is very useful in exfoliating products as alpha-hydroxy acid peel, or in creams & lotions at a lower concentration for a more gentle acid-based peel
*Hydroacetic acid (Glycolic Acid) is widely used to rejuvenate the skin by encouraging the shedding of old surface skin cells



PREPARATION OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is often prepared by the reaction of chloroacetic acid with sodium hydroxide, followed by re-acidification.
Cl-CH2COOH + 2 NaOH → OH-CH2COONa + NaCl + H2O
OH-CH2COONa + HCl → OH-CH2COOH + NaCl

Another route involves the reaction of potassium cyanide with formaldehyde.
The resulting potassium glycolate is treated with acid and purified.
Hydroacetic acid (Glycolic Acid) was historically first prepared by treating hippuric acid with nitric acid and nitrogen dioxide.

This forms and ester of benzoic acid and Hydroacetic acid (Glycolic Acid), which is hydrolyzed to glycolic acid by boiling it in sulfuric acid.
Hydrogenation of oxalic acid is another route.
Hydroacetic acid (Glycolic Acid) can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.



INCORPORATING HYDROACETIC ACID (GLYCOLIC ACID) INTO YOUR DAILY REGIME
All skin types can tolerate the use of Hydroacetic acid (Glycolic Acid); it’s best suited to acne-prone or oily skin



SCIENTIFIC FACTS OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) and Lactic Acid are alpha hydroxy acids (AHAs).
They may be either naturally occurring or synthetic.
They are often found in products intended to improve the overall look and feel of the skin.
Hydroacetic acid (Glycolic Acid) is the most widely used of out of the group and is usually manufactured from sugar cane.
Lactic acid, derived primarily from milk and its origins can be traced back to Cleopatra, who purportedly used sour milk on her skin.



WHAT IS HYDROACETIC ACID (GLYCOLIC ACID)?
Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs.
The salts of Hydroacetic acid (Glycolic Acid) (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu
Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products.
In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products.



HYDROACETIC ACID (GLYCOLIC ACID) VS. INORGANIC ACIDS:
Hydroacetic acid (Glycolic Acid) has been replacing mineral acids in multiple applications to avoid the high corrosivity and toxicity of strong inorganic acids.
Hydroacetic acid (Glycolic Acid) is commonly used in concrete and masonry cleaners, replacing the long hydrochloric history in this application.
The high penetration and limited damage to the metal surfaces and truck beds make Hydroacetic acid (Glycolic Acid) a better option than mineral acids in such applications.



HYDROACETIC ACID (GLYCOLIC ACID) VS. ORGANIC ACIDS:
Hydroacetic acid (Glycolic Acid) has the smallest molecule of the Alpha Hydroxy Acids (AHA) family, so it offers deeper penetration and works faster than other organic acids, including lactic, citric, and maleic acids.

Hydroacetic acid (Glycolic Acid) is also preferred over many Beta Hydroxy Acids (BHA) as it provides improved skin moisturization and reduces the visible signs of sun damage and aging wrinkles.
Hydroacetic acid (Glycolic Acid) is an excellent choice to replace citric, formic, and acetic acids in industrial applications due to its rapid descaling efficacy combined with superior chelation performance.



CHEMISTRY PROFILE OF HYDROACETIC ACID (GLYCOLIC ACID):
Hydroacetic acid (Glycolic Acid) is a green acid that is readily biodegradable, VOC-free, and less corrosive than inorganic acids and many other organic acids.



BIODEGRADABLE HYDROACETIC ACID (GLYCOLIC ACID): OPINIONS AND BENEFITS:
Many manufacturers believe that powdered Hydroacetic acid (Glycolic Acid), derived from natural sources, is an excellent alternative to aggressive chemicals.
Hydroacetic acid (Glycolic Acid) has a very broad range of application; when used in appropriate proportions and conditions, it is not harmful to humans or the environment.

In addition, biodegradable Hydroacetic acid (Glycolic Acid) for the face, or a cleaning fluid containing that ingredient, do not increase the amount of toxic waste.
They are only made of raw materials of natural origin, which quickly decompose under the influence of micro-organisms.
Vegetable waste remaining after production can be converted, for example, into compost without occupying any additional space for landfills.



PHYSICAL and CHEMICAL PROPERTIES of HYDROACETIC ACID (GLYCOLIC ACID):
Molecular Weight: 76.05 g/mol
XLogP3: -1.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 76.016043985 g/mol
Monoisotopic Mass: 76.016043985 g/mol
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 40.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 112 °C (1013 hPa)
Density: 1.26 g/cm3 (20 °C)
Melting Point: 10 °C
pH value: 0.5 (700 g/l, H₂O, 20 °C)
Vapor pressure: 27.5 hPa (25 °C)
Color: colorless liquid
Assay (acidimetric): 69.0 - 74.0 %
Density: (d 20 °C/ 4 °C) 1.260 - 1.280
Heavy metals (as Pb): ≤ 3 ppm
Refractive index (n 20°/D): 1.410 - 1.415
pH-value: 0.0 - 1.0

Chemical formula: C2H4O3
Molar mass: 76.05 g/mol
Appearance: White powder or colorless crystals
Density: 1.49 g/cm3
Melting point: 75 °C (167 °F; 348 K)
Boiling point: Decomposes
Solubility in water: 70% solution
Solubility in other solvents: Alcohols, acetone,
acetic acid and ethyl acetate
log P: −1.05
Acidity (pKa): 3.83

Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 10 °C
Initial boiling point and boiling range 112 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,25 g/mL at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none

Other safety information: No data available
Product name: Glycolic Acid
Other name: Hydroxyacetic Acid
EINECS: 201-180-5
Boiling Point: 112 °C
Purity: 99% White crystal; 70% Yellowish solution
Sample: Free
CAS number: 79-14-1
EC number: 201-180-5
Hill Formula: C₂H₄O₃
Chemical formula: HOCH₂COOH
Molar Mass: 76.05 g/mol

HS Code: 2918 19 98
Boiling point: 100 °C (decomposition)
Density: 1.49 g/cm3 (25 °C)
Flash point: >300 °C (decomposition)
Melting Point: 78 - 80 °C
pH value: 2 (50 g/l, H₂O, 20 °C)
Vapor pressure: 0.00093 hPa (25 °C)
Bulk density: 600 kg/m3
Melting point: 75-80 °C (lit.)
Boiling point: 112 °C
Density: 1.25 g/mL at 25 °C
vapor pressure: 10.8 hPa (80 °C)

refractive index: n20/D 1.424
Flash point: 112°C
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear
pka: 3.83(at 25℃)
form: Solution
color: White to off-white
PH: 2 (50g/l, H2O, 20℃)
Odor: at 100.00 %. odorless very mild buttery
Odor Type: buttery
Viscosity: 6.149mm2/s

Water Solubility: SOLUBLE
Sensitive: Hygroscopic
Merck: 14,4498
BRN: 1209322
Stability: Stable.
Incompatible with bases, oxidizing agents and reducing agents.
InChIKey: AEMRFAOFKBGASW-UHFFFAOYSA-N
LogP: -1.07 at 20℃
Indirect Additives used in Food Contact Substances: GLYCOLIC ACID
FDA 21 CFR: 175.105
CAS DataBase Reference: 79-14-1(CAS DataBase Reference)
EWG's Food Scores: 1-4
NCI Dictionary of Cancer Terms: glycolic acid
FDA UNII: 0WT12SX38S
NIST Chemistry Reference: Acetic acid, hydroxy-(79-14-1)

EPA Substance Registry System: Glycolic acid (79-14-1)
Pesticides Freedom of Information Act (FOIA): Glycolic Acid
Melting Point: 10.0°C
Boiling Point: 113.0°C
Color: Yellow
Linear Formula: CH2OHCOOH
Formula Weight: 76.04
Percent Purity: 70%
Density: 1.2700 g/mL
Physical Form: Solution
Specific Gravity: 1.27
Chemical Name or Material: Glycolic acid, 70% in water

Chemical Formula: C2H4O3
Weight: Average: 76.0514
Monoisotopic: 76.016043994
InChI Key: AEMRFAOFKBGASW-UHFFFAOYSA-N
InChI: InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
CAS number: 79-14-1
IUPAC Name: 2-hydroxyacetic acid
Traditional IUPAC Name: glycolic acid
SMILES: OCC(O)=O
Water Solubility: 608 g/L
logP: -1
logP: -1
logS: 0.9

pKa (Strongest Acidic): 3.53
pKa (Strongest Basic): -3.6
Physiological Charge: -1
Hydrogen Acceptor Count: 3
Hydrogen Donor Count: 2
Polar Surface Area: 57.53 Ų
Rotatable Bond Count: 1
Refractivity: 14.35 m³·mol⁻¹
Polarizability: 6.2 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes



FIRST AID MEASURES of HYDROACETIC ACID (GLYCOLIC ACID):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROACETIC ACID (GLYCOLIC ACID):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROACETIC ACID (GLYCOLIC ACID):
-Extinguishing media:
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROACETIC ACID (GLYCOLIC ACID):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROACETIC ACID (GLYCOLIC ACID):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage class:
Storage class (TRGS 510): 8B: Non-combustible,



STABILITY and REACTIVITY of HYDROACETIC ACID (GLYCOLIC ACID):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


HYDROCARBON RESIN C9
HYDROCARBON RESIN C9 Hydrocarbon Resin C9 LESTAC-P Seires Light to Yellow Color Hydrocarbon Resin C9 aromatic petroleum resin is a kind of internal plasticizing resin produced by Hydrocarbon Resin C9 fraction, by- products of petroleum cracking, through pretreatment, catalysis or thermal polymerization and distillation, mainly used in rubber, Tyre, Painting ...... Description: LESTAC-P Seires Light to Yellow Color Hydrocarbon Resin C9 aromatic petroleum resin is a kind of internal plasticizing resin produced by Hydrocarbon Resin C9 fraction, by- products of petroleum cracking, through pretreatment, catalysis or thermal polymerization and distillation, so named because they are generally polymers of nine-carbon aromatic monomers. Usually the colors of thermal polymerized Hydrocarbon Resin C9 copolymerized resin are darker than cold-polymerization. Application: A. Paint Industries Paints mainly use Hydrocarbon Resin C9 petroleum resin with high softening points, Hydrocarbon Resin C9 petroleum resin can increase the gloss of paint and improve the adhesion and the hardness, anti-acid, alkaline- resistance, water-resistance. B. Adhesive Hydrocarbon Resin C9 petroleum resins have very good adhesiveness, they can increase the adhesion of adhesives especially for hot-melt adhesive, pressure-sensitive adhesive, coating, etc. C. Rubber and Tyre Mainly use Hydrocarbon Resin C9 petroleum resin with low softening point, these Hydrocarbon Resin C9 resin has very good mutual solubilities with natural rubber particles, non-affect to the sulphurization of rubber. D. Printing Ink Usually use Hydrocarbon Resin C9 petroleum resin with high softening point, they have color spreading, fast dry and brightening effects and will increase the printing properties. E. Other Hydrocarbon Resin C9 Petroleum resin has certain unsaturation property and can be used as paper glutting agents, plastic modifiers etc. Characters: Yellow color to brown color, Distinguished initial adhesion, Water-resistance, Low volatility, Low acid value, Good adhesion, Good viscosity, Good solubilities with vaious polymers, Specification: LESTAC-P Series Hydrocarbon Resin C9 Petroleum Resin LESTAC-P Series hydrocarbon resin is non-hazardous product, stored in dry and cool place with fire fighting facilities, far away from fire, sunshine, moisture and pollution. Related Products: Hydrocarbon Resin C9 Dark Color Hydrocarbon Resin C9 Wingtack 10 Hydrocarbon Resin C9 10 Light yellow liquid 1.5 0.90 370 -31 US, EU, Asia Wingtack 95 Hydrocarbon Resin C9 98 Light yellow solid 1.7 0.94 1100 52 US, EU, Asia Wingtack 98 Hydrocarbon Resin C9 98 Light yellow solid 2.3 0.95 1000 48 US, EU, Asia Wingtack RWT-7850 Hydrocarbon Resin C9 102 Light yellow solid 2.4 0.95 1000 56 US, EU, Asia Wingtack Plus Hydrocarbon Resin C9 96 Light yellow solid 1.6 0.95 1000 50 US, EU, Asia Wingtack EXTRA Hydrocarbon Resin C9 97 Light yellow solid 1.4 0.96 1100 52 US, EU, Asia Wingtack ET Hydrocarbon Resin C9 95 Light yellow solid 2.0 0.96 1000 47 US, EU, Asia Wingtack STS Hydrocarbon Resin C9 94 Light yellow solid 3.0 0.97 1000 44 US, EU, Asia Wingtack 86 Hydrocarbon Resin C9 87 Light yellow solid 1.2 0.98 650 42 US, EU, Asia Norsolene A-90 Hydrocarbon Resin C9 97 Yellow solid 5.6 1.10 750 46 US, EU, Asia Norsolene A-100 Hydrocarbon Resin C9 104 Yellow solid 5.6 1.10 800 53 US, EU, Asia Norsolene A-110 Hydrocarbon Resin C9 108 Yellow solid 5.6 1.10 850 64 US, EU, Asia Norsolene S-85 Hydrocarbon Resin C9 87 Yellow solid 6.5 1.07 650 45 US, EU, Asia Norsolene S-95 Hydrocarbon Resin C9 97 Yellow solid 6.5 1.07 700 46 US, EU, Asia Norsolene S95e Hydrocarbon Resin C9 93 Yellow solid 6.0 1.07 600 40 US, EU, Asia Norsolene S-105 Hydrocarbon Resin C9 106 Yellow solid 6.5 1.07 750 55 US, EU, Asia Norsolene S105e Hydrocarbon Resin C9 104 Yellow solid 6.0 1.07 650 50 US, EU, Asia Norsolene S-115 Hydrocarbon Resin C9 115 Yellow solid 6.5 1.07 800 65 US, EU, Asia Norsolene S115e Hydrocarbon Resin C9 115 Yellow solid 6.0 1.07 750 60 US, EU, Asia Norsolene S-125 Hydrocarbon Resin C9 125 Yellow solid 6.5 1.07 850 71 US, EU, Asia Norsolene S125e Hydrocarbon Resin C9 125 Yellow solid 6.0 1.07 850 70 US, EU, Asia Norsolene S-135 Hydrocarbon Resin C9 133 Yellow solid 6.5 1.07 950 82 US, EU, Asia Norsolene S135e Hydrocarbon Resin C9 135 Yellow solid 6.0 1.07 900 80 US, EU, Asia Norsolene S-145 Hydrocarbon Resin C9 143 Yellow solid 6.5 1.07 1050 92 US, EU, Asia Norsolene S-155 Hydrocarbon Resin C9 152 Yellow solid 6.5 1.07 1100 104 US, EU, Asia Norsolene M1080 Hydrocarbon Resin C9 93 Yellow solid 6.0 1.10 600 40 US, EU, Asia Norsolene M1090 Hydrocarbon Resin C9 103 Yellow solid 5.5 1.10 650 50 US, EU, Asia Norsolene M1100 Hydrocarbon Resin C9 112 Yellow solid 5.5 1.10 750 60 US, EU, Asia Norsolene W-85 Hydrocarbon Resin C9 85 Colorless solid <1 1.06 600 35 US, EU, Asia Norsolene W-90 Hydrocarbon Resin C9 90 Colorless solid <1 1.06 650 40 US, EU, Asia Norsolene W-100 Hydrocarbon Resin C9 100 Colorless solid <1 1.06 750 50 US, EU, Asia Norsolene W-110 Hydrocarbon Resin C9 110 Colorless solid <1 1.06 850 60 US, EU, Asia Norsolene W-120 Hydrocarbon Resin C9 120 Colorless solid <1 1.06 950 70 US, EU, Asia Norsolene W-130 Hydrocarbon Resin C9 130 Colorless solid <1 1.06 1100 80 US, EU, Asia Norsolene W-140 Hydrocarbon Resin C9 140 Colorless solid <1 1.06 1200 90 US, EU, Asia Hydrocarbon Resin C9, Aromatic Resins As discussed in the section on Hydrocarbon Resin C9, Aliphatic Resins, the feedstocks for hydrocarbon resins are produced via cracking of naphtha. Basic Hydrocarbon Resin C9, aromatic resins are produced from Hydrocarbon Resin C9 resin oil that contains various monomers as illustrated in Figure 1. Figure 1: Hydrocarbon Resin C9 Resin Oil Composition Hydrocarbon Resin C9 Resin Oil Composition A cationic polymerization reaction converts the liquid feed to a hard resin as seen in Figure 2. Figure 2: Hydrocarbon Resin C9 Resin Oil Polymerization Hydrocarbon Resin C9 Resin Oil Polymerization The aromatic characteristics of the feedstocks are preserved in the final resin polymer so the molecular weight and solubility properties of Hydrocarbon Resin C9 resins are considerably different from those of Hydrocarbon Resin C9, aliphatic tackifiers. Since Hydrocarbon Resin C9 resin oil is a relatively unrefined material, its polymerization leads to much darker resins than other hydrocarbon resins. Due to their aromatic structure, Hydrocarbon Resin C9 resins are more compatible with polar elastomers than Hydrocarbon Resin C9 resins. They are most commonly used in systems based on styrene butadiene rubber, styrene-butadiene-styrene block copolymers, polychloroprene rubber, ethylene vinyl acetate copolymers with high levels of vinyl acetate (>28%), chlorinated paraffins, paints, and concrete curing compounds. Table 1: Property Ranges of Hydrocarbon Resin C9, Aromatic Hydrocarbon Resins Properties Range Ring and ball softening point, °C 100–142 Gardner color (50% in toluene) 6–12 Glass transition temperature, °C 40–85 MMAP cloud point, °C 2–45 DACP cloud point, °C 35–100 HYDROCARBON RESINS (Hydrocarbon Resin C9 AND Hydrocarbon Resin C9 RESINS) PROPERTIES Hydrocarbon resins are amorphous thermoplastic polymers produced by polymerization of unsaturated hydrocarbons. The feedstock are various by-products of naphtha crackers.1 These resins have typically a low molecular weight ranging from about 400 to 5000 g/mol. The three main types are Hydrocarbon Resin C9 aliphatic, Hydrocarbon Resin C9 aromatic, and DCPD cycloaliphatic resins. They are sometimes hydrogenated to reduce discoloration and to improve their heat and UV stability. Aliphatic hydrocarbon resins (Hydrocarbon Resin C9 Resins) are made from Hydrocarbon Resin C9 piperylene and its derivatives. The most important ones are cis/trans 1,3-pentadienes, 2-methyl-2-butene, cyclopentene, cyclopentadiene, and dicyclopentadiene (see below). These monomers are polymerized to oligomeric resins with low to high softening point using Lewis acid catalysts. Hydrocarbon Resin C9 resins are aliphatic in nature and are, therefore, fully compatible with natural rubber, most olefins (LDPE) and many synthetic elastomers of low polarity. They are available in a wide range of molecular weights (MW) and softening points (solid grades 85 - 115°C and liquid grades 5 - 10°C) and provide outstanding tack. They also have a light yellow to light brown color and possess excellent heat stability. Hydrocarbon Resin C9 Aromatic hydrocarbon resins (Hydrocarbon Resin C9 Resins) are made from Hydrocarbon Resin C9 aromatic hydrocarbons. Their composition depends on the hydrocarbon feedstock (coal tar, crude oil). The most important base monomers are indene, methyindenes, dicyclopentadiene, styrene, alpha-methylstyrene and various vinyl toluenes (see below). These resins are available in a wide range of softening points. Compared to Hydrocarbon Resin C9 resins, they have a much higher melt viscosity, are of darker color (dark yellow to brown)2 and have higher softening point ranging from about 100 to 150°C.3 Hydrocarbon Resin C9 resins are very versatile resins that are compatible with many polymers. Hydrocarbon Resin C9 Resin Hydrogenated Hydrocarbon Resin C9/ Hydrocarbon Resin C9 resins and resin blends are also commercially available. These resins are often colorless and have improved heat and color stability. However, they are also noticeably more expensive and thus, only used if superior heat and color stability is of concern. COMMERCIAL HYDROCARBON RESINS Hydrocarbon resins are commercially available in large quantities. Major manufacturers and suppliers of these resins are APPLICATIONS Hydrocarbon resins are used as tackifiers, performance modifiers and homogenizing agents. They are extensively used in the manufacture of rubbers, coatings, printing inks, and adhesives. The largest market for hydrocarbon resins are hot melts, PSA tapes and labels. They are important ingredients in many rubber adhesive formulations, particularly synthetic rubbers that are less tacky than natural rubber. They improve tack, peel strength, and increase the glass transition temperature, which in turn improves shear strength. In paints, they provide superior pigment wetting, enhanced adhesion, gloss, and film hardness. They also improve flow and leveling, reduce VOCs and provide improved mildew and water resistance. 1Naphtha is an oily liquid produced by fractional distillation of crude oil (petroleum). It is the fraction between gasoline and kerosene that is usually further refined in a so-called naphtha cracker. Other feedstocks for naphtha include coal tar, natural gas and other carbon-rich compounds. 2Highly purified water-white grades are also commercially available which have improved color stability. Hydrocarbon resin is a Hydrocarbon Resin C9/ Hydrocarbon Resin C9 aromatic hydrocarbon used in industrial applications. It has a tackifying effect and is suitable for use in paint, printing ink, adhesives, rubber and other areas where tackiness is required.[1] It is a kind of thermal plasticizing hydrocarbon resin produced by Hydrocarbon Resin C9, Hydrocarbon Resin C9 fraction, by-products of petroleum cracking, through pretreatment, polymerization and distillation. It is not a high polymer but a low polymer with the molecular weight between 300-3000. Featured by acid value, easy mutual solubilities, resistant to water, resistant to ethanol and chemicals. It has the chemical stabilizing property to acid and alkaline, viscosity adjusting and thermal stabilizing, Generally, the petroleum resins are not used independently, but have to be used together with other kinds of resins as promoters, adjusting agents and modifiers in hot-melt adhesive, pressure-sensitive adhesive, hot melt road marking paint,[2] rubber tires and so on. There are various types of hydrocarbon resins include Hydrocarbon Resin C9 Resins, Hydrocarbon Resin C9 Resins, Hydrocarbon Resin C9/ Hydrocarbon Resin C9 copolymer resins, and hydrogenated resins. Hydrocarbon Resin C9 Resins are produced from aliphatic crackers like Piperylene and Isoprene, the current major catalyst is AlCl3. Hydrocarbon Resin C9 Resins are produced from aromatic crackers like Vinyltoluenes, Indene, Alpha Methylstyrene, Stryene, Methylindenes, etc, the current major catalyst is BF3. Hydrocarbon Resin C9/ Hydrocarbon Resin C9 copolymer resins are produced from both aliphatic crackers and aromatic crackers. Regarding to hydrogenated resins, there are some additional process like hydrogenated (use hydrogen), by this way, the double bond is neutralized and light color even water white resins are produced. There are some different types, including hydrogenated Hydrocarbon Resin C9 Resins, hydrogenated Hydrocarbon Resin C9 Resins, Hydrogenated Hydrocarbon Resin C9/ Hydrocarbon Resin C9 Resin, and Hydrogenated DCPD resins. [3] Hydrocarbon Resin C9 Petroleum Resin Hydrocarbon Resin C9 aromatic petroleum resin, hydrocarbon resin could be widely used in solvent based adhesives, hot melt adhesives, alkyd based paints, rubber and printing inks. * Hydrocarbon Resin C9 Thermal-Polymerization Hydrocarbon Resin * Hydrocarbon Resin C9 Catalytic-Polymerization Hydrocarbon Resin Hydrocarbon Resin C9 Thermal-Polymerization Hydrocarbon Resin Hydrocarbon Resin C9 thermal-polymerization hydrocarbon resin is widely used in anti-corrosive coating, alkyd-based enamel, aluminium paint, varnish, marine paint, offset ink, newspaper ink and rubber compounding. Item UCH-100 UCH-120 UCH-130 UCH-140 Colour, Gardner (max) 9-10 9-11 10-12 11-12 Softening Point (R&B) ℃ 91-100 116-125 126-135 135-140 Bromine Value (Br cg/g) 85 max 85 max 85 max 85 max Acid Number (KOHmg/g) 0.1 max 0.1 max 0.1 max 0.1 max Hydrocarbon Resin C9 Catalytic-Polymerization Hydrocarbon Resin Hydrocarbon Resin C9 pale yellow catalytic-polymerization aromatic hydrocarbon resins have good compatibility with EVA, SBS ect, which are suitable for solvent based adhesives and hot melt adhesives. Also can used in paing and coating. G-Modified Petroleum Resin (Hydrocarbon Resin C9/ Hydrocarbon Resin C9) Product Introduction: QILONG® G-Series Hydrocarbon resin is aliphatic modified aromatic resin obtained from copolymerizing of Hydrocarbon Resin C9 and Hydrocarbon Resin C9 fraction that derived from the by-product of thermal cracking of naphtha. It is granular solid with the color of pale yellow. Its' major usage is binder for hot melt road marking and tackifier for hot melt adhesives, rubber compound. This resin shows outstanding affinity for pigments, superior process ability in the hot melt road marking application and good compatibility with base polymer, natural tackifier and good heat stability in hot melt adhesive application. Hydrocarbon Resin C9 RESINS Hydrocarbon Resin C9 The products are yellow brittle thermoplastic solid. And the products are characteristic of good transparency, gloss, solubility, waterproof, insulation and chemical stability, adhesion and high resistance to acid and alkali. They can best mixed with oil, alkyd resin, and chloroethylene. And they can easily dissolve in ester and aromatic hydrocarbon solvent and partly or completely dissolve in ketone and fatty hydrocarbon. The resins Hydrocarbon Resin C9 are used in painting, oil painting, rubber and adhesive industries. Hydrocarbon Resin C9 / Hydrocarbon Resin C9 RESINS Hydrocarbon Resin C9/ Hydrocarbon Resin C9 Copolymerized Resins Hydrocarbon Resin C9/ Hydrocarbon Resin C9 copolymerized petroleum resins are obtained by pretreatment, polymerization, distillation of Hydrocarbon Resin C9 and Hydrocarbon Resin C9 streams from steam crackers. Uses: Aromatic Petroleum Resin are used for producing paints, rubbers, adhesives, printing inks.When added to paints, can improve the finish, adhesiveness and hardness of paint films. HYDROGENATED Hydrocarbon Resin C9 resins Obtained from hydrogenation of Hydrocarbon Resin C9 stream polymerized resins, low color Use in adhesives. Hydrogenated Hydrocarbon Resin C9 resins Obtained from hydrogenation of Hydrocarbon Resin C9 stream polymerized resins, very low color odorless granules. Used in variety of applications requiring low color very stable resin: coatings, adhesives, plastic modification. Hydrocarbon Resin C9 RESINS Hydrocarbon Resin C9 Petroleum Resins for Road Marking For hot melt road painting, which can enhance the tenacity, hardness and adhesive force of paint material and form a smooth coating surface. Hydrocarbon Resin C9 Petroleum Resins for Adhesives For producing hot melt adhesives, pressure sensitive adhesives and in synthetic rubbers formulations. Homogenisator 501, Deotack 920 / 930 / 940 are aromatic Hydrocarbon Resin C9 hydrocarbon resins. Hydrocarbon Resin C9 hydrocarbon resins are versatile in use and widely compatible with various polymers. Major application areas are hot melts, printing inks, paints and solvent based adhesives. Due to their aromatic structure, Hydrocarbon Resin C9 hydrocarbon resins are more compatible with polar elastomers than a Hydrocarbon Resin C9 resin. Deotack 1100 is a slightly yellowish, aliphatic Hydrocarbon Resin C9-hydrocarbon resin. Deotack 1100 is primarily utilized for adhesive tape coatings, contact adhesives, hot glues, as well as for roadway markings. Hydrocarbon Resin C9 resins provide a good balance between adhesion strength and cohesion. Hydrocarbon Resin C9 Aromatic Hydrocarbon Resin Benefits: BP series is specially designed for adhesives application. Characterised by lighter colour, less odour as well as wider compatibility and solubility, they are more suitable for hot melt adhesives, bookbinding, shoes adhesive and solvent adhesives etc. Applications: The major applications areas are paints and varnishes, printing inks, adhesives, rubber and elastomers etc. Products Bitoner Hydrocarbon Resin C9 Resin BP-100 Bitoner Hydrocarbon Resin C9 BP-100 is an odour improved aromatic hydrocarbon resin in low softening point of 95-105℃. With light colour and less odour, good compatibility with EVA, SBS and other polymers. Find out more Bitoner Hydrocarbon Resin C9 Resin BP-120 Bitoner Hydrocarbon Resin C9 BP-120 is an odour improved light colour aromatic hydrocarbon resin with softening point of 115-125°C. It performs very low VOC, low naphthalene content and wide compatibility with EVA, SBS and other polymers. Find out more Bitoner Hydrocarbon Resin C9 Resin BP-140 Bitoner Hydrocarbon Resin C9 BP-140 is an odour improved petroleum resin with softening point 130-140°C. Find out more Bitoner Resin Ba-100 Bitoner Hydrocarbon Resin C9 Resin BA-100 is a light colour, low VOC, Hydrocarbon Resin C9 Resin with good compatibility with EVA, popular for EVA-based paper converting hot melt adhesives. Bitoner BA-100 is a slightly yellow granular aromatic resin obtained from petroleum-derived monomers. It is an odour improved grade with extremely low odour, good compatibility with other resins and polymers. Find out more Bitoner Resin Ba-110 BA-110 is odour improved Hydrocarbon Resin C9 resin, with low VOC, good compatibility with EVA, SBS, CR, etc. Bitoner BA-110 is a slightly yellow granular aromatic resin obtained from petroleum-derived monomers. It is an odour improved grade with extremely low odour, good compatibility with other resins and polymers. Find out more Bitoner Resin Ba-120 BA-120 is an odour-improved Hydrocarbon Resin C9 resin, with low VOC, good compatibility with EVA, SBS, CR, etc. Bitoner Ba-120 is slightly yellow granular aromatic resin obtained from petroleum-derived monomers. It is an odour improved grade with extremely low odour, good compatibility with other resins and polymers. Find out more Bitoner Resin Hydrocarbon Resin C9 BP-150 Bitoner Hydrocarbon Resin C9 BP-150 is an odour improved aromatic hydrocarbon resin with high softening point of 140-150℃. Find out more CN Hydrocarbon Resin C9 DCPD RESIN, made from Dicyclopentadiene, is also a new thermal plasticizing resin. With a unique combination of light color and moderate softening point. It is characterized by lower hydrogen content; typical filler characteristics excellent adhesive properties. With lower softening points, the resin has very good mutual solubility with natural rubber particles, No affect to the sulphurization of rubber. DESCRIPTION Color:13-18# Softening point:90-130℃ Hydrocarbon Resin C9 has the characteristics of low acid value, good miscibility, chemical stability against acid and alkali, good adjustment of viscosity and thermal stability. Hydrocarbon resin C9 is generally not used alone, but as promoters, adjusting agents, modifiers and other resins used together. Application area: 1.Paint: Hydrocarbon resin C9 can increase the added paint gloss paint, paint film adhesion, hardness, acid and alkali resistance. 2.Rubbe,tyre industry: Rubber and Tyre are mainly use the low softening point of hydrocarbon resin C9. Such resins and natural rubber particles have a good miscibility of the rubber vulcanization process is not a big impact, add oil and rubber tires can play a tackifying resin, reinforcement, softening effect. 3.The ink industry: petroleum resin, ink, mainly high softening point petroleum resin. Add oil and resin ink color development can play, quick-drying and brightening effects and improve printing performance and so on. 4.Asphalt modifier: Mainly with high softening point of Hydrocarbon Resin C9 petroleum resin, increase the viscosity of bitumen to improve asphalt performance. CFN C5/C9 Copolymerized Petroleum Resin C5/C9 Copolymerized Petroleum Resin is a thermoplastic resin, Hydrocarbon Resin C9, Hydrocarbon Resin C9 fraction of petroleum by-product of decomposition with processing pre-treatment, polymerization and distillation. It is not a high polymer, but low polymer with the molecular weight range of 300-3000. Hydrocarbon Resin C9/ Hydrocarbon Resin C9 has advantages both of Hydrocarbon Resin C9 and Hydrocarbon Resin C9 petroleum resin: low acid value, good miscibility, waterproof, ethanol resistance and chemical resistance and other characteristics of acid resistance, chemical stability in acid-bases, adjustment in viscosity, good thermal stability, weather resistance and light aging resistance because of non-polar groups in its structure. Hydrocarbon Resin C9/ Hydrocarbon Resin C9 has good solubility in organic solvents especially in oil solvent, as well as good compatibility with other resins. It also has brittle, increasing viscosity, cohesiveness and plasticity. Generally, it is not used alone, but used as accelerant , regulator and modifier together with other resins. Application area: The products are used in hot melt adhesives, pressure sensitive adhesives, sealants, adhesives and other civil and rubber and tire field of adhesives used as tackifying resin; for rubber, tire, radial tire especially high requirements of rubber products. CND Hydrocarbon Resin C9 Dark Color Hydrocarbon Resin Hydrocarbon Resin C9 dark color hydrocarbon resin is yellow granular solid thermoplastic resin, it is manufactured by ethylene Hydrocarbon Resin C9 fractions, with a special production process, generated by the polymerization and the molecular weight range 300-3000 low molecular weight polymer. Hydrocarbon resin C9 has the characteristics of low acid value, good miscibility, chemical stability against acid and alkali, good adjustment of viscosity and thermal stability. Hydrocarbon resin C9 is generally not used alone, but as promoters, adjusting agents, modifiers and other resins used together. Application area: 1.Paint: Hydrocarbon resin C9 can increase the added paint gloss paint, paint film adhesion, hardness, acid and alkali resistance. 2.Rubbe,tyre industry: Rubber and Tyre are mainly use the low softening point of hydrocarbon resin C9. Such resins and natural rubber particles have a good miscibility of the rubber vulcanization process is not a big impact, add oil and rubber tires can play a tackifying resin, reinforcement, softening effect. 3.Adhesive industry: Hydrocarbon resin C9 has good adhesion, the adhesive and pressure-sensitive adhesive resin with added materials can improve the adhesive bond strength, acid resistance, alkali resistance and water resistance, and can effectively reduce production costs. 4.The ink industry: petroleum resin, ink, mainly high softening point petroleum resin. Add oil and resin ink color development can play, quick-drying and brightening effects and improve printing performance and so on. 5.other: Resin has certain Unsaturation, can be used to glue on paper CNL Light Color Hydrocarbon Resin C9 Light color Hydrocarbon resin C9 is light yellow granular solid thermoplastic resin, it is manufactured by ethylene Hydrocarbon resin C9 fractions, with a special production process, generated by the polymerization and the molecular weight range 300-3000 low molecular weight polymer. Hydrocarbon resin C9 Light color Hydrocarbon resin has the characteristics of low acid value, good miscibility, chemical stability against acid and alkali, good adjustment of viscosity and thermal stability. Hydrocarbon resin C9 is generally not used alone, but as promoters, adjusting agents, modifiers and other resins used together. Application area: 1.Paint: Light color Hydrocarbon resin C9 can increase the added paint gloss paint, paint film adhesion, hardness, acid and alkali resistance. 2.Rubbe,tyre industry: Rubber and Tyre are mainly use the low softening point of Light color hydrocarbon resin C9. Such resins and natural rubber particles have a good miscibility of the rubber vulcanization process is not a big impact, add oil and rubber tires can play a tackifying resin, reinforcement, softening effect. 3.Adhesive industry: Hydrocarbon resin C9 has good adhesion, the adhesive and pressure-sensitive adhesive resin with added materials can improve the adhesive bond strength, acid resistance, alkali resistance and water resistance, and can effectively reduce production costs. 4.The ink industry: petroleum resin, ink, mainly high softening point petroleum resin. Add oil and resin ink color development can play, quick-drying and brightening effects and improve printing performance and so on. 5.other: Resin has certain Unsaturation, can be used to glue on paper. ed materials can improve the adhesive bond strength, acid resistance, alkali resistance and water resistance, and can effectively reduce production costs. 4.The ink industry: petroleum resin, ink, mainly high softening point petroleum resin. Add oil and resin ink color development can play, quick-drying and brightening effects and improve printing performance and so on. 5.other: Resin has certain Unsaturation, can be used to glue on paper.
HYDROCHLORIDE 20%
Hydrochloride 20% shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Hydrochloride 20% is available also as a solid.
Hydrochloride 20%s play a crucial role in pharmaceuticals due to their ability to enhance the solubility, stability, and bioavailability of active pharmaceutical ingredients.

CAS Number: 7647-01-0
Molecular Formula: ClH
Molecular Weight: 36.46
EINECS Number: 231-595-7

hydrochloric acid, hydrochloric acid, 7647-01-0, Muriatic acid, chlorane, Chlorohydric acid, Acide chlorhydrique, Anhydrous hydrochloric acid, Chlorwasserstoff, Muriaticum acidum, Chloorwaterstof, Chlorowodor, Acido cloridrico, Bowl Cleaner, Hydrogen chloride (HCl), chlorure d'hydrogene, Hydrogenchlorid, 4-D Bowl Sanitizer, Emulsion Bowl Cleaner, Caswell No. 486, Baume hcl, Icon etch, Acido clorhidrico, Aqueous hydrogen chloride, Hydrochloric acid [JAN], UN 1050 (anhydrous), Enplate po 236, White Emulsion Bowl Cleaner, Chloruro de hidrogeno, Hydrochloric acid gas, NSC 77365, HSDB 545, chloridohydrogen, Hygeia Creme Magic Bowl Cleaner, CHEBI:17883, Marine acid, monohydrochloride, Percleen Bowl and Urinal Cleaner, Wasserstoffchlorid, Chlorure d'hydrogene anhydre, Cloruro de hidrogeno anhidro, EINECS 231-595-7, Hydrochloric acid, anhydrous, UNII-QTT17582CB, NSC-77365, cloruro de hidrogeno, Acidum hydrochloricum, EPA Pesticide Chemical Code 045901, INS NO.507, QTT17582CB, HCl, INS-507, Hydrogen chloride (acid), [HCl], Varley's Ocean Blue Scented Toilet Bowl Cleaner, Hydrogen chloride, anhydrous, DTXSID2020711, E-507, EC 231-595-7, MFCD00011324, Hydrogen chloride, refrigerated liquid, E507, (HCl), HYDROCHLORIC ACID (II), HYDROCHLORIC ACID [II], Chlorowodor [Polish], HYDROCHLORIC ACID (IARC), HYDROCHLORIC ACID [IARC], HYDROCHLORIC ACID (MART.), HYDROCHLORIC ACID [MART.], Chloorwaterstof [Dutch], Chlorwasserstoff [German], Hydrogen Chloride - Methanol Reagent, Acid, Muriatic, Hydrochloric acid, ACS reagent, 37%, mono hydrochloride, Acido cloridrico [Italian], Acido clorhidrico [Spanish], Acide chlorhydrique [French], Hydrogen chloride (gas only), Chlorure d'hydrogene [French], Chloruro de hidrogeno [Spanish], UN1050, UN1789, UN2186, Anhydrous hydrogen chloride, Chlorure d'hydrogene anhydre [French], Cloruro de hidrogeno anhidro [Spanish], UN 2186 (refrigerated liquefied gas), chlorum, hydochloride, hydrochlorie, hydrochoride, hydrocloride, Salzsaeure, Hydrochloric acid [JAN:NF], hydro chloride, hydro-chloride, hydrogenchloride, Soldering acid, chlorhydric acid, hydochloric acid, hydogen chloride, hydrochoric acid, hydrocloric acid, hydrogen chlorid, hydrogen choride, hydrogen cloride, hyrochloric acid, hyrogen chloride, Liriopesides-B, AescinIIB, hvdrochloric acid, hvdrogen chloride, hydorchloric acid, hydrochioric acid, hydrochloric aicd, hydrochloric-acid, hydrogen-chloride, hyrdochloric acid, Hydrochloric ccid, Acidum Muriaticum, monohydro-chloride, Sibiricose-A6, hydrogen ch1oride, hydro chloric acid, hydro-chloric acid, hydrochloric ac id, Hydrogen chloride, 4M in dioxane, hydro- chloric acid, HEMMORHOIDS, Caswell No 486, trans-stilben-2-ylamine; hydrochloride, H-Cl, Hydrochloric Acid Blank, Hydrochloric acid 37%, Dilute hydrochloric acid, Diluted hydrochloric acid, HCL], Hydrochloric acid, 37%, Hydrogen chloric anhydrous, Hydrochloric acid, diluted, Hydrochloric acid 36% by weight or more HCl, 17Cl, Hydrogen-chloride-anhydrous-, Acidum hydrochloricum dilutum, DTXCID20711, HYDROCHLORIC ACID [MI], HYDROGEN CHLORIDE [MI], Hydrochloric acid (JP15/NF), HYDROCHLORIC ACID [FCC], CHEMBL1231821, Hydrochloric acid (JP17/USP), HYDROCHLORIC ACID [HSDB], HYDROCHLORIC ACID [INCI], MURIATICUM ACIDUM [HPUS], HYDROCHLORIC ACID, TRIMER, HYDROCHLORIC ACID [VANDF], Hydrochloric acid ACS grade 31%, HYDROCHLORIC ACID [WHO-DD], HYDROCHLORIC ACID [WHO-IP], Hydrochloric acid, AR, 35-37%, Hydrochloric acid, LR, 35-38%, NSC77365, Hydrochloric acid, 3 M in methanol, Hydrogen Chloride - Butanol Reagent, BDBM50499188, CCG-221928, DB13366, Hydrochloric acid, p.a., 31-33%, Hydrogen chloride, 1M in acetic acid, AKOS015843726, CCJ-221928, DB13366, Hydrochloric acid, puriss., 30-33%, Hydrochloric acid, reagent grade, 37%, Hydrogen chloride, 1M in diethyl ether, Hydrogen chloride, 2M in diethyl ether, NA 1789, UN 1050, UN 1789, UN 2186, Hydrogen chloride, puriss., >=99.7%, Hydrogen chloride, puriss., >=99.8%, Hydrochloric acid ACS grade 36.5-38%, Hydrochloric acid, technical grade, 30%, 1082661-04-8, Hydrochloric acid (acid aerosols including mists, vapors, gas, fog, and other airborne forms of any particle size), 1N Hydrochloric Acid aqueous (+/-0.1N), 3N Hydrochloric Acid aqueous (+/-0.2N), 5N Hydrochloric Acid aqueous (+/-0.2N), Hydrochloric acid, puriss. p.a., >=32%, ACIDUM HYDROCHLORICUM [WHO-IP LATIN], H1060, H1062, H

In pharmaceutical contexts, Hydrochloride 20% might refer to a medication formulation where the active ingredient is present in the form of a hydrochloride salt at a concentration of 20%.
Hydrochloride 20%, polyhexanide or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
The presence of multiple hydrogen bond and chelation sites within PHMB renders it of potential interest in the field of supramolecular chemistry.

When a drug is formulated as a Hydrochloride 20%, it often exhibits improved characteristics such as increased water solubility, which can lead to faster dissolution and absorption in the body.
This is particularly advantageous for drugs that have poor solubility in their free base form.
Hydrochloride 20% occurs as a clear, colorless, fuming aqueous solution of hydrogen chloride, with a pungent odor.

Hydrochloride 20%, also known as muriatic acid or spirits of salt, is an aqueous solution of hydrogen chloride (HCl).
Hydrochloride 20% is a colorless solution with a distinctive pungent smell.
Hydrochloride 20% is classified as a strong acid.

Hydrochloride 20% is a component of the gastric acid in the digestive systems of most animal species, including humans.
Hydrochloride 20% is an important laboratory reagent and industrial chemical.
Because it was produced from rock salt according to the methods of Johann Rudolph Glauber, hydrochloric acid was historically called by European alchemists spirits of salt or acidum salis (salt acid).

Hydrochloride 20% was called marine acid air.
The name muriatic acid has the same origin (muriatic means "pertaining to brine or salt", hence muriate means hydrochloride), and this name is still sometimes used.
Hydrochloride 20% a water solution of hydrogen chloride of varied concentrations.

Hydrochloride 20% is a clear, colorless or slightly yellowish, corrosive liquid having a pungent odor.
Hydrochloride 20% is miscible with water and with alcohol. Concentrations of hydrochloric acid are expressed in percent by weight, or may be expressed in Baume degrees (Be0) from which percentages of hydrochloric acid and specific gravities may readily be derived.
The usually available concentrations are 18°, 20°, 22°, and 23° Be.

Concentrations above 13° Be (19.6%) fume in moist air, lose hydrogen chloride, and create a corrosive atmosphere.
Because of these characteristics, suitable precautions must be observed during sampling and analysis to prevent losses.
Hydrochloride 20% is produced by various methods that might impart trace amounts of organic compounds as impurities.

The manufacturer, vendor, or user is responsible for identifying the specific organic compounds that are present and for meeting the requirements for organic compounds.
Methods are provided for their determination.
In applying the procedures any necessary standards should be used to quantitate the organic compounds present in each specific product.

Hydrochloride 20%, or hydrogen chloride, is either a colorless liquid with a pungent odor, or a colorless to slightly yellow gas that can be shipped as a liquefi ed compressed gas.
The acid is used in the production of fertilizers, dyes, dyestuffs, artifi cial silk, and paint pig- ments, and in refi ning edible oils and fats.
Hydrochloride 20% is also used in electroplating, leather tanning, ore refi ning, soap refi ning, petroleum extraction, and pickling of metals, and is used in the photographic, textile, and rubber industries.

In addition, Hydrochloride 20% is used as an antiseptic in toilet bowls against animal pathogenic bacteria, and in food processing as a starch modifi er.
Hydrochloride 20%, is a colorless, fuming, highly toxic gas that is soluble in water, alcohol, and ether.
Hydrochloride 20% is used in polymerization, isomerization, and the synthesis of vinyl chloride and alkyl chloride.

Hydrochloride 20% is a colorless to yellowish liquid (the yellow colorationmay be due to traces of iron, chlorine or organics contaminants); fumes in air;refractive index of 1.0 N solution 1.3417; density of commercial concentratedacid (37.8 g/100g solution) 1.19 g/mL, and constant boiling solution (20.22g/100g solution) 1.096 g/mL at 25°C; forms a constant boiling azeotrope withwater at HCl concentration 20.22%; the azeotrope boils at 108.6°C; severalmetal chlorides can be salted out of their aqueous solutions by addition ofHCl; the addition of CaCl2can break the azeotrope; the pH of the acid at 1.0,0.1 and 0.01 N concentrations are 0.10, 1.1, and 2.02, respectively; a 10.0 Msolution ionizes to 92.6% at 18°C.

The compound hydrogen chloride has the chemical formula HCl and as such is a hydrogen halide.
At room temperature, it is a colorless gas, which forms white fumes of hydrochloric acid upon contact with atmospheric water vapor.
Hydrogen chloride gas and hydrochloric acid are important in technology and industry.

Hydrochloride 20%, the aqueous solution of hydrogen chloride, is also commonly given the formula HCl.
Hydrochloride 20% is a diatomic molecule, consisting of a hydrogen atom H and a chlorine atom Cl connected by a polar covalent bond.
The chlorine atom is much more electronegative than the hydrogen atom, which makes this bond polar.

Consequently, the molecule has a large dipole moment with a negative partial charge (δ−) at the chlorine atom and a positive partial charge (δ+) at the hydrogen atom.
In part because of its high polarity, Hydrochloride 20% is very soluble in water (and in other polar solvents).
The bactericidal ability of Hydrochloride 20% solution is better than other bactericides.
In particular, the product's unique long-term antibacterial effect and the ability to prevent secondary infection are not achieved by other fungicides.

Hydrochloride 20%s are commonly used in pharmaceuticals to improve the solubility, stability, and bioavailability of drugs.
Many drugs exist in basic form, and converting them into their hydrochloride salt form can enhance their pharmacokinetic properties, making them more suitable for medicinal use.
Hydrochloride 20% serve as important reagents and catalysts in chemical synthesis processes.

They can facilitate various organic reactions and are utilized in the production of numerous chemical compounds.
Hydrochloride 20% is used in analytical chemistry as reference standards and calibration solutions.
They help in the accurate quantification and analysis of substances in laboratory settings.

In industrial applications, hydrochloride salts find utility in diverse processes, including water treatment, metal refining, and manufacturing of various chemical products.
Hydrochloride 20% is valuable compounds in research laboratories for investigating the properties and behavior of different chemical substances.
They are often used in experimental setups and studies across multiple scientific disciplines.

Hydrochloride salts are preferred in drug formulation due to their higher stability compared to other salt forms.
They can provide better shelf life and ensure consistent dosing in pharmaceutical products.
In pharmaceuticals, Hydrochloride 20% is sometimes used to mask the bitter taste of certain drugs, thereby improving patient compliance and acceptability of medications, especially in pediatric and geriatric populations.

Hydrochloride 20% is generally compatible with a wide range of excipients and other components used in pharmaceutical formulations, making them versatile in drug development and manufacturing.
Hydrochloride 20% is considered safe for pharmaceutical use when formulated appropriately and administered according to prescribed guidelines.
They undergo rigorous testing to ensure purity, quality, and compliance with regulatory standards.

Some Hydrochloride 20%s have specialized applications beyond pharmaceuticals and chemicals.
For example, they may be used in food additives, veterinary medicine, or in specific industrial processes where their properties are advantageous.
The use of Hydrochloride 20% in pharmaceuticals is subject to regulatory oversight by health authorities in different countries.

Manufacturers must comply with regulatory requirements regarding product quality, safety, and efficacy.
Ongoing research in the field of drug delivery and formulation continues to explore innovative ways to utilize Hydrochloride 20% for improved drug delivery systems, controlled release formulations, and targeted therapies.

Melting point: -35 °C
Boiling point: >100 °C (lit.)
Density: 1.2 g/mL at 25 °C (lit.)
vapor density: 1.3 (vs air)
vapor pressure: 613 psi ( 21.1 °C)
refractive index: 1.3535
Flash point: 10℃ (tag closed test)
storage temp.: Store at +2°C to +25°C.
solubility: H2O: soluble
form: liquid
pka: -7(at 25℃)
color: Light Yellow
Specific Gravity: 1.19
Odor: Sharp, irritating odor detectable at 0.25 to 10 ppm
PH: 3.01(1 mM solution);2.04(10 mM solution);1.08(100 mM solution);
Viscosity: 1.7mm2/s
Water Solubility: miscible
Sensitive: Air & Light Sensitive
Merck: 14,4780
Dielectric constant: 4.6(20℃)
Exposure limits Ceiling limit 5 ppm (~ 7 mg/m3).

Hydrochloride 20% can be incorporated into various dosage forms, including tablets, capsules, solutions, suspensions, and injectables.
This flexibility allows for tailored formulations based on the specific needs of patients and the desired route of administration.
In addition to their role as active pharmaceutical ingredients (APIs), hydrochloride salts can also be used to adjust the pH of formulations.

This is particularly important in pharmaceuticals where pH levels can impact stability, solubility, and overall efficacy.
Hydrochloride 20% often exhibit different crystalline forms, each with its own physical and chemical properties.
Understanding and controlling these crystalline forms is crucial for optimizing drug formulation and ensuring consistent product performance.

Some hydrochloride salts may be hygroscopic, meaning they have a tendency to absorb moisture from the surrounding environment.
This characteristic can influence formulation stability and storage conditions, requiring careful consideration during product development.
Analyzing hydrochloride salts in pharmaceutical formulations requires robust analytical methods to accurately quantify the salt content, assess purity, and monitor stability over time.

Techniques such as chromatography, spectroscopy, and titration are commonly employed for this purpose.
Specifications for hydrochloride salts, including testing methods and acceptance criteria, are often outlined in pharmacopeial monographs such as the United States Pharmacopeia (USP), European Pharmacopoeia (Ph. Eur.), and others.
Compliance with these standards ensures product quality and consistency.

Pharmaceutical formulations involving Hydrochloride 20% may be protected by patents, especially if they involve novel compositions, formulations, or methods of use.
Intellectual property considerations play a significant role in drug development and commercialization strategies.
Hydrochloride 20% are produced and supplied by various manufacturers worldwide.

Ensuring a reliable and secure supply chain is essential for pharmaceutical companies to meet market demand and maintain uninterrupted availability of medications.
Basilus Valentinus of Italy was first to isolate the acid and reported it under the name spiritus salis in the fifteenth century.
Glauber prepared this acid by the reaction of sulfuric acid with common salt in 1648.

Lavoisier proposed the name muriatic acid in 1789 after muriate, the term referring to a chlorine-containing inorganic substance.
Sir Humphrey Davy proved the gas was composed of only hydrogen and chlorine in 1810.
Subsequently, the gas was named hydrogen chloride.

Dilute Hydrochloride 20% occurs in the stomachs of mammals. Gaseous hydrogen chloride occurs in trace concentrations in the atmosphere
During the Industrial Revolution in Europe, demand for alkaline substances increased.
A new industrial process developed by Nicolas Leblanc of Issoudun, France enabled cheap large-scale production of sodium carbonate (soda ash).

In this Leblanc process, common salt is converted to soda ash, using sulfuric acid, limestone, and coal, releasing hydrogen chloride as a by-product.
Until the British Alkali Act 1863 and similar legislation in other countries, the excess HCl was often vented into the air.
An early exception was the Bonnington Chemical Works where, in 1830, the Hydrochloride 20% began to be captured and the hydrochloric acid produced was used in making sal ammoniac (ammonium chloride).

After the passage of the act, soda ash producers were obliged to absorb the waste gas in water, producing hydrochloric acid on an industrial scale.
Hydrochloride 20% is usually prepared industrially by dissolving hydrogen chloride in water.
Hydrochloride 20% can be generated in many ways, and thus several precursors to hydrochloric acid exist.

The large-scale production of Hydrochloride 20% is almost always integrated with the industrial scale production of other chemicals, such as in the chloralkali process which produces hydroxide, hydrogen, and chlorine, the latter of which can be combined to produce HCl.
Hydrochloride 20% itself is used in themanufacture of pharmaceutical hydrochlorides, chlorine, vinylchloride from acetylene; alkyl chlorides from olefins; arsenictrichloride from arsenic trioxide; in the chlorination of rubber;as a gaseous flux for babbitting operations; and in organic syn-thesis involving isomerization, polymerization, alkylation, andnitration reactions. The acid is used in the production of fertili-zers,dyes, dyestuffs, artificial silk, and paint pigments; inrefining edible oils and fats; in electroplating; leather tanning;ore refining; soap refining; petroleum extraction; pickling ofmetals; and in the photographic, textile, and rubber industries.

Hydrochloride 20% has been used as a choking/pulmonary agent.
Dissociation into ions is extensive and Hydrochloride 20% shows the typical properties of a strong acid.
Hydrochloride 20% reacts with carbonates to give carbon dioxide and yields hydrogen when reacted with all but the most unreactive metals.

Hydrochloride 20% is used in the manufacture of dyes, drugs, and photographic materials.
Hydrochloride 20% is also used to pickle metals, i.e. clean the surface prior to electroplating.
Hydrochloride 20% donates protons with ease and is the strongest of the hydrohalic acids.

The concentrated acid is oxidized to chlorine by such agents as potassium manganate(VII) and manganese( IV) oxide.
Hydrochloride 20% is widely used as an acidifying agent, in a variety of pharmaceutical and food preparations.
Hydrochloride 20% may also be used to prepare dilute hydrochloric acid, which in addition to its use as an excipient has some therapeutic use, intravenously in the management of metabolic alkalosis, and orally for the treatment of achlorhydria.

Of the common strong mineral acids in chemistry, Hydrochloride 20% is the monoprotic acid least likely to undergo an interfering oxidation-reduction reaction.
Hydrochloride 20% is one of the least hazardous strong acids to handle; despite its acidity, it contains the non-reactive and non-toxic chloride ion.
Intermediate-strength hydrochloric acid solutions are quite stable upon storage, maintaining their concentrations over time.

These attributes, plus the fact that it is available as a pure reagent, make hydrochloric acid an excellent acidifying reagent.
Hydrochloride 20% is also inexpensive.
Bacteria quickly suffocate to death after using Poly Hexamethylenebiguanide Hcl (PHMB) 20%.

At the same time, because this product is a polymer structure, which can improve the effective activity of guanidine group, the bactericidal effect of Hydrochloride 20% soution is much higher than other guanidine compounds (such as chlorhexidine). Due to the special bactericidal mechanism of this product, all kinds of bacteria will not be resistant to it, which has been confirmed by the experiments of foreign authoritative testing institutions.

After the solution of Hydrochloride 20% is dried, a polymer thin layer of disinfectant is formed on the surface of the object, which can keep the state of the object after sterilization and prevent the secondary pollution of the object.
Generally, the surfaces treated with aqueous solution of this product will remain sterile for up to three months.

History:
Hydrochloride 20% is a strong, corrosive acid that results when the gas hydrogen chloride dissolves in water.
Ancient alchemists prepared hydrochloric acid and Jabbar ibn Hayyan, known in Latin as Geber (721–815), is credited with its discovery around the year 800.
The original method of preparation involved reacting salt with sulfuric acid, producing sodium hydrogen sulfate and hydrogen chloride gas.

The hydrogen chloride gas is captured and dissolved in water to produce Hydrochloride 20%.
Hydrochloride 20% was formerly called muriatic acid.
Terms such as muriatic and muriate were used in association with chloride substances before the discovery and nature of chlorine were fully understood.

The Latin term muriaticus means pickled from muri, which is the Latin term for brine.
Chlorides were naturally associated with seawater salt solutions, as chloride is the principal ion in seawater.
In the early tenth century, the Persian physician and alchemist Abu Bakr al-Razi conducted experiments with sal ammoniac (ammonium chloride) and vitriol (hydrated sulfates of various metals), which he distilled together, thus producing the gas hydrogen chloride.

In doing so, al-Razi may have stumbled upon a primitive method for producing Hydrochloride 20%.
However, Hydrochloride 20% appears that in most of his experiments al-Razi disregarded the gaseous products, concentrating instead on the color changes that could be effected in the residue.
According to Robert P. Multhauf, hydrogen chloride was produced many times without clear recognition that, by dissolving it in water, hydrochloric acid may be produced.

Production:
Hydrochloride 20% can be produced by several methods.
Hydrochloride 20% is obtained from the reaction of sodium chloride and sulfuric acid in a cast iron retort at elevated temperature.
Although reaction starts at 150°C, the complete reaction occurs at about 600°C: 2NaCl + H2SO4→ Na2SO4 + 2HCl

Hydrochloride 20% also is made by the Hargreaves process in which a mixture of salt, sulfur dioxide, oxygen, and water are heated at elevated temperatures, between 430 to 540°C.
The reaction is exothermic and becomes selfsustaining: 4NaCl + SO2 + O2 + 2H2O→ 2Na2SO4 + 4HCl
Hydrochloric acid may be produced by hydrolysis of metal chlorides such as titanium(IV) chloride: TiCl4 + 2H2O →TiO2 + 4HCl

High purity HCl for commerce is made directly from hydrogen and chlorine: H2 + Cl2→ 2HCl
The above reaction is highly exothermic.
The stoichiometric proportion of gaseous mixture at equilibrium flame temperature is cooled to 200°C, whereupon the elements combine rapidly to form HCl with over 99% yield.

HCl also may be prepared by several other methods including thermal dissociation of aluminum chloride hexahydrate, AlCl3•6H2O, and as a by-product of manufacturing many organic compounds.
Crude HCl gas mixture may be purified by cooling and drying over concentrated sulfuric acid, which also removes organic unsaturated contaminants.
Organic contaminants may be removed further by adsorption over molecular sieves, polystyrene foam, active carbon, or scrubbing with a high-boiling point organic liquid.

Commercial grade, concentrated hydrochloric acid is about 37.5% HCl by weight and has a normality of 12 and specific gravity 1.19.
Hydrogen chloride gas may be stored in steel cylinders free of contaminants.
Monel, pure nickel, or its alloy, inconel, may also be used for storage and transportation up to 500°C.

Hydrochloric acid may be stored in glass bottles or in containers made up of tantalum or tantalum-molybdenum alloys, or other alloys of zirconium, molybdenum, and tungsten.
The traditional method of preparation of hydrochloric acid is the reaction of metal chlorides, especially sodium chloride with sulfuric acid (see the first reaction described).
Hydrochloric acid is also produced by direct synthesis from its elements.

In the chlorine-alkali industry, electrochemical reactions produce elemental chlorine and hydrogen, which can then be combined to give hydrogen chloride: Cl2(g) + H2(g) 2HCl(g).
Hydrogen chloride is then dissolved in water to produce hydrochloric acid.
By far, the most common method of producing hydrochloric acid involves its production as a by-product in chlorination reactions.

This has curtailed this source of hydrochloric acid.
The production of other common industrial organic chemicals such as Teflon, perchloroethylene, and polyvinyl chloride result in the production of hydrogen chloride.
The production of hydrochloric acid in polyvinyl chloride production takes place when ethylene is chlorinated: C2H4(g) + Cl2(g) C2H4Cl2(g) C2H4Cl2(g)(g) C2H3Cl(g) + HCl(g).

Uses:
Hydrochloride 20% is one of the most important industrial chemicals and has numerous applications.
Both anhydrous hydrogen chloride and aqueous acid are used to produce a large number of chloride salts.
The acid also is a common laboratory reagent.

Some major applications of Hydrochloride 20% include processing of ores and extraction of metals from their minerals; in metal cleaning, particularly in steel pickling to dissolve oxide impurities; production of alumina, titanium dioxide, and other metal oxides by various hydrometallurgical processes; production of hydrogen; synthesis of chlorine dioxide; removal of heavy metal impurities from carbon black; activation of bentonite clays; etching of concrete surfaces for finishing operations; and as a catalyst in several organic reactions such as inversion of sugar, hydrolysis of starch to obtain sugar syrup, and esterification of aromatic acids.
Anhydrous Hydrochloride 20% gas is used to produce phosphonium chloride, PH4Cl, which is a flame retardant for cotton textiles. Other major applications include manufacture of a number of high purity metal chlorides, ammonium chloride, chlorosulfuric acid; recovery of waste metals; preparation of alkyl chlorides and chloroacetic acids; and as a chlorinating agent in organic syntheses.

Rubber Hydrochloride 20%, which results from the treatment of natural rubber with hydrogen chloride, can be cast in film from solutions.
Such rubber hydrochloride films provide a strong, water resistant packaging material for meats and other foods, paper products, and textiles.
Pickling is a metal treatment process used to prepare metal surfaces for subsequent processing such as galvanizing or extrusion.

In the iron industry, pickling involves immersing iron and steel products in vats of diluted hydrochloric acid.
This removes oxides, dirt, and grease.
Oil well acidizing involves injecting Hydrochloride 20% down well holes to dissolve limestone and carbonate formations.

This expands existing fissures and creates new fissures to open channels for oil extraction.
Hydrochloride 20% is also used extensively in pharmaceuticals and the food industry.
When it is listed after a drug name, the drug was produced by combining a free base and Hydrochloride 20% to produce a hydrochloride salt.

Drugs delivered as hydrochloride salts rather than free bases are more soluble in water than free forms of the drugs, tend to be more stable, are solids, and are often more compatible with the chemistry of the digestive system.
In the food industry Hydrochloride 20% is used in the production of gelatin and sodium glutamate, to convert cornstarch to syrup, to refine sugar, and as an acidulant.

Hydrochloride 20% is one of the most widely used acids and a common laboratory reagent.
Hydrochloride 20% is used in the manufacture of chlorides, in the pickling and cleaning of metal products, as a processing agent for manufacturing various food products, as a cleaning agent, in organic synthesis, and for neutralizing alkalies.
Hydrochloride 20% is a fire-effluent gas.

Firefighters are frequently exposed to significant concentrations of HCl.
Hydrochloride 20% arereleased from the oxidative thermal degradation of polyvinyl chloride (PVC)-derivedfiberglass, cotton, and jute brattices in mines.
The gas is absorbed by water droplets,entrapped in soot particles, causing risk ofexposure of the acid to the eyes, throat,and lungs of mine workers.

Hydrochloride 20% is an acid that is the aqueous solution of hydro- gen chloride of varying concentrations.
Hydrochloride 20% is miscible with water and with alcohol.
Hydrochloride 20% is used as an acidulant and neutralizing agent.

In the production of chlorides; refining ore in the production of tin and tantalum; for the neutralization of basic systems; as laboratory reagent; hydrolyzing of starch and proteins in the preparation of various food products; pickling and cleaning of metal products; as catalyst and solvent in organic syntheses.
Also used for oil- and gas-well treament and in removing scale from boilers and heat-exchange equipment.
Hydrochloride 20% is a highly corrosive liquid, emitting a pungent odor and fumes in moist air.

Concentrated Hydrochloride 20% is one of the strongest acids and thus any desired pH from 0 to 7 can be easily achieved with the required dosage.
Hydrochloride 20% is seldom used in mineral flotation.
The largest use is in hydrometallurgical processes and the pickling of hot rolled steel.

In some cases, Hydrochloride 20% is used for decoating iron-stained mineral surfaces before flotation.
Piping, valves, and other equipment used in direct contact with anhydrous hydrogen chloride should be of stainless steel or of cast or mild steel.
Carbon steel may be used in some components, but only if their temperature is controlled to remain below about 265°F (l29°C).

In the presence of moisture, however, hydrogen chloride will corrode most metals.
They are often employed to convert basic drugs into their more stable and water-soluble salt forms, enhancing their bioavailability and facilitating drug delivery.
Hydrochloride 20%s are utilized in the formulation of tablets, capsules, injections, and other dosage forms to improve drug stability, solubility, and overall efficacy.

They may also be used as pH adjusters or buffering agents in pharmaceutical formulations to maintain optimal pH levels.
Hydrochloride 20%s serve as reagents, catalysts, or intermediates in various chemical synthesis processes, including organic synthesis, polymerization reactions, and material science applications.
Hydrochloride 20% is commonly used in laboratory research for experimental purposes, such as chemical reactions, biological assays, and analytical testing.

Hydrochloride 20% is used in water treatment processes to adjust pH levels, remove impurities, or disinfect water supplies.
Hydrochloride 20% find applications in diverse industrial processes, including metal surface treatment, electroplating, textile dyeing, and manufacturing of chemicals and polymers.
In the food industry, Hydrochloride 20% may be used as acidity regulators, preservatives, or flavor enhancers in food and beverage products.

Some cleaning products, such as toilet bowl cleaners and descaling agents, contain hydrochloride salts for their acidic properties, which help dissolve mineral deposits and remove stains.
Hydrochloride 20% is also utilized in veterinary medicine for formulating medications and supplements for animals.
Hydrochloride 20% is employed as reference standards, calibration solutions, or titrants in analytical chemistry techniques for quantitative analysis and quality control purposes.

In the cosmetics and personal care industry, Hydrochloride 20% may be used in formulations of skincare products, hair care products, and toiletries for various purposes, such as pH adjustment or chemical stabilization.
Hydrochloride 20% is sometimes used as preservatives in certain products, such as cosmetics and toiletries, to prevent microbial growth and extend shelf life.
In agriculture, Hydrochloride 20% may be used in fertilizers or soil amendments to provide essential nutrients to plants or to adjust soil pH levels.

Some photographic processes utilize Hydrochloride 20% as part of developing solutions or fixing agents to create images on photographic film or paper.
Hydrochloride 20% can be involved in the leather tanning process, where they help to preserve and soften animal hides for use in leather products.
In wastewater treatment facilities, Hydrochloride 20% may be used as coagulants or flocculants to aid in the removal of contaminants and pollutants from water.

Hydrochloride 20% is used in metal cleaning and etching processes to remove rust, scale, or other surface impurities from metal surfaces prior to finishing or plating.
In electronics manufacturing, Hydrochloride 20% is sometimes used in chemical etching processes to selectively remove material from metal surfaces to create circuit patterns or microstructures.
Hydrochloride 20% may serve as analytical reagents or standards in laboratory analysis techniques such as spectrophotometry, chromatography, or titration for quantitative chemical analysis

Some Hydrochloride 20%, such as calcium chloride or magnesium chloride, are used as deicing agents on roads and sidewalks to melt ice and snow during winter months.
Certain dry chemical fire extinguishers contain Hydrochloride 20% as part of their extinguishing agent to help suppress fires involving combustible metals.

Health Hazard:
Gas concentrations of 50 to 100 ppm are tolerable for 1 hour.
Concentrations of 1,000 to 2,000 ppm are dangerous, even for brief exposures.
More severe exposures will result in serious respiratory distress and prolonged exposures will result in death.

Mists of Hydrochloride 20% are considered less harmful than anhydrous hydrochloric acid, because droplets have no dehydrating action.
Individuals with respiratory problems and digestive diseases may be adversely affected by low level exposures to the gas or mist.
Exposures to Hydrochloride 20% cause severe health effects and corrosive reactions.

Concentrated Hydrochloride 20% forms acidic mists.
Both the mist and the solution have a corrosive effect on human tissue, with the potential to damage the respiratory organs, eyes, skin, and intestines.
Inhalation of vapors can cause coughing, choking, infl ammation of the nose, throat, and upper respiratory tract, and in severe cases, pulmonary edema, circulatory failure, and death.

Accidental ingestion and/or swallow- ing of Hydrochloride 20% at workplaces causes immediate pain and burns of the mouth, throat, esophagus, and gastrointestinal tract.
Hydrochloride 20% also causes nausea, vomiting, and diar- rhea, and in severe cases, death.
Any kind of contact of the skin surfaces to Hydrochloride 20% causes redness, pain, and severe skin burns.

Concentrated solutions of hydrochloric acid cause deep ulcers and discolor the skin.
Vapors of hydrochloric acid cause irritat- ing effects to the eyes and eye damage, leading to severe burns and permanent eye dam- age.
Long-term exposures to concentrated vapors of Hydrochloride 20% cause erosion of the teeth.

Occupational workers and persons with pre-existing skin disorders or eye disease are more susceptible to the effects of Hydrochloride 20%.
Hydrochloride 20% and hydrogen chloride gas are highly corrosive substances that may cause severe burns upon contact with any body tissue.
The aqueous acid and gas are strong eye irritants and lacrimators.

Contact of conc Hydrochloride 20% or concentrated HCl vapor with the eyes may cause severe injury, resulting in permanent impairment of vision and possible blindness, and skin contact results in severe burns.
Ingestion can cause severe burns of the mouth, throat, and gastrointestinal system and can be fatal.
Inhalation of hydrogen chloride gas can cause severe irritation and injury to the upper respiratory tract and lungs, and exposure to high concentrations may cause death.

HCl gas is regarded as having adequate warning properties
Hydrochloride 20% has not been found to be carcinogenic or to show reproductive or developmental toxicity in humans
Concentrated Hydrochloride 20% is a corrosivesubstance that can cause severe burns.

Ingestion can produce corrosion of themouth, gastrointestinal tract, and stomach,and diarrhea.
Hydrogen chloride is a toxic gas with acharacteristic pungent odor.
Inhalation cancause coughing, choking, and irritation ofthe mucous membranes.

Exposure to concentrations at >5 ppm in air can be irritating and disagreeable to humans.
A short exposure to 50 ppmmay cause irritation of the throat. Workersexposed to hydrochloric acid were found tosuffer from gastritis and chronic bronchitis.
Rats exposed continuously to a hydrogen chloride atmosphere died after physicalincapacitation.

Hartzelland coworkers (1987) have studied thetoxicological effects of smoke containinghydrogen chloride in fire gases.
The lethality of PVC smoke was high but not entirelydue to the hydrogen chloride produced.
Postexposure death in rats was observed afterpulmonary irritation caused by high concentration of HCl.

Lethality in the presenceof carbon monoxide may be additive.
Inanother paper, Hartzell and associates (1988)reported that guinea pigs were three timesas sensitive as rats to HCl exposure.
Hydrochloride 20% produced bronchoconstriction in animals andshowed additive toxicity with CO at relatively high concentrations of the latter.

Fire Hazard:
Fire may produce irritating or poisonous gases.
Containers may explode in heat of fire.
At high temperatures, Hydrochloride 20% decomposes into hydrogen and chlorine.

The following materials should be avoided: Mercuric sulfate violent reaction with gaseous Hydrochloride 20% at 250F.
Sodium reacts vigorously with gaseous Hydrochloride 20%.
Acetic anhydride, 2-aminoethanol, ammonium hydroxide, chlorosulfonic acid, ethylene diamine, ethyleneimine, oleum, propiolactone, sodium hydroxide, sulfuric acid, and vinyl acetate increase in temperature and pressure when mixed with hydrochloric acid.

Calcium phosphide energetic reaction with Hydrochloride 20%.
Silver perchlorate and carbon tetrachloride when mixed in combination with Hydrochloride 20% forms a compound that detonates at 105F.
Formaldehyde when mixed with Hydrochloride 20% forms a human carcinogen.

Material reacts violently with bases and is corrosive with the generation of heat.
Reacts with base metals, forming combustible gas (hydrogen).

Reacts violently with strong oxidants forming toxic gas (chlorine).
Avoid heat; at high temperatures Hydrochloride 20% will decompose into hydrogen and chlorine.


Hydrochloric acid
HYDROCINNAMALDEHYDE N° CAS : 104-53-0 Nom INCI : HYDROCINNAMALDEHYDE Nom chimique : 3-Phenylpropionaldehyde N° EINECS/ELINCS : 203-211-8 Ses fonctions (INCI) Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
HYDROCINNAMALDEHYDE
HYDROFLUORIC ACID; Hydrogen Fluoride; Etching Acid; AHF; Fluorohydric Acid; Fluoric acid; HF Acid; Acide Fluorhydrique (French); Acido Fluoridrico (Italian); Fluorowodor (Polish); Fluorwasserstoff (German); Fluorwaterstof (Dutch); cas no: 7664-39-3
HYDROFLUORIC ACID
Hydrofluoric Acid Uses of Hydrofluoric acid Production of organofluorine compounds The principal use of hydrofluoric acid is in organofluorine chemistry. Many organofluorine compounds are prepared using HF as the fluorine source, including Teflon, fluoropolymers, fluorocarbons, and refrigerants such as freon. Many pharmaceuticals contain fluorine. Production of inorganic fluorides of Hydrofluoric acid Most high-volume inorganic fluoride compounds are prepared from hydrofluoric acid. Foremost are Na3AlF6, cryolite, and AlF3, aluminium trifluoride. A molten mixture of these solids serves as a high-temperature solvent for the production of metallic aluminium. Other inorganic fluorides prepared from hydrofluoric acid include sodium fluoride and uranium hexafluoride. Properties of Hydrofluoric acid Chemical formula HF (aq) Appearance Colorless liquid Density 1.15 g/mL (for 48% soln.) Acidity (pKa) 3.17 Wet etching tanks It is used in the semiconductor industry as a major component of Wright Etch and buffered oxide etch, which are used to clean silicon wafers. In a similar manner it is also used to etch glass by treatment with silicon dioxide to form gaseous or water-soluble silicon fluorides. Hydrofluoric acid can also be used to polish and frost glass. SiO2 + 4 HF → SiF4(g) + 2 H2O SiO2 + 6 HF → H2SiF6 + 2 H2O A 5% to 9% hydrofluoric acid gel is also commonly used to etch all ceramic dental restorations to improve bonding. For similar reasons, dilute hydrofluoric acid is a component of household rust stain remover, in car washes in "wheel cleaner" compounds, in ceramic and fabric rust inhibitors, and in water spot removers. Because of its ability to dissolve iron oxides as well as silica-based contaminants, hydrofluoric acid is used in pre-commissioning boilers that produce high-pressure steam. Hydrofluoric acid is also useful for dissolving rock samples (usually powdered) prior to analysis. In similar manner, this acid is used in acid macerations to extract organic fossils from silicate rocks. Fossiliferous rock may be immersed directly into the acid, or a cellulose nitrate film may be applied (dissolved in amyl acetate), which adheres to the organic component and allows the rock to be dissolved around it. Oil refining In a standard oil refinery process known as alkylation, isobutane is alkylated with low-molecular-weight alkenes (primarily a mixture of propylene and butylene) in the presence of an acid catalyst derived from hydrofluoric acid. The catalyst protonates the alkenes (propylene, butylene) to produce reactive carbocations, which alkylate isobutane. The reaction is carried out at mild temperatures (0 and 30 °C) in a two-phase reaction. Production of Hydrofluoric acid Hydrofluoric acid was first prepared in 1771, by Carl Wilhelm Scheele. It is now mainly produced by treatment of the mineral fluorite, CaF2, with concentrated sulfuric acid at ca. 265 °C. CaF2 + H2SO4 → 2 HF + CaSO4 The acid is also a by-product of the production of phosphoric acid from apatite/fluoroapatite. Digestion of the mineral with sulfuric acid at elevated temperatures releases a mixture of gases, including hydrogen fluoride, which may be recovered. Because of its high reactivity toward glass, hydrofluoric acid is stored in plastic containers. Hydrofluoric acid can be found in nature; it is released in volcanic eruptions. Properties of Hydrofluoric acid In dilute aqueous solution hydrogen fluoride behaves as a weak acid, Infrared spectroscopy has been used to show that, in solution, dissociation is accompanied by formation of the ion pair H3O+·F−. H2O + 2HF ⇌ H+ + F− + H3O+⋅F−, pKa = 3.17 This ion pair has been characterized in the crystalline state at very low temperature. Further association has been characterized both in solution and in the solid state. HF + F− ⇌ HF2− log K = 0.6 It is assumed that polymerization occurs as the concentration increases. This assumption is supported by the isolation of a salt of a tetrameric anion H3F4− and by low-temperature X-ray crystallography. The species that are present in concentrated aqueous solutions of hydrogen fluoride have not all been characterized; in addition to HF2− which is known the formation of other polymeric species, Hn-1Fn−, is highly likely. The Hammett acidity function, H0, for 100% HF is estimated to be between −10.2 and −11. which is comparable to the value −12 for sulfuric acid. Solutions of hydrofluoric acid attack glass, so they are stored and used in vessels made of teflon. They attack human skin, so must be handled with great care: see #Health and Safety, below. Acidity of Hydrofluoric acid Unlike other hydrohalic acids, such as hydrochloric acid, hydrogen fluoride is only a weak acid in dilute aqueous solution. This is in part a result of the strength of the hydrogen–fluorine bond, but also of other factors such as the tendency of hydrofluoric acid, H2O, and F− anions to form clusters. At high concentrations, hydrofluoric acid molecules undergo homoassociation to form polyatomic ions (such as bifluoride, HF−2) and protons, thus greatly increasing the acidity. This leads to protonation of very strong acids like hydrochloric, sulfuric, or nitric when using concentrated hydrofluoric acid solutions. Although hydrofluoric acid is regarded as a weak acid, it is very corrosive, even attacking glass when hydrated. The acidity of hydrofluoric acid solutions varies with concentration owing to hydrogen-bond interactions of the fluoride ion. Dilute solutions are weakly acidic with an acid ionization constant Ka = 6.6×10−4 (or pKa = 3.18), in contrast to corresponding solutions of the other hydrogen halides, which are strong acids (pKa < 0). Concentrated solutions of hydrogen fluoride are much more strongly acidic than implied by this value, as shown by measurements of the Hammett acidity function H0(or "effective pH"). The H0 for 100% hydrofluoric acid is estimated to be between −10.2 and −11, comparable to the value −12 for sulfuric acid. In thermodynamic terms, hydrofluoric acid solutions are highly non-ideal, with the activity of hydrofluoric acid increasing much more rapidly than its concentration. The weak acidity in dilute solution is sometimes attributed to the high H—F bond strength, which combines with the high dissolution enthalpy of hydrofluoric acid to outweigh the more negative enthalpy of hydration of the fluoride ion. Paul Giguère and Sylvia Turrell have shown by infrared spectroscopy that the predominant solute species in dilute solution is the hydrogen-bonded ion pair H3O+·F−. H2O + HF ⇌ H3O+⋅F− With increasing concentration of hydrofluoric acid the concentration of the hydrogen difluoride ion also increases. The reaction 3 HF HF2− + H2F+ is an example of homoconjugation. Health and safety of Hydrofluoric acid In addition to being a highly corrosive liquid, hydrofluoric acid is also a powerful contact poison. Because of the ability of hydrofluoric acid to penetrate tissue, poisoning can occur readily through exposure of skin or eyes, or when inhaled or swallowed. Symptoms of exposure to hydrofluoric acid may not be immediately evident, and this can provide false reassurance to victims, causing them to delay medical treatment. Despite having an irritating odor, hydrofluoric acid may reach dangerous levels without an obvious odor. Hydrofluoric acid interferes with nerve function, meaning that burns may not initially be painful. Accidental exposures can go unnoticed, delaying treatment and increasing the extent and seriousness of the injury. Symptoms of hydrofluoric acid exposure include irritation of the eyes, skin, nose, and throat, eye and skin burns, rhinitis, bronchitis, pulmonary edema (fluid buildup in the lungs), and bone damage. Popular culture of Hydrofluoric acid In the series 4 episode 'Chain reaction' of the British medical drama Casualty a road traffic collision results in a spillage of hydrofluoric acid testing the resources of the department and resulting in the death of a police officer and severe burns to other motorists. This episode realistically depicts the fire service response to a chemical spillage In an episode of Breaking Bad titled "Cat's in the Bag...", Jesse Pinkman uses hydrofluoric acid to dissolve the body of Emilio Koyama. In another episode, "Box Cutter", Walter White and Jesse Pinkman use hydrofluoric acid to dissolve the body of Victor. In the film Saw VI, hydrofluoric acid is used for killing William Easton. In the film Jigsaw, Carly is killed by hydrofluoric acid injected into her bloodstream. In an episode of Titans titled "Jason Todd", a young Dick Grayson claims that his parents' murderer used hydrofluoric acid to burn their trapeze ropes. In a trio of segments of the videogame Zero Time Dilemma titled "First Come, First Saved", each of the three teams of participants are given the option to press a button that activates a hydrofluoric acid shower that pours over the other two teams. The corrosion process of the acid is both described and depicted as being fast enough to melt everything from metal and glass to the entire body of a sizable adult male in a matter of seconds, leaving only small amounts of tissue behind. Hydrofluoric Acid: What You Need to Know Incidents involving hydrogen fluoride, or hydrofluoric acid, are not common, but the consequences of exposure to this compound by any means can be devastating. This little-known acid has unique properties that make it extremely dangerous to emergency personnel and others. Frequently mistaken for or confused with hydrochloric acid, HF should be referred to as Hydrofluoric acid. I became interested in Hydrofluoric acid while working in an oil refinery that uses it as a catalyst to make high-octane gasoline. As a paramedic, I found the effects of Hydrofluoric acid on the human body fascinating. I learned what I could about it and began teaching Hydrofluoric acid safety to my coworkers. Then, in 2001, I was involved in an Hydrofluoric acid incident in which I was seriously exposed. I had been sprayed with anhydrous Hydrofluoric acid at approximately 150 pounds of pressure when a ¾" pipe broke at an ell as I was preparing to remove a plug. The Hydrofluoric acid had eaten the threads inside the ell and the weight of my pipe wrench caused the damaged pipe to give way, spraying both my legs just below my groin, and my right forearm. That exposure began a battle for my life that continues today. Luckily, our local EMS and emergency facility had been trained on the dangers of this acid and proper treatment. Many EMS and ER personnel have probably never heard of this dangerous compound, but all emergency services, fire or law enforcement personnel who operate near and may be called to respond to any facility that uses or manufactures a form of Hydrofluoric acid should receive yearly training on treatment for Hydrofluoric acid exposure. This information should be available from your county LEPC. Anhydrous hydrogen fluoride (Hydrofluoric acid) is an inorganic, corrosive compound with many industrial and commercial uses. It is manufactured by heating purified fluorspar (calcium fluoride) with concentrated sulfuric acid to produce the gas, which is then condensed by cooling or dissolving in water. It can also be refined as a by-product of the production of phosphoric acid, which is derived from the mineral apatite. Apatite sources typically contain a small amount of fluorite. The acid hydrolysis of fluorite-containing minerals generates an impure gas stream consisting of sulfur dioxide, water and Hydrofluoric acid. Separating gases from solids and treating them with sulfuric acid and oleum produces anhydrous Hydrofluoric acid. Hydrofluoric acid can also be released when other fluoride-containing compounds, such as ammonium fluoride, are combined with water or when certain plastics are exposed to fire conditions, creating carbonyl fluoride (the fluorine analog of phosgene). HYDROFLUORIC ACID FAST FACTS Hydrogen fluoride is available commercially either in an anhydrous (water-free) state or in water solutions of various concentrations. At higher concentrations, Hydrofluoric acid is a colorless gas or a fuming liquid. Hydrofluoric acid may be known as Hydrogen fluoride (UN 1052), hydrofluoric acid (UN 1790) or fluorohydric acid. Identification numbers are CAS number 7664-39-3, UN: 1052 or RTECS: MW7875000. Main Manufacturers/main importers are DuPont (US), Allied (US) and Honeywell (US). Its physical properties are: Molecular weight: 10 Boiling point: Gas at temperatures above 19°C Auto-ignition: Not relevant Vapor pressure: 150mm (70% solution at 26.7°C); 70mm (70% solution at 20.0°C) Solubility: Aqueous solutions to 70% Explosive limits: Not applicable--non-flammable (BLEVE hazard if container subjected to fire conditions) Shipping name: Hydrogen fluoride, anhydrous (1052), hydrofluoric acid, with not more than 60% strength (1790) Identification number: 1052 (hydrogen fluoride, anhydrous) (Guide 125), 1790 (hydrofluoric acid) (Guide 157) Hazardous class or division: 8 (1052) Subsidiary hazardous class or division: 6.1, Inhalation hazard (1790) Label: Corrosive, Poison (toxic) (1052), Corrosive, Poison (Toxic), Inhalation Hazard (1790) Hydrogen fluoride is used in solution form in glass and metal etching, industrial and home cleaners and rust removers, and in manufacturing electronics. Full strength, it is used to manufacture high-octane fuels in oil refineries. Other major industrial uses of hydrogen fluoride include synthesis of fluorocarbons (e.g., freon and Teflon) and production of aluminum fluoride and synthetic cryolite for use in aluminum refining. It is also employed in refining uranium for use as a nuclear fuel, in manufacturing various organic chemicals, in producing stainless steel, and for various other applications such as: Propellants and solvents Insecticide and fertilizer production Manufacture and reduction of chlorides Brewery to control fermentation Fabric industry for stain removal Leather industry for tanning Drug and dye production Manufacture of semiconductors. Present household uses include: Rust remover Aluminum brighteners Heavy-duty cleansers. Hydrofluoric acid is a colorless fuming liquid below 67°F (19.4°C), or a colorless gas. When hydrogen fluoride is combined with water it is known as hydrofluoric acid, a colorless liquid, which in low concentrations is visually indistinguishable from water. Hydrofluoric acid that is more than 40% hydrogen fluoride fumes in air. Hydrofluoric acid can be used for intra-oral repair of restorations. Contamination of tooth substrate with hydrofluoric acid cannot always be avoided. /The study objective was/ to investigate the bonding effectiveness to hydrofluoric acid contaminated dentin by, micro-tensile bond strength testing, SEM and TEM. For this study, 15 molar teeth were used of which dentin surfaces were subjected to five, different etching procedures. Group A, 37.5% phosphoric acid (Kerr Gel) (control group); group B, 37.5% phosphoric acid followed by 3% hydrofluoric acid (DenMat); group C, 37.5% phosphoric acid, followed by 9.6% hydrofluoric acid (Pulpdent); group D, 3% hydrofluoric acid followed by 37.5%, phosphoric acid; group E, 9.6% hydrofluoric acid followed by 37.5% phosphoric acid. After the bonding procedure (OptiBond FL, Kerr) a composite resin build-up (Clearfil AP-X, Kuraray), was made. After 1 week storage, specimens were prepared for micro-tensile bond testing, SEM- and, TEM-analysis. Data were analyzed using ANOVA and post hoc Tukey's HSD (p<0.05). In the control group (solely phosphoric acid), the mean microTBS was 53.4+/-10.6 MPa, which was, significantly higher than any hydrofluoric acid prepared group (group A versus groups B-E, p<0.001). No, significant differences in microTBS were found between the 3% and 9.6% hydrofluoric acid groups: group B versus group C (13.5+/-5.5 MPa and 18.7+/-4.3 MPa, respectively) or group D versus group E (19.9+/-6.8 MPa and 20.3+/-4.1 MPa, respectively). Due to its adverse effect on the bond strength of composite to dentin, contact of hydrofluoric acid to dentin should be avoided. Hydrogen fluoride is a colorless, fuming liquid or gas with a strong, irritating odor. Hydrofluoric acid is usually shipped in steel cylinders as a compressed gas. Hydrogen fluoride readily dissolves in water to form colorless hydrofluoric acid solutions; dilute solutions are visibly indistinguishable from water. Ocular tissues are extremely sensitive to hydrofluoric acid. Concentrations as low as 5 mg/L (5 ppm) may produce irritation to the eye. Although the protein aqueous precipitation of coagulation necrosis limits the penetration of other inorganic acids, hydrofluoric acid is able to penetrate the ocular tissues and produces severe damage to ocular structures. Lacrimation, pain, and conjunctival injection are early symptoms of hydrofluoric acid exposure. Corneal and conjunctival epithelium may be denuded, leading to edema and ischemia. Corneal vascularization and scarring may result. Toxicity may be delayed by up to 4 days after dilute exposures. Global perforation has also been reported. Hydrofluoric acid is an irritant to the mucosa of the upper and lower portions of the respiratory tract. As in ocular tissues, concentrations as low as 5 mg/L (5 ppm) may produce irritation to the nasal mucosa. When hydrofluoric acid is present in concentrations greater than 48%, the solution fumes, adding to the volatile airborne fraction. Mucosal edema, bronchospasm, bronchorrhea, wheezing, atelectasis, and airways obstruction may result. A chemical tracheobronchitis or pneumonitis, either of which may be hemorrhagic, and pulmonary edema may follow. Onset of signs and symptoms may be immediate, with death reported in as little as 30 minutes after exposure, or they may not appear for several days. Symptoms in survivors may be sustained for greater than 1 year. A waste containing hydrofluoric acid may (or may not) be characterized a hazardous waste following testing for corrosivity characteristics as prescribed by the Resource Conservation and Recovery Act (RCRA) regulations. Hydrogen fluoride/hydrofluoric acid has not been classified as a carcinogen. It is not known whether chronic or repeated exposure to hydrogen fluoride/hydrofluoric acid increases the risk of reproductive toxicity or developmental toxicity. Chronic or repeated exposure to hydrogen fluoride/hydrofluoric acid has been associated with fluorosis, mottling of the teeth, weight loss, malaise, anemia, leukopenia, discoloration of teeth, osteosclerosis, skeletal changes such as increased bone density of the spine and pelvis, calcification of ligaments, hyperostosis, and liver or kidney damage. A chemical polishing soln consisting of nitric acid and hydrofluoric acid (1 vol each) and glycerol (2 vols) generated enough pressure during storage for 4 hr to rupture the closed plastics container. This was caused by gas evolution from oxidation of glycerol by the strongly oxidizing mixture. A mixture of nitric acid (80 mL), hydrofluoric acid (80 mL) and glycerol (240 mL) was used immediately for etching metal, again the next day, and then stored in a stoppered flask. After some 2-3 days, the stopper was ejected and approx 300 mL was sprayed around the fume cupboard containing the flask. The metals dissolved during use further destabilize the mixture, which should not be stored under any circumstances. Mixtures of the 3 acids /hydrofluoric acid, lactic acid, and nitric acid/, used as metal polishing solutions, are unstable and should not be stored. Lactic acid and nitric acid react autocatalytically after a quiescent period, attaining a temp of about 90 °C with vigorous gas evolution after about 12 hr. A chemical polishing mixture /of hydrofluoric acid, propylene glycol, silver nitrate, and nitric acid/ was put into a closed glass bottle which burst 30 min later, and formation of silver fulminate was suggested. However, in absence of the silver salt such mixtures evolve gas and should not be stored in any event, especially after use for metal polishing, when the dissolved metal(s) tend to further destabilize the mixture. The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article. Hydrogen fluoride, anhydrous; hydrofluoric acid solution, with more than 60% hydrogen fluoride; and hydrofluoric acid solution, with not more than 60% hydrogen fluoride are included on the dangerous goods list. Hydrofluoric acid is an indirect food additive for use only as a component of adhesives. Hydrofluoric acid is a dangerous inorganic acid that can cause local corrosion and systemic effects by ongoing absorption via the skin, mucosae, respiratory tract and digestive system. Recently, a serious toxic leak of low-concentration hydrofluoric acid solution occurred in the Pujiang area of Zhejiang Province, China. This accident resulted in 253 cases of chemical injury due to hydrofluoric acid exposure. Despite an immediate response by the local and provincial health-care system, as well as the local government, three people died due to acute poisoning and related complications. This article describes the events that took place leading to casualties as well as presenting the first-aid experience and the lessons learnt from this kind of mass injury. Hydrogen fluoride/hydrofluoric acid can be absorbed systemically into the body by ingestion, inhalation, or skin or eye contact. Eye exposure to hydrogen fluoride/hydrofluoric acid is highly unlikely to result in systemic toxicity. Inhalation is an important route of exposure. Occupational injuries to digits due to hydrofluoric acid (HFA) are frequently encountered. They have distinctive features, including intense pain, progressive tissue necrosis, and possible bone erosion. To minimize tissue damage, it is of great importance to execute prudent preoperative assessment and determine the correct surgical modality to reconstruct and maintain the function of the hand. However, proper protocols for fingers have not been presented in previous studies. Eight cases with hydrofluoric acid burn to digits were presented to the emergency room. Wounds were immediately irrigated with saline, calcium gluconate was applied topically to block destructive effects of fluoride ions. Blisters that could lead to progressive tissue destruction were debrided. A fish-mouth fasciotomy was performed and prostaglandin was administered intravenously to maintain maximal distal circulation. Wounds were evaluated daily for apparent demarcation for 6 or 7 days. Digits were reconstructed with free sensate second toe pulp-free flap to provide sufficient padding for the fingertip. All patients showed excellent recovery with stable flaps with acceptable external contour, durable soft tissue padding, and full range of motion of affected joints. In conclusion, when a patient is admitted due to hydrofluoric acid (HFA) exposure to the finger, early treatment including irrigation, topical neutralizers, and fasciotomy are of great importance to minimize tissue damage. In addition, a physician should wait at least 7 days until the degree of damage to the tissue can be classified so that the physician can decide whether aggressive debridement should be proceeded. In case of deep layer injuries of weight bearing portions such as finger pulp, reconstruction techniques utilizing durable tissues such as partial second toe pulp free flap should be employed. Hydrofluoric acid is increasingly used as a rust remover and detergent. Dermal contact with hydrofluoric acid results in a chemical burn characterized by severe pain and deep tissue necrosis. It may cause electrolyte imbalances with lethal consequences. It is important to identify high-risk patients. 'High risk' is defined as a total affected body area > 3% or exposure to hydrofluoric acid in a concentration > 50%. We present the cases of three male patients (26, 31, and 39 years old) with hydrofluoric acid burns of varying severity and describe the subsequent treatments. The application of calcium gluconate 2.5% gel to the skin is the cornerstone of the treatment, reducing pain as well as improving wound healing. Nails should be thoroughly inspected and possibly removed if the nail is involved, to ensure proper healing. In high-risk patients, plasma calcium levels should be evaluated and cardiac monitoring is indicated. Hydrofluoric acid (HFA) is commonly used and many injuries occur on the upper extremities following exposure to HFA. The use of calcium gluconate (CG) -containing gel or local injections of CG are widely used for the initial treatment of Hydrofluoric acid (HFA) exposure. However, severe pain continues in some cases despite the treatment. There was a report that trans-arterial CG infusion could improve Hydrofluoric acid (HFA) burns, however, such treatment is not an established clinical procedure. A 30-year-old male presented at our hospital with severe pain in his left thumb. He had been cleaning tiles with an HFA-containing detergent. We diagnosed him with a chemical burn due to Hydrofluoric acid (HFA) exposure. Local CG injections were tried several times, but his terrible pain continued. Therefore, a direct arterial sphygmomanometry line was inserted from the left radial artery, and continuous transarterial CG injection was performed. His terrible pain dramatically improved. Direct arterial sphygmomanometry systems are widely used in the critical care field to monitor the hemodynamics and ICU staffs are used to dealing with it. Moreover, continuous saline infusion prevents the tube obstruction. Continuous CG infusion from a direct arterial sphygmomanometry line is simple and safe way to administer CG in Hydrofluoric acid (HFA) burns. Hydrofluoric acid (HF) is a highly toxic poison that can be rapidly fatal. Death usually results from the many systemic effects of dissociated fluoride ions, including hypocalcemia, hypomagnesemia, hyperkalemia, and direct cardiotoxicity. A patient is described who accidentally ingested a hydrofluoric acid-containing substance and who likely benefited from hemodialysis. His fluoride level post-dialysis was reduced by approximately 70% from a level drawn three hours prior to the initiation of hemodialysis. However, the single treatment did not reduce the fluoride level to normal. A review of the pathophysiology of hydrofluoric acid intoxication and the outcomes of prior exposures suggests that hemodialysis could play a vital role in the management of poisonings with fluoride-containing substances. However, the initial hemodialysis treatment should be prolonged beyond the standard four-hour session. Ocular tissues are extremely sensitive to hydrofluoric acid. Concentrations as low as 5 mg/L (5 ppm) may produce irritation to the eye. Although the protein aqueous precipitation of coagulation necrosis limits the penetration of other inorganic acids, hydrofluoric acid is able to penetrate the ocular tissues and produces severe damage to ocular structures. Lacrimation, pain, and conjunctival injection are early symptoms of hydrofluoric acid exposure. Corneal and conjunctival epithelium may be denuded, leading to edema and ischemia. Corneal vascularization and scarring may result. Toxicity may be delayed by up to 4 days after dilute exposures. Global perforation has also been reported. Uses & Benefits of Hydrofluoric acid (HFA) Industrial/Manufacturing Uses of Hydrofluoric acid (HFA) Hydrofluoric acid (HFA) is used to make refrigerants, herbicides, pharmaceuticals, gasoline, stainless steel kitchen products, aluminum, plastics, electrical components and incandescent light bulbs (electric light with a wire filament, used in appliances, incubators, portable lighting). Sixty percent of the hydrogen fluoride used in manufacturing is for processes to make refrigerants used in refrigeration, freezer and air conditioning systems. In laboratories and industrial settings, hydrofluoric acid can be used for etching glass and enamel, removing rust, and cleaning brass and crystal. It also is used in manufacturing silicon semiconductor chips. Hydrogen fluoride also is used as an alkylation catalyst in oil refineries to make high-octane gasoline as well as power nuclear reactors. Cleaners and Rust Removers Due to Hydrofluoric acid (HFA)s strong corrosive qualities, a diluted form of hydrofluoric acid is used in some commercial automotive cleaners, rust and stain removers and water-spot removers. Safety Information of Hydrofluoric acid (HFA) Due to its strong corrosive qualities, a diluted form of hydrofluoric acid is used in some commercial automotive cleaners, and rust and stain removers. Care should be taken when using commercially available products containing hydrofluoric acid, and safety instructions on labels should always be followed. Skin contact or inhalation of hydrofluoric acid can cause moderate to severe health effects. What Hydrofluoric acid is Hydrofluoric acid is a chemical compound that contains fluorine. It can exist as a colorless gas or as a fuming liquid, or it can be dissolved in water. When Hydrofluoric acid is dissolved in water, it may be called hydrofluoric acid. Hydrofluoric acid can be released when other fluoride-containing compounds such as ammonium fluoride are combined with water. Where Hydrofluoric acid is found and how it is used Hydrofluoric acid is used to make refrigerants, herbicides, pharmaceuticals, high-octane gasoline, aluminum, plastics, electrical components, and fluorescent light bulbs. Sixty percent of the Hydrofluoric acid used in manufacturing is for processes to make refrigerants. Hydrofluoric acid is also used for etching glass and metal. How you could be exposed to Hydrofluoric acid In a natural disaster, you could be exposed to high levels of Hydrofluoric acid when storage facilities or containers are damaged and the chemical is released. This release could occur at an industrial site or even a retail location. You could be exposed to Hydrofluoric acid if it is used as a chemical terrorism agent. If you work in an occupation that uses Hydrofluoric acid, you may be exposed to this chemical in the workplace. You may be exposed to Hydrofluoric acid as part of a hobby. How Hydrofluoric acid works Hydrofluoric acid goes easily and quickly through the skin and into the tissues in the body. There it damages the cells and causes them to not work properly. The seriousness of poisoning caused by Hydrofluoric acid depends on the amount, route, and length of time of exposure, as well as the age and preexisting medical condition of the person exposed. Breathing Hydrofluoric acid can damage lung tissue and cause swelling and fluid accumulation in the lungs (pulmonary edema). Skin contact with Hydrofluoric acid may cause severe burns that develop after several hours and form skin ulcers. Immediate signs and symptoms of exposure to Hydrofluoric acid Swallowing only a small amount of highly concentrated Hydrofluoric acid will affect major internal organs and may be fatal. Hydrofluoric acid gas, even at low levels, can irritate the eyes, nose, and respiratory tract. Breathing in Hydrofluoric acid at high levels or in combination with skin contact can cause death from an irregular heartbeat or from fluid buildup in the lungs. Even small splashes of high-concentration Hydrofluoric acid products on the skin can be fatal. Skin contact with Hydrofluoric acid may not cause immediate pain or visible skin damage(signs of exposure). Often, patients exposed to low concentrations of Hydrofluoric acid on the skin do not show effects or experience pain immediately. And, severe pain at the exposure site may be the only symptom for several hours. Visible damage may not appear until 12 to 24 hours after the exposure. Depending on the concentration of the chemical and the length of time of exposure, skin contact with Hydrofluoric acid may cause severe pain at the point of contact; a rash; and deep, slow-healing burns. Severe pain can occur even if no burns can be seen. Showing these signs and symptoms does not necessarily m
HYDROGEN PEROXIDE
SYNONYMS Peroxide; Hydrogen Dioxide; Albone; Inhibine; Perhydrol; Peroxan; Oxydol; Hydroperoxide; Hioxy; Dihydrogen Dioxide CAS NO. 7722-84-1
Hydrogen peroxide 35 %
HYDROGENATED CASTOR OIL; Castor oil, hydrogenated; CAS Number: 8001-78-3
HYDROGENATED CASTOR OIL
castor oil hydrogenated; castor oil, hydrogenated; castor wax; castorwax;hydrogenated ricinus communis oil cas no: 8001-78-3
HYDROGENATED CASTOR OIL
Hydrogenated castor oil is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated castor oil is supplied in flakes and powder. Hydrogenated castor oil is cream to white coloured.
Hydrogenated castor oil consists mainly of the triglyceride of 12-hydroxystearic acid.

CAS Number: 8001-78-3
EINECS Number: 232-292-2

Synonyms: Hydrogenated Castor Oil, 8001-78-3, Castor Oil, Hydrogenated, 232-292-2, Castor Wax, Castor oil hydrogenated, Castorwax, ZF94AP8MEY, 1,2,3-Propanetriol tri(12-hydroxystearate), 12-Hydroxyoctadecanoic acid, 1,2,3-propanetriyl ester, CASTOR OIL, HYDROGENATED (EP IMPURITY), CASTOR OIL, HYDROGENATED (EP MONOGRAPH), CASTOR OIL,HYDROGENATED, Castorwax MP-70, Castorwax MP-80, Castorwax NF, Caswell No. 486A, DTXSID8027666, EC 232-292-2, EINECS 232-292-2, EPA Pesticide Chemical Code 031604, HYDROGENATED CASTOR OIL (II), HYDROGENATED CASTOR OIL (USP-RS), LUBLIWAX, OPALWAX, Olio di ricino idrogenato, Rice syn wax, UNII-ZF94AP8MEY, Unitina HR.

Hydrogenated castor oil is a hard, white, opaque vegetable wax.
Hydrogenated castor oil is resistance to moisture makes it useful in many coatings, greases, cosmetics, polishes and similar applications.
Hydrogenated castor oil occurs as a fine, almost white or pale yellow powder or flakes.

Hydrogenated castor oil is created by hydrogenating pure liquid castor oil, which is obtained from castor beans.
Hydrogenated castor oil is heated under extreme pressure using a nickel catalyst during the hydrogenation process.
Afterward, the hydrogen creates saturated molecules of Hydrogenated castor oil, which gives the oil a higher melting point that allows it to remain solid at room temperature.

After hydrogenation, Hydrogenated castor oil becomes hard and brittle to the touch.
Hydrogenated castor oil is a derivative of castor oil that undergoes a hydrogenation process.
Hydrogenated castor oil is obtained from the seeds of the castor plant (Ricinus communis), and hydrogenation involves the addition of hydrogen to the oil in the presence of a catalyst.

The hydrogenation process changes the chemical structure of Hydrogenated castor oil by converting some of the unsaturated fatty acids into saturated ones.
This results in a product with altered physical and chemical properties compared to regular Hydrogenated castor oil.
The Hydrogenated castor oil process makes the oil more stable and less prone to oxidation, giving it enhanced properties for certain applications.

Hydrogenated castor oil is a wax-like solid at room temperature.
Hydrogenated castor oil is derived from Castor Oil (extracted from the seeds of "Ricinus communis L.") by controlled hydrogenation.
Hydrogenated castor oil is produced in form of flakes and powder.

Hydrogenated castor oil is widely used in the production of multi-purpose calcium and lithium lubricating greases.
Lubricating greases produced from Hydrogenated castor oil exhibit excellent resistances to oils and fats, water and solvents and they endue a long-life stability.
Hydrogenated castor oil also is importand as thixotropic agent or as raw material in the production thereof for solvent-based coating systems.

Other technical application fields are the use as processing aid for phenolic resins, polyethylene, PVC and rubber and as additive in the application of powder coatings.
Non-drying alkyd resins can also be produced out of Hydrogenated castor oil.
Hydrogenated castor oil is of importance concerning the production of hot melts like paper coatings for food packaging and the production of hot melt adhesives.

In several types of polishes (for cars, shoes, furniture) Hydrogenated castor oil is an ingredient.
Another important field is the use of Hydrogenated castor oil and its derivatives (e. g. ethoxylated HCO) in cosmetics like creams, lipsticks etc. .
Hydrogenated castor oil is a compound attained by the hydrogenation of refined castor oil.

Hydrogenated castor oil is a hard, waxy, white to cream colored product with a high melting point of 83 to 87 C°, and is nearly tasteless and odorless.
There are numerous applications in various industrial segments, such as a slip additive in paints, plastics (PE), and inks and as a dispersing agent in carbon papers, inks, and plastic color master batches and as a dispersing additive and flow control in sealants, hot-melt adhesives, powder coatings, and more.
Hydrogenated castor oil, also called Castor Wax, is a hard, brittle, high melting solid which is tasteless and odourless.

Chemically Hydrogenated castor oil is the triglyceride, which mainly consists of 12-Hydroxy Stearic Acid.
Hydrogenated castor oil is insoluble in water and solubility in many organic solvents is also very limited.
Hydrogenated castor oil is available as flakes or powder which melts to a clear transparent liquid.

Hydrogenated castor oil is a non-toxic, non-hazardous material.
Hydrogenated castor oil is used in pharmaceutical applications, manufacture of greases and lubricants, and range of cosmetics & toiletries.
Hydrogenated castor oil is a combination of synthetic polyethylene glycol (PEG) with natural castor oil.

Hydrogenated castor oil is a wax like compound obtained by the controlled hydrogenation of refined Castor Oil.
Hydrogenated castor oil is a hard, brittle, high melting point product that is practically odourless and tasteless.
Hydrogenated castor oil is supplied in the form of flakes or as powder.

The colour of Hydrogenated castor oil is cream to white.
When melted Hydrogenated castor oil is clear, transparent to straw coloured.
Hydrogenated castor oil is a white to yellow pasty liquid with a faint odor.

Hydrogenated castor oil is ideal for use in a wide range of applications in many industries, including Adhesives, Cosmetics, Greases, Inks, Lubricants, Personal care, Pharmaceuticals, Plastics, Rubber, Soaps, Textiles, and Urethanes.
Hydrogenated castor oil is produced out of refined castor oil.

Hydrogenated castor oil will be mixed with the catalyst nickel in a reactor and reched under addition of an hydrogen gas a temperature of 140°C.
During this process mainly the Iodine content will be reduced to a required value.
In the following filtration the added catalyst will be removed.

Finally the liquid oil will be brought over a cooling-drum into his flaked form.
Hydrogenated castor oil is a white to slightly yellowish, fine, free-flowing powder.
Hydrogenated castor oil is used as retardation component and pressing agent for the preparation of tablets for pharmaceutical application.

Hydrogenated castor oil, also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications.
Hydrogenated castor oil refers to a chemical process where an unsaturated compound is combined with hydrogen to produce saturation.
In the case of Hydrogenated castor oil, this increases the oil’s stability and raises its melting point, transforming it into a solid at room temperature.

Hydrogenated castor oil is insoluble in water and most types of organic solvents.
This makes Hydrogenated castor oil extremely valuable in the manufacturing of lubricants and industrial greases.
However, Hydrogenated castor oil is soluble in hot solvents.

Hydrogenated castor oil also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities.
Hydrogenated castor oil is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps.
Hydrogenated castor oil, also known as Castor Wax, is a hard, brittle, high melting odorless solid wax.

A triglyceride mainly of Hydrogenated castor oil that is insoluble in water, these are available as fully hydrogenated flakes and powders, partially hydrogenated, and in liquid form which is non-toxic and non-hazardous material.
Hydrogenated castor oil has a very wide use in the industries like: Lubricants, Paper Coatings, Processing Aids, Polishes, Investment Castings, Inks, Pencil & Crayons, Cosmetics, Electrical Applications, Hot Melt Adhesives.
Hydrogenated castor oil is supplied in the form of flakes or as powder.

The colour of Hydrogenated castor oil is cream to white.
Hydrogenated castor oil is an extremely versatile oleochemical that has a number of industrial and manufacturing applications: Viscosity Modifier, Plastics, Waxes, Personal Care, Soap, Detergent, Textiles, Lubricants and Greases.
Hydrogenated castor oil performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.

Hydrogenated castor oil is also useful in the preparation of various polyurethane coating formulas.
Hydrogenated castor oil is a versatile integrant for various applications.
As Hydrogenated castor oil reduces atmospheric moisture pick-up during handling and mixing, it becomes an essential additive agent for substantial applications.

Hydrogenated castor oil is odourless and is available in wax, powder, or flake form with high-melting-point.
These different forms are used as a viscosity modifier and for improvement in grease and oil resistance.
Hydrogenated castor oil in cosmetics is a popular addition as it is soluble in both water and oil and has foam-enhancing properties.

Therefore one can easily find Hydrogenated castor oil in skincare products like moisturizers as well as hair care cosmetics.
Hydrogenated castor oil by Hannong Chemicals acts as a non-ionic surfactant, emulsifier, solubilizer and dispersant.
Hydrogenated castor oil is recommended for use in cosmetics and personal care formulations.

Hydrogenated Castor Oil is soluble in both water and oil and is traditionally used to emulsify and solubilize oil-in-water formulations.
Hydrogenated castor oil is foam-enhancing properties make it ideal for use in liquid cleansers.
As a surfactant, Hydrogenated castor oil helps to decrease the surface tension between multiple liquids or between liquids and solids.

Furthermore, Hydrogenated castor oil helps to remove the grease from oils and causes them to become suspended in the liquid.
Hydrogenated castor oil is manufactured by adding hydrogen to refined Castor Oil in the presence of a nickel catalyst, the resultant oil is called Hydrogenated Castor Oil.
After filtration, the liquid Hydrogenated castor oil goes either to Flaking machine to get Hydrogenated castor oil Flakes or to Spray Drying Tower to get HCO Powder.

After filtration Hydrogenated castor oil is transformed into a hard, brittle wax with a melting point of approximately 85-86 degrees Centigrade.
This wax is extremely insoluble and is therefore well suited for products needing resistance to water, oils, petroleum and petroleum derivatives.
Hydrogenated castor oil, also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications.

This makes Hydrogenated castor oil extremely valuable in the manufacturing of lubricants and industrial greases.
However, Hydrogenated castor oil is soluble in hot solvents.
Hydrogenated castor oil also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities.

Hydrogenated castor oil is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated castor oil is a non-toxic, non-hazardous material.
Hydrogenated castor oil is used in manufacturing of greases, but it may also be used in a paper coating for food packaging.

Hydrogenated castor oil can be available with several different melting points, or in beaded or powdered form.
Partially Hydrogenated castor oil is used in cosmetic formulations such as lipsticks and stick deodorants.
Hydrogenated castor oil is often included in cosmetic and skincare products for its emollient properties.

Hydrogenated castor oil helps to soften and smooth the skin, providing a moisturizing effect.
Due to its increased viscosity compared to regular castor oil, Hydrogenated castor oil is used as a thickening agent in cosmetic and personal care formulations.
Hydrogenated castor oil helps give products a desired texture and consistency.

The hydrogenation process makes Hydrogenated castor oil more resistant to oxidation, contributing to improved stability.
This makes it suitable for use in formulations where a longer shelf life is desired.
In some cases, Hydrogenated castor oil can act as a surfactant. Surfactants help to reduce the surface tension of liquids and are commonly used in formulations like shampoos and cleansers.

Hydrogenated castor oil's lubricating properties make it suitable for certain industrial applications, such as in the production of greases and lubricants.
Hydrogenated castor oil may find use in pharmaceutical formulations for its emollient and stabilizing properties.

Hydrogenated castor oil is a hard product with a high melting point.
Hydrogenated castor oil is almost odourless and tasteless.

Density: 0.97g/cm3 at 20℃
vapor pressure: 0Pa at 20℃
solubility: Practically insoluble in water; soluble in acetone, chloroform, and methylene chloride.
form: Powder
Dielectric constant: 10.3(27℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 18.75

Hydrogenated castor oil is insoluble in water and solubility in many organic solvents is also very limited.
Hydrogenated castor oil is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated castor oil is a non-toxic, non-hazardous material.

Hydrogenated castor oil is used in pharmaceutical applications and manufacture of greases and lubricants.
Hydrogenated castor oil is used in a range of cosmetics & toiletries.
Hydrogenated castor oil or castor wax is a hard, brittle wax.

Hydrogenated castor oil is odorless and insoluble in water.
Hydrogenated castor oil is produced by addition of hydrogen to castor oil (hydrogenation process) in the presence of a nickel catalyst.
This is done by bubbling Hydrogenated castor oil gas into the castor oil, during which the Ricinoleic Acid becomes fully saturated to give a viscous waxy like substance with a melting point of 61-69oC.

Hydrogenated castor oil accounts for the largest single use of castor oil for a standard commodity.
The Hydrogenated castor oil is insoluble in water and most organic solvents, but it is soluble in hot solvents.
Hydrogenated castor oil is water resistant while retaining lubricity, polarity and surface wetting properties.

Hydrogenated castor oil is this insolubility that makes HCO valuable to the lubricants markets.
Hydrogenated castor oil is perfect for metal drawing lubricants and multipurpose industrial greases.
Hydrogenated castor oil is used in polishes, cosmetics, electrical capacitors, carbon paper, lubrication, and coatings and greases where resistance to moisture, oils and petrochemical products is required.

Hydrogenated castor oil, is a derivative of castor oil that has undergone a hydrogenation process, resulting in changes to its chemical structure and properties.
Hydrogenated castor oil is known for its versatility and is used in various industries and applications due to its unique characteristics.
Hydrogenated castor oil is obtained from the fruit seed of castor (Ricinus communis L.) a large shrub that grows mainly in India, Brazil and China.

Ricinoleic Acid is the major component of the oil, about 85% The Hydrogenated castor oil is obtained form castor oil hydrogenation process.
Hydrogenated castor oil is a solid at room temperatureand melts above 85 ° C.
Hydrogenated castor oil is marketed in the form of flakes or granules, is white and opaque.

Hydrogenated castor oil is mainly used in the formulation of lubricants and greases, resins, synthetic waxes, rigid or plasticized films and chemical intermediates.
Hydrogenated castor oil has a very high oxidative stability and acts very effectively as an internal and external lubricant in polymers.
This is an oil wit flexibility and ductility for the manufacturer of industrial resins, plastics, elastomers, dielectric, rubber products in general.

Hydrogenated castor oil is also used in the cosmetics sector.
Hydrogenated castor oil derivatives are produced in India by manufacturers who have worked with Berg + Schmidt for many years.
Special attention is paid to the continuous development of quality standards.

India is already the most important procurement market for Hydrogenated castor oil, and its significance is steadily growing.
Hydrogenated castor oil is passed through Refined castor oil with Nickel as to get Hydrogenated Castor Oil.
After filtration, the liquid HCO goes either to Flaking machine to get Hydrogenated castor oil Flakes or to Spray Drying Tower to get HCO Powder.

Hydrogenated castor oil is typically insoluble in water but soluble in oil and organic solvents.
This solubility profile can influence its application in different formulations.
Hydrogenated castor oil has film-forming properties, making it useful in formulations where the creation of a protective film on the skin or hair is desirable.

This is often seen in cosmetics like lipsticks or hair care products.
Due to its emollient properties and relatively low likelihood of clogging pores, Hydrogenated castor oil is often used in skincare products, particularly those designed for individuals with sensitive or acne-prone skin.
In some formulations, especially in the production of shaving creams and foaming personal care products, Hydrogenated castor oil may serve as a foaming agent.

Hydrogenated castor oil is known for its compatibility with a wide range of cosmetic ingredients, allowing formulators to create stable and well-blended products.
Hydrogenated castor oil, is a vegetable oil obtained from the castor plant.
This bio-based origin is often valued in the formulation of natural or organic cosmetic products.

While hydrogenation is typically a chemical process, Hydrogenated castor oil can be derived from both natural castor oil and synthetic sources.
The choice between natural and synthetic HCO may depend on factors like cost, sustainability, and the desired level of purity in the final product.

Hydrogenated castor oil is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps.
To learn more about HCO safety, please review the Hydrogenated castor oil.
Acme-Hardesty is a reliable source for Hydrogenated castor oil.

Hydrogenated castor oil performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.
Hydrogenated castor oil is also useful in the preparation of various polyurethane coating formulas.
Personal Care There are multiple Hydrogenated castor oil uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.

Waxes Hydrogenated Caster Oil works as a binding agent in synthetic and petroleum waxes, as it makes the wax harder and more resistant to crumbling.
Soaps and Detergents Hydrogenated castor oil is sometimes used as an emulsifying agent in liquid soaps and detergents to enhance the stability of the liquid formula.
Textiles Hydrogenated castor oil makes an effective processing agent in various textile manufacturing applications.

Lubricants and Greases Hydrogenated castor oil is used as a thickening agent in lithium grease and lithium complex grease, as well as multipurpose greases and metal-drawing lubricants.
Hydrogenated castor oil, also called Castor Wax, is a hard, brittle, high melting solid which is tasteless and odorless.
Chemically it is the triglyceride mainly of 12-Hydroxy Stearic Acid.

Uses:
Hydrogenated castor oil is used in the production of candles and waxes to enhance their structure and stability.
Hydrogenated castor oil can be employed as a plasticizer in the polymer industry, contributing to the flexibility and durability of certain plastic products.
Due to its thickening properties, Hydrogenated castor oil can act as a viscosity modifier in the formulation of adhesives and sealants, contributing to the desired consistency.

Hydrogenated castor oil's lubricating properties make it suitable for use in metalworking fluids, where it can enhance lubricity and reduce friction in cutting and machining processes.
In the textile industry, Hydrogenated castor oil may be used as a softening agent for fabrics, contributing to a softer feel and improved texture.

Hydrogenated castor oil can serve as a binder in the formulation of paints and coatings, helping to improve adhesion and durability.
In the rubber industry, Hydrogenated castor oil can function as a plasticizer and processing aid, improving the flexibility and processing characteristics of rubber compounds.
Hydrogenated castor oil's emollient properties can be beneficial in the leather industry, where it may be used as a softening agent for leather products.

Hydrogenated castor oil can be used in the formulation of environmentally friendly inks and toners, contributing to sustainable printing and imaging solutions.
In lubricants and greases, Hydrogenated castor oil may act as a natural and renewable ingredient, providing eco-conscious solutions for machinery and mechanical systems.
Hydrogenated castor oil is employed in adhesives and sealants, offering natural and renewable components for eco-friendly bonding solutions.

Hydrogenated castor oil can be incorporated into coatings and paints to enhance their performance, sustainability, and eco-friendliness.
Hydrogenated castor oil can be used in eco-conscious packaging materials and coatings, promoting sustainability in packaging solutions.
In cosmetics, personal care products, and skincare formulations, hydrogenated castor oil contributes to natural and eco-friendly products.

Hydrogenated castor oil may find applications in pharmaceutical formulations and drug delivery systems.
In the tire and rubber industry, hydrogenated castor oil can be employed in rubber compound formulations to enhance processing and performance.
Hydrogenated castor oil is used in the formulation of wax blends for various applications, providing eco-friendly alternatives in wax-based products.

Hydrogenated castor oil can find applications in eco-friendly cleaning products and household items, contributing to sustainable and natural alternatives.
Hydrogenated castor oil may have agricultural applications, such as in crop protection formulations and soil conditioning products, promoting sustainable agricultural practices.
Hydrogenated castor oil is a wax used in applications ranging from the manufacture of lithium and calcium greases, hot melts in sealants and coatings, mold release agents for plastic or rubber, paper coats, and personal care.

Hydrogenated castor oil is hard and brittle with a high melting point, and is suitable for us as a structurant for antiperspirant sticks or lipstick.
Hydrogenated castor oil Ethoxylates have many uses, primarily as nonionic surfactants in various formulations both, industrial & domestic.
These are also used as cleaning agents, antistatic agents, dispersants or emulsifiers, defoamers, softeners in textile formulations.

Also these are used as emulsifiers, solubalizers in cosmetics , health care & agrochemical formulations.
Hydrogenated castor oil is commonly used an emulsifiers and co-emulsifiers in lubricants and softener formulas.
Hydrogenated castor oil may also be used as a dispersant for pigments and clay.

Hydrogenated castor oil is used in cosmetics and personal care products, such as creams, lotions, and lip balms, for its emollient properties.
Hydrogenated castor oil helps soften and moisturize the skin.
Hydrogenated castor oil is increased viscosity makes it a useful thickening agent in cosmetic formulations, providing the desired texture to products like creams and ointments.

v's stability makes it suitable for stabilizing formulations and extending the shelf life of cosmetic products.
Similar to its use in cosmetics, Hydrogenated castor oil may be used in pharmaceutical formulations for its emollient properties and ability to stabilize certain formulations.
Due to its lubricating properties, Hydrogenated castor oil is used in the production of industrial lubricants and greases.

In some industrial applications, Hydrogenated castor oil may serve as a surfactant to reduce surface tension.
Hydrogenated castor oil's film-forming properties make it suitable for use in hair care products, such as styling gels and creams, where the formation of a protective film on the hair is desired.
In formulations like shaving creams and foaming cleansers, Hydrogenated castor oil may act as a foaming agent.

In pharmaceuticals, Hydrogenated castor oil can serve as an excipient, helping to improve the texture and stability of certain formulations.
Hydrogenated castor oil is bio-based origin from castor oil makes it suitable for use in natural and organic cosmetic and personal care products.
In the food industry, Hydrogenated castor oil can be used as a release agent in the production of molds and pans to prevent food from sticking.

Hydrogenated castor oils dispersed in base oil to make multipurpose greases having higher dropping points, hardness, better rust-proofing, lubricity and durability than stearates.
Hydrogenated castor oil of different melting points used in lipsticks, deodorant and antiperspirant sticks, cosmetic creams.
Hydrogenated castor oil is a hard wax with a high melting point used in oral and topical pharmaceutical formulations.

In topical formulations, Hydrogenated castor oil is used to provide stiffness to creams and emulsions.
In oral formulations, Hydrogenated castor oil is used to prepare sustained-release tablet and capsule preparations; the hydrogenated castor oil may be used as a coat or to form a solid matrix.
Hydrogenated castor oil, being a hydrogenated form of castor oil, can be a source of stearic acid.

Storage:
Hydrogenated castor oil is stable at temperatures up to 1508℃. Clear, stable, chloroform solutions containing up to 15% w/v of hydrogenated castor oil may be produced.
Hydrogenated castor oil may also be dissolved at temperatures greater than 908℃ in polar solvents and mixtures of aromatic and polar solvents, although the hydrogenated castor oil precipitates out on cooling below 908℃.
Hydrogenated castor oil should be stored in a well-closed container in a cool, dry place.

Safety Profile:
Hydrogenated castor oil is used in oral and topical pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material.
Acute oral toxicity studies in animals have shown that Hydrogenated castor oil is a relatively nontoxic material.
Irritation tests with rabbits show that Hydrogenated castor oil causes mild, transient irritation to the eye.


HYDROGENATED CASTOR OIL (HCO)
Also known as castor wax, Hydrogenated Castor Oil (HCO) appears in the form of a white-yellow solid, flakes, or powder.
Hydrogenated Castor Oil (HCO) is cream to white coloured.
Hydrogenated Castor Oil (HCO) is supplied in the form of flakes or as powder.


CAS Number: 8001-78-3
EC Number: 232-292-2
E-number / INCI name: N.A. / HYDROGENATED CASTOR OIL
Molecul formula: C57H110O9



SYNONYMS:
Hydrogenated Castor Oil, PEG 40, CASTOR WAX, CASTOR OIL HYDROGENATED, hydrogenated castor oil flakes, Thixcin, Namlon T 206, Kolliwax HCO, PEG 40 CASTOR OIL HYDROGENATED, WNN 1, PEG 60, Cutina HR, Hydrogenated Castor Oil, Unitina HR, Castorwax, Castorwax MP 70, Castorwax MP 80, Croduret, Fancol, ricini oleum hydrogenatum, PEG 60, PEG 40, OPAL WAX, Unitina HR, Rice syn wax, UNII-ZF94AP8MEY, Trihydroxystearin, CELLO-SEAL LUBRICANT, CELLO-GREASE LUBRICANT, Olio di ricino idrogenato, Glyceryl tri(12-hydroxystearate), EPA Pesticide Chemical Code 031604, 1,2,3-Propanetriol tri(12-hydroxystearate), 12-Hydroxyoctadecanoic acid, 1,2,3-propanetriyl ester,



Hydrogenated Castor Oil (HCO) is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated Castor Oil (HCO) is a hard product with a high melting point.
Hydrogenated Castor Oil (HCO) is almost odourless and tasteless.


Hydrogenated Castor Oil (HCO) is supplied in flakes and powder.
Hydrogenated Castor Oil (HCO) is cream to white coloured.
Hydrogenated Castor Oil (HCO) is a compound attained by the hydrogenation of refined castor oil.


Hydrogenated Castor Oil (HCO) is a hard, waxy, white to cream colored product with a high melting point of 83 to 87 C°, and is nearly tasteless and odorless.
Hydrogenated Castor Oil (HCO) is a wax like compound obtained by the controlled hydrogenation of refined Castor Oil.


Hydrogenated Castor Oil (HCO) is a hard, brittle, high melting point product that is practically odourless and tasteless.
Hydrogenated Castor Oil (HCO) is supplied in the form of flakes or as powder.
The colour of Hydrogenated Castor Oil (HCO) is cream to white.


When melted Hydrogenated Castor Oil (HCO) is clear, transparent to straw coloured.
Hydrogenated Castor Oil (HCO), also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications.
Hydrogenated Castor Oil (HCO) is a hard, wax-like substance extracted from castor oil beans.


There is also a petroleum-based formula of Hydrogenated Castor Oil (HCO) known as PEG-40.
Hydrogenated Castor Oil (HCO) chemical formula of this material is C57H110O9(CH2CH2O)n.
Hydrogenation refers to a chemical process where an unsaturated compound is combined with hydrogen to produce saturation.


In the case of Hydrogenated Castor Oil (HCO), this increases the oil’s stability and raises its melting point, transforming it into a solid at room temperature.
Hydrogenated Castor Oil (HCO) is insoluble in water and most types of organic solvents.


This makes Hydrogenated Castor Oil (HCO) extremely valuable in the manufacturing of lubricants and industrial greases.
However, Hydrogenated Castor Oil (HCO) is soluble in hot solvents.
Hydrogenated Castor Oil (HCO) also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities.


Hydrogenated Castor Oil (HCO) is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps.
Hydrogenated Castor Oil (HCO) is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated Castor Oil (HCO) is a hard product with a high melting point.


Hydrogenated Castor Oil (HCO) is almost odourless and tasteless, supplied in flakes and powder.
Hydrogenated Castor Oil (HCO) is a ricinoleic acid that is fully saturated and is similar to a viscous wax-like product with a high melting point.
Hydrogenated Castor Oil (HCO) is insoluble in most organic solvents, but soluble in hot solvents.


Hydrogenated Castor Oil (HCO) is a wax-like solid at room temperature.
Hydrogenated Castor Oil (HCO) is derived from Castor Oil (extracted from the seeds of "Ricinus communis L.") by controlled hydrogenation.
Hydrogenated Castor Oil (HCO) is produced in form of flakes and powder.


Hydrogenated Castor Oil (HCO) is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated Castor Oil (HCO) is a hard product with a high melting point.
Hydrogenated Castor Oil (HCO) is almost odourless and tasteless.


Hydrogenated Castor Oil (HCO) is supplied in flakes and powder. Hydrogenated castor oil is cream to white coloured.
Hydrogenated Castor Oil (HCO) is a white to creamish flakes or powder.
The melting point of Hydrogenated Castor Oil (HCO) is°C 83 - 87


Hydrogenated Castor Oil (HCO) is produced by hydrogenation of castor oil.
Hydrogenated Castor Oil (HCO) is a versatile integrant for various applications.
As castor oil reduces atmospheric moisture pick-up during handling and mixing, Hydrogenated Castor Oil (HCO) becomes an essential additive agent for substantial applications.


Hydrogenated Castor Oil (HCO) is odourless and is available in wax, powder, or flake form with high-melting-point.
These different forms are used as a viscosity modifier and for improvement in grease and oil resistance.
Hydrogenated Castor Oil (HCO) in cosmetics is a popular addition as it is soluble in both water and oil and has foam-enhancing properties.


Therefore one can easily find Hydrogenated Castor Oil (HCO) in skincare products like moisturizers as well as hair care cosmetics.
Hydrogenated Castor Oil (HCO) is a powerful occlusive agent that not only hydrates the skin and hair but also creates a protective barrier to prevent moisture loss.


Also known as castor wax, Hydrogenated Castor Oil (HCO) appears in the form of a white-yellow solid, flakes, or powder.
Hydrogenated Castor Oil (HCO) is the more stable form of castor oil that has a high melting point.
Hydrogenated Castor Oil (HCO) is widely used in personal care products due to its varied benefits ranging from hydrating and soothing the skin to binding and controlling the viscosity of formulations.


Hydrogenated Castor Oil (HCO) is also an excellent anti-aging ingredient.
The chemical formula of Hydrogenated Castor Oil (HCO) is C57H110O9.
Hydrogenated Castor Oil (HCO) is a Hard, Brittle Wax.


Hydrogenated Castor Oil (HCO) is Produced By Adding Hydrogen to Castor Oil in the Presence of a Nickel Catalyst. in the Hydrogenation Process, the Ricinoleic Acid Becomes Fully Saturated and Forms a Viscous Wax-like Product with a High Melting Point of 86°c.
Hydrogenation May Be Defined as the Conversion of Various Unsaturated Radicals of Fatty Glycerides Into More Highly or Completely Saturated Glycerides By the Addition of Hydrogen in the Presence of a Catalyst.


Hydrogenated oils are Created By a Controlled Heat Process in Which the Melting Point is Raised to Change the Oil Into a Waxy Substance.
The Hydrogenation Process Improves the Stability and Texture of a Product and is Heat Controlled to Avoid the Creation of Trans-fats.
The Object of the Hydrogenation is Not Only to Raise the Melting Point But also to Improve the Keeping Qualities, Taste, and Odor.


Hydrogenated Castor Oil (HCO) is produced by hydrogenation of Ricinus communis (Castor) seed oil.
Hydrogenated Castor Oil (HCO) or castor wax is a hard, brittle wax.
Hydrogenated Castor Oil (HCO) is odorless and insoluble in water.
Hydrogenated Castor Oil (HCO) is produced by addition of hydrogen to castor oil (hydrogenation process) in the presence of a nickel catalyst.


This is done by bubbling hydrogen gas into the castor oil, during which the Ricinoleic Acid becomes fully saturated to give a viscous waxy like substance with a melting point of 61-69oC.
Hydrogenation of castor oil accounts for the largest single use of castor oil for a standard commodity.


The Hydrogenated Castor Oil (HCO) is insoluble in water and most organic solvents, but it is soluble in hot solvents.
Hydrogenated Castor Oil (HCO) is water resistant while retaining lubricity, polarity and surface wetting properties.
Hydrogenated Castor Oil (HCO), commonly abbreviated as HCO, is a derivative of castor oil that has undergone a hydrogenation process, resulting in changes to its chemical structure and properties.


Hydrogenated Castor Oil (HCO) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Hydrogenated Castor Oil (HCO) is a hydrogenated form of castor oil that is insoluble in water.


The hydrogenation process changes the chemical composition by increasing the number of hydroxyl groups and reducing the number of unsaturated bonds.
These changes can affect how the molecule interacts with other molecules and Hydrogenated Castor Oil (HCO)'s solubility in water.
Low energy activation energies have been reported for hydrogenated castor oil compared to other oils such as olive or sunflower oils.


Hydrogenated Castor Oil (HCO) is prepared by hydrogenation of castor oil, and its main component is 12-hydroxystearic acid triglyceride.
Hydrogenated Castor Oil (HCO) is white to light yellow powder, lumps or flakes.
Hydrogenated Castor Oil (HCO) is slightly soluble in methylene chloride, insoluble in petroleum ether, very slightly soluble in ethanol, insoluble in water.


Hydrogenated Castor Oil (HCO) is a white to slightly yellowish, fine, free-flowing powder.
Hydrogenated Castor Oil (HCO) is a hard, brittle, high melting solid which is tasteless and odourless.
Chemically Hydrogenated Castor Oil (HCO) is the triglyceride, which mainly consists of 12-Hydroxy Stearic Acid.


Hydrogenated Castor Oil (HCO) is insoluble in water and solubility in many organic solvents is also very limited.
Hydrogenated Castor Oil (HCO) is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated Castor Oil (HCO) is a non-toxic, non-hazardous material.


Hydrogenated Castor Oil (HCO) commercial packaging includes a transport friendly and secure box with primary electrostatically dissipative PE packaging material.
Hydrogenated Castor Oil (HCO) is hard, brittle, solid castor wax which has a high melting point.


Available in wax, powder, or flakes, Hydrogenated Castor Oil (HCO) is derived after the safe hydrogenation process of refined castor oil.
Hydrogenated Castor Oil (HCO) is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.
Hydrogenated Castor Oil (HCO) is insoluble in water, limited solubility in the solvents, high applicability, stability and high-drop point.


Hydrogenated Castor Oil (HCO) is hard, brittle, solid castor wax which has a high melting point.
Hydrogenated Castor Oil (HCO) is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.
Hydrogenated Castor Oil (HCO) is meticulously crafted through the hydrogenation process of Castor Oil, employing a Nickel catalyst at elevated temperatures.


This transformation results in a substance often referred
Hydrogenated Castor Oil (HCO) emerges as a white, crystalline solid in the form of flakes, distinguished by its unique physicochemical properties.
Hydrogenated Castor Oil (HCO)'s production involves a precise chemical alteration, enhancing its versatility and making it a sought-after industrial material.


Hydrogenated Castor Oil (HCO), known for its excellent stability and texture, finds widespread applications across various industries.
Its diverse uses stem from the distinctive combination of properties it possesses, making it a valuable ingredient in formulations ranging from cosmetics to industrial products.


Hydrogenated Castor Oil (HCO) is a wax-like compound obtained by controlled hydrogenation of refined Castor Oil.
Hydrogenated Castor Oil (HCO) is a hard, brittle, high melting point product that is practically odorless and tasteless.
Hydrogenated Castor Oil (HCO) is supplied in the form of flakes.


The Color of Hydrogenated Castor Oil (HCO) is cream to white.
Hydrogenated Castor Oil (HCO) is solid castor powder of high-melting-point.
Hydrogenated Castor Oil (HCO) is safely derived after the process of hydrogenation of refined castor oil.


Hydrogenated Castor Oil (HCO) is a non-hazardous as well as non-toxic product.
Hydrogenated Castor Oil (HCO) is insoluble in water and has limited solubility in the solvents.
Hydrogenated Castor Oil (HCO) is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.


Hydrogenated Castor Oil (HCO) is insoluble in water, limited solubility in the solvents, high applicability, stability and high-drop point.
Hydrogenated Castor Oil (HCO) is hard, brittle, solid castor wax which has a high-melting-point.
Hydrogenated Castor Oil (HCO) is derived after the safe hydrogenation process of refined castor oil.


Hydrogenated Castor Oil (HCO) is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.
Hydrogenated Castor Oil (HCO) is insoluble in water, limited solubility in the solvents, high applicability, stability and high-drop point.
Hydrogenated Castor Oil (HCO) is a white to slightly yellowish fine free-flowing powder


In topical formulations, Hydrogenated Castor Oil (HCO) is used to provide stiffness to creams and emulsions.
In oral formulations, Hydrogenated Castor Oil (HCO) is used to prepare sustained-release tablet and capsule preparations.
Hydrogenated Castor Oil (HCO) is also known as Synthetic Wax.


Hydrogenated Castor Oil (HCO) is white crystalline solid flakes.
Hydrogenated Castor Oil (HCO) finds a number of diversified uses due to its unique combination of physic-chemical properties.
Hydrogenated Castor Oil (HCO) is a hard, brittle, solid castor wax with a high melting point.


Derived through a safe hydrogenation process from refined castor oil, Hydrogenated Castor Oil (HCO) is available in the form of wax, powder, or flakes.
Hydrogenated Castor Oil (HCO) is known for its excellent stability, high-drop point, and limited solubility in solvents.
Hydrogenated Castor Oil (HCO) is a non-toxic and non-hazardous product that transforms into a clear transparent liquid when melted.


Hydrogenated Castor Oil (HCO) has excellent viscosity-modifying properties, making it ideal for improving grease and oil resistance.
Hydrogenated Castor Oil (HCO) is a hard, brittle, solid castor wax derived through a safe hydrogenation process.
Hydrogenated Castor Oil (HCO) has a high melting point and is available in the form of wax, powder, or flakes.
Hydrogenated Castor Oil (HCO) is insoluble in water and possesses excellent stability, high-drop point, and limited solubility in solvents.


USES and APPLICATIONS of HYDROGENATED CASTOR OIL (HCO):
Hydrogenated castor oil has been used as an antimicrobial agent for various detergent compositions, pharmaceutical preparations, and topical formulations.
Hydrogenated Castor Oil (HCO) has also been used as a polymerization aid for the production of insoluble polymers, including polyurethane elastomers.
Hydrogenated Castor Oil (HCO) is an extremely versatile oleochemical that has a number of industrial and manufacturing applications.


Because of its excellent resistance to moisture, Hydrogenated Castor Oil (HCO) works extremely well as a viscosity modifier, and it also provides significant improvement in grease and oil resistance.
Personal Care: There are multiple Hydrogenated Castor Oil (HCO) uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.


Waxes: Hydrogenated Castor Oil (HCO) works as a binding agent in synthetic and petroleum waxes, as it makes the wax harder and more resistant to crumbling.
Soaps and Detergents: Hydrogenated Castor Oil (HCO) is sometimes used as an emulsifying agent in liquid soaps and detergents to enhance the stability of the liquid formula.


Textiles: Hydrogenated Castor Oil (HCO) makes an effective processing agent in various textile manufacturing applications.
Lubricants and Greases: Hydrogenated Castor Oil (HCO) is used as a thickening agent in lithium grease and lithium complex grease, as well as multipurpose greases and metal-drawing lubricants.


Hydrogenated Castor Oil (HCO) has a very wide use in the industries like: Lubricants, Paper Coatings, Processing Aids, Polishes, Investment Castings, Inks, Pencil & Crayons, Cosmetics, Electrical Applications, Hot Melt Adhesives.
Hydrogenated Castor Oil (HCO) is also used in the cosmetics sector.


There are numerous applications of Hydrogenated Castor Oil (HCO) in various industrial segments, such as a slip additive in paints, plastics (PE), and inks and as a dispersing agent in carbon papers, inks, and plastic color master batches and as a dispersing additive and flow control in sealants, hot-melt adhesives, powder coatings, and more.


There are many applications such as lubricants, plastics, and multipurpose industrial greases.
Hydrogenated Castor Oil (HCO) has a very high oxidative stability and acts very effectively as an internal and external lubricant in polymers.
This is an oil wit flexibility and ductility for the manufacturer of industrial resins, plastics, elastomers, dielectric, rubber products in general.


Hydrogenated Castor Oil (HCO) is widely used in the production of multi-purpose calcium and lithium lubricating greases.
Lubricating greases produced from Hydrogenated Castor Oil (HCO) exhibit excellent resistances to oils and fats, water and solvents and they endue a long-life stability.


Hydrogenated Castor Oil (HCO) also is importand as thixotropic agent or as raw material in the production thereof for solvent-based coating systems.
Other technical application fields of Hydrogenated Castor Oil (HCO) are the use as processing aid for phenolic resins, polyethylene, PVC and rubber and as additive in the application of powder coatings. Non-drying alkyd resins can also be produced out of Hydrogenated Castor Oil (HCO).


Hydrogenated Castor Oil (HCO) is of importance concerning the production of hot melts like paper coatings for food packaging and the production of hot melt adhesives.
In several types of polishes (for cars, shoes, furniture) Hydrogenated Castor Oil (HCO) is an ingredient.


Another important field is the use of Hydrogenated Castor Oil (HCO) and its derivatives (e. g. ethoxylated HCO) in cosmetics like creams, lipsticks etc.
Hydrogenated Castor Oil (HCO) is used Adhesives, Emulsifiers, and Lubricants.
Hydrogenated Castor Oil (HCO) is a wax used in applications ranging from the manufacture of lithium and calcium greases, hot melts in sealants and coatings, mold release agents for plastic or rubber, paper coats, and personal care.


Hydrogenated Castor Oil (HCO) is hard and brittle with a high melting point, and is suitable for us as a structurant for antiperspirant sticks or lipstick.
Hydrogenated Castor Oil (HCO) — also called HCO or castor wax — is a hard, white, opaque vegetable wax.
Its resistance to moisture makes Hydrogenated Castor Oil (HCO) useful in many coatings, greases, cosmetics, polishes and similar applications.


Hydrogenated Castor Oil (HCO) is created by hydrogenating pure liquid castor oil, which is obtained from castor beans.
Hydrogenated Castor Oil (HCO) is heated under extreme pressure using a nickel catalyst during the hydrogenation process.
Afterward, the hydrogen creates saturated molecules of castor wax, which gives Hydrogenated Castor Oil (HCO) a higher melting point that allows it to remain solid at room temperature.


After hydrogenation, Hydrogenated Castor Oil (HCO) becomes hard and brittle to the touch.
greases uses of Hydrogenated Castor Oil (HCO): Lithium- and Calcium hydroxystearates dispersed in base oil to make multipurpose greases having higher dropping points, hardness, better rust-proofing, lubricity and durability than stearates.


Other lubricants: Hydrogenated Castor Oil (HCO) is used metal drawing lubes, PVC lubricants for PVC pipes, profiles, sheets, pharma tabletting, metal powders, ceramics.
Hydrogenated Castor Oil (HCO) is used as a thickener, emulsifier in cosmetics.


Hydrogenated Castor Oil (HCO) is used in ointments as well as fragrances.
Hydrogenated Castor Oil (HCO) is used manufacturing of candles, lipsticks and crayons.
Hydrogenated Castor Oil (HCO) is a hard brittle, high melting point waxy substance with faint characteristic of fatty wax odor and is tasteless.


Hydrogenated Castor Oil (HCO) is compatible with beeswax, carnauba and candelilla wax.
Hydrogenated Castor Oil (HCO) is relatively insoluble in most organic solvents though it will dissolve in a number of solvents and oils at an elevated temperature but on cooling will form gels or a paste like mass.


Hydrogenated Castor Oil (HCO) forms a smooth, stable anionic emulsion with emulsifiers and triethanolamine stearate. Hydrogenated Castor Oil (HCO) can also be emulsified with a cationic emulsifying agent, making emulsions that are also stable.
Hydrogenated Castor Oil (HCO) is mainly used in plastics, textiles, lubricants etc.


Hydrogenated Castor Oil (HCO) is used Castor Oils & Castor Oil Derivatives, Flavor & Fragrance, Inks & Digital Inks, Lubricant & Grease, Plastic, Resin & Rubber, Nutritionals
Hydrogenated Castor Oil (HCO) finds a number of diversified uses due to its unique combination of physicochemical properties.


Hydrogenated Castor Oil (HCO) is used in the manufacture of multipurpose Lithium/Calcium grease and high-performance aviation grease.
Hydrogenated Castor Oil (HCO) is used in the manufacture of soaps & cosmetics.
Hydrogenated Castor Oil (HCO) is used as mould release agent in the processing of plastics and rubbers.


Hydrogenated Castor Oil (HCO) is used as a component of specialty wax blends like pencils, crayons, lipsticks and anti-deodorant sticks.
Hydrogenated Castor Oil (HCO) is used in the manufacture of hot-melt coatings and sealant requiring resistance to water.
Hydrogenated Castor Oil (HCO) is used as a coating agent for paper & as anti-foaming agent.


Hydrogenated Castor Oil (HCO) is used in the manufacture of Automotive refinish Acrylics.
Hydrogenated Castor Oil (HCO) is used rheological agent that provides thixotropic in paints, coatings, inks, adhesives, sealants and numerous industrial compositions.


Hydrogenated Castor Oil (HCO) is used thick film chlorinated rubber, epoxy and vinyl coating.
Hydrogenated Castor Oil (HCO) is used flame Retardant and anti-static agent for fiber.
Hydrogenated Castor Oil (HCO) is used manufacture of Spin finish oil for polyamide fiber.


Hydrogenated Castor Oil (HCO) is used in preparation of ointments, emulsified virus vaccines, sustained release capsules, wetting/bodying agent, face paint.
Hydrogenated Castor Oil (HCO) is used as plasticizer for cellulosic.
Hydrogenated Castor Oil (HCO) is used processing aid for Colour concentrates.


Hydrogenated Castor Oil (HCO) is used surface treatment agents.
Hydrogenated Castor Oil (HCO) is used in the manufacture of hot melt adhesives used in packaging books, binding footwear, carpet backing and in product assembly.


Hydrogenated Castor Oil (HCO) is used anti-tack and slip additives for processing plastics.
Hydrogenated Castor Oil (HCO) is used in the manufacture of specialty chemicals for applications such as metal working, plasticizers and textile auxiliaries in the form of derivatives such as esters, ethylates, sulfates etc.


Hydrogenated Castor Oil (HCO) is soluble in both water and oil and is traditionally used to emulsify and solubilize oil-in-water formulations.
Its foam-enhancing properties make Hydrogenated Castor Oil (HCO) ideal for use in liquid cleansers.
As a surfactant, Hydrogenated Castor Oil (HCO) helps to decrease the surface tension between multiple liquids or between liquids and solids.


Furthermore, Hydrogenated Castor Oil (HCO) helps to remove the grease from oils and causes them to become suspended in the liquid.
Hydrogenated Castor Oil (HCO) is used in the following products: polymers, lubricants and greases, paper chemicals and dyes, cosmetics and personal care products and pharmaceuticals.


Release to the environment of Hydrogenated Castor Oil (HCO) can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance and in the production of articles.
Hydrogenated Castor Oil (HCO) is used in the following areas: formulation of mixtures and/or re-packaging.


Hydrogenated Castor Oil (HCO) is used in the following products: washing & cleaning products, polymers, metal surface treatment products, textile treatment products and dyes, lubricants and greases and pH regulators and water treatment products.


Hydrogenated Castor Oil (HCO) is used for the manufacture of: chemicals, , textile, leather or fur and plastic products.
Release to the environment of Hydrogenated Castor Oil (HCO) can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid and for thermoplastic manufacture.


Release to the environment of Hydrogenated Castor Oil (HCO) can occur from industrial use: manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.
Hydrogenated Castor Oil (HCO) is used for Coatings and Greases.


Hydrogenated Castor Oil (HCO) is utilized in the Manufacture of Waxes, Polishes, Carbon Paper, Candles and Crayons.
Hydrogenated Castor Oil (HCO) finds Use in Cosmetics, Hair Dressing, Ointments, and in Preparation of Hydroxyl-stearic Acid.
Hydrogenated Castor Oil (HCO) is used as a Paint Additive, Pressure Mould Release Agent in the Manufacture of Formed Plastics and Rubber Goods.


It is this insolubility that makes Hydrogenated Castor Oil (HCO) valuable to the lubricants markets. It is perfect for metal drawing lubricants and multipurpose industrial greases.
Hydrogenated Castor Oil (HCO) is used in polishes, cosmetics, electrical capacitors, carbon paper, lubrication, and coatings and greases where resistance to moisture, oils and petrochemical products is required.


Hydrogenated Castor Oil (HCO) is used as the Reaction Itself is Exothermic, the Chief Energy Requirements are in the Production of Hydrogen, Warming of the Oil, Pumping, and Filtering.
Hydrogenated Castor Oil (HCO) is known for its versatility and is used in various industries and applications due to its unique characteristics.


Inks & Toner: Hydrogenated Castor Oil (HCO) can be used in the formulation of environmentally friendly inks and toners, contributing to sustainable printing and imaging solutions.
Lubricants & Greases: In lubricants and greases, Hydrogenated Castor Oil (HCO) may act as a natural and renewable ingredient, providing eco-conscious solutions for machinery and mechanical systems.


Adhesives & Sealants: Hydrogenated Castor Oil (HCO) is employed in adhesives and sealants, offering natural and renewable components for eco-friendly bonding solutions.
Coatings & Paints: Hydrogenated Castor Oil (HCO) can be incorporated into coatings and paints to enhance their performance, sustainability, and eco-friendliness.


Packaging: Hydrogenated Castor Oil (HCO) can be used in eco-conscious packaging materials and coatings, promoting sustainability in packaging solutions.
Cosmetics & Care: In cosmetics, personal care products, and skincare formulations, Hydrogenated Castor Oil (HCO) contributes to natural and eco-friendly products.


Pharmaceuticals: Hydrogenated Castor Oil (HCO) may find applications in pharmaceutical formulations and drug delivery systems.
Tire & Rubber: In the tire and rubber industry, Hydrogenated Castor Oil (HCO) can be employed in rubber compound formulations to enhance processing and performance.


Wax Blenders: Hydrogenated Castor Oil (HCO) is used in the formulation of wax blends for various applications, providing eco-friendly alternatives in wax-based products.
Cleaning & Household: Hydrogenated Castor Oil (HCO) can find applications in eco-friendly cleaning products and household items, contributing to sustainable and natural alternatives.


Agriculture: Hydrogenated Castor Oil (HCO) may have agricultural applications, such as in crop protection formulations and soil conditioning products, promoting sustainable agricultural practices.
Hydrogenated Castor Oil (HCO) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Hydrogenated Castor Oil (HCO) is used in the following products: washing & cleaning products, lubricants and greases, adhesives and sealants, polishes and waxes, fertilisers, coating products and air care products.


Other release to the environment of Hydrogenated Castor Oil (HCO) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Hydrogenated Castor Oil (HCO) can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release, industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).


Other release to the environment of Hydrogenated Castor Oil (HCO) is likely to occur from: indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Hydrogenated Castor Oil (HCO) can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles.


Hydrogenated Castor Oil (HCO) can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), plastic (e.g. food packaging and storage, toys, mobile phones), leather (e.g. gloves, shoes, purses, furniture) and rubber (e.g. tyres, shoes, toys).


Hydrogenated Castor Oil (HCO) is used in the following products: washing & cleaning products and polishes and waxes.
Hydrogenated Castor Oil (HCO) is used in the following areas: formulation of mixtures and/or re-packaging.
Hydrogenated Castor Oil (HCO) is used for the manufacture of: chemicals and .


Other release to the environment of Hydrogenated Castor Oil (HCO) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).


Hydrogenated Castor Oil (HCO) is used as a thickener, emulsifier in cosmetics.
Hydrogenated Castor Oil (HCO) is used in ointments as well as fragrances.
Hydrogenated Castor Oil (HCO) is used manufacturing of candles, lipsticks and crayons


Hydrogenated Castor Oil (HCO) is used as a viscosity modifier to improve the grease and oil resistance.
The dispersal level of Hydrogenated Castor Oil (HCO) is good in powder coatings, hot-melt adhesives, elastomer, sealants etc.
Hydrogenated Castor Oil (HCO) is accessible with high-drop point, high applicability and good stability.


Hydrogenated Castor Oil (HCO) is used as the viscosity modifier, made to improve resistance against grease and oil.
Hydrogenated Castor Oil (HCO) has specific dispersal level that ensures its good use in the powder coatings, elastomer, hot-melt adhesives others.
Hydrogenated Castor Oil (HCO) is used for the production of daily cosmetics, shoe polish, pharmaceutical ointment, is the raw material for the preparation of 12-hydroxy stearic acid.


Hydrogenated Castor Oil (HCO) is used as a viscosity modifier to improve the grease and oil resistance.
The dispersal level of Hydrogenated Castor Oil (HCO) is good in powder coatings, hot-melt adhesives, elastomer, sealants etc.
Hydrogenated Castor Oil (HCO) is used Hot-melt adhesive in packaging, Bookbinding, Footwear, Carpet back, Product Assembly, Thick film chlorinated rubber, Epoxy and vinyl coating, Personal care and cosmetic industries, and Micronized Hydrogenated Castor Oil (HCO) derivative.


Hydrogenated Castor Oil (HCO) is used as a viscosity modifier to improve grease and oil resistance.
The dispersal level of Hydrogenated Castor Oil (HCO) is good in powder coatings, hot-melt adhesives, elastomers, sealants, etc.
As Hydrogenated Castor Oil (HCO) suppliers, we follow strict protocols to ensure that only the best quality product reaches our customers.


Hydrogenated Castor Oil (HCO) is used in pharmaceutical applications, manufacture of greases and lubricants, and range of cosmetics & toiletries.
Hydrogenated Castor Oil (HCO) is hydrogenated castor powder for pharmaceutical application used as consistency factor in topical formulations, as lipohphillic lubricant in tablets and capsules and as plasticizer in solid dispersions using spray drying, melt granulation or hot melt extrusion processes.


Hydrogenated Castor Oil (HCO) complies with IPEC GMP standards for critical pharmaceutical applications.
Hydrogenated Castor Oil (HCO) is used as a consistency factor in topical formulations, as alipophillic lubricant in tablets and capsules, and as a plasticizer in solid dispersions using spray drying, melt granulation or hot melt extrusion processes.


Hydrogenated Castor Oil (HCO) ensures risk reduction in pharmaceutical applications and meets all relevant regulatory needs.
Hydrogenated Castor Oil (HCO) is used as retardation component and pressing agent for the preparation of tablets for pharmaceutical application.
Hydrogenated Castor Oil (HCO) is used for all skin care applications, particularly for sticks.


Hydrogenated Castor Oil (HCO) is an extremely versatile oleochemical that has a number of industrial and manufacturing applications: Viscosity Modifier, Plastics, Waxes, Personal Care, Soap, Detergent, Textiles, Lubricants and Greases.
Hydrogenated Castor Oil (HCO) performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.


It is also useful in the preparation of various polyurethane coating formulas.here are multiple Hydrogenated Castor Oil (HCO) uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.
This versatile ingredient, Hydrogenated Castor Oil (HCO), finds applications in various industries due to its exceptional properties.


Hydrogenated Castor Oil (HCO) is widely used in powder coatings, hot-melt adhesives, elastomers, and sealants.
Hydrogenated Castor Oil (HCO) is used in a variety of industrial applications.
Hydrogenated Castor Oil (HCO) is utilized in the production of greases, lubricants, and adhesives to improve their resistance to grease and oil.


Hydrogenated Castor Oil (HCO) is also used in rubber, plastic, polishes, and coatings to enhance their performance and durability.
Its high-drop point and stable nature make Hydrogenated Castor Oil (HCO) ideal for applications that require resistance to heat and chemicals.
Hydrogenated Castor Oil (HCO) is particularily suitable for formulation of sensitive APIs.


-Plastics uses of Hydrogenated Castor Oil (HCO):
Hydrogenated Castor Oil (HCO) performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.
Hydrogenated Castor Oil (HCO) is also useful in the preparation of various polyurethane coating formulas.


-cosmetics uses of Hydrogenated Castor Oil (HCO): Hydrogenated Castor Oil (HCO) of different melting points used in lipsticks, deodorant and antiperspirant sticks, cosmetic creams.
slip additive in inks, paints, plastics (PE).

Hydrogenated Castor Oil (HCO) is used dispersing agent in plastic colour master batches, carbon papers, inks.
Hydrogenated Castor Oil (HCO) is used flow control and dispersing additive in powder coatings, hot-melt adhesives and sealants.
Hydrogenated Castor Oil (HCO) is used shoe polishing, furniture polishing creams.


-Pharmaceutical Applications
Hydrogenated Castor Oil (HCO) is a hard wax with a high melting point used in oral and topical pharmaceutical formulations.
In topical formulations, Hydrogenated Castor Oil (HCO) is used to provide stiffness to creams and emulsions.

In oral formulations, Hydrogenated Castor Oil (HCO) is used to prepare sustained-release tablet and capsule preparations; the Hydrogenated Castor Oil (HCO) may be used as a coat or to form a solid matrix.
Hydrogenated Castor Oil (HCO) is additionally used to lubricate the die walls of tablet presses; and is similarly used as a lubricant in food processing.
Hydrogenated Castor Oil (HCO) is also used in cosmetics.


-Applications of Hydrogenated Castor Oil (HCO) in Various Industries:
Hydrogenated Castor Oil (HCO) finds a wide range of applications across different sectors.
Its versatility and excellent properties make Hydrogenated Castor Oil (HCO) an essential ingredient in various industries.


-Pharmaceutical and Cosmetic Applications of Hydrogenated Castor Oil (HCO):
The pharmaceutical and cosmetic industries extensively use Hydrogenated Castor Oil (HCO).
Hydrogenated Castor Oil (HCO) is used as a key ingredient in the production of ointments, emulsified virus vaccines, sustained-release capsules, and face paint.

Its ability to act as a wetting and bodying agent makes Hydrogenated Castor Oil (HCO) useful in the preparation of different pharmaceutical formulations.
In the cosmetic industry, Hydrogenated Castor Oil (HCO) is used in the manufacture of soaps, shampoos, creams, and lotions due to its stable nature and high-drop point


-Industrial Applications of Hydrogenated Castor Oil (HCO) in the Production of Greases, Lubricants, and Adhesives:
Hydrogenated Castor Oil (HCO) is widely used in the production of greases, lubricants, and adhesives.
Its viscosity-modifying properties make Hydrogenated Castor Oil (HCO) an excellent choice for improving the grease and oil resistance of these products.
The powder form is particularly suitable for hot-melt adhesives, where Hydrogenated Castor Oil (HCO) enhances the adhesion and strength of the adhesive.
Additionally, Hydrogenated Castor Oil (HCO) is used as a mold release agent in the processing of plastics and rubbers.


-Use of Hydrogenated Castor Oil (HCO) in Rubber, Plastic, Polishes, and Coatings:
Hydrogenated Castor Oil (HCO) plays a crucial role in the rubber, plastic, polishes, and coatings industries.
It is known for its excellent dispersal level in powder coatings and its ability to enhance the performance of elastomers and sealants.
In rubber and plastic applications, it improves the resistance to moisture, oil, and other petrochemical products.
Furthermore, it finds use in polishes and coatings where it provides durability and a glossy finish


-Topical formulations:
In topical formulations, Hydrogenated Castor Oil (HCO) can be used as consistency factor to enhance the viscosity of the formulation.
The typical concentration at about 0.1-2% Hydrogenated Castor Oil (HCO) is compatible with most natural vegetable and animal waxes and can therefore be used in combination with fatty alcohols and other consistency factors.

Similar to emollients, waxes affect the sensory profile and the stability of a topical formulation.
They are solid at ambient temperatures and stabilize emulsions as the viscosity is increased by formation of lamellar structures in oil-in-water formulations.

Furthermore Hydrogenated Castor Oil (HCO) has a special advantage because of its high melting point and is able to support the formulation stability particularly at elevated temperatures.


-Lubricant in tablet and capsule formulations:
Lubricants prevent ingredients from clumping together and from sticking to the tablet punches or capsule filling machine.
Lubricants also ensure that tablet formulations and ejection can occur with low friction.

Common minerals like talc or silica, and fats, e.g. vegetable stearin, magnesium stearate or stearic acid, are most frequently used lubricants in tablets or hard gelatin capsules.
Lubricants are added in small quantities to tablet or capsule formulations to improve certain processing characteristics.

In tablet formulations Kolliwax® HCO can be used as a lubricant as an effective alternative to magnesium stearate.
Hydrogenated Castor Oil (HCO) is compatible to a large number of actives and does not provide a metallic taste.
Hydrogenated Castor Oil (HCO) is particularly suitable for formulation of sensitive APIs.


-Plasticizer in solid dispersions:
In solid dispersions, Hydrogenated Castor Oil (HCO) is used as plasticizer in solid polymeric matrices.
Hydrogenated Castor Oil (HCO) is suitable for melt granulation, spray drying and hot melt extrusion processes.



WHAT IS HYDROGENATED CASTOR OIL (HCO) USED FOR?
Hydrogenated Castor Oil (HCO) is a natural powerhouse ingredient overflowing with benefits for both hair and skin.

*Skin care:
Hydrogenated Castor Oil (HCO) acts as an outstanding emollient that deeply nourishes the surface and prevents moisture loss.
Hydrogenated Castor Oil (HCO) soothes the skin against sunburn and treats signs of aging like wrinkles.
Hydrogenated Castor Oil also has antibacterial properties making it potent for fighting acne


*Cosmetic products:
Apart from its emollient properties, Hydrogenated Castor Oil (HCO) is quite beneficial as a binding agent that keeps formulations together and stabilizes them.
Hydrogenated Castor Oil (HCO) is a great thickening agent and gives products a rich, luxurious consistency.
In cosmetics, Hydrogenated Castor Oil (HCO) works wonders for dry skin and lips


*Hair care:
Hydrogenated Castor Oil (HCO) has remarkable perks for overall hair health.
Hydrogenated Castor Oil (HCO) aids the rapid growth of hair, eyelashes, and eyebrows while keeping them healthy and nourished.
Long-term use of Hydrogenated Castor Oil (HCO) on hair leaves them lustrous, thick, and frizz-free



ORIGIN OF HYDROGENATED CASTOR OIL (HCO):
Castor oil is derived from castor beans, also known as ricinus communis, which is native to India, China, and Brazil.
This oil undergoes a hydrogenation process which involves reacting castor oil with hydrogen gas in the presence of a catalyst, typically nickel or palladium.

During hydrogenation, unsaturated fatty acids present in castor oil undergo saturation, converting double bonds into single bonds.
This results in a more solid and stable form of castor oil with improved oxidative stability and increased melting point.
The resulting Hydrogenated Castor Oil is then purified to remove impurities and make it safe for use in cosmetics.



WHAT DOES HYDROGENATED CASTOR OIL (HCO) DO IN A FORMULATION?
*Binding
*Emollient
*Skin conditioning
*Soothing
*Viscosity controlling



SAFETY PROFILE OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil is non-toxic and extremely safe for use on hair and skin.
However, cosmetic-grade Hydrogenated Castor Oil is cleaned of all impurities and does not pose any risks.
Hydrogenated Castor Oil (HCO) is also non-comedogenic, providing a safe solution for hydration without clogging the pores.
Further, Hydrogenated Castor Oil (HCO) is vegan, halal, and kosher-certified.



ALTERNATIVES OF HYDROGENATED CASTOR OIL (HCO):
*HYDROGENATED VEGETABLE OIL



CHEMICAL PROPERTIES OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated castor oil occurs as a fine, almost white or pale yellow powder or flakes. The PhEur 6.0 describes hydrogenated castor oil as the oil obtained by hydrogenation of virgin castor oil. It consists mainly of the triglyceride of 12-hydroxystearic acid.



FUNCTIONS OF HYDROGENATED CASTOR OIL (HCO):
*Emulsifier,
*Plasticizer



SAFETY OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil (HCO) is used in oral and topical pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material.



STORAGE OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil (HCO) is stable at temperatures up to 1508℃. Clear, stable, chloroform solutions containing up to 15% w/v of Hydrogenated Castor Oil (HCO) may be produced.
Hydrogenated Castor Oil (HCO) may also be dissolved at temperatures greater than 908℃ in polar solvents and mixtures of aromatic and polar solvents, although the Hydrogenated Castor Oil (HCO) precipitates out on cooling below 908℃.
Hydrogenated Castor Oil (HCO) should be stored in a well-closed container in a cool, dry place.



INCOMPATIBILITIES OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil (HCO) is compatible with most natural vegetable and animal waxes.



PRODUCTION METHODS OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil (HCO) is prepared by the hydrogenation of castor oil using a catalyst.



UNIQUE PROPERTIES OF HYDROGENATED CASTOR OIL (HCO):
*Emollient:
Hydrogenated Castor Oil (HCO) has emollient properties, making it suitable for skin-care and cosmetic products, providing moisturization and a smooth texture.

*Thickening:
Hydrogenated Castor Oil (HCO) can serve as a thickening agent in various formulations, enhancing their viscosity and stability.

*Lubrication:
Hydrogenated Castor Oil (HCO) functions as a lubricant, reducing friction and providing a smooth surface in pharmaceutical and industrial applications.

*Release Agent:
In food processing, Hydrogenated Castor Oil (HCO) acts as a release agent, preventing sticking and enhancing the release of products from molds and equipment.

*Plasticizer:
In plastics and coatings, Hydrogenated Castor Oil (HCO) can function as a plasticizer, improving flexibility and durability.

*Alternative for:
The choice of using hydrogenated castor oil depends on specific application requirements.
Alternatives may include other types of oils, waxes, or chemical compounds that provide similar properties, depending on the desired characteristics and environmental considerations.

The selection is influenced by factors such as emollient properties, thickening ability, lubrication, release properties, and cost considerations.
Hydrogenated Castor Oil (HCO) is preferred when its unique combination of properties aligns with the application's needs, particularly in cosmetics, pharmaceuticals, and food processing, where its safety and performance benefits are valued.



KEY FEATURES OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil (HCO) is solid castor powder of high-melting-point.
This is safely derived after the process of hydrogenation of refined castor oil.
Hydrogenated Castor Oil (HCO) is a non-hazardous as well as non-toxic product.



BENEFITS OF HYDROGENATED CASTOR OIL (HCO):
*At room temperature Hydrogenated Castor Oil (HCO) is a hard wax with a high melting point (85-88°C)
*Hydrogenated Castor Oil (HCO) has unique particle size distribution
*Hydrogenated Castor Oil (HCO) is particularly suitable for the formulation of sensitive APIs
*Hydrogenated Castor Oil (HCO) is compatible with several natural vegetable and animal waxes, as well as fatty alcohols to enhance viscosity of topical formulations
*Hydrogenated Castor Oil (HCO) is suitable as a plasticizer for melt granulation, spray drying, Hot melt extrusion



FUNCTIONALITIES OF HYDROGENATED CASTOR OIL (HCO):
*Additives,
*Lubricants,
*Film formers,
*Viscosity modifiers



WHAT ARE THE KEY BENEFITS OF USING HYDROGENATED CASTOR OIL (HCO) IN COSMETICS?
Hydrogenated Castor Oil (HCO) offers several benefits when used in cosmetics.
Hydrogenated Castor Oil (HCO) acts as an excellent emollient, providing hydration and moisturization to the skin.

Hydrogenated Castor Oil (HCO) also helps in the formulation of various cosmetic products such as creams, lotions, and shampoos by enhancing their stability and texture.
The high-drop point of Hydrogenated Castor Oil (HCO) ensures that the products remain stable even at elevated temperatures.

In conclusion, Hydrogenated Castor Oil (HCO) is a versatile ingredient with various applications in pharmaceuticals, cosmetics, and industrial sectors.
Its unique properties and exceptional stability make Hydrogenated Castor Oil (HCO) an ideal choice for improving the performance of greases, lubricants, adhesives, rubber, plastic, polishes, and coatings.



FEATURES OF HYDROGENATED CASTOR OIL (HCO):
Hydrogenated Castor Oil (HCO) is a hard, wax-like substance extracted from castor oil beans.
There is also a petroleum-based formula of Hydrogenated Castor Oil (HCO) known as PEG-40.
The Hydrogenated Castor Oil (HCO) chemical formula of this material is C57H110O9(CH2CH2O)n.



PHYSICAL and CHEMICAL PROPERTIES of HYDROGENATED CASTOR OIL (HCO):
Appearance: White to creamish flakes or powder
Density (20°C): 0.970
Refractive index: N.A.
Melting point (°C): 83 - 87
Acid Value (mg KOH/g): 0.0 - 3.0
Gardner color: 0.0 - 3.0
Hydroxyl value (mg KOH/g): 180.0000
Melting point (°C): 85 - 88
Nickel content (ppm): 3
Saponification value (mg KOH/g): 0
Specific Gravity (25°C): 1.02
Color: White to Pale Yellowish
Appearance @ 20°C: Solid (Mobile liquid @ 30°C)
Odor: Almost none

Density: 0.97g/cm3 at 20℃
Vapor pressure: 0Pa at 20℃
Solubility: Practically insoluble in water; soluble in acetone,
chloroform, and methylene chloride.
Form: Powder
Dielectric constant: 10.3 (27℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 18.75
FDA 21 CFR: 178.3280; 175.300; 176.170; 177.1200; 177.1210
Indirect Additives used in Food Contact Substances: CASTOR OIL, HYDROGENATED
EWG's Food Scores: 1
FDA UNII: ZF94AP8MEY
EPA Substance Registry System: Hydrogenated castor oil (8001-78-3)
Appearance: White flakes or powder

Odor: Like hardened vegetable oil
pH: Neutral
Boiling Point: > 300°C
Melting Point: 82 - 87°C
Flash Point: Above 310°C
Flammability (solid, gas): None
Auto flammability: None
Explosive Properties: Dust explodable
Oxidizing Properties: None
Vapor Pressure: Not applicable
Relative Density: About 0.99 at 25°C
Solubility - Water solubility: Insoluble
Fat solubility: Insoluble in most organic solvents at room temperature
Partition coefficient: n-octanol/water: Not available
Melting Point: 85°C
Solubility: Insoluble in water
Viscosity: High

Appearance: White flakes
Iodine Value, gI2/100g: 3 MAX
Saponification Value, mg KOH/g: 175 - 185
Acid Value, mg KOH/g: 3 MAX
Hydroxyl Value, mg KOH/g: 155 MIN
Melting Point, °C: 84 - 88
Gardner Color: 3 MAX
CAS: 8001-78-3
EINECS: 232-292-2
Density: 0.97 g/cm3 at 20°C

Solubility: Practically insoluble in water; soluble in acetone,
chloroform, and methylene chloride.
Vapor Pressure: 0 Pa at 20°C
Appearance: Powder
Storage Condition: Room Temperature
Stability: Stable.
Additional Information:
Appearance: White to pale yellow powder, lump, or flake.
Base Number: Not more than 4.0.
Melting Point: 85-88 °C.
Hydroxyl Value: 150-165.
Iodine Value: Not more than 5.0.
Saponification Value: 176-182.
Color: 3



FIRST AID MEASURES of HYDROGENATED CASTOR OIL (HCO):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of HYDROGENATED CASTOR OIL (HCO):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HYDROGENATED CASTOR OIL (HCO):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROGENATED CASTOR OIL (HCO):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROGENATED CASTOR OIL (HCO):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of HYDROGENATED CASTOR OIL (HCO):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

HYDROGENATED CASTOR OIL (HCO)
Hydrogenated castor oil (HCO) is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated castor oil (HCO) is a hard product with a high melting point.
Hydrogenated castor oil (HCO) is almost odourless and tasteless.

CAS Number: 8001-78-3
EINECS Number: 232-292-2

Hydrogenated Castor Oil, 8001-78-3, Castor Oil, Hydrogenated, 232-292-2, Castor Wax, Castor oil hydrogenated, Castorwax, ZF94AP8MEY, 1,2,3-Propanetriol tri(12-hydroxystearate), 12-Hydroxyoctadecanoic acid, 1,2,3-propanetriyl ester, CASTOR OIL, HYDROGENATED (EP IMPURITY), CASTOR OIL, HYDROGENATED (EP MONOGRAPH), CASTOR OIL,HYDROGENATED, Castorwax MP-70, Castorwax MP-80, Castorwax NF, Caswell No. 486A, DTXSID8027666, EC 232-292-2, EINECS 232-292-2, EPA Pesticide Chemical Code 031604, HYDROGENATED CASTOR OIL (II), HYDROGENATED CASTOR OIL (USP-RS), LUBLIWAX, OPALWAX, Olio di ricino idrogenato, Rice syn wax, UNII-ZF94AP8MEY, Unitina HR.

Hydrogenated castor oil (HCO) is supplied in flakes and powder. Hydrogenated castor oil is cream to white coloured.
Hydrogenated castor oil (HCO) occurs as a fine, almost white or pale yellow powder or flakes.
The PhEur 6.0 describes Hydrogenated castor oil (HCO) as the oil obtained by hydrogenation of virgin castor oil.

Hydrogenated castor oil (HCO) consists mainly of the triglyceride of 12-hydroxystearic acid.
Hydrogenated castor oil (HCO) is a hard, white, opaque vegetable wax.
Hydrogenated castor oil (HCO) is resistance to moisture makes it useful in many coatings, greases, cosmetics, polishes and similar applications.

Hydrogenated castor oil (HCO) is created by hydrogenating pure liquid castor oil, which is obtained from castor beans.
Hydrogenated castor oil (HCO) is heated under extreme pressure using a nickel catalyst during the hydrogenation process.
Afterward, the hydrogen creates saturated molecules of Hydrogenated castor oil (HCO), which gives the oil a higher melting point that allows it to remain solid at room temperature.

After hydrogenation, Hydrogenated castor oil (HCO) becomes hard and brittle to the touch.
Hydrogenated Castor Oil (HCO) is a derivative of castor oil that undergoes a hydrogenation process.
Hydrogenated castor oil (HCO) is obtained from the seeds of the castor plant (Ricinus communis), and hydrogenation involves the addition of hydrogen to the oil in the presence of a catalyst.

The hydrogenation process changes the chemical structure of Hydrogenated castor oil (HCO) by converting some of the unsaturated fatty acids into saturated ones.
This results in a product with altered physical and chemical properties compared to regular Hydrogenated castor oil (HCO).
The Hydrogenated castor oil (HCO) process makes the oil more stable and less prone to oxidation, giving it enhanced properties for certain applications.

Hydrogenated Castor Oil (HCO) is a wax-like solid at room temperature.
Hydrogenated castor oil (HCO) is derived from Castor Oil (extracted from the seeds of "Ricinus communis L.") by controlled hydrogenation.
Hydrogenated castor oil (HCO) is produced in form of flakes and powder.

Hydrogenated castor oil (HCO) is widely used in the production of multi-purpose calcium and lithium lubricating greases.
Lubricating greases produced from Hydrogenated castor oil (HCO) exhibit excellent resistances to oils and fats, water and solvents and they endue a long-life stability.
Hydrogenated castor oil (HCO) also is importand as thixotropic agent or as raw material in the production thereof for solvent-based coating systems.

Other technical application fields are the use as processing aid for phenolic resins, polyethylene, PVC and rubber and as additive in the application of powder coatings.
Non-drying alkyd resins can also be produced out of Hydrogenated castor oil (HCO).
Hydrogenated castor oil (HCO) is of importance concerning the production of hot melts like paper coatings for food packaging and the production of hot melt adhesives.

In several types of polishes (for cars, shoes, furniture) Hydrogenated castor oil (HCO) is an ingredient.
Another important field is the use of Hydrogenated castor oil (HCO) and its derivatives (e. g. ethoxylated HCO) in cosmetics like creams, lipsticks etc. .
Hydrogenated castor oil (HCO) is a compound attained by the hydrogenation of refined castor oil.

Hydrogenated castor oil (HCO) is a hard, waxy, white to cream colored product with a high melting point of 83 to 87 C°, and is nearly tasteless and odorless.
There are numerous applications in various industrial segments, such as a slip additive in paints, plastics (PE), and inks and as a dispersing agent in carbon papers, inks, and plastic color master batches and as a dispersing additive and flow control in sealants, hot-melt adhesives, powder coatings, and more.
Hydrogenated castor oil (HCO), also called Castor Wax, is a hard, brittle, high melting solid which is tasteless and odourless.

Chemically Hydrogenated castor oil (HCO) is the triglyceride, which mainly consists of 12-Hydroxy Stearic Acid.
Hydrogenated castor oil (HCO) is insoluble in water and solubility in many organic solvents is also very limited.
Hydrogenated castor oil (HCO) is available as flakes or powder which melts to a clear transparent liquid.

Hydrogenated castor oil (HCO) is a non-toxic, non-hazardous material.
Hydrogenated castor oil (HCO) is used in pharmaceutical applications, manufacture of greases and lubricants, and range of cosmetics & toiletries.
Hydrogenated castor oil (HCO) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil.

Hydrogenated Castor Oil (HCO) is a wax like compound obtained by the controlled hydrogenation of refined Castor Oil.
Hydrogenated castor oil (HCO) is a hard, brittle, high melting point product that is practically odourless and tasteless.
Hydrogenated castor oil (HCO) is supplied in the form of flakes or as powder.

The colour of Hydrogenated castor oil (HCO) is cream to white.
When melted Hydrogenated castor oil (HCO) is clear, transparent to straw coloured.
Hydrogenated castor oil (HCO) is a white to yellow pasty liquid with a faint odor.

Hydrogenated castor oil (HCO) is ideal for use in a wide range of applications in many industries, including Adhesives, Cosmetics, Greases, Inks, Lubricants, Personal care, Pharmaceuticals, Plastics, Rubber, Soaps, Textiles, and Urethanes.
Hydrogenated castor oil (HCO) is produced out of refined castor oil.

Hydrogenated castor oil (HCO) will be mixed with the catalyst nickel in a reactor and reched under addition of an hydrogen gas a temperature of 140°C.
During this process mainly the Iodine content will be reduced to a required value.
In the following filtration the added catalyst will be removed.

Finally the liquid oil will be brought over a cooling-drum into his flaked form.
Hydrogenated castor oil (HCO) is a white to slightly yellowish, fine, free-flowing powder.
Hydrogenated castor oil (HCO) is used as retardation component and pressing agent for the preparation of tablets for pharmaceutical application.

Hydrogenated castor oil (HCO), also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications.
Hydrogenated castor oil (HCO) refers to a chemical process where an unsaturated compound is combined with hydrogen to produce saturation.
In the case of Hydrogenated castor oil (HCO), this increases the oil’s stability and raises its melting point, transforming it into a solid at room temperature.

Hydrogenated castor oil (HCO) is insoluble in water and most types of organic solvents.
This makes Hydrogenated castor oil (HCO) extremely valuable in the manufacturing of lubricants and industrial greases.
However, Hydrogenated castor oil (HCO) is soluble in hot solvents.

Hydrogenated castor oil (HCO) also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities.
Hydrogenated castor oil (HCO) is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps.
Hydrogenated castor oil (HCO), also known as Castor Wax, is a hard, brittle, high melting odorless solid wax.

A triglyceride mainly of Hydrogenated castor oil (HCO) that is insoluble in water, these are available as fully hydrogenated flakes and powders, partially hydrogenated, and in liquid form which is non-toxic and non-hazardous material.
Hydrogenated castor oil (HCO) has a very wide use in the industries like: Lubricants, Paper Coatings, Processing Aids, Polishes, Investment Castings, Inks, Pencil & Crayons, Cosmetics, Electrical Applications, Hot Melt Adhesives.
Hydrogenated castor oil (HCO) is supplied in the form of flakes or as powder.

The colour of Hydrogenated castor oil (HCO) is cream to white.
Hydrogenated castor oil (HCO) is an extremely versatile oleochemical that has a number of industrial and manufacturing applications: Viscosity Modifier, Plastics, Waxes, Personal Care, Soap, Detergent, Textiles, Lubricants and Greases.
Hydrogenated castor oil (HCO) performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.

Hydrogenated castor oil (HCO) is also useful in the preparation of various polyurethane coating formulas.
Hydrogenated castor oil (HCO) is a versatile integrant for various applications.
As Hydrogenated castor oil (HCO) reduces atmospheric moisture pick-up during handling and mixing, it becomes an essential additive agent for substantial applications.

Hydrogenated castor oil (HCO) is odourless and is available in wax, powder, or flake form with high-melting-point.
These different forms are used as a viscosity modifier and for improvement in grease and oil resistance.
Hydrogenated castor oil (HCO) in cosmetics is a popular addition as it is soluble in both water and oil and has foam-enhancing properties.

Therefore one can easily find Hydrogenated castor oil (HCO) in skincare products like moisturizers as well as hair care cosmetics.
Hydrogenated castor oil (HCO) by Hannong Chemicals acts as a non-ionic surfactant, emulsifier, solubilizer and dispersant.
Hydrogenated castor oil (HCO) is recommended for use in cosmetics and personal care formulations.

Hydrogenated Castor Oil is soluble in both water and oil and is traditionally used to emulsify and solubilize oil-in-water formulations.
Hydrogenated castor oil (HCO) is foam-enhancing properties make it ideal for use in liquid cleansers.
As a surfactant, Hydrogenated castor oil (HCO) helps to decrease the surface tension between multiple liquids or between liquids and solids.

Furthermore, Hydrogenated castor oil (HCO) helps to remove the grease from oils and causes them to become suspended in the liquid.
Hydrogenated castor oil (HCO) is manufactured by adding hydrogen to refined Castor Oil in the presence of a nickel catalyst, the resultant oil is called Hydrogenated Castor Oil.
After filtration, the liquid Hydrogenated castor oil (HCO) goes either to Flaking machine to get Hydrogenated castor oil (HCO) Flakes or to Spray Drying Tower to get HCO Powder.

After filtration Hydrogenated castor oil (HCO) is transformed into a hard, brittle wax with a melting point of approximately 85-86 degrees Centigrade.
This wax is extremely insoluble and is therefore well suited for products needing resistance to water, oils, petroleum and petroleum derivatives.
Hydrogenated castor oil (HCO), also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications.

This makes Hydrogenated castor oil (HCO) extremely valuable in the manufacturing of lubricants and industrial greases.
However, Hydrogenated castor oil (HCO) is soluble in hot solvents.
Hydrogenated castor oil (HCO) also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities.

Hydrogenated castor oil (HCO) is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated castor oil (HCO) is a non-toxic, non-hazardous material.
Hydrogenated castor oil (HCO) is used in manufacturing of greases, but it may also be used in a paper coating for food packaging.

Hydrogenated castor oil (HCO) can be available with several different melting points, or in beaded or powdered form.
Partially Hydrogenated castor oil (HCO) is used in cosmetic formulations such as lipsticks and stick deodorants.
Hydrogenated castor oil (HCO) is often included in cosmetic and skincare products for its emollient properties.

Hydrogenated castor oil (HCO) helps to soften and smooth the skin, providing a moisturizing effect.
Due to its increased viscosity compared to regular castor oil, Hydrogenated castor oil (HCO) is used as a thickening agent in cosmetic and personal care formulations.
Hydrogenated castor oil (HCO) helps give products a desired texture and consistency.

The hydrogenation process makes Hydrogenated castor oil (HCO) more resistant to oxidation, contributing to improved stability.
This makes it suitable for use in formulations where a longer shelf life is desired.
In some cases, Hydrogenated castor oil (HCO) can act as a surfactant. Surfactants help to reduce the surface tension of liquids and are commonly used in formulations like shampoos and cleansers.

Hydrogenated castor oil (HCO)'s lubricating properties make it suitable for certain industrial applications, such as in the production of greases and lubricants.
Hydrogenated castor oil (HCO) may find use in pharmaceutical formulations for its emollient and stabilizing properties.

Density: 0.97g/cm3 at 20℃
vapor pressure: 0Pa at 20℃
solubility: Practically insoluble in water; soluble in acetone, chloroform, and methylene chloride.
form: Powder
Dielectric constant: 10.3(27℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 18.75

Hydrogenated castor oil (HCO) is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps.
To learn more about HCO safety, please review the Hydrogenated castor oil (HCO).
Acme-Hardesty is a reliable source for Hydrogenated castor oil (HCO).

Hydrogenated castor oil (HCO) performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.
Hydrogenated castor oil (HCO) is also useful in the preparation of various polyurethane coating formulas.
Personal Care There are multiple Hydrogenated castor oil (HCO) uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.

Waxes Hydrogenated Caster Oil works as a binding agent in synthetic and petroleum waxes, as it makes the wax harder and more resistant to crumbling.
Soaps and Detergents Hydrogenated castor oil (HCO) is sometimes used as an emulsifying agent in liquid soaps and detergents to enhance the stability of the liquid formula.
Textiles Hydrogenated castor oil (HCO) makes an effective processing agent in various textile manufacturing applications.

Lubricants and Greases Hydrogenated castor oil (HCO) is used as a thickening agent in lithium grease and lithium complex grease, as well as multipurpose greases and metal-drawing lubricants.
Hydrogenated castor oil (HCO), also called Castor Wax, is a hard, brittle, high melting solid which is tasteless and odorless.
Chemically it is the triglyceride mainly of 12-Hydroxy Stearic Acid.

Hydrogenated castor oil (HCO) is insoluble in water and solubility in many organic solvents is also very limited.
Hydrogenated castor oil (HCO) is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated castor oil (HCO) is a non-toxic, non-hazardous material.

Hydrogenated castor oil (HCO) is used in pharmaceutical applications and manufacture of greases and lubricants.
Hydrogenated castor oil (HCO) is used in a range of cosmetics & toiletries.
Hydrogenated castor oil (HCO) or castor wax is a hard, brittle wax.

Hydrogenated castor oil (HCO) is odorless and insoluble in water.
Hydrogenated castor oil (HCO) is produced by addition of hydrogen to castor oil (hydrogenation process) in the presence of a nickel catalyst.
This is done by bubbling Hydrogenated castor oil (HCO) gas into the castor oil, during which the Ricinoleic Acid becomes fully saturated to give a viscous waxy like substance with a melting point of 61-69oC.

Hydrogenated castor oil (HCO) accounts for the largest single use of castor oil for a standard commodity.
The Hydrogenated castor oil (HCO) is insoluble in water and most organic solvents, but it is soluble in hot solvents.
Hydrogenated castor oil (HCO) is water resistant while retaining lubricity, polarity and surface wetting properties.

Hydrogenated castor oil (HCO) is this insolubility that makes HCO valuable to the lubricants markets.
Hydrogenated castor oil (HCO) is perfect for metal drawing lubricants and multipurpose industrial greases.
Hydrogenated castor oil (HCO) is used in polishes, cosmetics, electrical capacitors, carbon paper, lubrication, and coatings and greases where resistance to moisture, oils and petrochemical products is required.

Hydrogenated castor oil (HCO), is a derivative of castor oil that has undergone a hydrogenation process, resulting in changes to its chemical structure and properties.
Hydrogenated castor oil (HCO) is known for its versatility and is used in various industries and applications due to its unique characteristics.
Hydrogenated castor oil (HCO) is obtained from the fruit seed of castor (Ricinus communis L.) a large shrub that grows mainly in India, Brazil and China.

Ricinoleic Acid is the major component of the oil, about 85% The hydrogenated castor oil (HCO) is obtained form castor oil hydrogenation process.
Hydrogenated castor oil (HCO) is a solid at room temperatureand melts above 85 ° C.
Hydrogenated castor oil (HCO) is marketed in the form of flakes or granules, is white and opaque.

Hydrogenated castor oil (HCO) is mainly used in the formulation of lubricants and greases, resins, synthetic waxes, rigid or plasticized films and chemical intermediates.
Hydrogenated castor oil (HCO) has a very high oxidative stability and acts very effectively as an internal and external lubricant in polymers.
This is an oil wit flexibility and ductility for the manufacturer of industrial resins, plastics, elastomers, dielectric, rubber products in general.

Hydrogenated castor oil (HCO) is also used in the cosmetics sector.
Hydrogenated castor oil (HCO) derivatives are produced in India by manufacturers who have worked with Berg + Schmidt for many years.
Special attention is paid to the continuous development of quality standards.

India is already the most important procurement market for Hydrogenated castor oil (HCO), and its significance is steadily growing.
Hydrogenated castor oil (HCO) is passed through Refined castor oil with Nickel as to get Hydrogenated Castor Oil.
After filtration, the liquid HCO goes either to Flaking machine to get Hydrogenated castor oil (HCO) Flakes or to Spray Drying Tower to get HCO Powder.

Hydrogenated castor oil (HCO) is typically insoluble in water but soluble in oil and organic solvents.
This solubility profile can influence its application in different formulations.
Hydrogenated castor oil (HCO) has film-forming properties, making it useful in formulations where the creation of a protective film on the skin or hair is desirable.

This is often seen in cosmetics like lipsticks or hair care products.
Due to its emollient properties and relatively low likelihood of clogging pores, Hydrogenated castor oil (HCO) is often used in skincare products, particularly those designed for individuals with sensitive or acne-prone skin.
In some formulations, especially in the production of shaving creams and foaming personal care products, Hydrogenated castor oil (HCO) may serve as a foaming agent.

Hydrogenated castor oil (HCO) is known for its compatibility with a wide range of cosmetic ingredients, allowing formulators to create stable and well-blended products.
Hydrogenated castor oil (HCO), is a vegetable oil obtained from the castor plant.
This bio-based origin is often valued in the formulation of natural or organic cosmetic products.

While hydrogenation is typically a chemical process, Hydrogenated castor oil (HCO) can be derived from both natural castor oil and synthetic sources.
The choice between natural and synthetic HCO may depend on factors like cost, sustainability, and the desired level of purity in the final product.

Uses:
Hydrogenated castor oil (HCO)s dispersed in base oil to make multipurpose greases having higher dropping points, hardness, better rust-proofing, lubricity and durability than stearates.
Hydrogenated castor oil (HCO) of different melting points used in lipsticks, deodorant and antiperspirant sticks, cosmetic creams.
Hydrogenated castor oil (HCO) is a hard wax with a high melting point used in oral and topical pharmaceutical formulations.

In topical formulations, Hydrogenated castor oil (HCO) is used to provide stiffness to creams and emulsions.
In oral formulations, Hydrogenated castor oil (HCO) is used to prepare sustained-release tablet and capsule preparations; the hydrogenated castor oil may be used as a coat or to form a solid matrix.
Hydrogenated castor oil (HCO), being a hydrogenated form of castor oil, can be a source of stearic acid.

Hydrogenated castor oil (HCO) is used in the production of candles and waxes to enhance their structure and stability.
Hydrogenated castor oil (HCO) can be employed as a plasticizer in the polymer industry, contributing to the flexibility and durability of certain plastic products.
In the food industry, Hydrogenated castor oil (HCO) can be used as a release agent in the production of molds and pans to prevent food from sticking.

Due to its thickening properties, Hydrogenated castor oil (HCO) can act as a viscosity modifier in the formulation of adhesives and sealants, contributing to the desired consistency.
Hydrogenated castor oil (HCO)'s lubricating properties make it suitable for use in metalworking fluids, where it can enhance lubricity and reduce friction in cutting and machining processes.
In the textile industry, Hydrogenated castor oil (HCO) may be used as a softening agent for fabrics, contributing to a softer feel and improved texture.

Hydrogenated castor oil (HCO) can serve as a binder in the formulation of paints and coatings, helping to improve adhesion and durability.
In the rubber industry, Hydrogenated castor oil (HCO) can function as a plasticizer and processing aid, improving the flexibility and processing characteristics of rubber compounds.
Hydrogenated castor oil (HCO)'s emollient properties can be beneficial in the leather industry, where it may be used as a softening agent for leather products.

Hydrogenated castor oil (HCO) can be used in the formulation of environmentally friendly inks and toners, contributing to sustainable printing and imaging solutions.
In lubricants and greases, Hydrogenated castor oil (HCO) may act as a natural and renewable ingredient, providing eco-conscious solutions for machinery and mechanical systems.
Hydrogenated castor oil (HCO) is employed in adhesives and sealants, offering natural and renewable components for eco-friendly bonding solutions.

Hydrogenated castor oil (HCO) can be incorporated into coatings and paints to enhance their performance, sustainability, and eco-friendliness.
Hydrogenated castor oil (HCO) can be used in eco-conscious packaging materials and coatings, promoting sustainability in packaging solutions.
In cosmetics, personal care products, and skincare formulations, hydrogenated castor oil contributes to natural and eco-friendly products.

Hydrogenated castor oil (HCO) may find applications in pharmaceutical formulations and drug delivery systems.
In the tire and rubber industry, hydrogenated castor oil can be employed in rubber compound formulations to enhance processing and performance.
Hydrogenated castor oil (HCO) is used in the formulation of wax blends for various applications, providing eco-friendly alternatives in wax-based products.

Hydrogenated castor oil (HCO) can find applications in eco-friendly cleaning products and household items, contributing to sustainable and natural alternatives.
Hydrogenated castor oil (HCO) may have agricultural applications, such as in crop protection formulations and soil conditioning products, promoting sustainable agricultural practices.
Hydrogenated castor oil (HCO) is a wax used in applications ranging from the manufacture of lithium and calcium greases, hot melts in sealants and coatings, mold release agents for plastic or rubber, paper coats, and personal care.

Hydrogenated castor oil (HCO) is hard and brittle with a high melting point, and is suitable for us as a structurant for antiperspirant sticks or lipstick.
Hydrogenated castor oil (HCO) Ethoxylates have many uses, primarily as nonionic surfactants in various formulations both, industrial & domestic.
These are also used as cleaning agents, antistatic agents, dispersants or emulsifiers, defoamers, softeners in textile formulations.

Also these are used as emulsifiers, solubalizers in cosmetics , health care & agrochemical formulations.
Hydrogenated castor oil (HCO) is commonly used an emulsifiers and co-emulsifiers in lubricants and softener formulas.
Hydrogenated castor oil (HCO) may also be used as a dispersant for pigments and clay.

Hydrogenated castor oil (HCO) is used in cosmetics and personal care products, such as creams, lotions, and lip balms, for its emollient properties.
Hydrogenated castor oil (HCO) helps soften and moisturize the skin.
Hydrogenated castor oil (HCO) is increased viscosity makes it a useful thickening agent in cosmetic formulations, providing the desired texture to products like creams and ointments.

v's stability makes it suitable for stabilizing formulations and extending the shelf life of cosmetic products.
Similar to its use in cosmetics, Hydrogenated castor oil (HCO) may be used in pharmaceutical formulations for its emollient properties and ability to stabilize certain formulations.
Due to its lubricating properties, Hydrogenated castor oil (HCO) is used in the production of industrial lubricants and greases.

In some industrial applications, Hydrogenated castor oil (HCO) may serve as a surfactant to reduce surface tension.
Hydrogenated castor oil (HCO)'s film-forming properties make it suitable for use in hair care products, such as styling gels and creams, where the formation of a protective film on the hair is desired.
In formulations like shaving creams and foaming cleansers, Hydrogenated castor oil (HCO) may act as a foaming agent.

In pharmaceuticals, Hydrogenated castor oil (HCO) can serve as an excipient, helping to improve the texture and stability of certain formulations.
Hydrogenated castor oil (HCO) is bio-based origin from castor oil makes it suitable for use in natural and organic cosmetic and personal care products.

Safety Profile:
Hydrogenated castor oil (HCO) is used in oral and topical pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material.
Acute oral toxicity studies in animals have shown that Hydrogenated castor oil (HCO) is a relatively nontoxic material.
Irritation tests with rabbits show that Hydrogenated castor oil (HCO) causes mild, transient irritation to the eye.

Storage:
Hydrogenated castor oil (HCO) is stable at temperatures up to 1508℃. Clear, stable, chloroform solutions containing up to 15% w/v of hydrogenated castor oil may be produced.
Hydrogenated castor oil (HCO) may also be dissolved at temperatures greater than 908℃ in polar solvents and mixtures of aromatic and polar solvents, although the hydrogenated castor oil precipitates out on cooling below 908℃.
Hydrogenated castor oil (HCO) should be stored in a well-closed container in a cool, dry place.
HYDROGENATED CASTOR OIL 40 ETHOXYLATE

Hydrogenated Castor Oil 40 Ethoxylate, also known by its abbreviation Hydrogenated castor oil 40 ethoxylate, is a nonionic surfactant derived from castor oil.
Hydrogenated castor oil 40 ethoxylate is formed by the reaction between hydrogenated castor oil and ethylene oxide.
The number '40' in its name refers to the degree of ethoxylation, indicating that 40 moles of ethylene oxide have reacted with hydrogenated castor oil.

CAS Number: 61791-12-6



APPLICATIONS


In cosmetic formulations, Hydrogenated castor oil 40 ethoxylate serves as an emulsifier, aiding in the blending of water and oil-based ingredients in creams and lotions.
Hydrogenated castor oil 40 ethoxylate is commonly found in skincare products like moisturizers and serums to stabilize and create well-blended emulsions.

Hydrogenated castor oil 40 ethoxylate plays a significant role in formulating hair care products such as shampoos and conditioners to maintain stability and consistency.
In the production of bath products, it facilitates the uniform dispersion of oils and fragrances.
Its use in sunscreen formulations supports the dispersion of UV filters and active ingredients.
Hydrogenated castor oil 40 ethoxylate finds application in makeup products, ensuring even blending of various components like pigments and oils.

Hydrogenated castor oil 40 ethoxylate aids in the creation of stable and homogeneous blends in deodorants and antiperspirants.
In the pharmaceutical industry, Hydrogenated castor oil 40 ethoxylate is utilized in ointments and creams for its emulsifying and dispersing properties.
Hydrogenated castor oil 40 ethoxylate is instrumental in creating stable and well-dispersed emulsions in wound care products.

Hydrogenated castor oil 40 ethoxylate contributes to the formulation of topical medications, enabling the even distribution of active ingredients.
Its use extends to industrial processes where stable emulsification is required, such as in the production of adhesives.

In textile manufacturing, Hydrogenated castor oil 40 ethoxylate aids in the dispersion of dyes and chemicals in dyeing and finishing processes.
Hydrogenated castor oil 40 ethoxylate is employed in pesticide formulations to enable the proper mixing of active ingredients and additives.

Hydrogenated castor oil 40 ethoxylate contributes to the creation of stable emulsions in agricultural products, such as herbicides and fungicides.
Its application in household cleaning products ensures the effective dispersion and blending of various ingredients.

In the paint and coating industry, it serves as a dispersing agent for pigments and additives.
Hydrogenated castor oil 40 ethoxylate's emulsifying properties are utilized in the formulation of personal care products like body washes and shower gels.
Hydrogenated castor oil 40 ethoxylate aids in the dispersion and blending of fragrances and essential oils in perfumes and colognes.

Hydrogenated castor oil 40 ethoxylate supports the production of pet care products, ensuring the proper dispersion of active ingredients.
In the food industry, Hydrogenated castor oil 40 ethoxylate is employed as an emulsifier in certain food additives and processing aids.
Hydrogenated castor oil 40 ethoxylate is used in the creation of printing inks, ensuring the even dispersion of pigments and additives.

Hydrogenated castor oil 40 ethoxylate aids in the formulation of industrial lubricants, contributing to the proper blending of oil-based components.
Hydrogenated castor oil 40 ethoxylate plays a role in the creation of stable emulsions in metalworking fluids and coolants.
In the creation of agricultural adjuvants, it helps disperse and stabilize active agents in formulations.
Its role in numerous industries highlights its significance in stabilizing, dispersing, and creating homogeneous blends in diverse formulations.

Hydrogenated castor oil 40 ethoxylate is utilized in the formulation of hair styling products, aiding in the even dispersion of active components.
In the production of pet grooming products, it assists in dispersing oils and active ingredients.
Its emulsifying properties are beneficial in the creation of veterinary skincare and wound care products.

Hydrogenated castor oil 40 ethoxylate finds application in the formulation of veterinary shampoos and conditioners, ensuring the proper blending of ingredients.
In the agricultural sector, it supports the production of crop protection products like insecticides and herbicides.
Its dispersing qualities are employed in the creation of crop nutrition formulations, ensuring effective blending.

In the formulation of industrial cleaning products, Hydrogenated castor oil 40 ethoxylate contributes to the even distribution of active components.
Hydrogenated castor oil 40 ethoxylate aids in the creation of adhesive formulations, ensuring stability and proper blending.
Hydrogenated castor oil 40 ethoxylate is used in the formulation of automotive care products, facilitating the even dispersion of active ingredients.
In the creation of lubricants, it helps blend various oil-based components for optimal performance.

Hydrogenated castor oil 40 ethoxylate's emulsifying properties support the creation of printing ink formulations, ensuring proper dispersion.
In the manufacture of leather care products, it assists in creating stable and well-blended emulsions.

Its applications extend to the formulation of metal cleaning and treatment solutions, ensuring effective dispersion.
Hydrogenated castor oil 40 ethoxylate is employed in the creation of wood care products, facilitating proper mixing of active agents.
In the construction industry, it aids in the formulation of concrete additives, ensuring proper blending.

It plays a role in the formulation of sealants and caulks, aiding in the even distribution of components.
Hydrogenated castor oil 40 ethoxylate is utilized in the creation of wax-based polishes, ensuring a well-dispersed and stable product.
In the formulation of polymer additives, it contributes to the proper mixing of active agents.
Its emulsifying properties are beneficial in the creation of foam products for various applications.

Hydrogenated castor oil 40 ethoxylate aids in the formulation of paper and pulp processing aids, ensuring proper dispersion.
In the creation of textile auxiliaries, it supports the blending of different fabric treatment components.

Hydrogenated castor oil 40 ethoxylate plays a role in the formulation of detergent additives, aiding in the even distribution of active ingredients.
Hydrogenated castor oil 40 ethoxylate is utilized in the formulation of personal hygiene products, ensuring effective dispersion of active components.

In the creation of pharmaceutical excipients, it aids in the proper mixing of various components.
Its versatile applications highlight its significance in diverse industries, ensuring proper blending and dispersion in various formulations.

In the production of textile dyes, Hydrogenated castor oil 40 ethoxylate facilitates the dispersion and blending of colorants and additives.
Hydrogenated castor oil 40 ethoxylate is utilized in the formulation of textile softeners, aiding in the even distribution of active components.
Hydrogenated castor oil 40 ethoxylate is instrumental in creating stable emulsions for textile sizing and finishing products.

In the construction sector, it aids in the creation of mortar additives, ensuring proper blending and dispersion.
Hydrogenated castor oil 40 ethoxylate plays a role in the formulation of paint and coating additives, aiding in the even distribution of pigments.
In the production of household paints, Hydrogenated castor oil 40 ethoxylate ensures the proper dispersion of colorants and additives.

Hydrogenated castor oil 40 ethoxylate supports the creation of adhesives for woodworking, ensuring stable and uniform adhesion.
Hydrogenated castor oil 40 ethoxylate's emulsifying properties aid in the formulation of wood treatments and protectants.

Hydrogenated castor oil 40 ethoxylate is utilized in the creation of metalworking fluids, ensuring proper blending and stability.
Hydrogenated castor oil 40 ethoxylate assists in creating stable emulsions for industrial metal cleaners and degreasers.
In the manufacturing of printing inks, it supports the dispersion of pigments and colorants.

Hydrogenated castor oil 40 ethoxylate plays a role in the formulation of resin additives, ensuring the even distribution of active components.
Hydrogenated castor oil 40 ethoxylate supports the production of electronic cleaner formulations, ensuring effective dispersion.
In the creation of photographic chemicals, it aids in the even distribution of sensitive compounds.
Hydrogenated castor oil 40 ethoxylate plays a role in the formulation of film processing solutions, ensuring proper blending of chemicals.

Hydrogenated castor oil 40 ethoxylate contributes to the creation of soldering fluxes, aiding in the even dispersion of active agents.
In the production of industrial cleaning agents, it ensures the proper blending of cleaning components.

Hydrogenated castor oil 40 ethoxylate is used in the creation of industrial degreasers, supporting the even distribution of cleaning agents.
Hydrogenated castor oil 40 ethoxylate facilitates the formulation of metal treatment solutions for corrosion prevention and stability.

Hydrogenated castor oil 40 ethoxylate aids in the creation of corrosion inhibitors for various industrial applications.
In the production of hydraulic fluids, it ensures stable emulsions and proper blending.
Hydrogenated castor oil 40 ethoxylate supports the creation of heat transfer fluids, ensuring stability and effective dispersion.

Hydrogenated castor oil 40 ethoxylate is utilized in the creation of coolant additives for industrial equipment, ensuring proper blending.
Hydrogenated castor oil 40 ethoxylate contributes to the formulation of drilling fluids, supporting stability and proper blending.
Its extensive applications underscore its significance in various industrial processes, ensuring stable and well-blended formulations across a wide array of applications.

In the formulation of rust and corrosion inhibitors for industrial machinery, Hydrogenated castor oil 40 ethoxylate aids in stabilizing and blending the protective agents.
Hydrogenated castor oil 40 ethoxylate plays a role in the creation of industrial surfactants, ensuring proper dispersion and stability in cleaning solutions.

Hydrogenated castor oil 40 ethoxylate is employed in the production of mold release agents for various manufacturing processes, ensuring uniform application.
Hydrogenated castor oil 40 ethoxylate aids in the formulation of polymer additives for enhancing the properties of plastics, ensuring proper blending and dispersion.

In the creation of industrial solvents, it facilitates proper blending of components for effective use.
Hydrogenated castor oil 40 ethoxylate contributes to the production of oilfield chemicals, ensuring the proper mixing of additives for enhanced functionality.
Hydrogenated castor oil 40 ethoxylate supports the creation of adjuvants for agricultural chemicals, ensuring proper dispersion and stability.

In the formulation of drilling muds for geotechnical purposes, Hydrogenated castor oil 40 ethoxylate contributes to stable and well-blended solutions.
Hydrogenated castor oil 40 ethoxylate is utilized in the production of concrete additives, ensuring proper blending and dispersion in construction materials.

Hydrogenated castor oil 40 ethoxylate aids in the creation of soil stabilizers, ensuring uniform dispersion of stabilizing agents.
In the formulation of rubber and tire treatments, Hydrogenated castor oil 40 ethoxylate supports the even blending of enhancing agents.

Hydrogenated castor oil 40 ethoxylate plays a role in the creation of wood preservatives, ensuring proper mixing and stability for effective treatment.
Hydrogenated castor oil 40 ethoxylate is utilized in the formulation of asphalt additives for road construction, ensuring stability and proper blending.
Hydrogenated castor oil 40 ethoxylate contributes to the creation of ink additives for specialized printing applications, ensuring proper dispersion.

In the production of ceramics, Hydrogenated castor oil 40 ethoxylate aids in creating stable emulsions and well-mixed solutions for glazes.
Hydrogenated castor oil 40 ethoxylate supports the creation of battery additives, ensuring the proper dispersion of active components.
Hydrogenated castor oil 40 ethoxylate is utilized in the formulation of fire-resistant compounds, ensuring proper blending and stability in applications.

In the creation of gas treatment chemicals, it supports the dispersion and even mixing of treatment agents.
Hydrogenated castor oil 40 ethoxylate contributes to the formulation of desiccants for moisture control in various industrial processes.

Hydrogenated castor oil 40 ethoxylate aids in the creation of sealant additives, ensuring proper blending and dispersion in sealant solutions.
Hydrogenated castor oil 40 ethoxylate plays a role in the formulation of industrial gels and thickeners, ensuring proper viscosity and stability.
In the production of lubricant additives for heavy machinery, it ensures proper blending and stability.

Hydrogenated castor oil 40 ethoxylate contributes to the formulation of insulation materials, ensuring stable and well-blended solutions.
Hydrogenated castor oil 40 ethoxylate supports the creation of cooling agent additives for refrigeration systems, ensuring effective dispersion.
Its wide-ranging applications highlight its significance in ensuring stable, well-blended formulations across diverse industrial processes.



DESCRIPTION


Hydrogenated Castor Oil 40 Ethoxylate, also known by its abbreviation Hydrogenated castor oil 40 ethoxylate, is a nonionic surfactant derived from castor oil.
Hydrogenated castor oil 40 ethoxylate is formed by the reaction between hydrogenated castor oil and ethylene oxide.
The number '40' in its name refers to the degree of ethoxylation, indicating that 40 moles of ethylene oxide have reacted with hydrogenated castor oil.

Hydrogenated Castor Oil 40 Ethoxylate, known as Hydrogenated castor oil 40 ethoxylate, is a nonionic surfactant derived from castor oil.
Hydrogenated castor oil 40 ethoxylate is produced through the ethoxylation of hydrogenated castor oil with around 40 moles of ethylene oxide.

This process gives Hydrogenated castor oil 40 ethoxylate its surfactant properties, making it an effective emulsifier and dispersant.
Its emulsifying action facilitates the blending of oil and water-based substances in various formulations.

Hydrogenated castor oil 40 ethoxylate possesses an HLB value around 14-16, making it more lipophilic and suitable for oil-in-water emulsions.
As a nonionic surfactant, Hydrogenated castor oil 40 ethoxylate is versatile and compatible with various surfactants, oils, and waxes.
Hydrogenated castor oil 40 ethoxylate plays a significant role in stabilizing emulsions and maintaining the integrity of formulations.

In skincare products, Hydrogenated castor oil 40 ethoxylate contributes to creating stable and well-blended emulsions in lotions and creams.
Its emulsifying capabilities extend to hair care products such as shampoos and conditioners.
Hydrogenated castor oil 40 ethoxylate's surfactant properties aid in wetting agents, supporting the even spread of liquids in various applications.

Hydrogenated castor oil 40 ethoxylate acts as a dispersing agent, promoting the even distribution of substances within a mixture.
Due to its emulsifying properties, it finds use in both cosmetic and industrial applications.

Hydrogenated castor oil 40 ethoxylate acts as a thickening agent in certain formulations, enhancing viscosity and texture.
Its stability in different environments makes it ideal for various cosmetic and pharmaceutical formulations.
Hydrogenated castor oil 40 ethoxylate helps achieve the desired texture and stability in a range of consumer products.

Its nonionic nature means it is less likely to cause skin irritation, making it suitable for sensitive skin products.
Hydrogenated castor oil 40 ethoxylate is often found in ointments, creams, and topical pharmaceutical preparations.
In industrial settings, it plays a crucial role in processes that require stable emulsification.

Its compatibility with different ingredients allows for diverse formulations in cosmetic and industrial products.
Hydrogenated castor oil 40 ethoxylate's ability to enhance the texture and stability of formulations makes it a popular choice in the industry.
Hydrogenated castor oil 40 ethoxylate's versatility allows it to serve various roles in the formulation of cosmetic and personal care items.

Its emulsifying and stabilizing properties support the overall quality of formulated products.
Hydrogenated castor oil 40 ethoxylate is instrumental in maintaining the consistency and stability of numerous consumer goods.
Its surfactant properties ensure proper dispersion and blending of ingredients in various formulations.
Hydrogenated castor oil 40 ethoxylate's contribution to creating well-mixed and stable products makes it a valuable ingredient in numerous applications.



PROPERTIES


Physical Properties:

Appearance: Typically a waxy solid or liquid, which might depend on the ambient temperature.
Color: Ranges from pale yellow to colorless, depending on its purity and processing.
Odor: Generally odorless or with a faint, characteristic odor.
Solubility: Hydrogenated castor oil 40 ethoxylate is soluble in water, alcohol, and many organic solvents.
Density: Varies according to its form and temperature.
Melting Point/Freezing Point: Depends on the exact composition, but it typically solidifies at lower temperatures.


Surface-Active Properties:

Surfactant: Acts as a nonionic surfactant, having emulsifying and dispersing properties.
Wetting Agent: Exhibits wetting properties, aiding in the even spreading of liquids.
Emulsifying Agent: Effective in forming stable emulsions of oil and water-based substances.
Dispersing Agent: Assists in the even dispersion of substances within a medium.



FIRST AID


Inhalation:

If inhaled and respiratory discomfort occurs, move the affected person to a well-ventilated area for fresh air.
If breathing difficulties persist, seek medical attention.


Skin Contact:

In case of contact with the skin, remove contaminated clothing and wash the affected area thoroughly with soap and water.
If skin irritation develops or persists, seek medical advice.


Eye Contact:

In case of contact with the eyes, immediately rinse with plenty of water for at least 15 minutes while keeping eyelids open.
If irritation persists or there is discomfort, seek medical attention.


Ingestion:

If ingested accidentally and the exposed individual is conscious, rinse the mouth and drink plenty of water.
Seek medical advice and provide details about the substance ingested.


General Measures:

Always consult the safety data sheet (SDS) or product label for specific first aid instructions.
If any symptoms persist or worsen, seek medical attention.
Be prepared to provide information about the substance involved to healthcare professionals.



HANDLING AND STORAGE


Handling:

Personal Protection:
Use appropriate personal protective equipment (PPE) such as gloves and safety goggles when handling Hydrogenated castor oil 40 ethoxylate to prevent direct skin or eye contact.

Ventilation:
Work in a well-ventilated area to minimize inhalation of vapor or dust, if applicable.

Avoid Skin Contact:
In case of contact, wash the affected skin area thoroughly with soap and water.

Avoid Inhalation:
Use masks or protective gear to prevent inhalation of any aerosols or vapors, especially in powdered forms.

Labeling:
Ensure proper labeling of containers to avoid confusion with other substances and always keep safety data sheets accessible.


Storage:

Controlled Environment:
Store Hydrogenated castor oil 40 ethoxylate in a cool, dry area away from direct sunlight to maintain stability and quality.

Temperature:
Avoid exposure to extreme temperatures as they might affect the composition and properties of the compound.

Sealed Containers:
Use tightly sealed containers to prevent moisture absorption and ensure the integrity of the product.

Segregation:
Store away from incompatible substances to prevent reactions or contamination.

Compliance:
Follow local regulations and guidelines for storing chemical substances.


Specific Recommendations:

Handling Procedures:
Follow standard handling procedures, such as avoiding unnecessary exposure and spills.

Re-Sealing:
Close containers tightly after use to prevent moisture from compromising the compound.

Avoid Oxidizing Agents:
Keep away from strong oxidizing agents that might react with Hydrogenated castor oil 40 ethoxylate.



SYNONYMS


Hydrogenated castor oil 40 ethoxylate
Ethoxylated Hydrogenated Castor Oil
Ethoxylated Castor Oil
Hydrogenated Castor Oil Ethoxylate
Polyethylene Glycol Hydrogenated Castor Oil
Castorwax
Cremophor® RH 40
Emcol Hydrogenated castor oil 40 ethoxylate
Nikkol Hydrogenated castor oil 40 ethoxylate
PEG-HCO
Croduret® 40
Castor Oil Ethoxylate
Eumulgin® HRE 40
Lutrol® E 400
Macrogol Hydrogenated Castor Oil
Atlas G-1153
Admul P-40
Javachem Hydrogenated castor oil 40 ethoxylate
Polyoxyl Hydrogenated Castor Oil
Polyoxyethylene (40) Castor Oil
Surfonol® 104 H
Alkox® E-40
Pearlitol® Hydrogenated castor oil 40 ethoxylate
Sovermol® 105
Emanon® 310P
HYDROGENATED CASTOR OIL ETHOXYLATE
Hydrogenated Castor Oil Ethoxylate Hydrogenated castor oil ethoxylate, also known as castor wax, is a hardened vegetable wax produced from pure Hydrogenated castor oil ethoxylate through the chemical process of hydrogenation. When hydrogen is introduced to pure Hydrogenated castor oil ethoxylate in the presence of a nickel catalyst, the resulting product becomes waxy, highly viscous, and more saturated.Hydrogenated castor oil ethoxylate is an ingredient prevalently found in many cosmetics, varnishes, and polishes. You most likely use it on a daily basis. Unlike pure Hydrogenated castor oil ethoxylate, which is said to have a slightly offensive smell, it is completely odorless. Hydrogenated castor oil ethoxylate is also insoluble in water.But why hydrogenate Hydrogenated castor oil ethoxylate when the pure oil works so well for so many different applications? What is the purpose of hydrogenating Hydrogenated castor oil ethoxylate, exactly? ydrogenated Hydrogenated castor oil ethoxylate, also known as castor wax, is derived from castor beans (Ricinus communis), which is typically a liquid at room temperature, that has been processed by adding hydrogen to make it more stable and raises its melting point so that it is a solid at room temperature. It is odorless and insoluble in water. Historically, ancient Egyptians used Hydrogenated castor oil ethoxylate as fuel for their lamps. Hydrogenated castor oil ethoxylate has also been used as a lubricant in machine and aircraft engines, and is added to certain paints, dyes and varnishes as well. Ingestion of pure Hydrogenated castor oil ethoxylate works as a laxative to treat constipation. Hydrogenated castor oil ethoxylate is a hard brittle, high melting point waxy substance with faint characteristic of fatty wax odor and is tasteless. It is compatible with beeswax, carnauba and candelilla wax. It is relatively insoluble in most organic solvents though it will dissolve in a number of solvents and oils at an elevated temperature but on cooling will form gels or a paste like mass. It forms a smooth, stable anionic emulsion with emulsifiers and triethanolamine stearate. It can also be emulsified with a cationic emulsifying agent, making emulsions that are also stable. It is mainly used in plastics, textiles, lubricants etc.As a pharmaceutical grade inactive ingredient, Hydrogenated castor oil ethoxylate is used to emulsify and solubilize oils and other water-insoluble substances. Identification CAS no. 61788-85-0 Label EC no. Value 500-147-5 Label Molecul formula Value C57H110O9 (C2H4O)n Label REACH status Value 01-2120775815-41 Label Synonyms Value Castor oil, hydrogenated, ethoxylated Label E-number / INCI name Value N.A. / PEG-n HYDROGENATED CASTOR OIL A brand name product that contains Hydrogenated castor oil ethoxylate is Cremophor and it contains a range of non-ionic polyethoxylated detergents. It was originally developed for use as solubilizers and emulsifiers. This research grade product is intended for use in R&D and development only. Hydrogenated castor oil ethoxylate (castor wax) is also used an extended release agent; stiffening agent; tablet and capsule lubricant. Hydrogenated castor oil ethoxylate has been used as a stimulant laxative to relieve occasional constipation, but it is rarely used today due to gentler and safer alternatives. The purpose of the hydrogenation process is to improve Hydrogenated castor oil ethoxylate's melting point, texture, odor, and shelf-life.Once hydrogenated, the resulting Hydrogenated castor oil ethoxylate product is comprised of hard, brittle flakes. Hydrogenated castor oil ethoxylate is considered an organic ingredient, as well as a vegan one, as it is vegetable-derived.One application of Hydrogenated castor oil ethoxylate is to improve certain cosmetic products. You can add the flakes to cosmetic formulations until thoroughly melted. In this capacity, Hydrogenated castor oil ethoxylate acts as an emollient and a thickener; increasing the viscosity of creams, ointments, and lotions when their composition is too runny. Hydrogenated castor oil ethoxylate also stabilizes cosmetics that come in stick-form (like lipstick) and increases these products' melting points, making for a more stable product. In part thanks to Hydrogenated castor oil ethoxylate, it's not the end of the world if we leave a tube of red lipstick in a hot car! Hydrogenated castor oil ethoxylate means our lipsticks maintain a solid structure even when they're pushed to the limit, and our deodorant doesn't crumble as we apply it.Hydrogenated castor oil ethoxylate is a hard, waxy substance with a unique structure. It works with the other oils and waxes in the antiperspirant base to give the stick a firm but spreadable consistency. In the baby diaper cream and lotion it provides a protective barrier of the lotion/cream on the skin. In all cases, because Hydrogenated castor oil ethoxylate is insoluble in water, it is not readily washed away. Hydrogenated castor oil ethoxylate is especially present in these types of products when something requires resistance to moisture and oils, such as in polishes, varnishes, and paints. Hydrogenated castor oil ethoxylate, also known as castor wax, is derived from castor beans (Ricinus communis), which is typically a liquid at room temperature, that has been processed by adding hydrogen to make it more stable and raises its melting point so that it is a solid at room temperature. It is odorless and insoluble in water. Hydrogenated castor oil ethoxylate is a hard, waxy substance with a unique structure. It works with the other oils and waxes in the antiperspirant base to give the stick a firm but spreadable consistency. In all cases, because Hydrogenated castor oil ethoxylate is insoluble in water, it is not readily washed away. Hydrogenated castor oil ethoxylate has a long history of safe use in personal care products. PEG 40 Hydrogenated castor oil ethoxylate is the Polyethylene Glycol derivatives of Hydrogenated castor oil ethoxylate, and it functions as a surfactant, a solubilizer, an emulsifier, an emollient, a cleansing agent, and a fragrance ingredient when added to cosmetics or personal care product formulations. Hydrogenated castor oil ethoxylate is soluble in both water and oil and is traditionally used to emulsify and solubilize oil-in-water formulations. Its foam-enhancing properties make it ideal for use in liquid cleansers, and its soothing and softening emollient quality makes it a popular addition to formulations for moisturizers and hair care cosmetics. As a surfactant, PEG 40 Hydrogenated castor oil ethoxylate helps to decrease the surface tension between multiple liquids or between liquids and solids. Furthermore, it helps to remove the grease from oils and causes them to become suspended in the liquid. This makes it easier for them to be washed away and lends this ingredient popularity in facial and body cleansers. As an occlusive agent, PEG 40 Hydrogenated castor oil ethoxylate creates a protective hydrating layer on the skin's surface, acting as a barrier against the loss of natural moisture. Hydrogenated castor oil ethoxylate to cosmetics formulations, it can be blended in its cold state directly into the oil phase at a suggested ratio of 3:1 (PEG 40 Hydrogenated castor oil ethoxylate to oil). Next, this can be added to the water phase. If the formula is cloudy, the amount of PEG 40 Hydrogenated castor oil ethoxylate may be increased for enhanced transparency. Hydrogenated castor oil ethoxylate Raw Material without the medical advice of a physician. This product should always be stored in an area that is inaccessible to children, especially those under the age of 7. Hydrogenated castor oil ethoxylate Raw Material in 1 tsp of a preferred Carrier Oil and applying a dime-size amount of this blend to a small area of skin that is not sensitive. PEG 40 Hydrogenated castor oil ethoxylate must never be used near the inner nose and ears or on any other particularly sensitive areas of skin. Potential side effects of PEG 40 Hydrogenated castor oil ethoxylate include the itching, PEG-30 Hydrogenated castor oil ethoxylate, PEG-33 Hydrogenated castor oil ethoxylate, PEG-35 Hydrogenated castor oil ethoxylate, PEG-36 Hydrogenated castor oil ethoxylate and PEG-40 Hydrogenated castor oil ethoxylate are polyethylene glycol derivatives of Hydrogenated castor oil ethoxylate. PEG-30 Hydrogenated castor oil ethoxylate and PEG-40 Hydrogenated castor oil ethoxylate are polyethylene glycol derivatives of Hydrogenated castor oil ethoxylate. PEG-36 Hydrogenated castor oil ethoxylate is a light yellow and slightly viscous liquid with a mild fatty odor. PEG-40 Hydrogenated castor oil ethoxylate is an amber-colored liquid. PEG Hydrogenated castor oil ethoxylates and PEG Hydrogenated castor oil ethoxylates are used in the formulation of a wide variety of cosmetics and personal care products. Hydrogenated castor oil ethoxylate is the polyethylene glycol derivatives of Hydrogenated castor oil ethoxylate, and is an amber colored, slightly viscous liquid that has a naturally mildly fatty odor. It is used in cosmetics and beauty products as an emulsifier, surfactant, and fragrance ingredient, according to research. Accordingly, Hydrogenated castor oil ethoxylate is principally 12-hydroxystearic triglyceride. Hydrogenated castor oil ethoxylate (HCO) or castor wax is used in capacitors, coatings and greases, cosmetics, electrical carbon paper, lubrication, polishes, and where resistance to moisture, oils and other petrochemical products is required. Castor wax is also useful as a top coat varnish for leather, wood & rubber. 12-Hydroxy Stearic Acid (12-HSA) is obtained by the hydrolysis of Hydrogenated castor oil ethoxylate, 12-Hydroxy Stearic Acid is a high melting, brittle, waxy solid at ambient temperatures and should be stored away from heat to avoid deterioration. A non-toxic, non-hazardous material, it has limited solubility in many organic solvents and is insoluble in water. It is used in lithium and calcium greases, and in the manufacture of acrylic polymers, as an internal lubricant for plastic mouldings, coatings for automotive, equipment, appliances and architectural applications. We are proud to boast industry leading products suitable for a wide array of application and product requirements. We believe industry leading customer service, delivery and innovation allow us to meet our ever increasing client demands. Hydrogenated castor oil ethoxylate is a wax-like hydrogenated derivative of Hydrogenated castor oil ethoxylate. Hydrogenated castor oil ethoxylate has many industrial applications. Castor wax, also called Hydrogenated castor oil ethoxylate, is an opaque, white vegetable wax. It is produced by the hydrogenation of pure Hydrogenated castor oil ethoxylate often in the presence of a nickel catalyst to increase the rate of reaction. The hydrogenation of Hydrogenated castor oil ethoxylate forms saturated molecules of castor wax; this saturation is responsible for the hard, brittle and insoluble nature of the wax. HCO (chemical name: Hydrogenated castor oil ethoxylate), also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications. What is Hydrogenated castor oil ethoxylate? HCO is a hard, wax-like substance extracted from Hydrogenated castor oil ethoxylate beans. There is also a petroleum-based formula of Hydrogenated Caster Oil known as PEG-40. The Hydrogenated castor oil ethoxylate chemical formula of this material is C57H110O9(CH2CH2O)n. Hydrogenation refers to a chemical process where an unsaturated compound is combined with hydrogen to produce saturation. In the case of HCO, this increases the oil’s stability and raises its melting point, transforming it into a solid at room temperature.Hydrogenated castor oil ethoxylate is insoluble in water and most types of organic solvents. This makes HCO extremely valuable in the manufacturing of lubricants and industrial greases. However, HCO is soluble in hot solvents. It also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities. Hydrogenated castor oil ethoxylate is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps. To learn more about HCO safety, please review the Hydrogenated castor oil ethoxylate SDS (Safety Data Sheet).Acme-Hardesty is a reliable source for Hydrogenated castor oil ethoxylate. We offer a complete selection of Hydrogenated castor oil ethoxylate and Derivatives such as Ricinoleic Acid, 12HSA, #1 Hydrogenated castor oil ethoxylate, HCO and several others. We are known for being one of the largest and oldest Hydrogenated castor oil ethoxylate importers and distributors found anywhere in the United States. As one of the leading Hydrogenated castor oil ethoxylate suppliers, we can accommodate your company’s Hydrogenated castor oil ethoxylate needs, whether you require a bulk shipment, a pallet or a full truckload. USES & APPLICATIONS HCO is an extremely versatile oleochemical that has a number of industrial and manufacturing applications:CASE: Because of its excellent resistance to moisture, Hydrogenated castor oil ethoxylate works extremely well as a viscosity modifier, and it also provides significant improvement in grease and oil resistance.Plastics: Hydrogenated castor oil ethoxylate performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene. It is also useful in the preparation of various polyurethane coating formulas.Personal Care: There are multiple Hydrogenated castor oil ethoxylate uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.Waxes: Hydrogenated Caster Oil works as a binding agent in synthetic and petroleum waxes, as it makes the wax harder and more resistant to crumbling.Soaps and Detergents: Hydrogenated castor oil ethoxylate is sometimes used as an emulsifying agent in liquid soaps and detergents to enhance the stability of the liquid formula.Textiles: HCO makes an effective processing agent in various textile manufacturing applications. What does it do? Hydrogenated castor oil ethoxylate is a hard, waxy substance with a unique structure. It works with the other oils and waxes in the antiperspirant base to give the stick a firm but spreadable consistency. In all cases, because Hydrogenated castor oil ethoxylate is insoluble in water, it is not readily washed away. In monolithic tablets, the core is either prepared by direct compression or by wet granulation followed by coating the core with water impermeable materials on all the faces except the face which is in contact with the mucosa. Water-impermeable materials include Teflon, ethyl cellulose, cellophane, Hydrogenated castor oil ethoxylate, and so on. Such a system begins unidirectional drug flow toward the mucosa and avoids drug loss [163]. The results of Kurihara et al. (1996) indicate that Hydrogenated castor oil ethoxylate (HCO)-60 emulsions, when compared with conventional lecithin-stabilized emulsions, are more stable to LPL and show low uptake by RES organs, long circulations in the plasma and high distribution in tumors. Lin et al. (1992) confirmed that Hydrogenated castor oil ethoxylate-60 is a good emulsifier for the preparation of NE with better stability and prolonged and selective delivery properties. Thus, these sterically stabilized NEs could show potential as effective carriers for highly lipophilic antitumor agents to enhance the drug delivery in tumors. This was confirmed by Sakaeda et al. (1994) who found that the rate of selective delivery of Sudan II to liver, lungs, and spleen could be suppressed by using Hydrogenated castor oil ethoxylate-60-based NE. Conversely, the use of saturated MCT in NE was the most effective way to increase blood concentration of Sudan II, resulting in higher distribution to liver, lungs, spleen, and brain (Sakaeda and Hirano, 1995). Furthermore, an o/w-type NE containing Hydrogenated castor oil ethoxylate-60 was shown to be superior in the selective distribution of adriamycin-HCl to the liver and in decreasing concentration in heart and kidney (Yamaguchi et al., 1995). Again, Ueda et al. (2003) reported the effect of using a series of Hydrogenated castor oil ethoxylates having different oxyethylene numbers such as Hydrogenated castor oil ethoxylate10, Hydrogenated castor oil ethoxylate 20, Hydrogenated castor oil ethoxylate 30, Hydrogenated castor oil ethoxylate 60, and Hydrogenated castor oil ethoxylate 100 on the pharmacokinetics of menatetrenone (vitamin K2) incorporated in SO (SO)–based NE in rats. Plasma half-life of menatetrenone after administration as the NE prepared by Hydrogenated castor oil ethoxylate with 10 oxyethylene units (SO/Hydrogenated castor oil ethoxylate 10) was similar to that after the administration as SO/egg yolk phosphatides (SO/EYP), but was shorter than that as the NEs prepared by Hydrogenated castor oil ethoxylates with >20 oxyethylene units (SO/Hydrogenated castor oil ethoxylate 20, SO/Hydrogenated castor oil ethoxylate 30, SO/Hydrogenated castor oil ethoxylate 60, and SO/Hydrogenated castor oil ethoxylate 100). These findings clearly demonstrate that 20 oxyethylene units in Hydrogenated castor oil ethoxylates are the minimum requirement for the prolongation of the plasma circulation time of the incorporated drug in SO/Hydrogenated castor oil ethoxylates NEs. The earlier described studies suggest the involvement of oil or structured lipids in the enhancement of systemic circulation of the NE. Hydrogenated castor oil ethoxylate is a multi-purpose vegetable oil that people have used for thousands of years. It’s made by extracting oil from the seeds of the Ricinus communis plant. These seeds, which are known as castor beans, contain a toxic enzyme called ricin. However, the heating process that Hydrogenated castor oil ethoxylate undergoes deactivates it, allowing the oil to be used safely. Hydrogenated castor oil ethoxylate has a number of medicinal, industrial and pharmaceutical uses. It’s commonly used as an additive in foods, medications and skin care products, as well as an industrial lubricant and biodiesel fuel component. In ancient Egypt, Hydrogenated castor oil ethoxylate was burned as fuel in lamps, used as a natural remedy to treat ailments like eye irritation and even given to pregnant women to stimulate labor. Today, Hydrogenated castor oil ethoxylate remains a popular natural treatment for common conditions like constipation and skin ailments and is commonly used in natural beauty products. Here are 7 benefits and uses of Hydrogenated castor oil ethoxylate. 1. A Powerful Laxative Perhaps one of the best-known medicinal uses for Hydrogenated castor oil ethoxylate is as a natural laxative. It’s classified as a stimulant laxative, meaning that it increases the movement of the muscles that push material through the intestines, helping clear the bowels. Stimulant laxatives act rapidly and are commonly used to relieve temporary constipation. When consumed by mouth, Hydrogenated castor oil ethoxylate is broken down in the small intestine, releasing ricinoleic acid, the main fatty acid in Hydrogenated castor oil ethoxylate. The ricinoleic acid is then absorbed by the intestine, stimulating a strong laxative effect. In fact, several studies have shown that Hydrogenated castor oil ethoxylate can relieve constipation. For example, one study found that when elderly people took Hydrogenated castor oil ethoxylate, they experienced decreased symptoms of constipation, including less straining during defecation and lower reported feelings of incomplete bowel movements. While Hydrogenated castor oil ethoxylate is considered safe in small doses, larger amounts can cause abdominal cramping, nausea, vomiting and diarrhea (4Trusted Source). Although it can be used to relieve occasional constipation, Hydrogenated castor oil ethoxylate is not recommended as a treatment for long-term issues. Hydrogenated castor oil ethoxylate can be used as a natural remedy for occasional constipation. However, it can cause side effects like cramping and diarrhea and should not be used to treat chronic constipation. 2. A Natural Moisturizer Hydrogenated castor oil ethoxylate is rich in ricinoleic acid, a monounsaturated fatty acid. These types of fats act as humectants and can be used to moisturize the skin. Humectants retain moisture by preventing water loss through the outer layer of the skin. Hydrogenated castor oil ethoxylate is often used in cosmetics to promote hydration and often added to products like lotions, makeup and cleansers. You can also use this rich oil on its own as a natural alternative to store-bought moisturizers and lotions. Many popular moisturizing products found in stores contain potentially harmful ingredients like preservatives, perfumes and dyes, which could irritate the skin and harm overall health. Swapping out these products for Hydrogenated castor oil ethoxylate can help reduce your exposure to these additives. Plus, Hydrogenated castor oil ethoxylate is inexpensive and can be used on the face and body. Hydrogenated castor oil ethoxylate is thick, so it’s frequently mixed with other skin-friendly oils like almond, olive and coconut oil to make an ultra-hydrating moisturizer. Though applying Hydrogenated castor oil ethoxylate to the skin is considered safe for most, it can cause an allergic reaction in some people (6Trusted Source). Hydrogenated castor oil ethoxylate can help lock moisture in the skin. Though this natural alternative to store-bought products is considered safe for most, it can cause allergic reactions in some. 3. Promotes Wound Healing Applying Hydrogenated castor oil ethoxylate to wounds creates a moist environment that promotes healing and prevents sores from drying out. Venelex, a popular ointment used in clinical settings to treat wounds, contains a mixture of Hydrogenated castor oil ethoxylate and Peru balsam, a balm derived from the Myroxylon tree. Hydrogenated castor oil ethoxylate stimulates tissue growth so that a barrier can be formed between the wound and the environment, decreasing the risk of infection. It also reduces dryness and cornification, the buildup of dead skin cells that can delay wound healing (8). Studies have found that ointments containing Hydrogenated castor oil ethoxylate may be especially helpful in healing pressure ulcers, a type wound that develops from prolonged pressure on the skin. One study looked at the wound-healing effects of an ointment containing Hydrogenated castor oil ethoxylate in 861 nursing home residents with pressure ulcers. Those whose wounds were treated with Hydrogenated castor oil ethoxylate experienced higher healing rates and shorter healing times than those treated with other methods (9Trusted Source). Hydrogenated castor oil ethoxylate helps heal wounds by stimulating the growth of new tissue, reducing dryness and preventing the buildup of dead skin cells. 4. Impressive Anti-Inflammatory Effects Ricinoleic acid, the main fatty acid found in Hydrogenated castor oil ethoxylate, has impressive anti-inflammatory properties. Studies have shown that when Hydrogenated castor oil ethoxylate is applied topically, it reduces inflammation and relieves pain. The pain-reducing and anti-inflammatory qualities of Hydrogenated castor oil ethoxylate may be particularly helpful to those with an inflammatory disease such as rheumatoid arthritis or psoriasis. Animal and test-tube studies have found that ricinoleic acid reduces pain and swelling. One study demonstrated that treatment with a gel containing ricinoleic acid led to a significant reduction in pain and inflammation when applied to the skin, compared to other treatment methods. A test-tube component of the same study showed that ricinoleic acid helped reduce inflammation caused by human rheumatoid arthritis cells more than another treatment. Aside from Hydrogenated castor oil ethoxylate’s potential to reduce inflammation, it may help relieve dry, irritated skin in those with psoriasis, thanks to its moisturizing properties. Although these results are promising, more human studies are needed to determine the effects of Hydrogenated castor oil ethoxylate on inflammatory conditions. Hydrogenated castor oil ethoxylate is high in ricinoleic acid, a fatty acid that has been shown to help reduce pain and inflammation in test-tube and animal studies. 5. Reduces Acne Acne is a skin condition that can cause blackheads, pus-filled pimples and large, painful bumps on the face and body. It’s most common in teens and young adults and can negatively impact self-esteem. Hydrogenated castor oil ethoxylate has several qualities that may help reduce acne symptoms. Inflammation is thought to be a factor in the development and severity of acne, so applying Hydrogenated castor oil ethoxylate to the skin may help reduce inflammation-related symptoms. Acne is also associated with an imbalance of certain types of bacteria normally found on the skin, including Staphylococcus aureus. Hydrogenated castor oil ethoxylate has antimicrobial properties that may help fight bacterial overgrowth when applied to the skin. One test-tube study found that Hydrogenated castor oil ethoxylate extract showed considerable antibacterial power, inhibiting the growth of several bacteria, including Staphylococcus aureus. Hydrogenated castor oil ethoxylate is also a natural moisturizer, so it may help soothe the inflamed and irritated skin typical in those with acne. Hydrogenated castor oil ethoxylate helps fight inflammation, reduce bacteria and soothe irritated skin, all of which can be helpful for those looking for a natural acne remedy. 6. Fights Fungus Candida albicans is a type of fungus that commonly causes dental issues like plaque overgrowth, gum infections and root canal infections. Hydrogenated castor oil ethoxylate has antifungal properties and may help fight off Candida, keeping the mouth healthy. One test-tube study found that Hydrogenated castor oil ethoxylate eliminated Candida albicans from contaminated human tooth roots. Hydrogenated castor oil ethoxylate may also help treat denture-related stomatitis, a painful condition thought to be caused by Candida overgrowth. This is a common issue in elderly people who wear dentures. A study in 30 elderly people with denture-related stomatitis showed that treatment with Hydrogenated castor oil ethoxylate led to improvements in the clinical signs of stomatitis, including inflammation (17Trusted Source). Another study found that brushing with and soaking dentures in a solution containing Hydrogenated castor oil ethoxylate led to significant reductions in Candida in elderly people who wore dentures (18Trusted Source). Several studies have shown that Hydrogenated castor oil ethoxylate may help fight fungal infections in the mouth caused by Candida albicans. 7. Keeps Your Hair and Scalp Healthy Many people use Hydrogenated castor oil ethoxylate as a natural hair conditioner. Dry or damaged hair can especially benefit from an intense moisturizer like Hydrogenated castor oil ethoxylate. Applying fats like Hydrogenated castor oil ethoxylate to the hair on a regular basis helps lubricate the hair shaft, increasing flexibility and decreasing the chance of breakage. Hydrogenated castor oil ethoxylate may benefit those who experience dandruff, a common scalp condition characterized by dry, flaky skin on the head. Though there are many different causes of dandruff, it has been linked to seborrhoeic dermatitis, an inflammatory skin condition that causes red, scaly patches on the scalp. Due to Hydrogenated castor oil ethoxylate’s ability to reduce inflammation, it may be an effective treatment for dandruff that is caused by seborrhoeic dermatitis. Plus, applying Hydrogenated castor oil ethoxylate to the scalp will help moisturize dry, irritated skin and may help reduce flaking. The moisturizing and anti-inflammatory properties of Hydrogenated castor oil ethoxylate make it an excellent option to keep hair soft and hydrated and help reduce dandruff symptoms. Hydrogenated castor oil ethoxylate Precautions Many people use Hydrogenated castor oil ethoxylate to treat a variety of issues, either by ingesting the oil or applying it to the skin. Although Hydrogenated castor oil ethoxylate is generally considered safe, it can cause adverse reactions and unwanted side effects in some people. Can induce labor: It’s used by medical professionals to induce birth. For this reason, women at all stages of pregnancy should avoid consuming Hydrogenated castor oil ethoxylate. Can cause diarrhea: While it can be an effective way to alleviate constipation, you may get diarrhea if you take too much. Diarrhea can cause dehydration and electrolyte imbalances. Can cause allergic reactions: It may cause an allergic reaction in some people when applied to the skin. First try applying a small amount to a tiny patch of skin to see how your body reacts. Hydrogenated castor oil ethoxylate can cause side effects, such as allergic reactions and diarrhea, in some people. It can also induce labor, so pregnant women should avoid it. The Bottom Line People have used Hydrogenated castor oil ethoxylate for thousands of years as a powerful natural treatment for a variety of health issues. It has been shown to help relieve constipation and moisturize dry skin, among many other uses. If you are searching for an affordable, multi-purpose oil to keep in your medicine cabinet, Hydrogenated castor oil ethoxylate may be a good choice. Dehydrated Hydrogenated castor oil ethoxylate is an unique drying oil, which imparts good flexibility, fine gloss, toughness, adhesion, chemical and water resistance to the dry paint film with non-yellowing properties. Hydrogenated castor oil ethoxylate is a very suitable and even better substitute for Linseed oil. Paints with Hydrogenated castor oil ethoxylate are super white and offer superior finish. Dehydrated Hydrogenated castor oil ethoxylate is used as a primary binder for house paints, enamels, caulks, sealants and inks. In “cooked” varnishes it is combined with all the basic resins, rosins, rosin-esters, hydrocarbons and phenolics to produce clear varnishes and vehicles for pigmented coatings. Hydrogenated castor oil ethoxylate is also used in the manufacturing of lithographic inks, linoleum, putty and phenolic resins. Hydrogenated castor oil ethoxylate is used with phenolics to obtain fast drying coatings with maximum alkali resistance as required in sanitary can lining, corrosion resistant coatings, traffic paints, varnishes, ink vehicles, wire enamels, aluminium paint appliance finishes and marine finishes. Hydrogenated castor oil ethoxylate is also used to obtain fast kettling rate which gives lighter colour and lower acid varnishes. Hydrogenated castor oil ethoxylate is a release and antisticking agent used in hard candy pro- duction. its concentration is not to exceed 500 ppm. it is used in vitamin and mineral tablets, and as a component of protective coatings. Hydrogenated castor oil ethoxylate is a highly emollient carrier oil that penetrates the skin easily, leaving it soft and supple. It also serves to bind the different ingredients of a cosmetic formulation together. Hydrogenated castor oil ethoxylate is high in glycerin esters of ricinoleic acid (an unsaturated fatty acid). It is rarely, if ever, associated with irritation of the skin or allergic reactions. It is obtained through cold-pressing from seeds or beans of the Ricinus communis (Hydrogenated castor oil ethoxylate) plant. Impure Hydrogenated castor oil ethoxylate may cause irritation, as the seeds contain a toxic substance that is eliminated during processing. Its unpleasant odor makes it difficult to use in cosmetics. PEG-30 Hydrogenated castor oil ethoxylate, -30 Hydrogenated castor oil ethoxylate (hydrogenated), -40 Hydrogenated castor oil ethoxylate, -40 Hydrogenated castor oil ethoxylate (hydrogenated) are emollients, detergents, emulsifiers, and oil-in-water solubilizers recommended for fragrance oils, and for other oils that may be difficult to solubilize. The -40 Hydrogenated castor oil ethoxylate version is a powerful solubilizer for solubilizing essential oils and perfumes in oil-in-water creams
HYDROGENATED CASTOR OIL FLAKE
Hydrogenated castor oil flake, also called Castor Wax, is a hard, brittle, high melting solid which is tasteless and odourless.
Chemically Hydrogenated castor oil flake is the triglyceride, which mainly consists of 12-Hydroxy Stearic Acid.
Hydrogenated castor oil flake is insoluble in water and solubility in many organic solvents is also very limited.

CAS: 8001-78-3
EINECS: 232-292-2

Synonyms
OPAL WAX;PEG 60;PEG 40;CASTOR OIL HYDROGENATED;CASTOR WAX;CELLO-GREASE LUBRICANT;CELLO-SEAL LUBRICANT;HYDROGENATED CASTOR OIL;Hydrogenated Castor Oil;8001-78-3;Castor Oil, Hydrogenated;232-292-2;Castor Wax;Castor oil hydrogenated;Castorwax;ZF94AP8MEY;1,2,3-Propanetriol tri(12-hydroxystearate);12-Hydroxyoctadecanoic acid, 1,2,3-propanetriyl ester;CASTOR OIL, HYDROGENATED (EP IMPURITY);CASTOR OIL, HYDROGENATED (EP MONOGRAPH);CASTOR OIL,HYDROGENATED;Castorwax MP-70;Castorwax MP-80;Castorwax NF;Caswell No. 486A;DTXSID8027666;EC 232-292-2;EINECS 232-292-2;EPA Pesticide Chemical Code 031604;HYDROGENATED CASTOR OIL (II);HYDROGENATED CASTOR OIL (USP-RS);LUBLIWAX;OPALWAX;Olio di ricino idrogenato;Rice syn wax;UNII-ZF94AP8MEY;Unitina HR

Hydrogenated castor oil flake is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated castor oil flake is a hard product with a high melting point.
Hydrogenated castor oil flake is almost odourless and tasteless.
Hydrogenated castor oil flake is supplied in flakes and powder.
Hydrogenated castor oil flake is cream to white coloured.
Hydrogenated castor oil flake is a wax used in applications ranging from manufacture of lithium and calcium greases, hot melts in sealants and coatings, mold release agents for plastic or rubber, paper coats, and personal care.

Hydrogenated castor oil flake is hard and brittle with high melting point, and is suitable for us as a structurant for antiperspirant sticks or lipstick.
Hydrogenated castor oil flake is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated castor oil flake is a non-toxic, non-hazardous material.
Hydrogenated castor oil flake is used in pharmaceutical applications, manufacture of greases and lubricants, and range of cosmetics & toiletries.
Castor Oil becomes HHydrogenated castor oil flake, a hard, brittle wax with a melting point of about 85 to 86 degrees Celsius, when hydrogen is added to it in the presence of a nickel catalyst.
Hydrogenated castor oil flakes are a non-hazardous and non-toxic product that, when melted, transform into a clear, transparent liquid.

Hydrogenated castor oil flake is a powerful occlusive agent that not only hydrates the skin and hair but also creates a protective barrier to prevent moisture loss.
Also known as castor wax, Hydrogenated castor oil flake appears in the form of a white-yellow solid, flakes, or powder.
Hydrogenated castor oil flake is the more stable form of castor oil that has a high melting point.
Hydrogenated castor oil flake is widely used in personal care products due to its varied benefits ranging from hydrating and soothing the skin to binding and controlling the viscosity of formulations.
Hydrogenated castor oil flake is also an excellent anti-aging ingredient.
The chemical formula of Hydrogenated castor oil flake is C57H110O9.
Hydrogenated castor oil flake is a versatile ingredient for a number of applications.
Also called castor wax, Hydrogenated castor oil flake is a hard, brittle vegetable wax produced from the hydrogenation of castor oil.
Hydrogenated castor oil flake is available in powder or flake form.
Hydrogenated castor oil flake is used in lithium greases, lithium complex greases, and as a thickening agent.

Hydrogenated castor oil flake Chemical Properties
Density: 0.97g/cm3 at 20℃
Vapor pressure: 0Pa at 20℃
Solubility: Practically insoluble in water; soluble in acetone, chloroform, and methylene chloride.
Form: Powder
Dielectric constant: 10.3(27℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 18.75
EPA Substance Registry System: Hydrogenated castor oil flake (8001-78-3)

Hydrogenated castor oil flake occurs as a fine, almost white or pale yellow powder or flakes.
The PhEur 6.0 describes Hydrogenated castor oil flake as the oil obtained by hydrogenation of virgin castor oil.
Hydrogenated castor oil flake consists mainly of the triglyceride of 12-hydroxystearic acid.
Hydrogenated castor oil flake — also called HCO or castor wax — is a hard, white, opaque vegetable wax.
Hydrogenated castor oil flake's resistance to moisture makes it useful in many coatings, greases, cosmetics, polishes and similar applications.
Hydrogenated castor oil flake is created by hydrogenating pure liquid castor oil, which is obtained from castor beans.
Hydrogenated castor oil flake is heated under extreme pressure using a nickel catalyst during the hydrogenation process.
Afterward, the hydrogen creates saturated molecules of castor wax, which gives the oil a higher melting point that allows it to remain solid at room temperature.
After hydrogenation, Hydrogenated castor oil flake becomes hard and brittle to the touch.

Uses
Greases: Lithium- and Calcium hydroxystearates dispersed in base oil to make multipurpose greases having higher dropping points, hardness, better rust-proofing, lubricity and durability than stearates.
Other lubricants: metal drawing lubes, PVC lubricants for PVC pipes, profiles, sheets, pharma tabletting, metal powders, ceramics.
Cosmetics: Hydrogenated castor oil flake of different melting points used in lipsticks, deodorant and antiperspirant sticks, cosmetic creams.
slip additive in inks, paints, plastics (PE).
dispersing agent in plastic colour master batches, carbon papers, inks.
flow control and dispersing additive in powder coatings, hot-melt adhesives and sealants.
shoe polishing, furniture polishing creams.

Pharmaceutical Applications
Hydrogenated castor oil flake is a hard wax with a high melting point used in oral and topical pharmaceutical formulations.
In topical formulations, Hydrogenated castor oil flake is used to provide stiffness to creams and emulsions.
In oral formulations, Hydrogenated castor oil flake is used to prepare sustained-release tablet and capsule preparations; the hydrogenated castor oil may be used as a coat or to form a solid matrix.
Hydrogenated castor oil flake is additionally used to lubricate the die walls of tablet presses; and is similarly used as a lubricant in food processing.
Hydrogenated castor oil flake is also used in cosmetics.

Hydrogenated Castor Oil Flakes is incredibly insoluble, making it ideal for items that need to be resistant to water, oils, petroleum, and petroleum derivatives.
In addition to being used to make greases, Hydrogenated castor oil flake can be used to coat paper used to package food.
Hydrogenated castor oil flake can be found in powdered or beaded form, or with a variety of melting degrees.
Due to its distinct combination of physico-chemical qualities, Hydrogenated castor oil flake has a wide range of diversified uses.
Hydrogenated castor oil flake serves as a mold release agent for processing plastics and rubber as well as in the production of soaps and cosmetics.
Additionally cosmetic products like stick deodorants and lipsticks, also utilize partially hydrogenated castor oil flakes.
Hydrogenated castor oil flake is a wax-like solid at room temperature.
Hydrogenated castor oil flake is derived from Castor Oil (extracted from the seeds of "Ricinus communis L.") by controlled hydrogenation.
Hydrogenated castor oil flake is produced in form of flakes and powder.

Hydrogenated castor oil flake is widely used in the production of multi-purpose calcium and lithium lubricating greases.
Lubricating greases produced from Hydrogenated castor oil flake exhibit excellent resistances to oils and fats, water and solvents and they endue a long-life stability.
Hydrogenated castor oil flake also is importand as thixotropic agent or as raw material in the production thereof for solvent-based coating systems.
Other technical application fields are the use as processing aid for phenolic resins, polyethylene, PVC and rubber and as additive in the application of powder coatings.
Non-drying alkyd resins can also be produced out of Hydrogenated castor oil flake.
Hydrogenated castor oil flake is of importance concerning the production of hot melts like paper coatings for food packaging and the production of hot melt adhesives.
In several types of polishes (for cars, shoes, furniture) Hydrogenated castor oil flake is an ingredient.
Another important field is the use of Hydrogenated castor oil flake and its derivatives (e. g. ethoxylated HCO) in cosmetics like creams, lipsticks etc..
HYDROGENATED CASTOR OIL POWDER
Hydrogenated castor oil powder is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated castor oil powder is a hard product with a high melting point.
Hydrogenated castor oil powder is almost odourless and tasteless.

CAS: 8001-78-3
EINECS: 232-292-2

Synonyms
OPAL WAX;PEG 60;PEG 40;CASTOR OIL HYDROGENATED;CASTOR WAX;CELLO-GREASE LUBRICANT;CELLO-SEAL LUBRICANT;HYDROGENATED CASTOR OIL;Hydrogenated Castor Oil;8001-78-3;Castor Oil, Hydrogenated;232-292-2;Castor Wax;Castor oil hydrogenated;Castorwax;ZF94AP8MEY;1,2,3-Propanetriol tri(12-hydroxystearate);12-Hydroxyoctadecanoic acid, 1,2,3-propanetriyl ester;CASTOR OIL, HYDROGENATED (EP IMPURITY);CASTOR OIL, HYDROGENATED (EP MONOGRAPH);CASTOR OIL,HYDROGENATED;Castorwax MP-70;Castorwax MP-80;Castorwax NF;Caswell No. 486A;DTXSID8027666;EC 232-292-2;EINECS 232-292-2;EPA Pesticide Chemical Code 031604;HYDROGENATED CASTOR OIL (II);HYDROGENATED CASTOR OIL (USP-RS);LUBLIWAX;OPALWAX;Olio di ricino idrogenato;Rice syn wax;UNII-ZF94AP8MEY;Unitina HR

Hydrogenated castor oil powderHydrogenated castor oil is cream to white coloured.
Hydrogenated castor oil powder is stable at temperatures up to 1508℃.
Clear, stable, chloroform solutions containing up to 15% w/v of hydrogenated castor oil may be produced.
Hydrogenated castor oil powder may also be dissolved at temperatures greater than 908℃ in polar solvents and mixtures of aromatic and polar solvents, although the hydrogenated castor oil precipitates out on cooling below 908℃.
Hydrogenated castor oil should be stored in a well-closed container in a cool, dry place.

Hydrogenated castor oil powder is a hydrogenated form of castor oil that is insoluble in water.
Hydrogenated castor oil powder has been used as an antimicrobial agent for various detergent compositions, pharmaceutical preparations, and topical formulations.
Hydrogenated castor oil powder has also been used as a polymerization aid for the production of insoluble polymers, including polyurethane elastomers.
The hydrogenation process changes the chemical composition by increasing the number of hydroxyl groups and reducing the number of unsaturated bonds.
These changes can affect how the molecule interacts with other molecules and its solubility in water.
Low energy activation energies have been reported for Hydrogenated castor oil powder compared to other oils such as olive or sunflower oils.

Hydrogenated castor oil powder is a white, odorless fat obtained by the hydrogenation of castor oil.
Hydrogenated castor oil powder has very good compatibility with natural waxes.
Hydrogenated castor oil powder is mostly used in the manufacture of calcium and lithium lubricating greases.
These lubricating greases exhibit excellent resistance to oils and fats, water and solvents.
Hydrogenated castor oil powder is also used as raw materi-al for solvent based coating systems, for alkyd resins and as processing aid for phenolic resins, poly-ethylene, PVC and rubber and as an additive in powder coatings.
Hydrogenated castor oil powder is also of importance concerning the production of hot melts like paper additives.
Finally Hydrogenated castor oil powder can be used as an ingredient in polishes (for cars, shoes, furniture) and in cosmetics (for creams, lipsticks,…).

Hydrogenated castor oil powder, also known as Castor Wax, is derived from castor beans.
Hydrogenated castor oil powder undergoes a process known as hydrogenation, which involves adding hydrogen to make it solid at room temperature.
Hydrogenated castor oil powder’s a white, waxy substance entirely devoid of smell or taste.
Within the realm of cosmetics, Hydrogenated castor oil powder serves several functions.
Hydrogenated castor oil powder’s primarily used as a skin conditioner, an emollient, and a surfactant.

Hydrogenated castor oil Chemical Properties
Density: 0.97g/cm3 at 20℃
Vapor pressure: 0Pa at 20℃
Solubility: Practically insoluble in water; soluble in acetone, chloroform, and methylene chloride.
Form: Powder
Dielectric constant: 10.3(27℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 18.75
EPA Substance Registry System: Hydrogenated castor oil powder

Hydrogenated castor oil powder is a solid at room temperature and is insoluble in water.
Hydrogenated castor oil powder’s a white, waxy substance entirely devoid of smell or taste . Within the realm of cosmetics, Hydrogenated Castor Oil serves several functions.
Hydrogenated castor oil powder’s primarily used as a skin conditioner, an emollient, and a surfactant.
Hydrogenated castor oil powder occurs as a fine, almost white or pale yellow powder or flakes.
The PhEur 6.0 describes Hydrogenated castor oil powder as the oil obtained by hydrogenation of virgin castor oil.
Hydrogenated castor oil powder consists mainly of the triglyceride of 12-hydroxystearic acid.
Hydrogenated castor oil powder— also called HCO or castor wax — is a hard, white, opaque vegetable wax.

Hydrogenated castor oil powder's resistance to moisture makes it useful in many coatings, greases, cosmetics, polishes and similar applications.
The wax is created by hydrogenating pure liquid castor oil, which is obtained from castor beans.
Hydrogenated castor oil powder is heated under extreme pressure using a nickel catalyst during the hydrogenation process.
Afterward, the hydrogen creates saturated molecules of castor wax, which gives the oil a higher melting point that allows Hydrogenated castor oil powder to remain solid at room temperature.
After hydrogenation, Hydrogenated castor oil powder becomes hard and brittle to the touch.

Uses
Greases: Lithium- and Calcium hydroxystearates dispersed in base oil to make multipurpose greases having higher dropping points, hardness, better rust-proofing, lubricity and durability than stearates.
Other lubricants: metal drawing lubes, PVC lubricants for PVC pipes, profiles, sheets, pharma tabletting, metal powders, ceramics.
Cosmetics: HCO of different melting points used in lipsticks, deodorant and antiperspirant sticks, cosmetic creams.
slip additive in inks, paints, plastics (PE).
dispersing agent in plastic colour master batches, carbon papers, inks.
Flow control and dispersing additive in powder coatings, hot-melt adhesives and sealants.
shoe polishing, furniture polishing creams.

Hydrogenated castor oil powder is a wax used in applications ranging from the manufacture of lithium and calcium greases, hot melts in sealants and coatings, mold release agents for plastic or rubber, paper coats, and personal care.
Hydrogenated castor oil powder is hard and brittle with a high melting point, and is suitable for us as a structurant for antiperspirant sticks or lipstick.

Pharmaceutical Applications
Hydrogenated castor oil powder is a hard wax with a high melting point used in oral and topical pharmaceutical formulations.
In topical formulations, Hydrogenated castor oil powder is used to provide stiffness to creams and emulsions.
In oral formulations, Hydrogenated castor oil powder is used to prepare sustained-release tablet and capsule preparations; the Hydrogenated castor oil powder may be used as a coat or to form a solid matrix.
Hydrogenated castor oil powder is additionally used to lubricate the die walls of tablet presses; and is similarly used as a lubricant in food processing.
Hydrogenated castor oil powder is also used in cosmetics.

Production Methods
Hydrogenated castor oil powder is prepared by the hydrogenation of castor oil using a catalyst.
HYDROGENATED CASTOR OIL POWDER
Hydrogenated Castor Oil Powder is a non-hazardous as well as non-toxic product.
Hydrogenated Castor Oil Powder is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated Castor Oil Powder is white to light yellow powder, lumps or flakes.


CAS Number: 8001-78-3
EC Number: 232-292-2
E-number / INCI name: N.A. / HYDROGENATED CASTOR OIL
Molecul formula: C57H110O9



SYNONYMS:
Cutina HR, Hydrogenated Castor Oil, Unitina HR, Castorwax, Castorwax MP 70, Castorwax MP 80, Croduret, Fancol, ricini oleum hydrogenatum, PEG 60, PEG 40, OPAL WAX, Unitina HR, Rice syn wax, UNII-ZF94AP8MEY, Trihydroxystearin, CELLO-SEAL LUBRICANT, CELLO-GREASE LUBRICANT, Olio di ricino idrogenato, Glyceryl tri(12-hydroxystearate), EPA Pesticide Chemical Code 031604, 1,2,3-Propanetriol tri(12-hydroxystearate), 12-Hydroxyoctadecanoic acid, 1,2,3-propanetriyl ester, Hydrogenated Castor Oil, PEG 40, CASTOR WAX, CASTOR OIL HYDROGENATED, hydrogenated castor oil flakes, Thixcin, Namlon T 206, Kolliwax HCO, PEG 40 CASTOR OIL HYDROGENATED, WNN 1, PEG 60,



Hydrogenated Castor Oil Powder is prepared by hydrogenation of castor oil, and its main component is 12-hydroxystearic acid triglyceride.
Hydrogenated Castor Oil Powder is white to light yellow powder, lumps or flakes.
Hydrogenated Castor Oil Powder is slightly soluble in methylene chloride, insoluble in petroleum ether, very slightly soluble in ethanol, insoluble in water.


Hydrogenated Castor Oil Powder is a white to slightly yellowish, fine, free-flowing powder.
Hydrogenated Castor Oil Powder is a hard, brittle, high melting solid which is tasteless and odourless.
Chemically Hydrogenated Castor Oil Powder is the triglyceride, which mainly consists of 12-Hydroxy Stearic Acid.


Hydrogenated Castor Oil Powder is insoluble in water and solubility in many organic solvents is also very limited.
Hydrogenated Castor Oil Powder is available as flakes or powder which melts to a clear transparent liquid.
Hydrogenated Castor Oil Powder is a non-toxic, non-hazardous material.


Hydrogenated Castor Oil Powder commercial packaging includes a transport friendly and secure box with primary electrostatically dissipative PE packaging material.
Hydrogenated Castor Oil Powder is hard, brittle, solid castor wax which has a high melting point.


Available in wax, powder, or flakes, Hydrogenated Castor Oil Powder is derived after the safe hydrogenation process of refined castor oil.
Hydrogenated Castor Oil Powder is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.
Hydrogenated Castor Oil Powder is insoluble in water, limited solubility in the solvents, high applicability, stability and high-drop point.


Hydrogenated Castor Oil Powder is hard, brittle, solid castor wax which has a high melting point.
Hydrogenated Castor Oil Powder is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.
Hydrogenated Castor Oil (HCO) is meticulously crafted through the hydrogenation process of Castor Oil, employing a Nickel catalyst at elevated temperatures.


This transformation results in a substance often referred
Hydrogenated Castor Oil Powder emerges as a white, crystalline solid in the form of flakes, distinguished by its unique physicochemical properties.
Hydrogenated Castor Oil Powder's production involves a precise chemical alteration, enhancing its versatility and making it a sought-after industrial material.


Hydrogenated Castor Oil Powder, known for its excellent stability and texture, finds widespread applications across various industries.
Its diverse uses stem from the distinctive combination of properties it possesses, making it a valuable ingredient in formulations ranging from cosmetics to industrial products.


Hydrogenated Castor Oil Powder is a wax-like compound obtained by controlled hydrogenation of refined Castor Oil.
Hydrogenated Castor Oil Powder is a hard, brittle, high melting point product that is practically odorless and tasteless.
Hydrogenated Castor Oil Powder is supplied in the form of flakes.


The Color of Hydrogenated Castor Oil Powder is cream to white.
Hydrogenated Castor Oil Powder is solid castor powder of high-melting-point.
Hydrogenated Castor Oil Powder is safely derived after the process of hydrogenation of refined castor oil.


Hydrogenated Castor Oil Powder is a non-hazardous as well as non-toxic product.
Hydrogenated Castor Oil Powder is insoluble in water and has limited solubility in the solvents.
Hydrogenated Castor Oil Powder is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.


Hydrogenated Castor Oil Powder is insoluble in water, limited solubility in the solvents, high applicability, stability and high-drop point.
Hydrogenated Castor Oil Powder is hard, brittle, solid castor wax which has a high-melting-point.
Hydrogenated Castor Oil Powder is derived after the safe hydrogenation process of refined castor oil.


Hydrogenated Castor Oil Powder is a non-toxic, non-hazardous product which when melts turns into a clear transparent liquid.
Hydrogenated Castor Oil Powder is insoluble in water, limited solubility in the solvents, high applicability, stability and high-drop point.
Hydrogenated Castor Oil Powder is a white to slightly yellowish fine free-flowing powder


In topical formulations, Hydrogenated Castor Oil Powder is used to provide stiffness to creams and emulsions.
In oral formulations, Hydrogenated Castor Oil Powder is used to prepare sustained-release tablet and capsule preparations.
Hydrogenated Castor Oil Powder is also known as Synthetic Wax.


Hydrogenated Castor Oil Powder is white crystalline solid flakes.
Hydrogenated Castor Oil Powder finds a number of diversified uses due to its unique combination of physic-chemical properties.
Hydrogenated Castor Oil Powder is a hard, brittle, solid castor wax with a high melting point.


Derived through a safe hydrogenation process from refined castor oil, Hydrogenated Castor Oil Powder is available in the form of wax, powder, or flakes.
Hydrogenated Castor Oil Powder is known for its excellent stability, high-drop point, and limited solubility in solvents.
Hydrogenated Castor Oil Powder is a non-toxic and non-hazardous product that transforms into a clear transparent liquid when melted.


Hydrogenated Castor Oil Powder has excellent viscosity-modifying properties, making it ideal for improving grease and oil resistance.
Hydrogenated Castor Oil Powder is a hard, brittle, solid castor wax derived through a safe hydrogenation process.
Hydrogenated Castor Oil Powder has a high melting point and is available in the form of wax, powder, or flakes.


Hydrogenated Castor Oil Powder is insoluble in water and possesses excellent stability, high-drop point, and limited solubility in solvents.
Also known as castor wax, Hydrogenated Castor Oil Powder appears in the form of a white-yellow solid, flakes, or powder.
Hydrogenated Castor Oil Powder is cream to white coloured.


Hydrogenated Castor Oil Powder is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated Castor Oil Powder is a hard product with a high melting point.
Hydrogenated Castor Oil Powder is almost odourless and tasteless.


Hydrogenated Castor Oil Powder is supplied in flakes and powder.
Hydrogenated Castor Oil Powder is cream to white coloured.
Hydrogenated Castor Oil Powder is a compound attained by the hydrogenation of refined castor oil.


Hydrogenated Castor Oil Powder is a hard, waxy, white to cream colored product with a high melting point of 83 to 87 C°, and is nearly tasteless and odorless.
Hydrogenated Castor Oil Powder is a wax like compound obtained by the controlled hydrogenation of refined Castor Oil.


Hydrogenated Castor Oil Powder is a hard, brittle, high melting point product that is practically odourless and tasteless.
Hydrogenated Castor Oil Powder is supplied in the form of flakes or as powder.
The colour of Hydrogenated Castor Oil Powder is cream to white.


When melted Hydrogenated Castor Oil Powder is clear, transparent to straw coloured.
Hydrogenated Castor Oil Powder, also known as castor wax, is a very common oleochemical product that has many industrial and manufacturing applications.
Hydrogenated Castor Oil Powder is a hard, wax-like substance extracted from castor oil beans.


There is also a petroleum-based formula of Hydrogenated Castor Oil Powder known as PEG-40.
Hydrogenated Castor Oil Powder chemical formula of this material is C57H110O9(CH2CH2O)n.
Hydrogenation refers to a chemical process where an unsaturated compound is combined with hydrogen to produce saturation.


In the case of Hydrogenated Castor Oil Powder, this increases the oil’s stability and raises its melting point, transforming it into a solid at room temperature.
Hydrogenated Castor Oil Powder is insoluble in water and most types of organic solvents.


This makes Hydrogenated Castor Oil Powder extremely valuable in the manufacturing of lubricants and industrial greases.
However, Hydrogenated Castor Oil Powder is soluble in hot solvents.
Hydrogenated Castor Oil Powder also has the ability to resist water while retaining its polarity, lubricity and surface wetting capabilities.


Hydrogenated Castor Oil Powder is also an extremely safe, non-toxic material that is suitable for use in personal care products and soaps.
Hydrogenated Castor Oil Powder is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated Castor Oil Powder is a hard product with a high melting point.


Hydrogenated Castor Oil Powder is almost odourless and tasteless, supplied in flakes and powder.
Hydrogenated Castor Oil Powder is a ricinoleic acid that is fully saturated and is similar to a viscous wax-like product with a high melting point.
Hydrogenated Castor Oil Powder is insoluble in most organic solvents, but soluble in hot solvents.


Hydrogenated Castor Oil Powder is a wax-like solid at room temperature.
Hydrogenated Castor Oil Powder is derived from Castor Oil (extracted from the seeds of "Ricinus communis L.") by controlled hydrogenation.
Hydrogenated Castor Oil Powder is produced in form of flakes and powder.


Hydrogenated Castor Oil Powder is a waxy compound obtained by the hydrogenation of refined castor oil.
Hydrogenated Castor Oil Powder is a hard product with a high melting point.
Hydrogenated Castor Oil Powder is almost odourless and tasteless.


Hydrogenated Castor Oil Powder is supplied in flakes and powder. Hydrogenated castor oil is cream to white coloured.
Hydrogenated Castor Oil Powder is a white to creamish flakes or powder.
The melting point of Hydrogenated Castor Oil Powder is°C 83 - 87


Hydrogenated Castor Oil Powder is produced by hydrogenation of castor oil.
Hydrogenated Castor Oil Powder is a versatile integrant for various applications.
As castor oil reduces atmospheric moisture pick-up during handling and mixing, Hydrogenated Castor Oil Powder becomes an essential additive agent for substantial applications.


Hydrogenated Castor Oil Powder is odourless and is available in wax, powder, or flake form with high-melting-point.
These different forms are used as a viscosity modifier and for improvement in grease and oil resistance.
Hydrogenated Castor Oil Powder in cosmetics is a popular addition as it is soluble in both water and oil and has foam-enhancing properties.


Therefore one can easily find Hydrogenated Castor Oil Powder in skincare products like moisturizers as well as hair care cosmetics.
Hydrogenated Castor Oil Powder is a powerful occlusive agent that not only hydrates the skin and hair but also creates a protective barrier to prevent moisture loss.


Also known as castor wax, Hydrogenated Castor Oil Powder appears in the form of a white-yellow solid, flakes, or powder.
Hydrogenated Castor Oil Powder is the more stable form of castor oil that has a high melting point.
Hydrogenated Castor Oil Powder is widely used in personal care products due to its varied benefits ranging from hydrating and soothing the skin to binding and controlling the viscosity of formulations.


Hydrogenated Castor Oil Powder is also an excellent anti-aging ingredient.
The chemical formula of Hydrogenated Castor Oil Powder is C57H110O9.
Hydrogenated Castor Oil Powder is a Hard, Brittle Wax.


Hydrogenated Castor Oil Powder is Produced By Adding Hydrogen to Castor Oil in the Presence of a Nickel Catalyst. in the Hydrogenation Process, the Ricinoleic Acid Becomes Fully Saturated and Forms a Viscous Wax-like Product with a High Melting Point of 86°c.
Hydrogenation May Be Defined as the Conversion of Various Unsaturated Radicals of Fatty Glycerides Into More Highly or Completely Saturated Glycerides By the Addition of Hydrogen in the Presence of a Catalyst.


Hydrogenated oils are Created By a Controlled Heat Process in Which the Melting Point is Raised to Change the Oil Into a Waxy Substance.
The Hydrogenation Process Improves the Stability and Texture of a Product and is Heat Controlled to Avoid the Creation of Trans-fats.
The Object of the Hydrogenation is Not Only to Raise the Melting Point But also to Improve the Keeping Qualities, Taste, and Odor.


Hydrogenated Castor Oil Powder is produced by hydrogenation of Ricinus communis (Castor) seed oil.
Hydrogenated Castor Oil Powder or castor wax is a hard, brittle wax.
Hydrogenated Castor Oil Powder is odorless and insoluble in water.


Hydrogenated Castor Oil Powder is produced by addition of hydrogen to castor oil (hydrogenation process) in the presence of a nickel catalyst.
Hydrogenated Castor Oil Powder is supplied in the form of flakes or as powder.


This is done by bubbling hydrogen gas into the castor oil, during which the Ricinoleic Acid becomes fully saturated to give a viscous waxy like substance with a melting point of 61-69oC.
Hydrogenation of castor oil accounts for the largest single use of castor oil for a standard commodity.


The Hydrogenated Castor Oil Powder is insoluble in water and most organic solvents, but it is soluble in hot solvents.
Hydrogenated Castor Oil Powder is water resistant while retaining lubricity, polarity and surface wetting properties.
Hydrogenated Castor Oil Powder, commonly abbreviated as HCO, is a derivative of castor oil that has undergone a hydrogenation process, resulting in changes to its chemical structure and properties.


Hydrogenated Castor Oil Powder is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Hydrogenated Castor Oil Powder is a hydrogenated form of castor oil that is insoluble in water.


The hydrogenation process changes the chemical composition by increasing the number of hydroxyl groups and reducing the number of unsaturated bonds.
These changes can affect how the molecule interacts with other molecules and Hydrogenated Castor Oil Powder's solubility in water.
Low energy activation energies have been reported for hydrogenated castor oil compared to other oils such as olive or sunflower oils.



USES and APPLICATIONS of HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is used as a thickener, emulsifier in cosmetics.
Hydrogenated Castor Oil Powder is used in ointments as well as fragrances.
Hydrogenated Castor Oil Powder is used manufacturing of candles, lipsticks and crayons


Hydrogenated Castor Oil Powder is used as a viscosity modifier to improve the grease and oil resistance.
The dispersal level of Hydrogenated Castor Oil Powder is good in powder coatings, hot-melt adhesives, elastomer, sealants etc.
Hydrogenated Castor Oil Powder is accessible with high-drop point, high applicability and good stability.


Hydrogenated Castor Oil Powder is used as the viscosity modifier, made to improve resistance against grease and oil.
Hydrogenated Castor Oil Powder has specific dispersal level that ensures its good use in the powder coatings, elastomer, hot-melt adhesives others.
Hydrogenated Castor Oil Powder is used for the production of daily cosmetics, shoe polish, pharmaceutical ointment, is the raw material for the preparation of 12-hydroxy stearic acid.


Hydrogenated Castor Oil Powder is used as a viscosity modifier to improve the grease and oil resistance.
The dispersal level of Hydrogenated Castor Oil Powder is good in powder coatings, hot-melt adhesives, elastomer, sealants etc.
Hydrogenated Castor Oil Powder is used Hot-melt adhesive in packaging, Bookbinding, Footwear, Carpet back, Product Assembly, Thick film chlorinated rubber, Epoxy and vinyl coating, Personal care and cosmetic industries, and Micronized Hydrogenated Castor Oil Powder derivative.


Hydrogenated Castor Oil Powder is used as a viscosity modifier to improve grease and oil resistance.
The dispersal level of Hydrogenated Castor Oil Powder is good in powder coatings, hot-melt adhesives, elastomers, sealants, etc.
As Hydrogenated Castor Oil Powder suppliers, we follow strict protocols to ensure that only the best quality product reaches our customers.


Hydrogenated Castor Oil Powder is used in pharmaceutical applications, manufacture of greases and lubricants, and range of cosmetics & toiletries.
Hydrogenated Castor Oil Powder is hydrogenated castor powder for pharmaceutical application used as consistency factor in topical formulations, as lipohphillic lubricant in tablets and capsules and as plasticizer in solid dispersions using spray drying, melt granulation or hot melt extrusion processes.


Hydrogenated Castor Oil Powder is particularily suitable for formulation of sensitive APIs.
Hydrogenated Castor Oil Powder complies with IPEC GMP standards for critical pharmaceutical applications.
Hydrogenated Castor Oil Powder is used as a consistency factor in topical formulations, as alipophillic lubricant in tablets and capsules, and as a plasticizer in solid dispersions using spray drying, melt granulation or hot melt extrusion processes.


Hydrogenated Castor Oil Powder ensures risk reduction in pharmaceutical applications and meets all relevant regulatory needs.
Hydrogenated Castor Oil Powder is used as retardation component and pressing agent for the preparation of tablets for pharmaceutical application.
Hydrogenated Castor Oil Powder is used for all skin care applications, particularly for sticks.


Hydrogenated Castor Oil Powder is an extremely versatile oleochemical that has a number of industrial and manufacturing applications: Viscosity Modifier, Plastics, Waxes, Personal Care, Soap, Detergent, Textiles, Lubricants and Greases.
Hydrogenated Castor Oil Powder performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.


It is also useful in the preparation of various polyurethane coating formulas.here are multiple Hydrogenated Castor Oil Powder uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.
This versatile ingredient, Hydrogenated Castor Oil Powder, finds applications in various industries due to its exceptional properties.


Hydrogenated Castor Oil Powder is widely used in powder coatings, hot-melt adhesives, elastomers, and sealants.
Hydrogenated Castor Oil Powder is used in a variety of industrial applications.


Hydrogenated Castor Oil Powder is utilized in the production of greases, lubricants, and adhesives to improve their resistance to grease and oil.
Hydrogenated Castor Oil Powder is also used in rubber, plastic, polishes, and coatings to enhance their performance and durability.
Its high-drop point and stable nature make Hydrogenated Castor Oil Powder ideal for applications that require resistance to heat and chemicals.


Hydrogenated castor oil has been used as an antimicrobial agent for various detergent compositions, pharmaceutical preparations, and topical formulations.
Hydrogenated Castor Oil Powder has also been used as a polymerization aid for the production of insoluble polymers, including polyurethane elastomers.
Hydrogenated Castor Oil Powder is an extremely versatile oleochemical that has a number of industrial and manufacturing applications.


Because of its excellent resistance to moisture, Hydrogenated Castor Oil Powder works extremely well as a viscosity modifier, and it also provides significant improvement in grease and oil resistance.
Personal Care: There are multiple Hydrogenated Castor Oil Powder uses in the manufacturing of personal care products, particularly as an emollient and thickening agent in ointments and deodorants, as well as hair care products and certain cosmetics.


Waxes: Hydrogenated Castor Oil Powder works as a binding agent in synthetic and petroleum waxes, as it makes the wax harder and more resistant to crumbling.
Soaps and Detergents: Hydrogenated Castor Oil Powder is sometimes used as an emulsifying agent in liquid soaps and detergents to enhance the stability of the liquid formula.


Textiles: Hydrogenated Castor Oil Powder makes an effective processing agent in various textile manufacturing applications.
Lubricants and Greases: Hydrogenated Castor Oil Powder is used as a thickening agent in lithium grease and lithium complex grease, as well as multipurpose greases and metal-drawing lubricants.


Hydrogenated Castor Oil Powder has a very wide use in the industries like: Lubricants, Paper Coatings, Processing Aids, Polishes, Investment Castings, Inks, Pencil & Crayons, Cosmetics, Electrical Applications, Hot Melt Adhesives.
Hydrogenated Castor Oil Powder is also used in the cosmetics sector.


There are numerous applications of Hydrogenated Castor Oil Powder in various industrial segments, such as a slip additive in paints, plastics (PE), and inks and as a dispersing agent in carbon papers, inks, and plastic color master batches and as a dispersing additive and flow control in sealants, hot-melt adhesives, powder coatings, and more.


There are many applications such as lubricants, plastics, and multipurpose industrial greases.
Hydrogenated Castor Oil Powder has a very high oxidative stability and acts very effectively as an internal and external lubricant in polymers.
This is an oil wit flexibility and ductility for the manufacturer of industrial resins, plastics, elastomers, dielectric, rubber products in general.


Hydrogenated Castor Oil Powder is widely used in the production of multi-purpose calcium and lithium lubricating greases.
Lubricating greases produced from Hydrogenated Castor Oil Powder exhibit excellent resistances to oils and fats, water and solvents and they endue a long-life stability.


Hydrogenated Castor Oil Powder also is importand as thixotropic agent or as raw material in the production thereof for solvent-based coating systems.
Other technical application fields of Hydrogenated Castor Oil Powder are the use as processing aid for phenolic resins, polyethylene, PVC and rubber and as additive in the application of powder coatings. Non-drying alkyd resins can also be produced out of Hydrogenated Castor Oil Powder.


Hydrogenated Castor Oil Powder is of importance concerning the production of hot melts like paper coatings for food packaging and the production of hot melt adhesives.
In several types of polishes (for cars, shoes, furniture) Hydrogenated Castor Oil Powder is an ingredient.


Another important field is the use of Hydrogenated Castor Oil Powder and its derivatives (e. g. ethoxylated HCO) in cosmetics like creams, lipsticks etc.
Hydrogenated Castor Oil Powder is used Adhesives, Emulsifiers, and Lubricants.
Hydrogenated Castor Oil Powder is a wax used in applications ranging from the manufacture of lithium and calcium greases, hot melts in sealants and coatings, mold release agents for plastic or rubber, paper coats, and personal care.


Hydrogenated Castor Oil Powder is hard and brittle with a high melting point, and is suitable for us as a structurant for antiperspirant sticks or lipstick.
Hydrogenated Castor Oil Powder — also called HCO or castor wax — is a hard, white, opaque vegetable wax.
Its resistance to moisture makes Hydrogenated Castor Oil Powder useful in many coatings, greases, cosmetics, polishes and similar applications.


Hydrogenated Castor Oil Powder is created by hydrogenating pure liquid castor oil, which is obtained from castor beans.
Hydrogenated Castor Oil Powder is heated under extreme pressure using a nickel catalyst during the hydrogenation process.
Afterward, the hydrogen creates saturated molecules of castor wax, which gives Hydrogenated Castor Oil Powder a higher melting point that allows it to remain solid at room temperature.


After hydrogenation, Hydrogenated Castor Oil Powder becomes hard and brittle to the touch.
greases uses of Hydrogenated Castor Oil Powder: Lithium- and Calcium hydroxystearates dispersed in base oil to make multipurpose greases having higher dropping points, hardness, better rust-proofing, lubricity and durability than stearates.


Other lubricants: Hydrogenated Castor Oil Powder is used metal drawing lubes, PVC lubricants for PVC pipes, profiles, sheets, pharma tabletting, metal powders, ceramics.
Hydrogenated Castor Oil Powder is used as a thickener, emulsifier in cosmetics.


Hydrogenated Castor Oil Powder is used in ointments as well as fragrances.
Hydrogenated Castor Oil Powder is used manufacturing of candles, lipsticks and crayons.
Hydrogenated Castor Oil Powder is a hard brittle, high melting point waxy substance with faint characteristic of fatty wax odor and is tasteless.


Hydrogenated Castor Oil Powder is compatible with beeswax, carnauba and candelilla wax.
Hydrogenated Castor Oil Powder is relatively insoluble in most organic solvents though it will dissolve in a number of solvents and oils at an elevated temperature but on cooling will form gels or a paste like mass.


Hydrogenated Castor Oil Powder forms a smooth, stable anionic emulsion with emulsifiers and triethanolamine stearate. Hydrogenated Castor Oil Powder can also be emulsified with a cationic emulsifying agent, making emulsions that are also stable.
Hydrogenated Castor Oil Powder is mainly used in plastics, textiles, lubricants etc.


Hydrogenated Castor Oil Powder is used Castor Oils & Castor Oil Derivatives, Flavor & Fragrance, Inks & Digital Inks, Lubricant & Grease, Plastic, Resin & Rubber, Nutritionals
Hydrogenated Castor Oil Powder finds a number of diversified uses due to its unique combination of physicochemical properties.


Hydrogenated Castor Oil Powder is used in the manufacture of multipurpose Lithium/Calcium grease and high-performance aviation grease.
Hydrogenated Castor Oil Powder is used in the manufacture of soaps & cosmetics.
Hydrogenated Castor Oil Powder is used as mould release agent in the processing of plastics and rubbers.


Hydrogenated Castor Oil Powder is used as a component of specialty wax blends like pencils, crayons, lipsticks and anti-deodorant sticks.
Hydrogenated Castor Oil Powder is used in the manufacture of hot-melt coatings and sealant requiring resistance to water.
Hydrogenated Castor Oil Powder is used as a coating agent for paper & as anti-foaming agent.


Hydrogenated Castor Oil Powder is used in the manufacture of Automotive refinish Acrylics.
Hydrogenated Castor Oil Powder is used rheological agent that provides thixotropic in paints, coatings, inks, adhesives, sealants and numerous industrial compositions.


Hydrogenated Castor Oil Powder is used thick film chlorinated rubber, epoxy and vinyl coating.
Hydrogenated Castor Oil Powder is used flame Retardant and anti-static agent for fiber.
Hydrogenated Castor Oil Powder is used manufacture of Spin finish oil for polyamide fiber.


Hydrogenated Castor Oil Powder is used in preparation of ointments, emulsified virus vaccines, sustained release capsules, wetting/bodying agent, face paint.
Hydrogenated Castor Oil Powder is used as plasticizer for cellulosic.
Hydrogenated Castor Oil Powder is used processing aid for Colour concentrates.


Hydrogenated Castor Oil Powder is used surface treatment agents.
Hydrogenated Castor Oil Powder is used in the manufacture of hot melt adhesives used in packaging books, binding footwear, carpet backing and in product assembly.


Hydrogenated Castor Oil Powder is used anti-tack and slip additives for processing plastics.
Hydrogenated Castor Oil Powder is used in the manufacture of specialty chemicals for applications such as metal working, plasticizers and textile auxiliaries in the form of derivatives such as esters, ethylates, sulfates etc.


Hydrogenated Castor Oil Powder is soluble in both water and oil and is traditionally used to emulsify and solubilize oil-in-water formulations.
Its foam-enhancing properties make Hydrogenated Castor Oil Powder ideal for use in liquid cleansers.
As a surfactant, Hydrogenated Castor Oil Powder helps to decrease the surface tension between multiple liquids or between liquids and solids.


Furthermore, Hydrogenated Castor Oil Powder helps to remove the grease from oils and causes them to become suspended in the liquid.
Hydrogenated Castor Oil Powder is used in the following products: polymers, lubricants and greases, paper chemicals and dyes, cosmetics and personal care products and pharmaceuticals.


Release to the environment of Hydrogenated Castor Oil Powder can occur from industrial use: formulation of mixtures, formulation in materials, manufacturing of the substance and in the production of articles.
Hydrogenated Castor Oil Powder is used in the following areas: formulation of mixtures and/or re-packaging.


Hydrogenated Castor Oil Powder is used in the following products: washing & cleaning products, polymers, metal surface treatment products, textile treatment products and dyes, lubricants and greases and pH regulators and water treatment products.


Hydrogenated Castor Oil Powder is used for the manufacture of: chemicals, , textile, leather or fur and plastic products.
Release to the environment of Hydrogenated Castor Oil Powder can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, as processing aid and for thermoplastic manufacture.


Release to the environment of Hydrogenated Castor Oil Powder can occur from industrial use: manufacturing of the substance, formulation of mixtures, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.
Hydrogenated Castor Oil Powder is used for Coatings and Greases.


Hydrogenated Castor Oil Powder is utilized in the Manufacture of Waxes, Polishes, Carbon Paper, Candles and Crayons.
Hydrogenated Castor Oil Powder finds Use in Cosmetics, Hair Dressing, Ointments, and in Preparation of Hydroxyl-stearic Acid.
Hydrogenated Castor Oil Powder is used as a Paint Additive, Pressure Mould Release Agent in the Manufacture of Formed Plastics and Rubber Goods.


It is this insolubility that makes Hydrogenated Castor Oil Powder valuable to the lubricants markets. It is perfect for metal drawing lubricants and multipurpose industrial greases.
Hydrogenated Castor Oil Powder is used in polishes, cosmetics, electrical capacitors, carbon paper, lubrication, and coatings and greases where resistance to moisture, oils and petrochemical products is required.


Hydrogenated Castor Oil Powder is used as the Reaction Itself is Exothermic, the Chief Energy Requirements are in the Production of Hydrogen, Warming of the Oil, Pumping, and Filtering.
Hydrogenated Castor Oil Powder is known for its versatility and is used in various industries and applications due to its unique characteristics.


Inks & Toner: Hydrogenated Castor Oil Powder can be used in the formulation of environmentally friendly inks and toners, contributing to sustainable printing and imaging solutions.
Lubricants & Greases: In lubricants and greases, Hydrogenated Castor Oil Powder may act as a natural and renewable ingredient, providing eco-conscious solutions for machinery and mechanical systems.


Adhesives & Sealants: Hydrogenated Castor Oil Powder is employed in adhesives and sealants, offering natural and renewable components for eco-friendly bonding solutions.
Coatings & Paints: Hydrogenated Castor Oil Powder can be incorporated into coatings and paints to enhance their performance, sustainability, and eco-friendliness.


Packaging: Hydrogenated Castor Oil Powder can be used in eco-conscious packaging materials and coatings, promoting sustainability in packaging solutions.
Cosmetics & Care: In cosmetics, personal care products, and skincare formulations, Hydrogenated Castor Oil Powder contributes to natural and eco-friendly products.


Pharmaceuticals: Hydrogenated Castor Oil Powder may find applications in pharmaceutical formulations and drug delivery systems.
Tire & Rubber: In the tire and rubber industry, Hydrogenated Castor Oil Powder can be employed in rubber compound formulations to enhance processing and performance.


Wax Blenders: Hydrogenated Castor Oil Powder is used in the formulation of wax blends for various applications, providing eco-friendly alternatives in wax-based products.
Cleaning & Household: Hydrogenated Castor Oil Powder can find applications in eco-friendly cleaning products and household items, contributing to sustainable and natural alternatives.


Agriculture: Hydrogenated Castor Oil Powder may have agricultural applications, such as in crop protection formulations and soil conditioning products, promoting sustainable agricultural practices.
Hydrogenated Castor Oil Powder is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Hydrogenated Castor Oil Powder is used in the following products: washing & cleaning products, lubricants and greases, adhesives and sealants, polishes and waxes, fertilisers, coating products and air care products.


Other release to the environment of Hydrogenated Castor Oil Powder is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Hydrogenated Castor Oil Powder can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release, industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).


Other release to the environment of Hydrogenated Castor Oil Powder is likely to occur from: indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Hydrogenated Castor Oil Powder can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and vehicles.


Hydrogenated Castor Oil Powder can be found in products with material based on: metal (e.g. cutlery, pots, toys, jewellery), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), plastic (e.g. food packaging and storage, toys, mobile phones), leather (e.g. gloves, shoes, purses, furniture) and rubber (e.g. tyres, shoes, toys).


Hydrogenated Castor Oil Powder is used in the following products: washing & cleaning products and polishes and waxes.
Hydrogenated Castor Oil Powder is used in the following areas: formulation of mixtures and/or re-packaging.
Hydrogenated Castor Oil Powder is used for the manufacture of: chemicals and .


Other release to the environment of Hydrogenated Castor Oil Powder is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).


-Applications of Hydrogenated Castor Oil Powder in Various Industries:
Hydrogenated Castor Oil Powder finds a wide range of applications across different sectors.
Its versatility and excellent properties make Hydrogenated Castor Oil Powder an essential ingredient in various industries.


-Pharmaceutical and Cosmetic Applications of Hydrogenated Castor Oil Powder:
The pharmaceutical and cosmetic industries extensively use hydrogenated castor oil powder.
Hydrogenated Castor Oil Powder is used as a key ingredient in the production of ointments, emulsified virus vaccines, sustained-release capsules, and face paint.

Its ability to act as a wetting and bodying agent makes Hydrogenated Castor Oil Powder useful in the preparation of different pharmaceutical formulations.
In the cosmetic industry, Hydrogenated Castor Oil Powder is used in the manufacture of soaps, shampoos, creams, and lotions due to its stable nature and high-drop point


-Industrial Applications of Hydrogenated Castor Oil Powder in the Production of Greases, Lubricants, and Adhesives:
Hydrogenated Castor Oil Powder is widely used in the production of greases, lubricants, and adhesives.
Its viscosity-modifying properties make Hydrogenated Castor Oil Powder an excellent choice for improving the grease and oil resistance of these products.
The powder form is particularly suitable for hot-melt adhesives, where Hydrogenated Castor Oil Powder enhances the adhesion and strength of the adhesive.
Additionally, Hydrogenated Castor Oil Powder is used as a mold release agent in the processing of plastics and rubbers.


-Use of Hydrogenated Castor Oil Powder in Rubber, Plastic, Polishes, and Coatings:
Hydrogenated Castor Oil Powder plays a crucial role in the rubber, plastic, polishes, and coatings industries.
It is known for its excellent dispersal level in powder coatings and its ability to enhance the performance of elastomers and sealants.
In rubber and plastic applications, it improves the resistance to moisture, oil, and other petrochemical products.
Furthermore, it finds use in polishes and coatings where it provides durability and a glossy finish


-Topical formulations:
In topical formulations, Hydrogenated Castor Oil Powder can be used as consistency factor to enhance the viscosity of the formulation.
The typical concentration at about 0.1-2% Hydrogenated Castor Oil Powder is compatible with most natural vegetable and animal waxes and can therefore be used in combination with fatty alcohols and other consistency factors.

Similar to emollients, waxes affect the sensory profile and the stability of a topical formulation.
They are solid at ambient temperatures and stabilize emulsions as the viscosity is increased by formation of lamellar structures in oil-in-water formulations.

Furthermore Hydrogenated Castor Oil Powder has a special advantage because of its high melting point and is able to support the formulation stability particularly at elevated temperatures.


-Lubricant in tablet and capsule formulations:
Lubricants prevent ingredients from clumping together and from sticking to the tablet punches or capsule filling machine.
Lubricants also ensure that tablet formulations and ejection can occur with low friction.

Common minerals like talc or silica, and fats, e.g. vegetable stearin, magnesium stearate or stearic acid, are most frequently used lubricants in tablets or hard gelatin capsules.
Lubricants are added in small quantities to tablet or capsule formulations to improve certain processing characteristics.

In tablet formulations Kolliwax® HCO can be used as a lubricant as an effective alternative to magnesium stearate.
Hydrogenated Castor Oil Powder is compatible to a large number of actives and does not provide a metallic taste.
Hydrogenated Castor Oil Powder is particularly suitable for formulation of sensitive APIs.


-Plasticizer in solid dispersions:
In solid dispersions, Hydrogenated Castor Oil Powder is used as plasticizer in solid polymeric matrices.
Hydrogenated Castor Oil Powder is suitable for melt granulation, spray drying and hot melt extrusion processes.


-Plastics uses of Hydrogenated Castor Oil Powder:
Hydrogenated Castor Oil Powder performs the role of a lubricant and release agent for PVC and improves processing, dispersion and grease resistance of sheeted polyethylene.
Hydrogenated Castor Oil Powder is also useful in the preparation of various polyurethane coating formulas.


-cosmetics uses of Hydrogenated Castor Oil Powder: Hydrogenated Castor Oil Powder of different melting points used in lipsticks, deodorant and antiperspirant sticks, cosmetic creams.
slip additive in inks, paints, plastics (PE).

Hydrogenated Castor Oil Powder is used dispersing agent in plastic colour master batches, carbon papers, inks.
Hydrogenated Castor Oil Powder is used flow control and dispersing additive in powder coatings, hot-melt adhesives and sealants.
Hydrogenated Castor Oil Powder is used shoe polishing, furniture polishing creams.


-Pharmaceutical Applications
Hydrogenated Castor Oil Powder is a hard wax with a high melting point used in oral and topical pharmaceutical formulations.
In topical formulations, Hydrogenated Castor Oil Powder is used to provide stiffness to creams and emulsions.

In oral formulations, Hydrogenated Castor Oil Powder is used to prepare sustained-release tablet and capsule preparations; the Hydrogenated Castor Oil Powder may be used as a coat or to form a solid matrix.
Hydrogenated Castor Oil Powder is additionally used to lubricate the die walls of tablet presses; and is similarly used as a lubricant in food processing.
Hydrogenated Castor Oil Powder is also used in cosmetics.



WHAT IS HYDROGENATED CASTOR OIL POWDER USED FOR?
Hydrogenated Castor Oil Powder is a natural powerhouse ingredient overflowing with benefits for both hair and skin.

*Skin care:
Hydrogenated Castor Oil Powder acts as an outstanding emollient that deeply nourishes the surface and prevents moisture loss.
Hydrogenated Castor Oil Powder soothes the skin against sunburn and treats signs of aging like wrinkles.
Hydrogenated Castor Oil also has antibacterial properties making it potent for fighting acne


*Cosmetic products:
Apart from its emollient properties, Hydrogenated Castor Oil Powder is quite beneficial as a binding agent that keeps formulations together and stabilizes them.
Hydrogenated Castor Oil Powder is a great thickening agent and gives products a rich, luxurious consistency.
In cosmetics, Hydrogenated Castor Oil Powder works wonders for dry skin and lips


*Hair care:
Hydrogenated Castor Oil Powder has remarkable perks for overall hair health.
Hydrogenated Castor Oil Powder aids the rapid growth of hair, eyelashes, and eyebrows while keeping them healthy and nourished.
Long-term use of Hydrogenated Castor Oil Powder on hair leaves them lustrous, thick, and frizz-free



KEY FEATURES OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is solid castor powder of high-melting-point.
This is safely derived after the process of hydrogenation of refined castor oil.
Hydrogenated Castor Oil Powder is a non-hazardous as well as non-toxic product.



BENEFITS OF HYDROGENATED CASTOR OIL POWDER:
*At room temperature Hydrogenated Castor Oil Powder is a hard wax with a high melting point (85-88°C)
*Hydrogenated Castor Oil Powder has unique particle size distribution
*Hydrogenated Castor Oil Powder is particularly suitable for the formulation of sensitive APIs
*Hydrogenated Castor Oil Powder is compatible with several natural vegetable and animal waxes, as well as fatty alcohols to enhance viscosity of topical formulations
*Hydrogenated Castor Oil Powder is suitable as a plasticizer for melt granulation, spray drying, Hot melt extrusion



FUNCTIONALITIES OF HYDROGENATED CASTOR OIL POWDER:
*Additives,
*Lubricants,
*Film formers,
*Viscosity modifiers



ORIGIN OF HYDROGENATED CASTOR OIL POWDER:
Castor oil is derived from castor beans, also known as ricinus communis, which is native to India, China, and Brazil.
This oil undergoes a hydrogenation process which involves reacting castor oil with hydrogen gas in the presence of a catalyst, typically nickel or palladium.

During hydrogenation, unsaturated fatty acids present in castor oil undergo saturation, converting double bonds into single bonds.
This results in a more solid and stable form of castor oil with improved oxidative stability and increased melting point.
The resulting Hydrogenated Castor Oil is then purified to remove impurities and make it safe for use in cosmetics.



WHAT DOES HYDROGENATED CASTOR OIL POWDER DO IN A FORMULATION?
*Binding
*Emollient
*Skin conditioning
*Soothing
*Viscosity controlling



SAFETY PROFILE OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil is non-toxic and extremely safe for use on hair and skin.
However, cosmetic-grade Hydrogenated Castor Oil is cleaned of all impurities and does not pose any risks.
Hydrogenated Castor Oil Powder is also non-comedogenic, providing a safe solution for hydration without clogging the pores.
Further, Hydrogenated Castor Oil Powder is vegan, halal, and kosher-certified.



ALTERNATIVES OF HYDROGENATED CASTOR OIL POWDER:
*HYDROGENATED VEGETABLE OIL



CHEMICAL PROPERTIES OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated castor oil occurs as a fine, almost white or pale yellow powder or flakes. The PhEur 6.0 describes hydrogenated castor oil as the oil obtained by hydrogenation of virgin castor oil. It consists mainly of the triglyceride of 12-hydroxystearic acid.



FUNCTIONS OF HYDROGENATED CASTOR OIL POWDER:
*Emulsifier,
*Plasticizer



WHAT ARE THE KEY BENEFITS OF USING HYDROGENATED CASTOR OIL POWDER IN COSMETICS?
Hydrogenated Castor Oil Powder offers several benefits when used in cosmetics.
Hydrogenated Castor Oil Powder acts as an excellent emollient, providing hydration and moisturization to the skin.

Hydrogenated Castor Oil Powder also helps in the formulation of various cosmetic products such as creams, lotions, and shampoos by enhancing their stability and texture.
The high-drop point of Hydrogenated Castor Oil Powder ensures that the products remain stable even at elevated temperatures.

In conclusion, Hydrogenated Castor Oil Powder is a versatile ingredient with various applications in pharmaceuticals, cosmetics, and industrial sectors.
Its unique properties and exceptional stability make Hydrogenated Castor Oil Powder an ideal choice for improving the performance of greases, lubricants, adhesives, rubber, plastic, polishes, and coatings.



FEATURES OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is a hard, wax-like substance extracted from castor oil beans.
There is also a petroleum-based formula of Hydrogenated Castor Oil Powder known as PEG-40.
The Hydrogenated Castor Oil Powder chemical formula of this material is C57H110O9(CH2CH2O)n.



SAFETY OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is used in oral and topical pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material.



STORAGE OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is stable at temperatures up to 1508℃. Clear, stable, chloroform solutions containing up to 15% w/v of Hydrogenated Castor Oil Powder may be produced.
Hydrogenated Castor Oil Powder may also be dissolved at temperatures greater than 908℃ in polar solvents and mixtures of aromatic and polar solvents, although the Hydrogenated Castor Oil Powder precipitates out on cooling below 908℃.
Hydrogenated Castor Oil Powder should be stored in a well-closed container in a cool, dry place.



INCOMPATIBILITIES OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is compatible with most natural vegetable and animal waxes.



PRODUCTION METHODS OF HYDROGENATED CASTOR OIL POWDER:
Hydrogenated Castor Oil Powder is prepared by the hydrogenation of castor oil using a catalyst.



UNIQUE PROPERTIES OF HYDROGENATED CASTOR OIL POWDER:
*Emollient:
Hydrogenated Castor Oil Powder has emollient properties, making it suitable for skin-care and cosmetic products, providing moisturization and a smooth texture.

*Thickening:
Hydrogenated Castor Oil Powder can serve as a thickening agent in various formulations, enhancing their viscosity and stability.

*Lubrication:
Hydrogenated Castor Oil Powder functions as a lubricant, reducing friction and providing a smooth surface in pharmaceutical and industrial applications.

*Release Agent:
In food processing, Hydrogenated Castor Oil Powder acts as a release agent, preventing sticking and enhancing the release of products from molds and equipment.

*Plasticizer:
In plastics and coatings, Hydrogenated Castor Oil Powder can function as a plasticizer, improving flexibility and durability.

*Alternative for:
The choice of using hydrogenated castor oil depends on specific application requirements.
Alternatives may include other types of oils, waxes, or chemical compounds that provide similar properties, depending on the desired characteristics and environmental considerations.

The selection is influenced by factors such as emollient properties, thickening ability, lubrication, release properties, and cost considerations.
Hydrogenated Castor Oil Powder is preferred when its unique combination of properties aligns with the application's needs, particularly in cosmetics, pharmaceuticals, and food processing, where its safety and performance benefits are valued.



PHYSICAL and CHEMICAL PROPERTIES of HYDROGENATED CASTOR OIL POWDER:
Appearance: White flakes
Iodine Value, gI2/100g: 3 MAX
Saponification Value, mg KOH/g: 175 - 185
Acid Value, mg KOH/g: 3 MAX
Hydroxyl Value, mg KOH/g: 155 MIN
Melting Point, °C: 84 - 88
Gardner Color: 3 MAX
CAS: 8001-78-3
EINECS: 232-292-2
Density: 0.97 g/cm3 at 20°C

Solubility: Practically insoluble in water; soluble in acetone,
chloroform, and methylene chloride.
Vapor Pressure: 0 Pa at 20°C
Appearance: Powder
Storage Condition: Room Temperature
Stability: Stable.
Additional Information:
Appearance: White to pale yellow powder, lump, or flake.
Base Number: Not more than 4.0.
Melting Point: 85-88 °C.
Hydroxyl Value: 150-165.
Iodine Value: Not more than 5.0.
Saponification Value: 176-182.
Color: 3

Appearance: White to creamish flakes or powder
Density (20°C): 0.970
Refractive index: N.A.
Melting point (°C): 83 - 87
Acid Value (mg KOH/g): 0.0 - 3.0
Gardner color: 0.0 - 3.0
Hydroxyl value (mg KOH/g): 180.0000
Melting point (°C): 85 - 88
Nickel content (ppm): 3
Saponification value (mg KOH/g): 0
Specific Gravity (25°C): 1.02
Color: White to Pale Yellowish
Appearance @ 20°C: Solid (Mobile liquid @ 30°C)
Odor: Almost none

Density: 0.97g/cm3 at 20℃
Vapor pressure: 0Pa at 20℃
Solubility: Practically insoluble in water; soluble in acetone,
chloroform, and methylene chloride.
Form: Powder
Dielectric constant: 10.3 (27℃)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
LogP: 18.75
FDA 21 CFR: 178.3280; 175.300; 176.170; 177.1200; 177.1210
Indirect Additives used in Food Contact Substances: CASTOR OIL, HYDROGENATED
EWG's Food Scores: 1
FDA UNII: ZF94AP8MEY
EPA Substance Registry System: Hydrogenated castor oil (8001-78-3)
Appearance: White flakes or powder

Odor: Like hardened vegetable oil
pH: Neutral
Boiling Point: > 300°C
Melting Point: 82 - 87°C
Flash Point: Above 310°C
Flammability (solid, gas): None
Auto flammability: None
Explosive Properties: Dust explodable
Oxidizing Properties: None
Vapor Pressure: Not applicable
Relative Density: About 0.99 at 25°C
Solubility - Water solubility: Insoluble
Fat solubility: Insoluble in most organic solvents at room temperature
Partition coefficient: n-octanol/water: Not available
Melting Point: 85°C
Solubility: Insoluble in water
Viscosity: High



FIRST AID MEASURES of HYDROGENATED CASTOR OIL POWDER:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROGENATED CASTOR OIL POWDER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HYDROGENATED CASTOR OIL POWDER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROGENATED CASTOR OIL POWDER:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROGENATED CASTOR OIL POWDER:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of HYDROGENATED CASTOR OIL POWDER:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


HYDROGENATED COCONUT OIL
HYDROGENATED PALM ACID N° CAS : 84238-17-5 Nom INCI : HYDROGENATED PALM ACID N° EINECS/ELINCS : 282-486-6 Classification : Huile hydrogénée Ses fonctions (INCI) Opacifiant : Réduit la transparence ou la translucidité des cosmétiques
HYDROGENATED PALM ACID
Hydrogenated Palm Stearin; Palm stearin; palm oil; Palm Oil and Palm Kernel Oil; Glycerides, mixed hydrogenated palm kernel-oil stearin and hydrogenated palm-oil cas no: 100298-99-5
HYDROGENATED PALM GLYCERIDES
Hydrogenated palm glycerides are the fatty acid component of palm oil.
Hydrogenated palm glycerides can be used for stable emulsions in the range up to pH 7.


CAS Number: 91744-66-0
EC Number: 294-631-0
Classification: Hydrogenated oil, Palm oil (Derivative)
Bio-compatible (COSMOS Reference)
Origin: Botanical, Synthetic
Molecular Formula: CH3(CH2)7CHCH(CH2)7COOCH3



SYNONYMS:
Hydrogenated Palm Oil Glycerides, Hydrogenated palm glyceride, Glycerides, palm oil mono-, hydrogenated, Palm oil glyceride, hydrogenated, HYDROGENATED GLYCERYL PALMATE, HYDROGENATED PALM GLYCERIDES, HYDROGENATED PALM GLYCERIDES [INCI], MONOMULS 60-35C, PALM-OIL GLYCERIDES, MONOGLYCERIDES, DIGLYCERIDES AND TRIGLYCERIDES, HYDROGENATED, diglycerides and triglycerides, hydrogenated Glycerides palm-oil mono-, di- and tri-, hydrogenated, hydrogenated palm glycerides, glycerides, palm oil, hydrogenated, glycerides, palm-oil mono-, di- and tri-, hydrogenated, glycerides,palm-oil mono-, di- and tri-, hydrogenated, diglycerides, palm-oil,monoglycerides, diglycerides and triglycerides, hydrogenated, monoglycerides,palm-oil, monoglycerides, diglycerides and triglycerides, hydrogenated, monomuls 60-35c, glycerides, palm-oilmonoglycerides, DI- AND TRI- HYDROGENATED GLYCERIDES, PALM OIL MONO-, GLYCERIDES, PALM OIL MONO-, DI- AND TRI-, HYDROGENATED, GLYCERIDES, PALM-OIL MONO-, DI- AND TRI-, HYDROGENATED, HYDROGENATED GLYCERIDES, PALM OIL MONO-, DI- AND TRI-, and HYDROGENATED PALM GLYCERIDES



Hydrogenated palm glycerides are an end product of controlled hydrogenation of Palm oil glycerides (q.v.).
Hydrogenated palm glycerides are a natural thickener for oil phase. Low melting point saturated glycerides particularly appropriate for sticks and crayons.
This vegetable emulsifier, Hydrogenated palm glycerides, is very well suited for the production of O/W emulsions.


Hydrogenated palm glycerides can be used for stable emulsions in the range up to pH 7.
If you incorporate raw materials from the acidic range (such as aloe vera), Hydrogenated palm glycerides is better to use an additional co-emulsifier (such as emulsan).


Then formulations of Hydrogenated palm glycerides in the pH range of 5-6 are also possible.
Hydrogenated palm glycerides are the fatty acid component of palm oil.
Hydrogenation allows the oily liquid to remain in a solid state at room temperature.


Hydrogenated palm glycerides are palm glycerols that transform into the structure of a specific molecule by reacting with the hydrogen atom.
The hydrogenation process is kept under control and only a certain number of hydrogen atoms can react.
Hydrogenation helps any oil change from liquid to solid at room temperature.


Hydrogenated palm glycerides are the fatty acid component of palm oil.
Hydrogenation allows the oily liquid to remain in a solid state at room temperature.



USES and APPLICATIONS of HYDROGENATED PALM GLYCERIDES:
This fatty acid derivative, Hydrogenated palm glycerides, is used to stabilize or thicken the product.
Cosmetic Uses of Hydrogenated palm glycerides: skin conditioning, surfactants, and surfactant - emulsifying.
Hydrogenated palm glycerides are obtained from the fat content of palm oil.


Hydrogenated palm glycerides contain large amounts of oil.
As a result, Hydrogenated palm glycerides can nourish dry skin.
Hydrogenated palm glycerides can moisturize the skin by creating an occlusive or waterproof film on the skin or hair.


This film can protect the skin from environmental damage and also keep moisture close to the skin.
It keeps the skin soft and nourished.
Hydrogenated palm glycerides have both a moisture-loving and oil-loving structure.


Therefore, Hydrogenated palm glycerides are best used as emulsifiers.
The hydrogenated variety is more stable and can be used to increase viscosity as Hydrogenated palm glycerides transform from almost semi-solid to solid at room temperature.


Hydrogenated palm glycerides are used in skin care, sun care, make-up and SPF increasing.
Hydrogenated palm glycerides are an End prod. of controlled hydrogenation of palm glyceride.


Hydrogenated palm glycerides use and applications include: Emollient; emulsifier, stabilizer, dispersant, opacifier for cosmetics, foods, and pharmaceuticals; dispersant, mold release agent, processing aid, antistat, antifog, lubricant, antiblocking agent for PS, polyolefins, PVC, PU; defoamer in food-contact paperpaperboard; in food-contact textiles; thickener



INDUSTRY OF HYDROGENATED PALM GLYCERIDES:
Industry
*Cosmetic ,
*Pharmaceutical ,
*Textiles



FUNCTIONS OF HYDROGENATED PALM GLYCERIDES:
*Emulsifier ,
*Dispersant ,
*Stabilizer ,
*Lubricant



FUNCTIONS OF HYDROGENATED PALM GLYCERIDES:
*Emollient :
Hydrogenated palm glycerides softens and smoothes the skin
*Emulsifying :
Hydrogenated palm glycerides pthe formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil)
*Skin conditioning :
Hydrogenated palm glycerides maintains skin in good condition
*Viscosity controlling :
Hydrogenated palm glycerides increases or decreases the viscosity of cosmetics



FUNCTIONS OF HYDROGENATED PALM GLYCERIDES IN COSMEIC PRODUCTS:
*SKIN CONDITIONING
Hydrogenated palm glycerides maintains the skin in good condition

*SKIN CONDITIONING - EMOLLIENT
Hydrogenated palm glycerides softens and smoothens the skin

*SURFACTANT - EMULSIFYING
Hydrogenated palm glycerides allows the formation of finely dispersed mixtures of oil and water (emulsions)

*VISCOSITY CONTROLLING
Hydrogenated palm glycerides increases or decreases the viscosity of cosmetic products



ORIGIN OF HYDROGENATED PALM GLYCERIDES:
Hydrogenated palm glycerides is a plant/synthetic



ALL FUNCTIONS OF HYDROGENATED PALM GLYCERIDES:
Moisturizing (Occlusive), Emollient,Emollients fill the micro-cracks in the skin and leave it feeling soft and pleasant to the touch.
Emollients are often mistakenly perceived as moisturizing ingredients. Emulsifying, Viscosity Controlling



WHAT IS HYDROGENATED PALM GLYCERIDES?
Hydrogenated palm glycerides are the fatty acid component of palm oil.



WHAT ARE OTHER NAMES FOR HYDROGENATED PALM GLYCERIDES?
DI- AND TRI- HYDROGENATED GLYCERIDES, PALM OIL MONO-, GLYCERIDES, PALM OIL MONO-, DI- AND TRI-, HYDROGENATED, GLYCERIDES, PALM-OIL MONO-, DI- AND TRI-, HYDROGENATED, HYDROGENATED GLYCERIDES, PALM OIL MONO-, DI- AND TRI-, and HYDROGENATED PALM GLYCERIDES



WHAT IS HYDROGENATED PALM GLYCERIDES USED FOR
How Hydrogenated palm glycerides are classified;
Antioxidants, Skin-Replenishing, Emollients



RECOMMENDATIONS FOR USING HYDROGENATED PALM GLYCERIDES DURING PREGNANCY AND BREASTFEEDING:
Limited data suggests no known risk



FUNCTIONS OF HYDROGENATED PALM GLYCERIDES:
*Emollient :
Hydrogenated palm glycerides softens and smoothes the skin
*Skin conditioning :
Hydrogenated palm glycerides maintains skin in good condition



PHYSICAL and CHEMICAL PROPERTIES of HYDROGENATED PALM GLYCERIDES:
CAS Number: 91744-66-0
Molecular Weight: N/A
Density: N/A
Boiling Point: N/A
Molecular Formula: N/A
Melting Point: N/A
MSDS: N/A
Flash Point: N/A



FIRST AID MEASURES of HYDROGENATED PALM GLYCERIDES:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROGENATED PALM GLYCERIDES:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HYDROGENATED PALM GLYCERIDES:
FIRE FIGHTING MEASURES of AMPS SODIUM SALT:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROGENATED PALM GLYCERIDES:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROGENATED PALM GLYCERIDES:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of HYDROGENATED PALM GLYCERIDES:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


HYDROGENATED PALM STEARIN
Hydrogenated Palm Stearin is more variable in composition than palm olein, the liquid fraction of palm oil, especially in terms of its solid fat content, and therefore has more variable physical characteristics.
Hydrogenated Palm Stearin is the solid fraction of palm oil that is produced by partial crystallization at controlled temperature.


CAS number: 91079-14-0
EC number: 293-400-1



Hydrogenated Palm Stearin is insoluble in water, slightly soluble in gasoline, and soluble in acetone, benzol, chloroform, and alcohol.
Hydrogenated Palm Stearin is a source for producing specialty fats for coating in confectionery and the manufacturing of oleochemicals.
Hydrogenated Palm Stearin provides functional and structural stability to foods and improves shelf life.


In normal temperature, Hydrogenated Palm Stearin is white or slight yellow solid wax, non-soluble in water, little soluble in gasoline, soluble in acetone, benzol, chloroform, alcohol, etc, stable chemical properties.
Hydrogenated Palm Stearin is a excellent fat with good stability for the bakery industry.


Hydrogenated Palm Stearin's provides the essential solid fat content and stable beta prime crystalline when used in margarine an shortening production.
For industrial application such as candle industry, Hydrogenated Palm Stearin can be an alternative raw material for cost saving and also more environtmentally friendly.


Palm stearin is the co-product of the palm oil refining process.
The product undergoes a hydrogenation process to become hydrogenated palm stearin.
The difference between hydrogenated and regular RBD palm stearin is the number of unsaturated chains of fatty acid molecules.


Hydrogenated Palm Stearin is known for its higher melting point than regular RBD palm stearin.
At normal temperature, Hydrogenated Palm Stearin appears white to a slightly yellow solid wax.
Hydrogenated Palm Stearin is obtained from oil palm (Elaeis guineensis), after a process of refining, bleaching and deodorizing, resulting in a palm oil known as RBD (Refined, Bleached and Deodorised).


After this process Hydrogenated Palm Stearin is subjected to a fractionation at low temperature, its crystallization and subsequent filtration.
The solid, palmitic acid rich fraction is known as Hydrogenated Palm Stearin, while the liquid part is palm olein (rich in oleic acid).
Hydrogenated Palm Stearin is a white to pale yellowish solid at room temperature.


Hydrogenated Palm Stearin's melting range is between 47 and 54ºC.
Hydrogenated Palm Stearin is the solid fraction of palm oil that is produced by partial crystallization at controlled temperature.
Hydrogenated Palm Stearin is a stearin in the sense of stearins and oleins being the solid and liquid fractions respectively of fats and oils; not in the sense of glyceryl tristearate.


Hydrogenated Palm Stearin is more variable in composition than palm olein, the liquid fraction of palm oil, especially in terms of its solid fat content, and therefore has more variable physical characteristics.
Like crude palm fruit oil, Hydrogenated Palm Stearin contains carotenoids, but physically refined palm oils do not, as they are removed or destroyed in the refining process.


Hydrogenated Palm Stearin is a useful source of natural hard vegetable fat for food applications.
Hydrogenated Palm Stearin consists of mostly glyceryl tripalmitate, with most of the rest of the fat content being glyceryl dipalmitate monooleate.
In terms of fatty acid composition, a typical soft Hydrogenated Palm Stearin might contain almost 50% palmitic acid and 35% oleic acid


As all vegetable oils and fats, Hydrogenated Palm Stearin is a triglyceride (a glycerol backbone linked to three fatty acids by ester bonds).
Hydrogenated Palm Stearin is characterized by a high proportion of palmitic acid (50-68%) and oleic acid (20-35%).
Other fatty acids presented in significant amounts are: linoleic acid (5-9%), stearic acid (4-6%) and myristic acid (1-2%).



USES and APPLICATIONS of HYDROGENATED PALM STEARIN:
Hydrogenated Palm Stearin is used as an essential raw material used by the shortening and margarine industries.
Hydrogenated Palm Stearin also can be used in making stearates, soap, polish cream, candles, cosmetics, and fertilizers.
Hydrogenated Palm Stearin is used in peanut butter, bakery mixes, breading mixes, seasoning mixes, and shortening.


Hydrogenated Palm Stearin is commonly used in the production of candles, soap, cosmetics, food, manufacturing industrial oils and other chemical products.
Its wide range of uses, diversity, and stability make Hydrogenated Palm Stearin an important raw material in many industrial and consumer goods fields.
Hydrogenated Palm Stearin can be used in making stearates, it can also be used in making MonoGlycerindes, soap, polish cream, and candles.


Food: Hydrogenated Palm Stearin is utilized as hardstock for margarine and shortening manufacturing
Industrial: Hydrogenated Palm Stearin can be mixed with paraffine wax for candle making.
Hydrogenated Palm Stearin is used in the production of different types of shortening and various margarine.


Hydrogenated Palm Stearin is the solid fraction from the fractionation of palm oil and blends with other vegetable oils to obtain suitable functional products such as margarine fats, shortenings, and vanaspati.
Hydrogenated Palm Stearin is used coating Substitution Material.


The solid fraction rich in palmitic acid is known as Hydrogenated Palm Stearin, while the liquid part is precisely the part known as olein.
As for its use, Hydrogenated Palm Stearin is very varied, since it can be used in animal feed or as a component in cosmetic products.
Among its many applications, and like the vast majority of fats, Hydrogenated Palm Stearin is used in human food.


They are an important source of energy, due to their high yield in calories per gram metabolised.
Their most important use is in cooking, especially as oil for frying or grilling.


Other very important applications of Hydrogenated Palm Stearin are in the field of oleochemistry and in almost all known industries, from cosmetics to animal feed, although their derivatives are also widely used as alternative fuels (biodiesel), soaps, lubricants, surfactants, advanced detergents, paints, dyes, insecticides, soaps and veterinary products.


Hydrogenated Palm Stearin use according to consistency: Soft consistency
Hydrogenated Palm Stearin has the ability to “aerate”, so it can be used for whipped candles.
Hydrogenated Palm Stearin is used creation of candles in containers.


Hydrogenated Palm Stearin is used moulding compounds and plasticine.
Hydrogenated Palm Stearin is used arious lubricants, hard consistency, and Pillar candles and candlesticks.
Hydrogenated Palm Stearin is sued crayons, coloured pencils, and waxing of surfaces.



PHYSICAL and CHEMICAL PROPERTIES of HYDROGENATED PALM STEARIN:
Physical Appearance: White Flakes
Colour in Gardner Scale: Maximum 3
Free Fatty Acid: Max 1 %
Iodine Value g/ 100 g: Max 3.0
Slip Melting Point Degree C: 58 – 60
Saponification Value Mg KOH/gm: 195 – 205



FIRST AID MEASURES of HYDROGENATED PALM STEARIN:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROGENATED PALM STEARIN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Pick up and arrange disposal without creating dust.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HYDROGENATED PALM STEARIN:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROGENATED PALM STEARIN:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROGENATED PALM STEARIN:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of HYDROGENATED PALM STEARIN:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


HYDROGENATED PALM STEARIN
Hydrogenated palm stearin is the solid fraction of palm oil that is produced by partial crystallization at controlled temperature.
Hydrogenated palm stearin is a stearin in the sense of stearins and oleins being the solid and liquid fractions respectively of fats and oils; not in the sense of glyceryl tristearate.
Hydrogenated palm stearin is more variable in composition than palm olein, the liquid fraction of palm oil, especially in terms of its solid fat content, and therefore has more variable physical characteristics.

CAS: 68514-74-9
EINECS: 271-056-3

Synonyms
Palm oil, hydrogenated;Oele, Palm-, hydriert;Akofine P;Akoflake Palm 58;Dub HPH;DUB-PPE 3;F 3 Oil;Grindsted PS 101

Hydrogenated palm stearin is a dietary supplement that can provide a number of health benefits.
Hydrogenated palm stearin is a rich source of essential fatty acids, which can help to reduce inflammation and improve cardiovascular health.
Hydrogenated palm stearin is also a good source of antioxidants, which can help to protect the body from free radical damage.
Additionally, Hydrogenated palm stearin can help to improve skin health, reduce cholesterol levels, and boost the immune system.
Hydrogenated palm stearin is the co-product of the palm oil refining process.
Hydrogenated palm stearin undergoes a hydrogenation process to become hydrogenated palm stearin.
The difference between Hydrogenated palm stearin and regular RBD palm stearin is the number of unsaturated chains of fatty acid molecules.

Hydrogenated palm stearin is known for its higher melting point than regular RBD palm stearin.
At normal temperature, Hydrogenated palm stearin appears white to a slightly yellow solid wax.
Hydrogenated palm stearin is insoluble in water, slightly soluble in gasoline, and soluble in acetone, benzol, chloroform, and alcohol.
Hydrogenated palm stearin in cosmetics is a derivative of palm oil subjected to hydrogenation, a process that solidifies the oil for enhanced stability and texture.
Hydrogenated palm stearin often appears as a creamy or solid substance and is widely used in skincare and beauty products for its emollient properties.
The chemical formula for Hydrogenated palm stearin involves adding hydrogen atoms to unsaturated palm oil, resulting in a more saturated and solid form.
While Hydrogenated palm stearin contributes to product texture, it is essential to note that the environmental impact of palm oil production, even in its modified forms, raises concerns due to deforestation and biodiversity loss.

Uses
Hydrogenated palm stearin is a useful source of natural hard vegetable fat for food applications.
Oils, palm, hydrogenated is a processed fat treated with hydrogen to extend shelf life and improve stability.
Hydrogenated palm stearin is an FDA-approved food additive and is often used as a dietary supplement in the food industry, often as a substitute for butter or other animal fats.
Hydrogenated palm stearin is also an ingredient in cosmetics.
Overview of palm oil in saturated fatty acids> 85%, unsaturated fatty acids <15%, the melting point of 24~41 deg C, the relative density of 0.925; Refined palm oil color yellowish, pure no smell.

This kind of palm oil because Hydrogenated palm stearin contains high melting point hard fat, melting speed is slow, greasy feeling, bad mouth, so it can only be used for the manufacture of low-grade soft ice cream.
However, the Hydrogenated palm stearin with a melting point of 32 ° C, which is obtained by separating and removing the high melting point hard fat and then carrying out partial hydrogenation, can be used for the production of soft ice cream, and obtain satisfactory results, but the cost is quite high.

Composition
Hydrogenated palm stearin consists of mostly glyceryl tripalmitate, with most of the rest of the fat content being glyceryl dipalmitate monooleate.
In terms of fatty acid composition, a typical soft palm stearin might contain almost 50% palmitic acid and 35% oleic acid.

Manufacturing Process
Hydrogenated palm stearin is obtained from fractionating RBD Palm Oil to separate olein from stearin.
Dry Fractionation: Hydrogenated palm stearin is a fully physical process.
Hydrogenated palm stearin does not require the use of any chemicals or additives so there is no yield loss and no contamination.
There are no chemical changes to RBD palm oil.
First, the Hydrogenated palm stearinis heated to approximately 70ºC and homogenized to fully melt the glycerides, and then hot and homogenized oil is allowed to cool in a controlled manner.
Chilled water is circulated for cooling purposes.
When the oil temperature reaches the desired cooling temperature, which depends upon the quality of Hydrogenated palm stearin, the cooling process is stopped.
The thick crystallized mass is filtered using a drum rotary filter and membrane filter to liquid RBD palm olein and solid Hydrogenated palm stearin.
Hydrogenated Palm Stearin
Polyisobutene 800;Butene, homopolymer, hydrogenated;Polybutene, hydrogenated;Polyisobutene, hydrogenated;isobutylene homopolymer, hydrogenated;Hydrogenated polyisobutylene cas no: 68937-10-0
HYDROGENATED POLYISOBUTENE
Hydrogenated Polyisobutene, Cas : 68937-10-0, EC : polymer, Butene, homopolymer, hydrogenated Polybutene, hydrogenated, hydrogenated polyisobutene
HYDROGENATED RAPESEED OIL
Nom INCI : HYDROGENATED SHEA BUTTER Classification : Huile hydrogénée Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
HYDROGENATED SHEA BUTTER
HYDROLYZED BEESWAX, N° CAS : 223705-74-6, Nom INCI : HYDROLYZED BEESWAX. Ses fonctions (INCI): Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion Agent stabilisant : Améliore les ingrédients ou la stabilité de la formulation et la durée de conservation Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
HYDROLITE 5
Hydrolite 5 is colorless liquid, practically odorless
Hydrolite 5 is a multifunctional cosmetic ingredient.


CAS Number: 5343-92-0
EC Number: 226-285-3
MDL number: MFCD00010736
Chemical Name: pentane-1,2-diol
INCI: Pentylene Glycol
Linear Formula: CH3CH2CH2CH(OH)CH2OH
Molecular Formula: C5H12O2



SYNONYMS:
1, 2-Dihydroxypentane, 1, 2-Pentylene glycol, 4-Methyl-1 2-butanediol, 1,2-pentanediol, 1,2-dihydroxypentane, 1,2-pentanediol, 2r, acmc-20mbh5, acmc-1axdb, 3-01-00-02191 beilstein handbook reference, ksc271i3n, wcvrqhfdjllwfe-uhfffaoysa, (±)-Pentane-1,2-diol, 1,2-Dihydroxypentane, 1,2-Pentylene Glycol, Diol PD, Hydrolite 5, NSC 513, (+/-)-Pentane-1,2-diol, 1,2-Dihydroxypentane, 1,2-Pentylene Glycol, Diol PD, Hydrolite 5, NSC 513, 1,2-Pentanediol, Pentane-1,2-diol, 5343-92-0, 1,2-Dihydroxypentane, NSC-513, 50C1307PZG, MFCD00010736, EINECS 226-285-3, BRN 1719151, UNII-50C1307PZG, AI3-03317, NSC 513, 1,a2-aPentanediol, EC 226-285-3, 1,2-Pentanediol, 96%, SCHEMBL62155, 3-01-00-02191 (Beilstein Handbook Reference), NSC513, WCVRQHFDJLLWFE-UHFFFAOYSA-, DTXSID10863522, PENTYLENE GLYCOL [WHO-DD], (+/-)-1,2-PENTANEDIOL, AKOS009156977, AS-40006, SY032914, CS-0017222, NS00001259, P1178, EN300-52018, A829586, Q3374899, InChI=1/C5H12O2/c1-2-3-5(7)4-6/h5-7H,2-4H2,1H3



Hydrolite 5 is a glycol derived from sugar cane with extreme hygroscopic properties and an anti-bacterial effect.
Hydrolite 5 is a multifunctional cosmetic ingredient.
Hydrolite 5 is a clear, colorless liquid of characteristic odor.


Hydrolite 5 is challenging the industry with over 5 key features boosting product efficiency.
Hydrolite 5 is pentylene glycol, a 1,2-alkanediol that revolutionised the market of cosmetic ingredients.


Hydrolite 5 hydrates skin and boosts the performance of active ingredients.
Following the motto ‘less is more’, Hydrolite 5 enhances modern recipes.
Hydrolite 5's multifunctional properties also benefit the solubilising and emulsifying characteristics of cosmetics ingredients with minimal effort.


Combined with antimicrobial agents, Hydrolite 5 supports modern product protection.
Hydrolite 5 is suitable for all skin types
Hydrolite 5 is manufactured from a raw material that is a by-product of sugar production and derived from sugar cane.


Hydrolite 5 meets the COSMOS standard.
Hydrolite 5 is a multi-functional cosmetic ingredient
Hydrolite 5 is a colorless liquid with a very low odor


Common name of Hydrolite 5 is 1,2-Pentanediol
Hydrolite 5 is soluble in water and cosmetic esters
Hydrolite 5 is globally approved


Recommended use level of Hydrolite 5 is 1 - 5%.
Hydrolite 5 is a high-performance hydration system designed for athletes and active individuals.
Hydrolite 5 provides superior hydration and electrolyte replenishment to support optimal performance during workouts and physical activities.


The green color indicates that Hydrolite 5 contains natural ingredients and is free from artificial additives.
Stay hydrated and energized with Hydrolite 5!
Hydrolite 5 green is a new generation of pentylene glycol.


Hydrolite 5 is made from sugar cane, COSMOS approved, Ecocert, Halal
Hydrolite 5 is colorless liquid, practically odorless
Recommended input percentage of Hydrolite 5 is up to 5.0%


Hydrolite 5 is soluble in both water and cosmetic ethers
Hydrolite 5 is stable and effective over a wide range of pH (3-12) and temperature
Hydrolite 5 is compatible with many cosmetics ingredients


Hydrolite 5 complies with Japanese Quasi-Drug Ingredients
Hydrolite 5 is used suitable for cosmetic and oral care products
Hydrolite 5 is 1,2-pentanediol.


Hydrolite 5 is a colourless liquid with a charateristic intrinsic odour.
Due to its chemical properties, Hydrolite 5 is readily soluble in water and oil
Hydrolite 5 hydrates the skin and boosts the efficacy of active ingredients used in cosmetic formulations.


In addition, Hydrolite 5 improves both the look and consistency, as well as the protection of the product.
Manufacturers of cosmetic products can use Hydrolite 5 in a wide range of cosmetics.
Hydrolite 5 enhances activity of actives.


Hydrolite 5 moisturises (humectant).
Hydrolite 5 improves stability of oil-in-water emulsions.
Hydrolite 5 improves solubility of ingredients and increases transparency.


Hydrolite 5 improves efficacy of preservatives (reducing their dosage).
Hydrolite 5 is sustainable pentylene glycol: 100% green carbon
Hydrolite 5 is patented process using raw materials from by-products : bagasse from sugar cane and pulp from wood.


Hydrolite 5 enhances the performances of active ingredients.
Hydrolite 5 is excellent moisturizer, also provides product protection.
Hydrolite 5 improves formula aesthetics including dispensability of pigments.


Hydrolite 5 stabilizes emulsions, excellent solvent and solubilizer.
Hydrolite 5 is solorless liquid, nearly odorless.
Hydrolite 5 is soluble in water, ethanol and glycols.


Hydrolite 5 is food grade - suitable for oral care.
Hydrolite 5 is COSMOS/Ecocert approved.
Hydrolite 5 represents the next generation of sustainable pentylene glycol!


100% bio-based carbon and COSMOS approved, Hydrolite 5 is made by a patented process from bagasse, a by-product coming from sugar cane which is ethically and responsibly sourced.
From classical to green formulations, from light to rich textures,


Hydrolite 5 is a sustainable (derived from sugar cane) version of the original pentylene glycol.
Hydrolite 5 enhances activity of actives.
Hydrolite 5 moisturises (humectant).


Hydrolite 5 improves stability of oil-in-water emulsions.
Hydrolite 5 improves solubility of ingredients and increases transparency.
Hydrolite 5 improves efficacy of preservatives (reducing their dosage).


pH Stability of Hydrolite 5 is 3-12 pH.
Hydrolite 5 acts as an excellent skin moisturizer.
Hydrolite 5 is clear, colorless liquid with very low odor soluble in water and cosmetic esters.


Hydrolite 5 reduces emulsion particle size to achieve better stability and improves formulation aesthetics.
Hydrolite 5 works synergistically with preservatives and enhances the bioavailability of cosmetic actives.
Hydrolite 5 possesses excellent safety profile.


Hydrolite 5 offers many hair care benefits and improves water-resistance of sunscreen formulations.
Hydrolite 5 is a true multifunctional.
Hydrolite 5 is made by a patented process from bagasse, a by-product coming from sugar cane, ethically and responsibly sourced.


In the context of increasing regulations, higher consumer expectations and escalating pressure on formulation cost, doing more with less is becoming an invitation to revisit the question of product protection - a perfect reason to discover (or rediscover), Hydrolite 5, a versatile 1,2-alkanediol with a long history of safe use and truly global compliance - USA, Europe, Japan (including quasi-drugs) and China.


Hydrolite 5 is a multifunctional ingredient derived from renewable raw materials from sugar cane.
Hydrolite 5 has the same properties as the original pentylene glycol.
Hydrolite 5 hydrates the skin and boosts the efficacy of active ingredients used in cosmetic formulations.


In addition, Hydrolite 5 improves both, the look and consistency as well as the protection of the product.
Hydrolite 5 can be used in a wide range of cosmetics.
Hydrolite 5 is 100% bio-based and COSMOS compliant.



USES and APPLICATIONS of HYDROLITE 5:
Application/Recommended of Hydrolite 5: Sun care (Sun protection, After-sun & Self-tanning), Toiletries (Shower & Bath, Oral care…) > Oral care, Skin care (Facial care, Facial cleansing, Body care, Baby care), Decorative cosmetics/Make-up, Hair care (Shampoos, Conditioners & Styling).
Recommended use levels of Hydrolite 5 is < 5.0 %.


Pentylene Glycol Biobased, also known as Hydrolite 5, is a versatile product widely used in various industries.
Hydrolite 5 serves as a multifunctional ingredient in personal care products, acting as a humectant, solvent, and preservative.
Its biobased nature makes Hydrolite 5 an environmentally friendly alternative to traditional petroleum-based glycols.


Hydrolite 5 finds applications in skincare, haircare, and cosmetic formulations, providing moisturizing and conditioning properties.
Additionally, Hydrolite 5 enhances the stability and shelf life of products, making it a valuable ingredient for manufacturers in the beauty and personal care industry.


Hydrolite 5 is used lotions, gels, creams, shampoos and emulsions.
Hydrolite 5 is used preservative-free preservation strategy option for some product types.
Hydrolite 5 is used in a variety of cosmetic and personal care products, such as moisturizers, body lotions, facial serums, body washes and shampoos, to provide long-lasting hydration to skin and hair.


Hydrolite 5 acts as a co-emulsifier reducing surface tension and particle size in emulsions thus providing better stability
Hydrolite 5 is an excellent solvent for ingredients such as perfumes
Increases the dispersion of pigments, improves the intensity and homogenization of color in make-up applications


Hydrolite 5 boosts skin hydration up to +10% after 4 hours of application, using a product with 3% Hydrolite 5 Green
Hydrolite 5 strengthens the antimicrobial protection of products because it acts synergistically with preservatives, thus providing excellent effectiveness
Hydrolite 5 enhances the performance of dihydroxyacetone ( DHA ) in self - tanning products and therefore improves natural tanning.


Hydrolite 5 is suitable for use in most types of formulations.
Hydrolite 5 is ecocert, Cosmos, Halal certified, biodegradable 88% in 28 days.
Hydrolite 5 enhances self-tanning: The properties of dihydroxyacetone (DHA) are enhanced.


The perception of Hydrolite 5 is also improved: durable, uniform color.Hydrolite 5 moisturizes the skin better than glycerin, reduces the stickiness of polymers, and helps introduce poorly soluble components into water.
Most importantly, Hydrolite 5 improves the transport of polar active ingredients across the lipid barrier.


The Hydrolite 5 molecule is both hydrophilic and lipophilic, and at the same time small.
It surrounds the active, forming a micelle, and conducts Hydrolite 5 through the lipid barrier.
As a result, the cosmetic product works more effectively.


The organoleptic properties of Hydrolite 5 create a wonderful feeling on the skin: light, yet nourishing and velvety.
By reducing surface tension Hydrolite 5 improves the aesthetics of the formulation and acts as a co- emulsifier. Ideal for “green” products and also enhances the naturalness of classic recipes.


Hydrolite 5, also known as pentylene glycol, is a plant-based humectant that helps retain moisture in the skin and keep it hydrated.
Hydrolite 5 is a sustainable and environmentally friendly alternative to other synthetic moisturizers.
This a multifunctional ingredient, Hydrolite 5, that can be used in a diverse range of cosmetics for a range of applications.


These include; improving active efficacy, skin hydration, improves stability/solubility of ingredients and improving the efficacy of preservatives.
Hydrolite 5 is the ideal multifunctional ingredient that increases the performance of active ingredients, moisturizes the skin, bring benefits in hair care, improves the sensorial profile of formulas and enhances product protection


This a multifunctional ingredient, Hydrolite 5, that can be used in a diverse range of cosmetics for a range of applications.
These include; improving active efficacy, skin hydration, improves stability/solubility of ingredients and improving the efficacy of preservatives.
Microbes need water to be available to them so that they can thrive.


Humectants such as Hydrolite 5 capture and lock-up a formulations free water thus rendering the formulation environment stressful for microbes.
In some cases such as simple creams, spritzers and cleansers this can be used as the sole preservative if added at 4-5%.
In more challenging formulations such as those with lots of herbal extracts, clays or colours, the water-binding strategy may be too slow to knock-down the initial micro load and so may not be suitable.


A humectancy approach to product preservation, where free water is bound up is one of the healthiest strategies for the microbiome as Hydrolite 5 has no negative effect on the skins natural flora.
However, Hydrolite 5 is worth noting that the only way of assuring your product is protected is by investing in micro testing.


Hydrolite 5 has obtained the COSMOS natural raw material certification.
The natural raw materials used are internationally recognized.
Hydrolite 5's antibacterial properties are mild and safe, with minimal skin irritation.


Hydrolite 5 also does not contain potentially irritating short-chain unsaturated fatty acids, 1 ,2 Epoxypentane, peroxide, etc.
Hydrolite 5 contains both hydrophilic and lipophilic groups, which means it can be soluble in water and many oils, so it can be used as a good solvent in skin care products and cosmetic raw materials.


When used in serum or serum, Hydrolite 5 can help enhance the transparency of the system.
Since Hydrolite 5 can be dissolved in many oils, it can be used as a natural moisturizer in cosmetics with water-free formulas.
When used in sunscreen products, Hydrolite 5 helps to improve the water resistance of the product.


Hydrolite 5 is often used in preservative-free skin creams, eye creams, skin lotions, and baby care products.
Hydrolite 5 is especially suitable for sensitive skin, delicate skin such as infants and young children, and aging Care for dry skin.
Using Hydrolite 5 alone and adding 3% to 5% is enough to meet the application needs of skin care products and cosmetics without preservatives.


Hydrolite 5 can be stored at room temperature for up to 6 months.
Of course, the shorter the time after use, the better.
Effective antibacterial activity applies to a wide pH range of 3~12pH.


If you need a longer storage time, it is recommended to add 1% phenoxyethanol antibacterial agent (Phenoxyethanol) at the same time, which will have a synergistic effect.


Hydrolite 5 is the ideal multifunctional ingredient that moisturizes the skin, brings benefits in hair care, increases the performance of cosmetic ingredients, improves the sensorial profile of formulas and enhances product protection, while respecting the skin microbiome. 100% bio-based and COSMOS approved, Hydrolite 5 is derived from sugar cane and wood (ethically & responsibly sourced).


From classical to green formulations, from light to rich textures, Hydrolite 5 is the ideal multifunctional for any type of skin.
Hydrolite 5 hydrates the skin and boosts the efficacy of active ingredients used in cosmetic formulations.



WHERE IS HYDROLITE 5 USED?
Hydrolite 5 belongs to the group of hydroxyl group-containing substances such as ethanol, glycerol and sorbitol.
Hydrolite 5 is a colorless and viscous liquid that is miscible with water and has a boiling point of 242 degrees Celsius.

Hydrolite 5 is increasingly used in cosmetic products these days, although there are many other uses.
For example, Hydrolite 5 is widely used as a solvent and as a plasticizer in the plastics industry.
Hydrolite 5 is also frequently integrated into cleaning products.

Hydrolite 5 has both moisture-binding and antimicrobial properties.
As a dihydric alcohol, in a certain concentration Hydrolite 5 prevents undesirable microorganisms from multiplying.



WHAT ARE THE POSITIVE PROPERTIES OF HYDROLITE 5 IN COSMETICS?
Hydrolite 5 on the other hand, is classified neither as hazardous to health nor as toxic, since the substance cannot be detected in urine or human tissue.
Hydrolite 5 is therefore considered to be harmless.

Thanks to Hydrolite 5's very good tolerability, skin sensitization is also virtually ruled out.
Another immensely important advantage of Hydrolite 5 is that, in contrast to conventional alcohol, it does not have a drying effect even at higher dosages.
Hydrolite 5 also has a positive effect on the stability as well as on the haptic properties of various emulsions by influencing the droplet size.



FUNCTIONS OF HYDROLITE 5:
*Skin conditioning
*Solvent



BENEFITS OF HYDROLITE 5:
*Hydrolite 5 reduces emulsion particle size: helps achieve better stability and improves formulation aesthetics
*Excellent solvent, especially for ingredients that are hard to dissolve
*Aid to enhance bio availability of actives
*Broad spectrum anti-microbial activity: works synergistically with preservatives
*Hydrolite 5 improves water-resistance of sunscreen formulations
*Beneficial for hair care formulations
*Excellent safety profile



MORE THAN 6 SUBSTANTIATED KEY BENEFITS OF HYDROLITE 5:
Hydrolite 5 is challenging the definition of multifunctionality with over 6 key features promoting product efficiency:

1. Efficacy enhancer
2. Moisturizer
3. Haircare performance
4. Formulation esthetics
5. Emulsion stability
6. Product protection

Hydrolite 5 also improves pigment dispersion, helps to get whiter and shinier emulsions, facilitates absorption on to the skin and enhances the efficacy of cooling agents.
All these properties delivered by a molecule stable at a wide pH range (3-12) and at high temperatures.



BENEFITS OF HYDROLITE 5:
· Excellent skin moisturizer
· Reduces emulsion particle size: helps achieve better stability and improves formulation aesthetics
· Works synergistically with preservatives
· Enhances the bioavailability of cosmetic actives
· Improves water-resistance of sunscreen formulations
· Many hair care benefits
· Excellent safety profile



FEATURES OF HYDROLITE 5:
• Plant-derived alkanediol
• Highly moisturizing and has a broad antibacterial spectrum
• Improves pigment dispersion
• Makes emulsion particles smaller
• Non-tacky, humectant, booster
• Excellent solubilizer
• Emulsion stabilizer
• Bioavailability enhancer
• Improves formulation aesthetics



COSMETIC EFFECTS OF HYDROLITE 5:
- enhances the effect of active ingredients
- moisturizes the skin (+ 10% to hydration when adding 3% Hydrolite 5)
- improves the sensory characteristics of formulations
- improves the aesthetics of the final product
- Hydrolite 5 improves the intensity and uniformity of color in decorative cosmetics
- increases the microbiological properties protection
- co-emulsifier
- reduces the stickiness of polymers in the formulation
- creates a velvety light feel in the formulation
- Hydrolite 5 enhances the active effect of the hydrophilic antioxidant carnosine, increasing its bioavailability. (this antioxidant is found, for example, in co2 extract of rosemary or sage
- By reducing the dosage of the active ingredient, Hydrolite 5 helps reduce costs



KEY FEATURES OF HYDROLITE 5:
- 100% bio-based carbon
- COSMOS approved
- Naturalness Index: 1
- Origin: sugar cane
- Using the bagasse (a by-product of sugar production)



CLAIMS OF HYDROLITE 5:
*Antimicrobials
*Moisturizing Agents
*water-resistant / waterproof
*moisturizing
*Thickeners & Stabilizers
*Moisturizing Agents
*protections
*bio/ organic



PROPERTIES OF HYDROLITE 5:
Hydrolite 5 is multifunctional in a cosmetic product, since it: - Improves the skin's ability to retain water by increasing its hydration by 10% (3%, one application to 13 volunteers - hand gel, counting after 1, 2, 3 and 4 hours) -
Hydrolite 5 has antimicrobial properties -

Hydrolite 5 acts as a solvent - Improves the texture of emulsions and stabilizes them by reducing the size of the fat droplets in them.
Hydrolite 5 is stable in cosmetic products whose pH is between 3.0-12.0
Hydrolite 5 remains stable when stored in a closed, light-protected container in a cool, dry place.



FUNCTIONS OF HYDROLITE 5:
*Skin conditioning
*Solvent



DOSAGE OF HYDROLITE 5:
The dosage of Hydrolite 5 may vary depending on the specific formulation of the product.
Hydrolite 5 is typically used in concentrations ranging from 1% to 5% in skin and hair care products.



PRECAUTIONS OF HYDROLITE 5:
Hydrolite 5n is considered safe for use in cosmetics, but it is recommended to follow the manufacturer's recommended dosage guidelines and perform patch tests before using it on large areas of skin to avoid possible allergic reactions or irritation.



FUNCTIONS OF HYDROLITE 5:
Humectant, antimicrobial, solubilises fragrances, reduces the surface tension of water, improves the antioxidant effect, improves the colour in coloured products, increases the permeability of the skin which makes the active ingredients penetrate better.



PHYSICAL and CHEMICAL PROPERTIES of HYDROLITE 5:
Molecular Weight: 104.15 g/mol
XLogP3-AA: 0.2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 3
Exact Mass: 104.083729621 g/mol
Monoisotopic Mass: 104.083729621 g/mol
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 7
Formal Charge: 0
Complexity: 37.1

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular Formula: C5H12O2
Molecular Weight: 104.149 g/mol
SMILES: CCCC(O)CO

CAS Number: 5343-92-0
InChI: InChI=1/C5H12O2/c1-2-3-5(7)4-6/h5-7H,2-4H2,1H3
InChI Key: WCVRQHFDJLLWFE-UHFFFAOYSA-N
MDL Number: MFCD00010736
Density: 0.9710 g/mL
Flash Point: 105°C
Assay Percent Range: 95% min. (GC)
Linear Formula: CH3(CH2)2CH(OH)CH2OH
Specific Gravity: 0.971
Solubility Information: Solubility in water: miscible
Physical Form: Liquid

CAS Min %: 96.0
Color: Colorless to Yellow
Boiling Point: 206.0°C
Infrared Spectrum: Authentic
Refractive Index: 1.4387 to 1.4407
Beilstein: 01,II,548
IUPAC Name: pentane-1,2-diol
PubChem CID: 93000
Percent Purity: 96%
Chemical Name or Material: 1,2-Pentanediol, 97%



FIRST AID MEASURES of HYDROLITE 5:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Remove contact lenses.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROLITE 5:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROLITE 5:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROLITE 5:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROLITE 5:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROLITE 5:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available

HYDROLITE 6
Hydrolite 6 is clear, non-tacky liquid, suitable for sensitive skin.
Hydrolite 6 is a versatile 1,2-Alkanediol.


CAS Number: 6920-22-5
EC Number: 230-029-6
MDL number: MFCD00010737
INCI Name: 1,2-HEXANEDIOL
Chemical Composition: 1,2-alkanediol
Linear Formula: CH3(CH2)3CH(OH)CH2OH
Molecular formula: C6H14O2



SYNONYMS:
1,2-Hexanediol, 6920-22-5, hexane-1,2-diol, DL-1,2-Hexanediol, 1,2-Dihydroxyhexane, 5,6-Dihydroxyhexane, dl-hexane-1,2-diol, MFCD00010737, TR046Y3K1G, UNII-TR046Y3K1G, (+/-)-Hexane-1,2-diol, 1,2-Dihydroxyhexane, 1,2-Hexyleneglycol, 5,6-Dihydroxyhexane, DL-1,2-Hexanediol, KMO 6, EINECS 230-029-6, 1,2-Hexylene Glycol, AI3-13210, 1,2-Hexanediol, 98%, EC 230-029-6, SCHEMBL53705, 1,2-HEXANEDIOL, DL, DTXSID40863959, AMY11157, AKOS015915402, CS-W013596, DB14108, DS-7407, PD085650, SY049796, 2,2,6,6-Tetrakis(hydroxymEt)cyclohexanol, H0688, NS00009391, F11270, EN300-1678327, J-800310, W-104641, Q27290177, 1,2-Dihydroxyhexane, 1,2-Hexyleneglycol, 5,6-Dihydroxyhexane, DL-1,2-Hexanediol, Dermasoft Hexiol, DL-hexane-1,2-diol, Purolan® HD-LO



Hydrolite 6 is a colorless liquid with hygroscopic nature.
Hydrolite 6 is ideal for use as an emollient, humectant, and wetting agent in cosmetic and skin care products.
Hydrolite 6 is broad-spectrum, water-soluble, preservative booster.


Hydrolite 6 is good solvent.
Hydrolite 6 is clear, non-tacky liquid, suitable for sensitive skin.
Hydrolite 6 is a versatile 1,2-Alkanediol.


Hydrolite 6 is stable at high, low pH and high temperature.
Hydrolite 6 helps to reduce or eliminate preservatives like parabens, formaldehyde donors or phenoxyethanol.
Hydrolite 6 can be combined with low doses of preservatives like phenoxyethanol & acid based preservatives such as sorbate, benzoate and dehydroacetate, for effective preservation of personal care formulations.


Hydrolite 6 is mild and perfectly suitable for sensitive skin applications.
Hydrolite 6 additionally helps to solubilise lipophilic cosmetic ingredients, improve the sensory profile of formulations, stabilise emulsions (due to its smaller droplet sizes) and enhance product protection.


Hydrolite 6 is a high quality, 100% nature-derived version of 1,2-hexanediol, a liquid multifunctional ingredient for cosmetics.
Hydrolite 6 will moisturize the skin, improve the sensory profile of formulations, stabilize emulsions, help solubilize other ingredients, and enhance product protection.


Hydrolite 6 with good water solubility is compatible with all formulation types.
Hydrolite 6 is a colourless to light yellow liquid with a
characteristic intrinsic odour.


Due to its chemical properties, Hydrolite 6 is readily soluble in water and oil.
Hydrolite 6 is a high purity 1,2-Hexanediol that can be used in personal care formulations not only as a humectant, but also as a safe substitute of traditional preservatives.


Hydrolite 6 has a broad anti-microbial ability with limited endocrine disrupting effect.
Manufacturing of Hydrolite 6 involves processes of reducing the undesirable odor of 1,2-Hexanediol and bringing the purity up to min 99.5%.
Hydrolite 6 is a very famous moisturising agent, being used for its silky touch in baby care.


Hydrolite 6 would also be efficient to increase skin’s moisture content.
Nearly odourless and colourless, Hydrolite 6 is suitable for most cosmetic systems and complies with US, European Union (including Danish), Japanese and Chinese regulations.


Hydrolite 6 stabilizes emulsions and is an excellent solvent.
Hydrolite 6 is suitable for use in the field of oral care.
Hydrolite 6 is a moisturizing agent.


Hydrolite 6 is also known by other names such as hexane-1,2-diol and 1,2-Dihydroxyhexane.
Hydrolite 6 is glycol alcohol (with two hydroxy groups on 1 and 2 positions and six carbon atoms), a multifunctional ingredient used as a solvent, emollient, moisturizing agent, and preservative in skin and hair care applications.


Hydrolite 6 is a clear, colorless hygroscopic liquid with a good humectant effect and spreadability.
Hydrolite 6 is freely soluble in water and can easily be incorporated into formulation.
Hydrolite 6 is nearly odorless.


Hydrolite 6 is an alcohol that belongs to the diol or glycol family.
This organic chemical ingredient, Hydrolite 6, contains two hydroxyl groups (-OH) and six carbon atoms.
Hydrolite 6 functions both as a solvent and a cosurfactant, enhancing the effectiveness of surfactants.


These can act as foaming agents, emulsifiers, detergents, dispersants, and wetting agents in a variety of skincare products.
Hydrolite 6's chemical formula is C6H14O2.
Hydrolite 6 also shows interesting properties to boost the antimicrobial efficacy of many common preservatives.



USES and APPLICATIONS of HYDROLITE 6:
This liquid water-soluble multifunctional ingredient, Hydrolite 6, acts as an emollient, a moisturizer, and a solubilizer, and improves formulation esthetics and sensorial profile.
Hydrolite 6 also helps to protect formulations as it supports the efficacy of cosmetic product protection systems.


Hydrolite 6 is also known for its mildness, which makes it suitable for all skin types, even the most delicate ones.
Hydrolite 6 acts as a multifunctional moisturizer and product protection enhancer.
Hydrolite 6 stabilizes the foam of surfactant solutions.


Hydrolite 6 is compatible with most anionic-, non-ionic & amphoteric cosmetic systems and formulation types.
Hydrolite 6 can go into conventional and green formulations and all formulation types.
Its exceptional mildness makes Hydrolite 6 compatible with all skin types, even the most delicate ones.


Hydrolite 6 represents a family of multifunctionals with particularly robust stability, safety, and versatility.
As product protection enhancers, Hydrolite 6 has become essential components of modern product protection systems.
The industry has used traditional Hydrolite 6 for decades, particularly for product protection.


Hydrolite 6 now enters the cosmetic market as the first completely green variant.
Hydrolite 6 is designed for use in conventional and green formulations and all formulation types.
Hydrolite 6 is a moisture-binding ingredient that has been scientifically proven as beneficial for the skin and hair, according to SpecialChem.


Hydrolite 6 is used in a wide range of products all across the cosmetic industry, such as cleansing and bath products.
Hydrolite 6 meets [quality and sustainability] requirements by combining high purity, multiple benefits and [environmentally] sustainable raw material source.


Hydrolite 6 moisturizes the skin.
Hydrolite 6 helps to solubilize lipophilic cosmetic ingredients.
Hydrolite 6 improves the sensory profile of formulations;


Hydrolite 6 stabilizes emulsions due to smaller droplet sizes and enhances product protection.
Hydrolite 6 can go into all formulation types and is compatible with all skin types.
Hydrolite 6 can be used in conventional and green formulations and all formulation types.


Its exceptional mildness makes Hydrolite 6 compatible with all skin types, even the most delicate ones.
Hydrolite 6 boosts the preservative efficacy of mild organic acids such as potassium sorbate and dehydroacetate, thus making the use of parabens and other controversial preservatives unnecessary.


Hydrolite 6 therefore offers an interesting alternative to manufacturers of skin care products for children, in a context where Danish authorities have banned propyl and butyl paraben in cosmetic products for children under the age of three, and where consumers increasingly favour natural and preservative-free products.


Hydrolite 6 is a synthetic preservative, solvent and moisture-binding agent.
Its primary action as a preservative is against bacteria, not molds or fungi, so Hydrolite 6 would never be used as the sole preservative in a water-based formula.


Because of its low molecular weight chemical structure, Hydrolite 6 is highly water soluble and can also help improve the efficacy of other preservatives.
Hydrolite 6 also has texture-enhancing and wetting properties when used in higher amounts, helping to create smooth-flowing gels and serums.
Usage levels of Hydrolite 6 in cosmetics ranges from 0.5–3%.


Hydrolite 6’s supplied as a colorless liquid.
Hydrolite 6 has been reviewed by the Expert Panel for Cosmetic Ingredient Safety.
The Expert Panel concluded that Hydrolite 6 is safe as used in cosmetics and personal care products.


Hydrolite 6 is considered non-sensitizing.
Hydrolite 6 is one of the most multi-functional ingredients in the cosmetic industry.
Hydrolite 6 is used in skin care, hair care as well as beauty products.


Hydrolite 6 is a great emollient as well as a humectant, that is, it preserves hydration on the skin while also softening it.
Not just this, Hydrolite 6 also acts as a preservative.
Hydrolite 6 prevents bacterial growth in the formulations that it is used in, thus increasing the overall shelf life.


Hydrolite 6 can undergo ruthenium-hydride catalyzed dehydrative coupling with anilines to form substituted indole and quinoline products.
A really multi-functional helper ingredient that can do several things in a skincare product: Hydrolite 6 can bring a soft and pleasant feel to the formula, it can act as a humectant and emollient.


Hydrolite 6 can be a solvent for some other ingredients (for example it can help to stabilize perfumes in watery products) and it can also help to disperse pigments more evenly in makeup products.
And that is still not all: Hydrolite 6 can also boost the antimicrobial activity of preservatives.


Therefore, Hydrolite 6 is suitable in particular for formulations with no or low fragrance content.
Suspending microbial growth, Hydrolite 6 is an ecologically friendly preservative and booster for other preservatives.
Used as an emollient, Hydrolite 6 stabilizes emulsions while helping solubilize other active ingredients.


In decorative cosmetics and anhydrous formulas, Hydrolite 6 is used for pigment wetting, control of viscosity, and stickiness.
Thanks to compatibility with a wide range of ingredients, Hydrolite 6 is readily incorporated into the formulations, working well with surfactants, oils, and violate compounds, improving sensation, consistency, and penetration.


Hydrolite 6 exhibits good compatibility with skin (losest irritation or sensibilization), excellent biological degradation profile, and antioxidant boosting effect.
This diol is found in Hydrolite 6's application in many cleansers, creams, lotions, masks, hair care, and sensitive skin care products.


Hydrolite 6 is a multi-functional ingredient used in the cosmetic industry.
Hydrolite 6 acts as a great humectant, preserving hydration on the skin while also softening it.
Hydrolite 6 also acts as a preservative, preventing bacterial growth in the formulations that it is used in, thus increasing the overall shelf life.


Recent studies have shown that Hydrolite 6 has anti-inflammatory properties, making it an ideal ingredient for those with sensitive or acne-prone skin.
Hydrolite 6's ability to reduce inflammation can help to calm irritated skin and reduce the appearance of redness and blemishes.
Hydrolite 6 acts as cosurfactant, used for modifying the sodium dodecyl sulfate micelles.


Solubility of Hydrolite 6 in supercritical CO2 has been reported.
Hydrolite 6 has a tendency of self-association to form micelle-like aggregates.
Hydrolite 6 can be used in the ruthenium-catalyzed synthesis of oxazolidin-2-ones from urea.



WHAT IS HYDROLITE 6 USED FOR?
Hydrolite 6 is a moisture-binding ingredient that has proven to be beneficial for the skin and hair in more than one way.
Hydrolite 6 is used in a wide range of products all across the cosmetic industry such as cleansing and bath products.

*Skin care:
Hydrolite 6 is an amazing ingredient for extremely dry and flaky skin. Hydrolite 6 holds moisture on the topmost layers of the skin and keeps it hydrated.
This makes Hydrolite 6 a really effective humectant that is used in skin care products such as moisturizers and lotions

*Hair care:
Hydrolite 6 aids in smooth and detangled hair because of the high hydration that it provides.
Hydrolite 6 is a popular choice in hair care products as it can help disperse a lot of hair problems

*Cosmetic products:
Hydrolite 6 acts as a superb preservative - increasing the shelf life of products.
Hydrolite 6 stops bacterial formation in formulations.
Furthermore, Hydrolite 6 is also a solvent that dissolves other ingredients and helps them spread out evenly in the product.



ORIGIN OF HYDROLITE 6:
Hydrolite 6 is a synthetic ingredient that is made up of many chemicals such as diosgenin, chrysin, and alpha-lipoic acid.
These chemicals are good for skin and hair, and impart various beneficial properties to Hydrolite 6 like anti-inflammation and the qualities of a preservative.



WHAT DOES HYDROLITE 6 DO IN A FORMULATION?
*Emollient
*Hair conditioning
*Humectant
*Preservative
*Smoothing
*Solvent



SAFETY PROFILE OF HYDROLITE 6:
Hydrolite 6 is safe for skin and hair when used in lower concentrations.
A patch test is recommended prior to full application especially for people having highly sensitive skin.



ALTERNATIVES OF HYDROLITE 6:
*PENTYLENE GLYCOL,
*CAPRYLYL GLYCOL



FUNCTIONS OF HYDROLITE 6:
*Skin conditioning :
Hydrolite 6 maintains skin in good condition
*Solvent :
Hydrolite 6 dissolves other substances



CLAIMS OF HYDROLITE 6:
*Antimicrobials
*Moisturizing Agents
*protections
*mildness
*moisturizing



FUNCTIONS OF HYDROLITE 6:
*Humectant
*Emollient
*Solvent
*Preservative booster
*Skin conditioning



BENEFITS OF HYDROLITE 6:
*Hydration



CATEGORIES OF HYDROLITE 6:
*Preservative,
*Humectant,
*Solvent,
*Texture Enhancer



HYDROLITE 6 AT A GLANCE:
*Synthetic multi-tasking ingredient
*Works as a preservative, solvent, humectant, and texture enhancer
*Active against bacteria, not molds or fungi
*Considered non-sensitizing in amounts used in cosmetics



FUNCTIONS OF HYDROLITE 6 IN COSMETIC PRODUCTS:
*SKIN CONDITIONING
Hydrolite 6 maintains the skin in good condition

*SOLVENT
Hydrolite 6 dissolves other substances



ADVANTAGES OF HYDROLITE 6:
Hydrolite 6 offers numerous advantages
— The industry has used traditional Hydrolite 6 for decades, particularly for product protection.
— Hydrolite 6 now enters the cosmetic market as the first completely green variant.
— Hydrolite 6 comes with the following characteristics:
— Efficiently moisturizes the skin
— Helps to solubilize lipophilic cosmetic ingredients
— Improves the sensory profile of formulations
— Stabilizes emulsions due to smaller droplet sizes
— Enhances product protection



PHYSICAL and CHEMICAL PROPERTIES of HYDROLITE 6:
Physical Properties:
Appearance: colorless clear liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.95100 @ 25.00 °C
Refractive Index: 1.44200 @ 20.00 °C
Boiling Point: 223.00 to 224.00 °C @ 760.00 mm Hg
Vapor Pressure: 0.019000 mmHg @ 25.00 °C (est)
Flash Point: > 230.00 °F TCC (> 110.00 °C)
logP (o/w): 0.520 (est)
Shelf Life: 24.00 month(s) or longer if stored properly
Storage: store in cool, dry place in tightly sealed containers,
protected from heat and light

Soluble in: alcohol, water, water, 2.617e+004 mg/L @ 25 °C (est)
CAS Number: 6920-22-5
Molecular Weight: 118.17
Beilstein: 1719244
EC Number: 230-029-6
MDL number: MFCD00010737
Boiling Point: 223-224 °C
Melting Point: 2.0 °C
Solubility: Miscible in water
Molecular Weight: 118.17 g/mol
XLogP3-AA: 0.7
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2

Rotatable Bond Count: 4
Exact Mass: 118.099379685 g/mol
Monoisotopic Mass: 118.099379685 g/mol
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 45.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of HYDROLITE 6:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Remove contact lenses.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROLITE 6:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROLITE 6:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROLITE 6:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROLITE 6:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROLITE 6:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available

HYDROLITE CG
Hydrolite CG has good moisturizing properties.
Hydrolite CG also supports the efficacy of cosmetic preservative systems.


CAS Number : 1117-86-8
EC Number: 214-254-7
MDL number: MFCD00010738
INCI Name: Caprylyl Glycol
Chemical Composition: 1,2-Octandiol
Linear Formula: CH3(CH2)5CH(OH)CH2OH
Molecular formula: C8H18O2



SYNONYMS:
1,2-OCTANEDIOL, 1117-86-8, octane-1,2-diol, 1,2-Dihydroxyoctane, caprylyl glycol, 1,2-Octylene glycol, DTXSID9036646, CHEBI:34056, 00YIU5438U, MFCD00010738, NSC-71546, Dermosoft Octiol, LexGard O, CAPRYL GLYCOL, UNII-00YIU5438U, EINECS 214-254-7, NSC 71546, JEECIDE CAP, ORISTAR CPG, racemic 1,2-octanediol, AI3-13058, 1,2-Octanediol, 98%, EC 214-254-7, NCIOpen2_000498, SCHEMBL62856, CHEMBL3186864, DTXCID7016646, 1,2-OCTANEDIOL [WHO-DD], BCP32882, NSC71546, Tox21_301019, LMFA05000089, (+/-)-OCTANE-1,2-DIOL, AKOS015837551, 1,2-Octylene glycol;Octane-1,2-diol, CS-W018222, DB14589, SB45338, NCGC00248257-01, NCGC00254921-01, AS-17606, SY031445, CAS-1117-86-8, DB-027314, NS00010217, O0277, F21409, O-0990, 1,2-Octanediol, Vetec(TM) reagent grade, 98%, A802412, J-640303, J-660007, Q27115777, 1,2-DIHYDROXYOCTANE, 1,2-OCTANEDIOL, Octane-1,2-diol, (R,S)-Octane-1,2-diol, 1,2-0ctanediol, 1,2-Octandiol, 1,2-Octylene glycol, 1,2-Octyleneglycol, 7,8-Dihydroxyoctane, n-Octane-1,2-diol, octane-1, R,S-Octane-1,2-diol, 1,2-Octanediol (NODiol), CAPRYLYL GLYCOL, 1,2-OCTANEDIOL, 98+%, Octan-1,2-diol, 1,2-Octanediol, GC 98%, 1,2-OCTANEDIOL 96+%, 1,2-OCTANEDIOL 98.5%, 1,2-Dihydroxyoctane, 1,2-Octylene glycol, octane-1,2-diol, CAPRYLYL GLYCOL,Octane-1,2-diol,1,2-DIHYDROXYOCTANE,octane-1,,1,2-Octandiol,Octan-1,2-diol,1,2-OCTANEDIOL,1,2-OCLanediol,1,2-0ctanediol,n-Octane-1,2-diol, Octane-1,2-diol, 1,2-Octanediol, Caprylyl glycol, Glycol caprylyl, 1,2-Dihydroxyoctane, 1,2-Octylene glycol,



Hydrolite CG, 1,2-Octanediol, is a multi-functional moisturizing ingredient.
Hydrolite CG supports the efficacy of cosmetic preservative systems while reducing and/or eliminating the need for parabens, isothiazolinones and Phenoxyethanol.


Hydrolite CG is a multifunctional ingredient that acts as an emollient, a moisturizer, a pigment dispersant, and a viscosity regulator.
Hydrolite CG also helps to protect formulations as it supports the efficacy of cosmetic product protection systems.
Hydrolite CG is 1,2-Octandiol, a multi-functional moisturizing
ingredient.


Hydrolite CG is a cosmetic Raw Material.
This new grade of caprylyl glycol offers all the properties, benefits, and high quality of the synthetic grade, Hydrolite CG with a greater degree of sustainability due to its 100% biobased sourcing.


Hydrolite CG has good moisturizing properties.
Hydrolite CG also supports the efficacy of cosmetic preservative systems.
Hydrolite CG is used hair and skin cosmetics


Hydrolite CG brings many benefits for formulations, such as moisturising as well as antioxidant properties and achieve full product protection by maintaining the microbiome.
Hydrolite CG is a excellent preservative booster


Hydrolite CG combines well with low levels of preservatives for broad-spectrum protection
Hydrolite CG is excellent for emulsion and anhydrous products
Hydrolite CG is stable at high/low pH and high temperature.


Hydrolite CG helps reduce or eliminate preservatives like parabens, formaldehyde donors or phenoxyethanol.
Hydrolite CG can be combined with low doses of preservatives like phenoxyethanol and acid-based preservatives like sorbate, benzoate and dehydroacetate for effective preservation of personal care formulations.


Hydrolite CG is 100% biodegradable and GMO-free.
Hydrolite CG is Halal and Kosher certified.
Hydrolite CG is a colorless to white low melting solid.


Hydrolite CG is a potential pediculicide and is useful for treating head louse infestation clinically.
Hydrolite CG is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Hydrolite CG is a compound used in preparation of halohydrin palmitates.
Hydrolite CG, also known as caprylyl glycol, is a diol with the molecular formula CH3(CH2)5CHOHCH2OH.
Hydrolite CG is an octanediol.



USES and APPLICATIONS of HYDROLITE CG:
Hydrolite CG is also used in coating materials, slurries, paper mills and water circulation systems for the effective preservation against bacteria and fungi.
Hydrolite CG is used as an emollient, humectant, and wetting agent in cosmetic and skin care products.


Hydrolite CG is an emollient with moisturizing properties that may also be used as a cosmetic stabilizer.
When found in combination with phenoxyethanol these two ingredients work together as an anti-microbial.
Hydrolite CG is a novel surfactant used in the treatment of head louse.


Hydrolite CG is also used in the cosmetics industry in the formulations of sunscreen gels and eye make-up.
Hydrolite CG has a variety of applications.
Hydrolite CG is used to improve HPLC separation of organic acids and bases and to synthesize halohydrin palmitates.


Additionally, Hydrolite CG is studied for its potential use as a pediculicide and has been shown to be effective against louse infestations.
Hydrolite CG is a common component of many creams and ointments, where it is used as a skin conditioning agent.
Hydrolite CG is also noted to have some antimicrobial (preserving) ability.


Hydrolite CG is used in cosmetics, moisturizer with antibacterial activity.
Hydrolite CG is used in bath and shampoo products, with thickening and foam stabilizing effects.
Hydrolite CG was used as organic modifier to improve the HPLC separation of organic acids and bases.


Hydrolite CG was also used in preparation of halohydrin palmitates.
Hydrolite CG is categorized as a diol and aliphatic alcohol, indicating its origin from a hydrocarbon.
Hydrolite CG plays a role in the synthesis of various organic compounds, including polyurethanes, polyesters, and polyamides.


Hydrolite CG is a compound used in preparation of halohydrin palmitates.
Hydrolite CG is used in the following products: cosmetics and personal care products, pharmaceuticals, perfumes and fragrances, biocides (e.g. disinfectants, pest control products) and laboratory chemicals.


Hydrolite CG is used for the manufacture of: chemicals and .
Other release to the environment of Hydrolite CG is likely to occur from: indoor use as processing aid.
Hydrolite CG is used in the following products: cosmetics and personal care products, pharmaceuticals, perfumes and fragrances and inks and toners.


Release to the environment of Hydrolite CG can occur from industrial use: formulation of mixtures.
Hydrolite CG is used in the following products: cosmetics and personal care products and pharmaceuticals.
Hydrolite CG is used in the following areas: health services.


Hydrolite CG is used for the manufacture of: chemicals.
Release to the environment of Hydrolite CG can occur from industrial use: in processing aids at industrial sites and as an intermediate step in further manufacturing of another substance (use of intermediates).


Hydrolite CG is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Hydrolite CG is used in the following products: washing & cleaning products, cosmetics and personal care products, biocides (e.g. disinfectants, pest control products), perfumes and fragrances, pharmaceuticals, air care products and polishes and waxes.


Release to the environment of Hydrolite CG can occur from industrial use: manufacturing of the substance.
Other release to the environment of Hydrolite CG is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Hydrolite CG is recommended for hair and skin care applications.


Hydrolite CG also helps to protect formulations as it supports the efficacy of cosmetic product protection systems.
Hydrolite CG supports the efficacy of cosmetic preservative systems while reducing and/or eliminating the need for parabens, isothiazolinones and Phenoxyethanol.


Cosmetic Uses of Hydrolite CG: hair conditioning, humectants, skin conditioning, and skin conditioning - emollient.
Hydrolite CG is 1,2-Octandiol, a multifunctional ingredient, that acts as an emollient and a moisturizer.
Hydrolite CG also helps to protect formulations as it supports the efficacy of cosmetic product protection systems.


Hydrolite CG acts as a multifunctional moisturizer and product protection enhancer.
Hydrolite CG can also create a better sensorial experience of formulations, improve pigment dispersions, and add wetting properties.
Hydrolite CG is compatible with most anionic, non-ionic, and amphoteric cosmetic systems and most formulation types.


-Application of Hydrolite CG:
Diols contribute to high water solubility, hygroscopicity and reactivity with many organic compounds, on usually linear and aliphatic carbon chain.
Hydrolite CG, linear diol containing two primary hydroxyl groups, has bacteriostatic and bacteriacidal properties which are useful in cosmetics as a preservative.



PROPERTIES OF HYDROLITE CG:
Hydration: +15% vs untreated skin after 4hours (in vivo)
• Respects skin microbiome
• Co-wetting properties: improves the dispersion of pigments
• Product protection enhancer
• Suitable for oral care
• Colorless to white, liquid to solid, slight characteristic odor
• Water soluble
• Dosage: up to 2%
• pH of use: 3 to 12
• Up to 100°C



CLAIMS OF HYDROLITE CG:
*Moisturizing Agents
*Antimicrobials
*sensory enhancement
*protections
*moisturizing



PRODUCTION METHODS OF HYDROLITE CG:
Hydrolite CG could be obtained by epoxidation of 1-olefin with performic acid, a reaction product of hydrogen peroxide and formic acid, hydroxylation with water, or transesterification of ester produced by side reaction with methanol.



PURIFICATION METHODS OF HYDROLITE CG:
Distil the diol in vacuo and/or recrystallise it from pet ether.
The -naphthylurethane has m 112-114o.
S-(-)-Octane-1,2-diol [87720-91-0] also crystallises from pet ether with m 35-37o and D -4.7o (c 35, EtOH); R-(+)-octane-1,2-diol [87720-90-9] has similar properties but with a positive optical rotation.



PHYSICAL and CHEMICAL PROPERTIES of HYDROLITE CG:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 36.00 to 38.00 °C. @ 760.00 mm Hg
Boiling Point: 243.00 to 244.00 °C. @ 760.00 mm Hg (est)
Boiling Point: 131.00 to 133.00 °C. @ 10.00 mm Hg
Vapor Pressure: 0.006000 mmHg @ 25.00 °C. (est)
Flash Point: 228.00 °F. TCC (109.10 °C.) (est)
logP (o/w): 1.539 (est)
Soluble in:
alcohol
water, 2933 mg/L @ 25 °C (est)
Insoluble in: water
Molecular Weight: 146.23 g/mol

XLogP3: 1.8
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 6
Exact Mass: 146.130679813 g/mol
Monoisotopic Mass: 146.130679813 g/mol
Topological Polar Surface Area: 40.5 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 64.3
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular Formula / Molecular Weight: C8H18O2 = 146.23
Physical State (20 °C): Solid
Storage Temperature: Room Temperature
(Recommended in a cool and dark place, CAS RN: 1117-86-8
Reaxys Registry Number: 1719619
PubChem Substance ID: 87574263
MDL Number: MFCD00010738

CBNumber: CB8747116
Molecular Formula: C8H18O2
Molecular Weight: 146.23
MDL Number: MFCD00010738
MOL File: 1117-86-8.mol
Melting Point: 36-38 °C (lit.)
Boiling Point: 131-132 °C @ 10 mmHg (lit.)
Density: 0.914
Vapor Density: >1 (vs air)
Vapor Pressure: 0.28 Pa at 25 °C
Refractive Index: 1.4505 (estimate)
Flash Point: >230 °F

Storage Temp.: Sealed in dry, Room Temperature
Solubility: 3 g/L (20 °C)
pKa: 14.60 ± 0.10 (Predicted)
Form: Low Melting Solid
Color: Colorless to white
Water Solubility: 3 g/L (20 °C)
BRN: 1719619
LogP: 2.1 at 25 °C
CAS Database Reference: 1117-86-8 (CAS Database Reference)
EWG's Food Scores: 1
FDA UNII: 00YIU5438U
NIST Chemistry Reference: 1,2-Octanediol (1117-86-8)
EPA Substance Registry System: 1,2-Octanediol (1117-86-8)

CAS: 1117-86-8
Formula: C8H18O2
Molecular Weight: 146.23 g/mol
Quantity: 1X250MG
Storage Conditions: 20 °C
Chemical Formula: C8H18O2
Molar Mass: 146.227 g/mol
Appearance: White semi-solid
Melting Point: 30 to 35 °C (86 to 95 °F; 303 to 308 K)
Boiling Point: 140 °C (284 °F; 413 K) at 16 mmHg
CAS Number: 1117-86-8
Synonyms: octane-1,2-diol
Molecular Form: C8H18O2

Appearance: NA
Mol. Weight: 146.23
Storage: 2-8 °C Refrigerator
Chemical Name: 1,2-Octanediol / Octane-1,2-diol / Caprylyl Glycol
CAS No.: 1117-86-8
Molecular Formula: C8H18O2
Molecular Weight: 146.23
Appearance: Colorless liquid or white solid
Assay: 98% (min)
Melting Point: 36-38 °C
CAS Number: 1117-86-8
Molecular Weight: 146.227
Density: 0.9 ± 0.1 g/cm³

Boiling Point: 243.0 ± 8.0 °C @ 760 mmHg
Molecular Formula: C8H18O2
Melting Point: 36-38 °C (lit.)
Molecular Formula: C8H18O2
Molecular Weight: 146.227
Flash Point: 109.1 ± 13.0 °C
Exact Mass: 146.130676
PSA: 40.46000
LogP: 1.32
Vapor Density: >1 (vs air)
Vapor Pressure: 0.0 ± 1.1 mmHg @ 25 °C
Index of Refraction: 1.453
Water Solubility: 3 g/L (20 °C)



FIRST AID MEASURES of HYDROLITE CG:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Remove contact lenses.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROLITE CG:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROLITE CG:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROLITE CG:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROLITE CG:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROLITE CG:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available

HYDROLIZED KERATIN
Hydrolized Keratin is a large protein molecule that breaks down to penetrate the hair cuticle after a chemical treatment.
Hydrolized keratin is a fibrous structural protein found in hair, skin, nails, and other epidermal tissues in humans and animals.
Hydrolized keratin can be used as an effective ingredient to produce odor-removing and deodorizing composition.

CAS Number: 69430-36-0
Molecular Formula: C2H2BrClO2
Molecular Weight: 173.39308
EINECS Number: 274-001-1

Hydrolized keratin is a hydrolysate of keratin protein derived from acid, enzyme, and other method of hydrolysis, which has been applied in many areas including feed and food industry, pharmacy, fertilizers, pesticides, environmental protection, leather industry, and cosmetics.
Specifically, Hydrolized keratin can be mixed with polyamide 6 blend to prepare nanofibres for adsorption of chromium (Ⅵ).
Moreover, Hydrolized keratin may act as an effective component to fabricate shampoo, bath, and shower gel.

Besides, Hydrolized keratin has been demonstrated to function as an useful agent for hair fixatives.
Hydrolized Keratin results from a larger keratin molecule.
Hydrolized Keratin is broken down by cleavage of its bond with the addition of hydrogen and hydroxide (water).

Hydrolized Keratin is a cosmetic and hair care ingredient derived from natural sources, primarily animal keratin.
Hydrolized keratin is known for its role in providing strength, flexibility, and resilience to these tissues.

Hydrolized Keratin is produced naturally in the body, just like biotin.
Hydrolized Keratin, a water-soluble vitamin, aids in the metabolism of the protein that forms the basis of keratin.
Hydrolized Keratin reduces frizz, flaking and breakage.

Hydrolized Keratin increases smoothness and elasticity with its moisture binding property.
Essentially, Hydrolized Keratin helps rebuild hair's natural protective layer from the inside by increasing the diameter of each strand.
This gives a fuller appearance and replaces lost protein.

When hair treatments contain broken down or Hydrolized Keratin it creates a protective barrier in the hair and it also gives shine.
Hydrolized Keratin also works on the skin and restores moisture and improves skin elasticity.
The moisturizing properties of Hydrolized Keratin make shampoos and conditioners containing Hydrolized Keratin the preferred choice for those with brittle, dry or limp hair.

Hydrolized Keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle.
Hydrolized Keratin is most popularly derived from wool protein, silk protein, or vegan wheat protein.
Hydrolized Keratin is a skin, hair, and nail conditioning ingredient used in a variety of cosmetics.

Hydrolized Keratin is a derivative of the protein keratin created by the process of hydrolysis, where an ingredient is transformed, usually by an enzyme or acid.
Hydrolized Keratin is the primary protein in skin and hair.
Like keratin itself, Hydrolized Keratin is considered a highly biocompatible ingredient and is derived from biological waste products such as hair, wool, horns, or feathers, making it a non-vegan ingredient.

Hydrolized Keratin contains a high number of amino acids and is considered a very good ingredient for softening and strengthening hair, skin, and nails.Hydrolized Keratin can come in either liquid or powder form and has a white (in powder form) or clear color (when in liquid form).
It has been ruled safe as used in cosmetics, where its maximum rate of usage is 5% in hair styling products.
Hydrolized Keratin is a skin, hair, and nail conditioning ingredient used in a variety of cosmetics.

Hydrolized Keratin is a derivative of the protein keratin created by the process of hydrolysis, where an ingredient is transformed, usually by an enzyme or acid.
Hydrolized Keratin is the primary protein in skin and hair.
Hydrolized Keratin contains a high number of amino acids and is considered a very good ingredient for softening and strengthening hair, skin, and nails.

Hydrolized Keratin can come in either liquid or powder form and has a white (in powder form) or clear color (when in liquid form).
Hydrolized Keratin has been ruled safe as used in cosmetics, where its maximum rate of usage is 5% in hair styling products.
Hydrolized Keratin is a large protein molecule that is broken down after a chemical process in a manner such that it can penetrate the hair cuticle.

Hydrolized Keratin is sourced from a larger keratin molecule.
Hydrolized Keratin is broken down by splitting its bond with the addition of hydrogen and hydroxide (water).
At the end of the chemical process, the Hydrolized Keratin is reduced into smaller fragments that the hair can absorb, thanks to its lower molecular weight.

Hydrolized Keratin Protein is carefully monitored during its manufacture to ensure the lowest possible odor and a low ash.
It is particularly useful for treating hair that has been damaged due to permanent waving and bleaching.
Hydrolized Keratin is a highly specialized fibrous protein, derived from sheep's wool and is naturally found in hair and nails.

Adding Hydrolized Keratin Protein to formulas not only protects the hair, but also increases the amount of cystine available to the hair, minimizing damage and increasing tensile strength.
It is recommended for application in hair care products and skin treatment products.
Hydrolized Keratin is a compound that can reverse the damage done to keratin.

Hydrolized Keratin is found in many hair care products and helps rejuvenate, strengthen, and moisturize the hair.
In addition, this protein increases the smoothness of the hair.
Hydrolyzed protein can repair and condition damaged hair.

These protein hydrolysates strengthen hair fibers and reduce hair breakage.
Protein hydrolysates are often added to hair coloring products for even color absorption.
Hydrolyzed protein protects the hair from the damaging effects of permanent bleaching, waving, and straightening products.

Hydrolized Keratin improves the texture and natural structure of the hair and forms a protective coating to shield the strands.
Hydrolized Keratin, also known as Hydrolized Keratin protein, is a cosmetic and hair care ingredient derived from natural sources, primarily animal keratin.

Keratin is a fibrous structural protein found in various tissues, including hair, skin, nails, feathers, and horns.
Hydrolized Keratin plays a crucial role in providing strength, flexibility, and resilience to these tissues.

The hydrolyzed form of keratin is created through a chemical process called hydrolysis, in which the long and complex keratin protein chains are broken down into smaller, more soluble fragments.
This process makes Hydrolized Keratin suitable for use in cosmetic and hair care products.
Hydrolized Keratin is a common ingredient in hair care products, such as shampoos, conditioners, hair masks, and hair treatments.

Hydrolized Keratin is valued for its potential benefits for hair health and appearance.
Hydrolized Keratin Protein is a clear amber liquid popularly derived from wool protein.
Keratin is a structural protein that connects epithelial (skin) cells together and protects them from environmental damage.

Hydrolized Keratin is the perfect choice to tame unruly hair and make it more manageable.
Because hair is made of keratin, Hydrolized Keratin is one of the best proteins to treat heavily manipulated or damaged hair.
Usually, when the hair is exposed to chemical treatments, the amino acid cysteine breaks down, causing the hair to become weak and damaged.

Hydrolized Keratin increases cysteine content, which increases tensile strength and minimizes damage.
Hydrolized Keratin also increases volume, strengthens your hair and restores shine.
Hydrolized Keratin is a protein that makes up our hair, skin and nails.

Hydrolized Keratin is a compound that can reverse damage to keratin.
Hydrolized Keratin is found in many hair care products and helps rejuvenate, strengthen and moisturize hair.
In addition, this protein increases the smoothness of the hair.

Hydrolized Keratin is obtained from the nails, wool and horns of animals.
Hydrolized Keratin is a large protein molecule and is broken down or "hydrolyzed" into smaller molecules through enzymatic hydrolysis.
Smaller or hydrolyzed molecules have a lower molecular weight and penetrate the hair follicles, strengthening the hair structure.

Hydrolized Keratin has a similar amino acid structure to keratin naturally produced in humans.
Studies show that Hydrolized Keratin can repair and condition damaged hair.
These protein hydrolysates strengthen hair fibers and reduce hair breakage.

Protein hydrolysates are often added to hair coloring products for even color absorption.
Hydrolized Keratin protects hair from the harmful effects of permanent bleaching, waving and straightening products.
Hydrolized Keratin improves the texture and natural structure of the hair and creates a protective coating to protect the hair strands.

Hydrolized Keratin increases the moisture and elasticity of the hair and protects the hair against heat and photo-damage.
Hydrolized Keratin maintains the water content in the cortex by binding to amino acid residues produced by hair proteins.
Research shows that Hydrolized Keratin can help promote hair growth.

Hydrolized Keratin protects hair from chemical and environmental aggressors to prevent hair damage
Hydrolized Keratin also helps seal hair cuticles.
This minimizes frizz and prevents flyaway.

Amino acids from Hydrolized Keratin neutralize the negative electrical charge in the hair, eliminating frizz and friction.
Hydrolized Keratin is a protein originally derived from wool.
Hydrolized Keratin is most often used in hair care and skin care products.

The hydrolysis process allows the keratin particles to be more easily absorbed by the skin or hair, making it an ideal ingredient for deep conditioning treatments.
This form of keratin provides essential proteins for restoring and maintaining healthy skin and hair.
Hydrolized Keratin has an amino acid structure similar to natural human hair.

Hydrolized Keratin is known to increase the tensile strength of damaged hair.
Hydrolized Keratin is essentially a large protein molecule that has undergone a chemical process and is broken down to penetrate the hair cuticle.
Hydrolized Keratin is most commonly derived from wool protein, silk protein or vegan wheat protein.

Hydrolized Keratin is an ingredient used to improve hair strength, elasticity and shine.
Hydrolized Keratin can help boost naturally occurring keratin levels in hair follicles, helping to protect hair from damage from outside sources such as heat styling or exposure to harsh chemicals.
Hydrolized Keratin can help nourish and protect the hair follicle while improving texture as it seals in moisture in the hair.

Boiling Point: 215.0 °C
Melting Point: 31.5 °C
Flash Point: 230 °F
Density: 1.9848 g/cu cm
LogP3-AA: 1.3
Exact Mass: 171.89267
Monoisotopic Mass: 171.89267
Topological Polar Surface Area: 37.3 Ų
Physical Description: Crystalline compound
Vapor Pressure: 1.4X10-1 mm Hg
Chemical Classes: Other Classes -> Organic Acids
Odor: Characteristic
EWG's Food Scores: 1-2

Hydrolized Keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle.
Hydrolized Keratin moisturizes and conditions both skin and hair and also forms a film when used on the skin or nails.
Hydrolized Keratin is put through a hydrolysate process which makes the keratin stronger.

Hydrolized Keratin also does not penetrate the hair shaft.
It acts as a film-forming ingredient, creating a protective coating on the hair.
This also helps to increase the shininess of the hair.

Hydrolized Keratin Protein is a highly specialized fibrous protein found in hair, feathers, wool and nails.
Hydrolized Keratin increases hair's moisture content, restores shine and fullness, and improves manageability.
Hydrolized Keratin differs from other proteins in that it is rich in cysteine (a sulfur-containing amino acid), which gives keratin its unique strength and protective quality.

Hydrolized Keratin is very useful in any hair and skin care formulation, as it is the essential component of skin and hair.
The Hydrolized Keratin protein, which is an important protein of the hair, can be easily absorbed by the hair thanks to the hydrolysis (hydrolysis) process.
Hydrolized Keratin can both protect and repair hair condition.

Hydrolized Keratin is used on hair that has been damaged by chemicals or heat, such as dye or perm, to help hair return to the strong, moist and shiny it was before.
Hydrolized Keratin is used on permed hair to help your hair look more beautiful.
This is because the polypeptide strands are absorbed by the hair, making the hair peptide bind more tightly.

Hydrolized Keratin preserves and strengthens the health and youthfulness of hair and nails: hair becomes shinier, less brittle, hair loss slows down, nails become more flexible.
Hydrolized Keratin strengthens, softens and makes the skin more supple by protecting it from free radicals.
Hydrolized Keratin is used in nail care products.

Hydrolized Keratin can help strengthen the hair shaft, improving its resistance to breakage and damage.
Hydrolized Keratin has the ability to attract and retain moisture, which can help keep the hair hydrated and reduce frizz.
Hydrolized Keratin can contribute to smoother hair cuticles, which can result in shinier and more manageable hair.

Hydrolized Keratin may assist in repairing damaged hair, particularly hair that has been exposed to heat styling, chemical treatments, or environmental stressors.
Some products containing Hydrolized Keratin claim to enhance hair volume and thickness.
Hydrolized Keratin can help reduce frizz and improve the overall texture of the hair.

Hydrolized Keratin, which is also used in anti-aging care products
Hydrolized Keratin undergoes a hydrosolate treatment that makes the keratin stronger.
Hydrolized Keratin also does not penetrate the hair shaft.

Hydrolized Keratin acts as a film-forming ingredient that creates a protective coating on the hair.
This also helps to increase the shine of the hair.
Hydrolized Keratin provides moisturizing benefits for both hair and skin.

Hydrolized Keratin is used in shampoo, conditioner, care (hair), rinse, styling, body wash, body lotion, care (body), cleanser, toner, facial moisturizer, care (face), make-up foundation, mascara, lipstick, coloring. cosmetics.
Fine, porous, damaged and chemically treated hair will get the most benefit from Hydrolized Keratin.
Hydrolyzed Wheat Protein reduces the porosity of the hair and strengthens it from the inside, making your hair healthier, shinier and easier to style.

Hydrolized Keratin increases your hair's ability to absorb and retain moisture.
Hydrolized Keratin helps reduce breakage, eliminates frizz and tangles, and makes your hair look fuller.
Hydrolized Keratin Protein is a highly specialized fibrous protein found in hair, feather, wool and nails.

Hydrolized Keratin increases the moisture content of the hair restoring luster, body and increasing manageability.
Hydrolized Keratin is distinct from other proteins in that it is rich in cysteine (a sulfur-containing amino acid) giving keratin a unique strength and protective quality.
Chemical processes such as coloring, straightening, and relaxation, as well as exposure to heat and UV rays, can damage hair and leave it weak and lackluster.

Hydrolized Keratin is compatible with a wide range of other cosmetic ingredients commonly found in hair care formulations.
Hydrolized Keratin can be incorporated into shampoos, conditioners, serums, masks, and styling products to provide various benefits to the hair.
Hydrolized Keratin can be derived from various sources, including animal keratin (such as feathers, hooves, and horns), human hair, and plant-based sources.

The source of the Hydrolized Keratin can affect the properties and labeling of the product.
Hydrolized Keratin may specify the source on their labels.
Hydrolized Keratin is available in different forms, including liquid solutions, powders, and serums.

The choice of form depends on the product's intended use and formulation requirements.
Hydrolized Keratin is suitable for various hair types, from straight to curly, and can benefit both natural and chemically-treated hair.
It is often used in products designed for damaged or frizzy hair.

Some hair care products containing Hydrolized Keratin claim to provide heat protection when using hot styling tools like hair straighteners or curling irons.
This can help reduce heat-related damage to the hair.
With regular use, Hydrolized Keratin-containing products may contribute to the long-term improvement of hair health and appearance.

However, individual results can vary, and it's important to maintain a consistent hair care routine.
Hydrolized Keratin can help extend the longevity of hair color treatments by sealing the hair cuticle and preventing color fading caused by washing and environmental factors.

Hydrolized Keratin is often used in products designed to improve the texture and manageability of the hair, making it easier to style and reducing tangles.
Hydrolized Keratin is considered a protein-based ingredient, and it is sometimes included in products marketed as "protein treatments" or "reparative treatments" for damaged hair.

Uses
Hydrolized Keratin should be mixed with your moisturizing conditioner and used as a deep conditioner or protein treatment, depending on the porosity level of your hair.
Hydrolized Keratin is a multifunctional cosmetic ingredient used in personal care products to strengthen, repair and maintain hair health.
Hydrolized Keratin keeps hair strands moist for longer.

Amino acid-cysteine is broken down in damaged hair, which causes the hair to become damaged and brittle.
Hydrolized Keratin repairs damaged strands by increasing the cysteine content in the hair shaft.
Hydrolized Keratin softens dry and frizzy hair, making it more manageable.

Hydrolized Keratin creates a thin protective film on the hair, adding shine to the hair strands.
Hydrolized Keratin softens hair and increases its elasticity, preventing breakage and split ends.
Hydrolized Keratin is an important ingredient used in a variety of hair and skin care items, ranging from shampoos and conditioners to sunscreen lotions.

Hydrolized Keratin is used in shampoo, conditioner, treatment (hair), leave-in, styling, body wash, body lotion, treatment (body), cleanser, toner, facial moisturizer, treatment (face), makeup foundation, mascara, lipstick, color cosmetics.
Hydrolized Keratin is often included in shampoos to help strengthen hair, improve its resilience, and reduce breakage.
Hydrolized Keratin may also contribute to smoother and more manageable hair.

In conditioners, Hydrolized Keratin can provide moisturizing benefits, reduce frizz, and enhance the shine of the hair.
Hydrolized Keratin may help repair damaged hair and improve its overall texture.
Hydrolized Keratin is a common ingredient in hair masks and treatment products designed to provide deep conditioning and repair for damaged or stressed hair.

Hydrolized Keratints often target issues like split ends and breakage.
Some styling products, such as serums and leave-in conditioners, contain Hydrolized Keratin to provide additional protection against heat damage from styling tools and to improve the manageability of the hair.
Hydrolized Keratin can help maintain and protect hair color by sealing the hair cuticle and reducing color fading caused by washing and exposure to UV radiation.

Hair serums containing Hydrolized Keratin are used to reduce frizz, enhance shine, and provide a smooth and polished finish to the hair.
Hydrolized Keratin is often included in products marketed as protein treatments or reparative treatments for damaged hair.
These treatments aim to strengthen and revitalize weakened or chemically-treated hair.

Some hair growth products may include Hydrolized Keratin as an ingredient to promote healthier hair growth and reduce hair loss.
Hydrolized Keratin treatments, commonly known as "keratin hair treatments" or "Brazilian blowouts," are offered as salon services.
These treatments are designed to reduce frizz, improve hair texture, and provide long-lasting smoothness to the hair.

Besides hair care products, Hydrolized Keratin may also be found in certain skincare products, such as creams and lotions, where it is used to improve skin texture and hydration.
Hydrolized Keratin can be included in hair volumizing products to provide a fuller and thicker appearance to fine or thinning hair.
Some intensive hair repair and reconstruction treatments contain high concentrations of Hydrolized Keratin to address severe damage and restore the hair's health.

Hydrolized Keratin is used in products designed for curly and textured hair to help define curls, reduce frizz, and enhance the natural pattern of the hair.
Heat protectant sprays and hair serums may contain Hydrolized Keratin to shield the hair from damage caused by heat styling tools like hair dryers and flat irons.
Hydrolized Keratin can be included in daily hair care products as a preventative measure to maintain the overall health and strength of the hair, even before signs of damage become noticeable.

Leave-in conditioners often contain Hydrolized Keratin to provide continuous moisture and protection throughout the day, making hair more manageable and reducing tangles.
Hydrolized Keratin can be found in both conventional and natural or organic hair care products, catering to consumers with various preferences.
Some hair primers or styling primers include Hydrolized Keratin to create a smooth base for styling and to enhance the longevity of the desired hairstyle.

Hydrolized Keratin is integrated into daily hair care regimens to help maintain the health and appearance of the hair, addressing issues like dryness, brittleness, and dullness.
Hydrolized Keratin is a key ingredient in products specifically marketed for strengthening and fortifying hair, particularly for individuals with weak or fragile hair.

Hydrolized Keratin is commonly found in products aimed at reducing frizz and promoting smoother, sleeker hair.
Some hair oil treatments incorporate Hydrolized Keratin to nourish and protect the hair while providing a luxurious feel and shine.

Safety Profile
While allergic reactions to Hydrolized Keratin are rare, they can occur in individuals who are sensitive or allergic to certain protein-based ingredients.
Hydrolized Keratin's advisable to perform a patch test before using a product containing Hydrolized Keratin, especially if you have a history of skin allergies.

Products containing Hydrolized Keratin, like other cosmetic products, may cause eye and skin irritation if they come into direct contact with these areas.
In case of contact, rinse with plenty of water and seek medical attention if irritation persists.

Although the risk is low, inhaling aerosolized particles or vapors from certain hair care products containing Hydrolized Keratin may cause minor respiratory irritation in some individuals.
Besides Hydrolized Keratin, cosmetic and hair care products may contain other ingredients that individuals could be sensitive or allergic to.
Always check product labels for a full list of ingredients and discontinue use if you experience any adverse reactions.

Synonyms
Hydrolyzed animal keratin
69430-36-0
Hydrolized Keratin
Keratin, hydrolyzed
Keratins, hydrolyzates
Cattle hair
EINECS 274-001-1
Keratin hydrolyzate
Keratins, cattle horn, saponified and neutralized
HYDROLIZED RICE PROTEIN
Hydrolized rice protein extracted from sustainable, non-GMO rice bran, is a water soluble, cosmetic grade vegetable protein that is rich in amino acids beneficial to hair and skin.
Hydrolized rice protein, known for being a mild material, is often used by allergy-prone or sensitive individuals.
Hydrolized rice protein appears as a fine powder that is typically white or off-white in color.

CAS Number: 156715-40-1

Hydrolized rice protein is one of mankind's most ancient and valued sources of nutrients.
Hydrolized rice protein is naturally gluten-free.
Hydrolyzed rice protein is a derivative of rice protein that has undergone a process called hydrolysis.

During hydrolysis, larger protein molecules are broken down into smaller peptides or amino acids by the action of enzymes or acid.
This process results in a protein that is easier for the body to absorb and use.
Hydrolyzed Rice Protein has been shown to significantly increase total hair volume by up to 32%.

Hydrolized rice protein also adds natural shine and highlights to the hair.
By increasing the ability of the hair and skin to bind moisture, it leads to increased flexibility and tensile strength.
On the skin, the increased moisture retention creates a more hydrated and elastic surface.

Hydrolyzed Rice Protein is an effective anti-irritant and leaves a smooth, dry feel on the skin.
Hydrolyzed Rice Protein is a protein-rich cosmetic ingredient that offers a range of different benefits for hair and skin.

Hydrolyzed Rice Protein has excellent moisturizing properties, helps to improve hair strength and elasticity, and promotes skin hydration.
Hydrolized rice protein is also responsible for evening out the skin tone and reducing the early signs of aging like fine lines and wrinkles.
This protein is often added to products like shampoos, conditioners, serums, and lotions.

Hydrolyzed rice protein (also known as rice protein hydrolysate) is typically categorized as a skin/hair conditioning agent, but research shows its benefits extend beyond that thanks to its antioxidant and peptide content.
Furthermore, studies indicate this ingredient has potential for evening skin tone and helps to inhibit certain processes in skin that cause dehydration.
Hydrolyzed Rice Protein’s also worth noting that hydrolyzed rice protein is rich in amino acids.

Technically speaking, hydrolyzed rice protein is derived from rice grains that have undergone hydrolysis (chemically reacted) with an acid, enzyme or other methods.
This ingredient can be “upcycled” as a byproduct of the rice production process.
Hydrolyzed rice protein was reaffirmed as a safe cosmetic ingredient in the 2006 Cosmetic Ingredient Review report.

The notated concentrations levels of hydrolyzed rice protein at that time were between 0.1–2.0% but more recent usage levels suggested by cosmetic suppliers may be higher (up to 5% based on what we found).
Hydrolyzed Rice Protein is an amber, low-viscous liquid with characteristic inherent odour.
Hydrolyzed Rice Protein is suitable as a care additive for application in the personal care products such as after-sun, body-, color- & face care, conditioning, liquid soaps, shampoos, hair coloring and styling products.

Hydrolyzed Rice Protein also used in baby care & cleansing, face cleansing, personal care wipes and shower/bath formulations.
Hydrolyzed rice protein contains proteins with both cationic (positive) and anionic (negative) charges.
This opposing charges help add volume to hair by repelling one another.

Hydrolyzed Rice Protein has a thin and watery texture and has a pH somewhere in between 4.0 and 6.0.
Hydrolyzed Rice Protein is used in many skincare formulations due to its many benefits. One of the most essential benefits of hydrolysed rice protein is that it increases the skin’s ability to absorb and retain moisture.
Hydrolyzed Rice Protein also benefits the hair by increasing its elasticity and tensile strength.

Hydrolyzed Rice Protein is derived from rice where rice protein is subjected to hydrolysis.
This involves breaking down the protein molecules into smaller peptides and amino acids.
This process can be achieved by using enzymes or acids, resulting in Hydrolyzed Rice Protein.

Hydrolyzed Rice Protein is an excellent addition to any skincare and hair care product, including shampoo and conditioner bars.
Hydrolyzed Rice Protein is made of natural rice bran fiber, which means it is gluten free and vegan.
Hydrolyzed Rice Protein is a superb vegetable protein that delivers high amounts of amino acids to both hair and skin.

Using hydrolyzed rice protein in hair care products can help increase total hair volume and help to strengthen strands.
The key aminos are arginine, histidine, and lysine. These all contribute to stronger, healthier hair.
Hydrolyzed Rice Protein does not have to be in wash-off formulas so consider using it in your leave-in hair care formulas.

Leave in conditioners, styling sprays, serums, scalp treatments and more! We have a huge compliment of excellent hair treatment ingredients.
When using it in skincare products, Hydrolyzed Rice Protein delivers high levels of moisture and the amino acids help to boost natural collagen production and build up skin density.

Hydrolyzed rice protein is a versatile alternative to cosmetic grade proteins, which is carefully processed to yield a low odor and color product, which is freely soluble in water.
This provides all the benefits of the more traditional animal-derived proteins but does not carry any negative connotation of said products.
Hydrolyzed rice protein is obtained from non-GMO rice, which is a hypo-allergenic protein source.

Hydrolyzed Rice Protein forms a moisture-retentive film on the skin and hair.
These films have a variety of beneficial uses in cosmetic applications.
Hydrolyzed Rice Protein works by depositing large amounts of cationic amnio acids.

These bond to the hair strands, smoothing the rough edges, then the anionic amino acids cause a repelling action to the naturally negatively charged hair fibers, giving hair more volume.
The more the hair is washed/conditioned with products using just 1% Hydrolyzed Rice Protein, the more volume shown without it just being fizzy.
Hydrolyzed Rice Protein does not create “dry” strands, which then appear to be volume but are really just dry.

Hydrolyzed Rice Protein smooths the hair follicles and creates volume.
Studies show anywhere from 13% to 32% increase with regular use.
Hydrolysed rice protein has calming and soothing properties due to its ingredients.

Hydrolyzed Rice Protein helps in reducing the itchiness of the skin.
Hydrolyzed Rice Protein peptides promote protection against the harmful UV rays of the sun.
They end up protecting the thin layer of skin from sun damage and photoaging.

Hydrolysed rice protein stimulates the synthesis of collagen in fibroblast cells of the skin.
Collagen is a protein that keeps the skin firm, plump and gives it its elasticity.
Thus, the application of rice protein on the skin leads to boosting collagen, thereby tightening the skin and keeping wrinkles and fine lines at bay.

Hydrolyzed Rice Protein has been shown to significantly increase total hair volume by up to 32%.
Hydrolyzed Rice Protein also adds natural shine and highlights to the hair.
By increasing the ability of the hair and skin to bind moisture, it leads to increased flexibility and tensile strength.

On the skin, the increased moisture retention creates a more hydrated and elastic surface.
Hydrolyzed Rice Protein is an effective anti-irritant and leaves a smooth, dry feel on the skin.
Hydrolyzed Rice Protein contains both cationic and anionic amino acids.

Hydrolyzed Rice Protein is derived from rice, a common cereal grain.
The hydrolysis process breaks down the complex protein structure into smaller components, making it more soluble and potentially easier for the body to digest.
Hydrolyzed rice protein is often used in cosmetic and personal care products.

Due to its smaller molecular size, Hydrolyzed Rice Protein can be incorporated into lotions, shampoos, and other formulations to provide benefits such as improved moisture retention and conditioning for the hair and skin.
Hydrolyzed Rice Protein may be used as a protein supplement in the diet.
The hydrolysis process can enhance its digestibility and absorption.

Rice protein, including hydrolyzed rice protein, is considered hypoallergenic and is an alternative for individuals who are allergic to common protein sources like soy or dairy.
Hydrolyzed Rice Protein is naturally gluten-free, making hydrolyzed rice protein a suitable option for individuals with gluten sensitivities or celiac disease.
As a plant-derived protein, hydrolyzed rice protein is suitable for vegan and vegetarian diets.

pH: 4.0-6.0
Solubility: Soluble in water
Viscosity: Low

Hydrolyzed Rice Protein is a water soluble, cosmetic grade vegetable protein that is rich in amino acids beneficial to hair and skin.
Hydrolyzed Rice Protein can be used in shampoos, conditioners, hair treatments, hand and nail creams, body lotions, facial cleansers and moisturisers of all types.
Hydrolyzed Rice Protein is rich in cationic amino acids which are substantive to hair and skin (such as Arginine, Histidine, and Lysine ) and anionic amino acids that repel hair fibers for greater volume (such as Aspartic Acid and Glutamic Acid).

Hydrolyzed Rice Protein extract is excellent for helping the skin bind with moisture.
This results in skin developing great flexibility and elasticity.
Since it helps in retaining moisture, skin becomes hydrated and its tensile strength also increases.

When the skin develops abnormal coloration in the form of dark patches or spots due to many factors including UV exposure and acne, the condition is called hyperpigmentation.
The spots get their colour from a pigment called melanin which is in turn released by the abnormal secretion of enzyme tyrosinase.
Hydrolyzed Rice Protein peptides actively help in countering hyperpigmentation by controlling the release of this enzyme, thereby mitigating excess melanin production and deposition in the skin.

Being an anti-irritant, hydrolysed rice protein is excellent for people with skin conditions wherein their skin feels dry, itchy, flaky or scaly skin.
This is due to its ability to retain moisture in the skin.
Hydrolyzed Rice Protein peptides are helpful in increasing the synthesis of ceramides.

These are small lipids that give the skin a barrier to aid in retaining moisture that can be lost due to harsh environmental elements, for instance, harmful UV radiations.
Thus, hydrolysed rice protein ends up not just hydrating the skin, but protecting it as well.
Hydrolyzed Rice Protein, which is produced by secretion of enzyme tyrosinase, is a pigment responsible for skin colouration.

Since hydrolysed rice protein helps in controlling melanin production by decreasing tyrosinase production, the skin becomes lighter and the texture improves.
After a few applications, can get a calmer and even-toned skin.
Hydrolysed rice protein can help in boosting this process, thereby exfoliating the skin.

This results in skin looking smoother and helps in controlling acne as well.
When applied topically, Vitamin E has been found to provide hydration to the skin.
Hydrolyzed Rice Protein is fat-soluble property makes it restore the moisture and keep dryness at bay.

Hydrolyzed Rice Protein has antioxidants and anti-inflammatory properties that are capable of treating dry skin conditions such as psoriasis and dermatitis.
Hydrolyzed Rice Protein boosts the blood supply to the epidermis.
This leads to nourishment reaching the skin and in turn making it healthy and supple.

Hydrolyzed Rice Protein is beneficial in combating melanin deposition in the skin.
This leads to even toned and lighter skin texture.
Hydrolyzed Rice Protein help boost blood supply to the skin.

This property helps in slowing down the process of ageing.
Hydrolyzed Rice Protein is especially helpful in treating wrinkles around the eyes.
Due to its antioxidant and moisturising properties, Hydrolyzed Rice Protein acts as an excellent ingredient for diminishing the appearance of dark circles.

Hydrolyzed Rice Protein acts as an excellent cleanser by unclogging the pores.
Hydrolyzed rice protein enhances the manageability and body of hair.
Hydrolyzed Rice Protein smoothes hair cuticles and improves gloss and texture by providing a protective film on damaged hair.

Hydrolyzed Rice Protein also increases hair moisture content resulting in greater flexibility and tensile strength.
Hydrolyzed Rice Protein is ability to increase the moisture capacity in hair results in a healthier and fuller appearance.
Hydrolyzed rice protein is low molecular weight with 1500-2000 dalton, thereby having the ability to penetrate the hair and may treat hair loss and damage.

Hydrolyzed rice protein is also great for skin, with anti-aging, and moisturization benefits.
Hydrolyzed Rice Protein is an excellent anti-irritant that leaves the skin feeling smooth and dry due to its hydration and skin elasticity benefits.
Hydrolyzed rice protein forms a non-tacky film that helps to minimize roughness and wrinkles.

Hydrolyzed Rice Protein has a protective colloid effect which results in better skin resistance to pollutants and external irritants.
Due to its moisturizing and film-forming properties, a moisture-retentive barrier is formed which helps to plump up the skin and combat detergency aggressiveness.
In cosmetics and hair care products, hydrolyzed rice protein is often included for its potential benefits to the hair.

Hydrolyzed Rice Protein can help improve the texture of hair, enhance manageability, and provide a conditioning effect.
The small molecular size allows Hydrolyzed Rice Protein to penetrate the hair shaft, offering moisturizing and strengthening properties.
Hydrolyzed rice protein has film-forming properties, which means it can create a thin film on the surface of the skin or hair.

This film can help retain moisture, improve texture, and contribute to a smoother appearance.
When included in skincare formulations, hydrolyzed rice protein can contribute to skin hydration.
The smaller peptides may help improve the absorption of moisture, providing a hydrating effect.

Some research suggests that hydrolyzed rice protein may possess antioxidant properties.
Antioxidants help neutralize free radicals, which can contribute to skin aging and damage.
Hydrolyzed rice protein is sometimes marketed as a collagen-boosting ingredient.

While it doesn't contain collagen itself, the amino acids and peptides derived from hydrolyzed rice protein may support collagen production in the skin.
Hydrolyzed rice protein is often considered a natural ingredient.

Hydrolyzed Rice Protein is derived from a plant source and is free from some of the common allergens found in other protein sources.
Due to its water-soluble nature, hydrolyzed rice protein can be easily incorporated into a variety of formulations, including lotions, creams, serums, shampoos, and conditioners.

Uses:
Hydrolyzed Rice Protein is a scientific/chemical process by which a substance is broken down typically using an acid or water.
Hydrolyzed Rice Protein of a protein (like wheat, oat, silk, rice, etc..) has special applications in personal care products since it allows the product, with the hydrolysate added, to absorb more quickly in to hair or skin.
Hydrolyzed Rice Protein contains certain amino acids from whichever protein used and those will be absorbed more rapidly than the intact proteins by the outermost keratin (protein) layer of skin or hair, thus maximizing nutrient delivery to the intended place.

Hydrolyzed rice protein can be incorporated into grooming products for pets, providing similar benefits to those in human hair care products, such as improved texture and conditioning.
Hydrolyzed Rice Protein and its derivatives may find applications in tissue engineering, where it can contribute to the development of biomaterials with specific properties.
The film-forming properties of hydrolyzed rice protein may be utilized in the development of wound dressings to promote healing and provide a protective barrier.

Hydrolyzed Rice Protein might be used in the formulation of organic fertilizers or soil amendments to enhance plant growth and nutrient uptake.
The film-forming characteristics of hydrolyzed rice protein can be employed in the paper industry for coatings that improve paper quality and printability.
Hydrolyzed Rice Protein can be explored as a component in the development of biodegradable adhesives with potential applications in various industries.

Some derivatives of hydrolyzed rice protein may have applications in water treatment processes, assisting in the removal of certain pollutants.
Hydrolyzed Rice Protein could be considered as a bio-based material for the development of sustainable polymers and plastics.
Hydrolyzed Rice Protein may contain bioactive peptides that could have health-promoting effects, and these peptides may be explored for various health and nutritional applications.

Hydrolyzed rice protein, with its neutral taste, might be used as a flavor enhancer in savory food products.
Hydrolyzed rice protein may be incorporated into protein bars, shakes, or other sports nutrition products to provide a plant-based protein source for individuals with dietary restrictions or preferences.
Given that rice protein is naturally gluten-free, hydrolyzed rice protein can be used in the formulation of gluten-free products, providing a protein source for individuals with gluten sensitivities or celiac disease.

Hydrolyzed rice protein may be used in the formulation of functional beverages, such as protein-fortified drinks or smoothies.
Hydrolyzed rice protein might find application in the production of baby formulas or infant nutrition products.
In the food industry, hydrolyzed rice protein might be used to improve the texture, mouthfeel, or structure of processed foods.

In the pharmaceutical industry, hydrolyzed rice protein may be explored for drug delivery systems, especially in cases where controlled release or improved solubility is desired.
Hydrolyzed rice protein can be used in the textile industry, contributing to processes such as fabric conditioning and finishing.
Hydrolyzed rice protein may be included in nutraceutical formulations, combining nutritional and pharmaceutical properties in products that offer health benefits.

Hydrolyzed rice protein, being plant-derived, is often used in formulations that aim to be environmentally friendly and sustainable.
Hydrolyzed Rice Protein is the chemical process that is used to break down protein into amino acids for easy absorption.
This process is applied to rice bran protein to make it water-soluble, and it is then called hydrolysed rice protein or rice peptides.

These peptides are in fact small proteins that benefit the skin in a number of ways.
Hydrolyzed rice protein is often included in shampoos, conditioners, and hair treatments.
Hydrolyzed Rice Protein can help improve the texture and manageability of hair, providing a conditioning effect.

In skincare formulations such as lotions, creams, and serums, hydrolyzed rice protein can contribute to skin hydration and may have antioxidant properties.
Hydrolyzed Rice Protein is sometimes included in anti-aging products for its potential collagen-boosting effects.
Hydrolyzed rice protein, in its powdered form, may be used as a protein supplement in dietary products such as protein powders or nutritional shakes.

The hydrolysis process can enhance its digestibility.
While less common than other protein sources, hydrolyzed rice protein can be used in food products.
Hydrolyzed Rice Protein may be added to enhance the protein content of certain foods, especially in products catering to individuals with allergies to common protein sources like soy or dairy.

Hydrolyzed rice protein might be used in the formulation of medical foods or nutritional products, particularly in cases where individuals have specific dietary requirements or restrictions.
Hydrolyzed rice protein can also find applications in pet food, contributing to the protein content of pet nutrition products.

The film-forming properties of hydrolyzed rice protein make it suitable for use in industrial applications, such as coatings or films for certain materials.
Given its plant-based origin, hydrolyzed rice protein is often used in the formulation of vegan and vegetarian food products.

Safety Profile:
Hydrolyzed Rice Protein is a safe ingredient that is well tolerated by most skin and hair types.
Hydrolyzed Rice Protein does not have any known side effects, but patch testing must be done when using the ingredient for the first time.
Hydrolyzed Rice Protein is also generally vegan and halal.

Synonyms:
PROTEIN HYDROLYZATES, RICE
156715-40-1
DTXSID901042242
HYDROLYZED BEESWAX
HYDROLYZED CASEIN, N° CAS : 65072-00-6, Nom INCI : HYDROLYZED CASEIN, N° EINECS/ELINCS : 265-363-1, Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien de la peau : Maintient la peau en bon état
HYDROLYZED CASEIN
HYDROLYZED CELLULOSE, Nom INCI : HYDROLYZED CELLULOSE, Ses fonctions (INCI) : Déodorant : Réduit ou masque les odeurs corporelles désagréables. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent bouclant ou lissant (coiffant) : Modifie la structure chimique des cheveux, pour les coiffer dans le style requis
HYDROLYZED CELLULOSE
Hydrolyzed Collagen; collagen hydrolysate; collagen peptide; gelatine; gelatine hydrolysate and hydrolyzed gelatine. cas no: 92113-31-0
HYDROLYZED COLLAGEN
HYDROLYZED GELATIN, N° CAS : 68410-45-7, Nom INCI : HYDROLYZED GELATIN, N° EINECS/ELINCS : 270-082-2, Ses fonctions (INCI): Agent d'entretien de la peau : Maintient la peau en bon état
HYDROLYZED ELASTIN
Hydrolyzed elastin is mainly composed of the so-called β-elastin, the low molecular weight elastin peptide.
Hydrolyzed Elastin is an active ingredient obtained by enzymatic degradation of fiber protein elastin.


CAS Number: 91080-18-1
EC Number: 293-509-4
Chem/IUPAC Name: Elastins, hydrolyzates


Hydrolyzed Elastin is usually sourced from the skin of fish, which is why it can also be referred to as “marine elastin.”
The Cosmetic Ingredient Review Expert Panel reviewed hydrolyzed elastin and deemed it safe for use in cosmetics.
Typical usage levels for hydrolyzed elastin range from 1–5%.


Hydrolyzed Elastin is an active ingredient obtained by enzymatic degradation of fiber protein elastin.
Usually, the source of elastin is bovine.
This multifunctional ingredient is a non-viscous, amber-colored, clear to the slightly opalescent solution, which is clearly fluorescent under UV light.


Hydrolyzed elastin is mainly composed of the so-called β-elastin, the low molecular weight elastin peptide.
Besides, Hydrolyzed Elastin contains small quantities of elastin peptides of a higher molecular weight and some naturally occurring collagen hydrolysates.
Hydrolyzed Elastin (a.k.a. Marine Collagen) offers numerous benefits when it comes to skin care.


Not only does Hydrolyzed Elastin function as a humectant, but it can also promote cell growth and help maintain skin elasticity.
Elastin is naturally present in skin—the second most common protein in the human body, in fact—and it’s what gives skin its springy, elastic texture.
Hydrolyzed Elastin, also known as Marine Collagen, is a natural protein harvested from fish and other sources that can be used to replenish your skin.


Hydrolyzed elastin is elastin that’s been broken down into amino acids through the process of hydrolysis.
Elastin’s naturally occurring in the body, working hand-in-hand with collagen to promote a firm, tight appearance.
Elastin’s true talent comes in the form of physical resiliency, allowing skin to “bounce back” like elastic after stretching.


Although hydrolyzed elastin is derived from elastin protein, it cannot function like elastin does within the body, as its molecules are far too large to penetrate beyond skin’s surface when applied topically.
Unlike collagen, Hydrolyzed Elastin’s much harder to stimulate the regeneration of elastin within the extracellular matrix (area of skin between the epidermis and dermis).


That’s why it’s important to maintain the health of the elastin already present in skin through the consistent usage of sun safe practices, such as the application of a broad-spectrum SPF 30+ sunscreen every day.
Hydrolyzed Elastin is a hydrolyzed elastin protein obtained from fish skin and carefully monitored during its manufacture to ensure the lowest possible odor and a low ash.


Hydrolyzed Elastin is a highly specialized elastic protein which is found in the connective tissue of the skin and blood vessels.
Hydrolyzed Elastin contains 10-15% of protein.
Specific gravity of Hydrolyzed Elastin is 1.04.


Hydrolyzed Elastin is Gluten-free.
Hydrolyzed Elastin revitalizes, nourishes and moisturizes the skin and improves the appearance of wrinkles and fine lines.
Hydrolyzed Elastin works best in firming/lifting and tightening applications.


Hydrolyzed Elastin powder is extracted from pork tendons by biotechnology and is amphipathic, i.e. hydrophilic and lipophilic, which makes it compatible with most of the ingredients.
Hydrolyzed Elastin is a fiber protein made up of polypeptide subunits and one of the most important structural proteins in the human body.


Hydrolyzed Elastin is a fermented, hydrolyzed elastin from the connective tissue of bonito fish.
As the name implies, Elastin is a highly elastic protein in the connective tissue that allows the skin to return to its original position when stretched.
Collagen is the main component of skin; elastin holds the collagen bundles together and gives skin its elasticity.


Aging causes elastin production to slow down, therefore skin loses elasticity, and wrinkles begin to form.
Hydrolyzed Elastin helps restore the elasticity of skin.
Hydrolyzed Elastin has been shown to provide additional benefits, including improvements in vascular elasticity and blood flow.


Hydrolyzed Elastin supports joint mobility, healthy ligaments, and a healthy, non-sagging bust.
Hydrolyzed Elastin can also be considered for a surgical recovery product.
Hydrolyzed elastin is protein obtained from fish skin.


Hydrolyzed Elastin is a highly specialized elastic protein which is found in the connective tissue of the skin that gradually lessens as we age.
Further, Hydrolyzed Elastin is a humectant that helps trap moisture, holding it against the skin.
Hydrolyzed Elastin belongs to the following substance groups Haircare substances / Conditioning agents, Ingredients for skincare.


A hydrolysate of natural elastin, Hydrolyzed Elastin works synergetically with hydrolyzed collagen, and has been documented to prevent and counteract premature loss of elasticity to restore a young and smooth appearance to the skin.
Hydrolyzed Elastin is an essential component of the skin.


Hydrolyzed Elastin is similar to collagen, but can be stretched (elastic) more, thus making our skin flexible.
Hydrolyzed Elastin is also an important structure that keeps skin cells properly aligned.
So that Hydrolyzed Elastin can be absorbed into the skin more easily.


Hydrolyzed Elastin is white powder-light color.
Hydrolyzed Elastin can dissolve in water.
Hydrolyzed Elastin is a naturally derived, water-soluble protein of bovine origin.


Hydrolyzed Elastin is one of the three main proteins found in the skin, along with collagen and reticulin.
Specific gravity of Hydrolyzed Elastin is 1.04.
Hydrolyzed Elastin is clear to slightly hazy yellow to medium amber liquid.


Hydrolyzed Elastin is slight characteristic odor.
Hydrolyzed Elastin is soluble in water.
Hydrolyzed Elastin is preserved with butylene glycol, phenoxyethanol, and ethylhexlglycerin.



USES and APPLICATIONS of HYDROLYZED ELASTIN:
The activity of elastin hydrolysates ( α-, β-, κ-elastin) after the local external application has not yet been clarified completely and exhaustively.
Studies showed that elastin fragments activate skin fibroblast and boos extracellular matrix components production, including collagen and elastin.
Also, Hydrolyzed Elastin's a perfect source of building blocks for producing those essential proteins.


However, Hydrolyzed elastin may be regarded as a protective protein with affinity to skin and hair.
Hydrolyzed Elastin is used as an additive to skincare cosmetics such as nourishing creams and body lotions; it is also very suitable for hair treatment products.


In skin care, Hydrolyzed Elastin’s humectant properties are used to help hydrate skin through the attraction of moisture to skin’s surface.
Hydrolyzed Elastin provides a layer of protection to the hair and improves e.g. skin elasticity by preventing dry skin and reducing wrinkles.
Hydrolyzed Elastin is suitable for various applications such as in skin creams, firming creams, sunscreens, masks, hair products.


Hydrolyzed Elastin, which helps maintain skin elasticity.
Hydrolyzed Elastin strengthens the tone of the skin, strengthens it and therefore prevents the formation of wrinkles.
Hydrolyzed Elastin is a protein which along with hyaluronic acid and collagen, are the main components of the connective tissue of the skin.


Hydrolyzed Elastin offers protection, keeping the cells hydrated while improving the elasticity of the skin.
Hydrolyzed Elastin's use is recommended for facial cream products for normal and mature skin and for hair care products.
Hydrolyzed Elastincan be easily incorporated into cosmetic formulas during the cooling process.


Hydrolyzed Elastin is used in almost all anti-aging, repair and rejuvenating care products.
Use of Hydrolyzed Elastin for making cosmetics: Recommended use dosage 5-10%.
Hydrolyzed Elastin is also an important load-bearing tissue and used in places where mechanical energy is required to be stored.


Hydrolyzed Elastin gives skin and hair a protective layer. Rebuilds elastic strength to hair and reduces breakage.
Hydrolyzed Elastin effectively reduces hair damage from harsh chemicals.
Hydrolyzed Elastin is used for all Anti-aging products.


Hydrolyzed Elastin is used Dietary Supplement, and Cosmetics & Cosmeceuticals.
Applied topically, Hydrolyzed Elastin helps attract and retain moisture.
Hydrolyzed elastin protein obtained from fish skin and carefully monitored during its manufacture to ensure the lowest possible odor and a low ash.


Hydrolyzed Elastin is a highly specialized elastic protein which is found in the connective tissue of the skin and blood vessels.
Hydrolyzed Elastin is also an important load-bearing tissue and used in places where mechanical energy is required to be stored. pH value: 4.5-5.5.
Hydrolyzed Elastin can be used added to formulas as is; add to water-phase of formula.


Recommended use level of Hydrolyzed Elastin: 1-5%. Store in refrigerator.
Hydrolyzed Elastin is used Anti-aging and anti-wrinkle skin care products; hair care products including shampoos, hair conditioners, hair balms, and hair pomades.


-Cosmetic Uses of Hydrolyzed Elastin:
*antistatic agents
*film formers
*hair conditioning
*humectants
*skin conditioning



HYDROLYZED ELASTIN BENEFITS:
- Hydrolyzed Elastin serves to give flexibility to the skin.
- Skin looks moist



FUNCTIONS OF HYDROLYZED ELASTIN IN COSMETIC PRODUCTS:
*HAIR CONDITIONING:
Hydrolyzed Elastin leaves the hair easy to comb, supple, soft and shiny and / or imparts volume

*SKIN CONDITIONING:
Hydrolyzed Elastin maintains the skin in good condition

*SKIN CONDITIONING - EMOLLIENT:
Hydrolyzed Elastin softens and smoothens the skin



PROPERTIES OF HYDROLYZED ELASTIN:
~ Anti-wrinkle.
~ Firming the body.
~ Against stretch marks.



COSMETIC BENEFITS OF HYDROLYZED ELASTIN:
*low molecular weight Elastin with >= 80 %, that is extracted from pork *tendon by biotechnological methods
*amphipathic, i.e., hydrophilic & lipophilic
*shows a build-up effect on the hair
*acts as a natural conditioning agent and strengthens the hair
*shows a significant delay of swelling degree on hair during alkaline *process (perms and dying)
*reduces breakage of hair
*improves skin elasticity
*helps to prevent dry skin
*reduces wrinkles and delays aging



FUNCTIONS OF HYDROLYZED ELASTIN:
*Emollient:
Hydrolyzed Elastin softens and softens the skin
*Hair conditioner:
Hydrolyzed Elastin leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine
*Skin conditioning agent:
Hydrolyzed Elastin keeps the skin in good condition



WHAT DOES HYDROLYZED ELASTIN DO IN A FORMULATION?
*Antistatic
*Film forming
*Hair conditioning
*Humectant
*Skin conditioning



FORMULATIONS WITH HYDROLYZED ELASTIN:
*Hair care:
Clear Conditioning and Strengthening Rinse
*Hair care:
2-Layer Hair Tonic "Shake before use"



HYDROLYZED ELASTIN AT A GLANCE:
*Elastin that’s been separated into amino acids through hydrolysis
*Serves as a humectant, attracting water to skin
*Promotes a soft, hydrated appearance
*Safe for use in cosmetics



FUNCTION OF HYDROLYZED ELASTIN:
Hydrolyzed elastin protein is an active aqueous solution of marine derived elastin from fish skin. It is an excellent moisturizer and film former.
Hydrolyzed Elastin provides an easy way to add marine elastin to skin care emulsions, toners and surfactant systems for body and hair care.
"Hydrolyzed" means: hydrolysed or a hydrolysate (product of the separation of a chemical compound by reaction with water, often by means of enzymes).



FEATURES AND BENEFITS OF HYDROLYZED ELASTIN:
Hydrolyzed Elastin is a hydrolyzed form of elastin, this allows the product to be more bioavailable and digestible.
Hydrolyzed Elastin is a one-of-a-kind product to create a Beauty from Within cosmetic product.
Hydrolyzed Elastin contains Desmosine and Isodesmosine. These are cross-linking molecules that are only found in elastin and give elastin its unique properties.



BENEFITS OF HYDROLYZED ELASTIN:
Hydrolyzed Elastin is a humectant. Humectants are valuable in any skin care routine because they trap moisture, holding it against the skin.
Elastin, in particular, is a skin conditioner that will help your skin maintain its elasticity as you age.
This protein also has use as a skin booster.
When applied topically, Hydrolyzed Elastin stimulates cell growth so, when used over time, elastin’s renewing effect makes your skin look smoother and fresher.



DERMATOLOGICAL TIPS, HYDROLYZED ELASTIN:
While Hydrolyzed Elastin can be used in the morning or evening, we recommend that you make sure this ingredient is a part of your evening routine.
That way your skin reaps the benefits as you sleep.



PHYSICAL and CHEMICAL PROPERTIES of HYDROLYZED ELASTIN:
INCI: Hydrolyzed Elastin
Appearance, odour: light yellow powder
Solubility: water soluble
Use concentration: 0.5 - 5.0 %



FIRST AID MEASURES of HYDROLYZED ELASTIN:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROLYZED ELASTIN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROLYZED ELASTIN:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROLYZED ELASTIN:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROLYZED ELASTIN:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of HYDROLYZED ELASTIN:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Hydrolyzed Elastin 25%
Unilastin 25
Hydrolyzed animal elastinHydrolyzed elastin
Elastin Hydrolysate
Unilastin


HYDROLYZED GELATIN
HYDROLYZED GUAR, N° CAS : 9000-30-0, Origine(s) : Végétale, Nom INCI : HYDROLYZED GUAR, N° EINECS/ELINCS : 232-536-8, Additif alimentaire : E412, Ses fonctions (INCI) : Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
HYDROLYZED GUAR
KERATIN (5% IN WATER); Keratins, hydrolyzates;HYDROLYZED KERATIN;Proteinhydrolysat;Cattle hair;Keratin hydrolyzate;Keratins,cattle horn,saponified and neutralized;HYDROLYSED KERATINE CAS:69430-36-0
HYDROLYZED KERATIN
HYDROLYZED MILK PROTEIN; Hydrolyzed proteinCAS Number‎: ‎92797-39-2
HYDROLYZED KERATIN
Hydrolyzed keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle.
Hydrolyzed keratin moisturizes and conditions both skin and hair and also forms a film when used on the skin or nails.
Hydrolyzed keratin is used in creams, lotions, moisturizers, nail creams as well as shampoos, leave on cream, conditioners, serums.

CAS: 69430-36-0
MF: C2H2BrClO2
MW: 173.39308
EINECS: 274-001-1

Hydrolyzed keratin is a hydrolysate of keratin protein derived from acid, enzyme, and other method of hydrolysis, which has been applied in many areas including feed and food industry, pharmacy, fertilizers, pesticides, environmental protection, leather industry, and cosmetics.
Specifically, this substance can be mixed with polyamide 6 blend to prepare nanofibres for adsorption of chromium (Ⅵ).
Moreover, Hydrolyzed keratin may act as an effective component to fabricate shampoo, bath, and shower gel.
In addition, Hydrolyzed keratin can be used as an effective ingredient to produce odor-removing and deodorizing composition.
Besides, Hydrolyzed keratin has been demonstrated to function as an useful agent for hair fixatives.

Hydrolyzed keratin is a compound that can reverse the damage done to keratin.
Hydrolyzed keratin is found in many hair care products and helps rejuvenate, strengthen, and moisturize the hair.
In addition, Hydrolyzed keratin increases the smoothness of the hair.
Hydrolyzed keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle.
Hydrolyzed keratin is most popularly derived from wool protein, silk protein, or vegan wheat protein.

Hydrolyzed keratin is a skin, hair, and nail conditioning ingredient used in a variety of cosmetics.
Hydrolyzed keratin is a derivative of the protein keratin created by the process of hydrolysis, where an ingredient is transformed, usually by an enzyme or acid.
Hydrolyzed keratin is the primary protein in skin and hair.
Like keratin itself, hydrolyzed keratin is considered a highly biocompatible ingredient and is derived from biological waste products such as hair, wool, horns, or feathers, making it a non-vegan ingredient.
Hydrolyzed keratin contains a high number of amino acids and is considered a very good ingredient for softening and strengthening hair, skin, and nails.
Hydrolyzed keratin can come in either liquid or powder form and has a white (in powder form) or clear color (when in liquid form).
Hydrolyzed keratin has been ruled safe as used in cosmetics, where its maximum rate of usage is 5% in hair styling products.

Bromochloroacetic acid is a monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is replaced by bromine while a second is replaced by chlorine.
A low-melting (27.5-31.5℃), hygroscopic crystalline solid, Hydrolyzed keratin can be formed during the disinfection (by chlorination) of water that contains bromide ions and organic matter, so can occur in drinking water as a byproduct of the disinfection process.
Hydrolyzed keratin is a monocarboxylic acid, an organochlorine compound and a 2-bromocarboxylic acid.

Hydrolyzed Keratin Protein is a clear amber liquid popularly derived from wool protein. Hydrolyzed keratin is a structural protein that connects epithelial (skin) cells together and protects them from environmental damage.
Hydrolyzed keratin is a form of protein that has been broken down into smaller parts such that it can penetrate hair cuticles.
Hydrolyzed keratin strengthens the hair, reduce frizz and increase hair elasticity and shine.
Hydrolyzed keratin is also good for the skin, keeping it firm and less prone to sagging.

Hydrolyzed keratin Chemical Properties
Odor: Characteristic
EPA Substance Registry System: Hydrolyzed keratin (69430-36-0)
Boiling Point: 214.8°C at 760 mmHg
Melting Point: 31.5°C
pH: 5.5-7.5
Solubility: Soluble in water

Hydrolyzed keratin is a large protein molecule that is broken down after a chemical process in a manner such that it can penetrate the hair cuticle.
Hydrolyzed keratin is sourced from a larger keratin molecule.
Hydrolyzed keratin is broken down by splitting its bond with the addition of hydrogen and hydroxide (water).
At the end of the chemical process, Hydrolyzed keratin is reduced into smaller fragments that the hair can absorb, thanks to its lower molecular weight.

Uses
Hydrolyzed keratin is a processed form of keratin that facilitates its use in skin care formulations.

Benefits
Hydrolyzed protein can repair and condition damaged hair.
These protein hydrolysates strengthen hair fibers and reduce hair breakage.
Protein hydrolysates are often added to hair coloring products for even color absorption.
Hydrolyzed protein protects the hair from the damaging effects of permanent bleaching, waving, and straightening products.
Hydrolyzed keratin improves the texture and natural structure of the hair and forms a protective coating to shield the strands.

Toxicology
Hydrolyzed keratin sourced from sheep wool and hoof meal was non-toxic in oral studies in rats (i.e. the LD50 was greater than 40 ml/kg in a 20% solution).
Keratin (MW = 8000 Da and 33,000 Da; buffalo horn/hoof source) and Hydrolyzed Keratin (MW = 310 Da; sheep wool source) were non-toxic in intravenous studies in mice.

Synonyms
Bromochloroacetic acid
5589-96-8
2-bromo-2-chloroacetic acid
Acetic acid, bromochloro-
Keratins
Chlorobromoacetic acid
68238-35-7
69430-36-0
Keratin from Wool,
bromo(chloro)acetic acid
UNII-AL8MZ37Y51
2-Bromo-2-chloroethanoic acid
AL8MZ37Y51
CCRIS 8228
DTXSID4024642
CHEBI:64206
HSDB 7619
KERATIN
C2H2BrClO2
BROMOCHLOROACETICACID
Cheratina
Detoxin
Animal keratin
acetic acid, 2-bromo-2-chloro-
bromochloracetic acid
Cheratina [Italian]
BCAA
BrCH(Cl)COOH
bromochloroethanoic acid
BrCH(Cl)CO2H
2-bromo-2-chloroaceticacid
C2-H2-Br-Cl-O2
Bromochloroacetic acid, 97%
SCHEMBL135012
CHEMBL504842
DTXCID604642
GEHJBWKLJVFKPS-UHFFFAOYSA-N
EINECS 269-409-1
Tox21_200894
BROMOCHLOROACETIC ACID [IARC]
CHLOROBROMOACETIC ACID [HSDB]
LMFA01090146
MFCD00143872
AKOS016010266
CS-O-30541
LS-1370
NCGC00091488-01
NCGC00091488-02
NCGC00258448-01
BS-52910
Bromochloroacetic acid, analytical standard
CAS-5589-96-8
FT-0623228
FT-0627572
FT-0627573
C19212
E78199
Q27133122
Bromochloroacetic acid 1000 microg/mL in Methyl-tert-butyl ether
HYDROLYZED KERATIN
HYDROLYZED KERATIN = KERATIDE = PROMOIS WK-F


CAS Number: 69430-36-0
EC Number: 274-001-1
MDL Number: MFCD00131434
Molecular Formula: C2H2BrClO2


Hydrolyzed keratin is a large protein molecule that is broken down after a chemical process in a manner such that it can penetrate the hair cuticle.
Hydrolyzed Keratin is sourced from a larger keratin molecule.
Essentially, hydrolyze means to fragment the protein or break into smaller pieces in a non-specific manner.
The broken-down proteins deposit themselves on the hair’s shaft.


Firstly, keratin is a protein that’s naturally found in your hair.
Hydrolyzed keratin is responsible for your hair’s health.
While keratin makes your hair strong, it’s also prone to damage due to environmental aggressors.
For this reason, hydrolyzed keratin has been introduced into several hair care formulations to supplement what has been weakened.


Hydrolyzed keratin is a large protein molecule that is broken down after a chemical process in a manner such that it can penetrate the hair cuticle.
Hydrolyzed keratin is sourced from a larger keratin molecule.
Keratin is broken down by splitting its bond with the addition of hydrogen and hydroxide (water).
At the end of the chemical process, the keratin is reduced into smaller fragments that the hair can absorb, thanks to its lower molecular weight.


Essentially, hydrolyze means to fragment the protein or break into smaller pieces in a non-specific manner.
The broken-down proteins deposit themselves on the hair’s shaft.
Due to the low molecular weight and the small size, the hydrolyzed keratin proteins go beyond the cuticle, penetrate the hair shaft and reduce damage.


Don’t confuse hydrolyzed keratin with Brazilian keratin treatments.
Hydrolyzed keratin doesn’t possess any straightening properties.
Keratin is a protein that makes up our hair, skin, and nails.
Unfortunately, constant exposure to heat styling equipment and harsh chemicals can damage it.


Hydrolyzed keratin is a compound that can reverse the damage done to keratin.
Hydrolyzed keratin is found in many hair care products and helps rejuvenate, strengthen, and moisturize the hair.
Hydrolyzed keratin increases the smoothness of the hair.
Hydrolyzed keratin is extracted from the nails, wools, and horns of animals.


Hydrolyzed keratin is a large protein molecule and is broken down or “hydrolyzed” into smaller molecules through enzymatic hydrolysis.
The smaller or hydrolyzed molecules have lower molecular weight and penetrate the hair shafts and strengthen the hair structure.
Hydrolyzed keratin has a similar amino acid structure as the keratin produced naturally in humans.
Hydrolyzed keratin is one of the components whose importance has increased as nutritional supplements, which are one of the alternative methods in hair care, are gradually starting to take their place in our lives.


Keratin protein, which has a large molecular weight, whose name we have started to hear frequently in hair and nail health, has passed through different processes and has become a part of our care routine with its various forms.
One of these processes is carried out by breaking down the keratin protein, that is, by hydrolyzing it.
Thus, Hydrolyzed keratin is better absorbed by the body with its small molecular weight.


Keratin is a structural protein that makes up hair and nails.
We owe the shine and durability of our hair and the strength of our nails to the naturally occurring keratin protein in their structure.
Of course, this protein is not capable of maintaining its effectiveness and quantity under all conditions.
As we age and are exposed to harmful factors, the production of keratin in our hair and nails decreases.


Therefore, as a part of our care routine, we need to include products containing keratin into our lives.
At this point, it is necessary to distinguish the most effective methods of keratin care, in which way and in which form the keratin will be used.
Although some recommended methods and procedures for keratin care create positive changes in the appearance of your hair in the short term, they may be damaging the hair cells due to the chemicals applied.


Apart from that, keratin is a large molecule in its natural state.
In other words, as long as it has not undergone any enzymatic treatment, it has such dimensions that hair and nail cells cannot benefit because of its low bioavailability.
In order to achieve the most efficient effects from keratin, it must have a small molecular weight and be easily absorbed by our cells.


This is where the important function of hydrolyzed keratin comes into play.
Hydrolyzed keratin is created by breaking down the keratin protein by adding hydrogen and hydroxide (water).
Hydrolyzed keratin, which has a lower molecular weight, is absorbed much more quickly and easily by the hair cell and begins to show its numerous benefits in a short time.


Despite the fact that the keratin care applied in beauty salons contains processes that wear out the hair, using hydrolyzed keratin as a food supplement has both healthier and more effective benefits.
A large protein molecule that penetrates the hair shaft to strengthen hair, reduce frizz, and increase elasticity, this multifunctional ingredient can temporarily turn back the clock on damage and fortify hair.


Hydrolyzed keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle.
Hydrolyzed keratin is most popularly derived from wool protein, silk protein, or vegan wheat protein.
Hydrolyzed keratin is essentially a large protein molecule that has gone through a chemical process that is broken down in a way that allows it to penetrate the hair cuticle.


Hydrolyzed keratin moisturizes and conditions both skin and hair and also forms a film when used on the skin or nails.
Hydrolyzed keratin is derived from wool and is a light yellow to amber transparent liquid with a special odor.
Hydrolyzed keratin must be treated with a special biological treatment, into a short peptide, can be bioavailable.
The treated keratin is a potential source of high quality protein with high nutritional value and stable quality.


Hydrolyzed Keratin is water soluble.
Easy to add Hydrolyzed Keratin to existing or your own custom formulas.
Pure hydrolyzed keratin will make a difference in your hair the first time you use Hydrolyzed Keratin.
Hydrolyzed Keratin will only get better every time after that!


Each strand of hair will become thicker, stronger and more resilient, making the appearance of your hair overall thicker and fuller, shiny & fabulous!
Keratin that has been hydrolyzed is stronger than regular keratin.
Hydrolyzed Keratin penetrates and coats hair resulting in smooth appearance.


You can add 1-2 ml straight, directly to your dry hair about 10-15 minutes before shampooing and conditioning.
Hydrolyzed Keratin is put through a hydrosolate process which makes the keratin stronger.
Hydrolyzed Keratin also does not penetrate the hair shaft.
Sheep-wool-derived, hydrolyzed keratin protein is carefully monitored during its manufacture to ensure the lowest possible odor and low ash.


Hydrolyzed keratin is a highly specialized fibrous protein found in hair, feathers, wool, and nails.
Hydrolyzed keratin is distinct from other proteins in that it is rich in cysteine (a sulfur-containing amino acid) giving keratin a unique strength and protective quality.
Sheep-wool derived, hydrolyzed alpha-keratin protein carefully monitored during its manufacture to ensure the lowest possible odor and a low ash.


Hydrolyzed keratin is a highly specialized fibrous protein, which is found in hair, feathers, wool and nails. Keratin is distinct from other proteins in that it is rich in cysteine (a sulfur-containing amino acid) giving keratin a unique strength and protective quality.
Derived from sheep's wool.


Hydrolyzed keratin appears as a light yellow powder.
Hydrolyzed keratin , Hydrolyzed is a sheep-wool derived, hydrolyzed alpha-keratin protein carefully monitored during its manufacture to ensure the lowest possible odor and a low ash.
Keratin is a highly specialized fibrous protein, which is found in hair, feathers, wool and nails.


Hydrolyzed keratin is distinct from other proteins in that it is rich in cysteine (a sulfur-containing amino acid) giving keratin a unique strength and protective quality.
Derived from sheep's wool.
Contains 20-23% of protein.


Developed using the most recent advances in proteomics, the amino acid sequences of the peptides found in this product match those present in the keratin proteins found in cuticular and cortical regions of human hair.
Hydrolyzed keratin is a protein that makes up your hair, skin and nails – as much as 85% of it.
Hydrolyzed keratin is stronger than steel and its resilient nature is what helps hair to hold up against daily wear and tear.


However, regular heat styling, colouring and exposure to harsh environmental conditions damages the structure of the keratin proteins, which gradually makes the hair weaker and more prone to split ends.
Hydrolyzed keratin can be added to products to help reinforce the strands – but the size of the molecules are often too large to penetrate through the hair cuticles so the protein simply sits on the top of hair and doesn’t actually improve the condition.


Hydrolyzed keratin goes through a process called ‘enzymatic hydrolysis’, breaking down the large keratin molecules into smaller ones.
Hydrolyzed keratin is done by splitting the bond with hydrogen and water so the molecules are able to penetrate the hair shaft and strengthen it from the inside.
Hydrolyzed keratin works by filling any microscopic gaps within the cuticle and medulla, which gradually increases the diameter of individual strands.


This leaves them feeling smoother, softer and thicker while also making them more resistant to further damage.
Hydrolyzed keratin is a product derived from the enzymatic hydrolysis of wool keratin resulting in an aqueous solution.
Thanks to its composition of amino acids, hydrolyzed keratin is very similar to the keratin of human hair, while due to its balanced molecular weight it creates a protective film on the hair.


Hydrolyzed keratin is therefore an excellent addition to shampoos, conditioners, masks or lotions for hair damaged by dyes or other technical treatments, dull and dry hair and brittle nails!
Hydrolyzed keratin is one of the main substances that make up the hair structure.
However, over time, due to chemical effects, the use of tools such as a dryer and flat iron and even washing, parts of this component are lost.


The problem is even greater in frizzy hair which, due to its shape, has irregular deposits.
One of the solutions is to replace this material with hydrolyzed keratin.
This product is a hydrolyzed keratin of low molecular weight.
Hydrolyzed keratin is one of the structural proteins composing the stratum corneum, hair, and nails.


Hydrolyzed keratin comprises 80% of human hair.
In terms of its amino acid composition, Hydrolyzed keratin has cystine, which is rarely seen in any other kinds of protein.
In association with disulfide bond, Hydrolyzed keratin has a very unique molecular structure, so the peptide is well cross-linked.
Because of this structure, many functional end groups such as amino groups and carboxyl groups exist within a single molecule.


Consequently, high adsorption can be achieved with keratin.
Hydrolyzed keratin is a compound that can reverse the damage done to keratin.
Hydrolyzed keratin is found in many hair care products and helps rejuvenate, strengthen, and moisturize the hair.
In addition, Hydrolyzed keratin increases the smoothness of the hair.


Hydrolyzed keratin can repair and condition damaged hair.
Hydrolyzed keratin strengthen hair fibers and reduce hair breakage.
Hydrolyzed keratin are often added to hair coloring products for even color absorption.
Hydrolyzed keratin protects the hair from the damaging effects of permanent bleaching, waving, and straightening products.


Hydrolyzed keratin improves the texture and natural structure of the hair and forms a protective coating to shield the strands.
Hydrolyzed Keratin Protein is a clear amber liquid popularly derived from wool protein.
Keratin is a structural protein that connects epithelial (skin) cells together and protects them from environmental damage.
Hydrolyzed keratin is a form of protein that has been broken down into smaller parts such that it can penetrate hair cuticles.


Hydrolyzed keratin strengthens the hair, reduce frizz and increase hair elasticity and shine.
Hydrolyzed keratin is also good for the skin, keeping it firm and less prone to sagging.
Hydrolyzed keratin is water soluble, add to water phase
Hydrolyzed keratin is heat stable, Store in refrigerator.


Hydrolyzed Keratin Protein Keratin which is an important protein of hair Through the process of hydrolysis (hydrolysis) so that it can be easily absorbed into the hair.
Hydrolyzed keratin can both protect and restore hair condition.
Hydrolyzed keratin is suitable for damaged hair from dyeing, perming or bleaching.


Mixing method: Can be mixed in water (water phase) directly.
Product characteristics: White-light powder
Solubility: can dissolve in water
Keratin is a protein which is naturally found on the hair shaft.


It is a prerequisite for maintaining healthy hair.
Hydrolyzed keratin is hydrolyzed .i.e broken down into smaller fragments by treating it with water, acid and the hydrolyzed keratin thus formed is of relatively smaller size and has a lower molecular weight which can be easily absorbed into the hair shaft.
Hydrolyzed keratin deposits easily on the hair shaft and repairs the damaged strands, thus providing strength to your strands.


Hydrolyzed Keratin Protein is well known and one of the most reviewed ingredients.
Hydrolyzed Keratin is put through a hydrosolate process which makes the keratin stronger.
Hydrolyzed Keratinalso does not penetrate the hair shaft.
Hydrolyzed keratin acts as a film forming ingredient which creates a protective coating on the hair.


Hydrolyzed keratin is a highly specialized fibrous protein, which is found in hair, feathers, wool and nails.
Hydrolyzed keratin is distinct from other proteins in that it is rich in cysteine (a sulfur-containing amino acid) giving keratin a unique strength and protective quality
Hydrolyzed Keratin Protein is a clear amber liquid popularly derived from wool protein.


Hydrolyzed Keratin is known to increase cysteine available to the hair, thus, diminishing and curing the hair of damage.
Hydrolyzed keratin is also known to increase the tensile strength of the hair.
Hydrolyzed Keratin increases hair cell elasticity and volume.
Hydrolyzed keratin is also known to have very high moisture binding capabilities thereby aiding hair strenght and fluidity, this in turn increases hair luster, body, and increasing manageability.


Hydrolyzed Keratin is a fibrous protein of the epidermis and its adnexa such as hair and nails.
Hydrolyzed keratin enhances and strengthens the structure of damaged hair and nails, restoring their polish and healthy look; besides Hydrolyzed keratin maintains a proper level of moisturizing.
Hydrolyzed keratin is a powerful hair rebuilder that strengthens the hair by replenishing the Keratin that the hair loses over time with chemical and physical processes, thus improving the structure of the fiber, leaving hair healthier and completely renewed.


Hydrolyzed keratin recomposes the capillary mass, controlling elasticity.
Hydrolyzed keratin provides anti-drying action leaving hair resistant to breakage, soft, malleable and shiny.
Hydrolyzed Keratin can make your hair soft and frizz-free by keeping it hydrated and well-conditioned.
Hydrolyzed keratin forms a protective layer by filling the gaps, replacing the lost protein, and enhancing the overall diameter of the hair, thus improving its density.


Many haircare brands are incorporating Hydrolyzed Keratin in the product formulation to supplement the loss of Keratin.
Keratin is a large protein molecule that cannot penetrate the hair shaft easily and need to be broken down into smaller fragments so that they can penetrate the hair shaft.
Hydrolyzed Keratin is a smaller protein easily absorbed into the hair's cuticle.


Hydrolyzed keratin comes from a larger keratin molecule.
Keratin is broken down into smaller fragments by enzymatic hydrolysis to allow easier penetration into the hair shaft.
The hydrolyzed Keratin is smaller and has a relatively low molecular weight due to its low molecular weight.
Hydrolyzed keratin penetrates the hair shaft and repairs the damaged strands, adding strength, elasticity, and shine to your hair.


Sheep-wool derived, hydrolyzed alpha-keratin protein carefully monitored during its manufacture to ensure the lowest possible odor and a low ash.
Hydrolyzed keratin is a highly specialized fibrous protein, which is found in hair, feathers, wool and nails.
Hydrolyzed keratin is distinct from other proteins in that it is rich in cysteine (a sulfur-containing amino acid) giving keratin a unique strength and protective quality.


Hydrolyzed keratin is derived from sheep's wool.
Hydrolyzed Keratin is a product that contributes to hair health from the inside out.
The keratin derives from bird feathers. Hair is approximately 80-95% keratin.
Psychologically, hair is an important aspect of body image for men and women.


We regularly change this image, for example by adapting our hair to a specific occasion or to the latest fashion.
Cosmetic changes to our hair, such as coloring and curling, are accompanied by chemical processes that change the normal structure of the hair shaft.
Extra support with hydrolysed keratin can help out.
Hydrolyzed Keratin is probably not vegan.


Hydrolyzed keratin is a chemically altered Keratin, used in cosmetics.
Keratin is a protein usually derived from ground-up hooves, horns, feathers, quills, and hair of various captive and killed animals.
However, just in the last few years some vegan plant-derived keratins have become available.
Hydrolyzed Keratin Cas No: 69430-36-0 is made from waterfowl feather, which is consisted of Keratin like human hair.


Hydrolyzed keratin is Amino Acid composition very similar to human hair.
Besides, the structure of the Keratin from feather is different with Wool’s keratin.
The feather keratin molecules have many β-sheet structures, so we call β-keratin.


Because of its planar structure, it has a very flexible molecular structure.
By biological enzyme hydrolysis processing, we cut the high molecular weight Keratin to keratin peptide with small molecular weight, which is water-soluble and better compatibility with cosmetics formulations.


Type of ingredient: Strengthener
Main benefits of Hydrolyzed keratin: Reduces breakage, minimizes damage, and increases elasticity and shine
Who should use Hydrolyzed keratin: Curly, kinky, and dry/damaged hair
How often can you use Hydrolyzed keratin: Every six to eight weeks
Works well with: Your average shampoo and conditioner



USES and APPLICATIONS of HYDROLYZED KERATIN:
Due to the low molecular weight and the small size, the hydrolyzed keratin proteins go beyond the cuticle, penetrate the hair shaft and reduce damage.
Hydrolyzed keratin is used to build up bonds rather than break them.
You can find many hair care products like shampoos, conditioners, hair masks, and serums containing Hydrolyzed keratin.


Hydrolyzed keratin acts as a moisturizer that traps moisture in the hair layers.
In cosmetics, Hydrolyzed keratin is used to smooth and moisturize the damaged hair cuticle.
Hydrolyzed keratin fills cracks and eliminates frizz associated with dryness.
UHydrolyzed keratin is used as Antistatic, Film forming, Hair conditioning, Humectant, Skin conditioning.


Hydrolyzed keratin is used in creams, lotions, moisturizers, nail creams as well as shampoos, leave on cream, conditioners, serums.
Hydrolyzed keratin is used to smooth and moisturize the damaged hair cuticle.
Hydrolyzed keratin fills cracks and eliminates frizz associated with dryness.
Hydrolyzed keratin helps fill the minor gaps throughout the hair shaft, including its three layers known as the cuticle, cortex, and medulla.


Filling these microscopic gaps with broken-down protein helps to strengthen hair's structure, thereby improving its overall elasticity.
Hydrolyzed keratin minimizes the damaging effects of sun exposure, heat styling, chemical treatments, and combing hair - tangled tresses.
Hydrolyzed keratin is used as an antistatic agent that reduces static electricity by neutralizing the electrical charge on the surface of hair.
Hydrolyzed keratin conditions the hair and leaves them easy to comb, soft and shiny and/or gives volume, lightness and shine


Hydrolyzed keratin provides moisturizing benefits for both hair and skin.
Hydrolyzed Keratin can be used in hair treatment, shampoo, conditioner, styling, leave-in, bodywash, body lotion, body treatments, cleanser, toner, facial moisturizer, face, treatment, mascara, lipstick, color cosmetics, makeup foundation.
Revitalizes the hairs natural protective layer and rebuilds tensile strength.


Hydrolyzed keratin returns elasticity and reduces breakage.
Hydrolyzed keratin reduces hair damage from harsh chemicals.
Hydrolyzed keratin acts also as a protective care substance on the skin.
Hydrolyzed keratin is used for Complete range of hair care, Strengthening care, Nail care, Anti-ageing care.


Hydrolyzed keratin is preserved with butylene glycol, phenoxyethanol, and ethylhexlglycerin.
Hydrolyzed Keratin provides moisturizing benefits for both hair and skin.
Hydrolyzed keratin is used in shampoo, conditioner, treatment (hair), leave-in, styling, body wash, body lotion, treatment (body), cleanser, toner, facial moisturizer, treatment (face), makeup foundation, mascara, lipstick, color cosmetics.


Hydrolyzed keratin acts as a film-forming ingredient, creating a protective coating on the hair.
Hydrolyzed keratin also helps to increase the shininess of the hair.
Revitalizes the hairs natural protective layer and rebuilds tensile strength
Returns elasticity and reduces breakage


Hydrolyzed keratin reduces hair damage from harsh chemicals
Hydrolyzed keratin acts also as a protective care substance on the skin
Hydrolyzed keratin can be added to formulas as is; add to water-phase of formula.
Recommended use level: 0.2-3%.


All kinds of hair care products including shampoos, hair conditioners, hair balms, hair pomades and also skin care products including lotions and creams.
Thanks to high bio-availability, Hydrolyzed keratin strengthens hair, nails and skin, and prevents their ageing.
Youth strengthener for hair, nails and skin


Hydrolyzed keratin is the key structural material making up the outer layer of human skin.
Hydrolyzed keratin is also the key structural component of hair and nails.
Offers detangling and also provides targeted repair to the most damaged areas of the hair's surface.
Hydrolyzed keratin finds use in hair care.


Hydrolyzed keratin acts as a conditioning agent.
Hydrolyzed keratin is used for chemically treated hair.
Conditions hair, strengthens the strand and improves its elasticity, contributing to make it resistant to breakage.
This daily-use formula leaves hair more manageable and easier to style, because it keeps it sealed from roots to ends.


Contributes to improve the health of the hair follicles, promoting the growth of stronger and healthier strands.
Liquid organic fertilizer based on concentrated keratin hydrolysate in NPK 9-2-3 formulation with amino acids, specially designed for stages of vegetative growth.
With free amino acids that provide resistance to water stress factors, inclement weather, pests and diseases and a great implicit bio stimulant effect.


Hydrolyzed keratin is used for damaged hair.
Hydrolyzed keratin is an ideal option for daily use, repairing the hair structure and strengthening it.
Contains hydrolyzed keratin that contributes to improve the health of the strand, to maintain the cuticle sealed and to improve the hair’s sheen.
Perfect complement to prolong and give maintenance to straightening procedures, especially those keratin-based.


Hydrolyzed keratin reduces hair damage from harsh chemicals
Acts also as a protective care substance on the skin
Hydrolyzed keratin can be added to formulas as is; add to water-phase of formula.
Recommended use level: 1-5%. Store in refrigerator.


Applications include All kinds of hair care products including shampoos, hair conditioners, hair balms, hair pomades and also skin care products including lotions and creams.
Hydrolyzed keratin recovers hair elasticity, restoring lost keratin to the hair.
Rebuilding hair strands, Hair Brasil Liquid Keratin restores the vitality, elasticity and shine of your hair.


Hydrolyzed keratin reinforcing and repairing existing damage.
Functions are actives-hydrolized protein.
Applications are Hair Conditioner, MaskBaby Product, Hair Fixative Shampoo, Shower Gel, Body Wash.
Hydrolyzed keratin is a hydrolysate of keratin protein derived from acid, enzyme, and other method of hydrolysis, which has been applied in many areas including feed and food industry, pharmacy, fertilizers, pesticides, environmental protection, leather industry, and cosmetics.


Specifically, Hydrolyzed keratin can be mixed with polyamide 6 blend to prepare nanofibres for adsorption of chromium (Ⅵ).
Moreover, Hydrolyzed keratin may act as an effective component to fabricate shampoo, bath, and shower gel.
In addition, Hydrolyzed keratin can be used as an effective ingredient to produce odor-removing and deodorizing composition.
Besides, Hydrolyzed keratin has been demonstrated to function as an useful agent for hair fixatives.


Hydrolyzed keratin is a processed form of keratin that facilitates its use in skin care formulations.
Hydrolyzed keratin reduces hair breakage and damage.
Hydrolyzed keratin act as a natural protective layer and improve tensile strength
Hydrolyzed keratin reduces hair damage from harsh chemicals and sun


Hydrolyzed keratin acts also as a protects and hydrates skin and hair
Coats damaged hair with protein preventing split end
Strengthens and smooths hair
Hydrolyzed keratin reduces frizz and static electricity caused by dryness


Hydrolyzed keratin boosts volume and body, allows hair to hold styles much better
Hydrolyzed keratin is very effective in hair care, forming a protective barrier to prevent moisture loss and damage
Hydrolyzed keratin strengthens hair, increasing elasticity and reduces breakage
Hair feels silky, soft and more manageable


Hydrolyzed keratin is used Conditions and moisturises skin
Hydrolyzed keratin is used for dry, damaged, or processed hair
Hydrolyzed keratin is used in Hair care products, Shampoos, Conditioners, Creams & Lotions
Hydrolyzed keratin is suitable for all skin types


Hydrolyzed keratin is used on damaged hair from being damaged by chemicals or heat, such as through dyeing or perming, to help restore hair To come back strong, moisturized and shiny as before.
Hydrolyzed keratin is used on permed hair to help make your hair look more beautiful.
This is because the polypeptide strands are absorbed into the hair and make the hair peptide binding more tightly.


Hydrolyzed keratin is used For hair restoration and nourishing products, which may be in the form of shampoos, conditioners, hair conditioners, hair sprays.
Hydrolyzed keratin is widely used in personal care products.
A major chunk of Hydrolyzed keratin is composed of cysteine which is known to fill the gaps in the cuticle and repair it.


When used in hair protection sprays, Hydrolyzed keratin makes hair more resilient to heat damage.
Hydrolyzed keratin increases the tensile strength of the hair and ensures that breakage is minimised.
Hydrolyzed keratin is added to serums which are marketed to prevent the occurrence of split ends.
With continuous use, Hydrolyzed keratin makes the hair strands thicker and the overall hair look voluminous.


Hydrolyzed keratin is increasingly been used in hair treatment products like hair masks, conditioners, and salon treatments.
Hydrolyzed keratin is used as ANTISTATIC, FILM FORMING, HAIR CONDITIONING, HUMECTANT, SKIN CONDITIONING
Hydrolyzed keratin is used in Personal care, Hair care and cosmetics
Hydrolyzed keratin is used in Concentrations of 1-5% and added to the diluent phase of mixtures


Revitalizes the hairs natural protective layer and rebuilds tensile strength
Reduces hair damage from harsh chemicals
Hydrolyzed Keratin is a Hair Conditioning ingredient and helps to increase the softness or smoothness of hair, reduce tangles, and to reduce surface roughness.


Functions of Hydrolyzed keratin are Revitalizing, moisturizing, luster restoring, protection,
increases the amount of hair cystine and tensile strength.
Applications are Hair shampoo, conditioner, hair care treatment,


Skin care treatment of Hydrolyzed keratin include serum and moisturizer.
Cosmetic Uses of Hydrolyzed keratin are cleansing agents, hair conditioning, skin conditioning, surfactants
In hair conditioners, keratin supplements the lack of building components of a hair.


Hydrolyzed keratin's particles build themselves in damaged places of hair sheath subsequently strengthening them and increasing their elasticity as well as volume by means of the creation of protective colloids which protect the hair against harmful effects of oxidative (paints) and reducing preparations.


Hydrolyzed keratin is used in hair and nail conditioners, hair sprays, nail enamels, bubble baths, after-shaves, anti-dandruff shampoos and preparations, preparations for stylization of hair, permanent wave, bleaching preparations, preparations in the form of foam, regenerative hair conditioners (a type of "fluid hair").
Applied For Nourishment & Moisturization


Hydrolyzed keratin is a protein fragment that not only coats but also penetrates the hair shaft to replace missing keratin in microscopic gaps along the hair shaft, resulting in smooth and shiny hair.
Hydrolyzed keratin is not meant to be used for straightening your hair.
Hydrolyzed keratin helps rebuild the hair’s natural protective layer, making it stronger and more elastic while reducing hair breakage and splitting.


Hydrolyzed keratin increases the diameter of hair fibers, giving a fuller appearance to fine and thin hair.
Hydrolyzed keratin also increases the hair’s ability to retain moisture and reduces frizz and flyaways caused by dryness.
If your expensive salon keratin treatment has started to wear off, adding hydrolyzed keratin to your shampoo, conditioner or leave-in conditioner could help extend the time between salon straightening services.


Hydrolyzed keratin can be incorporated into all kinds of water-based hair care products.
You can add it to your shampoo and conditioner at a concentration between 0.2%-3%.
The optimum use rate may vary depending on the condition of your hair.
Make sure not to exceed the maximum concentration of up to 3%, because if you use too much, your hair can become stiff or look greasy.


Hydrolyzed keratin can also be added to your deep conditioner and left in your hair under a shower cap for about an hour.
Make sure to rinse thoroughly and follow up with a moisturizing conditioner.
Hydrolyzed Keratin Cas No: 69430-36-0 is used in all kinds of Hair care products, such as shampoo, conditioner.


-Usage rate: 1-10% at the cool down phase.
Try Hydrolyzed keratin at a percentage:
*5% for frequent use hair conditioner
*8-10% in reinforced dry hair intensive treatment mask
*3% in hand and nail cream!
*0.5-2.0% (1.0% recommended for hair rejuvenation in shampoo or conditioner formula, rinse-off type and recommended 2.0% for leave-on hair treatment/mask)


-Antistatic:
Reduces static electricity by neutralizing the electrical charge on a surface
-Film forming agent:
Produces a continuous film on the skin, hair or nails
-Hair conditioner:
Leaves hair easy to comb, supple, soft and shiny and/or gives volume, lightness and shine


-Humectant:
Maintains the water content of a cosmetic in its packaging and on the skin
-Skin conditioning agent:
Keeps the skin in good condition


-Skin care:
Hydrolyzed keratin is used as a humectant to keep the moisture intact and skin conditioning agent, to maintain softness, suppleness.
Hydrolyzed keratin is also used as a film forming agent to produce a continuous film on the skin as well as nails


-Cosmetic Uses:
*antistatic agents
*emulsion stabilisers
*hair conditioning
*viscosity controlling agents
*In nail enamels and conditioners:
Hydrolyzed keratin regenerates the structure of damaged plaque and results in its hardening and strengthening, prevents hair breaking and splitting as well as bears extreme similarity to proteins existing in skin and hair.


-Hydrolyzed keratin is especially recommended for the production of conditioners for the following types of nails:
*yellow with discolorations,
*damaged and splitting,
*thin and easily cracking,
*breaking,
*with dried and cracking epidermis as well as preparations hiding nail irregularities and becoming the basis for enamel.



HOW HYDROLYZED KERATIN WORKS:
Hydrolyzed keratin works by getting absorbed into the hair because of its low molecular weight.
Hydrolyzed keratin works by replenishing the hair of the protein loss and by depositing the proteins on it.
Hydrolyzed keratin is usually used in the range of 1%-5%.
Hydrolyzed keratin is soluble in water and insoluble in oil.



HOW TO USE- HYDROLYZED KERATIN:
Add to the water phase of any formula.
Must be added at room temperature or temperature below 40oC to avoid masking its effectiveness.
Add emulsifying ingredients and then add solvents.



HYDROLYZED KERATIN - NATURE:
Hydrolyzed keratin is a 3 kinds of branched chain amino acid L A LEUCINE, L isoleucine, L_valine composition of the sterilization solution, is colorless or almost colorless clear liquid.
Each lOOmL contains L-leucine 1.65g,L-isoleucine 1. 35g, and L-valine 1.26g.
The pH was 5.5-7.5. In addition to the high content, other properties are with a 3 amino acid injection a 3 41-like.



WHY YOU SHOULD BE USING HYDROLYZED KERATIN PROTEIN?
Hair consists of about 80% Keratin.
Keratin will strengthen all 3 layers of the hair i.e. Cuticle, Cortex and Medulla.
Keratin protein is the strongest of the proteins found in hair products.



WHY IS HYDROLYZED KERATIN PROTEIN IMPORTANT?
Hydrolyze means to break up into smaller pieces, in a nonspecific manner, basically to fragment the protein.
The Hydrolyzed Keratin proteins have been broken down in order to deposit itself on to the hair shaft in the regions of porosity and damage due to it’s low molecular structure.

The Hydrolyzed Keratin Proteins are small enough to go beyond the cuticle and penetrate the hair shaft due to it's low molecular weight; therefore, reducing damage.
Since hair is made from Keratin, it is by far the best protein to treat hair that has been damaged by chemicals and heavy manipulation.

Keratin is known to replace the amino acid cysteine, which is lost during chemical processing.
The cysteine bridges are broken, during the chemical process, resulting in a damaged and weakened hair.
Hydrolyzed Keratin increases the amount of cysteine available to the hair, thus, minimizing damage and increasing tensile strength.

Keratin has a unique strength and protective quality.
Hydrolyzed Keratin Protein particles are known to fill in the cracks along damaged areas in the hair shaft subsequently strengthening the hair, increasing elasticity and volume.

Due to its moisture binding capabilities, Hydrolyzed Keratin Protein increases the moisture content in the hair, restoring luster, body, and increasing manageability.
Hydrolyzed Keratin Protein Is Not A permanent ‘fix’ for damaged hair/split ends! Hydrolyzed Keratin Protein is ‘attracted’ to the hair and it will still rinse off the hair eventually - in fact rather quickly.



HOW CAN YOU REPAIR DAMAGED HAIR?
By applying protein reconstructor treatments (with Keratin) to your hair regularly to maintain the desired result.
By conditioning with products that contain Hydrolyzed Keratin Protein, you are effectively replacing the missing and damaged keratin from your hair, thus, keeping the hair strong, resilient, as well as pliable.



HYDROLYZED KERATIN - STANDARD:
Hydrolyzed keratin is a fully methylated cyclic siloxane containing a repeating unit [-(c h 3) 2sk), wherein> is 4, 5, or 6, or a mixture thereof. (C2H6OSi).
The content shall not be less than 98.0% based on the total amount of cyclomethyl silicone 4, cyclomethyl silicone 5 and cyclomethyl silicone 6.
The unit containing cyclomethyl silicone shall be 95.0% to 105 of the labeled amount, 0%.



HYDROLYZED KERATIN - TRAIT:
Hydrolyzed keratin is colorless and transparent oily liquid.



CHEMICAL PROPERTIES OF HYDROLYZED KERATIN:
Hydrolyzed keratin is derived from wool and is a light yellow to amber transparent liquid with a special odor.
Hydrolyzed keratin must be treated with a special biological treatment, into a short peptide, can be bioavailable.
The treated keratin is a potential source of high quality protein with high nutritional value and stable quality.



PREPARATION OF HYDROLYZED KERATIN:
Hydrolyzed Keratin may be prepared from sheep wool.
The wool is first washed to remove soil and debris and then boiled to remove residual oils.
Next, the wool is enzyme-hydrolyzed under mild conditions for 4-6 hours.
When the target molecular weight is reached, the pH is adjusted to neutralize the enzyme.

The resultant solution is a mixture of Hydrolyzed Keratin fractions with a molecular weight of ~ 1000 Da.
The solution may be diluted to produce a 30% active material.
Hydrolyzed Keratin products (MW = 310 Da, 320 Da, and 11,000 Da, respectively) are prepared by acidic, alkaline and/or enzymatic hydrolysis of sheep wool until the molecular weight reaches the target range.



HOW TO USE HYDROLYZED KERATIN
How to use hydrolyzed keratine in haircare?
If you are struggling with dry, dull, rough, and coarse hair, then you should consider incorporating hair keratin into your haircare regime.
Hydrolyzed Keratin can be used in two ways to improve the structure of your hair, giving it a fuller appearance.
You can apply a store-brought protein treatment or go for a DIY protein treatment.

-Store-brought keratin & protein treatment:
Most store-bought Keratin or protein treatments have moisturizing ingredients in the formulation so that you can apply the treatment easily to hair.
To ensure that hair is not over-processed:
Follow the instructions on the label.
You may need a processing cap, hooded dryer, or processing cap for specific treatments.
Make sure you have everything you need.
Don't exceed the time or measurements recommended.

-DIY keratin treatment:
The best part of DIY keratin treatment is that you can customize it according to your needs.
For the DIY hair keratin treatment, follow these simple steps:
The first step is to decide the hair product you'll add hydrolyzed Keratin to deep conditioner shampoo, conditioner, or all three.
If you add protein to your hair products, you can use them as you usually would.
Measure how much hair product you'll use after you have chosen the product.
Calculate the amount of protein you need based on the recommended concentration.
You will need between 2 and 10 ml hydrolyzed Keratin.
After you have determined the portion size, measure it, pour it into the desired container, and mix it up.
Apply the mixture evenly to your hair. Avoid touching the scalp to prevent clogged pores.
Rinse your hair thoroughly after the time is up.



HOW TO CHOOSE HYDROLYZED KERATIN IN HAIRCARE?
You have two options for choosing hydrolyzed Keratin for your hair- Store-Brought Keratin Treatment & DIY Keratin Treatment.
You can choose anyone depending upon the requirements of your hair.
Due to time constraints, If you want to go hassle-free, you can go for a store-bought one, or if you want to customize the keratin treatment according to your haircare needs, you can choose a DIY hair keratin treatment.



WHERE DOES HYDROLYZED KERATIN COME FROM?
Keratin is naturally produced within the body, just like biotin.
Biotin, a water-soluble vitamin, assists in the metabolism of protein which provides a foundation for keratin.
You can also find keratin in food sources.
Foods high in vitamin C, biotin, lean protein and whole grains are keratin-rich and improve keratin in your nails and hair.
Topical products like nail treatments, lotions, shampoo and conditioner also contain hydrolyzed keratin.



WHAT DOES HYDROLYZED KERATIN DO TO YOUR HAIR?
When you use hydrolyzed keratin on your hair topically, it helps fill the minor gaps throughout the hair shaft, including its three layers - the medulla, cortex and cuticle.
It’s like pouring cement into a crack.
When the broken down protein fills these microscopic gaps, hair gets the strength to minimize damage from chemical treatments, heat styling, mechanical manipulation and the sun.



BENEFITS OF HYDROLYZED KERATIN:
Hydrolyzed keratin can repair and condition damaged hair.
Hydrolyzed keratin strengthen hair fibers and reduce hair breakage.
Hydrolyzed keratin are often added to hair coloring products for even color absorption.

Hydrolyzed keratin protects the hair from the damaging effects of permanent bleaching, waving, and straightening products.
Hydrolyzed keratin improves the texture and natural structure of the hair and forms a protective coating to shield the strands.
Hydrolyzed keratin boosts hair moisture and elasticity and protects it from heat and photo-damage .

Hydrolyzed keratin retains water content in the cortex by bonding with residual amino acids produced by hair proteins .
Research shows that hydrolyzed keratin can help stimulate hair growth.
Protein hydrolysates protect the hair from chemical and environmental aggressors to prevent hair damage.

Hydrolyzed keratin also helps seal hair cuticles.
This minimizes frizz and prevents flyaways.
The amino acids from hydrolyzed proteins neutralize the negative electrical charge on the hair to eliminate frizz and friction.

Hydrolyzed keratin has a similar amino acid structure to that of natural human hair.
Hydrolyzed keratin is known to improve the tensile strength of damaged hair.
Hydrolyzed keratin maintains the health and youth of hair and nails and strengthens them: hair is shinier, less brittle, hair loss is slowed down, nails are more supple.

Hydrolyzed keratin strengthens skin by protecting from free radicals, and softens it and makes it more supple.
Reduces frizz, shedding and breakage.
Increases smoothness and elasticity with its moisture-binding abilities.
Essentially, hydrolyzed keratin helps rebuild the hair’s natural protective layer from the inside by increasing the diameter of each strand.

This gives a fuller appearance and replaces lost protein.
When hair treatments contain broken down or hydrolyzed keratin, it creates a protective barrier on the hair and simultaneously imparts shine.
Hydrolyzed keratin works on the skin too, and it restores moisture and improves the elasticity of the skin.

Hydrolyzed keratin's moisturizing properties make shampoos and conditioners that contain hydrolyzed keratin a go-to option for those with brittle, dry or limp hair.
Hydrolyzed keratin is an excellent choice to tame unruly hair and make it more manageable.

As hair is made from keratin, Hydrolyzed keratin is one of the best proteins to treat hair that’s heavily manipulated or chemically damaged.
Usually, when hair undergoes chemical processes, the amino acid cysteine breaks down and results in weakened and damaged hair.
Keratin is known to replace this lost cysteine.

Hydrolyzed keratin increases cysteine content, which increases tensile strength and minimizes damage.
Hydrolyzed keratin also increases volume, strengthens your hair, and restores luster.
Simply put, hydrolyzed keratin protein gets the job done because it has a low molecular weight.

Hydrolyzed Keratin can penetrate the hair cuticle.
This helps Hydrolyzed Keratin to take effect with more potency than say, something that merely sits on top of the hair.
Because Hydrolyzed keratin has a low molecular weight, Hydrolyzed keratin can penetrate the hair cuticle.

Helps repair damaged, broken and processed hair and helps hair grow.
Pure keratin oil is a protein that provides protection from the harmful rays of the sun.
Hydrolyzed keratin shows a straightening effect on hair that is electrified, swells and does not take shape easily.

Hydrolyzed keratin is applied directly to the hair.
To put it briefly, drinkable hydrolyzed keratin is a unique option for you to achieve the results you want in hair and nail health.
Hydrolyzed keratin can penetrate down to the lowest layer of hair and nails.

Hydrolyzed keratin can easily reach the cavities of the three layers that make up the hair - the medulla, cortex and cuticle.
By filling these gaps, Hydrolyzed keratin enables the hair to develop defense against external factors and increases its durability.
While protecting it from possible damage, Hydrolyzed keratin brings the hair that has lost its vitality back to life and makes them look brighter.

Hydrolyzed keratin strengthens the hair and prevents possible hair loss and breakage.
Hydrolyzed keratin repairs the dry and lifeless look created by dangerous sun rays, chemical treatments and hair styling that requires high heat.
Hydrolyzed keratin improves hair texture.

Thus, the problem of electrification is reduced in the hair, which has a smoother texture.
Hydrolyzed keratin increases the density of the hair.
Because by adding a new protein to replace the lost protein, Hydrolyzed keratin supports the protective layer of the hair from the inside and gives it a fuller appearance.

In addition to its positive effects that strengthen the hair, Hydrolyzed keratin also increases the durability of the nails.
Hydrolyzed keratin prevents breakage and weakness while extending the nails.
By repairing the damage caused by chemical applications such as permanent nail polish on the nails, Hydrolyzed keratin allows the nails to regain their former vitality.

Hydrolyzed keratin contributes to the healing process of thinned, damaged and dull nails that have lost their lively and shiny appearance.
Fights hair loss and promotes hair growth.
Helps restore life, volume and density to your hair.

Reduces frizz and smoothens hair.
Improves hair texture and adds shine instantly.
Free from silicone and other nasty toxins.

Suitable for all hair types.
Hair Fiber Reconstruction
Break strength

Healthy strands
Softness
Silkyness

Extra Brightness
Thermal protection
Supports hair brightness, density, and volume by bonding with hair strands.

Supports healthy, lustrous-looking hair.
Helps strengthen, nourish, and hydrate hair.

*Strengthens and protects:
When hydrolyzed keratin is used topically on the hair, it helps fill the minor gaps throughout the hair shaft, including its three layers known as the cuticle, cortex, and medulla.
Filling these microscopic gaps with broken-down protein helps to strengthen hair's structure, thereby improving its overall elasticity.

*Reduces damage:
Hydrolyzed keratin minimizes the damaging effects of sun exposure, heat styling, chemical treatments, and combing hair—tangled tresses, especially.

*Fights frizz:
Studies show that hydrolyzed keratin can improve hair's texture so that it looks and feels smoother.
In other words, Hydrolyzed Keratin's a frizz-fighting machine.

*Softens hair:
After chemical treatments that use hydrolyzed keratin, hair will feel softer and bouncier.

*Moisturizes:
Hydrolyzed Keratin acts as a humectant, which draws moisture into the hair.

*Increases density:
Hydrolyzed Keratin also helps to rebuild the natural protective layer of hair from the inside by replacing lost protein and increasing each strand’s diameter, which gives it a fuller appearance.

*Moisturizes hair:
Hydrolyzed keratin keeps the strands well moisturized for a longer period of time.

*Repairs the damaged strands:
In the damaged hair, the amino acid-cysteine breaks down which leads to damaged and brittle hair, hydrolyzed keratin protein increases the cysteine content in the hair shaft, thus repairing the damaged strands.

*Tames frizzy hair:
Hydrolyzed keratin conditions the dry and frizzy hair, makes it more manageable.

*Adds shine to hair:
Hydrolyzed keratin forms a thin protective film over the hair, adding shine to the strands.

*Increases tensile strength of hair:
Hydrolyzed keratin makes the hair soft and improves the elasticity, prevents breakage and split ends.

*Strengthens:
The application of hydrolyzed Keratin topically can fill in the small gaps along the hair shaft.
This includes the three layers of the cuticle, cortex, and medulla. Keratin helps fill these minor gaps along the hair shaft, strengthening the hair and improving its overall elasticity.

*Reduces damage:
Hydrolyzed keratin forms a protective layer on the surface of the hair, protecting it from heat and extreme climatic conditions, and reducing the chances of hair damage.

*Fights frizz:
Hydrolyzed Keratin can make your hair soft and frizz-free by keeping it hydrated and well-conditioned.

*Moisturizes:
A powerful humectant hydrolyzed Keratin is effective in keeping your hair well moisturized.

*Improves hair density:
Hydrolyzed keratin forms a protective layer by filling the gaps, replacing the lost protein, and enhancing the overall diameter of the hair, thus improving its density.



MECHANISM OF HYDROLYZED KERATIN:
A triple novelty and superiority compared to other keratin products:
The different proteins that make up the Hydrolyzed keratin are separated, with very specific activities.
They are intact and therefore similar to native keratin.
The activity of the cysteine is fully restored.



CHEMICAL PROPERTIES OF HYDROLYZED KERATIN:
Hydrolyzed keratin is a large protein molecule that is broken down after a chemical process in a manner such that it can penetrate the hair cuticle.
Hydrolyzed keratin is sourced from a larger keratin molecule.
Keratin is broken down by splitting its bond with the addition of hydrogen and hydroxide (water).
At the end of the chemical process, the keratin is reduced into smaller fragments that the hair can absorb, thanks to its lower molecular weight.



HOW TO USE HYDROLYZED KERATIN?
Before choosing a product containing hydrolyzed keratin, it is necessary to pay attention to the function of the other components it contains and how it results.
In addition, instead of turning to products that will cause you to get a superficial care; you need to choose healthy methods that nourish your hair and nails from the inside.

At this point, you can take advantage of the power of nutritional supplements.
Drinkable hydrolyzed keratin supplement, suitable for all hair types, that you can use daily, is the shortest way to revitalize your hair and nails!
Sincere support has a positive effect on your health in general, while also helping you achieve the aesthetic appearance and durability you desire.

Whether your hair is difficult to style, dry or damaged, include hydrolyzed keratin in your haircare arsenal.
In no time will your hair look and feel shinier, softer, fuller and stronger.
Hydrolyzed Keratin provides moisturizing benefits for both hair and skin.

Can be used in hair treatment, shampoo, conditioner, styling, leave-in, bodywash, body lotion, body treatments, cleanser, toner, facial moisturizer, face, treatment, mascara, lipstick, color cosmetics, makeup foundation.
You can find many hair care products like shampoos, conditioners, hair masks, and serums containing Hydrolyzed keratin.
Use these products regularly to improve the hair texture and tensile strength and repair damaged hair.

*DIY Hair Products:
Add a concentration of 0.5-3% of hydrolyzed keratin to your regular shampoo, conditioner, or hair mask to condition and protect the hair.

*Deep Conditioning Treatment:
You can add 0.5-3% concentration of hydrolyzed keratin to any deep conditioning treatment.
Apply the product, put on a shower cap, and leave the treatment on overnight.
Wash it off in the morning.



HAIR TYPE CONSIDERATIONS:
Hydrolyzed keratin is beneficial for most hair types, but will have more benefits for people with curly, kinky, dry, or damaged hair.
High porosity hair types that have been weakened from chemical processes like color treatments, chemical relaxers, or sun damage benefit from keratin treatments.
The hydrolyzed keratin will fill the gaps in the hair strands that are weak.
Hydrolyzed keratin is a powerful ingredient, so it shouldn’t be applied as often as, say, a moisturizing deep conditioner.



IS HYDROLYZED KERATIN GOOD FOR CURLY HAIR?
Curly and kinky hair is porous and brittle and has a weak hair structure.
Hydrolyzed keratin can easily penetrate curly hair and improve its protein content to strengthen the strands and enhance the hair structure.
Hydrolyzed keratin may help enhance curl definition, so Hydrolyzed keratin is often suggested to be used in DIY hair masks and products.
Curly hair is more prone to damage and dryness, and hydrolyzed keratin can help minimize these issues.
Hydrolyzed keratin makes curly hair more manageable and frizz-free.
Hydrolyzed keratin also improves hair color and shine.



IS HYDROLYZED KERATIN VEGAN?
Hydrolyzed keratin is not vegan.
Keratin is derived from feathers, wool, nails, and other parts of animals.
However, hydrolyzed protein can be synthesized from the amino acid extracted from soy, wheat, and corn.
It is not be as effective as animal-derived keratin and may not restore the damaged hair structure.



PHYSICAL and CHEMICAL PROPERTIES of HYDROLYZED KERATIN:
Boiling Point: 214.8°C at 760 mmHg
Melting Point: 31.5°C
pH: 5.5-7.5
Solubility: Soluble in water
Physical state: solid
Colour: various
Odour: characteristic
pH (value): not applicable
Melting point/freezing point: 354 °C
Initial boiling point and boiling range: 116 °C
Flash point: 12 °C
Evaporation rate: not determined
Flammability (solid, gas): this material is combustible, but will not ignite readily
Explosion limits of dust clouds: not determined

Vapour pressure: not determined
Density: not determined
Vapour density: this information is not available
Relative density: information on this property is not available
Solubility(ies): not determined
Partition coefficient - n-octanol/water (log KOW): this information is not available
Auto-ignition temperature: not determined
Viscosity: not relevant (solid matter)
Explosive properties: none
Oxidising properties: none
pH value: 5.0-5.8.
Contains: 20-23% of protein
Molecular weight: 1,100-3,300 Dal
Derived: From Sheep's Wool

Ph: 5.0 - 7.5
Moisture: 7% Max.
Ash: 6% Max.
Protein: 90% Min.
Density: 0.2g/Ml Min.
Heavy Metal: 10ppm Max.
Lead: 1ppm Max.
Arsenic: 1ppm Max.
Mercury: 0.5ppm Max.
Average Molecular Weight: 2000da Max.
Total Bacterias: Coliforms: Salmonella: Absent /25g
Molds And Yeasts: Storage Condition: Keep Package Sealed Under Cool And Dry Place
Shelf Life: Two Years



FIRST AID MEASURES of HYDROLYZED KERATIN:
-General notes:
Take off immediately all contaminated clothing.
Never give anything by mouth.
-Following inhalation:
Provide fresh air.
-Following skin contact:
Rinse skin with water/shower.
-Following eye contact:
Remove contact lenses, if present and easy to do.
Continue rinsing.
Irrigate copiously with clean, fresh water for at least 10 minutes, holding the eyelids apart.
-Following ingestion:
Rinse mouth with water.



ACCIDENTAL RELEASE MEASURES of HYDROLYZED KERATIN:
-Environmental precautions:
Keep away from drains, surface and ground water.
-Methods and material for containment and cleaning up:
*Advice on how to contain a spill:
Covering of drains, Take up mechanically.
*Advice on how to clean up a spill:
Take up mechanically.
-Other information relating to spills and releases:
Place in appropriate containers for disposal.



FIRE FIGHTING MEASURES of HYDROLYZED KERATIN:
-Extinguishing media:
*Suitable extinguishing media:
Water, Foam, ABC-powder



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROLYZED KERATIN:
-Exposure controls:
*Appropriate engineering controls:
General ventilation.
-Individual protection measures (personal protective equipment):
*Eye/face protection:
Wear eye/face protection.
*Hand protection:
Wear protective gloves.
*Respiratory protection:
Particulate filter device (EN 143).
-Environmental exposure controls:
Use appropriate container to avoid environmental contamination.
Keep away from drains, surface and ground water.



HANDLING and STORAGE of HYDROLYZED KERATIN:
-Precautions for safe handling:
*Advice on general occupational hygiene:
Wash hands after use.
Do not eat, drink and smoke in work areas.
Never keep food or drink in the vicinity of chemicals.
Never place chemicals in containers that are normally used for food or drink.
Keep away from food, drink and animal feedingstuffs.



STABILITY and REACTIVITY of HYDROLYZED KERATIN:
-Chemical stability:
The material is stable under normal ambient and anticipated storage and handling conditions of temperature and pressure.



SYNONYMS:
HP (eluent)
Promois WK-F
Nutrilan Keratin W
K-D
Keratide
qua, Laurdimonium Hydroxypropyl Hydrolyzed
INSTANT BCAA
KERATIN (5% IN WATER)
Proteinhydrolysat
Hydrolysed protein
HYDROLYSED KERATINE
Keratin hydrolyzate
Branched amino acid
CL245
from Wool
Keratin hydrozylates (powder)
Keratins, hydrolyzates
Keratins, hydrolyzates
aminomethylpropanol salt of the condensation product of isostearic acid chloride with hydrolyzed keratin
hydrolyzed animal keratin
extrapone cashmere GW (Symrise)
extrapone cashmere GW N (Symrise)
crotein cashmere
crotein cashmere PE
crotein HKP powder
crotein K
crotein WKP
kerasol
keratin amino acids
keratin hydrolysate
keratin hydrolyzed
keratin, hydrolyzed
keratins, hydrolyzates
BCAA
Cattle hair
Proteinhydrolysat
Hydrolyzed keratin
HYDROLYZED KERATIN
Keratin hydrolyzed
Keratin, hydrolyzed
Keratin hydrolyzate
Compound amino acid
HYDROLYSED KERATINE
Keratins, hydrolyzates
Hydrolyzed animal keratin
Keratins,cattle horn,saponified and neutralized
Keratins, cattle horn, saponified and neutralized


HYDROLYZED KERATIN PROTEIN

Hydrolyzed keratin protein is a cosmetic and personal care ingredient derived from keratin, a fibrous protein that is a fundamental structural component of hair, skin, and nails in humans and animals.
The hydrolysis process breaks down the large keratin protein molecules into smaller fragments, called peptides, or individual amino acids.
This hydrolyzed form of keratin is used in various hair and skin care products due to its purported benefits for strengthening, conditioning, and nourishing hair and skin.

CAS Number: 69430-36-0
EC Number: 274-001-1

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APPLICATIONS


Hydrolyzed keratin protein finds extensive application in hair care products, including shampoos and conditioners, to improve hair strength and manageability.
Hydrolyzed keratin protein is commonly used in leave-in hair treatments, offering continuous nourishment and protection against environmental stressors.

Salon treatments often incorporate hydrolyzed keratin for professional-grade hair repair and rejuvenation.
Hydrolyzed keratin protein is a key ingredient in hair masks, providing an intensive conditioning experience for damaged or brittle hair.

Styling products such as hair serums and creams utilize hydrolyzed keratin to impart a glossy finish and control frizz.
Volumizing hair products often feature hydrolyzed keratin to enhance the structural integrity of individual hair strands.

Hydrolyzed keratin protein is prevalent in products designed for color-treated hair, helping maintain vibrancy and protect against color fading.
Certain nail care formulations include Hydrolyzed keratin protein to strengthen and nourish nails, promoting overall nail health.
Anti-aging skincare products may incorporate Hydrolyzed keratin protein for its potential to improve skin texture and hydration.

Hydrolyzed keratin protein's film-forming properties make it suitable for hair styling products, offering hold and structure.
In hair serums and oils, hydrolyzed keratin contributes to a lightweight and non-greasy formulation for easy application.

Scalp treatments often utilize hydrolyzed keratin to nourish the scalp and promote a healthy environment for hair growth.
Hydrolyzed keratin protein-infused hair sprays provide a protective barrier, helping to shield hair from humidity and environmental factors.
Products designed for chemically treated hair, such as permed or relaxed hair, may contain hydrolyzed keratin for repair and strengthening.

Hydrolyzed keratin protein is used in the formulation of heat protectant sprays to minimize damage caused by styling tools.
Hair primers and pre-styling products often feature hydrolyzed keratin to create a smooth canvas for styling.

Hydrolyzed keratin protein is incorporated into detangling sprays and leave-in conditioners to ease the combing and brushing of hair.
Hydrolyzed keratin protein is utilized in hair restructuring treatments, providing long-lasting benefits for damaged or over-processed hair.
Certain skincare formulations may include hydrolyzed keratin for its moisturizing properties and potential skin barrier support.

Hydrolyzed keratin protein is found in hair volumizing foams, contributing to lift and body without compromising hair health.
Conditioners for curly or textured hair may contain Hydrolyzed keratin protein to enhance curl definition and reduce frizz.
Hydrolyzed keratin protein is used in certain hair-repairing capsules or ampoules for targeted treatment of specific hair concerns.
Products formulated for fine or thinning hair often incorporate Hydrolyzed keratin protein to enhance thickness and volume.

Hair-nourishing leave-in creams and lotions frequently feature Hydrolyzed keratin protein for sustained benefits throughout the day.
Hydrolyzed keratin protein's versatility allows its inclusion in a wide array of hair and skincare products, addressing diverse concerns and preferences.

Hydrolyzed keratin protein is a common ingredient in split-end repair products, aiming to mend and prevent split ends for healthier-looking hair.
Hydrolyzed keratin protein is featured in deep conditioning treatments, providing an extra layer of hydration and repair for dry or damaged hair.

Hydrolyzed keratin protein can be found in hair primers, creating a smooth foundation for subsequent styling products.
Anti-frizz hair serums often leverage Hydrolyzed keratin protein to control frizz and promote smoother, more manageable hair.

Products designed for frequent heat styling, such as flat irons or curling wands, may contain hydrolyzed keratin for thermal protection.
Hydrolyzed keratin protein is utilized in volumizing mousses, contributing to enhanced fullness and body in the hair.

Hydrolyzed keratin protein is a key component in split-end menders, helping to temporarily seal and strengthen damaged hair tips.
Certain hair-repairing masks use hydrolyzed keratin alongside other nourishing ingredients for a comprehensive treatment.
Hydrolyzed keratin protein is incorporated into color-enhancing shampoos and conditioners, preserving the vibrancy of colored hair.

Hydrolyzed keratin protein is a popular choice in lightweight hair lotions, providing a subtle and natural finish without weighing down the hair.
Hydrolyzed keratin protein is often present in hair-repairing oils, offering an extra boost of nourishment for dry or brittle hair.

Styling gels may contain Hydrolyzed keratin protein to provide structure and hold while maintaining a flexible and touchable finish.
Certain hair-thickening products feature Hydrolyzed keratin protein for added volume and thickness, particularly in fine or thinning hair.

Hydrolyzed keratin protein is included in hair glosses and shine sprays, contributing to a glossy and polished appearance.
Hydrolyzed keratin protein is used in detangling leave-in sprays, making combing and brushing more manageable, especially for tangled hair.
Hydrolyzed keratin protein can be found in overnight hair masks, offering prolonged repair and nourishment while sleeping.

In certain hair growth products, Hydrolyzed keratin protein may play a role in supporting a healthy scalp environment for optimal hair growth.
Hydrolyzed keratin protein is featured in 2-in-1 shampoo and conditioner formulations, providing convenience in a single product.
Hydrolyzed keratin protein is included in pre-shampoo treatments to offer a protective barrier before the cleansing step, especially for chemically treated hair.

Hydrolyzed keratin protein is found in hair-setting sprays, helping to maintain the structure and longevity of styled looks.
Certain frizz-control hair creams utilize hydrolyzed keratin to combat humidity and keep hair smoother for longer periods.
Hydrolyzed keratin protein is included in hair-fortifying supplements, aiming to support overall hair health from within.

Hydrolyzed keratin protein is utilized in protective hair serums for swimming, providing an additional layer of defense against chlorine and saltwater damage.
Hydrolyzed keratin protein may be present in hair perfumes or scented hair mists, combining fragrance with hair-nourishing properties.
In styling powders or dry shampoos, hydrolyzed keratin can contribute to texture and volume while refreshing the hair between washes.

Hydrolyzed keratin protein is a key ingredient in keratin-infused hair masks designed to repair and strengthen hair fibers.
Hydrolyzed keratin protein is often included in smoothing hair serums, contributing to the reduction of frizz and the promotion of sleek, polished hairstyles.

Curl-defining creams may incorporate Hydrolyzed keratin protein to enhance the natural curl pattern while providing moisture and structure.
Hydrolyzed keratin protein is utilized in scalp treatments to nourish the scalp and create an optimal environment for healthy hair growth.
Certain hair-repairing leave-in conditioners feature Hydrolyzed keratin protein for continuous protection and nourishment throughout the day.

Volumizing dry shampoos may contain Hydrolyzed keratin protein to add texture and fullness while refreshing the hair between washes.
Hydrolyzed keratin protein is included in split-end prevention sprays, acting as a proactive measure to minimize future damage.

Hydrolyzed keratin protein is present in specialized color-protecting hair oils, offering both color preservation and overall hair health benefits.
Hydrolyzed keratin protein is found in revitalizing hair tonics, promoting circulation and rejuvenating the scalp for healthier hair.

Leave-in detangling sprays often use Hydrolyzed keratin protein to ease the combing process and prevent breakage in tangled hair.
Hydrolyzed keratin protein is incorporated into hair-building fibers, helping to create the appearance of fuller and thicker hair.
Hydrolyzed keratin protein is used in hair primers for upstyling or intricate hairstyles, providing a smooth base for intricate styling.

Hydrolyzed keratin protein can be found in repairing hair balms, offering targeted care for specific damaged areas.
Hydrolyzed keratin protein is utilized in post-sun exposure hair masks, providing soothing and replenishing properties for sun-damaged hair.

Hydrolyzed keratin protein is a common component in hair-nourishing capsules, offering a concentrated dose of repair for damaged hair.
Hydrolyzed keratin protein is included in humidity-resistant hair sprays, helping to maintain styles in damp or humid conditions.

Hydrolyzed keratin protein is present in split-end binding lotions, temporarily sealing and reinforcing damaged hair tips.
Hydrolyzed keratin protein is incorporated into lightweight hair mousses, providing volume and structure without a heavy or sticky feel.

Hydrolyzed keratin protein can be found in multi-action hair creams, offering a combination of styling, repair, and protection.
Hydrolyzed keratin protein is used in UV-protective hair products, shielding the hair from the damaging effects of sun exposure.
Hydrolyzed keratin protein is featured in strand-strengthening hair elixirs, promoting resilience and reducing breakage.

Hydrolyzed keratin protein is included in sulfate-free clarifying shampoos, offering a gentle cleanse while maintaining hair's natural moisture.
Hydrolyzed keratin protein can be found in flexible-hold hair gels, providing structure without stiffness for versatile styling.

Hydrolyzed keratin protein is present in hair-setting lotions, aiding in the creation and maintenance of long-lasting curls or waves.
Hydrolyzed keratin protein is utilized in nourishing overnight hair serums, delivering reparative benefits while sleeping.

Hydrolyzed keratin protein is featured in lightweight hair foams, providing styling support while maintaining a natural feel.
Hydrolyzed keratin protein is commonly included in keratin-infused hair glosses, enhancing shine and promoting a polished appearance.

Hydrolyzed keratin protein can be found in rejuvenating hair tonics, contributing to scalp health and revitalizing hair follicles.
In split-end binding sprays, hydrolyzed keratin helps temporarily mend and strengthen damaged hair ends.

Hydrolyzed keratin protein is used in protective hair serums with added antioxidants, shielding hair from environmental damage.
Hydrolyzed keratin protein is present in nourishing hair lotions designed for daily use, offering continuous hydration and care.
Hydrolyzed keratin protein is included in quick-dry hair mists, providing a fast-setting solution for on-the-go styling.

Hydrolyzed keratin protein can be found in anti-breakage hair masks, fortifying strands to reduce breakage and improve elasticity.
Hydrolyzed keratin protein is utilized in lightweight hair powders for added texture and volume without weighing down the hair.
Hydrolyzed keratin protein is featured in revitalizing hair sprays, offering a refreshing burst of hydration throughout the day.

Hydrolyzed keratin protein is included in humidity-resistant hair balms, helping to combat frizz in damp or humid conditions.
Hydrolyzed keratin protein is present in styling creams for textured or curly hair, enhancing definition and manageability.
Hydrolyzed keratin protein is used in shine-enhancing hair oils, providing a luminous finish and promoting a healthy-looking sheen.

Hydrolyzed keratin protein can be found in hair-strengthening capsules, offering a targeted treatment for weakened areas.
Hydrolyzed keratin protein is incorporated into hair-repairing ampoules, delivering concentrated care for specific hair concerns.
Hydrolyzed keratin protein is featured in color-protecting hair primers, preserving vibrancy while preparing the hair for styling.

Hydrolyzed keratin protein is used in revitalizing dry shampoos, providing a quick refresh while maintaining hair health.
Hydrolyzed keratin protein can be found in flexible-hold hair sprays, allowing for natural movement while providing control.

Hydrolyzed keratin protein is included in strand-repairing leave-in conditioners, offering ongoing care for damaged or chemically treated hair.
Hydrolyzed keratin protein is present in nourishing hair creams for textured or natural hair, promoting moisture and definition.

Hydrolyzed keratin protein is used in multi-action hair serums, combining reparative, protective, and styling benefits in a single product.
Hydrolyzed keratin protein can be found in hair-building supplements, aiming to support overall hair health and growth.
Hydrolyzed keratin protein is featured in weightless hair tonics, providing scalp care and promoting a balanced environment for hair growth.

Hydrolyzed keratin protein is used in protective hair masks for swimmers, counteracting the effects of chlorine and saltwater.
Hydrolyzed keratin protein is incorporated into shine-enhancing hair mists, offering a subtle and radiant finish for styled hair.



DESCRIPTION


Hydrolyzed keratin protein is a cosmetic and personal care ingredient derived from keratin, a fibrous protein that is a fundamental structural component of hair, skin, and nails in humans and animals.
The hydrolysis process breaks down the large keratin protein molecules into smaller fragments, called peptides, or individual amino acids.
This hydrolyzed form of keratin is used in various hair and skin care products due to its purported benefits for strengthening, conditioning, and nourishing hair and skin.

The chemical composition of hydrolyzed keratin protein can vary depending on the source and specific manufacturing processes.
Keratin itself is rich in amino acids, including cysteine, methionine, arginine, and others, which contribute to its structural and functional properties.

Hydrolyzed keratin protein is often included in hair care formulations such as shampoos, conditioners, and treatments, as well as in skincare products like creams and lotions.
Hydrolyzed keratin protein is believed to help improve the appearance and health of hair by reinforcing its structure, increasing shine, and reducing frizz.
In skincare, Hydrolyzed keratin protein is sometimes used for its potential moisturizing and skin-conditioning properties.

Hydrolyzed keratin protein, a cosmetic ingredient, is derived from the structural protein keratin found in hair, skin, and nails.
Hydrolyzed keratin protein undergoes a hydrolysis process, breaking it down into smaller peptides for use in various beauty formulations.
Renowned for its strengthening properties, Hydrolyzed keratin protein is a staple in hair care products designed to fortify and rejuvenate strands.

When applied, Hydrolyzed keratin protein forms a protective film on the hair, reducing frizz and enhancing overall manageability.
Hydrolyzed keratin's amino acid profile mirrors that of natural hair, contributing to its affinity for bonding with damaged areas.

Hydrolyzed keratin protein is often incorporated into shampoos and conditioners to improve elasticity and promote a smoother texture.
In skincare, Hydrolyzed keratin protein may offer moisture-retention benefits, contributing to a softer and more supple complexion.

Hydrolyzed keratin protein's small molecular size allows it to penetrate the hair shaft, aiding in the repair of damaged cuticles.
Products containing Hydrolyzed keratin protein are sought after for their potential to revitalize chemically treated or heat-damaged hair.

Its ability to reinforce weak or brittle nails makes it a valued ingredient in certain nail care formulations.
Hydrolyzed keratin protein is known for its film-forming properties, which can help protect hair from environmental stressors.
The lightweight nature of Hydrolyzed keratin protein allows for easy absorption into the hair, ensuring deep nourishment.
Hydrolyzed keratin protein's affinity for hair's natural structure makes it an excellent choice for products targeting split ends and breakage.

Hydrolyzed keratin protein is often found in leave-in treatments, offering prolonged benefits for continuous hair health.
Beyond its reparative properties, it imparts a glossy finish to the hair, enhancing its natural luster.

Hydrolyzed keratin protein is compatible with various hair types, making it versatile in formulations for different textures and styles.
In certain skincare products, Hydrolyzed keratin protein contributes to a smoother skin surface and improved hydration.
Its ability to strengthen hair's structural integrity makes it a popular choice for products targeting volumizing effects.
Hydrolyzed keratin protein is often featured in professional salon treatments aimed at restoring and rejuvenating damaged hair.

For those with color-treated hair, products containing this protein may help extend the vibrancy of the color.
The inclusion of Hydrolyzed keratin protein in hair masks provides an intensive treatment for deep conditioning and repair.

Due to its water-soluble nature, Hydrolyzed keratin protein easily blends into various formulations without leaving a residue.
The application of hydrolyzed keratin-infused products can result in hair that feels smoother, softer, and more resilient.
Its biocompatibility with the skin makes it a sought-after ingredient for skincare products focusing on anti-aging benefits.
Hydrolyzed keratin protein's popularity in the beauty industry stems from its multifaceted benefits, addressing a spectrum of hair and skin concerns.



PROPERTIES


Boiling Point: 214.8°C at 760 mmHg
Melting Point: 31.5°C
pH: 5.5-7.5
Solubility: Soluble in water



FIRST AID


Inhalation:

If inhaled, move the person to fresh air.
If breathing difficulties persist, seek medical attention.


Skin Contact:

In case of skin contact, immediately remove contaminated clothing.
Wash the affected area thoroughly with soap and water.
If irritation or redness persists, seek medical advice.


Eye Contact:

In case of contact with eyes, flush the eyes gently with lukewarm water for at least 15 minutes, holding eyelids open.
Seek immediate medical attention if irritation persists.


Ingestion:

If hydrolyzed keratin is ingested, do not induce vomiting.
Rinse the mouth with water and seek immediate medical attention.
Provide the medical professional with information about the product.


General First Aid:

If a person is unconscious, not breathing, or experiencing severe symptoms, call emergency services immediately.
Provide the medical professional with information about the product, including the product name and any available safety data sheets.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear suitable protective clothing, including gloves and safety goggles, to prevent skin contact and eye exposure.
If handling in an area with potential inhalation exposure, use respiratory protection as needed.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
Avoid inhaling vapors or dust.

Avoid Contact:
Minimize skin contact with the substance.
Avoid eye contact.
In case of contact, rinse eyes thoroughly with water.

Hygiene Practices:
Wash hands thoroughly after handling.
Remove and wash contaminated clothing promptly.


Storage:

Temperature:
Store hydrolyzed keratin in a cool, dry place.
Avoid exposure to extreme temperatures or direct sunlight, as this may affect the stability of the substance.

Containers:
Store in containers made of materials compatible with the substance to prevent contamination.
Keep containers tightly closed when not in use.

Separation:
Store away from incompatible materials and substances.

Handling Precautions:
Follow good manufacturing practices (GMP) and use proper hygiene measures during handling to prevent contamination.

Labeling:
Ensure proper labeling of containers with the product name, hazard symbols, and relevant safety information.
HYDROLYZED MILK PROTEIN
Hydrolyzed milk protein; Protein hydrolysates, milk; Proteins, milk, hydrolysate. cas no: 8049-98-7
Hydrolyzed Polymaleic Anhydride
Hydrolyzed Polymaleic Anhydride; HPMA; (Z)-2-Butenedioic acid homopolymer; Hydrolyzed polymaleic anhydride; HPMA; PMA CAS NO: 26099-09-2
Hydrolyzed Polymaleic Anhydride (HPMA)
HPMA, PMA, Polymaleic Acid, Maleic Acid Homopolymer, Maleic Acid Polymer cas :26099-09-2
HYDROLYZED RICE PROTEIN
soy protein hydrolyzate; soy protein hydrolyzate with enzyme-modified lecithin; soyaline; soybean peptone cas no: 68607-88-5
HYDROLYZED SOY PROTEIN
manduline; hydrolyzed prunus amugdalus dulcis protein; hydrolysate of sweet almond cas no: 235433-31-5
HYDROLYZED SWEET ALMOND PROTEIN
HYDROLYZED WHEAT PROTEIN; Glutens, enzyme-modified; WHEATPROTEINHYDROLYSATE; Wheat gluten, enzyme-modified;HYDROYZED WHEAT PROTEIN; Hydrolyzed Wheat Protein Concentrate cas no: 70084-87-6
HYDROLYZED WHEAT PROTEIN
HYDROQUINONE; 1,4-Dihydroxybenzene; p-Dihydroxybenzene; 1,4-Benzenediol; Quinol; 1,4-benzenediol; p Benzendiol; Benzoquinol; 1,4-Hydroxybenzene; p-Hydroquinone; p-Dihydroxybenzene; 1,4-Benzendil; Aida; Black and White Bleaching Cream; Eldoquin; Elopaque; quinnone; 1, 4-dihydroxy-benzeen cas no: 123-31-9
HYDROLYZED WHEAT PROTEIN
Hydrolyzed wheat protein is an aqueous solution of a wheat protein hydrolysate that is obtained by the action of a selected enzyme pool which yields a high level of free amino acids and short peptides.
Hydrolyzed wheat protein provides high substantivity to hair and can impart hair repairing properties, improve the ease of hair combing in cleansing formulations and improve colour deposition and retention of dyes on hair.
Hydrolyzed wheat protein is miscible with water and compatible with surfactants, electrolytes, cationic polymers and most vegetable extracts.

CAS: 70084-87-6
EINECS/ELINCS No: 305-225-0

Hydrolyzed wheat protein is recommended for use in leave-on and rinse-off applications.
Hydrolyzed wheat protein is a powder derived from wheat through a chemical process called hydrolysis, which involves the reaction of the substance (in this case wheat protein) with water and an acid.
The process is necessary to make the wheat protein small enough to access keratin through cuticles breakage.

The protein will increase the tensile strength of the hair to make Hydrolyzed wheat protein less susceptible to breakage.
Hydrolyzed wheat protein also adds volume, texture and condition to the hair, preventing it from drying out and leaving it soft and silky.

Hydrolyzed wheat protein comes from the controlled enzymatic hydrolysis of wheat and is gluten free.
Hydrolyzed wheat protein is rich in proteins and amino acids, essential elements for a healthy metabolism.
Hydrolyzed wheat protein increases skin’s firmness and helps to form a film to retain moisture and provide luminosity.
Hydrolyzed wheat protein prevents the skin from drying out and diminishes the appearance of wrinkles.
Hydrolyzed wheat protein nourishes and repairs hair, detangles, provides shine and hydration.

Hydrolyzed wheat protein is basically small-sized protein molecules that are easily absorbed by the skin and hair to provide multiple benefits and nutrition.
Protein molecules in general are large in size so they are broken down to make them easily absorbed.
Hydrolyzed wheat protein ingredient comes in the form of an amber-colored liquid that is found in a wide range of beauty products - from moisturizers and shampoos to eye creams and cleansers.
Additionally, hydrolyzed wheat protein is not gluten-free, but since it is not supposed to be consumed, Hydrolyzed wheat protein is safe for use.

Origin
Hydrolyzed wheat protein is generally derived from wheat germ.
Hydrolyzed wheat protein is industrially produced following a short and simple process.
First water is added to a reaction kettle then an alkaline protease is stirred in to make a uniform mixture.
Wheat gluten protein powder is then added and alkaline is stirred in until the pH of the mixture reaches 9-10.
The hydrolyzing process then starts by adding trypsin and hydrolyzing the mixture for 30-80 minutes.
Once this process is completed, the mixture is filtered and spray dried to result in hydrolyzed wheat protein.

Uses
Hydrolyzed wheat protein is a skin-conditioning ingredient.
This is a neutralized alcohol-soluble wheat protein/ fatty acid condensate.
Hydrolyzed wheat protein can be found in skin tonics.
hydrolyzed wheat protein offers conditioning, moisturizing, and film-forming properties.
Hydrolyzed wheat protein is an effective moisturizer in skin care products, where it helps retain moisture in the skin.
Hydrolyzed wheat protein is almost always used as a replacement for hydrolyzed animal protein.
Hydrolyzed wheat protein is produced by an enzymatic hydrolysis of wheat gluten.

Benefits of Wheat Protein for Hair
Hydrolyzed wheat protein is a type of non-animal protein derived from wheat germ, like gluten or glutamine.
Garshick explains that Hydrolyzed wheat protein is more effective when applied topically if it is broken down into smaller proteins, known as hydrolyzed wheat protein, which can then pass through the hair cuticle.
Hydrolyzed wheat protein is thought to help hydrate and strengthen the hair and works by locking in moisture, Garshick explains.
This combination of hydration and strengthening is exactly what most products designed to treat hair damage promise.

Synonyms
Glutens, enzyme-modified
70084-87-6
DTXSID80894585
Wheat Protein, hydrolyzed
hydrolized wheat protein
HYDROLYZED WHEAT PROTEIN
Glutens, enzyme-modified
WHEATPROTEINHYDROLYSATE
HydrolyzedWheatProteinConcentrate
Wheat gluten, enzyme-modified
HYDROYZED WHEAT PROTEIN
HYDROLYZED WHEAT PROTEIN USP/EP/BP
Hydrolysis Wheat protein peptide
HYDROLYZED WHEAT PROTEINE
Hydrolyzed wheat protein is basically small-sized protein molecules that are easily absorbed by the skin and hair to provide multiple benefits and nutrition.
Protein molecules in general are large in size so they are broken down to make them easily absorbed.
Hydrolyzed wheat protein ingredient comes in the form of an amber-colored liquid that is found in a wide range of beauty products - from moisturizers and shampoos to eye creams and cleansers.

CAS: 70084-87-6
EINECS: 615-058-8

Synonyms:
HYDROLYZED WHEAT PROTEIN;Glutens, enzyme-modified;WHEATPROTEINHYDROLYSATE;HydrolyzedWheatProteinConcentrate;Wheat gluten, enzyme-modified;HYDROYZED WHEAT PROTEIN;HYDROLYZED WHEAT PROTEIN USP/EP/BP;Hydrolysis Wheat protein peptide

Additionally, hydrolyzed wheat protein is not gluten-free, but since it is not supposed to be consumed, it is safe for use.
Hydrolyzed wheat protein is generally derived from wheat germ.
Hydrolyzed wheat protein is industrially produced following a short and simple process.
First water is added to a reaction kettle then an alkaline protease is stirred in to make a uniform mixture.
Wheat gluten protein powder is then added and alkaline is stirred in until the pH of the mixture reaches 9-10.
The hydrolyzing process then starts by adding trypsin and hydrolyzing the mixture for 30-80 minutes.
Once this process is completed, the mixture is filtered and spray dried to result in hydrolyzed wheat protein.

Hydrolyzed wheat protein has moisturizing and film-forming properties and might be able to counteract the irritating effects of cleansing agents in cleansers and shampoos.
Hydrolyzed wheat protein can also condition and repair damaged hair leaving it soft, silky and smooth.

Physical form
Powder, white-yellowish to brown
Molecular weight
Molecular weight 0.1 – 90 kDa. Mostly between 25 and 90 kDa.
Solubility
Soluble in water

Uses
Hydrolyzed wheat protein has many benefits for the hair and skin.
The small molecules of this ingredient easily penetrate the surface and repair the tissues from deep within. Hydrolyzed wheat protein is used in many skin care and hair care products such as facial serums, lotions, and hair sprays.
Skin care: It tends to form a layer on the skin to prevent moisture loss and give a luminous feel to the skin.
It increases the firmness of the skin and prevents it from drying out.
Further, hydrolyzed wheat protein has anti-aging properties and reduces the appearance of fine lines and wrinkles on the skin.
Hair care: It is known for treating dry and damaged hair.
It provides deep moisture and strengthens hair shafts, thus reducing hair fall and breakage.
Products like hydrolyzed wheat protein shampoo make hair shinier and improve the overall texture.

Hydrolyzed wheat protein offers conditioning, moisturizing, and film-forming properties.
Hydrolyzed wheat protein is an effective moisturizer in skin care products, where it helps retain moisture in the skin.
Hydrolyzed wheat protein is almost always used as a replacement for hydrolyzed animal protein.
Hydrolyzed wheat protein is produced by an enzymatic hydrolysis of wheat gluten.

Because hydrolyzed wheat protein is so easily absorbed into your hair strands, they quickly swell with water and plump up.
As a result, your hair appears fuller and thicker, creating more volume.
This can make your wavy hair easier to style and give it that desired fullness that most of us in the wavy hair community love.
It’s also great for anyone who struggles with thinning hair.
HYDROQUINONE
Hydroquinone is produced by the oxidation of aniline or phenol, by the reduction of quinone, or from a reaction of acetylene and carbon monoxide.
Hydroquinone occurs naturally as a glucose ether, also known as arbutin, in the leaves of many plants and in fruits, as well as one of the agents used in the defense mechanism of the bombardier beetle, family Carabidae.
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.

CAS: 123-31-9
MF: C6H6O2
MW: 110.11
EINECS: 204-617-8

Synonyms
Hydroquinone;123-31-9;Benzene-1,4-diol;1,4-benzenediol;Quinol;1,4-Dihydroxybenzene;p-Benzenediol;p-Hydroquinone;p-Hydroxyphenol;4-Hydroxyphenol;p-Dihydroxybenzene;Benzoquinol;hydroquinol;Dihydroquinone;Eldoquin;p-Dioxybenzene;Solaquin forte;Eldopaque;Hydroquinole;Idrochinone;Tecquinol;Phiaquin;Benzohydroquinone;Hidroquinone;Arctuvin;Tequinol;Dihydroxybenzene;Eldopaque Forte;Eldoquin Forte;Derma-Blanch;Hydrochinon;Tenox HQ;Diak 5;Benzene, p-dihydroxy-;Hydrochinone;1,4-Dihydroxy-benzol;Artra;Usaf ek-356;1,4-Diidrobenzene;p-Dioxobenzene;1,4-Dihydroxybenzen;para-Dioxybenzene;para-Hydroquinone;NCI-C55834;Black and White Bleaching Cream;1,4-Dihydroxy-benzeen;para-Dihydroxybenzene;beta-quinol;HE 5;Pyrogentistic acid;Epiquin;Melanex;Sunvanish;Idrochinone [Italian];p-Dihydroquinone;alpha-hydroquinone;CHEBI:17594;NSC 9247;Hydrochinon [Czech, Polish];CCRIS 714;1,4-Dihydroxybenzen [Czech];1,4-Diidrobenzene [Italian];HSDB 577;DTXSID7020716;1,4-Dihydroxy-benzeen [Dutch];1,4-Dihydroxy-benzol [German];AI3-00072;CHEMBL537;UNII-XV74C1N1AE;NSC-9247;EINECS 204-617-8;XV74C1N1AE;UN2662;Hydroquinone (USP);Hydroquinone [USP];MFCD00002339;HQ;DTXCID70716;NSC9247;EC 204-617-8;Hydroquinone [UN2662] [Poison];1,4-Dihydroxybenzene (ring-d4);TRI-LUMA COMPONENT HYDROQUINONE;NCGC00015523-02;HYDROQUINONE COMPONENT OF TRI-LUMA;HYDROQUINONE (IARC);HYDROQUINONE [IARC];para-Hydroxyphenol;HYDROQUINONE (MART.);HYDROQUINONE [MART.];HYDROQUINONE (USP-RS);HYDROQUINONE [USP-RS];quinnone;Eldopacque;p-Phenylenediol;p Benzendiol;HYDROQUINONE (USP MONOGRAPH);HYDROQUINONE [USP MONOGRAPH];p-Quinol;1,4-Benzoquinol;CAS-123-31-9;SMR000059154;1,4-Hydroxybenzene;SR-01000075920;BUTYLHYDROXYANISOLE IMPURITY A (EP IMPURITY);BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY];4-DIHYDROXYBENZENE;hydroquinon;BQ(H);Hydroquinoue;Balancer;MedisilkeNight;Supermax;hydroq uinone;hydroquinone gr;MiracleFade;Reduced quinone;a-Hydroquinone

Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone is a white granular solid.
Substituted derivatives of this parent compound are also referred to as hydroquinones. The name "hydroquinone" was coined by Friedrich Wöhler in 1843.
Hydroquinone is a chemical compound used in various skincare products for its skin-lightening properties.
Hydroquinone is commonly used to treat hyperpigmentation, such as age spots, melasma, and acne scars, by inhibiting the production of melanin in the skin.
Hydroquinone works by disrupting the enzymatic processes involved in melanin production, leading to a lighter complexion over time.
Hydroquinone is available in various forms, including creams, gels, and serums, and is often used in combination with other skincare ingredients for enhanced effectiveness.
However, prolonged and excessive use of hydroquinone can lead to side effects such as skin irritation, redness, and potentially ochronosis, a condition characterized by blue-black pigmentation of the skin.
Therefore, it is important to use hydroquinone under the guidance of a healthcare professional and to follow the recommended usage instructions.

Hydroquinone Chemical Properties
Melting point: 172-175 °C(lit.)
Boiling point: 285 °C(lit.)
Density: 1.32
Vapor density: 3.81 (vs air)
Vapor pressure: 1 mm Hg ( 132 °C)
Refractive index: 1.6320
Fp: 165 °C
Storage temp: Store below +30°C.
Solubility: H2O: 50 mg/mL, clear
Pka: 10.35(at 20℃)
Form: Needle-Like Crystals or Crystalline Powder
Color: White to off-white
Odor: odorless
Water Solubility: 70 g/L (20 ºC)
Sensitive: Air & Light Sensitive
Merck: 14,4808
BRN: 605970
Exposure limits NIOSH REL: 15-min ceiling 2, IDLH 50; OSHA PEL: TWA 2; ACGIH TLV: TWA 2 (adopted).
Stability:: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, oxygen, ferric salts. Light and air-sensitive. Discolours in air.
InChIKey: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
LogP 0.59 at 20℃
CAS DataBase Reference 123-31-9(CAS DataBase Reference)
NIST Chemistry Reference: Hydroquinone(123-31-9)
IARC: 3 (Vol. 15, Sup 7, 71) 1999
EPA Substance Registry System: Hydroquinone (123-31-9)

Uses
Hydroquinone has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.

There are various other uses associated with its reducing power.
As a polymerisation inhibitor, exploiting its antioxidant properties, hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.
By acting as a free radical scavenger, hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.

Hydroquinone is a pigment-lightening agent used in bleaching creams.
Hydroquinone combines with oxygen very rapidly and becomes brown when exposed to air.
Although Hydroquinone occurs naturally, the synthetic version is the one commonly used in cosmetics.
Application to the skin may cause allergic reaction and increase skin sun sensitivity.

Production Methods
There are three current manufacturing processes for HQ: oxidative cleavage of diisopropylbenzene, oxidation of aniline, and hydroxylation of phenol.
Diisopropylbenzene is air oxidized to the intermediate diisopropylbenzene bishydroperoxide.
This hydroperoxide is purified by extraction and reacted further to form hydroquinone.
The purified product is isolated by filtration and packaged. The process can be almost entirely closed, continuous, computer-controlled, and monitored.
Hydroquinone can also be prepared by oxidizing aniline to quinone in the presence of manganese dioxide and sulfuric acid.
p-Benzoquinone is then reduced to Hydroquinone using iron oxide.
The resulting hydroquinone is crystallized and dried.
The process occurs in a closed system.
HQis also manufactured by hydroxylation of phenol using hydrogen peroxide as a hydroxylation agent.
The reaction is catalyzed by strong mineral acids or ferrous or cobalt salts.

Natural occurrences
Hydroquinones are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.
The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
This chamber is lined with cells that secrete catalases and peroxidases.
When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the hydroquinones into p-quinones.
These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.
Hydroquinone is thought to be the active toxin in Agaricus hondensis mushrooms.
Hydroquinone has been shown to be one of the chemical constituents of the natural product propolis.
Hydroquinone is also one of the chemical compounds found in castoreum.
Hydroquinone is gathered from the beaver's castor sacs.
HYDROQUINONE
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone is known for its ability to inhibit the production of melanin, the pigment responsible for skin, hair, and eye color.
Hydroquinone bleaches the skin, which can be helpful when treating different forms of hyperpigmentation.

CAS Number: 123-31-9
Molecular Formula: C6H6O2
Molecular Weight: 110.11
EINECS Number: 204-617-8

Synonyms: hydroquinone, Benzene-1,4-diol, 123-31-9, 1,4-benzenediol, Quinol, 1,4-Dihydroxybenzene, p-Benzenediol, p-Hydroquinone, p-Hydroxyphenol, 4-Hydroxyphenol, p-Dihydroxybenzene, Benzoquinol, Eldoquin, hydroquinol, Eldopaque, Phiaquin, p-Dioxybenzene, Solaquin forte, Dihydroquinone, Hydroquinole, Idrochinone, Tecquinol, Benzohydroquinone, Hidroquinone, Arctuvin, Tequinol, Dihydroxybenzene, Eldopaque Forte, Eldoquin Forte, Derma-Blanch, Hydrochinon, Tenox HQ, Diak 5, Benzene, p-dihydroxy-, Hydrochinone, 1,4-Dihydroxy-benzol, Artra, Usaf ek-356, 1,4-Diidrobenzene, p-Dioxobenzene, 1,4-Dihydroxybenzen, para-Dioxybenzene, para-Hydroquinone, NCI-C55834, Pyrogentistic acid, Black and White Bleaching Cream, 1,4-Dihydroxy-benzeen, para-Dihydroxybenzene, beta-quinol, HE 5, Epiquin, Sunvanish, Idrochinone [Italian], p-Dihydroquinone, alpha-hydroquinone, para-Hydroxyphenol, CHEBI:17594, NSC 9247, Hydrochinon [Czech, Polish], CCRIS 714, 1,4-Dihydroxybenzen [Czech], 1,4-Diidrobenzene [Italian], quinnone, Eldopacque, HSDB 577, DTXSID7020716, p-Phenylenediol, 1,4-Dihydroxy-benzeen [Dutch], 1,4-Dihydroxy-benzol [German], p Benzendiol, p-Quinol, AI3-00072, CHEMBL537, UNII-XV74C1N1AE, NSC-9247, 1,4-Benzoquinol, EINECS 204-617-8, XV74C1N1AE, UN2662, 1,4-Hydroxybenzene, Hydroquinone [USP], MFCD00002339, HQ, BQ(H), DTXCID70716, Black & White Bleaching Cream, NSC9247, EC 204-617-8, Hydroquinone [UN2662] [Poison], 1,4-Dihydroxybenzene (ring-d4), Hydroquinone (USP), TRI-LUMA COMPONENT HYDROQUINONE, NCGC00015523-02, HYDROQUINONE COMPONENT OF TRI-LUMA, HYDROQUINONE (IARC), HYDROQUINONE [IARC], HYDROQUINONE (MART.), HYDROQUINONE [MART.], HYDROQUINONE (USP-RS), HYDROQUINONE [USP-RS], HYDROQUINONE (USP MONOGRAPH), HYDROQUINONE [USP MONOGRAPH], CAS-123-31-9, SMR000059154, SR-01000075920, BUTYLHYDROXYANISOLE IMPURITY A (EP IMPURITY), BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY], 4-DIHYDROXYBENZENE, hydrokinone, hydroquinon, Hidroquinona, Hydrokinon, Hydroquinoue, Accutin, Elopaque, hydroq uinone, hydroquinone gr, p-fenilenediol, p-hidroquinona, p-hidroxifenol, Reduced quinone, a-Hydroquinone, p-Dioxibenceno, 4-hidroxifenol, p-Diphenol, p-Hydroxybenzene, b-Quinol, 4-Benzenediol, Dihydroxybenzen e, 14-Benzoquinol, p-Dihidroxibenceno, Hydroquinone, HQ, .beta.-Quinol, 1,4 benzenediol, 1,4-Bencenodiol, Hydroquinone,(S), p-dihydroxy benzene, p -Dihydroxybenzene, PLQ, 1,4-Benzendil, Artra (Salt/Mix), HYDROP, .alpha.-Hydroquinone, 1 4-p-Benzenediol, Hydroquinone (8CI), phenol derivative, 4, 1 4-Dihydroxybenzene, 1,4-Dihidroxibenceno, 4-hydroxyphenyl alcohol, Spectrum_001757, 4e3h, HDQ (CHRIS Code), PYROGENTISIC ACID, SpecPlus_000769, 1,4-Dihydrobenzoquinone, ELDOQUIN (TN), HYDROQUINONE BAKER, hydroquinone for synthesis, Spectrum2_001672, Spectrum3_000656, Spectrum4_000633, Spectrum5_001430, HYDROQUINONE [MI], Lopac-H-9003, WLN: QR DQ, bmse000293, D03UOT, D08LQA, Epitope ID:116206, HYDROQUINONE [HSDB], HYDROQUINONE [INCI], HYDROQUINONE [VANDF], 1,4-Dihydroxybenzene Quinol, Lopac0_000577, SCHEMBL15516, BSPBio_002291, KBioGR_001246, KBioSS_002237, 1,4-Dihydroxybenzene, XIII, MLS000069815, MLS001074911, BIDD, DivK1c_006865, HYDROQUINONE [WHO-DD], Hydroquinone, LR, >=99%, SPECTRUM1504237, Hydrochinon(CZECH, POLISH), SPBio_001883, BDBM26190, Hydroquinone, puriss., 99.0%, KBio1_001809, KBio2_002237, KBio2_004805, KBio2_007373, KBio3_001511, Benzene-1,4-diol (Hydroquinone), BENZENE, 1,4-DIHYDROXY-, HMS1922H15, HMS2093E08, HMS3261D16, HYDROQUINONE [ORANGE BOOK], LS-23, Pharmakon1600-01504237, HY-B0951, Hydroquinone [UN2662] [Poison], Tox21_110169, Tox21_202345, Tox21_300015, Tox21_500577, CCG-39082, NA2662, NSC758707, s4580, STK397446, UN3435, AKOS000119003, Tox21_110169_1, AM10548, DB09526, LP00577, NSC-758707, SDCCGSBI-0050559.P003, UN 2662, Hydroquinone, ReagentPlus(R), >=99%, Hydroquinone, USP, 99.0-100.5%, NCGC00015523-01, NCGC00015523-03, NCGC00015523-04, NCGC00015523-05, NCGC00015523-06, NCGC00015523-07, NCGC00015523-08, NCGC00015523-09, NCGC00015523-10, NCGC00015523-11, NCGC00015523-12, NCGC00015523-13, NCGC00015523-19, NCGC00090880-01, NCGC00090880-02, NCGC00090880-03, NCGC00090880-04, NCGC00090880-05, NCGC00254037-01, NCGC00259894-01, NCGC00261262-01, BP-21160, Hydroquinone, ReagentPlus(R), >=99.5%, SBI-0050559.P002, Hydroquinone, SAJ first grade, >=99.0%, EU-0100577, FT-0606877, H0186, Hydroquinone, SAJ special grade, >=99.0%, EN300-18053, Hydroquinone, meets USP testing specifications, C00530, D00073, H 9003, AB00053361_08, Quinol; 1,4-Benzenediol; 1,4-Dihydroxybenzene, Q419164, J-004910, J-521469, SR-01000075920-1, SR-01000075920-4, Q27102742, Z57127551, 094CADDB-59BF-4EDF-B278-59791B203EA2, F1908-0167, Hydroquinone, certified reference material, TraceCERT

Hydroquinone is a topical skin-bleaching agent used in the cosmetic treatment of hyperpigmented skin conditions.
The effect of skin lightening caused by hydroquinone is reversible when exposed to sunlight and therefore requires regular use until desired results are achieved.
Various preparations are available including creams, emulsions, gels, lotions and solutions.

Ultimately, this causes a decrease in the number of melanocytes and decreased transfer of melanin leading to lighter skin.
Hydroquinone is a potent skin-lightening agent that is often used to diminish skin discolouration and promote an even skin tone.
Hydroquinone functions by reducing the production and increasing the degradation of melanin pigments in the skin.

This two-pronged action not only helps lighten the skin but also ensures a more uniform skin tone.
Hydroquinone is a depigmenting agent used to lighten areas of darkened skin such as freckles, age spots, chloasma, and melisma caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.
Hydroquinone decreases the formation of melanin in the skin.

Hydroquinone, a colorless, hexagonal prism, has been reported to be a good antimitotic and tumor-inhibiting agent.
Hydroquinone is a reducing agent used in a photographic developer, which polymerizes in the presence of oxidizing agents.
The reactivity of the hydroxyl groups of hydroquinone is weakly acidic, similar to that of other phenols.

The resulting conjugated base undergoes easy O-alkylation to give mono- and diethers.
Similarly, Hydroquinone is highly sensitive to ring substitution by Friedel-Crafts reactions such as alkylation.
This reaction is exploited to obtain popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).

The useful dye quinizarin is produced by diacylation of Hydroquinone with phthalic anhydride.
Hydroquinone undergoes oxidation under mild conditions to give benzoquinone.
Some naturally occurring Hydroquinone derivatives exhibit such reactivity; an example of this is coenzyme Q.

Industrially, this reaction is used both with Hydroquinone itself and more often with its derivatives in which an OH is present.
Colorless Hydroquinone and benzoquinone, a bright yellow solid, are co-crystallized in a 1:1 ratio to give a dark green crystal.
A charge-transfer complex (melting point 171 °C) called quinhydron (C6H6O2·C6H4O2) is formed.

This complex dissolves in hot water, where the two molecules dissociate in solution.
Hydroquinone has a variety of uses, mainly related to its action as a water-soluble reducing agent.
Hydroquinone is a key ingredient in most black and white photo developers for film and paper.

Hydroquinone methol reduces silver halides to elemental silver.
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone is a dihydroxybenzene compound, and it is also known as p-dihydroxybenzene.

Hydroquinones chemical structure consists of two hydroxyl groups (-OH) attached to a benzene ring.
This structure makes it an effective inhibitor of melanin production in the skin.
Hydroquinone works by inhibiting the activity of an enzyme called tyrosinase, which is involved in the production of melanin. By reducing the amount of melanin produced, hydroquinone can help lighten areas of hyperpigmentation or dark spots on the skin.

In skincare products, hydroquinone is typically applied topically in the form of creams, gels, or lotions.
Hydroquinone is available in both over-the-counter (OTC) and prescription-strength formulations, with the latter being more potent.
Prescription-strength hydroquinone is often used for more severe cases of hyperpigmentation or melasma.

While hydroquinone can be effective in treating skin conditions, it is important to use it with caution.
Prolonged or excessive use of hydroquinone may lead to side effects such as skin irritation, redness, or a condition called ochronosis, which can result in a bluish-black pigmentation of the skin.
This is one reason why some countries have regulations and restrictions on the use of hydroquinone in cosmetics.

Hydroquinone is produced by the oxidation of aniline or phenol, by the reduction of quinone, or from a reaction of acetylene and carbon monoxide.
There are also various other uses associated with reducing power.
Leveraging its antioxidant properties as a polymerization inhibitor, hydroquinone prevents the polymerization of acrylic acid.

Hydroquinone, cyanoacrylate and other monomers susceptible to radical-initiated polymerization.
Hydroquinone serves to extend the shelf life of photosensitive resins by acting as a free radical scavenger.
Hydroquinone can lose a hydrogen cation from either hydroxyl group to form a diphenolate ion.

The disodium diphenolate salt of hydroquinone is used as an alternative comonomer unit in polymer production.
Skin depigmentation Hydroquinone is used as a topical application to reduce skin discoloration in skin whitening.
Hydroquinone does not have the same predisposition to cause dermatitis as methol.

This is a prescription-only ingredient in some countries under the Directives, including member states of the European Union.
In 2006, the United States Food and Drug Administration revoked the previous approval of hydroquinone and recommended that it be banned.
The FDA officially banned Hydroquinone in 2020 as part of a larger reform of the over-the-counter drug review process.

The FDA stated that Hydroquinone cannot be ruled out as a potential carcinogen.
Hydroquinone is typically used for a limited duration, and once the desired results are achieved, users are advised to discontinue its use.
Hydroquinone can make the skin more sensitive to the sun.

Hydroquinone's essential to use sunscreen and sun protection measures when using hydroquinone-containing products to prevent further hyperpigmentation and sun damage.
While hydroquinone is generally considered safe when used as directed, it can cause side effects in some individuals.
Common side effects may include skin dryness, redness, irritation, and a condition called "exogenous ochronosis," which can result in darkening of the skin in the treated areas.

This is more commonly associated with long-term or misuse of hydroquinone.
Before using hydroquinone, especially in higher concentrations or for more severe skin conditions, it's advisable to consult with a dermatologist.
They can recommend an appropriate treatment plan and monitor your progress.

In recent years, there has been growing interest in alternative skin-lightening agents, such as kojic acid, alpha arbutin, and licorice root extract, which are sometimes used as alternatives or in conjunction with hydroquinone for hyperpigmentation treatment.
Studies in which adult rats have found increased rates of tumors, including thyroid follicular cell hyperplasia, anisokaryosis (change in nucleus size), mononuclear cell leukemia, hepatocellular adenomas and renal tubule cell adenomas.
The Safe Cosmetics Campaign also drew attention to concerns.

Numerous studies have revealed that taking Hydroquinone by mouth can cause exogenous ochronosis, a disfiguring disease in the body, which blue-black pigments are deposited in the skin; but skin preparations containing this ingredient applied topically.
The FDA classified hydroquinone as a safe product in 1982; however, it was generally considered safe and effective (GRASE).
Additional studies have been proposed within the scope of the National Toxicology Program (NTP) in order to determine whether there is a risk from the use of hydroquinone to humans.

NTP evaluation showed some evidence of long-term carcinogenic and genotoxic effects.
In some countries, hydroquinone is available both by prescription and over-the-counter (OTC).
The concentration of hydroquinone in OTC products is typically lower than in prescription-strength products.

Hydroquinone is generally not recommended for long-term, continuous use.
Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone's essential to consult with a healthcare provider or dermatologist for safe alternatives during pregnancy and breastfeeding.

In some cases, dermatologists may recommend combination therapies that include hydroquinone alongside other skin-lightening agents, such as retinoids or corticosteroids, to enhance the effectiveness of the treatment and reduce potential side effects.
Hydroquinone is typically used for a limited duration, often in cycles of a few months, to target specific areas of hyperpigmentation.
After achieving the desired results, users may be advised to switch to maintenance therapy, which typically involves milder products to prevent recurrence of hyperpigmentation.

Hydroquinone typically works gradually, and improvement in skin tone and reduction of hyperpigmentation may take several weeks to months, depending on the severity of the condition.
Individuals with darker skin tones may be more prone to side effects like skin irritation or darkening (exogenous ochronosis) when using hydroquinone.
Dermatologists often recommend lower concentrations or alternative treatments for individuals with darker skin.

Hydroquinone is applied topically to treat disorders characterized by excessive melanin in the epidermis, such as melasma.
In the United States, nonprescription skin-lightening products contain hydroquinone at concentrations of 2% or less; higher concentrations are available by prescription.
Hydroquinone is marketed most aggressively to women of color for its whitening ability in skin creams.

The chemical is allowed in personal care products in the United States in concentrations up to two percent.
Hydroquinone is a white granular solid.
Hydroquinone is most commonly used in skin lighteners, products heavily marketed towards women of color.

Hydroquinone is linked to cancer and organ-system toxicity.
Hydroquinone is frequently found in skin-lightening products like bleaching creams.
Hydroquinone works by limiting your production of melanin, the hormone that darkens your skin.

While some people use it to lighten their darker skin, hydroquinone creams are most commonly used to lighten small, dark patches like sunspots or hyperpigmentation.
Creams with Hydroquinone as an ingredient are an excellent non-surgical aesthetic procedure to help you achieve the skin they have always wanted.
Hydroquinone is also a skin irritant in humans.

Chronic (long-term) occupational exposure to hydroquinone dust can result in eye irritation, corneal effects, and impaired vision.
No information is available on the reproductive, developmental, or carcinogenic effects of hydroquinone in humans.
There was some evidence of carcinogenic activity in orally-exposed rodents.

Increased skin tumor incidence has been reported in mice treated dermally.
Hydroquinone has not classified hydroquinone for carcinogenicity.
Hydroquinone are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.

The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
In the manufacturing industry Hydroquinone may occur include bacteriostatic agent, drug, fur processing, motor fuel, paint, organic chemicals, plastics, stone coating, and styrene monomers.
Hydroquinone is a chemical compound that is commonly used in skincare products and cosmetics for its skin-lightening and depigmenting properties.

Hydroquinone is considered a skin-lightening agent and is used to treat various skin conditions related to hyperpigmentation, such as melasma, age spots, freckles, and post-inflammatory hyperpigmentation (dark spots left after skin inflammation or injury).
Melanin is the pigment in skin that gives it a brown color.
Hydroquinone is a chemical that a person can use to lighten their skin tone.

Hydroquinone is available as a cream, gel, lotion, or emulsion.
Hydroquinone is generally safe to use, but some people may experience side effects, such as dry skin.
Hydroquinone is frequently found in skin-lightening products like bleaching creams.

Hydroquinone works by limiting your production of melanin, the hormone that darkens skin.
While some people use it to lighten their darker skin, hydroquinone creams are most commonly used to lighten small, dark patches like sunspots or hyperpigmentation.
Hydroquinone produces reversible lightening of the skin by interfering with melanin production by the melanocytes.

Specifically, inhibition of the enzymatic conversion of tyrosine to DOPA (dihydroxyphenylalanine) results in the desired chemical reduction of pigment.
The name "hydroquinone" was coined by Friedrich Wöhler in 1843.
As a result, Hydroquinone is used topically in products such as creams, lotions, and serums to treat skin conditions like hyperpigmentation, melasma, age spots, and other forms of uneven skin tone.

Hydroquinone can help reduce the appearance of dark spots and promote a more even complexion.
Substituted derivatives of this parent compound are also referred to as hydroquinones.
Hydroquinone is a white granular solid.

Hydroquinone works by inhibiting the activity of an enzyme called tyrosinase, which is involved in the production of melanin, the pigment responsible for the color of the skin, hair, and eyes.
By blocking this enzyme, hydroquinone reduces the production of melanin, leading to a gradual lightening of the skin in areas where hyperpigmentation is present.
Hydroquinone is a skin-lightening agent.

Hydroquinone occurs naturally as a glucose ether, also known as arbutin, in the leaves of many plants and in fruits, as well as one of the agents used in the defense mechanism of the bombardier beetle, family Carabidae.
Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.

Melting point: 172-175 °C(lit.)
Boiling point: 285 °C(lit.)
Density: 1.32
vapor density: 3.81 (vs air)
vapor pressure: 1 mm Hg ( 132 °C)
refractive index: 1.6320
Flash point: 165 °C
storage temp.: Store below +30°C.
solubility: H2O: 50 mg/mL, clear
pka: 10.35(at 20℃)
form: Needle-Like Crystals or Crystalline Powder
color: White to off-white
Odor: odorless
Water Solubility: 70 g/L (20 ºC)
Sensitive: Air & Light Sensitive
Merck: 14,4808
BRN: 605970
Henry's Law Constant (x 10-9 atm?m3/mol): Exposure limits NIOSH REL: 15-min ceiling 2, IDLH 50; OSHA PEL: TWA 2; ACGIH TLV: TWA 2 (adopted).
Stability: Stable. Combustible, Incompatible with strong oxidizing agents.
InChIKey: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
LogP: 0.59 at 20℃

Hydroquinone has been shown to be one of the chemical constituents of the natural product propolis.
Hydroquinone is also one of the chemical compounds found in castoreum.
The detection of Hydroquinone along with resorcinol and phenol in air samples by synchronous fluorescence method has been proposed.

The electrochemical oxidation of Hydroquinone has been studied using cyclic and differential pulse voltammetry.
Hydroquinones enthalpies of sublimation, vaporization and fusion have been reported.
Hydroquinone may be used to synthesize bicyclic phosphonate derivative by reacting with phosphonic dichloride.

Unlike skin lightening surgery, hydroquinone creams are a cosmetic procedure that can be undertaken in the comfort of these home after the initial consultation with your dermatologist.
Hydroquinone is used as a developing agent in photography and as an antioxidant in rubber and food.
Tinnitus (ringing in the ears), dizziness, headache, nausea, vomiting, dyspnea, erosion of the gastric mucosa, edema of internal organs, cyanosis, convulsions, delirium, and collapse may result from the ingestion of a large amount of hydroquinone in humans.

When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the hydroquinones into p-quinones.
These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.
Hydroquinone is produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and naturally in certain plant species, Hydroquinone is a phenol derivative with antioxidant properties that can cause toxicity in several organs, notably the kidney.
Hydroquinone is used as a topical treatment for skin hyperpigmentation and in various cosmetic products, it is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems.

Hydroquinone appears as light colored crystals or solutions.
Hydroquinone may irritate the skin, eyes and mucous membranes.
Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other.

Hydroquinone has a role as a cofactor, a carcinogenic agent, an Escherichia coli metabolite, a human xenobiotic metabolite, a skin lightening agent, an antioxidant and a mouse metabolite. Hydroquinone is a benzenediol and a member of hydroquinones.
Hydroquinone is used as a developing agent in black-and-white photography, lithography, and x-ray films.
Hydroquinone is added to a number of industrial monomers to inhibit polymerization during shipping, storage, and processing.

Hydroquinones are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.
The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the hydroquinones into p-quinones.

These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.
Hydroquinone is produced industrially in two main ways.
The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene.

Hydroquinone reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.
A second route involves hydroxylation of phenol over a catalyst.
The conversion uses hydrogen peroxide and affords a mixture of hydroquinone and its ortho isomer catechol (benzene-1,2-diol): C6H5OH + H2O2 ⟶C6H4(OH)2 + H2O

A potentially significant synthesis of hydroquinone from acetylene and iron pentacarbonyl has been proposed Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.
Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.
Hydroquinone and its derivatives can also be prepared by oxidation of various phenols. Examples include Elbs persulfate oxidation and Dakin oxidation.

Hydroquinone was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.
Hydroquinone is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.

This medicine works by blocking the process in the skin that leads to discoloration.
Hydroquinone is a chemical that a person can use to lighten their skin tone.
Hydroquinone is available as a cream, gel, lotion, or emulsion.

Hydroquinone is a chemical that bleaches the skin.
Hydroquinone can come as a cream, emulsion, gel, or lotion.
A person can apply these products directly to the skin.

Creams that contain hydroquinone are available with a prescription from a doctor.
People may use hydroquinone as a form of treatment for hyperpigmentation skin conditions, wherein some areas of skin grow darker than surrounding areas.
Hydroquinone is a depigmenting agent used to lighten areas of darkened skin such as freckles, age spots, chloasma, and melisma caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.

Hydroquinone decreases the formation of melanin in the skin.
Melanin is the pigment in skin that gives it a brown color.
Hydroquinone is also known as 1,4-dihydroxy-benzene.

Hydroquinone is also used as an intermediate to produce antioxidants for rubber and food.
Hydroquinone is thought to be the active toxin in Agaricus hondensis mushrooms.
Due to concerns about its safety and potential side effects, some individuals seek alternative skin-lightening ingredients, such as alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), vitamin C, and natural extracts like licorice root or kojic acid.

These ingredients may offer skin-brightening benefits without the potential risks associated with hydroquinone.
The use of hydroquinone in cosmetics and skincare products is regulated by health authorities in different countries.
In some places, Hydroquinone may be available over-the-counter, while in others, it requires a prescription.

Some countries have banned or restricted Hydroquinone is use in cosmetics due to concerns about safety.
Before using products containing hydroquinone, it's advisable to consult with a dermatologist or healthcare professional to determine the most appropriate and safe treatment plan for your specific skin concerns. They can guide you on how to use hydroquinone effectively and minimize the risk of side effects.

Production Methods:
There are three current manufacturing processes for HQ: oxidative cleavage of diisopropylbenzene, oxidation of aniline, and hydroxylation of phenol.
Hydroquinone is air oxidized to the intermediate diisopropylbenzene bishydroperoxide.
This hydroperoxide is purified by extraction and reacted further to form hydroquinone.

The purified Hydroquinone is isolated by filtration and packaged.
The process can be almost entirely closed, continuous, computer-controlled, and monitored.
Hydroquinone can also be prepared by oxidizing aniline to quinone in the presence of manganese dioxide and sulfuric acid.

p-Benzoquinone is then reduced to Hydroquinone using iron oxide.
The resulting hydroquinone is crystallized and dried.
The process occurs in a closed system.

Hydroquinone is also manufactured by hydroxylation of phenol using hydrogen peroxide as a hydroxylation agent.
The reaction is catalyzed by strong mineral acids or ferrous or cobalt salts.

Uses:
Hydroquinone produces reversible lightening of the skin by interfering with melanin production by the melanocytes.
Hydroquinone has an industrial use resulting in manufacture of another substance (use of intermediates).
Hydroquinone is used in the following areas: printing and recorded media reproduction and formulation of mixtures and/or re-packaging.

Hydroquinone is used for the manufacture of: chemicals and plastic products.
Release to the environment of Hydroquinone can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.
Hydroquinone is used in the following products: photo-chemicals.

Other release to the environment of Hydroquinone is likely to occur from: indoor use as reactive substance.
Hydroquinone has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.

There are various other uses associated with its reducing power.
As a polymerisation inhibitor, exploiting its antioxidant properties, hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.
Hydroquinone is a pigment-lightening agent used in bleaching creams.

Hydroquinone combines with oxygen very rapidly and becomes brown when exposed to air.
Although it occurs naturally, the synthetic version is the one commonly used in cosmetics.
Hydroquinone application to the skin may cause allergic reaction and increase skin sun sensitivity.

Hydroquinone is potentially carcinogenic and is associated with causing ochronosis, a discoloration of the skin.
The u.S. FDA has banned hydroquinone from oTC cosmetic formulations, but allows 4 percent in prescription products.
Hydroquinones use in cosmetics is prohibited in some european countries and in Australia.

Hydroquinone is a skin-lightening agent used topically for the treatment of hyperpigmentation.
Hydroquinone is used as a developing agent in black-and-white photography, lithography, and x-ray films.
Hydroquinone is also used as an intermediate to produce antioxidants for rubber and food.

Hydroquinone is added to a number of industrial monomers to inhibit polymerization during shipping, storage, and processing
Hydroquinone is primarily used to treat various forms of hyperpigmentation, including melasma, sunspots, age spots, and post-inflammatory hyperpigmentation.
Some individuals use hydroquinone for overall skin lightening to achieve a more even skin tone.

Hydroquinone is most commonly used to treat various forms of hyperpigmentation, which includes.
Hydroquinone is used skin condition characterized by dark patches on the face, often triggered by hormonal changes, pregnancy, or sun exposure.
Hydroquinone is used age Spots (Liver Spots): Dark spots that commonly appear on areas of the skin exposed to the sun, typically with age.

Hydroquinone is used small, brown spots on the skin, often related to sun exposure and genetics.
Hydroquinone is used dark spots or discoloration that remain after an inflammatory skin condition or injury, such as acne, eczema, or a wound.
Some individuals use hydroquinone for overall skin lightening to achieve a more even skin tone.

Hydroquinone can be used to address concerns about uneven pigmentation or dark areas on the skin.
Hydroquinone is sometimes used in combination with other dermatological treatments, such as retinoids or corticosteroids, to enhance its effectiveness in treating hyperpigmentation.
Dermatologists may recommend hydroquinone to prepare the skin for certain procedures, such as chemical peels or laser therapy, as it can help improve the uniformity of skin tone.

Hydroquinone has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.
Hydroquinone is used as a polymerisation inhibitor, exploiting its antioxidant properties, hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.

By acting as a free radical scavenger, hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.

The disodium diphenolate salt of hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.
Hydroquinone is most commonly used in skin lighteners, products heavily marketed towards women of color.

Hydroquinone is used in the following products: photo-chemicals, polymers, coating products, inks and toners and water treatment chemicals.
Hydroquinone is used in a cream or lotion formulation in a concentration of 1-5%.
Hydroquinone is often found in a combination formulation with other skin lightening agents such as topical retinoids (to increase efficiency) and low potency topical steroids (to reduce irritancy).

In New Zealand and many other countries, hydroquinone is only available on prescription, and may need to be compounded by the pharmacist.
Hydroquinone must be distinguished from monobenzyl ether of hydroquinone which can cause irreversible pigment loss.
Hydroquinone is a topical skin-bleaching agent used in the cosmetic treatment of hyperpigmented skin conditions.

The effect of skin lightening caused by hydroquinone is reversible when exposed to sunlight and therefore requires regular use until desired results are achieved.
Various preparations are available including creams, emulsions, gels, lotions and solutions.
Hydroquinone is available over the counter in a 2% cream and can be prescribed by your dermatologist in higher concentrations.

Health Hazard:
Hydroquinone is very toxic; the probable oral lethal dose for humans is 50-500 mg/kg, or between 1 teaspoon and 1 ounce for a 150 lb.
Hydroquinone is irritating but not corrosive.
Fatal human doses have ranged from 5-12 grams, but 300-500 mg have been ingested daily for 3-5 months without ill effects.

Exposures to hydroquinone in large quantities by accidental oral ingestion produce toxicity and poisoning.
The symptoms of poisoning include, but are not limited to, blurred speech, tinnitus, tremors, sense of suffocation, vomiting, muscular twitching, headache, convul- sions, dyspnea and cyanosis from methemoglobinemia, coma, and collapse from respira- tory failure.
Occupational workers should be allowed to work with protective clothing and dust masks with full-face or goggles to protect the eyes, and under proper management.

HYDROQUINONE
DESCRIPTION:

Hydroquinone is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones.



CAS NUMBER: 123-31-9

EC NUMBER: 204-617-8

MOLECULAR FORMULA: C6H6O2

MOLECULAR WEIGHT: 110.12



DESCRIPTION:

Hydroquinone appears as light colored crystals or solutions.
Hydroquinone may irritates the skin, eyes and mucous membranes.
Hydroquinone is mildly toxic by ingestion or skin absorption.
Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Hydroquinone has a role as a cofactor, a carcinogenic agent, an Escherichia coli metabolite, a human xenobiotic metabolite, a skin lightening agent, an antioxidant and a mouse metabolite.

Hydroquinone is a benzenediol and a member of hydroquinones.
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles.
Hydroquinone can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.
Hydroquinone has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity.

As a result of these concerns, hydroquinone has been banned in the EU and UK.
Hydroquinone is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.This medicine works by blocking the process in the skin that leads to discoloration.
Hydroquinone is a skin-lightening agent used topically for the treatment of hyperpigmentation.
Hydroquinone is used in a cream or lotion formulation in a concentration of 1-5%.
Hydroquinone is often found in a combination formulation with other skin lightening agents such as topical retinoids (to increase efficiency) and low potency topical steroids.

Hydroquinone is used as a developing agent in photography and as an antioxidant in rubber and food.
Hydroquinone is a Melanin Synthesis Inhibitor. The mechanism of action of hydroquinone is as a Melanin Synthesis Inhibitor. The physiologic effect of hydroquinone is by means of Depigmenting Activity.
Hydroquinone is frequently found in skin-lightening products like bleaching creams.
Hydroquinone works by limiting your production of melanin, the hormone that darkens your skin.

While some people use it to lighten their darker skin, hydroquinone creams are most commonly used to lighten small, dark patches like sunspots or hyperpigmentation.
Hydroquinone is produced by the oxidation of aniline or phenol, by the reduction of quinone, or from a reaction of acetylene and carbon monoxide.
Hydroquinone has been reported to be a good antimitotic and tumor-inhibiting agent.
Hydroquinone is a reducing agent used in a photographic developer, which polymerizes in the presence of oxidizing agents.
In the manufacturing industry, Hydroquinone may occur include bacteriostatic agent, drug, fur processing, motor fuel, paint, organic chemicals, plastics, stone coating, and styrene monomers.

Hydroquinone is a pigment-lightening agent used in bleaching creams.
Hydroquinone combines with oxygen very rapidly and becomes brown when exposed to air.
Although Hydroquinone occurs naturally, the synthetic version is the one commonly used in cosmetics.
Application to the skin may cause allergic reaction and increase skin sun sensitivity.
Hydroquinone is potentially carcinogenic and is associated with causing ochronosis, a discoloration of the skin.
Hydroquinone interferes with the production of the pigment melanin by epidermal melanocytes through at least two mechanisms.

Hydroquinone competitively inhibits tyrosinase, one of the principal enzymes responsible for converting tyrosine to melanin, and it selectively damages melanocytes and melanosomes (the organelles within which melanin is stored).
Hydroquinone is used in photography developers (black and white, X-ray, and microfilms), in plastics, in hair dyes as an antioxidant and hair colorant.
Hydroquinone is found in many skin bleaching creams.

Creams with hydroquinone as an ingredient are an excellent non-surgical aesthetic procedure to help you achieve the skin you have always wanted. Unlike skin lightening surgery, hydroquinone creams are a cosmetic procedure that can be undertaken in the comfort of your own home after the initial consultation with your dermatologist.
If you have dark patches or old sunspots, creams with hydroquinone can lighten them and – when combined with other suitable skincare ingredients – can help your skin recover from sun damage.
Hydroquinone is a topical skin-bleaching agent used in the cosmetic treatment of hyperpigmented skin conditions.

The effect of skin lightening caused by hydroquinone is reversible when exposed to sunlight and therefore requires regular use until desired results are achieved. Various preparations are available including creams, emulsions, gels, lotions and solutions.
Hydroquinone is available over the counter in a 2% cream and can be prescribed by your dermatologist in higher concentrations.
Hydroquinone is used as an antioxidant in tire industry.
Hydroquinone is used as a small additive to prevent homopolymerization to all monomers in the liquid phase.

Hydroquinone is used as a barrier to polymerization in bone cement due to heat and light.
Hydroquinone is used in the photography sector in radiography and filmmaking.
Hydroquinone is an active substance used in creams that cause skin color in this sector.
Because of the side effects of hydroquinone such as skin irritation, cytotoxicity and exogenous ochronosis, it has been possible to develop alternative colorants.
Hydroquinone is an aromatic organic compound.

In the United States, Hydroquinone may be used as an active ingredient in OTC drug products.
When used as an active drug ingredient, the established name is Hydroquinone.
Hydroquinone is used as an inhibitor of polymerization.
Due to its outstanding photo developing properties, Hydroquinone is also used as a photo developer, and as a raw material in manufacturing dye intermediates.
Hydroquinone is produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and naturally in certain plant species, Hydroquinone is a phenol derivative with antioxidant properties that can cause toxicity in several organs.

Hydroquinone is used as a topical treatment for skin hyperpigmentation and in various cosmetic products.
Hydroquinone is metabolized mainly to glutathione conjugates and forms mutagenic DNA adducts in in-vitro systems.
Hydroquinone, also benzene-1,4-diol, is an aromatic organic compound which is a type of phenol.
Hydroquinone is commonly used as a biomarker for benzene exposure.
The presence of hydroquinone in normal individuals stems mainly from direct dietary ingestion, catabolism of tyrosine and other substrates by gut bacteria, ingestion of arbutin containing foods, cigarette smoking, and the use of some over-the-counter medicines.

Hydroquinone is a white, odorless, crystalline solid with an extremely low vapor pressure.
Hydroquinone is moderately soluble in water and highly soluble in alcohol.
Hydroquinone occurs in the environment as a result of anthropogenic processes, as well as in natural products from plants.
In the soil, hydroquinone is expected to biodegrade under aerobic conditions.
Hydroquinone may be removed from the soil by oxidation processes or by direct photolysis on the surface.
In the water, Hydroquinone would degrade under either aerobic or anaerobic conditions.

Hydroquinone can also slowly oxidize to quinone, which is more volatile.
In the air, hydroquinone undergoes photochemical degradation.
Hydroquinone is a skin lightening agent available as either a pharmaceutical or a cosmeceutical.
Hydroquinone's mechanism of action depends on its ability to inhibit tyrosinase synthesis, thereby inhibiting the production of melanin.
Hydroquinone is an aromatic organic compound with the chemical formula C6H4(OH)2, also known as benzene-1,4-diol or quinol, which is a kind of phenol and also a derivative of benzene.

Hydroquinone contains two hydroxyl groups bonded in a para position to the benzene ring.
Hydroquinone is a granular white solid.
Hydroquinone has several applications, which are primarily associated with its function as a reducing agent that is soluble in water.
Hydroquinone is a major component of most black and white photographers for film and paper where, with the compound metol, it transforms silver halides into elemental silver.
Formula of hydroquinone is C6H6O2.

The Molecular Weight is 110.11 g/mol.
The Boiling Point of hydroquinone is 287°C
Also, the Melting Point of hydroquinone is 172°C.
The Density of hydroquinone is 1.3gcm−3.
Hydroquinone is soluble in water.

Hydroquinone has a white-solid appearance.
Industrial production of hydroquinone usually happens in two ways.
The most commonly used technique is identical to the cumene process in the reaction mechanism and, it includes the dialkylation of benzene with propene to produce 1,4diisopropyl benzene.
The compound reacts with air to form bishydroperoxide, which has a similar structure compared to cumene hydroperoxide and, it rearranges in acid to form acetone and hydroquinone.Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles.
Hydroquinone can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.



APPLICATIONS:

-As a reducing agent.
-For the preventive measures of methyl methacrylate.
-In skin whitening.
-Helpful as a biomarker for benzene exposure.
-By photographic developers
-In the treatment of acne scars
-In various cosmetic products



APPLICATIONS:

-Hydroquinone has several applications, which are primarily associated with its function as a reducing agent that is soluble in water.
-Hydroquinone is a major component of most black and white photographers for film and paper where, with the compound metol, it transforms silver halides into elemental silver.
-There are several other applications for its reducing power.
-As a polymerization barrier, hydroquinone inhibits the polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers vulnerable to radical-initiated polymerization by using its antioxidant properties.
-By serving as a free-radical scavenger, hydroquinone helps in improving the shelflife of light-sensitive resins such as preceramic polymers.
-Hydroquinone can form a diphenolate ion by losing a hydrogen cation from both hydroxyl groups.



USAGE:

Hydroquinone has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.
There are various other uses associated with its reducing power.

As a polymerisation inhibitor, exploiting its antioxidant properties, hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.
By acting as a free radical scavenger, hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.
The disodium diphenolate salt of hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.


-Skin depigmentation:

Hydroquinone is used as a topical application in skin whitening to reduce the color of skin.
Hydroquinone does not have the same predisposition to cause dermatitis as metol does.
This is a prescription-only ingredient in some countries.
In 2006, the United States Food and Drug Administration revoked its previous approval of hydroquinone and proposed a ban on all over-the-counter preparations.
The FDA officially banned hydroquinone in 2020 as part of a larger reform of the over-the-counter drug review process.

The FDA stated that hydroquinone cannot be ruled out as a potential carcinogen.
This conclusion was reached based on the extent of absorption in humans and the incidence of neoplasms in rats in several studies where adult rats were found to have increased rates of tumours, including thyroid follicular cell hyperplasias, anisokaryosis (variation in nuclei sizes), mononuclear cell leukemia, hepatocellular adenomas and renal tubule cell adenomas.
The Campaign for Safe Cosmetics has also highlighted concerns.

Numerous studies have revealed that hydroquinone, if taken orally, can cause exogenous ochronosis, a disfiguring disease in which blue-black pigments are deposited onto the skin; however, skin preparations containing the ingredient are administered topically.
The FDA had classified hydroquinone in 1982 as a safe product - generally recognized as safe and effective (GRASE), however additional studies under the National Toxicology Program (NTP) were suggested in order to determine whether there is a risk to humans from the use of hydroquinone.
NTP evaluation showed some evidence of long-term carcinogenic and genotoxic effects.

While hydroquinone remains widely prescribed for treatment of hyperpigmentation, questions raised about its safety profile by regulatory agencies in the EU, Japan, and USA encourage the search for other agents with comparable efficacy.
Several such agents are already available or under research, including azelaic acid, kojic acid, retinoids, cysteamine, topical steroids, glycolic acid, and other substances.
One of these, 4-butylresorcinol, has been proven to be more effective at treating melanin-related skin disorders by a wide margin, as well as safe enough to be made available over the counter.

Hydroquinone is a chemical that a person can use to lighten their skin tone.
Hydroquinone is available as a cream, gel, lotion, or emulsion.
Hydroquinone is generally safe to use, but some people may experience side effects, such as dry skin.
Hydroquinone is a chemical that bleaches the skin.
Hydroquinone can come as a cream, emulsion, gel, or lotion.



PRODUCTION:

Hydroquinone is produced industrially in two main ways.
The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene. Hydroquinone reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.
A second route involves hydroxylation of phenol over a catalyst.

Other, less common methods include:

-A potentially significant synthesis of hydroquinone from acetylene and iron pentacarbonyl has been proposed Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.
-Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.
-Hydroquinone and its derivatives can also be prepared by oxidation of various phenols.
-Examples include Elbs persulfate oxidation and Dakin oxidation.
-Hydroquinone was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.



MECHANISM OF ACTION:

Hydroquinone lightens epidermal, but not dermal, pigmentation by reducing the production of new melanin:

-Reversible inhibition of tyrosinase, an enzyme involved in converting L3,4-diphenylalanine to the skin pigment melanin
-Selective damage to melanocytes and melanosomes.



HOW TO USE IT:

Hydroquinone is applied topically just to the hyperpigmented skin only, twice daily for 3 months, after which time many patients maintain their improvement by using it twice each week.
If there has been no benefit after 3 months of treatment, then the hydroquinone should be stopped.
Management of the underlying cause of the hyperpigmentation is also recommended.

When initiating hydroquinone treatment, Hydroquinone is advisable to:

-Start with a test area about 1 cm in diameter.
-If there is no irritation or redness within 24 hours, the cream can be used more widely on the affected areas.
-Apply a thin film initially daily and if there is no irritation after one week, the application frequency can be increased to twice a day.
-Do not apply close to the eyes or mouth.
-Do not use any other topical medication, particularly benzoyl peroxide.
-Wait for 10 minutes before applying sunscreen or cosmetics over the hydroquinone.
-Treatment should be discontinued if undue redness, scaling, itch, or weeping occurs.



CHEMICAL PROPERTIES:

-Melting point: 172-175 °C(lit.)
-Boiling point: 285 °C(lit.)
-density: 1.32
-vapor density: 3.81 (vs air)
-vapor pressure: 1 mm Hg ( 132 °C)
-refractive index: 1.6320
-Fp: 165 °C
-storage temp.: Store below +30°C.
-solubility: H2O: 50 mg/mL, clear
-pka: 10.35(at 20℃)
-form: Needle-Like Crystals or Crystalline Powder
-color: White to off-white
-Odor: odorless
-Water Solubility: 70 g/L (20 ºC)
-Sensitive: Air & Light Sensitive




BENEFITS:

Hydroquinone is particularly effective for the treatment of postinflammatory hyperpigmentation which is unlikely to recur provided the underlying inflammatory dermatosis is also controlled.
In melasma, 70% of sufferers notice clearance or reduction in pigmentation with twice daily hydroquinone used for three months.
This improvement can be maintained in 50% of individuals with twice weekly application.


NATURAL OCCURRENCES:

Hydroquinones are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide, which collect in a reservoir.
The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
This chamber is lined with cells that secrete catalases and peroxidases.
When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the hydroquinones into p-quinones.

These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.
Hydroquinone is thought to be the active toxin in Agaricus hondensis mushrooms.
Hydroquinone has been shown to be one of the chemical constituents of the natural product propolis.
Hydroquinone is also one of the chemical compounds found in castoreum. This compound is gathered from the beaver's castor sacs.



USES:

-raw material
-intermediate or auxiliaries
-widely used in dye
-rubber
-photograph
-pesticides
-cosmetics
-pharmaceuticals industries



PROPERTIES:

-CAS No.:123-31-9
-Molecular formula:C6H6O2
-Molecular weight:110.12
-Appearance:White or off-white crystal
-Solubility:Easily soluble in hot water, soluble in cool water, ethanol and diethyl ether, slightly soluble in benzene
-Density:1.32g/cm3
-Flash point:141.6℃



REACTIONS:

The reactivity of hydroquinone's hydroxyl groups resembles that of other phenols, being weakly acidic.
The resulting conjugate base undergoes easy O-alkylation to give mono- and diethers.
Similarly, hydroquinone is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation.
This reaction is exploited en route to popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).
The useful dye quinizarin is produced by diacylation of hydroquinone with phthalic anhydride.


-Redox:

Hydroquinone undergoes oxidation under mild conditions to give benzoquinone.
This process can be reversed.
Some naturally occurring hydroquinone derivatives exhibit this sort of reactivity, one example being coenzyme Q.
Industrially this reaction is exploited both with hydroquinone itself but more often with its derivatives where one OH has been replaced by an amine.

When colorless hydroquinone and benzoquinone, a bright yellow solid, are cocrystallized in a 1:1 ratio, a dark-green crystalline charge-transfer complex (melting point 171 °C) called quinhydrone (C6H6O2·C6H4O2) is formed.
This complex dissolves in hot water, where the two molecules dissociate in solution.



PHYSICAL AND CHEMICAL PROPERTIES:

-Boiling point: 287 °C (1013 hPa)
-Density: 1.332 g/cm3 (15 °C)
-Flash point: 165 °C
-Ignition temperature: 515 °C
-Melting Point: 171 °C (decomposition)
-pH value: 3.7 (70 g/l, H₂O)
-Vapor pressure: 1 hPa (132 °C)
-Bulk density: 600 kg/m3
-Solubility: 70 g/l



PROPERTIES:

-CAS number: 123-31-9
-EC index number: 604-005-00-4
-EC number: 204-617-8
-Hill Formula: C₆H₆O₂
-Chemical formula: C₆H₄(OH)₂
-Molar Mass: 110.11 g/mol



SPECIFICATIONS:

-Molecular Weight: 110.11 g/mol
-XLogP3: 0.6
-Hydrogen Bond Donor Count: 2
-Hydrogen Bond Acceptor Count: 2
-Rotatable Bond Count: 0
-Exact Mass: 110.036779430 g/mol
-Monoisotopic Mass: 110.036779430 g/mol
-Topological Polar Surface Area: 40.5Ų
-Heavy Atom Count: 8
-Complexity: 54.9
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes



STORAGE:

Stored in a cool, dry, ventilated place with sealed packing, abstaining from moistness and away from oxidizing agents, alkalis



SYNONYM:

hydroquinone
Benzene-1,4-diol
123-31-9
1,4-benzenediol
Quinol
1,4-Dihydroxybenzene
p-Benzenediol
p-Hydroquinone
p-Hydroxyphenol
4-Hydroxyphenol
p-Dihydroxybenzene
Benzoquinol
Eldoquin
hydroquinol
Eldopaque
Phiaquin
p-Dioxybenzene
Solaquin forte
Dihydroquinone
Hydroquinole
Idrochinone
Tecquinol
Benzohydroquinone
Hidroquinone
Arctuvin
Tequinol
Dihydroxybenzene
Eldopaque Forte
Eldoquin Forte
Derma-Blanch
Hydrochinon
Tenox HQ
Diak 5
Benzene, p-dihydroxy-
Hydrochinone
1,4-Dihydroxy-benzol
Artra
Usaf ek-356
1,4-Diidrobenzene
p-Dioxobenzene
1,4-Dihydroxybenzen
para-Dioxybenzene
para-Hydroquinone
NCI-C55834
Pyrogentistic acid
Black and White Bleaching Cream
1,4-Dihydroxy-benzeen
para-Dihydroxybenzene
beta-quinol
HE 5
Epiquin
Sunvanish
Idrochinone [Italian]
p-Dihydroquinone
alpha-hydroquinone
para-Hydroxyphenol
CHEBI:17594
NSC 9247
Hydrochinon [Czech, Polish]
CCRIS 714
1,4-Dihydroxybenzen [Czech]
1,4-Diidrobenzene [Italian]
quinnone
Eldopacque
HSDB 577
DTXSID7020716
p-Phenylenediol
1,4-Dihydroxy-benzeen [Dutch]
1,4-Dihydroxy-benzol [German]
p Benzendiol
p-Quinol
AI3-00072
CHEMBL537
UNII-XV74C1N1AE
NSC-9247
1,4-Benzoquinol
EINECS 204-617-8
XV74C1N1AE
UN2662
1,4-Hydroxybenzene
Hydroquinone [USP]
MFCD00002339
HQ
BQ(H)
DTXCID70716
Black & White Bleaching Cream
NSC9247
EC 204-617-8
Hydroquinone [UN2662] [Poison]
1,4-Dihydroxybenzene (ring-d4)
Hydroquinone (USP)
TRI-LUMA COMPONENT HYDROQUINONE
NCGC00015523-02
HYDROQUINONE COMPONENT OF TRI-LUMA
HYDROQUINONE (IARC)
HYDROQUINONE [IARC]
HYDROQUINONE (MART.)
HYDROQUINONE [MART.]
HYDROQUINONE (USP-RS)
HYDROQUINONE [USP-RS]
HYDROQUINONE (USP MONOGRAPH)
HYDROQUINONE [USP MONOGRAPH]
CAS-123-31-9
SMR000059154
SR-01000075920
BUTYLHYDROXYANISOLE IMPURITY A (EP IMPURITY)
BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY]
4-DIHYDROXYBENZENE
hydrokinone
hydroquinon
Hidroquinona
Hydrokinon
Hydroquinoue
Accutin
Elopaque
hydroq uinone
hydroquinone gr
p-fenilenediol
p-hidroquinona
p-hidroxifenol
Reduced quinone
a-Hydroquinone
p-Dioxibenceno
4-hidroxifenol
p-Diphenol
p-Hydroxybenzene
b-Quinol
4-Benzenediol
Dihydroxybenzen e
14-Benzoquinol
p-Dihidroxibenceno
Hydroquinone, HQ
.beta.-Quinol
1,4 benzenediol
1,4-Bencenodiol
Hydroquinone,(S)
p-dihydroxy benzene
p -Dihydroxybenzene
PLQ
1,4-Benzendil
Artra (Salt/Mix)
HYDROP
.alpha.-Hydroquinone
1 4-p-Benzenediol
Hydroquinone (8CI)
phenol derivative, 4
1 4-Dihydroxybenzene
1,4-Dihidroxibenceno
4-hydroxyphenyl alcohol
Spectrum_001757
4e3h
HDQ (CHRIS Code)
PYROGENTISIC ACID
SpecPlus_000769
1,4-Dihydrobenzoquinone
ELDOQUIN (TN)
HYDROQUINONE BAKER
hydroquinone for synthesis
Spectrum2_001672
Spectrum3_000656
Spectrum4_000633
Spectrum5_001430
HYDROQUINONE [MI]
Lopac-H-9003
WLN: QR DQ
bmse000293
D03UOT
D08LQA
Epitope ID:116206
HYDROQUINONE [HSDB]
HYDROQUINONE [INCI]
HYDROQUINONE [VANDF]
1,4-Dihydroxybenzene Quinol
Lopac0_000577
SCHEMBL15516
BSPBio_002291
KBioGR_001246
KBioSS_002237
1,4-Dihydroxybenzene, XIII
MLS000069815
MLS001074911
BIDD:ER0340
DivK1c_006865
HYDROQUINONE [WHO-DD]
Hydroquinone, LR, >=99%
SPECTRUM1504237
Hydrochinon(CZECH, POLISH)
SPBio_001883
BDBM26190
Hydroquinone, puriss., 99.0%
KBio1_001809
KBio2_002237
KBio2_004805
KBio2_007373
KBio3_001511
Benzene-1,4-diol (Hydroquinone)
BENZENE, 1,4-DIHYDROXY-
HMS1922H15
HMS2093E08
HMS3261D16
HYDROQUINONE [ORANGE BOOK]
LS-23
Pharmakon1600-01504237
HY-B0951
Hydroquinone [UN2662] [Poison]
Tox21_110169
Tox21_202345
Tox21_300015
Tox21_500577
CCG-39082
NA2662
NSC758707
s4580
STK397446
UN3435
AKOS000119003
Tox21_110169_1
AM10548
DB09526
LP00577
NSC-758707
SDCCGSBI-0050559.P003
UN 2662
Hydroquinone, ReagentPlus(R), >=99%
Hydroquinone, USP, 99.0-100.5%
NCGC00015523-01
NCGC00015523-03
NCGC00015523-04
NCGC00015523-05
NCGC00015523-06
NCGC00015523-07
NCGC00015523-08
NCGC00015523-09
NCGC00015523-10
NCGC00015523-11
NCGC00015523-12
NCGC00015523-13
NCGC00015523-19
NCGC00090880-01
NCGC00090880-02
NCGC00090880-03
NCGC00090880-04
NCGC00090880-05
NCGC00254037-01
NCGC00259894-01
NCGC00261262-01
BP-21160
Hydroquinone, ReagentPlus(R), >=99.5%
SBI-0050559.P002
Hydroquinone, SAJ first grade, >=99.0%
EU-0100577
FT-0606877
H0186
Hydroquinone, SAJ special grade, >=99.0%
EN300-18053
Hydroquinone, meets USP testing specifications
C00530
D00073
H 9003
AB00053361_08
Quinol; 1,4-Benzenediol; 1,4-Dihydroxybenzene
Q419164
J-004910
J-521469
SR-01000075920-1
SR-01000075920-4
Q27102742
Z57127551
094CADDB-59BF-4EDF-B278-59791B203EA2
F1908-0167



IUPAC NAME:

1,4-Benzenediol
1,4-Benzenediol, 1,4-Dihydroxybenzene, HQ, Quinol
1,4-Benzodiol
1,4-Dihydroxybenzene
1,4-dihydroxybenzene
1,4-dihydroxybenzene; hydroquinone; quinol
1,4-dyhydroxybenzene; hydroquinone, quinol
benzene, 1,4-dihydroxy
Benzene-1,4-diol
benzene-1,4-diol
Benzene-4,1-diol
hydoquinone
Hydrochinon
HYDROQUINONE
Hydroquinone
hydroquinone
Hydroquinone
hydroquinone
hydroquinone
quinol




HYDROQUINONE

Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone is a white granular solid.


CAS Number: 123-31-9
EC Number: 204-617-8
MDL number: MFCD00002339
Molecular Formula: C6H6O2 / C6H4-1,4-(OH)2


Hydroquinone is a chemical that a person can use to lighten their skin tone.
Hydroquinone is available as a cream, gel, lotion, or emulsion.
Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.


Hydroquinone is a white granular solid.
Hydroquinone is a white granular solid at room temperature and pressure.
Hydroquinone is generally safe to use, but some people may experience side effects, such as dry skin


Hydroquinone in some countries, including the member states of the European Union under Directives 76/768/EEC:1976.
Hydroquinone is a chemical that bleaches the skin.
Hydroquinone's chemical structure has two hydroxyl groups bonded to a benzene ring in a para position.


Hydroquinone is a white granular solid at room temperature and pressure.
Some biochemical compounds in nature have this sort of Hydroquinone or quinone section in their structures, such as Coenzyme Q, and can undergo similar redox interconversions.


The hydroxyl groups of Hydroquinone are quite weakly acidic.
Hydroquinone can come as a cream, emulsion, gel, or lotion.
A person can apply these products directly to the skin.


Creams that contain Hydroquinone are available with a prescription from a doctor.
Hydroquinone is colourless, crystalline organic compound formed by chemical reduction of benzoquinone.
Hydroquinone is an aromatic organic compound that is a type of phenol, having the chemical formula C6H4(OH)2.


Hydroquinone comprising benzene core carrying two hydroxy substituents para to each other.
Hydroquinone, also known as Hydroquinone or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.


Substituted derivatives of this parent compound are also referred to as hydroquinone.
Hydroquinone has a variety of uses principally associated with its action as a reducing agent which is soluble in water.
People may use hydroquinone as a form of treatment for hyperpigmentation skin conditions, wherein some areas of skin grow darker than surrounding areas.


Hydroquinone or quinol, is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2.
Hydroquinone, also known as Hydroquinone or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.


Hydroquinone bleaches the skin, which can be helpful when treating different forms of hyperpigmentation.
Hydroquinone is a skin-lightening agent.
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.


Hydroquinone belongs to the class of organic compounds known as hydroquinone.
Hydroquinone are compounds containing a hydroquinone moiety, which consists of a benzene ring with a hydroxyl groups at positions 1 and 4.
Hydroquinone can lose an H+ from one of the hydroxyls to form a monophenolate ion or lose an H+ from both to form a diphenolate ion.


Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone is the name recommended for Hydroquinone by the International Union of Pure and Applied Chemistry (IUPAC) in its 1993 Recommendations for the Nomenclature of Organic Chemistry.


Hydroquinone can undergo mild oxidation to convert to the compound parabenzoquinone, C6H4O2, often called p-quinone or simply quinone.
Hydroquinone is an aromatic organic compound which is a type of phenol.
Hydroquinone can be considered a simple polyphenol.


Substituted derivatives of Hydroquinone are also referred to as hydroquinones.
Hydroquinone is a white crystalline solid, C6H4(OH)2; r.d. 1.33; m.p. 170°C; b.p. 285°C.
Hydroquinone is a white granular solid.


Substituted derivatives of this parent compound are also referred to as hydroquinone.
Hydroquinone is a benzenediol.
Hydroquinone, also known as Hydroquinone, is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2.


The name "hydroquinone" was coined by Friedrich Wöhler in 1843.
Hydroquinone appears as light colored crystals or solutions.
Hydroquinone has a variety of uses principally associated with its action as a reducing agent that is soluble in water.


Hydroquinone is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.
Hydroquinone is a major component in most photographic developers where, with the compound Metol, Hydroquinone reduces silver halides to elemental silver.


Substituted derivatives of Hydroquinone are also referred to as hydroquinones.
Hydroquinone is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Hydroquinone is a topical skin-bleaching agent used in the cosmetic treatment of hyperpigmented skin conditions.


The effect of skin lightening caused by hydroquinone is reversible when exposed to sunlight and therefore requires regular use until desired results are achieved.
Various preparations are available including creams, emulsions, gels, lotions and solutions.


The hydroxyl groups of Hydroquinone are quite weakly acidic.
Hydroquinone can lose an H+ from one of the hydroxyls to form a monophenolate ion or lose an H+ from both to form a diphenolate ion.
Reduction of quinone reverses this reaction back to Hydroquinone.
Hydroquinone's chemical structure has two hydroxyl groups bonded to a benzene ring in a para position.


Hydroquinone is available over the counter in a 2% cream and can be prescribed by your dermatologist in higher concentrations.
Hydroquinone has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone is a white granular solid.



USES and APPLICATIONS of HYDROQUINONE:
There are various other uses associated with Hydroquinone's reducing power.
Hydroquinone can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.
Hydroquinone is used as a topical application in skin whitening to reduce the color of skin.


Hydroquinone is used as a topical treatment for skin hyperpigmentation and in various cosmetic products.
As a polymerisation inhibitor, exploiting its antioxidant properties, Hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.


Hydroquinone is also used as a raw material of herbicides, rubber antioxidants and dye stuffs.
Hydroquinone is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles.


By acting as a free radical scavenger, Hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
In human medicine, Hydroquinone is used as a topical application in skin whitening to reduce the color of skin as Hydroquinone does not have the same predisposition to cause dermatitis as metal does.


Hydroquinone can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.
The disodium diphenolate salt of hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.
As a polymerisation inhibitor, exploiting its antioxidant properties, Hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.


Hydroquinone is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.
The disodium diphenolate salt of Hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.


This medicine works by blocking the process in the skin that leads to discoloration.
In the field of water treatment, Hydroquinone is added to the hot water and cooling water of the closed-circuit heating and cooling system, and the corrosion inhibition of the water side Metal energy is carried out.


Hydroquinone is used as raw material, intermediate or auxiliaries, and widely used in dye, rubber, photograph, pesticides, pharmaceuticals industries etc.
Hydroquinone has role skin lightening agent.
Hydroquinone is used in making dyes.


Hydroquinone is also used as a raw material of herbicides, rubber antioxidants and dye stuffs.
Hydroquinone cream is the standard depigmentation or skin-lightening agent.
Hydroquinone is a major component in most photographic developers where, with the compound Metol, Hydroquinone reduces silver halides to elemental silver.


Clinically Hydroquinone is used to treat areas of dyschromia, such as in melasma, chloasma, solar lentigines, freckles, and post-inflammatory hyperpigmentation.
Hydroquinone has a variety of uses principally associated with its action as a reducing agent that is soluble in water.


This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, and monitoring of hydroquinone, so providers can direct patient therapy to optimal outcomes in conditions where it is indicated.
Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin.


Popularized by its usage as a photo-developer, hydroquinone can be used in any condition causing hyperpigmentation.
Hydroquinone is a white crystalline phenol, Hydroquinone, is used as an antioxidant, photographic developer, stabilizer, and reagent.
Common conditions include melasma, freckles, lentigines, age spots and acne scars.


Hydroquinone has a variety of uses principally associated with Hydroquinone's action as a reducing agent which is soluble in water.
Skin sensitivity to hydroquinone may be determined before treatment by applying a small amount of cream to the hyperpigmented area and noting any redness or itching.


If no reaction occurs, initiate treatment.
The disodium diphenolate salt of Hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.
As a general rule, always ensure the area is clean and dry then apply a thin film to the lesion and rub Hydroquinone into the skin well.


Hydroquinone has a variety of uses principally associated with its action as a reducing agent which is soluble in water.
Hands should be washed after the application to avoid unwanted lightening of the fingers.
As a polymerization inhibitor, Hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, etc.


To maintain the desired affect, hydroquinone should be used concurrently with a strong sunscreen.
Hydroquinone is a white crystalline compound, C6H6O2, formed by the reduction of quinone, used chiefly in photography and to inhibit autoxidation reactions.
Many preparations are available as a combination product.


Hydroquinone is commonly used as a biomarker for benzene exposure.
Hydroquinone is a depigmenting agent used to lighten areas of darkened skin such as freckles, age spots, chloasma, and melisma caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.


Hydroquinone is a white crystalline soluble phenol used as a photographic developer.
Hydroquinone decreases the formation of melanin in the skin.
Melanin is the pigment in skin that gives it a brown color.


Hydroquinone is used as an OTC topical lightening agent for disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots and freckles.
Hydroquinone is frequently found in skin-lightening products like bleaching creams.


Hydroquinone can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.
Hydroquinone works by limiting your production of melanin, the hormone that darkens your skin.


Hydroquinone has role antioxidant.
Hydroquinone has role cofactor.
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.


While some people use it to lighten their darker skin, Hydroquinone creams are most commonly used to lighten small, dark patches like sunspots or hyperpigmentation.
Hydroquinone is a major component of most photographic developers where, with the compound Metol, it reduces silver halides to elemental silver.


Creams with Hydroquinone as an ingredient are an excellent non-surgical aesthetic procedure to help you achieve the skin you have always wanted.
Hydroquinoneis a major component in most black and white photographic developers for film and paper where, with the compound metol, Hydroquinone reduces silver halides to elemental silver.


By acting as a free radical scavenger, Hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
The disodium diphenolate salt of Hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.
Unlike skin-lightening surgery, Hydroquinone creams are a cosmetic procedure that can be undertaken in the comfort of your own home after the initial consultation with your dermatologist.


Hydroquinone has role Escherichia coli metabolite.
Hydroquinone has role human xenobiotic metabolites.
Hydroquinone is used as an oxygen scavenger for boiler water, and Hydroquinone is added thereto to remove residual dissolved oxygen when the boiler water is preheated for oxygen removal.


If you have dark patches or old sunspots, creams with Hydroquinone can lighten them and – when combined with other suitable skincare ingredients – can help your skin recover from sun damage.
Hydroquinone is produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils
Hydroquinone is used in photographic processing.


-Melasma:
People with melasma have brown or gray-brown patches on their skin.
These patches tend to develop on the face, such as the cheeks or nose.
They can also appear on areas of skin with high sun exposure, such as the forearms and neck.


-Freckles:
Freckles are darker spots or patches that usually occur in fair skin.
They can become more noticeable with exposure to sunlight.


-Lentigines:
Lentigines, or age spots, develop on areas of skin with the highest sun exposure.
For example, they can appear on the face or the backs of the hands.
They tend to be flat, dark, and between 0.2 centimeters (cm) and 2 cm in width.


-Acne scars:
Excess oil, dead skin cells, and bacteria can build up in skin pores and cause acne.
The body tries to repair the damage, but sometimes, it leaves scars.


-Other uses:
Some people may want to lighten their skin for cosmetic reasons.
This can have benefits for confidence and self-esteem.
However, it is important to note that the above conditions are all harmless.



PRODUCTION OF
Hydroquinone is produced industrially in two main ways.
The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene. This compound reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.

A second route involves hydroxylation of phenol over a catalyst.
The conversion uses hydrogen peroxide and affords a mixture of hydroquinone and its ortho isomer catechol (benzene-1,2-diol):
C6H5OH+H2O2⟶C6H4(OH)2+H2

A potentially significant synthesis of hydroquinone from acetylene and iron pentacarbonyl has been proposed.
Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.
Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.

Hydroquinone and its derivatives can also be prepared by oxidation of various phenols.
Examples include Elbs persulfate oxidation and Dakin oxidation.
Hydroquinone was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.



REACTIONS OF
The reactivity of hydroquinone's hydroxyl groups resembles that of other phenols, being weakly acidic.
The resulting conjugate base undergoes easy O-alkylation to give mono- and diethers.
Similarly, hydroquinone is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation.
This reaction is exploited en route to popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).
The useful dye quinizarin is produced by diacylation of hydroquinone with phthalic anhydride.



PRODUCTION of HYDROQUINONE:
Hydroquinone is produced industrially by two main routes.

*The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene.
This compound reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.

*A second route involves hydroxylation of phenol over a catalyst.
The conversion uses hydrogen peroxide and affords a mixture of hydroquinone and its ortho isomer catechol (benzene-1,2-diol):
C6H5OH + H2O2 → C6H4(OH)2 + H2O

Other, less common methods include:
A potentially significant synthesis of hydroquinone from acetylene and iron pentacarbonyl has been proposed Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.

Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.
Hydroquinone and its derivatives can also be prepared by oxidation of various phenols.

Examples include Elbs persulfate oxidation and Dakin oxidation.
Hydroquinone was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.
Aniline is oxidized to p-benzoquinone with manganese dioxide in sulfuric acid medium and then reduced to hydroquinone with iron powder.



REDOX:
Hydroquinone undergoes oxidation under mild conditions to give benzoquinone.
This process can be reversed.
Some naturally occurring hydroquinone derivatives exhibit this sort of reactivity, one example being coenzyme Q.
Industrially this reaction is exploited both with hydroquinone itself but more often with its derivatives where one OH has been replaced by an amine.

When colorless Hydroquinone and benzoquinone, a bright yellow solid, are cocrystallized in a 1:1 ratio, a dark-green crystalline charge-transfer complex (melting point 171 °C) called quinhydrone (C6H6O2·C6H4O2) is formed.
This complex dissolves in hot water, where the two molecules dissociate in solution.



CATEGORIES of HYDROQUINONE:
*Antioxidants
*Benzene Derivatives
*Compounds used in a research, industrial, or household setting
*Depigmenting Agents
*Dermatologicals
*Melanin Synthesis Inhibitor
*Melanin Synthesis Inhibitors
*Mutagens
*Noxae
*Phenols
*Protective Agents
*Radiation-Protective Agents



HOW DOES HYDROQUINONE WORK?
Hydroquinone bleaches your skin by decreasing the number of melanocytes present.
Melanocytes make melanin, which is what produces your skin tone.
In cases of hyperpigmentation, more melanin is present due to an increase in melanocyte production.
By controlling these melanocytes, your skin will become more evenly toned over time.
It takes about four weeks on average for the ingredient to take effect.
It may take several months of consistent use before you see full results.



EXTERNAL DESCRIPTORS of HYDROQUINONE:
*Hydroquinones
*Benzenediol
*An electron-transfer-related quinol
*A benzenediol



REACTIONS of HYDROQUINONE:
The reactivity of Hydroquinone's hydroxyl groups resembles that of other phenols, being weakly acidic.
The resulting conjugate base undergoes easy O-alkylation to give mono- and diethers.

Similarly, hydroquinone is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation.
This reaction is exploited en route to popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).
The useful dye quinizarin is produced by diacylation of hydroquinone with phthalic anhydride.



AMINATION OF HYDROQUINONE:
An important reaction is the conversion of hydroquinone to the mono- and diamine derivatives.
Methylaminophenol, used in photography, is produced in this way:

C6H4(OH)2+CH3NH2methylamine⟶HOC6H4NHCH3+H2O
Diamines, useful in the rubber industry as antiozone agents, are similarly produced from aniline:
C6H4(OH)2+2C6H5NH2 aniline⟶C6H4(N(H)6H5)2+2H2O



SKIN DEPIGMENTATION OF HYDROQUINONE:
Hydroquinone is used as a topical application in skin whitening to reduce the color of skin.
Hydroquinone does not have the same predisposition to cause dermatitis as metol does.
This is a prescription-only ingredient in some countries, including the member states of the European Union under Directives 76/768/EEC:1976.



REDOX of HYDROQUINONE:
Hydroquinone undergoes oxidation under mild conditions to give benzoquinone.
This process can be reversed.
Some naturally occurring hydroquinone derivatives exhibit this sort of reactivity, one example being coenzyme Q.
Industrially this reaction is exploited both with hydroquinone itself but more often with its derivatives where one OH has been replaced by an amine.

When colorless hydroquinone and benzoquinone, a bright yellow solid, are cocrystallized in a 1:1 ratio, a dark-green crystalline charge-transfer complex (melting point 171 °C) called quinhydrone (C6H6O2•C6H4O2) is formed.
This complex dissolves in hot water, where the two molecules dissociate in solution.



NATURAL OCCURRENCES OF HYDROQUINONE:
Hydroquinones are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.
The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.

This chamber is lined with cells that secrete catalases and peroxidases.
When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the hydroquinones into p-quinones.
These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.

Hydroquinone has been shown to be one of the chemical constituents of the natural product propolis.
It is also one of the chemical compounds found in castoreum.
This compound is gathered from the beaver's castor sacs.



AMINATION of HYDROQUINONE:
An important reaction is the conversion of Hydroquinone to the mono- and diamine derivatives.
Methylaminophenol, used in photography, is produced in this way:
C6H4(OH)2 + CH3NH2 → HOC6H4NHCH3 + H2O

Diamines, useful in the rubber industry as antiozone agents, are similarly produced from aniline:
C6H4(OH)2 + 2 C6H5NH2 → C6H4(N(H)C6H5)2 + 2 H2O



HOW TO USE HYDROQUINONE CREAM:
Follow all directions on the product package, or use as directed by your doctor.
Before using, apply a small amount of this medicine to an area of unbroken skin, and check the area within 24 hours for any serious side effects.
If the test area is itching, red, puffy, or blistering, do not use this product and contact your doctor.
If there is just mild redness, then treatment with this product may begin.

Apply this medication to the affected areas of skin, usually twice daily or as directed by your doctor.
This medication is for use on the skin only.
If it is used incorrectly, unwanted skin lightening may occur.
If you do get this medication in those areas, flush with plenty of water.

This medication may make the treated areas of skin more sensitive to the sun.
Use a sunscreen and wear protective clothing on the treated areas of skin when outdoors.
Use this medication regularly to get the most benefit from it.
To help you remember, use it at the same times each day.



NATURAL OCCURRENCES of HYDROQUINONE:
Hydroquinone are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.
The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.

This chamber is lined with cells that secrete catalases and peroxidases.
When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the Hydroquinones into p-quinones.

These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.
It is also one of the chemical compounds found in castoreum.
This compound is gathered from the beaver's castor sacs.
In bearberry (Arctostaphylos uva-ursi), arbutin is converted to hydroquinone.



MECHANISM OF HYDROQUINONE:
Hydroquinone produces reversible lightening of the skin by interfering with melanin production by the melanocytes.
Specifically, inhibition of the enzymatic conversion of tyrosine to DOPA (dihydroxyphenylalanine) results in the desired chemical reduction of pigment.
Ultimately, this causes a decrease in the number of melanocytes and decreased transfer of melanin leading to lighter skin.



OBJECTIVES OF HYDROQUINONE:
Outline the indications for using hydroquinone therapy.
Describe the mechanism of action of hydroquinone.
Summarize the potential adverse events associated with hydroquinone.
Review interprofessional team strategies for improving care coordination and communication to advance improved outcomes using hydroquinone when indicated.



REACTIONS KNOWN to PRODUCE HYDROQUINONE:
4-aminophenol degradation :
4-aminophenol + H2O + H+ → Hydroquinone + ammonium

4-hydroxyacetophenone degradation :
4-hydroxyphenylacetate + H2O → Hydroquinone + acetate

4-nitrophenol degradation I :
1,4-benzoquinone + NADPH + H+ → Hydroquinone + NADP+

echinenone and zeaxanthin biosynthesis (Synechocystis) :
all-trans-β-carotene + 2 1,4-benzoquinone + H2O → echinenone + 2 Hydroquinone

Not in pathways:
arbutin-6-phosphate + H2O → β-D-glucose 6-phosphate + Hydroquinone
4-hydroxybenzoate + NAD(P)H + oxygen + 2 H+ → CO2 + Hydroquinone + NAD(P)+ + H2O



HOW DOES HYDROQUINONE WORK?
For some people, melanocytes produce excessive amounts of melanin, resulting in dark patches of skin — a condition known as Melasma.
These can appear as grey-brown patches, normally on the cheeks, nose, chin, forehead, and upper lip.
In some cases, dark patches may also appear on the neck and the arms.

Although it’s women who are normally affected by Melasma, Hydroquinone does affect a small number of men too.
Melasma is also very common among pregnant women due to the fluctuation of their hormones.
Sun exposure can also be a common cause of the condition.

Whatever your reasons for considering using creams with hydroquinone, it’s vital you discuss treatment with a trained professional.
The effects are not immediate, and you will need to apply the hydroquinone cream correctly for the time specified by your doctor.
Generally, it takes around four weeks for effects to become noticeable, although some patients may find that it takes longer to see visible results with even the best hydroquinone creams.



HYDROQUINONE in NATURE:
White needle-like crystals.
Soluble in alcohol and ether, soluble in water, slightly soluble in benzene.
Visible light in the air easily turned to light red.

The aqueous solution can be oxidized to Brown in air.
Hydroquinone is a weak acid.
Hydroquinone reacts with most of the oxidizing agents and is converted to O-and p-benzoquinones.
Hydroquinone has a, beta and gamma; Three crystal forms.

Type A is a triangular needle-like or diamond-like crystal, crystallized from water and stable.
Lu is a triangular crystal, crystallized from methanol, unstable.
The & gamma; Type is monoclinic crystal, which is obtained by sublimation method and is unstable.
All three crystals can be rubbed to emit fluorescence.
Hydroquinone is the flash point is high, the vapor pressure is low.



WHAT SKIN CONDITIONS CAN BENEFIT FROM HYDROQUINONE CREAMS?
The most common use of hydroquinone creams is to treat skin conditions that cause hyperpigmentation.
Besides Melasma, these conditions include:
– Acne scars
– Age spots
– Freckles
– Psoriasis and/or eczema marks.

What’s often overlooked by those untrained in the use of hydroquinone is that it can’t treat actively inflamed areas.
Hydroquinone creams can certainly help with old acne scars, for example, but they can’t help if you currently have an active acne breakout that’s causing dark redness.



ALTERNATIVE PARENTS of HYDROQUINONE:
*1-hydroxy-2-unsubstituted benzenoids
*Benzene and substituted derivatives
*Organooxygen compounds
*Hydrocarbon derivatives



SUBSTITUENTS of HYDROQUINONE:
*Hydroquinone
*1-hydroxy-2-unsubstituted benzenoid
*Monocyclic benzene moiety
*Organic oxygen compound
*Hydrocarbon derivative
*Organooxygen compound
*Aromatic homomonocyclic compound



THE REASON FOR THE BOILING POINT of HYDROQUINONE BEING HIGHER THAN THAT OF BENZENE-1,3-DIOL:
Hydroquinone has a boiling point of 287°C and Benzene-1,3-diol has a boiling point of 277°C and Benzene-1,2-diol has a boiling point of 245.5°C.
This could be attributed to the ease of formation of 2 intermolecular hydrogen bonds with the 2 hydroxy groups of these molecules increasing when the hydroxy groups are placed apart, to minimise steric hindrance and repulsion.
Hydroquinone could form intermolecular hydrogen bonds with more stability than Benzene-1,3-diol or Benzene-1,2-diol as these two will get destabilised by steric repulsion when large groups have to reach nearer to form hydrogen bonds.

Thus, the extent of intermolecular hydrogen bonding in :
Hydroquinone > Benzene-1,3-diol > Benzene-1,2-diol
To overcome this attraction, more energy is needed.
Hence the same is the order of their Boiling Points.




PHYSICAL and CHEMICAL PROPERTIES of HYDROQUINONE:
CAS No.:123-31-9
Molecular formula:C6H6O2
Molecular weight:110.12
Appearance:White or off-white crystal
Solubility:Easily soluble in hot water, soluble in cool water, ethanol and diethyl ether, slightly soluble in benzene
Density:1.32g/cm3
Flash point:141.6℃
Molecular Weight: 110.11
Appearance Form: crystalline
Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: 3,7 at 70 g/l
Melting point/freezing point:
Melting point/range: 172 - 175 °C - lit.
Initial boiling point and boiling range: 285 °C - lit.
Flash point: 165 °C at ca.1.013 hPa

Evaporation rate: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 1 hPa at 132 °C
Vapor density: 3,80 - (Air = 1.0)
Density: 1,332 g/cm3 at 15 °C
Relative density: No data available
Water solubility 72 g/l at 25 °C - completely soluble
Partition coefficient: n-octanol/water
log Pow: 0,59 - Bioaccumulation is not expected.
Autoignition temperature: 515,56 °C at 1.013 hPa
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Relative vapor density: 3,80 - (Air = 1.0)

Water Solubility: 95.5 g/L
logP: 0.71
logP: 1.37
logS: -0.06
pKa (Strongest Acidic): 9.68
pKa (Strongest Basic): -5.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 2
Polar Surface Area: 40.46 Ų
Rotatable Bond Count: 0
Refractivity: 30.02 m³·mol⁻¹
Polarizability: 10.75 ų
Number of Rings: 1
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No



FIRST AID MEASURES of HYDROQUINONE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROQUINONE:
-Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROQUINONE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROQUINONE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use safety goggles.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Use protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROQUINONE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
*Hygiene measures:
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROQUINONE:
-Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Hydroquinone
Idrochinone
Quinol
1,4-Dihydroxybenzene
p-dihydroxybenzene
1,4-Hydroxy benzene
1,4-Benzenediol
HQ
1,4-Dihydroxybenzene
Hydroquinone
Quinol
P-Hydroquinone
Hydrochinon
Dihydroquinone
Hydroquinol
Benzoquinol
Hydrochinone
Hidroquinone
Hidroquin
Idrochinone
Para-Hydroquinone
Hydroquinole
Hidroquilaude
1, 4-Dihydroxy-Benzeen
1, 4-Diidrobenzene
Pyrogentistic Acid
Hydroquinoue
Ccris 714
Diak 5
1,4-Benzenediol
1,4-Dihydroxybenzene
4-Hydroxyphenol
Benzene-1,4-diol
Eldoquin
Hydroquinone
hydroquinone
p-Benzenediol
p-Hydroquinone
p-hydroxyphenol
Quinol
1,4-benzenediol
benzene-1,4-diol
p-dihydroxybenzene
1,4-dihydroxybenzene
hydroquinol
p-hydroquinone


HYDROQUINONE (BENZENE-1,4-DIOL)
Hydroquinone (benzene-1,4-diol) is produced by the oxidation of aniline or phenol, by the reduction of quinone, or from a reaction of acetylene and carbon monoxide.
Hydroquinone (benzene-1,4-diol) occurs naturally as a glucose ether, also known as arbutin, in the leaves of many plants and in fruits, as well as one of the agents used in the defense mechanism of the bombardier beetle, family Carabidae.
White needle-like crystals or crystalline powder.

CAS: 123-31-9
MF: C6H6O2
MW: 110.11
EINECS: 204-617-8

Synonyms
Hydroquinone, 99.5%, 99.5%;HYDROXYQUINOL;HYDROCHINONE;HYDROQUINONE;AKOS BBS-00004220;hydroquinone--1,4-benzenediol;Idrochinone;Melanex;hydroquinone;123-31-9;Benzene-1,4-diol;1,4-benzenediol;Quinol;1,4-Dihydroxybenzene;p-Benzenediol;p-Hydroquinone;p-Hydroxyphenol;4-Hydroxyphenol;p-Dihydroxybenzene;Benzoquinol;hydroquinol;Dihydroquinone;Eldoquin;p-Dioxybenzene;Solaquin forte;Eldopaque;Hydroquinole;Idrochinone;Tecquinol;Phiaquin;Benzohydroquinone;Hidroquinone;Arctuvin;Tequinol;Dihydroxybenzene;Eldopaque Forte;Eldoquin Forte;Derma-Blanch;Hydrochinon;Tenox HQ
;Diak 5;Benzene, p-dihydroxy-;Hydrochinone;1,4-Dihydroxy-benzol;Artra;Usaf ek-356;1,4-Diidrobenzene;p-Dioxobenzene;1,4-Dihydroxybenzen;para-Dioxybenzene;para-Hydroquinone;NCI-C55834;Black and White Bleaching Cream;1,4-Dihydroxy-benzeen;para-Dihydroxybenzene;beta-quinol;HE 5;Pyrogentistic acid;Epiquin;Melanex;Sunvanish;Idrochinone [Italian];p-Dihydroquinone;alpha-hydroquinone;CHEBI:17594;NSC 9247;Hydrochinon [Czech, Polish];CCRIS 714;1,4-Dihydroxybenzen [Czech];1,4-Diidrobenzene [Italian];HSDB 577;DTXSID7020716;1,4-Dihydroxy-benzeen [Dutch];1,4-Dihydroxy-benzol [German];AI3-00072;CHEMBL537;UNII-XV74C1N1AE;NSC-9247;EINECS 204-617-8;XV74C1N1AE;UN2662;Hydroquinone (USP);Hydroquinone [USP];MFCD00002339;HQ;DTXCID70716;NSC9247;EC 204-617-8;Hydroquinone [UN2662] [Poison];1,4-Dihydroxybenzene (ring-d4);TRI-LUMA COMPONENT HYDROQUINONE;NCGC00015523-02;HYDROQUINONE COMPONENT OF TRI-LUMA;HYDROQUINONE (IARC);HYDROQUINONE [IARC];para-Hydroxyphenol;Quinol; 1,4-Benzenediol; 1,4-Dihydroxybenzene;HYDROQUINONE (MART.);HYDROQUINONE [MART.];HYDROQUINONE (USP-RS);HYDROQUINONE [USP-RS];quinnone;Eldopacque;p-Phenylenediol;p Benzendiol;HYDROQUINONE (USP MONOGRAPH);HYDROQUINONE [USP MONOGRAPH];p-Quinol;1,4-Benzoquinol;CAS-123-31-9;SMR000059154;1,4-Hydroxybenzene;SR-01000075920;BUTYLHYDROXYANISOLE IMPURITY A (EP IMPURITY);BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY];4-DIHYDROXYBENZENE;hydroquinon;BQ(H)

Hydroquinone (benzene-1,4-diol) interferes with the production of the pigment melanin by epidermal melanocytes through at least two mechanisms: it competitively inhibits tyrosinase, one of the principal enzymes responsible for converting tyrosine to melanin, and it selectively damages melanocytes and melanosomes (the organelles within which melanin is stored).
Hydroquinone (benzene-1,4-diol) is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.
Hydroquinone (benzene-1,4-diol) works by blocking the process in the skin that leads to discoloration.
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone (benzene-1,4-diol) has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone (benzene-1,4-diol) is a white granular solid.
Substituted derivatives of this parent compound are also referred to as hydroquinones.
The name "Hydroquinone (benzene-1,4-diol)" was coined by Friedrich Wöhler in 1843.
In 2021, Hydroquinone (benzene-1,4-diol) was the 282nd most commonly prescribed medication in the United States, with more than 800,000 prescriptions.

Hydroquinone (benzene-1,4-diol) Chemical Properties
Melting point: 172-175 °C(lit.)
Boiling point: 285 °C(lit.)
Density: 1.32
Vapor density: 3.81 (vs air)
Vapor pressure: 1 mm Hg ( 132 °C)
Refractive index: 1.6320
Fp: 165 °C
Storage temp.: Store below +30°C.
Solubility H2O: 50 mg/mL, clear
Pka: 10.35(at 20℃)
Form: Needle-Like Crystals or Crystalline Powder
Color: White to off-white
Odor: odorless
Water Solubility: 70 g/L (20 ºC)
Sensitive: Air & Light Sensitive
Merck: 14,4808
BRN: 605970
Henry's Law Constant: (x 10-9 atm?m3/mol): <2.07 at 20 °C (approximate - calculated from water solubility and vapor pressure)
Exposure limits NIOSH REL: 15-min ceiling 2, IDLH 50; OSHA PEL: TWA 2; ACGIH TLV: TWA 2 (adopted).
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, strong bases, oxygen, ferric salts. Light and air-sensitive. Discolours in air.
InChIKey: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
LogP: 0.59 at 20℃
CAS DataBase Reference: 123-31-9(CAS DataBase Reference)
NIST Chemistry Reference: Hydroquinone (benzene-1,4-diol) (123-31-9)
IARC: 3 (Vol. 15, Sup 7, 71) 1999
EPA Substance Registry System: Hydroquinone (benzene-1,4-diol) (123-31-9)

Hydroquinone (benzene-1,4-diol), a colorless, hexagonal prism, has been reported to be a good antimitotic and tumor-inhibiting agent.
Hydroquinone (benzene-1,4-diol) is a reducing agent used in a photographic developer, which polymerizes in the presence of oxidizing agents.
In the manufacturing industry Hydroquinone (benzene-1,4-diol) may occur include bacteriostatic agent, drug, fur processing, motor fuel, paint, organic chemicals, plastics, stone coating, and styrene monomers.

Uses
Reducing agent prevents polymerization of resin monomers lightens darkened skin, light sensitive.
Use as photographic reducer and developer; as reagent in the determination of small quantities of phosphate; as antioxidant.
Hydroquinone (benzene-1,4-diol) is a pigment-lightening agent used in bleaching creams.
Hydroquinone (benzene-1,4-diol) combines with oxygen very rapidly and becomes brown when exposed to air.
Although Hydroquinone (benzene-1,4-diol) occurs naturally, the synthetic version is the one commonly used in cosmetics.
Application to the skin may cause allergic reaction and increase skin sun sensitivity.
Hydroquinone (benzene-1,4-diol) is potentially carcinogenic and is associated with causing ochronosis, a discoloration of the skin.
The u.S. FDA has banned hydroquinone from oTC cosmetic formulations, but allows 4 percent in prescription products.
Hydroquinone (benzene-1,4-diol)'s use in cosmetics is prohibited in some european countries and in Australia.
Photographic reducer and developer; antioxidant; stabilizing agent for some polymers; intermediate in the manufacturing of some dyes and pigments; in cosmetic formulations.

Hydroquinone (benzene-1,4-diol) has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone (benzene-1,4-diol) is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.
There are various other uses associated with its reducing power.
As a polymerisation inhibitor, exploiting its antioxidant properties, Hydroquinone (benzene-1,4-diol) prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.
By acting as a free radical scavenger, hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone (benzene-1,4-diol) can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.
The disodium diphenolate salt of Hydroquinone (benzene-1,4-diol) is used as an alternating comonomer unit in the production of the polymer PEEK.

Skin depigmentation
Hydroquinone (benzene-1,4-diol) is used as a topical application in skin whitening to reduce the color of skin.
Hydroquinone (benzene-1,4-diol) does not have the same predisposition to cause dermatitis as metol does.
In 2006, the United States Food and Drug Administration revoked its previous approval of Hydroquinone (benzene-1,4-diol) and proposed a ban on all over-the-counter preparations.
The FDA officially banned hydroquinone in 2020 as part of a larger reform of the over-the-counter drug review process.
The FDA stated that Hydroquinone (benzene-1,4-diol) cannot be ruled out as a potential carcinogen.
This conclusion was reached based on the extent of absorption in humans and the incidence of neoplasms in rats in several studies where adult rats were found to have increased rates of tumours, including thyroid follicular cell hyperplasias, anisokaryosis (variation in nuclei sizes), mononuclear cell leukemia, hepatocellular adenomas and renal tubule cell adenomas.
The Campaign for Safe Cosmetics has also highlighted concerns.

Numerous studies have revealed that Hydroquinone (benzene-1,4-diol), if taken orally, can cause exogenous ochronosis, a disfiguring disease in which blue-black pigments are deposited onto the skin; however, skin preparations containing the ingredient are administered topically.
The FDA had classified Hydroquinone (benzene-1,4-diol) in 1982 as a safe product - generally recognized as safe and effective (GRASE), however additional studies under the National Toxicology Program (NTP) were suggested in order to determine whether there is a risk to humans from the use of hydroquinone.
NTP evaluation showed some evidence of long-term carcinogenic and genotoxic effects.

While Hydroquinone (benzene-1,4-diol) remains widely prescribed for treatment of hyperpigmentation, questions raised about its safety profile by regulatory agencies in the EU, Japan, and USA encourage the search for other agents with comparable efficacy.
Several such agents are already available or under research, including azelaic acid, kojic acid, retinoids, cysteamine, topical steroids, glycolic acid, and other substances.
One of these, 4-butylresorcinol, has been proved to be more effective at treating melanin-related skin disorders by a wide margin, as well as safe enough to be made available over the counter.

Clinical Use
Hydroquinone (benzene-1,4-diol) is applied topically to treat disorders characterized by excessive melanin in the epidermis, such as melasma.
In the United States, nonprescription skin-lightening products contain Hydroquinone (benzene-1,4-diol) at concentrations of 2% or less; higher concentrations are available by prescription.

Production Methods
There are three current manufacturing processes for HQ: oxidative cleavage of diisopropylbenzene, oxidation of aniline, and hydroxylation of phenol.
Diisopropylbenzene is air oxidized to the intermediate diisopropylbenzene bishydroperoxide.
This Hydroquinone (benzene-1,4-diol)hydroperoxide is purified by extraction and reacted further to form hydroquinone.
The purified product is isolated by filtration and packaged.
The process can be almost entirely closed, continuous, computer-controlled, and monitored.
Hydroquinone (benzene-1,4-diol) can also be prepared by oxidizing aniline to quinone in the presence of manganese dioxide and sulfuric acid.
p-Benzoquinone is then reduced to HQ using iron oxide.
The resulting hydroquinone is crystallized and dried.
The process occurs in a closed system.
HQis also manufactured by hydroxylation of phenol using hydrogen peroxide as a hydroxylation agent.
The reaction is catalyzed by strong mineral acids or ferrous or cobalt salts.

Manufacturing Process
Into a pressure reactor there was charged 100 ml of methanol and 1 g of diruthenium nonacarbonyl.
The reactor was closed, cooled in solid carbon dioxide/acetone, and evacuated.
Acetylene, to the extent of 1 mol (26 g), was metered into the cold reactor.
Carbon monoxide was then pressured into this vessel at 835-980 atmospheres, during a period of 16.5 hours; while the reactor was maintained at 100°C to 150°C.
The reactor was then cooled to room temperature and opened.
The reaction mixture was removed from the vessel and distilled at a pressure of 30-60 mm, and a bath temperature of 30°C to 50°C until the methanol had all been removed.

The extremely viscous tarry residue remaining in the still pot was given a very crude distillation, the distillate boiling at 82°C to 132°C/2 mm.
In an attempt to purify this distillate by a more careful distillation, 5.3 g of a liquid distilling from 53°C to 150°C/5 mm was collected.
At this point, much solid sublimate was noted not only in this distillate but in the condenser of the still. 7 g of the solid sublimate was scraped out of the condenser of the still.
Recrystallization of the sublimate from ethyl acetate containing a small amount of petroleum ether gave beautiful crystals melting at 175°C to 177°C (5 g).
Infrared analysis confirmed that this compound was hydroquinone (9% conversion).

Reactivity Profile
Hydroquinone (benzene-1,4-diol) is a slight explosion hazard when exposed to heat. Incompatible with strong oxidizing agents.
Also incompatible with bases.
Hydroquinone (benzene-1,4-diol) reacts with oxygen and sodium hydroxide.
Reacts with ferric salts.
Hot and/or concentrated NaOH can cause Hydroquinone (benzene-1,4-diol) to decompose exothermically at elevated temperature.
Exposures to Hydroquinone (benzene-1,4-diol) in large quantities by accidental oral ingestion produce toxicity and poisoning.

The symptoms of poisoning include, but are not limited to, blurred speech, tinnitus, tremors, sense of suffocation, vomiting, muscular twitching, headache, convul- sions, dyspnea and cyanosis from methemoglobinemia, coma, and collapse from respira- tory failure.
Occupational workers should be allowed to work with protective clothing and dust masks with full-face or goggles to protect the eyes, and under proper management.
Hydroquinone is very toxic; the probable oral lethal dose for humans is 50-500 mg/kg, or between 1 teaspoon and 1 ounce for a 150 lb. person.
Hydroquinone (benzene-1,4-diol) is irritating but not corrosive.
Fatal human doses have ranged from 5-12 grams, but 300-500 mg have been ingested daily for 3-5 months without ill effects.
Death is apparently initiated by respiratory failure or anoxia.

Production
Hydroquinone (benzene-1,4-diol) is produced industrially in two main ways.
The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene.
Hydroquinone (benzene-1,4-diol) reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.
Other, less common methods include:

A potentially significant synthesis of hydroquinone from acetylene and iron pentacarbonyl has been proposed.
Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.
Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.
Hydroquinone (benzene-1,4-diol) and its derivatives can also be prepared by oxidation of various phenols, such as aniline and DIPB.
Examples include Elbs persulfate oxidation and Dakin oxidation.
Hydroquinone (benzene-1,4-diol) was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.
Hydrolysis of chlorinated phenol, described as being used in China.
Note that methods such as hydrolysis of chlorinated phenol and oxidation of phenols are much more polluting methods than some others.

Reactions
The reactivity of Hydroquinone (benzene-1,4-diol)'s hydroxyl groups resembles that of other phenols, being weakly acidic.
The resulting conjugate base undergoes easy O-alkylation to give mono- and diethers.
Similarly, Hydroquinone (benzene-1,4-diol) is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation.
This reaction is exploited en route to popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).
The useful dye quinizarin is produced by diacylation of Hydroquinone (benzene-1,4-diol) with phthalic anhydride.

Redox
Hydroquinone (benzene-1,4-diol) undergoes oxidation under mild conditions to give benzoquinone.
This process can be reversed.
Some naturally occurring hydroquinone derivatives exhibit this sort of reactivity, one example being coenzyme Q.
Industrially this reaction is exploited both with Hydroquinone (benzene-1,4-diol) itself but more often with its derivatives where one OH has been replaced by an amine.
When colorless Hydroquinone (benzene-1,4-diol) and benzoquinone, a bright yellow solid, are cocrystallized in a 1:1 ratio, a dark-green crystalline charge-transfer complex (melting point 171 °C) called quinhydrone (C6H6O2·C6H4O2) is formed.
This complex dissolves in hot water, where the two molecules dissociate in solution.
HYDROQUINONE (BENZENE-1,4-DIOL)
Hydroquinone (benzene-1,4-diol) is a Melanin Synthesis Inhibitor.
Hydroquinone (benzene-1,4-diol) is a benzenediol and a member of hydroquinones.


CAS Number: 123-31-9
EC Number: 204-617-8
MDL number: MFCD00002339
Molecular Formula: C6H6O2 / C6H4-1,4-(OH)2 / C6H4(OH)2



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p-dihydroxybenzene, p-hydroxyphenol, 1,4-Hydroxy benzene, Calcium Dobesilate Monohydrate Imp. A (EP), Dobesilate Imp. A (EP), Hydroquinone, 1,4-Benzoquinol, 1,4-Dihydroxybenzene, 1,4-Phenylenediol, 1,4-p-Benzenediol, 4-Hydroxyphenol, Aida, Arctuvin, BQ(H), Benzohydroquinone, Benzoquinol, Black & White Bleaching Cream, Diak 5, Dihydroquinone, Eldopacque, Eldopaque, Eldopaque Forte, Eldoquin, Eldoquin Forte, HE 5, Hydroquinol, NSC 9247, Phiaquin, Quinol, Solaquin Forte, Solution Q, Tecquinol, Tenox HQ, p-Benzenediol, p-Dihydroquinone, p-Dihydroxybenzene, p-Dioxybenzene, p-Hydroquinone, p-Hydroxyphenol, p-Phenylenediol, p-Quin, Calcium Dobesilate Monohydrate Impurity A, Etamsylate Impurity A, Calcium Dobesilate Impurity A, 1,4-Benzenediol, 1,4-Dihydroxybenzene, 4-Hydroxyphenol, Benzene-1,4-diol, Eldoquin, p-Benzenediol, p-Hydroquinone, p-Hydroxyphenol, Quinol, Artra, Eldopaque, Esoterica, Hidroquilaude, Hidroquin, Hidroquinona isdin, Licostrata, Lustra, Melanasa, Melanex, Melpaque, Melquin, Neostrata HQ, Phiaquin, Solaquin, Ultraquin, beta-Quinol, Hydroquinone, copper (1+) salt, Hydroquinone, lead (2+) salt (2:1), Hydroquinone, monocopper (2+) salt, 1,4-Dihydroxy-benzeen, 1,4-Dihydroxy-benzol,
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Hydroquinone (benzene-1,4-diol) appears as light colored crystals or solutions.
Hydroquinone (benzene-1,4-diol) is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Hydroquinone (benzene-1,4-diol) has a role as a cofactor, a carcinogenic agent, an Escherichia coli metabolite, a human xenobiotic metabolite, a skin lightening agent, an antioxidant and a mouse metabolite.


Hydroquinone (benzene-1,4-diol) is a benzenediol and a member of hydroquinones.
Hydroquinone (benzene-1,4-diol) is a metabolite found in or produced by Escherichia coli.
Hydroquinone (benzene-1,4-diol) is a Melanin Synthesis Inhibitor.


The mechanism of action of Hydroquinone (benzene-1,4-diol) is as a Melanin Synthesis Inhibitor.
The physiologic effect of Hydroquinone (benzene-1,4-diol) is by means of Depigmenting Activity.
Hydroquinone (benzene-1,4-diol) is a natural product found in Spiranthes vernalis, Phomopsis velata, and other organisms with data available.


Hydroquinone (benzene-1,4-diol) is an aromatic organic compound which is a type of phenol.
Hydroquinone (benzene-1,4-diol) is commonly used as a biomarker for benzene exposure.
The presence of Hydroquinone (benzene-1,4-diol) in normal individuals stems mainly from direct dietary ingestion, catabolism of tyrosine and other substrates by gut bacteria, ingestion of arbutin containing foods, cigarette smoking, and the use of some over-the-counter medicines.


Hydroquinone (benzene-1,4-diol) is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone (benzene-1,4-diol) has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone (benzene-1,4-diol) is a white granular solid.


Substituted derivatives of this parent compound are also referred to as Hydroquinone (benzene-1,4-diol).
The name "Hydroquinone (benzene-1,4-diol)" was coined by Friedrich Wöhler in 1843.
In 2021, Hydroquinone (benzene-1,4-diol) was the 282nd most commonly prescribed medication in the United States, with more than 800,000 prescriptions.


Hydroquinone (benzene-1,4-diol) is thought to be the active toxin in Agaricus hondensis mushrooms.
Hydroquinone (benzene-1,4-diol) has been shown to be one of the chemical constituents of the natural product propolis.
Hydroquinone (benzene-1,4-diol) is also one of the chemical compounds found in castoreum.


Hydroquinone (benzene-1,4-diol) is gathered from the beaver's castor sacs.
Hydroquinone (benzene-1,4-diol) belongs to the class of organic compounds known as hydroquinone.
Hydroquinones (benzene-1,4-diol) are compounds containing a hydroquinone moiety, which consists of a benzene ring with a hydroxyl groups at positions 1 and 4.


Hydroquinone (benzene-1,4-diol) is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2.
Hydroquinone (benzene-1,4-diol)'s chemical structure has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone (benzene-1,4-diol) is a white granular solid at room temperature and pressure.


The hydroxyl groups of Hydroquinone (benzene-1,4-diol) are quite weakly acidic.
Hydroquinone (benzene-1,4-diol) can lose an H+ from one of the hydroxyls to form a monophenolate ion or lose an H+ from both to form a diphenolate ion.
Hydroquinone (benzene-1,4-diol) has a variety of uses principally associated with its action as a reducing agent which is soluble in water.


Hydroquinone (benzene-1,4-diol) is a major component of most photographic developers where, with the compound Metol, it reduces silver halides to elemental silver.
Hydroquinone (benzene-1,4-diol), also known quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.


Hydroquinone (benzene-1,4-diol) is used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene.
Hydroquinone (benzene-1,4-diol) reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.


Hydroquinone (benzene-1,4-diol) appears as a white to white-grayish powder.
Hydroquinone (benzene-1,4-diol) is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2.
Hydroquinone (benzene-1,4-diol)'s chemical structure, shown in the table at right, has two hydroxyl groups bonded to a benzene ring in a para position.


Hydroquinone (benzene-1,4-diol) is a white granular solid at room temperature and pressure.
Hydroquinone (benzene-1,4-diol) is an aromatic organic compound with a chemical formula C6H6O2.
Hydroquinone (benzene-1,4-diol) has two hydroxyl groups binding to a benzene ring in the para position.


Hydroquinone (benzene-1,4-diol) is a melanin synthesis Inhibitor.
Hydroquinone (benzene-1,4-diol) is also known as benzene-1, 4-diol or Quinol.
Hydroquinone (benzene-1,4-diol) is a derivative of phenol and has antioxidant properties.


Hydroquinone (benzene-1,4-diol) appears as a granular solid white in colour.
The name Hydroquinone (benzene-1,4-diol) was coined in the year 1843 by Friedrich Wohler.



USES and APPLICATIONS of HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinone (benzene-1,4-diol) has a variety of uses principally associated with its action as a reducing agent which is soluble in water.
Hydroquinone (benzene-1,4-diol) is a major component in most photographic developers where, with the compound Metol, it reduces silver halides to elemental silver.


In human medicine, Hydroquinone (benzene-1,4-diol) is used as a topical application in skin whitening to reduce the color of skin as it does not have the same predisposition to cause dermatitis as Metol does.
The disodium diphenolate salt of Hydroquinone (benzene-1,4-diol) is used as an alternating comonomer unit in the production of the polymer PEEK.


As a polymerization inhibitor, Hydroquinone (benzene-1,4-diol) prevents polymerization of acrylic acid, methyl methacrylate, etc.
Hydroquinone (benzene-1,4-diol) is also used as a raw material of herbicides, rubber antioxidants and dye stuffs.
Hydroquinone (benzene-1,4-diol) is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles.


Hydroquinone (benzene-1,4-diol) can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.
Hydroquinone (benzene-1,4-diol) is used as a developing agent in photography and as an antioxidant in rubber and food.


Hydroquinone (benzene-1,4-diol) is produced as an inhibitor, an antioxidant, and an intermediate in the synthesis of dyes, motor fuels, and oils; in photographic processing; and naturally in certain plant species,
Hydroquinone (benzene-1,4-diol) is used as a topical treatment for skin hyperpigmentation and in various cosmetic products.


In human medicine, Hydroquinone (benzene-1,4-diol) is used as a topical application in skin whitening to reduce the color of skin.
Hydroquinone (benzene-1,4-diol) has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone (benzene-1,4-diol) is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.


There are various other uses associated with Hydroquinone (benzene-1,4-diol)'s reducing power.
As a polymerisation inhibitor, exploiting its antioxidant properties, Hydroquinone (benzene-1,4-diol) prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.


By acting as a free radical scavenger, Hydroquinone (benzene-1,4-diol) serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone (benzene-1,4-diol) can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.


The disodium diphenolate salt of Hydroquinone (benzene-1,4-diol) is used as an alternating comonomer unit in the production of the polymer PEEK.
Hydroquinone (benzene-1,4-diol) is usually associated with use in skin lighteners.
Hydroquinone (benzene-1,4-diol) is commonly used as a biomarker for benzene exposure.


The presence of Hydroquinone (benzene-1,4-diol) in normal individuals stems mainly from direct dietary ingestion, catabolism of tyrosine and other substrates by gut bacteria, ingestion of arbutin-containing foods, cigarette smoking, and the use of some over-the-counter medicines.
Hydroquinone (benzene-1,4-diol) works by decreasing the production of melanin pigments in the skin.


Hydroquinone (benzene-1,4-diol) is used as a reducing agent.
Hydroquinone (benzene-1,4-diol) is used to treat melasma.
Hydroquinone (benzene-1,4-diol) is used in the prevention of methyl methacrylate.


Hydroquinone (benzene-1,4-diol) is used in skin whitening.
Hydroquinone (benzene-1,4-diol) is used for benzene exposure as a biomarker.
Hydroquinone (benzene-1,4-diol) is used by photographic developers.


Hydroquinone (benzene-1,4-diol) is used in the treatment of acne scars.
Hydroquinone (benzene-1,4-diol) is used in various cosmetic products.



PRODUCTION OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinone (benzene-1,4-diol) is produced industrially in two main ways.
The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene.

This compound reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and Hydroquinone (benzene-1,4-diol).

A second route involves hydroxylation of phenol over a catalyst.
The conversion uses hydrogen peroxide and affords a mixture of Hydroquinone (benzene-1,4-diol)and its ortho isomer catechol (benzene-1,2-diol):
C6H5OH+H2O2⟶C6H4(OH)2+H2O



ALTERNATIVE PARENTS OF HYDROQUINONE (BENZENE-1,4-DIOL):
*1-hydroxy-2-unsubstituted benzenoids
*Benzene and substituted derivatives
*Organooxygen compounds
*Hydrocarbon derivatives



SUBSTITUENTS OF HYDROQUINONE (BENZENE-1,4-DIOL):
*Hydroquinone
*1-hydroxy-2-unsubstituted benzenoid
*Monocyclic benzene moiety
*Organic oxygen compound
*Hydrocarbon derivative
*Organooxygen compound
*Aromatic homomonocyclic compound



THE MOST WIDELY USED INDUSTRIAL METHODS OF PRODUCING, HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinones (benzene-1,4-diol) are hydroxylation of phenol and cumene process.
Other less common methods are oxidation of various phenols, oxidation of aniline by manganese dioxide, and the dry distillation of quinic acid or from acetylene and iron pentacarbonyl.
Hydroquinone (benzene-1,4-diol) is widely used for benzene exposure as a biomarker.
Hydroquinone (benzene-1,4-diol) naturally occurs in the defensive glands of bombardier beetles.



NATURAL OCCURRENCES OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinones (benzene-1,4-diol) are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other chemicals, depending on the species), which collect in a reservoir.

The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
This chamber is lined with cells that secrete catalases and peroxidases.

When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the Hydroquinones (benzene-1,4-diol) into p-quinones.
These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.



OTHER, LESS COMMON METHODS INCLUDE:
A potentially significant synthesis of Hydroquinone (benzene-1,4-diol) from acetylene and iron pentacarbonyl has been proposed
Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.

Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.
Hydroquinone (benzene-1,4-diol) and its derivatives can also be prepared by oxidation of various phenols, such as aniline and DIPB.
Examples include Elbs persulfate oxidation and Dakin oxidation.

Hydroquinone (benzene-1,4-diol) was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.
Hydrolysis of chlorinated phenol, described as being used in China.
Note that methods such as hydrolysis of chlorinated phenol and oxidation of phenols are much more polluting methods than some others.



REACTIONS OF HYDROQUINONE (BENZENE-1,4-DIOL):
The reactivity of Hydroquinone (benzene-1,4-diol)'s hydroxyl groups resembles that of other phenols, being weakly acidic.
The resulting conjugate base undergoes easy O-alkylation to give mono- and diethers.

Similarly, Hydroquinone (benzene-1,4-diol) is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation.
This reaction is exploited en route to popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).
The useful dye quinizarin is produced by diacylation of Hydroquinone (benzene-1,4-diol) with phthalic anhydride.



REDOX OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinone (benzene-1,4-diol) undergoes oxidation under mild conditions to give benzoquinone.
This process can be reversed.

Some naturally occurring Hydroquinone (benzene-1,4-diol) derivatives exhibit this sort of reactivity, one example being coenzyme Q.
Industrially this reaction is exploited both with Hydroquinone (benzene-1,4-diol) itself but more often with its derivatives where one OH has been replaced by an amine.

When colorless Hydroquinone (benzene-1,4-diol) and benzoquinone, a bright yellow solid, are cocrystallized in a 1:1 ratio, a dark-green crystalline charge-transfer complex (melting point 171 °C) called quinhydrone (C6H6O2·C6H4O2) is formed.
This complex dissolves in hot water, where the two molecules dissociate in solution.



AMINATION OF HYDROQUINONE (BENZENE-1,4-DIOL):
An important reaction is the conversion of Hydroquinone (benzene-1,4-diol) to the mono- and diamine derivatives. Methylaminophenol, used in photography, is produced in this way:
C6H4(OH)2+CH3NH2methylamine⟶HOC6H4NHCH3+H2O
Diamines, useful in the rubber industry as antiozone agents, are similarly produced from aniline:
C6H4(OH)2+2C6H5NH2aniline⟶C6H4(N(H)C6H5)2+2H2O



SKIN DEPIGMENTATION OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinone (benzene-1,4-diol) is used as a topical application in skin whitening to reduce the color of skin.
Hydroquinone (benzene-1,4-diol) does not have the same predisposition to cause dermatitis as metol does.
This is a prescription-only ingredient in some countries, including the member states of the European Union under Directives 76/768/EEC:1976.



NATURAL OCCURRENCES OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinones (benzene-1,4-diol) are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.

The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
This chamber is lined with cells that secrete catalases and peroxidases.
When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the Hydroquinones (benzene-1,4-diol) into p-quinones.

These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.



NOMENCLATURE OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinone (benzene-1,4-diol) is the name recommended by the International Union of Pure and Applied Chemistry (IUPAC) in its 1993 Recommendations for the Nomenclature of Organic Chemistry.



PROPERTIES OF HYDROQUINONE (BENZENE-1,4-DIOL):
Hydroquinone (benzene-1,4-diol) can undergo mild oxidation to convert to the compound parabenzoquinone, C6H4O2, often called p-quinone or simply quinone.
Reduction of quinone reverses this reaction back to Hydroquinone (benzene-1,4-diol).

Some biochemical compounds in nature have this sort of Hydroquinone (benzene-1,4-diol) or quinone section in their structures, such as Coenzyme Q, and can undergo similar redox interconversions.
The hydroxyl groups of Hydroquinone (benzene-1,4-diol) are quite weakly acidic.
Hydroquinone (benzene-1,4-diol) can lose an H+ from one of the hydroxyls to form a monophenolate ion or lose an H+ from both to form a diphenolate ion.



PHYSICAL and CHEMICAL PROPERTIES of HYDROQUINONE (BENZENE-1,4-DIOL):
Molecular Weight: 110.11
Appearance Form: crystalline
Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: 3,7 at 70 g/l
Melting point/freezing point:
Melting point/range: 172 - 175 °C - lit.
Initial boiling point and boiling range: 285 °C - lit.
Flash point: 165 °C at ca.1.013 hPa
Evaporation rate: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 1 hPa at 132 °C
Vapor density: 3,80 - (Air = 1.0)

Density: 1,332 g/cm3 at 15 °C
Relative density: No data available
Water solubility 72 g/l at 25 °C - completely soluble
Partition coefficient: n-octanol/water
log Pow: 0,59 - Bioaccumulation is not expected.
Autoignition temperature: 515,56 °C at 1.013 hPa
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Relative vapor density: 3,80 - (Air = 1.0)
Water Solubility: 95.5 g/L

logP: 0.71
logP: 1.37
logS: -0.06
pKa (Strongest Acidic): 9.68
pKa (Strongest Basic): -5.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 2
Polar Surface Area: 40.46 Ų
Rotatable Bond Count: 0
Refractivity: 30.02 m³·mol⁻¹
Polarizability: 10.75 ų
Number of Rings: 1
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No

Veber's Rule: No
MDDR-like Rule: No
IUPAC Name: benzene-1,4-diol
Traditional IUPAC Name: α-hydroquinone
Formula: C6H6O2
InChI: InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
InChI Key: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
Molecular weight: 110.1106
Exact mass: 110.036779436
SMILES: OC1=CC=C(O)C=C1
Chemical Formula: C6H6O2
Average Molecular Weight: 110.1106
Monoisotopic Molecular Weight: 110.036779436
IUPAC Name: benzene-1,4-diol
Traditional Name: α-hydroquinone

CAS Registry Number: 123-31-9
SMILES: OC1=CC=C(O)C=C1
InChI Identifier: InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
InChI Key: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
Melting Point: 170.0°C to 174.0°C
Color: White
Density: 1.32
Boiling Point: 285.0°C to 287.0°C
Flash Point: 165°C
Infrared Spectrum: Authentic
Assay Percent Range: 98.5% min. (HPLC)
Beilstein: 06, 836

Fieser: 05,341; 14,249
Merck Index: 15, 4845
Solubility Information: Solubility in water: 70g/L in water (20°C).
Other solubilities: soluble in alcohol and ether,slightly soluble in benzene,
readily soluble in ethanol,acetone and methanol
Formula Weight: 110.11
Percent Purity: 99%
Physical Form: Needle-like Crystals or Crystalline Powder
Chemical Name or Material: Hydroquinone, 99%
C6H6O2: Hydroquinone
Molecular Weight/ Molar Mass: 110.11 g/mol
Density: 1.3 g cm−3
Boiling Point: 287 °C
Melting Point: 172 °C



FIRST AID MEASURES of HYDROQUINONE (BENZENE-1,4-DIOL):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROQUINONE (BENZENE-1,4-DIOL):
-Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROQUINONE (BENZENE-1,4-DIOL):
-Extinguishing media:
*Suitable extinguishing media:
Water Foam Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROQUINONE (BENZENE-1,4-DIOL):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use safety goggles.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Use protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROQUINONE (BENZENE-1,4-DIOL):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
*Hygiene measures:
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROQUINONE (BENZENE-1,4-DIOL):
-Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .


HYDROQUINONE (QUINOL)
DESCRIPTION:
Hydroquinone (quinol), also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2.
Hydroquinone (quinol) has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone (quinol) is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones.
The name "hydroquinone" was coined by Friedrich Wöhler in 1843.

CAS Number: 123-31-9
EC Number: 204-617-8
IUPAC Name: benzene-1,4-diol
Molecular Formula: C6H6O2


Hydroquinone (quinol) is an aromatic organic compound with the chemical formula C6H4(OH)2, also known as benzene-1,4-diol or quinol, which is a kind of phenol and also a derivative of benzene.
Hydroquinone (quinol) contains two hydroxyl groups bonded in a para position to the benzene ring.
Hydroquinone (quinol) is a granular white solid.

This parent compound’s substituted derivatives are also known as hydroquinones.
Friedrich Wöhler coined the term “hydroquinone” in 1843.


Hydroquinone (quinol) appears as light colored crystals or solutions.
May irritate the skin, eyes and mucous membranes.
Mildly toxic by ingestion or skin absorption.


Hydroquinone (quinol) is a benzenediol comprising benzene core carrying two hydroxy substituents para to each other.
Hydroquinone (quinol) has a role as a cofactor, a carcinogenic agent, an Escherichia coli metabolite, a human xenobiotic metabolite, a skin lightening agent, an antioxidant and a mouse metabolite.
Hydroquinone (quinol) is a benzenediol and a member of hydroquinones.

Hydroquinone (quinol) is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles.
Hydroquinone (quinol) can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen.

Hydroquinone (quinol) has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity.
As a result of these concerns, Hydroquinone (quinol) has been banned in the EU and UK.







PRODUCTION OF HYDROQUINONE (QUINOL):
Hydroquinone (quinol) is produced industrially in two main ways.
The most widely used route is similar to the cumene process in reaction mechanism and involves the dialkylation of benzene with propene to give 1,4-diisopropylbenzene.
Hydroquinone (quinol) reacts with air to afford the bis(hydroperoxide), which is structurally similar to cumene hydroperoxide and rearranges in acid to give acetone and hydroquinone.


A second route involves hydroxylation of phenol over a catalyst.
The conversion uses hydrogen peroxide and affords a mixture of hydroquinone and its ortho isomer catechol (benzene-1,2-diol):
C6H5OH+H2O2⟶C6H4(OH)2+H2O


Other, less common methods include:
A potentially significant synthesis of hydroquinone from acetylene and iron pentacarbonyl has been proposed
Iron pentacarbonyl serves as a catalyst, rather than as a reagent, in the presence of free carbon monoxide gas.
Rhodium or ruthenium can substitute for iron as the catalyst with favorable chemical yields but are not typically used due to their cost of recovery from the reaction mixture.


Hydroquinone (quinol) and its derivatives can also be prepared by oxidation of various phenols, such as aniline and DIPB.
Examples include Elbs persulfate oxidation and Dakin oxidation.
Hydroquinone (quinol) was first obtained in 1820 by the French chemists Pelletier and Caventou via the dry distillation of quinic acid.

Hydrolysis of chlorinated phenol, described as being used in China.
Note that methods such as hydrolysis of chlorinated phenol and oxidation of phenols are much more polluting methods than some others.

Industrial production of hydroquinone usually happens in two ways.
The most commonly used technique is identical to the cumene process in the reaction mechanism and, it includes the dialkylation of benzene with propene to produce 1,4-diisopropyl benzene.
The compound reacts with air to form bishydroperoxide, which has a similar structure compared to cumene hydroperoxide and, it rearranges in acid to form acetone and hydroquinone.


The second method includes the hydroxylation of phenol over a catalyst.
The conversion process uses hydrogen peroxide and provides a combination of hydroquinone and catechol (benzene-1,2-diol):
C6H5OH+H2O2⟶C6H4(OH)2+H2O


Some other methods for producing hydroquinone are:
Oxidation of various phenols can also produce hydroquinone and its derivatives.
Examples of such method are Elbs persulfate oxidation and Dakin oxidation.
French chemists Pelletier and Caventou first obtained hydroquinone in 1820 through the dry distillation process of quinic acid.





REACTIONS OF HYDROQUINONE (QUINOL):
The reactivity of hydroquinone's hydroxyl groups resembles that of other phenols, being weakly acidic.
The resulting conjugate base undergoes easy O-alkylation to give mono- and diethers.
Similarly, hydroquinone is highly susceptible to ring substitution by Friedel–Crafts reactions such as alkylation.


This reaction is exploited en route to popular antioxidants such as 2-tert-butyl-4-methoxyphenol (BHA).
The useful dye quinizarin is produced by diacylation of hydroquinone with phthalic anhydride.


Redox:
Hydroquinone undergoes oxidation under mild conditions to give benzoquinone.
This process can be reversed.
Some naturally occurring hydroquinone derivatives exhibit this sort of reactivity, one example being coenzyme Q.

Industrially this reaction is exploited both with hydroquinone itself but more often with its derivatives where one OH has been replaced by an amine.
When colorless hydroquinone and benzoquinone, a bright yellow solid, are cocrystallized in a 1:1 ratio, a dark-green crystalline charge-transfer complex (melting point 171 °C) called quinhydrone (C6H6O2•C6H4O2) is formed.
This complex dissolves in hot water, where the two molecules dissociate in solution.

Amination:
An important reaction is the conversion of hydroquinone to the mono- and diamine derivatives.
Methylaminophenol, used in photography, is produced in this way:
C6H4(OH)2+CH3NH2methylamine⟶HOC6H4NHCH3+H2O

Diamines, useful in the rubber industry as antiozone agents, are similarly produced from aniline:
C6H4(OH)2+2C6H5NH2aniline⟶C6H4(N(H)C6H5)2+2H2O

USES OF HYDROQUINONE (QUINOL):
Hydroquinone (quinol) has a variety of uses principally associated with its action as a reducing agent that is soluble in water.
Hydroquinone (quinol) is a major component in most black and white photographic developers for film and paper where, with the compound metol, it reduces silver halides to elemental silver.
There are various other uses associated with its reducing power.

As a polymerisation inhibitor, exploiting its antioxidant properties, hydroquinone prevents polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers that are susceptible to radical-initiated polymerization.
By acting as a free radical scavenger, hydroquinone serves to prolong the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone can lose a hydrogen cation from both hydroxyl groups to form a diphenolate ion.

The disodium diphenolate salt of hydroquinone is used as an alternating comonomer unit in the production of the polymer PEEK.


Skin depigmentation:
Hydroquinone (quinol) is used as a topical application in skin whitening to reduce the color of skin.
Hydroquinone (quinol) does not have the same predisposition to cause dermatitis as metol does.
This is a prescription-only ingredient in some countries, including the member states of the European Union under Directives 76/768/EEC:1976.


In 2006, the United States Food and Drug Administration revoked its previous approval of hydroquinone and proposed a ban on all over-the-counter preparations.
The FDA officially banned hydroquinone in 2020 as part of a larger reform of the over-the-counter drug review process.
The FDA stated that hydroquinone cannot be ruled out as a potential carcinogen.

This conclusion was reached based on the extent of absorption in humans and the incidence of neoplasms in rats in several studies where adult rats were found to have increased rates of tumours, including thyroid follicular cell hyperplasias, anisokaryosis (variation in nuclei sizes), mononuclear cell leukemia, hepatocellular adenomas and renal tubule cell adenomas.
The Campaign for Safe Cosmetics has also highlighted concerns.


Numerous studies have revealed that hydroquinone, if taken orally, can cause exogenous ochronosis, a disfiguring disease in which blue-black pigments are deposited onto the skin; however, skin preparations containing the ingredient are administered topically.
The FDA had classified hydroquinone in 1982 as a safe product - generally recognized as safe and effective (GRASE), however additional studies under the National Toxicology Program (NTP) were suggested in order to determine whether there is a risk to humans from the use of hydroquinone.


NTP evaluation showed some evidence of long-term carcinogenic and genotoxic effects
While hydroquinone remains widely prescribed for treatment of hyperpigmentation, questions raised about its safety profile by regulatory agencies in the EU, Japan, and USA encourage the search for other agents with comparable efficacy.
Several such agents are already available or under research, including azelaic acid, kojic acid, retinoids, cysteamine, topical steroids, glycolic acid, and other substances.

One of these, 4-butylresorcinol, has been proved to be more effective at treating melanin-related skin disorders by a wide margin, as well as safe enough to be made available over the counter.

The uses of hydroquinone are:
Hydroquinone is used As a reducing agent.
Hydroquinone is used For the preventive measures of methyl methacrylate.
Hydroquinone is used In skin whitening.


Hydroquinone is used Helpful as a biomarker for benzene exposure.
Hydroquinone is used By photographic developers
Hydroquinone is used In the treatment of acne scars
Hydroquinone is used In various cosmetic products


APPLICATIONS OF HYDROQUINONE
Hydroquinone has several applications, which are primarily associated with its function as a reducing agent that is soluble in water. It is a major component of most black and white photographers for film and paper where, with the compound metol, it transforms silver halides into elemental silver.
There are several other applications for its reducing power. As a polymerization barrier, hydroquinone inhibits the polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers vulnerable to radical-initiated polymerization by using its antioxidant properties.
By serving as a free-radical scavenger, hydroquinone helps in improving the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone can form a diphenolate ion by losing a hydrogen cation from both hydroxyl groups.







NATURAL OCCURRENCES OF HYDROQUINONE (QUINOL):
Hydroquinones are one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other compounds, depending on the species), which collect in a reservoir.
The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
This chamber is lined with cells that secrete catalases and peroxidases. When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the hydroquinones into p-quinones.

These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.
Hydroquinone (quinol) is thought to be the active toxin in Agaricus hondensis mushrooms.

Hydroquinone (quinol) has been shown to be one of the chemical constituents of the natural product propolis.
Hydroquinone (quinol) is also one of the chemical compounds found in castoreum.
Hydroquinone (quinol) is gathered from the beaver's castor sacs.

SAFETY INFORMATION ABOUT HYDROQUINONE (QUINOL):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product





QUESTIONS AND ANSWERS ABOUT HYDROQUINONE (QUINOL):
Q.1. How is hydroquinone used in hyperpigmentation treatment?
Answer. Hydroquinone is useful in lightening the dark areas of skin, also known as hyperpigmentation, melasma, “liver marks,” “ageing spots,” and freckles that occur due to pregnancy, birth control drugs, hormone therapy, or damage to the skin.
This drug works by suppressing the process in the skin that leads to discolouration.


Q.2. What is an appropriate alternative for hydroquinone?
Answer. Mequinol (4-Hydroxyanisole) is the most common prescription substitute for hydroquinone.
Methoxy phenol is also known as monomethyl ether with hydroquinone and p-hydroxyanisole.
Hydroquinone is equally as effective as hydroquinone.

Q.3. What are the side-effects of hydroquinone?
Answer. The most common side-effects of hydroquinone are mild burning, stinging, redness, and dryness may occur.
Unlikely but serious side effects that occur include blistering, skin cracking, blue-black darkening of the skin.
Rare side-effects that may occur include symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing



CHEMICAL AND PHYSICAL PROPERTIES OF HYDROQUINONE (QUINOL):
Chemical formula, C6H6O2
Molar mass, 110.112 g•mol−1
Appearance, White solid
Density, 1.3 g cm−3, solid
Melting point, 172 °C (342 °F; 445 K)
Boiling point, 287 °C (549 °F; 560 K)
Solubility in water, 5.9 g/100 mL (15 °C)
Vapor pressure, 10−5 mmHg (20 °C)[2]
Acidity (pKa), 9.9[3]
Magnetic susceptibility (χ), −64.63×10−6 cm3/mol
Molecular Weight
110.11 g/mol
Computed by PubChem 2.1 (PubChem release 2021.05.07)
XLogP3
0.6
Computed by XLogP3 3.0 (PubChem release 2021.05.07)
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Rotatable Bond Count
0
Exact Mass
110.036779430 g/mol
Monoisotopic Mass
110.036779430 g/mol
Topological Polar Surface Area
40.5Ų
Heavy Atom Count
8
Formal Charge
0
Complexity
54.9
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes






SYNONYMS OF HYDROQUINONE (QUINOL):
1,4-benzenediol
1,4-dihydroxybenzene
Artra
beta-quinol
Eldopaque
Eldoquin
Esoterica
Hidroquilaude
Hidroquin
Hidroquinona Isdin
hydroquinone
hydroquinone, copper (1+) salt
hydroquinone, lead (2+) salt (2:1)
hydroquinone, monocopper (2+) salt
Licostrata
Lustra
Melanasa
Melanex
Melpaque
Melquin
Neostrata HQ
p-benzenediol
Phiaquin
Solaquin
Ultraquin
hydroquinone
Benzene-1,4-diol
123-31-9
1,4-benzenediol
Quinol
1,4-Dihydroxybenzene
p-Benzenediol
p-Hydroquinone
p-Hydroxyphenol
4-Hydroxyphenol
p-Dihydroxybenzene
Benzoquinol
hydroquinol
Eldoquin
p-Dioxybenzene
Solaquin forte
Dihydroquinone
Eldopaque
Hydroquinole
Idrochinone
Tecquinol
Phiaquin
Benzohydroquinone
Hidroquinone
Arctuvin
Tequinol
Dihydroxybenzene
Eldopaque Forte
Eldoquin Forte
Derma-Blanch
Hydrochinon
Tenox HQ
Diak 5
Benzene, p-dihydroxy-
Hydrochinone
1,4-Dihydroxy-benzol
Artra
Usaf ek-356
1,4-Diidrobenzene
p-Dioxobenzene
1,4-Dihydroxybenzen
para-Dioxybenzene
para-Hydroquinone
NCI-C55834
Black and White Bleaching Cream
1,4-Dihydroxy-benzeen
para-Dihydroxybenzene
beta-quinol
HE 5
Pyrogentistic acid
Epiquin
Melanex
Sunvanish
Idrochinone [Italian]
p-Dihydroquinone
alpha-hydroquinone
CHEBI:17594
NSC 9247
Hydrochinon [Czech, Polish]
CCRIS 714
1,4-Dihydroxybenzen [Czech]
1,4-Diidrobenzene [Italian]
HSDB 577
DTXSID7020716
1,4-Dihydroxy-benzeen [Dutch]
1,4-Dihydroxy-benzol [German]
AI3-00072
CHEMBL537
UNII-XV74C1N1AE
NSC-9247
EINECS 204-617-8
XV74C1N1AE
UN2662
Hydroquinone (USP)
Hydroquinone [USP]
MFCD00002339
HQ
DTXCID70716
NSC9247
EC 204-617-8
Hydroquinone [UN2662] [Poison]
1,4-Dihydroxybenzene (ring-d4)
TRI-LUMA COMPONENT HYDROQUINONE
NCGC00015523-02
HYDROQUINONE COMPONENT OF TRI-LUMA
HYDROQUINONE (IARC)
HYDROQUINONE [IARC]
para-Hydroxyphenol
HYDROQUINONE (MART.)
HYDROQUINONE [MART.]
HYDROQUINONE (USP-RS)
HYDROQUINONE [USP-RS]
quinnone
Eldopacque
p-Phenylenediol
p Benzendiol
HYDROQUINONE (USP MONOGRAPH)
HYDROQUINONE [USP MONOGRAPH]
p-Quinol
1,4-Benzoquinol
CAS-123-31-9
SMR000059154
1,4-Hydroxybenzene
SR-01000075920
BUTYLHYDROXYANISOLE IMPURITY A (EP IMPURITY)
BUTYLHYDROXYANISOLE IMPURITY A [EP IMPURITY]
4-DIHYDROXYBENZENE
hydroquinon
BQ(H)
Hydroquinoue
Balancer
MedisilkeNight
Supermax
hydroq uinone
hydroquinone gr
MiracleFade
Reduced quinone
a-Hydroquinone
Activator Light
Corrector Light
Skin Lightener
Black & White Bleaching Cream
Clear Action
Double White
Exence White
Hydroquinone gel
Idole Carrot
Movate Carrot
Movate Lemon
p-Hydroxybenzene
Scarlight Md
b-Quinol
Caro Light
Hot Movate
Idole Black
4-Benzenediol
Hydroquinone 4%
Hydroquinone cream
Nova Complex HQ
Hydroquinone, HQ
Light The Way
.beta.-Quinol
1,4 benzenediol
Clarite 4
Hydro-Q
Obagi-C
Seequin 2
Seequin 4
Active 4
Hydroquinone,(S)
p-dihydroxy benzene
PLQ
Artra (Salt/Mix)
HQLA
HYDROP
I-max Lightening 5
PIONA
.alpha.-Hydroquinone
Skin lightening Cream
African Formula Black
NeovaComplex HQ Plus
phenol derivative, 4
Skin Beautifying Milk
African Formula Carrot
Essential Fade Complex
Clear-N-Smooth PLUS
4-hydroxyphenyl alcohol
NU-DERM BLENDER
NU-DERM CLEAR
Skin Lightening Complex
Spectrum_001757
SYMBA Skin Lightening
4e3h
Image Md Lightening Rx
BRIGHTENLIGHTENING
HYDROQUINONE 6%
HYDROQUINONE 8%
SpecPlus_000769
1,4-Dihydrobenzoquinone
Clear-N-Smooth Ultimate
Clear-N-Smooth SuperMax
Clear-N-Smooth UltraMax
ELDOQUIN (TN)
EB5 Age Spot Treatment
Gold Cosmetics Adi Clear
hydroquinone for synthesis
Hydroquinone Time Release
Rejuvaderm Medispa Fading
Spectrum2_001672
Spectrum3_000656
Spectrum4_000633
Spectrum5_001430
HYDROQUINONE [MI]
Lopac-H-9003
HYDROQUINONE 8%.
WLN: QR DQ
bmse000293
Dark Spot Lightening Cream
Epitope ID:116206
Sh18
HYDROQUINONE [HSDB]
HYDROQUINONE [INCI]
Skin LighteningRodan Fields
PLUS Skin lightening Cream
Gold Cosmetics Bleach Cream
Vividly Brilliant Perfecting
HYDROQUINONE [VANDF]
1,4-Dihydroxybenzene Quinol
Lopac0_000577
SCHEMBL15516
BSPBio_002291
KBioGR_001246
KBioSS_002237
1,4-Dihydroxybenzene, XIII
MLS000069815
MLS001074911
Pure Valley Miracle Age Spot
BIDD:ER0340
DivK1c_006865
HYDROQUINONE [WHO-DD]
Hydroquinone, LR, >=99%
SPECTRUM1504237
Clear-N-Smooth Super-Ultimate
Hydrochinon(CZECH, POLISH)
SPBio_001883
Precious Beauty Skin Lightening
Body Fade CremeMaximum Strength
PLEXADERM Dark Spot Fade Gel
ULTIMATE Skin lightening Cream
BDBM26190
Hydroquinone, puriss., 99.0%
KBio1_001809
KBio2_002237
KBio2_004805
KBio2_007373
KBio3_001511
Benzene-1,4-diol (Hydroquinone)
Gold Cosmetics Bleach Cream Forte
HQ Plus Brightening CreamVI Derm
HMS1922H15
HMS2093E08
HMS3261D16
HYDROQUINONE [ORANGE BOOK]
OLIVIA QUIDO BLEMISH ERASER
Pharmakon1600-01504237
Ageless Total Skin Bleaching Serum
DermisaSkin Fade Vitamin C infused
Gold Cosmetics Bleach Cream Silver
Divine Derrier Skin Bleaching cream
Dr. Lightening Ultra-Potent Facial
HY-B0951
Obagi-C Rx system C-Therapy Night
Tox21_110169
Tox21_202345
Tox21_300015
Tox21_500577
141010 HYDROQUINONE 4%
141011 HYDROQUINONE 6%
141030 HYDROQUINONE 8%
141055 HYDROQUINONE 6%
141067 HYDROQUINONE 8%
CCG-39082
MD Acne Medicated Dark Spot Remover
NSC758707
Olivia Quido Skincare Blemish Eraser
s4580
AKOS000119003
Obagi C Rx System C Clarifying Serum
Teatrical Pro-Aclarant Skin Lightening
Tox21_110169_1
AM10548
DB09526
LP00577
NSC-758707
SDCCGSBI-0050559.P003
UN 2662
Hydroquinone, ReagentPlus(R), >=99%
Hydroquinone, USP, 99.0-100.5%
NCGC00015523-01
NCGC00015523-03
NCGC00015523-04
NCGC00015523-05
NCGC00015523-06
NCGC00015523-07
NCGC00015523-08
NCGC00015523-09
NCGC00015523-10
NCGC00015523-11
NCGC00015523-12
NCGC00015523-13
NCGC00015523-19
NCGC00090880-01
NCGC00090880-02
NCGC00090880-03
NCGC00090880-04
NCGC00090880-05
NCGC00254037-01
NCGC00259894-01
NCGC00261262-01
BP-21160
Dr. Throwers Skin Lightening Moisturizing
Hydroquinone, ReagentPlus(R), >=99.5%
SBI-0050559.P002
Hydroquinone, SAJ first grade, >=99.0%
NU-DERM CLEARSkin Bleaching and Corrector
EU-0100577
FT-0606877
H0186
Hydroquinone, SAJ special grade, >=99.0%
MEDITOWELILLUMINATING SKIN BRIGHTENING
NU-DERM BLENDERSkin Lightener and Blending
EN300-18053
Hydroquinone, meets USP testing specifications
Advanced Dual Complex FadeMaximum Strength Plus
C00530
D00073
H 9003
AB00053361_08
Quinol; 1,4-Benzenediol; 1,4-Dihydroxybenzene
Q419164
ZO Skin Health Pigment Control Creme Hydroquinone
J-004910
J-521469
SR-01000075920-1
SR-01000075920-4
Q27102742
Z57127551
094CADDB-59BF-4EDF-B278-59791B203EA2
F1908-0167
Hydroquinone, certified reference material, TraceCERT(R)
OBAGI-C Rx system C-CLARIFYING SERUM NORMAL TO oily
ZO Skin Health Pigment Control Program Plus Hydroquinone
CONDITION AND ENHANCE BLENDERSkin Lightener and Blending
CONDITION AND ENHANCE CLEARSkin Bleaching and Corrector
ZO Skin Health Pigment Control Plus Blending Creme Hydroquinone
ELASTIDERM DECOLLETAGE SKIN LIGHTENING COMPLEXChest and Neck
Hydroquinone, United States Pharmacopeia (USP) Reference Standard
InChI=1/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8
Obagi-C Rx system C-Therapy NightSkin Lightening with Vitamins C and E
Hydroquinone, Pharmaceutical Secondary Standard; Certified Reference Material
ZO MEDICAL MELAMIN-C Skin Bleaching and Correcting with Vitamin C Hydroquinone
ZO Skin Health Pigment Control plus Brightening Creme Hydroquinone plus Vitamin C
OBAGI-C Rx system C-CLARIFYING SERUM NORMAL TO oilySKIN LIGHTENING SERUM WITH VITAMIN C


HYDROQUINONE (QUINOL)
Hydroquinone (quinol) is a granular white solid.
Hydroquinone (quinol) is a skin-lightening agent.
Its chemical formula is C6H4(OH)2, Hydroquinone (quinol) is also known as benzene-1,4-diol or quinol.


CAS Number: 123-31-9
EC Number: 204-617-8
MDL number: MFCD00002339
Molecular Formula: C6H6O2 / C6H4-1,4-(OH)2 / C6H4(OH)2



SYNONYMS:
Hydroquinone, Idrochinone, Quinol, 1,4-Dihydroxybenzene, p-dihydroxybenzene, 1,4-Hydroxy benzene, 1,4-Benzenediol, HQ, 1,4-Dihydroxybenzene, Hydroquinone, Quinol, P-Hydroquinone, Hydrochinon, Dihydroquinone, Hydroquinol, Benzoquinol, Hydrochinone, Hidroquinone, Hidroquin, Idrochinone, Para-Hydroquinone, Hydroquinole, Hidroquilaude, 1, 4-Dihydroxy-Benzeen, 1, 4-Diidrobenzene, Pyrogentistic Acid, Hydroquinoue, Ccris 714, Diak 5, 1,4-Benzenediol, 1,4-Dihydroxybenzene, 4-Hydroxyphenol, Benzene-1,4-diol, Eldoquin, Hydroquinone, hydroquinone, p-Benzenediol, p-Hydroquinone, p-hydroxyphenol, Quinol, 1,4-benzenediol, benzene-1,4-diol, p-dihydroxybenzene, 1,4-dihydroxybenzene, hydroquinol, p-hydroquinone, hydroquinone, 123-31-9, Benzene-1,4-diol, 1,4-benzenediol, Quinol, 1,4-Dihydroxybenzene, p-Benzenediol, p-Hydroquinone, Dihydroquinone, 1,4-Dihydroxybenzene, Quinol, 1,4-benzenediol, p Benzendiol, Benzoquinol, para-Hydroxyphenol, Dihydroxybenzene, 1,4-Hydroxybenzene, p-Hydroquinone, p-Dihydroxybenzene, 1,4-Benzendil, Aida, Black and White Bleaching Cream, Eldoquin, Elopaque, quinnone, Tecquinol, Hydroquinol, p-Diphenol, Hydrochinon, hydrokinone, p-benzenediol, p-dioxobenzene, alpha-hydroquinone, benzohydroquinone, beta-quinol, arctuvin, eldopaque, tenox hq, tequinol, Benzene-1,4-diol, HQ, 1,4-Benzenediol, p-Benzenediol, p-Dihydroxybenzene, p-Dioxybenzene, p-Hydroquinone, p-Hydroxyphenol, Arctuvin, Benzohydroquinone, Benzoquinol, Diak 5, Eldopaque, Eldoquin, Hidroquinone, Hydroquinol, HE 5, Phiaquin, Quinol, Tecquinol, Tenox HQ, 1,4-Dihydroxybenzene, 4-Hydroxyphenol, p-Dioxobenzene, Hydrochinone, Benzene, p-dihydroxy-, Black and White Bleaching Cream, Derma-Blanch, Hydrochinon, Hydroquinole, Idrochinone, NCI-C55834, Tequinol, USAF EK-356, 1,4-Dihydroxy-benzeen, 1,4-Dihydroxy-benzol, 1,4-Dihydroxybenzen, 1,4-Diidrobenzene, UN 2662, Dihydroquinone, Aida, Eldopacque, Eldopaque forte, Eldoquin forte, Solaquin forte, p-Dihydroquinone, Black & White Bleaching Cream, 1,4-Benzenediol (hydroquinone), Artra (Salt/Mix) p-Hydroxyphenol, 4-Hydroxyphenol, p-Dihydroxybenzene, Benzoquinol, hydroquinol, Dihydroquinone, Eldoquin, p-Dioxybenzene, Solaquin forte, Eldopaque, Hydroquinole, Idrochinone, Tecquinol, Phiaquin, Benzohydroquinone, Hidroquinone, Arctuvin, Tequinol, Dihydroxybenzene, Eldopaque Forte, Eldoquin Forte, Hydrochinon, Tenox HQ, Diak 5, Benzene, p-dihydroxy-, Hydrochinone, 1,4-Dihydroxy-benzol, Artra, Usaf ek-356, 1,4-Diidrobenzene, p-Dioxobenzene, 1,4-Dihydroxybenzen, para-Dioxybenzene, para-Hydroquinone, NCI-C55834, para-Dihydroxybenzene, beta-quinol, HE 5, Pyrogentistic acid, Epiquin, Melanex, Sunvanish, p-Dihydroquinone, alpha-hydroquinone, CHEBI:17594, NSC 9247, HSDB 577, DTXSID7020716, AI3-00072, CHEMBL537, UNII-XV74C1N1AE, NSC-9247, EINECS 204-617-8, XV74C1N1AE, UN2662, Hydroquinone (USP), Hydroquinone [USP], MFCD00002339, HQ, DTXCID70716, NSC9247, EC 204-617-8, Hydroquinone, TRI-LUMA COMPONENT HYDROQUINONE, NCGC00015523-02, quinnone, Eldopacque, p-Phenylenediol, p Benzendiol, p-Quinol, 1,4-Benzoquinol, CAS-123-31-9, SMR000059154, 1,4-Hydroxybenzene, SR-01000075920, 4-DIHYDROXYBENZENE, hydroquinon, BQ(H), Hydroquinoue, Balancer, MedisilkeNight, Supermax, hydroq uinone, hydroquinone gr, MiracleFade, Reduced quinone, a-Hydroquinone, Hydroquinone gel, Idole Carrot, Movate Carrot, Movate Lemon, p-Hydroxybenzene, Scarlight Md, b-Quinol, Caro Light, Hot Movate, Idole Black, 4-Benzenediol, Hydroquinone 4%, 1,4 benzenediol, Clarite 4, Hydro-Q, Obagi-C, Active 4, Hydroquinone,(S), p-dihydroxy benzene, PLQ, HQLA, HYDROP, 4-hydroxyphenyl alcohol, Spectrum_001757, Lopac-H-9003, HYDROQUINONE 8%., WLN: QR DQ, bmse000293, Sh18, Lopac0_000577, SCHEMBL15516, BSPBio_002291, KBioGR_001246, KBioSS_002237, 1,4-Dihydroxybenzene, XIII, MLS000069815, MLS001074911, HYDROQUINONE [WHO-DD], Hydroquinone, LR, >=99%, SPECTRUM1504237, s4580, AKOS000119003, Tox21_110169_1, AM10548, DB09526, LP00577, NSC-758707, RP10102, SDCCGSBI-0050559.P003, UN 2662, BP-21160, EU-0100577, FT-0606877, EN300-18053, C00530, D00073, H 9003, AB00053361_08, Q419164, J-004910,
J-521469, SR-01000075920-1, SR-01000075920-4, Q27102742, Z57127551, F1908-0167, Benzene-1,4-diol, Hydroquinone, Idrochinone, Quinol, 1,4-Dihydroxybenzene,
p-dihydroxybenzene, p-hydroxyphenol, 1,4-Hydroxy benzene, Calcium Dobesilate Monohydrate Imp. A (EP), Dobesilate Imp. A (EP), Hydroquinone, 1,4-Benzoquinol, 1,4-Dihydroxybenzene, 1,4-Phenylenediol, 1,4-p-Benzenediol, 4-Hydroxyphenol, Aida, Arctuvin, BQ(H), Benzohydroquinone, Benzoquinol, Black & White Bleaching Cream, Diak 5, Dihydroquinone, Eldopacque, Eldopaque, Eldopaque Forte, Eldoquin, Eldoquin Forte, HE 5, Hydroquinol, NSC 9247, Phiaquin, Quinol, Solaquin Forte, Solution Q, Tecquinol, Tenox HQ, p-Benzenediol, p-Dihydroquinone, p-Dihydroxybenzene, p-Dioxybenzene, p-Hydroquinone, p-Hydroxyphenol, p-Phenylenediol, p-Quin, Calcium Dobesilate Monohydrate Impurity A, Etamsylate Impurity A, Calcium Dobesilate Impurity A, 1,4-Benzenediol, 1,4-Dihydroxybenzene, 4-Hydroxyphenol, Benzene-1,4-diol, Eldoquin, p-Benzenediol, p-Hydroquinone, p-Hydroxyphenol, Quinol, Artra, Eldopaque, Esoterica, Hidroquilaude, Hidroquin, Hidroquinona isdin, Licostrata, Lustra, Melanasa, Melanex, Melpaque, Melquin, Neostrata HQ, Phiaquin, Solaquin, Ultraquin, beta-Quinol, Hydroquinone, copper (1+) salt, Hydroquinone, lead (2+) salt (2:1), Hydroquinone, monocopper (2+) salt, 1,4-Dihydroxy-benzeen, 1,4-Dihydroxy-benzol,
1,4-Dihydroxybenzen, 1,4-Diidrobenzene, a-Hydroquinone, alpha-Hydroquinone, b-Quinol, Benzohydroquinone, Benzoquinol, Dihydroquinone, Dihydroxybenzene, Hydrochinon, Hydrochinone, Hydroquinol, Hydroquinole, Hydroquinone for synthesis, Hydroquinone GR, Hydroquinoue, Idrochinone, p-Dihydroxybenzene, P-Dioxobenzene, p-Dioxybenzene, P-Hydroxybenzene, Solaquin forte, Eldoquin forte, Stratus brand 1 OF hydroquinone, ICN brand 1 OF hydroquinone,
Plough brand 2 OF hydroquinone, Eldopaque forte, ICN brand 4 OF hydroquinone, Black and white, ICN brand 2 OF hydroquinone, ICN brand 3 OF hydroquinone,
Plough brand 1 OF hydroquinone, Stratus brand 2 OF hydroquinone, 1,4-Benzoquinol, 1,4-Phenylenediol, 1,4-p-Benzenediol, p-Dihydroquinone, p-Phenylenediol, p-Quinol, hydroquinone, 1,4-benzenediol, quinol, 1,4-dihydroxybenzene, p-benzenediol, 4-hydroxyphenol, p-hydroquinone, p-hydroxyphenol, p-dihydroxybenzene, benzoquinol, ?-Hydroquinone, ?-Quinol, P-Hydroquinone, Hydrochinon, Dihydroquinone, Hydroquinol, Benzoquinol, Hydrochinone, Hidroquinone, Hidroquin, Idrochinone, Para-Hydroquinone, Hydroquinole, Hidroquilaude, 1, 4-Dihydroxy-Benzeen, 1, 4-Diidrobenzene, Pyrogentistic Acid, Hydroquinoue, Ccris 714, Diak 5, 1,4-Benzene-2,3,5,6-d4-diol-d2, 1,2,4,5-Tetradeuterio-3,6-dideuteriooxybenzene, 1,4-Hydroquinone-d6, Hydroquinone-d6, Perdeuteriohydroquinone, 1,4-Benzenediol, 1,4-Dihydroxybenzene, 1,4-p-Benzenediol, 1,4-Phenylenediol, 4-Hydroxyphenol, Benzene-1,4-diol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, 4-Hydroxyphenol, benzene-1,4-diol, Benzene-1,4-diol, Eldoquin, hydroquinone, Hydroquinone, p-Benzenediol, p-Hydroquinone, p-hydroxyphenol, Quinol, Hydroquinone, p-Benzenediol, 1,4-Benzenediol, 1,4-Dihydroxybenzene, Benzene-1,4-diol, Quinol, 4-Hydroxyphenol, Quinol, Melanex, Idrochinone, HYDROQUINONE, HYDROCHINONE, Hydroquinone, HYDROXYQUINOL, Hydroxyquinone, 1,4-Benzenediol, benzene-1,4-diol, AKOS BBS-00004220, 1,4-Dihydroxybenzene, 1,4-Dihydroxy benzene, hydroquinone--1,4-benzenediol, 6,7-dihydroxy-2H-chromen-2-one, 1,4-Benzenediol, 1,4-Benzenediol (hydroquinone), 1,4-Dihydroxy-benzeen, 1,4-Dihydroxy-benzol, 1,4-Dihydroxybenzen, 1,4-Dihydroxybenzene, 1,4-Diidrobenzene, 4-Hydroxyphenol, Aida, Arctuvin, Benzene, p-dihydroxy-, Benzohydroquinone, Benzoquinol, Black & White Bleaching Cream, Black and White Bleaching Cream, Derma-Blanch, Diak 5, Dihydroquinone, Eldopacque, Eldopaque, Eldopaque forte, Eldoquin, Eldoquin forte, HE 5, Hidroquinone, Hydrochinon, Hydrochinone, Hydroquinol, Hydroquinole, Idrochinone, NCI-C55834, Phiaquin, Quinol, Solaquin forte, Tecquinol, Tenox HQ, Tequinol, UN 2662, USAF EK-356, p-Benzenediol, p-Dihydroquinone, p-Dihydroxybenzene, p-Dioxobenzene, p-Dioxybenzene, p-Hydroquinone, p-Hydroxyphenol, p-quinol, 1,4-Benzenediol, Quinol, 1,4-Dihydroxybenzene, HQ



Hydroquinone (quinol) is a metabolite found in the aging mouse brain.
Hydroquinone (quinol) is a Melanin Synthesis Inhibitor.
The mechanism of action of Hydroquinone (quinol) is as a Melanin Synthesis Inhibitor.


The physiologic effect of Hydroquinone (quinol) is by means of Depigmenting Activity.
Hydroquinone (quinol) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.


Hydroquinone (quinol) is an aromatic organic compound with the chemical formula C6H4(OH)2, also known as benzene-1,4-diol or quinol, which is a kind of phenol and also a derivative of benzene.
Hydroquinone (quinol) contains two hydroxyl groups bonded in a para position to the benzene ring.


Hydroquinone (quinol) is a granular white solid.
Hydroquinone (quinol)’s substituted derivatives are also known as hydroquinones.
Friedrich Wöhler coined the term “Hydroquinone (quinol)” in 1843.


Hydroquinone (quinol) is a skin-lightening agent used topically for the treatment of hyperpigmentation.
Hydroquinone (quinol) is an inhibitor and antioxidant, also is an intermediate in the synthesis of dyes, motor fuels, and oils.
Hydroquinone (quinol) is a white to off-white needle form crystal or freely flowable crystalline powder; Assay: Not less than 99.5%; Melting Point: 171 175.


Hydroquinone (quinol) is a skin-lightening agent.
Hydroquinone (quinol) bleaches the skin, which can be helpful when treating different forms of hyperpigmentation.
Historically, there’s been some back-and-forth on the safety of Hydroquinone (quinol).


In 1982, the U.S. Food and Drug Administration recognized Hydroquinone (quinol) as safe and effective.
Hydroquinone (quinol) is a white needle-like crystal with a molecular formula of C6H4(OH)2, a molecular weight of 110.11, a specific gravity of 1.332, a melting point of 172 degC, a boiling point of 286 degC, and a flash point of 165 degC.


Hydroquinone (quinol) is soluble in water, ethanol and ether, and slightly soluble in benzene.
Hydroquinone (quinol) is an aromatic organic compound.
Its chemical formula is C6H4(OH)2, Hydroquinone (quinol) is also known as benzene-1,4-diol or quinol.


Two hydroxyl groups bound to a benzene ring in the para position to form Hydroquinone (quinol).
Hydroquinone (quinol) is known as a melanin synthesis inhibitor and is a phenol derivative that has antioxidant properties.
Hydroquinone (quinol) has the appearance of granular solid white.


Hydroquinone (quinol) has several applications, which are primarily associated with its function as a reducing agent that is soluble in water.
Hydroquinone (quinol) is a major component of most black and white photographers for film and paper where, with the compound metol, it transforms silver halides into elemental silver.


Hydroquinone (quinol) is a white needle-like crystals.
Hydroquinone (quinol) is soluble in alcohol and ether, soluble in water, slightly soluble in benzene.
Hydroquinone (quinol) is visible light in the air easily turned to light red.


The aqueous solution oof Hydroquinone (quinol) can be oxidized to Brown in air.
Reactions with strong oxidants may occur.
Hydroquinone (quinol) is a weak acid.


Hydroquinone (quinol) reacts with most of the oxidizing agents and is converted to O-and p-benzoquinones.
Hydroquinone (quinol) has a, beta and gamma; Three crystal forms.
Type A is a triangular needle-like or diamond-like crystal, crystallized from water and stable.


Lu is a triangular crystal, crystallized from methanol, unstable.
The & gamma; Type is monoclinic crystal, which is obtained by sublimation method and is unstable.
All three crystals can be rubbed to emit fluorescence.
Hydroquinone (quinol), also benzene-1,4-diol or quinol, is an aromatic organic compound which is a type of phenol, having the chemical formula C6H4(OH)2.


Hydroquinone (quinol)'s chemical structure, shown in the table at right, has two hydroxyl groups bonded to a benzene ring in a para position.
Hydroquinone (quinol) is a white granular solid at room temperature and pressure.
Hydroquinone (quinol) is a quinone small molecule with efficacy as a topical preparation.



USES and APPLICATIONS of HYDROQUINONE (QUINOL):
Hydroquinone (quinol) is mainly used as a developer in photography.
Hydroquinone (quinol) and its alkylates are widely used as polymerization inhibitors added during the storage and transportation of monomers, the commonly used concentration is about 200ppm;2.


Hydroquinone (quinol) is used as antioxidant for rubber and gasoline.
Hydroquinone (quinol) is used as corrosion inhibitor, stabilizer and antioxidant in detergents, etc.
In the treatment field, Hydroquinone (quinol) is added to the hot water and cooling water of the closed-circuit heating and cooling system to inhibit corrosion of metals on the water side.


Hydroquinone (quinol) is also used as a deoxidizer for boiler water.
Hydroquinone (quinol) is added to the boiler water when it is preheated and deoxygenated to remove residual dissolved oxygen.
Hydroquinone (quinol) is a raw material for manufacturing anthraquinone dyes, azo dyes, medicines, etc.


Hydroquinone (quinol) is an intermediate of some herbicides, including quizalofop-ethyl, lactofen, haloxyfop, fenoxaprop-ethyl, fenthiaprop, fluazifop-butyl, etc.
Hydroquinone (quinol) is also used in the hair dye field of cosmetics.


Hydroquinone (quinol) is used as analytical reagent, reducing agent and developer for copper and gold.
Hydroquinone (quinol) is a major component of most black and white photographers for film and paper where, with the compound metol, it transforms silver halides into elemental silver.


There are several other applications for Hydroquinone (quinol)'s reducing power.
As a polymerization barrier, Hydroquinone (quinol) inhibits the polymerization of acrylic acid, methyl methacrylate, cyanoacrylate, and other monomers vulnerable to radical-initiated polymerization by using its antioxidant properties.


By serving as a free-radical scavenger, Hydroquinone (quinol) helps in improving the shelflife of light-sensitive resins such as preceramic polymers.
Hydroquinone (quinol) can form a diphenolate ion by losing a hydrogen cation from both hydroxyl groups.
Hydroquinone (quinol) has several applications, which are primarily associated with its function as a reducing agent that is soluble in water.


Hydroquinone (quinol) is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Hydroquinone (quinol) is used in the following products: photo-chemicals.


Other release to the environment of Hydroquinone (quinol) is likely to occur from: indoor use as reactive substance.
Hydroquinone (quinol) is used in the following products: photo-chemicals, coating products, inks and toners and polymers.
Hydroquinone (quinol) is used in the following areas: printing and recorded media reproduction, health services and scientific research and development.


Other release to the environment of Hydroquinone (quinol) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Hydroquinone (quinol) is used in the following products: photo-chemicals, water treatment chemicals and fuels.


Release to the environment of Hydroquinone (quinol) can occur from industrial use: formulation of mixtures and formulation in materials.
Hydroquinone (quinol) is used in the following products: photo-chemicals, polymers, coating products, inks and toners and water treatment chemicals.
Hydroquinone (quinol) has an industrial use resulting in manufacture of another substance (use of intermediates).


Hydroquinone (quinol) is used in the following areas: printing and recorded media reproduction and formulation of mixtures and/or re-packaging.
Release to the environment of Hydroquinone (quinol) can occur from industrial use: as processing aid, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.


Hydroquinone (quinol) is used as a photographic reducer and developer (except in color film), as a dye intermediate inhibitor, as a stabilizer in paints, varnishes, motor fuels and oils, as an antioxidant for fats and oils, as an inhibitor of polymerization, as a reagent in the determination of small quantities of phosphate and as a depigmentor.


Hydroquinone (quinol) is used inhibitor in acrylic monomers and polyester resins.
Hydroquinone (quinol) is used antioxidant in animal feed.
Hydroquinone (quinol) is used present in many bleaching creams.


Hydroquinone (quinol) is used occupational exposure in people working with antioxidants, bacteriostatics, furs, organic chemical synthesis, paints, plastics, rubber, drugs.
Hydroquinone (quinol) has a variety of uses principally associated with its action as a reducing agent which is soluble in water.


Hydroquinone (quinol) is a major component in most photographic developers where, with the compound Metol, it reduces silver halides to elemental silver.
In the field of water treatment, Hydroquinone (quinol) is added to the hot water and cooling water of the closed-circuit heating and cooling system, and the corrosion inhibition of the water side Metal energy is carried out.


Hydroquinone (quinol) is used as an oxygen scavenger for boiler water, and Hydroquinone (quinol) is added thereto to remove residual dissolved oxygen when the boiler water is preheated for oxygen removal.
Release to the environment of Hydroquinone (quinol) can occur from industrial use: manufacturing of the substance.


Hydroquinone (quinol) is used for the manufacture of: chemicals and plastic products.
In human medicine, Hydroquinone (quinol) is used as a topical application in skin whitening to reduce the color of skin as it does not have the same predisposition to cause dermatitis as Metol does.


The disodium diphenolate salt of Hydroquinone (quinol) is used as an alternating comonomer unit in the production of the polymer PEEK.
As a polymerization inhibitor, Hydroquinone (quinol) prevents polymerization of acrylic acid, methyl methacrylate, etc.
Hydroquinone (quinol) is also used as a raw material of herbicides, rubber antioxidants and dye stuffs.


Hydroquinone (quinol) has been found to reduce the viable cell number of some tumor cells.
Hydroquinone (quinol) is used as an intermediate in the production of dyes and other organic compounds.
Hydroquinone (quinol) also acts as a antioxidant and bleaching agent.


Hydroquinone (quinol) is used as imaging agent and dye, drug raw material
Hydroquinone (quinol) is used as a reducing agent.
Hydroquinone (quinol) is used for the preventive measures of methyl methacrylate.


Hydroquinone (quinol) is used in skin whitening.
Hydroquinone (quinol) is used helpful as a biomarker for benzene exposure.
Hydroquinone (quinol) is used by photographic developers


Hydroquinone (quinol) is used in the treatment of acne scars
Hydroquinone (quinol) is used in various cosmetic products



WHO USES HYDROQUINONE (QUINOL)?
Hydroquinone (quinol) is most commonly used in bleaching creams by patients aged 13 years and over with a dark skin type.
Hydroquinone (quinol) can be used, often in combination with other medications, to treat:
*Melasma
*Postinflammatory hyperpigmentation such as subsequent to acne
*Freckles and lentigines
*Poikiloderma of Civatte
*Drug-induced pigmentation due to chemotherapy agents
*Folliculitis barbae and pseudofolliculitis barbae
*Hydroquinone (quinol) may also be used as a pretreatment before fractional laser therapy or chemical peels.



WHAT SKIN CONDITIONS CAN BENEFIT FROM HYDROQUINONE (QUINOL)?
Hydroquinone (quinol) is used to treat skin conditions related to hyperpigmentation.
This includes:
*acne scars
*age spots
*freckles
*melasma
*post-inflammatory marks from psoriasis and eczema

Although Hydroquinone (quinol) can help fade red or brown spots that have lingered, it won’t help with active inflammation.
For example, Hydroquinone (quinol) can help minimize acne scarring, but it won’t have an effect on redness from active breakouts.



ALTERNATIVE PARENTS OF HYDROQUINONE (QUINOL):
*1-hydroxy-2-unsubstituted benzenoids
*Benzene and substituted derivatives
*Organooxygen compounds
*Hydrocarbon derivatives



SUBSTITUENTS OF HYDROQUINONE (QUINOL):
*Hydroquinone
*1-hydroxy-2-unsubstituted benzenoid
*Monocyclic benzene moiety
*Organic oxygen compound
*Hydrocarbon derivative
*Organooxygen compound
*Aromatic homomonocyclic compound



NATURAL OCCURRENCES OF HYDROQUINONE (QUINOL):
Hydroquinone (quinol) is one of the two primary reagents in the defensive glands of bombardier beetles, along with hydrogen peroxide (and perhaps other chemicals, depending on the species), which collect in a reservoir.

The reservoir opens through a muscle-controlled valve onto a thick-walled reaction chamber.
This chamber is lined with cells that secrete catalases and peroxidases.

When the contents of the reservoir are forced into the reaction chamber, the catalases and peroxidases rapidly break down the hydrogen peroxide and catalyze the oxidation of the Hydroquinone (quinol) into p-quinones.

These reactions release free oxygen and generate enough heat to bring the mixture to the boiling point and vaporize about a fifth of it, producing a hot spray from the beetle's abdomen.



HOW DOES HYDROQUINONE (QUINOL) WORK?
Hydroquinone (quinol) bleaches your skin by decreasing the number of melanocytes present.
Melanocytes make melanin, which is what produces your skin tone.

In cases of hyperpigmentation, more melanin is present due to an increase in melanocyte production.
By controlling these melanocytes, your skin will become more evenly toned over time.
It takes about four weeks on average for the ingredient to take effect.

It may take several months of consistent use before you see full results.
If you don’t see any improvements within three months of OTC use, talk to your dermatologist.
They may be able to recommend a prescription-strength formula better suited to your needs.



PROPERTIES OF HYDROQUINONE (QUINOL):
Hydroquinone (quinol) can undergo mild oxidation to convert to the compound parabenzoquinone, C6H4O2, often called p-quinone or simply quinone.
Reduction of quinone reverses this reaction back to Hydroquinone (quinol).

Some biochemical compounds in nature have this sort of Hydroquinone (quinol) or quinone section in their structures, such as Coenzyme Q, and can undergo similar redox interconversions.

The hydroxyl groups of Hydroquinone (quinol) are quite weakly acidic.
Hydroquinone (quinol) can lose an H+ from one of the hydroxyls to form a monophenolate ion or lose an H+ from both to form a diphenolate ion.



NOMENCLATURE OF HYDROQUINONE (QUINOL):
Hydroquinone (quinol) is the name recommended by the International Union of Pure and Applied Chemistry (IUPAC) in its 1993 Recommendations for the Nomenclature of Organic Chemistry



PREPARATION METHOD OF HYDROQUINONE (QUINOL):
Aniline is oxidized to p-benzoquinone with manganese dioxide in sulfuric acid medium and then reduced to Hydroquinone (quinol) with iron powder.



PHYSICAL AND CHEMICAL PROPERTIES OF HYDROQUINONE (QUINOL):
Physical and Chemical Properties
Character: White needle crystal.
melting point 172~175 ℃
boiling point 285~287 ℃
relative density 1.328g/cm3
flash point 165 ℃
solubility, ethanol and ether, benzene-soluble.



PRODUCTION OF HYDROQUINONE (QUINOL):
Industrial production of Hydroquinone (quinol) usually happens in two ways.
The most commonly used technique is identical to the cumene process in the reaction mechanism and, Hydroquinone (quinol) includes the dialkylation of benzene with propene to produce 1,4-diisopropyl benzene.

Hydroquinone (quinol) reacts with air to form bishydroperoxide, which has a similar structure compared to cumene hydroperoxide and, it rearranges in acid to form acetone and Hydroquinone (quinol).

The second method includes the hydroxylation of phenol over a catalyst.
The conversion process uses hydrogen peroxide and provides a combination of Hydroquinone (quinol) and catechol (benzene-1,2-diol):

C6H5OH+H2O2⟶C6H4(OH)2+H2O
Some other methods for producing Hydroquinone (quinol) are:

Oxidation of various phenols can also produce Hydroquinone (quinol) and its derivatives.
Examples of such method are Elbs persulfate oxidation and Dakin oxidation.
French chemists Pelletier and Caventou first obtained Hydroquinone (quinol) in 1820 through the dry distillation process of quinic acid.



PROPERTIES OF HYDROQUINONE (QUINOL):
*Formula of Hydroquinone (quinol) is C6H6O2.
*The Molecular Weight of Hydroquinone (quinol) is 110.11 g/mol.
*The Boiling Point of Hydroquinone (quinol) is 287°C
*Also, the Melting Point of Hydroquinone (quinol) is 172°C.
*The Density of Hydroquinone (quinol) is 1.3gcm−3.
*Hydroquinone (quinol) is soluble in water.
*Hydroquinone (quinol) has a white-solid appearance.



PHYSICAL and CHEMICAL PROPERTIES of HYDROQUINONE (QUINOL):
CAS number: 123-31-9
EC index number: 604-005-00-4
EC number: 204-617-8
Hill Formula: C₆H₆O₂
Chemical formula: C₆H₄(OH)₂
Molar Mass: 110.11 g/mol
HS Code: 2907 22 00
Boiling point: 287 °C (1013 hPa)
Density: 1.332 g/cm3 (15 °C)
Flash point: 165 °C
Ignition temperature: 515 °C
Melting Point: 171 °C (decomposition)
pH value: 3.7 (70 g/l, H₂O)
Vapor pressure: 1 hPa (132 °C)
Bulk density: 600 kg/m3
Solubility: 70 g/l

Chemical Name: HYDROQUINONE
CAS No: 123-31-9
Main Material: HYDROQUINONE
Storage: Other
Boiling point: 287 °C (549 F; 560 K)
HS Code: 29072200
Grade: Industrial Grade
Taste: Other
Molecular Weight: 110.112 g/mol
Molecular Formula: 110.112 g/mol
Classification: Other
Smell: Other
Other Names: Quinol

Density: 1.3 g/cm3, solid Kilogram per litre (kg/L)
Melting Point: 172 °C (342 F; 445 K)
Solubility: 5.9 g/100 mL (15 °C)
Structural Formula: C6H6O2
Form: Solid
CAS: 123-31-9
EINECS: 204-617-8
InChI: InChI=1/C9H6O4/c10-6-3-5-1-2-9(12)13-8(5)4-7(6)11/h1-4,10-11H
InChIKey: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
Molecular Formula: C6H6O2
Molar Mass: 110.11
Density: 1.32
Melting Point: 172-175°C (lit.)
Boiling Point: 285°C (lit.)
Flash Point: 165 °C

Water Solubility: 70 g/L (20 ºC)
Solubility: H2O: 50 mg/mL, clear
Vapor Pressure: 1 mm Hg (132 °C)
Vapor Density: 3.81 (vs air)
Appearance: Needle-Like Crystals or Crystalline Powder
Color: White to off-white
Merck: 14,4808
BRN: 605970
pKa: 10.35 (at 20°C)
Storage Condition: Store below +30°C.
Stability: Stable.
Sensitive: Air & Light Sensitive
Refractive Index: 1.6320
Molecular Weight: 110.11
Appearance Form: crystalline

Color: colorless
Odor: No data available
Odor Threshold: No data available
pH: 3,7 at 70 g/l
Melting point/freezing point:
Melting point/range: 172 - 175 °C - lit.
Initial boiling point and boiling range: 285 °C - lit.
Flash point: 165 °C at ca.1.013 hPa
Evaporation rate: No data available
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 1 hPa at 132 °C
Vapor density: 3,80 - (Air = 1.0)

Density: 1,332 g/cm3 at 15 °C
Relative density: No data available
Water solubility 72 g/l at 25 °C - completely soluble
Partition coefficient: n-octanol/water
log Pow: 0,59 - Bioaccumulation is not expected.
Autoignition temperature: 515,56 °C at 1.013 hPa
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:

Relative vapor density: 3,80 - (Air = 1.0)
Water Solubility: 95.5 g/L
logP: 0.71
logP: 1.37
logS: -0.06
pKa (Strongest Acidic): 9.68
pKa (Strongest Basic): -5.9
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 2
Polar Surface Area: 40.46 Ų
Rotatable Bond Count: 0
Refractivity: 30.02 m³·mol⁻¹
Polarizability: 10.75 ų
Number of Rings: 1

Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
IUPAC Name: benzene-1,4-diol
Traditional IUPAC Name: α-hydroquinone
Formula: C6H6O2
InChI: InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
InChI Key: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
Molecular weight: 110.1106
Exact mass: 110.036779436
SMILES: OC1=CC=C(O)C=C1
Chemical Formula: C6H6O2
Average Molecular Weight: 110.1106
Monoisotopic Molecular Weight: 110.036779436

IUPAC Name: benzene-1,4-diol
Traditional Name: α-hydroquinone
CAS Registry Number: 123-31-9
SMILES: OC1=CC=C(O)C=C1
InChI Identifier: InChI=1S/C6H6O2/c7-5-1-2-6(8)4-3-5/h1-4,7-8H
InChI Key: QIGBRXMKCJKVMJ-UHFFFAOYSA-N
Melting Point: 170.0°C to 174.0°C
Color: White
Density: 1.32
Boiling Point: 285.0°C to 287.0°C
Flash Point: 165°C
Infrared Spectrum: Authentic
Assay Percent Range: 98.5% min. (HPLC)
Beilstein: 06, 836

Fieser: 05,341; 14,249
Merck Index: 15, 4845
Solubility Information: Solubility in water: 70g/L in water (20°C).
Other solubilities: soluble in alcohol and ether,slightly soluble in benzene,
readily soluble in ethanol,acetone and methanol
Formula Weight: 110.11
Percent Purity: 99%
Physical Form: Needle-like Crystals or Crystalline Powder
Chemical Name or Material: Hydroquinone, 99%
C6H6O2: Hydroquinone
Molecular Weight/ Molar Mass: 110.11 g/mol
Density: 1.3 g cm−3
Boiling Point: 287 °C
Melting Point: 172 °C



FIRST AID MEASURES of HYDROQUINONE (QUINOL):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROQUINONE (QUINOL):
-Personal precautions, protective equipment and emergency procedures:
Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROQUINONE (QUINOL):
-Extinguishing media:
*Suitable extinguishing media:
Water Foam Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROQUINONE (QUINOL):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use safety goggles.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Use protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROQUINONE (QUINOL):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
*Hygiene measures:
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROQUINONE (QUINOL):
-Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .

HYDROQUINONE MONOMETHYL ETHER
Hydroquınone Monomethyl Ether, 99% is a common active ingredient in topical drugs used for skin depigmentation.
Hydroquınone Monomethyl Ether is a performance chemical and is an organic compound and synthetic derivative of hydroquinone.
Hydroquınone Monomethyl Ether is commercially manufactured by the hydroxylation of anisole or by free radical reaction between p-benzoquinone and methanol.

CAS: 150-76-5
MF: C7H8O2
MW: 124.14
EINECS: 205-769-8

Synonyms
Eastman HQMME;ethermonomethyliqued’hydroquinone;Hqmme;Hydroquinone methyl ether;hydroquinonemethylether;Leucobasal;Leucodine b;leucodineb;4-Methoxyphenol;Mequinol;150-76-5;4-Hydroxyanisole;p-Hydroxyanisole;p-Methoxyphenol;Phenol, 4-methoxy-;HYDROQUINONE MONOMETHYL ETHER;Leucobasal;MEHQ;Leucodine B;Mechinolum;P-Guaiacol;Novo-Dermoquinona;Hydroquinone methyl ether;HQMME;p-Hydroxymethoxybenzene;para-methoxyphenol;1-Hydroxy-4-methoxybenzene;Monomethyl ether hydroquinone;PMF (antioxidant)
;Phenol, p-methoxy-;USAF AN-7;4-Methoxy-phenol;Mechinolo;Mequinolum;Mono methyl ether hydroquinone;NSC 4960;CCRIS 5531;BMS 181158;BMS-181158;DTXSID4020828;HSDB 4258;UNII-6HT8U7K3AM;NSC-4960;EINECS 205-769-8;6HT8U7K3AM;MFCD00002332;AI3-00841;NSC4960;DTXCID60828;SOLAGE COMPONENT MEQUINOL;CHEBI:69441;EC 205-769-8;Mequinol (INN);MEQUINOL COMPONENT OF SOLAGE;NCGC00091390-02;MEQUINOL [INN];MEQUINOL (MART.);MEQUINOL [MART.];Mechinolo [DCIT];Mequinolum [INN-Latin];CAS-150-76-5;Mequinol [USAN:INN:DCF];4methoxyphenol;paramethoxyphenol;p- methoxyphenol;p-methoxy phenol;p-methoxy-phenol;4-methoxy phenol;Eastman HQMME;para-hydroxyanisole;4-(methoxy)phenol;4HA;4KS;para- hydroxyanisole;4-(methyloxy)phenol;HQME;hydroquinone methylether;MEQUINOL [HSDB];MEQUINOL [USAN];Mequinol (USAN/INN);Mequinol, INN, USAN;MEQUINOL [VANDF];PHENOL,4-METHOXY;hydroxyquinone methyl ether;hydroquinone monomethylether;CHEMBL544;MEQUINOL [WHO-DD];NCIMech_000709

Mequinol, Hydroquınone Monomethyl Ether or 4-methoxyphenol, is an organic compound with the formula CH3OC6H4OH.
Hydroquınone Monomethyl Ether is a phenol with a methoxy group in the para position.
A colorless solid, Hydroquınone Monomethyl Ether is used in dermatology and organic chemistry.
Mequinol, Hydroquınone Monomethyl Ether or 4-methoxyphenol, is an organic compound with the formula CH3OC6H4OH.
Hydroquınone Monomethyl Ether is a phenol with a methoxy group in the para position.
A colorless solid, Hydroquınone Monomethyl Ether is used in dermatology and organic chemistry.
Hydroquınone Monomethyl Ether is used as a Polymerization inhibitor in the manufacturing of Acrylic acids, primarily involved in the manufacturing of acrylic fibres, paints and inks, adhesives, and super absorbent polymers.
Hydroquınone Monomethyl Ether is also used in the manufacturing of Methacrylic, other Acrylates, Vinyl Acetate Monomer (VAM), Styrene Monomer and in Unsaturated Polyesters, etc.

Hydroquınone Monomethyl Ether Chemical Properties
Melting point: 56 °C
Boiling point: 243 °C(lit.)
Density: 1,55 g/cm3
Vapor density: 4.3 (vs air)
Vapor pressure: Refractive index: 1.5286 (estimate)
Fp: >230 °F
Storage temp.: Store below +30°C.
Solubility: Soluble in acetone, ethyl acetate, ethanol, ether, benzene and carbon tetrachloride.
Form: Liquid
pka: 10.21(at 25℃)
Color: Clear colorless to pale yellow
Odor: at 1.00?%?in?dipropylene glycol. phenolic
PH: 5.1 (30g/l, H2O, 20℃)
Odor Threshold: 0.0027ppm
Water Solubility: 40 g/L (25 ºC)
BRN: 507924
Exposure limits ACGIH: TWA 5 mg/m3
NIOSH: TWA 5 mg/m3
Stability: Stable. Combustible. Incompatible with halogens, oxidizing agents.
InChIKey: NWVVVBRKAWDGAB-UHFFFAOYSA-N
LogP: 1.3 at 20℃
CAS DataBase Reference: 150-76-5(CAS DataBase Reference)
NIST Chemistry Reference: Hydroquınone Monomethyl Ether (150-76-5)
EPA Substance Registry System: Hydroquınone Monomethyl Ether (150-76-5)

Uses
Hydroquınone Monomethyl Ether is an active ingredient and used in dermatology.
Hydroquınone Monomethyl Ether is employed as a pharmaceutical drug in skin depigmentation.
Hydroquınone Monomethyl Ether is used as polymerization inhibitors.
For example, in the radical polymerization of acryaltes and styrene monomers.
Hydroquınone Monomethyl Ether is also used as an intermediate in the preparationagrochemicals, liquid crystals.
Hydroquınone Monomethyl Ether acts as a stabilizer for the formulation of inks, toners and adhesives.
Hydroquınone Monomethyl Ether is mainly used as an additive for textile and leather industries.
HYDROQUINONE SULFATE
Hydroquinone sulfate has a role as a marine xenobiotic metabolite.
Hydroquinone sulfate is a conjugate acid of a quinol sulfate(1-).


CAS Number: 17438-29-8
Chemical Formula: C6H6O5S
Molecular Formula: C6H5O5S-



SYNONYMS:
hydroquinone sulfate, quinol sulfate(1-), 4-hydroxyphenyl sulfate, (4-hydroxyphenyl) sulfate, 1,4-benzenediol monosulfate, CHEBI:133073, 1,4-benzenediol monosulfate 4-hydroxyphenyl sulfate hydroquinone monosulfate hydroquinone sulfate quinol monosulfate quinol sulfate, quinol sulfate 1,4-Benzenediol, 1-(hydrogen sulfate), Hydrochinonmonoschwefelsaeure, Schwefelsaeure-[4-hydroxy-phenylester], sulfuric acid mono-(4-hydroxy-phenyl ester), O-Sulfo-hydrochinon, Schwefelsaeure-mono-(4-hydroxy-phenylester), (4-Hydroxy-phenyl)-hydrogensulfate, 4-Oxy-phenylschwefelsaeure, 1,4-Benzenediol, 1-(hydrogen sulfate), Hydroquinone, mono(hydrogen sulfate), 1,4-Benzenediol, mono(hydrogen sulfate), Hydroquinone, hydrogen sulfate, Quinol sulfate, Hydroquinone monosulfonate, Quinol monosulfate, Hydroquinone monosulfate, p-Hydroxyphenyl sulfate, (4-Hydroxyphenyl)oxidanesulfonic acid, 1,4-Benzenediol,mono(hydrogen sulfate) (9CI), Hydroquinone, hydrogen sulfate (6CI), Hydroquinone, mono(hydrogen sulfate) (8CI), Hydroquinone monosulfate, Hydroquinone monosulfonate, Quinol monosulfate, Quinol sulfate, p-Hydroxyphenylsulfate, quinol sulfate, 4-Hydroxyphenyl hydrogen sulfate, 1,4-Benzenediol, 1-(hydrogen sulfate), Hydroquinone monosulfonate, p-Hydroxyphenyl sulfate, Quinol Monosulfate, 1,4-Benzenediol,1-(hydrogen sulfate), Hydroquinone,mono(hydrogen sulfate), 1,4-Benzenediol,mono(hydrogen sulfate), Hydroquinone,hydrogen sulfate, Quinol sulfate, Hydroquinone monosulfonate, Quinol monosulfate, Hydroquinone monosulfate, p-Hydroxyphenyl sulfate, (4-Hydroxyphenyl)oxidanesulfonic acid, hydroquinone mono(hydrogen sulfate)



Hydroquinone sulfate is an organosulfonate oxoanion that is the conjugate base of quinol sulfate, obtained by deprotonation of the sulfo group; major species at pH 7.3.
Hydroquinone sulfate has a role as a marine xenobiotic metabolite.


Hydroquinone sulfate is a conjugate base of a quinol sulfate.
Hydroquinone sulfate is an aryl sulfate that is quinol (hydroquinone) with one of the two hydroxy groups substituted by a sulfo group.
Hydroquinone sulfate is an aryl sulfate that is quinol (hydroquinone) with one of the two hydroxy groups substituted by a sulfo group.


Hydroquinone sulfate has a role as a human xenobiotic metabolite and a marine xenobiotic metabolite.
Hydroquinone sulfate is an aryl sulfate and a member of phenols.
Hydroquinone sulfate is functionally related to a hydroquinone.


Hydroquinone sulfate is a conjugate acid of a quinol sulfate(1-).
Hydroquinone sulfate is an organosulfonate oxoanion that is the conjugate base of quinol sulfate, obtained by deprotonation of the sulfo group; major species at pH 7.3.


The exact mass of Hydroquinone sulfate is unknown and the complexity rating of the compound is unknown.
Hydroquinone sulfate's Medical Subject Headings (MeSH) category is Chemicals and Drugs Category - Organic Chemicals - Hydrocarbons - Hydrocarbons, Cyclic - Hydrocarbons, Aromatic - Benzene Derivatives - Phenols - Hydroquinones - Supplementary Records.


Hydroquinone sulfate belongs to the ontological category of phenols in the ChEBI Ontology tree.
Hydroquinone sulfate is a chemical compound that has been widely used in scientific research due to its unique properties.
Hydroquinone sulfate has been studied extensively for its potential applications in various fields, including medicine, agriculture, and environmental science.



USES and APPLICATIONS of HYDROQUINONE SULFATE:
-Scientific Research Applications
*Antimicrobial Activity of Hydroquinone sulfate
Quinolines, including Hydroquinone sulfate derivatives, have demonstrated notable antimicrobial properties.

A study investigated the antimicrobial activities of various quinolines against gram-positive and gram-negative bacteria, including strains of meticillin-resistant Staphylococcus aureus (MRSA).
Some quinolines showed significant activity, comparable to established antibiotics like vancomycin.


*Cancer Research
Quinolines have been identified as promising compounds in cancer research due to their potent anti-cancer properties.
One study reviewed quinoline compounds and their analogs, focusing on their anticancer activities, mechanisms of action, and potential as cancer drug targets.


*Bioactive Compounds Discovery
Sesquiterpene quinols, a class closely related to Hydroquinone sulfate, have been isolated from marine sponges, showing potential in CDK4/cyclin D1 complexation inhibition, a mechanism relevant in cancer treatment.


*Anticoagulant Research
A study discovered new sulfated quinoline alkaloids with potential anticoagulant and antiplatelet activities.
These findings suggest that quinoline derivatives could be useful in the development of new anticoagulants.


*Antioxidant Activity Evaluation of Hydroquinone sulfate:
Quinolinic acid, related to Hydroquinone sulfate, was used as an iron chelating agent in a study to determine the antioxidant activity of plant extracts.
This research demonstrated the potential of quinoline derivatives in evaluating antioxidant properties.


*Antibacterial Resistance of Hydroquinone sulfate:
The mechanisms of resistance to quinolines, including alterations in quinol targets and decreased accumulation, have been extensively studied.
Understanding these resistance mechanisms is crucial for developing effective antibacterial agents.



PHYSICAL and CHEMICAL PROPERTIES of HYDROQUINONE SULFATE:
Molecular Weight: 189.17 g/mol
XLogP3-AA: 0.5
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 1
Exact Mass: 188.98576943 g/mol
Monoisotopic Mass: 188.98576943 g/mol
Topological Polar Surface Area: 95Ų
Heavy Atom Count: 12
Formal Charge: -1
Complexity: 208
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Name: Hydroquinone sulfate
Systematic Name: Not Available
Synonyms: Not Available
CAS Number: Not Available
Average Mass: 190.17
Monoisotopic Mass: 189.993594467
Chemical Formula: C6H6O5S
IUPAC Name: (4-hydroxyphenyl)oxidanesulfonic acid

InChI Key: FPXPQMOQWJZYBL-UHFFFAOYSA-N
InChI Identifier: InChI=1S/C6H6O5S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4,7H,(H,8,9,10)
SMILES: OC1=CC=C(OS(O)(=O)=O)C=C1
Solubility (ALOGPS): 5.86e+00 g/l
LogS (ALOGPS): -1.51
LogP (ALOGPS): -0.88
Hydrogen Acceptors: 4
Hydrogen Donors: 2
Rotatable Bond Count: 2
Polar Surface Area: 83.83
Refractivity: 40.0116
Polarizability: 15.879416904230789
Formal Charge: 0

Physiological Charge: -1
pKa (strongest basic): -5.953792236729969
pKa (strongest acidic): -2.4583959376494575
Number of Rings: 1
Rule of Five: Yes
Bioavailability: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Density: 1.669±0.06 g/cm³ (Predicted)
pKa: -3.67±0.18 (Predicted)
CAS Number: 17438-29-8
Molecular Formula: C6H6O5S

Molecular Weight: 190.17
EINECS: Not Available
MOL File: 17438-29-8.mol
CAS: 17438-29-8
MF: C6H6O5S
MW: 190.17
EINECS: Not Available
Mol File: 17438-29-8.mol
Product Name: Quinol sulfate
IUPAC Name: (4-hydroxyphenyl) hydrogen sulfate
Molecular Formula: C6H6O5S
Molecular Weight: 190.18 g/mol
InChI: InChI=1S/C6H6O5S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4,7H,(H,8,9,10)
InChI Key: FPXPQMOQWJZYBL-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1O)OS(=O)(=O)O

Synonyms: hydroquinone mono(hydrogen sulfate), quinol sulfate
Canonical SMILES: C1=CC(=CC=C1O)OS(=O)(=O)O
Chemical Name: quinol sulfate
CAS Number: 17438-29-8
Molecular Formula: C6H6O5S
Molecular Weight: 190.17400
Appearance: NA
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA
InChI: InChI=1S/C6H6O5S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4,7H,(H,8,9,10)
InChIKey: FPXPQMOQWJZYBL-UHFFFAOYSA-N
SMILES: O(S(=O)(=O)O)C1=CC=C(O)C=C1
Canonical SMILES: O=S(=O)(O)OC1=CC=C(O)C=C1

Synonyms: (4-hydroxyphenyl) hydrogen sulfate
CAS No.: 17438-29-8
MDL No.: MFCD19705194
Molecular Formula: C6H6O5S
Molecular Weight: 190.17
Storage: 2-8 °C
Purity: 95.0%
CAS RN: 17438-29-8
Product Name: Quinol sulfate
Molecular Formula: C6H6O5S
Molecular Weight: 190.18 g/mol
IUPAC Name: (4-hydroxyphenyl) hydrogen sulfate
InChI: InChI=1S/C6H6O5S/c7-5-1-3-6(4-2-5)11-12(8,9)10/h1-4,7H,(H,8,9,10)
InChI Key: FPXPQMOQWJZYBL-UHFFFAOYSA-N
SMILES: C1=CC(=CC=C1O)OS(=O)(=O)O

Canonical SMILES: C1=CC(=CC=C1O)OS(=O)(=O)O
Other CAS RN: 61162-95-6, 17438-29-8
Related CAS: 61162-95-6 (sulfate, MF unknown)
Molecular Weight:190.18
XLogP3:0.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:189.99359446
Monoisotopic Mass:189.99359446
Topological Polar Surface Area:92.2
Heavy Atom Count:12
Complexity:221
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes



FIRST AID MEASURES of HYDROQUINONE SULFATE:
-General Advice:
If symptoms persist, call a physician.
*Eye Contact:
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Get medical attention.
*Skin Contact:
Wash off immediately with plenty of water for at least 15 minutes.
Get medical attention.
*Ingestion:
Clean mouth with water and drink afterwards plenty of water.
Get medical attention.
*Inhalation:
Remove to fresh air.
If breathing is difficult, give oxygen.
Get medical attention.
-Self-Protection of the First Aider:
Use personal protective equipment as required.
-Notes to Physician:
Treat symptomatically.



ACCIDENTAL RELEASE MEASURES of HYDROQUINONE SULFATE:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment as required.
-Environmental precautions:
Prevent product from entering drains.
Collect spillage.
-Methods and material for containment and cleaning up:
Sweep up and shovel into suitable containers for disposal.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HYDROQUINONE SULFATE:
-Extinguishing media:
*Suitable Extinguishing Media:
Water spray, carbon dioxide (CO2), dry chemical, alcohol-resistant foam.
*Extinguishing media which must not be used for safety reasons:
No information available.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROQUINONE SULFATE:
-Exposure controls:
--Personal protective equipment:
*Eye Protection:
Tight sealing safety goggles Goggles.
*Hand Protection:
Protective gloves



HANDLING and STORAGE of HYDROQUINONE SULFATE:
-Precautions for safe handling:
Wear personal protective equipment/face protection.
Ensure adequate ventilation.
*Hygiene Measures:
Handle in accordance with good industrial hygiene and safety practice.
-Conditions for safe storage, including any incompatibilities:
Keep containers tightly closed in a dry, cool and well-ventilated place.



STABILITY and REACTIVITY of HYDROQUINONE SULFATE:
-Reactivity:
None known, based on information available
-Chemical stability:
Stable under normal conditions.


HYDROVITON PLUS 2290
Hydroviton Plus 2290 is easy to formulate, water-soluble compound.
Hydroviton Plus 2290 is an active ingredient that offers immediate and long-term hydration to the skin.


CAS Number: 7647-14-5, 69-79-4, 50-99-7, 9067-32-7, 97-59-6, 28874-51-3, 77-92-9, 5949-29-1, 57-48-7, 56-81-5, 57-13-6, 5343-92-0
INCI Name: Water (Aqua) (and) Pentylene Glycol (and) Glycerin (and) Fructose (and) Urea (and) Citric Acid (and) Sodium Hydroxide (and) Maltose (and) Sodium PCA (and) Sodium Chloride (and) Sodium Lactate (and) Trehalose (and) Allantoin (and) Sodium Hyaluronate (and) Glucose



Hydroviton Plus 2290 is a smart blend of small hygroscopic molecules that penetrate the skin and restore the NMF.
Hydroviton Plus 2290 is an instant, long lasting moisturizer proven to deliver intense hair hydration and 72h skin moisturization.
Hydroviton Plus 2290 is a smart blend of small hygroscopic molecules that penetrate the skin and restore the NMF.


Hydroviton Plus 2290 is an instant, long lasting moisturizer proven to deliver intense hair hydration and 72h skin moisturization.
Hydroviton Plus 2290 is a colorless, clear liquid used in moisturizing and hair care products.
Hydroviton Plus 2290 is a colorless to light yellow clear liquid, odorless.


Hydroviton Plus 2290 is easy to formulate, water-soluble compound.
Hydroviton Plus 2290 is an active ingredient that offers immediate and long-term hydration to the skin.


Hydroviton Plus 2290 is a smart blend of small hygroscopic molecules that penetrate the skin and restore the NMF.
Hydroviton Plus 2290 is an instant, long lasting moisturizer proven to deliver intense hair hydration and 72h skin moisturization.



USES and APPLICATIONS of HYDROVITON PLUS 2290:
Hydroviton Plus 2290 is an instant, long lasting moisturizer proven to deliver intense hair hydration and 72h skin moisturization.
Hydroviton Plus 2290 acts as a moisturizing agent. Offers instant, long lasting and intense effects to hair and skin (48 hours).
Hydroviton Plus 2290 is nature-inspired biomimetic synergistic complex with hyaluronic acid.


Hydroviton Plus 2290 is skin friendly active: contains sugars & moisturizers naturally occurring in the skin.
Hydroviton Plus 2290 provides short-term and long-lasting moisturization for maximum skin hydration
72 hours of intense and continuous hydration.


Hydroviton Plus 2290 maintains and restores the water content in the epidermis by moisturizing and providing suppleness to the skin.
In addition, Hydroviton Plus 2290 improves the management of the skin's own moisture reserves.


Hydroviton Plus 2290 increases water content of hair by 51%.
Hydroviton Plus 2290 and Hydroviton Plus – clinically proven to increase skin hydration by 17% for up to 48 hours and by 10% for up to 72 hours after a single application.


In particular, Hydroviton Plus 2290 is a biomimetic complex which is able to penetrate and remain in the skin for a long time.
Based on a mixture of natural ingredients, Hydroviton Plus 2290 works through dual hydration methods combining small hygroscopic molecules (whose role is to restore the skin's ability to retain water) and polymers (which create a film on the skin's surface that protects against possible dehydration) ).


Hydroviton Plus 2290 is a long-lasting moisturizing complex, saturates the skin with highly hygroscopic substances that retain and bind water in the epidermis; plant ceramides - restore and supplement the natural lipids of the intercellular cement of the stratum corneum.


By sealing the cement, they prevent water from escaping from the epidermis (TEWL), moisturize and smooth; extracts from rosemary leaves, willow bark and birch - have astringent, bacteriostatic and smoothing properties.
They improve skin color and normalize the secretory activity of sebaceous glands; allantoin – moisturizes and soothes irritations.



HYDROVITON PLUS 2290 CONSISTS OF:
- Natural Moisturizing Factors (such as sodium lactate, lactic acid, urea, allantoin, sodium PCA, glycerin, Hydrolite 5).
Thanks to their hygroscopic properties, they retain moisture within the skin and help maintain skin elasticity.

- Natural Hydrating Sugars (such as D-Trehalose, Maltose & Fructose).
They offer excellent moisturizing benefits and thanks to their low molecular weight they are able to penetrate the skin.

- Hyaluronic acid
Water-soluble, Hydroviton Plus 2290 is used at room temperature and is preferably incorporated at the end of the production process.
1% to 4% is recommended for applications such as face and body moisturizers, baby care products, hand and foot products, after sun products , etc.

Clinical studies show that Hydroviton Plus 2290 prevents dehydration of the skin, increases its ability to retain water and prevents premature aging of the skin.

In addition, in just 2 hours of application Hydroviton Plus 2290 hydrates the surface layers and offers up to 72 hours of comfort to the skin with a +10% increase in hydration.



HOW TO USE HYDROVITON PLUS 2290:
Hydroviton Plus 2290 is an intensive moisturiser that uplifts your skin with up to 72 hours hydration.



CLAIMS OF HYDROVITON PLUS 2290:
*Moisturizing Agents
*long-lasting
*moisturizing



BENEFITS OF HYDROVITON PLUS 2290:
• Hydroviton Plus 2290 increases skin hydration
• Hydroviton Plus 2290 lifts and tightens the appearance of skin
• Hydroviton Plus 2290 improves elasticity
• Hydroviton Plus 2290 boosts radiance
• Hydroviton Plus 2290 smooths the appearance of lines and wrinkles



INGEDIENTS OF HYDROVITON PLUS 2290:
• Hydroviton Plus 2290: An instant, long lasting moisturiser proven to deliver 48-hour skin moisturisation.
• Hydroviton Plus 2290: Increases skin hydration by 17% for up to 48 hours and by 10% for up to 72 hours.



PHYSICAL and CHEMICAL PROPERTIES of HYDROVITON PLUS 2290:
CAS Number: 7647-14-5, 69-79-4, 50-99-7, 9067-32-7, 97-59-6, 28874-51-3, 77-92-9, 5949-29-1, 57-48-7, 56-81-5, 57-13-6, 5343-92-0
INCI Name: Water (Aqua) (and) Pentylene Glycol (and) Glycerin (and) Fructose (and) Urea (and) Citric Acid (and) Sodium Hydroxide (and) Maltose (and) Sodium PCA (and) Sodium Chloride (and) Sodium Lactate (and) Trehalose (and) Allantoin (and) Sodium Hyaluronate (and) Glucose



FIRST AID MEASURES of HYDROVITON PLUS 2290:
-Description of first-aid measures
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with
water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed.
No data available



ACCIDENTAL RELEASE MEASURES of HYDROVITON PLUS 2290:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROVITON PLUS 2290:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROVITON PLUS 2290:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROVITON PLUS 2290:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROVITON PLUS 2290:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available


HYDROVITON24
Hydroviton 24 is an advanced 24 hour moisturizing complex comprised of a synergistic blend of natural moisturizing factors.
Hydroviton 24 is non occlusive, so it allows skin to breathe and can be easily formulated into products.
Hydroviton 24 is also non-animal derived, preservative free, cost effective, light in color, and odorless in your formulation.

CAS: 50-70-4
MF: C6H14O6
MW: 182.17
EINECS: 200-061-5

Synonyms
Esasorb;Glucitol, D-;Gulitol;Hexahydric alcohol;Hydex 100 gran.206;Karion, sionit;L-gulitol;Liponic 70-NC

Hydroviton 24 acts as a moisturizer.
Hydroviton 24 is a synergistic blend of NMFs, humectants, hygroscopic substances, skin rejuvenators, skin protectants and penetration enhancer.
Hydroviton 24 is a non-animal derived and preservative free product.
Hydroviton 24 is dermatologically and toxicologically safe and can be easily formulated into products.
Hydroviton 24 provides 24 hours moisturizing effects demonstrated in vivo test.
Hydroviton 24 is used in skin care formulations.
Hydroviton 24 is China compliant.
A polyhydric alcohol, CH2OH(CHOH)4CH2OH, derived from glucose; Hydroviton 24 is isomeric with mannitol.
Hydroviton 24 is found in rose hips and rowan berries and is manufactured by the catalytic reduction of glucose with hydrogen.
Hydroviton 24 is used as a sweetener (in diabetic foods) and in the manufacture of vitamin C and various cosmetics, foodstuffs, and medicines.

Use
Hydroviton 24 is a liquid moisturizing factor and consists of a mixture of amino acid, sodium lactate, urea, allantoin and polyvalent alcohols.
Hydroviton 24 improves the natural moisturizing factors (NMF) in the corneocytes of the stratum corneum for 24 h moisturized skin.
Hydroviton 24 is a non occlusive ingredient that allows skin to breathe.

Hydroviton 24 Chemical Properties
Melting point: 98-100 °C (lit.)
alpha: 4 º (per eur. pharm.)
Boiling point: bp760 105°
Density: 1.28 g/mL at 25 °C
Vapor density: Vapor pressure: Refractive index: n20/D 1.46
FEMA: 3029 | D-SORBITOL
Fp: >100°C
Storage temp.: room temp
Solubility: Very soluble in water, slightly soluble in ethanol
Form: liquid
pka: pKa (17.5°): 13.6
Color: White
Specific Gravity: 1.28
Odor: Odorless
PH Range: 5 - 7 at 182 g/l at 25 °C
PH: 5.0-7.0 (25℃, 1M in H2O)
Optical activity: [α]20/D 1.5±0.3°, c = 10% in H2O
Odor Type: caramellic
Water Solubility: SOLUBLE
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.04
λ: 280 nm Amax: 0.045
Merck: 14,8725
BRN: 1721899
Dielectric constant: 33.5(27℃)
Stability: Stable. Avoid strong oxidizing agents. Protect from moisture.
InChIKey: FBPFZTCFMRRESA-JGWLITMVSA-N
LogP: -4.67
CAS DataBase Reference: 50-70-4(CAS DataBase Reference)
NIST Chemistry Reference: Hydroviton 24 (50-70-4)
EPA Substance Registry System: Hydroviton 24 (50-70-4)

Uses
Hydroviton 24 is a humectant that is a polyol (polyhydric alcohol) produced by hydrogenation of glucose with good solubility in water and poor solubility in oil.
Hydroviton 24 is approximately 60% as sweet as sugar, and has a caloric value of 2.6 kcal/g.
Hydroviton 24 is highly hygroscopic and has a pleasant, sweet taste.
Hydroviton 24 maintains moistness in shredded coconut, pet foods, and candy.
In sugarless frozen desserts, Hydroviton 24 depresses the freezing point, adds solids, and contributes some sweetness.
Hydroviton 24 is used in low-calorie beverages to provide body and taste.
Hydroviton 24 is used in dietary foods such as sugarless candy, chewing gum, and ice cream.
Hydroviton 24 is also used as a crystallization modifier in soft sugar-based confections.

Production method
1. Pour the prepared 53% aqueous solution of glucose into the autoclave, adding the nickel catalyst of 0.1% the weight of glucose; after replacement of the air, add hydrogen at about 3.5MPa, 150 °C, and pH8.2-8.4; control the endpoint with residual sugar content being lower than 0.5%.
After precipitation for 5 min, put the resulting solution of sorbitol through ion exchange resin to obtain the refined product.
Material fixed consumption amount: hydrochloric acid 19kg/t, caustic 36kg/ t, solid base 6kg/t, aluminum-nickel alloy powder 3kg/t, orally administrated glucose 518kg/t, activated carbon 4kg/t.

2. Hydroviton 24 is obtained from the hydrogenation of glucose with the nickel catalyst at high temperature and high pressure after which the product is further refined through the ion exchange resin, concentrated,crystallized, and, separated to obtain the final product.

3. Domestic production of sorbitol mostly applied continuously or intermittently hydrogenation of refined glucose obtained from starch saccharification:
C6H12O6 + H2 [Ni] → C6H14O6
Pour the prepared 53% aqueous solution of glucose into the autoclave, adding the nickel catalyst of 0.1% the weight of glucose; after replacement of the air, add hydrogen at about 3.5MPa, 150 °C, and pH8.2-8.4; control the endpoint with residual sugar content being lower than 0.5%. After precipitation for 5 min, put the resulting solution of sorbitol through ion exchange resin to obtain the refined product.
The above-mentioned process is simple without the necessity of isolation before obtaining qualified products as well as without "three wastes" pollution.
However, for the starch, the yield is only 50%, and thus has a higher cost.
Introduction of new technology by direct hydrogenation on starch saccharification liquid can obtain a yield up to 85%.
HYDROXYACETIC ACID
Hydroxyacetic Acid is a compound that naturally occurs in certain fruits, beets, and sugarcane.
In its pure form, Hydroxyacetic Acid is odorless and colorless.


CAS Number: 79-14-1
EC Number: 201-180-5
MDL Number: MFCD00004312
Molecular Formula: C2H4O3 / HOCH2COOH



Glycollate, -Hydroxy Fatty Acid, Glycollic Acid, Glycocide, Caswell No. 470, Dexon (Polyester), Polyglycollic Acid, Glycolate, Poly(L-Glycolic Acid), Glycolic Acid, Glycolic Acid Homopolymer, Glycolic acid, Glycollic acid, Hydroxyacetic acid, Hydroxyethanoic acid, Acetic acid, hydroxy-, glycolic acid, 2-Hydroxyacetic acid, hydroxyacetic acid, 79-14-1, Hydroxyethanoic acid, Glycollic acid, Acetic acid, hydroxy-, glycolate, Polyglycolide, Caswell No. 470, 2-Hydroxyethanoic acid, HOCH2COOH, alpha-Hydroxyacetic acid, Acetic acid, 2-hydroxy-, EPA Pesticide Chemical Code 000101, HSDB 5227, NSC 166, Glycocide, GlyPure, BRN 1209322, NSC-166, EINECS 201-180-5, UNII-0WT12SX38S, MFCD00004312, GlyPure 70, 0WT12SX38S, CCRIS 9474, DTXSID0025363, CHEBI:17497, Hydroxyacetic acid-13C2, .alpha.-Hydroxyacetic acid, GLYCOLLATE, DTXCID105363, NSC166, EC 201-180-5, 4-03-00-00571 (Beilstein Handbook Reference), GOA, GLYCOLIC ACID (MART.), GLYCOLIC ACID [MART.], C2H3O3-, glycolicacid, C2H4O3, Glycolate Standard: C2H3O3- @ 1000 microg/mL in H2O, Hydroxyethanoate, a-Hydroxyacetate, OceanBlu Barrier, OceanBlu Pre-Post, hydroxy-acetic acid, 2-Hydroxyaceticacid, alpha-Hydroxyacetate, a-Hydroxyacetic acid, 2-hydroxy acetic acid, 2-hydroxy-acetic acid, 2-hydroxyl ethanoic acid, HO-CH2-COOH, Hydroxyacetic acid solution, bmse000245, WLN: QV1Q, GLYCOLIC ACID [MI], Glycolic acid (7CI,8CI), GLYCOLIC ACID [INCI], GLYCOLIC ACID [VANDF], Glycolic acid, p.a., 98%, pari 30% Glycolic Acid Peel, pari 70% Glycolic Acid Peel, Acetic acid, hydroxy- (9CI), CHEMBL252557, GLYCOLIC ACID [WHO-DD], Glycolic Acid, Crystal, Reagent, HYDROXYACETIC ACID [HSDB], BCP28762, Glycolic acid, >=97.0% (T), STR00936, Tox21_301298, s6272, AKOS000118921, Glycolic acid, ReagentPlus(R), 99%, CS-W016683, DB03085, HY-W015967, SB83760, CAS-79-14-1, USEPA/OPP Pesticide Code: 000101, NCGC00160612-01, NCGC00160612-02, NCGC00257533-01, FT-0612572, FT-0669047, G0110, G0196, Glycolic acid 100 microg/mL in Acetonitrile, EN300-19242, Glycolic acid, SAJ special grade, >=98.0%, C00160, C03547, D78078, Glycolic acid, Vetec(TM) reagent grade, 98%, HYDROXYACETIC ACID, HYDROXYETHANOIC ACID, Glycolic acid, BioXtra, >=98.0% (titration), Q409373, J-509661, F2191-0224, Hydroxyacetic acid, Hydroxyethanoic acid, Glycollic acid, Z104473274, 287EB351-FF9F-4A67-B4B9-D626406C9B13, Glycolic acid, certified reference material, TraceCERT(R), Glycolic acid, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%, Glycolic Acid, Pharmaceutical Secondary Standard, Certified Reference Material O7Z, Hydroxyacetic acid, Glycolic acid, Glycolic Acid, Hydroxyacetic Acid, Aceticacid,hydroxy-, acidehydroxyacetique, hydroxyaceticacid, glycolic, AHA, 2-HYDROXYACETIC ACID, GLYCOLATE, glycolic, HYDROXYACETIC ACID, HOCH2COOH, GLYCOLLIC ACID, Glycolic acid 70%, GLYCOLIC ACID SIGMAULTRA, glycolate (hydroxyacetate), GLYCOLIC ACID, HIGH PURITY, 70 WT.% SOLU TION IN WATER, 2-Hydroxyacetate, 2-Hydroxyacetic acid, A-Hydroxyacetate, A-Hydroxyacetic acid, Alpha-Hydroxyacetate, Alpha-Hydroxyacetic acid, Glycocide, Glycolate, Glycolic acid, Glycollate, Glycollic acid, GlyPure, GlyPure 70, Hydroxyacetate, Hydroxyacetic acid, Hydroxyethanoate, Hydroxyethanoic acid, Sodium glycolate, Sodium glycolic acid, α-Hydroxyacetate, α-Hydroxyacetic acid, 2-Hydroxy carboxylate, 2-Hydroxy carboxylic acid, 2-Hydroxyacetate, 2-Hydroxyacetic acid, 2-Hydroxyethanoate, 2-Hydroxyethanoic acid, a-Hydroxyacetate, a-Hydroxyacetic acid, Acetic acid, 2-hydroxy-, Acetic acid, hydroxy- (9CI),



Hydroxyacetic Acid that cosmetic companies use tends to come from a laboratory rather than natural sources.
Hydroxyacetic Acid is a constituent of sugar cane juice
Hydroxyacetic Acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.


Hydroxyacetic Acid has a role as a metabolite and a keratolytic drug.
Hydroxyacetic Acid belongs to a group of acids experts refer to as alpha hydroxy acids (AHAs).
Hydroxyacetic Acid is an alpha hydroxy acid; used in chemical peels and anti-aging skin products.


Hydroxyacetic Acid is a type of alpha hydroxy acid (AHA).
Alpha hydroxy acids are natural acids found in foods.
Hydroxyacetic Acid comes from sugarcane.


Don't confuse Hydroxyacetic Acid with other alpha hydroxy acids, including citric acid, lactic acid, malic acid, and tartaric acid.
These are not the same.
Hydroxyacetic Acid is an organic substance with the chemical formula C2H4O3.


Hydroxyacetic Acids are popular ingredients in skin care products.
Hydroxyacetic Acid is a naturally occurring alpha hydroxy acids (or AHAs).
Hydroxyacetic Acid is colorless and easily deliquescent crystal.


Hydroxyacetic Acid is soluble in water, methanol, ethanol, ethyl acetate and other organic solvents, slightly soluble in ether, insoluble in hydrocarbons.
Once applied, Hydroxyacetic Acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.


This allows the outer skin to dissolve revealing the underlying skin.
Hydroxyacetic Acid is the only domestically produced hydroxyacetic acid.
Hydroxyacetic Acid is supplied in a 70% chloride-free solution resulting in low corrosivity, making it ideal for a versatile range of cleaning and industrial applications.


Hydroxyacetic Acid is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water.
Hydroxyacetic Acid, also known as hydroxy acetic acid, is one of the alpha-hydroxy acids (AHA’s).
These acids occur naturally in fruits, sugar cane and milk.


When used topically, Hydroxyacetic Acid can assist with the removal of dead skin cells helping to renew the skin.
Hydroxyacetic Acid is an organic acid from the family of alpha-hydroxy carboxylic acids that naturally occurs in sugarcane, beets, grapes, and fruits.
Hydroxyacetic Acid has the duality of alcohol and acid and decomposes when heated to boiling point.


Hydroxyacetic Acid is one of the simplest organic compounds, used on a broad scale in contemporary cosmetology and in the chemical industry.
This is because that hydracid has many valuable properties.
Hydroxyacetic Acid in cosmetics: a regenerating glycol for the face and body.


Industrialists and pharmacists discovered long ago that Hydroxyacetic Acids are worth using on the face and skin.
They are ingredients of creams, conditioners, shampoos, ointments and tonics as well as additives in washing gels, exfoliation products, etc.
Hydroxyacetic Acid is the first member of the series of alpha-hydroxy carboxylic acids, which means it is one of the smallest organic molecules with both acid and alcohol functionality.


Hydroxyacetic Acid is a 2-hydroxy monocarboxylic acid and a primary alcohol.
Hydroxyacetic Acid is functionally related to an acetic acid.
Hydroxyacetic Acid is a conjugate acid of a glycolate.


Hydroxyacetic Acid is a metabolite found in or produced by Escherichia coli.
Hydroxyacetic Acid is the smallest alpha-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid, Hydroxyacetic Acid, is highly soluble in water.


Hydroxyacetic Acid is the first member of the series of alpha-hydroxy carboxylic acids, which means it is one of the smallest organic molecules with both acid and alcohol functionality
Hydroxyacetic Acid is the smallest α-hydroxy acid (AHA).


This colorless, odorless, and hygroscopic crystalline solid, Hydroxyacetic Acid, is highly soluble in water.
A water solution form is also available.
Hydroxyacetic Acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.


The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.


Due to its excellent capability to penetrate the skin, Hydroxyacetic Acid finds applications in skin care products, most often as a chemical peel.
Hydroxyacetic Acid may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis.


Hydroxyacetic Acid is soluble in water, alcohol, and ether.
AHA acids (alpha hydroxyacids) cover various types of popular acids that we use on a daily basis.
Examples include citric, lactic or malic acid.


The AHAs also cover Hydroxyacetic Acid.
Hydroxyacetic Acid is the smallest α-hydroxy acid (AHA).
Hydroxyacetic Acid appears in the form of a colorless, odorless and hygroscopic crystalline solid that is highly soluble in water and related solvents.


Hydroxyacetic Acid is associated with sugar-crops and is isolated from sugarcane, sugar beets, pineapple, canteloupe, and unripe grapes.
Hydroxyacetic Acid is the first member of the series of alpha-hydroxy carboxylic acids, which means it is one of the smallest organic molecules with both acid and alcohol functionality.


Hydroxyacetic Acid is soluble in water, alcohol, and ether.
Hydroxyacetic Acid is the smallest alpha-hydroxy acid (AHA).
Hydroxyacetic Acid is mainly supplemented to various skin-care products to improve the skin’s appearance and texture.


Hydroxyacetic Acid can also reduce wrinkles, acne scarring, and hyperpigmentation.
Hydroxyacetic Acid is a colorless, odourless, and hygroscopic crystalline solid with the chemical formula C2H4O3.
Hydroxyacetic Acid is also known as hydroacetic acid, or 2-hydroxyethanoic acid, and its IUPAC name is hydroxyacetic acid.


Hydroxyacetic Acid is a solid that excellently absorbs water molecules from the environment.
There are several names denoting Hydroxyacetic Acid: its chemical name is 2-Hydroxyethanoic acid.
That name was introduced by the International Union of Pure and Applied Chemistry (IUPAC) to facilitate the identification of that substance on a global market.


Hydroxyacetic Acid compound can also be found under the following names: hydroxyacetic acid, alpha-hydroxyacetic acid, hydroxyethanoic acid.
Hydroxyacetic Acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic Acid has a role as a metabolite and a keratolytic drug.


Hydroxyacetic Acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic Acid is an alpha hydroxy acid that has antibacterial, antioxidant, keratolytic, and anti-inflammatory properties.
Hydroxyacetic Acid is functionally related to acetic acid and is slightly stronger than it.


The salts or esters of glycolic acid are called glycolates.
Hydroxyacetic Acid is widespread in nature and can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroxyacetic Acid is a routine essential.


Hydroxyacetic Acid can be found amongst our exfoliating, fine line fighting beauty products – it’s nothing new but that doesn’t mean it doesn’t deserve a shoutout for being a damn powerhouse.
Various oligomers or polymers of lactic and/or Hydroxyacetic Acid (low molecular weight) have been prepared.


Hydroxyacetic Acid can be determined via plant tissue coupled flow injection chemiluminescence biosensors, which can be used both as a plant-tissue based biosensor and chemiluminescence flow sensor.
Hydroxyacetic Acid is a naturally occurring alpha hydroxy acids (or AHAs).


Hydroxyacetic Acid is a type of alpha hydroxy acid (AHA) made from sugar cane that can act like a water-binding agent.
Glycolic is the most researched and purchased type of alpha hydroxy acid on the market that has all its effects backed up by studies.
Hydroxyacetic Acid; chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest α-hydroxy acid (AHA).


Hydroxyacetic Acid is the smallest alpha-hydroxy acid.
Hydroxyacetic Acid solution is a useful solution of acid.
Hydroxyacetic Acid is an AHA, aka alpha hydroxy acid.


Some other acids that fall under the Hydroxyacetic Acid umbrella include lactic and citric acids.
Hydroxyacetic Acid’s are usually derived from natural sources; lactic from milk, citric from citrus and glycolic from sugarcane, pineapple, canteloupe or unripe grapes.


Hydroxyacetic Acid is a useful intermediate for synthesis.
The most useful synthesis use is for oxidation reduction esterification and long chain polymerization.
Hydroxyacetic Acid, also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.


These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroxyacetic Acid is an extremely weak basic (essentially neutral) compound (based on its pKa).
Hydroxyacetic Acid exists in all living species, ranging from bacteria to humans.


In humans, Hydroxyacetic Acid is involved in rosiglitazone metabolism pathway.
Outside of the human body, Hydroxyacetic Acid has been detected, but not quantified in, several different foods, such as sourdocks, pineappple sages, celeriacs, cloves, and feijoa.


Hydroxyacetic Acid’s are not only beneficial when applied topically but due to their molecular size (teeny tiny), they’re pretty good at getting under the skin and putting in the extra effort from the inside too.
You will commonly find Hydroxyacetic Acid in your cleansers, toners, exfoliants, and collagen stimulating products.


Hydroxyacetic Acid is an α-hydroxy acid.
Hydroxyacetic Acid solutions having concentration of 70% and pH range of 0.08 to 2.75 are widely employed as superficial chemical peeling agents.
This could make Hydroxyacetic Acid a potential biomarker for the consumption of these foods.


Hydroxyacetic Acid, with regard to humans, has been found to be associated with several diseases such as transurethral resection of the prostate and biliary atresia; glycolic acid has also been linked to several inborn metabolic disorders including glutaric acidemia type 2, glycolic aciduria, and d-2-hydroxyglutaric aciduria.


Hydroxyacetic Acid and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis.
Hydroxyacetic Acid, also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.
These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.


Hydroxyacetic Acid is an extremely weak basic (essentially neutral) compound (based on its pKa).
Hydroxyacetic Acid exists in all living species, ranging from bacteria to humans.
Hydroxyacetic Acid; chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest α-hydroxy acid (AHA).


This colorless, odorless, and hygroscopic crystalline solid, Hydroxyacetic Acid, is highly soluble in water.
Hydroxyacetic Acid 99% crystals reagent is a highly pure form of glycolic acid that is commonly used in various industries, including cosmetics, pharmaceuticals, and chemical manufacturing.


Hydroxyacetic Acid is known for its ability to exfoliate and improve skin texture, making it a popular ingredient in skincare products.
Once applied, Hydroxyacetic Acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.



USES and APPLICATIONS of HYDROXYACETIC ACID:
Cosmetic and pharmaceutical companies include Hydroxyacetic Acid in topical products to treat skin conditions or to improve skin texture and appearance.
Hydroxyacetic Acid is used to evaluate the efficacy of glycolic peels treatment for all types of acne.
Hydroxyacetic Acid is used in the fine synthesis of medicine and as a raw material of cosmetics and organic synthesis.


Hydroxyacetic Acid can be used as an exfoliant if concentrated properly at 5%.
Hydroxyacetic Acid can help shed dead skin and renew surface skin, improving visible signs of ageing, such as uneven skin tone, sun damage, fine lines, rough or patchy skin, and vastly reduce the size of wrinkles.


To obtain all these benefits you will need a leave-on AHA exfoliator which is 5%-10% Hydroxyacetic Acid that is formulated at a pH level of 3-4 and then the product must be rinsed off thoroughly.
Hydroxyacetic Acid is not only a popular ingredient in skincare products, it is also used in the textile industry and in food processing as a flavoring agent and a preservative.


Hydroxyacetic Acid is used Facial care (exfoliating products, peelings, purifying creams and lotions, cleansing gels, radiance masks, eye contour creams, anti-imperfections care, beard creams, unifying care).
Hydroxyacetic Acid is used Body care (body milks, shower gels).


Hydroxyacetic Acid is used Hair care (anti-dandruff shampoos, purifying hair masks).
Alpha hydroxy acids like Hydroxyacetic Acid work by removing the top layers of dead skin cells.
Hydroxyacetic Acid is used Peels, creams, lotions, masks, cleansers.


Due to Hydroxyacetic Acid's acidity the final product needs to be tested for safe pH.
Hydroxyacetic Acid also seems to help reverse sun damage to the skin.
People use Hydroxyacetic Acid for acne, aging skin, dark skin patches on the face, and acne scars.


Hydroxyacetic Acid is also used for stretch marks and other conditions, but there is no good scientific evidence to support these other uses.
Uses of Hydroxyacetic Acid: Acid Cleaners, Concrete Cleaners, Food Processing, Hard Surface Cleaners, Leather-Dyeing and Tanning, Petroleum Refining, Textile, and Water Treatment.


Textiles uses of Hydroxyacetic Acid: In addition to Hydroxyacetic Acid acne products, the chemical is an excellent product for the textile industry, where it is used for dyeing and tanning purposes.
The optimal pH range of Hydroxyacetic Acid is from 3.5-5.0.


Some over the counter products, after adding Hydroxyacetic Acid, will separate as a result of the low pH, and need to be stabilized.
Hydroxyacetic Acid is commonly used in chemical milling, cleaning, and polishing of metals, and in copper pickling solutions.
Food: One of the key Hydroxyacetic Acid benefits is that it works as a flavor enhancer and food preservative.


Hydroxyacetic Acid is used in the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.
Hydroxyacetic Acid is often useful for dyeing and tanning, and is often included in emulsion polymers, solvents and additives for ink and paint.


Hydroxyacetic Acid is metabolized by cells in vitro to become oxalic acid which kills cells.
Hydroxyacetic Acid is synthesized many ways but is often isolated from sugarcane, pineapples and other acidic tasting fruits.
Hydroxyacetic Acid is the smallest alpha-hydroxy acid (AHA).


In its pure form, Hydroxyacetic Acid is a colorless crystalline solid.
Due to its excellent capability to penetrate skin, Hydroxyacetic Acid finds applications in skin care products, most often as a chemical peel.
Hydroxyacetic Acid is also used for tattoo removal.


In E coli Hydroxyacetic Acid is involved in glyoxylate and dicarboxylate metabolism.
Additionally, Hydroxyacetic Acid is used in the production of various chemicals, such as polymers and esters, and as a pH adjuster in various formulations.
Its high purity and effectiveness make Hydroxyacetic Acid a valuable tool in many applications.


Hydroxyacetic Acid was once most commonly used as a chemical peel by dermatologists, this was because out of all AHAs, glycolic has the lowest molecular weight, meaning it has the ability to penetrate the skin even deeper than most other AHAs, making it more effective when it comes to reducing wrinkles, acne scarring, hyperpigmentation and improving other skin conditions.


Due to its excellent capability to penetrate skin, Hydroxyacetic Acid is often used in skin care products, most often as a chemical peel.
Hydroxyacetic Acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
Hydroxyacetic Acid is the most commonly used natural AHA (= alpha hydroxy acid).


Hydroxyacetic Acid is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroxyacetic Acid is extracted from sugar cane, grapes and wine leaves.


Typical use level of Hydroxyacetic Acid is between 1-20% (final concentration of glycolic acid).
For making a 10% AHA peel, use about 14.5% of Hydroxyacetic Acid, making a 5% AHA peel, use about 7.2%.
For home use, Hydroxyacetic Acid is not recommended to make AHA peels higher than 20% (equals about 28.5% of glycolic acid).


Hydroxyacetic Acid is used Peels, creams, lotions, masks, cleansers.
Due to Hydroxyacetic Acid's acidity the final product needs to be tested for safe pH.
Optimal pH range of Hydroxyacetic Acid is from 3.5-5.0.


Some over the counter products, after adding Hydroxyacetic Acid, will separate as a result of the low pH, and need to be stabilized.
Hydroxyacetic Acid has been used in the preparation of PLGA-PEG-PLGA copolymer (PLGA = poly(lactic/glycolic, PEG = polyethylene glycol).
Hydroxyacetic Acid is used as a monomer to create PLGA and other biocompatible copolymers.


Hydroxyacetic Acid reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles.
Hydroxyacetic Acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells.


Hydroxyacetic Acid is also used in the cosmetic industry in skin peels.
Hydroxyacetic Acid is also used for diminishing the signs of age spots, as well as actinic keratosis.
However, Hydroxyacetic Acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles.


Regardless of the G skin type, Hydroxyacetic Acid use is associated with softer, smoother, healthier, and younger looking skin.
Hydroxyacetic Acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.
Hydroxyacetic Acid is also an excellent alternative to toxic and low penetration acids such as sulfuric, phosphoric, and sulfamic in cleaners, water treatment chemicals, and O&G applications.


Hydroxyacetic Acid is preffered nowadays due to its high speed of action, scale removal performance, less corrosivity, biodegredability, and less hazardous waste stream.
Personal and Skincare Products uses of Hydroxyacetic Acid: Anti-aging creams, acne treatments, exfoliating scrubs, hair conditioners, and other hair care products.


Hydroxyacetic Acid also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water.
This occurs in the cellular cement through an activation of Hydroxyacetic Acid and the skin’s own hyaluronic acid content.
Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by Hydroxyacetic Acid.


Household, Institutional, and Industrial Cleaning Products uses of Hydroxyacetic Acid: Hard surface cleaners, metal cleaners, toilet bowl cleaners, and laundry sours.
Water Treatment Applications of Hydroxyacetic Acid: Boiler cleaning chemicals, well stimulating solutions, and process cleaning products.


Hydroxyacetic Acid is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).
Among other uses Hydroxyacetic Acid finds employment in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative.


Hydroxyacetic Acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.
Hydroxyacetic Acid is used in the textile industry as a dyeing and tanning agent.
Hydroxyacetic Acid is widely used in skin care products as an exfoliant and keratolytic.


Hydroxyacetic Acid is used in the textile industry as a dyeing and tanning agent.
Hydroxyacetic Acid is used in the processing of textiles, leather, and metals.
Electronics and Metal Surface Treatment uses of Hydroxyacetic Acid: Etching chemicals, printed circuit board fluxes, electropolishing chemicals, and metal surface preparations.


Oil and Gas Applications of Hydroxyacetic Acid: Oil drilling chemicals, well stimulation, mid-and downstream descalers, and general process scale removers.
Hydroxyacetic Acid is used for organic synthesis, etc
Industries: Adhesives | Building & Construction | Care Chemicals | Energy | Inks | Maintenance, Repair, Overhaul | Metal Processing & Fabrication | Transportation | Water Treatment


As a result, the skin’s own ability to raise Hydroxyacetic Acid's moisture content is increased.
Hydroxyacetic Acid is the simplest alpha hydroxyacid (AHA).
Hydroxyacetic Acid is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight.


Due to its excellent capability to penetrate skin, Hydroxyacetic Acid finds applications in skin care products, most often as a chemical peel performed by a dermatologist in concentrations of 20%-80% or at-home kits in lower concentrations of 10%.
Hydroxyacetic Acid is used to improve the skin's appearance and texture.


Hydroxyacetic Acid may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions.
Once applied, Hydroxyacetic Acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.


This allows the outer skin to "dissolve" revealing the underlying skin.
Hydroxyacetic Acid is also a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.


Hydroxyacetic Acid is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH.
Hydroxyacetic Acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes.
Formulations based on that acid are also used in beauty salons as part of rejuvenating treatments.


Hydroxyacetic Acid is used in the textile industry as a dyeing and tanning agent.
Cleaning and washing concentrates with Hydroxyacetic Acid quickly remove dirt and microbes from different surfaces.
Hydroxyacetic Acid is also used in adhesives and plastics.
Hydroxyacetic Acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.


Hydroxyacetic Acid is used in surface treatment products that increase the coefficient of friction on tile flooring.
Hydroxyacetic Acid is the active ingredient in the household cleaning liquid Pine-Sol.
In textile industry, Hydroxyacetic Acid can be used as a dyeing and tanning agent.


Hydroxyacetic Acid can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.
Hydroxyacetic Acid can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss.
Moreover, Hydroxyacetic Acid is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.


Hydroxyacetic Acid can be used in organic synthesis and printing and dyeing industry.
Hydroxyacetic Acid can be used for sterilization of soap.
Hydroxyacetic Acid can be used as a complexing agent for electroless nickel plating to improve the coating quality, and can also be used as an additive for other electroplating or electroless plating


Available in various quantities, Hydroxyacetic Acid is used as a dyeing and tanning agent, a flavoring agent and preservative, an intermediate for organic synthesis, etc.
Hydroxyacetic Acid is most commonly used for hyperpigmentation, fine lines and acne.


Hydroxyacetic Acid is mostly found in exfoliating products (peels), or in creams and lotions but at a much lower concentration. Hydroxyacetic Acid is obtained by synthesis.
Hydroxyacetic Acid is an acid and should never be used undiluted.


This is why they are widely used in private homes, industrial plants and public facilities.
Hydroxyacetic Acid is also desired by entities from the food, logistic and catering industries.
Hydroxyacetic Acid can also be found at schools and kindergartens.


Hydroxyacetic Acid is classed as an advanced skincare ingredient and should not be used unless you understand the usage and applications of Glycolic Acid.
Glycolic is a commonly known ingredient in the personal care and cosmetics market and Hydroxyacetic Acid is also widely used in several household and industrial cleaning applications.


Hydroxyacetic Acid is commonly used in chemical milling, cleaning, and polishing of metals, and in copper pickling solutions. Hydroxyacetic Acid is also used in the cosmetic industry in skin peels.
Hydroxyacetic Acid is a naturally occurring alpha hydroxy Hydroxyacetic Acid is very useful in exfoliating products as alpha-hydroxy acid peel, or in creams & lotions at a lower concentration for a more gentle acid-based peel.


Hydroxyacetic Acid is widely used to rejuvenate the skin by encouraging the shedding of old surface skin cells.
Hydroxyacetic Acid is used in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent.


Hydroxyacetic Acid is used in various skin-care products.
Hydroxyacetic Acid is widespread in nature.
A glycolate (sometimes spelled "glycollate") is a salt or ester of Hydroxyacetic Acid.


-Applications of Hydroxyacetic Acid:
Today’s drug or household chemical stores offer various types of agents and formulations containing Hydroxyacetic Acid.
Their application is very wide.

Hydroxyacetic acid is a component of:
*concentrates designed for the cleaning of Gres tiles, joints and porous surfaces,
*specialised preparations for washing and sterilizing tanks, cisterns, *production lines or equipment having contact with food,
*liquids used for cleaning public sanitary facilities.


-Skin care uses of Hydroxyacetic Acid:
Dermatologists commonly use Hydroxyacetic Acid for acne treatment and other skin condition.
Hydroxyacetic Acid skin care products are made to safely penetrate skin to exfoliate skin, reduce scarring from acne and reduce wrinkling.



BENEFITS OF HYDROXYACETIC ACID FOR THE SKIN:
Research suggests that Hydroxyacetic Acid may help with the following:

*Acne:
Older research from 1999 examined the effect of a peel containing 70% Hydroxyacetic Acid on 80 females with acne.
The research found that it quickly improved all types of acne, particularly comedonal acne, which occurs when pores become clogged with oil and dead skin cells.

Hydroxyacetic Acid is of note, however, that this strength of Hydroxyacetic Acid is only available as a chemical peel.
Over-the-counter (OTC) Hydroxyacetic Acid products are not this strong.

*UV damage
Exposure to UV light can cause skin damage.
The visible signs of this include:
-sunspots,
-hyperpigmentation,
-wrinkles,

Health experts refer to this as photoaging.
A 2020 study notes that Hydroxyacetic Acid is an effective treatment for sun damage in the skin.
A 2018 paper also reports that Hydroxyacetic Acid has a protective effect against UVB rays, meaning it may help prevent photoaging.


*Lines and wrinkles:
Over time, the skin loses its plumpness and elasticity.
As a result, fine lines and wrinkles can form.
This is a natural process and not necessarily something a person needs to treat.
However, for those who choose to, Hydroxyacetic Acid may help.

According to a 2020 study, Hydroxyacetic Acid:
-increases skin levels of hyaluronic acid, a substance that helps keep the skin moisturized
-stimulates the production of collagen, the main structural protein in the skin
-increases fibroblast and keratinocyte proliferation rates, which help with skin repair and regeneration
-improves quality of elastin, which promotes skin elasticity


*Warts:
Warts are small, hard growths on the skin that occur due to viruses.
An older 2011 study tested the effectiveness of a 15% Hydroxyacetic Acid treatment in 31 HIV-positive children with warts.
The results indicate that the treatment helped flatten and normalize the color of the warts, but Hydroxyacetic Acid only completely cleared them in 10% of the participants.
Other research from 2011 evaluated the effectiveness of a gel containing 15% Hydroxyacetic Acid and 2% salicylic acid in 20 people with warts.
The research found that the gel worked very well.



FUNCTIONS OF HYDROXYACETIC ACID:
*The 70% solution can be used as cleaning agent.
*The 99.5% Crystal can be used in the fine synthesis of medicine.
*Hydroxyacetic Acid is used as ingredient of cosmetics, adhesives, petroleum emulsion splitter, soldering paster and coatings.



CHEMICAL PROPERTIES OF HYDROXYACETIC ACID:
Hydroxyacetic Acid, CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF).
Hydroxyacetic Acid is soluble in water,alcohol,and ether.
Hydroxyacetic Acid is used in dyeing, tanning, electropolishing,and in foodstuffs.
Hydroxyacetic Acid is produced by oxidizing glycol with dilute nitric acid.



PRODUCTION METHOD OF HYDROXYACETIC ACID:
The contemporary cosmetic and chemical markets would be hard to imagine without substances such as AHAs, including Hydroxyacetic Acid. What is this semi-finished product made of?
For decades, various methods of producing Hydroxyacetic Acid were developed.

Hydroxyacetic Acid can be obtained, for example, by:
A reaction of acetic (chloroacetic) acid derivative with sodium hydroxide (NaOH), which is a strong base.
Obviously, Hydroxyacetic Acid will not be produced immediately.

The production of Hydroxyacetic Acid is only possible if the environment of both reacting ingredients is acidified.
A reaction of formaldehyde with water gas (it is one of the most popular methods of the mass production of Hydroxyacetic Acid; however, the acquisition of the semi-finished product with this method generates a lot of waste).



OTHER TYPES OF HYDROXYACETIC ACID INCLUDE:
*citric acid, which is present in citrus fruits
*malic acid, which is present in apples
*lactic acid, which is present in milk
Of these, Hydroxyacetic Acid has the smallest molecular structure, which likely allows it to penetrate deeper into the skin.



CHEMICAL AND STRUCTURAL FORMULAS OF HYDROXYACETIC ACID:
Hydroxyacetic Acid'structural formula is the following: HOCH2COOH.
The molecular formula of Hydroxyacetic Acid is: C2H4O3.
Both formulas indicate that Hydroxyacetic Acid contains both carboxyl and the hydroxyl groups, which are typical of alpha-hydroxyacids.



OCCURRENCE OF HYDROXYACETIC ACID:
Plants produce Hydroxyacetic Acid during photorespiration.
Hydroxyacetic Acid is recycled by conversion to glycine within the peroxisomes and to tartronic acid semialdehyde within the chloroplasts.



HOW TO RECOGNISE HYDROXYACETIC ACID?
The characteristics of that Hydroxyacetic Acid are as follows: it is a solid having the form of a white or transparent, crystalline, odourless powder.
Hydroxyacetic Acid decomposes at 100°C and melts at 80°C.
It is assumed that Hydroxyacetic Acid has a density of 1.49 g/cm³ at around 25°C.



PROPERTIES OF HYDROXYACETIC ACID:
Hydroxyacetic Acid has the following properties:
*Exfoliative:
As a chemical exfoliant, Hydroxyacetic Acid removes the outermost layer of skin cells and oil by dissolving them.
Unlike mechanical exfoliants, such as face scrubs and brushes, Hydroxyacetic Acid does not require harsh scrubbing.


*Humectant:
Hydroxyacetic Acid is also a humectant, which means it attracts and binds water to skin cells.
Hydroxyacetic Acid does this by increasing the synthesis of glycosaminoglycans, which are molecules that draw water in the skin.


*Antibacterial:
A 2020 study states that, at certain concentrations, Hydroxyacetic Acid can inhibit the growth of bacteria.


*Anti-aging:
Hydroxyacetic Acid can reduce some of the processes that cause visible signs of skin aging.
For example, Hydroxyacetic Acid can reduce sun damage and increase collagen and hyaluronic acid in the skin.
These substances give skin elasticity and structure.



PREPARATION OF HYDROXYACETIC ACID:
Hydroxyacetic Acid can be synthesized in various ways.
The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.

Hydroxyacetic Acid is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.

Some of today's Hydroxyacetic Acids are formic acid-free.
Hydroxyacetic Acid can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.
Hydroxyacetic Acid can also be prepared using an enzymatic biochemical process that may require less energy.



PROPERTIES OF HYDROXYACETIC ACID:
Hydroxyacetic Acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions, forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of Hydroxyacetic Acid's proton.



ALTERNATIVE PARENTS OF HYDROXYACETIC ACID:
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Primary alcohols
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF HYDROXYACETIC ACID:
*Alpha-hydroxy acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Primary alcohol
*Organooxygen compound
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound



PREPARATION OF HYDROXYACETIC ACID:
Hydroxyacetic Acid is isolated from natural sources and is inexpensively available.
Hydroxyacetic Acid can be prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Hydroxyacetic Acid can also be prepared using an enzymatic biochemical process which produces fewer impurities compared to traditional chemical synthesis, requires less energy in production and produces less co-product.



CHEMICAL PROPERTIES OF HYDROXYACETIC ACID:
Hydroxyacetic Acid is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroxyacetic Acid is used as a monomer in the preparation of Poly(lactic-co-glycolic acid) (PLGA).
Hydroxyacetic Acid reacts with lactic acid to form PLGA using ring-opening co-polymerization.
Polyglycolic acid (PGA) is prepared from the monomer Hydroxyacetic Acid using polycondensation or ring-opening polymerization.



THE BENEFITS OF HYDROXYACETIC ACID:
Exfoliates dead skin cells to reveal softer, smoother skin
- Hydroxyacetic Acid works by loosening the binding between dead skin cells, allowing them to slough off.

Reduces acne:
- by encouraging the shedding or peeling of cells on the skin's surface and lining the pores, Hydroxyacetic Acid prevents the formation of clogged pores—it also has antibacterial and anti-inflammatory properties.

Stimulates collagen production from within:
- Hydroxyacetic Acid's work on the skin's deeper layers to boost collagen production.
You will notice smooth skin almost immediately however Hydroxyacetic Acid can take a wee bit of time to notice an improvement in those fine lines and wrinkles.



PREPARATION OF HYDROXYACETIC ACID:
There are different preparation methods to synthesize Hydroxyacetic Acid.
However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less.
Hydroxyacetic Acid can be produced when chloroacetic acid reacts with sodium hydroxide and then undergoes re-acidification.

Hydroxyacetic Acid can also be synthesized by electrolytic reduction of oxalic acid.
Hydroxyacetic Acid can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroxyacetic Acid can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.



CHEMICAL, HYDROXYACETIC ACID:
Hydroxyacetic Acid, due to its OH group, reacts with hydrogen halides, such as hydrogen chloride, to give their respective monohaloacetic acid, in this case chloroacetic acid.
Hydroxyacetic Acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.

The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.



PHYSICAL, HYDROXYACETIC ACID:
Hydroxyacetic Acid is a colorless solid, very soluble in water.
Hydroxyacetic Acid is odorless.



BENEFITS OF HYDROXYACETIC ACID:
*Hydroxyacetic Acid can reduce the appearance of fine lines, irregular pigmentation, age spots & decreases enlarged pores
*Hydroxyacetic Acid is very useful in exfoliating products as alpha-hydroxy acid peel, or in creams & lotions at a lower concentration for a more gentle acid-based peel
*Hydroxyacetic Acid is widely used to rejuvenate the skin by encouraging the shedding of old surface skin cells



PREPARATION OF HYDROXYACETIC ACID:
Hydroxyacetic Acid is often prepared by the reaction of chloroacetic acid with sodium hydroxide, followed by re-acidification.
Cl-CH2COOH + 2 NaOH → OH-CH2COONa + NaCl + H2O
OH-CH2COONa + HCl → OH-CH2COOH + NaCl

Another route involves the reaction of potassium cyanide with formaldehyde.
The resulting potassium glycolate is treated with acid and purified.
Hydroxyacetic Acid was historically first prepared by treating hippuric acid with nitric acid and nitrogen dioxide.

This forms and ester of benzoic acid and Hydroxyacetic Acid, which is hydrolyzed to glycolic acid by boiling it in sulfuric acid.
Hydrogenation of oxalic acid is another route.
Hydroxyacetic Acid can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.



INCORPORATING HYDROXYACETIC ACID INTO YOUR DAILY REGIME
All skin types can tolerate the use of Hydroxyacetic Acid; it’s best suited to acne-prone or oily skin



SCIENTIFIC FACTS OF HYDROXYACETIC ACID:
Hydroxyacetic Acid and Lactic Acid are alpha hydroxy acids (AHAs).
They may be either naturally occurring or synthetic.
They are often found in products intended to improve the overall look and feel of the skin.
Hydroxyacetic Acid is the most widely used of out of the group and is usually manufactured from sugar cane.
Lactic acid, derived primarily from milk and its origins can be traced back to Cleopatra, who purportedly used sour milk on her skin.



WHAT IS HYDROXYACETIC ACID?
Glycolic Acid and Lactic Acid are naturally occuring organic acids also known as Alpha Hydroxy Acids or AHAs.
The salts of Hydroxyacetic Acid (Ammonium Glycolate, Sodium Glycolate), the salts of Lactic Acid (Ammonium Lactate, Calcium Lactate, Potassiu
Lactate, Sodium Lactate, TEA-Lactate) and the esters of Lactic Acid (Methyl Lactate, Ethyl Lactate, Butyl Lactate, Lauryl Lactate, Myristyl Lactate, Cetyl Lactate) may also be used in cosmetics and personal care products.
In cosmetics and personal care products, these ingredients are used in the formulation of moisturizers, cleansing products, and other skin care products, as well as in makeup, shampoos, hair dyes and colors and other hair care products.



PREPARATION OF HYDROXYACETIC ACID:
There are different preparation methods to synthesize Hydroxyacetic Acid.
However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less.

Hydroxyacetic Acid can be prepared when chloroacetic acid reacts with sodium hydroxide and undergoes re-acidification. Electrolytic reduction of oxalic acid also could synthesize this compound.
Hydroxyacetic Acid can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroxyacetic Acid can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.



BENEFITS OF HYDROXYACETIC ACID:
Hydroxyacetic Acid addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.



ORGANIC SYNTHESIS OF HYDROXYACETIC ACID:
Hydroxyacetic Acid is a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.
Hydroxyacetic Acid is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).

Commercially, important derivatives include the methyl (CAS# 96-35-5) and ethyl (CAS# 623-50-7) esters which are readily distillable (boiling points 147–149 °C and 158–159 °C, respectively), unlike the parent acid.
The butyl ester (b.p. 178–186 °C) is a component of some varnishes, being desirable because it is nonvolatile and has good dissolving properties.



BENEFITS OF HYDROXYACETIC ACID FOR THE SKIN:
Hydroxyacetic Acid is a substance that chemically exfoliates a person’s skin by dissolving dead skin cells and oils.
Hydroxyacetic Acid may also help boost collagen production, and support skin moisture.

Hydroxyacetic Acid can remove the very top layer of skin cells without the need for scrubbing, which can cause irritation.
Hydroxyacetic Acid is also useful in treatments for acne, hyperpigmentation, and the visible signs of aging.

However, as with all chemical exfoliants, using Hydroxyacetic Acid too frequently, at too high a concentration, or incorrectly can result in skin irritation or damage.



WHAT ELSE DISTINGUISHES HYDROXYACETIC ACID?
The water solubility of Hydroxyacetic Acid is very good and largely depends on the temperature of the liquid: the higher it is, the better the powder will dissolve to form a solution.
Hydroxyacetic Acid can also be dissolved in alcohols: ethanol, methanol or acetone.
Hydroxyacetic Acid reacts with aluminium and oxidants, which may even cause ignition.



OPINIONS OF HYDROXYACETIC ACID:
Contemporary consumers search for proven, high-quality chemicals that bring rapid effects and do not cause allergies.
People are increasingly eager to choose natural Hydroxyacetic Acid and use cosmetics and chemicals which contain that ingredient.
Hydroxyacetic Acid, designed for professional use, is globally recognised as a substitute of many other acids produced artificially.
Industrial plants use C2H4O3, for example, instead of Hydroxyacetic Acid which, once used, turns into highly poisonous and hazardous waste.



WHY IS HYDROXYACETIC ACID INCREASINGLY POPULAR?
Hydroxyacetic Acid's effects can be noticed within a few days.
With that Hydroxyacetic Acid, the epidermis regenerates faster and recovers its natural colour and flexibility.
Hydroxyacetic Acid can also be used against discolouration, inflammatory conditions and scars.
Amongst cosmetic ingredients, we can find it under the INCI name Hydroxyacetic Acid.



HISTORY OF HYDROXYACETIC ACID:
The name "Hydroxyacetic Acid" was coined in 1848 by French chemist Auguste Laurent (1807–1853).
He proposed that the amino acid glycine—which was then called glycocolle—might be the amine of a hypothetical acid, which he called "Hydroxyacetic Acid" (acide glycolique).

Hydroxyacetic Acid was first prepared in 1851 by German chemist Adolph Strecker (1822–1871) and Russian chemist Nikolai Nikolaevich Sokolov (1826–1877).
They produced it by treating hippuric acid with nitric acid and nitrogen dioxide to form an ester of benzoic acid and Hydroxyacetic Acid (C6H5C(=O)OCH2COOH), which they called "benzoglycolic acid" (Benzoglykolsäure; also benzoyl glycolic acid).
They boiled the ester for days with dilute sulfuric acid, thereby obtaining benzoic acid and Hydroxyacetic Acid (Glykolsäure).



HYDROXYACETIC ACID VS. INORGANIC ACIDS:
Hydroxyacetic Acid has been replacing mineral acids in multiple applications to avoid the high corrosivity and toxicity of strong inorganic acids.
Hydroxyacetic Acid is commonly used in concrete and masonry cleaners, replacing the long hydrochloric history in this application.
The high penetration and limited damage to the metal surfaces and truck beds make Hydroxyacetic Acid a better option than mineral acids in such applications.



HYDROXYACETIC ACID VS. ORGANIC ACIDS:
Hydroxyacetic Acid has the smallest molecule of the Alpha Hydroxy Acids (AHA) family, so it offers deeper penetration and works faster than other organic acids, including lactic, citric, and maleic acids.

Hydroxyacetic Acid is also preferred over many Beta Hydroxy Acids (BHA) as it provides improved skin moisturization and reduces the visible signs of sun damage and aging wrinkles.
Hydroxyacetic Acid is an excellent choice to replace citric, formic, and acetic acids in industrial applications due to its rapid descaling efficacy combined with superior chelation performance.



CHEMISTRY PROFILE OF HYDROXYACETIC ACID:
Hydroxyacetic Acid is a green acid that is readily biodegradable, VOC-free, and less corrosive than inorganic acids and many other organic acids.



BIODEGRADABLE HYDROXYACETIC ACID: OPINIONS AND BENEFITS:
Many manufacturers believe that powdered Hydroxyacetic Acid, derived from natural sources, is an excellent alternative to aggressive chemicals.
Hydroxyacetic Acid has a very broad range of application; when used in appropriate proportions and conditions, it is not harmful to humans or the environment.

In addition, biodegradable Hydroxyacetic Acid for the face, or a cleaning fluid containing that ingredient, do not increase the amount of toxic waste.
They are only made of raw materials of natural origin, which quickly decompose under the influence of micro-organisms.
Vegetable waste remaining after production can be converted, for example, into compost without occupying any additional space for landfills.



PHYSICAL and CHEMICAL PROPERTIES of HYDROXYACETIC ACID:
Molecular Weight: 76.05 g/mol
XLogP3: -1.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 76.016043985 g/mol
Monoisotopic Mass: 76.016043985 g/mol
Topological Polar Surface Area: 57.5Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 40.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 112 °C (1013 hPa)
Density: 1.26 g/cm3 (20 °C)
Melting Point: 10 °C
pH value: 0.5 (700 g/l, H₂O, 20 °C)
Vapor pressure: 27.5 hPa (25 °C)
Color: colorless liquid
Assay (acidimetric): 69.0 - 74.0 %
Density: (d 20 °C/ 4 °C) 1.260 - 1.280
Heavy metals (as Pb): ≤ 3 ppm
Refractive index (n 20°/D): 1.410 - 1.415
pH-value: 0.0 - 1.0

Chemical formula: C2H4O3
Molar mass: 76.05 g/mol
Appearance: White powder or colorless crystals
Density: 1.49 g/cm3
Melting point: 75 °C (167 °F; 348 K)
Boiling point: Decomposes
Solubility in water: 70% solution
Solubility in other solvents: Alcohols, acetone,
acetic acid and ethyl acetate
log P: −1.05
Acidity (pKa): 3.83

Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 10 °C
Initial boiling point and boiling range 112 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,25 g/mL at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none

Other safety information: No data available
Product name: Glycolic Acid
Other name: Hydroxyacetic Acid
EINECS: 201-180-5
Boiling Point: 112 °C
Purity: 99% White crystal; 70% Yellowish solution
Sample: Free
CAS number: 79-14-1
EC number: 201-180-5
Hill Formula: C₂H₄O₃
Chemical formula: HOCH₂COOH
Molar Mass: 76.05 g/mol

HS Code: 2918 19 98
Boiling point: 100 °C (decomposition)
Density: 1.49 g/cm3 (25 °C)
Flash point: >300 °C (decomposition)
Melting Point: 78 - 80 °C
pH value: 2 (50 g/l, H₂O, 20 °C)
Vapor pressure: 0.00093 hPa (25 °C)
Bulk density: 600 kg/m3
Melting point: 75-80 °C (lit.)
Boiling point: 112 °C
Density: 1.25 g/mL at 25 °C
vapor pressure: 10.8 hPa (80 °C)

refractive index: n20/D 1.424
Flash point: 112°C
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear
pka: 3.83(at 25℃)
form: Solution
color: White to off-white
PH: 2 (50g/l, H2O, 20℃)
Odor: at 100.00 %. odorless very mild buttery
Odor Type: buttery
Viscosity: 6.149mm2/s

Water Solubility: SOLUBLE
Sensitive: Hygroscopic
Merck: 14,4498
BRN: 1209322
Stability: Stable.
Incompatible with bases, oxidizing agents and reducing agents.
InChIKey: AEMRFAOFKBGASW-UHFFFAOYSA-N
LogP: -1.07 at 20℃
Indirect Additives used in Food Contact Substances: GLYCOLIC ACID
FDA 21 CFR: 175.105
CAS DataBase Reference: 79-14-1(CAS DataBase Reference)
EWG's Food Scores: 1-4
NCI Dictionary of Cancer Terms: glycolic acid
FDA UNII: 0WT12SX38S
NIST Chemistry Reference: Acetic acid, hydroxy-(79-14-1)

EPA Substance Registry System: Glycolic acid (79-14-1)
Pesticides Freedom of Information Act (FOIA): Glycolic Acid
Melting Point: 10.0°C
Boiling Point: 113.0°C
Color: Yellow
Linear Formula: CH2OHCOOH
Formula Weight: 76.04
Percent Purity: 70%
Density: 1.2700 g/mL
Physical Form: Solution
Specific Gravity: 1.27
Chemical Name or Material: Glycolic acid, 70% in water

Chemical Formula: C2H4O3
Weight: Average: 76.0514
Monoisotopic: 76.016043994
InChI Key: AEMRFAOFKBGASW-UHFFFAOYSA-N
InChI: InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
CAS number: 79-14-1
IUPAC Name: 2-hydroxyacetic acid
Traditional IUPAC Name: glycolic acid
SMILES: OCC(O)=O
Water Solubility: 608 g/L
logP: -1
logP: -1
logS: 0.9

pKa (Strongest Acidic): 3.53
pKa (Strongest Basic): -3.6
Physiological Charge: -1
Hydrogen Acceptor Count: 3
Hydrogen Donor Count: 2
Polar Surface Area: 57.53 Ų
Rotatable Bond Count: 1
Refractivity: 14.35 m³•mol⁻¹
Polarizability: 6.2 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes



FIRST AID MEASURES of HYDROXYACETIC ACID:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROXYACETIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of HYDROXYACETIC ACID:
-Extinguishing media:
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROXYACETIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROXYACETIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
*Storage class:
Storage class (TRGS 510): 8B:
Non-combustible



STABILITY and REACTIVITY of HYDROXYACETIC ACID:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



HYDROXYACETIC ACID
Hydroxyacetic acid (or Glycolic acid; chemical formula HOCH2CO2H) is a odorless and hygroscopic crystalline solid, highly soluble in water.
Hydroxyacetic acid is a colorless, deliquescent crystals that occur naturally as a component in sugarcane.
Hydroxyacetic acid is the smallest alpha-hydroxy acid (AHA).

CAS Number: 79-14-1
Molecular Formula: C2H4O3
Molecular Weight: 76.05
EINECS Number: 201-180-5

Hydroxyacetic acid is used in various skin-care products.
Hydroxyacetic acid is widespread in nature.
A glycolate (sometimes spelled "glycollate") is a salt or ester of Hydroxyacetic acid.

Hydroxyacetic acid is mainly supplemented to various skin-care products to improve the skin’s appearance and texture.
Hydroxyacetic acid can also reduce wrinkles, acne scarring, and hyperpigmentation.
In textile industry, it can be used as a dyeing and tanning agent.

Hydroxyacetic acid can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.
Hydroxyacetic acid can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss.
Moreover, Hydroxyacetic acid is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.

Hydroxyacetic acid, CH20HCOOH, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF).
Hydroxyacetic acid is soluble in water,alcohol,and ether.
Hydroxyacetic acid is used in dyeing, tanning, electropolishing,and in foodstuffs.

Hydroxyacetic acid is produced by oxidizing glycol with dilute nitric acid.
Hydroxyacetic acid, or glycolic acid, is a weak acid.
Hydroxyacetic acid is sold commercially as a 70% solution.

Hydroxyacetic acid is used in processing and dyeing textiles and Leather.
Hydroxyacetic acid is also used for cleaning, polishing, and soldering metals.
Hydroxyacetic acid is a colorless, odourless, and hygroscopic crystalline solid with the chemical formula C2H4O3.

Hydroxyacetic acid is also known as 2-hydroxyethanoic acid, and its IUPAC name is hydroxyacetic acid.
Hydroxyacetic acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic acid is an alpha hydroxy acid that has antibacterial, antioxidant, keratolytic, and anti-inflammatory properties.

Hydroxyacetic acid is functionally related to acetic acid and is slightly stronger than it.
The salts or esters of Hydroxyacetic acid are called glycolates.
Hydroxyacetic acid is widespread in nature and can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.

Hydroxyacetic acid is widely used in the skincare and cosmetic industry due to its ability to exfoliate the skin, promote skin cell turnover, and improve the overall texture and appearance of the skin.
Hydroxyacetic acid works by breaking down the bonds between dead skin cells on the surface of the skin, allowing them to be sloughed off more easily.
This process can help with various skin concerns, including acne, fine lines and wrinkles, hyperpigmentation, and uneven skin tone.

Hydroxyacetic acid, also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.
These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroxyacetic acid is an extremely weak basic (essentially neutral) compound (based on its pKa).

Hydroxyacetic acid exists in all living species, ranging from bacteria to humans.
In humans, Hydroxyacetic acid is involved in rosiglitazone metabolism pathway.
Outside of the human body, Hydroxyacetic acid has been detected, but not quantified in, several different foods, such as sourdocks, pineappple sages, celeriacs, cloves, and feijoa.

This could make Hydroxyacetic acid a potential biomarker for the consumption of these foods.
Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
Hydroxyacetic acid is a potentially toxic compound.

Hydroxyacetic acid, with regard to humans, has been found to be associated with several diseases such as transurethral resection of the prostate and biliary atresia; Hydroxyacetic acid has also been linked to several inborn metabolic disorders including glutaric acidemia type 2, Hydroxyacetic aciduria, and d-2-hydroxyglutaric aciduria.
Glycolic and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis.

Hydroxyacetic acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.

This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.
Hydroxyacetic acid addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.
Common side effects of Hydroxyacetic acid include dry skin, erythema (skin redness), burning sensation, itching, skin irritation, and skin rash.

Hydroxyacetic acid can make the skin more sensitive in the sunlight, hence always use sunscreen and protective clothing before you step outdoors.
Plants produce Hydroxyacetic acid during photorespiration.
Hydroxyacetic acid is recycled by conversion to glycine within the peroxisomes and to tartronic acid semialdehyde within the chloroplasts.

Hydroxyacetic acid (or hydroxyacetic acid) is the smallest alpha-hydroxy acid (AHA).
This colourless, odourless, and hygroscopic crystalline solid is highly soluble in water.
Due to its excellent capability to penetrate skin, Hydroxyacetic acid is often used in skin care products, most often as a chemical peel.

Hydroxyacetic acid may reduce wrinkles, acne scarring, and hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis.
Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
This allows the outer skin to dissolve, revealing the underlying skin.

Hydroxyacetic acid is thought that this is due to the reduction of calcium ion concentrations in the epidermis and the removal of calcium ions from cell adhesions, leading to desquamation.
Hydroxyacetic acid is a known inhibitor of tyrosinase.
This can suppress melanin formation and lead to a lightening of skin colour.

Acute doses of Hydroxyacetic acid on skin or eyes leads to local effects that are typical of a strong acid (e.g. dermal and eye irritation).
Glycolate is a nephrotoxin if consumed orally.
A nephrotoxin is a compound that causes damage to the kidney and kidney tissues.

Hydroxyacetic acid's renal toxicity is due to its metabolism to oxalic acid.
Glycolic and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis.
Oxalic acid readily precipitates with calcium to form insoluble calcium oxalate crystals.

Renal tissue injury is caused by widespread deposition of oxalate crystals and the toxic effects of Hydroxyacetic acid.
Hydroxyacetic acid does exhibit some inhalation toxicity and can cause respiratory, thymus, and liver damage if present in very high levels over long periods of time.
Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent.

Hydroxyacetic acid is also used in adhesives and plastics.
Hydroxyacetic acid is often included in emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.
Hydroxyacetic acid is used in surface treatment products that increase the coefficient of friction on tile flooring.

Hydroxyacetic acid is the active ingredient in the household cleaning liquid.
Due to its capability to penetrate skin, Hydroxyacetic acid finds applications in skin care products, most often as a chemical peel.
Physician-strength peels can have a pH as low as 0.6 (strong enough to completely keratolyze the epidermis), while acidities for home peels can be as low as 2.5.

Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
This allows the stratum corneum to be exfoliated, exposing live skin cells.
Hydroxyacetic acid is a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.

Hydroxyacetic acid is used as a monomer in the preparation of polyHydroxyacetic acid and other biocompatible copolymers (e.g. PLGA).
Commercially, important derivatives include the methyl and ethyl esters which are readily distillable (boiling points 147–149 °C and 158–159 °C, respectively), unlike the parent acid.
The butyl ester (b.p. 178–186 °C) is a component of some varnishes, being desirable because it is nonvolatile and has good dissolving properties.

Many plants make Hydroxyacetic acid during photorespiration.
Hydroxyacetic acids role consumes significant amounts of energy.
In 2017 researchers announced a process that employs a novel protein to reduce energy consumption/loss and prevent plants from releasing harmful ammonia.

The process converts glycolate into glycerate without using the conventional BASS6 and PLGG1 route.
Hydroxyacetic acid is a water-soluble alpha hydroxy acid (AHA) that is derived from sugar cane.
Hydroxyacetic acid is one of the most well-known and widely used alphahydroxy acids in the skincare industry.

Other alpha-hydroxy acids include lactic acid, malic acid, tartaric acid, and citric acid.
Hydroxyacetic acid has the smallest sized molecules of all the alpha-hydroxy acids Because of these super tiny molecules, Hydroxyacetic acid can easily penetrate the skin.
This allows Hydroxyacetic acid to exfoliate the skin more effectively than other AHAs.

Hydroxyacetic acid works by speeding up cell turnover It helps dissolve the bonds that hold skin cells together, allowing dead skin cells to slough off more rapidly than they would on their own.
Hydroxyacetic acid also stimulates your skin to create more collagen.
Collagen is the protein that gives skin its firmness, plumpness, and elasticity.

Hydroxyacetic acid is an incredibly popular treatment because of the many benefits it has for the skin.
Hydroxyacetic acid has effective skin-renewing properties, so it is often used in anti-aging products.
Hydroxyacetic acid can help smooth fine wrinkles and improve the skin's tone and texture.

Hydroxyacetic acid plumps the skin and helps boost hydration levels.
Hydroxyacetic acid provides far greater solubility than silicafluorides or hydrofluosilicic acid.
Electrochemical Energy Systems permits higher concentrations of acid in solution than citric acid for greater neutralizing efficiency while avoiding salting or rust discoloration problems.

Hydroxyacetic acid reaches a final pH of 5-6 more quickly than silicafluorides, especially at lower wash temperatures.
High solubility means a lower possibility of damaged fabric—even if it’s ironed while wet.
Hydroxyacetic acid liquid doesn’t cake in storage and measures easily out of automatic dispensing equipment.

Hydroxyacetic acid fulfills many roles across a wide range of industries, thanks to its low odor and toxicity, biodegradability, phosphate-free composition, and ability to chelate metal salts.
A glycolate or glycollate is a salt or ester of Hydroxyacetic acid.
(C6H5C(=O)OCH2COOH), which they called "benzoHydroxyacetic acid" (Benzoglykolsäure; also benzoyl Hydroxyacetic acid).

They boiled the ester for days with dilute sulfuric acid, thereby obtaining benzoic acid and Hydroxyacetic acid.
Hydroxyacetic acid can be synthesized in various ways. The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.
Hydroxyacetic acid is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.

Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.
Some of today's Hydroxyacetic acids are formic acid-free.
Hydroxyacetic acid can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.

Hydroxyacetic acid is a simple organic compound with a hydroxyl group (-OH) and a carboxylic acid group (-COOH) on adjacent carbon atoms in its chemical structure.
This gives it its acidic properties.
Hydroxyacetic acid is known for its exfoliating properties.

Hydroxyacetic acid penetrates the skin effectively due to its small molecular size, helping to remove dead skin cells and debris from the surface.
This can lead to a smoother, brighter complexion.
The use of Hydroxyacetic acid in skincare products is associated with several benefits, including reducing the appearance of fine lines and wrinkles, improving skin texture, minimizing the appearance of pores, and fading hyperpigmentation and acne scars.

Hydroxyacetic acid can be used as part of an acne treatment regimen.
Hydroxyacetic acid helps to unclog pores, reduce the formation of comedones (blackheads and whiteheads), and promote the shedding of dead skin cells that can contribute to acne.
Dermatologists often use Hydroxyacetic acid in chemical peels, which are cosmetic procedures designed to improve the skin's appearance.

When using products containing Hydroxyacetic acid, it's important to use sunscreen regularly because Hydroxyacetic acid can increase skin sensitivity to the sun.
Sun protection helps prevent sunburn and further skin damage.
Hydroxyacetic acid can be found in a range of skincare products, including cleansers, toners, serums, and creams.

The concentration of Hydroxyacetic acid in these products can vary, with higher concentrations generally being available in professional treatments.
While Hydroxyacetic acid can benefit many skin types, it may not be suitable for everyone, especially those with very sensitive or reactive skin.

Hydroxyacetic acid's essential to patch test and gradually introduce products containing Hydroxyacetic acid into your skincare routine to monitor how your skin responds.
Hydroxyacetic acid's advisable to consult with a dermatologist or skincare professional.

Melting point: 75-80 °C (lit.)
Boiling point: 112 °C
Density: 1.25 g/mL at 25 °C
vapor pressure: 10.8 hPa (80 °C)
refractive index: n20/D 1.424
Flash point: 112°C
storage temp.: Store below +30°C.
solubility: H2O: 0.1 g/mL, clear
pka: 3.83(at 25℃)
form: Solution
color: White to off-white
PH: 2 (50g/l, H2O, 20℃)
Odor: at 100.00 %. odorless very mild buttery
Odor Type: buttery
Viscosity: 6.149mm2/s
Water Solubility: SOLUBLE
Sensitive: Hygroscopic
Merck: 14,4498
BRN: 1209322
Stability: Stable. Incompatible with bases, oxidizing agents and reducing agents.
InChIKey: AEMRFAOFKBGASW-UHFFFAOYSA-N
LogP: -1.07 at 20℃
Indirect Additives used in Food Contact Substances: Hydroxyacetic acid
FDA 21 CFR: 175.105

Hydroxyacetic acid can be synthesized in various ways.
The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.
Hydroxyacetic acid is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.

Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.
Some of today's Hydroxyacetic acids are formic acid-free.
Hydroxyacetic acid can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.

Hydroxyacetic acid can also be prepared using an enzymatic biochemical process that may require less energy.
For stronger treatments, Hydroxyacetic acid is also utilized in chemical peels available at the salon or dermatologist's office.
Light duty Hydroxyacetic acid peels up to 30% strength can be done by an esthetician at the salon or skin spa.

Stronger peels of up to 70% can be had at the dermatology office.
Skincare products contain other thoughtfully chosen ingredients to give a specific end result.
The Hydroxyacetic acid treatment you choose depends a lot on skin type and what end goals are.

Using low concentrations of Hydroxyacetic acid over long periods of time creates a cumulative effect; skin will look better the longer use.
For treating specific skin issues like noticeable sun damage, dark spots or acne marks, and deeper lines and wrinkles, or for marked improvement of the skin quickly, a professional peel is a good option.
But because peels deliver a higher percentage of Hydroxyacetic acid than daily use products they will be more irritating and have a greater chance of side effects.

When choosing any Hydroxyacetic acid treatment, the percentage of Hydroxyacetic acid is just one factor.
A more acidic product will deliver a stronger and more effective treatment than a less acidic product, regardless of the percentage of Hydroxyacetic acid.
So a product containing a low percentage of Hydroxyacetic acid but with a lower (i.e. more acidic) pH will be more effective than a high percentage but low acidity product.

Unfortunately, the vast majority of skincare products simply list the percentage of Hydroxyacetic acid used.
They are not required to list the pH, so it can make it difficult to compare products apples-to-apples.
Hydroxyacetic acid OTC products and professional peels have been around a long time and have a safe and effective track record.

Most skin types can use them without much trouble.
These aren't quite as irritating as leaveon Hydroxyacetic acid treatments and allow your skin to build up a tolerance without (hopefully) too much irritation.
While Hydroxyacetic acid is a wonderful skincare ingredient.

Hydroxyacetic acid is an Alpha Hydroxy Acid (AHA).
The word acid might scare, but Hydroxyacetic acid usually comes in lower concentrations for at-home use.

It works as an exfoliant to turn over dead skin cells and reveal new skin cells.
It’s also one of the smallest AHAs, meaning that it can penetrate deeply to give the best results.

Hydroxyacetic acid can be used in a skincare routine: as a face wash, as a toner, and as a mask.
Hydroxyacetic acid is the smallest α-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid is highly soluble in water.

Hydroxyacetic acid is found in some sugar-crops.
Hydroxyacetic acid is one of the most well-known and widely used alpha-hydroxy acids in the skincare industry.
Hydroxyacetic acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.

The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.

Hydroxyacetic acid enhances cleaning and descaling processes in oil field and petroleum refining applications.
This acid also provides metal complexing in a biodegradable form without adding undesirable biological or chemical oxygen demand to formulated products.

Hydroxyacetic acid's slower reactivity compared to mineral acids helps with acid finishing during well completion.
Desalting crude oil, well acidizing, and synthetic drilling mud also rely on Hydroxyacetic acid.

Hydroxyacetic acid products for home use typically have lower concentrations (usually ranging from 5% to 20%), while professional treatments may use higher concentrations (up to 70% or more).
Professional treatments are performed by dermatologists or licensed skincare professionals.
When incorporating Hydroxyacetic acid into your skincare routine, it's important to start slowly and gradually increase usage to allow the skin to acclimate.

While Hydroxyacetic acid can be highly effective, it can also cause side effects, especially if used incorrectly or at high concentrations.
Potential side effects include redness, irritation, peeling, and dryness.
These side effects are usually temporary and can be minimized by following product instructions and using moisturizers as needed.

Hydroxyacetic acid is often combined with other skincare ingredients such as hyaluronic acid, antioxidants, and peptides to enhance its benefits and minimize potential irritation.
These combinations can be found in various skincare products to address specific skin concerns.
The pH level of Hydroxyacetic acid products is an important factor in their effectiveness.

Lower pH levels (more acidic) can enhance the exfoliating properties of Hydroxyacetic acid.
Many Hydroxyacetic acid products are formulated at an optimal pH to maximize their exfoliating effects.
Hydroxyacetic acid is often included in anti-aging skincare routines because it can help stimulate collagen production in the skin, leading to improved elasticity and a reduction in the appearance of fine lines and wrinkles over time.

Individuals with certain skin conditions, such as eczema, rosacea, or open wounds, should exercise caution when using Hydroxyacetic acid products, as it can exacerbate these conditions.
Hydroxyacetic acid's advisable to consult with a healthcare professional before use in such cases.
Before using any new skincare product containing Hydroxyacetic acid, it's a good practice to perform a patch test.

Apply a small amount of the product to a discreet area of skin (like the inner forearm) and wait to see if any adverse reactions occur before applying it to face or a larger skin area.
Results may not be immediate, and it may take several weeks to notice significant changes.

History Of Hydroxyacetic acid:
The name "Hydroxyacetic acid" was coined in 1848 by French chemist Auguste Laurent (1807–1853).
He proposed that the amino acid glycine—which was then called glycocolle—might be the amine of a hypothetical acid, which he called "Hydroxyacetic acid" (acide glycolique).

Hydroxyacetic acid was first prepared in 1851 by German chemist Adolph Strecker (1822–1871) and Russian chemist Nikolai Nikolaevich Sokolov (1826–1877).
They produced it by treating hippuric acid with nitric acid and nitrogen dioxide to form an ester of benzoic acid and Hydroxyacetic acid (C6H5C(=O)OCH2COOH), which they called "benzoHydroxyacetic acid" (Benzoglykolsäure; also benzoyl Hydroxyacetic acid).
They boiled the ester for days with dilute sulfuric acid, thereby obtaining benzoic acid and Hydroxyacetic acid (Glykolsäure).

Uses
Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent.
In the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.

Hydroxyacetic acid is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroxyacetic acid is used as a monomer in the preparation of Poly(lactic-co-Hydroxyacetic acid) (PLGA).
Hydroxyacetic acid reacts with lactic acid to form PLGA using ring-opening co-polymerization.,

PolyHydroxyacetic acid (PGA) is prepared from the monomer Hydroxyacetic acid using polycondensation or ring-opening polymerization.
Hydroxyacetic acid is widely used in skin care products as an exfoliant and keratolytic.
Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent.

Hydroxyacetic acid is used in the processing of textiles, leather, and metals.
Hydroxyacetic acid is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroxyacetic acid reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles.

Hydroxyacetic acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells.
Hydroxyacetic acid also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water.
This occurs in the cellular cement through an activation of Hydroxyacetic acid and the skin’s own hyaluronic acid content.

Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by Hydroxyacetic acid.
As a result, the skin’s own ability to raise its moisture content is increased.
Hydroxyacetic acid is the simplest alpha hydroxyacid (AHA).

Hydroxyacetic acid is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight.
Hydroxyacetic acid is mildly irritating to the skin and mucous membranes if the formulation contains a high Hydroxyacetic acid concentration and/ or a low pH.
Hydroxyacetic acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes.

Hydroxyacetic acid is also used for diminishing the signs of age spots, as well as actinic keratosis.
However, Hydroxyacetic acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles.
Regardless of the G skin type, Hydroxyacetic acid use is associated with softer, smoother, healthier, and younger looking skin.

Hydroxyacetic acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.
Hydroxyacetic acid is a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.
Hydroxyacetic acid is used as a monomer in the preparation of polyHydroxyacetic acid and other biocompatible copolymers (e.g. PLGA).

Commercially, important derivatives include the methyl and ethyl esters which are readily distillable (boiling points 147–149 °C and 158–159 °C, respectively), unlike the parent acid.
The butyl ester is a component of some varnishes, being desirable because it is nonvolatile and has good dissolving properties.
Hydroxyacetic acid can be used with hydrochloric or sulfamic acids to prevent iron precipitation in cleaning operations or water flooding.

Hydroxyacetic acid also effectively eliminates harmful deposits while minimizing corrosion damage to steel or copper systems.
Hydroxyacetic acid reacts more slowly and thus penetrates more deeply into formations before fully reacting.
That characteristic leads to enhanced worm holing, because Hydroxyacetic acid dissolves the equivalent amount of calcium carbonate (CaCO₃) as hydrochloric acid without the resulting corrosion.

One of the primary uses of Hydroxyacetic acid in skincare is as an exfoliant.
Hydroxyacetic acid helps remove dead skin cells from the surface of the skin, resulting in a smoother and more radiant complexion.
Hydroxyacetic acid is used to treat acne by unclogging pores, reducing the formation of comedones (blackheads and whiteheads), and promoting the shedding of dead skin cells that can contribute to acne.

Hydroxyacetic acid is commonly used in anti-aging products to stimulate collagen production, which can improve skin elasticity and reduce the appearance of fine lines and wrinkles.
Hydroxyacetic acid can help fade dark spots, sunspots, and post-inflammatory hyperpigmentation by promoting even skin tone.
Hydroxyacetic acid can improve skin texture, making it feel smoother and look more youthful.

Hydroxyacetic acid can minimize the appearance of enlarged pores.
Hydroxyacetic acid is used in chemical peels, both at home and in dermatologist's offices or skincare clinics.
Chemical peels with Hydroxyacetic acid can be tailored to address various skin concerns, including wrinkles, uneven skin tone, and acne scars.

These peels involve the application of a higher concentration of Hydroxyacetic acid to the skin, followed by exfoliation and skin rejuvenation.
In medicine, Hydroxyacetic acid has been used in wound care products to help promote the healing of minor cuts, abrasions, and surgical incisions.
Hydroxyacetic acid can be used to manage keratosis pilaris, a common skin condition characterized by small, rough bumps on the skin, often found on the arms and thighs.

Some over-the-counter products containing Hydroxyacetic acid are used to soften and help remove calluses and corns on the feet.
In some hair care products, Hydroxyacetic acid may be included to help exfoliate the scalp, remove product buildup, and improve hair texture.
Hydroxyacetic acid can help repair sun-damaged skin by promoting the shedding of damaged skin cells and stimulating the production of healthier, more youthful-looking skin.

Hydroxyacetic acid is often used in products designed for sun-damaged or aging skin.
Hydroxyacetic acid can be used to prevent and treat ingrown hairs, particularly in areas prone to razor bumps and irritation, such as the beard area in men.
Hydroxyacetic acid is sometimes combined with other skincare ingredients like salicylic acid, hyaluronic acid, and retinol to create more comprehensive skincare products that address multiple concerns, such as acne, aging, and hydration.

In addition to over-the-counter products, dermatologists and skincare professionals often use Hydroxyacetic acid in more concentrated forms for in-office treatments like chemical peels and microdermabrasion.
These treatments can provide more immediate and dramatic results but require professional oversight.

While Hydroxyacetic acid is commonly associated with facial skincare, it can also be used on other parts of the body to address issues like keratosis pilaris, rough skin on elbows and knees, and body acne.
Hydroxyacetic acid may be used to adjust the pH level of the product.
This can help optimize the effectiveness of other active ingredients.

Hydroxyacetic acid can also act as a humectant, meaning it can attract and retain moisture in the skin, which is beneficial for individuals with dry or dehydrated skin.
However, it's essential to use moisturizers alongside Hydroxyacetic acid products to prevent excessive dryness.
In industrial and household applications, Hydroxyacetic acid is sometimes used to remove stains and scale deposits, such as those caused by hard water, rust, or mineral buildup.

When using Hydroxyacetic acid-containing products in your skincare routine, be cautious about mixing them with other active ingredients, especially strong acids like salicylic acid or vitamin C.
Combining certain active ingredients can lead to skin irritation or reduce effectiveness, so it's advisable to consult with a skincare professional for guidance.

Safety Profile:
Hydroxyacetic acid is a strong acid that causes severe skin and eye irritation at high concentrations (70%).
Hydroxyacetic acid is harmful if swallowed, and inhalation may irritate the respiratory tract and lungs.

Synonyms
Hydroxyacetic acid
2-Hydroxyacetic acid
hydroxyacetic acid
79-14-1
Glycollic acid
Hydroxyethanoic acid
Acetic acid, hydroxy-
glycolate
Polyglycolide
Caswell No. 470
Kyselina glykolova
alpha-Hydroxyacetic acid
Kyselina hydroxyoctova
2-Hydroxyethanoic acid
HOCH2COOH
EPA Pesticide Chemical Code 000101
HSDB 5227
NSC 166
Kyselina glykolova [Czech]
AI3-15362
Kyselina hydroxyoctova [Czech]
C2H4O3
Glycocide
GlyPure
BRN 1209322
NSC-166
Acetic acid, 2-hydroxy-
EINECS 201-180-5
UNII-0WT12SX38S
MFCD00004312
GlyPure 70
0WT12SX38S
CCRIS 9474
DTXSID0025363
CHEBI:17497
Hydroxyacetic acid-13C2
.alpha.-Hydroxyacetic acid
GLYCOLLATE
DTXCID105363
NSC166
EC 201-180-5
4-03-00-00571 (Beilstein Handbook Reference)
GLYCOLIC-2,2-D2 ACID
GOA
Hydroxyacetic acid (MART.)
Hydroxyacetic acid [MART.]
C2H3O3-
glycolicacid
Glycolate Standard: C2H3O3- @ 1000 microg/mL in H2O
Hydroxyethanoate
a-Hydroxyacetate
hydroxy-acetic acid
2-Hydroxyaceticacid
alpha-Hydroxyacetate
a-Hydroxyacetic acid
2-hydroxy acetic acid
2-hydroxy-acetic acid
2-hydroxyl ethanoic acid
HO-CH2-COOH
Hydroxyacetic acid solution
bmse000245
WLN: QV1Q
Hydroxyacetic acid [MI]
Hydroxyacetic acid (7CI,8CI)
Hydroxyacetic acid [INCI]
Hydroxyacetic acid [VANDF]
Hydroxyacetic acid, p.a., 98%
Acetic acid, hydroxy- (9CI)
CHEMBL252557
Hydroxyacetic acid [WHO-DD]
Hydroxyacetic acid, Crystal, Reagent
HYDROXYACETIC ACID [HSDB]
BCP28762
Hydroxyacetic acid, >=97.0% (T)
STR00936
Tox21_301298
s6272
STL197955
AKOS000118921
Hydroxyacetic acid, ReagentPlus(R), 99%
CS-W016683
DB03085
HY-W015967
SB83760
CAS-79-14-1
USEPA/OPP Pesticide Code: 000101
NCGC00160612-01
NCGC00160612-02
NCGC00257533-01
FT-0612572
FT-0669047
G0110
G0196
Hydroxyacetic acid 100 microg/mL in Acetonitrile
EN300-19242
Hydroxyacetic acid, SAJ special grade, >=98.0%
C00160
C03547
D78078
Hydroxyacetic acid, Vetec(TM) reagent grade, 98%
HYDROXYACETIC ACID; HYDROXYETHANOIC ACID
Hydroxyacetic acid, BioXtra, >=98.0% (titration)
Q409373
J-509661
F2191-0224
Hydroxyacetic acid; Hydroxyethanoic acid; Glycollic acid
Z104473274
287EB351-FF9F-4A67-B4B9-D626406C9B13
Hydroxyacetic acid, certified reference material, TraceCERT(R)
InChI=1/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5
Hydroxyacetic acid, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%
Hydroxyacetic acid, Pharmaceutical Secondary Standard; Certified Reference Material
O7Z

HYDROXYACETIC ACID
Hydroxyacetic acid (or Glycolic acid; chemical formula HOCH2CO2H) is a colourless, odourless and hygroscopic crystalline solid, highly soluble in water.
Hydroxyacetic acid is widespread in nature.
A glycolate (sometimes spelled "glycollate") is a salt or ester of Hydroxyacetic acid.


CAS Number: 79-14-1
EC-Number: 201-180-5
Chemical Formula: C2H4O3 / HOCH2COOH


Hydroxyacetic acid is the smallest alpha-hydroxy acid.
Hydroxyacetic acid is the smallest α-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid, Hydroxyacetic acid, is highly soluble in water.
A water solution form of Hydroxyacetic acid is also available.


Hydroxyacetic acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.


Hydroxyacetic acid is a compound that naturally occurs in certain fruits, beets, and sugarcane.
In its pure form, Hydroxyacetic acid is odourless and colourless.
Hydroxyacetic acid belongs to a group of acids experts refer to as alpha hydroxy acids (AHAs).
AHAs are popular ingredients in skin care products.


Other types of AHA include:
*citric acid, which is present in citrus fruits
*malic acid, which is present in apples
*lactic acid, which is present in milk


Of these, Hydroxyacetic acid has the smallest molecular structure, which likely allows it to penetrate deeper into the skin.
Hydroxyacetic acid; the chemical formula C2H4O3 (also written as HOCH2CO2H), is the smallest α-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid, Hydroxyacetic acid, is highly soluble in water.
Hydroxyacetic acid is found in some sugar-crops.


A glycolate is a salt or ester of Hydroxyacetic acid.
Hydroxyacetic acid is an extract of sugar cane, sugar beet or grape.
However, 99% of AHAs used in cosmetics come from laboratory synthesis.
Hydroxyacetic acid is the smallest α-hydroxy acid (AHA).


Hydroxyacetic acid appears in the form of a colorless, odorless and hygroscopic crystalline solid that is highly soluble in water and related solvents.
Hydroxyacetic acid is associated with sugar-crops and is isolated from sugarcane, sugar beets, pineapple, canteloupe, and unripe grapes.
Hydroxyacetic acid is a colorless, odourless, and hygroscopic crystalline solid with the chemical formula C2H4O3.


Hydroxyacetic acid is also known as hydroacetic acid, or 2-hydroxyethanoic acid, and its IUPAC name is hydroxyacetic acid.
Hydroxyacetic acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic acid is an alpha hydroxy acid that has antibacterial, antioxidant, keratolytic, and anti-inflammatory properties.
Hydroxyacetic acid is functionally related to acetic acid and is slightly stronger than it.


The salts or esters of Hydroxyacetic acid are called glycolates.
Hydroxyacetic acid is also a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.
Hydroxyacetic acid is the smallest alpha-hydroxy acid (AHA).


Hydroxyacetic acid is mainly supplemented to various skin-care products to improve the skin’s appearance and texture.
Hydroxyacetic acid can also reduce wrinkles, acne scarring, and hyperpigmentation.
In textile industry, Hydroxyacetic acid can be used as a dyeing and tanning agent.
Hydroxyacetic acid is a water-soluble alpha hydroxy acid (AHA) made from sugar cane.


Hydroxyacetic acid is one of the most widely used AHAs in skincare products.
AHAs are natural acids that come from plants.
They consist of tiny molecules that are very easy for your skin to absorb.
This makes them ideal for smoothing fine lines, improving skin texture, and other anti-aging uses.


Hydroxyacetic acid (or hydroxyacetic acid) is the smallest alpha-hydroxy acid (AHA).
This colorless, odorless, and hygroscopic crystalline solid, Hydroxyacetic acid, is highly soluble in water.
Due to its excellent capability to penetrate skin, Hydroxyacetic acid finds applications in skin care products, most often as a chemical peel.


Hydroxyacetic acid may reduce wrinkles, acne scarring, and hyperpigmentation and improve many other skin conditions, including actinic keratosis, hyperkeratosis, and seborrheic keratosis.
Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.


This allows the outer skin to dissolve revealing the underlying skin.
Hydroxyacetic acid is one of the simplest organic compounds, used on a broad scale in contemporary cosmetology and in the chemical industry.
This is because that hydracid has many valuable properties.
AHA acids (alpha hydroxyacids) cover various types of popular acids that we use on a daily basis.


Examples include citric, lactic or malic acid.
The AHAs also cover Hydroxyacetic acid.
There are several names denoting Hydroxyacetic acid: its chemical name is 2-Hydroxyethanoic acid.
That name was introduced by the International Union of Pure and Applied Chemistry (IUPAC) to facilitate the identification of that substance on a global market.


Hydroxyacetic acid's structural formula is the following: HOCH2COOH.
The molecular formula of Hydroxyacetic acid is: C2H4O3.
Both formulas indicate that the substance contains both carboxyl and the hydroxyl groups, which are typical of alpha-hydroxyacids.
Hydroxyacetic acid is a solid that excellently absorbs water molecules from the environment.


Hydroxyacetic acid is the first member of the series of alpha-hydroxy carboxylic acids, which means it is one of the smallest organic molecules with both acid and alcohol functionality.
Hydroxyacetic acid is combustible but not considered a fire hazard.
Hydroxyacetic acid is soluble in water, alcohol, and ether.


Hydroxyacetic acid 70% (cosmetic grade) is the smallest molecule of the Alpha Hydroxy Acid.
Due to its small size it is able to penetrate the skin, getting into the pores to clear out debris and unclog the pores.
This stimulates new growth of skin and removal of old, dead, dull skin.
Hydroxyacetic acid is a type of alpha hydroxy acid (AHA).


Alpha hydroxy acids are natural acids found in foods.
Hydroxyacetic acid comes from sugarcane.
Alpha hydroxy acids like Hydroxyacetic acid work by removing the top layers of dead skin cells.
Hydroxyacetic acid also seems to help reverse sun damage to the skin.


Don't confuse Hydroxyacetic acid with other alpha hydroxy acids, including citric acid, lactic acid, malic acid, and tartaric acid.
These are not the same.
Hydroxyacetic acid, also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.


These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroxyacetic acid is an extremely weak basic (essentially neutral) compound (based on its pKa).
Hydroxyacetic acid exists in all living species, ranging from bacteria to humans.
In humans, Hydroxyacetic acid is involved in rosiglitazone metabolism pathway.


Outside of the human body, Hydroxyacetic acid has been detected, but not quantified in, several different foods, such as sourdocks, pineappple sages, celeriacs, cloves, and feijoa.
This could make Hydroxyacetic acid a potential biomarker for the consumption of these foods.
Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.


Hydroxyacetic acid is a potentially toxic compound.
Hydroxyacetic acid, with regard to humans, has been found to be associated with several diseases such as transurethral resection of the prostate and biliary atresia; Hydroxyacetic acid has also been linked to several inborn metabolic disorders including glutaric acidemia type 2, glycolic aciduria, and d-2-hydroxyglutaric aciduria.


Hydroxyacetic acid and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis.
Belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.
These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroxyacetic acid is the most commonly used natural AHA (= alpha hydroxy acid).


Hydroxyacetic acid is extracted from sugar cane, grapes and wine leaves.
Biodegradable Hydroxyacetic acid for the face, or a cleaning fluid containing that ingredient, do not increase the amount of toxic waste.
They are only made of raw materials of natural origin, which quickly decompose under the influence of micro-organisms.
Vegetable waste remaining after production can be converted, for example, into compost without occupying any additional space for landfills.


At this point you probably have already heard of Hydroxyacetic acid as it's a staple in the anti skin care world.
Hydroxyacetic acid is also one of the more popular alpha hydroxyl acids used in peeling skin care products.
This type of alpha hydroxyl acid works great at removing dead skin cells and promoting the growth of new collagen and elastin cells.
Hydroxyacetic acid does this by creating microscopic tears in the cells and allowing the firming ingredients in your product to get to the inside of these tears and stimulate the collagen and elastin to grow.


If you are looking for a way to dramatically improve the texture of your skin, you may want to try a Hydroxyacetic acid serum or cream along with a regular application of a high quality cleanser.
Glycolic peels can be applied by using a soft washcloth with warm water.
Glycolic peels can leave your skin very dry so it's important that you only use a small amount.


Applying the product evenly and using a gentle buffing motion while scrubbing into the skin will result in the best results possible.
Be patient as this process may take up to an hour or two depending on how much you've applied.
As with any product you are applying to your skin you should always test a small area first.
If your skin doesn't immediately react to the cream then you may want to wait until you are ready to try it on a larger area of skin.


There are no serious side effects with either regular use or Hydroxyacetic acid peels so don't be afraid to use it as often as you like.
Applying your face only once or twice a day to treat problems with your skin will help you maintain great looking skin.
Remember to also follow the directions on the packaging for proper product use.


Hydroxyacetic acid is also a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.
Hydroxyacetic acid is an organic acid from the family of alpha-hydroxy carboxylic acids that naturally occurs in sugarcane, beets, grapes, and fruits.


Hydroxyacetic acid is the smallest α-hydroxy acid (AHA).
Hydroxyacetic acid appears in the form of a colorless, odorless and hygroscopic crystalline solid that is highly soluble in water and related solvents.
Hydroxyacetic acid is associated with sugar-crops and is isolated from sugarcane, sugar beets, pineapple, canteloupe, and unripe grapes.



USES and APPLICATIONS of HYDROXYACETIC ACID:
Hydroxyacetic acid is used in various skin-care products.
Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative, and in the pharmaceutical industry as a skin care agent.
Hydroxyacetic acid is also used in adhesives and plastics.


Hydroxyacetic acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.
Hydroxyacetic acid is used in surface treatment products that increase the coefficient of friction on tile flooring.
Hydroxyacetic acid is the active ingredient in the household cleaning liquid Pine-Sol.


Cosmetic and pharmaceutical companies include Hydroxyacetic acid in topical products to treat skin conditions or to improve skin texture and appearance.
Hydroxyacetic acid is an alpha hydroxy acid; used in chemical peels and anti-aging skin products.
Hydroxyacetic acid is used in various skin-care products.


Due to its excellent capability to penetrate skin, Hydroxyacetic acid finds applications in skin care products, most often as a chemical peel performed by a dermatologist in concentrations of 20%-80% or at-home kits in lower concentrations of 10%.
Hydroxyacetic acid is used to improve the skin's appearance and texture.
Hydroxyacetic acid may reduce wrinkles, acne scarring, hyperpigmentation and improve many other skin conditions.


Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
This allows the outer skin to "dissolve" revealing the underlying skin.
Hydroxyacetic acid is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).


Among other uses Hydroxyacetic acid finds employment in the textile industry as a dyeing and tanning agent, in food processing as a flavoring agent and as a preservative.
Hydroxyacetic acid is often included into emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.


Hydroxyacetic acid is widespread in nature and can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent.
Hydroxyacetic acid is widely used in skin care products as an exfoliant and keratolytic.


Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent.
Hydroxyacetic acid is used in the processing of textiles, leather, and metals.
Hydroxyacetic acid is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.


Hydroxyacetic acid can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.
Hydroxyacetic acid can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss.
Moreover, Hydroxyacetic acid is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.


Hydroxyacetic acid is used in the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.
Hydroxyacetic acid reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles.


Hydroxyacetic acid acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells.
Hydroxyacetic acid also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water.
This occurs in the cellular cement through an activation of Hydroxyacetic acid and the skin’s own hyaluronic acid content.


Hyaluronic acid is known to retain an impressive amount of moisture and this capacity is enhanced by Hydroxyacetic acid.
As a result, the skin’s own ability to raise its moisture content is increased.
Hydroxyacetic acid is the simplest alpha hydroxyacid (AHA).
Hydroxyacetic acid is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight.


Hydroxyacetic acid is mildly irritating to the skin and mucous membranes if the formulation contains a high Hydroxyacetic acid concentration and/ or a low pH.
Hydroxyacetic acid proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes.
Hydroxyacetic acid is also used for diminishing the signs of age spots, as well as actinic keratosis.


However, Hydroxyacetic acid is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles.
Regardless of the G skin type, Hydroxyacetic acid use is associated with softer, smoother, healthier, and younger looking skin.
Hydroxyacetic acid is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.


Hydroxyacetic acid is used in the textile industry as a dyeing and tanning agent.
Cleaning and washing concentrates with Hydroxyacetic acid quickly remove dirt and microbes from different surfaces.
This is why they are widely used in private homes, industrial plants and public facilities.
Hydroxyacetic acid is also desired by entities from the food, logistic and catering industries.


Hydroxyacetic acid can also be found at schools and kindergartens.
Hydroxyacetic acid is commonly used in chemical milling, cleaning, and polishing of metals, and in copper pickling solutions.
Hydroxyacetic acid is also used in the cosmetic industry in skin peels.
Hydroxyacetic acid 70% (cosmetic grade) is mainly used to improve the appearance and texture of the skin through chemical peel process.


Once applied to the skin Hydroxyacetic acid breaks down the lipids that hold the dead skin cells on the surface, speeding their removal, resulting in an improved appearance with fewer spots, refined pores, and a more even skin tone that is more radiant.
People use Hydroxyacetic acid for acne, aging skin, dark skin patches on the face, and acne scars.
Hydroxyacetic acid is also used for stretch marks and other conditions, but there is no good scientific evidence to support these other uses.


Hydroxyacetic acid consists of tiny molecules that skin absorbs very well.
Hydroxyacetic acid protects collagen and helps your skin shed dead skin cells.
This process smooths and brightens your skin, keeps your pores clean, and prevents ingrown hairs and acne.
Hydroxyacetic acid is not only a popular ingredient in skincare products, it is also used in the textile industry and in food processing as a flavoring agent and a preservative.


Due to its excellent capability to penetrate skin, Hydroxyacetic acid is often used in skin care products, most often as a chemical peel.
Hydroxyacetic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
Hydroxyacetic acid is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).
Among other uses, Hydroxyacetic acid finds employment in the textile industry as a dyeing and tanning agent, in food processing as a flavouring agent and as a preservative.


Hydroxyacetic acid is often included in emulsion polymers, solvents and additives for ink and paint in order to improve flow properties and impart gloss.
Glycolic is a commonly known ingredient in the personal care and cosmetics market and it is also widely used in several household and industrial cleaning applications.


Due to its excellent capability to penetrate skin, Hydroxyacetic acid finds applications in skin care products, most often as a chemical peel performed by a dermatologist in concentrations of 20%-80% or at-home kits in lower concentrations of 10%.
Hydroxyacetic acid is used to improve the skin's appearance and texture.


Hydroxyacetic acid may reduce wrinkles, acne scarring, and hyperpigmentation and improve many other skin conditions.
Once applied, Hydroxyacetic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
This allows the outer skin to "dissolve" revealing the underlying skin.


-Applications of Hydroxyacetic acid:
Today’s drug or household chemical stores offer various types of agents and formulations containing Hydroxyacetic acid.
Their application is very wide.
Hydroxyacetic acid is a component of:
*concentrates designed for the cleaning of Gres tiles, joints and porous surfaces,
*specialised preparations for washing and sterilizing tanks, cisterns, *production lines or equipment having contact with food,
*liquids used for cleaning public sanitary facilities.


-Uses of Hydroxyacetic acid:
*Acid Cleaners
*Concrete Cleaners
*Food Processing
*Hard Surface Cleaners
*Leather-Dyeing and Tanning
*Petroleum Refining
*Textile
*Water Treatment


-Hydroxyacetic acid for Household and Industrial Use:
Hydroxyacetic acid (also known as hydroxyacetic acid) combines a unique set of properties that enables its use across a broad range of applications.
Many of these properties depend on Hydroxyacetic acid's very high affinity for calcium and manganese ions.


-Hydroxyacetic acid enhances cleaning products and increases the efficacy of the cleaning solution's other ingredients.
Offering relatively low corrosion rates with extremely low volatility and excellent ability to cut through hard water salts and scales, Hydroxyacetic acid is:
*Environmentally friendly
*Biodegradable
*Able to clean many surfaces, including concrete, mortar, and various metal
*Readily rinsable
*Completely dilutable
*Compatible with many formulation components


-Hydroxyacetic acid Applications:
*Personal and Skincare Products: ​
Anti-aging creams, acne treatments, exfoliating scrubs, hair conditioners, and other hair care products.
*Household, Institutional, and Industrial Cleaning Products:
Hard surface cleaners, metal cleaners, toilet bowl cleaners, and laundry sours.
*Water Treatment Applications:
Boiler cleaning chemicals, well stimulating solutions, and process cleaning products.


-Hydroxyacetic acid Applications:
*Electronics and Metal Surface Treatment:
Etching chemicals, printed circuit board fluxes, electropolishing chemicals, and metal surface preparations.
*Oil and Gas Applications:
Oil drilling chemicals, well stimulation, mid-and downstream descalers, and general process scale removers.



HYDROXYACETIC ACID FEATURES AND BENEFITS:
*Molecular Size:
Glycolic has a low molecular weight that provides excellent penetration when used in cleaning formulations and personal care products.
*Functionality:
Glycolic has dual functional groups (COOH & OH) that make it act as an acid, descaler, and chelating agent for iron and heavy metals.
*Chemistry profile:
Glycolic acid is a green acid that is readily biodegradable, VOC-free, and less corrosive than inorganic acids and many other organic acids.



HYDROXYACETIC ACID VS. ORGANIC ACIDS:
Hydroxyacetic acid has the smallest molecule of the Alpha Hydroxy Acids (AHA) family, so it offers deeper penetration and works faster than other organic acids, including lactic, citric, and maleic acids.
Hydroxyacetic acid is also preferred over many Beta Hydroxy Acids (BHA) as it provides improved skin moisturization and reduces the visible signs of sun damage and aging wrinkles.
Hydroxyacetic acid is an excellent choice to replace citric, formic, and acetic acids in industrial applications due to its rapid descaling efficacy combined with superior chelation performance.



HYDROXYACETIC ACID VS. INORGANIC ACIDS:
Hydroxyacetic acid has been replacing mineral acids in multiple applications to avoid the high corrosivity and toxicity of strong inorganic acids.
Hydroxyacetic acid is commonly used in concrete and masonry cleaners, replacing the long hydrochloric history in this application.
The high penetration and limited damage to the metal surfaces and truck beds make Hydroxyacetic acid a better option than mineral acids in such applications.

Hydroxyacetic acid is also an excellent alternative to toxic and low penetration acids such as sulfuric, phosphoric, and sulfamic in cleaners, water treatment chemicals, and O&G applications.
Hydroxyacetic acid is preffered nowadays due to its high speed of action, scale removal performance, less corrosivity, biodegredability, and less hazardous waste stream.



PROPERTIES OF HYDROXYACETIC ACID:
Hydroxyacetic acid is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.

Hydroxyacetic acid has the following properties:
*Exfoliative:
As a chemical exfoliant, Hydroxyacetic acid removes the outermost layer of skin cells and oil by dissolving them.
Unlike mechanical exfoliants, such as face scrubs and brushes, Hydroxyacetic acid does not require harsh scrubbing.

*Humectant:
Hydroxyacetic acid is also a humectant, which means it attracts and binds water to skin cells.
Hydroxyacetic acid does this by increasing the synthesis of glycosaminoglycans, which are molecules that draw water in the skin.

*Antibacterial:
A 2020 study states that, at certain concentrations, Hydroxyacetic acid can inhibit the growth of bacteria.
*Anti-aging:
Hydroxyacetic acid can reduce some of the processes that cause visible signs of skin aging.
For example, it can reduce sun damage and increase collagen and hyaluronic acid in the skin.
These substances give skin elasticity and structure.



CHEMICAL PROPERTIES OF HYDROXYACETIC ACID:
Hydroxyacetic acid is used as an intermediate in organic synthesis and several reactions, such as oxidation-reduction, esterification, and long chain polymerization.
Hydroxyacetic acid is used as a monomer in the preparation of Poly(lactic-co-glycolic acid) (PLGA).
Hydroxyacetic acid reacts with lactic acid to form PLGA using ring-opening co-polymerization.
Polyglycolic acid (PGA) is prepared from the monomer Hydroxyacetic acid using polycondensation or ring-opening polymerization.

Glycolic acid, CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF).
Hydroxyacetic acid is soluble in water,alcohol,and ether.
Hydroxyacetic acid is used in dyeing, tanning, electropolishing,and in foodstuffs.
Hydroxyacetic acid is produced by oxidizing glycol with dilute nitric acid.



CHEMICAL AND PHYSICAL PROPERTIES OF HYDROXYACETIC ACID:
How to recognise Hydroxyacetic acid?
The characteristics of that substance are as follows:
Hydroxyacetic acid is a solid having the form of a white or transparent, crystalline, odourless powder.
Hydroxyacetic acid decomposes at 100°C and melts at 80°C.
Hydroxyacetic acid is assumed that Hydroxyacetic acid has a density of 1.49 g/cm³ at around 25°C.
Hydroxyacetic acid is a substance which should be used with particular caution, as it irritates skin, the eye mucosa and respiratory system organs.



BENEFITS OF HYDROXYACETIC ACID FOR THE SKIN:
Hydroxyacetic acid is a substance that chemically exfoliates the skin by dissolving dead skin cells and oils.
Hydroxyacetic acid may also help boost collagen production, and support skin moisture.
Hydroxyacetic acid can remove the very top layer of skin cells without the need for scrubbing.
Hydroxyacetic acid is also useful in treatments for acne, hyperpigmentation, and the visible signs of aging.
However, as with all chemical exfoliants, using Hydroxyacetic acid too frequently, at too high a concentration.

Research suggests that Hydroxyacetic acid may help with the following:
*Acne
Older research from 1999 examined the effect of a peel containing 70% Hydroxyacetic acid on 80 females with acne.
The research found that Hydroxyacetic acid quickly improved all types of acne, particularly comedonal acne, which occurs when pores become clogged with oil and dead skin cells.

It is of note, however, that this strength of Hydroxyacetic acid is only available as a chemical peel.
Over-the-counter (OTC) Hydroxyacetic acid products are not this strong.
Hydroxyacetic acid addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.



HISTORY OF HYDROXYACETIC ACID:
The name "glycolic acid" was coined in 1848 by French chemist Auguste Laurent (1807–1853).
He proposed that the amino acid glycine—which was then called glycocolle—might be the amine of a hypothetical acid, which he called "glycolic acid" (acide glycolique).
Hydroxyacetic acid was first prepared in 1851 by German chemist Adolph Strecker (1822–1871) and Russian chemist Nikolai Nikolaevich Sokolov (1826–1877).
They produced it by treating hippuric acid with nitric acid and nitrogen dioxide to form an ester of benzoic acid and Hydroxyacetic acid (C6H5C(=O)OCH2COOH), which they called "benzoglycolic acid" (Benzoglykolsäure; also benzoyl glycolic acid).
They boiled the ester for days with dilute sulfuric acid, thereby obtaining benzoic acid and glycolic acid (Glykolsäure).



PREPARATION OF HYDROXYACETIC ACID:
Hydroxyacetic acid can be synthesized in various ways.
The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.
Hydroxyacetic acid is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.
Some of today's Hydroxyacetic acids are formic acid-free.
Hydroxyacetic acid can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.
Hydroxyacetic acid can also be prepared using an enzymatic biochemical process that may require less energy.



PREPARATION OF HYDROXYACETIC ACID:
There are different preparation methods to synthesize Hydroxyacetic acid.
However, the most common method is the catalyzed reaction of formaldehyde with synthesis gas, which costs less.
It can be produced when chloroacetic acid reacts with sodium hydroxide and then undergoes re-acidification.

It can also be synthesized by electrolytic reduction of oxalic acid.
Hydroxyacetic acid can be separated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes.
Hydroxyacetic acid can be prepared by hydrolyzing the cyanohydrin that is derived from formaldehyde.

Hydroxyacetic acid is isolated from natural sources and is inexpensively available.
Hydroxyacetic acid can be prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Hydroxyacetic acid can also be prepared using an enzymatic biochemical process which produces fewer impurities compared to traditional chemical synthesis, requires less energy in production and produces less co-product.



ORGANIC SYNTHESIS OF HYDROXYACETIC ACID:
Hydroxyacetic acid is a useful intermediate for organic synthesis, in a range of reactions including: oxidation-reduction, esterification and long chain polymerization.
Hydroxyacetic acid is used as a monomer in the preparation of polyglycolic acid and other biocompatible copolymers (e.g. PLGA).
Commercially, important derivatives include the methyl (CAS# 96-35-5) and ethyl (CAS# 623-50-7) esters which are readily distillable (boiling points 147–149 °C and 158–159 °C, respectively), unlike the parent acid.
The butyl ester (b.p. 178–186 °C) is a component of some varnishes, being desirable because it is nonvolatile and has good dissolving properties.



OCCURRENCE OF HYDROXYACETIC ACID:
Plants produce Hydroxyacetic acid during photorespiration.
Hydroxyacetic acid is recycled by conversion to glycine within the peroxisomes and to tartronic acid semialdehyde within the chloroplasts.
Because photorespiration is a wasteful side reaction with regards to photosynthesis, much effort has been devoted to suppressing its formation.
One process converts glycolate into glycerate without using the conventional BASS6 and PLGG1 route; see glycerate pathway

Hydroxyacetic acid is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic acid has a role as a metabolite and a keratolytic drug.
Hydroxyacetic acid is a 2-hydroxy monocarboxylic acid and a primary alcohol.
Hydroxyacetic acid is functionally related to an acetic acid.
Hydroxyacetic acid is a conjugate acid of a glycolate.



WHAT ELSE DISTINGUISHES HYDROXYACETIC ACID?
The water solubility of that powder is very good and largely depends on the temperature of the liquid: the higher it is, the better the powder will dissolve to form a solution.
Hydroxyacetic acid can also be dissolved in alcohols: ethanol, methanol or acetone.
Hydroxyacetic acid reacts with aluminium and oxidants, which may even cause ignition.



PRODUCTION OF HYDROXYACETIC ACID:
The contemporary cosmetic and chemical markets would be hard to imagine without substances such as AHAs, including Hydroxyacetic acid.
What is this semi-finished product made of?
For decades, various methods of producing C2H4O3 were developed. It can be obtained, for example, by:
A reaction of acetic (chloroacetic) acid derivative with sodium hydroxide (NaOH), which is a strong base.

Obviously, Hydroxyacetic acid will not be produced immediately.
The production of that substance is only possible if the environment of both reacting ingredients is acidified.
A reaction of formaldehyde with water gas (it is one of the most popular methods of the mass production of Hydroxyacetic acid; however, the acquisition of the semi-finished product with this method generates a lot of waste).

Currently there is intensive work carried out on safe and ecological methods of producing hydroxyacetic acids.
Chemists have already developed several new patents, which made it possible to isolate this precious compound from arable crops such as grapevine or sugar cane.
These are highly promising technologies which reduce the consumption and emission of harmful compounds derived from manufacturing processes.



HOW HYDROXYACETIC ACID WORKS:
Hydroxyacetic acid has the smallest-sized molecules of all the AHAs.
This allows Hydroxyacetic acid to absorb into the skin and exfoliate it even better than other AHAs.
Hydroxyacetic acid works by speeding up cell turnover.
In other words, Hydroxyacetic acid dissolves the bonds that hold skin cells together.

In effect, your skin is able to shed dead skin cells more quickly than Hydroxyacetic acid would on its own.
Hydroxyacetic acid triggers your skin to make more collagen as well.
Collagen is the protein that makes skin firm, plump, and elastic.
Hydroxyacetic acid also gives your bones and connective tissues their strength.
Your skin makes less collagen as you age.

Collagen is also destroyed when you spend too much time in the sun.
Using Hydroxyacetic acid each day can help prevent the breakdown of collagen.
What Is Liquid Collagen?
What It Does for Your Skin
Hydroxyacetic acid is a very popular treatment for many reasons, including:1

*Anti-aging:
Hydroxyacetic acid smooths fine wrinkles and improves the skin's tone and texture.
*Hydration:
Hydroxyacetic acid plumps the skin and prevents it from getting dry.

*Sun damage:
Hydroxyacetic acid fades dark patches caused by sun damage and protects collagen from the sun.
*Complexion:
Hydroxyacetic acid brightens the skin when used regularly.

*Exfoliation:
Hydroxyacetic acid prevents ingrown hairs and makes pores appear smaller by helping the skin shed dead skin cells.
*Acne:
Hydroxyacetic acid cleans out pores to prevent comedones, blackheads, and inflamed breakouts.

Although many sources claim Hydroxyacetic acid gets rid of scars, this is one thing it simply can't do.
Hydroxyacetic acid can lighten dark patches left by acne or other wounds.
Hydroxyacetic acid may also soften the look of raised scars and pitted scars, but it will not make them go away.
A better treatment for scars is either a professional strength Hydroxyacetic acid peel or a different scar treatment altogether.



MECHANISM OF ACTION OF HYDROXYACETIC ACID:
Hydroxyacetic acid is a common cosmetic ingredient, which is known for its properties as an exfoliative agent.
Hydroxyacetic acid has anti-inflammatory, antioxidant, and keratolytic effects.
Reportedly, Hydroxyacetic acid has inhibitory effects on UV-induced skin tumorigenesis in the hairless mouse model.
Unfortunately, only a very limited number of studies demonstrate this property of Hydroxyacetic acid.

Hydroxyacetic acid has the lowest molecular weight of all the alpha hydroxy acids, which renders it with the ability to penetrate skin very easily.
There have been two proposed mechanisms by which Hydroxyacetic acid functions.
The first theory is that Hydroxyacetic acid stimulates the epidermis to produce new cells by inducing a mild sub-clinical irritation.

The second theory suggests that Hydroxyacetic acid weakens the intercellular bonding of the corneocytes.
At low concentration (between 2% and 5%), Hydroxyacetic acid enhances progressive weakening of cohesion of the intercellular material (corneodesmosomes) of the stratum corneum, which results in a steady exfoliation of the outermost layers (known as the stratum disjunctum) causing desquamation.

The function of Hydroxyacetic acid is pH dependent.
It can exist as the free acid (protonated form) or glycolate ion (deprotonated form).
In solution, or in formulation, there is an equilibrium that exists between these two species equilibrium reaction between free Hydroxyacetic acid and the ionized form

The free acid form of the molecule (at low pH) is the most biologically active form.
In part, this is believed to stem from the ability of the free acid to more freely penetrate the skin.
The glycolate ion, which normally would be associated with a weak alkali metal, does not have the ability to penetrate into the skin as freely as the free acid form of the molecule.
Therefore, the free acid form has a greater degree of bioavailibity.



WHY IS HYDROXYACETIC ACID INCREASINGLY POPULAR?
Hydroxyacetic acid's effects can be noticed within a few days.
With Hydroxyacetic acid, the epidermis regenerates faster and recovers its natural colour and flexibility.
Hydroxyacetic acid can also be used against discolouration, inflammatory conditions and scars.
Amongst cosmetic ingredients, we can find it under the INCI name Hydroxyacetic acid.



HYDROXYACETIC ACID: OPINIONS
Contemporary consumers search for proven, high-quality chemicals that bring rapid effects and do not cause allergies.
People are increasingly eager to choose natural Hydroxyacetic acid and use cosmetics and chemicals which contain that ingredient.
Hydroxyacetic acid, designed for professional use, is globally recognised as a substitute of many other acids produced artificially.
Industrial plants use C2H4O3, for example, instead of hydrochloric acid which, once used, turns into highly poisonous and hazardous waste.



BIODEGRADABLE HYDROXYACETIC ACID: OPINIONS AND BENEFITS
Many manufacturers believe that powdered Hydroxyacetic acid, derived from natural sources, is an excellent alternative to aggressive chemicals.
Hydroxyacetic acid has a very broad range of application; when used in appropriate proportions and conditions, it is not harmful to humans or the environment.



HYDROXYACETIC ACID IN COSMETICS:
a regenerating glycol for the face and body.
Industrialists and pharmacists discovered long ago that Hydroxyacetic acids are worth using on the face and skin.
They are ingredients of creams, conditioners, shampoos, ointments and tonics as well as additives in washing gels, exfoliation products, etc.
Formulations based on that Hydroxyacetic acid are also used in beauty salons as part of rejuvenating treatments.



EFFECT OF HYDROXYACETIC ACID:
Due to its small molecular size, Hydroxyacetic acid is able to penetrate very deep into the skin.
The powerful exfoliant gets rid of dead skin cells and hydrates the skin at the same time.
Hydroxyacetic acid strengthens the collagen fibers, stimulates cell regeneration, cleanses and minimizes pores and improves small lines and wrinkles.
Hydroxyacetic acid is also great for treating acne.



ALTERNATIVE PARENTS OF HYDROXYACETIC ACID:
*Monocarboxylic acids and derivatives
*Carboxylic acids
*Primary alcohols
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF HYDROXYACETIC ACID:
*Alpha-hydroxy acid
*Monocarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Primary alcohol
*Organooxygen compound
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of HYDROXYACETIC ACID:
Physical state: crystalline
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/range: 75 - 80 °C
Initial boiling point and boiling range: 169 °C at 998 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: > 300 °C - (decomposition)
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: 2 at 50 g/l at 20 °C
Viscosity
Viscosity, kinematic: 6,149 mm2/s at 23 °C
Viscosity, dynamic: No data available
Water solubility: 300 g/l at 22 °C

Partition coefficient: n-octanol/water:
log Pow: < 0,3 at 25 °C
Bioaccumulation is not expected.
Vapor pressure: 0,0041 hPa at 25 °C
Density: 1,26 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Solubility in other solvents:
Methanol: > 1,402 g/l at 22 °C
Surface tension: 57 mN/m at 20 °C
Dissociation constant: 3,1 at 25 °C

Molecular Weight: 76.05
XLogP3: -1.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Exact Mass: 76.016043985
Monoisotopic Mass: 76.016043985
Topological Polar Surface Area: 57.5 Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 40.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: colorless crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 79.50 °C. @ 760.00 mm Hg
Boiling Point: 265.57 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.001000 mmHg @ 25.00 °C. (est)
Flash Point: 264.00 °F. TCC ( 128.70 °C. ) (est)
logP (o/w): -1.204 (est)
Soluble in: alcohol, water, 1e+006 mg/L @ 25 °C (est)

Chemical formula : C2H4O3
IUPAC Name: Hydroxyacetic acid
Molar mass: 76.05 g/mol
Appearance: White powdery solid
Odour: odourless
Density: 1.49 g/cm3
Melting point: 75 °C
Boiling point: Decomposes
Solubility: soluble in water, ether, and alcohols, acetone, and acetic acid
Hydrogen Bond Donor Count : 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 1
Acidity (pKa): 3.83
Melting point: 75-80 °C (lit.)
Boiling point: 112 °C
Density: 1.25 g/mL at 25 °C
vapor pressure: 10.8 hPa (80 °C)
refractive index: n20/D 1.424
Flash point: 112°C
storage temp.: Store below +30°C.

solubility: H2O: 0.1 g/mL, clear
pka: 3.83(at 25℃)
form: Solution
color: White to off-white
PH: 2 (50g/l, H2O, 20℃)
Viscosity: 6.149mm2/s
Water Solubility: SOLUBLE
Sensitive: Hygroscopic
Merck: 14,4498
BRN: 1209322
Stability: Stable.
Min. Purity Spec: 95%
Physical Form (at 20°C): Solid
Melting Point: 72-82°C
Boiling Point: 113°C
Flash Point: >300°C
Density: 1.49
Long-Term Storage: Store long-term in a cool, dry place

Chemical formula: C2H4O3
Molar mass: 76.05 g/mol
Appearance: White powder or colorless crystals
Density: 1.49 g/cm3
Melting point: 75 °C (167 °F; 348 K)
Boiling point: Decomposes
Solubility in water: 70% solution
Solubility in other solvents: Alcohols, acetone, acetic acid and ethyl acetate
log P: −1.05
Acidity (pKa): 3.83
Boiling point: 100 °C
Density: 1.26 g/cm3 (20 °C)
Flash point: >300 °C
Melting Point: 78 - 80 °C
pH value: 2 (50 g/l, H₂O, 20 °C)
Vapor pressure: 0.0041 hPa (25 °C)
Bulk density: 600 kg/m3



FIRST AID MEASURES of HYDROXYACETIC ACID:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROXYACETIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of HYDROXYACETIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROXYACETIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROXYACETIC ACID:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of HYDROXYACETIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
Hydroxyacetic acid
Hydroacetic acid
2-Hydroxyethanoic acid
glycolic acid
2-Hydroxyacetic acid
hydroxyacetic acid
79-14-1
Glycollic acid
Hydroxyethanoic acid
Acetic acid, hydroxy-
glycolate
Caswell No. 470
Glycocide
alpha-Hydroxyacetic acid
Kyselina glykolova
Kyselina hydroxyoctova
HOCH2COOH
2-Hydroxyethanoic acid
Polyglycolide
EPA Pesticide Chemical Code 000101
GlyPure
HSDB 5227
NSC 166
Acetic acid, 2-hydroxy-
AI3-15362
MFCD00004312
GlyPure 70
BRN 1209322
26124-68-5
Glycolic acid solution
NSC-166
Acetic acid, hydroxy-, homopolymer
.alpha.-Hydroxyacetic acid
GLYCOLLATE
0WT12SX38S
NSC166
CHEBI:17497
Polyglycollic acid
GOA
glycolicacid
Dexon (polyester)
Poly(glycolic acid)
Poly(L-glycolic acid)
Glypure 70 homopolymer
Glycolic acid homopolymer
EINECS 201-180-5
UNII-0WT12SX38S
Hydroxyacetic acid homopolymer
Hydroxyethanoate
a-Hydroxyacetate
CCRIS 9474
hydroxy-acetic acid
2-Hydroxyaceticacid
alpha-Hydroxyacetate
a-Hydroxyacetic acid
Acetic acid, 2-hydroxy-, homopolymer
Glycolic Acid 70%
2-hydroxy acetic acid
2-hydroxy-acetic acid
omega-Hydroxy fatty acid
2-hydroxyl ethanoic acid
Glycolic acid, polyesters
HO-CH2-COOH
DSSTox_CID_5363
Hydroxyacetic acid solution
bmse000245
WLN: QV1Q
EC 201-180-5
GLYCOLIC ACID
DSSTox_RID_77763
Glycolic acid (7CI,8CI)
DSSTox_GSID_25363
GLYCOLIC ACID
4-03-00-00571 (Beilstein Handbook Reference)
Glycolic acid, p.a., 98%
GLYCOLIC ACID
Acetic acid, hydroxy- (9CI)
CHEMBL252557
GLYCOLIC ACID
DTXSID0025363
Glycolic Acid, Crystal, Reagent
HYDROXYACETIC ACID
Glycolic acid solution, 56-58%
BCP28762
Glycolic acid, >=97.0% (T)
STR00936
ZINC4658557
Tox21_301298
s6272
STL197955
AKOS000118921
Glycolic acid, ReagentPlus(R), 99%
CS-W016683
DB03085
Glycolic acid solution, puriss., 70%
HY-W015967
SB83760
CAS-79-14-1
NCGC00160612-01
NCGC00160612-02
NCGC00257533-01
Glycolic acid, 66-70% aqueous solution
Glycolic acid solution, CP, 70% in H2O
FT-0612572
FT-0669047
G0110
G0196
Glycolic acid 100 microg/mL in Acetonitrile
EN300-19242
Glycolic acid, SAJ special grade, >=98.0%
C00160
C03547
D78078
Glycolic acid, Vetec(TM) reagent grade, 98%
HYDROXYACETIC ACID
HYDROXYETHANOIC ACID
Glycolic acid, BioXtra, >=98.0% (titration)
Glycolic acid solution, technical, ~55% in H2O
Q409373
J-509661
F2191-0224
Glycolic acid solution, high purity, 70 wt. % in H2O
Hydroxyacetic acid
Hydroxyethanoic acid
Glycollic acid
Z104473274
287EB351-FF9F-4A67-B4B9-D626406C9B13
Glycolic acid solution, technical grade, 70 wt. % in H2O
Glycolic acid, certified reference material, TraceCERT(R)
Glycolic Acid, Pharmaceutical Secondary Standard
2-Hydroxyacetic Acid-13C2
2-Hydroxyethanoic Acid-13C2
GlyPure-13C2
GlyPure 70-13C2
GlyPure 99-13C2
Glycocide-13C2
Hydroxyacetic Acid-13C2
Hydroxyethanoic Acid-13C2
NSC 166-13C2
α-Hydroxyacetic Acid-13C2
&alpha
-hydroxyacetic acid
2-Hydroxy carboxylate
2-Hydroxy carboxylic acid
2-Hydroxyacetate
2-Hydroxyacetic acid
2-Hydroxyethanoate
2-Hydroxyethanoic acid
a-Hydroxyacetate
a-Hydroxyacetic acid
Acetic acid, 2-hydroxy-
2-Hydroxyacetate
2-Hydroxyacetic acid
a-Hydroxyacetate
a-Hydroxyacetic acid
Acetic acid, hydroxy-
alpha-Hydroxyacetate
alpha-Hydroxyacetic acid
Glycocide
Glycolate
Glycolic acid
Glycollate
Glycollic acid
Hydroxyacetate
hydroxyacetic acid
Hydroxyethanoate
Hydroxyethanoic acid
Kyselina glykolova
Kyselina hydroxyoctova
Polyglycolic acid
Sodium glycolate
2-Hydroxyethanoic acid
HOCH2COOH
2-Hydroxyethanoate
Α-hydroxyacetate
Α-hydroxyacetic acid
GlyPure
GlyPure 70
Glycolic acid, 2-(14)C-labeled
Glycolic acid, 1-(14)C-labeled
Glycolic acid, potassium salt
Glycolic acid, monopotassium salt
Glycolic acid, calcium salt
Glycolic acid, monoammonium salt
Glycolic acid, monolithium salt
Glycolic acid, monosodium salt
Potassium glycolate
HYDROXYACETIC ACID (GLYCOLIC ACID)
Hydroxyacetic acid (glycolic acid) is a colorless, odorless and hygroscopic crystalline solid, highly soluble in water.
Hydroxyacetic acid (glycolic acid) is used in various skin-care products.
Hydroxyacetic acid (glycolic acid) is widespread in nature.

CAS: 79-14-1
MF: C2H4O3
MW: 76.05
EINECS: 201-180-5

Hydroxyacetic acid (glycolic acid) is a salt or ester of glycolic acid.
Hydroxyacetic acid (glycolic acid) is the smallest alpha-hydroxy acid (AHA).
Hydroxyacetic acid (glycolic acid) is mainly supplemented to various skin-care products to improve the skin’s appearance and texture.
Hydroxyacetic acid (glycolic acid) can also reduce wrinkles, acne scarring, and hyperpigmentation.
In textile industry, Hydroxyacetic acid (glycolic acid) can be used as a dyeing and tanning agent.
Hydroxyacetic acid (glycolic acid) can also be used as a flavoring agent in food processing, and as a skin care agent in the pharmaceutical industry.
Hydroxyacetic acid (glycolic acid) can also be added into emulsion polymers, solvents and ink additives to improve flow properties and impart gloss.

Moreover, Hydroxyacetic acid (glycolic acid) is a useful intermediate for organic synthesis including oxidative-reduction, esterification and long chain polymerization.
A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
Hydroxyacetic acid (glycolic acid) addresses skin issues by exfoliating dead skin cells that accumulate on the surface of the epidermis and contribute to dull, discolored, and uneven looking skin.
The name "Hydroxyacetic acid (glycolic acid)" was coined in 1848 by French chemist Auguste Laurent (1807–1853).
He proposed that the amino acid glycine—which was then called glycocolle—might be the amine of a hypothetical acid, which he called "Hydroxyacetic acid (glycolic acid)" (acide glycolique).

Hydroxyacetic acid (glycolic acid) was first prepared in 1851 by German chemist Adolph Strecker (1822–1871) and Russian chemist Nikolai Nikolaevich Sokolov (1826–1877).
They produced Hydroxyacetic acid (glycolic acid) by treating hippuric acid with nitric acid and nitrogen dioxide to form an ester of benzoic acid and glycolic acid (C6H5C(=O)OCH2COOH), which they called "benzoglycolic acid" (Benzoglykolsäure; also benzoyl glycolic acid).
They boiled the ester for days with dilute sulfuric acid, there by obtaining benzoic acid and Hydroxyacetic acid (glycolic acid) (Glykolsäure).
Hydroxyacetic acid (glycolic acid) is a 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated. It has a role as a metabolite and a keratolytic drug.
Hydroxyacetic acid (glycolic acid) is a 2-hydroxy monocarboxylic acid and a primary alcohol.
Hydroxyacetic acid (glycolic acid) is functionally related to an acetic acid.
Hydroxyacetic acid (glycolic acid) is a conjugate acid of a glycolate.

Hydroxyacetic acid (glycolic acid), also known as 2-hydroxyacetate or glycolate, belongs to the class of organic compounds known as alpha hydroxy acids and derivatives.
These are organic compounds containing a carboxylic acid substituted with a hydroxyl group on the adjacent carbon.
Hydroxyacetic acid (glycolic acid) is an extremely weak basic (essentially neutral) compound (based on its pKa).
Hydroxyacetic acid (glycolic acid) exists in all living species, ranging from bacteria to humans.
In humans, Hydroxyacetic acid (glycolic acid) is involved in rosiglitazone metabolism pathway.
Outside of the human body, Glycolic acid has been detected, but not quantified in, several different foods, such as sourdocks, pineappple sages, celeriacs, cloves, and feijoa.

This could make Hydroxyacetic acid (glycolic acid) a potential biomarker for the consumption of these foods.
Once applied, glycolic acid reacts with the upper layer of the epidermis, weakening the binding properties of the lipids that hold the dead skin cells together.
Hydroxyacetic acid (glycolic acid) is a potentially toxic compound.
Hydroxyacetic acid (glycolic acid), with regard to humans, has been found to be associated with several diseases such as transurethral resection of the prostate and biliary atresia; Hydroxyacetic acid (glycolic acid) has also been linked to several inborn metabolic disorders including glutaric acidemia type 2, glycolic aciduria, and d-2-hydroxyglutaric aciduria.
Glycolic and oxalic acid, along with excess lactic acid, are responsible for the anion gap metabolic acidosis.

Hydroxyacetic acid (glycolic acid) Chemical Properties
Melting point: 75-80 °C (lit.)
Boiling point: 112 °C
Density: 1.25 g/mL at 25 °C
Vapor pressure: 10.8 hPa (80 °C)
Refractive index: n20/D 1.424
Fp: 112°C
Storage temp.: Store below +30°C.
Solubility H2O: 0.1 g/mL, clear
Pka: 3.83(at 25℃)
Form: Solution
Color: White to off-white
PH: 2 (50g/l, H2O, 20℃)
Odor: at 100.00 %. odorless very mild buttery
Odor Type: buttery
Water Solubility: SOLUBLE
Sensitive: Hygroscopic
Merck: 14,4498
BRN: 1209322
Stability: Stable. Incompatible with bases, oxidizing agents and reducing agents.
InChIKey: AEMRFAOFKBGASW-UHFFFAOYSA-N
LogP: -1.07 at 20℃
CAS DataBase Reference: 79-14-1(CAS DataBase Reference)
NIST Chemistry Reference: Hydroxyacetic acid (glycolic acid)(79-14-1)
EPA Substance Registry System: Hydroxyacetic acid (glycolic acid) (79-14-1)

Hydroxyacetic acid (glycolic acid), CH20HCOOH, also known as hydroxyacetic acid, is composed of colorless deliquescent leaflets that decompose at approximately 78° C (172 OF).
Hydroxyacetic acid (glycolic acid) is soluble in water,alcohol,and ether.
Hydroxyacetic acid (glycolic acid) is used in dyeing, tanning, electropolishing,and in foodstuffs.
Hydroxyacetic acid (glycolic acid) is produced by oxidizing glycol with dilute nitric acid.
Hydroxyacetic acid (glycolic acid) is slightly stronger than acetic acid due to the electron-withdrawing power of the terminal hydroxyl group.
The carboxylate group can coordinate to metal ions forming coordination complexes.
Of particular note are the complexes with Pb2+ and Cu2+ which are significantly stronger than complexes with other carboxylic acids.
This indicates that the hydroxyl group is involved in complex formation, possibly with the loss of its proton.

Uses
In the processing of textiles, leather, and metals; in pH control, and wherever a cheap organic acid is needed, e.g. in the manufacture of adhesives, in copper brightening, decontamination cleaning, dyeing, electroplating, in pickling, cleaning and chemical milling of metals.
Hydroxyacetic acid (glycolic acid) reduces corenocyte cohesion and corneum layer thickening where an excess buildup of dead skin cells can be associated with many common skin problems, such as acne, dry and severely dry skin, and wrinkles.
Hydroxyacetic acid (glycolic acid) acts by dissolving the internal cellular cement responsible for abnormal keratinization, facilitating the sloughing of dead skin cells.
Hydroxyacetic acid (glycolic acid) also improves skin hydration by enhancing moisture uptake as well as increasing the skin’s ability to bind water.

This occurs in the cellular cement through an activation of Hydroxyacetic acid (glycolic acid) and the skin’s own hyaluronic acid content.
Hydroxyacetic acid (glycolic acid) is known to retain an impressive amount of moisture and this capacity is enhanced by glycolic acid.
As a result, the skin’s own ability to raise its moisture content is increased.
Hydroxyacetic acid (glycolic acid) is the simplest alpha hydroxyacid (AHA).
Hydroxyacetic acid (glycolic acid) is also the AHA that scientists and formulators believe has greater penetration potential largely due to its smaller molecular weight.
Hydroxyacetic acid (glycolic acid) is mildly irritating to the skin and mucous membranes if the formulation contains a high glycolic acid concentration and/ or a low pH.
Hydroxyacetic acid (glycolic acid) proves beneficial for acne-prone skin as it helps keep pores clear of excess keratinocytes.

Hydroxyacetic acid (glycolic acid) is also used for diminishing the signs of age spots, as well as actinic keratosis.
However, Hydroxyacetic acid (glycolic acid) is most popularly employed in anti-aging cosmetics because of its hydrating, moisturizing, and skin-normalizing abilities, leading to a reduction in the appearance of fine lines and wrinkles.
Regardless of the G skin type, Hydroxyacetic acid (glycolic acid) use is associated with softer, smoother, healthier, and younger looking skin.
Hydroxyacetic acid (glycolic acid) is naturally found in sugarcane but synthetic versions are most often used in cosmetic formulations.

Preparation
Hydroxyacetic acid (glycolic acid) can be synthesized in various ways.
The predominant approaches use a catalyzed reaction of formaldehyde with synthesis gas (carbonylation of formaldehyde), for its low cost.
Hydroxyacetic acid (glycolic acid) is also prepared by the reaction of chloroacetic acid with sodium hydroxide followed by re-acidification.
Other methods, not noticeably in use, include hydrogenation of oxalic acid, and hydrolysis of the cyanohydrin derived from formaldehyde.
Some of today's Hydroxyacetic acid (glycolic acid) is formic acid-free.
Hydroxyacetic acid (glycolic acid) can be isolated from natural sources, such as sugarcane, sugar beets, pineapple, cantaloupe and unripe grapes.
Hydroxyacetic acid (glycolic acid) can also be prepared using an enzymatic biochemical process that may require less energy.

Side effects
Common side effects of Glycolic acid include dry skin, erythema (skin redness), burning sensation, itching, skin irritation, and skin rash.
Hydroxyacetic acid (glycolic acid) can make the skin more sensitive in the sunlight, hence always use sunscreen and protective clothing before you step outdoors.

Synonyms
glycolic acid
2-Hydroxyacetic acid
hydroxyacetic acid
79-14-1
Glycollic acid
Hydroxyethanoic acid
Acetic acid, hydroxy-
glycolate
Polyglycolide
Caswell No. 470
Kyselina glykolova
alpha-Hydroxyacetic acid
Kyselina hydroxyoctova
2-Hydroxyethanoic acid
HOCH2COOH
EPA Pesticide Chemical Code 000101
HSDB 5227
NSC 166
Kyselina glykolova [Czech]
AI3-15362
Kyselina hydroxyoctova [Czech]
C2H4O3
Glycocide
GlyPure
BRN 1209322
NSC-166
Acetic acid, 2-hydroxy-
EINECS 201-180-5
UNII-0WT12SX38S
MFCD00004312
GlyPure 70
0WT12SX38S
CCRIS 9474
DTXSID0025363
CHEBI:17497
Hydroxyacetic acid-13C2
.alpha.-Hydroxyacetic acid
GLYCOLLATE
DTXCID105363
NSC166
EC 201-180-5
4-03-00-00571 (Beilstein Handbook Reference)
GLYCOLIC-2,2-D2 ACID
GOA
GLYCOLIC ACID (MART.)
GLYCOLIC ACID [MART.]
C2H3O3-
glycolicacid
Glycolate Standard: C2H3O3- @ 1000 microg/mL in H2O
Biofix
Bondek
glycolsyre-
Hydroxyethanoate
SyntheSorb
a-Hydroxyacetate
Acido poliglicolico
hydroxy-acetic acid
2-Hydroxyaceticacid
alpha-Hydroxyacetate
a-Hydroxyacetic acid
26009-03-0
2-hydroxy acetic acid
2-hydroxy-acetic acid
Dexon TC 33
2-hydroxyl ethanoic acid
HO-CH2-COOH
Hydroxyacetic acid solution
bmse000245
D01HNP
UNII-H1IL6F7KB8
WLN: QV1Q
(C2-H2-O2)mult-
GLYCOLIC ACID [MI]
Glycolic acid (7CI,8CI)
GLYCOLIC ACID [INCI]
GLYCOLIC ACID [VANDF]
Glycolic acid, p.a., 98%
Acetic acid, hydroxy- (9CI)
CHEMBL252557
GLYCOLIC ACID [WHO-DD]
Glycolic Acid, Crystal, Reagent
HYDROXYACETIC ACID [HSDB]
Acido poliglicolico [INN-Spanish]
(C2-H4-O3)x-
BCP28762
Glycolic acid, >=97.0% (T)
PHO 3836
STR00936
Tox21_301298
s6272
STL197955
AKOS000118921
Glycolic acid, ReagentPlus(R), 99%
CS-W016683
DB03085
HY-W015967
LS-2184
SB83760
CAS-79-14-1
USEPA/OPP Pesticide Code: 000101
NCGC00160612-01
NCGC00160612-02
NCGC00257533-01
FT-0612572
FT-0669047
G0110
G0196
Glycolic acid 100 microg/mL in Acetonitrile
EN300-19242
Glycolic acid, SAJ special grade, >=98.0%
C00160
C03547
D78078
Glycolic acid, Vetec(TM) reagent grade, 98%
HYDROXYACETIC ACID; HYDROXYETHANOIC ACID
Glycolic acid, BioXtra, >=98.0% (titration)
Q409373
J-509661
F2191-0224
Hydroxyacetic acid; Hydroxyethanoic acid; Glycollic acid
Z104473274
287EB351-FF9F-4A67-B4B9-D626406C9B13
Glycolic acid, certified reference material, TraceCERT(R)
InChI=1/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5
Glycolic acid, anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99%
Glycolic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
Hydroxyanisole butylé ( BHA)- Butylated hydroxyanisole (BHA)
ETHYLPARABEN, N° CAS : 120-47-8 - 4-Hydroxybenzoate d'éthyle, Origine(s) : Synthétique, Nom INCI : ETHYLPARABEN , Nom chimique : Ethyl 4-hydroxybenzoate , N° EINECS/ELINCS : 204-399-4, Additif alimentaire : E214. Ses fonctions (INCI). Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.
Hydroxybenzoate d'éthyle ( ETHYLPARABEN )
HYDROXYBENZOMORPHOLINE, N° CAS : 26021-57-8, Nom INCI : HYDROXYBENZOMORPHOLINE, Nom chimique : 3,4-Dihydro-2H-1,4-benzoxazin-6-ol, N° EINECS/ELINCS : 247-415-5, Classification : Règlementé, Colorant capillaire. Ses fonctions (INCI) : Agent colorant pour cheveux : Colore les cheveux
HYDROXYBENZOMORPHOLINE
HYDROXYCAPRIC ACID, N° CAS : 5393-81-7, Nom INCI : HYDROXYCAPRIC ACID. Nom chimique : Decanoic acid, 2-hydroxy-, (DL)-. Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état
HYDROXYCAPRIC ACID
(2-Hydroxyethyl)(2-hydroxyhexadecyl)dimethylammonium chloride; HYDROXYCETYL HYDROXYETHYL DIMONIUM CHLORIDE
HYDROXYCETYL HYDROXYETHYL DIMONIUM CHLORIDE
HYDROXYCINNAMIC ACID, N° CAS : 7400-08-0, Nom INCI : HYDROXYCINNAMIC ACID, Nom chimique : 4-Hydroxycinnamic acid; 4-Coumaric acid, N° EINECS/ELINCS : 231-000-0, Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état
HYDROXYCINNAMIC ACID
HYDROXYCITRONELLOL, N° CAS : 107-74-4, Nom INCI : HYDROXYCITRONELLOL, Nom chimique : 3,7-Dimethyloctane-1,7-diol, N° EINECS/ELINCS : 203-517-1, Ses fonctions (INCI): Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
HYDROXYCITRONELLOL
Noms français : Diméthyl-3,7 hydroxy-7 octanal-1; Hydroxy-7 citronellal; Hydroxycitronellal. Noms anglais : 1-Octanal, 3,7-dimethyl-7-hydroxy-; 7-Hydroxycitronellal; Hydroxycitronellal; Laurin; HYDROXYCITRONELLAL, N° CAS : 107-75-5 - Hydroxycitronellal, Origine(s) : Synthétique, Autre langue : Hidroxicitronellal, Nom INCI : HYDROXYCITRONELLAL, Nom chimique : 7-Hydroxycitronellal, N° EINECS/ELINCS : 203-518-7, Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques
Hydroxycitronellal ( Laurin )
CALCIUM HYDROXIDE, N° CAS : 1305-62-0 - Hydroxyde de calcium, Nom INCI : CALCIUM HYDROXIDE, Nom chimique : Calcium dihydroxide, N° EINECS/ELINCS : 215-137-3, Additif alimentaire : E526, L'hydroxyde de calcium s'appelle aussi "chaux éteinte" ou encore "chaux hydratée". Cet élément est formé avec de l'eau et de la chaux. L'eau de chaux est l'ingrédient de base indispensable pour la réalisation des liniments oléo-calcaires. On retrouve l'hydroxyde de calcium dans les produits défrisant, il a en effet la capcité à modifier la structure du cheveux : il détruit les liaisons sulfure qui relient les acides aminés dans les mèches des cheveux et modifie leur structure physique. Pour finir, il est aussi utilisé dans certains produits en tant que régulateur de PH, étant à la base très alcalin.Régulateur de pH : Stabilise le pH des cosmétiques
Hydroxyde de calcium
STRONTIUM HYDROXIDE, N° CAS : 18480-07-4 / 1311-10-0 - Hydroxyde de strontium, Nom INCI : STRONTIUM HYDROXIDE, Nom chimique : Strontium hydroxide, N° EINECS/ELINCS : 242-367-1. Classification : Règlementé. Restriction en Europe : III/63. Régulateur de pH pour dépilatoires La concentration maximale autorisée est la suivante : 3,5 % (en strontium), PH <= 12,7 Régulateur de pH : Stabilise le pH des cosmétiques
Hydroxyde de strontium
2-hydroxyethylcelluloseether;ah15; aw15(polysaccharide); aw15[polysaccharide]; bl15; cellosize; The blood coHydroxyethyl cellulose etherngeals the appearance board; Hydroxyethyl cellulose - Viscosity 1500 ~ 2500 CAS NO: 9004-62-0
Hydroxyethyl Cellulose
hydroxyethyl cellulose; Cellulose, hydroxyethyl ether; Hydroxyethylcellulose; 2-Hydroxyethyl cellulose; Hyetellose; Natrosol; Cellosize cas no: 9004-62-0
HYDROXYETHYL CELLULOSE (HEC)
Hydroxyethyl cellulose (HEC) is a non-ionic cellulose ether made through a series of chemical processes, with the natural polymer celluloses as raw materials.
Hydroxyethyl cellulose (HEC) is a nonionic, water-soluble polymer.
Hydroxyethyl cellulose (HEC) is odorless, tasteless, and non-toxic in the shape of white to off-white powders or granules.


CAS Number: 9004-62-0
MDL number: MFCD00072770
E number: E1525 (additional chemicals)


Hydroxyethyl cellulose (HEC) can be dissolved in water to form a transparent viscous solution.
Hydroxyethyl cellulose (HEC) has thickening, adhesion, dispersion, emulsification, film-formation, suspension, absorption, surface activity, salt tolerance, water retention, providing protective colloids and other properties.


Hydroxyethyl Cellulose (HEC) forms a non-ionic gel without the effect of electrolyte, suitable for formulations containing electrolyte.
Hydroxyethyl cellulose (HEC) is a non-ionic, water-soluble polymer derived from cellulose through a series of chemical and physical processes.
Hydroxyethyl cellulose (HEC) is a white to light yellowish, oderless and tastless powder, readily soluble in hot or cold water to form a viscous gel solution.


When pH in solution is within 2 to 12, the solution is quite stable.
Since Hydroxyethyl cellulose (HEC) group is nonionic one in water solution, it won't be reacted with other anions or cations and insensitive to the salts.
But Hydroxyethyl cellulose (HEC) molecule is capable of generating esterification, etherification and acetal reaction, so Hydroxyethyl cellulose (HEC) is possible to make it insoluble in water or improve its properties.


Hydroxyethyl cellulose (HEC)also has good film-forming ability and surface activity.
Hydroxyethyl cellulose (HEC) is a line of nonionic, water-soluble, cellulose based polymers from Dow.
Hydroxyethyl cellulose (HEC) is produced by treating reacting alkali-cellulose with ethylene oxide.


This reaction converts some of the hydroxyl groups on the cellulose polymer to hydroxyethyl groups.
Hydroxyethyl cellulose (HEC) is a white, free-flowing granular powder and is made by reacting ethylene oxide with alkali-cellulose.
Hydroxyethyl cellulose (HEC) is a water-soluble synthetic polymer derived from cellulose in which ethylene oxide groups have been added to the hydroxyl groups.


Hydroxyethyl cellulose (HEC) is a nonionic, water-soluble polymer.
Hydroxyethyl cellulose (HEC) consists of two components: cellulose and hydroxyethyl side chain.
Hydroxyethyl cellulose (HEC) has many properties.


Hydroxyethyl cellulose (HEC) is like water retention, thickening, suspension, anti-microbial, high salt tolerance, and ion/PH insensitivity.
Hydroxyethyl cellulose (HEC) is a non-ionic, water soluble polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
Hydroxyethyl cellulose (HEC) will produce crystal clear gel products and thicken the aqueous phase of cosmetic emulsions.


Hydroxyethyl cellulose (HEC) can be also be used to efficiently thicken shampoos, body washes and shower gels.
One of the problems normally associated with this and other water-soluble thickeners is the tendency of the particles to agglomerate or lump when first wetted with water.
The high-purity cosmetic grade of Hydroxyethyl cellulose (HEC) we offer is an R-grade, designed to be added to water without lumping, and thus greatly facilitating solution preparation.


Hydroxyethyl cellulose (HEC) is also the most efficient grade of non-ionic thickener available from the manufacturer.
Hydration of the R-grade particles has been inhibited.
When the particles are added to water, they disperse without lumping, and following a predetermined delay, begin to dissolve.


This process permits the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.
The inhibition period, from the initial wetting to the start of dissolution, is referred to as the hydration time.


This hydration time can vary from 4-25 min.
Hydration time is markedly affected by two factors: pH and temperature of the water.
A higher temperature and a higher pH decrease the hydration time, but a too high temperature or pH can result in lumping.


So, Hydroxyethyl cellulose (HEC) is recommended that it be added to room temperature water with a neutral pH.
Once hydrated, Hydroxyethyl cellulose (HEC) can be heated and the pH can be adjusted as may be needed.
Hydroxyethyl cellulose (HEC) is an excellent thickening agent for cosmetic and personal care formulations.


This nonionic, water soluble polymer, Hydroxyethyl cellulose (HEC), offers efficient and cost-effective options for making crystal clear gel products.
Hydroxethyl Cellulose (HEC) has an exceptional skin feel and is the perfect ingredient to make crystal clear serums for water soluble active ingredients.
Recommended Percentages of Hydroxyethyl cellulose (HEC):


For Building water phase Viscosity/Stability: 0.1%- 0.5%
For high viscosity crystal clear gel: 1.0%-3.0%
Hydroxyethyl cellulose (HEC) features good water retention and an excellent thickening effect.


Hydroxyethyl cellulose (HEC)'s beneficial to various construction projects.
Hydroxyethyl cellulose (HEC) is derived from cellulose.
Hydroxyethyl cellulose (HEC)'s nature's most abundant biopolymer in plants, wood, and cotton cell walls.
Hydroxyethyl cellulose (HEC) is a gelling and thickening agent derived from cellulose.


Hydroxyethyl cellulose (HEC) is a white, odorless, tasteless, non-toxic, which is often used as a thickener for methyl hydroxyethyl cellulose or hydroxyethyl cellulose grades in industry agent.
Hydroxyethyl cellulose (HEC) is white or light yellowish powder.
Hydroxyethyl cellulose (HEC) is natural colloids derived from natural fiber.


Hydroxyethyl cellulose (HEC) is a water soluble, non-ionic, highly esterified hydroxyethyl cellulose powder.
Hydroxyethyl cellulose (HEC) provides enhanced biostability, very high thickening and water retention, moderate foam stabilization and high solution clarity, gloss appearance, pigment compatibility and pseudoplasticity.


This grade of Hydroxyethyl cellulose (HEC) is particularly well suited for use in interior paints and nonwovens.
Hydroxyethyl cellulose (HEC) is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Hydroxyethyl cellulose (HEC) exhibits high compatibility with other raw materials such as surfactant.


Hydroxyethyl cellulose (HEC) is easily dissolved in cold or hot water to give crystal-clear solutions of varying viscosities.
Hydroxyethyl cellulose (HEC) is nonionic cellulose ether and its solution are more tolerant to the presence of cations,anions and organic solvents.
Hydroxyethyl cellulose (HEC) is bio-degradable,non-toxic and environmental friendly natural product.


Hydroxyethyl cellulose (HEC) is soluble in cold or hot water to give clarified solution.
Hydroxyethyl cellulose (HEC) is a a non-ionic, water-soluble polymer efficient thickening agent and suspending agent.
Hydroxyethyl cellulose (HEC) acts as a thickening and stabilizing agent.


Hydroxyethyl cellulose (HEC) is a nonionic cellulose ether with delayed solubility to ensure a lump free solution in aqueous systems.
Hydroxyethyl cellulose (HEC) exhibits high compatibility with other raw materials such as surfactant.
Hydration time is affected by several factors- pH and temperature of the solution, and concentration level of the Hydroxyethyl cellulose (HEC), and the presence of alkalis like TEA, Sodium hydroxide (pH) solution.


Higher pH and higher temperatures DECREASE hydration time, but the higher pH and temperature adjustments too quickly may result in lumping.
It's recommended that the Hydroxyethyl cellulose (HEC) be added to room temperature water, with a neutral pH.
Once hydrated, Hydroxyethyl cellulose (HEC) can be heated and the pH can be adjusted (typically using TEA) as needed.
(The inhibition period, from the initial wetting to the start of dissolution, hydration time, may vary from 5-25 min)



USES and APPLICATIONS of HYDROXYETHYL CELLULOSE (HEC):
Hydroxyethyl cellulose (HEC) acts as a non-ionic thickening agent.
Hydroxyethyl cellulose (HEC) is easy to use and provides exceptional skin feel, viscosity and stability.
Hydroxyethyl cellulose (HEC) offers efficient and cost-effective options for making crystal clear gel products.


Moreover, Hydroxyethyl cellulose (HEC) easily disperses into room temperature in water without clumping or forming fish-eyes.
Hydroxyethyl cellulose (HEC) is not an emulsifier and will not emulsify oils into water.
Hydroxyethyl cellulose (HEC) finds application in formulating hair styling gels, cosmetic products and personal care formulations.


Hydroxyethyl cellulose (HEC) can be used in building materials, paints industry, petrochemicals, synthetic resin, ceramic industry, pharmaceutical, food, textile, agriculture, cosmetics, tobacco, ink, papermaking and other industries.
Hydroxyethyl cellulose (HEC) is a cellulose ether that is primarily used as a thickener for water-based paint, ink, and adhesive formulations.


Hydroxyethyl cellulose (HEC) grades are defined by their molecular weight or more specifically the viscosity of the aqueous solution that they produce at 2% by weight.
Solutions of low molecular weight Hydroxyethyl cellulose (HEC) grades have a rheology that is near Newtonian and useful for applications that require a stable viscosity regardless of shear.


Solutions of high molecular weight Hydroxyethyl cellulose (HEC), however, behave in a non-Newtonian manner and will have a pseudo-plastic rheology.
This pseudoplasticity makes high viscosity grades of Hydroxyethyl cellulose (HEC) an ideal thickener for latex paint applications where the paint must stay on the brush, yet flow out easily upon brushing.


In addition to its useful nature as a thickening agent, Hydroxyethyl cellulose (HEC) also provides the benefits of a suspension aid, binder, emulsifier, film former, emulsion stabilizer, dispersant, water retention aid, and protective colloid.
Hydroxyethyl cellulose (HEC) offers narrow viscosity ranges, consistent viscosity reproducibility, and excellent solution clarities.


The applications for Hydroxyethyl cellulose (HEC) range but in the industrial space it is primarily used for general thickening applications in latex paints, household cleaners and tape-joint compounds.
Hydroxyethyl cellulose(HEC) is a gelling and thickening agent derived from cellulose.


Hydroxyethyl cellulose (HEC) is non-ionic, water-soluble materials that provide good properties of thickening, suspending, binding, emulsify, film-forming, stabilize, disperse, retain water and etc.
And Hydroxyethyl cellulose (HEC) is widely used in coatings, construction, medicine, food, papermaking and polymer polymerization industry.


In medicine field, Hydroxyethyl cellulose (HEC) and methyl cellulose(MHEC) are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.
Hydroxyethyl cellulose (HEC) has uses in the cosmetics and personal care industries as a gelling and thickening agent.


In pharmaceuticals, cellulose has been used as an adsorbent, glidant, drug solvent, and suspending agent.
Hydroxyethyl cellulose (HEC) is one of the main components of the personal lubricant brand known as K-Y Jelly.
Hydroxyethyl cellulose (HEC) can also be found in household cleaning products.


Hydroxyethyl cellulose (HEC) is suitable for latex paint, oil drilling, adhesives, and personal care.
Hydroxyethyl cellulose (HEC) is mainly used in water-based products.
Hydroxyethyl cellulose (HEC) finds applications as a binder, film former, rheology modifer (thickener), adhesion promoter, dispersion stabilizer, extender and slumping reducer in numerous products including paints, inks, adhesives, cosmetics, personal care products, textiles, cements, ceramics and paper products.


One of the most important applications of Hydroxyethyl cellulose (HEC) and HMHEC are waterborne architectual coatings.
They are either used alone or in combination with other thickeners.
Infact, Hydroxyethyl cellulose (HEC) is the most widely used thickener in exterior latex paints because it is compatible with many coating ingredients such as pigments, surfactants, emulsifiers, preservatives, and binders.


Hydroxyethyl cellulose (HEC) is characterized by the formation of viscous gels in water, useful for making paints, adhesives for construction, as well as in the paper and oil industry, among others.
With good water retention, thickening, suspension properties, Hydroxyethyl cellulose (HEC) offers functional properties and enhance product performancein emulsion-based building materials.


Hydroxyethyl cellulose (HEC) scientific research team specifically for the texture paint, latex paint development of a product, product thickening suspension effect is good, high water retention rate, a small amount of addition, low product unit price can reduce the production cost.
Hydroxyethyl cellulose (HEC) is recommended as thickening agent in water-based paint.


Hydroxyethyl cellulose (HEC) provides excellent thickening efficiency, color development, open time, and superior resistance to biodegradation.
Hydroxyethyl cellulose (HEC) also play a role in the emulsion, dispersion, stability and water retention.
Hydroxyethyl cellulose (HEC) has good rheological properties at different shear rates, and has good workability and leveling, not easy to drop, good splash and sag resistance.


Hydroxyethyl cellulose (HEC) polymer is a hydroxyethyl ether of cellulose, obtained by treating cellulose with sodium hydroxide and reacting with ethylene oxide.
Hydroxyethyl cellulose (HEC) polymers are largely used as water-binder and thickening agent in many industry applications, that is, personal care products, pharmaceutical formulations, building materials, adhesives, etc., and as stabilizer for liquid soaps.


They are available as white free-flowing granular powders that easily dissolve in cold and hot water to give transparent solutions with varying viscosities depending on polymer concentration, type and temperature.
Hydroxyethyl cellulose (HEC) is a non-ionic soluble cellulose ether, soluble in both cold and hot water, thickening, suspension, adhesion, emulsification, film formation, water retention, protective colloids and other properties, used in coatings.


The fluidity and color pigments, emulsion polymers, surfactants, emulsifiers, defoamers and preservatives are widely compatible with slip.
Hydroxyethyl cellulose (HEC) is used to obtain the optimum hydration time to prevent agglomeration caused by accelerators greater than the optimal dissolution rate.
Hydroxyethyl cellulose (HEC) powders consolidate many advantages and contribute to the construction field.


Specifically, they apply in paints and coatings, oil drilling, adhesives and sealants.
Hydroxyethyl cellulose (HEC) is widely used in cosmetics, cleaning solutions, and other household products. Hydroxyethyl cellulose (HEC) and methyl cellulose are frequently used with hydrophobic drugs in capsule formulations, to improve the drugs' dissolution in the gastrointestinal fluids.


This process is known as hydrophilization.
Hydroxyethyl cellulose (HEC) is also used extensively in the oil and gas industry as a drilling mud additive under the name
Hydroxyethyl cellulose (HEC) as well in industrial applications, paint and coatings, ceramics, adhesives, emulsion polymerization, inks, construction, welding rods, pencils and joint fillers.


Hydroxyethyl cellulose (HEC) can be one of the main ingredients in water-based personal lubricants.
Hydroxyethyl cellulose (HEC) is also a key ingredient in the formation of large bubbles as it possesses the ability to dissolve in water but also provide structural strength to the soap bubble.


Among other similar chemicals, Hydroxyethyl cellulose (HEC) is often used as slime (and gunge, in the UK).
Hydroxyethyl cellulose (HEC) is a commonly used thickener in paint&coating formulations.
Hydroxyethyl cellulose (HEC) is used in paint&coating formulations to increase the viscosity of the paint and to improve its flow and leveling properties.


Hydroxyethyl cellulose (HEC) can also be used to make crystal clear, water soluble hair styling gels.
In addition, Hydroxethyl Cellulose (HEC) offers excellent functionality when used in the water phase of emulsions to build viscosity and stability.
However, Hydroxethyl Cellulose (HEC) is not an emulsifier and will not emulsify oils into water.


Hydroxyethyl cellulose (HEC) include antiperspirants & deodorants, conditioners, body care, facial care, styling products, sunscreens, liquid soaps, shave gels and foams, wipes (baby and adult), makeup/mascara, AP/Deodorant solids, and lubricant gels.
Hydroxyethyl cellulose (HEC) is used as a non-ionic cellulose thickener, usually to enhance viscosity, increase concentration by absorbing water, increase viscosity, increase stability, increase degradability, and increase gloss.


Hydroxyethyl cellulose (HEC) is used as a thickener for a series of organic solvents.
Hydroxyethyl cellulose (HEC) is used in various formulations such as film formulations, emulsifiers, flow regulators, and anti-mildew.
Hydroxyethyl cellulose (HEC) is commonly used in the production of water-based resins, the production of interior paints, the adhesive industry, the polymerization of vinyl acetate, the copolymer lactate with vinyl acrylic acid, the hydraulic fracturing process, the production of nonwovens and detergents, cosmetics, Layering of tiles.


In the production of paper, in the production of pet bedding for the production of aqueous polymer emulsions based on ethylene-derived compounds, in the production of pharmaceuticals for the production of various creams and lotions, in the production of toothpaste, in the plastics industry.
Hydroxyethyl cellulose (HEC) enhances the viscosity of drilling fluid.


Hydroxyethyl cellulose (HEC) acts as a thickening and stabilizing agent.
Hydroxyethyl cellulose (HEC) acts as a thickening and stabilizing agent.
Hydroxyethyl cellulose (HEC) is used to thicken shampoos, gels, body washes, and add body and after feel to bubble baths, body care products, lotions and creams.


Hydroxyethyl cellulose (HEC) is used in broad range of applications includes cosmetic & personnel care, Paint & coating, oilfield, construction, etc.
Hydroxyethyl cellulose (HEC) is used as a thickener,binder, stabilizer,film forming, protective colloids and suspending agent.
Hydroxyethyl cellulose (HEC) is used as adhesives, bonding aids, filling cement admixtures


Hydroxyethyl cellulose (HEC) is used as coatings and optical brightener additives, coating polymers, filter control additives
Hydroxyethyl cellulose (HEC) is used as wet strength enhancer, protective colloid, rebound and slip reducing agent, rheology control modifier
Hydroxyethyl cellulose (HEC) is used as a gelling and thickening agent in the development of biological structures for hydrophobic drugs.


Hydroxyethyl cellulose (HEC) is used in rinses, hair conditioner, hair gel and shaving products.
Hydroxyethyl cellulose (HEC) is a hydroxyethyl cellulose powder recommended for use in interior and exterior paints.


-Uses of Hydroxyethyl cellulose (HEC):
*Construction uses of Hydroxyethyl cellulose (HEC): Cement mortar, Concrete mix, Thickening
*Dyeing: Latex paint, polymer emulsifying, Thickening, water retention, retarding
*Papermaking:Sizing agent,Thickener, water-retaining
*Cosmetic:Toothpaste, shampoo, Detergent, Thickener, stabilizer
*Petroleum Oil:Drilling well, completing fluids,Water retention, Thickening,Control of fluid loss


-Recommended fields of application of Hydroxyethyl cellulose (HEC):
*Interior paints
*Exterior paints


-Recommended Field Application of Hydroxyethyl cellulose (HEC):
*Interior paints
*Solid paints
*Exterior paints
*Silicon resin paints
*Tinters
*Glazes


-Application properties of Hydroxyethyl cellulose (HEC):
Hydroxyethyl cellulose (HEC) is majnly recommended for ready mixed joint compounds (RMJC).
Hydroxyethyl cellulose (HEC) provroes a very creamy and easy wôrkability.
Usually Hydroxyethyl cellulose (HEC) is used in combination with Tylose@ MHPC or MHEC grades to Typical data further improve the workability


-Uses of Hydroxyethyl cellulose (HEC):
*solubility
*thickening effect
*surface activity


-Typical recommended for thickening and hydration using Hydroxyethyl cellulose (HEC).
Disperse Hydroxyethyl cellulose in solution, usually water, and by stir vigorously or using a blender.
Continue to hydrate the HEC in water until completely dissolved.
The thickening will be delayed, this is normal and how the product is designed to work. (Stir until all particles are dissolved.
This process allows the preparation of clear, smooth, viscous solutions in a short period of time by simply adding the R-grade to water and stirring until the polymer is completely dissolved to prevent settling of the particles.


-Aplications of Hydroxyethyl cellulose (HEC):
• Paint and coating thickener.
• Preparation of water-based latex paints.
• Preparation and synthesis of binder.
• Extraction of petroleum.
• Construction and building materials.
• Manufacture of paper.
• Binder.
• Adhesive.


-Applications of Hydroxyethyl cellulose (HEC):
*Water-based paint
*Polymerization
*Cosmetics
*Others


-Application Field of Hydroxyethyl cellulose (HEC):
*Interior wall latex paint
*Exterior wall latex paint
*Real stone paint
*Texture paint



FEATURE OF HYDROXYETHYL CELLULOSE (HEC):
*Hydroxyethyl cellulose (HEC) dissolves readily in both cold water and hot water.
*Aqueous solutions of Hydroxyethyl cellulose (HEC) are stable and do not gel at either high or low temperatures.
*Hydroxyethyl cellulose (HEC) is a nonionic cellulose ether that remains chemically and physically stable over a wide pH range.
*Hydroxyethyl cellulose (HEC) shows excellent performance as athickener, as a water-retention agent, as a suspending and dispersing agent, and as a protective colloid.
*Hydroxyethyl cellulose (HEC) can be stored for log periods without degrading significantly, and in aqueous solutions its viscosity remains stable.
*Hydroxyethyl cellulose (HEC) is a water-soluble polymer synthesized by the reaction of ethylene oxide with cellulose.
Aqueous solutions of Hydroxyethyl cellulose (HEC) have excellent characterisstics for applications as thickeners, water-retention agents, suspending and dispersing agents, and as protective colloids.
In the synthesis of hydroxyethylcellulose, the avarage number of moles of ethylene oxide that combines with each mole of cellulose (MS) is used as an index.
The value of MS in Hydroxyethyl cellulose (HEC) is controlled within 1.5 to 2.5.



PROPERTIES AND FUNCTIONALITY OF HYDROXYETHYL CELLULOSE (HEC):
*Benefit from the non-anionic nature, Hydroxyethyl cellulose (HEC) is high stable to broad range of salt, soluble and high resistance even in high brine concentration.
*High-performance thickening, efficient high viscosity build up
*Outstanding pseudoplasticity, Unique shear-thinning characteristic and viscosity reversible
*Film-forming agent, protective colloid action.
*Water retention,maintain water content at formulation
*Excellent compatibility to broad range of water soluble materials or ingredients



IMPORTANT PROPERTIES OF HYDROXYETHYL CELLULOSE (HEC):
Hydroxyethyl cellulose (HEC) can be used as a non-ionic surface active agent.
In addition to thickening, suspending, adhesion, emulsifying, film-forming, dispersing, water-retaining and providing protective colloid properties, but also has the following properties.
1. Hydroxyethyl cellulose (HEC) is soluble in hot or cold water, does not precipitate by heat or boiling, and enables it to have a wide range of solubility and viscosity characteristics, as well as non-thermal gelation;
2. Hydroxyethyl cellulose (HEC)’s non-ionic itself and can coexist with a wide range of other water-soluble polymers, surfactants, and salts, a fine colloidal thickener for the solution containing a high concentration of electrolytes;
3. Hydroxyethyl cellulose (HEC)'s water retention capacity is twice as that of methyl cellulose, and it has better flow-regulating property;
4. Hydroxyethyl cellulose (HEC) is stable in viscosity and prevented from mildew.
Hydroxyethyl cellulose (HEC) enables the paint to have good can-opening effects and better leveling properties in construction.



PROPERTIES OF HYDROXYETHYL CELLULOSE (HEC):
Hydroxyethyl cellulose (HEC) is a free-flowing powder or granules that range in color from white to slightly yellowish.
Hydroxyethyl cellulose (HEC) is odorless and tasteless and contains residual moisture determined by the conditions of production, as well as a small amount of residual salts.
Hydroxyethyl cellulose (HEC) can also contain other additives which, for example, regulate the solubility and dispersibility or purposefully influence the development of viscosity.
Depending on the field of application, Hydroxyethyl cellulose (HEC) is offered in unmodified and modified form.
The most important properties of Hydroxyethyl cellulose (HEC):
*solubility
*thickening effect
*surface activity



BENEFITS OF HYDROXYETHYL CELLULOSE (HEC):
Hydroxyethyl cellulose (HEC) is used as a high performance non-ionic thickener, water-retaining aid and rheological additive in all types of water-based paints and surface coatings, adhesives and many other water-based industrial products.
Hydroxyethyl cellulose (HEC) gives these systems excellent rheological properties.
*Additional purification to reduce ash content Excellent salt tolerance
*Imparts slip and lubricity
*Ability to create clear formulations
*Stabilizes emulsion systems
*Surface-treated to aid incorporation into water
*Vegan suitable



PROPERTIES AND APPLICATIONS OF HYDROXYETHYL CELLULOSE (HEC):
Hydroxyethyl cellulose (HEC) is an important non-ionic, water-soluble cellulose derivative.
Hydroxyethyl cellulose (HEC) is a completely odorless, tasteless, and non-toxic white to light-yellow powder that readily dissolves in hot and cold water but is insoluble in most organic solvents.
When dissolved in water, Hydroxyethyl cellulose (HEC) forms a transparent viscous solution which has a non-Newtonian behavior.

The hydroxyl groups of Hydroxyethyl cellulose (HEC) present in the side chains can be reacted with hydrophobic moities to modify the properties of HEC.
For example, attaching polyether chains onto the cellulose (alkoxylation) yields hydrophobically modified Hydroxyethyl cellulose (HEC).
Hydroxyethyl cellulose (HEC) is an associative thickener that forms a reversible three-dimensional supramolecular network in solution through intra- and intermolecular associations of the hydrophobic groups.



PHYSICAL AND CHEMICAL PROPERTIES OF HYDROXYETHYL CELLULOSE (HEC):
Hydroxyethyl cellulose (HEC) is soluble in both cold and hot water, but under normal circumstances does not dissolve in most organic solvents.
When the pH value is within the range of 2-12, the change in viscosity is small, but if beyond this range, the viscosity will decrease.
The surface-treated Hydroxyethyl cellulose (HEC) can be dispersed in cold water without agglomeration, but dissolution rate is slower, and generally it requires about 30 minutes.
With heat or adjusting the pH value to 8-10, it can be rapidly dissolved.



THE MANUFACTURING PROCESS OF HYDROXYETHYL CELLULOSE (HEC) IS AS FOLLOWS:
1. Purify the cellulose.
2. Mix it with sodium hydroxide to form swollen alkaline cellulose.
3. Then react it with ethylene oxide.



SPECIFICATIONS OF HYDROXYETHYL CELLULOSE (HEC):
-Hydroxyethyl cellulose (HEC) provides viscosity at 3,400-5,000 mPa s (cPs) at 1% in water.
- Hydroxyethyl cellulose (HEC) melts and forms a gel at about 70 degrees and dissolves well at pH higher than 7 (use an alkali such as Triethanolamine helps to raise the pH value, after dissolving, can adjust the pH later)
- Hydroxyethyl cellulose (HEC) can be used in formulations that are acidic down to pH 3 and alkaline up to pH 9.
- Hydroxyethyl cellulose (HEC) has no smell



DRILL INTO BETTER OIL PRODUCTION:
Useful in different forms of oil production, Hydroxyethyl cellulose (HEC) is a family of nonionic, water-soluble polymers that can thicken, suspend, bind, stabilize, disperse, form films, emulsify, retain water and provide protective colloid action.
These unique materials can be used to prepare solutions with a wide range of viscosities – including moderate viscosities with normal colloidal properties to maximum viscosities with minimal dissolved solids.

In workover and completion fluids, Hydroxyethyl cellulose (HEC) is a viscosifier.
Hydroxyethyl cellulose (HEC) helps oil producers provide clear, low-solids fluids that help minimize damage to the formation.
Fluids thickened with Hydroxyethyl cellulose (HEC) are easily broken with acid, enzymes or oxidating agents to maximize the potential for hydrocarbon recovery.
In fracturing fluids, Hydroxyethyl cellulose (HEC) materials act as carriers for proppant.

These fluids also can be broken down easily with acid, enzymes or oxidating agents.
Using the low-solids concept, drilling fluids that are formulated with Hydroxyethyl cellulose (HEC) offer increased penetration rates with good borehole stability.
Property-inhibited fluids can be used in drilling medium-to-hard rock formations, as well as heaving or sloughing shales.
In cementing operations, Hydroxyethyl cellulose (HEC) materials reduce hydraulic friction of the slurry and minimize water loss to the formation.



PHYSICAL and CHEMICAL PROPERTIES of HYDROXYETHYL CELLULOSE (HEC):
Appearance Form: powder
Color: beige
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: No data available
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Chemical formula: variable
Molar mass: variable
Melting point: 140 °C (284 °F; 413 K)
Appearance: white or similar to white powder
Moisture(%): Max. 8.0
PH: 6.0-8.5
Apparent Density: 0.30-0.50 g/ml

Type: Interior / Exterior / Solid Paints
Form: Powder
Appearance: white powder
Etherification: high etherification
Particle size: powder
Delayed solubility: yes
Biostability: yes
Viscosity level (according to Höppler): hydroxyethyl cellulose
Viscosity: 4200 - 5500 mPa-s
solution pH: 6-8.5
Moisture content (packed): <6%
Ash (calculated as Na2SO4): <6%
particle size: no more than 10%
Esterification (MS): 2.70
swelling time: 20 minutes.
Bulk densit: 0.45g/l
Lower explosion limits: 30 g/m³
Upper explosion limits:
Density (at 20 °C): 1,1-1,5 g/cm³
Water solubility: (at 20 °C) > 10 g/L

Partition coefficient: log POW < 0
Ignition temperature: > 460 °C
Auto-ignition temperature > 120 °C
Explosive properties The product is considered non-explosive.
Bulk density: 200 - 600 g/l
Conbustion class: 5
Smoulder temperature: 280 °C
pmax: 10 bar
KSt: < 200 bar*m/s
Dust explosion class: ST1
Minimum ignition energy: > 10 mJ
Physical state: Powder
Colour:Whitish
Odour: characteristic
Test method
pH-Value (at 20 °C): 6 - 8 10 g/l
Changes in the physical state
Melting point: n.a.
Initial boiling point and boiling range: n.a.
Flash point: n.a



FIRST AID MEASURES of HYDROXYETHYL CELLULOSE (HEC):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROXYETHYL CELLULOSE (HEC):
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of HYDROXYETHYL CELLULOSE (HEC):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROXYETHYL CELLULOSE (HEC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of HYDROXYETHYL CELLULOSE (HEC):
-Precautions for safe handling:
*Hygiene measures:
General industrial hygiene practice.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of HYDROXYETHYL CELLULOSE (HEC):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
2-Hydroxyethyl cellulose
Cellulose, hydroxyethyl ether
Hydroxyethylcellulose
2-Hydroxyethyl cellulose
Hyetellose
Natrosol
Cellosize
Hydroxyethyl cellulose
HS 100,000 YP2
Cellulose, 2 – hydroxyethyl ether
hydroxyethyl cellulose
Methyl 2-hydroxyethyl cellulose cas no: 9004-62-0
Hydroxyethyl Cellulose,2-hydroxyethylcelluloseether
ah15
aw15(polysaccharide)
aw15[polysaccharide]
bl15
cellosize
Hydroxyethyl cellulose – Viscosity 1500 ~ 2500
5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol


HYDROXYETHYL CETYLDIMONIUM PHOSPHATE
HYDROXYETHYL ETHYLCELLULOSE, N° CAS : 9004-58-4, Nom INCI : HYDROXYETHYL ETHYLCELLULOSE, Classification : Composé éthoxylé, Ses fonctions (INCI), Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : ETHER D'HYDROXY-2 ETHYL CELLULOSE; ETHER D'HYDROXY-2 ETHYLCELLULOSE. Noms anglais : CELLULOSE ETHYL HYDROXYETHYL ETHER; CELLULOSE, ETHYL 2-HYDROXYETHYL ETHER; ETHYL 2-HYDROXYETHYL ETHER CELLULOSE; ETHYL HYDROXY ETHYL CELLULOSE; ETHYL HYDROXYETHYL CELLULOSE; ETHYLHYDROXY ETHYL CELLULOSE; ETHYLHYDROXYETHYL CELLULOSE. Utilisation: Fabrication de produits pharmaceutiques et de laques
HYDROXYETHYL ETHYLCELLULOSE ( ETHER D'HYDROXY-2 ETHYL CELLULOSE )
HYDROXYETHYL UREA, N° CAS : 1320-51-0, Nom INCI : HYDROXYETHYL UREA, Nom chimique : Urea, (2-Hydroxyethyl)-, N° EINECS/ELINCS : 215-304-0, Ses fonctions (INCI) : Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Agent d'entretien de la peau : Maintient la peau en bon état. (hydroxyethyl)urea ; Urea, N-(hydroxyethyl)-; (2-hydroxyethyl)urea; 1-(1-hydroxyethyl)urea
HYDROXYETHYL METACRYLATE (HEMA)
Hydroxyethyl Metacrylate (HEMA) Applications of Hydroxyethyl metacrylate (HEMA) Polyhydroxyethylmethacrylate is hydrophobic; however, when the polymer is subjected to water it will swell due to the molecule's hydrophilic pendant group. Depending on the physical and chemical structure of the polymer, it is capable of absorbing from 10 to 600% water relative to the dry weight. Because of this property, it was one of the first materials to be successfully used in the manufacture of soft contact lenses. When treated with polyisocyanates, poly(Hydroxyethyl metacrylate (HEMA)) makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints. Poly(2-hydroxyethylmethacrylate) Properties of Hydroxyethyl metacrylate (HEMA) Poly(2-hydroxyethylmethacrylate) is an inert, water-stable, nondegradable hydrogel with high transparency. The physical properties of Hydroxyethyl metacrylate (HEMA) (e.g., swelling, stiffness, rheology) can be tuned by varying cross-linking density, incorporating different chemistries through copolymerization, and introducing mesoscopic pores. Specifically, a reduction in cross-linking density results in a softer, more malleable hydrogel that may be better suited for soft tissue regeneration. Moreover, copolymerization with acetic acid, methylmethacrylate, or dextran can adjust the permanence, hydrophilicity, and cellular adhesion in vivo. Finally, the introduction of mesoscopic porogens can facilitate vascular ingrowth, improve cellular attachment, and overcome limited permeability. Although Hydroxyethyl metacrylate (HEMA) is considered nondegradable (which makes it ideally suited for long-term applications in vivo), degradable Hydroxyethyl metacrylate (HEMA) copolymers have been fabricated by the integration of enzymatically susceptible monomers (e.g., dextran) or cross-linking agents. These degradable materials show promise for controlled release of pharmaceuticals and proteins. Applications of Hydroxyethyl metacrylate (HEMA) Due to its excellent optical properties, Hydroxyethyl metacrylate (HEMA) has primarily been used in ophthalmic applications under the generic names etafilcon A and vifilcon A. In addition, it has been examined for controlled release of proteins and drugs, engineering of cardiac tissue, axonal regeneration in spinal cord injury, and replacement of intervertebral discs. However, two limitations of Hydroxyethyl metacrylate (HEMA) are its propensity for calcification and the toxicity of the 2-hydroxyethylmethacrylate monomers. Phase I testing of Hydroxyethyl metacrylate (HEMA) for corneal prostheses (keratoprosthesis) revealed calcium salt deposition within 2.5 years after implantation. At the same time, residual Hydroxyethyl metacrylate (HEMA) monomer can compromise the mechanical properties of the hydrogel, and leach into surrounding tissue with toxic effects Because 2-hydroxyethyl methacrylate is very important in macromolecular chemistry. This paper reviews the main properties of the polymers or copolymers prepared from it by summarizing the information published in articles or patients. The following plan is adopted: Preparation and purification of 2-hydroxyethyl methacrylate Polymerization and copolymerization of 2-hydroxyethyl methacrylate and physical properties Chemical modifications of monomer Chemical modifications of poly-2-hydroxyethyl methacrylate and related copolymers Grafting reactions of polymer or copolymer Applications in biomedical fields The following abbreviations will be used: Hydroxyethyl metacrylate (HEMA) for 2-hydroxyethyl methacrylate (rather than GMA, which is chiefly employed in medical journals) and Hydroxyethyl metacrylate (HEMA) for the corresponding polymers. EGDMA will be used for ethylene glycol dimethacrylate, an impurity synthesized in the preparation of monomer. Hydroxyethyl metacrylate (HEMA) is perhaps the most widely studied and used neutral hydrophilic monomer. The monomer is soluble, its homopolymer is water-insoluble but plasticized and swollen in water. This monomer is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbents for body fluids and lubricious coatings. As a co-monomer with other ester monomers, Hydroxyethyl metacrylate (HEMA) can be used to control hydrophobicity or introduce reactive sites. 2-Hydroxyethyl methacrylate is perhaps the most widely studied and used neutral hydrophilic monomer. The monomer is soluble, its homopolymer is water-insoluble but plasticized and swollen in water. This monomer is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbents for body fluids and lubricious coatings. As a co-monomer with other ester monomers, Hydroxyethyl metacrylate (HEMA) can be used to control hydrophobicity or introduce reactive sites. glycol methacrylate Technical grade: Purity %=min. 97; Acid Content %=max 1.5; EGDMA content %=max 0.2; Color=50 Because 2-hydroxyethyl methacrylate is very important in macromolecular chemistry. This paper reviews the main properties of the polymers or copolymers prepared from it by summarizing the information published in articles or patients. The following plan is adopted: Preparation and purification of 2-hydroxyethyl methacrylate Polymerization and copolymerization of 2-hydroxyethyl methacrylate and physical properties Chemical modifications of monomer Chemical modifications of poly-2-hydroxyethyl methacrylate and related copolymers Grafting reactions of polymer or copolymer Applications in biomedical fields The following abbreviations will be used: Hydroxyethyl metacrylate (HEMA) for 2-hydroxyethyl methacrylate (rather than GMA, which is chiefly employed in medical journals) and Hydroxyethyl metacrylate (HEMA) for the corresponding polymers. EGDMA will be used for ethylene glycol dimethacrylate, an impurity synthesized in the preparation of monomer. method is the reaction of ethylene oxide and methacrylic acid. The Hydroxyethyl metacrylate (HEMA) prepared by these two methods contains impurities in various percentages: e.g., methacrylic acid results from a hydrolysis reaction of Hydroxyethyl metacrylate (HEMA) and EGDMA coming from esterification between methacrylic acid or Hydroxyethyl metacrylate (HEMA) and ethylene glycol. Since Hydroxyethyl metacrylate (HEMA) is a commercial product, it seems more useful to summarize the various purification procedures rather than the numerous works about industrial preparations because the commercial product contains EGDMA and methacrylic acid in monomer proportions. The main procedures use the solubility of Hydroxyethyl metacrylate (HEMA) in water or diethyl ether and its nonsolubility in hexane. EGDMA is soluble in hexane. Therefore, Hydroxyethyl metacrylate (HEMA) is dissolved in four volumes of water and EGDMA is extracted with hexane. Then the aqueous solution of Hydroxyethyl metacrylate (HEMA) is salted to complex methacrylic acid. Hydroxyethyl metacrylate (HEMA) is extracted with diethyl ether, the solution is dried, and Hydroxyethyl metacrylate (HEMA) is distilled under vacuum. The elimination of methacrylic acid can also be carried out by soaking technical Hydroxyethyl metacrylate (HEMA) with anhydrous sodium carbonate and extracting EGDMA with hexane. Then Hydroxyethyl metacrylate (HEMA) is extracted with diethyl ether and distilled as previously described. The use of ion-exchange resins (Amberlyst A 21) is a simple method of elimination of methacrylic acid but the yield is rather poor. N,N'-Dicyclohexylcarbodiimide has also been used for the elimination of methacrylic acid, but variations in the quality of the reagent often outweigh the value of the method. Lastly, extraction of EGDMA with hexane followed by the washing of a dilute solution of Hydroxyethyl metacrylate (HEMA) in water with sodium hydroxyde or sodium bicarbonate and the extraction of Hydroxyethyl metacrylate (HEMA) with chloroform gives, after drying and evaporation of chloroform, a product of high purity for the preparation of resins for optical microscopy. The purity of the monomer can be checked by using vapor-phase chromatography, liquid chromatography, or thin layer chromatography. Detailed distillation procedures to avoid polymerization of Hydroxyethyl metacrylate (HEMA) have been described. Polymerization As for the majority of methacrylic derivatives, Hydroxyethyl metacrylate (HEMA) can be polymerized by radical initiators or by various methods (y-rays, UV, and plasma). When the monomer is purified (without EGDMA, which is a crosslinking product), a soluble polymer can be synthesized, but when the monomer contains even a low percentage of EGDMA, the prepared copolymers produce swollen gels in water and in many other solvents A summary of the main procedures of polymerization is given in Table 1. Syndiotactic Hydroxyethyl metacrylate (HEMA) has been synthesized by UV catalysis at - 40"C, and isotactic Hydroxyethyl metacrylate (HEMA) has been prepared through hydrolysis of poly(benzoxyethy1 methacrylate) which had been synthesized from the corresponding polymers with dibutyl lithium cuprate as catalyst. Physical Properties of Hydroxyethyl metacrylate (HEMA) Because Hydroxyethyl metacrylate (HEMA) has numerous applications in biomedicine, its physical properties have been widely studied. Studies of Diffusion. The permeability of Hydroxyethyl metacrylate (HEMA), used as a membrane for oxygen, has been compared to other macromolecules. The diffusion of water through hydrogels of Hydroxyethyl metacrylate (HEMA), crosslinked with low percentages of EGDMA, has also been studied. The influence of the degree of crosslinking, the diffusion laws, the measurement of the equilibrium constant with water, and a structural study of swollen gels were recently published. Mechanical and Viscoelastic Properties. These properties were summarized in two previous reviews. Composites with crosslinked Hydroxyethyl metacrylate (HEMA) have good elastic properties. The influence of aqueous solutions of sodium chloride on the elasticity of Hydroxyethyl metacrylate (HEMA) has also been studied in relation to its use for optical lenses. Viscometry, Thermal, and Dielectric Properties, and NMR Characterizations. Because the Mark-Houwink parameters in many solvents are well known, the molecular weights of Hydroxyethyl metacrylate (HEMA) can be measured by viscosity. Lastly, in order to use the Hydroxyethyl metacrylate (HEMA) in the biomedical field, the purification of polymer gel has been described. Copolymerization Reactions of Hydroxyethyl metacrylate (HEMA) Copolymerization reactions of this monomer have been studied for its fundamental properties (determination of reactivity ratios, AlfreyPrice parameters) and its applications in various fields. Some examples of block copolymerization with styrene, 2- phenyl-1,2,3-dioxaphospholane, and with macromonomers of polyamine or polyurethane can be cited. Lastly, fundamental studies on the copolymerization of methyl methacrylate with Hydroxyethyl metacrylate (HEMA) and the determination of the composition of its copolymer have been made, and a model of the copolymerization of Hydroxyethyl metacrylate (HEMA) and EDGMA was recently published. Because Hydroxyethyl metacrylate (HEMA) has a primary alcohol function a great number of nucleophilic reactions have been achieved and generally the modified monomer can be polymerized. CHEMICAL MODIFICATIONS OF Hydroxyethyl metacrylate (HEMA) AND RELATED COPOLYMERS A relatively low number of chemical modifications of Hydroxyethyl metacrylate (HEMA) have been registered because chemical modifications of the corresponding monomer as well as its polymerization are easy to achieve. GRAFTING REACTIONS OF POLYMER AND COPOLYMER By using various techniques, the grafting of Hydroxyethyl metacrylate (HEMA) and copolymers prepared with Hydroxyethyl metacrylate (HEMA) as a comonomer has been carried out with natural polymers such as cellulose, dextran, and starch. APPLICATIONS IN BIOMEDICAL FIELDS Because Hydroxyethyl metacrylate (HEMA) can be easily polymerized, possesses a hydrophilic pendant group, and can form hydrogels, an increasing number of applications have been found in various biomedical fields. Although, as previously mentioned, a complete listing of the literature references appears impossible, we have tried to present the main areas of interest for Hydroxyethyl metacrylate (HEMA), either when used alone or in combination with other chemical reagents. 7.1. Irritant and Toxic Effects First of all, the low toxicity of the monomer is widely accepted but few reports are available on the (potent) irritant effects of Hydroxyethyl metacrylate (HEMA). Intradermal injection of crude Hydroxyethyl metacrylate (HEMA) monomer at low concentrations in saline solution (-1%) was found to induce a very mild irritation in the rat, while higher concentrations (up to 20%) were associated with a pronounced reaction. Similar findings were observed with sodium benzoate (an end product of benzoyl peroxide degradation used as a polymerization initiator) emphasizing the irritant role of residues. Hydroxyethyl metacrylate (HEMA) gels implanted into muscles of rats were found to release residual irritant continuously but at a very low rate, thus inducing no cellular reaction. Hydroxyethyl metacrylate (HEMA) used at 0.01-1% concentrations was found to alter the fine structure of cultured cells with quantitative video microscopy. On the other hand, numerous clinical trials, listed hereafter within a specific organ description, have found minimal irritant reactions. Histological Embedding The use of Hydroxyethyl metacrylate (HEMA) in histological practice (i.e., the study of living tissues and cells at the microscopic level) was proposed by Rosenberg and Wichterle (1631. The hydrophilic properties of the monomer permit it to be used as a combined dehydrating agent for the tissues and as an embedding medium for electron microscopy. 2-HYDROXYETHYL METHACRYLATE 15 of pure Hydroxyethyl metacrylate (HEMA) appeared difficult to section, and they had poor resistance under an electron beam. The quality of commercially available Hydroxyethyl metacrylate (HEMA) was reported to vary considerably up to 1965. Copolymers with n-butyl methacrylate or styrene were also found less satisfactory than the epoxy resins. During the last decade, Hydroxyethyl metacrylate (HEMA) has found a new interest in light microscopy. An extensive review was made by Bennett et al. "1. Briefly, Hydroxyethyl metacrylate (HEMA) embedding is favored for light microscopy because: 1) The embedding duration is shorter than for classical methods. Hydroxyethyl metacrylate (HEMA) was used to embed large and very large specimen. 2) Preservation of tissular and cellular structures is far superior to other classical methods. This is due to the adherence of tissue sections onto the microscopic glass slides and because the resin is not removed prior to staining. 3) Sectioning is easier and semithin sections (i.e., 2 to 3 pm in thickness) can be obtained on conventional microtomes with steel or Ralph's glass knives. Furthermore, once cut, the sections spread on water and do not shrink. 4) Numerous staining methods can be performed on Hydroxyethyl metacrylate (HEMA) sections. Classical stains (excepted those having a hydro-alcoholic vehicle which makes the section swell) have been reported to work well, sometimes after minor modifications. Enzymological studies can readily be done, and large amounts of enzymes are preserved. Calcified tissue enzymes have been demonstrated on undecalcified sections. At the present time, several Hydroxyethyl metacrylate (HEMA)-based commercial kits are available. However, the slow hydrolysis of the resin makes it difficult to obtain regular results; the regenerated methacrylic acid appears to combine with basic stains, and small amounts (1.5% or less) impair correct staining by strongly obscuring the background. Several purification methods specially devoted to histotechnology have been designed. Copolymerization with dimethylamino ethyl methacrylate was proposed to complex the carboxylic groups of methacrylic acid. Hydroxyethyl metacrylate (HEMA) alone was repeatedly found to be a poor medium for calcified tissues because the size of the molecule makes it difficult to infiltrate such tissues. Combined with methyl methacrylate (MMA) or various types of aikyl methacrylates or acrylates, Hydroxyethyl metacrylate (HEMA) was shown to provide suitable embedding media. Hydroxyethyl metacrylate (HEMA) is usually polymerized by a redox reaction (benzoyl peroxide and N,N‘-dimethyl aniline), and the method has been used to embed in the cold, thus preserving enzyme activities. MONTHEARD, CHATZOPOULOS, AND CHAPPARD they induce staining artifacts. Other initiators have also been proposed (barbiturate cyclo compounds, butazolidine). Hydroxyethyl metacrylate (HEMA) has been shown to produce better sections when small amounts of crosslinkers are used. We recently showed that Hydroxyethyl metacrylate (HEMA) embedding is an inhomogeneous mechanism and that it varies according to the volume of monomer to be bulk polymerized. Dentistry Synthetic apatitic calcium phosphate cements were prepared with a Hydroxyethyl metacrylate (HEMA) hydrogel containing tetracalcium phosphate and dicalcium phosphate. Hydroxyethyl metacrylate (HEMA) was found to be a highly biocompatible and resorbable material for primary teeth endodontic filling. However, due to its hydrophilicity, Hydroxyethyl metacrylate (HEMA) appeared more useful in dentistry as a bonding reagent between dentine and other types of restorative resins; varying mixtures of Hydroxyethyl metacrylate (HEMA) and glutaraldehyde were investigated. Other bonding complexes using Hydroxyethyl metacrylate (HEMA) have been reported for enamel and dentine. Hydroxyethyl metacrylate (HEMA) was found to be a suitable vehicle for dentin self-etching primers (such as acidic monomers). Other clinical trials have been done with an antiseptic (chlorhexidine) entrapped in a Hydroxyethyl metacrylate (HEMA)/MMA copolymer membrane to develop a controlled release delivery system. However, Hydroxyethyl metacrylate (HEMA) was found unsuitable as a permanent soft lining material for covering the oral mucosa in denture-bearing areas. Immobilization of Molecules and Cells Immobilization implies the entrapment within a polymeric network of a definite "foreign" compound (i.e., an enzyme, a drug, a cell, . . .), whether it is simply confined or grafted onto the polymeric chains. The ability of various drugs to diffuse into polymers may be used in various types of biotechnologies such as membrane separation and drug delivery devices. The prediction of drug solubilities in Hydroxyethyl metacrylate (HEMA) and other polymers has been studied. Immobilization of chloramphenicol in Hydroxyethyl metacrylate (HEMA) hydrogels crosslinked with EGDMA was found to be released upon swelling of the gel in water; the diffusion obeyed Fick's second law. The kinetics of thiamine (vitamin B1) diffusion from previously loaded Hydroxyethyl metacrylate (HEMA) beads was studied at 37.5"C in water. Theophyllin release from an amphiphilic composite made of Hydroxyethyl metacrylate (HEMA) and polyisobutylene was studied from a kinetic point of view. Hydroxyethyl metacrylate (HEMA) membranes are favored as transdermal delivery systems for long-term constant drug delivery. Vidarabine (an antiviral agent) was entrapped to Hydroxyethyl metacrylate (HEMA) membranes and used for transdermal patches: the blood-drug concentrations could be predicted and the permeability coefficient of the membranes could be adjusted by controlling hydration. Similar observations were obtained with progesteron. Nitroglycerin was also entrapped in Hydroxyethyl metacrylate (HEMA) membranes to provide a transdermal delivery system. Synthetic organ substitutes having the capacity to slowly release hormones have been designed: diffusivity of insulin through Hydroxyethyl metacrylate (HEMA) membranes was studied. Because Hydroxyethyl metacrylate (HEMA) hydrogels are hardly degraded in vivo, it was found that entrapment of drugs (testosterone) in a blend of Hydroxyethyl metacrylate (HEMA)/albumin resulted in a slowly degraded matrix with continuous release of the drug. Testicular prosthesis releasing testosterone have been done. Anticancer drugs have been extensively entrapped in matrices of Hydroxyethyl metacrylate (HEMA), thus providing a hard material which can be implanted into the tumor where it delivers higher amounts of drug in situ. 5- Fluorouracil was embedded in Hydroxyethyl metacrylate (HEMA)/bisglycol acrylate copolymer in 3 mm diameter beads which could be implanted subcutaneously. Methotrexate and 3'3'-dibromoaminopterin were absorbed on Hydroxyethyl metacrylate (HEMA) and used as local intratumoral implants in Gardner's lymphosarcoma of the C3H mouse. The effect of crosslinking on the swelling of Hydroxyethyl metacrylate (HEMA) gels (and the drug diffusion coefficient through these gels) has been explored. Finally, various substances have been immobilized in Hydroxyethyl metacrylate (HEMA) in order to prepare diagnostic tools. An antiserum-raised methotrexate was entrapped in Hydroxyethyl metacrylate (HEMA) during polymerization. The lyophilized powder was used for radioimmunoassay of this anticancer drug. The entrapment of immunoglobulins has been used for immunochemical studies. The Fc fragment of immunoglobulins has been grafted onto Separon Hydroxyethyl metacrylate (HEMA) resins after periodate oxidation, thus providing immuno-affinity sorbents for the isolation of proteins. A dye, Cibracron Blue F3GA, was entrapped within the pores of a nylon/ Hydroxyethyl metacrylate (HEMA) gel used for protein purification. Biocompatibility of Hydroxyethyl metacrylate (HEMA) Biocompatibility of Hydroxyethyl metacrylate (HEMA) has been studied at the cell and tissue levels. Cell cultures on Hydroxyethyl metacrylate (HEMA)-coated slides or on Hydroxyethyl metacrylate (HEMA) hydrogels are used to investigate the intimate mechanisms of cellular compatibility. Implanting pieces of gel in an animal by a surgical procedure allows the study of the adverse reactions of the whole organisms against the resin. Because implantations in the eye or in direct contact with blood induces specific problems, these two aspects of the biocompatibility will be treated separately below. Cell Culture The hydrophilicity of the resin was primarily thought to be favorable for cell culture. Cellular adherence to Hydroxyethyl metacrylate (HEMA) has been recognized since 1975 when myoblasts from chicken embryos were cultured on polysiloxane grafted with Hydroxyethyl metacrylate (HEMA). Spreading of cells of hamster kidney was found higher on modified Hydroxyethyl metacrylate (HEMA) than on polystyrene due to the hydrophilic properties of the resin. Similar experiments done with endothelial cells of newborn cords have shown that cells first adhere to the hydrophilic substrate, then spread and proliferate. However, pure and unmodified Hydroxyethyl metacrylate (HEMA) appears unable to support attachment and growth of mammalian cells. Implants Hydroxyethyl metacrylate (HEMA) is a suitable biomaterial for implantation because of its lack of toxicity and high resistance to degradation. Numerous composite biomaterials based on Hydroxyethyl metacrylate (HEMA) and collagen blends have been used. By using various additives, the mechanical properties of Hydroxyethyl metacrylate (HEMA) hydrogels can be adjusted to various biomedical applications. Hydroxyethyl metacrylate (HEMA)/methacrylic acid copolymers were found more biocompatible than Hydroxyethyl metacrylate (HEMA) alone which induces a giant cell inflammatory reaction when implanted. When collagen was entrapped in Hydroxyethyl metacrylate (HEMA) gels, their composites were found highly biocompatible when implanted subcutaneously in rats. Composites with a low collagen content were found to be better preserved in long-term implantation studies whereas those containing higher amounts of collagen exhibited calcification in the early stages, followed by full biodegradation. Calcification of a synthetic biomaterial implies poor biocompatibility. Although the chemical composition appears important, the macroscopic structure and surface characters of a Hydroxyethyl metacrylate (HEMA) implant have been shown to play a key role. 2-HYDROXYETHYL METHACRYLATE 21 of calcification; in addition, hydrogels of Hydroxyethyl metacrylate (HEMA) and methacrylic acid copolymers were found to pick up large amounts of Ca2+ when exposed to aqueous solutions of calcium. This effect was taken into account when porous sponges of Hydroxyethyl metacrylate (HEMA) were compared to demineralized bone for inducing ectopic bone formation. Hydrogels of Hydroxyethyl metacrylate (HEMA) have an excellent biocompatibility but present poor mechanical properties. The mechanical and hydration properties of Hydroxyethyl metacrylate (HEMA) and other polyhydroxyalkyl methacrylate membranes have been studied. Composites of silicone rubber and fine particles of hydrated Hydroxyethyl metacrylate (HEMA) were found to combine both advantages. Radiation grafting of Hydroxyethyl metacrylate (HEMA) was done on polyurethane films (with good mechanical properties) and found to increase hydrophilicity and tolerance. Hydroxyethyl metacrylate (HEMA) was grafted on polyether urethane area membranes used for hemodialysis; permeability and blood tolerance were improved but tensile strength was reduced. Hemodialysis membranes of Hydroxyethyl metacrylate (HEMA) crosslinked with ethylene dimethacrylate have been prepared. The interaction of urea (the end product of protein catabolism) with Hydroxyethyl metacrylate (HEMA) hydrogels revealed that small amounts of methacrylic acid may dramatically increase the swelling properties of the gel. Prosthetic Vascular Implants and Blood Compatibility A very interesting property of Hydroxyethyl metacrylate (HEMA)-based hydrogels is their high hemocompatibility. In the presence of blood, thrombus formation is delayed. Because blood is a complex milieu, in this paragraph we consider all the relationships of Hydroxyethyl metacrylate (HEMA) with blood cells, endothelial cells (i.e., the inner cells of the blood vessels), orland blood components. Due to the hydrophilicity of Hydroxyethyl metacrylate (HEMA), films of styrene-butadiene-styrene had a better blood compatibility when grafted with Hydroxyethyl metacrylate (HEMA). Copolymers of Hydroxyethyl metacrylate (HEMA)/styrene or Hydroxyethyl metacrylate (HEMA)/dimethyl siloxane suppress platelet adhesion and aggregation (and thus reduce thrombus formation) by the creation of hydrophilic/hydrophobic microdomains. Similar findings were obtained with Hydroxyethyl metacrylate (HEMA)/polyethylene oxide and Hydroxyethyl metacrylate (HEMA)/ polypropylene oxide copolymers. A Hydroxyethyl metacrylate (HEMA)-polyamine copolymer was found to induce no blood platelet adherence or activation. Also, this copolymer was used to separate T from B lymphocytes subpopulations via its hydrophilic-hydrophobic microdomain compositio. Vascular tubes of polyethylene Blended with 14% Hydroxyethyl metacrylate (HEMA) have a very low thrombogeneity due to hydrophilization of the plastic. Radiation grafting of Hydroxyethyl metacrylate (HEMA) and N-vinyl pyrrolidone on silicone rubber was used to improve the hydrophilicity of artery-to-vein shunts and thus to reduce thrombus formation. A highly antithrombogenic polymer was prepared by immobilizing the fibrinolytic enzyme urokinase in a Hydroxyethyl metacrylate (HEMA) hydrogel. Another important aspect of blood compatibility is the power of a biomaterial to activate the complement system. It is a complex system of plasma proteins activated in cascade and involved in the inflammation process. Intraocular lenses made of Hydroxyethyl metacrylate (HEMA) were found ineffective in vifro to activate the serum complement system (C3a, C4a, C5a). Hydroxyethyl metacrylate (HEMA)-grafted polyethylene tubes were not found to inactivate the complement. On the other hand, copolymers of Hydroxyethyl metacrylate (HEMA)/ethyl methacrylate were reported to activate the complement when the polymer contained 60% or more Hydroxyethyl metacrylate (HEMA). Low density lipoprotein adsorption on Hydroxyethyl metacrylate (HEMA) was found to be low due to the hydrophilicity of the resin. Particles of Hydroxyethyl metacrylate (HEMA) were used to study the phagocytic processes of macrophages and neutrophils. The hemocompatibility of Hydroxyethyl metacrylate (HEMA) has led to the development of a medical method used to remove endo or exo toxins from blood. Hemoperfusion takes advantage of activated charcoal to bind such toxics (barbiturates, tricyclic antidepressants). Activated carbon particles have been encapsulated with Hydroxyethyl metacrylate (HEMA) for the construction of hemoperfusion columns; heparinized blood is purified by adsorption of irrelevant toxic molecules onto the entrapped charcoal particles and the cleaned blood is then perfused to the patient. Composites of Hydroxyethyl metacrylate (HEMA), PEG, and activated carbon were found useful for other blood perfusion applications. Another important application of Hydroxyethyl metacrylate (HEMA) is the occlusion of blood vessels in various organs and principally in tumors (which are always hypervascularized). Spherical particles of Hydroxyethyl metacrylate (HEMA) of regular shape were produced by suspension polymerization. When injected in a vessel close to the tumor, the small beads act as emboli and obliterate the smaller vessels. Thus tumor vascularization is stopped and endovascular embolization is followed by tumoral cell necrosis and size reduction of the tumor. The swelling in water of Hydroxyethyl metacrylate (HEMA) beads makes them suitable to close obliteration of vessels. Detailed procedures have been published for preparing such porous Hydroxyethyl metacrylate (HEMA) beads of regular size suitable as artificial thrombi. Optical Lenses The main application of Hydroxyethyl metacrylate (HEMA) hydrogels is the preparation of contact and intraocular lenses used after cataract extraction. Black pigmented Hydroxyethyl metacrylate (HEMA) was used to prepare light-occluding lens after opthalmic surgery. Gentamicin-soaked contact lenses made of a 61.4% Hydroxyethyl metacrylate (HEMA) hydrogel were found to retain bactericidal concentrations of the antibiotic up to 3 days of eye contact. Diffusion of oxygen through hydrophilic contact lens is necessary to avoid corneal oedema. With Hydroxyethyl metacrylate (HEMA) lenses, this is obtained with a 33-pm thickness. Deep corneal stromal opacities were seen in Hydroxyethyl metacrylate (HEMA) contact lenses and were related to chronic corneal anoxia. Deposits are sometimes observed within contact lenses. They occur after 12 months of daily lens wear and may be associated with vision decrement. The protein deposits on contact lenses vary according to the copolymer: With Hydroxyethyl metacrylate (HEMA)Imethacrylic acid copolymers, lenses absorb large amounts of lysosyme, and Hydroxyethyl metacrylate (HEMA) IMMA copolymer preferentially adsorbs albumin. Contact lenses of copolymers of Hydroxyethyl metacrylate (HEMA) with methacrylic acid or various silanes were found to adsorb less lysosyme than unsilanized lenses. Deposits of calcium in contact lens made of Hydroxyethyl metacrylate (HEMA) have been reported. Intraocular strips of Hydroxyethyl metacrylate (HEMA) hydrogels containing small amounts (1.2-1.4%) of methacrylic acid were found to be favorably tolerated in vivo due to the high water and carboxylic group content. Hydroxyethyl metacrylate (HEMA) intraocular lens were found to be better tolerated than conventional amino-polyamide-base implants, but the presence of microvilli on corneal cells suggests the release of impurities from the resin. Hydroxyethyl metacrylate (HEMA)-based intraocular lenses were found to be well preserved after Nd:YAG laser surgery. Various drugs (chloramphenicol, pilocarpine, dexamethasone) were found to have a longer washout period when entrapped in intraocular lenses than in the human lens. The clinicobiological results of Hydroxyethyl metacrylate (HEMA) intraocular lenses were found to be the most favorable, with 92% of implanted patients recovering visual acuity.
HYDROXYETHYL METHACRYLATE (HEMA)
DESCRIPTION:

Hydroxyethyl Methacrylate (HEMA) (also known as glycol methacrylate) is the organic compound with the chemical formula H2C\dC(CH3)CO2CH2CH2OH.
Hydroxyethyl Methacrylate (HEMA) is a colorless viscous liquid that readily polymerizes.
Hydroxyethyl Methacrylate (HEMA) is a monomer that is used to make various polymers.

CAS Number: 868-77-9
EC Number 212-782-2
Molecular Weight: 130.14
Linear Formula: CH2=C(CH3)COOCH2CH2OH


SYNONYM(S) OF HYDROXYETHYL METHACRYLATE (HEMA):
1,2-Ethanediol mono(2-methylpropenoate), Glycol methacrylate, HEMA,HEMA; hydroxyethylmethacrylate; glycol methacrylate; glycol monomethacrylate; hydroxyethyl methacrylate; ethylene glycol methacrylate; 2-(methacryloyloxy)ethanol,2-hydroxyethyl methacrylate,glycol methacrylate,HEMA,Historesin,hydroxyethyl methacrylate,2-HYDROXYETHYL METHACRYLATE,868-77-9,Glycol methacrylate,Hydroxyethyl methacrylate,HEMA,Glycol monomethacrylate,Ethylene glycol methacrylate,2-Hydroxyethylmethacrylate,2-(Methacryloyloxy)ethanol,2-hydroxyethyl 2-methylprop-2-enoate,Mhoromer,Methacrylic acid, 2-hydroxyethyl ester,Monomer MG-1,Ethylene glycol monomethacrylate,(hydroxyethyl)methacrylate,beta-Hydroxyethyl methacrylate,NSC 24180,2-Hydroxyethyl methylacrylate,2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester,PHEMA,CCRIS 6879,CHEBI:34288,Ethylene glycol, monomethacrylate,HSDB 5442,12676-48-1,EINECS 212-782-2,UNII-6E1I4IV47V,BRN 1071583,Monomethacrylic ether of ethylene glycol,6E1I4IV47V,DTXSID7022128,PEG-MA,1,2-Ethanediol mono(2-methyl)-2-propenoate,NSC-24180,2-hydroxyethylmethylacrylate,ethyleneglycol monomethacrylate,DTXCID202128,.beta.-Hydroxyethyl methacrylate,2-hydroxyethylmethacrylate (hema),EC 212-782-2,4-02-00-01530 (Beilstein Handbook Reference),NSC24180,2-Hydroxyethyl methacrylate (HEMA),MFCD00002863,MFCD00081879,2-Hydroxyethyl Methacrylate (stabilized with MEHQ),Bisomer HEMA,2-Hydroxyethyl methacrylate,ophthalmic grade,hydroxyethylmethacrylate,1,2-Ethanediol mono(2-methylpropenoate),hydroxyehtyl methacrylate,hydroxylethyl methacrylate,2-hydroxyetyl methacrylate,2-HEMA,Epitope ID:117123,2-hydroxylethyl methacrylate,2-hydroxyethyl(methacrylate),SCHEMBL14886,WLN: Q2OVY1&U1,2-methacryloyloxyethyl alcohol,BIDD:ER0648,CHEMBL1730239,CHEBI:53709,2-Hydroxyethyl methacrylate, 98%,2-Hydroxyethyl 2-methylacrylate #,Tox21_200415,AKOS015899920,Methacrylic,Acid 2-Hydroxyethyl Ester,CS-W013439,DS-9647,HY-W012723,NCGC00166101-01,NCGC00166101-02,NCGC00257969-01,CAS-868-77-9,PD167321,SY279104,2-HYDROXYETHYL METHACRYLATE [HSDB],2-Hydroxyethyl methacrylate,low acid grade,1,2-Ethanediol, mono(2-methyl)-2-propenyl,2-HYDROXYETHYL METHACRYLATE [WHO-DD],M0085,NS00008941,EN300-98188,D70640,2-Hydroxyethyl methacrylate(hema),technical grade,2-Methyl-2-propenoic acid, 2-hydroxyethyl ester,Hydroxyethyl methacrylate(5.9cp(30 degrees c)),2-Propenoic acid, 2-methyl-,2-hydroxiethyl ester,A904584,Hydroxyethyl methacrylate(>200cp(25 degrees c)),Q424799,2-Hydroxyethyl Methacrylate, (stabilized with MEHQ),J-509674,2-Hydroxyethyl Methacrylate, Stabilized with 250 ppm MEHQ,2-Hydroxyethyl methacrylate, embedding medium (for microscopy),InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H,2-Hydroxyethyl methacrylate, >=99%, contains <=50 ppm monomethyl ether hydroquinone as inhibitor,2-Hydroxyethyl methacrylate, contains <=250 ppm monomethyl ether hydroquinone as inhibitor, 97%


Hydroxyethyl Methacrylate (HEMA), Normal Grade, in the form of a colorless, clear liquid, is an industrial solvent that can be used in automotive coatings and primers.
Because of its vinyl double bond, this product can copolymerize with other monomers to produce copolymers with hydroxy groups.


Hydroxyethyl Methacrylate (HEMA) is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Hydroxyethyl Methacrylate (HEMA) has a role as a polymerisation monomer and an allergen.
Hydroxyethyl Methacrylate (HEMA) is functionally related to an ethylene glycol and a methacrylic acid.


Hydroxyethyl Methacrylate (HEMA) is a hydroxyester compound and a resin monomer used in desensitizing dentin.
By applying 2-hydroxyethyl methacrylate locally to sensitive teeth, sensitive areas in the teeth get sealed and block the dentinal tubules at the dentin surface from stimuli that cause pain.
This prevents excitation of the tooth nerve and relieves pain caused by tooth hypersensitivity.




Hydroxyethyl Methacrylate (HEMA) is an ester of Methacrylic acid and is used as a raw material component in the synthesis of polymers.
Hydroxyethyl Methacrylate (HEMA) forms a homopolymer and copolymers.
Copolymers of Hydroxyethyl Methacrylate (HEMA) can be prepared with (meth)acrylic acid and its salts, amides, and esters, as well as (meth)acrylates, acrylonitrile, maleic acid esters, vinyl acetate, vinyl chloride, vinylidene chloride, styrene, butadiene, and other monomers.

Hydroxyethyl Methacrylate (HEMA), easily entering into the reaction of accession with a wide range of organic and inorganic substances, is used for the synthesis of organic low molecular weight substances.



Clear colorless, easily flowable liquid monomer with a pungent, sweet odor.
Hydroxyethyl Methacrylate (HEMA) comprises of a polymerizable methacrylate functional group in one end and a reactive hydroxyl group at the other end.
Hydroxyethyl Methacrylate (HEMA) easily dissolves in water and has relatively low volatility.

Hydroxyethyl Methacrylate (HEMA) copolymerizes readily with a wide variety of monomers, and the added hydroxyl groups improve adhesion to surfaces, incorporate cross-link sites, and impart corrosion, fogging, and abrasion resistance as well as contribute to low odor, color, and volatility.





SYNTHESIS OF HYDROXYETHYL METHACRYLATE (HEMA):
Hydroxyethylmethacrylate was first synthesized around 1925.
Common methods of synthesis are:[5]
reaction of methacrylic acid with ethylene oxide;
esterification of methacrylic acid with a large excess of ethylene glycol.

Both these methods give also some amount of ethylene glycol dimethacrylate.
During polymerization of hydroxyethylmethacrylate, it works as crosslinking agent.[5]


PROPERTIES OF HYDROXYETHYL METHACRYLATE (HEMA):
Hydroxyethylmethacrylate is completely miscible with water and ethanol, but its polymer is practically insoluble in common solvents.
Its viscosity is 0.0701 Pa⋅s at 20°C[6] and 0.005 Pa⋅s at 30°C.[3]
During polymerization, it shrinks by approximately 6%.[6]


APPLICATIONS OF HYDROXYETHYL METHACRYLATE (HEMA):
Contact lenses[edit]
In 1960, O. Wichterle and D. Lím[7] described its use in synthesis of hydrophilic crosslinked networks, and these results had great importance for manufacture of soft contact lenses.

Polyhydroxyethylmethacrylate is hydrophilic: it is capable of absorbing from 10 to 600% water relative to the dry weight.
Because of this property, it was one of the first materials to be used in the manufacture of soft contact lenses.

Use in 3D printing
Hydroxyethylmethacrylate lends itself well to applications in 3D printing as it cures quickly at room temperature when exposed to UV light in the presence of photoinitiators.
It may be used as a monomeric matrix in which 40nm silica particles are suspended for 3D glass printing.[9]
When combined with a suitable blowing agent such as BOC anhydride it forms a foaming resin which expands when heated.[10]

Other
In electron microscopy, later in light microscopy, hydroxyethylmethacrylate serves as an embedding medium.
When treated with polyisocyanates, polyhydroxyethylmethacrylate makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints.


FEATURES & BENEFITS OF HYDROXYETHYL METHACRYLATE (HEMA)
Chemical resistance
Hydraulic stability
Flexibility
Impact resistance
Adhesion
Weatherability


APPLICATIONS AREAS:
Hydroxyethyl Methacrylate (HEMA) is used in the preparation of solid polymers, acrylic dispersions, and polymer solutions, which are used in various industries.

Hydroxyethyl Methacrylate (HEMA) is applied in the production of:
Coating Resins
Automotive coatings
Architectural coatings
Paper coatings
Industrial coatings
Plastics
Hygiene products
Adhesives & Sealants
Textile finishes
Printing inks
Contact lens
Modifiers
Photosensitive materials
Additives for oil production and transportation








CHEMICAL AND PHYSICAL PROPERTIES OF HYDROXYETHYL METHACRYLATE (HEMA):
Chemical formula C6H10O3
Molar mass 130.143 g•mol−1
Appearance Colourless liquid
Density 1.07 g/cm3
Melting point −99 °C (−146 °F; 174 K)[2]
Boiling point 213 °C (415 °F; 486 K)[2]
Solubility in water miscible
log P 0.50[1]
Vapor pressure 0.08 hPa
Molecular Weight
130.14 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3
0.5
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
130.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
130.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
46.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
9
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
118
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
CAS number 868-77-9
EC index number 607-124-00-X
EC number 212-782-2
Hill Formula C₆H₁₀O₃
Chemical formula CH₂=C(CH₃)COOCH₂CH₂OH
Molar Mass 130.14 g/mol
HS Code 2916 14 00
Assay (GC, area%) ≥ 97.0 % (a/a)
Density (d 20 °C/ 4 °C) 1.069 - 1.072
Identity (IR) passes test
Molecular Weight 130
Appearance Colorless transparent liquid
Odor Aromatic odor
Refractive Index (25℃) 1.451
Boiling Point (℃ 760mmHg) 205
Freezing Point (℃ 760mmHg) -12
Flash Point (℃) 107 (Cleveland open-cup flash test)
Viscosity (CP 25℃) 6.1
Solubility Readily soluble in water
Stability&
Reactivity Polymerize under sunlight and heat
Chemical Properties:
Purity
min. 98.0 %
Acid Value
max. 1.0 %
Water content
max. 0.3 %
Color APHA
max. 30
Physical Properties:
Appearance
colorless
Physical form
Liquid
Odor
Aromatic
Molecular weight
130.14 g/mol
Polymer Tg
Tg 25 °C
Tg
- 6 °C
Density
1.073 g/mL at 25°C
Boiling Point
211 °C
Freezing Point
- 12 °C
Flash point
96 °C
Melting Point
- 60 °C
Viscosity
6.8 (mPa.s) at 20 °C
Vapor Point
0.065 hPa
pH
4 (500 g/l in water)
Alternative names:
1,2-Ethanediol mono(2-methylpropenoate); Glycol methacrylate; HEMA
Application:
2-Hydroxyethyl methacrylate is wide applications for drug delivery
CAS number :
868-77-9
Purity :
97%
Molecular weight :
130.14
Molecular Formula :
C 6 H 10 O 3


SAFETY INFORMATION ABOUT HYDROXYETHYL METHACRYLATE (HEMA):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



HYDROXYETHYL UREA ( (2-hydroxyethyl)urea )
HYDROXYETHYL-2-NITRO-P-TOLUIDINE N° CAS : 100418-33-5 Nom INCI : HYDROXYETHYL-2-NITRO-P-TOLUIDINE Nom chimique : 1-Methyl-3-nitro-4-(.beta.-hydroxyethyl)aminobenzene N° EINECS/ELINCS : 408-090-7
HYDROXYETHYL-2-NITRO-P-TOLUIDINE
HYDROXYETHYLCELLULOSE,Tylose, N° CAS : 9004-62-0, Nom INCI : HYDROXYETHYLCELLULOSE, Classification : Composé éthoxylé, L'hydroxyéthylcellulose est un polymère obtenu par l'action d'oxyde d'éthylène sur de la cellulose. Il est utilisé en cosmétique en tant qu'épaississant.Ses fonctions (INCI). Agent fixant : Permet la cohésion de différents ingrédients cosmétiques Stabilisateur d'émulsion : Favorise le processus d'émulsification et améliore la stabilité et la durée de conservation de l'émulsion. Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Agent stabilisant : Améliore les ingrédients ou la stabilité de la formulation et la durée de conservation. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Noms français : Cellulose, hydroyéthyl de; Hydroxy-2 éthyl cellulose. Noms anglais : 2-Hydroxyethyl cellulose; 2-HYDROXYETHYL CELLULOSE ETHER; CELLULOSE HYDROXYETHYL ETHER; CELLULOSE HYDROXYETHYLATE; CELLULOSE, 2-HYDROXYETHYL ETHER; CELLULOSE, ETHYLENE OXIDE-GRAFTED;HYDROXY ETHYL CELLULOSE HYDROXYETHYL CELLULOSE; HYDROXYETHYL CELLULOSE ETHER; HYDROXYETHYL ETHER CELLULOSE; HYDROXYETHYLCELLULOSE; OXIRANE, POLYMER WITH CELLULOSE Utilisation : Agent épaississant, fabrication de produits pharmaceutiques
HYDROXYETHYLCELLULOSE ( Cellulose, hydroyéthyl de )
N-(2-Hydroxyethyl)ethylenediamine-N,N′,N′-triacetic acid; N-Carboxymethyl-N′-(2-hydroxyethyl)-N,N′-ethylenediglycine, HEDTA, HEEDTA cas no: 150-39-0
HYDROXYETHYLETHYLENEDIAMINTRIACETIC ACID
Cellulose,2-hydroxyethylmethylether;'Tylose'® MH 300;Hydroxythyl Methyl Cellulose;HydroxythylMethylCellulose(Hemc);HEMC;HYDROETHYLMETHYL CELLULOSE (HEMC);METHYL HYDROXYETHYL CELLULOSE (20-40CPS: 2% IN WATER);Methyl Hydroxyethyl Cellulose (20-40mPa.s, 2% in Water at 20deg C) CAS NO:9032-42-2
HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE)
Hydroxyethylmethacrylate (glycol methacrylate) (also known as glycol methacrylate) is the organic compound with the chemical formula H2C\dC(CH3)CO2CH2CH2OH.
Hydroxyethylmethacrylate (glycol methacrylate) is a colorless viscous liquid that readily polymerized.


CAS Number: 868-77-9
EC Number: 212-782-2
Chemical formula: C6H10O3



SYNONYMS:
2-Hydroxyethyl 2-methylprop-2-enoate, 2-Methyl-2-propenoic Acid 2-Hydroxyethyl Ester, 2-(Methacryloyloxy)ethanol, Acryester HISS, Acryester HO, Bisomer HEMA, Bisomer SR, Blemmer E, EB 109, Ethylene Glycol Methacrylate, Ethylene Glycol Monomethacrylate, GE 610, Glycol Methacrylate, Glycol Monomethacrylate, HEMA, HEMA 90, Light Ester HO, Light Ester HO 250, Mhoromer BM 903, Mhoromer BM 905, Monomer MG 1, NSC 24180, Rocryl 400, β-Hydroxyethyl Methacrylate, 2-Propenoic acid,2-methyl-,2-hydroxyethyl ester, Methacrylic acid,2-hydroxyethyl ester, Methacrylic acid,ester with glycol, Glycol methacrylate, Glycol monomethacrylate, Monomer MG 1, β-Hydroxyethyl methacrylate, 2-Hydroxyethyl methacrylate, Ethylene glycol monomethacrylate, 2-(Methacryloyloxy)ethanol, Ethylene glycol methacrylate, Acryester HO, Rocryl 400, Light Ester HO, Bisomer SR, Mhoromer BM 903, NSC 24180, Blemmer E, Acryester HISS, Mhoromer BM 905, GE 610, HEMA, Light Ester HO 250, Bisomer HEMA, HEMA 90, EB 109 (monomer), EB 109, 2-HEMA, Kayarad 2-HEMA, Acryester HOMA, Light Ester HO 250M, EM 321, 2-Hydroxyethyl 2-methylprop-2-enoate, Acryl Ester HO, Light Ester HO 250N, Visiomer HEMA 98, M 0085, JB 4 Plus, Visiomer HEMA 97, H 140643, 51026-91-6, 58308-22-8, 60974-06-3, 61497-49-2, 112813-65-7, 123991-13-9, 132051-71-9, 141668-69-1, 151638-45-8, 155280-45-8, 173306-28-0, 201463-85-6, 203300-24-7, 203497-53-4, 211862-46-3, 212555-08-3, 219840-96-7, 225107-31-3, 282528-79-4, 473256-73-4, 1136534-55-8, 1151978-80-1, 1184921-46-7, 1206159-39-8, 1260379-87-0, 1418001-98-5, 1449201-78-8, 2231343-05-6, 2242757-54-4, .beta.-Hydroxyethyl methacrylate, 1,2-Ethanediol mono(2-methyl)-2-propenoate, 1,2-Ethanediol mono(2-methylpropenoate), 2-(Methacryloyloxy)ethanol, 2-Hydroxyethyl 2-methylacrylate, 2-Hydroxyethyl methacrylate (HEMA), 2-Hydroxyethylmethacrylate, 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer, 2-hydroxyethyl 2-methylprop-2-enoate, AC1L21KL, Ethylene glycol methacrylate, Ethylene glycol monomethacrylate, Ethylene glycol, monomethacrylate, Glycol methacrylate, Glycol methacrylate gel, Glycol monomethacrylate, HEMA, Hydroxyethyl methacrylate, Hydroxymethacrylate gel, I14-11804, Methacrylic Acid 2-Hydroxyethyl Ester, Methacrylic acid, 2-hydroxyethyl ester, Methacrylic acid, polyethylene glycol monoester, Mhoromer, Monomer MG-1, Monomethacrylic ether of ethylene glycol, PEG-MA, PHEMA, POLYHYDROXYETHYL METHACRYLATE, Poly(2-HEMA), Poly(2-hydroxyethyl methacrylate), Poly(hydroxyethyl methacrylate), Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propen-1-yl)-omega-hydroxy-, Poly(oxy-1,2-ethanediyl), alpha-(2-methyl-1-oxo-2-propenyl)-omega-hydroxy-, Poly-hema, Polyglycol methacrylate, alpha-methacryloyl-omega-hydroxypoly(oxyethylene), beta-Hydroxyethyl methacrylate, poly(ethylene glycol methacrylate), poly(ethylene glycol) methacrylate, polyethylene glycol methacrylate, HEMA, GMA, HYDROXYETHYL METHACRYLATE, GLYCOL METHACRYLATE, ETHYLENE GLYCOL METHACRYLATE, BisoMer HEMA, N5-Methyl-L-glutamine, Hydroxyethyl Methacrylat, 2-(Methacryloyloxy)ethanol, Hydroxyethyl methacrylate (HEMA), HEMA, Hydroxyethylmethacrylate, Glycol methacrylate, Glycol monomethacrylate, Hydroxyethyl methacrylate, Ethylene glycol methacrylate, 2-(Methacryloyloxy)ethanol, HEMA, hydroxyethylmethacrylate, glycol methacrylate, glycol monomethacrylate, hydroxyethyl methacrylate, ethylene glycol methacrylate, 2-(methacryloyloxy)ethanol, 2-hydroxyethyl methacrylate, 2-hydroxyethyl-2-methyl-2-propenoate, 2-hydroxyethyl-2-methylpropenoate, 2-methyl-2-propenoic acid 2-hydroxyethyl ester, 2-propenoic acid, 2-methyl-, 2-hydroxyethyl ester, beta-hydroxyethylmethacrylate, BISOMER HEMA, ethylene glycol methacrylate, ethylene glycol monomethacrylate, ethylene glycol, monomethacrylate, glycol methacrylate, glycol monomethacrylate, HEMA, hydroxyethyl methacrylate, metacrylic acid, 2-hydroxyethyl ester, methacrylic acid 2-hydroxyethyl ester, methylpropenoic acid, hydroxyethyl ester, mhoromer, monomer MG-1, monomethacrylic ether of ethylene glycol, 1,2-Ethanediol, mono(2-methyl)-2-propenoate, 1,2-Ethanediol, mono(2-methyl)-2-propenyl, 2-(Methacryloyloxy)ethanol, 2-Methyl-2-propenoic acid, 2-hydroxyethyl ester, 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, 2-hydroxypropyl acrylate, Bisomer HEMA, Ethylene glycol methacrylate, Ethylene glycol monomethacrylate, GMA, Glycol methacrylate, Glycol monomethacrylate, HEMA, Hydroxyethyl methacrylate, Methacrylic acid, 2-hydroxyethyl ester, Mhoromer, Monomer MG-1, NSC 24180, «beta»-Hydroxyethyl methacrylate, «beta»-Hydroxyethyl methacrylate, 2-HYDROXYETHYL METHACRYLATE, 868-77-9, Glycol methacrylate, Hydroxyethyl methacrylate, HEMA, Glycol monomethacrylate, Ethylene glycol methacrylate, 2-Hydroxyethylmethacrylate, 2-(Methacryloyloxy)ethanol, 2-hydroxyethyl 2-methylprop-2-enoate, Mhoromer, Methacrylic acid, 2-hydroxyethyl ester, Monomer MG-1, Ethylene glycol monomethacrylate, (hydroxyethyl)methacrylate, beta-Hydroxyethyl methacrylate, NSC 24180, 2-Hydroxyethyl 2-methylacrylate, 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, PHEMA, CCRIS 6879, CHEBI:34288, Ethylene glycol, monomethacrylate, HSDB 5442, 12676-48-1, EINECS 212-782-2, UNII-6E1I4IV47V, BRN 1071583, Monomethacrylic ether of ethylene glycol, 6E1I4IV47V, DTXSID7022128, PEG-MA, 1,2-Ethanediol mono(2-methyl)-2-propenoate, NSC-24180, 2-hydroxyethylmethylacrylate, ethyleneglycol monomethacrylate, DTXCID202128, .beta.-Hydroxyethyl methacrylate, 2-hydroxyethylmethacrylate (hema), EC 212-782-2, 4-02-00-01530 (Beilstein Handbook Reference), NSC24180, 2-Hydroxyethyl methacrylate (HEMA), MFCD00002863, MFCD00081879, 2-Hydroxyethyl Methacrylate (stabilized with MEHQ), Bisomer HEMA, 2-Hydroxyethyl methacrylate, ophthalmic grade, hydroxyethylmethacrylate, 1,2-Ethanediol mono(2-methylpropenoate), hydroxyehtyl methacrylate, hydroxylethyl methacrylate, HEMA [INCI], 2-hydroxyetyl methacrylate, 2-HEMA, Epitope ID:117123, 2-Hydroxyethyl methacrylate, 2-hydroxyethyl(methacrylate), SCHEMBL14886, WLN: Q2OVY1&U1, 2-methacryloyloxyethyl alcohol, BIDD:ER0648, CHEMBL1730239, CHEBI:53709, 2-Hydroxyethyl methacrylate, 98%, 2-Hydroxyethyl 2-methylacrylate #, Tox21_200415, AKOS015899920, Methacrylic Acid 2-Hydroxyethyl Ester, CS-W013439, DS-9647, HY-W012723, NCGC00166101-01, NCGC00166101-02, NCGC00257969-01, CAS-868-77-9, PD167321, SY279104, 2-HYDROXYETHYL METHACRYLATE [HSDB], 2-Hydroxyethyl methacrylate, low acid grade, 1,2-Ethanediol, mono(2-methyl)-2-propenyl, 2-HYDROXYETHYL METHACRYLATE [WHO-DD], M0085, NS00008941, EN300-98188, D70640, 2-Hydroxyethyl methacrylate(hema), technical grade, 2-Methyl-2-propenoic acid, 2-hydroxyethyl ester, Hydroxyethyl methacrylate(5.9cp(30 degrees c)), 2-Propenoic acid, 2-methyl-,2-hydroxiethyl ester, A904584, Hydroxyethyl methacrylate(>200cp(25 degrees c)), Q424799, 2-Hydroxyethyl Methacrylate, (stabilized with MEHQ), J-509674, 2-Hydroxyethyl Methacrylate, Stabilized with 250 ppm MEHQ, 2-Hydroxyethyl methacrylate, embedding medium (for microscopy), InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H, 2-Hydroxyethyl methacrylate, >=99%, contains <=50 ppm monomethyl ether hydroquinone as inhibitor, 2-Hydroxyethyl methacrylate, contains <=250 ppm monomethyl ether hydroquinone as inhibitor, 97%, (Hydroxyethyl)methacrylate, 1,2-Ethanediol mono(2-methylpropenoate), 212-782-2 [EINECS], 2-Hydroxyethyl methacrylate, 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester [ACD/Index Name], 868-77-9 [RN], Ethylene glycol methacrylate, Glycol methacrylate, Glycol monomethacrylate, HEMA, hydroxyethyl methacrylate, MFCD00002863 [MDL number], β-Hydroxyethyl methacrylate, [868-77-9], 1,2-Ethanediol mono(2-methyl)-2-propenoate, 1,2-Ethanediol, mono(2-methyl)-2-propenyl, 103285-00-3 [RN], 10526753, 112813-65-7 [RN], 118601-61-9 [RN], 123991-13-9 [RN], 12676-48-1 [RN], 129997-87-1 [RN], 133184-08-4 [RN], 141668-69-1 [RN], 152824-98-1 [RN], 156932-46-6 [RN], 162774-76-7 [RN], 164916-20-5 [RN], 173306-28-0 [RN], 181319-32-4 [RN], 191219-71-3 [RN], 2-(Methacryloyloxy)ethanol, 201463-85-6 [RN], 203300-24-7 [RN], 203497-53-4 [RN], 212555-08-3 [RN], 225107-31-3 [RN], 25249-16-5 [RN], 25736-86-1 [RN], 2-HYDROXY ETHYL METHACRYLATE, 2-Hydroxyethyl 2-methylacrylate, 2-hydroxyethyl 2-methylprop-2-enoate, 2-Hydroxyethyl methacrylate (stabilised with hydroquinone monomethyl ether), 2-hydroxyethyl methacrylate 97%, 2-hydroxyethyl methacrylate, 97%, stabilized, 2-Hydroxyethyl methacrylate|2-(Methacryloyloxy)ethanol, 2-hydroxyethylmethacrylate, 2-Methyl-2-propenoic acid 2-hydroxyethyl ester, 2-Methyl-2-propenoic acid, 2-hydroxyethyl ester, 2-methylacrylic acid 2-hydroxyethyl ester, 2-methylprop-2-enoic acid 2-hydroxyethyl ester, 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, homopolymer, 4-02-00-01530 [Beilstein], 4-02-00-01530 (Beilstein Handbook Reference) [Beilstein], 51026-91-6 [RN], 58308-22-8 [RN], 60974-06-3 [RN], 61497-49-2 [RN], 82601-55-6 [RN], 97429-31-7 [RN], 98%, stabilized with MEHQ, Acryester HISS, Bisomer HEMA, EINECS 212-782-2, ethane-1,2-diol, 2-methyl-2-propenoic acid, ETHYLENE GLYCOL MONOMETHACRYLATE, Ethylene glycol, monomethacrylate, GMA, β-hydroxyethyl methacrylate, InChI=1/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H, Methacrylic acid 2-hydroxyethyl ester, Methacrylic acid, 2-hydroxyethyl ester, Monomer MG-1, NCGC00166101-01, WLN : Q2OVY1&U1, β-Hydroxyethyl methacrylate



Hydroxyethylmethacrylate (glycol methacrylate) is perhaps the most widely studied and used neutral hydrophilic monomer.
Hydroxyethylmethacrylate (glycol methacrylate) is soluble, its homopolymer is water-insoluble but plasticized and swollen in water.
Hydroxyethylmethacrylate (glycol methacrylate) is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbants for body fluids and lubricious coatings.


Hydroxyethylmethacrylate (glycol methacrylate) is perhaps the most widely studied and used neutral hydrophilic monomer.
Hydroxyethylmethacrylate (glycol methacrylate) is soluble, its homopolymer is water-insoluble but plasticized and swollen in water.
Hydroxyethylmethacrylate (glycol methacrylate) is a clear, colourless liquid with a sweet odour which is soluble in water.


Hydroxyethylmethacrylate (glycol methacrylate) is an ester of methacrylic acid used to make the polymer polyhydroxyethyl methacrylate, which was one of the first materials to be used successfully in flexible contact lenses.
Hydroxyethylmethacrylate (glycol methacrylate) copolymerizes readily with a wide range of monomers, and the added hydroxyl groups provide improved adhesion to surfaces, hydrophilicity, resistance to corrosion, fogging, and abrasion, incorporate cross-link sites, and reduce odour, colour, and volatility.


Hydroxyethylmethacrylate (glycol methacrylate) is the monomer that is used to make the polymer polyhydroxyethylmethacrylate.
Hydroxyethylmethacrylate (glycol methacrylate) is hydrophobic; however, when the polymer is subjected to water it will swell due to the molecule's hydrophilic pendant group.


Hydroxyethylmethacrylate (glycol methacrylate) (also known as glycol methacrylate) is the organic compound with the chemical formula H2C\dC(CH3)CO2CH2CH2OH.
Hydroxyethylmethacrylate (glycol methacrylate) is a colorless viscous liquid that readily polymerizes.
Hydroxyethylmethacrylate (glycol methacrylate) is a monomer that is used to make various polymers.


Hydroxyethylmethacrylate (glycol methacrylate) is a neutral hydrophilic monomer useful in UV curing polymer systems & durable high gloss coatings.
Other industrial applications of Hydroxyethylmethacrylate (glycol methacrylate) include nails, dental, hydrogels (such as contact lens), UV inks & adhesives.


Hydroxyethylmethacrylate (glycol methacrylate) provides scratch, solvent & weather resistance, control of hydrophobicity &/or can introduce reactive sites.
Hydroxyethylmethacrylate (glycol methacrylate) is perhaps the most widely studied and used neutral hydrophilic monomer.


Hydroxyethylmethacrylate (glycol methacrylate) (also known as glycol methacrylate) is the organic compound with the chemical formula H2C\dC(CH3)CO2CH2CH2OH.
Hydroxyethylmethacrylate (glycol methacrylate) is a colorless viscous liquid that readily polymerized.
Hydroxyethylmethacrylate (glycol methacrylate) is a monomer that is used to make various polymers.


Hydroxyethylmethacrylate (glycol methacrylate) is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Hydroxyethylmethacrylate (glycol methacrylate) has a role as a polymerisation monomer and an allergen.
Hydroxyethylmethacrylate (glycol methacrylate) derives from an ethylene glycol and a methacrylic acid.


Hydroxyethylmethacrylate (glycol methacrylate) is a hydroxyester compound and a resin monomer used in desensitizing dentin.
By applying Hydroxyethylmethacrylate (glycol methacrylate) locally to sensitive teeth, sensitive areas in the teeth get sealed and block the dentinal tubules at the dentin surface from stimuli that cause pain.


This bifunctional monomer, Hydroxyethylmethacrylate (glycol methacrylate), which contains both acrylate and hydroxyl functionality, is produced from the esterification of methacrylic acid by ethylene glycol or from ethylene oxide via a ring-opening process.
Hydroxyethylmethacrylate (glycol methacrylate) is an ester of methacrylic acid, soluble in water and has relatively low volatility.


Hydroxyethylmethacrylate (glycol methacrylate) copolymerizes easily with a variety of monomers, incorporates cross-link sites, imparts corrosion, fogging and abrasion resistance, and the hydroxyl group improves adhesion.
Hydroxyethylmethacrylate (glycol methacrylate) is also a key raw material for acrylic polyols.


Hydroxyethylmethacrylate (glycol methacrylate)'s copolymers can be prepared with (meth)acrylic acid and its salts, amides, and esters, as well as with (meth)acrylates, acrylonitrile, maleic acid esters, vinyl acetate, vinyl chloride, vinylidene chloride, styrene, butadiene, and other monomers.


This prevents excitation of the tooth nerve and relieves pain caused by tooth hypersensitivity.
Hydroxyethylmethacrylate (glycol methacrylate), also known as ethylene glycol methacrylate or HEMA, belongs to the class of organic compounds known as enoate esters.


These are an alpha,beta-unsaturated carboxylic ester of general formula R1C(R2)=C(R3)C(=O)OR4 (R4= organyl compound) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position.
Based on a literature review a significant number of articles have been published on Hydroxyethylmethacrylate (glycol methacrylate).


Hydroxyethylmethacrylate (glycol methacrylate) is the monomer that is used to make the polymer polyhydroxyethylmethacrylate.
Hydroxyethylmethacrylate (glycol methacrylate) is hydrophobic; however, when the polymer is subjected to water it will swell due to the molecule’s hydrophilic pendant group.


Hydroxyethylmethacrylate (glycol methacrylate) is a clear, colourless liquid with a characteristic odour.
Hydroxyethylmethacrylate (glycol methacrylate) is an ester of methacrylic acid.
Hydroxyethylmethacrylate (glycol methacrylate) easily dissolves in water, relatively low volatility, non-toxic and non-yellowing.


Hydroxyethylmethacrylate (glycol methacrylate) copolymerizes readily with a wide variety of monomers, and the added hydroxyl groups improve adhesion to surfaces, incorporate cross-linking sites, and impart corrosion, fogging, and abrasion resistance, as well as contribute to low odour, colour, and volatility.
The Hydroxyethylmethacrylate (glycol methacrylate) is water soluble, while its homopolymer is water-insoluble but plasticized and swollen in water.


Hydroxyethylmethacrylate (glycol methacrylate) has been identified in human blood as reported by (PMID: 31557052 ).
Hydroxyethylmethacrylate (glycol methacrylate) is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives.


Hydroxyethylmethacrylate (glycol methacrylate) is an enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Technically Hydroxyethylmethacrylate (glycol methacrylate) is part of the human exposome.


Hydroxyethylmethacrylate (glycol methacrylate) is the monomer that is used to make the polymer polyhydroxyethylmethacrylate.
Hydroxyethylmethacrylate (glycol methacrylate) is hydrophobic; however, when the polymer is subjected to water it will swell due to the molecule's hydrophilic pendant group.



USES and APPLICATIONS of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) is the methacrylic monomer for use in UV inks, adhesives, lacquers, dental materials, artificial nails, etc.
In electron microscopy, later in light microscopy, Hydroxyethylmethacrylate (glycol methacrylate) serves as an embedding medium.
When treated with polyisocyanates, Hydroxyethylmethacrylate (glycol methacrylate) makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints.


In biomedical applications, Hydroxyethylmethacrylate (glycol methacrylate) is the basis for many hydrogel products such as soft contact lenses, polymer binders for controlled drug release, absorbents for body fluids, and for lubricious coatings.
The Hydroxyethylmethacrylate (glycol methacrylate) is used in certain contact lenses where it has the additional advantage of being rigid and easy to shape with grinding tools when it is dry and then becomes flexible when it absorbs water.


Hydroxyethylmethacrylate (glycol methacrylate) is used in the manufacture of acrylic polymers for adhesives, printing inks, coatings and metal applications.
Hydroxyethylmethacrylate (glycol methacrylate) is also widely used as reactive diluent and alternative to styrene in unsatured polyester (UPR).
Depending on the physical and chemical structure of Hydroxyethylmethacrylate (glycol methacrylate), it is capable of absorbing from 10 to 600% water relative to the dry weight.


Hydroxyethylmethacrylate (glycol methacrylate) is useful as an embedding medium for light microscopy studies.
Hydroxyethylmethacrylate (glycol methacrylate) is useful as an embedding medium for light microscopy studies.
Hydroxyethylmethacrylate (glycol methacrylate) is water-soluble and polymerises at room temperature.


Hydroxyethylmethacrylate (glycol methacrylate) is used as a macromonomer for the synthesis of 2-hydroxyethylmethacrylate-poly(ε-caprolactone) (HEMA-PCL) by coordinated anionic ring opening polymerization (ROP).
Hydroxyethylmethacrylate (glycol methacrylate) is used in UV-curable inks and coatings.


Because of this property, Hydroxyethylmethacrylate (glycol methacrylate) was one of the first materials to be successfully used in the manufacture of flexible contact lenses.
Hydroxyethylmethacrylate (glycol methacrylate) is mainly used for hot curing acrylic coating, UV-curable acrylic materials, photosensitive coating, water soluble plating coating, adhesive, textile treatment agent, ester polymer, modifier polymer, and stem acid water reducing agent, etc.


Hydroxyethylmethacrylate (glycol methacrylate) is used in the manufacture of paint, car paint and primer with resin, polymer resin can be applied to the light, playing board, printing ink, gel (contact lenses) and tinned material coating, transmission electron microscope (TEM) and optical microscope (LM) embedding reagent, samples used for "sensitive antigen sites" of hydration.


Hydroxyethylmethacrylate (glycol methacrylate) is mainly used for resin and coating modification.
Plastic industry, Hydroxyethylmethacrylate (glycol methacrylate) is used in the manufacture of containing active hydroxyl acrylic resin.
Hydroxyethylmethacrylate (glycol methacrylate) is also used in adhesives, artificial nails, dental materials and lacquers.


In dentistry, Hydroxyethylmethacrylate (glycol methacrylate) is one of the main volatile acrylates along with methyl methacrylate.
Further, Hydroxyethylmethacrylate (glycol methacrylate) is used as a monomer in the synthesis of polymers for dental prosthetics and for geotechnical grouting in construction work.


Hydroxyethylmethacrylate (glycol methacrylate) is an ester of Methacrylic Acid and is used as a raw material in the synthesis of polymers.
Hydroxyethylmethacrylate (glycol methacrylate) can form homopolymers and copolymers.
2-Hydroxyethyl Methacrylate (2-HEMA) is used in the preparation of solid polymers, acrylic dispersions, and polymer solutions used in various industries.


Hydroxyethylmethacrylate (glycol methacrylate) is often used to increase the hydrophobicity or surface adhesion of polymers and polymer-based materials such as specialty coatings, resins, adhesives, printing inks, and acrylic plastics.
As a co-monomer with other acrylic ester monomers, Hydroxyethylmethacrylate (glycol methacrylate) can be used to control hydrophobicity or introduce reactive sites.


Hydroxyethylmethacrylate (glycol methacrylate) is used in UV-curable inks and coatings.
Hydroxyethylmethacrylate (glycol methacrylate) is also used in adhesives, artificial nails, dental materials and lacquers.
In dentistry, Hydroxyethylmethacrylate (glycol methacrylate) is one of the main volatile acrylates along with methyl methacrylate.


Main Applications of Hydroxyethylmethacrylate (glycol methacrylate): Coating compounds, photosensitive resins, contact lens.
Application of Hydroxyethylmethacrylate (glycol methacrylate): Adhesives, Adhesives-PSA, Automotive coatings, Coatings for Plastics, Emulsion Polymers, Metal Coatings, Radiation Cure, and Resins.


Hydroxyethylmethacrylate (glycol methacrylate) is a monomer used in the synthesis of various polymers, and the polymer PHEMA of 2-Hydroxyethyl methacrylate is widely used in the synthesis of dental composite materials.
Hydroxyethylmethacrylate (glycol methacrylate) is a well-known biocompatible product of high interest for medical applications in dentistry, bone cements, and biomaterials.


Further, Hydroxyethylmethacrylate (glycol methacrylate) is used as a monomer in the synthesis of polymers for dental prosthetics and for geotechnical grouting in construction work.
Hydroxyethylmethacrylate (glycol methacrylate) is mainly used in producing thermosetting coating, fiber treating agent, adhesive, light-sensitive resin and medical polymer material, etc.


Hydroxyethylmethacrylate (glycol methacrylate) is used in the manufacture of acrylic polymers which in turn are used in a range of commercial applications such as adhesives, paint resins, performance products, reactive systems, printing inks, coatings for automotive, appliance, and metal applications and as an intermediate for chemical syntheses.


Hydroxyethylmethacrylate (glycol methacrylate) is the basis for many hydrogel products such as soft contact lenses, as well as polymer binders for controlled drug release, absorbents for body fluids and lubricious coatings.
As a co-monomer with other ester monomers, Hydroxyethylmethacrylate (glycol methacrylate) can be used to control hydrophobicity or introduce reactive sites.


Hydroxyethylmethacrylate (glycol methacrylate) has a role as a polymerisation monomer and an allergen.
Hydroxyethylmethacrylate (glycol methacrylate) is functionally related to an ethylene glycol and a methacrylic acid.
Hydroxyethylmethacrylate (glycol methacrylate) is a hydroxyester compound and a resin monomer used in desensitizing dentin.


By applying Hydroxyethylmethacrylate (glycol methacrylate) locally to sensitive teeth, sensitive areas in the teeth get sealed and block the dentinal tubules at the dentin surface from stimuli that cause pain.
This prevents excitation of the tooth nerve and relieves pain caused by tooth hypersensitivity.


Hydroxyethylmethacrylate (glycol methacrylate), Stabilized with 250 ppm MEHQ, also known as Hydroxyethyl methacrylate or HEMA, is used to make the polymer polyhydroxyethylmethacrylate which forms a hydrogel in water.
Hydroxyethylmethacrylate (glycol methacrylate) is used adhesives & Sealants, Inks & Digital Inks, Plastic, Resin & Rubber, Polyurethane coatings, UV Monomers, Coatings, Paints, Polymers, Resins.


Hydroxyethylmethacrylate (glycol methacrylate), also known as HEMA, was the first monomer to be used to synthesize hydrogels for biomedical applications.
The water swelling properties of Hydroxyethylmethacrylate (glycol methacrylate) are enhanced by copolymerization with more hydrophilic monomers.
Hydroxyethylmethacrylate (glycol methacrylate) is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) copolymers.


Also, Hydroxyethylmethacrylate (glycol methacrylate) is used to prepare light responsive membranes of PHEMA, HEMA/ acrylamide based specific drug release hydrogel, and water soluble HEMA/methacrylic acid hydrogel for drug delivery.
Effects of Hydroxyethylmethacrylate (glycol methacrylate) on the migration of dental pulp stem cells (in vitro) may be studied.


-Contact lenses uses of Hydroxyethylmethacrylate (glycol methacrylate):
In 1960, O. Wichterle and D. Lím described Hydroxyethylmethacrylate (glycol methacrylate)'s use in synthesis of hydrophilic crosslinked networks, and these results had great importance for manufacture of soft contact lenses.

Hydroxyethylmethacrylate (glycol methacrylate) is hydrophilic: it is capable of absorbing from 10 to 600% water relative to the dry weight.
Because of this property, Hydroxyethylmethacrylate (glycol methacrylate) was one of the first materials to be used in the manufacture of soft contact lenses.


-Use of Hydroxyethylmethacrylate (glycol methacrylate) in 3D printing:
Hydroxyethylmethacrylate (glycol methacrylate) lends itself well to applications in 3D printing as it cures quickly at room temperature when exposed to UV light in the presence of photoinitiators.

Hydroxyethylmethacrylate (glycol methacrylate) may be used as a monomeric matrix in which 40nm silica particles are suspended for 3D glass printing.
When combined with a suitable blowing agent such as BOC anhydride Hydroxyethylmethacrylate (glycol methacrylate) forms a foaming resin which expands when heated.


-Optical lenses uses of Hydroxyethylmethacrylate (glycol methacrylate):
The main application of Hydroxyethylmethacrylate (glycol methacrylate) hydrogels is the preparation of contact and intraocular lenses used after cataract extraction.
Also, the vision decrement associated with deposit accumulation on Hydroxyethylmethacrylate (glycol methacrylate) contact lenses was assessed.


-Dentistry uses of Hydroxyethylmethacrylate (glycol methacrylate):
Hydroxyethylmethacrylate (glycol methacrylate) was found to be highly biocompatible and resorbable for primary teeth endodontic filling.
However, due to its hydrophilicity, Hydroxyethylmethacrylate (glycol methacrylate) appeared more useful in dentistry as a bonding reagent between dentine and other types of restorative resions.


-Contact lenses uses of Hydroxyethylmethacrylate (glycol methacrylate):
In 1960, O. Wichterle and D. Lím described its use in synthesis of hydrophilic crosslinked networks, and these results had great importance for manufacture of soft contact lenses.
Hydroxyethylmethacrylate (glycol methacrylate) is hydrophilic: it is capable of absorbing from 10 to 600% water relative to the dry weight.
Because of this property, Hydroxyethylmethacrylate (glycol methacrylate) was one of the first materials to be used in the manufacture of soft contact lenses.


-Use of Hydroxyethylmethacrylate (glycol methacrylate) in 3D printing:
Hydroxyethylmethacrylate (glycol methacrylate) lends itself well to applications in 3D printing as it cures quickly at room temperature when exposed to UV light in the presence of photoinitiators.
Hydroxyethylmethacrylate (glycol methacrylate) may be used as a monomeric matrix in which 40nm silica particles are suspended for 3D glass printing.
When combined with a suitable blowing agent such as BOC anhydride Hydroxyethylmethacrylate (glycol methacrylate) forms a foaming resin which expands when heated.


-Other use of Hydroxyethylmethacrylate (glycol methacrylate):
In electron microscopy, later in light microscopy, Hydroxyethylmethacrylate (glycol methacrylate) serves as an embedding medium.
When treated with polyisocyanates, Hydroxyethylmethacrylate (glycol methacrylate) makes a crosslinked polymer, an acrylic resin, that is a useful component in some paints.



PROPERTIES OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) is a colorless transparent liquid, boiling point 95ºC (1333.22Pa), soluble in water, alcohol, ether, ester and other solvents



SYNTHESIS OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) was first synthesized around 1925.
Common methods of synthesis are:
reaction of methacrylic acid with ethylene oxide;
esterification of methacrylic acid with a large excess of ethylene glycol.
Both these methods give also some amount of ethylene glycol dimethacrylate.
During polymerization of Hydroxyethylmethacrylate (glycol methacrylate), it works as crosslinking agent.



PROPERTIES OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) is completely miscible with water and ethanol, but its polymer is practically insoluble in common solvents.
Hydroxyethylmethacrylate (glycol methacrylate)'s viscosity is 0.0701 Pa⋅s at 20°C and 0.005 Pa⋅s at 30°C.
During polymerization, Hydroxyethylmethacrylate (glycol methacrylate) shrinks by approximately 6%.



ALTERNATIVE PARENTS OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
*Monocarboxylic acids and derivatives
*Primary alcohols
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
*Enoate ester
*Monocarboxylic acid or derivatives
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Primary alcohol
*Organooxygen compound
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound



PREPARATION OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) is a commercially important and widely used monomer.
Hydroxyethylmethacrylate (glycol methacrylate) is commonly prepared in a one-step reaction from methyl methacrylate or methacrylic acid.

Specifically, Hydroxyethylmethacrylate (glycol methacrylate) can be synthesized by the following two methods:
i. the first method involved the transesterification of ethylene glycol1;
ii. the second is the reaction between ethylene oxide and methacrylic acid2.

Several procedures were developed in order to remove the impurities in the production of Hydroxyethylmethacrylate (glycol methacrylate), such as soaking, extraction and ion-exchange.
As the major methacrylic derivative, Hydroxyethylmethacrylate (glycol methacrylate) can be polymerized by radical initiators or by various methods (γ-ray, UV, plasma, et. al).

Hydroxyethylmethacrylate (glycol methacrylate)'s primary –OH group allows the substitution reactions with the monomer or the corresponding polymer.
By adopting various techniques, the grafting of Hydroxyethylmethacrylate (glycol methacrylate)and copolymers prepared with HEMA as a comonomer has been performed with natural polymers such as cellulose, dextran, and starch.

In addition, synthetic polymers, polyethylene, polyurethanes, poly vinylic alcohol, blends of acrylic networks and polyvinylic alcohol, and polyesters also give grafting reactions whose aim is to improve the mechanical and physical properties of the initial products.

Hydroxyethylmethacrylate (glycol methacrylate) is inert, water-stable, and nondegradable with high transparency.
Because of its hydroxyethyl pendant groups, Hydroxyethylmethacrylate (glycol methacrylate) is widely prepared in the form of hydrogel to manufacture soft contact lenses.

Hydrogels generally absorb a large amount of water, and this swelling is responsible for the rubbery and soft properties of hydrogel.
Hydrogels have found applications in environmental, biomedical, food, etc., fields.

The physical properties of Hydroxyethylmethacrylate (glycol methacrylate) (e.g., swelling, stiffness, and rheology) can be tuned by varying cross-linking density, incorporating different chemistries through copolymerization, and introducing mesoscopic pores.

Specifically, a reduction in cross-linking density results in a softer, more malleable hydrogel that may be better suited for soft tissue regeneration.
Moreover, copolymerization with acetic acid, methylmethacrylate, or dextran can adjust the permanence, hydrophilicity, and cellular adhesion in vivo.
Finally, the introduction of mesoscopic porogens can facilitate vascular ingrowth, improve cellular attachment, and overcome limited permeability.

Although Hydroxyethylmethacrylate (glycol methacrylate) is considered nondegradable (which makes it ideally suited for long-term applications in vivo), degradable pHEMA copolymers have been fabricated by the integration of enzymatically susceptible monomers (e.g., dextran) or cross-linking agents.
These degradable materials show promise for controlled release of pharmaceuticals and proteins.



SYNTHESIS OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) was first synthesized around 1925.
Common methods of synthesis are:

*reaction of methacrylic acid with ethylene oxide;
*esterification of methacrylic acid with a large excess of ethylene glycol.

Both these methods give also some amount of ethylene glycol dimethacrylate.
During polymerization of Hydroxyethylmethacrylate (glycol methacrylate), it works as crosslinking agent.



PROPERTIES OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) is completely miscible with water and ethanol, but its polymer is practically insoluble in common solvents.
Hydroxyethylmethacrylate (glycol methacrylate)'s viscosity is 0.0701 Pa⋅s at 20°C and 0.005 Pa⋅s at 30°C.
During polymerization, Hydroxyethylmethacrylate (glycol methacrylate) shrinks by approximately 6%.



FUNCTION OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
*Abrasion Resistance
*Adhesion
*Cross-linker
*Low Color
*Low Odor
*Low Volatility
*Scratch Resistance



PROPERTIES OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
*Chemical resistance
*hydraulic stability
*flexibility
*impact resistance
*adhesion
*weather resistance



IT IS APPLIED IN THE PRODUCTION OF HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
Hydroxyethylmethacrylate (glycol methacrylate) is applied in the productıon of Coating resins, automotive coatings, architectural coatings,
paper coatings, industrial coatings, Plastics, hygiene products, adhesives and sealants, textile processes, printing inks, contact lenses, modifiers, photosensitive materials, and additives for petroleum production and transportation.



PHYSICAL and CHEMICAL PROPERTIES of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
EC no: 212-782-2
CAS no: 868-77-9
HS code: 29161400
KH product code: 100392
Formula: C6H10O3
Melting point:-12 °C
Boiling point: 67 °C3.5 mm Hg(lit.)
Density: 1.073 g/mL at 25 °C(lit.)
vapor density: 5 (vs air)
vapor pressure: 0.01 mm Hg ( 25 °C)
refractive index: n20/D
Molecular Weight:130.14200
Exact Mass:130.14
EC Number:212-782-2
UNII:6E1I4IV47V

ICSC Number:1724
NSC Number:24180
DSSTox ID:DTXSID7022128
NCI Thesaurus Code:C47791
Color/Form:Clear mobile liquid
HScode:2916140000
PSA:46.53000
XLogP3:0.5
Appearance:Liquid
Density:1.034 g/cm3 @ Temp: 25 °C
Melting Point:-12ºC
Boiling Point:67 °C @ Press: 3.5 Torr
Flash Point:64.043ºC
Refractive Index:1.441
Water Solubility:Solubility in water: miscible

Storage Conditions:2-8ºC
Vapor Pressure:0.01 mm Hg ( 25 °C)
Vapor Density:5 (vs air)
Experimental Properties:Heat of polymerization: 49.8 kJ/mole
Chemical Formula: C6H10O3
Molar Mass: 130.143 g/mol
Appearance: Colorless liquid
Density: 1.07 g/cm3
Melting Point: -99°C (-146°F; 174 K)
Boiling Point: 213°C (415°F; 486 K)
Solubility in Water: Miscible
Log P: 0.50
Vapor Pressure: 0.08 hPa



FIRST AID MEASURES of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of HYDROXYETHYLMETHACRYLATE (GLYCOL METHACRYLATE):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


Hydroxyethyl-Methyl Cellulose
HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE N° CAS : 93841-25-9 Nom INCI : HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE Nom chimique : 3-(2-Hydroxyethyl)-p-phenylenediammonium sulphate/ Hydroxyethyl-p- Phenylenediamine Sulfate N° EINECS/ELINCS : 298-995-1
HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE
HYDROXYLAMINE SULPHATE; Hydroxylammonium sulfate; Hydroxylamine, sulfate (2:1) (salt); bis(hydroxylamine) sulfate; hydroxylamine neutral sulfate; bis(hydroxylammonium) sulfate; Hydroxylamine sulfate; cas no: 10039-54-0
HYDROXYLAMINE SULFATE (HAS)
DESCRIPTION:

Hydroxylammonium sulfate [NH3OH]2SO4, is the sulfuric acid salt of hydroxylamine.
Hydroxylamine Sulfate (HAS) is primarily used as an easily handled form of hydroxylamine, which is explosive when pure.
Cyclohexanone oxime undergoes hydrolytic reaction with sulfuric acid to yield hydroxylamine sulfate.
Hydroxylamine Sulfate (HAS) reacts with sulfur dioxide to afford sulfamic acid.

CAS Number, 10039-54-0
EINECS, 233-118-8
Linear Formula:(NH2OH)2 • H2SO4




SYNONYM(S) OF HYDROXYLAMINE SULFATE (HAS):
Hydroxylammonium sulfate, HYDROXYLAMINE SULPHATE;HAS;HYDROXYLAMMONIUM SULPHATE;HYDROXYLAMMONIUM SULFATE;Hydroxyamine sulfate;Hydroxylammonium;Hydroxylammoniumsulfat;HuHAS1;amine suL;HA synthase,Hydroxylammonium sulfate,hydroxyazanium sulfate,Oxammonium sulfate,Hydroxylamine sulfate (2:1),hydroxyazanium;sulfate; Hydroxylammonium sulfate,hydroxyazanium sulfate,Oxammonium sulfate,Hydroxylamine sulfate (2:1),hydroxyazanium;sulfate,Hydroxylamine, sulfate,Bis(hydroxylamine) sulfate,Hydroxylamine neutral sulfate,bis(hydroxyazanium) sulfate,DTXSID2025424,49KP498D4O,bis(hydroxyammonium) sulfate,EINECS 233-118-8,Hydroxylammoniumsulfat,UN2865,Hydroxylamine, sulfate (2:1) (salt),LANASANE LAB,hydroxyl ammonium sulfate,hydroxyl ammonium sulphate,hydroxyl-ammonium sulphate,UNII-49KP498D4O,DTXCID505424,VGYYSIDKAKXZEE-UHFFFAOYSA-L,HYDROXYLAMINE SULFATE [MI],BIS(HYDROXYLAMMONIUM) SULFATE,HYDROXYLAMINE SULFATE [INCI],Tox21_202730,NCGC00091929-01,NCGC00260278-01,CAS-10039-54-0,NS00082564,EC 233-118-8,Hydroxylamine sulfate [UN2865] [Corrosive],Q416490




Hydroxylamine sulphate (HAS) is a white crystalline compound containing nitrogen with the formula of (NH2OH)2.
H2SO4 and is therefore an ammonia (NH3) like compound.
Hydroxylamine Sulfate (HAS) is soluble in water and is hygroscopic in nature.


SYNTHESIS OF HYDROXYLAMINE SULFATE (HAS):
Hydroxylammonium sulfate is prepared industrially via the Raschig hydroxylamine process, which involves the reduction of nitrite with bisulfite.
This initially gives hydroxylamine disulfonate, which is hydrolysed to hydroxylammonium sulfate:
It can also be obtained by the acid-base reaction of hydroxylamine with sulfuric acid:
2NH2OH(aq) + H2SO4(aq) → (NH3OH)2SO4(aq)


APPLICATIONS OF HYDROXYLAMINE SULFATE (HAS):
Hydroxylammonium sulfate is used in organic synthesis to convert aldehydes and ketones to oximes, carboxylic acids and their derivatives (e.g. esters) to hydroxamic acids, isocyanates to N-hydroxyureas and nitriles to amidoximes.
Hydroxylammonium sulfate is also used to generate hydroxylamine-O-sulfonic acid from oleum or chlorosulfuric acid.

Hydroxylammonium sulfate is used in the production of anti-skinning agents, pharmaceuticals, rubber, textiles, plastics and detergents.
Hydroxylamine Sulfate (HAS) is a radical scavenger that terminates radical polymerization reactions and serves as an antioxidant in natural rubber.
(NH3OH)2SO4 is a starting material for some insecticides, herbicides and growth regulators.

Hydroxylamine Sulfate (HAS) is used in photography as a stabiliser for colour developers and as an additive in photographic emulsions in colour film.

Decomposition:
At 120 °C, hydroxylammonium sulfate begins to decompose to sulfur trioxide, nitrous oxide, water, and ammonia[dubious – discuss]:
2(NH3OH)2SO4 → 2SO3 + N2O + 2NH3 + 5H2O

The reaction is exothermic above 138 °C, and is most exothermic at 177 °C.
Metals (especially copper, its alloys and its salts) catalyse the decomposition of hydroxylammonium sulfate.
The instability of this compound is mainly due to the hydroxylammonium ion's weak nitrogen to oxygen single bond.


USES OF HYDROXYLAMINE SULFATE (HAS):
Hydroxylamine Sulfate (HAS) is used as a viscosity stabilizer for natural rubber, and as a non-contaminating short-stopper for synthetic rubber.
A derivative of Hydroxylamine Sulfate (HAS) is also used as a vulcanizer.
Its many properties, including selective reactivity to textile fiber functional groups, make it useful for applications such as dye improvers, textile discoloration inhibitors, and modifiers for acrylic fibers and cellulose.
Other uses include resin improvers, UV stabilizers, and polymerization catalysts.

Hydroxylamine Sulfate (HAS) is used as a raw material for herbicides, insecticides, germicides, acaricides and other products in the form of derivatives of hydroxamic acid, hydroxy uric acid, carbamate, alkyl hydroxylamine, oxadiazole, and organophosphorous compounds, among others.

Hydroxylamine Sulfate (HAS) is also used as a raw material for germicides, CNS sedatives, antihistamines, sedatives, drugs for high blood sugar, wound infection inhibitors, diuretics, stimulants, blood coagulants, anti-malarial drugs, and diabetes drugs and other products in the form of derivatives of hydroxamic acid, hydroxy uric acid, isoxazole, oxadiazole, oxime, and amide, among others.
Due to its ability to reduce hydroxylamine sulfate and form metal complexes, HAS is used as a metal surface treatment agent, precipitant for separating metal, metal extractant, and rust proofer.


Hydroxylamine sulfate may be used in the following:

Along with NaCl for reduction during the atomic absorption spectrophotometric quantification of mercury at ppb (parts-per-billion) levels in solution.
As one of the constituents during the preparation of a coloring solution, impregnated in a cellulose based monitoring tape for the sensitive detection of formaldehyde gas.
Simultaneous estimation of hydrarine and hydroxylamine in mixtures by titration with alkaline ferricyanide in presence of zinc sulfate.



Also hydroxylammonium sulfate, or HS, (NH2OH)2•H2S04 is colorless crystals that are soluble in water and slightly soluble in alcohol.
The solution has a corrosive action on the skin.
Used as a reducing agent, photographic developer, purification agent for aldehydes and ketones, chemical synthesis, textile chemical, oxidation inhibitor for fatty acids, catalyst, in biological and biochemical research, for making oximes for paints and varnishes, and rustproofing.

Hydroxylammonium sulfate is a reducing agent in photography; catalyst, swelling agent, and copolymerization inhibitor in polymerization processes; in chemical synthesis; as a textile chemieal; as an oxidation inhibitor; in making oximes for paints and varnishes; in rustproofing; in nondiscoloring short -stoppers for synthetic rubbers; for unhairing hides; in biological and biochemical research; as a purification agent for aldehydes and ketones; converts aldehydes and ketones to oximes and acid chlorides to hydroxamic acids.


Hydroxylamine Sulfate (HAS) may be used to prepare highly sensitive cellulose tape, used for the detection of formaldehyde gas.
Hydroxylamine Sulfate (HAS) may be used in the quantitative determination of perchlorate in biological fluids by spectrophotometric methods .

Hydroxylamine Sulfate (HAS) may be used As reducing agent in photography; in synthetic and analytical chemistry; to purify aldehydes and ketones.
Hydroxylamine Sulfate (HAS) may be used As antioxidant for fatty acids and soaps.
Hydroxylamine Sulfate (HAS) may be used As dehairing agent for hides.


Hydroxylamine Sulfate (HAS) is Used as to purify aldehydes and ketones; reagent for mercury and silver detection in water; reducing agent.


Hydroxylamine Sulfate (HAS) is used as a viscosity stabilizer for natural rubber, and as a non-contaminating shortstopper for synthetic rubber.
A derivative of Hydroxylamine Sulfate (HAS) is also used as a vulcanizer.
Its many properties, including selective reactivity to textile fiber functional groups, make it useful for applications such as dye improvers, textile discoloration inhibitors, and modifiers for acrylic fibers and cellulose.

Other uses include resin improvers, UV stabilizers, and polymerization catalysts.
Due to its ability to reduce hydroxylamine sulfate and form metal complexes, Hydroxylamine Sulfate (HAS) is used as a metal surface treatment agent, precipitant for separating metal, metal extractant, and rust proofer.
Hydroxylamine Sulfate (HAS) is used as a raw material for herbicides, insecticides, germicides, acaricides and other products in the form of derivatives of hydroxamic acid, hydroxy uric acid, carbamate, alkyl hydroxylamine, oxadiazole, and organophosphorous compounds, among others.


CHEMICAL AND PHYSICAL PROPERTIES OF HYDROXYLAMINE SULFATE (HAS):
Chemical formula, H8N2O6S
Molar mass, 164.14 g/mol
Appearance, white crystalline to fine product, slightly hygroscopic
Density, 1.88 g/cm3
Melting point, 120 °C (248 °F; 393 K) decomposes
Solubility in water, 58.7 g/100 ml (20 °C)
Structure[1],
Crystal structure, Monoclinic
Space group, P21/c
Lattice constant, a = 7.932±0.002 Å, b = 7.321±0.002 Å, c = 10.403±0.003 Åα = 90°, β = 106.93±0.03°, γ = 90°
Formula units (Z), 4
Assay
99%
form
crystals
mp
170 °C (dec.) (lit.)
SMILES string
NO.NO.OS(O)(=O)=O
InChI
1S/2H3NO.H2O4S/c2*1-2;1-5(2,3)4/h2*2H,1H2;(H2,1,2,3,4)
InChI key
VRXOQUOGDYKXFA-UHFFFAOYSA-N
Melting point, 170 °C (dec.)(lit.)
Boiling point, 56.5℃
Density, 1.86
vapor pressure, 0.001Pa at 20℃
storage temp., -20°C
solubility, water: soluble(lit.)
form, Crystals
color, White
PH, 3.6 (10g/l, H2O, 20℃)
Water Solubility, 329 g/L (20 ºC)
Sensitive, Hygroscopic
Merck, 14,4828
Stability, Stable, but may be an explosion hazard - do not heat. May decompose explosively in the presence of alkalies. Air sensitive. Hygroscopic. Incompatible with copper, copper alloys, strong oxidising agents, strong bases, nitrites.
LogP, -1.031 (est)
CAS DataBase Reference, 10039-54-0(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances, HYDROXYLAMINE SULFATE
FDA 21 CFR, 175.105
EWG's Food Scores, 2-5
FDA UNII, 49KP498D4O
EPA Substance Registry System, Hydroxylamine sulfate (2:1) (10039-54-0)
CAS number, 10039-54-0
EC index number, 612-123-00-2
EC number, 233-118-8
Hill Formula, H₈N₂O₆S
Chemical formula, (HONH₃)₂SO₄
Molar Mass, 164.14 g/mol
HS Code, 2825 10 20
Density, 1.88 g/cm3 (20 °C)
Melting Point, 170 °C (decomposition)
pH value, 3.6 (10 g/l, H₂O, 20 °C)
Bulk density, 1100 kg/m3
Solubility, 587 g/l
Assay, ≥ 99 %
Chloride (Cl), ≤ 0.001 %
As (Arsenic), ≤ 0.00005 %
Cu (Copper), ≤ 0.0005 %
Fe (Iron), ≤ 0.0005 %
Hg (Mercury), ≤ 0.000001 %
Pb (Lead), ≤ 0.0005 %
Sulfated ash (residue on ignition), ≤ 0.1 %
Molecular Weight
164.14 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
6
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
164.01030715 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
164.01030715 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
184Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
9
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
64.2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
3
Computed by PubChem
Compound Is Canonicalized
Yes
Chemical Formula, (NH2OH)2-H2SO4
HX Concentration, 190-205 gm./lit.
Ammonium Sulphate, 400-440 gm./lit.
Acid Ratio, 1.15-1.20
pH, less than 1.0



SAFETY INFORMATION ABOUT HYDROXYLAMINE SULFATE (HAS)
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



Hydroxylamine
Hydroxylamine Sulfate; Hydroxylamine, sulfate (2:1) (salt); bis(hydroxylamine) sulfate; hydroxylamine neutral sulfate; bis(hydroxylammonium) sulfate; Hydroxylamine sulfate; OXAMMONIUM SULFATE cas no: 10039-54-0
Hydroxylamine Sulfate
SYNONYMS Hydroxylammonium sulfate; Hydroxylamine, sulfate (2:1) (salt); bis(hydroxylamine) sulfate; hydroxylamine neutral sulfate; bis(hydroxylammonium) sulfate; Hydroxylamine sulfate;OXAMMONIUM SULFATE CAS NO. 10039-54-0
HYDROXYLAMMONIUM SULFATE (HAS)

Hydroxylammonium sulfate (HAS) is a chemical compound with the formula NH3OHHSO4.
Hydroxylammonium sulfate (HAS) is also known as hydroxylamine sulfate or oxammonium sulfate.
Hydroxylammonium sulfate (HAS) is a salt that contains hydroxylamine, a derivative of ammonia, and sulfuric acid.
Hydroxylammonium sulfate (HAS) is commonly used in various industrial processes, such as in the synthesis of pharmaceuticals, pesticides, and other organic compounds.

CAS Number: 10039-54-0
EC Number: 233-118-8



APPLICATIONS


Hydroxylammonium sulfate (HAS) serves as a crucial reducing agent in the pharmaceutical industry, aiding in the synthesis of various drugs, including antimalarials and antibiotics.
Hydroxylammonium sulfate (HAS) is an essential component in the production of agricultural chemicals, contributing to the formulation of pesticides and herbicides.
Hydroxylammonium sulfate (HAS) finds use in the preparation of photographic developers, ensuring image stability during film processing.

Hydroxylammonium sulfate (HAS) acts as a key ingredient in the creation of explosives, contributing to their synthesis.
Its application extends to the production of polymers and plastics, where it plays a role in the manufacturing process.
Hydroxylammonium sulfate (HAS) is employed in the electroplating industry, facilitating the deposition of certain metals onto surfaces.

Water treatment processes utilize HAS as a reducing agent to eliminate certain contaminants.
Its role in dye production involves acting as a reducing agent in colorant synthesis.
Hydroxylammonium sulfate (HAS) is employed in laboratories for various chemical analyses, including in redox reactions and experimental setups.
Hydroxylammonium sulfate (HAS) is utilized in the synthesis of oximes, which serve as intermediates in the creation of organic compounds.
Hydroxylammonium sulfate (HAS) assists in the creation of specialty chemicals used in industries such as cosmetics and personal care products.

In the production of antioxidants, HAS is used as a reactant in specific formulations.
Hydroxylammonium sulfate (HAS) aids in the formulation of select pharmaceutical intermediates due to its reductive properties.
Hydroxylammonium sulfate (HAS) serves as a stabilizer in the creation of certain explosives, contributing to their safe storage and handling.
Industries engaged in metallurgy use HAS to purify and extract certain metals from ores.
Its application in the synthesis of insecticides is integral to pest control strategies in agriculture.
Hydroxylammonium sulfate (HAS) assists in the production of rubber chemicals, contributing to the manufacturing process.

Hydroxylammonium sulfate (HAS) is used in the creation of color photographic materials, contributing to image development and stability.
Hydroxylammonium sulfate (HAS) plays a role in the synthesis of various organic intermediates and compounds in the chemical industry.
Its use in the creation of antioxidants supports the preservation of various materials susceptible to oxidation.

Hydroxylammonium sulfate (HAS) aids in the formulation of specialty chemicals used in the electronics industry.
Hydroxylammonium sulfate (HAS) contributes to the creation of chelating agents used in various industrial processes.

In the field of medicine, HAS plays a role in the synthesis of certain diagnostic agents.
Its application in the formulation of specialty chemicals extends to the creation of surfactants used in cleaning products.
Hydroxylammonium sulfate (HAS) is integral in several industrial processes due to its versatile reductive properties, finding application across diverse sectors.

In the creation of antioxidants, HAS is pivotal in protecting materials from oxidative degradation in various industries.
Hydroxylammonium sulfate (HAS) plays a role in the synthesis of pharmaceuticals, aiding in the creation of cardiovascular and antitumor medications.

Its use in the production of agrochemicals supports advancements in crop protection and agricultural practices.
Hydroxylammonium sulfate (HAS) aids in the formulation of specialty chemicals used in the synthesis of fragrance and flavor compounds.
Hydroxylammonium sulfate (HAS) serves as a stabilizer in the manufacture of certain dyes, ensuring color stability and quality.
In the creation of rubber accelerators, HAS contributes to the enhancement of rubber production processes.

Hydroxylammonium sulfate (HAS)'s reductive properties make it vital in the formulation of antioxidants for food preservation.
Hydroxylammonium sulfate (HAS) is instrumental in the creation of intermediates used in the production of adhesives and sealants.

Its role in the synthesis of corrosion inhibitors supports the preservation of metals in various applications.
Hydroxylammonium sulfate (HAS) contributes to the creation of specialty chemicals used in the formulation of hair dyes and cosmetics.
Hydroxylammonium sulfate (HAS) aids in the creation of catalysts used in various chemical reactions and industrial processes.

Hydroxylammonium sulfate (HAS) is employed in the synthesis of specialty chemicals for the textile industry, contributing to dye and pigment formulations.
Its utility in the production of herbicides supports weed control and agricultural productivity.

Hydroxylammonium sulfate (HAS) assists in the creation of specialty chemicals for water treatment, aiding in purification processes.
In the field of biotechnology, HAS serves as a reagent in various research and experimental setups.
Hydroxylammonium sulfate (HAS)'s involvement in the creation of imaging agents supports advancements in medical diagnostics.

Hydroxylammonium sulfate (HAS) contributes to the synthesis of chelating agents used in metal extraction and purification processes.
Its use in the production of antioxidants aids in preserving the quality of oils and fats.
Hydroxylammonium sulfate (HAS) plays a role in the creation of chemical intermediates used in the formulation of surfactants for cleaning products.

Hydroxylammonium sulfate (HAS)'s reductive properties are harnessed in the creation of flame retardants for various materials.
Hydroxylammonium sulfate (HAS) contributes to the formulation of specialty chemicals used in the creation of pigments and colorants.
Its use in the synthesis of intermediates for the pharmaceutical industry supports drug development.

In the creation of specialty chemicals for the electronics industry, HAS aids in the formulation of certain compounds.
Hydroxylammonium sulfate (HAS)'s involvement in the creation of antioxidants supports the preservation of cosmetic formulations.
Hydroxylammonium sulfate (HAS) is indispensable in various industrial processes due to its versatility and reductive capabilities, influencing numerous sectors and applications.

Hydroxylammonium sulfate (HAS) is used in the synthesis of specialty chemicals crucial in the production of adhesives and sealants for various industries.
Its involvement in the creation of specialty chemicals supports advancements in the production of pharmaceutical intermediates.
Hydroxylammonium sulfate (HAS) serves as a stabilizer in the formulation of certain dyes, contributing to color quality and consistency.

In the field of agriculture, HAS aids in the creation of insecticides, supporting pest control strategies.
Hydroxylammonium sulfate (HAS) is involved in the creation of specialty chemicals used in the production of corrosion inhibitors for metal preservation.
Hydroxylammonium sulfate (HAS) assists in the formulation of antioxidants, ensuring the protection of various materials susceptible to oxidation.
In the creation of rubber chemicals, HAS contributes to the enhancement of rubber manufacturing processes.

Hydroxylammonium sulfate (HAS)'s reductive properties are harnessed in the creation of intermediates used in the pharmaceutical industry.
Hydroxylammonium sulfate (HAS) plays a role in the formulation of specialty chemicals used in the creation of fragrance and flavor compounds.
Its involvement in the production of agrochemicals supports advancements in agricultural practices and crop protection.

Hydroxylammonium sulfate (HAS) contributes to the creation of antioxidants crucial for preserving food quality and extending shelf life.
In the production of herbicides, HAS supports weed control strategies and agricultural productivity.
Hydroxylammonium sulfate (HAS) aids in the synthesis of specialty chemicals used in the textile industry for dye and pigment formulations.
Hydroxylammonium sulfate (HAS) serves as a reagent in biotechnological research and experimental setups.

Its involvement in the creation of imaging agents supports advancements in medical diagnostics and imaging technologies.
Hydroxylammonium sulfate (HAS) is integral in the creation of chelating agents used in metal extraction and purification processes.
Its use in the synthesis of flame retardants supports the safety and fire resistance of various materials.

Hydroxylammonium sulfate (HAS) contributes to the formulation of specialty chemicals used in the creation of pigments and colorants.
Hydroxylammonium sulfate (HAS) plays a role in the synthesis of intermediates used in the formulation of surfactants for cleaning products.
In the electronics industry, HAS aids in the formulation of specialty chemicals for certain compounds.
Its involvement in the creation of antioxidants supports the preservation and stability of cosmetic formulations.
Hydroxylammonium sulfate (HAS) is crucial in various industrial processes due to its versatility and influence across multiple sectors.

Hydroxylammonium sulfate (HAS)'s use as a reducing agent is vital in various chemical reactions and processes.
Hydroxylammonium sulfate (HAS) contributes to the creation of specialty chemicals used in the production of pharmaceuticals and other organic compounds.
Its applications across diverse industries highlight the compound's versatility and importance in numerous sectors.

Hydroxylammonium sulfate (HAS) plays a crucial role in the synthesis of pharmaceutical intermediates, contributing to the production of vital medications.
In the agricultural sector, HAS is utilized in the formulation of pesticides, supporting crop protection and agricultural productivity.
Hydroxylammonium sulfate (HAS) aids in the stabilization of images in photographic development processes, ensuring quality and consistency.

Its involvement in the creation of explosives contributes to their synthesis and stability in certain formulations.
Hydroxylammonium sulfate (HAS) serves as an essential component in the production of polymers and plastics, influencing manufacturing processes.
Its application in electroplating processes contributes to the deposition of metals onto surfaces.
Water treatment processes utilize HAS as a reducing agent to eliminate specific contaminants.

Hydroxylammonium sulfate (HAS) is integral in dye production, acting as a reducing agent in the synthesis of various colorants.
Hydroxylammonium sulfate (HAS) is employed in laboratories for diverse chemical analyses and experimental setups.
Hydroxylammonium sulfate (HAS) plays a role in the synthesis of oximes, essential intermediates in organic compound synthesis.

Hydroxylammonium sulfate (HAS) assists in the creation of specialty chemicals used in industries such as cosmetics and personal care.
In the production of antioxidants, HAS is used as a reactant in specific formulations.
Its reductive properties are essential in the creation of pharmaceutical intermediates.

Hydroxylammonium sulfate (HAS) serves as a stabilizer in the production of certain explosives, aiding in their safe storage and handling.
In metallurgical processes, HAS is used to purify and extract specific metals from ores.
Its role in the synthesis of insecticides is pivotal in pest control strategies.
Hydroxylammonium sulfate (HAS) is utilized in the creation of rubber chemicals, influencing manufacturing processes.
Its use in the creation of color photographic materials is crucial in image development and stability.

Hydroxylammonium sulfate (HAS) is employed in the synthesis of organic intermediates and compounds in the chemical industry.
Its reductive properties are utilized in water treatment processes to eliminate contaminants.
Hydroxylammonium sulfate (HAS) is used as a catalyst in certain chemical reactions, influencing reaction rates.

Hydroxylammonium sulfate (HAS)'s reactivity necessitates cautious storage and handling protocols.
Its use in dye production is crucial for various industries reliant on colorants.
Hydroxylammonium sulfate (HAS) finds applications in diverse industrial processes, owing to its versatile reductive properties.
Understanding Hydroxylammonium sulfate (HAS)'s properties is crucial for ensuring safe and effective use in various industrial and scientific contexts.

Hydroxylammonium sulfate (HAS) is pivotal in the synthesis of pharmaceutical intermediates, contributing to the production of crucial medications.
Its use in the agricultural sector involves the formulation of pesticides, supporting crop protection and agricultural productivity.

In photographic development, HAS stabilizes images, ensuring quality and consistency in printed materials.
Its involvement in the creation of explosives contributes to their synthesis and stability in certain formulations.
Hydroxylammonium sulfate (HAS) is an essential component in the production of polymers and plastics, influencing manufacturing processes.
Its application in electroplating processes contributes to the deposition of metals onto various surfaces.

Water treatment processes rely on HAS as a reducing agent to eliminate specific contaminants.
Hydroxylammonium sulfate (HAS)'s role in dye production involves acting as a reducing agent in the synthesis of various colorants.
Hydroxylammonium sulfate (HAS) is employed in laboratories for diverse chemical analyses and experimental setups.

Hydroxylammonium sulfate (HAS) plays a critical role in the synthesis of oximes, which are essential intermediates in organic compound synthesis.
Hydroxylammonium sulfate (HAS) contributes to the creation of specialty chemicals used in industries such as cosmetics and personal care.
In the production of antioxidants, HAS is a key reactant in specific formulations.
Its reductive properties are crucial in the creation of pharmaceutical intermediates.

Hydroxylammonium sulfate (HAS) serves as a stabilizer in the production of certain explosives, aiding in their safe storage and handling.
In metallurgical processes, HAS is used to purify and extract specific metals from ores.
Its role in the synthesis of insecticides is pivotal in pest control strategies.
Hydroxylammonium sulfate (HAS) is utilized in the creation of rubber chemicals, influencing various manufacturing processes.
Its use in the creation of color photographic materials is crucial for image development and stability.

Hydroxylammonium sulfate (HAS) finds applications in the synthesis of organic intermediates and compounds in the chemical industry.
Its reductive properties are effectively utilized in water treatment processes to eliminate contaminants.
Hydroxylammonium sulfate (HAS) serves as a catalyst in certain chemical reactions, significantly influencing reaction rates.
Due to its reactivity, proper storage and handling protocols are essential for HAS.
Its use in dye production is vital for industries reliant on various colorants.

Hydroxylammonium sulfate (HAS)'s versatile reductive properties are crucial for diverse industrial processes.
Comprehensive understanding of HAS's properties ensures its safe and effective use in various industrial and scientific contexts.



DESCRIPTION


Hydroxylammonium sulfate (HAS) is a chemical compound with the formula NH3OHHSO4.
Hydroxylammonium sulfate (HAS) is also known as hydroxylamine sulfate or oxammonium sulfate.
Hydroxylammonium sulfate (HAS) is a salt that contains hydroxylamine, a derivative of ammonia, and sulfuric acid.
Hydroxylammonium sulfate (HAS) is commonly used in various industrial processes, such as in the synthesis of pharmaceuticals, pesticides, and other organic compounds.

Hydroxylammonium sulfate (HAS) is a versatile compound that's utilized in diverse applications, including as a reducing agent in chemical processes, as a stabilizer in photographic developers, and in certain agricultural formulations.
Its ability to undergo redox reactions makes it valuable in several chemical and industrial contexts.
However, Hydroxylammonium sulfate (HAS) should be handled with care due to its potential reactivity and the fact that it can be hazardous if not properly managed.

Hydroxylammonium sulfate (HAS) is a crystalline compound with a white, granular appearance.
Its chemical structure comprises hydroxylamine molecules bonded with sulfate ions.
Hydroxylammonium sulfate (HAS) is known for its versatile utility as a reducing agent in various chemical reactions.

Hydroxylammonium sulfate (HAS) finds application in the synthesis of pharmaceuticals, including antibiotics and antimalarial drugs.
Hydroxylammonium sulfate (HAS) is integral in the production of agricultural chemicals, aiding in the creation of pesticides and herbicides.
Hydroxylammonium sulfate (HAS) is a crucial ingredient in photographic developers, contributing to image stabilization during film development.
Due to its reactivity, HAS requires careful handling to prevent potential hazards.

Hydroxylammonium sulfate (HAS) undergoes redox reactions, wherein it acts as both an oxidizing and reducing agent in different chemical contexts.
Hydroxylammonium sulfate (HAS) has a characteristic odor, reminiscent of ammonia, due to its ammonia-based derivative.

Hydroxylammonium sulfate (HAS) plays a role in the formation of explosives by serving as a component in their synthesis.
Its water-soluble nature allows for ease in dissolution and use in aqueous solutions.

Hydroxylammonium sulfate (HAS) possesses hygroscopic properties, absorbing moisture from the air.
Hydroxylammonium sulfate (HAS) has a relatively high melting point, indicating its stability under moderate heat conditions.
Hydroxylammonium sulfate (HAS)'s versatility extends to applications in analytical chemistry and electroplating processes.

Hydroxylammonium sulfate (HAS) serves as a precursor in the production of oximes, essential in the synthesis of various organic compounds.
Hydroxylammonium sulfate (HAS)'s properties are harnessed in industries for the creation of polymers and plastics.

Hydroxylammonium sulfate (HAS) exhibits a high degree of stability when stored under recommended conditions.
Due to its potential reactivity, Hydroxylammonium sulfate (HAS) demands cautious storage and handling protocols.
Its utility as a reducing agent extends to diverse industries, including those focused on dye production.

Hydroxylammonium sulfate (HAS)'s use in laboratories aids in various chemical analyses and experimental setups.
Hydroxylammonium sulfate (HAS) can act as a catalyst in certain chemical reactions, influencing the rate of reaction without being consumed.
Hydroxylammonium sulfate (HAS)'s reductive properties find application in water treatment processes.

Hydroxylammonium sulfate (HAS) is subject to regulatory control due to its potential environmental and health impacts.
Hydroxylammonium sulfate (HAS)'s reactivity necessitates careful attention to its compatibility with other substances in various processes.
Understanding the properties and applications of Hydroxylammonium sulfate (HAS) is crucial for ensuring safe and effective utilization in diverse industrial and scientific contexts.



PROPERTIES


Chemical Formula: NH3OHHSO4
Molecular Weight: Approximately 164.14 g/mol
Appearance: White crystalline solid or granules
Odor: Characteristic ammonia-like odor
Solubility: Highly soluble in water
Hygroscopicity: Absorbs moisture from the air
Melting Point: Around 170-175°C (338-347°F)
Density: Varies with crystalline form
Reactivity: Acts as a reducing agent in various chemical reactions
Stability: Relatively stable under recommended storage conditions
Redox Properties: Exhibits both oxidizing and reducing characteristics
Toxicity: Can be hazardous if ingested or inhaled; irritant to skin and eyes



FIRST AID


Inhalation:

Move to Fresh Air:
If inhaled, promptly move the affected person to an area with fresh air.

Seek Medical Attention:
If respiratory symptoms persist or if there's difficulty in breathing, seek immediate medical attention.

Provide Oxygen:
If the person has difficulty breathing, administer oxygen if trained to do so and if available.

Keep Calm and Monitor:
Stay with the individual and monitor their breathing and vital signs until medical help arrives.


Skin Contact:

Remove Contaminated Clothing:
If HAS comes into contact with the skin, remove contaminated clothing immediately.

Rinse with Water:
Thoroughly rinse the affected skin area with plenty of water for at least 15 minutes.

Mild Soap Use:
Use mild soap to cleanse the area affected.

Seek Medical Help:
If irritation, redness, or other symptoms persist, seek medical attention.


Eye Contact:

Flush Eyes with Water:
If HAS contacts the eyes, immediately flush them with gently flowing water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing.

Seek Medical Help:
Seek medical assistance or eye care professional immediately after rinsing.


Ingestion:

Do NOT Induce Vomiting:
Do not induce vomiting unless instructed by medical personnel.

Rinse Mouth:
If the individual is conscious, rinse their mouth and provide small sips of water.

Seek Medical Attention:
Immediately seek medical assistance or contact a Poison Control Center.

Provide Medical Information:
Provide the medical personnel with the chemical's name, its Safety Data Sheet, and the details of the exposure.



HANDLING AND STORAGE


Handling:

Personal Protection Equipment (PPE):
Wear appropriate protective gear, including chemical-resistant gloves, safety goggles or a face shield, and a lab coat or protective clothing to minimize skin contact.

Ventilation:
Work in a well-ventilated area or use fume hoods to minimize inhalation of fumes or vapors.

Handling Precautions:
Avoid direct contact with skin, eyes, and clothing.
Prevent inhalation by using appropriate respiratory protection if working in an area with potential airborne exposure.
Prevent ingestion.
Do not eat, drink, or smoke in areas where HAS is being handled.

Spills and Leaks:
In case of spills, wear protective gear and contain the spill using absorbent materials.
Collect spilled material and dispose of it in accordance with local regulations.

Avoid Mixing:
Do not mix HAS with incompatible substances, such as strong acids or oxidizers, which might lead to hazardous reactions.

Storage Compatibility:
Store HAS away from incompatible materials and sources of heat or ignition.


Storage:

Storage Area:
Store HAS in a cool, dry, well-ventilated area.
Ensure the storage area is equipped with adequate fire suppression equipment.
Keep the area secure and inaccessible to unauthorized personnel, especially if the compound is hazardous.

Temperature Conditions:
Store at ambient temperature (around 20-25°C or 68-77°F).
Keep away from extreme heat or direct sunlight to avoid degradation.

Containers:
Use tightly sealed containers made of suitable material that can withstand the chemical.
Glass or plastic containers may be appropriate.
Ensure containers are labeled clearly with the chemical name, hazard warnings, and handling instructions.

Separation and Segregation:
Store HAS away from acids, oxidizers, and other incompatible substances.

Handling Precautions:
During storage, regularly inspect containers for any signs of damage, leaks, or corrosion.
Replace damaged containers immediately.

Regulatory Compliance:
Adhere to local, regional, and national regulations regarding the storage of hazardous substances.
Comply with safety guidelines and laws.

Emergency Preparedness:
Have a spill containment kit and appropriate personal protective equipment readily available in the storage area.
Establish and communicate emergency procedures in case of accidental exposure, spills, or other emergencies.



SYNONYMS


Hydroxylamine sulfate
Oxammonium sulfate
Sulfate de hydroxylamine (in French)
Hydroxylammonium sulphate
Sulfuric acid hydroxylamine salt
Ammonium hydroxide sulfate
Hydroxylammonium hydrogen sulfate
Hydroxylammonium sulphate
Hydroxylammonium hydrogen sulphate
Hydroxylamine hydrogen sulfate
Oxammonium hydrogen sulfate
Sulfuric acid oxammonium salt
Ammonium hydroxide hydrogen sulfate
Hydroxylamine bisulfate
Sulfate de hydroxylamine (French)
Sulfato de hidroxilamina (Spanish)
Hydroxylamine bisulphate
Ammonium hydroxylate sulfate
Hydroxylamine sulfuric acid salt
Hydroxylammonium hydrogen sulphate
Hydroxylamine sulphate
Ammonium hydroxide sulphate
Sulfuric acid hydroxylamine
Hydroxylammonium acid sulfate
Sulfate de l'hydroxylamine (French)
Hidroxilamina sulfato (Portuguese)
Hydroxylamine sulphuric salt
Sulfuric acid ammonium hydroxide
Hydroxylammonium hydrogen sulfuric acid
Bisulfate de hydroxylamine
Ammonium sulfate of hydroxylamine
Hydroxylamine acid sulfate
Sulfato de hidroxilammonio (Spanish)
Ammonium sulfate hydroxylamine
Hydroxylamine acid hydrogen sulfate
Sulfuric acid hydroxylamine salt
Hydroxylammonium bisulfate
Ammonium hydroxylamine sulfate
Hydroxylamine sulphuric acid salt
Hydroxylamine sulfate monohydrate
Sulfate d'hydroxylammonium (French)
Hydroxylammonium sulfuric acid
Ammonium hydroxylamine sulphate
Hydroxylamine hydrogen sulphate
Sulfate de l'hydroxylamine (French)
Hydroxylamine sulfuric acid salt
Bisulfate d'hydroxylamine (French)
Hydroxylammonium sulfate hydrate
Sulfuric acid ammonium hydroxylamine
Hydroxylamine acid sulfuric salt
Hydroxylamine hydrogen sulfuric acid
Sulfato de hidroxilamina (Portuguese)
Hydroxylamine hydrogen sulfuric salt
Sulfate d'hydroxylamine (French)
Ammonium hydroxylamine hydrogen sulfate
Hydroxylamine sulfate salt
Hydroxylammonium hydrogen sulphuric acid
Bisulfate de l'hydroxylamine (French)
Sulfate d'hydroxylamine (French)