GLYCERETH-7, N° CAS : 31694-55-0, Nom INCI : GLYCERETH-7, N° EINECS/ELINCS : 500-075-4, Classification : Composé éthoxylé. Ses fonctions (INCI). Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

GLYCERETH-7 BENZOATE, N° CAS : 139247-28-2, Nom INCI : GLYCERETH-7 BENZOATE. Classification : Composé éthoxylé. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau, Solvant : Dissout d'autres substances

GLYCERETH-7 CAPRYLATE/CAPRATE. Nom INCI : GLYCERETH-7 CAPRYLATE/CAPRATE. Classification : Composé éthoxylé. Ses fonctions (INCI). Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Sinergiste de mousse : Améliore la qualité de la mousse produite en augmentant une ou plusieurs des propriétés suivantes: volume, texture et / ou stabilité. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien de la peau : Maintient la peau en bon état. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

GLYCERETH-7 COCOATE, Nom INCI : GLYCERETH-7 COCOATE. Classification : Composé éthoxylé. Ses fonctions (INCI). Agent nettoyant : Aide à garder une surface propre. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance.Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau Agent d'entretien de la peau : Maintient la peau en bon état. Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

GLYCERETH-7 TRIACETATE, N° CAS : 57569-76-3. Nom INCI : GLYCERETH-7 TRIACETATE. Classification : Composé éthoxylé. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau Solvant : Dissout d'autres substances

GLYCERINE; Glycerol; 1,2,3-Propanetriol; Glyceritol; Glycic Alcohol; 1,2,3-Trihydroxypropane; Trihydroxypropane; Clyzerin, Wasserfrei; Glyrol; Glysanin; Grocolene; cas no: 56-81-5

Glycerin tripalmitate is a white, solid compound with a waxy texture.
Glycerin tripalmitate has a characteristic odor and is odorless.

CAS number: 555-44-2
EC number: 209-008-0



APPLICATIONS


Glycerin tripalmitate is commonly used as a texturizer and stabilizer in the production of margarine and spreads.
Glycerin tripalmitate enhances the smoothness, spreadability, and mouthfeel of food products.
Glycerin tripalmitate acts as an emulsifier in bakery products, helping to blend fat and water-based ingredients.

Glycerin tripalmitate is utilized in the formulation of confectionery, providing a creamy texture and improving shelf stability.
Glycerin tripalmitate serves as a moisturizing and emollient agent in skincare products such as creams, lotions, and balms.
Glycerin tripalmitate helps prevent moisture loss from the skin, keeping it hydrated and supple.

Glycerin tripalmitate finds application in lipsticks, providing a smooth application and long-lasting wear.
Glycerin tripalmitate is used as a binder in pharmaceutical tablet formulations, ensuring the integrity and strength of the tablets.
Glycerin tripalmitate is employed in solid dosage forms such as capsules, providing controlled release of active ingredients.

Glycerin tripalmitate acts as a lubricant in industrial applications, reducing friction and improving machinery performance.
Glycerin tripalmitate is utilized in metalworking processes to enhance machining operations and reduce wear on cutting tools.

Glycerin tripalmitate finds application as a mold release agent in manufacturing processes, preventing sticking or adhesion.
Glycerin tripalmitate is used in the formulation of printing inks, providing smoothness and gloss to the printed surface.

Glycerin tripalmitate acts as a carrier or matrix material in encapsulation processes, protecting and controlling the release of active ingredients.
Glycerin tripalmitate is employed in the production of candles, improving burn time, texture, and fragrance retention.
Glycerin tripalmitate serves as a coating ingredient in paint formulations, enhancing adhesion and durability.

Glycerin tripalmitate finds application as a release agent in the production of rubber and plastic products, facilitating demolding.
Glycerin tripalmitate is used in the formulation of polishes and waxes for surfaces such as wood and leather, providing shine and protection.
Glycerin tripalmitate serves as a lubricant and processing aid in the plastic industry, aiding in molding and extrusion processes.

Glycerin tripalmitate acts as an adhesive component in industrial adhesives, providing tackiness and bonding properties.
Glycerin tripalmitate is used in animal feed formulations, serving as a concentrated energy source for livestock.

Glycerin tripalmitate finds application in the research and development of lipid-based drug delivery systems.
Glycerin tripalmitate is utilized in the study of emulsion science and formulation of stable emulsions for various applications.

Glycerin tripalmitate serves as a calibration standard in analytical techniques such as chromatography and spectroscopy.
Glycerin tripalmitate has versatile applications in food, cosmetics, pharmaceuticals, industrial processes, and research, making it a valuable compound in multiple industries.
Glycerin tripalmitate is used as a plasticizer in the plastic industry, improving flexibility and reducing brittleness in plastic materials.

Glycerin tripalmitate finds application in the formulation of adhesives for woodworking and construction purposes.
Glycerin tripalmitate is utilized in the production of wax-based coatings for surfaces such as paper, cardboard, and textiles.

Glycerin tripalmitate serves as a conditioning agent in hair care products, providing softness and manageability to the hair.
Glycerin tripalmitate is used in the formulation of lip balms, providing hydration and protection to the lips.

Glycerin tripalmitate finds application in the production of ointments and creams for pharmaceutical and dermatological use.
Glycerin tripalmitate is utilized in the formulation of sunscreen products, enhancing the dispersion of UV filters and improving their efficacy.
Glycerin tripalmitate is employed in the production of pressed powders in the cosmetic industry, providing binding and smoothing properties.

Glycerin tripalmitate serves as a lubricant in the processing of polymers, facilitating extrusion and injection molding.
Glycerin tripalmitate finds application in the production of resin-based art materials, providing texture and workability.
Glycerin tripalmitate is used as a film-forming agent in the coating of tablets to improve swallowability and mask unpleasant tastes.

Glycerin tripalmitate finds application in the production of solid perfumes, providing a long-lasting fragrance release.
Glycerin tripalmitate is utilized in the formulation of stick foundations, providing a creamy texture and smooth application.
Glycerin tripalmitate acts as a suspending agent in oral suspensions, helping to disperse insoluble particles uniformly.
Glycerin tripalmitate finds application in the production of suppositories, enhancing their stability and ease of insertion.

Glycerin tripalmitate serves as a lubricant and release agent in the production of rubber goods and molded parts.
Glycerin tripalmitate is used in the formulation of personal lubricants, providing smoothness and reducing friction during intimate activities.
Glycerin tripalmitate finds application in the production of specialty soaps, contributing to their texture and cleansing properties.
Glycerin tripalmitate is utilized in the formulation of wax-based crayons, improving color transfer and durability.

Glycerin tripalmitate acts as a spreading agent in agricultural applications, aiding the uniform distribution of pesticides and fertilizers.
Glycerin tripalmitate finds application in the production of biodegradable plastics, contributing to their mechanical and thermal properties.

Glycerin tripalmitate is used in the formulation of pharmaceutical creams and gels for topical drug delivery.
Glycerin tripalmitate finds application in the production of flavor and fragrance encapsulation systems, improving stability and release characteristics.
Glycerin tripalmitate serves as a carrier for fat-soluble vitamins and nutraceuticals in food and dietary supplements.
Glycerin tripalmitate is utilized in the production of specialty inks, such as those used for gravure printing and flexography.


Glycerin tripalmitate (tripalmitin) has several applications across different industries.
Some of its main applications include:

Food Industry:
Glycerin tripalmitate is used as a food additive and ingredient.
Glycerin tripalmitate serves as a texturizer, stabilizer, and emulsifier in various food products, such as margarine, spreads, baked goods, confectionery, and processed meats.

Cosmetics and Personal Care:
Glycerin tripalmitate is widely used in cosmetics and personal care products.
Glycerin tripalmitate is employed as a thickening agent, emollient, and moisturizer in creams, lotions, balms, lipsticks, and other skincare formulations.

Pharmaceuticals:
Glycerin tripalmitate finds application in the pharmaceutical industry.
Glycerin tripalmitate is utilized as a binder in tablet formulations, helping to hold the active ingredients together and provide cohesive tablets.

Industrial Lubricants:
Glycerin tripalmitate has lubricating properties, making it suitable for use in industrial lubricants, greases, and cutting fluids.
Glycerin tripalmitate helps reduce friction and enhance the performance of machinery and equipment.

Research and Development:
Glycerin tripalmitate is utilized in research and development activities as a standard reference material.
Glycerin tripalmitate serves as a calibration standard for analytical techniques, such as chromatography and spectroscopy.

Encapsulation:
Glycerin tripalmitate is used in encapsulation processes, where it acts as a carrier or matrix material for encapsulating active ingredients, flavors, or fragrances.
Glycerin tripalmitate helps protect the encapsulated substances and control their release.

Coatings and Inks:
Glycerin tripalmitate can be found in coatings and inks, particularly in the formulation of wax-based coatings and printing inks.
Glycerin tripalmitate imparts gloss, smoothness, and moisture resistance to the coatings and inks.

Industrial Applications:
Glycerin tripalmitate is employed in various industrial applications, including metalworking, lubricant additives, plasticizers, and mold release agents.

Candle Making:
Glycerin tripalmitate is utilized in candle making as a component of wax formulations.
Glycerin tripalmitate helps improve the texture, burn time, and fragrance retention of candles.

Paints and Coatings:
Glycerin tripalmitate is employed in the formulation of paints and coatings, particularly in oil-based systems.
Glycerin tripalmitate acts as a binder, providing adhesion and durability to the paint film.

Release Agent:
Glycerin tripalmitate is used as a release agent in various manufacturing processes.
Glycerin tripalmitate helps prevent sticking or adhesion of materials to molds, surfaces, or equipment during production.

Polishing and Finishing Products:
Glycerin tripalmitate is found in polishes, waxes, and finishing products for surfaces such as wood, leather, and furniture.
Glycerin tripalmitate enhances the shine, protection, and smoothness of these surfaces.

Industrial Adhesives:
Glycerin tripalmitate is utilized in the formulation of industrial adhesives, providing tackiness and adhesive properties to the products.

Plastic Industry:
Glycerin tripalmitate finds application in the plastic industry as a lubricant, processing aid, and anti-blocking agent during plastic molding and extrusion processes.

Animal Nutrition:
Glycerin tripalmitate is used in animal feed formulations.
Glycerin tripalmitate provides a concentrated source of energy and helps improve the texture and palatability of feed pellets.

Research and Development:
Glycerin tripalmitate is used in various research and development applications, including lipid studies, emulsion science, and drug delivery systems.

Surfactant Systems:
Glycerin tripalmitate can be employed as an ingredient in surfactant systems, where it helps stabilize emulsions and improve the texture of personal care and household cleaning products.

Seed Coating:
Glycerin tripalmitate is utilized in seed coating formulations to improve the flowability, dispersibility, and adherence of active ingredients onto seeds.



DESCRIPTION


Glycerin tripalmitate is a white, solid compound with a waxy texture.
Glycerin tripalmitate has a characteristic odor and is odorless.

Glycerin tripalmitate has a high melting point, typically around 63-65 degrees Celsius.
Glycerin tripalmitate is insoluble in water.
Glycerin tripalmitate is soluble in organic solvents such as ethanol, chloroform, and ether.

Glycerin tripalmitate appears as small crystals or flakes.
Glycerin tripalmitate is derived from the esterification of glycerol with three molecules of palmitic acid.
Glycerin tripalmitate is a triglyceride, belonging to the class of neutral lipids.
Glycerin tripalmitate formula of glycerin tripalmitate is C₅₃H₁₀₀O₆.

Glycerin tripalmitate is commonly found in natural fats and oils, particularly palm oil and animal fats.
Glycerin tripalmitate serves as an energy source in living organisms.
Glycerin tripalmitate is used in various industrial applications, including food, cosmetics, and pharmaceuticals.

Glycerin tripalmitate acts as an emulsifier, helping to blend oil and water-based ingredients.
Glycerin tripalmitate serves as a stabilizer, enhancing the consistency and shelf life of products.

Glycerin tripalmitate functions as a thickening agent, providing viscosity and texture to formulations.
Glycerin tripalmitate is utilized in the production of margarine, spreads, and baked goods, improving their texture and stability.
Glycerin tripalmitate is commonly found in skincare products, providing moisturizing and smoothing properties.
Glycerin tripalmitate contributes to the creamy texture and emollient effects of lotions, creams, and lip balms.

Glycerin tripalmitate is used in the formulation of solid dosage forms in the pharmaceutical industry.
Glycerin tripalmitate acts as a binder, helping to hold tablets together and maintain their integrity.

Glycerin tripalmitate, also known as glycerol tripalmitate or tripalmitin, is a chemical compound classified as a triglyceride.
Glycerin tripalmitate is an ester formed from the esterification of glycerol (glycerin) with three molecules of palmitic acid.
The chemical formula of glycerin tripalmitate is C₅₃H₁₀₀O₆.

Glycerin tripalmitate is a solid substance with a white or off-white color, and it has a melting point of approximately 63-65 degrees Celsius.
Glycerin tripalmitate is primarily found in natural fats and oils, such as palm oil and animal fats.
Glycerin tripalmitate is widely used in various industries, including food, cosmetics, pharmaceuticals, and research, due to its functional properties as an emulsifier, stabilizer, and thickening agent.



PROPERTIES


Chemical Formula: C₅₃H₁₀₀O₆
Molecular Weight: 853.43 g/mol
Physical State: Solid
Appearance: White or off-white solid
Odor: Odorless
Melting Point: Approximately 63-65 degrees Celsius
Boiling Point: Decomposes before boiling
Solubility: Insoluble in water
Solubility in Organic Solvents: Soluble in organic solvents such as ethanol, chloroform, and ether
Density: 0.942 g/cm³
Refractive Index: 1.433-1.437
Viscosity: 6.17 mPa·s at 20 degrees Celsius
Flash Point: >200 degrees Celsius (closed cup)
Autoignition Temperature: Approximately 400 degrees Celsius
pH Value: Not applicable (pH neutral)
Stability: Stable under normal conditions
Flammability: Not flammable
Explosion Limits: Not applicable (non-explosive)



FIRST AID


Inhalation:

If inhalation of the compound occurs, remove the affected person to fresh air immediately.
If respiratory symptoms develop, seek medical attention.
Provide artificial respiration if the person is not breathing, and administer oxygen if available.


Skin Contact:

In case of skin contact, promptly remove contaminated clothing and shoes.
Wash the affected area thoroughly with soap and water for at least 15 minutes.
Seek medical advice if irritation or any adverse effects persist.


Eye Contact:

If the compound comes into contact with the eyes, rinse them gently with lukewarm water for at least 15 minutes, ensuring to remove any contact lenses if present and easy to do so.
Seek immediate medical attention and continue rinsing the eyes during transport to the medical facility.


Ingestion:

If glycerin tripalmitate is ingested accidentally, do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water and give the affected person a small amount of water to drink if they are conscious and able to swallow.
Seek immediate medical attention and provide the medical staff with as much information as possible.



HANDLING AND STORAGE


Handling:

Personal Protection:
When handling glycerin tripalmitate, it is advisable to wear appropriate personal protective equipment (PPE) to minimize the risk of exposure.
This may include gloves, safety goggles or glasses, and protective clothing.

Ventilation:
Ensure that the handling area is well-ventilated to prevent the accumulation of vapors or dust.
Use local exhaust ventilation or mechanical ventilation if necessary.

Avoid Direct Contact:
Avoid direct contact with the compound.
If handling in powder form, minimize the generation of dust by using appropriate handling techniques, such as closed systems or dust collection equipment.

Good Hygiene Practices:
Practice good hygiene measures, such as washing hands thoroughly with soap and water after handling.
Avoid touching the face, eyes, or mouth with contaminated hands.

Avoid Incompatible Materials:
Keep glycerin tripalmitate away from strong oxidizing agents, strong acids, and alkalis, as they may react with or degrade the compound.

Static Electricity:
Take precautions to prevent the buildup of static electricity, as it may result in ignition or fire hazards.
Use grounding techniques and avoid frictional activities.


Storage:

Store in a Cool, Dry Place:
Store glycerin tripalmitate in a cool, dry place away from direct sunlight and sources of heat.
Maintain storage temperatures below 40 degrees Celsius.

Fire Protection:
Keep the compound away from potential ignition sources, such as open flames, sparks, and heat-generating equipment.
Follow appropriate fire protection measures in the storage area.

Chemical Compatibility:
Store glycerin tripalmitate separately from incompatible materials, such as strong oxidizing agents, strong acids, and alkalis, to prevent reactions or degradation.

Container Selection:
Store the compound in tightly sealed containers made of suitable materials, such as high-density polyethylene (HDPE) or stainless steel, to prevent leakage or contamination.

Labeling:
Ensure proper labeling of containers with the correct product name, hazards, and handling instructions.
This helps prevent confusion and ensures safe storage and handling.

Accessibility:
Store glycerin tripalmitate in a location that is only accessible to authorized personnel who are trained in its handling and aware of the associated hazards.

Spill and Leak Response:
Develop and implement procedures for spill and leak response, including containment measures and appropriate clean-up methods.
Dispose of waste material in accordance with local regulations.

Inventory Control:
Maintain proper inventory control to monitor storage conditions, expiration dates, and quantities of glycerin tripalmitate to minimize the risk of degradation or stock depletion.



SYNONYMS


Tripalmitin
Glyceryl Tripalmitate
Triglyceride Palmitin
Palmitic Acid Triglyceride
Glycerol Tripalmitate
Glycerol Palmitate
Glyceryl Palmitate Triester
Triglycerol Palmitate
Palmitoyl Glycerol
1,2,3-Tri-palmitoyl-glycerol
Glyceryl Tris(palmitate)
Triglyceride of Palmitic Acid
Palmitoyl Glycerin
1,2,3-Tri-palmitin
Glycerol Palmitate Triester
Glycerin Palmitate Triester
Tris(palmitoyl) Glycerol
Triglyceride C16
Tripalmitin Glyceride
Glycerin Palmitin
Glycerol Ester of Palmitic Acid
Palmitin
Palmitin Triglyceride
Glycerol Palmitic Acid Ester
Triglycerol Ester of Palmitic Acid
Palmitic Triglyceride
Tri-palmitoyl Glycerol
Palmitic Acid Glycerol Ester
Glyceryl Tripalmitate Palmitate
Glycerol Trihexadecanoate
Triglycerol Palmitate Ester
Glycerol Triester of Palmitic Acid
Glycerol Triglyceride Palmitate
Palmitoyl Glycerol Triester
Glycerol Tripalmitin
Tripalmitoyl Glycerol
Glyceryl Tri-palmitate
Triglycerol Palmitic Acid Ester
Glycerol Palmitic Acid Triester
Palmitoyl Glycerol Tri-palmitate
Glycerol Ester of Hexadecanoic Acid
Tri-palmitin Glyceride
Glycerol Esters of Palmitic Acid
Triglyceride Palmitate Ester
Glycerol 1,2,3-Tripalmitate
Palmitic Triglycerol
Tripalmitin Glyceride
Glycerol Tripalmitoyl Ester
Palmitic Acid Glycerol Triester
Glycerol Palmitic Triester
Tris(palmitoyl) Glycerol Ester
Glyceryl Palmitate Triglyceride
Triglyceride of Hexadecanoic Acid
Glycerol Tripalmitoylglycerol
Glycerin Tri-palmitoyl Ester
Palmitoyl Glycerol Palmitate
Triglyceride Palmitic Acid Triester
Glycerol Hexadecanoate Ester
Glycerol 1,2,3-Trihexadecanoate
Trihexadecanoyl Glycerol

SYNONYMS Glycerol; 1,2,3-Propanetriol; Glyceritol; Glycic Alcohol; 1,2,3-Trihydroxypropane; Trihydroxypropane; Clyzerin, Wasserfrei; Glyrol; Glysanin; Grocolene;CAS NO. 56-81-5

Glycerine; Glycerol; 1,2,3-Propanetriol; Glyceritol; Glycic Alcohol; 1,2,3-Trihydroxypropane; Trihydroxypropane; Clyzerin, Wasserfrei; Glyrol; Glysanin; Grocolene cas no: 56-81-5

Glycerine Monostearate Glycerine monostearate is composed of primary and auxiliary emulsifiers for a wide variety of personal care formulas. It is supplied as cream flakes. Glycerine monostearate is an emulsifier for a wide variety of personal care applications. Product: Cerasynt Stearates Industries: Personal Care Form: White to off-white flakes Use level: 0.25 - 3.0% Features & Benefits Nonionic auxiliary emulsifier Emulsion stabilizer Biodegradable 100% Natural Vegan suitable Impurities and other Glycerine monostearate risks According to a report in the International Journal of Toxicology by the cosmetic industry’s own Cosmetic Ingredient Review (CIR) committee, impurities found in various PEG compounds include ethylene oxide; 1,4-dioxane; polycyclic aromatic compounds; and heavy metals such as lead, iron, cobalt, nickel, cadmium, and arsenic. Many of these impurities are linked to cancer. PEG compounds often contain small amounts of ethylene oxide. Ethylene oxide (found in PEG-4, PEG-7, PEG4-dilaurate, and PEG 100) is highly toxic — even in small doses — and was used in World War I nerve gas. Exposure to ethylene glycol during its production, processing and clinical use has been linked to increased incidents of leukemia as well as several types of cancer. Finally, there is 1,4-dioxane (found in PEG-6, PEG-8, PEG-32, PEG-75, PEG-150, PEG-14M, and PEG-20M), which, on top of being a known carcinogen, may also combine with atmospheric oxygen to form explosive peroxides — not exactly something you want going on your skin. Even though responsible manufacturers do make efforts to remove these impurities (1,4-dioxane that can be removed from cosmetics through vacuum stripping during processing without an unreasonable increase in raw material cost), the cosmetic and personal care product industry has shown little interest in doing so. Surprisingly, PEG compounds are also used by natural cosmetics companies. Properties Chemical formula C21H42O4 Molar mass 358.563 g·mol−1 Appearance White solid Density 1.03 g/cm3 Melting point (Mix) 57–65 °C (135–149 °F) (1-) 81 °C (178 °F) [1] (2-) 73–74 °C (163–165 °F) Solubility in water Insoluble If you find Glycerine monostearate in your cosmetics… Although you might find conflicting information online regarding Polyethylene Glycol, PEGs family and their chemical relatives, it is something to pay attention to when choosing cosmetic and personal care products. If you have sensitive or damaged skin it might be a good idea to avoid products containing PEGs. Using CosmEthics app you can easy add PEGs to personal alerts. In our last blog post we wrote about vegan ingredients. Natural glycols are a good alternative to PEGs, for example natural vegetable glycerin can be used as both moisturiser and emulsifier. CosmEthics vegan list can help you find products that use vegetable glycerin as wetting agent. At present, there is not enough information shown on product labels to enable you to determine whether PEG compounds are contaminated. But if you must buy a product containing PEGs just make sure that your PEGs are coming from a respected brand. Glyceryl stearate and Glycerine monostearate is a combination of two emulsifying ingredients. The stabilising effect of both means that the product remains blended and will not separate. Description Glyceryl stearate is a solid and waxy compound. It is made by reacting glycerine (a soap by-product) with stearic acid (a naturally occurring, vegetable fatty acid). Glycerine monostearate is an off-white, solid ester of polyethylene glycol (a binder and a softener) and stearic acid. Applications Ideal for styling creams/lotions, conditioners, body care, facial care, sun care Related Applications Personal Care Cosmetics Hair Care Skin Care Sun Care Related Benefits Personal Care Natural Vegan Suitable Related Functions Personal Care Emulsifiers Glyceryl Stearate. Glycerine monostearate ester acts as an emulsion stabilizer and non-ionic auxiliary emulsifier. Glycerine monostearate ester is suggested for use in creams and lotions, conditioners and styling creams/lotions, body care, face and body washes, facial care, after-sun, self-tanning, and sunscreen applications. The Cerasynt esters range provides a variety of emulsifiers to meet formulation requirements. PROPERTIES Auxiliary emulsifiers. APPLICATIONS A wide variety of personal care formulas. Glycerine monostearate is a premium quality nonionic stabilizer and emulsifier. Manufactured using the highest quality raw materials for batch-to-batch reproducibility. What Is Glycerine monostearate? Glycerine monostearate and Glycerine monostearate SE are esterification products of glycerin and stearic acid. Glycerine monostearate is a white or cream-colored wax-like solid. Glycerine monostearate is a "Self-Emulsifying" form of Glycerine monostearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glycerine monostearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is Glycerine monostearate used in cosmetics and personal care products? Glycerine monostearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glycerine monostearate, and Glycerine monostearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Scientific Facts: Glycerine monostearate is made by reacting glycerin with stearic acid, a fatty acid obtained from animal and vegetable fats and oils. Glycerine monostearate SE is produced by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide yielding a product that contains Glycerine monostearate as well as potassium stearate and/or sodium stearate. What Is Glycerine monostearate Glycerine monostearate is esterification products of glycerin and stearic acid. Glycerine monostearate is a white or cream-colored wax-like solid. Glycerine monostearate SE is a "Self-Emulsifying" form of Glycerine monostearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glycerine monostearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is it used in cosmetics and personal care products? Glycerine monostearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glycerine monostearate, and Glycerine monostearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Glycerine monostearate is derived from palm kernel, vegetable or soy oil and is also found naturally in the human body. It acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It easily penetrates the skin and slows the loss of water from the skin by forming a barrier on the skin's surface. It has been shown to protect skin from free-radical damage as well. Functions of Glycerine monostearate Glycerine monostearate is derived from palm kernel, vegetable or soy oil and is also found naturally in the human body. It acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance (Source). It easily penetrates the skin and slows the loss of water from the skin by forming a barrier on the skin's surface. It has been shown to protect skin from free-radical damage as well. Chemically, Glycerine monostearate is used to stabilize products, decrease water evaporation, make products freeze-resistant, and keep them from forming surface crusts. Description: Glycerine monostearate SE (self-emulsifying as it contains a small amount 3-6% of potassium stearate) is the monoester of glycerin and stearic acid. Vegetable origin. It is an emulsifier with a HLB value of 5.8 and thus useful for making water-in-oil emulsions. It can also be used as a co-emulsifier and thickener for oil- in-water formulations. Off-white flakes, bland odor. Soluble in oil. CAS: 123-94-4 INCI Name: Glycerine monostearate Properties: Emulsifies water and oil phase, acts as stabilizer and thickener in o/w formulations, widely used in a variety of different cosmetic formulations. Use: Add to oil/emulsifier phase of formulas, melts at 55°C/130°F. Use level: 1-10%. For external use only. Applications: Moisturizing creams, lotions, ointments, antiperspirant, hair care and sunscreen. Glycerine monostearate (GMS) is one of the most commonly used ingredients in personal care formulations. But it's a material that is not well understood by most formulators. GMS (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. Glycerine monostearate, also known as Glycerine monostearate, or GMS, is EcoCert certified. Glycerine monostearate is the natural glyceryl ester from stearic acid (glycerin and stearic acid) which offers skin conditioning, moisturization and hydration due to the glycerin component. Functions as a non-ionic opacifier, thickener, and formulation stabilizer, where it also imparts a softer, smoother, feel to your emulsions. Glycerine monostearate is one of the best choices, for thickening and stabilizing, to use in combination with the lactylates, where it also functions as an emollient, and gives the emulsion more smoothness. Glycerine monostearate is the end result of reaction between glycerin and stearic acid. We all know what glycerin is and does (generally vegetable based humectant), and stearic acid is a fatty acid compound extracted from a variety of vegetable, animal, and oil sources such as palm kernel and soy. The end result of the reaction with glycerin and stearic acid is a cream-colored, waxy like substance. Details A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth. Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable. NAMELY Glycerol stearate is used as a non-ionic emulsifier or emollient in cosmetic products. It is widely used in moisturizers and is also found in hair care products for its antistatic properties. It can be derived from palm, olive or rapeseed oil... It is authorized in bio. Its functions (INCI) Emollient : Softens and softens the skin Emulsifying : Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil) This ingredient is present in 11.81% of cosmetics. Hand cream (46.51%) Moisturizing cream box (46.15%) Anti-aging night face cream (45.88%) Anti-aging hand cream (43.75%) Mascara (42.73%) Glycerine monostearate Glycerine monostearate is the natural glyceryl ester of glycerin and stearic acid. It offers excellent hydration and moisturization. It acts as a non-ionic opacifier, thickener, emollient and formulation stabilizer. It is used in skin care and body care applications. Glycerine monostearate is classified as : Emollient Emulsifying CAS Number 31566-31-1 EINECS/ELINCS No: 250-705-4 COSING REF No: 34103 INN Name: Glycerine monostearate PHARMACEUTICAL EUROPEAN NAME: glyceroli monostearas Chem/IUPAC Name: Glycerine monostearate Glycerine monostearate Learn all about Glycerine monostearate, including how it's made, and why Puracy uses Glycerine monostearate in our products. Derived from: coconut Pronunciation: (\ˈglis-rəl\ \stē-ə-ˌrāt\) Type: Naturally-derived Other names: monostearate What Is Glycerine monostearate? Glycerine monostearate, also called Glycerine monostearate, is a white or pale yellow waxy substance derived from palm kernel, olives, or coconuts. What Does Glycerine monostearate Do in Our products? Glycerine monostearate is an emollient that keeps products blended together; it can also be a surfactant, emulsifier, and thickener in food — often it’s used as a dough conditioner and to keep things from going stale.[1] In our products, however, Glycerine monostearate is used for its most common purpose — to bind moisture to the skin. For this reason, it is a common ingredient in thousands of cosmetic products, including lotions, makeup, skin cleansers, and other items. Why Puracy Uses Glycerine monostearate We use Glycerine monostearate in several of our products as a moisturizer; it also forms a barrier on the skin and prevents products from feeling greasy. As an emulsifier, it also allows products to stay blended.[5] Several studies and clinical tests find that Glycerine monostearate causes little or no skin or eye irritation and is not a danger in formulations that might be inhaled.[6,7,8] In addition, a number of clinical trials have found that Glycerine monostearate in moisturizers can lessen symptoms and signs of atopic dermatitis, including pruritus, erythema, fissuring, and lichenification.[9] In 1982 and again in 2015, the Cosmetic Ingredient Review deemed the ingredient safe for use in cosmetics.[10] Whole Foods has deemed the ingredient acceptable in its body care quality standards.[11] How Glycerine monostearate Is Made Glycerine monostearate is formed through a reaction of glycerin with stearic acid, which is a fatty acid that comes from animal and vegetable fats and oils. Glycerine monostearate SE, the self-emulsifying form of the substance, is made by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide. That produces a substance that contains Glycerine monostearate, potassium stearate, and/or sodium stearate Glycerine monostearate (GMS) is one of the most commonly used ingredients in personal care formulations. But it’s a material that is not well understood by most formulators. GMS (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. LGN-based emulsions containing thickening polymers are the most common type of oil-in-water formulations sold globally. Most GMS used in personal care products should actually be called glyceryl distearate (EU), since many common grades only contain around 40% alpha monostearate (EU), 5% glyceryl tristearate (EU), and 50% glyceryl distearate. There are also grades commercially available that contain 30%, 60%, and 90% GMS. The 90% alpha mono grades can only be produced by molecular distillation and are widely used in the food industry. Functionally, there is a big difference in performance if you use a 90% versus 40% mono. A 90% mono has a higher melting point (69°C versus 58-63°C), lighter skin feel, and a higher HLB (EU) (~4-5, versus ~3). The higher HLB of the 90% mono enables you to form LGNs much easier with lower emulsifier levels and energy than when using cetyl (EU)/stearyl alcohol (EU). There are also self-emulsifying (SE) grades of GMS available, which are typically combined with PEG 100 stearate (EU), potassium stearate (EU), or sodium lauryl sulfate (EU). Glycerine monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.[3] It takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic. Chemically it is the glycerol ester of stearic acid. Structure, synthesis, and occurrence Glycerine monostearate exists as three stereoisomers, the enantiomeric pair of 1-Glycerine monostearate and 2-Glycerine monostearate. Typically these are encountered as a mixture as many of their properties are similar. Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol. Glycerine monostearate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase. It is present at very low levels in certain seed oils. Uses Glycerine monostearate is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant. It is also used in cosmetics and hair-care products.[5] Glycerine monostearate is largely used in baking preparations to add "body" to the food. It is somewhat responsible for giving ice cream and whipped cream their smooth texture. It is sometimes used as an antistaling agent in bread. What Is It? Glycerine monostearate and Glyceryl Stearate SE are esterification products of glycerin and stearic acid. Glycerine monostearate is a white or cream-colored wax-like solid. Glycerine monostearate SE is a "Self-Emulsifying" form of Glycerine monostearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glycerine monostearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is it used in cosmetics and personal care products? Glycerine monostearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glycerine monostearate, and Glycerine monostearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Scientific Facts: Glycerine monostearate is made by reacting glycerin with stearic acid, a fatty acid obtained from animal and vegetable fats and oils. Glyceryl Stearate SE is produced by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide yielding a product that contains Glycerine monostearate as well as potassium stearate and/or sodium stearate. Glycerine monostearate is the natural glyceryl ester of glycerin and stearic acid. It offers excellent hydration and moisturization. It acts as a non-ionic opacifier, thickener, emollient and formulation stabilizer. It is used in skin care and body care applications. Glycerine monostearate is classified as : Emollient Emulsifying Learn all about Glycerine monostearate, including how it's made, and why Puracy uses Glycerine monostearate in our products. Derived from: coconut Pronunciation: (\ˈglis-rəl\ \stē-ə-ˌrāt\) Type: Naturally-derived Other names: monostearate What Is Glycerine monostearate? Glycerine monostearate, also called Glycerine monostearate, is a white or pale yellow waxy substance derived from palm kernel, olives, or coconuts. What Does Glycerine monostearate Do in Our products? Glycerine monostearate is an emollient that keeps products blended together; it can also be a surfactant, emulsifier, and thickener in food — often it’s used as a dough conditioner and to keep things from going stale.[1] In our products, however, Glycerine monostearate is used for its most common purpose — to bind moisture to the skin. For this reason, it is a common ingredient in thousands of cosmetic products, including lotions, makeup, skin cleansers, and other items.[2,3] Why Puracy Uses Glycerine monostearate We use Glycerine monostearate in several of our products as a moisturizer; it also forms a barrier on the skin and prevents products from feeling greasy. As an emulsifier, it also allows products to stay blended.[5] Several studies and clinical tests find that Glycerine monostearate causes little or no skin or eye irritation and is not a danger in formulations that might be inhaled.[6,7,8] In addition, a number of clinical trials have found that Glycerine monostearate in moisturizers can lessen symptoms and signs of atopic dermatitis, including pruritus, erythema, fissuring, and lichenification.[9] In 1982 and again in 2015, the Cosmetic Ingredient Review deemed the ingredient safe for use in cosmetics.[10] Whole Foods has deemed the ingredient acceptable in its body care quality standards. How Glycerine monostearate Is Made Glycerine monostearate is formed through a reaction of glycerin with stearic acid, which is a fatty acid that comes from animal and vegetable fats and oils. Glycerine monostearate SE, the self-emulsifying form of the substance, is made by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide. That produces a substance that contains Glycerine monostearate, potassium stearate, and/or sodium stearate. Glyceryl stearate (Glycerine monostearate) is one of the most commonly used ingredients in personal care formulations. But it’s a material that is not well understood by most formulators. Glycerine monostearate (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. LGN-based emulsions containing thickening polymers are the most common type of oil-in-water formulations sold globally. Most Glycerine monostearate used in personal care products should actually be called glyceryl distearate (EU), since many common grades only contain around 40% alpha monostearate (EU), 5% glyceryl tristearate (EU), and 50% glyceryl distearate. There are also grades commercially available that contain 30%, 60%, and 90% Glycerine monostearate. The 90% alpha mono grades can only be produced by molecular distillation and are widely used in the food industry. Functionally, there is a big difference in performance if you use a 90% versus 40% mono. A 90% mono has a higher melting point (69°C versus 58-63°C), lighter skin feel, and a higher HLB (EU) (~4-5, versus ~3). The higher HLB of the 90% mono enables you to form LGNs much easier with lower emulsifier levels and energy than when using cetyl (EU)/stearyl alcohol (EU). There are also self-emulsifying (SE) grades of Glycerine monostearate available, which are typically combined with PEG 100 stearate (EU), potassium stearate (EU), or sodium lauryl sulfate (EU). Glycerine monostearate Glycerine monostearate is created by the esterification of glycerin and stearic acid. Glycerine monostearate creates an excellent emulsion and when used in combination with other emulsifiers, creates a stable lotion. Characteristics An interesting characteristic of Glycerine monostearate is the ability to make the oils which are combined in the emulsion non greasy, so for example Sunflower can be combined, without adding greasiness to the final product, allowing creams and lotions to be produced which carry the properties of the oil without the greasiness. Glycerine monostearate can be used to pearlise shower gel, shampoo and hand wash if added in combination with glycerine. How to use Heat the Glycerine monostearate to 60c - 70c within the oil stage of your formulations. Ensure the Glycerine monostearate is fully dissolved into your oil stage (use agitation if required) in order to minimise the risk of graininess in your final formulation. Precautions At pure usage levels it can cause irritation to the skin. When blending always take the following precautions: Use gloves (disposable are ideal) Take care when handling hot oils Wear eye protection Work in a well ventilated room Keep ingredients and hot oils away from children If ingested, seek immediate medical advice If contact made with eyes, rinse immediately with clean warm water and seek medical advice if in any doubt. Safety First In addition to our precautions and general safety information, we always recommend keeping a first aid kit nearby. You are working with hot water and oils, accidents can happen, so always be prepared! Is Glycerine monostearate Safe? Toxicity The safety of PEG compounds has been called into question in recent years. The questioning of the safety of this ingredient is due to toxicity concerns that result from impurities found in PEG compounds. The impurities of concern are ethylene oxide and 1,4 dioxane, both are by-products of the manufacturing process. Both 1,4 dioxane and ethylene oxide have been suggested to be linked with breast and uterine cancers. While these impurities may have been a concern previously, ingredient manufacturers and improved processes have eliminated the risk of impurities in the final product. The level of impurities that were found initially in PEG manufacturing was low in comparison to the levels proposed to be linked to cancers. Longitudinal studies or studies over a long period of use of PEG compounds have not found any significant toxicity or any significant impact on reproductive health. When applied topically, Glycerine monostearate is not believed to pose significant dangers to human health. It doesn’t penetrate deeply into the skin and isn’t thought to have bioaccumulation concerns when used topically. Irritation Through research, PEG compounds have exhibited evidence that they are non-irritating ingredients to the eyes or the skin. This research used highly concentrated forms of the ingredient, concentrations that would not be found in your skincare products. The Cosmetic Ingredient Review Expert Panel found PEG compounds to be non-photosensitizing and non-irritating at concentrations up to 100%. However, despite the evidence suggesting that PEG compounds are non-irritating, some research has indicated that irritation can occur when the skin is broken or already irritated. In a study that was trialing the use of PEG containing antimicrobial cream on burn patients, some patients experienced kidney toxicity. The concentration of PEG compounds was identified to be the culprit. Given that there was no evidence of toxicity in any study of PEGs and intact skin, the Cosmetic Ingredient Review Expert Panel amended their safety guidelines to exclude the use of PEG containing products on broken or damaged skin. Is Glycerine monostearate Vegan? Depending on the source of the stearic acid used to make Glycerine monostearate, it may be vegan. Most of the time, stearic acid is derived from plants. However, it can also be derived from animal origin. If it is of animal origin, the product has to comply with animal by-product regulation. Check with the brand you are thinking of using to determine whether their Glycerine monostearate is derived from a plant or animal source. Why Is Glycerine monostearate Used? Emulsifier Glycerine monostearate is included in skincare and beauty products for a variety of reasons, ranging from making the skin softer to helping product formulations better keep their original consistency. As an emollient, Glycerine monostearate is included within skincare product formulations to give the skin a softer feel. It achieves this through strengthening the skin’s moisture barrier by forming a thin fatty layer on the skin’s surface, which prevents moisture loss and increases overall hydration. This moisturizing effect increases the hydration of skin cells, which in turn makes the skin softer and boosts skin health. Texture Another use for Glycerine monostearate has to do with its emulsification properties. Emulsifiers are valued in the skincare and personal care industries because of their ability to mix water and oils. Without this ability, the oils in many formulations would begin to separate from the water molecules, thus undermining product texture and consistency. Glycerine monostearate is also used to help to cleanse through mixing oil and dirt so that it can be rinsed away. Surfactant Lastly, Glycerine monostearate can also act as a surfactant, when used in body and facial cleansers. Surfactants disrupt surface tension, helping to mix water and oil. This characteristic helps the ingredient cleanse the skin by mixing oil with water, lifting dirt trapped inside the skin’s oils, and rinsing it away from the skin. What Types of Products Contain Glycerine monostearate? There are many products in the skin and personal care industry that are formulated with Glycerine monostearate because of its benefits to formulations and its relative safety. Facial cleansers, shampoos, lotions, and face creams have all been known to contain this ingredient. If you’ve had problems with this ingredient before, or if your doctor has advised you to stay away from Glycerine monostearate, it’s vital to read ingredient labels for any personal care product as it has many applications. What are PEGs? You have probably noticed that many of cosmetics and personal care products you use have different types of PEGs among ingredients. PEG, which is the abbreviation of polyethylene glycol, is not a definitive chemical entity in itself, but rather a mixture of compounds, of polymers that have been bonded together. Polyethylene is the most common form of plastic, and when combined with glycol, it becomes a thick and sticky liquid. PEGs are almost often followed by a number, for example PEG-6, PEG-8, PEG 100 and so on. This number represents the approximate molecular weight of that compound. Typically, cosmetics use PEGs with smaller molecular weights. The lower the molecular weight, the easier it is for the compound to penetrate the skin. Often, PEGs are connected to another molecule. You might see, for example, Glycerine monostearate as an ingredient. This means that the polyethylene glycol polymer with an approximate molecular weight of 100 is attached chemically to stearic acid. In cosmetics, PEGs function in three ways: as emollients (which help soften and lubricate the skin), as emulsifiers (which help water-based and oil-based ingredients mix properly), and as vehicles that help deliver other ingredients deeper into the skin. What effect do Glycerine monostearate have on your skin? Polyethylene glycol compounds have not received a lot of attention from consumer groups but they should. The most important thing to know about PEGs is that they have a penetration enhancing effect, the magnitude of which is dependent upon a variety of variables. These include: both the structure and molecular weight of the PEG, other chemical constituents in the formula, and, most importantly, the overall health of the skin. PEGs of all sizes may penetrate through injured skin with compromised barrier function. So it is very important to avoid products with PEGs if your skin is not in best condition. Skin penetration enhancing effects have been shown with PEG-2 and PEG-9 stearate. This penetration enhancing effect is important for three reasons: 1) If your skin care product contains a bunch of other undesirable ingredients, PEGs will make it easier for them to get down deep into your skin. 2) By altering the surface tension of the skin, PEGs may upset the natural moisture balance. 3) Glycerine monostearate are not always pure, but often come contaminated with a host of toxic impurities. Emulsifiers Emulsifiers are used to aid the incorporation and stabilization of air bubbles in the batter, especially in the presence of fats or oils. The most commonly used emulsifiers for this purpose are glycerol monostearate (Glycerine monostearate) and polyglycerol esters, with the former being the more effective of the two on a weight-for-weight basis. Both emulsifiers are commonly used in a paste form, i.e., dispersed in water with other ingredients which promote gel stability. Emulsifiers like Glycerine monostearate may exist in a number of forms when dispersed in water and it is important it is in the active alpha-gel form when used for cake making. Without Glycerine monostearate the egg protein will largely stabilize the air bubbles and the sponge will have a reasonable volume, but often with an area of coarse open-cell structure in the crumb. The addition of a small level of Glycerine monostearate somewhat unexpe

GLYCEROL FORMAL N° CAS : 4740-78-7 Nom INCI : GLYCEROL FORMAL Nom chimique : 1,3-Dioxolane-4-methanol N° EINECS/ELINCS : 225-248-9 Ses fonctions (INCI) Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes. α,α'-Glycerol formal ?,α'glycerol formal 1,3-Dioxan-5-ol [ACD/Index Name] [ACD/IUPAC Name] 1,3-Dioxan-5-ol [German] [ACD/Index Name] [ACD/IUPAC Name] 1,3-Dioxan-5-ol [French] [ACD/Index Name] [ACD/IUPAC Name] 1,3-Formalglycerol 225-248-9 [EINECS] 4740-78-7 [RN] 5-m-Dioxanol a,a'-Formaldehyde Glycerol a,a'-Methylene Glycerin Glycerol Formal GLYCEROL FORMAL, α,α' "1,3-DIOXAN-5-OL" [1,3]Dioxan-5-ol 1,3-dioxan-5-ol 98% 5-Hydroxy-1,3-dioxane 5-Hydroxy-m-dioxane C4H8O3 [Formula] EINECS 225-248-9 glycerol formal (=1,3-dioxan-5-ol) glycerol formal, 99+%, mixture of isomers, stabilized Glycerol formal, α,α' GLYCEROL-A,β-FORMAL m-Dioxan-5-ol MFCD00003218 [MDL number] MFCD00014645 [MDL number] MFCD10039829 ST5409435 UNII-3L7GR2604E

SYNONYMS Glyceryl monostearate; 3-Stearoyloxy-1,2-propanediol; Glyceryl stearate; Alpha-Monostearin; Monostearin; Octadecanoic acid, 2,3-dihydroxypropyl ester; Glycerin 1-monostearate; Glycerin 1-stearate; Glycerol alpha-monostearate; Glyceryl 1-monostearate; Stearic acid alpha-monoglyceride; Stearic acid 1-monoglyceride; 1-Glyceryl stearate; 1-Monostearin; 1-Monostearoylglycerol; 1,2,3-Propanetriol 1-octadecanoyl ester;CAS NO. 123-94-4,

Glycerol monolaurate (GML) is a broadly antimicrobial fatty acid monoester, killing bacteria, fungi, and enveloped viruses.
Glycerol monolaurate (GML) is an organic compound that belongs to the class of monoglycerides, specifically a monoglyceride ester.
Glycerol monolaurate (GML) is a fatty acid monoglyceride, which richly exists in coconut oil, palm oil, and human milk.

CAS Number: 27215-38-9
Molecular Formula: C15H30O4
Molecular Weight: 274.4
EINECS Number: 248-337-4

Glycerol monolaurate (GML) is composed of glycerol (also known as glycerin) and lauric acid.
Glycerol monolaurate (GML) is a saturated fatty acid commonly found in coconut oil and palm kernel oil.
Glycerol monolaurate (GML) is a 1-monoglyceride with dodecanoyl (lauroyl) as the acyl group.

Glycerol monolaurate (GML) (abbreviated GML; also called Monolaurin, glyceryl laurate, and 1-lauroyl-glycerol) is a monoglyceride.
Glycerol monolaurate (GML) is the mono-ester formed from glycerol and lauric acid.
Glycerol monolaurate (GML) is chemical formula is C15H30O4.

Glycerol monolaurate (GML) is found in coconut oil and may be similar to other monoglycerides found in human breast milk.
Glycerol monolaurate (GML) can be ingested in coconut oil and the human body converts it into monolaurin.
Furthermore, coconut oil, coconut cream, grated coconut and others products are sources of lauric acid and, consequently, monolaurin.

Glycerol monolaurate (GML) is a naturally occurring fatty acid widely utilized in food, cosmetics, and homeopathic supplements.
Glycerol monolaurate (GML) is a potent antimicrobial agent that targets a range of bacteria, fungi, and enveloped viruses but select findings suggest that Glycerol monolaurate (GML) also has immunomodulatory functions.
Glycerol monolaurate (GML) is a naturally occurring fatty acid which is commonly used in food, cosmetics, and homoeopathic supplements.

Glycerol monolaurate (GML) is considered as an effective antibacterial drug that kills a variety of bacteria, fungi, and enveloped viruses.
This offering is a naturally occurring fatty acid molecule and antibacterial agent which acts as an ingredient in several goods, including deodorants, lotions, and cosmetics.
Glycerol monolaurate (GML) GML is highly effective food preservative and emulsifier.

The said product is also widely accessible as a homoeopathic supplement.
Glycerol monolaurate (GML) is a naturally occurring surfactant that has potential use as an additive to tampons and wound dressings to reduce the incidence of certain bacterial toxin-mediated illnesses.
Glycerol monolaurate (GML) emulsifier for sale is a versatile ingredient that has many applications in the food industry.

Glycerol monolaurate (GML) can be used as an emulsifier, antimicrobial, texture enhancer, flavor enhancer, and clean-label ingredient and is found in a wide range of products, including baked goods, dairy products, and beverages.
Glycerol monolaurate (GML)'s versatility makes it an ideal ingredient for many different types of foods, and its natural properties make it a safe and healthy choice.
Glycerol monolaurate (GML) is an advanced food emulsifiers preservatives nowadays, exists in breast milk naturally ,and it is recognized as a fine food emulsifier internationally.

Glycerol monolaurate (GML) is a safe, effective, broad-spectrum antibacterial agent.
Glycerol monolaurate (GML) is LD50> 10g/kg, is a non-toxic food additive.
In April 2005, Chinese Ministry of Health approved that GML can be used in all kinds of food, and no dosage limit, it can be added according to actual needs.

The biggest advantage of Glycerol monolaurate (GML) is the "not preservatives, but more than preservative".
Glycerol monolaurate (GML) is bacteriostatic effect will not change with the change of pH value supose pH value is within the scope of 4 ~ 8.
Glycerol monolaurate (GML) is antibacterial spectrum was wide, it has strong interaction in the common bacteria, fungi, yeast in food, and also can inhibit variety of viruses and protozoa.

Glycerol monolaurate (GML) is an antimicrobial agent that has potent activity against gram-positive bacteria.
This study examines GML antibacterial activity in comparison to lauric acid, in broth cultures compared to biofilm cultures, and against a wide range of gram-positive, gram-negative, and non-gram staining bacteria.
Glycerol monolaurate (GML) 90% min is an advanced food emulsifiers preservatives nowadays, exists in breast milk naturally .

Glycerol monolaurate (GML) it is recognized as a fine food emulsifier internationally.
Glycerol monolaurate (GML) is a safe, effective, broad-spectrum antibacterial agent.
In April 2005, Chinese Ministry of Health approved that GML can be used in all kinds of food, and no dosage limit, it can be added according to actual needs.

Glycerol monolaurate (GML) (GB15612-95 (GML-90)) is in the form of milky white beads or powder.
Glycerol monolaurate (GML) has a monoglyceride content of 90-95%.
Glycerol monolaurate (GML) can be used to prevent dough from aging, provide foaming stability, and improve texture, stability, and taste.

Glycerol monolaurate (GML) can be used in breads, flour products, peanut butter, and beverages.
Glycerol monolaurate (GML) Glycerol Laurate E471 (GML) CAS No.:142-18-7 is not merely an excellent emulsifier,but also a safe and efficient antibacterial agent with wide spectrum and it is also not limited by pH value.
In the condition of neutral or slightly alkaline conditions,it still has a good antibacterial effect.

Glycerol monolaurate (GML) is a compound that has gained significant attention in recent years.
As more and more people are following gluten-free diets, there is a growing concern whether or not GML is gluten-free.
In this article, will delve into the world of Glycerol monolaurate (GML) and gluten, exploring the chemical composition of Glycerol monolaurate (GML), its common uses, the concept of gluten-free, and the connection between GML and gluten.

Glycerol monolaurate (GML), also known as dodecanoic acid monoglyceride, is an esterophilic nonionic surfactant that is naturally found in breast milk, coconut oil, and American sylvestris.
The food emulsifier has an HLB value of 5.2 and is a safe, efficient and broad-spectrum bacteriostatic agent with dual functions of emulsifying and antiseptic.
Glycerol monolaurate (GML) is used as a surfactant, preservative and emulsifier in food, besides it can be used in cosmetics and medicines.

This study obtained to optimize Glycerol monolaurate (GML) synthesis from glycerol and lauric acid. It consisted of two steps, dealumination of zeolite Y catalyst and optimization of GML synthesis.
Glycerol monolaurate (GML), is glyceryl laurate or 1-lauroyl-glycerol, is a monoglyceride.
Glycerol monolaurate (GML) is shortly termed as GML.

Glycerol monolaurate (GML) is the mono-ester derived from glycerol and lauric acid.
Glycerol monolaurate (GML) is also widely known as monolaurin.
Chemical formula of Glycerol monolaurate (GML) is C15H30O4.

Glycerol monolaurate (GML) is a naturally occurring fatty acid that has wide range of application in food, cosmetics, personal care and homeopathic supplements.
Glycerol monolaurate (GML) is a broadspectrum antimicrobial agent that has effective reaction against the grampositive bacteria and targets a variety of bacteria, fungi, and enveloped viruses.
Glycerol monolaurate (GML) is a type of lipophilicity nonionic surfactant, which naturally exists in breast milk and palmetto, a type of palm tree.

Glycerol monolaurate (GML) well-known as a good food emulsifier and also a safe and efficient antibacterial agent.
Glycerol monolaurate (GML) has a glycerol molecule attached to a single lauric acid molecule through an ester linkage.
Glycerol monolaurate (GML) is typically a white to light yellowish solid or a waxy substance.

Glycerol monolaurate (GML) is soluble in fats and oils but has limited solubility in water.
Glycerol monolaurate (GML) is known for its antimicrobial properties. It exhibits inhibitory effects against various microorganisms, including bacteria, viruses, and fungi.
This makes it useful in applications where microbial contamination needs to be controlled.

Glycerol monolaurate (GML) is commonly used as an emulsifier and stabilizer in the food and cosmetic industries.
Glycerol monolaurate (GML) helps improve the texture and shelf life of certain products by preventing the separation of water and oil phases.
Due to its antimicrobial properties, Glycerol monolaurate (GML) is utilized in food preservation to inhibit the growth of bacteria and extend the shelf life of certain food products, especially those prone to microbial spoilage.

Glycerol monolaurate (GML) is found in various personal care products, such as creams, lotions, and cosmetics, where it serves as an emulsifier and stabilizing agent.
Glycerol monolaurate (GML) has been studied for its potential applications in medicine.
Glycerol monolaurate (GML) has shown promise in inhibiting the growth of certain pathogenic bacteria and viruses, making it a subject of interest in the development of antimicrobial agents.

Glycerol monolaurate (GML) is available as a dietary supplement and is sometimes marketed for its potential health benefits, including immune system support.
Glycerol monolaurate (GML) is a broadly antimicrobial fatty acid monoester, killing bacteria, fungi, and enveloped viruses.
Glycerol monolaurate (GML) is a 1-monoglyceride and a dodecanoate ester.

Melting point: 50 °C
storage temp.: −20°C
LogP: 4.029 (est)
FDA UNII: Y98611C087

Glycerol monolaurate (GML) is a kind of broad antibiotic, which is safe, efficient and extensive.
Glycerol monolaurate (GML) can inhibit some kinds of virus and a lot of bacteria and bioplasm.
Glycerol monolaurate (GML) is better than pentadiene carboxylic acid, benzene carboxylic acid and P-hydroxy benzoic acid ester.

Glycerol monolaurate (GML) is insoluble in water and has emulsifying and lubricating properties.
Widely used in food, cosmetics, textiles, leather, and other industries.
Glycerol monolaurate (GML) antiviral mechanism is that lauric acid can cause viral membrane protein leakage, monolaurate can be inserted into the membrane of the virus, both of which lead to reduced or loss of replication.

Glycerol monolaurate (GML) is commonly said that monoglyceride destroys the membrane structure of the virus and inhibits its ability to replicate, that is, it leaves the virus in a half-dead resting state, in which the non-replicating virus acts as an antigen and stimulates the production of corresponding antibodies in animals.
Several studies have illustrated that GML is ≥ 200 times more effective in bactericidal activities or several chemical reactions than lauric acid.

Some cliquey reports and findings have illuminated that Glycerol monolaurate (GML) also has immunomodulatory functions.
A few detailed researches have shed light on an astonishing research which reveals that the widely used anti-microbial agent Glycerol monolaurate (GML) also alters the lipid dynamics of human T cells, leading to their defective signaling and function.
Glycerol monolaurate (GML) is chemical having potent antimicrobial properties and so has a wide range of applications pharmaceutical or healthcare sectors for medical and sterilizing purposes.

Along with this, Glycerol monolaurate (GML) is a well-known food emulsifier thus, witnessing demand of product from food or dietary sectors.
In recent years, Glycerol monolaurate (GML) is also being majorly used to make a number of cosmetics and beauty care products, due to its antibacterial, antifungal, etc. properties.
Glycerol monolaurate (GML) is a fascinating compound that occurs naturally in coconuts and breast milk.

Glycerol monolaurate (GML) is a monoester of lauric acid and glycerol, which gives it unique properties and makes it highly versatile in various industries.
Glycerol monolaurate (GML) is composed of a glycerol molecule esterified with a single lauric acid molecule.
This means that GML consists of one Glycerol monolaurate (GML) and one lauric acid molecule bonded together.

This unique molecular structure is what gives Glycerol monolaurate (GML) its distinct properties and makes it an excellent emulsifier and preservative.
Glycerol monolaurate (GML) is used as an emulsifier, it helps blend oil and water-based ingredients together, creating a smooth and stable mixture.
This property is highly valued in the food and cosmetic industries, where Glycerol monolaurate (GML) is extensively used to improve the texture and stability of various products.

Glycerol monolaurate (GML)'s antimicrobial properties make it an effective preservative.
Glycerol monolaurate (GML) has the ability to inhibit the growth of certain bacteria and fungi, making it an ideal choice for extending the shelf life of food and cosmetic products.
Glycerol monolaurate (GML) interacts with lipids, and its antimicrobial properties are attributed to its ability to disrupt the lipid bilayers of microbial cell membranes.

This disruption can lead to the inhibition of microbial growth.
Glycerol monolaurate (GML) acts as a stabilizing agent in certain food products, preventing the separation of oil and water phases.
This property is particularly useful in emulsified products like salad dressings and mayonnaise.

Glycerol monolaurate (GML), is naturally found in coconut oil and palm kernel oil.
Glycerol monolaurate (GML) derived from these sources is sometimes preferred for products marketed as natural or organic.
Glycerol monolaurate (GML) may have antiviral properties, making it a subject of interest in the development of interventions against certain viruses.

Glycerol monolaurate (GML) has been studied in the context of viral infections, including those caused by enveloped viruses.
Some studies have explored the anti-inflammatory effects of Glycerol monolaurate (GML).
Glycerol monolaurate (GML) may modulate immune responses and inflammatory processes, making it potentially relevant in conditions associated with inflammation.

Glycerol monolaurate (GML) is employed as a preservative in certain food products, helping to inhibit the growth of spoilage microorganisms and extending the product's shelf life.
Due to its emulsifying and stabilizing properties, Glycerol monolaurate (GML) is utilized in skin care products. It may contribute to the overall texture and stability of creams and lotions.
Glycerol monolaurate (GML) can be compatible with other food additives, such as antioxidants and preservatives, enhancing its effectiveness in food preservation.

Some studies have explored Glycerol monolaurate (GML)'s potential in modulating the immune system, making it an area of interest in immunology research.
The regulatory status of Glycerol monolaurate (GML) varies by region, and it is important for manufacturers to comply with local regulations and safety standards when using Glycerol monolaurate (GML) in food, cosmetics, or other products.
Glycerol monolaurate (GML) has demonstrated antifungal properties in some studies.

This makes it relevant in inhibiting the growth of certain fungi, extending its potential applications to products where fungal contamination is a concern.
Glycerol monolaurate (GML) is sometimes incorporated into animal feed as an antimicrobial agent to help control microbial growth and improve feed hygiene.
Glycerol monolaurate (GML) is effective in stabilizing water-in-oil emulsions, a property that finds application in various food and cosmetic formulations.

In some applications, Glycerol monolaurate (GML) may exhibit synergistic effects when combined with other antimicrobial agents.
This can enhance its overall effectiveness in inhibiting microbial growth.
Some research suggests that Glycerol monolaurate (GML) may influence biofilm formation, a consideration in environments where microbial biofilms can lead to contamination or product spoilage.

Glycerol monolaurate (GML) is generally considered biodegradable, contributing to its environmentally friendly profile compared to some synthetic additives.
Glycerol monolaurate (GML)'s surfactant properties make it suitable for use in certain detergent formulations, contributing to emulsification and stabilization.
In addition to its use in cosmetics, Glycerol monolaurate (GML) may be found in topical formulations for its potential antimicrobial and anti-inflammatory effects on the skin.

Glycerol monolaurate (GML) has been explored in encapsulation technologies, where it can be used to encapsulate and deliver bioactive compounds in a controlled manner.
Glycerol monolaurate (GML) is effective against a broad spectrum of microorganisms, it's essential to be aware that some microorganisms may develop resistance over time, highlighting the importance of responsible and judicious use.
Some studies have investigated the impact of Glycerol monolaurate (GML) on gut health.

Glycerol monolaurate (GML) may influence the gut microbiota and potentially offer benefits in maintaining a balanced microbial environment.
Ongoing research explores the therapeutic potential of Glycerol monolaurate (GML) in various health conditions, including its antimicrobial, anti-inflammatory, and immunomodulatory properties.

Uses:
Glycerol monolaurate (GML) is a monoglyceride emulsifier produced by the esterification of glycerin and lauric acid.
Glycerol monolaurate (GML) has a melting point of 56°c, a maximum iodine value of 0.5, and a saponification value of 200–206.
In a highly purified form, it shows antimicrobial properties against microorganisms with the exception of gram-negative organisms.

Glycerol monolaurate (GML) is effective against gram-negative organisms when formulated with bha or edta.
Glycerol monolaurate (GML) is used in baked goods, whipped toppings, frosting, glazes, and cheese products.
Glycerol monolaurate (GML) is most commonly used as a surfactant in cosmetics, such as deodorants.

As a food additive Glycerol monolaurate (GML) is also used as an emulsifier or preservative.
Glycerol monolaurate (GML) is also marketed as a dietary supplement.
Glycerol monolaurate (GML) exists in breast milk, having the ability of resist pathogenic microbe inflection, extensively be applied in the infant milk powder, rice flour etc.

Glycerol monolaurate (GML) is explored in the development of medical and health products due to its potential antimicrobial properties.
Glycerol monolaurate (GML) may find applications in wound care and other medical formulations.
Glycerol monolaurate (GML) has been studied for its impact on biofilm formation.

Glycerol monolaurate (GML) may serve as an anti-biofilm agent, which is important in preventing the formation of bacterial biofilms in various settings.
Some research suggests that GML exhibits anti-inflammatory effects.
This property may be relevant in formulations aimed at addressing inflammatory conditions.

Glycerol monolaurate (GML)'s antimicrobial properties make it a potential ingredient in oral care products, such as toothpaste and mouthwash, for its role in inhibiting the growth of oral bacteria.
Glycerol monolaurate (GML) is investigated for its biomedical applications, including its use in biomaterials and coatings to prevent microbial contamination and biofilm formation on medical devices.

In food packaging materials, Glycerol monolaurate (GML) may be incorporated to provide antimicrobial protection, helping to prevent the growth of spoilage microorganisms and enhance the safety of packaged food.
Glycerol monolaurate (GML), as a dietary supplement, may be considered for its potential role in supporting the immune system and overall health.
Glycerol monolaurate (GML) is sometimes included in formulations aimed at dietary management.

In the oil and gas industry, Glycerol monolaurate (GML) may be explored for its antimicrobial properties to control microbial growth in various processes and equipment.
Glycerol monolaurate (GML)'s properties may be harnessed in anti-corrosion formulations to inhibit microbial-induced corrosion in certain industrial settings.
Glycerol monolaurate (GML) is used in the beverage industry to prevent microbial contamination and enhance the shelf life of beverages, such as juices and sports drinks.

Glycerol monolaurate (GML) may be incorporated into pet care products, such as shampoos and grooming items, for its emulsifying and stabilizing properties.
In agriculture, Glycerol monolaurate (GML) may be explored for its potential role in plant protection, controlling microbial growth in certain agricultural formulations.
Glycerol monolaurate (GML)'s biodegradable nature may be considered in environmental remediation efforts, where it could potentially contribute to the management of microbial populations in contaminated environments.

Glycerol monolaurate (GML) mechanism is that lauric acid can cause viral membrane protein leakage, monolaurate can be inserted into the membrane of the virus, both of which lead to reduced or loss of replication.
Glycerol monolaurate (GML) is commonly said that monoglyceride destroys the membrane structure of the virus and inhibits its ability to replicate, that is, it leaves the virus in a half-dead resting state, in which the non-replicating virus acts as an antigen and stimulates the production of corresponding antibodies in animals.
Glycerol monolaurate (GML) is used in baked product extensively, having the function for increase the quality of rice and flour production.

Glycerol monolaurate (GML) in capsule form as a dietary supplement.
Glycerol monolaurate (GML) is sold as a dietary supplement and as an ingredient in certain foods.
The United States Food and Drug Administration categorizes it as generally recognized as safe.

Glycerol monolaurate (GML) is used as an emulsifier in sanitarian foods and other foods such as bread, cake, streamed bread and moon-cake.
Glycerol monolaurate (GML) is used in meat product, dairy product, spicy products and fruit and vegetable for make the time of preservation longer.
Glycerol monolaurate (GML) 90% is used to improve the texture and uniformity of baked goods like cakes, bread, and pastries.

Glycerol monolaurate (GML) is often used to increase the stability of dairy products such as cheese, cream, and ice cream.
Glycerol monolaurate (GML) plays a significant role in the food industry, where it is widely used as a food additive and preservative.
In addition to its applications in the food industry, Glycerol monolaurate (GML) is also utilized in the production of cosmetics and personal care products.

Glycerol monolaurate (GML) can be found in items such as lotions, creams, and soaps, where it acts as an emulsifier, helping to blend different ingredients together and create stable formulations.
Glycerol monolaurate (GML) even finds its way into animal feeds. Its antimicrobial properties make it a valuable additive in animal nutrition, helping to protect animals from harmful bacteria and fungi that can affect their health and well-being.
Glycerol monolaurate (GML) is used as an emulsifier to create uniformity and to keep the product from separating.

Glycerol monolaurate (GML) is used to improve the texture and mouthfeel of snack foods, such as cookies, crackers, and candy.
Glycerol monolaurate (GML) is used in sports drinks and protein shakes to prevent separation and improve the mouthfeel.
Glycerol monolaurate (GML) is used in salad dressings, mayonnaise, and sauces to improve the emulsification and texture.

Glycerol monolaurate (GML) is used as an antimicrobial agent in food products to inhibit the growth of spoilage microorganisms, extending the shelf life of items like baked goods, dairy products, and beverages.
Glycerol monolaurate (GML) acts as an emulsifier and stabilizer in food products, particularly in items where oil and water need to be combined and maintained in a stable state, such as salad dressings and mayonnaise.
Glycerol monolaurate (GML) is utilized in cosmetics and personal care products as an emulsifying agent to blend water and oil-based ingredients, enhancing product stability and texture.

Glycerol monolaurate (GML) helps stabilize formulations, preventing separation of components and maintaining product integrity.
Glycerol monolaurate (GML) is added to animal feed as an antimicrobial agent to control microbial growth and improve the hygiene of the feed, contributing to animal health.
Glycerol monolaurate (GML) is explored for use in pharmaceuticals and drug delivery systems, particularly in encapsulation technologies where it can encapsulate and release bioactive compounds.

Glycerol monolaurate (GML) may be found in topical formulations, such as creams and lotions, for its potential antimicrobial and anti-inflammatory effects on the skin.
Glycerol monolaurate (GML)'s surfactant properties make it suitable for use in certain detergent formulations, contributing to emulsification and stabilization.
Glycerol monolaurate (GML) is available as a dietary supplement, marketed for its potential health benefits, including immune system support.

Glycerol monolaurate (GML)'s potential therapeutic applications, including its antimicrobial, anti-inflammatory, and immunomodulatory properties.
Glycerol monolaurate (GML) may be explored for its antimicrobial properties in water treatment processes to control bacterial contamination.
Glycerol monolaurate (GML) is generally considered biodegradable, contributing to its use in formulations where environmental considerations are important.

Glycerol monolaurate (GML) is involved in encapsulation technologies, where it can be utilized to encapsulate and deliver bioactive compounds in controlled-release systems.
Ongoing studies investigate Glycerol monolaurate (GML)'s impact on gut health, influencing the gut microbiota and potentially offering benefits in maintaining a balanced microbial environment.
Glycerol monolaurate (GML) has been studied for its potential antiviral properties.

Research suggests Glycerol monolaurate (GML) may have inhibitory effects on certain viruses, making it a subject of interest in antiviral formulations.
Glycerol monolaurate (GML) is utilized as a food additive in various food products.
Glycerol monolaurate (GML) may serve multiple functions, including emulsification, stabilization, and as an antimicrobial agent for food preservation.

Glycerol monolaurate (GML) may be included in the formulation of functional foods, where its potential health benefits, such as antimicrobial and anti-inflammatory properties, can contribute to the overall functionality of the product.
Due to its antimicrobial properties, Glycerol monolaurate (GML) may find application in air fresheners and deodorizers to inhibit the growth of odor-causing bacteria.
Glycerol monolaurate (GML) is investigated for its potential use in biomedical coatings to prevent microbial contamination on surfaces of medical devices and implants.

In the oil and gas industry, Glycerol monolaurate (GML) may be explored for its ability to control microbial growth in oilfield processes, pipelines, and equipment.
Glycerol monolaurate (GML) is studied for its potential use in the poultry industry to control bacterial contamination and improve hygiene in poultry feed and processing.
Glycerol monolaurate (GML) may be considered in the plastic industry for its potential antimicrobial properties, contributing to the development of antimicrobial plastics in various applications.

Glycerol monolaurate (GML)'s antimicrobial properties may be explored in pesticide formulations to enhance their efficacy and control microbial populations in agricultural settings.
In industrial applications such as metalworking, Glycerol monolaurate (GML) may be considered for its potential use in metalworking fluids to inhibit microbial growth and prevent degradation.
Glycerol monolaurate (GML) can be used in the textile industry as an antimicrobial agent, contributing to the development of textiles with enhanced resistance to microbial growth and odors.

Glycerol monolaurate (GML) may be incorporated into anti-acne formulations in skincare products due to its antimicrobial properties, potentially aiding in the control of acne-causing bacteria.
Glycerol monolaurate (GML)'s emulsifying properties make it suitable for use in water-based coatings, contributing to stability and performance in various coating applications.
Glycerol monolaurate (GML)'s stability and antimicrobial properties may be explored in heat transfer fluids, contributing to the prevention of microbial contamination in industrial heat exchange systems.

Safety Profile:
Glycerol monolaurate (GML) may cause irritation to the skin and eyes, especially in its pure form or at high concentrations.
Direct contact with the skin or eyes should be avoided, and appropriate personal protective equipment, such as gloves and safety goggles, should be used.
Inhalation of Glycerol monolaurate (GML) dust or vapors may lead to respiratory irritation.

Adequate ventilation is important in areas where GML is handled to minimize the risk of inhalation exposure.
Glycerol monolaurate (GML) is generally regarded as safe for consumption in regulated amounts, ingesting large quantities could lead to gastrointestinal discomfort.
Ingestion should be avoided, and Glycerol monolaurate (GML)-containing products should be used according to recommended guidelines.

Some individuals may be sensitive or allergic to Glycerol monolaurate (GML), and exposure could lead to allergic reactions.
Glycerol monolaurate (GML)'s important to be aware of any known allergies or sensitivities when using products containing Glycerol monolaurate (GML).

Environmental Impact:
Glycerol monolaurate (GML) is considered biodegradable, but large spills or improper disposal could have environmental consequences.
Glycerol monolaurate (GML)'s important to follow proper waste disposal procedures in accordance with local regulations.
Glycerol monolaurate (GML) may release products that could be harmful.

Synonyms:
Monolaurin
2,3-Dihydroxypropyl dodecanoate
142-18-7
1-Monolaurin
Glyceryl monolaurate
Lauricidin
GLYCERYL LAURATE
1-Glyceryl laurate
Glycerol 1-laurate
27215-38-9
1-Monolauroyl-rac-glycerol
1-Monododecanoylglycerol
Glycerol monolaurate (GML)
Laurin, 1-mono-
Glycerin 1-monolaurate
Glycerol 1-monolaurate
Lauric acid 1-monoglyceride
Dodecanoic acid, 2,3-dihydroxypropyl ester
2,3-Dihydroxypropyl laurate
Glyceryl monododecanoate
1-Lauroyl-rac-glycerol
DL-alpha-Laurin
Glycerides, C12-18
.alpha.-monolaurin
67701-26-2
3-Dodecanoyloxy-1,2-propanediol
(+-)-Glyceryl 1-monododecanoate
Dodecanoic acid alpha-monoglyceride
glyceryl 1-laurate
Glycerin monolaurate
(+-)-2,3-Dihydroxypropyl dodecanoate
Dodecanoic acid, monoester with 1,2,3-propanetriol
Glycerol .alpha.-monolaurate
WR963Y5QYW
40738-26-9
DTXSID5041275
CHEBI:75543
Lauric acid .alpha.-monoglyceride
1-Monolaurin;1-Lauroyl-rac-glycerol
Lauric acid, monoester with glycerol
Dodecanoic acid .alpha.-monoglyceride
NSC698570
NSC-698570
NCGC00164528-01
alpha-Monolaurin
1-monolauroylglycerol
DTXCID3021275
Glucerol alpha-monolaurate
Monolauroylglycerin
CAS-142-18-7
Lauric acid alpha-monoglyceride
C15H30O4
EINECS 205-526-6
UNII-WR963Y5QYW
Lauricidin R
Cithrol GML
rac-1-monolaurin
MG 12:0
Hodag GML
Glycerox L 8
Lauricidin 802
Lauricidin 812
1-dodecanoylglycerol
EINECS 266-944-2
Grindtek ML 90
Dimodan ML 90
Imwitor 312
Sunsoft 750
Sunsoft 757
Monomuls 90L12
rac-1-lauroylglycerol
Aldo MLD-K-FG
Glycerol 1-dodecanoate
Tegin L 90
rac-1-dodecanoylglycerol
AI3-03482
SDA 16-001-00
rac-1-monolauroylglycerol
Glycerol alpha-monolaurate
Poem M 300
EC 205-526-6
EC 266-944-2
Glycerol monolaurate (GML) (VAN)
Glycerol .alpha.-dodecanoate
SCHEMBL16042
MLS004773952
2,3-Dihydroxypropyl laurate #
CHEMBL510533
CHEBI:75539
GLYCEROL 1-MONODODECANOATE
1-Lauroyl-rac-glycerol, >=99%
UNII-Y98611C087
1,2,3-Propanetriol 1-dodecanoate
MAG 12:0
NSC 4837
rac-2,3-dihydroxypropyl dodecanoate
EINECS 248-337-4
Tox21_112159
Tox21_300759
MFCD00037815
(.+/-.)-Glyceryl 1-monododecanoate
AKOS016005827
Dodecanoic acid,3-dihydroxypropyl ester
NCGC00164528-02
NCGC00164528-03
NCGC00164528-04
NCGC00254663-01
5-TRIFLUOROMETHYL-2-PYRIMIDINAMINE
AS-60593
NCI60_035284
SMR001254002
(+/-)-GLYCERYL 1-MONODODECANOATE
(.+/-.)-2,3-Dihydroxypropyl dodecanoate
HY-121620
FT-0625428
FT-0626744
FT-0774814
G0081
M 300
Y98611C087
(+/-)-2,3-DIHYDROXYPROPYL DODECANOATE
H10813
L-1475
A885218
Q2113676

DESCRIPTION:

1-monostearoylglycerol is a 1-monoglyceride that has stearoyl as the acyl group.
Glycerol monostearate (GMS) has a role as an algal metabolite and a Caenorhabditis elegans metabolite.
Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid .


CAS: 123-94-4
European Community (EC) Number: 250-705-4
IUPAC Name: 2,3-dihydroxypropyl octadecanoate
Molecular Formula: C21H42O4



Glycerol monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.
Glycerol monostearate takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Chemically it is the glycerol ester of stearic acid.
Glycerol monostearate is also used as hydration powder in exercise formulas


Glycerol monostearate (GMS) is commonly used as an emulsifier in foods.
Glyceryl monostearate is a natural product found in Aristolochia cucurbitifolia, Lobelia longisepala, and other organisms with data available.


Glyceryl monostearate (GMS) is an effective emulsifier used in the baking industry available in the form of small beads, flakes, or powders.
In addition to emulsification, Glycerol monostearate (GMS) is a thickening agent and a stabilizer.
In baking, Glycerol monostearate (GMS) is used to improve dough quality and stabilize fat/protein emulsions.



Glyceryl monostearate (GMS) is a waxy ingredient that is obtained from coconuts, palm kernels, or olives.
Glyceryl monostearate (GMS) is usually pale yellow or white in color.
Glyceryl monostearate (GMS) is used in skin care and cosmetic products because of its great moisturizing properties.

Glyceryl monostearate (GMS) traps moisture on the skin and hair to prevent dehydration and damage.
Moreover, Glyceryl monostearate (GMS) also binds other ingredients together in a formulation.
Further, this ingredient is mildly comedogenic and may cause acne on some skin types.
The chemical formula of Glyceryl monostearate (GMS) is C21H42O4.



Glyceryl monostearate is a self emulsifying wax.
Glyceryl monostearate (GMS) is located in dozens of personal care products, including moisturizers, eye cream, sunscreen, makeup and hand creams.
Direct Chems provide Glyceryl monostearate (GMS) SE which is self emulsifying in pearl form and can be used as a viscosity enhancer adding emollient properties which makes skin softer and supple.


Glyceryl monostearate (GMS) also acts as a fast penetrating emollient which helps retain hydration, lubricate, condition and soften skin.
They slow loss of moisture so is ideal when adding to natural formulations.
The presence of Glyceryl monostearate (GMS) enables other ingredients in the formulation to continue functioning effectively in order to excel their beneficial properties by extending shelf life, preventing products from freezing and developing crusts on the surface.
One important factor is Glyceryl monostearate (GMS) allows oils to be added to products but decreases the greasiness so the final product is a smooth, creamy texture.


STRUCTURE, SYNTHESIS, AND OCCURRENCE OF GLYCEROL MONOSTEARATE (GMS):
Glyceryl monostearate (GMS) exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.
Typically these are encountered as a mixture as many of their properties are similar.

Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol.
Glyceryl monostearate (GMS) occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.
Glyceryl monostearate (GMS) is present at very low levels in certain seed oils




ORIGIN OF GLYCERYL MONOSTEARATE (GMS):
The first known emulsifier was egg yolk, often used to disperse liquid oil into an acidic aqueous phase.
Mono- and diglycerides were first synthesized in 1853 and were extensively used in shortening and margarine formulations by the 1930s.


COMPOSITION OF GLYCERYL MONOSTEARATE (GMS):
Glyceryl monostearate (GMS) is a non-ionic ester of glycerol and stearic acid.
Glyceryl monostearate (GMS) is soluble in ethanol at 122°F (50°C) but immiscible with water.
Glyceryl monostearate (GMS) often consists of a mixture of mono, di, and triesters of fatty acids occurring in food oils and fats.
They may contain small amounts of free fatty acids and glycerol.



COMMERCIAL PRODUCTION OF GLYCERYL MONOSTEARATE (GMS):
Glyceryl monostearate (GMS) is produced either through heating oils/fats with excess glycerol or by direct esterification of glycerol (of animal or plant sources) with stearic acid.
The proportion of monoester formed is dependent on the proportion of glycerol and reaction temperature range of 86-140°F (60-80°C).
Further purification is carried out by high vacuum distillation.



FUNCTION OF GLYCERYL MONOSTEARATE (GMS):
The ratio of hydrophilic to lipophilic moieties, called hydrophilic-lipophilic balance (HLB) is used in classifying emulsions.
HLB values range from 0-20 with lower values indicating dominant lipophilic character while higher values indicate hydrophilic character.
GMS has a HLB value of 3.8, making it lipophilic and suitable for uses in w/o emulsions, such as batters and doughs, dairy and other products.

Glyceryl monostearate (GMS) is used in a paste form, i.e. mixed with water and other ingredients to improve gel stability.
Glyceryl monostearate (GMS) is an unsaturated monoglyceride and offers better stability than other unsaturated monoglycerides, such as oleic acid.

Glyceryl monostearate (GMS) is used in the baking industry to:
Help in the formation and maintenance of uniform dispersions of immiscible solvents.
Stabilize emulsions via displacing proteins from oil, wax or solvent surfaces.


Improve bread texture, and retard staling due to its complexation with starch amylopectin
Improve aeration of doughs and batters.


APPLICATIONS OF GLYCERYL MONOSTEARATE (GMS):
Glyceryl monostearate (GMS) has been used in the following applications:
To improve the physical and rheological properties of the batter and thus better-quality cakes
In breads such as pain courant Français, Friss búzakenyér, naan and roti

In sponge cakes and pancakes for aeration.
Dairy products such as cream, whipped cream, ice cream, cream powder, imitation creams, etc.
Fruit/vegetable spreads, jams, jellies, marmalades



Application in plastics industry:

Glyceryl monostearate (GMS) is used As a lubricant, anti-static agent, non-toxic plasticizer, anti-aging in the production of polymers, plastics and packaging films.
Glyceryl monostearate (GMS) Can improve the flexibility, plasticity and anit-static properties.

Glyceryl monostearate (GMS) Is used e.g. in the manufacturing of of polypropylene-caps to provide a slip/lubricant effect in addition to anti-static effect.
Glyceryl monostearate (GMS) In agriculture plastic films as anti fogging agent.

Glyceryl monostearate (GMS) is used as a process aid in production of expanded polyethylene to improve gas
exchange.


PRODUCT BENEFITS OF GLYCERYL MONOSTEARATE (GMS):

Glyceryl monostearate (GMS) Reduces the friction during the extrusion process, giving a uniform cell size distribution and is improving the gas exchange.
Glyceryl monostearate (GMS) is compatible with anionic, cationic and non-ionic surfactants and has exceptional electrolyte tolerance.
Glyceryl monostearate (GMS) has effects of emulsification, dispersion, foaming, defoaming, starch antiaging.


Product dosing:
We strongly recommend testing of your own system under the actual conditions of processing and end-use prior to full scale testing.
Exact loading must be determined by composition of the specific polymer system.


Other applications:

Cosmetic uses, as a co-emulsifier of emulsions, to modify viscosity and improve stability.
Glyceryl monostearate (GMS) is used As an emulsifier in the production of foods, including ice cream, chewing gum, toffee, shortening, margarine, starch etc.

Anti-aging agent for starch.
Protective coating for hygroscopic powders.











USES OF GLYCERYL MONOSTEARATE (GMS):
Glyceryl monostearate (GMS) provides multiple benefits for the skin and hair.
This is why Glyceryl monostearate (GMS) is used in thousands of cosmetic, skin care, and hair care products such as skin cleansers, foundations, eyeliners, and shampoos.

Skin care:
Glyceryl monostearate (GMS) is a humectant that draws water to the top most layer of the skin and binds it there to provide intense hydration.
Glyceryl monostearate (GMS) also acts as a thickener to maintain the texture and spreadability of the products

Hair care:
Glyceryl monostearate (GMS) is used to bring luster and shine to the shafts by bringing back the lost water content.
This ingredient also has foaming properties that make it a great choice for products such as shampoos


Cosmetic products:
Glyceryl monostearate (GMS) acts as a surfactant.
Glyceryl monostearate (GMS) is a good preservative that keeps cosmetic products from going bad by increasing their shelf life.
Cosmetics with Glyceryl monostearate (GMS) do not dry easily and provide hydration to the skin


Glyceryl Monostearate (GMS) is a mixture of monoacylgcerols, mostly monosteroylglycerol, together with quantities of di-and triacylglycerols.
In the Ph.Eur, Glyceryl monostearate is distinguished into different grades, namely Type I, II and III depending on their fatty acid composition.
When supplied as an excipient, Glyceryl monostearate occurs as a hard, waxy mass or greasy powder, flakes or beads.


APPLICATIONS IN PHARMACEUTICAL FORMULATIONS OR TECHNOLOGY:
Glyceryl monostearate is principally used as an emollient, mild emulsifying agent, solubilizing agent, stabilizing agent, and tablet and capsule lubricant.
Owing to its lipid nature as well as the availability of many different grades, Glyceryl monostearate exhibits thickening, emulsifying and protective properties, making it a versatile excipient across multiple applications and dosage forms.

A summary of the different applications of Glyceryl monostearate in food, pharmaceutical, and cosmetic applications is outlined below:
• Formulation stabilizer (for water-in-oil emulsions containing polar and nonpolar ingredients)
• Dispersant for pigments in oils or solids in fats
• Solvent and co-solvent for phospholipids, such as lecithin
• Hot melt granulation excipient
• Matrix former for sustained-release tablets
• Lubricant for tablets
• Suppository base
• Hydrophobic agent in tablet coatings (prevents tablet sticking)

Incidences of polymorph formation when Glyceryl monostearate is used in product formulation are an important consideration.
Generally, the α-form tends to disperse easily and foams, rendering it useful as an emulsifying agent.
The β-form, being more stable, is suitable for use in sustained-release matrices.


Note that Glyceryl monostearate is not an efficient emulsifier.
Its usefulness resides in the fact that it is a useful emollient and co-emulsifier.
It is readily emulsified by common emulsifying agents and by the incorporation of other fatty materials into the formulation.

When added to creams, Glyceryl monostearate imparts to creams smoothness, and fineness, while improving the formulation stability.

About Glyceryl Monostearate – Self-emulsifying
Self-emulsifying Glyceryl monostearate is a grade of Glyceryl monostearate to which an emulsifying agent has been added.
A specification for self-emulsifying Glyceryl monostearate was previously included in the Ph.Eur (it still remains in the B.P).
This material is mainly used as an emulsifying agent for oils, fats, solvents, and waxes.
CHEMICAL CHARACTERISTICS
• Thickening agent
• Emulsifier
• Preservant
• Surfactant
• Moisturizer
• Dispersant
• Emollient
• Lubricant
• Anti-caking agent


AREAS OF APPLICATIONS
• Food manufacturing and beverage industry
• Textile industry
• Plastic industry
• Pharmaceuticals
• Cosmetics
• Personal care products



PRODUCT FEATURES
• Eco-friendly
• Water insoluble
• High Efficiency
• Non-toxic
• Cost competitive








SAFETY INFORMATION ABOUT GLYCEROL MONOSTEARATE (GMS):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




CHEMICAL AND PHYSICAL PROPERTIES OF GLYCEROL MONOSTEARATE (GMS):
Molecular Weight
358.6 g/mol
XLogP3
7.4
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Rotatable Bond Count
20
Exact Mass
358.30830982 g/mol
Monoisotopic Mass
358.30830982 g/mol
Topological Polar Surface Area
66.8Ų
Heavy Atom Count
25
Formal Charge
0
Complexity
281
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
1
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
Physical form, Solid, powder
Appearance, White or whitish, waxy solid
HLB Value, 3 (IMWITOR® 900 K)
Flash point, 240oC
Melting point, 55-60 oC
Boiling point, 238-240 oC
Relative density, 1.03 g/ml
Solubility, Insoluble in water
Melting point, 78-81 °C
Boiling point, 410.96°C (rough estimate)
Density, 0.9700
refractive index, 1.4400 (estimate)
storage temp., Sealed in dry,Store in freezer, under -20°C
solubility, Soluble in hot ethanol, ether, chloroform, hot acetone, mineral oil, and fixed oils. Practically insoluble in water, but may be dispersed in water with the aid of a small amount of soap or other surfactant.
form, Powder
color, Pure-white or cream-colored, wax-like solid
Odor, faint odor
Water Solubility, Soluble in hot organic solvents.Soluble in hot water. Slightly soluble in ethanol. Insoluble in aliphatic solvents.
Content of monoester (%):, Min. 95
Colour (Hazen):, Max. 190
Iodine value (gI2/100g):, Max. 3.0
Melting range (°C):, 60.0 - 70.0
Free acid (stearic acid) (%):, Max. 2.5
Free glycerol (%):, Max. 1.2
Water (%):, Max. 0.3
Arsenic (ppm):, Max. 1
Heavy metals (Pb, ppm):, Max. 5




SYNONYMS OF GLYCEROL MONOSTEARATE (GMS):
glyceryl monostearate
monostearin
Glyceryl monostearate
123-94-4
Monostearin
GLYCEROL MONOSTEARATE
31566-31-1
Glyceryl stearate
Tegin
1-Stearoyl-rac-glycerol
1-MONOSTEARIN
Glycerin 1-monostearate
Stearin, 1-mono-
Stearic acid 1-monoglyceride
2,3-dihydroxypropyl octadecanoate
Glycerol 1-monostearate
1-Glyceryl stearate
Glycerin 1-stearate
Sandin EU
1-Monostearoylglycerol
Octadecanoic acid, 2,3-dihydroxypropyl ester
Aldo MSD
Aldo MSLG
Glyceryl 1-monostearate
Stearoylglycerol
Glycerol 1-stearate
alpha-Monostearin
Tegin 55G
Emerest 2407
Aldo 33
Aldo 75
Glycerin monostearate
Arlacel 165
3-Stearoyloxy-1,2-propanediol
Cerasynt SD
Stearin, mono-
2,3-Dihydroxypropyl stearate
.alpha.-Monostearin
Monoglyceryl stearate
Glycerol alpha-monostearate
Cefatin
Dermagine
Monelgin
Sedetine
Admul
Orbon
Citomulgan M
Drewmulse V
Cerasynt S
Drewmulse TP
Tegin 515
Cerasynt SE
Cerasynt WM
Cyclochem GMS
Drumulse AA
Protachem GMS
Witconol MS
Witconol MST
FEMA No. 2527
Glyceryl stearates
Monostearate (glyceride)
Unimate GMS
Glyceryl monooctadecanoate
Ogeen M
Emcol CA
Emcol MSK
Hodag GMS
Ogeen GRB
Ogeen MAV
Aldo MS
Aldo HMS
Armostat 801
Kessco 40
Stearic monoglyceride
Abracol S.L.G.
Arlacel 161
Arlacel 169
Imwitor 191
Imwitor 900K
NSC 3875
11099-07-3
Atmul 67
Atmul 84
Starfol GMS 450
Starfol GMS 600
Starfol GMS 900
Cerasynt 1000-D
Emerest 2401
Aldo-28
Aldo-72
Atmos 150
Atmul 124
Estol 603
Ogeen 515
Tegin 503
Grocor 5500
Grocor 6000
Glycerol stearate, pure
Stearic acid alpha-monoglyceride
Cremophor gmsk
Glyceryl 1-octadecanoate
Cerasynt-sd
Lonzest gms
Cutina gms
Lipo GMS 410
Lipo GMS 450
Lipo GMS 600
glycerol stearate
1-MONOSTEAROYL-rac-GLYCEROL
Nikkol mgs-a
Glyceryl monopalmitostearate
USAF KE-7
1-octadecanoyl-rac-glycerol
EMUL P.7
EINECS 204-664-4
EINECS 245-121-1
UNII-230OU9XXE4
Stearic acid, monoester with glycerol
Glycerol .alpha.-monostearate
Glyceroli monostearas
Glycerol monostearate, purified
Imwitor 491
Sorbon mg-100
22610-63-5
Cithrol gms 0400
UNII-258491E1RZ
NSC3875
Stearic acid .alpha.-monoglyceride
(1)-2,3-Dihydroxypropyl stearate
MONOSTEARIN (L)
NSC-3875
1-Monooctadecanoylglycerol
EINECS 250-705-4
1,2,3-Propanetriol monooctadecanoate
Octadecanoic acid, ester with 1,2,3-propanetriol
GLYCERYL 1-STEARATE
1-O-Octadecanoyl-2n-glycerol
AI3-00966
MG(18:0/0:0/0:0)[rac]
230OU9XXE4
DTXSID7029160
CHEBI:75555
EC 250-705-4
GLYCERYL MONOSTEARATE 40-50
Octadecanoic acid, monoester with 1,2,3-propanetriol
258491E1RZ
1-Stearoyl-rac-glycerol (90per cent)
83138-62-9
NCGC00164529-01
(+/-)-2,3-DIHYDROXYPROPYL OCTADECANOATE
DTXCID909160
Octadecanoic acid, 2,3-dihydroxypropyl ester, (A+/-)-
MFCD00036186
Celinhol - A
CAS-123-94-4
Myvaplex 600
rac-Glycerol 1-stearate
C21H42O4
1-Monooctadecanoyl-rac-glycerol
Celinhol-A
Glyceryl monostearate [JAN:NF]
MG 18:0
(+/-)-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
Eastman 600
1-O-stearoylglycerol
1-octadecanoylglycerol
85666-92-8
rac-octadecanoylglycerol
glycerol 1-octadecanoate
rac-glyceryl monostearate
Glycerol .alpha.-sterate
rac-1-monostearoylglycerol
DSSTox_CID_9160
Monoglycerides, c16-18
(+-)-1-stearoylglycerol
SCHEMBL4488
(+-)-glyceryl monostearate
Geleol mono and diglycerides
DSSTox_RID_78757
DSSTox_GSID_29304
Glycerol monostearate (GMS)
(+-)-1-monostearoylglycerol
(+-)-1-octadecanoylglycerol
Glycerides, C16-18 mono-
Glycerol monostearate 40-55
GLYCERYL STEARATE (II)
CHEMBL255696
2,3-Dihydroxypropyl stearate #
DTXSID7027968
CHEBI:75557
1-Stearoyl-rac-glycerol (90%)
GLYCERYL MONOSTEARATE (II)
Glyceryl monostearate (JP17/NF)
1-Stearoyl-rac-glycerol, >=99%
MAG 18:0
EINECS 238-880-5
EINECS 293-208-8
Tox21_112160
Tox21_202573
Tox21_301104
LMGL01010003
rac-2,3-dihydroxypropyl octadecanoate
AKOS015901589
Tox21_112160_1
DB11250
(+-)-2,3-dihydroxypropyl octadecanoate
NCGC00164529-02
NCGC00164529-03
NCGC00164529-04
NCGC00255004-01
NCGC00260122-01
Octadecanoic acid,3-dihydroxypropyl ester
1,2,3-Propanetriol 1-octadecanoyl ester
BS-50505
CAS-11099-07-3
FT-0626740
FT-0626748
FT-0674656
G0085
Octadecanoic acid, 2.3-dihydroxypropyl ester
D01947
EC 293-208-8
F71433
S-7950
A890632
A903419
SR-01000944874
Q-201168
Q5572563
SR-01000944874-1
W-110285
()-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
342394-34-7
InChI=1/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H

Glycerol Monostearate (GMS) takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Glycerol Monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier and thickener.
Glycerol Monostearate (GMS) is derived from glycerol (glycerin) and stearic acid, a saturated fatty acid.

CAS Number: 123-94-4
Molecular Formula: C21H42O4
Molecular Weight: 358.56
EINECS Number: 204-664-4

Glycerol Monostearate (GMS), also called monstearin or glyceryl stearate, is a hard, waxy mass, powder or flake ingredient, which is typically white.
Glycerol Monostearate (GMS) is derived from vegetable oils.
Glycerol Monostearate (GMS)e is often used as an emulsifier.

Glycerol Monostearate (GMS) is found in dozens of personal care products, such as moisturizers, eye cream, sunscreen, makeup, hand cream, and other products.
Glycerol Monostearate (GMS) is also used in foods as a thickener.
Glycerol Monostearate (GMS), also known as glyceryl monostearate or mono-and diglycerides of fatty acids (E471 when used as a food additive), is a chemical compound commonly used in various industries, including the food industry and cosmetics.

Glycerol Monostearate (GMS) appears as a white or slightly yellowish waxy solid or powder at room temperature.
Glycerol Monostearate (GMS) is a long chain molecule typically occurring in the body as a by-product of the breakdown of fats.

Glycerol Monostearate (GMS) is one of the panels of serum metabolic biomarkers for detecting and diagnosing cancer, especial ovarian cancer.
Glycerol Monostearate (GMS) is also used in the development of drug delivery vehicles such as nanoparticles and microemulsions.
Glycerol Monostearate (GMS) can also be used as an emulsifying agent, which allows the suspension of pharmaceuticals in a biodegradable form.

Glycerol Monostearate (GMS) is an effective emulsifier used in the baking industry available in the form of small beads, flakes, or powders.
In addition to emulsification, GMS is a thickening agent and a stabilizer.
Glycerol Monostearate (GMS), commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.

Glycerol Monostearate (GMS) takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Chemically it is the glycerol ester of stearic acid.
Glycerol Monostearate (GMS) is also used as hydration powder in exercise formulas.

Glycerol Monostearate (GMS) exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.
Typically these are encountered as a mixture as many of their properties are similar.
Glycerol Monostearate (GMS) is a fatty acid ester seen in food, cosmetics, and beauty products (hair and skin) for various uses, including as a: thickening agent, emulsifier, anti-sticking agent, dispersing agent, solvent, greasing agent, and perfume dilutant.

Glycerol Monostearate (GMS) is a Glyceryl Ester; Glyceryl Monostearate specifically occurs naturally in the body and fatty foods and is formed during the breakdown of fats in the body.
When applied topically, Glycerol Monostearate (GMS) constituent makes Glyceryl Stearate a fast-penetrating emollient that helps create a protective barrier on the skin's surface.
This helps retain hydration and slow the loss of moisture.

This reduced rate of water evaporation helps to lubricate, condition, soften, and smooth the skin.
Glycerol Monostearate (GMS)s protective properties extend to its antioxidant qualities, which help protect the skin against damage caused by free radicals.
When added to natural formulations, Glycerol Monostearate (GMS) has stabilizing effects on the final product, which means it helps the other ingredients in the formulation continue functioning effectively to exhibit their beneficial properties.

In this way, it helps to balance the product’s pH value and thereby prevents the product from becoming overly acidic or alkaline.
Glycerol Monostearate (GMS) also helps increase shelf life, prevents products from freezing or from developing crusts on their surfaces, and it helps lessen the greasy nature of some oils that may be added to cosmetics formulations.
In formulations that are oil-based, the thickening properties of Glycerol Monostearate (GMS) help to scale down the need for co-emulsifiers and, in emulsions with big water phases, Glyceryl Stearate can help develop liquid crystal phases as well as crystalline gel phases.

As an opacifier, Glycerol Monostearate (GMS) makes transparent or translucent preparations opaque, thus protecting them from or increasing their resistance to being penetrated by visible light.
This also helps to boost or balance the appearance of pigments and improve the final product's density for a luxuriously smooth and creamy texture.
Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol.

Glycerol Monostearate (GMS) occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.
Glycerol Monostearate (GMS) is present at very low levels in certain seed oils.
Glycerol Monostearate (GMS) is a non-ionic ester of glycerol and stearic acid.

Glycerol Monostearate (GMS) is soluble in ethanol at 122°F (50°C) but immiscible with water.
Glycerol Monostearate (GMS) often consists of a mixture of mono, di, and triesters of fatty acids occurring in food oils and fats.
They may contain small amounts of free fatty acids and glycerol.

Glycerol Monostearate (GMS) is produced either through heating oils/fats with excess glycerol or by direct esterification of glycerol (of animal or plant sources) with stearic acid.
The proportion of monoester formed is dependent on the proportion of glycerol and reaction temperature range of 86-140°F (60-80°C).
Further purification is carried out by high vacuum distillation.

Glycerol Monostearate (GMS) is a self emulsifying wax. It is located in dozens of personal care products, including moisturizers, eye cream, sunscreen, makeup and hand creams.
Direct Chems provide Glycerol Monostearate (GMS) SE which is self emulsifying in pearl form and can be used as a viscosity enhancer adding emollient properties which makes skin softer and supple.
Glycerol Monostearate (GMS), commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.

Glycerol Monostearate (GMS) takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Chemically Glycerol Monostearate (GMS) is the glycerol ester of stearic acid.
Glycerol Monostearate (GMS) exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.

Typically these are encountered as a mixture as many of their properties are similar.
Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol.
Glycerol Monostearate (GMS) occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.

Glycerol Monostearate (GMS) is present at very low levels in certain seed oils.
Glycerol Monostearate (GMS) is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a
protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.
Glycerol Monostearate (GMS) is also used in cosmetics and hair-care products.

Glycerol Monostearate (GMS) is largely used in baking preparations to add "body" to the food.
Glycerol Monostearate (GMS) is somewhat responsible for giving ice cream and whipped cream their smooth texture.
Glycerol Monostearate (GMS) is sometimes used as an antistaling agent in bread.

Glycerol Monostearate (GMS) can also be used as an additive in plastic, where GMS works as an antistatic and antifogging agent.
Glycerol Monostearate (GMS) also acts as a fast penetrating emollient which helps retain hydration, lubricate, condition and soften skin.
They slow loss of moisture so is ideal when adding to natural formulations.

The presence of Glycerol Monostearate (GMS) enables other ingredients in the formulation to continue functioning effectively in order to excel their beneficial properties by extending shelf life, preventing products from freezing and developing crusts on the surface.
One important factor is Glycerol Monostearate (GMS) allows oils to be added to products but decreases the greasiness so the final product is a smooth, creamy texture.
Glycerol Monostearate (GMS), commonly known as GMS, is an organic molecule used as an emulsifier.

Glycerol Monostearate (GMS) is a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Glycerol Monostearate (GMS) is a glycerol ester of stearic acid.
Glycerol Monostearate (GMS) occurs naturally in the body as a by-product of the breakdown of fats, and is also found in fatty foods.

Glycerol Monostearate (GMS) is a food additive used as a thickening, emulsifying, anti-caking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.
Glycerol Monostearate (GMS) is also used in cosmetics and hair care products.
Glycerol Monostearate (GMS) is often used as an emulsifier, helping to combine ingredients that would normally not mix well, such as oil and water.

Glycerol Monostearate (GMS)'s used in products like salad dressings, mayonnaise, and creamy sauces to prevent separation and improve texture.
In baked goods like bread, cakes, and pastries, Glycerol Monostearate (GMS) can improve the texture, crumb structure, and moisture retention.
Glycerol Monostearate (GMS) helps create a softer and more tender texture in these products.

Glycerol Monostearate (GMS) can stabilize foams and whipped products, enhancing the volume and stability of products like whipped cream, meringues, and ice creams.
Glycerol Monostearate (GMS)can be used to prevent the formation of ice crystals in ice cream and frozen desserts, resulting in a smoother and creamier texture.
Glycerol Monostearate (GMS) can be used in reduced-fat or low-fat products to mimic some of the texture and mouthfeel lost when fat is reduced.

Glycerol Monostearate (GMS) can improve the quality of cake mixes by helping to disperse ingredients evenly and enhance the overall texture.
Glycerol Monostearate (GMS) can be used to stabilize and emulsify flavor oils in beverages, helping to create a consistent flavor experience.
Glycerol Monostearate (GMS) can be used in some candies and confections to improve texture, prevent crystallization, and provide a smoother mouthfeel.

Glycerol Monostearate (GMS) is a white or yellowish white, hard waxy mass or unctuous powder or flakes; odourless or slight, agreeable, fatty odour.
Glycerol Monostearate (GMS) should be kept in a tightly closed container, protected from light.
Glycerol Monostearate (GMS) may contain a suitable antioxidant.

Glycerol Monostearate (GMS) is a mixture of mono-, di- and triglycerides of stearic and palmitic acids.
Glycerol Monostearate (GMS) contains not less than the equivalent of 35.0% of monoglycerides, calculated as C20H40O4, and not morethan the equivalent of 6.0% of free glycerol.
Fatty acid esters, such as Glycerol Monostearate (GMS) and more particularly ‘high-mono GMS’ containing more than 95% monoester; GMS is in accordance with most food contact regulations.

Glycerol Monostearate (GMS) is a high-quality and high-efficiency edible emulsifier, which has the functions of emulsification, dispersion, stabilization, foaming, defoaming and starch anti-aging.
Glycerol Monostearate (GMS) is widely used the the manufacturing of ice cream, peanut butter, cake gel, bread and cakes.
Glycerol Monostearate (GMS), commonly referred to as GMS, is an odorless white flake with a sweet flavor profile.

Glycerol Monostearate (GMS) is produced by combining glycerin and stearic acid and has a minimum of 40% Monoglyceride content.
The primary application for Glycerol Monostearate (GMS) is to act as an emulsifier in foods such as breads, cakes, biscuits, margarine, shortening, peanut butter, among a wide range of other consumable goods that require an overall improvement in volume, texture, and consistency.
Glycerol Monostearate (GMS) is often added to food and beverage formulations to thicken the composition of a recipe in addition to preventing the product from drying out.

In addition to food and beverage manufacturing, Glycerol Monostearate (GMS) finds use for industrial applications.
Glycerol Monostearate (GMS) is an internationally recognized non-toxic, harmless and safe food ingredient used in various food processing.
In addition, Glycerol Monostearate (GMS) has a wider range of applications in the plastics industry, mainly used as mold release agents, plasticizers, antistatic additives, anti-shrinkage agents for plastic foam products, and internal lubricants in compound lead salt stabilizers.

In the production of PVC pipes and profiles, Glycerol Monostearate (GMS) is used as an internal lubricant instead of stearic acid, which reduces the surface precipitation of PVC products and acts as a plasticizer.
In recent years, Glycerol Monostearate (GMS) has been well used in the PVC pipe and profile industry.

Melting point: 78-81 °C
Boiling point: 476.9±25.0 °C(Predicted)
Density: 0.9678 g/cm3
FEMA: 2527 | GLYCERYL MONOSTEARATE
storage temp.: -20°C
solubility: Chloroform (Slightly)
form: Solid
pka: 13.16±0.20(Predicted)
color: White to Off-White
Odor: at 100.00 %. mild fatty waxy
Odor Type: fatty
JECFA Number: 918
Merck: 4489
BRN: 1728685
Hydrophilic-Lipophilic Balance (HLB): 5.5
InChIKey: VBICKXHEKHSIBG-UHFFFAOYSA-N
LogP: 7.23

Glycerol Monostearate (GMS) is widely used as an emulsifying agent in the food industry.
Glycerol Monostearate (GMS) helps mix ingredients that would otherwise separate, such as oil and water.
This property is particularly valuable in the production of various food products, including ice cream, salad dressings, and baked goods, where it can improve texture and stability.

Glycerol Monostearate (GMS) can act as a stabilizer, helping to prevent the crystallization of fats and oils in certain products.
This is especially important in frozen desserts like ice cream, where it enhances creaminess and prevents the formation of ice crystals.
Glycerol Monostearate (GMS) can also function as a thickening agent in food products, giving them a desirable texture or mouthfeel.

Glycerol Monostearate (GMS) is often used in cake batters, pudding, and other desserts to improve consistency.
Glycerol Monostearate (GMS) is utilized in cosmetics and personal care products, such as creams, lotions, and cosmetics, as an emulsifier, thickener, and moisturizing agent.
Glycerol Monostearate (GMS) helps create stable and creamy formulations.

Glycerol Monostearate (GMS) can serve as a binding agent in tablet production, helping to hold the active ingredients together and improve the tablet's disintegration properties.
Glycerol Monostearate (GMS) can be used as a processing aid in the production of plastics and rubber, where it can act as a lubricant, release agent, and antistatic agent.
Glycerol Monostearate (GMS) can be used as a softening agent for textiles and fabrics, improving their texture and feel.

Glycerol Monostearate (GMS) may be incorporated into paint and coating formulations to modify their rheological properties and improve their spreadability.
Glycerol Monostearate (GMS) is used in candle manufacturing as a wax additive to improve the candle's burn time and texture.
Glyceryl Monostearate (GMS) is a mixture of monoacylgcerols, mostly monosteroylglycerol, together with quantities of di-and triacylglycerols.

In the Ph.Eur, Glycerol Monostearate (GMS) is distinguished into different grades, namely Type I, II and III depending on their fatty acid composition.
When supplied as an excipient, Glycerol Monostearate (GMS) occurs as a hard, waxy mass or greasy powder, flakes or beads.
Glycerol Monostearate (GMS) is used in a paste form, i.e. mixed with water and other ingredients to improve gel stability.

Glycerol Monostearate (GMS) is an unsaturated monoglyceride and offers better stability than other unsaturated monoglycerides, such as oleic acid.
Glycerol Monostearate (GMS) is a single-tailed lipidic monoglyceride commonly used as a nontoxic food additive.
In this study, we have investigated Glycerol Monostearate (GMS), specifically its self-assembling properties and subsequent application in drug delivery.

Results from in silico modeling, corroborated by complementary small-angle neutron scattering, demonstrated vesicle formation; associated phase transitions were analyzed using differential scanning calorimetry; dynamic light scattering revealed particle size alterations that occurred in the transition region.
Spherical morphology of unilamellar vesicles was visualized using transmission electron microscopy imaging.
Further, hydrophilic and hydrophobic drug loading in GMS vesicles and their amenability to surface modification for hepatic targeting have, in this study, been both predicted through molecular simulation study and demonstrated experimentally.

The influence of hepatotropic ligands on the stability of drug-loaded Glycerol Monostearate (GMS) vesicles vis-à-vis cholesterol has also been investigated; the resulting GMS based drug delivery vehicle, its properties enhanced through surface decoration, is envisaged to achieve targeted delivery of its payload to hepatocytes.
Glycerol Monostearate (GMS) is a food additive used as a thickening, emulsifying, anti-caking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.

Glycerol Monostearate (GMS) is also used in cosmetics and hair care products.
Glycerol Monostearate (GMS) objective of the present investigation was to study the spontaneous self-assembling behavior of stearic acid in the presence of its monoglyceride and to evaluate its potential to be used as drug delivery vehicle.
Glycerol Monostearate (GMS) interesting feature of this system lies in spontaneous formation of vesicles on hydration of molten mixture of stearic acid (SA) and glyceryl monostearate (GMS) without using any solvent.

Glycerol Monostearate (GMS) 1H NMR spectrum of a sample was devoid of signals from fatty acid side chain protons, suggesting that upon interaction between SA and GMS, it adopts an orientation in which fatty acid side chains exists in hydrophobic domains separated from hydrophilic headgroup.
Glycerol Monostearate (GMS) is composed of naturally occuring lipid ingredients glycerol and stearic acid.
Fragrance ingredient, skin-conditioning agent - emollient, surfactant - emulsifying agent, emollient, and emulsifying Glycerol Monostearate (GMS), C21H42O4, also known as monostearin, is a mixture of variable proportions of glyceryl monostearate, glyceryl monopalmitate , and glyceryl esters of fatty acids present in commercial stearic acid.

Glyceryl Stearate, also referred to as Glycerol Monostearate (GMS), is a fatty acid derived from vegetable oil, Soy Oil, or Palm Kernel Oil; however, it is also naturally occurring in the human body.
This wax-like substance appears white or cream in color and is produced when Glycerol Monostearate (GMS) undergo esterification.
Traditionally, it is used in formulations for its emulsifying properties.

Glycerol Monostearate (GMS) also contains Sodium Stearate and/or Potassium Stearate.
The “SE” of Glyceryl Stearate SE stands for “Self-Emulsifying,” as it is a self-emulsifying form of Glycerol Monostearate (GMS).
While the names Glycerol Monostearate (GMS) and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades.

40–55 percent monoglycerides The PhEur 6.0 describes Glycerol Monostearate (GMS) 40–55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols.
Glycerol Monostearate (GMS) contains 40–55% of monoacylglycerols, 30–45% of diacylglycerols, and 5–15% of triacylglycerols.
This PhEur grade corresponds to mono- and di-glycerides USP– NF, which has similar specifications (not less than 40% monoglycerides).

90 percent monoglycerides The USP32–NF27 describes Glycerol Monostearate (GMS) as consisting of not less than 90% of monoglycerides of saturated fatty acids, chiefly glyceryl monostearate (C21H42O4) and glyceryl monopalmitate (C19H38O4).
The commercial products are mixtures of variable proportions of Glycerol Monostearate (GMS) and glyceryl monopalmitate.
Glycerol Monostearate (GMS) is a white to cream-colored, wax-like solid in the form of beads, flakes, or powder.

Glycerol Monostearate (GMS) is waxy to the touch and has a slight fatty odor and taste.
Glycerol Monostearate (GMS) is an emulsifier that helps form neutral, stable emulsions.
Glycerol Monostearate (GMS) is also a solvent, humectant, and consistency regulator in water-in-oil and oil-in-water formulations.

In addition, Glycerol Monostearate (GMS) can be used as a skin lubricant and imparts a pleasant skin feel.
Glycerol Monostearate (GMS) is a mixture of mono-, di-, and triglycerides of palmitic and stearic acids, and is made from glycerin and stearic fatty acids.
Derived for cosmetic use from palm kernel or soy oil, it is also found in the human body.

Glycerol Monostearate (GMS) is very mild with a low skin-irritation profile; however, a slight risk of irritation exists if products contain poor quality glyceryl stearate.
Glycerol Monostearate (GMS) is also known as monostearin, is a mixture of variable proportions of glyceryl monostearate, glyceryl monopalmitate, and glyceryl esters of fatty acids present in commercial stearic acid.
Glycerol Monostearate (GMS) prepared by glycerolysis of certain fats or oils that are derived from edible sources or by esterification, with glycerin, of stearic acid that is derived from edible sources.

Glycerol Monostearate (GMS) and Glyceryl StearatejSE are the esterification products of glycerine and stearic acid.
Glycerol Monostearate (GMS) contains excess stearic acid reacted with potassium hydroxide to produce a self-emulsifying product.
Both Glycerol Monostearate (GMS) and Glyceryl Stearate/SE are white to creamcolored wax-like solids.

Either ingredient may contain mono-, di-, and triglyceride impurities and fatty acid impurities.
Glycerol Monostearate (GMS) and Glyceryl StearateISE are widely used in cosmetic formulations as emollients, auxiliary emulsifiers, viscosifiers, stabilizers, bases, and surfactants.
Glycerol Monostearate (GMS) is used in more than 1200 cosmetic formulations at concentrations of rO.1-50%; Glyceryl Stearate/ SE is used in over 200 cosmetic products at concentrations of z 0.1-50%.
Glycerol Monostearate (GMS) is also widely used in foods as a surfactant, emulsifier, and thickener.

Glycerol Monostearate (GMS) is an antistalant and dough conditioner in breads and is also used in pharmaceutical bases.
Glycerol Monostearate (GMS) has been granted regulatory status as GRAS ingredient, an indirect food additive, a direct food additive, and as an OTC substance.
In acute oral toxicity studies in rats, Glycerol Monostearate (GMS) and Glyceryl Stearate/SE were nontoxic or mildly toxic.

In chronic studies, 15-25% Glycerol Monostearate (GMS) in the diet of rats for three consecutive generations had no adverse effects.
Rats fed a diet containing 25% Glycerol Monostearate (GMS) for two years developed renal calcifications.
Glycerol Monostearate (GMS) and Glyceryl Stearate/SE at concentrations of up to 100% were reported to be mildly irritating or nonirritating to the skin of rabbits.

In subchronic and chronic dermal toxicity tests, 4-5% Glycerol Monostearate (GMS) was nontoxic to rabbits but did cause moderate irritation (slight to moderate erythema, edema, atonia, desquamation, and/or fissuring).
In seven guinea pig sensitization studies, it was concluded that neither Glycerol Monostearate (GMS) nor Glyceryl Stearate/SE was capable of inducing sensitization.
In primary eye irritation studies, Glycerol Monostearate (GMS) and Glyceryl Stearate/SE at concentrations up to 100% were mildly irritating or nonirritating when instilled in the eyes of rabbits.

Glycerol Monostearate (GMS), fed to mice in doses of 50-100 mg/day or 1.5% in the diet until they died, did not induce significant brain or gastric tumor formation, respectively.
Five percent Glycerol Monostearate (GMS) did not promote the carcinogenicity of DMBA in mouse skin.
Single and Repeated Insult Patch Tests used to evaluate human skin irritation and sensitization potential of Glycerol Monostearate (GMS) and Glyceryl Stearate/SE showed both ingredients to be nonse'3ritizing and nonirritating.

Products containing 2% Glycerol Monostearate (GMS) were nonphototoxic anu ionphotoallergic.
Worker experience shows that Glycerol Monostearate (GMS) and Glyceryl Stearate/SE are nonirritating to human skin.
Glyceryl monostearate (GMS), a nonionic amphiphilic monoglyceride of glycerol and stearic acid is widely used as emulsifier in food, cosmetic, pharmaceutical and textile industry.

Glycerol Monostearate (GMS) exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.
Typically these are encountered as a mixture as many of their properties are similar.
Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol.

Uses
Glycerol Monostearate (GMS) is self-emulsifying glyceryl stearate.
Glycerol Monostearate (GMS) provides a stable, uniform oil-in-water emulsion.
Glycerol Monostearate (GMS) is used in the development of drug delivery vehicles such as nanoparticles and microemulsions.

Glycerol Monostearate (GMS) is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.
Glycerol Monostearate (GMS) is also used in cosmetics and hair-care products.
In industry, Glycerol Monostearate (GMS) can be used as an emulsifier.

Glycerol Monostearate (GMS) also occurs naturally in the body as a fat metabolite, and is present in foods with high fat content.
Glycerol Monostearate (GMS) pharmaceuticals, Glycerin monostearate is used as a protective coating for hygroscopic powders, and a solidifier and control release agen.
Glycerol Monostearate (GMS) is widely used in the food industry as an emulsifying agent to create stable mixtures of ingredients that would otherwise separate, such as oil and water.

Glycerol Monostearate (GMS) is commonly found in salad dressings, sauces, and mayonnaise.
In frozen desserts like ice cream, Glycerol Monostearate (GMS) helps prevent the crystallization of fats, improving the texture and preventing the formation of ice crystals.
Glycerol Monostearate (GMS) can thicken food products, providing a desirable texture in items like puddings, custards, and soups.

Glycerol Monostearate (GMS) is used in baked goods like bread, cakes, and cookies to improve texture, moisture retention, and shelf life.
Glycerol Monostearate (GMS) is added to dairy products such as yogurt and cream to enhance creaminess and consistency.
Glycerol Monostearate (GMS) can be found in chocolates and candies to prevent fat bloom and ensure a smooth texture.

Glycerol Monostearate (GMS) commonly known as GMS, is an organic molecule used as an emulsifier.
Glycerol Monostearate (GMS) is a colorless, odorless, and sweet-tasting flaky powder that is hygroscopic.
Glycerol Monostearate (GMS) is a glycerol ester of stearic acid.

Glycerol Monostearate (GMS) occurs naturally in the body as a by-product of the breakdown of fats, and is also found in fatty foods.
Glycerol Monostearate (GMS) is a food additive used as a thickening, emulsifying, anti-caking, and preservative agent, an emulsifying agent for oils, waxes and solvents, a
protective coating for hygroscopic powders, a solidifier and control release agent in pharmaceuticals, and a resin lubricant.
Glycerol Monostearate (GMS) is also used in cosmetics and hair care products.GMS is largely used in baking preparations to add "body" to the food.

Glycerol Monostearate (GMS) is responsible for giving ice cream and whipped cream its smooth texture.
Glycerol Monostearate (GMS) can, therefore, be used in all plastics employed for food packaging fatty amine polyglycol ethers (e.g., cocoamine + 2 EO) fatty acid diethanolamides (e.g., coconut fatty acid diethanolamide) fatty alcohol polyglycol ethers (can be used as internal antistats and viscosity modifiers in PVC plastisols or as external antistats in mold release formulations for green tires)

Glycerol Monostearate (GMS) is used as an emulsifier, resin lubricant, opacifier, emollient, bodying agent in a variety of cosmetic formulations for skincare and haircare.
Glycerol Monostearate (GMS) is also used as a thickening, anti-caking and preservative agent.
Glycerol Monostearate (GMS) is also useful for preventing ice creams from drying out or being too sweet.

Glycerol Monostearate (GMS) is further used as a foaming agent for the foam-mat drying of papaya.
Glycerol Monostearate (GMS) is also used as an anti-staling agent in bread.
Glycerol Monostearate (GMS) is used in cosmetics and personal care products, including creams, lotions, and makeup, to create stable emulsions and improve product consistency.

Glycerol Monostearate (GMS) is used as both emulsifier and stabilizer in the food industry. It is commercially available in powder or bead forms.
Glycerol Monostearate (GMS) is a food additive with a distinctive odor, white or sometimes beige in color and known in the food industry with the food code e 471.
Glycerol Monostearate (GMS) is a highly effective emulsifier in emulsifying the oil-water phase.

Glycerol Monostearate (GMS) is also effective in extending the stratification and shelf life of food products.
Glycerol Monostearate (GMS) is especially used in the bread and bakery products and pastry industry, in the oil industry.
Apart from the food industry, Glycerol Monostearate (GMS) finds use in the cosmetics, detergent, plastic and pharmaceutical industries.

Glycerol Monostearate (GMS), which is involved in the formulations of ice cream, starchy products, dairy products, chewing gum, chocolate and other food products.
Glycerol Monostearate (GMS) is used as a softener in textile products and as a lubricant in plastic products.
Glycerol Monostearate (GMS) is used as an emulsifier in ice cream, GMS prevents the development of coarse ice crystals and gives a smooth texture.

Glycerol Monostearate (GMS), which ensures the formation of stable emulsions that do not break down during freezing, improves the shelf life by keeping the ice cream firm and dry without hardening.
Glycerol Monostearate (GMS) for bakery products such as bread and cake; It causes soft, moist, good pore structure in the product, gives white shine and volume to the products, retains moisture, delays spongy structure and staleness, and increases the shelf life of the product.
With the use of Glycerol Monostearate (GMS), the amount of egg yolk used in the products decreases and thus reduces the cost.

In chocolate products, Glycerol Monostearate (GMS) provides a good oil dispersion even at high temperatures, reduces stickiness and separation during production and storage, improves texture and consistency, reduces sugar crystallization, reduces the loss of flowering and product-specific shine, prevents products such as caramel and nougat from precipitation on the tooth, It provides better dispersion and stabilization and acts as a plasticizer in chewing gums.
In margarine products, on the other hand, it reduces the tension between oil and water interfaces, which leads to the formation of stable emulsions.

When used with soy lecithin, the solubility of Glycerol Monostearate (GMS) is increased.
Glycerol Monostearate (GMS), which leads to a better mouthfeel in the product and increases its spreadability, emulsifies the water in margarine and stabilizes the water in the oil.
Glycerol Monostearate (GMS) is widely used in cosmetics.
Glycerol Monostearate (GMS) is an emulsifying and solubilizing ingredient, dispersing agent, emollient, formula stabilizer, and surface-action agent.
Employed in baby creams, face masks, foundation, and hand lotions, it is often derived from hydrogenated soybean oil.

Glycerol Monostearate (GMS) has little or no G toxicity.
Glycerol Monostearate (GMS) is prepared by the reaction of glycerin with triglycerides from animal or vegetable sources, producing a mixture of monoglycerides and diglycerides.
The diglycerides may be further reacted to produce the 90% monoglyceride grade.

Another process involves reaction of Glycerol Monostearate (GMS) with stearoyl chloride.
The starting materials are not pure substances and therefore the products obtained from the processes contain a mixture of esters, including palmitate and oleate.
Consequently, the composition, and therefore the physical properties, of Glycerol Monostearate (GMS) may vary considerably depending on the manufacturer.

The many varieties of Glycerol Monostearate (GMS) are used as nonionic emulsifiers, stabilizers, emollients, and plasticizers in a variety of food, pharmaceutical, and cosmetic applications.
Glycerol Monostearate (GMS) acts as an effective stabilizer, that is, as a mutual solvent for polar and nonpolar compounds that may form water-in-oil or oil-in-water emulsions.
Glycerol Monostearate (GMS) has moisturizing properties, making it suitable for skincare products, lip balms, and hair conditioners.

Glycerol Monostearate (GMS) can thicken formulations, providing a luxurious and creamy texture in products like body lotions and shower gels.
In pharmaceutical tablets and capsules, Glycerol Monostearate (GMS) serves as a binding agent to hold the active ingredients together and improve tablet disintegration properties.
In the manufacturing of plastics and rubber, Glycerol Monostearate (GMS) acts as a processing aid, lubricant, and antistatic agent.

Glycerol Monostearate (GMS) is used in the textile industry as a softening agent for fabrics, enhancing their texture and feel.
Glycerol Monostearate (GMS) can be incorporated into paint and coating formulations to modify rheological properties and improve spreadability.
Glycerol Monostearate (GMS) is used in candle production as a wax additive to improve burn time and candle texture.

Glycerol Monostearate (GMS) is used as a binding agent in tablet production, helping to hold the active ingredients together and improve tablet disintegration properties.
Glycerol Monostearate (GMS) is largely used in baking preparations to add "body" to the food.
Glycerol Monostearate (GMS) is somewhat responsible for giving ice cream and whipped cream their smooth texture.

Glycerol Monostearate (GMS) is sometimes used as an antistaling agent in bread.
Glycerol Monostearate (GMS) can also be used as an additive in plastic, where Glycerol Monostearate (GMS) works as an antistatic and antifogging agent.
Glycerol Monostearate (GMS) can be used in tablet coating formulations to provide a smooth and consistent coating on pharmaceutical tablets, making them easier to swallow and improving their appearance.

Glycerol Monostearate (GMS) is found in some toothpaste formulations as a thickening and stabilizing agent to provide the desired texture and consistency.
Glycerol Monostearate (GMS) is used in the pet food industry as an emulsifier and stabilizer in various pet food products, including wet and dry pet foods.
Glycerol Monostearate (GMS) can be employed in the paper industry as a paper coating additive to improve printability, reduce dusting, and enhance the paper's surface properties.

Glycerol Monostearate (GMS) can be used as a slip agent to reduce friction between layers of film and improve the film's handling and processing characteristics.
Glycerol Monostearate (GMS) may be added to adhesive formulations to improve their tackiness and adhesion properties, making them more effective in bonding various materials.
Glycerol Monostearate (GMS) can serve as a base material for suppositories in pharmaceutical applications, helping to solidify and shape the suppository for rectal administration.

Glycerol Monostearate (GMS) can be used as a component of metalworking fluids to provide lubrication and cooling properties in machining processes.
Glycerol Monostearate (GMS) may be used as a component in lubricants to reduce friction and wear in machinery.

Glycerol Monostearate (GMS) is added to shoe polish formulations to enhance the shine and water resistance of leather shoes.
Glycerol Monostearate (GMS) is used in some pyrotechnic compositions to control the burning rate of fireworks and produce specific effects.

Safety Profile:
Concentrated or prolonged contact with Glycerol Monostearate (GMS) may cause skin and eye irritation in some individuals.
Glycerol Monostearate (GMS) is advisable to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles, when handling Glycerol Monostearate (GMS) in its concentrated form.

Glycerol Monostearate (GMS) powder or dust can lead to respiratory irritation.
Adequate ventilation is important when working with powdered GMS.
Although rare, some individuals may have allergies or sensitivities to Glycerol Monostearate (GMS).

Allergic reactions could include skin rashes or other symptoms.
Glycerol Monostearate (GMS) itself is not flammable, but it can release flammable gases (siloxanes) if subjected to high temperatures or open flames.

Therefore, it should be stored away from heat sources and open flames.
To minimize hazards, follow safe handling practices, such as wearing appropriate PPE, avoiding contact with eyes and skin, and taking measures to prevent inhalation of dust or powder during handling.

Synonyms:
Glyceryl monostearate
123-94-4
Monostearin
GLYCEROL MONOSTEARATE
31566-31-1
Glyceryl stearate
Tegin
1-Stearoyl-rac-glycerol
1-MONOSTEARIN
Glycerin 1-monostearate
Stearin, 1-mono-
Stearic acid 1-monoglyceride
2,3-dihydroxypropyl octadecanoate
Glycerol 1-monostearate
1-Glyceryl stearate
Glycerin 1-stearate
Sandin EU
1-Monostearoylglycerol
Octadecanoic acid, 2,3-dihydroxypropyl ester
Aldo MSD
Aldo MSLG
Glyceryl 1-monostearate
Stearoylglycerol
Glycerol 1-stearate
alpha-Monostearin
Tegin 55G
Emerest 2407
Aldo 33
Aldo 75
Arlacel 165
3-Stearoyloxy-1,2-propanediol
Cerasynt SD
Stearin, mono-
2,3-Dihydroxypropyl stearate
.alpha.-Monostearin
Monoglyceryl stearate
Glycerol alpha-monostearate
Cefatin
Dermagine
Monelgin
Sedetine
Admul
Orbon
Citomulgan M
Drewmulse V
Cerasynt S
Drewmulse TP
Tegin 515
Cerasynt SE
Cerasynt WM
Cyclochem GMS
Drumulse AA
Protachem GMS
Witconol MS
Witconol MST
FEMA No. 2527
Glyceryl stearates
Monostearate (glyceride)
Unimate GMS
Glyceryl monooctadecanoate
Ogeen M
Emcol CA
Emcol MSK
Hodag GMS
Ogeen GRB
Ogeen MAV
Aldo MS
Aldo HMS
Armostat 801
Kessco 40
Stearic monoglyceride
Abracol S.L.G.
Arlacel 161
Arlacel 169
Imwitor 191
Imwitor 900K
NSC 3875
11099-07-3
Atmul 67
Atmul 84
Starfol GMS 450
Starfol GMS 600
Starfol GMS 900
Cerasynt 1000-D
Emerest 2401
Aldo-28
Aldo-72
Atmos 150
Atmul 124
Estol 603
Ogeen 515
Tegin 503
Grocor 5500
Grocor 6000
Glycerol stearate, pure
Stearic acid alpha-monoglyceride
Cremophor gmsk
Glyceryl 1-octadecanoate
Cerasynt-sd
Lonzest gms
Cutina gms
Lipo GMS 410
Lipo GMS 450
Lipo GMS 600
glycerol stearate
1-MONOSTEAROYL-rac-GLYCEROL
Nikkol mgs-a
Glyceryl monopalmitostearate
USAF KE-7
1-octadecanoyl-rac-glycerol
EMUL P.7
EINECS 204-664-4
EINECS 245-121-1
UNII-230OU9XXE4
Stearic acid, monoester with glycerol
Glycerol .alpha.-monostearate
Glyceroli monostearas
Glycerol monostearate, purified
Imwitor 491
Sorbon mg-100
22610-63-5
Cithrol gms 0400
UNII-258491E1RZ
NSC3875
Stearic acid .alpha.-monoglyceride
(1)-2,3-Dihydroxypropyl stearate
MONOSTEARIN (L)
C21H42O4
NSC-3875
1-Monooctadecanoylglycerol
EINECS 250-705-4
1,2,3-Propanetriol monooctadecanoate
Octadecanoic acid, ester with 1,2,3-propanetriol
GLYCERYL 1-STEARATE
1-O-Octadecanoyl-2n-glycerol
AI3-00966
MG(18:0/0:0/0:0)[rac]
230OU9XXE4
DTXSID7029160
CHEBI:75555
EC 250-705-4
GLYCERYL MONOSTEARATE 40-50
Octadecanoic acid, monoester with 1,2,3-propanetriol
258491E1RZ
1-Stearoyl-rac-glycerol (90per cent)
83138-62-9
NCGC00164529-01
(+/-)-2,3-DIHYDROXYPROPYL OCTADECANOATE
DTXCID909160
Octadecanoic acid, 2,3-dihydroxypropyl ester, (A+/-)-
MFCD00036186
Celinhol - A
CAS-123-94-4
GMS
Myvaplex 600
rac-Glycerol 1-stearate
1-Monooctadecanoyl-rac-glycerol
Celinhol-A
Glyceryl monostearate [JAN:NF]
MG 18:0
(+/-)-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
Eastman 600
1-O-stearoylglycerol
1-octadecanoylglycerol
85666-92-8
rac-octadecanoylglycerol
glycerol 1-octadecanoate
rac-glyceryl monostearate
Glycerol .alpha.-sterate
rac-1-monostearoylglycerol
DSSTox_CID_9160
Monoglycerides, c16-18
(+-)-1-stearoylglycerol
SCHEMBL4488
(+-)-glyceryl monostearate
Geleol mono and diglycerides
DSSTox_RID_78757
DSSTox_GSID_29304
Glycerol monostearate (GMS)
(+-)-1-monostearoylglycerol
(+-)-1-octadecanoylglycerol
Glycerides, C16-18 mono-
Glycerol monostearate 40-55
GLYCERYL STEARATE (II)
CHEMBL255696
2,3-Dihydroxypropyl stearate #
DTXSID7027968
CHEBI:75557
1-Stearoyl-rac-glycerol (90%)
GLYCERYL MONOSTEARATE (II)
Glyceryl monostearate (JP17/NF)
1-Stearoyl-rac-glycerol, >=99%
MAG 18:0
EINECS 238-880-5
EINECS 293-208-8
Tox21_112160
Tox21_202573
Tox21_301104
LMGL01010003
rac-2,3-dihydroxypropyl octadecanoate
AKOS015901589
Tox21_112160_1
DB11250
(+-)-2,3-dihydroxypropyl octadecanoate
NCGC00164529-02
NCGC00164529-03
NCGC00164529-04
NCGC00255004-01
NCGC00260122-01
Octadecanoic acid,3-dihydroxypropyl ester
1,2,3-Propanetriol 1-octadecanoyl ester
BS-50505
CAS-11099-07-3
FT-0626740
FT-0626748
FT-0674656
G0085
Octadecanoic acid, 2.3-dihydroxypropyl ester
D01947
EC 293-208-8
F71433
S-7950
A890632
A903419
SR-01000944874
Q-201168
Q5572563
SR-01000944874-1
W-110285
()-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
342394-34-7
InChI=1/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H

CALCIUM GLYCEROPHOSPHATE, N° CAS : 27214-00-2 / 126-95-4 / 1336-00-1 / 58409-70-4 - Glycérophosphate de calcium, Nom INCI : CALCIUM GLYCEROPHOSPHATE Nom chimique : Calcium glycerophosphate, N° EINECS/ELINCS : 248-328-5 / 204-813-3 / 215-643-4 / 261-240-1, Le glycérophosphate de calcium aussi appelé glycérophosphate de chaux, se présente sous la forme d'une poudre blanche. Il est utilisé en cosmétique dans les dentifrices en tant qu'actif anti-plaques et anti-caries, il optimise l'action des fluorures.Antiplaque : Aide à protéger contre la formation de plaque dentaire Agent d'hygiène buccale : Fournit des effets cosmétiques à la cavité buccale (nettoyage, désodorisation et protection)

DESCRIPTION:

Glycerol triacetate, is the organic compound with the formula C3H5(OCOCH3)3.
Glycerol triacetate is classified as a triglyceride, i.e., the triester of glycerol.
Glycerol triacetate is a colorless, viscous, and odorless liquid with a high boiling point and a low melting point.

CAS Number:102-76-1
EC Number: 203-051-9
IUPAC name: Propane-1,2,3-triyl triacetate
Molecular Weight: 218.20
Linear Formula: (CH3COOCH2)2CHOCOCH3


GLYCEROL TRIACETATE= TRIACETIN

CHEMICAL AND PHYSICAL PROPERTIES OF GLYCEROL TRIACETATE:
Chemical formula: C9H14O6
Molar mass: 218.205 g•mol−1
Appearance: Oily liquid
Density :1.155 g/cm3[3]
Melting point: −78 °C (−108 °F; 195 K)
at 760 mmHg
Boiling point: 259 °C (498 °F; 532 K)
at 760 mmHg
Solubility in water: 6.1 g/100 mL
Solubility: Miscible in EtOH
Soluble in C6H6, (C2H5)2O, acetone
Vapor pressure: 0.051 Pa (11.09 °C)
0.267 Pa (25.12 °C)
2.08 Pa (45.05 °C)[4]
ln(P/Pa)=22.819-4493/T(K)-807000/T(K)²
Refractive index (nD): 1.4301 (20 °C)
1.4294 (24.5 °C)
Viscosity: 23 cP (20 °C)
Thermochemistry:
Heat capacity (C): 389 J/mol•K
Std molar entropy (S⦵298): 458.3 J/mol•K
Std enthalpy of formation (ΔfH⦵298): −1330.8 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): 4211.6 kJ/mol
Assay: ≥99.0% (GC)
Form: liquid
refractive index: n20/D 1.431
bp: 258-260 °C (lit.)
Density: 1.158 g/mL at 20 °C
Molecular Weight: 218.20
XLogP3: 0.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 8
Exact Mass: 218.07903816
Monoisotopic Mass: 218.07903816
Topological Polar Surface Area: 78.9 Ų
Heavy Atom Count: 15
Formal Charge: 0
Complexity: 229
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 258 °C (1013 hPa)
Density : 1.161 g/cm3 (20 °C)
Explosion limit: 1.1 - 7.7 %(V)
Flash point: 148 °C
Ignition temperature: 430 °C
Melting Point: -78 °C
pH value: 5.0 - 6.0 (50 g/l, H₂O, 20 °C)
Vapor pressure: 0.003 hPa (25 °C)
Solubility: 64 g/l


Glycerol triacetate has a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations.
Glycerol triacetate is one of the glycerine acetate compounds.
Glycerol triacetate is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.

Glycerol triacetate has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.
Glycerol triacetate has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug.

Glycerol triacetate is functionally related to an acetic acid.
Glycerol triacetate is a natural product found in Vitis vinifera with data available.
A triglyceride that is used as an antifungal agent.
Glycerol triacetate is a triacetin compound that is used in the production of glycerol and glycerin.
The water vapor-resistant nature of this compound makes it an excellent candidate for use in projects where water vapor may be present.

Glycerol triacetate has been shown to have a high resistance to solid phase microextraction and can be used as a model system for studying the interactions of triacetates with other materials.
The reaction solution containing glycerol triacetate is acidic, which may lead to problems with water permeability if not properly treated.
This analytical method utilizes hydrogen bonding interactions between glycerol and glycerine molecules to measure the concentration of each component in the sample.

USES OF GLYCEROL TRIACETATE:
Glycerol triacetate is a common food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.
Glycerol triacetate is used as an excipient in pharmaceutical products, where it is used as a humectant, a plasticizer, and as a solvent.

POTENTIAL USES OF GLYCEROL TRIACETATE:
The plasticizing capabilities of triacetin have been utilized in the synthesis of a biodegradable phospholipid gel system for the dissemination of the cancer drug paclitaxel (PTX).
In the study, triacetin was combined with PTX, ethanol, a phospholipid and a medium chain triglyceride to form a gel-drug complex.
This complex was then injected directly into the cancer cells of glioma-bearing mice.
The gel slowly degraded and facilitated sustained release of PTX into the targeted glioma cells.

Glycerol triacetate can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.
It has been considered as a possible source of food energy in artificial food regeneration systems on long space missions.
It is believed to be safe to get over half of one's dietary energy from triacetin.

SYNTHESIS OF GLYCEROL TRIACETATE:
Glycerol triacetate was first prepared in 1854 by the French chemist Marcellin Berthelot.
Glycerol triacetate was prepared in the 19th century from glycerol and acetic acid.
Its synthesis from acetic anhydride and glycerol is simple and inexpensive.
3 (CH3CO)2O + 1 C3H5(OH)3 → 1 C3H5(OCOCH3)3 + 3 CH3CO2H

This synthesis has been conducted with catalytic sodium hydroxide and microwave irradiation to give a 99% yield of triacetin.
It has also been conducted with a cobalt(II) Salen complex catalyst supported by silicon dioxide and heated to 50 °C for 55 minutes to give a 99% yield of triacetin.

Safety:
The US Food and Drug Administration has approved it as Generally Recognized as Safe (GRAS) food additive and included it in the database according to the opinion from the Select Committee On GRAS Substances (SCOGS).
Glycerol triacetate and two types of acetooleins have been found to be without toxic effects in long-term feeding tests in rats at levels that were several orders of magnitude greater than those to which consumers are exposed.

Three types of acetostearins have been found to be without toxic effects in long-term feeding tests in rats at levels up to 5 g per kg per day.
This contrasts with an estimated human consumption of a fraction of a milligram per kg per day.
It is recognized that at an even higher feeding level (10 g per kg per day) male rats developed testicular atrophy and female rats, uterine discoloration.

However, such a level which would amount to 50 g or more for an infant and 600 g for an adult per day, is vastly higher than would be possible in the consumption of foods to which acetostearins are added for functional purposes.
Glycerol triacetate is included in the SCOGS database since 1975.

Glycerol triacetate was not toxic to animals in studies of exposure through repeated inhalation over a relatively short period.

SAFETY INFORMATION ABOUT GLYCEROL TRIACETATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



SYNONYMS OF GLYCEROL TRIACETATE:
MeSH Entry Terms:
Enzactin
Triacetin
Triacetyl glycerol
Triacetyl-glycerol
Triacetylglycerol
Depositor-Supplied Synonyms:
triacetin
102-76-1
Glyceryl triacetate
Glycerol triacetate
Enzactin
Glycerin triacetate
Triacetine
Triacetylglycerol
Fungacetin
Glyped
Triacetyl glycerine
Vanay
Kesscoflex TRA
Kodaflex triacetin
1,2,3-Propanetriol, triacetate
1,2,3-triacetoxypropane
Acetin, tri-
propane-1,2,3-triyl triacetate
1,2,3-Propanetriol, 1,2,3-triacetate
Triacetina
Triacetinum
1,2,3-Propanetriol triacetate
Triacetin [INN]
Ujostabil
Estol 1581
FEMA No. 2007
Triacetyl glycerin
Triacetyl glycerol
1,2,3-Propanetriyl triacetate
1,2,3-Triacetylglycerol
2,3-diacetyloxypropyl acetate
Glyceryltriacetate
NSC 4796
Triacetin (USP/INN)
Acetic, 1,2,3-propanetriyl ester
ENZACTIN (TN)
NSC-4796
Ins no.1518
1,2,3-triacetyl-glycerol
2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate
Ins-1518
1,2,3-triacetyl-sn-glycerol
CHEBI:9661
XHX3C3X673
E1518
E-1518
NCGC00091612-04
Triacetin (1,2,3-Propanetriol triacetate)
DSSTox_CID_6691
DSSTox_RID_78184
DSSTox_GSID_26691
FEMA Number 2007
Triacetine [INN-French]
Triacetinum [INN-Latin]
Triacetina [INN-Spanish]
CAS-102-76-1
HSDB 585
EINECS 203-051-9
TRIACETIN (GLYCEROL TRIACETATE)
BRN 1792353
Triacetin [USP:INN:BAN]
UNII-XHX3C3X673
Enzacetin
Euzactin
Fungacet
Motisil
Blekin
tri-acetin
AI3-00661
CCRIS 9355
Triacetin, CP
Triacetin, FCC
Triacetin, USP
3-Triacetoxypropane
Glycerine triacetate
MFCD00008716
Triacetin, 99%
Spectrum_000881
TRIACETIN [FCC]
TRIACETIN [II]
TRIACETIN [MI]
TRIACETIN [FHFI]
TRIACETIN [HSDB]
TRIACETIN [INCI]
Spectrum2_000939
Spectrum3_001368
Spectrum4_000362
Spectrum5_001376
TRIACETIN [VANDF]
TRIACETIN [MART.]
EC 203-051-9
Triacetin, >=99.5%
SCHEMBL3870
TRIACETIN [USP-RS]
TRIACETIN [WHO-DD]
BSPBio_002896
Glycerol triacetate tributyrin
KBioGR_000823
KBioSS_001361
4-02-00-00253 (Beilstein Handbook Reference)
MLS002152946
1,3-Propanetriol, triacetate
DivK1c_000740
Glyceryl triacetate, >=99%
SPECTRUM1500585
Triacetin, analytical standard
SPBio_000878
Triacetin, 99%, FCC, FG
1,2,3-propanediol triethanoate
CHEMBL1489254
DTXSID3026691
TRIACETIN [EP MONOGRAPH]
FEMA 2007
HMS502E22
KBio1_000740
KBio2_001361
KBio2_003929
KBio2_006497
KBio3_002116
NSC4796
TRIACETIN [USP MONOGRAPH]
NINDS_000740
HMS1921G05
HMS2092O09
HMS2232I22
Pharmakon1600-01500585
Triacetin, >=99%, natural, FG
HY-B0896
ZINC1530705
Tox21_111155
Tox21_201745
Tox21_300111
WLN: 1VO1YOV1 & 1OV1
CCG-39680
LMGL03012615
NSC757364
s4581
Triacetin, 8CI, BAN, INN, USAN
1,2,3-Propanetriol triacetate, 9CI
AKOS009028851
Tox21_111155_1
Glyceryl triacetate, >=99.0% (GC)
NSC-757364
1,3-bis(acetyloxy)propan-2-yl acetate
IDI1_000740
NCGC00091612-01
NCGC00091612-02
NCGC00091612-03
NCGC00091612-05
NCGC00091612-06
NCGC00091612-07
NCGC00091612-09
NCGC00254207-01
NCGC00259294-01
LS-13668
SMR001224538
SBI-0051540.P002
FT-0626753
G0086
EN300-19216
D00384
E 1518
E75962
Q83253
AB00052112_06
A800614
SR-05000002079
J-000781
SR-05000002079-1
2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate #
Z104473192
Triacetin, GTA F.G (1,2,3-PROPANETRIOL TRIACETATE)
Triacetin, United States Pharmacopeia (USP) Reference Standard
Triacetin, Pharmaceutical Secondary Standard; Certified Reference Material
1,2,3-Propanetriol triacetate; Glycerol Triacetate, USP Grade(1.03000); TRIACETINE; Glycerol triacetate; Glyceryl triacetate; propane-1,2,3-triyl triacetate

Glycerol triacetate is a clear, viscous liquid with a sweet and fruity odor.
Glycerol triacetate is a colorless to pale yellow compound.
Glycerol triacetate has a molecular weight of approximately 218.21 grams per mole.

CAS Number: 102-76-1
EC Number: 203-051-9



APPLICATIONS


Glycerol triacetate is commonly used as a food additive and flavoring agent in the food industry.
Glycerol triacetate is employed as a solvent and excipient in pharmaceutical formulations.
Glycerol triacetate finds application in the production of confectionery items, providing enhanced flavor and mouthfeel.
Glycerol triacetate serves as a plasticizer in the manufacturing of plastics and films, improving their flexibility and durability.

Glycerol triacetate is utilized in the printing industry for the formulation of inks, improving ink flow and print quality.
Glycerol triacetate is used in the cosmetics industry as an emollient and fragrance enhancer in various personal care products.
Glycerol triacetate acts as a humectant in tobacco products, maintaining moisture levels and enhancing flavor.

Glycerol triacetate finds application in the production of adhesives and sealants, improving flexibility and adhesion properties.
Glycerol triacetate is used in the textile industry as a softening agent and lubricant for fibers and fabrics.
Glycerol triacetate serves as a solvent for various chemical reactions and experiments in laboratory settings.
Glycerol triacetate is employed in the agricultural industry as a formulation component in pesticides and herbicides.

Glycerol triacetate is used as a biodiesel additive, improving the performance and stability of biodiesel fuels.
Glycerol triacetate finds application in the leather industry as a softening agent and lubricant for leather processing.
Glycerol triacetate is utilized in metalworking fluids, improving lubricity and reducing friction during machining.

Glycerol triacetate serves as a coalescing agent in water-based coatings, aiding in film formation and performance.
Glycerol triacetate is used as a formulation component in insecticides and repellents in the pest control industry.
Glycerol triacetate finds application in the production of electrical capacitors and electronic components.
Glycerol triacetate is employed in metal plating processes as a leveling agent and brightener.

Glycerol triacetate can be used as a dielectric fluid or insulating material in electrical applications.
Glycerol triacetate is utilized in fuel cells as an electrolyte additive to enhance conductivity.
Glycerol triacetate finds application in gas chromatography as a reference standard or calibration compound.
Glycerol triacetate is used in smoke generators for special effects in theatrical productions or training simulations.

Glycerol triacetate serves as a solvent for resins, polymers, and cellulose derivatives in various applications.
Glycerol triacetate finds use in the inkjet printing industry for the formulation of stable inks.
Glycerol triacetate can be used as a solvent for cleaning and degreasing applications in automotive and manufacturing industries.


Some of its common applications include:

Food Industry:
Glycerol triacetate is used as a food additive and flavoring agent.
Glycerol triacetate enhances the taste and aroma of various food products, including confectionery, baked goods, beverages, and dairy products.

Pharmaceutical Industry:
Glycerol triacetate is utilized as a solvent and excipient in pharmaceutical formulations.
Glycerol triacetate helps improve the solubility and stability of active pharmaceutical ingredients in oral and topical medications.

Cosmetic and Personal Care Products:
Glycerol triacetate finds application in cosmetics and personal care products as a solvent, emollient, and fragrance enhancer.
Glycerol triacetate is used in items like lotions, creams, perfumes, and hair care products.

Plastics and Packaging:
Glycerol triacetate acts as a plasticizer in the production of plastics, films, and coatings.
Glycerol triacetate enhances flexibility, durability, and transparency in various plastic materials.

Printing Inks:
Glycerol triacetate is used in the formulation of printing inks, including those for flexographic and gravure printing.
Glycerol triacetate helps control ink viscosity and enhances ink transfer properties.

Tobacco Industry:
Glycerol triacetate is employed as a humectant and plasticizer in tobacco products, such as cigarettes and cigars.
Glycerol triacetate helps maintain moisture levels, enhance flavor, and improve the burning characteristics of tobacco.

Industrial Applications:
Glycerol triacetate serves as a solvent and intermediate in various industrial processes.
Glycerol triacetate is used in the production of adhesives, sealants, coatings, and lubricants.

Textile Industry:
Glycerol triacetate finds application in the textile industry as a softening agent and lubricant for fibers, yarns, and fabrics.
Glycerol triacetate helps improve the flexibility and handling of textile materials.

Specialty Chemicals:
Glycerol triacetate is used as a raw material for the synthesis of other chemicals and esters.
Glycerol triacetate serves as an important intermediate in the production of fragrances, flavors, and pharmaceutical ingredients.

Adhesives and Sealants:
Glycerol triacetate is used as a plasticizer and solvent in the formulation of adhesives and sealants.
Glycerol triacetate helps improve the flexibility and adhesion properties of these products.

Agricultural Industry:
Glycerol triacetate is used as a formulation component in agricultural products such as pesticides, herbicides, and insecticides.
Glycerol triacetate can aid in improving the stability and efficacy of these formulations.

Fuel and Energy:
Glycerol triacetate is utilized as a biodiesel additive and fuel oxygenate.
Glycerol triacetate can enhance the performance and stability of biodiesel fuels.

Leather Industry:
Glycerol triacetate finds application in the leather industry as a softening agent and lubricant for leather processing.
Glycerol triacetate helps improve the pliability and durability of leather goods.

Metalworking Fluids:
Glycerol triacetate is added to metalworking fluids, such as cutting oils and coolants, to improve lubricity and reduce friction during machining operations.

Water-based Coatings:
Glycerol triacetate can be used as a coalescing agent in water-based coatings and paints.
Glycerol triacetate aids in film formation and enhances the performance of these coatings.

Smoke Generation:
Glycerol triacetate is sometimes used in smoke generators for special effects, such as theatrical productions or training simulations.

Solvent for Resins and Polymers:
Glycerol triacetate serves as a solvent for various resins, polymers, and cellulose derivatives.
Glycerol triacetate helps dissolve these materials and facilitates their processing.

Electrical and Electronics Industry:
Glycerol triacetate is utilized in the manufacturing of electrical capacitors and electronic components as a dielectric fluid or insulating material.

Metal Plating:
Glycerol triacetate is employed in electroplating processes as a leveling agent and brightener for metal coatings.

Fuel Cell Electrolyte:
Glycerol triacetate is used as an electrolyte additive in fuel cells to enhance the performance and conductivity of the electrolyte solution.

Gas Chromatography:
Glycerol triacetate can be used as a reference standard or calibration compound in gas chromatography analysis.

Inkjet Printing:
Glycerol triacetate is utilized in the formulation of inks for inkjet printers, providing improved stability and ink flow characteristics.

Cleaning and Degreasing:
Glycerol triacetate can be used as a solvent for cleaning and degreasing applications, particularly in industries such as automotive and manufacturing.

Water Treatment:
Glycerol triacetate may be used in water treatment processes as a dispersant or solvent for certain chemicals or contaminants.



DESCRIPTION


Glycerol triacetate is a clear, viscous liquid with a sweet and fruity odor.
Glycerol triacetate is a colorless to pale yellow compound.
Glycerol triacetate has a molecular weight of approximately 218.21 grams per mole.

Glycerol triacetate is soluble in many organic solvents but has limited solubility in water.
Glycerol triacetate has a boiling point of around 258 degrees Celsius.

Glycerol triacetate is derived from the esterification of glycerol with acetic acid.
Glycerol triacetate is commonly used as a food additive, primarily as a flavoring agent and solvent.
Glycerol triacetate is considered safe for consumption in regulated quantities.

Glycerol triacetate is known for its ability to enhance the aroma and taste of food products.
Glycerol triacetate is used in the production of confectionery, baked goods, and beverages.

Glycerol triacetate acts as a plasticizer in the manufacturing of plastics, films, and coatings.
Glycerol triacetate exhibits low volatility, making it suitable for various applications.
Glycerol triacetate is often employed as a solvent in the pharmaceutical and cosmetic industries.
Glycerol triacetate is used in the production of printing inks and dyes.

Glycerol triacetate is compatible with a wide range of materials, including cellulose derivatives and resins.
Glycerol triacetate is known for its stability and resistance to oxidation and discoloration.
Glycerol triacetate has a relatively low freezing point, making it useful in low-temperature applications.
Glycerol triacetate can act as a viscosity modifier and lubricant.

Glycerol triacetate is often utilized as a humectant to retain moisture in products.
Glycerol triacetate is biodegradable and has low toxicity.
Glycerol triacetate is subject to regulatory guidelines and specifications regarding its use in various industries.

Glycerol triacetate may undergo hydrolysis under certain conditions, releasing acetic acid and glycerol.
Glycerol triacetate is stable under normal storage and handling conditions.
Glycerol triacetate has a wide range of applications in the food, pharmaceutical, and chemical industries.
Glycerol triacetate is recognized for its versatility, combining desirable properties as a solvent, plasticizer, and flavor enhancer.

Glycerol triacetate, also known as triacetin or triacetyl glycerol, is a chemical compound with the molecular formula C9H14O6.
Glycerol triacetate is an ester derived from glycerol and acetic acid.
Glycerol triacetate is a clear, colorless to pale yellow liquid with a slightly sweet odor.
Glycerol triacetate is commonly used as a food additive, a plasticizer, and a solvent in various industries.



PROPERTIES


Physical Properties:

Molecular Formula: C9H14O6
Molecular Weight: 218.21 g/mol
Appearance: Clear, colorless to pale yellow liquid
Odor: Slightly sweet and fruity odor
Density: 1.16 g/cm³
Boiling Point: Approximately 258 °C (496 °F)
Melting Point: -78 °C (-108.4 °F)
Solubility: Soluble in many organic solvents; limited solubility in water
Viscosity: High viscosity liquid
Refractive Index: 1.433 (at 20 °C)


Chemical Properties:

Glycerol triacetate is an ester derived from glycerol and acetic acid.
It undergoes esterification, forming three acetyl groups on the glycerol molecule.
The compound is stable under normal storage and handling conditions.
Glycerol triacetate is relatively resistant to oxidation and does not easily undergo discoloration.
It can undergo hydrolysis under certain conditions, breaking down into glycerol and acetic acid.
The compound is combustible and may emit acrid smoke and fumes when heated to decomposition.
Glycerol triacetate has low toxicity and is considered safe for specific applications and regulated quantities.



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
If breathing difficulties persist, seek medical attention.
Provide artificial respiration if the person is not breathing.


Skin Contact:

Remove contaminated clothing and footwear.
Wash the affected area gently with mild soap and water for at least 15 minutes.
If irritation or redness develops, seek medical advice.
In case of chemical burns or extensive exposure, seek immediate medical attention.


Eye Contact:

Rinse the eyes immediately and thoroughly with gently flowing water for at least 15 minutes, ensuring to remove any contact lenses.
Keep the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if there are no immediate symptoms.


Ingestion:

Rinse the mouth thoroughly with water.
Do not induce vomiting unless instructed to do so by medical professionals.
Seek immediate medical attention or contact a poison control center.
Do not give anything by mouth to an unconscious person.


General First Aid:

Ensure that the affected person is taken to a well-ventilated area.
Keep the person calm and provide reassurance.
If the person is unconscious, lay them in the recovery position and seek medical attention immediately.
In all cases of exposure, whether through inhalation, skin contact, eye contact, or ingestion, it is important to seek medical advice or consult a healthcare professional for further evaluation and treatment.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles, and protective clothing, to minimize skin and eye contact.

Ventilation:
Ensure adequate ventilation in the working area to prevent the buildup of vapors.

Avoid Ingestion:
Do not eat, drink, or smoke while handling Glycerol triacetate.

Prevent Inhalation:
Avoid inhaling vapors or mists.
Use local exhaust ventilation or respiratory protection if necessary.

Spill Management:
In case of spills, contain and absorb the material with an inert absorbent.
Avoid spreading the material or allowing it to enter drains or waterways.

Grounding and Bonding:
Use appropriate grounding and bonding techniques to prevent the buildup of static charges, as Glycerol triacetate is flammable.

Handling Equipment:
Use suitable equipment, such as pumps or closed systems, to transfer or handle Glycerol triacetate safely.

Avoid High Temperatures:
Store and handle the compound away from heat sources, open flames, and high temperatures to prevent ignition or decomposition.

Separate from Incompatible Materials:
Store Glycerol triacetate away from strong oxidizing agents, acids, and alkalis to prevent reactive hazards.

Labeling:
Ensure proper labeling of containers with the name of the substance and appropriate hazard warnings.


Storage:

Containers:
Store Glycerol triacetate in tightly sealed containers made of compatible materials, such as stainless steel, glass, or high-density polyethylene (HDPE).

Temperature:
Keep storage temperatures below 40°C (104°F) to maintain stability and prevent decomposition.

Ventilation:
Provide adequate ventilation in storage areas to prevent the buildup of vapors.

Fire Safety:
Store away from ignition sources and flammable materials. Follow local fire codes and regulations.

Sunlight Exposure:
Protect containers from direct sunlight or UV radiation, as it may degrade the compound over time.

Segregation:
Store Glycerol triacetate away from incompatible substances to prevent cross-contamination or reactive hazards.

Spill Containment:
Implement measures to contain spills, such as bunding or secondary containment, to prevent environmental contamination.

Storage Stability:
Follow recommended shelf-life guidelines and storage conditions provided by the manufacturer.

Accessibility:
Store Glycerol triacetate in a secure area, out of reach of unauthorized personnel, children, or animals.

Inventory Management:
Keep an inventory of stored quantities and conduct regular inspections to ensure proper storage conditions and identify any signs of deterioration or leakage.



SYNONYMS


Acetylated glycerol
Glycerin triacetate
Glyceryl triacetate
Triacetyl glycerol
Triacetin
Triacetate of glycerol
Glyceryl triacetate ester
Glycerol triacetic acid ester
Glycerol triacetyl ester
E1518 (E number)
TAA (abbreviation for Triacetin Acetate)
Acetyl glyceryl triester
Triacetate glycerin
Glycerol acetate triester
1,2,3-triacetoxypropane
Glycerin acetic acid ester
Glycerol acetate ester
Acetic acid glycerol ester
Triacetate of glycerin
Triacetate of glycerine
Acetin
Triglycol acetate
Glycerol triacetate ester
Glyceryl triacetic ester
Acetic acid triester of glycerol
Glycerol triethanoate
Triacetylglycerol
Glyceryl triethanoate
Glycerol acetate triester
Triacetin glyceryl ester
Acetyl glycerin triester
Acetic acid triester of glycerin
Glycerin triacetic acid ester
Glyceryl acetic acid ester
Acetylated glycerin
Glyceryl triacetyl ester
Triacetate glycerin
Glycerol acetate ester
Glycerin acetic acid ester
Acetic acid glycerin ester
Glyceryl acetyl ester
Glycerol triacetic ester
Triacetin glycerol ester
Triacetate of glycerine
Glycerol triacetate acetate
Glycerol triacetate ester
Acetic acid triester of glycerol
Triacetate of glycerol
Glycerol acetate triester
Acetylated glyceryl ester
Glyceryl triacetic ester
Glycerin triacetyl ester
Triacetate of glycerine
Acetin glycerol ester
Triacetyl glycerol
Triacetyl glycerine
Acetylated glyceryl triester
Acetic acid ester of glycerol
Triacetate of glyceric acid
Glycerol acetic acid ester
Glyceryl triethanoic ester
Acetyl glyceryl triethanoate
Glycerin triacetic acid ester
Triacetate of glyceric acid
Acetylated glycerol triester
Glycerol acetyl ester
Glycerin triacetyl ester
Acetylated glycerol acetate
Glycerol triacetyl acetate
Triacetin glyceryl acetate
Glycerol triethanoic acid ester
Acetyl glycerin triethanoate
Glycerin triacetyl acetate
Triacetate of glyceryl acetate
Glycerol triethanoic ester

Glycerol triacetate (triacetin) has a very faint, fruity odor.
Glycerol triacetate (triacetin) has a mild, sweet taste that is bitter above 0.05%.


CAS Number: 102-76-1
EC Number: 203-051-9
MDL number: MFCD00008716
E number: E1518 (additional chemicals)
Linear Formula: (CH3COOCH2)2CHOCOCH3
Molecular Formula: C9H14O6 / C3H5(OCOCH3)3


Glycerol triacetate (triacetin) is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.
Glycerol triacetate (triacetin) is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
Glycerol triacetate (triacetin) derives from an acetic acid.


Glycerol triacetate (triacetin) has a very faint, fruity odor.
Glycerol triacetate (triacetin) has a mild, sweet taste that is bitter above 0.05%.
Glycerol triacetate (triacetin) is a colorless liquid; slight fatty odor; bitter taste.


Glycerol triacetate (triacetin) is slightly soluble in water; very soluble in alcohol, ether, and other organicsolvents.
Glycerol triacetate (triacetin) is a colorless, viscous liquid with a slightly fatty odor.
Glycerol triacetate (triacetin) is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.


Glycerol triacetate (triacetin) is an organic compound with the formula C3H5(OCOCH3)3.
Glycerol triacetate (triacetin) is a colorless, oily substance with a faint greasy smell.
Its high solvency power and low volatility makes Glycerol triacetate (triacetin) a good solvent and fixative for many flavors and fragrances.


Glycerol triacetate (triacetin) is obtained from acetic acid and glycerol.
Glycerol triacetate (triacetin) is more generally known as glycerin triacetate.
Glycerol triacetate (triacetin) is the triester of glycerol and acetic acid.


Glycerol triacetate (triacetin) is an artificial chemical compound, commonly used as a food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.
Glycerol triacetate (triacetin) is also a component of casting liquor with TG.


In a 1994 report released by five top cigarette companies, Glycerol triacetate (triacetin) was listed as one of the 599 cigarette additives.
The Glycerol triacetate (triacetin) is applied to the filter as a plasticizer.
Because Glycerol triacetate (triacetin) is in some sense the simplest possible fat, it is being considered a possible source of food energy in artificial food regeneration systems on long space missions.


Glycerol triacetate (triacetin) has fungistatic properties (based on release of acetic acid) and has been used in the topic.
Glycerol triacetate (triacetin) is a good solubilizer for insoluble ingredients and a fragrance fixative or carrier in perfume.
Glycerol triacetate (triacetin) has low volatility and color, high solvent power, and low toxicity.


It is believed to be safe to get over half of one's dietary energy from Glycerol triacetate (triacetin).
Glycerol triacetate (triacetin) is commercially prepared from acetic acid and glycerol.
Glycerol triacetate (triacetin) is non-toxic and non-irritating.


Glycerol triacetate (triacetin), CAS No.102-76-1, food emulsifier, manufacturing process through chemical synthesis from glycerol and Acetic Acid, available as Clear transparent oily liquid.
Glycerol triacetate (triacetin), also known as glyceryl triacetate, is pharmaceutical excipient used in manufacturing of capsules and tablets.


Glycerol triacetate (triacetin) is a colorless, oily substance with a faint greasy smell.
The triglyceride 1,2,3-triacetoxypropane is more generally known as Glycerol triacetate (triacetin) and glycerin triacetate.
Glycerol triacetate (triacetin) is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.


Glycerol triacetate (triacetin) is a triester of glycerin and acetic acid, a food-grade ingredient used as a solvent and carrier in pharmaceutical preparations and as a solvent and fixative in the compounding of perfumes and flavors.
Glycerol triacetate (triacetin) is a triester formed by the combination of glycerol and acetic acid.


This colorless, odorless, and hygroscopic liquid, Glycerol triacetate (triacetin), possesses a pleasant sweet taste.
Glycerol triacetate (triacetin) finds extensive use as a plasticizer and solvent across various applications, including the food, pharmaceutical, and cosmetic industries.


Glycerol triacetate (triacetin) is a colorless, oily liquid of slight fatty odor and bitter taste.
Glycerol triacetate (triacetin) is soluble with water and is miscible with alcohol and ether.
Glycerol triacetate (triacetin) functions in foods as a humectant and solvent.


Glycerol triacetate (triacetin) is a colourless, viscous and odorless liquid with a high boiling point.
Glycerol triacetate (triacetin) was first prepared in 1854 by the French chemist Marcellin Berthelot.
Glycerol triacetate (triacetin) is a glyceryl triacetate.


Glycerol triacetate (triacetin) acts as a plasticizer.
Glycerol triacetate (triacetin) is a clear liquid, free of suspended matter with a slight odor.
Its high solvency power and low volatility makes Glycerol triacetate (triacetin) a good solvent and fixative for many flavors and fragrances.


Glycerol triacetate (triacetin) is the organic compound with the formula C3H5(OCOCH3)3.
Glycerol triacetate (triacetin) is classified as a triglyceride, i.e., the triester of glycerol with acetic acid.
Glycerol triacetate (triacetin) is a colorless, viscous, and odorless liquid with a high boiling point and a low melting point.


Glycerol triacetate (triacetin) is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
Glycerol triacetate (triacetin) is a triester of glycerin and acetic acid that occurs naturally in papaya.
The United States Food and Drug Administration affirmed Glycerol triacetate (triacetin) as generally recognized as safe (GRAS) for use in human food.


Glycerol triacetate (triacetin) is also generally recognized as safe in animal feeds, as a pesticide adjuvant, and in food packaging.
Glycerol triacetate (triacetin) is a liquid, and has been approved by the FDA as a food additive.
Glycerol triacetate (triacetin) is a water-soluble short-chain triglyceride that may also have a role as a parenteral nutrient according to animal studies.


Glycerol triacetate (triacetin) is listed on the FDA Generally Regarded As Safe (GRAS) List.
Glycerol triacetate (triacetin) is a triacetin compound that is used in the production of glycerol and glycerin.
The water vapor-resistant nature of Glycerol triacetate (triacetin) makes it an excellent candidate for use in projects where water vapor may be present.


Glycerol triacetate (triacetin) has a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations.
Glycerol triacetate (triacetin) is one of the glycerine acetate compounds.
Glycerol triacetate (triacetin) is a natural product found in Vitis vinifera with data available.


Glycerol triacetate (triacetin) is a triglyceride that is used as an antifungal agent.
Glycerol triacetate (triacetin) is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
Glycerol triacetate (triacetin) has been considered as a possible source of food energy in artificial food regeneration systems on long space missions.


It is believed to be safe to get over half of one's dietary energy from Glycerol triacetate (triacetin).
Glycerol triacetate (triacetin) is an organic compound with the formula C3H5(OCOCH3)3.
Glycerol triacetate (triacetin) is classified as a triglyceride, i.e., the triester of glycerol.


Glycerol triacetate (triacetin) is a colorless, viscous, and odorless liquid with a high boiling point and a low melting point.
Glycerol triacetate (triacetin) has a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations


Glycerol triacetate (triacetin) is also known as triacetin, and it appears as a clear colorless oily liquid.
Glycerol triacetate (triacetin) is a trihydric alcohol; the term “glycerol” generally applies only to the pure chemical compound 1,2,3-propanetriol, while the term “glycerine” applies to the purified commercial products normally containing more than 99,5% of glycerol.


Glycerol triacetate (triacetin) is one of the glycerine acetate compounds
Glycerol triacetate (triacetin) is the triester of glycerol.
Glycerol triacetate (triacetin) is a colorless, viscous and odorless liquid at room temperature.
Glycerol triacetate (triacetin) is a colorless, oily liquids with a sweet, creamy and fruity taste.


Glycerol triacetate (triacetin) is a natural ingredient from papayas.
Glycerol triacetate (triacetin) is also a Fungicide and a fragrance and flavor solvent.
Glycerol triacetate (triacetin) is affirmed by US FDA as GRAS(generally recognized as safe) and widely accepted as safe food additive in many countries with E number E1518.


Glycerol triacetate (triacetin) is a short-chain triglyceride, also known as glyceryl triacetate, which is obtained by a chemical process of acetylation of the three hydroxy groups of glycerol.
Glyceryl triacetate, also known as triacetin, is the triester of glycerol and acetic acid.


Glycerol triacetate (triacetin) is a synthetic compound that produces a clear, combustible, and oily liquid with a bitter taste that is used as a food additive with E number E1518.
Glycerol triacetate (triacetin) is slightly soluble in water but very soluble in ether or alcohol.


Glycerol triacetate (triacetin) is a glycerin triacetate molecule.
Glycerol triacetate (triacetin) is a triglyceride, triester of glycerol, food additive with E number E1518.
The triglyceride 1,2,3-triacetoxypropane is more generally known as triacetin and glycerin triacetate.


Glycerol triacetate (triacetin) is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.
Glycerol triacetate (triacetin) is a colorless, viscous and odorless liquid.
Glycerol triacetate (triacetin) is an artificial chemical compound, commonly used as a food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.



USES and APPLICATIONS of GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) is a triester of glycerin and acetic acid, a food-grade ingredient used as a solvent and carrier in pharmaceutical preparations and as a solvent and fixative in the compounding of perfumes and flavors.
Glycerol triacetate (triacetin) also serves as an ingredient in inks for printing on plastics and other nonabsorbent surfaces.


In nature, Glycerol triacetate (triacetin) is found in wine grapes and approved by FDA as a food additive.
Glycerol triacetate (triacetin) is easily hydrolyzed, releasing free acetic acid.
Processes requiring in situ generation of acid, such as textile dyeing, can utilize Glycerol triacetate (triacetin).


In skin care preparations, Glycerol triacetate (triacetin) exhibits fungistatic properties thanks to acetic acid released after hydrolysis.
Glycerol triacetate (triacetin) is used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.


The most important use of Glycerol triacetate (triacetin) is as a plasticizer for cigarette filters.
Glycerol triacetate (triacetin) can be used as a plasticizer and solvent for acetate fiber and nitrocellulose.
Glycerol triacetate (triacetin) is also used for natural rubber and synthetic rubber.


Glycerol triacetate (triacetin) is used plasticizing and does not affect vulcanization operations.
In the Food Industry: Glycerol triacetate (triacetin) has low toxicity and can be used as a mild fungicide for vegetables, fruits, animal glue and synthetic glue, and as a food additive, it can increase by 75% in volume.


In the Daily Chemical Industry: Glycerol triacetate (triacetin) can be used as a fixative and a moisturizing base for cosmetics, and can also be formulated into a non-alkaline and chlorine-free household bleach.
As a Gasoline Additive: Glycerol triacetate (triacetin) can reduce the amount of lead discharged in the air.


As an Additive to Anti-corrosion Materials: Glycerol triacetate (triacetin) has excellent corrosion resistance to hydrocarbons.
In the Printing and Dyeing Industry: Glycerol triacetate (triacetin) can be used as a swelling agent and stabilizer for cellulose acetate;Ink, cellulose, film and some alkaline solvents are also used as plasticizers for synthetic plastic films.


Glycerol triacetate (triacetin) can be used in Food, Beverage, Pharmaceutical, Health & Personal care products, Agriculture/Animal Feed/Poultry.
Food grade Glycerol triacetate (triacetin) used in manufacturing of capsules and tablets, used as a humectant, plasticizer, and solvent.
Glycerol triacetate (triacetin) is used in Tobacco industry, Dairy food, hard candy, butter and beverage, Chewing gum, Bakes food.


In skin and hair care applications Glycerol triacetate (triacetin) can be used as an antimicrobial agent, film forming, hair dyeing, plasticizer, or a solvent that is also compatible with cellulose.
Glycerol triacetate (triacetin) has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.


Glycerol triacetate (triacetin) has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug.
Glycerol triacetate (triacetin) is a triglyceride that is used as an antifungal agent.


Glycerol triacetate (triacetin) is used as cellulose plasticizer for cigarette filters; in binders for solid rocket fuels; as fixative in perfumes; to make cosmetics and pharmaceuticals.
Glycerol triacetate (triacetin) is used as solvent for celluloid and photographic films; to remove carbon dioxide from natural gas; and as topical antifungal medication.


In Food: Glycerol triacetate (triacetin) can be used as humectant, emlusifier, binder in food such as in baked goods, beverages, chewing gum, flavoring agents, dairy desserts, cheese, processed fruit, dried vegetables, confectionery.
In Beverage: Glycerol triacetate (triacetin) can be used as emulsifier, flavor enhancer in beverage.


In Pharmaceutical: Glycerol triacetate (triacetin) can be used as an excipient in pharmaceutical products, where it is used as a humectant, a plasticizer, and as a solvent in Pharmaceutical.
In Agriculture/Animal Feed/Poultry feed: Glycerol triacetate (triacetin) can be used as feed ingredients in agriculture/animal feed/poultry feed.


Glycerol triacetate (triacetin) is used as core sand binder in metal foundry sector.
Glycerol triacetate (triacetin) is used as solvent in printing inks.
Glycerol triacetate (triacetin) is used as a highly effective plasticizer for cellulose-based plastics.


Glycerol triacetate (triacetin) is used as solvent in building wall coating.
Mostly, Glycerol triacetate (triacetin) is used in the food and cosmetics industry.
Here Glycerol triacetate (triacetin) can be found in chewing gum as a softener or as a flavor carrier.


Glycerol triacetate (triacetin) as an antimicrobial effect which is why it is used as an emollient and as a humectant.
Within the European Union Glycerol triacetate (triacetin) is allowed to be added to food solely in chewing gum and as a flavor carrier.
Glycerol triacetate (triacetin) can be identified by its e-number (E1518).


Technical Glycerol triacetate (triacetin) (mixture of mono-, di-, and small quantities of triacetin) used as a solvent for basic dyes (especially indulines) and tannin in dyeing.
Glycerol triacetate (triacetin) is used in cigarette filters.


Glycerol triacetate (triacetin) is used skin sensitization reported in a worker at a cigarette manufacturing plant.
Glycerol triacetate (triacetin) is used as chromatographic fixative, solvent, toughening agent and fragrance fixative.
Glycerol triacetate (triacetin) is used as plasticizer and fragrance fixative, ink solvent.


Glycerol triacetate (triacetin) is also used in the synthesis of medicine and dyes; humectant; carrier solvent; plasticizer; natural gas absorb carbon dioxide.
Glycerol triacetate (triacetin) is allowed to be used in spices.


Glycerol triacetate (triacetin) is used food additive as a solvent for other additives, especially flavors.
Glycerol triacetate (triacetin) can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.


Glycerol triacetate (triacetin), also known as glyceryl triacetate, is pharmaceutical excipient used in manufacturing of capsules and tablets.
Glycerol triacetate (triacetin) is also used as a humectant, plasticizer, and solvent.
Glycerol triacetate (triacetin) is also used in the food, perfume and cosmetic industries.


Glycerol triacetate (triacetin) is used as a carrier, solvent or as a wetting agent.
Glycerol triacetate (triacetin) is added to chewing gum, alcoholic and non-alcoholic beverages, food additives.
In addition to food, Glycerol triacetate (triacetin) is added to toothpaste, hair dyes, cigarette filters or perfumes.


Glycerol triacetate (triacetin) is used as a binder for solid rocket fuels.
Glycerol triacetate (triacetin) is used Fungicide, humectant and solvent for flavours derived from glycerol and acetic acid.
Glycerol triacetate (triacetin) can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of bio diesel.


Glycerol triacetate (triacetin) is used as spice fixative, solvent, toughening agent.
Glycerol triacetate (triacetin) is used in the production of cosmetics, medicines and dyes, as a plasticizer for cigarette filter rods, etc.
Glycerol triacetate (triacetin) is used Substrate for determination of lipase, fragrance fixative.


Glycerol triacetate (triacetin) is used as fixative in perfumery; solvent in manufacture of celluloid, photographic films.
Technical Glycerol triacetate (triacetin) (a mixture of mono-, di-, and small quantities of triacetin) as a solvent for basic dyes, particularly indulines, and tannin in dyeing.


Glycerol triacetate (triacetin) is also a component of casting liquor with TG and as an excipient in pharmaceutical products where it is used as a humectant, a plasticiser, and as a solvent.
Glycerol triacetate (triacetin) is used to coat fresh fruit in the US, essences, cigarette filters, as a solvent in flavourings, and for its humectant function.


Glycerol triacetate (triacetin) is used in chewing gum and other food contact related plastic compound.
Glycerol triacetate (triacetin) has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.


Glycerol triacetate (triacetin) has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug.
Glycerol triacetate (triacetin) is also used for natural rubber and synthetic rubber.


Glycerol triacetate (triacetin) is functionally related to an acetic acid.
Glycerol triacetate (triacetin) is a common food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.


Glycerol triacetate (triacetin) is used as an excipient in pharmaceutical products, where it is used as a humectant, a plasticizer, and as a solvent.
The plasticizing capabilities of Glycerol triacetate (triacetin) have been utilized in the synthesis of a biodegradable phospholipid gel system for the dissemination of the cancer drug paclitaxel (PTX).


Glycerol triacetate (triacetin) has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.
Glycerol triacetate (triacetin) is mainly used as a synthetic flavoring agent in ice-creams, nonalcoholic beverages and baked goods.


Glycerol triacetate (triacetin) is used as plasticizer.
Glycerol triacetate (triacetin) is used as curing agent.
Glycerol triacetate (triacetin) is used as fragrance fixing agent.


Glycerol triacetate (triacetin) is used as fiber solvent.
The most important use of Glycerol triacetate (triacetin) is as a plasticizer for cigarette filters.
Glycerol triacetate (triacetin) can be used as a plasticizer and solvent for acetate fiber and nitrocellulose.


In the study, Glycerol triacetate (triacetin) was combined with PTX, ethanol, a phospholipid and a medium chain triglyceride to form a gel-drug complex.
Glycerol triacetate (triacetin) was then injected directly into the cancer cells of glioma-bearing mice.
Glycerol triacetate (triacetin) slowly degraded and facilitated sustained release of PTX into the targeted glioma cells.


Glycerol triacetate (triacetin) can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.
Glycerol triacetate (triacetin) is used Solvent for flavors & fragrance, Cosmetic fixative, Food additive (E1518), Plasticizer in chewing gu, and Plasticizer for cigarette filter tips.


Glycerol triacetate (triacetin) is used in ink coating, cellulose nitrate, cellulose acetate, ethyl cellulose and cellulose acetate butyrate plasticizer and solvent, and Plasticizer and curing agent in foundry resins.
Glycerol triacetate (triacetin) is used primarily for flavors and extracts, as well as chewing pastes.


Glycerol triacetate (triacetin) is used Softening agents in thickeners.
Since Glycerol triacetate (triacetin) also has a moisturizing effect, it is used as a plasticizer for plastics and as a solubilizer for paint, textile, paper and leather treatment agents.


Glycerol triacetate (triacetin) is plasticizing and does not affect vulcanization operations.
In the Food Industry: Glycerol triacetate (triacetin) has low toxicity and can be used as a mild fungicide for vegetables, fruits, animal glue and synthetic glue, and as a food additive, it can increase by 75% in volume.


In the Daily Chemical Industry: Glycerol triacetate (triacetin) can be used as a fixative and a moisturizing base for cosmetics, and can also be formulated into a non-alkaline and chlorine-free household bleach.
As a Gasoline Additive: Glycerol triacetate (triacetin) can reduce the amount of lead discharged in the air.


As an Additive to Anti-corrosion Materials: Glycerol triacetate (triacetin) has excellent corrosion resistance to hydrocarbons.
In the Printing and Dyeing Industry: Glycerol triacetate (triacetin) can be used as a swelling agent and stabilizer for cellulose.
Glycerol triacetate (triacetin) is also widely employed in laboratory settings as a buffer, stabilizer, or solvent.


Both substances are readily absorbed, broken down and used calorically by the body.
Glycerol triacetate (triacetin) is used in Food, Beverage, Pharmaceutical, Health & Personal care products.
Glycerol triacetate (triacetin) is used as an emulsifier, an agent that forms or preserves a mixture of substances that are normally immiscible, such as oil and water.


Glycerol triacetate (triacetin) is also used as a humectant, a substance that helps prevent food from drying out.
In beverage, Glycerol triacetate (triacetin) is used as emulsifier and flavor enhancer.
Glycerol triacetate (triacetin) is one of the few food grade carrier for flavors and fragrances.


Glycerol triacetate (triacetin) is used in food and cosmetic products.
It’s high solvency power and high volatility make Glycerol triacetate (triacetin) a good solvent and fixative for flavors and fragrances.
Glycerol triacetate (triacetin) is a triester of glycerol manufactured through chemical synthesis, available as Clear transparent oily liquid.


Glycerol triacetate (triacetin) is widely used as emulsifier.
Cosmetics and fragrances: Glycerol triacetate (triacetin) is used Humectant, plasticiser, solvent and fixative for fragrances, also used in dye synthesis and perfume fixative.


Antimicrobial agent: Glycerol triacetate (triacetin) is able to suppress or inhibit the growth and replication of a broad spectrum of microorganisms such as bacteria, fungi and viruses by making the stratum corneum temporarily bactericidal and fungicidal.
Film-forming agent: Glycerol triacetate (triacetin) produces, upon application, a very thin continuous film with an optimal balance of cohesion, adhesion and stickiness on skin, hair or nails to counteract or limit damage from external phenomena such as chemicals, UV rays and pollution.


Notably, Glycerol triacetate (triacetin) displays amphiphilic properties, enabling it to interact with both polar and non-polar molecules. his unique characteristic allows for the dissolution and stabilization of a wide range of compounds.
Moreover, Glycerol triacetate (triacetin) has been found to have diverse biochemical and physiological effects.


Glycerol triacetate (triacetin) has demonstrated the ability to inhibit specific enzymes such as cyclooxygenase and lipoxygenase.
Additionally, Glycerol triacetate (triacetin) has shown a reduction in the expression of certain genes involved in inflammation and cancer.
Moreover, Glycerol triacetate (triacetin) has exhibited a variety of biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties.


Glycerol triacetate (triacetin) is often used as a food additive because of its wetting, solvent and plasticizer properties.
In pharmaceuticals, Glycerol triacetate (triacetin) is used as a plasticizer in the production of gelatin capsules.
In cosmetics, Glycerol triacetate (triacetin) is used for its moisturizing and emollient properties.


Glycerol triacetate (triacetin)-mediated acetate supplementation may provide a new safe chemotherapeutic adjuvant to reduce the growth of glioma tumours, particularly the more rapidly proliferating glycolytic and hypoacetylated mesenchymal glioma tumours.
Glycerol triacetate (triacetin) is used as a substrate for lipase determination.


Labelled as a humectant with the number E1518 in the European food additives list.
Glycerol triacetate (triacetin) is used in cooking food and dairy products to promote fermentation.
Glycerol triacetate (triacetin) is used Chromatographic fixative, solvent, hardener, curing agent that can absorb carbon dioxide from natural gas.


Furthermore, Glycerol triacetate (triacetin) has demonstrated the ability to hinder the growth of specific cancer cells and mitigate the toxicity of certain drugs.
Thus, in the realm of scientific research, Glycerol triacetate (triacetin) finds extensive applications in vitro studies.


In summary, Glycerol triacetate (triacetin) is a versatile triester utilized as a plasticizer, solvent, and stabilizer.
With its amphiphilic nature, Glycerol triacetate (triacetin) can interact with a wide range of molecules, dissolve various compounds, and stabilize solutions.


Glycerol triacetate (triacetin) has shown significant biochemical and physiological effects, such as enzyme inhibition and gene expression modulation.
Furthermore, Glycerol triacetate (triacetin)'s applications extend to diverse areas of scientific research, offering valuable contributions to in vitro studies.


Glycerol triacetate (triacetin) is used Environmentally friendly plasticiser containing no phthalates.
Glycerol triacetate (triacetin) can be used as a plasticiser and solvent of printing ink, nitrocellulose, cellulose acetate, ethacellulose and ellulose acetate butyrate.
In casting, Glycerol triacetate (triacetin) is used as a moulding sand hardener.


Application generally takes place in a spray chamber where Glycerol triacetate (triacetin) is applied to the filter in the form of an aqueous aerosol.
Glycerol triacetate (triacetin) is used in the food industry as a solvent for flavouings, and is used as a humectant in pharmaceutical products.
Glycerol triacetate (triacetin) is also used as a plasticiser and a solvent.


Glycerol triacetate (triacetin) is approved to use as food additive in EU.
Glycerol triacetate (triacetin) is used Plasticizer for paints and adhesives, additive for special hardeners, adhesive for cigarette filter production, plasticizer for chewing gum or as a flavor carrier, food additive E 1518.


Glycerol triacetate (triacetin) is also a component of casting liquor with TG and as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent.
Glycerol triacetate (triacetin) can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.


Glycerol triacetate (triacetin) is used food ingredients, HTF - food/feed/beverage processing, Other-food chemicals, and Packaging inks non-food contact.
Glycerol triacetate (triacetin) is used as an ingredient in many food and cosmetic products.
Glycerol triacetate (triacetin)'s high solvency power and low volatility make triacetin a good solvent and fixative for many flavors and fragrances.


Glycerol is a very well-known substance which counts a great variety of applications: HUMECTANT, solvent, and SWEETENER in foodstuff, additive or solvent in the manufacture of perfumes, inks or automobile antifreeze, humectant in tobacco industry, plasticizer and lubricants for the plastic industry, smoothing agent, emollient, lubricant and humectant in personal care preparations and pharmaceutical products where in some cases has the function of ACTIVE PRINCIPLE INGREDIENT, such as in GLYCEROL SUPPOSITORIES.


One of Glycerol triacetate (triacetin)'s main uses is as a plasticizer in chewing gum.
Glycerol triacetate (triacetin) is often used as a food additive, for instance as a solvent in flavourings, and for its humectant function.
Glycerol triacetate (triacetin) is mainly used in dairy products, cheese, processed fruit, dried vegetables, confectionery, etc.


Glycerol triacetate (triacetin) has been considered as a possible source of food energy in artificial food regeneration systems on long space missions.
It is believed to be safe to get over half of one's dietary energy from Glycerol triacetate (triacetin).
Glycerol triacetate (triacetin) also has some anti-fungal activity.


Glycerol triacetate (triacetin) is used as a plasticizer and fragrance fixative, ink solvent, also used in medicine and dye synthesis.
Glycerol triacetate (triacetin) is used as a chromatographic fixative, solvent, toughener and fragrance fixative.
Humectants; carrier solvents; plasticizers; Glycerol triacetate (triacetin) can absorb carbon dioxide from the natural gas.


Glycerol triacetate (triacetin) is used in the production of cosmetics, pharmaceuticals and dyes, plasticizers for cigarette filter rods, and so on.
Glycerol triacetate (triacetin) is used applied in cosmetics, casting, medicine, dyes and other industries.
Glycerol triacetate (triacetin) is non-toxic, non-irritating.


Glycerol triacetate (triacetin) is used as the substrate for the determination of lipase, perfume fixative, solvent, gas chromatographic fixative (maximum temperature of 85 ℃, solvent: methanol, chloroform), separation of gas and aldehyde analysis.
Glycerol triacetate (triacetin) is an organic compound which is widely used in food, flavors & fragrances, pharmaceutical, cigarette, plasticiser, foundry, and textiles.


Glycerol triacetate (triacetin) has been shown to have a high resistance to solid phase microextraction and can be used as a model system for studying the interactions of triacetates with other materials.
Glycerol triacetate (triacetin) is pharmaceutical excipient used in manufacturing of capsules and tablets, and has been used as a humectant, plasticizer, and solvent.


The reaction solution containing Glycerol triacetate (triacetin) is acidic, which may lead to problems with water permeability if not properly treated.
This analytical method utilizes hydrogen bonding interactions between glycerol and glycerine molecules to measure the concentration of each component in the sample.
Glycerol triacetate (triacetin) is also used in the perfume and cosmetic industries.


-Pharmaceutical Applications:
Glycerol triacetate (triacetin) is mainly used as a hydrophilic plasticizer in both aqueous and solvent-based polymeric coating of capsules, tablets, beads, and granules; typical concentrations used are 10–35% w/w.
Glycerol triacetate (triacetin) is used in cosmetics, perfumery, and foods as a solvent and as a fixative in the formulation of perfumes and flavors.


-In Health and Personal care
Glycerol triacetate (triacetin), an oil, is the triester of Glycerol and Acetic Acid.
In cosmetics and personal-care products, Glycerol triacetate (triacetin) is used in makeup as well as in nail polish and nail enamel removers.
Glycerol triacetate (triacetin) helps cleanse the skin or prevent odor by destroying or inhibiting the growth of microorganisms.
Glycerol triacetate (triacetin) is also a plasticizer and commonly used carrier for flavors and fragrances.


-Fragrance:
Glycerol triacetate (triacetin) plays a decisive and important role in the formulation of cosmetic products as it provides the possibility of enhancing, masking or adding fragrance to the final product, increasing its marketability.
Glycerol triacetate (triacetin) is able to create a perceptible pleasant odour, masking a bad smell.
The consumer always expects to find a pleasant or distinctive scent in a cosmetic product.


-Clinical Use of Glycerol triacetate (triacetin):
Glycerol triacetate (triacetin) is a colorless, oilyliquid with a slight odor and a bitter taste.
Glycerol triacetate (triacetin) issoluble in water and miscible with alcohol and most organicsolvents.
The activity of Glycerol triacetate (triacetin) is a result of the acetic acid releasedby hydrolysis of the compound by esterases presentin the skin.
Acid release is a self-limiting process because the esterases are inhibited below pH 4.


-Plasticiser uses of Glycerol triacetate (triacetin).
Glycerol triacetate (triacetin) is added to the formulation with the purpose of retaining fragrance and colour, increasing flexibility, flowability, deformability, durability of various ingredients allowing better processing.
Glycerol triacetate (triacetin) softens and makes flexible synthetic polymers that otherwise could not be easily processed, stretched or deformed.


-Solvent uses of Glycerol triacetate (triacetin):
Glycerol triacetate (triacetin) is the substance for dissolving or dispersing surfactants, oils, dyes, flavourings, bactericidal preservatives in solution.
In fact, Glycerol triacetate (triacetin) dissolves other components present in a cosmetic formulation.
Solvents are generally liquid (aqueous and non-aqueous).


-Medical uses of Glycerol triacetate (triacetin):
Glycerol triacetate (triacetin) is both the shortest chain triglyceride (SCT), which contains fatty acids with two carbon atoms, and the only triglyceride that is up to 6 per cent soluble in water.
Glycerol triacetate (triacetin)'s approval by the Food and Drug Administration as a safe human food ingredient has led to a series of studies examining its potential as a therapeutic agent.



FOOD USES OF GLYCEROL TRIACETATE (TRIACETIN):
As a food additive, the influence of the choice of aromatic solvent between propylene glycol (PG) or Glycerol triacetate (triacetin) (TA) was investigated during the accelerated shelf life test (ASL) of biscuits and tartlets.
In particular, the differential effect on the stability of added vanillin, the natural baked marker compound 5- (hydroxymethyl) furfural (HMF), specific oxidative rancidity markers (2,4-decadienal, 2,4-heptadienal) and the structural parameters of hardness and fractureability.

More HMF was formed during baking of biscuits prepared with Glycerol triacetate (triacetin); these biscuits were also more stable to oxidative degradation and vanillin loss during ageing than biscuits prepared with PG.
Fresh Glycerol triacetate (triacetin) biscuits were significantly more brittle than fresh PG biscuits.

There was no impact of the choice of solvent on hardness.
Sensory evaluation of hardness, vanilla flavour and oily note were tested during the ASL-tests.
There was no significant impact on the retention of sensory ratings for PG or Glycerol triacetate (triacetin) biscuits.



FUCTION AND CHARACTERISTICS OF GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) is used as a solvent for flavours; it also has some anti-fungal activity.


DIETARY RESTRICTIONS OF GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) can be used by all religious groups, vegetarians and vegans.



FUNCTIONS OF GLYCEROL TRIACETATE (TRIACETIN):
1. Flavor / Flavoring / Flavor Enhancer - Provides or enhances a particular taste or smell.
2. Fragrance / Fragrance Component - Provides or enhances a particular smell or odor.
3. Humectant - Binds with water to increase skin hydration. Also enhances water absorption of the skin



CHEMICAL PROPERTIES OF GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) has a very faint, fruity odor. It has a mild, sweet taste that is bitter above 0.05%.
Glycerol triacetate (triacetin) is a colorless liquid; slight fatty odor; bitter taste.
Glycerol triacetate (triacetin) is slightly soluble in water; very soluble in alcohol, ether, and other organic solvents.

Glycerol triacetate (triacetin) is a colorless, viscous liquid with a slightly fatty odor.
Glycerol triacetate (triacetin) is a colorless, odorless oily liquid. It is miscible with ethanol, ether, benzene, chloroform and other organic solvents, soluble in acetone, insoluble in mineral oil.
Glycerol triacetate (triacetin) is slightly soluble in water. 25 ° C in water solubility of 5.9g / 100ml.



FUNCTIONS OF GLYCEROL TRIACETATE (TRIACETIN):
*Fatty Acids & Lipids
*Flavoring Agent
*Solubilizer
*Solvent
*Carrier
*Antiseptic



WHAT IS GLYCEROL TRIACETATE (TRIACETIN) AND HOW DOES GLYCEROL TRIACETATE (TRIACETIN) WORK?
Glycerol triacetate (triacetin) (glycerine triacetate and 1,2,3-propanetriyl triacetate) is an ester compound of glycerin and acetic acid.
Glycerol triacetate (triacetin) is a colorless liquid that smells oily to rancid.
Glycerol triacetate (triacetin)´s used as an emollient, as a humectant or as a flavor carrier in various industries.
Glycerol triacetate (triacetin) has a viscosity (7.83 cSt at 40 oC) .



FUNCTIONAL CLASS OF GLYCEROL TRIACETATE (TRIACETIN):
*Flavouring Agent
*FLAVOURING_AGENT
*Food Additives
*CARRIER_SOLVENT
*HUMECTANT



MORE ADDITIVES AND FOOD ADDITIVES OF GLYCEROL TRIACETATE (TRIACETIN):
*Shellac wax
*Conditioning agents
*Solvents
*Fumaric acid
*Flame retardants
*Maleic anhydride functionalized polymers



PRODUCTION METHODS OF GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) is prepared by the esterification of glycerin with acetic anhydride.


PREPARATION OF GLYCEROL TRIACETATE (TRIACETIN):
By direct reaction of glycerol with acetic acid in the presence of Twitchell’s reagent, or in benzene solution of glycerol and boiling acetic acid in the presence of a cationic resin (Zeo-Karb H) pretreated with dilute H2SO4.



MANUFACTURING PROCESS OF GLYCEROL TRIACETATE (TRIACETIN):
200 grams of allyl acetate, 450 grams of glacial acetic acid and 3.71 grams of cobaltous bromide were charged to the reactor and the mixture was heated to 100°C.
Pure oxygen was then introduced into the reactor below the surface of the liquid reaction mixture at the rate of 0.5 standard cubic feet per hour.

Initially, all of the oxygen was consumed, but after a period of time oxygen introduced into the mixture passed through unchanged.
During the course of the reaction, a small quantity of gaseous hydrogen bromide (a total of 1.9 grams) was introduced into the reaction zone, along with the oxygen.

The reaction was allowed to continue for 6 hours following which the reaction mixture was distilled.
Essentially complete conversion of the allyl acetate took place.
A yield of 116 grams of Glycerol triacetate (triacetin) was obtained, this being accomplished by distilling the Glycerol triacetate (triacetin) overhead from the reaction mixture, at an absolute pressure of approximately 13 mm of mercury.



PRODUCTION OF GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) can be derived from the esterification of glycerol and acetic acid.
After preheating glycerol to 50-60 ° C, add acetic acid, benzene and sulfuric acid.
Heat and stir for refluxing dehydration, and recycle the benzene.
Then add acetic anhydride for heating of 4h.

After cooling, the mixture was neutralized with 5% sodium carbonate to pH 7, and the crude layer was dried and the crude oil was dried with calcium chloride.
Distill under reduced pressure, collect the 128-131 ° C (0.93 kPa) fraction, namely Glycerol triacetate (triacetin).



FOOD ADDITIVES OF GLYCEROL TRIACETATE (TRIACETIN):
*Polyglycerol polyricinoleate
*Citrate
*Potassium metabisulphite / Potassium disulphite
*Sugar substitutes
*Flavorants / fragrances
*E vitamins



PRODUCTION OF GLYCEROL TRIACETATE (TRIACETIN):
For commercial use, Glycerol triacetate (triacetin) is produced synthetically from acetic acid and glycerol.



SYNTHESIS OF GLYCEROL TRIACETATE (TRIACETIN):
Glycerol triacetate (triacetin) was first prepared in 1854 by the French chemist Marcellin Berthelot.
Glycerol triacetate (triacetin) was prepared in the 19th century from glycerol and acetic acid.
Glycerol triacetate (triacetin)'s synthesis from acetic anhydride and glycerol is simple and inexpensive.
3 (CH3CO)2O + 1 C3H5(OH)3 → 1 C3H5(OCOCH3)3 + 3 CH3CO2H

This synthesis has been conducted with catalytic sodium hydroxide and microwave irradiation to give a 99% yield of Glycerol triacetate (triacetin).
Glycerol triacetate (triacetin) has also been conducted with a cobalt(II) Salen complex catalyst supported by silicon dioxide and heated to 50 °C for 55 minutes to give a 99% yield of Glycerol triacetate (triacetin).



SAFETY OF GLYCEROL TRIACETATE (TRIACETIN):
The US Food and Drug Administration has approved it as Generally Recognized as Safe food additive and included it in the database according to the opinion from the Select Committee On GRAS Substances (SCOGS).
Glycerol triacetate (triacetin) is included in the SCOGS database since 1975.



CONTENT ANALYSIS OF GLYCEROL TRIACETATE (TRIACETIN):
Accurately weigh about 1g of the sample, put it into a suitable pressure bottle, add 25 mL of 1mol / L. potassium hydroxide solution and 15 mL of isopropyl alcohol, add stopper, wrap with cloth and put it in a canvas bag.
Put it into the water bath of 98 ℃ ± 2 ℃ for 1h, and the water level in the water bath should be slightly higher than the bottle level.

Take the bottle out from the bag, cool it to room temperature in the air, unfold the cloth and stopper to release the residual pressure in the bottle, and then remove the cloth.
Add 6 to 8 drops of phenolphthalein test solution (TS-167), apply 0.5mol / L sulfuric acid for titration of excess alkali until the pink could just disappeared.

At the same time, perform a blank test.
Each mL of 0.5mol / L sulfuric acid is equivalent to 36.37 mg of Glycerol triacetate (triacetin) (C9H14O6).



THE NAME DEFINES THE STRUCTURE OF GLYCEROL TRIACETATE (TRIACETIN) MOLECULE:
Glycerol triacetate (triacetin) refers to a triester that is derived from glycerol and acetic acid.
The prefix "tri-" indicates that there are three acetic acid molecules esterified to each glycerol molecule.
The synthesis process of Glycerol triacetate (triacetin) takes place in several stages:

*Preparation of glycerin:
The process begins with the preparation of glycerin, which is commercially available.

*Esterification:
Glycerol reacts with acetic acid in the presence of an acid catalyst, often sulfuric acid.
The reaction is heated, which initiates the esterification process.
This reaction causes the formation of Glycerol triacetate (triacetin) and water.

*Separation:
The reaction mixture is allowed to cool.
Glycerol triacetate (triacetin), being less polar than water, will separate from the reaction mixture.

*Purification:
Glycerol triacetate (triacetin) is then purified.
This typically involves distillation, where Glycerol triacetate (triacetin) is heated and vapors are collected and condensed.
This process helps to remove any remaining impurities.

*Quality control:
The final product is tested to ensure it meets the specifications required for use in the intended applications.
This includes checking its purity, color and smell.

It is in the form of an odourless and colourless clear liquid, starts to sublimate when heated to 160°C and at 300°C, decomposes to chlorine and phosphorus trichloride.
Soluble in water, soluble in carbon disulphide, carbon tetrachloride and benzoyl chloride.
In moist air it is hydrolysed into phosphoric acid and hydrochloric acid.



PHYSICAL and CHEMICAL PROPERTIES of GLYCEROL TRIACETATE (TRIACETIN):
Appearance: Clear, colorless, odorless liquid
Triacetin content: ≥99.5%
Acidity (As HAC): ≤0.01%
Moisture: ≤0.05%
Color, Pt-Co: ≤15
Refractive Index (20℃): 1.430-1.433
Specific Gravity (20℃): 1.157-1.162
As: ≤0.0001
Pb: ≤0.0005
Residue on Ignition: ≤0.05
CAS: 102-76-1
Molecular Formula :C9H14O6
Molecular Weight: 218.20
Storage Details: Ambient
Harmonised Tariff Code: 29153900
Refractive Index: 1.4300 - 1.4332 @ 20 Deg C
Specific Gravity: 1.150 - 1.166 @ 20 Deg C
Purity: >95%
Appearance: Colourless liquid

Formula: C₉H₁₄O₆
MW: 218,21 g/mol
Boiling Pt: 258 °C (1013 hPa)
Melting Pt: –78 °C
Density: 1,1596 g/cm³ (20 °C)
Flash Pt: 138 °C (closed cup)
Storage Temperature: Ambient
MDL Number: MFCD00008716
CAS Number: 102-76-1
EINECS: 203-051-9
Merck Index: 12,09721
Melting point: 3 °C(lit.)
Boiling point: 258-260 °C(lit.)
Densit: 1.16 g/mL at 25 °C(lit.)
vapor density: 7.52 (vs air)
vapor pressure: 0.00248 mm Hg @ 250C
FEMA: 2007 | (TRI-)ACETIN
refractive index: n25/D 1.429-1.431(lit.)
Flash point: 300 °F
storage temp.: Sealed in dry,Room Temperature

solubility: Soluble in water, miscible with ethanol (96 per cent) and toluene.
form: Liquid
color: Clear colorless
Odor: Characteristic odour
Odor Type: fruity
explosive limit 1.05%, 189°F
Water Solubility: 64.0 g/L (20 ºC)
Merck: 14,9589
JECFA Number: 920
BRN: 1792353
Stability: Stable.
Incompatible with strong oxidizing agents.
InChIKey: URAYPUMNDPQOKB-UHFFFAOYSA-N
LogP: 0.25
FDA 21 CFR: 184.1901; 582.1901; 175.300; 175.320; 310.545
Substances Added to Food (formerly EAFUS): TRIACETIN (GLYCEROL TRIACETATE)
CAS DataBase Reference: 102-76-1(CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: XHX3C3X673
NIST Chemistry Reference: 1,2,3-Propanetriol, triacetate(102-76-1)

EPA Substance Registry System: Glyceryl triacetate (102-76-1)
Molecular Weight： 218.20400
Exact Mass： 218.20
EC Number： 203-051-9
UNII： XHX3C3X673
ICSC Number： 1203
NSC Number： 757364|4796
DSSTox ID： DTXSID3026691
Color/Form： Colorless liquid|Colorless somewhat oily liquid
HScode： 2915390090
PSA： 78.90000
XLogP3： 0.2
Appearance： Liquid
Density： 1.1562 g/cm3 @ Temp: 25 °C
Melting Point： -78 °C
Boiling Point： 258-260 °C

Flash Point： 148ºC
Refractive Index： 1.429-1.433
Water Solubility： H2O: 64.0 g/L (20 ºC)
Storage Conditions： Keep container tightly closed in a dry and well-ventilated place.
Vapor Pressure： 0.0141mmHg at 25°C
Vapor Density： 7.52 (vs air)
Flammability characteristics： Lower flammable limit: 1.0% by volume at 373 deg F (189 deg C)
Explosive limit： 1.05%, 189°F
Odor： Slightly fatty odor
Taste： MILD, SWEET TASTE, BITTER ABOVE 0.05%
Henrys Law Constant： Henry's Law constant = 1.2X10-8 at 25 °C atm-cu m/mole at 25 °C (est)
Experimental Properties： Hydroxyl radical reaction rate constant = 8.5X10-12 cu cm/mole-sec at 25 °C (est)
Autoignition Temperature： 812 °F (433 °C)|433 °C
Flammable Limits： Lower flammable limit: 1.0% by volume at 373 °F (189 °C)



FIRST AID MEASURES of GLYCEROL TRIACETATE (TRIACETIN):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of GLYCEROL TRIACETATE (TRIACETIN):
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of GLYCEROL TRIACETATE (TRIACETIN):
-Extinguishing media:
--Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
--Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of GLYCEROL TRIACETATE (TRIACETIN):
-Control parameters:
Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Use impervious clothing.
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of GLYCEROL TRIACETATE (TRIACETIN):
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.



STABILITY and REACTIVITY of GLYCEROL TRIACETATE (TRIACETIN):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
1,2,3-Propanetriol, triacetate
Acetin, tri-
Enzactin
Fungacetin
Glycerin triacetate
Glycerol triacetate
Glyceryl triacetate
Glyped
Kesscoflex TRA
Triacetine
Vanay
Kodaflex triacetin
Triacetyl glycerine
Triacetyl glycerin
Triacetyl glycerol
1,2,3-Propanetriol, 1,2,3-triacetate
NSC 4796
Glycerol, acetylated
2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate
GLYCEROL TRIACETATE
Triacetine
GLYCERYL TRIACETATE
triacetate
GLYCERIN TRIACETATE
Vanay
Enzactin
Fungacetin
1,2,3-TRIACETOXYPROPANE
2,3-diacetyloxypropyl acetate
1,2,3-Propanetriol Triacetate
1,2,3-Propanetriyl Triacetate
1,2,3-Triacetoxypropane
1,2,3-Triacetylglycerol
2-(Acetyloxy)-1-[(Acetyloxy)Methyl]Ethyl Acetate
Glycerin Triacetate
Glycerol Triacetate
Glyceryl Triacetate
1,2,3-Propanetriol,1,2,3-triacetate
Acetin,tri-
1,2,3-Propanetriol,triacetate
Enzactin
Fungacetin
Glycerol triacetate
Glyceryl triacetate
Kesscoflex TRA
Triacetin
Triacetine
Triacetylglycerin
Vanay
Glycerin triacetate
Glyped
1,2,3-Triacetoxypropane
Estol 1581
Ujostabil
Triacetylglycerol
Priacetin 1580
Priacetin 1581
NSC 4796
Edenor GTA
DRA 150
Speziol GTA
Kollisolv GTA
Triacetin 1584
Triacetain glycerol
Captex 500
Alphacure 920
DAR 150
Edenor GTA Kosher
106C
GTA
2,3-Diacetyloxypropyl acetate
1,3-Bis(acetyloxy)propan-2-yl acetate
DRA-150
2102168-03-4

Glycerol tripalmitate is a solid, waxy substance at room temperature.
It is derived from the esterification of glycerol and palmitic acid.
Glycerol tripalmitate has a white or off-white color.
Glycerol tripalmitate is odorless.

CAS number: 555-44-2
EC number: 209-008-0



APPLICATIONS


Glycerol tripalmitate (tripalmitin) finds various applications in different industries.
Here are some of its key applications:

Food Industry:
Glycerol tripalmitate is used as a food additive, functioning as a thickening agent, emulsifier, and stabilizer.
Glycerol tripalmitate improves the texture and stability of food products like margarine, spreads, confectionery items, and baked goods.

Cosmetics and Personal Care:
Glycerol tripalmitate is utilized in skincare and cosmetic formulations as an emollient and moisturizing agent.
Glycerol tripalmitate helps to enhance the smoothness and softness of skin, making it an ingredient in creams, lotions, lip balms, and moisturizers.

Pharmaceuticals:
In the pharmaceutical industry, glycerol tripalmitate acts as a binder in tablet manufacturing.
Glycerol tripalmitate helps to hold the active ingredients together and ensure the integrity and stability of solid dosage forms.

Industrial Lubricants:
Due to its lubricating properties, glycerol tripalmitate is used as a lubricant in various industrial applications.
Glycerol tripalmitate can reduce friction and provide lubrication in machinery and equipment, particularly under high-temperature conditions.

Biofuel Production:
Glycerol tripalmitate can be used as a feedstock for biodiesel production.
Through transesterification, it can be converted into fatty acid methyl esters (FAME), which are commonly used as biofuels.

Research and Laboratory Use:
Glycerol tripalmitate is used in scientific research and laboratory settings as a reference compound or as a substrate for various enzymatic studies and lipid metabolism research.

Release Agent:
Glycerol tripalmitate can act as a release agent in various industries, including food processing and mold release applications.
Glycerol tripalmitate helps prevent sticking and adhesion of materials to surfaces, molds, or equipment during production processes.

Candle Manufacturing:
Due to its waxy nature and solid form, glycerol tripalmitate can be utilized in candle manufacturing.
Glycerol tripalmitate can serve as a component in candle formulations, contributing to the texture, hardness, and burn characteristics of the candles.

Carbon Paper Production:
Glycerol tripalmitate has been employed in the production of carbon paper, a type of paper used for creating duplicate copies of written or printed documents.
Glycerol tripalmitate acts as a coating on the paper surface, allowing the transfer of ink or graphite impressions to subsequent sheets.

Calibration Standards:
In analytical laboratories, glycerol tripalmitate can be used as a calibration standard for certain analytical techniques and instruments.
Glycerol tripalmitate serves as a reference compound for the identification and quantification of specific analytes or for verifying instrument performance.

Biomedical Research:
Glycerol tripalmitate has been studied for its potential applications in drug delivery systems and as a carrier for bioactive compounds.
Research is being conducted to explore its use in controlled-release formulations and nanostructured lipid carriers.

Energy Storage:
Triglycerides, including glycerol tripalmitate, have gained attention as a potential renewable energy storage medium.
They have been investigated as a source of stored energy, where the fatty acids can be converted back into usable energy through processes like biodiesel production or direct combustion.


Glycerol tripalmitate is used as a thickening agent, emulsifier, and stabilizer in the food industry.
Glycerol tripalmitate improves the texture and stability of food products like margarine, spreads, and baked goods.

In cosmetics and personal care products, glycerol tripalmitate acts as an emollient, enhancing the smoothness and softness of the skin.
Glycerol tripalmitate is commonly found in creams, lotions, lip balms, and moisturizers.
Glycerol tripalmitate serves as a binder in the pharmaceutical industry, ensuring the integrity and stability of tablets.
Glycerol tripalmitate is utilized in the production of solid dosage forms, such as tablets and capsules.

Glycerol tripalmitate acts as a release agent, preventing sticking and adhesion in food processing and mold release applications.
Glycerol tripalmitate finds use in candle manufacturing, contributing to the texture and burn characteristics of candles.
Glycerol tripalmitate can be employed in the production of carbon paper, facilitating the transfer of impressions to subsequent sheets.

In analytical laboratories, glycerol tripalmitate can be used as a calibration standard for certain analytical techniques and instruments.
Glycerol tripalmitate serves as a reference compound for identification and quantification purposes.
Glycerol tripalmitate has potential applications in drug delivery systems and as a carrier for bioactive compounds in biomedical research.

Glycerol tripalmitate has been studied for its use in controlled-release formulations and nanostructured lipid carriers.
Glycerol tripalmitate can act as a lubricant in various industrial applications, reducing friction and providing lubrication in machinery and equipment.
Glycerol tripalmitate is a potential feedstock for biodiesel production, contributing to renewable energy sources.
Glycerol tripalmitate is being explored for its use in energy storage, where the fatty acids can be converted back into usable energy.

Glycerol tripalmitate is used in the calibration of instruments and analytical techniques in scientific research.
Glycerol tripalmitate finds application in the production of specialty papers, including carbonless copy paper.

Glycerol tripalmitate is utilized in the formulation of coatings and paints, enhancing their texture and performance.
Glycerol tripalmitate is a component in the production of industrial adhesives and sealants.
Glycerol tripalmitate is used in the development of specialty chemicals, such as surfactants and lubricants.
Glycerol tripalmitate can be utilized as a carrier or encapsulating agent in the encapsulation of flavors, fragrances, or active ingredients.

Glycerol tripalmitate is employed in the production of lipsticks and other cosmetic products with desirable consistency and texture.
Glycerol tripalmitate is used in the manufacturing of soap, contributing to its texture and moisturizing properties.
Glycerol tripalmitate finds application in research and development, serving as a reference compound and substrate for lipid metabolism studies.



DESCRIPTION


Glycerol tripalmitate, also known as tripalmitin, is a chemical compound classified as a triglyceride.
Glycerol tripalmitate is composed of three fatty acid chains, specifically palmitic acid, esterified to a glycerol molecule.
Each of the three hydroxyl groups of glycerol is esterified with one palmitic acid molecule.

The chemical formula of glycerol tripalmitate is C₅₃H₁₀₀O₆, indicating its composition of 53 carbon atoms, 100 hydrogen atoms, and 6 oxygen atoms.
Glycerol tripalmitate is an example of a saturated fat due to the presence of palmitic acid, a saturated fatty acid.

Glycerol tripalmitate is a solid at room temperature and is insoluble in water.
Glycerol tripalmitate is commonly found in various natural sources, including animal fats and vegetable oils.
Glycerol tripalmitate serves as a form of energy storage in organisms and can be hydrolyzed by enzymes called lipases to release glycerol and three molecules of palmitic acid.

In industrial applications, glycerol tripalmitate is used as a thickening agent, emulsifier, and stabilizer in food products, cosmetics, and pharmaceuticals.
Its properties and functionality make it useful in enhancing texture, viscosity, and stability of formulations.

Glycerol tripalmitate is a solid, waxy substance at room temperature.
It is derived from the esterification of glycerol and palmitic acid.
Glycerol tripalmitate has a white or off-white color.
Glycerol tripalmitate is odorless.

Glycerol tripalmitate is insoluble in water.
Glycerol tripalmitate has a high melting point, typically around 63-65 degrees Celsius.

Glycerol tripalmitate is classified as a triglyceride due to its composition of three fatty acid chains.
Glycerol tripalmitate is primarily found in natural sources such as animal fats and vegetable oils.
Glycerol tripalmitate is considered a saturated fat due to the presence of palmitic acid.

Glycerol tripalmitate is a major component of many solid fats and oils.
Glycerol tripalmitate serves as an energy storage molecule in organisms.
Glycerol tripalmitate can be hydrolyzed by enzymes called lipases to release glycerol and three palmitic acid molecules.

Glycerol tripalmitate is used as an emollient in skincare and cosmetic products.
Glycerol tripalmitate helps to improve the texture and moisturizing properties of creams and lotions.
Glycerol tripalmitate is also utilized as a thickening agent in food products.

Glycerol tripalmitate can enhance the mouthfeel and stability of various food formulations.
Glycerol tripalmitate acts as a binder in the production of tablets in the pharmaceutical industry.

Glycerol tripalmitate helps to hold the active ingredients together in solid dosage forms.
Glycerol tripalmitate is non-toxic and considered safe for consumption and topical use.
Glycerol tripalmitate has a long shelf life and is resistant to oxidation.
Glycerol tripalmitate is often used as a lubricant in industrial applications.

Glycerol tripalmitate has low volatility, making it suitable for use in high-temperature processes.
Glycerol tripalmitate is biodegradable and environmentally friendly.
Glycerol tripalmitate has a wide range of applications, including in food, cosmetics, pharmaceuticals, and personal care products.
Glycerol tripalmitate is subject to quality control measures to ensure its purity and safety in various applications.



PROPERTIES


Physical Properties:

Physical State: Solid
Appearance: White or off-white color
Odor: Odorless
Melting Point: Approximately 63-65 degrees Celsius
Solubility: Insoluble in water
Solubility in Other Solvents: Soluble in organic solvents like ethanol, chloroform, and ether
Density: Varies depending on temperature and crystalline form


Chemical Properties:

Chemical Formula: C₅₃H₁₀₀O₆
Molecular Weight: Approximately 809.43 g/mol
Chemical Family: Triglyceride (ester of glycerol and palmitic acid)
Lipid Class: Neutral lipid
Fatty Acid Composition: Comprised of three palmitic acid molecules (C₁₆H₃₁COOH) esterified to a glycerol molecule
Saponification Value: The amount of alkali required to hydrolyze the compound to yield glycerol and fatty acids


Thermal and Stability Properties:

High Melting Point: Gives it a solid form at room temperature
Stability: Relatively stable under normal conditions, resistant to oxidation
Decomposition: Subject to thermal decomposition at elevated temperatures


Functional Properties:

Thickening Agent: Enhances viscosity and texture in food and cosmetic formulations
Emulsifier: Helps stabilize emulsions by promoting the dispersion of oil and water phases
Stabilizer: Improves the stability and shelf life of food and cosmetic products
Lubricating Properties: Exhibits lubricating characteristics, reducing friction in industrial applications
Moisturizing Agent: Provides hydration and moisturization in skincare and cosmetic products
Binding Agent: Holds together active ingredients in pharmaceutical tablet formulations



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air.
If breathing is difficult, provide oxygen if available and seek medical attention.


Skin Contact:

Remove contaminated clothing and wipe off excess glycerol tripalmitate from the skin.
Wash the affected area thoroughly with mild soap and water.
If irritation or redness develops, seek medical advice.
In case of extensive skin contact or if irritation persists, seek medical attention.


Eye Contact:

Rinse the eyes gently with lukewarm water for at least 15 minutes, keeping the eyelids open.
Remove contact lenses, if applicable, after the initial rinsing.
Seek immediate medical attention and bring the Safety Data Sheet or product container for reference.


Ingestion:

Rinse the mouth with water, but do not swallow any liquid.
Do not induce vomiting unless instructed to do so by medical professionals.
Seek immediate medical attention and bring the Safety Data Sheet or product container for reference.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear suitable protective clothing, including gloves and safety goggles, to prevent direct contact with the substance.
Ensure adequate ventilation in the working area to minimize inhalation of vapors or dust particles.

Avoid Ingestion and Inhalation:
Do not eat, drink, or smoke while handling glycerol tripalmitate.
Avoid inhalation of dust or vapors. Use appropriate respiratory protection if needed.

Avoid Skin and Eye Contact:
Prevent direct skin contact by wearing appropriate protective clothing, including gloves and long-sleeved clothing.
In case of accidental contact, promptly wash the affected area with soap and water.
Use safety goggles or a face shield to protect the eyes from potential splashes or contact.

Spill and Leak Response:
In the event of a spill or leak, contain the material and prevent it from spreading.
Absorb or collect spilled substance using suitable absorbent materials.
Dispose of the collected material in accordance with applicable regulations.


Storage:

Storage Temperature:
Store glycerol tripalmitate in a cool, dry, well-ventilated area.
Keep the substance away from direct sunlight and sources of heat or ignition.

Avoid Incompatible Materials:
Store glycerol tripalmitate away from strong oxidizing agents and incompatible materials.
Ensure proper segregation and storage to prevent chemical reactions or hazards.

Packaging:
Store the substance in tightly sealed, properly labeled containers or drums.
Use appropriate packaging materials to avoid leakage or damage during storage or transportation.

Fire Precautions:
Keep the substance away from open flames, sparks, or hot surfaces.
Implement suitable fire protection measures in the storage area, such as fire-resistant construction and extinguishing systems.

Specific Storage Recommendations:
Follow any specific storage recommendations provided by the manufacturer or stated in the Safety Data Sheet.
Comply with local regulations and guidelines for the safe storage of glycerol tripalmitate.



SYNONYMS


Glycerin tripalmitate
Tripalmitin
Trihexadecanoin
Glyceryl palmitate
Palmitin
Glyceryl trihexadecanoate
Triglyceride of palmitic acid
Glyceryl palmitic acid ester
Palmitic acid glyceride
Glycerol tris(palmitate)
Glyceryl tripalmitate
Trihexadecyl glycerol
Tristearin
Glyceryl tristearate
Stearin
Triglyceride of stearic acid
Glycerin tristearate
Glycerol tristearate
Triglycerol palmitostearate
Tri(palmitoyloxy)propane
Glyceryl palmitostearate
Palmitostearin
Glyceryl trin-hexadecanoate
Triglyceride of hexadecanoic acid
Hexadecanoyl glycerol
Glycerin trin-hexadecanoate
Glyceryl hexadecanoate
Glycerol trin-hexadecanoate
Triglycerol stearopalmitate
Glycerin tristearopalmitate
Glyceryl tristearopalmitate
Tristearo-palmitin
Glycerol trin-octadecanoate
Triglyceride of octadecanoic acid
Octadecanoyl glycerol

Glycerol tristearate is a solid, waxy substance at room temperature.
Glycerol tristearate is odorless and has a faint characteristic taste.
Glycerol tristearate has a white to off-white color.

CAS number: 555-43-1



APPLICATIONS


Glycerol tristearate, or tristearin, has various applications in different industries.
Here are some of its common applications:

Food Industry:
Glycerol tristearate is used as an emulsifier and stabilizer in food products.
Glycerol tristearate helps improve the texture and consistency of processed foods such as margarine, spreads, chocolate, confectionery, and baked goods.

Cosmetics and Personal Care:
Glycerol tristearate is utilized in cosmetics and personal care products for its emollient and moisturizing properties.
Glycerol tristearate can be found in creams, lotions, lipsticks, and other skincare formulations.

Pharmaceuticals:
Glycerol tristearate acts as a lubricant in the pharmaceutical industry, particularly in tablet formulations.
Glycerol tristearate aids in the easy release of tablets from molds and enhances their swallowability.

Industrial Lubricants:
Due to its lubricating properties, glycerol tristearate is used as a component in industrial lubricants and greases.
Glycerol tristearate helps reduce friction and wear between moving parts in machinery and equipment.

Candle Making:
Glycerol tristearate is commonly used in the production of candles.
Glycerol tristearate serves as a key ingredient in candle wax formulations, providing structure, stability, and a slow-burning characteristic.

Rubber and Plastics:
Glycerol tristearate acts as a release agent in the manufacturing of rubber and plastic products.
Glycerol tristearate prevents sticking of the material to molds during the production process.

Textile Industry:
Glycerol tristearate finds application in the textile industry as a softening agent and lubricant for fabrics.
Glycerol tristearate can improve the hand feel and flexibility of textiles, making them more comfortable to wear.

Metal Processing:
Glycerol tristearate is employed in metalworking processes as a lubricant and anti-weld agent.
Glycerol tristearate helps reduce friction during machining and prevents metal particles from sticking to tools and surfaces.


Glycerol tristearate is commonly used as an emulsifier and stabilizer in the food industry.
Glycerol tristearate helps maintain the texture and consistency of margarine and spreads.
Glycerol tristearate is used in chocolate production to improve viscosity and prevent fat bloom.

Glycerol tristearate serves as a vital ingredient in confectionery items like candies and chocolate coatings.
Glycerol tristearate is utilized in bakery products to enhance dough handling and improve crumb texture.

Glycerol tristearate is a key component in the formulation of lipstick, providing structure and texture.
Glycerol tristearate acts as a moisturizing agent in creams and lotions, helping to nourish the skin.
Glycerol tristearate is used in the production of soaps and cleansing bars to create a creamy lather.
Glycerol tristearate is employed in the pharmaceutical industry as a lubricant in tablet manufacturing.

Glycerol tristearate aids in the smooth release of tablets from molds and prevents sticking.
Glycerol tristearate finds application in the production of candles, providing a slow-burning and solid wax base.

Glycerol tristearate is used as a release agent in the manufacturing of rubber and plastic products.
Glycerol tristearate helps prevent adhesion and sticking of the material to molds and equipment.
Glycerol tristearate serves as an emollient in cosmetic formulations, providing a soft and smooth texture.

Glycerol tristearate is used in haircare products to improve manageability and add shine to the hair.
Glycerol tristearate finds application in the formulation of sunscreen products, contributing to their water resistance.

Glycerol tristearate is used in the production of industrial lubricants, reducing friction and wear in machinery.
Glycerol tristearate serves as a thickening agent in certain paint and coating formulations, improving their consistency.

Glycerol tristearate finds application in the textile industry as a softening agent for fabrics.
Glycerol tristearate is used in metalworking processes as a lubricant and anti-weld agent.
Glycerol tristearate finds application in the production of paper and paperboard, enhancing their printability and surface properties.
Glycerol tristearate is used in the formulation of adhesives and sealants, providing viscosity and stability.

Glycerol tristearate is employed in the production of plasticizers, improving the flexibility and workability of plastic materials.
Glycerol tristearate is used in the manufacturing of wax-based polishes for furniture and floors.
Glycerol tristearate finds application in the leather industry for conditioning and softening leather products.

Glycerol tristearate is utilized in the production of chewing gum to improve its texture and mouthfeel.
Glycerol tristearate is used in the formulation of lip balms and lip care products for its moisturizing properties.

Glycerol tristearate is employed as a binder in the production of pressed powders and cosmetic compacts.
Glycerol tristearate finds application in the manufacture of cold creams and ointments, providing emollient and occlusive properties.
Glycerol tristearate is used in the production of adhesives for improved tack and bond strength.

Glycerol tristearate serves as a plasticizer in the rubber industry, enhancing the flexibility and elasticity of rubber products.
Glycerol tristearate finds application in the production of gel capsules, enabling easy swallowing of medications and supplements.
Glycerol tristearate is used in the formulation of shaving creams and foams to provide lubrication and a smooth shaving experience.

Glycerol tristearate is employed in the production of printing inks for its viscosity and pigment dispersion properties.
Glycerol tristearate finds application in the textile printing industry as an auxiliary agent to improve color fastness and print quality.
Glycerol tristearate is used in the manufacture of wax-based crayons and colored pencils for their smooth application.

Glycerol tristearate serves as a release agent in the production of molded plastic products, ensuring easy demolding and preventing surface defects.
Glycerol tristearate finds application in the production of inkjet inks for its compatibility with dye and pigment dispersion.
Glycerol tristearate is used in the formulation of metal coatings to provide corrosion resistance and improve adhesion.
Glycerol tristearate is employed in the production of dietary supplements as a carrier for fat-soluble vitamins and nutrients.

Glycerol tristearate finds application in the formulation of polishes for shoes and leather goods, providing shine and protection.
Glycerol tristearate is used in the production of wax-based modeling compounds for arts and crafts.
Glycerol tristearate serves as a lubricant in wire and cable manufacturing, facilitating smooth wire drawing and reducing friction.
Glycerol tristearate is employed in the production of molded chocolates and pralines for their glossy appearance and snap texture.

Glycerol tristearate finds application in the production of solid oral dosage forms, such as sustained-release tablets and capsules.
Glycerol tristearate is used in the production of animal feeds as an energy source and binder for pellets.

Glycerol tristearate serves as a plasticizer in PVC (polyvinyl chloride) formulations, improving flexibility and processability.
Glycerol tristearate finds application in the production of thermal transfer ribbons for printing on labels and packaging materials.

Glycerol tristearate is used in the formulation of face masks and skincare products for its moisturizing and nourishing properties.
Glycerol tristearate is employed in the production of specialty waxes, such as investment casting waxes and dental waxes.



DESCRIPTION


Glycerol tristearate, also known as tristearin, is a chemical compound belonging to the ester group.
Its chemical formula is C57H110O6, and its systematic name is 1,2,3-trihydroxypropane tristearate.
Glycerol tristearate is formed by esterification of glycerol (a triol) with stearic acid (a long-chain saturated fatty acid).

In simpler terms, glycerol tristearate consists of three stearic acid molecules chemically linked to a glycerol molecule.
The stearic acid molecules provide the fatty nature to the compound, while the glycerol molecule acts as a backbone.
This combination results in a solid, waxy substance at room temperature.

Glycerol tristearate is a solid, waxy substance at room temperature.
Glycerol tristearate is odorless and has a faint characteristic taste.
Glycerol tristearate has a white to off-white color.

Glycerol tristearate is insoluble in water.
Glycerol tristearate is soluble in organic solvents such as ethanol and chloroform.

Glycerol tristearate has a high melting point, typically around 68-70°C.
Glycerol tristearate is a triglyceride composed of three stearic acid molecules and one glycerol molecule.

Glycerol tristearate is derived from natural sources such as animal fats and vegetable oils.
Glycerol tristearate is commonly found in various food products as a food additive and emulsifier.

Glycerol tristearate is used in the cosmetic industry for its emollient and moisturizing properties.
Glycerol tristearate is also utilized in the pharmaceutical industry as a lubricant in tablet formulations.
Glycerol tristearate has excellent stability and resistance to oxidation.
Glycerol tristearate exhibits good heat resistance and is often used in high-temperature applications.
Glycerol tristearate is a common ingredient in the production of candles and other wax-based products.

Glycerol tristearate is used as a release agent in the manufacturing of rubber and plastics.
Glycerol tristearate acts as a thickening agent in certain formulations, such as creams and lotions.

Glycerol tristearate can enhance the texture and mouthfeel of food products, providing a smooth and creamy sensation.
Glycerol tristearate is employed as a binder in the production of pressed powders and cosmetics.
Glycerol tristearate is biodegradable and environmentally friendly.

Glycerol tristearate is considered safe for use in various applications, including food and personal care products.
Glycerol tristearate has low toxicity and is not known to cause significant health risks.
Glycerol tristearate has good compatibility with other ingredients, making it versatile in formulation.

Glycerol tristearate has a long shelf life and can withstand storage and transportation conditions.
Glycerol tristearate is a valuable ingredient in the production of lubricants and greases.
Glycerol tristearate plays a crucial role in numerous industries, contributing to the functionality and quality of various products.



PROPERTIES


Chemical Formula: C57H110O6
Molecular Weight: 891.50 g/mol
Appearance: White to off-white solid
Odor: Odorless
Melting Point: Approximately 70-75°C (158-167°F)
Boiling Point: Decomposes before boiling
Density: 0.86 g/cm3
Solubility: Insoluble in water; soluble in organic solvents such as ethanol, ether, and chloroform
Refractive Index: 1.438 (at 20°C)
Flash Point: >200°C (>392°F)
Vapor Pressure: Negligible
Viscosity: High viscosity in molten state
pH: Neutral
Stability: Stable under normal conditions
Flammability: Non-flammable
Autoignition Temperature: Not applicable
Hydrogen Bonding: Exhibits hydrogen bonding due to the presence of hydroxyl groups
Emulsifying Properties: Acts as an emulsifier, aiding in the mixing of immiscible substances
Lubricating Properties: Provides lubrication and reduces friction between surfaces
Solidification Behavior: Forms a solid with a crystalline structure upon cooling



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air and ensure they are in a well-ventilated area.
If breathing difficulties persist, seek medical attention immediately.
Provide artificial respiration if necessary.


Skin Contact:

Remove any contaminated clothing and immediately rinse the affected area with plenty of water.
Gently wash the skin with mild soap and water.
If irritation occurs or persists, seek medical advice.
Apply a suitable moisturizer or skin cream to help restore skin moisture.


Eye Contact:

Flush the eyes gently with water for at least 15 minutes, ensuring to remove any contact lenses if present and easily removable.
Seek immediate medical attention and bring the product label or safety data sheet for reference.
Avoid rubbing the eyes to prevent further irritation or damage.


Ingestion:

Rinse the mouth thoroughly with water and drink plenty of water to dilute the product.
Do not induce vomiting unless instructed to do so by medical professionals.
Seek immediate medical attention and provide the medical personnel with detailed information about the product.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves, safety goggles, and a lab coat or protective suit, to minimize exposure.
Use respiratory protection, such as a dust mask or respirator, if handling the product in powdered or aerosol form.

Ventilation:
Ensure good ventilation in the working area to prevent the buildup of vapors or dust concentrations.
If necessary, use local exhaust ventilation or wear respiratory protection to control exposure levels.

Avoiding Contact:
Avoid direct contact with the skin, eyes, and clothing.
Handle the product with clean, dry tools or equipment to prevent contamination.

Storage and Handling:
Store Glycerol tristearate in a tightly sealed container in a cool, dry, and well-ventilated area.
Keep away from heat sources, open flames, sparks, and direct sunlight.
Prevent the entry of moisture or water into the storage container to maintain product quality.
Follow all relevant safety guidelines and regulations when handling the substance.


Storage:

Temperature:
Store Glycerol tristearate at room temperature, preferably between 15°C and 30°C (59°F and 86°F).

Container:
Use suitable containers, such as tightly sealed plastic or metal containers, to store the product.
Ensure the containers are labeled correctly with the product name, batch number, and hazard information.

Separation:
Store Glycerol tristearate away from incompatible substances, such as strong oxidizing agents or acids, to prevent chemical reactions.

Handling Precautions:
Avoid dropping or mishandling containers to prevent spills or breakages.
Use appropriate equipment, such as drum pumps or scoops, to transfer the product and minimize the risk of exposure.

Fire Safety:
Keep Glycerol tristearate away from potential ignition sources and flammable materials.
In the event of a fire involving the substance, use suitable extinguishing media, such as carbon dioxide or dry chemical powder.



SYNONYMS


Tristearin
Glyceryl tristearate
Glycerin tristearate
Glyceryl tristearin
1,2,3-Propanetriol tristearate
Glycerol tristearin
Glycerol tristearyl ester
Triglyceride tristearin
Triglycerol tristearate
Tri(stearoyl) glycerol
Glycerin trioctadecanoate
Triglyceride of stearic acid
Glycerol trioctadecanoate
Triglyceride 50 C18:0
Glycerin trioctadecyl ester
Glyceryl tristearyl ether
Glycerin trioctadecyl ether
Triglyceride stearic acid ester
Glycerol trioctadecyl ester
Triglycerol trioctadecanoate
Glycerol trioctadecyl ether
Tristearate of glycerol
Glycerol ester of stearic acid
Glyceryl trioctadecanoate
Triglyceride of octadecanoic acid
Tri(stearinyl) glycerol
Triglyceride C18:0
Glyceryl tristearylate
Glycerol trioctadecanoic ester
Triglycerol trioctadecyl ester
Glycerol trioctadecylate
Tristearoylglycerol
Stearic acid triglyceride
Glycerin tristearylate
Glyceryl tristearate ester
Triglyceride of stearin
Glycerol trioctadecanoate ester
Tri(stearoyloxy) glycerol
Glycerol trioctadecyl stearate
Triglycerol trioctadecyl stearate
Glyceryl trioctadecanoate ester
Tristearin glyceride
Glycerin trioctadecanoate ester
Tri(stearoyloxy)glycerol
Glycerol trioctadecyl stearate ester
Triglycerol trioctadecyl stearate ester
Glycerol tristearate triglyceride
Tristearin triester
Glycerin trioctadecyl stearate triglyceride
Tri(stearoyloxy) glyceryl ester

Nom INCI : GLYCERYL ASCORBATE Ses fonctions (INCI) Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la rancidité Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau

GLYCERYL CAPRATE, N° CAS : 26402-22-2, Nom INCI : GLYCERYL CAPRATE, Nom chimique : Decanoic acid, monoester with glycerol, N° EINECS/ELINCS : 247-667-6, Ses fonctions (INCI), Emollient : Adoucit et assouplit la peau

GLYCERYL CAPRYLATE, N° CAS : 26402-26-6, Nom INCI : GLYCERYL CAPRYLATE. Nom chimique : Octanoic acid, monoester with glycerol, N° EINECS/ELINCS : 247-668-1. Ses fonctions (INCI). Emollient : Adoucit et assouplit la peau. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

Nom INCI : GLYCERYL CAPRYLATE/CAPRATE Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

GLYCERYL COCOATE, N° CAS : 61789-05-7. Nom INCI : GLYCERYL COCOATE, N° EINECS/ELINCS : 263-027-9. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau, Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

Di(isooctadecanoic) acid, diester with glycerol; GLYCERYL DIISOSTEARATE, N° CAS : 68958-48-5, Nom INCI : GLYCERYL DIISOSTEARATE, N° EINECS/ELINCS : 273-368-5. Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau, Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile). Opacifiant : Réduit la transparence ou la translucidité des cosmétiques

DESCRIPTION:
Glyceryl diacetate (Diacetin) is a food additive with the E number E1517.
This diglyceride is more generally known as diacetin.
Glyceryl diacetate (Diacetin) is the diester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.

CAS Number, 25395-31-7
EC Number, 246-941-2


SYNONYMS OF GLYCERYL DIACETATE (DIACETIN):
Diacetin; Glycerol diacetate, 1,2,3-Propanetriol, 1,2-diacetate; 2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate; 1,2-Diacetin; Acetin, 1,2-di-; Acetic acid, diglyceride; (Hydroxymethyl)ethylene acetate; 1,2-Diacetylglycerol; 2,3-Diacetin; 2,3-Diacetoxypropan-1-ol; NSC 2348, 1,2,3-Propanetriol,diacetate;Acetin,di-;Diacetin;Glycerol diacetate;Glyceryl diacetate;Diacetylglycerol;Glycerine diacetate;Glycerin diacetate;Estol 1583;Estol 1582;Diacetain glycerol;1300-63-6;29860-16-0;1202865-19-7, Glycerol Diacetate; 1,2,3-Propanetriol, Diacetate;
Diacetylglycerol; Glycerin diacetate; Glycerine Diacetate; Glyceryl Diacetate; Glycerol 1,3-diacetate; 2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate; 1,3-Di(acetato) de glicerol (Spanish); 1,3-di(acétate) de glycerol (French); GLYCERYL DIACETATE;Glycerin diacetate;GLYCEROL DIACETATE;Glycerol 1,3-diacetate;3-Hydroxypropane-1,2-diyl diacetate;2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate;di-aceti;DIACETIN;Carset 555;Carset 533



Glycerine (glycerin, glycerol, or 1,2,3-propanetriol) is the simplest trihedric alcohol.
Pure glycerine, with a specific gravity of 1.26, is a colorless, odorless, sweet, viscous liquid melting at 17.8 C boiling at 290 C.
Glyceryl diacetate (Diacetin) decomposes at boiling point and produce corrosive fumes of acrolein.

Glyceryl diacetate (Diacetin) is miscible in water and forms a solution in any proportion.
Glyceryl diacetate (Diacetin) is also soluble alcohol but only partially soluble in common organic solvents such as ether and ethyl acetate.
Glyceryl diacetate (Diacetin) resists freezing.

Glyceryl diacetate (Diacetin) is hygroscopic, which favors as a humectant to retain moisture in cosmetics.
Glyceryl diacetate (Diacetin) reacts violently with acetic anhydrides in the presence of a catalyst.
Glyceryl diacetate (Diacetin) is obtained as a byproduct when fats and oils are hydrolyzed to yield fatty acids or soaps.

Glyceryl diacetate (Diacetin) is also commercially synthesized from propylene (Dow Chemical).
Glyceryl diacetate (Diacetin) can also be obtained based on a proprietary fermentation processing.
Glycerol is widely used; as a solvent, food additive, sweetening agent and emollient and emulcent with magnesium sulphate used in the treatment of septic wounds and boils; in the manufacture of alkyd resin, cellophane, ester gums, plasticizer, dynamite, nitroglycerine, cosmetics, liquid soap, perfume and toothpaste (good solubility and taste give glycerine an edge on sorbitol in toothpastes, which are estimated to make up almost one-third of glycerine's market in personal care products); as a component of antifreeze mixtures; to keep fabrics pliable, to preserve printing on cotton, to keep frost from windshields; as a source of nutrients for fermentation cultures in the production of antibiotics; as a preservative in some pharmaceutical and biological preparations and in non-alcoholic extracts and tinctures.

Glyceryl diacetate (Diacetin) has many other applications.









Glyceryl diacetate (Diacetin) is Clear, colourless, hygroscopic, somewhat oily liquid with a slight, fatty odour, consisting predominantly of a mixture of the 1,2- and 1,3-diacetates of glycerol, with minor amounts of the mono- and tri-esters

Glyceryl diacetate (Diacetin) is a colorless, viscous and odorless liquid with a high boiling point.
Glycerol diacetate (Diacetin) is typically a mixture of two isomers, 1,2-glyceryl diacetate and 1,3-glyceryl diacetate.

USES OF GLYCEROL DIACETATE (DIACETIN):
Glycerol diacetate (Diacetin) is Used in the food industry, it gives dishes a buttery taste.
Diacetin is also used as a solvent, plasticizer, and softening agent.

Diacetin has been used to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated with aqueous colloidal polymer dispersions
Diacetin is used as a solvent, plasticizer, and softening agent.

Glycerol diacetate (Diacetin), triacetate ester of glycerol, is a clear, combustible and oily liquid with a bitter taste and a fatty odor.
Glycerol diacetate (Diacetin) is slightly soluble in water but soluble in alcohol and ether.

Glycerol diacetate (Diacetin) has properties of both glycerol and acetate.
Diacetin (CAS RN: 25395-31-7) and nonoacetin (CAS RN: 26446-35-5) are glycerin diacetate and glycerin monoacetate respectively.

Glycerol diacetate (Diacetin) is found in some food like butter as it is used as a food additive for the solvency of flavourings for the function of humectant.
Glycerol diacetate (Diacetin) is used in perfumery and cosmetics for these applications.

Glycerol diacetate (Diacetin) is used as an antifungal agent in external medicine for topical treatment of superficial fungal infections of the skin.
Glycerol diacetate (Diacetin) is applied to cigarette filter as a plasticizer.
Glycerol diacetate (Diacetin) is used as a gelatinizing agent in explosives.


CHEMICAL AND PHYSICAL PROPERTIES OF GLYCEROL DIACETATE (DIACETIN):
Chemical formula, C7H12O5
Molar mass, 176.168 g•mol−1
Melting point, −30 °C (−22 °F; 243 K)
Boiling point, 280 °C (536 °F; 553 K)
CAS Number, 25395-31-7 (mixture)
102-62-5 (1,2)
105-70-4 (1,3)
3D model (JSmol), Interactive image
ChemSpider, 59412 (1,2)60286 (1,3)
ECHA InfoCard, 100.042.659
EC Number, 246-941-2
E number, E1517
grade
technical grade
Quality Level
100
vapor density
6.1 (vs air)
vapor pressure
form
liquid
concentration
50%
refractive index
n20/D 1.440 (lit.)
solubility
alcohol: soluble(lit.)
benzene: soluble(lit.)
carbon disulfide: insoluble (practically)(lit.)
diethyl ether: soluble(lit.)
water: soluble(lit.)

density
1.17 g/mL at 25 °C (lit.)
Molecular Weight：
176.17
Exact Mass：
176.068466
HScode：
2918199090
PSA：
72.83000
XLogP3：
-0.52650
Appearance：
absorption near colorless, transparent oily liquid
Density：
1.2±0.1 g/cm3
Melting Point：
-30 °C
Boiling Point：
259 °C
Flash Point：
90.7±11.7 °C
Refractive Index：
1.444
Water Solubility：
Soluble in water, alcohol, ether, benzene
Storage Conditions：
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure：
Vapor Density：
6.1 (vs air)
PHYSICAL STATE, clear oily liquid
MELTING POINT, -30 C
BOILING POINT, 259 C
SPECIFIC GRAVITY, 1.18 - 1.195
SOLUBILITY IN WATER, slightly soluble (soluble alcohol; slightly soluble in ether, carbon disulfide; insoluble in benzene)
NFPA RATINGS, Health: 1 Flammability: 1 Reactivity: 0
STABILITY, Stable under ordinary conditions
Density, 1.19
Boiling Point, 250°C to 280°C (decomposition)
Flash Point, 141°C (285°F)
Refractive Index, 1.444
Quantity, 250 g
Beilstein, 1706903
Sensitivity, Hygroscopic
Merck Index, 14,2961
Solubility Information, Fully miscible in water.
Formula Weight, 176.17
Percent Purity, ≈50%
Grade, Technical
Assay, remainder triacetin and monoacetin
Chemical Name or Material, Diacetin, mixed isomers
Physical State :
Liquid
Storage :
Desiccate at room temperature
Density :
1.17 g/mL at 25° C (lit.)
Refractive Index :
n20D 1.440 (lit.)
-30 °C
Boiling point:
280 °C
Density
1.17 g/mL at 25 °C (lit.)
vapor density
6.1 (vs air)
vapor pressure
refractive index
n20/D
Melting point, -30 °C
Boiling point, 280 °C
Density, 1.17 g/mL at 25 °C (lit.)
vapor density, 6.1 (vs air)
vapor pressure, refractive index, n20/D 1.440(lit.)
Flash point, >230 °F
storage temp., Inert atmosphere,Room Temperature
solubility, alcohol: soluble(lit.)
form, Liquid
color, Clear colorless
PH, 5-6 (50g/l, H2O, 20℃)
Odor, at 100.00 %. very mild alcoholic
Odor Type, alcoholic
Water Solubility, Soluble in water, alcohol, ether, benzene
Sensitive, Hygroscopic
Merck, 14,2961
BRN, 1706903
LogP, -0.640
Indirect Additives used in Food Contact Substances, GLYCEROL DIACTATE
FDA 21 CFR, 177.1200
CAS DataBase Reference, 25395-31-7(CAS DataBase Reference)
EWG's Food Scores, 1
FDA UNII, GJ0544W99Q
NIST Chemistry Reference, 1,2,3-Propanetriol, diacetate(25395-31-7)
EPA Substance Registry System, 1,2,3-Propanetriol, diacetate (25395-31-7)



SAFETY INFORMATION ABOUT GLYCERYL DIACETATE (DIACETIN):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

DESCRIPTION:

Glyceryl Diacetate (Diacetin) is a food additive with the E number E1517.
Glyceryl Diacetate (Diacetin) is more generally known as diacetin.
Glyceryl Diacetate (Diacetin) is the diester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.

CAS Number, 25395-31-7
EC Number, 246-941-2
Linear Formula:: (CH3COOCH2)2CHOH


SYNONYMS OF GLYCERYL DIACETATE (DIACETIN):
Glycerol diacetate 1,2,3-Propanetriol Diacetate, Diacetin, Glycerol Diacetate, E1517,glyceryl diacetate, 1,2-diacetin, glycerol diacetate, 1,2,3-propanetriol, diacetate, 3-hydroxypropane-1,2-diyl diacetate, glycerol 1,2-diacetate, 1,2-diacylglycerol, 2,3-diacetin, 1,2-diacetylglycerol, acetin, di,102-62-5,1,2,3-Propanetriol, diacetate,3-Hydroxypropane-1,2-diyl diacetate,1,2-Diacetin,1,2-Diacetylglycerol,Glycerol diacetate,1,2-diacylglycerol,3-DiacetinGlycerol 1,2-diacetate,Glyceryl diacetate,(2-acetyloxy-3-hydroxypropyl) acetate,Acetin, di-,(Hydroxymethyl)ethylene acetate,Acetin, 1,2-di-,1,2,3-Propanetriol, 1,2-diacetate,2,3-Diacetoxypropan-1-ol,acid, diglyceride,NSC 2348,glyceryl 1,2-diacetate,1-(acetyloxy)-3-hydroxypropan-2-yl acetate,NSC-2348,Glycerin diacetate,9W955270ZW,Glycerine diacetate,Estol 1582,Estol 1583,EINECS 246-941-2,1775840,UNII-GJ0544W99Q,AI3-00676,CCRIS 9354,CCRIS 9462,UNII-9W955270ZW,Diacetyl glycerine,Acetin,2-di-,2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate,DL-1,2-DIACETIN,WLN: 1VOY1Q1OV1,SCHEMBL77521,3-02-00-00331 (Beilstein Handbook Reference),1,2-Diacetin (~90%),1,2-DIACETIN, DL,DAG 4:0,DTXSID70883105,NSC2348,(+/-)-Glycerol 1,2-diacetate,CHEBI:173246,GJ0544W99Q,1,3-Propanetriol, 1,2-diacetate,3-Hydroxypropane-1,2-diyldiacetate,AKOS006273209,Diacetin (Mixture) (Technical Grade),1,2-DIACETIN, (+/-)-,(1-acetyloxy-3-hydroxypropan-2-yl)acetate,CS-0236630,FT-0624585,NS00013555,EN300-1720881,A877596,Q24300357,Z1198148277,2-(Acetyloxy)-1-(hydroxymethyl)ethyl acetate, AldrichCPR,101364-64-1

Glyceryl Diacetate (Diacetin) is widely used as plasticizer.
Glyceryl Diacetate (Diacetin) has been used to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated with aqueous colloidal polymer dispersions.


Glyceryl Diacetate (Diacetin) is a colorless, viscous and odorless liquid with a high boiling point.
Glycerol diacetate is typically a mixture of two isomers, 1,2-glyceryl diacetate and 1,3-glyceryl diacetate.



APPLICATIONS OF GLYCERYL DIACETATE (DIACETIN):
Glyceryl Diacetate (Diacetin) has been used to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated with aqueous colloidal polymer dispersions

Clear, colourless, hygroscopic, somewhat oily liquid with a slight, fatty odour, consisting predominantly of a mixture of the 1,2- and 1,3-diacetates of glycerol, with minor amounts of the mono- and tri-esters

A diglyceride resulting from the formal condensation of any two of the hydroxy groups of glycerol with the carboxy groups of two molecules of acetic acid (either R1 = H and R2 = Ac, or R1 = Ac and R2 = H).
Glyceryl Diacetate (Diacetin) is widely used as plasticizer.

Glyceryl Diacetate (Diacetin) has been used to design and evaluate gliclazide push-pull osmotic pump (PPOP) coated with aqueous colloidal polymer dispersions.
Food additive as a solvent for other additives, especially flavors.
Glyceryl Diacetate (Diacetin) is obtained from acetic acid and glycerol.

Glyceryl Diacetate (Diacetin) is a high-quality, clear ester liquid used as a solvent and carrier.
Glyceryl Diacetate (Diacetin) is used in chemical manufacturing and other food applications.


Glyceryl Diacetate (Diacetin), triacetate ester of glycerol, is a clear, combustible and oily liquid with a bitter taste and a fatty odor.
Glyceryl Diacetate (Diacetin) is slightly soluble in water but soluble in alcohol and ether.

Glyceryl Diacetate (Diacetin) has properties of both glycerol and acetate.
Glyceryl Diacetate (Diacetin) (CAS RN: 25395-31-7) and nonoacetin (CAS RN: 26446-35-5) are glycerin diacetate and glycerin monoacetate respectively.
Glyceryl Diacetate (Diacetin) is found in some food like butter as it is used as a food additive for the solvency of flavourings for the function of humectant.

Glyceryl Diacetate (Diacetin) is used in perfumery and cosmetics for these applications.
Glyceryl Diacetate (Diacetin) is used as an antifungal agent in external medicine for topical treatment of superficial fungal infections of the skin.
Glyceryl Diacetate (Diacetin) is applied to cigarette filter as a plasticizer.
Glyceryl Diacetate (Diacetin) is used as a gelatinizing agent in explosives.


Glyceryl Diacetate (Diacetin) (glycerin, glycerol, or 1,2,3-propanetriol) is the simplest trihedric alcohol.
Pure glycerine, with a specific gravity of 1.26, is a colorless, odorless, sweet, viscous liquid melting at 17.8 C boiling at 290 C.
Glyceryl Diacetate (Diacetin) decomposes at boiling point and produce corrosive fumes of acrolein.

Glyceryl Diacetate (Diacetin) is miscible in water and forms a solution in any proportion.
Glyceryl Diacetate (Diacetin) is also soluble alcohol but only partially soluble in common organic solvents such as ether and ethyl acetate.
Glyceryl Diacetate (Diacetin) resists freezing.

Glyceryl Diacetate (Diacetin) is hygroscopic, which favors as a humectant to retain moisture in cosmetics.
Glyceryl Diacetate (Diacetin) reacts violently with acetic anhydrides in the presence of a catalyst.
Glyceryl Diacetate (Diacetin) is obtained as a byproduct when fats and oils are hydrolyzed to yield fatty acids or soaps.

Glyceryl Diacetate (Diacetin) is also commercially synthesized from propylene (Dow Chemical).
Glyceryl Diacetate (Diacetin) can also be obtained based on a proprietary fermentation processing.
Glyceryl Diacetate (Diacetin) is widely used; as a solvent, food additive, sweetening agent and emollient and emulcent with magnesium sulphate used in the treatment of septic wounds and boils; in the manufacture of alkyd resin, cellophane, ester gums, plasticizer, dynamite, nitroglycerine, cosmetics, liquid soap, perfume and toothpaste (good solubility and taste give glycerine an edge on sorbitol in toothpastes, which are estimated to make up almost one-third of glycerine's market in personal care products); as a component of antifreeze mixtures; to keep fabrics pliable, to preserve printing on cotton, to keep frost from windshields; as a source of nutrients for fermentation cultures in the production of antibiotics; as a preservative in some pharmaceutical and biological preparations and in non-alcoholic extracts and tinctures. It has many other applications.


CHEMICAL AND PHYSICAL PROPERTIES OF GLYCERYL DIACETATE (DIACETIN)
Chemical formula, C7H12O5
Molar mass, 176.168 g•mol−1
Melting point, −30 °C (−22 °F; 243 K)
Boiling point, 280 °C (536 °F; 553 K)
CAS Number:
25395-31-7
Molecular Weight:
176.17
EC Number:
246-941-2
E No., E 1517
Chemical Family
Esters,
Glycerol Esters & Derivatives
Chemical Name
Glyceryl Diacetate
Ingredient Name
Glyceryl Diacetate
Base Chemicals Functions
Solvent
Food Ingredients Functions
Carrier,
Solvent
Technologies
Base Chemicals & Intermediates,
Food Ingredients
Product Families
Food Ingredients — Functional Additives
Carriers & Bulking Aids
Base Chemicals & Intermediates — Solvents
Esters
Color, max. 15, HU
Acidity (as acetic acid), max. 0.03, %
Saponification Value, 605 - 635
Water Content, max. 0.2
Specific Gravity (at 20/20°C), 1.175 - 1.195
Molecular Weight
176.17 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3
-0.3
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
5
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
6
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
176.06847348 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
176.06847348 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
72.8Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
12
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
165
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
1
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
grade
technical grade
Quality Level
100
vapor density
6.1 (vs air)
vapor pressure
<1 mmHg ( 20 °C)
form
liquid
concentration
50%
refractive index
n20/D 1.440 (lit.)
solubility
alcohol: soluble(lit.)
benzene: soluble(lit.)
carbon disulfide: insoluble (practically)(lit.)
diethyl ether: soluble(lit.)
water: soluble(lit.)

density
1.17 g/mL at 25 °C (lit.)
SMILES string
CC(=O)OCC(O)COC(C)=O.CC(=O)OCC(CO)OC(C)=O
InChI
1S/2C7H12O5/c1-5(8)11-3-7(10)4-12-6(2)9;1-5(9)11-4-7(3-8)12-6(2)10/h7,10H,3-4H2,1-2H3;7-8H,3-4H2,1-2H3
InChI key
TWSUHSVPDUPKDH-UHFFFAOYSA-N
Composition, C7H12O5
CAS, 25395-31-7
Melting Point, -30 C
Density, 1.184 g/ml
Molecular Weight, mol. wt. = 176.17
Refractive Index, 1.44
Boiling Point, 259 C
CAS, 25395-31-7
Boiling Point, 250°C to 280°C (decomposition)
Molecular Formula, C7H12O5
MDL Number, MFCD00008717
Beilstein, 1706903
Merck Index, 14,2961
Solubility Information, Fully miscible in water.
Percent Purity, ≈50%
Chemical Name or Material, Diacetin, mixed isomers
Flash Point, 141°C (285°F)
Refractive Index, 1.444
Quantity, 250 g
Sensitivity, Hygroscopic
Synonym, glyceryl diacetate, 1,2-diacetin, glycerol diacetate, 1,2,3-propanetriol, diacetate, 3-hydroxypropane-1,2-diyl diacetate, glycerol 1,2-diacetate, 1,2-diacylglycerol, 2,3-diacetin, 1,2-diacetylglycerol, acetin, di
Formula Weight, 176.17
Grade, Technical
Assay, remainder triacetin and monoacetin
Melting point, -30 °C
Boiling point, 280 °C
Density, 1.17 g/mL at 25 °C (lit.)
vapor density, 6.1 (vs air)
vapor pressure, <1 mm Hg ( 20 °C)
refractive index, n20/D 1.440(lit.)
Flash point, >230 °F
storage temp., Inert atmosphere,Room Temperature
solubility, alcohol: soluble(lit.)
form, Liquid
color, Clear colorless
PH, 5-6 (50g/l, H2O, 20℃)
Odor, at 100.00 %. very mild alcoholic
Odor Type, alcoholic
Water Solubility, Soluble in water, alcohol, ether, benzene
Sensitive, Hygroscopic
Merck, 14,2961
BRN, 1706903
LogP, -0.640
Indirect Additives used in Food Contact Substances, GLYCEROL DIACTATE
FDA 21 CFR, 177.1200
CAS DataBase Reference, 25395-31-7(CAS DataBase Reference)
EWG's Food Scores, 1
FDA UNII, GJ0544W99Q
NIST Chemistry Reference, 1,2,3-Propanetriol, diacetate(25395-31-7)
EPA Substance Registry System, 1,2,3-Propanetriol, diacetate (25395-31-7)



SAFETY INFORMATION ABOUT GLYCERYL DIACETATE (DIACETIN):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

GLYCERYL DILAURATE, N° CAS : 27638-00-2. Nom INCI : GLYCERYL DILAURATE. N° EINECS/ELINCS : 248-586-9. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

N° CAS : 26657-95-4 Nom INCI : GLYCERYL DIPALMITATE N° EINECS/ELINCS : 247-886-7 Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

GLYCERYL DISTEARATE, N° CAS : 1323-83-7, Nom INCI : GLYCERYL DISTEARATE, N° EINECS/ELINCS : 215-359-0, Ses fonctions (INCI): Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Emollient : Adoucit et assouplit la peau. DG(18:0/18:0/0:0)[rac] 1,2-dioctadecanoylglycerol 1,2-Dioctadecanoyl-rac-glycerol 1,2-Distearin 1,2-Distearoyl-rac-glycerol 1323-83-7 [RN] 1730305 215-359-0 [EINECS] 256-941-4 [EINECS] 3-Hydroxy-1,2-propandiyl-dioctadecanoat [German] [ACD/IUPAC Name] 3-Hydroxy-1,2-propanediyl dioctadecanoate [ACD/IUPAC Name] 3-Hydroxypropane-1,2-diyl dioctadecanoate 51063-97-9 [RN] Dioctadécanoate de 3-hydroxy-1,2-propanediyle [French] [ACD/IUPAC Name] Distearoylglycerol Distearoylglycerol mixed isomers DL-1,2-Distearin glycerol distearate GLYCERYL 1,2-DISTEARATE GLYCERYL 1,2-DISTEARATE, (S)- GLYCERYL DISTEARATE MFCD00066515 Octadecanoic acid 1,1'-[1-(hydroxymethyl)-1,2-ethanediyl] ester Octadecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester [ACD/Index Name] Octadecanoic acid, 2-hydroxy-1-[[(1-oxooctadecyl)oxy]methyl]ethyl ester rac-1,2-Distearoylglycerol rac-Glycerol 1,2-distearate (1)-1-(Hydroxymethyl)ethane-1,2-diyl distearate Distearin (±)-1,2-DISTEAROYLGLYCEROL (3-hydroxy-2-octadecanoyloxypropyl) octadecanoate [10567-21-2] [1188-58-5] [1323-83-7] [51063-97-9] 1,2-dioctadecanoyl-sn-glycerol 1,2-Di-O-hexadecanoylglycerol 1,2-Distearoyl-L-glycerol 1,2-distearoyl-sn-glycerol 10567-21-2 [RN] 1-hydroxy-3-(octadecanoyloxy)propan-2-yl octadecanoate 2-Hydroxy-1-[(stearoyloxy)methyl]ethyl stearate 3-Hydroxypropane-1,2-diyl distearate a,b-Distearin Cithrol EDS D-7500 D-7502 distearic acid, diester with glycerol Glycerol 1,2-dioctadecanoate Glycerol 1,2-distearate L-1,2-Distearin Octadecanoic acid 1-(hydroxymethyl)-1,2-ethanediyl ester Octadecanoic acid 2-hydroxy-1-octadecanoyloxy-ethyl ester Octadecanoic acid, diester with 1,2,3-propanetriol Octadecanoic acid,1,1'-[1-(hydroxymethyl)-1,2-ethanediyl] ester Octadecanoic acid,1,1'-[1-(hydroxymethyl)-1,2-ethanediyl]ester

GLYCERYL GLUCOSIDE, N° CAS : 22160-26-5 / 100402-60-6, Nom INCI : GLYCERYL GLUCOSIDE, Nom chimique : alpha-D-Glucopyranoside, 2-Hydroxy-1-(Hydroxymethyl)ethyl, N° EINECS/ELINCS : - / 309-496-6. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI) : Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Agent d'entretien de la peau : Maintient la peau en bon état

GLYCERYL ISOSTEARATE. N° CAS : 66085-00-5 / 32057-14-0. Nom INCI : GLYCERYL ISOSTEARATE. N° EINECS/ELINCS : 266-124-4. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

GLYCERYL LACTATE, N° CAS : 26855-41-4. Nom INCI : GLYCERYL LACTATE. Nom chimique : Propanoic acid, 2-hydroxy-, monoester with 1,2,3-propanetrio1

GLYCERYL LAURATE, N° CAS : 27215-38-4 / 142-18-7. Nom INCI : GLYCERYL LAURATE. N° EINECS/ELINCS : 248-337-4 / 205-526-6. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau. Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)

PEG-12 Glyceryl laurate; Polyoxyethyleneglycerol, monolaurate; Polyoxyethylene (12) glyceryl laurate cas no: 51248-32-9

Glyceryl monooleate (Gliseril monooleat) IUPAC Name 2,3-dihydroxypropyl (Z)-octadec-9-enoate Glyceryl monooleate (Gliseril monooleat) InChI InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9- Glyceryl monooleate (Gliseril monooleat) InChI Key RZRNAYUHWVFMIP-KTKRTIGZSA-N Glyceryl monooleate (Gliseril monooleat) Canonical SMILES RZRNAYUHWVFMIP-KTKRTIGZSA-N Glyceryl monooleate (Gliseril monooleat) Canonical SMILES CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)O Glyceryl monooleate (Gliseril monooleat) Isomeric SMILES CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CO)O Glyceryl monooleate (Gliseril monooleat) Molecular Formula C21H40O4 Glyceryl monooleate (Gliseril monooleat) CAS 111-03-5 Glyceryl monooleate (Gliseril monooleat) Deprecated CAS 30836-40-9, 33978-07-3, 925-14-4 Glyceryl monooleate (Gliseril monooleat) European Community (EC) Number 203-827-7 Glyceryl monooleate (Gliseril monooleat) NSC Number 406285 Glyceryl monooleate (Gliseril monooleat) JECFA Number 919 Glyceryl monooleate (Gliseril monooleat) FEMA Number 2526 Glyceryl monooleate (Gliseril monooleat) DSSTox Substance ID DTXSID3027875 Glyceryl monooleate (Gliseril monooleat) Physical Description DryPowder; Liquid; OtherSolid Glyceryl monooleate (Gliseril monooleat) Color/Form PLATES FROM ETHANOL Glyceryl monooleate (Gliseril monooleat) Odor SWEET Glyceryl monooleate (Gliseril monooleat) Taste FATTY TASTE Glyceryl monooleate (Gliseril monooleat) Boiling Point 238-240 °C AT 3 MM HG Glyceryl monooleate (Gliseril monooleat) Melting Point 35.0 °C Glyceryl monooleate (Gliseril monooleat)Solubility INSOL IN WATER; SOL IN ETHANOL, ETHER, CHLOROFORM Glyceryl monooleate (Gliseril monooleat) Density 0.9420 @ 20 °C/4 °C Glyceryl monooleate (Gliseril monooleat) Refractive Index INDEX OF REFRACTION: 1.4626 @ 40 °C/D Glyceryl monooleate (Gliseril monooleat) Collision Cross Section 202.8 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)] Glyceryl monooleate (Gliseril monooleat) Other Experimental Properties MELTING POINT: 32 °C (UNSTABLE) /PRIMARY BETA FORM/; 35.5 °C (STABLE) /BETA FORM/ Glyceryl monooleate (Gliseril monooleat) Molecular Weight 356.5 g/mol Glyceryl monooleate (Gliseril monooleat) XLogP3 6.5 Glyceryl monooleate (Gliseril monooleat) Hydrogen Bond Donor Count 2 Glyceryl monooleate (Gliseril monooleat) Hydrogen Bond Acceptor Count 4 Glyceryl monooleate (Gliseril monooleat) Rotatable Bond Count 19 Glyceryl monooleate (Gliseril monooleat) Exact Mass 356.29266 g/mol Glyceryl monooleate (Gliseril monooleat) Monoisotopic Mass 356.29266 g/mol Glyceryl monooleate (Gliseril monooleat) Topological Polar Surface Area 66.8 Ų Glyceryl monooleate (Gliseril monooleat) Heavy Atom Count 25 Glyceryl monooleate (Gliseril monooleat) Formal Charge 0 Glyceryl monooleate (Gliseril monooleat) Complexity 315 Glyceryl monooleate (Gliseril monooleat) Isotope Atom Count 0 Glyceryl monooleate (Gliseril monooleat) Defined Atom Stereocenter Count 0 Glyceryl monooleate (Gliseril monooleat) Undefined Atom Stereocenter Count 1 Glyceryl monooleate (Gliseril monooleat) Defined Bond Stereocenter Count 1 Glyceryl monooleate (Gliseril monooleat) Undefined Bond Stereocenter Count 0 Glyceryl monooleate (Gliseril monooleat) Covalently-Bonded Unit Count 1 Glyceryl monooleate (Gliseril monooleat) Compound Is Canonicalized Yes Glyceryl monooleate (Gliseril monooleat) is a polar lipid that can exist in various liquid crystalline phases in the presence of different amounts of water. It is regarded as a permeation enhancer due to its amphiphilic property. Various phases of Glyceryl monooleate (Gliseril monooleat)/solvent system containing sodium fluorescein were prepared to compare permeability using confocal laser scanning microscopy (CLSM). Glyceryl monooleate (Gliseril monooleat) was melted in a vial in a water bath heated to 45 °C. Propylene glycol and hexanediol were homogeneously dissolved in the melted Glyceryl monooleate (Gliseril monooleat). Sodium fluorescein in aqueous solution was diluted to various ratios and thoroughly mixed by an ultrasonic homogenizer. Each Glyceryl monooleate (Gliseril monooleat)/Solvent system with fluorescein was applied onto the epidermal side of excised pig skin and incubated overnight. CLSM was performed to observe how the Glyceryl monooleate (Gliseril monooleat)/solvent system in its different phases affect skin permeability. Cubic and lamellar phase formulations enhanced the fluorescein permeation through the stratum corneum. A solution system had the weakest permeability compared to the other two phases. Due to the amphiphilic nature of Glyceryl monooleate (Gliseril monooleat), cubic and lamellar phases might reduce the barrier function of stratum corneum which was observed by CLSM as fluorescein accumulated in the dermis. Based on the results, the glyceryl monooleate lyotropic mixtures could be applied to enhance skin permeation in various topical and transdermal formulations.Glyceryl monooleate (Gliseril monooleat) is a well-known molecule commonly used as an emulsifying agent, biocompatible controlled-release material, and a food additive. It is considered as a nontoxic, biodegradable, and biocompatible material classified as “generally recognized as safe” (GRAS). It is included in the FDA Inactive Ingredients Guide and present in nonparenteral medicines in the United Kingdom.Glyceryl monooleate (Gliseril monooleat) is a polar lipid with the ability to form various liquid crystalline phases in the presence of different amounts of water. In the presence of a small amount of water, Glyceryl monooleate (Gliseril monooleat) forms reversed micelles characterized by an oily texture. As more water is added, a mucous-like system is formed that corresponds to the lamellar phase. A large isotropic phase region dominates when more water is added (20 ∼ 40%). This phase, known as the cubic phase, is highly viscous. In addition, the temperature and ratio of weight to water plays a role in the various phases of Glyceryl monooleate (Gliseril monooleat). In the presence of high amounts of water in temperatures ranging from 20 ∼ 70 °C, the cubic phase might exist in a stable condition. The cubic phase is said to be bicontinuous since it consists of a curved bilayer extending in three dimensions, separating two congruent water channel networks. The water pore diameter is about 5 nm when the cubic phase is fully swollen. The presence of a lipid and an aqueous domain gives special properties to the cubic phase such as the ability to solubilize hydrophilic, hydrophobic, and amphiphilic substances .Previous research has demonstrated that the liquid crystalline phases of Glyceryl monooleate (Gliseril monooleat) such as the cubic and reversed hexagonal phase, increased transdermal drug delivery. The advantages of the formulations for transdermal drug delivery system might include biocompatibility and the ability to self-assemble their structure. The cubic phase of Glyceryl monooleate (Gliseril monooleat) can be dispersed in a water-rich environment and form a dispersion containing nanometer-sized particles. Glyceryl monooleate (Gliseril monooleat)'s interaction with phospholipid bilayers might suggest why it is known as a permeation enhancer.In the current study, effects of various formulations of Glyceryl monooleate (Gliseril monooleat)/water system on skin permeability were evaluated using Franz-diffusion cells and confocal laser scanning microscopy (CLSM). To test the permeability of each formulation, sodium fluorescein was added to the mixture that was applied on excised pig skin. Even though the influence of Glyceryl monooleate (Gliseril monooleat) on the percutaneous absorption through hairless mouse skin has been studied, differences between the Glyceryl monooleate (Gliseril monooleat)/water formulations and how they affect permeability and distribution throughout the layers of the skin have not been investigated. This study might provide an insight to understand the effects of formulation on the skin permeation.2. Material and methods 2.1. Materials Glyceryl monooleate (Glyceryl monooleate (Gliseril monooleat)), propylene glycol, hexanediol, paraformaldehyde, sodium chloride, potassium chloride, potassium phosphate monobasic, potassium phosphate dibasic, and sodium fluorescein were purchased from Sigma–Aldrich Co. (St. Louis, MO, USA). Excised pig skin obtained from PWG Genetics Korea, Ltd. (Pyeongtaek, Gyeonggi, Korea). FSC 22 Frozen section media was purchased from Leica Biosystems (Wetzlar, Hesse, Germany). Hydrophobic PTFE membrane was purchased from Pall Corporation (New York, NY, USA). Hydrophilic nitrocellulose membrane was purchased from EMD Millipore (Billerica, MA, USA).2.2. Preparation of formulations Three different formulations were prepared for the current study (Table 1). Lyotropic liquid crystalline phases (cubic and lamellar phases) were produced by melting Glyceryl monooleate (Gliseril monooleat) in a vial at 45 °C and then propylene glycol and hexanediol were dissolved in the melted Glyceryl monooleate (Gliseril monooleat). Propylene glycol was utilized in order to slow down the drastic increase of viscosity during the cubic phase formation by mixing Glyceryl monooleate (Gliseril monooleat) and water. A small amount of hexanediol was added to prevent bacterial growth in the mixture and prolong the shelf-life. An aqueous solution of fluorescein was produced by dissolving hexanediol and sodium fluorescein in deionized water. The aqueous solution of sodium fluorescein was slowly added to the mixture while it was strongly agitated by an ultrasonic homogenizer to form lyotropic liquid crystalline phases.2.3. In vitro diffusion studies with membranes In vitro diffusion study was carried out using Franz-type diffusion cells assembled with hydrophobic PTFE membrane and hydrophilic nitrocellulose membrane between the donor and receptor chambers. The volume of each chamber was 12.5 ml and the diffusion area was 1.82 cm2. Pore size of the membranes was 0.45 μm. To simulate a skin's lipid-bilayer, hydrophobic membranes were dipped in melted Glyceryl monooleate (Gliseril monooleat) and soaked in receptor medium for 30 min before diffusion studies. After the membranes were soaked, the hydrophobic membrane was attached to the hydrophilic membrane and both remained attached during the diffusion experiment.The receptor chamber was filled with phosphate buffered saline (pH 7.4). The donor chamber containing the cubic phase, lamellar phase, or solution samples with 1 mg/ml of the sodium fluorescein were applied on the upper surface of the hydrophobic membrane. Receptor components were continuously stirred with a magnetic stirrer and samples were withdrawn at predetermined time intervals (1, 2, 3, 4, 6, 8, and 12 h). After withdrawing samples from the receptor, the receptor was replaced with the same volume of fresh phosphate buffered saline to maintain sink condition. The content of sodium fluorescein was analyzed by multi-mode microplate reader. The cumulative amount of sodium fluorescein released per surface area was obtained using the following equation:where Q is the cumulative amounts of sodium fluorescein released per surface area of the membrane (μg/cm2) and Cn is the concentration of the sodium fluorescein (μg/ml) determined at nth sampling interval. V is the volume of individual Franz-type diffusion cell, S is the volume of sampling aliquot (0.5 ml), and A is the surface area of membrane. The cumulative amounts released per surface area were plotted against time. The steady-state flux (J) was obtained from the slope of the linear portion of plotted cumulative released amounts of compound. The lag time (Tlag) was obtained from the intercept of extrapolated linear portion with time axis (x-axis). Statistical analysis was performed using the student's t test and analysis variance (one-way ANOVA, Dunnett's multiple comparison test of SigmaStat 3.5, Dundas software, Germany) with a P-value of ≤0.05 considered to be significant.2.4. Fluorescence assay Fluorescence emission spectra of sodium fluorescein were obtained using SpectraMax M3 multi-mode microplate reader (Molecular device, Sunnyvale, CA, USA). Excitation wavelength was 492 nm and emission wavelength was 515 nm with a 4 nm silt width. The spectra of samples were corrected by subtracting the corresponding buffer spectra. Before obtaining the fluorescence of diffused sodium fluorescein, linearity of the calibration curve was obtained by plotting the nominal concentration of the standard sodium fluorescein (x) versus the emission spectra intensity (y) in the tested concentration range. Accuracy and precision were determined by analyzing samples in triplicate six times on the same day.2.5. Confocal laser scanning microscopy (CLSM) Cubic, lamellar, and solution formulations containing 1 mg/ml of the fluorescein were applied onto the pig skin and left for 5 h and 24 h at 37 °C. After the treatment, skin samples were fixed with 4% paraformaldehyde for 24 h. The fixed skin samples were embedded in frozen section media and frozen overnight in a deep freezer at −82.7 °C. The frozen skin samples were cross-sectioned into slices 20 μm thick by Leica CM1520 cryostat for cell nuclei staining. Sections were stained with 1 μg/ml of 4′, 6-diamidino-2-phenylindole (DAPI) for 10 min at 37 °C. After washing with PBS, the cross-section of the skin samples were imaged by LSM 510 microscope (Carl Zeiss AG, Oberkochen, Baden-Württemberg, Germany) with dual excitation band of DAPI (358 nm) and FITC filter (488 nm). Fluorescence imaging processing was performed by ZEN 2012 software and Adobe Photoshop.3. Result and discussion 3.1. In vitro diffusion studies with membranes To validate the fluorescence assay method, calibration curves of the sodium fluorescein were plotted and found to be linear (R2 ≥ 0.999) in the tested range of 0.064–32 μg/ml (Table 2). The limit of detection (LOD) and limit of quantification (LOQ) were 0.015 and 0.046 μg/ml, respectively. The accuracy for 0.32, 1.6, and 32 mg/ml sodium fluorescein standard solutions (n = 3) was 2.25, 1.77, and 0.28, respectively (expressed as % variation of the mean). The precision for 0.32, 1.6, and 32 mg/ml sodium fluorescein standard solutions (n = 3) was 3.03, 2.32, and 0.19, respectively (expressed as % coefficient of variation).The diffusion profiles of sodium fluorescein in various formulations across the synthetic membrane are shown in Fig. 1. As the cumulative amount of sodium fluorescein released per unit surface area in the receptor phase was plotted against time, a linear relationships after a lag time was obtained. The diffusion coefficient and flux of each formulation were calculated from the slope and lag time (Table 3). Flux of sodium fluorescein across the synthetic membrane in descending order was the cubic phase (15.11 μg/cm2 h), lamellar phase (12.45 μg/cm2 h), and solution formulation (8.23 μg/cm2 h). The cumulative amount of sodium fluorescein released at 12 h and fluxes of the cubic and lamellar phases were significantly greater (P < 0.05) than those of the solution formulation. The cubic and lamellar phases released about 80 and 39 times more, respectively, compared to the solution. Since sodium fluorescein is hydrophilic and water-soluble, diffusion through an oil-wetted hydrophobic membrane may be a limiting factor. Differences in lag time and flux might cause significant differences in the amount of sodium fluorescein released between each Glyceryl monooleate (Gliseril monooleat)/water formulations. In addition, the hydrophobicity of Glyceryl monooleate (Gliseril monooleat) in each formulation may have an effect on the sodium fluorescein's permeability through oil-wetted hydrophobic membrane. In a study investigating the effect of permeation enhancers on transdermal delivery, Glyceryl monooleate (Gliseril monooleat) increased the flux across skin for both hydrophilic and hydrophobic drugs by inducing reversible disruption of the lamellar structure of the lipid bilayer and increasing the fluidity of lipids in skin.Even though the lamellar phase has more Glyceryl monooleate (Gliseril monooleat) than the cubic phase formulation, the cubic phase released a higher cumulative amount of sodium fluorescein. A reasonable explanation for this is that propylene glycol enhanced the release of sodium fluorescein in the cubic phase formulation by reducing its viscosity which increased membrane permeability. The lamellar phase shifted to the cubic phase as water content increasing during membrane permeation. The shift to cubic phase may have increased the viscosity and therefore decreased its mobility. It is likely that excess amounts of Glyceryl monooleate (Gliseril monooleat) might disturb diffusion through a membrane in lamellar phase. In the presence of propylene glycol, Glyceryl monooleate (Gliseril monooleat) also forms a liquid sponge phase which has a bicontinuous lipid water system. Previous research has demonstrated that the liquid sponge phase had a better diffusion profile than the cubic phase formulation. Even though cubic phase formulation might not form the liquid sponge phase during diffusion in these experiments, an interaction between Glyceryl monooleate (Gliseril monooleat) and propylene glycol could promote diffusion through the membranes. Hydration time might be a factor in the difference in the diffusion rates between the different formulations. A previous study found that samples hydrated prior to the experiments released large amounts of drug because hydrophilic channels were available during the release of the drug . As the initial water content increased, drug release increased due to the increased hydrophilic domain which accounted for the difference in the amount of drug initially released .3.2. Confocal microscopy imaging CLSM was used to observe the distribution of fluorescein in the skin layers after the application of cubic, lamellar, and solution formulation. Microscopic images of cross-sections perpendicular to the skin allowed us to observe the distribution pattern of the fluorescein in the deep region of the excised skin including the stratum corneum (SC), viable epidermis, and dermis. The diffusion profiles of sodium fluorescein into the skin was compared after the application of the different formulations. As shown in Fig. 2, the distribution of sodium fluorescein in the skin was visualized by CLSM after 5 h of topical application.Glyceryl monooleate (Gliseril monooleat) might facilitate the diffusion of sodium fluorescein through the viable epidermis and dermis. The cubic phase was uniformly distributed in the epidermis and dermis (Fig. 2A). The lamellar phase also showed relatively uniform distribution in epidermis and dermis with a small amount present in the SC (Fig. 2B). Most of the sodium fluorescein in the solution formulation was unable to permeate the SC region (Fig. 2C). The image of skin that had the solution formulation applied to it showed a relatively low intensity of fluorescence at the epidermis and dermal layer, but a very strong intensity on the SC. These results support the previous results of diffusion experiment using Franz-type diffusion cells that looked at flux, lag time, and diffusion coefficient between different formulations.Fig. 3 shows the confocal images of the skin after 24 h of sample application. The cubic and lamellar phase formulations showed much stronger fluorescence in the dermal layer compared to the solution formulation. Cubic and lamellar phases showed strong fluorescence in the dermis after 24 h of application compared to 5 h-images. Solution formulation also showed stronger fluorescence than its 5 h-image, but it was localized in the SC layer. This result might suggest that most of sodium fluorescein in the solution formulation might not be able to penetrate SC layer. However, with its low molecular weight sodium fluorescein might be distributed to the SC region which could not be removed during washing, and still showed localized fluorescence after 24 h (Fig. 3C).During a skin diffusion test, Glyceryl monooleate (Gliseril monooleat) might reversibly emulsify the lipid matrix of the skin and penetrate through the SC. Because adipose tissue and the hypodermis are more hydrophobic than other tissues they make up the skin, most Glyceryl monooleate (Gliseril monooleat) formulations might interact with the tissues and accumulate in them. Therefore, confocal images of samples treated with the cubic and lamellar phases showed stronger fluorescence at hypodermis and adipose tissues than other tissues in skin. In addition, the cubic and lamellar phases showed some localization of high intensity fluorescence in dermis and adipose tissues. The solution formulation showed no localization in the tissues. Differences in localization might be caused by the presence of Glyceryl monooleate (Gliseril monooleat) in formulation. Lipids such as oleic acid and Glyceryl monooleate (Gliseril monooleat) have a polar head and a relatively short hydrophobic carbon chain that increases membrane permeability by promoting disorder of intercellular lipids. In this study, intercellular lipid disorder might cause localization of the sodium fluorescein in the dermis and adipose tissue. Different absorption pathways might also cause difference in the amount of sodium fluorescein diffused between each formulation. Intercellular pathway seems to be predominant method of transdermal absorption when using the solution formulation, whereas the intercluster pathway is the most common method of absorption for the cubic and lamellar phase formulations. Higher Glyceryl monooleate (Gliseril monooleat) concentrations did not improve permeability. The intensity of the fluorescence in the dermis was directly correlated with an increased with the permeability and not Glyceryl monooleate (Gliseril monooleat) concentration. At 37 °C, Glyceryl monooleate (Gliseril monooleat) might exist in a cubic phase when the amount of water is greater than 40%. During the diffusion test, the lamellar phase might be hydrated by moisture in the skin and converted to cubic phase. Therefore, viscosity may increase, which decreases the mobility of the Glyceryl monooleate (Gliseril monooleat)/solvent mixture. 4. Conclusion This study suggests that Glyceryl monooleate (Gliseril monooleat) is feasible as an absorption enhancer for topical drugs. Franz-type diffusion test and CLSM images in excised pig skin showed improved permeability through the hydrophobic-hydrophilic membrane and excised pig skin. Both cubic and lamellar formulations with Glyceryl monooleate (Gliseril monooleat) showed higher permeability and diffusion profiles. By comparing the diffusion patterns and confocal images, the cubic phase performed significantly better than the lamellar formulation. The results suggest that differences of diffusion were caused by ability of the Glyceryl monooleate (Gliseril monooleat)/solvent mixture to induce lipid disorder in the skin samples. These results support the hypothesis that Glyceryl monooleate (Gliseril monooleat) induces intercellular lipid disorder. High Glyceryl monooleate (Gliseril monooleat)/water ratio does not correlate with high membrane permeability. The cubic phase contained lower Glyceryl monooleate (Gliseril monooleat) concentration compared to the lamellar phase but had better membrane permeability. Our study demonstrates that Glyceryl monooleate (Gliseril monooleat) is an important substance for SC permeation but the viscosity of this formulation needs to be further investigated to improve the diffusion efficacy of active ingredients.Glyceryl Monooleate is a clear or light yellow oil that is used as an antifoam in juice processing. It has been used as an emulsifier, a moisturizer, and a flavoring agent.Glycerol monooleate (C21H40O4) is a clear amber or pale yellow liquid. It is an oil soluble surfactant and is classified as a monoglyceride. It is used as an antifoam in juice processing and as a lipophilic emulsifier for water-in-oil applications. It is a moisturizer, emulsifier, and flavoring agent. Various forms of glycerol oleate are widely used in cosmetics and it is also used as an excipient in antibiotics and other drugs.Glyceryl Oleate occurs as off-white to yellow flakes or as a soft semisolid. It is dispersible in water and soluble in acetone, methanol, ethanol, cottonseed oil,and mineral Glyceryl Oleate is also known as Monoolein, Glyceryl Monooleate, and Glycerol Monooleate.Celecoxib (CXB) is a widely used anti-inflammatory drug that also acts as a chemopreventive agent against several types of cancer, including skin cancer. As the long-term oral administration of CXB has been associated with severe side effects, the skin delivery of this drug represents a promising alternative for the treatment of skin inflammatory conditions and/or chemoprevention of skin cancer. We prepared and characterized liquid crystalline systems based on glyceryl monooleate (Glyceryl monooleate (Gliseril monooleat)) and water containing penetration enhancers which were primarily designed to promote skin delivery of CXB. Analysis of their phase behavior revealed the formation of cubic and hexagonal phases depending on the systems' composition. The systems' structure and composition markedly affected the in vitro CXB release profile. Oleic acid reduced CXB release rate, but association oleic acid/propylene glycol increased the drug release rate. The developed systems significantly reduced inflammation in an aerosil-induced rat paw edema modl. The systems' composition and liquid crystalline structure influenced their anti-inflammatory potency. Cubic phase systems containing oleic acid/propylene glycol association reduced edema in a sustained manner, indicating that they modulate CXB release and/or permeation. Our findings demonstrate that the developed liquid crystalline systems are potential carriers for the skin delivery of CXB.TREATMENT OF HUMAN ERYTHROCYTE GHOST MEMBRANES WITH THE FUSOGENIC LIPID GLYCEROL MONOOLEATE INCREASED THE FLUIDITY OF THE MEMBRANE LIPIDS, BUT THE NONFUSOGENIC LIPID GLYCEROL MONOSTEARATE HAD NO EFFECT.IF ANY OF THESE ESTERS IS SIGNIFICANTLY TOXIC, THE ACID PORTION MUST BE HELD RESPONSIBLE, NOT THE GLYCEROL. /GLYCEROL ESTERS/Glyceryl monooleate (GMO) is one of the most popular amphiphilic lipids, which, in the presence of different amounts of water and a proper amount of stabilizer, can promote the development of well defined, thermodynamically stable nanostructures, called lyotropic liquid crystal dispersions. The aim of this study is based on the design, characterization, and evaluation of the cytotoxicity of lyotropic liquid crystal nanostructures containing a model anticancer drug such as doxorubicin hydrochloride. The drug is efficiently retained by the GMO nanosystems by a remote loading approach. The nanostructures prepared with different non-ionic surfactants (poloxamers and polysorbates) are characterized by different physico-chemical features as a function of several parameters, i.e., serum stability, temperature, and different pH values, as well as the amount of cryoprotectants used to obtain suitable freeze-dried systems. The nanostructures prepared with poloxamer 407 used as a stabilizer show an increased toxicity of the entrapped drug on breast cancer cell lines (MCF-7 and MDA-MB-231) due to their ability to sensitize multidrug-resistant (MDR) tumor cells through the inhibition of specific drug efflux transporters. Moreover, the interaction between the nanostructures and the cells occurs after just a few hours, evidencing a huge cellular uptake of the nanosystems.Glyceryl monooleate (GMO) is often described as a special lipid that plays an important role in drug delivery systems, due to its ability to self-assemble in water and to form a variety of well-defined, thermodynamically stable liquid crystal structures. It also exhibits long-range order in one, two, or three dimensions. GMO is widely known as a non-toxic, biodegradable and biocompatible product. It received generally recognized as safe (GRAS) status from the Food and Drug Administration (FDA) and is included in the Inactive Ingredients Guide.In the presence of a proper stabilizer , liquid crystal phases can be arranged in different supramolecular structures such as cubosomes or hexosomes, which could potentially beused for intravenous injection. This is because of their scarce viscosity as well as their ability to maintain the internal nanostructure of the bulk systems and keep it intact. Moreover, their stability in aqueous environments, their inexpensive raw materials as well as their well-defined structure and their higher membrane surface area allow them to retain significantly larger amounts of drugs then their lamellar counterparts such as liposomes. The excellent characteristics of these hosting matrices make these nanostructures excellent and promising carriers for various applications in the drug delivery field. The addition of surfactants can indeed influence the behavior of lipids in phases and are an important factor in preventing destabilizing phenomena of the colloidal dispersions in aqueous media, thus improving their shelf-life. Among the stabilizing agents, the most extensively employed for the preparation of the lyotropic liquid crystalline nanostructures are poly-oxy-ethylene(PEO)-based surfactants such as poloxamers and polysorbates. In particular, poloxamers are nonionic triblock copolymers composed of a central hydrophobic portion of polyoxypropylene oxide (PPO) linked to two hydrophilic blocks of poly-ethylene oxide (POE). Their peculiar characteristics depend on the lengths of the chains of the various units, and on the different molecular weights and physical forms. Indeed, they act as steric stabilizers by way of the adsorption of the hydrophobic units onto the surfaces of nanostructures, which prevents the fusion of particles and thus promotes the physical stability of a formulation.Moreover, polysorbates (PS) are nonionic, hydrophilic stabilizers made up of fatty acid esters of polyoxyethylene sorbitan. Their bone structure consists of a sorbitan ring with ethylene oxide polymers linked at three different hydroxyl positions. Their molecular weight is significantly lower, and they have shorter hydrophilic PEO chains, in addition to a hydrophobic anchor consisting of fatty acid. The current study was designed to compare GMO-nanostructures prepared with the most popular classes of non-ionic surfactants (polysorbates and poloxamers) as a function of temperature, serum stability at various pH values, and the cryoprotectants used to obtain suitable freeze-dried systems. The most promising formulations were chosen to encapsulate the hydrophilic anticancer drug, doxorubicin hydrochloride (DOX).

Glyceryl Monostearate Glyceryl monostearate is composed of primary and auxiliary emulsifiers for a wide variety of personal care formulas. It is supplied as cream flakes. Glyceryl monostearate is an emulsifier for a wide variety of personal care applications. Product: Cerasynt Stearates Industries: Personal Care Form: White to off-white flakes Use level: 0.25 - 3.0% Features & Benefits Nonionic auxiliary emulsifier Emulsion stabilizer Biodegradable 100% Natural Vegan suitable Impurities and other Glyceryl monostearate risks According to a report in the International Journal of Toxicology by the cosmetic industry’s own Cosmetic Ingredient Review (CIR) committee, impurities found in various PEG compounds include ethylene oxide; 1,4-dioxane; polycyclic aromatic compounds; and heavy metals such as lead, iron, cobalt, nickel, cadmium, and arsenic. Many of these impurities are linked to cancer. PEG compounds often contain small amounts of ethylene oxide. Ethylene oxide (found in PEG-4, PEG-7, PEG4-dilaurate, and PEG 100) is highly toxic — even in small doses — and was used in World War I nerve gas. Exposure to ethylene glycol during its production, processing and clinical use has been linked to increased incidents of leukemia as well as several types of cancer. Finally, there is 1,4-dioxane (found in PEG-6, PEG-8, PEG-32, PEG-75, PEG-150, PEG-14M, and PEG-20M), which, on top of being a known carcinogen, may also combine with atmospheric oxygen to form explosive peroxides — not exactly something you want going on your skin. Even though responsible manufacturers do make efforts to remove these impurities (1,4-dioxane that can be removed from cosmetics through vacuum stripping during processing without an unreasonable increase in raw material cost), the cosmetic and personal care product industry has shown little interest in doing so. Surprisingly, PEG compounds are also used by natural cosmetics companies. If you find Glyceryl monostearate in your cosmetics… Although you might find conflicting information online regarding Polyethylene Glycol, PEGs family and their chemical relatives, it is something to pay attention to when choosing cosmetic and personal care products. If you have sensitive or damaged skin it might be a good idea to avoid products containing PEGs. Using CosmEthics app you can easy add PEGs to personal alerts. In our last blog post we wrote about vegan ingredients. Natural glycols are a good alternative to PEGs, for example natural vegetable glycerin can be used as both moisturiser and emulsifier. CosmEthics vegan list can help you find products that use vegetable glycerin as wetting agent. At present, there is not enough information shown on product labels to enable you to determine whether PEG compounds are contaminated. But if you must buy a product containing PEGs just make sure that your PEGs are coming from a respected brand. Glyceryl stearate and Glyceryl monostearate is a combination of two emulsifying ingredients. The stabilising effect of both means that the product remains blended and will not separate. Description Glyceryl stearate is a solid and waxy compound. It is made by reacting glycerine (a soap by-product) with stearic acid (a naturally occurring, vegetable fatty acid). Glyceryl monostearate is an off-white, solid ester of polyethylene glycol (a binder and a softener) and stearic acid. Applications Ideal for styling creams/lotions, conditioners, body care, facial care, sun care Related Applications Personal Care Cosmetics Hair Care Skin Care Sun Care Related Benefits Personal Care Natural Vegan Suitable Related Functions Personal Care Emulsifiers Glyceryl Stearate. Glyceryl monostearate ester acts as an emulsion stabilizer and non-ionic auxiliary emulsifier. Glyceryl monostearate ester is suggested for use in creams and lotions, conditioners and styling creams/lotions, body care, face and body washes, facial care, after-sun, self-tanning, and sunscreen applications. The Cerasynt esters range provides a variety of emulsifiers to meet formulation requirements. PROPERTIES Auxiliary emulsifiers. APPLICATIONS A wide variety of personal care formulas. Glyceryl monostearate is a premium quality nonionic stabilizer and emulsifier. Manufactured using the highest quality raw materials for batch-to-batch reproducibility. What Is Glyceryl monostearate? Glyceryl monostearate and Glyceryl monostearate SE are esterification products of glycerin and stearic acid. Glyceryl monostearate is a white or cream-colored wax-like solid. Glyceryl monostearate is a "Self-Emulsifying" form of Glyceryl monostearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glyceryl monostearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is Glyceryl monostearate used in cosmetics and personal care products? Glyceryl monostearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glyceryl monostearate, and Glyceryl monostearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Scientific Facts: Glyceryl monostearate is made by reacting glycerin with stearic acid, a fatty acid obtained from animal and vegetable fats and oils. Glyceryl monostearate SE is produced by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide yielding a product that contains Glyceryl monostearate as well as potassium stearate and/or sodium stearate. What Is Glyceryl monostearate Glyceryl monostearate is esterification products of glycerin and stearic acid. Glyceryl monostearate is a white or cream-colored wax-like solid. Glyceryl monostearate SE is a "Self-Emulsifying" form of Glyceryl monostearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glyceryl monostearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is it used in cosmetics and personal care products? Glyceryl monostearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glyceryl monostearate, and Glyceryl monostearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Glyceryl monostearate is derived from palm kernel, vegetable or soy oil and is also found naturally in the human body. It acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It easily penetrates the skin and slows the loss of water from the skin by forming a barrier on the skin's surface. It has been shown to protect skin from free-radical damage as well. Functions of Glyceryl monostearate Glyceryl monostearate is derived from palm kernel, vegetable or soy oil and is also found naturally in the human body. It acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance (Source). It easily penetrates the skin and slows the loss of water from the skin by forming a barrier on the skin's surface. It has been shown to protect skin from free-radical damage as well. Chemically, Glyceryl monostearate is used to stabilize products, decrease water evaporation, make products freeze-resistant, and keep them from forming surface crusts. Description: Glyceryl monostearate SE (self-emulsifying as it contains a small amount 3-6% of potassium stearate) is the monoester of glycerin and stearic acid. Vegetable origin. It is an emulsifier with a HLB value of 5.8 and thus useful for making water-in-oil emulsions. It can also be used as a co-emulsifier and thickener for oil- in-water formulations. Off-white flakes, bland odor. Soluble in oil. CAS: 123-94-4 INCI Name: Glyceryl monostearate Properties: Emulsifies water and oil phase, acts as stabilizer and thickener in o/w formulations, widely used in a variety of different cosmetic formulations. Use: Add to oil/emulsifier phase of formulas, melts at 55°C/130°F. Use level: 1-10%. For external use only. Applications: Moisturizing creams, lotions, ointments, antiperspirant, hair care and sunscreen. Glyceryl monostearate (GMS) is one of the most commonly used ingredients in personal care formulations. But it's a material that is not well understood by most formulators. GMS (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. Glyceryl monostearate, also known as Glyceryl MonoStearate, or GMS, is EcoCert certified. Glyceryl monostearate is the natural glyceryl ester from stearic acid (glycerin and stearic acid) which offers skin conditioning, moisturization and hydration due to the glycerin component. Functions as a non-ionic opacifier, thickener, and formulation stabilizer, where it also imparts a softer, smoother, feel to your emulsions. Glyceryl monostearate is one of the best choices, for thickening and stabilizing, to use in combination with the lactylates, where it also functions as an emollient, and gives the emulsion more smoothness. Glyceryl monostearate is the end result of reaction between glycerin and stearic acid. We all know what glycerin is and does (generally vegetable based humectant), and stearic acid is a fatty acid compound extracted from a variety of vegetable, animal, and oil sources such as palm kernel and soy. The end result of the reaction with glycerin and stearic acid is a cream-colored, waxy like substance. Details A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth. Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable. NAMELY Glycerol stearate is used as a non-ionic emulsifier or emollient in cosmetic products. It is widely used in moisturizers and is also found in hair care products for its antistatic properties. It can be derived from palm, olive or rapeseed oil... It is authorized in bio. Its functions (INCI) Emollient : Softens and softens the skin Emulsifying : Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil) This ingredient is present in 11.81% of cosmetics. Hand cream (46.51%) Moisturizing cream box (46.15%) Anti-aging night face cream (45.88%) Anti-aging hand cream (43.75%) Mascara (42.73%) Glyceryl monostearate Glyceryl monostearate is the natural glyceryl ester of glycerin and stearic acid. It offers excellent hydration and moisturization. It acts as a non-ionic opacifier, thickener, emollient and formulation stabilizer. It is used in skin care and body care applications. Glyceryl monostearate is classified as : Emollient Emulsifying CAS Number 31566-31-1 EINECS/ELINCS No: 250-705-4 COSING REF No: 34103 INN Name: glyceryl monostearate PHARMACEUTICAL EUROPEAN NAME: glyceroli monostearas Chem/IUPAC Name: Glyceryl MonoStearate Glyceryl monostearate Learn all about Glyceryl monostearate, including how it's made, and why Puracy uses Glyceryl monostearate in our products. Derived from: coconut Pronunciation: (\ˈglis-rəl\ \stē-ə-ˌrāt\) Type: Naturally-derived Other names: monostearate What Is Glyceryl monostearate? Glyceryl monostearate, also called glyceryl monostearate, is a white or pale yellow waxy substance derived from palm kernel, olives, or coconuts. What Does Glyceryl monostearate Do in Our products? Glyceryl monostearate is an emollient that keeps products blended together; it can also be a surfactant, emulsifier, and thickener in food — often it’s used as a dough conditioner and to keep things from going stale.[1] In our products, however, Glyceryl monostearate is used for its most common purpose — to bind moisture to the skin. For this reason, it is a common ingredient in thousands of cosmetic products, including lotions, makeup, skin cleansers, and other items. Why Puracy Uses Glyceryl monostearate We use Glyceryl monostearate in several of our products as a moisturizer; it also forms a barrier on the skin and prevents products from feeling greasy. As an emulsifier, it also allows products to stay blended.[5] Several studies and clinical tests find that Glyceryl monostearate causes little or no skin or eye irritation and is not a danger in formulations that might be inhaled.[6,7,8] In addition, a number of clinical trials have found that Glyceryl monostearate in moisturizers can lessen symptoms and signs of atopic dermatitis, including pruritus, erythema, fissuring, and lichenification.[9] In 1982 and again in 2015, the Cosmetic Ingredient Review deemed the ingredient safe for use in cosmetics.[10] Whole Foods has deemed the ingredient acceptable in its body care quality standards.[11] How Glyceryl monostearate Is Made Glyceryl monostearate is formed through a reaction of glycerin with stearic acid, which is a fatty acid that comes from animal and vegetable fats and oils. Glyceryl monostearate SE, the self-emulsifying form of the substance, is made by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide. That produces a substance that contains Glyceryl monostearate, potassium stearate, and/or sodium stearate Glyceryl monostearate (GMS) is one of the most commonly used ingredients in personal care formulations. But it’s a material that is not well understood by most formulators. GMS (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. LGN-based emulsions containing thickening polymers are the most common type of oil-in-water formulations sold globally. Most GMS used in personal care products should actually be called glyceryl distearate (EU), since many common grades only contain around 40% alpha monostearate (EU), 5% glyceryl tristearate (EU), and 50% glyceryl distearate. There are also grades commercially available that contain 30%, 60%, and 90% GMS. The 90% alpha mono grades can only be produced by molecular distillation and are widely used in the food industry. Functionally, there is a big difference in performance if you use a 90% versus 40% mono. A 90% mono has a higher melting point (69°C versus 58-63°C), lighter skin feel, and a higher HLB (EU) (~4-5, versus ~3). The higher HLB of the 90% mono enables you to form LGNs much easier with lower emulsifier levels and energy than when using cetyl (EU)/stearyl alcohol (EU). There are also self-emulsifying (SE) grades of GMS available, which are typically combined with PEG 100 stearate (EU), potassium stearate (EU), or sodium lauryl sulfate (EU). Glyceryl monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.[3] It takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic. Chemically it is the glycerol ester of stearic acid. Structure, synthesis, and occurrence Glyceryl monostearate exists as three stereoisomers, the enantiomeric pair of 1-Glyceryl monostearate and 2-Glyceryl monostearate. Typically these are encountered as a mixture as many of their properties are similar. Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol. Glyceryl monostearate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase. It is present at very low levels in certain seed oils. Uses Glyceryl monostearate is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant. It is also used in cosmetics and hair-care products.[5] Glyceryl monostearate is largely used in baking preparations to add "body" to the food. It is somewhat responsible for giving ice cream and whipped cream their smooth texture. It is sometimes used as an antistaling agent in bread. What Is It? Glyceryl monostearate and Glyceryl Stearate SE are esterification products of glycerin and stearic acid. Glyceryl monostearate is a white or cream-colored wax-like solid. Glyceryl monostearate SE is a "Self-Emulsifying" form of Glyceryl monostearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glyceryl monostearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is it used in cosmetics and personal care products? Glyceryl monostearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glyceryl monostearate, and Glyceryl monostearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Scientific Facts: Glyceryl monostearate is made by reacting glycerin with stearic acid, a fatty acid obtained from animal and vegetable fats and oils. Glyceryl Stearate SE is produced by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide yielding a product that contains Glyceryl monostearate as well as potassium stearate and/or sodium stearate. Glyceryl monostearate is the natural glyceryl ester of glycerin and stearic acid. It offers excellent hydration and moisturization. It acts as a non-ionic opacifier, thickener, emollient and formulation stabilizer. It is used in skin care and body care applications. Glyceryl monostearate is classified as : Emollient Emulsifying Learn all about Glyceryl monostearate, including how it's made, and why Puracy uses Glyceryl monostearate in our products. Derived from: coconut Pronunciation: (\ˈglis-rəl\ \stē-ə-ˌrāt\) Type: Naturally-derived Other names: monostearate What Is Glyceryl monostearate? Glyceryl monostearate, also called glyceryl monostearate, is a white or pale yellow waxy substance derived from palm kernel, olives, or coconuts. What Does Glyceryl monostearate Do in Our products? Glyceryl monostearate is an emollient that keeps products blended together; it can also be a surfactant, emulsifier, and thickener in food — often it’s used as a dough conditioner and to keep things from going stale.[1] In our products, however, Glyceryl monostearate is used for its most common purpose — to bind moisture to the skin. For this reason, it is a common ingredient in thousands of cosmetic products, including lotions, makeup, skin cleansers, and other items.[2,3] Why Puracy Uses Glyceryl monostearate We use Glyceryl monostearate in several of our products as a moisturizer; it also forms a barrier on the skin and prevents products from feeling greasy. As an emulsifier, it also allows products to stay blended.[5] Several studies and clinical tests find that Glyceryl monostearate causes little or no skin or eye irritation and is not a danger in formulations that might be inhaled.[6,7,8] In addition, a number of clinical trials have found that Glyceryl monostearate in moisturizers can lessen symptoms and signs of atopic dermatitis, including pruritus, erythema, fissuring, and lichenification.[9] In 1982 and again in 2015, the Cosmetic Ingredient Review deemed the ingredient safe for use in cosmetics.[10] Whole Foods has deemed the ingredient acceptable in its body care quality standards.[11] How Glyceryl monostearate Is Made Glyceryl monostearate is formed through a reaction of glycerin with stearic acid, which is a fatty acid that comes from animal and vegetable fats and oils. Glyceryl monostearate SE, the self-emulsifying form of the substance, is made by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide. That produces a substance that contains Glyceryl monostearate, potassium stearate, and/or sodium stearate. Glyceryl stearate (Glyceryl monostearate) is one of the most commonly used ingredients in personal care formulations. But it’s a material that is not well understood by most formulators. Glyceryl monostearate (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. LGN-based emulsions containing thickening polymers are the most common type of oil-in-water formulations sold globally. Most Glyceryl monostearate used in personal care products should actually be called glyceryl distearate (EU), since many common grades only contain around 40% alpha monostearate (EU), 5% glyceryl tristearate (EU), and 50% glyceryl distearate. There are also grades commercially available that contain 30%, 60%, and 90% Glyceryl monostearate. The 90% alpha mono grades can only be produced by molecular distillation and are widely used in the food industry. Functionally, there is a big difference in performance if you use a 90% versus 40% mono. A 90% mono has a higher melting point (69°C versus 58-63°C), lighter skin feel, and a higher HLB (EU) (~4-5, versus ~3). The higher HLB of the 90% mono enables you to form LGNs much easier with lower emulsifier levels and energy than when using cetyl (EU)/stearyl alcohol (EU). There are also self-emulsifying (SE) grades of Glyceryl monostearate available, which are typically combined with PEG 100 stearate (EU), potassium stearate (EU), or sodium lauryl sulfate (EU). Glyceryl monostearate Glyceryl monostearate is created by the esterification of glycerin and stearic acid. Glyceryl monostearate creates an excellent emulsion and when used in combination with other emulsifiers, creates a stable lotion. Characteristics An interesting characteristic of Glyceryl monostearate is the ability to make the oils which are combined in the emulsion non greasy, so for example Sunflower can be combined, without adding greasiness to the final product, allowing creams and lotions to be produced which carry the properties of the oil without the greasiness. Glyceryl monostearate can be used to pearlise shower gel, shampoo and hand wash if added in combination with glycerine. How to use Heat the Glyceryl monostearate to 60c - 70c within the oil stage of your formulations. Ensure the Glyceryl monostearate is fully dissolved into your oil stage (use agitation if required) in order to minimise the risk of graininess in your final formulation. Precautions At pure usage levels it can cause irritation to the skin. When blending always take the following precautions: Use gloves (disposable are ideal) Take care when handling hot oils Wear eye protection Work in a well ventilated room Keep ingredients and hot oils away from children If ingested, seek immediate medical advice If contact made with eyes, rinse immediately with clean warm water and seek medical advice if in any doubt. Safety First In addition to our precautions and general safety information, we always recommend keeping a first aid kit nearby. You are working with hot water and oils, accidents can happen, so always be prepared! Is Glyceryl monostearate Safe? Toxicity The safety of PEG compounds has been called into question in recent years. The questioning of the safety of this ingredient is due to toxicity concerns that result from impurities found in PEG compounds. The impurities of concern are ethylene oxide and 1,4 dioxane, both are by-products of the manufacturing process. Both 1,4 dioxane and ethylene oxide have been suggested to be linked with breast and uterine cancers. While these impurities may have been a concern previously, ingredient manufacturers and improved processes have eliminated the risk of impurities in the final product. The level of impurities that were found initially in PEG manufacturing was low in comparison to the levels proposed to be linked to cancers. Longitudinal studies or studies over a long period of use of PEG compounds have not found any significant toxicity or any significant impact on reproductive health. When applied topically, Glyceryl monostearate is not believed to pose significant dangers to human health. It doesn’t penetrate deeply into the skin and isn’t thought to have bioaccumulation concerns when used topically. Irritation Through research, PEG compounds have exhibited evidence that they are non-irritating ingredients to the eyes or the skin. This research used highly concentrated forms of the ingredient, concentrations that would not be found in your skincare products. The Cosmetic Ingredient Review Expert Panel found PEG compounds to be non-photosensitizing and non-irritating at concentrations up to 100%. However, despite the evidence suggesting that PEG compounds are non-irritating, some research has indicated that irritation can occur when the skin is broken or already irritated. In a study that was trialing the use of PEG containing antimicrobial cream on burn patients, some patients experienced kidney toxicity. The concentration of PEG compounds was identified to be the culprit. Given that there was no evidence of toxicity in any study of PEGs and intact skin, the Cosmetic Ingredient Review Expert Panel amended their safety guidelines to exclude the use of PEG containing products on broken or damaged skin. Is Glyceryl monostearate Vegan? Depending on the source of the stearic acid used to make Glyceryl monostearate, it may be vegan. Most of the time, stearic acid is derived from plants. However, it can also be derived from animal origin. If it is of animal origin, the product has to comply with animal by-product regulation. Check with the brand you are thinking of using to determine whether their Glyceryl monostearate is derived from a plant or animal source. Why Is Glyceryl monostearate Used? Emulsifier Glyceryl monostearate is included in skincare and beauty products for a variety of reasons, ranging from making the skin softer to helping product formulations better keep their original consistency. As an emollient, Glyceryl monostearate is included within skincare product formulations to give the skin a softer feel. It achieves this through strengthening the skin’s moisture barrier by forming a thin fatty layer on the skin’s surface, which prevents moisture loss and increases overall hydration. This moisturizing effect increases the hydration of skin cells, which in turn makes the skin softer and boosts skin health. Texture Another use for Glyceryl monostearate has to do with its emulsification properties. Emulsifiers are valued in the skincare and personal care industries because of their ability to mix water and oils. Without this ability, the oils in many formulations would begin to separate from the water molecules, thus undermining product texture and consistency. Glyceryl monostearate is also used to help to cleanse through mixing oil and dirt so that it can be rinsed away. Surfactant Lastly, Glyceryl monostearate can also act as a surfactant, when used in body and facial cleansers. Surfactants disrupt surface tension, helping to mix water and oil. This characteristic helps the ingredient cleanse the skin by mixing oil with water, lifting dirt trapped inside the skin’s oils, and rinsing it away from the skin. What Types of Products Contain Glyceryl monostearate? There are many products in the skin and personal care industry that are formulated with Glyceryl monostearate because of its benefits to formulations and its relative safety. Facial cleansers, shampoos, lotions, and face creams have all been known to contain this ingredient. If you’ve had problems with this ingredient before, or if your doctor has advised you to stay away from Glyceryl monostearate, it’s vital to read ingredient labels for any personal care product as it has many applications. What are PEGs? You have probably noticed that many of cosmetics and personal care products you use have different types of PEGs among ingredients. PEG, which is the abbreviation of polyethylene glycol, is not a definitive chemical entity in itself, but rather a mixture of compounds, of polymers that have been bonded together. Polyethylene is the most common form of plastic, and when combined with glycol, it becomes a thick and sticky liquid. PEGs are almost often followed by a number, for example PEG-6, PEG-8, PEG 100 and so on. This number represents the approximate molecular weight of that compound. Typically, cosmetics use PEGs with smaller molecular weights. The lower the molecular weight, the easier it is for the compound to penetrate the skin. Often, PEGs are connected to another molecule. You might see, for example, Glyceryl monostearate as an ingredient. This means that the polyethylene glycol polymer with an approximate molecular weight of 100 is attached chemically to stearic acid. In cosmetics, PEGs function in three ways: as emollients (which help soften and lubricate the skin), as emulsifiers (which help water-based and oil-based ingredients mix properly), and as vehicles that help deliver other ingredients deeper into the skin. What effect do Glyceryl monostearate have on your skin? Polyethylene glycol compounds have not received a lot of attention from consumer groups but they should. The most important thing to know about PEGs is that they have a penetration enhancing effect, the magnitude of which is dependent upon a variety of variables. These include: both the structure and molecular weight of the PEG, other chemical constituents in the formula, and, most importantly, the overall health of the skin. PEGs of all sizes may penetrate through injured skin with compromised barrier function. So it is very important to avoid products with PEGs if your skin is not in best condition. Skin penetration enhancing effects have been shown with PEG-2 and PEG-9 stearate. This penetration enhancing effect is important for three reasons: 1) If your skin care product contains a bunch of other undesirable ingredients, PEGs will make it easier for them to get down deep into your skin. 2) By altering the surface tension of the skin, PEGs may upset the natural moisture balance. 3) Glyceryl monostearate are not always pure, but often come contaminated with a host of toxic impurities.

Glyceryl monostearate exists in the form of a white or cream, hard, waxy mass or greasy powder, flakes or beads.
Glyceryl monostearate, also known as monostearin, is a mixture of variable proportions of glyceryl monostearate (C21H42O4), and glyceryl esters of fatty acids present in commercial stearic acid.
Glyceryl monostearate is prepared by glycerolysis of certain fats or oils that are derived from edible sources or by esterification, with glycerin, of stearic acid that is derived from edible sources.

CAS Number: 31566-31-1
Molecular Formula: C21H42O4
Molecular Weight: 358.56
EINECS No: 250-705-4

Glyceryl Monostearate (GMS) is a mixture of monoacylgcerols, mostly monosteroylglycerol, together with quantities of di-and triacylglycerols.
Glyceryl Monostearate (commonly abbreviated as GMS) is a lipoid material made up of a mixture of various proportions of monoacylgcerols, mostly monosteroylglycerol, together with quantities of di-and triacylglycerol.
Although the names glyceryl monostearate and mono-and di-glycerides are used for several esters of long-chain fatty acids.

Glyceryl monostearate is waxy to the touch and has a slight, mild fatty odor and taste The USP describes glyceryl monostearate as consisting of not less than 90% of monoglycerides, chiefy glyceryl monostearate and glyceryl monopalmitate.
Glycerol monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.
Glyceryl monostearate takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.

Glyceryl monostearate is the glycerol ester of stearic acid.
Glyceryl monostearate is also used as hydration powder in exercise formulas.
Glyceryl Monostearate, also known as GMS or glycerol monostearate, is an organic compound commonly used as an emulsifier in various industries, including food, cosmetics, and pharmaceuticals.

Glyceryl monostearate is a glycerol ester of stearic acid, which means it is composed of glycerol and stearic acid molecules.
Glyceryl Monostearate is usually found in the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic, meaning it absorbs moisture from the surrounding environment.
Glyceryl monostearate is insoluble in water but soluble in organic solvents like ether, benzene, and ethanol.

While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades:
40–55 percent monoglycerides The PhEur 6.0 describes glyceryl monostearate 40–55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols.
Glyceryl monostearate contains 40–55% of monoacylglycerols, 30–45% of diacylglycerols, and 5–15% of triacylglycerols.
This PhEur grade corresponds to mono- and di-glycerides USP– NF, which has similar specifications (not less than 40% monoglycerides).

90 percent monoglycerides The USP32–NF27 describes glyceryl monostearate as consisting of not less than 90% of monoglycerides of saturated fatty acids, chiefly glyceryl monostearate (C21H42O4) and glyceryl monopalmitate (C19H38O4).
The commercial products are mixtures of variable proportions of glyceryl monostearate and glyceryl monopalmitate.
Glyceryl monostearate is a white to cream-colored, wax-like solid in the form of beads, flakes, or powder.

Glyceryl monostearate is waxy to the touch and has a slight fatty odor and taste.
Glyceryl monostearate is a glycerol ester made from soybean oil derived fatty acid.
Glyceryl monostearate finds uses in both food and cosmetic applications.

Glycerol monostearate exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.
Typically these are encountered as a mixture as many of their properties are similar.
Glycerol monostearate, commonly known as GMS, is an organic molecule used as an emulsifier.

Glyceryl monostearate is a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Glyceryl monostearate is a glycerol ester of stearic acid. It occurs naturally in the body as a by-product of the breakdown of fats, and is also found in fatty foods.
Glyceryl monostearate is a food additive used as a thickening, emulsifying, anti-caking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant. It is also used in cosmetics and hair care products.

Glyceryl monostearate, C21H42O4, also known as monostearin, is a mixture of variable proportions of glyceryl monostearate, glyceryl monopalmitate , and glyceryl esters of fatty acids present in commercial stearic acid.
Glyceryl monostearate can be used as an emulsifier.
Glyceryl monostearate also occurs naturally in the body as a fat metabolite, and is present in foods with high fat content.

Glyceryl monostearate is used as a protective coating for hygroscopic powders, and a solidifier and control release agent.
Organic Certified Glyceryl Monostearate, referred to as GMS for short, is a solid, waxy substance carrying a white appearance and minimal to no odor.
Glyceryl monostearate is produced by distilling cold-pressed organic flax seed oil or sunflower oil to yield two parts, organic glycerin and organic fatty acids.

The fatty acid byproduct portion are fractionated to produce saturated fatty acids which will react with the organic glycerin to form Organic Glyceryl Monostearate.
Glyceryl monostearate, is most sought after for its emulsifying properties, the ability to bind water and oil together in a formulation which would naturally separate. Emulsifiers are an integral part of product development and formulation, used throughout cosmetic and personal-care manufacturing to food and beverage engineering, along with a wide range of industrial applications.

Glyceryl monostearate is a common food additive to thicken the consistency of a combination of ingredients, prevent caking, or act as an added preservative.
Glyceryl monostearates natural emollient characteristics make it suitable for a multitude of topical skincare products.

Melting point: 78-81 °C
Boiling point: 410.96°C (rough estimate)
Density: 0.9700
refractive index: 1.4400 (estimate)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Soluble in hot ethanol, ether, chloroform, hot acetone, mineral oil, and fixed oils. Practically insoluble in water, but may be dispersed in water with the aid of a small amount of soap or other surfactant.
form: Powder
color: Pure-white or cream-colored, wax-like solid
Odor: faint odor
Water Solubility: Soluble in hot organic solvents.Soluble in hot water. Slightly soluble in ethanol. Insoluble in aliphatic solvents.

The self-emulsifying grades of glyceryl monostearate are incompatible with acidic substances.
Glycerol monostearate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.
Glyceryl monostearate is present at very low levels in certain seed oils.

Glyceryl monostearate is a self emulsifying wax.
Glyceryl monostearate is located in dozens of personal care products, including moisturizers, eye cream, sunscreen, makeup and hand creams.
Direct Chems provide Glyceryl monostearate SE which is self emulsifying in pearl form and can be used as a viscosity enhancer adding emollient properties which makes skin softer and supple.

One of the primary functions of Glyceryl Monostearate is its role as an emulsifying agent.
Glyceryl monostearate helps to stabilize and blend two or more immiscible substances, such as oil and water, in a uniform mixture.
This property is particularly useful in the food industry for creating smooth and stable emulsions, such as salad dressings, mayonnaise, and sauces.

Glyceryl Monostearate can modify the texture of various food products.
In ice cream, for example, Glyceryl monostearate helps prevent the formation of ice crystals and improves the smoothness and creaminess of the final product.
Glyceryl monostearate also aids in the stabilization of whipped toppings and enhances the mouthfeel of certain foods.

Glyceryl monostearate, also known as glyceryl stearate, is an organic compound that belongs to the class of esters known as fatty acid glycerides.
Glyceryl monostearate is derived from stearic acid, a saturated fatty acid, and glycerol, a trihydroxy alcohol.

Glyceryl monostearate is commonly used in the food and cosmetic industries as an emulsifier, stabilizer, and thickening agent.
In food products, it helps to blend ingredients that would otherwise separate, such as oil and water.
Glyceryl monostearate can be found in various food items like ice cream, baked goods, margarine, and sauces.

In the cosmetic industry, glyceryl monostearate is used in creams, lotions, and other skincare products as an emulsifier to combine oil and water-based ingredients, thus ensuring a smooth texture and preventing separation.
Glyceryl monostearate also acts as a thickener, improving the consistency and stability of the products.

Glyceryl monostearate is generally considered safe for consumption and topical use, although some individuals may be sensitive or allergic to it.
As with any ingredient, Glyceryl monostearate is important to follow proper dosage and usage guidelines provided by manufacturers.
If you have specific concerns or questions about its use, it's best to consult with a healthcare professional or contact the relevant regulatory authorities for more information.

Glyceryl Monostearate prevents powders and granular substances from clumping or sticking together.
By reducing moisture absorption and maintaining the flowability of powdered ingredients, it helps extend the shelf life of food products.
Glyceryl Monostearate can act as a release agent.

Glyceryl monostearate is used in the manufacturing of tablets and capsules to facilitate the controlled release of active ingredients, ensuring proper absorption and therapeutic effects.
Glyceryl Monostearate is widely used in cosmetic and personal care products.
Glyceryl monostearate can function as an emollient, providing moisturizing properties to lotions, creams, and ointments.

Glyceryl monostearate helps stabilize oil-in-water emulsions and contributes to the overall stability and texture of cosmetic formulations.
Glyceryl monostearate has a chemical formula C21H42O4.
Glyceryl monostearate consists of a glycerol molecule esterified with a single stearic acid molecule.

Glyceryl monostearate has hydrophilic (water-loving) and lipophilic (fat-loving) properties, which make it an effective emulsifier.
It can form stable emulsions by reducing the surface tension between water and oil phases, allowing them to mix uniformly.
In addition to its emulsifying properties, glyceryl monostearate acts as a stabilizer, preventing the separation of ingredients in food and cosmetic formulations.

Glyceryl monostearate also contributes to the texture and mouthfeel of products, providing a smooth and creamy consistency.
Glyceryl monostearate can be derived from both animal and plant sources.
Animal-based sources typically involve the reaction of stearic acid with animal fats, while plant-based sources involve the reaction with vegetable oils, such as palm oil or soybean oil.

Glyceryl monostearate is considered safe for use in food and cosmetics by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).
Glyceryl monostearate has been assigned the "Generally Recognized as Safe" (GRAS) status in the United States.

Other applications: Apart from its use in food and cosmetics, glyceryl monostearate is also utilized in pharmaceuticals as a binder, solubilizer, and lubricant in tablet and capsule formulations.
Glyceryl Monostearate is generally recognized as safe (GRAS) by regulatory authorities when used in accordance with approved levels.
However, individuals with specific allergies or sensitivities may experience adverse reactions, so it's always recommended to check product labels and consult with healthcare professionals if necessary.

When applied topically, its Glycerol constituent makes Glyceryl monostearate SE a fast-penetrating emollient that helps to create a protective barrier on the surface of the skin.
Glyceryl monostearate helps retain hydration and slow the loss of moisture.
This reduced rate of water evaporation helps to lubricate, condition, soften, and smoothe the skin.

Glyceryl monostearates protective properties extend to its antioxidant qualities, which help protect the skin against damage caused by free radicals.
Glyceryl monostearate is produced industrially by reacting triglycerides with glycerol.
Glyceryl monostearate occurs naturally in the body as a byproduct of fat breakdown and is found in low levels in certain seed oils.

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid .
Glyceryl monostearate is commonly used as an emulsifier in foods.
When added to natural formulations, Glyceryl monostearate have stabilizing effects on the final product, which means it helps the other ingredients in the formulation to continue functioning effectively in order to go on exhibiting their beneficial properties.

Glyceryl monostearate helps to balance the product’s pH value and thereby prevents the product from becoming overly acidic or alkaline.
Glyceryl monostearate helps increase shelf life, prevents products from freezing or from developing crusts on their surfaces, and it helps lessen the greasy nature of some oils that may be added to cosmetics formulations.

In formulations that are oil-based, the thickening properties of Glyceryl monostearate help to scale down the need for co-emulsifiers and, in emulsions with big water phases, Glyceryl monostearate can help develop liquid crystal phases as well as crystalline gel phases.
As an opacifier, it makes transparent or translucent preparations opaque, thus protecting them from or increasing their resistance to being penetrated by visible light.

Glyceryl monostearate also helps to boost or balance the appearance of pigments and to improve the density of the final product for a luxuriously smooth and creamy texture.
Glyceryl monostearate also acts as a fast penetrating emollient which helps retain hydration, lubricate, condition and soften skin.
They slow loss of moisture so is ideal when adding to natural formulations.

Glyceryl monostearate enables other ingredients in the formulation to continue functioning effectively in order to excel their beneficial properties by extending shelf life, preventing products from freezing and developing crusts on the surface.
One important factor is Glyceryl monostearate allows oils to be added to products but decreases the greasiness so the final product is a smooth, creamy texture.

Glyceryl Monostearate plays a crucial role in improving the texture, stability, and appearance of various products in different industries.
Glyceryl monostearate is an effective emulsifier, helping to combine water-based and oil-based ingredients.
It is made by reacting glycerin with stearic acid, which is derived from animal and vegetable fats and oils.

In the production of Glyceryl monostearate, an excess of stearic acid is reacted with glycerin, and then the excess stearic acid is further reacted with potassium and/or sodium hydroxide to produce a product containing glyceryl monostearate along with potassium stearate and/or sodium stearate.
Glyceryl monostearate is known for its nourishing properties, as it deeply restores moisture to the skin.

Glyceryl monostearate also has hydrating effects and aids in emulsification.
The chemical formula of glyceryl monostearate is C21H42O4, and its IUPAC name is 2,3-dihydroxypropyl octadecanoate.
Glyceryl monostearate is soluble in hot alcohol, chloroform, benzene, and carbon disulfide, but insoluble in water, petroleum ether, ether, and cold ethanol.

When handling glyceryl monostearate, proper personal protective equipment should be used, such as gloves and eye protection.
Glyceryl monostearate should be stored in a sealed container at a temperature of -20 °C.

Uses
Glyceryl monostearate is an emulsifier that helps form neutral, stable emulsions.
Glyceryl monostearate is also a solvent, humectant, and consistency regulator in water-in-oil and oil-in-water formulations.
Glyceryl monostearate can be used as a skin lubricant and imparts a pleasant skin feel.

Glyceryl monostearate is a mixture of mono-, di-, and triglycerides of palmitic and stearic acids, and is made from glycerin and stearic fatty acids.
Derived for cosmetic use from palm kernel or soy oil, it is also found in the human body.
Glyceryl monostearate is very mild with a low skin-irritation profile; however, a slight risk of irritation exists if products contain poor quality glyceryl stearate.

Commercial material used in foods is produced industrially by a Glyceryl monostearate is reaction between triglycerides (from either vegetable or animal fats) and glycerol.
Glyceryl monostearate is also used as an emulsifying agent for oils, waxes, and solvents, a protective coating for hygroscopic powders, a solidifier and controlled release agent in pharmaceuticals, and a lubricant in cosmetics and hair-care products.

Glyceryl monostearate is a self emulsifying nonionic surfactant, used as a lubricant in confectionery, as a release agent and as a dough softener.
Glyceryl monostearate is used as a low HLB emulsifier in personal care products where non animal grade products are needed.

Glyceryl monostearate is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.
Glyceryl monostearate is also used in cosmetics and hair-care products.

In the food industry, Glyceryl Monostearate is used as a food additive with multiple functions.
Glyceryl monostearate acts as a thickening agent, emulsifier, anti-caking agent, and preservative.
Glyceryl monostearate helps improve the physical and rheological properties of batters and doughs, resulting in better-quality cakes and bread.

Glyceryl monostearate also enhances the aeration of doughs and batters, contributing to the texture of products like sponge cakes and pancakes.
Glyceryl monostearate is widely used in the food industry as an emulsifier, stabilizer, and thickening agent.
It helps to blend ingredients, prevent separation, and improve texture.

Glyceryl monostearate helps to improve the texture, stability, and shelf life of bread, cakes, cookies, and pastries.
It aids in the formation of a stable emulsion, preventing the formation of ice crystals and improving the smoothness of the ice cream.
Glyceryl monostearate helps to stabilize and emulsify the fat and water components, ensuring a homogeneous product.

Glyceryl monostearate assists in creating a stable emulsion in salad dressings, mayonnaise, and sauces, preventing separation of oil and water.
Glyceryl monostearate is widely used in cosmetics and personal care products due to its emulsifying, stabilizing, and thickening properties.
It can be found in various products, including:

Glyceryl monostearate helps to combine oil and water-based ingredients, creating a smooth texture and preventing separation.
Glyceryl monostearate contributes to the creamy consistency and helps to retain moisture in the skin.
It aids in the formation of stable emulsions and provides a smooth texture to shampoos, conditioners, and styling products.

In pharmaceutical formulations, glyceryl monostearate is used as a binder, solubilizer, and lubricant in tablet and capsule preparations.
Glyceryl monostearate helps to improve the cohesion and compressibility of powdered ingredients in tablets, enhances drug solubility, and reduces friction during tablet manufacturing.

Glyceryl Monostearate is commonly used in the production of dairy products such as cream, whipped cream, ice cream, and imitation creams.
Glyceryl monostearate is also utilized in fruit/vegetable spreads, jams, jellies, and marmalades.
Glyceryl monostearate is employed in cosmetics and hair care products, serving as an emulsifying agent, emollient, and surfactant in various formulations.

In pharmaceuticals, Glyceryl Monostearate can be used as a solidifier, control release agent, and protective coating for hygroscopic powders.
It is also found in certain plastics used for food packaging and can be used as an emulsifier in PVC and other polymer processing.
Glycerol monostearate is used as an emulsifier, resin lubricant, opacifier, emollient, bodying agent in a variety of cosmetic formulations for skincare and haircare.

Glyceryl monostearate is also used as a thickening, anti-caking and preservative agent.
Glyceryl monostearate is also useful for preventing ice creams from drying out or being too sweet.
It is further used as a foaming agent for the foam-mat drying of papaya.

Glyceryl monostearate is also used as an anti-staling agent in bread.
Glyceryl monostearate is largely used in baking preparations to add "body" to the food.
Glyceryl monostearate is somewhat responsible for giving ice cream and whipped cream their smooth texture.

Glyceryl monostearate is sometimes used as an antistaling agent in bread.
Glyceryl monostearate is used in the following products: washing & cleaning products, lubricants and greases, adhesives and sealants, polishes and waxes, fertilisers and coating products.

Other release to the environment of Glyceryl monostearate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Glyceryl monostearate is utilized in pharmaceuticals beyond tablet and capsule formulations.
It can be found in various medications and medical products in different forms, including creams, ointments, and suppositories.
Glyceryl monostearate serves as an emulsifier, stabilizer, and consistency regulator, ensuring the uniform distribution and stability of active pharmaceutical ingredients (APIs) and other components.

Glyceryl monostearate is also used as a food additive in certain products to provide specific characteristics. Some examples include:
Glyceryl monostearate aids in the prevention of fat bloom, which is the migration of cocoa butter to the surface of chocolate, resulting in discoloration or a dull appearance.
Whipped toppings: It helps stabilize the foam structure, providing a light and fluffy texture.

Glyceryl monostearate assists in emulsifying and stabilizing the fat and water components, creating a creamy texture and preventing separation.
Glyceryl monostearate finds applications in various industrial processes as well.
Glyceryl monostearate is used as a lubricant, release agent, and anti-static agent in industries such as plastics, rubber, and textiles.

Glyceryl monostearate can help improve the flow properties of materials and prevent adhesion or sticking during manufacturing processes.
Glyceryl monostearate can be found in certain nutritional supplements, particularly those in the form of powders or capsules.
Glyceryl monostearate is used as an emulsifier and stabilizer to improve the dispersibility and mixability of powdered supplements.

Glyceryl monostearate helps prevent clumping and ensures uniform distribution of the active ingredients.
Glyceryl monostearate is commonly used in the production of bakery and confectionery items to improve their texture, shelf life, and overall quality.
It aids in dough conditioning, emulsification of fats, and stabilization of air bubbles during baking.

Glyceryl monostearate is also used in certain confectionery coatings, fillings, and icings to provide a smooth texture and prevent oil separation.
Glyceryl monostearate can be used in the production of dairy products to enhance their texture and stability.
It is often added to products like yogurt, cheese, and cream to improve their smoothness, prevent syneresis (the separation of liquid), and provide a creamy mouthfeel.

Glyceryl monostearate is utilized in the manufacturing of pet food, particularly in the production of dry kibbles.
Glyceryl monostearate helps improve the extrusion process, bind the ingredients together, and maintain the structural integrity of the kibble.

In industrial applications, glyceryl monostearate is used as a lubricant and anti-static agent.
It can be found in lubricants for machinery, metalworking processes, and other industrial equipment.
Its lubricating properties help reduce friction, wear, and heat generation.

Glyceryl monostearate is sometimes included in animal feed and veterinary products.
It can serve as a pelleting aid, improving the binding and durability of animal feed pellets.
Glyceryl monostearate may be used in certain veterinary formulations for oral or topical administration.

Glyceryl monostearate can also be used as an additive in plastic, where GMS works as an antistatic and antifogging agent.
Glyceryl monostearate is common in food packaging.
Glycerol monostearate is used as an emulsifier, resin lubricant, opacifier, emollient, bodying agent in a variety of cosmetic formulations for skincare and haircare.

Glyceryl monostearate is also used as a thickening, anti-caking and preservative agent.
Glyceryl monostearate is also useful for preventing ice creams from drying out or being too sweet.
Glyceryl monostearate is further used as a foaming agent for the foam-mat drying of papaya. It is also used as an anti-staling agent in bread.

Production Methods
Glyceryl monostearate is prepared by the reaction of glycerin with triglycerides from animal or vegetable sources, producing a mixture of monoglycerides and diglycerides.
The Glyceryl monostearate may be further reacted to produce the 90% monoglyceride grade.
Another process involves reaction of glycerol with stearoyl chloride.

The starting materials are not pure Glyceryl monostearate and therefore the products obtained from the processes contain a mixture of esters, including palmitate and oleate. Consequently, Glyceryl monostearate, and therefore the physical properties, of glyceryl monostearate may vary considerably depending on the manufacturer.

Pharmaceutical Applications
The many varieties of glyceryl monostearate are used as nonionic emulsifiers, stabilizers, emollients, and plasticizers in a variety of food, pharmaceutical, and cosmetic applications.
Glyceryl monostearate acts as an effective stabilizer, that is, as a mutual solvent for polar and nonpolar compounds that may form water-in-oil or oil-in-water emulsions.

These properties also make it useful as a dispersing agent for pigments in oils or solids in fats, or as a solvent for phospholipids, such as lecithin.
Glyceryl monostearate has also been used in a novel fluidized hot-melt granulation technique for the production of granules and tablets.

Glyceryl monostearate is a lubricant for tablet manufacturing and may be used to form sustained-release matrices for solid dosage forms.
Sustained-release applications include the formulation of pellets for tablets or suppositories, and the preparation of a veterinary bolus.

Glyceryl monostearate has also been used as a matrix ingredient for a biodegradable, implantable, controlledrelease dosage form.
When using glyceryl monostearate in a formulation, the possibility of polymorph formation should be considered.
The aform is dispersible and foamy, useful as an emulsifying agent or preservative.

The denser, more stable, b-form is suitable for wax matrices.
Glyceryl monostearate has been used to mask the flavor of clarithromycin in a pediatric formulation.

Storage
If stored at warm temperatures, glyceryl monostearate increases in acid value upon aging owing to the saponification of the ester with trace amounts of water.
Glyceryl monostearate should be stored in a tightly closed container in a cool, dry place, and protected from light.

Skin and Eye Irritation
Undiluted or concentrated glyceryl monostearate may cause skin and eye irritation in some individuals.
Direct contact with the skin or eyes should be avoided, and appropriate protective measures such as gloves and goggles should be used when handling concentrated forms.

Allergic Reactions
Some people may have allergies or sensitivities to glyceryl monostearate.
If an individual is known to have allergic reactions to Glyceryl monostearate or has experienced adverse effects in the past, it is advisable to consult a healthcare professional or allergist before using products containing glyceryl monostearate.

Inhalation
Inhalation of powdered forms or aerosolized glyceryl monostearate should be avoided as it may cause respiratory irritation.
Glyceryl monostearate is important to handle and use the substance in well-ventilated areas.

Environmental Impact
While glyceryl monostearate is biodegradable, excessive or improper disposal of large quantities can have adverse effects on the environment.
Glyceryl monostearate is recommended to follow local regulations for the safe disposal of glyceryl monostearate and related substances.

Synonyms
Glyceryl monostearate
123-94-4
Monostearin
31566-31-1
GLYCEROL MONOSTEARATE
Glyceryl stearate
Tegin
1-Stearoyl-rac-glycerol
1-MONOSTEARIN
Glycerin 1-monostearate
Stearin, 1-mono-
Stearic acid 1-monoglyceride
2,3-dihydroxypropyl octadecanoate
Glycerol 1-monostearate
1-Glyceryl stearate
Glycerin 1-stearate
Sandin EU
1-Monostearoylglycerol
Octadecanoic acid, 2,3-dihydroxypropyl ester
Aldo MSD
Aldo MSLG
Glyceryl 1-monostearate
Stearoylglycerol
Glycerol 1-stearate
alpha-Monostearin
Tegin 55G
Emerest 2407
Aldo 33
Aldo 75
Glycerin monostearate
Arlacel 165
3-Stearoyloxy-1,2-propanediol
Cerasynt SD
Stearin, mono-
.alpha.-Monostearin
Monoglyceryl stearate
Glycerol alpha-monostearate
Cefatin
Dermagine
Monelgin
Sedetine
Admul
Orbon
Citomulgan M
2,3-Dihydroxypropyl stearate
Drewmulse V
Cerasynt S
Drewmulse TP
Tegin 515
Cerasynt SE
Cerasynt WM
Cyclochem GMS
Drumulse AA
Protachem GMS
Witconol MS
Witconol MST
FEMA No. 2527
Glyceryl stearates
Monostearate (glyceride)
Unimate GMS
Glyceryl monooctadecanoate
Ogeen M
Emcol CA
Emcol MSK
Hodag GMS
Ogeen GRB
Ogeen MAV
Aldo MS
Aldo HMS
Armostat 801
Kessco 40
Stearic monoglyceride
Abracol S.L.G.
Arlacel 161
Arlacel 169
Imwitor 191
Imwitor 900K
NSC 3875
Atmul 67
Atmul 84
Starfol GMS 450
Starfol GMS 600
Starfol GMS 900
Cerasynt 1000-D
Emerest 2401
Aldo-28
Aldo-72
Atmos 150
Atmul 124
Estol 603
Ogeen 515
Tegin 503
Grocor 5500
Grocor 6000
Glycerol stearate, pure
Stearic acid alpha-monoglyceride
Cremophor gmsk
Glyceryl 1-octadecanoate
Cerasynt-sd
Lonzest gms
Cutina gms
Lipo GMS 410
Lipo GMS 450
Lipo GMS 600
glycerol stearate
1-MONOSTEAROYL-rac-GLYCEROL
Nikkol mgs-a
Glyceryl monopalmitostearate
USAF KE-7
1-octadecanoyl-rac-glycerol
EMUL P.7
EINECS 204-664-4
EINECS 245-121-1
UNII-230OU9XXE4
Celinhol - A
Stearic acid, monoester with glycerol
Glycerol .alpha.-monostearate
Glyceroli monostearas
Myvaplex 600
Glycerol monostearate, purified
Imwitor 491
Sorbon mg-100
22610-63-5
Cithrol gms 0400
UNII-258491E1RZ
NSC3875
Stearic acid .alpha.-monoglyceride
(1)-2,3-Dihydroxypropyl stearate
MONOSTEARIN (L)
C21H42O4
NSC-3875
1-Monooctadecanoylglycerol
EINECS 250-705-4
1,2,3-Propanetriol monooctadecanoate
Octadecanoic acid, ester with 1,2,3-propanetriol
GLYCERYL 1-STEARATE
TEGIN 90
1-O-Octadecanoyl-2n-glycerol
AI3-00966
MG(18:0/0:0/0:0)[rac]
230OU9XXE4
DTXSID7029160
Glyceryl monostearate [JAN:NF]
CHEBI:75555
EC 250-705-4
GLYCERYL MONOSTEARATE 40-50
Octadecanoic acid, monoester with 1,2,3-propanetriol
258491E1RZ
1-Stearoyl-rac-glycerol (90per cent)
83138-62-9
85666-92-8
NCGC00164529-01
(+/-)-2,3-DIHYDROXYPROPYL OCTADECANOATE
DTXCID909160
Octadecanoic acid, 2,3-dihydroxypropyl ester, (A+/-)-
MFCD00036186
CAS-123-94-4
rac-Glycerol 1-stearate
EINECS 238-880-5
1-Monooctadecanoyl-rac-glycerol
Celinhol-A
MG 18:0
(+/-)-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
Eastman 600
1-O-stearoylglycerol
1-octadecanoylglycerol
Glycerol Mono Stearate
rac-octadecanoylglycerol
glycerol 1-octadecanoate
rac-glyceryl monostearate
Glycerol .alpha.-sterate
rac-1-monostearoylglycerol
DSSTox_CID_9160
Dur-Em 117
Monoglycerides, c16-18
(+-)-1-stearoylglycerol
SCHEMBL4488
(+-)-glyceryl monostearate
Geleol mono and diglycerides
DSSTox_RID_78757
DSSTox_GSID_29304
Glycerol monostearate (GMS)
(+-)-1-monostearoylglycerol
(+-)-1-octadecanoylglycerol
Glycerides, C16-18 mono-
Glycerol monostearate 40-55
GLYCERYL STEARATE (II)
CHEMBL255696
2,3-Dihydroxypropyl stearate #
DTXSID7027968
CHEBI:75557
1-Stearoyl-rac-glycerol (90%)
GLYCERYL MONOSTEARATE (II)
Glyceryl monostearate (JP17/NF)
1-Stearoyl-rac-glycerol, >=99%
MAG 18:0
(+-)-2,3-dihydroxypropyl stearate
EINECS 293-208-8
Tox21_112160
Tox21_202573
Tox21_301104
LMGL01010003
rac-2,3-dihydroxypropyl octadecanoate
AKOS015901589
STEARATE, 2,3-DIHYDROXYPROPYL
Tox21_112160_1
DB11250
(+-)-2,3-dihydroxypropyl octadecanoate
NCGC00164529-02
NCGC00164529-03
NCGC00164529-04
NCGC00255004-01
NCGC00260122-01
Octadecanoic acid,3-dihydroxypropyl ester
1,2,3-Propanetriol 1-octadecanoyl ester
BS-50505
STEARATE, 2,3-DIHYDROXYPROP-1-YL
C18-H36-O2.(C3H8-O3)x-
CAS-11099-07-3
LS-164168
FT-0626740
FT-0626748
FT-0674656
G0085
Octadecanoic acid, 2.3-dihydroxypropyl ester
C18-H36-O2.x-(C3-H8-O3)x-
D01947
EC 293-208-8
F71433
S-7950
500-265-7 (NLP #)
A890632
A903419
SR-01000944874
Octadecanoic acid monoester with 1,2,3-propanetriol
Octadecanoic acid, monester with 1,2,3-propanetriol
Q-201168
Q5572563
SR-01000944874-1
W-110285
Glyceryl monostearate; (Octadecanoic acid, monoester with 1,2,3-propanetriol)
()-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
342394-34-7
37349-34-1
8029-22-9
Octadecanoic acid, monoester with 3,3'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(1,2-propanediol-

DESCRIPTION:
Glyceryl monostearate, commonly known as GMS, is a monoglyceride commonly used as an emulsifier in foods.
Glyceryl monostearate takes the form of a white, odorless, and sweet-tasting flaky powder that is hygroscopic.
Chemically Glyceryl monostearate is the glycerol ester of stearic acid.

CAS Number: 31566-31-1
European Community (EC) Number: 250-705-4
Molecular Formula: C21H42O4

Glyceryl monostearate is also used as hydration powder in exercise formulas
Glyceryl monostearate (GMS) is an effective emulsifier used in the baking industry available in the form of small beads, flakes, or powders.

In addition to emulsification, GMS is a thickening agent and a stabilizer.
In baking, Glyceryl monostearate (GMS) is used to improve dough quality and stabilize fat/protein emulsions.


1-monostearoylglycerol is a 1-monoglyceride that has stearoyl as the acyl group.
Glycerol monostearate has a role as an algal metabolite and a Caenorhabditis elegans metabolite.

Glycerol monostearate, commonly known as GMS, is the glycerol ester of stearic acid .
Glycerol monostearate is commonly used as an emulsifier in foods.
Glyceryl monostearate is a natural product found in Aristolochia cucurbitifolia, Lobelia longisepala, and other organisms with data available.



GMS (Glyceryl Monostearate) acts as an emulsifying agent.
Glyceryl monostearate is a non-ionic, modified and self-emulsifying glyceryl monostearate.
Glyceryl monostearate is used individually or in combination with other chemicals.

Moreover, Glyceryl monostearate is compatible with electrolytes and variety of cosmetic active ingredients.
GMS (Glyceryl Monostearate) finds application in formulating oil in water (O/W) emulsions.
Glyceryl monostearate has a shelf life of 3 years.




STRUCTURE, SYNTHESIS, AND OCCURRENCE OF GLYCERYL MONOSTEARATE (GMS):
Glyceryl monostearate exists as three stereoisomers, the enantiomeric pair of 1-glycerol monostearate and 2-glycerol monostearate.
Typically these are encountered as a mixture as many of their properties are similar.

Commercial material used in foods is produced industrially by a glycerolysis reaction between triglycerides (from either vegetable or animal fats) and glycerol.
Glyceryl monostearate occurs naturally in the body as a product of the breakdown of fats by pancreatic lipase.
Glyceryl monostearate is present at very low levels in certain seed oils.

USES OF GLYCERYL MONOSTEARATE(GMS):
Glyceryl monostearate is a food additive used as a thickening, emulsifying, anticaking, and preservative agent; an emulsifying agent for oils, waxes, and solvents; a protective coating for hygroscopic powders; a solidifier and control release agent in pharmaceuticals; and a resin lubricant.
Glyceryl monostearate is also used in cosmetics and hair-care products.

Glyceryl monostearate is largely used in baking preparations to add "body" to the food.
Glyceryl monostearate is somewhat responsible for giving ice cream and whipped cream their smooth texture.
Glyceryl monostearate is sometimes used as an antistaling agent in bread.

Glyceryl monostearate can also be used as an additive in plastic, where GMS works as an antistatic and antifogging agent.
Glyceryl monostearate is common in food packaging.



ORIGIN OF GLYCERYL MONOSTEARATE(GMS):
The first known emulsifier was egg yolk, often used to disperse liquid oil into an acidic aqueous phase.
Mono- and diglycerides were first synthesized in 1853 and were extensively used in shortening and margarine formulations by the 1930s.

COMPOSITION OF GLYCERYL MONOSTEARATE(GMS):
Glyceryl monostearate (GMS) is a non-ionic ester of glycerol and stearic acid.
Glyceryl monostearate (GMS) is soluble in ethanol at 122°F (50°C) but immiscible with water.
Glyceryl monostearate (GMS) often consists of a mixture of mono, di, and triesters of fatty acids occurring in food oils and fats.

They may contain small amounts of free fatty acids and glycerol.

COMMERCIAL PRODUCTION OF GLYCERYL MONOSTEARATE(GMS):
GMS is produced either through heating oils/fats with excess glycerol or by direct esterification of glycerol (of animal or plant sources) with stearic acid.
The proportion of monoester formed is dependent on the proportion of glycerol and reaction temperature range of 86-140°F (60-80°C).
Further purification is carried out by high vacuum distillation.


FUNCTION OF GLYCERYL MONOSTEARATE(GMS):
The ratio of hydrophilic to lipophilic moieties, called hydrophilic-lipophilic balance (HLB) is used in classifying emulsions.
HLB values range from 0-20 with lower values indicating dominant lipophilic character while higher values indicate hydrophilic character.
Glyceryl monostearate (GMS) has a HLB value of 3.8, making it lipophilic and suitable for uses in w/o emulsions, such as batters and doughs, dairy and other products.


Glyceryl monostearate (GMS) is used in a paste form, i.e. mixed with water and other ingredients to improve gel stability.
Glyceryl monostearate (GMS) is an unsaturated monoglyceride and offers better stability than other unsaturated monoglycerides, such as oleic acid.
Glyceryl monostearate (GMS) is used in the baking industry to:

Glyceryl monostearate (GMS) Help in the formation and maintenance of uniform dispersions of immiscible solvents.
Glyceryl monostearate (GMS) Stabilize emulsions via displacing proteins from oil, wax or solvent surfaces.

Glyceryl monostearate (GMS) Improve bread texture, and retard staling due to its complexation with starch amylopectin
Glyceryl monostearate (GMS) Improve aeration of doughs and batters.


APPLICATIONS OF GLYCERYL MONOSTEARATE (GMS):
Glyceryl monostearate (GMS) has been used in the following applications:
Glyceryl monostearate (GMS) has been used To improve the physical and rheological properties of the batter and thus better-quality cakes
Glyceryl monostearate (GMS) has been used In breads such as pain courant Français, Friss búzakenyér, naan and roti

Glyceryl monostearate (GMS) has been used In sponge cakes and pancakes for aeration.
Glyceryl monostearate (GMS) has been used Dairy products such as cream, whipped cream, ice cream, cream powder, imitation creams, etc.
Glyceryl monostearate (GMS) has been used Fruit/vegetable spreads, jams, jellies, marmalades




CHEMICAL AND PHYSICAL PROPERTIES OF GLYCERYL MONOSTEARATE (GMS):
Chemical formula C21H42O4
Molar mass 358.563 g•mol−1
Appearance White solid
Density 1.03 g/cm3
Melting point (Mix) 57–65 °C (135–149 °F)
(1-) 81 °C (178 °F)
(2-) 73–74 °C (163–165 °F)
Solubility in water Insoluble
Molecular Weight 358.6 g/mol
XLogP3 7.4
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Rotatable Bond Count 20
Exact Mass 358.30830982 g/mol
Monoisotopic Mass 358.30830982 g/mol
Topological Polar Surface Area 66.8Ų
Heavy Atom Count 25
Formal Charge 0
Complexity 281
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 1
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes


SAFETY INFORMATION ABOUT GLYCERYL MONOSTEARATE (GMS):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
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SYNONYMS OF GLYCERYL MONOSTEARATE (GMS):
glyceryl monostearate
monostearin
Glyceryl monostearate
123-94-4
Monostearin
GLYCEROL MONOSTEARATE
31566-31-1
Glyceryl stearate
Tegin
1-Stearoyl-rac-glycerol
1-MONOSTEARIN
Glycerin 1-monostearate
Stearin, 1-mono-
Stearic acid 1-monoglyceride
2,3-dihydroxypropyl octadecanoate
Glycerol 1-monostearate
1-Glyceryl stearate
Glycerin 1-stearate
Sandin EU
1-Monostearoylglycerol
Octadecanoic acid, 2,3-dihydroxypropyl ester
Aldo MSD
Aldo MSLG
Glyceryl 1-monostearate
Stearoylglycerol
Glycerol 1-stearate
alpha-Monostearin
Tegin 55G
Emerest 2407
Aldo 33
Aldo 75
Arlacel 165
3-Stearoyloxy-1,2-propanediol
Cerasynt SD
Stearin, mono-
2,3-Dihydroxypropyl stearate
.alpha.-Monostearin
Monoglyceryl stearate
Glycerol alpha-monostearate
Cefatin
Dermagine
Monelgin
Sedetine
Admul
Orbon
Citomulgan M
Drewmulse V
Cerasynt S
Drewmulse TP
Tegin 515
Cerasynt SE
Cerasynt WM
Cyclochem GMS
Drumulse AA
Protachem GMS
Witconol MS
Witconol MST
FEMA No. 2527
Glyceryl stearates
Monostearate (glyceride)
Unimate GMS
Glyceryl monooctadecanoate
Ogeen M
Emcol CA
Emcol MSK
Hodag GMS
Ogeen GRB
Ogeen MAV
Aldo MS
Aldo HMS
Armostat 801
Kessco 40
Stearic monoglyceride
Abracol S.L.G.
Arlacel 161
Arlacel 169
Imwitor 191
Imwitor 900K
NSC 3875
11099-07-3
Atmul 67
Atmul 84
Starfol GMS 450
Starfol GMS 600
Starfol GMS 900
Cerasynt 1000-D
Emerest 2401
Aldo-28
Aldo-72
Atmos 150
Atmul 124
Estol 603
Ogeen 515
Tegin 503
Grocor 5500
Grocor 6000
Glycerol stearate, pure
Stearic acid alpha-monoglyceride
Cremophor gmsk
Glyceryl 1-octadecanoate
Cerasynt-sd
Lonzest gms
Cutina gms
Lipo GMS 410
Lipo GMS 450
Lipo GMS 600
glycerol stearate
1-MONOSTEAROYL-rac-GLYCEROL
Nikkol mgs-a
Glyceryl monopalmitostearate
USAF KE-7
1-octadecanoyl-rac-glycerol
EMUL P.7
EINECS 204-664-4
EINECS 245-121-1
UNII-230OU9XXE4
Stearic acid, monoester with glycerol
Glycerol .alpha.-monostearate
Glyceroli monostearas
Glycerol monostearate, purified
Imwitor 491
Sorbon mg-100
22610-63-5
Cithrol gms 0400
UNII-258491E1RZ
NSC3875
Stearic acid .alpha.-monoglyceride
(1)-2,3-Dihydroxypropyl stearate
MONOSTEARIN (L)
C21H42O4
NSC-3875
1-Monooctadecanoylglycerol
EINECS 250-705-4
1,2,3-Propanetriol monooctadecanoate
Octadecanoic acid, ester with 1,2,3-propanetriol
GLYCERYL 1-STEARATE
1-O-Octadecanoyl-2n-glycerol
AI3-00966
MG(18:0/0:0/0:0)[rac]
230OU9XXE4
DTXSID7029160
CHEBI:75555
EC 250-705-4
GLYCERYL MONOSTEARATE 40-50
Octadecanoic acid, monoester with 1,2,3-propanetriol
258491E1RZ
1-Stearoyl-rac-glycerol (90per cent)
83138-62-9
NCGC00164529-01
(+/-)-2,3-DIHYDROXYPROPYL OCTADECANOATE
DTXCID909160
Octadecanoic acid, 2,3-dihydroxypropyl ester, (A+/-)-
MFCD00036186
Celinhol - A
CAS-123-94-4
GMS
Myvaplex 600
rac-Glycerol 1-stearate
1-Monooctadecanoyl-rac-glycerol
Celinhol-A
Glyceryl monostearate [JAN:NF]
MG 18:0
(+/-)-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
Eastman 600
1-O-stearoylglycerol
1-octadecanoylglycerol
85666-92-8
rac-octadecanoylglycerol
glycerol 1-octadecanoate
rac-glyceryl monostearate
Glycerol .alpha.-sterate
rac-1-monostearoylglycerol
DSSTox_CID_9160
Monoglycerides, c16-18
(+-)-1-stearoylglycerol
SCHEMBL4488
(+-)-glyceryl monostearate
Geleol mono and diglycerides
DSSTox_RID_78757
DSSTox_GSID_29304
Glycerol monostearate (GMS)
(+-)-1-monostearoylglycerol
(+-)-1-octadecanoylglycerol
Glycerides, C16-18 mono-
Glycerol monostearate 40-55
GLYCERYL STEARATE (II)
CHEMBL255696
2,3-Dihydroxypropyl stearate #
DTXSID7027968
CHEBI:75557
1-Stearoyl-rac-glycerol (90%)
GLYCERYL MONOSTEARATE (II)
Glyceryl monostearate (JP17/NF)
1-Stearoyl-rac-glycerol, >=99%
MAG 18:0
EINECS 238-880-5
EINECS 293-208-8
Tox21_112160
Tox21_202573
Tox21_301104
LMGL01010003
rac-2,3-dihydroxypropyl octadecanoate
AKOS015901589
Tox21_112160_1
DB11250
(+-)-2,3-dihydroxypropyl octadecanoate
NCGC00164529-02
NCGC00164529-03
NCGC00164529-04
NCGC00255004-01
NCGC00260122-01
Octadecanoic acid,3-dihydroxypropyl ester
1,2,3-Propanetriol 1-octadecanoyl ester
BS-50505
CAS-11099-07-3
FT-0626740
FT-0626748
FT-0674656
G0085
Octadecanoic acid, 2.3-dihydroxypropyl ester
D01947
EC 293-208-8
F71433
S-7950
A890632
A903419
SR-01000944874
Q-201168
Q5572563
SR-01000944874-1
W-110285
()-2,3-Dihydroxypropyl octadecanoate; 1-Glyceryl stearate; 1-Monooctadecanoylglycerol; 1-Monostearin
342394-34-7
InChI=1/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H

SYNONYMS Glycerol Oleate; Glyceryl Monooleate; Glyceryl oleate; (Z)-1-Oleoyl-sn-glycerol; 1,2,3-propanetriol, 9-Octadecenoic acid; Glycerol Monoleate; Monoolein;cas: 25496-72-4

Glycerol Oleate; Glyceryl Monooleate; Glyceryl oleate; (Z)-1-Oleoyl-sn-glycerol; 1,2,3-propanetriol, 9-Octadecenoic acid; Glycerol Monoleate; Monoolein; cas no: 25496-72-4

Glyceryl palmitate is naturally derived from dairy products such as butter, cheese, animal products, egg yolks, palm oil and palm kernel oil.
Glyceryl palmitate is also found in the human body.
Glyceryl palmitate comes as a yellowish-white to white solid.

CAS Number: 26657-96-5
Molecular Formula: C19H38O4
Molecular Weight: 330.503
EINECS Number: 247-887-2

Glyceryl Palmitate, 247-887-2, 6Y2XJ05B35, D-2447, Palmitic Acid Monoglyceride, 1330-73-0, D 2447, DREWMULSE DA, EMALSY P 100, GLYCERIN MONOPALMITATE, GLYCERYL PALMITATE (II), MONOPALMITOYL-RAC-GLYCEROL, MONOPALMITOYLGLYCEROL, PALMITIC MONOGLYCERIDE, PALMITIN, MONO-, POEM PV 100, RIKEMAL P 100, RYLO-MG 16, SUNSOFT 8001

Glyceryl palmitate is a 1-monoglyceride that has palmitoyl as the acyl group.
A natural Glyceryl palmitate found in Neolitsea daibuensis.
Glyceryl palmitate has a role as a plant metabolite and an algal metabolite.

Glyceryl palmitate is functionally related to a hexadecanoic acid.
Glyceryl palmitate is one of the components of glycerol monoesters.
Glyceryl palmitate is made from glycerin and palmitic acid.

Glyceryl palmitate in the name means that it is a self-emulsifying grade that contains some sodium and/or potassium salts of the acid.
Glyceryl palmitates are primarily used in the formulation of creams and lotions, moisturizers, and other skin care products, but glyceryl monoesters can also be found in permanent waves, deodorants, bath soaps, eye makeup and foundations.
Glyceryl palmitate is a member of the chemical class known as Monoacylglycerols.

Glyceryl palmitate is found in fats and oils. Glycerol 1-hexadecanoate is a minor component of olive oil and other vegetable oil.
Glyceryl palmitate is a glycerol esterified fatty acid, monoacylglycerol, found in lipid structures such as ceramides.
Glyceryl palmitate may be used as a substrate for the identification and differentiation of enzymes that hydrolyze or transfer monoacylglycerols such as neuropathy target esterase(s) and monoacylglycerol acyltransferase(s) (MAG).

Glyceryl palmitate, also known as glyceryl monopalmitate, is a fatty acid ester that is widely used in the food, cosmetic, and pharmaceutical industries.
Glyceryl palmitate is synthesized by esterification of palmitic acid with glycerol and has a wide range of applications due to its unique properties.
Glyceryl palmitate is an ester derived from palmitic acid and glycerol.

Glyceryl palmitate belongs to the class of compounds known as glycerides, specifically monoacylglycerols.
In its molecular structure, glyceryl palmitate consists of a glycerol molecule esterified with three fatty acid chains, one of which is palmitic acid.
Glyceryl palmitate uses and applications include: Emollient for cosmetics; surfactant, emulsifier for foods, cosmetics, pharmaceuticals

Glyceryl palmitate is a white to cream-colored solid or waxy substance.
Glyceryl palmitate is typically soluble in organic solvents but has limited solubility in water.
In cosmetics and personal care products, glyceryl palmitate serves various functions.

Glyceryl palmitate softens and smoothens the skin, providing a moisturizing effect.
Glyceryl palmitate contributes to the viscosity and texture of cosmetic formulations.
Glyceryl palmitate helps stabilize emulsions, preventing separation of oil and water components in creams and lotions.

Glyceryl palmitate has emulsifying properties, making it useful in the creation and stabilization of oil-in-water emulsions.
This property is valuable in both cosmetic and food applications.
Glyceryl palmitate can be synthesized for various applications, it is also found naturally in some animal and plant sources, particularly in fats and oils.

Various derivatives of glyceryl palmitate can be synthesized or modified for specific applications in different industries.
Glyceryl palmitate is generally recognized as safe (GRAS) for use in food by regulatory authorities, and it is approved for use in cosmetics and personal care products.
However, regulations may vary by region, so it's essential to comply with local guidelines.

Generally, glyceryl palmitate is considered biodegradable, which is a favorable characteristic from an environmental perspective.
While glyceryl palmitate is considered safe for most people, individuals with sensitive skin may want to be cautious, as with any cosmetic ingredient.
Always perform patch tests when trying new products.

Glyceryl palmitate can undergo hydrolysis in the presence of water and lipases, breaking down into glycerol and palmitic acid.
This process is a natural part of lipid metabolism in the body.
Glyceryl palmitate is a member of the glycerides family, which includes various compounds formed by the combination of glycerol with fatty acids.

Other glycerides include glyceryl stearate, glyceryl oleate, and more, each with its unique properties.
Glyceryl palmitate is often used in combination with other emollients, thickeners, and stabilizers to achieve synergistic effects in cosmetic and personal care formulations.
Due to its stability, glyceryl palmitate is often found in products with longer shelf lives.

Proper packaging and storage conditions, such as avoiding exposure to excessive heat and light, can help maintain its quality.
Glyceryl palmitate is generally compatible with a wide range of cosmetic ingredients, allowing formulators flexibility in creating various skincare and personal care products.
In certain formulations, glyceryl palmitate might be replaced or complemented by other esters or emollients, depending on the desired characteristics of the final product.

Ongoing research in cosmetic science and formulation may lead to innovations in the use of glyceryl palmitate, as well as the development of new derivatives or combinations for improved performance.
Due to its versatility and widespread acceptance, glyceryl palmitate is used in cosmetic and personal care products globally, contributing to its presence in a variety of skincare and beauty items.

Melting point: 72.5-73 °C
LogP: 6.166 (est)

Glyceryl palmitate is primarily a combination of glycerin and a single molecule of palmitic acid.
Glyceryl palmitate has the dual benefits of glycerin and palmitic acid. When applied, it forms a layer on the skin that protects the skin from external harmful influences and preserves skin moisture.
This way the skin becomes smoother and softer.

For dry skin, when applied to the skin, Glyceryl palmitate soothes and nourishes the skin.
May be an intermediary between the oil phase and the water phase.
Since it can combine with oil-loving molecules and water-loving molecules and mix both evenly to form a stable emulsion.

Glyceryl palmitate also acts as a surfactant, forming a foam when used and also helps clean the surface of the skin or hair.
This ingredient contains glycerol as alcohol component in esters or condensed with other (poly) alcohols or sugars.
Due to its emollient properties and its ability to enhance the texture of cosmetic products, glyceryl palmitate is often incorporated into anti-aging formulations, such as moisturizers and creams.

In dermatology, glyceryl palmitate is sometimes used in formulations designed to address specific skin conditions or as a component in products recommended by dermatologists.
Glyceryl palmitate may be included in hair care products, such as conditioners or styling products, to provide conditioning and smoothing effects to the hair.
Glyceryl palmitate is generally considered biocompatible, making it suitable for use in a variety of cosmetic and personal care products designed for skin application.

In addition to its use in liquid and cream formulations, glyceryl palmitate can also be found in some powdered cosmetic products, contributing to their texture and feel.
Glyceryl palmitate exhibits good photostability, making it suitable for use in formulations that may be exposed to light, such as sunscreen products.
As a derived compound from natural sources, glyceryl palmitate may find use in formulations for natural or organic cosmetic and personal care products.

Glyceryl palmitate is use is sometimes combined with other emollients, such as fatty alcohols or plant-derived oils, to enhance the overall skin-feel and performance of cosmetic products.
Consumer preferences for products with desirable sensory attributes, such as smooth texture and easy application, contribute to the continued use of glyceryl palmitate in various cosmetic formulations.
The sourcing and production of glyceryl palmitate may be subject to sustainability considerations, with some manufacturers opting for responsibly sourced raw materials and eco-friendly production processes.

Glyceryl palmitate can be included in micellar water formulations, which are popular in skincare for their gentle cleansing properties.
Glyceryl palmitate can contribute to the formulation's texture and stability.
Its emollient nature makes glyceryl palmitate suitable for use in cleansing balms and oils, where it helps in breaking down and removing makeup and impurities.

In skincare formulations aimed at supporting the skin barrier function, glyceryl palmitate may be used to enhance moisturization and contribute to the overall health of the skin.
Due to its compatibility with other cosmetic ingredients, glyceryl palmitate is often found in liquid foundations and BB creams, providing a smooth application and a desirable skin finish.
In certain formulations, glyceryl palmitate can serve as a stabilizer for fragrances, contributing to the longevity and consistency of scent in cosmetic and personal care products.

The hydrophobic nature of glyceryl palmitate makes it valuable in formulations where water resistance or repellency is desired, such as in certain sunscreens or water-resistant cosmetic products.
Its use can contribute to the stability of cosmetic formulations, preventing phase separation and maintaining the overall quality of the product over time.
Due to its mild and skin-friendly properties, glyceryl palmitate may be included in formulations for baby care products such as lotions and creams.

Glyceryl palmitate is appreciated for its versatility as it can function as an emollient, thickener, stabilizer, and more in cosmetic and personal care formulations.
Ongoing research may explore innovative delivery systems, such as encapsulation, to optimize the performance of glyceryl palmitate in cosmetic applications.
Palmitate's impact on insulin response: Palmitate has been shown to reduce insulin-stimulated glycogen synthesis and inhibit protein kinase B (PKB) without affecting IRS-1 function, indicating its potential role in insulin resistance mechanisms.

Functionalized poly(glycerol sebacate) with palmitate can alter a polymer's hydrophobicity, crystallinity, microstructures, and thermal properties.
This modification imparts tunable degradation profiles and mechanical properties, making it significant in biomedical engineering.
Glyceryl behenate shows superior encapsulation capabilities for retinoids in solid lipid nanoparticles compared to cetyl palmitate and other substances.

This property is critical for pharmaceutical applications.
Glyceryl palmitate labeling showed increased labeling of various glycolipids in dense cultures, suggesting a possible correlation with cell contact.

Glyceryl palmitate serves as a brood pheromone in drone pupae of the honey bee Apis mellifera L., highlighting its role in insect biology.
Palmitoylation is emerging as a regulator of metabolism and could lead to metabolic impairments found in obesity-related diseases.

Uses:
A mixture of portions of Glyceryl palmitate used as an emollient, surfactant, and emulsifier. May be plant- or animal-derived or synthetic.
Glyceryl palmitate is commonly used in the cosmetic and personal care industry as an emollient, thickening agent, and moisturizer.
Glyceryl palmitate helps improve the texture of creams, lotions, and other formulations.

Glyceryl palmitate can be used as a food additive, often functioning as an emulsifier and stabilizer in various food products.
In pharmaceuticals, Glyceryl palmitate may be used as an excipient or an ingredient in drug formulations.
Enhances the texture of creams, lotions, and cosmetic formulations, providing a smooth and soft feel to the skin.

Contributes to the viscosity of formulations, helping to stabilize and improve the overall texture.
Acts as a moisturizing agent, aiding in skin hydration.
Glyceryl palmitate is used in food products to stabilize emulsions, preventing separation of oil and water phases.

Contributes to the texture and mouthfeel of certain food items.
Applied in food processing for its emulsifying and stabilizing properties.
Glyceryl palmitate utilized as an inactive ingredient or carrier in pharmaceutical formulations, aiding in the consistency and stability of medications.

Included in hair care products, such as conditioners, to improve the texture and manageability of the hair.
Found in skincare formulations aimed at supporting the skin barrier, contributing to overall skin health.
Included in products for makeup removal and cleansing due to its emollient and cleansing properties.

Glyceryl palmitate is used in micellar water formulations for its ability to dissolve and remove impurities.
Included in fragrances to stabilize and extend the scent in cosmetic and personal care products.
Glyceryl palmitate is used in the formulation of gentle baby care products such as lotions and creams.

Valued in formulations where water resistance or repellency is desired, such as certain sunscreens and water-resistant cosmetics.
Ongoing research may explore innovative delivery systems, such as encapsulation, to optimize the performance of glyceryl palmitate in cosmetic applications.
Included in anti-aging skincare formulations, contributing to the overall texture and moisturizing properties of products designed to address signs of aging.

Found in liquid foundations and BB creams to enhance the application and provide a smooth finish on the skin.
Glyceryl palmitate is used in formulations aimed at repairing and supporting the skin barrier function, helping to maintain skin health and integrity.
Included in some powdered cosmetic products to enhance the texture and feel, providing a silky and luxurious finish.

Featured in hydrating face masks to contribute to the overall moisturizing and skin-conditioning effects.
Glyceryl palmitate is used in certain formulations of deodorants and antiperspirants for its emollient and skin-conditioning properties.
Investigated for potential use in encapsulated delivery systems, where active ingredients are encapsulated for controlled release in cosmetic formulations.

Included in some formulations of wound healing creams or ointments for its moisturizing and skin-conditioning properties.
Found in massage oils to enhance the glide and spreadability of the product during massage therapy.
Included in formulations for natural and organic skincare products, aligning with the preferences of consumers seeking more sustainable and natural options.

Glyceryl palmitate utilized in formulations for biodegradable and eco-friendly cosmetic and personal care products, contributing to the environmental sustainability of the formulations.
In some cases, glyceryl palmitate may be included in formulations for dental care products, such as certain toothpaste formulations.
Included in tattoo aftercare products for its skin-conditioning properties, helping to keep the skin moisturized and promote healing.

Included in some shaving creams and gels for its emollient properties, providing a smoother and more comfortable shaving experience.
Found in formulations for foot creams and balms, contributing to the moisturization and overall care of the skin on the feet.
Included in cuticle creams for its skin-conditioning properties, helping to soften and nourish the cuticles.

Glyceryl palmitate is used in certain formulations of nail care products, such as nail creams or oils, for its moisturizing effects on the nails and surrounding skin.
Included in after-sun lotions and creams for its skin-soothing and moisturizing properties, helping to alleviate dryness caused by sun exposure.
Found in various color cosmetics, such as foundations, concealers, and blushes, to improve the texture and application of the products.

Glyceryl palmitate is used in the formulation of lip balms and lipsticks to enhance the smoothness and moisturizing properties on the lips.
Included in certain pre-shampoo treatments or hair masks to provide conditioning benefits to the hair before regular washing.
Found in some formulations of insect repellent creams for its skin-conditioning properties, helping to keep the skin hydrated.

Included in soothing creams designed for irritated or sensitive skin to provide relief and support skin recovery.
Glyceryl palmitate is used in hand lotions and creams for its emollient and moisturizing effects, contributing to softer and smoother hands.
Included in certain body scrub formulations to enhance the texture and overall sensory experience during exfoliation.

Found in some body powder formulations for its contribution to the product's texture and skin-feel.
Investigated for potential use in innovative functional skincare formulations, such as those addressing specific skin concerns or conditions.

Safety Profile:
While glyceryl palmitate is generally well-tolerated, individuals with particularly sensitive skin may want to perform a patch test when trying new products containing this ingredient to rule out any potential adverse reactions.
Contact with the eyes should be avoided, as irritation may occur.

If eye contact occurs, it is recommended to rinse the eyes thoroughly with water.
Inhalation of aerosolized or fine particulate forms of glyceryl palmitate is not typically a concern in normal use scenarios.
However, good manufacturing practices and proper ventilation should be followed.

Ingesting small amounts of glyceryl palmitate, as might occur unintentionally in cosmetic or food products, is generally considered safe.
However, large quantities should be avoided.
While glyceryl palmitate is biodegradable, the environmental impact should be considered.

Glyceryl monostearate; 3-Stearoyloxy-1,2-propanediol; Glyceryl stearate; Alpha-Monostearin; Monostearin; Octadecanoic acid, 2,3-dihydroxypropyl ester; Glycerin 1-monostearate; Glycerin 1-stearate; Glycerol alpha-monostearate; Glyceryl 1-monostearate; Stearic acid alpha-monoglyceride; Stearic acid 1-monoglyceride; 1-Glyceryl stearate; 1-Monostearin; 1-Monostearoylglycerol; 1,2,3-Propanetriol 1-octadecanoyl ester; cas no:11099-07-3

GLYCERYL POLYACRYLATE Glyceryl Polyacrylate What Is Glyceryl Polyacrylate? The glyceryl monoesters (Glyceryl Laurate, Glyceryl Laurate SE, Glyceryl Laurate/Oleate, Glyceryl Adipate, Glyceryl Alginate, Glyceryl Arachidate, Glyceryl Behenate, Glyceryl Caprate, Glyceryl Caprylate, Glyceryl Caprylate/Caprate, Glyceryl Citrate/Lactate/Linoleate/Oleate, Glyceryl Cocoate, Glyceryl Collagenate, Glyceryl Erucate, Glyceryl Hydrogenated Rosinate, Glyceryl Hydrogenated Soyate, Glyceryl Hydroxystearate, Glyceryl Isopalmitate, Glyceryl Isostearate, Glyceryl Isostearate/Myristate, Glyceryl Isostearates, Glyceryl Lanolate, Glyceryl Linoleate, Glyceryl Linolenate, Glyceryl Montanate, Glyceryl Myristate, Glyceryl Isotridecanoate/Stearate/Adipate, Glyceryl Oleate SE, Glyceryl Oleate/Elaidate, Glyceryl Palmitate, Glyceryl Palmitate/Stearate, Glyceryl Palmitoleate, Gyceryl Pentadecanoate, Glyceryl Polyacrylate, Glyceryl Rosinate, Glyceryl Sesquioleate, Glyceryl/Sorbitol Oleate/Hydroxystearate, Glyceryl Stearate/Acetate, Glyceryl Stearate/Maleate, Glyceryl Tallowate, Glyceryl Thiopropionate, Glyceryl Undecylenate) occur primarily as white to yellow oils or oily waxes. Ingredient names containing a "/", such as Glyceryl Caprylate/Caprate, are mixtures of monoesters, Glyceryl Caprylate and Glyceryl Caprate. SE in the name means that it is a self-emulsifying grade that contains some sodium and/or potassium salts of the acid. Glyceryl monoesters are primarily used in the formulation of creams and lotions, moisturizers, and other skin care products, but glyceryl monoesters can also be found in permanent waves, deodorants, bath soaps, eye makeup and foundations. Why is it used in cosmetics and personal care products? The following functions have been reported for the glyceryl monoesters. Film former - Glyceryl Polyacrylate Hair conditioning agent - Glyceryl Collagenate, Glyceryl Lanolate Hair waving and straightening agent - Glyceryl Thiopropionate Reducing agent - Glyceryl Thiopropionate Skin-conditioning agent - emollient - Glyceryl Laurate, Glyceryl Laurate/Oleate, Glyceryl Adipate, Glyceryl Alginate, Glyceryl Arachidate, Glyceryl Arachidonate, Glyceryl Behenate, Glyceryl Caprate, Glyceryl Caprylate, Glyceryl Caprylate/Caprate, Glyceryl Citrate/Lactate/Linoleate/Oleate, Glyceryl Cocoate, Glyceryl Collagenate, Glyceryl Erucate, Glyceryl Hydrogenated Rosinate, Glyceryl Hydrogenated Soyate, Glyceryl Hydroxystearate, Glyceryl Isopalmitate, Glyceryl Isostearate. Glyceryl Isostearate/Myristate, Glyceryl Isostearates, Glyceryl Lanolate, Glyceryl Linoleate, Glyceryl Linolenate, Glyceryl Montanate, Glyceryl Myristate, Glyceryl Isotridecanoate/Stearate/Adipate, Glyceryl Oleate/Elaidate, Glyceryl Palmitate, Glyceryl Palmitate/Stearate, Glyceryl Palmitoleate, Glyceryl Rosinate, Glyceryl Sesquioleate, Glyceryl/Sorbitol Oleate/Hydroxystearate, Glyceryl Stearate/Acetate, Glyceryl Stearate/Malate, Glyceryl Tallowate, Glyceryl Undecylenate Skin-conditioning agent - miscellaneous - Glyceryl Collagenate Surfactant - emulsifying agent - Glyceryl Laurate, Glyceryl Laurate SE, Glyceryl Laurate/Oleate, Glyceryl Arachidate, Glyceryl Behenate, Glyceryl Caprate, Glyceryl Caprylate, Glyceryl Caprylate/Caprate, Glyceryl Cocoate, Glyceryl Erucate, Glyceryl Hydrogenated Rosinate, Glyceryl Hydroxystearate, Glyceryl Isopalmitate, Glyceryl Isostearate, Glyceryl Isostearate/Myristate, Glyceryl Isostearates, Glyceryl Lanolate, Glyceryl Linoleate, Glyceryl Linolenate, Glyceryl Montanate, Glyceryl Myristate, Glyceryl Isotridecanoate/Stearate/Adipate, Glyceryl Oleate SE, Glyceryl Oleate/Elaidate, Glyceryl Palmitate, Glyceryl Palmitate/Stearate, Glyceryl Palmitoleate, Glyceryl Pentadecanoate, Glyceryl Rosinate, Glyceryl/Sorbitol Oleate/Hydroxystearate, Glyceryl Stearate/Malate, Glyceryl Tallowate, Glyceryl Undecylenate Viscosity increasing agent - aqueous - Glyceryl Alginate Viscosity increasing agent - nonaqueous - Glyceryl Arachidate Scientific Facts: The glyceryl monoesters, or monoglycerides, are all prepared from glycerin. Most are also prepared from fatty acids or fatty acid derivatives. Some of these fatty acids may come from refined vegetable oils For example, Glyceryl Linolenate is produced from glycerin and linoleic acid, which can be made from sunflower oil. Glyceryl Polyacrylate is the ester of glycerin and polyacrylic acid. GLYCERYL POLYACRYLATE GLYCERYL POLYACRYLATE is classified as : Film forming COSING REF No: 76245 Chem/IUPAC Name: 2-Propenoic acid, homopolymer, esters with 1,2,3-propanetriol GLYCERYL POLYACRYLATE N° CAS : 104365-75-5 "Pas terrible" dans toutes les catégories. Nom INCI : GLYCERYL POLYACRYLATE Classification : Polymère de synthèse Ses fonctions (INCI) Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles Cet ingrédient est présent dans 0.18% des cosmétiques. Crème visage (1,09%) Details Glyceryl acrylate/acrylic acid copolymer is the fancy word for a common polymer (big molecule from repeated subunits), namely polyacrylic acid (aka carbomer when it comes to cosmetics) with glycerin attached to it in some places. The main thing of this polymer is that it forms a hydrogel (trade named Lubrajel) that can sit on top of the skin and provide moisturizing, water-soluble ingredients such as glycerin to the skin. Think of it as a very thin, wet sponge that a cosmetic manufacturer can fill with good ingredients for your skin. It also works as a thickening agent (remember, it is a carbomer type of molecule), and can provide the skin with a nice slippery feel. It can also draw water to the skin, providing skin hydration. Glyceryl polyacrylate Glyceryl polyacrylate is a chemical compound derived from glycerin. It is used in cosmetics and personal care products as an ingredient that dries to form a thin coating on the skin 1. According to the Cosmetic Ingredients Review (an independent committee established by the Personal Care Products Council, an industry trade association that thoroughly reviews and assesses the safety of ingredients used in cosmetics), glyceryl polyacrylate is safe to use in the amounts present in our products 2. GLYCERYL POLYACRYLATE The synthetically produced glyceryl polyacrylate is an ester of glycerin and polyacrylic acid and is used in cosmetic products as a film former, among other things. The substance forms a fine film that prevents epidermal water loss. Hyaluronic acid and valuable active ingredients thus remain longer in the skin and can develop their effect even better.

GLYCERYL RICINOLEATE 30 EO (Gliseril Risinoleat 30 EO, Glyceryl Ricinoleate 30 eo) What Is Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO)? Ricinus Communis (Castor) Seed Oil is a vegetable oil obtained from the seeds of the Ricinus communis plant. A number of ingredients made from Castor Oil may also be used in cosmetic products. These ingredients include Cetyl Rinoleate, Ethyl Ricinoleate, Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO), Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) SE (SE stands for self-emulsifying, which means it contains a small amount of sodium or potassium stearate), Glycol Ricinoleate, Hydrogenated Castor Oil, Isopropyl Ricinoleate, Methyl Ricinoleate, Octyldodecyl Ricinoleate, Potassium Ricinoleate, Ricinoleic Acid, Sodium Ricinoleate and Zinc Ricinoleate. In cosmetics and personal care products, Castor Oil and related ingredients are used in the formulation of many different cosmetic and personal care products including lipstick, skin-care products, and bath soaps. Why is Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) used in cosmetics and personal care products? The following functions have been reported for these ingredients. Anticaking agent - Zinc Ricinoleate Deodorant agent - Zinc Ricinoleate Emulsion stabilizer - Glycol Ricinoleate Opacifying agent - Zinc Ricinoleate Skin conditioning agent - emollient - Ethyl Ricinoleate, Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO), Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) SE, Glycol Ricinoleate, Isopropyl Ricinoleate, Methyl Ricinoleate Skin conditioning agent - occlusive - Ricinus Communis (Castor) Seed Oil; Cetyl Ricinoleate, Hydrogenated Castor Oil, Octyldodecyl Ricinoleate Surfactant - cleansing agent - Potassium Ricinoleate, Sodium Ricinoleate, Ricinoleic Acid Surfactant - emulsifying agent - Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO), Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) SE, Potassium Ricinoleate, Sodium Ricinoleate Viscosity increasing agent - nonaqueous - Hydrogenated Castor Oil Safety Information: The Food and Drug Administration includes Castor Oil on its list of natural flavoring substance and on its list of multipurpose direct food additives. Castor Oil is also classified by the FDA as safe and effective as a stimulant laxative. The safety of Ricinus Communis (Castor) Seed Oil, Cetyl Rinoleate, Ethyl Ricinoleate, Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO), Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) SE, Glycol Ricinoleate, Hydrogenated Castor Oil, Isopropyl Ricinoleate, Methyl Ricinoleate, Octyldodecyl Ricinoleate, Potassium Ricinoleate, Ricinoleic Acid, Sodium Ricinoleate and Zinc Ricinoleatehave been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated the scientific data and noted the overall pattern of use of these ingredients in different product categories. The CIR Expert Panel concluded that Castor Oil and its derivatives were safe for use as cosmetic ingredients. More safety Information: CIR Safety Review: The CIR Expert Panel considered that the available data on Ricinus Communis (Castor) Seed Oil, Hydrogenated Castor Oil, Ricinoleic Acid, and salts and esters of Ricinoleic Acid were sufficient for evaluating the safety of these ingredients. Because Ricinus Communis (Castor) Seed Oil contains Ricinoleic Acid as the primary fatty acid group, safety test data on the oil was considered broadly applicable to this entire group of cosmetic ingredients. Overall, the available data demonstrated few toxic effects in acute, subchronic, or chronic toxicity tests. Additionally, there were no genotoxic effects of Castor Oil in in vitro or in vivo tests. UV absorption spectra on Ricinus Communis (Castor) Seed Oil and Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) indicated maximum absorbance at 270 nm, suggesting there would be no photosensitization potential of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) or Ricinus Communis (Castor) Seed Oil in human subjects exposed to the sun. Reactions classified as either significantly irritating or allergic were not observed in studies on Ethyl Ricinoleate, and the CIR Expert Panel concluded that the Castor Oil derivatives were not sensitizers. The CIR Expert Panel also determined that these ingredients may be used safely in aerosolized products because packaging and use ensure that particulates are not respirable. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is also known as 9-Octadecenoic acid,12-hydroxy-,(9Z,12R)-,monoester with 1,2,3-propanetriol. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is a chemical product which appears under the form of a yellow liquid, is dispersible in water, is soluble in most organic solvents, is combustible. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) used as a low-temperature lubricant, a non-drying emulsifying agent, a solvent, a plasticizer, in cosmetics, in the processing of leather, paper and textile, and for the stabilizing of latex paints against breakdown due to repeated freeze-thaws. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) used as antifoaming agent, softening agent, antistatic agent, dispersing, agent, degreasing agent, plasticizing agent, thickening agent and chemical intermediate in the industry. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is ester of fatty acid & derivative of castor oil. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can be used as emollient, emulsifier, personal care ingredient & lubricant. This Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is widely demanded in the international market due to its high effectively, eco-friendliness and purity, and is offered in different grades to meet the varied needs of our clients. Moreover, we are offering the entire range at an affordable cost to our clients. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) In cosmetic formulations Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can have the following functions: Emulsifier/co-emulsifier, refatting agent, dispersing aid. But the primary function of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is a skin protection agent. The availability of the free hydroxyl groups of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is the reason for its excellent skin protection. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is surface-active because of its free hydroxyl groups of mono- and diglycerides. It forms W/O-emulsions and also acts as co-emulsifier in O/W-emulsions. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is well-tolerated by the skin and mucosa. Skin reactivity to aggressive substances is decreased and therefore Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can be readily used as a skin-protecting agent. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is attracted to the adsorption sites on the skin surface, and therefore protects it from being attacked by harmful substances. Characteristics of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) The consistency of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can be liquid to pasty, due to temperature conditions fractionated crystallization can occur. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is miscible with fats and oils. It is readily soluble in ethanol, diethylether, toluole and methylene chloride. It is water dispersible. Polar binding forces (Van-der-Waals forces) come from the glyceryl hydroxyl groups and from the 12-hydroxy-9-cis-octadecanoic acid (ricinoleic acid). Because of its purely vegetable origin and manufacturing process, Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is free from heavy metals, catalyst residues and solvents. It is stabilized with BHT. It contains max. 0.5 % of water. How to use Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is used in nearly all skin care preparations such as creams, lotions, bath oils, shaving formulations, refatting soap and shower agents in amounts of 2 – 10%. In an epicutaneous test and after long use in cosmetic preparations, no irritations were observed. Ricinus Communis (Castor) Seed Oil is a vegetable oil obtained from the seeds of the Ricinus communis plant. A number of ingredients made from Castor Oil may also be used in cosmetic products. These ingredients include Cetyl Rinoleate, Ethyl Ricinoleate, Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO), Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) SE (SE stands for self-emulsifying, which means it contains a small amount of sodium or potassium stearate), Glycol Ricinoleate, Hydrogenated Castor Oil, Isopropyl Ricinoleate, Methyl Ricinoleate, Octyldodecyl Ricinoleate, Potassium Ricinoleate, Ricinoleic Acid, Sodium Ricinoleate and Zinc Ricinoleate. In cosmetics and personal care products, Castor Oil and related ingredients are used in the formulation of many different cosmetic and personal care products including lipstick, skin-care products, and bath soaps. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is the monoester of glycerol and ricinoleic acid. Castor oil contains 87–90% Glycerol Ricinoleate. Ricinoleic acid is metabolized by both β-oxidation and α-oxidation. Acute oral toxicity tests in mice indicated that Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) has an LD50 greater than 25.0 ml/kg and is, at most, mildly irritating to unrinsed rabbit eyes. This ingredient was not a primary skin irritant. Castor oil was nonmutagenic by the Ames test. Ricinoleic acid was not a carcinogen when tested in mice. In human single-insult occlusive patch tests, no indication of skin irritation potential was observed in the two products containing 5.6% Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO). The available data on Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) were insufficient to determine whether this ingredient, under each relevant condition of use, was either safe or not safe. The types of data required before a decision can be made include: (1) 28 day chronic dermal toxicity in guinea pigs, and (2) clinical sensitization and photosensitization studies (or an appropriate ultraviolet spectrum instead of the photosensitization data). In the current application authorisation is sought under article 10(2) for Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (E 484) under the category/functional group 1(c) "technological additives"/"emulsifiers" according to Annex I of Regulation (EC) No 1831/2003. The authorisation is sought for the use of the feed additive for all animal species and categories. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (E 484) or polyethylene glycol (PEG X) castor oil is obtained by mixing X moles (X from 6.5 to 200) of ethylene oxide to one mole of castor oil. The major components formed are the tri-ricinoleate esters of ethoxylated glycerol. The Applicant suggested the following technical specification ranges to characterise the feed additive: 16 to 162 mg KOH/g for the saponification value; 5.5 to 7.5 for pH; 0 to 2 mg KOH/g for the acid value and 0 to 3% wt for the water content. The feed additive is intended to be incorporated directly into feedingstuffs or through premixtures, with no recommended minimum or maximum concentration levels. However, typical inclusion levels range from 10 to 20 g E 484 /kg feedingstuffs. For the identification of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (PEG X (X = 6.5-200) castor oil) in the feed additive the Applicant proposed several official methods developed by the American Oil Chemists' Society (AOCS) and the standard of American Society for Testing and Materials (ASTM) for the determination of the: - saponification value (AOCS Cd 3-25); - acid value (AOCS 3d-63); - pH value (ASTM Standard D1172-95:2007) and - water content (AOCS Ca 2e-84). Even though no performance characteristics are provided, the EURL recommends for official control the official AOCS methods and the ASTM standard to identify Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (PEG X castor oil) in the feed additive. The accurate quantification of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) in premixtures and feedingstuffs is not achievable experimentally. Nevertheless, the Applicant presented qualitative data for the identification of the active substance in premixtures and feedingstuffs using Nuclear Magnetic Resonance (NMR). This data does not allow any recommendation by the EURL for official control to quantify Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) in premixtures and feedingstuffs. In the current application authorisation is sought under article 10(2) (re-evaluation of the already authorised additives under provisions of Council Directive 70/524/EEC) for Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (E 484) under the category/functional group 1(c) "technological additives"/"emulsifiers" according to Annex I of Regulation (EC) No 1831/2003 [1]. The authorisation is sought for the use of the feed additive for all animal species and categories [2]. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (E 484) or "polyethylene glycol (PEG X) castor oil" is obtained by mixing X moles (X from 6.5 to 200) of ethylene oxide to one mole of castor oil under controlled conditions. The major components formed are the tri-ricinoleate esters of ethoxylated glycerol with minor amounts of polyoxyethylene ricinoleates, ethoxylated glycerols and polyethylene glycols [3]. Castor oil itself is a triglyceride extracted from the seeds of the plant Ricinus communis and comprising mainly ricinoleic acid (>85 %) with minor amounts of palmitic, oleic, linoleic, linolenic, dihydroxystearic and arachidic acids. For the identification of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (PEG X (X = 6.5-200) castor oil) in the feed additive the Applicant proposed several official methods developed by the American Oil Chemists' Society (AOCS) and the standard of American Society for Testing and Materials (ASTM) for the determination of the saponification- [6], acid- [7], pH- [8] values, and water content [9]. In addition, the EURL identified equivalent generic methods described in the internationally recognised FAO JECFA monograph for food additives [10] and/or in the European Pharmacopoeia monographs [11-15]. Even though no performance characteristics are provided, the EURL recommends for official control the AOCS methods and the ASTM standard to identify Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (PEG X castor oil) in the feed additive. However, the methods described in the FAO JECFA and the European Pharmacopoeia monographs mentioned above can be considered for the identification of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) (PEG X castor oil) in the feed additive. The accurate quantification of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) in premixtures and feedingstuffs is not achievable experimentally. Nevertheless, the Applicant presented qualitative data for the identification of the active substance in premixtures and feedingstuffs using Nuclear Magnetic Resonance (NMR) [16]. This data shows that the active substance can be identified unambiguously in premixtures [17], while a matrix effect is observed when investigating feedingstuffs samples [16]. Hence, the data provided does not allow any recommendation by the EURL for official control to quantify Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) in premixtures and feedingstuffs. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is a monoester of glycerin and ricinoleic acid. In cosmetic formulations Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can have the following functions: emulsifier/co-emulsifier, refatting agent, dispersing aid. But the primary function of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is a skin protection agent. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is used in nearly all skin care preparations such as creams, lotions, bath oils, shaving formulations, refatting soap and shower agents in amounts of 2 – 10%. In an epicutaneous test and after long use in cosmetic preparations, no irritations were observed. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is the chief constituent of castor oil and is the triglyceride of ricinoleic acid.[1] Castor oil, the expressed natural fatty oil of the seeds of Ricinus communis also contains mixtures of the glycerides of isoricinoleic acids and much smaller traces of tristearin and the glyceride of dihydroxysteric acid. Ricinolein is the active principle in the use of castor oil as a purgative and solvent for several medically useful alkaloids. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is also known as 9-Octadecenoic acid,12-hydroxy-,(9Z,12R)-,monoester with 1,2,3-propanetriol. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is a chemical product which appears under the form of a yellow liquid, is dispersible in water, is soluble in most organic solvents, is combustible. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) used as a low-temperature lubricant, a non-drying emulsifying agent, a solvent, a plasticizer, in cosmetics, in the processing of leather, paper and textile, and for the stabilizing of latex paints against breakdown due to repeated freeze-thaws. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) used as antifoaming agent, softening agent, antistatic agent, dispersing, agent, degreasing agent, plasticizing agent, thickening agent and chemical intermediate in the industry. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is ester of fatty acid & derivative of castor oil. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can be used as emollient, emulsifier, personal care ingredient & lubricant. This Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is widely demanded in the international market due to its high effectively, eco-friendliness and purity, and is offered in different grades to meet the varied needs of our clients. Moreover, we are offering the entire range at an affordable cost to our clients. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) In cosmetic formulations Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can have the following functions: Emulsifier/co-emulsifier, refatting agent, dispersing aid. But the primary function of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is a skin protection agent. The availability of the free hydroxyl groups of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is the reason for its excellent skin protection. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is surface-active because of its free hydroxyl groups of mono- and diglycerides. It forms W/O-emulsions and also acts as co-emulsifier in O/W-emulsions. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is well-tolerated by the skin and mucosa. Skin reactivity to aggressive substances is decreased and therefore Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can be readily used as a skin-protecting agent. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is attracted to the adsorption sites on the skin surface, and therefore protects it from being attacked by harmful substances. Characteristics of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) The consistency of Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) can be liquid to pasty, due to temperature conditions fractionated crystallization can occur. Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is miscible with fats and oils. It is readily soluble in ethanol, diethylether, toluole and methylene chloride. It is water dispersible. Polar binding forces (Van-der-Waals forces) come from the glyceryl hydroxyl groups and from the 12-hydroxy-9-cis-octadecanoic acid (ricinoleic acid). Because of its purely vegetable origin and manufacturing process, Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is free from heavy metals, catalyst residues and solvents. It is stabilized with BHT. It contains max. 0.5 % of water. How to use Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) Glyceryl Ricinoleate 30 eo (Gliseril Risinoleat 30 EO, GLYCERYL RICINOLEATE 30 EO) is used in nearly all skin care preparations such as creams, lotions, bath oils, shaving formulations, refatting soap and shower agents in amounts of 2 – 10%. In an epicutaneous test and after long use in cosmetic preparations, no irritations were observed.

Glyceryl Rosinate is a monoester of glycerin and mixed long chain acids derived from Rosin
Glyceryl rosinate also known as, GEGR (Glyceryl ester of gum rosin)/ ester gum is a monoester of glycerol and mixed long-chain acids of rosin, also called rosin acid/resin acid.


CAS Number: 65997-13-9 / 8050-31-5
EC Number: 266-042-9 / 232-482-5
Chem/IUPAC Name: Resin acids and Rosin acids, esters with glycerol
Molecular Formula: C63H62O3


Glyceryl rosinate also known as, GEGR (Glyceryl ester of gum rosin)/ ester gum is a monoester of glycerol and mixed long-chain acids of rosin, also called rosin acid/resin acid.
Glyceryl rosinate is produced via a special process; the process provides product stability plus it does not lose its quality upon aging.


There are various raw material sources available in the market, and those are ruby red to black thermoplastic resin, obtained from pinewood.
Glyceryl rosinate is an ester of long chain acids derived from a plant-based ingredient known as rosin.
Glyceryl rosinate may be plant-derived or synthetic, with both types working as emollients, surfactants, and emulsifiers.


Glyceryl rosinate is a pale yellow to amber solid with a sweet taste that is used in citrus flavored soft drinks, chewing gum, and ice cream.
Glyceryl rosinate is an ester of rosin and glycerol.
Glyceryl Rosinate, also called Glycerol Ester of Gum Rosin (GEGR) or Ester Gum, is anoil-soluble food additive.


Its high density helps keep oils in suspension in water and this property is the reason why Glyceryl rosinate is often used as a beverage stabilizer.
Glyceryl rosinate, also called Glycerol Ester of Hydrogenated Rosin (GEHR) and Ester Of Hydrogenated Rosin, is esterified from refined hydrogenated rosin and edible glycerol.


Glyceryl rosinate, also called Glycerol Ester of Gum Rosin (GEGR) or Ester Gum, is anoil-soluble food additive.
Glyceryl Rosinate is the important material for adhesive and food additive.
When producing, crushed the rosin into small pieces and add Glyceryl rosinate to the reactor, start heating, glycerol ester and zinc oxide all the time to join the reactor.


If Glyceryl rosinate is not melted, stop the stirring.
If Glyceryl rosinate melts, continue to stir and continue to warm up to 270°C in 30 minutes, and then in 2h slowly to 290 & lt; 0 & gt; C.
1h before this phase is for the esterification reaction stage, 1h after the reaction gradually slowed down, when reaching 290 ℃, continue to heat up, while opening the valve to steam the excess water and glycerol, volatile matter.


And then 0.5h rise to 305 ℃, sampling inspection, acid value below 20, the softening point above 80 ℃, light color and transparent glyceryl rosinate are required.
Glyceryl rosinate also named Ester Gum, it's made of gum rosin and glycerol ester with stabilizing treatment.


Glyceryl rosinate can be perfectly dissolved in polymers.
Glyceryl rosinate is a solid.
Glyceryl rosinate is insoluble in water.
Glyceryl rosinate is stable.


Glyceryl rosinate is under strong acid or strong alkali condition, easily hydrolyzed.
Glyceryl rosinate contains glycerol as alcohol component in esters or condensed with other (poly) alcohols or sugars.
Glyceryl rosinate is salts or esters of resin acid.
Glyceryl rosinate is an ester of long chain acids derived from a plant-based ingredient known as rosin.



USES and APPLICATIONS of GLYCERYL ROSINATE:
Glyceryl rosinate can be used with polymers such as EVA,SBS & SIS to make industrial grade hot melt adhesive,
acrylic adhesive etc.
Glyceryl rosinate is used solvent base adhesive for SBR rubber, natural rubber and acrylic.


Glyceryl rosinate can be polymerized with plant oil for phenolic paint, and improve the hardness and brightness.
Glyceryl rosinate can be used as tackifier and binder for road marking paint.
Glyceryl rosinate is widely used as a base in the production of chewing-gum.


Glyceryl rosinate also serves as analternative to brominated vegetable oil in citrus oil flavored soft drinks.
In some cases both ingredients are used together.
Glyceryl rosinate is used Performance claims, Sustainability claims, Function, Applications, Usage level


Glyceryl rosinate is used Chemical group, Chemical properties, Physical properties, Appearance, Colors, Origin, Origin Species.
Glyceryl rosinate's high density helps keep oils in suspension in water and this property is the reason why it is often used as a beverage stabilizer.
Glyceryl rosinate is a kind of super light color tackifying rosin resin, which is esterified from refined hydrogenated rosin and edible glycerol, and through series combined technologies units of catalytic hydrogenation.


With benefit of light color, low odor, good heat stability and excellent ageing resistance, Glyceryl rosinate is mainly used in screen protection film, medicinal patch, diaper adhesive, PSA and HMA.
Glyceryl rosinate is used as anti-oxidant and softening with good tase in the production of SBR or polyvinyl acetate based chewing-gum and bubble gum.


Glyceryl rosinate is used as emulsification stabilizer in soft drink
Glyceryl rosinate is used as tackifier in depilatory and Cosmetic industry
Glyceryl rosinate is applied on coated urea fertilizer for tobacco


Glyceryl rosinate is used as a thixotropic agent of pesticide dispersion
Glyceryl rosinate comes with excellent adhesivity to be widely used in various adhesive manufactures, it is light color and economic type of tackifier material.


Glyceryl rosinate is used as lubricant.
Glyceryl rosinate is used as dispersing agent, emulsion stabilizer.
Glyceryl rosinate is used as adhesive.


Glyceryl rosinate is used Film-forming agent, perfume in personal care products.
Glyceryl rosinate is used as food additive (depilatory, perfume).
Amounts of Glyceryl rosinate in use range from 8% in mascaras, 1–10% in lipsticks to upwards of 96% in depilatories, attesting to the versatility Glyceryl rosinate has.


Attesting to its safety, Glyceryl rosinate is also used in beverages to create texture and improve flavor stability.
Its high density allows Glyceryl rosinate to keep oils suspended in water.
Therefore, Glyceryl rosinate is often used as a stabilizer in beverages and is quite common in chewing gum.


In cosmetics, Glyceryl rosinate is primarily used in wax for hair removal, mascaras, and lipsticks.
Glyceryl rosinate is permitted in organic/bio products.
Glyceryl rosinate is widely used as a base in the production of chewing-gum.


Glyceryl rosinate also serves as analternative to brominated vegetable oil in citrus oil flavored soft drinks.
In some cases both ingredients are used together.
Glyceryl rosinate is most often used when oils need to remain suspended in a water-based solution.


For this reason, Glyceryl rosinate tends to be used in blends that include plant oils such as castor seed or olive and emollient shea butter.
Such blends are sometimes used as replacements for the animal-derived emollient lanolin.
Glyceryl rosinate can be used with polymers such as EVA、SBS & SIS to make industrial grade hot melt adhesive, acrylic adhesive etc.


Glyceryl rosinate is used Solvent base adhesive for SBR rubber, natural rubber and acrylic.
Glyceryl rosinate can be polymerized with plant oil for phenolic paint, and improve the hardness and brightness.
Glyceryl rosinate can be used as tackifier and binder for road marking paint.


Glyceryl rosinate is a monoester of glycerol and long-chain mixed rosin acids (rosinic acid).
Glyceryl rosinate is produced by a special process that provides stability to the product and maintains its longer shelf life.
Glyceryl rosinate can have a synthetic or natural form.


The natural form may contain traces of resins that are capable of causing an allergic reaction, the synthetic form should be safe to use.
Glyceryl rosinate is used as a food (beverage stabilizer, emulsifier, chewing gum) and cosmetic additive.
In general, Glyceryl rosinate is an emulsifier (combines the water and oil phases), an emollient, a surfactant (forms foam) and a skin conditioner.


When applied locally to the skin, Glyceryl rosinate creates an occlusive and protective film on its surface that prevents the loss of moisture from the surface of the skin.
Glyceryl rosinate is added to personal care products ,depilatory creams and in various cosmetic products (mascaras, lipsticks, ...).


Glyceryl rosinate’s made of gum rosin and glycerol ester with stabilizing treatment.
Glyceryl rosinate can be perfectly dissolved in polymers.
Glyceryl Rosinate comes with excellent adhesivity to be widely used in various adhesive manufactures, it is light color and economic type of tackifier material.


Glyceryl rosinate is a Glycerol Ester of Gum Rosin, Ester Gum, GEGR. The Industry grade of Glyceryl Rosinate (a polyol ester of rosin), also called Glycerol Ester of Gum Rosin (GEGR), which is used for specialty industries of adhesives,coating and paints.
Glyceryl rosinate is also widely used in polymers including EVA, acrylics, polyurethanes, SIS and SBS.


This ester of long chain acids is naturally obtained from a plant ingredient called rosin.
In cosmetics Glyceryl rosinate is used as a skin-conditioner, emulsifier, and surfactant.
Glyceryl rosinate acts as a stabilizer and moisturizing agent.


Glyceryl rosinate is a triglyceride of vegetable origin combined with rosin glycerol ester and olive oil unsaponifiables.
Moreover, Glyceryl rosinate is an alternative to lanolin and stabilizes emulsion systems.
Glyceryl rosinate provides water retention and hydration properties.


Glyceryl rosinate is used in personal care and cosmetic applications.
Glyceryl rosinate is used Skin care (Facial care, Facial cleansing, Body care, Baby care); Hand creams, Lotions. Group: Raw Materials; Thickeners; Stabilizers; Moisturizing Agents.


Glyceryl Rosinate is used Fragrance Ingredient; Skin-Conditioning Agent - Emollient; Surfactant - Emulsifying Agent; FILM FORMING; PERFUMING.
Glyceryl Rosinate Also Known As Glycerol Ester Of Rosin, is made of gum rosin mixed with glycerol ester and heat them up, under pressure from superposition.
Glyceryl rosinate was heated to 200 ° C. Add 10 ~ 15% glycerol, heating to 230-285 ℃, to maintain 5 - lOh, reaction to prevent oxidation, should be filled with CO2 gas, stop heating, vacuum pump and gas for about 30min, then natural cooling.


The reaction can be used calcium oxide, zinc oxide as a catalyst.
Glyceryl Rosinate rosin esters can be used for food emulsifier, in the pharmaceutical agent for sustained release matrix material, ointment base, emulsifiers, adhesives, pressure-sensitive adhesive for the slow release tablets, patch, emulsion And the like.


Glyceryl rosinate is used in the food industry for gum, chewing gum and other gum base.
The amount of discretion, the general amount of 0.1 to 5%.
Glyceryl rosinate is a naturally originating ester of rosin and glycerol.


Glyceryl rosinate's high density makes it possible to keep the oils in suspension in the water.
Glyceryl rosinate is often used as a stabilizer in drinks, it is often found in chewing gum.
In cosmetics, Glyceryl rosinate is mainly used in depilatory waxes, mascaras and lipsticks.


Glyceryl rosinate is an ester of long chain acids derived from a plant-based ingredient known as rosin.
Glyceryl rosinate functions as a skin-conditioning agent, surfactant, and emulsifier and has been found safe as used in cosmetics.



USE AND BENEFITS OF GLYCERYL ROSINATE:
Similar to other monoesters, they have a structure that fits for use as an emulsifier or surfactant.
An emulsifier holds both the oil and water phase together efficiently.
They have certain active functional groups in a molecular structure that takes care of the water part and long aliphatic chain, in the same structure of a molecule that takes care of the oil part.

So, the emulsifier helps the formulation look uniform and appealing to the eye.
Surfactant is another use of the ester gum, which helps create foam upon actual use of a product.
Although foam may not be necessary for the product it is very important for the consumer as foam is normally seen as a way of showing that it is actually cleaning.

The Esters usually imparts moisturization and are good film formers. They form an occlusive and protective film that helps skin retain moisture. It is helpful when dry skin is a real problem.
Glyceryl rosinate is used in personal care products, depilatory or hair removal creams, and in various cosmetic products.



HOW GLYCERYL ROSINATE IS CLASSIFIED:
*Emulsifiers
*Emollients
*Cleansing Agents



BENEFITS OF GLYCERYL ROSINATE:
Glyceryl rosinate's high density helps keep oils in suspension in water and this property is why it is often used as a beverage stabilizer.
Glyceryl rosinate also serves as an alternative to brominated vegetable oil in citrus oil-flavored soft drinks.
Glyceryl rosinate is totally soluble in aromatic, aliphatic and chlorinated solvents, Not soluble in alcohols, ketones (except butanol and MEK)



FEATURES OF GLYCERYL ROSINATE:
*Glyceryl rosinate can be dissolved in many solvent such as petroleum hydrocarbons, aromatics, ester, ketone, gasoline, benzene, acetic ether, acetone, turpentine and so on.
*Glyceryl rosinate cannot be dissolved in water and alcohol.
*Glyceryl rosinate is With light color, low-odor, anti-oxidization, thermal stability, strong adhesivity and other features.
*Glyceryl rosinate can be widely used with many polymers such as NR, CR, SBR, EVA, SIS, SBS etc.



GLYCERYL ROSINATE AT A GLANCE:
*Versatile ingredient found in skin care, makeup, and beverages
*Works as an emollient, emulsifier, and surfactant
*Often combined with plant oils and delicate emollients to improve stability
*Very high amounts are used in depilatories



FUNCTIONS OF GLYCERYL ROSINATE:
*Film forming :
Glyceryl rosinate produces a continuous film on skin, hair or nails
*Perfuming :
Glyceryl rosinate is used for perfume and aromatic raw materials



WHAT DOES GLYCERYL ROSINATE DO IN A FORMULATION?
*Film forming
*Perfuming



FEATURES OF GLYCERYL ROSINATE:
» Also named Glyceryl Rosinate or Ester Gum.
» Glyceryl rosinate can be dissolved in many solvent such as petroleum hydrocarbons, aromatics, ester, ketone, gasoline, benzene, acetic ether, acetone, turpentine and so on.
» Glyceryl rosinate cannot be dissolved in water and alcohol.
» Glyceryl rosinate comes with light color, low-odor, anti-oxidization, thermal stability, strong adhesivity and other features.
» Glyceryl Rosinate can be widely used with many polymers such as NR, CR, SBR, EVA, SIS, SBS etc.



FUNCTIONS OF GLYCERYL ROSINATE IN COSMETIC PRODUCTS:
*FILM FORMING
Glyceryl rosinate produces a continuous film on skin, hair and / or nails
*PERFUMING
Part of perfume oils and / or flavours



PHYSICAL and CHEMICAL PROPERTIES of GLYCERYL ROSINATE:
Color (Fe-Co Scale): 3-5
Softening point (R&B, °C): 85-95
Acid number (mgKOH/g) max: 9
Solubility (with toluene 1:1): clear



FIRST AID MEASURES of GLYCERYL ROSINATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of GLYCERYL ROSINATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of GLYCERYL ROSINATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of GLYCERYL ROSINATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of GLYCERYL ROSINATE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of GLYCERYL ROSINATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Resin acids and Rosin acids, esters with glycerol
Butyrospermum Parkii Butter, Glyceryl Rosinate, Olea Europaea Oil Unsaponifiables.
8050-31-5
GLYCEROL ESTER OF ROSIN (RIFM)
GLYCERYL MONOROSINATE
GLYCERYL ROSINATE [INCI]
RESIESTER GUM A 35
RESIN ACIDS AND ROSIN ACIDS, ESTERS WITH GLYCERIN
ESTERS WITH GLYCERIN RESIN ACIDS AND ROSIN ACIDS
GLYCERYL MONOROSINATE
GLYCERYL ROSINATE, RESIN ACIDS AND ROSIN ACIDS, ESTERS WITH GLYCERIN, and ROSIN GLYCEROL ESTER

GLYCERYL STEARATE Glyceryl Stearate What Is Glyceryl Stearate? Glyceryl Stearate and Glyceryl Stearate SE are esterification products of glycerin and stearic acid. Glyceryl Stearate is a white or cream-colored wax-like solid. Glyceryl Stearate SE is a "Self-Emulsifying" form of Glyceryl Stearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glyceryl Stearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is Glyceryl Stearate used in cosmetics and personal care products? Glyceryl Stearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glyceryl Stearate, and Glyceryl Stearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Scientific Facts: Glyceryl Stearate is made by reacting glycerin with stearic acid, a fatty acid obtained from animal and vegetable fats and oils. Glyceryl Stearate SE is produced by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide yielding a product that contains Glyceryl Stearate as well as potassium stearate and/or sodium stearate. What Is Glyceryl Stearate Glyceryl Stearate is esterification products of glycerin and stearic acid. Glyceryl Stearate is a white or cream-colored wax-like solid. Glyceryl Stearate SE is a "Self-Emulsifying" form of Glyceryl Stearate that also contains a small amount of sodium and or potassium stearate. In cosmetics and personal care products, Glyceryl Stearate is widely used and can be found in lotions, creams, powders, skin cleansing products, makeup bases and foundations, mascara, eye shadow, eyeliner, hair conditioners and rinses, and suntan and sunscreen products. Why is it used in cosmetics and personal care products? Glyceryl Stearate acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It also slows the loss of water from the skin by forming a barrier on the skin's surface. Glyceryl Stearate, and Glyceryl Stearate SE help to form emulsions by reducing the surface tension of the substances to be emulsified. Glyceryl Stearate is derived from palm kernel, vegetable or soy oil and is also found naturally in the human body. It acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance. It easily penetrates the skin and slows the loss of water from the skin by forming a barrier on the skin's surface. It has been shown to protect skin from free-radical damage as well. Functions of Glyceryl Stearate Glyceryl Stearate is derived from palm kernel, vegetable or soy oil and is also found naturally in the human body. It acts as a lubricant on the skin's surface, which gives the skin a soft and smooth appearance (Source). It easily penetrates the skin and slows the loss of water from the skin by forming a barrier on the skin's surface. It has been shown to protect skin from free-radical damage as well. Chemically, Glyceryl Stearate is used to stabilize products, decrease water evaporation, make products freeze-resistant, and keep them from forming surface crusts. Description: Glyceryl stearate SE (self-emulsifying as it contains a small amount 3-6% of potassium stearate) is the monoester of glycerin and stearic acid. Vegetable origin. It is an emulsifier with a HLB value of 5.8 and thus useful for making water-in-oil emulsions. It can also be used as a co-emulsifier and thickener for oil- in-water formulations. Off-white flakes, bland odor. Soluble in oil. CAS: 123-94-4 INCI Name: Glyceryl stearate Properties: Emulsifies water and oil phase, acts as stabilizer and thickener in o/w formulations, widely used in a variety of different cosmetic formulations. Use: Add to oil/emulsifier phase of formulas, melts at 55°C/130°F. Use level: 1-10%. For external use only. Applications: Moisturizing creams, lotions, ointments, antiperspirant, hair care and sunscreen. Glyceryl stearate (GMS) is one of the most commonly used ingredients in personal care formulations. But it's a material that is not well understood by most formulators. GMS (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. Glyceryl Stearate, also known as Glyceryl MonoStearate, or GMS, is EcoCert certified. Glyceryl Stearate is the natural glyceryl ester from stearic acid (glycerin and stearic acid) which offers skin conditioning, moisturization and hydration due to the glycerin component. Functions as a non-ionic opacifier, thickener, and formulation stabilizer, where it also imparts a softer, smoother, feel to your emulsions. Glyceryl Stearate is one of the best choices, for thickening and stabilizing, to use in combination with the lactylates, where it also functions as an emollient, and gives the emulsion more smoothness. SPECIFICATIONS Off White Flake / Granule Characteristic Odor Oil Soluble Store Tightly Closed, Protected from Heat 24 Month Shelf when Properly Handled, and Stored GUIDELINES Add to Oil Phase 2.0 to 5.0% Glyceryl stearate is the end result of reaction between glycerin and stearic acid. We all know what glycerin is and does (generally vegetable based humectant), and stearic acid is a fatty acid compound extracted from a variety of vegetable, animal, and oil sources such as palm kernel and soy. The end result of the reaction with glycerin and stearic acid is a cream-colored, waxy like substance. Details A super common, waxy, white, solid stuff that helps water and oil to mix together, gives body to creams and leaves the skin feeling soft and smooth. Chemically speaking, it is the attachment of a glycerin molecule to the fatty acid called stearic acid. It can be produced from most vegetable oils (in oils three fatty acid molecules are attached to glycerin instead of just one like here) in a pretty simple, "green" process that is similar to soap making. It's readily biodegradable. GLYCERYL STEARATE CAS number: 31566-31-1 - Glyceryl stearate "Good" in all categories. Origin(s): Synthetic Other languages: Estearato de glicerilo, Gliceril stearato, Glycerylstearat, Stéarate de glycérol INCI name: GLYCERYL STEARATE EINECS/ELINCS number: 250-705-4/286-490-9 Classification: Nonionic surfactant Bio-compatible (COSMOS Reference) NAMELY Glycerol stearate is used as a non-ionic emulsifier or emollient in cosmetic products. It is widely used in moisturizers and is also found in hair care products for its antistatic properties. It can be derived from palm, olive or rapeseed oil... It is authorized in bio. Its functions (INCI) Emollient : Softens and softens the skin Emulsifying : Promotes the formation of intimate mixtures between immiscible liquids by modifying the interfacial tension (water and oil) This ingredient is present in 11.81% of cosmetics. Hand cream (46.51%) Moisturizing cream box (46.15%) Anti-aging night face cream (45.88%) Anti-aging hand cream (43.75%) Mascara (42.73%) GLYCERYL STEARATE Glyceryl Stearate is the natural glyceryl ester of glycerin and stearic acid. It offers excellent hydration and moisturization. It acts as a non-ionic opacifier, thickener, emollient and formulation stabilizer. It is used in skin care and body care applications. GLYCERYL STEARATE is classified as : Emollient Emulsifying CAS Number 31566-31-1 EINECS/ELINCS No: 250-705-4 COSING REF No: 34103 INN Name: glyceryl monostearate PHARMACEUTICAL EUROPEAN NAME: glyceroli monostearas Chem/IUPAC Name: Glyceryl MonoStearate Glyceryl stearate Learn all about glyceryl stearate, including how it's made, and why Puracy uses glyceryl stearate in our products. Derived from: coconut Pronunciation: (\ˈglis-rəl\ \stē-ə-ˌrāt\) Type: Naturally-derived Other names: monostearate What Is Glyceryl stearate? Glyceryl stearate, also called glyceryl monostearate, is a white or pale yellow waxy substance derived from palm kernel, olives, or coconuts. What Does Glyceryl stearate Do in Our products? Glyceryl stearate is an emollient that keeps products blended together; it can also be a surfactant, emulsifier, and thickener in food — often it’s used as a dough conditioner and to keep things from going stale.[1] In our products, however, glyceryl stearate is used for its most common purpose — to bind moisture to the skin. For this reason, it is a common ingredient in thousands of cosmetic products, including lotions, makeup, skin cleansers, and other items.[2,3] Why Puracy Uses Glyceryl stearate We use glyceryl stearate in several of our products as a moisturizer; it also forms a barrier on the skin and prevents products from feeling greasy. As an emulsifier, it also allows products to stay blended.[5] Several studies and clinical tests find that glyceryl stearate causes little or no skin or eye irritation and is not a danger in formulations that might be inhaled.[6,7,8] In addition, a number of clinical trials have found that glyceryl stearate in moisturizers can lessen symptoms and signs of atopic dermatitis, including pruritus, erythema, fissuring, and lichenification.[9] In 1982 and again in 2015, the Cosmetic Ingredient Review deemed the ingredient safe for use in cosmetics.[10] Whole Foods has deemed the ingredient acceptable in its body care quality standards.[11] How Glyceryl stearate Is Made Glyceryl stearate is formed through a reaction of glycerin with stearic acid, which is a fatty acid that comes from animal and vegetable fats and oils. Glyceryl stearate SE, the self-emulsifying form of the substance, is made by reacting an excess of stearic acid with glycerin. The excess stearic acid is then reacted with potassium and/or sodium hydroxide. That produces a substance that contains glyceryl stearate, potassium stearate, and/or sodium stearate Glyceryl stearate (GMS) is one of the most commonly used ingredients in personal care formulations. But it’s a material that is not well understood by most formulators. GMS (EU) is normally used as a low-HLB thickening agent in lamellar gel (EU) network (LGN)-based oil-in-water emulsions, often combined with fatty alcohols. LGN-based emulsions containing thickening polymers are the most common type of oil-in-water formulations sold globally. Most GMS used in personal care products should actually be called glyceryl distearate (EU), since many common grades only contain around 40% alpha monostearate (EU), 5% glyceryl tristearate (EU), and 50% glyceryl distearate. There are also grades commercially available that contain 30%, 60%, and 90% GMS. The 90% alpha mono grades can only be produced by molecular distillation and are widely used in the food industry. Functionally, there is a big difference in performance if you use a 90% versus 40% mono. A 90% mono has a higher melting point (69°C versus 58-63°C), lighter skin feel, and a higher HLB (EU) (~4-5, versus ~3). The higher HLB of the 90% mono enables you to form LGNs much easier with lower emulsifier levels and energy than when using cetyl (EU)/stearyl alcohol (EU). There are also self-emulsifying (SE) grades of GMS available, which are typically combined with PEG 100 stearate (EU), potassium stearate (EU), or sodium lauryl sulfate (EU).

Glyceryl Stearate (Glycerol monostearate), also known as monostearin, is a mixture of variable proportions of glyceryl monostearate (C21H42O4), and glyceryl esters of fatty acids present in commercial stearic acid.
Glyceryl Stearate (Glycerol monostearate) is prepared by glycerolysis of certain fats or oils that are derived from edible sources or by esterification, with glycerin, of stearic acid that is derived from edible sources.
Glyceryl monostearate is waxy to the touch and has a slight, mild fatty odor and taste The USP describes glyceryl monostearate as consisting of not less than 90% of monoglycerides, chiefy glyceryl monostearate and glyceryl monopalmitate.

CAS: 31566-31-1
MF: C21H42O4
MW: 358.56
EINECS: 250-705-4

Glyceryl Stearate (Glycerol monostearate) Chemical Properties
Melting point: 78-81 °C
Boiling point: 410.96°C (rough estimate)
Density: 0.9700
Refractive index: 1.4400 (estimate)
Storage temp.: Sealed in dry,Store in freezer, under -20°C
Solubility: Soluble in hot ethanol, ether, chloroform, hot acetone, mineral oil, and fixed oils. Practically insoluble in water, but may be dispersed in water with the aid of a small amount of soap or other surfactant.
Form: Powder
Color: Pure-white or cream-colored, wax-like solid
Odor: faint odor
Water Solubility: Soluble in hot organic solvents.Soluble in hot water. Slightly soluble in ethanol. Insoluble in aliphatic solvents.
Merck: 14,4489
Exposure limits ACGIH: TWA 10 mg/m3; TWA 3 mg/m3
InChI: InChI=1S/C21H42O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h20,22-23H,2-19H2,1H3
InChIKey: VBICKXHEKHSIBG-UHFFFAOYSA-N
CAS DataBase Reference: 31566-31-1(CAS DataBase Reference)
EPA Substance Registry System: Glyceryl Stearate (Glycerol monostearate) (31566-31-1)

While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades:
40–55 percent monoglycerides The PhEur 6.0 describes glyceryl monostearate 40–55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols.
Glyceryl Stearate (Glycerol monostearate) contains 40–55% of monoacylglycerols, 30–45% of diacylglycerols, and 5–15% of triacylglycerols.
This PhEur grade corresponds to mono- and di-glycerides USP– NF, which has similar specifications (not less than 40% monoglycerides).

90 percent monoglycerides The USP32–NF27 describes Glyceryl Stearate (Glycerol monostearate) as consisting of not less than 90% of monoglycerides of saturated fatty acids, chiefly glyceryl monostearate (C21H42O4) and glyceryl monopalmitate (C19H38O4).
The commercial products are mixtures of variable proportions of glyceryl monostearate and glyceryl monopalmitate.
Glyceryl Stearate (Glycerol monostearate) is a white to cream-colored, wax-like solid in the form of beads, flakes, or powder.
Glyceryl Stearate (Glycerol monostearate) is waxy to the touch and has a slight fatty odor and taste.

Uses
Glyceryl Stearate (Glycerol monostearate) is an emulsifier that helps form neutral, stable emulsions.
Glyceryl Stearate (Glycerol monostearate) is also a solvent, humectant, and consistency regulator in water-in-oil and oil-in-water formulations.
In addition, Glyceryl Stearate (Glycerol monostearate) can be used as a skin lubricant and imparts a pleasant skin feel.
Glyceryl Stearate (Glycerol monostearate) is a mixture of mono-, di-, and triglycerides of palmitic and stearic acids, and is made from glycerin and stearic fatty acids.
Derived for cosmetic use from palm kernel or soy oil, Glyceryl Stearate (Glycerol monostearate) is also found in the human body.
Glyceryl Stearate (Glycerol monostearate) is very mild with a low skin-irritation profile; however, a slight risk of irritation exists if products contain poor quality glyceryl stearate.

Glyceryl Stearate (Glycerol monostearate) is also known as monostearin, is a mixture of variable proportions of glyceryl monostearate, glyceryl monopalmitate, and glyceryl esters of fatty acids present in commercial stearic acid.
Is prepared by glycerolysis of certain fats or oils that are derived from edible sources or by esterification, with glycerin, of stearic acid that is derived from edible sources.
Glyceryl Stearate (Glycerol monostearate) is a surfactant used in a variety of markets.
Glyceryl Stearate (Glycerol monostearate) is a glycerol ester made from soybean oil derived fatty acid.
Glyceryl Stearate (Glycerol monostearate) finds uses in both food and cosmetic applications.
Glyceryl Stearate (Glycerol monostearate) is a self emulsifying nonionic surfactant, used as a lubricant in confectionery, as a release agent and as a dough softener.
Glyceryl Stearate (Glycerol monostearate) is used as a low HLB emulsifier in personal care products where non animal grade products are needed.

Glyceryl Stearate (Glycerol monostearate) is widely used in cosmetics.
Glyceryl Stearate (Glycerol monostearate) is an emulsifying and solubilizing ingredient, dispersing agent, emollient, formula stabilizer, and surface-action agent.
employed in baby creams, face masks, foundation, and hand lotions, Glyceryl Stearate (Glycerol monostearate) is often derived from hydrogenated soybean oil.
Glyceryl Stearate (Glycerol monostearate) has little or no G toxicity.
Commercially, Glyceryl Stearate (Glycerol monostearate) is synthesized from mono triglycerides, diglycerides, and triglycerides of palmitic acid and stearic acid.
Glyceryl Stearate (Glycerol monostearate) is often used as an emulsifier to stabilize the product and prevent separation.
Glyceryl Stearate (Glycerol monostearate) is found in many personal care products such as moisturizers, eye creams, sunscreens, cosmetics, and hand creams.
Glyceryl Stearate (Glycerol monostearate) is also used as a preservative.

Production Methods
Glyceryl Stearate (Glycerol monostearate) is prepared by the reaction of glycerin with triglycerides from animal or vegetable sources, producing a mixture of monoglycerides and diglycerides.
The diglycerides may be further reacted to produce the 90% monoglyceride grade.
Another process involves reaction of glycerol with stearoyl chloride.
The starting materials are not pure substances and therefore the products obtained from the processes contain a mixture of esters, including palmitate and oleate.
Consequently, the composition, and therefore the physical properties, of Glyceryl Stearate (Glycerol monostearate) may vary considerably depending on the manufacturer.

Pharmaceutical Applications
The many varieties of Glyceryl Stearate (Glycerol monostearate) are used as nonionic emulsifiers, stabilizers, emollients, and plasticizers in a variety of food, pharmaceutical, and cosmetic applications.
Glyceryl Stearate (Glycerol monostearate) acts as an effective stabilizer, that is, as a mutual solvent for polar and nonpolar compounds that may form water-in-oil or oil-in-water emulsions.
These properties also make Glyceryl Stearate (Glycerol monostearate) useful as a dispersing agent for pigments in oils or solids in fats, or as a solvent for phospholipids, such as lecithin.
Glyceryl Stearate (Glycerol monostearate) has also been used in a novel fluidized hot-melt granulation technique for the production of granules and tablets.
Glyceryl Stearate (Glycerol monostearate) is a lubricant for tablet manufacturing and may be used to form sustained-release matrices for solid dosage forms.

Sustained-release applications include the formulation of pellets for tablets or suppositories, and the preparation of a veterinary bolus.
Glyceryl Stearate (Glycerol monostearate) has also been used as a matrix ingredient for a biodegradable, implantable, controlledrelease dosage form.
When using Glyceryl Stearate (Glycerol monostearate) in a formulation, the possibility of polymorph formation should be considered.
The aform is dispersible and foamy, useful as an emulsifying agent or preservative.
The denser, more stable, b-form is suitable for wax matrices.
This application has been used to mask the flavor of clarithromycin in a pediatric formulation.

Synonyms
Glyceryl monostearate
123-94-4
Monostearin
GLYCEROL MONOSTEARATE
31566-31-1
Glyceryl stearate
Tegin
1-Stearoyl-rac-glycerol
1-MONOSTEARIN
Glycerin 1-monostearate
Stearin, 1-mono-
Stearic acid 1-monoglyceride
2,3-dihydroxypropyl octadecanoate
Glycerol 1-monostearate
1-Glyceryl stearate
Glycerin 1-stearate
Sandin EU
1-Monostearoylglycerol
Octadecanoic acid, 2,3-dihydroxypropyl ester
Aldo MSD
Aldo MSLG
Glyceryl 1-monostearate
Stearoylglycerol
Glycerol 1-stearate
alpha-Monostearin
Tegin 55G
Emerest 2407
Aldo 33
Aldo 75
Glycerin monostearate
Arlacel 165
3-Stearoyloxy-1,2-propanediol
Cerasynt SD
Stearin, mono-
2,3-Dihydroxypropyl stearate
.alpha.-Monostearin
Monoglyceryl stearate
Glycerol alpha-monostearate
Cefatin
Dermagine
Monelgin
Sedetine
Admul
Orbon
Citomulgan M
Drewmulse V
Cerasynt S
Drewmulse TP
Tegin 515
Cerasynt SE
Cerasynt WM
Cyclochem GMS
Drumulse AA
Protachem GMS
Witconol MS
Witconol MST
FEMA No. 2527
Glyceryl stearates
Monostearate (glyceride)
Unimate GMS
Glyceryl monooctadecanoate
Ogeen M
Emcol CA
Emcol MSK
Hodag GMS
Ogeen GRB
Ogeen MAV
Aldo MS
Aldo HMS
Armostat 801
Kessco 40
Stearic monoglyceride
Abracol S.L.G.
Arlacel 161
Arlacel 169
Imwitor 191
Imwitor 900K
NSC 3875
11099-07-3
Atmul 67
Atmul 84
Starfol GMS 450
Starfol GMS 600
Starfol GMS 900
Cerasynt 1000-D
Emerest 2401
Aldo-28
Aldo-72
Atmos 150
Atmul 124

aldo MSD KFG glycerol stearate SE hallstar GMS SE lipo GMS 470 pastilles lonzest GMR lonzest GMS-D nikkol MGS-150V nikkol MGS-AMV nikkol MGS-ASEV nikkol MGS-AV nikkol MGS-BMV nikkol MGS-BSEV nikkol MGS-BV2 nikkol MGS-DEXV nikkol MGS-F40V nikkol MGS-F50SEV nikkol MGS-F50V nikkol MGS-F75V norfox gms-fg octadecanoic acid ester with 1,2,3-propane triol octadecanoic acid; propane-1,2,3-triol stearine CAS Number 11099-07-3

SYNONYMS Glyceryl monostearate; 3-Stearoyloxy-1,2-propanediol; Glyceryl stearate; Alpha-Monostearin; Monostearin; Octadecanoic acid, 2,3-dihydroxypropyl ester; Glycerin 1-monostearate; Glycerin 1-stearate; Glycerol alpha-monostearate; Glyceryl 1-monostearate; Stearic acid alpha-monoglyceride; Stearic acid 1-monoglyceride; 1-Glyceryl stearate; 1-Monostearin; 1-Monostearoylglycerol; 1,2,3-Propanetriol 1-octadecanoyl ester; CAS NO. 123-94-4, 11099-07-3

SYNONYMS 1,2,3-Propanetriyl triacetate; Enzactin; Fungacetin; Glycerin triacetate; Triacetylglycerol; Glycerol triacetate; Glyceryl triacetate; Glyped; Kesscoflex TRA; Triacetine; Vanay; Glycerol triacetate tributyrin; Triacetyl glycerine; Propane-1,2,3-triyl triacetate CAS NO. 102-76-1

GLYCEROL TRIACETATE = TRIACETIN = 1,2,3-TRIACETOXYPROPANE


CAS Number: 102-76-1
EC Number: 203-051-9
MDL number: MFCD00008716
Linear Formula: (CH3COOCH2)2CHOCOCH3 / C9H14O6



Glyceryl triacetate is a natural product found in Vitis vinifera with data available.
Glyceryl triacetate is an organic compound which is widely used in food, flavors & fragrances, pharmaceutical, cigarette, plasticiser, foundry, and textiles.
Glyceryl triacetate is slightly miscible with water, carbon tetrachloride and carbon disulfide.


Glyceryl triacetate is miscible with acetone, ethanol, benzene and chloroform.
Glyceryl triacetate is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.
Glycerol triacetate is an organic compound, usually appearing in the form of a clear oily liquid with a mild creamy-fruity aroma.
Glyceryl triacetate is a clear, colourless acetate ester used for example in the manufacture of cigarette filters.


Glyceryl triacetate is a liquid and has been approved by the FDA as a food additive.
Glyceryl triacetate is a triglyceride obtained by acetylation of the three hydroxy groups of glycerol.
Glyceryl triacetate is more generally known as triacetin and glycerin triacetate.
Glyceryl triacetate is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.


Glyceryl triacetate is a colorless, viscous and odorless liquid with a high boiling point.
Glycerol triacetate, is the organic compound with the formula C3H5(OCOCH3)3.
Glycerol Triacetate is also known as triacetin, and Glycerol triacetate appears as a clear colorless oily liquid.
Glycerol triacetate is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.


Glycerol triacetate is however naturally available in butter, cod-liver oil and other fats as well.
Glycerol Triacetate is a polyol, an organic molecule with more than one OH group.
Glycerol triacetate is colorless transparent oily liquid,with bitter taste, nontoxic, slightly soluble in water, Soluble in many kinds of organic solvents. Boiling point:258º C(0.101mpa), flash point:140º C~143º C.


Glycerol triacetate is commercially prepared from acetic acid and glycerol.
Glycerol triacetate is insoluble in aliphatic hydrocarbons, mineral oils, and vegetable and animal oils.
Additionally, in a toxicology report from 2002, triacetin and a group of related triglycerides did not represent a hazard to human health based on the anticipated daily intake of 7.8 mg/day/adult, and other available data.


Glycerol triacetate is a triester of glycerin and acetic acid, the second simplest fat after triformin.
Glycerol triacetate is colorless transparent oily liquid with bitter taste, nontoxic, slightly soluble in water and carbon disulfide, soluble in many kinds of organic solvents.
Glycerol triacetate is a colorless, viscous, and odorless liquid with a high boiling point and a low melting point.


Glycerol triacetate has a mild, sweet taste in concentrations lower than 500 ppm, but may appear bitter at higher concentrations.
Glycerol triacetate, USP is used as a humectant excipient.
Naturally, Glycerol triacetate is present in fruits such as papaya.
Glycerol triacetate is also found in cod-liver oil, certain types of fats, and butter.


Glycerol triacetate is a natural product found in Vitis vinifera with data available.
Glycerol triacetate, also known as triacetin, is an oil.
Glycerol triacetate is a liquid, and has been approved by the FDA as a food additive.
Glycerol triacetate, 99% - is the triester of glycerol and acetylating agents, such as acetic acid and acetic anhydride.


Glycerol triacetate is a clear, colorless acetate ester used for plasticising synthetic rubber and cellulose derivatives.
Glycerol triacetate can also be prepared by the reaction of oxygen with a liquid-phase mixture of allyl acetate and acetic acid using a bromide salt as a catalyst.
Glycerol triacetate comes as colorless and odorless oil which is slightly soluble in water.


Glycerol triacetate is a tri-ester of glycerol and acetic acid.
Glycerol triacetate is one of the glycerine acetate compounds.
Glycerol Triacetate is colorless odorless oily liquid.
Glycerol triacetate is a triester of glycerin and acetic acid.


Glycerol triacetate, also known as enzactin or e 1518, belongs to the class of organic compounds known as triacylglycerols.
These are glycerides consisting of three fatty acid chains covalently bonded to a glycerol molecule through ester linkages.
Thus, Glycerol triacetate is considered to be a triradylglycerol.
Based on a literature review a significant number of articles have been published on Glycerol triacetate.


Glycerol triacetate is classified as a triglyceride, i.e., the triester of glycerol.
Glycerol triacetate has low solubility in water.
Glycerol triacetate has fungistatic properties (based on release of acetic acid).
Glycerol triacetate is colourless transparent oily liquid, with bitter taste, nontoxic, slightly soluble in water.


All Spectrum Chemical USP grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP).
Glycerol triacetate is listed on the FDA Generally Regarded As Safe (GRAS) List.
According to the FDA, triacetin has been found to be non-toxic in long-term feeding tests in rats at levels that were several orders of magnitude greater than those to which consumers are exposed.


Glycerol triacetate is also a component of casting liquor with TG.
Glycerol triacetate is readily soluble in aromatic hydrocarbons and most organic solvents.
Glycerol triacetate is miscibled With ethanol, ether, benzene, chloroform, most organic solvents, soluble in acetone, Insoluble in mineral oil.


Glycerol triacetate is a colorless, oily liquid that, although is most often synthesized, can be found naturally in cod-liver oil, butter, and other fats.
Glycerol triacetate is also generally recognized as safe in animal feeds, as a pesticide adjuvant, and in food packaging.
Glycerol triacetate is miscible with acetone, ethanol, benzene and chloroform.


Glycerol triacetate is soluble in many kinds of organic solvents.
Glycerol triacetate is an artificial chemical compound, is the triester of glycerol and acetic acid, and is the second simplest fat after triformin.


Glycerol triacetate is naturally present in fats such as cod liver oil and butter, but is typically synthesized for industry using glycerol (from plant-derived fats) and acetic acid (a weak acid found in vinegar).
Glycerol triacetate is a water-soluble short-chain triglyceride that may also have a role as a parenteral nutrient according to animal studies.
Chemically, Glycerol triacetate is produced by acetylation of the three hydroxy groups of glycerol.


Glycerol triacetate is slightly miscible with water, carbon tetrachloride and carbondisulfide.
Glycerol triacetate can be prepared by heating glycerin with acetic anhydride alone or in the presence of finely divided potassium hydrogen sulfate.


Glycerol triacetate has a GRAS (Generally Recognized As Safe) status from FDA.
Glycerol triacetate is synthesized triester of glycerol and acetic acid.
Viscous oily liquid that finds use as an emollient in topical formulations.


Glycerol triacetate is in a class of organic compounds known as triglycerides, which form the main constituents of vegetable oils and other fats.
Glycerol triacetate, 99% Cas 102-76-1 - used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.


Glycerol triacetate (C8 H14O6, CAS Reg. No. 102-76-1), also known as 1,2,3,-propanetriol triacetate or Triacetin, is the triester of glycerin and acetic acid.
Glycerol triacetate is colourless with a fruity aroma.
Reportedly Glycerol triacetate has been used for more than 75 years with a large variety of uses and applications.



USES and APPLICATIONS of GLYCERYL TRIACETATE:
Glycerol triacetate is a commonly used carrier for flavors and fragrances.
Glycerol triacetate is an artificial chemical compound, commonly used as a food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.
Glycerol triacetate is applied to the filter as a plasticizer.


Glyceryl triacetate is used for the solidification of acetyl cellulose fibres in the manufacture of cigarette filters.
The water content must be kept constant to achieve constant solidification.
Glyceryl triacetate is also used as a support for flavourings and essences in the food industry and as a plasticiser for chewing gum.
In technical applications, Glyceryl triacetate is used for example as a core sand binder in the metal foundry sector.


Another application of Glyceryl triacetate is inks and printing inks.
Glycerol triacetate is mainly used as a plasticiser in adhesive and construction applications.
Glyceryl triacetate is used as a highly effective plasticiser for cellulose-based plastics.
Glyceryl triacetate is also used for plasticising NBR and cellulose derivatives.


Glyceryl triacetate is used as a food additive and as a solvent in flavorings.
Glycerol triacetate is used as solvent in building wall coating.
Glyceryl triacetate acts as an excipient in pharmaceutical products where it is used as a humectant and a plasticizer.


Glyceryl triacetate is also used as a fuel additive, as an antiknock agent, adhesives and sealant chemicals, fillers, intermediates and process regulators.
Glyceryl triacetate is used as a food additive and as a solvent in flavorings.


Glycerol triacetate, E1518, can be used in Food, Beverage, Pharmaceutical, Health & Personal care products, Agriculture/Animal Feed/Poultry.
Glycerol triacetate is useful for imparting plasticity and flow to laminating resins, particularly at low temperatures, and Glycerol triacetate is also used as a plasticizer for vinylidene polymers and copolymers.


Glycerol triacetate kills the bacteria that are thriving on skin or product and carries out antimicrobial actin.
Glyceryl triacetate acts as an excipient in pharmaceutical products where it is used as a humectant and a plasticizer.
Glyceryl triacetate is also used as a fuel additive, as an antiknock agent, adhesives and sealant chemicals, fillers, intermediates and process regulators.


Glyceryl triacetate has fungistatic properties (based on release of acetic acid) and has been used in the topical treatment of minor dermatophyte infections.
Glyceryl triacetate has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug.


Glyceryl triacetate is functionally related to an acetic acid.
Glyceryl triacetate is a water-soluble short-chain triglyceride that may also have a role as a parenteral nutrient according to animal studies.
Glycerol triacetate has antimicrobial properties and because of Glycerol triacetate's hygroscopic effect Glycerol triacetate is used as a humectant in the chocolate and pastry industry.


Other fields of application include solvent in foundry, ink and printing ink industry.
Glyceryl triacetate is also used in the perfume and cosmetic industries.
Glycerol triacetate is used Component of casting liquor used as a plasticizer and solvent, Food additive as humectant, Plasticizer applied to the cigarette filter, and Flavor and essence fixative and lubricate in cosmetics.


Glyceryl triacetate is used as an ingredient in many food and cosmetic products.
Its high solubility and low volatility make Glyceryl triacetate a good solvent and stabilizer for many flavors and odors.
One of Glyceryl triacetate's main uses is chewing gums as a plasticizer.
The United States Food and Drug Administration has confirmed that Glyceryl triacetate is generally considered safe (GRAS) for use in human foods.


Glycerol triacetate acts as an excipient in pharmaceutical products where Glycerol triacetate is used as a humectant and a plasticizer.
Glyceryl triacetate is also considered safe for use in animal feeds, as pesticides, and in food packaging.
Glyceryl triacetate can also be used as an anti-knock agent in gasoline, reducing engine knock and improving the cold and viscosity properties of biodiesel.


Glyceryl triacetate (triacetin) is an aromatic chemical compound commonly used as a food additive.
For example, Glyceryl triacetate is used as a solvent and humectant in sweeteners.
Glycerol triacetate is also used a cosmetic biocide, i.e.


Glycerol triacetate is used Fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and Fuel additive to improve cold flow and viscosity properties of biodiesel.
Glyceryl triacetate is also used as a humectant, plasticizer and solvent auxiliaries in pharmaceutical products.


Glyceryl triacetate is used as a plasticizer and odor stabilizer, ink solvent, also in drug and dye synthesis,
Glyceryl triacetate is used as chromatographic fixative, solvent, hardener and odor stabilizer.
Glycerol triacetate is used as an antimicrobial, a film former and a solvent.


Glycerol triacetate is also used as a fuel additive, as an antiknock agent, adhesives and sealant chemicals, fillers, intermediates and process regulators.
Glycerol triacetate has a role as a plant metabolite, a solvent, a fuel additive, an adjuvant, a food additive carrier, a food emulsifier, a food humectant and an antifungal drug.


Glycerol triacetate derives from an acetic acid.
Glyceryl triacetate is used as Humidifiers; carrier solvents; as plasticizer, (can absorb carbon dioxide from natural gas.)
Glyceryl triacetate is used In the manufacture of cosmetics, pharmaceuticals and paints, as a plasticizer for cigarette filter rods, In cosmetics, casting, medicine, paint and other industries.


Food Grade is used as an ingredient in many food and cosmetic products.
Glycerol triacetate is used as plasticizer and solvent of printing ink, coated, cellulose nitrate and cellulose acetate.
Glyceryl triacetate is used as substrate for lipase, perfume fixative, solvent, gas chromatographic fixative (85℃, solvent: methanol, chloroform maximum temperature), gas and aldehyde analysis separation.


Glyceryl triacetate is used as Plasticizing NBR and cellulose derivatives, Core sand binder in the metal foundry applications, Coatings, Inks, Adhesives & Sealants, Rubber, Plastics, Water-based adhesives – PVA, VAE and Acrylic based systems, Pressure Sensitive Adhesive systems, Coatings – plasticizer for all types of Cellulosic resins.


Glycerol triacetate can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.
Glycerol triacetate is used as an excipient in pharmaceutical products, where Glycerol triacetate is used as a humectant, a plasticizer, and as a solvent.


Glycerol triacetate is used in cosmetics, nail polish, nail enamel remover, and make-up.
In technical applications Glycerol triacetate is applied as a highly effective plasticizer for coatings and adhesives, as an additive for special hardeners or also for the production of cigarette filters on the basis of cellulose acetate (filter tow).


Glyceryl triacetate is used Printing Inks and Graphic Arts, Cosmetics, Food additive, Fuel additive (anti-knocking agent), Cigarette Filter Tips, As fixative in perfumery, Solvent in manuf celluloid, Photographic films, Solvent in Flavorings, Chewing Gum, Humectant, Pharmaceuticals, Plasticizer, Fuel Additive, Cosmetic Products.


Glycerol triacetate is also used as plasticizer and solvent of printing ink, coating, cellulose nitrate, cellulose acetate, ethyl cellulose and cellulose acetate butyrate.
Glycerol triacetate is used as a food additive and as a solvent in flavorings.


Glycerol triacetate is a common food additive, for instance as a solvent in flavourings, and for its humectant function, with E number E1518 and Australian approval code A1518.
Glycerol triacetate acts as an excipient in pharmaceutical products where Glycerol triacetate is used as a humectant and a plasticizer.


Glycerol triacetate has been used for over 75 years for a wide range of uses, including cosmetic biocide (most often as a fungicide), plasticizer, solvent in cosmetic formulas, food additive (as a flavoring agent and adjuvant), and as a binder for combustible material in solid-rocket propellants.


Glyceryl triacetate is used flavor (E-1518), as a plasticizer for acrylic fabric filters (filter cigarette), as fragrance in perfumes, as a moisturizer in cosmetics, hardener in the casting of plastics, as the solvent in the composition fuel.
Glycerol triacetate is a colourless, oily liquid, odourless, immiscible in water.


Glycerol triacetate, also known as Triacetin, is a cosmetic biocide, plasticizer, and solvent in cosmetic formulations, at concentrations ranging from 0.8% to 4.0%.
Glycerol triacetate is also used as a fuel additive, as an antiknock agent, adhesives and sealant chemicals, fillers, intermediates and process regulators.


In the creation of our essential oil fragrances, Glycerol triacetate is used as a solvent and fixative.
Glycerol triacetate finds application in many industries, including pharmaceutical, cosmetic, food, cigarette, textile, and foundry, as a solvent and plasticizer agent.
Glycerol triacetate is used as solvent in printing inks.


In the food and perfume industry, among other applications, Glycerol triacetate is used as a solvent and solubilizer for fragrances and flavors, or as a plasticizer for chewing gum.
This aids in balancing the volatility of the oils (the rate at which the essential oils evaporate at room temperature), which helps to boost the longevity of the fragrance.


Glyceryl triacetate is used hardener in the production of various resins (epoxy, etc. karbamidofuranovyh), as a composite material in the manufacture of casings for sausages - with its addition they needed longer retain moisture.
Glyceryl triacetate is used in the confectionary industry to impart pomp and shape retention.
Glycerol triacetate is widely used as Plasticizer For cigarette filter tips, Baked Goods, Beverages, Chewing Gum, Flavouring Agent Confections, Dairy


Desserts, Hard Candy, Humectant, cosmetic, painting industry, Medicine, spice.
Glycerol triacetate is mainly used as filter tip of cigarette- plasticizer of secondary cellulose.
Excipient in pharmaceutical products as a humectant, a plasticzer and a solvent.
Glycerol triacetate is also used as an additive in food and cosmetics.


Glycerol triacetate is used in the topical treatment of minor dermatophyte infections.
Glyceryl triacetate is used Manufacturing of fragrances, Manufacturing of flavors, Chemical synthesis, Catalysis and Chemicals Processing, Manufacturing of plastics, Polymeres, Polymer auxiliaries, Plasticizers for polymers, Pigments and optical brighteners, Manufacturing of dyestuffs, and Dyestuffs


The plasticizing capabilities of Glycerol triacetate have been utilized in the synthesis of a biodegradable phospholipid gel system for the dissemination of the cancer drug paclitaxel (PTX).
Glycerol triacetate was combined with PTX, ethanol, a phospholipid and a medium chain triglyceride to form a gel-drug complex.
Glycerol triacetate serves as an ingredient in inks for printing on plastics, and as a plasticizer in nail polish.


Glyceryl triacetate is used Metal industry, Metal processing, Packaging industry, Carrier for fragrances, Cosmetics, and Flavor and fragrances.
Technical triacetin (a mixture of mono-, di-, and small quantities of triacetin) as a solvent for basic dyes, particularly indulines, and tannin in dyeing.
In Agriculture/Animal Feed/Poultry feed: Glycerol triacetate can be used as feed ingredients in agriculture/animal feed/poultry feed.


Glyceryl triacetate is used Glycerol triacetate for biochemistry.
Glycerol triacetate is used as an emollient and thickening agent in cosmetics.
Glycerol triacetate has been used as a plasticizer in the tests of acrylic polymer films for drug delivery.
Glycerol triacetate is used as a solvent for flavours; it also has some anti-fungal activity.


Glycerol triacetate is used as a highly effective plasticizer for cellulose-based plastics.
Glycerol triacetate complies with the European Pharmacopoeia and is approved in the EU as a food additive E 1518.
Glycerol triacetate's high solvency power and low volatility make triacetin a good solvent and fixative for many flavors and fragrances.


Glycerol triacetate is often used as a food additive, for instance as a solvent in flavourings, and for Glycerol triacetate's humectant function.
Glycerol triacetate is mainly used as filter tip of cigarette- plasticizers of secondary cellulose.
Glycerol triacetate is used as a solvent for fragrance, flavors, and for certain inks, Glycerol triacetate is used as a solubilized.


Glycerol triacetate is also used as a plasticizer, which gives the product texture that is smooth and appealing to the eye, without breaking a film.
Glycerol triacetate is used as an inactive ingredient additive in some drug formulations.
In Beverage: Glycerol triacetate can be used as emulsifier, flavor enhancer in beverage.


Food grade Glycerol triacetate, E1518, used in manufacturing of capsules and tablets, used as a humectant, plasticizer, and solvent, used in Tobacco industry, Dairy food, hard candy, butter and beverage, Chewing gum, Bakes food.
Glycerol triacetate has been considered as a possible source of food energy in artificial food regeneration systems on long space missions.
Glycerol triacetate is believed to be safe to get over half of one's dietary energy from triacetin.


Glycerol triacetate is a triglyceride that is used as an antifungal agent.
Glycerol triacetate can be also used as flavor, essence, fixative and lubricate of cosmetic, production of pharmaceuticals and dyes.
Glycerol triacetate manufactured by Polynt Group is available in three main grades, depending on the final application: technical grade, filter grade, and pharma grade.


One of Glycerol triacetate's main uses is as a plasticizer in chewing gum.
Glycerol triacetate can also be used as a fuel additive as an antiknock agent which can reduce engine knocking in gasoline, and to improve cold and viscosity properties of biodiesel.
Glycerol triacetate is used as a food additive and as a solvent in flavorings.


Glycerol triacetate is also used in the perfume and cosmetic industries.
Glycerol triacetate is used as core sand binder in metal foundry sector.
Glycerol triacetate (C9H14O6), also known as glyceryl triacetate, is pharmaceutical excipient used in manufacturing of capsules and tablets, and has been used as a humectant, plasticizer, and solvent.


Glycerol triacetate is also used as flavor, essence, fixative and lubricate of cosmetics.
Glycerol triacetate is mainly used in dairy products, cheese, processed fruit, dried vegetables, confectionery, etc.
Glycerol triacetate is used as a plasticizer for cellulosic resins and is compatible in all proportions with cellulose acetate, nitrocellulose, and ethyl cellulose.


-Industry Uses of Glycerol triacetate:
*Adhesives and sealant chemicals
*Agricultural chemicals (non-insecticide) finishing agents
*Intermediates
*Oxidizing / reducing agents
*Paint additives and coating additives not described by other categories plasticizers
*Processing aids not otherwise listed
*Solvents (becomes part of product formulation or mix) building, casting, refractive coating


-Wetting agent:
Beverages:
Glycerol triacetate is used in small amounts in foods and drinks to reduce the surface tension of water.


-Cosmetic Uses of Glycerol triacetate:
*antimicrobial agents:
*Film formers
*Fragrance
*Plasticisers
*Solvents


-Food ingredients:
*HTF - food/feed/beverage processing
*Other-food chemicals
*Packaging inks non food contact


-Consumer Uses of Glycerol triacetate:
*Adhesives and sealants
*Agricultural products (non-pesticidal)
*Construction / building materials (not covered in another group)
*Cleaning and care products
*Fabric, textile and leather products (not covered in another group)
food and drink
*Food ingredients
food packaging
*Lawn and garden care products
*Metal products (not covered in another group)
*Non-TSCA use paints and coatings paper products
*Photographic materials, film and photographic chemicals
*Plastic and rubber products not found elsewhere plasticizer
*water treatment products


-Glycerol triacetate is used as:
*cellulose plasticizer for cigarette filters
*in binders for solid rocket fuels
*as fixative in perfumes; to make cosmetics and pharmaceuticals
*as solvent for celluloid and photographic films
*to remove carbon dioxide from natural gas
*as topical antifungal medication
*Technical triacetin (mixture of mono-, di-, and small quantities of triacetin) used as a solvent for basic dyes (especially indulines) and tannin in dyeing
*Used in cigarette filters


-In Health and Personal care use of Glycerol triacetate:
*Glycerol triacetate, an oil, is the triester of Glycerol and Acetic Acid.
*In cosmetics and personal-care products, Glycerol triacetate is used in makeup as well as in nail polish and nail enamel removers.
*Glycerol triacetate helps cleanse the skin or prevent odor by destroying or inhibiting the growth of microorganisms.
*Glycerol triacetate is also a plasticizer and commonly used carrier for flavors and fragrances.


-In Pharmaceutical:
Glycerol triacetate can be used as an excipient in pharmaceutical products, where Glycerol triacetate is used as a humectant, a plasticizer, and as a solvent in Pharmaceutical.
-In Food:
Glycerol triacetate, E1518, can be used as humectant, emlusifier, binder in food such as in baked goods, beverages, chewing gum, flavoring agents, dairy desserts, cheese, processed fruit, dried vegetables, confectionery.


-Additionally, Glycerol triacetate has been used:
*To assist as a plant metabolite
*As a fuel additive
*As a plasticiser
*As a binder for combustible material in solid-rocket propellants


-Pharmaceutically, Glycerol triacetate has been used:
*As a pharmaceutical excipient used in manufacturing of capsules and tablets
*In the topical treatment of minor dermatophyte infections, due to its fungistatic properties


-Cosmetically, Glycerol triacetate has been used:
*As a cosmetic biocide, mainly as a fungicide
*As a solvent in cosmetic formulas
*In the perfume and cosmetic industries, due to its soft fruity aroma


-Within food industries, Glycerol triacetate has been used:
*As a food additive, used as a flavouring agent and as an adjuvant
*As a food additive carrier
*As a food emulsifier
*As a food humectant



GENERAL PROPERTIES of GLYCEROL TRIACETATE:
The major features of Glyceryl triacetate are :
*excellent suitability for the solidification of acetyl cellulose fibres for the manufacture of cigarette filters
*very good dissolving power for a number of organic substances
*good plasticising effect for various plastics such as celluloseacetates or celluloseacetobutyrates
*good plasticising effect for cellulose-based paints
*good compatibility with natural and synthetic rubber
*good light resistance



PROPERTIES and BENEFITS of GLYCEROL TRIACETATE:
-Excellent suitability for the solidification of acetyl cellulose fibers
-Very good dissolving power for a number of organic substances
-Good plasticizing effect for various plastics and cellulose-based paints
-Good compatibility with natural and synthetic rubber
-Good light resistance
-Very good dissolving power for a number of organic substances
-Good plasticizing effect for various plastics such as cellulose acetates or cellulose acetobutyrates
-Good plasticizing effect for cellulose-based paints
-Good compatibility with natural and synthetic rubber
-Good light resistance
-Excellent suitability for the solidification of acetyl cellulose fibers for the manufacture of cigarette filters



SYNTHESIS of GLYCEROL TRIACETATE:
Glycerol triacetate was first prepared in 1854 by the French chemist Marcellin Berthelot.
Glycerol triacetate was prepared in the 19th century from glycerol and acetic acid.
Glycerol triacetate's synthesis from acetic anhydride and glycerol is simple and inexpensive.
3 (CH3CO)2O + 1 C3H5(OH)3 → 1 C3H5(OCOCH3)3 + 3 CH3CO2H
This synthesis has been conducted with catalytic sodium hydroxide and microwave irradiation to give a 99% yield of triacetin.
Glycerol triacetate has also been conducted with a cobalt(II) Salen complex catalyst supported by silicon dioxide and heated to 50 °C for 55 minutes to give a 99% yield of triacetin.



ALTERNATIVE PARENTS of GLYCEROL TRIACETATE:
*Tricarboxylic acids and derivatives
*Carboxylic acid esters
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS of GLYCEROL TRIACETATE:
*Triacyl-sn-glycerol
*Tricarboxylic acid or derivatives
*Carboxylic acid ester
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of GLYCERYL TRIACETATE:
Molecular Weight: 218.20
XLogP3: 0.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 8
Exact Mass: 218.07903816
Monoisotopic Mass: 218.07903816
Topological Polar Surface Area: 78.9 Ų
Heavy Atom Count: 15
Formal Charge: 0
Complexity: 229
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Molecular Weight: 218.20
Physical state: clear, liquid
Color: colorless
Odor: fatty odor
Melting point/freezing point:
Melting point/range: ca.-78 °C at ca.1.013 hPa
Initial boiling point and boiling range: 258 - 260 °C - lit.
Flammability (solid, gas): No data available
Flash point 148 °C - closed cup
Autoignition temperature: 433 °C at 1.013 hPa
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 58 g/l at 25 °C
Partition coefficient: n-octanol/water

log Pow: 0,25 - Bioaccumulation is not expected.
Vapor pressure: 0,003 hPa at 25 °C
Density: 1,158 g/mL at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Min. Purity Spec: 99.5% (GC)
Physical Form (at 20°C): Colorless clear liquid
Melting Point: 3°C
Boiling Point: 257-258°C
Flash Point: 138°C
Density: 1.16

Refractive Index: 1.43
Long-Term Storage: Store long-term in a cool, dry place
Appearance: colorless clear oily liquid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Specific Gravity: 1.15900 to 1.16400 @ 25.00 °C.
Pounds per Gallon - (est).: 9.644 to 9.686
Refractive Index: 1.42900 to 1.43200 @ 20.00 °C.
Melting Point: 3.00 to 4.00 °C. @ 760.00 mm Hg
Boiling Point: 258.00 to 260.00 °C. @ 760.00 mm Hg
Boiling Point: 130.00 to 131.00 °C. @ 7.00 mm Hg
Acid Value: 1.00 max. KOH/g
PH Number: 7.00
Vapor Pressure: 0.014000 mmHg @ 25.00 °C. (est)
Vapor Density: 7.52 ( Air = 1 )

Flash Point: 280.00 °F. TCC ( 137.78 °C. )
logP (o/w): 0.250
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Acidity (as Acid): ≤ 0.02
Water content (wt),%: ≤ 0.1
Refractive index (25º C/D): 1.430～1.435
Relative density (25/25º C): 1.154～1.164
Soluble in:
alcohol
water, 2.152e+004 mg/L @ 25 °C (est)
water, 5.80E+04 mg/L @ 25 °C (exp)



FIRST AID MEASURES of GLYCERYL TRIACETATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of GLYCERYL TRIACETATE:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of GLYCERYL TRIACETATE:
-Extinguishing media:
--Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
--Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of GLYCERYL TRIACETATE:
-Control parameters:
Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Use impervious clothing.
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of GLYCERYL TRIACETATE:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.



STABILITY and REACTIVITY of GLYCERYL TRIACETATE:
-Reactivity:
No data available
-Chemical stability
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
triacetin
102-76-1
Glyceryl triacetate
Glycerol triacetate
Enzactin
Glycerin triacetate
Triacetine
Triacetylglycerol
Fungacetin
Glyped
Triacetyl glycerine
Vanay
Kesscoflex TRA
Kodaflex triacetin
1,2,3-Propanetriol, triacetate
1,2,3-triacetoxypropane
Acetin, tri-
propane-1,2,3-triyl triacetate
1,2,3-Propanetriol, 1,2,3-triacetate
Triacetina
Triacetinum
1,2,3-Propanetriol triacetate
Triacetin [INN]
Ujostabil
Estol 1581
FEMA No. 2007
Triacetyl glycerin
Triacetyl glycerol
1,2,3-Propanetriyl triacetate
1,2,3-Triacetylglycerol
2,3-diacetyloxypropyl acetate
Glyceryltriacetate
NSC 4796
Triacetin (USP/INN)
Acetic, 1,2,3-propanetriyl ester
ENZACTIN (TN)
NSC-4796
Ins no.1518
1,2,3-triacetyl-glycerol
2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate
Ins-1518
1,2,3-triacetyl-sn-glycerol
CHEBI:9661
XHX3C3X673
E1518
E-1518
NCGC00091612-04
Triacetin (1,2,3-Propanetriol triacetate)
DSSTox_CID_6691
DSSTox_RID_78184
DSSTox_GSID_26691
FEMA Number 2007
CAS-102-76-1
HSDB 585
EINECS 203-051-9
TRIACETIN (GLYCEROL TRIACETATE)
BRN 1792353
Triacetin [USP:INN:BAN]
UNII-XHX3C3X673
Enzacetin
Euzactin
Fungacet
Motisil
Blekin
tri-acetin
AI3-00661
CCRIS 9355
Triacetin, CP
Triacetin, FCC
Triacetin, US
3-Triacetoxypropane
Glycerine triacetate
MFCD00008716
Triacetin, 99%
Spectrum_000881
Spectrum2_000939
Spectrum3_001368
Spectrum4_000362
Spectrum5_001376
EC 203-051-9
Triacetin, >=99.5%
SCHEMBL3870
BSPBio_002896
Glycerol triacetate tributyrin
KBioGR_000823
KBioSS_001361
4-02-00-00253 (Beilstein Handbook Reference)
MLS002152946
1,3-Propanetriol, triacetate
DivK1c_000740
Glyceryl triacetate, >=99%
SPECTRUM1500585
Triacetin, analytical standard
SPBio_000878
Triacetin, 99%, FCC, FG
1,2,3-propanediol triethanoate
CHEMBL1489254
DTXSID3026691
FEMA 2007
HMS502E22
KBio1_000740
KBio2_001361
KBio2_003929
KBio2_006497
KBio3_002116
NSC4796
NINDS_000740
HMS1921G05
HMS2092O09
HMS2232I22
Pharmakon1600-01500585
Triacetin, >=99%, natural, FG
HY-B0896
ZINC1530705
Tox21_111155
Tox21_201745
Tox21_300111
WLN: 1VO1YOV1 & 1OV1
CCG-39680
LMGL03012615
NSC757364
s4581
Triacetin, 8CI, BAN, INN, USAN
1,2,3-Propanetriol triacetate, 9CI
AKOS009028851
Tox21_111155_1
Glyceryl triacetate, >=99.0% (GC)
NSC-757364
1,3-bis(acetyloxy)propan-2-yl acetate
IDI1_000740
NCGC00091612-01
NCGC00091612-02
NCGC00091612-03
NCGC00091612-05
NCGC00091612-06
NCGC00091612-07
NCGC00091612-09
NCGC00254207-01
NCGC00259294-01
LS-13668
SMR001224538
SBI-0051540.P002
FT-0626753
G0086
EN300-19216
D00384
E 1518
E75962
Q83253
AB00052112_06
A800614
SR-05000002079
J-000781
SR-05000002079-1
2-(Acetyloxy)-1-[(acetyloxy)methyl]ethyl acetate #
Z104473192
Triacetin, GTA F.G (1,2,3-PROPANETRIOL TRIACETATE)
Triacetin, Pharmaceutical Secondary Standard
1,2,3-Propanetriol triacetate
Glycerol Triacetate, USP Grade(1.03000)
TRIACETINE
Glycerol triacetate
Glyceryl triacetate
propane-1,2,3-triyl triacetate
1,2,3-Triacetylglycerol
1,2,3-Triacetoxypropane
2,3-diacetyloxypropyl acetate
triacetin
glyceryl triacetate
glycerol triacetate
glycerin triacetate
enzactin
triacetine
triacetylglycerol
fungacetin
glyped, triacetyl glycerine
glycerine triacetate
triacetyl glycerine
acetin-tri
1,2,3-triacetoxypropane
1,2,3-propanetriol triacetate
1,2,3-propanetriyl triacetate
acetic-1,2,3-prepanetriyl ester
1,2,3-Propanetriol triacetate
1,2,3-Propanetriol triacetate, 9ci
1,2,3-Propanetriol triacetate, 9CI
1,2,3-Propanetriol triacetic acid
1,2,3-Propanetriol, 1,2,3-triacetate
1,2,3-Propanetriol, triacetate
1,2,3-Propanetriyl triacetate
1,2,3-Propanetriyl triacetic acid
1,2,3-Triacetoxypropane
1,3-bis(acetyloxy)propan-2-yl acetate
1,2,3-Triacetylglycerol
Acetin TP LXS 51035
Glycerinetriacetate
Glyceroltriacetate
1,2,3-Propanetriol Triacetate
1,3-Diacetyloxypropan-2-yl Acetate