Textile, Leather, Paper and Industrial Chemicals

VITAMİN E
Alpha-Tocopherol is the orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body. d-Alpha-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties. Considered essential for the stabilization of biological membranes (especially those with high amounts of polyunsaturated fatty acids), d-alpha-Tocopherol is a potent peroxyl radical scavenger and inhibits noncompetitively cyclooxygenase activity in many tissues, resulting in a decrease in prostaglandin production. Vitamin E also inhibits angiogenesis and tumor dormancy through suppressing vascular endothelial growth factor (VEGF) gene transcription. (NCI04) Vitamin E (alpha tocopherol) is a fat soluble vitamin and potent antioxidant that is believed to be important in protecting cells from oxidative stress, regulating immune function, maintaining endothelial cell integrity and balancing normal coagulation. There is no evidence that vitamin E, in physiologic or even super-physiologic, high doses, causes liver injury or jaundice. Vitamin E is a collective term used to describe 8 separate fat soluble antioxidants, most commonly alpha-tocopherol[A176104]. Vitamin E acts to protect cells against the effects of free radicals, which are potentially damaging by-products of the body's metabolism. Vitamin E deficiency is seen in persons with abetalipoproteinemia, premature, very low birth weight infants (birth weights less than 1500 grams, or 3½ pounds), cystic fibrosis, and cholestasis and severe liver disease[A176104]. Preliminary research suggests vitamin E may help prevent or delay coronary heart disease and protect against the damaging effects of free radicals, which may contribute to the development of chronic diseases such as cancer[A237]. It also protects other fat-soluble vitamins (A and B group vitamins) from destruction by oxygen[A239]. Low levels of vitamin E have been linked to increased incidence of breast and colon cancer[L5725]. Alpha-Tocopherol is the orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body. Vitamin E is likely the most important antioxidant in the human diet and alpha-tocopherol is the most active isomer. Alpha-tocopherol exhibits anti-oxidative capacity in vitro, and inhibits oxidation of ldl. Beside this, alpha-tocopherol shows anti-inflammatory activity and modulates expression of proteins involved in uptake, transport and degradation of tocopherols, as well as the uptake, storage and export of lipids such as cholesterol. Despite promising anti-atherogenic features in vitro, vitamin E failed to be atheroprotective in clinical trials in humans. Recent studies highlight the importance of long-chain metabolites of alpha-tocopherol, which are formed as catabolic intermediate products in the liver and occur in human plasma. These metabolites modulate inflammatory processes and macrophage foam cell formation via mechanisms different than that of their metabolic precursor alpha-tocopherol and at lower concentrations. Here we summarize the controversial role of vitamin E as a preventive agent against atherosclerosis and point the attention to recent findings that highlight a role of these long-chain metabolites of vitamin E as a proposed new class of regulatory metabolites. We speculate that the metabolites contribute to physiological as well as pathophysiological processes. Balanced nutrition is very important for maintaining health and strengthening the immune system as well as the daily functions of the body. The implementation of a nutrition program that is created with natural and healthy foods and that includes all food groups in moderation provides the body with the energy it needs and contains all nutrients in balanced proportions. Along with the foods consumed, the need for vitamins and minerals should be met in addition to the nutrients divided into three groups as protein, carbohydrate and fats. Vitamin E, one of the fat soluble vitamins; It is a nutrient that has important roles in many areas such as skin health, eye health and hormonal order. At the same time, vitamin E, one of the vitamins with antioxidant properties, is also very effective in strengthening the immune system. For this reason, it is important to take the vitamin E needed by the body regularly with foods. What is Vitamin E? Vitamin E is one of the basic types of vitamins, also called tocopherols, which are necessary for the daily functions of the body. Just like vitamins A, D and K, vitamin E is also fat-soluble and can be stored in the liver to some extent. This vitamin, which is absorbed from the small intestines after being taken with food, is a nutrient whose deficiency is less common than water-soluble vitamins due to its ability to be stored in the liver. In addition to the liver, some vitamin E can be stored in the heart, kidneys, adrenal glands, muscles and tissues. The only form of this vitamin, which has eight different forms, that can be used in the human body is the form called alpha tocopherol. Vegetable oils and vegetable foods containing valuable oils are among the main sources of vitamin E. Vitamin E can be taken into the body with foods, and in some cases, vitamin E can be taken into the body as supplements. The daily vitamin E requirement in adults is at the level of 10 mg for men and 8 mg for women. For children, the daily requirement varies between 3-10 mg depending on the age of the child. It is very important to meet this requirement on a daily basis. When vitamin E sources are not consumed in sufficient amounts for a long time or when vitamin E deficiency develops due to some diseases, some health problems begin to occur. What are the benefits of vitamin E? Vitamin E has many important functions in the human body. In order for many organs in the body to function properly, it is necessary to have sufficient vitamin E levels. This vitamin is also very important for the hormonal system to work properly. Especially in order to produce sex hormones in a healthy way, to prevent gynecological and urological diseases, and to increase reproductive ability, foods containing vitamin E should be consumed in sufficient amounts. At the same time, vitamin E, an antioxidant vitamin, prevents them from causing harmful effects on the body by reducing free radicals. In this way, it reduces oxidative stress and helps fight many diseases, especially cancer, by preventing the formation of genetic damage in cells. Vitamin E, which contributes to the strengthening of the immune system, contributes to the protection of the body against infectious diseases when taken in sufficient amount. Adequate vitamin E intake is also very important for eye and skin health. In order to maintain healthy eye development in children in the growth and development period, and to protect eye health in adult individuals, the daily vitamin E requirement should be fully met. In addition, it is important to meet the vitamin E requirement in terms of providing skin elasticity, increasing the renewal rate of the skin, obtaining a healthier skin appearance and preventing defects such as wrinkles. Some of the other benefits of vitamin E in the body are: Prevents cell damage: Thanks to its antioxidant properties, vitamin E prevents free radicals from damaging cells and causing cancer. In this way, it helps prevent cancer and cardiovascular diseases. Protects the skin against aging: Vitamin E, which has an important role in the protection of skin health, contributes to the protection of the moisture balance of the skin, the rapid healing of wounds and burns, and the prevention of wrinkles and other skin problems. At the same time, vitamin E, which provides protection against skin cancer, is included in many cosmetic products. Improves hair and nail health: Vitamin E; It helps hair grow healthily and quickly, as well as having a structure that is resistant to breakage and shedding. Vitamin E, which has positive effects in terms of nail health, helps nails to grow healthily while preventing yellowing, cracking and peeling. Reduces the effects of skin diseases such as eczema and psoriasis: The daily requirement for vitamin E is It helps to reduce the symptoms of dryness in skin diseases such as eczema and atopic dermatitis and to increase the moisture content of the skin. It also has important effects in reducing the complications seen in psoriasis and supporting treatment. What do you have vitamin E in? In order to meet the daily requirement of vitamin E, basic food types containing plenty of this vitamin must be present in the diet sufficiently. The most valuable sources of vitamin E; Vegetable oils such as olive oil, hazelnut oil, Oil seeds such as hazelnuts, almonds, walnuts, sunflower seeds, Vegetables and greens such as spinach, cress, parsley, lettuce, celery, cabbage, broccoli, pumpkin, Poultry, Fish species such as anchovy, salmon, mackerel, sardines and tuna, Fruits such as avocados, bananas and kiwi Cereals, Butter, Red meat, They are foods like eggs. Should vitamin E supplements be used? Vitamin E supplements or vitamin-mineral tablets containing this vitamin can be found in pharmacies and stores where wellness products are sold. However, with a healthy nutrition program that includes all food groups in balanced amounts, the vitamin E requirement can be fully met. For this reason, individuals who do not have a medical obstacle to consume vitamin E source foods do not need to use vitamin E supplements. As with all vitamins and minerals, it is healthier to meet vitamin E naturally. Therefore, it is not recommended to use vitamin and mineral supplements unconsciously for purposes such as protecting from diseases or strengthening the body without consulting a physician, and it should be known that excessive intake of vitamins and minerals can adversely affect health. In addition, vitamin E supplements can be prescribed for people with a diagnosis of vitamin E deficiency or for individuals who follow a special diet due to any disease and therefore cannot consume vitamin E resources sufficiently. These supplements are usually in the form of capsules and the frequency and dosage of use should be determined by the physician. Vitamin E deficiency is generally seen in those who do not consume enough vegetable oils, and those who follow diets with very low fat content. In addition, when vitamin E absorption from the intestines is not sufficient, vitamin E deficiency may develop in people with diseases related to the digestive system. Such situations can be counted among the situations where vitamin E supplements can be used with the doctor's recommendation. Vitamin E deficiency includes vision problems, weakness and fatigue, anemia, cracks in the skin and tongue, anemia, easy bruising on the skin, muscle and bone pain, muscle loss, nail and hair health deterioration. Since many of these symptoms are symptoms that can be seen in different diseases, people who experience symptoms should definitely apply to health institutions and undergo an examination. If you are experiencing symptoms of vitamin E deficiency, you can apply to a healthcare institution and have the necessary tests done. According to your examination and test results, you can find out whether you need vitamin supplements or not, and you can protect your health by paying attention to the recommendations given by your physician. What is Vitamin E? Vitamin E is an antioxidant. It supports the body's immune system and helps regenerate cells. In addition to being found naturally in many foods, it can also be taken as a nutritional supplement. Vitamin E is fat soluble. This means your body stores and uses it as needed. Which Foods Contain Vitamin E? Foods containing vitamin E can be listed as follows (2): Vegetable Oils: Wheat germ oil Sunflower oil Safflower oil corn oil Soybean Oil Dried Nuts: Almond Peanut Hazelnut Seeds: Sunflower seeds Green Leafy Vegetables: Spinach Broccoli Frequently Asked Questions What Are The Skin Benefits Of Vitamin E? Among the benefits of vitamin E to the skin; These include removing wrinkles, increasing the speed of skin renewal and ensuring the moisture balance of the skin. Is Vitamin E Applied To The Skin? How Is Vitamin E Applied To The Skin? Vitamin E can be applied to the skin through its liquid form in capsules or through moisturizing creams containing vitamin E. Click to view vitamin E capsules. Does Vitamin E Grow Hair? When vitamin E is applied to the scalp, it can help hair growth by increasing blood circulation and regulating the pH level. Vitamin E is a fat-soluble vitamin with several forms, but alpha-tocopherol is the only one used by the human body. Its main role is to act as an antioxidant, scavenging loose electrons—so-called “free radicals”—that can damage cells.It also enhances immune function and prevents clots from forming in heart arteries. Antioxidant vitamins, including vitamin E, came to public attention in the 1980s when scientists began to understand that free radical damage was involved in the early stages of artery-clogging atherosclerosis, and might also contribute to cancer, vision loss, and a host of other chronic conditions. Vitamin E has the ability to protect cells from free radical damage as well as stop the production of free radical cells entirely. However, conflicting study results have dimmed some of the promise of using high dose vitamin E to prevent chronic diseases. Food Sources Vitamin E is found in plant-based oils, nuts, seeds, fruits, and vegetables. Wheat germ oil Sunflower, safflower, and soybean oil Sunflower seeds Almonds Peanuts, peanut butter Beet greens, collard greens, spinach Pumpkin Red bell pepper Asparagus Mango Avocado Signs of Deficiency Because vitamin E is found in a variety of foods and supplements, a deficiency in the U.S. is rare. People who have digestive disorders or do not absorb fat properly (e.g., pancreatitis, cystic fibrosis, celiac disease) can develop a vitamin E deficiency. The following are common signs of a deficiency: Retinopathy (damage to the retina of the eyes that can impair vision) Peripheral neuropathy (damage to the peripheral nerves, usually in the hands or feet, causing weakness or pain) Ataxia (loss of control of body movements) Decreased immune function Toxicity There is no evidence of toxic effects from vitamin E found naturally in foods. Most adults who obtain more than the RDA of 22 IU daily are using multivitamins or separate vitamin E supplements that contain anywhere from 400-1000 IU daily. There have not been reports of harmful side effects of supplement use in healthy people. However, there is a risk of excess bleeding, particularly with doses greater than 1000 mg daily or if an individual is also using a blood thinning medication such as warfarin. For this reason, an upper limit for vitamin E has been set for adults 19 years and older of 1000 mg daily (1465 IU) of any form of tocopherol supplement. Vitamin E helps maintain healthy skin and eyes, and strengthen the body's natural defence against illness and infection (the immune system). Good sources of vitamin E Vitamin E is a group of compounds found in a wide variety of foods. Good sources include: plant oils – such as rapeseed (vegetable oil), sunflower, soya, corn and olive oil nuts and seeds wheatgerm – found in cereals and cereal product How much vitamin E do I need? The amount of vitamin E you need is: 4mg a day for men 3mg a day for women You should be able to get all the vitamin E you need from your diet. Any vitamin E your body does not need immediately is stored for future use, so you do not need it in your diet every day. What happens if I take too much vitamin E? There is not enough evidence to know what the effects might be of taking high doses of vitamin E supplements each day. What does the Department of Health and Social Care advise? You should be able to get the amount of vitamin E you need by eating a varied and balanced diet. If you take vitamin E supplements, do not take too much as this could be harmful. Taking 540mg (800 IU) or less a day of vitamin E supplements is unlikely to cause any harm. Vitamin E is found naturally in some foods, added to others, and available as a dietary supplement. “Vitamin E” is the collective name for a group of fat-soluble compounds with distinctive antioxidant activities. Naturally occurring vitamin E exists in eight chemical forms (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) that have varying levels of biological activity. Alpha- (or α-) tocopherol is the only form that is recognized to meet human requirements. Serum concentrations of vitamin E (alpha-tocopherol) depend on the liver, which takes up the nutrient after the various forms are absorbed from the small intestine. The liver preferentially resecretes only alpha-tocopherol via the hepatic alpha-tocopherol transfer protein; the liver metabolizes and excretes the other vitamin E forms. As a result, blood and cellular concentrations of other forms of vitamin E are lower than those of alpha-tocopherol and have been the subjects of less research. Vitamin E is a fat-soluble antioxidant that stops the production of ROS formed when fat undergoes oxidation. Scientists are investigating whether, by limiting free-radical production and possibly through other mechanisms, vitamin E might help prevent or delay the chronic diseases associated with free radicals. In addition to its activities as an antioxidant, vitamin E is involved in immune function and, as shown primarily by in vitro studies of cells, cell signaling, regulation of gene expression, and other metabolic processes. Alpha-tocopherol inhibits the activity of protein kinase C, an enzyme involved in cell proliferation and differentiation in smooth muscle cells, platelets, and monocytes. Vitamin-E–replete endothelial cells lining the interior surface of blood vessels are better able to resist blood-cell components adhering to this surface. Vitamin E also increases the expression of two enzymes that suppress arachidonic acid metabolism, thereby increasing the release of prostacyclin from the endothelium, which, in turn, dilates blood vessels and inhibits platelet aggregation. Recommended Intakes Intake recommendations for vitamin E and other nutrients are provided in the Dietary Reference Intakes (DRIs) developed by the Food and Nutrition Board (FNB) at the Institute of Medicine of The National Academies (formerly National Academy of Sciences). DRI is the general term for a set of reference values used to plan and assess nutrient intakes of healthy people. These values, which vary by age and gender, include: Recommended Dietary Allowance (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%–98%) healthy individuals; often used to plan nutritionally adequate diets for individuals. Adequate Intake (AI): Intake at this level is assumed to ensure nutritional adequacy; established when evidence is insufficient to develop an RDA. Estimated Average Requirement (EAR): Average daily level of intake estimated to meet the requirements of 50% of healthy individuals; usually used to assess the nutrient intakes of groups of people and to plan nutritionally adequate diets for them; can also be used to assess the nutrient intakes of individuals. Tolerable Upper Intake Level (UL): Maximum daily intake unlikely to cause adverse health effects. The FNB’s vitamin E recommendations are for alpha-tocopherol alone, the only form maintained in plasma. The FNB based these recommendations primarily on serum levels of the nutrient that provide adequate protection in a test measuring the survival of erythrocytes when exposed to hydrogen peroxide, a free radical. Acknowledging “great uncertainties” in these data, the FNB has called for research to identify other biomarkers for assessing vitamin E requirements. Naturally sourced vitamin E is called RRR-alpha-tocopherol (commonly labeled as d-alpha-tocopherol); the synthetically produced form is all rac-alpha-tocopherol (commonly labeled as dl-alpha-tocopherol). RDAs for vitamin E are provided in milligrams (mg) and are listed in Table 1. One mg vitamin E (alpha-tocopherol) is equivalent to 1 mg RRR-alpha-tocopherol or 2 mg all rac-alpha-tocopherol. Because insufficient data are available to develop RDAs for infants, AIs were developed based on the amount of vitamin E consumed by healthy breastfed babies. Food Numerous foods provide vitamin E. Nuts, seeds, and vegetable oils are among the best sources of alpha-tocopherol, and significant amounts are available in green leafy vegetables and fortified cereals (see Table 2 for a more detailed list). Most vitamin E in American diets is in the form of gamma-tocopherol from soybean, canola, corn, and other vegetable oils and food products. Dietary supplements Supplements of vitamin E typically provide only alpha-tocopherol, although “mixed” products containing other tocopherols and even tocotrienols are available. Naturally occurring alpha-tocopherol exists in one stereoisomeric form. In contrast, synthetically produced alpha-tocopherol contains equal amounts of its eight possible stereoisomers; serum and tissues maintain only four of these stereoisomers. A given amount of synthetic alpha-tocopherol (all rac-alpha-tocopherol; commonly labeled as “DL” or “dl”) is therefore only half as active as the same amount (by weight in mg) of the natural form (RRR-alpha-tocopherol; commonly labeled as “D” or “d”). Most vitamin-E-only supplements provide ≥67 mg (100 IU of natural vitamin E) of the nutrient. These amounts are substantially higher than the RDAs. Alpha-tocopherol in dietary supplements and fortified foods is often esterified to prolong its shelf life while protecting its antioxidant properties. The body hydrolyzes and absorbs these esters (alpha-tocopheryl acetate and succinate) as efficiently as alpha-tocopherol. Vitamin E Intakes and Status Three national surveys—the 2001–2002 National Health and Nutrition Examination Survey (NHANES), NHANES III (1988–1994), and the Continuing Survey of Food Intakes by Individuals (1994–1996) have found that the diets of most Americans provide less than the RDA levels of vitamin E. These intake estimates might be low, however, because the amounts and types of fat added during cooking are often unknown and not accounted for. The FNB suggests that mean intakes of vitamin E among healthy adults are probably higher than the RDA but cautions that low-fat diets might provide insufficient amounts unless people make their food choices carefully by, for example, increasing their intakes of nuts, seeds, fruits, and vegetables. The 1999–2000 NHANES found that 11.3% of adults took vitamin E supplements containing at least 400 IU. Vitamin E Deficiency Frank vitamin E deficiency is rare and overt deficiency symptoms have not been found in healthy people who obtain little vitamin E from their diets. Premature babies of very low birth weight (<1,500 grams) might be deficient in vitamin E. Vitamin E supplementation in these infants might reduce the risk of some complications, such as those affecting the retina, but they can also increase the risk of infections. Because the digestive tract requires fat to absorb vitamin E, people with fat-malabsorption disorders are more likely to become deficient than people without such disorders. Deficiency symptoms include peripheral neuropathy, ataxia, skeletal myopathy, retinopathy, and impairment of the immune response. People with Crohn’s disease, cystic fibrosis, or an inability to secrete bile from the liver into the digestive tract, for example, often pass greasy stools or have chronic diarrhea; as a result, they sometimes require water-soluble forms of vitamin E, such as tocopheryl polyethylene glycol-1000 succinate. Some people with abetalipoproteinemia, a rare inherited disorder resulting in poor absorption of dietary fat, require enormous doses of supplemental vitamin E (approximately 100 mg/kg or 5–10 g/day). Vitamin E deficiency secondary to abetalipoproteinemia causes such problems as poor transmission of nerve impulses, muscle weakness, and retinal degeneration that leads to blindness. Ataxia and vitamin E deficiency (AVED) is another rare, inherited disorder in which the liver’s alpha-tocopherol transfer protein is defective or absent. People with AVED have such severe vitamin E deficiency that they develop nerve damage and lose the ability to walk unless they take large doses of supplemental vitamin E. Vitamin E and Health Many claims have been made about vitamin E’s potential to promote health and prevent and treat disease. The mechanisms by which vitamin E might provide this protection include its function as an antioxidant and its roles in anti-inflammatory processes, inhibition of platelet aggregation, and immune enhancement. A primary barrier to characterizing the roles of vitamin E in health is the lack of validated biomarkers for vitamin E intake and status to help relate intakes to valid predictors of clinical outcomes. This section focuses on four diseases and disorders in which vitamin E might be involved: heart disease, cancer, eye disorders, and cognitive decline.
Vinyl neodecanoate
Vinyl neodecanoate ( Vinil neodekanoat) Vinyl neodecanoate, Vinil neodekanoat (trade name VeoVa 10) is a vinylic monomer that is virtually always used in combination with other monomers to create lattices or emulsion polymers.[3] Vinil neodekanoat The trade name is an acronym of Vinyl neodecanoate ester of Versatic Acid with the number 10 meaning 10 carbons in the molecule. It has a medium to low glass transition temperature of -3 °C. Chemically, it is a mixture of isomeric vinyl neodecanoate esters of neodecanoic acid. Vinyl neodecanoate(Vinil neodekanoat, veova 10) is mainly used as a modifying monomer in conjunction with other monomers and particularly the manufacture of vinyl neodecanoate acetate based polymer emulsions by the process of emulsion polymerization.[4] Vinyl neodecanoate-containing polymers (Vinil neodekanoat, veova 10) are used in decorative emulsion paints, plasters and renders especially in Europe.[5] Vinyl neodecanoate(Vinil neodekanoat, veova 10) is, like most vinyl neodecanoate ester monomers, is very hydrophobic and the structure is highly branched with a tertiary substituted α-carbon. It is used as a hydrophobic co-monomer. VeoVa 10 (Vinyl neodecanoate) Vinil neodekanoat This structure renders the polymers produced from it, very resistant to alkali degradation as there is no hydrogen (thus proton producing species) on the α-carbon. They have good resistance to degradation from ultraviolet light.[6] (Vinil neodekanoat, veova 10, Vinyl neodecanoate) The monomer has even been used to produce vibration dampening resins.[7] Property Test method Unit Value Molecular formula (theoretical) C12H22O2 Molecular mass (theoretical) 198 Added inhibitor (hydroquinone monomethyl ether) LPM 3112 mg/kg 5 +/-2 Kinematic viscosity at 20ºC ASTM D445 mm2 /s 2.2 Specific heat at 20ºC ASTM E1269 kJ/kg ºC 1.97 Latent heat of vaporisation at 20ºC kJ/mol 48.9 Boiling range ASTM D1078 ºC 133-136* Flash point (PMCC) ASTM D93 ºC 75 Pour point ASTM D97 ºC Below -60 Solubility in water at 20-80ºC % (m/m) <0.1 Solubility of water in monomer at 20-80ºC % (m/m) 0.05 Miscibility with vinyl neodecanoate acetate Completely miscible Specific heat of polymerisation ASTM E1269 kJ/mol 96 Copolymerisation parameters**, e Q -0.53 0.026 Glass transition temperature (Tg) of homopolymer *** (vinyl neodecanoate acetate homopolymer=32ºC) ASTM D3418 ºC -3 * measured at a reduced pressure (100 mm Hg) ** Using constants according to Young, J.Pol.Sci. 54,411, e=-0.22, Q = 0.026 for Vinyl neodecanoate acetate *** By differential scanning calorimetry (onset value 20ºC per minute). Test Methods ASTM Standards are published by the American Society for Testing and Materials, 100 Barr Harbor Drive, west Conshohocken, PA 19428-2959, USA. Transportation and Storage VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) Monomer should be stored at ambient temperature (min 5 °C - max 50 °C) in conditions such that moisture is excluded, in the original containers kept tightly closed. Under these conditions the shelf life should be a three years starting from the manufactured date. Handling Precautions For more detailed information on all aspects relating to Health, Safety and Handling, reference should be made to the Safety Data Sheet of VeoVa 10 (Vinyl neodecanoate) Vinil neodekanoat 10 monomer(Vinil neodekanoat, Vinyl neodecanoate) , VeoVa™ 10 monomer (Vinil neodekanoat, Vinyl neodecanoate) is the vinyl neodecanoate ester of Versatic™ acid 10. The homopolymer of VeoVa 10 monomer (Vinil neodekanoat, Vinyl neodecanoate) has a relatively low Tg of -3 °C. VeoVa 10 monomer (Vinil neodekanoat, Vinyl neodecanoate) can be used as a modifying comonomer in the preparation of vinyl neodecanoate acetate based polymer latices, which are used for the manufacture of high-quality emulsion paints. VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) vinyl neodecanoate ester is also used as a comonomer with acrylates for the production of emulsion and solution polymers. VeoVa 10 (Vinyl neodecanoate) Vinil neodekanoat VeoVa 10 chemical structure (Vinil neodekanoat, Vinyl neodecanoate) Reactive group (highlighted in yellow) Similar reactivity to vinyl neodecanoate acetate Excellent reactivity with ethylene Good reactivity with acrylate and methacrylate monomers Bulky group (highlighted in blue) Highly branched aliphatic structure Hydrophobic UV stable Performance Characteristics Alkali resistance Water repellency / Low surface tension Reduced water absorption Outdoor durability Improved adhesion on non-polar substrates Typical Applications Interior and exterior decorative paints Wood coatings Industrial coatings Redispersible powders and concrete admixtures Construction adhesives Wood adhesives Elastomeric roof coatings VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) is the vinyl neodecanoate ester of Versatic 10, a synthetic saturated monocarboxylic acid with a highly branched structure containing ten carbon atoms. VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) , a low viscosity liquid with a typical mild ester odor, is a very attractive monomer for the manufacture of polymers through reactions of the vinyl neodecanoate group(Vinil neodekanoat, veova 10, Vinyl neodecanoate) . It imparts a combination of flexibility (medium to low Tg), hydrophobicity and very good chemical and UV resistance Vinyl neodecanoate, Vinil neodekanoat (trade name VeoVa 10) is a vinylic monomer that is virtually always used in combination with other monomers to create lattices or emulsion polymers.[3] VeoVa 10 (Vinyl neodecanoate) Vinil neodekanoat The trade name is an acronym of Vinyl neodecanoate ester of Versatic Acid with the number 10 meaning 10 carbons in the molecule. It has a medium to low glass transition temperature of -3 °C. Chemically, it is a mixture of isomeric vinyl neodecanoate esters of neodecanoic acid. Vinyl neodecanoate(Vinil neodekanoat, veova 10) is mainly used as a modifying monomer in conjunction with other monomers and particularly the manufacture of vinyl neodecanoate acetate based polymer emulsions by the process of emulsion polymerization.[4] Vinyl neodecanoate-containing polymers (Vinil neodekanoat, veova 10) are used in decorative emulsion paints, plasters and renders especially in Europe.[5] Vinyl neodecanoate(Vinil neodekanoat, veova 10) is, like most vinyl neodecanoate ester monomers, is very hydrophobic and the structure is highly branched with a tertiary substituted α-carbon. It is used as a hydrophobic co-monomer. VeoVa 10 (Vinyl neodecanoate) Vinil neodekanoat This structure renders the polymers produced from it, very resistant to alkali degradation as there is no hydrogen (thus proton producing species) on the α-carbon. They have good resistance to degradation from ultraviolet light.[6] (Vinil neodekanoat, veova 10, Vinyl neodecanoate) The monomer has even been used to produce vibration dampening resins.[7] Property Test method Unit Value Molecular formula (theoretical) C12H22O2 Molecular mass (theoretical) 198 Added inhibitor (hydroquinone monomethyl ether) LPM 3112 mg/kg 5 +/-2 Kinematic viscosity at 20ºC ASTM D445 mm2 /s 2.2 Specific heat at 20ºC ASTM E1269 kJ/kg ºC 1.97 Latent heat of vaporisation at 20ºC kJ/mol 48.9 Boiling range ASTM D1078 ºC 133-136* Flash point (PMCC) ASTM D93 ºC 75 Pour point ASTM D97 ºC Below -60 Solubility in water at 20-80ºC % (m/m) <0.1 Solubility of water in monomer at 20-80ºC % (m/m) 0.05 Miscibility with vinyl neodecanoate acetate Completely miscible Specific heat of polymerisation ASTM E1269 kJ/mol 96 Copolymerisation parameters**, e Q -0.53 0.026 Glass transition temperature (Tg) of homopolymer *** (vinyl neodecanoate acetate homopolymer=32ºC) ASTM D3418 ºC -3 * measured at a reduced pressure (100 mm Hg) ** Using constants according to Young, J.Pol.Sci. 54,411, e=-0.22, Q = 0.026 for Vinyl neodecanoate acetate *** By differential scanning calorimetry (onset value 20ºC per minute). Test Methods ASTM Standards are published by the American Society for Testing and Materials, 100 Barr Harbor Drive, west Conshohocken, PA 19428-2959, USA. Transportation and Storage VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) Monomer should be stored at ambient temperature (min 5 °C - max 50 °C) in conditions such that moisture is excluded, in the original containers kept tightly closed. Under these conditions the shelf life should be a three years starting from the manufactured date. Handling Precautions For more detailed information on all aspects relating to Health, Safety and Handling, reference should be made to the Safety Data Sheet of VeoVa 10 (Vinyl neodecanoate) Vinil neodekanoat 10 monomer(Vinil neodekanoat, Vinyl neodecanoate) VeoVa™ 10 monomer (Vinil neodekanoat, Vinyl neodecanoate) is the vinyl neodecanoate ester of Versatic™ acid 10. The homopolymer of VeoVa 10 monomer (Vinil neodekanoat, Vinyl neodecanoate) has a relatively low Tg of -3 °C. VeoVa 10 monomer (Vinil neodekanoat, Vinyl neodecanoate) can be used as a modifying comonomer in the preparation of vinyl neodecanoate acetate based polymer latices, which are used for the manufacture of high-quality emulsion paints. VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) vinyl neodecanoate ester is also used as a comonomer with acrylates for the production of emulsion and solution polymers. VeoVa 10 chemical structure (Vinil neodekanoat, Vinyl neodecanoate) Reactive group (highlighted in yellow) Similar reactivity to vinyl neodecanoate acetate Excellent reactivity with ethylene Good reactivity with acrylate and methacrylate monomers Bulky group (highlighted in blue) Highly branched aliphatic structure Hydrophobic UV stable Performance Characteristics Alkali resistance Water repellency / Low surface tension Reduced water absorption Outdoor durability Improved adhesion on non-polar substrates Typical Applications Interior and exterior decorative paints Wood coatings Industrial coatings Redispersible powders and concrete admixtures Construction adhesives Wood adhesives Elastomeric roof coatings VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) is the vinyl neodecanoate ester of Versatic 10, a synthetic saturated monocarboxylic acid with a highly branched structure containing ten carbon atoms. VeoVa 10 (Vinil neodekanoat, Vinyl neodecanoate) , a low viscosity liquid with a typical mild ester odor, is a very attractive monomer for the manufacture of polymers through reactions of the vinyl neodecanoate group(Vinil neodekanoat, veova 10, Vinyl neodecanoate) . It imparts a combination of flexibility (medium to low Tg), hydrophobicity and very good chemical and UV resistance The neocarboxylic acid can be converted into its vinyl ester monomer by reaction with acetylene. Today, these monomers are marketed under the trade name VeoVa™ vinyl neodecanoate ester and are also widely referred to in industry as vinyl neodecanoate versatate monomers, neo-esters or VV monomers. VeoVa vinyl neodecanoate ester monomers are very hydrophobic vinyl neodecanoate esters with a highly branched tertiary substituted α-carbon structure. Their principal use is as hydrophobic co-monomers in vinyl neodecanoate and acrylic polymerization. Their alkyl neocarboxylic group is very resistant to degradation in alkaline conditions, as there is no hydrogen on the α-carbon atom. The branched tertiary structure with bulky and hydrophobic hydrocarbon groups provides the neo-ester monomers (Figure 2) with a highly hydrophobic nature and a low surface tension. Furthermore, they possess a strong resistance to hydrolysis and do not degrade under the influence of UV light. The VeoVa vinyl neodecanoate ester monomers easily polymerize with various other co-monomers through reaction of the vinyl ester functional group. In this way the specific properties of the monomer can be imparted to its copolymers. VeoVa monomer enhances the performance of vinyl neodecanoate acetate- and acrylic-based latices, significantly upgrading key properties such as water and alkali resistance in both polymer systems. VeoVa vinyl neodecanoate ester-based polymers exhibit the required polymer hardness and flexibility balance, hydrophobicity and chemical resistance for the formulation of a wide range of latex coatings. The resulting paints are characterized by very good water, UV and alkali resistance, and therefore exhibit very good outdoor durability.3 VeoVa monomers already have been successfully used to manufacture VeoVa/vinyl neodecanoate acetate copolymer latices. Used as binders for architectural paints, these latices provide improved scrub resistance and exterior durability. These properties of hydrophobicity, resistance to hydrolysis and UV light make VeoVa monomers also particularly suitable for producing high-performance latices, especially when they are copolymerized with acrylic and methacrylic monomers. VeoVa vinyl neodecanoate ester-modified acrylics can be formulated in protective coatings such as anti-corrosion paints, water-repellent systems, wood coatings, elastomeric roof coatings and adhesive applications such as PSAs. Glass Transition Temperature The various VeoVa monomers mainly differ in the degree of branching and the length of the hydrocarbon groups. This leads to differences in the glass transition temperature (Tg) of their homopolymers and consequently to different copolymer properties. The broad range of Tgs available within the portfolio of VeoVa monomers offers an important tool to the polymer chemist to develop hydrophobic polymers within a very wide Tg range. VeoVa 9 monomer is the vinyl neodecanoate ester of neononanoic acid (9 carbon atoms) and is considered a harder monomer as it imparts a Tg of +70 °C. Scholten and Van Westrenen illustrated the effect of chain branching by measuring the Tg of a series of polymer prepared from VeoVa 9 vinyl neodecanoate ester isomers.4 The Tgs were found to range from +10 to 119 °C, leading to the conclusion that the high Tg of poly-VeoVa 9 is a cumulative effect of the shorter chain length and the higher degree of branching within the various isomer mixtures. VeoVa 10 monomer is the vinyl neodecanoate ester of neodecanoic acid (10 carbon atoms) and has a homopolymer Tg of -3 °C, making it a flexibilizing monomer. VeoVa EH monomer is the vinyl neodecanoate ester of 2-ethylhexanoic acid, a more linear acid, and therefore has a significantly lower Tg of -36 °C Water Resistance Water resistance is one of the most important barrier properties of a coating. The water resistance of a coating is mainly governed by its polymeric binder and the monomers used to produce the binder. If water solubility of the monomers is taken as an indication of hydrophobicity (Table 1) it becomes clear that VeoVa monomers have a much higher hydrophobicity than other monomers that are commonly used in emulsion polymerization.5 Ease of Polymerization VeoVa monomers can be used in combination with a variety of other monomer types to produce various polymers. The ease of polymerization depends on the reactivity ratios of the monomers used (Table 2). The data reported in Table 2 show that VeoVa monomers have a similar reactivity to the vinyl neodecanoate acetate monomer. All the vinyl neodecanoate esters have a similar reactivity independent of the size of the carboxylic group. There is also a difference of reactivity between the vinyl neodecanoate ester monomers and (meth)acrylate monomers, but this difference is such that they can still react together in emulsion polymerization. Finally, the difference of reactivity between the vinyl neodecanoate ester monomers and styrene is so large that they cannot copolymerize in emulsion polymerization. In summary, the VeoVa monomers copolymerize easily with other vinyl neodecanoate esters, ethylene and most acetate-based and acrylic-based monomers. VeoVa-Modified Vinyl neodecanoate Acetate-Based Latices VV10 and vinyl neodecanoate acetate are very much complementary to each other with respect to the properties they impart to latex polymers. Vinyl neodecanoate acetate homopolymers, although economic in use, lack the flexibility and durability required for most emulsion paint applications. Homopolymers of VV10 (Table 3), on the other hand, exhibit very good resistance to hydrolysis, UV light and water, but having a Tg of -3 °C they are too soft for most coating applications. Copolymers of vinyl neodecanoate acetate and VV10 provide a well-balanced set of performance characteristics. Polyvinyl acetate has a Tg of +38 °C and is therefore brittle at ambient temperature. Co-polymerization of VV10 permanently flexibilizes the polymer and reduces the minimum film formation temperature (MFFT). Protective Effect of the VeoVa Vinyl Ester Molecule VV10 and vinyl neodecanoate acetate exhibit a very similar reactivity (r1=0.99; r2=0.92) in radical polymerization reactions, which leads to polymers with the monomer units randomly distributed along the chain. This is important, because it allows the key performance characteristics of the VV10 monomer to be fully exploited. The unique, highly branched, carbon-rich structure of the monomer sterically protects its ester group from being hydrolyzed. More importantly, it also protects neighboring acetate groups (Figure 3), thus improving the hydrolytic stability of the polymer. This protection phenomenon is referred to as the “umbrella effect”. This enables such polymers to be successfully used as paint binders on even very alkaline substrates. The umbrella protection effect of the highly branched carboxylate groups is supported by experimental data. The alkali resistance of a latex can be determined by the percentage of ester groups hydrolyzed after four days immersion in a 2% aqueous solution of sodium hydroxide. The results (Figure 4) show clearly that the introduction of VV10 in vinyl neodecanoate acetate-based polymers significantly improves the alkali resistance of both colloid-stabilized and colloid-free systems. While only 20% of VV10 already has a profound positive influence, a 30% use is recommended to obtain the very good alkali resistance required for high durability of emulsion paint on alkaline surfaces. Vinyl neodecanoate acetate homopolymer, as well as its copolymers with butyl acrylate or 2-ethylhexyl acrylate, tend to hydrolyze easily and almost completely with time. The data shows that the alkali resistance of a VA/VV10 (85/15) is significantly better compared to the alkali resistance of a VA/2-EHA (85/15), and the same is observed for a VA/VV10 (75/25) compared to a VA/BA (75/25). VV10 is therefore far more effective in protecting the acetate group than an acrylate monomer such as 2-ethylhexyl acrylate or butyl acrylate. This can be explained by the fact that the neo-acid structure is more bulky, apolar and more effectively randomly located onto the polymer backbone. Equally, the alkali resistance of a vinyl neodecanoate acrylic latex can also be improved by the copolymerization of VV10. As can be seen from Figure 5, dry VV10-based latex films immersed for two weeks in a 2% NaOH solution remain almost unchanged. The alkali extractables from a latex clear film of the VeoVa-based terpolymer can be as low as the one of an all-acrylic or styrene-acrylic, and definitively better than a vinyl neodecanoate acrylic. Effect on Wet Scrub Resistance Vinyl neodecanoate acetate-rich polymers tend to soften and weaken considerably under the influence of water because vinyl acetate has a very hydrophilic characteristic. Hence, such systems may fail during wet cleaning or scrubbing. This is much less the case when the polymer contains a sufficient amount of hydrophobic monomer. VV10 performs better in this respect than other co-monomers for vinyl neodecanoate acetate. A series of vinyl neodecanoate acetate/VV10 binders with different VV10 content was formulated in a 60% PVC matte paint. The scrub resistance improved with increasing VV 10 content of the binder, as shown in Figure 6. Outdoor Durability Exterior paints first and foremost need to be resistant to the influence of the weather, such as fluctuations in temperature and humidity and to the effects of UV light. Equally important is that the paints resist exposure to alkali (e.g., from the substrate) and accommodate dimensional changes. VV10 latices, when properly formulated, have proven to be among the best performing under severe conditions. VV10, unlike other co-monomers for vinyl neodecanoate acetate, provides the hydrophobicity and hydrolytic stability required to resist degradation of the binder from exposure to alkaline substrates. Both vinyl neodecanoate acetate and VV10 impart good UV resistance. As can be seen in Figure 7, the VV10-based binders have much better outdoor durability than other vinyl neodecanoate acetate-based binders. Moreover, a VA/VV10 (70/30 m/m)-based paint equals or even outperforms the more expensive acrylic-based paints in erosion resistance and yellowing resistance. Also a vinyl neodecanoate acetate/VV10/BA (74/28/6) terpolymer-based paint performed very well in this 10-year exposure test. The paint with the styrene acrylic binder remained intact but severe yellowing was observed. The copolymerization of hydrophobic vinyl neodecanoate ester of branched neo-carboxylic acids significantly improves the performance of vinyl neodecanoate and acrylic binders. Manufacturing of vinyl neodecanoate acetate/VeoVa vinyl neodecanoate ester polymers is easy due to the favorable reactivity characteristics of the VeoVa monomer and vinyl neodecanoate acetate. Incorporating the highly branched structure enhances the alkaline and water resistance of the vinyl neodecanoate copolymers. The resulting paints will offer a high scrub resistance combined with excellent weathering resistance. Combining VeoVa monomers with acrylate monomers offers an additional tool to formulate a diversity of very versatile polymers for use in coating and adhesive applications. The upgraded acrylics perform very well on even the most demanding substrates such as metal, wood and even plastics.
Vinylene Carbonate
ethenyl 7,7-dimethyloctanoate; Neodecanoic acid vinyl ester; Neodecanoic acid, ethenyl ester cas no : 51000-52-3
Vinylpyrrolidone-vinyl acetate copolymer
vitamin B6; vitaminb6; PYRIDOXINE, N° CAS : 65-23-6 / 8059-24-3 ; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol; Vitamine B6. Piridoxina [Spanish]; Pirivitol ; Pyridoxine ; Pyridoxinum [Latin]; Pyridoxol; Vitamin B6 ;VITAMIN B6 COMPLEXAutres langues : Vitamin B6, Vitamina B6. Nom INCI : PYRIDOXINE. Nom chimique : 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-; vitamine B6. N° EINECS/ELINCS : 200-603-0 / 232-503-8. Ses fonctions (INCI). Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance. Agent d'entretien de la peau : Maintient la peau en bon état. (5-Hydroxy-6-methylpyridine-3,4-diyl)dimethanol; 200-603-0 [EINECS]; 2216; 232-503-8 [EINECS]; 2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine; 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]; 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl- [ACD/Index Name]; 3-hydroxy-2-Picoline-4,5-dimethanol; 3-Hydroxy-4,5-dimethylol-a-picoline; 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol [ACD/IUPAC Name]; 4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol [German] [ACD/IUPAC Name]; 4,5-Bis(hydroxyméthyl)-2-méthyl-3-pyridinol [French] [ACD/IUPAC Name]; 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol; 5-Hydroxy-6-methyl-3,4-pyridinedimethanol; 65-23-6 [RN]; Bezatin ; KV2JZ1BI6Z; MFCD00006335 [MDL number]; Piridoxina [Spanish]; Pirivitol ; Pyridoxine ;Pyridoxinum [Latin]; Pyridoxol; Vitamin B6 ; VITAMIN B6 COMPLEX; Piridossina; 139854 [Beilstein]; 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine; 2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine; 2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]; 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine; 2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine 2-methyl-4,5-dimethylol-pyridin-3-ol; 3-Hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine; 3-hydroxy-4,5-dimethylol-α-picoline; 3-Hydroxy-4,5-dimethylol-α-picoline; 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol; 4,5-Bis-hydroxymethyl-2-methyl-pyridin-3-ol; Adermin; Adermine; Becilan; Becilan (Trade name); Beesix; Beesix (Trade name); Beeswax; Benadon (Trade name); Bonasanit (Trade name); DB00165; Gravidox; Hexa-βlin ; Hexobion ; Hydoxin; hydroxin; MFCD00012807 [MDL number]; Naturetime B6; NCGC00164317-01; Nestrex; Oprea1_061614; Pharmakon1600-01505453 Piridossina [DCIT]; Piridoxina [INN-Spanish]; Prestwick2_000623; Prestwick3_000623; Pridoxine; PXL; Pyridoxin; Pyridoxine free base; Pyridoxinum [INN-Latin]; Pyridoxolum; Pyroxin; vitamin B6 vitaminb6; 吡哆醇 [Chinese]
Vinyltriacetoxysilane
Triacetoxy(vinyl)silane; (Triacetoxysilyl)ethylene, Vinyltriacetoxysilane cas no: 4130-08-9
Vinyltrimethoxysilane
(Trimethoxysilyl)ethylene, Ethenyltrimethoxysilane, Trimethoxy(vinyl)silane cas no: 2768-02-7
Vinyltris(2-methoxyethoxy)silane
Tris(2-methoxyethoxy)(vinyl)silane; Vinyltris(2-methoxyethoxy)silane cas no : 1067-53-4
Vinyltris(Methylethylketoxime)silane
VOS;Vinyltris(methylethy;Vinyl tris (MEKO) silane;Tri(2-butaneneoxime)cinylsilane;Tri(2-butaneneoxime)vinylsilane;Vinyltris(2-butanoneoxime)silane;Vinyl tri(butanone oximido) silane;vinyltri(methylethylketoxime)silane;Vinyltris(methyletylketoxime)silane;Vinyltris(methylethylketoxime)silan cas no : 2224-33-1
Vitamine B6 ( PYRIDOXINE)
CHOLECALCIFEROL, N° CAS : 67-97-0 - Vitamine D3, Nom INCI : CHOLECALCIFEROL, Ses fonctions (INCI), Agent d'entretien de la peau : Maintient la peau en bon état. Noms français : 9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3-BETA-OL; 9,10-SECOCHOLESTA-5,7,10(19)-TRIEN-3-OL, (3.BETA.,5Z,7E)-; VITAMIN D3; VITAMINE D3. Utilisation:Vitamine. Cholecalciferol (bg) ;cholekalciferol (cs); cholekalcyferol (pl); colecalciferol (da); colecalciferolo (it); colécalciférol (fr); D3-vitamin (hu); Kolekalciferol (hr); kolekalciferolis (lt); kolekalciferols (lv);Kolekalsiferoli (fi) kolekaltsiferool (et); 67-97-0 [RN]; calciol; Cholecalciferol (D3); Cholecalciferol (Vitamin D3); Cholecalciferol for system suitability; Cholecalciferol solution; Cholecalciferolum; colecalciferol [BAN]; colecalciferol [Spanish]; colécalciférol [French]; Colecalciferolum [Latin]; D3-Vicotrat ; FeraCol Granuvit D3 Micro-Dee NEO Dohyfral D3 Provitina Vi-De3 Videkhol Vigantol VITAMIN D Vitamin D3 Vitamin D3 solution VS2900000 колекальциферол [Russian] كوليكالسيفيرول [Arabic] (+)-vitamin D3; (3??,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol; (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol; Activated 7-dehydrocholesterol; Calciol; CC; Colecalciferol; colecalciferolum; Oleovitamin D3; Vitamin D-3; Vitamin D3 (+)-vitamin D3; calciol; CC; Colecalciferol; Vitamin D3 1,2-Bis(tribromophenoxy)ethane 7-Dehydrocholesterol Arachitol Cholecalciferol D3 Cholecalciferol, USP Grade Cholecalciferol|Vitamin D3 Colecalciferolo colecalciferolum Colecalciferolum Colecalcipherol D014807 D3-Vigantol Delsterol Deparal Devaron dihydrocholesterol Duphafral D3 1000 Ebivit EINECS 200-673-2 EINECS 215-797-2 Micro-D oleovitamin D3 Optimal-D Optimal-D Optimal-D; Vigantol Prestwick3_000429 Quintox Rampage Ricketon Trivitan VD3 VidDe-3-hydrosol Vi-de-3-hydrosol Vigorsan Vitamin D 3 vitamin d-3 vitamin D4 vitamind3
VP/VA COPOLYMER
DESCRIPTION:
VP/VA Copolymer is a film forming ingredient that works well in both skin/hair care products and cosmetics.
VP/VA Copolymer forms a film on the surface to trap and retain moisture for longer durations.
VP/VA Copolymer is found primarily in most hair care products, mascaras, nail polishes and also some skin care products.
The full form of VP/VA Copolymer is vinylpyrrolidone/vinyl acetate copolymer, which appears as a white powder in its raw form.


CAS Number, 25086-89-9
European Community (EC) Number: 607-540-1
Chem/IUPAC Name:, Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone
COSING REF No:, 60160



SYNONYMS OF VP/VA COPOLYMER:
Copovidone,Kollidon VA64,poly(V-co-V-Ac),poly(vinyl pyrrolidone-co-vinyl acetate),poly(vinylpyrrolidone-co-vinyl-acetate),polyvidone-vinylacetate 64,PVP VA64,PVP-VA,PVPVA 64,25086-89-9,PVP-VA,Polectron 845,Luviskol VA 28I,Luviskol VA 37E,Luviskol VA 64,Kolima 10,Kolima 35,ethenyl acetate;1-ethenylpyrrolidin-2-one,Gantron S 860,Ganex E 535,GAF-S 630,Luviskol VA 281,Luviskol VA 28 I,Luviskol VA 37 E,I 535,I 635,I 735,S 630
,Copovidone (Technical Grade),Luviskol VA-64,SCHEMBL29127,vinylpyrrolidone/vinyl acetate,Vinyl Pyrrolidone/Vinyl Acetate,N-vinylpyrrolidone/vinyl acetate,1-vinylpyrrolidone vinyl acetate,FYUWIEKAVLOHSE-UHFFFAOYSA-N,BCP31918,NSC114023,NSC114024,NSC114025,NSC114026,AKOS015898247,NSC-114023,NSC-114024,NSC-114025,NSC-114026,1-ethenylpyrrolidin-2-one; ethenyl acetate,ethenyl ethanoate; 1-ethenylpyrrolidin-2-one,FT-0659810,50% in ethanol pound copolymer,3:7 pound(c),A817635,acetic acid ethenyl ester; 1-ethenyl-2-pyrrolidinone,733045-73-3





VP/VA Copolymer has good compatibility with many modifiers, plasticizers, spray propellants and other cosmetic ingredients.

VP/VA Copolymer is a synthetic vinyl polymer composed of vinyl acetate and vinylpyrrolidone.


VP/VA copolymer is a synthetic polymer, or large molecule, used in skin care and hair care preparations primarily as a film-forming agent.
This category of ingredients creates a coating over the area of application which helps reduce transepidermal water loss (TEWL) and creates a smooth feeling.
VP/VA copolymer is created through the combining of two smaller molecules, vinyl acetate and polyvinylpyrrolidone (PVP).

Hair care products commonly use this multi-industry ingredient to help fix hair into place, which is why it’s commonly incorporated into hair sprays.
Skin care and cosmetic products also use this ingredient, tapping into VP/VA copolymer’s ability to hinder TEWL and assist in the suspending and dispersing of ingredients (such as UV filters) in formulas.

Suppliers can provide this ingredient as both a powder (in 100% concentration) or as an alcohol-based solution (in 50% concentration).
In rinse off products, this copolymer is used in percentages between 0.07-44%, whereas in leave on preparations, it’s utilized in percentages ranging from 0.001-10%.



The VP / VA copolymer is a large molecule consisting of N-vinylpyrrolidone (PV) and vinyl acetate (VA) monomers.
This film-forming agent is mainly used in hair care, it helps the hair to maintain their style by preventing them from absorbing moisture.
When VP/VA copolymer dries, VP/VA copolymer forms a thin layer on the skin, hair or nails.
VP/VA copolymer is forbidden in organic.

A film-forming, hair fixative ingredient that leaves hair shiny.
VP/VA copolymer is a modified version of PVP.
Directly from a source: "Polyvinylpyrrolidone/vinyl acetate (PVP/VA) resins are linear, random copolymers produced by the free-radical polymerization of the monomers in ratios varying from 70/30 to 30/70 vinyl acetate to vinylpyrrolidone."
Scientifically speaking, VP/VA copolymer is: acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone.


VP/VA Copolymer is a big polymer (created from repeating subunits) molecule that works as a film former and hair fixative agent.
VP/VA Copolymer is a modified version of the first and classic hair fixative, PVP, that alternates the water-loving VP (Vinyl Pyrrolidone) units with water-hating VA (Vinyl Acetate) units to create a film that is less brittle and less sensitive to air humidity.


USES OF VP/VA COPOLYMER:

VP/VA Copolymer is Used in hair care like aerosol sprays, non-aerosol products, liquid hair setting products, gels and mousses.
VP/VA Copolymer Acts as a film-forming agent and hair fixative.
VP/VA Copolymer Possesses degreasing, good combing-out and washing-out properties.


VP/VA copolymer is a 60:40 linear, random copolymer of N-vinyl-2-pyrolidone (PVP) and vinyl acetate.
VP/VA copolymer acts as a tablet binder in denture cleanser tablets.

VP/VA Copolymer is a white powder.
VP/VA Copolymer offers strong & stiff hold, enhanced high humidity curl retention and good propellant compatibility.
VP/VA Copolymer is a film-forming agent used in the formulation of hair spray, gel, mousse, hair wax and shampoo.


VP/VA Copolymer is a white, free-flowing powder.
In cosmetics and personal care products, VP/VA Copolymer is used primarily in the formulation of hair care products but can also be found in skin and nail products.


VP/VA Copolymer helps hair hold its style by inhibiting the hair’s ability to absorb moisture.
VP/VA Copolymer dries to form a thin coating on the skin, hair or nails.
Usage: Add to water phase of formulas (usually no heating required).
Typical use level between 1-12%.
VP/VA Copolymer can be used in formulation of hair spray, gel, mousse, hair wax and shampoo.


VP/VA Copolymer has a number of benefits to offer in the world of cosmetics and personal care.
VP/VA Copolymer can mainly be found in hair care products, followed by cosmetics and a few skin care products.

Skin care:
VP/VA Copolymer is responsible for forming a thin layer on the skin that feels smooth to the touch and makes the surface look flawless.
VP/VA Copolymer also retains moisture on the skin and doesn't allow it to run dry for longer durations of time.

Hair care:
VP/VA Copolymer is mainly used in hair care products for hair setting.
This ingredient does not allow the shafts to absorb any further moisture and thus lose any styling done on them.
VP/VA Copolymer also forms a thin coat on hair that helps them retain its shape.

Decorative cosmetics:
VP/VA Copolymer is also added to cosmetic products like nail polish and mascara because it dries up to form a film that inhibits the surface from absorbing any moisture and thus keeps it styled impeccably.

ORIGIN OF VP/VA COPOLYMER:
VP/VA Copolymer is made by the monomers of vinylpyrrolidone and vinyl acetate.
VP/VA Copolymer appears as a white free-flowing powder and is the result of very small chemical compounds combining to form a large molecule.

WHAT DOES VP/VA COPOLYMER DO IN A FORMULATION?
• Film forming
• Hair fixing
• Moisturising



CHEMICAL AND PHYSICAL PROPERTIES OF VP/VA COPOLYMER:
Boiling Point, 217°C
Solubility, Soluble in water
Molecular Weight
197.23 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
197.10519334 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
197.10519334 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
46.6Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
14
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
186
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
2
Computed by PubChem
Compound Is Canonicalized
Yes


SAFETY INFORMATION ABOUT VP/VA COPOLYMER:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


VP-VA COPOLYMER PHARMA GRADE
VP/VA Copolymer Pharma Grade is a film forming ingredient that works well in both skin/hair care products and cosmetics.
VP/VA Copolymer Pharma Grade forms a film on the surface to trap and retain moisture for longer durations.
VP/VA Copolymer Pharma Grade is found primarily in most hair care products, mascaras, nail polishes and also some skin care products.

CAS: 25086-89-9
MF: C10H15NO3
MW: 197.23
EINECS: 200-001-8

Synonyms
Aceticacid,ethenylester,polymerwith1-ethenyl-2-pyrrolidinone;aceticacidethenylester,polymerwith1-ethenyl-2-pyrrolidinone;aceticacidethenylestercopolymerwith1-ethenyl-2-pyrrolidinone;aceticacidvinylester,polymerwith1-vinyl-2-pyrrolidinone;gantrons860;i535;i635;i735
;25086-89-9;PVP-VA;Polectron 845;Luviskol VA 28I;Luviskol VA 37E;Luviskol VA 64;Kolima 10;Kolima 35;ethenyl acetate;1-ethenylpyrrolidin-2-one;Gantron S 860;Ganex E 535;GAF-S 630;Luviskol VA 281;Luviskol VA 28 I;Luviskol VA 37 E;I 535;I 635;I 735;S 630;MFCD00134018;Copovidone (Technical Grade);Luviskol VA-64;SCHEMBL29127;vinylpyrrolidone/vinyl acetate;Vinyl Pyrrolidone/Vinyl Acetate;N-vinylpyrrolidone/vinyl acetate;1-vinylpyrrolidone vinyl acetate;FYUWIEKAVLOHSE-UHFFFAOYSA-N;BCP31918;NSC114023;NSC114024;NSC114025;NSC114026;AKOS015898247;NSC-114023;NSC-114024;NSC-114025;NSC-114026;1-ethenylpyrrolidin-2-one; ethenyl acetate;ethenyl ethanoate; 1-ethenylpyrrolidin-2-one;FT-0659810;A817635;acetic acid ethenyl ester; 1-ethenyl-2-pyrrolidinone;733045-73-3

VP/VA Copolymer Pharma Grade is a type of copolymer that is used in the pharmaceutical industry.
VP/VA Copolymer Pharma Grade is made from high-quality monomers and has low levels of impurities.
This makes VP/VA Copolymer Pharma Grade ideal for use in drugs and other medical products.
VP/VA Copolymer Pharma Grade has many advantages, including its ability to resist degradation and fouling, its low reactivity, and its compatibility with other chemicals.

VP/VA Copolymer Pharma Grade is made by the monomers of vinylpyrrolidone and vinyl acetate.
VP/VA Copolymer Pharma Grade appears as a white free-flowing powder and is the result of very small chemical compounds combining to form a large molecule.
The full form of VP/VA Copolymer Pharma Grade is vinylpyrrolidone/vinyl acetate copolymer, which appears as a white powder in its raw form.
VP/VA Copolymer Pharma Grade is a 60:40 linear, random copolymer of N-vinyl-2-pyrolidone (PVP) and vinyl acetate.
VP/VA Copolymer Pharma Grade acts as a tablet binder in denture cleanser tablets.

VP/VA Copolymer Pharma Gradeis a Water-Soluble Polymer that is used as a Viscosity Modifier or stabilizer.
VP/VA Copolymer Pharma Grade is important because it helps to thicken and stabilize products such as cosmetics, shampoos, and other personal care items.
VP/VA Copolymer Pharma Grade has several advantages over other types of polymers, including its ability to form films that are resistant to degradation and its ability to resist fouling by microorganisms.

VP/VA Copolymer Pharma Grade are top-quality materials designed to boost the performance and quality of your pharmaceutical formulations.
They are suitable for use in tablet coatings, binders, and film formers.
They contain Vinylpyrrolidone (VP) and Vinyl Acetate (VA), offering excellent adhesion, cohesion, water-resistance, and film-forming properties.
Produced to meet the highest pharmaceutical standards, they can improve stability, enhance drug release, and improve the appearance of your products.
Their worldwide availability guarantees that customers can access this superior product regardless of their geographical locations.

VP/VA Copolymer Pharma Grade produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.
VP/VA Copolymer Pharma Grade resins are linear, random copolymers produced by the free-radical polymerization of the monomers in diferrent ratios.
VP/VA Copolymer Pharma Grade are available as white powders or clear solutions in ethanol and water.
VP/VA Copolymer Pharma Grade are widely used as film formers because of their film flexibility, good adhesion, luster, water remoistenability and hardness.
These properties make VP/VA Copolymer Pharma Grade suitable for a variety of industrial, personal care and pharmaceutical products.

VP/VA Copolymer Pharma Grade with different rations of N-Vinylpyrrolidone to Vinyl Acetate,soluble in most organic solvents.
Which exists in powder,water solution and ethnol solution form.
VP/VA Copolymer Pharma Grade' aqueous solutions are non-ionic, neutralization not required, Resultant films are hard, glossy, and water-removable; Tunable viscosity, softening point and water sensitivity depending on VP/VA ratio; Good compatibility with many modifiers, plasticizers, spray propellants and other cosmetic ingredients,and the hydroscopicity decreases in proportion to the ration of Vinyl acetate.

VP/VA Copolymer Pharma Grade is a film former used primarily in hair care products, but also found in mascaras, nail polishes, and some skin care products, because of its ability to inhibit the hair (or lashes) from absorbing moisture; it dries and forms a thin barrier on hair, nails or skin.
When used in hair care products, VP/VA Copolymer Pharma Grade allows hair to hold a style longer by preventing moisture from entering the hair shaft.
VP/VA Copolymer Pharma Grade is also used to hold together the ingredients of a compressed tablet or cake and helps to distribute or to suspend an insoluble solid in a liquid.

VP/VA Copolymer Pharma Grade is a white or slightly yellowish, free-flowing powder with a faint characteristic odor and practically no taste.
VP/VA Copolymer Pharma Grade readily dissolves in all hydrophilic solvents.
Solutions of more than 10 % concentration can be prepared in water, ethanol, isopropanol, methylene chloride, glycerol and propylene glycol.
VP/VA Copolymer Pharma Grade is less soluble in ether, cyclic, aliphatic and alicyclic hydrocarbons.

VP/VA Copolymer Pharma Grade is a synthetic polymer, or large molecule, used in skin care and hair care preparations primarily as a film-forming agent.
This category of ingredients creates a coating over the area of application which helps reduce transepidermal water loss (TEWL) and creates a smooth feeling.
VP/VA Copolymer Pharma Grade is created through the combining of two smaller molecules, vinyl acetate and polyvinylpyrrolidone (PVP).
Hair care products commonly use this multi-industry ingredient to help fix hair into place, which is why VP/VA Copolymer Pharma Grade’s commonly incorporated into hair sprays.
Skin care and cosmetic products also use this ingredient, tapping into VP/VA Copolymer Pharma Grade’s ability to hinder TEWL and assist in the suspending and dispersing of ingredients (such as UV filters) in formulas.
Suppliers can provide VP/VA Copolymer Pharma Grade as both a powder (in 100% concentration) or as an alcohol-based solution (in 50% concentration).
In rinse off products, VP/VA Copolymer Pharma Grade is used in percentages between 0.07-44%, whereas in leave on preparations, it’s utilized in percentages ranging from 0.001-10%.

VP/VA Copolymer Pharma Grade Chemical Properties
Density: 1.27 g/mL at 25 °C(lit.)
Refractive index: 1.4300 to 1.4380
Fp: 72 °F
Solubility: Greater than 10% solubility in 1,4-butanediol, glycerol, butanol, chloroform, dichloromethane, ethanol (95%), glycerol, methanol, polyethylene glycol 400, propan-2-ol, propanol, propylene glycol, and water. Less than 1% solubility in cyclohexane, diethyl ether, liquid paraffin, and pentane.
Form: powder
Color: White
Stability: Stable. Combustible, especially in powdered form. Incompatible with strong oxidising agents, strong reducing agents.
InChI: InChI=1S/C6H9NO.C4H6O2/c1-2-7-5-3-4-6(7)8;1-3-6-4(2)5/h2H,1,3-5H2;3H,1H2,2H3
InChIKey: FYUWIEKAVLOHSE-UHFFFAOYSA-N
LogP: 0.370 (est)
EPA Substance Registry System: VP/VA Copolymer Pharma Grade (25086-89-9)

VP/VA Copolymer Pharma Grade is a white to yellowish-white amorphous powder.
VP/VA Copolymer Pharma Grade is typically spray-dried with a relatively fine particle size.
VP/VA Copolymer Pharma Grade has a slight odor and a faint taste.

Uses
VP/VA Copolymer Pharma Grade is a water-soluble polymer used to improve the uptake and drug loading of various pharmaceutical agents, including contraceptive patches.
VP/VA Copolymer Pharma Grade has a number of benefits to offer in the world of cosmetics and personal care.
It can mainly be found in hair care products, followed by cosmetics and a few skin care products.

Skin care: VP/VA Copolymer Pharma Grade is responsible for forming a thin layer on the skin that feels smooth to the touch and makes the surface look flawless.
VP/VA Copolymer Pharma Grade also retains moisture on the skin and doesn't allow it to run dry for longer durations of time.

Hair care: VP/VA Copolymer Pharma Grade is mainly used in hair care products for hair setting.
This ingredient does not allow the shafts to absorb any further moisture and thus lose any styling done on them.
VP/VA Copolymer Pharma Grade also forms a thin coat on hair that helps them retain its shape.

Decorative cosmetics: VP/VA Copolymer Pharma Grade is also added to cosmetic products like nail polish and mascara because it dries up to form a film that inhibits the surface from absorbing any moisture and thus keeps it styled impeccably.

Pharmaceutical Applications
VP/VA Copolymer Pharma Grade is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations.
In tableting, copovidone can be used as a binder for direct compression and as a binder in wet granulation.
VP/VA Copolymer Pharma Grade is often added to coating solutions as a film-forming agent.
VP/VA Copolymer Pharma Grade provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.

Production Methods
VP/VA Copolymer Pharma Grade is manufactured by free-radical polymerization of vinylpyrrolidone and vinyl acetate in a ratio of 6 : 4.
The synthesis is conducted in an organic solvent owing to the insolubility of vinyl acetate in water.
VULKACIT DM/C
VULKACIT DM/C Vulkacit DM/C Vulcanization is the conversion of a high-molecular material from the plastic to the elastic state. One of the key chemical reactions in this process is that of rubber with sulfur. Sulfur vulcanization, widely used in the rubber industry, requires the use of vulcanization accelerators such as Vulkacit DM/C. Used in tread, side walls , auto tubes and carcass Manufacture of antibiotics cephalosporin V belts conveyor belts, hoses , cables, Manufacture of textile auxiliaries Anticorrosion agent in boilers Technical moldings and extrudates in general, e.g. seals, hose, profiles, cable sheeting & insulation Synonyms Vulkacit DM/C 576 Vulkacit DM/C CZ/C CBS Vulkacit DM/C CZ/EGC CBS Vulkacit DM/C DM/C MBTS Vulkacit DM/CDM/MG-C MBTS Vulkacit DM/C I 53880-86-7 Vulkacit DM/C LDA ZDEC Vulkacit DM/C DZ/EGC Vulkacit DM/C LDB ZDBC Vulkacit DM/C LDB/C ZDBC Vulkacit DM/C MOZ/LG MBS Vulkacit DM/C Merkapto/C MBT Vulkacit DM/C Merkapto/MG-C MBT Vulkacit DM/C NZ/EGC TBBS Vulkacit DM/C P Extra N ZEPC Vulkacit DM/C Thiuram/C TMTD Vulkacit DM/C ZBEC ZBEC Vulkacit DM/C ZBEC/C ZBEC Vulkacit DM/C ZM ZMBT Vulkacit DM/C ZM2 ZMBT Vulkacit DM/C ZM-2W ZMBT Vulkacit DM/CZM-W ZMBT Vulkacit DM/C® Technical Data Sheets This page has links to all data sheets in MatWeb for the tradename Vulkacit DM/C®. We have several search tools, listed above, that give you more efficient methods to reach the information that you need. Vulkacit DM/C® has 19 material(s) in the MatWeb database. Back to Tradename List Lanxess Vulkacit DM/C® 576 Vulcanization Accelerator Lanxess Vulkacit DM/C® CZ/C Vulcanization Accelerator Lanxess Vulkacit DM/C® CZ-EG-C Vulcanization Accelerator Lanxess Vulkacit DM/C® DM/C Vulcanization Accelerator Lanxess Vulkacit DM/C® DM/MG-C Vulcanization Accelerator Lanxess Vulkacit DM/C® DM-PB/C Vulcanization Accelerator Lanxess Vulkacit DM/C® DZ/EG-C Vulcanization Accelerator Lanxess Vulkacit DM/C® F-C Vulcanization Accelerator Lanxess Vulkacit DM/C® I Vulcanization Accelerator Lanxess Vulkacit DM/C® LDA Vulcanization Accelerator Lanxess Vulkacit DM/C® Merkapto/C Vulcanization Accelerator Lanxess Vulkacit DM/C® Merkapto/MG-C Vulcanization Accelerator Lanxess Vulkacit DM/C® NZ/EG-C Vulcanization Accelerator Lanxess Vulkacit DM/C® Thiuram/C Vulcanization Accelerator Lanxess Vulkacit DM/C® ZBEC/C Vulcanization Accelerator Lanxess Vulkacit DM/C® ZM Vulcanization Accelerator Lanxess Vulkacit DM/C® ZM-2 Vulcanization Accelerator Lanxess Vulkacit DM/C® ZM-2W Vulcanization Accelerator Lanxess Vulkacit DM/C® ZM-W Vulcanization Accelerator Vulcanization is the conversion of a high molecular material from the plastic to the elastic state. One of the key chemical reactions in this process is that of rubber with sulfur. Sulfur vulcanization, widely used in the rubber industry, requires the use of vulcanization accelerators such as Vulkacit DM/C®. Vulcanization accelerators are not catalysts because they are part of the chemical reaction. The great variety of accelerators available is a result of their different influences on the vulcanization kinetics (scorch and cure time) and on physical properties such as tensile strength, elasticity or resistance to aging. In many cases, accelerators are combined to supply optimal processing and physical properties Vulkacit DM/C Merkapto This document provides a brief description of Vulkacit DM/C Merkapto, its uses, and the potential hazards associated with short and long term exposure. Environmental impact information for accidental releases is included. This information is general in nature and is not intended as a replacement for the safety data sheet (SDS), product label and other safe handling literature. For additional information consult the LANXESS safety data sheet. Identification Product Name: Vulkacit DM/C Merkapto Chemical Name: 2-Mercaptobenzothiazole Synonym(s): 2(3H)-Benzothiazolethione 2-Benzothiazolethiol Benzothiazole-2-thiol MBT CAS Number: 149-30-4 Description Overview: Vulkacit DM/C Merkapto is a yellow solid at ambient temperatures. The chemical is sold by LANXESS in powder form with a mild, pungent odor. Uses: Vulkacit DM/C Merkapto is manufactured by LANXESS for use as a vulcanization accelerator in the production of tires and other rubber products. The chemical is also used as a mildewicide in the manufacture of textiles, paper sizings and water-based adhesives; and as a corrosion inhibitor in cutting oils and petroleum products. Properties: Melting Point: Product Safety Assessment: Vulkacit DM/C Merkapto Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for exposure exists during manufacture, at transloading facilities, during transfers to storage or staging areas and—in its application as a vulcanization accelerator in the production of rubber—during the charging of mixers. Employee Training Workers handling Vulkacit DM/C Merkapto are trained to implement proper handling procedures and to understand the potential health and physical hazards of this product. NOISH approved, airpurifying particulate respirators are recommended for product handlers. In addition, LANXESS recommends that workers wear goggles, long-sleeved shirts, long pants and gloves when handling Vulkacit DM/C Merkapto to minimize skin and eye contact. Organic vapor respirators and engineering or process controls may be necessary in operations where the chemical is heated to thermal decomposition. Consumer Exposure LANXESS Corporation does not sell this product to the general public. Rubber goods using Vulkacit DM/C Merkapto as an accelerator retain the substance in encapsulated form in the final product. Persons susceptible to allergic skin reactions may experience “tennis shoe” dermatitis as a result of direct skin contact with shoes, elastic waistbands and other products containing the chemical. Skin irritation is typically temporary. Short-Term Health Effects Short-term contact with Vulkacit DM/C Merkapto may cause mild skin or eye irritation. Inhalation of Vulkacit DM/C Merkapto dust may cause respiratory tract irritation, with symptoms of coughing and a sore throat. Susceptible individuals may experience an allergic reaction from direct skin contact, with symptoms of redness, itching, swelling and rash. Vulkacit DM/C Merkapto is not expected to be harmful if swallowed. Long-Term Health Effects Long-term or repeated contact with Vulkacit DM/C Merkapto may cause skin sensitization. Physical Hazards Vulkacit DM/C Merkapto is a stable, non-volatile solid at room temperature. Avoid contact with strong oxidizing agents. Large concentrations of Vulkacit DM/C Merkapto dust may be explosive. Exposure to heat, open flames and other potential sources of ignition should be avoided. Potential Environmental Impact Vulkacit DM/C Merkapto is not biodegradable but the chemical does break down into biodegradable substances with prolonged exposure to water and/or light. Vulkacit DM/C Merkapto may pose a potential danger to fish (slight toxicity), invertebrates (moderate to high toxicity) and aquatic plants (moderate to high toxicity) prior to degrading. Accumulation in the environment is not expected. Product Safety Assessment: Vulkacit DM/C Merkapto Last Revised: August 2015 Page 3 of 3 Conclusion Under normal conditions of anticipated use as described in this Product Safety Assessment, and if the recommended safe use and handling procedures are followed, Vulkacit DM/C Merkapto is not expected to pose a significant risk to human health or the environment. References International Chemical Safety Card, International Programme on Chemical Safety (IPCS) Safety Data Sheet (SDS), Vulkacit DM/C MERKAPTO, LANXESS Corporation 2016 38121000 Vulkacit DM/C CZ/EG-C (N-CYCLOHEXYL-2-BENZOTHIAZOLESULFENAMIDE) United States Nhava Sheva Sea KGS 18,000 3,551,718 197 2016 38121000 RUBBER CHEMICALS ACCELERATOR - Vulkacit DM/C NZ/EG-C(R732) Belgium Nhava Sheva Sea KGS 12,000 2,867,592 239 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER CHEMICALS - ACCELERATOR) Belgium Chennai Sea KGS 12,000 2,867,592 239 2016 38121000 Vulkacit DM/C NZ/EG-C (N-TERT BUTYL -2-BENZOTHIAZOLE SULPHANIDE) Belgium Cochin Sea KGS 12,000 2,867,592 239 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 24,000 5,980,978 249 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 7,000 1,741,871 249 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 5,000 1,244,194 249 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 4,500 1,119,774 249 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 3,000 746,516 249 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 6,000 1,493,033 249 2016 38121000 Vulkacit DM/C CZ/EG-C (N-CYCLOHEXYL-2-BENZOTHIAZOLESULFENAMIDE) United States Nhava Sheva Sea KGS 18,000 3,549,091 197 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 4,000 995,355 249 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 2,000 497,678 249 2016 38121000 RUBBER ACCELERATOR WF12 Vulkacit DM/C DPG POWDER FORM DIPHENYL GUANIDINE DPG China Pithampur KGS 8,000 1,883,024 235 2016 38121000 2-MERCAPTOBENZOTHIAZOLE (MBT)(Vulkacit DM/C MERKAPTO/MG Belgium Chennai Sea KGS 61,200 7,933,261 130 2016 38121000 2-MERCAPTOBENZOTHIAZOLE (MBT) Vulkacit DM/C MERKAPTO/MG Belgium Chennai Sea KGS 40,800 5,284,926 130 2016 38121000 RUBBER CHEMICALS ACCELERATOR - Vulkacit DM/C NZ/EG-C(R732) Belgium Nhava Sheva Sea KGS 1,700 405,641 239 2016 38121000 RUBBER CHEMICALS ACCELERATOR - Vulkacit DM/C NZ/EG-C(R732) Belgium Nhava Sheva Sea KGS 9,600 2,290,680 239 2016 38121000 RUBBER CHEMICALS ACCELERATOR - Vulkacit DM/C NZ/EG-C(R732) Belgium Nhava Sheva Sea KGS 700 167,029 239 2016 38121000 Vulkacit DM/C NZ/EG-C (RUBBER ACCELERATORS) Belgium Chennai Sea KGS 24,000 5,972,130 249 Vulkacit DM/C® Products & Applications - Overview Grade Name Description Vulkacit DM/C® CZ/C N-cyclohexyl-2-benzothiazolesulfenamide (CBS) Supply form: powder, low dust Specification Specification Vulkacit DM/C® CZ/EG-C N-cyclohexyl-2-benzothiazolesulfenamide (CBS) Supply form: granules, low dust Specification Specification Vulkacit DM/C® DM-PB/C di(benzothiazol-2-yl) disulfide (MBTS) Supply form: powder, low dust Specification Specification Vulkacit DM/C® DM/C di(benzothiazol-2-yl) disulfide (MBTS) Supply form: powder, low dust Specification Specification Vulkacit DM/C® DM/MG-C di(benzothiazol-2-yl) disulfide (MBTS) Supply form: microgranules, low dust Specification Specification Vulkacit DM/C® DZ/EG-C (Kallo, Belgium) benzothiazyl-2-cyclo-hexyl sulfenamide (DCBS) Supply form: granules, low dust Specification Specification Vulkacit DM/C® Merkapto/C 2-mercaptobenzothiazole (MBT) Supply form: powder, low dust Specification Specification Vulkacit DM/C® Merkapto/MG-C 2-mercaptobenzothiazole (MBT) Supply form: microgranules, low dust Specification Specification Vulkacit DM/C® NZ/EG-C N-tert-butyl-benzo-thiazyl sulfenamide (TBBS) Supply form: granules, low dust Specification Specification Vulkacit DM/C® ZM zinc-2-mercaptobenzothiazole (ZMBT) Supply form: powder Latex application areas: coagulated goods, foams, shoes, automotive - also acts as a sensitizing agent for foam compounds Specification Specification Vulkacit DM/C® ZM-2 zinc-2-mercaptobenzothiazole (ZMBT) Supply form: powder low MBT version of Vulkacit DM/C® ZM Specification Specification Vulkacit DM/C® ZM-W zinc-2-mercaptobenzothiazole (ZMBT) Supply form: powder wettable version of Vulkacit DM/C® ZM for latex Vulkacit DM/C CZ/EG-C This document provides a brief description of Vulkacit DM/C CZ/EG-C, its uses, and the potential hazards associated with short and long term exposure. Environmental impact information for accidental releases is included. This information is general in nature and is not intended as a replacement for the safety data sheet (SDS), product label and other safe handling literature. For additional information consult the LANXESS safety data sheet. Identification Product Name: Vulkacit DM/C CZ/EG-C Chemical Name: n-Cyclohexyl-2-benzothiazolesulfenamide coated with mineral oil Synonym(s): CBS 2-(Cyclohexylaminothio)benzothiazole Cyclohexyl benzothiazole sulfenamide CAS Number: 95-33-0 Description Overview: Vulkacit DM/C CZ/EG-C is a light gray solid in granule form at ambient temperatures. The product has a slight odor. Uses: Vulkacit DM/C CZ/EG-C is used as a vulcanization accelerator in the production of tires and other rubber products. Properties: Melting Point: Flash Point: Solubility in Water: > 208°F (98°C) 334.4°F (168°C) Slight Product Safety Assessment: Vulkacit DM/C CZ/EG-C Last Revised: August 2015 Page 2 of 3 Potential Human Health Effects Occupational Exposure Potential for exposure exists through inhalation, ingestion, skin or eye contact during cleaning, maintenance and repair work in facilities that manufacture Vulkacit DM/C CZ/EG-C; at transloading facilities, during transfers to storage or staging areas andóin its application as a vulcanization acceleratoróduring the charging of mixers. Employee Training Workers handling Vulkacit DM/C CZ/EG-C are trained to implement proper handling procedures and to understand the potential health and physical hazards of this product. A NIOSH approved airpurifying particulate respirator is recommended for operations where dust concentrations exceed appropriate standards/guidelines. In addition, LANXESS recommends that goggles, permeation resistant clothing, gloves and foot protection be worn when handling Vulkacit DM/C CZ/EG-C. Consumer Exposure LANXESS Corporation does not sell this product to the general public. Rubber products manufactured using Vulkacit DM/C CZ/EG-C as an accelerator may retain encapsulated n-cyclohexyl-2- benzothiazolesulfenamide and persons susceptible to allergic skin reactions may experience temporary skin irritation from direct contact with these products. Trace amounts of n-cyclohexyl-2- benzothiazolesulfenamide can leach from rubber goods manufactured using the chemical as an intermediate, and the chemical has been found in drinking water and other water sources. Short-Term Health Effects Short-term skin or eye contact with Vulkacit DM/C CZ/EG-C may cause mild irritation. Susceptible individuals may experience an allergic reaction from direct contact with symptoms of redness, itching, swelling or rash. Inhalation of Vulkacit DM/C CZ/EG-C dust may cause respiratory tract irritation with symptoms of coughing, sore throat and runny nose. Vulkacit DM/C CZ/EG-C is not expected to be harmful if swallowed, although abdominal pain, nausea, vomiting and diarrhea may occur. Long-Term Health Effects Repeated or prolonged overexposure may result in sensitization and may cause effects as noted under Short-Term Health Effects. Certain mineral oils have been identified as known or suspected human carcinogens as well as fertility damage. Physical Hazards Vulkacit DM/C CZ/EG-C is a stable, non-volatile solid at room temperature. Avoid contact with strong oxidizing agents. Large concentrations of dust may form explosive mixtures with air. Heating to decomposition may release carbon monoxide and other toxic gases. Exposure to heat, open flames and other potential sources of ignition should be avoided. Potential Environmental Impact Vulkacit DM/C CZ/EG-C is not biodegradable but it does break down into biodegradable substances with prolonged exposure to water or light. Vulkacit DM/C CZ/EG-C may pose a potential danger to fish (slight toxicity), invertebrates (moderate to high toxicity) and aquatic plants (moderate to high toxicity) prior to degrading. Accumulation in the environment is not expected. Product Safety Assessment: Vulkacit DM/C CZ/EG-C Last Revised: August 2015 Page 3 of 3 Conclusion Under normal conditions of anticipated use as described in this Product Safety Assessment, and if the recommended safe use and handling procedures are followed, Vulkacit DM/C CZ/EG-C is not expected to pose a significant risk to human health or the environment. References European Union Risk Assessment Report: n-Cyclohexylbenzothiazol-2-sulphenemide, European Commission Safety Data Sheet (SDS), Vulkacit DM/C CZ/EG-C, LANXESS Corporation Vulkacit DM/C 576 Vulkacit DM/C CZ/C CBS Vulkacit DM/C CZ/EGC CBS Vulkacit DM/C DM/C MBTS Vulkacit DM/CDM/MG-C MBTS Vulkacit DM/C I 53880-86-7 Vulkacit DM/C LDA ZDEC Vulkacit DM/C DZ/EGC Vulkacit DM/C LDB ZDBC Vulkacit DM/C LDB/C ZDBC Vulkacit DM/C MOZ/LG MBS Vulkacit DM/C Merkapto/C MBT Vulkacit DM/C Merkapto/MG-C MBT Vulkacit DM/C NZ/EGC TBBS Vulkacit DM/C P Extra N ZEPC Vulkacit DM/C Thiuram/C TMTD Vulkacit DM/C ZBEC ZBEC Vulkacit DM/C ZBEC/C ZBEC Vulkacit DM/C ZM ZMBT
VULKANOX BKF
cas no: 91082-88-1
VULVIC ACID
Vulvic acid is a white, powdery solid with a faint odor of bay oil or soap.
Vulvic acid, Reagent, also known as n-Dodecanoic acid, is a medium chain fatty acid that has a vague smell of soap and is a powder.


CAS Number: 143-07-7
EC Number: 205-582-1
MDL Number: MFCD00004440
Molecular formula: C10H18O4 / HOOC(CH2)8COOH



SYNONYMS:
Dodecanoic acid, n-Dodecanoic acid, Dodecylic acid, Dodecoic acid, Laurostearic acid, Vulvic acid, 1-Undecanecarboxylic acid, Duodecylic acid, C12:0 (Lipid numbers), Laurostearic acid, Laurates, NSC 5026, Vulvic acid, 1-Dodecanoic acid, Dodecanoates, Lauric acid, Dodecylic acid, 1-Undecanecarboxylic acid, FA12:0, n-Dodecanoic acid, lauric acid, n-dodecanoic acid, dodecylic acid, vulvic acid, laurostearic acid, dodecoic acid, duodecylic acid, 1-undecanecarboxylic acid, aliphat no. 4, neo-fat 12, Decanedioic acid, 1,8-Octanedicarboxylic acid, Decane-1,10-dioic acid, sebacic acid, DECANEDIOIC ACID, 111-20-6, 1,8-Octanedicarboxylic acid, 1,10-Decanedioic acid, Sebacic acids, Sebacinsaure, Decanedicarboxylic acid, n-Decanedioic acid, Acide sebacique, Sebacinsaeure, USAF HC-1, Ipomic acid, Seracic acid, Decanedioic acid, homopolymer, NSC 19492, UNII-97AN39ICTC, 1,8-dicarboxyoctane, 26776-29-4, NSC19492, 97AN39ICTC, octane-1,8-dicarboxylic acid, CHEBI:41865, NSC-19492, DSSTox_CID_6867, DSSTox_RID_78231, DSSTox_GSID_26867, SebacicAcid, CAS-111-20-6, CCRIS 2290, EINECS 203-845-5, BRN 1210591, n-Decanedioate, Iponic acid, AI3-09127, disodium-sebacate, 4-oxodecanedioate, MFCD00004440, 1,10-Decanedioate, Sebacic acid, 94%, Sebacic acid, 99%, Dicarboxylic acid C10, 1i8j, 1l6s, 1l6y, 1,8-Octanedicarboxylate, WLN: QV8VQ, SEBACIC ACID, EC 203-845-5, SCHEMBL3977, NCIOpen2_008624, SEBACIC ACID, 4-02-00-02078, SEBACIC ACID, CHEMBL1232164, DTXSID7026867, Sebacic acid, >=95.0% (GC), ZINC1531045, Tox21_201778, Tox21_303263, BBL011473, LMFA01170006, s5732, STL146585, AKOS000120056, CCG-266598, CS-W015503, DB07645, GS-6713, HY-W014787, NCGC00164361-01, NCGC00164361-02, NCGC00164361-03, NCGC00257150-01, NCGC00259327-01, BP-27864, NCI60_001628, DB-121158, FT-0696757, C08277, A894762, C10-120, C10-140, C10-180, C10-220, C10-260, C10-298, Q413454, Q-201703, Z1259273339, 301CFA7E-7155-4D51-BD2F-EB921428B436, 1,8-Octanedicarboxylic acid, Decanedioic acid, Octane-1,8-dicarboxylic acid, 1,10-Decanedioic Acid, 1,8-Octanedicarboxylic Acid, NSC 19492, NSC 97405, n-Decanedioic Acid, 1,10-Decanedioate, 1,10-Decanedioic acid, 1,8-Dicarboxyoctane, 1,8-Octanedicarboxylate, 1,8-Octanedicarboxylic acid, 4,7-Dioxosebacic acid, 4,7-dioxosebacic acid, 4-Oxodecanedioate, 4-oxodecanedioate, 4-Oxodecanedioic acid, 1,10-Decanedioic acid, 1,8-Dicarboxyoctane, Decanedioic acid, Sebacinsaeure, 1,10-Decanedioate, Decanedioate, Sebacate, 1,8-Octanedicarboxylate, 1,8-Octanedicarboxylic acid, 4,7-Dioxosebacic acid, 4-Oxodecanedioate, 4-Oxodecanedioic acid, Acide sebacique, Decanedicarboxylic acid, Dicarboxylic acid C10, Ipomic acid, N-Decanedioate, N-Decanedioic acid, Sebacic acids, Sebacinsaure, Seracic acid, Sebacic acid, aluminum salt, Sebacic acid, monocadmium salt, Sebacic acid, sodium salt, DECANEDIOIC ACID, sebacic, USAF hc-1, acidesebacique, SEBACIC ACID pure, n-Decanedioic acid, 1,10-Decanedioic acid, Decanedicarboxylic acid, sebacate (decanedioate), 1,8-OCTANEDICARBOXYLIC ACID, 1,10-Decanedioate, 1,10-Decanedioic acid, 1,8-Octanedicarboxylate, 1,8-Octanedicarboxylic acid, 4,7-Dioxosebacic acid, 4-Oxodecanedioate, 4-Oxodecanedioic acid, Acide sebacique, Decanedicarboxylic acid, Decanedioate, 1,8-Octanedicarboxylic acid, 1,10-Decanedioic acid, n-Decanedioic acid, 4-Oxodecanedioate, 1,8-Dicarboxyoctane, Octane-1,8-dicarboxylic acid, Sebacic acid, Ipomic acid, Seracic acid, lauric acid, DODECANOIC ACID, 143-07-7, n-Dodecanoic acid, Dodecylic acid, Laurostearic acid, Vulvic acid, Dodecoic acid, Duodecylic acid, 1-Undecanecarboxylic acid, Aliphat No. 4, Ninol AA62 Extra, Wecoline 1295, Hydrofol acid 1255, Hydrofol acid 1295, Duodecyclic acid, Hystrene 9512, Univol U-314, Lauric acid, pure, Dodecylcarboxylate, Lauric acid (natural), Laurinsaeure, Undecane-1-carboxylic acid, ABL, NSC-5026, FEMA No. 2614, laurate, C-1297, Philacid 1200, CCRIS 669, C12:0, Emery 651, Lunac L 70, CHEBI:30805, HSDB 6814, EINECS 205-582-1, UNII-1160N9NU9U, BRN 1099477, n-Dodecanoate, Kortacid 1299, Dodecanoic Acid Anion, DTXSID5021590, Prifrac 2920, AI3-00112, Lunac L 98, Univol U 314, Prifac 2920, 1160N9NU9U, MFCD00002736, DAO, DTXCID801590, CH3-[CH2]10-COOH, NSC5026, EC 205-582-1, dodecylate, laurostearate, vulvate, 4-02-00-01082 (Beilstein Handbook Reference), DODECANOIC ACID (LAURIC ACID), 1-undecanecarboxylate, LAURIC ACID (USP-RS), LAURIC ACID [USP-RS], CH3-(CH2)10-COOH, 8000-62-2, CAS-143-07-7, SMR001253907, laurinsaure, dodecanic acid, Nuvail, lauric-acid, Acide Laurique, 3uil, Lauric acid (NF), DODECANOICACID, fatty acid 12:0, Lauric Acid, Reagent, Nissan NAA 122, Emery 650, Dodecanoic acid, 98%, Dodecanoic acid, 99%, Guaranteed Reagent,99%, Dodecanoic (Lauric) acid, LAURIC ACID [MI], bmse000509, LAURIC ACID [FCC], LAURIC ACID [FHFI], SCHEMBL5895, NCIOpen2_009480, MLS002177807, MLS002415737, WLN: QV11, Dodecanoic acid (lauric acid), LAURIC ACID [WHO-DD], Dodecanoic acid, >=99.5%, Edenor C 1298-100, DODECANOIC ACID [HSDB], CHEMBL108766, GTPL5534, NAA 122, NAA 312, HMS2268C14, HMS3649N06, HY-Y0366, STR08039, Dodecanoic acid, analytical standard, Lauric acid, >=98%, FCC, FG, Tox21_202149, Tox21_303010, BDBM50180948, LMFA01010012, s4726, STL281860, AKOS000277433, CCG-266587, DB03017, FA 12:0, HYDROFOL ACID 1255 OR 1295, NCGC00090919-01, NCGC00090919-02, NCGC00090919-03, NCGC00256486-01, NCGC00259698-01, AC-16451, BP-27913, DA-64879, Dodecanoic acid, >=99% (GC/titration), LAU, Dodecanoic acid, purum, >=96.0% (GC), Lauric acid, natural, >=98%, FCC, FG, CS-0015078, L0011, NS00008441, EN300-19951, C02679, D10714, A808010, LAURIC ACID (CONSTITUENT OF SAW PALMETTO), Q422627, SR-01000838338, J-007739, SR-01000838338-3, BRD-K67375056-001-07-9, F0001-0507, LAURIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC], Z104476194, 76C2A2EB-E8BA-40A6-8032-40A98625ED7B, Lauric acid, European Pharmacopoeia (EP) Reference Standard, Lauric acid, United States Pharmacopeia (USP) Reference Standard, Lauric Acid, Pharmaceutical Secondary Standard; Certified Reference Material, 203714-07-2, 7632-48-6, InChI=1/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14, 1-Undecanecarboxylate, 1-Undecanecarboxylic acid, ABL, Acide Laurique, C12 fatty acid, C12:0, Coconut oil fatty acids, DAO, Dodecanoate, dodecanoic acid, dodecoate, Dodecoic acid, Dodecylate, dodecylcarboxylate, Dodecylic acid, duodecyclate, Duodecyclic acid, duodecylate, Duodecylic acid, LAP, LAU, Laurate, Lauric acid, Laurinsaeure, Laurostearate, Laurostearic acid, MYR, n-Dodecanoate, n-Dodecanoic acid, Sorbitan laurate, Sorbitan monolaurate (NF), undecane-1-carboxylate, Undecane-1-carboxylic acid, Vulvate, Vulvic acid, CH3-[CH2]10-COOH, Dodecylcarboxylic acid, Laate, Laic acid, Aliphat no. 4, Edenor C 1298-100, Emery 651, Hystrene 9512, Kortacid 1299, Lunac L 70, Lunac L 98, Neo-fat 12, Neo-fat 12-43, Nissan naa 122, Philacid 1200, Prifac 2920, Univol u 314, 1-Dodecanoic acid, FA(12:0), 1-Undecanecarboxylic acid, ABL, Aliphat no. 4, C12 fatty acid, Coconut oil fatty acids, Dodecanoate, Dodecanoic (lauric) acid, Dodecanoic acid (lauric acid), Dodecoic acid, Dodecylcarboxylate, Dodecylic acid, Duodecyclic acid, Duodecylic acid, Emery 650, Lauric acid, Lauric acid, pure, Laurinsaeure, Laurostearic acid, Lunac L 70, n-Dodecanoic Acid, N-Dodecanoate, Neo-fat 12, Ninol aa62 extra, Undecane-1-carboxylic acid, Univol U 314, Univol U-314, Vulvic acid, AI3-00112, BRN 1099477, C-1297, CCRIS 669, EINECS 205-582-1, FEMA NO. 2614, HSDB 6814, HYDROFOL ACID 1255, HYDROFOL ACID 1295, HYSTRENE 9512, NEO-FAT 12-43, PHILACID 1200, PRIFRAC 2920, WECOLINE 1295, 1-Undecanecarboxylic acid, ABL, AC-16451, AC1L1GY2, AC1Q5W8C, AKOS000277433, Aliphat No. 4, CH3-[CH2]10-COOH, Coconut oil fatty acids, DAO, DODECANOIC ACID, DODECANOIC ACID (LAURIC ACID), Dodecanoate, Dodecanoic (Lauric) acid, Dodecanoic acid (lauric acid), Dodecanoic acid(Lauric acid), Dodecoic acid, Dodecylcarboxylate, Dodecylic acid, Duodecyclic acid, Duodecylic acid, Emery 650, Hydrofol acid 1255, Hydrofol acid 1295, Hystrene 9512, I04-1205, L-ALFA-LYSOPHOSPHATIDYLCHOLINE, LAUROYL, L0011, LAP, LAU, Lauric acid, pure, Laurinsaeure, Laurostearic acid, Lunac L 70, Neo-fat 12, Neo-fat 12-43, Ninol AA62 Extra, Philacid 1200, Prifrac 2920, SMR001253907, ST023796, Undecane-1-carboxylic acid, Univol U-314, Vulvic acid, Wecoline 1295, [2-((1-OXODODECANOXY-(2-HYDROXY-3-PROPANYL))-PHOSPHONATE-OXY)-ETHYL]-TRIMETHYLAMMONIUM, n-Dodecanoate, n-Dodecanoic acid, nchembio.364-comp10, Dodecanoic acid, n-Dodecanoic acid, Neo-fat 12, Aliphat no. 4, Abl, Dodecylic acid, Lauric acid, Laurostearic acid, Neo-fat 12-43, Ninol aa62 extra, Univol u-314, Vulvic acid, 1-Undecanecarboxylic acid, Duodecylic acid, C-1297, Coconut oil fatty acids, Hydrofol acid 1255, Hydrofol acid 1295, Wecoline 1295, Dodecoic acid, Hystrene 9512, Lunac L 70, Duodecyclic acid, Emery 650, n-Dodecanoate, Philacid 1200, Prifrac 2920, Undecane-1-carboxylic acid, C-1297, dodecanoic acid, dodecoic acid, duodecylic acid, ndodecanoic acid, Hydrofol acid 1255, Hydrofol acid 1295, Hystrene 9512, laurostearic acid, Neo-fat 12, Neo-fat 12-43, Ninol AA62 Extra, 1-undecanecarboxylic acid, vulvic acid, Wecoline 1295, Dodecoic acid, Duodecyclic acid, Edenor C 1298-100, Emery 650, Hydrofol acid 1295, Hystrene 9512, Kortacid 1299, Laurostearate, Lunac L 70, Lunac L 98, Neo-fat 12, Ninol AA62 extra, Nissan naa 122, Philacid 1200, Prifac 2920, Prifrac 2920, Univol U 314, Vulvate, Vulvic acid, Wecoline 1295, 1-Undecanecarboxylate, 1-Undecanecarboxylic acid, Dodecylate, Dodecylcarboxylate, Dodecylic acid, Duodecylic acid, Laurostearic acid, n-Dodecanoic acid, Undecane-1-carboxylic acid, LAP, LAU, DAO, lauric acid, n-dodecanoic acid, dodecylic acid, vulvic acid, laurostearic acid, dodecoic acid, duodecylic acid, 1-undecanecarboxylic acid, aliphat no. 4, neo-fat 12, 143-07-7, 205-582-1, 1-UNDECANECARBOXYLIC ACID, DODECANOIC ACID, DODECANOIC ACID [HSDB], DODECOIC ACID, FEMA NO. 2614, LAURATE, LAURIC ACID (CONSTITUENT OF SAW PALMETTO) [DSC], LAURIC ACID [FCC], LAURIC ACID [FHFI], LAURIC ACID [MI], LAURIC ACID [USP-RS], LAURIC ACID [WHO-DD], LAUROSTEARIC ACID, N-DODECANOIC ACID, NSC-5026, Dodecanoic acid, Lauric acid, Laurostearic acid, 1-Undecanecarboxylic acid, ABL, Aliphat No. 4, Univol U 314, Dodecylic acid, Vulvic acid, Neo-Fat 12-43, n-Dodecanoic acid, Neo-Fat 12, Lunac L 70, Emery 651, Prifac 2920, Nissan NAA 122, Lunac L 98, Hystrene 9512, NAA 312, Kortacid 1299, Philacid 1200, Edenor C 1298-100, NSC 5026, NAA 122, Prifac 2922, Edenor C 12, Prifrac 2920, ContraZeck, 1-Dodecanoic acid, Imex C 1299, Palmac 98-12, Edenor 12/98-100, Palmera B 1231, Edenor C 12-98-100, Lasacid FC 12, Laurates, Dodecanoates, Palmae 99-12, D 97385, Edenor C12-99, Coconut Hard 34, Coconut Hard 42, Radiacid 0624, NS 6, 7632-48-6, 8000-62-2, 8045-27-0, 203714-07-2, 55621-34-6, DODECANOIC ACID, C12, Emery651, Vulvic acid, FEMA 2614, lauric acid, pure, N-DODECANOIC ACID, LAUROSTEARIC ACID, Lauric acid 98-101 % (acidimetric), Fatty acid methyl ester sulfonate (MES), Dodecanoic D23 Acid, Dodecanoic Acid-d23,1-Dodecanoic Acid-d23, 1-Undecanecarboxylic Acid-d23, ABL-d23, Aliphat No. 4-d23, ContraZeck-d23, Dodecylic Acid-d23, Edenor C 12-d23,Edenor C 1298-100-d23, Emery 651-d23, Hystrene 9512-d23, Imex C 1299-d23, Kortacid 1299-d23, Laurostearic Acid-d23, Lunac L 70-d23, Lunac L 98-d23, NAA 122-d23, NAA 312-d23, NSC 5026-d23, Neo-Fat 12-d23, Neo-Fat 12-43-d23, Nissan NAA 122-d23, Philacid 1200-d23, Prifac 2920-d23, Prifac 2922-d23, Prifrac 2920-d23, Univol U 314-d23, Vulvic Acid-d23, n-Dodecanoic Acid-d23, Dodecanoate, Coconut Oil Fatty Acids, Laurostearic Acid, N-Dodecanoic Acid, C12 Fatty Acid, Duodecyclic Acid, Vulvic Acid, Dodecanoic Acid (Lauric Acid), Duodecylic Acid, N-Dodecanoate, Dodecanoic (Lauric) Acid, Laurinsaeure, Lauric Acid, Pure, Lauric Acid (Natural), Dodecylcarboxylate, Abl, Dao, Lap, Lau, Myr



Vulvic acid is a saturated fatty acid with the structural formula CH3(CH2)10COOH .
Vulvic acid is the main acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
Vulvic acid is also found in human milk(5.8% of total fat), cows milk(2.2%), and goat milk(4.5%).


Vulvic acid is a white, powdery solid with a faint odor of bay oil or soap.
Vulvic acid, Reagent, also known as Vulvic acid, is a medium chain fatty acid that has a vague smell of soap and is a powder.
Vulvic acid is found naturally in human breast milk as well as cow's and goat's milk.


Vulvic acid's reagent grade means this is the highest quality commercially available for this chemical and that the American Chemical Society has not officially set any specifications for this material.
Vulvic acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.


Vulvic acid is a solid at room temperature but melts easily in boiling water, so liquid Vulvic acid can be treated with various solutes and used to determine their molecular masses.
Vulvic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids.


Vulvic acid is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Vulvic acid are known as laurates.
Vulvic acid is a saturated fatty acid with a terminal carboxylic acid.


The terminal carboxylic acid, Vulvic acid, can react with primary amine groups in the presence of activators such as HATU.
Vulvic acid is a carbon 13 labeled form of a saturated fatty acid found in coconut milk, coconut oil, laurel oil, and palm kernel oil, as well as in human breast milk and other animal milks.


Vulvic acid is a proton pump inhibitor potentially for the treatment of helicobacter pylori infections.
In vitro experiments have suggested that some fatty acids including Vulvic acid could be a useful component in a treatment for acne, but no clinical trials have yet been conducted to evaluate this potential benefit in humans.


Vulvic acid increases total serum cholesterol more than many other fatty acids.
But most of the increase is attributable to an increase in high-density lipoprotein (HDL) (the "good" blood cholesterol).
As a result, Vulvic acid has been characterized as having "a more favorable effect on total HDL cholesterol than any other fatty acid, either saturated or unsaturated.


Vulvic acid, identified by CAS number 143-07-7, is a saturated medium-chain fatty acid with a 12-carbon atom backbone, prominently known for its role in the manufacturing of soaps, detergents, and cosmetics.
As a fundamental component, Vulvic acid is celebrated for its surfactant properties, which enable the production of a rich lather in cleansing products.


In research, Vulvic acid is extensively used to study lipid behavior in various systems due to its amphiphilic nature, which allows it to assemble into micelles and other nanostructures in aqueous solutions.
These studies are crucial for advancing the fields of material science and nanotechnology, particularly in the development of delivery systems and the enhancement of product formulations.


Additionally, Vulvic acid is employed in food science research where it serves as a model to understand the digestion and metabolism of medium-chain fatty acids.
Vulvic acid's antimicrobial properties are also examined in terms of how they can be leveraged in non-medical applications, such as in food preservation and safety, where reducing microbial growth is essential.


Moreover, Vulvic acid′s role in industrial applications extends to its use as a raw material in the synthesis of various chemical derivatives, including esters used in flavorings and fragrances, showcasing its versatility and importance in both scientific research and industrial applications.
Vulvic acid is a saturated medium-chain fatty acid with a 12-carbon backbone.


Vulvic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Vulvic acid, C12H24O2, also known as Vulvic acid, is a saturated fatty acid with a 12-carbon atom chain.
The powdery, white crystalline acid, Vulvic acid, has a slight odor of oil of bay and occurs naturally in various plant and animal fats and oils.


Vulvic acid is a major component of coconut oil and palm kernel oil.
Vulvic acid, CAS 143-07-7, chemical formula C12H24O2, is produced as a white crystalline powder, has a slight odor of bay oil, and is soluble in water, alcohols, phenyls, haloalkanes, and acetates.


Vulvic acid is non-toxic, safe to handle, inexpensive, and has a long shelf life.
Vulvic acid is a saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids.
Vulvic acid is a white, powdery solid with a faint odor of bay oil or soap.


Vulvic acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Vulvic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.


Vulvic acid is a potentially toxic compound.
Vulvic acid has the chemical formula C12H24O2.
Vulvic acid appears as a white crystalline solid with a characteristic odor like oil of bay.


Vulvic acid is insoluble in Water and soluble in Ether, Chloroform, and Alcohol.
Vulvic acid is found naturally in some plant and animal fats and is a key component of coconut oil.
Vulvic acid is synthetically prepared by the fractional distillation of other acids of mixed coconut.


Vulvic acid is a white solid with a slight odor of bay oil.
Vulvic acid is a straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.


Vulvic acid has a role as a plant metabolite, an antibacterial agent and an algal metabolite.
Vulvic acid is a straight-chain saturated fatty acid and a medium-chain fatty acid.
Vulvic acid is a conjugate acid of a dodecanoate.


Vulvic acid derives from a hydride of a dodecane.
Vulvic acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Vulvic acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.


Vulvic acid is a metabolite found in or produced by Escherichia coli.
Vulvic acid is a natural product found in Ipomoea leptophylla, Arisaema tortuosum, and other organisms with data available.
Vulvic acid is a saturated medium-chain fatty acid with a 12-carbon backbone.


Vulvic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Vulvic acid is the main fatty acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
Vulvic acid is a white, powdery solid with a faint odor of bay oil.


Vulvic acid, although slightly irritating to mucous membranes, has a very low toxicity and so is used in many soaps and shampoos.
Vulvic acid is a metabolite found in or produced by Saccharomyces cerevisiae.
Vulvic acid is a medium-chain saturated fatty acid.


Vulvic acid is found in many vegetable fats and in coconut and palm kernel oils.
Vulvic acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.


Vulvic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids.
Vulvic acid is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Vulvic acid are known as laurates.


Vulvic acid is a precursor to dilauroyl peroxide, a common initiator of polymerizations.
Vulvic acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.


Vulvic acid, also known as dodecanoate or lauric acid, belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.
Vulvic acid is a very hydrophobic molecule, practically insoluble (in water), and relatively neutral.


Vulvic acid is the main fatty acid in coconut oil and in palm kernel oil, and is believed to have antimicrobial properties.
Vulvic acid is a white, powdery solid with a faint odour of bay oil.
Vulvic acid, although slightly irritating to mucous membranes, has a very low toxicity and so is used in many soaps and shampoos.


Vulvic acid is a fatty acid that has been shown to inhibit the growth of bacteria.
Vulvic acid inhibits bacterial growth by binding to the active site of the enzyme dihydrolipoamide acetyltransferase, which catalyzes the conversion of dihydrolipoamide and acetyl-CoA to succinyl-CoA and acetoacetyl-CoA.


Vulvic acid also binds to dinucleotide phosphate, which is involved in regulation of phase transition temperature and biological samples.
Vulvic acid has also been shown to act as an active inhibitor of fatty acid synthase, an enzyme that catalyzes the synthesis of fatty acids from acetyl-coenzyme A (acetyl-CoA).


This process is essential for bacterial growth.
Vulvic acid has synergistic effects with other antibiotics such as ampicillin, erythromycin, and tetracycline.
Vulvic acid is a saturated medium-chain fatty acid with a 12-carbon backbone.


Vulvic acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Vulvic acid is a medium-length long-chain fatty acid, or lipid, that makes up about half of the fatty acids within coconut oil.
Vulvic acid’s a powerful substance that is sometimes extracted from the coconut for use in developing monolaurin.


Monolaurin is an antimicrobial agent that is able to fight bacteria, viruses, yeasts, and other pathogens.
Because you can’t ingest Vulvic acid alone (it’s irritating and not found alone in nature), you’re most likely to get it in the form of coconut oil or from fresh coconuts.


Though coconut oil is being studied at a breakneck pace, much of the research doesn’t pinpoint what in the oil is responsible for its reported benefits.
Because coconut oil contains much more than just Vulvic acid, it would be a stretch to credit it with all of the coconut oil benefits.
Still, a 2015 analysis suggests that many of the benefits tied to coconut oil are directly linked to Vulvic acid.


Among the benefits, they suggest Vulvic acid could aid weight loss and even protect against Alzheimer’s disease.
Its effects on blood cholesterol levels still need to be clarified.
This research suggests that the benefits of Vulvic acid are due to how the body uses it.


The majority of Vulvic acid is sent directly to the liver, where it’s converted to energy rather than stored as fat.
When compared with other saturated fats, Vulvic acid contributes the least to fat storage.
Vulvic acid is a saturated fatty acid with a 12-carbon atom chain, thus having many properties of medium-chain fatty acids.


Vulvic acid is a bright white, powdery solid with a faint odor of bay oil or soap.
The salts and esters of Vulvic acid are known as laurates.
Like many other fatty acids, Vulvic acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle.


Vulvic acid is mainly used for the production of soaps and cosmetics.
For these purposes, Vulvic acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.


These precursors give mixtures of sodium laurate and other soaps. Vulvic acid occurs as a white crystalline powder
Vulvic acid is a saturated fatty acid with a 12-carbon atom chain used in industrial cleaners, lubricants, soaps, surfactants, agricultural additives, coatings, food additives, textile additives.


Vulvic acid, the saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids, is a white, powdery solid with a faint odor of bay oil or soap.
Vulvic acid, as a component of triglycerides, comprises about half of the fatty acid content in coconut oil, laurel oil, and in palm kernel oil.


Otherwise Vulvic acid is relatively uncommon.
Vulvic acid increases total serum cholesterol the most of any fatty acid.
But most of the increase is attributable to an increase in high-density lipoprotein (HDL) (the "good" blood cholesterol).


As a result, Vulvic acid has been characterized as having "a more favorable effect on total:HDL cholesterol than any other fatty acid, either saturated or unsaturated."
In general, a lower total/HDL serum cholesterol ratio correlates with a decrease in atherosclerotic risk.


For these purposes, Vulvic acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Vulvic acid is a saturated fatty acid with a 12-carbon atom chain, thus falling into the medium chain fatty acids.
Vulvic acid is a white crystalline carboxylic acid with a faint odor of bay oil or soap.


Vulvic acid has been found at high levels in coconut oil.
Vulvic acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.


Vulvic acid is a straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
Vulvic acid has a role as a plant metabolite, an antibacterial agent and an algal metabolite.


Vulvic acid is a straight-chain saturated fatty acid and a medium-chain fatty acid.
Vulvic acid is a conjugate acid of a dodecanoate.
Vulvic acid derives from a hydride of a dodecane.


Vulvic acid is a white crystalline carboxylic acid.
Vulvic acid is used as a plasticizer and for making detergents and soaps.
Vulvic acid's glycerides occur naturally in coconut and palm oils.


Vulvic acid is a white solid with a slight odor of bay oil.
Vulvic acid belongs to the class of organic compounds known as medium-chain fatty acids.
These are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms.


Vulvic acid is a white, powdery solid with a faint odour of mild fatty coconut bay oil or soap.
Vulvic acid is the main fatty acid in coconut oil (49%) and in palm kernel oil (47-50%), and is found in lesser amounts in wild nutmeg, human breast milk, cow’s milk, goat milk, watermelon seeds, plum and macadamia nut.


Vulvic acid, although slightly irritating to mucous membranes, has an extremely low toxicity, is inexpensive, has antimicrobial properties and so is used in many soaps and shampoos.
Vulvic acid is a weakly acidic compound.


Vulvic acid is reacted with sodium hydroxide to generate sodium laurate, which is soap.
Vulvic acid has been characterized as having "a more favorable effect on total HDL cholesterol than any other fatty acid either saturated or unsaturated"



USES and APPLICATIONS of VULVIC ACID:
Vulvic acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Vulvic acid is approved for use as a biocide in the EEA and/or Switzerland, for: repelling or attracting pests.


People also use Vulvic acid as medicine.
People use Vulvic acid for viral infections such as the flu, common cold, genital herpes, and many other conditions, but there is no good scientific evidence to support any use.


Vulvic acid is used in the following products: washing & cleaning products, coating products, fillers, putties, plasters, modelling clay, finger paints, polishes and waxes, air care products and plant protection products.
Other release to the environment of Vulvic acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Release to the environment of Vulvic acid can occur from industrial use: industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting) and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).


Other release to the environment of Vulvic acid is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).


Vulvic acid can be found in complex articles, with no release intended: vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).
Vulvic acid is also used as a food additive and an active component in a treatment for acne.


Vulvic acid can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture) and paper used for packaging (excluding food packaging).


Vulvic acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Vulvic acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Vulvic acid is also used as a food additive and an active component in a treatment for acne.


In addition to this, Vulvic acid is a substrate for acylation of certain proteins based on the murine studies.
Vulvic acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Vulvic acid is also used to measure the molar mass of an unknown substance through freezing point depression.


In addition to this, Vulvic acid is a substrate for acylation of certain proteins based on the murine studies.
Vulvic acid is used in the following products: washing & cleaning products, polishes and waxes, adhesives and sealants, cosmetics and personal care products and laboratory chemicals.


Vulvic acid is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Vulvic acid is used for the manufacture of: textile, leather or fur.


Release to the environment of Vulvic acid can occur from industrial use: formulation of mixtures and in processing aids at industrial sites.
Other release to the environment of Vulvic acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Vulvic acid is used in the following products: polymers, pH regulators and water treatment products, leather treatment products, coating products, fillers, putties, plasters, modelling clay, finger paints, inks and toners, cosmetics and personal care products, lubricants and greases and textile treatment products and dyes.


Release to the environment of Vulvic acid can occur from industrial use: formulation of mixtures and formulation in materials.
Vulvic acid is used in the following products: washing & cleaning products, leather treatment products, polymers, textile treatment products and dyes, pH regulators and water treatment products and lubricants and greases.


Vulvic acid is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Vulvic acid is used for the manufacture of: textile, leather or fur.


Release to the environment of Vulvic acid can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and as processing aid.
Release to the environment of Vulvic acid can occur from industrial use: manufacturing of the substance.


Vulvic acid is an inexpensive, non-toxic and safe to handle compound often used in laboratory investigations of melting-point depression.
Vulvic acid is a solid at room temperature but melts easily in boiling water, so liquid lauric acid can be treated with various solutes and used to determine their molecular masses.


In the laboratory, Vulvic acid may be used to investigate the molar mass of an unknown substance via the freezing-point depression.
The choice of Vulvic acid is convenient because the melting point of the pure compound is relatively high (43.8°C).
Its cryoscopic constant is 3.9°C•kg/mol.


By melting Vulvic acid with the unknown substance, allowing it to cool, and recording the temperature at which the mixture freezes, the molar mass of the unknown compound may be determined.
In industry, Vulvic acid is used as an intermediate and as a surface active agent.


Industrial applications of Vulvic acid and its derivatives include the fatty acid as a component of alkyd resins, wetting agents, a rubber accelerator and softener, detergents, and insecticides.
The consumer market uses Vulvic acid in the cleaning, furnishing, and production of personal care products.


In medicine, Vulvic acid is known to increase total serum cholesterol more than many of the other fatty acids.
Common Uses and Applications of Vulvic acid: Additive, Acidifiers, Chemical intermediate, Lubricant, Synthesis of substances, Industries, Chemical Production, Personal Care, and Laboratories.


Vulvic acid is mainly used in the manufacturing of soaps and other cosmetics.
In scientific laboratories, Vulvic acid is often used to investigate the molar mass of unknown substances via freezing-point depression.
In industry, Vulvic acid is used as an intermediate and as a surface active agent.


The consumer market uses Vulvic acid in the cleaning, furnishing, and production of personal care products.
In medicine, Vulvic acid is known to increase total serum cholesterol more than many of the other fatty acids.
Vulvic acid is mainly used in the manufacture and production of soaps and other cosmetics as well as scientific laboratory uses.


Vulvic acid is used as an intermediate and surface active agent in industry and in the manufacture of personal care products in the consumer market.
Vulvic acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Vulvic acid is also used to measure the molar mass of an unknown substance through freezing point depression.


Vulvic acid is also used as a food additive and an active component in a treatment for acne.
In addition to this, Vulvic acid is a substrate for acylation of certain proteins based on the murine studies.
Vulvic acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.


Vulvic acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Vulvic acid is also used as a food additive and an active component in a treatment for acne.
In addition to this, Vulvic acid is a substrate for acylation of certain proteins based on the murine studies.


Vulvic acid is used in the preparation of cosmetics, soaps, alkyd resins and wetting agents.
Vulvic acid is also used to measure the molar mass of an unknown substance through freezing point depression.
Vulvic acid is also used as a food additive and an active component in a treatment for acne.


In addition to this, Vulvic acid is a substrate for acylation of certain proteins based on the murine studies.
Vulvic acid is generally used to produce cosmetic products but is also used in the laboratory to obtain the molar mass of substances.
Vulvic acid, although slightly irritating to mucous membranes, has a very low toxicity and so is used in many soaps and shampoos.


Sodium lauryl sulfate is the most common Vulvic acid derived compound used for this purpose.
Because Vulvic acid has a non-polar hydrocarbon tail and a polar carboxylic acid head, it can interact with polar solvents (the most important being water) as well as fats, allowing water to dissolve fats.


This accounts for the abilities of shampoos to remove grease from hair.
Another use is to raise metabolism, believed to derive from Vulvic acid's activation of 20% of thyroidal hormones, otherwise which lay dormant.
This is supposed from Vulvic acid's release of enzymes in the intestinal tract which activate the thyroid.


This could account the metabolism-raising properties of coconut oil.
Because Vulvic acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle, it is often used in laboratory investigations of melting-point depression.


Vulvic acid is a solid at room temperature but melts easily in boiling water, so liquid it can be treated with various solutes and used to determine their molecular masses.
Vulvic acid is widely used in cosmetics and food products.


In pharmaceutical applications Vulvic acid has also been examined for use as an enhancer for topical penetration and transdermal absorption, rectal absorption, buccal delivery, and intestinal absorption.
Vulvic acid is also useful for stabilizing oil-in-water emulsions.


Vulvic acid has also been evaluated for use in aerosol formulations.
Vulvic acid is used in the production of personal care products via the salt sodium laurate.
Vulvic acid is also studied in metabolic and foodomics research for its potential impact on cardiovascular disease.


Vulvic acid has been used as a reagent to synthesize MnFe2O4 magnetic nanoparticles by seed mediated growth method.
Vulvic acid can undergo esterification with 2-ethylhexanol in the presence of sulfated zirconia catalyst to form 2-ethylhexanoldodecanoate, a biodiesel.
Like many other fatty acids, Vulvic acid is inexpensive, has a long shelf-life, is nontoxic, and is safe to handle.


Vulvic acid is used mainly for the production of soaps and cosmetics.
For these purposes, Vulvic acid is reacted with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.


These precursors give mixtures of sodium laurate and other soaps.
Vulvic acid is used for the preparation of alkyd resins, as well as wetting agents, detergents and pesticides
Vulvic acid is used for peeling vegetables and fruits with a maximum amount of 3.0g/kg.


Vulvic acid is used as defoamer; GB 2760-86 provides for the spices allowed to use; used for the preparation of other food grade additives.
Vulvic acid is widely used in the surfactant industry and can be, according to the classification of surfactants, divided into cationic, anionic, non-ionic and amphoteric type.


The surfactants types of Vulvic acid are listed in the attached table of this item.
Some surfactants of the derivatives of Vulvic acid and dodecanol are also antiseptics, such as dodecyl dimethyl benzyl ammonium chloride (geramine), dodecyl dimethyl benzyl ammonium bromide (bromo-geramine) and dodecyl dimethyl (2-phenoxyethyl) ammonium bromide (domiphen bromide).


The dodecyldimethyllammonium-2,4,5-trichlorophenolate in these derivatives can be used as citrus preservative.
Vulvic acid also has many applications in plastic additives, food additives, spices and pharmaceutical industries.
Given its foaming properties, the derivatives of lauric acid (h-Vulvic acid) are widely used as a base in the manufacture of soaps, detergents, and lauryl alcohol.


Vulvic acid is a common constituent of vegetable fats, especially coconut oil and laurel oil.
Vulvic acid may have a synergistic effect in a formula to help fight against mircoorganisms.
Vulvic acid is a mild irritant but not a sensitizer, and some sources cite it as comedogenic.


Vulvic acid is a fatty acid obtained from coconut oil and other veg- etable fats.
Vulvic acid is practically insoluble in water but is soluble in alcohol, chloroform, and ether.


Vulvic acid functions as a lubricant, binder, and defoaming agent.
Vulvic acid is used intermediates of Liquid Crystals
Vulvic acid is also used as a food additive and an active component in a treatment for acne.


-Uses of Vulvic acid in Perfume:
Vulvic acid is used in Butter flavors and in certain Citrus flavor types, mainly in Lemon.
The concentration of Vulvic acid used may vasy from 2 to 40 ppm, calculated upon the finished consumer product.


-Pharmaceutical Applications of Vulvic acid:
pharmaceutical applications it has also been examined for use as an enhancer for topical penetration and transdermal absorption, rectal absorption, buccal delivery,(14) and intestinal absorption.
Vulvic acid is also useful for stabilizing oil-in-water emulsions.
Vulvic acid has also been evaluated for use in aerosol formulations.



SOLUBILITY OF VULVIC ACID:
Vulvic acid is soluble in water, benzene, acetone, alcohol, petroleum ether, dimethyl sulfoxide and dimethyl formamide.
Vulvic acid is slightly soluble in chloroform.



NOTES OF VULVIC ACID:
Vulvic acid is incompatible with bases, oxidizing agents and reducing agents.



WHERE TO FIND VULVIC ACID:
Vulvic acid is a powerful substance that’s sometimes extracted from the coconut for use in developing monolaurin.
Monolaurin is an antimicrobial agent that’s able to fight pathogens such as bacteria, viruses, and yeasts.



OCCURRENCE OF VULVIC ACID:
Vulvic acid, as a component of triglycerides, comprises about half of the fatty-acid content in coconut milk, coconut oil, laurel oil, and palm kernel oil (not to be confused with palm oil).

Otherwise, Vulvic acid is relatively uncommon.
Vulvic acid is also found in human breast milk (6.2% of total fat), cow's milk (2.9%), and goat's milk (3.1%).

In various plants:
*The palm tree Attalea speciosa, a species popularly known in Brazil as babassu – 50% in babassu oil
*Attalea cohune, the cohune palm (also rain tree, American oil palm, corozo palm or manaca palm) – 46.5% in cohune oil
*Astrocaryum murumuru (Arecaceae) a palm native to the Amazon – 47.5% in "murumuru butter"
*Coconut oil 49%
*Pycnanthus kombo (African nutmeg)
*Virola surinamensis (wild nutmeg) 7.8–11.5%
*Peach palm seed 10.4%
*Betel nut 9%
*Date palm seed 0.56–5.4%
*Macadamia nut 0.072–1.1%
*Plum 0.35–0.38%
*Watermelon seed 0.33%
*Viburnum opulus 0.24-0.33%
*Citrullus lanatus (egusi melon)
*Pumpkin flower 205 ppm, pumpkin seed 472 ppm
*Insect
*Black soldier fly Hermetia illucens 30–50 mg/100 mg fat.



ALTERNATIVE PARENTS OF VULVIC ACID:
*Dicarboxylic acids and derivatives
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF VULVIC ACID:
*Medium-chain fatty acid
*Dicarboxylic acid or derivatives
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Aliphatic acyclic compound



COMPOUND TYPE OF VULVIC ACID:
*Animal Toxin
*Cosmetic Toxin
*Food Toxin
*Industrial/Workplace Toxin
*Metabolite
*Natural Compound
*Organic Compound
*Plasticizer



CHEMICAL PROPERTIES OF VULVIC ACID:
Vulvic acid is a colorless needle-like crystals.
Vulvic acid is soluble in methanol, slightly soluble in acetone and petroleum ether.



STABILITY AND STORAGE CONDITIONS OF VULVIC ACID:
Vulvic acid is stable at normal temperatures and should be stored in a cool, dry place.



SOURCE AND PREPARATION OF VULVIC ACID:
Vulvic acid is a fatty carboxylic acid isolated from vegetable and animal fats or oils.
For example, coconut oil and palm kernel oil both contain high proportions of Vulvic acid.
Isolation from natural fats and oils involves hydrolysis, separation of the fatty acids, hydrogenation to convert unsaturated fatty acids to saturated acids, and finally distillation of the specific fatty acid of interest.



OCCURRENCE OF VULVIC ACID:
Vulvic acid, as a component of triglycerides, comprises about half of the fatty acid content in coconut oil, laurel oil, and in palm kernel oil (not to be confused with palm oil).
Otherwise Vulvic acid is relatively uncommon.
Vulvic acid is also found in human breast milk ( 6.2 % of total fat), cow's milk (2.9%), and goat's milk (3.1 %).



SAFETY OF VULVIC ACID:
Vulvic acid is widely used in cosmetic preparations, in the manufacture of food-grade additives, and in pharmaceutical formulations.
General exposure to Vulvic acid occurs through the consumption of food and through dermal contact with cosmetics, soaps, and detergent products.

Occupational exposure may cause local irritation of eyes, nose, throat, and respiratory tract, although Vulvic acid is considered safe and nonirritating for use in cosmetics.
No toxicological effects were observed when Vulvic acid was administered to rats at 35% of the diet for 2 years.



MEDIUM-CHAIN TRIGLYCERIDES OF VULVIC ACID:
Medium-chain triglycerides, or fatty acids, such as Vulvic acid, are characterized by a specific chemical structure that allows your body to absorb them whole.

This makes them more easily digestible--your body processes them as it would carbohydrates, and they are used as a source of direct energy.
Compared to long-chain triglycerides, the type in other saturated fats, MCTs have fewer calories per serving, roughly 8.3 calories per gram rather than the standard 9 calories per gram, according to an article in "Nutrition Review."



NUTRITIONAL AND MEDICAL ASPECTS OF VULVIC ACID:
Although 95% of medium-chain triglycerides are absorbed through the portal vein, only 25–30% of Vulvic acid is absorbed through it.
Vulvic acid induces apoptosis in cancer and promotes the proliferation of normal cells by maintaining cellular redox homeostasis.
Vulvic acid increases total serum lipoproteins more than many other fatty acids, but mostly high-density lipoprotein (HDL).

As a result, Vulvic acid has been characterized as having "a more favorable effect on total HDL than any other fatty acid [examined], either saturated or unsaturated".
In general, a lower total/HDL serum lipoprotein ratio correlates with a decrease in atherosclerotic incidence.

Nonetheless, an extensive meta-analysis on foods affecting the total LDL/serum lipoprotein ratio found in 2003 that the net effects of Vulvic acid on coronary artery disease outcomes remained uncertain.
A 2016 review of coconut oil (which is nearly half Vulvic acid) was similarly inconclusive about the effects on cardiovascular disease incidence.



INCLUDING VULVIC ACID IN YOUR DIET:
Vulvic acid can be taken as a supplement, but it is most commonly consumed as part of coconut oil or palm kernel oil.
Vulvic acid is considered to be safe based on the amounts generally found in food.

According to NYU Langone Medical Center, coconut and palm kernel oil contain up to 15 percent MCTs, along with a number of other fats.
However, because they are still pure oil, limit your intake of MCTs to stay within the recommended 5 to 7 teaspoons of oil per day as set out by the U.S. Department of Agriculture.

You can use coconut and palm kernel oil for stir-fries because both oils withstand high heat.
They can also be used in baking, adding a natural richness to your food.



PHYSICAL PROPERTIES OF VULVIC ACID:
Vulvic acid occurs as a white crystalline powder with a slight odor of bay oil or a fatty odor.
Vulvic acid is a common constituent of most diets; large doses may produce gastrointestinal upset.



CHEMICAL PROPERTIES OF VULVIC ACID:
Like many other fatty acids, Vulvic acid is inexpensive, has a long shelf-life, and is non-toxic and safe to handle.
Vulvic acid is mainly used for the production of soaps and cosmetics.

For these purposes, Vulvic acid is neutralized with sodium hydroxide to give sodium laurate, which is a soap.
Most commonly, sodium laurate is obtained by saponification of various oils, such as coconut oil.
These precursors give mixtures of sodium laurate and other soaps.



PRODUCTION METHODS OF VULVIC ACID:
1. Industrial production methods can be grouped into two categories:
* derived from the saponification or high temperature and pressure decomposition of natural vegetable oils and fats;
* separated from the synthetic fatty acid.

Japan mainly uses coconut oil and palm kernel oil as the raw materials for the preparation of Vulvic acid.
The natural vegetable oils used to produce Vulvic acid include coconut oil, litsea cubeba kernel oil, palm kernel oil and mountain pepper seed oil.

Other plants oil, such as palm kernel oil, tea tree seed oil and camphor tree seed oil, can also service industry to produce Vulvic acid.
The residual C12 distillate from the extraction of Vulvic acid, containing a large number of dodecenoic acid, can be hydrogenated at atmospheric pressure, without catalyst, to convert into Vulvic acid with a yield of more than 86%.

2. Derived from the separation and purification of coconut oil and other vegetable oil.

3. Vulvic acid naturally exists in coconut oil, litsea cubeba kernel oil, palm kernel oil and pepper kernel oil in the form of glyceride.
Vulvic acid can be derived from the hydrolysis of natural oils and fats in industry.
The coconut oil, water and catalyst are added into the autoclave and hydrolyzed to glycerol and fatty acid at 250 ℃ under the pressure of 5MPa.
The content of Vulvic acid is 45%~80%, and can be further distilled to obtain Vulvic acid.



AIR AND WATER REACTIONS OF VULVIC ACID:
Vulvic acid is insoluble in water.



AROMA THRESHOLD VALUES OF VULVIC ACID:
Aroma threshold values
Aroma characteristics at 1.0%: fatty, creamy, cheeselike, candle waxy with egglike richness



TASTE THRESHOLD VALUES OF VULVIC ACID:
Taste characteristics at 5 ppm: waxy,fatty and oily, tallowlike, creamy and dairylike with a coating mouthfeel



REACTIVITY PROFILE OF VULVIC ACID:
Vulvic acid is a carboxylic acid.
Carboxylic acids donate hydrogen ions if a base is present to accept them.
They react in this way with all bases, both organic (for example, the amines) and inorganic.

Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat.
Neutralization between an acid and a base produces water plus a salt.
Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt.

Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Vulvic acid to corrode or dissolve iron, steel, and aluminum parts and containers.

Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide.
The reaction is slower for dry, solid carboxylic acids.
Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide.



PRODUCTION METHODS OF VULVIC ACID:
Vulvic acid is a fatty carboxylic acid isolated from vegetable and animal fats or oils.
For example, coconut oil and palm kernel oil both contain high proportions of Vulvic acid.
Isolation from natural fats and oils involves hydrolysis, separation of the fatty acids, hydrogenation to convert unsaturated fatty acids to saturated acids, and finally distillation of the specific fatty acid of interest.



PHYSICAL and CHEMICAL PROPERTIES of VULVIC ACID:
Chemical formula: C10H18O4
Molar mass: 202.250 g•mol−1
Density: 1.209 g/cm3
Melting point: 131 to 134.5 °C (267.8 to 274.1 °F; 404.1 to 407.6 K)
Boiling point: 294.4 °C (561.9 °F; 567.5 K) at 100 mmHg
Solubility in water: 0.25 g/L
Acidity (pKa): 4.720, 5.450
Molecular Weight: 202.25
XLogP3: 2.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 4

Rotatable Bond Count: 9
Exact Mass: 202.12050905
Monoisotopic Mass: 202.12050905
Topological Polar Surface Area: 74.6 Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 157
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical state: powder
Color: white
Odor: No data available
Melting point/freezing point:
Melting point/range: 133 - 137 °C - lit.
Initial boiling point and boiling range: 294,5 °C at 133 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,224 g/l at 20 °C - OECD Test Guideline 105
Partition coefficient:
n-octanol/water: log Pow: 1,5 at 23 °C
Vapor pressure: 1 hPa at 183 °C
Density: 1,210 g/cm3 at 20 °C

Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Water Solubility: 0.91 g/L
logP: 1.93
logP: 2.27
logS: -2.4
pKa (Strongest Acidic): 4.72

Physiological Charge: -2
Hydrogen Acceptor Count: 4
Hydrogen Donor Count: 2
Polar Surface Area: 74.6 Ų
Rotatable Bond Count: 9
Refractivity: 51.14 m³•mol⁻¹
Polarizability: 22.61 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: No
MDDR-like Rule: No

Melting point: 133-137 °C (lit.)
Boiling point: 294.5 °C/100 mmHg (lit.)
Density: 1.21
vapor pressure: 1 mm Hg ( 183 °C)
refractive index: 1.422
Flash point: 220 °C
storage temp.: Store below +30°C.
solubility: ethanol: 100 mg/mL
form: Powder or Granules
pka: 4.59, 5.59(at 25℃)
color: White to off-white
Water Solubility: 1 g/L (20 ºC)
Merck: 14,8415

BRN: 1210591
Stability: Stable.
LogP: 1.5 at 23℃
Appearance: white granular powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 130.80 °C. @ 760.00 mm Hg
Boiling Point: 364.00 to 365.00 °C. @ 760.00 mm Hg
Boiling Point: 235.00 to 234.00 °C. @ 10.00 mm Hg
Flash Point: 389.00 °F. TCC ( 198.30 °C. ) (est)
logP (o/w): 1.706 (est)
Soluble in: water, 1000 mg/L @ 20 °C (exp)
water, 1420 mg/L @ 25 °C (est)

Chemical formula: C12H24O2
Molar mass: 200.322 g•mol−1
Appearance: White powder
Odor: Slight odor of bay oil
Density: 1.007 g/cm³ (24 °C),
0.8744 g/cm³ (41.5 °C),
0.8679 g/cm³ (50 °C)
Melting point: 43.8 °C (110.8 °F; 316.9 K)
Boiling point: 297.9 °C (568.2 °F; 571.0 K),
282.5 °C (540.5 °F; 555.6 K) at 512 mmHg,
225.1 °C (437.2 °F; 498.2 K) at 100 mmHg
Solubility in water: 37 mg/L (0 °C), 55 mg/L (20 °C),
63 mg/L (30 °C), 72 mg/L (45 °C), 83 mg/L (100 °C)

Solubility: Soluble in alcohols, diethyl ether,
phenyls, haloalkanes, acetates
Solubility in methanol: 12.7 g/100 g (0 °C),
120 g/100 g (20 °C), 2250 g/100 g (40 °C)
Solubility in acetone: 8.95 g/100 g (0 °C),
60.5 g/100 g (20 °C), 1590 g/100 g (40 °C)
Solubility in ethyl acetate: 9.4 g/100 g (0 °C),
52 g/100 g (20°C), 1250 g/100 g (40°C)
Solubility in toluene: 15.3 g/100 g (0 °C),
97 g/100 g (20°C), 1410 g/100 g (40°C)
log P: 4.6

Vapor pressure: 2.13•10−6 kPa (25 °C),
0.42 kPa (150 °C),
6.67 kPa (210 °C)
Acidity (pKa): 5.3 (20 °C)
Thermal conductivity: 0.442 W/m•K (solid),
0.1921 W/m•K (72.5 °C),
0.1748 W/m•K (106 °C)
Refractive index (nD): 1.423 (70 °C),
1.4183 (82 °C)
Viscosity: 6.88 cP (50 °C), 5.37 cP (60 °C)
Structure:
Crystal structure: Monoclinic (α-form),
Triclinic, aP228 (γ-form)

Space group: P21/a, No. 14 (α-form), P1, No. 2 (γ-form)
Point group: 2/m (α-form)[8], 1 (γ-form)[9]
Lattice constant: a = 9.524 Å, b = 4.965 Å,
c = 35.39 Å (α-form),
α = 90°, β = 129.22°, γ = 90°
Thermochemistry:
Heat capacity (C): 404.28 J/mol•K
Std enthalpy of formation (ΔfH⦵298): −775.6 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): 7377 kJ/mol,
7425.8 kJ/mol (292 K)
Molecular Weight: 200.32 g/mol
XLogP3: 4.2
Hydrogen Bond Donor Count: 1

Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 10
Exact Mass: 200.177630004 g/mol
Monoisotopic Mass: 200.177630004 g/mol
Topological Polar Surface Area: 37.3Ų
Heavy Atom Count: 14
Formal Charge: 0
Complexity: 132
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
IUPAC Name: dodecanoic acid
Traditional IUPAC Name: lauric acid
Formula: C12H24O2
InChI: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChI Key: POULHZVOKOAJMA-UHFFFAOYSA-N
Molecular weight: 200.3178
Exact mass: 200.177630012
SMILES: CCCCCCCCCCCC(O)=O

Chemical Formula: C12H24O2
Average Molecular Weight: 200.3178
Monoisotopic Molecular Weight: 200.177630012
IUPAC Name: dodecanoic acid
Traditional Name: lauric acid
CAS Registry Number: 143-07-7
SMILES: CCCCCCCCCCCC(O)=O
InChI Identifier: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChI Key: POULHZVOKOAJMA-UHFFFAOYSA-N
Synonyms: n-Dodecanoic acid
IUPAC Name: Dodecanoic acid
Canonical SMILES: CCCCCCCCCCCC(=O)O
InChI: POULHZVOKOAJMA-UHFFFAOYSA-N

InChI Key: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
Boiling Point: 225 °C 100mmHg(lit.)
Melting Point: 44-46 °C(lit.)
Flash Point: 156ºC
Density: 0.883g/ml
Appearance: Clear liquid
Storage: Room temperature
CNo.Chain: C12:0
Compound Derivative: Acid
EC Number: 205-582-1
Fatty Acid: Dodecanoic (Lauric)
Hazard Codes: Xi

Hazard Statements: Xi
HS Code: 2916399090
LogP: 3.99190
MDL Number: MFCD00002736
Physical State: Solid
PSA: 37.3
Refractive Index: 1.4304
Safety Description: 37/39-26-39-36
Stability: Stable.
Incompatible with bases, oxidizing agents, reducing agents.
Storage Conditions: Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.

Supplemental Hazard Statements: H401-H318-H319
Symbol: GHS05, GHS07
Vapor Pressure: 1 mm Hg ( 121 °C)
Formula: C12H24O2
InChI: InChI=1S/C12H24O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h2-11H2,1H3,(H,13,14)
InChIKey: POULHZVOKOAJMA-UHFFFAOYSA-N
Molecular Weight: 200.322 g/mol
SMILES: OC(CCCCCCCCCCC)=O
SPLASH: splash10-0706-9000000000-b974e08e305014657f85
Source of Spectrum: HE-1982-0-0
CB Number: CB0357278
Molecular Formula: C12H24O2
Lewis structure
Molecular Weight: 200.32

MDL Number: MFCD00002736
MOL File: 143-07-7.mol
Melting point: 44-46 °C (lit.)
Boiling point: 225 °C/100 mmHg (lit.)
Density: 0.883 g/mL at 25 °C (lit.)
Vapor pressure: 1 mm Hg (121 °C)
Refractive index: 1.4304
FEMA: 2614 | LAURIC ACID
Flash point: >230 °F
Storage temp.: 2-8°C
Solubility: 4.81 mg/L
Form: Crystalline Powder of Flakes
pKa: 4.92 (H2O, t =25.0) (Uncertain)
Specific Gravity: 0.883
Color: White

Odor: at 100.00 % mild fatty coconut bay oil
Odor Type: fatty
Explosive limit: 0.6% (V)
Water Solubility: insoluble
λmax: 207 nm (MeOH) (lit.)
JECFA Number: 111
Merck: 14,5384
BRN: 1099477
Stability: Stable.
Incompatible with bases, oxidizing agents, reducing agents.
InChIKey: POULHZVOKOAJMA-UHFFFAOYSA-N
LogP: 5

Dissociation constant: 5.3 at 20°C
Substances Added to Food (formerly EAFUS): LAURIC ACID
CAS DataBase Reference: 143-07-7 (CAS DataBase Reference)
EWG's Food Scores: 1
FDA UNII: 1160N9NU9U
NIST Chemistry Reference: Dodecanoic acid (143-07-7)
EPA Substance Registry System: Lauric acid (143-07-7)
Molecular Weight: 200.32
Exact Mass: 200.32
BRN: 1099477
EC Number: 205-582-1
HS Code: 29159010

Characteristics
PSA: 37.3
XLogP3: 4.2
Appearance: White Crystalline Powder of Flakes
Density: 0.883 g/cm³ @ Temp: 20 °C
Melting Point: 44.2 °C
Boiling Point: 298.9 °C
Flash Point: >230 °F
Refractive Index: 1.4304
Water Solubility: H2O: insoluble
Storage Conditions: Store below +30°C
Vapor Pressure: 1 mm Hg (121 °C)
Toxicity: LD50 i.v. in mice: 131 ±5.7 mg/kg (Or, Wretlind)
Explosive limit: 0.6% (V)
Odor: Characteristic, like oil of bay
pKa: 5.3 (at 20 °C)



FIRST AID MEASURES of VULVIC ACID:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of VULVIC ACID:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of VULVIC ACID:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of VULVIC ACID:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of VULVIC ACID:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry



STABILITY and REACTIVITY of VULVIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Conditions to avoid:
no information available
WALOCEL CRT 10000 G

Walocel CRT 10000 g is a cellulose ether renowned for its superior thickening capabilities in high-quality silicate emulsion paints.
Walocel CRT 10000 g contributes to the optimal viscosity of paint formulations, ensuring smooth and consistent application.
Characterized by its low surface activity, Walocel CRT 10000 g effectively enhances the stability of silicate emulsion paints.
Walocel CRT 10000 g's no-foaming attribute makes it particularly advantageous, preserving the integrity of paint formulations during application.

CAS Number: 9004-32-4
EC Number: 618-378-6

Carboxy-Methyl Cellulose, E466 (when used as a food additive),9004-32-4, SODIUM CARBOXYMETHYL CELLULOSE, sodium;2,3,4,5,6-pentahydroxyhexanal;acetate, Carboxymethylcellulose sodium (USP), Carboxymethylcellulose cellulose carboxymethyl ether, Celluvisc (TN)



APPLICATIONS


Walocel CRT 10000 g finds widespread application as a premium thickener in the formulation of high-quality silicate emulsion paints.
Its primary role lies in enhancing the viscosity of paint formulations, ensuring optimal consistency for smooth application.

Walocel CRT 10000 g is specifically designed for use in paints that utilize silicate emulsion technology.
Walocel CRT 10000 g's low surface activity makes it particularly suitable for maintaining stability in silicate emulsion paint compositions.

Its no-foaming characteristic is a crucial attribute in paint applications, preserving the integrity of the formulation during mixing and application.
Walocel CRT 10000 g contributes to the stability and longevity of silicate emulsion paints, reducing the risk of settling or separation.
The cellulose ether's high water retention capacity plays a vital role in controlling the rheology of paint formulations.

Lap-free application by brush or roller is achieved, leading to a uniform finish on painted surfaces.
Walocel CRT 10000 g serves as a versatile additive, meeting various performance requirements in the production of high-quality paints.

Walocel CRT 10000 g dissolves readily in water at any temperature, facilitating efficient and convenient paint formulation.
Compatibility with warm water expedites the dissolving process, offering flexibility in manufacturing processes.
Walocel CRT 10000 g's compatibility with granules ensures uniform distribution within the paint, contributing to overall homogeneity.

Its stability under different environmental conditions makes it suitable for a wide range of painting applications.
Walocel CRT 10000 g's efficient thickening properties allow for precise control over the texture and application characteristics of the paint.
With recommended usage levels ranging from 0.2% to 0.6%, it is effective at relatively low concentrations in paint formulations.

During the stirring-in phase, care must be taken to prevent an undesired increase in viscosity and the formation of lumps.
Its incorporation into paint formulations enhances workability, facilitating both professional and DIY applications.

Walocel CRT 10000 g is crucial in preventing lap marks, contributing to the visual appeal of painted surfaces.
Manufacturers prefer this cellulose ether grade for its reliability and consistency in meeting the high standards of paint production.
Its quick dissolving time and effective wetting of granules expedite the paint mixing process, improving manufacturing efficiency.

Walocel CRT 10000 g's no-foaming characteristic simplifies the paint application process, reducing the need for adjustments.
Walocel CRT 10000 g is valued for its contribution to the overall aesthetic quality and durability of painted surfaces.
Walocel CRT 10000 g plays a pivotal role in the production of high-quality paints that meet the demanding standards of the industry.

Walocel CRT 10000 g's versatility extends to both indoor and outdoor paint applications, ensuring a wide range of uses.
Whether used by professionals or homeowners, Walocel CRT 10000 g remains a trusted choice in achieving superior paint performance and application outcomes.

Walocel CRT 10000 g serves as an essential component in the production of architectural paints, contributing to their overall performance and quality.
Its role in silicate emulsion paints extends to exterior coatings, providing durability and weather resistance.
Walocel CRT 10000 g's ability to control viscosity ensures that the paint can be easily applied with a brush, roller, or spray gun.

In industrial settings, Walocel CRT 10000 g is utilized in the formulation of coatings for machinery and equipment, offering protection and a smooth finish.
Walocel CRT 10000 g plays a key role in the manufacturing of high-end decorative paints, contributing to the appeal of interior spaces.

Walocel CRT 10000 g is often employed in the formulation of specialty coatings for surfaces that require specific performance characteristics.
Walocel CRT 10000 g finds application in the creation of textured paints, where its thickening properties contribute to the desired consistency for creating unique patterns.
Walocel CRT 10000 g is a preferred choice in the production of environmentally friendly paints due to its non-toxic nature.
Walocel CRT 10000 g is integral to the formulation of high-performance primers, ensuring proper adhesion and coverage.
Its compatibility with various pigments and additives allows for the creation of a diverse range of paint colors and finishes.

Walocel CRT 10000 g contributes to the prevention of sagging or dripping in vertical applications, ensuring a uniform coating on walls and surfaces.
In the automotive industry, Walocel CRT 10000 g is utilized in the formulation of coatings for vehicles, providing both aesthetic appeal and protective properties.
Walocel CRT 10000 g aids in the production of paints used for artistic purposes, offering artists a reliable medium for their creations.

Walocel CRT 10000 g is a crucial ingredient in the development of fire-retardant paints, enhancing safety in building applications.
Walocel CRT 10000 g's application in the formulation of wood coatings ensures a smooth and protective finish for various wooden surfaces.

Walocel CRT 10000 g's resistance to yellowing makes it suitable for light-colored paints, maintaining the brightness and clarity of the finish.
In the marine industry, the product is used in the formulation of coatings for boats and ships, providing resistance to water and environmental conditions.

Walocel CRT 10000 g contributes to the creation of specialty coatings with antimicrobial properties, suitable for environments requiring hygiene.
Walocel CRT 10000 g is an essential component in the formulation of low-VOC (volatile organic compound) paints, aligning with environmentally conscious practices.
The cellulose ether's ability to prevent settling ensures that pigments and additives remain uniformly distributed throughout the paint.
Walocel CRT 10000 g is employed in the creation of masonry paints, offering protection and enhancing the appearance of brick and concrete surfaces.

Walocel CRT 10000 g is utilized in the production of high-gloss paints, contributing to the reflective and aesthetically pleasing quality of the finish.
Walocel CRT 10000 g is integral to the development of specialty coatings for metal surfaces, providing corrosion resistance and durability.

Walocel CRT 10000 g is used in the formulation of coatings for ceilings, contributing to the overall visual appeal of interior spaces.
Its versatility extends to the production of floor coatings, ensuring a durable and wear-resistant finish in both residential and commercial settings.



DESCRIPTION


Walocel CRT 10000 g is a cellulose ether renowned for its superior thickening capabilities in high-quality silicate emulsion paints.
Walocel CRT 10000 g contributes to the optimal viscosity of paint formulations, ensuring smooth and consistent application.

Characterized by its low surface activity, Walocel CRT 10000 g effectively enhances the stability of silicate emulsion paints.
Walocel CRT 10000 g's no-foaming attribute makes it particularly advantageous, preserving the integrity of paint formulations during application.

Possessing high water retention capacity, it aids in maintaining the desired consistency of the paint over time.
Its versatility is highlighted by a broad property profile, catering to various performance requirements in paint applications.

Walocel CRT 10000 g dissolves readily in water at any temperature, offering convenience in the preparation of paint mixtures.
Walocel CRT 10000 g's compatibility with warm water expedites the dissolving process, facilitating efficient paint formulation.

Lap-free application by brush or roller is a distinctive feature, ensuring a seamless and even finish on painted surfaces.
Walocel CRT 10000 g demonstrates excellent wetting of granules, promoting uniform distribution within paint compositions.

Designed for high-quality silicate emulsion paints, it aligns with the stringent requirements of such paint formulations.
Walocel CRT 10000 g grade is free from undesirable surface effects, contributing to the overall aesthetic appeal of painted surfaces.
Its stability under varying temperatures makes it a reliable choice for paint formulations exposed to different environmental conditions.

Walocel CRT 10000 g's efficient thickening capabilities allow for precise control over the paint's texture and application characteristics.
With no compromise on water retention, Walocel CRT 10000 g ensures the longevity and durability of painted surfaces.

The quick dissolving time, especially with warm water, adds an element of efficiency to the paint mixing process.
During the stirring-in phase, care must be taken to prevent an undesired increase in viscosity and the formation of lumps.

Walocel CRT 10000 g's recommended usage level, ranging from 0.2% to 0.6%, attests to its effectiveness at relatively low concentrations.
Its incorporation into paint formulations requires vigorous stirring to achieve the desired homogeneity.
The cellulose ether grade plays a crucial role in preventing lap marks, enhancing the overall appearance of painted surfaces.

A preferred choice for manufacturers, Walocel CRT 10000 g meets the demanding standards of high-quality paint production.
Walocel CRT 10000 g contributes to the overall workability of silicate emulsion paints, facilitating both professional and DIY applications.

During storage, Walocel CRT 10000 g maintains its properties, ensuring consistency and reliability in subsequent paint batches.
Walocel CRT 10000 g's no-foaming characteristic simplifies the application process, reducing the need for additional adjustments.
Walocel CRT 10000 g stands as a testament to innovation in cellulose ether technology, delivering enhanced performance in silicate emulsion paints.



PROPERTIES


Appearance: White to slightly yellowish powder
Solubility: Water soluble; delayed solubility in pH-neutral cold water
Viscosity, mPa•s: 10,000-15,000
pH (2% solution): Neutral
Volatiles, water, %, max: 10



FIRST AID


Inhalation:

If inhaled, move the affected person to fresh air.
If respiratory irritation or difficulty breathing occurs, seek medical attention.


Skin Contact:

In case of skin contact, wash affected areas with plenty of water.
Remove contaminated clothing.
If irritation persists, seek medical advice.


Eye Contact:

In case of contact with the eyes, rinse immediately with plenty of water for at least 15 minutes.
If irritation persists, seek medical attention, and bring the product's container or label for reference.


Ingestion:

If swallowed, rinse mouth and drink plenty of water.
Do not induce vomiting unless directed by medical personnel.
Seek medical attention.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves and safety glasses, to minimize contact with the product.

Ventilation:
Use the product in a well-ventilated area to prevent the accumulation of vapors or dust.

Avoidance of Contact:
Avoid skin and eye contact; in case of contact, follow recommended first aid measures.

Hygiene Practices:
Wash hands thoroughly after handling the product and before eating, drinking, or using the restroom.

Avoiding Inhalation:
If the product generates dust or vapors, use local exhaust ventilation or respiratory protection to prevent inhalation.


Storage:

Location:
Store Walocel CRT 10000 g in a cool, dry, and well-ventilated area.

Temperature:
Keep the product within the specified temperature range as indicated by the manufacturer.

Containers:
Store in original containers or containers made of compatible materials as recommended by the manufacturer.

Seal Containers:
Keep containers tightly sealed when not in use to prevent contamination or moisture absorption.

Separation:
Store away from incompatible materials, such as strong acids, alkalis, or oxidizing agents.

Handling Precautions:
Follow recommended handling procedures to avoid spills or leaks during storage.

Protection from Physical Damage:
Protect containers from physical damage that could compromise their integrity.
WALOCEL CRT 10000 G CELLULOSE ETHER
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is a thickener based on cellulose ether, particularly suitable for high-quality silicate emulsion paints.
Characterized by WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER 's broad property profile, low surface activity, no foaming, high water retention capacity, allows lap-free application by brush or roller.
Dissolves readily in water at any temperature.

CAS: 9004-32-4
MF: C6H7O2(OH)2CH2COONa
EINECS: 618-378-6

Synonyms
Aquacide I, Calbiochem;Aquacide II, Calbiochem;Carboxyl Methyl Cellulose sodium;Cellex;Cellulose carboxymethyl ether, sodium;cellulose gum;SODIUM CARBOXY METHYL CELLULOSE (CMC);SCMC(SODIUM CARBOXY METHYL CELULLOSE

The dissolving time can be reduced by using warm water.
Should be added to the paint formulation by stirring vigorously.
Must be carried out relatively quickly to prevent an increase in viscosity and the formation of lumps during the stirring-in phase.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER ensure adequate wetting of the granules.
Recommended usage level is 0.2 to 0.6%.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is a water-soluble polymer.
As a solution in water, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER has thixotropic properties.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is useful in helping to hold the components of pyrotechnic compositions in aqucous suspension (e.g., in the making of black match).

WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also an especially effective binder that can be used in small amounts in compositions, where the binder can intcrfere with the intended effect (e.g., in strobe compositions).
However, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER 's sodium content obviously precludes its use in most color compositions.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is manufactured from cellulose by various proccsses that replacc some of the hy drogen atoms in the hydroxyl[OH] groups of the cellulose molecule with acidic carboxymethyl [-CH2CO.OH] groups,which are neutralized to form the corresponding sodium salt.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is white when pure; industrial grade material may be grayish-white or cream granules or powder.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is tackifier, at room temperature, it is non-toxic tasteless white flocculent powder, it is stable and soluble in water, aqueous solution is neutral or alkaline transparent viscous liquid, it is soluble in other water-soluble gums and resins, it is insoluble in organic solvents such as ethanol.

WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is the substituted product of cellulosic carboxymethyl group.
According to their molecular weight or degree of substitution, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER can be completely dissolved or insoluble polymer, the latter can be used as the weak acid cation of exchanger to separate neutral or basic proteins.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER can form highly viscous colloidal solution with adhesive, thickening, flowing, emulsifying, shaping, water, protective colloid, film forming, acid, salt, suspensions and other characteristics, and it is physiologically harmless, so it is widely used in the food, pharmaceutical, cosmetic, oil, paper, textiles, construction and other areas of production.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is incompatible with strongly acidic solutions and with the soluble salts of iron and some other metals, such as aluminum, mercury, and zinc.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also incompatible with xanthan gum.

Precipitation may occur at pH < 2, and also when WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is mixed with ethanol (95%).
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER forms complex coacervates with gelatin and pectin.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER also forms a complex with collagen and is capable of precipitating certain positively charged proteins.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used in food as a viscosity modifier, thickener, to stabilise emulsions and are found in gluten-free and reduced-fat products.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also a constituent of toothpaste, laxatives, diet pills, water-based paints, detergents, textile sizing, and various paper products.
In laundry detergents, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used as a soil suspension polymer.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also used in pharmaceuticals as a thickening agent and in the oil-drilling industry as a viscosity modifier and water-retaining agent.

WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER Chemical Properties
Melting point: 274 °C (dec.)
Density: 1,6 g/cm3
FEMA: 2239 | CARBOXYMETHYLCELLULOSE
Storage temp.: room temp
Solubility H2O: 20 mg/mL, soluble
Form: low viscosity
Pka: 4.30(at 25℃)
Color: White to light yellow
Odor: Odorless
PH Range: 6.5 - 8.5
PH: pH (10g/l, 25℃) 6.0~8.0
Water Solubility: soluble
Merck: 14,1829
Stability: Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System: WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER (9004-32-4)

Uses
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is a thickener, binder, and emulsifier equivalent to cellulose fiber.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is resistant to bacterial decomposition and provides a product with uniform viscosity.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER can prevent skin moisture loss by forming a film on the skin’s surface, and also help mask odor in a cosmetic product.
Constituents are any of several fibrous substances consisting of the chief part of a plant’s cell walls (often extracted from wood pulp or cotton).
In drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes, as protective colloid in general.
As stabilizer in foods.
Pharmaceutic aid (suspending agent; tablet excipient; viscosity-increasing agent).
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used in drilling muds, in detergents as a soil-suspending agent, in resin emulsion paints, adhesives, printing inks, textile sizes and protective colloid.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER acts as a stabilizer in foods.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also employed in pharmaceuticals as a suspending agent and excipients for tablets.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used as viscosity modifiers to stabilize the emulsions.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used as a lubricant in artificial tears and it is used to characterize enzyme activity from endoglucanases.

Pharmaceutical Applications
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is the sodium salt of carboxymethyl cellulose, an anionic derivative.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is widely used in oral and topical pharmaceutical formulations, primarily for its viscosity-increasing properties.
Viscous aqueous solutions are used to suspend powders intended for either topical application or oral and parenteral administration.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER may also be used as a tablet binder and disintegrant, and to stabilize emulsions.
Higher concentrations, usually 3–6%, of the medium-viscosity grade are used to produce gels that can be used as the base for applications and pastes; glycols are often included in such gels to prevent them drying out.

WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also used in self-adhesive ostomy, wound care, and dermatological patches as a muco-adhesive and to absorb wound exudate or transepidermal water and sweat.
This muco-adhesive property is used in products designed to prevent post-surgical tissue adhesions; and to localize and modify the release kinetics of active ingredients applied to mucous membranes; and for bone repair.
Encapsulation with WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER can affect drug protection and delivery.
There have also been reports of its use as a cyto-protective agent.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also used in cosmetics, toiletries, surgical prosthetics, and incontinence, personal hygiene, and food products.

Specific culinary uses
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER powder is widely used in the ice cream industry, to make ice creams without churning or extremely low temperatures, thereby eliminating the need for conventional churners or salt ice mixes.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used in baking breads and cakes.
The use of CMC gives the loaf an improved quality at a reduced cost, by reducing the need of fat.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also used as an emulsifier in biscuits.
By dispersing fat uniformly in the dough, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER improves the release of the dough from the moulds and cutters, achieving well-shaped biscuits without any distorted edges.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER can also help to reduce the amount of egg yolk or fat used in making the biscuits.
Use of WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER in candy preparation ensures smooth dispersion in flavor oils, and improves texture and quality.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used in chewing gums, margarines and peanut butter as an emulsifier.

Other uses
In laundry detergents, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used as a soil suspension polymer designed to deposit onto cotton and other cellulosic fabrics, creating a negatively charged barrier to soils in the wash solution.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also used as a thickening agent, for example, in the oil-drilling industry as an ingredient of drilling mud, where it acts as a viscosity modifier and water retention agent.

WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is sometimes used as an electrode binder in advanced battery applications (i.e. lithium ion batteries), especially with graphite anodes.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER 's water solubility allows for less toxic and costly processing than with non-water-soluble binders, like the traditional polyvinylidene fluoride (PVDF), which requires toxic n-methylpyrrolidone (NMP) for processing.
WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is often used in conjunction with styrene-butadiene rubber (SBR) for electrodes requiring extra flexibility, e.g. for use with silicon-containing anodes.

WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is also used in ice packs to form a eutectic mixture resulting in a lower freezing point, and therefore more cooling capacity than ice.
Aqueous solutions of WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER have also been used to disperse carbon nanotubes, where the long CMC molecules are thought to wrap around the nanotubes, allowing them to be dispersed in water.
In conservation-restoration, WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER is used as an adhesive or fixative.

Production Methods
Alkali cellulose is prepared by steeping cellulose obtained from wood pulp or cotton fibers in sodium hydroxide solution.
The alkaline cellulose is then reacted with sodium monochloroacetate to produce WALOCEL CRT 10000 G CELLULOSE ETHER CELLULOSE ETHER CELLULOSE ETHER .
Sodium chloride and sodium glycolate are obtained as by-products of this etherification.
WALOCEL CRT 20000 PV


Walocel CRT 20000 PV is a type of cellulose ether, specifically a hydroxyethyl cellulose (HEC) derivative.
Cellulose ethers are a group of water-soluble polymers derived from cellulose, a natural polymer found in plants.

CAS Number: 9004-32-4
EC Number: 618-378-6

Synonyms: Hydroxyethyl cellulose, HEC, Natrosol, Natrosol HEC, Natrosol Plus, Cellosize, Tylose, Bermocoll, Methocel, Culminal, ShinEtsu HEC, Dow HEC, Hercules HEC, Walocel, Aquacoat, Culminal, Nisso HEC, Methocel, Tylopur, and Cellulosic Hydroxyethyl Ether, Polyvinyl alcohol, PVA, PVOH, Vinol, Elvanol, Mowiol, Gelvatol, Airvol, Kuraray Poval, Vinylon, Celvol, Gohsenol, and Polyviol



APPLICATIONS


Walocel CRT 20000 PV may be used as a thickener and stabilizer in water-based paints and coatings, improving viscosity control and brushability.
Walocel CRT 20000 PV could serve as a binder in ceramic tile adhesives, enhancing adhesion to substrates and reducing sagging during application.

Walocel CRT 20000 PV might be incorporated into cementitious tile grouts to improve workability and water retention, ensuring proper curing and adhesion.
Walocel CRT 20000 PV could be utilized as a rheology modifier in wallpaper pastes, providing good adhesion and spreadability.
Walocel CRT 20000 PV may find application in the formulation of construction chemical additives such as waterproofing compounds and self-leveling compounds, improving flow and workability.

Walocel CRT 20000 PV could serve as a thickening agent in joint compounds and textured coatings, imparting smooth application and uniform texture.
Walocel CRT 20000 PV might be used in the production of water-based adhesives for paperboard lamination and packaging applications, providing good tack and bond strength.

Walocel CRT 20000 PV could be incorporated into personal care products such as shampoo and shower gels as a thickener and stabilizer, enhancing viscosity and foam stability.
Walocel CRT 20000 PV may find application in toothpaste formulations as a binding and thickening agent, improving texture and mouthfeel.

Walocel CRT 20000 PV could be used in the formulation of topical pharmaceutical gels and creams, providing controlled release of active ingredients and smooth application.
Walocel CRT 20000 PV might find application in the food industry as a thickening agent in sauces, dressings, and desserts, improving texture and mouthfeel.

Walocel CRT 20000 PV could be used in the production of water-based ink formulations for printing applications, providing good flow and printability.
Walocel CRT 20000 PV may find application in the formulation of textile printing pastes as a thickener and binder, improving color yield and washfastness.

Walocel CRT 20000 PV could be incorporated into drilling mud formulations in the oil and gas industry to improve viscosity and suspension properties.
Walocel CRT 20000 PV might be used in the production of latex-based architectural coatings, providing good brushability and leveling properties.

Walocel CRT 20000 PV could serve as a binder and thickener in detergent formulations, improving stability and dispersion of active ingredients.
Walocel CRT 20000 PV may find application in the formulation of polymer dispersions and emulsions for adhesives and coatings, providing good film-forming properties.

Walocel CRT 20000 PV could be used as a binder in ceramic body formulations for tile and pottery production, improving green strength and extrudability.
Walocel CRT 20000 PV might find application in the formulation of fire-retardant coatings for building materials, providing good adhesion and flame resistance.

Walocel CRT 20000 PV could be incorporated into seed coatings to improve adhesion and protectants, enhancing germination and crop yield.
Walocel CRT 20000 PV may find application in the formulation of battery electrolytes as a thickening agent, providing good conductivity and stability.

Walocel CRT 20000 PV could be used as a film-forming agent in the production of water-soluble packaging materials and biodegradable films.
Walocel CRT 20000 PV might find application in the formulation of heat-sealable coatings for flexible packaging materials, providing good adhesion and seal strength.

Walocel CRT 20000 PV could be incorporated into hair care products such as styling gels and mousses as a thickener and film-former, enhancing hold and shine.
Walocel CRT 20000 PV may find application in the formulation of agricultural formulations such as seed coatings and foliar sprays, providing good adhesion and spreadability.

Walocel CRT 20000 PV may find application in the formulation of adhesives for paper and packaging, providing good tack and adhesion to various substrates.
Walocel CRT 20000 PV could be used as a thickening agent in latex-based caulks and sealants, improving viscosity and extrudability.
Walocel CRT 20000 PV might be incorporated into textile printing pastes as a thickener and binder, enhancing color yield and print definition.

Walocel CRT 20000 PV could serve as a suspending agent in suspension fertilizers, preventing settling and ensuring uniform distribution of nutrients.
Walocel CRT 20000 PV may find application in the formulation of antifoaming agents for industrial processes, preventing foam formation and improving efficiency.

Walocel CRT 20000 PV could be used as a binder in ceramic glazes and engobes, improving adhesion and surface finish.
Walocel CRT 20000 PV might find application in the formulation of lubricants and greases as a thickening agent, providing good film-forming properties and lubricity.

Walocel CRT 20000 PV could serve as a stabilizer in emulsion polymerization reactions, improving particle size distribution and stability.
Walocel CRT 20000 PV may find application in the production of water-based drilling fluids for the oil and gas industry, providing good rheological properties and suspension.

Walocel CRT 20000 PV could be used in the formulation of water-based wood stains and finishes, providing good flow and leveling properties.
Walocel CRT 20000 PV might find application in the production of casting slurries for ceramic and metal casting, improving moldability and surface finish.
Walocel CRT 20000 PV could be incorporated into printing inks as a thickener and binder, enhancing print definition and color saturation.

Walocel CRT 20000 PV may find application in the formulation of battery separators for lithium-ion batteries, providing good electrolyte retention and ion conductivity.
Walocel CRT 20000 PV could be used as a binder in the production of fiberglass and composite materials, improving adhesion and mechanical properties.

Walocel CRT 20000 PV might find application in the production of detergents and cleaning products as a thickening and stabilizing agent.
Walocel CRT 20000 PV could serve as a binder in the production of abrasive products such as grinding wheels and sandpaper, improving bond strength and durability.

Walocel CRT 20000 PV may find application in the formulation of inkjet printing fluids as a viscosity modifier and stabilizer, improving print quality and reliability.
Walocel CRT 20000 PV could be used in the production of dietary supplements and pharmaceutical tablets as a binder and disintegrant, ensuring proper dissolution and bioavailability.

Walocel CRT 20000 PV might find application in the formulation of film coatings for oral solid dosage forms, providing moisture protection and taste masking.
Walocel CRT 20000 PV could be incorporated into hydraulic fracturing fluids for oil and gas extraction, providing good suspension and fluid loss control.

Walocel CRT 20000 PV may find application in the production of gel candles and wax melts as a thickening agent, improving fragrance dispersion and burn time.
Walocel CRT 20000 PV could serve as a binder in the production of ceramic membranes for water filtration, improving pore structure and permeability.
Walocel CRT 20000 PV might be used in the formulation of corrosion inhibitors and rust preventatives for metal surfaces, providing good adhesion and barrier protection.

Walocel CRT 20000 PV could be incorporated into personal lubricants and intimate gels as a thickener and moisturizer, enhancing lubricity and comfort.
Walocel CRT 20000 PV may find application in the production of biodegradable packaging materials and disposable products, providing good strength and water resistance.



DESCRIPTION


Walocel CRT 20000 PV is a type of cellulose ether, specifically a hydroxyethyl cellulose (HEC) derivative.
Cellulose ethers are a group of water-soluble polymers derived from cellulose, a natural polymer found in plants.

Walocel CRT 20000 PV is often used as a thickener, stabilizer, and film-forming agent in various industries such as construction, pharmaceuticals, personal care, and food.
Its properties make it suitable for applications such as improving the viscosity and rheology of liquid products, enhancing the texture and stability of emulsions, and controlling the release of active ingredients in pharmaceutical formulations.

Walocel CRT 20000 PV is a water-soluble polymer derived from cellulose, a natural polysaccharide found in plant cell walls.
Walocel CRT 20000 PV is commonly used as a thickener, binder, and film-former in various industrial and consumer products.

Its chemical structure consists of cellulose chains with hydroxyethyl groups attached to the cellulose backbone.
Walocel CRT 20000 PV is typically sold as a white to off-white powder or granules with varying viscosities.

When dispersed in water, HEC forms clear, viscous solutions with excellent stability over a wide pH range.
Walocel CRT 20000 PV is known for its pseudoplastic or shear-thinning behavior, meaning its viscosity decreases under shear stress.

Walocel CRT 20000 PV exhibits high compatibility with other polymers and additives, making it versatile in formulations.
The viscosity of Walocel CRT 20000 PV solutions can be adjusted by varying the polymer concentration and shear rate.
Walocel CRT 20000 PV is used in applications such as paints, adhesives, cosmetics, personal care products, and pharmaceuticals.

In paint formulations, Walocel CRT 20000 PV acts as a rheology modifier, improving sag resistance, spatter resistance, and open time.
In adhesives, HEC provides thickening and binding properties, enhancing adhesive strength and tack.

Walocel CRT 20000 PV is widely used in cosmetics and personal care products as a thickener, stabilizer, and emulsifier.
Walocel CRT 20000 PV imparts smooth texture, uniformity, and enhanced film-forming properties to creams, lotions, and hair care products.



PROPERTIES


Appearance: White to off-white powder or granules.
Odor: Odorless.
Solubility: Soluble in water, forming clear to slightly turbid solutions.
Molecular Weight: Varies depending on the degree of substitution and polymerization.
Density: Typically ranges from 1.3 to 1.5 g/cm³.
Melting Point: Decomposes before melting.
Viscosity: Exhibits pseudoplastic behavior, with viscosity decreasing under shear stress.
pH: Usually neutral in aqueous solution.
Hygroscopicity: Absorbs moisture from the air.



FIRST AID


Inhalation:

If inhaled, immediately move the affected person to fresh air.
Ensure that the individual can breathe comfortably.
If breathing difficulties persist or if the person is not breathing, seek medical attention promptly.
Keep the affected person calm and reassured.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected area thoroughly with soap and water for at least 15 minutes.
If irritation, redness, or discomfort persists, seek medical advice.
If HEC comes into contact with sensitive skin or open wounds, seek medical attention promptly.


Eye Contact:

Flush the eyes with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if irritation is not initially present.
Remove contact lenses if easily removable after flushing.
Protect the unaffected eye during flushing to prevent cross-contamination.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water and spit out.
Do not give anything by mouth to an unconscious person.
Seek medical attention immediately.
Provide medical personnel with information on the amount ingested and the time of ingestion.



HANDLING AND STORAGE

Handling:

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves, safety goggles, and protective clothing, to minimize skin and eye contact.
Use respiratory protection, such as a dust mask or respirator, if handling HEC in powdered form or in dusty environments.
Ensure all PPE is in good condition and properly fitted before handling HEC.

Handling Precautions:
Handle HEC in a well-ventilated area to minimize inhalation exposure.
Avoid generating dust or aerosols when handling the solid compound.
Use tools and equipment designed for handling powders to minimize the risk of spills and dust generation.
Do not eat, drink, or smoke while handling HEC.
Wash hands thoroughly after handling to remove any residual product.


Storage:

Storage Conditions:
Store HEC in a cool, dry, well-ventilated area away from heat, sparks, and open flames.
Keep containers tightly closed when not in use to prevent contamination and evaporation.
Store away from incompatible materials, such as strong oxidizing agents and acids.
Ensure storage area is equipped with appropriate containment measures to contain spills.
Store in containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Check containers regularly for signs of damage or leakage and replace if necessary.

Segregation and Separation:
Segregate HEC from incompatible materials, such as acids, bases, and strong oxidizing agents.
Store HEC away from food, beverages, and feedstuffs to prevent contamination.

Handling and Storage Equipment:
Use equipment and containers specifically designated for handling HEC to prevent cross-contamination.
Ensure equipment used for transferring or dispensing HEC is clean and free from residues of incompatible materials.

Emergency Procedures:
Familiarize personnel with emergency procedures in case of spills, leaks, or exposure incidents.
Maintain spill kits and absorbent materials readily available for immediate response to spills.
Train personnel on proper handling procedures and emergency response protocols.
Waxes
Bees wax; Carnauba wax; Candelilla wax; Paraffin wax; CAS NO: 8012-89-3 CAS NO: 8015-86-9 CAS NO:8006-44-8 CAS NO:8002-74-2
WHEAT GERM OIL
Wheat germ oil is extracted from the germ and is a rich source of polyunsaturated fats.
Wheat germ oil does not have fiber but contains vitamin E and other potential anti-inflammatory compounds.
Wheat germ oil can be taken in capsule form as a supplement, in salad dressings, drizzled on vegetables, or as a topical agent for hair, skin, and nails.



CAS Number: 84012-44-2 ; 68917-73-7
EC Number: 281-689-7
Inci Name: Tritucum Vulgare Oil
Formula: unspecified


Wheat germ oil is obtained from the central whitish seeds of wheat (Triticum vulgare L.) a plant grown in large parts of the world, the largest producers being Russia, Ukraine, China, the USA and Canada.
Wheat germ oil after the first pressing is an intense brown, clear and with a characteristic odour of cereals.


Wheat germ oil is light yellow and with a smooth odour.
Wheat germ oil is high in vitamin E (antioxidant) and sterols.
Due to the high content of vitamin E, Wheat germ oil is an oil with an anti-ageing effect on the skin.


Sterols contribute to skin cell regeneration.
Wheat germ oil is balanced composition between oleic and palmitic (20% and 20%).
The rest are linoleic and linolenic (50% and 8% respectively).


Wheat germ oil revitalizes dry skin.
Due to its high content of essential omega-3 and 6 fatty acids and other nutritionally important substances, wheat germ oil is a real treasure for the whole family.


Wheat germ oil has a pleasant, fine grain taste for which you can add it to salads, RAW desserts and any cold dish.
Wheat germ oil is also suitable for direct consumption, often called „on a spoon“.
Wheat is the primary staple food in India.


Wheat bran and wheat germ are two parts of wheat grain; the outer coat of the grain and the reproductive part of the grain, respectively.
Wheat germ oil gets extracted from the germ part of the wheat grain. Wheat germ is the heart of the wheat kernel.
The germ part of wheat is the nutrient-dense core with the highest protein, vitamins, and minerals content.


Wheat germ oil is derived from wheat germ, which is considered the "heart" of wheat since it's found at the center of the wheat berry.
Wheat germ oil feeds the wheat plant with nutrients to help it germinate and grow.
Wheat germ is the most nutritious component of the wheat kernel and contains 23 different nutrients, including protein, B vitamins, omega-3 fatty acids, iron and calcium.


Wheat germ oil is also nutrient-packed, which makes it particularly well-suited to moisturizing and soothing your skin.
Wheat-germ oil is readily absorbed by your skin, which makes it an effective moisturiser.
When applied to your skin, Wheat germ oil delivers a healthy infusion of vitamin A, vitamin D, B vitamins, antioxidants and fatty acids.


These nutrients therefore, will help moisturise and heal dry or cracked skin.
This why we use Wheat germ oil in our baby care cream and the moisturising baby lotion.
Wheat Germ Food Oil contains wheat germ oil extracted by cold-pressing the small embryo inside the wheat grain (Triticum aestivum).


This extraction method guarantees the optimal condition of all its properties.
Wheat Germ is the embryo of the wheat grain.
Wheat germ oil is separated during the milling of wheat and used for different applications such as in food, pharmaceuticals and for other biological purposes.


Wheat germ oil is golden, slightly brown, and counts on a very pleasant cereal taste and aroma.
Wheat germ oil is a rich, nourishing oil derived from the seed embryos of a wheat plant, often extracted by cold pressing.
It’s often referred to as ‘liquid gold’ because Wheat germ oil is the richest natural source of vitamin E.


Wheat germ oil’s also loaded with essential fatty acids like linoleic, which has been shown to help strengthen hair follicles while softening hair and maintaining moisture.
Wheat germ is the part of the embryo that gives wheat its nutritional value.


Germ is the part of wheat that is a protein store.
While obtaining the wheat flour used in bread making, the part we call the germ is unfortunately decomposed on the grounds that it shortens the shelf life.
Wheat Germ Oil is obtained by the cold press method of the germ.


Wheat Germ Oil is a source of magnesium, zinc, thiamine, folate, potassium and phosphorus.
Wheat Germ Oil is rich in vitamin E, an essential nutrient with antioxidant properties.
Wheat germ oil also contains B vitamins and group A vitamins.


Wheat germ oil can do wonders for your skin.
Its high antioxidant value makes Wheat germ oil a great anti-aging treatment and can help reduce the appearance of wrinkles and fine lines.
Wheat germ oil provides shiny, healthy-looking hair.


Wheat germ oil is extracted from the germ of the wheat kernel, which makes up only 2.5% by weight of the kernel.
Wheat germ oil is particularly high in octacosanol - a 28-carbon long-chain saturated primary alcohol found in a number of different vegetable waxes.
Octacosanol has been studied as an exercise- and physical performance-enhancing agent.


Very long chain fatty alcohols obtained from plant waxes and beeswax have been reported to lower plasma cholesterol in humans.
Wheat germ oil is also very high in vitamin E (255 mg/100g), and has the highest content of vitamin E of any food that has not undergone prior preparation or vitamin fortification.


As a cooking oil, wheat germ oil is strongly flavored, expensive and easily perishable.
Wheat germ oil contains the following fatty acids:
Other uses of wheat germ oil have also been explored, including increasing blood flow and reaction time.


Wheat germ oil is a food supplement that provides vitamin E obtained from wheat germ, and soy oil, extracted from fresh wheat germ and soybeans by the cold pressed method.
The vitamin E provided by this product is a D-alpha-tocopherol, which is the most potent form of vitamin E for humans.


Vitamin E contributes to the protection of cells from oxidative stress.
Wheat is a cereal crop of great importance throughout the world, belonging to the Triticum family.
The charred grains obtained as a result of the excavations show that the wheat plant has an average of 8000 years of history.


The homeland is thought to be Mesopotamia.
It can be divided into different groups according to planting time, color, structural features and purpose of use.
Wheat is the most important grain because it is the main ingredient of flour, semolina, pasta, bread and various bakery products.


Wheat grain consists of bran, germ (embryo) and endosperm.
Only 1 kilogram of wheat germ can be obtained from 1 ton of wheat.
Wheat germ is the embryo found at the bottom of the wheat grain.


Germ is the part of the seed that provides reproduction and germination, so it is the life source of wheat.
Germ, which is a rich mineral and vitamin store, is a source of especially plant-based E and B group vitamins.
The "natural vitamin E" called "alpha-tocopherol" is obtained from wheat germ.


Although wheat germ and wheat bran are the most functional parts of wheat, they have been removed from our lives with industrialization.
Because the production of bread with bran causes it to harden like pasta.
On the other hand, when wheat germ is ground with wheat, when the unsaturated fatty acids in it come into contact with air, it causes darkening in color and bitterness in taste.


Wheat germ is not found in white bread, but is an important nutritional component of whole-grain wheat.
While the shelf life of the flours we used a long time ago was 6 months at the most, Wheat germ oil was extended up to 2 years with the removal of bran and germ.


Wheat germ is a great source of vegetable protein, along with fiber and healthy fats.
Wheat germ oil is also a good source of magnesium, zinc, thiamine, folate, potassium and phosphorus.
Wheat germ oil obtained from wheat germ contains Omega 3, 6, 9 fatty acids that our body cannot produce and we need to get from outside.


The ratio of Omega 3 and Omega 6 Wheat germ oil contains is 1/6 as recommended by the FDA.
Fatty acid deficiencies can be seen in individuals fed with a single type of fat.
In individuals using wheat germ oil, the plant Omega 3 needs are met.


Wheat germ oil is also a good source of other vitamins, minerals and nutrients, including vitamins A, B1, B3, B5, B6 and E, folic acid, riboflavin, thiamine, magnesium, iron, zinc, potassium, fiber, phosphorus and calcium.
Wheat germ oil offers many benefits thanks to the fatty acids it contains.


Wheat germ oil is cold-pressed from wheatgerm and ultrafiltered.
The yellowish-gold oil, Wheat germ oil, contains vitamin E and secondary phytochemicals.
Wheat germ oil goes wonderfully with vegetables, rice, noodles or potatoes.
Wheat germ oil can try a little drizzled-over salad to add additional flavour and nutrients!



USES and APPLICATIONS of WHEAT GERM OIL:
Wheat germ oil has a sweet, slightly nutty, and pleasant grainy flavour and offers vitamins and antioxidants higher than any other natural oil.
Therefore, Wheat germ oil is suitable for culinary, medicinal, and therapeutic purposes.
Wheat Germ Oil is used for systemic support of the body.


Wheat germ oil provides ingredients with antioxidant activity
Wheat germ oil is important for cell-signaling molecules
Wheat germ oil supports the cells of the immune system and the body's natural inflammatory response function as it relates to periodic challenges like consumption of a high-fat meal or strenuous activity


Wheat germ oil supports the body's function during exercise
Wheat germ oil is used for hair care and the face.
When applied to your skin, Wheat germ oil delivers a healthy infusion of vitamin A, vitamin D, B vitamins, antioxidants and fatty acids.


These nutrients therefore, will help moisturise and heal dry or cracked skin.
This why we use Wheat germ oil in our baby care cream and the moisturising baby lotion.
Wheat germ is the most nutritious component of the wheat kernel and contains 23 different nutrients, including protein, B vitamins, omega-3 fatty acids, iron and calcium.


Wheat germ oil is also nutrient-packed, which makes it particularly well-suited to moisturizing and soothing your skin.
Wheat germ oil is not recommended for cooking.
Only for raw consumption, for example Wheat germ oil is added to salads, soups, sauces or dressings (see directions for use).


Wheat Germ Oil is used for systemic support of the body.
Wheat germ oil is used directly on the skin - apply the oil to the face and body.
Wheat germ oil is usually used in relaxation and beauty techniques.


Wheat germ oil is used for the care of nails and dry and brittle hair.
Wheat germ oil is used as an ideal ingredient for home peels due to the high content of natural vitamin E addition to conditioners with hair regenerating properties.


Wheat germ oil is used as an ingredient in the production of lotions, soaps, shampoos.
Wheat germ oil is used downtreatment of sunburns as well.
The demand for vegetable oil has risen rapidly due to the awareness of vegetable oil as food and nutraceuticals (health-enhancing food).


Cereals are an essential mode of a balanced nutrition.
Some cereals like wheat (Triticum aestivum), commonly known as ghehu, have gained much popularity due to their ability to be grounded into flour.
Wheat germ is a by-product derived from wheat milling process.


Wheat germ is used in the cosmetic, food and medical industry.
Egypt is one of the largest producers of wheat germ.
Wheat germ oil has a slightly nutty, pleasantly grainy, sweet flavour with several potential uses.


Wheat germ oil can also be used in cosmetics or as a massage oil.
Wheat germ oil is very popular as a massage oil for pregnant women.
Wheat germ oil is used for Vegetable Dishes, For Potatoes, For Noodles and Pasta, For Rice Dishes.


Wheat germ oil is ideal for mature skin, has beneficial effects, helps fight wrinkles and generally brightens the skin and gives it a healthy look.
Wheat germ oil is ideally applied every morning and evening on perfectly cleansed and cleansed skin.
Gently massage in with fingertips 1-3 drops (as needed) wheat germ oil in a circular motion until the oil is absorbed.


-Pharmaceutical and medical use:
Many natural vitamin E preparations are made from wheat germ oil and, due to the natural active ingredients it contains, this oil is also commonly used in the production of ointments and powders.
Thanks to its high vitamin E content, wheat germ oil is readily taken orally (against free radicals) and is also considered a dietetic oil.

In addition, the vitamin E contained in Wheat germ oil is important for the gonads to function normally and for a normal pregnancy.
According to Günter A. Ulmer’s book Heilende Öle (healing oils), further positive characteristics of wheat germ oil are that it acts as an anti-inflammatory and protects the cells from premature aging and deterioration.

What is more, the vitamin E within Wheat germ oil can improve the blood flow and oxygen supply of the organs, muscles, and tissues; lead to higher performance and vitality; and guard the heart and circulatory system from damage caused by overstrain.
Vitamin E can also supposedly slow premature aging.

Finally, according to the Lexikon der pflanzlichen Fette und Öle (lexicon of plant fats and oils), a reduction in cholesterol levels in the plasma and liver can be observed in animals.


-Cosmetic use:
Also in the cosmetic area, wheat germ oil has a variety of applications and features several very beneficial characteristics, according to the Lexikon der pflanzlichen Fette und Öle.
For example, Wheat germ oil can be found in skincare and haircare products.

Because of the high percentage of omega-6 fatty acids in the oil, Wheat germ oil is especially well suited for dry and chapped skin.
Wheat germ oil is considered fine skincare oil since it seemingly prevents signs of skin aging; moisturizes the skin; and regulates the metabolism.
Moreover, Wheat germ oil can stimulate cell regeneration in mature and dry skin, which tends to form fine wrinkles.

The vitamin E contained in the oil keeps the connective tissue healthy and makes the skin smooth and elastic.
In addition, Wheat germ oil can also be found in haircare products, where it serves as preventative hair care, to keep the hair healthy and stimulate circulation in the scalp.

In the cosmetic industry, wheat germ oil is also used, for example, in the production of skin oils, powder, soaps, face packs, and other nurturing cosmetics.
Besides this, Wheat germ oil is well suited as a basis for essential oils.

Wheat germ oil and products containing wheat germ oil also offer benefits during pregnancy.
Wheat germ oil is well known that preparations containing vitamin E, when applied percutaneously, improve blood circulation in the peripheral vessels.
For this reason, persons whose skin has poor circulation are advised to apply these products.

Wheat germ oil contains a high percentage of vitamin E.
This makes Wheat germ oil well suited to be mixed into products for perineal massages for pregnant women, so that the vitamin E in the oil improves the tissue’s circulation and elasticity.

Likewise, Wheat germ oil helps strengthen and firm up the connective tissues.
Interestingly, the shelf life of homemade creams can be extended if wheat germ oil is mixed into them.


-In the kitchen:
Cold-pressed wheat germ oil, thanks to its high vitamin E content, can contribute to a healthy diet.
Due to the high amount of tocopherol, Wheat germ oil can also be used as a dietetic oil.
Primarily Wheat germ oil is used to obtain natural vitamin E and unsaturated fatty acids.


-Skin Care uses of Wheat germ oil:
After cleansing your skin, apply Wheat germ oil sufficient amount of oil to your skin via massaging.


-Hair Care uses of Wheat germ oil:
Apply Wheat germ oil sufficient amount of oil by massaging from the roots to the ends, rinse after 15-20 minutes.
You can apply Wheat germ oil twice a week.


-Face uses of Wheat germ oil:
Evening Serum:
Apply Wheat germ oil a thin layer to cleansed skin - especially around the sensitive eye region and on the contours of the lips.


-Anti-aging mask uses of Wheat germ oil:
Apply Wheat germ oil a generous amount to the skin once a week.
Leave on for 15-20 minutes and wipe away with a towel.
A few drops of Wheat germ oil can also be added to a night cream to enhance its nourishing effects.


-Body uses of Wheat germ oil:
Due to the high vitamin E content, wheat germ oil is particularly nourishing for dry skin and offers protection to skin that has been dried out by external factors such as wind, weather, salt, etc.

Wheat germ oil acts as an optimal anti-aging elixir for mature skin.
Wheat germ oil nourishes and restructures the tissue by strengthening the acid mantle and thus counteracting cracking, flaking and irritation.
When blended with sweet almond oil Wheat germ oil ensures improved absorption by the skin.

Massage into moist skin to soften and regenerate very dry, strained as well as flaky skin or skin that has been exposed to the sun for an extended period of time.
In addition, wheat germ oil helps to prevent the formation of stretch marks during pregnancy or breastfeeding.
Even during and after severe weight loss, the oil helps to tighten the skin while also toning and revitalizing tired skin.


-Hair uses of Wheat germ oil:
Wheat germ oil can be used as a treatment before shampooing hair that is extremely dry, bleached, stressed or brittle.
In addition, Wheat germ oil has a positive effect on dry, dehydrated scalp types from the very first application.
Wheat germ oil is appreciated for taking care of the skin, hair and nails.
Wheat germ oil is nourishing, regenerating and helps prevent the signs of aging.



WHEAT / TRITICUM /
A type of grain that belongs to the family of grasses.
It is cultivated almost all over the world, but it comes from south-west and central Asia.
There are about 20 types of wheat, which, apart from barley, is the oldest cultivated grain for over 6,000,000 years.

In the world economy, it ranks third in terms of cereal production.
Common wheat is a common cultivated species.
Fruit called kernels can be used to obtain many raw materials, e.g. wheat germ, from which the extraction process produces a natural oil rich in many ingredients.



NATURAL WHEAT GERM OIL / TRITIUM VULGARE GERM OIL /
Unrefined, cosmetic, cold-pressed oil, 100% obtained from wheat germ.
Rich in proteins, fatty acids and a high content of vitamins A , B, D and E (natural antioxidant).
Wheat germ oil makes the skin smooth and soft.
Wheat germ oil works not only on the skin surface, but easily penetrates the epidermis.

Wheat germ oil is perfect for dry and flaky skin.
Wheat germ oil regenerates the inside of the hair, restores its natural cover and smoothes its surface.
Wheat germ oil protects against excessive water loss and UV radiation.



WHEAT GERM OIL BENEFITS:
Nutritional Value of Wheat Germ Oil:
Wheat germ oil may contain several bioactive compounds like phytosterols, policosanol, lipids, sterols, triterpenols and many more.
Additionally, wheat germ oil may have the following nutrients:

Vitamins present in wheat germ oil:
Vitamin E (alpha-tocopherol)
Vitamin K (phylloquinone)3
Vitamin A (retinol)
Vitamin B1 (thiamin)
Vitamin B2 (riboflavin)
Vitamin B3 (niacin)
Vitamin B5 (pantothenic acid)
Vitamin B6 (pyridoxine)



PROPERTIES OF WHEAT GERM OIL:
Several studies show that wheat germ oil may possess the following properties:
*Wheat germ oil may be an antioxidant.
*Wheat germ oil may have the ability to inhibit the growth of the bacteria.
*Wheat germ oil may have anti-inflammatory properties (may reduce swelling).
*Wheat germ oil may have properties to lower cholesterol levels.
*Wheat germ oil may possess properties to increase the blood flow.
*Wheat germ oil may protect against breast cancer.
*Wheat germ oil may have properties to protect the heart.
*Wheat germ oil may possess wound-healing properties.



HOW TO USE WHEAT GERM OIL?
Wheat germ oil can be added to various food items in the following way:
Wheat germ oil may be added to smoothies, yoghurt, ice cream and cereals.
Wheat germ oil capsules are available in a fixed dose.

Wheat germ oil can be added to pasta or salad as a flavouring agent.
You must consult a qualified doctor before taking any herbal supplements.

Likewise, do not discontinue or replace an ongoing modern medical treatment with an ayurvedic/herbal preparation without consulting a qualified doctor.
Wheat germ oil (WGO) is composed of nonpolar lipids, glycolipids, phospholipids, alcohols, esters, alkene, aldehydes, tocopherols, n-alkanols, sterols, 4-methyl sterols, triterpenols, hydrocarbons, pigments, and volatile components and can be obtained using different techniques



BENEFITS AND HOW TO USE OF WHEAT GERM OIL:
Wheat germ oil is suitable for all skin types, but particularly mature, dry or cracked skin, since it has a high vitamin E content and is rich and nourishing.
Wheat germ oil is a must for the mother to be!

Wheat germ oil is often added in a 10% dilution to other oils as a preservative, and is seldom used on its own because it smells strongly of wheat!
Wheat germ oil keeps for approximately one year.
Wheat germ oils is a pure natural therapeutic quality carrier oil from USA.
Many carrier oils have significant benefit for maintaining a healthy and youthful skin.



WHEAT GERM OIL SKIN BENEFITS:
Wheat germ oil is a nutritiously packed vegetable oil that is believed to have many health benefits.
Wheat germ oil contains in particular oleic and linoleic acids which are soothing for the skin.



EXTRACTION OF WHEAT GERM OIL:
This vegetable oil, Wheat germ oil, is obtained by cold pressing the wheat germ.
Wheat germ oil is rich in antioxidants (vitamin A, D and E), linoleic, oleic acids, lecithin and enzymes.



BENEFITS OF WHEAT GERM OIL:
Very moisturizing, Wheat germ oil stimulates cellular regeneration and the eliminates free radicals.
Wheat germ oil is quickly absorbed into the skin and has excellent firming properties.
Wheat germ oil provides essential nutrients to the skin, which strengthen its defences.



CHARACTERISTICS AND SHELF LIFE OF WHEAT GERM OIL:
Raw Wheat germ oil has a golden yellow to brown hue.
Refined oil, on the other hand, is yellowish.
Wheat germ oil smells like grains and dried herbs and contains weak notes of pepper.

The taste of Wheat germ oil is a typical, distinct wheat taste.
The smoke point of Wheat germ oil is about 90°C.
Wheat germ oil is composed of about 60% polyunsaturated fatty acids, ca. 88% of which is the omega-6 fatty acid linoleic acid.

Additionally Wheat germ oil contains about 18% oleic acid (a monounsaturated fatty acid) and ca. 18% saturated fatty acids (especially palmitic acid).
There are is also ca. 200-300 mg. of vitamin E per 100 grams of oil, giving Wheat germ oilthe highest total vitamin E content of any other oil.
This vitamin E is composed chiefly of alpha-tocopherol.

Moreover, Wheat germ oil has only a limited oxygen stability and can be heated only to about 90°C.
Normal wheat germ oil, when stored in a cool, dark location has a shelf life of 6 months.
If Wheat germ oil has been obtained through extraction, then it has a longer shelf life.



FEATURES OF WHEAT GERM OIL:
Wheat germ oil is remarkable for its unusually high vitamin-E content.
Wheat germ oil provides approx. 233 mg of vitamin E per 100 g of oil and therefore makes an important contribution to the daily diet.
Furthermore, Wheat germ oil has a high proportion of the polyunsaturated fatty acids linoleic acid (omega-6 fatty acid) and linolenic acid (omega-3 fatty acid).



INCREDIBLE BENEFITS OF WHEAT GERM OIL:
Among the extensive range of beneficial oils available in the stores, a member to join the limelight in the recent years is wheat germ oil.
Wheat is no stranger in the Indian household.
While the refined variant - maida - is shunned upon by many, whole wheat flour is lovingly used to make a range of Indian breads like stuffed parathas, fluffy rotis, baturas and the like.

Experts have always said that the nutritional contents of wheat are mostly enclosed in the germ of the grain.
The more the grains are refined, the more we lose the benefits.
Wheat germ refers to the embryo of the seed, which germinates into a plant.

The germ is loaded with essential nutrients such as plant proteins, fiber, vitamins, minerals (phosphorus, zinc, iron, selenium and potassium) and fatty acids which have proven to be beneficial for hair, skin and overall health.
Wheat germ oil is extracted from the germ and is said to be equally as beneficial.



TOP 8 AMAZING BENEFITS OF WHEAT GERM OIL:
Wheat germ oil is the oil obtained from the germ or embryo of wheat.
The germ represents about eight percent of the total weight of the kernel.
Wheat grain is composed of four main parts: bran, endosperm, gluten, and germ.
Bran makes up around 14 percent of the weight of wheat, while germ contributes about eight percent.


Wheat germ Vs wheat bran:
To differentiate between wheat germ vs wheat bran, it is to be noted that wheat bran is the hard, protective outer layer of a whole wheat berry.
It is removed during milling to produce white flour.
Wheat germ is the nutrient-rich embryo of the wheat berry which contains vitamins, minerals, proteins, fats and carbohydrates.
The higher oil content of the germ leads to rancidity if not stored properly.


Components of wheat germ oil:
Wheat contains oil in its germ which is made up of triglycerides and phytosterols.
The triglycerides are broken into fatty acids, which include oleic acid (provitamin A), palmitic acid, linoleic acid (vitamin E), and linolenic acid (omega 3).


What wheat germ oil is good for?
Wheat germ oil has many benefits considering the components it has.
Following are some of the major wheat germ oil benefits that make it highly popular and useful for skin as well as overall health


#1 Anti-ageing
Wheat germ oil is considered to have a high content of omega-6 fatty acids.
Wheat germ oil also has a high antioxidant capacity due to the presence of vitamin E.
Vitamin E prevents oxidation reactions in biological membranes, strengthening them and protecting them from free radicals that cause damage to cells.
Wheat germ oil increases collagen production which leads to younger-looking skin by reducing wrinkles and other signs of ageing.
Wheat germ oil is also used as an emollient in many beauty products because it gives moisture to the skin when applied topically.


#2 Anti-oxidant
It has been discovered that wheat germ oil for skin penetrates into deeper layers of tissues increasing firmness and elasticity while removing toxins from muscles through acupuncture points acting as a detoxifying agent.
This leads to a decrease in signs of aging, such as wrinkles and other fine lines by stimulating collagen production which gives a youthful appearance.


#3 Blood pressure management
A high concentration of alpha-linolenic acid helps reduce blood pressure and increase nitric oxide production, providing your heart a more powerful pump and better circulation throughout your body.


#4 Anti-inflammatory
Wheat germ oil is able to reduce inflammation and ease the painful symptoms of osteoarthritis.
Wheat germ oil can also be used topically for muscle pain relief and itching caused by various conditions such as psoriasis and dermatitis.


#5 Skin Moisturising
Wheat germ oil has a very light texture, which makes it able to be applied directly onto the skin without leaving a greasy residue behind.
Wheat germ oil penetrates easily into the deepest layers of the epidermis and moisturizes without clogging pores or causing allergic reactions.
Wheat germ oil can also regulate moisture levels, soothe irritated skin and restore its natural pH balance.


#6 Nourishment for skin
The antioxidants present in wheat germ oil are able to nourish your skin from deep inside, making it healthier after every application.
Furthermore, Wheat germ oil rejuvenates dead cells on the surface of vital organs by restoring their healthy color and repairing previously existing damage.


#7 Strengthening immune system
Wheat germ oil is rich in several vitamins that are crucial for the proper function of your immune system.
Wheat germ oil contains vitamin E, selenium, magnesium, B1, B6, B12, and folic acid.
These components help maintain optimal health by promoting the growth of new cells, stimulating metabolism processes, and improving overall energy levels.
Regular application can significantly improve stamina and quality of life.


#8 Manages Cholesterol
Octacosanol is a long-chain fatty acid with alcohol that promotes and aids physical performance, including strength and stamina.
According to studies, Octacosanol's capacity to impact fat metabolism, reduce cholesterol production (helps to lower LDL), and prevent hardening of arteries could explain the cardiovascular benefits.

The benefits of Wheat germ oil come mainly from its vitamin E content. Vita-min E possesses antioxidant properties which are helpful for reducing inflammation that may contribute to cardiovascular disease, cancer, rheumatoid arthritis, diabetes, or Alzheimer's disease.
Because it has certain antioxidant compounds known to be important in helping slow down the ageing process, people use it as anti-aging therapy since it works to increase cell membrane integrity and strengthen cells' defense against environmental damage.



HAIR TYPE CONSIDERATIONS OF WHEAT GERM OIL:
Not unlike the most easygoing member of your friend group, wheat germ oil plays well with all hair types and textures, ranging from thick and coily all the way to ultra-fine if you fall into the latter category to avoid weighing down hair.
Naturally dry hair types will respond very well with wheat germ oil.

Wheat germ oil can be used to soften and nourish your hair as often as you need it.
So, in theory, you could opt to do a wheat germ oil hair treatment as often as you choose to lather up.
Those with thinning hair can expect to see stronger follicles with extended use, while thick, natural curls will feel more hydrated.



HOW TO USE WHEAT GERM OIL ON HAIR:
While wheat germ oil is often a hero ingredient found in hair-strengthening formulas, you can also pick up a bottle of the raw, organic, unrefined oil either at your nearest vitamin shop or online to DIY your own treatment.
Using wheat germ oil either alone or as a pre-treatment will produce a balance of added strength and moisture for your hair.

As a Pre-Shampoo Treatment:
Before you lather up, coating your strands from root to tip in wheat germ oil to help soften and nourish your hair.
Let Wheat germ oil sit anywhere from a few minutes to two hours, then rinse out with shampoo.

As a Leave-In Treatment After Shampooing:
Wheat germ oil can also be applied to damp strands while the hair shaft is open.
Applying a few drops from root to end—keeping the “less is more” mantra in mind—and leaving it in as you would with your favorite leave-in conditioner.

To Give Your Conditioner or Mask a Boost:
Want to kick your go-to conditioning treatment up a level?
Adding a few drops to your hair mask or conditioner of choice for an express wheat germ oil treatment.



NUTRITIONAL COMPONENT VALUE OF WHEAT GERM OIL:
Energy 884 kcal
Fats 100 g
Fatty acids (unsaturated) 18.8 g
Fatty acids (monosaturated) 15.1 g
Fatty acids (polyunsaturated) 61.7 g
Choline 20 mg
Vitamin E 149 mg
Vitamin K 24.7 µg
Total carotenoids 12.23 g
Lutein 2.95 g
β- carotene 2.42 g
Other carotenoids 6.89 g
Total steryl ferulate 48.8 g



TYPE OF INGREDIENT:
Hydrator, strengthener, emollient


MAIN BENEFITS:
Wheat germ oil helps to hydrate dry hair, strengthen hair follicles, and boost shine.


WHO SHOULD USE IT:
Wheat germ oil can be used by all hair types ranging from fine to ultra-thick (and everything in between), though dry strands will especially love this ingredient.
While fine hair types can benefit from wheat germ oil, use a lighter hand when applying it to avoid weighing strands down.


HOW OFTEN TO USE IT:
Every time you shampoo your hair to maximize benefits.


WORKS WELL WITH:
In conjunction with your favorite hair mask or conditioner, alongside other carrier oils, or solo as a treatment.


DON'T USE WITH:
While wheat germ oil plays well with most ingredients, those who have a wheat allergy should not use it in their hair routine.



BENEFITS OF WHEAT GERM OIL FOR HAIR:
Want to re-hydrate dry, color-treated strands?
You’ve got it.
Eager to bulk up thinning areas?
Wheat germ oil has you covered.

In dire need of some damage control?
Three words: wheat germ oil.
In addition to being rich in vitamin E and linoleic acid, wheat germ oil is packed with vitamins A, B, and D; squalene; and oleic, palmitic, and linolenic acids, making for an ultra-nourishing cocktail for your hair.


Replaces Lost Moisture:
Thanks to the potent amount of vitamin E in wheat germ oil, wheat germ oil can be used to both boost and maintain moisture levels in dry hair.
The key here is consistency, but with time, your hair will appear shinier and feel less dry.


Repairs Existing Damage:
Since wheat germ oil is loaded with essential fatty acids and vitamins, hair damaged by heat, color, or general environmental stressors will drink in its nourishing, reparative goodness.
In fact, the blend not only repairs existing damage, but actually helps to prevent damage from future styling.


Strengthens Hair Follicles:
While using an oil on thin hair might sound counterintuitive, the vitamin B in wheat germ oil helps to increase circulation to the scalp area and can actually promote new hair growth.
​​People will experience fullness at the crown if they commit to using it consistently, as it does take time for the follicles and root to strengthen.


Creates a Soft, Smooth Finish:
When your hair is healthy and hydrated after a wheat germ oil treatment, it’s almost as if the entire world has fallen into place.
Your fingers flow through your layers a bit easier, curls and waves hold their shape better (and without frizz, at that), and it seems to hold a more glorious, shampoo commercial-esque shine.

The long-chain fatty acids and vitamin E in wheat germ oil have emollient properties to create a softer, smoother finish.
You can expect an increased softness, suppleness, and elasticity when using wheat germ oil.



NUTRITIONAL COMPOSITION OF WHEAT GERM OIL:
The nutritional composition of wheat germ oil per 100g is as follows:
Calories: 884 kcal
Total fat content: 100g
Saturated fatty acids: 18.8 g
Monounsaturated fatty acids: 15.1 g
Polyunsaturated fats: 61.7 g
Choline: 20 mg
Vitamin E: 149 mg
Vitamin K: 27.7 μg
Calories
One hundred grams of wheat germ oil has about 884 kcal. So when you use one tablespoon of wheat germ oil, it will provide 120 Kcal.


Carbohydrates:
Wheat germ oil contains zero carbohydrates, meaning no starch, fibre, or sugar.
Without carbohydrates, the glycemic index of wheat germ oil is also zero.
Zero glycemic index means there’s no effect on blood sugar levels.


Lipids (Fats):
Wheat germ oil is a source of polyunsaturated fatty acids, also regarded as good fat.
Wheat germ oil contains both omega-3 and omega-6 fatty acids.
In addition, Wheat germ oil contains alpha-linolenic acid as well as linoleic acid.

Wheat germ oil also contains healthy monounsaturated fatty acids along with saturated fatty acids.
Wheat germ oil contains eight times more omega-6 (linoleic acid) fatty acids than omega-3 (linolenic acid) fatty acids.
However, Wheat germ oil can also be a downside because omega-3 is healthier than omega-6.


Vitamins and Minerals:
Wheat germ oil provides an alpha-tocopherol form of vitamin E.
A single serving of wheat germ oil can provide 135% of recommended daily vitamin E intake.
Wheat germ oil also contains a small amount of vitamin K used for blood clotting.

While minerals are abundant in wheat germ, most minerals get lost during the oil extraction.
As a result, there are only trace minerals in the wheat germ oil.
Wheat germ oil usually occurs as a by-product in wheat flour production.
Today, modern milling processes for obtaining flour and bran mechanically separate the germ buds, relatively fatty parts of the wheat grains.

For wheat germ oil production, a cold-pressing with a screw press is used, or also an extraction with solvents.
Afterward the oil may possibly undergo refinement.
Furthermore, the wheat germ oil can also be obtained using a solvent-free extraction with supercritical carbon dioxide, which advantageously removes the need for refinement.



HEALTH BENEFITS OF WHEAT GERM OIL:
*Helps Treat Cardiovascular Diseases:
Wheat germ oil contains nutrients that help treat the symptoms associated with cardiovascular disorders.
Wheat germ oil contains phytosterols that reduce cholesterol levels by reducing their absorption.

In addition, the omega-3 fatty acids in wheat germ oil help reduce blood cholesterol levels.
Studies show that omega-3 fatty acid has significantly reduced the mortality risk caused by cardiac arrhythmias and coronary heart diseases.
Wheat germ oil reduces the risks associated with CHD like LDL cholesterol levels and high blood pressure and improves blood circulation.

DHA and EPA omega-3 fatty are excellent cardioprotective agents.
Omega-3 fatty acids in wheat germ oil decrease the levels of serum triglycerides by boosting the degradation of fatty acids.
In addition, reduction in hepatic synthesis of LDL cholesterol also helps reduce triglyceride levels.


*Antioxidant Properties:
Wheat germ oil is a good source of vitamin E, a powerful radical-scavenging antioxidant that helps scavenge free radicals such as lipid oxidation and peroxidation.
Wheat germ oil also contains different forms of vitamin E; tocotrienols and alpha-tocopherols.

Lipid oxidation is a precursor of chronic metabolic disorders such as Alzheimer’s disease, rheumatoid arthritis, and cancer.
Wheat germ oil also helps to improve the immune system.
In addition, vitamin E possesses anti-inflammatory properties that help in easing inflammation.


*Anti-Ageing Properties:
Wheat germ oil contains potent antioxidants which possess anti-ageing activities.
Wheat germ oil delays the progression of anti-ageing signs and symptoms such as dull skin, uneven tone, wrinkles, fine lines, enlarged pores, dry skin, sagging, and dark spots on the skin.

Wheat germ oil has omega-3 fatty acids that possess nourishing and moisturising effects and help treat dry and damaged skin.
Wheat germ oil has a potent antioxidant nutrient, vitamin E that fights against free radicals and prevents oxidative damage.
Wheat germ oil reduces the appearance of wrinkles and scars by stimulating collagen formation between cells.

Wheat germ oil has nourishing and moisturising properties that help in hair growth.
Wheat germ oil stimulates the growth of hair and increases blood circulation in the scalp.
Linoleic and alpha-linolenic acid in wheat germ oil strengthens the hair follicles and restores the moisture content in the hair strands.
Wheat germ oil improves the elasticity of hair strands and adds shine, strength, and softness to the hair.


*Anti-Diabetic Effect:
A study assesses the effects of wheat germ oil on diabetes.
It demonstrated that wheat germ oil significantly reduced the fasting blood glucose, HbA1c, serum lipid profile, serum insulin, and HDL cholesterol levels.
Persistent hyperglycemia increased the production of free radicals in diabetic patients.

Wheat germ oil possesses potent antioxidant activity that scavenges the free radicals and reduces oxidative damage.
The study proved that high doses of wheat germ oil exhibit anti-diabetic, anti-hyperlipidemic, and antioxidant properties.
In addition, Wheat germ oil possesses protective effects against diabetic complications.



FEATURES AND ADVANTAGES OF WHEAT GERM OIL:
*Suitable for all skin types
*Rich in antioxidants
*Strengthening effects



POTENTIAL USES OF WHEAT GERM OIL FOR OVERALL HEALTH:
1. Potential use of wheat germ oil for bacterial infections
Wheat germ oil may possess antibacterial properties.
Wheat germ oil may inhibit the growth of bacteria.

Wheat germ oil may be more sensitive to gram-positive bacteria as compared to gram-negative bacteria (categories based on bacteria that take up staining under the microscope).
However, further studies are yet to be done to check the effect of wheat germ oil on bacterial infections.
If you suspect any symptoms of bacterial infection, you must immediately consult your doctor.


2. Potential use of wheat germ oil for inflammation
Intake of wheat germ oil may be used to reduce swelling.
A study conducted by Harrabi et al. in 2021 showed that bioactive compounds like octacosanol, β-sitosterol and α-linolenic acid might be responsible for the anti-inflammatory property of wheat germ oil.

Wheat germ oil may inhibit cyclo-oxygenase (an enzyme that causes swelling).
However, more studies are required to confirm if wheat germ oil can be used to reduce inflammation.
You must consult your doctor if you experience any symptoms of inflammatory diseases.


3. Potential use of wheat germ oil for hair
Consumption of wheat germ oil may increase blood flow due to the presence of vitamin E.
Increased blood flow in the scalp may help repair the cells in the hair bulb.

Additionally, Wheat germ oil may help reduce hair fall.
However, more studies are needed to check if wheat germ oil is good for hair.
You should consult a doctor for proper treatment if you are facing hair related issues.


4. Potential use of wheat germ oil for skin
Consumption of wheat germ oil may increase the blood flow in the skin, resulting in better supply of nutrients to the skin.
This may be attributed to Wheat germ oil's high vitamin E content.
Wheat germ oil may also have an anti-ageing effect on the skin due to the presence of a bioactive compound, ceramide.

Vitamin E and ceramides may have a moisturising and soothing effect on the skin.
In addition, wheat germ oil may cause skin thickening, which may further help decrease water loss from the skin.
However, more studies are yet to be done to check whether wheat germ oil may benefit the skin.
You must consult your doctor if you see any abnormalities in your skin.


5. Potential use of wheat germ oil for cancer
Oxidative stress is caused by harmful free radicals (molecular particles that harm the body).
In addition, wheat germ oil may reduce tumour size.


6. Potential use of wheat germ oil for wound healing
Wheat germ oil may help to heal wounds.
A study conducted by G.C. Türkoglu et al. in 2021 showed that wheat germ oil might have bioactive compounds that may have properties to work on the skin cells and enhance the wound healing process.

Wheat germ oil may heal burns and wounds due to its high cellular activity and high fluid handling capacity.
However, further studies are yet to be done to check if wheat germ oil may be used to heal wounds.
Therefore, you must consult your doctor if you have a severe wound instead of self-medicating.


7. Potential use of wheat germ oil for lowering cholesterol levels
Antioxidants in wheat germ oil like phenolic acids, flavonoids, tocopherols and carotenoids may help reduce cholesterol levels.
A study by Chadha et al. in 2015 showed that wheat germ oil might lower the bad cholesterol levels- total cholesterol and low-density lipoproteins (LDL).

However, further studies are yet to be done to check if wheat germ oil may be beneficial for lowering cholesterol levels.
Therefore, you must check your cholesterol levels regularly and consult your doctor in case of high cholesterol levels.
Though there are studies that show the benefits of wheat germ oil in various conditions, these are insufficient, and there is a need for further studies to establish the true extent of the benefits of wheat germ oil on human health.



PHYSICAL and CHEMICAL PROPERTIES of WHEAT GERM OIL:
APPEARANCE AT 20°C: Slight viscous clear liquid
COLOR: Pale yellow
ODOR: Nearly odorless
OPTICAL ROTATION (°): 0 / 0
DENSITY AT 20°C (G/ML)): 0,917 - 0,925
REFRACTIVE INDEX ND20: 1,4720 - 1,4760
FLASHPOINT (°C): 261
SOLUBILITY: Insoluble in water
Latin (Botanical) Name: Triticum Vulgare Vill
Plant Family: Poaceae
Extraction Method: Cold press
Plant Part Used: Seed
Color: Orange
Aromatic Description: Strong, raw, grassy aroma
Botanical name: Triticum vulgare
Plant family: Poaceae
Production: Cold Pressed
Cultivation: Conventional cultivation (unaltered & analysed)
Country of origin: USA
Part of plant: Germ
Skincare secret: Skincare
Application : Tinted Moisturisers
For whom: Women
Consistency / Dosage Form: Oil
Scalp Care : Oils
Product Type: Body Oils
Skin Type: Demanding Skin, Mature Skin, Dry Skin
Hair Type: Sensitive Scalp Types , Damaged hair, Dry hair


WHEAT GERM OIL
WHEAT GERM OIL Among the extensive range of beneficial oils available in the stores, a member to join the limelight in the recent years is wheat germ oil. Wheat is no stranger in the Indian household. While the refined variant - maida - is shunned upon by many, whole wheat flour is lovingly used to make a range of Indian breads like stuffed parathas, fluffy rotis, baturas and the like. Experts have always said that the nutritional contents of wheat are mostly enclosed in the germ of the grain. The more the grains are refined, the more we lose the benefits.Wheat germ refers to the embryo of the seed, which germinates into a plant. The germ is loaded with essential nutrients such as plant proteins, fiber, vitamins, minerals (phosphorus, zinc, iron, selenium and potassium) and fatty acids which have proven to be beneficial for hair, skin and overall health. Wheat germ oil is extracted from the germ and is said to be equally as beneficial. "Wheat germ oil (WG) is widely recognised as a nutritious raw material for incorporation into food product formulations or as a food in its own right. Typical applications are in germ-enriched bread, snack foods, and supplements to breakfast cereals, and for production of wheat-germ oil. Wheat germ oil, containing about 8% - 14% oil (average 10%), is mainly used in food, medical and cosmetic industries as a source of oil," as stated in a research paper done by Faculty of Agriculture of Fayoum University, Egypt. Here are a few benefits of wheat germ oil 1. A Rich Source of AntioxidantsWheat germ oil is a great source of Vitamin E, which is said to be a powerful antioxidant. "It helps fight against free radical damage. Coming from the centre of the wheat kernel, wheat germ oil is known for at least 23 odd nutrients, including Vitamins A, B, D and E," says Shonali Sabherwal, a Macrobiotic Nutritionist, Chef and Instructor based in Mumbai. These vitamins all contribute to various functions of the body, particularly skin health. "Vitamin E travels throughout the body neutralising free radicals which would otherwise damage fat-containing structures like cell membranes and brain cells," says Dr. Manoj K. Ahuja, Fortis Hospital. It also helps prevent oxidative stress. 2. A Great Face Cleanser "Wheat germ oil is a natural oil which helps in cleansing the face efficiently. It helps seal moisture back and also gets rid of excess sebum, which could lead to other skin problems like acne, pimples, etc. It does not clog pores as it is non-comedogenic,"says Shilpa Arora, a Health Practitioner, Nutritionist and certified Macrobiotic Health Coach based in New Delhi. A few drops of the oil can be used on your skin or added to your face packs or masks. You can also take a few drops and message gently onto your face and let it rest. Those with oily skin condition must get in touch with a skin care expert before applying the oil. 3. Lowers Cholesterol "It is rich in Octacosanol, which is a long chain fatty acid with alcohol that promotes and aids physical performance, including strength and stamina. Research also shows Octacosanol's ability to affect fat metabolism, decreases cholesterol production (helps to bring down LDL) and prevents hardening of arteries, which could account for the cardiovascular benefits," says Dr. Anju Sood, a renowned Nutritionist based in Bangalore. She further adds, "Wheat germ oil contains the goodness of omega-3 fatty acids, which help in regulating the nervous system systematically." cholesterol 4. Treats Skin Scars Because of its high Vitamin E content, wheat germ oil helps in building collagen, the most abundantly found protein in the body that provides the skin its strength and structure. "The oil repairs, heals and prevents scarring. In fact regular application on scars can completely banish them. Make sure the oil is 100% organic and cold pressed else it will lose most of its nutrients," says Shilpa. "Vitamin A, D and fatty acids present in wheat germ oil help with cracked, scarred skin, giving it an even tone. It also provides natural hydration to the skin," adds Shonali. 5. Acts as a Hair Nourisher Wheat germ oil is a useful ingredient for maintaining healthy hair. "It is rich in linoleic acid and acts as a hair nourisher. Use it in the ratio 10:1 with other carrier oils such as olive and sesame (10 parts carrier oil and 1 part wheat germ oil) and apply on the scalp. Leave it on for some time before rinsing the hair," says Dr Ashutosh Gautam, Clinical Operations and Coordination Manager at Baidyanath. Promoted Listen to the latest songs, only on JioSaavn.com 6. Has Anti-Ageing Properties Being a great source of vitamins - B6, Folic acid and E, wheat germ oil is said to act as an anti-ageing agent for the skin. "Vitamin E is a strong anti-oxidant and it promotes healthy skin as it prevents many skin problems like psoriasis, eczema and dry skin. Vitamin B, on the other hand, helps in repairing tissue damage and promotes tissue growth," adds Dr. Sood. Note: If using wheat germ oil for consumption, it is advisable to do so in little quantities. You can use it to drizzle on to salads or in pastas, but it shouldn't be used for deep-frying. Wheat germ oil is extracted from the germ of the wheat kernel, which makes up only 2.5% by weight of the kernel [1] Wheat germ oil is particularly high in octacosanol - a 28-carbon long-chain saturated primary alcohol found in a number of different vegetable waxes.[2] Octacosanol has been studied as an exercise- and physical performance-enhancing agent. Very long chain fatty alcohols obtained from plant waxes and beeswax have been reported to lower plasma cholesterol in humans.[3] Wheat germ oil is also very high in vitamin E (255 mg/100g), and has the highest content of vitamin E of any food that has not undergone prior preparation or vitamin fortification.[4] As a cooking oil, wheat germ oil is strongly flavored, expensive and easily perishable.[1] Wheat germ oil contains the following fatty acids:[5][6] Other uses of wheat germ oil have also been explored, including increasing blood flow and reaction time.[7] Further uses include treatment of certain skin conditions such as scarring and inflammation.[8] Experience the power of the Mediterranean, Aegean and Black Sea regions in the first truly nutrient-rich skincare fixed oils for women and men alike. Wheat Germ Oil is a highly valuable oil which is difficult to obtain. It is rich in essential fatty acids and Vitamin E. All non-GMO seeds are cultivated naturally, while using gentle, chemical-free, clean cold press methods to ensure pure oils preserve and retain all nutrients, so we can pass them on to you! Description Wheat Germ Oil is a concentrated source of several essential nutrients including Vitamin E, folate (folic acid), phosphor, thiamin, zinc, and magnesium, as well as essential fatty acids and fatty alcohols. Supports the cell membranes of all tissues in the human body, especially those in the nervous system.* Supports the proper function of the cardiovascular system.* Helps protect material in the cell nucleus from free radicals.* Produced from wheat germ oil. Manufactured on equipment that was used to make products containing nuts. Wheat germ oil does not contain gluten. Should not be used in people who are allergic to any of the ingredients. What is wheat germ oil and where can I find it? Wheat germ oil is part of a wheat kernel and is responsible for helping the plant reproduce and spawn new wheat. Although it’s removed from most processed wheat products, it is a major nutritional component of whole grain wheat. Wheat germ oil, along with the husk, is removed from refined wheat products — like those that use white flour — so that they can be stored for longer. Wheat germ oil is added to some granolas, cereals, and cornbread, and it’s also available raw. It is a popular topping for fruit pies, yogurt, ice cream, and hot or cold cereal. It can be a healthier alternative to breadcrumbs in meatballs, meatloaf, and breading for meats. Wheat germ oil is also available in liquid and gelcap form. It can be used as a food additive or as a nutritional supplement. Weight management options have evolved Take our quiz to learn more about techniques and tips that will help you achieve your goals. What can wheat germ oil do for me? Wheat germ oil has excellent nutritional value as a food supplement, experts say. It’s a great source of vegetable proteins, along with fiber and healthy fats. It’s also a good source of magnesium, zinc, thiamin, folate, potassium, and phosphorus. Wheat germ oil is high in vitamin E, an essential nutrient with antioxidant properties. Antioxidants are believed to decrease free radicals in the body, and research suggestsTrusted Source natural sources of antioxidants are best for preventing disease. Some suggest that wheat germ oil can aid in boosting your immunity and help to keep your heart and cardiovascular system healthy. Research suggests that whole grains can reduce the risk of heart disease and help you maintain a healthy weight. According to the European Food Safety Authority (EFSA), there’s enough evidence to suggest that wheat germ oil can help control cholesterol levels. They say, however, that there isn’t enough evidence to back up some other claims, such as suggestions that it can protect the skin against premature aging, help blood pressure, aid in brain function, or aid in digestion. Wheat germ oil and flaxseed have both been used to maintain heart health in menopausal women. Some research suggests that wheat germ oil can also help treat menopausal symptoms, but the research is not conclusive. Avemar, a fermented wheat germ oil extract, is being explored as a treatment for cancer and autoimmune diseases like rheumatoid arthritis. Are there any side effects? People who are gluten intolerant or have gluten allergies should avoid wheat germ oil supplements, as it contains gluten. People who are on a low-carb diet should be mindful of their portion of wheat germ oil, as one cup contains nearly 60 grams of carbohydrates. Wheat germ oil is rich in triglyceridesTrusted Source, a type of fat. People with heart disease, as well as people at a high risk of heart disease, should monitor their intake, as high triglycerides levels are linked with adverse health effects. Wheat germ oil extract can cause mild side effects in some people. These include diarrhea, nausea, gas, and dizziness. You should talk with your doctor about the benefits and risks of adding forms of wheat germ oil into your diet. Wheat germ oil sounds like a healthy product that you should keep in your kitchen. But many consumers keep it in the bathroom. What is wheat germ oil used for? According to many sources, the oil provides beauty benefits.1 Fans of the products use wheat germ oil for hair and skin health. But you can also use it in the kitchen if you choose. Nutrition Facts The following nutrition information is provided by the USDA for one tablespoon of wheat germ oil. Carbs in Wheat Germ Oil There are no carbohydrates in wheat germ oil. That means there is no starch, no fiber, and no sugar (added or naturally occurring) in this product. Wheat germ oil has a glycemic index (GI) of zero, and if consumed, a single serving of the product also has a glycemic load of zero. That means that the food has no effect on your blood sugar levels. As a reference, foods with a GI of 55 or below are considered low glycemic foods. Fats in Wheat Germ Oil The fat in wheat germ oil is what makes this product popular among healthy eaters and beauty buffs. Wheat germ oil provides polyunsaturated fat, considered to be a "good" fat. Polyunsaturated fat is liquid at room temperature and may boost heart health when you use it to replace less healthy fat (like saturated fat) in your diet. There are two different kinds of polyunsaturated fatty acids (PUFAs) and wheat germ oil contains both of them. According to USDA data, you'll get 85 percent (just under 1 gram) of your daily recommended intake of α-linolenic acid (ALA) omega-3 fatty acids. And you'll get 62 percent (7 grams) of your recommended daily intake of linoleic acid or omega-6 fatty acids. You'll also get 2 grams of healthy monounsaturated fat in a single serving of wheat germ oil. You'll also get nearly 3 grams or 12 percent of your recommended daily intake of saturated fat, a fat that is considered to be less healthy. Protein in Wheat Germ Oil There is no protein in wheat germ oil. However, some healthy eaters may use wheat germ oil in marinades, in protein smoothies, or in yogurt to take advantage of the healthy fat that it provides. Micronutrients in Wheat Germ Oil If you consume a single serving of wheat germ oil you'll get 135 percent of your recommended daily intake of vitamin E. This vitamin is an antioxidant that may help neutralize potentially harmful free radicals in the body and provide protective benefits against certain diseases, like prostate cancer or Alzheimer's disease. However, research has provided mixed results, so health experts don't know for sure if consuming more vitamin E is beneficial.2 A single serving also provides a very small amount (4 percent of your recommended daily intake) of vitamin K, a vitamin that is essential for blood clotting purposes in the body. Health Benefits The health benefits of wheat germ oil come primarily from the healthy fat that it provides. However, it is important to remember that all fat—even healthy fat—is energy dense. That means it provides more calories per gram than carbohydrate or protein. While carbs and protein provide just four calories per gram, fat provides nine. So it is important to consume all fats in moderation if your goal is to reach or maintain a healthy weight. Hair and Skin Benefits Beauty buffs also use wheat germ oil to combat hair loss, dandruff, dry skin, wrinkles, lice, and premature aging. To gain the benefits of this oil on the skin and hair, consumers use the product topically. That means, they massage it into the scalp or mix it into conditioners or shampoo to apply to the hair. Unfortunately, however, there is not strong support from the scientific community about the use of wheat germ oil for hair or skin. According to one research review, "After so many years of research on vitamin E, it is still unclear as to whether millions of dollars worth of vitamin E products paid for by patients and consumers have been of any benefit."3 Common Questions What should I look for when purchasing wheat germ oil? Look for a product that has not been bleached or hydrogenated. This may not be an oil that you use very often so look for a smaller container unless you plan to use it often. How should I store wheat germ oil? Store the oil in an air-tight container in your pantry or in another cool dark place. The recommended temperature is 20-25°C or no more than 77 °F. Can I cook with wheat germ oil? Cooking or heating wheat germ oil causes it to lose its nutritional benefits. So frying with wheat germ oil is not recommended. However, you can use the oil in salad dressings, drizzle it on vegetables, pasta, or other dishes for a boost of flavor and omega-3 fatty acids. Recipes and Preparation Tips Because you won't want to cook with wheat germ oil, the uses of the product are somewhat limited. However, some people prefer to use wheat germ oil in salad dressings instead of olive oil. You can also use it as a substitute for other oils when making marinades for fish or meat. If you roast vegetables, you can drizzle wheat germ oil on your veggies after they are done cooking. And some die-hard fans of the oil even add it to smoothies. If you use wheat germ oil for beauty, simply blend a small amount into the skin or hair. Some consumers also blend the oil with other ingredients such as aloe vera or almond oil. Allergies and Interactions According to the Therapeutic Research Center's Natural Medicine's database, you may experience side effects when using wheat germ oil. The source reports that if you consume wheat germ oil in supplement form (orally) the product is usually well tolerated. However, topical use of vitamin E has been associated with contact dermatitis, inflammatory reactions, and other skin reactions. Also, if you are allergic to wheat, you should avoid wheat germ oil. According to the Food Allergy Research and Education Center, symptoms of a wheat allergy reaction can range from mild, such as hives, to severe, such as anaphylaxis. Allergic reactions can be unpredictable, and even very small amounts of wheat can cause one. It is the oil which has been extracted from the germ of wheat kernel. This oil is refined which possess high content of Vitamin E which acts as an antioxidant. It is rich in octacosanol which helps to enhance the physical performance and promotes the muscular energy. It is useful for rejuvenating, moisturizing and protecting mature and drying skin. This cooking oil is easily perishable and expensive. It is loaded with anti-aging and antioxidant properties that helps to prevent the health problems like cardiovascular disease, cancer etc. It also slows down the signs of aging such as wrinkles, fine lines and premature aging signs. Other common names for Wheat germ oil are Wheat oil, Triticum aestivum and Triticum durum. The color of this oil ranges from dark yellow to brown. It possess a heavy odor with nutty aroma. History Wheat plant is inherent to United States but now cultivated in China, North Africa, Southwest Asia, Turkey, Iran, Arabian Peninsula and South Europe. Wheat is one of the ancient grain crops which are known to the human beings. Firstly it was used for making brad since 4000 years ago when the wheat cultivation took place in Nile valley. It was spread across Asia by 4500 and then reached China. In 2000 BC, the wheat cultivation was started by English after it became substantial diet to Chinese and Egyptian civilizations. Nutritional value One cup of 218 grams of Wheat germ oil provides 1927 calories, 325.69 mg of Vitamin E, 218 g of Total lipid fat, 53.8 µg of Vitamin K and 43.6 mg of Choline. The same serving size also provides 40.984 g of total saturated fats, 0.218 g of myristic acid, 36.188 g of palmitic acid, 1.09 g of stearic acid, 32.918 g of total monounsaturated fats, 1.09 g of palmitoleic acid, 31.828 g of oleic acid, 134.506 g of total polyunsaturated fats, 119.464 g of linoleic acid, 15.042 g of linolenic acid and 1206 mg of phytosterols. Health Benefits of Wheat germ oil Wheat germ oil is an excellent source of Vitamin B complex, Vitamin B6, potassium, magnesium, phosphorus and other nutrients. It has high content of nutritional value in comparison to other grains and vegetables. It is composed of about 25% of total nutrients and is loaded with numerous health benefits. This oil has omega-6 acid, palmitic acid, oleic acid, lecithin, squalene and stearic fatty acids. It also possesses lecithin, protein, minerals and essential fatty acids. Due to the richness in minerals and vitamins, it keeps the body healthy from inside. Prevent health ailments Being a great source of Vitamin E, it helps to prevent hair fall, improper metabolic functions and cancer. The intake of Vitamin E or Wheat germ oil helps to avoid these problems. Heart health This oil is very helpful for maintaining heart health. It has good amount of Vitamin B complex that helps to normalize the flow of blood in the body. It has Omega-3 fatty acids that is helpful for maintaining heart health by lowering the cholesterol problems and normalizing the blood pressure. Repairs damage About 28% of protein is available in the wheat germ oil. It provides nutrients to the cells and repairs cell damage. It also assist in transporting vitamins, minerals and nutrients to the cells. Prevents aging process It consists of linoleic acid, phospholipids and Vitamin E that helps to maintain skin health. The application of wheat germ oil helps to prevent wrinkles and other signs of aging. It is a great source of antioxidants that prevents the damage caused by free radicals. Hair health The addition of Vitamin E to the diet helps to get healthy hair. The deficiency of Vitamin E in the body results in dry, rough and weak heair. Wheat germ oil is an excellent source of Vitamin E that helps to enhance the growth of hair and provides a healthy hair. It could be used in the form of capsules, oil or flakes. Provides energy Wheat germ oil has octacosanol which is a long chain, saturated and primary alcohol that helps to promote the muscular energy. It provides oxygen as well as energy while performing exercise so it is useful for sportspersons. Uplifts mood This oil helps to uplift mood due to the presence of Omega-3 fatty acids by regulating the nervous system. It has Vitamin B complex which helps to lower stress. Prevent miscarriage Wheat germ oil helps to prevent the birth defects such as miscarriage and impotence. So it is advised to take wheat germ oil during pregnancy. It also provides healthy red blood cells. Skin ailments Wheat germ oil prevents the skin conditions such as dry skin, eczema and psoriasis. The topical application of this oil helps to repair the skin. Wheat germ oil is used in the production of shampoos, soaps, anti-aging products, moisturizing creams, sunscreen lotions, fairness creams, foot creams and scar treatment products. Due to its moisturizing property, it is used in skin care products. It is combined with other carrier oils in aromatherapy to massage the skin. Wheat germ oil facts Wheat germ oil has been extracted from the germ of wheat kernel. The unrefined oil has high content of essential fatty acids, Vitamin E, regenerative and antioxidant properties. It is sticky, viscous oil having a rich and wheaty odor. Richness in Vitamin E, it possesses regenerative and an antioxidant property that benefits ageing skin and also counteracts free radicals. It has nourishing properties that treats dry skin and assist in forming new skin cells, heals scars and improves circulation. It is highly used as cooking oil which is easily perishable as well as expensive. Unrefined oil has strong aroma and thick consistency. Name Wheat germ oil Wheat germ oil is added in shampoos, soaps, anti-aging products, moisturizing creams, sunscreen lotions, fairness creams etc. It is combined with other carrier oils in aromatherapy. Wheat germ oil is a beneficial oil with a thousand and one virtues. It repairs and soothes injured fears and helps fight against skin aging. Wheat germ oil is the oil that contains the most Vitamin E. Represented by the amount of tocopherols, this vitamin is a powerful "antioxidant". Indeed, it helps fight against free radicals developed during external aggression (pollution, sun exposure, tobacco, etc.). Clearly, the skin is protected, it regains its radiance and youth. In our busy lives, we look for comprehensive solutions that can help us cope with multiple problems. One such very useful solution is wheat germ oil, which is extracted from the kernel of wheat grains. Wheat germ oil is a rich source of vitamin B6 and folic acid of the Vitamin B complex, magnesium, potassium and phosphorus and many other essential nutrients, and is a healthy addition to your diet. Wheat germ oil has a high nutritional value when compared to the other vegetables or grains. It constitutes almost 25% of the total nutrients of the wheat grain and hence is a pack of many health benefits. If you are wondering how it can help you, read on! Benefits Of Wheat Germ Oil: Given below are the top 10 wheat germ oil benefits which will tempt you to start including it in your diet. Wheat germ oil has antioxidant and anti-aging properties, which help in preventing many diseases like cancer, cardiovascular disease, etc. It also helps in reducing the signs of aging like fine lines and wrinkles, and also reduces premature aging signs. It preserves the texture of your skin and hair, and even protects your skin from damage. 2. Reduced Bad Cholesterol It lowers the bad cholesterol levels to a great extent and increases the blood circulation which, in turn, helps in keeping your heart healthy. The increased blood circulation also helps in making the skin and hair healthy. 3. Repairs Tissues Wheat germ oil contains vitamin B, which helps in repairing tissue damage and in tissue growth. It also helps minerals, vitamins and nutrients reach our cells. 4. Boosts Energy Wheat germ oil is high in a long chain, saturated, primary alcohol called octacosanol that improves the muscular energy. Thus, wheat germ oil is highly recommended for sportspersons. It gives energy and oxygen during exercise and makes you energetic too. [ Read: Benefits Of Wheatgrass Juice ] 5. Regulates Nervous System Wheat germ oil is also beneficial in lifting the mood as it contains the goodness of omega-3 fatty acids, which help in regulating the nervous system systematically. It makes you energetic and also reduces the stress to a great extent as it contains vitamin-B complex. 6. Prevents Birth Defects It also prevents many types of birth defects like impotence and miscarriages. It is high in vitamin E. Wheat germ oil is advisable even for pregnant women as it has many benefits and it also prevents birth defects. It also allows healthy red blood cells. 7. Prevents Skin Problems Wheat germ oil helps in providing you with a healthy skin as it prevents many skin problems like psoriasis, eczema, and dry skin. You can apply it topically – it will soothe and repair your skin. It contains vitamin E oil, which is considered to be very good for the skin. 8. Fights Fat Accumulation Wheat germ oil is a fat-fighter and, when used regularly, it helps in reducing the extra fat from the body. It can be part of any weight loss program as it gives you noticeable effects. [ Read: Amazing Benefits Of Almond Oil ] 9. Promotes Blood Sugar Level Wheat germ oil is rich in magnesium. Thus, when used regularly, it helps in promoting healthy blood sugar control, which is especially beneficial for diabetic patients. It helps in keeping the sugar levels under control and thus, controls diabetes to a great extent. 10. Improves Overall Health The regular consumption of wheat germ oil gives you a healthy, long and disease-free life. It prevents many diseases, reduces your stress, and makes you energetic. So, if you want to lead a healthy life, then do include three cups of wheat in your daily diet. Add wheat germ oil to your diet to get all the benefits mentioned above. You can also add it in the following ways: By baking in cookies, breads, waffles, etc. By sprinkling it over ice creams, soups, yogurt, salads, or cereals. Have you tried wheat germ oil ever?? If so, what do you use it for and how has it served you? And, if you’ve tried any of the above, let me know what your experience has been! Here’s Why You Should Use Wheat Germ Oil For Skin Ever tried using wheat germ oil for skin? It may not win a popularity contest among the carrier oils, but it’s worth a try! WHY USE WHEAT GERM OIL FOR SKIN? Wheat germ oil has very high levels of Vitamin E and you know how good that is for your skin! Actually, among all the vegetable oils, wheat germ oil has the highest Vitamin E content. Besides the vitamin, the oil contains fatty acids like linoleic (omega-6), palmitic, and oleic (omega-9) acids. Plus it has vitamins A and D and minerals. That combo is the reason why you should use the oil for skin… they can work magic on dry skin crying out for help… like my cracked heels right now. WHEAT GERM OIL BENEFITS 1. IT IS A GREAT MOISTURIZER Wheat germ oil locks in moisture so it prevents dryness and eases itchy, flaky skin. That makes the oil perfect for elbows, knees and heels. The oil is also great for hair too… Use it to moisturize your hair follicles. 2. VITAMIN E DOES WONDERS Is Vitamin E serum already in your skin care routine? It’s in mine! The vitamin is antioxidant and anti-inflammatory and definitely calms red, angry skin. Actually, take a look at this study from Iran. It found natural remedies like wheat germ oil, flaxseed oil, black seed oil, and violet oil can ease psoriasis symptoms. So, use wheat germ oil to calm psoriasis spots and other inflammatory skin conditions (patch test first though!). 3. IT HELPS WITH BLOOD CIRCULATION I don’t know how. The scientists aren’t so sure either. But they’ve found that massaging wheat germ oil on your skin improves circulation. Maybe it’s because there’s more blood flow to the skin so more oxygen gets in there. Needless to say, the oil leaves your skin looking radiant. Add a little lavender oil too for a great smelling massage blend. Get wheat germ oil: And pin this: Benefits of Wheat Germ Oil for Skin Here’s Why You Should Use Wheat Germ Oil for Skin | #wheatgermoil #carrieroil SKIP THE OIL IF YOU HAVE ACNE There’s this scale for rating vegetable oils that cause acne. It’s called a comedogenic rating. Wheat germ oil has the highest rating – meaning it is likely to cause acne. So, if you have acne prone skin, skip using wheat germ oil. Also, if you have Celiac disease, you should avoid the oil too. Wheat germ oil has gluten in it. I don’t think the oil has gluten, but it’s better to be safe and avoid it if you have gluten allergies. Or patch test to make sure you aren’t reacting to the oil. If you are not acne-prone or sensitive, wheat germ oil will be a great oily friend to your skin… especially during winter! Have you ever used the oil before? I’d love to hear your thoughts! Wheat Germ Oil: But did you know that the ubiquitous cereal grain in pretty much every single Indian kitchen – wheat – also produces an oleaginous residue? Buy Our Top-Selling Wheat Germ Oil Skincare Products And Health Supplements Today, For The Optimal Well-Being Of You And Your Family! Yes, besides being used as atta – the whole wheat flour - to make soft rotis, parathas and bread, as well as maida – the refined powder – to roll fluffy pooris, bhaturas and bake light, moist cakes, the humble grass, in addition, offers wheat germ oil. So What Exactly Is Wheat Germ Oil? Wheat germ oil is essentially the embryo of the seeds, from which the whole crop sprouts. Unlike the refined grain which loses its original nutrient value, the germ portion contains vast reserves of healthful compounds, which are retained in the oil, that is obtained by pressing and extraction processes of the kernels. wheat germ oil benefits for enhanced health Wheat Germ Oil Nutrition Facts: A wonderful gift from Mother Nature, wheat germ oil is a treasure trove of nutritional elements. It comprises significant amounts of healthy fats, plant proteins and fibers, apart from being inherently rich in vitamins E, A, D, K and minerals like potassium, zinc and iron. Moreover, wheat germ oil abounds in potent antioxidant, antimicrobial and anti-inflammatory constituents. Wheat Germ Oil Health Benefits: Lowers LDL Cholesterol Wheat germ oil houses massive quantities of omega 3 fatty acids, which regulate metabolism and lipid breakdown, absorption in the body. This helps to elevate the good HDL cholesterol, while bringing down the bad LDL cholesterol in the bloodstream, thereby minimizing the risk of heart attacks and other associated ailments. It also stimulates cardiac muscle workings and blood circulation in the system. Boosts Energy Capacity The goodness of octacosanol – a long-chain fatty acid with an alcoholic end segment, in wheat germ oil assists in building strength in core muscles, aside from tremendously increasing stamina and resilience. Taking wheat germ oil supplements once a day an hour before a workout immensely bolsters performance in physical activities. Keep in mind to consult with a nutritionist or doctor before consuming nutritive capsules. Slows Down Ageing Wheat germ oil is indeed an elixir for skin wellness. Packed with advantageous antioxidants, apart from the trace mineral zinc, it effectively treats dryness, acne, dark spots, scars and is a superb organic remedy for eczema. Just a few drops of this miraculous tincture is enough, to decrease free radical damage to skin cells, thus diminishing signs of ageing like wrinkles, fine lines and giving a youthful, unblemished appearance. Prevents Hair Fall Infused with ample volumes of vitamin E, along with myriad antimicrobial agents, wheat germ oil is a blessing for a host of hair-related woes. These wholesome components transport vital nutrients to hair roots or follicles, to increase growth, thickness of locks, apart from efficiently getting rid of da
WHEY PROTEIN
White Oil 70#; PARAFFIN OIL, WHITE; PARAFFIN OIL; MINERAL OIL, WHITE; MINERAL OIL; slaboil(obs.); white; whitemineraloil(petroleum) cas no: 8042-47-5
WHITE MINERAL OIL
Wingtack® EXTRA; Wingtack® EXTRA Flake; Wingtack® EXTRA Pastille; Wingtack® EXTRA Molten; WT EXTRA cas no: 62258-49-5
WINGTACK EXTRA
coating integrendt; coated precipitated calcium carbonate ; calcium carbonate cas no: 471-34-1
WINNOFIL SPM
Corn sugar gum; Xanthan; Gum xanthan; Polysaccharide gum; thickener food grade xanthan gum; Petrochemical Xanthan Gum; Tarazine; RHODOPOL 23; XANTHAN; XANTHAN GUM; XANTEMPO™ xanthangumfromxanthomonascampestris CAS NO:11138-66-2
WITCH HAZEL EXTRACT LIQUID
Witch hazel extract liquid is an alcoholic extract from the leaves, flowers and bark of the hamamelis tree.
Witch hazel extract liquid is a great ingredient for use in your cosmetic and medicinal preparations.
Witch hazel extract liquid is well-known for its astringent properties, which help tighten and tone the skin.

CAS Number: 84696-19-5
EINECS number: 283-637-9

Witch hazel extract liquid, contains 20% extract dissolved in water and glycerin.
Witch hazel extract liquid has been found to have anti-irritant and soothing properties.
Witch hazel extract liquid is a natural botanical extract derived from the leaves, bark, and twigs of the witch hazel plant, scientifically known as Hamamelis virginiana.

Witch hazel extract liquid is a popular ingredient in various skincare and cosmetic products due to its astringent and soothing properties.
Witch hazel extract liquid is obtained through a process called steam distillation, where the plant material is heated to release the volatile compounds, which are then condensed to form the liquid extract.
The extract contains several active components, including tannins, flavonoids, and volatile oils, which contribute to its therapeutic effects.

When applied topically, it can help reduce excess oil, minimize the appearance of pores, and temporarily tighten the skin.
Witch hazel extract liquid is often used in facial toners, cleansers, and a variety of skincare products.

Additionally, Witch hazel extract liquid has soothing and anti-inflammatory properties, making it beneficial for various skin conditions such as acne, eczema, and insect bites.
It can help reduce redness, inflammation, and itching, providing relief to irritated skin.

Witch hazel extract liquid can also be used as a natural remedy for minor cuts, scrapes, and bruises.
Its astringent properties can help constrict blood vessels and promote healing.
Witch Hazel Liquid Extract – Standardized is a liquid blend of Witch Hazel extract and Propanediol produced through a unique manufacturing technology.

Witch hazel extract liquid is mild enough to be used alone or Witch hazel extract liquid can be combined with others.
Commercial witch hazel often contains more alcohol than real witch hazel and is distilled only.
Witch Hazel Extract is a plant extract derived from the leaves of the Witch Hazel (Hamamelis Virgi-niana) shrub, that is known for its fragrant winter flowers & woody fruit capsules.

Mainly used as a distillate in soothing and toning products.
Contains 20% extract dissolved in water and glycerin. Found to have anti-irritating and soothing properties. Has skin-cleansing and toning effects.
Plant extract derived from the leaves of the Witch Hazel (Hamamelis Virgi-niana) shrub, that is known for its fragrant winter flowers & woody fruit capsules.

Witch hazel extract liquid is commonly used in skincare products such as toners, cleansers, and facial mists.
Witch hazel extract liquid is believed to help balance oil production, cleanse the skin, and remove excess dirt and impurities.
It is also used as a natural alternative to harsher astringents.

The anti-inflammatory properties of witch hazel extract make it useful in soothing various skin irritations.
It can help calm redness, irritation, and inflammation associated with conditions like acne, dermatitis, razor burn, and sunburn.
Applying witch hazel extract topically can provide a cooling and soothing sensation.

Witch hazel extract liquid contains flavonoids and other antioxidants that help protect the skin from free radicals, which are unstable molecules that can cause damage to cells.
Antioxidants can help neutralize free radicals and reduce oxidative stress on the skin, promoting a healthier complexion.

Witch hazel extract has mild hemostatic properties, meaning it can help constrict blood vessels and reduce bleeding.
It has traditionally been used to help control minor bleeding from cuts, scrapes, and minor wounds.
However, for more severe or deep wounds, it's important to seek appropriate medical attention.

Witch hazel extract liquid is derived from the witch hazel plant, which is native to North America.
It is often marketed as a natural and gentle alternative to synthetic skincare ingredients.
However, it's important to note that some commercially available witch hazel products may contain additional ingredients, so it's always a good idea to check the product label.

Witch hazel extract liquid is generally stable and has a relatively long shelf life when stored properly.
It is typically recommended to store it in a cool, dry place away from direct sunlight.
However, it's always a good idea to check the specific product instructions for storage recommendations.

One of natures best astringents, there is probably no better tonic or toner for skin care preparations.
Witch hazel extract liquid, a clear, yellow to brown extract from organic witch hazel using organic glycerin as the method of extraction.
Witch hazel extract liquid is a distillate prepared from freshly cut and partially dried dormant branches of Hamamelis virginiana.

Witch hazel extract liquid is a natural astringent and has antiseptic, anti-inflammatory, antibacterial and antifungal properties.
Witch hazel extract liquid are deciduous shrubs or (rarely) small trees growing to 3 to 7.5 m tall, even more rarely to 12 m tall.
The leaves are alternately arranged, oval, 5 to 15 cm long, and 2.5 to 10 cm wide, with a smooth or wavy margin.

Witch hazel extract is a clear liquid distilled from the twigs and bark of the witch hazel tree (Hamamelis virginiana).
This beautiful tree flourishes in the Northeastern United States, and the certified organic witch hazel extract that we offer is collected and distilled domestically.

The genus name, Hamamelis, means "together with fruit", referring to the simultaneous occurrence of flowers with the maturing fruit from the previous year.
H. virginiana blooms in September–November while the other species bloom from January–March.
Each flower has four slender strap-shaped petals 1 to 2 cm long, pale to dark yellow, orange, or red.

The fruit is a two-part capsule 1 cm long, containing a single 0.6 cm glossy black seed in each of the two parts; the capsule splits explosively at maturity in the autumn about eight months after flowering, ejecting the seeds with sufficient force to fly for distances of up to 9 m, thus another alternative name "snapping hazel
Witch hazel extract liquid is an alcoholic extract obtained from the leaves and flowers of the witch hazel tree.

Witch hazel extract liquid is a clear, colorless distillate prepared from the leaves of Hamamelis Virginiana.
Witch hazel extract liquid is a natural astringent and has antiseptic, anti-inflammatory, antibacterial and antifungal properties.
A witch hazel liquid soap that provides long-lasting hydration, helps soothe irritated or irritated skin, gently cleanses, deeply moisturizes.

Witch hazel extract liquid acts as an anti-inflammatory and antioxidant substance.
Witch hazel extract liquid is the extract of witch hazel leaves of hamamelis virginiana.
Witch Hazel is native to North America.

Witch hazel extract liquid offers benefits and functions that include enhanced softening, enhanced viscosity, non-irritating properties, outstanding sensory properties, clarity, and anti-bacterial and anti-fungal properties.
The characteristic color of Witch hazel essence liquid fills natural cosmetic formulations with its innate hue.
The colors of the witch hazel extract liquid used to be only artificial, and often artificially obtained.

Objectionable ingredients can now be obtained with plant-based ingredients that not only give their beneficial skin.
Witch hazel extract liquid, health-boosting properties, but also individual natural colors.
Witch hazel extract liquid is an astringent herb that is usually extracted in a mixture of alcoholic water to facilitate complete healing.

Witch hazel extract liquid has a high degree of water solubility as supplied, however, Witch hazel extract liquid is a cloudy-brown solution indicates that the extract will not dissolve completely.
Witch hazel extract liquid contains tannic acid, kaempferol, quercetin and caffeoylquinic acid as active compounds.
The liquid with witch hazel extract has good effects on skin injuries and provides skin toning.

Witch hazel extract is often used as a toner and cleanser for the skin.
It helps remove excess oil, dirt, and makeup residue, leaving the skin feeling refreshed and clean.
Its astringent properties can help tighten pores and reduce the appearance of blemishes.

Witch hazel extract can also be beneficial for scalp and hair care.
Witch hazel extract liquid is believed to help balance the scalp's pH levels, soothe scalp irritation, and reduce dandruff.
It is sometimes used as an ingredient in natural shampoos, conditioners, and hair sprays.

Witch hazel extract's soothing properties make it a popular choice for post-shaving care.
Applying it to the skin after shaving can help calm irritation, reduce redness, and prevent razor bumps.
Witch hazel extract is known for its use in treating hemorrhoids.

Witch hazel extract liquids astringent and anti-inflammatory properties can help reduce itching, swelling, and discomfort associated with hemorrhoids.
It is often available as medicated pads or wipes for convenient application.
In addition to its use for specific skin conditions, witch hazel extract can provide general relief for minor skin irritations like itching, rashes, and insect bites.

Witch hazel extract liquid can help soothe the affected area and alleviate discomfort.
Due to its versatility and gentle nature, witch hazel extract is often used as a natural ingredient in homemade skincare products.
DIY enthusiasts often incorporate it into facial masks, homemade toners, and other formulations.

Witch hazel extract is meant for external use only and should not be ingested.
It is important to avoid contact with the eyes and to keep it out of reach of children.
While witch hazel extract is generally well-tolerated, some individuals may be allergic or sensitive to it.

Witch hazel extract liquid is advisable to perform a patch test on a small area of skin before using it more extensively.
Witch hazel extract liquid is an herbal extract obtained from the leaves of the Witch Hazel (Hamamelis Virgi-niana) bush, namely.

This means that there is no preservative in this ingredient although a suitable preservative should be used when it is combined into a product.
The original color of witch hazel extract liquid is brown to dark brown; but there is a possibility that this color will change, it depends on the formulation it is added to.
Witch hazel extract liquid is a skin soothing agent Native Americans shared with the first European settlers who quickly adopted it.

There are a number of different extraction and distillation methods that various brands use to create witch hazel extract liquid.
Witch hazel extract liquid is a distilled liquid made from dried witch hazel bark, leaves, and relatively inert twigs.
Witch hazel extract liquid is suitable for oily and dry mature skin and contains 86% aqueous witch hazel extract and 14% alcohol that acts as a Preservative.

Witch hazel extract liquid is an alcoholic extract obtained from the leaves and flowers of the witch hazel tree.
However, the organic witch hazel extract line offered by Mountain Rose Herbs is superior in both quality and potency.
Witch hazel extract liquid is distilled from the twigs and bark of the witch hazel tree.

Witch hazel extract liquid is recommended to use Witch hazel extract liquid at a concentration of 1-60%.
Witch hazel extract liquid is soluble in water, alcohol, and glycerol but insoluble in oil.
Witch hazel extract liquid is a clear, colorless botanical extract prepared from dormant plants that are freshly cut and partially dried.

This plant is native to North America, from Nova Scotia in the west to Ontario, Canada and south to Florida and Texas.
Witch hazel extract liquid is obtained by vaporizing the branches of the bush.
Extraction Method: Double distillation with water and organic cane alcohol.

Witch Hazel has been used for treating bruises, a variety of skin problems incoluding dermatitis and acne, haemorrhoids, sunburn, varicose veins and wrinkles.
It is a potent astringent and contains generous amounts of tannins which are excellent for skin conditions.
Studies have suggested it also increases the tone of the blood vessels in the skin which enhances blood supply to damaged areas.

FDA 21 CFR: 347.12
EWG's Food Scores: 1
FDA UNII: 101I4J0U34

Extract from the leaves of the nut bush-like magic tree is often referred to as Witch hazel extract liquid.
Witch hazel extract liquid contains almost no tannins (only 0.04%) and the most active ingredient in the leaves, antibacterial gallic acid.
Witch hazel extract liquid diarrhea, mucous colitis, vomiting blood, coughing up blood, tuberculosis, common cold, fever, tumors and cancer.

Some people apply Witch hazel extract liquid directly to the skin for itching, pain and swelling (inflammation), eye inflammation, skin injury.
Mucous membrane inflammation, varicose veins, hemorrhoids, bruises, insect bites, minor burns and other skin irritations.
In manufacturing, Witch hazel extract liquid leaf extract, bark extract and witch hazel juice are used as astringent to tighten the skin.

They are also included in some medications to give these products the ability to slow or stop bleeding.
These medications are used to treat insect bites, stings, teething, hemorrhoids, itching, irritation, and minor pain.
Free of sulfates, parabens, perfumes and dyes Naturally moisturizing and moisturizing Witch hazel extract liquid is a natural extract also referred to by its botanical name Hamamelis virginiana linné.

Witch hazel extract liquid is 100% naturally distilled, formulated with 14% natural grain alcohol and harvested from a wild plant.
These methods make a big difference in how the final product will affect the skin.
Also, Witch Hazel extract liquid itself is just one of the ingredients it can have when paired with some other natural ingredients.

Besides being an effective natural astringent, Witch Hazel extract liquid is antioxidant and helps to improve the skin barrier.
Most witch hazel extracts are distilled or otherwise extracted using alcohol.
Witch hazel extract liquid works by absorbing moisture from the air and fixing it deep within the skin layers.

Witch hazel extract liquid also works by creating a protective barrier on the skin that helps retain moisture.
Witch hazel extract liquid works by increasing the skin's natural moisture holding capacity to give your skin a beautiful appearance.
The astringent properties of witch hazel extract liquid come from tannins.

The way the Witch Hazel extract liquid in your skin care products is made really makes a big difference in how it will turn out.
Witch hazel is an astringent with anti-inflammatory and antiviral properties. It may help relieve inflammation and fight acne, among other uses.
Witch hazel is a plant with powerful medicinal properties that can be used in a variety of ways.

Witch hazel extract liquid is a liquid distilled from the dried leaves, bark and partially dormant twigs of Hamamelis.
Plant extract derived from the leaves of the Witch Hazel (Hamamelis Virgi-niana) shrub, that is known for it’s fragrant winter flowers & woody fruit capsules.
Witch hazel contains chemicals called tannins.

Witch hazel extract liquid is a clear, colorless distillate prepared from recently cut and partially dried dormant twigs.
This creates a protective coating that increases resistance to inflammation and promotes healing of broken skin.
Witch hazel is a very useful herb for inflammatory and sensitive skin conditions such as eczema.

Witch hazel extract liquid is mainly used in cases where the skin is not significantly broken and helps to protect the affected skin.
Witch Hazel is an alcoholic extract obtained from the leaves, flowers and bark of the witch hazel tree.

Witch hazel extract liquid contains chemicals called tannins.
When applied directly to the skin, witch hazel can help reduce swelling, repair cracked skin and fight bacteria.
Witch hazel extract liquid is a natural alcohol extract derived from Witch tree leaves, flowers or bark extract.

Witch hazel extract liquid is a leathery, deciduous shrub native to the eastern United States.
The bottoms of the leaves are dull gray, and the upward-facing surfaces are bright green.
Witch hazel extract liquid is easy to recognize in the woods in the fall because witch hazel is covered while other trees lose their leaves.

Witch hazel extract liquid is a small tree or shrub belonging to the family Hamamelidaceae.
The Witch hazel extract liquid grows between 1.5 and 3.5 m in height.
The flowers are yellow outside and yellowish brown inside, with four characteristic thread-like petals about 2 cm long.

Witch hazel extract liquid is a liquid distilled from the dried leaves, bark and partially dormant twigs of witch hazel.
Witch hazel extract liquid contains chemicals called tannins.
When applied directly to the skin, witch hazel can help reduce swelling, repair cracked skin and fight bacteria.

One of nature's best astringents, there is probably no better toner or toner for skin care products.
Witch hazel extract liquid is often used in products such as aftershave lotions, and Witch hazel extract liquid looks light.

Witch hazel extract liquid primarily contains polyphenols, including tannins, phenolic acids and flavonoids, and is natural.
Witch hazel extract liquid is a woodland tree native to Canada and the eastern United States.

Witch hazel has been used by Native Americans for centuries against bleeding and inflammation.
Witch hazel extract liquid contains large amounts of tannins.
They have a drying, astringent effect, causing the proteins in the skin and on the surface of abrasions to tighten.

Mainly used as a distillate in soothing and toning products. Contains 20% extract dissolved in water and glycerin.
Witch hazel extract liquid is a leathery, deciduous shrub native to the eastern United States.
The bottoms of the leaves are dull gray, and the upward-facing surfaces are bright green.

Witch hazel extract liquidis easy to recognize in the woods in the fall because witch hazel is covered while other trees lose their leaves.
Witch hazel extract liquid is a clear, colorless distillate prepared from recently cut and partially dried dormant twigs.
Hamamelis virginiana is a shrub native to North America.

Witch hazel extract liquid is distilled from the leaves, flowers and bark of the Hamamelis tree.
One of nature's best astringents, there is probably no better toner and toner for skin care products.

Witch hazel extract liquid is especially beneficial for oily and problematic skin due to its gentle nature.
Plant based Witch Hazel extract liquid is an NPA approved, biodegradable and petrochemical free solvent.

Uses
Witch hazel extract liquid (Hamamelis virginiana)(hamamelis; winterbloom) is traditionally used in the topical treatment of burns, sunburns, skin irritation, insect bites, and bruises.
Witch hazel extract liquid has excellent medicinal properties and is widely used in American folk medicine.
Witch hazel extract liquid can be found in cosmetics, medicine and as part of various herbal tea blends.

Witch hazel extract liquid has powerful anti-inflammatory and anti-oxidation properties that neutralize free radicals and protect your skin against acne, eczema or psoriasis.
Witch hazel extract liquid is especially beneficial for sensitive skin because witch hazel extract liquid can be used for treatment.
Witch hazel extract is widely used as a natural toner to cleanse and tighten the skin.

Witch hazel extract liquid helps remove excess oil, dirt, and impurities while temporarily shrinking the appearance of pores.
Witch hazel extract is a popular ingredient in facial cleansers as it effectively removes dirt, makeup residue, and pollutants from the skin.
It can leave the skin feeling refreshed and clean.

The astringent and anti-inflammatory properties of witch hazel extract make it beneficial for acne-prone skin.
Witch hazel extract liquid can help reduce excess oil, soothe inflammation, and minimize the appearance of blemishes.
Witch hazel extract can provide relief for various skin irritations, such as itching, rashes, and insect bites.

Witch hazel extract liquid has a cooling and soothing effect on the skin, which can help alleviate discomfort.
Witch hazel extract liquid can be applied topically to sunburned skin to help soothe inflammation and reduce redness.
It may provide temporary relief from sunburn symptoms.

Witch hazel extract is commonly used for the relief of hemorrhoids.
Witch hazel extract liquids astringent and anti-inflammatory properties can help reduce itching, swelling, and discomfort associated with hemorrhoids.
Witch hazel extract can be beneficial for scalp health and hair care.

Witch hazel extract liquid can help balance the scalp's pH levels, soothe scalp irritation, and reduce dandruff.
Some people use it as a natural hair rinse or incorporate it into DIY hair care recipes.
Witch hazel extract is often used as an aftershave treatment to soothe the skin and reduce razor burn.

Witch hazel extract liquid can help calm irritation, close pores, and provide a refreshing sensation.
Witch hazel extract has mild antiseptic properties and can be used topically on minor cuts, scrapes, and bruises.
It may help cleanse the wound and promote healing.

Witch hazel extract is a versatile ingredient in DIY skincare products.
Witch hazel extract liquid can be incorporated into homemade facial masks, toners, cleansers, and other formulations.
It is credited with anti-inflammatory, astringent, and wound-healing properties.

Witch hazel extract liquid is often used for its anti-itching, softening, and emollient properties.
Witch hazel extract liquid can also be used in facial toners and spritzes.
Skin and hair care products, facial cleansers, toners, shampoos and conditioners, moisturizers, aftershave and deodorants, antiperspirants.

Antiseptic and astringent properties that cool and soothe the skin great for beauty, hair removal and general first aid use.
Suitable for application after any hair removal, including electrolysis, laser, IPL, nap, waxing, threading.

In addition, anti-free radical activity is now associated with witch hazel, thereby helping counter the damaging effects of uVA, while acting as an absorber of both uVA and uVB.
Witch hazel extract liquid is frequently used in products like after shave lotions, where it shows mildly styptic properties as well as helping to reduce razor burn and swelling through its cool soothing sensation.

Ideal applications for Witch hazel extract liquid are in sun preparations, after-sun preparations, and creams that strive to regenerate overstrained skin.
Personal care applications in both cosmetic and pharmaceutical products.
Witch hazel extract liquid is used in all kinds of ointments, creams, lotions and potions.

Witch hazel extract liquid can also be used in a wide variety of applications such as stings, bites and more.
Witch hazel extract liquid was widely used by early Native Americans for medicinal purposes.
Witch hazel extract liquid can also relieve inflammation, which can be beneficial in reducing scalp irritation.

Witch hazel extract liquid is sometimes used as a natural treatment to treat dandruff and other scalp issues, including scalp issues.
Witch Hazel Distillate regulates oil production, eliminates excess sebum, nourishes, firms, tones, soothes and reduces.
Witch hazel extract liquid is often used as a natural treatment to relieve the discomfort and suffering it causes.

Many people report that witch hazel extract helps with all sorts of ailments, from muscle aches to insect bites.
It can be formulated effectively into gels as an anti-septic preparation for treating impure, greasy skin as well as acne.
Witch hazel extract liquid has been used as an analgesic after postpartum episiotomy or perineal trauma.

Witch hazel extract liquid is sometimes used to heal a sore throat due to its ability to reduce inflammation and serve as a sedative.
Witch hazel extract liquid has been used for a variety of cosmetic applications for over a century.
Witch hazel liquid is widely used for skin care in cleansers and toner products, as well as for hair and body care.

Witch hazel extract liquid is also used in deodorants, aftershave lotions, wet wipes, soaps, creams and other products.
Witch hazel extract liquid is commonly used for dermatological conditions, including diaper-related dermatitis; Still, clinical studies supporting these uses are often lacking.
Witch hazel extract can be used to soothe tired and puffy eyes.

Witch hazel extract can be used to clean and strengthen nails.
It can help remove dirt and residue from the nails and cuticles, and its astringent properties may promote healthier, stronger nails.

Witch hazel extract can be applied topically to sun-exposed skin to help cool and soothe the skin after sun exposure.
Witch hazel extract liquid may provide relief from sunburn discomfort and help prevent peeling.

Witch hazel extract is sometimes used as a natural ingredient in DIY deodorant recipes.
Its astringent properties can help minimize sweat and odor by temporarily tightening the skin.
Witch hazel extract may be used topically to help alleviate discomfort associated with varicose veins.

Witch hazel extract liquids astringent properties can help reduce swelling and improve blood circulation in affected areas.
Witch hazel extract is commonly used by women after childbirth to soothe and provide relief to the perineal area.
It can help reduce swelling and discomfort associated with episiotomies or tearing.

Witch hazel extract, when diluted with water, can be used as a mouth rinse for oral health.
It may help reduce gum inflammation and soothe oral sores.
Witch hazel extract can be used in pet care for various purposes.

Witch hazel extract liquid may help soothe itchy skin, clean minor wounds, or act as a natural ear cleaner for pets.
Witch hazel extract's cleansing properties make it a useful ingredient in homemade cleaning solutions.
It can be added to natural cleaning recipes for surfaces, glass, and more.

The pleasant scent of witch hazel extract makes it suitable for use in aromatherapy.
It can be added to diffusers or used in homemade room sprays to create a calming and refreshing atmosphere.
Some sources cite a recommended dosage of 2 to 5 percent for use in formulations.

Witch hazel extract liquid has been evaluated for uses including analgesic, antiseptic, antioxidant, and antitumor activity.
It is obtained from the leaves and bark of the plant.
Its primary constituents are tannins and saponins. other constituents include volatile oil and gallic acid, with flavonoids also present in the leaves.

Skin Sensitivity:
Some individuals may be sensitive or allergic to witch hazel extract.
It's recommended to perform a patch test on a small area of skin before using it extensively.
If you experience any adverse reactions such as redness, itching, or swelling, discontinue use and consult a healthcare professional.

Eye Contact:
Witch hazel extract should be kept away from the eyes, as it may cause irritation if it comes into direct contact.
If accidental contact occurs, rinse thoroughly with water and seek medical attention if necessary.

Ingestion:
Witch hazel extract is intended for external use only and should not be ingested.
It is not meant to be consumed orally and can be toxic if ingested.
If swallowed, seek immediate medical help or contact a poison control center.

Product Purity:
When purchasing witch hazel extract or products containing it, it's important to ensure the product is of high quality and free from contaminants.
Always buy from reputable sources and check the product's ingredients and manufacturing processes.

Interaction with Medications:
If you are using any topical or oral medications, it's advisable to consult with a healthcare professional before using witch hazel extract.
Some medications may interact with the active components of witch hazel extract, potentially affecting their effectiveness or causing adverse reactions.

Extended Use:
While witch hazel extract is generally safe for short-term use, prolonged or excessive use may cause dryness, irritation, or skin sensitization.
It's best to follow the recommended usage guidelines and consult with a professional if using it for an extended period.

Alcohol Content:
Some commercially available witch hazel extract products may contain alcohol as a preservative.
If you have dry or sensitive skin, alcohol-based formulations may be drying or irritating.

Synonyms
WITCH HAZEL EXTRACT
84696-19-5
hamamelis androgyna leaf oil
hamamelis corylifolia leaf oil
hamamelis dioica leaf oil
hamamelis macrophylla leaf oil
hamamelis virginiana fo. parvifolia leaf oil
hamamelis virginiana fo. rubescens leaf oil
hamamelis virginiana leaf oil
hamamelis virginiana var. angustifolia leaf oil
hamamelis virginiana var. orbiculata leaf oil
hamamelis virginica var. macrophylla leaf oil
hamamelis virginica var. parvifolia leaf oil
trilopus dentata leaf oil
trilopus estivalis leaf oil
trilopus nigra leaf oil
trilopus nigra var. catesbiana leaf oil
trilopus parvifolia leaf oil
trilopus rotundifolia leaf oil
trilopus virginica leaf oil
WITCONATE AOS-12 ALPHA OLEFIN SULFONATE, SODIUM SALT

Sodium Alpha Olefin Sulfonate, known as Witconate AOS-12, is a versatile surfactant widely used in various industries.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is derived from alpha olefins and sulfonated to produce a highly effective cleaning agent.

CAS Number: 68439-57-6
EC Number: 270-407-8

Synonyms: Alpha Olefin Sulfonate, Sodium Salt, AOS, Sodium AOS, AOS-12, Witconate AOS, Witconate AOS-12, Sodium Alpha Olefin Sulfonate, Sodium Alpha-Olefins Sulfonate, Sodium C12-16 Olefin Sulfonate, AOS-40, AOS-30, Sodium C14-16 Olefin Sulfonate, Sodium C14-17 Olefin Sulfonate, Sodium Alkene Sulfonate, Sodium C14-15 Olefin Sulfonate, Alpha-Sulfoalkanes, Sodium Salt, Alpha-Sulfoalkanes, C14-16-Olefin-Sulfonate, Sodium Salt, Olefin Sulfonate, Sodium Salt, Witconate AOS-30, Witconate AOS-40, AOS-23, Sodium C14-15 Olefin Sulfonate, Alpha Olefin Sulfonate, Sodium Salt, Alpha Olefin Sulfonate, Sodium Salt, Liquid, Sodium Olefin Sulfonate, Witconate AOS-23, Alpha Olefin Sulfonate, AOS-12 (Sodium Salt), Alpha Olefin Sulfonate, Liquid, Sodium Salt, Witconate AOS-60, AOS-18, AOS-25, Sodium Alpha-Olefin Sulfonate, Witconate AOS-25, AOS-15, Sodium Alpha-Olefins Sulfonate, Sodium C14-C16 Olefin Sulfonate, Alpha-Olefin Sulfonate, Sodium Salt, Alpha-Olefin Sulfonate, Sodium Salt, Liquid, Alpha-Olefin Sulfonate, Sodium Salt, Solution, Alpha-Olefin Sulfonate, Sodium Salt, 35% Solution, Sodium C12-C14 Olefin Sulfonate, Sodium C14-C16 Olefin Sulfonate, Sodium C14-C17 Olefin Sulfonate, Alpha-Olefin Sulfonate, 35% Solution, Sodium Salt, Alpha-Olefin Sulfonate, Sodium Salt, 40% Solution, Sodium Alpha Olefin Sulfonate, 40% Solution, Sodium Salt, Alpha-Olefin Sulfonate, Sodium Salt, 25% Solution, Sodium C12-C15 Olefin Sulfonate, Sodium C14-C15 Olefin Sulfonate, Sodium C14-C17 Olefin Sulfonate, Sodium Alpha Olefin Sulfonate, 40% Solution, Sodium Salt, Witconate AOS-15, Witconate AOS-18, Witconate AOS-25, Witconate AOS-35, Witconate AOS-40, Witconate AOS-60.



APPLICATIONS


Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is commonly used in the formulation of shampoos to provide effective cleansing and foaming properties.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is a key ingredient in body washes and shower gels, contributing to their ability to remove dirt and oils from the skin.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in liquid hand soaps for its gentle yet efficient cleansing action.

In dishwashing liquids, Witconate AOS-12 helps to cut through grease and food residue, leaving dishes clean and shiny.
Laundry detergents often contain this surfactant to remove stains and dirt from fabrics during the washing process.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to hard surface cleaners to aid in the removal of tough stains and grime from countertops, floors, and other surfaces.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is used in automotive cleaners, including car wash soaps, to effectively clean vehicle exteriors.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is a common ingredient in pet shampoos and grooming products due to its mildness and cleansing properties.

Witconate AOS-12 is employed in industrial cleaning formulations for degreasing and general cleaning purposes.
In agricultural applications, it is used in pesticide formulations to improve spreading and wetting on plant surfaces.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is found in air fresheners and fabric refreshers to aid in odor removal and freshening.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in carpet and upholstery cleaners to lift dirt and stains from fibers without damaging the material.

Witconate AOS-12 is added to foaming bath products such as bubble baths and bath bombs for a luxurious and bubbly bath experience.
In personal care products like facial cleansers and makeup removers, it helps to effectively cleanse the skin without stripping away natural oils.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is incorporated into shaving creams and gels to provide lubrication and foam for a smooth shave.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is used in hand sanitizers and antibacterial soaps for its ability to create a lather and aid in cleansing.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to hair styling products such as mousses and gels to enhance texture and provide hold.

In textile processing, it is used as a wetting agent to aid in the penetration of dyes and chemicals into fabrics.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is employed in the formulation of foaming cleansers for use in the foodservice industry.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to industrial degreasers and cleaners for cleaning equipment and machinery in manufacturing facilities.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is used in the formulation of household and industrial floor cleaners to remove dirt and stains from floors.

In carpet shampoo formulations, it helps to loosen dirt and debris from carpet fibers for easier removal.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in boat and marine cleaners to remove salt residue and other debris from surfaces.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is found in leather cleaners and conditioners to help clean and moisturize leather surfaces.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt has a wide range of applications across various industries, contributing to the effectiveness and performance of numerous cleaning and personal care products.

In the cosmetics industry, Witconate AOS-12 is used in facial cleansers, makeup removers, and exfoliating scrubs to effectively cleanse and refresh the skin.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to bath salts and bath bombs to enhance foaming and create a luxurious bathing experience.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in hand cleaners and sanitizers for its ability to create a rich lather and cleanse hands effectively.
In the pharmaceutical industry, it is used in the formulation of medicated shampoos and body washes for treating various skin conditions.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is incorporated into foot care products such as foot scrubs and creams to cleanse and soften the skin.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to mouthwash formulations to aid in the removal of bacteria and plaque from the mouth.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is used in the manufacturing of liquid soaps and hand washes for institutional and commercial settings.
In the hospitality industry, it is found in hotel amenities such as shampoo, conditioner, and body wash.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is employed in the formulation of baby care products such as baby shampoos and body washes for gentle cleansing.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is used in the production of pet care products such as pet shampoos and grooming sprays for maintaining pet hygiene.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to facial cleansing wipes and makeup remover wipes for convenient and effective makeup removal.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in the formulation of acne treatment products such as facial cleansers and spot treatments for their cleansing and antibacterial properties.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is found in sun care products such as sunscreens and after-sun lotions for its emulsifying and moisturizing properties.
In the automotive industry, it is used in car wash detergents and degreasers for cleaning vehicle exteriors and engines.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is employed in the formulation of industrial hand cleaners and degreasers for removing heavy soils and grease.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to metal cleaners and polishes for removing tarnish and restoring shine to metal surfaces.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in the production of household disinfectants and sanitizers for cleaning and disinfecting surfaces.

In the agriculture industry, it is used in the formulation of agricultural adjuvants to improve the efficacy of pesticides and herbicides.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is found in air freshener sprays and room deodorizers for neutralizing odors and freshening the air.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to household cleaning wipes and disposable cleaning cloths for convenient and effective cleaning on-the-go.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is employed in the production of industrial degreasing wipes and industrial cleaning cloths for heavy-duty cleaning applications.

In the construction industry, it is used in the formulation of concrete cleaners and masonry cleaners for removing dirt and stains from surfaces.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is added to rust removers and corrosion inhibitors for protecting metal surfaces from rust and corrosion.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is utilized in the formulation of electronic cleaning solutions and contact cleaners for removing dust and debris from electronic components.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt has diverse applications across various industries, contributing to the effectiveness and performance of a wide range of cleaning and personal care products.



DESCRIPTION


Sodium Alpha Olefin Sulfonate, known as Witconate AOS-12, is a versatile surfactant widely used in various industries.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is derived from alpha olefins and sulfonated to produce a highly effective cleaning agent.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is available in different forms including liquids and powders.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt exhibits excellent foaming properties, making it ideal for applications where foam stability is desired.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is commonly used in personal care products such as shampoos, body washes, and liquid soaps.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt provides gentle cleansing while producing rich and luxurious lather.
In household cleaning products, it is used in dishwashing liquids, laundry detergents, and hard surface cleaners.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt effectively removes dirt, grease, and stains from various surfaces.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is biodegradable, making it environmentally friendly compared to some other surfactants.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt performs well in both hard and soft water conditions without losing effectiveness.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is compatible with a wide range of pH levels, enhancing its versatility in formulation.
Its mildness makes it suitable for use in personal care products, even for sensitive skin types.
In industrial applications, Witconate AOS-12 is used in car wash products and oilfield chemicals.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt helps in the removal of tough stains and provides excellent cleaning performance.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is stable under normal storage conditions, but should be protected from extreme temperatures and moisture.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is easy to handle and can be incorporated into formulations with ease.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is anionic in nature, meaning it carries a negative charge, which enhances its ability to remove dirt and grease from surfaces.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is often used in combination with other surfactants and ingredients to optimize performance.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is compatible with most other commonly used ingredients in cleaning and personal care formulations.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt undergoes rigorous quality control measures to ensure consistency and purity.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is produced using advanced manufacturing processes to meet the highest industry standards.
Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is packaged and labeled according to regulatory requirements to ensure safe handling and use.

Witconate AOS-12 Alpha Olefin Sulfonate, Sodium Salt is widely available from various suppliers and distributors around the world.
Its versatility, effectiveness, and mildness make it a preferred choice for formulators across different industries.
Sodium Alpha Olefin Sulfonate, Witconate AOS-12, continues to be an essential ingredient in numerous household, personal care, and industrial products, contributing to their cleaning efficacy and consumer satisfaction.



PROPERTIES


Appearance: Clear to slightly yellow liquid or white powder.
Odor: Mild characteristic odor.
Melting Point: Typically does not have a specific melting point as it exists as a liquid or powder.
Boiling Point: Decomposes before boiling; decomposition temperature depends on the specific composition and purity.
Density: Varies depending on concentration and formulation; typically ranges from 1.0 to 1.2 g/cm³ for liquids.
Solubility in Water: Soluble in water, producing a clear or slightly cloudy solution.
Solubility in Other Solvents: Insoluble in non-polar solvents such as hydrocarbons, but soluble in polar organic solvents.
pH: Typically alkaline; pH ranges from 7 to 10 in aqueous solutions, depending on concentration.
Flash Point: Not applicable for aqueous solutions; may have flash points for concentrated solutions in organic solvents.
Viscosity: Varies depending on concentration and temperature; typically low viscosity for aqueous solutions.
Chemical Properties:
Chemical Formula: Typically represented as R-CH=CH-(CH2)n-SO3Na, where R represents an alkyl group and n represents the number of carbon atoms in the chain.
Molecular Weight: Varies depending on the specific alkyl chain length and sulfonation degree.
Functional Groups: Contains a sulfonate (SO3) group attached to an olefinic carbon chain.
Ionization: Anionic surfactant; dissociates in water to form sodium ions (Na+) and sulfonate ions (SO3-) in solution.



FIRST AID


1. Inhalation:

Symptoms:
Inhalation of aerosolized or vaporized particles may cause irritation to the respiratory tract, including coughing and difficulty breathing.

Immediate Actions:
Remove the affected person to fresh air immediately.
If breathing is difficult, provide oxygen if available.
Seek medical attention if symptoms persist or worsen.

Follow-Up:
Monitor the person for any signs of respiratory distress.
Provide comfort and reassurance.


2. Skin Contact:

Symptoms:
Direct contact with concentrated solutions may cause irritation, redness, or dermatitis.

Immediate Actions:
Remove contaminated clothing and shoes.
Wash the affected area thoroughly with soap and water for at least 15 minutes.
If irritation persists, seek medical attention.

Follow-Up:
Apply a mild moisturizing cream or lotion to soothe the skin.
Monitor for any signs of allergic reactions or prolonged irritation.


3. Eye Contact:

Symptoms:
Contact with the eyes may cause irritation, redness, or tearing.

Immediate Actions:
Rinse the eyes immediately with gently flowing water for at least 15 minutes, while holding the eyelids open.
Remove contact lenses if present and easily removable.
Seek medical attention if irritation persists or if there is any evidence of injury.

Follow-Up:
Protect the affected eye from further irritation or injury.
Avoid rubbing the eyes, as this may exacerbate irritation.


4. Ingestion:

Symptoms:
Ingestion of concentrated solutions may cause gastrointestinal irritation, nausea, vomiting, or diarrhea.

Immediate Actions:
Do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth with water and drink plenty of water or milk to dilute the chemical.
Seek medical attention immediately, even if symptoms are not present.

Follow-Up:
Monitor the person for any signs of gastrointestinal distress or discomfort.
Provide supportive care as necessary, such as antiemetics for nausea and vomiting.


5. General Advice:

Personal Protection for First Aiders:
Wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing when handling concentrated solutions.
Avoid direct skin and eye contact with the chemical.

Notes to Physician:
Treat symptomatically and supportively.
Provide appropriate medical treatment based on the severity of symptoms and exposure.
Be aware of potential interactions with other medications or chemicals.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE), including chemical-resistant gloves, safety goggles, and protective clothing, when handling concentrated solutions.
Use respiratory protection, such as a dust mask or respirator, if aerosolized particles or vapors are present.
Avoid prolonged or repeated skin contact with concentrated solutions to minimize the risk of irritation.

Safe Handling Practices:
Handle Sodium Alpha Olefin Sulfonate with care to prevent spills or releases.
Use suitable tools and equipment, such as pumps or transfer hoses, to minimize direct contact with the chemical.
Do not eat, drink, or smoke while handling the chemical, and wash hands thoroughly after handling.

Engineering Controls:
Ensure adequate ventilation in the work area to minimize exposure to airborne particles or vapors.
Use local exhaust ventilation systems or fume hoods when working with concentrated solutions to control exposure levels.

Hygiene Measures:
Provide facilities for washing hands and body promptly after handling Sodium Alpha Olefin Sulfonate.
Avoid contamination of eating and drinking areas with the chemical.
Launder work clothing regularly to prevent skin irritation from residual chemical exposure.

Spill Prevention:
Store containers of Witconate AOS-12 securely to prevent tipping or accidental spills.
Use secondary containment systems, such as spill trays or bunds, to contain spills and prevent environmental contamination.
Train personnel on proper spill response procedures and provide spill cleanup materials.


Storage:

Storage Conditions:
Store Sodium Alpha Olefin Sulfonate in a cool, dry, well-ventilated area away from direct sunlight and sources of heat.
Maintain storage temperatures within recommended ranges to prevent degradation or crystallization.
Ensure storage facilities are equipped with appropriate temperature and humidity controls, especially for powdered forms of the chemical.

Container Handling:
Use containers made of compatible materials, such as high-density polyethylene (HDPE) or stainless steel, for storing Witconate AOS-12.
Check containers for leaks or damage before storing and handle with care to avoid spills or accidents.
Label all containers with the chemical name, concentration, hazard warnings, and handling precautions.

Segregation:
Store Sodium Alpha Olefin Sulfonate away from incompatible substances, such as strong acids, bases, oxidizing agents, and reactive metals.
Segregate different chemical classes to prevent cross-contamination and chemical reactions.

Inventory Management:
Implement a first-in, first-out (FIFO) inventory system to ensure older stocks are used before newer ones.
Keep accurate records of inventory levels and consumption to prevent overstocking or shortages.

Security Measures:
Restrict access to storage areas containing Witconate AOS-12 to authorized personnel only.
Implement security measures, such as locked cabinets or access controls, to prevent unauthorized access or theft.

Emergency Preparedness:
Develop and maintain emergency response plans for handling spills, leaks, or accidents involving Sodium Alpha Olefin Sulfonate.
Ensure personnel are trained on emergency procedures and have access to emergency response equipment, such as spill kits and personal protective gear.
WOOL WAX
Wool wax consists mainly of long-chain waxy esters or sterol esters that do not contain glycerides.
Wool wax is used in the protection, treatment and cosmetic improvement of human skin.
Wool wax is used as an active ingredient in over-the-counter topical products such as ointments, lubricants, lotions, and facial cosmetics.

CAS Number: 8006-54-0
EC Number: 232-348-6

Synonyms:
Lanolin, 8006-54-0, 7EV65EAW6H, Anhydrous lanolin, Wool grease, Wool wax, refined, Black Rose, Lanashield, Lanolin, anhydrous, Skin Protectant with Lanolin, Theresienol MD Skin Protectant, Theriac Advanced Healing, 232-348-6, 3CE DRAWING LIP CHILLING, 4sport skincare anti chafing, AGNOLIN NO 1, AmeriDermDermaFix, CORONA MULTI-PURPOSE, CORONA ORIGINAL LANOLIN RICH, DTXSID2027678, EMERY 1600, EUCERITE, LANOLIN (II), LANOLIN (USP MONOGRAPH), LANOLIN (USP-RS), LANOLIN,ANHYDROUS LIQUID, Lana1263, LanoGuardDaily Care Skin Protectant, LanoGuardDry Skin Therapy, Lanoderm, Lantiseptic Dry Skin Therapy, Lantiseptic by DermaRite Original Skin Protectant, Lantiseptic by Dermarite Dry Skin Therapy, LincoFix, North Country Dairy Supply Non Iodine Barrier Dip, PrimaGuardDaily Care Skin Protectant, SUINTINE, Smartchoices Lanolin Plus0, Soothe and Cool Free Medseptic, Soothe and Cool Free MedsepticSkin Protectant

Wool wax (from Latin lāna 'wool', and oleum 'oil'), also called wool fat, wool yolk, wool grease or Lanolin, is a wax secreted by the sebaceous glands of wool-bearing animals.
Wool wax used by humans comes from domestic sheep breeds that are raised specifically for their wool.
Historically, many pharmacopoeias have referred to Wool wax as wool fat (adeps lanae); however, as Wool wax lacks glycerides (glycerol esters), it is not a true fat.

Wool wax primarily consists of sterol esters instead.
Wool wax's waterproofing property aids sheep in shedding water from their coats.
Certain breeds of sheep produce large amounts of Wool wax.

Wool wax is a principle component of Wool wax, which is a natural product obtained from the fleece of sheep.
Wool wax is found in steroid-containing creams/ointments, medicated shampoos, veterinary products, hand lotions, moisturizers, sunscreens, self-tanning creams, lipsticks, makeup removers, foundations, eye shadows, hairsprays, shaving creams, baby oils and products, printing inks, furniture and shoe polishes, lubricants, leather, and paper.

Wool wax's role in nature is to protect wool and skin from climate and the environment.
Wool wax also plays a role in skin (integumental) hygiene.
Wool wax and its derivatives are used in the protection, treatment, and beautification of human skin

Wool wax is a yellow fat obtained from sheep's wool.
Wool wax is used as an emollient, cosmetic, and pharmaceutic aid.
The US federal code of regulations states that Wool wax in the concentration range of 12-50% may be included in over the counter skin ointments.

Wool wax is the purified, secreted product of the sheep sebaceous glands.
Wool wax primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides.
For this reason, Wool wax is also called Lanolin or wool grease.

Wool wax is used in the protection, treatment, and cosmetic enhancement of human skin.
Wool wax hydrophobic properties can help protect skin against infections or skin irritation, as Wool wax helps seal in moisture that is already present in the skin.

Wool wax is used as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and facial cosmetics.
Wool wax is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding mothers,.

Wool wax is a yellow fat obtained from sheep's wool.
Wool wax is used as an emollient, cosmetic, and pharmaceutic aid.

The US federal code of regulations states that Wool wax in the concentration range of 12-50% may be included in over the counter skin ointments.
Wool wax is the purified, secreted product of the sheep sebaceous glands.

Wool wax primarily consists of long-chain waxy esters, or sterol esters, that lack glycerides.

Wool wax is used in the protection, treatment, and cosmetic enhancement of human skin.
Wool wax hydrophobic properties can help protect skin against infections or skin irritation, as Wool wax helps seal in moisture that is already present in the skin.

Wool wax is used as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and facial cosmetics.
Wool wax is also frequently used in protective baby skin treatment and for sore nipples in breastfeeding mothers.

Wool wax is a waxy substance that sheep naturally produce to protect their wool.
Because Wool wax's properties are similar to those of the sebum (oil) secreted by human skin, Wool wax is a popular ingredient in moisturizers, hair care products, and soaps.
Wool wax is also widely promoted as a natural remedy for sore nipples due to breastfeeding.

The Wool wax in the products you buy comes from sheep raised for their wool.
Wool wax also goes by the names wool grease, wool yolk, and Lanolin.

Wool wax oil is a secretion from sheep’s skin.
Wool wax is similar to human sebum, an oil secreted by the sebaceous glands that you may notice particularly on your nose.

Unlike sebum, Wool wax contains no triglycerides.
Wool wax is sometimes referred to as “wool fat,” but the term is misleading because Wool wax lacks triglycerides needed to be considered a fat.

The purpose of Wool wax is to condition and protect sheep’s wool.
This conditioning property is why the substance is now widely used in human cosmetics, skin care, and hair products.

Wool wax oil is extracted by putting sheep’s wool through a centrifuge machine that separates the oil from other chemicals and debris.
The process is performed after the sheep is sheared so the extraction of Wool wax causes no harm to sheep.

You may already be using products that contain Wool wax oil without realizing Wool wax.
Many medicine cabinet staples including lip balms, lotions, and nipple creams contain the amber-colored substance loved for Wool wax moisturizing ability.

Wool wax is a waxy substance derived mainly from the wool of sheep.
The sheep’s sebaceous glands produce this “wool wax” to help shed water and keep the sheep dry.
Wool wax is extracted by putting the wool through a centrifuge machine that separates the oil from other chemicals and debris.

Growing Popularity of Wool wax:
Wool wax is used in an array of products like pharmaceuticals, leather, textiles, baby and men’s care products, bio-lubricants, and nearly all types of cosmetics marketed to women.
While pharmaceutical-grade Wool wax is the lion’s share of the market today, the growing demand for natural and organic ingredients in personal care products is driving Wool wax market growth, which is expected to be worth more than $450 million USD by 2024.

In beauty products, specifically, Wool wax gives lipsticks heavy gloss and high-shine.
Formulations like these are about 5-10% Wool wax by weight.

Wool wax may also appear in cosmetics as modified versions of Wool wax oil.
Lanfrax, for instance, is the trade name of a Wool wax oil compound that has polyethylene glycol attached to Wool wax to make it more water-soluble.
Accounting for these modified versions of Wool wax, Wool wax and its derivatives may account for approximately 15-25% of the weight of a given lipstick.

So, though the production of Wool wax seems innocent enough because the process happens after the sheep are shorn, and seems like Wool wax should be a natural byproduct of the wool industry, Wool wax is a major industry of its own.
The only way to sustain the accelerating levels of Wool wax production is by being inextricably linked to mass-produced wool, which is a slaughter industry with inhumane practices.
Because the Wool wax industry relies directly on mass-produced wool, Wool wax also supports cruelty.

Composition of Wool wax:
A typical high-purity grade of Wool wax is composed predominantly of long chain waxy esters (approximately 97% by weight) with the remainder being Wool wax alcohols, Wool wax acids and Wool wax hydrocarbons.
An estimated 8,000 to 20,000 different types of Wool wax esters are present in Wool wax, resulting from combinations between the 200 or so different Wool wax acids and the 100 or so different Wool wax alcohols identified so far.

Wool wax’s complex composition of long-chain esters, hydroxyesters, diesters, Wool wax alcohols, and Wool wax acids means in addition to its being a valuable product in Wool wax own right, Wool wax is also the starting point for the production of a whole spectrum of Wool wax derivatives, which possess wide-ranging chemical and physical properties.
The main derivatisation routes include hydrolysis, fractional solvent crystallisation, esterification, hydrogenation, alkoxylation and quaternisation.
Wool wax derivatives obtained from these processes are used widely in both high-value cosmetics and skin treatment products.

Hydrolysis of Wool wax yields Wool wax alcohols and Wool wax acids.
Wool wax alcohols are a rich source of cholesterol (an important skin lipid) and are powerful water-in-oil emulsifiers; they have been used extensively in skincare products for over 100 years.

Approximately 40% of the acids derived from Wool wax are alpha-hydroxy acids (AHAs).
The use of AHAs in skin care products has attracted a great deal of attention in recent years.
Details of the AHAs isolated from Wool wax can be seen in the table below.

Production of Wool wax:
Crude Wool wax constitutes about 5–25% of the weight of freshly shorn wool.
The wool from one Merino sheep will produce about 250–300 ml of recoverable wool grease.

Wool wax is extracted by washing the wool in hot water with a special wool scouring detergent to remove dirt, wool grease (crude Wool wax), suint (sweat salts), and anything else stuck to the wool.
The wool grease is continuously removed during this washing process by centrifuge separators, which concentrate Wool wax into a waxlike substance melting at approximately 38 °C (100 °F).

Applications
Wool wax and its many derivatives are used extensively in both the personal care (e.g., high value cosmetics, facial cosmetics, lip products) and health care sectors such as topical liniments.
Wool wax is also found in lubricants, rust-preventive coatings, shoe polish, and other commercial products.

Wool wax is a relatively common allergen and is often misunderstood as a wool allergy.
However, allergy to a Wool wax-containing product is difficult to pinpoint and often other products containing Wool wax may be fine for use.

Patch testing can be done if a Wool wax allergy is suspected.
Wool wax is frequently used in protective baby skin treatment and for sore nipples from breastfeeding although health authorities do not recommend it, advise against nipple cleaning and rather recommend improving baby positioning and expressing milk by hand.

Wool wax is used commercially in many industrial products ranging from rustproof coatings to lubricants.
Some sailors use Wool wax to create slippery surfaces on their propellers and stern gear to which barnacles cannot adhere.

Commercial products (e.g. Lanocote) containing up to 85% Wool wax are used to prevent corrosion in marine fasteners, especially when two different metals are in contact with each other and saltwater.
The water-repellent properties make Wool wax valuable in many applications as a lubricant grease where corrosion would otherwise be a problem.

7-Dehydrocholesterol from Wool wax is used as a raw material for producing vitamin D3 by irradiation with ultraviolet light.
Baseball players often use Wool wax to soften and break in their baseball gloves (shaving cream with Wool wax is popularly used for this).

Anhydrous liquid Wool wax, combined with parabens, has been used in trials as artificial tears to treat dry eye.
Anhydrous Wool wax is also used as a lubricant for brass instrument tuning slides.

Wool wax can also be restored to woollen garments to make them water and dirt repellent, such as for cloth diaper covers.
Wool wax is also used in lip balm products such as Carmex.

For some people, Wool wax can irritate the lips.
Wool wax is sometimes used by people on continuous positive airway pressure therapy to reduce irritation with masks, particular nasal pillow masks that can often create sore spots in the nostrils.

Wool wax is a popular additive to moustache wax, particularly 'extra-firm' varieties.
Wool wax is used as a primary lubricating component in aerosol-based brass lubricants in the ammunition reloading process.

Mixed warm 1:12 with highly concentrated ethanol (usually 99%), the ethanol acts as a carrier which evaporates quickly after application, leaving a fine film of Wool wax behind to prevent brass seizing in resizing dies.
Wool wax, when mixed with ingredients such as neatsfoot oil, beeswax and glycerol, is used in various leather treatments, for example in some saddle soaps and in leather care products.

Products That May Contain Wool wax:

Cosmetics:
Foundations
Eye makeup
Lipsticks

Hair Care:
Hairspray

Household Products:
Furniture polish
Leather
Paper
Printing inks

Liquids:
Baby oils
Baby ointments
Hand lotion
Moisturizers
Self-tanners
Sunscreen

Benefits of Wool wax:
Wool wax is classified as an occlusive moisturizer.
This means Wool wax works by reducing water loss from the skin, similar to petroleum jelly.

While petroleum can reduce the evaporation of skin's moisture by 98%, Wool wax reduces it by between 20% and 30%.
However, many people like that Wool wax isn't as heavy as petroleum jelly, making Wool wax more pleasant to use.

In skincare products, there's no hard evidence showing Wool wax is better than synthetic waxes.
If you like using natural products, though, you may prefer Wool wax over synthetics.

Wool wax is in a wide variety of over-the-counter (OTC) products.

They include:
Eye creams
Hemorrhoid medication
Lip balm
Lotions and creams for dry skin
Makeup and makeup removers
Medicated shampoos
Mustache wax
Shaving cream
Baby oil
Diaper rash cream

Wool wax for Breastfeeding and Sore Nipples:
During breastfeeding, your nipples may become sore, dry, and even cracked.
Many healthcare providers recommend Wool wax creams to ease nipple pain from breastfeeding.

A big benefit is that it's generally considered safe for your baby to ingest small amounts of Wool wax.
Wool wax 's recommended that you use it at least ten minutes before you start breastfeeding.
But unlike other products, you don't need to wipe Wool wax off.

Wool wax 's also safe to give your baby breastmilk expressed while Wool wax is on your nipples. (Again, wait about 10 minutes after application before you begin pumping.)

Research into Wool wax for nipple pain has been mixed.

A 2018 Brazilian study suggested significant improvements in nipple pain and trauma in participants who used Wool wax compared to those who rubbed in breastmilk (another common remedy for nipple soreness).

However, other research on Wool wax effectiveness has been lackluster.

A 2014 review of studies concluded that evidence is insufficient that Wool wax relieves nipple pain.
Research in 2017 reported participants were happier with the results of Wool wax cream than with other products, but Wool wax didn't lessen nipple pain or make continued breastfeeding more likely.
A 2021 study said Wool wax wasn't clear whether Wool wax (combined with education about breastfeeding) helped prevent nipple pain.

Wool wax oil is known as an emollient, which means Wool wax helps soothe dry or dehydrated skin.
A 2017 studyTrusted Source indicated that Wool wax can reduce water lost through the skin by 20 to 30 percent.
Simply put, Wool wax is extremely hydrating and has the ability to soften skin to help improve the appearance and the feel of rough, dry, or flaky areas.

Wool wax ’s Cruelty-free:
If you’re ready to clean up your skincare routine, Wool wax is a must.
Wool wax is a by-product of wool washing after shearing, meaning no sheep are harmed in the process.

In fact, if sheep aren’t sheared, their fleece will become solid, too hot and heavy for them so they must be shorn whether we use Wool wax or not.
That’s why our Wool wax is cruelty-free and Leaping Bunny Certified.

Wool wax Provides Dual Benefits:
Wool wax is unique because it is incredibly hydrating without ever feeling sticky.
Wool wax has the dual benefit of being both semi-occlusive and semi-permeable, meaning Wool wax allows your skin to self-hydrate from within while acting as a breathable skin barrier.
These two qualities make Wool wax an incredibly versatile ingredient that is ideal for hydrating dry, flaky skin.

Wool wax Offers The Ultimate In Hydration:
Wool wax can hold up to 400% of its weight in moisture, so you know Wool wax can quench your skin’s thirst.
Another part of the reason why Wool wax is an effective moisturizer is that Wool wax is scientifically proven to mimic lipids in human skin extremely closely.
Your skin will instantly welcome the added hydration!

Wool wax Can Be Used For More Than Cosmetics:
While we love Wool wax for lips and can’t get enough of Wool wax hand cream, this hero ingredient can also be used for more than cosmetics.
Because of Wool wax similarity to the skin’s own oils, doctors often recommend Wool wax to help protect burns and mothers can use Wool wax with nursing infants.

Standards And Legislation About Wool wax:
In addition to general purity requirements, Wool wax must meet official requirements for the permissible levels of pesticide residues.
The Fifth Supplement of the United States Pharmacopoeia XXII published in 1992 was the first to specify limits for 34 named pesticides.

A total limit of 40 ppm (i.e. 40 mg/kg) total pesticides was stipulated for Wool wax of general use, with no individual limit greater than 10 ppm.
A second monograph also introduced into the US Pharmacopoeia XXII in 1992 was entitled 'Modified Wool wax'.

Wool wax conforming to this monograph is intended for use in more exacting applications, for example on open wounds.
In this monograph, the limit of total pesticides was reduced to 3 ppm total pesticides, with no individual limit greater than 1 ppm.

In 2000, the European Pharmacopoeia introduced pesticide residue limits into its Wool wax monograph.
This requirement, which is generally regarded as the new quality standard, extends the list of pesticides to 40 and imposes even lower concentration limits.

Some very high-purity grades of Wool wax surpass monograph requirements.
New products obtained using complex purification techniques produce Wool wax esters in their natural state, removing oxidative and environmental impurities resulting in white, odourless, hypoallergenic Wool wax.

These ultra-high-purity grades of Wool wax are ideally suited to the treatment of dermatological disorders such as eczema and on open wounds.

Wool wax attracted attention owing to a misunderstanding concerning Wool wax sensitising potential.
A study carried out at New York University Hospital in the early 1950s had shown about 1% of patients with dermatological disorders were allergic to the Wool wax being used at that time.

By one estimate, this simple misunderstanding of failing to differentiate between the general healthy population and patients with dermatological disorders exaggerates the sensitising potential of Wool wax by 5,000–6,000 times.

The European Cosmetics Directive, introduced in July 1976, contained a stipulation that cosmetics which contained Wool wax should be labelled to that effect.
This ruling was challenged immediately, and in the early 1980s, it was overturned and removed from the directive.

Despite only being in force for a short period of time, this ruling did harm both to the Wool wax industry and to the reputation of Wool wax in general.
The Cosmetics Directive ruling only applied to the presence of Wool wax in cosmetic products; Wool wax did not apply to the many hundreds of its different uses in dermatological products designed for the treatment of compromised skin conditions.
Modern analytical methods have revealed Wool wax possesses a number of important chemical and physical similarities to human stratum corneum lipids; the lipids which help regulate the rate of water loss across the epidermis and govern the hydration state of the skin.

Cryogenic scanning electron microscopy has shown that Wool wax, like human stratum corneum lipids, consists of a mass of liquid crystalline material.
Cross-polarised light microscopy has shown the multilamellar vesicles formed by Wool wax are identical to those formed by human stratum corneum lipids.

The incorporation of bound water into the stratum corneum involves the formation of multilamellar vesicles.

Skin bioengineering studies have shown the durational effect of the emollient (skin smoothing) action produced by Wool wax is very significant and lasts for many hours.
Wool wax applied to the skin at 2 mg/cm2 has been shown to reduce roughness by about 35% after one hour and 50% after two hours, with the overall effect lasting for considerably more than eight hours.

Wool wax is also known to form semiocclusive (breathable) films on the skin.
When applied daily at around 4 mg/cm2 for five consecutive days, the positive moisturising effects of Wool wax were detectable until 72 hours after final application.

Wool wax may achieve some of its moisturising effects by forming a secondary moisture reservoir within the skin.
The barrier repair properties of Wool wax have been reported to be superior to those produced by both petrolatum and glycerol.

In a small clinical study conducted on volunteer subjects with terribly dry (xerotic) hands, Wool wax was shown to be superior to petrolatum in reducing the signs and symptoms of dryness and scaling, cracks and abrasions, and pain and itch.
In another study, a high purity grade of Wool wax was found to be significantly superior to petrolatum in assisting the healing of superficial wounds.

Manufacturing Methods of Wool wax:
Wool wax is manufacturing by extraction from sheep wool by scouring with dilute alkali, centrifuging, and refining (for the purer grades) via treatment with hot aqueous alkali and then a bleaching agent.

Wool wax is manufacturing by purifying the fatty matter (suint) obtained from the wool of the sheep.
This natural wool fat contains about 30% of free fatty acids and fatty acid esters of cholesterol and other higher alcohols.

The cholesterol compounds are the important constituents, and to secure these in a purified form, many processes have been devised.
In one of these the crude wool fat is treated with weak alkali and the saponified fats and emulsions are centrifuged to secure the aqueous soap solution, from which, on standing, a layer of partially purified wool fat separates.

Wool wax is further purified by treating it with calcium chloride and then dehydrated by fusion with unslaked lime.
Wool wax is finally extracted with acetone, and the solvent subsequently separated by distillation.

Wool wax is obtained by one of the following methods:
1. Solvent extraction of wool fleece.
2. Scouring of wool with soap or neutral detergent followed by:

a. Centrifugation of the resulting emulsion.
This may introduce small amounts of detergents as impurities in the Wool wax.
b. breaking of the emulsion with acid, or production of foam (with air) and collection of the froth.

Handling and storage of Wool wax:

Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Storage class (TRGS 510):
8A: Combustible, corrosive hazardous materials

Stability and reactivity of Wool wax:

Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:

Strong oxidizing agents:

Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:

Waste treatment methods:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.

Contaminated packaging:
Dispose of as unused product

First aid measures of Wool wax:

General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area.

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.

In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.

Rinse mouth with water.
Consult a physician.

Firefighting measures of Wool wax:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.

Accidental release measures of Wool wax:

Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Exposure controls/personal protection of Wool wax:

Control parameters:

Components with workplace control parameters:
Contains no substances with occupational exposure limit values.

Exposure controls:

Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:

Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.

Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested: Dermatril (KCL 740 / Aldrich Z677272, Size M)

Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested: Dermatril (KCL 740 / Aldrich Z677272, Size M)

Wool wax should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.
If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Identifiers of Wool wax:
CAS: 8006-54-0
Deprecated CAS: 8040-96-8, 8038-43-5, 114471-15-7, 8038-41-3
European Community (EC) Number: 232-348-6
UNII: 7EV65EAW6H.
DSSTox Substance ID: DTXSID2027678
NCI Thesaurus Code: C94238
RXCUI: 6227
XANTHAN GUM
Xanthan Gum (/ˈzænθən/) is a polysaccharide with many industrial uses, including as a common food additive.
Xanthan Gum is an effective thickening agent, emulsifier, and stabilizer that prevents ingredients from separating.
Xanthan gum is a polysaccharide with a wide variety of uses, including as a common food additive.


CAS Number:11138-66-2
EC Number: 234-394-2
MDL number: MFCD00131256
Molecular Formula: (C35H49O29)n


Xanthan Gum E code is (E 415).
It’s xanthan gum, a food additive that you’ve probably never heard of but likely consume several times a week.
Moreover, Xanthan Gum’s popularity as a supplement and common ingredient in gluten-free products is growing.


Xanthan Gum may even have health benefits, like lowering cholesterol and blood sugar levels.
Xanthan Gum’s created when sugar is fermented by a type of bacteria called Xanthomonas campestris.
When sugar is fermented, Xanthan Gum creates a broth or goo-like substance, which is made solid by adding an alcohol.


Xanthan Gum is then dried and turned into a powder.
When xanthan gum powder is added to a liquid, Xanthan Gum quickly disperses and creates a viscous and stable solution.
This makes it a great thickening, suspending and stabilizing agent for many products.


Xanthan Gum was discovered by scientists in 1963.
Since then, Xanthan Gum has been well researched and determined safe.
Therefore, the FDA has approved as a food additive and placed no limitations on the amount of xanthan gum a food can contain.


Even though it’s made in a lab, Xanthan Gum’s a soluble fiber.
Xanthan Gum is soluble fibers are carbs that your body cannot breakdown.
Instead, they absorb water and turn into a gel-like substance in your digestive system, which slows digestion.


Therefore, your body is unable to digest xanthan gum, and it does not provide any calories or nutrients.
Xanthan Gum is obtained from the fermentation of various sugar species with the bacteria Xanthomonas campestris.
Xanthan Gum's physical structure is powder.


Xanthan Gum is among the food additives with the code E415.
Xanthan Gum can be produced from simple sugars using a fermentation process and derives its name from the species of bacteria used, Xanthomonas campestris.
Xanthan gum, 1%, can produce a significant increase in the viscosity of a liquid.


Xanthan Gum can be produced from a range of simple sugars using a fermentation process, and derives its name from the strain of bacteria used in this: Xanthomonas campestris.
Xanthan gum, a microbial heteropolysaccharide, basically consists of a main polymer skeleton with 1,4-linked β-D-glucose units as in cellulose.


In the side chains attached to this skeleton, there is a trisaccharide consisting of a D-glucorinic acid residue between two D-mannose residues.
The polymer also contains 4.7% of O-acetyl groups and 3.0-3.5% of pyruvic acid, which is a ketal in the glucose unit.
These side chains, which are found in xanthan gum and make up about 60% of the molecule, can impart many physical and chemical properties specific to xanthan gamma.


Due to its side chains, xanthan gum can be fully hydrated even in the cold chain.
It is further stated that these side chains make the xanthan gum resistant to hydrolysis.
Xanthan gum is ground to powder and packaged after sifting.


Xanthan Gum contains D-gluco and D-mannose as the predominant hexose, and D-glucuronic acid and pyruvic acid and is prepared as sodium, potassium or calcium salts and its solutions are neutral.
Xanthan Gum is made by fermenting simple sugars with a specific strain of bacteria called Xanthomonas campestris.


Xanthan Gum is a white or off-white powder that is soluble in both hot and cold water.
Xanthan Gum was first discovered in the early 1960s by researchers at the United States Department of Agriculture (USDA) who were studying a strain of bacteria called Xanthomonas campestris.


This strain of bacteria is commonly found in soil and on plant surfaces, and can cause a variety of plant diseases.
The researchers found that when they grew the Xanthomonas campestris bacteria in a culture medium containing simple sugars like glucose or sucrose, the bacteria produced a slimy substance that could thicken and stabilize liquids.


They later identified this substance as xanthan gum.
Xanthan gum, also known as E415, is a natural polysaccharide with a high molecular weight containing mainly glucose, mannose and glucuronic acid.
Xanthan gum produced by microbial fermentation using Xanthomonas campestris bacteria has a wide range of uses in the food, pharmaceutical, cosmetics and textile industries.


Commercial xanthan gum in the form of yellowish powder gives high viscosity to the solution it is added to, even at low concentrations.
Xanthan gum is a polysaccharide with a wide variety of uses, including as a common food additive.
Xanthan gum is a natural biopolymer produced by the bacteria Xanthomonas campestris by fermentation of sugar, dextrose, corn syrup or starch.


E code of Xanthan Gum is E415 .
Xanthan Gum is soluble in both hot and cold water.
The main advantages of using xanthan gum are that it provides high-viscosity solutions at low concentrations, is stable at a wide range of pH levels and temperatures, and is compatible with salt and enzyme-containing applications.


Xanthan Gum is a food thickening agent made from bacteria with the ability to infect a large number of plants.
Xanthan Gum can improve the structure, consistency, flavor and shelf life of many foodstuffs.
It is xanthan gum that stabilizes food and helps it withstand different temperatures and pH levels.


Xanthan Gum prevents the food from separating and ensures that it flows smoothly from the containers it is in.
Xanthan Gum is a popular food additive added as a thickener (bulking) or stabilizer in foods.
Xanthan Gum has high viscosity even in low polymer structures.


Xanthan Gum has high viscosity resists flow.
Gum solutions are pseudoplastic or shear thinning, and their viscosity decreases with increasing shear rate.
Xanthan Gum's viscosity is dependent on temperature (both dissolution and measurement temperatures), biopolymer concentration, salt concentration and pH.


Xanthan Gum has the best stabilization between pH 4 and pH 10.
Xanthan Gum's solution with 1% concentration provides a viscosity of 1000 centipoise.
Xanthan Gum's density at 20 °C is 1.50 gr/cm³.


Xanthan gum, which is widely used in food applications, is a heteropolysaccharide produced by immersion aerobic fermentation using a bacterium called Xanthomonas campestris, and carbohydrate, a suitable nitrogen source, potassium phosphate and other trace elements constitute the sterile fermentation medium.
The polysaccharide produced at the end of the fermentation stage is precipitated by using isopropyl alcohol and isolated from the environment.


The isolated polysaccharide is then centrifuged to remove residual isopropyl alcohol and subsequently dried.
The dried Xanthan gum is ground to powder and packaged after sifting.
Xanthan Gum contains D-gluco and D-mannose as the predominant hexose, and D-glucuronic acid and pyruvic acid and is prepared as sodium, potassium or calcium salts and its solutions are neutral.


Xanthan Gum consists of a main polymer backbone with D-glucose units.
In the side chains attached to this skeleton, there is a trisaccharide consisting of a D-glucorinic acid residue between two D-mannose residues.
The polymer also contains 4.7% of O-acetyl groups and 3.0-3.5% of pyruvic acid, which is a ketal in the glucose unit.


These side chains, which are found in xanthan gum and make up about 60% of the molecule, can impart many physical and chemical properties specific to xanthan gamma.
Due to its side chains, xanthan gum can be fully hydrated even in the cold chain.
It is further stated that these side chains make the xanthan gum resistant to hydrolysis.


Xanthan Gum is soluble in water but insoluble in organic solvents; It is used as a rheological control agent in systems containing water and as a stabilizer for emulsions and suspensions.
Apart from these, xanthan gam; It retains water, increases freeze-thaw stability, prevents retrogradation of starch and improves shelf life.


These properties of xanthan gum, which can be easily dissolved in 8% solutions of sulfuric, nitric and acetic acids, 10% of hydrochloric acid and 25% of phosphoric acid, can maintain its durability for months as long as the temperature does not rise.
Commercial xanthan gum is a yellowish powdery substance that dissolves completely in hot or cold water, yielding high viscosity solutions at low concentrations.


Aqueous solutions of Xanthan gum can tolerate some hydrophilic solutions such as ethanol and propylene glycol up to a concentration of up to 50%.
The viscosity of Xanthan gum is a function of the concentration in its distribution.
As with other gums, xanthan gum solutions exhibit a pseudoplastic fluid type.


Pseudoplastic fluid type feature; It also contributes significantly to the formation of properties that affect many sensory qualities such as mouthfeel, perception of taste and suspension formation.
Another distinctive feature of Xanthan gum that distinguishes it from other gums is that it is highly resistant to temperature and pH.


It has been stated that this durability is due to the side chains in the xanthan molecule wrapping around the cellulose skeleton.
This feature is the xanthan gamut; It makes it resistant to degradation that may occur as a result of enzymes, acids, bases, high temperatures, freezing and thawing and prolonged mixing.


The interaction of these trisaccharide chains with the main chain turns the molecule into a highly rigid rod and tremendously increases its heat, acid and base stability.
Its molecular weight is around 2 million, and larger values ​​are reported, probably due to aggregation.
The xanthans with the highest pyruvic acid content have the highest viscosity and thermal stability.


Xanthan gum solutions;
It is generally unaffected by changes in pH and dissolves in most acids and bases.
Most other hydrocolloids;
While it loses its viscosity at low pH values ​​and high temperatures, xanthan gum remains stable under the same conditions.



USES and APPLICATIONS of XANTHAN GUM:
Xanthan gum is used in many industrial products due to its ability to withstand different temperatures and pH levels, cling to surfaces and thicken liquids, all while maintaining good flow.
In foods, xanthan gum is common in salad dressings and sauces.


Xanthan Gum helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier.
Xanthan gum also helps suspend solid particles, such as spices.
Xanthan gum helps create the desired texture in many ice creams.


Toothpaste often contains xanthan gum as a binder to keep the product uniform.
Xanthan gum also helps thicken commercial egg substitutes made from egg whites, to replace the fat and emulsifiers found in yolks.
Xanthan Gum is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages at typical use levels.


In gluten-free baking, xanthan gum is used to give the dough or batter the stickiness that would otherwise be achieved with gluten.
In most foods Xanthan Gum is used at concentrations of 0.5% or less.
Xanthan gum is used in a wide range of food products, such as sauces, dressings, meat and poultry products, bakery products, confectionery products, beverages, dairy products, and others.


In the oil industry, xanthan gum is used in large quantities to thicken drilling mud.
These fluids carry the solids cut by the drilling bit to the surface. Xanthan gum provides great "low end" rheology.
When circulation stops, the solids remain suspended in the drilling fluid.


The widespread use of horizontal drilling and the demand for good control of drilled solids has led to its expanded use.
Xanthan Gum has been added to concrete poured underwater, to increase its viscosity and prevent washout.
In cosmetics, xanthan gum is used to prepare water gels.


Xanthan Gum is also used in oil-in-water emulsions to enhance droplet coalescence.
Xanthan gum is under preliminary research for its potential uses in tissue engineering to construct hydrogels and scaffolds supporting three-dimensional tissue formation.
Furthermore, thiolated xanthan gum has shown potential for drug delivery, since by the covalent attachment of thiol groups to this polysaccharide high mucoadhesive and permeation enhancing properties can be introduced.


Whey-derived xanthan gum is commonly used in many commercial products, such as shampoos and salad dressings.
Xanthan Gum is a powerful thickening agent, and also has uses as a stabilizer to prevent ingredients from separating.
Xanthan gum is a popular food additive that’s commonly added to foods as a thickener or stabilizer.


Xanthan Gum is most often used as a food ingredient as an effective thickening agent and stabilizer to prevent ingredients from separating.
Xanthan Gum is also used for those properties in other industries, such as oil, cosmetics.
Xanthan Gum is generally used as a thickener (such as Guar Gum E412, Gum Arabic E414, Carboxymethyl Cellulose CMC E466, Pectin E440, Sodium Alginate E401) and stabilizer.


Xanthan Gum is soluble in water but insoluble in organic solvents.
Xanthan Gum is used as a rheological control agent in systems containing water and as a stabilizer for emulsions and suspensions.
Apart from these, xanthan gam; It retains water, increases freeze-thaw stability, prevents retrogradation of starch and improves shelf life.


Xanthan gum, which is widely used in food applications, is a heteropolysaccharide produced by immersion aerobic fermentation using a bacterium called Xanthomonas campestris, and carbohydrate, a suitable nitrogen source, potassium phosphate and other trace elements constitute the sterile fermentation medium.
The polysaccharide produced at the end of the fermentation stage is precipitated by using isopropyl alcohol and isolated from the environment.


The isolated polysaccharide is then centrifuged to remove residual isopropyl alcohol and subsequently dried.
Xanthan Gum is a type of polysaccharide, or carbohydrate, that is commonly used as a food additive to thicken, stabilize, and improve the texture of foods.
Xanthan gum is often used in gluten-free baking as a substitute for gluten, as it can help mimic the texture and structure of gluten in baked goods.


Xanthan Gum is also commonly found in salad dressings, sauces, ice cream, and other processed foods to improve their texture and prevent them from separating or breaking down.
Additionally, Xanthan Gum can be used in industrial applications such as oil drilling and cosmetics due to its thickening and stabilizing properties.


Xanthan gum is generally considered safe for consumption and is approved for use as a food additive by many regulatory agencies around the world.
Xanthan gum has a wide range of applications in food, beverage, and other industries.
Xanthan gum is used synergistically with carob gum and tara gum to form thermo-reversible gels, and when used in combination with guar gum, it provides higher viscosity.


Xanthan gum is used in many applications to provide excellent suspension, emulsion stability, viscosity, moisture retention and freeze-thaw stability.
Xanthan Gum is a powerful thickening agent, and also has uses as a stabilizer to prevent ingredients from separating.
Apart from the food industry, where Xanthan Gum is widely used as an additive, it is included in the formulation as a thickener and stabilizer in the production of various products from textiles to cleaning agents, from pharmaceuticals and cosmetics to paints and inks.


Xanthan Gum is used as a thickening agent and stabilizer in a variety of foods.
Also prevents ice crystals from forming in ice creams and provides a "fat feel" in low or no-fat dairy products.
For best results, use 1/2 teaspoon xanthan gum per cup of liquid called for in recipe.
Whip in a blender with liquid to prevent clumping.


Xanthan Gum also promotes a good rise in gluten-free baked goods. Add 1 teaspoon xanthan gum per cup of gluten-free flour in yeast bread or pizza recipes.
1/2 teaspoon per cup in cake or muffin recipes.
Blend with dry ingredients to prevent clumping.


Since the solution viscosity does not change much with temperature, that is, the consistency does not increase when cooled, xanthan gum is very suitable for use in products such as salad dressings and chocolate syrups that will be consumed as soon as they come out of the refrigerator.
These products should be able to pour as easily as at room temperature as soon as they come out of the refrigerator.


In normal salad dressings, xanthan gum is used as a thickener and the particles stabilize the suspension in the structure and the emulsion of oil in water.
Xanthan gum is generally used with alginate in propylene glycol structure.
When used together, they give less pseudoplastic and less viscous solution.


The resulting product has better pourability and a cream-like smooth texture.
Xanthan gum; compatible with other hydrocolloids; especially locust bean gum and Konjacla (gel formation) and Guar gum (high viscosity) show synergistic effects.
Xanthan gum and guar gum / carob gum combinations are used in the stabilization of ice cream and frozen products.


The addition of carrageenan to this mixture prevents the separation of the liquid phase during freezing.
Double or triple combinations of these gums are used in various dairy products.
Finally, Xanthan Gum is used in toothpaste, cosmetics, cleaning products, coatings and paints and fire extinguishers in technical fields.


Xanthan Gum provides emulsification in salad dressings.
Xanthan gum is used in the manufacture of salad dressings to ensure that the dressings penetrate the salads well.
Xanthan gum is used as a thickener and emulsifier, as a binder, instead of gluten in bakery products.


Xanthan Gum is used as a thickening agent in mosquito repellent sprays.
Xanthan Gum is used in fruit drinks, helping the suspended beverage to have a better appearance.
Xanthan Gum is a substance with rapid solubility in low pH environments.


In this way, Xanthan Gum suspends other insoluble particles.
Xanthan Gum is used in the production of instant soup.
In frozen dairy products, xanthan gum used together with methyl cellulose and carboxymethylcellulose has very good effects.


In the manufacture of cheeses, Xanthan Gum provides hardness with a mixture of guar gum and carob gum.
In addition, Xanthan Gum provides flavor release in flat cheeses.
Due to its high resting viscosity, Xanthan Gum is used as a food additive because it gives very good consistency and flow properties in the manufacture of syrups .


Xanthan Gum is used as a thickening agent in powder disinfectants produced for disinfection of the nipples of dairy animals.
At the same time , Silicon Dioxide or Tricalcium Phosphate is used as anti-caking agent .
Xanthan Gum is used in the manufacture of low-fat foods.


Xanthan Gum is possible to produce water-dispersible stabilizers with some surfactants and substances such as lecithin.
For this, Xanthan gum is the main ingredient.
Xanthan gum is used as a thickening agent in the manufacture of many personal care and beauty products.


Xanthan Gum is used to stabilize suspensions and emulsions in the food industry, where it is used as a thickener.
Xanthan Gum is used in the manufacture of toothpaste, creams, lotions and shampoos.
Xanthan Gum is used in these application areas for its viscosity increasing feature and to provide a good flow feature.


In the production of toothpaste, Xanthan Gum ensures that the products keep their shape and that the emulsifier feature works in the best way.
Xanthan Gum is also used as a thickener in the production of toothpaste.
In this application, Xanthan Gum is used together with glycerin , maltodextrin , activated carbon , zinc lactate, benzyl alcohol, sodium benzoate , sodium bicarbonate and potassium sorbate .


Due to its ability to withstand different temperatures and pH levels in many industrial products, Xanthan Gum adheres to surfaces and provides excellent fluidity by thickening liquids.
Xanthan gum is used as a thickening agent in the manufacture of fungicides, herbicides and insecticides.


Xanthan Gum is used in the manufacture of tile, mortar and toilet bowl cleaning chemicals.
Xanthan Gum is a thickening agent used in creams produced for acne treatment.
Xanthan Gum is used in manufacturing formulations of some paints.


Xanthan Gum helps the skin to retain moisture in cosmetic creams produced for wrinkle filling.
Xanthan Gum acts as a stabilizer in the production of cosmetic creams, which are produced to increase the production of hyaluronic acid.
In pharmaceutical preparations, Xanthan Gum is used together with Salicylic Acid and some other chemicals for the treatment of acne and acne, providing consistency and binding of other substances of the drug.


In the manufacture of adhesives such as wallpaper glues, xanthan gum is an important ingredient to thicken.
In oil fields, Xanthan Gum is used together with oxidizing agents such as sodium percarbonate and ammonium persulfate to form a cracking agent.
Xanthan Gum is used as a binder in the production of tablets used as a controlled release agent in wine production.


In this way, Xanthan Gum helps to keep the other excipients and active substance used together.
Xanthan Gum is used as a thickener in the production of auto shampoo.
Xanthan Gum is a stabilizer used in skin lightening compositions.


Xanthan Gum has thickening properties in the production of shampoo used to wash the hair of horses.
Hair application components have recently taken an important place in the field of cosmetics.
The most important factors affecting the preferability of these cosmetic products are the ease of application and the minimum level of skin irritation.


For this, Xanthan Gum is processed by using it with other thickening agents.
Xanthan Gum is used as a stabilizer and thickener additive in food production.
Xanthan Gum gives high consistency even at very low concentration.


In many food products, 0.05% - 0.5% Xanthan Gum is used.
Xanthan gum is a chain of sugar building blocks made by fermenting simple sugars with a specific kind of bacteria.
Xanthan Gum is sometimes used to make medicine.


Xanthan gum is used for diabetes, constipation, dry eye, and many other conditions, but there is no good scientific evidence to support most of these uses.
In manufacturing, xanthan gum is used as a thickening and stabilizing agent in foods, toothpastes, and medicines.


-Oil and gas: Xanthan gum is used in the oil and gas industry as a drilling fluid additive to increase viscosity and suspend solids.
-Industrial: Xanthan gum is also used in a variety of industrial applications, including in adhesives, coatings, and textile printing.
Xanthan gum is a useful ingredient in many food products, cosmetics, and other industrial applications due to its unique combination of properties.


-Food:
Xanthan gum is often used as a thickener, stabilizer, and emulsifier in a variety of food products, including sauces, dressings, soups, and baked goods.
-Pharmaceutical:
Xanthan gum is used in the pharmaceutical industry as a binder, stabilizer, and disintegrant in tablet formulations.


-Beverage:
Xanthan gum can be used to stabilize beverages, prevent sedimentation, and improve mouthfeel.
Xanthan Gum is often used in fruit juices, dairy products, and alcoholic beverages.


-Personal care products:
Xanthan gum is a common ingredient in personal care products, such as toothpaste, shampoo, and lotion.
Xanthan Gum is used to improve texture and provide a smooth, even consistency.


-Usage areas of Xanthan Gum:
• Forming Visible Clear Solutions Even at High Concentrations,
• Dissolving in Both Hot and Cold Water,
• Giving High Viscosity to Solutions Even at Low Polysaccharide Concentrations,
• Minimal Change in Viscosity of Solutions Formed by Xanthan at Wide Temperature Ranges,
• Both in Acidic and Alkaline Solutions Dissolution and Stability,
• Remaining Stable in Solutions with High Salt Concentration,
• High Resistance to Enzymatic Degradation,
• Being a Good Lubricant,
• Providing Stability After Freezing/Thawing Stages,
• Being an Extremely Effective Emulsion Stabilizer,
• Providing Excellent Mouth Taste ,
• Showing Synergistic Properties with Other Hydrocolloids (Guar and Locust Bean Gumla)
• Tomato Paste and Salad Dressings,
• Bakery and Pastry Products,
• Meat Products,
• Beverages,
• Fruit Preparations,
• Powder Products.


-As food application areas;
• tomato paste and salad dressings,
• bakery and pastry products,
• meat products,
• beverages,
• fruit preparations,
• powder products.


-The following are some common products that contain xanthan gum:
*Toothpaste
*Creams
*Lotions
*Shampoo
*Industrial Products


-Common industrial products containing xanthan gum include:
*Fungicides, herbicides and insecticides
*Tile, grout, oven and toilet bowl cleaners
*Paints
*Fluids used in oil drilling
*Adhesives like wallpaper glue



XANTHAN GUM FEATURES AND BENEFITS:
• forming visibly clear solutions even at high concentrations,
• dissolving in both hot and cold water,
• imparting high viscosity to solutions even at low polysaccharide concentrations,
• minimal change in the viscosity of solutions formed by xanthan at wide temperature ranges,
• soluble and stable in both acidic and alkaline solutions,
• high salt concentration to remain stable in solutions,
• to show high resistance to enzymatic degradation,
• to be a good lubricant,
• to provide stability after freezing/thawing stages,
• to be an extremely effective emulsion stabilizer,
• to give an excellent mouthfeel,
• It can be counted as showing synergistic properties with other hydrocolloids (guar and locust bean gum).



FUNCTIONS AND APPLICATIONS OF XANTHAN GUM:
1. Xanthan Gum helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier.
2. Xanthan gum also helps suspend solid particles, such as spices.
3. Xanthan gum helps create the pleasant texture in many ice creams, along with guar gum and locust bean gum.
4. Xanthan gum is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages



FUNCTIONS OF XANTHAN GUM:
Xanthan gum is a versatile ingredient that has several functions in food and other industries. Its primary function is as a thickener and stabilizer, but it also has other properties, including:

*Thickening: Xanthan gum can thicken liquids at low concentrations and create a smooth, uniform texture in food products.
*Stabilizing: Xanthan gum can help stabilize emulsions, preventing the separation of oil and water in food products.

*Suspending: Xanthan gum can suspend particles in liquid, preventing them from settling to the bottom of a product.
*Binding: Xanthan gum can bind ingredients together, improving the texture and quality of baked goods and other food products.

*Improving mouthfeel: Xanthan gum can improve the mouthfeel of products, creating a smooth, creamy texture.
*Increasing shelf life: Xanthan gum can help extend the shelf life of food products by preventing moisture loss and controlling crystallization.



FUNCTIONS AND APPLICATIONS OF XANTHAN GUM:
1. Xanthan Gum helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier.
2. Xanthan gum also helps suspend solid particles, such as spices.
3. Xanthan gum helps create the pleasant texture in many ice creams, along with guar gum and locust bean gum.
4. Xanthan gum is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages



WHAT ARE XANTHAN GUM'S PHYSICAL AND CHEMICAL PROPERTIES?
Among its most distinctive features is its solubility in both cold and hot water.
The feature here is due to the polyelectrolyte properties of Xanthan Gum.
Xanthan Gum is insoluble in organic solvents.
Xanthan Gum can be added up to 50% level into Isopropyl Alcohol, Methyl Alcohol , Ethyl Alcohol and Acetone.



WHERE IS XANTHAN GUM FOUND?
Xanthan gum is found in food, personal care and industrial products.
-Food Products:
Xanthan gum can improve the texture, consistency, flavor, shelf life and appearance of many foods.
Xanthan Gum also stabilizes foods, helping certain foods withstand different temperatures and pH levels.
Additionally, Xanthan Gum prevents foods from separating and allows them to flow smoothly out of their containers.
Xanthan Gum’s used frequently in gluten-free cooking since it can provide the elasticity and fluffiness that gluten gives traditional baked goods.

The following are some common foods that contain xanthan gum:
*Salad dressings
*Bakery products
*Fruit juices
*Soups
*Ice creams
*Sauces and gravies
*Syrups
*Gluten-free products
*Low-fat foods
*Personal Care Products

Xanthan gum is also found in many personal care and beauty products.
Xanthan Gum allows these products to be thick, but still flow easily out of their containers.
Xanthan Gum also allows solid particles to be suspended in liquids.



SHEAR THINNING OF XANTHAN GUM:
The viscosity of xanthan gum solutions decreases with higher shear rates.
This is called shear thinning or pseudoplasticity.
This means that a product subjected to shear, whether from mixing, shaking or chewing will thin.
When the shear forces are removed, the food will thicken again.
In salad dressing, the addition of xanthan gum makes it thick enough at rest in the bottle to keep the mixture fairly homogeneous, but the shear forces generated by shaking and pouring thins it, so it can be easily poured.
When it exits the bottle, the shear forces are removed and Xanthan Gum thickens again, so it clings to the salad.



AMOUNTS USED OF XANTHAN GUM:
The greater the ratio of xanthan gum added to a liquid, the thicker the liquid will become.
An emulsion can be formed with as little as 0.1% (by weight).
Increasing the amount of gum gives a thicker, more stable emulsion up to 1% xanthan gum.
A teaspoon of xanthan gum weighs about 2.5 grams and brings one cup (250 ml) of water to a 1% concentration.
To make a foam, 0.2–0.8% xanthan gum is typically used.
Larger amounts result in larger bubbles and denser foam.
Egg white powder (0.2–2.0%) with 0.1–0.4% xanthan gum yields bubbles similar to soap bubbles.



HOW IS XANTHAN GUM PRODUCED?
Xanthan Gum production occurs when the sugar is fermented by a type of bacteria called Xanthomonas campestris.
In the production process here, when sugar is fermented, a broth-like substance is formed and after the drying phase it is pulverized.
Xanthan Gum powder disperses quickly when added to a liquid, forming a viscous, yet stable solution.

This feature adds thickening, suspending and stabilizing agent properties for many products.
To produce Xanthan Gum, X Campestris needs a variety of nutrients, including micronutrients (Examples; Potassium, Iron and Calcium Salts) and macronutrients such as carbon and Nitrogen.
Glucose and sucrose are the most commonly used carbon sources in the production of this chemical.

In the production of Xanthan Gum (Xanthan Gum), the concentration of the carbon source affects the yield in the reaction.
In the production of Xanthan Gum (Xanthan Gum), 2%-4% concentration is preferred.
Substrate concentrations above this inhibit growth.
Nitrogen, an essential nutrient, is supplied either as an organic compound or as an inorganic molecule.



COMMERCIAL XANTHAN GUM PRODUCTION:
The commercial production of xanthan gum involves fermenting a sugar source with the Xanthomonas campestris bacteria in large-scale fermentation tanks.
The steps involved in the production process are as follows:
*Inoculation:
The Xanthomonas campestris bacteria are first grown in a small culture and then transferred to a larger fermenter vessel.

*Fermentation:
The bacteria are grown in a liquid medium containing a sugar source such as glucose, sucrose, or lactose.
The fermentation process takes place under controlled conditions of temperature, pH, and oxygen level.

*Separation:
Once the fermentation is complete, the gellan gum is separated from the bacterial biomass and the fermentation medium.
This is typically done using a series of filtration and centrifugation steps.

*Purification:
Once the fermentation is complete, the mixture is heated to stop the growth of bacteria, and the xanthan gum is extracted from the liquid by precipitation with alcohol or isopropanol.
The xanthan gum is then washed and dried to create a fine powder.

*Milling and Packaging:
The dried xanthan gum is milled into a fine powder and packaged into bags or drums for distribution.
The quality of the xanthan gum depends on factors such as the type of sugar source used, the fermentation conditions, and the purification process.
The resulting xanthan gum powder is used as a food additive in a variety of applications, such as thickening, stabilizing, and emulsifying.



PREPARATION OF XANTHAN GUM:
Xanthan gum is produced by the fermentation of glucose and sucrose.
The medium is well-aerated and stirred, and the xanthan polymer is produced extracellularly into the medium.
After one to four days, the polymer is precipitated from the medium by the addition of isopropyl alcohol, and the precipitate is dried and milled to give a powder that is readily soluble in water or brine.
Xanthan Gum is composed of pentasaccharide repeat units, comprising glucose, mannose, and glucuronic acid in the molar ratio 2:2:1.
A strain of X. campestris has been developed that will grow on lactose - which allows it to be used to process whey, a waste product of cheese production.
This can produce 30 g/L of xanthan gum for every 40 g/L of whey powder.



OTHER HEALTH BENEFITS OF XANTHAN GUM:
Xanthan gum has been linked to other potential health benefits, though these benefits are unlikely to occur without taking supplements.
Some potential health benefits of xanthan gum include:
*Lower cholesterol:
A study had five men consume 10 times the recommended amount of xanthan gum per day for 23 days.
Subsequent blood tests found that their cholesterol decreased by 10%.

*Weight loss:
People have noted increased fullness after consuming xanthan gum.
Xanthan Gum may increase fullness by delaying stomach emptying and slowing digestion.

*Improved regularity:
Xanthan gum increases the movement of water into the intestines to create a softer, bulkier stool that’s easier to pass.
Studies have found that it significantly increases the frequency and amount of stool.

*Thickens liquids:
Xanthan Gum is used to thicken liquids for those who have difficulty swallowing, such as older adults or people with neurological disorders.
*Saliva substitute:
Xanthan Gum is sometimes used as a saliva substitute for individuals suffering from dry mouth, but studies on its effectiveness have found mixed results.



HOW DOES XANTHAN GUM WORK?
Xanthan gum swells in the intestine, which stimulates the intestine to push stool through.
Xanthan Gum also seems to slow the absorption of sugar from the digestive tract.



XANTHAN GUM MAY LOWER BLOOD SUGAR:
Several studies have found that xanthan gum can lower blood sugar when consumed in large doses.
Xanthan Gum’s believed that it turns fluids in your stomach and small intestine into a viscous, gel-like substance.
This slows digestion and affects how quickly sugar enters your bloodstream, decreasing blood sugar spikes after eating.

One 12-week study had nine men with diabetes and four without diabetes eat a daily muffin.
For six weeks of the study, the men ate muffins without xanthan gum.
For the other 6 weeks, they ate muffins containing 12 grams of it.

The participants’ blood sugars were tested regularly, and both fasting and after-meal blood sugar levels in the men with diabetes were significantly lower when consuming the muffins with xanthan gum.
Another study in 11 women found that blood sugars were significantly lower after consuming rice with added xanthan gum, compared to consuming rice without it.



HISTORY OF XANTHAN GUM:
Xanthan gum was discovered by Allene Rosalind Jeanes and her research team at the United States Department of Agriculture, and brought into commercial production by CP Kelco under the trade name Kelzan in the early 1960s.
Xanthan Gum was approved for use in foods in 1968 and is accepted as a safe food additive in the USA, Canada, European countries, and many other countries, with E number E415, and CAS number 11138-66-2.
Xanthan gum derives its name from the species of bacteria used during the fermentation process, Xanthomonas campestris.



DETAIL OF THE BIOSYNTHESIS OF XANTHAN GUM:
Synthesis originates from glucose as substrate for synthesis of the sugar nucleotides precursors UDP-glucose, UDP-glucuronate, and GDP-mannose that are required for building the pentasaccharide repeat unit.
This links the synthesis of xanthan to carbohydrate metabolism.

The repeat units are built up at undecaprenylphosphate lipid carriers that are anchored in the cytoplasmic membrane.
Specific glycosyltransferases sequentially transfer the sugar moieties of the nucleotide sugar xanthan precursors to the lipid carriers.
Acetyl and pyruvyl residues are added as non-carbohydrate decorations.
Mature repeat units are polymerized and exported in a way resembling the Wzy-dependent polysaccharide synthesis mechanism of Enterobacteriaceae.
Products of the gum gene cluster drive synthesis, polymerization, and export of the repeat unit.



PHYSICAL and CHEMICAL PROPERTIES of XANTHAN GUM:
Form: Powder
Appearance: white or cream-color and free-flowing powder
Viscosity: 1200 - 1600 mpa.s
Assay(on dry basis): 91.0 - 108.0%
Loss on drying(105o­C, 2hr): 6.0 - 12.0%
V1 : V2: 1.02 - 1.45
Pyruvic Acid: ≥ 1.5%
PH of 1% solution in water: 6.0 - 8.0
Heavy metals(as Pb): ≤ 20 mg/kg
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available

Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available



FIRST AID MEASURES of XANTHAN GUM:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of XANTHAN GUM:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of XANTHAN GUM:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of XANTHAN GUM:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of XANTHAN GUM:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.
hygroscopic
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of XANTHAN GUM:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
Gum xanthan


XANTHAN GUM
DESCRIPTION:
Xanthan gum is a polysaccharide with many industrial uses, including as a common food additive.
Xanthan gum is an effective thickening agent, emulsifier, and stabilizer that prevents ingredients from separating.
Xanthan gum can be produced from simple sugars using a fermentation process and derives its name from the species of bacteria used, Xanthomonas campestris.

CAS number 11138-66-2
EC Number: 234-394-2

Xanthan gum is a popular food additive that’s commonly added to foods as a thickener or stabilizer.
Xanthan gum is created when sugar is fermented by a type of bacteria called Xanthomonas campestris.
When sugar is fermented, Xanthan gum creates a broth or goo-like substance, which is made solid by adding an alcohol.
Xanthan gum is then dried and turned into a powder.

When xanthan gum powder is added to a liquid, Xanthan gum quickly disperses and creates a viscous and stable solution.
This makes Xanthan gum a great thickening, suspending and stabilizing agent for many products.

Xanthan gum was discovered by scientists in 1963.
Since then, Xanthan gum has been well researched and determined safe.
Therefore, the FDA has approved Xanthan gum as a food additive and placed no limitations on the amount of xanthan gum a food can contain.

Even though Xanthan gum is made in a lab, Xanthan gum is a soluble fiber.
Soluble fibers are carbs that your body cannot breakdown.

Instead, they absorb water and turn into a gel-like substance in your digestive system, which slows digestion

Xanthan gum is a chain of sugar building blocks made by fermenting simple sugars with a specific kind of bacteria.
Xanthan gum is sometimes used to make medicine.
Xanthan gum is used for diabetes, constipation, dry eye, and many other conditions, but there is no good scientific evidence to support most of these uses.
In manufacturing, xanthan gum is used as a thickening and stabilizing agent in foods, toothpastes, and medicines.

Xanthan gum is a substance used in making some foods and medications.
Xanthan gum has different effects in these products: Xanthan gum can add thickness, keep textures from changing, and hold ingredients in place.

Xanthan gum is found in many types of medicines. These include:
• Tablets that slowly break down in the body
• Liquid drops for the eyes
Xanthan gum is produced by fermenting a carbohydrate (a substance that contains sugar) with Xanthomonas campestris bacteria, then processing it.

An additive used as a thickener, stabiliser and emulsifier, xanthan gum is made when strains of the Xanthomonas campestris bacteria are fed a solution of glucose that's been derived from corn, soy, dairy or wheat.
The bacteria ferments the sugary solution, and as a result develops a sticky protective coat that has a consistency that makes Xanthan gum suitable for binding and thickening.
It's these properties that make xanthan gum useful in food production – most notably in gluten-free baking, where Xanthan gum helps starches combine and improves the texture, rise and shelf-life of gluten-free bakes.

Xanthan gum is also used in numerous household products, from wallpaper paste to cosmetics.
Xanthan Gum is a plant-based thickening and stabilizing agent and food additive.
Xanthan gum is named for the bacteria, Xanthomonas campestris, which plays a crucial role in this description.
Technically speaking, xanthan gum is a polysaccharide, which is just a fancy way to say "a string of multiple sugars."

To create xanthan gum, the Xanthomonas campestris bacterium is allowed to ferment on a sugar.
The result is a gel that is then dried and milled to create the powder substance.
Xanthan gum has a number of powerful properties as a food additive.

First, Xanthan gum works as an emulsifier, encouraging liquids that normally don't like one another to mix together.
Second, Xanthan gum works as thickener, increasing the viscosity of liquids and batters.
Third, Xanthan gum can create a creamy texture in items like ice cream and salad dressings.

In the world of gluten-free baking, xanthan gum plays the crucial role of imitating gluten.
In baking, gluten is what makes dough "doughy."
Xanthan gum gives the dough elasticity, as well as viscosity.

Those properties help to hold a cookie together while it bakes on a sheet in the oven, and they enable cakes and breads to hold onto the gas bubbles that form inside them.
This allows them to rise and take shape.
Xanthan gum helps replicate these properties in recipes that do not contain gluten, like delicious cinnamon rolls that are gluten free.


PRODUCTION OF XANTHAN GUM:
Xanthan gum is derived naturally from X. campestris, which is a plant pathogen, being responsible for diseases such as black rot in brassica crops (e.g., cauliflower and cabbage).
The gum is produced when sugar, commonly from corn, wheat, or soy, is fermented by X. campestris.
The gum is then processed, through pasteurization, drying, and milling, to create a fine white powder or, occasionally, granules.
The final product, a kind of hydrocolloid, disperses and creates a gel when added to water.


HISTORY OF XANTHAN GUM:
Xanthan gum was discovered by Allene Rosalind Jeanes and her research team at the United States Department of Agriculture, and brought into commercial production by CP Kelco under the trade name Kelzan in the early 1960s.
Xanthan gum was approved for use in foods in 1968 and is accepted as a safe food additive in the US, Canada, European countries, and many other countries, with E number E415, and CAS number 11138-66-2.

Xanthan gum derives its name from the species of bacteria used during the fermentation process, Xanthomonas campestris.

USES OF XANTHAN GUM:
Xanthan gum, 1%, can produce a significant increase in the viscosity of a liquid.
In foods, xanthan gum is common in salad dressings and sauces.
Xanthan gum helps to prevent oil separation by stabilizing the emulsion, although Xanthan gum is not an emulsifier.

Xanthan gum also helps suspend solid particles, such as spices.
Xanthan gum helps create the desired texture in many ice creams.
Toothpaste often contains xanthan gum as a binder to keep the product uniform.

Xanthan gum also helps thicken commercial egg substitutes made from egg whites, to replace the fat and emulsifiers found in yolks.
Xanthan gum is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages at typical use levels.
In gluten-free baking, xanthan gum is used to give the dough or batter the stickiness that would otherwise be achieved with gluten.
In most foods Xanthan gum is used at concentrations of 0.5% or less.

Xanthan gum is used in a wide range of food products, such as sauces, dressings, meat and poultry products, bakery products, confectionery products, beverages, dairy products, and others.
In the oil industry, xanthan gum is used in large quantities to thicken drilling mud.
These fluids carry the solids cut by the drilling bit to the surface.

Xanthan gum provides great "low end" rheology.
When circulation stops, the solids remain suspended in the drilling fluid.
The widespread use of horizontal drilling and the demand for good control of drilled solids has led to its expanded use.
Xanthan gum has been added to concrete poured underwater, to increase its viscosity and prevent washout.

In cosmetics, xanthan gum is used to prepare water gels.
Xanthan gum is also used in oil-in-water emulsions to enhance droplet coalescence.
Xanthan gum is under preliminary research for its potential uses in tissue engineering to construct hydrogels and scaffolds supporting three-dimensional tissue formation.
Furthermore, thiolated xanthan gum (see thiomers) has shown potential for drug delivery, since by the covalent attachment of thiol groups to this polysaccharide high mucoadhesive and permeation enhancing properties can be introduced.

Xanthan gum is used in food production to improve the texture, consistency and shelf-life of foods such as salad dressings, soups, sauces and baked goods.
Xanthan gum is particularly useful for those with coeliac disease or non-coeliac gluten sensitivity who must follow a gluten-free diet.

This is because gluten-free substitutes for wheat flour need additives like xanthan gum to achieve a product that resembles the texture, crumb and lightness of regular bakes.
Xanthan gum does this by thickening and binding starches to help trap air and mimic the elastic properties of gluten.
Xanthan gum is purchased in powder form and dissolves easily in water.

Xanthan gum is not just found in the kitchen, however – you’ll also find it in your bathroom cabinet. Items like toothpaste, face creams, shampoos and body lotions may all contain xanthan gum.
Xanthan gum helps emulsify and thicken these products, making them more visually appealing and easier to squeeze out or pour.


Shear thinning:
The viscosity of xanthan gum solutions decreases with higher shear rates.
This is called shear thinning or pseudoplasticity.
This means that a product subjected to shear, whether from mixing, shaking or chewing will thin. When the shear forces are removed, the food will thicken again.

In salad dressing, the addition of xanthan gum makes it thick enough at rest in the bottle to keep the mixture fairly homogeneous, but the shear forces generated by shaking and pouring thins Xanthan gum, so it can be easily poured.
When Xanthan gum exits the bottle, the shear forces are removed and Xanthan gum thickens again, so it clings to the salad.

Amounts used:
The greater the ratio of xanthan gum added to a liquid, the thicker the liquid will become.
An emulsion can be formed with as little as 0.1% (by weight).
Increasing the amount of gum gives a thicker, more stable emulsion up to 1% xanthan gum

A teaspoon of xanthan gum weighs about 2.5 grams and brings one cup (250 ml) of water to a 1% concentration.
To make a foam, 0.2–0.8% xanthan gum is typically used.
Larger amounts result in larger bubbles and denser foam.
Egg white powder (0.2–2.0%) with 0.1–0.4% xanthan gum yields bubbles similar to soap bubbles.


Today it is commonly used in:
• Supplements
• Cosmetics
• Baked goods and pastry fillings
• Ice cream and sherbet
• Industrial products
• Jams, jellies and sauces
• Lotions
• Medicines
• Pudding
• Salad dressings
• Toothpastes
• Yogurt

APPLICATIONS OF XANTHAN GUM:
Xanthan gum thickens without the application of heat, which distinguishes it from certain other thickening agents, such as cornstarch and gelatin.
Xanthan gum also retains its thickening properties when cooled, and it is tasteless—features that make it especially useful for canned foods and shelf-stable foods like soups, sauces, gravies, and salad dressings.
Xanthan gum commonly is used with other thickening agents, including guar gum, locust bean gum, carrageenan, gelatin, agar, and pectin.
Xanthan gum may also be paired with starches, such as potato starch, which amplifies its thickening and gelling effects.

As an emusifier, xanthan gum affects viscosity by aiding emulsification and keeps particles from clumping and settling.
Xanthan gum also allows pourable foods, such as salad dressings and barbecue sauces, to flow consistently from their containers.
A very small percentage of xanthan gum—as little as 0.1 percent by weight of the finished product—is needed to produce thickening and emulsifying effects.

The application of xanthan gum as a gelling agent can be seen in jams and jellies.
Xanthan gum is also common in dairy products and ice cream, where it contributes to texture, creating a smooth and creamy mouthfeel by helping to inhibit the formation of water crystals.
Xanthan gum often is used as an ingredient in gluten-free food products, where Xanthan gum acts as an emulsifier and a binder to replicate the lift, tenderness, and elasticity of gluten in doughs.
Because Xanthan gum attracts water, Xanthan gum also helps baked goods retain moisture.

Other applications of xanthan gum include use as a suspension agent in certain medications, such as antibiotics, to ensure proper dosing.
Xanthan gum is also found in personal care products, such as makeup, lotions, and shampoos.
Xanthan gum is slowly replacing carboxymethyl cellulose as a more affordable primary hydrocolloid in toothpaste, where Xanthan gum provides consistency so that the gel can be squeezed from the tube in a solid strand; it also enables the gel to cling to the toothbrush while being spread on teeth.

In the petroleum industry, xanthan gum is added to mud during the hydraulic fracturing process.
When added to drilling mud, because of its thickening properties, xanthan gum facilitates the movement of drill cuttings—pieces of rocks and other solid materials that are removed from boreholes when drilling wells—up to the surface for disposal.
Xanthan gum is also used in some industrial products, including use as a glue in wallpaper paste and as a stabilizer in paint.



PREPARATION OF XANTHAN GUM:
Xanthan gum is produced by the fermentation of glucose and sucrose.
The medium is well-aerated and stirred, and the xanthan polymer is produced extracellularly into the medium.
After one to four days, the polymer is precipitated from the medium by the addition of isopropyl alcohol, and the precipitate is dried and milled to give a powder that is readily soluble in water or brine.

It is composed of pentasaccharide repeat units, comprising glucose, mannose, and glucuronic acid in the molar ratio 2:2:1.

A strain of X. campestris has been developed that will grow on lactose - which allows it to be used to process whey, a waste product of cheese production.
This can produce 30 g/L of xanthan gum for every 40 g/L of whey powder.
Whey-derived xanthan gum is commonly used in many commercial products, such as shampoos and salad dressings.

Detail of the biosynthesis:
Synthesis originates from glucose as substrate for synthesis of the sugar nucleotides precursors UDP-glucose, UDP-glucuronate, and GDP-mannose that are required for building the pentasaccharide repeat unit.
This links the synthesis of xanthan to carbohydrate metabolism.
The repeat units are built up at undecaprenylphosphate lipid carriers that are anchored in the cytoplasmic membrane.

Specific glycosyltransferases sequentially transfer the sugar moieties of the nucleotide sugar xanthan precursors to the lipid carriers.
Acetyl and pyruvyl residues are added as non-carbohydrate decorations.
Mature repeat units are polymerized and exported in a way resembling the Wzy-dependent polysaccharide synthesis mechanism of Enterobacteriaceae.
Products of the gum gene cluster drive synthesis, polymerization, and export of the repeat unit.

WHERE IS XANTHAN GUM FOUND?
Xanthan gum is found in food, personal care and industrial products.

Food Products:
Xanthan gum can improve the texture, consistency, flavor, shelf life and appearance of many foods.
Xanthan gum also stabilizes foods, helping certain foods withstand different temperatures and pH levels.
Additionally, Xanthan gum prevents foods from separating and allows them to flow smoothly out of their containers.

Xanthan gum is used frequently in gluten-free cooking since Xanthan gum can provide the elasticity and fluffiness that gluten gives traditional baked goods.

The following are some common foods that contain xanthan gum:
• Salad dressings
• Bakery products
• Fruit juices
• Soups
• Ice creams
• Sauces and gravies
• Syrups
• Gluten-free products
• Low-fat foods

Personal Care Products:
Xanthan gum is also found in many personal care and beauty products.
Xanthan gum allows these products to be thick, but still flow easily out of their containers.
Xanthan gum also allows solid particles to be suspended in liquids.

The following are some common products that contain xanthan gum:
• Toothpaste
• Creams
• Lotions
• Shampoo
Industrial Products:
Xanthan gum is used in many industrial products due to its ability to withstand different temperatures and pH levels, cling to surfaces and thicken liquids, all while maintaining good flow.

Common industrial products containing xanthan gum include:
• Fungicides, herbicides and insecticides
• Tile, grout, oven and toilet bowl cleaners
• Paints
• Fluids used in oil drilling
• Adhesives like wallpaper glue

HEALTH BENEFITS OF XANTHAN GUM:
Xanthan gum has been linked to other potential health benefits, though these benefits are unlikely to occur without taking supplements.

Some potential health benefits of xanthan gum include:
Lower cholesterol: A study had five men consume 10 times the recommended amount of xanthan gum per day for 23 days.
Subsequent blood tests found that their cholesterol decreased by 10%

Weight loss: People have noted increased fullness after consuming xanthan gum.
Xanthan gum may increase fullness by delaying stomach emptying and slowing digestion

Cancer-fighting properties: A study in mice with melanoma found that Xanthan gum significantly slowed the growth of cancerous tumors and prolonged life.
No human studies have been completed, so the current evidence is weak

Improved regularity: Xanthan gum increases the movement of water into the intestines to create a softer, bulkier stool that’s easier to pass.
Studies have found that Xanthan gum significantly increases the frequency and amount of stool

Thickens liquids: Xanthan gum is used to thicken liquids for those who have difficulty swallowing, such as older adults or people with neurological disorders

Saliva substitute: Xanthan gum is sometimes used as a saliva substitute for individuals suffering from dry mouth, but studies on its effectiveness have found mixed results

When eaten at reasonably high levels, xanthan gum may have some influence on your gut and the speed of digestive transit.
This is because xanthan gum binds with water and swells once eaten; this increases the levels of fluid in the intestine and stimulates the movement of food in the gut, promoting softer, bulkier stools and potentially relieving constipation.

Xanthan gum is also a soluble fibre that acts as ‘fuel’ for the beneficial bacteria that reside in your gut.
These bacteria are important not just for the health of your gut, but for your wider health and well-being, too.

There are also some suggestions that foods containing xanthan gum (again at high levels) may slow the absorption of sugar from the digestive tract and improve satiety.
These findings are also seen when xanthan gum is added to a carb-rich side dish such as rice, where it lowers the overall Glycaemic Index (GI) of the dish.

Similarly, when consumed at sufficient doses, xanthan gum may have a moderate effect on cholesterol levels, with potentially a 10% reduction.

According to a 2009 article published in the journal International Immunopharmacology, for example, xanthan gum was shown to have cancer-fighting properties.
This study evaluated the oral administration of xanthan gum and discovered that it “significantly retarded tumor growth and prolonged survival” of mice inoculated with melanoma cells.

Xanthan gum-based thickeners were also fairly recently found to help oropharyngeal dysphagia patients swallow because of increased viscosity.
This is a condition in which people have a difficulty emptying food into the esophagus because of abnormalities in muscle or nerves.

Common in stroke victims, this use can help people considerably because Xanthan gum can aid aspiration.
Interestingly, this increased viscosity can help reduce blood sugar spikes when xanthan gum is mixed with fruit juice.
In addition to these few studies, some internet sources claim that xanthan gum is good for the skin and hair as well.

Improves texture and consistency:
Xanthan gum is used in tons of food and drink products to improve taste, texture, and consistency.
Xanthan gum can help give gluten-free baked goods (like breads) a springy texture and keep ice cream smooth and thick.

Helps make food safer to swallow:
Some people have difficulty swallowing foods and drinks. (This can happen if you’ve had a stroke or if you develop multiple sclerosis.)

Xanthan gum can help thicken foods and drinks so you’re less likely to aspirate (accidentally inhale food or a drink into your lungs).

Other potential benefits:
A 2012 study suggested that xanthan gum may help reduce blood sugar levels in people with diabetes when it’s combined with a type of fiber called beta glucan or when it’s added to foods.
But research in this area is limited.
Many of the studies suggesting that xanthan gum is helpful for blood sugar control are small and outdated.

On the other hand, a research review showed that xanthan gum may also have laxative effects when used in high doses, which could be helpful for some folks.
That might not be desirable if you’re not dealing with constipation, though.

HOW DOES XANTHAN GUM WORK ?
Xanthan gum swells in the intestine, which stimulates the intestine to push stool through.
Xanthan gum also seems to slow the absorption of sugar from the digestive tract.

EFFECTIVENESS OF XANTHAN GUM:
Xanthan gum seems to reduce constipation.
Xanthan gum seems to improve swallowing and reduce the risk of aspirating food.

WHY DO PEOPLE TAKE XANTHAN GUM?
Research on the health effects of xanthan gum is limited.
Xanthan gum is commonly used as a food additive with few side effects although bloating and gas has been noted.
People use xanthan gum for different purposes, including to try to treat or manage constipationanddiabetes but more studies are needed to confirm the efficacy.

People withceliac diseasemust avoid a protein called gluten.
This protein is found in many grains, including wheat, barley, and rye, making it a common ingredient in baked goods and pasta.
Gluten makes dough stretchy and it helps create the airy texture of baked goods.
When baking, some people who avoid gluten mix xanthan gum with gluten-free flour to achieve the same effects.
Some people who have trouble swallowing add a product called SimplyThick -- which contains xanthan gum -- to foods and drinks to make them easier to swallow.

CAN YOU GET XANTHAN GUM NATURALLY FROM FOODS?
No. Xanthan gum is a food additive.
Xanthan gum is a common ingredient in processed foods.
Some supermarkets also carry xanthan gum alongside other ingredients for baking or in the natural foods area.

SUBSTITUTES FOR XANTHAN GUM:
A handful of alternatives to xanthan gum can thicken food and ensure an even texture:

Psyllium fiber works well as a binding agent and adds fiber to food.
Chia seeds absorb water and make food more gelatinous.
Gelatin helps moisturize food and maintains an even consistency.

Agar is a vegan alternative to some other thickeners, such as gelatin.
Ground flax seeds can bind food and promote a more even texture.
Potato, arrowroot, or cornstarch can also improve the texture, thickness, and other properties of both cold and baked foods.

Cornstarch: Good ole’ cornstarch makes an excellent stand-in for xanthan gum and can be used as a 1-to-1 replacement in recipes.
Chia seeds and water: If you’ve ever made chia seed pudding, you’re familiar with chia’s thickening abilities.
This gooey mix can be used to replace xanthan gum in a straight-up 1-to-1 ratio.

Gelatin: Gelatin is another popular thickener that can replace xanthan gum in a 2-to-1 ratio. (Just keep in mind that gelatin isn’t a vegan option.)
Agar-agar: This algae-derived product can be used as a thickener when xanthan gum isn’t available. You can sub agar-agar for xanthan gum with a 1-to-1 ratio.
Guar gum: Guar gum is super similar to xanthan gum. If you’re in a pinch, guar gum can replace xanthan gum in recipes in a 3-to-1 ratio.


STORAGE OF XANTHAN GUM:
Store xanthan gum in a sealed container away from heat or moisture.
Xanthan gum can be kept in the cupboard with other baking supplies or anywhere out of direct sunlight.
Keeping xanthan gum in a cool, not-too-hot spot will also help prolong its shelf life.

QUESTIONS AND ANSWERS ABOUT XANTHAN GUM:
What is xanthan gum?
Xanthan gum is a hydrocolloid that stabilizes and thickens foods.

How is xanthan gum made?
Xanthan gum is made from a bacteria found on the leaf surfaces of green vegetables, including broccoli, brussels sprouts, cauliflower, cabbage, kale, rutabaga and turnip.
The bacteria is fermented (much like cheese or wine), then dried and ground into powder.

Why is xanthan gum in my food?
Xanthan gum stabilizes and thickens foods to provide the right texture and flavor delivery.

How long has xanthan gum been used in foods?
Xanthan gum was first discovered in the early 1960s, and was approved for use in foods in 1969.

What foods and beverages contain xanthan gum?
Xanthan gum is used in salad dressings, sauces, beverages, dairy products, syrups, toppings, baked goods, confectioneries and candies, breadings, batter, and low fat spreads.

Is xanthan gum permitted for use in the U.S. and in other countries?
Yes. Xanthan gum first received U.S Food and Drug Administration full food additive approval in 1969.
Kelco (now CP Kelco) petitioned xanthan gum to be added to the food additive list.
The approval was based on a full safety assessment by the US FDA.

Countries around the world have approved xanthan gum as a safe food additive.
Xanthan gum is approved for food use globally, including in Canada, Mexico, Brazil, the European Union, China, Japan and Korea.
Xanthan gum’s safety has also been reviewed and endorsed by the World Health Organization and Food and Agriculture Organization (WHO/FAO).

Can xanthan gum be used in foods marketed as organic, vegetarian, halal or kosher?
Yes. The U.S. Department of Agriculture National Organic Program lists xanthan gum on the National list for use in organic processing in the U.S.
Xanthan gum is also allowable in organic production in other major markets, including the European Union, Canada, and internationally by WHO/FAO Codex Alimentarius Commission guidelines.

Xanthan gum can be verified as vegetarian or vegan by producers.
Xanthan gum can also be halal and kosher certified.

Is xanthan gum gluten-free?
Yes. In fact, xanthan gum is used in many gluten-free foods to create the texture and suspension that gluten often provides.

Why is xanthan gum necessary in foods and beverages?
Xanthan gum provides thickening and suspension.
For example, in a salad dressing that contains spices, xanthan gum helps to suspend the spices as well as maintain a smooth and consistent texture.

How much xanthan gum is used in foods and beverages?
A little bit of xanthan gum goes a long way – you typically find around 0.3% concentration or lower in foods and beverages.
As with most other food additives, only the amount of xanthan gum needed to achieve the desired technological function in a food is used.

Why do some people criticize xanthan gum?
Since xanthan gum is similar in structure to fibers, consuming large quantities can have a laxative effect.
If someone consumes large amounts of any fiber, side effects such as gas and bloating will likely be experienced.
The good news is that xanthan gum is used at such low levels in food products – less than 0.3% in most cases – that side effects are unlikely.

How does the production and use of xanthan gum impact the environment?
Xanthan gum is a sustainable product.
The development and processing of xanthan gum occur in a controlled environment.

Is xanthan gum available to consumers as an everyday food ingredient?
Yes, you can typically find xanthan gum at your local grocery store in the baking aisle.



XANTHAN GUM
XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) IUPAC Name of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) 9H-xanthene Experimental Properties of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) Physical Description of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) DryPowder Cream-coloured powder Solubility of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) Soluble in water. Insoluble in ethanol Chemical formula: (C35H49O29)n XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), widely used in food applications, is a heteropolysaccharide produced by submerged aerobic fermentation using a bacterium named Xanthomonas campestris and forms a sterile fermentation medium with carbohydrate, a suitable nitrogen source, potassium phosphate and other trace elements. The polysaccharide produced at the end of the fermentation step is precipitated using isopropyl alcohol and isolated from the medium. The isolated polysaccharide is then centrifuged and then dried to remove residual isopropyl alcohol. The dried XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is milled to be powdered and packed after being sifted through the sieves. The predominant hexose is D-gluco and D-mannose with D-glucuronic acid and pyruvic acid and is prepared as sodium, potassium or calcium salts and the solutions are neutral The XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), a microbial heteropolysaccharide, consists essentially of a polymer skeleton containing 1,4-linked ß-D-glucose units as in cellulose. In these scaffolded side chains, there is a trisaccharide consisting of one D-glucuronic acid residue between the two D-mannose residues. The polymer also contains 4.7% O-acetyl groups and 3.0-3.5% pu rvric acid as a ketal in the glucose unit. These side chains found in the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), which make up about 60% of the molecule, can gain many physical and chemical properties specific to XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM). Because of the side chains, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) can be completely hydrated even in the cold chain. Furthermore, it is stated that these side chains make XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) resistant to hydrolysis. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) which is soluble in water but not soluble in organic solvents; As rheological control agent in water containing systems and as stabilizer for emulsions and suspensions. Apart from these, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM); These properties of the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) which are easily soluble in 8% of hydrochloric acid, 10% of hydrochloric acid and 25% of phosphoric acid, can be easily dissolved in the solution of sulfuric acid, nitric acid and acetic acid, It can last for months as long as the temperature does not rise. Commercial XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a yellowish powdery substance which is completely soluble in hot or cold water and gives high viscosity solutions at low concentrations. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM)'s aqueous solutions are able to poison up to 50% of some hydrophilic solvents such as ethanol and propylene glycol. The viscosity of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a function of its concentration in its distribution. As with other gauges, the xanthan gauge solenoids also exhibit a pseudo-fluid type. Pseudoplastic fluid type; Mouth sensation, taste perception and suspension formation, which have a significant impact on the formation of properties that affect many sensory qualities. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a distinctive feature that distinguishes the gamma from other gums, as its resistance to temperature and pH is considerably larger. This durability is said to be caused by the side chains in the xanthan molecule being wrapped around the cellulose skeleton. This feature is the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM); Enzymes, acids, bases, high temperatures, freezing and thawing, and degradation that can occur during long-term mixing. Interaction of these trisaccharide chains with the main chain makes the molecule a very solid rod and increases the stability of heat, acid and base remarkably. Molecular weight is around 2 million and probably larger values are reported due to aggregation. Pyruvic acid content has the highest xanthans, highest viscosity and thermal stability. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) solvers; Are generally not affected by changes in pH value and are soluble in most of the acids and bases. Most of the other hydrocolloids; Low pH values and viscosity at high temperatures, while XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is stable under the same conditions. Features and benefits of the Xanthan range; To form visible clear solutions even at high concentrations, • dissolving in both hot and cold water, • give high viscosity to solutions even at low polysaccharide concentrations, • minimal change in the viscosity of the solutions formed by xanthan over a wide temperature range, • dissolution and stability in both acidic and alkaline solutions, • stability in solutions with high salt concentration, • high resistance to enzymatic degradation, • a good lubricant, • stability after freezing / thawing steps, • it is an extremely effective emulsion stabilizer, • excellent mouth taste, • can be counted as having synergistic properties with other hydrocolloids (guar and locust bean gum). As food application areas; • sauces and salad dressings, • bakery and pastry products, •meat products, •drinks, • fruit preparations, • powder products are in place. Because the viscosity of the solution does not change much with temperature, that is, when it is cooled it does not increase in consistency, so XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), salad sauces and chocolate syrups are very suitable for use in products that will be consumed as soon as they are removed from the refrigerator. These products should be as easy to pour as they are at room temperature as soon as they leave the refrigerator. In normal salad sauces, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used as a thickener and the particles stabilize suspension in the structure and emulsion in water. The XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM)is generally used in combination with the propylene glycol alginate. When used together they give a solution with less pseudoplasticity and less viscosity. The resulting product has improved pourability and a cream-like smooth structure. Anthan gum; Conforms to other hydrocolloids; Especially locust bean gum and konjacla (gel formation) and guar gum (high viscosity). XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) and guar gamma / gum gamma combinations are used in the stabilization of ice cream and frozen products. This addition of carrageenan prevents the separation of the liquid phase during freezing. Double or triple combinations of these scales are used in various dairy products. Finally, it is used in technical fields in toothpaste, cosmetics, cleaning products, coatings and dyes and fire extinguishers. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a polysaccharide obtained from fermentation of glucose or sucrose with Xanthomonas campestris bacteria. Stabilizer and thickener additive are used as additives. The most important feature of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is its ability to increase consistency even at low concentrations. Use of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) To create visible clear solutions even at high concentrations, Both hot and cold water dissolution, It gives high viscosity to solutions even at low polysaccharide concentrations, Minimal changes in the fluidity of the solutions formed by xanthan in the wide temperature range, The dissolution and stability in both acidic and alkaline solutions, Stability in solutions with high salt concentration, Being a good lubricant, After the freezing / thawing steps, It is an extremely effective emulsion stabilizer, Excellent mouthfeel. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is known as E415 and is used as a stabilizer and thickening additive in food production. One of the most remarkable properties of xanthan gum is its ability to increase its consistency even at very low concentrations. Most food products use 0.5%, even 0.05% Bread, pastry and candies we made with gluten-free flour usually begin to disintegrate and crumble after a short period of time. The duration of the hold is very short. It also does not have the elasticity of products made with normal flours. Food industry Application area tackifier Confectionery sugar and jellies Binding material Coating material Pastry, bakery products emulsifier Salad dressing Create a movie Protective layers, sausage coating Foam fixing XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used as a thickener and stabilizer in the pharmaceutical and food industry. Suspensions are also used as suspending agent, emulsifier, structuring agent or foam enhancer. powdered drink mixes produced in a similar manner sahlep and among our traditional products, ice cream, salad dressings, powdered soups, mayonnaise, is used in various products such as ketchup. It is the reason for preference in the food industry in terms of high consistency which can be achieved especially in the products by extracting the aroma to the foreground and even at the lowest usage rate. In the pharmaceutical industry, tablet binding (adhesive) is used. Food: food, bakery products, bakery products filler, gels and mixtures thereof, batter mixes, biscuit filling, bread, brine solution ham injection, cake mixes, cakes, canned foods, spread cheese, chewing gum, chocolate sauce, coleslaw ornament, confectionery, cottage cheese, cream cheese, dairy products, sweet cream, dessert mixes, desserts / foams, diet products, eggs displacer, reduced-fat margarine, foams, cold soda, frozen food, fruit filling, fruit preparations, gluten-free bread, meat water, ham pumping, ice cream, icings, instant products, prepared soups, liquid / foam powders, Louisiana style hot sauce, mayonnaise, meat batter, the milk shake, filo pastry, pizza sauce, prepared foods, frozen pasta, salad dressings , Sauces, sausages, soft biscuits, sausages, soy sauce, ready-to-eat chocolate drink, sugar eşni are, tomato ketchup, whipped cream and yogurt. Soft drinks: citrus drinks, dietsal soft drinks, fruit juices, fruit flavors and prepared drinks. Drugs: Liquid antibiotics, lozenges, drug emulsions, drug suspensions, syrups, tablets, tablets that delay the release of drug (drug). Personal care: Cosmetics, creams, liquid make-up materials, liquid soap, lotions, shampoos, toiletries, toothpaste. Cleaners / detergents: Acidic cleaners, alkaline cleaners, domestic cleaners, liquid toilet cleaners. Industrial applications: adhesives, agrochemicals, animal feed, bitumen emulsions, calf fillers, ceramic glazes, inks, fire fighting foams, foundry coatings, latex emulsions, latex paints, liquid animal feed, lubricants, metal polishes, mining oil drilling, paint remover material, paper, pet food, wax emulsions, poultry feed, pickling, silicate paints, textiles and carpet dyeing (printing) pastes, fabric (cloth) coatings, water-based paints. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) beauty products and liquid soap, tooth paste, which kullanılır.şampu as a thickener in cosmetic products such as colognes, lotions, cosmetics and hair care products by bazılarıdır.ayrı the cosmetic product prepared with xanthan gain XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) to the cream and to add a feeling of pleasant touch aftershave Can also be used. Use of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) in the Pharmaceutical Sector: XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used in the pharmaceutical sector to regulate the effects of drugs such as antibiotics and to ensure regular dosing. It also helps to stabilize creams containing medicinal chemicals. Agriculture and other sectors XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) industry has a wide range of uses as a thickener and stabilizer. It increases the fluidity of fungicides, herbicides and insecticides. Unique density properties of xanthan solutions increase sprayability, reduce friction and increase the viscosity and permanence of the herbicides. Above all, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a complex exopolysaccharide, i.e. a polymer containing sugar residues secreted by the environment surrounding it by a microorganism. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) produced by plant pathogenic bacteria, a microorganism that causes various diseases in plants, is widely used as a thickener and stabilizing agent in food and industrial products in a wide range. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is widely used today. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) / E-415 Carbohydrate is a high molecular polysaccharide chain produced by a pure culture fermentation with Xanthomonas campestris. It is classified as hydrophilic colloids and their derivatives as a gum. In addition to its utility as an aqueous viscosity enhancer, it is used as a binder, emulsion stabilizer, and various skin conditioning agents and emulsifying surfactants. Stable in solutions containing high concentrations of salt, resistant to enzymatic degradation. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) exhibits extraordinary and useful features. For example; High viscosity at low concentrations, little change in viscosities at varying temperatures, and excellent stability over a wide pH range. It also allows good freeze-thaw stability and exhibits remarkable suspension characteristics. Main functions: Stabilizes emulsions, prevents clotting, improves adhesion, improves texture, gives creamy density, improves mouth feel, improves texture, gives viscosity, stabilizes insoluble ingredients, stabilizes fruit juice in soft drinks, It provides emulsion and foam stability, controls sedimentation, controls drift and adhesion, provides easy flow and pumpability, controls crystallization, provides finer porous structure, increases pitting volume, controls rheology, provides temperature and pH stability, binds water, Allows delayed release of the drug, gives a pleasant skin feel, keeps the active ingredients in suspension, prolongs contact time. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) Product Details: XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a polysaccharide obtained from fermentation of glucose or sucrose with Xanthomonas campestris bacteria. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is known as E415 and it is used as stabilizer and thickener additive in food production. The chemical formula is (C35H49O29) n. The molecular weight is about 10,000. The pH of the 1% solution is 7.3. The XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), which is a microbiological heteropolysaccharide, is composed of a main polymer skeleton containing 1,4-linked ß-glucoside units as in cellulose. In these scaffolded side chains, there is a trisaccharide composed of Dglucoric acid residues between the two D mannose residues. The polymer also contains 4.7% of the acetyl groups and 3.03.5% of the pyruvic acid. These side chains found in the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), which make up about 60% of the molecule, give many physical and chemical properties specific to XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM). Because of the side chains, the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) can be completely hydrated even in the cold chain. In addition, these side chains are said to make the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) resistant to hydrolysis. One of the most remarkable properties of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is its ability to increase its consistency even at very low concentrations. Most food products use 0.5%, or even 0.5%. The pseudoelasticity he carries maintains his determination despite his slick sensation in his mouth. Unlike other gamut types, it is stable in large temperature and pH changes and is considered a reliable additive in America, Canada and Europe. Stable in solutions containing high concentrations of salt, resistant to enzymatic degradation. Features and benefits of xantan gamut; Soluble in both hot and cold water, giving high viscosity to solutions even at low polysaccharide concentrations, Minimal change in the fluidity of solutions formed by xanthan in wide temperature range, Solubility and stability in both acidic and alkaline solutions Stability of solutions with high salt concentration, Good lubricity, Stability after frost / dissolution stages, Excellent emulsion stabilizer, Excellent mouth taste. Applications of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) in the Cosmetic Industry: XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM)Features: Carbohydrate is a high molecular polysaccharide chain produced by a pure culture fermentation with Xanthomonas campestris. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is classified as hydrophilic colloids and their derivatives as a gum. In addition to its utility as an aqueous viscosity enhancer, it is used as a binder, emulsion stabilizer, and various skin conditioning agents and emulsifying surfactants. Stable in solutions containing high concentrations of salt, resistant to enzymatic degradation. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) exhibits extraordinary and useful features. For example; High viscosity at low concentrations, little change in viscosities at varying temperatures, and excellent stability over a wide pH range. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) also allows good freeze-thaw stability and exhibits remarkable suspension characteristics. Major functions / characteristics: Stabilizes emulsions, prevents clotting, provides good adhesion, improves texture, improves mouth feel, improves mouthfeel, gives added viscosity, stabilizes insoluble components, stabilizes fruit juice in soft drinks, provides emulsion and foam stability Control sedimentation, control drift and adhesion, provide easy flow and pumpability, control crystallization, provide finer porous structure, increase pitting volume, control rheology, provide temperature and pH stability, bind water, allow delayed drug release in medication Gives a pleasant skin feel, keeps the active ingredients in suspension, prolongs contact time. Industrial applications of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM): adhesives, agrochemicals, animal feed, bitumen emulsions, calf fillers, ceramic glazes, inks, fire fighting foams, foundry coats, latex emulsions, latex paints, liquid animal feed, lubricants, metal polishes, mining, oil Punching, paint remover, paper, pet food, lacquer emulsions, poultry feed, rust removers, silicate dyes, textile and carpet dyeing (printing) adhesives, textile coatings, water based paints. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a sugar-like compound made by mixing aged (fermented) sugars with a certain kind of bacteria. It is used to make medicine. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used for lowering blood sugar and total cholesterol in people with diabetes. It is also used as a laxative. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is sometimes used as a saliva substitute in people with dry mouth (Sjogren's syndrome). In manufacturing, xanthan gum is used as a thickening and stabilizing agent in foods, toothpastes, and medicines. Xanthan gum is also an ingredient in some sustained-release pills. PH 6.0 - 8.0 COLOR White to cream APPEARANCE Free flowing powder INDUSTRY Food Chemicals, Industrial, Industrial Drilling, Oil and Gas Production, Drilling Fluid, Hydraulic Fracturing, Fracking One of the most remarkable properties of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is its ability to produce a large increase in the viscosity of a liquid by adding a very small quantity of gum. The viscosity solutions decrease with higher shear rates, which is called pseudoplasticity. This means that a product subjected to shear, whether from mixing, shaking, or even chewing, will thin out, but once the shear forces are removed, the food will thicken back up. In foods, this gum is used as a good thickening agent which is most often found in salad dressings and sauces. It makes these products thick enough at rest in the bottle to keep the mixture fairly homogeneous, but the shear forces generated by shaking the mixture so it can be easily poured. When it exits the bottle, the shear forces are removed and the mixture thickens back up, so it clings to the salad or food. It is very stable under a wide range of temperatures and pH. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier. This gum also helps suspend solid particles, such as spices. Also used in frozen foods and beverages, it helps create the pleasant texture in many ice creams.Gluten-free baking also contains this ingredient; since the gluten found in wheat must be omitted, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used to give the dough or batter a "stickiness" that would otherwise be achieved with the gluten. It is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages. In personal care, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a stabilizer to prevent ingredients from separating. In toothpaste, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) serves as a binder to keep the product uniform. It is also used to prepare water gel, oil-in-water emulsions to help stabilize the oil droplets against coalescence, and has some skin hydrating properties. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is a high molecular weight polysaccharide produced by fermentation of Xanthamonas campestris. The composition and structure of the XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) produced by commercial fermentation is identical to the naturally occurring polysaccharide formed on plants belonging to the cabbage family. Process control and rigorous quality standards throughout production guarantee consistent, reliable product performance. In processed foods, xanthan gum provides stability and improves or modifies textural qualities, pouring characteristics and cling. Exceptional thickening and stabilizing abilities make XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) products a common component in many food systems. For salad dressings, ACAR products are the stabilizers of choice, keeping ingredients suspended uniformly while providing excellent pourability without flavor masking. The dramatic thickening capability of low concentrations of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) provides improved mouthfeel in products such as syrups and powdered juice drinks. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) (/ˈzænθən/) is a polysaccharide with many industrial uses, including as a common food additive. It is an effective thickening agent and stabilizer to prevent ingredients from separating. It can be produced from simple sugars using a fermentation process, and derives its name from the species of bacteria used, Xanthomonas campestris. Contents 1 History of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) 2 Uses of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) 2.1 Shear thinning 2.2 Amounts used 3 Health 3.1 Safety of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) 4 Preparation of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) 4.1 Detail of the biosynthesis 5 References History of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) was discovered by Allene Rosalind Jeanes and her research team at the United States Department of Agriculture, and brought into commercial production by CP Kelco under the trade name Kelzan® in the early 1960s.[2][3] It was approved for use in foods in 1968 and is accepted as a safe food additive in the USA, Canada, European countries, and many other countries, with E number E415, and CAS number 11138-66-2. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) derives its name from the species of bacteria used during the fermentation process, Xanthomonas campestris.[4] This is the same bacterium responsible for causing black rot to form on broccoli, cauliflower, and other leafy vegetables. Uses of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM), 1%, can produce a significant increase in the viscosity of a liquid.[5] In foods, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is common in salad dressings and sauces. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) also helps suspend solid particles, such as spices. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) helps create the desired texture in many ice creams. Toothpaste often contains XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) as a binder to keep the product uniform. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) also helps thicken commercial egg substitutes made from egg whites, to replace the fat and emulsifiers found in yolks. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages at typical use levels.[6] In gluten-free baking, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used to give the dough or batter the stickiness that would otherwise be achieved with gluten. In most foods XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used at concentrations of 0.5% or less. Xanthan gum is used in wide range food products, such as sauces, dressings, meat and poultry products, bakery products, confectionery products, beverages, dairy products, others. In the oil industry, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used in large quantities to thicken drilling mud.[7] These fluids carry the solids cut by the drilling bit to the surface. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) provides great "low end" rheology. When circulation stops, the solids remain suspended in the drilling fluid. The widespread use of horizontal drilling and the demand for good control of drilled solids has led to its expanded use. XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) has been added to concrete poured underwater, to increase its viscosity and prevent washout. In cosmetics, XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is used to prepare water gels.[8] It is also used in oil-in-water emulsions to enhance droplet coalescence.[9] Xanthan gum is under preliminary research for its potential uses in tissue engineering to construct hydrogels and scaffolds supporting three-dimensional tissue formation.[8] Shear thinning The viscosity of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) solutions decreases with higher shear rates. This is called shear thinning or pseudoplasticity. This means that a product subjected to shear, whether from mixing, shaking or chewing will thin. When the shear forces are removed, the food will thicken again. In salad dressing, the addition of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) makes it thick enough at rest in the bottle to keep the mixture fairly homogeneous, but the shear forces generated by shaking and pouring thins it, so it can be easily poured. When it exits the bottle, the shear forces are removed and it thickens again, so it clings to the salad. Amounts used The greater the ratio of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) added to a liquid, the thicker the liquid will become. An emulsion can be formed with as little as 0.1% (by weight). Increasing the amount of gum gives a thicker, more stable emulsion up to 1% XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM). A teaspoon of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) weighs about 2.5 grams and brings one cup (250 ml) of water to a 1% concentration.[6][10] To make a foam, 0.2–0.8% XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is typically used. Larger amounts result in larger bubbles and denser foam. Egg white powder (0.2–2.0%) with 0.1–0.4% XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) yields bubbles similar to soap bubbles. Health Evaluation of workers exposed to XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) dust found evidence of a link to respiratory symptoms.[11] On May 20, 2011, the FDA issued a press release about SimplyThick, a food-thickening additive containing XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) as the active ingredient, warning parents, caregivers and health care providers not to feed SimplyThick, a thickening product, to premature infants.[12] The concern is that the product may cause premature infants to suffer necrotizing enterocolitis. Safety of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) According to a 2017 safety review by a scientific panel of the European Food Safety Authority (EFSA), XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) (European food additive number E 415) is extensively digested during intestinal fermentation, and causes no adverse effects, even at high intake amounts.[13] The EFSA panel found no concern about genotoxicity from long-term consumption.[13] EFSA concluded that there is no safety concern for the general population when XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is consumed as a food additive.[13] Preparation XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is produced by the fermentation of glucose and sucrose.[13] The polysaccharide is prepared by the bacteria being inoculated into a sterile aqueous solution of carbohydrate(s), a source of nitrogen, dipotassium phosphate, and some trace elements.[13] The medium is well-aerated and stirred, and the xanthan polymer is produced extracellularly into the medium. After one to four days, the polymer is precipitated from the medium by the addition of isopropyl alcohol, and the precipitate is dried and milled to give a powder that is readily soluble in water or brine.[13] XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is composed of pentasaccharide repeat units, comprising glucose, mannose, and glucuronic acid in the molar ratio 2:2:1.[13][14] A strain of X. campestris has been developed that will grow on lactose - which allows it to be used to process whey, a waste product of cheese production. This can produce 30 g/L of XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) for every 40 g/L of whey powder. Whey-derived XANTHAN GUM (Ksantan Sakızı)(KSANTAN GAM) is commonly used in many commercial products, such as shampoos and salad dressings.[15] Detail of the biosynthesis Synthesis originates from glucose as substrate for synthesis of the sugar nucleotides precursors UDP-glucose, UDP-glucuronate, and GDP-mannose that are required for building the pentasaccharide repeat unit.[13] This links the synthesis of xanthan to carbohydrate metabolism. The repeat units are built up at undecaprenylphosphate lipid carriers that are anchored in the cytoplasmic membrane.[citation needed] Specific glycosyltransferases sequentially transfer the sugar moieties of the nucleotide sugar xanthan precursors to the lipid carriers. Acetyl and pyruvyl residues are added as non-carbohydrate decorations. Mature repeat units are polymerized and exported in a way resembling the Wzy-dependent polysaccharide synthesis mechanism of Enterobacteriaceae. Products of the gum gene cluster drive synthesis, polymerization, and export of the repeat unit.
XANTHAN GUM (e415)
Xanthan gum (e415) is then dried and turned into a powder.
Xanthan gum (e415) is a popular food additive that’s commonly added to foods as a thickener or stabilizer.


CAS Number:11138-66-2
EC Number: 234-394-2
MDL number: MFCD00131256
Molecular Formula: (C35H49O29)n



SYNONYMS:
Gum xanthan, E415, Natural Xanthan Gum, Stabilizer (415), Stabilizer (E415), Thickening Agent (E415), Thickening Agent (INS 415), Vegetable Gum (415), Vegetable Gum (E415), E415, Edible Gum (E415), Emulsifier (E415), Emulsifier (INS 415), Emulsifier & Stabilizers E415, Emulsifying & Stabilizing Agent (INS 415), Emulsifying & Stabilizing Agents (E415), Emulsifying agent E415, Food Grade Xanthan Gum (Stabilising Agent E415), Gum Blend (Xanthan Gum, Guar Gum)



Xanthan gum (e415) is a popular food additive that’s commonly added to foods as a thickener or stabilizer.
Xanthan gum (e415)’s created when sugar is fermented by a type of bacteria called Xanthomonas campestris.
When sugar is fermented, Xanthan gum (e415) creates a broth or goo-like substance, which is made solid by adding an alcohol.


Xanthan gum (e415) is then dried and turned into a powder.
When Xanthan gum (e415) powder is added to a liquid, it quickly disperses and creates a viscous and stable solution.
This makes Xanthan gum (e415) a great thickening, suspending and stabilizing agent for many products.


Xanthan gum (e415) was discovered by scientists in 1963.
Since then, Xanthan gum (e415) has been well researched and determined safe.
Therefore, the FDA has approved it as a food additive and placed no limitations on the amount of Xanthan gum (e415) a food can contain.


Even though Xanthan gum (e415)’s made in a lab, it’s a soluble fiber.
Xanthan gum (e415) is soluble fibers are carbs that your body cannot breakdown.
Instead, they absorb water and turn into a gel-like substance in your digestive system, which slows digestion.


Therefore, your body is unable to digest Xanthan gum (e415), and it does not provide any calories or nutrients.
Xanthan gum (e415), a high molecular weight polysaccharide, is a popular food additive that is frequently used as a thickener and emulsifier in various food products including bread, sauces, cake, etc.


Xanthan gum (e415) thickener is a normal powder produced by fermentation of corn starch and bean protein with Xanthomonas campestris.
Xanthan gum (e415) is a vital ingredient in the food industry, and its benefits are notable.
With its versatility and effectiveness as a thickener and stabilizer, the use of Xanthan gum (e415) in food and Xanthan gum (e415) for sale is guaranteed to enhance the quality of any food product, whether it's created in a commercial kitchen or a home kitchen.


Xanthan gum (e415) sauce thickener, due to its excellent thickening and stabilizing properties, is widely used in the food industry for preparing a variety of sauces, including salad dressings, marinades, and gravies.
Moreover, Xanthan gum (e415) emulsifier means it helps to combine oil and water-based ingredients that are usually separate from each other.


Therefore, Xanthan gum (e415) emulsifiers and thickeners are used in a wide range of food products like beverages, dairy products, bakery goods, and more.
An additive used as a thickener, stabiliser and emulsifier, Xanthan gum (e415) is made when strains of the Xanthomonas campestris bacteria are fed a solution of glucose, derived from corn, soy, dairy or wheat.


The bacteria ferments the sugary solution, creating a sticky protective coat that has a consistency suitable for binding and thickening ingredients.
It's these properties that make Xanthan gum (e415) useful in food production – most notably in gluten-free baking, where it helps starches combine and improves the rise of gluten-free bakes.


The food additive, Xanthan gum (e415), is a substance that acts as an emulsifier, stabiliser, thickener, filler and binder.
Xanthan gum (e415) is a fermentation gum.
Chemically Xanthan gum (e415) is a high molecular weight polysaccharide obtained by aerobic fermentation of glucose in pure culture at ph = 6,0-7,5 and 28-30o C by the bacterium Xantomonas Campestris.


After fermentation, the biosynthesized mass is purified by extraction with ethanol, or with propan-2-ol, then dried and ground.
Contains D-glucose and D-mannose, D-glucuronic acid and pyruvic acid.
Xanthan gum (e415) is obtained as potassium, sodium or calcium salts.


The bacterial strains used in Xanthan gum (e415) production are the most efficient for it production.
Some of these strains are commercially available.
The composition of the nutrient medium used in Xanthan gum (e415) production is adjusted to contain the nutrients required for Xanthan gum (e415) production.


Xanthan gum (e415) production is an important process used in food, cosmetics and industrial products. Xanthan gum (e415) production is a high efficiency and low cost process.
Xanthan gum (e415) is a popular food additive that’s commonly added to foods as a thickener or stabilizer.


Xanthan gum (e415)’s created when sugar is fermented by a type of bacteria called Xanthomonas campestris.
When sugar is fermented, Xanthan gum (e415) creates a broth or goo-like substance, which is made solid by adding an alcohol.
Xanthan gum (e415) is then dried and turned into a powder.


When Xanthan gum (e415) is added to a liquid, it quickly disperses and creates a viscous and stable solution.
This makes Xanthan gum (e415) a great thickening, suspending and stabilizing agent for many products.
Xanthan gum (e415) was discovered by scientists in 1963.


Since then, Xanthan gum (e415) has been well researched and determined safe.
Therefore, the FDA has approved it as a food additive and placed no limitations on the amount of Xanthan gum (e415) a food can contain.
Even though Xanthan gum (e415)’s made in a lab, it’s a soluble fiber.


Soluble fibers are carbs that your body cannot breakdown.
Instead, they absorb water and turn into a gel-like substance in your digestive system, which slows digestion (3Trusted Source).
Therefore, your body is unable to digest Xanthan gum (e415), and it does not provide any calories or nutrients.


Xanthan gum (e415), also known as corn sugar gum, is a naturally occurring polysaccharide obtained from the fermentation of glucose or sucrose by the bacterium Xanthomonas campestris.
Xanthan gum (e415) is approved in the EU as a food additive under the number E415.


The human organism cannot metabolize Xanthan gum (e415), which is why it can be counted among dietary fibers.
Xanthan gum (e415) is a type of polysaccharide.
Xanthan gum (e415) is produced by aerobic fermentation of sugars by the bacterium Xanthomonas campestris.


Xanthan gum (e415) (/ˈzænθən/) is a polysaccharide with many industrial uses, including as a common food additive.
Xanthan gum (e415) is an effective thickening agent and stabilizer that prevents ingredients from separating.
Xanthan gum (e415) can be produced from simple sugars by fermentation and derives its name from the species of bacteria used, Xanthomonas campestris.


Xanthan gum (e415) derives its name from the species of bacteria used during the fermentation process, Xanthomonas campestris.
Xanthan gum (e415), 1%, can produce a significant increase in the viscosity of a liquid.
Xanthan gum (e415) is a high molecular weight polysaccharide produced by fermentation of a carbohydrate with Xanthomonas campestris.


Xanthan gum (e415) is a high-molecular-weight extracellular polysaccharide widely used as a thickener, emulsifier and stabiliser in food.
Unlike other polysaccharide gums, Xanthan gum (e415) is made from bacterial fermentation rather than extraction from plants.
Xanthan gum (e415) is a cream-coloured, free-flowing powder boasting a neutral flavour taste.


Even at low concentrations, Xanthan gum (e415) solutions offer a higher degree of viscosity than other polysaccharides.
Xanthan gum (e415) solutions are highly pseudoplastic to enhance sensory qualities (flavour release, mouthfeel) and guarantee good pouring.
Xanthan gum (e415) also improves the freeze/thaw stability of frozen foods.


Xanthan gum (e415) is food safe with fine particle size - FF (other grades available).
Xanthan gum (e415) is a natural polysaccharide, cold water soluble product made from the fermentation of carbohydrates.
Xanthan gum (e415) is produced by a biotechnological process involving fermentation of glucose or sucrose by the Xanthomonas campestris bacterium.


Xanthan gum (e415) was discovered by an extensive research effort by the United States Department of Agriculture, which involved the screening of a large number of biopolymers for their potential uses.
One of the most remarkable properties of Xanthan gum (e415) is its capability of producing a large increase in the viscosity of a liquid by adding a very small quantity of gum of the order of one percent.


Unlike other gums Xanthan gum (e415) is very stable under a wide range of temperatures and pH, and is accepted as a safe food additive in USA and Europe.
Xanthan gum (e415) will prevent ice crystals from forming in homemade ice cream.
Xanthan gum (e415)’s also a common ingredient in gluten-free baked goods (cake, pizza, ...).


Xanthan gum (e415) is soluble in hot and cold water.
Xanthan gum (e415) is highly resistant to temperature variations.
Xanthan gum (e415) is a fibrous carbohydrate and a stabilizer with hydrocolloid properties used as a thickening additive.


Xanthan gum (e415) gives high consistency even at very low concentration.
Xanthan gum (e415) is produced by fermenting corn starch with a bacterium (Xanthomonas campestris).
When preparing a vinaigrette for your salad, add a small amount of Xanthan gum (e415).


In this way, without the need to use egg yolk (lecithin), Xanthan gum (e415) will bind your salad dressing and create a sauce by preventing the oil and acid from separating from each other.
Xanthan gum (e415), also known as E415, is a high molecular weight natural polysaccharide containing mainly glucose, mannose and glucuronic acid.


Commercial Xanthan gum (e415) in the form of yellowish powder provides high viscosity to the solution it is added to, even at low concentrations.
Xanthan gum (e415) can improve the structure, consistency, flavor and shelf life of many food items.
Xanthan gum (e415) prevents food from separating and ensures that it flows smoothly from the containers.


Xanthan gum (e415) is a popular food additive added as a food thickener or stabilizer.
Xanthan gum (e415) is an additive frequently used in the food industry.
This naturally soft polysaccharide, Xanthan gum (e415), forms a gel when mixed with water, causing an increase in viscosity.
Xanthan gum (e415) is also known as KSANTAN SAND.



USES and APPLICATIONS of XANTHAN GUM (e415):
Food producers use the odorless, slightly yellowish powder, Xanthan gum (e415), as a gelling agent, thickener and filler.
Applications of Xanthan gum (e415): Baby Food, Bakery, Beverages, Dairy Alternatives, Meat Alternatives, Plant-based Products, Ready Meals, Sauces, Dressings, Seasonings, Confectionery


Xanthan gum (e415) is used as a thickener and emulsifier (rheology modifier) in food products.
Xanthan gum (e415) is used in many foods.
These include desserts, ice cream, milkshakes, jelly, jam, marmalade, sour vegetables, soups, sauces, ketchup, mayonnaise, canned fish, canned meat, baked goods, canned fruit and canned vegetables.


B2B suppliers deliver not only to food manufacturers, but also to medical and cosmetic product companies, as Xanthan gum (e415) is also suitable for shampoos and washing gels, for example.
Xanthan gum (e415) comes in powder form and is widely used in foods, cosmetics and industrial products.


Xanthan gum (e415) Powder in gluten free baking: Xanthan gum (e415), along with guar gum, is one of the main substitutes used in gluten free baking.
Xanthan gum (e415) is used as a food thickening ingredient and a stabilizer, to prevent ingredients from separating.
Xanthan gum (e415) is used mixing with various oils and floating paints for marbelling.


Xanthan gum (e415) is used as a thickener and stabilizer in the pharmaceutical and food industries.
Xanthan gum (e415) is also used in sahleps, one of our traditional products, and powdered drink mixtures produced in a similar style.
In addition to all these, Xanthan gum (e415) is also a source of foods such as ice cream, salad dressings and ketchup.


Food: Xanthan gum (e415) in food can control the rheology, structure, flavor, and appearance of the product, and its pseudo-plasticity can ensure a good taste, so thickener e415 is widely used in salad dressings, bread, dairy products, frozen food, beverages, condiments, brewing, candy, cakes, soups, and canned foods.


Daily chemicals uses of Xanthan gum (e415): Xanthan gum (e415) e415 is used as the main functional ingredient in most high-end cosmetics.
In addition, Xanthan gum (e415) for sale can also be used as a component of toothpaste to substantially thicken and set the shape, reducing tooth surface wear.


Xanthan gum (e415) is also used in pharmaceuticals, as a binder and emulsifier in tablet formulations.
Xanthan gum (e415) can also be added to ice cream to prevent ice crystals from forming.
Xanthan gum (e415) will produce a large increase in the viscosity of a liquid by adding a very small amount (around 1%).


However, in most applications, Xanthan gum (e415) is used at 0.5% or even as low as 0.05%.
In foods, Xanthan gum (e415) is often found in salad dressings and sauces.
Xanthan gum (e415) helps to prevent oil separation by stabilising the emulsion.


Xanthan gum (e415) also helps suspend solid particles, such as spices.
Xanthan gum (e415) is used in frozen foods and beverages, it helps create a pleasant texture in ice creams and does not change the colour or flavour of foods or beverages.


Xanthan gum (e415) is suitable for Vegans & Vegetarians, Non-GMO, Gluten Free.
Xanthan gum (e415) is used stabiliser, emulsifier, thickener and texture improver in sauces and dressings.
Add Xanthan gum (e415) to Agar Agar and Carrageenan Kappa to produce more stable gels.


Xanthan gum (e415) is used in ice cream to improve texture and stop ice crystals from forming.
Xanthan gum (e415) stabilises foams when using a whipper gun, which can be served hot or cold.
Xanthan gum (e415) is used for pastry and pie fillings to prevent weeping of the filling.


Xanthan gum (e415) is suitable for Vegans, Non-GMO, Gluten Free.
Xanthan gum (e415) is used as a thickening and stabilizing agent in foods, to create light foam and hence can be found in sauces, mayonnaise, dressings, coffee, poultry products, confectionery products and in baking is used as a way to achieve gluten-free baking as it provides it with stickiness that gluten wold otherwise provide.


Additionally Xanthan gum (e415) can also be found in toothpastes, in cosmectics it is used to create water-gel based creams and lotions and industrial products like fungicides, herbicides and adhesives.
Xanthan gum (e415) can be used by all religious groups, vegans and vegetarians.


Xanthan gum (e415) is then dried and turned into a powder.
When Xanthan gum (e415) powder is added to a liquid, it quickly disperses and creates a viscous and stable solution.
This makes Xanthan gum (e415) a great thickening, suspending and stabilizing agent for many products.


Xanthan gum (e415) can be used as a thickener or a stabilizer and reheology control agent for food, pharmaceutical, toothpaste.
In food field, Xanthan gum (e415) can be added to beverages, dairy, confectionery, bakery, frozen desserts, meat and etc.


Areas of Use of Xanthan gum (e415): Food, Medicine, Cosmetics, Agriculture, Pet Food, Processed Meat Products, Pastry and Bakery Products, Sauces, Beer, Ice Cream, Pasta, Fruit Juices, Cheese Production Frozen Foods.
Xanthan gum (e415) is used as an important additive in the food industry.


Xanthan gum (e415), also known with the code E415, is used to increase the stability of food products, improve their texture and keep their fluidity under control.
Xanthan gum (e415), a natural polysaccharide, can be used in many food products and offers an alternative solution to consumers with gluten intolerance.


Xanthan gum (e415) is used at a rate of 0.05% - 0.5% in many food products.
Xanthan gum (e415) is often used to stabilize emulsions, increase the viscosity of liquids or control foam formation.
In addition, since Xanthan gum (e415) is a gluten-free alternative, it is frequently preferred in gluten-free or low glycemic index products.


Xanthan gum (e415) is a widely used additive in the food industry.
Xanthan gum (e415) forms a gel when mixed with water, causing an increase in viscosity.
Xanthan gum (e415) is used to stabilize emulsions, increase the viscosity of liquids and control foam formation.


Since Xantham - Gum is a gluten-free alternative, Xanthan gum (e415) is preferred in gluten-free or low glycemic index products.
Xanthan gum (e415), produced through microbial fermentation using Xanthomonas campestris bacteria, has a wide range of uses in the food, pharmaceutical, cosmetics and textile industries.


Xanthan gum (e415); Apart from the food industry, where it is widely used as an additive, it is included in the formulation as a thickener and stabilizer in the production of various products, from textiles to cleaning agents, from pharmaceuticals and cosmetics to paints and inks.
Xanthan gum (e415) is used in the production of low-fat foods.


Xanthan gum (e415) is used in the production of gluten-free products.
Xanthan gum (e415) is used as a stabilizer and thickening additive in food production.
Xanthan gum (e415) gives high consistency even at very low concentration.


Xanthan gum (e415) is used at a rate of 0.05% - 0.5% in many food products.
Xanthan gum (e415)'s E code is (E 415).
Xanthan gum (e415) is used Food, Medicine, Cosmetics, Agriculture, Pet food, Processed Meat Products, Pastry and Bakery Products, Sauces, Beer, Ice Cream, Pasta, Juices, and Cheese Production Frozen Foods,


Xanthan gum (e415) is a natural polysaccharide used as a mixing agent and often found in the food industry.
Xanthan gum (e415) is a substance secreted by the bacterium Xanthomonas campestris, a microorganism obtained through fermentation .
Xanthan gum (e415) has many different functions such as viscosity enhancer, emulsifier and stabilizer.


Xanthan gum (e415) is a mixing agent often used in the food industry.
Xanthan gum (e415) is preferred as a texture additive, especially in the production of gluten-free or low-gluten foods.
Xanthan gum (e415) is also used for various purposes in the pharmaceutical industry, cosmetics industry and other industries.


In foods, Xanthan gum (e415) is common in salad dressings and sauces.
Xanthan gum (e415) helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier.
Xanthan gum (e415) also helps suspend solid particles, such as spices.


Xanthan gum (e415) helps create the desired texture in many ice creams.
Toothpaste often contains Xanthan gum (e415) as a binder to keep the product uniform.
Xanthan gum (e415) also helps thicken commercial egg substitutes made from egg whites, to replace the fat and emulsifiers found in yolks.


Xanthan gum (e415) is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages at typical use levels.
In gluten-free baking, Xanthan gum (e415) is used to give the dough or batter the stickiness that would otherwise be achieved with gluten.


In most foods, Xanthan gum (e415) is used at concentrations of 0.5% or less.
Xanthan gum (e415) is used in a wide range of food products, such as sauces, dressings, meat and poultry products, bakery products, confectionery products, beverages, dairy products, and others.


In the oil industry, Xanthan gum (e415) is used in large quantities to thicken drilling mud.
These fluids carry the solids cut by the drilling bit to the surface.
Xanthan gum (e415) provides improved "low end" rheology. When circulation stops, the solids remain suspended in the drilling fluid.


The widespread use of horizontal drilling and the demand for good control of drilled solids has led to its expanded use.
Xanthan gum (e415) has been added to concrete poured underwater, to increase its viscosity and prevent washout.
In cosmetics, Xanthan gum (e415) is used to prepare water gels.


Xanthan gum (e415) is also used in oil-in-water emulsions to enhance droplet coalescence.
Xanthan gum (e415) is under preliminary research for its potential uses in tissue engineering to construct hydrogels and scaffolds supporting three-dimensional tissue formation.


Furthermore, thiolated Xanthan gum (e415) (see thiomers) has shown potential for drug delivery, since by the covalent attachment of thiol groups to this polysaccharide high mucoadhesive and permeation enhancing properties can be introduced


-Usage of Xanthan gum (e415) in foods:
Xanthan gum (e415) is used as a thickener, stabilizer and emulsifier in foods.
Xanthan gum (e415) is found in many food products such as yoghurt, sauces, soups, ice cream, jam, marmalade, sauces, mayonnaise, salad dressings, sauces, bread, cakes, cookies, chocolate, confectionery, toothpaste and mouthwash.
Xanthan gum (e415) helps improve the consistency and texture of foods, creating a homogeneous texture, preventing them from separating and keeping them fresher longer.


-Usage of Xanthan gum (e415) in cosmetics:
Xanthan gum (e415) is used as a thickener, stabilizer and emulsifier in cosmetics.
Xanthan gum (e415) is found in many cosmetic products such as moisturizers, creams, lotions, shampoos, conditioners, toothpaste, mouthwash, make-up products and cleaning products.
Xanthan gum (e415) helps improve the consistency and texture of cosmetics, creating a homogeneous texture, preventing segregation and keeping them fresher longer.


-Usage of Xanthan gum (e415) in industrial products:
Xanthan gum (e415) is used as a thickener, stabilizer and emulsifier in industrial products.
Xanthan gum (e415) is found in many industrial products such as paints, inks, adhesives, ceramics, textiles, paper, plastic and concrete.
Xanthan gum (e415) helps improve the consistency and structure of industrial products, creating a homogeneous texture, preventing decomposition and keeping them fresher longer.


-Use of Xanthan gum (e415) in the Food Industry:
The Role and Benefits of E415
Xanthan gum (e415), which has an important place among the additives used in the food industry, is also known with the code E415.

Xanthan gum (e415), also called Xantham - Gum, is used especially to improve the texture and increase the stability of food products.
Xanthan gum (e415) is a type of natural polysaccharide and is obtained by fermentation by bacteria.
Xanthan gum (e415) has a special structure that forms a gel and increases viscosity when mixed with water.

Xanthan gum (e415) is used in foods for functions such as forming gels, stabilizing emulsions and increasing fluidity.
The role of Xanthan gum (e415) in the food industry is quite extensive.
Xanthan gum (e415), used in many products such as yoghurt, cheese, sauces, ice cream, bread and bakery products, helps maintain the quality of the products.

In addition, the fact that Xanthan gum (e415) can be used in gluten-free products provides an important advantage, especially for people with gluten intolerance.



WHAT IS XANTHAN GUM (e415) USED FOR?
Xanthan gum (e415) is used in food production to improve the texture, consistency and shelf-life of foods such as salad dressings, soups, sauces and baked goods.
Xanthan gum (e415) is particularly useful for those with coeliac disease or non-coeliac gluten sensitivity who must follow a gluten-free diet.

This is because gluten-free substitutes for wheat flour need additives like Xanthan gum (e415) to achieve a product that resembles the crumb and lightness of regular bakes.
Xanthan gum (e415) does this by thickening and binding starches, mimicking the elastic properties of gluten.

Xanthan gum (e415) is purchased in powder form and dissolves easily in water.
Xanthan gum (e415) is also used in numerous household products, from wallpaper paste to cosmetics.

Items like toothpaste, face creams, shampoos and body lotions may all contain Xanthan gum (e415).
Xanthan gum (e415) helps emulsify and thicken these products, making them more visually appealing and easier to squeeze out or pour.



FUNCTION AND PROPERTIES OF XANTHAN GUM (e415):
Xanthan gum (e415) stabilizes emulsions as its main functional properties.
Xanthan gum (e415) also prevents clotting and ensures good adhesion.

In line with the general structure of Xanthan gum (e415), which stabilizes the fruit essence to a good degree in soft drinks, you will have the opportunity to obtain clear results from the effects of each use.

While Xanthan gum (e415) increases the mouthfeel in emulsions, it also provides finer drift, prevention of sticking and at the same time keeps the active ingredients in suspension.
Considering each of these features, Xanthan gum (e415) provides progress with as effective a structure as possible.



FEATURE OF XANTHAN GUM (e415):
High temperature resistance, freeze-thaw stability, special shear and high emulsification performance; high stability at high temperature, able to maintain the moisture content of baked goods and increase the taste; complete solubility and stability under low PH conditions.



FEATURES AND BENEFITS OF XANTHAN GUM (e415):
*Very low caloric value,
*Highly resistant to enzymatic degradation,
*Excellent freeze/thaw stability,
*Very resistant to pH variations,
*Highly resistant to temperature variations



PRODUCTION OF XANTHAN GUM (e415):
*Raw Materials and Production Process
Xanthan gum (e415) is a natural food additive and is generally used as a thickener and stabilizer in the food industry.
The production process of Xanthan gum (e415) E415 is carried out very meticulously and is achieved by combining certain raw materials.

*raw materials
For the production of Xanthan gum (e415), sucrose obtained from sugar cane, Xanthomonas campestris, a microorganism, and potassium chloride, a salt, are generally used.
The production process is started by combining these raw materials appropriately.



PRODUCTION PROCESS OF XANTHAN GUM (e415):
The production process of Xanthan gum (e415) generally consists of these steps:
1) Sucrose and Xanthomonas campestris microorganism are mixed in a suitable environment.
2) The fermentation process begins and the microorganism produces Xanthan gum (e415) using sucrose.
3) Product stabilization is achieved by adding potassium chloride.

After the production process, Xanthan gum (e415) is subjected to various processes to obtain the product with the desired consistency and quality.
In this way, Xanthan gum (e415), which finds wide use in the food industry, is preferred to protect and improve the structure of many products as desired.



SOURCE OF XANTHAN GUM (e415):
Xanthan gum (e415) is used as a binder, emulsion and various skin healing agent and emulsifying surfactant.
The detailed use of Xanthan gum (e415) is also very effective, especially in providing freezing and melting stability.



PROPERTIES OF XANTHAN GUM (e415):
Xanthan gum (e415) made of natural sugar based polymers, the wanthan gum has many properties:
*Xanthan gum (e415) increases the viscosity of cold/hot liquid and pasty preparations (soups, creams, ice creams, nappages, coulis, syrups)
*Xanthan gum (e415) is used as a stabilizing and emulsifying agent, particularly in emulsified sauces (salad dressing, béarnaise, mayonnaise, marinades, vinaigrettes, hot sauces...)
*Xanthan gum (e415) increases the moist of bread and brioche
*Xanthan gum (e415) is used in dietetic pastries as a texturing agent.



WHAT DOES XANTHAN GUM (e415) DO AND HOW DO ı USE XANTHAN GUM (e415)?
Xanthan gum (e415) is a thickening and suspending agent that is heat stable, wth good tolerance for strongly acidic and basic solutions.
Viscosity of Xanthan gum (e415) remains stable over wide temperature range.
These propertities make Xanthan gum (e415) an ideal emulsifier, it also has synegistic effects with other hydrocolloids especially Guar Gum.



HISTORY OF XANTHAN GUM (e415):
Xanthan gum (e415) was first discovered in 1953 by a group of scientists working at Cornell University in the United States.
These scientists discovered that Xanthan gum (e415), a polysaccharide produced by the bacterium Xanthomonas campestris by fermenting sugars, could be used as a potential food additive.

Xanthan gum (e415) was first used in the food industry in the 1960s.
Xanthan gum (e415) was used to improve the consistency and texture of products such as yogurt, sauces and soups.
Xanthan gum (e415) quickly gained popularity and is widely used in many food products today.

Xanthan gum (e415) began to be used in the cosmetic industry in the 1970s.
Xanthan gum (e415) was used to improve the consistency and texture of products such as moisturizers, creams and lotions.

Xanthan gum (e415) is widely used in cosmetic products today.
Xanthan gum (e415) began to be used in industrial products in the 1980s.

Xanthan gum (e415) was used to improve the consistency and texture of products such as paints, inks and adhesives. Xanthan gum (e415) is widely used in industrial products today.
Xanthan gum (e415) is an important additive widely used today in food, cosmetics and industrial products.

Important dates regarding the history of Xanthan gum (e415):
*1953: Xanthan gum (e415) was discovered at Cornell University.
*1960s: Xanthan gum (e415) began to be used in the food industry.
*1970s: Xanthan gum (e415) began to be used in the cosmetic industry.
*1980s: Xanthan gum (e415) began to be used in industrial products.



GENERAL CHARACTERISTICS OF XANTHAN GUM (e415):
Xanthan gum (e415) is produced by obtaining xanthan, a natural polysaccharide, through fermentation.
Xanthan gum (e415) has the ability to form a gel by creating high viscosity when mixed with water.
Xanthan gum (e415) is soluble and stable at low temperature.

Xanthan gum (e415) is used in the food industry for various functions such as gel formation, emulsion stabilization and rheology control.
Xanthan gum (e415) is an additive generally used in many different products in the food processing industry.
Xanthan gum (e415) has important functions such as giving the products the desired texture, increasing stability and controlling rheology.



SHEAR THINNING OF XANTHAN GUM (e415):
The viscosity of Xanthan gum (e415) solutions decreases with higher shear rates.
This is called shear thinning or pseudoplasticity.
This means that a product subjected to shear, whether from mixing, shaking or chewing, will thin.

When the shear forces are removed, the food will thicken again.
In salad dressing, the addition of Xanthan gum (e415) makes it thick enough at rest in the bottle to keep the mixture fairly homogeneous, but the shear forces generated by shaking and pouring thins it, so it can be easily poured.

When it exits the bottle, the shear forces are removed and Xanthan gum (e415) thickens again, so it clings to the salad.
The rheology of xanthan aqua solutions become visco-elastic at higher concentrations of Xanthan gum (e415) in water.



CONCENTRATIONS USED OF XANTHAN GUM (e415):
The greater the concentration of Xanthan gum (e415) in a liquid, the thicker the liquid will become.
An emulsion can be formed with as little as 0.1% (by weight).
Increasing the concentration of gum gives a thicker, more stable emulsion up to 1% Xanthan gum (e415).
A teaspoon of Xanthan gum (e415) weighs about 2.5 grams and brings one cup (250 ml) of water to a 1% concentration.

To make a foam, 0.2–0.8% Xanthan gum (e415) is typically used.
Larger amounts result in larger bubbles and denser foam.
Egg white powder (0.2–2.0%) with 0.1–0.4% Xanthan gum (e415) yields bubbles similar to soap bubbles.



PREPARATION OF XANTHAN GUM (e415):
Xanthan gum (e415) is produced by the fermentation of glucose and sucrose.
The medium is well-aerated and stirred, and the xanthan polymer is produced extracellularly into the medium.

After one to four days, the polymer is precipitated from the medium by the addition of isopropyl alcohol, and the precipitate is dried and milled to give a powder that is readily soluble in water or brine.
Xanthan gum (e415) is composed of pentasaccharide repeat units, comprising glucose, mannose, and glucuronic acid in the molar ratio 2:2:1.

A strain of X. campestris that will grow on lactose has been developed – which allows it to be used to process whey, a waste product of cheese production.
This can produce 30 g/L of Xanthan gum (e415) for every 40 g/L of whey powder.
Whey-derived Xanthan gum (e415) is commonly used in many commercial products, such as shampoos and salad dressings.



WHAT IS THE SOURCE OF XANTHAN GUM (e415)?
Xanthan gum (e415) is considered natural.
Xanthan gum (e415) is produced through fermentation by the bacterium Xanthomonas campestris.
While the production process involves microbial fermentation, Xanthan gum (e415) is not synthesized from petrochemicals or other artificial sources, categorizing it as a natural thickening and stabilizing agent in the food industry.
As Xanthan gum (e415) is derived from the fermentation of plant based materials like glucose and sucrose, it is considered vegan and vegetarian.



ORIGIN OF XANTHAN GUM (e415):
Xanthan gum (e415) is a natural polysaccharide, produced by the bacterium Xanthomonas campestris from sugar and molasses.



FUNCTION AND CHARACTERISTICS OF XANTHAN GUM (e415):
*Thickening agent,
*stabiliser
*emulsifier.



HISTORY OF XANTHAN GUM (e415):
Xanthan gum (e415) was discovered by Allene Rosalind Jeanes and her research team at the United States Department of Agriculture, and brought into commercial production by CP Kelco under the trade name Kelzan in the early 1960s.
Xanthan gum (e415) was approved for use in foods in 1968 and is accepted as a safe food additive in the US, Canada, European countries, and many other countries, with E number E415, and CAS number 11138-66-2.



HOW TO USE OF XANTHAN GUM (e415):
Xanthan gum (e415) can produce a large increase in the viscosity of a liquid by adding a small amount (usually around 1%), however, in most applications, it is used at 0.5% or even as low as 0.05%



PACKAGING OF XANTHAN GUM (e415):
Dried Xanthan gum (e415) is packaged and made ready for use.
Xanthan gum (e415) production is usually carried out in large-scale tanks.
A nutrient medium containing sugar, nitrogen source, potassium phosphate and other trace elements is added to the tanks.
Then, Xanthomonas campestris bacterial culture is added to the tanks and left to ferment under aerobic conditions.
After fermentation is complete, Xanthan gum (e415) is isolated from the medium and dried.



PRODUCTION OF XANTHAN GUM (e415):
Xanthan gum (e415) is a polysaccharide produced by the bacteria Xanthomonas campestris by fermenting sugars.
Xanthan gum (e415) production consists of the following basic steps:


*Preparation of growth medium:
For the production of Xanthan gum (e415), a growth medium is prepared containing sugar (glucose, sucrose, fructose, etc.), nitrogen source (ammonium nitrate, ammonia, etc.), potassium phosphate and other trace elements.


*Preparation of bacterial culture:
Xanthomonas campestris bacteria is grown in a sterile environment.


*Fermentation:
Bacterial culture is added to the growth medium and allowed to ferment under aerobic conditions.
Fermentation time varies depending on the bacterial strain used for Xanthan gum (e415) production and the composition of the nutrient medium.



ISOLATION OF XANTHAN GUM (e415):
After fermentation is completed, Xanthan gum (e415) is isolated from the medium.
This process can be carried out by methods such as centrifugation, filtration or precipitation.

*Drying of Xanthan gum (e415):
The isolated Xanthan gum (e415) is dried.
This process can be carried out by methods such as vacuum drying, hot air drying or spray drying.



PHYSICAL and CHEMICAL PROPERTIES of XANTHAN GUM (e415):
Form: Powder
Appearance: white or cream-color and free-flowing powder
Viscosity: 1200 - 1600 mpa.s
Assay(on dry basis): 91.0 - 108.0%
Loss on drying(105o­C, 2hr): 6.0 - 12.0%
V1 : V2: 1.02 - 1.45
Pyruvic Acid: ≥ 1.5%
PH of 1% solution in water: 6.0 - 8.0
Heavy metals(as Pb): ≤ 20 mg/kg
Physical state: solid
Color: No data available
Odor: No data available

Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available

Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Chemical Formula: C 35 H 49 O 29
Molar Mass: 33.748 g mol −1



FIRST AID MEASURES of XANTHAN GUM (e415):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of XANTHAN GUM (e415):
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal



FIRE FIGHTING MEASURES of XANTHAN GUM (e415):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.
-Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of XANTHAN GUM (e415):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of XANTHAN GUM (e415):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.
hygroscopic
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of XANTHAN GUM (e415):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available


XANTHAN GUM 60 MESH
Synonyms: xylosic alcohol;XYLITOL CRYSTALLINE;XYLITOL, FOR BIOTECHNOLOGICAL PURPOSES;XYLITOL, 1GM, NEAT;Xylitol 1 M Solution;XYLITOL BIOSYNTH;XYLITOL, WHO 98.5-101.0%;XYLITOL, USP GRADE CAS: 87-99-0
XANTHAN GUM E415
XANTHAN GUM E415 is a substance that is used in food to obtain a higher degree of viscosity.
XANTHAN GUM E415 is also sometimes referred to as 'slow-liquidity'.
XANTHAN GUM E415 is of vegetable origin


CAS NUMBER: 11138-66-2

EC NUMBER: 266-357-1

MOLECULAR FORMULA: C8H14Cl2N2O2

MOLECULAR WEIGHT: 241.11

IUPAC NAME: 2-(2,4-diaminophenoxy)ethanol;dihydrochloride


XANTHAN GUM E415 is made from sugar and molasses.
XANTHAN GUM E415 is a nutritious sweetener which is a by-product of sugar production.

XANTHAN GUM E415 is used not only as a thickener but also as a stabiliser, emulsifier and gluten substitute.
XANTHAN GUM E415 is a very strong product that gives an obvious result even in small quantities.

XANTHAN GUM E415 is also assigned an e-number: E-415.
XANTHAN GUM E415 is a polysaccharide with many industrial uses, including as a common food additive.

XANTHAN GUM E415 is an effective thickening agent, emulsifier, and stabilizer that prevents ingredients from separating.
XANTHAN GUM E415 can be produced from simple sugars using a fermentation process
XANTHAN GUM E415 derives its name from the species of bacteria used, Xanthomonas campestris.

USES:
XANTHAN GUM E415 is commonly used in salad dressings and sauces in foods.
XANTHAN GUM E415 helps to prevent oil separation by stabilizing the emulsion, although it is not an emulsifier.

XANTHAN GUM E415 also helps suspend solid particles, such as spices.
XANTHAN GUM E415 helps create the desired texture in many ice creams.

Toothpaste often contains XANTHAN GUM E415 as a binder to keep the product uniform.
XANTHAN GUM E415 also helps thicken commercial egg substitutes made from egg whites, to replace the fat and emulsifiers found in yolks.

XANTHAN GUM E415 is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages at typical use levels.
In gluten-free baking, XANTHAN GUM E415 is used to give the dough or batter the stickiness that would otherwise be achieved with gluten.
In most foods XANTHAN GUM E415 is used at concentrations of 0.5% or less.

XANTHAN GUM E415 is used in a wide range of food products, such as sauces, dressings, meat and poultry products, bakery products, confectionery products, beverages, dairy products, and others.
In the oil industry, XANTHAN GUM E415 is used in large quantities to thicken drilling mud.

XANTHAN GUM E415 provides great "low end" rheology.
When circulation stops, the solids remain suspended in the drilling fluid.

XANTHAN GUM E415 has been added to concrete poured underwater, to increase its viscosity and prevent washout.
In cosmetics, XANTHAN GUM E415 is used to prepare water gels.
XANTHAN GUM E415 is also used in oil-in-water emulsions to enhance droplet coalescence.

XANTHAN GUM E415 is a high-molecular-weight extracellular polysaccharide
XANTHAN GUM E415 is widely used as a thickener

XANTHAN GUM E415 is used as an emulsifier and stabilizer in food with the European food additive number E415.
XANTHAN GUM E415 is different from other polysaccharide gums (same with gellan gum) as made from bacterial fermentation while others are extracted from or parts of a plant.

How is XANTHAN GUM E415 made?
Commercial XANTHAN GUM E415 is produced by fermentation of a carbohydrate source (mainly from corn starch) with strains of Xanthomonas campestris (a naturally occurring bacterium can be found on the leaf surfaces of green vegetables), then purified with ethanol or isopropanol.
The final product is manufactured to a salt (sodium, potassium or calcium).


Thickening with XANTHAN GUM E415 is commonly found in the following food products:
-Baked goods
-Dressings, frozen desserts
-Confections
-Cake and dessert mixes
-Dairy products
-Ice cream
-Pudding and gelatin mixes
-Jams and jellies
-Sauces & Seasonings
-salad dressings
-Meat & Egg Products


XANTHAN GUM E415 can be used in bakery (e.g. bread, cookies, biscuits, muffins, cakes) mainly for the following purposes:
XANTHAN GUM E415 can also be used as a substitute for eggs to reduce the usage of egg white but without affecting the soft taste and appearance.

Adding XANTHAN GUM E415 to the bread spread can prevent the spread of dehydration caused by the water absorption from bread.
XANTHAN GUM E415 can also be used in gluten free baking to replace the function of gluten to bind flour together which does good to people who have celiac disease.

XANTHAN GUM E415 can also be used as a water-binding agent and texture modifier in sausage and brine-injected ham to increase water holding capacity, impart a smooth and elastic
XANTHAN GUM E415 additive is a biopolymer with viscous, flexible, solidifying properties that plays an important role in gum application industries

XANTHAN GUM E415 Powder (E415) is a natural polysaccharide, cold water soluble product made from the fermentation of carbohydrates.
XANTHAN GUM E415 is used as a thickener and emulsifier (rheology modifier) in food products.

XANTHAN GUM E415 is a thickening and suspending agent that is heat stable, wth good tolerance for strongly acidic and basic solutions.
XANTHAN GUM E415 is a food additive used as a thickener or stabilizer

XANTHAN GUM E415 is soluble in water giving a highly viscous solution
XANTHAN GUM E415 is practically insoluble in organic solvents.

XANTHAN GUM E415 is a long chain polysaccharide, which is made by mixing fermented sugars (glucose, mannose, and glucuronic acid) with a certain kind of bacteria. It is mainly used to thicken and stabilize emulsions, foams, and suspensions.
XANTHAN GUM E415 is widely used as a food additive to control the rheological properties of a wide range of food products. In manufacturing, xanthan gum is used as a thickening and stabilizing agent in toothpastes and medicines.

XANTHAN GUM E415 is used to make medicine for lowering blood sugar and total cholesterol in people with diabetes.
XANTHAN GUM E415 is used as a laxative.
XANTHAN GUM E415 is sometimes used as a saliva substitute in people with dry mouth

XANTHAN GUM E415 occurs as a cream- or white-colored, odorless, freeflowing, fine powder.
XANTHAN GUM E415 is a gum obtained by microbial fermentation from the xanthomonas campestris organism.

XANTHAN GUM E415 is very stable to viscosity change over varying temperatures, ph, and salt concentrations.
XANTHAN GUM E415 is also very pseudoplastic which results in a decrease in viscosity with increasing shear.

XANTHAN GUM E415 reacts synergistically with guar gum and tara gum to provide an increase in viscosity and with carob gum to provide an increase in viscosity or gel formation.
XANTHAN GUM E415 is used in salad dressings, sauces, desserts, baked goods, and beverages at 0.05–0.50%.

XANTHAN GUM E415 is used as stabilizer and thickening agent in foods, pharmaceuticals, and cosmetics
XANTHAN GUM E415 is used for rheology control in water-based systems.
XANTHAN GUM E415 is used in oil and gas drilling and completion fluids.


PHYSICAL PROPERTIES:

-Molecular Weight: 241.11

-Exact Mass: 240.0432331

-Monoisotopic Mass: 240.0432331

-Topological Polar Surface Area: 81.5 Ų

-Physical Description: Light grey to light pink solid

-Color: Off-White to Pale Yellow

-Form: Solid

-Melting Point: 64.43 °C

-Storage Temperature: Hygroscopic, -20°C Freezer, Under inert atmosphere

-Solubility: Soluble in water giving a highly viscous solution, practically insoluble in organic solvents.


XANTHAN GUM E415 serves as a texturizer, carrier agent, and gelling agent in cosmetic preparations.
XANTHAN GUM E415 also stabilizes and thickens formulations.

XANTHAN GUM E415 is produced through a fermentation of carbohydrate and Xanthomonas campestris.
As xanthan is a polysaccharide used in many applications such as a food additive, enzyme substrate or rheology modifier

XANTHAN GUM E415 is useful to have a xanthan standard with a clearly defined narrow molecular weight distribution.
XANTHAN GUM E415 is produced by fermentation from Xanthomonas campestris.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 5

-Hydrogen Bond Acceptor Coun: 4

-Rotatable Bond Count: 3

-Heavy Atom Count: 14

-Formal Charge: 0

-Complexity: 132

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 3

-Compound Is Canonicalized: Yes

-Chemical Classes: Nitrogen Compounds -> Other Aromatics (Nitrogen)


XANTHAN GUM E415 is a substance that acts as an emulsifier, stabiliser, thickener, filler and binder.
XANTHAN GUM E415 is a fermentation gum.
Chemically XANTHAN GUM E415 is a high molecular weight polysaccharide obtained by aerobic fermentation of glucose in pure culture at ph = 6,0-7,5 and 28-30o C by the bacterium Xantomonas Campestris.

In addition to food, XANTHAN GUM E415 can also be used in:
– Personal care products: XANTHAN GUM E415 is also found in many personal care and beauty products.
XANTHAN GUM E415 allows these products to be thick, yet still flow easily from their containers.
XANTHAN GUM E415 also allows solid particles to suspend in liquids.
The following are some common products that contain xanthan gum: Toothpaste, Creams, Lotions, Shampoo.

– Industrial products: Xanthan gum is used in many industrial products because of its ability to withstand different temperatures and pH levels, clinging to surfaces and thickening liquids while maintaining good flow.

– Common industrial products containing xanthan gum include: fungicides, herbicides and insecticides, earthenware, mortar, toilet bowl, paints, fluids used in oil drilling, adhesives e.g. wallpaper glue.

XANTHAN GUM E415 is a high molecular weight polysaccharide produced by pure culture fermentation of a carbohydrate with strains of Xanthomonas campestris, purification by recovery with ethanol or 2-propanol, drying and grinding.
XANTHAN GUM E415 contains D-glucose and D-mannose as the dominant hexose units, together with D-glucuronic acid and pyruvic acid and is prepared as sodium, potassium or calcium salts.

XANTHAN GUM E415's solutions are neutral.
XANTHAN GUM E415 is a good thickening agent, replacing starch in some cases.

XANTHAN GUM E415 can also replace starch in some canned products, as it is the substance that allows easier heat exchange.
XANTHAN GUM E415 protects food from possible degradation caused by high temperatures in processing.
XANTHAN GUM E415 is a natural polysaccharide used in the food industry as an emulsifier and stabilizer as a food additive E415

XANTHAN GUM E415 is made from sugar and molasses.
XANTHAN GUM E415 is used not only as a thickener but also as a stabiliser, emulsifier and gluten substitute.
XANTHAN GUM E415 is commonly used in salad dressings and sauces in foods.

XANTHAN GUM E415 also helps suspend solid particles, such as spices.
XANTHAN GUM E415 is also a preferred method of thickening liquids for those with swallowing disorders, since it does not change the color or flavor of foods or beverages at typical use levels.

XANTHAN GUM E415 is also used in oil-in-water emulsions to enhance droplet coalescence.
XANTHAN GUM E415 is a high-molecular-weight extracellular polysaccharide

XANTHAN GUM E415 is widely used as a thickener
XANTHAN GUM E415 is used as a thickener and emulsifier (rheology modifier) in food products.
XANTHAN GUM E415 is a food additive used as a thickener or stabilizer

XANTHAN GUM E415 is soluble in water giving a highly viscous solution
XANTHAN GUM E415 is used as a laxative.

XANTHAN GUM E415 is used as stabilizer and thickening agent in foods, pharmaceuticals, and cosmetics
XANTHAN GUM E415 is used for rheology control in water-based systems.
XANTHAN GUM E415 is used in oil and gas drilling and completion fluids.


SYNONYMS:

66422-95-5
2-(2,4-DIAMINOPHENOXY)ETHANOL DIHYDROCHLORIDE
11138-66-2
2,4-Diaminophenoxyethanol HCl
2,4-Diaminophenoxyethanol dihydrochloride
Ethanol, 2-(2,4-diaminophenoxy)-, dihydrochloride
2,4-Diaminophenoxyethanol 2HCl
2-(2,4-Diaminophenoxy)ethanol hydrochloride
2-(2,4-diaminophenoxy)ethanol;dihydrochloride
2-(2,4-Diaminophenoxy)ethanol DiHCl
Ethanol, 2-(2,4-diaminophenoxy)-, hydrochloride (1:2)
4-(2-HYDROXYETHOXY)-1,3-PHENYLENEDIAMINE DIHYDROCHLORIDE
EINECS 266-357-1
70643-19-5
EC 266-357-1
AC-8295
CS-W012797
MB00378
YX29708
2, 4-DIAMINOPHENOXYETHANOL 2HCL
2,4-diamino-phenoxy-ethanol Hydrochloride
AS-12701
FT-0602826
FT-0626844
2,4-DIAMINOPHENOXYETHANOL HCL
A835461
2-(2,4-DIAMINOPHENOXY)ETHANOLDIHYDROCHLORIDE
W-104750
Q27295039
2-(2,4-DIAMINOPHENOXY)ETHANOL DIHYDROCHLORIDE
XANTHAN
GUM XANTHAN
Xanthan Gum powder
2,4-Diaminophenoxyethanol dihydrochloride
Ethanol, 2-(2,4-diaminophenoxy)-, dihydrochloride
2,4-Diaminophenoxyethanol 2HCl
2-(2,4-Diaminophenoxy)ethanol hydrochloride
2-(2,4-diaminophenoxy)ethanol;dihydrochloride
2-(2,4-Diaminophenoxy)ethanol DiHCl
Ethanol, 2-(2,4-diaminophenoxy)-, hydrochloride (1:2)
4-(2-HYDROXYETHOXY)-1,3-PHENYLENEDIAMINE DIHYDROCHLORIDE
EINECS 266-357-1
GLUCOMANNAN MAYO
Xanthane gum
Konjac extract
XANTHAM
Tarazine
Keltrol F
Xanthan g
GALACTOMANNANE
GLUCOMANNAN
GLUCOMANNAN MAYO
GUM XANTHAN
KONJAC GLUCOMANNAN
RHODOPOL 23
XANTEMPO(TM)
XANTHAN
XANTHAN GUM
xanthangumfromxanthomonascampestris
XANTHAM
Xanthan Gum Xanthomonas campestris
xanthan gum Xc
Xanthan gum pharma
XANTHAN GUM FOR FOOD & PHARMACEUTICAL APPLICATION
XanthanGumPure
XANTHANGUM,FCC
XANTHANGUM,NF
XANTHATEGUM
Xanthan Gummi

XANTHAN GUM E415

Xanthan gum E415 is a natural food thickener, stabilizer, and emulsifier derived from a bacterial fermentation process.
Xanthan gum E415 is a soluble fiber produced by the bacterium Xanthomonas campestris, and has a high molecular weight with a molecular structure similar to that of cellulose.
Xanthan gum E415 is commonly used in food and beverage applications as a thickener, stabilizer, and emulsifier, as well as in the production of personal care and household products.

CAS Number: 11138-66-2



APPLICATIONS


Xanthan gum E415 is commonly used as a thickening agent in food products such as salad dressings, sauces, and gravies.
Xanthan gum E415 is also used in bakery products to improve dough stability and texture.
In dairy products, Xanthan gum E415 is used to prevent syneresis and to improve mouthfeel.

Xanthan gum E415 is used in the production of pet foods to improve their texture and consistency.
Xanthan gum E415 is used in the pharmaceutical industry as a binder and disintegrant in tablet formulations.

Xanthan gum E415 is used in personal care products such as toothpaste, shampoo, and lotions as a thickener and stabilizer.
Xanthan gum E415 is used in oil drilling operations to increase the viscosity of drilling fluids.

Xanthan gum E415 is used in the production of paper to improve the retention of fillers and other additives.
In textile printing, Xanthan gum E415 is used as a thickener and stabilizer in printing pastes.

Xanthan gum E415 is used as a thickener in paints and coatings to improve their flow and stability.
Xanthan gum E415 is used in the production of adhesives and sealants as a thickener and binder.

In the construction industry, Xanthan gum E415 is used as a thickener and stabilizer in cement-based products.
Xanthan gum E415 is used in the production of explosives as a thickener and stabilizer.

Xanthan gum E415 is used in the production of insecticides and herbicides as a thickener and dispersant.
Xanthan gum E415 is used in the cosmetics industry as a thickener and stabilizer in lotions and creams.
Xanthan gum E415 is used in the production of detergents and cleaning products as a thickener and stabilizer.

Xanthan gum E415 is used in the printing industry as a thickener and binder in ink formulations.
Xanthan gum E415 is used in the production of rubber products as a filler and stabilizer.

In the petroleum industry, Xanthan gum E415 is used as a thickener and stabilizer in drilling fluids and fracturing fluids.
Xanthan gum E415 is used in the production of ceramics to improve their strength and reduce cracking.

Xanthan gum E415 is used in the production of textiles to improve their dye absorption and to prevent shrinkage.
Xanthan gum E415 is used in the production of detergents and cleaning products as a thickener and stabilizer.
Xanthan gum E415 is used in the production of water-based paints and coatings to improve their flow and stability.

Xanthan gum E415 is used in the production of plastics to improve their viscosity and processing characteristics.
Xanthan gum E415 is used in the production of explosives as a thickener and stabilizer.


Xanthan gum E415 has a wide range of applications in various industries due to its excellent rheological properties, stability, and compatibility with other ingredients.
Some of its applications are:


Food industry:

Xanthan gum E415 is commonly used as a thickening agent, stabilizer, and emulsifier in various food products such as sauces, dressings, dairy products, baked goods, and beverages.


Oil and gas industry:

Xanthan gum E415 is used as a drilling mud additive to provide viscosity control and suspension of solids in the drilling fluid.


Personal care industry:

Xanthan gum E415 is used in various personal care products such as shampoos, conditioners, lotions, and creams as a thickener and stabilizer.


Pharmaceutical industry:

Xanthan gum E415 is used in various pharmaceutical formulations as a suspending agent and thickener.


Agriculture:

Xanthan gum E415 is used as a soil stabilizer, seed coating agent, and plant growth regulator.


Textile industry:

Xanthan gum E415 is used in textile printing as a thickener for printing pastes.


Paint and coatings industry:

Xanthan gum E415 is used as a thickener and stabilizer in paint and coatings formulations.


Adhesives industry:

Xanthan gum E415 is used as a thickener and rheology modifier in adhesive formulations.


Paper industry:

Xanthan gum E415 is used as a retention aid and drainage aid in papermaking.


Cosmetics industry:

Xanthan gum E415 is used in cosmetics products as a thickener and emulsifier.


Water treatment:

Xanthan gum E415 is used in water treatment processes as a flocculant and clarifier.


Detergent industry:

Xanthan gum E415 is used as a thickener and stabilizer in detergent formulations.


Mining industry:

Xanthan gum E415 is used in the mining industry as a thickener and rheology modifier in flotation slurries.


Construction industry:

Xanthan gum E415 is used as a thickener and stabilizer in construction materials such as mortars and grouts.


Ceramic industry:

Xanthan gum E415 is used as a binder and rheology modifier in ceramic formulations.


Rubber industry:

Xanthan gum E415 is used as a thickener and stabilizer in rubber formulations.


Soil erosion control:

Xanthan gum E415 is used as a soil stabilizer and erosion control agent.


Fuel industry:

Xanthan gum E415 is used as a thickener and stabilizer in fuel formulations.


Water-based drilling fluids:

Xanthan gum E415 is used as a viscosifier and rheology modifier in water-based drilling fluids.


Metalworking industry:

Xanthan gum E415 is used as a lubricant and rheology modifier in metalworking fluids.


Explosives industry:

Xanthan gum E415 is used as a thickener and stabilizer in explosive formulations.


Plastics industry:

Xanthan gum E415 is used as a rheology modifier in plastic formulations.


Biotechnology:

Xanthan gum E415 is used as a substrate in various biotechnology applications such as fermentation and cell culture.


Waste management:

Xanthan gum E415 is used as a flocculant and clarifier in waste management processes.


Environmental remediation:

Xanthan gum E415 is used as a thickener and stabilizer in environmental remediation processes.


Xanthan gum E415 is used as a thickening agent in food products such as salad dressings and sauces.
Xanthan gum E415 helps improve the texture of dairy products, such as ice cream and yogurt.
Xanthan gum E415 is often used as a binding agent in gluten-free baking.

Xanthan gum E415 is used as a stabilizer in bottled salad dressings, preventing separation of ingredients.
Xanthan gum E415 is used in the production of gluten-free beer to improve the texture and mouthfeel.

Xanthan gum E415 is used in the petroleum industry to help thicken drilling muds.
Xanthan gum E415 helps control the rheology of fluids in the oil and gas industry.

Xanthan gum E415 is used in the production of personal care and cosmetic products, such as shampoos and lotions.
Xanthan gum E415 helps improve the texture of toothpaste and other oral care products.

Xanthan gum E415 is used in the production of paper products to improve their strength and texture.
Xanthan gum E415 is used as a binder in the manufacture of tablets and pills in the pharmaceutical industry.

Xanthan gum E415 is used in the production of textile and dye products as a thickener.
Xanthan gum E415 is used in the production of paint and coatings to improve their stability and texture.
Xanthan gum E415 helps to improve the freeze-thaw stability of food products.

Xanthan gum E415 is used in the production of animal feed to improve the texture and consistency.
Xanthan gum E415 is used in the production of detergents and cleaning products as a thickener and stabilizer.

Xanthan gum E415 is used in the production of ceramics to help control the rheology of the clay.
Xanthan gum E415 is used in the production of adhesives to improve their bonding properties.

Xanthan gum E415 helps to improve the stability of emulsions, such as salad dressings and mayonnaise.
Xanthan gum E415 is used in the production of fruit juices and smoothies to improve their texture and mouthfeel.

Xanthan gum E415 is used as a suspending agent in the production of pharmaceutical suspensions.
Xanthan gum E415 is used in the production of artificial tears to improve their viscosity.

Xanthan gum E415 helps to improve the freeze-thaw stability of personal care products.
Xanthan gum E415 is used in the production of animal feed to improve the digestibility of nutrients.
Xanthan gum E415 is used in the production of oil-based drilling fluids to help improve their stability and rheology.

Xanthan gum E415 is commonly used in the food industry to improve texture and stability in a variety of products, including dressings, sauces, and baked goods.
Xanthan gum E415 is frequently used in gluten-free baking to help simulate the elasticity and texture of gluten-containing products.

In the pharmaceutical industry, Xanthan gum E415 is used as a binder and disintegrant in tablet formulations.
Xanthan gum E415 is used in the oil and gas industry as a thickening agent in drilling fluids to improve wellbore stability.

Xanthan gum E415 is also used in the cosmetic industry as a thickening agent and stabilizer in a variety of products, including lotions and creams.
Xanthan gum E415 is often added to toothpaste to improve its consistency and make it easier to apply.
In the textile industry, Xanthan gum E415 is used as a sizing agent to help prevent yarn breakage during weaving.

Xanthan gum E415 is also used as a stabilizer in latex paint formulations.
Xanthan gum E415 is used in the production of fermented dairy products, such as yogurt, to improve texture and prevent separation.

Xanthan gum E415 is used in the production of ice cream to improve texture and prevent the formation of ice crystals.
Xanthan gum E415 is used in the production of pet food to improve texture and help prevent separation of ingredients.

Xanthan gum E415 is used in the paper industry as a coating agent to improve the printability and appearance of paper.
Xanthan gum E415 is used in the construction industry as a thickening agent in cement and mortar formulations to improve workability.
Xanthan gum E415 is used in the water treatment industry as a flocculant to help remove suspended solids from wastewater.

In the mining industry, Xanthan gum E415 is used as a thickener and stabilizer in mineral processing applications.
Xanthan gum E415 is used in the production of adhesives to improve their viscosity and stability.

Xanthan gum E415 is used in the production of detergents as a thickener and stabilizer.
Xanthan gum E415 is used in the production of pesticides as a thickener and dispersant.
Xanthan gum E415 is used in the production of personal care products, such as shampoos and body washes, as a thickener and stabilizer.

Xanthan gum E415 is used in the production of cleaning products, such as dishwashing detergent, as a thickener and stabilizer.
Xanthan gum E415 is used in the production of drilling muds in the mining industry to improve viscosity and reduce fluid loss.

Xanthan gum E415 is used in the production of paper coatings to improve print quality and reduce ink absorption.
Xanthan gum E415 is used in the production of ceramic slurries to improve rheology and stability.

Xanthan gum E415 is used in the production of synthetic latex to improve stability and reduce viscosity.
Xanthan gum E415 is used in the production of surfactants as a thickener and stabilizer.



DESCRIPTION


Xanthan gum E415 is a natural food thickener, stabilizer, and emulsifier derived from a bacterial fermentation process.
Xanthan gum E415 is a soluble fiber produced by the bacterium Xanthomonas campestris, and has a high molecular weight with a molecular structure similar to that of cellulose.
Xanthan gum E415 is commonly used in food and beverage applications as a thickener, stabilizer, and emulsifier, as well as in the production of personal care and household products.

Xanthan gum E415 is highly soluble in both cold and hot water and has a neutral taste and odor, making it ideal for use in a wide range of applications.
Xanthan gum E415 is also resistant to heat, acid, and shear, making it useful in high-temperature processing and in acidic or low-pH environments.

In food applications, Xanthan gum E415 is used in a variety of products including salad dressings, sauces, soups, bakery products, dairy products, and meat products.
Xanthan gum E415 is also used in gluten-free baking as a substitute for wheat flour.

Xanthan gum E415 is also used in personal care products such as shampoos, lotions, and toothpaste, as well as in household products such as cleaning solutions and laundry detergents.
Xanthan gum E415 is considered safe for consumption by regulatory agencies such as the FDA, and is often used as an alternative to other synthetic thickening agents in natural and organic products.
Xanthan gum E415 can be used in combination with other hydrocolloids such as guar gum or carrageenan to achieve specific textural or functional properties in food products.

Xanthan gum E415 is available in a variety of grades, including food grade, pharmaceutical grade, and industrial grade, each with different specifications and applications.
Xanthan gum E415 is also used in oil and gas drilling as a drilling fluid additive to improve viscosity and suspension properties.

The production of Xanthan gum E415 involves a fermentation process using a sugar source and the bacterium Xanthomonas campestris.
Xanthan gum E415 has been shown to have potential health benefits such as reducing blood sugar levels and cholesterol levels, and may have a prebiotic effect in the gut.

Xanthan gum E415 is commonly used in gluten-free food products to improve texture and maintain stability, as gluten is a common binder in traditional baked goods.
Xanthan gum E415 is often used in pet food and animal feed products as a thickener and stabilizer.

Xanthan gum E415 is also used in the production of paper and textiles as a thickening and sizing agent.
Xanthan gum E415 is generally recognized as safe (GRAS) by the FDA and has a low toxicity profile.

Xanthan gum E415 is also used in the production of biodegradable polymers and as a suspending agent in pharmaceuticals.
Xanthan gum E415 has been used in the preservation of cultural heritage artifacts, such as paper and parchment, as a consolidant and adhesive.

Xanthan gum E415 is resistant to microbial attack and can help extend the shelf life of food products.
Xanthan gum E415 has a low caloric value and is often used as a low-calorie substitute for other thickeners and stabilizers.
Xanthan gum E415 can be used in a variety of formulations, including liquids, gels, and powders, and can be used in both low- and high-viscosity applications.

Xanthan gum E415 is often used in cosmetics as a thickener and stabilizer to improve texture and stability.
Xanthan gum E415 can be used to thicken and stabilize aqueous solutions and suspensions, as well as oil-in-water emulsions.

Xanthan gum E415 is a natural thickener and stabilizer derived from bacteria.
Xanthan gum E415 has a white or cream-colored powder form.
Xanthan gum E415 is an anionic polysaccharide.

Xanthan gum E415 is soluble in both hot and cold water, making it versatile in many applications.
Xanthan gum E415 has a neutral taste and odor.

Xanthan gum E415 can be used in both food and non-food applications.
Xanthan gum E415 is commonly used in gluten-free baking as a substitute for gluten.
Xanthan gum E415 can also be found in many sauces, dressings, and condiments to thicken and stabilize them.

Xanthan gum E415 can improve the mouthfeel and texture of many products.
Xanthan gum E415 is often used in personal care and cosmetic products for its thickening and stabilizing properties.

Xanthan gum E415 is also used in the oil and gas industry for drilling fluids.
Xanthan gum E415 is highly resistant to temperature changes and can maintain its viscosity at both high and low temperatures.
Xanthan gum E415 is not fermentable by common intestinal bacteria.

Xanthan gum E415 has a long shelf life and can be stored at room temperature.
Xanthan gum E415 is approved for use in the European Union, United States, and many other countries.

Xanthan gum E415 can help prevent syneresis in frozen foods by stabilizing water.
Xanthan gum E415 can be used in low-fat or fat-free dairy products to mimic the texture of full-fat products.
Xanthan gum E415 is often used in pet food to improve texture and palatability.

Xanthan gum E415 can improve the yield and quality of certain meat products.
Xanthan gum E415 can be used in pharmaceuticals to improve the texture of tablets and capsules.

Xanthan gum E415 is often used in toothpaste and mouthwash for its thickening and stabilizing properties.
Xanthan gum E415 is commonly used in papermaking for its ability to improve paper strength and formation.

Xanthan gum E415 is an environmentally friendly alternative to synthetic thickeners and stabilizers.
Xanthan gum E415 is compatible with many other ingredients and can be used in combination with other thickeners and stabilizers.
Xanthan gum E415 is a versatile and widely used ingredient that can enhance the texture and stability of many products.



PROPERTIES


Appearance: Fine, white to cream colored powder
Odor: Odorless
Solubility: Soluble in cold or hot water, insoluble in organic solvents
pH: Stable between pH 1 and 13, with optimum stability between pH 3 and 9
Viscosity: High viscosity at low concentrations, shear-thinning behavior
Rheology: Pseudoplastic, thixotropic behavior
Molecular weight: Average molecular weight of approximately 2 million daltons
Thermal stability: Stable up to 80-85°C (176-185°F), with some degradation above that temperature
Chemical stability: Stable in the presence of most salts, acids, and bases
Compatibility: Compatible with most common food ingredients and additives
Hygroscopicity: Absorbs moisture from the air, with a tendency to clump and form lumps in high humidity conditions
Water holding capacity: High water-holding capacity, with the ability to form gels and retain moisture
Emulsification: Effective emulsifier, stabilizing oil-in-water emulsions
Foaming: Forms stable foams with good foam stability and high overrun
Freeze-thaw stability: Good freeze-thaw stability, with the ability to withstand multiple freeze-thaw cycles without loss of functionality
Shear stability: Resistant to shear forces, maintaining viscosity and other functional properties under high shear conditions
Microbial stability: Resistant to microbial growth and contamination
Toxicity: Non-toxic and safe for consumption
Allergenicity: Non-allergenic and gluten-free
Nutritional value: Low calorie, low fat, and high fiber content
Shelf life: Long shelf life, with stable functionality and quality over time
Production: Produced by fermentation of carbohydrates using the bacterium Xanthomonas campestris
Sustainability: Renewable, biodegradable, and environmentally friendly
Cost: Relatively low cost compared to other hydrocolloids and thickeners.



FIRST AID


In case of exposure to Xanthan gum E415, the following first aid measures are recommended:

Inhalation:

Move the affected person to fresh air and seek medical attention if breathing difficulties persist.


Skin contact:

Remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes.
Seek medical attention if irritation or redness develops.


Eye contact:

Rinse the affected eye with plenty of water for at least 15 minutes while holding the eyelids open.
Seek medical attention if irritation or pain persists.


Ingestion:

Do not induce vomiting.
Rinse the mouth with water and seek medical attention immediately.
It is important to note that Xanthan gum E415 is generally considered safe for consumption and poses a low risk of toxicity.

However, in rare cases, ingestion of large amounts of Xanthan gum E415 may cause gastrointestinal distress such as bloating, gas, and diarrhea.
If symptoms persist or worsen, medical attention should be sought.



HANDLING AND STORAGE


Xanthan gum E415 should be stored in a cool, dry place and protected from direct sunlight.
Xanthan gum E415 should be stored in airtight containers and away from sources of heat and ignition.

During handling, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat.
If Xanthan gum E415 is accidentally ingested, medical attention should be sought immediately, and the mouth should be rinsed with water.
In case of contact with skin or eyes, the affected area should be flushed with water for at least 15 minutes, and medical attention should be sought if irritation persists.

Spills or leaks should be cleaned up promptly using appropriate absorbents.
Xanthan gum E415 should be disposed of according to local regulations and in compliance with applicable environmental laws.
It should not be released into the environment, especially not into waterways or drains.



SYNONYMS


E415
Corn sugar gum
Xanthomonas campestris gum
XC polymer
Bacterial polysaccharide
Polysaccharide B-1459
Rheogel
Rhodigel
Kelzan
Keltrol
Rhamsan
Tixogel
Flocon
Santan
Xanthan rubber
Biopolymer Xanthan
Ziboxan
Xanthomonas polysaccharide
Natural gum
Kelzan
Keltrol
Rhodopol
Rhodicare
Tegogel
ActiCol
Altra-Gel
Aquaflow
Nutriose
Novasol
Nuvisan
OptiXan
Polysynthan
Polysax
Primafloc
Rhodion
Satiagel
Sinofi
Solvitar
Stabisol
Supercol
Thixcin
X-gum
Xanfibe
Xantural
XANTHAN GUM POLYSACCHARİDE

Xanthan gum polysaccharide is a polysaccharide, which is a type of large molecule composed of repeating sugar units.
Xanthan gum polysaccharide is produced through fermentation by the bacterium Xanthomonas campestris.
The chemical structure of xanthan gum consists of a backbone made up of repeating glucose, mannose, and glucuronic acid units, with side chains attached to some of the glucose units.

CAS Number: 11138-66-2
EC Number: 234-394-2



APPLICATIONS


Xanthan gum polysaccharide is widely used in the food industry as a thickener and stabilizer in products like sauces and dressings.
In gluten-free baking, Xanthan gum polysaccharide is a crucial ingredient, providing the necessary structure and elasticity.
Xanthan gum polysaccharide enhances the texture and mouthfeel of various dairy products, including ice creams and yogurts.
Salad dressings often contain Xanthan gum to prevent phase separation and improve suspension of ingredients.

Xanthan gum polysaccharide is utilized in the production of gluten-free bread and baked goods, contributing to their softness and volume.
Xanthan gum polysaccharide is added to beverages, such as fruit juices and smoothies, to prevent sedimentation and improve viscosity.

In the cosmetic industry, it is used in creams and lotions for its thickening and stabilizing properties.
Toothpaste formulations may include Xanthan gum polysaccharide to provide a desirable texture and prevent separation of ingredients.
Xanthan gum polysaccharide is used in pharmaceuticals as a suspending agent for oral suspensions and liquid medications.

Xanthan gum polysaccharide finds application in the petroleum industry for enhanced oil recovery, improving the viscosity of injected fluids.
Xanthan gum polysaccharide is utilized in the production of water-based paints and coatings to control rheology and prevent settling.

Xanthan gum polysaccharide is added to cleaning products to enhance their viscosity and cling to vertical surfaces.
Xanthan gum polysaccharide is used in the textile industry for sizing, providing a protective coating on fibers during the manufacturing process.
Xanthan gum polysaccharide is employed in agriculture to improve the adhesion and spreading of pesticides and herbicides.
Xanthan gum polysaccharide is a common ingredient in gluten-free pasta and noodle formulations, contributing to their texture and structure.

Xanthan gum polysaccharide is utilized in the production of pet food to improve the consistency and palatability of the products.
Xanthan gum polysaccharide is added to instant food products, such as soups and gravies, to achieve rapid thickening upon rehydration.
Xanthan gum polysaccharide is used in the creation of gel-based formulations in the pharmaceutical and personal care industries.

Xanthan gum polysaccharide is a key component in the preparation of hydrocolloid gels used in molecular gastronomy.
Xanthan gum is employed in the production of biodegradable films for food packaging.
Xanthan gum polysaccharide is used in the formulation of oral care products like mouthwash and dental gels for their thickening effects.
Xanthan gum polysaccharide is added to cosmetic emulsions to stabilize the oil-in-water or water-in-oil systems.

In the construction industry, it finds application in cementitious materials to improve workability and adhesion.
Xanthan gum polysaccharide is utilized in water treatment processes to enhance flocculation and settleability of suspended particles.
Xanthan gum polysaccharide is employed in the creation of lubricating fluids to improve their viscosity and stability in various industrial applications.

Xanthan gum polysaccharide is commonly used in the production of gluten-free pancake and waffle mixes to improve their batter consistency.
Xanthan gum polysaccharide finds application in the dairy industry for the stabilization of chocolate milk and flavored milk products.

In the production of canned pet food, Xanthan gum helps maintain a consistent texture and prevents separation of ingredients.
Xanthan gum polysaccharide is added to fruit fillings and pie fillings to enhance their viscosity and prevent syneresis.
Xanthan gum polysaccharide is utilized in the manufacturing of certain pharmaceutical tablets as a binder and disintegrant.

Xanthan gum polysaccharide is used in the creation of gel-based wound dressings and medical adhesives.
In the oil and gas industry, Xanthan gum is employed in drilling fluids to provide viscosity and suspend solids.
Xanthan gum polysaccharide is found in the formulation of hair care products, such as styling gels and mousses, for its thickening properties.

Xanthan gum polysaccharide is used in the production of plant-based meat substitutes to improve the texture and juiciness of the products.
Xanthan gum polysaccharide is added to instant coffee and other powdered beverages to enhance their solubility and mouthfeel.
In the pharmaceutical industry, it is used as a gelling agent in the preparation of oral and topical gels.

Xanthan gum polysaccharide is employed in the creation of gel-based fire retardants for use in textiles and materials.
Xanthan gum polysaccharide is used in the preparation of water-based drilling muds for tunneling and horizontal drilling applications.
Xanthan gum polysaccharide finds application in the stabilization of latex-based paints to prevent settling of pigments.

In the textile printing process, Xanthan gum is utilized to thicken and control the viscosity of printing pastes.
Xanthan gum polysaccharide is added to certain types of explosive formulations to improve their viscosity and handling characteristics.
Xanthan gum polysaccharide is used in the production of hydroseeding slurries to improve the suspension of seeds and fertilizers.

Xanthan gum polysaccharide is employed in the formulation of insecticides and herbicides to improve their adherence to plant surfaces.
In the creation of biodegradable hydraulic fluids, Xanthan gum serves as a thickening and stabilizing agent.

Xanthan gum polysaccharide is utilized in the preparation of gel-based food supplements and nutritional products.
Xanthan gum polysaccharide finds application in the stabilization of ready-to-drink protein shakes and nutritional beverages.
Xanthan gum polysaccharide is used in the production of certain medical-grade lubricating gels for surgical procedures.

In the ceramics industry, Xanthan gum polysaccharide is added to glazes and slurries to control their rheological properties.
Xanthan gum polysaccharide is employed in the production of printing inks to control viscosity and improve printability.
Xanthan gum polysaccharide is utilized in the creation of gel-based bait formulations for pest control applications.

Xanthan gum polysaccharide is used in the formulation of hydrocolloid-based wound dressings for controlled moisture management.
Xanthan gum polysaccharide finds application in the creation of gel-based air fresheners and odor-control products for home and industrial use.
In the production of gluten-free cookies and baked goods, Xanthan gum polysaccharide contributes to the desired texture and structure.
Xanthan gum polysaccharide is employed in the formulation of controlled-release drug delivery systems in pharmaceuticals.

Xanthan gum polysaccharide is utilized in the stabilization of fruit juices and nectars to prevent sedimentation and enhance mouthfeel.
Xanthan gum polysaccharide finds application in the preparation of gel-based veterinary pharmaceuticals for oral administration.

In the mining industry, Xanthan gum polysaccharide is used in ore flotation processes to improve the separation of minerals.
Xanthan gum polysaccharide is added to latex-based adhesive formulations to control viscosity and improve bond strength.
Xanthan gum polysaccharide is utilized in the production of gel-based electrolyte solutions for medical and sports hydration.
In the creation of gel-based airbrushing media for artists, Xanthan gum aids in pigment suspension and flow control.

Xanthan gum polysaccharide is employed in the stabilization of suspension fertilizers for agricultural applications.
Xanthan gum polysaccharide is used in the production of gel-based bait formulations for pest control applications.
Xanthan gum polysaccharide is added to certain types of inkjet printer inks to control viscosity and improve print quality.
In the textile printing industry, Xanthan gum is utilized to create controlled rheological properties in dye pastes.

Xanthan gum polysaccharide finds application in the formulation of gel-based wound healing ointments and topical treatments.
Xanthan gum polysaccharide is added to ceramic glazes to enhance suspension and improve application properties.
Xanthan gum polysaccharide is employed in the preparation of gel-based reagents for laboratory and diagnostic applications.

In the creation of gel-based fire extinguishing agents, Xanthan gum contributes to viscosity and adherence.
Xanthan gum polysaccharide is used in the stabilization of ink formulations for rollerball and gel pens.
Xanthan gum polysaccharide finds application in the formulation of gel-based veterinary pharmaceuticals for oral administration.

Xanthan gum polysaccharide is utilized in the production of gel-based lubricants for medical and personal use.
Xanthan gum polysaccharide is added to certain types of adhesives to control rheology and improve application properties.
In the creation of gel-based formulations for ultrasound imaging, Xanthan gum aids in consistency and dispersion.
Xanthan gum polysaccharide is employed in the formulation of gel-based concrete additives to improve workability and adhesion.
Xanthan gum polysaccharide is used in the stabilization of gel-based suspensions for magnetic resonance imaging (MRI) contrast agents.

Xanthan gum polysaccharide is utilized in the formulation of gel-based cosmetic masks for skincare applications.
Xanthan gum polysaccharide finds application in the creation of gel-based wound sealants and tissue adhesives for medical use.
In the paper and pulp industry, Xanthan gum polysaccharide is added to coating formulations to control viscosity and improve application properties.

Xanthan gum polysaccharide is employed in the stabilization of gel-based suspensions used in the casting of dental molds.
Xanthan gum polysaccharide is used in the creation of gel-based plant growth regulators for agricultural and horticultural purposes.
In the construction industry, it is added to cementitious materials to improve their workability and adhesion.

Xanthan gum polysaccharide finds application in the formulation of gel-based water-soluble films for packaging and dissolvable applications.
Xanthan gum polysaccharide is utilized in the stabilization of gel-based suspensions for ceramic slip casting.
Xanthan gum polysaccharide is employed in the formulation of gel-based drilling fluids for geotechnical and environmental drilling.

In the creation of gel-based pet care products, Xanthan gum contributes to texture and viscosity.
Xanthan gum polysaccharide is added to certain types of gel-based sunscreen formulations for its thickening and stabilizing effects.
Xanthan gum polysaccharide is used in the stabilization of gel-based insecticides and pest control products.
Xanthan gum polysaccharide finds application in the formulation of gel-based casting materials for crafting and mold-making.

Xanthan gum polysaccharide is employed in the preparation of gel-based encapsulation systems for controlled release in pharmaceuticals.
Xanthan gum polysaccharide is utilized in the stabilization of gel-based paints and coatings to prevent settling.
In the production of gel-based bioremediation agents, it contributes to suspension and dispersion.
Xanthan gum polysaccharide is added to gel-based soil amendments to improve water retention and nutrient delivery.

Xanthan gum polysaccharide is used in the formulation of gel-based adhesives for laminating and bonding applications.
Xanthan gum polysaccharide finds application in the creation of gel-based matrix materials for controlled drug delivery systems.

In the petroleum industry, Xanthan gum is employed in the formulation of gel-based drilling and completion fluids.
Xanthan gum polysaccharide is utilized in the stabilization of gel-based formulations for the encapsulation of fragrance microcapsules.
Xanthan gum polysaccharide is added to certain types of gel-based ink formulations for ballpoint and rollerball pens.

In the creation of gel-based foam stabilizers, it enhances foam consistency in various applications.
Xanthan gum polysaccharide is employed in the formulation of gel-based bath and shower products for texture and viscosity.
Xanthan gum polysaccharide is used in the stabilization of gel-based formulations for controlled-release fertilizers.

Xanthan gum polysaccharide is utilized in the formulation of gel-based air fresheners for controlled and prolonged release of fragrances.
Xanthan gum polysaccharide finds application in the creation of gel-based wound care products such as gels and dressings.
In the printing industry, Xanthan gum polysaccharide is added to inkjet inks to enhance stability, preventing clogging and improving print quality.

Xanthan gum polysaccharide is employed in the stabilization of gel-based formulations for encapsulating and delivering essential oils.
Xanthan gum polysaccharide is used in the formulation of gel-based veterinary pharmaceuticals for oral and topical administration.

In the manufacturing of gel-based contact lens solutions, it aids in viscosity control and lens lubrication.
Xanthan gum polysaccharide is added to gel-based concrete additives to improve workability, reduce segregation, and enhance adhesion.
Xanthan gum polysaccharide is utilized in the stabilization of gel-based suspensions for casting intricate and detailed molds in the art and craft industry.
Xanthan gum polysaccharide finds application in the formulation of gel-based wound irrigation solutions for medical procedures.

In the production of gel-based photographic emulsions, Xanthan gum is used as a thickening agent for better coating properties.
Xanthan gum polysaccharide is employed in the stabilization of gel-based suspensions for the casting of dental impressions and molds.
Xanthan gum polysaccharide is used in the formulation of gel-based artificial saliva for individuals with dry mouth conditions.

In the creation of gel-based fire retardants, it aids in controlling the viscosity and adhering to surfaces.
Xanthan gum polysaccharide is added to gel-based lubricating fluids for machinery and industrial equipment to improve viscosity and stability.
Xanthan gum polysaccharide is utilized in the stabilization of gel-based formulations for microencapsulation of vitamins and nutrients.
Xanthan gum polysaccharide finds application in the formulation of gel-based biopolymer films used for edible coatings on fruits and vegetables.

In the textile industry, the gum is added to gel-based sizing formulations to enhance adhesion and improve fiber protection.
Xanthan gum polysaccharide is used in the production of gel-based artificial sputum for respiratory therapy and medical research.
Xanthan gum polysaccharide is employed in the stabilization of gel-based formulations for controlled drug release in pharmaceuticals.

In the creation of gel-based flotation agents in mining, Xanthan gum aids in mineral separation processes.
Xanthan gum polysaccharide is added to gel-based liquid fertilizers for improved stability and nutrient delivery in agriculture.
Xanthan gum polysaccharide is utilized in the formulation of gel-based reagents for gel electrophoresis in molecular biology.
In the cosmetic industry, Xanthan gum is used in gel-based formulations for exfoliating and cleansing products.

Xanthan gum polysaccharide finds application in the stabilization of gel-based suspensions for ceramic slip casting in pottery and ceramics.
Xanthan gum polysaccharide is employed in the formulation of gel-based adhesives for bonding and laminating applications in various industries.



DESCRIPTION


Xanthan gum polysaccharide is a polysaccharide, which is a type of large molecule composed of repeating sugar units.
Xanthan gum polysaccharide is produced through fermentation by the bacterium Xanthomonas campestris.
The chemical structure of xanthan gum consists of a backbone made up of repeating glucose, mannose, and glucuronic acid units, with side chains attached to some of the glucose units.

Xanthan gum is a polysaccharide derived from the fermentation of Xanthomonas campestris bacteria.
Xanthan gum polysaccharide is composed of repeating units of glucose, mannose, and glucuronic acid.

Xanthan gum polysaccharide is known for its high viscosity and thickening properties.
Xanthan gum polysaccharide forms a stable and pseudoplastic (shear-thinning) gel in aqueous solutions.

Xanthan gum polysaccharide has an excellent water-holding capacity, contributing to its role as a powerful thickener.
Xanthan gum polysaccharide is widely used in the food industry to enhance the texture and stability of various products.
Xanthan gum polysaccharide is often employed in gluten-free baking to mimic the viscoelastic properties of gluten.

In the cosmetic and personal care industry, it is utilized in creams, lotions, and other formulations for its thickening and stabilizing effects.
Xanthan gum polysaccharide is compatible with a wide range of ingredients, making it a versatile additive.
Xanthan gum polysaccharide exhibits remarkable stability over a broad range of temperatures and pH levels.
Xanthan gum polysaccharide is resistant to shear forces, making it suitable for applications in high-shear environments.
Xanthan gum polysaccharide provides a smooth and creamy mouthfeel in food products like salad dressings and ice creams.

Xanthan gum polysaccharide is often used in conjunction with other thickeners and stabilizers to achieve specific texture and viscosity goals.
Xanthan gum polysaccharide forms clear solutions, avoiding cloudiness in transparent formulations.
In the pharmaceutical industry, it is employed as a suspending agent for drug formulations.

Xanthan gum polysaccharide is biodegradable, environmentally friendly, and generally regarded as safe (GRAS) for consumption.
Xanthan gum polysaccharide is resistant to enzymatic degradation, contributing to its long shelf life.

Xanthan gum polysaccharide is highly efficient at low concentrations, making it a cost-effective additive.
Xanthan gum is produced through a fermentation process, making it suitable for vegetarian and vegan applications.
Due to its thickening properties, it is used in enhanced oil recovery processes in the petroleum industry.
Xanthan gum polysaccharide is soluble in cold and hot water, facilitating its incorporation into various formulations.
Xanthan gum polysaccharide is an anionic polymer, meaning it carries a negative charge in solution.

Xanthan gum polysaccharide is utilized in the production of cleaning products to enhance the viscosity and cling of formulations.
Xanthan gum polysaccharide is compatible with a wide range of salts and can be used in saline solutions.
Xanthan gum polysaccharide's versatility extends to applications in agriculture, textiles, and other industrial sectors due to its rheological and stabilizing properties.



PROPERTIES


Physical state: solid
Color: No data available
Odor: No data available
Chemical formula: C35H49O29 (monomer)
Molar mass: 933.748 g·mol−1



FIRST AID


Inhalation:

If Xanthan gum dust is inhaled and causes respiratory irritation, remove the affected person to fresh air.
Provide artificial respiration if breathing is difficult or has stopped.
Seek medical attention if respiratory symptoms persist.


Skin Contact:

In case of skin contact, wash the affected area with plenty of water.
Remove contaminated clothing and shoes.
If irritation or redness develops, seek medical advice.


Eye Contact:

In case of eye contact, rinse the eyes thoroughly with water for at least 15 minutes, lifting the eyelids occasionally.
If irritation persists, seek medical attention.


Ingestion:

If a significant amount of Xanthan gum is ingested and adverse reactions occur, seek medical attention.
Do not induce vomiting unless directed to do so by medical personnel.


General First Aid:

If any unusual symptoms occur after exposure to Xanthan gum, seek medical advice promptly.
Provide the medical professional with information about the product and the circumstances of exposure.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling Xanthan gum in its powdered form, wear appropriate PPE, including safety glasses or goggles, gloves, and a dust mask to minimize the risk of inhalation and skin contact.

Ventilation:
Ensure adequate ventilation in areas where Xanthan gum is handled to disperse airborne dust and maintain air quality.

Avoiding Contamination:
Prevent contamination of Xanthan gum by using clean utensils and equipment.
Ensure that containers are tightly sealed when not in use to prevent moisture absorption and clumping.

Avoiding Combustible Materials:
Keep Xanthan gum away from combustible materials and open flames, as it is not flammable.
However, excessive dust in the air can pose a dust explosion hazard.

Static Electricity:
Minimize the potential for static electricity buildup by using grounded equipment and avoiding rapid pouring or handling that may generate static charges.


Storage:

Temperature:
Store Xanthan gum in a cool, dry place.
It is generally stable over a broad temperature range, but avoiding extreme temperatures is advisable.

Moisture Control:
Prevent exposure to excessive moisture, as Xanthan gum can form lumps or clumps when it absorbs water.
Store in airtight containers or packaging to maintain product integrity.

Separation from Incompatible Substances:
Store Xanthan gum away from strong acids, alkalis, and oxidizing agents, as these may affect its stability and performance.

Avoiding Contamination:
Keep storage containers clean and free from residues to avoid contamination.

Stacking and Handling Packages:
When storing packaged Xanthan gum, stack bags or containers in a way that minimizes the risk of crushing or damage.
Follow manufacturer recommendations for stacking limitations.

Expiration Date:
Take note of the product's expiration date and adhere to it to ensure optimal quality and performance.

Labeling:
Ensure that containers are properly labeled with necessary information, including product name, lot number, and any safety precautions.

Separation from Strong Odors:
Store Xanthan gum away from strong-smelling substances, as it can absorb odors.

Emergency Measures:
In case of a spill or leakage, follow appropriate emergency measures, including wearing protective equipment and using absorbent materials to contain and clean up the spill.

Regular Inspection:
Regularly inspect stored Xanthan gum for signs of deterioration, contamination, or packaging damage. Remove any compromised product from storage.


Transportation:

Secure Packaging:
Ensure that Xanthan gum is transported in secure packaging to prevent damage or spillage during transit.

Compliance with Regulations:
Adhere to transportation regulations and guidelines for the safe handling and transport of Xanthan gum.

Notification of Authorities:
In case of spillage during transportation, follow appropriate procedures for notifying relevant authorities and implementing cleanup measures.



SYNONYMS


Xanthan polymer
Xanthomonas gum
Bacterial gum
Corn sugar polymer
Microbial gum
Xanthomonas polysaccharide
Xanthomonas campestris polysaccharide
Xanthan gum biopolymer
Xanthomonas campestris exopolysaccharide
Xanthan gum biogum
Xanthan gum biopolymer
Xanthomonas campestris sugar gum
Bacterial exopolysaccharide
Xanthomonas fermentation gum
Microbial polysaccharide
Xanthomonas campestris thickener
Corn sugar thickening agent
Xanthomonas campestris hydrocolloid
Xanthomonas campestris stabilizer
Xanthan microbial gum
Xanthomonas campestris rheology modifier
Xanthomonas campestris gelling agent
Bacterial fermentation gum
Xanthomonas campestris food additive
Xanthomonas campestris industrial gum
XIAMETER MEM 0949
DESCRIPTION:
XIAMETER MEM 0949 Emulsion is a 35% cationic emulsion of an amine-functional silicone polymer.
The amodimethicone actives are delivered in an opaque, low viscosity liquid with a neutral pH.
XIAMETER MEM 0949 was developed as a conditioning additive for hair care products such as shampoos, conditioners, styling aids and hair colorants.


TYPICAL PROPERTIES OF XIAMETER MEM 0949:
INCI Name: Amodimethicone (and) Cetrimonium Chloride (and) Trideceth-12.
Color Milky: white
Physical form Water-thin liquid
Silicone content: 35 %w/w
Viscosity at 25°C (77°F): 5 mm2/s
Emulsifier type: Cationic
pH: 7.5
Suitable diluent: Water
Form : Liquid
Colour : White
Boiling point/range : 100 °C
Flash point : > 100 °C (Closed Cup)
Explosive properties : No
Specific Gravity : 0.99
Viscosity : 5 cSt at 25°C.
Oxidizing properties : No


XIAMETER MEM 0949 provides easy formulation and good dilution stability.
In hair care products, XIAMETER MEM 0949 reduces combing time on wet hair and does not give a heavy effect on dried hair.
A 35% cationic emulsion of an aminofunctional silicone polymer, contains non-tallow surfactant, but does not contain alkylphenol ethoxylate (APE) emulsifiers for use in hair care applications.

XIAMETER MEM 0949 is a 35% cationic emulsion of an amine-functional silicone polymer.
XIAMETER MEM 0949 contains a non-tallow surfactant and does not contain alkylphenol ethoxylate (APE) emulsifiers.

XIAMETER MEM 0949 provides easy formulation, good dilution stability, shine and soft feel on dried hair.
XIAMETER MEM 0949 offers durability, ease of wet & dry combing, detangling, reduced dry time, slipperiness, color & thermal protection, fast dry and volume.
XIAMETER MEM 0949 Emulsion finds application in formulating 2-in-1 shampoos, conditioners, styling aids, hair colorants, perms and leave-on products.
XIAMETER MEM 0949 is non-GMO and Vegan suitable.



BENEFITS OF XIAMETER MEM 0949:
XIAMETER MEM 0949 Does not contain ingredients of animal origin (Suitable for Vegan)
XIAMETER MEM 0949 has not been tested on animals by or on behalf of Dow Chemical
XIAMETER MEM 0949 is Non-GMO*

XIAMETER MEM 0949 Enables ease of formulation
XIAMETER MEM 0949 Enables dilution in water
XIAMETER MEM 0949 Reduces wet combing
XIAMETER MEM 0949 Imparts a light feel.

XIAMETER MEM 0949 is Easy to formulate into hair treatment products
XIAMETER MEM 0949 is Dilutable in water
XIAMETER MEM 0949 Reduced combing time on wet hair
XIAMETER MEM 0949 Does not give a heavy effect on dried hair

APPLICATIONS OF XIAMETER MEM 0949:
XIAMETER MEM 0949 is A very good conditioning additive especially when formulated into leave-on and styling products
XIAMETER MEM 0949 Can be used to formulate other types of products such as perms and colorants
XIAMETER MEM 0949 is Conditioning agent

USES OF XIAMETER MEM 0949:
To optimize the dispersion of XIAMETER MEM-0949 Emulsion into the final formulation, it is recommended to add it slowly at the end of the procedure at a temperature below 40°C (104°F) with continuous mixing or stirring.
Recommended use levels for conditioners is 5% and styling products 0.5 to 5.0%.

ATTENTION: Sample formulations are provided for illustrative purposes only.
Dow does not warrant their merchantability, fitness for use, performance, efficacy, safety or freedom from patent infringement.
They are not commercial formulations and have not been subjected to extensive testing.
It is your responsibility to thoroughly test any formulation before use.

USAGE LIFE AND STORAGE
XIAMETER MEM-0949 should be stored at or below 32°C (89.6°F) in original, unopened containers.
XIAMETER MEM-0949 is susceptible to microbial contamination.
Please use appropriate storage and handling procedures to prevent contamination.

LIMITATIONS
XIAMETER MEM-0949 is neither tested nor represented as suitable for medical or pharmaceutical uses.

HEALTH AND ENVIRONMENTAL INFORMATION
To support customers in their product safety needs, Dow has an extensive Product Stewardship organization and a team of product safety and regulatory compliance specialists available in each area.

DISPOSAL CONSIDERATIONS
Dispose in accordance with all local, state (provincial) and federal regulations.
Empty containers may contain hazardous residues.
XIAMETER MEM-0949 and its container must be disposed in a safe and legal manner.
It is the user’s responsibility to verify that treatment and disposal procedures comply with local, state (provincial) and federal regulations.

SAFETY INFORMATION ABOUT XIAMETER MEM 0949:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.




XIAMETER MEM-1784 EMULSION
DESCRIPTION:
XIAMETER MEM-1784 Emulsion is a 50% anionic emulsion of a high molecular weight polydimethylsiloxane for cosmetic use only.
XIAMETER MEM-1784 Emulsion improves wet combing, leaves hair with a soft feel, improves hair shine and conditions skin.
XIAMETER MEM-1784 Emulsion has no impact on either lather quantity or quality and is ideal for use in in 2-in-1 products.


INCI Name: Dimethiconol (and) TEA-Dodecylbenzenesulfonate


XIAMETER MEM-1784 Emulsion is a 50% anionic emulsion of a high molecular weight polydimethylsiloxane
In 2-in-1 shampoos, it improves the wet combing and imparts a soft feel to the hair as well as improving shine and in 2-in-1 shower gels, it leaves the skin more supple, less dry and with a silky feel.
A 50 percent anionic emulsion of high molecular weight OH functional polydimethylsiloxane for use in shower gels and hair care applications.

XIAMETER MEM-1784 Emulsion acts as a conditioning agent.
XIAMETER MEM-1784 is a 50% anionic emulsion of high molecular weight polydimethylsiloxane.
XIAMETER MEM-1784 contains dimethyl as internal phase functionality.
XIAMETER MEM-1784 offers improved wet- & dry combing, shine, skin conditioning and sensory enhancement, without effecting foam properties at all.

XIAMETER MEM-1784 offers soft feel to hair. In 2-in-1 shower gels, it leaves the skin supple, less dry and silky.
XIAMETER MEM-1784 contains methylchloroisothiazolinone and methylisothiazolinone as preservatives.
XIAMETER MEM-1784 Emulsion finds application in formulating 2-in-1 shampoos and skin-care products.
XIAMETER MEM-1784 is non-GMO and Vegan suitable

USES OF XIAMETER MEM-1784 EMULSION:
XIAMETER MEM-1784 Emulsion is For cosmetic use only
XIAMETER MEM-1784 Emulsion is A very good additive for 2-in-1 products
XIAMETER MEM-1784 Emulsion is used In 2-in-1 shampoos, it improves the wet combing and imparts a soft feel to the hair as well as improving shine

XIAMETER MEM-1784 Emulsion has no impact on either lather quantity or quality. The recommended concentration level is 2 to 4%
In 2-in-1 shower gels, it leaves the skin more supple, less dry and with a silky feel

BENEFITS OF XIAMETER MEM-1784 EMULSION:
XIAMETER MEM-1784 Emulsion Does not contain ingredients of animal origin (Suitable for Vegan)
XIAMETER MEM-1784 Emulsion has not been tested on animals by or on behalf of Dow Chemical
Non-GMO*

Dow does not expect XIAMETER MEM-1784 Emulsion to be classified as nanomaterial*
XIAMETER MEM-1784 Emulsion has No animal cross contamination
XIAMETER MEM-1784 Emulsion has No porcine contamination

XIAMETER MEM-1784 Emulsion Improves wet combing
XIAMETER MEM-1784 Emulsion Imparts a soft feel
XIAMETER MEM-1784 Emulsion Improves shine

XIAMETER MEM-1784 Emulsion Imparts conditioning
XIAMETER MEM-1784 Emulsion Does not impact foam properties

CHEMICAL AND PHYSICAL PROPERTIES OF XIAMETER MEM-1784 EMULSION:
Silicone content % 50
Internal phase viscosity mm2/s > 1 million
Color White to off-white
Viscosity at 25°C mm2/s 20
pH 6–8
Suitable diluent Water
Emulsifier type Anionic
Preservative (INCI Name) Methyl chloro isothiazolinone and Methyl isothiazolinone
Usable Life and Storage:
Product should be stored at or below 32°C (90°F) in original, unopened containers


SAFETY INFORMATION ABOUT XIAMETER MEM-1784 EMULSION:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product

XIAMETER MEM-2664
Xiameter MEM-2664 Xiameter MEM-2664 Emulsion is a non-ionic emulsion of a high molecular weight polydimethyl-siloxane. It delivers high-molecular-weight dimethicone through a water-based system. This product is for use in a variety of hair care applications where the benefits of a high viscosity dimethicone are desired. INCI Name: Dimethicone (and) Laureth-4 (and) Laureth-23 Typical Properties Hair Care Benefits Enhanced Dry Combing, Enhanced Wet Combing, Heat Protection Internal Phase Functionality Dimethyl Surfactant Type Nonionic Features & Benefits • Hair applications Applications • Xiameter MEM-2664 Emulsion is for use in a variety of hair care applications where the benefits of a high viscosity dimethicone are desired. Typical Properties Specification Writers: These values are not intended for use in preparing specifications. Test Unit Value Appearance Milky white Viscosity @ 25°C (77°F) cSt < 200 pH 2.0–5.0 Silicone content % 50 Specific gravity at 25°C (77°F) 0.99 Description Xiameter MEM-2664 Emulsion is a non-ionic emulsion of a high molecular weight polydimethyl-siloxane. How To Use To best stabilize Xiameter MEM-2664 Emulsion in a formulation, add it slowly, at the end of the process, at a temperature below 40°C (104°F) with smooth continuous mixing or stirring. For leave-on and rinse-off conditioners and shampoos the recommended use level is 2% or greater. Usable Life And Storage Product should be stored at or below 25°C (77°F) in original, unopened containers. The emulsion can freeze at 0°C (32°F), so adequate precautions should be taken. Limitations This product is neither tested nor represented as suitable for medical or pharmaceutical uses. Not intended for human injection. Not intended for food use. Health And Environmental Information To support customers in their product safety needs, Dow has an extensive Product Stewardship organization and a team of product safety and regulatory compliance specialists available in each area. For further information, please see our website, www.consumer.dow.com or consult your local Dow representative. Xiameter MEM-2664 Emulsion is designed to meet the need for paraben-free claims in hair care products, and where the benefits of a high viscosity dimethicone are desired; it is the paraben-free counterpart to the Xiameter MEM-1664 Emulsion. This nonionic emulsion of high molecular weight polydimethylsiloxane is recommended at 2% or greater in leave-on and rinse-off conditioners and shampoos. Origin(s): Petrochemical Recommended Use levels: MIN: 2.0 MAX: 2.0 Claims Hair Care Conditioning Feel Shine Function: Surfactants Applications: Conditioners, Hair care, Shampoos Usage level: 2% Xiameter MEM-2664 Emulsion is a non-ionic emulsion of a high molecular weight polydimethyl-siloxane. To support the creation of hair care products that are both effective and consumer-preferred, the Xiameter brand has introduced a paraben-free silicone emulsion for hair conditioning applications—Xiameter MEM-2664 Emulsion. “This emulsion is similar to Xiameter MEM-1664 Emulsion, a proven hair-conditioning agent. The only difference is that Xiameter MEM-2664 Emulsion contains a non-paraben preservative,” explained Kevin Murphy, global market director. Both products enable formulators to deliver high-molecular-weight dimethicone through a water-based system. Both can be used to add valuable conditioning and wet- and dry-combing benefits to shampoos and leave-in and rinse-off conditioners. To support the creation of hair care products that are both effective and consumer-preferred, the Xiameter brand has introduced a new paraben-free silicone emulsion for hair conditioning applications – Xiameter MEM-2664 Emulsion. Today’s consumers are becoming increasingly interested in what their personal care products contain and are actively reading product labels. “Formulators who are responding to consumer desires for paraben-free products need alternative ingredients that are both proven and high-performing,” said Kevin Murphy, global market director. “That’s why we added Xiameter MEM-2664 Emulsion to our hair care line. “This emulsion is similar to Xiameter MEM-1664 Emulsion, a proven hair-conditioning agent. The only difference is that Xiameter MEM-2664 Emulsion contains a non-paraben preservative,” Murphy said. Both products enable formulators to deliver high-molecular-weight dimethicone through a water-based system. Both can be used to add valuable conditioning and wet- and dry-combing benefits to shampoos and leave-in and rinse-off conditioners. Xiameter MEM-2664 emulsion is a non-ionic emulsion of a high molecular weight polydimethylsiloxane. It is ideal for use in a variety of hair care and skin care applications where the benefit of a high viscosity dimethicone is desired. What Is It? Xiameter MEM-2664 are polyoxyethers of lauryl alcohol. They are a clear, colorless liquids. In cosmetics and personal care products, Xiameter MEM-2664 are used in the formulation of a variety of bath, eye, facial, hair, cleansing and sunscreen products. They are also used in cuticle softeners, deodorants and moisturizing products. Why is it used in cosmetics and personal care products? Xiameter MEM-2664 both function as surfactants. Laureth-4 functions as a surfatant - emulsfying agent, while Laureth-23 functions as a surfactant - cleansing agent and a surfactant - solubilizing agent. Scientific Facts: Xiameter MEM-2664 are produced by reacting ethylene oxide with lauryl alcohol. The numerical designation refers to the average number of repeating ethylene oxide units in the molecule. As the numerical value of Laureths increases, the viscosity of the ingredient increases until they become white, waxy solids. Polydimethylsiloxane (Xiameter MEM-2664), also known as dimethylpolysiloxane or dimethicone, belongs to a group of polymeric organosilicon compounds that are commonly referred to as silicones.[1] Xiameter MEM-2664 is the most widely used silicon-based organic polymer due to its versatility and properties leading to many applications.[2] It is particularly known for its unusual rheological (or flow) properties. Xiameter MEM-2664 is optically clear and, in general, inert, non-toxic, and non-flammable. It is one of several types of silicone oil (polymerized siloxane). Its applications range from contact lenses and medical devices to elastomers; it is also present in shampoos (as it makes hair shiny and slippery), food (antifoaming agent), caulking, lubricants and heat-resistant tiles. Structure The chemical formula for Xiameter MEM-2664 is CH3[Si(CH3)2O]nSi(CH3)3, where n is the number of repeating monomer [SiO(CH3)2] units.[3] Industrial synthesis can begin from dimethyldichlorosilane and water by the following net reaction: The polymerization reaction evolves hydrochloric acid. For medical and domestic applications, a process was developed in which the chlorine atoms in the silane precursor were replaced with acetate groups. In this case, the polymerization produces acetic acid, which is less chemically aggressive than HCl. As a side-effect, the curing process is also much slower in this case. The acetate is used in consumer applications, such as silicone caulk and adhesives. Branching and capping Hydrolysis of Si(CH3)2Cl2 generates a polymer that is terminated with silanol groups (−Si(CH3)2OH]). These reactive centers are typically "capped" by reaction with trimethylsilyl chloride: 2 Si(CH3)3Cl + [Si(CH3)2O]n−2[Si(CH3)2OH]2 → [Si(CH3)2O]n−2[Si(CH3)2O Si(CH3)3]2 + 2 HCl Silane precursors with more acid-forming groups and fewer methyl groups, such as methyltrichlorosilane, can be used to introduce branches or cross-links in the polymer chain. Under ideal conditions, each molecule of such a compound becomes a branch point. This can be used to produce hard silicone resins. In a similar manner, precursors with three methyl groups can be used to limit molecular weight, since each such molecule has only one reactive site and so forms the end of a siloxane chain. Well-defined Xiameter MEM-2664 with a low polydispersity index and high homogeneity is produced by controlled anionic ring-opening polymerization of hexamethylcyclotrisiloxane. Using this methodology it is possible to synthesize linear block copolymers, heteroarm star-shaped block copolymers and many other macromolecular architectures. The polymer is manufactured in multiple viscosities, ranging from a thin pourable liquid (when n is very low), to a thick rubbery semi-solid (when n is very high). Xiameter MEM-2664 molecules have quite flexible polymer backbones (or chains) due to their siloxane linkages, which are analogous to the ether linkages used to impart rubberiness to polyurethanes. Such flexible chains become loosely entangled when molecular weight is high, which results in Xiameter MEM-2664' unusually high level of viscoelasticity. Mechanical properties Xiameter MEM-2664 is viscoelastic, meaning that at long flow times (or high temperatures), it acts like a viscous liquid, similar to honey. However, at short flow times (or low temperatures), it acts like an elastic solid, similar to rubber. Viscoelasticity is a form of nonlinear elasticity that is common amongst noncrystalline polymers.[4] The loading and unloading of a stress-strain curve for Xiameter MEM-2664 do not coincide; rather, the amount of stress will vary based on the degree of strain, and the general rule is that increasing strain will result in greater stiffness. When the load itself is removed, the strain is slowly recovered (rather than instantaneously). This time-dependent elastic deformation results from the long-chains of the polymer. But the process that is described above is only relevant when cross-linking is present; when it is not, the polymer Xiameter MEM-2664 cannot shift back to the original state even when the load is removed, resulting in a permanent deformation. However, permanent deformation is rarely seen in Xiameter MEM-2664, since it is almost always cured with a cross-linking agent. If some Xiameter MEM-2664 is left on a surface overnight (long flow time), it will flow to cover the surface and mold to any surface imperfections. However, if the same Xiameter MEM-2664 is poured into a spherical mold and allowed to cure (short flow time), it will bounce like a rubber ball.[3] The mechanical properties of Xiameter MEM-2664 enable this polymer to conform to a diverse variety of surfaces. Since these properties are affected by a variety of factors, this unique polymer is relatively easy to tune. This enables Xiameter MEM-2664 to become a good substrate that can easily be integrated into a variety of microfluidic and microelectromechanical systems.[5][6] Specifically, the determination of mechanical properties can be decided before Xiameter MEM-2664 is cured; the uncured version allows the user to capitalize on myriad opportunities for achieving a desirable elastomer. Generally, the cross-linked cured version of Xiameter MEM-2664 resembles rubber in a solidified form. It is widely known to be easily stretched, bent, compressed in all directions.[7] Depending on the application and field, the user is able to tune the properties based on what is demanded. Fabric embedded within Xiameter MEM-2664. This technique enables a user to retain a thin layer of Xiameter MEM-2664 as a substrate while achieving a higher stiffness through the insertion of reinforcement. Linear relationship in Sylgard 184 Xiameter MEM-2664 between curing temperature and Young's modulus Overall Xiameter MEM-2664 has a low elastic modulus which enables it to be easily deformed and results in the behavior of a rubber.[8][9][10] Viscoelastic properties of Xiameter MEM-2664 can be more precisely measured using dynamic mechanical analysis. This method requires determination of the material's flow characteristics over a wide range of temperatures, flow rates, and deformations. Because of Xiameter MEM-2664's chemical stability, it is often used as a calibration fluid for this type of experiment. The shear modulus of Xiameter MEM-2664 varies with preparation conditions, and consequently dramatically varies in the range of 100 kPa to 3 MPa. The loss tangent is very low (tan δ ≪ 0.001). Chemical compatibility Xiameter MEM-2664 is hydrophobic.[6] Plasma oxidation can be used to alter the surface chemistry, adding silanol (SiOH) groups to the surface. Atmospheric air plasma and argon plasma will work for this application. This treatment renders the Xiameter MEM-2664 surface hydrophilic, allowing water to wet it. The oxidized surface can be further functionalized by reaction with trichlorosilanes. After a certain amount of time, recovery of the surface's hydrophobicity is inevitable, regardless of whether the surrounding medium is vacuum, air, or water; the oxidized surface is stable in air for about 30 minutes.[11] Alternatively, for applications where long-term hydrophilicity is a requirement, techniques such as hydrophilic polymer grafting, surface nanostructuring, and dynamic surface modification with embedded surfactants can be of use. [12] Solid Xiameter MEM-2664 samples (whether surface-oxidized or not) will not allow aqueous solvents to infiltrate and swell the material. Thus Xiameter MEM-2664 structures can be used in combination with water and alcohol solvents without material deformation. However most organic solvents will diffuse into the material and cause it to swell.[6] Despite this, some organic solvents lead to sufficiently small swelling that they can be used with Xiameter MEM-2664, for instance within the channels of Xiameter MEM-2664 microfluidic devices. The swelling ratio is roughly inversely related to the solubility parameter of the solvent. Diisopropylamine swells Xiameter MEM-2664 to the greatest extent; solvents such as chloroform, ether, and THF swell the material to a large extent. Solvents such as acetone, 1-propanol, and pyridine swell the material to a small extent. Alcohols and polar solvents such as methanol, glycerol and water do not swell the material appreciably.[13] Applications Surfactants and antifoaming agents Xiameter MEM-2664 is a common surfactant and is a component of defoamers.[14] Xiameter MEM-2664, in a modified form, is used as an herbicide penetrant[15] and is a critical ingredient in water-repelling coatings, such as Rain-X.[16] Hydraulic fluids and related applications Dimethicone is also the active silicone fluid in automotive viscous limited slip differentials and couplings. This is usually a non-serviceable OEM component but can be replaced with mixed performance results due to variances in effectiveness caused by refill weights or non-standard pressurizations.[citation needed] Soft lithography Xiameter MEM-2664 is commonly used as a stamp resin in the procedure of soft lithography, making it one of the most common materials used for flow delivery in microfluidics chips.[17] The process of soft lithography consists of creating an elastic stamp, which enables the transfer of patterns of only a few nanometers in size onto glass, silicon or polymer surfaces. With this type of technique, it is possible to produce devices that can be used in the areas of optic telecommunications or biomedical research. The stamp is produced from the normal techniques of photolithography or electron-beam lithography. The resolution depends on the mask used and can reach 6 nm. In biomedical (or biological) microelectromechanical systems (bio-MEMS), soft lithography is used extensively for microfluidics in both organic and inorganic contexts. Silicon wafers are used to design channels, and Xiameter MEM-2664 is then poured over these wafers and left to harden. When removed, even the smallest of details is left imprinted in the Xiameter MEM-2664. With this particular Xiameter MEM-2664 block, hydrophilic surface modification is conducted using plasma etching techniques. Plasma treatment disrupts surface silicon-oxygen bonds, and a plasma-treated glass slide is usually placed on the activated side of the Xiameter MEM-2664 (the plasma-treated, now hydrophilic side with imprints). Once activation wears off and bonds begin to reform, silicon-oxygen bonds are formed between the surface atoms of the glass and the surface atoms of the Xiameter MEM-2664, and the slide becomes permanently sealed to the Xiameter MEM-2664, thus creating a waterproof channel. With these devices, researchers can utilize various surface chemistry techniques for different functions creating unique lab-on-a-chip devices for rapid parallel testing.[5] Xiameter MEM-2664 can be cross-linked into networks and is a commonly used system for studying the elasticity of polymer networks.[citation needed] Xiameter MEM-2664 can be directly patterned by surface-charge lithography. Xiameter MEM-2664 is being used in the making of synthetic gecko adhesion dry adhesive materials, to date only in laboratory test quantities.[20] Some flexible electronics researchers use Xiameter MEM-2664 because of its low cost, easy fabrication, flexibility, and optical transparency.[21] Stereo lithography In stereo lithography (SLA) 3D printing, light is projected onto photocuring resin to selectively cure it. Some types of SLA printer are cured from the bottom of the tank of resin and therefore require the growing model to be peeled away from the base in order for each printed layer to be supplied with a fresh film of uncured resin. A Xiameter MEM-2664 layer at the bottom of the tank assists this process by absorbing oxygen : the presence of oxygen adjacent to the resin prevents it adhering to the Xiameter MEM-2664, and the optically clear Xiameter MEM-2664 permits the projected image to pass through to the resin undistorted. Medicine and cosmetics Activated dimethicone, a mixture of polydimethylsiloxanes and silicon dioxide (sometimes called simethicone), is often used in over-the-counter drugs as an antifoaming agent and carminative.[22][23] It has also been at least proposed for use in contact lenses.[24] Silicone breast implants are made out of a Xiameter MEM-2664 elastomer shell, to which fumed amorphous silica is added, encasing Xiameter MEM-2664 gel or saline solution. [25] In addition, Xiameter MEM-2664 is useful as a lice or flea treatment because of its ability to trap insects.[26] It also works as a moisturizer that is lighter and more breathable than typical oils. Skin Xiameter MEM-2664 is used variously in the cosmetic and consumer product industry as well. For example, Xiameter MEM-2664 can be used in the treatment of head lice on the scalp[26] and dimethicone is used widely in skin-moisturizing lotions where it is listed as an active ingredient whose purpose is "skin protection." Some cosmetic formulations use dimethicone and related siloxane polymers in concentrations of use up to 15%. The Cosmetic Ingredient Review's (CIR) Expert Panel, has concluded that dimethicone and related polymers are "safe as used in cosmetic formulations."[27] Hair Xiameter MEM-2664 compounds such as amodimethicone, are effective conditioners when formulated to consist of small particles and be soluble in water or alcohol/act as surfactants[28][29] (especially for damaged hair[30]), and are even more conditioning to the hair than common dimethicone and/or dimethicone copolyols.[31] Contact Lenses A proposed use of Xiameter MEM-2664 is contact lens cleaning. Its physical properties of low elastic modulus and hydrophobicity have been used to clean micro and nano pollutants from contact lens surfaces more effectively than multipurpose solution and finger rubbing; the researchers involved call the technique PoPPR (polymer on polymer pollution removal) and note that it is highly effective at removing nanoplastic that has adhered to lenses.[32] Flea treatment for pets Dimethicone is the active ingredient in a liquid applied to the back of the neck of a cat or dog from a small one time use dose disposable pipette. The parasite becomes trapped and immoblised in the substance and thus breaks the life cycle of the insect. Foods Xiameter MEM-2664 is added to many cooking oils (as an antifoaming agent) to prevent oil splatter during the cooking process. As a result of this, Xiameter MEM-2664 can be found in trace quantities in many fast food items such as McDonald's Chicken McNuggets, french fries, hash browns, milkshakes and smoothies[33] and Wendy's french fries. Under European food additive regulations, it is listed as E900. Condom lubricant Xiameter MEM-2664 is widely used as a condom lubricant. Domestic and niche uses Many people are indirectly familiar with Xiameter MEM-2664 because it is an important component in Silly Putty, to which Xiameter MEM-2664 imparts its characteristic viscoelastic properties.[37] Another toy Xiameter MEM-2664 is used in is Kinetic Sand. The rubbery, vinegary-smelling silicone caulks, adhesives, and aquarium sealants are also well-known. Xiameter MEM-2664 is also used as a component in silicone grease and other silicone based lubricants, as well as in defoaming agents, mold release agents, damping fluids, heat transfer fluids, polishes, cosmetics, hair conditioners and other applications. Xiameter MEM-2664 has also been used as a filler fluid in breast implants. It can be used as a sorbent for the analysis of headspace (dissolved gas analysis) of food. Safety and environmental considerations According to Ullmann's Encyclopedia, no "marked harmful effects on organisms in the environment" have been noted for siloxanes. Xiameter MEM-2664 is nonbiodegradable, but is absorbed in waste water treatment facilities. Its degradation is catalyzed by various clays.[39] Xiameter MEM-2664 is biocompatible[40], and its used in microfluidic device manufacturing because of that. What Is Xiameter MEM-2664? Is It Safe in Skin and Hair Care? At Puracy, we take natural skincare seriously. Discover what Xiameter MEM-2664 is, how it's used, and why it's more harmful than you might think. What is Xiameter MEM-2664, exactly? You might spot it on skin and hair care labels, but chemical names like “polydimethylsiloxane” can be difficult to decipher when you’re pressed for time. As an eco-friendly brand, Puracy wants to set the record straight about Xiameter MEM-2664 in skincare and hair care – and you’ll never find it in our products. What Is Xiameter MEM-2664? If you've ever used a makeup primer, it probably had some form of Xiameter MEM-2664 (ie. polydimethylsiloxane) in it. Since the molecules of silicone-based polymers are too large for the skin and hair to absorb, these products leave behind a silky/slippery layer. Board-certified dermatologist Dr. Julie Jackson states that Xiameter MEM-2664 “does not interact with the stratum corneum (the top layer of the skin). It works by forming a film that prevents the loss of water through the skin, thus keeping the skin moisturized. It also works as an emollient, filling the spaces between cracks in the skin.” The result? Shinier-looking and smoother-feeling skin and hair. What Is Xiameter MEM-2664 Used for? Hundreds of personal care products use Xiameter MEM-2664 for a more seamless application, including diaper rash creams, moisturizers, hand lotions, and liquid foundations. Most hair care companies use silicones and Xiameter MEM-2664 to coat the hair cuticle and make detangling easier. Is Xiameter MEM-2664 Bad for Skin? According to the FDA and Cosmetic Ingredient Review (CIR), Xiameter MEM-2664 is a safe skincare ingredient that calms irritation, minimizes redness, and protects the skin from further damage. We consulted with Dr. Jackson on this topic, and she agreed that – even though it’s an unnatural, man-made substance, Xiameter MEM-2664 is a good chemically-inert moisturizer and safe for skin. When asked whether Xiameter MEM-2664 is known to clog pores, Dr. Jackson concluded, “There is no evidence that Xiameter MEM-2664 causes acne.” How to Avoid Xiameter MEM-2664 in Shampoo & Conditioner Historically, there have beenvery few eco-friendly hair products which provided the same results as their synthetic counterparts. After years of R&D with expert chemists and testers, Puracy Natural Shampoo and Conditioner are rare examples of Xiameter MEM-2664-free hair products that leave all hair types moisturized, bouncy, and shiny. While reformulating our shampoo and conditioner, the biggest change came from the inclusion of Lexfeel N5. This 100% sustainable and biodegradable emollient seamlessly replicates the effects of both Xiameter MEM-2664 and silicone. We’re proud to be one of the first companies to use this plant-sourced ingredient in our unbelievably effective hair care line. Is Xiameter MEM-2664 Bad for the Environment? The short answer: Yes. Depending on the route your water takes, when Xiameter MEM-2664 (a hydrolyzed chemical) is washed down the drain, it can feed into aquatic environments and impact fish and plant life. The National Center for Biotechnology Information also states that “the use of low molecular weight silicones should be reduced...and the purity of high molecular weight silicones should be monitored.” What is Xiameter MEM-2664 used for? Xiameter MEM-2664 is a silicon-based polymer that, when used in beauty products, gives the formula an incredibly smooth, velvety, slippery feel that you either love or hate (although I'll never understand the people who hate it TBH. I freakin' love the smooth feeling of silicones). But Xiameter MEM-2664 is not only used for its sensory properties—it also helps to temporarily smooth fine lines and wrinkles, functions as an emollient (aka a skin-conditioning agent), and also has some occlusive properties (meaning it prevents water loss by creating a seal or a barrier on your skin). And because of these properties, you'll usually find Xiameter MEM-2664 in your foundations, makeup primers, hair products, moisturizers, etc. Basically, unless a label specifically says it's silicone-free, you can almost guarantee it's in ev-ery-thing. Is Xiameter MEM-2664 safe for skin? Despite what the haters may say, according to the Cosmetic Ingredient Review Panel, Xiameter MEM-2664 is safe when used in cosmetic products. What's more, the CIR Expert Panel also says because of the large molecular weight of Xiameter MEM-2664, it's unlikely that it can be absorbed into the skin in a significant way. Board-certified dermatologist Dhaval G. Bhanusali, MD, isn't concerned either: "I think, all too often, people put things in categories and say, 'all of this is bad,'" he says. "But in this case, I don't know of many colleagues who are concerned with Xiameter MEM-2664 in skincare products." Can Xiameter MEM-2664 clog pores? Now that I've painted the visual of Xiameter MEM-2664 creating a seal on your skin, you're probably wondering if this means your face is gonna be left with crazy clogged pores from using it. But, surprisingly, that's not the case. Dr. Bhanusali says that unlike with other occlusives, Xiameter MEM-2664 isn't really heavy, which is why a lot of people with oily skin tend to like the feel of Xiameter MEM-2664 in their makeup or skincare products. "In general, this isn’t something that dermatologists are actually worried about," says Dr. Bhanusali, and instead, "Xiameter MEM-2664 is sometimes beneficial for acne patients, given the light nature it." And as far as Xiameter MEM-2664 being difficult to remove, Dr. Bhanusali says most cleansers are actually pretty effective at taking it off and recommends using a micellar-based formula, like Bioderma. Why is Xiameter MEM-2664 bad for hair? Although Xiameter MEM-2664 is fine for use on the skin, things get a little trickier when using it on your hair, mainly because it can coat your strands and weigh them down (which is not great for curls or fine hair). But, "if you have dry, damaged hair that's prone to tangles, Xiameter MEM-2664 can help create that sleek, slippery feel, making detangling easy and giving the appearance that the hair is super-conditioned and healthy," says trichologist and creator of Colour Collective, Kerry E. Yates. "Xiameter MEM-2664 is also heavily used in styling products to help 'glue' the cuticles down to create that smooth, shiny effect in hair." But it's this "gluing" mechanism that can also cause problems in the long-run—Xiameter MEM-2664 tends to quickly build up on your strands, preventing water from penetrating your hair cuticle, leaving your hair lank, dry, and damaged. The good news? Silicones can easily be removed by washing with a silicone-free, sulfate-filled cleanser. Yes, it'll be stripping and drying, but it'll also "reset" your strands, so if you're a big silicone user, try a reset wash once every few weeks to clear the buildup. As far as worries of hair loss go, Dr. Bhanusali says Xiameter MEM-2664 is not really something they consider or worry about, but as trichologist and creator of Colour Collective, Kerry E. Yates, explains it, the concern with Xiameter MEM-2664 in hair products has more to do with the effect it has on the health and quality of your strands. Sooo, does Xiameter MEM-2664 build up on hair? In short, yes. The reason why you might experience dry hair from using a Xiameter MEM-2664-based formula is that the product builds up, which prevents the hair from achieving a proper moisture balance. This is why excess use of Xiameter MEM-2664 can result in dry, brittle ends that are prone to breakage. For that reason, Yates argues that not all hair types and textures should use silicones—it can make fine hair look limp and oily, and it can make curly and coily hair textures drier and more brittle. "People with curly, coily hair should avoid using Xiameter MEM-2664, as the hair is already in a fragile state," says Yates. "By contributing to that dryness, you intensify the level of breakage," Yates says. The bottom line Just because the experts say Xiameter MEM-2664 is not the enemy the internet has made it out to be, it doesn't mean you have to use it. Xiameter MEM-2664 has its pros and cons, so if you've read the above and decided you still don't want to use it, don't! No one's making you! Uses This medication is used as a moisturizer to treat or prevent dry, rough, scaly, itchy skin and minor skin irritations (e.g., diaper rash, skin burns from radiation therapy). Emollients are substances that soften and moisturize the skin and decrease itching and flaking. Some products (e.g., zinc oxide, white petrolatum) are used mostly to protect the skin against irritation (e.g., from wetness).Dry skin is caused by a loss of water in the upper layer of the skin. Emollients/moisturizers work by forming an oily layer on the top of the skin that traps water in the skin. Petrolatum, lanolin, mineral oil and Xiameter MEM-2664 are common emollients. Humectants, including glycerin, lecithin, and propylene glycol, draw water into the outer layer of skin. Many products also have ingredients that soften the horny substance (keratin) that holds the top layer of skin cells together (including urea, alpha hydroxy acids such as lactic/citric/glycolic acid, and allantoin). This helps the dead skin cells fall off, helps the skin keep in more water, and leaves the skin feeling smoother and softer. How to use Xiameter MEM-2664 2 % Topical Cream Skin Protectants Use this product as directed. Some products require priming before use. Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist. Some products need to be shaken before use. Check the label to see if you should shake the bottle well before using. Apply to the affected areas of the skin as needed or as directed on the label or by your doctor. How often you apply the medication will depend on the product and your skin condition. To treat dry hands, you may need to use the product every time you wash your hands, applying it throughout the day. Follow all the directions on the label for proper use. Apply to the skin only. Avoid sensitive areas such as your eyes, inside your mouth/nose, and the vaginal/groin area, unless the label or your doctor directs you otherwise. Check the label for directions about any areas or types of skin where you should not apply the product (e.g., on the face, any areas of broken/chapped/cut/irritated/scraped skin, or on a recently shaved area of the skin). Consult your doctor or pharmacist for more details.
XIAMETER PMX 0345
XIAMETER PMX 0345 Cyclosiloxane Blend is a blend of volatile polydimethylcyclosiloxane composed of cyclohexasiloxane and cyclopentasiloxane.
XIAMETER PMX 0345 is clear, tasteless, essentially odorless, non-greasy and non-stinging.

XIAMETER PMX 0345 Cyclosiloxane Blend is a base fluid in a number of personal care products, with excellent spreading, easy rub-out and lubrication properties and unique volatility characteristics.
XIAMETER PMX 0345 can be used in antiperspirants, deodorants, hair sprays, cleansing creams, skin creams, lotions, bath oils, suntan and shaving products, make-up and nail polishes.

FEATURES of XIAMETER PMX 0345:
• Volatile carrier
• Compatible with a wide range of cosmetic ingredients
• Low surface tension

BENEFITS of XIAMETER PMX 0345:
• Excellent spreading
• Leaves no residue or build up
• Detackification

APPLICATIONS of XIAMETER PMX 0345:
• A base fluid in a number of personal care products, with excellent spreading, easy rub-out and lubrication properties and unique volatility characteristics.
• Antiperspirants, deodorants, hair sprays, cleansing creams, skin creams, lotions, bath oils, suntan and shaving products, make-up, and nail polishes.
• Can also be used as an additive to powder make-up, colognes and pre-shaves.
• In sticks, it has the right balance between volatility and spreading

XIAMETER PMX 0345 Cyclosiloxane blend acts as a carrier.
XIAMETER PMX 0345 is a blend of volatile polydimethylcyclosiloxane composed of cyclohexasiloxane and cyclopentasiloxane.
XIAMETER PMX 0345 is used alone or blended with other cosmetic fluids to provide a fluid base for a variety of cosmetic ingredients.
XIAMETER PMX 0345 offers excellent spreading, easy rub-out, detackification, low surface tension and lubrication properties together with unique volatility characteristics.

XIAMETER PMX 0345 leaves no oily residue or build-up.
Moreover, XIAMETER PMX 0345 is non-greasy & non-stinging and is compatible with a wide range of cosmetic ingredients.
In sticks, XIAMETER PMX 0345 provides right balance between volatility and spreading.
XIAMETER PMX 0345 Cyclosiloxane blend finds application in formulating antiperspirants, deodorants, hair sprays, cleansing creams, make-up, skin creams, lotions, bath oils, nail polishes, sun-tan and shaving products.
XIAMETER PMX 0345 can also be used as an additive to powder make-up, colognes and pre-shaves.
XIAMETER PMX 0345 complies with NZIoC, REACH, TSCA, AICS, IECSC, ENCS/ISHL, KECI, TCSI, PICCS and DSL.

Uses of XIAMETER PMX 0345:
-Antiperspirants
-Deodorants
-Hair sprays
-Cleansing creams
-Skin creams
-Lotions
-Bath oils
-Suntan
-Shaving products
-Make-up
-Nail polishes
-An additive to powder make-up
-Colognes
-Pre-shaves

Benefits of XIAMETER PMX 0345:
-Volatile carrier
-Compatible with a wide range of cosmetic ingredients
-Low surface tension
-Excellent spreading
-Leaves no residue or build up
-Detackification
-Easy rubout and lubrication properties
-Unique volatility characteristics
-In sticks, XIAMETER PMX 0345 has the right balance between volatility and spreading
-Does not contain ingredients of animal origin (Suitable for Vegan)
-XIAMETER PMX 0345 has not been tested on animals by or on behalf of Dow Chemical
-Non-GMO*
-Based on our knowledge available at this time, Dow does not expect this product to be classified as nanomaterial*
-No animal cross contamination
-No porcine contamination

Description of XIAMETER PMX 0345:
XIAMETER PMX 0345 Cyclosiloxane Blend is a blend of volatile polydimethylcyclosiloxane composed of cyclohexasiloxane and cyclopentasiloxane.
XIAMETER PMX 0345 is clear, tasteless, essentially odorless, non-greasy and non-stinging.

A blend of polydimethylcyclosiloxanes composed mainly of cyclopentasiloxane and cyclohexasiloxane for use in skincare, suncare, color cosmetics, hair treatments, and antiperspirant / deodorant applications.
INCI Name: Cyclopentasiloxane (and) Cyclohexasiloxane

Features & Benefits of XIAMETER PMX 0345:
• Volatile carrier
• Compatible with a wide range of cosmetic ingredients
• Low surface tension
• Excellent spreading
• Leaves no residue or build up
• Detackification

Applications of XIAMETER PMX 0345:
• A base fluid in a number of personal care products, with excellent spreading, easy rubout and lubrication properties and unique volatility characteristics.
• Antiperspirants, deodorants, hair sprays, cleansing creams, skin creams, lotions, bath oils, suntan and shaving products, make-up, and nail polishes.
• XIAMETER PMX 0345 can also be used as an additive to powder make-up, colognes and pre-shaves.
• In sticks, XIAMETER PMX 0345 has the right balance between volatility and spreading.

Boiling Point: 217 °C
Cyclotetrasiloxane Content: < 0.1 %
Flash Point, Closed Cup: 77 °C
Freezing Point: < -50 °C
Kinetic / Kinematic Viscosity: 6 Centistokes
Low Odor: Yes

XIAMETER PMX 0345 is a base fluid in a number of personal care products, with excellent spreading, easy rub-out and lubrication properties and unique volatility characteristics.
XIAMETER PMX 0345 can be used in antiperspirants, deodorants, hair sprays, cleansing creams, skin creams, lotions, bath oils, suntan and shaving products, makeup and nail polishes.
XIAMETER PMX 0345 can also be used as an additive to powder makeup, colognes and pre-shaves.
In sticks, XIAMETER PMX 0345 has the right balance between volatility and spreading.
A blend of polydimethylcyclosiloxanes composed mainly of cyclopentasiloxane and cyclohexasiloxane for use in skincare, suncare, color cosmetics, hair treatments, and antiperspirant / deodorant applications.

Material Type: Fluid Blend
Refractive Index: 1.398
Shelf Life: 900 Days
Specific Gravity @ 25°C: 0.957
Surface Tension (1% actives, 25 °C): 20.8 mN/m
Water Content: 0.025 %

How to Use XIAMETER PMX 0345:
Cyclosiloxane Blend may be used alone or blended with other cosmetic fluids to provide a fluid base for a variety of cosmetic ingredients.
XIAMETER PMX 0345 features good solubility in most anhydrous alcohols and in many cosmetic solvents.
XIAMETER PMX 0345 Cyclosiloxane Blend is a volatile fluid with appreciable vapor pressure at ambient temperature.

Detackification: Yes
Dry: During Application Feel
Improved Spreading: Yes
Increase: Glide
Non-Occlusive: Yes
Non-Staining on Clothing: Yes
Oil Control Benefits: Reduce Greasiness
Performance Benefits: Sensory Enhancer

How to Use (Cont.)
By using blends of cyclomethicones this difference in volatility can be used to vary the residence time of the silicone on the skin.
Unlike other volatile carriers used in the personal care industry, volatile silicone fluids do not cool the skin when they evaporate.
XIAMETER PMX 0345 is a consequence of their unusually low heat of vaporization.

Pet and Animal Care Benefits: Ease of Wet Combing / Detangling, Reduced Dry Time
Quick Absorption: Yes
Reduced: Drying Time, Greasiness, Tackiness
Skin Texture Benefits: Sensory Enhancer (light feel)

Active Compatibility: Chemical Sunscreens, Natural Oils
Formulating Benefits: Volatile Carrier

Description of XIAMETER PMX 0345:
A volatile solvent with excellent spreading easy rub-out and lubrication properties together with unique low volatility.
The silicone solvent can be used as a solvent in polishes to improve spreadability and give lubricity.
XIAMETER PMX 0345 does not have the same flammability issue of traditional solvents and has a low odour.
XIAMETER PMX 0345 is less volatile than Xiameter PMX-0245.

Usable Life and Storage
Product should be stored at or below 25°C (77°F) in the original unopened containers.
Care should be taken when handling volatile fluids at temperatures 10°C below the quoted flash point.
As with any flammable material, containers should be kept tightly closed and away from heat, sparks, open flames, and other sources of ignition.
Limitations This product is neither tested nor represented as suitable for medical or pharmaceutical uses.
Not intended for human injection.
Not intended for food use.

APPLICATIONS of XIAMETER PMX 0345:
-A base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics.
-Can be used in antiperspirants, deodorants, skin creams, lotions, bath oils, suntan and shaving products, make-up, nail polishes.
-In hair sprays; faster drying time in low VOC formula.
-In cleansing products; XIAMETER PMX 0345 Cyclotetrasiloxane lifts and removes dirt without leaving any greasy residue or stinging sensation.

TYPICAL PROPERTIES of XIAMETER PMX 0345:
Specification Writers: These values are not intended for use in preparing specifications.

Fluid: Heat of vaporization (25°C/77°F)
XIAMETER™ PMX-0244 Cyclotetrasiloxane: 172
XIAMETER™ PMX-0245 Cyclopentasiloxane: 157
XIAMETER™ PMX-0246 Cyclohexasiloxane: 147
XIAMETER™ PMX-0344 Cyclosiloxane Blend: 168
XIAMETER™ PMX-0345 Cyclosiloxane Blend: 155
Water: 2257
Ethanol: 840
XIAMETER™ PMX-200 Silicone fluid 0.65 cSt: 192
XIAMETER PMX 1503 FLUID
XIAMETER PMX 1503 Fluid is a blend of an ultra high viscosity Dimethiconol in a low viscosity Dimethicone fluid.
This film forming, non-occlusive clear, colorless liquid is long lasting, wash-off resistant, and imparts a silky, lubricious skin feel.
XIAMETER PMX 1503 Fluid can be used in a wide variety of cosmetic and toiletry applications such as skincare, color cosmetics, sun care and shower gels.

CAS: 63148-62-9
MF: C6H18OSi2
MW: 162.38
EINECS: 613-156-5

XIAMETER PMX 1503 Fluid acts as a non-occlusive film forming agent.
XIAMETER PMX 1503 Fluid is a blend of an ultra-high viscosity dimethiconol in a low viscosity dimethicone fluid.
XIAMETER PMX 1503 Fluid imparts silky & lubricious feel and offers shine, wash-off resistance & long lasting effect.
XIAMETER PMX 1503 Fluid provides improved spreading, volume control and increased glide & payout.
XIAMETER PMX 1503 Fluid can reduce syneresis, tackiness & white residue.
XIAMETER PMX 1503 Fluid offers enhanced dry- & wet combing, frizz control, reduced friction, smooth feel and split end repair.
XIAMETER PMX 1503 Fluid finds application in formulating leave-in & rinse-off hair conditioners, color cosmetics, shower gels, sun-care and skin-care products.
XIAMETER PMX 1503 Fluid is non-GMO and Vegan suitable.

XIAMETER PMX 1503 Fluid is made up of a blend of an ultra high viscosity dimethiconol in a low viscosity dimethicone fluid for use in skin care, sun care, and color cosmetic applications.
XIAMETER PMX 1503 Fluid's film forming properties are both non-occlusive with wash-off resistance allowing it to impart a long lasting silky, lubricous feeling on the skin.
XIAMETER PMX 1503 Fluid does not contain ingredients of animal origin, nor has this product been tested on animals by or on behalf making it suitable for vegans.
Any of a large group of siloxane polymers based on a structure consisting of alternate silicon and oxygen atoms with various organic radicals attached to the silicon.
XIAMETER PMX 1503 Fluid is low viscosity liquid polymerized siloxanes with organic side chains.

XIAMETER PMX 1503 Fluid Chemical Properties
Melting point: −59 °C(lit.)
Boiling point: 101 °C(lit.)
Density: 0.963 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.377(lit.)
Fp: >270 °C (518 °F)
Storage temp.: 2-8°C
Solubility: Chloroform (Slightly), Ethyl Acetate (Sparingly), Toluene (Sparingly)
Form: Oily Liquid
Specific Gravity: 0.853
Color: Clear colorless
Odor: Odorless
Water Solubility: PRACTICALLY INSOLUBLE
Merck: 14,8495
Stability: Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System: XIAMETER PMX 1503 Fluid (63148-62-9)

XIAMETER PMX 1503 Fluid is milk-white viscous liquid and is non-volatile and odorless.
XIAMETER PMX 1503 Fluid has a relative density of O.98~1.02.
XIAMETER PMX 1503 Fluid is miscible with benzene, gasoline and other kinds of chlorinated hydrocarbons, aliphatic and aromatic hydrocarbons; it is not soluble in methanol, ethanol and water, but can be dispersed in water.
XIAMETER PMX 1503 Fluid is Non-flammable, non-corrosive and is chemically stable.

Uses
XIAMETER PMX 1503 Fluid can be used as emulsifiers. China has provided that it can be applied during the fermentation process with the maximum usage amount being 0.2g/kg.
XIAMETER PMX 1503 Fluid can be used as advanced lubricants, anti-vibration oil, insulating oil, defoamers, release agents, polishes and vacuum diffusion pump oil.
XIAMETER PMX 1503 Fluid can be used as the paint for prevention of moisture and rust of metal surface.
XIAMETER PMX 1503 Fluid can also be used as the coating for the surfaces of buildings for prevention of water.
XIAMETER PMX 1503 Fluid is used as hardening polyurethane foams additive.
XIAMETER PMX 1503 Fluid can be used for applications such as: protective coatings for building materials, a cosmetic additive, a dielectric coolant, a lubricant and antiflatulent agent.
XIAMETER PMX 1503 Fluid can be used for a wide range of applications such as: heat transferring medium in chemical and petrochemical industries, a dielectric coolant, protective coatings for building materials, a cosmetic additive.

Production Methods
XIAMETER PMX 1503 Fluid are generally prepared from chlorosilanes.
The chlorosilanes are hydrolyzed to give hydroxyl compounds that condense to form elastomers.
Applications include electrical insulation, gaskets, surgical membranes and implants, and automobile engine components.

Synonyms
OCTAMETHYLTRISILOXANE
107-51-7
Trisiloxane, octamethyl-
1,1,1,3,3,5,5,5-Octamethyltrisiloxane
Dimeticone
dimethyl-bis(trimethylsilyloxy)silane
63148-62-9
Dimethicones
Dimethicone 350
Sentry Dimethicone
Pentamethyl(trimethylsilyloxy)disiloxane
CCRIS 3198
Dimethylbis(trimethylsiloxy)silane
EINECS 203-497-4
UNII-9G1ZW13R0G
9G1ZW13R0G
CHEBI:9147
DTXSID9040710
EC 203-497-4
Trisiloxane, 1,1,1,3,3,5,5,5-octamethyl-
MFCD00084411
MFCD00134211
MFCD00148360
dimeticonum
Dimeticona
FRD 20
Viscasil 5M
Ctamethyltrisiloxane
octamethyltrisiloxan-
MFCD00008264
Pentamethyl(trimethylsiloxy)disiloxane
Mirasil DM 20
octamethyl-trisiloxane
Dow Corning 1664
dimethicone macromolecule
Belsil DM 1000
VOLASIL DM-1
Dimeticonum [INN-Latin]
Dimethicone [USAN:BAN]
Dimeticona [INN-Spanish]
TRISILOXANE [INCI]
Octamethyltrisiloxane, 98%
Dimethicone 350 [USAN]
OS 20 (SILOXANE)
SCHEMBL23459
C8H24O2Si3
Siliconoil Pharma 100 cSt.
CCRIS 3957
Dow Corning High-Vacuum Grease
CHEMBL2142985
DTXCID7020710
CHEBI:31498
CXQXSVUQTKDNFP-UHFFFAOYSA-
HSDB 1808
C8-H24-O2-Si3
KF 96A1
OCTAMETHYLTRISILOXANE [MI]
dimethylbis(trimethylsiloxy)siliane
Dimethylbis(trimethylsilyloxy)silane
[(CH3)3SiO]2Si(CH3)2
Tox21_301002
CO9816
MFCD00165850
Silane, dimethylbis(trimethylsiloxy)-
AKOS015840180
Antifoam compound for anhydrous systems
CS-O-00804
DC 1664
FS-4459
LS-2478
NCGC00164100-01
NCGC00164100-02
NCGC00254904-01
CAS-107-51-7
LS-163457
FT-0631598
FT-0696355
O0257
O9816
C07261
D91850
S12475
A801717
J-001906
Q2013799
2,2,4,4,6,6-hexamethyl-3,5-dioxa-2,4,6-trisilaheptane
28349-86-2
XIAMETER PMX-0245
XIAMETER PMX-0245 is a volatile polydimethylcyclosiloxane composed mainly of cyclopentasiloxane.
XIAMETER PMX-0245 may be used in antiperspirants, deodorants, hair sprays, cleansing creams, skin creams, lotions and stick products, bath oils, suntan and shaving products, make-up and nail polishes.
XIAMETER PMX-0245 acts as a volatile carrier.

CAS: 541-02-6
MF: C10H30O5Si5
MW: 370.77
EINECS: 208-764-9

XIAMETER PMX-0245 is a low viscosity polydimethylcyclosiloxane composed mainly of cyclopentasiloxane.
XIAMETER PMX-0245 offers excellent spreading, easy rub-out, sensory enhancement, detackification, low surface tension and lubrication properties.
XIAMETER PMX-0245 imparts wet combing, detangling, reduced drying time, soft & silky feel to the skin and leaves no oily residue or build-up.
XIAMETER PMX-0245 is non-greasy, non-occlusive, non-stinging and is compatible with a wide range of cosmetic ingredients.

XIAMETER PMX-0245 is used alone or blended with other cosmetic fluids to provide a fluid base for a variety of cosmetic ingredients.
XIAMETER PMX-0245 finds application in formulating antiperspirants & deodorants, hair sprays, cleansing creams, skin creams, lotions, stick products, bath oils, sun-tan & shaving products, make-up and nail polishes.
XIAMETER PMX-0245 has a shelf life of 900 days.
XIAMETER PMX-0245 is Vegan suitable.

XIAMETER PMX-0245 is a volatile polydimethylcyclosiloxane composed mainly of cyclopentasiloxane.
XIAMETER PMX-0245 can be used as a volatile carrier fluid with excellent spreading, easy rub out, silky skin feel, and good compatibility with a wide range of cosmetic ingredients.
XIAMETER PMX-0245 is clear, tasteless, essentially odorless, non-greasy, and non-stinging.

XIAMETER PMX-0245 is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
XIAMETER PMX-0245 is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

XIAMETER PMX-0245 Chemical Properties
Melting point: -44°C
Boiling point: 90 °C/10 mmHg (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
Vapor pressure: 33.2Pa at 25℃
Refractive index: n20/D 1.396(lit.)
Fp: 162 °F
Storage temp.: 2-8°C
Solubility: <0.0001g/l (calculated)
Form: Liquid
Specific Gravity: 0.959
Color: Colorless
Explosive limit: 0.52-7%(V)
Water Solubility: Immiscible with water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,2848
BRN: 1800166
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: XMSXQFUHVRWGNA-UHFFFAOYSA-N
LogP: 8.07 at 24.6℃
CAS DataBase Reference: 541-02-6(CAS DataBase Reference)
NIST Chemistry Reference: XIAMETER PMX-0245 (541-02-6)
EPA Substance Registry System: XIAMETER PMX-0245 (541-02-6)

Uses
XIAMETER PMX-0245 used in cosmetic and personal care products.
Used in dermal exposure and inhalation toxicity study.
Intermediate in the manufacture of high mol wt siloxane polymers.
Carrier ingredient in personal care products; dry cleaning solvent.
XIAMETER PMX-0245 is incorporated into a formulation for its emollient and solvent activity.
XIAMETER PMX-0245 and decamethylcyclopentasiloxane are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.

Synonyms
DECAMETHYLCYCLOPENTASILOXANE
541-02-6
Cyclopentasiloxane, decamethyl-
Cyclomethicone 5
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Dimethylsiloxane pentamer
Dekamethylcyklopentasiloxan
NUC silicone VS 7158
Dow corning 345
CYCLOMETHICONE
Silicon SF 1202
Cyclic dimethylsiloxane pentamer
Ciclopentasiloxane
Cyclomethicone D5
KF 995
VS 7158
CCRIS 1328
HSDB 5683
Dekamethylcyklopentasiloxan [Czech]
EINECS 208-764-9
UNII-0THT5PCI0R
0THT5PCI0R
SF 1202
BRN 1800166
C10H30O5Si5
DTXSID1027184
D5
EC 208-764-9
4-04-00-04128 (Beilstein Handbook Reference)
Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-
MFCD00046966
2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane
D5-sil
Ddecamethylcyclopentasiloxane
decamethyl cyclopentasiloxane
D5 Cyclomethicone
dimethylcyclopentasiloxane
Decamethylcylopentasiloxane
JEESILC CPS-211
SCHEMBL28497
N-Propylheptamethyltrisiloxane
XIAMETER PMX-0245
DTXCID907184
CYCLOPENTASILOXANE (D5)
2,2,4,4,6,6,8,8,10,10-Decamethylcyclopentasiloxane
CHEMBL1885178
CYCLOPENTASILOXANE [INCI]
D5 (Decamethylcyclopentasiloxane)
CHEBI:191092
Decamethylcyclopentasiloxane, 97%
C10-H30-O5-Si5
CYCLOMETHICONE 5 [USP-RS]
CYCLOMETHICONE 5 [WHO-DD]
BCP15826
Tox21_303170
CD3770
KF-995
AKOS008901199
CS-O-01236
CS-W009767
DB11244
DOW CORNING ST CYCLOMETHICONE 5
DECAMETHYLCYCLOPENTASILOXANE [MI]
NCGC00163981-01
NCGC00257224-01
OCTAMETHYLCYCLOTETRASILOXANE (D5)
AS-59731
CAS-541-02-6
DECAMETHYLCYCLOPENTASILOXANE [HSDB]
LS-58254
KP-545 COMPONENT CYCLOMETHICONE 5
D1890
D3770
Decamethylcyclopentasiloxane (cyclic monomer)
FT-0665531
D78203
S05475
Decamethylcyclopentasiloxane, analytical standard
Q414350
Ciclopentasiloxano, 2,2,4,4,6,6,8,8,10,10-decametil-
decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #
D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material
XIAMETER PMX-0246

Product Code: FX165205
CAS Number: 63148-52-7
Appearance: Colourless liquid
Viscosity: 475 to 525cSt

CAS No.: 540-97-6
Molecular Weight:444.92364
Modify Date.: 2022-11-07 06:17
XIAMETER PMX-0246 used in cosmetic and personal care products.
XIAMETER PMX-0246 is used in dermal exposure and inhalation toxicity study.

XIAMETER PMX-0246 is a volatile polydimethylcyclosiloxane composed mainly of cyclohexasiloxane.
XIAMETER PMX-0246 is a base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics.
XIAMETER PMX-0246 can be used in antiperspirants, skin creams, lotions and stick products, bath oils, makeup, suntan and shaving products.

XIAMETER PMX-0246 by Dow is a non-greasy, non-occlusive, volatile carrier.
XIAMETER PMX-0246 is a blend of polydimethylcyclosiloxane composed of cyclotetrasiloxane and cyclopentasiloxane.
XIAMETER PMX-0246 offers excellent spreading, sensory enhancement, detackification, low surface tension, quick absorption, increased glide and lubrication properties.
XIAMETER PMX-0246 imparts a soft & silky feel to the skin and leaves no oily residue or build-up.
XIAMETER PMX-0246 is compatible with sunscreens and a wide range of cosmetic ingredients.
XIAMETER PMX-0246 provides wet combing, reduced greasiness and drying time.
In cleansing products, XIAMETER PMX-0246 lifts and removes dirt without a stinging sensation.
XIAMETER PMX-0246 finds application in formulating antiperspirants, make-up, skin creams, lotions, stick products, bath oils, sun-tan and shaving products.
The shelf life of the product is 900 days.
XIAMETER PMX-0246 is Vegan suitable.

A volatile, low viscosity cyclohexasiloxane fluid for use in skincare, suncare, color cosmetics, hair care, and antiperspirant / deodorant applications.
INCI Name: Cyclohexasiloxane (and) Cyclopentasiloxane

Uses of XIAMETER PMX-0246
Antiperspirants
Skin creams
Lotions and stick products
Bath oils
Suntan and shaving products
Make-up
In cleansing products, lifts and removes dirt without a stinging sensation
Benefits
Volatile carrier
Compatible with a wide range of cosmetic ingredients
Low surface tension
Imparts silky feel to the skin
Excellent spreading
Leaves no oily residue or build up
Detackification
Non-greasy
Does not contain ingredients of animal origin (Suitable for Vegan)
No animal cross contamination
No porcine contamination

XIAMETER PMX-0246 silicone fluid is a type of silicone oil with a viscosity of 500cSt.
XIAMETER PMX-0246 has been shown to be efficient in vaporization and absorption, with vapor pressure of 0.1mmHg at 25°C.
Xiameter PMX-200 silicone fluid is used for the removal of organic vapors from an area by adsorption onto the surface of the liquid, which is then heated to release the vapors as gas.
This product has a cyclic efficiency that can be increased by adding activated carbon or other absorbers to increase its capacity for desorption.

FEATURES of XIAMETER PMX-0246
Volatile carrier
Compatible with a wide range of cosmetic ingredients
Low surface tension

BENEFITS of XIAMETER PMX-0246
Imparts silky feel to the skin
Excellent spreading
Leaves no oily residue or build up
Detackification
Non-greasy

APPLICATIONS of XIAMETER PMX-0246
A base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics.
Can be used in antiperspirants, skin creams, lotions and stick products, bath oils, suntan and shaving products, make-up.
In cleansing products XIAMETER PMX-0246 Cyclohexasiloxane lifts and removes dirt without a stinging sensation.

TYPICAL PROPERTIES of XIAMETER PMX-0246
Specification Writers: These values are not intended for use in preparing specifications.
Appearance: Colorless liquid
Specific gravity at 25°C (77°F): 0.96
Viscosity at 25°C (77°F) mm2:6.8
Refractive index at 25°C (77°F): 1.402
Surface tension at 25°C (77°F) mN/m: 18.8
Flash point – closed cup °C (°F): 93 (199)
Freeze point °C (°F): <-40 (<-40)
Boiling point at 760mm Hg °C (°F): 245 (473)
Water content ppm: 250
Cyclotetrasiloxane (D4) content: % <0.5

DESCRIPTION of XIAMETER PMX-0246
XIAMETER PMX-0246 Cyclohexasiloxane is a blend of volatile polydimethylcyclosiloxane composed of cyclotetrasiloxane and cyclopentasiloxane.

HOW TO USE XIAMETER PMX-0246
Cyclohexasiloxane may be used alone or blended with other cosmetic fluids to provide a fluid base for a variety of cosmetic ingredients.

STORAGE of XIAMETER PMX-0246
Product should be stored at or below 25°C (77°F) in original, unopened containers.
The most up-to-date shelf life information can be found on the XIAMETER Web site in the

Product Details of XIAMETER PMX-0246
Grade: Technical
Appearance: liquid
Boiling Point: 245 °C (473 °F)
This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Color: colorless
Flash Point: 100 °C (212 °F)
Kinematic Viscosity: 6.8 mm2/s @ 25 °C (77 °F)
Odor: odorless
Relative Density: 0.96 Reference Material: (water = 1)

Physical Properties of XIAMETER PMX-0246
Specific Gravity: 0.960 g/cc
@Temperature 25.0 °C
0.960 g/cc
@Temperature 77.0 °F
Viscosity Measure: 6.8 cSt
Kinetic/Kinematic
Surface Tension: 18.8 dynes/cm

Thermal Properties of XIAMETER PMX-0246
Melting Point: <= -40.0 °C
Boiling Point: 245 °C
Flash Point: 93.0 °C
199 °F

Optical Properties of XIAMETER PMX-0246
Refractive Index: 1.402

Processing Properties
Moisture Content: 0.025 %
0.025 %
Shelf Life: 30.0 Month
30.0 Month

Features & Benefits of XIAMETER PMX-0246
Volatile carrier
Compatible with a wide range of cosmetic ingredients
Low surface tension
Imparts silky feel to the skin
Excellent spreading
Leaves no oily residue or build up
Detackification
Non-greasy

Applications of XIAMETER PMX-0246
A base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics.
Can be used in antiperspirants, skin creams, lotions and stick products, bath oils, suntan and shaving products, make-up.
In cleansing products XIAMETER™ PMX-0246 Cyclohexasiloxane lifts and removes dirt without a stinging sensation

Typical Properties of XIAMETER PMX-0246
Appearance: Colorless liquid
Specific gravity at 25°C (77°F): 0.96
Viscosity at 25°C (77°F) mm2.s-1: 6.8
Refractive index at 25°C (77°F): 1.402
Surface tension at 25°C (77°F) mN/m: 18.8
Flash point – closed cup °C (°F): 93 (199)
Freeze point °C (°F): < -40 (< -40)
Boiling point at 760 mm Hg °C (°F): 245 (473)
Water content ppm : 250
Cyclotetrasiloxane (D4) content: % < 0.1

Description
XIAMETER PMX-0246 Cyclohexasiloxane is a blend of volatile polydimethylcyclosiloxane composed of cyclopentasiloxane and cyclohexasiloxane.

Handling of XIAMETER PMX-0246
Care should be taken when handling volatile fluids at temperatures 10°C (508°F) below the quoted flash point.
As with any flammable material, containers should be kept tightly closed and away from heat, sparks, open flames and other sources of ignition.

Usable Life and Storage
Product should be stored at or below 25°C (77°F) in original, unopened containers.
Limitations This product is neither tested nor represented as suitable for medical or pharmaceutical uses.

Health And Environmental Information
To support customers in their product safety needs, Dow has an extensive Product Stewardship organization and a team of product safety and regulatory compliance specialists available in each area.

Catalogue number: PA ENV 000453
Chemical name: Dodecamethylcyclohexasiloxane
CAS Number: 540-97-6
Synonyms:2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane; Cyclohexasiloxane, dodecamethyl; 2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane; Cyclohexadimethylsiloxane; Dodecamethylcyclohexasiloxane; Hexadecamethylcyclohexasiloxane; Xiameter PMX 0246;
Molecular form: C12H36O6Si6
Appearance: NA
Mol. Weight:444.92
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient

Safety and Handling of XIAMETER PMX-0246
Risk Statements: R36/37/38
Safety Statements: 26-36/37/39
Octanol/Water Partition Coefficient: log Kow = 6.33 (est)

DisposalMethods
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

Formulations/Preparations
Typically including dodecamethylcyclohexasiloxane (D6) with a general formula of (-Si(CH3)2O-)x in a cyclic configuration, where x is generally less than 8, and more commonly x is 3-7.
This formulation is commonly used in cosmetics.

Specification
XIAMETER PMX-0246, with the cas register number 540-97-6, has other name of Cyclohexasiloxane,2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-.
And its product categories are including organics; si (classes of silicon compounds); siloxanes; si-o compounds.
This chemical is usually used to prepare silicone oil and silicon rubber, with the form of mixed cyclic siloxane.

Computed Properties Of XIAMETER PMX-0246
Molecular Weight: 444.92
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 444.11274807
Monoisotopic Mass: 444.11274807
Topological Polar Surface Area: 55.4 Ų
Heavy Atom Count: 24
Formal Charge: 0
Complexity: 320
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Xiameter PMX-200 is a polysiloxanes fluid with high dielectric strength and damping action.
The silicone fluid is also chemical and water-resistant making it ideal for a range of industrial applications.
Available in different viscosities from 5-500 CS and in different pack sizes including drums and pails.

Xiameter PMX-200 Applications
Wide range of applications including use as a cosmetic ingredient, elastomer and plastics lubricant, electrical insulating fluid, foam preventive or breaker, mechanical fluid, mould release agent, surface active agent, and solvent-based finishing and fatliquoring of leather.
Automotive applications include exterior wax, conditioner and sealant to enhance shine and durability.

Xiameter PMX-200 Features
Ease of application
Ease of buffing
Enhances colour
High water repellency
High compressibility
High shearability without breakdown
High spreadability and compatibility
Low environmental hazard
Low fire hazard
Low reactivity and vapour pressure
Low surface energy
Good heat stability
Essentially odourless, tasteless and nontoxic
Soluble in a wide range of solvents

Product Information of XIAMETER PMX-0246
XIAMETER PMX-0246 Silicone Fluid may be used alone or blended with other cosmetic fluids to provide a fluid base for a variety of cosmetic ingredients.
XIAMETER PMX-0246 features good solubility in most anhydrous alcohols and in many solvents used in cosmetics.
This version of PMX-200 is 5cs (centi-stoke) viscosity.

Features of XIAMETER PMX-0246:
Good dielectric properties
High water repellency
High shearability without breakdown
High compressibility
High spreadability
Low surface tension
Low fire hazard and reactivity
Low vapor pressure
Good heat stability
Good leveling and easy rubout
Non volatile carrier
Little change in physical properties over a wide temperature span – a relatively flat viscosity-temperature slope, and serviceability from -40°C up to 200°C
Low surface tension – readily wets clean surfaces to impart water repellency and release characteristics

Applications:
Personal care products such as antiperspirants, deodorants, hair sprays, cleansing creams, skin creams, lotions, bath oils, suntan products, nail polishes
Industrial applications such as glass vial and lens coatings, household product ingredients, mechanical fluids, penetrating oil ingredients, surface active agents, coatings, electrical insulating fluids and polish ingredients

Synonyms of XIAMETER PMX-0246
540-97-6
208-762-8
CYCLOHEXASILOXANE
CYCLOHEXASILOXANE [INCI]
CYCLOMETHICONE 6 [USP-RS]
D-6
D6
DODECAMETHYLCYCLOHEXASILOXANE
DODECAMETHYLCYCLOHEXASILOXANE [HSDB]
DODECAMETHYLCYCLOHEXASILOXANE [MI]
DODECAMETHYLCYCLOHEXASILOXANE [WHO-DD]
XIAMETER PMX-0246
Synonyms
DODECAMETHYLCYCLOHEXASILOXANE
540-97-6
Cyclohexasiloxane, dodecamethyl-
Cyclomethicone 6
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexasilacyclododecane
Cyclohexasiloxane
XHK3U310BA
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane
EINECS 208-762-8
UNII-XHK3U310BA
HSDB 7723
EC 208-762-8
dodecamethyl cyclohexasiloxane
SCHEMBL93785
XIAMETER PMX-0246
CYCLOHEXASILOXANE [INCI]
DTXSID6027183
IUMSDRXLFWAGNT-UHFFFAOYSA-
CHEBI:191103
CYCLOMETHICONE 6 [USP-RS]
MFCD00144215
AKOS015839990
ZINC169794506
FS-5671
DODECAMETHYLCYCLOHEXASILOXANE [MI]
DODECAMETHYLCYCLOHEXASILOXANE [HSDB]
DB-00858
D2040
DODECAMETHYLCYCLOHEXASILOXANE [WHO-DD]
FT-0625566
S08515
T71035
Dodecamethylcyclohexasiloxane, analytical standard
A914553
Q27293843
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane #
Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, 95%
2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane, AldrichCPR
Cyclomethicone 6, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-1,3,5,7,9,11-hexaoxa-2,4,6,8,10,12-hexa
D-6
XIAMETER PMX-0246
XIAMETER PMX-0246 is a volatile polydimethylcyclosiloxane composed mainly of cyclohexasiloxane.
XIAMETER PMX-0246 is a base fluid in a number of personal care products, with excellent spreading and lubrication properties and unique volatility characteristics.
XIAMETER PMX-0246 can be used in antiperspirants, skin creams, lotions and stick products, bath oils, makeup, suntan and shaving products.

CAS: 541-02-6
MF: C10H30O5Si5
MW: 370.77
EINECS: 208-764-9

XIAMETER PMX-0246, also known as D5 and D5, is an organosilicon compound with the formula [(CH3)2SiO]5.
XIAMETER PMX-0246 is a colorless and odorless liquid that is slightly volatile.
XIAMETER PMX-0246 Cyclohexasiloxane by Dow is a non-greasy, non-occlusive, volatile carrier.
XIAMETER PMX-0246 is a blend of polydimethylcyclosiloxane composed of cyclotetrasiloxane and cyclopentasiloxane.
XIAMETER PMX-0246 offers excellent spreading, sensory enhancement, detackification, low surface tension, quick absorption, increased glide and lubrication properties.
XIAMETER PMX-0246 imparts a soft & silky feel to the skin and leaves no oily residue or build-up.
XIAMETER PMX-0246 is compatible with sunscreens and a wide range of cosmetic ingredients.
XIAMETER PMX-0246 provides wet combing, reduced greasiness and drying time.
In cleansing products, XIAMETER PMX-0246 lifts and removes dirt without a stinging sensation.
XIAMETER PMX-0246 finds application in formulating antiperspirants, make-up, skin creams, lotions, stick products, bath oils, sun-tan and shaving products.
The shelf life of the product is 900 days.
XIAMETER PMX-0246 is Vegan suitable.

XIAMETER PMX-0246 is an organosilicon compound.
XIAMETER PMX-0246is a cyclic siloxane, that has a silicon-oxygen bond in a cyclic arrangement and methyl groups attached with the silicon atom.
XIAMETER PMX-0246 is used in the production of some silicon-based polymers that are widely used in various personal care products.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

XIAMETER PMX-0246 Chemical Properties
Melting point: -44°C
Boiling point: 90 °C/10 mmHg (lit.)
Density: 0.958 g/mL at 25 °C (lit.)
Vapor pressure: 33.2Pa at 25℃
Refractive index: n20/D 1.396(lit.)
Fp: 162 °F
Storage temp.: 2-8°C
Solubility: <0.0001g/l (calculated)
Form: Liquid
Specific Gravity: 0.959
Color: Colorless
Explosive limit 0.52-7%(V)
Water Solubility: Immiscible with water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
Merck: 14,2848
BRN: 1800166
Stability: Stable. Incompatible with strong oxidizing agents.
InChIKey: XMSXQFUHVRWGNA-UHFFFAOYSA-N
LogP: 8.07 at 24.6℃
CAS DataBase Reference: 541-02-6(CAS DataBase Reference)
NIST Chemistry Reference: XIAMETER PMX-0246(541-02-6)
EPA Substance Registry System: XIAMETER PMX-0246 (541-02-6)

Uses
A cyclic volatile methylsiloxane (cVMS) used in cosmetic and personal care products.
Used in dermal exposure and inhalation toxicity study.
Intermediate in the manufacture of high mol wt siloxane polymers.
Carrier ingredient in personal care products; dry cleaning solvent.
XIAMETER PMX-0246 is incorporated into a formulation for its emollient and solvent activity.
Octamethylcyclotetrasiloxane and XIAMETER PMX-0246 are major industrial products, which are either marketed as such or used for the production of polydimethylsiloxanes.

XIAMETER PMX-0246 is classified as a cyclomethicone.
Such fluids are commonly used in cosmetics, such as deodorants, sunblocks, hair sprays and skin care products.
XIAMETER PMX-0246 is becoming more common in hair conditioners, as it makes the hair easier to brush without breakage.
XIAMETER PMX-0246 is also used as part of silicone-based personal lubricants.
XIAMETER PMX-0246 is considered an emollient.
In Canada, among the volume used in consumer products approximately 70% were for antiperspirants and 20% for hair care products.
10,000–100,000 tonnes per year of XIAMETER PMX-0246 is manufactured and/or imported in the European Economic Area.
Atmospheric emissions of XIAMETER PMX-0246 in the Northern Hemisphere were estimated to 30,000 tonnes per year.

Production and Polymerization
Commercially XIAMETER PMX-0246 is produced from dimethyldichlorosilane.
Hydrolysis of the dichloride produces a mixture of cyclic dimethylsiloxanes and polydimethylsiloxane.
From this mixture, the cyclic siloxanes including XIAMETER PMX-0246 can be removed by distillation.
In the presence of a strong base such as KOH, the polymer/ring mixture is equilibrated, allowing complete conversion to the more volatile cyclic siloxanes:

[(CH3)2SiO]5n → n [(CH3)2SiO]5
where n is a positive integer.
XIAMETER PMX-0246 are also precursors to the polymer.
The catalyst is again KOH.

Synonyms
DECAMETHYLCYCLOPENTASILOXANE
541-02-6
Cyclopentasiloxane, decamethyl-
Cyclomethicone 5
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Dimethylsiloxane pentamer
Dekamethylcyklopentasiloxan
NUC silicone VS 7158
Cyclic dimethylsiloxane pentamer
Ciclopentasiloxane
Cyclomethicone D5
KF 995
VS 7158
0THT5PCI0R
DTXSID1027184
D5
Dow corning 345
Silicon SF 1202
Cyclopentasiloxane, 2,2,4,4,6,6,8,8,10,10-decamethyl-
MFCD00046966
2,2,4,4,6,6,8,8,10,10-decamethyl-1,3,5,7,9,2,4,6,8,10-pentoxapentasilecane
D5-sil
CCRIS 1328
HSDB 5683
Dekamethylcyklopentasiloxan [Czech]
EINECS 208-764-9
UNII-0THT5PCI0R
Ddecamethylcyclopentasiloxane
decamethyl cyclopentasiloxane
SF 1202
BRN 1800166
C10H30O5Si5
D5 Cyclomethicone
dimethylcyclopentasiloxane
Decamethylcylopentasiloxane
JEESILC CPS-211
EC 208-764-9
SCHEMBL28497
N-Propylheptamethyltrisiloxane
XIAMETER PMX-0245
4-04-00-04128 (Beilstein Handbook Reference)
DTXCID907184
CYCLOPENTASILOXANE (D5)
2,2,4,4,6,6,8,8,10,10-Decamethylcyclopentasiloxane
CHEMBL1885178
CYCLOPENTASILOXANE [INCI]
CHEBI:191092
Decamethylcyclopentasiloxane, 97%
XMSXQFUHVRWGNA-UHFFFAOYSA-N
CYCLOMETHICONE 5 [USP-RS]
CYCLOMETHICONE 5 [WHO-DD]
BCP15826
Tox21_303170
CD3770
KF-995
AKOS008901199
CS-W009767
DB11244
DOW CORNING ST CYCLOMETHICONE 5
DECAMETHYLCYCLOPENTASILOXANE [MI]
NCGC00163981-01
NCGC00257224-01
OCTAMETHYLCYCLOTETRASILOXANE (D5)
AS-59731
CAS-541-02-6
DECAMETHYLCYCLOPENTASILOXANE [HSDB]
KP-545 COMPONENT CYCLOMETHICONE 5
D1890
D3770
Decamethylcyclopentasiloxane (cyclic monomer)
FT-0665531
D78203
S05475
Decamethylcyclopentasiloxane, analytical standard
Q414350
decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane
Cyclomethicone 5, United States Pharmacopeia (USP) Reference Standard
2,2,4,4,6,6,8,8,10,10-Decamethyl-1,3,5,7,9,2,4,6,8,10-pentaoxapentasilecane #
D5 Cyclomethicone, Pharmaceutical Secondary Standard; Certified Reference Material
XYLENE
Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen) (from Greek ξύλο, xylo, "wood"), xylol or dimethylbenzene is any one of three isomers of dimethylbenzene, or a combination thereof. With the formula (CH3)2C6H4, each of the three compounds has a central benzene ring with two methyl groups attached at substituents. They are all colorless, flammable liquids, some of which are of great industrial value. The mixture is referred to as both Xylene (FIRIN TİNER, Ksilen) and, more precisely, Xylene (FIRIN TİNER, Ksilen)s. Occurrence and production of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen)s are an important petrochemical produced by catalytic reforming and also by coal carbonisation in the manufacture of coke fuel. They also occur in crude oil in concentrations of about 0.5–1%, depending on the source. Small quantities occur in gasoline and aircraft fuels. Xylene (FIRIN TİNER, Ksilen)s are produced mainly as part of the BTX aromatics (benzene, toluene, and Xylene (FIRIN TİNER, Ksilen)s) extracted from the product of catalytic reforming known as reformate. The Xylene (FIRIN TİNER, Ksilen) mixture is a slightly greasy, colorless liquid commonly encountered as a solvent. Several million tons are produced annually.[1] In 2011, a global consortium began construction of one of the world's largest Xylene (FIRIN TİNER, Ksilen) plants in Singapore.[2] History of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen) was first isolated and named in 1850 by the French chemist Auguste Cahours (1813–1891), having been discovered as a constituent of wood tar. Isomers of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen) exists in three isomeric forms. The isomers can be distinguished by the designations ortho- (o-), meta- (m-) and para- (p-), which specify to which carbon atoms (of the benzene ring) the two methyl groups are attached. By counting the carbon atoms around the ring starting from one of the ring carbons bonded to a methyl group, and counting towards the second methyl group, the o-isomer has the IUPAC name of 1,2-dimethylbenzene, the m-isomer is 1,3-dimethylbenzene and the p-isomer is 1,4-dimethylbenzene. Of the three isomers, the p-isomer is the most industrially sought after since it can be oxidized to terephthalic acid.[1] Industrial production of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen)s are produced by the methylation of toluene and benzene.[1][4] Commercial or laboratory-grade Xylene (FIRIN TİNER, Ksilen) produced usually contains about 40-65% of m-Xylene (FIRIN TİNER, Ksilen) and up to 20% each of o-Xylene (FIRIN TİNER, Ksilen), p-Xylene (FIRIN TİNER, Ksilen) and ethylbenzene.[5][6][7] The ratio of isomers can be shifted to favor the highly valued p-Xylene (FIRIN TİNER, Ksilen) via the patented UOP-Isomar process[8] or by transalkylation of Xylene (FIRIN TİNER, Ksilen) with itself or trimethylbenzene. These conversions are catalyzed by zeolites. ZSM-5 is used to facilitate some isomerization reactions leading to mass production of modern plastics. Properties of Xylene (FIRIN TİNER, Ksilen) The chemical and physical properties of Xylene (FIRIN TİNER, Ksilen) differ according to the respective isomers. The melting point ranges from −47.87 °C (−54.17 °F) (m-Xylene (FIRIN TİNER, Ksilen)) to 13.26 °C (55.87 °F) (p-Xylene (FIRIN TİNER, Ksilen))—as usual, the para isomer's melting point is much higher because it packs more readily in the crystal structure. The boiling point for each isomer is around 140 °C (284 °F). The density of each isomer is around 0.87 g/mL (7.26 lb/U.S. gallon or 8.72 lb/imp gallon) and thus is less dense than water. Xylene (FIRIN TİNER, Ksilen) in air can be smelled at concentrations as low as 0.08 to 3.7 ppm (parts of Xylene (FIRIN TİNER, Ksilen) per million parts of air) and can be tasted in water at 0.53 to 1.8 ppm. Xylene (FIRIN TİNER, Ksilen)s form azeotropes with water and a variety of alcohols. With water the azeotrope consists of 60% Xylene (FIRIN TİNER, Ksilen)s and boils at 94.5 °C.[1] As with many alkylbenzene compounds, Xylene (FIRIN TİNER, Ksilen)s form complexes with various halocarbons.[10] The complexes of different isomers often have dramatically different properties from each other.[11] Applications of Xylene (FIRIN TİNER, Ksilen) Terephthalic acid and related derivatives p-Xylene (FIRIN TİNER, Ksilen) is the principal precursor to terephthalic acid and dimethyl terephthalate, both monomers used in the production of polyethylene terephthalate (PET) plastic bottles and polyester clothing. 98% of p-Xylene (FIRIN TİNER, Ksilen) production, and half of all Xylene (FIRIN TİNER, Ksilen)s produced is consumed in this manner.[7][12] o-Xylene (FIRIN TİNER, Ksilen) is an important precursor to phthalic anhydride. The demand for isophthalic acid is relatively modest so m-Xylene (FIRIN TİNER, Ksilen) is rarely sought (and hence the utility of its conversion to the o- and p-isomers). Solvent applications and industrial purposes of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen) is used as a solvent. In this application, with a mixture of isomers, it is often referred to as Xylene (FIRIN TİNER, Ksilen)s or xylol. Solvent Xylene (FIRIN TİNER, Ksilen) often contains a small percentage of ethylbenzene. Like the individual isomers, the mixture is colorless, sweet-smelling, and highly flammable. Areas of application include the printing, rubber, and leather industries. It is a common component of ink, rubber, and adhesives.[13] In thinning paints and varnishes, it can be substituted for toluene where slower drying is desired, and thus is used by conservators of art objects in solubility testing.[14] Similarly it is a cleaning agent, e.g., for steel, silicon wafers, and integrated circuits. In dentistry, Xylene (FIRIN TİNER, Ksilen) can be used to dissolve gutta percha, a material used for endodontics (root canal treatments). In the petroleum industry, Xylene (FIRIN TİNER, Ksilen) is also a frequent component of paraffin solvents, used when the tubing becomes clogged with paraffin wax. For similar reasons, it is often the active ingredient in commercial products for ear wax (cerumen) removal.(1) Laboratory use of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen) is used in the laboratory to make baths with dry ice to cool reaction vessels,[15] and as a solvent to remove synthetic immersion oil from the microscope objective in light microscopy.[16] In histology, Xylene (FIRIN TİNER, Ksilen) is the most widely used clearing agent.[17] Xylene (FIRIN TİNER, Ksilen) is used to remove paraffin from dried microscope slides prior to staining. After staining, microscope slides are put in Xylene (FIRIN TİNER, Ksilen) prior to mounting with a coverslip. Precursor to other compounds of Xylene (FIRIN TİNER, Ksilen) Although conversion to terephthalic acid is the dominant chemical conversion, Xylene (FIRIN TİNER, Ksilen)s are precursors to other chemical compounds. For instance chlorination of both methyl groups gives the corresponding Xylene (FIRIN TİNER, Ksilen) dichlorides (bis(chloromethyl)benzenes) whilst mono-bromination yields xylyl bromide, a tear gas agent used in World War I. Health and safety of Xylene (FIRIN TİNER, Ksilen) Xylene (FIRIN TİNER, Ksilen) is flammable but of modest acute toxicity, with LD50 ranges from 200 to 5000 mg/kg for animals. Oral LD50 for rats is 4300 mg/kg. The principal mechanism of detoxification is oxidation to methylbenzoic acid and hydroxylation to hydroXylene (FIRIN TİNER, Ksilen).[1] The main effect of inhaling Xylene (FIRIN TİNER, Ksilen) vapor is depression of the central nervous system (CNS), with symptoms such as headache, dizziness, nausea and vomiting. At an exposure of 100 ppm, one may experience nausea or a headache. At an exposure between 200 and 500 ppm, symptoms can include feeling "high", dizziness, weakness, irritability, vomiting, and slowed reaction time.[18][19] The side effects of exposure to low concentrations of Xylene (FIRIN TİNER, Ksilen) (< 200 ppm) are reversible and do not cause permanent damage. Long-term exposure may lead to headaches, irritability, depression, insomnia, agitation, extreme tiredness, tremors, hearing loss, impaired concentration and short-term memory loss.[20][clarification needed] A condition called chronic solvent-induced encephalopathy, commonly known as "organic solvent syndrome" has been associated with Xylene (FIRIN TİNER, Ksilen) exposure. There is very little information available that isolates Xylene (FIRIN TİNER, Ksilen) from other solvent exposures in the examination of these effects. Hearing disorders have been also linked to Xylene (FIRIN TİNER, Ksilen) exposure, both from studies with experimental animals,[21][22] as well as clinical studies. Xylene (FIRIN TİNER, Ksilen) is also a skin irritant and strips the skin of its oils, making it more permeable to other chemicals. The use of impervious gloves and masks, along with respirators where appropriate, is recommended to avoid occupational health issues from Xylene (FIRIN TİNER, Ksilen) exposure.[18] Xylene (FIRIN TİNER, Ksilen)s are metabolized to methylhippuric acids.[26][27] The presence of methylhippuric acid can be used as a biomarker to determine exposure to Xylene (FIRIN TİNER, Ksilen). p-Xylene (FIRIN TİNER, Ksilen) and m-Xylene (FIRIN TİNER, Ksilen) cannot be separated by distillation because their boiling points are too close. In rats and mice, m- and p-Xylene (FIRIN TİNER, Ksilen) are distributed primarily to lipid-rich tissues, such as fat, blood, and brain and also in organs highly perfused with blood such as kidney and liver. Small amounts of p-Xylene (FIRIN TİNER, Ksilen) and o-Xylene (FIRIN TİNER, Ksilen) cross the placenta and distribute to amnionic fluid and fetal tissue. Oral administration of m-Xylene (FIRIN TİNER, Ksilen) to rats led to distribution of 14C-m-Xylene (FIRIN TİNER, Ksilen) in adipose tissue, approximately 0.3% of dose in female and 0.1% in males. Humans exposed to 46 or 92 ppm of o-, m-, p-Xylene (FIRIN TİNER, Ksilen) or a mixture (1:1:1) of the three for 8 hr absorbed approx 64% of the inhaled Xylene (FIRIN TİNER, Ksilen). No difference in the absorption rate was reported due to level of exposure, length of exposure, or the type and/or mixture of the Xylene (FIRIN TİNER, Ksilen) isomers. The absorption of Xylene (FIRIN TİNER, Ksilen) appeared to vary among individuals due to differences in ventilation rate. ... Individuals with an incr ventilation rate retained less Xylene (FIRIN TİNER, Ksilen). Metab of p-Xylene (FIRIN TİNER, Ksilen) (100 umol) studied in isolated, perfused rabbit livers and lungs. Release of p-tolualdehyde into circulation did not occur in perfused rabbit livers. P-toluric acid (n-p-toluylglycine) was major hepatic metabolite, with smaller amt of toluic acid & p-methylbenzyl alcohol. Rabbit livers did not produce detectable amt of p-tolualdehyde, 2,5-dimethylphenol or any glucuronide conjugates. One major pulmonary metab was p-methylbenzyl alc. Predominance of this metab reflects deficiency of lung tissue in alc dehydrogenase. Perfused lung also produced 2,5-dimethylphenol a derivative not produced in the liver. During p-Xylene (FIRIN TİNER, Ksilen) metab in perfused lungs, derivatives which became covalently bound to lung proteins were formed which suggests that p-Xylene (FIRIN TİNER, Ksilen) metab might proceed at least partially through reactive intermediate(s) causing destruction of pulmonary cytochrome P450. The involvement of sequential side-chain oxidn, sulfation, & glutathione conjugation in formation of mercapturic acids from Xylene (FIRIN TİNER, Ksilen)s was investigated. The position of methyl groups attached to the aromatic nucleus affected metabolism. Factors that are involved in high yield of mercapturic acids after admin of o-Xylene (FIRIN TİNER, Ksilen) as compared to m-Xylene (FIRIN TİNER, Ksilen) & p-Xylene (FIRIN TİNER, Ksilen) incl relatively low apparent affinity of o-methylbenzyl alcohol for cytosolic alcohol dehydrogenase, the relatively high apparent affinity of o-methylbenzyl alc for cytosolic sulfotransferase, & the high electrophilic reactivity of the o-methylbenzyl sulfate. In rats, guinea pigs, and rabbits, all three isomers /ortho-, meta-, and para-Xylene (FIRIN TİNER, Ksilen)/ are oxidized on the methyl group to form the corresponding toluic acid or on the ring to form phenols. There was no evidence that both methyl groups were oxidized; unconjugated 3,5-dimethylphenol and its glucuronide were isolated from urine. In rats exposed to atmospheres of m-Xylene (FIRIN TİNER, Ksilen) and ethylbenzene, methylhippuric acid, dimethylphenol, and methylbenzene alcohol were identified in urine as metabolites of m-Xylene (FIRIN TİNER, Ksilen). Xylene (FIRIN TİNER, Ksilen)s are metabolized primarily by oxidation to the methylbenzyl alcohols, followed by further oxidation to the corresponding methylbenzoic acids (toluic acids). These can be conjugated with glycine to form methylhippurates, or with UDPglucuronate to form acyl glucuronides. ... Xylene (FIRIN TİNER, Ksilen)s are metabolized in humans primarily to the corresponding methylhippuric acid (toluric acid); and glycine conjugation is considered to be a rate-limiting step. Only a small portion is excreted as dimethylphenol: 2,3-dimethylphenol and 3,4-dimethylphenol after exposure to ortho-Xylene (FIRIN TİNER, Ksilen), 2,4-dimethylphenol after exposure to meta-Xylene (FIRIN TİNER, Ksilen) and 2,5-dimethylphenol after exposure to para-Xylene (FIRIN TİNER, Ksilen). All three isomers of Xylene (FIRIN TİNER, Ksilen) are primarily metabolized by oxidation of a methyl group and conjugation with glycine to yield the methylhippuric acid. In humans exposed to Xylene (FIRIN TİNER, Ksilen), >90% of the absorbed Xylene (FIRIN TİNER, Ksilen) is excreted in the urine as the methylhippuric acid. Aromatic hydroxylation of Xylene (FIRIN TİNER, Ksilen) to xylenol occurs to only a limited extent in humans. Less than 2% of an absorbed dose is excreted in the urine as xylenol. Other minor metabolites found in urine include methylbenzyl alcohol and glucuronic acid conjugates of the oxidized Xylene (FIRIN TİNER, Ksilen). Metabolism in animals is qualitatively similar, but glucuronide conjugates make up a larger proportion of the urinary excretion products. In addition, methylbenzaldehyde (the product of the action of alcohol dehydrogenase on methylbenzyl alcohol) has been detected in animals, where it may exert toxic effects, but its presence has not been confirmed in humans. The biotransformation of Xylene (FIRIN TİNER, Ksilen) in humans proceeds primarily by the oxidation of a side-chain methyl group by microsomal enzymes (mixed function oxidases) in the liver to yield toluic acids (methylbenzoic acids). These toluic acids conjugate with glycine to form toluric acids (methylhippuric acids) that are excreted into the urine ... . This metabolic pathway accounts for almost all of the absorbed dose of Xylene (FIRIN TİNER, Ksilen), regardless of the isomer, route of administration, administered dose, or duration of exposure. Minor metabolic pathways that account for <10% of the absorbed dose include the elimination of unchanged compound in the exhaled breath and in the urine, and the urinary elimination of methylbenzyl alcohols, o-toluylglucuronides (o-toluic acid glucuronide), Xylene (FIRIN TİNER, Ksilen) mercapturic acid ... , and xylenols (dimethylphenols). ... The metabolism of Xylene (FIRIN TİNER, Ksilen) in animals is qualitatively similar to that of humans, though quantitative differences do exist. ... The differences in Xylene (FIRIN TİNER, Ksilen) metabolism observed between humans and animals may, in part, be explained by differences in the size of the doses given to humans and animals in experimental studies. Metabolism of Xylene (FIRIN TİNER, Ksilen)s by humans consists primarily of side-chain oxidation to form methylbenzoic acid ... Methylbenzoic acid is conjugated principally with glycine and excreted in urine as methylhippuric acid. It has been estimated that glycine conjugation would be saturated in humans exposed to about 1174 mg/cu m (270 ppm) Xylene (FIRIN TİNER, Ksilen) while working and to about 3393 mg/cu m (780 ppm) while resting ... A small amount of the glucuronide ester of methylbenzoic acid and trace levels of methylbenzyl alcohol have been detected in human urine ... Hydroxylation of the aromatic ring with the formation of dimethylphenols seems to be a minor pathway in humans. The following dimethylphenol isomers have been identified in human urine: 2,3- and 3,4-dimethylphenol (with o-Xylene (FIRIN TİNER, Ksilen)), 2,4-dimethylphenol (with m-Xylene (FIRIN TİNER, Ksilen)) and 2,5-dimethylphenol (with p-Xylene (FIRIN TİNER, Ksilen)). Most studies on metabolism of Xylene (FIRIN TİNER, Ksilen)s have been performed on rat. The principal pathway involves side-chain oxidation to methylbenzoic acid via methylbenzyl alcohol and methylbenzyl aldehyde. Methylbenzoic acid is then conjugated with glycine or glucuronic acid ... Conjugation with glycine to form methylhippuric acid predominates for m- and p-Xylene (FIRIN TİNER, Ksilen) ... In the case of o-Xylene (FIRIN TİNER, Ksilen), glucuronide formation has been reported to predominate ... A separate minor pathway resulting in urinary excretion of thioethers has been studied ... This pathway appears to be more important for o-Xylene (FIRIN TİNER, Ksilen) than for the other isomers. Hydroxylation of the aromatic ring with the formation of dimethylphenols has been reported to be another minor metabolic pathway in rats. After an intraperitoneal injection of 87-348 mg/kg body weight m-Xylene (FIRIN TİNER, Ksilen) to rats, 53-75% of the dose was excreted as m-methyl-hippuric acid in urine during 24 hr. After an intraperitoneal dose of 319 mg/kg body weight the proportion excreted as mercapturic acids was calculated to be 10% for o-Xylene (FIRIN TİNER, Ksilen) and 0.6-1.3% for m- and p-Xylene (FIRIN TİNER, Ksilen). When volunteers were exposed to about 195 mg/cu m (45 ppm) of o-, m- or p-Xylene (FIRIN TİNER, Ksilen) for 8 hr, about 95-99% of the dose was excreted as methylhippuric acid in urine. Dimethylphenol excretion was estimated to be 0.1 to 2% of the dose absorbed ... About 90% of the absorbed dose of m-Xylene (FIRIN TİNER, Ksilen) was excreted as methylhippuric acid after exposure to 435 mg/cu m (100 ppm) for 4 hr ... On the other hand, after exposure to 600 mg/cu m (138 ppm) of o-Xylene (FIRIN TİNER, Ksilen), only 46% was excreted in urine as methylhippuric acid and only trace amounts of the o-methylbenzoyl glucuronide were detected. The principal pathway in the rat for m- and p-Xylene (FIRIN TİNER, Ksilen) is the same as that in humans, sidechain oxidation and conjugation with glycine and glucuronic acid. For o-Xylene (FIRIN TİNER, Ksilen), the glucuronide formation predominates and a small amount of sulfate conjugate also is produced. Hydroxylation of the aromatic ring of Xylene (FIRIN TİNER, Ksilen)s is also a minor pathway in the rat. p-Xylene (FIRIN TİNER, Ksilen), also known as para-Xylene (FIRIN TİNER, Ksilen) or 4-Xylene (FIRIN TİNER, Ksilen), belongs to the class of organic compounds known as p-Xylene (FIRIN TİNER, Ksilen)s. These are aromatic compounds that contain a p-Xylene (FIRIN TİNER, Ksilen) moiety, which is a monocyclic benzene carrying exactly two methyl groups at the 1- and 4-positions. p-Xylene (FIRIN TİNER, Ksilen) exists as a liquid and is considered to be practically insoluble (in water) and relatively neutral. p-Xylene (FIRIN TİNER, Ksilen) can be converted into 2, 5-dimethyl-p-phenylenediamine. IDENTIFICATION: 4-Xylene (FIRIN TİNER, Ksilen) is a colorless liquid. It is also a colorless plate or prism at low temperatures. It has a sweet aromatic odor. 4-Xylene (FIRIN TİNER, Ksilen) is slightly soluble in water. It occurs naturally in petroleum and coal tar. 4-Xylene (FIRIN TİNER, Ksilen) is formed during forest fires and is naturally given off from corn, alfalfa and cereal silage. USE: 4-Xylene (FIRIN TİNER, Ksilen) is an important commercial chemical that is used to make other chemicals, polyester resins and fibers, in the manufacture of vitamins and insecticides and in paint and paint products. It is typically found in a mixture with other Xylene (FIRIN TİNER, Ksilen)s (2- and 3-Xylene (FIRIN TİNER, Ksilen)). EXPOSURE: Workers that use 4-Xylene (FIRIN TİNER, Ksilen) may breathe in mists or have direct skin contact. The general population may be exposed by breathing air, eating food and drinking water, smoking cigarettes and contact with consumer products containing Xylene (FIRIN TİNER, Ksilen)s (gasoline, paints, varnishes, paint thinner, etc.). If 4-Xylene (FIRIN TİNER, Ksilen) is released to the environment, it will be broken down in air. It is not expected to be broken down by sunlight. It will move into air from moist soil and water surfaces. It is expected to move moderately through soil. It will be broken down by microorganisms, and is not expected to build up in fish. RISK: Risks discussed below are for Xylene (FIRIN TİNER, Ksilen) mixtures in general, as 4-Xylene (FIRIN TİNER, Ksilen) is most often found in a mixture with 2- and 3-Xylene (FIRIN TİNER, Ksilen). Studies indicate that risk of toxicity is the same for 2-, 3-, and 4-Xylene (FIRIN TİNER, Ksilen), or a mixture of the three chemicals. Xylene (FIRIN TİNER, Ksilen)s are skin, eye, nose, and throat irritants. Nervous system effects (headache, dizziness, confusion, incoordination, impaired balance, forgetfulness, etc.) are the primary effects observed in humans that breathe high levels of Xylene (FIRIN TİNER, Ksilen)s. Difficulty breathing, nausea, and damage to the lungs, liver, and kidneys have also been observed following exposure to high vapor levels. Unconsciousness and even death may occur at very high levels. Similar effects were noted in laboratory animals exposed to moderate-to-high levels of Xylene (FIRIN TİNER, Ksilen)s. Studies on the potential for Xylene (FIRIN TİNER, Ksilen)s to cause infertility, abortion, or birth defects in humans are considered inadequate to assess risk due to simultaneous exposure to other solvents (e.g. benzene). Abortion and delayed growth and development of offspring were observed in laboratory animals following exposure to Xylene (FIRIN TİNER, Ksilen) during pregnancy, but only at doses that were toxic to the mothers. Infertility and major birth defects were not observed in laboratory animals following exposure before and/or during pregnancy. No specific forms of cancer have been specifically associated with Xylene (FIRIN TİNER, Ksilen) exposure in workers exposed to solvent mixtures (including Xylene (FIRIN TİNER, Ksilen)s). No evidence of cancer was observed in laboratory animals following lifetime oral exposure to Xylene (FIRIN TİNER, Ksilen)s. The U.S. EPA IRIS program determined that data are inadequate for an assessment of the human carcinogenic potential of Xylene (FIRIN TİNER, Ksilen)s. The International Agency for Research on Cancer has determined that Xylene (FIRIN TİNER, Ksilen)s are not classifiable as to their carcinogenicity to humans based on lack of adequate human data and inconclusive animal data. The potential for Xylene (FIRIN TİNER, Ksilen) to cause cancer in humans has not been assessed by the U.S. National Toxicology Program 13th Report on Carcinogens. (SRC) Low temperature fractional crystallization was the first and for many years the only commercial technique for separating PX /4-Xylene (FIRIN TİNER, Ksilen)/ from mixed Xylene (FIRIN TİNER, Ksilen)s. ... PX has a much higher freezing point than the other Xylene (FIRIN TİNER, Ksilen) isomers. Thus, upon cooling, a pure solid phase of PX crystallizes first. Eventually, upon further cooling, a temperature is reached where solid crystals of another isomer also form. This is called the eutectic point. PX crystals usually form at about -4 °C and the PX-MX /4-Xylene (FIRIN TİNER, Ksilen)-3-Xylene (FIRIN TİNER, Ksilen)/ eutectic is reached at about -68 °C. In commercial practice, PX crystallization is carried out at a temperature just above the eutectic point. At all temperatures above the eutectic point, PX is still soluble in the remaining C8 aromatics liquid solution, called mother liquor. This limits the efficiency of crystallization processes to a per pass PX recovery of about 60-65%. The solid PX crystals are typically separated from the mother liquor by filtration or centrifugation. Xylene (FIRIN TİNER, Ksilen) is produced primarily by the catalytic reforming of naphtha streams, which are rich in alicyclic hydrocarbons. The aromatic reformate fractions consist mainly of benzene, toluene and mixed Xylene (FIRIN TİNER, Ksilen)s, Xylene (FIRIN TİNER, Ksilen)s representing the largest fraction. The Xylene (FIRIN TİNER, Ksilen) isomers are separated from the reformate by extraction and distillation on the basis of differences in boiling point ... 4-Xylene (FIRIN TİNER, Ksilen) is separated by continuous crystallization or adsorption from the mixed Xylene (FIRIN TİNER, Ksilen)s or isomerized from the 3-Xylene (FIRIN TİNER, Ksilen)/4-Xylene (FIRIN TİNER, Ksilen) distillate; 3-Xylene (FIRIN TİNER, Ksilen) is obtained by selective crystallization or solvent extraction of meta-para mixtures. The commercial product "mixed Xylene (FIRIN TİNER, Ksilen)s" is a technical product generally containing approximately 40% m-Xylene (FIRIN TİNER, Ksilen) and 20% each of o-Xylene (FIRIN TİNER, Ksilen), p-Xylene (FIRIN TİNER, Ksilen), and ethylbenzene, as well as small quantities of toluene. The aim of this study was to develop an analytical method to monitor the saliva matrix for ototoxic solvents absorption: the method is based on headspace gas chromatography/mass spectrometry and represents an alternative biological monitoring for investigating low exposure to hazardous ototoxic solvents. Simultaneous determination of toluene, ethylbenzene, Xylene (FIRIN TİNER, Ksilen)s and styrene has been carried out and the method has been optimized for both instrumental parameters and samples treatment. Chromatographic conditions have been set in order to obtain a good separation of Xylene (FIRIN TİNER, Ksilen) isomers due to the interest in p-Xylene (FIRIN TİNER, Ksilen) as ototoxic one. Method validation has been performed on standards spiked in blank saliva by using two internal standards (2-fluorotoluene and deuterated styrene-d(8)). This method showed the possibility to detect the target compounds with a linear dynamic range of at least a 2 orders of magnitude characterized by a linear determination coefficient (r(2)) greater than 0.999. The limit of detection (LOD) ranged between 0.19 ng/mL (styrene) and 0.54 ng/mL (m-Xylene (FIRIN TİNER, Ksilen)) and the lower limit of quantification (LLOQ) ranged between 0.64 ng/mL (styrene) and 1.8 ng/mL (m-Xylene (FIRIN TİNER, Ksilen)). The method achieved good accuracy (from 99 to 105%) and precision for both intra- and inter-assay (relative standard deviation ranging from 1.7 to 13.8%) for all six compounds concerned. The repeatability was improved by adding sodium sulphate to the matrix. Saliva samples resulted stable for at least 7 days after collection, if stored in headspace vials, at the temperature of 4 degrees C. An evaluation of the main sources of uncertainty of the method is also included: expanded uncertainties ranges between 10 and 16% for all of the target compounds. In summary, the headspace gas chromatography/mass spectrometry method is a highly sensitive, versatile and flexible technique for the biological monitoring of exposure to ototoxic solvents by saliva analysis. Commercial or mixed Xylene (FIRIN TİNER, Ksilen) usually contains about 40-65% m-Xylene (FIRIN TİNER, Ksilen) and up to 20% each of o-Xylene (FIRIN TİNER, Ksilen) and p-Xylene (FIRIN TİNER, Ksilen) and ethylbenzene. Xylene (FIRIN TİNER, Ksilen)s are released into the atmosphere as fugitive emissions from industrial sources, from auto exhaust, and through volatilization from their use as solvents. Acute (short- term) inhalation exposure to mixed Xylene (FIRIN TİNER, Ksilen)s in humans results in irritation of the eyes, nose, and throat, gastrointestinal effects, eye irritation, and neurological effects. Chronic (long-term) inhalation exposure of humans to mixed Xylene (FIRIN TİNER, Ksilen)s results primarily in central nervous system (CNS) effects, such as headache, dizziness, fatigue, tremors, and incoordination; respiratory, cardiovascular, and kidney effects have also been reported. EPA has classified mixed Xylene (FIRIN TİNER, Ksilen)s as a Group D, not classifiable as to human carcinogenicity. The major hazards encountered in the use and handling of 4-Xylene (FIRIN TİNER, Ksilen) stem from its toxicologic properties and flammability. Exposure to this colorless sweet-smelling liquid (solid, below 13 °C) may occur from its use as a solvent, as a component of gasoline, and as a chemical intermediate. Toxic by all routes of exposure (ie, dermal, ingestion, and inhalation), 4-Xylene (FIRIN TİNER, Ksilen) can cause effects including headache, dizziness, skin and eye irritation, kidney and liver damage, pulmonary edema, coma, and death. The ACGIH recommends a workplace exposure limit (TLV) of 100 ppm an 8-hr time-weighted average (TWA); however, to assure protection, wear an approved canister or air-supplied mask, face shield, plastic gloves, and boots. In emergency situations, a self-contained breathing apparatus and full protective clothing are recommended. If contact does occur, immediately flush exposed eyes with running water, wash exposed skin with soap and water, and remove contaminated clothing. Individuals with diseases of the central nervous system, liver, kidneys, and blood should be protected from exposure. 4-Xylene (FIRIN TİNER, Ksilen) is easily ignitable by heat, sparks, or flame (flash point: 25 °C, closed cup), and may do so explosively in an enclosed area. Also, vapor may travel a considerable distance to a source of ignition and flash back. The heat of a fire may cause containers to explode and/or cause thermal degradation of 4-Xylene (FIRIN TİNER, Ksilen), producing irritating and poisonous gases. Fires involving 4-Xylene (FIRIN TİNER, Ksilen) may be extinguished with dry chemical, CO2, water spray, fog, or foam. For massive fires in enclosed areas, use unmanned hose holders or monitor nozzles. If a 4-Xylene (FIRIN TİNER, Ksilen) tank car or truck is involved in a fire, isolate 1/2 mile in all directions. Runoff from fire control water may cause pollution and, upon entering a sewer, may create an explosion hazard. 4-Xylene (FIRIN TİNER, Ksilen) should be stored in closed containers, in cool, well ventilated areas (outdoor or detached areas are preferable), away from sources of ignition, oxidizing agents, and any activity that could cause physical damage to containers. For small spills of 4-Xylene (FIRIN TİNER, Ksilen), take up with sand or other non-combustible absorbent and place in containers for later disposal, or absorb on paper and evaporate in an appropriate exhaust hood. For large spills, isolate the area, dike far ahead of the spill, and collect the material for disposal. 4-Xylene (FIRIN TİNER, Ksilen) is a good candidate for the Belliot process of oxidative destruction, as well as liquid injection, rotary kiln, and fluidized bed incineration. 4-Xylene (FIRIN TİNER, Ksilen) may be sent to a solvent disposal company, but prior to implementing any land disposal of waste residue (including waste sludge), consult regulatory agencies for guidance. The rate constant for the vapor-phase reaction of 4-Xylene (FIRIN TİNER, Ksilen) with photochemically-produced hydroxyl radicals has been estimated as 1.43X10-11 cu cm/molecule-sec at 25 °C(1). This corresponds to an atmospheric half-life of about 26 hours at an atmospheric concentration of 5X10+5 hydroxyl radicals per cu cm(2). The rate constant for the vapor-phase reaction of 4-Xylene (FIRIN TİNER, Ksilen) with night-time nitrate radicals is 4.53X10-16 cu cm/molecule-sec at 25 °C(3). This corresponds to an atmospheric half-life of about 65 days at an atmospheric concentration of 2.5X10+8 nitrate radicals per cu cm(4). The rate constant for the vapor-phase reaction of 4-Xylene (FIRIN TİNER, Ksilen) with ozone is 1.36X1-21 cu cm/molecule-sec at 25 °C(3). This corresponds to an atmospheric half-life of about 23 years at an atmospheric concentration of 7X10+11 ozone molecules per cu cm(2). Products from the gas-phase reaction of nitrate with 4-Xylene (FIRIN TİNER, Ksilen) were 4-methylbenzaldehyde and 4-methylbenzy
XYLITOL
Xylitol is a chemical compound with the formula C5H12O5, or HO(CH2)(CHOH)3(CH2)OH; specifically, one particular stereoisomer with that structural formula.
Xylitol is a colorless or white crystalline solid that is freely soluble in water.


CAS Number: 87-99-0
E number: E967 (glazing agents, ...)
Chemical formula: C5H12O5



SYNONYMS:
meso-Xylitol, (2R,3R,4S)-Pentane-1,2,3,4,5-pentol, (2R,3R,4S)-Pentane-1,2,3,4,5-pentaol, (2R,3R,4S)-1,2,3,4,5-Pentahydroxypentane, Xylite,



Xylitol occurs naturally in small amounts in plums, strawberries, cauliflower, and pumpkin; humans and many other animals make trace amounts during metabolism of carbohydrates.
Unlike most sugar alcohols, xylitol is achiral.


Most other isomers of pentane-1,2,3,4,5-pentol are chiral, but xylitol has a plane of symmetry.
Industrial production starts with lignocellulosic biomass from which xylan is extracted; raw biomass materials include hardwoods, softwoods, and agricultural waste from processing maize, wheat, or rice.


The mixture is hydrolyzed with acid to give xylose.
The xylose is purified by chromatography.
Purified xylose is catalytically hydrogenated into xylitol using a Raney nickel catalyst.


The conversion changes the sugar (xylose, an aldehyde) into the primary alcohol, xylitol.
Xylitol can also be obtained by industrial fermentation, but this methodology are not as economical as the acid hydrolysis/chromatography route described above.


Fermentation is effected by bacteria, fungi, or yeast, especially Candida tropicalis.
According to the US Department of Energy, xylitol production by fermentation from discarded biomass is one of the most valuable renewable chemicals for commerce, forecast to be a US $1.4 billion industry by 2025.


Xylitol is a chemical compound with the formula C
5H12O5, or HO(CH2)(CHOH)3(CH2)OH; specifically, one particular stereoisomer with that structural formula.
Xylitol is a colorless or white crystalline solid that is freely soluble in water.


Xylitol can be classified as a polyalcohol and a sugar alcohol, specifically an alditol.
The name of Xylitol derives from Ancient Greek: ξύλον, xyl[on] 'wood', with the suffix -itol used to denote sugar alcohols.
Xylitol is a sugar alcohol that looks and tastes like sugar but has fewer calories and doesn’t raise blood sugar levels.


Xylitol may have health benefits but could cause digestive issues and other side effects.
Added sugar may be the singlemost unhealthy ingredient in the modern diet.
For this reason, sugar-free sweeteners like xylitol are becoming popular.


Several studies suggest that Xylitol has various important benefits, including improved dental health.
Xylitol is categorized as a sugar alcohol.
Chemically, sugar alcohols combine traits of sugar molecules and alcohol molecules.


Their structure allows them to stimulate the taste receptors for sweetness on your tongue.
Xylitol is found in small amounts in many fruits and vegetables and is therefore considered natural.
Humans even produce small quantities of Xylitol via normal metabolism.


Xylitol is a common ingredient in sugar-free chewing gums, candies, mints, diabetes-friendly foods and oral-care products.
Xylitol has a similar sweetness as regular sugar but contains 40% fewer calories:
Table sugar: 4 calories per gram


Xylitol: 2.4 calories per gram
Store-bought xylitol appears as a white, crystalline powder.
Since xylitol is a refined sweetener, it doesn’t contain any vitamins, minerals or protein.


In that sense, Xylitol provides only empty calories.
Xylitol can be processed from trees like birch or from a plant fiber called xylan.
Xylitol is an all-natural alternative to sugar.


Xylitol derives from the fibres of plants and can be extracted from a variety of vegetation including berries, mushrooms, birch bark and corn husks.
Xylitol's also produced in our body naturally.
Its flavour is as sweet as conventional sucrose sugar, but Xylitol has only two thirds the calorie count.


Pure xylitol comes in white crystals and looks and tastes like ordinary granulated sugar.
Xylitol has been traditionally used in chewing gums, toothpastes and mouthwash as it has a strong sweetening effect but no aftertaste.
From the late 2000s there has been a push to consume it instead of sugar, and its white granular form means Xylitol can be used sprinkled or in place of traditional sugar in cooking and baking in the exact same quantity.


Even though sugar alcohols are technically carbohydrates, most of them do not raise blood sugar levels and thereby don’t count as net carbs, making them popular sweeteners in low-carb products.
Though the word “alcohol” is part of its name, it’s not the same alcohol that makes you drunk.


Sugar alcohols are safe for people with alcohol addictions.
Xylitol Has a Very Low Glycemic Index and Doesn’t Spike Blood Sugar or Insulin.
One of the negative effects of added sugar — and high-fructose corn syrup — is that it can spike blood sugar and insulin levels.


Due to its high levels of fructose, it can also lead to insulin resistance and multiple metabolic problems when consumed in excess.
However, xylitol contains zero fructose and has negligible effects on blood sugar and insulin.
Therefore, none of the harmful effects of sugar apply to xylitol.


Xylitol’s glycemic index (GI) — a measure of how quickly a food raises blood sugar — is only 7, whereas regular sugar’s is 60–70 (6).
Xylitol can also be considered a weight-loss-friendly sweetener since it contains 40% fewer calories than sugar.
For people with diabetes, prediabetes, obesity or other metabolic problems, xylitol is an excellent alternative to sugar.


Xylitol is a natural sugar alcohol with a crystal structure.
Xylitol appears as a white powder.
Xylitol is soluble in water and water-based solvents.


Xylitol is a carbohydrate found in the birch tree and several kinds of fruit.
Xylitol has a chemical structure that looks like a cross between a sugar and an alcohol, but it is neither.
Xylitol is a natural sugar alcohol found in plants, including many fruits and vegetables.


Xylitol has a sweet taste and is often used as a sugar substitute.
In the US, products that contain xylitol are allowed to state that they reduce the risk for cavities.
People also use xylitol to prevent tooth plaque, ear infection, dry mouth, and many other conditions, but there is no good scientific evidence to support most of these uses.


Xylitol is a naturally occurring five-carbon sugar alcohol found in most plant material, including many fruits and vegetables.
Xylitol-rich plant materials include birch and beechwood.
Xylitol is widely used as a sugar substitute and in "sugar-free" food products.


Xylitol is a sugar alcohol in many fruits and vegetables.
Xylitol has a sharp, very sweet taste that is different from other types of sugar.
Manufacturers process xylitol to turn it into a sweetener for products such as: gums, candies, chocolates, cookies, sugar-free cake mixes, ice cream, and nut butters.


Xylitol is considered a “sugar alcohol” because it has a chemical structure that’s similar to both sugars and alcohol, but it’s technically neither of these in the way we usually think of them.
Xylitol’s in fact a type of low-digestible carbohydrate that includes fiber.


Xylitol is categorized as a sugar alcohol (also called polyol) because it has a molecular structure that is comparable to both sugar and alcohol despite being neither.
Xylitol is a type of fiber-containing, low-digestible carbohydrate.


Xylitol is produced in your body through the metabolism of a sugar xylose, a sugar that your digestive microbes cannot break down.
Xylitol can also be synthesized in a laboratory from xylose. Xylose occurs naturally in the bark of birch trees, corn cobs, various fruits (plums, strawberries), and vegetables (cauliflower and pumpkin).


Xylitol, a naturally occurring sugar alcohol used worldwide as a low-calorie sweetener, is clinically proven to reduce cavities and help prevent tooth decay and gum disease.
Xylitol is found in fibrous vegetables and fruits, corn cobs and hardwood trees (like birch).


Our bodies make up to 15 grams (four teaspoons) of xylitol daily.
Xylitol looks, feels and tastes like ordinary sugar (sucrose), but has 40 percent fewer calories and 75 percent fewer carbohydrates than sugar.
Additionally, xylitol is not easily converted to fat and has almost no effect on insulin levels, making it a great alternative for diabetics, bodybuilders and dieters.


Xylitol also is considered safe for pregnant and nursing women, babies and children.
Xylitol can replace sugar in cooking, baking (except when sugar is needed for yeast to rise) or in beverages as a sweetener.
Xylitol also is included as an ingredient in chewing gums, mints, candies, toothpastes, mouth rinses and nasal sprays.


Xylitol is the incredible pure sweetener that more and more people are turning to as an ideal substitute for sugar.
Unlike sugars such as sucrose and fructose, Xylitol alcohol won’t promote tooth decay, has a low glycemic impact and has around one-third less calories than other sugars, making it a low-calorie, diabetic-friendly and keto diet-friendly sweetener that’s hard to beat.


Xylitol is a 100% natural sweetener derived from vegetable sources.
Twenty years of research shows xylitol efficacy treating dry mouth and reducing tooth decay.
Its many benefits make Xylitol an adapted response to some public health problems related to the general over-consumption of sugar.


German chemists discovered the naturally occurring sugar in the late 19th century in birch tree bark, and since then, Xylitol’s also been naturally found in fruits and vegetables.
X-PUR nad Xylimelts' xylitol is made of corn.


Marketing myths abound that the plant source of xylitol impacts the end product (i.e., corn vs. birch), but science shows there is no molecular difference in the harvested end product with regards to its source.
X-PUR and XyliMelts' xylitol comes from some remarkable family corn farmers and offers the purest medicinal grade xylitol possible; non-GMO, renewable corn crops.


Xylitol is a natural sweetener extracted from green oak, taste is like sugar cane but low calorie.
Xylitol is proved that it helps to prevent the cavity by the dental association in many countries.
Xylitol is a sugar alcohol that may be plant-derived or synthetic (Paula’s Choice uses the former).


In the plant world, xylitol naturally occurs in many fruits and vegetables, including mushrooms, lettuce, oats strawberries, bananas, and yellow plums.
Xylitol can also be derived from wood or upcylced paper.
Research has shown that, like the skin-replenishing ingredient glycerin and similar sugar-derived ingredient sorbitol, xylitol hydrates due to its humectant (moisture-binding) properties.


Xylitol also has an influential role in normalizing skin and the natural process keratinocytes (skin cells) go through as they work their way from the lower to the upper layers to the surface.
Part of this is due to Xylitol's ability to squelch damaging factors in skin that would otherwise throw skin’s natural processes off track.


Xylitol is considered a nutritive sweetener and when added to foods or foods that naturally contain xylitol are eaten, research has shown it has prebiotic action that positively influences the gut microbiome.
Xylitol is a source of galactooligosaccharides, which are primary responsible for its prebiotic ability


When combined with other oligosaccharides such as those derived from fructose, xylitol helps keep the population of good and bad bacteria on skin’s surface balanced.
Xylitol, a naturally occurring sugar alcohol used worldwide as a low-calorie sweetener, is clinically proven to reduce cavities and help prevent tooth decay and gum disease.


Xylitol is a natural sugar alcohol.
Xylitol's an ingredient found in many oral care products, such as toothpaste, mouthwash, and chewing gum.
Xylitol's used to prevent cavities by stopping the growth of bad bacteria in your mouth.


Xylitol also works to treat dry mouth by helping you produce more saliva.
The amount of xylitol found in dental products isn't know to cause noticeable side effects.
Xylitol-containing dental products are typically available over the counter without a prescription.



USES and APPLICATIONS of XYLITOL:
Xylitol is considered safe as used in cosmetics.
In the United States, Xylitol is freely permitted as a food additive and is often used as a sugar (sucrose) substitute since it digests slower, thus doesn’t raise blood sugar quickly.


Usage levels typically go up to 10%, with much lower amounts used when Xylitol is combined with other humectants and prebiotics.
Xylitol is used as a sugar substitute in such manufactured products as drugs, dietary supplements, confections, toothpaste, and chewing gum, but is not a common household sweetener.


Xylitol has negligible effects on blood sugar because its assimilation and metabolism are independent of insulin.
Xylitol is approved as a food additive in the United States and elsewhere.
Xylitol is often marketed as "birch sugar".


Xylitol is also found as an additive to saline solution for nasal irrigation and has been reported to be effective in improving symptoms of chronic sinusitis.
Xylitol can also be incorporated into fabrics to produce a cooling fabric.


When moisture, such as sweat, comes into contact with the xylitol embedded in the fabric, it produces a cooling sensation.
Xylitol is used as a food additive and sugar substitute.
Xylitol's European Union code number is E967.


Applications of Xylitol: Confectionery, Chewing-gum, Chewy sweet & marshmallow, and Filling & coating.
Xylitol is used as a sugar substitute, either complimenting your diet or completely replacing other sugars.
Replacing sugar with xylitol in food products may promote better dental health, but evidence is lacking on whether xylitol itself prevents dental cavities.


Skin and hair care uses of Xylitol: Xylitol is used in skin care products because it has anti-aging benefits and can help improve moisture retention.
Chewing gum and candy uses of Xylitol: Because of its pleasant cooling effect, xylitol is extensively utilized as a sugar alternative in chewing gum.
Pharmaceuticals uses of Xylitol: Xylitol is sometimes added to medications to sweeten the flavor without sugar.


When used as a moisturizer, Xylitol helps to increase the moisture level of the skin and keep it soft and moist.
Xylitol also has the potential to protect the skin barrier, which protects the skin against environmental factors.
Xylitol is used as a sweetener in oral care products and supports oral health by reducing tooth decay.


The usage rate varies between 0.1% and 10% depending on the effect of Xylitol and its interaction with other substances.
Xylitol is a type of natural sweetener that is extracted from foods like plums, strawberries and pumpkin.
Because it inhibits the bacteria that cause cavities, Xylitol is often used to sweeten chewing gum, mouth wash, syrups and dental creams.


Xylitol is also low in calories and has a low glycemic index, making it a great natural option to help manage glucose levels and promote weight loss.
Xylitol can be found in granulated form at pharmacies, natural health stores and grocery stores.
Xylitol can tolerate high temperatures and has a mild, sweet taste similar to sugar, and can therefore be used to sweeten juice, tea, coffee, cakes and pies.


Xylitol is naturally sweet and has fewer calories than cane sugar, which is why it is often used as a non-sugar sweetener.
Xylitol is commonly used sweetener in gum, it is naturally- occurring in human metabolism.
With its low calories (40 % less than sugar), low Glycemic index and low insulin usage to metabolize, Xylitol is often considered a healthier alternative to sugar.


Xylitol also promotes beneficial properties to oral health.
Xylitol tastes sweet but, unlike sugar, it doesn't cause tooth decay.
Xylitol reduces levels of decay-causing bacteria in saliva and also acts against some bacteria that cause ear infections.


Xylitol's widely used in "sugar-free" chewing gums, mints, and other candies.
The effects of xylitol on dental caries have been widely studied, and xylitol is added to some chewing gums and other oral care products to prevent tooth decay and dry mouth.


Xylitol is a non-fermentable sugar alcohol by most plaque bacteria, indicating that it cannot be fermented into cariogenic acid end-products.
Xylitol works by inhibiting the growth of the microorganisms present in plaque and saliva after it accummulates intracellularly into the microorganism.
The recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events
Xylitol is also an ingredient in some oral care products, such as toothpastes and mouthwashes, both as a flavor enhancer and a cavity-fighting agent.


-Sugar replacement uses of Xylitol:
Sucrose has about 4 calories per gram, but xylitol has just 2.4 calories per gram.
Despite being lower in calories, xylitol has the same sweetness as sugar.
Because most sugar alcohols are not as sweet as sugar, xylitol is mostly preferred as a sugar substitute.


-Sauces and condiments uses of Xylitol:
Sauces and condiments tend to be fairly high in sugar; for example, a tablespoon of ketchup can have 4.1 grams of sugar.
Xylitol is a sugar-free substitute that can be used to sweeten such products instead.


-Baking uses of Xylitol:
Although it does not brown like conventional sugar, xylitol can be used cup for cup as a sugar substitute in baking because it retains its sweetness after being exposed to high temperatures.


-Dental care uses of Xylitol:
Xylitol is found in dental care products, such as mouthwashes and toothpaste.
Xylitol supports oral health by limiting the buildup of bacteria and reducing the risk of dental cavities.


-Xylitol has a similar level of sweetness to sugar but with a fraction of the calories.
Xylitolis a popular ingredient in a variety of products, including sugar-free gum and toothpaste.
Manufacturers add xylitol to a range of foods, including:
s*ugar-free candies, such as gum, mints, and gummies
*jams and jellies
*honey
*nut butters, including peanut butter
*yogurt


-Xylitol is also an ingredient in some dental care products, including:
*toothpaste
*mouthwash
*other fluoride products



PROPER USE OF XYLITOL:
To help prevent cavities, you need approximately six to eight grams of xylitol taken (chewed or ingested) throughout the day.
To help prevent ear, nose and throat problems such as sinus conditions and middle ear infections, approximately 10 grams of Xylitol daily is recommended.

If used only occasionally or just once a day, xylitol may not be effective, regardless of the amount.
Use xylitol at least three times each day – five times is preferable – for at least five minutes right after meals and snacks.
Between meals, opt for xylitol-sweetened products that encourage chewing/sucking to keep the xylitol in contact with your teeth.
The xylitol effect is long lasting and possibly permanent.



WHERE IS XYLITOL FOUND?
Xylitol is manufactured into a white powder that looks and tastes similar to sugar.
In many countries Xylitol has been approved for use in oral care products, pharmaceuticals, and as a food additive.
Over recent years, the number and types of products that contain xylitol has greatly increased.

Example products include sugar-free gum, candies, breath mints, baked goods, peanut butter, pudding snacks, cough syrup, chewable or gummy vitamins, and supplements or over the counter medications, mouthwash, and toothpaste.

Xylitol is also showing up in over-the-counter nasal sprays, skin care products, laxatives, digestive aids, allergy medicines, dry mouth lozenges, sleep supplements, as well as prescription human medications, especially those formulated as quick dissolve tablets or liquids.



WHY IS XYLITOL INCREASING IN POPULARITY AND USE?
Xylitol has the same sweetness as sucrose but contains only about two-thirds the calories.
As a sugar substitute, Xylitol is lower on the glycemic index, a scale that ranks carbohydrate-rich foods by how much they raise blood sugar levels, compared to glucose.

Being lower on the glycemic index makes xylitol useful for diabetics or people on low carbohydrate diets.
With respect to oral health, research has shown that xylitol helps reduce the formation of plaque, inhibits dental cavities, and stimulates the production of saliva.



XYLITOL AT A GLANCE:
*A sugar that may be plant-derived or lab-made
*Has prebiotic ability that helps skin stay healthy
*Attracts and binds moisture without a greasy feel
*Approved for use in foods and is safe for skin



POTENTIAL BENEFITS OF XYLITOL:
Xylitol has several potential health benefits, including:

*Low glycemic index
Xylitol has a low glycemic index (GI).
This means that consuming it does not cause spikes in blood glucose or insulin levels in the body.

For this reason, xylitol is a good sugar substitute for people with diabetes.
Due to its low GI, xylitol is also a weight loss-friendly sugar substitute.
Also, a 2015 study revealed that xylitol had significant blood glucose-lowering effects in rats that ate high-fat diets.


*Dental health
Xylitol is an ingredient in many dental hygiene products, including toothpaste and mouthwash.
This is due to the fact that xylitol is non-fermentable, which means that the bacteria in the mouth cannot convert it into the harmful acid that causes tooth decay.

The oral bacterium Streptococcus mutans is largely responsible for plaque, which is the sticky, white substance that can accumulate on the outside of a person’s teeth.
Plaque binds lactic acid against the surface of the tooth.

This acid breaks down the enamel and leads to tooth decay.
While it is normal for people to have some plaque on their teeth, excess amounts can lead to tooth decay, cavities, and gum disease.
A 2017 systematic review suggests that xylitol reduces the amount of S. mutans bacteria in the mouth, which reduces the amount of plaque and may help prevent tooth decay.



CAN YOU GET XYLITOL FROM FOODS?
Xylitol is extracted from plant material.
The amount naturally found in foods is very small.
However, Xylitol is increasingly found as an ingredient (additive) in more and more foods and health products.
In addition to gum, xylitol can be found in some hard candies, chocolate, table syrup, jams, jellies, baked goods, cough syrup, vitamins, some nut butters, over-the-counter medications and many others.



7 HEALTH BENEFITS OF XYLITOL:
1. Reduces oral bacteria
Xylitol has been shown to have promising results in preventing dental cavities, and both the American Dental Association and the FDA have recognized xylitol to be helpful for oral health.

Unlike sugar, xylitol is not metabolized in the mouth to acids that cause tooth decay.
Instead, Xylitol reduces plaque formation and the risk of tooth enamel erosion.
Xylitol can also reduce gingivitis (inflammation of gums) by lowering inflammation and inhibiting oral bacteria (Streptococcus mutans).

Xylitol is generally considered safe during pregnancy.
In fact, chewing xylitol gum lowers the oral bacterial load and reduces the transfer of mutant streptococci to babies throughout pregnancy and after delivery.


2. Good for people with diabetes
Xylitol is structurally different from sucrose.
Unlike sugar, xylitol is absorbed slowly and incompletely in the small intestine.

This makes Xylitol and other sugar alcohols beneficial for people with diabetes.
The absorbed xylitol is readily utilized for energy production and has a low glycemic index level, which means it does not spike blood sugar levels.
This reduces the need for insulin.


3. Helps with weight loss
Xylitol is often used in place of sugar because it contains 40% fewer calories.
A teaspoon of sugar contains 16 calories, while a teaspoon of xylitol contains only 9.6 calories.
Due to the lower calorie content, xylitol can be helpful if you are trying to lose weight.


4. Prevents ear infections
Xylitol in chewing gum may prevent middle ear infections (otitis media) in children.
Otitis medium is a common bacterial infection.

The two most common bacteria that cause middle ear infections and sinusitis are Streptococcus pneumoniae and Haemophilus influenza.
Xylitol reduces the bacterial load of Streptococcus pneumoniae, which enhances the effect of antibiotics, such as amoxicillin, against the bacteria.


5. Boosts collagen
Xylitol stimulates collagen formation, which has been shown to improve skin elasticity and help prevent premature wrinkles.


6. Antioxidant properties
Xylitol is said to have antioxidant-inducing effects, which reduce inflammation in the body and help fight disease.


7. Prevents osteoporosis
Xylitol prevents osteoporosis because it aids calcium absorption, resulting in increased bone density and mineral content.



WHY DO PEOPLE TAKE XYLITOL?
Xylitol is a sugar-free sweetener added to some foods.
Xylitol's nearly as sweet as sugar (sucrose), but has fewer calories.
People with diabetes sometimes use xylitol as a sugar substitute.

Blood sugar levels stay at a more constant level with xylitol than with regular sugar.
This is because it is absorbed more slowly by the body.
Some types of gum or oral care products, such as toothpaste and mouthwash, also contain xylitol.
Mouth bacteria can't use xylitol as a source of energy, so it may help prevent tooth decay and the buildup of plaque.



BENEFITS OF XYLITOL:
A person might try xylitol because it may provide the following benefits:

*Preventing cavities
Most research into xylitol has focused on its potential to fight dental cavities.
Xylitol helps prevent the formation of plaque, and it may slow bacterial growth associated with cavities.
According to a 2020 review, xylitol may be especially effective against the bacterial strains Streptococcus mutans and Streptococcus sangui.

The researchers also found evidence that xylitol may help remineralize the teeth, supporting the reversal of damage from bacteria, and alleviate tooth sensitivity.
Xylitol may even help reduce the risk of future cavities.

*Treating mouth sores
Xylitol is an anti-inflammatory agent that may kill certain bacteria, including those that form plaque on the gums and teeth.
Angular chelitis is a painful inflammatory skin condition that affects the corners of the lips and mouth.



WHAT ARE THE HEALTH BENEFITS OF XYLITOL?
Some research suggests that xylitol may have health benefits, such as improving dental health, preventing ear infections, and possessing antioxidant properties.
Xylitol is a lower-calorie sugar substitute with a low glycemic index.

Xylitol is a sugar alcohol, which is a type of carbohydrate and does not actually contain alcohol.
Xylitol occurs naturally in small amounts in fibrous fruits and vegetables, trees, corncobs, and even the human body.
Manufacturers use xylitol as a sugar substitute because its sweetness is comparable with that of table sugar but with fewer calories.

Xylitol is a common ingredient in many products, from sugar-free chewing gum to toothpaste.
People also use xylitol as a table-top sweetener and in baking.



FOOD PROPERTIES OF XYLITOL:
*Nutrition, taste, and cooking
Humans absorb xylitol more slowly than sucrose, and xylitol supplies 40% fewer calories than an equal mass of sucrose.
Xylitol has about the same sweetness as sucrose, but is sweeter than similar compounds like sorbitol and mannitol.

Xylitol is stable enough to be used in baking, but because xylitol and other polyols are more heat-stable, they do not caramelise as sugars do.
When used in foods, they lower the freezing point of the mixture.


*Food risks
No serious health risk exists in most humans for normal levels of consumption.
The European Food Safety Authority has not set a limit on daily intake of xylitol.


*Metabolism
Xylitol has 2.4 kilocalories of food energy per gram of xylitol (10 kilojoules per gram) according to U.S. and E.U. food-labeling regulations.
The real value can vary, depending on metabolic factors.
Primarily, the liver metabolizes absorbed xylitol.

The main metabolic route in humans occurs in cytoplasm, via nonspecific NAD-dependent dehydrogenase (polyol dehydrogenase), which transforms xylitol to D-xylulose.
Specific xylulokinase phosphorylates it to D-xylulose-5-phosphate.
This then goes to pentose phosphate pathway for further processing.

About 50% of eaten xylitol is absorbed via the intestines.
Of the remaining 50% that is not absorbed by the intestines, in humans, 50–75% of the xylitol remaining in the gut is fermented by gut bacteria into short-chain organic acids and gases, which may produce flatulence.

The remnant unabsorbed xylitol that escapes fermentation is excreted unchanged, mostly in feces; less than 2 g of xylitol out of every 100 g ingested is excreted via urine.
Xylitol ingestion also increases motilin secretion, which may be related to xylitol's ability to cause diarrhea.
The less-digestible but fermentable nature of xylitol also contributes to constipation relieving effects.



PRODUCTS CONTAINING XYLITOL:
Products containing xylitol, which are more expensive than those containing sucrose and sorbitol (another popular sweetener alternative), can be found on the Internet and at health food stores.
Prices range from around $1.50 for xylitol-sweetened gums to more than $50 for xylitol sweetener.
For the amount of xylitol to be at decay-preventing levels, it must appear as the first ingredient.



FUNCTIONAL PROPERTIES OF XYLITOL:
*Make it indulgent
*Mouthfeel enhancer
*Sweetness
*Make it better and healthier
*Blood glucose management
*Sugar-free



OTHER PROPERTIES AND BENEFITS OF XYLITOL:
*Xylitol is odorless, white crystalline powder
*Xylitol is sweetening power equal to that of sugar
*Xylitol has very good solubility



XYLITOL’S FACT:
Xylitol itself is sugar-free but contains natural sweetener, therefore it doesn’t cause the tooth decay.
Besides xylitol can help to prevent the cavity.
Since Xylitol gum & tablet has been introduced in Finland, the number of people who have cavities dropped dramatically thank to the habit taking Xylitol gum & tablet after each meal.



HEALTH BENEFITS OF XYLITOL:
*A natural sweetener found in many fruits and vegetables
*Non-GMO
*The low glycemic index (GI) of 7 compared to regular sugar with a GI of 60-70
*40% fewer calories and 75% fewer carbs than refined white sugar
*An excellent alternative to sugar for people with diabetes, pre-diabetes, obesity or other metabolic problems
*Reduces plaque in teeth by blocking sugar metabolism in bacteria
*Reduces ear infections in children by fighting yeast Candida Albicans
*Increases the absorption of calcium in the digestive system, is good for teeth and may protect against osteoporosis
*Reduces cavities and tooth decay by up to 30-85%
*Has prebiotic effects, feeding friendly bacteria in the gut



HEALTH EFFECTS OF XYLITOL:
*Dental care
A 2015 Cochrane review of ten studies between 1991 and 2014 suggested a positive effect in reducing tooth decay of xylitol-containing fluoride toothpastes when compared to fluoride-only toothpaste, but there was insufficient evidence to determine whether other xylitol-containing products can prevent tooth decay in infants, children or adults.

Subsequent reviews support the belief that xylitol can suppress the growth of pathogenic Streptococcus in the mouth, thereby reducing dental caries and gingivitis, although there is concern that swallowed xylitol may cause intestinal dysbiosis.


*Earache
In 2011 EFSA "concluded that there was not enough evidence to support" the claim that xylitol-sweetened gum could prevent middle-ear infections, also known as acute otitis media (AOM).

A 2016 review indicated that xylitol in chewing gum or a syrup may have a moderate effect in preventing AOM in healthy children.
Xylitol may be an alternative to conventional therapies (such as antibiotics) to lower risk of earache in healthy children – reducing risk of occurrence by 25% – although there is no definitive proof that it could be used as a therapy for earache.


*Diabetes
In 2011, EFSA approved a marketing claim that foods or beverages containing xylitol or similar sugar replacers cause lower blood glucose and lower insulin responses compared to sugar-containing foods or drinks.

Xylitol products are used as sucrose substitutes for weight control, as xylitol has 40% fewer calories than sucrose (2.4 kcal/g compared to 4.0 kcal/g for sucrose).
The glycemic index (GI) of xylitol is only 7% of the GI for glucose.


*Ear infections
The bacteria that cause tooth plaque can also accumulate behind the eardrum and cause infections of the middle ear.
Doctors call these infections acute otitis media (AOM).

A 2016 systematic review found moderate-quality evidence that chewing gum, lozenges, or syrup containing xylitol can reduce the occurrence of AOM from 30 to 22 percent among healthy children.
However, a 2014 study found xylitol syrup to be ineffective in reducing AOM in children at high risk of the infection.
These conflicting results indicate the need for more research regarding the use of xylitol as a preventive treatment for ear infections in children.


*Antioxidant properties
According to the National Center for Complementary and Integrative Health, free radicals cause oxidative stress, which can lead to cell damage and may play a role in the development of several conditions, including diabetes, cardiovascular disease, and cancer.
Laboratory studies show that antioxidants neutralize free radicals and counteract oxidative stress.



WHY WE PREFER CORN-BASED XYLITOL:
Xylitol is proudly produced from non-GMO corn cobs which would otherwise go to waste.
We believe corn-sourced xylitol is more sustainable than other sources such as birch trees which involves stripping the bark and eventually killing the tree.



WHAT ARE THE BENEFITS AND USES OF XYLITOL?
Xylitol is a low-calorie sweetener.
Xylitol is a sugar substitute in some gums and candies, and some oral care products, such as toothpastes, dental flosses, and mouthwashes, also contain it.
Xylitol can help prevent dental cavities, making it a tooth-friendly alternative to traditional sweeteners.
Xylitol is also low in calories, so opting for foods that contain this sweetener rather than sugar may help a person reach or maintain a moderate weight.



AVAILABILITY OF XYLITOL:
Xylitol is produced all year round and is available in healthfood shops and most large supermarkets in or around the sugar section.



COOK XYLITOL:
Xylitol can be used in place of sugar in any recipe that doesn't require the sugar to break down into liquid form - it is impossible for xylitol to caramelise even at an extremely high temperature and cooked at length.
Xylitol is particularly good in cakes and bakes, sprinkled on cereal or used in tea or coffee.



BENEFITS OF OTHER FORMS OF XYLITOL:
Xylitol is an ingredient in many products other than gum.
A person can also buy it as sugar-like granules and in other forms.
Early research suggests that xylitol may have benefits beyond oral health.


*Preventing ear infections:
A 2016 meta-analysis of three clinical trialsTrusted Source suggests that xylitol may play a role in preventing ear infections in children.
The team found moderate-quality evidence that giving children xylitol in any form could reduce their risk of acute otitis media, the most common type of ear infection.
In this meta-analysis, xylitol reduced the risk from around 30% to around 22%, compared with a control group.


*Helping with weight management:
A 2020 review found that this low-calorie sugar can increase satiety, helping people feel fuller for longer after eating.
Opting for sweets that contain xylitol instead of sugar can also help a person avoid sugar’s empty calories.
As such, this switch may be a good option for people looking to manage their weight without making drastic changes to their diet.
However, no research demonstrates that switching to foods containing xylitol, not sugar, helps with weight loss more than traditional methods.


*As a sugar substitute for people with diabetes:
A small 2021 pilot study found that xylitol had only very small effects on blood glucose and insulin levels.
This suggests that it may be a safe sugar alternative for people with diabetes.


*Other health benefits:
Xylitol has antibacterial and anti-inflammatory properties that may provide additional health benefits
A 2020 review described evidence that xylitol may also help with:

*reducing constipation
*reducing obesity, especially as a sugar substitute
*supporting better blood glucose management in people with diabetes
*reducing the risk and severity of respiratory infections
And research from 2016 indicates that xylitol may help improve calcium absorption to prevent bone density loss and reduce the risk of osteoporosis.



IS XYLITOL TRULY "NATURAL"?
Xylose, not xylitol, is naturally obtained from bark of the birch tree and from certain fruits.
Yet, just because something is “natural” doesn’t mean that it is good for you.



XYLITOL BOOSTS DENTAL HEALTH:
Many dentists recommend using xylitol-sweetened chewing gum — and for good reason.
Studies have determined that xylitol boosts dental health and helps prevent tooth decay.
One of the leading risk factors for tooth decay is an oral bacteria called Streptococcus mutans.

This is the bacteria most responsible for plaque.
Although some plaque on your teeth is normal, excess plaque encourages your immune system to attack the bacteria in it.
This can lead to inflammatory gum diseases like gingivitis.

These oral bacteria feed on glucose from food, but they can not use xylitol.
As such, replacing sugar with xylitol reduces the available fuel for the harmful bacteria.
While these bacteria cannot use xylitol for fuel, they still ingest it.

After absorbing xylitol, they are unable to take up glucose — meaning that their energy-producing pathway is clogged and they end up dying.
In other words, when you chew gum with xylitol or use it as a sweetener, the harmful bacteria in your mouth starve to death.
In one study, xylitol-sweetened chewing gum reduced levels of bad bacteria by 27–75%, while friendly bacteria levels remained constant.



XYLITOL REDUCES EAR AND YEAST INFECTIONS:
Your mouth, nose and ears are all interconnected.
Therefore, bacteria that live in the mouth can end up causing ear infections — a common problem in children.
It turns out that xylitol can starve some of these bacteria in the same way that it starves plaque-producing bacteria.

One study in children with recurring ear infections observed that daily usage of xylitol-sweetened chewing gum reduced their infection rate by 40%.
Xylitol also fights the yeast Candida albicans, which can lead to candida infections.
Xylitol reduces the yeast’s ability to stick to surfaces, thereby helping prevent infection



OTHER POTENTIAL HEALTH BENEFITS OF XYLITOL:
Collagen is the most abundant protein in your body, found in large amounts in skin and connective tissues.
Some studies in rats link xylitol to increased production of collagen, which may help counteract the effects of aging on your skin.
Xylitol also feeds the friendly bacteria in your gut, acting as a soluble fiber and improving your digestive health



DOES XYLITOL HAVE CALORIES?
Although Xylitol has a sweet taste, which is why it’s used as a sugar substitute, it doesn’t contain any cane/table sugar and also has fewer calories than traditional sweeteners.

Xylitol’s about 40 percent lower in calories than regular sugar, providing about 10 calories per teaspoon.
(Sugar provides about 16 per teaspoon.)
Xylitol has a similar appearance to sugar and can be used in the same ways.



STRUCTURE, PRODUCTION, COMMERCE OF XYLITOL:
Xylitol is one of three 5-carbon sugar alcohols.
The others are arabitol and ribitol.
These three compounds differ in the stereochemistry of the three secondary alcohol groups.



HISTORY OF XYLITOL:
Emil Fischer, a German chemistry professor, and his assistant Rudolf Stahel isolated a new compound from beech wood chips in September 1890 and named it Xylit, the German word for xylitol.
The following year, the French chemist M.G. Bertrand isolated xylitol syrup by processing wheat and oat straw.
Sugar rationing during World War II led to an interest in sugar substitutes.
Interest in xylitol and other polyols became intense, leading to their characterization and manufacturing methods.



POTENTIAL HEALTH BENEFITS OF XYLITOL:
1. May Help Improve Dental Health:
Although consuming this ingredient can put you at risk for digestive issues, one potential xylitol benefit seems to be its ability to improve oral health.
This appears to be widely held by most health care professionals and dentists.

In fact, the dental community is one of its biggest supports of xylitol because of its reported ability to prevent cavities.
For example, according to a study published in the Journal of Dental Education, “The replacement of sucrose with sorbitol and xylitol may significantly decrease the incidence of dental caries.”

Research tells us that xylitol may be able to help prevent cavities because it cannot be metabolized by plaque bacteria, unlike other forms of sugar.
This means that Xylitol can have beneficial effects on the oral flora (microbes living in your mouth) not shared by other sweeteners.
Because mouth bacteria can’t use xylitol as a source of energy, it may help prevent tooth decay (such as bacteria like Streptococcus mutans) and the buildup of plaque on your teeth.

Interesting, there are conflicting reports, and we cannot jump to the conclusion that xylitol is completely effective at keeping cavities at bay. In the words of a frequently cited review in the journal Caries Research, “There is no evidence for a caries-therapeutic effect of xylitol,”which makes us wonder what side of the coin to believe.


2. Can Be Used While on a Low-Sugar/Low-Carb Diet:
This ingredient doesn’t contain any fructose and does not stimulate the release of insulin from the pancreas.
This means it will not cause a significant impact on your blood sugar and insulin levels.

*Can you use xylitol on the keto diet?
Yes — among other low-calorie sweeteners, such as stevia, it’s found in many low-carb products since it can help keep sugar intake low and works as a keto sweetener.

While xylitol does provide a few carbohydrates and a low amount of calories, these shouldn’t interfere with your ability to stay in ketosis, assuming you don’t eat it in large amounts.



HIGHLIGHTS OF XYLITOL:
*Xylitol is a type of carbohydrate called a sugar alcohol, or polyol.
*Xylitol occurs naturally in many fruits and vegetables.
*Xylitol is also commercially produced from birch bark and corn cob for use as a sweetener.
*Xylitol is a common ingredient in sugar-free chewing gum.
*Xylitol safety is confirmed by the U.S. Food and Drug Administration and the World Health Organization.
*Xylitol is known to inhibit the growth of oral bacteria (mutans streptococci) in plaque and saliva.



THE BASICS OF XYLITOL:
Xylitol (pronounced Zy-Li-Tall) is a type of carbohydrate called a sugar alcohol, or polyol.
They are water-soluble compounds that occur naturally in many fruits and vegetables.
Xylitol is also commercially produced from birch bark and corn cob for use as a sweetener to replace calories from carbohydrates and sugars.

Xylitol has been approved for use in food by the Food and Drug Administration (FDA) since 1963.
The name Xylitol comes from the word “xylose” or “wood sugar” because it was first made from birch trees.
Xylitol has a cooling sensation in the mouth when consumed.
As a result, xylitol is a preferred ingredient in sugar-free chewing gum and other oral health products like breath mints, mouthwash and toothpaste.



XYLITOL AND HEALTH:
Xylitol has a chemical structure similar to sugar, but has fewer calories; while sugar has about 4 calories per gram, xylitol has just 2.4.
Although it’s lower in calories, xylitol is equal to the sweetness of sugar.
This makes xylitol unique because most sugar alcohols are not as sweet as sugar.

Xylitol is known to inhibit the growth of oral bacteria (mutans streptococci) in plaque and saliva.
The act of chewing gum promotes the flow of saliva, which naturally protects teeth from cavity-causing bacteria.
Based on a large amount of scientific evidence both the American Dental Association and the FDAhave recognized xylitol as beneficial to oral health.

Other health benefits of xylitol stem from its differences in chemical structure compared to sugar.
Unlike sugar, xylitol is slowly and incompletely absorbed in the small intestine.
This makes it and other sugar alcohols helpful for people with diabetes.
Once absorbed, it can be used for energy while using little or no insulin, which means the impact on blood sugar is minimal.

Bacteria in the large intestine ferment any unabsorbed xylitol that passes through the small intestine.
Because of this, overconsumption can produce abdominal gas and discomfort.
For those following a low Fermentable Oligosaccharides Disaccharides Monosaccharides And Polyols (FODMAP) diet, food sources of xylitol are monitored because xylitol is a type of polyol.



WHAT IS XYLITOL MADE FROM?
Xylitol is a crystalline alcohol and a derivative of xylose — a crystalline aldose sugar that is not digestible by the bacteria in our digestive systems.
Xylitol’s usually produced in a lab from xylose but also comes from the bark of the birch tree, the xylan plant, and in very small quantities is found in some fruits and vegetables (like plums, strawberries, cauliflower and pumpkin).



EFFECT OF XYLITOL:
Xylitol serves many important functions for oral and general health.
These include the following:
Antimicrobial properties help prevent tooth decay by inhibiting bacteria, particularly Streptococcus mutans (the oral bacteria that causes cavities) and plaque from sticking to teeth.

Regular use by mothers reduces the transmission of Streptococcus mutans to children by up to 80 percent during the first two years.
Enhances mineral absorption in tooth enamel, increasing its strength.
Consistently using small amounts of xylitol stimulates saliva flow and increases saliva’s buffering capacity and protective factors.

Increased saliva production is especially important for people suffering from dry mouth (xerostomia) due to illness, aging or drug side effects.
Supplemental use of xylitol, in combination with other dental therapies, can reduce the incidence of new tooth decay and arrest existing dental caries.

Chewing xylitol-sweetened gum can help prevent ear infections; the act of chewing/swallowing helps to remove earwax and clear the middle ear (between the eardrum and cochlea), while the presence of xylitol prevents the growth and attachment of bacteria in the Eustachian tubes (tubes that connect the nose and ear).

Using a xylitol nasal spray can significantly reduce the incidence of sinus infections, allergies and asthma.
Additionally, xylitol has been found to increase the activity of white blood cells involved in fighting bacteria and thus may help build immunity, protect against chronic degenerative disease and have anti-aging benefits.

Xylitol has been proven effective in inhibiting Candida albicans, a serious yeast condition, and other harmful bacteria, including H. pylori, which is implicated in gum disease, bad breath, ulcers and stomach cancer.
Using xylitol instead of sugar and/or refined carbohydrate foods may help to lower the risk of polycystic ovarian syndrome (a condition that disrupts or stops the ovulation cycle), ovarian cysts, fibroids, endometriosis, premenstrual syndrome and possibly breast cancer.



HOW XYLITOL WORKS?
Eating sugar causes tooth decay by creating an acidic condition in the mouth.
Acidity strips minerals from tooth enamel, causing it to weaken and be more vulnerable to bacteria, leading to tooth decay or demineralization.
Ordinarily, saliva bathes the mouth with an alkaline solution that neutralizes acidity and remineralizes teeth.

Saliva also washes away leftover food particles and helps with digestion.
However, when saliva turns acidic because of too many sweets, oral bacteria take over.
These bacteria, combined with carbohydrate waste, stick to the teeth and tongue, keeping the acid close to the teeth where it erodes tooth enamel.

Xylitol is non-fermentable and cannot be converted to acids by oral bacteria.
As a result, Xylitol helps restore a proper alkaline/acid balance in the mouth.
This alkaline environment reduces the time teeth are exposed to acids while also starving bacteria.



HEALTH BENEFITS OF XYLITOL:
Xylitol can be used to achieve the following health benefits:

1. Promoting weight loss
Because it has a low glycemic index (only 8), xylitol can help to regulate blood sugar levels and help to manage hunger throughout the day.
Xylitol can prevent the formation of fat cells, which can reduce the risk for weight gain.

One teaspoon of xylitol only has 8 calories, making it a great option to sweeten foods in comparison to higher calorie sweeteners, like honey or sugar.

2. Preventing cavities
Xylitol can help to prevent cavities, as it inhibits the growth of Streptococcus mutans.
This is the main bacteria responsible for causing tooth infections.

3. Helping to manage diabetes
Because it has a low glycemic index, xylitol can keep blood sugar levels within normal ranges.
This can be beneficial for patients with hyperglycemia and diabetes.

4. Preventing ear infections
Xylitol can help to prevent ear infections by combating other microorganisms that live in the mouth and the ears, like Candida albicans.



DIFFERENCE BETWEEN XYLITOL AND STEVIA:
Stevia is a natural sweetener that is extracted from the Stevia Rebaudiana Bertoni plant.
It can be found in powder, granulated or liquid form.

Stevia can also sweeten food two to three hundred more times than common sugar, and has an additional bitter taste, which can alter the taste of some foods.
Xylitol is obtained from the fruit and vegetable fibers, and is usually available in granulated form.
Xylitol has the same sweetness level as sugar and has a mild taste that does not alter the taste of foods when used.



HOW TO USE XYLITOL:
This sweetener's properties remain intact even at high temperatures, which is why xylitol can be used to sweeten juices, teas, coffee, cookies, cakes or pies.
It is important to remember that one teaspoon of xylitol contains the same sweetness as one teaspoon of sugar.



RECOMMENDED DOSE OF XYLITOL:
There is currently no daily recommended dose of xylitol per day.
However, you should not exceed 60 g of xylitol per day.



COMPARISON TO OTHER SUGAR SUBSTITUTES:
Xylitol has some similarities to other “natural” or alternative sweeteners, including kinds called:
*Erythritol
*Isomalt
*Lactitol
*Maltitol
*Mannitol
*Sorbitol

*Xylitol vs. Stevia
Stevia is an herbal plant that belongs to the Asteraceae family.
The stevia plant has been used for over 1,500 years by the Guaraní people of Brazil and Paraguay.



IS XYLITOL OR STEVIA BETTER?
While the message is a little cloudy about xylitol side effects, of the innumerable scientific papers referencing stevia, one message is clear:
It is safe and effective.
As stated in a critical evaluation, stevia “has a low glycemic index and, in the doses tested, is not cytotoxic nor has acute or chronic effect on blood sugar, which makes it a safe sweetener.”

*Xylitol vs. Erythritol
Both of these products are sugar alcohols (also called reduced-calorie sweeteners).
The main difference is that xylitol does contain some calories (it’s not zero-calorie like erythritol) but less than sugar.
Xylitol also has a small impact on blood sugar levels, while erythritol does not have any impact, making it more suitable for diabetics.
Because xylitol can cause diarrhea in some people, especially when used in large amounts, this is one reason why some people prefer erythritol.



IS XYLITOL BAD FOR YOU?
Xylitol is a sweetener that is generally considered to be safe for use.
Xylitol can be used by diabetics, pregnant women and breastfeeding women.



PHYSICAL and CHEMICAL PROPERTIES of XYLITOL:
Chemical formula: C5H12O5
Molar mass: 152.146 g/mol
Density: 1.52 g/cm3
Melting point: 92 to 96 °C (198 to 205 °F; 365 to 369 K)
Boiling point: 345.39 °C (653.70 °F; 618.54 K) (predicted value using Adapted Stein & Brown method)
Solubility in water: Approximately 100 g/L



FIRST AID MEASURES of XYLITOL:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of XYLITOL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of XYLITOL:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of XYLITOL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of XYLITOL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of XYLITOL:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

XYLITYL PHOSPHATE
XYLOSE N° CAS : 58-86-6 Nom INCI : XYLOSE Nom chimique : D-Xylose N° EINECS/ELINCS : 200-400-7 Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit Agent d'entretien de la peau : Maintient la peau en bon état
XYLOSE
ZINC N° CAS : 7440-66-6 Nom INCI : ZINC N° EINECS/ELINCS : 231-175-3 Ses fonctions (INCI) Antioxydant : Inhibe les réactions favorisées par l'oxygène, évitant ainsi l'oxydation et la ranc
ZDBC (ZINC DIBUTYLDITHIOCARBAMATE)
ZDBC (Zinc Dibutyldithiocarbamate) is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
ZDBC (Zinc Dibutyldithiocarbamate) has a role as an antifungal agrochemical.
ZDBC (Zinc Dibutyldithiocarbamate) is a dithiocarbamate salt and a zinc molecular entity.

CAS: 136-23-2
MF: C18H36N2S4Zn
MW: 474.14
EINECS: 205-232-8

Synonyms
(dibutyldithiocarbamato)zinc(ii);accelbz;acetozdbd;bis(dibutylcarbamodithioato-S,S’)-,(T-4)-Zinc;vulkacitldb/c;zimate,butyl;zincbibutyldithiocarbamate;Zinc N,N-dibutyldithiocarbamate
Zinc dibutyldithiocarbamate;(Dibutyldithiocarbamato)zinc(II); Accel BZ; Aceto ZDBD; Bis(N,N-dibutyldithiocarbamato)zinc; Bis(dibutyldithiocarbamato)zinc; Butazate; Butazate 50-D; Butyl zimate; Butyl ziram; Carbamic acid, dibutyldithio-, zinc complex; Carbamodithioic acid, dibutyl-, zinc salt; Dibutyldithiocarbamic acid zinc salt; Nocceler BZ; Soxinol BZ; Vulcacure; Vulcacure ZB; Vulkacit LDB; Vulkacit LDB/C; Zimate, butyl; Zinc N,N-dibutyldithiocarbamate; Zinc bis(dibutyldithiocarbamate); Zinc dibutyldithiocarbamate; Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-; Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-; Zinc, bis(dibutyldithiocarbamato)-; [ChemIDplus] ZDBC; [HSDB];136-23-2;Zinc(II) Dibutyldithiocarbamate;Zinc bis(dibutyldithiocarbamate);zinc;N,N-dibutylcarbamodithioate;DTXSID0021462;Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-;DTXCID501462;Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-;CAS-136-23-2;Bis(dibutyldithiocarbamato)zinc;zinc bis(dibutylcarbamodithioate);HNM5J934VP;SCHEMBL35745;dibutyldithiocarbamate zinc salt;ZINCDIBUTYLDITHIOCARBAMATE;CHEMBL2373108;BOXSVZNGTQTENJ-UHFFFAOYSA-L;CHEBI:144323;NSC-3880;Tox21_113038;Tox21_202601;NSC-36548;AKOS015839728;zinc bis(dibutylthiocarbamoyl)disulfide;zinc bis(dibutyldithiocarbamoyl)disulfide;Dibutyldithiocarbamic Acid Zinc(II) Salt;NCGC00188440-01;NCGC00260149-01;zinc bis(dibutyldithiocarbamoyl)disulphide;ZINC DIBUTYLDITHIOCARBAMATE [INCI];CS-0152117;D0227;NS00079390;E81950;ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-
;ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB];(T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc;Q27280015

ZDBC (Zinc Dibutyldithiocarbamate) contains a dibutyldithiocarbamate and a zinc(2+).
ZDBC (Zinc Dibutyldithiocarbamate) is functionally related to a dibutyldithiocarbamic acid.
White powder; pleasant odor.
Soluble in carbon disulfide, benzene, and chloroform; insoluble in water.
ZDBC (Zinc Dibutyldithiocarbamate) is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
ZDBC (Zinc Dibutyldithiocarbamate) has a role as an antifungal agrochemical.
ZDBC (Zinc Dibutyldithiocarbamate) is a dithiocarbamate salt and a zinc molecular entity.
ZDBC (Zinc Dibutyldithiocarbamate) contains a dibutyldithiocarbamate and a zinc(2+).
ZDBC (Zinc Dibutyldithiocarbamate) is functionally related to a dibutyldithiocarbamic acid.

ZDBC (Zinc Dibutyldithiocarbamate) is a dermatological sensitizer and allergen.
Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.
ZDBC (Zinc Dibutyldithiocarbamate) is a Standardized Chemical Allergen.
The physiologic effect of ZDBC (Zinc Dibutyldithiocarbamate) is by means of Increased Histamine Release, and Cell-mediated Immunity.
ZDBC (Zinc Dibutyldithiocarbamate) is a chemical compound that forms a complex with fatty acids.
ZDBC (Zinc Dibutyldithiocarbamate) is used as an absorbent and sample preparation agent in uv spectroscopy.
ZDBC (Zinc Dibutyldithiocarbamate) can also cause allergic reactions and is toxic to cells in the presence of calcium stearate.
This chemical is found in reaction solutions, where it reacts with hydrochloric acid and boron nitride to form ZDBC (Zinc Dibutyldithiocarbamate).
ZDBC (Zinc Dibutyldithiocarbamate) has shown growth factor-like properties and was shown to enhance the rate of cell growth on V79 cells when combined with polyene.

ZDBC (Zinc Dibutyldithiocarbamate) Chemical Properties
Melting point: 104-110°C
Boiling point: 318℃[at 101 325 Pa]
Density: 1,21 g/cm3
Vapor pressure: 0Pa at 25℃
Storage temp.: Inert atmosphere,Room Temperature
Solubility: Insoluble in water
Form: solid
Specific Gravity: 1.21
Color: White
Odor: wh. powd., pleasant odor
Water Solubility: 100μg/L at 25℃
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChIKey: BOXSVZNGTQTENJ-UHFFFAOYSA-L
LogP: 2.16 at 25℃
CAS DataBase Reference: 136-23-2(CAS DataBase Reference)
EPA Substance Registry System: ZDBC (Zinc Dibutyldithiocarbamate) (136-23-2)

Uses
Accelerator for latex dispersions and cements, etc; ultra-accelerator for lubricating oil additive.
ZDBC (Zinc Dibutyldithiocarbamate) is a rubber chemical used as a vulcanization accelerator.
ZDBC (Zinc Dibutyldithiocarbamate) can also be found in paints, glue removers and anticorrosives.
ZDBC (Zinc Dibutyldithiocarbamate) was contained in the "carba-mix".
ZDBC (Zinc Dibutyldithiocarbamate) is used as activator; antidegradant; accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethyJene-propylene-diene terpolymers.

ZDBC (Zinc Dibutyldithiocarbamate) is used as secondary ultra accelerator for thiazole and sulfenamide cure systems in general purpose polymers (NR, SBR, IIR, EPDM).
ZDBC (Zinc Dibutyldithiocarbamate) can be used as a primary accelerator in specialty applications as well as in latex.
In latex applications ZDBC (Zinc Dibutyldithiocarbamate) is mainly used in transparent goods and in prevulcanized latex.
An additional application is as an antioxidant in adhesive systems.
ZDBC gives faster cures than ZDEC or ZDMC.
ZDMC (ZINC DIMETHYLDITHIOCARBAMATE)
A dithiocarbamate salt that is the ZDMC (Zinc dimethyldithiocarbamate).
ZDMC (Zinc dimethyldithiocarbamate) is a broad-spectrum fungicide and bird and animal repellent that is also used to accelerate the vulcanisation of rubber.
ZDMC (Zinc dimethyldithiocarbamate) is a rubber vulcanization accelerator of the dithiocarbamate group.

CAS: 137-30-4
MF: C6H12N2S4Zn1
MW: 305.829
EINECS: 205-288-3

Synonyms
THIONIC;POMARSOL Z;POMARSOL Z(R);MILBAM(R);AAVOLEX;KARBAM WHITE(R);FUCLASIN;FUCLASINE(R)
;137-30-4;Dimethyldithiocarbamate zinc salt;zinc;N,N-dimethylcarbamodithioate;DTXCID301464;DTXSID0021464;CHEBI:79736;zinc bis(dimethylcarbamodithioate);CAS-137-30-4;SCHEMBL22004;Zinc Dimethyl Dithio Carbamate;Bis(dimethyldithiocarbamato)zinc;bis(dimethylcarbamothioylthio)zinc;Bis-dimethyldithiocarbamate de zinc;Zinc dimethyldithiocarbamate, 97%;Tox21_201910;Tox21_300503;MFCD00064797;AKOS015960834
;Bis(dimethylcarbamodithioato-S,S')zinc;Zinc bis(dimethylthiocarbamoyl)disulfide;NCGC00254404-01;NCGC00259459-01;Ziram, PESTANAL(R), analytical standard;Zinc bi(dimethyldithiocarbamoyl)disulphide;Zinc dimethyldithiocarbamate, purum, >=97.0% (KT);(T-4)-bis(dimethylcarbamodithioato-kappaS,kappaS')zinc

ZDMC (Zinc dimethyldithiocarbamate) is a coordination complex of zinc with dimethyldithiocarbamate.
ZDMC (Zinc dimethyldithiocarbamate) is a pale yellow solid that is used as a fungicide, the sulfur vulcanization of rubber, and other industrial applications.
ZDMC (Zinc dimethyldithiocarbamate) is a complex of zinc and dimethyl dithiocarbamate, which is a light yellow solid, it is commonly used as a fungicide, also for the vulcanization of rubber and other industrial applications.
ZDMC (Zinc dimethyldithiocarbamate) can be prepared by mixing and stirring dimethylamine hydrochloride, sodium hydroxide and carbon disulfide, and then reacting with zinc sulfate in water.

ZDMC (Zinc dimethyldithiocarbamate) Chemical Properties
Melting point: 248-257 °C(lit.)
Boiling point: 335.83℃[at 101 325 Pa]
Density: 1.66
Vapor pressure: Storage temp.: APPROX 4°C
Solubility: DMSO (Sparingly), Methanol (Sparingly)
Form: Powder
Specific Gravity: 1.71
Color: White
Odor: odorless when pure
Water Solubility: 0.0065 g/100 mL
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
Merck: 14,10172
BRN: 3707008
InChIKey: DUBNHZYBDBBJHD-UHFFFAOYSA-L
LogP: 1.65 at 20℃
CAS DataBase Reference: 137-30-4(CAS DataBase Reference)
IARC: 3 (Vol. Sup 7, 53) 1991
NIST Chemistry Reference: ZDMC (Zinc dimethyldithiocarbamate) (137-30-4)
EPA Substance Registry System: ZDMC (Zinc dimethyldithiocarbamate) (137-30-4)

White and odorless when pure.
Almost insoluble inwater; soluble in acetone, carbon disulfide, chloroform, dilute alkalies, and concentrated hydrochloric acid.

Uses
ZDMC (Zinc dimethyldithiocarbamate) is a protective fungicide applied to foliage to control diseases on pome fruit, stone fruit, nuts, vines, vegetables and ornamentals.
ZDMC (Zinc dimethyldithiocarbamate) is used to control scab in apples and pears and Monilia, Alternaria, Septoria, peach leaf curl, shot hole, rusts, black rot and anthracnose.
ZDMC (Zinc dimethyldithiocarbamate) is also used as a wildlife repellent, smeared as a paste onto tree trunks or sprayed onto ornamentals, dormant fruit trees and other crops.
ZDMC (Zinc dimethyldithiocarbamate) is a member of a class of dithiocarbamates, and has been used in agriculture as a fungicide and in the rubber industry as a vulcanization accelerator.
Rubber vulcanization accelerator; agricultural fungicide.

Known as ZDMC (Zinc dimethyldithiocarbamate) in agriculture, it was introduced in the United States in 1960 as a broad-spectrum fungicide.
ZDMC (Zinc dimethyldithiocarbamate) was used to address scab on apples and pears, leaf curl in peaches, and anthracnose and blight in tomatoes.
In 1981, additional uses for ZDMC (Zinc dimethyldithiocarbamate) were approved, including the prevention of leaf blight and scab on almonds, shot-hole in apricots, brown rot and leaf spot in cherries, and scab and anthracnose in pecans.
ZDMC (Zinc dimethyldithiocarbamate) also began to be used on residential ornaments as a bird and mammal repellent.
As a protectant fungicide, ZDMC (Zinc dimethyldithiocarbamate) is active on the plant’s surface where it forms a chemical barrier between the plant and a fungus.
A protectant fungicide is not absorbed into the plant and must be applied prior to infection. ZDMC (Zinc dimethyldithiocarbamate) can either be directly sprayed on to a plant’s leaf or it can be used as a soil and seed treatment.
The top five crops ZDMC (Zinc dimethyldithiocarbamate) is used on are: almonds, peaches, nectarines, pears, and table and raisin grapes.
Alternatively, ZDMC (Zinc dimethyldithiocarbamate) is used as an additive ingredient in industrial adhesives, caulking, and paint.
ZDMC (Zinc dimethyldithiocarbamate) also serves as a bird and mammal repellent on outdoor ornamental items.

ZDMC (Zinc dimethyldithiocarbamate) for controlling Apple rot, black spot, powdery mildew, etc, good dispersion in rubber, so that the mechanical properties of rubber products is good, suitable for tires, tape, etc.
ZDMC (Zinc dimethyldithiocarbamate) can inhibit and prevent diseases caused by a variety of fungi, stimulate growth and promote early maturity.
For the prevention and control of rice blast, Miscanthus disease, wheat rust, powdery mildew, potato late blight, black spot, cucumber, cabbage, cabbage downy mildew, tomato anthracnose, early blight, melon anthracnose, tobacco leaf blight, apple rot, anthracnose, black spot disease, brown spot disease, grape powdery mildew, anthracnose, pear scab, citrus canker, scab disease, etc.
Generally with 65% wettable powder 300~500 times liquid treatment.
Before the onset or early spraying, there is a preventive effect, the onset of the disease every 5 ~ 7d spray 1 times, continuous 2~4 times.
According to different diseases, the dosage and frequency of drug use were different.
fosfomezinc is effective for controlling Apple anthracnose and peach brown rot, and bacterial perforation.
Prevention and Control of white rot of grape, anthracnose, often mixed with the use of Fu Mei.
ZDMC (Zinc dimethyldithiocarbamate) is also used to control cucumber downy mildew, melon anthracnose, potato late blight, Chinese cabbage downy mildew and tomato anthracnose.

Agricultural Uses
Fungicide, Microbiocide, Animal repellant: ZDMC (Zinc dimethyldithiocarbamate) is an agricultural fungicide registered to control fungal diseases on a wide range of crops including stone fruits, pome fruits, nut crops, vegetables and commercially grown ornamentals, and as a soil and seed treatment.
In addition, ZDMC (Zinc dimethyldithiocarbamate) is formulated as a bird and rabbit repellent for outdoor foliar applications to ornamentals.
Registered for use in EU countries .
Registered for use in the U.S.

Chemistry
ZDMC (Zinc dimethyldithiocarbamate) is a prototypical zinc dithiocarbamate, a broad class of coordination complexes with the formulae Zn(R2NCS2)2, where R can be varied.
Such compounds are produced by treating zinc and dithiocarbamate (R2NCS2−), as illustrated with dimethyldithiocarbamate:

2 (CH3)2NCS2− + Zn2+ → Zn((CH3)2NCS2)2
Annually, approximately 1.9 million pounds of the active ziram ingredient are used.
ZDMC (Zinc dimethyldithiocarbamate) is often sold in powder or granule form.
ZDMC (Zinc dimethyldithiocarbamate) complexes degrade thermally to give zinc sulfide.

Structure
Compounds of the type Zn(S2CNR2)2 are dimeric, i.e. their proper formula is [Zn(S2CNR2)2]2. Each Zn center is in a distorted pentacoordinate site, with four Zn-S bonds of 2.3 Å length and one Zn---S interaction >2.8 Å in length.
Mono-zinc derivatives are obtained by adding strong ligands (L) such as amines, which give adducts Zn(S2CNR2)2L.

Ecological effects
The U.S. Environmental Protection Agency has concluded that ziram poses a low toxicity risk to mammals, a moderate risk to birds, and a high risk to aquatic species.
After reviewing studies that investigated the effect of ZDMC (Zinc dimethyldithiocarbamate) on aquatic organisms, the Pesticide Action Network Pesticide Database concluded that its LC50 dose (amount of pesticide that is lethal to 50% of the test organisms within the stated study time) for amphibians places ZDMC (Zinc dimethyldithiocarbamate) in the "highly toxic" category.

Air & Water Reactions
Thio and dithiocarbamates slowly decompose in aqueous solution to form carbon disulfide and methylamine or other amines.
Such decompositions are accelerated by acids.
Insoluble in water.

Reactivity Profile
ZDMC (Zinc dimethyldithiocarbamate) is a dithiocarbamate.
Flammable gases are generated by the combination of thiocarbamates and dithiocarbamates with aldehydes, nitrides, and hydrides.
Thiocarbamates and dithiocarbamates are incompatible with acids, peroxides, and acid halides.
ZDMC (Zinc dimethyldithiocarbamate) is corrosive to iron and copper.
ZDMC (Zinc dimethyldithiocarbamate) is incompatible with strong oxidizing agents and acids.
ZDMC (Zinc dimethyldithiocarbamate) is also incompatible with mercury.

Metabolic Pathway
ZDMC (Zinc dimethyldithiocarbamate) is one of the metal containing dithiocarbamates which generates dimethyldithiocarbamic acid by being cleaved in acidic conditions and in biological media.
The resulting acid is conjugated with glucose and alanine in plants and with glucuronic acid in mammals.
ZDMC (Zinc dimethyldithiocarbamate) is further degraded to dimethylamine and CS2.
An extensive review of the properties of dithiocarbamate pesticides was published by the World Health Organisation from which much of the following information is taken.

Production Method
ZDMC (Zinc dimethyldithiocarbamate) is obtained by reacting sodium dimethyldithiocarbamate with zinc sulfate (or zinc chloride).
The pH of the reaction solution was adjusted to 7 by adding water to be dissolved in sodium fumarate.
5~8, and then with the zinc sulfate, the formation of fumed zinc precipitate, after filtration, drying, grinding to prepare fumed zinc.
The yield was more than 97% and the content was more than or equal to 93%.
Zeliquid LP 2
Lauryl polyethylene glycol ethersulfate with 3 EO, ammonium; salt, butoxy ethanol as solvent; About 50 % Liquid Air entraining agent for concrete and mortars
ZINC
Acetic acid, zinc salt; Acetic acid, zinc(II) salt; Dicarbomethoxyzinc; Zinc Diacetate; cas no: 557-34-6
ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT)
DESCRIPTION:
Zinc 2-mercaptobenzothiazole (ZMBT) can be dispersed easily in water using common dispersing agents.
Zinc 2-mercaptobenzothiazole (ZMBT) can also be used in dry rubber compounds as semi ultra accelerator.


CAS: 155-04-4
European Community (EC) Number: 205-840-3
Molecular Formula: C14H8N2S4Zn
IUPAC Name:zinc;1,3-benzothiazole-2-thiolate


SYNONYMS OF ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
Zinc 2-mercaptobenzothiazole,155-04-4,Bantex,2-Mercaptobenzothiazole zinc salt,OXAF,Zinc 2-benzothiazolethiolate,Zinc 2-mercaptobenzothiazolate,2-MERCAPTOBENZOTHIAZOLEZINCSALT,2(3H)-Benzothiazolethione, zinc salt,Zenite,Zetax,Zenite special,ZINC MERCAPTOBENZOTHIAZOLE,Vulkacit ZM,Hermat Zn-mbt,Pennac ZT,ZnMB,HMM5IX9Q3B,Tisperse MB-58,ZMBT,zinc bis(1,3-benzothiazole-2-thiolate),2,Mercaptobenzothiazole, zinc,Zinc benzothiazolethiolate,USAF GY-7,Zinc mercaptobenzothiazolate,Zinc benzothiazolylmercaptide,Bis(2-benzothiazolylthio)zinc,Mercaptobenzothiazole zinc salt,Zinc benzothiazol-2-ylthiolate,Zinc benzothiazyl-2-mercaptide,Zinc mercaptobenzothiazole salt,Zinc bis(mercaptobenzothiazole),Bis(mercaptobenzothiazolato)zinc,Zinc bis(2-mercaptobenzothiazole),Zinc, bis(2-benzothiazolethiolato)-,2-Benzothiazolethiol, zinc salt (2:1),Caswell No. 917,NSC-285168,UNII-HMM5IX9Q3B,2-Benzothiazolethiol zinc salt,HSDB 5419,Bis(benzothiazole-2-thiolato)zinc,EINECS 205-840-3,EPA Pesticide Chemical Code 051705,EC 205-840-3,SCHEMBL410383,DTXSID6020808,zinc;1,3-benzothiazole-2-thiolate,Zinc(II) benzo[d]thiazole-2-thiolate,NSC 285168,ZINC MERCAPTOBENZOTHIAZOLE [HSDB],CS-0188512,Z0033,2(3H)-Benzothiazolethione, zinc salt (2:1),E77122,zinc(2+) bis((1,3-benzothiazol-2-yl)sulfanide),Q27094435 , 2(3H)-Benzothiazolethione,zinc salt (2:1);2(3H)-Benzothiazolethione,zinc salt;Benzothiazole,2-mercapto-,zinc salt;2-Mercaptobenzothiazole zinc salt;OXAF;Pennac ZT;Tisperse MB 58;Zenite;Zenite Special;Zetax;Zinc mercaptobenzothiazolate;Zinc 2-mercaptobenzothiazole;Zinc mercaptobenzothiazole;ZMBT;Zinc benzothiazolylmercaptide;Zinc 2-benzothiazolethiolate;Mercaptobenzothiazole zinc salt;Bis(2-benzothiazolylthio)zinc;Zinc benzothiazol-2-ylthiolate;Zinc mercaptobenzothiazole salt;Zinc bis(mercaptobenzothiazole);Bis(mercaptobenzothiazolato)zinc;Zinc bis(2-mercaptobenzothiazole);Zinc benzothiazolethiolate;2-Benzothiazolethiol zinc salt;Hermat Zn-MBT;Vulkacit ZM;Bis(benzothiazole-2-thiolato)zinc;Soxinol MZ;Nocceler MZ;Sanceler MZ;Perkacit ZMBT;MZ;Accelerator MZ;Curekind ZMBT 15;Zinc 2(3H)-benzothiazolethione;96380-91-5;12564-44-2;16529-10-5, ZMBT; Bantex; Zinc Salt of 2-Mercaptobenzothiazole, Zetax; 2(3H)-Benzothiazolethione, zinc salt; Benzothiazolethiol, zinc salt; ZNMB; Zinc Bis(mercaptobenzothiazole); Benzothiazolethione, zinc salt; Zinc 2-mercaptobenzothiazolate; Zinc benzothiazolethiolate; Zinc benzothiazolylmercaptide; Zinc Bis(mercaptobenzothiazole); Zinc mercaptobenzothiazole;



Sulfur combines with nearly all elements.
Sulfur forms ring and chain structures as it is the second only to carbon in exhibiting catenation.
The 8-membered ring and shorter chain structure of sulfur molecule is important in vulcanization process which individual polymers are linked to other polymer molecules by atomic bridges.


This process produces thermoset materials which are cross-linked and irreversible substances.
The term thermoplastic is for high molecular weight polymers which can undergo melting-freezing cycle.
Thermosets are not melted and re-molded on heating after cured.

The split of sulfur 8-membered ring structure into shorter chains provides rubber vulcanization process.
The split are liked with cure sites (some of the solid bonds in the molecule) on rubber molecules, resulting in forming sulfur bridges typically between 2 and 10 atoms long.

Vulcanization makes rubber harder, more durable and more resistant to heating, aging and chemical attacks.
The number of sulfur atoms in the sulfur bridges varies physical properties of the end products.
Short bridges containing one or two sulfur atoms offer heat resistance and long bridges offer flexible property.

Vulcanization can also be accomplished with certain peroxides, gamma radiation, and several other organic compounds.
The principal classes of peroxide cross-linking agents are dialkyl and diaralkyl peroxides, peroxyketals and peroxyesters.
Other vulcanizing agents include amine compounds for the cross-linking of fluorocarbon rubbers, metal oxides for chlorine-containing rubbers (notably zinc oxide for chloroprene rubber) and phenol-formaldehyde resins for the production of heat-resistant butyl rubber vulcanizates.

Accelerator, in the rubber industry, is added with a curing agent to speed the vulcanization.
Accelerators contain sulfur and nitrogen like derivatives of benzothiazole and thiocarbanilides.
The popular accelerators are sulfenamides (as a delayed-action accelerators), thiazoles, thiuram sulfides, dithocarbamates and guanidines.


There are some types of rubber accelerators.
They are used in combination with each other in accordance with vulcanizing and/or acid-base conditions.
Some examples classified by chemical structure are as below;

Thiazole
• 2-Mercaptobenzothiazole (CAS #: 149-30-4)
• Dibenzothiazole disulfide (CAS #: 120-78-5)
• 2-Mercaptobenzothiazole Zinc salt (CAS #: 155-04-4)


Sulphenamide
• N-Cyclohexyl-2-benzothiazole sulfenamide (CAS #: 95-33-0)
• N-Oxydienthylene-2-benzothiazole sulfenamide (CAS #: 102-77-2)
• N-tert-butyl-2-benzothiazyl sulfenamide (CAS #: 95-31-8)


Guanidine
• Diphenyl guanidine (CAS #: 102-06-7)
• Di-o-tolylguanidine (CAS #: 97-39-2)


Thiuram
• Tetramethyl thiuram disulfide (CAS #: 137-26-8)
• Tetraethyl thiuram disulfide (CAS #: 97-77-8)
• Tetramethyl thiuram monosulfide (CAS #: 97-74-5)
• Isobutyl thiuram disulfide (CAS #: 3064-73-1)
• Tetrabenzylthiuram disulfide (CAS #: 10591-85-2)
• Dipentamethylene thiuramtetrasulfide (CAS #: 120-54-7)


Dithiocarbamate
• Zinc dimethyl dithiocarbamate (CAS #: 137-30-4)
• Zinc diethyl dithiocarbamate (CAS #: 14324-55-1)
• Zinc dibutyl dithiocarbamate (CAS #: 136-23-2)
• Zinc N-ethyl-dithiocarbamate (CAS #: 14634-93-6)
• Zinc dibenzyl dithiocarbamate (CAS #: 14726-36-4)
• Copper dimethyl dithiocarbamate (CAS #: 137-29-1)


Thiourea
• Ethylene thiourea (CAS #: 96-45-7)
• N,N'-Diethylthiourea (CAS #: 105-55-5)
• N-N'-Diphenylthiourea (CAS #: 102-08-9)











APPLICATIONS OF ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
Zinc 2-mercaptobenzothiazole (ZMBT) is a semi-ultrafast accelerator widely used in NR/SBR latex compounds along with Qureacc ZDC/ZDBC.
Zinc 2-mercaptobenzothiazole (ZMBT) improves state of cure in NR based compounds even at 120oC and also improves ageing properties.

Zinc 2-mercaptobenzothiazole (ZMBT) can be dispersed easily in water using common dispersing agents.
Zinc 2-mercaptobenzothiazole (ZMBT) can also be used in dry rubber compounds as semi ultra accelerator.
Zinc 2-mercaptobenzothiazole (ZMBT) in combination with Qureacc ZDC at 1 phr levels is widely used in NR/SBR latex compounds for the manufacture of latex threads, foams and dipped goods.

It's main application is in sulfur cured latex as a secondary accelerator in combination with Zinc Diethyldithiocarbamate or Zinc Dimethyldithiocarbamate.
Higher moduli in latex films are obtained than Dithiocarbamates alone and a better compression set resistance in latex foam can be achieved without increasing the cure time.
Zinc 2-mercaptobenzothiazole (ZMBT) is used also as an fast accelerator in dry rubber applications (almost similar to 2-Mercaptobenzothiazole, but with a slight scorch improvement).










USES OF ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
The zinc salt of 2-thiol benzothiazole has the characteristics of fast vulcanization acceleration, low vulcanization flatness and no early vulcanization during mixing.
Zinc 2-mercaptobenzothiazole (ZMBT) is widely used in the rubber processing industry and is an indispensable high-efficiency rubber for natural rubber and synthetic rubber.
Zinc 2-mercaptobenzothiazole (ZMBT) is used as Vulcanization accelerator.




CHEMICAL AND PHYSICAL PROPERTIES OF ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT)
Molecular Weight
397.9 g/mol
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Rotatable Bond Count
0
Exact Mass
395.886175 g/mol
Monoisotopic Mass
395.886175 g/mol
Topological Polar Surface Area
84.3Ų
Heavy Atom Count
21
Formal Charge
0
Complexity
129
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
3
Compound Is Canonicalized
Yes
Melting point, 330 °C
Density, 1.7 g/cm3(Temp: 25 °C)
storage temp., Refrigerator
solubility, Acidic Methanol (Slightly, Heated)
form, Solid
pka, 7.03[at 20 ℃]
color, White to Off-White
Water Solubility, 20.6mg/L at 20℃
LogP, 2.42 at 20℃
Molecular Weight:
397.88
Exact Mass:
395.886169
EC Number:
205-840-3
UNII:
HMM5IX9Q3B
DSSTox ID:
DTXSID6020808
Color/Form:
LIGHT YELLOW POWDER
HScode:
2934999090
PSA:
132.86000
XLogP3:
5.70290
Appearance:
DryPowder; Liquid
Density:
1.7 g/cm3 @ Temp: 25 °C
Melting Point:
330 °C
Boiling Point:
281.3ºC at 760 mmHg
Toxicity:
Oral-rat LD50: 540 mg/kg; Abdominal cavity-mouse LD50: 200 mg/kg
Flammability characteristics:
Flammable; burning produces toxic nitrogen oxides, sulfur oxides and zinc oxide fumes
Molecular Weight:397.9
Hydrogen Bond Acceptor Count:6
Exact Mass:395.886175
Monoisotopic Mass:395.886175
Topological Polar Surface Area:84.3
Heavy Atom Count:21
Complexity:129
Covalently-Bonded Unit Count:3
Compound Is Canonicalized:Yes
Molecular Formula, C14H8N2S4Zn
Molar Mass, 397.88
Density, 1.7 g/cm3(Temp: 25 °C)
Melting Point, 330 °C
Water Solubility, 20.6mg/L at 20℃
Solubility, Acidic Methanol (Slightly, Heated)
Appearance, Solid
Color, White to Off-White
pKa, 7.03[at 20 ℃]
Storage Condition, Refrigerator
Use, Used as natural rubber, General synthetic rubber and latex accelerator



SAFETY INFORMATION ABOUT ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT)
Zinc 2-Mercaptobenzothiazole (ZMBT) is a white or light yellow powder with light bitter taste.
Zinc 2-Mercaptobenzothiazole (ZMBT) can be used as an accelerator for natural rubber, synthetic rubber and latex.


CAS Number: 155-04-4
EC Number: 205-840-3
MDL Number: MFCD00072234
Class: Synthetic Rubber Ingredients
Molecular Formula: C14H8N2S4Zn



SYNONYMS:
Zinc 2-mercaptobenzothiazole, 155-04-4, Bantex, 2-Mercaptobenzothiazole zinc salt, OXAF, Zinc 2-benzothiazolethiolate, Zinc 2-mercaptobenzothiazolate, 2-MERCAPTOBENZOTHIAZOLEZINCSALT, 2(3H)-Benzothiazolethione, zinc salt, Zenite, Zetax, Zenite special, ZINC MERCAPTOBENZOTHIAZOLE, Vulkacit ZM, Hermat Zn-mbt, Pennac ZT, ZnMB, HMM5IX9Q3B, Tisperse MB-58, ZMBT, zinc bis(1,3-benzothiazole-2-thiolate), 2-Mercaptobenzothiazole, zinc, Zinc benzothiazolethiolate, USAF GY-7, Zinc mercaptobenzothiazolate, Zinc benzothiazolylmercaptide, Bis(2-benzothiazolylthio)zinc, Mercaptobenzothiazole zinc salt, Zinc benzothiazol-2-ylthiolate, Zinc benzothiazyl-2-mercaptide, Zinc mercaptobenzothiazole salt, Zinc bis(mercaptobenzothiazole), Bis(mercaptobenzothiazolato)zinc, Zinc bis(2-mercaptobenzothiazole), Zinc, bis(2-benzothiazolethiolato)-, 2-Benzothiazolethiol, zinc salt (2:1), Caswell No. 917, NSC-285168, UNII-HMM5IX9Q3B, 2-Benzothiazolethiol zinc salt, HSDB 5419, Bis(benzothiazole-2-thiolato)zinc, EINECS 205-840-3, EPA Pesticide Chemical Code 051705, EC 205-840-3, SCHEMBL410383, DTXSID6020808, PGNWIWKMXVDXHP-UHFFFAOYSA-L, zinc;1,3-benzothiazole-2-thiolate, Zinc(II) benzo[d]thiazole-2-thiolate, NSC 285168, ZINC MERCAPTOBENZOTHIAZOLE [HSDB], CS-0188512, NS00075634, Z0033, 2(3H)-Benzothiazolethione, zinc salt (2:1), E77122, zinc(2+) bis((1,3-benzothiazol-2-yl)sulfanide), Q27094435, 2(3H)-Benzothiazolethione,zinc salt (2:1), 2(3H)-Benzothiazolethione,zinc salt, Benzothiazole,2-mercapto-,zinc salt, 2-Mercaptobenzothiazole zinc salt, OXAF, Pennac ZT, Tisperse MB 58, Zenite, Zenite Special, Zetax, Zinc mercaptobenzothiazolate, Zinc 2-mercaptobenzothiazole, Zinc mercaptobenzothiazole, ZMBT, Zinc benzothiazolylmercaptide, Zinc 2-benzothiazolethiolate, Mercaptobenzothiazole zinc salt, Bis(2-benzothiazolylthio)zinc, Zinc benzothiazol-2-ylthiolate, Zinc mercaptobenzothiazole salt, Zinc bis(mercaptobenzothiazole), Bis(mercaptobenzothiazolato)zinc, Zinc bis(2-mercaptobenzothiazole), Zinc benzothiazolethiolate, 2-Benzothiazolethiol zinc salt, Hermat Zn-MBT, Vulkacit ZM, Bis(benzothiazole-2-thiolato)zinc, Soxinol MZ, Nocceler MZ, Sanceler MZ, Perkacit ZMBT, MZ, Accelerator MZ, Curekind ZMBT 15, Zinc 2(3H)-benzothiazolethione, 96380-91-5, 12564-44-2, 16529-10-5, 2(3H)-Benzothiazolethione,zinc salt (8CI,9CI), Benzothiazole, 2-mercapto-, zinc salt (6CI), 2-Mercaptobenzothiazole zinc salt, Bis(benzothiazole-2-thiolato)zinc, Hermat Zn-MBT, MZ, Nocceler MZ, OXAF, Pennac ZT, Perkacit ZMBT, Sanceler MZ, Soxinol MZ, ZMBT, Bantex, Zinc Salt of 2-Mercaptobenzothiazole Zetax, 2(3H)-Benzothiazolethione, zinc salt, 2(3H)-Benzothiazolethione, zinc salt (2:1), 2(3H)-Benzothiazolethione, zinc salt, 2-Benzothiazolethiol zinc salt, 2-Benzothiazolethiol, zinc salt (2:1), 2-Mercaptobenzothiazole zinc salt, Bantex, Bis(2-benzothiazolylthio)zinc, Bis(benzothiazole-2-thiolato)zinc, Bis(mercaptobenzothiazolato)zinc, Hermat Zn-MBT, Mercaptobenzothiazole zinc salt, OXAF, Pennac ZT, Tisperse MB-58, Vulkacit ZM, ZMBT, Zenite, Zenite Special, Zetax, Zinc 2-benzothiazolethiolate, Zinc 2-mercaptobenzothiazolate, Zinc 2-mercaptobenzothiazole, Zinc benzothiazol-2-ylthiolate, Zinc benzothiazolethiolate, Zinc benzothiazolyl mercaptide, Zinc benzothiazolylmercaptide, Zinc benzothiazyl-2-mercaptide, Zinc bis(2-mercaptobenzothiazole), Zinc bis(mercaptobenzothiazole), Zinc mercaptobenzothiazolate, Zinc mercaptobenzothiazole salt, Zinc, bis(2-benzothiazolethiolato)-, ZnMB, znmb, ZMBT, oxaf, ZETAX, zenite, bantex, pennaczt, usafgy-7, Zinc MBT, vulkacitzm



Zinc 2-Mercaptobenzothiazole (ZMBT) is a based accelerator.
Zinc 2-Mercaptobenzothiazole (ZMBT) is suitable for NR, BR and SBR as a primary accelerator in combination with ZDMC and ZDEC.
Latex film cured with Zinc 2-Mercaptobenzothiazole (ZMBT) has significantly higher modulus.


The shelf life of Zinc 2-Mercaptobenzothiazole (ZMBT) is 2 years.
Zinc 2-Mercaptobenzothiazole (ZMBT) is a white or light yellow powder with light bitter taste.
Zinc 2-Mercaptobenzothiazole (ZMBT) is hardly soluble in acetone, benzene, ethanol, and carbon tetrachloride.


Zinc 2-Mercaptobenzothiazole (ZMBT) is insoluble in water, gasoline.
Zinc 2-Mercaptobenzothiazole (ZMBT) is decomposed in strong acid and alkali.
Zinc 2-Mercaptobenzothiazole (ZMBT) can be used as an accelerator for natural rubber, synthetic rubber and latex.


Zinc 2-Mercaptobenzothiazole (ZMBT) is similar to that of accelerator M, but its accelerating effect is weak and its vulcanization critical temperature is high (138 °C).
The Zinc 2-Mercaptobenzothiazole (ZMBT) Market has experienced rapid and considerable growth in the recent past, and forecasts suggest that this substantial expansion will persist from 2023 to 2031.


The positive momentum in market dynamics, coupled with the anticipated continued expansion, is indicative of robust growth rates expected throughout the forecasted period.
In essence, the market is poised for significant and noteworthy development.


In recent years, the Zinc 2-Mercaptobenzothiazole(ZMBT) Market has shown a swift and substantial surge, and the projections for continued significant expansion from 2023 to 2031 indicate a persistent upward trend in market dynamics, pointing towards strong growth rates in the foreseeable future.
Due to its special features, Zinc 2-Mercaptobenzothiazole (ZMBT) is a potent chemical substance that is often employed in a variety of sectors.


Zinc 2-Mercaptobenzothiazole (ZMBT) comes from benzothiazole and has a zinc atom, making it extremely useful in a variety of uses.
This outstanding Zinc 2-Mercaptobenzothiazole (ZMBT) is well-known in the rubber sector for its superb accelerating capabilities.
Zinc 2-Mercaptobenzothiazole (ZMBT) improves the vulcanization process when added to rubber formulations, which increases the physical and mechanical qualities of the finished rubber goods.


Additionally, Zinc 2-Mercaptobenzothiazole (ZMBT) has outstanding stability, compatibility, and dispersibility, making it simple to include in a variety of rubber compositions.
Zinc 2-Mercaptobenzothiazole (ZMBT), with the chemical formula C14H8N2S4Zn and CAS registry number 155-04-4, is a compound known for its applications in the rubber industry.


This yellowish powder, also referred to as Zinc 2-Mercaptobenzothiazole (ZMBT), is characterized by its zinc and mercaptobenzothiazole functional groups.
Zinc 2-Mercaptobenzothiazole (ZMBT) is commonly used as an accelerator in the vulcanization process of rubber, providing improved tensile strength and aging resistance.


Additionally, Zinc 2-Mercaptobenzothiazole (ZMBT) exhibits antioxidant properties, protecting rubber materials from degradation caused by heat and oxygen.
Zinc 2-Mercaptobenzothiazole (ZMBT) is an additive which is used in flooring material to allow excellent hardening at low temperatures.
Zinc 2-Mercaptobenzothiazole (ZMBT) is a chemical compound commonly used in the rubber industry.


Zinc 2-Mercaptobenzothiazole (ZMBT) acts as an accelerator in the vulcanization process of rubber, promoting faster curing and improving the mechanical properties of rubber products.
Zinc 2-Mercaptobenzothiazole (ZMBT) can be found in various industries including automotive, aerospace, and construction.
Zinc 2-Mercaptobenzothiazole (ZMBT) should be stored in a cool, well-ventilated area away from incompatible materials.



USES and APPLICATIONS of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
Zinc 2-Mercaptobenzothiazole (ZMBT) is mainly used as the main accelerator together with ZDMC or ZDEC in latex.
Latex films vulcanized with Zinc 2-Mercaptobenzothiazole (ZMBT) have higher modulus.
In addition, good compression deformation resistance can be obtained in foam rubber without increasing the vulcanization time.


Zinc 2-Mercaptobenzothiazole (ZMBT) is mainly used in the manufacture of tires, hoses, rubber shoes, tape and other general industrial products and latex products.
Zinc 2-Mercaptobenzothiazole (ZMBT) is used as rubber accelerator and fungicide.


Zinc 2-Mercaptobenzothiazole (ZMBT) is used for NR, IR, SBR, NBR, EPDM and latex.
Zinc 2-Mercaptobenzothiazole (ZMBT) may be regarded as an intermediate between MBT and MBTS.
Zinc 2-Mercaptobenzothiazole (ZMBT) is used as a secondary accelerator in combination with PZ and EZ.


Similar performance as Zinc 2-Mercaptobenzothiazole (ZMBT) at curing temperature in dry rubber application.
Zinc 2-Mercaptobenzothiazole (ZMBT) has lower scorch and better processing safety.
Zinc 2-Mercaptobenzothiazole (ZMBT) is suitable for mold curing.


Zinc 2-Mercaptobenzothiazole (ZMBT) is easily disperses in rubber; yields non-staining and non-discoloring products.
Zinc 2-Mercaptobenzothiazole (ZMBT) is mainly used in the manufacture of latex products, foam rubber, latex coating gloves, etc.
Zinc 2-Mercaptobenzothiazole (ZMBT) is a semi-ultrafast accelerator widely used in NR/SBR latex compounds along.


Zinc 2-Mercaptobenzothiazole (ZMBT) improves the state of cure in NR based compounds even at 120oC and also improves aging properties.
Zinc 2-Mercaptobenzothiazole (ZMBT) can be dispersed easily in water using common dispersing
agents.


Zinc 2-Mercaptobenzothiazole (ZMBT) can also be used in dry rubber compounds as semi ultra accelerator.
Zinc 2-Mercaptobenzothiazole (ZMBT) is used for NR, IR, SBR, NBR, EPDM and latex.
Zinc 2-Mercaptobenzothiazole (ZMBT) may be regarded as an intermediate between URCC M and URCC DM.


Zinc 2-Mercaptobenzothiazole (ZMBT) is used as a secondary accelerator in combination with URCC PZ and URCC EZ.
Zinc 2-Mercaptobenzothiazole (ZMBT) is mainly used for in the manufacture of latex products, foam rubber, latex coating gloves, etc.
Zinc 2-Mercaptobenzothiazole (ZMBT) is used accelerator for latex, powder coating, fungicide.


Zinc 2-Mercaptobenzothiazole (ZMBT) is a very fast primary or secondary (ultra) accelerator for natural and synthetic rubber.
Zinc 2-Mercaptobenzothiazole (ZMBT) is also a very rapid accelerator for NR and SBR lattices.
Additionally Zinc 2-Mercaptobenzothiazole (ZMBT) is used as an antioxidant in adhesive systems.


Zinc 2-Mercaptobenzothiazole (ZMBT) is mainly used in NR / Synthetic Rubber Latex compounds for the manufacture of Latex Thread, Latex Foam and other Latex based products.
Zinc 2-Mercaptobenzothiazole (ZMBT) in combination with basic secondary accelerators is used in Dry Rubber compounds for the manufacture of Footwear products, Hot air cured products, molded and extruded goods etc.


Zinc 2-Mercaptobenzothiazole (ZMBT) is a Semi ultra-fast accelerator for NR, SBR, NBR, BR and other diene rubbers.
The critical cure temperature of Zinc 2-Mercaptobenzothiazole (ZMBT) is approx. 120° C and hence the dry rubber / NR latex based compounds are vulcanized quickly at 125° C.


Zinc 2-Mercaptobenzothiazole (ZMBT) does not influence the stability of latex compounds.
Zinc 2-Mercaptobenzothiazole (ZMBT) readily disperses in water in the presence of commonly used dispersing agents (e. G. Sodium salt of polymerized alkyl naphthalene sulfonic acid) and is usually used as a 50% dispersion in water for latex compounding applications.


Zinc 2-Mercaptobenzothiazole (ZMBT)has a sensitizing effect on NR Latex due to its thixotropic nature and this property favors NR latex foaming for the production of Latex Foam Products.
The latex compounds in which this property is not desired; The thixotropic effect can be overcome by stirring.


-Normal dosages of Zinc Oxide and Stearic Acid are necessary when Zinc 2-Mercaptobenzothiazole (ZMBT) is used for dry rubber compounding. However; Dosage of Zinc Oxide can be reduced considerably for certain specific applications.
Zinc 2-Mercaptobenzothiazole (ZMBT) can be activated by small dosages of basic accelerators such as TMTM, DPG, TMTD, ZDEC etc. Or even by other basic compounding materials.
If required; Common acidic retarders or Pilgard PVI can be used to delay the on-set of cure.


-High Accelerator-Low Sulfur cure systems based on Zinc 2-Mercaptobenzothiazole (ZMBT) offer excellent heat resistance to NR vulcanizates.
Zinc 2-Mercaptobenzothiazole (ZMBT) also acts as an effective retarder for Sulfur cure systems based on Thiurams & Dithiocarbamates as primary accelerators.



STORAGE AND SHELF LIFE OF ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
Zinc 2-Mercaptobenzothiazole (ZMBT) should be stored in dry, cool, ventilated room; Keep away from water, moisture, high temperature and fire.
Zinc 2-Mercaptobenzothiazole (ZMBT) has a shelf life of at least 12 months if stored in tightly closed original container at room temperature.



PHYSICAL and CHEMICAL PROPERTIES of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
Molecular Weight: 397.9 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 395.886175 g/mol
Monoisotopic Mass: 395.886175 g/mol
Topological Polar Surface Area: 84.3 Ų
Heavy Atom Count: 21
Formal Charge: 0
Complexity: 129
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Melting point: 330 °C
Density: 1.7 g/cm3 (Temp: 25 °C)
Storage temp: Refrigerator
Solubility: Acidic Methanol (Slightly, Heated)
Form: Solid
pKa: 7.03 (at 20 ℃)
Color: White to Off-White
Water Solubility: 20.6 mg/L at 20℃
LogP: 2.42 at 20℃
Indirect Additives used in Food Contact Substances: ZINC 2-MERCAPTOBENZOTHIAZOLE

FDA 21 CFR: 177.2600; 178.3120
CAS DataBase Reference: 155-04-4
FDA UNII: HMM5IX9Q3B
EPA Substance Registry System: Zinc 2-mercaptobenzothiazolate (155-04-4)
Appearance: Light yellow powder
Zn Content: 15-18%
Particle Size: 0.10% (Residue on 150# sieve)
Oil: 1.0-2.0%
Solubility in water: 0.05% max (Zinc)
Melting Range ('C): >200.0
Loss on Drying: 0.3% max
Content: 10% max (Free MBT)

Molecular Weight: 397.85
Molecular Weight: 397.88 g/mol
Exact Mass: 395.886169 g/mol
EC Number: 205-840-3
UNII: HMM5IX9Q3B
DSSTox ID: DTXSID6020808
Color/Form: Light yellow powder
HScode: 2934999090
PSA (Polar Surface Area): 132.86000 Ų
XLogP3: 5.70290
Appearance: Dry powder; Liquid
Density: 1.7 g/cm³ at Temp: 25 °C
Melting Point: 330 °C
Boiling Point: 281.3°C at 760 mmHg



FIRST AID MEASURES of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of ZINC 2-MERCAPTOBENZOTHIAZOLE (ZMBT):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


ZINC ACETATE
ZINC ACETATE What is the most important information I should know about zinc acetate? Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc acetate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc acetate. What is zinc acetate? Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues. Zinc acetate is used to treat and to prevent zinc deficiency. Zinc acetate may also be used for other purposes not listed in this medication guide. What should I discuss with my healthcare provider before taking zinc acetate? Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. It is not known whether zinc acetate will harm an unborn baby. Do not take zinc acetate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc acetate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take zinc acetate? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Take zinc acetate with a full glass of water. Take zinc acetate with food if it upsets your stomach. Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc acetate. The recommended dietary allowance of zinc acetate increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information. Overdose symptoms may include nausea, severe vomiting, dehydration, and restlessness. What should I avoid while taking zinc acetate? Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. What are the possible side effects of zinc acetate? What other drugs will affect zinc acetate? The following drugs can interact with or be made less effective by zinc acetate. Tell your doctor if you are using any of these: This list is not complete and other drugs may interact with zinc acetate. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Where can I get more information? Your pharmacist can provide more information about zinc acetate. Zinc acetate USP is used as/ an astringent in low concentrations and an irritant at high concentrations. It also has mild antibacterial actions similar to those of zinc sulfate. When applied to cuts, it exerts styptic action. Zinc acetate is a salt with the formula Zn(CH3CO2)2, which commonly occurs as the dihydrate Zn(CH3CO2)2·2H2O. Both the hydrate and the anhydrous forms are colorless solids that are commonly used in chemical synthesis and as dietary supplements. Zinc acetates are prepared by the action of acetic acid on zinc carbonate or zinc metal. When used as a food additive, it has the E number E650. Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues. Zinc acetate is used to treat and to prevent zinc deficiency. Zinc acetate may also be used for other purposes not listed in this medication guide.Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc acetate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc acetate. Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. It is not known whether zinc acetate will harm an unborn baby. Do not take zinc acetate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc acetate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Take zinc acetate with a full glass of water. Take zinc acetate with food if it upsets your stomach. Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc acetate. The recommended dietary allowance of zinc acetate increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information. Store at room temperature away from moisture and heat. Zinc can be used for the treatment and prevention of zinc deficiency/its consequences, including stunted growth and acute diarrhea in children, and slowed wound healing. It is also utilized for boosting the immune system, treating the common cold and recurrent ear infections, as well as preventing lower respiratory tract infections 25.Zinc Acetate is a moderately water soluble crystalline Zinc source that decomposes to Zinc oxide on heating. It is generally immediately available in in most volumes, including bulk quantities. All metallic acetates are inorganic salts containing a metal cation and the acetate anion, a univalent (-1 charge) polyatomic ion composed of two carbon atoms ionically bound to three hydrogen and two oxygen atoms (Symbol: CH3COO) for a total formula weight of 59.05. Acetates are excellent precursors for production of ultra high purity compounds, catalysts, and nanoscale materials. We also produce Zinc Acetate Solution. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia)and follows applicable ASTM testing standards. Typical and custom packaging is available, as is additional research, technical and safety (MSDS) data. Please contact us for information on lead time and pricing above. In anhydrous zinc acetate the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures.[5][6][7] In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.[8][9] Heating Zn(CH3CO2)2 in a vacuum results in a loss of acetic anhydride, leaving a residue of basic zinc acetate, with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be4O(OAc)6. Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (<1 Bacteria (CFU/ml)), pyrogen free (<0.03 Endotoxin (EU/ml)), RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/µL) Zinc Acetate Dihydrate is a moderately water soluble crystalline Zinc source that decomposes to Zinc oxide on heating. It is generally immediately available in in most volumes, including bulk quantities. All metallic acetates are inorganic salts containing a metal cation and the acetate anion, a univalent (-1 charge) polyatomic ion composed of two carbon atoms ionically bound to three hydrogen and two oxygen atoms (Symbol: CH3COO) for a total formula weight of 59.05. Acetates are excellent precursors for production of ultra high purity compounds, catalysts, and nanoscale materials. We also produce Zinc Acetate Solution. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia)and follows applicable ASTM testing standards. Typical and custom packaging is available, as is additional research, technical and safety (MSDS) data. Please contact us for information on lead time and pricing above. Chemical name: Zinc acetate dihydrate; CAS Reg. No. 5970-45-6. Storage: Zinc acetate should be kept in a well-closed, non-metallic container. Labelling: The designation on the container should state that the substance is in the dihydrate form and indicate the quantity in terms of the equivalent amount of elemental zinc. Uses Dietary and medicinal applications Zinc acetate has been used in lozenges for treating the common cold.[1] Zinc acetate can also be used to treat zinc deficiencies.[2] As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for Wilson's disease.[3] Zinc acetate is also sold as an astringent in the form of an ointment, a topical lotion, or combined with an antibiotic such as erythromycin for the topical treatment of acne.[4] It is commonly sold as a topical anti-itch ointment. Zinc acetate Generic Name: zinc acetate (ZINK AS e tate) What is zinc acetate? Zinc is a naturally occurring mineral. Zinc is important for growth and for the development and health of body tissues. Zinc acetate is used to treat and to prevent zinc deficiency. Zinc acetate may also be used for other purposes not listed in this medication guide. Important Information Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc acetate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc acetate. Before taking this medicine Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. It is not known whether zinc acetate will harm an unborn baby. Do not take zinc acetate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc acetate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take zinc acetate? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Take zinc acetate with a full glass of water. Take zinc acetate with food if it upsets your stomach. Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc acetate. The recommended dietary allowance of zinc acetate increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information. What should I avoid while taking zinc acetate? Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc acetate side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Less serious side effects may include: nausea; or upset stomach. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Zinc acetate side effects (in more detail) Zinc acetate dosing information -When patient is clinically stable, treatment with zinc acetate can begin; continue chelation therapy as clinically indicated. Health 1-5% solutions are used in the treatment of skin mucosa diseases. In addition, zinc deficiency zinc acetate is used orally at 50-150 mg / day in the developmental stage in children. farming Containing approximately 30% zinc in its structure, it can be used by adding to the feed in salt form to meet the zinc requirement of animals. Porcelain It is used to make glaze on porcelain. Basic properties and structures In anhydrous zinc acetate the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures.[5][6][7] In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.[8][9] Basic zinc acetate Heating Zn(CH3CO2)2 in a vacuum results in a loss of acetic anhydride, leaving a residue of basic zinc acetate, with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be4O(OAc)6.[10] Zinc acetate is an acetate salt in which the cationic component is zinc(2+). It has a role as an astringent. It is a zinc molecular entity and an acetate salt. Zinc acetate has been used as an excipient in a variety of pharmaceutical formulations including topical gels, lotions, and solutions, and subcutaneous injections. It has also been investigated for use in an oral controlled-release formulation for water-soluble drugs in combination with sodium alginate and xanthan gum. Therapeutically, zinc acetate has been used in oral capsules for the treatment of Wilson's disease. Zinc acetate has also been demonstrated to be effective as a spermicide in vaginal contraceptives. Zinc Acetate Dihydrate is a moderately water soluble crystalline Zinc source that decomposes to Zinc oxide on heating. Acetates are excellent precursors for production of ultra high purity compounds, catalysts, and nanoscale materials. Formula Zn(C2H3O2).2H2O, 1.735 g/mL, e.n. 200 °C decay point 200, losing two mol water in 100 °C, dissolved in water and alcohol, drugs, wood protection, textile dyeing, zinc chromate synthesis, laboratories, ceramic glazing, seed additiveused in the solid substance. A discontinued use of dilute zinc acetate solutions is as an emetic. Zinc acetate is used to treat and to prevent zinc deficiency. Zinc acetate may also be used for other purposes not listed in this medication guide. Zinc acetate anhydrous is used in the synthesis of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis. It is utilized in the ultrasonic preparation of zinc sulfide nanoparticles coated on silica particles. It is administered orally or parenterally as a nutritional supplement. It finds an application in the field of industries such as wood preservation, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. It also acts as a plating inhibitor on primary water piping. Zinc acetate may also be used for other purposes not listed in this medication guide. Important Information Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc acetate can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking zinc acetate. Before taking this medicine Before using zinc acetate, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use zinc acetate if you have certain medical conditions. It is not known whether zinc acetate will harm an unborn baby. Do not take zinc acetate without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zinc acetate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take zinc acetate? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Take zinc acetate with a full glass of water. Take zinc acetate with food if it upsets your stomach. Your healthcare provider may occasionally change your dose to make sure you get the best results from zinc acetate. The recommended dietary allowance of zinc acetate increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information. What should I avoid while taking zinc acetate? Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb zinc acetate. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc acetate side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Less serious side effects may include: nausea; or upset stomach. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. See also: Zinc acetate side effects (in more detail) Zinc acetate dosing information -When patient is clinically stable, treatment with zinc acetate can begin; continue chelation therapy as clinically indicated. Health 1-5% solutions are used in the treatment of skin mucosa diseases. In addition, zinc deficiency zinc acetate is used orally at 50-150 mg / day in the developmental stage in children. farming Containing approximately 30% zinc in its structure, it can be used by adding to the feed in salt form to meet the zinc requirement of animals. Porcelain It is used to make glaze on porcelain. Basic properties and structures In anhydrous zinc acetate the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures.[5][6][7] In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In zinc acetate dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.[8][9] Basic zinc acetate Heating Zn(CH3CO2)2 in a vacuum results in a loss of acetic anhydride, leaving a residue of basic zinc acetate, with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be4O(OAc)6.[10] Zinc acetate is an acetate salt in which the cationic component is zinc(2+). It has a role as an astringent. It is a zinc molecular entity and an acetate salt. Zinc acetate has been used as an excipient in a variety of pharmaceutical formulations including topical gels, lotions, and solutions, and subcutaneous injections. It has also been investigated for use in an oral controlled-release formulation for water-soluble drugs in combination with sodium alginate and xanthan gum. Therapeutically, zinc acetate has been used in oral capsules for the treatment of Wilson's disease. Zinc acetate has also been demonstrated to be effective as a spermicide in vaginal contraceptives. Zinc Acetate Dihydrate is a moderately water soluble crystalline Zinc source that decomposes to Zinc oxide on heating. Acetates are excellent precursors for production of ultra high purity compounds, catalysts, and nanoscale materials. Formula Zn(C2H3O2).2H2O, 1.735 g/mL, e.n. 200 °C decay point 200, losing two mol water in 100 °C, dissolved in water and alcohol, drugs, wood protection, textile dyeing, zinc chromate synthesis, laboratories, ceramic glazing, seed additiveused in the solid substance. A discontinued use of dilute zinc acetate solutions is as an emetic. Zinc acetate is used to treat and to prevent zinc deficiency. Zinc acetate may also be used for other purposes not listed in this medication guide. Zinc acetate anhydrous is used in the synthesis of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis. It is utilized in the ultrasonic preparation of zinc sulfide nanoparticles coated on silica particles. It is administered orally or parenterally as a nutritional supplement. It finds an application in the field of industries such as wood preservation, manufacturing other zinc salts, polymers, manufacture of ethylene acetate, as a dye mordant, and analytical reagent. It also acts as a plating inhibitor on primary water piping.
ZINC ACETATE ANHYDROUS
ZINC ASPARTATE N° CAS : 36393-20-1 Nom INCI : ZINC ASPARTATE Nom chimique : Dihydrogen bis[L-aspartato(2-)-N,O1]zincate(2-) N° EINECS/ELINCS : 253-012-5 Classification : Règlementé Restriction en Europe : III/24 Ses fonctions (INCI) Agent d'entretien de la peau : Maintient la peau en bon état Produits qui en contiennent
ZINC ACETATE DIHYDRATE

Zinc acetate dihydrate is a chemical compound with the molecular formula Zn(CH₃COO)₂·2H₂O.
Zinc acetate dihydrate is the hydrated form of zinc acetate, meaning it contains two molecules of water (di = 2, hydrate = water) in addition to the zinc acetate molecules.
The chemical formula indicates that the compound consists of zinc ions (Zn²⁺) coordinated with acetate ions (CH₃COO⁻) and water molecules.

CAS Number: 5970-45-6
EC Number: 205-743-6
Chemical Formula: Zn(CH₃COO)₂·2H₂O
Common Name: Zinc acetate dihydrate
Molecular Weight: Approximately 219.50 g/mol (for the dihydrate form)
Appearance: It is a white crystalline solid.

Zinc Diacetate Dihydrate, Zinc Ethanoate Dihydrate, Zinc Salt of Acetic Acid Dihydrate, Dihydrated Zinc Acetate, Zinc Bis(acetate) Dihydrate, Zincous Acetate Dihydrate, Zinc(II) Acetate Dihydrate, Zinc(2+) Acetate Dihydrate, Zinc Diethanoate Dihydrate, Dihydroxydioxidozinc Dihydrate, Zinc(2+) Ethanoate Dihydrate, Dizinc Acetate Dihydrate, Zinc Acetic Acid Dihydrate, Dihydrate Zinc Acetate, Zinc Di(acetic acid) Dihydrate, Zinc Di(acetate) Dihydrate, Zinc Acetate 2H2O, Zinc Diethanoate Dihydrate, Zinc(II) Ethanoate Dihydrate, Zinc Di(acetate) 2H2O, Zinc Diacetate Dihydrate, Dihydrated Zinc Acetate, Zincous Acetate Dihydrate, Dihydroxydioxidozinc Dihydrate, Zinc Diethanoate Dihydrate, Zinc Diacetate 2H2O, Zinc Di(acetic acid) Dihydrate, Zinc Di(acetate) 2H2O, Zinc Acetate 2H2O, Zinc Ethanoate Dihydrate, Dizinc Acetate Dihydrate, Dihydrate Zinc Acetate, Zinc Di(acetic acid) Dihydrate, Zinc Di(acetate) Dihydrate, Zinc Acetate 2H2O, Zinc Diethanoate Dihydrate, Zinc(II) Ethanoate Dihydrate, Zinc Di(acetate) 2H2O, Zinc Diacetate Dihydrate, Dihydrated Zinc Acetate, Zincous Acetate Dihydrate, Dihydroxydioxidozinc Dihydrate, Zinc Diethanoate Dihydrate, Zinc Diacetate 2H2O, Zinc Di(acetic acid) Dihydrate, Zinc Di(acetate) 2H2O, Zinc Acetate 2H2O, Zinc Ethanoate Dihydrate, Dizinc Acetate Dihydrate, Dihydrate Zinc Acetate, Zinc Di(acetic acid) Dihydrate, Zinc Di(acetate) Dihydrate, Zinc Acetate 2H2O, Zinc Diethanoate Dihydrate, Zinc(II) Ethanoate Dihydrate, Zinc Di(acetate) 2H2O



APPLICATIONS


Zinc acetate dihydrate finds application as a dietary supplement, providing a bioavailable source of zinc.
In the pharmaceutical industry, it may be used in the formulation of certain medications.
Zinc acetate dihydrate serves as a precursor in the synthesis of other zinc-containing compounds.

Zinc acetate dihydrate is utilized in the preparation of zinc oxide for various industrial applications.
Zinc acetate dihydrate plays a role in the production of antifungal creams and ointments.
In the textile industry, the compound is employed as a mordant in dyeing processes.
The pharmaceutical sector utilizes Zinc Acetate Dihydrate in the preparation of oral care products.

Zinc acetate dihydrate has applications in the creation of zinc-based catalysts for chemical reactions.
Zinc acetate dihydrate is used in the production of certain skincare and cosmetic formulations.
In the food industry, Zinc Acetate Dihydrate may be employed as a nutrient supplement.

Zinc acetate dihydrate finds use in the synthesis of zinc-containing nanoparticles for various applications.
Zinc acetate dihydrate is applied in the creation of corrosion-resistant coatings for metals.
Zinc acetate dihydrate serves as a reagent in certain laboratory experiments and research studies.

In the field of ceramics, it may be used in the preparation of certain glazes.
Zinc acetate dihydrate is utilized in the textile and leather industries for specific treatments.

Zinc acetate dihydrate has potential applications in wood preservation treatments.
Zinc acetate dihydrate is involved in the creation of certain pigments used in artistic paints.
The pharmaceutical sector may use it in the development of zinc-based medications.

Zinc acetate dihydrate is employed in the synthesis of coordination polymers and metal-organic frameworks (MOFs).
Zinc acetate dihydrate has applications in the creation of zinc-containing glass for various purposes.
Zinc acetate dihydrate is explored for its potential antimicrobial properties.
In the field of catalysis, it participates in reactions involving zinc ions.

Zinc acetate dihydrate is studied for its role in the development of sustainable technologies.
Zinc acetate dihydrate solutions are used in the creation of chemical sensors for specific analytes.
Zinc acetate dihydrate has potential applications in the treatment of timber to protect against decay and degradation.

Zinc acetate dihydrate is utilized in the preparation of zinc-containing dietary supplements due to its bioavailability.
In the petrochemical industry, it may serve as a catalyst in certain chemical processes.
Zinc acetate dihydrate finds application in the creation of zinc-based fertilizers for agricultural use.
Zinc acetate dihydrate is explored for its potential use in the development of zinc-based antiviral agents.

In the rubber industry, Zinc Acetate Dihydrate is used as an activator in the vulcanization process.
Zinc acetate dihydrate plays a role in the production of zinc stearate, a commonly used lubricant in the plastics industry.

Zinc acetate dihydrate may be involved in the creation of zinc-containing coatings for corrosion protection.
In the manufacturing of ceramics, Zinc Acetate Dihydrate is employed for specific glaze formulations.
Zinc acetate dihydrate is used in the preparation of zinc-containing materials for the synthesis of nanocomposites.
The pharmaceutical sector explores its potential in the development of zinc-based drugs for medicinal purposes.

Zinc acetate dihydrate is applied in the creation of zinc-containing pigments for paints and inks.
Zinc acetate dihydrate is studied for its role in the synthesis of zinc oxide nanoparticles for various applications.
In the textile industry, it may be used in dyeing processes as a mordant to enhance colorfastness.

Zinc acetate dihydrate finds use in the creation of zinc-containing solutions for wood preservation.
Zinc acetate dihydrate is employed in the preparation of zinc-containing electrolytes for batteries.

Zinc acetate dihydrate plays a part in the development of zinc-based catalysts for organic transformations.
Zinc acetate dihydrate may be used in the creation of zinc-containing coatings for corrosion resistance in marine environments.
In the creation of certain flame-retardant materials, Zinc Acetate Dihydrate is utilized.

Zinc acetate dihydrate is studied for its potential use in the creation of zinc-containing materials for biomedical applications.
The pharmaceutical sector explores its role in zinc supplementation for various health-related applications.
Zinc acetate dihydrate may be employed in the synthesis of zinc-containing nanoparticles for drug delivery.
Zinc acetate dihydrate finds application in the preparation of zinc-containing materials for gas sensing applications.

In the creation of certain adhesives and sealants, the compound may be included for enhanced properties.
Zinc acetate dihydrate is studied for its potential use in the development of zinc-based contrast agents for medical imaging.
Zinc acetate dihydrate is explored for its role in the creation of zinc-containing materials for use in electronic devices.

Zinc acetate dihydrate is employed in the formulation of zinc-containing supplements for animal nutrition.
In the field of wastewater treatment, it may find applications in certain precipitation processes.

Zinc acetate dihydrate is utilized in the preparation of zinc-containing solutions for electroplating applications.
Zinc acetate dihydrate plays a role in the creation of zinc-based materials for use in photovoltaic devices.
Zinc acetate dihydrate is explored for its potential use in the synthesis of zinc-containing nanomaterials.

In the construction industry, it may be used in the creation of corrosion-resistant coatings for steel structures.
Zinc acetate dihydrate is studied for its role in the development of zinc-based materials for water purification.

Zinc acetate dihydrate finds application in the creation of zinc-containing solutions for soil remediation.
Zinc acetate dihydrate is utilized in the formulation of zinc-based antiperspirants and deodorants.
In the field of catalysis, it may be involved in reactions for the conversion of renewable resources.

Zinc acetate dihydrate plays a part in the preparation of zinc-containing materials for use in sensors and detectors.
The pharmaceutical sector explores its potential in the development of zinc-based therapies for skin conditions.
Zinc acetate dihydrate may be used in the preparation of zinc-containing materials for gas separation.

Zinc acetate dihydrate is applied in the creation of zinc-containing coatings for medical devices to prevent corrosion.
Zinc acetate dihydrate finds use in the creation of zinc-based materials for flame-retardant applications.
In the field of energy storage, it may be explored for use in zinc-ion batteries.
Zinc acetate dihydrate is studied for its role in the creation of zinc-containing materials for tissue engineering.

Zinc acetate dihydrate finds application in the preparation of zinc-containing solutions for the regeneration of ion exchange resins.
Zinc acetate dihydrate is employed in the synthesis of zinc oxide nanoparticles for antimicrobial coatings.
Zinc acetate dihydrate is explored for its potential use in the development of zinc-based materials for 3D printing.

Zinc acetate dihydrate may be used in the creation of zinc-containing materials for photocatalytic applications.
In the field of analytical chemistry, it may serve as a reagent in certain qualitative tests for zinc ions.

The pharmaceutical sector explores its potential use in the formulation of zinc-based topical creams.
Zinc acetate dihydrate is applied in the preparation of zinc-containing materials for humidity sensors.
Zinc acetate dihydrate may be involved in the creation of zinc-based materials for use in water desalination processes.

Zinc acetate dihydrate is used in the preparation of zinc-containing materials for corrosion-resistant coatings on automotive parts.
In the manufacturing of paints and varnishes, it may be employed as a drying agent for certain formulations.
Zinc acetate dihydrate finds application in the production of zinc-containing adhesives for various bonding applications.

Zinc acetate dihydrate is explored for its potential use in the creation of zinc-based materials for flexible electronics.
Zinc acetate dihydrate plays a role in the synthesis of zinc-containing materials for use in the production of anti-reflective coatings.
In the electronics industry, it may be used in certain processes for the fabrication of semiconductors.

Zinc acetate dihydrate is employed in the creation of zinc-containing materials for use in printed circuit boards.
Zinc acetate dihydrate finds application in the preparation of zinc-based solutions for electroless plating.
Zinc acetate dihydrate is studied for its role in the development of zinc-containing materials for biomedical implants.

In the creation of specialty glass, it may be used in the preparation of zinc-containing glass compositions.
Zinc acetate dihydrate finds use in the formulation of zinc-containing materials for use in the production of photonic devices.
Zinc acetate dihydrate is explored for its potential use in the creation of zinc-based materials for solar cell applications.

Zinc acetate dihydrate plays a part in the synthesis of zinc-containing materials for use in transparent conductive coatings.
In the field of ceramic glazes, it may be applied for the creation of unique textures and finishes.

The pharmaceutical sector explores its potential in the formulation of zinc-based treatments for gastrointestinal disorders.
Zinc acetate dihydrate is utilized in the creation of zinc-containing materials for use in electrochemical sensors.
Zinc acetate dihydrate may be involved in the preparation of zinc-based materials for anti-corrosion coatings on marine structures.

Zinc acetate dihydrate is explored for its potential use in the creation of zinc-containing materials for 3D printing of implants.
In the creation of zinc-containing materials for use in photonic crystals, it plays a significant role.

Zinc acetate dihydrate is applied in the preparation of zinc-based materials for use in gas sensing devices.
Zinc acetate dihydrate finds application in the formulation of zinc-containing materials for protective coatings on glass surfaces.
The pharmaceutical sector explores its potential use in the formulation of zinc-based treatments for viral infections.

Zinc acetate dihydrate may be used in the creation of zinc-containing materials for use in flexible and transparent conductive films.
Zinc acetate dihydrate is studied for its role in the development of zinc-containing materials for targeted drug delivery systems.
In the production of zinc-containing catalysts, Zinc Acetate Dihydrate is employed for specific catalytic transformations.



DESCRIPTION


Zinc acetate dihydrate is a chemical compound with the molecular formula Zn(CH₃COO)₂·2H₂O.
Zinc acetate dihydrate is the hydrated form of zinc acetate, meaning it contains two molecules of water (di = 2, hydrate = water) in addition to the zinc acetate molecules.
The chemical formula indicates that the compound consists of zinc ions (Zn²⁺) coordinated with acetate ions (CH₃COO⁻) and water molecules.

Zinc acetate dihydrate is a crystalline white solid.
Zinc acetate dihydrate has the chemical formula Zn(CH₃COO)₂·2H₂O.
Zinc acetate dihydrate is a hydrated form of zinc acetate, containing two water molecules.

The appearance of Zinc Acetate Dihydrate is characterized by its distinctive crystalline structure.
In its solid state, it exhibits a fine, powdery texture.
Zinc acetate dihydrate is soluble in water, forming a clear solution.

Zinc acetate dihydrate has a role in various industrial and chemical processes.
Zinc acetate dihydrate is commonly used in the preparation of zinc-containing materials.
The hydrated form suggests a water content that contributes to its physical properties.

Zinc acetate dihydrate is a source of zinc ions in certain applications.
Zinc acetate dihydrate plays a part in chemical reactions involving acetate ions.

Zinc acetate dihydrate is known for its role as a precursor in the synthesis of other zinc compounds.
Zinc acetate dihydrate is employed in laboratory settings for experimental purposes.

Zinc acetate dihydrate may have applications in the pharmaceutical industry.
Its white color makes it visually distinctive in various formulations.
The dihydrate form suggests susceptibility to hydration and dehydration processes.

Zinc acetate dihydrate may be used in dietary supplements as a source of zinc.
The two water molecules in its structure contribute to its molar mass.
Zinc Acetate Dihydrate is sensitive to environmental conditions such as humidity.

It may be involved in reactions where zinc ions play a catalytic role.
The chemical structure indicates the presence of zinc in its +2 oxidation state.

The dihydrate form implies a specific stoichiometry in its composition.
This compound is handled with care due to its potential health and safety considerations.

Zinc Acetate Dihydrate is utilized in chemical research and academic studies.
Its physical and chemical properties make it versatile for a range of applications in various industries.



PROPERTIES


Physical Properties:

Color: White (crystalline solid).
Form: Fine powder or crystalline structure.
Odor: Odorless.
Solubility: Soluble in water.
Molecular Weight: Approximately 219.50 g/mol (for the dihydrate form).
Melting Point: Decomposes before melting.


Chemical Properties:

Chemical Formula: Zn(CH₃COO)₂·2H₂O.
Zinc Oxidation State: +2.
Acetate Ion: CH₃COO⁻.


Hydration State:

Hydration: Dihydrate form, indicating the presence of two water molecules.


Crystal Structure:

Crystal System: Varies depending on the crystalline form.
Crystal Habit: Crystallizes in a specific structure.


Stability:

Stable Under Normal Conditions: Generally stable, but may be sensitive to environmental conditions.



FIRST AID


Inhalation:

Move to Fresh Air:
If inhalation of zinc acetate dihydrate dust or vapors occurs, promptly move the affected person to an area with fresh air.
Ensure that the person is breathing comfortably.

Seek Medical Attention:
If respiratory difficulties persist or if there are signs of respiratory distress, seek immediate medical attention.
Provide information about the type and duration of exposure.


Skin Contact:

Remove Contaminated Clothing:
In case of skin contact, promptly remove contaminated clothing.
Rinse the affected skin area with plenty of water and mild soap for at least 15 minutes.

Wash Skin:
Wash the skin thoroughly to remove any remaining zinc acetate dihydrate.
Avoid using abrasive materials that may further irritate the skin.

Seek Medical Attention:
If irritation, redness, or other adverse skin reactions occur, seek medical advice.
Provide information about the extent and duration of exposure.


Eye Contact:

Flush Eyes:
In case of eye contact, immediately flush the eyes with gentle, flowing water for at least 15 minutes.
Ensure eyelids are held open during flushing.

Seek Medical Attention:
If irritation persists or if there are signs of eye injury, seek immediate medical attention.
Provide information about the type and duration of exposure.


Ingestion:

Do Not Induce Vomiting:
If zinc acetate dihydrate is ingested, do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water if the person is conscious and able to swallow.

Seek Medical Attention:
Seek immediate medical attention and provide the medical personnel with details about the ingested substance.


General First Aid Precautions:

Provide Comfort:
Keep the affected person calm and provide reassurance during first aid measures.
If the person is in shock, provide comfort and keep them warm.

Protective Equipment:
If administering first aid, wear appropriate personal protective equipment, such as gloves and safety glasses.
Avoid direct contact with the substance.

Do Not Delay Medical Attention:
If there is any uncertainty about the severity of exposure or if symptoms persist, seek prompt medical attention.
Follow any specific first aid instructions provided by medical personnel.



HANDLING AND STORAGE


Handling Conditions:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including gloves, safety glasses or goggles, and a lab coat or protective clothing.
Consider the use of respiratory protection if handling in dusty environments.

Ventilation:
Use in a well-ventilated area or under local exhaust ventilation to minimize exposure to dust or vapors, especially in industrial settings.

Avoid Contamination:
Prevent contamination of zinc acetate dihydrate by ensuring that equipment, containers, and tools are clean and free of foreign substances.
Use dedicated equipment for handling zinc acetate dihydrate.

Temperature Considerations:
Be aware of temperature sensitivity, especially for anhydrous forms.
Follow recommended temperature ranges for handling.

Handling Procedures:
Follow safe handling procedures, including proper lifting techniques and the use of equipment to avoid spillage.
Minimize dust generation during handling.

Avoiding Skin Contact:
Minimize skin contact with zinc acetate dihydrate.
If contact occurs, wash the affected area thoroughly with water and mild soap.
Use barrier creams or protective clothing to prevent skin exposure.

Use in accordance with Regulations:
Adhere to local regulations and guidelines for the safe handling and use of zinc acetate dihydrate.
Obtain and review the safety data sheet (SDS) for specific handling instructions.


Storage Conditions:

Temperature and Humidity:
Store zinc acetate dihydrate in a cool, dry place, away from direct sunlight and extreme temperatures.
Some forms, especially hydrates, may have specific storage temperature requirements.

Separation from Incompatible Substances:
Store zinc acetate dihydrate away from incompatible substances, including strong acids, bases, and certain metals.
Follow segregation guidelines to prevent chemical reactions.

Container Integrity:
Ensure that storage containers, such as bottles or drums, are in good condition, properly sealed, and labeled with relevant information, including product identity and hazards.

Avoiding Contamination:
Store zinc acetate dihydrate away from materials that may contaminate it.
Use dedicated storage areas for chemicals.
Implement good housekeeping practices to minimize the risk of contamination.

Segregation from Food and Pharmaceuticals:
Keep zinc acetate dihydrate away from areas where food, pharmaceuticals, or other sensitive products are stored.
Store in designated chemical storage areas.

Protection from Moisture:
For anhydrous forms, protect from moisture to prevent clumping and caking.
Consider using moisture-resistant packaging.
For hydrates, store in conditions that prevent excessive moisture absorption.

Proper Handling of Bags and Drums:
Handle bags and drums of zinc acetate dihydrate carefully to avoid damage, spills, or punctures.
Use appropriate lifting equipment and storage racks.

Labeling and Documentation:
Clearly label storage containers with product information, hazard warnings, and handling instructions.
Maintain up-to-date documentation, including the safety data sheet (SDS) and emergency contact information.

Emergency Equipment:
Keep emergency equipment, such as spill response kits, eye wash stations, and emergency showers, accessible in the storage area.
Ensure that personnel are trained on emergency procedures.

Regular Inspections:
Conduct regular inspections of storage areas to ensure compliance with safety and regulatory requirements.
Address any issues promptly, and document corrective actions.
ZINC ACETATE SOLUTION
ZINC ACETATE SOLUTION About Zinc Acetate Solution Acetate Formula StructureZinc Acetate Solutions are moderate to highly concentrated liquid solutions of Zinc Acetate Solution. They are an excellent source of Zinc Acetate Solution for applications requiring solubilized materials. Zinc Acetate Solution Solution Synonyms Zinc Diacetate, Dicarbomethoxyzinc, Galzin, Zinc Cetate Anhydrous, Zinc Acetate Solution Dihydrate, Zinc Acetate Solution [USAN], Zinc Acetate Solution, Zinc(II) Acetate, Siltex CL 4, Zinc Diacetate Dihydrate, Octan Zinecnaty, Zinc di(Acetate), Acetic Acid, Zinc Salt Zinc Acetate Solution the free encyclopedia Jump to navigationJump to search Zinc Acetate Solution Zinc Acetate Solution crystals Names IUPAC name Zinc Acetate Solution Infobox references Zinc Acetate Solution is a salt with the formula Zn(CH3CO2)2, which commonly occurs as the dihydrate Zn(CH3CO2)2·2H2O. Both the hydrate and the anhydrous forms are colorless solids that are commonly used in chemical synthesis and as dietary supplements. Zinc Acetate Solutions are prepared by the action of acetic acid on zinc carbonate or zinc metal. When used as a food additive, it Zinc Acetate Solution has been used in lozenges for treating the common cold.[1] Zinc Acetate Solution can also be used to treat zinc deficiencies.[2] As an oral daily supplement it is used to inhibit the body's absorption of copper as part of the treatment for Wilson's disease.[3] Zinc Acetate Solution is also sold as an astringent in the form of an ointment, a topical lotion, or combined with an antibiotic such as erythromycin for the topical treatment of acne.[4] It is commonly sold as a topical anti-itch ointment. Basic properties and structures In anhydrous Zinc Acetate Solution the zinc is coordinated to four oxygen atoms to give a tetrahedral environment, these tetrahedral polyhedra are then interconnected by acetate ligands to give a range of polymeric structures.[5][6][7] In contrast, most metal diacetates feature metals in octahedral coordination with bidentate acetate groups. In Zinc Acetate Solution dihydrate the zinc is octahedral, wherein both acetate groups are bidentate.[8][9] Basic Zinc Acetate Solution Heating Zn(CH3CO2)2 in a vacuum results in a loss of acetic anhydride, leaving a residue of basic Zinc Acetate Solution, with the formula Zn4O(CH3CO2)6. This cluster compound has the tetrahedral structure shown below. This species closely resembles the corresponding beryllium compound, although it is slightly expanded with Zn-O distances ~1.97 vs ~1.63 Å for Be4O(OAc)6.[10] Zinc lozenges and the common cold: a meta-analysis comparing Zinc Acetate Solution and zinc gluconate, and the role of zinc dosage. To compare the efficacy of Zinc Acetate Solution lozenges with zinc gluconate lozenges in common cold treatment and to examine the dose-dependency of the effect. Meta-analysis. Placebo-controlled zinc lozenge trials, in which the zinc dose was > 75 mg/day. The pooled effect of zinc lozenges on common cold duration was calculated by using inverse-variance random-effects method. Seven randomised trials with 575 participants with naturally acquired common colds. Duration of the common cold. The mean common cold duration was 33% (95% CI 21% to 45%) shorter for the zinc groups of the seven included trials. Three trials that used lozenges composed of Zinc Acetate Solution found that colds were shortened by 40% and four trials that used zinc gluconate by 28%. The difference between the two salts was not significant: 12 percentage points (95% CI: -12 to + 36). Five trials used zinc doses of 80-92 mg/day, common cold duration was reduced by 33%, and two trials used zinc doses of 192-207 mg/day and found an effect of 35%. The difference between the high-dose and low-dose zinc trials was not significant: 2 percentage points (95% CI: -29 to + 32). Properly composed zinc gluconate lozenges may be as effective as Zinc Acetate Solution lozenges. There is no evidence that zinc doses over 100 mg/day might lead to greater efficacy in the treatment of the common cold. Common cold patients may be encouraged to try zinc lozenges for treating their colds. The optimal lozenge composition and dosage scheme need to be investigated further. Digital selective growth of a ZnO nanowire array by large scale laser decomposition of Zinc Acetate Solution. We develop a digital direct writing method for ZnO NW micro-patterned growth on a large scale by selective laser decomposition of Zinc Acetate Solution. For ZnO NW growth, by replacing the bulk heating with the scanning focused laser as a fully digital local heat source, Zinc Acetate Solution crystallites can be selectively activated as a ZnO seed pattern to grow ZnO nanowires locally on a larger area. Together with the selective laser sintering process of metal nanoparticles, more than 10,000 UV sensors have been demonstrated on a 4 cm × 4 cm glass substrate to develop all-solution processible, all-laser mask-less digital fabrication of electronic devices including active layer and metal electrodes without any conventional vacuum deposition, photolithographic process, premade mask, high temperature and vacuum environment. Zinc Acetate Solution lozenges for treating the common cold: an individual patient data meta-analysis. The aim of this study was to determine whether the allergy status and other characteristics of common cold patients modify the effects of Zinc Acetate Solution lozenges. We had available individual patient data for three randomized placebo-controlled trials in which Zinc Acetate Solution lozenges were administered to common cold patients. We used both one stage and two stage meta-analysis to estimate the effects of zinc lozenges. The total number of common cold patients was 199, the majority being females. Eighty percent of them fell into the age range 20-50 years. One third of the patients had allergies. The one stage meta-analysis gave an overall estimate of 2.73 days (95% CI 1.8, 3.3 days) shorter colds by Zinc Acetate Solution lozenge usage. The two stage meta-analysis gave an estimate of 2.94 days (95% CI 2.1, 3.8 days) reduction in common cold duration. These estimates are to be compared with the 7 day average duration of colds in the three trials. The effect of zinc lozenges was not modified by allergy status, smoking, baseline severity of the common cold, age, gender or ethnic group. Since the effects of Zinc Acetate Solution lozenges were consistent between the compared subgroups, the overall estimates for effect seemed applicable over a wide range of common cold patients. While the optimal composition of zinc lozenges and the best frequency of their administration should be further investigated, given the current evidence of efficacy, common cold patients may be encouraged to try zinc lozenges for treating their colds. © 2016 The British Pharmacological Society. Zinc Acetate Solution lozenges for treating the common cold: an individual patient data meta‐analysis Aims The aim of this study was to determine whether the allergy status and other characteristics of common cold patients modify the effects of Zinc Acetate Solution lozenges. Methods We had available individual patient data for three randomized placebo‐controlled trials in which Zinc Acetate Solution lozenges were administered to common cold patients. We used both one stage and two stage meta‐analysis to estimate the effects of zinc lozenges. Results The total number of common cold patients was 199, the majority being females. Eighty percent of them fell into the age range 20–50 years. One third of the patients had allergies. The one stage meta‐analysis gave an overall estimate of 2.73 days (95% CI 1.8, 3.3 days) shorter colds by Zinc Acetate Solution lozenge usage. The two stage meta‐analysis gave an estimate of 2.94 days (95% CI 2.1, 3.8 days) reduction in common cold duration. These estimates are to be compared with the 7 day average duration of colds in the three trials. The effect of zinc lozenges was not modified by allergy status, smoking, baseline severity of the common cold, age, gender or ethnic group. Conclusion Since the effects of Zinc Acetate Solution lozenges were consistent between the compared subgroups, the overall estimates for effect seemed applicable over a wide range of common cold patients. While the optimal composition of zinc lozenges and the best frequency of their administration should be further investigated, given the current evidence of efficacy, common cold patients may be encouraged to try zinc lozenges for treating their colds. PMID:27378206 The effectiveness of high dose Zinc Acetate Solution lozenges on various common cold symptoms: a meta-analysis. A previous meta-analysis found that high dose Zinc Acetate Solution lozenges reduced the duration of common colds by 42%, whereas low zinc doses had no effect. Lozenges are dissolved in the pharyngeal region, thus there might be some difference in the effect of zinc lozenges on the duration of respiratory symptoms in the pharyngeal region compared with the nasal region. The objective of this study was to determine whether Zinc Acetate Solution lozenges have different effects on the duration of common cold symptoms originating from different anatomical regions. We analyzed three randomized trials on Zinc Acetate Solution lozenges for the common cold administering zinc in doses of 80-92 mg/day. All three trials reported the effect of zinc on seven respiratory symptoms, and three systemic symptoms. We pooled the effects of zinc lozenges for each symptom and calculated point estimates and 95% confidence intervals (95% CI). Zinc Acetate Solution lozenges shortened the duration of nasal discharge by 34% (95% CI: 17% to 51%), nasal congestion by 37% (15% to 58%), sneezing by 22% (-1% to 45%), scratchy throat by 33% (8% to 59%), sore throat by 18% (-10% to 46%), hoarseness by 43% (3% to 83%), and cough by 46% (28% to 64%). Zinc lozenges shortened the duration of muscle ache by 54% (18% to 89%), but there was no difference in the duration of headache and fever. The effect of Zinc Acetate Solution lozenges on cold symptoms may be associated with the local availability of zinc from the lozenges, with the levels being highest in the pharyngeal region. However our findings indicate that the effects of zinc ions are not limited to the pharyngeal region. There is no indication that the effect of zinc lozenges on nasal symptoms is less than the effect on the symptoms of the pharyngeal region, which is more exposed to released zinc ions. Given that the adverse effects of zinc in the three trials were minor, Zinc Acetate Solution lozenges releasing zinc ions at doses of about 80 mg/day may be a useful treatment for the common cold Zinc Acetate Solution Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis. A previous meta-analysis of 3 Zinc Acetate Solution lozenge trials estimated that colds were on average 40% shorter for the zinc groups. However, the duration of colds is a time outcome, and survival analysis may be a more informative approach. The objective of this individual patient data (IPD) meta-analysis was to estimate the effect of Zinc Acetate Solution lozenges on the rate of recovery from colds. We analyzed IPD for 3 randomized placebo-controlled trials in which 80-92 mg/day of elemental zinc were administered as Zinc Acetate Solution lozenges to 199 common cold patients. We used mixed-effects Cox regression to estimate the effect of zinc. Patients administered zinc lozenges recovered faster by rate ratio 3.1 (95% confidence interval, 2.1-4.7). The effect was not modified by age, sex, race, allergy, smoking, or baseline common cold severity. On the 5th day, 70% of the zinc patients had recovered compared with 27% of the placebo patients. Accordingly, 2.6 times more patients were cured in the zinc group. The difference also corresponds to the number needed to treat of 2.3 on the 5th day. None of the studies observed serious adverse effects of zinc. The 3-fold increase in the rate of recovery from the common cold is a clinically important effect. The optimal formulation of zinc lozenges and an ideal frequency of their administration should be examined. Given the evidence of efficacy, common cold patients may be instructed to try Zinc Acetate Solution lozenges within 24 hours of onset of symptoms. © The Author 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. Evaluation of the effect of Zinc Acetate Solution on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. Erythromycin with or without additional Zinc Acetate Solution is used topically in the treatment of acne vulgaris. A potential effect of zinc on the stratum corneum penetration of erythromycin was investigated in human volunteers. Skin surface washings and tape strippings from the skin of the back were collected after drug applications in 12 subjects for quantification of erythromycin levels. Zinc Acetate Solution increased the amount remaining on the back skin at 6 h after application from 40 +/- 19 to 56 +/- 15% of the dose and, vice versa, reduced the amount in stratum corneum strips from 22 +/- 7 to 18 +/- 7%, both with statistical significance. The effect varied with body region. Zinc Acetate Solution thus provided to prolong the residence time of erythromycin on the skin. Product Description As an ace manufacturer and trader of Zinc Acetate Solution Solution, we have marked our name very strongly in the market. It is used to treat zinc deficiencies. As an oral daily supplement it is used to inhibit the body''s absorption of copper as part of the treatment for Wilson''s disease. Zinc Acetate Solution is also sold as an astringent in the form of an ointment, a topical lotion, or combined with an antibiotic such as erythromycin for the topical treatment of acne. It is commonly sold as a topical anti-itch ointment. Zinc Acetate Solution Sciencemadness Wiki sitesinden Zinc Acetate Solution Zinc Acetate Solution dihydrate sample.jpg Sample of Zinc Acetate Solution dihydrate Names IUPAC name Zinc Acetate Solution Zinc Acetate Solution is a chemical compound with the formula Zn(CH3COO)2 the acetic acid salt of zinc, more commonly encountered as dihydrate, Zn(CH3COO)2·2 H2O. Zinc Acetate Solution reacts with bases to form insoluble zinc hydroxide: Zn(CH3COO)2 + 2 NaOH → 2 CH3COONa + Zn(OH)2 According to one paper, pyrolysis of anhydrous Zinc Acetate Solution (at reduced pressure) should yield acetic anhydride and leave behind basic Zinc Acetate Solution: Physical Zinc Acetate Solution is a solid crystalline, soluble in water. Its anhydrous form is hygroscopic and quickly turns into the dihydrate form upon standing in open air. It has a weak acetic smell. Availability Zinc Acetate Solution is available as food supplements and can be purchased online. To obtain the pure compound, you will have to dissolve the product in water and recrystallize it from the solution. Anhydrous Zinc Acetate Solution can be prepared by heating the dihydrate or refluxing it with toluene and collecting the water with a Dean-Stark apparatus. Preparation Zinc Acetate Solution can be prepared by adding zinc metal or zinc oxide to acetic acid. 2 CH3COOH + Zn → Zn(CH3COO)2 + H2 2 CH3COOH + ZnO → Zn(CH3COO)2 + H2O Vinegar can also be used as cheap source acetic acid. After all the zinc has dissolved, the solution is concentrated and cooled to crystallize solid Zinc Acetate Solution dihydrate. If vinegar was used, organic residue from the vinegar will be trapped in the Zinc Acetate Solution crystals. To remove the impurities, crush the resulting crystals and wash them thoroughly with an organic solvent. Multiple recrystallizations might be required to remove all the impurities. If anhydrous Zinc Acetate Solution is desired, you can dry the Zinc Acetate Solution dihydrate by refluxing it with toluene, and using a Dean-Stark apparatus to separate the water. Zinc Acetate Solution is slightly irritant due to the acetic acid resulting from hydrolysis, though this is not a problem when handling the compound. Storage Zinc Acetate Solution should be stored in closed bottles, away from moisture and acids, in a well ventilated place. Anhydrous Zinc Acetate Solution should be kept in air-tight containers. Disposal No special disposal is required for Zinc Acetate Solution, though it's best to dilute it strongly if you want to pour it down the drain. Alternatively, you can precipitate zinc hydroxide/oxide by adding an alkali to a solution of Zinc Acetate Solution. References Relevant Sciencemadness threads Zinc Acetate Solution Dihydrate Quick test for Zinc Acetate Solution? Separation of Cu(OAc)2 and Zn(OAc)2 FIELD: chemistry. SUBSTANCE: invention relates to a method of producing Zinc Acetate Solution dihydrate. The method is realised by dissolving powdered zinc oxide or zinc hydroxide in aqueous acetic acid solution with ratio of reactants - zinc oxide (zinc hydroxide):water:acetic acid equal to 1:(1.6-2.0):(1.8-2.2) by weight; the obtained solution is then evaporated to oversaturation, gradually cooled to 0-5°C and held for 15-20 hours. The crystalline hydrate of Zinc Acetate Solution precipitated from the solution is filtered and dried at 30-40°C. EFFECT: improved method of producing Zinc Acetate Solution dihydrate. 3 ex The invention relates to a technology for the production of salts of acetic acid, namely, two-water Zinc Acetate Solution. The invention can also be used to obtain two-water Zinc Acetate Solution depleted in the Zn 64 isotope, which is used as an additive in cooling systems of "light-water" nuclear reactors. The use of zinc dosing technology helps to reduce the radiation dose rate during scheduled repairs, reduce the accumulation of radioactive waste in equipment, improve the corrosion state and increase the life of primary pipelines, by reducing corrosion, which ultimately increases the operating life of the equipment. Two-water Zinc Acetate Solution depleted in the Zn 64 isotope is subject to more stringent requirements for chemical purity (99.8% content of the basic substance), different from the requirements for the reagent according to GOST 5823-78 of the chemically pure grade (basic content 99.5% of the substance). The disadvantage of this method is the high drying temperature of the product, in which the two-water Zinc Acetate Solution loses water, the crystals are weathering and partially decompose. The closest in technical essence and the achieved result is a method for producing two-water Zinc Acetate Solution (Yu.V. Karyakin, I.I. Engelov. Pure chemicals. - M .: Chemistry, 1976, p. 408), in which 20 ml % aqueous solution of acetic acid, heated to a temperature of 75-80 ° C, contribute 50 g of ZnO and filtered. Next, 8-10 ml of a 3% solution of H 2 O 2 is added to the solution, heated to boiling, and a 2% solution of Ba (CH 3 COO) 2 is added dropwise until insignificant amounts of SO 4 2- remain in the solution. Next, 5 g of freshly precipitated ZnCO 3 are added to the solution, the mixture is boiled for 5 minutes, then heated for another 40-50 minutes in a water bath (to coagulate the precipitate) and filtered. CH 3 COOH was poured into the filtrate to a faint odor and cooled. The precipitated crystals are sucked off on a Buchner funnel, and the mother liquor is evaporated to form a crystalline film and crystallized. The salt is dried at room temperature. The disadvantages of this method are: the multiplicity of technological operations, low chemical purity of two-water Zinc Acetate Solution. The claimed method differs from the prototype in that: zinc oxide or zinc hydroxide powder is dissolved in an aqueous solution of acetic acid, with a reagent ratio of zinc oxide (zinc hydroxide): water: acetic acid, equal to 1: (1.6-2.0) : (1.8-2.2) by weight, the resulting solution is evaporated to supersaturation, gradually cooled to a temperature of 0-5 ° C and maintained for 15-20 hours, the precipitated Zinc Acetate Solution crystalline hydrate is filtered and dried at a temperature of 30- 40 ° C. The content of the main substance in the resulting product is at least 99.8% (wt.). Example No. 1. The powder of zinc oxide or zinc hydroxide is dissolved in an aqueous solution of acetic acid with a ratio of reagents - zinc oxide (zinc hydroxide): water: acetic acid, equal to 1: 1.6: 1.8 by weight. The resulting solution was evaporated to supersaturation, smoothly cooled to a temperature of 0-5 ° C, incubated for 15 hours. The crystallized Zinc Acetate Solution hydrate precipitated from the solution is filtered and dried at a temperature of 30 ° C. The content of the main substance in the resulting product is at least 99.8% (wt.). Example No. 2. The powder of zinc oxide or zinc hydroxide is dissolved in an aqueous solution of acetic acid at a ratio of reagents - zinc oxide (zinc hydroxide): water: acetic acid, equal to 1: 1.8: 2.0 by weight. The resulting solution was evaporated to supersaturation, smoothly cooled to a temperature of 0-5 ° C, incubated for 18 hours. The Zinc Acetate Solution crystalline hydrate precipitated from the solution is filtered and dried at a temperature of 35 ° C. The content of the main substance in the resulting product is not less than 99.8% (wt.). Example No. 3. The powder of zinc oxide or zinc hydroxide is dissolved in an aqueous solution of acetic acid at a ratio of reagents - zinc oxide (zinc hydroxide): water: acetic acid, equal to 1: 2.0: 2.2 by weight. The resulting solution was evaporated to supersaturation, gradually cooled to a temperature of 0-5 ° C, kept for 20 hours. The crystallized Zinc Acetate Solution hydrate precipitated from the solution is filtered and dried at a temperature of 40 ° C. The content of the main substance in the resulting product is at least 99.8% (wt.). When crystallization is carried out from a solution with a time of less than 15 hours, the yield of Zinc Acetate Solution does not exceed 70%. Conducting crystallization over time of more than 20 hours does not have a significant effect on increasing the yield of Zinc Acetate Solution. Carrying out drying at a temperature of less than 30 ° C increases the time of this technological stage. Drying at temperatures above 40 ° C leads to partial dehydration of crystals of two-water Zinc Acetate Solution. A method of producing a two-water Zinc Acetate Solution, characterized in that the powder of zinc oxide or zinc hydroxide is dissolved in an aqueous solution of acetic acid, with a ratio of reagents - zinc oxide (zinc hydroxide): water: acetic acid, equal to 1: (1.6-2.0 ) :( 1.8-2.2) by weight, the resulting solution was evaporated to supersaturation, gradually cooled to a temperature of 0-5 ° C and held for 15-20 hours, the precipitated Zinc Acetate Solution crystalline hydrate was filtered and dried at a temperature of 30 -40 ° C, the content of the main substance in the resulting product is not less than 99, 8 wt.%. What is Zinc Acetate Solution? Zinc Acetate Solution is used to treat and to prevent zinc deficiency. Zinc Acetate Solution may also be used for other purposes not listed in this medication guide. Important Information Before using Zinc Acetate Solution, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use Zinc Acetate Solution if you have certain medical conditions. Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb Zinc Acetate Solution. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc Acetate Solution can make certain antibiotics less effective. Tell your doctor about all other medications you are using before you start taking Zinc Acetate Solution. Before taking this medicine Before using Zinc Acetate Solution, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use Zinc Acetate Solution if you have certain medical conditions. It is not known whether Zinc Acetate Solution will harm an unborn baby. Do not take Zinc Acetate Solution without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Zinc Acetate Solution passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How should I take Zinc Acetate Solution? Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Take Zinc Acetate Solution with a full glass of water. Take Zinc Acetate Solution with food if it upsets your stomach. Your healthcare provider may occasionally change your dose to make sure you get the best results from Zinc Acetate Solution. The recommended dietary allowance of Zinc Acetate Solution increases with age. Follow your healthcare provider's instructions. You may also consult the National Academy of Sciences "Dietary Reference Intake" or the U.S. Department of Agriculture's "Dietary Reference Intake" (formerly "Recommended Daily Allowances" or RDA) listings for more information. What should I avoid while taking Zinc Acetate Solution? Avoid taking this medication with foods that are high in calcium or phosphorus, which can make it harder for your body to absorb Zinc Acetate Solution. Foods high in calcium or phosphorus include milk, cheese, yogurt, ice cream, dried beans or peas, lentils, nuts, peanut butter, beer, cola soft drinks, and hot cocoa. Zinc Acetate Solution side effects Zinc Acetate Solution side effects (in more detail) Zinc Acetate Solution dosing information -When patient is clinically stable, treatment with Zinc Acetate Solution can begin; continue chelation therapy as clinically indicated. -When patient is clinically stable, treatment with Zinc Acetate Solution can begin; continue chelation therapy as clinically indicated. What other drugs will affect Zinc Acetate Solution? The following drugs can interact with or be made less effective by Zinc Acetate Solution. Tell your doctor if you are using any of these:. This list is not complete and other drugs may interact with Zinc Acetate Solution. Tell your healthcare provider about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. See also: Zinc Acetate Solution drug interactions (in more detail) What is the most important information I should know about Zinc Acetate Solution? Before using Zinc Acetate Solution, talk to your doctor, pharmacist, herbalist, or other healthcare provider. You may not be able to use Zinc Acetate Solution if you have certain medical conditions. It is not known whether Zinc Acetate Solution will harm an unborn baby. Do not take Zinc Acetate Solution without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Zinc Acetate Solution passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Can I take Zinc Acetate Solution if I’m pregnant or breastfeeding? It is not known whether Zinc Acetate Solution will harm an unborn baby. Do not take Zinc Acetate Solution without telling your doctor if you are pregnant or could become pregnant during treatment. It is not known whether Zinc Acetate Solution passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. How to take Zinc Acetate Solution? Use Zinc Acetate Solution exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Take Zinc Acetate Solution with a full glass of water. Take Zinc Acetate Solution with food if it upsets your stomach. Zinc Acetate Solution Uses of Zinc Acetate Solution Zinc Acetate Solution is used in the treatment of: Zinc Acetate Solution Brand Names Zinc Acetate Solution may be found in some form under the following brand names: Zinc Acetate Solution Drug Class Zinc Acetate Solution is part of the drug class: Various alimentary tract and metabolism products Zinc Acetate Solution Interactions This is not a complete list of Zinc Acetate Solutiondrug interactions. Ask your doctor or pharmacist for more information. Zinc Acetate Solution and Pregnancy Tell your doctor if you are pregnant or plan to become pregnant. The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy. Zinc Acetate Solution falls into category A: When pregnant women used Zinc Acetate Solution, their babies did not show any problems related to this medication. Zinc Acetate Solution Dosage Take Zinc Acetate Solution exactly as prescribed by your doctor. Follow the directions on your prescription label carefully. The Zinc Acetate Solution dose your doctor recommends will be based on the following (use any or all that apply): Zinc Acetate Solution is available in the following doses: Antipyrine/benzocaine/Zinc Acetate Solution Otic 54 Mg-10 Mg-10 Mg/ml Otic Solution Benzyl Alcohol-Zinc Acetate Solution Topical 10%-2% Topical Cream Benzyl Alcohol-Zinc Acetate Solution Topical 10%-2% Topical Lotion Chloroxylenol/pramoxine/Zinc Acetate Solution Otic 0.1%-0.5%-0.1% Otic Drops Chloroxylenol/pramoxine/Zinc Acetate Solution Otic 0.1%-1%-1% Otic Drops Diphenhydramine Topical 1% Topical Gel Diphenhydramine Topical 2% Topical Stick Diphenhydramine-Zinc Acetate Solution Topical 1%-0.1% Topical Cream Diphenhydramine-Zinc Acetate Solution Topical 2%-0.1% Topical Cream Diphenhydramine-Zinc Acetate Solution Topical 2%-0.1% Topical Spray Diphenhydramine-Zinc Acetate Solution Topical 2%-0.1% Topical Stick Pramoxine Topical Topical Lotion Pramoxine-Zinc Acetate Solution Topical 1%-0.1% Topical Lotion Zinc Acetate Solution 25 Mg Oral Capsule Zinc Acetate Solution 50 Mg Oral Capsule Zinc Acetate Solution Compounding Powder Zinc Acetate Solution Topical 2% Topical Lotion Forms of Medication Zinc Acetate Solution is available in the following forms:
ZINC ASPARTATE
Boric acid, zinc salt; Borsäure, Zinksalz (German); ácido bórico, sal de cinc (Spanish); Acide borique, sel de zinc (French); cas no: 1332-07-6
ZINC BORATE
Zinc borate is a fine white powder that is slightly soluble in water, and has good thermal stability.
Zinc borate is an inorganic compound that presents as a white crystalline powder.
Zinc Borate is an inorganic compound used as a flame retardant and a smoke suppressant for a wide range of plastics, rubbers, paper and textiles.


CAS Number: 1332-07-6
tetrahydrate: 12513-27-8
B6O18Zn9: 12280-01-2
Molecular Formula: B2O6Zn3


Zinc Borate's chemical formula is xZnO.yB2O3zH2O.
Zinc Borate is a chemical substance used as a smoke suppressor and
contains boron within it.


Zinc Borate is a white, non-damp, viscous and powdery substance.
Zinc borate is one of the most important properties of zinc borate because it has low water solubility and high dehydration temperature.
Zinc Borate is also possible to add solid polymer additives by squeezing or spraying molding.


Zinc Borate can only be hydrolysis with strong acids and bases.
Zinc Borate is also a substance that confers adhesion and anti-art properties between metals and resins.
Zinc Borate’s insoluble in water.


Several variants of zinc borate exist with different zinc/boron ratios and water contents.
Zinc borate has low toxicity and isn’t considered hazardous.
The fire-retardant properties of zinc borate form the foundation for many of its uses in industry.


Still, Zinc Borate also has many other useful characteristics.
Zinc borate is found in plastics and cellulose fibres, paints and fungicides.
Zinc Borate is non-toxic, low-water-soluble, has high heat stability, and small particle size with good dispersion characteristics.


Zinc Borate is a versatile compound with many different applications.
Zinc Borate meets the stringent fire legislation in terms of flame, smoke and processing.
Zinc Borate is a non-toxic, low-water-soluble and has a high heat stability.


Zinc Borate reduces smoke emissions depending on the formulation and promotes charring which can lead to lower overall filler loadings.
Zinc Borate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 to < 100 tonnes per annum.


Zinc borate is an inorganic compound, a borate of zinc.
Zinc Borate is a white crystalline or amorphous powder insoluble in water.


Several variants of zinc borate exist, differing by the zinc/boron ratio and the water content:
*Zinc borate Firebrake ZB (2ZnO·3 B2O3·3.5H2O), CAS number 138265-88-0
*Zinc borate Firebrake 500 (2ZnO·3 B2O3), CAS number 138265-88-0
*Zinc borate Firebrake 415 (4ZnO·B2O3·H2O), CAS number 149749-62-2
*ZB-467 (4ZnO·6B2O3·7H2O), CAS number 1332-07-6
*ZB-223 (2ZnO·2B2O3·3H2O), CAS number 1332-07-6


The hydrated variants of Zinc Borate lose water between 290–415 °C.
Zinc borate appears as a white powder of variable composition. (typically 45% ZnO, 34% B2O3 and 20% H2O).
Zinc Borate is slightly soluble in water.


Zinc borate is an inorganic compound, a borate of zinc.
Zinc Borate is a white crystalline or amorphous powder insoluble in water.
Zinc Borate's toxicity is low.
Zinc Borate's melting point is 980 °C.



USES and APPLICATIONS of ZINC BORATE:
Zinc borates are used as flame retardant, corrosion retardant and smoke suppressor in polymers and coatings, especially in pvc, nylon and halogenated polyester.
Zinc Borate is used in the manufacture of high temperature resistant plastics as it has a high dehydration temperature.


Zinc borates have areas of use in in fireproof cables, fireproof fabrics, electrical-electronic components, paints, automobile-aircraft interior parts, paper and textile industry.
Zinc Borate is often preferred because it is a more effective smoke suppressor when compared to other flame retardants and is cheaper than other flame retardants.


In recent years, the use of zinc borate in combination with other flame retardants in different applications has been increasing.
For example, zinc borate is used in combination with aluminum hydroxyl and magnesium hydroxyl in halogen-containing and non-containing systems.
Zinc borate is also used to reduce melting point in glass and ceramic industry, as well as to protect wood components as fungus and insecticide in addition to the use of flame retardant.


Zinc Borate is widely used as a less toxic alternative to antimony (III) oxide.
Zinc Borate is used as a corrosion inhibitor, fire retardant, infrared absorber and fungicide in wood preservation.
Zinc Borate can be used in the manufacture of coatings, plastics, coatings, cables, flame retardants and smoke suppressants.


Applications of Zinc Borate: flame retardant synergist for PP, PE,TPO, EPDM, PVC, HIPS, ABS, PC/ABS, PPO, HIPS, Polyester, Phenolic resin, PA, HTPA, PC, Coating – Paint, Textile – Back Coating, Adhesive, RUBBER, SILICONE, PE/EVA XLPE/EVA – SMC/BMC
Zinc Borate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Other release to the environment of Zinc Borate is likely to occur from: indoor use, outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Other release to the environment of Zinc Borate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Zinc Borate can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).


Zinc Borate is used in the following products: coating products, fertilisers, heat transfer fluids, hydraulic fluids, lubricants and greases and polymers.
Zinc Borate is used in the following areas: agriculture, forestry and fishing.
Zinc Borate is used in the following products: adhesives and sealants, coating products and lubricants and greases.


Other release to the environment of Zinc Borate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Zinc Borate is used in the following products: adhesives and sealants, coating products, fertilisers, lubricants and greases and polymers.
Zinc Borate can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).


Release to the environment of Zinc Borate can occur from industrial use: formulation of mixtures and formulation in materials.
Zinc Borate is used in the following products: adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids, lubricants and greases and polymers.


Zinc Borate is used in the following areas: building & construction work.
Release to the environment of Zinc Borate can occur from industrial use: in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.


Release to the environment of Zinc Boratee can occur from industrial use: manufacturing of the substance.
Zinc Borate is a low toxicity, white crystalline, inorganic compound primarily used as a flame retardant and smoke suppressant in plastics and cellulose fibers, paper, rubbers and textiles.


Zinc Borate is also used in paints, adhesives and pigments.
As a flame retardant, zinc borate can replace antimony trioxide as a synergist in both halogen-based and halogen-free systems.
Zinc Borate is also used as a flame retardant in vinyl chloride latex formulations and as an adhesive in bonding fiberglass insulation to aluminum foil.


Zinc Borate is a highly effective flame retardant that is widely used in plastics, rubber, paint and other products.
Zinc borates have many uses.
The flame-retardant and smoke suppression properties make Zinc Borate ideal for polymers and polyamides.


Zinc Borate also finds use in paper, rubbers and textiles for the same characteristics.
The agricultural industry uses zinc borate as plant nutrition.
Zinc Borate also finds use as a fungicide and to prolong the life of the wood.


Zinc Borate’s beneficial in cables and insulators and as an arc suppressant.
Zinc Borate even finds use in lubricants to improve friction properties.
This versatile mineral, Zinc Borate, has uses in almost every industry.


Zinc Borate is a low-toxicity, a white crystalline, inorganic compound primarily used as a flame retardant and smoke suppressant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc Borate is also used in paints, adhesives and pigments.


Zinc Borate can also be used in paints, adhesives, pigments and ceramic industrial applications.
Zinc Borate acts as a synergistic flame retardant with antimony oxide. Zinc Borate has the smallest particle size.
Zinc Borate reduces smoke evolution and adjust the balance of flame retardant properties versus mechanical, electrical and other properties.


Zinc Borate is compatible with PVC, nylon, PE, PP, polyesters, epoxy, thermoplastic elastomers and rubbers.
Zinc Borate is suitable for use in carpet, conveyor belt, wire and cable in PVC.
Zinc Borate is widely used as a flame retardant and smoke suppressant in the industry for plastic.


Zinc Borate is also used in adhesives, pigments and paints.
Zinc Borate function as a synergist in plastics and rubber.
Zinc Borate is used as a fungus and mildew inhibitor, to fireproof textiles, and for other uses Dry Powder, Other Solid, Pellets Large Crystals.


Zinc Borate is used Wires & Cables, Paints & Coatings, Rubber Applications, Electronics, and Adhesives & Sealants.
Zinc Borate upgrades the thermal stability and UV stabilization of the flame retardant in polymer formulations and acts as a great smoke suppressant by promoting char formation.


Thanks to its high dehydration temperature, Zinc Borate is used in production of high temperature resistant polymers.
Zinc Borate can be used in both halogen-containing and halogen-free flame retardant formulations.
Zinc Borate is used in a wide range of applications such as plastics, rubber, paints, adhesives, pigments, etc.


Zinc Borate synergizes with other flame retardants, such as ATH, MDH and others by increasing their activity, performance and mechanical properties.
For most flame retardant formulations where antimony oxide is used, it shows that Zinc Borate replaced with antimony oxide, whether partially or wholly, improves the performance and smoke suppression in addition to being more cost-efficient than antimony oxide.


Zinc Borate is a Boron based flame retardant compatible with many polymeric matrices.
Zinc Borate is effective both in the solid phase and in the gas phase and its strong smoke suppressing action, helps to improve time of rescue in case of fire.


Zinc Borate is a multifunctional flame retardant.
Zinc Borate promotes the formation of a protective vitreous layer and of a strong char layer, which reduces the formation of toxic and irritant smoke during the fire


Zinc Borate looses its water of hydration at temperatures above 290°C, cooling the front of the flames and subtracting energy to the fire
Zinc Borate acts as a synergist in conjunction with halogenated compounds, so that lower loadings of halogenated flame retardant additives are needed
Zinc Borate shows a strong synergic effect with antimony trioxide; in presence of alumina trihydrate (ATH) the synergic effect is enhanced


Zinc Borate improves resistance against electrical degradation: high anti-arcing and anti-tracking indexes.
Zinc Borate is an afterglow suppressant.
Zinc borate is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.


Zinc Borate is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc Borate can replace antimony trioxide as a synergist in both halogen-based and halogen-free systems.
Zinc Borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.


In electrical insulator plastics Zinc Borate suppresses arcing and tracking.
In halogen-containing systems, zinc borate is used together with antimony trioxide and alumina trihydrate.
Zinc Borate catalyzes formation of char and creates a protective layer of glass.


Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.
In halogen-free system, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.
During burning the plastics, a porous borate ceramics is formed that protects the underlying layers.


In presence of silica, borosilicate glass can be formed at plastic burning temperatures.
Zinc borate is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.
Zinc Borate is also used in some intumescent systems.


Zinc borate has synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.
Zinc borate acts as a broad-spectrum fungicide in plastics and wood products.
Zinc borate can be used as a flux in some ceramics. In electrical insulators it improves the ceramics properties.


Nanopowder zinc borate can be used for the applications above, and also for improving the frictional properties of lubricating oils.
Zinc borate is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc Borate is also used in paints, adhesives, and pigments.


As a flame retardant, Zinc Borate can replace antimony(III) oxide as a synergist in both halogen-based and halogen-free systems.
Zinc Borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc Borate suppresses arcing and tracking.


In halogen-containing systems, zinc borate is used together with antimony trioxide and alumina trihydrate.
Zinc Borate catalyzes the formation of char and creates a protective layer of glass.
Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.


In halogen-free system, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.
During burning the plastics, a porous borate ceramics is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.


Zinc borate is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.
Zinc Borate is also used in some intumescent systems.
Zinc borate has synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.


Zinc borate acts as a broad-spectrum fungicide in plastics and wood products.
Zinc borate can be used as a flux in some ceramics.
In electrical insulators it improves the ceramics properties.


Nanopowder zinc borate can be used for the applications above, and also for improving the frictional properties of lubricating oils.
Zinc Borate is used as a fungus and mildew inhibitor, to fire proof textiles, and for other uses.
Due to its flame retardant, smoke suppressing and antibacterial properties and halogen-free properties, Zinc Borate has been the raw material sought in the rubber and plastic industry in recent years.


Zinc Borate works in harmony with other non-flammability chemicals in systems containing and not containing halogen.
Zinc Borate has been used increasingly in conjunction with ATH.
In addition, zinc borate can be used in combination with antimony trioxide or alone.
Zinc Borate is generally immediately available in most volumes.


-Polymer Applications of Zinc Borate:
*Polyvinyl chloride
*Epoxy
*Polyethylene
*Polypropylene
*Polyesters
*Elastomers
*Polyamide (nylon)
*Polyolefin
*Acrylics
*Phenolics
*TPE
*Silicones


-Paints, Pigments And Adhesives:
The flame-retardant and smoke-suppressing properties of zinc borate define how it’s primarily used in paints, adhesives, and pigments.
In combination with zinc phosphate or barium phosphate, Zinc Borate acts as a corrosion inhibiting pigment.


-Polymers:
*Halogen containing systems:
Zinc boride acts as a char promoting agent.
The zinc boride forms a protective layer of glass.
Here, zinc borate works with antimony trioxide and alumina trihydrate.
Zinc borate also has anti-drip properties.

*Halogen-free systems:
Zinc borate works with alumina trihydrate, magnesium hydroxide, red phosphorus or ammonium polyphosphate to do the same.
As the plastics burn, a porous boron ceramic is formed, protecting the layers beneath.
Halogen-free systems show better flame retardant properties.

-Polyamides:
Polyamide plastics have many useful properties.
The heat, smoke and toxic gas from the burning of polyamides hinder their use.
As polyamides consist of strings of polymers, the same flame retardant and smoke suppressant properties apply.
Phosphinate-based and halogen-free electrical insulator plastics use zinc borate.
Alumina trihydrate, magnesium hydroxide and red phosphorus work with zinc borate in these plastics.
The zinc boride acts as a char promoting agent and suppresses afterglow.


-Agriculture:
The agriculture sector uses zinc borates to increase crop yields and prevent plant diseases.
Some micronutrient formulations also use Zinc Borate in their fertilisers.


-Other Uses:
Zinc borate is also used as a flame suppressant in cellulose fibres, paper, rubbers and textiles.
Other uses of Zinc Borate include a wood treatment for fungus control and to improve the friction properties in lubricants.
Zinc Borate also finds use as an adhesive in bonding aluminium foil and fibreglass.
Zinc Borate even finds use in insulating ceramics as flux.
Zinc Borate also has the effect of reducing firing time and temperatures for ceramics.
For this reason, Zinc Borate’s often used in the manufacture of bricks and porcelain.



IN WHICH AREAS IS ZINC BORATE USED?
Certain areas where zinc borate can be used are as follows;
*In production of automobile / aircraft interior components
*Electrical / electronic parts production
*PVC coatings
*Fire retardant and fire extinguisher production sectors
*In the fungal and insecticide pharmaceutical Industries
*At the textile and plastics Institute
*Cable industry



VARIANTS OF ZINC BORATE:
Several variants of zinc borate exist, differing by the zinc/boron ratio and the water content:
Zinc borate Firebrake ZB (2ZnO·3 B2O3·3.5H2O), CAS number 138265-88-0
Zinc borate Firebrake 500 (2ZnO·3 B2O3), CAS number 12767-90-7
Zinc borate Firebrake 415 (4ZnO·B2O3·H2O), CAS number 149749-62-2
ZB-467 (4ZnO·6B2O3·7H2O), CAS number 1332-07-6
ZB-223 (2ZnO·2B2O3·3H2O), CAS number 1332-07-6
The hydrated variants lose water between 290–415 °C.



PHYSICAL and CHEMICAL PROPERTIES of ZINC BORATE:
Molecular Weight: 313.8 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 311.77242 g/mol
Monoisotopic Mass: 309.77552 g/mol
Topological Polar Surface Area: 138Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes

Compound Formula: B2O6Zn3
Molecular Weight: 313.7584 g/mol
Appearance: White solid
Melting Point: 980 °C
Boiling Point: N/A
Density: 3.64 g/cm3
Solubility in H2O: N/A
Exact Mass: 311.772416 g/mol
Monoisotopic Mass: 309.775525 g/mol
CAS Number: 12513-27-8
Assay (purity): 95%
Purity method: by elemental analysis
Molecular weight: 434.69
Form: solid
Appearance: white powder
Melting point: 650C
Molecular formula: 2ZnO · 3B2O3 · 3.5H2O
Linear formula: 2ZnO · 3B2O3 · 3.5H2O

IUPAC Nametrizinc: diborate
Molecular Weight: 313.8g/mol
Molecular Formula: B2O6Zn3
SMILES: B([O-])([O-])[O-].B([O-])([O-])[O-].[Zn+2].[Zn+2].[Zn+2]
InChI: InChI=1S/2BO3.3Zn/c2*2-1(3)4;;;/q2*-3;3*+2
InChIKey: BIKXLKXABVUSMH-UHFFFAOYSA-N
Melting Point: 980°C
Density: 3.64 g/cm³ (20°C)
Solubility: Soluble in dilute acids; slightly soluble in water;0.3% in water at 20 °C
Appearance: White solid
Color/Form: White, amorphous powder;White granular
Complexity: 8
Covalently-Bonded Unit Count: 5
EC Number: 215-566-6;238-763-9
Exact Mass: 311.77242g/mol
Formal Charge: 0
Heavy Atom Count: 11
Monoisotopic Mass: 309.77552g/mol
Odor: None



FIRST AID MEASURES of ZINC BORATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC BORATE:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC BORATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
-Further information:
The product itself does not burn.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC BORATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.



HANDLING and STORAGE of ZINC BORATE:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC BORATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
10361-94-1
1332-07-6
21LB2V459E
Alcanex FR 100
Alcanex FRC 600
B-H3-O3.x-Zn
BH3O3.xZn
Bonrex FC
Borax 2335
Boric acid (H6B4O9), zinc salt (1:3)
Boric acid (HBO2), zinc salt (2:1)
Climax ZB 467
D,L-ASPARTICACIDDIBENZYLESTER-P-TOLUENESULFONATE
Diboron zinc tetraoxide
DTXSID6091554
EINECS 215-566-6
EINECS 238-763-9
Firebrake ZB 2335
Flamtard Z 10
FRC 600
FT-0726070
HSDB 1046
JS 9502
Q27253563
SZB 2335
trizinc;diborate
UNII-21LB2V459E
XPI 187
ZB 112
ZB 237
ZB 467 Lite
ZINC BORATE
ZINC BORATE [HSDB]
ZINC BORATE [INCI]
ZINC BORATE [WHO-DD]
ZINC BORATE OXIDE 3.5 HYDRATE
zinc(II) borate
ZN 100
ZSB 2335
ZT (fire retardant)


ZINC BORATE
Zinc borate is an inorganic compound, a borate of zinc.
Zinc borate is a white crystalline or amorphous powder insoluble in water.
Zinc borate's toxicity is low.

CAS: 1332-07-6
MF: B2O6Zn3
MW: 313.79
EINECS: 215-566-6

Synonyms
Zinc borate;ZINC BORATE OXIDE 3.5 HYDRATE;ZINC BORATE 3.5 HYDRATE;Firebrake ZB;Zinc Borate, HeMiheptahydrate;Zinc Borate,Fiame Retardant;borax2335;flameretardantzb;ZINC BORATE;10361-94-1;trizinc;diborate;Firebrake ZB;21LB2V459E;Diboron zinc tetraoxide;Bonrex FC;zinc(II) borate;Flamtard Z 10;ZT (fire retardant);Alcanex FR 100;Alcanex FRC 600;Climax ZB 467;Firebrake ZB 2335;Borax 2335;ZB 467 Lite;ZINC BORATE [HSDB];ZINC BORATE [INCI];UNII-21LB2V459E;ZINC BORATE [WHO-DD];DTXSID6091554;HSDB 1046;FRC 600;XPI 187;BIKXLKXABVUSMH-UHFFFAOYSA-N;SZB 2335;ZSB 2335;EINECS 215-566-6;EINECS 238-763-9;ZB 112;ZB 237;ZN 100;JS 9502;Boric acid (HBO2), zinc salt (2:1);FT-0726070;NS00075651;D,L-ASPARTICACIDDIBENZYLESTER-P-TOLUENESULFONATE;Q27253563

Zinc borate's melting point is 980 °C.
Zinc borate is a Boron based flame retardant compatible with many polymeric matrices.
Zinc borate is effective both in the solid phase and in the gas phase and its strong smoke suppressing action, helps to improve time of rescue in case of fire.
Zinc borate is a multifunctional flame retardant:
promotes the formation of a protective vitreous layer and of a strong char layer, which reduces the formation of toxic and irritant smoke during the fire,
Zinc borate looses its water of hydration at temperatures above 290°C, cooling the front of the flames and subtracting energy to the fire,
Zinc borate acts as a synergist in conjunction with halogenated compounds, so that lower loadings of halogenated flame retardant additives are needed,
Zinc borate shows a strong synergic effect with antimony trioxide; in presence of alumina trihydrate (ATH) the synergic effect is enhanced,
Zinc borate improves resistance against electrical degradation: high anti-arcing and anti-tracking indexes
Zinc borate is an afterglow suppressant.

Zinc borate is an inorganic compound that presents as a white crystalline powder.
Zinc borate’s insoluble in water.
Several variants of zinc borate exist with different zinc/boron ratios and water contents.
Zinc borate has low toxicity and isn’t considered hazardous.
The fire-retardant properties of zinc borate form the foundation for many of its uses in industry.
Still, Zinc borate also has many other useful characteristics.
Zinc borate is found in plastics and cellulose fibres, paints and fungicides.
Bisley supplies zinc borate to diverse sectors worldwide.

TCC’s Zinc borate is an Environmental Protection Agency (EPA) approved non-halogen flame retardant.
Zinc borate can be used as a fire retardant in PVC, polyolefins, elastomers, polyamides, and epoxy resins.
In halogen-containing systems, Zinc borate is used in conjunction with antimony oxide.
In halogen-free systems, Zinc borate is normally used in conjunction with alumina trihydrate, magnesium hydroxide, or red phosphorus.
In some particular applications, zinc borate can be used alone.
Zinc borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc borate suppresses arcing and tracking.
Zinc borate has a synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.

Zinc borate acts as a broad-spectrum fungicide in plastics and wood products.
Zinc borate can be used as a flux in some ceramics.
In electrical insulators, Zinc borate improves the ceramics properties.
Zinc borate has a refractive index similar to most polymer systems, which results in the retention of considerable translucence.
This allows the use of lower pigment loading as compared to antimony oxide.
Zinc borate has a specific gravity of 2.77 and is considered to be low toxicity.
The most commonly used variety of zinc borate is 3.5 water zinc, also known as ZB-2335 flame retardant.
Zinc borate is a halogen-free, inorganic boron based multifunctional flame retardant.
Zinc borate is non-toxic, has excellent dispersibility in a number of different polymer systems and shows high thermal stability.

Zinc borate is used in paints, adhesives, plastics, cellulose fibres , rubbers and textiles.
As a flame retardant, Zinc borate loses its water of hydration at temperatures above 290°C, cooling the front of the flames and subtracting energy to the fire and Zinc borate can replace levels of antimony trioxide as a synergist in both halogen-based and halogen-free systems.
In halogen-containing systems, zinc borate can be used together with antimony trioxide and alumina trihydrate where it shows a strong synergistic effect.
Here Zinc borate catalyses the formation of char and creates a protective layer of glass.
Zinc borate also acts as a synergist in conjunction with other halogenated compounds, so that lower loadings of halogenated flame retardant additives are required.
In halogen-free systems, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate. .
Additionally Zinc borate is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.
Zinc borate is also used in some intumescent systems.

Zinc borate Chemical Properties
Melting point: 980 °C
Density: 3.64 g/cm3
LogP: -0.292 (est)
CAS DataBase Reference: 1332-07-6(CAS DataBase Reference)
EPA Substance Registry System: Zinc borate (1332-07-6)

Uses
Zinc borate is prepared as an insoluble double salt from water-soluble zinc and boron compounds.
Compounds having varying amounts of zinc, boron, and water of hydration are available.
The ratio of these components affects the temperature at which the flame-inhibiting powers are activated, as well as the temperature at which they can be processed.
Zinc borates can either be used alone or in combination with other halogen synergists, such as antimony oxide.
In some instances zinc borate is also used with alumina trihydrate to form a glass-like substance that inhibits polymer degradation.
Medicine, fireproofing textiles, fungistat and mildew inhibitor, flux in ceramics.

zinc borate is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc borate is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc borate can replace antimony trioxide as a synergist in both halogen-based and halogen-free systems.
Zinc borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc borate suppresses arcing and tracking.
In halogen-containing systems Zinc borate is used together with antimony trioxide and alumina trihydrate.

Zinc borate catalyzes formation of char and creates a protective layer of glass.
Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.
In halogen-free systems, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.
When burning the plastics, a porous borate ceramic is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.
As the partial, or completely EPA approved substitute for containing halogen and other flame retardants, zinc borate is being directly applied to a wide range of plastics and rubber processing such as PVC, PE, PP, and to enhance polyamide, PVC resin, polyphenylene ethylene, epoxy resin, polyester resin, acid ethylene and natural rubber, styrene butadiene rubber, and chloroprene rubber.
Zinc borate can also be applied to the production of paper, fiber fabric, decorative panels, floor leather, wallpaper, carpet, ceramic glaze, fungicides, and paint production to improve flame retardant performance.

Zinc borate is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc borate is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc borate can replace antimony(III) oxide as a synergist in both halogen-based and halogen-free systems.
Zinc borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc borate suppresses arcing and tracking.
In halogen-containing systems, zinc borate is used together with antimony trioxide and alumina trihydrate.
Zinc borate catalyzes formation of char and creates a protective layer of glass.
Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.
In halogen-free system, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.

During burning the plastics, a porous borate ceramics is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.
Zinc borate is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.
Zinc borate is also used in some intumescent systems.
Zinc borate has synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.
Zinc borate acts as a broad-spectrum fungicide in plastics and wood products.
Zinc borate can be used as a flux in some ceramics.
In electrical insulators Zinc borate improves the ceramics properties.
Nanopowder zinc borate can be used for the applications above, and also for improving the frictional properties of lubricating oils.

Zinc borate is also used as a flame suppressant in cellulose fibres, paper, rubbers and textiles.
Other uses include a wood treatment for fungus control and to improve the friction properties in lubricants.
Zinc borate also finds use as an adhesive in bonding aluminium foil and fibreglass.
Zinc borate even finds use in insulating ceramics as flux.
Zinc borate also has the effect of reducing firing time and temperatures for ceramics.
For this reason, Zinc borate’s often used in the manufacture of bricks and porcelain.

Industrial uses
zinc borate (2ZnO-3B2Ovl5H2O) has a greater flame retardancy than borates used alone.
Zinc borate perform most of their flame retardant function in the condensed phase.
Zinc borate is used with boron in the form of zinc borate, and with molybdenum in the form of zinc molybdate.
Zinc borate can also be used as a flame retardant and smoke suppressant with different polymers.
In the case of zinc borate, 2ZnO.3B203.3.5H20, water given off can promote the formation of a cellular char which can act as a good insulator in protecting the underlying polymer or substrate.
Moore studied the effects of zinc borate on smoke reduction and flame retardancy of PVC.
He reported that smoke generation can be suppressed by over 40% by proper combination of additives without an adverse effect on flame retardancy.
The use of zinc borate as a flame retardant and smoke suppressant alone or with other additives, e.g. Sb203, or AI(OH)3, has found wide application in the plastics industry.

Production Methods
Zinc borate (2ZnO·3B2O3·3.5H2O) in general is produced with the reaction between zinc oxide and boric acid.
Boric acid is solved in water between temperatures 95ºC and 98ºC and zinc oxide and seed crystal of 2ZnO·3B2O3·3.5H2O is added to this solution at a certain stoichiometric ratio.
The reaction continues for a while by mixing and the zinc borate formed is filtered, dried and ground.
The boric acid solution is fed to the system as reflux.
ZINC BORATE
Zinc borate is a chemical compound of zinc and boron.
Zinc Borate is a white crystalline or amorphous powder insoluble in water.


CAS Number: 1332-07-6
tetrahydrate: 12513-27-8
B6O18Zn9: 12280-01-2
Molecular Formula: B2O6Zn3



SYNONYMS:
ZINC BORATE, 10361-94-1, 1332-07-6, trizinc;diborate, Firebrake ZB, 21LB2V459E, Diboron zinc tetraoxide, Bonrex FC, zinc(II) borate, Flamtard Z 10, ZT (fire retardant), Alcanex FR 100, Alcanex FRC 600, Climax ZB 467, Firebrake ZB 2335, Borax 2335, ZB 467 Lite, ZINC BORATE [HSDB], UNII-21LB2V459E, ZINC BORATE [WHO-DD], DTXSID6091554, HSDB 1046, FRC 600, XPI 187, SZB 2335, ZSB 2335, EINECS 215-566-6, EINECS 238-763-9, ZB 112, ZB 237, ZN 100, JS 9502, Boric acid (HBO2), zinc salt (2:1), DB-372151, NS00075651, Q27253563, 10361-94-1, 1332-07-6, 21LB2V459E, Alcanex FR 100, Alcanex FRC 600, B-H3-O3.x-Zn, BH3O3.xZn, Bonrex FC, Borax 2335, Boric acid (H6B4O9), zinc salt (1:3), Boric acid (HBO2), zinc salt (2:1), Climax ZB 467, D,L-ASPARTICACIDDIBENZYLESTER-P-TOLUENESULFONATE, Diboron zinc tetraoxide, DTXSID6091554, EINECS 215-566-6, EINECS 238-763-9, Firebrake ZB 2335, Flamtard Z 10, FRC 600, FT-0726070, HSDB 1046, JS 9502, Q27253563, SZB 2335, trizinc;diborate, UNII-21LB2V459E, XPI 187, ZB 112, ZB 237, ZB 467 Lite, ZINC BORATE, ZINC BORATE [HSDB], ZINC BORATE [INCI], ZINC BORATE [WHO-DD], ZINC BORATE OXIDE 3.5 HYDRATE, zinc(II) borate, ZN 100, ZSB 2335, ZT (fire retardant), Alcanex FR 100, Alcanex FRC 600, Bonrex FC, Boric acid, zinc salt, Climax ZB 467, Firebrake ZB, Firebrake ZB 500, Flamtard Z 10, ZB 467 Lite, Zinc boric acid, Boric acid zinc salt, Zinc orthoborate, Orthoboric acid zinc salt, Firebrake ZB, Firebrake 500, Firebrake 415, CAS 138265-88-0, CAS 149749-62-2, ZB-467, ZB-223, CAS 1332-07-6, diboron trizinc hexaoxide, CAS 10192-46-8, CAS 12767-90-7, CAS 12536-65-1, Firebrake ZB, Zinc Borate, HeMiheptahydrate, zn100, zb237, zb112, borax2335, Zinc borate, ZincBoratePure, flameretardantzb, Borsure, Zinksalz, ZB2335, Borate Flame Retardant, Diboron zinc tetraoxide, Zinc borate, Zin fluoroberate, Zinc borate powder, Boric acid zinc salt, Orthoborsure, Zinksalz, orthoboric acid, zinc salt, Boric acid/zinc,(1:x) salt, Zinc borate powder (Zn3BO6), ZINC BORATE LIGHT, TECHNICAL, Boric acid (H3BO3), zinc salt



Zinc borate is an inorganic compound, a borate of zinc.
Zinc Borate is a white crystalline or amorphous powder insoluble in water.
Zinc Borate's melting point is 980 °C.


Zinc Borate is an inorganic compound that exists in the form of white crystals or amorphous powder, insoluble in water, has low toxicity, melting point 980 °C.
Zinc Borate is an environmentally friendly halogen-free flame retardant, formula xZnO.yB2O3.zH2O, where zinc borate with 3,5 hydrate called ZB-2335 (2ZnO.3B2O33.5H2O) is the one used most commonly used.


Zinc Borate has possessed some excellent properties of non-toxicity, good thermal stability, fine particle size, low specific gravity….
Zinc borate, which delays the flame, allows the formation of a safe zone.
In the event of a possible fire, Zinc Borate helps to keep the loss of life and property to a minimum, thus providing time for human intervention.


Zinc Borate is produced with borate does not pose a threat to human health, providing a longer and longer shelf life in application areas than chemical products.
Zinc Borate meets the stringent fire legislation in terms of flame, smoke and processing.


Zinc Borate is a non-toxic, low-water-soluble and has a high heat stability.
Zinc Borate reduces smoke emissions depending on the formulation and promotes charring which can lead to lower overall filler loadings.
Zinc borate is a chemical compound of zinc and boron.


Zinc is a metallic element with the atomic number 30.
Zinc Borate is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts Zinc Borate is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc Borate belongs to the class of inorganic compounds known as transition metal borates.
These are inorganic compounds in which the largest oxoanion is borate, and in which the heaviest atom not in an oxoanion is a transition metal.
Zinc borate is an inorganic compound, a borate of zinc.


Zinc Borate is a white crystalline or amorphous powder insoluble in water.
Zinc Borate's melting point is 980 °C.
Zinc borate has synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.


Zinc borate acts as a broad-spectrum fungicide in plastics and wood products.
Zinc Borate's chemical formula is xZnO.yB2O3zH2O.
Zinc Borate is a chemical substance used as a smoke suppressor and contains boron within it.


Zinc Borate is a white, non-damp, viscous and powdery substance.
Zinc borate is one of the most important properties of zinc borate because it has low water solubility and high dehydration temperature.
Zinc Borate is also possible to add solid polymer additives by squeezing or spraying molding.


Zinc Borate can only be hydrolysis with strong acids and bases.
Zinc Borate is also a substance that confers adhesion and anti-art properties between metals and resins.
Zinc borate is an inorganic compound that presents as a white crystalline powder.


Zinc Borateinsoluble in water.
Several variants of zinc borate exist with different zinc/boron ratios and water contents.
Zinc borate has low toxicity and isn’t considered hazardous.


The fire-retardant properties of zinc borate form the foundation for many of its uses in industry.
Zinc borate appears as a white powder of variable composition. (typically 45% ZnO, 34% B2O3 and 20% H2O).
Zinc Borate is slightly soluble in water.


The primary hazard is the threat to the environment.
Immediate steps should be taken to limit its spread to the environment.
Zinc borate is a fine white powder that is slightly soluble in water, has good thermal stability and low human toxicity.


Zinc Borate is widely used as a less toxic alternative to antimony (III) oxide.
Zinc Borate is generally immediately available in most volumes.
Zinc Borate is an inorganic compound used as a flame retardant and a smoke suppressant for wide range of plastics, rubbers, paper and textiles, it can also be used in paints, adhesives, pigments and ceramic industrial applications.


Zinc Borate meets the stringent fire legislation in terms of flame, smoke and processing.
Zinc Borate is a non-toxic, low-water-soluble and has a high heat stability.
Zinc Borate reduces smoke emissions depending on the formulation and promotes charring which can lead to lower overall filler loadings.


Zinc borate is a low toxicity, white crystalline, inorganic compound primarily used as a flame retardant and smoke suppressant in plastics and cellulose fibers, paper, rubbers and textiles.
As a flame retardant, zinc borate can replace antimony trioxide as a synergist in both halogen-based and halogen-free systems.


Zinc Borate is non-toxic, low-water-soluble, has high heat stability, and small particle size with good dispersion characteristics.
Zinc Borate is a highly effective flame retardant that is widely used in plastics, rubber, paint and other products
Zinc Borate is a zinc containing flame retardant:


Zinc compounds were initially developed as smoke suppressants for PVC.
Later Zinc Borate was found that they also act as flame retardants in certain plastics mainly by promoting char formation.
Zinc Borate is a versatile and effective compound widely used to enhance materials' fire resistance and durability in various industries.


Its multifunctional properties and relatively low toxicity make Zinc Borate a popular choice for improving safety and performance.
Zinc borate is flame retardant and smoke suppressant.
Zinc borate is compatible with polyamides, PVC, polyethylene, polypropylene, epoxy, polyesters, elastomers and rubber based formulations.


Zinc Borate acts as a flame retardant and and smoke suppressant.
Zinc Borate appears as a white crystalline powder having molecular weight of 434.62.
Zinc borate is a non-halogenated flame retardant.


Zinc borate is useful as a flame retardant in polyethylene and PVC.
The boron functions as a flame retardant by forming trihalides which are effective Lewis acids.
The boron trihalides promote cross-linking which minimizes flammable gasses forming from the polymer.


In addition to the hydrate, zinc borate can be offered as the metaborate.
Zinc Borate’s an inorganic compound with a low toxicity used primarily as a flame retardant and smoke suppressing in plastic, fibres, paper rubbers, and textiles.


Zinc Borate’s also found in paints and fungicides and it looks like a white crystalline powder.
Zinc borate degrades endothermically, which means that it’s absorbing heat.
Zinc borate is naturally occurring but can also be synthesized and used in a wide variety of industries.


As Zinc Borate’s absorbing the heat, it will start releasing its water of hydration at about 290° Celsius.
This process helps reduce the intensity of the fire, which is why zinc borate is widely used in both based and halogen free systems.
But, we will talk about these applications at length below.



USES and APPLICATIONS of ZINC BORATE:
Zinc Borate is used as a flame retardant and a smoke suppressant for wide range of plastics, rubbers, paper and textiles, it can also be used in paints, adhesives, pigments and ceramic industrial applications.
Zinc borate is one of the eco-friendly and halogen-free flame retardants.


Zinc Borate can be used as a multi-functional synthetic additive for other halogenated flame retardants, which can improve the effectiveness of flame retardants, reduce smoke generation during combustion, and can regulate the chemical, mechanical and electrical properties of rubber and plastic products.
Zinc Borate catalyzes formation of char and creates a protective layer of glass.


Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.
Zinc Borate is used as a flame retardant in combination with other chemicals, including antioxins trioxide, magnesium hydroxide, alumina trihydrate, and some bromine flame retardants.


Zinc Borate partially or completely replaces halogen-containing flame retardants, it is widely used in plastic and rubber processing, such as PVC, PE, PP, polyamide, polyurethane, polystyrene, epoxy resin, vinyl vinyl , styrene butadiene rubber, neoprene and the like.
Zinc Borate is an inorganic compound used as a flame retardant and a smoke suppressant.


Zinc borate is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc Borate can be used in the production of paper, textiles, decorative panels, flooring, wallpaper, carpets, ceramic glazes, biocides, paints to improve fireproof performance.


Zinc Borate is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc Borate can replace antimony(III) oxide as a synergist in both halogen-based and halogen-free systems.
Zinc Borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.


In electrical insulator plastics Zinc Borate suppresses arcing and tracking.
In halogen-containing systems, zinc borate is used together with antimony trioxide and alumina trihydrate.
In halogen-free system, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.


During burning the plastics, a porous borate ceramics is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.
Zinc borate is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.


Zinc Borate is also used in some intumescent systems.
Still, Zinc Borate also has many other useful characteristics.
Zinc borate is found in plastics and cellulose fibres, paints and fungicides.


Applications of Zinc Borate: As we mentioned, zinc borate is a versatile compound with many different applications.
Zinc borate is used as flame retardant, corrosion retardant and smoke suppressor in polymers and coatings, especially in pvc, nylon and halogenated polyester.


Zinc Borate is used in the manufacture of high temperature resistant plastics as it has a high dehydration temperature.
Zinc borate has areas of use in in fireproof cables, fireproof fabrics, electrical-electronic components, paints, automobile-
aircraft interior parts, paper and textile industry.


Zinc Borate is often preferred because it is a more effective smoke suppressor when compared to other flame retardants and is cheaper than other flame retardants.
In recent years, the use of zinc borate in combination with other flame retardants in different applications has been increasing.


For example, zinc borate is used in combination with aluminum hydroxyl and magnesium hydroxyl in halogen-containing and non-containing systems.
Zinc borate is also used to reduce melting point in glass and
ceramic industry, as well as to protect wood components as fungus and insecticide in addition to the use of flame retardant.


Due to its flame retardant, smoke suppressing and antibacterial properties and halogen-free properties, Zinc Borate has been the raw material sought in the rubber and plastic industry in recent years.
Zinc Borate works in harmony with other non-flammability chemicals in systems containing and not containing halogen.


Zinc Borate has been used increasingly in conjunction with ATH.
In addition, zinc borate can be used in combination with antimony trioxide or alone.
Zinc borate can be used as a flux in some ceramics.


In electrical insulators Zinc Borate improves the ceramics properties.
Nanopowder zinc borate can be used for the applications above, and also for improving the frictional properties of lubricating oils.
Zinc Borate is used as a fungus and mildew inhibitor, to fire proof textiles, and for other uses.


Zinc Borate has many uses.
The flame-retardant and smoke suppression properties make it ideal for polymers and polyamides.
Zinc Borate also finds use in paper, rubbers and textiles for the same characteristics.


The agricultural industry uses zinc borate as plant nutrition.
Zinc Borate also finds use as a fungicide and to prolong the life of the wood.
Zinc Borate’s beneficial in cables and insulators and as an arc suppressant.


Zinc Borate even finds use in lubricants to improve friction properties.
This versatile mineral, Zinc Borate, has uses in almost every industry.
Zinc borate is prepared as an insoluble double salt from water-soluble zinc and boron compounds.


Compounds having varying amounts of zinc, boron, and water of hydration are available.
The ratio of these components affects the temperature at which the flame-inhibiting powers are activated, as well as the temperature at which they can be processed.


Zinc borates can either be used alone or in combination with other halogen synergists, such as antimony oxide.
In some instances zinc borate is also used with alumina trihydrate to form a glass-like substance that inhibits polymer degradation.
Zinc Borate is used medicine, fireproofing textiles, fungistat and mildew inhibitor, flux in ceramics.


Zinc borate is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc Borate is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc Borate can replace antimony trioxide as a synergist in both halogen-based and halogen-free systems.


Zinc Borate is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc Borate suppresses arcing and tracking.
In halogen-containing systems zinc borate is used together with antimony trioxide and alumina trihydrate.


Zinc Borate catalyzes formation of char and creates a protective layer of glass.
Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.
In halogen-free systems, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.


When burning the plastics, a porous borate ceramic is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.


As the partial, or completely EPA approved substitute for containing halogen and other flame retardants, zinc borate is being directly applied to a wide range of plastics and rubber processing such as PVC, PE, PP, and to enhance polyamide, PVC resin, polyphenylene ethylene, epoxy resin, polyester resin, acid ethylene and natural rubber, styrene butadiene rubber, and chloroprene rubber.


Zinc Borate can also be applied to the production of paper, fiber fabric, decorative panels, floor leather, wallpaper, carpet, ceramic glaze, fungicides, and paint production to improve flame retardant performance.
Zinc borate is used as a corrosion inhibitor, fire retardant, infrared absorber and fungicide in wood preservation.


Zinc Borate can be used in the manufacture of coatings, plastics, coatings, cables, flame retardants and smoke suppressants.
Because it has a low toxicity and it’s not considered hazardous, zinc borate has numerous applications in various industries.
Agriculture: Zinc borate is even used in agriculture both to protect the plant (as a fungicide) and to prolong its life (provides the necessary nutrition.)


Zinc Borate is widely used as a flame retardant and smoke suppressant in the industry for plastic.
Zinc Borate is also used in adhesives, pigments and dyes.
Zinc Borate function as a synergist in plastics and rubber.


Zinc Borate is used as a flame retardant for engineering plastics, rubber items, coatings, textile fabrics, etc.
Zinc borates can be used as multi-functional synergistic additives with other flame retardant additives in polymers to improve the flame retardant performance.


If applied in latex systems that are stable in alkaline environment, the pH of the Zinc Borate dispersion should be adjusted according to the latex- or binder system (with NH3 or MEA or TEA).
Zinc Borate is primarily used as a flame retardant and smoke suppressant in plastics, coatings, rubber and textiles.


Zinc Borate can replace Antimony Trioxide when used with other inorganic flame retardants in both halogen-based and nonhalogenbased systems.
Zinc Borate is used in textiles, paints and pigments.
Zinc Borate is also used in paints, adhesives and pigments.


Zinc Borate is also used as a flame retardant in vinyl chloride latex formulations and as an adhesive in bonding fiberglass insulation to aluminum foil.
Zinc Borate is widely used in applications such as rubber, plastic, wood, cable, and coatings.


Zinc Borate is used as a flame retardant and smoke suppressant for wide range of plastics, rubbers, paper and textiles
Zinc Borate is also used in paints, adhesives, pigments and ceramic industries


-Paints, Pigments And Adhesives uses of Zinc Borate:
The flame-retardant and smoke suppressing properties of zinc borate define how it’s primarily used in paints, adhesives, and pigments.
In combination with zinc phosphate or barium phosphate, Zinc Borate acts as a corrosion inhibiting pigment.


-Polymers uses of Zinc Borate:
*Halogen containing systems: Zinc boride acts as a char promoting agent.
The zinc boride forms a protective layer of glass.
Here, zinc borate works with antimony trioxide and alumina trihydrate.
Zinc borate also has anti-drip properties.


-Halogen-free systems:
Zinc borate works with alumina trihydrate, magnesium hydroxide, red phosphorus or ammonium polyphosphate to do the same.
As the plastics burn, a porous boron ceramic is formed, protecting the layers beneath.
Halogen-free systems show better flame retardant properties.


-Polyamides:
Polyamide plastics have many useful properties.
The heat, smoke and toxic gas from the burning of polyamides hinder their use.
As polyamides consist of strings of polymers, the same flame retardant and smoke suppressant properties apply.

Phosphinate-based and halogen-free electrical insulator plastics use zinc borate.
Alumina trihydrate, magnesium hydroxide and red phosphorus work with zinc borate in these plastics.
The zinc boride acts as a char promoting agent and suppresses afterglow.


-Agriculture uses of Zinc Borate:
The agriculture sector uses zinc borates to increase crop yields and prevent plant diseases.
Some micronutrient formulations also use Zinc Borate in their fertilisers.


-Other Uses of Zinc Borate:
Zinc borate is also used as a flame suppressant in cellulose fibres, paper, rubbers and textiles.
Other uses include a wood treatment for fungus control and to improve the friction properties in lubricants.
Zinc Borate also finds use as an adhesive in bonding aluminium foil and fibreglass.

Zinc Borate even finds use in insulating ceramics as flux.
Zinc Borate also has the effect of reducing firing time and temperatures for ceramics.
For this reason, Zinc Borate’s often used in the manufacture of bricks and porcelain.


-Smoke Suppression
Zinc borate inhibits the formation of smoke by preventing the release of volatile organic compounds during combustion.
By limiting smoke production, zinc borate improves visibility and safety in the event of a fire.


-Industrial uses
zinc borate (2ZnO-3B2Ovl5H2O) has a greater flame retardancy than borates used alone.
Zinc compounds perform most of their flame retardant function in the condensed phase.
Zinc is used with boron in the form of zinc borate, and with molybdenum in the form of zinc molybdate.

Zinc borate can also be used as a flame retardant and smoke suppressant with different polymers. In the case of zinc borate, 2ZnO.3B203.3.5H20, water given off can promote the formation of a cellular char which can act as a good insulator in protecting the underlying polymer or substrate.
Moore studied the effects of zinc borate on smoke reduction and flame retardancy of PVC.

He reported that smoke generation can be suppressed by over 40% by proper combination of additives without an adverse effect on flame retardancy.
The use of zinc borate as a flame retardant and smoke suppressant alone or with other additives, e.g. Sb203, or AI(OH)3, has found wide application in the plastics industry.


-Paints uses of Zinc Borate:
Due to its flame retardant and smoke suppressing properties, zinc borate is widely used in paints and adhesives.
When you combine Zinc Borate with zinc phosphate, for example, it acts as a corrosion inhibiting agent.


-Polyamide Plastics uses of Zinc Borate:
Polyamide plastics, such as nylons, have numerous applications in today’s industries.
But, the toxic smoke and gas released from burning them as well as their heat prevents us from using them to their full potential.

The good news is that flame retardant and smoke suppressant compounds can be used to control this.
To give you a more factual example, both phosphinate-based and halogen-free electrical insulator plastics use zinc borate as it acts as a promoting agent and suppresses the heat and afterglow.


-Polymers uses of Zinc Borate:
In halogen containing systems, zinc acts as a char promoting agent.
As the zinc borate releases its water of hydration, it creates a protective layer, thus minimizing the formation of toxic smoke.

In this case, zinc borate works with antimony trioxide and alumina trihydrate, which also have flame retardant properties.
Zinc borate also has anti-drip properties and suppresses the afterglow.
In halogen free systems, zinc’s properties are enhanced when used with antimony trioxide and alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium.



IN WHICH AREAS IS ZINC BORATE USED?
Certain areas where zinc borate can be used are as follows;
In production of automobile / aircraft interior components, Electrical / electronic parts production , PVC coatings, Fire retardant and fire extinguisher production sectors, In the fungal and insecticide pharmaceutical Industries, At the textile and plastics Institute, and
Cable industry.



COMPOUND TYPE OF ZINC BORATE:
*Household Toxin
*Industrial/Workplace Toxin
*Inorganic Compound
*Synthetic Compound
*Zinc Compound



PRODUCTION METHODS OF ZINC BORATE:
Zinc borate (2ZnO·3B2O3·3.5H2O) in general is produced with the reaction between zinc oxide and boric acid.
Boric acid is solved in water between temperatures 95ºC and 98ºC and zinc oxide and seed crystal of 2ZnO·3B2O3·3.5H2O is added to this solution at a certain stoichiometric ratio.
The reaction continues for a while by mixing and the zinc borate formed is filtered, dried and ground.
The boric acid solution is fed to the system as reflux.



CHEMICAL PROPERTIES OF ZINC BORATE:
Zinc Borate is a white, amorphous powder.
Zinc Borate is soluble in dilute acids; slightly soluble in water.
Zinc Borate is a nonflammable.



CHARACTERISTICS OF ZINC BORATE:
Zinc Borate is a Boron based flame retardant compatible with many polymeric matrices.
Zinc Borate is effective both in the solid phase and in the gas phase and its strong smoke suppressing action, helps to improve time of rescue in case of fire.

Zinc Borate is a multifunctional flame retardant:
promotes the formation of a protective vitreous layer and of a strong char layer, which reduces the formation of toxic and irritant smoke during the fire
Zinc Borate looses its water of hydration at temperatures above 290°C, cooling the front of the flames and subtracting energy to the fire

Zinc Borate acts as a synergist in conjunction with halogenated compounds, so that lower loadings of halogenated flame retardant additives are needed
Zinc Borate shows a strong synergic effect with antimony trioxide; in presence of alumina trihydrate (ATH) the synergic effect is enhanced

Zinc Borate improves resistance against electrical degradation: high anti-arcing and anti-tracking indexes
Zinc Borate is an afterglow suppressant.



WHY ZINC BORATE IS A PREFERRED FIRE REATRDANT ADDITIVE:
Zinc borate is an inorganic compound commonly used as a fire retardant additive due to several advantages over other options.

*Thermal Stability
Unlike ammonium polyphosphate and magnesium hydroxide, zinc borate remains stable at high temperatures without decomposing.
This allows zinc borate to provide fire protection even when a material is exposed to heat over a long duration.

*Halogen-Free
Zinc borate is a halogen-free flame retardant, meaning it does not produce toxic gasses when exposed to fire.
This is an important safety benefit compared to halogenated flame retardants.



SYNERGETICS EFFECT OF ZINC BORATE:
Zinc borate synergizes when combined with other flame retardants like aluminum trihydrate.
Together, these compounds reduce heat release and flame spread more effectively.
This synergistic effect allows lower concentrations of each compound to be used.



VARIANTS OF ZINC BORATE:
Several variants of zinc borate exist, differing by the zinc/boron ratio and the water content:
Zinc borate Firebrake ZB (2ZnO·3 B2O3·3.5H2O), CAS number 138265-88-0
Zinc borate Firebrake 500 (2ZnO·3 B2O3), CAS number 12767-90-7

Zinc borate Firebrake 415 (4ZnO·B2O3·H2O), CAS number 149749-62-2
ZB-467 (4ZnO·6B2O3·7H2O), CAS number 1332-07-6
ZB-223 (2ZnO·2B2O3·3H2O), CAS number 1332-07-6
The hydrated variants lose water between 290–415 °C.



HOW ZINC BORATE WORKS AS A FIRE REATRDENT:
Zinc borate (ZB) is an inorganic compound that acts as a flame retardant by releasing water and forming a protective layer of boron oxide on the surface of combustible materials.

When exposed to heat, Zinc Borate decomposes endothermically, absorbing energy from the surroundings.
This decomposition produces water vapor and boric acid, which then dehydrates to form a molten boron oxide layer.

The water released by Zinc Borate dilutes combustible gasses and lowers the flame’s temperature.
The boron oxide layer acts as a protective barrier, preventing oxygen from reaching the fuel and suppressing smoke emissions.

Zinc Borate can achieve fire retardation independently, but it is often used with ammonium polyphosphate, magnesium hydroxide, and other flame retardant additives to improve performance through a synergistic effect.



PHYSICAL and CHEMICAL PROPERTIES of ZINC BORATE:
Chemical Formula: Zn3B2O6
MDL Number: MFCD00069397
EC No.: 233-803-1
PubChem CID: 167155
IUPAC Name: trizinc; diborate
SMILES: B([O-])([O-])[O-].B([O-])([O-])[O-].[Zn+2].[Zn+2].[Zn+2]
InChI Identifier: InChI=1S/2BO3.3Zn/c22-1(3)4;;;/q2-3;3*+2
InChI Key: BIKXLKXABVUSMH-UHFFFAOYSA-N
CAS Number: 12513-27-8
Assay (purity): 95%
Purity method: by elemental analysis
Molecular weight: 434.69
Form: solid

Appearance: white powder
Melting point: 650°C
Molecular formula: 2ZnO · 3B2O3 · 3.5H2O
Linear formula: 2ZnO · 3B2O3 · 3.5H2O
CBNumber: CB3709911
Molecular Formula: B2O6Zn3
Molecular Weight: 313.79
MOL File: 1332-07-6.mol
Melting point: 980°C
Density: 3.64 g/cm³
LogP: -0.292 (est)
CAS DataBase Reference: 1332-07-6 (CAS DataBase Reference)

EWG's Food Scores: 2-3
FDA UNII: 21LB2V459E
EPA Substance Registry System: Zinc borate (1332-07-6)
Pesticides Freedom of Information Act (FOIA): Zinc Borate
Chemical Formula: BO3Zn
Average Molecular Mass: 124.218 g/mol
Monoisotopic Mass: 122.923 g/mol
CAS Registry Number: 1332-07-6
IUPAC Name: zinc(2+) ion borate
Traditional Name: zinc(2+) ion borate
SMILES: [Zn++].[O-]B([O-])[O-]
InChI Identifier: InChI=1S/BO3.Zn/c2-1(3)4;/q-3;+2

InChI Key: InChIKey=HPMASTSTJMNRGN-UHFFFAOYSA-N
Molecular Weight: 313.8 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0
Exact Mass: 311.77242 g/mol
Monoisotopic Mass: 309.77552 g/mol
Topological Polar Surface Area: 138Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 8
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes
Compound Formula: B2O6Zn3
Molecular Weight: 313.7584 g/mol
Appearance: White solid
Melting Point: 980 °C
Boiling Point: N/A
Density: 3.64 g/cm3
Solubility in H2O: N/A

Exact Mass: 311.772416 g/mol
Monoisotopic Mass: 309.775525 g/mol
CAS Number: 12513-27-8
Assay (purity): 95%
Purity method: by elemental analysis
Molecular weight: 434.69
Form: solid
Appearance: white powder
Melting point: 650C
Molecular formula: 2ZnO · 3B2O3 · 3.5H2O
Linear formula: 2ZnO · 3B2O3 · 3.5H2O
IUPAC Nametrizinc: diborate

Molecular Weight: 313.8g/mol
Molecular Formula: B2O6Zn3
SMILES: B([O-])([O-])[O-].B([O-])([O-])[O-].[Zn+2].[Zn+2].[Zn+2]
InChI: InChI=1S/2BO3.3Zn/c2*2-1(3)4;;;/q2*-3;3*+2
InChIKey: BIKXLKXABVUSMH-UHFFFAOYSA-N
Melting Point: 980°C
Density: 3.64 g/cm³ (20°C)
Solubility: Soluble in dilute acids; slightly soluble in water;0.3% in water at 20 °C
Appearance: White solid
Color/Form: White, amorphous powder;White granular
Complexity: 8

Covalently-Bonded Unit Count: 5
EC Number: 215-566-6;238-763-9
Exact Mass: 311.77242g/mol
Formal Charge: 0
Heavy Atom Count: 11
Monoisotopic Mass: 309.77552g/mol
Odor: None
Molecular Weight: 313.8 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 0

Exact Mass: 311.77242 g/mol
Monoisotopic Mass: 309.77552 g/mol
Topological Polar Surface Area: 138 Ų
Heavy Atom Count: 11
Formal Charge: 0
Complexity: 8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0

Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes
Compound Formula: B2O6Zn3
Molecular Weight: 313.7584 g/mol
Appearance: White solid
Melting Point: 980 °C
Boiling Point: N/A
Density: 3.64 g/cm³
Solubility in H2O: N/A
Exact Mass: 311.772416 g/mol
Monoisotopic Mass: 309.775525 g/mol



FIRST AID MEASURES of ZINC BORATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC BORATE:
-Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC BORATE:
-Extinguishing media:
*Suitable extinguishing media:
Use extinguishing measures that are appropriate to local circumstances and the
surrounding environment.
-Further information:
The product itself does not burn.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC BORATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Choose body protection in relation to its type.
*Respiratory protection:
Respiratory protection is not required.
-Control of environmental exposure:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.



HANDLING and STORAGE of ZINC BORATE:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
*Storage class
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC BORATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


ZINC BORATE FLAME RETARDANT
Zinc borate flame retardant is a halogen-free, inorganic boron based multifunctional flame retardant.
Zinc borate flame retardant is non-toxic, has excellent dispersibility in a number of different polymer systems and shows high thermal stability.
Zinc borate flame retardant is used in paints, adhesives, plastics, cellulose fibres , rubbers and textiles.

CAS: 138265-88-0
MF: B6O11Zn2
MW: 371.64

Synonyms
FIREBRAKE(R) 415;FIREBRAKE(R) 500;FIREBRAKE(R) ZB;BOROGARD(R) ZB;BORON ZINC HYDROXIDE OXIDE;ZINC BORATE EP;Boron zinc hydroxide oxide (B12Zn4(OH)14O15);BORONZINCHYDROXIDEOXIDEAnhydrous;ZINC BORATE;1332-07-6;10361-94-1;trizinc;diborate;Firebrake ZB;21LB2V459E;Diboron zinc tetraoxide;Bonrex FC;zinc(II) borate;Flamtard Z 10;ZT (fire retardant);Alcanex FR 100;Alcanex FRC 600;Climax ZB 467;Firebrake ZB 2335;Borax 2335;ZB 467 Lite;ZINC BORATE [HSDB];UNII-21LB2V459E;ZINC BORATE [WHO-DD];DTXSID6091554;HSDB 1046;FRC 600;XPI 187;SZB 2335;ZSB 2335;EINECS 215-566-6;EINECS 238-763-9;ZB 112;ZB 237;ZN 100;JS 9502;Boric acid (HBO2), zinc salt (2:1);DB-372151;NS00075651;Q27253563

Zinc borate flame retardant is a Boron based flame retardant compatible with manypolymeric matrices.
Zinc borate flame retardant is effective both in the solid phase and in the gas phase andits strong smoke suppressing action, helps to improve time of rescue in case of fire.
Zinc borate flame retardant is a multifunctional flame retardant:

Zinc borate flame retardant is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc borate flame retardant is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc borate flame retardant can replace antimony trioxide as a synergist in both halogen-based and halogen-free systems.
Zinc borate flame retardant is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc borate flame retardant suppresses arcing and tracking.

Zinc borate flame retardant is a non-halogenated flame retardant.
Zinc borate flame retardant is useful as a flame retardant in polyethylene and PVC.
The boron functions as a flame retardant by forming trihalides which are effective Lewis acids.
The boron trihalides promote cross-linking which minimizes flammable gasses forming from the polymer.
In addition to the hydrate, Zinc borate flame retardant can be offered as the metaborate.

In halogen-containing systems, Zinc borate flame retardant is used together with antimony trioxide and alumina trihydrate.
Zinc borate flame retardant catalyzes formation of char and creates a protective layer of glass.
Zinc catalyzes the release of halogens by forming zinc halides and zinc oxyhalides.
In halogen-free system, Zinc borate flame retardant can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.
During burning the plastics, a porous borate ceramics is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.
Zinc borate flame retardant is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.

Zinc borate flame retardant is also used in some intumescent systems.
Zinc borate flame retardant has synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.
Zinc borate flame retardant acts as a broad-spectrum fungicide in plastics and wood products.
Zinc borate flame retardant can be used as a flux in some ceramics.
In electrical insulators Zinc borate flame retardant improves the ceramics properties.
Nanopowder Zinc borate flame retardant can be used for the applications above, and also for improving the frictional properties of lubricating oils.

As a flame retardant, Zinc borate flame retardant loses its water of hydration at temperatures above 290°C, cooling the front of the flames and subtracting energy to the fire and it can replace levels of antimony trioxide as a synergist in both halogen-based and halogen-free systems.
In halogen-containing systems, Zinc borate flame retardant can be used together with antimony trioxide and alumina trihydrate where Zinc borate flame retardant shows a strong synergistic effect.
Here Zinc borate flame retardant catalyses the formation of char and creates a protective layer of glass.
Zinc borate flame retardant also acts as a synergist in conjunction with other halogenated compounds, so that lower loadings of halogenated flame retardant additives are required.

In halogen-free systems, zinc borate can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate.
Additionally Zinc borate flame retardant is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.
Zinc borate flame retardant is also used in some intumescent systems.
Zinc borate flame retardant is an inorganic compound that acts as a flame retardant by releasing water and forming a protective layer of boron oxide on the surface of combustible materials.
When exposed to heat, Zinc borate flame retardant decomposes endothermically, absorbing energy from the surroundings.
This decomposition produces water vapor and boric acid, which then dehydrates to form a molten boron oxide layer.

The water released by Zinc borate flame retardant dilutes combustible gasses and lowers the flame’s temperature.
The boron oxide layer acts as a protective barrier, preventing oxygen from reaching the fuel and suppressing smoke emissions.
Zinc borate flame retardant can achieve fire retardation independently, but it is often used with ammonium polyphosphate, magnesium hydroxide, and other flame retardant additives to improve performance through a synergistic effect.
Zinc borate flame retardant is an inorganic compound, a borate of zinc.
Zinc borate flame retardant is a white crystalline or amorphous powder insoluble in water.
Zinc borate flame retardant's toxicity is low.
Zinc borate flame retardant's melting point is 980 °C.

Uses
Zinc borate flame retardant is primarily used as a flame retardant in plastics and cellulose fibers, paper, rubbers and textiles.
Zinc borate flame retardant is also used in paints, adhesives, and pigments.
As a flame retardant, Zinc borate flame retardant can replace antimony(III) oxide as a synergist in both halogen-based and halogen-free systems.
Zinc borate flame retardant is an anti-dripping and char-promoting agent, and suppresses the afterglow.
In electrical insulator plastics Zinc borate flame retardant suppresses arcing and tracking.

In halogen-containing systems, Zinc borate flame retardant is used together with antimony trioxide and alumina trihydrate.
Zinc borate flame retardant catalyzes formation of char and creates a protective layer of glass.
Zinc borate flame retardant the release of halogens by forming zinc halides and zinc oxyhalides.
In halogen-free system, Zinc borate flame retardant can be used together with alumina trihydrate, magnesium hydroxide, red phosphorus, or ammonium polyphosphate. During burning the plastics, a porous borate ceramics is formed that protects the underlying layers.
In presence of silica, borosilicate glass can be formed at plastic burning temperatures.

Zinc borate flame retardant is used in polyvinyl chloride, polyolefins, polyamides, epoxy resins, polyesters, thermoplastic elastomers, rubbers, etc.
Zinc borate flame retardant is also used in some intumescent systems.
Zinc borate flame retardant has synergistic effect with zinc phosphate or barium borate as a corrosion inhibitor pigment.
Zinc borate flame retardant acts as a broad-spectrum fungicide in plastics and wood products.
Zinc borate flame retardant can be used as a flux in some ceramics.
In electrical insulators Zinc borate flame retardant improves the ceramics properties.
Nanopowder Zinc borate flame retardant can be used for the applications above, and also for improving the frictional properties of lubricating oils.
Zinc borate flame retardant is also used as a corrosion inhibitor in coatings.

Production Methods
Production is through the reaction of zinc oxide with boric acid at 90–100°C.
Thermal stability makes Zinc borate flame retardant attractive as a fire-retardant additive for plastics and rubbers, which require high processing temperatures.
ZINC CARBONATE
ZnCl;TRIS;ZnCl2;Zinco;8VTE 1L;TRISMAT;Zinc chL;zintrace;ai3-04470;Zinctrace CAS No.7646-85-7
ZINC CHLORIDE
Zinc Chloride Zinc chloride is the name of chemical compounds with the formula ZnCl2 and its hydrates. Zinc chlorides, of which nine crystalline forms are known, are colorless or white, and are highly soluble in water. This white salt is hygroscopic and even deliquescent. Samples should therefore be protected from sources of moisture, including the water vapor present in ambient air. Zinc chloride finds wide application in textile processing, metallurgical fluxes, and chemical synthesis. No mineral with this chemical composition is known aside from the very rare mineral simonkolleite, Zn5(OH)8Cl2·H2O. Properties Chemical formula ZnCl2 Molar mass 136.315 g/mol Appearance white crystalline solid hygroscopic and very deliquescent Odor odorless Density 2.907 g/cm3 Melting point 290 °C (554 °F; 563 K)[1] Boiling point 732 °C (1,350 °F; 1,005 K)[1] Solubility in water 432.0 g/ 100 g (25 °C) Solubility soluble in ethanol, glycerol and acetone Solubility in alcohol 430.0 g/100ml Magnetic susceptibility (χ) −65.0·10−6 cm3/mol Hydrates Five hydrates of zinc chloride are known: ZnCl2(H2O)n with n = 1, 1.5, 2.5, 3 and 4.[14] The tetrahydrate ZnCl2(H2O)4 crystallizes from aqueous solutions of zinc chloride. Preparation and purification Anhydrous ZnCl2 can be prepared from zinc and hydrogen chloride: Zn + 2 HCl → ZnCl2 + H2 Hydrated forms and aqueous solutions may be readily prepared similarly by treating Zn metal, zinc carbonate, zinc oxide, and zinc sulfide with hydrochloric acid: ZnS + 2 HCl + 4 H2O → ZnCl2(H2O)4 + H2S Unlike many other elements, zinc essentially exists in only one oxidation state, 2+, which simplifies purification of the chloride. Commercial samples of zinc chloride typically contain water and products from hydrolysis as impurities. Such samples may be purified by recrystallization from hot dioxane. Anhydrous samples can be purified by sublimation in a stream of hydrogen chloride gas, followed by heating the sublimate to 400 °C in a stream of dry nitrogen gas.[15] Finally, the simplest method relies on treating the zinc chloride with thionyl chloride.[16] Reactions Molten anhydrous ZnCl2 at 500–700 °C dissolves zinc metal, and, on rapid cooling of the melt, a yellow diamagnetic glass is formed, which Raman studies indicate contains the Zn2+ 2 ion.[14] A number of salts containing the tetrachlorozincate anion, ZnCl2−4, are known.[10] "Caulton's reagent", V2Cl3(thf)6Zn2Cl6 is an example of a salt containing Zn2Cl2−6. The compound Cs3ZnCl5 contains tetrahedral ZnCl2−4 and Cl− anions. No compounds containing the ZnCl4−6 ion have been characterized. Whilst zinc chloride is very soluble in water, solutions cannot be considered to contain simply solvated Zn2+ ions and Cl− ions, ZnClxH2O(4−x) species are also present. Aqueous solutions of ZnCl2 are acidic: a 6 M aqueous solution has a pH of 1.[14] The acidity of aqueous ZnCl2 solutions relative to solutions of other Zn2+ salts is due to the formation of the tetrahedral chloro aqua complexes where the reduction in coordination number from 6 to 4 further reduces the strength of the O–H bonds in the solvated water molecules.[22] In alkali solution in the presence of OH− ion various zinc hydroxychloride anions are present in solution, e.g. Zn(OH)3Cl2−, Zn(OH)2Cl2−2, ZnOHCl2−3, and Zn5(OH)8Cl2·H2O (simonkolleite) precipitates. When ammonia is bubbled through a solution of zinc chloride, the hydroxide does not precipitate, instead compounds containing complexed ammonia (ammines) are produced, Zn(NH3)4Cl2·H2O and on concentration ZnCl2(NH3)2.[24] The former contains the Zn(NH3)62+ ion,[5] and the latter is molecular with a distorted tetrahedral geometry.[25] The species in aqueous solution have been investigated and show that Zn(NH3)42+ is the main species present with Zn(NH3)3Cl+ also present at lower NH3:Zn ratio. Aqueous zinc chloride reacts with zinc oxide to form an amorphous cement that was first investigated in the 1855 by Stanislas Sorel. Sorel later went on to investigate the related magnesium oxychloride cement, which bears his name. When hydrated zinc chloride is heated, one obtains a residue of Zn(OH)Cl e.g. ZnCl2·2H2O → ZnCl(OH) + HCl + H2O The compound ZnCl2·1⁄2HCl·H2O may be prepared by careful precipitation from a solution of ZnCl2 acidified with HCl. It contains a polymeric anion (Zn2Cl5−)n with balancing monohydrated hydronium ions, H5O2+ ions. The formation of highly reactive anhydrous HCl gas formed when zinc chloride hydrates are heated is the basis of qualitative inorganic spot tests. The use of zinc chloride as a flux, sometimes in a mixture with ammonium chloride (see also Zinc ammonium chloride), involves the production of HCl and its subsequent reaction with surface oxides. Zinc chloride forms two salts with ammonium chloride: (NH4)2ZnCl4 and (NH4)3ClZnCl4, which decompose on heating liberating HCl, just as zinc chloride hydrate does. The action of zinc chloride/ammonium chloride fluxes, for example, in the hot-dip galvanizing process produces H2 gas and ammonia fumes.[31] Cellulose dissolves in aqueous solutions of ZnCl2, and zinc-cellulose complexes have been detected.[32] Cellulose also dissolves in molten ZnCl2 hydrate and carboxylation and acetylation performed on the cellulose polymer.[33] Thus, although many zinc salts have different formulas and different crystal structures, these salts behave very similarly in aqueous solution. For example, solutions prepared from any of the polymorphs of ZnCl2, as well as other halides (bromide, iodide), and the sulfate can often be used interchangeably for the preparation of other zinc compounds. Illustrative is the preparation of zinc carbonate: ZnCl2(aq) + Na2CO3(aq) → ZnCO3(s) + 2 NaCl(aq) Applications As a metallurgical flux Zinc chloride reacts with metal oxides (MO) to give derivatives of the idealized formula MZnOCl2.[34][additional citation(s) needed] This reaction is relevant to the utility of ZnCl2 solution as a flux for soldering — it dissolves passivating oxides, exposing the clean metal surface.[34] Fluxes with ZnCl2 as an active ingredient are sometimes called "tinner's fluid". In organic synthesis Zinc chloride is a useful Lewis acid in organic chemistry.[35] Molten zinc chloride catalyses the conversion of methanol to hexamethylbenzene: 15 CH3OH → C6(CH3)6 + 3 CH4 + 15 H2O Other examples include catalyzing (A) the Fischer indole synthesis,[37] and also (B) Friedel-Crafts acylation reactions involving activated aromatic rings Related to the latter is the classical preparation of the dye fluorescein from phthalic anhydride and resorcinol, which involves a Friedel-Crafts acylation. This transformation has in fact been accomplished using even the hydrated ZnCl2 sample shown in the picture above. The combination of hydrochloric acid and ZnCl2, known as the "Lucas reagent", is effective for the preparation of alkyl chlorides from alcohols. Zinc chloride also activates benzylic and allylic halides towards substitution by weak nucleophiles such as alkenes:[41] In similar fashion, ZnCl2 promotes selective NaBH3CN reduction of tertiary, allylic or benzylic halides to the corresponding hydrocarbons. Zinc chloride is also a useful starting reagent for the synthesis of many organozinc reagents, such as those used in the palladium catalyzed Negishi coupling with aryl halides or vinyl halides.[42] In such cases the organozinc compound is usually prepared by transmetallation from an organolithium or a Grignard reagent, for example: Zinc enolates, prepared from alkali metal enolates and ZnCl2, provide control of stereochemistry in aldol condensation reactions due to chelation on to the zinc. In the example shown below, the threo product was favored over the erythro by a factor of 5:1 when ZnCl2 in DME/ether was used.[43] The chelate is more stable when the bulky phenyl group is pseudo-equatorial rather than pseudo-axial, i.e., threo rather than erythro. In textile and paper processing Concentrated aqueous solutions of zinc chloride (more than 64% weight/weight zinc chloride in water) have dissolving starch, silk, and cellulose. Relevant to its affinity for these materials, ZnCl2 is used as a fireproofing agent and in fabric "refresheners" such as Febreze. Vulcanized fibre is made by soaking paper in concentrated zinc chloride. Smoke grenades The zinc chloride smoke mixture ("HC") used in smoke grenades contains zinc oxide, hexachloroethane and granular aluminium powder, which, when ignited, react to form zinc chloride, carbon and aluminium oxide smoke, an effective smoke screen.[44] Fingerprint detection Ninhydrin reacts with amino acids and amines to form a colored compound "Ruhemann's purple" (RP). Spraying with a zinc chloride solution forms a 1:1 complex RP:ZnCl(H2O)2, which is more readily detected as it fluoresces more intensely than RP.[45] Disinfectant and wood preservative Dilute aqueous zinc chloride was used as a disinfectant under the name "Burnett's Disinfecting Fluid". [46] From 1839 Sir William Burnett promoted its use as a disinfectant as well as a wood preservative.[47] The Royal Navy conducted trials into its use as a disinfectant in the late 1840s, including during the cholera epidemic of 1849; and at the same time experiments were conducted into its preservative properties as applicable to the shipbuilding and railway industries. Burnett had some commercial success with his eponymous fluid. Following his death however, its use was largely superseded by that of carbolic acid and other proprietary products. Skin cancer treatment Zinc chloride has been used in alternative medicine to cause eschars, scabs of dead tissue, in an attempt to cure skin cancers.[48] Various products, such as Cansema or "black salve", containing zinc chloride and sold as cancer cures have been listed by the U.S. Food and Drug Administration (FDA) as fake [49] with warning letters being sent to suppliers.[50] Scarring and skin damage are associated with escharotic substances. Safety Zinc chloride is a chemical irritant of the eyes, skin, and respiratory system. General description Electrodeposition of zinc on glassy carbon and nickel substrates in zinc chloride-1-ethyl-3-methylimidazolium chloride molten salt is studied.[4] Application Zinc Chloride may be used: • as catalyst in knoevenagel condensation of carbonyl substrates with acidic methylene reagents[3] • in the preparation of porous carbon nanofibers, useful in the fabrication of efficient electrodes for supercapacitors[5] • as a catalyst in preparation of poly(propylene fumarate)[6] • in the low temperature synthesis of nanocrystalline zinc oxide films[1] • in the synthesis of zinc oxide nanoparticles with low agglomeration. Aqueous suspensions of the nanoparticles displayed high transmittance in the visible light range, but exhibited strong absorption in the UV range. Zinc Chloride is a chemical compound, which is composed of zinc and chlorine. It is a hygroscopic white crystalline ionic salt with the chemical formula ZnCl2. Zinc Chloride is soluble in mediums such as water, glycerol, ether and alcohol. Since Zinc chloride is a deliquescent, it must be protected from sources of moisture such as water vapor. Synthesis and Purification Anhydrous zinc chloride is synthesized by treating zinc with hydrogen chloride. Zn(s) + 2 HCl → ZnCl2 + H2(g) Whereas, hydrated and aqueous forms of zinc chloride are prepared by treating zinc with hydrochloric acid. Zinc metal could either be in the form of zinc sulfide or zinc oxide. ZnS(s) + 2 HCl(aq) → ZnCl2(aq) + H2S(g) There are impurities present in zinc chloride samples due to hydrolysis. The purification of chloride is simple due to the existence one oxidation state (2+) of zinc. Purification can be done through recrystallization from dioxane (hot). The purification of anhydrous zinc chloride can be done through sublimation with hydrogen chloride gas, followed by the subsequent heating of the sublimate to around 400 °C with dry nitrogen gas. Zinc chloride can also be purified by treating it with thionyl chloride. USES Zinc Chloride has numerous applications in different industries, including pharmaceuticals, health care and paper manufacturing industry. Chemical products are also formulated using zinc chloride. The uses of zinc chloride, based on the type of the industry are as follows: 1. Chemical industry - Zinc chloride is used in the manufacture of various dyes, intermediate chemicals and solvents such as ethyl acetate. 2. Organic product synthesis - Organic products are synthesized in the laboratory for Lewis acid reaction and various other reactions. It also used as a catalyst in organic processes. 3. Metallurgical Industry - It is used a metal etchant and a metallurgical flux. Zinc chloride is used a flux for the soldering process. It is also used in the manufacture of magnesia cement, which is used as an active ingredient for dental fillings and mouthwashes. 4. Printing and Textile industry - Around 64% zinc chloride in water is used to dissolve silk, cellulose and starch. It finds many other applications such as fire proofing agents and fabric refreshers. Vulcanized fibers are manufactured by soaking paper in concentrated zinc chloride. Zinc chloride is used as a mordant in dyeing and printing materials. 5. Petroleum - Zinc chloride is a powerful emulsion breaker, which separates oil from water. 6. Dry cell - Zinc chloride is used in dry cell batteries as an electrolyte. 7. Other Uses - It is used as a condensing agent, dehydrating agent, wood preservative, deodorant and disinfectant. Conclusion Zinc chloride finds numerous applications in various industries, and its scope will increase through research, with the course of time. However, this chemical is known to cause skin irritations, gastrointestinal distress, diarrhea, nausea and pulmonary issues, which can be averted through the adoption of apt safety measures at the chemical manufacturing laboratories and plants. Buy and Sell excess Zinc Chloride online from the best trading portal for the chemical industry. Zinc chloride had the greatest irritancy potential, causing parakeratosis, hyperkeratosis, inflammatory changes in the epidermis and superficial dermis, and acanthosis of the follicular epithelia. Receiving dissolving zinc or its oxide in hydrochloric acid, followed by evaporation of the solution; heating molten zinc in a chlorine stream. Application calico printing; making dental cements; antiseptic impregnation of wood (for example, sleepers); cleaning the surface of metals from oxides before brazing (known as "Soldering acid"); component in the production of fiber; refining of molten zinc alloys; fractional analysis of coal samples; in galvanic cells. Toxicity Zinc chloride is highly toxic and a strong irritant. Causes skin burns. Eye contact is especially dangerous. Zinc Chloride is the name of chemical compounds with the formula ZnCl 2 and its hydrates. Zinc chlorides, of which nine crystalline forms are known, are colorless or white and well soluble in water. ZnCl 2 itself is hygroscopic and even spreads. Therefore, samples must be protected from sources of moisture, including water vapor present in the ambient air. Zinc chloride is widely used in textile processing, metallurgical fluxes, and chemical synthesis. No mineral with such a chemical composition is known, except very rare mineral of simoncolleite Zn 5 (OH) 8 Cl 2 · H 2 O. Zinc chloride is also called zinc chloride and zinc dichloride. Zinc Chloride This chemical reagent has a fairly wide range of applications. Zinc chloride (ZnCl2) is white crystals or flakes, sometimes with a yellowish tinge, capable of absorbing water vapor from the environment. Main characteristics - Complete lack of smell. - Solubility, which differs depending on the temperature of the water. For example, at a temperature of 25 ° C in 100 g of water, you can dissolve 432 g of zinc chloride, and at a temperature of 100 ° C - already 614 g. On average, the compound has 80 percent solubility in water. Along with water, acetone, ethyl alcohol, ether and glycerin are good solvents for zinc chloride. - Not flammable. - It is toxic by inhalation, in contact with the skin and mucous membranes, it causes chemical burns, therefore it is necessary to work with this substance using protective equipment. Production Industrial production of zinc chloride is carried out in two ways. In the first, zinc is dissolved in hydrochloric acid. Moreover, for this method, both pure zinc and its oxides and even zinc-containing secondary raw materials are suitable. After dissolution, the solution is evaporated. The second method involves the use of zinc in liquid or (less often) granular form. Chlorine is fed to the zinc, while the zinc is heated to a temperature of 420 ° C. Zinc chloride is purified by sublimation; production standards are prescribed in GOST 7345-78 and 4529-78. Storage and transportation Zinc dichloride The storage area must be dry and well ventilated. It is important to exclude the possibility of spillage and spillage of the compound (if it is transported in the form of a solution), for which it is recommended to use sealed containers. The shelf life, on average, is from 2 months to six months. Zinc dichloride is transported in accordance with the rules for the carriage of goods that apply to this type of transport. During transportation, the reagent must be hermetically packed, and the container must be marked in accordance with GOST 19433-88. ZnCl2 is transported and stored usually in sealed tanks or barrels. Application Zinc chloride is widely used in completely different fields of industry. The most common areas of its use: - In dentistry for the production of cements. - For printing drawings on calico, in the production of dyes, including for dyes of cotton fabrics, in the light industry. - For the production of refractory impregnations of various materials. - For oil refining. - As a dehumidifier. - In the coal industry - for conducting fractional tests of coal samples. - In woodworking for antiseptic impregnation of wood. - In metallurgy for the refining of melts, for the purification of metals from the oxide layer. - In the manufacture of batteries. In alkali solution in the presence of OH− ion various zinc hydroxychloride anions are present in solution, e.g. Zn(OH)3Cl2−, Zn(OH)2Cl2−2, ZnOHCl2−3, and Zn5(OH)8Cl2·H2O (simonkolleite) precipitates.[22] When ammonia is bubbled through a solution of zinc chloride, the hydroxide does not precipitate, instead compounds containing complexed ammonia (ammines) are produced, Zn(NH3)4Cl2·H2O and on concentration ZnCl2(NH3)2.[23] The former contains the Zn(NH3)62+ ion [4], and the latter is molecular with a distorted tetrahedral geometry.[24] The species in aqueous solution have been investigated and show that Zn(NH3)42+ is the main species present with Zn(NH3)3Cl+ also present at lower NH3:Zn ratio. Aqueous zinc chloride reacts with zinc oxide to form an amorphous cement that was first investigated in the 1855 by Stanislas Sorel. Sorel later went on to investigate the related magnesium oxychloride cement, which bears his name.When hydrated zinc chloride is heated, one obtains a residue of Zn(OH)Cl e.g. ZnCl2·2H2O → ZnCl(OH) + HCl + H2O The compound ZnCl2·1⁄2HCl·H2O may be prepared by careful precipitation from a solution of ZnCl2 acidified with HCl. It contains a polymeric anion (Zn2Cl5−)n with balancing monohydrated hydronium ions, H5O2+ ions.The formation of highly reactive anhydrous HCl gas formed when zinc chloride hydrates are heated is the basis of qualitative inorganic spot tests. The use of zinc chloride as a flux, sometimes in a mixture with ammonium chloride (see also Zinc ammonium chloride), involves the production of HCl and its subsequent reaction with surface oxides. Zinc chloride forms two salts with ammonium chloride: (NH4)2ZnCl4 and (NH4)3ClZnCl4, which decompose on heating liberating HCl, just as zinc chloride hydrate does. The action of zinc chloride/ammonium chloride fluxes, for example, in the hot-dip galvanizing process produces H2 gas and ammonia fumes. Cellulose dissolves in aqueous solutions of ZnCl2, and zinc-cellulose complexes have been detected.Cellulose also dissolves in molten ZnCl2 hydrate and carboxylation and acetylation performed on the cellulose polymer. Thus, although many zinc salts have different formulas and different crystal structures, these salts behave very similarly in aqueous solution. For example, solutions prepared from any of the polymorphs of ZnCl2, as well as other halides (bromide, iodide), and the sulfate can often be used interchangeably for the preparation of other zinc compounds. Illustrative is the preparation of zinc carbonate: ZnCl2(aq) + Na2CO3(aq) → ZnCO3(s) + 2 NaCl(aq) Applications As a metallurgical flux Zinc chloride has the ability to react with metal oxides (MO) to give derivatives of the formula MZnOCl2.[additional citation(s) needed] This reaction is relevant to the utility of ZnCl2 solution as a flux for soldering — it dissolves oxide coatings, exposing the clean metal surface.[33] Fluxes with ZnCl2 as an active ingredient are sometimes called "tinner's fluid". Typically this flux was prepared by dissolving zinc foil in dilute hydrochloric acid until the liquid ceased to evolve hydrogen; for this reason, such flux was once known as "killed spirits". Because of its corrosive nature, this flux is not suitable for situations where any residue cannot be cleaned away, such as electronic work. This property also leads to its use in the manufacture of magnesia cements for dental fillings and certain mouthwashes as an active ingredient. In organic synthesis An early use of zinc chloride (Silzic) was in building carbon skeletons by condensation of methanol molecules. Unsaturated hydrocarbons are the major products, with reaction conditions influencing the distribution of products, though some aromatic compounds were formed.[34] In 1880, it was found that molten zinc chloride catalyses an aromatization reaction generating hexamethylbenzene. At the melting point of ZnCl2 (283 °C), the reaction has a ΔG = −1090 kJ/mol and can be idealised as 15 CH3OH → C6(CH3)6 + 3 CH4 + 15 H2O The discoverers of this reaction rationalized it as involving condensation of methylene units followed by complete Friedel-Crafts methylation of the resulting benzene ring with chloromethane generated in situ.Such an alkylation transformation is an application of zinc chloride's moderate strength as a Lewis acid, which is its principal role in laboratory synthesis. Other examples include catalyzing (A) the Fischer indole synthesis,and also (B) Friedel-Crafts acylation reactions involving activated aromatic rings. Related to the latter is the classical preparation of the dye fluorescein from phthalic anhydride and resorcinol, which involves a Friedel-Crafts acylation. This transformation has in fact been accomplished using even the hydrated ZnCl2 sample shown. Hydrochloric acid alone reacts poorly with primary alcohols and secondary alcohols, but a combination of HCl with ZnCl2 (known together as the "Lucas reagent") is effective for the preparation of alkyl chlorides. Typical reactions are conducted at 130 °C. This reaction probably proceeds via an SN2 mechanism with primary alcohols but SN1 pathway with secondary alcohols. Zinc chloride also activates benzylic and allylic halides towards substitution by weak nucleophiles such as alkenes:In similar fashion, ZnCl2 promotes selective NaBH3CN reduction of tertiary, allylic or benzylic halides to the corresponding hydrocarbons. Zinc chloride is also a useful starting reagent for the synthesis of many organozinc reagents, such as those used in the palladium catalyzed Negishi coupling with aryl halides or vinyl halides.In such cases the organozinc compound is usually prepared by transmetallation from an organolithium or a Grignard reagent, for example:Zinc enolates, prepared from alkali metal enolates and ZnCl2, provide control of stereochemistry in aldol condensation reactions due to chelation on to the zinc. In the example shown below, the threo product was favored over the erythro by a factor of 5:1 when ZnCl2 in DME/ether was used.The chelate is more stable when the bulky phenyl group is pseudo-equatorial rather than pseudo-axial, i.e., threo rather than erythro. In textile and paper processing Concentrated aqueous solutions of zinc chloride (more than 64% weight/weight zinc chloride in water) have the interesting property of dissolving starch, silk, and cellulose. Thus, such solutions cannot be filtered through standard filter papers. Relevant to its affinity for these materials, ZnCl2 is used as a fireproofing agent and in fabric "refresheners" such as Febreze. Vulcanized fibre is made by soaking paper in concentrated zinc chloride. Smoke grenades The zinc chloride smoke mixture ("HC") used in smoke grenades contains zinc oxide, hexachloroethane and granular aluminium powder, which, when ignited, react to form zinc chloride, carbon and aluminium oxide smoke, an effective smoke screen. Fingerprint detection Ninhydrin reacts with amino acids and amines to form a colored compound "Ruhemann's purple" (RP). Spraying with a zinc chloride solution forms a 1:1 complex RP:ZnCl(H2O)2, which is more readily detected as it fluoresces better than Ruhemann's purple. Disinfectant Historically, a dilute aqueous solution of zinc chloride was used as a disinfectant under the name "Burnett's Disinfecting Fluid". [45] It is also used in some commercial brands of antiseptic mouthwash. Skin cancer treatment Zinc chloride has been used in alternative medicine to cause eschars, scabs of dead tissue, in an attempt to cure skin cancers.[46] Various products, such as Cansema or "black salve", containing zinc chloride and sold as cancer cures have been listed by the U.S. Food and Drug Administration (FDA) as fake [47] with warning letters being sent to suppliers. Numerous reports in medical literature describe serious scarring and damage to normal skin by escharotic substances. Given these side-effects, its use in treatment is not warranted as there are much safer and more effective alternatives, such as radiation therapy and Mohs surgery.[49][50] Safety Zinc chloride is a skin irritant. After contact of the skin, immediate removal is necessary using soap and plenty of water. After contact of the eyes, adequate measures are rinsing with plenty of water or other eye rinse and contacting an ophthalmologist as soon as possible.[51] Zinc chloride is caustic to the gastrointestinal tract, occasionally leading to hematemesis. Symptoms of acute intoxication are gastrointestinal distress, diarrhea, nausea, and abdominal pain. Vomiting occurs almost universally. The lethal dose in humans is 3–5 g.[citation needed] Decontamination of the gastrointestinal tract after oral uptake of zinc compounds is mostly unnecessary, since patients usually vomit sufficiently. Milk may be administered to decrease absorption of the metal. Zinc levels may be normalized with EDTA salts.[51] Zinc chloride is extremely detrimental to the lungs, and pulmonary exposure to zinc chloride smoke has previously resulted in fatalities.Inhalation of fumes of zinc, zinc oxide, or zinc chloride leads to pulmonary edema and metal fume fever. Onset occurs within 4–6 h and may be delayed up to 8 h. Symptoms include rapid breathing, dyspnea, cough, fever, shivering, sweating, chest and leg pain, myalgias, fatigue, metallic taste, salivation, thirst, and leukocytosis, which can last from 24 to 48 h. In cases of fume inhalation, cortisone preparations should be applied immediately (e.g., by inhalation of Auxiloson) to avoid development of lung edema. Compounds In chemical compounds, zinc exhibits almost exclusively a +2 oxidation state. A few compounds of zinc in the +1 state have been reported, but never any compounds of zinc in the +3 state or higher. Zinc chloride is a chemical compound whose formula is ZnCl2, with a molecular weight of 136.3 g / mol. This product is hygroscopic and deliquescent and therefore must be protected from moisture, even that contained in the atmosphere. Applications: One of the main applications of zinc chloride is to act as an electrolyte in dry batteries (zinc-carbon). Zinc chloride has the ability to attack the metal oxides, this property allowing its use as flux in the weld metal, dissolving the oxide layers, and leaving the metal surface clean. Zinc chloride is used in various fields such as water treatment, as a fireproofing agent in textile processing and in the manufacture of bactericides, fungicides and stabilizers for plastics. USES Dry Cell or Batteries: Zinc Chloride is commonly used in dry cell batteries as an electrolyte where it also acts as a moisture absorbent and corrosion inhibitor. ZnCl2 is an excellent water soluble Zinc source for uses compatible with chlorides. Chloride compounds can conduct electricity when fused or dissolved in water. Chloride materials can be decomposed by electrolysis to chlorine gas and the metal. They are formed through various chlorination processes whereby at least one chlorine anion (Cl-) is covalently bonded to the relevant metal or cation. the item is generally immediately available in most volumes and high purity. A zinc chloride battery is a heavy duty variation of a zinc carbon battery. It is used in applications that require moderate to heavy current drains. Zinc chloride batteries have better voltage discharge per time characteristics and better low temperature performance than carbon zinc batteries. They batteries are used in radios, flashlights, lanterns, fluorescent lanterns, motor driven devices, portable audio equipments, communications equipments, electronic games, calculators, and remote control transmitters. Electroplating : Today, there are three primary types of acid zinc plating baths: straight ammonium chloride, straight potassium chloride and mixed ammonium chloride/potassium chloride. Acid zinc plating systems have several advantages over alkaline cyanide and alkaline non-cyanide zinc plating systems except that in acid zinc plating, the electrolyte is extremely corrosive. Ammonium chloride zinc plating. The ammonium chloride bath is the most forgiving of the three major types of acid zinc plating because of its wide operating parameters. The primary drawback of this system is the high level of ammonia, which can cause problems in wastewater treatment. Ammonia acts as a chelator, and if the rinse waters are not segregated from other waste streams, removal of metals to acceptable levels using standard water treatment practices can be difficult and expensive. Ammonia is also regulated in many communities. Potassium chloride zinc plating. Potassium chloride zinc plating solutions are attractive because they contain no ammonia. The disadvantages of this system are a greater tendency to burn on extreme edges and higher operating costs. The potassium bath also requires the use of relatively expensive boric acid to buffer the solution and prevent burning in the high-current-density areas, functions performed by the ammonium chloride in the other systems. Mixed ammonium chloride/potassium chloride zinc plating. This bath combines the best of the ammonia and ammonia-free baths. Because potassium chloride is less expensive than ammonium chloride, the maintenance costs of the mixed bath are lower than the ammonia bath, and it does not require boric acid. The ammonia levels in the rinse waters are low enough that it does not significantly interfere with wastewater treatment, even if plating nickel and copper in the same plant with mixed waste streams. If local regulations restrict the level of ammonia discharged, special waste treatment equipment will be required, and the non-ammonia bath is most likely the best choice. Galvanizing, Soldering and Tinning Fluxes: Zinc Chloride is used in fluxes for galvanizing, soldering and tinning. Its ability to remove oxides and salts from metal surfaces insures good metal to metal bonding. It has the ability to attack metal oxides (MO) to give derivatives of the formula MZnOCl2. This reaction is relevant to the utility of ZnCl2 as a flux for soldering - it dissolves oxide coatings exposing the clean metal
ZINC CHLORIDE ( Chlorure de zinc)
Dichlorozinc 60% ; Zinc dichloride cas no:7646-85-7
ZINC CHLORIDE SOLUTION 60%
Zinc bis[O,O-dioctyl dithiophosphate]; zinc bis(O,O-dioctyl) bis(dithiophosphate); Bis(dithiophosphoric acid O,O-dioctyl)zinc salt; Zinc, bis(O,O-dioctyl phosphorodithioato-S,S')-, (T-4)- CAS NO:7059-16-7
ZINC CITRATE
ZINC CITRATE PREMIUM FORMULA - Our Zinc citrate Tablets are the made with high quality Zinc Citrate 3rd Part Lab Tested - Our All Best Naturals Products come with 3rd Party Independent Lab Tested Zinc citrate Supplement supports healthy immune function & Supports Enzyme Functions No Artificial Color, Flavor or Sweetener, No Preservatives, No Sugar, No Starch, No Corn, No Soy, No Egg, No Lactose, No Gluten, No Wheat, No Yeast, No Fish TOP QUALITY GMP CERTIFIED PRODUCTS - All Best Naturals products are manufactured in accordance with Good Manufacturing Practices (GMP), among the highest standards in the world -- Proudly Made in USA -- Purity & Potency. Brand Solgar Ingredients Zinc citrate (as zinc citrate) Amt Per Serving:30 mg % Daily Value :200%,,Other Ingredients: Microcrystalline cellulose, vegetable cellulose, vegetable magnesium stearate, vegetable stearic acid. Serving Description 1 Vegetable Capsule Diet Type Gluten Free, Kosher, Vegan Material type free GMO Free, Gluten Free About this item Optimal Absorption; Solgar Zinc Citrate contains the citrate form of Zinc citrate to help promote optimal absorption; The 30 mg of Zinc citrate in this formulation represents 273% of the recommended daily value Immune Support; Zinc citrate exerts antioxidant activity and can support a healthy immune system; It also supports cell growth and DNA formation, as well as normal taste and vision Collagen Support; Zinc citrate contributes to healthy skin, nails, and hair; It plays a role in the synthesis of collagen in bone tissue Non GMO, Gluten Free, And Kosher; Solgar Zinc Citrate Vegetable Capsules are suitable for vegans; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and sweetener The Gold Standard: For over 70 years Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials What Are Zinc citrate Supplements Good For? Benefits and More Types Benefits Dosage Safety & Side Effects Bottom Line If you buy something through a link on this page, we may earn a small commission. How this works. Zinc citrate is an essential micronutrient that is crucial to almost every aspect of your health. It’s second only to iron as the most abundant trace mineral in your body (1Trusted Source). Available in many different forms, Zinc citrate supplements are often used to treat an array of ailments. Research shows that this mineral may enhance immune function, stabilize blood sugar levels, and help keep your skin, eyes, and heart healthy. This article reviews the types, benefits, dosage recommendations, and potential side effects of Zinc citrate supplements. Types of Zinc citrate Supplements When choosing a Zinc citrate supplement, you’ll likely notice that there are many different types available. These various forms of Zinc citrate impact health in distinct ways. Here are a few you might find on the market: Zinc citrate gluconate: As one of the most common over-the-counter forms of Zinc citrate, Zinc citrate gluconate is often used in cold remedies, such as lozenges and nasal sprays (2). Zinc citrate acetate: Like Zinc citrate gluconate, Zinc citrate acetate is often added to cold lozenges to reduce symptoms and speed up the rate of recovery (3Trusted Source). Zinc citrate sulfate: In addition to helping prevent Zinc citrate deficiency, Zinc citrate sulfate has been shown to reduce the severity of acne (4Trusted Source). Zinc citrate picolinate: Some research suggests that your body may absorb this form better than other types of Zinc citrate, including Zinc citrate gluconate and zinc citrate (5Trusted Source). Zinc citrate orotate: This form is bound to orotic acid and one of the most common types of Zinc citrate supplements on the market (6). Zinc citrate: One study showed that this type of Zinc citrate supplement is as well-absorbed as Zinc citrate gluconate but has a less bitter, more appealing taste (7Trusted Source). Because it’s one of the most widely available and cost-effective forms of Zinc citrate, Zinc citrate gluconate can be a good option to help bump up your intake without breaking your bank. However, if you’re able to invest a bit more, Zinc citrate picolinate may be better absorbed. Available in capsule, tablet, and lozenge form, there are plenty of options to get your daily dose of Zinc citrate — regardless of the type you choose. However, keep in mind that nasal sprays containing Zinc citrate have been linked to loss of smell and should be avoided (8Trusted Source, 9Trusted Source). SUMMARY There are several forms of Zinc citrate supplements that impact your health in unique ways. They’re generally available in capsule, tablet, and lozenge form. Zinc citrate -containing nasal sprays should be avoided. Potential Benefits Zinc citrate is vital for many aspects of health and has been associated with a variety of benefits. May Improve Immune Function Many over-the-counter medications and natural remedies feature Zinc citrate due to its ability to boost immune function and fight inflammation. One review of seven studies showed that Zinc citrate lozenges containing 80-92 mg of Zinc citrate may reduce common cold duration by up to 33% (10Trusted Source). Zinc citrate may also act as an antioxidant, helping reduce inflammation and protecting against chronic conditions, such as heart disease, cancer, and diabetes (11Trusted Source, 12Trusted Source). One study in 50 older adults found that taking 45 mg of Zinc citrate gluconate for one year decreased several markers of inflammation and reduced the frequency of infections (13Trusted Source). May Promote Blood Sugar Control Zinc citrate is well known for its role in blood sugar control and insulin secretion. Insulin is the hormone responsible for transporting sugar from your bloodstream to your tissues (14Trusted Source). Some research suggests that Zinc citrate may help keep blood sugar levels steady and improve your body’s sensitivity to insulin. One review reported that Zinc citrate supplements were effective at enhancing both short-term and long-term blood sugar control in people with diabetes (15Trusted Source). Other research shows that Zinc citrate may help reduce insulin resistance, which can improve your body’s ability to use insulin efficiently to maintain normal blood sugar levels (16Trusted Source, 17Trusted Source). Helps Fight Acne Zinc citrate supplements are often used to promote skin health and treat common skin conditions like acne (18Trusted Source). Zinc citrate sulfate has been shown to be especially useful for decreasing symptoms of severe acne (4Trusted Source). A 3-month study in 332 people found that taking 30 mg of elemental Zinc citrate — a term that refers to the actual amount of Zinc citrate found in a supplement — was effective at treating inflammatory acne (19Trusted Source). Zinc citrate supplements are also often favored over other treatment methods as they’re inexpensive, effective, and associated with far fewer side effects (18Trusted Source). May Improve Heart Health Heart disease is a serious problem, accounting for roughly 33% of deaths worldwide (20Trusted Source). Some research shows that taking Zinc citrate may improve several risk factors for heart disease and may even lower triglyceride and cholesterol levels. A review of 24 studies found that Zinc citrate supplements helped decrease levels of total and “bad” LDL cholesterol, as well as blood triglycerides, which could potentially aid in preventing heart disease (21Trusted Source). Additionally, one study in 40 young women showed that higher intakes of Zinc citrate were linked to lower levels of systolic blood pressure (the top number of a reading) (22Trusted Source). However, research evaluating the effects of supplements on blood pressure is limited (22Trusted Source). Other research suggests that low levels of serum Zinc citrate may be associated with a higher risk of coronary heart disease, but findings remain inconclusive (23Trusted Source). Slows Macular Degeneration Macular degeneration is a common eye disease and one of the leading causes of vision loss around the globe (24Trusted Source). Zinc citrate supplements are often used to slow the progression of age-related macular degeneration (AMD) and help protect against vision loss and blindness. One study in 72 people with AMD showed that taking 50 mg of Zinc citrate sulfate daily for three months slowed the progression of the disease (25Trusted Source). Similarly, another review of 10 studies reported that supplementing with Zinc citrate was effective at reducing the risk of progression to advanced macular degeneration (26Trusted Source). However, other studies in the review suggested that Zinc citrate supplements alone may not produce significant vision improvements and should be paired with other treatment options to maximize results (26Trusted Source). SUMMARY Zinc citrate may reduce the duration of cold symptoms, support blood sugar control, improve severe and inflammatory acne, decrease heart disease risk, and slow the progression of macular degeneration. Weight management options have evolved Take our quiz to learn more about techniques and tips that will help you achieve your goals. Dosage How much Zinc citrate you should take per day depends on the type, as each supplement contains a different amount of elemental Zinc citrate. For example, Zinc citrate sulfate consists of about 23% elemental Zinc citrate, so 220 mg of Zinc citrate sulfate would equate to about 50 mg of Zinc citrate (27). This amount is usually listed on the label of your supplement, making it easy to determine how much you should take to meet your daily needs. For adults, the recommended daily dosage is typically 15–30 mg of elemental Zinc citrate (4Trusted Source, 28Trusted Source). Higher doses have been used for treating certain conditions, including acne, diarrhea, and respiratory infections. However, due to the potential side effects associated with excess Zinc citrate consumption, it’s best not to exceed the upper limit of 40 mg per day — unless under medical supervision (27). SUMMARY Different Zinc citrate supplements contain varying concentrations of elemental Zinc citrate. The recommended dosage for daily supplements is 15–30 mg. Safety and Side Effects When used as directed, Zinc citrate supplements can be a safe and effective way to increase your Zinc citrate intake and improve several aspects of your health. However, they have been associated with adverse side effects, including nausea, vomiting, diarrhea, and stomach pain (29, 30Trusted Source). Exceeding 40 mg per day of elemental Zinc citrate can cause flu-like symptoms, such as fever, coughing, headache, and fatigue (31Trusted Source). Zinc citrate can also interfere with your body’s ability to absorb copper, potentially leading to a deficiency in this key mineral over time (32Trusted Source). Furthermore, Zinc citrate supplements have been shown to interfere with the absorption of certain antibiotics, reducing their effectiveness if taken at the same time (27). To reduce your risk of side effects, stick to the recommended dosage and avoid exceeding the tolerable upper limit of 40 mg per day — unless under medical supervision. If you experience any negative side effects after taking Zinc citrate supplements, decrease your dosage and consider consulting with your healthcare professional if symptoms persist. SUMMARY Zinc citrate can cause negative side effects, including digestive issues and flu-like symptoms. It may also interfere with the absorption of copper and reduce the effectiveness of certain antibiotics. Zinc citrate is a mineral essential to many aspects of health. Supplementing with 15–30 mg of elemental Zinc citrate daily may improve immunity, blood sugar levels, and eye, heart, and skin health. Be sure not to exceed the upper limit of 40 mg. Zinc citrate’s side effects include digestive issues, flu-like symptoms, and reduced copper absorption and antibiotic effectiveness. Zinc citrate supplements are widely available online, at your local health store, or pharmacy. Plus, if you want to try and increase your Zinc citrate intake through your diet, many foods are rich in this mineral, such as nuts, seeds, legumes, meat, seafood, and dairy. ZINC CITRATE 30 MG VEGETABLE CAPSULES WRITE A REVIEW Zinc citrate promotes healthy skin, supports normal taste and vision, and promotes the synthesis of collagen in bone tissue.* It also supports cell growth and DNA formation.* It exerts antioxidant activity and can support a healthy immune system.* The citrate form of Zinc citrate in this formulation helps to promote optimal absorption.* Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Although the mechanism of action is not completely known, Zinc citrate supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV). Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration. Zinc citrate trihydrate Drug Entry Zinc citrate Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration The water-soluble Zinc citrate salts gluconate, sulfate, and acetate are commonly used as supplements in tablet or syrup form to prevent Zinc citrate deficiency and to treat diarrhea in children in combination with oral rehydration. Zinc citrate is an alternative compound with high Zinc citrate content, slightly soluble in water, which has better sensory properties in syrups but no absorption data in humans. We used the double-isotope tracer method with 67Zn and 70Zn to measure Zinc citrate absorption from zinc citrate given as supplements containing 10 mg of Zinc citrate to 15 healthy adults without food and compared absorption with that from Zinc citrate gluconate and Zinc citrate oxide (insoluble in water) using a randomized, double-masked, 3-way crossover design. Median (IQR) fractional absorption of Zinc citrate from zinc citrate was 61.3% (56.6–71.0) and was not different from that from Zinc citrate gluconate with 60.9% (50.6–71.7). Absorption from Zinc citrate oxide at 49.9% (40.9–57.7) was significantly lower than from both other supplements (P < 0.01). Three participants had little or no absorption from Zinc citrate oxide. We conclude that zinc citrate, given as a supplement without food, is as well absorbed by healthy adults as Zinc citrate gluconate and may thus be a useful alternative for preventing Zinc citrate deficiency and treating diarrhea. The more insoluble Zinc citrate oxide is less well absorbed when given as a supplement without food and may be minimally absorbed by some individuals. This trial was registered at clinicaltrials.gov as NCT01576627. Go to: Introduction Zinc citrate is an essential trace element that has a critical role in maintaining structural and catalytic functions of >200 enzymes involved in major metabolic pathways, including nucleic acid metabolism, protein synthesis, and cell division (1). Although it remains difficult to define Zinc citrate status, Zinc citrate deficiency appears to be common among children in many developing countries, negatively affecting physical growth, immune competence, neural development, and reproductive outcomes, and increasing morbidity and mortality (2). The WHO considers Zinc citrate deficiency to be a major contributor to the burden of disease in developing countries, especially in those with a high mortality rate (3). Several factors contribute to the development of Zinc citrate deficiency, including increased requirements at certain stages of the life cycle, malabsorption, impaired utilization, and increased losses attributable to repeated diarrhea. However, most often the primary cause of Zinc citrate deficiency is inadequate dietary Zinc citrate intake and low bioavailability of Zinc citrate attributable to the consumption of plant-based diets that are high in phytic acid, thus inhibiting Zinc citrate absorption (2). Zinc citrate is lost in greater quantities during diarrhea, and Zinc citrate supplements have been successfully used to treat diarrhea (4). WHO guidelines for the treatment of diarrhea recommend Zinc citrate supplementation in combination with oral rehydration salts solution (5). The WHO recommends the use of the water-soluble compounds Zinc citrate sulfate (23% Zinc citrate), Zinc citrate acetate (30% Zinc citrate), or Zinc citrate gluconate (14% Zinc citrate) in the form of syrups or dispersible tablets for diarrhea management in infants (6). However, Zinc citrate sulfate and Zinc citrate acetate have a strong metallic, bitter, and astringent taste that needs to be masked. Moreover, the low Zinc citrate content of Zinc citrate gluconate makes this compound more expensive. Of the Zinc citrate compounds permitted in the European Union for use as supplements or for food fortification, Zinc citrate sulfate (water soluble, Zinc citrate content of 23%) and Zinc citrate oxide (water insoluble, Zinc citrate content of 80%) are the least expensive and most commonly used (2). An alternative Zinc citrate compound with promising sensory properties is Zinc citrate citrate (Markus Gerhart, Jungbunzlauer Ladenburg, Ladenburg, Germany, personal communication). This compound has a high Zinc citrate content of 31%, is slightly soluble in water, is odorless, and has a relatively low cost (2). However, there are no human absorption data to support the use of zinc citrate. Zinc citrate promotes healthy skin, supports normal taste and vision, and promotes the synthesis of collagen in bone tissue.* It also supports cell growth and DNA formation.* It exerts antioxidant activity and can support a healthy immune system.* The citrate form of Zinc citrate in this formulation helps to promote optimal absorption.* Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Zinc Citrate is a nutritional supplement containing the Zinc citrate salt form of citric acid for the purpose of providing Zinc citrate. As an essential trace element, Zinc citrate is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system. Although the mechanism of action is not completely known, Zinc citrate supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV). Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration. Zinc citrate trihydrate Drug Entry Zinc citrate Zinc citrate is a Zinc citrate salt of citric acid. It is available as dietary supplements as a treatment of Zinc citrate deficiency and source of Zinc citrate, which is an essential trace element. Zinc citrate demonstrates effective absorption following oral administration The water-soluble Zinc citrate salts gluconate, sulfate, and acetate are commonly used as supplements in tablet or syrup form to prevent Zinc citrate deficiency and to treat diarrhea in children in combination with oral rehydration. Zinc citrate is an alternative compound with high Zinc citrate content, slightly soluble in water, which has better sensory properties in syrups but no absorption data in humans. We used the double-isotope tracer method with 67Zn and 70Zn to measure Zinc citrate absorption from zinc citrate given as supplements containing 10 mg of Zinc citrate to 15 healthy adults without food and compared absorption with that from Zinc citrate gluconate and Zinc citrate oxide (insoluble in water) using a randomized, double-masked, 3-way crossover design. Median (IQR) fractional absorption of Zinc citrate from zinc citrate was 61.3% (56.6–71.0) and was not different from that from Zinc citrate gluconate with 60.9% (50.6–71.7). Absorption from Zinc citrate oxide at 49.9% (40.9–57.7) was significantly lower than from both other supplements (P < 0.01). Three participants had little or no absorption from Zinc citrate oxide. We conclude that zinc citrate, given as a supplement without food, is as well absorbed by healthy adults as Zinc citrate gluconate and may thus be a useful alternative for preventing Zinc citrate deficiency and treating diarrhea. The more insoluble Zinc citrate oxide is less well absorbed when given as a supplement without food and may be minimally absorbed by some individuals. This trial was registered at clinicaltrials.gov as NCT01576627. Go to: Introduction Zinc citrate is an essential trace element that has a critical role in maintaining structural and catalytic functions of >200 enzymes involved in major metabolic pathways, including nucleic acid metabolism, protein synthesis, and cell division (1). Although it remains difficult to define Zinc citrate status, Zinc citrate deficiency appears to be common among children in many developing countries, negatively affecting physical growth, immune competence, neural development, and reproductive outcomes, and increasing morbidity and mortality (2). The WHO considers Zinc citrate deficiency to be a major contributor to the burden of disease in developing countries, especially in those with a high mortality rate (3). Several factors contribute to the development of Zinc citrate deficiency, including increased requirements at certain stages of the life cycle, malabsorption, impaired utilization, and increased losses attributable to repeated diarrhea. However, most often the primary cause of Zinc citrate deficiency is inadequate dietary Zinc citrate intake and low bioavailability of Zinc citrate attributable to the consumption of plant-based diets that are high in phytic acid, thus inhibiting Zinc citrate absorption (2). Zinc citrate is lost in greater quantities during diarrhea, and Zinc citrate supplements have been successfully used to treat diarrhea (4). WHO guidelines for the treatment of diarrhea recommend Zinc citrate supplementation in combination with oral rehydration salts solution (5). The WHO recommends the use of the water-soluble compounds Zinc citrate sulfate (23% Zinc citrate), Zinc citrate acetate (30% Zinc citrate), or Zinc citrate gluconate (14% Zinc citrate) in the form of syrups or dispersible tablets for diarrhea management in infants (6). However, Zinc citrate sulfate and Zinc citrate acetate have a strong metallic, bitter, and astringent taste that needs to be masked. Moreover, the low Zinc citrate content of Zinc citrate gluconate makes this compound more expensive. Of the Zinc citrate compounds permitted in the European Union for use as supplements or for food fortification, Zinc citrate sulfate (water soluble, Zinc citrate content of 23%) and Zinc citrate oxide (water insoluble, Zinc citrate content of 80%) are the least expensive and most commonly used (2). An alternative Zinc citrate compound with promising sensory properties is Zinc citrate citrate (Markus Gerhart, Jungbunzlauer Ladenburg, Ladenburg, Germany, personal communication). This compound has a high Zinc citrate content of 31%, is slightly soluble in water, is odorless, and has a relatively low cost (2). However, there are no human absorption data to support the use of zinc citrate.
ZINC DIBENZYL DITHIOCARBAMATE (ZBED)

Zinc Dibenzyl Dithiocarbamate (ZBED) is a chemical compound with the molecular formula C30H32N2S4Zn.
Recognized by its CAS number 14726-36-4, ZBED is commonly used in rubber processing.
Zinc Dibenzyl Dithiocarbamate (ZBED) has a melting point in the range of 183-188 °C, ensuring stability under elevated temperatures.
With a molecular weight of 614.22 g/mol, ZBED serves as an effective vulcanization accelerator in the rubber industry.

CAS Number: 14726-36-4
EC Number: 238-778-0



APPLICATIONS


Zinc Dibenzyl Dithiocarbamate (ZBED) is commonly used as a vulcanization accelerator in the rubber industry.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a crucial role in the processing of rubber compounds for various applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the production of tires, contributing to their strength and durability.

Zinc Dibenzyl Dithiocarbamate (ZBED) serves as a key ingredient in the formulation of rubber sheets for industrial applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the extrusion process to manufacture rubber profiles, seals, and gaskets.
In latex manufacturing, ZBED acts as a primary accelerator, facilitating the vulcanization of latex products.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the production of rubber hoses, ensuring their resistance to wear and aging.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized conveyor belts, contributing to their robustness.

Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the formulation of rubber compounds for sheeting, providing enhanced properties.
Zinc Dibenzyl Dithiocarbamate (ZBED) is an accelerator in the production of rubberized footwear, ensuring durability and wear resistance.

Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the manufacturing of rubber seals and gaskets for automotive applications.
In the production of industrial rubber components, ZBED enhances resistance to environmental factors.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the synthesis of rubberized rollers for use in printing and processing machinery.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the creation of rubberized components for water treatment and wastewater systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the construction industry, including seals.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the formulation of rubberized diaphragms for pumps and valves.
Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the production of rubberized components for electrical cable insulation.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the formulation of rubberized coatings for corrosion protection in various applications.

Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the production of rubberized components for anti-vibration mounts in machinery.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the fabrication of rubberized components for marine applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized components for agricultural machinery.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for medical devices, ensuring compliance with safety standards.

Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the manufacturing of rubberized components for sporting goods, such as balls and athletic equipment.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the formulation of rubberized products for the aerospace industry, including seals and gaskets.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the creation of rubberized components for the production of conveyor belts in material handling systems.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the production of rubberized components for automotive applications, including engine mounts and suspension parts.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the manufacturing of rubberized components for escalator and elevator systems, ensuring smooth operation.

Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized wheels and casters used in material handling equipment.
In the field of renewable energy, ZBED is used in the fabrication of rubberized components for solar panel installations.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the formulation of rubberized components for air handling systems, including HVAC duct connectors.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the production of rubberized components for oil and gas industry applications, such as seals and gaskets.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the creation of rubberized components for the railway industry, including track pads and seals.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the defense sector, including protective gear and equipment.

In the realm of water infrastructure, ZBED is used in the formulation of rubberized components for water treatment plants.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the production of rubberized components for marine fender systems, providing impact resistance at ports.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the formulation of rubberized components for medical devices, ensuring biocompatibility and safety.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the aerospace industry, including seals and gaskets for aircraft.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the creation of rubberized components for sports equipment, such as bicycle tires and golf grips.

Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the formulation of rubberized components for the construction of inflatable structures.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the production of rubberized components for amusement park rides, ensuring safety and reliability.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the formulation of rubberized components for military applications, such as vehicle tracks and equipment.

Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the mining industry, including conveyor belts and seals.
In the realm of agriculture, ZBED is employed in the fabrication of rubberized components for machinery such as combines and tractors.

Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the creation of rubberized components for the production of conveyor belts in material handling systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the formulation of rubberized components for footwear, ensuring comfort and durability in shoe soles.
Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the manufacturing of rubberized components for inflatable boats, providing durability in marine environments.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the production of rubberized components for the electronics industry, including seals for electronic devices.
Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized components for the production of inflatable airbags in automotive safety systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the textile industry, including rollers for fabric processing.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the formulation of rubberized components for the production of conveyor belts used in the mining and aggregates industry.

Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the manufacturing of rubberized components for the production of automotive belts, ensuring reliability and durability.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a crucial role in the formulation of rubber compounds for the production of seals and gaskets used in plumbing applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for roller coasters, providing a combination of strength and flexibility.
In the field of household appliances, ZBED is used in the formulation of rubberized components for various applications, including gaskets for dishwashers.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds application in the creation of rubberized components for industrial hoses, ensuring resistance to chemicals and abrasion.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the production of rubberized components for the construction industry, including seals for doors and windows.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the formulation of rubber compounds for the production of durable and weather-resistant roofing materials.
Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the manufacturing of rubberized components for the production of anti-vibration mounts used in machinery.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the formulation of rubberized components for the production of conveyor belts used in the food processing and packaging industry.
In the realm of leisure and recreation, ZBED is used in the fabrication of rubberized components for playground surfaces, ensuring safety and resilience.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the medical industry, including seals for medical devices and equipment.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the creation of rubberized components for water and wastewater treatment plants, providing chemical resistance.

Zinc Dibenzyl Dithiocarbamate (ZBED) finds use in the formulation of rubberized components for the production of seals and gaskets in marine applications.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the manufacturing of rubberized components for the production of belts and pulleys used in mechanical power transmission systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the formulation of rubberized components for the production of inflatable structures used in temporary shelters and events.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the production of rubberized components for the agricultural industry, including conveyor belts for grain handling.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the formulation of rubberized components for the production of seals and gaskets used in industrial machinery.

Zinc Dibenzyl Dithiocarbamate (ZBED) is applied in the manufacturing of rubberized components for the production of vibration isolation mounts used in electronic equipment.
Zinc Dibenzyl Dithiocarbamate (ZBED) is used in the formulation of rubberized components for the production of conveyor belts used in the mining and aggregates industry.

Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the creation of rubberized components for the production of belts and hoses used in air handling and HVAC systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) is employed in the formulation of rubber compounds for the production of durable and slip-resistant surfaces for sports and recreational facilities.
Zinc Dibenzyl Dithiocarbamate (ZBED) contributes to the production of rubberized components for the oil and gas industry, including seals for pipeline systems.

Zinc Dibenzyl Dithiocarbamate (ZBED) is integral in the manufacturing of rubberized components for the production of conveyor belts used in material handling systems.
Zinc Dibenzyl Dithiocarbamate (ZBED) is utilized in the formulation of rubberized components for the production of inflatable structures used in the aerospace industry.
Zinc Dibenzyl Dithiocarbamate (ZBED) plays a role in the creation of rubberized components for the automotive industry, including rubber seals for doors and windows.



DESCRIPTION


Zinc Dibenzyl Dithiocarbamate (ZBED) is a chemical compound with the molecular formula C30H32N2S4Zn.
Recognized by its CAS number 14726-36-4, ZBED is commonly used in rubber processing.

Zinc Dibenzyl Dithiocarbamate (ZBED) has a melting point in the range of 183-188 °C, ensuring stability under elevated temperatures.
With a molecular weight of 614.22 g/mol, ZBED serves as an effective vulcanization accelerator in the rubber industry.
Zinc Dibenzyl Dithiocarbamate (ZBED)'s low solubility in rubbers such as NR, SBR, IIR, and EPDM makes it suitable for various applications.

Zinc Dibenzyl Dithiocarbamate (ZBED) is often utilized as a safe-processing secondary accelerator, enhancing the vulcanization process.
As a primary accelerator in latex, ZBED contributes to the production of latex goods with improved properties.

Zinc Dibenzyl Dithiocarbamate (ZBED) is known for its high resistance to hydrolysis, imparting durability to rubber products.
Zinc Dibenzyl Dithiocarbamate (ZBED) exhibits fast acceleration at higher vulcanization temperatures, making it versatile in rubber manufacturing.
Zinc Dibenzyl Dithiocarbamate (ZBED) is recognized for its low nitrosamine potential, a desirable characteristic in rubber processing.

In rubber sheeting, extrusions, and latex products, ZBED showcases its versatility in different manufacturing processes.
Supplied as a 100% powder in 20kg bags, ZBED is convenient to handle and incorporate into rubber formulations.
Zinc Dibenzyl Dithiocarbamate (ZBED)'s density of 1.42 g/cm³ at 20℃ influences its physical characteristics and behavior in rubber compounds.

Zinc Dibenzyl Dithiocarbamate (ZBED)'s minimal water solubility of 2.3μg/L at 20℃ contributes to its stability in wet conditions.
In its powdered form, ZBED is visually identified as a white to off-white substance, aiding in industrial applications.
With a vapor pressure of 0.001 Pa at 25℃, ZBED demonstrates low volatility, ensuring safe handling.

Zinc Dibenzyl Dithiocarbamate (ZBED)'s solubility of 44.7 mg/L in organic solvents at 20 ℃ enhances its compatibility in rubber processing.
With a LogP value of 4.29 at 20℃, ZBED's partitioning behavior is influenced by its chemical properties.
Beyond its role in rubber processing, ZBED is an analytical tool for detecting copper in plant and biological tissues.

Zinc Dibenzyl Dithiocarbamate (ZBED) has found application in preparing dithiocarbamate ligands, contributing to gold nanoparticle stabilization.
Supplied in a 70% dispersion in an EPR polymeric binder, ZBED ensures ease of handling and dispersion in rubber formulations.

Acting as a non-discoloring and non-staining accelerator, Zinc Dibenzyl Dithiocarbamate (ZBED) maintains the quality and aesthetics of rubber products.
Zinc Dibenzyl Dithiocarbamate (ZBED) serves as an accelerator for latex dispersions and cements, optimizing the vulcanization process in rubber manufacturing.
The polymer-bound dispersion of Zinc Dibenzyl Dithiocarbamate (ZBED) enhances plant safety and quality, providing better uniformity of mix at low temperatures during processing.



PROPERTIES


Chemical Formula: C30H32N2S4Zn
CAS Registry Number: 14726-36-4
CBNumber: CB1110519
Molecular Weight: 614.22 g/mol
MDL Number: MFCD00014470
Melting Point: 183-188 °C
Boiling Point: 330°C (at 101 325 Pa)
Density: 1.42 g/cm³ (at 20°C)
Vapor Pressure: 0.001 Pa at 25°C
Solubility: Moderately soluble in benzene and ethylene dichloride; insoluble in acetone, gasoline, and water
Appearance: White to off-white powder
Color: White to off-white
Water Solubility: 2.3μg/L at 20°C
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
LogP: 4.29 at 20°C
Form: Powder
Odor: Not specified
Chemical Structure: Dithiocarbamate ligand with benzyl groups and a zinc atom.
Applications: Rubber vulcanization accelerator, analytical tool for copper detection, stabilizer for gold nanoparticles.
Handling Form: Typically supplied as a 100% powder in 20kg bags.
Compatibility: Compatible with various rubber types, including NR, SBR, IIR, and EPDM.



FIRST AID


Inhalation:

Move to Fresh Air:
If inhaled, immediately move the affected person to an area with fresh air.

Seek Medical Attention:
If respiratory irritation or breathing difficulties persist, seek medical attention promptly.


Skin Contact:


Remove Contaminated Clothing:
Take off contaminated clothing, shoes, and accessories immediately.

Wash Skin Thoroughly:
Wash the affected skin area with plenty of soap and water for at least 15 minutes.

Seek Medical Attention:
If irritation, redness, or other symptoms persist, seek medical advice.


Eye Contact:

Flush Eyes:
Rinse eyes with gently flowing water for at least 15 minutes, holding eyelids open to ensure thorough flushing.

Remove Contact Lenses:
If applicable, remove contact lenses during the rinsing process.

Seek Medical Attention:
Seek immediate medical attention if irritation, redness, or other eye-related symptoms persist.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting unless directed to do so by medical personnel.

Seek Medical Attention:
Immediately seek medical attention and provide the affected person with a copy of the product's SDS.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety glasses or goggles, and protective clothing.
Use respiratory protection if the potential for dust or vapors is present.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.

Avoid Contact:
Avoid skin contact and inhalation of dust or vapors.
Do not eat, drink, or smoke while handling the substance.

Hygiene Practices:
Wash hands and face thoroughly after handling.
Launder contaminated clothing before reuse.

Storage:
Store ZBED in a cool, dry, and well-ventilated area.
Keep away from incompatible materials, such as strong acids, bases, and oxidizing agents.

Storage Containers:
Use appropriate containers made of compatible materials (e.g., stainless steel, polyethylene) to store ZBED.
Ensure containers are tightly sealed to prevent contamination and moisture absorption.

Segregation:
Segregate from incompatible substances to prevent reactions or contamination.

Handling Equipment:
Use dedicated equipment or ensure proper cleaning of shared equipment to prevent cross-contamination.


Storage Conditions:

Temperature:
Store ZBED at temperatures consistent with recommendations to prevent degradation or changes in properties.

Light Exposure:
Store away from direct sunlight or other intense light sources to prevent degradation.

Moisture Control:
Avoid exposure to moisture or humidity to prevent clumping or changes in solubility.

Fire Precautions:
Keep away from ignition sources and avoid storing near combustible materials.
Follow local regulations and guidelines for storing potentially flammable substances.

Labeling:
Clearly label storage areas with proper signage indicating the presence of ZBED and associated hazards.
Keep containers properly labeled with product information.

Emergency Response:
Have appropriate firefighting equipment, spill response materials, and emergency measures in place.

Training:
Ensure that personnel handling and storing ZBED are trained in safe practices and emergency response procedures.

Regulatory Compliance:
Comply with local, regional, and national regulations regarding the storage and handling of hazardous substances.

Periodic Inspection:
Regularly inspect storage areas for leaks, damage, or other conditions that may compromise the integrity of containers.


Emergency Procedures:

Spill Response:
In the event of a spill, follow established spill response procedures outlined in the SDS.
Wear appropriate PPE during cleanup.

Leak Containment:
Contain leaks to prevent the spread of the substance.
Use absorbent materials to control and clean up spills.

Disposal:
Dispose of ZBED in accordance with local regulations and guidelines.
Do not discharge into water sources or sewage systems without proper treatment and permission.



SYNONYMS


ZBDC
ZBEC-70
BENZYL ZIMATE
Accelerator ZBEC (DBZ)
ZINC DIBENZYLDITHIOCARBAMATE
N,N-dibenzylcarbamodithioate
Zinkbis(dibenzyldithiocarbamat)
ZINC N,N-DIBENZYLDITHIOCARBAMATE
Zinc(II) Dibenzyldithiocarbamate
ZBEC
Dibenzylcarbamodithioic acid zinc salt
Dibenzyldithiocarbamic acid zinc salt
Zinc bis(dibenzylcarbamodithioate)
Bis(dibenzylcarbamodithioato-S,S')zinc
Zineb
Benzyl Zimate
N,N-Dibenzyl-N,N-dimethyldithiocarbamate zinc salt
Zimate
Zinc bis(N,N-dibenzylthiocarbamoyl)oxide
Bis(N,N-dibenzylcarbamodithioato)zinc
N,N-Dibenzylcarbamic acid zinc salt
Zinc, bis(carbamodithioato-S,S')dibenzyl-
ZBED-70
Zinc dibenzylcarbamodithioate
Zinc N,N-dibenzyl-N,N-diethyldithiocarbamate
Zinc dibenzylthiocarbamate
Dibenzyldithiocarbamate zinc salt
Zinc dibenzylthiuram disulfide
ZBED Accelerator
Bis(dibenzylcarbamodithioato-S,S') zinc
Zinc bis(N,N-dibenzylcarbamodithioate)
N,N-Dibenzylcarbamic acid zinc salt
Zinc dibenzylcarbamodithiocinate
Zinc bis(dibenzyldithiocarbamoyl)oxide
Zinc N,N-dibenzyl-N,N-diisobutyldithiocarbamate
Dibenzyl(dithiocarbamoylthio)zinc
Zimate ZBED
Zinc bis(N,N-dibenzylcarbamodithioate)
Zinc dibenzylcarbodithioate
Zinc bis(N,N-dibenzylcarbamodithiocinate)
Zinc dibenzyl-N,N-dimethylthiocarbamate
ZBED-75
N,N-dibenzyl-N,N-diisopropyldithiocarbamic acid zinc salt
N,N-dibenzylcarbamodithioic acid zinc salt
Bis(dibenzylcarbamodithioato)zinc oxide
Zinc N,N-dibenzyl-N,N-dipropyldithiocarbamate
Zinc N,N-dibenzyl-N,N-diethyldithiocarbamic acid
N,N-dibenzyl-N,N-dipropyldithiocarbamic acid zinc salt
Zinc bis(dibenzylcarbamodithioato-S,S') oxide
Dibenzyldithiocarbamoyl zinc
Zinc N,N-dibenzyl-N,N-dipropylcarbamodithiocinate
Zinc bis(N,N-dibenzylcarbamodithioato)oxide
N,N-dibenzyl-N,N-diethyldithiocarbamic acid zinc salt
Zinc bis(dibenzyldithiocarbamic acid) oxide
Zinc N,N-dibenzyl-N,N-dipropylthiocarbamate
Zinc dibenzyl-N,N-diethylthiocarbamic acid
Zinc N,N-dibenzyl-N,N-dimethylthiocarbamic acid
Zinc bis(N,N-dibenzylthiocarbamoyl)oxide
Dibenzyl(thiocarbamoylthio)zinc
ZINC DIBENZYLDITHIOCARBAMATE (ZBEC)
Zinc Dibenzyldithiocarbamate (ZBEC) is zinc dibenzyl dithiocarbamate-based vulcanization accelerator.
Zinc Dibenzyldithiocarbamate (ZBEC) is an accelerator for the vulcanization of natural- and synthetic rubbers


CAS Number: 14727-36-4
EC Number: 238-778-0
MDL Number: MFCD00014470
Molecular Formula: C30H28N2S4Zn



14726-36-4, Zinc dibenzyldithiocarbamate, Dibenzyldithiocarbamic acid zinc salt, Zinc(II) dibenzyldithiocarbamate, Dibenzyldithiocarbamic acid, zinc salt, zinc;N,N-dibenzylcarbamodithioate, Dibenzyldithiocarbamicacidzincsalt, (N,N-Dibenzyldithiocarbamato)zinc, 33RO266515, zinc(2+) bis((dibenzylcarbamothioyl)sulfanide), Zinc bis(dibenzyldithiocarbamate), UNII-33RO266515, EINECS 238-778-0, starbld0016580, EC 238-778-0, SCHEMBL78980, DTXSID20893254, AKOS015839259, Dibenzyldithiocarbamic Acid Zinc(II) Salt, CS-0205479, D0157, FT-0689257, NS00078163, 5-chloro-2-methoxypyridin-3-yl-3-boronic?acid, A854240, Q27256296, (T-4)-Bis(bis(phenylmethyl)carbamodithioato-S,S')zinc, Zinc, bis(bis(phenylmethyl)carbamodithioato-S,S')-, (beta-4)-, Zinc, bis(bis(phenylmethyl)carbamodithioato-kappaS,kappaS')-, (T-4)-, Zinc, bis(N,N-bis(phenylmethyl)carbamodithioato-kappaS,kappaS')-, (T-4)-, Zinc dibenzyl dithiocarbamate, ZBEC, ZBDC, zbdc, zbec, benzyl zimate, BENZYL ZIMATE, dibenzyldithiocarbamate, zinc dibenzyldithiocarbamate, ZINC DIBENZYLDITHIOCARBAMATE, zinc dibenzyl dithiocarbamate, zinkbis(dibenzyldithiocarbamat), zinc n,n-dibenzyldithiocarbamate, ZINC N,N-DIBENZYLDITHIOCARBAMATE, zinc bis(dibenzyldithiocarbamate), bibenzyldithiocarbamicacidzincsalt, zinc bis(dibenzylcarbamodithioate), zinc (dibenzylamino)methanedithioate, DIBENZYLDITHIOCARBAMIC ACID, ZN SALT, dibenzyldithiocarbamic acid, zn salt, DIBENZYLDITHIOCARBAMIC ACID ZINC SALT, dibenzyldithiocarbamic acid zinc salt, Zinc bis(N,N-dibenzyldithiocarbamate), zinc bis(n,n-dibenzyldithiocarbamate), Dibenzyldithiocarbamic Acid, Zinc Salt, n,n-dibenzyl dithiocarbamic acid zine salt, bis[[(dibenzylamino)(thiocarbonyl)]thio] zinc, s']-bis[bis(phenylmethyl)carbamodithioato-(beta-4)-zin, bis[bis(phenylmethyl)carbamodithioato-s,s']-,(t-4)-zinc, bis[bis(phenylmethyl)carbamodithioato-S,S']-,(T-4)-Zinc, zinc,bis[bis(phenylmethyl)carbamodithioato-s,s']-,(t-4)-, zinc, bisbis(phenylmethyl)carbamodithioato-.kappa.s,.kappa.s-, (t-4)-, DIBENZYLDITHIOCARBAMIC ACID ZINC SALT, DIBENZYLDITHIOCARBAMIC ACID, ZN SALT, BENZYL ZIMATE, ZBDC, Zinc bis(N,N-dibenzyldithiocarbamate), ZINC DIBENZYLDITHIOCARBAMATE, ZINC N,N-DIBENZYLDITHIOCARBAMATE, bis[bis(phenylmethyl)carbamodithioato-S,S’]-,(T-4)-Zinc,Zinc, dibenzyldithiocarbamate, Zinc dibenzyl dithiocarbamate, ZBEC, ZBED, ZBeDC, Zinc bis (dibenzyl dithiocarbamate), Zinc,bis(dibenzyldithiocarbamato)- (7CI,8CI), Zinc,bis[bis(phenylmethyl)carbamodithioato-kS,kS']-, (T-4)- (9CI), (N,N-Dibenzyldithiocarbamato)zinc, Arazate, Bis(dibenzyldithiocarbamato)zinc, Nocceler ZTC, Rhenogran ZBEC70, Vulkacit ZBEC, ZBEC, DIBENZYLDITHIOCARBAMIC ACID ZINC SALT, DIBENZYLDITHIOCARBAMIC ACID, ZN SALT, BENZYL ZIMATE, ZBDC, Zinc bis(N,N-dibenzyldithiocarbamate), ZINC DIBENZYLDITHIOCARBAMATE, ZINC N,N-DIBENZYLDITHIOCARBAMATE, ZBDC, ZBEC-70, ZBEC(ZBDC), BENZYL ZIMATE, Accelerator ZBEC (DBZ), ZINC DIBENZYLDITHIOCARBAMATE, N,N-dibenzylcarbamodithioate, Zinkbis(dibenzyldithiocarbamat), ZINC N,N-DIBENZYLDITHIOCARBAMATE, Zinc(II) Dibenzyldithiocarbamate, Zinc,bis[N,N-bis(phenylmethyl)carbamodithioato-κS,κS′]-,(T-4)-, Zinc,bis(dibenzyldithiocarbamato)-, Zinc,bis[bis(phenylmethyl)carbamodithioato-S,S′]-,(T-4)-, Zinc,bis[bis(phenylmethyl)carbamodithioato-κS,κS′]-,(T-4)-, (T-4)-Bis[N,N-bis(phenylmethyl)carbamodithioato-κS,κS′]zinc, Zinc dibenzyldithiocarbamate, Bis(dibenzyldithiocarbamato)zinc, Rhenogran ZBEC 70, Vulkacit ZBEC, Nocceler ZTC, Arazate, Perkacit ZBEC, Vulkacit ZBEC/C, (N,N-Dibenzyldithiocarbamato)zinc, ZBEC, Sanceler Z-BE, DBZ, Avorator ZBEC 70GE, Accelerator ZBEC, Nocceler Z, 137427-50-0, 138-54-5, 56803-46-4, DIBENZYLDITHIOCARBAMIC ACID ZINC SALT, DIBENZYLDITHIOCARBAMIC ACID, ZN SALT, BENZYL ZIMATE, ZBDC, Zinc bis(N,N-dibenzyldithiocarbamate), ZINC DIBENZYLDITHIOCARBAMATE, ZINC N,N-DIBENZYLDITHIOCARBAMATE, bis[bis(phenylmethyl)carbamodithioato-S,S’]-,(T-4)-Zinc,



Zinc Dibenzyldithiocarbamate (ZBEC) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Zinc Dibenzyldithiocarbamate (ZBEC) is zinc dibenzyl dithiocarbamate-based vulcanization accelerator.


Zinc Dibenzyldithiocarbamate (ZBEC) is an accelerator for the vulcanization of natural- and synthetic rubbers.
Zinc Dibenzyldithiocarbamate (ZBEC) has a high level of processing safety compared with conventional dithiocarbamate accelerators.
In compounds containing thiazole or sulfenamide accelerators, Zinc Dibenzyldithiocarbamate (ZBEC) has an activating effect.


Zinc Dibenzyldithiocarbamate (ZBEC) contains ethylene propylene diene rubber as a binder.
Zinc Dibenzyldithiocarbamate (ZBEC) is suitable for technical rubber articles based on NR, EPDM, IR, SBR, NBR and IIR.
Zinc Dibenzyldithiocarbamate (ZBEC) is particularly suitable for light or bright-colored rubber articles.


Zinc Dibenzyldithiocarbamate (ZBEC) has a shelf life of 2 years.
Zinc Dibenzyldithiocarbamate (ZBEC) is a very fast primary or secondary accelerator for natural and synthetic rubber.
Zinc Dibenzyldithiocarbamate (ZBEC) is non-staining, non discoloring and is safer processing than ZDBC.


Zinc Dibenzyldithiocarbamate (ZBEC) is also useful as a secondary accelerator for the continuous vulcanization of butyl rubber extrusions.
Zinc Dibenzyldithiocarbamate (ZBEC) has found usefulness in minimizing harmful nitrosoamines.
Nitrosodibenzylamine is not carcinogenic, according to publish literature.


Zinc Dibenzyldithiocarbamate (ZBEC) is a white to grayish white powder boiling point: 408.3 ºC at 760mmHg Melting point: 183-188 °C Flash point: 200.8 C.
Zinc Dibenzyldithiocarbamate (ZBEC) is stable at room temperature in closed containers under normal storage and handling conditions.
Store Zinc Dibenzyldithiocarbamate (ZBEC) in a tightly closed container.


Store Zinc Dibenzyldithiocarbamate (ZBEC) in a cool, dry, Well-ventilated area away from incompatible substances.
Steam pressure of Zinc Dibenzyldithiocarbamate (ZBEC) is 7.06E-07mmHg at 25°C
Zinc Dibenzyldithiocarbamate (ZBEC) is a nonflammable.


Zinc Dibenzyldithiocarbamate (ZBEC) is an accelerator for NR latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is odorless.
Zinc Dibenzyldithiocarbamate (ZBEC) is a dithiocarbamate accelerator for rubber compounds.


Zinc Dibenzyldithiocarbamate (ZBEC) is recognised to have low nitrosamine potential.
Within the range of zinc dithiocarbamates, Zinc Dibenzyldithiocarbamate (ZBEC) provides the longest scorch resistance as well as excellent prevulcanization resistance in latex


Zinc Dibenzyldithiocarbamate (ZBEC) is a white powder (granular).
The relative density of Zinc Dibenzyldithiocarbamate (ZBEC) is 1.14.
The melting point of Zinc Dibenzyldithiocarbamate (ZBEC) is not less than 178 degree.


Zinc Dibenzyldithiocarbamate (ZBEC) is soluble in ethanol, benzene and chloroform, insoluble in water.
Zinc Dibenzyldithiocarbamate (ZBEC) is stable.
Zinc Dibenzyldithiocarbamate (ZBEC) has fast at higher vulcanisation temperatures.



USES and APPLICATIONS of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) is used in formulation or re-packing, at industrial sites and in manufacturing.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in the following products: polymers.
Release to the environment of Zinc Dibenzyldithiocarbamate (ZBEC) can occur from industrial use: formulation in materials.


Zinc Dibenzyldithiocarbamate (ZBEC) is used in the following products: polymers.
Zinc Dibenzyldithiocarbamate (ZBEC) is used for the manufacture of: rubber products, and chemicals.
Release to the environment of Zinc Dibenzyldithiocarbamate (ZBEC) can occur from industrial use: as processing aid and in the production of articles.


Release to the environment of Zinc Dibenzyldithiocarbamate (ZBEC) can occur from industrial use: manufacturing of the substance.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in rubber polymer.
Zinc Dibenzyldithiocarbamate (ZBEC) is used safe-processing secondary accelerator.


Zinc Dibenzyldithiocarbamate (ZBEC) can be used as primary in latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used high resistance to hydrolysis; low solubility in rubbers.
Zinc Dibenzyldithiocarbamate (ZBEC) is used fast at higher vulcanisation temperatures.


Zinc Dibenzyldithiocarbamate (ZBEC) is recognised to have low nitrosamine potential.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in sheeting, extrusions and latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in NR, SBR, IIR and EPDM


Zinc Dibenzyldithiocarbamate (ZBEC)is a useful analytical tool for the detection of copper in plants and biological tissues.
Zinc Dibenzyldithiocarbamate (ZBEC) is also used to prepare dithiocarbamate ligands for stabilizing gold nanoparticles.
Zinc Dibenzyldithiocarbamate (ZBEC) is used accelerator for latex dispersions and cements


Zinc Dibenzyldithiocarbamate (ZBEC) is used ultra-accelerator for NR and synthetic rubbers.
Zinc Dibenzyldithiocarbamate (ZBEC) is often used as a secondary accelerator with
thiazoles.


Zinc Dibenzyldithiocarbamate (ZBEC) has to be used with sulfur and zinc oxide.
Zinc Dibenzyldithiocarbamate (ZBEC) disperses easily in dry rubber. Zinc Dibenzyldithiocarbamate (ZBEC) does not affect latex stability.
In wet rubber, Zinc Dibenzyldithiocarbamate (ZBEC) gives an excellent prevulcanization resistance.


For compounds containing a high level of silica, Zinc Dibenzyldithiocarbamate (ZBEC) improves filler-rubber bound.
Zinc Dibenzyldithiocarbamate (ZBEC) is used non-colouring and non-staining.
General rubber goods use of Zinc Dibenzyldithiocarbamate (ZBEC): latex articles, dispersions, adhesives, wire and cable, extruded sealing profiles, etc.


Zinc Dibenzyldithiocarbamate (ZBEC) is typically used to replace more conventional dithiocarbamates in compounds to reduce or eliminate the generation of potentially hazardous nitrosamines during the vulcanization process.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in sheeting, extrusions and latex. Used in NR, SBR, IIR and EPDM.


Application of Zinc Dibenzyldithiocarbamate (ZBEC): Safe-processing secondary accelerator.
Zinc Dibenzyldithiocarbamate (ZBEC) can be used as primary in latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used high resistance to hydrolysis; low solubility in rubbers.


Zinc Dibenzyldithiocarbamate (ZBEC) is used fast at higher vulcanization temperatures.
Zinc Dibenzyldithiocarbamate (ZBEC) is recognized to have low nitrosamine potential.
Zinc Dibenzyldithiocarbamate (ZBEC) is used in sheeting, extrusions and latex.


Zinc Dibenzyldithiocarbamate (ZBEC) is used in NR, IIR, SBR, and EPDM.
Zinc Dibenzyldithiocarbamate (ZBEC) can be used as primary in latex.
Zinc Dibenzyldithiocarbamate (ZBEC) is used high resistance to hydrolysis; low solubility in rubbers.


Zinc Dibenzyldithiocarbamate (ZBEC) has also been used in the preparation of dithiocarbamate ligand for the stabilization of gold nanoparticles.
Zinc Dibenzyldithiocarbamate (ZBEC) uses and applications include: Accelerator, stabilizer for rubber, latex dispersions, cements; accelerator in food-contact rubber articles for repeated use; activator for thiazoles; in food packaging adhesives



Zinc Dibenzyldithiocarbamate (ZBEC) has also been used to prepare dithiocarbamate ligands for the stabilization of gold nanoparticles.
Rubber accelerant, Zinc Dibenzyldithiocarbamate (ZBEC) is only used in the production of cable, tires, hose, tape, bright and transparent products, shoes, electronic products, etc.


Zinc Dibenzyldithiocarbamate (ZBEC) is a useful analytical tool, used in the detection of copper in plant and biological tissues.
Zinc Dibenzyldithiocarbamate (ZBEC) is a useful analytical tool for the detection of copper in plants and biological tissues.
Zinc Dibenzyldithiocarbamate (ZBEC) is used for the manufacture of: rubber products, and chemicals.



SCIENTIFIC RESEARCH APPLICATIONS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
*Copper Determination in High Purity Metals:
Zinc Dibenzyldithiocarbamate (ZBEC)was used for the rapid spectrophotometric determination of copper in high purity metals, offering more sensitivity than the diethyldithiocarbamate method.

*Copper Analysis in Steels:
Employed for the rapid spectrophotometric determination of copper in a wide variety of steels, where Zinc Dibenzyldithiocarbamate (ZBEC)'s acidity range and color stability were advantageous.

*Thermal Decomposition in Rubber Vulcanization:
Investigated for its role in the thermal decomposition of rubber vulcanization, specifically as a precursor for N-nitrosodibenzylamine in processed hams.

*Allergen Testing in Rubber Gloves:
Studied for its role as a vulcanizing agent in rubber gloves and its potential allergenic effects.

*Corrosion Inhibitor for Copper:
Demonstrated as an effective and low-toxicity corrosion inhibitor for copper, forming a hydrophobic film to protect against corrosion.

*Determination of Copper in Dyes and Rubber Chemicals:
Provided a specific method for determining small amounts of copper in rubber chemicals, dyes, and dyed fabrics.

*Copper Determination in Biological Tissues:
Utilized for the direct determination of copper in blood and liver tissues after wet digestion.

*Estimating Copper in Water:
Proven effective in estimating copper in water, showing high accuracy and repeatability.

*Dithiocarbamate Release from Latex Vulcanizates:
Examined for the release of dithiocarbamate accelerators, including Zinc Dibenzyldithiocarbamate (ZBEC), from natural rubber latex vulcanizates.

*Zinc Oxide Nanoparticles in Biomedical Applications:
Related to zinc oxide nanoparticles, these studies explore the application of similar compounds in biomedicine, including their role in anticancer, antibacterial fields, and bioimaging.



MAJOR APPLICATIONS AND PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
- Zinc Dibenzyldithiocarbamate (ZBEC) has been developed as a safe secondary amine dithiocarbamate.
- Zinc Dibenzyldithiocarbamate (ZBEC) is not carcinogenic according to published literature.
- Zinc Dibenzyldithiocarbamate (ZBEC) is used as a primary or secondary ultra-accelerator for thiazole and sulfenamide cure systems for general-purpose polymers (NR, SBR, IIR, EPDM).
Zinc Dibenzyldithiocarbamate (ZBEC) can be used as a primary ultra accelerator in special applications as well as in latex.
- Within the range of zinc dithiocarbamates, Zinc Dibenzyldithiocarbamate (ZBEC) provides the longest scorch resistance as well as excellent prevulcanization resistance in latex.



CHEMICAL PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) is a white powder.
Zinc Dibenzyldithiocarbamate (ZBEC) is moderately soluble in benzene and ethylene dichloride; insoluble in acetone, gasoline, and water.



PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) is white powder (granular).
Zinc Dibenzyldithiocarbamate (ZBEC) is soluble in alcohol, benzene and chloroform, insoluble in water.



SYNTHESIS ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The synthesis of Zinc Dibenzyldithiocarbamate (ZBEC) involves the reaction of zinc oxide with dibenzyldithiocarbamic acid or its salts.
Research into the synthesis of related zinc(II) dithiocarbamate complexes has shown the formation of compounds with varied coordination geometries around zinc, demonstrating the versatility of dithiocarbamate ligands in coordinating with zinc ions to form complexes with distinct molecular structures.



MOLECULAR STRUCTURE ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The molecular structure of Zinc Dibenzyldithiocarbamate (ZBEC) and its complexes has been explored through techniques such as X-ray crystallography, revealing distorted trigonal bipyramidal and tetrahedral coordination geometries around the zinc ion.
These structures highlight the bidentate chelating and bridging capabilities of the dithiocarbamate ligands, which are crucial for the formation of the complexes' molecular architecture.



CHEMICAL REACTIONS AND PROPERTIES OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Zinc Dibenzyldithiocarbamate (ZBEC) participates in various chemical reactions due to its active dithiocarbamate group.
Zinc Dibenzyldithiocarbamate (ZBEC) is known for its role in the vulcanization process of rubber, where it acts as an accelerator.
Zinc Dibenzyldithiocarbamate (ZBEC)'s thermal decomposition has been studied, indicating its potential role in nitrosamine formation, which is significant in understanding its behavior under high-temperature conditions associated with rubber processing.



PHYSICAL PROPERTIES ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The physical properties of Zinc Dibenzyldithiocarbamate (ZBEC), such as its thermal stability and solubility in various solvents, are crucial for its application in industrial processes.
Zinc Dibenzyldithiocarbamate (ZBEC)'s thermal decomposition and the stability of its complexes under different conditions have been subjects of research, providing insights into its safe handling and storage requirements.



CHEMICAL PROPERTIES ANALYSIS OF ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
The chemical properties of Zinc Dibenzyldithiocarbamate (ZBEC), including its reactivity with other compounds and its role in catalysis, have been explored.
Zinc Dibenzyldithiocarbamate (ZBEC)'s ability to form stable complexes with zinc ions and its reactions under various conditions are essential for understanding its functionality as a vulcanization accelerator and its potential in other chemical processes



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
Molecular Weight: 610.2 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 8
Exact Mass: 608.042675 g/mol
Monoisotopic Mass: 608.042675 g/mol
Topological Polar Surface Area: 72.7Ų
Heavy Atom Count: 37
Formal Charge: 0
Complexity: 230
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
CAS No.:14726-36-4
Other Names:Zinc dibenzyl dithiocarbamate
MF:C30H28S4ZnN2
EINECS No.:238-778-0
Purity:99.6% MIN
Type:Dithiocarbamates Rubber Accelerator
Usage:Rubber Auxiliary Agents
Melting point: 183-188 °C
Boiling point: 330℃[at 101 325 Pa]
Density :1.42[at 20℃]
vapor pressure: 0.001Pa at 25℃
solubility: 44.7mg/L in organic solvents at 20 ℃
form: Powder
color: White to off-white

Water Solubility: 2.3μg/L at 20℃
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
LogP: 4.29 at 20℃
Indirect Additives used in Food Contact Substances: ZINC DIBENZYLDITHIOCARBAMATE
FDA 21 CFR: 175.105; 177.2600
CAS DataBase Reference: 14726-36-4(CAS DataBase Reference)
FDA UNII: 33RO266515
EPA Substance Registry System: Zinc dibenzodithiocarbamate (14726-36-4)
Physical Form: Powder
Color: White to cream
Heat Loss (5g, 60°C, 2 hrs): 0.5% Max.
Melting Point: 178°C Min.
CAS No.: 14726-36-4
Molecular Formula: C30H28N2S4Zn
InChIKeys: InChIKey=AUMBZPPBWALQRO-UHFFFAOYSA-L

Molecular Weight: 610.21
Exact Mass: 608.042664
EC Number: 238-778-0
UNII: 33RO266515
HScode: 29302000
PSA: 121.26000
XLogP3: 8.33990
Appearance: White to off-white Powder
Melting Point: 183-188 °C
Boiling Point: 408.3ºC at 760mmHg
Flash Point: 200.8ºC
Storage Conditions: Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Vapor Pressure: 7.06E-07mmHg at 25°C
Melting point: 183-188 °C

Boiling point: 330℃[at 101 325 Pa]
density: 1.42[at 20℃]
vapor pressure: 0.001Pa at 25℃
solubility: 44.7mg/L in organic solvents at 20 ℃
form: Powder
color: White to off-white
Water Solubility: 2.3μg/L at 20℃
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
LogP: 4.29 at 20℃
CAS DataBase Reference: 14726-36-4(CAS DataBase Reference)
EPA Substance Registry System: Zinc dibenzodithiocarbamate (14726-36-4)
CAS: 14726-36-4
EINECS: 238-778-0

InChI: InChI=1/C15H15NS2/c17-15(18)16(11-13-7-3-1-4-8-13)12-14-9-5-2-6-10-14/h1-10H,11-12H2,(H,17,18)/p-1
InChIKey: AUMBZPPBWALQRO-UHFFFAOYSA-L
Molecular Formula: C30H32N2S4Zn
Molar Mass: 614.22
Density 1.42[at 20℃]
Melting Point: 183-188 °C
Boling Point: 330℃[at 101 325 Pa]
Flash Point: 200.8°C
Water Solubility: 2.3μg/L at 20℃
Solubility: 44.7mg/L in organic solvents at 20 ℃
Vapor Presure: 0.001Pa at 25℃
Appearance: White to white-like powder
Color: White to off-white
Storage Condition: Room Temprature
MDL: MFCD00014470



FIRST AID MEASURES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of ZINC DIBENZYLDITHIOCARBAMATE (ZBEC):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


ZINC DIBUTYLDITHIOCARBAMATE
Zinc Dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate has a role as an antifungal agrochemical.


CAS Number: 136-23-2
EC Number: 205-232-8
MDL number: MFCD00067274
Molecular Formula: C18H36N2S4Zn



SYNONYMS:
di-n-Butyldithiocarbamic acid,zinc salt, Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-, Zinc, bis(dibutyldithiocarbamato)-, Aceto zdbd, Bis(dibutyldithiocarbamato)zinc, Butazate, Butazate 50-D, Butyl zimate, Butyl ziram, Carbamic acid, dibutyldithio-, zinc complex, Dibutyldithiocarbamic acid zinc salt, USAF GY-5, Vulcacure, Vulkacit ldb/C, Zimate, butyl, Zinc bibutyldithiocarbamate, Zinc N,N-dibutyldithiocarbamate, Accelerator BZ powder, Butasan, Butasan vulcanization accelerator, Butazin, Nocceler BZ, Octocure ZDB-50, Perkacit ZDBC, Soxinol BZ, ZBC, Zinc bis(dibutyldithiocarbamate), Zinc di-n-butyl dithiocarbamate, bis(dibutyldithiocarbamate)zinc(II), Zinc(II) Dibutyl dithiocarbamate, Zinc bis(dibutyldithiocarbamate), Zinc N,N-dibutylcarbamodithioate, Dibutyldithiocarbamic Acid Zinc(II) Salt, carbamate-BZ, ZDBC (BZ), (Dibutyldithiocarbamato)zinc(II), Accel BZ, Aceto ZDBD, Bis(N,N-dibutyldithiocarbamato)zinc, Bis(dibutyldithiocarbamato)zinc, Butazate, Butazate 50-D, Butyl zimate, Butyl ziram, Carbamic acid, dibutyldithio-, zinc complex, Carbamodithioic acid, dibutyl-, zinc salt, Dibutyldithiocarbamic acid zinc salt, Nocceler BZ, Soxinol BZ, Vulcacure, Vulcacure ZB, Vulkacit LDB, Vulkacit LDB/C, Zimate, butyl, Zinc N,N-dibutyldithiocarbamate, Zinc bis(dibutyldithiocarbamate), Zinc dibutyldithiocarbamate, Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-, Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-, Zinc, bis(dibutyldithiocarbamato)-, [ChemIDplus] ZDBC, [HSDB], Zinc N,N-dibutyldithiocarbamate, Butyl zimate, Di-n-butyldithiocarbamic Acid Zinc Salt, Butasan, Butazate, Butazin, Nocceler BZ, Soxinol BZ, ZBC, Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-, Zinc bis(dibutyldithiocarbamate), NSC-3880, ZINC BIS(DIBUTYLDITHIOCARBAMATE), ZINC DIBUTYLDITHIOCARBAMATE, ZINC DIBUTYLDITHIOCARBAMATE [INCI], ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-, ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB], ZINCDIBUTYLD ITHIOCARBAMATE, 2,6-bis(dibutylamino)-1,3,5,7-tetrathia-4-zincaspiro[3.3]hepta-1,5-diene-1,5-bis(ylium), Accelerator BZ powder, Aceto zdbd, Bis(dibutyldithiocarbamato)zinc, Bis(N,N-dibutylthiocarbamoylthio)zinc, Butasan, Butasan vulcanization accelerator, Butazate, Butazate 50-D, Butazin, Butyl zimate, Butyl ziram, Carbamic acid, dibutyldithio-, zinc complex, di-n-Butyldithiocarbamic acid,zinc salt, Dibutyldithiocarbamic acid zinc salt, Nocceler BZ, Octocure ZDB-50, Perkacit ZDBC, Soxinol BZ, Vulcacure, Vulkacit ldb/C, ZBC, Zimate, butyl, Zinc bibutyldithiocarbamate, Zinc di-n-butyl dithiocarbamate, Zinc dibutyldithiocarbamate, Zinc N,N-dibutyldithiocarbamate, Zinc(II) bis(N,N-diisobutyldithiocarbamate), Zinc, bis(dibutylcarbamodithioato-S,S')-, Zinc, bis(dibutyldithiocarbamato)-, USAF GY-5, (T-4)-Bis(dibutylcarbamodithioato-kappas,kappas')zinc, Bis(dibutyldithiocarbamato)zinc, Dibutyldithiocarbamate zinc salt, Zinc bis(dibutyldithiocarbamate), Zinc bis(dibutyldithiocarbamoyl)disulfide, Zinc bis(dibutyldithiocarbamoyl)disulphide, Zinc bis(dibutylthiocarbamoyl)disulfide, Dibutyldithiocarbamic acid zinc salt, Zinc bis(dibutyldithiocarbamic acid), Zinc bis(dibutylthiocarbamoyl)disulphide, Zinc dibutyldithiocarbamic acid, Zinc di-N-butyldithiocarbamic acid, Butasan, Butazate, Butazin, Butyl Zimate, Butyl Ziram, Nocceler BZ, Soxinol, ZBC, ZDBC, Zinc bis(dibutyldithiocarbamate), Zinc N, N-dibutyldithiocarbamate, Butasan, Butazate, Butazin, Butyl Zimate, Nocceler BZ, Soxinol BZ, ZBC, Zinc dibutyldithiocarbamate, Zinc dibutyldithiocarbamate, 136-23-2, Zinc(II) Dibutyldithiocarbamate, Zinc bis(dibutyldithiocarbamate), zinc;N,N-dibutylcarbamodithioate, DTXSID0021462, Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-, DTXCID501462, Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-, CAS-136-23-2, Bis(dibutyldithiocarbamato)zinc, zinc bis(dibutylcarbamodithioate), HNM5J934VP, SCHEMBL35745, dibutyldithiocarbamate zinc salt, ZINCDIBUTYLDITHIOCARBAMATE, CHEMBL2373108, BOXSVZNGTQTENJ-UHFFFAOYSA-L, CHEBI:144323, NSC-3880, Tox21_113038, Tox21_202601, NSC-36548, AKOS015839728, zinc bis(dibutylthiocarbamoyl)disulfide, zinc bis(dibutyldithiocarbamoyl)disulfide, Dibutyldithiocarbamic Acid Zinc(II) Salt, NCGC00188440-01, NCGC00260149-01, zinc bis(dibutyldithiocarbamoyl)disulphide, ZINC DIBUTYLDITHIOCARBAMATE [INCI], CS-0152117, D0227, NS00079390, E81950, ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-, ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB], (T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc, Q27280015, NSC-36548



Zinc Dibutyldithiocarbamate will prevulcanise latex; gives high modulus and transparency.
Zinc Dibutyldithiocarbamate has high solubility in rubbers.
Zinc Dibutyldithiocarbamate is a chemical compound that forms a complex with fatty acids.


Zinc Dibutyldithiocarbamate is found in reaction solutions, where it reacts with hydrochloric acid and boron nitride to form zinc diethyldithiocarbamate.
Zinc Dibutyldithiocarbamate is a vulcanization accelerator for natural rubber and latex and a stabilizer for rubber-based adhesive systems, isobutylene-isoprene copolymers and polypropylene.


Zinc Dibutyldithiocarbamate is used in a number of rubber and rubber-based materials for food packaging and food handling, e.g. conveyor belts.
Zinc Dibutyldithiocarbamate is contact allergens that cross-react in some individuals.
Zinc Dibutyldithiocarbamate, like many low-molecular-weight contact allergens, can only trigger an immune response when bound to a protein in the form of an immunogenic protein–hapten complex.


Haptenation of epidermally relevant skin proteins by Zinc Dibutyldithiocarbamate has not been reported despite the numerous studies on the disposition and systemic toxicity of Zinc dibutyldithiocarbamate.
Zinc Dibutyldithiocarbamate is one of numerous organometallic compounds manufactured.


Organometallics are useful reagents, catalysts, and precursor materials with applications in thin film deposition, industrial chemistry, pharmaceuticals, LED manufacturing, and others.
Zinc Dibutyldithiocarbamate is a white solid with a pleasant odor.


Zinc Dibutyldithiocarbamate is a white to cream-colored powder.
Zinc Dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate has a role as an antifungal agrochemical.


Zinc Dibutyldithiocarbamate is a dermatological sensitizer and allergen.
Sensitivity to Zinc Dibutyldithiocarbamate may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.


Zinc Dibutyldithiocarbamate contains a dibutyldithiocarbamate and a zinc(2+).
Zinc Dibutyldithiocarbamate is functionally related to a dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate is a dermatological sensitizer and allergen.


Sensitivity to Zinc Dibutyldithiocarbamate may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.



USES and APPLICATIONS of ZINC DIBUTYLDITHIOCARBAMATE:
Zinc Dibutyldithiocarbamate is used as an activator and accelerator in natural rubber synthetic latexes.
Zinc Dibutyldithiocarbamate is used Antidegradant, and accelerator, natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, ethylene-propylene-diene terpolymers.


Zinc Dibutyldithiocarbamate is used Antioxidant in rubber-based adhesive.
Zinc Dibutyldithiocarbamate is used condoms and diaphragms.
Zinc Dibutyldithiocarbamate is used cosmetic biocide for skin cleanser and odor prevention.


Zinc Dibutyldithiocarbamate is used gloves (household, work, or hospital).
Zinc Dibutyldithiocarbamate is used heavy rubber products used in industry.
Zinc Dibutyldithiocarbamate is used leather shoes (insoles, adhesives, and linings).


Zinc Dibutyldithiocarbamate is used medical devices.
Zinc Dibutyldithiocarbamate is used renal dialysis equipment.
Zinc Dibutyldithiocarbamate is used rubber in elasticized undergarments and clothing.


Zinc Dibutyldithiocarbamate is used rubber pillows and sheets.
Zinc Dibutyldithiocarbamate is used rubber shoes (sneakers, tennis shoes, and the like).
Zinc Dibutyldithiocarbamate is used sponge makeup applicators and rubber eyelash curlers.


Zinc Dibutyldithiocarbamate is used stabilizer in cement.
Zinc Dibutyldithiocarbamate is used swim wear.
Zinc Dibutyldithiocarbamate is used tires.


Zinc Dibutyldithiocarbamate is used Toys.
Zinc Dibutyldithiocarbamate belongs to the class of organic compounds known as organic transition metal salts.
These are organic salt compounds containing a transition metal atom in its ionic form.


Zinc Dibutyldithiocarbamate is used in Adhesives, Condoms and diaphragms, Disinfectants, repellents, fungicides, and insecticides.
Zinc Dibutyldithiocarbamate is used in agriculture, Gloves (household, work, or hospital), Heavy rubber products used in industry, and Leather shoes (insoles, adhesives, linings).


Zinc Dibutyldithiocarbamate is used medical devices, Renal dialysis equipment, Rubber in elasticized undergarments and clothing, Rubber pillows and sheets, Rubber shoes (sneakers, tennis shoes, etc.), Soaps and shampoos, Sponge makeup applicators and rubber eyelash curlers, Swim wear, and Tires and toys.
Zinc Dibutyldithiocarbamate is used as accelerator (rubber vulcanization, latex dispersions, and cements), ultra-accelerator for lubricating oil additives, and stabilizer in food packaging and handling.


Zinc Dibutyldithiocarbamate is used as an absorbent and sample preparation agent in uv spectroscopy.
Zinc Dibutyldithiocarbamate is used activator, antidegradant and accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethylene-propylene-diene terpolymers. ICU.


Zinc Dibutyldithiocarbamate is a widely used active secondary accelerator for dry rubber.
Zinc Dibutyldithiocarbamate can be used as a primary accelerator in latex.
Zinc Dibutyldithiocarbamate is used in NR, SBR, NBR, IIR, EPDM and latex industry.


Zinc Dibutyldithiocarbamate is used Chemical Synthesis, Plastic, Resin & Rubber, Accelerators, Antioxidants, Polymers, Stabilizer.
Zinc Dibutyldithiocarbamate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Zinc Dibutyldithiocarbamate is used in the following products: coating products and adhesives and sealants.
Other release to the environment of Zinc Dibutyldithiocarbamate is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Other release to the environment of Zinc Dibutyldithiocarbamate is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Zinc Dibutyldithiocarbamate can be found in products with material based on: rubber (e.g. tyres, shoes, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and wood (e.g. floors, furniture, toys).
Zinc Dibutyldithiocarbamate is used in the following products: coating products.


Zinc Dibutyldithiocarbamate is used in the following areas: building & construction work.
Zinc Dibutyldithiocarbamate is used for the manufacture of: furniture.
Other release to the environment of Zinc Dibutyldithiocarbamate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.


Zinc Dibutyldithiocarbamate is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.
Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: formulation of mixtures and formulation in materials.


Zinc Dibutyldithiocarbamate is used in the following products: adhesives and sealants, coating products and fillers, putties, plasters, modelling clay.
Zinc Dibutyldithiocarbamate is used in the following areas: building & construction work.
Zinc Dibutyldithiocarbamate is used for the manufacture of: rubber products, textile, leather or fur and machinery and vehicles.


Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: in processing aids at industrial sites, as processing aid and in the production of articles.
Release to the environment of Zinc Dibutyldithiocarbamate can occur from industrial use: manufacturing of the substance.



WHAT IS ZINC DIBUTYLDITHIOCARBAMATE AND WHERE IS ZINC DIBUTYLDITHIOCARBAMATE FOUND?
Zinc Dibutyldithiocarbamateis used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.
Zinc Dibutyldithiocarbamate is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of Zinc Dibutyldithiocarbamate.



ALTERNATIVE PARENTS OF ZINC DIBUTYLDITHIOCARBAMATE:
*Organosulfur compounds
*Organopnictogen compounds
*Organonitrogen compounds
*Hydrocarbon derivatives



SUBSTITUENTS OF ZINC DIBUTYLDITHIOCARBAMATE:
*Organic transition metal salt
*Organic nitrogen compound
*Organopnictogen compound
*Hydrocarbon derivative
*Organosulfur compound
*Organonitrogen compound
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIBUTYLDITHIOCARBAMATE:
Physical State: Powder
Color: White, off-white
Odor: Not available
Melting Point/Freezing Point:
Melting point/range: 104 - 108 °C
Initial Boiling Point and Boiling Range: 318 °C at 1.013 hPa
Flammability (Solid, Gas): Not available
Upper/Lower Flammability or Explosive Limits: Not available
Flash Point: Not available
Autoignition Temperature: Not available
Decomposition Temperature: Not available
pH: Not available
Viscosity:
Kinematic viscosity: Not available;
Dynamic viscosity: Not available
Water Solubility: 0.1 g/l at 25 °C - Insoluble
Partition Coefficient n-Octanol/Water (log Pow): 2.16 at 25 °C

Vapor Pressure: < 0.1 hPa at 25 °C
Density: 1.24 g/cm3 at 20 °C
Relative Density: Not available
Relative Vapor Density: Not available
Particle Characteristics: Not available
Explosive Properties: Not available
Oxidizing Properties: None
Other Safety Information: Not available
Molecular Weight: 474.1 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 12
Exact Mass: 472.105276 g/mol
Monoisotopic Mass: 472.105276 g/mol
Topological Polar Surface Area: 72.7 Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 112

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Compound Formula: C18H36N2S4Zn
Molecular Weight: 474.12 g/mol
Appearance: White to very pale yellow powder or crystals
Melting Point: 109°C
Boiling Point: Not applicable (N/A)
Density: Not applicable (N/A)
Solubility in H2O: Insoluble
Exact Mass: 472.105 g/mol
Monoisotopic Mass: 472.105 g/mol
Linear Formula: C18H36N2S4Zn

MDL Number: MFCD00067274
EC Number: 205-232-8
PubChem CID: 5284483
IUPAC Name: Zinc; N,N-dibutylcarbamodithioate
SMILES: CCCCNC(CCCC)C(=S)[S-].CCCCNC(CCCC)C(=S)[S-].[Zn+2]
InChI Identifier: InChI=1S/2C9H19NS2.Zn/c21-3-5-7-10(9(11)12)8-6-4-2;/h23-8H2,1-2H3,(H,11,12);/q;;+2/p-2
InChI Key: BOXSVZNGTQTENJ-UHFFFAOYSA-L
Melting Point: 109°C
Color: White-Yellow
Quantity: 25 g
UN Number: 3077
Formula Weight: 474.12
Percent Purity: ≥98.0% (T)
Physical Form: Crystalline Powder

Chemical Name or Material: Zinc(II) Dibutyldithiocarbamate
Appearance: White powder (estimated)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 104.00 °C @ 760.00 mm Hg (estimated)
Flash Point: 32.00 °F TCC (0.00 °C) (estimated)
CAS registration number: 136-23-2
Unique Ingredient Identifier: HNM5J934VP
Molecular formula: 2C9H18NS2.Zn
International Chemical Identifier (InChI): BOXSVZNGTQTENJ-UHFFFAOYSA-L
SMILES: C([S-])(=S)N(CCCC)CCCC.[Zn+2].C([S-])(=S)N(CCCC)CCCC
Formula: C18H36N2S4Zn
InChI: InChI=1S/2C9H19NS2.Zn/c21-3-5-7-10(9(11)12)8-6-4-2;/h23-8H2,1-2H3,(H,11,12);/q;;+4/p-2

InChIKey: UTKYIUWPTCDQSS-UHFFFAOYSA-L
Molecular Weight: 474.122 g/mol
SMILES: C(N(CCCC)C=1S[Zn]2(SC(N(CCCC)CCCC)=[S+]2)[S+]1)CCC
SPLASH: splash10-05fu-9610500000-14d9eea215477cd6b163
Source of Spectrum: JZ-1992-3347-0
Wiley ID: 1393219
Chemical Formula: C18H36N2S4Zn
Average Molecular Mass: 474.120 g/mol
Monoisotopic Mass: 472.105 g/mol
CAS Registry Number: 136-23-2
IUPAC Name: zinc(2+) ion bis((dibutylcarbamothioyl)sulfanide)
Traditional Name: zinc(2+) ion bis((dibutylcarbamothioyl)sulfanide)
SMILES Representation: [Zn++].CCCCN(CCCC)C([S-])=S.CCCCN(CCCC)C([S-])=S
InChI Identifier: InChI=1S/2C9H19NS2.Zn/c21-3-5-7-10(9(11)12)8-6-4-2;/h23-8H2,1-2H3,(H,11,12);/q;;+2/p-2
InChI Key: BOXSVZNGTQTENJ-UHFFFAOYSA-L



FIRST AID MEASURES of ZINC DIBUTYLDITHIOCARBAMATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIBUTYLDITHIOCARBAMATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC DIBUTYLDITHIOCARBAMATE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIBUTYLDITHIOCARBAMATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIBUTYLDITHIOCARBAMATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ZINC DIBUTYLDITHIOCARBAMATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC DIBUTYLDITHIOCARBAMATE
Zinc dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc dibutyldithiocarbamate has a role as an antifungal agrochemical.
Zinc dibutyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.

CAS: 136-23-2
MF: C18H36N2S4Zn
MW: 474.14
EINECS: 205-232-8

Synonyms
(dibutyldithiocarbamato)zinc(ii);accelbz;acetozdbd;bis(dibutylcarbamodithioato-S,S’)-,(T-4)-Zinc;vulkacitldb/c;zimate,butyl;zincbibutyldithiocarbamate;Zinc N,N-dibutyldithiocarbamate
Zinc dibutyldithiocarbamate;(Dibutyldithiocarbamato)zinc(II) ; AI3-14880 ; Accel BZ ; Aceto ZDBD ; Bis(N,N-dibutyldithiocarbamato)zinc ; Butazate ; Butazate 50-D ; Butyl zimate ; Butyl ziram ; Carbamic acid, dibutyldithio-, zinc complex ; Carbamodithioic acid, dibutyl-, zinc salt ; Dibutyldithiocarbamic acid zinc salt ; EINECS 205-232-8 ; HSDB 2906 ; NSC 36548 ; NSC 3880 ; Nocceler BZ ; Soxinol BZ ; USAF GY-5 ; Vulcacure ; Vulcacure ZB ; Vulkacit LDB ; Vulkacit ldb/C ; Zimate, butyl ; Zinc N,N-dibutyldithiocarbamate ; Zinc bibutyldithiocarbamate ; Zinc bis(dibutyldithiocarbamate) ; Zinc dibutyldithiocarbamate ; Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)- ; (T-4)-Bis(dibutylcarbamodithioato-S,S')zinc ; Zinc, bis(dibutylcarbamodithioato-S,S')-, (beta-4)- ; Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)- ; Zinc, bis(dibutyldithiocarbamato)-;136-23-2;Zinc(II) Dibutyldithiocarbamate;Zinc bis(dibutyldithiocarbamate);zinc;N,N-dibutylcarbamodithioate;DTXSID0021462;Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-;DTXCID501462;Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-;CAS-136-23-2;Bis(dibutyldithiocarbamato)zinc;zinc bis(dibutylcarbamodithioate);HNM5J934VP;SCHEMBL35745;dibutyldithiocarbamate zinc salt;ZINCDIBUTYLDITHIOCARBAMATE;CHEMBL2373108;CHEBI:144323;NSC-3880;Tox21_113038;Tox21_202601;NSC-36548;AKOS015839728;zinc bis(dibutylthiocarbamoyl)disulfide;zinc bis(dibutyldithiocarbamoyl)disulfide;Dibutyldithiocarbamic Acid Zinc(II) Salt;NCGC00188440-01;NCGC00260149-01;zinc bis(dibutyldithiocarbamoyl)disulphide;ZINC DIBUTYLDITHIOCARBAMATE [INCI];CS-0152117;D0227;FT-0689157;NS00079390;E81950;ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-;ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB];(T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc;Q27280015

Zinc dibutyldithiocarbamate contains a dibutyldithiocarbamate and a zinc(2+).
Zinc dibutyldithiocarbamate is functionally related to a dibutyldithiocarbamic acid.
White powder; pleasant odor.
Soluble in carbon disulfide, benzene, and chloroform; insoluble in water.
A rubber chemical, used as a vulcanization accelerator.
Zinc dibutyldithiocarbamate can also be contained in paints, glue removers, and anticorrosive.
Zinc dibutyldithiocarbamate was contained in “carba-mix.”
Zinc dibutyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.

Zinc dibutyldithiocarbamate has a role as an antifungal agrochemical.
Zinc dibutyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc dibutyldithiocarbamate contains a dibutyldithiocarbamate and a zinc(2+).
Zinc dibutyldithiocarbamate is functionally related to a dibutyldithiocarbamic acid.
Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen.
Sensitivity to Zinc dibutyldithiocarbamate may be identified with a clinical patch test.
Zinc dibutyldithiocarbamate is a chemical compound that forms a complex with fatty acids.
Zinc dibutyldithiocarbamate is used as an absorbent and sample preparation agent in uv spectroscopy.

Zinc dibutyldithiocarbamate can also cause allergic reactions and is toxic to cells in the presence of calcium stearate.
This chemical is found in reaction solutions, where Zinc dibutyldithiocarbamate reacts with hydrochloric acid and boron nitride to form zinc diethyldithiocarbamate.
Zinc dibutyldithiocarbamate has shown growth factor-like properties and was shown to enhance the rate of cell growth on V79 cells when combined with polyene.

Zinc dibutyldithiocarbamate exhibits versatile applications within various fields.
Zinc dibutyldithiocarbamate is particularly useful within the pharmaceutical industry wherein it acts as a catalyst for synthesizing active pharmaceutical ingredients.
Within the polymers industry and rubber manufacturing, Zinc dibutyldithiocarbamate accelerates the production process offering high-quality end-products.
Additionally, Zinc dibutyldithiocarbamate finds usage within miscellaneous chemical syntheses and for industrial applications such as wastewater treatment and gas purification.
Zinc dibutyldithiocarbamate is a chemical compound that is widely used in various industries, including medical, environmental, and industrial research.
Zinc dibutyldithiocarbamate is a white to yellowish powder that is soluble in organic solvents and insoluble in water.
Zinc dibutyldithiocarbamate is a member of the dithiocarbamate family, which is known for its diverse biological activities.
The relative density is 1.18~1.24, and the melting point is above 102 ℃.
Soluble in benzene, carbon disulfide, chloroform, dichloromethane, slightly soluble in gasoline, insoluble in water and dilute alkali.

Zinc dibutyldithiocarbamate Chemical Properties
Melting point: 104-110°C
Boiling point: 318℃[at 101 325 Pa]
Density: 1,21 g/cm3
Vapor pressure: 0Pa at 25℃
Storage temp.: Inert atmosphere,Room Temperature
Solubility: Insoluble in water
Form: solid
Specific Gravity: 1.21
Color: White
Odor: wh. powd., pleasant odor
Water Solubility: 100μg/L at 25℃
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChIKey: BOXSVZNGTQTENJ-UHFFFAOYSA-L
LogP: 2.16 at 25℃
CAS DataBase Reference: 136-23-2(CAS DataBase Reference)
EPA Substance Registry System: Zinc dibutyldithiocarbamate (136-23-2)

Uses
Accelerator for latex dispersions and cements, etc; ultra-accelerator for lubricating oil additive.
Zinc dibutyldithiocarbamate is a rubber chemical used as a vulcanization accelerator.
Zinc dibutyldithiocarbamate can also be found in paints, glue removers and anticorrosives.
Zinc dibutyldithiocarbamate was contained in the "carba-mix".
Zinc dibutyldithiocarbamate is used as activator; antidegradant; accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethyJene-propylene-diene terpolymers.

Preparation
Accelerator bz is prepared by reacting an aqueous solution of an alkali metal salt of di-n-butyl dithiocarbamic acid with an aqueous solution of a water-soluble zinc salt.
Zinc dibutyldithiocarbamate is a vulcanization accelerator for natural rubber and latex.
ZINC DIBUTYLDITHIOCARBAMATE (ZDBC)

Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate (ZDBC) has a role as an antifungal agrochemical.
Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt and a zinc molecular entity.


CAS Number: 136-23-2
EC Number: 205-232-8
MDL number: MFCD00067274
Molecular Formula: C18H36N2S4Zn


Zinc Dibutyldithiocarbamate (ZDBC) (CAS# 136-23-2) is a useful research chemical compound.
Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt that is the zinc salt of dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate (ZDBC) has a role as an antifungal agrochemical.


Zinc Dibutyldithiocarbamate (ZDBC) is a dithiocarbamate salt and a zinc molecular entity.
Zinc Dibutyldithiocarbamate (ZDBC) contains a dibutyldithiocarbamate and a zinc(2+).
Zinc Dibutyldithiocarbamate (ZDBC) is functionally related to a dibutyldithiocarbamic acid.


Zinc Dibutyldithiocarbamate (ZDBC) is a dermatological sensitizer and allergen.
Sensitivity to Zinc Dibutyldithiocarbamate (ZDBC) may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate (ZDBC) is a Standardized Chemical Allergen.


The physiologic effect of Zinc Dibutyldithiocarbamate (ZDBC) is by means of Increased Histamine Release, and Cell-mediated Immunity.
Zinc Dibutyldithiocarbamate (ZDBC) will prevulcanise latex; gives high modulus and transparency.
Zinc Dibutyldithiocarbamate (ZDBC) has high solubility in rubbers.


Zinc Dibutyldithiocarbamate (ZDBC) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Zinc Dibutyldithiocarbamate (ZDBC) is one of numerous organometallic compounds manufactured by American Elements under the trade name AE Organometallics.


Zinc Dibutyldithiocarbamate (ZDBC) contains a dibutyldithiocarbamate and a zinc(2+).
Zinc Dibutyldithiocarbamate (ZDBC) is functionally related to a dibutyldithiocarbamic acid.
Zinc Dibutyldithiocarbamate (ZDBC) is nonflammable.


Zinc Dibutyldithiocarbamate (ZDBC) is a rubber chemical used as a vulcanization accelerator.
Zinc Dibutyldithiocarbamate (ZDBC) can also be found in paints, glue removers and anticorrosives.
Zinc Dibutyldithiocarbamate (ZDBC) was contained in the "carba-mix".


Zinc Dibutyldithiocarbamate (ZDBC) is white solid with a pleasant odor.
Zinc Dibutyldithiocarbamate (ZDBC) is white to cream-colored powder.
Zinc Dibutyldithiocarbamate (ZDBC) is a dermatological sensitizer and allergen.


Sensitivity to Zinc Dibutyldithiocarbamate (ZDBC) may be identified with a clinical patch test.
Zinc Dibutyldithiocarbamate (ZDBC) is a dermatological sensitizer and allergen and its formula is C18H36N2S4Zn.
Rubber Accelerator Zinc Dibutyldithiocarbamate (ZDBC) is also known as BZ , White powder(granule).


Zinc Dibutyldithiocarbamate (ZDBC)'s Density is 1.24, soluble in carbon disulfide, benzene, chloroform, ethanol, ether, insoluble in water and dilute alkali.
Zinc Dibutyldithiocarbamate (ZDBC) is stable storage.



USES and APPLICATIONS of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
Zinc Dibutyldithiocarbamate (ZDBC) is used safe-processing secondary accelerator.
Zinc Dibutyldithiocarbamate (ZDBC) can be used as primary in latex.
Zinc Dibutyldithiocarbamate (ZDBC) is used high resistance to hydrolysis; low solubility in rubbers.


Zinc Dibutyldithiocarbamate (ZDBC) is recognized to have low nitrosamine potential.
Zinc Dibutyldithiocarbamate (ZDBC) is used in sheeting, extrusions and latex.
Zinc Dibutyldithiocarbamate (ZDBC) is used in NR, IIR, SBR, and EPDM


Zinc Dibutyldithiocarbamate (ZDBC) is a fast primary or secondary accelerator for NR, SBR, IIR, EPDM and for natural and synthetic latexes mainly in transparent goods and in prevulcanized latex.
Zinc Dibutyldithiocarbamate (ZDBC) is also used as an antioxidant in rubber-based adhesive systems and as a stabilizer in cement.


Zinc Dibutyldithiocarbamate (ZDBC) is used in NR 1 or 2 super accelerator.
IR, BR, SBR, NBR, HR EPDM and Zinc Dibutyldithiocarbamate (ZDBC)'s latex.
Properties are similar to PZ and EZ.


Drying rubber is less effective than PZ and EZ.
Effectively Zinc Dibutyldithiocarbamate (ZDBC) is used in natural and synthetic latex, faster curing and less frosting at room temperature (low temperature) than PZ and EZ.


Zinc Dibutyldithiocarbamate (ZDBC) is a widely used active secondary accelerator for dry rubber.
Zinc Dibutyldithiocarbamate (ZDBC) can be used as a primary accelerator in latex.
Zinc Dibutyldithiocarbamate (ZDBC) is used in NR, SBR, NBR, IIR, EPDM and latex industry.


Zinc Dibutyldithiocarbamate (ZDBC) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: coating products and adhesives and sealants.


Other release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) is likely to occur from: indoor use as processing aid and outdoor use as processing aid.
Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Other release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Zinc Dibutyldithiocarbamate (ZDBC) can be found in products with material based on: rubber (e.g. tyres, shoes, toys), plastic (e.g. food packaging and storage, toys, mobile phones) and wood (e.g. floors, furniture, toys).
Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: coating products.


Zinc Dibutyldithiocarbamate (ZDBC) is used in the following areas: building & construction work.
Zinc Dibutyldithiocarbamate (ZDBC) is used for the manufacture of: furniture.
Other release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use as processing aid.


Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: coating products, fillers, putties, plasters, modelling clay, polymers and adhesives and sealants.
Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: formulation of mixtures and formulation in materials.


Zinc Dibutyldithiocarbamate (ZDBC) is used in the following products: adhesives and sealants, coating products and fillers, putties, plasters, modelling clay.
Zinc Dibutyldithiocarbamate (ZDBC) is used in the following areas: building & construction work.


Zinc Dibutyldithiocarbamate (ZDBC) is used for the manufacture of: rubber products, textile, leather or fur and machinery and vehicles.
Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: in processing aids at industrial sites, as processing aid and in the production of articles.


Release to the environment of Zinc Dibutyldithiocarbamate (ZDBC) can occur from industrial use: manufacturing of the substance.
Zinc Dibutyldithiocarbamate (ZDBC) is used chemical Synthesis, Plastic, Resin & Rubber, Accelerators, Antioxidants, Polymers, Stabilizer.
Zinc Dibutyldithiocarbamate (ZDBC) is used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.


Zinc Dibutyldithiocarbamate (ZDBC) is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of Zinc Dibutyldithiocarbamate (ZDBC).
Zinc Dibutyldithiocarbamate (ZDBC) is a rubber accelerator for natural and synthetic rubber and latex.


Zinc Dibutyldithiocarbamate (ZDBC) can be used up to 1.50 PHR without bloom.
Zinc Dibutyldithiocarbamate (ZDBC) Dispersion is characterised as a fast curing accelerator for use in both Natural and Synthetic latex compounding, with loading levels for sole use being typically 1.0-1.5 parts per hundred dry rubber.


Recommend for use in translucent latex articles and compounds requiring lower modulus than that achieved with ZDEC.
More commonly used in conjuction with ZDEC to form synergtically boosted and more efficient accelerator systems, with the loading level for Zinc Dibutyldithiocarbamate (ZDBC) being usually lower (0.30-0.60phr) than that of the ZDEC (0.4-1.0phr).


Zinc Dibutyldithiocarbamate (ZDBC) is a vulcanization accelerator for natural rubber and latex and a stabilizer for rubber-based adhesive systems, isobutylene-isoprene copolymers and polypropylene.
Zinc Dibutyldithiocarbamate (ZDBC) is used in a number of rubber and rubber-based materials for food packaging and food handling, e.g. conveyor belts.


Zinc Dibutyldithiocarbamate (ZDBC) is contact allergens that cross-react in some individuals.
Zinc Dibutyldithiocarbamate (ZDBC), like many low-molecular-weight contact allergens, can only trigger an immune response when bound to a protein in the form of an immunogenic protein–hapten complex.


Zinc Dibutyldithiocarbamate (ZDBC) is used Accelerator for latex dispersions and cements, etc; ultra-accelerator for lubricating oil additive.
Zinc Dibutyldithiocarbamate (ZDBC) is used as activator; antidegradant; accelerator for natural rubber, butadiene, styrene-butadiene, nitrile-butadiene, butyl rubber, and ethyJene-propylene-diene terpolymers.


Zinc Dibutyldithiocarbamate (ZDBC) is used as accelerator (rubber vulcanization, latex dispersions, and cements), ultra-accelerator for lubricating oil additives, and stabilizer in food packaging and handling.
Zinc Dibutyldithiocarbamate (ZDBC) provides fast cures at low temperatures; slower cure rates than with EZ (ZDEC) or MZ (ZDMC).



PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
White powder (granule).
The density of Zinc Dibutyldithiocarbamate (ZDBC) is 1.24.
Zinc Dibutyldithiocarbamate (ZDBC) is soluble in CS2 benzene, chloroform, alcohol, diethyl ether.
Zinc Dibutyldithiocarbamate (ZDBC) is iinsoluble in water and low concentration alkali.
Zinc Dibutyldithiocarbamate (ZDBC) is good storage stability.



CHEMICAL PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
Zinc Dibutyldithiocarbamate (ZDBC) is white powder.
Zinc Dibutyldithiocarbamate (ZDBC) has pleasant odor.
Zinc Dibutyldithiocarbamate (ZDBC) is soluble in carbon disulfide, benzene, and chloroform.
Zinc Dibutyldithiocarbamate (ZDBC) is insoluble in water.



PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
*Specific gravity:1.30.
*High resistance to hydrolysis;
*Low solubility in rubbers.
*Fast at higher vulca nisation temperatures.



PROPERTIES OF ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
White, pale yellow or offwhite powder, melting point: >103 ºC, density: 1.24, solubility: freely soluble in carbon disulfide, carbon tetrachloride, dichloromethane, benzene, chloroform, soluble in acetone, ethyl acetate, insoluble in water.



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
Molecular Weight: 474.1 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 12
Exact Mass:472.105276 g/mol
Monoisotopic Mass: 472.105276 g/mol
Topological Polar Surface Area: 72.7Ų
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 112
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Physical state: powder
Color: white, off-white
Odor: No data available
Melting point/freezing point:
Melting point/range: 104 - 108 °C
Initial boiling point and boiling range: 318 °C at 1.013 hPa
Flammability (solid, gas): The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility 0,1 g/l at 25 °C
Partition coefficient: n-octanol/water:
log Pow: 2,16 at 25 °C
Bioaccumulation is not expected.
Vapor pressure: < 0,1 hPa at 25 °C
Density: 1,24 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Melting point: 104-110°C
Boiling point: 318℃[at 101 325 Pa]
Density: 1,21 g/cm3
vapor pressure: 0 Pa at 25℃
storage temp.: Inert atmosphere,Room Temperature
solubility: Insoluble in water
form: solid
Specific Gravity: 1.21
color: White
Odor: wh. powd., pleasant odor
Water Solubility: 100μg/L at 25℃
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions
InChIKey: BOXSVZNGTQTENJ-UHFFFAOYSA-L
LogP: 2.16 at 25℃
CAS Number: 136-23-2
Molecular Formula: C₁₈H₃₆N₂S₄Zn
Appearance: White to Off-White Solid
Melting Point: 107 - 109°C
Molecular Weight: 474.12
Storage: 4°C, Inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly, Sonicated)

Compound Formula: C18H36N2S4Zn
Molecular Weight: 474.12
Appearance: White to very pale yellow powder or crystals
Melting Point: 109 °C
Boiling Point: N/A
Density: N/A
Solubility in H2O: Insoluble
Exact Mass: 472.105 g/mol
Monoisotopic Mass: 472.105 g/mol
Linear Formula: C18H36N2S4Zn
MDL Number: MFCD00067274
EC No.: 205-232-8
Pubchem CID: 5284483
IUPAC Name: zinc; N,N-dibutylcarbamodithioate
SMILES: CCCCN(CCCC)C(=S)[S-].CCCCN(CCCC)C(=S)[S-].[Zn+2]
InchI Identifier: InChI=1S/2C9H19NS2.Zn/c2*1-3-5-7-10(9(11)12)8-6-4-2;/h2*3-8H2,1-2H3,(H,11,12);/q;;+2/p-2
InchI Key: BOXSVZNGTQTENJ-UHFFFAOYSA-L



FIRST AID MEASURES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC DIBUTYLDITHIOCARBAMATE (ZDBC):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
Zinc dibutyldithiocarbamate
136-23-2
Zinc(II) Dibutyldithiocarbamate
Zinc bis(dibutyldithiocarbamate)
zinc;N,N-dibutylcarbamodithioate
Bis(dibutyldithiocarbamato)zinc
DTXSID0021462
Vulcacure
Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-, (T-4)-
DTXCID501462
Zinc, bis(dibutylcarbamodithioato-.kappa.S,.kappa.S')-, (T-4)-
CAS-136-23-2
Butazate
C18H36N2S4Zn
Butyl zimate
Butyl ziram
Vulcacure ZB
Zimate, butyl
Nocceler BZ
Vulkacit ldb/C
zinc bis(dibutylcarbamodithioate)
Soxinol BZ
Vulkacit LDB
Accel BZ
Aceto ZDBD
Butazate 50-D
ZDBC
Zinc bibutyldithiocarbamate
UNII-HNM5J934VP
USAF GY-5
Zinc dibutyl dithiocarbamate
HNM5J934VP
SCHEMBL35745
dibutyldithiocarbamate zinc salt
Zinc N,N-dibutyldithiocarbamate
ZINCDIBUTYLDITHIOCARBAMATE
CHEMBL2373108
(Dibutyldithiocarbamato)zinc(II)
HSDB 2906
CHEBI:144323
Zinc, bis-(dibutyldithiocarbamate)
Bis(N,N-dibutyldithiocarbamato)zinc
Dibutyldithiocarbamic acid zinc salt
NSC 3880
NSC-3880
EINECS 205-232-8
Tox21_113038
Tox21_202601
NSC 36548
NSC-36548
AKOS015839728
zinc bis(dibutylthiocarbamoyl)disulfide
Bis(dibutyldithiocarbamic acid)zinc salt
zinc bis(dibutyldithiocarbamoyl)disulfide
Dibutyldithiocarbamic Acid Zinc(II) Salt
NCGC00188440-01
NCGC00260149-01
zinc bis(dibutyldithiocarbamoyl)disulphide
Carbamodithioic acid, dibutyl-, zinc salt
ZINC DIBUTYLDITHIOCARBAMATE [INCI]
ZINC, BIS(DIBUTYLDITHIOCARBAMATO)-
AI3-14880
CS-0152117
D0227
FT-0689157
E81950
EC 205-232-8
ZINC, BIS(DIBUTYLCARBAMODITHIOATO-S,S')-
ZINC, BIS(DIBUTYLDITHIOCARBAMATO)- [HSDB]
Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-
(T-4)-bis(dibutylcarbamodithioato-kappaS,kappaS')zinc
Q27280015
Zinc, bis (dibutilcarbamoditioato-kS, KS')-
(T-4)-
di-n-Butyldithiocarbamic acid,zinc salt
Zinc, bis(dibutylcarbamodithioato-S,S')-
(T-4)-
Zinc, bis(dibutyldithiocarbamato)-
Aceto zdbd
Bis(dibutyldithiocarbamato)zinc
Butazate
Butazate 50-D
Butyl zimate
Butyl ziram
Carbamic acid, dibutyldithio-, zinc complex
Dibutyldithiocarbamic acid zinc salt
USAF GY-5
Vulcacure
Vulkacit ldb/C
Zimate, butyl
Zinc bibutyldithiocarbamate
Zinc N,N-dibutyldithiocarbamate
Accelerator BZ powder
Butasan
Butasan vulcanization accelerator
Butazin
Nocceler BZ
Octocure ZDB-50
Perkacit ZDBC
Soxinol BZ
ZBC
Zinc bis(dibutyldithiocarbamate)
Zinc di-n-butyl dithiocarbamate
bis(dibutyldithiocarbamate)zinc(II)
(Dibutyldithiocarbamato)zinc(II)
Accel BZ
Accelerator BZ
Aceto ZDBD
Antioxidant BZ
BZ
BZ 75
BZ-P
Bis(N,N-dibutyldithiocarbamato)zinc
Bis(dibutyldithiocarbamato)zinc
Butazate
Butazate 50D
Butyl Zimate
Butyl Ziram
Zinc N,N-Dibutyldithiocarbamate
Zinc Bis(Dibutyldithiocarbamate)
ZBC
Zinc(II) Dibutyl dithiocarbamate
Zinc bis(dibutyldithiocarbamate)
Zinc N,N-dibutylcarbamodithioate
Dibutyldithiocarbamic Acid Zinc(II) Salt
carbamate-BZ
ZDBC (BZ)
zbc
accelbz
Nsc3880
butazate
usafgy-5
acetozdbd
soxinolbz
vulcacure
butylziram
noccelerbz
(Dibutyldithiocarbamato)zinc(II)
Accel BZ
Aceto ZDBD
Bis(N,N-dibutyldithiocarbamato)zinc
Bis(dibutyldithiocarbamato)zinc
Butazate
Butazate 50-D
Butyl zimate
Butyl ziram
Carbamic acid, dibutyldithio-, zinc complex
Carbamodithioic acid, dibutyl-, zinc salt
Dibutyldithiocarbamic acid zinc salt
Nocceler BZ
Soxinol BZ
Vulcacure
Vulcacure ZB
Vulkacit LDB
Vulkacit LDB/C
Zimate, butyl
Zinc N,N-dibutyldithiocarbamate
Zinc bis(dibutyldithiocarbamate)
Zinc dibutyldithiocarbamate
Zinc, bis(dibutylcarbamodithioato-S,S')-, (T-4)-
Zinc, bis(dibutylcarbamodithioato-kappaS,kappaS')-
(T-4)- Zinc, bis(dibutyldithiocarbamato)-
ZDBC
Zinc bis(dibutyldithiocarbamate)
Dibutyldithiocarbamic acid zinc(II) salt
zinc,N,N-dibutylcarbamodithioate
Zinc(II) dibutyldithiocarbamate
Zinc Dibuthyl Dithiocarbamate
NURsol ZDBC
zinc bis(dibutyldithiocarbamate)
accelerator bz
zincbutyldithiocarbamate
zine dibutyl dithiocarbamate
zinc dibutyl dithiocarbamate
zdbc
(dibutyldithiocarbamato)zinc(ii)
accelbz
acetozdbd
bis(dibutylcarbamodithioato-s,s')-,(t-4)-zinc
bis(dibutyldithiocarbamato)-zin
bis(n,n-dibutyldithiocarbamato)zinc
butazate
butazate50-d
butylziram
dibutyl-carbamodithioicacizincsalt
dibutyldithiocarbamicacidzincsalt
dibutyldithio-carbamicacizinccomplex
noccelerbz;s')-bis(dibutylcarbamodithioato-(beta-4)-zin
s')-bis(dibutylcarbamodithioato-(t-4)-zin
soxinolbz
usafgy-5
vulcacure
vulcacurezb
vulcaurezb
Accelerant BZ
N,N-Copper dibuthyldithiocarbamate
zinc bis(dibutylcarbamodithioate)
ACCELERATOR ZDBC
ACCELERATOR ZDBC(BZ)
(T-4)-bis(dibutylcarbamodithioato-κS,κS')zinc
bis(dibutyldithiocarbamato)zinc
dibutyldithiocarbamate zinc salt
zinc bis(dibutyldithiocarbamate)
zinc bis(dibutyldithiocarbamoyl)disulfide
zinc bis(dibutyldithiocarbamoyl)disulphide
zinc bis(dibutylthiocarbamoyl)disulfide
Butasan
Butazate
Butazin
Butyl Zimate
Butyl Ziram
Nocceler BZ
Soxinol
ZBC
ZDBC
Zinc bis(dibutyldithiocarbamate)
Zinc N, N-dibutyldithiocarbamate
Zinc N,N-dibutyldithiocarbamate
Vulcacure ZB
Di-n-butyldithiocarbamic Acid Zinc Salt
Butasan
Butazate
Butazin
Zinc bis(dibutylcarbamodithioato-S,S')-
Zinc bis(dibutyldithiocarbamate)
Butyl zimate
BZ
ZDBC
ZBC

ZINC DIETHYLDITHIOCARBAMATE
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.
Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.


CAS Number: 14324-55-1
EC Number: 238-270-9
MDL number: MFCD00064798
Linear Formula: [(C2H5)2NCS2]2Zn
Molecular Formula : C10H20N2S4Zn



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DTXCID901463, ICW4708Z8G, CHEMBL3182813, zinc bis(diethylcarbamodithioate), CHEBI:144351, RKQOSDAEEGPRER-UHFFFAOYSA-L, Tox21_200263, AKOS030228292, zinc bis(diethylthiocarbamoyl)disulfide, DIETHYLCARBAMIC ACID, ZINC SALT, NSC-177699, zinc bis(diethyldithiocarbamoyl)disulfide, NCGC00257817-01, zinc bis(diethyldithiocarbamoyl)disulphide, CAS-14324-55-1, D0492, FT-0624885, NS00087819, E75979, DIETHYLDITHIOCARBAMIC ACID ZINC SALT [HSDB],
J-007778, (T-4)-bis(diethylcarbamodithioato-kappaS,kappaS')zinc, Q16295596, Zinc bis(diethyldithiocarbamate), Zinc diethylcarbamodithioate, Diethyldithiocarbamic acid zinc salt, zinc diethyldithiocarbamate, ethyl ziram, zinc bis diethyldithiocarbamate, diethyldithiocarbamic acid zinc salt, zinc n,n-diethylcarbamodithioate, ethyl zimate, unii-icw4708z8g, ditiocarb zinc, zdc, zdec, Diethyldithiocarbamic acid zinc salt, Zinc bis(diethyldithiocarbamate), AKOS015914072, Zinc Diethyldithiocarbamate, Zinc diethyldithiocarbamate, 97%, zinc;N,N-diethylcarbamodithioate, Diethyldithiocarbamic acid zinc salt, Accelerator ez powder, Ancazate et, Bis(diethylcarbamodithioato-s,s') zinc, Bis(diethyldithiocarbamato)zinc, Carbamodithioic acid, diethyl-, zinc salt, Diethyldithiocarbamic acid zinc salt, Etazin, Ethasan, Ethazate, Ethyl cymate, Bis(diethyldithiocarbamato)zinc, Carbamodithioic acid, diethyl-, zinc salt, Diethyldithiocarbamic acid zinc salt, Ethazate, Ethyl Ziram, Ethyl cymate, Ethyl zimate, Ethylzimate, Hermat ZDK, Nocceler EZ, Soxinol EZ, Vulcacure ZE, Vulkacit LDA, Vulkacit ZDK, Zimate, ethyl, Zinc N,N-diethyldithiocarbamate, Zinc bis(diethyldithiocarbamate), Zinc diethylcarbamodithioate, Zinc diethyldithiocarbamate (VAN), Zinc, bis(diethylcarbamodithioato-S,S')-, (T-4)-, Zinc, bis(diethyldithiocarbamato), Zinc, tetrakis(diethylcarbamodithioato)di-, Ethasan, Ethazate, Ethazine, Noceller EZ, Soxinol EZ, ZDC, ZDEC, Zinc,bis(N,N-diethylcarbamodithioato-κS,κS′)-,(T-4)-, Zinc,bis(diethyldithiocarbamato)-, Zinc,bis(diethylcarbamodithioato-S,S′)-,(T-4)-, Zinc,bis(diethylcarbamodithioato-κS,κS′)-,(T-4)-, (T-4)-Bis(N,N-diethylcarbamodithioato-κS,κS′)zinc, Zinc diethyldithiocarbamate, Bis(diethyldithiocarbamato)zinc, Zinc bis(diethyldithiocarbamate), Vulkacit ZDK, Zinc diethylcarbamodithioate, Diethyldithiocarbamic acid zinc salt, Ethazate, Ethyl Ziram, Vulcacure ZE, Ethylzimate, Carbamodithioic acid,diethyl-,zinc salt, Hermat ZDK, Vulkacit LDA, Zinc bis(N,N-diethyldithiocarbamate), Zinc N,N-diethyldithiocarbamate, Nocceler EZ, Soxinol EZ, EZ (carbamate), EZ, Bis(diethyldithiocarbamato)zinc(II), Bis(N,N-diethyldithiocarbamato)zinc, NSC 177699, Sanceler EZ, Vulkazit LDA, Perkacit ZDEC-PDR, Karbamat ETS, Accelerator ZDC, ZDC, Accel EZ, ZDEC, Mercure ZDC, Accelerator EZ, Rhenogran ZDEC 80, Accelerator ZDA, Bostex 561, 136-94-7, 14460-21-0, 15465-13-1, 18445-58-4, 32733-02-1, 39456-86-5, 92481-10-2, 115028-55-2, 120092-57-1, 880359-15-9, 905572-85-2, 2169916-09-8, ZDEC, Accelerator EZ, ZINC DIETHYLDITHIOCARBAMATE, RUBBER ACCELERATOR ZDEC(EZ), ZINC N,N-DIETHYLDITHIOCARBAMATE, DIETHYLDITHIOCARBAMIC ACID ZINC SALT



Zinc diethyldithiocarbamate is a dry powder and Liquid.
Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.


Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.
Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).


Zinc diethyldithiocarbamate derives from a diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is a known chelator for copper and zinc.
Zinc diethyldithiocarbamate also a dermatological sensitizer and allergen.


Sensitivity to Zinc diethyldithiocarbamate may be identified with a clinical patch test.
Zinc diethyldithiocarbamate boasts an impressive purity level of 97%, ensuring optimal performance and reliable results in catalytic processes.
Zinc diethyldithiocarbamate is a white to off-white powder, allowing for easy identification and handling during laboratory procedures.


Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.


Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).
Zinc diethyldithiocarbamate is functionally related to a diethyldithiocarbamic acid.


Zinc diethyldithiocarbamate is an inorganic compound that has been shown to have potent anti-inflammatory and antipyretic properties.
Zinc diethyldithiocarbamate has been used as a chemical inhibitor of phospholipase A2, which is an enzyme involved in the inflammatory process.
Zinc diethyldithiocarbamate also has been shown to be a potent inducer of metallothionein and other proteins that are involved in detoxification processes.


Zinc diethyldithiocarbamate is generally immediately available in most volumes.
Zinc diethyldithiocarbamate is high purity, submicron and nanopowder forms may be considered.
Zinc diethyldithiocarbamate is a chemical compound of zinc.


Zinc is a metallic element with the atomic number 30.
It is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc diethyldithiocarbamate belongs to the class of organic compounds known as organosulfur compounds.
These are organic compounds containing a carbon-sulfur bond.
Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.


Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.
Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.


Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).
Zinc diethyldithiocarbamate is functionally related to a diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is a known chelator for copper and zinc.


Sensitivity to Zinc diethyldithiocarbamate may be identified with a clinical patch test.
Zinc diethyldithiocarbamate is a chemical compound of zinc.
Zinc is a metallic element with the atomic number 30.


It is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc diethyldithiocarbamate is used chelating agent that has been used to mobilize toxic metals from the tissues of humans and experimental animals.
Zinc diethyldithiocarbamate is the main metabolite of DISULFIRAM.
Zinc diethyldithiocarbamate, an organo-metallic compound, has found extensive use in scientific and industrial applications over the years.


Zinc diethyldithiocarbamate presents itself as a white powder, soluble in both water and organic solvents, and exhibits strong metal-chelating properties.
Zinc diethyldithiocarbamate serves as a catalyst and reagent in various laboratory reactions and processes.
Within the realm of scientific research, Zinc diethyldithiocarbamate has been harnessed across diverse applications.


Zinc diethyldithiocarbamate has facilitated the study of metal-catalyzed reactions, enabling the synthesis of novel compounds and offering insights into their properties.
Additionally, Zinc diethyldithiocarbamate has been instrumental in exploring biochemical and physiological processes, including the effects of metals on enzyme and protein activity.


The interaction of Zinc diethyldithiocarbamate with metals leads to the formation of chelate complexes.
These complexes subsequently bind to proteins and enzymes, resulting in the inhibition of their activity.
The metal chelation by Zinc diethyldithiocarbamate also exerts additional effects, such as the inhibition of specific biochemical reactions and the modulation of certain enzyme activities.


Zinc diethyldithiocarbamate is used as a common accelerator to latex.
Zinc diethyldithiocarbamate is used a fast curing primary or secondary effective ultra-accelerator for natural and synthetic latex compounds.



USES and APPLICATIONS of ZINC DIETHYLDITHIOCARBAMATE:
Due to its exceptional catalytic properties, Zinc diethyldithiocarbamate finds extensive use in various industries and research laboratories.
Chemical Research uses of Zinc diethyldithiocarbamate: Zinc diethyldithiocarbamate is widely employed as a catalyst in chemical research, enabling scientists to study and develop new compounds with enhanced efficiency.


Polymerization Reactions of Zinc diethyldithiocarbamate: Zinc diethyldithiocarbamate is also instrumental in polymerization reactions, where it acts as a catalyst, promoting the formation of polymers with desirable properties.
Zinc diethyldithiocarbamate is used as accelerator for rubber and latex vulcanization; as heat stabilizer for polyethylene; as stabilizer for butyl rubber, butadiene, and urethane rubbers; as antifouling agent; as fungicide seed disinfectant;


Zinc diethyldithiocarbamate is used activator and accelerator for natural rubber, styrene-butadiene, nitrile-butadiene, and butyl rubber.
Zinc diethyldithiocarbamate can be used as an organocatalyst for the synthesis of high molecular weight polyurethanes from PEG- and PPG-diol macromonomers for use in biomedical applications.


In comparison to other zinc catalysts, Zinc diethyldithiocarbamate demonstrated outstanding activity in the preparation of polyurethanes because of its tolerance to different organic solvents.
Zinc diethyldithiocarbamate can also be used as: A catalyst for the polymerization of olefin oxides.


A precursor to prepare zinc sulfide semiconductor nanowires, which can be used as building blocks for photonic devices.
Zinc diethyldithiocarbamate has been used as an injection solution for the treatment of infectious diseases such as tuberculosis, leprosy, brucellosis, and malaria.


Zinc diethyldithiocarbamate is also used as a pharmacological agent for the treatment of myocardial infarction.
Zinc diethyldithiocarbamate is used as activator; accelerator for natural rubber, styrene-butadiene, nitrile-butadiene, and butyl rubber.
Zinc diethyldithiocarbamate is used as a common accelerator to latex.


-Pharmaceutical Industry uses of Zinc diethyldithiocarbamate:
Zinc diethyldithiocarbamate serves as a catalyst in pharmaceutical synthesis, facilitating the production of vital drugs and pharmaceutical compounds.
Its efficiency and reliability make Zinc diethyldithiocarbamate an indispensable component in drug manufacturing processes.


-Automotive Sector uses of Zinc diethyldithiocarbamate:
Zinc diethyldithiocarbamate is utilized in the automotive industry as a catalyst for various reactions involved in the production of automotive parts and coatings.
Zinc diethyldithiocarbamate contributes to the development of products with enhanced durability and performance characteristics.



COMPOUND TYPE OF ZINC DIETHYLDITHIOCARBAMATE:
*Amine
*Industrial/Workplace Toxin
*Organic Compound
*Organometallic
*Synthetic Compound
*Zinc Compound



ALTERNATIVE PARENTS OF ZINC DIETHYLDITHIOCARBAMATE:
*Organopnictogen compounds
*Organonitrogen compounds
*Organic salts
*Hydrocarbon derivatives
*Substituents
*Organic nitrogen compound
*Organopnictogen compound
*Hydrocarbon derivative
*Organic salt
*Organosulfur compound
*Organonitrogen compound
*Aliphatic acyclic compound



SAFE STORAGE OF ZINC DIETHYLDITHIOCARBAMATE:
Zinc diethyldithiocarbamate should be stored in a cool, dry place, away from incompatible substances and sources of ignition.



COMPOSITION OF ZINC DIETHYLDITHIOCARBAMATE:
Each molecule of Zinc diethyldithiocarbamate contains zinc at its center, tightly bound to two diethyldithiocarbamate ligands.
This composition offers exceptional stability and promotes efficient catalytic activities.



MOLECULAR FORMULA OF ZINC DIETHYLDITHIOCARBAMATE:
The molecular formula, C10H20N2S4Zn, provides clear insights into the specific arrangement of atoms within Zinc diethyldithiocarbamate, facilitating a comprehensive understanding of its chemical properties.



WHAT IS ZINC DIETHYLDITHIOCARBAMATE AND WHERE IS ZINC DIETHYLDITHIOCARBAMATE FOUND?
Zinc diethyldithiocarbamate is used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.
Zinc diethyldithiocarbamate is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of this chemical.



PHYSICAL and CHEMICAL PROPERTIES of ZINC DIETHYLDITHIOCARBAMATE:
Molecular Weight :361.9 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 4
Exact Mass :359.980075 g/mol
Monoisotopic Mass: 359.980075 g/mol
Topological Polar Surface Area :72.7Ų
Heavy Atom Count :17
Formal Charge: 0
Complexity: 73
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
CAS Number: 14324-55-1
Molecular Weight: 361.93
EC Number: 238-270-9
MDL number: MFCD00064798
Physical state: powder
Color: white
Odor: No data available
Melting point/freezing point:
Melting point/range: 178 - 181 °C - lit.
Initial boiling point and boiling range: 301 °C at 1.013 hPa
Flammability (solid, gas): The product is not flammable. - Flammability (solids)
Upper/lower flammability or explosive limits: No data available
Flash point: No data available

Autoignition temperature: does not ignite
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00106 g/l at 20 °C
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,47 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

CAS: 14324-55-1
Molecular Formula: C10H20N2S4Zn
Molecular Weight (g/mol): 361.904
MDL Number: MFCD00064798
InChI Key: RKQOSDAEEGPRER-UHFFFAOYSA-L
PubChem CID: 26633
IUPAC Name: zinc;N,N-diethylcarbamodithioate
SMILES: CCN(CC)C(=S)[S-].CCN(CC)C(=S)[S-].[Zn+2]
Melting Point: 178°C to 183°C
Color: White
Density: 1.48 g/mL
pH: 7.8
Flash Point: 204°C (400°F)
Odor: Odorless
Linear Formula: Zn[CS2N(CH2CH3)2]2

UN Number: UN3077
Solubility Information: Insoluble in water.
Soluble in benzene carbon disulfide and organic liquids.
Formula Weight: 361.9
Concentration or Composition (by Analyte or Components): Zn 17 to 19.5%
Physical Form: Crystalline
Chemical Name or Material: Zinc diethyldithiocarbamate
Formula: C₅H₁₁NS₂
MW: 361,90 g/mol
Melting Pt: 178…183 °C
Density: 1,48
Flash Pt: 204 °C (400 °F)
Storage Temperature: Ambient
MDL Number: MFCD00064798
CAS Number: 14324-55-1
EINECS: 238-270-9

Molecular Formula / Molecular Weight: C10H20N2S4Zn = 361.90
Physical State (20 deg.C): Solid
CAS RN: 14324-55-1
Reaxys Registry Number: 3717403
PubChem Substance ID: 87567161
MDL Number: MFCD00064798
Compound Formula: C10H20N2S4Zn
Molecular Weight: 361.93
Appearance: solid
Melting Point: N/A
Boiling Point: N/A
Density: N/A
Solubility in H2O: N/A
Exact Mass: N/A
Monoisotopic Mass: 361.948212
Charge: N/A

Linear Formula: [(C2H5)2NCS2]2Zn
MDL Number: MFCD00064798
EC No.: 238-270-9
Beilstein/Reaxys No.: N/A
Pubchem CID: N/A
IUPAC Name: N/A
SMILES: [Zn+2].S=C([S-])N(CC)CC.[S-]C(=S)N(CC)CC
InchI Identifier: InChI=1S/2C5H11NS2.Zn/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InchI Key: RKQOSDAEEGPRER-UHFFFAOYSA-L
CBNumber:CB4176909
Molecular Formula:C10H20N2S4Zn
Molecular Weight:361.93
MDL Number:MFCD00064798
MOL File:136-94-7.mol
Melting point: 178-181 °C(lit.)
FDA 21 CFR: 175.105; 177.2600

Chemical Formula: C10H20N2S4Zn
Average Molecular Mass: 361.948 g/mol
Monoisotopic Mass: 359.980 g/mol
CAS Registry Number: 14324-55-1
IUPAC Name: bis[(diethylcarbamothioyl)sulfanyl]zinc
Traditional Name: bis[(diethylcarbamothioyl)sulfanyl]zinc
SMILES CCN(CC)C(=S)S[Zn]SC(=S)N(CC)CC
InChI Identifier: InChI=1S/2C5H11NS2.Zn/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InChI Key: InChIKey=RKQOSDAEEGPRER-UHFFFAOYSA-L
Water Solubility: 0.035 g/L
logP: 3.92
logP: 3.11
logS: -4
Physiological Charge: 0
Hydrogen Acceptor Count: 0

Hydrogen Donor Count: 0
Polar Surface Area: 6.48 Ų
Rotatable Bond Count: 8
Refractivity: 88.24 m³·mol⁻¹
Polarizability: 34.08 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes
Molecular Weight:361.93
Exact Mass:359.980072
EC Number:238-270-9
UNII:ICW4708Z8G

DSSTox ID:DTXSID5021463
Color/Form:White powder
HScode:29302000
PSA:70.66000
XLogP3:2.31750
Appearance:solid
Density:1.47 g/cm3 @ Temp: 20 °C
Melting Point:172-176 °C
Boiling Point:330.6°C (estimate)
Flash Point:204°(400°F)
Water Solubility:Insoluble in water.
soluble in benzene carbon disulfide and organic liquids.
Vapor Pressure:1.1mmHg at 25°C



FIRST AID MEASURES of ZINC DIETHYLDITHIOCARBAMATE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC DIETHYLDITHIOCARBAMATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC DIETHYLDITHIOCARBAMATE:
-Extinguishing media
*Suitable extinguishing media
Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.
*Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
-Further information
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC DIETHYLDITHIOCARBAMATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC DIETHYLDITHIOCARBAMATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
*Storage class:
Storage class (TRGS 510): 13:
Non Combustible Solids



STABILITY and REACTIVITY of ZINC DIETHYLDITHIOCARBAMATE:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

ZINC DIETHYLDITHIOCARBAMATE
DESCRIPTION:

Zinc diethyldithiocarbamate is a chelating ligand.
Zinc diethyldithiocarbamate is used as a common accelerator to latex.
A fast curing primary or secondary effective ultra-accelerator for natural and synthetic latex compounds.

CAS, 14324-55-1
European Community (EC) Number: 238-270-9
Molecular Formula, C10H20N2S4Zn
Molecular Weight (g/mol), 361.904
IUPAC Name, zinc;N,N-diethylcarbamodithioate


SYNONYMS OF ZINC DIETHYLDITHIOCARBAMATE:
zinc diethyldithiocarbamate, ethyl ziram, zinc bis diethyldithiocarbamate, diethyldithiocarbamic acid zinc salt, zinc n,n-diethylcarbamodithioate, ethyl zimate, unii-icw4708z8g, ditiocarb zinc, zdc, zdec, Bis(diethyldithiocarbamato)zinc; Carbamodithioic acid, diethyl-, zinc salt; Diethyldithiocarbamic acid zinc salt; Ethazate; Ethyl Ziram; Ethyl cymate; Ethyl zimate; Ethylzimate; Hermat ZDK; Nocceler EZ; Soxinol EZ; Vulcacure ZE; Vulkacit LDA; Vulkacit ZDK; Zimate, ethyl; Zinc N,N-diethyldithiocarbamate; Zinc bis(diethyldithiocarbamate); Zinc diethylcarbamodithioate; Zinc diethyldithiocarbamate (VAN); Zinc, bis(diethylcarbamodithioato-S,S')-, (T-4)-; Zinc, bis(diethyldithiocarbamato); Zinc, tetrakis(diethylcarbamodithioato)di-; [ChemIDplus],Ammonium Salt Ditiocarb,Bismuth Salt Ditiocarb,Diethylcarbamodithioic Acid,Diethyldithiocarbamate,Diethyldithiocarbamate, Sodium,Diethyldithiocarbamate, Zinc,Diethyldithiocarbamic Acid,Dithiocarb,Ditiocarb,Ditiocarb Sodium,Ditiocarb, Ammonium Salt,Ditiocarb, Bismuth Salt,Ditiocarb, Lead Salt,Ditiocarb, Potassium Salt,Ditiocarb, Sodium Salt,Ditiocarb, Sodium Salt, Trihydrate,Ditiocarb, Tin(4+) Salt,Ditiocarb, Zinc Salt,Imuthiol,Lead Salt Ditiocarb,Potassium Salt Ditiocarb,Sodium Diethyldithiocarbamate,Sodium Salt Ditiocarb,Sodium, Ditiocarb,Thiocarb,Zinc Diethyldithiocarbamate,Zinc Salt Ditiocarb,Zinc diethyldithiocarbamate,14324-55-1,Ethyl Ziram,Ditiocarb ZINC,Zinc bis(diethyldithiocarbamate),zinc;N,N-diethylcarbamodithioate,136-94-7,Bis(diethyldithiocarbamato)zinc,Zinc N,N-diethyldithiocarbamate,bis(Diethylcarbamothioylthio)zinc,Diethyldithiocarbamic acid zinc salt,ZINCDIETHYLDITHIOCARBAMATE,DTXSID5021463,Ethyl zimate,Ethylzimate,Ethazate,Ethyl cymate,Vulcacure ZE,Nocceler EZ,Soxinol EZ,Vulkacit LDA,Vulkacit ZDK,Hermat ZDK,Zinc diethylcarbamodithioate,ETHYLZIRAM,SCHEMBL48550,Zinc Diethyl Dithio,Carbamate,diethyldithiocarbamate zinc salt,DTXCID901463,ICW4708Z8,CHEMBL3182813,zinc bis(diethylcarbamodithioate),CHEBI:144351,RKQOSDAEEGPRER-UHFFFAOYSA-L,Tox21_200263,AKOS030228292,zinc bis(diethylthiocarbamoyl)disulfide,DIETHYLCARBAMIC ACID, ZINC SALT,NSC-177699,zinc bis(diethyldithiocarbamoyl)disulfide,NCGC00257817-01,zinc bis(diethyldithiocarbamoyl)disulphide,CAS-14324-55-1,D0492,FT-0624885,NS00087819,E75979,DIETHYLDITHIOCARBAMIC ACID ZINC SALT [HSDB],J-007778,(T-4)-bis(diethylcarbamodithioato-kappaS,kappaS')zinc,Q16295596



Zinc diethyldithiocarbamate is a dithiocarbamate salt that is the zinc salt of diethyldithiocarbamic acid.
Zinc diethyldithiocarbamate is an accelerator and activator for natural rubber.
Zinc diethyldithiocarbamate has a role as an antifungal agrochemical.

Zinc diethyldithiocarbamate is a dithiocarbamate salt and a zinc molecular entity.
Zinc diethyldithiocarbamate contains a diethyldithiocarbamate and a zinc(2+).
Zinc diethyldithiocarbamate is functionally related to a diethyldithiocarbamic acid.


Ditiocarb zinc, also known as Diethyldithiocarbamic acid zinc salt, is a known chelator for copper and zinc.
Zinc diethyldithiocarbamate also a dermatological sensitizer and allergen.
Sensitivity to ditiocarb zinc may be identified with a clinical patch test.

Zinc diethyldithiocarbamate is a Standardized Chemical Allergen.
The physiologic effect of zinc diethyldithiocarbamate is by means of Increased Histamine Release, and Cell-mediated Immunity.
The chemical classification of zinc diethyldithiocarbamate is Allergens.


Zinc diethyldithiocarbamate (ZDDC), an organo-metallic compound, has found extensive use in scientific and industrial applications over the years.
Zinc diethyldithiocarbamate presents itself as a white powder, soluble in both water and organic solvents, and exhibits strong metal-chelating properties.
ZDDC serves as a catalyst and reagent in various laboratory reactions and processes.


Within the realm of scientific research, Zinc diethyldithiocarbamate has been harnessed across diverse applications.
Zinc diethyldithiocarbamate has facilitated the study of metal-catalyzed reactions, enabling the synthesis of novel compounds and offering insights into their properties.
Additionally, ZDDC has been instrumental in exploring biochemical and physiological processes, including the effects of metals on enzyme and protein activity.

The interaction of Zinc diethyldithiocarbamate with metals leads to the formation of chelate complexes.
These complexes subsequently bind to proteins and enzymes, resulting in the inhibition of their activity.
The metal chelation by ZDDC also exerts additional effects, such as the inhibition of specific biochemical reactions and the modulation of certain enzyme activities.




APPLICATIONS OF ZINC DIETHYLDITHIOCARBAMATE:
Zinc diethyldithiocarbamate (Zn(S2CNEt2)2, ZDTC) can be used as an organocatalyst for the synthesis of high molecular weight polyurethanes from PEG- and PPG-diol macromonomers for use in biomedical applications.
In comparison to other zinc catalysts, ZDTC demonstrated outstanding activity in the preparation of polyurethanes because of its tolerance to different organic solvents.

It can also be used as:

A catalyst for the polymerization of olefin oxides.
A precursor to prepare zinc sulfide semiconductor nanowires, which can be used as building blocks for photonic devices.


Zinc diethyldithiocarbamate is used as an activator and accelerator in natural and butyl rubber as well as in natural and synthetic latexes.
Zinc diethyldithiocarbamate is also used in rubber-based adhesive systems and as a stabilizer in cement.
Further research may identify additional product or industrial usages of this chemical.


Zinc diethyldithiocarbamate is found in rubber.
Zinc diethyldithiocarbamate is used to accelerate the production of rubber.

Zinc diethyldithiocarbamate (Zn(S2CNEt2)2, ZDTC) can be used as an organocatalyst for the synthesis of high molecular weight polyurethanes from PEG- and PPG-diol macromonomers for use in biomedical applications.

In comparison to other zinc catalysts, Zinc diethyldithiocarbamate demonstrated outstanding activity in the preparation of polyurethanes because of its tolerance to different organic solvents.
Zinc diethyldithiocarbamate can also be used as: A catalyst for the polymerization of olefin oxides.
A precursor to prepare zinc sulfide semiconductor nanowires, which can be used as building blocks for photonic devices.

Zinc diethyldithiocarbamate is an inorganic compound that has been shown to have potent anti-inflammatory and antipyretic properties.
Zinc diethyldithiocarbamate has been used as a chemical inhibitor of phospholipase A2, which is an enzyme involved in the inflammatory process.
Zinc diethyldithiocarbamate also has been shown to be a potent inducer of metallothionein and other proteins that are involved in detoxification processes.

Zinc diethyldithiocarbamate has been used as an injection solution for the treatment of infectious diseases such as tuberculosis, leprosy, brucellosis, and malaria.
Zinc diethyldithiocarbamate is also used as a pharmacological agent for the treatment of myocardial infarction.




CHEMICAL AND PHYSICAL PROPERTIES OF ZINC DIETHYLDITHIOCARBAMATE:
Melting Point, 178°C to 183°C
Color, White
Density, 1.48 g/mL
pH, 7.8
Flash Point, 204°C (400°F)
Odor, Odorless
Linear Formula, Zn[CS2N(CH2CH3)2]2
Quantity, 2 kg
UN Number, UN3077
Solubility Information, Insoluble in water. Soluble in benzene carbon disulfide and organic liquids.
CAS, 14324-55-1
European Community (EC) Number: 238-270-9
Molecular Formula, C10H20N2S4Zn
Molecular Weight (g/mol), 361.904
IUPAC Name, zinc;N,N-diethylcarbamodithioate
Molecular Weight
361.9 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
0
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
359.980075 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
359.980075 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
72.7Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
17
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
73
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
3
Computed by PubChem
Compound Is Canonicalized
Yes
Quality Level
100
Assay
97%
reaction suitability
core: zinc
reagent type: catalyst

mp
178-181 °C (lit.)
SMILES string
CCN(CC)C(=S)S[Zn]SC(=S)N(CC)CC
InChI
1S/2C5H11NS2.Zn/c2*1-3-6(4-2)5(7)8;/h2*3-4H2,1-2H3,(H,7,8);/q;;+2/p-2
InChI key
RKQOSDAEEGPRER-UHFFFAOYSA-L
Physical State :
Solid
Storage :
Store at room temperature
Melting Point :
178-181° C (lit.)
Boiling Point :
301° C
Product Number, D0492
Purity / Analysis Method, >99.0%(T)
Molecular Formula / Molecular Weight, C10H20N2S4Zn = 361.90
Physical State (20 deg.C), Solid
CAS RN, 14324-55-1
Reaxys Registry Number, 3717403
PubChem Substance ID, 87567161
MDL Number, MFCD00064798
Appearance, White to Almost white powder to crystal
Purity(Chelometric Titration), min. 99.0 %
Melting point, 178.0 to 182.0 °C
Properties (reference)
Melting Point, 181 °C
Solubility in water, Insoluble
Solubility (soluble in), Chloroform, Benzene
Solubility (slightly sol. in), Acetone
Chemical Name or Material, Zinc Diethyldithiocarbamate
Melting Point, 181°C
Molecular Formula, C10H20N2S4Zn
Quantity, 500 g
Synonym, zinc diethyldithiocarbamate, ethyl ziram, zinc bis diethyldithiocarbamate, diethyldithiocarbamic acid zinc salt, zinc n,n-diethylcarbamodithioate, ethyl zimate, unii-icw4708z8g, ditiocarb zinc, zdc, zdec
SMILES, CCN(CC)C(=S)[S-].CCN(CC)C(=S)[S-].[Zn+2]
Molecular Weight (g/mol), 361.904
Formula Weight, 361.90
Physical Form, Crystalline Powder
CAS, 14324-55-1
Color, White-Yellow
MDL Number, MFCD00064798
UN Number, 3077
InChI Key, RKQOSDAEEGPRER-UHFFFAOYSA-L
IUPAC Name, zinc;N,N-diethylcarbamodithioate
PubChem CID, 26633
Percent Purity, ≥99.0% (T)



SAFETY INFORMATION ABOUT ZINC DIETHYLDITHIOCARBAMATE:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


ZINC DIETHYLDITHIOCARBAMATE (ZDEC)

Zinc diethyldithiocarbamate (ZDEC) is a chemical compound that falls into the category of dithiocarbamates. Its chemical formula is C10H20N2S4Zn.
Zinc diethyldithiocarbamate (ZDEC) is commonly used as an accelerator in the rubber industry, particularly in the production of latex goods and rubber products.
Accelerators are substances that hasten the vulcanization of rubber, which is the process of converting natural or synthetic rubber into a more durable and elastic material.

CAS Number: 14324-55-1
EC Number: 238-270-9



APPLICATIONS


Zinc diethyldithiocarbamate (ZDEC) is widely used as an accelerator in the rubber industry for the vulcanization of natural and synthetic rubbers.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role in the production of tires, providing enhanced strength and durability.

Zinc diethyldithiocarbamate (ZDEC) is commonly employed in the manufacturing of conveyor belts, ensuring they maintain resilience under various conditions.
Latex goods, including gloves and medical products, benefit from ZDEC's contribution to rubber vulcanization.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the production of automotive rubber parts, such as seals and gaskets.

Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber hoses, ensuring they withstand pressure and environmental factors.
Zinc diethyldithiocarbamate (ZDEC) is an essential component in the production of shoe soles, improving the wear resistance of rubber footwear.
Zinc diethyldithiocarbamate (ZDEC) is used in the fabrication of industrial rubber sheets with enhanced mechanical properties.

Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized fabrics, providing them with increased strength and flexibility.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of anti-vibration rubber products, such as mounts and dampers.
Sporting goods like tennis balls and athletic shoe soles benefit from ZDEC in their manufacturing processes.

Rubber linings for chemical and industrial equipment utilize ZDEC to enhance resistance to abrasion and chemicals.
Zinc diethyldithiocarbamate (ZDEC) is integral in the production of cable insulation and other electrical rubber components.
Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized coatings for corrosion protection in various applications.

Zinc diethyldithiocarbamate (ZDEC) finds use in the production of agricultural rubber products, including hoses and belts for machinery.
Zinc diethyldithiocarbamate (ZDEC) is used in the manufacturing of seals and gaskets for appliances, ensuring longevity and reliability.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized roofing materials for weatherproofing and durability.

Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubber compounds for footwear, providing comfort and durability.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the production of rubberized rollers and belts used in industrial machinery.

Zinc diethyldithiocarbamate (ZDEC) is an important ingredient in the formulation of rubber adhesives and sealants.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the creation of marine rubber products, such as boat fenders and seals.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of molded rubber components used in automotive and industrial applications.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the formulation of rubber compounds for automotive belts, ensuring efficient power transmission.

Zinc diethyldithiocarbamate (ZDEC) is employed in the production of rubberized flooring materials for commercial and industrial spaces.
Zinc diethyldithiocarbamate (ZDEC)'s applications extend to various industries, reflecting its versatility and significance in rubber processing.

Zinc diethyldithiocarbamate (ZDEC) is commonly used in the formulation of rubber seals and gaskets for aerospace applications, ensuring reliability and performance under extreme conditions.
Zinc diethyldithiocarbamate (ZDEC) is employed in the production of automotive rubber bushings, contributing to the suspension system's durability and resilience.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the creation of rubberized components for household appliances, such as washing machine seals and hoses.

Zinc diethyldithiocarbamate (ZDEC) is utilized in the manufacturing of inflatable structures, such as rubberized tents and bladders.
Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for anti-fatigue mats, enhancing their longevity and comfort.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized conveyor belts used in mining and material handling industries.
Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubberized footwear for industrial and safety applications, providing protection and comfort.

Zinc diethyldithiocarbamate (ZDEC) is integral in the production of rubberized wheels and casters for material handling equipment.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized rollers for printing and industrial processing machinery.
Zinc diethyldithiocarbamate (ZDEC) finds use in the manufacturing of rubberized inflatable boats, providing durability in marine environments.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized automotive components, including engine mounts and suspension parts.

Zinc diethyldithiocarbamate (ZDEC) is utilized in the formulation of rubber compounds for railway applications, such as track pads and seals.
Zinc diethyldithiocarbamate (ZDEC) is employed in the production of rubberized gloves used in chemical and industrial settings.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the formulation of rubberized diaphragms for pumps and valves in various industries.

Zinc diethyldithiocarbamate (ZDEC) is used in the creation of rubberized packing materials for sealing joints and connections.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized wheels for carts and trolleys in industrial and commercial settings.

Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for oil and gas industry components, such as seals and gaskets.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized components for medical devices, ensuring biocompatibility and durability.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the manufacturing of rubberized expansion joints for bridges and infrastructure projects.

Zinc diethyldithiocarbamate (ZDEC) plays a role in the production of rubberized roller skate wheels, providing resilience and grip.
Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubberized agricultural belts for machinery such as combines and tractors.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized inflatable seals used in aerospace and industrial applications.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized components for water treatment and wastewater systems.

Zinc diethyldithiocarbamate (ZDEC) finds use in the formulation of rubberized components for the production of footwear in the fashion industry.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the manufacturing of rubberized anti-vibration mounts for machinery and equipment.

Zinc diethyldithiocarbamate (ZDEC) is commonly employed in the formulation of rubberized automotive weatherstripping, contributing to the sealing of vehicle doors and windows.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role in the production of rubberized rollers used in the printing and paper industry for material transport.
Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for the production of inflatable airbags in automotive safety systems.

Zinc diethyldithiocarbamate (ZDEC) is used in the creation of rubberized conveyor belts for food processing and packaging applications.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized components for escalator and elevator systems, ensuring smooth and reliable operation.
Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized pipe seals, providing resistance to environmental factors and maintaining tight seals.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the manufacturing of rubberized diaphragms for control valves and actuators in industrial processes.

Zinc diethyldithiocarbamate (ZDEC) is utilized in the production of rubberized vibration isolation mounts for electronic equipment and sensitive machinery.
Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubber compounds for the production of seals and gaskets in plumbing applications.
Zinc diethyldithiocarbamate (ZDEC) finds application in the creation of rubberized components for amusement park rides, ensuring safety and durability.

Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized conveyor belts used in the mining and aggregates industry.
Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized components for marine fender systems, providing impact resistance at docks and ports.
Zinc diethyldithiocarbamate (ZDEC) is used in the manufacturing of rubberized expansion joints for bridges and highway construction projects.

Zinc diethyldithiocarbamate (ZDEC) plays a role in the formulation of rubber compounds for the production of durable and weather-resistant roofing materials.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the creation of rubberized components for fitness equipment, such as treadmill belts and resistance bands.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized components for air handling systems, including HVAC duct connectors.

Zinc diethyldithiocarbamate (ZDEC) is employed in the formulation of rubberized components for water and wastewater treatment plants, providing chemical resistance.
Zinc diethyldithiocarbamate (ZDEC) finds application in the creation of rubberized components for military and defense applications, such as protective gear and equipment.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role in the production of rubberized components for oil rigs and offshore platforms, withstanding harsh environmental conditions.

Zinc diethyldithiocarbamate (ZDEC) is used in the formulation of rubberized components for medical devices, ensuring compliance with healthcare standards.
Zinc diethyldithiocarbamate (ZDEC) contributes to the production of rubberized components for the aerospace industry, including seals and gaskets for aircraft.
Zinc diethyldithiocarbamate (ZDEC) is employed in the creation of rubberized components for solar panel installations, providing durability and weather resistance.

Zinc diethyldithiocarbamate (ZDEC) finds application in the formulation of rubber compounds for the production of durable and slip-resistant sports surfaces.
Zinc diethyldithiocarbamate (ZDEC) plays a role in the manufacturing of rubberized components for the construction industry, including seals for doors and windows.
Zinc diethyldithiocarbamate (ZDEC) is utilized in the creation of rubberized components for renewable energy applications, such as wind turbine seals and gaskets.



DESCRIPTION


Zinc diethyldithiocarbamate (ZDEC) is a chemical compound that falls into the category of dithiocarbamates. Its chemical formula is C10H20N2S4Zn.
Zinc diethyldithiocarbamate (ZDEC) is commonly used as an accelerator in the rubber industry, particularly in the production of latex goods and rubber products.
Accelerators are substances that hasten the vulcanization of rubber, which is the process of converting natural or synthetic rubber into a more durable and elastic material.

Zinc diethyldithiocarbamate (ZDEC), like other dithiocarbamates, contains a dithiocarbamate group (-S2CNRR'), where R and R' are organic groups.
The presence of zinc in ZDEC provides additional stability and effectiveness as a vulcanization accelerator.

Zinc diethyldithiocarbamate, commonly known as ZDEC, is a chemical compound used in the rubber industry.
Zinc diethyldithiocarbamate (ZDEC) is characterized by its molecular formula C10H20N2S4Zn.
Zinc diethyldithiocarbamate (ZDEC) plays a crucial role as a vulcanization accelerator in the production of rubber products.

With a CAS Registry Number of 14324-55-1, ZDEC is identifiable in chemical databases.
Zinc diethyldithiocarbamate (ZDEC) contains a dithiocarbamate group, which contributes to its rubber vulcanization properties.
The presence of zinc in Zinc diethyldithiocarbamate (ZDEC) enhances its stability and accelerates the vulcanization process.

Rubber goods such as latex products often incorporate ZDEC to improve their durability and elasticity.
As an accelerator, Zinc diethyldithiocarbamate (ZDEC) facilitates the cross-linking of polymer chains in rubber, enhancing its strength.
Zinc diethyldithiocarbamate (ZDEC) is integral in ensuring that rubber products achieve the desired physical properties.
Zinc diethyldithiocarbamate (ZDEC) is used in the production of various rubber items, including tires, hoses, and conveyor belts.

Its EC number, 238-270-9, is associated with its registration in the European Community.
Zinc diethyldithiocarbamate (ZDEC) has a white to pale yellow appearance in its physical state.
Zinc diethyldithiocarbamate (ZDEC) is soluble in common organic solvents, contributing to its ease of use in rubber processing.
Safety data sheets should be consulted and safety precautions followed when handling ZDEC.

Zinc diethyldithiocarbamate (ZDEC) undergoes chemical reactions that promote the curing and hardening of rubber.
Zinc diethyldithiocarbamate (ZDEC)'s application is particularly prevalent in the synthesis of vulcanized rubber for industrial purposes.
Manufacturers carefully control the concentration of ZDEC to achieve optimal vulcanization results.
The molecular structure of ZDEC reflects its ability to act as an efficient accelerator in rubber chemistry.

Rubber compounds with ZDEC exhibit improved resistance to heat, wear, and aging.
Zinc diethyldithiocarbamate (ZDEC) is a key component in formulating rubber compounds with specific performance characteristics.

Zinc diethyldithiocarbamate (ZDEC)'s effectiveness in promoting vulcanization makes it a valuable tool in rubber engineering.
Zinc diethyldithiocarbamate (ZDEC) is part of a family of chemicals known for their contributions to rubber curing processes.
Rubber chemists and engineers rely on ZDEC to achieve precise control over the vulcanization kinetics.

Zinc diethyldithiocarbamate (ZDEC)'s role in rubber processing aligns with the industry's quest for enhanced product performance.
The utilization of Zinc diethyldithiocarbamate (ZDEC) as a vulcanization accelerator underscores its importance in modern rubber technology.



PROPERTIES


Chemical Formula: C10H20N2S4Zn
CAS Registry Number: 14324-55-1
EC Number: 238-270-9
Molecular Weight: Approximately 361.94 g/mol
Physical State: Solid
Color: White to pale yellow
Solubility: Soluble in common organic solvents
Melting Point: Varies, typically in the range of 136-142°C (277-288°F)
Density: Varies, depending on the form and concentration
Odor: May have a characteristic odor
Stability: Stable under normal conditions
Compatibility: Compatible with various rubber polymers
Role: Rubber vulcanization accelerator
Vulcanization Enhancement: Promotes cross-linking of polymer chains in rubber
Accelerator Type: Dithiocarbamate
Presence of Zinc: Enhances stability and accelerates vulcanization
Industrial Applications: Widely used in the rubber industry
Applications: Tire manufacturing, conveyor belts, latex goods, automotive rubber parts, hoses, shoe soles, sporting goods, industrial rubber sheets, seals, gaskets, and various rubber products.
Biodegradability: Information on biodegradability may vary; proper disposal methods recommended.



FIRST AID


Inhalation:

Move the affected person to fresh air.
If the person is not breathing, administer artificial respiration.
Seek medical attention promptly.


Skin Contact:

Remove contaminated clothing.
Wash the affected area with plenty of soap and water.
Seek medical attention if irritation persists or if there are signs of chemical burns.


Eye Contact:

Rinse eyes with plenty of water for at least 15 minutes, lifting the eyelids occasionally.
Seek medical attention if irritation persists or if there is any visual impairment.


Ingestion:

Do not induce vomiting unless directed by medical personnel.
Rinse the mouth with water if the person is conscious.
Seek immediate medical attention.



HANDLING AND STORAGE


Handling Conditions:

Personal Protective Equipment (PPE):
When handling ZDEC, wear appropriate personal protective equipment, including gloves, safety glasses, and a lab coat or protective clothing, to minimize skin contact and protect the eyes.

Ventilation:
Use the chemical in a well-ventilated area to prevent the buildup of vapors.
If ventilation is insufficient, consider using respiratory protection.

Avoid Contact:
Avoid direct skin contact with ZDEC.
In case of skin contact, wash affected areas thoroughly with soap and water.
If irritation persists, seek medical attention.

Avoid Inhalation:
Inhalation of dust or vapors should be avoided.
If respiratory protection is necessary, use appropriate equipment based on workplace exposure levels.

Handling Procedures:
Follow good laboratory or industrial hygiene practices.
Wash hands thoroughly after handling ZDEC and before eating, drinking, or smoking.

Spill Response:
In case of spills, contain the material and clean it up promptly. Use appropriate absorbent materials, and follow established spill response procedures. Dispose of waste in accordance with local regulations.

Storage Compatibility:
Store ZDEC away from incompatible materials, such as strong acids and bases.
Ensure that storage containers are made of materials resistant to corrosion and deterioration.

Temperature Control:
Store ZDEC in a cool, dry place away from direct sunlight and heat sources.
Maintain appropriate temperature conditions to prevent degradation.


Storage Conditions:

Container Selection:
Use containers made of materials compatible with ZDEC.
Consider using tightly sealed containers to prevent moisture ingress.

Labeling:
Clearly label containers with the chemical name, hazard information, and appropriate safety symbols.
This aids in proper identification and safe handling.

Segregation:
Store ZDEC away from incompatible substances to prevent cross-contamination.
Follow segregation guidelines based on chemical compatibility.

Fire Prevention:
ZDEC is not typically considered highly flammable, but it's essential to store it away from open flames, sparks, and heat sources.

Security:
Limit access to storage areas to authorized personnel only.
Store ZDEC in areas designated for chemical storage and ensure compliance with relevant security measures.

Shelf Life:
Adhere to the recommended shelf life of ZDEC as specified by the supplier.
Rotate stock as needed to use older material first.

Monitoring:
Periodically inspect storage areas for signs of damage, leaks, or deterioration of containers.
Address any issues promptly to maintain a safe storage environment.

Emergency Equipment:
Keep emergency response equipment, such as spill kits and fire extinguishers, readily available in the vicinity of the storage area.



SYNONYMS


ZDEC
EZ
Zink-diethyl-dithiocarbamat (German)
Diethyldithiocarbamic Acid Zinc Salt
Ethyl Zimate
Perkacit ZDEC
Rhenocure ZDEC
Rubber Accelerator ZDEC
Zinc Diethyldithiocarbamate
Zinc Diethylthiocarbamate
Zinc Salt of Diethyldithiocarbamic Acid
Zinc Bis(diethylcarbamodithioate)
Zinc Diethylxanthate
Diethylzinc Dithiocarbamate
Zinc(II) N,N-Diethyldithiocarbamate
ZDEC Accelerator
Zinc Salt of Diethyldithiocarbamate
N,N-Diethyldithiocarbamic Acid Zinc Salt
Bis(diethyldithiocarbamato)zinc
Zinc(II) Diethyldithiocarbamate
Zinc(II) Ethylxanthate
Perkacit EZ
Accicure ZDEC
Ethyl Ziram
Zinc Ethylxanthate
Zinc Diethyl Dithiocarbamate
Ethyl N,N-Diethyldithiocarbamate Zinc Salt
Rhenogran ZDEC-80
Rubber Accelerator PX
Zinc(II) Salt of Diethyldithiocarbamic Acid
Zink-diethyl-ditiokarbamat (Swedish)
Dithiocarbamic Acid, Zinc Salt, Diethyl Ester
Zineb Accelerator
Zinc(II) Diethyldithiocarbamate
Nocceler ZDEC
Vulkacit L 80
ZINC GLUCOHEPTONATE
ZINC GLYCINATE N° CAS : 14281-83-5 Nom INCI : ZINC GLYCINATE Nom chimique : Glycine, Zinc Salt N° EINECS/ELINCS : 238-173-1 Classification : Règlementé Restriction en Europe : III/24 Ses fonctions (INCI) Régulateur de pH : Stabilise le pH des cosmétiques
ZINC GLUCONATE
ZINC GLUCONATE = ZINCUM GLUCONICUM = GLUCONIC ACID ZINC SALT


CAS Number: 4468-02-4
EC Number: 224-736-9
Chemical formula: C12H22O14Zn


Zinc Gluconate is obtained by connecting 2 gluconic acids to a Zn +2 zinc cation structurally.
Zinc Gluconate has great importance in biological structure.
Zinc Gluconate is not known exactly what mechanism of action it has.
But Zinc Gluconate is known as an organic zinc supplement agent.


Zinc gluconate is an essential trace element for the proper functioning of many chemical reactions that occur in the human body, as it contributes to the regulation of about 300 enzymes as well as protein synthesis.
Zinc gluconate is the zinc salt of gluconic acid.
Zinc Gluconate is an ionic compound consisting of two anions of gluconate for each zinc(II) cation.


Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement providing 14.35% elemental zinc by weight.
Zinc is an essential mineral responsible for a number of different functions in the human body.
Zinc Gluconate supports healthy immune system functions and cell regeneration.
Zinc Gluconate helps to stimulate the activity of over one hundred different enzymes and it is vital for protein synthesis.


Essential trace element for the body, as Zinc Gluconate is a key ingredient for more than 150 enzymes.
Zinc Gluconate plays a key role in the process of protein synthesis (DNA & RNA synthesis) and due to this property it shows a wide range of indications.
Zinc Gluconate is a nutritional supplement containing the zinc salt form of gluconic acid for the purpose of providing zinc.


As an essential trace element, zinc is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system.
Zinc Gluconate is available in the form of white powder or granules.
The pH value of Zinc Gluconate is in the range of 5.5-7.5 in its solution at 0.01 g/ml.
Zinc Gluconate dissolves well in water as solubility.


Zinc Gluconate is insoluble in methylene chloride and pure ethanol .
Zinc Gluconate's melting point is in the range of 172-175 °C.
Zinc Gluconate's Boiling Point is 673.6 °C.


Zinc Gluconate's density is 2.907 g/cm3 .
Zinc Gluconate store away from moisture and at room temperature.
There are different forms of zinc, with zinc gluconate being the most common.
Studies show that in the elderly population, zinc supplements potentially improve immunity.


Zinc is a mineral in nature.
In the body, this is called an "essential trace element" because a very small amount of zinc already has an essential role for human health.
Since the human body cannot store excess zinc, this element needs to be consumed regularly as part of the daily diet.
Common natural food sources of zinc include red meat, poultry, and fish.


Zinc deficiency can result in short stature in young children, reduced ability to taste and smell, and limited activity in the testicles and ovaries.
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+).
Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA.


Zinc Gluconate is a L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo.
Zinc gluconate (also called zincum gluconicum) is the zinc salt of gluconic acid.
Zinc Gluconate is an ionic compound consisting of two moles of gluconate for each mole of zinc.
Zinc gluconate is a popular form for the delivery of zinc as a dietary supplement.


Gluconic acid is found naturally, and is industrially manufactured by the fermentation of glucose, but also by other fungi, e.g. Penicillium, or by bacteria, e.g. Acetobacter, Pseudomonas and Gluconobacter. In its pure form, it is a white to off-White powder.
Zinc Gluconate can also be manufactured by electrolytic oxidation, although this is a more expensive process.
The advantages are a lower microbiological profile, and a more complete reaction, yielding a product with a longer shelf life.


Zinc Gluconate is a supplement that can provide zinc to the body.
Zinc Gluconate is zinc salt of gluconic acid, a mild acid produced from the sugar glucose.
Despite the in-part sugar origins, this is a synthetic ingredient that functions as a preservative.
Interestingly, the human body produces gluconates on its own to assist in obtaining nutrients from minerals.


Zinc is an essential mineral responsible for a number of different functions in the human body.
Zinc Gluconate supports healthy immune system functions and cell regeneration.
Zinc Gluconate helps to stimulate the activity of over one hundred different enzymes and it is vital for protein synthesis.
Zinc Gluconate is a nutritional supplement containing the zinc salt form of gluconic acid for the purpose of providing zinc.


Zinc gluconate is produced by complete neutralisation of gluconic acid with a high purity zinc source and subsequent spray-drying.
Zinc gluconate is supplied as a white to almost white, granular or crystalline powder.
Zinc Gluconate shows a good solubility and fast dissolution speed in water and is practically insoluble in alcohol.
Zinc deficiency affects about 1 in 3 people worldwide.


Signs of Zinc deficiency include wounds that take time to heal, trouble concentrating, stomach problems, decreased sense of smell and taste, hair loss, loss of appetite and unexplained weight loss.
Fertility problems can be exacerbated by a lack of sufficient Zinc.
Recurring health problems related to a low immune system could also be an indication of Zinc deficiency.



USES and APPLICATIONS of ZINC GLUCONATE:
Zinc gluconate is considered safe as used in cosmetics.
Zinc Gluconate’s also used in over-the-counter oral lozenges designed to combat the common cold.
Zinc Gluconate is used as a dietary supplement, adults take one tablet daily preferably with a meal or as recommended by a physician.
As a dietary supplement, adults take one (1) tablet daily with a meal or as directed by a health care professional.


Zinc Gluconate is ideal in cases of oligospermia, acne, macular degeneration, ulcers, burns and common cold.
Zinc Gluconate is treated as a dietary supplement to provide the form of gluconic acid.
In medicine, zinc is taken orally to treat and prevent zinc deficiency and its consequences, including growth retardation, acute diarrhea in children, prolonged wound healing, and Wilson's disease.


Besides, elemental zinc, in the form of zinc gluconate salt is also used to strengthen the immune system, improve growth and health in zinc-deficient infants and children, to treat common colds common and recurrent ear infections, influenza, upper respiratory tract infections, prevention and treatment of lower respiratory tract infections as well as used for malaria and other diseases caused by parasites.
Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV).


Zinc Gluconate is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
As a pharmaceutical chemical, gluconic acid plays a role in activating many important enzymes with antioxidant effects.
In this way, Zinc Gluconate has the effect of preventing the damage of oxygen free radicals.


Since Zinc Gluconate is a very good source of zinc, in addition to the effect of inducing T lymphocyte activation, gluconic acid supplemented drugs are produced to protect the metabolic structure by activating B lymphocytes and to ensure the permeability of the cell membrane.
Zinc gluconate (Zinc Gluconate) formulated products are applied in the manufacture of oral care products to reduce bad odors, prevent tartar formation and protect dental plaques.


Zinc Gluconate is used as a food additive in some diet products.
Zinc Gluconate is used as an alternative to zinc sulfate because it has less side effects and better absorption than zinc sulfate.
Biologically, there is approximately 1.6 times more utilization than Zinc sulfate .
Zinc Gluconate is used as a drug active ingredient for the diabetes treatment of people who are not dependent on insulin resistance.


Zinc Gluconate increases the body's insulin sensitivity.
A pressure ulcer results in skin and tissue damage due to reduced blood circulation in a particular area of ​​the body.
Zinc Gluconate is used in the manufacture of drugs or food supplements used in the treatment of pressure ulcers.
The reason for using here is; Zinc has an important role in many enzymatic reactions.


Zinc Gluconate helps to create a mental clarity effect by using it together with Ascorbic Acid , Magnesium Sulphate and Caffeine in the production of Multivitamin Supplements .
Zinc Gluconate is used in the production of drugs containing D-Gluconate for the good functioning of protein synthesis in the body, healing of wounds and stabilization of blood values.


Zinc is a mineral that is used as a dietary supplement in people who do not get enough zinc from food.
Zinc gluconate lozenges are used to help make cold symptoms less severe or shorter in duration.
This includes sore throat, cough, sneezing, stuffy nose, and a hoarse voice.
Zinc gluconate is not effective in treating flu or allergy symptoms.


Zinc gluconate may also be used for purposes not listed in this medication guide.
Zinc is a mineral that is used as a dietary supplement in people who do not get enough zinc from food.
Zinc Gluconate is used as an essential trace element, zinc is of key importance in many biological processes, acts as an antioxidant and strengthens the immune system.


Although the mechanism of action is not completely known, zinc supplementation may be used to increase immunity against viruses or may interfere with the replication of certain viruses, such as the human papillomavirus (HPV).
Zinc in the form of Zinc Gluconate contains 10mg of elemental Zinc which is easily assimilated in the body.
Zinc is involved in a great number of biological functions.


Zinc Gluconate aids normal cell division, which makes it especially important for growth and development during pregnancy and childhood.
Zinc Gluconate is involved in bone formation and mineralisation, helping to maintain strong bones and teeth.
Zinc also plays an important role in collagen and protein synthesis, vision, sexual function, fertility, antioxidant activity, immunity and much more.


Zinc gluconate is mainly used as a mineral source in functional food, beverages and food supplement preparations.
Zinc Gluconate's excellent solubility properties make it perfect for liquid and powdered applications.
As an organic mineral source, Zinc Gluconate is preferred in many applications over inorganic sources because of its superior bioavailability, physiological compatibility and nearly neutral taste compared to other zinc salts.


Due to its skin-conditioning properties, Zinc Gluconate is also used in skin care products.
Zinc Gluconate can be used as a dietary ingredient and as a nutrient.
Zinc is an important antioxidant nutrient.
Zinc Gluconate is necessary for protein synthesis, wound healing, for blood stability, normal tissue function, and aids in the digestion and metabolism of phosphorus.


Zinc Gluconate also governs the contractility of muscles and maintains the body’s alkaline balance.
Zinc Gluconate helps strengthen the immune system, skin health, healthy sperm production, prostate health and has a high antioxidant effect.
Zinc Gluconate is ideal for protection against colds and viruses.
Zinc Gluconate is used supply of zinc for human and veterinary medicine (oral or injection)


Zinc Gluconate is used in anti-acne preparations and to reduce the duration of common cold symptoms.
Zinc Gluconate is used as a mineral source in dietary supplements, in dairy product, in beverages and in baby food.
Zinc Gluconate is used sequestrant, acidifier, leavening agent, curing agent in nonalcoholic beverages, processed.
Zinc Gluconate is used fruit and fruit juices, baked goods, dairy products and cured meats.


Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children.
Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks.


Zinc is known to play a critical role in cell growth, wound healing, immunity, protein synthesis, DNA synthesis, and it is required for taste and smell to work correctly.
Thus, it is crucial to almost every aspect of your health.
Therefore, people at risk of zinc deficiency are advised to include foods high in zinc in their daily diets.


In certain situations, a doctor might also recommend a zinc supplement.
Zinc gluconate is used as one of the most common OTC forms, zinc gluconate is often used in cold remedies like lozenges and nasal sprays.
Zinc Gluconate’s score is higher if used in products that are inhalable (e.g., sprays, powders) because of respiratory concerns.


Some patients are also prescribed zinc supplements for an eye disease called macular degeneration, night blindness and cataracts.
On the other hand, the role of zinc has also been demonstrated in asthma, diabetes and diabetes-related nerve damage; High Blood Pressure; HIV/AIDS or pregnancy complications, HIV-associated diarrhea and AIDS-related malabsorption syndromes, AIDS-related infections, and hyperbilirubinemia.


In addition, zinc gluconate is also involved in the treatment of anorexia nervosa, obsessive-compulsive disorder, depression, memory loss, dry mouth, attention deficit hyperactivity disorder, hepatic encephalopathy, liver related diseases to alcohol, ulcerative colitis, inflammatory bowel disease, mouth ulcers, stomach ulcers, leg ulcers, and pressure ulcers.
Main uses Zinc gluconate is an effective treatment for zinc deficiency.


Zinc deficiency can occur in people with severe diarrhea, a condition that makes it difficult for the intestines to absorb food, cirrhosis of the liver, and alcoholism.
This condition can also occur after major surgery and during prolonged use of tube feeding in the hospital.
Indications to use zinc orally or give zinc intravenously will help quickly restore zinc levels in people with zinc deficiency.
However, regular zinc supplementation is not recommended.


-Additional Uses Diarrhea :
Taking zinc gluconate tablets by mouth has been shown to reduce the duration and severity of diarrhea in undernourished or zinc-deficient children.
Severe zinc deficiency in children is a common condition in developing countries.
Simultaneously, clinicians need to provide zinc to undernourished women during pregnancy and continue until one month postpartum to reduce the incidence of neonatal diarrhea within the first year of life.


-Wilson's disease:
Taking zinc daily improves symptoms of a genetic disorder known as Wilson's disease.
People with Wilson's disease often have too much copper in their bodies.
At this time, the element zinc will prevent copper from being absorbed and increase the amount of copper released by the body.


-Skin acne:
Studies show that people with acne have lower blood and skin zinc levels than the general population.
Thus, taking zinc supplements will help treat acne.
However, it is still unclear how beneficial zinc is compared to acne medications such as tetracycline or minocycline.
Therefore, topical application of zinc in ointments does not appear to help treat acne unless used in combination with the antibiotic erythromycin.


-Age-related vision loss:
It is macular degeneration in the elderly.
Observational studies show that people who consume more zinc as part of their diet have a reduced risk of age-related vision loss.
Therefore, supplementation with zinc and antioxidant vitamins may mitigate and prevent age-related vision loss in high-risk individuals.


-Anorexia:
Taking zinc supplements by mouth may help with weight gain and improve symptoms of depression in adolescents and adults with anorexia.
Zinc Gluconate is an over-the-counter dietary supplement that contains a zinc, a mineral that is used throughout the body.
Zinc Gluconate is used to treat zinc-deficiency and as a cold remedy.


-Zinc gluconate and the common cold:
Zinc gluconate has been used in lozenges for treating the common cold.
However, controlled trials with lozenges which include zinc acetate have found it has the greatest effect on the duration of colds.


-Veterinary uses of Zinc Gluconate:
A zinc gluconate-based product, also containing arginine, is used as a veterinary chemical castration drug.
Zinc gluconate, a skin-absorbable zinc derivative, is a powerful sebum stabilizer that visibly rebalances and mattifies the skin.
Zinc Gluconate is an indispensable ingredient for combination and oily skin.


-Zinc Gluconate can be used for:
*Zinc deficiency symptoms
*Wound healing and skin ulcers, acne treatment and hair loss
*To increase sperm count & motility
*To boost the immune system; zinc plays a major role as an immune enhancer against all viruses and other micro-organisms
*To cut short the common cold and diarrhea
*To support the senses of taste and smell, boost brain activity and enhance memory
*To support normal growth and development
*Zinc Gluconate 76 mg supplies the body with 11 mg of elemental Zinc which is considered the highest concentration Zinc found in one tablet.


-Accelerating wound healing:
Zinc supplements and products are often used to treat skin ulcers, burns, and injuries, as zinc maintains the integrity of the skin.
Zinc is known to be essential in every phase of the wound healing process, from injury right through to repair/remodeling.


-Decreasing inflammation:
Zinc has several antioxidant and anti-inflammatory effects, including reducing oxidative stress.
Oxidative stress is responsible for the development of chronic diseases such as cancer, cardiovascular disease, hypertension, diabetes mellitus, neurodegenerative diseases, rheumatoid arthritis, and more.
Therefore, researchers suggest that zinc supplementation may potentially prove to be a useful intervention to assist.
May potentially delay the progression of age-related macular degeneration and vision loss
Studies have shown that zinc could delay the progression of age-related macular degeneration and vision loss.
Another study of the elderly population in the Netherlands also showed that a high dietary intake of beta carotene, vitamins C and E, and zinc was associated with a substantially reduced risk of age-related macular degeneration.


-May help treat acne:
Some clinical studies suggest that both topical and oral zinc treatments can effectively treat acne.
It is thought that zinc:
*Reduces inflammation:
Inhibits the growth of specific bacteria, which cause acne.
Suppress oily gland activity.
May reduce the severity and duration of cold symptoms
Several studies have shown that zinc potentially reduces cold symptoms.
For example, one study found that zinc lozenges were associated with reduced duration and severity of cold symptoms.
Another review also concluded that zinc lozenges or syrup are beneficial in reducing the duration and severity of cold symptoms when started within 24 hours.

If you are fighting acne and have looked into oral supplements, chances are that zinc gluconate sounds familiar to you.
It is a zinc salt that has research proving it to be effective against inflammatory acne, though not quite as effective as the antibiotic minocycline (31.2% vs. 63.4% success rate).
However, zinc supplements are easily available, have little-to-no side effects, so supplementing them with a 30mg per day dose can still be a good idea.

As for smearing zinc gluconate all over your face, it is also not a bad idea.
Zinc has multiple magic abilities: it is antibacterial (including evil, acne-causing P. acnes) and sebum-regulating (5α-reductase inhibitor), great for acne-prone skin types.
It also stimulates antioxidant enzyme systems (mainly superoxide dismutase) and has nice wound healing abilities acting mainly in the first, proliferation phase.
So great for skin types in need of healing and soothing.



KEY BENEFITS OF ZINC GLUCONATE:
*Zinc Gluconate helps to maintain valuable nutritional support for the immune system, prostate, and eyes
*This essential mineral, Zinc Gluconate, is a crucial component of the body’s primary antioxidant enzymes
*Zinc Gluconate helps support healthy immune system functions
*Zinc Gluconate supports healthy neurological functions
*Zinc Gluconate helps to regulate the blood glucose level of the body



WHAT ARE SOME POTENTIAL BENEFITS OF ZINC GLUCONATE?
Zinc is found in every cell in the human body and is required for the activity of about 100 enzymes.
The potential benefits of zinc gluconate include:
*Supporting your immune system
*Zinc plays an essential role in the immune system, and severe zinc deficiency suppresses your immune function.
*Zinc is needed to develop and activate T-lymphocytes (important white blood cells of the immune system).



THE IMPORTANCE OF ZINC GLUCONATE FOR PREVENTING THE COMMON COLD:
Two of the most important components for the protection of health by defending the immune system in humans are Vitamin C and Zinc.
Cold diseases caused by insufficient intake of these compounds and elements cause great losses and economic problems for societies.
Both substances have been used separately for a very long time and have been studied in the field of pharmacology and dietary supplements.
The products prepared by combining Ascorbic Acid (Vitamin C) and Zinc Gluconate showed its effect within 5 days of the disease when applied to patients with colds.
Zinc Gluconate has been found that this method is more effective than other applications.
In addition, Zinc Gluconate has been understood that the symptoms that are indicative of the disease are resolved in a shorter time.
As a result, Zinc Gluconate has been determined that a good zinc supplement (Zinc Gluconate, Zinc Sulphate ) and Ascorbic Acid (Vitamin C) modification will be important in preventing the disease of this contagious viral disease.



WHAT ABOUT THE GLUCONATE PART?
Zinc Gluconate is there to promote the absorption and bioavailability of zinc and also plays a role in cellular regeneration (involved in the synthesis of ribose sugars, structural components of DNA and RNA).



PHYSICAL and CHEMICAL PROPERTIES of ZINC GLUCONATE:
Chemical formula: C12H22O14Zn
Molar mass: 455.685 g/mol
Melting point: 172 to 175 °C (342 to 347 °F; 445 to 448 K)
Molecular Weight: 455.7
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 14
Rotatable Bond Count: 8
Exact Mass: 454.030097
Monoisotopic Mass: 454.030097
Topological Polar Surface Area: 283 Ų
Heavy Atom Count: 27
Formal Charge: 0
Complexity: 165
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 8
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes

Molecular Formula: C12H22O14Zn
Melting Point: 131ºC
Flash Point: 375.2ºC
Appearance: In its pure form, it is a white to off-white powder
Storage Keep tightly closed in a cool place in a tightly closed container.
HS Code: 2918160000
Log P: -7.14290
PSA: 254.9
RTECS: ZH3750000
Stability: Stable.
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 172 - 175 °C - lit.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
Appearance: Powder
Color: White
Molecular weight: 455.7 g/mol
Theoretical zinc content: 14.35%
Soluble in Water: Water solubility (20°C) 100 g/L
Practically insoluble in Ethanol
Insoluble in Acetone, chloroform and toluene



FIRST AID MEASURES of ZINC GLUCONATE:
-Description of first-aid measures:
*General advice:
Consult a physician.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
If breathed in, move person into fresh air.
Consult a physician.
*In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC GLUCONATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Sweep up and shovel.
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ZINC GLUCONATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC GLUCONATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses with side-shields.
*Skin protection:
Handle with gloves.
Wash and dry hands.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC GLUCONATE:
-Precautions for safe handling:
*Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Store under inert gas.
hygroscopic
*Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids



STABILITY and REACTIVITY of ZINC GLUCONATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Gluconic Acid Zinc Salt
Zinc Gluconate Hydrate
Zinc Gluconate (USP)
pentahydroxyhexanoate
4468-02-4
Zinc(II) Gluconate
Zinc source
D-Gluconate
D-Gluconic Acid
Zinc Gluconate Anhydrate
ZINC GLUCONATE
4468-02-4
Zincgluconate
Zincum gluconicum
Gluconic acid zinc complex
Zinc D-gluconate (1:2)
Bis(D-gluconato-O1,O2) zinc
Gluconic Acid Zinc(II) Salt
Zinc gluconate (USP)
U6WSN5SQ1Z
Zinc, bis(D-gluconato-kappaO1,kappaO2)-, (T-4)-
Gluconic acid zinc
Zinc(II) Gluconate
SCHEMBL21280
CHEMBL3833377
CHEBI:29708
DTXSID20894125
AKOS015951235
DB11248
G0277
D02390
F71322
A826659
Q-201160
Q3822815
Zinc(II) (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
zinc (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate
Zinc gluconate hydrate
Zinegluconate
Rubozinc
GLUCONIC ACID ZINC SALT
Gluconic Acid Zinc(II) Salt
Zinc(II) gluconate hydrate


ZINC GLYCINATE
ZINC LACTATE N° CAS : 16039-53-5 Nom INCI : ZINC LACTATE Nom chimique : Zinc dilactate N° EINECS/ELINCS : 240-178-9 Classification : Règlementé Compatible Bio (Référentiel COSMOS) Restriction en Europe : III/24 Ses fonctions (INCI) Déodorant : Réduit ou masque les odeurs corporelles désagréables
ZINC LACTATE
ZINC LAURATE N° CAS : 2452-01-9 Nom INCI : ZINC LAURATE Nom chimique : Zinc dilaurate N° EINECS/ELINCS : 219-518-5 Ses fonctions (INCI) Anti Agglomérant : Permet d'assurer la fluidité des particules solides et de limiter leur agglomération dans des produits cosmétiques en poudre ou en masse dure Opacifiant : Réduit la transparence ou la translucidité des cosmétiques Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ZINC LAURATE
ZINC MYRISTATE N° CAS : 16260-27-8 Nom INCI : ZINC MYRISTATE Nom chimique : Zinc dimyristate N° EINECS/ELINCS : 240-369-7 Ses fonctions (INCI) Anti Agglomérant : Permet d'assurer la fluidité des particules solides et de limiter leur agglomération dans des produits cosmétiques en poudre ou en masse dure Opacifiant : Réduit la transparence ou la translucidité des cosmétiques Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
ZINC MYRISTATE
SYNONYMS Zinc white; Zinc flowers ; C.I. pigment white 4; ZnO; CAS NO. 1314-13-2
ZINC N, N-DI-N-BUTYLDITHIOCARBAMATE/DI-N-BUTYLAMINE COMPLEX (ZDBCX)

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a complex compound recognized for its role as an ultra-accelerator in rubber processing.
The chemical formula of ZDBCX reveals its unique composition, involving zinc, dibutylamine, and dithiocarbamate moieties.
In its liquid state, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) presents itself as a light brown, slightly turbid liquid.
When encountered, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) emits a faint odor reminiscent of dibutylamine, providing a distinctive olfactory cue.

CAS Number: 136-23-2
EC Number: 205-232-8



APPLICATIONS


Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) serves as a crucial ultra-accelerator in rubber processing, finding widespread applications in the rubber industry.
In natural rubber and SBR formulations, ZDBCX acts as a versatile accelerator, contributing to the efficient curing of rubber compounds.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is specifically valued for its ability to be active at room temperature, streamlining rubber processing procedures.
Transparent and translucent articles benefit significantly from ZDBCX, where it enhances the curing process and maintains color stability.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the preparation of dry mixes, cements, and latex products, showcasing its adaptability in different rubber applications.
Its ultra-accelerating properties make ZDBCX a vital component in the manufacturing of tires, conveyor belts, seals, and various rubber products.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) can be used as a booster for thiazoles, offering compatibility with other rubber accelerators to achieve optimal performance.
In cements, ZDBCX acts as a liquid miscible with rubber solvents, simplifying the preparation process and ensuring even distribution in the final product.

Its addition at the solution stage in cements eliminates the need for incorporation on the mixing mill, streamlining production procedures.
ZDBCX exhibits a short pot-life in finished cements, indicating its rapid curing capabilities and requiring careful handling during application.

The accelerator is used in dry natural rubber processing, where its low-temperature properties and compatibility with milling processes make it valuable.
Extrusion of rubber mixes containing ZDBCX is feasible without scorching, showcasing its suitability for various processing methods.

Hot air curing of rubber mixes with ZDBCX is achieved at relatively low temperatures, contributing to energy-efficient production.
Footwear applications, such as soles, benefit from ZDBCX in translucent SBR compounds, where it enhances curing processes.
ZDBCX can be combined with sulphenamide or thiazole accelerators in translucent SBR compounds for optimal curing results.

The accelerator system with ZDBCX and sulphenamide or thiazole is well-suited for the production of high-quality footwear components.
The use of ZDBCX in rubber formulations contributes to the overall performance, durability, and quality of the final rubber products.

Its applications extend to the preparation of latex products, where it facilitates the curing process and imparts desirable properties to the finished items.
ZDBCX is employed in the manufacturing of rubber goods where transparency or translucency is a desired feature, such as certain seals or gaskets.

The complex's ability to be further activated by Z.I.X. broadens its application scope, providing additional flexibility in rubber processing.
ZDBCX plays a role in minimizing curing times in various rubber applications, enhancing production efficiency.

When incorporated in specific proportions, ZDBCX accelerates the curing of rubber compounds, contributing to shorter processing times.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) contributes to the production of high-quality rubber products with desirable physical and chemical properties.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX)'s compatibility with different rubber types, including natural rubber, SBR, and latex, makes it a versatile choice for various formulations.
Its applications span a range of industries, emphasizing its significance as a key component in rubber processing for diverse end-use products.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is extensively utilized in the production of rubber seals and gaskets due to its efficient curing properties and non-staining characteristics.
Its compatibility with different rubber matrices makes ZDBCX a preferred choice for the manufacturing of a variety of rubber components.
In the automotive industry, ZDBCX finds application in the formulation of rubber parts such as bushings, grommets, and vibration isolators.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX)'s ability to impart transparency to rubber compounds makes it valuable in the production of clear or lightly colored rubber products.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the preparation of rubber belts, where its curing capabilities contribute to the strength and durability of the final product.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a key ingredient in the manufacturing of conveyor belts, providing accelerated curing for improved processing efficiency.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is used in the production of rubber hoses, ensuring quick curing times and enhancing the overall performance of the hoses.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubber sheets, contributing to faster curing and improved properties of the final material.
In the construction industry, ZDBCX is utilized in rubberized asphalt for improved performance, durability, and curing efficiency.

Rubber rollers used in various industrial applications benefit from the accelerated curing provided by ZDBCX in the rubber compound.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the formulation of rubber gloves, where its non-staining properties are crucial for maintaining product aesthetics.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a role in the production of rubberized fabrics, contributing to the material's enhanced strength and curing characteristics.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the manufacturing of rubberized footwear, ensuring rapid curing for efficient production processes.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the formulation of rubberized adhesives, where its properties contribute to quick curing and strong adhesive bonds.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the production of rubberized coatings, providing accelerated curing for enhanced coating performance.
In the electrical industry, ZDBCX is used in the formulation of rubber insulating materials, ensuring efficient curing and product reliability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a crucial component in the production of rubber seals for windows and doors, contributing to the longevity and performance of the seals.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a role in the manufacturing of rubberized sports equipment, ensuring rapid curing and improved material properties.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) contributes to the production of rubberized footwear components, such as insoles and outsoles, with desirable curing characteristics.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the formulation of rubberized linings for tanks and containers, providing enhanced resistance and efficient curing.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the production of rubberized rollers for printing presses, ensuring quick curing and prolonged durability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the formulation of rubberized automotive parts, contributing to the efficiency and reliability of these components.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the production of rubberized medical devices, where quick curing times are critical for efficient manufacturing.

In the aerospace industry, ZDBCX finds applications in the formulation of rubber components for aircraft, ensuring efficient curing and performance.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the manufacturing of rubberized industrial belts, providing accelerated curing for improved processing efficiency and longevity.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a key ingredient in the production of rubberized automotive hoses, ensuring quick and efficient curing for reliable performance.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the formulation of rubberized engine mounts and bushings, contributing to enhanced durability and vibration damping.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the manufacturing of rubberized industrial seals, providing accelerated curing for improved sealing properties.

In the production of rubberized footwear, such as shoe soles, ZDBCX plays a vital role in ensuring fast curing and high-quality end products.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the formulation of rubberized conveyor belts, contributing to rapid curing and increased strength for material transport applications.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the production of rubberized rollers for printing and laminating processes, ensuring quick curing and prolonged durability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds use in the formulation of rubberized marine components, contributing to efficient curing and improved resistance to environmental factors.

In the electronics industry, ZDBCX is employed in the production of rubberized components for electronic devices, ensuring quick curing and reliability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is used in the formulation of rubberized expansion joints, providing accelerated curing for improved flexibility and durability.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a role in the manufacturing of rubberized belting for industrial machinery, ensuring rapid curing for increased operational efficiency.
In the production of rubberized gaskets and seals for pipelines, ZDBCX contributes to quick curing and effective sealing properties.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubberized inflatable products, ensuring fast curing for the production of airtight and durable items.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the production of rubberized seals for hydraulic and pneumatic systems, ensuring efficient curing and reliable performance.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the formulation of rubberized agricultural components, contributing to quick curing and increased resilience in the field.
In the textile industry, ZDBCX is employed in the production of rubberized fabric for various applications, ensuring accelerated curing and improved strength.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) plays a crucial role in the formulation of rubberized roof membranes, contributing to quick curing and enhanced weather resistance.
The complex is utilized in the production of rubberized power transmission belts, ensuring rapid curing for efficient energy transfer in machinery.

In the production of rubberized industrial gloves, ZDBCX contributes to quick curing times, essential for high-volume manufacturing processes.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubberized medical tubing and hoses, ensuring efficient curing for the production of reliable medical devices.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is employed in the manufacturing of rubberized rollers for material handling and processing equipment, ensuring quick curing and extended service life.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is used in the formulation of rubberized tank linings, contributing to rapid curing and increased resistance to chemical substances.
In the production of rubberized vibration isolators and mounts, ZDBCX ensures quick curing and effective damping properties.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds applications in the formulation of rubberized components for sports equipment, contributing to quick curing and enhanced durability.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is utilized in the production of rubberized shock absorbers, ensuring rapid curing for efficient automotive suspension systems.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is applied in the formulation of rubberized coatings for industrial applications, contributing to quick curing and enhanced protective properties.



DESCRIPTION


Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is a complex compound recognized for its role as an ultra-accelerator in rubber processing.
The chemical formula of ZDBCX reveals its unique composition, involving zinc, dibutylamine, and dithiocarbamate moieties.
In its liquid state, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) presents itself as a light brown, slightly turbid liquid.

When encountered, Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) emits a faint odor reminiscent of dibutylamine, providing a distinctive olfactory cue.
Storage stability is a notable characteristic of ZDBCX, exhibiting good resilience if kept in cool and dry conditions within sealed containers.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) boasts non-discoloring and non-staining properties, making it valuable for applications requiring color stability.

With a minimum purity of 97%, ZDBCX assures a high level of chemical integrity in its composition.
Solubility in aliphatic and aromatic hydrocarbons, coupled with potential emulsification in water, highlights the versatility of ZDBCX in various formulations.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) finds utility as an accelerator in natural rubber and SBR, particularly in the preparation of dry mixes, cements, and latex products.

Its ultra-accelerating properties make ZDBCX active at room temperature, facilitating efficient rubber curing processes.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) can be further activated by Z.I.X., enhancing its accelerating capabilities in rubber applications.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) serves as an effective booster for thiazoles, demonstrating compatibility with other rubber accelerators.
Transparent and translucent articles derived from both latex and dry rubber benefit significantly from the use of ZDBCX in their formulation.

Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is composed of intricate molecular structures, contributing to its unique performance characteristics.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) exhibits favorable handling properties in cements, being miscible in all proportions with rubber solvents.

Its addition at the solution stage eliminates the need for incorporation on the mixing mill during cement preparation.
The finished cement, when accelerated by ZDBCX, features a short pot-life, necessitating careful management during application.

In cements, ZDBCX showcases its effectiveness with recommended sulfur dosages and accelerant proportions.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) proves advantageous in dry natural rubber processing, offering a low-temperature acceleration option with the ability to be milled without decomposition.

Extrusion of rubber mixes containing Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) is achievable without scorching, provided appropriate precautions are observed.
Curing of rubber mixes containing ZDBCX can be accomplished in hot air at relatively low temperatures, adding to its versatility.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX) demonstrates its prowess as an accelerator in translucent SBR compounds, contributing to the curing of applications like footwear soles.

Synergistic combinations with sulphenamide or thiazole accelerators enhance ZDBCX's effectiveness in curing rubber compounds.
For optimal results, recommended levels of ZDBCX are specified for various rubber applications, ensuring precise and efficient performance.
Zinc N, N-di-n-butyldithiocarbamate/di-n-butylamine complex (ZDBCX)'s characteristics, spanning odor, appearance, stability, and reactivity, collectively position ZDBCX as a valuable component in the rubber industry.



PROPERTIES


Physical Properties:

Appearance: Light brown, slightly turbid liquid.
Odor: Faint smell of dibutylamine.
State: Liquid at room temperature.


Chemical Properties:

Chemical Formula: ((n-C4H9)2NCSS)2Zn/(n-C4H9)2NH
Solubility: Soluble in aliphatic and aromatic hydrocarbons; can be emulsified in water.
Purity: 97% minimum.



FIRST AID


Inhalation:

Move the affected person to fresh air.
If breathing is difficult, administer artificial respiration.
Seek medical attention.


Skin Contact:

Remove contaminated clothing.
Wash the affected area with plenty of water for at least 15 minutes.
If irritation persists, seek medical attention.
Contaminated clothing should be laundered before reuse.


Eye Contact:

Rinse eyes thoroughly with water for at least 15 minutes, holding eyelids open.
Seek immediate medical attention.
Remove contact lenses if easily removable after the initial rinse.


Ingestion:

Do not induce vomiting unless directed by medical personnel.
Rinse the mouth with water, but do not swallow.
Seek immediate medical attention.
If vomiting occurs and the person is conscious, keep the head lower than the chest to prevent aspiration.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves and safety goggles or a face shield.
Use respiratory protection if there is a risk of inhalation exposure.

Ventilation:
Work in a well-ventilated area, or use local exhaust ventilation to control airborne concentrations.

Avoidance of Contact:
Avoid skin contact and inhalation of vapors or dust.
Wash hands thoroughly after handling.

Prevention of Ingestion:
Do not eat, drink, or smoke in areas where the substance is handled.
Wash hands before eating, drinking, or smoking.

Handling Procedures:
Follow good industrial hygiene practices.
Use non-sparking tools to avoid ignition in potentially explosive atmospheres.

Storage of Containers:
Keep containers tightly closed when not in use to prevent contamination or evaporation.

Avoidance of Mixing:
Avoid mixing with incompatible materials. Consult the SDS for compatibility information.

Emergency Procedures:
Be familiar with emergency procedures, including the location of emergency exits and the use of emergency equipment.


Storage:

Storage Area:
Store in a cool, dry, and well-ventilated area.
Keep away from incompatible materials and sources of heat or ignition.

Temperature Control:
Store at temperatures recommended by the manufacturer.

Container Compatibility:
Use containers made of materials compatible with the substance.
Check for leaks or damage in storage containers.

Separation:
Store away from food, beverages, and animal feed.
Separate from incompatible materials.

Labeling:
Ensure that containers are properly labeled with the correct product information.

Access Control:
Limit access to storage areas to authorized personnel.

Handling Precautions:
Implement handling precautions based on the physical and chemical properties of the substance.

Special Considerations:
If applicable, follow any special storage conditions recommended by the manufacturer.



SYNONYMS


ZDBC
Zinc dibutyldithiocarbamate
Di-n-butyldithiocarbamic acid zinc salt complex with di-n-butylamine
ZBDCX
Zinc bis(di-n-butyldithiocarbamate)
ZINC OMADINE
Zinc omadine is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.
Zinc omadine is a coordination complex of zinc.
Zinc omadine is chemical compound used as an antifungal and antibacterial agent.
Zinc omadine is a chemical with antifungal and antimicrobial properties.


CAS Number: 13463-41-7
EC Number: 236-671-3
Chemical formula: C10H8N2O2S2Zn


Zinc omadine is a chemical among the pyrithione complex compounds of Zinc Bromide.
Zinc omadine, which has many names, was first reported in the 1930s.
Zinc omadine features two pyridine-derived chelating ligands bound to zinc via oxygen and sulfur atoms.
Zinc omadine was first described in the 1930s.


Zinc omadine is a zinc complex of pyrithione.
Zinc omadine possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc omadine dispersion is a higher viscosity, fine particle dispersion specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


In particular, soluble iron can react with the Zinc omadine active ingredient and a grayblue color may develop.
By using Zinc omadine Dispersion in these formulations, reaction of iron with the zinc pyrithione component is eliminated.
The Zinc omadine Dispersion is registered with the United States Environmental Protection Agency.
While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc omadine has been reported for decades.


Zinc omadine is not shown to have any significant estrogenic activity according to the in vivo and in vitro assays.
Zinc omadine is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.
We do not recommend long-term storage for the solution, please use it up soon.


Zinc omadine is an aromatic zinc compound.
When used as an active drug ingredient, the established name for Zinc omadine is Pyrithione Zinc.
Zinc omadine is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Zinc omadine products are highly active, broad spectrum antimicrobial agents that are registered around the world for use in both personal care as well as industrial product applications.


Zinc omadine fungicide-algaecide is the active ingredient in some of the leading antidandruff shampoo products around the world, and its proven combination of efficacy and safety-in-use has made it the world's leading anti-dandruff agent for more than 30 years.
Zinc omadine fungicide-algaecide is listed in the FDA Final Monograph on Dandruff and Seborrheic Dermatitis as a Category I substance (i.e. generally recognized as safe and effective).


Zinc omadine products are available in Industrial and Cosmetic grades, and in powder and in dispersion forms.
In the U.S., Zinc omadine products are approved for use by the EPA and allowed by the FDA.
Zinc omadine fungicide-algaecide is the zinc complex of pyrithione.
Zinc omadine, the zinc salt of pyrithione (pyridine-2-thiol-1-oxide), has recently been reclassified.



USES and APPLICATIONS of ZINC OMADINE:
Zinc omadine acts as an anti-dandruff and antimicrobial agent. Suitable for personal cleansing with bar soaps.
Zinc omadine is an effective bactericidal and/ or bacteriostatic active against specific bacteria linked to odor.
Zinc omadine is used in anti-dandruff shampoos, rinse-off personal cleansing and other hair care products.


Zinc omadine is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc omadine products have been providing dandruff relief and improved scalp health for over 50 years.
Zinc omadine is used as anti-dandruff agent and bactericide in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.


Zinc omadine is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Zinc omadine has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
Zinc omadine is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Zinc omadine is an effective broad spectrum bio-cide for the preservation of products against spoilage from fungi, yeasts, algae and bacteria.
Zinc omadine is the technical grade active substance more commonly named zinc pyrithione.
Zinc omadine offers antimicrobial protection in the wet and in the dry film state.
Zinc omadine is used in both personal care and industrial product applications.


The recommended applications of Zinc omadine are water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc omadine has a broad antimicrobial spectrum of efficacy against various microorganisms such as bacteria, fungi, and algae.
The outstanding properties of Zinc omadine with regard to effectiveness and compatibility are widely used.
Zinc omadine is a preservative against bacteria, fungi, and yeast.


Zinc omadine is useful in gels, creams, heavy lotions, and talcum powder.
Zinc omadine antimicrobial products are highly active, broad-spectrum biocides used in personal care as well as industrial applications.
Zinc omadine products are approved for OEKO-TEX standard 100, classes I-IV.


Zinc omadine is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.
Zinc omadine, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.


In the crystalline state, Zinc omadine exists as a centrosymmetric dimer.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc omadine is used to treat dandruff and seborrheic dermatitis.
Zinc omadine is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc omadine mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth 1.


Due to low solubility, Zinc omadine released from the topical formulations is deposited and retained relatively well onto the target skin surfaces 2.
These properties include conductivity, corrosion resistance, density, hardness, and impact resistance.
First of all, metal sheets are thermal conductors.


Therefore, sheets with low conductivity are ideal for insulation, while those with high conductivity are used in applications like refrigeration.
Zinc omadine is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Secondly, Zinc omadine is essential to consider the density of the metal plate because it will determine how much a component of a specific size will weigh.
This property is vital in the aerospace and automotive industry, where weight matters.
Moreover, corrosion resistance of a zinc omadine is also essential.


This is because some metal sheets can withstand harsh environmental conditions while others cannot.
Therefore, the sheet you select should fit your needs.
The other property to consider impacts resistance.
If the sheet is likely to be subjected to vigorous collision and shock, you need to pick one with high resistance.


Furthermore, metal hardness also matters because it determines the ability of a sheet to resist the pressure exerted on its surface.
There are three types of hardness; Rockwell, Brinell, and Vickers.
Therefore, the metal plate you select should have the hardness you require.
Antifungal, antibacterial and antiseborrheic agent is used in many shampoos and hair creams.


Zinc omadine, also commonly known as zinc pyrithione, has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc omadine can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.
As the name suggests, Zinc omadine is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.


Zinc omadine's properties are inhibited in formulations containing edta and products containing nonionic chemicals.
This is because chelation or anti-extraction property occurs and the chelated complexes formed do not dissolve.
Zinc omadine is an antifungal and antimicrobial agent that blocks the transport of membranes.
Zinc omadine is the chemical that prevents the formation of mold caused by gram positive and gram negative bacteria in the hair.


In the cosmetic industry, Zinc omadine is used in the production of shampoos that strengthen and rejuvenate hair and prevent graying of hair.
Zinc omadine is used to prevent the formation of bacteria in the paint.
Zinc omadine is used to destroy such fungi in order to prevent the formation of dandruff fungi in the hair.
Zinc omadine also has low irritant properties.


These boats are coated in order to prevent the adhesion of microorganisms that damage the boats and affect their performance.
Zinc omadine is used as a biocide in the dyes used in these coatings .
Zinc omadine prevents the formation of fungi by interfering with the primary proton pump.
Blackmail is an important component for regulating the keratin structure.


Zinc omadine is traded using the range of 1%-2%.
Zinc omadine prevents the formation of bacteria and algae in outdoor paints.
Zinc omadine is a coordination complex of zinc and pyrithione that is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.


-Uses of Zinc omadine:
*Creams and lotions
*Hair products (Head & Shoulders)
*Shampoos


-Cosmetic Uses of Zinc omadine:
*antidandruff agents
*antiseborrhoeic agents
*hair conditioning
*preservatives


-Medical:
Zinc omadine is best known for its use in treating dandruff and seborrheic dermatitis.
Zinc omadine also has antibacterial properties and is effective against many pathogens from the streptococcus and staphylococcus class.
Zinc omadine's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atypical dermatitis, tinea, and vitiligo.
Zinc omadine is approved for over-the-counter topical use in the United States as a treatment for dandruff.
Zinc omadine is the active ingredient in several anti-dandruff shampoos such as Head & Shoulders.
However, in its industrial forms and strengths, it may be harmful by contact or ingestion.


-In paint:
Due to its low solubility in water (8 ppm at neutral pH), Zinc omadine is suitable for use in outdoor paints and other products that provide protection against mildew and algae.
Zinc omadine is an effective algaecide.
Zinc omadine is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc omadine is used in latex paints and the water contains high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed.
Zinc omadine's decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight.


-In sponges:
Zinc omadine is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.


-Zinc omadine shampoo:
Zinc omadine shampoo is found in many common anti-dandruff shampoos.
Zinc omadine is antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Applications of Zinc omadine:
*Beauty & Care
Hair Care, Treatment Products, Skin Care


-Hair Care Applications:
*Anti-Dandruff Products
*Hair Conditioner
*Shampoos & Rinses


-Zinc omadine cream:
Seborrheic dermatitis often affects the scalp, but Zinc omadine can also cause rough, scaly patches on the skin.
Zinc omadine cream is used to treat seborrheic dermatitis or psoriasis on the body.
For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc omadine followed by a moisturizer.
You can also use the cream daily by applying it in a thin layer to the affected area.


-Zinc omadine face wash:
Zinc omadine face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc omadine can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc omadine may help clear acne.


-Medicine:
Zinc omadine can be used to treat dandruff and seborrhoeic dermatitis.
Zinc omadine also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc omadine's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint:
Because of its low solubility in water (8 ppm at neutral pH), Zinc omadine is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc omadine is an algaecide.
Zinc omadine is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc omadine is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc omadine is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.


-Clothing:
A process to apply Zinc omadine to cotton with washable results was patented in the United States in 1984.
Zinc omadine is used to prevent microbe growth in polyester.
Textiles with applied Zinc omadine protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.



FEATURES AND BENEFITS OF ZINC OMADINE:
*Anti-Bacterial
*Anti-Dandruff
*Anti-Fungal
*Antimicrobial
*Chelating
*De-Odorizing
*Odor Masking
*Scalp Protection Effect
*Sebum Control
*Stress Reducing
*Substantivity
*Suitable for Oily Skin



BENEFITS OF ZINC OMADINE:
*Outstanding durability and effectiveness
*Broad spectrum of efficacy against bacteria, and fungi
*Long-lasting material protection, e.g., against rotting
*High wash resistance
*Ease of application in the usual application processes
*Readily combined with many textile effects, e.g., fluorocarbons
*Can be added to a dye bath



COSMETIC INGREDIENTS FUNCTIONS OF ZINC OMADINE:
*Anti-Dandruff Agent
*Antimicrobial Agent
*Bacteriostatic Agent
*Fungistatic Agent



STRUCTURE OF THE ZINC OMADINE:
Zinc omadine ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc omadine exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.
In solution, however, the dimers dissociate via scission of one Zn-O bond.



ZINC OMADINE IS PARTICULARLY EFFECTIVE AS A SINGLE ACTIVE DRY-FILM PRESERVATIVE FOR:
– Architectural and industrial paint and coatings.
– Construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds.
– Building materials including ceilings, ceiling tiles, walls and internal partitions.
– Textiles including apparel and home textiles.
– Thermoplastic polymers such as PVC, silicone, polyolefin, polyurethane and acrylics.
– Plastics applications for the control of mildew and bacteria in carpeting, carpet underlay, cushion and mattress foam, athletic flooring and mats, components of footwear and sponges.



KEY PRODUCT ATTRIBUTES FOR ZINC OMADINE:
Relieves flaking symptoms of dandruff
Targets scalp with a slow release for highest efficacy
Effective dispersion because it is not soluble
Enhances substantivity to the skin and hair
Maintains efficacy over long-term use without resistance



WHAT ARE ZINC OMADINE'S PHYSICAL AND CHEMICAL PROPERTIES?
Zinc omadine is in the form of a cloudy white powder.
Zinc omadine's Melting Point is about 240 °C.
Zinc omadine's density at 25 °C is 1.782 g/cm³.
Zinc omadine emits toxic fumes when heated with heat.
These emit fumes of nitrogen oxides, zinc oxide and sulfur oxide.
Zinc omadine has low resolution. Polyethylene Glycol (PEG400) has a solubility of 2g/kg.
The pH range of Zinc omadine is between 4.5 and 9.5.



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN ZINC OMADINE?
*Cream
*Household Products
*Shampoos



WHERE IS ZINC OMADINE FOUND?
Zinc omadine is an antibacterial and antifungal agent.
Zinc omadine is found in dandruff shampoo and cosmetic products for the treatment of skin problems.



MECHANISM OF ZINC OMADINE:
Zinc omadine's antifungal effect most likely lies in the ability of an un-ionized pyrithione molecule to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.
Fungi are capable of inactivating pyrithione in low concentrations.



MECHANISM OF ACTION OF ZINC OMADINE:
Zinc omadine's antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



HOW IS ZINC OMADINE PRODUCED?
Production of Zinc omadine A compound consisting of 2-Bromopyridine N-oxide or 2-chloropyridine group is selected.
To this selected aqueous solution, one of the Sodium Hydrosulfite, sodium carbonate and sodium hydroxide bases is added.
In the base addition process here, the temperature ranges from 20 °C to 65 °C.
The sodium pyrithione obtained in the production process is increased from 75 °C to 105 °C and reacted with a zinc salt.
The zinc salt used here is zinc chloride (ZnCl 2 ) or zinc sulfate (ZnSO 4 ) .



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE:
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C - OECD Test Guideline 102
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C - OECD Test Guideline 105
Partition coefficient: n-octanol/water: log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
Appearance: beige fine granules (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 240.00 °C. @ 760.00 mm Hg (est)
Boiling Point: 350.20 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 0.000091 mmHg @ 25.00 °C. (est)
Flash Point: 330.00 °F. TCC ( 165.60 °C. ) (est)
logP (o/w): -0.900 (est)
Soluble in: water, 4.876e+005 mg/L @ 25 °C (est)

Water Solubility: 0.068 mg/mL
logP: 0.6
logP: 0.2
logS: -3.7
pKa (Strongest Acidic): 6.84
pKa (Strongest Basic): 0.66
Physiological Charge: -1
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 0
Polar Surface Area: 26.94 Å2
Rotatable Bond Count: 0
Refractivity: 31.64 m3·mol-1
Polarizability: 11.91 Å3
Number of Rings: 2
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule:No



FIRST AID MEASURES of ZINC OMADINE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
Do not inhale substance/mixture.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.



STABILITY and REACTIVITY of ZINC OMADINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
bis(2-pyridylthio)zinc 1,1´-dioxide
bis-(1-hydroxy-2(1H)-pyridinethionato-O,S)zine
De-Squaman
Vancide ZP
Zinc pyrithione
Zinc pyridinethione
Zinc omadine
Pyrithion-Zink
Zinc omadine
Zinc pyridinethione
Zinc Pyrithione
Zinc-2-pyridinethione-1-oxide
Zincpolyanemine
Zinc omadine
bis(2-pyridylthio)zinc 1,1'-dioxide
bis-(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc
De-Squaman; Vancide ZP
Zinc pyridinethione
Zinc omadine
Zinc pyridine-2-thiol-1-oxide
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-
bis(2-pyridylthio)zinc, N,N'-dioxide
bis(1-hydroxy-2(1H)-pyridinethionato)zinc
2-pyridinethiol-1-oxide, zinc salt
vancide p
2-mercaptopyridine-1-oxide zinc salt
zinc 1-hydroxy-2-pyridine-thione
omadine zinc
OM-1563
Pyridinethiol-1-oxide, zinc salt
Zinc-pyrion
Zinc 1-hydroxypyridine-2-thione
Zinc 2-mercaptopyridine-N-oxide
Zinc 2-pyridinethiol-1-oxide
Zinc polyanemine
Zinc PT
Zinc, bis(2-pyridylthio)-, N,N,'-dioxide
ZNPT
Pyrithione zinc.
Zinc pyridinethione
2-Mercaptopyridine N-Oxide Zinc Salt
Mercaptopyridine N-oxide zinc salt
1-Hydroxypyridine-2-thione zinc salt
Bis(2-pyridylthio) Zinc 1,1'-Dioxide
2-Pyridinethiol 1-Oxide Zinc Salt
bis(N-oxopyridine-2-thionato)zinc(II)
Zinc omadine
Zinc Pt
Zinc Pyridine-2-thiol,1-oxide
Zinc bis(2-pyridylthio)-N-oxide
2-mercaptopyridine 1-oxide zinc salt
Zincpolyanemine
Zinc Omadine
2-Mercaptopyridine 1-oxide Zinc Salt
2-Pyridinethiol 1-oxide Zinc Salt
2-Pyridinethiol N-oxide Zinc Salt
2-Pyridylthiol-1-oxide Zinc Salt
AF-Z
BC-J
Biocut ZP
Bis(1-hydroxy-2(1H)-pyridinethionato)zinc
Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc
Bis(2-pyridinethiol 1-oxide)zinc
Clean-Bio ZP
Danex
Marukacide YP-DP
Microban Additive ZO 1
Microban Z 01
NSC 290409;
Niccanon SKT
Niccanon ZP
OM 1563
Omadine Zinc
Pyrithione zinc
SR-A 103
Sanaizol 200
Sanitized TH 22-27
Sanitized TH 27-24BT
Zinc Omacide ZOE
Zinc Omadine
Zinc Omadine ZOE
(T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc
(T-4)-bis(1-hydroxy-2(1H)- pyridinethionato-O,S)zinc
1-hydroxypyridine-2-thione
2(1H)-Pyridinethione, 1-hydroxy-, zinc complex
2-Mercaptopyridine 1-oxide zinc salt
2-Pyridinethiol-1-oxide, zinc salt
2C5H4NOS.Zn
BC-J
Biocut ZP
Bis(1-hydroxy-2(1H)-pyridinethionato)zinc
Bis(2-pyridinethiol-1-oxide)zinc
Bis(2-pyridylthio)zinc 1,1'-dioxide
Breck One Dandruff Shampoo
Evafine P 50
FSB 8332
Finecide ZPT
HEAD & SHOULDERS CONDITIONER
HEAD AND SHOULDERS CONDITIONER
Head and Shoulders
Hokucide ZPT
Mercaptopyridine-N-oxide
Niccanon SKT
OM-1563
Omadine Zinc
Piritionato cincico
Pyrithione zincique
Pyrithionum zincicum
Tomicide Z 50
Tomicide ZPT 50
Top Brass
Vancide P
Vancide ZP
Wella Crisan
ZNP bar
ZPT
Zinc - pyrion
Zinc 1-hydroxy-2-pyridinethione
Zinc 2-mercaptopyridine N-oxide
Zinc 2-pyridinethiol-1-oxide
Zinc Omadine
Zinc bis(2-pyridylthio)-N-oxide
Zinc pt
Zinc pyrethion
Zinc pyridine-2-thiol 1-oxide
Zinc pyridine-2-thiol-1-oxide
Zinc pyridinethione;Zinc, bis(1-(hydroxy-kappaO)-2(1H)-pyridinethionato-kappaS2)-, (T-4)-
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)- (8CI)
Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4)-
Zinc, bis(2-pyridinylthio)-, N,N'-dioxide
Zinc, bis(2-pyridylthio)-, 1,1'-dioxide
Zinc, bis(2-pyridylthio)-, N,N'-dioxide
Zinc, bis[1-(hydroxy-.kappa.O)-2(1H)-pyridinethionato-.kappa.S2]-, (T-4)-
Zinci pyrithionum
Zincpolyanemine
Zn - pyrion
ZnPT
bis(N-oxopyridine-2-thionato)zinc (II)
zinc bis(2-thioxopyridin-1(2H)-olate)

ZINC OMADINE (ZnPT, ZINC PYRITHIONE)
Zinc Omadine (ZnPT, Zinc Pyrithione) is a “coordination complex” of zinc and pyrithione.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a fine beige granules.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the active ingredient in several anti-dandruff shampoos.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn



Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT, Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc,



Zinc Omadine (ZnPT, Zinc Pyrithione) can restrain and sterilize eight moulds, including black mold,aspergillus flavus, aspergillus versicolor,penicillium citrinum, paecilomium varioti bainier,trichoderma viride, chaetomium globasum and cladosporium herbarum; five bacteria, such as E.coli, staphylococcus aureus, bacillus subtilis,bacillus megaterium and pseudomonas fluorescence as well as two yeast fungi which are distillery yeast and bakers’ yeast.


Zinc Omadine (ZnPT, Zinc Pyrithione) also works against dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a potent antifungal agent in a water suspension format.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and bacterial (gram-positive & gram-negative).


Zinc Omadine (ZnPT, Zinc Pyrithione) is a “coordination complex” of zinc and pyrithione.
Zinc Omadine (ZnPT, Zinc Pyrithione) is one of the active ingredients we use in our shampoos.
On the 4th March 2020, the Scientific Committee on Consumer Safety concluded that Zinc Omadine (ZnPT, Zinc Pyrithione) is safe when used as an anti-dandruff in rinse-off hair products in a concentration of maximum 1%.


Being subject to several safety evaluations, Zinc Omadine (ZnPT, Zinc Pyrithione) was previously found safe as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.
This came as a result of a safety dossier that was submitted by Cosmetics Europe to demonstrate the safety of Zinc Omadine (ZnPT, Zinc Pyrithione) as anti-dandruff in rinse-off hair products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a fine beige granules.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.


Although the exact mechanism of action remains to be fully elucidated, Zinc Omadine (ZnPT, Zinc Pyrithione) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.
Zinc Omadine (ZnPT, Zinc Pyrithione) has also started to be used as an active substance in boat hull paint.


Topical Zinc Omadine (ZnPT, Zinc Pyrithione) appears to be a safe and effective treatment for psoriasis.
An aerosol preparation of Zinc Omadine (ZnPT, Zinc Pyrithione) (0.25%) in a vehicle containing isopropyl myristate appears to be a safe and effective treatment for psoriasis.


Zinc Omadine (ZnPT, Zinc Pyrithione) was found to be negative in mutation tests in bacteria and Chinese hamster ovary cells.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the active ingredient in several anti-dandruff shampoos.


Zinc Omadine (ZnPT, Zinc Pyrithione) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.
UV light slowly breaks down Zinc Omadine (ZnPT, Zinc Pyrithione), providing years of protection even in direct sunlight.


Zinc Omadine (ZnPT, Zinc Pyrithione) is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is approved for over-the-counter topical use in the United States as a treatment for dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the active ingredient in several anti-dandruff shampoos.


The effectiveness of Zinc Omadine (ZnPT, Zinc Pyrithione) is well-established, but as with many modern medicines that have evolved from time-tested remedies, the way the drug actually works is less clear.
In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.


Zinc Omadine (ZnPT, Zinc Pyrithione) has been the top choice among anti-dandruff agents around the world for more than 30 years.
Zinc Omadine (ZnPT, Zinc Pyrithione)'s potent action against Pityrosporum Ovale, the primary culprit for dandruff, ensures healthy, dandruff-free hair.
Unlike other treatments, Zinc Omadine (ZnPT, Zinc Pyrithione) also keeps fungal infections at bay, resulting in a scalp that's not just visibly clean, but truly healthy.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a chemical compound of zinc.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an antifungal and antibacterial agent.
Zinc is a metallic element with the atomic number 30.


If Zinc Omadine (ZnPT, Zinc Pyrithione) is used as a preservative in cosmetic and hygiene products the total proportion can be no more than 0,5 %.
Similarly, no chromosomal aberration was observed in human lymphocytes incubated in vitro in the presence of Zinc Omadine (ZnPT, Zinc Pyrithione) or in lymphocytes harvested from monkeys.


The mineralization of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-on (DCOI) and Zinc Omadine (ZnPT, Zinc Pyrithione) was examined in laboratory tests with marine coastal sediments.
Zinc Omadine (ZnPT, Zinc Pyrithione) has been used as a booster biocide in antifouling paints of ships.


For its environmental risk assessment, a direct analyzing technique of Zinc Omadine (ZnPT, Zinc Pyrithione) has been developed using HPLC-MS without transforming to other substances.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an antifungal and antibacterial agent.


Zinc Omadine (ZnPT, Zinc Pyrithione) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Omadine (ZnPT, Zinc Pyrithione) works against the viability of bacteria and fungi.



USES and APPLICATIONS of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Zinc Omadine (ZnPT, Zinc Pyrithione) is known for its ability to control and prevent dandruff and other scalp conditions caused by the overgrowth of certain microorganisms.
Additionally, Zinc Omadine (ZnPT, Zinc Pyrithione) can be found in skincare products to address other skin conditions like acne and seborrheic dermatitis due to its antimicrobial properties.


Zinc Omadine (ZnPT, Zinc Pyrithione), also known as pyrithione zinc, has antibacterial, antimicrobial, and antifungal qualities that can help cure acne, scalp psoriasis, and seborrheic dermatitis (also known as dandruff).
Zinc Omadine (ZnPT, Zinc Pyrithione) is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.


In recent years, there have been some regulatory updates concerning the use of Zinc Omadine (ZnPT, Zinc Pyrithione) in personal care and cosmetic products in Asia and globally.
Zinc Omadine (ZnPT, Zinc Pyrithione) is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of zinc.
Additionally, Zinc Omadine (ZnPT, Zinc Pyrithione) aids in controlling sebum production, contributing to a healthier scalp environment.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.


Zinc Omadine (ZnPT, Zinc Pyrithione) with a high concentration of 48%.
Zinc Omadine (ZnPT, Zinc Pyrithione) is a biocide that effectively inhibits the growth of fungi and bacteria, making it a popular ingredient in anti-dandruff shampoos and scalp treatments.


Zinc Omadine (ZnPT, Zinc Pyrithione) can stop yeast from growing, which is a major contributor to dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione), as its name implies, is a chemical compound made from zinc and is utilized in a number of hair and skin care products.
Moreover, Zinc Omadine (ZnPT, Zinc Pyrithione) is also allowed in a concentration up to 0.1% in leave-on hair products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.


Zinc Omadine (ZnPT, Zinc Pyrithione) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.


Zinc Omadine (ZnPT, Zinc Pyrithione) is very effective against a wide variety of pathogenic bacteria/fungus.
Sponges: Zinc Omadine (ZnPT, Zinc Pyrithione) is an antibacterial treatment for household sponges, as used by the 3M Corporation.
Zinc Omadine (ZnPT, Zinc Pyrithione) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


In the cosmetic industry, zinc and zinc salts are used in various products.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) has long been used as anti-dandruff agent and widely used in various popular shampoos.


Zinc Omadine (ZnPT, Zinc Pyrithione) is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Omadine (ZnPT, Zinc Pyrithione) can effectively prevent precipitation and double the antimicrobial effect.
Shampoo for dandruff, Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation.


Zinc Omadine (ZnPT, Zinc Pyrithione) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Omadine (ZnPT, Zinc Pyrithione) has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus,playing a role in dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.


As an anti-mildew agent, Zinc Omadine (ZnPT, Zinc Pyrithione) also has some applications on fabrics.
Therefore, Zinc Omadine (ZnPT, Zinc Pyrithione) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


The optimum process conditions were determined by single-factor and orthogonal tests.
The process parameters of cotton fabrics were: Zinc Omadine (ZnPT, Zinc Pyrithione) mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Omadine (ZnPT, Zinc Pyrithione) mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Omadine (ZnPT, Zinc Pyrithione) has unique advantages in environmental friendliness and sterilization persistence.
Therefore, Zinc Omadine (ZnPT, Zinc Pyrithione) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.


Due to its low solubility in water (8 ppm at pH 7), Zinc Omadine (ZnPT, Zinc Pyrithione) is suitable for outdoor coatings and other products that protect against mold and algae.
In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) is an effective algaecide.


Zinc Omadine (ZnPT, Zinc Pyrithione) anti-mildew agent can play the best anti-mildew effect.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an additive to protect paints (such as industrial and marine) against microbe (algal, fungal and bacterial) and crustacean growth.


Zinc Omadine (ZnPT, Zinc Pyrithione) acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.
Zinc Omadine (ZnPT, Zinc Pyrithione) can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.


For shampoo to remove dandruff, Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit the growth of gram-positive and negative bacteria and mold.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.
Zinc Omadine (ZnPT, Zinc Pyrithione) is mainly used in cosmetics, shampoos, and skin care products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is widely used as a fungicide for paints and plastics.
Zinc Omadine (ZnPT, Zinc Pyrithione) can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.


Zinc Omadine (ZnPT, Zinc Pyrithione) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Omadine (ZnPT, Zinc Pyrithione) products have been providing dandruff relief and improved scalp health for over 50 years.


Zinc Omadine (ZnPT, Zinc Pyrithione) is thus used in dandruff shampoos and also in various cosmetics and products against various skin problems.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used as an antifungal and antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit the growth of yeast, which is a main factor in dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


Zinc Omadine (ZnPT, Zinc Pyrithione) also known as pyrithione zinc, pyrithionium zinc, olmaitin zinc, this zinc complex as early as in the 1930s was synthesized and used as an external antifungal agent or antibacterial agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is white to yellow crystalline powder at room temperature.


Zinc Omadine (ZnPT, Zinc Pyrithione) is slight characteristic odor.
Zinc Omadine (ZnPT, Zinc Pyrithione) is insoluble in water.
Zinc pyrazide forms insoluble deposits with cationic and non-ionic surfactants and is unstable to light and oxidants, and to acids and bases at higher temperatures.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.
In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) is also used as a cosmetic preservative, oil agent, and paint biocide.


As a fungicide for products such as coatings and plastics, Zinc Omadine (ZnPT, Zinc Pyrithione) is also widely used.
Anti-dandruff agent uses of Zinc Omadine (ZnPT, Zinc Pyrithione): Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)
Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Omadine (ZnPT, Zinc Pyrithione): Skin care (creams & lotions), Foot creams and Talcs


Rinse-off body wash products uses of Zinc Omadine (ZnPT, Zinc Pyrithione): Bar Soaps, Body wash, Bubble bath
Zinc Omadine (ZnPT, Zinc Pyrithione) is a coordination complex of zinc.
Although the exact mechanism of action remains to be fully elucidated, Zinc Omadine (ZnPT, Zinc Pyrithione) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.


In addition, Zinc Omadine (ZnPT, Zinc Pyrithione) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.
As the name suggests, Zinc Omadine (ZnPT, Zinc Pyrithione) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.
Zinc Omadine (ZnPT, Zinc Pyrithione) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.


In the pesticide field, Zinc Omadine (ZnPT, Zinc Pyrithione) is used mainly to control apple leaf curl and scab, among others.
Zinc Omadine (ZnPT, Zinc Pyrithione)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.


Zinc Omadine (ZnPT, Zinc Pyrithione)’s an ingredient in skincare and hair products because of its antibacterial, antimicrobial, and antifungal properties.
Zinc Omadine (ZnPT, Zinc Pyrithione) helps prevent the dandruff-causing microbe, Malassezia globosa, from making the substances that irritate your scalp.
The cosmetic ingredient Zinc Omadine (ZnPT, Zinc Pyrithione) is frequently used in the formulation of hair conditioners, shampoos, face powders, cleansing products, eyeliners and skin care products.


Zinc Omadine (ZnPT, Zinc Pyrithione) is currently regulated as a preservative in rinse-off products (with the exception of oral hygiene products) in a concentration of up to 0.5% in general products and up to 1.0% in hair products.
Zinc Omadine (ZnPT, Zinc Pyrithione) is one of the zinc salts frequently used in hair conditioners, shampoos, face powders, cleaning products, eye pencils, cleaning and skin care products.


It is active against the bacteria E. coli, Zinc Omadine (ZnPT, Zinc Pyrithione) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.
Formulations containing Zinc Omadine (ZnPT, Zinc Pyrithione) have been used in the treatment of dandruff.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a preservative against bacteria, fungi, and yeast.
Zinc Omadine (ZnPT, Zinc Pyrithione) is unstable in light and in the presence of oxidizing agents.
Zinc Omadine (ZnPT, Zinc Pyrithione) is useful in gels, creams, heavy lotions, and talcum powder.


Zinc Omadine (ZnPT, Zinc Pyrithione) is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.
The chemical formula of Zinc Omadine (ZnPT, Zinc Pyrithione) is C10H8N2O2S2Zn.


Zinc Omadine (ZnPT, Zinc Pyrithione) is anticipated to be ingested in significant quantities during the production of grooming items such soap and shower products, disinfectants, and antiseptic products.
As a result, Zinc Omadine (ZnPT, Zinc Pyrithione)'s consumption is predicted to increase at a significant rate, expanding the market size.


Zinc Omadine (ZnPT, Zinc Pyrithione) is used Shampoo for dandruff.
Zinc Omadine (ZnPT, Zinc Pyrithione) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.


Zinc Omadine (ZnPT, Zinc Pyrithione) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Omadine (ZnPT, Zinc Pyrithione) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .


-Paint uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Omadine (ZnPT, Zinc Pyrithione) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an algaecide.

Zinc Omadine (ZnPT, Zinc Pyrithione) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Omadine (ZnPT, Zinc Pyrithione) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Omadine (ZnPT, Zinc Pyrithione) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.


-Clothing uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
A process to apply Zinc Omadine (ZnPT, Zinc Pyrithione) to cotton with washable results was patented in the United States in 1984.
Zinc Omadine (ZnPT, Zinc Pyrithione) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Omadine (ZnPT, Zinc Pyrithione) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Shampoo uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Zinc Omadine (ZnPT, Zinc Pyrithione) shampoo is found in many common anti-dandruff shampoos.
Zinc Omadine (ZnPT, Zinc Pyrithione) is antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Cream uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Seborrheic dermatitis often affects the scalp, but Zinc Omadine (ZnPT, Zinc Pyrithione) can also cause rough, scaly patches on the skin.
Zinc Omadine (ZnPT, Zinc Pyrithione) cream is used to treat seborrheic dermatitis or psoriasis on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Omadine (ZnPT, Zinc Pyrithione) followed by a moisturizer.
You can also use the cream daily by applying it in a thin layer to the affected area.


-Face wash uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Zinc Omadine (ZnPT, Zinc Pyrithione) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Omadine (ZnPT, Zinc Pyrithione) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Omadine (ZnPT, Zinc Pyrithione) may help clear acne.


-Medicine uses of Zinc Omadine (ZnPT, Zinc Pyrithione):
Zinc Omadine (ZnPT, Zinc Pyrithione) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Omadine (ZnPT, Zinc Pyrithione) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Omadine (ZnPT, Zinc Pyrithione)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.



ORIGIN OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Zinc Omadine (ZnPT, Zinc Pyrithione) is synthesized through a multistep chemical process. Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Omadine (ZnPT, Zinc Pyrithione) undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Omadine (ZnPT, Zinc Pyrithione) is then filtered, washed, and dried to obtain a fine powder.



ALTERNATIVES OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
*KETOCONAZOLE,
*SELENIUM SULFIDE



WHAT IS ZINC OMADINE (ZnPT, ZINC PYRITHIONE) USED FOR?
Zinc Omadine (ZnPT, Zinc Pyrithione) is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, Zinc Omadine (ZnPT, Zinc Pyrithione) effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Omadine (ZnPT, Zinc Pyrithione) also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Omadine (ZnPT, Zinc Pyrithione)’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



WHAT DOES ZINC OMADINE (ZnPT, ZINC PYRITHIONE) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



SHAMPOO ZINC OMADINE (ZnPT, ZINC PYRITHIONE) MARKET: OVERVIEW
Zinc Omadine (ZnPT, Zinc Pyrithione), also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by Zinc Omadine (ZnPT, Zinc Pyrithione).
Zinc Omadine (ZnPT, Zinc Pyrithione), as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Omadine (ZnPT, Zinc Pyrithione) shampoo.
Zinc Omadine (ZnPT, Zinc Pyrithione) is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



STRUCTURE OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Omadine (ZnPT, Zinc Pyrithione) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via scission of one Zn-O bond.
Zinc Omadine (ZnPT, Zinc Pyrithione) was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



ADVANTAGES OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Zinc Omadine (ZnPT, Zinc Pyrithione) helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Zinc Omadine (ZnPT, Zinc Pyrithione) is used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



ZINC OMADINE (ZnPT, ZINC PYRITHIONE) THE WORLD'S NUMBER ONE ANTI-DANDRUFF INGREDIENT?
Zinc Omadine (ZnPT, Zinc Pyrithione), coal tar, salicylic acid… the list goes on.
There are so many ways to treat dandruff – but what makes Zinc

Dandruff treatment can take one of two approaches:
*treat the symptoms – this is designed to address the visible symptoms like flakes or inflammation.
However, theunderlying cause of dandruff is still working away.

*tackle the cause – here you get to the root of the problem.
By tackling the cause you can achieve more completerelief and prevent the symptoms from reappearing, so it’s a good long-term solution.
Meet the products that just treat the symptoms of dandruff

Those dandruff treatments that merely work on the symptoms include coal tar and salicylic acid.
Coal tar helps to control the skin’s reaction to scalp irritants formed as the microbe Malassezia globosa breaks down naturaloils on the scalp.
So while you might not experience quite as much irritation, those substances are still being produced at the same rate... and could still damage your scalp.

Salicylic acid acts on the actual flakes.
It is designed to help break the bonds between dead skin cells to make them easier to washoff.

But just like coal tar, salicylic acid doesn’t tackle the underlying cause of your itch, irritation, or flakes – so it’s lesseffective against dandruff.
In fact, in clinical testing these products are far less effective at treating flakes than 1% Zinc Omadine (ZnPT, Zinc Pyrithione) shampoos.



FUNCTIONS OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
*To combat dandruff,
*To control sebum production,
*Zinc Omadine (ZnPT, Zinc Pyrithione) helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Omadine (ZnPT, Zinc Pyrithione) prevents the development of microorganisms in cosmetic products.
*According to the SCCS (Scientific Committee on Consumer Safety) opinion published in 2014 and 2018, Zinc Omadine (ZnPT, Zinc Pyrithione) was found safe to use as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.



WHERE IS ZINC OMADINE (ZnPT, ZINC PYRITHIONE) FOUND?
Zinc Omadine (ZnPT, Zinc Pyrithione) is an antibacterial and antifungal agent.
Zinc Omadine (ZnPT, Zinc Pyrithione) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Omadine (ZnPT, Zinc Pyrithione) is an antibacterial and antifungal agent.

Zinc Omadine (ZnPT, Zinc Pyrithione) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Omadine (ZnPT, Zinc Pyrithione) is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Omadine (ZnPT, Zinc Pyrithione) products have been providing dandruff relief and improved scalp health for over 50 years.



FUNCTIONS AND PROPERTIES OF
*Mechanism of Pyrithione-Induced Membrane
*Depolarization in Neurospora crassa
*A clinically controled prospective study with histology
*Embryotoxicity of the antifouling biocide zinc pyrithione to sea urchin (Paracentrotus lividus) and mussel (Mytilus edulis)



ZINC OMADINE (ZnPT, ZINC PYRITHIONE), A BETTER LONG-TERM SOLUTION?
Zinc Omadine (ZnPT, Zinc Pyrithione) is used easily the best way to treat dandruff and keep it away for good is to use an anti-dandruff shampoo with an activeingredient that tackles the root cause of dandruff.

That’s where Zinc Omadine (ZnPT, Zinc Pyrithione) comes in.
Zinc Omadine (ZnPT, Zinc Pyrithione) both removes and helps prevent the formation of scalp irritants, to keep your scalphealthy and comfortable.

With smaller particles, the dandruff-fighting active can:
*give longer lasting protection – because it’s smaller, Zinc Omadine (ZnPT, Zinc Pyrithione) goes deeper into the pores, so it doesn’t rinse out and continues to protect you against dandruff long after the shower

*clean better – the small particles help to create more lather as you wash your hair

*leave your hair and scalp healthier – the particles spread more easily across the scalp and stay there for longer, giving your scalp the protection Zinc Omadine (ZnPT, Zinc Pyrithione) needs and allowing your hair to grow from a healthier base



PROPERTIES OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
In the crystalline state, Zinc Omadine (ZnPT, Zinc Pyrithione) exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



BACTERICIDAL MECHANISM OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Omadine (ZnPT, Zinc Pyrithione) varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Omadine (ZnPT, Zinc Pyrithione) is not the same as that of many bactericides, as it kills bacteria without being consumed.



MECHANISM OF ACTION OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Zinc Omadine (ZnPT, Zinc Pyrithione)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



PREPARATION OF ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Method 1:
The principle of preparation is that ZnSO4•7H2O reacts with SPT to produce Zinc Omadine (ZnPT, Zinc Pyrithione) and sodium sulfate.
Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.

The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain Zinc Omadine (ZnPT, Zinc Pyrithione) crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Omadine (ZnPT, Zinc Pyrithione) powder.

Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.

Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.

Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Omadine (ZnPT, Zinc Pyrithione) with a yield of about 75%.



SHAMPOO ZINC OMADINE (ZnPT, ZINC PYRITHIONE) MARKET: OVERVIEW
The demand for Zinc Omadine (ZnPT, Zinc Pyrithione) from the intended end use industries is anticipated to drive market expansion.
One of the main factors influencing Zinc Omadine (ZnPT, Zinc Pyrithione)'s growth is the usage of antibacterial coating in numerous applications, including the food and beverage, textile, and paint and coating sectors for anti-bacterial activity.
A further important element that has been thought to propel the growth of the worldwide Zinc Omadine (ZnPT, Zinc Pyrithione) market is the expansion and increased demand for personal care products.



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811

Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble

Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature:
No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C

Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate



FIRST AID MEASURES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC OMADINE (ZnPT, ZINC PYRITHIONE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC OMADINE (ZOE)
Zinc Omadine (ZOE) is a white to slight yellow powder
Zinc Omadine (ZOE) is a coordination complex of zinc.
Zinc Omadine (ZOE) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn



SYNONYMS:
Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT, Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc,bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-,(T-4)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-,(T-4)-, 2(1H)-Pyridinethione,1-hydroxy-,zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc, Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc,bis(2-pyridinylthio)-,N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione,zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, 1192-70-7, 1320-68-9, 3138-01-0, 3590-23-6, 3865-77-8, 14376-32-0, 15686-64-3, 16782-00-6, 17652-47-0, 31089-48-2, 35430-20-7, 39412-61-8, 51148-10-8, 51406-57-6, 55172-61-7, 74261-71-5, 109702-19-4, 118480-78-7, 162400-43-3, 186322-74-7, 192458-89-2, 208398-70-3, 226883-65-4, 244778-79-8, 266692-38-0, 318995-78-7, 943428-71-5, 1021487-49-9, 1199553-62-2, 1323439-04-8, 2173031-33-7, 2218447-38-0, Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-, (T-4)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc, Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc, bis(2-pyridinylthio)-, N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione, zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, Zinc bis(2-mercaptopyridine-N-oxide), Zinc Omacide ZOE, FK-C, RUCO-BAC ZPY, Microcare ZP, Neostuf ZP 10, Zinc, bis[(2-pyridinethiol-κS2) 1-oxidato]-, Bis[(2-pyridinethiol-κS2) 1-oxidato]zinc, 2-Pyridinethiol, 1-oxide, zinc salt (2:1), Biomaster 627, ZPT 38, Zinc Omadine FPS, Kopthione, 1-HYDROXY-2-PYRIDINE THIONE, ZN SALT, 1-HYDROXYPYRIDINE-2-THIONE ZINC, 1-HYDROXYPYRIDINE-2-THIONE ZINC SALT, 2-mercaptopyridine-1-oxide zinc salt, 2-MERCAPTOPYRIDINE N-OXIDE ZINC, 2-MERCAPTOPYRIDINE N-OXIDE ZINC SALT, 2-PYRIDINETHIOL 1-OXIDE ZINC SALT, BIS(1-HYDROXY-2(H)-PYRIDINETHIONATO)ZINC, BIS(2-PYRIDYLTHIO) ZINC 1,1'-DIOXIDE, de-squaman, MERCAPTOPYRIDINE N-OXIDE ZINC SALT, N-HYDROXYPYRIDINETHIONE ZINC SALT, OM-1563, omadine zinc, PYRITHIONE, Pyrithione zinc, PYRITHIONE ZINC SALT, SALTPYRITHIONE ZINC, vancide zp, Zinc 1-hydroxypyridine-2-thione



Zinc Omadine (ZOE) is a fungistatic and baceriostatic compound that has a variety of uses.
Zinc Omadine (ZOE) is the most important antidandruf agent in the world, which used for more than 30 years in shampoo.
Zinc Omadine (ZOE) shows excellent inhibiting effect on pytyrosporum ovale that causes dandruff.


Zinc Omadine (ZOE) is a zinc complex of pyrithione.
Zinc Omadine (ZOE) possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc Omadine (ZOE) offers antimicrobial protection in the wet and in the dry film state.


Zinc Omadine (ZOE) is a higher viscosity, fine particle dispersion specifically formulated so as to not discolour due to interactions with various elements that can be present in some paint formulations.
Zinc Omadine (ZOE) is a highly effective broad spectrum biocide for the preservation of industrial products against spoilage from yeasts/moulds (fungi), algae and bacteria.


Zinc Omadine (ZOE) is an aqueous dispersion specifically formulated to be colour-stable in the presence of various elements that may be present in some paint formulations and that interact with the active ingredient.
Soluble iron, in particular, can react with the Zinc Omadine (ZOE), producing a grey-blue discolouration in the paint.


By using Zinc Omadine (ZOE), this interaction with iron is avoided.
Zinc Omadine (ZOE) is the latest addition to our Omadine product line.
Zinc Omadine (ZOE) is a higher viscosity, fine particle dispersion specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


In particular, soluble iron can react with the Zinc Omadine (ZOE) active ingredient and a grayblue color may develop.
By using Zinc Omadine (ZOE) in these formulations, reaction of iron with the zinc pyrithione component is eliminated.
Zinc Omadine (ZOE) is registered with the United States Environmental Protection Agency


Zinc Omadine (ZOE) is a highly active, broad-spectrum antimicrobial biocide, which is a 48% aqueous dispersion of zinc pyrithione.
Zinc Omadine (ZOE) is a white to slight yellow powder
Zinc Omadine (ZOE) is a coordination complex of zinc.


The boiling point of Zinc Omadine (ZOE) is 253.8°C, and Flash point is 107.3°C.
Zinc Omadine (ZOE) is insoluble in water.
Zinc Omadine (ZOE) is renowned for its microbial growth control properties.


Zinc Omadine (ZOE) has a boiling point of 253.8 u00b0C at 760 mmHg.
Zinc Omadine (ZOE) showcases a stable melting point at 262u00b0C
The flash point of Zinc Omadine (ZOE) is calculated at 107.3 u00b0C.


Density 1.782 g/cm3 at 25 u00b0C is the noted density of Zinc Omadine (ZOE).
Zinc Omadine (ZOE)'s solubility is less than 0.1g per 100 mL at 21u00b0C.
Apart from its properties, Zinc Omadine (ZOE) also calls for particular storage considerations.


Zinc Omadine (ZOE) must be kept in tightly sealed containers or cylinders, stored in cool, dry, and dark locations, away from ignition sources and any incompatible materials.
Zinc Omadine (ZOE) is necessary to label the storage area correctly and protect the containers from any physical damage.


Zinc Omadine (ZOE) finds its significance in various endeavors, primarily in the creation of antimicrobial coatings and additives, as well as other medical applications.
Its robust characteristics and versatility make Zinc Omadine (ZOE) a valuable addition to the B2B marketplace.


Zinc Omadine (ZOE) is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Zinc Omadine (ZOE) is considered as a coordination complex of zinc.
The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers.


In the crystalline state, Zinc Omadine (ZOE) exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociat
Zinc Omadine (ZOE) is a fine beige granules.


It is a naturally round sand with a Zinc Omadine (ZOE) infused vinyl coating that is effective against bacteria, mold, mildew and algae all while being long-lasting and durable.
Zinc Omadine (ZOE) is non-absorbant and will minimize the associated odors caused by pet urine.



USES and APPLICATIONS of ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.
Zinc Omadine (ZOE) is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Omadine (ZOE) is also often used in kitchen sponges as an antibacterial treatment.
Zinc Omadine (ZOE) has broad spectrum bactericide and marine antifouling material, and is well used for cosmetic, shampoo, skins medicine, adhesive and coating painting and so on.


Zinc Omadine (ZOE) is used created specifically for film protection of coatings.
Zinc Omadine (ZOE) provides superior dry antifungal protection for Lethex paints compared to carbendazim based products.
The active ingredient in Zinc Omadine (ZOE) is also one of the most effective dry algaecides known in the industry.


Along with all types of Zinc Omadine (ZOE) can be used in all types of latex building coatings, both for external and internal applications.
Zinc Omadine (ZOE) is particularly effective as a single active dry film preservative for.
Zinc Omadine (ZOE) is a higher viscosity, fine particle dispersion in water of zinc pyrithione specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


Zinc Omadine (ZOE) is used to inhibit the growth of fungi, both yeasts and molds, the growth of algae, and the growth of a broad spectrum of both Gram positive and Gram negative bacteria.
Zinc Omadine (ZOE) is used in both personal care and industrial product applications.


Zinc Omadine (ZOE) is also used in water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc Omadine (ZOE) is used architectural and industrial paint and coatings
Zinc Omadine (ZOE) is used construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds


Zinc Omadine (ZOE) is used building materials including ceilings, ceiling tiles, walls andinternal partitions
Zinc Omadine (ZOE) is a superordinary anti-scale agent and anti-lipid overflow agent.
Zinc Omadine (ZOE) can effectively eliminate eumycete which produces dandruff, and result in relieving itching, removing dandruff, diminishing phalacrosis and deferring poliosis.


Therefore, Zinc Omadine (ZOE) is considered as a highly effective and safe product.
Zinc Omadine (ZOE) will add the value of shampoo and meet the high demands from consumers.
For this reason, Zinc Omadine (ZOE) is widely used in the production of shampoo.


Moreover, as a fine,broad-spectrum,environment-friendly and low toxic antiseptics, Zinc Omadine (ZOE) can be used in civil coating, adhesive and carpet.
The mixture of Zinc Omadine (ZOE) and Cu2O also can be used as marine antifouling coating to prevent adhering of shells, seaweeds and aquatic organisms to hulls.


Zinc Omadine (ZOE) and its relative products enjoy tremendous potential and broad space in pesticide field with properties of high-efficiency, environmental protection,hypotoxicity and broad-spectrum.
Zinc Omadine (ZOE) is used as anti-dandruff agent and bactericide.


Zinc Omadine (ZOE) is used in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.
Zinc Omadine (ZOE) is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Zinc Omadine (ZOE) has fungistatic (that is,it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.


Zinc Omadine (ZOE) can be used to infill artificial lawns and playgrounds.
Zinc Omadine (ZOE) keeps turf looking new and natural.
Zinc Omadine (ZOE) is well graded to ensure excellent drainage.


Zinc Omadine (ZOE) can be used to protect the surfaces of coatings and other dry films from fungal and algal growth.
In addition, Zinc Omadine (ZOE) can provide good activity against both fungi and algae, offer long-term protection due to its low water solubility, and does not trigger environmental symbol labeling at normal use levels.


Zinc Omadine (ZOE) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Omadine (ZOE) is a useful building block for chemical synthesis.


Zinc Omadine (ZOE) is extremely effective in eliminating the fungi, Malassezia spp., which is directly linked to the scalp condition, dandruff.
An important characteristic of Zinc Omadine (ZOE) is that it is efficacious against numerous other organisms beyond Malassezia, including the various bacteria species associated with producing odor on the skin.


Shampoo for dandruff, Zinc Omadine (ZOE) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging ,control white hair and hair loss generation.
Zinc Omadine (ZOE) is also used as a cosmetic preservative, oil, paint biocide.


Zinc Omadine (ZOE) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Omadine (ZOE) is a coordination complex of zinc and pyrithione that has antimicrobial, anticancer, and fungicidal activities.
Zinc Omadine (ZOE) is active against the bacteria E. coli, S. aureus, K. pneumoniae, A. baumannii, P. aeruginosa, E. faecium, E. faecalis, and E. cloacae (MICs = 1-4 µg/ml) and the fungus P. ovale when used at concentrations ranging from 0.01 to 10 µg/ml.


Zinc Omadine (ZOE) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg/kg per week for six weeks.
Topical application of Zinc Omadine (ZOE) completely prevents Aspergillus growth in soy meal-derived adhesives.
Formulations containing Zinc Omadine (ZOE) have been used in the treatment of dandruff and in the prevention of fungal growth in industrial applications.



GENERAL PROPERTIES OF ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) exhibits pronounced growth inhibiting activity against abroad
spectrum of both Gram negative and Gram positive bacteria
Zinc Omadine (ZOE) inhibits the growth of fungi, both yeast and mold
Zinc Omadine (ZOE) is insoluble in water



WHAT DOES ZINC OMADINE (ZOE) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



ALTERNATIVES OF ZINC OMADINE (ZOE):
*KETOCONAZOLE,
*SELENIUM SULFIDE



PROPERTIES OF ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) is a white to slight yellow powder or white suspension
Zinc Omadine (ZOE) is in water Insoluble (Stability SZinc Omadine (ZOE) is s



DISPERSION OF ZINC OMADINE (ZOE):
*is a color stable, fine particle dispersion (in water) of zinc pyrithione
inhibits the growth of fungi, both yeasts and molds.
*inhibits the growth of algae.
*inhibits the growth of a broad spectrum of both Gram positive and Gram negative bacteria.



KEY FEATURES OF ZINC OMADINE (ZOE):
Zinc Omadine (ZOE) is off-white to tan color.
Molecular Weight of Zinc Omadine (ZOE) is 317.69
Zinc Omadine (ZOE) is used found in personal care products like soaps, shampoos, and industrial items such as paints, coatings

Zinc Omadine (ZOE) is a celebrated compound in the chemical industry, celebrated for its unique microbiocidal properties and versatile applications.
Zinc Omadine (ZOE) consists of a pale off-white to tan powder, suitable for various industry applications.
The low solubility of Zinc Omadine (ZOE), along with its impressive stability, makes it an ideal choice for unique solutions in various sectors.



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE (ZOE):
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3

Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811

Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble

Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature:
No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C

Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate



FIRST AID MEASURES of ZINC OMADINE (ZOE):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE (ZOE):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE (ZOE):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE (ZOE):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE (ZOE):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC OMADINE (ZOE):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC OMADINE ZOE ANTIMICROBIAL
Zinc Omadine ZOE Antimicrobial is a zinc complex of pyrithione.
Zinc Omadine ZOE Antimicrobial is a white to slight yellow powder.
Zinc Omadine ZOE Antimicrobial is a coordination complex of zinc.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn



SYNONYMS:
Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc, bis(2-pyridinylthio)-, N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione, zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, Zinc bis(2-mercaptopyridine-N-oxide), Zinc Omacide ZOE, FK-C, RUCO-BAC ZPY, Microcare ZP, Neostuf ZP 10, Zinc, bis[(2-pyridinethiol-κS2) 1-oxidato]-, Bis[(2-pyridinethiol-κS2) 1-oxidato]zinc, 2-Pyridinethiol, 1-oxide, zinc salt (2:1), Biomaster 627, ZPT 38, Zinc Omadine FPS, Kopthione, 1-HYDROXY-2-PYRIDINE THIONE, ZN SALT, 1-HYDROXYPYRIDINE-2-THIONE ZINC, 1-HYDROXYPYRIDINE-2-THIONE ZINC SALT, 2-mercaptopyridine-1-oxide zinc salt, 2-MERCAPTOPYRIDINE N-OXIDE ZINC, 2-MERCAPTOPYRIDINE N-OXIDE ZINC SALT, 2-PYRIDINETHIOL 1-OXIDE ZINC SALT, BIS(1-HYDROXY-2(H)-PYRIDINETHIONATO)ZINC, BIS(2-PYRIDYLTHIO) ZINC 1,1'-DIOXIDE, de-squaman, MERCAPTOPYRIDINE N-OXIDE ZINC SALT, N-HYDROXYPYRIDINETHIONE ZINC SALT, OM-1563, omadine zinc, PYRITHIONE, Pyrithione zinc, PYRITHIONE ZINC SALT, SALTPYRITHIONE ZINC, vancide zp, Zinc 1-hydroxypyridine-2-thione, Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT, Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc,bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-,(T-4)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc,bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-,(T-4)-, 2(1H)-Pyridinethione,1-hydroxy-,zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc, Zinc pyrithione, Omadine Zinc, Pyrithione zinc, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, Zinc,bis(2-pyridinylthio)-,N,N′-dioxide, Zinc 2-pyridinethiol 1-oxide, Vancide P, Zinc Omadine, ZPT, OM 1563, 2-Mercaptopyridine 1-oxide zinc salt, Zinc 1-hydroxy-2-pyridinethione, 2-Pyridinethiol 1-oxide zinc salt, Zinc pyrethion, 2-Pyridinethiol N-oxide zinc salt, Zincpolyanemine, Zinc 2-mercaptopyridine N-oxide, Zinc pyridine-2-thione-N-oxide, FSB 8332, 1-Hydroxy-2-pyridinethione,zinc salt, Evafine P 50, Tomicide Z 50, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Hokucide ZPT, Finecide ZPT, Biocut ZP, Bis(2-pyridinethiol 1-oxide)zinc, BC-J, Tomicide ZPT 50, Niccanon SKT, Niccanon ZP, Marukacide YP-DP, Zinc bis(2-pyridylthio-1-oxide), Sebulon Shampoo, Desquaman, Danex, ZNP Bar, Tomicide ZPT, NSC 290409, AF-Z, Tomicide ZPT 100, Zinc Pyrion, 2-Pyridylthiol-1-oxide zinc salt, Microban Additive ZO 1, ZO-E, Zn Omadine ZOE, Microban Z 01, Sanitized TH 22-27, Clean-Bio ZP, Sanaizol 200, Dantrol, Zincopan, Sanitized TH 27-24BT, Slaoff 95, Slaoff 94, Vedexil-PZ, Hybricide 89, Denistat ANK, ZOE-T, Intercide ZNP, SR-A 103, ZnPT, Zinc Omadine ZOE Dispersion, Zinc Omadine ZOE, TH 22-27, 1192-70-7, 1320-68-9, 3138-01-0, 3590-23-6, 3865-77-8, 14376-32-0, 15686-64-3, 16782-00-6, 17652-47-0, 31089-48-2, 35430-20-7, 39412-61-8, 51148-10-8, 51406-57-6, 55172-61-7, 74261-71-5, 109702-19-4, 118480-78-7, 162400-43-3, 186322-74-7, 192458-89-2, 208398-70-3, 226883-65-4, 244778-79-8, 266692-38-0, 318995-78-7, 943428-71-5, 1021487-49-9, 1199553-62-2, 1323439-04-8, 2173031-33-7, 2218447-38-0, Zinc, bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]-, (T-4)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-, (T-4)-, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, (T-4)-Bis[1-(hydroxy-κO)-2(1H)-pyridinethionato-κS2]zinc,



Zinc Omadine ZOE Antimicrobial is a naturally round sand that is effective against bacteria, mold, mildew and algae all while being long-lasting and durable.
Zinc Omadine ZOE Antimicrobial is non-absorbant and will minimize the associated odors caused by pet urine.
Zinc Omadine ZOE Antimicrobial is a highly active, broad-spectrum zinc complex of pyrithione.


Zinc Omadine ZOE Antimicrobial is a white to slight yellow powder.
Zinc Omadine ZOE Antimicrobial is a coordination complex of zinc.
Zinc Omadine ZOE Antimicrobial is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.


Zinc Omadine ZOE Antimicrobial is a zinc complex of pyrithione.
Zinc Omadine ZOE Antimicrobial is an aqueous dispersion specifically formulated to be colour-stable in the presence of various elements that may be present in some paint formulations and that interact with the active ingredient.


Soluble iron, in particular, can react with the Zinc Omadine ZOE Antimicrobial, producing a grey-blue discolouration in the paint.
Zinc Omadine ZOE Antimicrobial possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc Omadine ZOE Antimicrobial is a zinc complex of pyrithione.


Zinc Omadine ZOE Antimicrobial possesses high activity and broad-spectrum antimicrobial properties (against bacteria, fungi, and algaecide).
Zinc Omadine ZOE Antimicrobial offers antimicrobial protection in the wet and in the dry film state.
Zinc Omadine ZOE Antimicrobial is a fungistatic and baceriostatic compound that has a variety of uses.


Zinc Omadine ZOE Antimicrobial has a boiling point of 253.8 u00b0C at 760 mmHg.
Zinc Omadine ZOE Antimicrobial showcases a stable melting point at 262u00b0C
The flash point of Zinc Omadine ZOE Antimicrobial is calculated at 107.3 u00b0C.


Density 1.782 g/cm3 at 25 u00b0C is the noted density of Zinc Omadine ZOE Antimicrobial.
Zinc Omadine ZOE Antimicrobial's solubility is less than 0.1g per 100 mL at 21u00b0C.
Apart from its properties, Zinc Omadine ZOE Antimicrobial also calls for particular storage considerations.


Zinc Omadine ZOE Antimicrobial is the most important antidandruf agent in the world, which used for more than 30 years in shampoo.
Zinc Omadine ZOE Antimicrobial shows excellent inhibiting effect on pytyrosporum ovale that causes dandruff.
Zinc Omadine ZOE Antimicrobial offers antimicrobial protection in the wet and in the dry film state.


Zinc Omadine ZOE Antimicrobial is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump.
Zinc Omadine ZOE Antimicrobial is considered as a coordination complex of zinc.
The pyrithione ligands, which are formally monoanions, are chelated to Zn 2+ via oxygen and sulfur centers.


The boiling point of Zinc Omadine ZOE Antimicrobial is 253.8°C, and Flash point is 107.3°C.
Zinc Omadine ZOE Antimicrobial is insoluble in water.
Zinc Omadine ZOE Antimicrobial is renowned for its microbial growth control properties.



USES and APPLICATIONS of ZINC OMADINE ZOE ANTIMICROBIAL:
Zinc Omadine ZOE Antimicrobial is used in both personal care and industrial product applications.
The recommended applications of Zinc Omadine ZOE Antimicrobial are water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc Omadine ZOE Antimicrobial is a dry film and in-can preservative for water-based paints.


Zinc Omadine ZOE Antimicrobial is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.
Zinc Omadine ZOE Antimicrobial is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Omadine ZOE Antimicrobial is also used as a dry film preservative for marine anti-fouling paints.
Zinc Omadine ZOE Antimicrobial is a highly active, broad-spectrum zinc complex of pyrithione.
Zinc Omadine ZOE Antimicrobial is also often used in kitchen sponges as an antibacterial treatment.


Zinc Omadine ZOE Antimicrobial has broad spectrum bactericide and marine antifouling material, and is well used for cosmetic, shampoo, skins medicine, adhesive and coating painting and so on.
Zinc Omadine ZOE Antimicrobial is used created specifically for film protection of coatings.


Zinc Omadine ZOE Antimicrobial provides superior dry antifungal protection for Lethex paints compared to carbendazim based products.
The active ingredient in Zinc Omadine ZOE Antimicrobial is also one of the most effective dry algaecides known in the industry.
Zinc Omadine ZOE Antimicrobial is used building materials including ceilings, ceiling tiles, walls andinternal partitions


Zinc Omadine ZOE Antimicrobial is a superordinary anti-scale agent and anti-lipid overflow agent.
Zinc Omadine ZOE Antimicrobial can effectively eliminate eumycete which produces dandruff, and result in relieving itching, removing dandruff, diminishing phalacrosis and deferring poliosis.


Zinc Omadine ZOE Antimicrobial offers very good protection against microbial growth including bacteria, fungi and algae.
Along with all types of Zinc Omadine ZOE Antimicrobial can be used in all types of latex building coatings, both for external and internal applications.
Zinc Omadine ZOE Antimicrobial is particularly effective as a single active dry film preservative for.


Zinc Omadine ZOE Antimicrobial is a higher viscosity, fine particle dispersion in water of zinc pyrithione specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.
Zinc Omadine ZOE Antimicrobial is used to inhibit the growth of fungi, both yeasts and molds, the growth of algae, and the growth of a broad spectrum of both Gram positive and Gram negative bacteria.


Zinc Omadine ZOE Antimicrobial is used in both personal care and industrial product applications.
Zinc Omadine ZOE Antimicrobial is also used in water-based caulks, adhesives, sealants, gaskets, SBR and thermoplastic resins.
Zinc Omadine ZOE Antimicrobial is used architectural and industrial paint and coatings


Zinc Omadine ZOE Antimicrobial is used construction materials including flooring adhesives, caulks, sealants, grouts and jointing compounds
Zinc Omadine ZOE Antimicrobial is a higher viscosity, fine particle dispersion specifically formulated so as to not discolor due to interactions with various elements that can be present in some paint formulations.


Zinc Omadine ZOE Antimicrobial and its relative products enjoy tremendous potential and broad space in pesticide field with properties of high-efficiency, environmental protection,hypotoxicity and broad-spectrum.
Zinc Omadine ZOE Antimicrobial is used as anti-dandruff agent and bactericide.


Zinc Omadine ZOE Antimicrobial helps prevent growth of bacteria, mold and mildew.
Therefore, Zinc Omadine ZOE Antimicrobial is considered as a highly effective and safe product.
Zinc Omadine ZOE Antimicrobial will add the value of shampoo and meet the high demands from consumers.


For this reason, Zinc Omadine ZOE Antimicrobial is widely used in the production of shampoo.
Moreover, as a fine,broad-spectrum,environment-friendly and low toxic antiseptics, Zinc Omadine ZOE Antimicrobial can be used in civil coating, adhesive and carpet.


The mixture of Zinc Omadine ZOE Antimicrobial and Cu2O also can be used as marine antifouling coating to prevent adhering of shells, seaweeds and aquatic organisms to hulls.
Zinc Omadine ZOE Antimicrobial can be used to infill artificial lawns, putting greens, and playgrounds.


Zinc Omadine ZOE Antimicrobial keeps turf looking new and natural.
Zinc Omadine ZOE Antimicrobial is well graded to ensure excellent drainage.
Zinc Omadine ZOE Antimicrobial is used in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.


Zinc Omadine ZOE Antimicrobial is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Zinc Omadine ZOE Antimicrobial has fungistatic (that is,it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.


Zinc Omadine ZOE Antimicrobial can be used to infill artificial lawns and playgrounds.
Zinc Omadine ZOE Antimicrobial keeps turf looking new and natural.
Zinc Omadine ZOE Antimicrobial is well graded to ensure excellent drainage.



GENERAL PROPERTIES OF ZINC OMADINE ZOE ANTIMICROBIAL:
Zinc Omadine ZOE Antimicrobial exhibits pronounced growth inhibiting activity against abroad
spectrum of both Gram negative and Gram positive bacteria
Zinc Omadine ZOE Antimicrobial inhibits the growth of fungi, both yeast and mold
Zinc Omadine ZOE Antimicrobial is insoluble in water



WHAT DOES ZINC OMADINE ZOE ANTIMICROBIAL DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



ALTERNATIVES OF ZINC OMADINE ZOE ANTIMICROBIAL:
*KETOCONAZOLE
*SELENIUM SULFIDE



PROPERTIES OF ZINC OMADINE ZOE ANTIMICROBIAL:
*Non-toxic
*Effective Product
*Superior Quality
*UV Resistant
*Pet Friendly.



PHYSICAL and CHEMICAL PROPERTIES of ZINC OMADINE ZOE ANTIMICROBIAL:
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature:
No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C

Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder

Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17

Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%

Particle size :D70Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811

DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry,
dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic

Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C

PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point:
Melting point/range: 267 °C



FIRST AID MEASURES of ZINC OMADINE ZOE ANTIMICROBIAL:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC OMADINE ZOE ANTIMICROBIAL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC OMADINE ZOE ANTIMICROBIAL:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC OMADINE ZOE ANTIMICROBIAL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC OMADINE ZOE ANTIMICROBIAL:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC OMADINE ZOE ANTIMICROBIAL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC OXIDE
DESCRIPTION:

Zinc oxide is a largely inert, white compound which is used very widely as a bulking agent or filler, and as a white pigment.
Zinc oxide is found in some rubber, glass and ceramic products, and finds use in the chemical industry as a catalyst.
Zinc oxide is also used in paints as a corrosion inhibitor and for mildew control.


CAS Number, 1314-13-2
EC Number, 215-222-5


SYNONYMS OF ZINC OXIDE:
Zinc white, calamine, philosopher's wool, Chinese white, flowers of zinc,ZINC OXIDE,1314-13-2,oxozinc,Zinc White,Zinc Oxide Powder,Chinese White,Snow white,Akro-zinc bar 85,MFCD00011300,Azo-33,Supertah,Zincite,Azodox,Lassars Paste,Flores de zinci,Lassar Paste,Zinci Oxicum,Hubbuck's White,Blanc de Zinc,Vandem VPC,White seal-7,K-Zinc,174846-84-5,Akro-zinc bar 90,Azodox-55,Azodox-55TT,Red Seal 9,Electrox 2500,Kadox 15,Zinc oxide [USAN],Protox 166,Protox 168,Protox 169,Caswell No. 920,Electox 2500,Cynku tlenek [Polish],Desitin,Nogenol,C-Weiss 8 [German],zincum oxidatum,Azo-55TT,Azo-66TT,Azo-77TT,Zinc gelatin,RVPaque,Azo 22,Azo-55,Azo-66,Azo-77,No-Genol,Zinc oxide substrate, 10x10x0.5mm, polished one side, 0001 orientation,Zinc oxide, 99.99% trace metals basis,CCRIS 1309,C-Weiss 8,HSDB 5024,A&D Medicated Ointment,EINECS 215-222-5,UNII-SOI2LOH54Z,Zinc oxide [USP:JAN],EPA Pesticide Chemical Code 088502,Leaded zinc oxide,ZN-0401 E 3/16'',ZnO Quantum Dots,Zinc Oxide Slurry,Zinc oxide, heavy,Zinc oxide (TN),Zinc Oxide Nanowire,Zinc Oxide Nanowires,Zine Oxide ,(S),Zinc Oxide Dispersion,Zinc Oxide Nanopowder,Zinc oxide, Nanotek?,Zinc oxide, Puratronic,Zinc Oxide Quantum Dots,Zinc oxide,99.99%,EC 215-222-5,Zinc oxide (JP17/USP),Zinc oxide, sintered tablets,Zinc oxide, LR, >=99%,Aluminium Doped ZnO Dispersion,Zinc oxide [USAN:USP:JAN],Zinc oxide, analytical standard,Zinc Oxide Nanopowder Dispersion,Zinc Oxide Nanopowder (Type I),Zinc oxide, NanoArc ZN-0605,Zinc oxide, p.a., 99.0%,XLOMVQKBTHCTTD-UHFFFAOYSA-N,Zinc Oxide Nanopowder (Type II),Zinc Oxide Dispersion Wood Coating,Zinc Oxide Powder, 99.9% Nano,Yttrium Doped Zinc Oxide Dispersion,Europium Doped Zinc Oxide Dispersion,Zinc oxide, USP, 99-100.5%,AKOS015904168,DB09321,Zinc oxide, ACS reagent, >=99.0%,Zinc oxide, 30nm,20 wt.% isopropanol,Zinc oxide, tested according to Ph.Eur.,8051-03-4,Zinc oxide, 99.999% trace metals basis,Zinc oxide, SAJ first grade, >=99.0%,Zinc oxide, JIS special grade, >=99.0%,CS-0179846,FT-0631786,FT-0640838,FT-0645092,Antimony Tin Dioxide (ATO) Sputtering Targets,D01170,Zinc oxide, nanopowder, =99.0% (KT),AZO Powder / AZO MicroPowder / ZnO Doped with Metal Aluminum,Zinc oxide, nanopowder, 97%,Zinc oxide, ReagentPlus(R), powder, 99% Nano,Zinc oxide sputtering target, 50.8mm (2.0in) dia x 3.18mm (0.125in) thick,Zinc oxide sputtering target, 50.8mm (2.0in) dia x 6.35mm (0.250in) thick,Zinc oxide, NanoTek Z1102PMA, 50% in 1,2-propanediol monomethyl ether acetate, colloidal dispersion,Zinc oxide, sputtering target, diam. x thickness 3.00 in. x 0.125 in., 99.99% trace metals basis



Zinc is an essential trace element, and zinc oxide is added to fertilizers, animal feed, and vitamin supplements.
Zinc oxide is also used in a many cosmetic and medical products and in toiletries, as it has antibacterial and deodorant properties.
Zinc oxide is found in, for example, baby powder and anti-dandruff shampoos, in calamine lotion and in sticking plasters and dental cement.

Its strong absorption of ultra-violet (UV) light has led to its use in sunscreen lotions.
Zinc oxide blocks both UVA (longer wavelength) and UVB (shorter wavelength) radiation, protecting against sunburn, skin damage and cancer.


Zinc oxide is an inorganic compound with the formula ZnO.
Zinc oxide is a white powder that is insoluble in water.

Zinc oxide is used as an additive in numerous materials and products including cosmetics, food supplements, rubbers, plastics, ceramics, glass, cement, lubricants, paints, sunscreens, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, semi conductors, and first-aid tapes.
Although Zinc oxide occurs naturally as the mineral zincite, most zinc oxide is produced synthetically.



Crude zinc oxide is a yellow-gray granular solid with no odor.
Zinc oxide is insoluble in water.
The primary hazard is the threat posed to the environment. Immediate steps should be taken to limit its spread to the environment.
Prolonged inhalation of the dust may result in metal fume fever with symptoms of chills, fever, muscular pain, nausea and vomiting.




Zinc oxide is an inorganic compound used in a number of manufacturing processes.
Zinc oxide can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes.

Zinc oxide occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically.
Zinc oxide is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.






HISTORY OF ZINC OXIDE:
Zinc compounds were probably used by early humans, in processed and unprocessed forms, as a paint or medicinal ointment, but their composition is uncertain.
The use of pushpanjan, probably zinc oxide, as a salve for eyes and open wounds, is mentioned in the Indian medical text the Charaka Samhita, thought to date from 500 BC or before.
Zinc oxide ointment is also mentioned by the Greek physician Dioscorides (1st century AD)

Galen suggested treating ulcerating cancers with zinc oxide, as did Avicenna in his The Canon of Medicine.
Zinc oxide is used as an ingredient in products such as baby powder and creams against diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.

The Romans produced considerable quantities of brass (an alloy of zinc and copper) as early as 200 BC by a cementation process where copper was reacted with zinc oxide.
The zinc oxide is thought to have been produced by heating zinc ore in a shaft furnace.
This liberated metallic zinc as a vapor, which then ascended the flue and condensed as the oxide.

This process was described by Dioscorides in the 1st century AD.
Zinc oxide has also been recovered from zinc mines at Zawar in India, dating from the second half of the first millennium BC.

From the 12th to the 16th century zinc and zinc oxide were recognized and produced in India using a primitive form of the direct synthesis process.
From India, zinc manufacture moved to China in the 17th century. In 1743, the first European zinc smelter was established in Bristol, United Kingdom.

Around 1782 Louis-Bernard Guyton de Morveau proposed replacing lead white pigment with zinc oxide.
The main usage of zinc oxide (zinc white) was in paints and as an additive to ointments.

Zinc white was accepted as a pigment in oil paintings by 1834 but it did not mix well with oil.
This problem was solved by optimizing the synthesis of ZnO.

In 1845, Edme-Jean Leclaire in Paris was producing the oil paint on a large scale, and by 1850, zinc white was being manufactured throughout Europe.
The success of zinc white paint was due to its advantages over the traditional white lead: zinc white is essentially permanent in sunlight, it is not blackened by sulfur-bearing air, it is non-toxic and more economical.

Because zinc white is so "clean" it is valuable for making tints with other colors, but it makes a rather brittle dry film when unmixed with other colors.
For example, during the late 1890s and early 1900s, some artists used zinc white as a ground for their oil paintings.
All those paintings developed cracks over the years.


In recent times, most zinc oxide was used in the rubber industry to resist corrosion.
In the 1970s, the second largest application of ZnO was photocopying.
High-quality ZnO produced by the "French process" was added to photocopying paper as a filler.
This application was soon displaced by titanium


USES OF ZINC OXIDE (ZNO):
Zinc oxide is used as a bulking agent.
Zinc oxide is used as a colourant.
Zinc oxide is used in over-the-counter drug products.

Zinc oxide is used as a skin protectant.
Zinc oxide is used as a sunscreen as it reduces and prevents sunburn.
Zinc oxide is used in preventing premature skin ageing.

Zinc oxide is Used in nail products.
Zinc oxide is used as a diaper rash ointment.



CHEMICAL PROPERTIES OF ZINC OXIDE:
Pure ZnO is a white powder, but in nature it occurs as the rare mineral zincite, which usually contains manganese and other impurities that confer a yellow to red color.

Crystalline zinc oxide is thermochromic, changing from white to yellow when heated in air and reverting to white on cooling.
This color change is caused by a small loss of oxygen to the environment at high temperatures to form the non-stoichiometric Zn1+xO, where at 800 °C, x = 0.00007.


Zinc oxide is an amphoteric oxide.
Zinc oxide is nearly insoluble in water, but it will dissolve in most acids, such as hydrochloric acid:
ZnO + 2 HCl → ZnCl2 + H2O
Solid zinc oxide will also dissolve in alkalis to give soluble zincates:
ZnO + 2 NaOH + H2O → Na2[Zn(OH)4]


ZnO reacts slowly with fatty acids in oils to produce the corresponding carboxylates, such as oleate or stearate.
When mixed with a strong aqueous solution of zinc chloride, ZnO forms cement-like products best described as zinc hydroxy chlorides.
This cement was used in dentistry.


ZnO also forms cement-like material when treated with phosphoric acid; related materials are used in dentistry.
A major component of zinc phosphate cement produced by this reaction is hopeite, Zn3(PO4)2•4H2O.

ZnO decomposes into zinc vapor and oxygen at around 1975 °C with a standard oxygen pressure.
In a carbothermic reaction, heating with carbon converts the oxide into zinc vapor at a much lower temperature (around 950 °C).
ZnO + C → Zn(Vapor) + CO



PHYSICAL PROPERTIES OF ZINC OXIDE:
Structure:
Zinc oxide crystallizes in two main forms, hexagonal wurtzite and cubic zincblende.
The wurtzite structure is most stable at ambient conditions and thus most common.
The zincblende form can be stabilized by growing ZnO on substrates with cubic lattice structure.


In both cases, the zinc and oxide centers are tetrahedral, the most characteristic geometry for Zn(II).
ZnO converts to the rocksalt motif at relatively high pressures about 10 GPa.
Hexagonal and zincblende polymorphs have no inversion symmetry (reflection of a crystal relative to any given point does not transform it into itself).

This and other lattice symmetry properties result in piezoelectricity of the hexagonal and zincblende ZnO, and pyroelectricity of hexagonal ZnO.
The hexagonal structure has a point group 6 mm (Hermann–Mauguin notation) or C6v (Schoenflies notation), and the space group is P63mc or C6v4.
The lattice constants are a = 3.25 Å and c = 5.2 Å; their ratio c/a ~ 1.60 is close to the ideal value for hexagonal cell c/a = 1.633.

As in most group II-VI materials, the bonding in ZnO is largely ionic (Zn2+O2−) with the corresponding radii of 0.074 nm for Zn2+ and 0.140 nm for O2−.
This property accounts for the preferential formation of wurtzite rather than zinc blende structure, as well as the strong piezoelectricity of ZnO.
Because of the polar Zn−O bonds, zinc and oxygen planes are electrically charged.

To maintain electrical neutrality, those planes reconstruct at atomic level in most relative materials, but not in ZnO – its surfaces are atomically flat, stable and exhibit no reconstruction.
However, studies using wurtzoid structures explained the origin of surface flatness and the absence of reconstruction at ZnO wurtzite surfaces in addition to the origin of charges on ZnO planes.


MECHANICAL PROPERTIES OF ZINC OXIDE:
ZnO is a wide-band gap semiconductor of the II-VI semiconductor group.
The native doping of the semiconductor due to oxygen vacancies or zinc interstitials is n-type

ZnO is a relatively soft material with approximate hardness of 4.5 on the Mohs scale.
Its elastic constants are smaller than those of relevant III-V semiconductors, such as GaN.
The high heat capacity and heat conductivity, low thermal expansion and high melting temperature of ZnO are beneficial for ceramics.

The E2 optical phonon in ZnO exhibits an unusually long lifetime of 133 ps at 10 K.
Among the tetrahedrally bonded semiconductors, it has been stated that ZnO has the highest piezoelectric tensor, or at least one comparable to that of GaN and AlN.


This property makes it a technologically important material for many piezoelectrical applications, which require a large electromechanical coupling.
Therefore, ZnO in the form of thin film has been one of the most studied resonator materials for thin-film bulk acoustic resonators.


ELECTRICAL AND OPTICAL PROPERTIES OF ZINC OXIDE:
Favourable properties of zinc oxide include good transparency, high electron mobility, wide band gap, and strong room-temperature luminescence.
Those properties make ZnO valuable for a variety of emerging applications: transparent electrodes in liquid crystal displays, energy-saving or heat-protecting windows, and electronics as thin-film transistors and light-emitting diodes.


ZnO has a relatively wide direct band gap of ~3.3 eV at room temperature.
Advantages associated with a wide band gap include higher breakdown voltages, ability to sustain large electric fields, lower electronic noise, and high-temperature and high-power operation.
The band gap of ZnO can further be tuned to ~3–4 eV by its alloying with magnesium oxide or cadmium oxide.

Due to this large band gap, there have been efforts to create visibly transparent solar cells utilising ZnO as a light absorbing layer. However, these solar cells have so far proven highly inefficient.

Most ZnO has n-type character, even in the absence of intentional doping.
Nonstoichiometry is typically the origin of n-type character, but the subject remains controversial.

An alternative explanation has been proposed, based on theoretical calculations, that unintentional substitutional hydrogen impurities are responsible.
Controllable n-type doping is easily achieved by substituting Zn with group-III elements such as Al, Ga, In or by substituting oxygen with group-VII elements chlorine or iodine.

Reliable p-type doping of ZnO remains difficult.
This problem originates from low solubility of p-type dopants and their compensation by abundant n-type impurities.
This problem is observed with GaN and ZnSe.


Measurement of p-type in "intrinsically" n-type material is complicated by the inhomogeneity of samples.
Current limitations to p-doping limit electronic and optoelectronic applications of ZnO, which usually require junctions of n-type and p-type material.
Known p-type dopants include group-I elements Li, Na, K; group-V elements N, P and As; as well as copper and silver.

However, many of these form deep acceptors and do not produce significant p-type conduction at room temperature.
Electron mobility of ZnO strongly varies with temperature and has a maximum of ~2000 cm2/(V•s) at 80 K.
Data on hole mobility are scarce with values in the range 5–30 cm2/(V•s).

ZnO discs, acting as a varistor, are the active material in most surge arresters.
Zinc oxide is noted for its strongly nonlinear optical properties, especially in bulk.
The nonlinearity of ZnO nanoparticles can be fine-tuned according to their size.


PRODUCTION OF ZINC OXIDE:
For industrial use, ZnO is produced at levels of 105 tons per year by three main processes:

Indirect process:
In the indirect or French process, metallic zinc is melted in a graphite crucible and vaporized at temperatures above 907 °C (typically around 1000 °C).
Zinc vapor reacts with the oxygen in the air to give ZnO, accompanied by a drop in its temperature and bright luminescence.
Zinc oxide particles are transported into a cooling duct and collected in a bag house.

This indirect method was popularized by Edme Jean LeClaire of Paris in 1844 and therefore is commonly known as the French process.
Its product normally consists of agglomerated zinc oxide particles with an average size of 0.1 to a few micrometers.
By weight, most of the world's zinc oxide is manufactured via French process.


Direct process:
The direct or American process starts with diverse contaminated zinc composites, such as zinc ores or smelter by-products.
The zinc precursors are reduced (carbothermal reduction) by heating with a source of carbon such as anthracite to produce zinc vapor, which is then oxidized as in the indirect process.
Because of the lower purity of the source material, the final product is also of lower quality in the direct process as compared to the indirect one.


Wet chemical process:
A small amount of industrial production involves wet chemical processes, which start with aqueous solutions of zinc salts, from which zinc carbonate or zinc hydroxide is precipitated.
The solid precipitate is then calcined at temperatures around 800 °C.


Laboratory synthesis:
The red and green colors of these synthetic ZnO crystals result from different concentrations of oxygen vacancies.
Numerous specialised methods exist for producing ZnO for scientific studies and niche applications.
These methods can be classified by the resulting ZnO form (bulk, thin film, nanowire), temperature ("low", that is close to room temperature or "high", that is T ~ 1000 °C), process type (vapor deposition or growth from solution) and other parameters.


Large single crystals (many cubic centimeters) can be grown by the gas transport (vapor-phase deposition), hydrothermal synthesis,[34][48][49] or melt growth.
However, because of the high vapor pressure of ZnO, growth from the melt is problematic.

Growth by gas transport is difficult to control, leaving the hydrothermal method as a preference.
Thin films can be produced by chemical vapor deposition, metalorganic vapour phase epitaxy, electrodeposition, pulsed laser deposition, sputtering, sol–gel synthesis, atomic layer deposition, spray pyrolysis, etc.


Ordinary white powdered zinc oxide can be produced in the laboratory by electrolyzing a solution of sodium bicarbonate with a zinc anode.
Zinc hydroxide and hydrogen gas are produced.
The zinc hydroxide upon heating decomposes to zinc oxide:
Zn + 2 H2O → Zn(OH)2 + H2
Zn(OH)2 → ZnO + H2O


ZnO nanostructures:
Nanostructures of ZnO can be synthesized into a variety of morphologies including nanowires, nanorods, tetrapods, nanobelts, nanoflowers, nanoparticles etc.
Nanostructures can be obtained with most above-mentioned techniques, at certain conditions, and also with the vapor–liquid–solid method.

The synthesis is typically carried out at temperatures of about 90 °C, in an equimolar aqueous solution of zinc nitrate and hexamine, the latter providing the basic environment.
Certain additives, such as polyethylene glycol or polyethylenimine, can improve the aspect ratio of the ZnO nanowires.

Doping of the ZnO nanowires has been achieved by adding other metal nitrates to the growth solution.
The morphology of the resulting nanostructures can be tuned by changing the parameters relating to the precursor composition (such as the zinc concentration and pH) or to the thermal treatment (such as the temperature and heating rate).

Aligned ZnO nanowires on pre-seeded silicon, glass, and gallium nitride substrates have been grown using aqueous zinc salts such as zinc nitrate and zinc acetate in basic environments.
Pre-seeding substrates with ZnO creates sites for homogeneous nucleation of ZnO crystal during the synthesis.

Common pre-seeding methods include in-situ thermal decomposition of zinc acetate crystallites, spincoating of ZnO nanoparticles and the use of physical vapor deposition methods to deposit ZnO thin films.
Pre-seeding can be performed in conjunction with top down patterning methods such as electron beam lithography and nanosphere lithography to designate nucleation sites prior to growth.
Aligned ZnO nanowires can be used in dye-sensitized solar cells and field emission devices.


APPLICATIONS OF ZINC OXIDE:
The applications of zinc oxide powder are numerous, and the principal ones are summarized below. Most applications exploit the reactivity of the oxide as a precursor to other zinc compounds.
For material science applications, zinc oxide has high refractive index, high thermal conductivity, binding, antibacterial and UV-protection properties.

Consequently, it is added into materials and products including plastics, ceramics, glass, cement, rubber, lubricants, paints, ointments, adhesive, sealants, concrete manufacturing, pigments, foods, batteries, ferrites, fire retardants, etc.


Rubber industry:
Between 50% and 60% of ZnO use is in the rubber industry.
Zinc oxide along with stearic acid is used in the sulfur vulcanization of rubber.
ZnO additives also protect rubber from fungi (see medical applications) and UV light.


Ceramic industry:
Ceramic industry consumes a significant amount of zinc oxide, in particular in ceramic glaze and frit compositions.
The relatively high heat capacity, thermal conductivity and high temperature stability of ZnO coupled with a comparatively low coefficient of expansion are desirable properties in the production of ceramics.

ZnO affects the melting point and optical properties of the glazes, enamels, and ceramic formulations.
Zinc oxide as a low expansion, secondary flux improves the elasticity of glazes by reducing the change in viscosity as a function of temperature and helps prevent crazing and shivering.

By substituting ZnO for BaO and PbO, the heat capacity is decreased and the thermal conductivity is increased.
Zinc in small amounts improves the development of glossy and brilliant surfaces.
However, in moderate to high amounts, it produces matte and crystalline surfaces.
With regard to color, zinc has a complicated influence.

Medicine:
Skin treatment:
Zinc oxide as a mixture with about 0.5% iron(III) oxide (Fe2O3) is called calamine and is used in calamine lotion.
Historically the mineral calamine is a mixture of the oxides zincite and hemimorphite.
Zinc oxide is widely used to treat a variety of skin conditions, including atopic dermatitis, contact dermatitis, itching due to eczema, diaper rash and acne.

Zinc oxide is used in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments.
Zinc oxide is often combined with castor oil to form an emollient and astringent, zinc and castor oil cream, commonly used to treat infants.


Zinc oxide is also a component in tape (called "zinc oxide tape") used by athletes as a bandage to prevent soft tissue damage during workouts.

Antibacterial:
Zinc oxide is used in mouthwash products and toothpastes as an anti-bacterial agent proposed to prevent plaque and tartar formation, and to control bad breath by reducing the volatile gases and volatile sulfur compounds (VSC) in the mouth.
Along with zinc oxide or zinc salts, these products also commonly contain other active ingredients, such as cetylpyridinium chloride, xylitol, hinokitiol, essential oils and plant extracts.


Powdered zinc oxide has deodorizing and antibacterial properties.
ZnO is added to cotton fabric, rubber, oral care products, and food packaging.
Enhanced antibacterial action of fine particles compared to bulk material is not exclusive to ZnO and is observed for other materials, such as silver.
This property results from the increased surface area of the fine particles.


Sunscreen:
Zinc oxide is used in sunscreen to absorb ultraviolet light.
It is the broadest spectrum UVA and UVB absorber that is approved for use as a sunscreen by the U.S. Food and Drug Administration (FDA),[84] and is completely photostable.

When used as an ingredient in sunscreen, zinc oxide blocks both UVA (320–400 nm) and UVB (280–320 nm) rays of ultraviolet light.
Zinc oxide and the other most common physical sunscreen, titanium dioxide, are considered to be nonirritating, nonallergenic, and non-comedogenic.
Zinc from zinc oxide is, however, slightly absorbed into the skin.


Many sunscreens use nanoparticles of zinc oxide (along with nanoparticles of titanium dioxide) because such small particles do not scatter light and therefore do not appear white.
The nanoparticles are not absorbed into the skin more than regular-sized zinc oxide particles are, and are only absorbed into the outermost layer of the skin but not into the body.

Dental restoration:
When mixed with eugenol, zinc oxide eugenol is formed, which has applications as a restorative and prosthodontic in dentistry.


Food additive:
Zinc oxide is added to many food products, including breakfast cereals, as a source of zinc, a necessary nutrient.
Zinc sulfate is also used for the same purpose.
Some prepackaged foods also include trace amounts of ZnO even if it is not intended as a nutrient.

Pigment:
Zinc oxide (zinc white) is used as a pigment in paints and is more opaque than lithopone, but less opaque than titanium dioxide.
Zinc oxide is also used in coatings for paper.
Chinese white is a special grade of zinc white used in artists' pigments.

The use of zinc white as a pigment in oil painting started in the middle of 18th century.
Zinc oxide has partly replaced the poisonous lead white and was used by painters such as Böcklin, Van Gogh, Manet, Munch and others.
Zinc oxide is also a main ingredient of mineral makeup (CI 77947).


UV absorber:
Micronized and nano-scale zinc oxide provides strong protection against UVA and UVB ultraviolet radiation, and are consequently used in sunscreens, and also in UV-blocking sunglasses for use in space and for protection when welding, following research by scientists at Jet Propulsion Laboratory (JPL).

Coatings:
Paints containing zinc oxide powder have long been utilized as anticorrosive coatings for metals.
They are especially effective for galvanized iron.
Iron is difficult to protect because its reactivity with organic coatings leads to brittleness and lack of adhesion.
Zinc oxide paints retain their flexibility and adherence on such surfaces for many years.

ZnO highly n-type doped with aluminium, gallium, or indium is transparent and conductive (transparency ~90%, lowest resistivity ~10−4 Ω•cm[97]).
ZnO:Al coatings are used for energy-saving or heat-protecting windows.
The coating lets the visible part of the spectrum in but either reflects the infrared (IR) radiation back into the room (energy saving) or does not let the IR radiation into the room (heat protection), depending on which side of the window has the coating.


Plastics, such as polyethylene naphthalate (PEN), can be protected by applying zinc oxide coating.
The coating reduces the diffusion of oxygen through PEN.
Zinc oxide layers can also be used on polycarbonate in outdoor applications.

The coating protects polycarbonate from solar radiation, and decreases its oxidation rate and photo-yellowing.

Corrosion prevention in nuclear reactors:
Zinc oxide depleted in 64Zn (the zinc isotope with atomic mass 64) is used in corrosion prevention in nuclear pressurized water reactors.
The depletion is necessary, because 64Zn is transformed into radioactive 65Zn under irradiation by the reactor neutrons.

Methane reforming:
Zinc oxide (ZnO) is used as a pretreatment step to remove hydrogen sulfide (H2S) from natural gas following hydrogenation of any sulfur compounds prior to a methane reformer, which can poison the catalyst.
At temperatures between about 230–430 °C (446–806 °F), H2S is converted to water by the following reaction:
H2S + ZnO → H2O + ZnS


Electronics:
Photograph of an operating ZnO UV laser diode and the corresponding device structure.
Flexible gas sensor based on ZnO nanorods and its internal structure.
ITO stands for indium tin oxide and PET for polyethylene terephthalate.

ZnO has wide direct band gap (3.37 eV or 375 nm at room temperature).
Therefore, its most common potential applications are in laser diodes and light emitting diodes (LEDs).
Moreover, ultrafast nonlinearities and photoconductive functions have been reported in ZnO

Some optoelectronic applications of ZnO overlap with that of GaN, which has a similar band gap (~3.4 eV at room temperature).
Compared to GaN, ZnO has a larger exciton binding energy (~60 meV, 2.4 times of the room-temperature thermal energy), which results in bright room-temperature emission from ZnO.

ZnO can be combined with GaN for LED-applications.
For instance, a transparent conducting oxide layer and ZnO nanostructures provide better light outcoupling.
Other properties of ZnO favorable for electronic applications include its stability to high-energy radiation and its ability to be patterned by wet chemical etching.

Radiation resistance makes ZnO a suitable candidate for space applications.
ZnO is the most promising candidate in the field of random lasers to produce an electronically pumped UV laser source.

The pointed tips of ZnO nanorods result in a strong enhancement of an electric field.
Therefore, they can be used as field emitters.


Aluminium-doped ZnO layers are used as transparent electrodes.
The components Zn and Al are much cheaper and less toxic compared to the generally used indium tin oxide (ITO).
One application which has begun to be commercially available is the use of ZnO as the front contact for solar cells or of liquid crystal displays.

Transparent thin-film transistors (TTFT) can be produced with ZnO. As field-effect transistors, they do not need a p–n junction, thus avoiding the p-type doping problem of ZnO.
Some of the field-effect transistors even use ZnO nanorods as conducting channels.

Gas sensors:
Zinc oxide is used in semiconductor gas sensors for detecting airborne compounds such as hydrogen sulfide, nitrogen dioxide, and volatile organic compounds.
ZnO is a semiconductor that becomes n-doped by adsorption of reducing compounds, which reduces the detected electrical resistance through the device, in a manner similar to the widely used tin oxide semiconductor gas sensors.

Zinc oxide is formed into nanostructures such as thin films, nanoparticles, nanopillars or nanowires in order to provide large surface area for interaction with gasses.
The sensors are made selective for specific gasses by doping or surface-attaching materials such as catalytic noble metals.

Piezoelectricity:
The piezoelectricity in textile fibers coated in ZnO have been shown capable of fabricating "self-powered nanosystems" with everyday mechanical stress from wind or body movements.
In 2008 the Center for Nanostructure Characterization at the Georgia Institute of Technology reported producing an electricity generating device (called flexible charge pump generator) delivering alternating current by stretching and releasing zinc oxide nanowires.

This mini-generator creates an oscillating voltage up to 45 millivolts, converting close to seven percent of the applied mechanical energy into electricity.
Researchers used wires with lengths of 0.2–0.3 mm and diameters of three to five micrometers, but the device could be scaled down to smaller size.

In form of a thin film ZnO has been demonstrated in miniaturised high frequency thin film resonators, sensors and filters.



Li-ion battery and supercapacitors:
ZnO is a promising anode material for lithium-ion battery because it is cheap, biocompatible, and environmentally friendly.
ZnO has a higher theoretical capacity (978 mAh g−1) than many other transition metal oxides such as CoO (715 mAh g−1), NiO (718 mAh g−1) and CuO (674 mAh g−1).
ZnO is also used as an electrode in supercapacitors













CHEMICAL AND PHYSICAL PROPERTIES OF ZINC OXIDE:
Chemical formula, ZnO
Molar mass, 81.406 g/mol[1]
Appearance, White solid[1]
Odor, Odorless
Density, 5.6 g/cm3[1]
Melting point, 1,974 °C (3,585 °F; 2,247 K) (decomposes)[1][7]
Boiling point, 2,360 °C (4,280 °F; 2,630 K) (decomposes)
Solubility in water, 0.0004% (17.8°C)[2]
Band gap, 3.2 eV (direct)[3]
Electron mobility, 180 cm2/(V•s)[3]
Magnetic susceptibility (χ), −27.2•10−6 cm3/mol[4]
Thermal conductivity, 0.6 W/(cm•K)[5]
Refractive index (nD), n1=2.013, n2=2.029[6]
Structure[8],
Crystal structure, Wurtzite
Space group, C6v4-P63mc
Lattice constant, a = 3.2495 Å, c = 5.2069 Å
Formula units (Z), 2
Coordination geometry, Tetrahedral
Thermochemistry[9],
Heat capacity (C), 40.3 J•K−1mol−1
Std molar
entropy (S⦵298), 43.65±0.40 J•K−1mol−1
Std enthalpy of
formation (ΔfH⦵298), -350.46±0.27 kJ mol−1
Gibbs free energy (ΔfG⦵), -320.5 kJ mol−1
Enthalpy of fusion (ΔfH⦵fus), 70 kJ/mol
Molecular Weight
81.4 g/mol
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
1
Rotatable Bond Count
0
Exact Mass
79.924056 g/mol
Monoisotopic Mass
79.924056 g/mol
Topological Polar Surface Area
17.1Ų
Heavy Atom Count
2
Formal Charge
0
Complexity
2
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
0
Undefined Bond Stereocenter Count
0
Covalently-Bonded Unit Count
1
Compound Is Canonicalized
Yes
CAS number, 1314-13-2
EC index number, 030-013-00-7
EC number, 215-222-5
Grade, ACS,Reag. Ph Eur
Hill Formula, OZn
Chemical formula, ZnO
Molar Mass, 81.37 g/mol
HS Code, 2817 00 00
Density, 5.61 g/cm³ (20 °C)
Melting Point, 1975 °C
pH value, 7 (50 g/l, H₂O, 20 °C) (slurry)
Bulk density, 200 - 700 kg/m³
Solubility, (20 °C) insoluble
Molecular formula, ZnO
Molar mass, 81.408 g/mol
Appearance, White solid
Odor, odorless
Density, 5.606 g/cm3
Melting point, 1975 °C (decomposes)
Boiling point, 2360 °C
Solubility in water, 0.16 mg/100 mL (30 °C)
Band gap, 3.3 eV (direct)
Refractive index (nD), 2.0041



SAFETY INFORMATION ABOUT ZINC OXIDE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


ZINC OXIDE
Zinc Oxide Zinc Oxide is a wide-band gap semiconductor of the II-VI semiconductor group. The native doping of the semiconductor due to oxygen vacancies or zinc interstitials is n-type. Other favorable properties include good transparency, high electron mobility, wide band gap, and strong room-temperature luminescence. Those properties make ZnO valuable for a variety of emerging applications: transparent electrodes in liquid crystal displays, energy-saving or heat-protecting windows, and electronics as thin-film transistors and light-emitting diodes. Chemical properties of Zinc Oxide Pure Zinc oxide is a white powder, but in nature Zinc oxide occurs as the rare mineral zincite, which usually contains manganese and other impurities that confer a yellow to red color. Crystalline zinc oxide is thermochromic, changing from white to yellow when heated in air and reverting to white on cooling. This color change is caused by a small loss of oxygen to the environment at high temperatures to form the non-stoichiometric Zn1+xO, where at 800 °C, x = 0.00007. Zinc oxide is an amphoteric oxide. It is nearly insoluble in water, but it will dissolve in most acids, such as hydrochloric acid: Zinc oxide + 2 HCl → ZnCl2 + H2O Solid zinc oxide will also dissolve in alkalis to give soluble zincates: Zinc oxide + 2 NaOH + H2O → Na2[Zn(OH)4] Zinc oxide reacts slowly with fatty acids in oils to produce the corresponding carboxylates, such as oleate or stearate. Zinc oxide forms cement-like products when mixed with a strong aqueous solution of zinc chloride and these are best described as zinc hydroxy chlorides. This cement was used in dentistry. Hopeite Zinc oxide also forms cement-like material when treated with phosphoric acid; related materials are used in dentistry. A major component of zinc phosphate cement produced by this reaction is hopeite, Zn3(PO4)2·4H2O. Zinc oxide decomposes into zinc vapor and oxygen at around 1975 °C with a standard oxygen pressure. In a carbothermic reaction, heating with carbon converts the oxide into zinc vapor at a much lower temperature (around 950 °C). Zinc oxide + C → Zn(Vapor) + CO Physical properties of Zinc oxide Zinc oxide crystallizes in two main forms, hexagonal wurtzite and cubic zincblende. The wurtzite structure is most stable at ambient conditions and thus most common. The zincblende form can be stabilized by growing Zinc oxide on substrates with cubic lattice structure. In both cases, the zinc and oxide centers are tetrahedral, the most characteristic geometry for Zn(II). Zinc oxide converts to the rocksalt motif at relatively high pressures about 10 GPa. The many remarkable medical properties of creams containing Zinc oxide can be explained by its elastic softness, which is characteristic of tetrahedral coordinated binary compounds close to the transition to octahedral structures. Hexagonal and zincblende polymorphs have no inversion symmetry (reflection of a crystal relative to any given point does not transform it into itself). This and other lattice symmetry properties result in piezoelectricity of the hexagonal and zincblende Zinc oxide, and pyroelectricity of hexagonal Zinc oxide. The hexagonal structure has a point group 6 mm (Hermann-Mauguin notation) or C6v (Schoenflies notation), and the space group is P63mc or C6v4. The lattice constants are a = 3.25 Å and c = 5.2 Å; their ratio c/a ~ 1.60 is close to the ideal value for hexagonal cell c/a = 1.633. As in most group II-VI materials, the bonding in Zinc oxide is largely ionic (Zn2+–O2−) with the corresponding radii of 0.074 nm for Zn2+ and 0.140 nm for O2−. This property accounts for the preferential formation of wurtzite rather than zinc blende structure, as well as the strong piezoelectricity of Zinc oxide. Because of the polar Zn-O bonds, zinc and oxygen planes are electrically charged. To maintain electrical neutrality, those planes reconstruct at atomic level in most relative materials, but not in Zinc oxide – its surfaces are atomically flat, stable and exhibit no reconstruction. However, studies using wurtzoid structures explained the origin of surface flatness and the absence of reconstruction at Zinc oxide wurtzite surfaces in addition to the origin of charges on Zinc oxide planes. Mechanical properties of Zinc oxide Zinc oxide is a relatively soft material with approximate hardness of 4.5 on the Mohs scale. Its elastic constants are smaller than those of relevant III-V semiconductors, such as GaN. The high heat capacity and heat conductivity, low thermal expansion and high melting temperature of Zinc oxide are beneficial for ceramics. The E2 optical phonon in Zinc oxide exhibits an unusually long lifetime of 133 ps at 10 K. Among the tetrahedrally bonded semiconductors, it has been stated that Zinc oxide has the highest piezoelectric tensor, or at least one comparable to that of GaN and AlN. This property makes it a technologically important material for many piezoelectrical applications, which require a large electromechanical coupling. Therefore Zinc oxide has been in forms of thin film one of the most studied resonator material for thin-film bulk acoustic resonators. Electrical properties of Zinc oxide Zinc oxide has a relatively large direct band gap of ~3.3 eV at room temperature. Advantages associated with a large band gap include higher breakdown voltages, ability to sustain large electric fields, lower electronic noise, and high-temperature and high-power operation. The band gap of Zinc oxide can further be tuned to ~3–4 eV by its alloying with magnesium oxide or cadmium oxide. Most Zinc oxide has n-type character, even in the absence of intentional doping. Nonstoichiometry is typically the origin of n-type character, but the subject remains controversial. An alternative explanation has been proposed, based on theoretical calculations, that unintentional substitutional hydrogen impurities are responsible. Controllable n-type doping is easily achieved by substituting Zn with group-III elements such as Al, Ga, In or by substituting oxygen with group-VII elements chlorine or iodine. Reliable p-type doping of Zinc oxide remains difficult. This problem originates from low solubility of p-type dopants and their compensation by abundant n-type impurities. This problem is observed with GaN and ZnSe. Measurement of p-type in "intrinsically" n-type material is complicated by the inhomogeneity of samples. Current limitations to p-doping limit electronic and optoelectronic applications of Zinc oxide, which usually require junctions of n-type and p-type material. Known p-type dopants include group-I elements Li, Na, K; group-V elements N, P and As; as well as copper and silver. However, many of these form deep acceptors and do not produce significant p-type conduction at room temperature. Electron mobility of Zinc oxide strongly varies with temperature and has a maximum of ~2000 cm2/(V·s) at 80 K. Data on hole mobility are scarce with values in the range 5–30 cm2/(V·s). Zinc oxide discs, acting as a varistor, are the active material in most surge arresters. Production of Zinc oxide For industrial use, Zinc oxide is produced at levels of 105 tons per year by three main processes: Indirect process of Zinc oxide In the indirect or French process, metallic zinc is melted in a graphite crucible and vaporized at temperatures above 907 °C (typically around 1000 °C). Zinc vapor reacts with the oxygen in the air to give Zinc oxide, accompanied by a drop in its temperature and bright luminescence. Zinc oxide particles are transported into a cooling duct and collected in a bag house. This indirect method was popularized by LeClaire (France) in 1844 and therefore is commonly known as the French process. Its product normally consists of agglomerated zinc oxide particles with an average size of 0.1 to a few micrometers. By weight, most of the world's zinc oxide is manufactured via French process. Direct process of Zinc oxide The direct or American process starts with diverse contaminated zinc composites, such as zinc ores or smelter by-products. The zinc precursors are reduced (carbothermal reduction) by heating with a source of carbon such as anthracite to produce zinc vapor, which is then oxidized as in the indirect process. Because of the lower purity of the source material, the final product is also of lower quality in the direct process as compared to the indirect one. Wet chemical process A small amount of industrial production involves wet chemical processes, which start with aqueous solutions of zinc salts, from which zinc carbonate or zinc hydroxide is precipitated. The solid precipitate is then calcined at temperatures around 800 °C. Laboratory synthesis The red and green colors of these synthetic Zinc oxide crystals result from different concentrations of oxygen vacancies. Numerous specialised methods exist for producing Zinc oxide for scientific studies and niche applications. These methods can be classified by the resulting Zinc oxide form (bulk, thin film, nanowire), temperature ("low", that is close to room temperature or "high", that is T ~ 1000 °C), process type (vapor deposition or growth from solution) and other parameters. Large single crystals (many cubic centimeters) can be grown by the gas transport (vapor-phase deposition), hydrothermal synthesis, or melt growth. However, because of high vapor pressure of Zinc oxide, growth from the melt is problematic. Growth by gas transport is difficult to control, leaving the hydrothermal method as a preference. Thin films can be produced by chemical vapor deposition, metalorganic vapour phase epitaxy, electrodeposition, pulsed laser deposition, sputtering, sol-gel synthesis, atomic layer deposition, spray pyrolysis, etc. Ordinary white powdered zinc oxide can be produced in the laboratory by electrolyzing a solution of sodium bicarbonate with a zinc anode. Zinc hydroxide and hydrogen gas are produced. The zinc hydroxide upon heating decomposes to zinc oxide. Zn + 2 H2O → Zn(OH)2 + H2 Zn(OH)2 → Zinc oxide + H2O Zinc oxide nanostructures Nanostructures of Zinc oxide can be synthesized into a variety of morphologies including nanowires, nanorods, tetrapods, nanobelts, nanoflowers, nanoparticles etc. Nanostructures can be obtained with most above-mentioned techniques, at certain conditions, and also with the vapor-liquid-solid method. The synthesis is typically carried out at temperatures of about 90 °C, in an equimolar aqueous solution of zinc nitrate and hexamine, the latter providing the basic environment. Certain additives, such as polyethylene glycol or polyethylenimine, can improve the aspect ratio of the Zinc oxide nanowires. Doping of the Zinc oxide nanowires has been achieved by adding other metal nitrates to the growth solution. The morphology of the resulting nanostructures can be tuned by changing the parameters relating to the precursor composition (such as the zinc concentration and pH) or to the thermal treatment (such as the temperature and heating rate). Aligned Zinc oxide nanowires on pre-seeded silicon, glass, and gallium nitride substrates have been grown using aqueous zinc salts such as zinc nitrate and zinc acetate in basic environments. Pre-seeding substrates with Zinc oxide creates sites for homogeneous nucleation of Zinc oxide crystal during the synthesis. Common pre-seeding methods include in-situ thermal decomposition of zinc acetate crystallites, spincoating of Zinc oxide nanoparticles and the use of physical vapor deposition methods to deposit Zinc oxide thin films. Pre-seeding can be performed in conjunction with top down patterning methods such as electron beam lithography and nanosphere lithography to designate nucleation sites prior to growth. Aligned Zinc oxide nanowires can be used in dye-sensitized solar cells and field emission devices. History of Zinc oxide Zinc compounds were probably used by early humans, in processed and unprocessed forms, as a paint or medicinal ointment, but their composition is uncertain. The use of pushpanjan, probably zinc oxide, as a salve for eyes and open wounds, is mentioned in the Indian medical text the Charaka Samhita, thought to date from 500 BC or before. Zinc oxide ointment is also mentioned by the Greek physician Dioscorides (1st century AD). Galen suggested treating ulcerating cancers with zinc oxide, as did Avicenna in his The Canon of Medicine. Zinc oxide is no longer used for treating skin cancer, though it is still used as an ingredient in products such as baby powder and creams against diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. The Romans produced considerable quantities of brass (an alloy of zinc and copper) as early as 200 BC by a cementation process where copper was reacted with zinc oxide. The zinc oxide is thought to have been produced by heating zinc ore in a shaft furnace. This liberated metallic zinc as a vapor, which then ascended the flue and condensed as the oxide. This process was described by Dioscorides in the 1st century AD. Zinc oxide has also been recovered from zinc mines at Zawar in India, dating from the second half of the first millennium BC. From the 12th to the 16th century zinc and zinc oxide were recognized and produced in India using a primitive form of the direct synthesis process. From India, zinc manufacture moved to China in the 17th century. In 1743, the first European zinc smelter was established in Bristol, United Kingdom. Around 1782 Louis-Bernard Guyton de Morveau proposed replacing lead white with zinc oxide. The main usage of zinc oxide (zinc white) was in paints and as an additive to ointments. Zinc white was accepted as a pigment in oil paintings by 1834 but it did not mix well with oil. This problem was solved by optimizing the synthesis of Zinc oxide. In 1845, LeClaire in Paris was producing the oil paint on a large scale, and by 1850, zinc white was being manufactured throughout Europe. The success of zinc white paint was due to its advantages over the traditional white lead: zinc white is essentially permanent in sunlight, it is not blackened by sulfur-bearing air, it is non-toxic and more economical. Because zinc white is so "clean" it is valuable for making tints with other colors, but it makes a rather brittle dry film when unmixed with other colors. For example, during the late 1890s and early 1900s, some artists used zinc white as a ground for their oil paintings. All those paintings developed cracks over the years. In recent times, most zinc oxide was used in the rubber industry to resist corrosion. In the 1970s, the second largest application of Zinc oxide was photocopying. High-quality Zinc oxide produced by the "French process" was added to photocopying paper as a filler. This application was soon displaced by titanium. Applications of Zinc oxide The applications of zinc oxide powder are numerous, and the principal ones are summarized below. Most applications exploit the reactivity of the oxide as a precursor to other zinc compounds. For material science applications, zinc oxide has high refractive index, high thermal conductivity, binding, antibacterial and UV-protection properties. Consequently, it is added into materials and products including plastics, ceramics, glass, cement, rubber, lubricants, paints, ointments, adhesive, sealants, concrete manufacturing, pigments, foods, batteries, ferrites, fire retardants, etc. Rubber manufacture of Zinc oxide Between 50% and 60% of Zinc oxide use is in the rubber industry. Zinc oxide along with stearic acid is used in the vulcanization of rubber Zinc oxide additive also protect rubber from fungi (see medical applications) and UV light. Ceramic industry Ceramic industry consumes a significant amount of zinc oxide, in particular in ceramic glaze and frit compositions. The relatively high heat capacity, thermal conductivity and high temperature stability of Zinc oxide coupled with a comparatively low coefficient of expansion are desirable properties in the production of ceramics. Zinc oxide affects the melting point and optical properties of the glazes, enamels, and ceramic formulations. Zinc oxide as a low expansion, secondary flux improves the elasticity of glazes by reducing the change in viscosity as a function of temperature and helps prevent crazing and shivering. By substituting Zinc oxide for BaO and PbO, the heat capacity is decreased and the thermal conductivity is increased. Zinc in small amounts improves the development of glossy and brilliant surfaces. However, in moderate to high amounts, it produces matte and crystalline surfaces. With regard to color, zinc has a complicated influence. Medicine Zinc oxide as a mixture with about 0.5% iron(III) oxide (Fe2O3) is called calamine and is used in calamine lotion. Two minerals, zincite and hemimorphite, have been historically called calamine. When mixed with eugenol, a ligand, zinc oxide eugenol is formed, which has applications as a restorative and prosthodontic in dentistry. Reflecting the basic properties of Zinc oxide, fine particles of the oxide have deodorizing and antibacterial properties and for that reason are added into materials including cotton fabric, rubber, oral care products, and food packaging. Enhanced antibacterial action of fine particles compared to bulk material is not exclusive to Zinc oxide and is observed for other materials, such as silver. This property results from the increased surface area of the fine particles. Zinc oxide is used in mouthwash products and toothpastes as an anti-bacterial agent proposed to prevent plaque and tartar formation, and to control bad breath by reducing the volatile gases and volatile sulphur compounds (VSC) in the mouth. Along with zinc oxide or zinc salts, these products also commonly contain other active ingredients, such as cetylpyridinium chloride, xylitol, hinokitiol, essential oils and plant extracts. Zinc oxide is widely used to treat a variety of skin conditions, including atopic dermatitis, contact dermatitis, itching due to eczema, diaper rash and acne. Zinc oxide is also often added into sunscreens. It is used in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. It is also a component in tape (called "zinc oxide tape") used by athletes as a bandage to prevent soft tissue damage during workouts. Zinc oxide can be used in ointments, creams, and lotions to protect against sunburn and other damage to the skin caused by ultraviolet light (see sunscreen). It is the broadest spectrum UVA and UVB absorber that is approved for use as a sunscreen by the U.S. Food and Drug Administration (FDA), and is completely photostable. When used as an ingredient in sunscreen, zinc oxide blocks both UVA (320–400 nm) and UVB (280–320 nm) rays of ultraviolet light. Zinc oxide and the other most common physical sunscreen, titanium dioxide, are considered to be nonirritating, nonallergenic, and non-comedogenic. Zinc from zinc oxide is, however, slightly absorbed into the skin. Many sunscreens use nanoparticles of zinc oxide (along with nanoparticles of titanium dioxide) because such small particles do not scatter light and therefore do not appear white. The nanoparticles are not absorbed into the skin more than regular-sized zinc oxide particles are, and are only absorbed into the outermost layer of the skin but not into the body. Zinc oxide nanoparticles can enhance the antibacterial activity of ciprofloxacin. It has been shown that nano Zinc oxide that has an average size between 20 nm and 45 nm can enhance the antibacterial activity of ciprofloxacin against Staphylococcus aureus and Escherichia coli in vitro. The enhancing effect of this nanomaterial is concentration dependent against all test strains. This effect may be due to two reasons. First, zinc oxide nanoparticles can interfere with NorA protein, which is developed for conferring resistance in bacteria and has pumping activity that mediate the effluxing of hydrophilic fluoroquinolones from a cell. Second, zinc oxide nanoparticles can interfere with Omf protein, which is responsible for the permeation of quinolone antibiotics into the cell. Cigarette filters Zinc oxide is a component of cigarette filters. A filter consisting of charcoal impregnated with zinc oxide and iron oxide removes significant amounts of hydrogen cyanide (HCN) and hydrogen sulfide (H2S) from tobacco smoke without affecting its flavor. Food additive Zinc oxide is added to many food products, including breakfast cereals, as a source of zinc, a necessary nutrient. (Zinc sulfate is also used for the same purpose.) Some prepackaged foods also include trace amounts of Zinc oxide even if it is not intended as a nutrient. Zinc oxide was linked to dioxin contamination in pork exports in the 2008 Chilean pork crisis. The contamination was found to be due to dioxin contaminated zinc oxide used in pig feed. Pigment Zinc white is used as a pigment in paints and is more opaque than lithopone, but less opaque than titanium dioxide. It is also used in coatings for paper. Chinese white is a special grade of zinc white used in artists' pigments. The use of zinc white (zinc oxide) as a pigment in oil painting started in the middle of 18th century. It has partly replaced the poisonous lead white and was used by painters such as Böcklin, Van Gogh, Manet, Munch and others. It is also a main ingredient of mineral makeup (CI 77947). UV absorber Micronized and nano-scale zinc oxide and titanium dioxide provide strong protection against UVA and UVB ultraviolet radiation, and are used in suntan lotion, and also in UV-blocking sunglasses for use in space and for protection when welding, following research by scientists at Jet Propulsion Laboratory (JPL). Coatings Paints containing zinc oxide powder have long been utilized as anticorrosive coatings for metals. They are especially effective for galvanized iron. Iron is difficult to protect because its reactivity with organic coatings leads to brittleness and lack of adhesion. Zinc oxide paints retain their flexibility and adherence on such surfaces for many years. Zinc oxide highly n-type doped with aluminium, gallium, or indium is transparent and conductive (transparency ~90%, lowest resistivity ~10−4 Ω·cm). Zinc oxide:Al coatings are used for energy-saving or heat-protecting windows. The coating lets the visible part of the spectrum in but either reflects the infrared (IR) radiation back into the room (energy saving) or does not let the IR radiation into the room (heat protection), depending on which side of the window has the coating. Plastics, such as polyethylene naphthalate (PEN), can be protected by applying zinc oxide coating. The coating reduces the diffusion of oxygen with PEN. Zinc oxide layers can also be used on polycarbonate in outdoor applications. The coating protects polycarbonate from solar radiation, and decreases its oxidation rate and photo-yellowing. Corrosion prevention in nuclear reactors Zinc oxide depleted in 64Zn (the zinc isotope with atomic mass 64) is used in corrosion prevention in nuclear pressurized water reactors. The depletion is necessary, because 64Zn is transformed into radioactive 65Zn under irradiation by the reactor neutrons. Methane reforming Zinc oxide (ZnO) is used as a pretreatment step to remove hydrogen sulfide (H2S) from natural gas following hydrogenation of any sulfur compounds prior to a methane reformer, which can poison the catalyst. At temperatures between about 230–430 °C (446–806 °F), H2S is converted to water by the following reaction: H2S + Zinc oxide → H2O + ZnS The zinc sulfide (ZnS) is replaced with fresh zinc oxide when the zinc oxide has been consumed. Potential applications of Zinc oxide Electronics Zinc oxide has wide direct band gap (3.37 eV or 375 nm at room temperature). Therefore, its most common potential applications are in laser diodes and light emitting diodes (LEDs). Some optoelectronic applications of Zinc oxide overlap with that of GaN, which has a similar band gap (~3.4 eV at room temperature). Compared to GaN, Zinc oxide has a larger exciton binding energy (~60 meV, 2.4 times of the room-temperature thermal energy), which results in bright room-temperature emission from Zinc oxide. Zinc oxide can be combined with GaN for LED-applications. For instance as transparent conducting oxide layer and Zinc oxide nanostructures provide better light outcoupling. Other properties of Zinc oxide favorable for electronic applications include its stability to high-energy radiation and its possibility to be patterned by wet chemical etching. Radiation resistance makes Zinc oxide a suitable candidate for space applications. Zinc oxide is the most promising candidate in the field of random lasers to produce an electronically pumped UV laser source. The pointed tips of Zinc oxide nanorods result in a strong enhancement of an electric field. Therefore, they can be used as field emitters. Aluminium-doped Zinc oxide layers are used as transparent electrodes. The components Zn and Al are much cheaper and less toxic compared to the generally used indium tin oxide (ITO). One application which has begun to be commercially available is the use of Zinc oxide as the front contact for solar cells or of liquid crystal displays. Transparent thin-film transistors (TTFT) can be produced with Zinc oxide. As field-effect transistors, they even may not need a p–n junction, thus avoiding the p-type doping problem of Zinc oxide. Some of the field-effect transistors even use Zinc oxide nanorods as conducting channels. Zinc oxide nanorod sensor Zinc oxide nanorod sensors are devices detecting changes in electric current passing through zinc oxide nanowires due to adsorption of gas molecules. Selectivity to hydrogen gas was achieved by sputtering Pd clusters on the nanorod surface. The addition of Pd appears to be effective in the catalytic dissociation of hydrogen molecules into atomic hydrogen, increasing the sensitivity of the sensor device. The sensor detects hydrogen concentrations down to 10 parts per million at room temperature, whereas there is no response to oxygen. Zinc oxide have been used as immobilization layers in imunosensors enabling the distribution of antibodies across the entire region probed by the measuring electric field applied to the microelectrodes. Spintronics Zinc oxide has also been considered for spintronics applications: if doped with 1–10% of magnetic ions (Mn, Fe, Co, V, etc.), Zinc oxide could become ferromagnetic, even at room temperature. Such room temperature ferromagnetism in Zinc oxide:Mn has been observed, but it is not clear yet whether it originates from the matrix itself or from secondary oxide phases. Piezoelectricity The piezoelectricity in textile fibers coated in Zinc oxide have been shown capable of fabricating "self-powered nanosystems" with everyday mechanical stress from wind or body movements. In 2008 the Center for Nanostructure Characterization at the Georgia Institute of Technology reported producing an electricity generating device (called flexible charge pump generator) delivering alternating current by stretching and releasing zinc oxide nanowires. This mini-generator creates an oscillating voltage up to 45 millivolts, converting close to seven percent of the applied mechanical energy into electricity. Researchers used wires with lengths of 0.2–0.3 mm and diameters of three to five micrometers, but the device could be scaled down to smaller size. Zinc oxide as anode of Li-ion battery In form of a thin film Zinc oxide has been demonstrated in miniaturised high frequency thin film resonators, sensors and filters. Li-ion battery Zinc oxide is a promising anode material for lithium-ion battery because it is cheap, biocompatible, and environmentally friendly. Zinc oxide has a higher theoretical capacity (978 mAh g−1) than many other transition metal oxides such as CoO (715 mAh g−1), NiO (718 mAh g−1) and CuO (674 mAh g−1). Safety of Zinc oxide As a food additive, zinc oxide is on the U.S. FDA's list of generally recognized as safe, or GRAS, substances. Zinc oxide itself is non-toxic; it is hazardous, however, to inhale zinc oxide fumes, such as generated when zinc or zinc alloys are melted and oxidized at high temperature. This problem occurs while melting alloys containing brass because the melting point of brass is close to the boiling point of zinc.Exposure to zinc oxide in the air, which also occurs while welding galvanized (zinc plated) steel, can result in a malady called metal fume fever. For this reason, typically galvanized steel is not welded, or the zinc is removed first. Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced synthetically. It is also widely used to treat a variety of other skin conditions, in products such as baby powder and barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments. Zinc oxide is mildly astringent and is used topically as a soothing and protective application in eczema and slight excoriations, in wounds, and for hemorrhoids. It is also used with coal tar or ichthammol in the treatment eczema. Zinc oxide is used as the basis for the production of a number of dental cements. Mixed with phosphoric acid it forms a hard material composed largely of zinc phosphate; mixed with clove oil or eugenol, it is used as temporary dental filling. Pharmacologic levels of zinc as zinc oxide have consistently been found to increase pig performance during the postweaning period. In some instances, high levels of zinc oxide have been reported to reduce the incidence and severity of postweaning diarrhea. Responses to zinc oxide and antibiotics seem to be additive in nature, much like the responses to high copper and antibiotics; however, there is no advantage in including high copper and high zinc in the same diet. Zinc oxide accounts for the largest use of zinc compounds, and is used primarily by the rubber industry as a vulcanization activator and accelerator and to slow rubber aging by neutralizing sulfur and organic acids formed by oxidation. It also acts in rubber as a reinforcing agent, a heat conductor, a white pigment, and an absorber of UV light. In paints, zinc oxide serves as a mildewstat, acid buffer, and a pigment. It is used in animal feed as a zinc supplement and as a fertilizer additive for zinc-deficient soils. Zinc oxide is used in cosmetics and drugs primarily for its fungicide properties, and in dentistry in dental cements. It is also used in ceramics, in glass manufacture, as a catalyst in organic synthesis, and in coated photocopy paper. Two processes are used to produce metallic zinc from the ore concentrates that are not subjected to caustic soda leaching. In one process, the ore concentrate containing zinc sulfide is roasted in the presence of air to produce zinc oxide, which is combined with coke or coal and retorted to approximately 1,100 °C to produce metallic zinc. In the other process, the roasted zinc oxide is leached with sulfuric acid, and the solution is electrolyzed to produce zinc of >99.9% purity. Zinc oxide is also produced industrially from purified solutions of zinc sulfate or chloride by precipitating the basic carbonate, which is then washed, filtered, and finally calcined. This method produces a grade of zinc oxide with a high specific surface area. Products of this type are also obtained from waste hydroxides which are purified by a chemical route and then calcined. Residues of zinc oxide are exempted from the requirement of a tolerance when used as a coating agent in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops or to raw agricultural commodities after harvest.
ZINC PEROXIDE
Zinc orthophosphate; Phosphoric acid, zinc salt (2:3); Zinc Phosphate; Trizinc bis(orthophosphate); Trizinkbis(orthophosphat) (German); Bis(ortofosfato) de tricinc (Spanish); Bis(orthophosphate) de trizinc (French); cas no: 7779-90-0
ZINC PHOSPHATE
CAS Number: 7779-90-0
PubChem CID: 24519
Molecular Weight: 386.1
Linear Formula: Zn3(PO4)2



APPLICATIONS


Zinc phosphate dental cement is one of the oldest and widely used dental cements.
However, Zinc Phosphate is commonly used for luting permanent metal and zirconium dioxide[4][5][6][7][8][9] restorations and as a base for dental restorations.
Zinc phosphate cement is used for cementation of inlays, crowns, bridges, and orthodontic appliances and occasionally as a temporary restoration.

Zinc Phosphate is prepared by mixing zinc oxide and magnesium oxide powders with a liquid consisting principally of phosphoric acid, water, and buffers.
Further, Zinc Phosphate is the standard cement to measure against.

Zinc Phosphate has the longest track record of use in dentistry.
More to that, Zinc Phosphate is still commonly used; however, resin-modified glass ionomer cements are more convenient and stronger when used in a dental setting.

Zinc Phosphate is used for coatings.
We can divide zinc phosphate coatings into three sections according to application areas:

Application for preventing abrasion caused by friction before metal forming processes such as cold drawing, cold forging, deep drawing,
Application for increasing paint adhesion before electrostatic powder coating and wet painting,
Application for increasing wear resistance and corrosion resistance with protective lubrication.

When Zinc Phosphate is used before forming of metals, coating weight of 5 - 15 g/m2 is usually required.
Zinc Phosphate is most commonly used in wire and tube drawing processes.
The Zinc Phosphate layer is firmly attached to the metal surface and reduces friction in the dies and molds during the cold drawing process, allowing these operations to be carried out easily.

Zinc Phosphate layer remaining on the surface after the drawing operation creates high corrosion resistance during storage and transportation and prevents rusting.
Further, Zinc Phosphate coating is of great importance in high carbon wire drawing industry such as steel rope, spring, welding wire, pc wire, pc strand production.

Zinc Phosphate provides continuity on the surface for multiple drawing operations and enables high drawing speeds.
Moreover, Zinc Phosphate enables difficult cold forging operations in the production of bolts and screws and ensures long service life of molds.

If zinc phosphate coating will be applied under paint, a coating in the range of 2-6 g/m2 must be obtained on the metal part.
Making a uniform coating with thin crystal structure is important in terms of adhesion to paint and to provide corrosion resistance in harsh environmental conditions.

The desired coating weight for protective oil application is in the range of 10-35 g/m2.
Zinc phosphate coating with coarse crystal structure and high coating weight retains the protective oil and provides an effective corrosion resistance.

Zinc Phosphate is widely used for auto parts, fasteners and machine parts.

Zinc phosphate is used to produce corrosion resistant coatings that are typically applied either as part of an electroplating process or as a primer pigment.
Furthermore, Zinc Phosphate reacts moderately with water and is acid soluble with zinc sources, allowing it to have good moisture resistance and galvanic substitution properties.
When used in a micronized form for pigmentation Zinc Phosphate is suitable for a wide range of primer applications.

Zinc phosphate is also a key component of zinc orthophosphate hydrate, which is a protective compound that is easy to disperse.
The low solubility behavior of Zinc Phosphate provides high compatibility with both solvent- and water-based resins.

Zinc Phosphate is used in dental cements, phosphors, and coatings of steel and aluminum
Zinc Phosphate is the most important phosphate-containing pigment--reacts with iron to produce a protective film.

Some uses of Zinc Phosphate:
Corrosion inhibitor
Dyes
Filler
Paint additives and coating additives not described by other categories
Pigment
Stabilizing agent
Surface modifier
Adhesion/cohesion promoter
Agricultural chemicals (non-pesticidal)
Plating agents and surface treating agents

Zinc Phosphate is used in the manufacturing of dyes.
Further, Zinc Phosphate is used as a plating agent as well as a surface treating agent.
Zinc Phosphate is used as a corrosion inhibitor.

Zinc Phosphate is used as an additive in paints.
Moreover, Zinc Phosphate is used in water treatment products.

Zinc Phosphate is an anti-scaling agent.
More to that, Zinc Phosphate is used in preparing rubber products.


Other uses of Zinc Phosphate:

Materials used for construction (e.g. flooring, tile, sinks, bathtubs, mirrors, wall materials/drywall, wall-to-wall carpets)
Corrosion inhibitor
Furniture and furnishings
Items used to furnish a home or workplace, e.g. tables, chairs, sofa, outdoor patio furniture, sofa cover, hammock, mattress, area rug
Adhesives and adhesive removers
Extender pigment
Filler
Filler
Multipurpose adhesive
General purpose repair adhesives including all purpose glues, super glue, and epoxies; not including wood glues
Paint/stain and related products
Home improvement paints, excluding or not specified as oil-, solvent-, or water-based paints
Paints applied to hard surfaces that are intended to be painted over and that improve adhesion, coverage, or prevent the bleeding through of stains
Products used on wooden surfaces, including decks, to impart transparent or semitransparent color
Dental care
Toothpastes and dentrifices
Inhibitor

Zinc phosphate coating is a crystallized conversion coating formed on the metal surface.
The Zinc Phosphate coating process is based on the chemical reaction between the metal and the weak acidic phosphate fluid to form insoluble phosphate crystals on the surface of the part.

Zinc Phosphate coating is used as a pretreatment before painting, to increase corrosion resistance and to provide a better adhesion surface for coating systems.
When used alone or with oil, Zinc Phosphate reduces the friction characteristics of the moving components or threaded parts.

Although Zinc Phosphate is generally referred to as a coating, since phosphate alone has a low rust resistance, it must be used in combination with oil or top lacquer applications in order to be used as a protection against corrosion.
Zinc phosphate can be applied to Ferrous metals, but it has no effect on Stainless Steel.

Advantages of Zinc Phosphate:

Zinc Phosphate provides corrosion resistance.
Further, Zinc Phosphate provides a good adhesion surface for Paint and Organic coatings.
Zinc Phosphate helps for the reduction of friction coefficient when applied with oil.

Zinc phosphate enhances paint adhesion by giving the paint something to bond to securely.
Moreover, Zinc Phosphate reduces paint-to-metal reactions and forms a barrier between the substrate and the paint.
Zinc phosphate also reduces general surface corrosion on metal substrates and reduces underfilm delamination in the event of damage to the paint film.

There are three types of Zinc Phosphate coatings.
Iron phosphate is a lightweight amorphous coating.
It generally has a coating weight between 15-100 mg/ft2 and typically used as paint base for low-corrosion environments.

A modified zinc phosphate coating is a medium weight crystalline phosphate coating.
It has a coating weight between 150-350 mg/ft2.
It is typically used as paint base for high-corrosion environments.

A heavy zinc phosphate coating produces a very heavy coating weight, typically between 700-3,500 mg/ft2.
It is used for unpainted applications.
When applying a zinc phosphate coating to metal, remember that high temperatures cause excessive phosphate sludge, resulting in high chemical and maintenance costs.
An efficient zinc phosphate coating can have several long-term benefits, including fewer rejects, higher throughput, decreased downtime, and lower maintenance costs.

Zinc phosphate is widely used in automotive and military applications, but is used to a lesser extent in general industry where high paint performance may not be required.
Since neither iron phosphate nor green technologies can out-perform zinc phosphate, zinc phosphate will be in use for many years to come.

The big change will come in the future when new technologies perform as well as zinc phosphate combined with an economic incentive of cost reduction.
At that point, we will see a major shift to green technologies.



DESCRIPTION


Zinc phosphate is an inorganic compound with the formula Zn3(PO4)2.
This white powder is widely used as a corrosion resistant coating on metal surfaces either as part of an electroplating process or applied as a primer pigment (see also red lead).

Zinc Phosphate has largely displaced toxic materials based on lead or chromium, and by 2006 it had become the most commonly used corrosion inhibitor.
Furthermore, Zinc phosphate coats better on a crystalline structure than bare metal, so a seeding agent is often used as a pre-treatment.
One common agent is sodium pyrophosphate.

Zinc Phosphate appears in the form of white crystals.
The molecular weight of Zinc Phosphate is 386.11 g/mol.

The density of Zinc Phosphate is 3.998 g/cm3.
The melting point of Zinc Phosphate is 900°C.
Zinc Phosphate is a nonflammable compound.

Zinc Phosphate is an inorganic compound that combines phosphorus with zinc.

Zinc Phosphate is used in rodenticide baits.
When an animal eats the bait, the acid in the animal's stomach turns the zinc phosphide into phosphine.
Zinc Phosphate causes a very toxic gas.

Zinc Phosphate is also released by aluminum phosphide and magnesium phosphide.
These are used as fumigants in stored grain.

Zinc Phosphate has been registered for use in pesticide products in the United States since 1947.

Natural forms of Zinc Phosphate include minerals hopeite and parahopeite.
A somewhat similar mineral is natural hydrous zinc phosphate called tarbuttite, Zn2(PO4)(OH).
Both are known from oxidation zones of Zn ore beds and were formed through oxidation of sphalerite by the presence of phosphate-rich solutions.
The anhydrous form of Zinc Phosphate has not yet been found naturally.

Zinc phosphate is an inorganic chemical compound consisting of zinc, phosphorous and oxygen with the chemical formula Zn3(PO4)2.
Furthermore, Zinc Phosphate is commonly used as a corrosion inhibitor when applied to metallic surfaces.

Zinc Phosphate is a material used for cementation of inlays, crowns, bridges, and orthodontic appliances and occasionally as a temporary restoration.
Moreover, Zinc Phosphate is prepared by mixing zinc oxide and magnesium oxide powders with a liquid consisting principally of phosphoric acid, water, and buffers.

Zinc Phosphate is an inorganic chemical compound having a chemical name Zinc Phosphate.
The other names for Zinc Phosphate are Zinc orthophosphate, Trizinc phosphate, and Trizinc diphosphate.
This white powder compound is widely used as a corrosion-resistant coating, which is applied on the metal surfaces, which are put as a part of electroplating or as a primer pigment.

Zinc Phosphate is a universal lead-free and chromium-free inorganic corrosion inhibitor designed for water-based and solvent-based coatings.
Further, Zinc Phosphate exhibits a high degree of versatility because of its narrow particle size distribution: upper particle size limit of 20 microns, mean particle size of 5 microns.

Zinc Phosphate is an important antioxidant nutrient and functions as a cofactor for numerous enzymes, including those involved in DNA and RNA replication, protein synthesis, insulin production and brain development.
Despite the importance of this mineral, our bodies cannot store excess Zinc as it naturally does with some other minerals and vitamins, so continuous dietary intake is required.

When compared to the bare metal, the trizinc phosphate coats better on a crystalline structure.
Thus, a seeding agent like sodium pyrophosphate is used frequently as a pre-treatment.
Zinc Phosphate has largely displaced toxic materials based on chromium or lead.

Zinc Phosphate had become one of the most commonly used corrosion inhibitors by 2006.
The common agent of this Zinc Phosphate is sodium pyrophosphate.

Zinc Phosphate is a moderately water and acid soluble Zinc source for uses compatible with Phosphates.

Zinc Phosphate is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.



PROPERTIES


Chemical formula: H4O12P2Zn3
Molar mass: 454.11 g·mol−1
Appearance: white solid
Density: 3.998 g/cm3
Melting point: 900 °C (1,650 °F; 1,170 K)
Boiling point: 158 °C (316 °F; 431 K)
Solubility in water: insoluble
Magnetic susceptibility (χ): −141.0·10−6 cm3/mol

Refractive index (nD): 1.595
Molecular Weight: 386.1
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 8
Rotatable Bond Count: 0
Exact Mass: 383.69116
Monoisotopic Mass: 381.69427
Topological Polar Surface Area: 173 Ų
Heavy Atom Count: 13
Formal Charge: 0
Complexity: 36.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 5
Compound Is Canonicalized: Yes



SYNONYMS


Zinc Phosphate
7779-90-0
Trizinc phosphate
Phosphoric acid, zinc salt
Trizinc diphosphate
Zinc orthophosphate
trizinc;diphosphate
Trizinc bis(orthophosphate)
Tribasic zinc phosphate
Phosphoric acid, zinc salt (2:3)
Zincphosphate
704TVM
13847-22-8
14485-28-0
1E2MCT2M62
Delaphos
Delaphos 2M
Bonderite 40
Granodine 80
Microphos 90
Granodine 16NC
Zinc acid phosphate
Bonderite 181
Bonderite 880
Heucophos ZP 10
Pigment White 32
Sicor ZNP/M
Sicor ZNP/S
Phosphinox PZ 06
Virchem 931
Fleck's Extraordinary
LF Bowsei PW 2
Neutral zinc phosphate
Weather coat 1000
ZP-DL
ZP-SB
Zinc phosphate (3:2)
Man-Gill 51339
Man-Gill 51355
C.I. Pigment White 32
ZINC PHOSPHATE CEMENT
Fleck's Extraordinary Cement
LF-PW 2
Zinc ortho-phosphate
EINECS 231-944-3
UNII-1E2MCT2M62
C.I. 77964
J 0852
EINECS 237-583-8
zinc(II) phosphate
Zinc phosphate-tribasic
EC 231-944-3
ZINC PHOSPHATE [MI]
ZINC PHOSPHATE [INCI]
ZINC PHOSPHATE [VANDF]
CHEMBL2286756
DTXSID3064807
ZINC PHOSPHATE [WHO-DD]
Zinc phosphate, analytical standard
EINECS 238-280-3
Phosphoric acid, zinc salt (1:?)
MFCD00036282
AKOS024418785
FT-0696571
Zinc phosphate, 99.998% trace metals basis
Q59714
Zinc phosphate (ortho), 99.995% (metals basis)
2,2-(1,2-Ethenediyldi-4,1-phenylene)bisbenzoxazole















ZINC PHOSPHATE
Zinc; Zn; Zinc dust; cinc cas no: 7440-66-6
ZINC POWDER
Zinc bis-(2-Pyridinethiol-1-oxide); ZNPT; ZPT; Zinc, bis(2-pyridylthio)-, N,N'-dioxide; 1-Hydroxy-2-pyridinethione, zinc salt; 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex; 2-Mercaptopyridine 1-oxide Zinc Salt; 2-Pyridinethiol N-oxide zinc salt; 2-Pyridinethiol, 1-oxide, zinc salt; Zinc, Bis(2-pyridinylthio)-, N,N'-dioxide; Zinc, Bis(2-pyridylthio)-, 1,1'-dioxide; Zinc, Bis(2-pyridylthio)-, N,N'-dioxide; Zincpolyanemine; Zinksalz Des 1-hydroxi-2-pyridinthion CAS NO:13463-41-7
ZINC PYRITHIONE
Zinc pyrithione is a preservative that is also used in anti-dandruff shampoos for anti-fungal functions.
Zinc pyrithione works to treat dandruff at the root cause by functioning as a fungicide with specific efficacy against Malassezia.
Zinc pyrithione has anti-fungal properties and appears as a crystalline powder in raw form that is white or slightly yellow in color.

CAS Number: 68890-66-4
EC Number: 272-574-2
Molecular Formula: C14H23NO2·C2H7NO
Molecular Weight: 298.42

PIROCTONE OLAMINE, 68890-66-4, Octopirox, Piroctone ethanolamine, Kopirox, Piroctoneolamine, Octopyrox, Piroctone ethanolamine salt, Piroctone olamine [USAN], C14H23NO2.C2H7NO, 2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, EINECS 272-574-2, UNII-A4V5C6R9FB, A4V5C6R9FB, NSC-759894, PIROCTONE ETHANOLAMINE SALT (1:1), Piroctone olamine (USAN), EC 272-574-2, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one 2-aminoethanol salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethan-1-ol (1:1), Octopirox (TN), SCHEMBL2843, CHEMBL2107154, PIROCTONE OLAMINE [INCI], PIROCTONE OLAMINE [MART.], PIROCTONE OLAMINE [USP-RS], AMY40819, BCP29912, HY-B1345, MFCD01690792, s5213, Piroctone olamine, analytical standard, AKOS025149526, CCG-267454, CS-7659, NSC 759894, PIROCTONE ETHANOLAMINE [WHO-DD], AS-15254, C14-H23-N-O2.C2-H7-N-O, LS-133057, FT-0653357, P2178, D05505, Piroctone ethanolamine salt; Octopirox; Kopirox, PIROCTONE ETHANOLAMINE SALT (1:1) [MI], A836281, Q412572, W-104652, 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone Ethanolamine, Piroctone olamine, United States Pharmacopeia (USP) Reference Standard, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-1,2-dihydropyridin-2-one; 2-aminoethan-1-ol, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2 pyridon and its monoethanolamine salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt, 1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)-2-PYRIDONE MONOETHANOLAMINE, (+/-)-, 1- hydroxy- 4- methyl- 6- (2, 4, 4- trimethylpentyl)pyridin- 2(1H)- one, compound with 2- aminoethanol (1:1), Ethanol, 2-amino-, compd. with 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone (1:1) (9CI); 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone monoethanolamine salt; Octopirox; Octopyrox; Piroctone ethanolamine salt; Piroctone olamine, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinon --2-aminoethanol (1:1) [German] [ACD/IUPAC Name], 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinon--2-aminoethanol(1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone - 2-aminoethanol (1:1) [ACD/IUPAC Name], 1-Hydroxy-4-méthyl-6-(2,4,4-triméthylpentyl)-2(1H)-pyridinone - 2-aminoéthanol (1:1) [French] [ACD/IUPAC Name], 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridinone 2-Aminoethanol Salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one - 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compd. with 2-aminoethanol (1:1) [ACD/Index Name], 272-574-2 [EINECS], 68890-66-4 [RN], A4V5C6R9FB, MFCD01690792, octopirox [Trade name], Piroctone ethanolamine, Piroctone ethanolamine salt, Piroctone olamine [Wiki], UNII:A4V5C6R9FB, [68890-66-4] [RN], 1-Aminoethane, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt, 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone compound with 2-aminoethanol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanol ammonium salt, 1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one compound with 2-aminoethan-1-ol (1:1), 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1), 2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compound with 2-aminoethanol (1:1), 2-aminoethanol and 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, 2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one, 2-hydroxyethylammonium; 4-methyl-1-oxido-6-(2,4,4-trimethylpentyl)-2-pyridinone, Octopirox| Piroctone ethanolamine, Piroctone, Piroctone olamin, PIROCTONE OLEAMINE, QA-6124

Zinc pyrithione is a compound sometimes used in the treatment of fungal infections.
Zinc pyrithione is the ethanolamine salt of the hydroxamic acid derivative piroctone.

Zinc pyrithione is often used in anti-dandruff shampoo as a replacement for the commonly used compound zinc pyrithione.
Zinc pyrithione is structurally similar to ciclopirox and pyrithione, containing a substituted pyridine (pyridinone) group which inhibits ergosterol synthesis.

Zinc pyrithione is a preservative that is also used in anti-dandruff shampoos for Zinc pyrithione anti-fungal functions.

Zinc pyrithione, also known as Piroctone olamine, was developed as a solution to the problem of seborrheic dermatitis, that is, dandruff, and has antibacterial, antimicrobial and antifungal properties that can help treat scalp psoriasis and acne.
The mentioned properties can destroy fungi, bacteria and microorganisms that can cause itchy complaints in the hair and scalp and cause the scalp to become flaky.

Zinc pyrithione has the potential to have antifungal effects to prevent or treat fungal infections.
Zinc pyrithione helps reduce inflammation in the skin.

Zinc pyrithione provides antioxidant effect by protecting the skin from the harmful effects of free radicals.
Zinc pyrithione shows cleansing potential to remove dirt, oil and debris.
Zinc pyrithione can help eliminate bad odors.

Zinc pyrithione is a wide spectrum antibacterial and antifungal agent used in the treatment of dandruff,fungal infections.
Zinc pyrithione works to treat dandruff at the root cause by functioning as a fungicide with specific efficacy against Malassezia.

Zinc pyrithione is a synthetic ingredient that is used mainly as a preservative in personal care and cosmetic products.
Shampoos with Zinc pyrithione are very effective in curing dandruff and preventing hair loss.

Zinc pyrithione (or Piroctone olamine) is a coordination complex of zinc.
Zinc pyrithione has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis[2] and dandruff.

Zinc pyrithione has anti-fungal properties and appears as a crystalline powder in Zinc pyrithione raw form that is white or slightly yellow in color.
Further, Zinc pyrithione is slightly soluble in oil and water.
The chemical formula of Zinc pyrithione is C14H23NO2.C2H7NO.

Zinc pyrithione has a petrochemical origin.
Zinc pyrithione is an ethanolamine salt extracted from hydroxamic acid derivative piroctone.
Typically, Zinc pyrithione is an alternative to the commonly used compound zinc pyrithione.

Almost everyone faces hair related issues like dandruff, hair loss, slow hair growth, and split ends.
Shampoos containing Zinc pyrithione are effective in treating various kinds of hair problems.

Zinc pyrithione is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and at the same time, provided hair conditioning advantages.
Recently was shown, that Zinc pyrithione could induce apoptosis and possessed a significant in vivo effect against myeloma.

Zinc pyrithione is a pyridone derivative, which is known to have bactericidal effects on gram-positive and gram-negative bacteria and fungicidal effects and hence is a component of many cosmetic products such as anti-dandruff shampoo.

Zinc pyrithione, also called Octopirox, is an antifungal of the hydroxy-pyridone family unrelated to other antiseptics used in veterinary medicine.
Members of the “pirox” family are currently used in the human field as topicals to cure onychomycosis and Malassezia-related skin disorders.

Zinc pyrithione has broad in vitro activity against major dermal veterinary pathogens, including dermatophytes and yeasts as well as some Gram positive (Staphylococcus) and Gram negative (Pseudomonas) bacteria.
As opposed to azole derivatives, PO remains fully active on resting fungal cells; Zinc pyrithione antiseptic activity proceeds from inhibition of the respiratory chain in yeast mitochondria.

No resistance to PO has been documented to date.
In addition, this antiseptic acts at low concentrations, has high affinity for keratin and is completely safe.
Incorporation of PO in Allermyl therefore aims at controlling microbial proliferation associated with allergic disease.

Zinc pyrithione is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Zinc pyrithione is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Zinc pyrithione is known for many years as a successor to Ketoconazole as an excellent anti-dandruff agent.
More recently Zinc pyrithione has been discovered that Zinc pyrithione has a much broader protection range against all kinds of microbiological species.

Is also being used in many preservative formulations at neutral pH, which is important for sunscreen formulations.

Zinc pyrithione is slightly soluble in both water and oil.
Freely soluble in 10% ethanol in water.

Soluble in solutions containing surfactants in water or in 1-10% ethanol.
The solubility of Zinc pyrithione in water varies by pH value.
This is a little larger in neutral or weak basic solutions than in acid solutions.

Typical use level is only 0.05 – 0.2%.

Zinc pyrithione is a hydroxamic acid that inhibits ergosterol synthesis, the main component of the cell wall of most fungi.
Zinc pyrithione is used as a cream or shampoo at a 0.5–1% concentration.

Zinc pyrithione alone or in combination with other agents has been demonstrated to reduce erythema, scaling, burning/stinging sensation, and pruritus in patients with FSD, with excellent cosmetic results.
Zinc pyrithione is an antidandruff agent used in antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action.

Designed specifically to treat seborrheic dermatitis and dry scalp, Zinc pyrithione offers additional benefits: Zinc pyrithione is environmentally friendly, multifunctional (doubles as preserving agent), and flexible for various cosmetic formats.
Zinc pyrithione is compatible with most surfactants, additives and active ingredients used in cosmetic formulations.

Zinc pyrithione is an effective, practically nontoxic antidandruff active ingredient.
Zinc pyrithione is particularly suitable for the manufacture of antidandruff shampoos and hair care products such as hair tonics and cream rinses with an antidandruff action.

Zinc pyrithione is a highly effective antidandruff agent and an anti-acne active agent.
Zinc pyrithione is antimicrobial, soluble in surfactant systems.
Zinc pyrithione is used shampoos, shower products, liquid soaps, hair conditioners, hair styling products, antiperspirant & deodorants.

Zinc pyrithione, despite the recent upsurge in usage, has historically not been a hugely popular ingredient.
So very few independent clinical studies have been performed.
Zinc pyrithione main advantage is that it’s well tolerated, and so can be used frequently to control mild dandruff, but this hasn’t been properly evaluated.

Zinc pyrithione is one of the more recent active ingredients found in dandruff shampoos.
Designed to treat seborrheic dermatitis and dry scalp Zinc pyrithione is one of the most innovative areas of dandruff treatment on the market today.

Dandruff and seborrheic dermatitis can cause hair loss and thinning hair.
Zinc pyrithione is assumed that dandruff and seborrheic dermatitis (dandruff is a form of seborrheic dermatitis) are caused by a yeast (single cell fungus) on the skin, the Malassezia globose.
This is a fungus that occurs only on the scalp.

Often times, the problem will not go away on Zinc pyrithione own and requires continues treatment.
A well-known agent for this is shampoo with Ketoconazole in high concentration.
Multiple studies about the effectiveness of Zinc pyrithione have shown that Zinc pyrithione stimulates hair growth and helps against hereditary hair loss.

Ketoconazole is most well-known, but Zinc pyrithione is not the only proven anti-dandruff ingredient in shampoos which stimulates hair growth.
Zinc pyrithione has a similar effect as Ketoconazole.

Zinc pyrithione is also listed under the brand name 'Octopirox'.
In a study with 150 men who suffer from hereditary hair loss and dandruff, Ketoconazole and Zinc pyrithione were compared.

Excessive secretion of sebum, dandruff and seborrheic dermatitis are often linked with hair loss and hereditary hair loss.
The 150 men received a shampoo with 1% Ketoconazole or 1% Zinc pyrithione.
They had to use this shampoo 2 to 3 times per week for a duration of six months.

All treatments showed a reduction in itching and dandruff after 2 to 6 weeks.

If we take a look at the effect of the treatments on various hair growth parameters, we see the following figures (in percentages):
The severity of hair loss decreases (Ketoconazole: -17.3%, Zinc pyrithione: -16.5%)

The percentage of hairs in the growth phase increases (Ketoconazole 4.9%, Zinc pyrithione: 7.9%)
The effect on the hair diameter is increased by 5.4% with Ketoconazole and by 7.7% with Zinc pyrithione.

Thus, the study shows that Zinc pyrithione scores better in a number of areas in comparison to Ketoconazole.

Compared to Ketoconazole, Zinc pyrithione ensures an increase in the number of hairs in the growth phase (anagen phase) by more than 10% in 33% of people.
Zinc pyrithione gives 88% of the people thicker hair, despite hereditary hair loss, whereby this is 78% with Ketoconazole.
If we take a look at how many people experience a significant increase (more than 10%) of the hair diameter, this is 28% with Ketoconazole and as much as 34% with Zinc pyrithione (10% larger diameter means that the hair became 20% heavier).

The above results show that both Ketoconazole and Zinc pyrithione have a positive effect on multiple aspects of hair growth.
They have a similar effect on itch and dandruff.
Zinc pyrithione generally scores better when Zinc pyrithione comes to hair growth.

Zinc pyrithione is a preservative also used for Zinc pyrithione antifungal functions in anti-dandruff shampoos.
Zinc pyrithione is forbidden in organic.

Restriction in Europe:
Maximum concentration in ready-to-use preparation

Maximum content of secondary amine: 0.5%

Other restrictions:
Do not use with nitrosating systems
Minimum purity: 99%
Maximum content of secondary amine: 0.5% (applies to raw materials)
Maximum nitrosamine content: 50 micrograms / kg
Keep in containers without nitrite

If used as a conservator:

The maximum concentration allowed in ready-to-use cosmetic preparations is:
1.0% in Zinc pyrithiones to be rinsed
0,5% in other products

Applications of Zinc pyrithione:
Zinc pyrithione is quite beneficial in maintaining cosmetic and personal care products.
Zinc pyrithione can commonly be found in products like shampoos, cleansers, and hair masks.

Skin care:
Zinc pyrithione can be used to eliminate the bad odor from the surface of the skin.
Zinc pyrithione is a great preservative that helps in keeping skin care products free from bacterial growth.

Hair care:
Zinc pyrithione is one of the most common 'anti-dandruff' ingredients that is added to hair care products.
Zinc pyrithione is also good for preventing hair loss and split ends.

Cosmetic products:
In cosmetic products, Zinc pyrithione makes use of Zinc pyrithione antifungal properties to keep Zinc pyrithiones free from unwanted bacterial growth for a longer time.
The addition of Zinc pyrithione improves the quality of Zinc pyrithiones and makes them last longer.

Uses of Zinc pyrithione:
Zinc pyrithione is a broad-spectrum microbiocide/microbiostat, may be used in formulating antidandruff shampoo, hair keep and hair care, soap, etc.

Zinc pyrithione is used in shampoo, hair care, bath liquid, cosmetics, skin care products and washing products.
Zinc pyrithione has a unique effect in relieving skin itching, with excellent anti-itch effect, can effectively kill fungi on the skin, and has a special effect in eliminating body odor.
Zinc pyrithione is a safe, non-toxic, non-stimulating, ideally effective fungicide.

Zinc pyrithione anti-dandruff and anti-itch effect is superior to similar products.
Excellent solubility and compound performance, no precipitation or stratification when mixed with cosmetic raw materials.
Unique anti-dandruff mechanism, very low irritation, no hair loss, no hair breakage, safety is better than similar anti-dandruff anti-itch products.

Medicine:
Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
Zinc pyrithione also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor and vitiligo.

Paint:
Because of its low solubility in water (8 ppm at neutral pH), zinc pyrithione is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc pyrithione is an algaecide.

Zinc pyrithione is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc pyrithione is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc pyrithione is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges:
Zinc pyrithione is an antibacterial treatment for household sponges, as used by the 3M Corporation.

Clothing:
A process to apply zinc pyrithione to cotton with washable results was patented in the United States in 1984.
Zinc pyrithione is used to prevent microbe growth in polyester.

Textiles with applied zinc pyrithione protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.

Suggested use:
One in every three persons suffers from a problem related to their hair.
Whether Zinc pyrithione is dandruff, loss of hair, slow growth of hair or split ends, the masses are struggling to find a solution to their hair problems.

And in this search for the solution, they often find themselves looking at different shampoos and conditioners to solve the problem.
The issue is that most people end up selecting famous shampoos and conditioners, which may not necessarily be the most effective ones.

The most effective are not usually the ones which are famous (as anything can become famous if Zinc pyrithione is marketed and advertised well), they are the ones that have the appropriate ingredients.
Zinc pyrithione is the answer to that question.

Rate of Application:
Antidandruff hair keep: 0.1-0.8% active ingredient.
Antidandruff fixing agent: 0.05-0.2% active ingredient.
Antidandruff hair emulsion: 0.1-0.3% active ingredient.
Antidandruff hair supporting: 0.05-0.1% active ingredient.
Preservative: 0.2-0.5% active ingredient
Smell-eliminating agent: 0.2-0.5% active ingredient
Smell-eliminating scented soap: 0.2-0.5% active ingredient.

Consumer Uses:
Zinc pyrithione is used in the following products: cosmetics and personal care products and perfumes and fragrances.
Other release to the environment of Zinc pyrithione is likely to occur from: indoor use as processing aid.

Widespread uses by professional workers:
Zinc pyrithione is used in the following products: cosmetics and personal care products.
Zinc pyrithione is used for the manufacture of: chemicals.
Other release to the environment of Zinc pyrithione is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

Uses at industrial sites:
Zinc pyrithione is used in the following products: cosmetics and personal care products and perfumes and fragrances.
Zinc pyrithione is used for the manufacture of: chemicals.
Release to the environment of Zinc pyrithione can occur from industrial use: in processing aids at industrial sites and in the production of articles.

Benefits of Zinc pyrithione:
Zinc pyrithione has been specially developed to solve dandruff problems.
Zinc pyrithione prevents the scalp from flaking.

Zinc pyrithione contributes to the purification of hair roots from bacteria and fungi.
Zinc pyrithione is effective in eliminating the factors that cause itching at the roots of the hair.
Zinc pyrithione helps purify and cleanse the hair and scalp.

Shampoos, which have Zinc pyrithione as one of their ingredients, are known to eliminate dandruff.
However, before we learn how they cure dandruff, we must know what causes dandruff in the first place.

Dandruff is caused due to fungal growth, excess sebum secretion and local inflammations.
Often all these together cause dandruff.

Moreover, when the scalp’s skin renewal process is impaired, the excess dead cells form clumps on the head and seem like visible flakes to the eye, which are termed as dandruff.
Excess sebum also acts as an ingredient for the growth of fungus on the scalp, which increases the acids on the scalp that cause irritation and itching.

This leads to local inflammation, which enhances the growth of cells leading to the formation of flakes that seem like dandruff on the scalp.
The reason why shampoos with Zinc pyrithione can reduce and eliminate dandruff is that Zinc pyrithione is known to kill the fungus or the fungal infections that irritate the scalp.

Moreover, Zinc pyrithione is also well known for reducing hair loss and promoting the growth of hair.
Due to these many benefits, Zinc pyrithione is considered a great ingredient in shampoos.

Cures Dandruff:
Malassezia Globosa is not a friendly fungus found in your scalp.
Zinc pyrithione is the main reason behind scalp issues like dandruff and seborrheic dermatitis.

Your scalp becomes irritated and starts shedding tiny flakes.
In severe cases, you will notice inflammation, redness, and extremely itchy patches.
If you want to prevent your scalp from worsening, it’s essential to control the situation promptly.

Zinc pyrithione has antifungal properties, which will help you control the spread of Malassezia globosa.
Use an anti-dandruff shampoo containing Zinc pyrithione to fight dandruff.

Prevents Hair Loss:
Regardless of your gender and age, you may face hair fall, mostly caused due to dirt, dust, pollution, dandruff, excessive use of hair styling tools, etc.
Dandruff makes your scalp itchy, which leads to constant scratching, redness, and hair follicle damage.

Even though hair fall due to dandruff is not a significant concern but in people with androgenic alopecia (a condition that leads to baldness), Zinc pyrithione is a proven cure for reducing hair fall.
As Zinc pyrithione effectively works on dandruff and fungal infections, naturally, your hair loss decreases over time.

Boosts Hair Growth:
Zinc pyrithione encourages hair growth in many ways.
Zinc pyrithione reduces hair fall and increases the hair diameter.
Zinc pyrithione is often compared to Ketoconazole, which is a widely used ingredient for dandruff, but Zinc pyrithione provides better results for dandruff and fungal infections.

Ketoconazole + Zinc pyrithione is a combination of two antifungal medicines:
Ketoconazole and Zinc pyrithione which treat dandruff.

Ketoconazole kills fungi by destroying the fungal cell membrane.
Zinc pyrithione works by penetrating the cell membrane of the fungi to interfere with their energy metabolism and oxygen uptake.
This kills the fungi and clears up the infection.

Functions of Zinc pyrithione:

Preservative:
Inhibits the development of microorganisms in cosmetic products.

Anti dandruff:
Helps fight against dandruff.
Zinc pyrithione is an active, dandruff-fighting ingredient used in some of our shampoos.

Characteristics of Zinc pyrithione:
Zinc pyrithione is known for its bacteriostatic and fungistatic properties specifically working against Pityrosporum ovale, which lives on the skin and is associated with dandruff and other manifestations of flaking on the face and scalp.
Zinc pyrithione also reduced sebum production.

Appearance of Zinc pyrithione:
Zinc pyrithione has a white crystalline powder structure.

Resolution of Zinc pyrithione:
Zinc pyrithione has low solubility in water.
Zinc pyrithione dissolves better in some organic compounds.

Structure of Zinc pyrithione:
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer, where each zinc is bonded to two sulfur and three oxygen centers.
In solution, however, the dimers dissociate via scission of one Zn-O bond.

This compound was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.

Solubility of Zinc pyrithione:
The solubility of Zinc pyrithione is greatly dependent on the pH.
Generally speaking, Zinc pyrithione solubility in aqueous formulations is greater in the neutral and weakly alkaline ranges than in the acid range (formation of free acid).
Zinc pyrithione does however have adequate solubility in the usual pH range (pH5 - 8) in commercial surfactant solutions and alcohol-water mixtures.

Extraction method of Zinc pyrithione:
Zinc pyrithione is a particular salt that is also known as Octopirox and Piroctone ethanolamine.
Zinc pyrithione is a compound, which is often used to cure fungal infections.
Zinc pyrithione is a hydroxamic acid derivative Piroctone.

Action Mechanism of Zinc pyrithione:
Zinc pyrithione antifungal effect is thought to derive from Zinc pyrithione ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.

Origin of Zinc pyrithione:
Zinc pyrithione is of petrochemical origin and helps treat dandruff.
There is no natural alternative that comes close to being as effective as this.

History of Zinc pyrithione:
Zinc pyrithione has been used for around 40 years, first developed by Schwarzkopf-Henkel for use in anti-dandruff shampoo in the late 1970s.
All the initial clinical and safety studies were conducted by Hoechst AG, but this changed in the mid-1990s when other cosmetics companies began using the ingredient.

Zinc pyrithione was first submitted for approval to the European Union and United States FDA in the 1980s.
The ingredient was first approved for addition to the United States Pharmacopeia (USP) in 2008, after the FDA sought additional safety and effectiveness data in 2004.

Health effects of Zinc pyrithione:
Zinc pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several anti-dandruff shampoos and body wash gels.
In Zinc pyrithione industrial forms and strengths, Zinc pyrithione may be harmful by contact or ingestion.
Zinc pyrithione can in the laboratory setting trigger a variety of responses, such as DNA damage in skin cells.

Legal status of Zinc pyrithione:
Use of zinc pyrithione is prohibited in the European Union since December 2021.
Zinc pyrithione was considered safe for use in rinse-off and leave-in products of different tested concentrations, but due to environmental toxicity standard regulation was considered against potential alternatives – and as no submission was made for its use Zinc pyrithione was automatically prohibited.

Environmental concerns of Zinc pyrithione:
A large Swedish study shows that Zinc pyrithione is broken down in wastewater plants and does not release into waterways.
A Danish study shows that Zinc pyrithione biodegrades quickly, but that a risk of continuous leaching from boat paint may cause environmental toxicity.

Handling and storage of Zinc pyrithione:

Advice on safe handling:
Avoid contact with skin and eyes.
Avoid formation of dust and aerosols.

Advice on protection against fire and explosion:
Provide appropriate exhaust ventilation at places where dust is formed.

Hygiene measures:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.

Storage stability:

Recommended storage temperature: 2 - 8 °C

Storage class:
Storage class (TRGS 510): 13: Non Combustible Solids

Stability and reactivity of Zinc pyrithione:

Reactivity:
No data available

Chemical stability:
Stable under recommended storage conditions.

Possibility of hazardous reactions:
No data available

Conditions to avoid:
No data available

Incompatible materials:
Strong acids and oxidizing agents, Strong oxidizing agents

Health Effect of Zinc pyrithione:
If used as a preservative, Zinc pyrithione should be used at a maximum rate of 1.0% in rinsed products and at a maximum rate of 0.5% in other products.
Zinc pyrithione should not be used together with nitrosamine-forming agents.

Nitrosamines are carcinogenic substances.
The impurity rate should be 99%.

The maximum amount of secondary amine should be 0.5%.
The maximum amount of nitrosamine cannot exceed 50 micrograms/kg. The raw material should be stored in nitrite-free packaging.

Zinc pyrithione is a synthetic component.
They are raw materials produced using various processes under laboratory conditions.

These are raw materials obtained without using animal sources (propolis, honey, beeswax, lanolin, collagen, snail extract, milk, etc.).
Zinc pyrithione is a criterion that should be taken into consideration for those who want to use vegan products.

Studies have concluded that different effects can be seen on each skin type.
For this reason, the allergy/irritation effect may vary from person to person.
However, Zinc pyrithione causes stinging, tingling, itching, redness and irritation, especially in people with sensitive skin types.

Precaution of Zinc pyrithione:
However, just like excess of anything is bad, too much of Zinc pyrithione can be bad for the scalp too.
This is precisely why shampoos with Zinc pyrithione have a very minor amount of Zinc pyrithione so that its side effects do not affect the scalp in any way.

Zinc pyrithione should be kept in mind that shampoos with Zinc pyrithione should not be used more than twice a week, unlike other daily use shampoos that don’t have this ingredient.
One of the biggest side effects of Zinc pyrithione is that Zinc pyrithione can cause irritation and itchiness on the head.

First aid measures of Zinc pyrithione:

General advice:
Consult a physician.

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.

In case of skin contact:
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures of Zinc pyrithione:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from Zinc pyrithione:
Carbon oxides
Nitrogen oxides (NOx)

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.

Further information:
No data available

Accidental release measures of Zinc pyrithione:

Personal precautions, protective equipment and emergency procedures:
Use personal protective equipment.
Avoid dust formation.

Avoid breathing vapors, mist orgas.
Ensure adequate ventilation.

Evacuate personnel to safe areas.
Avoid breathing dust.

Environmental precautions of Zinc pyrithione:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Pick up and arrange disposal without creating dust.
Sweep up and shovel.
Keep in suitable, closed containers for disposal.

Identifiers of Zinc pyrithione:
CAS Number: 68890-66-4
ChemSpider: 45574
ECHA InfoCard: 100.065.957
MeSH: Piroctone+olamine
PubChem CID: 50258
UNII: A4V5C6R9FB
CompTox Dashboard (EPA): DTXSID4046735
InChI: InChI=1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
Key: BTSZTGGZJQFALU-UHFFFAOYSA-N
InChI=1/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
Key: BTSZTGGZJQFALU-UHFFFAOYAP
SMILES: CC1=CC(=O)N(C(=C1)CC(C)CC(C)(C)C)O.C(CO)N

CAS NO: 68890-66-4
EC NO: 272-574-2

Synonym(s): 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1H)-pyridone ethanolammonium salt
Empirical Formula (Hill Notation): C14H23NO2 · C2H7NO
CAS Number: 68890-66-4
Molecular Weight: 298.42
EC Number: 272-574-2
MDL number: MFCD01690792
PubChem Substance ID: 329757760
NACRES: NA.24

Product Number: P2178
Purity / Analysis Method: >97.0%(T)(HPLC)
Molecular Formula / Molecular Weight: C14H23NO2·C2H7NO = 298.43
Physical State (20 deg.C): Solid
Storage Temperature: 0-10°C
Condition to Avoid: Heat Sensitive
CAS No: 68890-66-4
Related CAS No: 50650-76-5
Reaxys Registry Number: 7503297
PubChem Substance ID: 253662076
Merck Index (14): 7502
MDL Number: MFCD01690792

Properties of Zinc pyrithione:
Chemical formula: C16H30N2O3
Molar mass: 298.421

Molecular weight: 298.43
Formula: C14H23NO2·C2H7NO
Purity: >97.0%(T)(HPLC)
Color/Form: White to Almost white powder to crystal
MDL: MFCD01690792
Melting point: 136 °C
Flash point: 136 °C
HS code: 2933790090

grade: analytical standard
Quality Level: 100
Assay: ≥99.0% (HPLC)
shelf life: limited shelf life, expiry date on the label

technique(s)
HPLC: suitable
gas chromatography (GC): suitable

application(s):
agriculture
environmental

format: neat
storage temp.: 2-8°C
SMILES string: NCCO.CC(CC1=CC(C)=CC(=O)N1O)CC(C)(C)C
InChI: 1S/C14H23NO2.C2H7NO/c1-10-6-12(15(17)13(16)8-10)7-11(2)9-14(3,4)5;3-1-2-4/h6,8,11,17H,7,9H2,1-5H3;4H,1-3H2
InChI key: BTSZTGGZJQFALU-UHFFFAOYSA-N

Molecular Weight: 298.42 g/mol
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 5
Exact Mass: 298.22564282 g/mol
Monoisotopic Mass: 298.22564282 g/mol
Topological Polar Surface Area: 86.8Ų
Heavy Atom Count: 21
Complexity: 371
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 2
Compound Is Canonicalized: Yes

Specification of Zinc pyrithione:
Appearance: White or slightly yellow crystalline powder
Odor: Characteristic

Solubility:
Water (0.10g +10ml):non-soluble
Methanol (1.00g + 10ml): soluble

Purity(HPLC) %: ≥99.0
PH value(1% aqueous suspension,20℃): 8.5-10.0
Melting Point ℃: 130-135
Drying loss %: ≤0.3
Ash(SO4) %: ≤0.2
Particle size distribution: D(0.5): 30-50um Provide a profile representative of the raw material
E1% (1cm) at 317 nm expressed an dried substance: 214-236
Ethanolamine %: 20.0-21.0
Nitrosamine content PPB: ≤50
Heavy metals(Pb,As,Cd,Co,Cr,Hg,Ni,Sb) PPM: ≤10
Hexane(GC) PPM: ≤300
Ethyl acetate(GC) PPM: ≤5000

Names of Zinc pyrithione:

Regulatory process names:
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl) 2-pyridon, monoethanolamine salt
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
2(1H)-Pyridinone, 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-, compd. with 2-aminoethanol (1:1)
Kopirox
Octopirox
Piroctone ethanolamine salt
Piroctone olamine
Bio Boost 2300EX
Blo Boost 2300EX
Pyrithione zinc
Pyrithione zinc
pyrithione zinc
Pyrithione zinc (Zinc pyrithione)
pyrithione zinc; (T-4)-bis[1-(hydroxy-κO)pyridine-2(1H)-thionato-κS]zinc
Zinc pyrithione
Zinc Pyrithlone
Zink Pyrithione (zinc omadine)

IUPAC names:
(RS)-1-HYDROXY-4-METHYL-6-(2,4,4-TRIMETHYLPENTYL)-2(1H)-PYRIDINONE ETHANOLAMINE (1:1)
1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine salt
1-hydroxy-4-methyl-6-(2,4,4-trimethylpently)pyridin-2-(1H)-one compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-1,2-dihydropyridin-2-one; 2-aminoethan-1-ol
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-(1H)pyridinone, 2-aminoethanol salt
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one - 2-aminoethanol (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2(1H)-one,compound with 2-aminoethanol (1:1)
1-hydroxy-4methyl-6-(2,4,4-trimethylphenyl)pyridine-2(1H)-one, compound with 2-aminoethanol(1:1)
2-aminoethanol; 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
2-aminoethanol;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)pyridin-2-one
2-amminoetanolo; 1-idrossi-4-metil-6-(2,4,4-trimethylpentyl) pyridin-2-one
Octopirox
Piroctone Olamine
Piroctone Olamine
Piroctone olamine
1-oxidopyridine-6-thiolate, zinc (II) cation
2-Mercaptopyridine N-Oxide Zinc Salt
Bis [1-hydroxy-2(1H)-pyridinethionato-O,S](T-4)-zinc
bis(1-hydroxy-2(1h)-pyridinethionato)zinc
bis(1-hydroxy-2(1H)-pyridinethionato-O,S)-(T-4) zinc
Bis(1-hydroxy-2(1H)-pyridinthionato-O,S) zinc
bis(2-pyridylthio)zinc 1,1'-dioxide
bis[1-hydroxy-2-(1H)-pyridine-thionato]zinc
Kopthione Zn
Mercaptopyridine N-oxide zinc salt, Pyrithione
Mercaptopyridine N-oxidezinc salt
Pyrithione zinc
pyrithione zinc
pyrithione zinc`
Zinc 1-oxidopyridin-1-ium-2-thiolate
zinc 1-oxidopyridin-1-ium-2-thiolate
Zinc 2-pyridinethiol-1-oxide
zinc bis(2-thioxopyridin-1(2H) -olate)
zinc bis(2-thioxopyridin-1(2H)-olate)
Zinc pyridinethione
Zinc pyrithion
Zinc Pyrithione
Zinc pyrithione
zinc(2+) bis(2-sulfanylidene-1,2-dihydropyridin-1-olate)
ZINC, BIS(1-HYDROXY-2(1H)-PYRIDINETHIONATO)- (6CI,7CI,8CI)
zinc;1-oxidopyridin-1-ium-2-thiolate

Translated names:
Cinko piritionas (lt)
Piirition taż-żingu (Piirition taż-żingu) (mt)
Pirition cink (cinkov pirition) (hr)
Pirition cink (cinkov pirition) (sl)
Pirition-cink (Cink-pirition) (hu)
Piritiona de cinc (es)
Piritiona-zinco (piritiona de zinco) (pt)
Piritioncinks (cinka piritions) (lv)
Piritionă de zinc (ro)
Pirytionian cynku (pl)
Pyrithion-Zink (Zink-Pyrithion) (de)
Pyrithione zinc (Zinc pyrithione) (no)
Pyrithione zincique (pyrithione de zinc) (fr)
pyrithionzink (da)
Pyrithionzink (zinkpyrithion) (nl)
Pyritionisinkki (sinkkipyritioni) (fi)
Tsinkpüritioon (et)
Zinco piritione (piritione zincica) (it)
zink-1-oxo-1λ5-pyridin-2-thiolát (cs)
zinkium-pyritión (sk)
Zinkpyrition (Pyritionzink) (sv)
Άλας πυριθειόνης με ψευδάργυρο (Zinc pyrithione) (el)
Цинков пиритион (bg)
Picroctone Olamine
Piroctone olamine

Other identifiers:
1021487-49-9
109702-19-4
118480-78-7
1192-70-7
1199553-62-2
1320-68-9
1323439-04-8
13463-41-7
14376-32-0
15686-64-3
162400-43-3
16782-00-6
17652-47-0
186322-74-7
192458-89-2
208398-70-3
226883-65-4
244778-79-8
266692-38-0
31089-48-2
3138-01-0
318995-78-7
35430-20-7
3590-23-6
3865-77-8
39412-61-8
51148-10-8
51406-57-6
55172-61-7
613-333-00-7
74261-71-5
943428-71-5
68890-66-4
ZINC PYRITHIONE (ANTIDANDRUFF)
Zinc Pyrithione (Antidandruff) is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chem/IUPAC Name: Pyridine-2-thiol-1-oxide, zinc complex (2:1)
Chemical formula: C10H8N2O2S2Zn



SYNONYMS:
Zinc pyrethion, Zinc pyridine-2-thiol 1-oxide, Zinc pyridinethione, Zinc-pyrion, Zinc pyrithione, Zinc pyrithione, Zinc 1-hydroxy-2-pyridinethione, Zinc 2-mercaptopyridine N-oxide, Zinc Omadine, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, Zinc, bis(2-pyridinylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, N,N'-dioxide, Zinc, bis(2-pyridylthio)-, 1,1′-dioxide, Zincpolyanemine, Zn – pyrion, ZnPT, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc Pyrithione, 48% Aqueous Dispersion, Zinc Pyrithione 48% Aqueous Dispersion, Zinc Pyritione 48%, Zinc Pyrithione, T/N: Zinc Omadine 48% FPS, Zinc Pyridinethione, Zinc Omadine, Pyrithione Zinc, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, bis(2-pyridylthio)zinc 1,1'-dioxide, ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT, Zinc pyrithione, OM-1563, Zinc pyridine thioneone, de-squaman, N-HYDROXYPYRIDINETHIONE ZINC SALT, zincpolyanemine, bis(1-hydroxy-2-(1h)-pyridinethionato) zinc, Zinc pyrithione, OM-1563, DTXSID7026314, DTXCID90820451, Bis((1-oxidopyridin-2-yl)thio)zinc, zinc;1-oxidopyridin-1-ium-2-thiolate, NCGC00091933-01, NCGC00183121-01, Zinc pt, Zinci pyrithionum, Finecide ZPT, Hokucide ZPT, Niccanon SKT, Biocut ZP, zinc bis(2-thioxopyridin-1(2H)-olate), 1698050-37-1, Tomicide Z 50, Tomicide ZPT 50, CAS-13463-41-7, Evafine P 50, Caswell No. 923, Zinc Pyrithione Powder, BC-J, Zincopan, Zolidyne, pyrthione zinc, DermaZinc, Zinc 2-pyridinethiol-1-oxide, Zinc-pyrion, Zn-pyrion, Pyrithizone Zinc, Zinc pyridine-2-thiol 1-oxide, Zinc 1-hydroxy-2-pyridinethione, Zinc bis(2-pyridylthio)-N-oxide, Bis(2-pyridinethiol-1-oxide)zinc, pyrithione (base), Piritionato cincico, Pyrithione zincique, FSB 8332, 2-Pyridinethiol-1-oxide, zinc salt, Pyrithione Zinc 1%, Bis(2-pyridylthio)zinc 1,1'-dioxide, NSC 290409, bis(N-oxopyridine-2-thionato)zinc (II), AI3-62421, Zinc, bis(1-hydroxy-2(1H)-pyridinethionato)-, UNII-R953O2RHZ5, (T-4)-Bis(1-hydroxy-2(1H)-pyridinethionato-O,S)zinc, D11AX12, bis(1-oxidopyridin-2-ylthio)zinc, BDBM429354, Tox21_111182, Tox21_113399, Tox21_202180, Tox21_303205, MFCD00067336, AKOS040732194, OM 1563, ZINC PYRIDINE-2-THIONE-N-OXIDE, NCGC00257089-01, NCGC00259729-01, 1ST10354, 2-PYRIDINETHIOL N-OXIDE ZINC SALT, BIS(2-PYRIDINETHIOL 1-OXIDE)ZINC, ZINC 1-HYDROXY-2-PYRIDINE-THIONE, Bis(1-hydroxy-2-(1H)-pyridinethionato)zinc, 1-HYDROXY-2-PYRIDINETHIONE, ZINC SALT, BIS(2-PYRIDYLTHIO)ZINC, N,N'-DIOXIDE, BIS(2-PYRIDYLTHIO)ZINC, 1,1'-DIOXIDE, EC 236-671-3, F16428, Q-201649, 3590-23-6, 2(1H)-Pyridinethione, 1-hydroxy-, zinc complex, 2-Mercaptopyridine 1-oxide zinc salt, 2-Pyridinethiol-1-oxide, zinc salt, AI3-62421, BC-J, Biocut ZP, Bis(1-hydroxy-2(1H)-pyridinethionato)zinc, Bis(2-pyridinethiol-1-oxide)zinc, Bis(2-pyridylthio)zinc 1,1′-dioxide, CCRIS 4894, Caswell No. 923, EINECS 236-671-3, EPA Pesticide Chemical Code 088002, Evafine P 50, FSB 8332, Finecide ZPT, HSDB 4498, Hokucide ZPT, NSC 290409, Niccanon SKT, OM-1563, Omadine Zinc, Tomicide Z 50, Tomicide ZPT 50, Top Brass, Vancide P, Vancide ZP, ZNP Bar, ZPT, Zinc PT,



Zinc Pyrithione (Antidandruff) is a chemical compound consiting of zinc and pyrithione.
Zinc Pyrithione (Antidandruff) is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.


Zinc Pyrithione (Antidandruff) can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Pyrithione (Antidandruff) or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.


In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione (Antidandruff) is used to treat dandruff and seborrheic dermatitis.
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.


Zinc Pyrithione (Antidandruff) is one of the most popular anti-dandruff ingredients contributing bactericide-fungicide action in shampoos, conditioners, and leave-on products.
Zinc Pyrithione (Antidandruff) is a dispersion of fine particles that enhances the anti-dandruff efficacy and cosmetic performance attributes.


Zinc Pyrithione (Antidandruff) effectively fights against Malassezia spp. yeast, which is the primary factor in the development of dandruff on the scalp.
Malassezia is a lipid-loving organism and is therefore attracted to the lipophilically coated Zinc Pyrithione (Antidandruff), offering enhanced efficacy of the it, as well as counteracting some negative effects of shampooing such as dry scalp and residue build up on the hair.


Zinc Pyrithione (Antidandruff) (also called pyrithione zinc or ZPT) is known as a “coordination complex” of zinc and pyrithione.
Zinc Pyrithione (Antidandruff) offers bactericide-fungicide efficacy.
Zinc Pyrithione (Antidandruff) is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.


Zinc Pyrithione (Antidandruff) acts as an anti-dandruff and odor-controlling agent.
Zinc Pyrithione (Antidandruff), also known as Pyrithione Zinc, is an antibacterial, antimicrobial, and antifungal agent that can be used to treat dandruff, scalp psoriasis, and acne.


Zinc Pyrithione (Antidandruff) is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (Antidandruff) is known for its ability to fight dandruff and promote a healthy scalp.


Zinc Pyrithione (Antidandruff) is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc Pyrithione (Antidandruff) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.


Due to low solubility, Zinc Pyrithione (Antidandruff) released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.
Zinc Pyrithione (Antidandruff) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.


Zinc Pyrithione (Antidandruff) has the ability to inhibit the growth of yeast, which is a major cause of dandruff.
If you're struggling with dandruff or other scalp issues, look for hair care products containing Zinc Pyrithione (Antidandruff) to help alleviate your symptoms and promote a healthy scalp.


So while it does draw from the naturally occurring metal, Zinc Pyrithione (Antidandruff) is ultimately produced in a lab.
Zinc Pyrithione (Antidandruff) is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Pyrithione (Antidandruff) can effectively prevent precipitation and double the antimicrobial effect.


Zinc Pyrithione (Antidandruff), also commonly known as pyrithione zinc is derived from the chemical zinc, has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Pyrithione (Antidandruff) can inhibit the growth of yeast, which is a main factor in dandruff.


Zinc Pyrithione (Antidandruff) offers bactericide-fungicide efficacy.
Zinc Pyrithione (Antidandruff) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione (Antidandruff) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.


Zinc Pyrithione (Antidandruff) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Zinc Pyrithione (Antidandruff) is known for its ability to fight dandruff and promote a healthy scalp.


This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.
Zinc Pyrithione (Antidandruff) is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and
bacterial (gram-positive & gram-negative).


Zinc Pyrithione (Antidandruff) is a fungistatic and baceriostatic compound that has a variety of uses.
Zinc Pyrithione (Antidandruff) is a chemical compound derived from the natural element Zinc.
Zinc Pyrithione (Antidandruff) was first developed in the 1930s, then synthesized by E. Shaw in 1950.


For instance, Zinc Pyrithione (Antidandruff)’s an essential element in kitchen sponges, preventing the growth of mould.
Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (Antidandruff) is known for its ability to fight dandruff and promote a healthy scalp.


Zinc Pyrithione (Antidandruff) is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (Antidandruff) inhibits the growth of a broad spectrum of both Gram-positive and Gram-negative bacteria.


In the crystalline state, Zinc Pyrithione (Antidandruff) exists as a centrosymmetric dimer.
Zinc Pyrithione (Antidandruff) also inhibits the growth of fungi, yeast, mold, and algae.
Zinc Pyrithione (Antidandruff) is a mixture of ultra-fine particles of zinc pyrithione (ZPT), a dispersant and a stabilizing agent.



USES and APPLICATIONS of ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) has antibacterial, antimicrobial, and antifungal properties, which is why it’s often used in dandruff shampoo.
Other uses of Zinc Pyrithione (Antidandruff) include additive in antifouling outdoor paints and algaecide.
While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione (Antidandruff) has been reported for decades.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione (Antidandruff) works by targeting both local fungi and bacteria residing on the scalp.
Zinc Pyrithione (Antidandruff) can inhibit the growth of yeast, which is a main factor in dandruff.


As the name suggests, Zinc Pyrithione (Antidandruff) is derived from the chemical element zinc, and it’s used in a variety of hair and skin care products.
Zinc Pyrithione (Antidandruff) is a common ingredient in antidandruff shampoos, but it can also be effective at treating psoriasis, eczema, and acne.
This is because of Zinc Pyrithione (Antidandruff)'s antimicrobial, antibacterial, and antifungal properties.


Zinc Pyrithione (Antidandruff)’s used as an ingredient in skin care and hair products because of its antibacterial, antifungal and antimicrobial properties.
Zinc Pyrithione (Antidandruff) is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione (Antidandruff) is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.


In addition, an important characteristic of this molecule is that Zinc Pyrithione (Antidandruff) is efficacious against various bacteria species associated with producing odor on the skin.
Zinc Pyrithione (Antidandruff) is a fungistatic and bacteriostatic compound that has a variety of uses.


Zinc Pyrithione (Antidandruff) is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione (Antidandruff) is widely used as a fungicide for paints and plastics.
Zinc Pyrithione (Antidandruff) has unique advantages in environmental friendliness and sterilization persistence.


Zinc Pyrithione (Antidandruff) is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).
Zinc Pyrithione (Antidandruff) is also often used in kitchen sponges as an antibacterial treatment.


Zinc Pyrithione (Antidandruff) has been used topically for inflammatory skin conditions for more than 50 years.
Zinc Pyrithione (Antidandruff) has become one of the most common ingredients for improving issues like dandruff and seborrheic dermatitis.
Zinc Pyrithione (Antidandruff) can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.


As the name suggests, Zinc Pyrithione (Antidandruff) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.
Pharmaceutical Applications of Zinc Pyrithione (Antidandruff): Zinc Pyrithione (Antidandruff) is a regulator of keratinization, has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).


Zinc Pyrithione (Antidandruff) is used as a bactericide for coatings and plastics, etc.
Zinc Pyrithione (Antidandruff) is used in shampoos to remove dandruff, and can inhibit the growth of Gram-positive and negative bacteria and molds.
Zinc Pyrithione (Antidandruff) can effectively care for the hair, delay the aging of the hair, and control the generation of gray hair and hair loss.


Today, Zinc Pyrithione (Antidandruff)’s added to a range of skin and hair products, including shampoos, face washes and creams.
As the name implies, Zinc Pyrithione (Antidandruff) is generated from the chemical element zinc and is utilized in several haircare and skincare products.
Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione (Antidandruff) is suitable for outdoor coatings and other products that protect against mold and algae.


Look at the ingredient list of any product made to fight fungal or bacterial infections that affect the skin and you’re sure to see Zinc Pyrithione (Antidandruff).
Zinc Pyrithione (Antidandruff) is used in a variety of hair and skin care products.


In addition, Zinc Pyrithione (Antidandruff) is an effective algaecide.
Zinc Pyrithione (Antidandruff) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
Zinc Pyrithione (Antidandruff) acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.


Zinc Pyrithione (Antidandruff) can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.


As an anti-mildew agent, Zinc Pyrithione (Antidandruff) also has some applications on fabrics.
Therefore, Zinc Pyrithione (Antidandruff) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


Zinc Pyrithione (Antidandruff)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.
For shampoo to remove dandruff, Zinc Pyrithione (Antidandruff) can inhibit the growth of gram-positive and negative bacteria and mold.


Therefore, Zinc Pyrithione (Antidandruff) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Zinc Pyrithione (Antidandruff) has a strong killing effect on fungi and bacteria, can effectively kill the fungus that produces dandruff, and has an anti-dandruff effect.


Zinc Pyrithione (Antidandruff) is used in skincare, shampoos, conditioners and leave-on products.
Zinc Pyrithione (Antidandruff) is an antifungal, antibacterial, and antimicrobial agent for an anti-dandruff shampoo.
Zinc Pyrithione (Antidandruff) is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione (Antidandruff) is used to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione (Antidandruff) is a highly effective bactericide-fungicide, the anti-dandruff agent establishes the market standard for any active ingredient solutions in anti-dandruff shampoos.


Zinc Pyrithione (Antidandruff)'s high antimicrobial efficacy combined with the acceptability for human use has made it the agent of choice for anti-dandruff shampoo manufacturers worldwide.
Study shows that using a medicated soap that contains 2% may help clear acne, making Zinc Pyrithione (Antidandruff) a great active for black soap, cold or hot process soap.


Zinc Pyrithione (Antidandruff) anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione (Antidandruff) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.


Zinc Pyrithione (Antidandruff) has strong killing power on fungi and bacteria, can effectively kill the fungi that produce dandruff, and play an anti-dandruff effect.
Zinc Pyrithione (Antidandruff), as an anti-dandruff agent with a long history, is widely known in the shampoo industry and used by many well-known brands.


-Zinc Pyrithione (Antidandruff) is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc Pyrithione (Antidandruff) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth

1. Due to low solubility, Zinc Pyrithione (Antidandruff) released from the topical formulations is deposited and retained relatively well onto the target skin surfaces

2. Other uses of Zinc Pyrithione (Antidandruff) include additive in antifouling outdoor paints and algaecide.
While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione (Antidandruff) has been reported for decades.
Zinc Pyrithione (Antidandruff) is not shown to have any significant estrogenic activity according to the in vivo and in vitro assays


-Zinc Pyrithione (Antidandruff) is used in cream:
Seborrheic dermatitis often affects the scalp, but it can also cause rough, scaly patches on the skin.
Zinc Pyrithione (Antidandruff) is used to treat seborrheic dermatitis or psoriasis on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2% Zinc Pyrithione (Antidandruff) followed by a moisturizer.
You can also use Zinc Pyrithione (Antidandruff) daily by applying it in a thin layer to the affected area.


-Zinc Pyrithione (Antidandruff) is used face wash:
Zinc Pyrithione (Antidandruff) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione (Antidandruff) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2% Zinc Pyrithione (Antidandruff) may help clear acne.


-Zinc Pyrithione (Antidandruff) is used inshampoo:
Zinc Pyrithione (Antidandruff) shampoo is found in many common antidandruff shampoos.
Zinc Pyrithione (Antidandruff)’s antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.



HOW TO USE ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) is easily found in many drugstore and supermarket shampoo products.
There are also leave-in treatments available from retail haircare lines.

-Use in an anti-dandruff shampoo:
Zinc Pyrithione (Antidandruff) is most often found in anti-dandruff shampoos.
For best results, you should wet your hair and massage the shampoo into your scalp.

Let Zinc Pyrithione (Antidandruff) sit for approximately one minute (or as instructed on the shampoo label) before shampooing the rest of your hair and then rinse out.
Usage will depend on the sensitivity and state of your scalp.

While many shampoos containing Zinc Pyrithione (Antidandruff) can be used daily, I typically recommend using it at least two to three times per week.
For some individuals dealing with seborrheic dermatitis or dandruff, I often recommend washing the scalp daily or every other day to help eliminate the build-up of oils or dead skin, which may contribute to scaling or flaking.

If someone is concerned about dryness of the scalp, it is okay to use a Zinc Pyrithione (Antidandruff) shampoo a few days per week and a non-medicated shampoo on the alternating days.


-Use Zinc Pyrithione (Antidandruff) in a hydrating conditioner:
Conditioners with Zinc Pyrithione (Antidandruff) can help fight dandruff, itch, and flaking while restoring scalp balance and providing hydration.
After shampooing, massage the conditioner into your scalp and hair and cover it with a shower cap.

Leave on for 3 minutes and wash out.
Follow the instructions on the label for the best results.


-Relieve itch and flakes with a serum:
Serums with Zinc Pyrithione (Antidandruff) are great for those with oily scalps or severe flaking and dandruff.
Apply Zinc Pyrithione (Antidandruff) to the scalp in between washes to help with itch and flakes.
Follow the directions on Zinc Pyrithione (Antidandruff), but most can be applied several times a day.


-Apply Zinc Pyrithione (Antidandruff) in a scalp-soothing leave-in cream:
If your scalp tends to get dry, a leave-in cream is often more soothing and moisturizing than a serum.
The creams are often infused with hydrating products like vitamin E and argan oil to protect and moisturize, while the Zinc Pyrithione (Antidandruff) relieves dandruff, itch, and irritation.



ADVANTAGES OF ZINC PYRITHIONE (ANTIDANDRUFF):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Zinc Pyrithione (Antidandruff) helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Zinc Pyrithione (Antidandruff) is used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



INCLUDES ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) is found in several skin and hair products, including the following:

*Zinc Pyrithione (Antidandruff) shampoo:
Shampoos containing Zinc Pyrithione (Antidandruff) is used for the ingredient’s anti-dandruff properties.
Zinc Pyrithione (Antidandruff) helps kill fungus or bacteria that causes red, itchy and flaky scalp.

*Zinc Pyrithione (Antidandruff) face wash:
Because of its antimicrobial properties, Zinc Pyrithione (Antidandruff) face wash helps improve acne and relieve symptoms of skin issues, such as eczema, seborrheic dermatitis and psoriasis.

*Zinc Pyrithione (Antidandruff) soap:
Like face washes, body soaps medicated with Zinc Pyrithione (Antidandruff) have antifungal, antibacterial and antimicrobial effects.
Skin conditions like seborrheic dermatitis affect areas of the body beyond the face, like the upper chest, back, neck and groin.
For these issues and others caused by inflammation, Zinc Pyrithione (Antidandruff) soap may be helpful.

*Zinc Pyrithione (Antidandruff) cream:
For rough patches on the skin or dry skin caused by conditions like psoriasis, Zinc Pyrithione (Antidandruff) cream can be used for its moisturizing effects.



TYPE OF INGREDIENT OF ZINC PYRITHIONE (ANTIDANDRUFF):
Antifungal, antimicrobial, and antibacterial properties


MAIN BENEFITS OF ZINC PYRITHIONE (ANTIDANDRUFF):
Treats dandruff, soothes scalp irritation, regulates oil production, and prevents itching.


WHO SHOULD USE ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) is best for those experiencing dandruff or seborrheic dermatitis, which may be associated with an oily scalp.
It is best to consult a dermatologist to determine the cause of your scalp flakes or irritation before using Zinc Pyrithione (Antidandruff).


HOW OFTEN CAN YOU USE ZINC PYRITHIONE (ANTIDANDRUFF):
Shampoos containing Zinc Pyrithione (Antidandruff) can be used daily, and those individuals dealing with seborrheic dermatitis or dandruff are often advised to cleanse daily.
If the scalp is dry, it is okay to use a Zinc Pyrithione (Antidandruff) shampoo two to three days per week and a non-medicated shampoo on alternating days.


ZINC PYRITHIONE (ANTIDANDRUFF) WORKS WELL WITH:
Selenium sulfide, another ingredient commonly found in dandruff shampoos stronger than Zinc Pyrithione (Antidandruff).
Additionally, some individuals may alternate with other anti-dandruff ingredients, such as ketoconazole, an antifungal ingredient.


DON’T USE WITH ZINC PYRITHIONE (ANTIDANDRUFF):
There are no known ingredients that negatively interfere with Zinc Pyrithione (Antidandruff); however, it is advised that you speak to a medical professional before using if you are pregnant or nursing.



BENEFITS/USES OF ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff) can be used daily as an ingredient in an over-the-counter or prescription product.
If it causes dryness to the scalp or skin, rotate using the Zinc Pyrithione (Antidandruff) product with a non-medicated product.
The top benefits and uses of Zinc Pyrithione (Antidandruff) include:


1. Zinc Pyrithione (Antidandruff) has Antibacterial Effects
Research published in the Journal of Drugs in Dermatology indicates that the particles in Zinc Pyrithione (Antidandruff) interact with surface fungal and bacteria cells to control their population.
By fighting the growth of these invaders, Zinc Pyrithione (Antidandruff) improves conditions that impact the skin and scalp.


2. Zinc Pyrithione (Antidandruff) works as an Antifungal Agent
Zinc Pyrithione (Antidandruff) is the most widely used ingredient in medicated shampoos and soaps because of its powerful antifungal effects.
Research shows that Zinc Pyrithione (Antidandruff) is delivered as a micro-particle into the inner layers of skin, allowing it to inhibit fungal activity and improve inflammatory skin conditions, such as fungal acne and dandruff.


3. Zinc Pyrithione (Antidandruff) reduces Dandruff
A 2018 study published in Scientific Reports found that Zinc Pyrithione (Antidandruff) inhibits the growth of M. restricta, a fungus that commonly causes dandruff.

Researchers found that Zinc Pyrithione (Antidandruff) treatment significantly reduced the expression of enzymes that’s activity contribute to the survival of these fungi on human skin.
Zinc Pyrithione (Antidandruff) also proved to improve dandruff by increasing cellular zinc levels.


4. Zinc Pyrithione (Antidandruff) may Improve Hair Growth
A controlled trial published in the British Journal of Dermatology found that 1 percent Zinc Pyrithione (Antidandruff) shampoo improved hair growth when it was used daily for 26 weeks.
Researchers believe that this may be due to Zinc Pyrithione (Antidandruff)’s antifungal and antibacterial effects.


5. Zinc Pyrithione (Antidandruff) soothes Skin Irritation and Itchiness
Research indicates that Zinc Pyrithione (Antidandruff) inhibits the growth of fungus and antimicrobials that cause uncomfortable skin conditions.
Zinc Pyrithione (Antidandruff) helps relive itchiness, redness and irritation that often come with inflammatory conditions, like fungal acne, dandruff, psoriasis and seborrheic dermatitis.


6. Zinc Pyrithione (Antidandruff) regulates Oil Production
Conditions like seborrheic dermatitis can cause skin dryness and oiliness at the same time.
By inhibiting the growth of yeast that causes this condition, Zinc Pyrithione (Antidandruff) helps regulate oil production in the skin and improve the greasiness that can be associated with it.



FUNCTIONS OF ZINC PYRITHIONE (ANTIDANDRUFF):
*Anti-dandruff
*Antiseptic
*Antibacterial
*Anti-Seborrheic
*Anti-Sebum
*Hair conditioning
*Preservative



BENEFITS OF ZINC PYRITHIONE (ANTIDANDRUFF) FOR HAIR:
The benefits of Zinc Pyrithione (Antidandruff) extend beyond the skin of the scalp. By improving the health of the scalp, the health of the hair benefits as well.
Zinc Pyrithione (Antidandruff) has the power to treat a variety of issues, including dandruff, itchiness, acne, and scalp psoriasis by targeting the yeast/fungus that is causing the problem.


*Fights dandruff-causing fungus:
The antifungal, antimicrobial, and antibacterial properties stop dandruff at its source.

Zinc Pyrithione (Antidandruff) is naturally anti-inflammatory and is also antifungal and antibacterial,.
Since dandruff is caused directly by an excessive amount of fungus and yeast living on the scalp, by adding the Zinc Pyrithione (Antidandruff), you decrease the fungal buildup on the scalp and alleviate the inflammation causing the dandruff.


*Prevents itching:
Dandruff is one of the leading causes of scalp itchiness.
By preventing dandruff and eliminating the irritating yeast/fungus that causes it, Zinc Pyrithione (Antidandruff) provides itch relief quickly.


*Regulates oil production:
Zinc Pyrithione (Antidandruff) can control the oil production and dandruff often found in those with seborrheic dermatitis.


*Improves overall scalp health:
Dandruff disrupts the health of the scalp by clogging follicles with flakes and by causing inflammation and irritation.
Zinc Pyrithione (Antidandruff) is able to improve the overall health of the scalp by preventing and treating dandruff.


*Promotes hair growth:
Zinc Pyrithione (Antidandruff) has the potential to impact hair growth.
Since a number of thinning hair and hair loss concerns are related to the scalp, Zinc Pyrithione (Antidandruff) can help clear dead skin cells or conditions that prevent hair growth (clogged hair follicles, psoriasis, etc.) and thus promote fuller, healthier hair.

Garshick agrees and points out a study that showed that daily use of 1 percent Zinc Pyrithione (Antidandruff) shampoo over 26 weeks showed an improvement in hair growth.


*Improves overall appearance of hair:
The overall appearance of the hair is heavily influenced by the oiliness of the scalp and the thickness of the hair.
By regulating oil production and encouraging new growth, Zinc Pyrithione (Antidandruff) can boost the overall appearance of the hair.



WHAT HAIR TYPES CAN USE ZINC PYRITHIONE (ANTIDANDRUFF)?
Our experts agree that Zinc Pyrithione (Antidandruff) is safe for all hair types but would be most beneficial for those experiencing dandruff, seborrheic dermatitis, or other scalp conditions that are aggravated by fungus/yeast.

Some formulations of shampoos and topical scalp products include Zinc Pyrithione (Antidandruff) and hydrating and moisturizing ingredients that would be better for those with dry or color-treated hair.

If you don't have dandruff or other scalp conditions, skipping the products with Zinc Pyrithione (Antidandruff) is best.
The only downside is that Zinc Pyrithione (Antidandruff) could ultimately dry out the hair and scalp slightly and upset a healthier scalp microbiome if there is no dandruff or inflammation.

Zinc Pyrithione (Antidandruff) is always best to speak with a medical professional to evaluate the scalp and determine the best course of treatment.
For those with dry or sensitive skin, it is best to slowly incorporate Zinc Pyrithione (Antidandruff) into a routine and use caution as some dryness and irritation may occur.



BENEFITS OF ZINC PYRITHIONE (ANTIDANDRUFF) FOR HAIR:
Zinc Pyrithione (Antidandruff) is an active ingredient commonly used in anti-dandruff shampoos and personal care products to treat scalp conditions such as seborrheic dermatitis and psoriasis.
Zinc Pyrithione (Antidandruff) is a coordination complex of zinc that contains pyrithione, a biocide with antibacterial and antifungal properties.

Zinc Pyrithione (Antidandruff) works by slowing down the growth of skin cells and reducing the production of yeast, which is a major contributor to dandruff and other scalp conditions.
Zinc Pyrithione (Antidandruff) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.

In addition to its use in personal care products, Zinc Pyrithione (Antidandruff) is also used as an industrial biocide to control the growth of algae and other microorganisms in water-based systems such as paints, coatings, and adhesives.

Zinc Pyrithione (Antidandruff) is an active ingredient commonly found in anti-dandruff shampoos and is known for its ability to effectively combat dandruff and other scalp issues.
But Zinc Pyrithione (Antidandruff) has many other benefits for hair as well.

Here are some of the benefits and uses of Zinc Pyrithione (Antidandruff) for hair:

*Controls Dandruff:
Zinc Pyrithione (Antidandruff) is primarily used to control dandruff, which is caused by an overgrowth of a type of yeast called Malassezia on the scalp.
Zinc Pyrithione (Antidandruff) helps to slow down the growth of this yeast, reducing the amount of dandruff on the scalp.


*Soothes Scalp Irritation:
Zinc Pyrithione (Antidandruff) has anti-inflammatory properties that can help to soothe an irritated or itchy scalp.
This makes Zinc Pyrithione (Antidandruff) an effective ingredient for those with sensitive scalps.


*Promotes Hair Growth:
Zinc Pyrithione (Antidandruff) can also help to promote hair growth by reducing inflammation and providing a healthy environment for hair follicles to grow.


*Fights Hair Loss:
Zinc Pyrithione (Antidandruff) can help to fight hair loss by reducing the inflammation in the scalp that can lead to hair shedding.


*Improves Hair Texture:
Zinc Pyrithione (Antidandruff) can help to improve the texture and appearance of hair by removing build-up and excess oil from the scalp, which can weigh down hair and make it look dull.


*Suitable for All Hair Types:
Zinc Pyrithione (Antidandruff) is safe for use on all hair types, including color-treated hair, as it is a gentle yet effective ingredient.


Overall, Zinc Pyrithione (Antidandruff) is an effective ingredient for promoting a healthy scalp and hair growth, making it a great choice for those dealing with dandruff, hair loss, or other scalp issues.



HOW DOES ZINC PYRITHIONE WORK?
Zinc Pyrithione (Antidandruff) works by targeting the fungus Malassezia, which is a common cause of dandruff and other scalp conditions.
Malassezia is a type of yeast that naturally lives on the scalp and feeds on oils secreted by the hair follicles.

Zinc Pyrithione (Antidandruff) works by disrupting the cell membranes of Malassezia, causing it to die off and reducing its ability to reproduce.
In addition to its antifungal properties, Zinc Pyrithione (Antidandruff) also has antibacterial properties that help to eliminate the bacteria that can contribute to scalp odour.

Zinc Pyrithione (Antidandruff) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
Zinc Pyrithione (Antidandruff) works by inhibiting the production of cytokines, which are proteins that contribute to inflammation and can cause itching and flaking.

Overall, Zinc Pyrithione (Antidandruff) works by controlling the growth of yeast and bacteria on the scalp, reducing inflammation, and promoting a healthier scalp environment.
This helps to reduce the symptoms of dandruff and other scalp conditions and improve the overall appearance and health of the hair and scalp.



TREAT DANDRUFF, ZINC PYRITHIONE (ANTIDANDRUFF):
Zinc Pyrithione (Antidandruff), coal tar, salicylic acid… the list goes on.
There are so many ways to treat dandruff – but what makes Zinc Pyrithione (Antidandruff) the world’s number one anti-dandruff ingredient?¹

Dandruff treatment can take one of two approaches:

*treat the symptoms – this is designed to address the visible symptoms like flakes or inflammation.
However, theunderlying cause of dandruff is still working away.


*tackle the cause – here you get to the root of the problem.
By tackling the cause you can achieve more completerelief and prevent the symptoms from reappearing, so it’s a good long-term solution.
Meet the products that just treat the symptoms of dandruff

Those dandruff treatments that merely work on the symptoms include coal tar and salicylic acid.
Coal tar helps to control the skin’s reaction to scalp irritants formed as the microbe Malassezia globosa breaks down naturaloils on the scalp.
So while you might not experience quite as much irritation, those substances are still being produced at the same rate... and could still damage your scalp.

Salicylic acid acts on the actual flakes.
It is designed to help break the bonds between dead skin cells to make them easier to washoff.

But just like coal tar, salicylic acid doesn’t tackle the underlying cause of your itch, irritation, or flakes – so it’s lesseffective against dandruff.
In fact, in clinical testing these products are far less effective at treating flakes than 1% Zinc Pyrithione (Antidandruff) shampoos.

A better long-term solution?
Pyrithione zinc
Easily the best way to treat dandruff and keep it away for good is to use an anti-dandruff shampoo with an active ingredient that tackles the root cause of dandruff.

That’s where Zinc Pyrithione (Antidandruff) comes in.
Zinc Pyrithione (Antidandruff) both removes and helps prevent the formation of scalp irritants, to keep your scalphealthy and comfortable.

With smaller particles, the dandruff-fighting active can:
*give longer lasting protection – because it’s smaller, it goes deeper into the pores, so it doesn’t rinse out and continues to protect you against dandruff long after the shower

*clean better – the small particles help to create more lather as you wash your hair

*leave your hair and scalp healthier – the particles spread more easily across the scalp and stay there for longer, giving your scalp the protection it needs and allowing your hair to grow from a healthier base



ZINC PYRITHIONE (ANTIDANDRUFF) VS. SELENIUM SULFIDE:
Selenium sulfide is a topical antifungal treatment that slows the growth of yeast on the scalp or body.
It’s available in both prescription and OTC forms.
Like Zinc Pyrithione (Antidandruff), it’s also commonly found in antidandruff shampoos, and the two ingredients can complement each other.
Selenium sulfide is known to be a bit stronger and can be irritating if left on the scalp for too long.
It’s naturally a light orange color, so shampoos or skin care products containing selenium sulfide are usually a peachy hue.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE (ANTIDANDRUFF):
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N

Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)

Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Relative vapor density: No data available

Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C

Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0

Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70<5 micron; D100<12 micron
Boiling Point:253.8C at 760 mmHg

flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (<0.1 g/100 mL at 21 C)
Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless

Melting point/freezing point
Melting point/range: 267 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)

Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262

Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (<0.1 g/100 mL at 21 C)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262



FIRST AID MEASURES of ZINC PYRITHIONE (ANTIDANDRUFF):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE (ANTIDANDRUFF):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE (ANTIDANDRUFF):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE (ANTIDANDRUFF):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE (ANTIDANDRUFF):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE (ANTIDANDRUFF):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available

ZINC PYRITHIONE (ZPT)
Zinc Pyrithione (ZPT) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Pyrithione (ZPT) is the active ingredient in several anti-dandruff shampoos.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chemical formula: C10H8N2O2S2Zn


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Zinc Pyrithione (ZPT) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.
UV light slowly breaks down Zinc Pyrithione (ZPT), providing years of protection even in direct sunlight.


Zinc Pyrithione (ZPT) is a fine beige granules.
Zinc Pyrithione (ZPT) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.


Although the exact mechanism of action remains to be fully elucidated, Zinc Pyrithione (ZPT) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.
In addition, Zinc Pyrithione (ZPT) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.


Zinc Pyrithione (ZPT) has been the top choice among anti-dandruff agents around the world for more than 30 years.
Zinc Pyrithione (ZPT)'s potent action against Pityrosporum Ovale, the primary culprit for dandruff, ensures healthy, dandruff-free hair.
Unlike other treatments, Zinc Pyrithione (ZPT) also keeps fungal infections at bay, resulting in a scalp that's not just visibly clean, but truly healthy.


Zinc Pyrithione (ZPT) is a chemical compound of zinc.
Zinc Pyrithione (ZPT) is used as an antifungal and antibacterial agent.
Zinc is a metallic element with the atomic number 30.


It is found in nature most often as the mineral sphalerite.
Though excess zinc in harmful, in smaller amounts it is an essential element for life, as it is a cofactor for over 300 enzymes and is found in just as many transcription factors.


Zinc Pyrithione (ZPT) is a chemical compound used as an antifungal and antibacterial agent.
Zinc Pyrithione (ZPT) is approved for over-the-counter topical use in the United States as a treatment for dandruff.
Zinc Pyrithione (ZPT) is the active ingredient in several anti-dandruff shampoos.


The effectiveness of Zinc Pyrithione (ZPT) is well-established, but as with many modern medicines that have evolved from time-tested remedies, the way the drug actually works is less clear.
If Zinc Pyrithione (ZPT) is used as a preservative in cosmetic and hygiene products the total proportion can be no more than 0,5 %.


Zinc Pyrithione (ZPT) has also started to be used as an active substance in boat hull paint.
Topical Zinc Pyrithione (ZPT) appears to be a safe and effective treatment for psoriasis.
An aerosol preparation of Zinc Pyrithione (ZPT) (0.25%) in a vehicle containing isopropyl myristate appears to be a safe and effective treatment for psoriasis.


Zinc Pyrithione (ZPT) was found to be negative in mutation tests in bacteria and Chinese hamster ovary cells.
Similarly, no chromosomal aberration was observed in human lymphocytes incubated in vitro in the presence of Zinc Pyrithione (ZPT) or in lymphocytes harvested from monkeys.


The mineralization of 4,5-dichloro-2-n-octyl-4-isothiazolin-3-on (DCOI) and Zinc Pyrithione (ZPT) was examined in laboratory tests with marine coastal sediments.
Zinc Pyrithione (ZPT) has been used as a booster biocide in antifouling paints of ships.


For its environmental risk assessment, a direct analyzing technique of Zinc Pyrithione (ZPT) has been developed using HPLC-MS without transforming to other substances.
Zinc Pyrithione (ZPT) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Zinc Pyrithione (ZPT) works against the viability of bacteria and fungi.
Zinc Pyrithione (ZPT) also works against dandruff.
Zinc Pyrithione (ZPT) is a potent antifungal agent in a water suspension format.


Zinc Pyrithione (ZPT) can restrain and sterilize eight moulds, including black mold,aspergillus flavus, aspergillus versicolor,penicillium citrinum, paecilomium varioti bainier,trichoderma viride, chaetomium globasum and cladosporium herbarum; five bacteria, such as E.coli, staphylococcus aureus, bacillus subtilis,bacillus megaterium and pseudomonas fluorescence as well as two yeast fungi which are distillery yeast and bakers’ yeast.


Zinc Pyrithione (ZPT) is an effective inhibitor of microbe growth
including algal, fungal (molds & yeasts) and bacterial (gram-positive & gram-negative).
Zinc Pyrithione (ZPT) is a “coordination complex” of zinc and pyrithione.


Zinc Pyrithione (ZPT) is one of the active ingredients we use in our shampoos.
On the 4th March 2020, the Scientific Committee on Consumer Safety concluded that Zinc Pyrithione (ZPT) is safe when used as an anti-dandruff in rinse-off hair products in a concentration of maximum 1%.


Being subject to several safety evaluations, Zinc Pyrithione (ZPT) was previously found safe as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.
This came as a result of a safety dossier that was submitted by Cosmetics Europe to demonstrate the safety of Zinc Pyrithione (ZPT) as anti-dandruff in rinse-off hair products.



USES and APPLICATIONS of ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.
Zinc Pyrithione (ZPT) has long been used as anti-dandruff agent and widely used in various popular shampoos.
Zinc Pyrithione (ZPT) is supplied as a powder or as a 50% water suspension emulsion.


The fine particle size of Zinc Pyrithione (ZPT) can effectively prevent precipitation and double the antimicrobial effect.
Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively , delay hair aging, control white hair and hair loss generation.


Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus,playing a role in dandruff .
In the pesticide field, Zinc Pyrithione (ZPT) is used mainly to control apple leaf curl and scab, among others.


Zinc Pyrithione (ZPT) is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.
Zinc Pyrithione (ZPT) is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione (ZPT) is widely used as a fungicide for paints and plastics.


Zinc Pyrithione (ZPT) has unique advantages in environmental friendliness and sterilization persistence.
Therefore, Zinc Pyrithione (ZPT) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione (ZPT) is suitable for outdoor coatings and other products that protect against mold and algae.


In addition, Zinc Pyrithione (ZPT) is an effective algaecide.
Zinc Pyrithione (ZPT) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
As an anti-mildew agent, Zinc Pyrithione (ZPT) also has some applications on fabrics.


Therefore, Zinc Pyrithione (ZPT) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.
The optimum process conditions were determined by single-factor and orthogonal tests.


The process parameters of cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Pyrithione (ZPT) anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione (ZPT) is used as an additive to protect paints (such as industrial and marine) against microbe
(algal, fungal and bacterial) and crustacean growth.


Zinc Pyrithione (ZPT) acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.
Zinc Pyrithione (ZPT) can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.


For shampoo to remove dandruff, Zinc Pyrithione (ZPT) can inhibit the growth of gram-positive and negative bacteria and mold.
Zinc Pyrithione (ZPT) can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
In addition, Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil agent, and paint biocide.


As a fungicide for products such as coatings and plastics, Zinc Pyrithione (ZPT) is also widely used.
Anti-dandruff agent uses of Zinc Pyrithione (ZPT): Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)
Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Pyrithione (ZPT): Skin care (creams & lotions), Foot creams and Talcs


Rinse-off body wash products uses of Zinc Pyrithione (ZPT): Bar Soaps, Body wash, Bubble bath
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


Zinc Pyrithione (ZPT) also known as pyrithione zinc, pyrithionium zinc, olmaitin zinc, this zinc complex as early as in the 1930s was synthesized and used as an external antifungal agent or antibacterial agent.
Zinc Pyrithione (ZPT) is white to yellow crystalline powder at room temperature.


Zinc Pyrithione (ZPT) is slight characteristic odor.
Zinc Pyrithione (ZPT) is insoluble in water.
Zinc pyrazide forms insoluble deposits with cationic and non-ionic surfactants and is unstable to light and oxidants, and to acids and bases at higher temperatures.


Zinc Pyrithione (ZPT) is a coordination complex of the zinc ion and pyrithione, a derivative of the naturally occurring antibiotic aspergillic acid with antimicrobial, antifungal and anti-seborrheic effects.
Although the exact mechanism of action remains to be fully elucidated, Zinc Pyrithione (ZPT) appears to interfere with the membrane transport of ions and metabolites, ultimately leading to a loss of metabolic control.


In addition, Zinc Pyrithione (ZPT) causes an influx of copper, leading to a reduction in the activity of iron-sulphur proteins resulting in growth inhibition.
Zinc Pyrithione (ZPT) is used antifungal, antibacterial and antiseborrheic agent used in many shampoos and hair creams.


Zinc Pyrithione (ZPT) is the most popular anti-dandruff ingredient in the world offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Pyrithione (ZPT) products have been providing dandruff relief and improved scalp health for over 50 years.


Zinc Pyrithione (ZPT) is thus used in dandruff shampoos and also in various cosmetics and products against various skin problems.
Zinc Pyrithione (ZPT) is used as an antifungal and antibacterial agent.
Zinc Pyrithione (ZPT) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


Zinc Pyrithione (ZPT) can inhibit the growth of yeast, which is a main factor in dandruff.
As the name suggests, Zinc Pyrithione (ZPT) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.
Zinc Pyrithione (ZPT) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.


Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.


Zinc Pyrithione (ZPT)’s an ingredient in skincare and hair products because of its antibacterial, antimicrobial, and antifungal properties.
Zinc Pyrithione (ZPT) helps prevent the dandruff-causing microbe, Malassezia globosa, from making the substances that irritate your scalp.
The cosmetic ingredient Zinc Pyrithione (ZPT) is frequently used in the formulation of hair conditioners, shampoos, face powders, cleansing products, eyeliners and skin care products.


Zinc Pyrithione (ZPT) is currently regulated as a preservative in rinse-off products (with the exception of oral hygiene products) in a concentration of up to 0.5% in general products and up to 1.0% in hair products.
Moreover, Zinc Pyrithione (ZPT) is also allowed in a concentration up to 0.1% in leave-on hair products.


Zinc Pyrithione (ZPT) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione (ZPT) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.
Zinc Pyrithione (ZPT) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.


Zinc Pyrithione (ZPT) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione (ZPT) is very effective against a wide variety of pathogenic bacteria/fungus.
Sponges: Zinc Pyrithione (ZPT) is an antibacterial treatment for household sponges, as used by the 3M Corporation.


Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
In the cosmetic industry, zinc and zinc salts are used in various products.


Zinc Pyrithione (ZPT) is one of the zinc salts frequently used in hair conditioners, shampoos, face powders, cleaning products, eye pencils, cleaning and skin care products.
It is active against the bacteria E. coli, Zinc Pyrithione (ZPT) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.


Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.
Zinc Pyrithione (ZPT) is used Shampoo for dandruff.
Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.


Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is a preservative against bacteria, fungi, and yeast.


Zinc Pyrithione (ZPT) is unstable in light and in the presence of oxidizing agents.
Zinc Pyrithione (ZPT) is useful in gels, creams, heavy lotions, and talcum powder.
Zinc Pyrithione (ZPT) is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.


Zinc Pyrithione (ZPT) is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.
In recent years, there have been some regulatory updates concerning the use of Zinc Pyrithione (ZPT) in personal care and cosmetic products in Asia and globally.


Zinc Pyrithione (ZPT) is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Additionally, Zinc Pyrithione (ZPT) aids in controlling sebum production, contributing to a healthier scalp environment.


The chemical formula of Zinc Pyrithione (ZPT) is C10H8N2O2S2Zn.
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
Zinc Pyrithione (ZPT) with a high concentration of 48%.


Zinc Pyrithione (ZPT) is a biocide that effectively inhibits the growth of fungi and bacteria, making it a popular ingredient in anti-dandruff shampoos and scalp treatments.
Zinc Pyrithione (ZPT) is known for its ability to control and prevent dandruff and other scalp conditions caused by the overgrowth of certain microorganisms.


Additionally, Zinc Pyrithione (ZPT) can be found in skincare products to address other skin conditions like acne and seborrheic dermatitis due to its antimicrobial properties.
Zinc Pyrithione (ZPT) can stop yeast from growing, which is a major contributor to dandruff.


Zinc Pyrithione (ZPT), as its name implies, is a chemical compound made from zinc and is utilized in a number of hair and skin care products.
Zinc Pyrithione (ZPT), also known as pyrithione zinc, has antibacterial, antimicrobial, and antifungal qualities that can help cure acne, scalp psoriasis, and seborrheic dermatitis (also known as dandruff).


Zinc Pyrithione (ZPT) is anticipated to be ingested in significant quantities during the production of grooming items such soap and shower products, disinfectants, and antiseptic products.
As a result, Zinc Pyrithione (ZPT)'s consumption is predicted to increase at a significant rate, expanding the market size.


-Medicine uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione (ZPT):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (ZPT) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione (ZPT) is an algaecide.

Zinc Pyrithione (ZPT) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione (ZPT) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione (ZPT) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.


-Clothing uses of Zinc Pyrithione (ZPT):
A process to apply Zinc Pyrithione (ZPT) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (ZPT) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (ZPT) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Shampoo uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) shampoo is found in many common anti-dandruff shampoos.
Zinc Pyrithione (ZPT) is antifungal, antibacterial, and antimicrobial, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Cream uses of Zinc Pyrithione (ZPT):
Seborrheic dermatitis often affects the scalp, but Zinc Pyrithione (ZPT) can also cause rough, scaly patches on the skin.
Zinc Pyrithione (ZPT) cream is used to treat seborrheic dermatitis or psoriasis on the body.
For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione (ZPT) followed by a moisturizer.
You can also use the cream daily by applying it in a thin layer to the affected area.


-Face wash uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione (ZPT) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione (ZPT) may help clear acne.



ADVANTAGES OF ZINC PYRITHIONE (ZPT):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Zinc Pyrithione (ZPT) helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Zinc Pyrithione (ZPT) is used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



STRUCTURE OF ZINC PYRITHIONE (ZPT):
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via scission of one Zn-O bond.
Zinc Pyrithione (ZPT) was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



ZINC PYRITHIONE (ZPT) THE WORLD'S NUMBER ONE ANTI-DANDRUFF INGREDIENT?
Zinc Pyrithione (ZPT), coal tar, salicylic acid… the list goes on.
There are so many ways to treat dandruff – but what makes Zinc

Dandruff treatment can take one of two approaches:
*treat the symptoms – this is designed to address the visible symptoms like flakes or inflammation.
However, theunderlying cause of dandruff is still working away.

*tackle the cause – here you get to the root of the problem.
By tackling the cause you can achieve more completerelief and prevent the symptoms from reappearing, so it’s a good long-term solution.
Meet the products that just treat the symptoms of dandruff

Those dandruff treatments that merely work on the symptoms include coal tar and salicylic acid.
Coal tar helps to control the skin’s reaction to scalp irritants formed as the microbe Malassezia globosa breaks down naturaloils on the scalp.
So while you might not experience quite as much irritation, those substances are still being produced at the same rate... and could still damage your scalp.
Salicylic acid acts on the actual flakes.

It is designed to help break the bonds between dead skin cells to make them easier to washoff.
But just like coal tar, salicylic acid doesn’t tackle the underlying cause of your itch, irritation, or flakes – so it’s lesseffective against dandruff.
In fact, in clinical testing these products are far less effective at treating flakes than 1% Zinc Pyrithione (ZPT) shampoos.



ALTERNATIVES OF ZINC PYRITHIONE (ZPT):
*KETOCONAZOLE,
*SELENIUM SULFIDE



WHAT IS ZINC PYRITHIONE (ZPT) USED FOR?
Zinc Pyrithione (ZPT) is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, Zinc Pyrithione (ZPT) effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Pyrithione (ZPT) also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Pyrithione (ZPT)’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



ORIGIN OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is synthesized through a multistep chemical process. Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Pyrithione (ZPT) undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Pyrithione (ZPT) is then filtered, washed, and dried to obtain a fine powder.



WHAT DOES ZINC PYRITHIONE (ZPT) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



SHAMPOO ZINC PYRITHIONE (ZPT) MARKET: OVERVIEW
Zinc Pyrithione (ZPT), also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by Zinc Pyrithione (ZPT).
Zinc Pyrithione (ZPT), as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Pyrithione (ZPT) shampoo.
Zinc Pyrithione (ZPT) is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



ZINC PYRITHIONE (ZPT), A BETTER LONG-TERM SOLUTION?
Zinc Pyrithione (ZPT) is used easily the best way to treat dandruff and keep it away for good is to use an anti-dandruff shampoo with an activeingredient that tackles the root cause of dandruff.

That’s where Zinc Pyrithione (ZPT) comes in.
Zinc Pyrithione (ZPT) both removes and helps prevent the formation of scalp irritants, to keep your scalphealthy and comfortable.

With smaller particles, the dandruff-fighting active can:
*give longer lasting protection – because it’s smaller, Zinc Pyrithione (ZPT) goes deeper into the pores, so it doesn’t rinse out and continues to protect you against dandruff long after the shower

*clean better – the small particles help to create more lather as you wash your hair

*leave your hair and scalp healthier – the particles spread more easily across the scalp and stay there for longer, giving your scalp the protection Zinc Pyrithione (ZPT) needs and allowing your hair to grow from a healthier base



PROPERTIES OF ZINC PYRITHIONE (ZPT):
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



FUNCTIONS OF ZINC PYRITHIONE (ZPT):
*To combat dandruff,
*To control sebum production,
*Zinc Pyrithione (ZPT) helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Pyrithione (ZPT) prevents the development of microorganisms in cosmetic products.
*According to the SCCS (Scientific Committee on Consumer Safety) opinion published in 2014 and 2018, Zinc Pyrithione (ZPT) was found safe to use as an anti-dandruff agent in rinse-off hair care products at a maximum concentration of 2.0%.



WHERE IS ZINC PYRITHIONE (ZPT) FOUND?
Zinc Pyrithione (ZPT) is an antibacterial and antifungal agent.
Zinc Pyrithione (ZPT) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Pyrithione (ZPT) is an antibacterial and antifungal agent.
Zinc Pyrithione (ZPT) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.
Zinc Pyrithione (ZPT) is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.
Zinc Pyrithione (ZPT) products have been providing dandruff relief and improved scalp health for over 50 years.



FUNCTIONS AND PROPERTIES OF ZINC PYRITHIONE (ZPT):
*Mechanism of Pyrithione-Induced Membrane
*Depolarization in Neurospora crassa
*A clinically controled prospective study with histology
*Embryotoxicity of the antifouling biocide zinc pyrithione to sea urchin (Paracentrotus lividus) and mussel (Mytilus edulis)



SHAMPOO ZINC PYRITHIONE (ZPT) MARKET: OVERVIEW
The demand for Zinc Pyrithione (ZPT) from the intended end use industries is anticipated to drive market expansion.
One of the main factors influencing Zinc Pyrithione (ZPT)'s growth is the usage of antibacterial coating in numerous applications, including the food and beverage, textile, and paint and coating sectors for anti-bacterial activity.
A further important element that has been thought to propel the growth of the worldwide Zinc Pyrithione (ZPT) market is the expansion and increased demand for personal care products.



MECHANISM OF ACTION OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



PREPARATION OF ZINC PYRITHIONE (ZPT):
Method 1:
The principle of preparation is that ZnSO4·7H2O reacts with SPT to produce Zinc Pyrithione (ZPT) and sodium sulfate.
Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.
The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain Zinc Pyrithione (ZPT) crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Pyrithione (ZPT) powder.

Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.

Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.

Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Pyrithione (ZPT) with a yield of about 75%.



BACTERICIDAL MECHANISM OF ZINC PYRITHIONE (ZPT):
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Pyrithione (ZPT) varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Pyrithione (ZPT) is not the same as that of many bactericides, as it kills bacteria without being consumed.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE (ZPT):
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)[1]
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0

Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available

Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available

Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų

Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314

HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.



FIRST AID MEASURES of ZINC PYRITHIONE (ZPT):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE (ZPT):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE (ZPT):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE (ZPT):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE (ZPT):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE (ZPT):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC PYRITHIONE (ZPT)
Zinc Pyrithione (ZPT) is slight characteristic odor.
Zinc Pyrithione (ZPT) is insoluble in water.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chem/IUPAC Name: Pyridine-2-thiol-1-oxide, zinc complex (2:1)
Chemical formula: C10H8N2O2S2Zn



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Zinc Pyrithione (ZPT) has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.


It is active against the bacteria E. coli, Zinc Pyrithione (ZPT) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.
Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.


Zinc Pyrithione (ZPT) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (ZPT) is known for its ability to fight dandruff and promote a healthy scalp.
Zinc Pyrithione (ZPT) is a chemical compound consiting of zinc and pyrithione.


Zinc Pyrithione (ZPT) is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.
Zinc Pyrithione (ZPT) is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent.


At room temperature Zinc Pyrithione (ZPT) is white to yellow crystalline powder.
Zinc Pyrithione (ZPT), also known as Pyrithione Zinc, is an antibacterial, antimicrobial, and antifungal agent that can be used to treat dandruff, scalp psoriasis, and acne.


Zinc Pyrithione (ZPT) is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dimer.
Zinc Pyrithione (ZPT) is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.


Zinc Pyrithione (ZPT)offers bactericide-fungicide efficacy.
Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (ZPT)acts as an anti-dandruff and odor-controlling agent.


Zinc Pyrithione (ZPT)offers bactericide-fungicide efficacy.
Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (ZPT)inhibits the growth of a broad spectrum of both Gram-positive and Gram-negative bacteria.


Zinc Pyrithione (ZPT) is slight characteristic odor.
Zinc Pyrithione (ZPT) is insoluble in water.
Zinc Pyrithione (ZPT) is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.


Zinc Pyrithione (ZPT) mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.
Due to low solubility, Zinc Pyrithione (ZPT) released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.


Other uses of Zinc Pyrithione (ZPT) include additive in antifouling outdoor paints and algaecide. While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione (ZPT) has been reported for decades.
Zinc Pyrithione (ZPT)also inhibits the growth of fungi, yeast, mold, and algae.


Zinc Pyrithione (ZPT)is a mixture of ultra-fine particles of zinc pyrithione (ZPT), a dispersant and a stabilizing agent.
Zinc Pyrithione (ZPT)is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and
bacterial (gram-positive & gram-negative).


Zinc Pyrithione (ZPT)is a fungistatic and baceriostatic compound that has a variety of uses.
Zinc Pyrithione (ZPT) has the ability to inhibit the growth of yeast, which is a major cause of dandruff.
If you're struggling with dandruff or other scalp issues, look for hair care products containing Zinc Pyrithione (ZPT) to help alleviate your symptoms and promote a healthy scalp.


Zinc Pyrithione (ZPT) has long been used as anti-dandruff agent and widely used in various popular shampoos.
Zinc Pyrithione (ZPT) is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Pyrithione (ZPT) can effectively prevent precipitation and double the antimicrobial effect.


Zinc Pyrithione (ZPT) is a chemical compound derived from the natural element Zinc.
Zinc Pyrithione (ZPT) was first developed in the 1930s, then synthesized by E. Shaw in 1950.
So while it does draw from the naturally occurring metal, Zinc Pyrithione (ZPT) is ultimately produced in a lab.


Zinc Pyrithione (ZPT) is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione (ZPT) is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.
Zinc Pyrithione (ZPT) works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione (ZPT) works by targeting both local fungi and bacteria residing on the scalp.
This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.


For instance, Zinc Pyrithione (ZPT)’s an essential element in kitchen sponges, preventing the growth of mould.
Zinc Pyrithione (ZPT) is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione (ZPT) is known for its ability to fight dandruff and promote a healthy scalp.


Additionally, Zinc Pyrithione (ZPT) aids in controlling sebum production, contributing to a healthier scalp environment.
The chemical formula of Zinc Pyrithione (ZPT) is C10H8N2O2S2Zn.
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.



USES and APPLICATIONS of ZINC PYRITHIONE (ZPT):
Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione (ZPT) is suitable for outdoor coatings and other products that protect against mold and algae.
In addition, Zinc Pyrithione (ZPT) is an effective algaecide.


Zinc Pyrithione (ZPT)is used in skincare, shampoos, conditioners and leave-on products.
Zinc Pyrithione (ZPT)is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Zinc Pyrithione (ZPT) can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
As an anti-mildew agent, Zinc Pyrithione (ZPT) also has some applications on fabrics.
Therefore, Zinc Pyrithione (ZPT) on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


The optimum process conditions were determined by single-factor and orthogonal tests.
The process parameters of cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Pyrithione (ZPT) mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Pyrithione (ZPT)is used as an additive to protect paints (such as industrial and marine) against
microbe (algal, fungal and bacterial) and crustacean growth.
Zinc Pyrithione (ZPT)acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.


Zinc Pyrithione (ZPT)can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.
Zinc Pyrithione (ZPT)is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Pyrithione (ZPT) anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione (ZPT) is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.


As the name implies, Zinc Pyrithione (ZPT) is generated from the chemical element zinc and is utilized in several haircare and skincare products.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione (ZPT) is used to treat dandruff and seborrheic dermatitis.
Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione (ZPT) works by targeting both local fungi and bacteria residing on the scalp.
This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.


Zinc Pyrithione (ZPT)is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione (ZPT)is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.


Zinc Pyrithione (ZPT)is a highly effective bactericide-fungicide, the anti-dandruff agent establishes the market standard for any active ingredient solutions in anti-dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion's high antimicrobial efficacy combined with the acceptability for human use has made it the agent of choice for anti-dandruff shampoo manufacturers worldwide.


In addition, an important characteristic of this molecule is that Zinc Pyrithione (ZPT)is efficacious against various bacteria species associated with producing odor on the skin.
Zinc Pyrithione (ZPT)is a fungistatic and bacteriostatic compound that has a variety of uses.


Zinc Pyrithione (ZPT)is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).
Zinc Pyrithione (ZPT)is also often used in kitchen sponges as an antibacterial treatment.


UV light slowly breaks down Zinc Pyrithione (ZPT), providing years of protection even in direct sunlight.
In the pesticide field, Zinc Pyrithione (ZPT) is used mainly to control apple leaf curl and scab, among others.
Zinc Pyrithione (ZPT) is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.


Zinc Pyrithione (ZPT) is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione (ZPT) is widely used as a fungicide for paints and plastics.
Zinc Pyrithione (ZPT) has unique advantages in environmental friendliness and sterilization persistence.


Therefore, Zinc Pyrithione (ZPT) has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Zinc Pyrithione (ZPT) can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.
As the name suggests, Zinc Pyrithione (ZPT) is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.


Pharmaceutical Applications of Zinc Pyrithione (ZPT): Zinc Pyrithione (ZPT) is a regulator of keratinization, has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).
Zinc Pyrithione (ZPT) has a strong killing effect on fungi and bacteria, can effectively kill the fungus that produces dandruff, and has an anti-dandruff effect.


Zinc Pyrithione (ZPT) is used as a bactericide for coatings and plastics, etc.
Zinc Pyrithione (ZPT) is used in shampoos to remove dandruff, and can inhibit the growth of Gram-positive and negative bacteria and molds.
Zinc Pyrithione (ZPT) can effectively care for the hair, delay the aging of the hair, and control the generation of gray hair and hair loss.


Zinc Pyrithione (ZPT) has strong killing power on fungi and bacteria, can effectively kill the fungi that produce dandruff, and play an anti-dandruff effect.
Zinc Pyrithione (ZPT), as an anti-dandruff agent with a long history, is widely known in the shampoo industry and used by many well-known brands.


In addition, Zinc Pyrithione (ZPT) is used in paint to prevent fouling and plugging.
This paint is harmless to the human body and the sea water environment, has a good anti-fouling effect on the organism, and can effectively prevent the sea The equipment is fouled.


In addition, Zinc Pyrithione (ZPT) can be used to treat peeling, such as psoriasis, dermatitis and similar skin diseases.
Zinc Pyrithione (ZPT) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.


Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.
For shampoo to remove dandruff, Zinc Pyrithione (ZPT) can inhibit the growth of gram-positive and negative bacteria and mold.


Zinc Pyrithione (ZPT) can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
In addition, Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil agent, and paint biocide.
Zinc Pyrithione (ZPT) is used as a fungicide for products such as coatings and plastics, it is also widely used.


Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging,control white hair and hair loss generation.
Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, and paint biocide.


Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus, playing a role in dandruff .
Zinc Pyrithione (ZPT) is used Shampoo for dandruff.
Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively , delay hair aging ,control white hair and hair loss generation.


Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is used as anti-dandruff agent and bactericide in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.


Zinc Pyrithione (ZPT) is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Anti-dandruff agent uses of Zinc Pyrithione (ZPT): Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)
Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Pyrithione (ZPT): Skin care (creams & lotions), Foot creams and Talcs


Rinse-off body wash products uses of Zinc Pyrithione (ZPT): Bar Soaps, Body wash, Bubble bath
Zinc Pyrithione (ZPT) is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.
Zinc Pyrithione (ZPT) is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.


In recent years, there have been some regulatory updates concerning the use of Zinc Pyrithione (ZPT) in personal care and cosmetic products in Asia and globally.
Zinc Pyrithione (ZPT) is active against the bacteria E. coli, Zinc pyrithione reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.


Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.
Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.


Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.
Zinc Pyrithione (ZPT) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.


Zinc Pyrithione (ZPT) is very effective against a wide variety of pathogenic bacteria/fungus.
Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
Sponges: Zinc Pyrithione (ZPT) is an antibacterial treatment for household sponges, as used by the 3M Corporation.


-Zinc pyrithione shampoo:
Zinc Pyrithione (ZPT) shampoo is found in many common anti-dandruff shampoos.
Zinc Pyrithione (ZPT) is antifungal, antibacterial, and antimicrobialTrusted Source, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Zinc Pyrithione (ZPT) cream:
Seborrheic dermatitis often affects the scalp, but it can also cause rough, scaly patches on the skin.
Zinc Pyrithione (ZPT) cream is used to treat seborrheic dermatitis or psoriasisTrusted Source on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione (ZPT) followed by a moisturizer.
You can also use the cream daily by applying Zinc Pyrithione (ZPT) in a thin layer to the affected area.


-Clothing uses of Zinc Pyrithione (ZPT):
A process to apply Zinc Pyrithione (ZPT) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (ZPT) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (ZPT) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Zinc pyrithione face wash:
Zinc Pyrithione (ZPT) face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione (ZPT) can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione (ZPT) may help clear acne.


-Medicine uses of Zinc Pyrithione (ZPT):
Zinc Pyrithione (ZPT) can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione (ZPT):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (ZPT) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione (ZPT) is an algaecide.

Zinc Pyrithione (ZPT) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione (ZPT) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione (ZPT) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges: Zinc Pyrithione (ZPT) is an antibacterial treatment for household sponges, as used by the 3M Corporation.
Zinc Pyrithione (ZPT) is a coordination complex of zinc.
Zinc Pyrithione (ZPT) has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


-Clothing uses of Zinc Pyrithione (ZPT):
A process to apply Zinc Pyrithione (ZPT) to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione (ZPT) is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione (ZPT) protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Medicine uses of Zinc Pyrithione (ZPT):
Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione (ZPT) also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione (ZPT)'s other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione (ZPT):
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione (ZPT) is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione (ZPT) is an algaecide.

Zinc Pyrithione (ZPT) is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione (ZPT) is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione (ZPT) is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.



WHAT IS ZINC PYRITHIONE (ZPT) USED FOR?
Zinc Pyrithione (ZPT) is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, this ingredient effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Pyrithione (ZPT) also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Pyrithione (ZPT)’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



HOW TO USE ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is easily found in many drugstore and supermarket shampoo products.
There are also leave-in treatments available from retail haircare lines.
Depending on the severity of your condition, your dermatologist may recommend a stronger treatment that may need a prescription.


*Use in an anti-dandruff shampoo:
Zinc Pyrithione (ZPT) is most often found in anti-dandruff shampoos.
For best results, you should wet your hair and massage the shampoo into your scalp.

Let Zinc Pyrithione (ZPT) sit for approximately one minute (or as instructed on the shampoo label) before shampooing the rest of your hair and then rinse out.

Usage will depend on the sensitivity and state of your scalp.
While many shampoos containing Zinc Pyrithione (ZPT) can be used daily, I typically recommend using it at least two to three times per week.
For some individuals dealing with seborrheic dermatitis or dandruff,

I often recommend washing the scalp daily or every other day to help eliminate the build-up of oils or dead skin, which may contribute to scaling or flaking.
If someone is concerned about dryness of the scalp, it is okay to use a Zinc Pyrithione (ZPT) shampoo a few days per week and a non-medicated shampoo on the alternating days.


*Use in a hydrating conditioner:
Conditioners with Zinc Pyrithione (ZPT) can help fight dandruff, itch, and flaking while restoring scalp balance and providing hydration.
After shampooing, massage the conditioner into your scalp and hair and cover Zinc Pyrithione (ZPT) with a shower cap.
Leave on for 3 minutes and wash out.
Follow the instructions on the label for the best results.


*Relieve itch and flakes with a serum:
Serums with Zinc Pyrithione (ZPT) are great for those with oily scalps or severe flaking and dandruff.
Apply the serum to the scalp in between washes to help with itch and flakes.
Follow the directions on the product, but most can be applied several times a day.


*Apply in a scalp-soothing leave-in cream:
If your scalp tends to get dry, a leave-in cream is often more soothing and moisturizing than a serum.
The creams are often infused with hydrating products like vitamin E and argan oil to protect and moisturize, while the Zinc Pyrithione (ZPT) relieves dandruff, itch, and irritation.



APPEARANCE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is a milky white suspension
Zinc Pyrithione (ZPT)is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.



FUNCTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is best known for its use in treating dandruff and seborrhoeic dermatitis.



KEY PRODUCT ATTRIBUTES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
– Relieves flaking symptoms of dandruff
– Targets scalp with a slow release for highest efficacy
– Effective dispersion because it is not soluble
– Enhances substantivity to the skin and hair
– Maintains efficacy over long-term use without resistance



GENERAL PROPERTIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)Antimicrobial:
– Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent
– Zinc Pyrithione (ZPT)inhibits the growth of a broad spectrum of both Gram positive and Gram negative bacteria
– Zinc Pyrithione (ZPT)inhibits the growth of fungi, both yeast and mold
– Zinc Pyrithione (ZPT)inhibits the growth of algae



KEY PRODUCT ATTRIBUTES FOR ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)relieves flaking symptoms of dandruff
Zinc Pyrithione (ZPT)targets scalp with a slow release for highest efficacy
Effective dispersion because Zinc Pyrithione (ZPT)is not soluble
Zinc Pyrithione (ZPT)enhances substantivity to the skin and hair
Zinc Pyrithione (ZPT)maintains efficacy over long-term use without resistance



STRUCTURE OF ZINC PYRITHIONE (ZPT):
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Zinc Pyrithione (ZPT) was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



MECHANISM OF ACTION OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



FUNCTIONS OF ZINC PYRITHIONE (ZPT) ARE:
*To combat dandruff,
*To control sebum production,
*Zinc Pyrithione (ZPT) helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Pyrithione (ZPT)prevents the development of microorganisms in cosmetic products.



GENERAL PROPERTIES AND APPLICATIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione (ZPT)is an effective antidandruff agent.
Zinc Pyrithione (ZPT)is the growth of a broad spectrum of both Gram positive and Gram negative bacteria.
Zinc Pyrithione (ZPT)inhibits the growth of fungi, both yeast and mold.
Zinc Pyrithione (ZPT)inhibits the growth of algae.



CHEMICAL INCOMPATIBILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Transchelation occurs in the presence of heavy metal ions.
Even traces of the corresponding chelates can cause a noticeable discoloration, foremost the iron and copper complexes.
Zinc Pyrithione (ZPT)is sensitive to strong oxidizing and reducing agents.

The Conductivity of water should be less than 5μs/cm Calculate the dosage to ensure that whole barrels of product would be added for each batch.
It is recommended to add a little zinc salt to the water to ovoid occurring Fe(III) complexes when the conductivity of the water is less than 20μs/cm.
Zinc Pyrithione (ZPT)is incompatible with EDTA, which, however, does no harm the sterilizing effect of Zinc pyrithione



STABILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)remains stable for 120 hours at 100℃, decomposes at 240℃。
Zinc Pyrithione (ZPT)is sensitive to light and remains stable in pigmented coatings.
Zinc Pyrithione (ZPT)is hydrolytically stable between pH 4.5 and 9.5.
Below pH 4.5 conversion to pyrithione occurs.
In alkaline solutions (pH > 9.5) conversion to soluble alkali salts occurs.



PRECAUTIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Stores Zinc Pyrithione (ZPT)in original container in a dry and cool area away from direct sunlight with temperature between 10℃ and 54℃.
Keep the Zinc Pyrithione (ZPT)container tightly closed and sealed until ready for use.

Containers opened must be carefully resealed and kept upright to prevent leakage.
Agitate the barrels every 6 weeks.
Pre-agitate for at least 10 minutes before using.

May be pre-dispersed by a certain amount of water to assure better dispersion.
Calculate the dosage to ensure that whole barrels of the product are added for each batch.



PRODUCT BACKGROUND OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione (ZPT)is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.



BENEFITS OF ZINC PYRITHIONE (ZPT) FOR HAIR:
Zinc Pyrithione (ZPT) is an active ingredient commonly used in anti-dandruff shampoos and personal care products to treat scalp conditions such as seborrheic dermatitis and psoriasis.
Zinc Pyrithione (ZPT) is a coordination complex of zinc that contains pyrithione, a biocide with antibacterial and antifungal properties.

Zinc Pyrithione (ZPT) works by slowing down the growth of skin cells and reducing the production of yeast, which is a major contributor to dandruff and other scalp conditions.

Zinc Pyrithione (ZPT) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
In addition to its use in personal care products, Zinc Pyrithione (ZPT) is also used as an industrial biocide to control the growth of algae and other microorganisms in water-based systems such as paints, coatings, and adhesives.



HOW DOES ZINC PYRITHIONE (ZPT) WORK?
Zinc Pyrithione (ZPT) works by targeting the fungus Malassezia, which is a common cause of dandruff and other scalp conditions.
Malassezia is a type of yeast that naturally lives on the scalp and feeds on oils secreted by the hair follicles.

Zinc Pyrithione (ZPT) works by disrupting the cell membranes of Malassezia, causing it to die off and reducing its ability to reproduce.
In addition to its antifungal properties, Zinc Pyrithione (ZPT) also has antibacterial properties that help to eliminate the bacteria that can contribute to scalp odour.

Zinc Pyrithione (ZPT) also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
Zinc Pyrithione (ZPT) works by inhibiting the production of cytokines, which are proteins that contribute to inflammation and can cause itching and flaking.

Overall, Zinc Pyrithione (ZPT) works by controlling the growth of yeast and bacteria on the scalp, reducing inflammation, and promoting a healthier scalp environment.
This helps to reduce the symptoms of dandruff and other scalp conditions and improve the overall appearance and health of the hair and scalp.



ACTIVITIES OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
It is active against the bacteria E. coli, Zinc Pyrithione (ZPT) reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.

Formulations containing Zinc Pyrithione (ZPT) have been used in the treatment of dandruff.
Shampoo for dandruff, Zinc Pyrithione (ZPT) can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively, delay hair aging, control white hair and hair loss generation.
Zinc Pyrithione (ZPT) is also used as a cosmetic preservative, oil, paint biocide.

Zinc Pyrithione (ZPT) has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione (ZPT) is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione (ZPT) is very effective against a wide variety of pathogenic bacteria/fungus.



MECHANISM OF ACTION OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT)'s antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



WHERE IS ZINC PYRITHIONE (ZPT) FOUND?
Zinc Pyrithione (ZPT) is an antibacterial and antifungal agent.
Zinc Pyrithione (ZPT) is found in dandruff shampoo and cosmetic products for the treatment of skin problems.



BENEFITS AND USES OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is highly effective, keeping in mind that it is gentle and mild on the skin.
Many anti-dandruff shampoos contain Zinc Pyrithione (ZPT).

Zinc Pyrithione (ZPT) is antifungal, antibacterial, and antimicrobial, which means it can fight fungus, bacteria, and germs that cause itchy, flaky skin on the scalp.

Zinc Pyrithione (ZPT) cream is used to treat psoriasis and seborrheic dermatitis also called dandruff.
Face washes containing Zinc Pyrithione (ZPT) can help relieve the redness and irritation caused by seborrheic dermatitis on the face.
Zinc Pyrithione (ZPT) can also assist with the greasiness that comes with eczema and seborrheic dermatitis.



WHAT IS ZINC PYRITHIONE (ZPT), AND WHAT IS ZINC PYRITHIONE (ZPT) USED FOR?
Zinc Pyrithione (ZPT) is a chemical compound with antifungal and antimicrobial properties, used to treat seborrheic dermatitis and dandruff.
Seborrheic dermatitis is believed to result from an inflammatory skin reaction to the overgrowth of Malessezia yeast that commonly lives on the skin surface.

Seborrheic dermatitis causes redness, itching, and skin flaking, including dandruff on the scalp.
Zinc Pyrithione (ZPT) is also used off-label to treat tinea versicolor, another fungal skin infection.
Zinc Pyrithione (ZPT) is commonly used as the main active ingredient in anti-dandruff shampoos, conditioners, soaps, lotions, and creams available over the counter (OTC).

Zinc Pyrithione (ZPT) inhibits yeast growth by increasing the cellular levels of copper and damaging iron-sulfur clusters of proteins that are essential for fungal metabolism and growth.
Zinc Pyrithione (ZPT) has a broad spectrum of activity against organisms including fungi, and gram-positive and gram-negative bacteria.



ZINC AND ZINC PYRITHIONE:
Zinc is a trace mineral, vital to the human body and all forms of life, having catalytic, structural and regulatory functions.
Nevertheless, high levels of dietary zinc can cause anemia, decreased absorption levels of copper and iron, and reduction of enzyme activities in several tissues.
In 2003, the Scientific Committee on Food (SCF) established a tolerable total uptake level (UL) of Zinc up to 25 mg.

In the cosmetic industry, Zinc and zinc salts are used in a variety of categories.
Cosmetic products might account for maximum 10% of the UL.
One of the most widely used zinc salt is Zinc Pyrithione.

It is an aromatic Zinc Pyrithione (ZPT) used as an antidandruff, antiseborrhoeic, hair conditioning agent and preservative in cosmetics and personal care products.
Zinc Pyrithione (ZPT) has been used for more than 60 years as an anti-dandruff agent in concentration up to 1-2%.

In the European Union (EU), in accordance with the European Cosmetic Regulation No. 1223/2009,, Zinc Pyrithione (ZPT) is included in the list of substances which cosmetic products must not contain except subject to the restrictions laid down.
According to same Regulation, Zinc Pyrithione is also included in the Annex V (list of preservatives allowed in cosmetic products), and may be used as a preservative in rinse-off products (excluding oral hygiene products) in a concentration up to 1% in hair products and 0.5% in other products.

The U.S. Food and Drug Administration (FDA) allows the use of Zinc Pyrithione as an active ingredient in Over-The-Counter (OTC) dandruff and seborrheic dermatitis drug products.



WHAT IS ZINC PYRITHIONE (ZPT) USED FOR AND HOW DOES ZINC PYRITHIONE (ZPT) WORK?
Zinc Pyrithione (ZPT) is an over-the-counter (OTC) product used to treat dandruff (seborrhea).



HOW ZINC PYRITHIONE (ZPT) WORKS?
Zinc Pyrithione (ZPT) works by inhibiting the growth of yeast, which is the main factor in dandruff.
Zinc Pyrithione (ZPT) works by supplying moisture to the skin and scalp, thereby hydrating them.



CONCENTRATION AND SOLUBILITY OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is recommended that it be used at a concentration of 0.5 to 1% for best results.
Zinc Pyrithione (ZPT) is soluble in water and alcohol but insoluble in volatile oils.



HOW TO USE ZINC PYRITHIONE (ZPT):
Mix Zinc Pyrithione (ZPT) with water in the recommended concentration and stir until a homogeneous mixture is created.
Add other surfactants and enhancing ingredients like essential oils, depending on your product and need, and mix properly.
Add this mixture to the warm base of the product and stir until the desired thickness and texture are obtained.



ADVANTAGES OF ZINC PYRITHIONE (ZPT):
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



ALTERNATIVES OF ZINC PYRITHIONE (ZPT):
*KETOCONAZOLE,
*SELENIUM SULFIDE



SAFETY PROFILE OF ZINC PYRITHIONE (ZPT):
While generally safe for topical use, Zinc Pyrithione (ZPT) may cause mild side effects such as skin irritation, redness, or dryness, especially in individuals with sensitive skin.
Prolonged or excessive use can exacerbate these symptoms.
Additionally, some people may experience allergic reactions characterized by itching or swelling.
Zinc Pyrithione (ZPT) is advisable to perform a patch test before widespread application and discontinue use if adverse reactions occur.



ORIGIN OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is synthesized through a multistep chemical process.
Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Pyrithione (ZPT) undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Pyrithione (ZPT) is then filtered, washed, and dried to obtain a fine powder.



WHAT DOES ZINC PYRITHIONE (ZPT) DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



TYPE OF INGREDIENT OF ZINC PYRITHIONE (ZPT):
*Antifungal,
*antimicrobial,
*antibacterial properties



MAIN BENEFITS OF ZINC PYRITHIONE (ZPT):
Treats dandruff, soothes scalp irritation, regulates oil production, and prevents itching.



WHO SHOULD USE ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is best for those experiencing dandruff or seborrheic dermatitis, which may be associated with an oily scalp.
It is best to consult a dermatologist to determine the cause of your scalp flakes or irritation before using Zinc Pyrithione (ZPT).



HOW OFTEN CAN YOU USE ZINC PYRITHIONE (ZPT):
Shampoos containing Zinc Pyrithione (ZPT) can be used daily, and those individuals dealing with seborrheic dermatitis or dandruff are often advised to cleanse daily.
If the scalp is dry, it is okay to use a Zinc Pyrithione (ZPT) shampoo two to three days per week and a non-medicated shampoo on alternating days.



ZINC PYRITHIONE (ZPT) WORKS WELL WITH:
Selenium sulfide, another ingredient commonly found in dandruff shampoos stronger than Zinc Pyrithione (ZPT).
Additionally, some individuals may alternate with other Zinc Pyrithione (ZPT) ingredients, such as ketoconazole, an antifungal ingredient.



DON’T USE WITH:
There are no known ingredients that negatively interfere with Zinc Pyrithione (ZPT); however, it is advised that you speak to a medical professional before using if you are pregnant or nursing.



PREPARATION OF ZINC PYRITHIONE (ZPT):
Method 1:
The principle of preparation is that ZnSO4·7H2O reacts with SPT to produce Zinc Pyrithione (ZPT) and sodium sulfate.

Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.

The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain
Zinc Pyrithione (ZPT) crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Pyrithione (ZPT).


Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.


Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.


Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Pyrithione (ZPT) with a yield of about 75%.



WHAT HAIR TYPES CAN USE ZINC PYRITHIONE (ZPT)?
Experts agree that Zinc Pyrithione (ZPT) is safe for all hair types but would be most beneficial for those experiencing dandruff, seborrheic dermatitis, or other scalp conditions that are aggravated by fungus/yeast.

Some formulations of shampoos and topical scalp products include Zinc Pyrithione (ZPT) and hydrating and moisturizing ingredients that would be better for those with dry or color-treated hair.

If you don't have dandruff or other scalp conditions, skipping the products with Zinc Pyrithione (ZPT) is best.
The only downside is that Zinc Pyrithione (ZPT) could ultimately dry out the hair and scalp slightly and upset a healthier scalp microbiome if there is no dandruff or inflammation.

Zinc Pyrithione (ZPT) is always best to speak with a medical professional to evaluate the scalp and determine the best course of treatment.
For those with dry or sensitive skin, it is best to slowly incorporate Zinc Pyrithione (ZPT) into a routine and use caution as some dryness and irritation may occur, Garshick explains.
Engelman cautions that it is best to speak to a medical professional if you are pregnant or nursing before using Zinc Pyrithione (ZPT).



BENEFITS OF ZINC PYRITHIONE (ZPT) FOR HAIR:
The benefits of Zinc Pyrithione (ZPT) extend beyond the skin of the scalp.
By improving the health of the scalp, the health of the hair benefits as well.
Zinc Pyrithione (ZPT) has the power to treat a variety of issues, including dandruff, itchiness, acne, and scalp psoriasis by targeting the yeast/fungus that is causing the problem.


*Zinc Pyrithione (ZPT) fights dandruff-causing fungus:
The antifungal, antimicrobial, and antibacterial properties stop dandruff at its source.
Zinc Pyrithione (ZPT) is naturally anti-inflammatory and is also antifungal and antibacterial.
Since dandruff is caused directly by an excessive amount of fungus and yeast living on the scalp, by adding the Zinc Pyrithione (ZPT), you decrease the fungal buildup on the scalp and alleviate the inflammation causing the dandruff.


*Zinc Pyrithione (ZPT) prevents itching:
Dandruff is one of the leading causes of scalp itchiness.
By preventing dandruff and eliminating the irritating yeast/fungus that causes it, Zinc Pyrithione (ZPT) provides itch relief quickly.


*Zinc Pyrithione (ZPT) regulates oil production:
Zinc Pyrithione (ZPT) can control the oil production and dandruff often found in those with seborrheic dermatitis.


*Zinc Pyrithione (ZPT) improves overall scalp health:
Dandruff disrupts the health of the scalp by clogging follicles with flakes and by causing inflammation and irritation.
Zinc Pyrithione (ZPT) is able to improve the overall health of the scalp by preventing and treating dandruff.


*Zinc Pyrithione (ZPT) promotes hair growth:
Zinc Pyrithione (ZPT) has the potential to impact hair growth.
Since a number of thinning hair and hair loss concerns are related to the scalp, Zinc Pyrithione (ZPT) can help clear dead skin cells or conditions that prevent hair growth (clogged hair follicles, psoriasis, etc.) and thus promote fuller, healthier hair.
Garshick agrees and points out a study that showed that daily use of 1 percent Zinc Pyrithione (ZPT) shampoo over 26 weeks showed an improvement in hair growth.


*Zinc Pyrithione (ZPT) improves overall appearance of hair:
The overall appearance of the hair is heavily influenced by the oiliness of the scalp and the thickness of the hair.
By regulating oil production and encouraging new growth, Zinc Pyrithione (ZPT) can boost the overall appearance of the hair.



PROPERTIES OF ZINC PYRITHIONE (ZPT):
Zinc Pyrithione (ZPT) is a clarifying shampoo for dry & dandruff-prone hair.
-Effectively cleanses & purifies hair.
Zinc Pyrithione (ZPT) helps eliminate itching & controls dandruff while visibly reducing flakes and leaves hair fresh & healthy-looking.

It contains Zinc Pyrithione (ZPT) – an active ingredient with antifungal and antibacterial properties, which intensely improves the scalp condition.
Zinc Pyrithione (ZPT) combats dandruff, seborrhoea and other undesirable changes.
In addition, bisabolol has antiseptic and anti-inflammatory properties, which soothe and restore comfort.



SHAMPOO ZINC PYRITHIONE (ZPT) MARKET: OVERVIEW
Zinc Pyrithione (ZPT), also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by it.

Zinc Pyrithione (ZPT), as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Pyrithione (ZPT) shampoo.
Zinc Pyrithione (ZPT) is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



PROPERTIES OF ZINC PYRITHIONE (ZPT):
In the crystalline state, Zinc Pyrithione (ZPT) exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



BACTERICIDAL MECHANISM OF ZINC PYRITHIONE (ZPT):
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Pyrithione (ZPT) varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Pyrithione (ZPT) is not the same as that of many bactericides, as it kills bacteria without being consumed.



HOW TO USE ZINC PYRITHIONE (ZPT):
Apply Zinc Pyrithione (ZPT) to wet hair and massage in.
Rinse thoroughly.
If necessary, repeat the process.
Use Zinc Pyrithione (ZPT) daily or as special treatment.



ZINC PYRITHIONE (ZPT) IN TOPICAL TREATMENTS:
Zinc Pyrithione (ZPT) is an antifungal and antibacterial agent.
That’s what makes Zinc Pyrithione (ZPT) so powerful at fighting dandruff — more on that later.
Here are some of the highlights when it comes to using Zinc Pyrithione (ZPT) in topical treatments.

*Low Solubility:
A key element of Zinc Pyrithione (ZPT)’s power is that it has relatively low solubility, meaning it has staying power on our skin.
Zinc Pyrithione (ZPT) stays on our scalps, even after we’ve rinsed our hair of shampoo so that it can continue to fight fungus.

*Safe For Topical Use:
Most importantly, Zinc Pyrithione (ZPT) is proven to be a safe agent to introduce to our skin.
Thankfully, Zinc Pyrithione (ZPT) has been approved by the FDA as a safe and effective treatment for dandruff for over 60 years.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE (ZPT):
Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262

Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010

Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.

Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010

Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available

Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262


FIRST AID MEASURES of ZINC PYRITHIONE (ZPT):
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE (ZPT):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE (ZPT):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE (ZPT):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE (ZPT):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE (ZPT):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC PYRITHIONE 48%
ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) IUPAC name bis(2-pyridylthio)zinc 1,1'-dioxide ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Other names ZnP, Pyrithione Zinc, Zinc OMADINE, ZnPT , ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CAS Number 13463-41-7 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) monomer: Interactive image ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) dimer: Interactive image ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) ECHA InfoCard 100.033.324 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) 3005837 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) UNII R953O2RHZ5 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CompTox Dashboard (EPA DTXSID7026314 Edit this at Wikidata ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Properties ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Chemical formula C10H8N2O2S2Zn ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Molar mass 317.70 g/mol ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Appearance colourless solid ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Melting point 240 °C (464 °F; 513 K) (decomposition)[1] ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Boiling point decomposes ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Solubility in water 8 ppm (pH 7) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 )(or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.[2] Contents 1.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Structure of the compound 2.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Uses 2.1.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Medical 2.2.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In paint 2.3.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In sponges 2.4.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In clothing 3.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Mechanism of action 4.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Health effects 5.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) See also 6.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) References 7.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) External links ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Structure of the compound The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociate via scission of one Zn-O bond.This compound was first described in the 1930s.Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Uses Medical ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos. It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera. Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In paint Due to its low solubility in water (8 ppm at neutral pH), zinc pyrithione is suitable for use in outdoor paints and other products that provide protection against mildew and algae. It is an effective algaecide. It is chemically incompatible with paints relying on metal carboxylate curing agents. When used in latex paints with water containing high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed. Its decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In sponges ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) In clothing A process to apply ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) to cotton with washable results was patented in the United States in 1984.ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is now used to prevent microbe growth in polyester.Textiles with applied zinc pyrithione ( ÇİNKO PİRİTİON %48 ) protect against odor-causing microorganisms. Export of antimicrobial textiles reached US$497.4 million in 2015. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Mechanism of action Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Health effects ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several antidandruff shampoos. In its industrial forms and strengths, it may be harmful by contact or ingestion. Zinc pyrithione ( ÇİNKO PİRİTİON %48 ) can trigger a variety of responses, such as DNA damage in skin cells. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) See also Selenium disulfide, an active ingredient used in shampoos such as Selsun Blue.Ketoconazole, another antifungal agent used in shampoos.Piroctone olamine, another antifungal agent used in shampoos.ZPT (ZINC PYRITHIONE 48%) ( ÇİNKO PİRİTİON %48 ) is best known for its use in treating dandruff and seborrhoeic dermatitis. It also has antibacterial properties and is effective against many pathogens from the streptococcus and staphylococcus class. Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) is approved for over-the-counter topical use in the United States as a treatment for dandruff. It is the active ingredient in several anti-dandruff shampoos such as Head & Shoulders. However, in its industrial forms and strengths, it may be harmful by contact or ingestion. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Function 1. Used in shampoo dandruff, it can effectively kill produce dandruff of fungi, to play a role of dusting. 2. Also used as a cosmetic preservative agent. 3. Used for Coating biocide. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CAS: 13463-41-7 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Chemical Formula: C10H8N2O2S2Zn ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Molecular Weight: 317.70 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Test Specification WHITE SLIGHTLY VISCOUS LIQUID. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) PH 5% solution = 7.2 (use meter) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Solubility MISCIBLE IN WATER, BUT LIQUID DOES NOT BECOME CLEAR; INSOLUBLE IN ALCOHOL AND ACETONE; SOLUBLE IN DILUTE NAOH. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Specific gravity Z1025, 13463-41-7 SpectrumTM ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ), 48 Percent Aqueous Suspension is a fungistatic and baceriostatic compound that has a variety of uses. It is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH). It is also often used in kitchen sponges as an antibacterial treatment. 48 Percent Aqueous Suspension. Zinc OmadineTM Fine Particle Size (FPS) Fungicide-Algaecide Dispersion (zinc pyrithione)( ÇİNKO PİRİTİON %48 ) Zinc OmadineTM 48% Aqueous Dispersion FPS (Fine Particle Size) offers bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.Zinc OmadineTM products are highly active, broad spectrum antimicrobial agents that are registered around the world for use in both personal care as well as industrial product applications. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) solution for Cosmetic/Antidandruff Additive Product Name: ZINC PYRITHIONE 48%-50% solution( ÇİNKO PİRİTİON %48 - %50 ) ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) CAS No.:13463-41-7 ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Alias: Zinc Pyrithione; Zinc Omadine; Lunacide ZPT 48% Aqueous Dispersion ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Chemical Name: Zinc bis(2-pyridinethiol-1-oxide); Zinc salt of 2-mercaptopyridine-N-oxide ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Biocides, ZPT 48% with the main active ingredient zince pyrithione is effective inhibitors of the growth of fungi and bacteria and also inhibit the growth of molds and yeasts in cosmetic preparations. In addition to this, they exhibit high growth inhibiting activity against a broad spectrum of gram-positive and gram-negative bacteria in cosmetic prepareations. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Lunacide ZPT 48% is 48% aqueous dispersion of Zinc Pyrithione as an active ingredient that has ultra-fine particle of zice pyrithione, a dispersant and a stabilizing agent. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) is a superordinary anti-scale agent and anti-lipid overflow agent. It can effectively eliminate eumycete which produces dandruff, and result in relieving itching, removing dandruff, diminishing phalacrosis and deferring poliosis. Therefore, it is considered as a highly effective and safe product. It will add the value of shampoo and meet the high demands from consumers. For this reason, ZPT is widely used in the production of shampoo. Moreover, as a fine, broad-spectrum, environment-friendly and low toxic antiseptics, it can be used in civil coating, adhesive and carpet. The mixture of ZPT and Cu2O also can be used as marine antifouling coating to prevent adhering of shells, seaweeds and aquatic organisms to hulls. ZPT and its relative products enjoy tremendous potential and broad space in pesticide field with properties of high-efficiency, environmental protection, hypotoxicity and broad-spectrum. General Properties: Lunacide ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ): -is a mixture in water of very fine particles of zinc pyrithione( ÇİNKO PİRİTİON %48 ), a dispersant, and a viscosity control agent. -is and effective antidandruff agent. -exhibits pronounced growth inhibiting activity against a broad spectrum of both Gram positive and Gram negative bacteria in cosmetic preparations. -inhibits the growth of fungi, both yeast and mold, in cosmetic preparations. Specifications: Spec. Lunacide ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) Appearance Off-white aqueous dispersion Odor Mild Assay(%) 48-50% Zinc(%) 9.3-11.3% PH(5% In PH 7 water) 6.5-9.0 Bulk Density(gr/ml) 1.2-1.25 Particle Size D90 ≤1um D100≤5um Function: 1. Used in shampoo dandruff, it can effectively kill produce dandruff of fungi, to play a role of dusting. 2. Also used as a cosmetic preservative agent. 3. Used for Coating biocid Dosage: Antidandruff shampoo:1.0~4.0% depending on customer requirements.Marine paint: 3.0~10.0% by weight depending on paint formulation of customer. It can be used together with cuprous oxide or cuprous thiocyanate as a perfect formulation in marine paint. Therapy Nonprescription antiseborrheic shampoos containing zinc pyrithione( ÇİNKO PİRİTİON %48 ) (Head & Shoulders), selenium sulfide (Head & Shoulders Intensive Treatment), or ketoconazole (Nizoral) are the mainstay of treatment. The shampoo must be rubbed into the wet scalp, rinsed, and then reapplied for 3 to 5 minutes before the final rinse. Patients with inflammatory seborrheic dermatitis that has not responded to shampoos benefit from a topical steroid lotion or gel. High-potency steroids should be used sparingly, particularly on the face. Tacrolimus ointment 0.1% or pimecrolimus cream can be used as steroid sparing agents. Therapy for Seborrheic Dermatitis Initial Shampoos - two or three times per week Zinc pyrithione 1% Selenium sulfide 1% or 2.5% Ketoconazole 1% or 2% Hydrocortisone cream 1% or 2.5% b.i.d. as needed ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Alternative Tacrolimus ointment 0.1% or pimecrolimus cream ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Shampoos The two mainstays of topical treatment of SD are tar shampoos and antiyeast shampoos. Antiyeast shampoos consist, in order of potency, of zinc pyrithione, selenium sulfide 1% (over-the-counter shampoos), selenium sulfide 2.5% (prescription), and ketoconazole shampoos (available over the counter in some countries). Tar shampoos have antiinflammatory and antiyeast activity. Children with seborrheic dermatitis If the child has seborrheic dermatitis and curly thick hair, even blond or red, there is a difficulty in applying a medical shampoo. Zinc pyrithione is the most acceptable antidandruff substance for curly hair, because it leads to less drying and stiffness. Avoid ketoconazole shampoo because it causes more friction between the fibers. Sometimes increasing the frequency of shampooing is enough to treat scalp desquamation, even with a regular product. If a medicated shampoo is needed, alternating regiments may be tried first: 1 day with zinc pyrithione and the next day with regular shampoo. It is necessary to apply a conditioner in both situations and rinse it thoroughly. In some countries, scalp solutions with zinc or salicylic acid are available and may be applied as a seborrheic dermatitis treatment instead of a shampoo. When corticosteroids are needed, lotions or creams are better choices than alcoholic solutions vehicles. Avoid conditioning shampoos for those who present with seborrheic dermatitis. The use of astringents or dry shampoos is popular in some countries and may be an option for those who wear hair locks or braids for long periods. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) for Optimization The procedure presented above illustrates a method for imaging cellular zinc that has been optimized in our lab for a particular dye and a cell type. The variety among biological specimens and subtle differences between different probes necessitate optimization of many parameters, in particular, dye concentration and loading time. Among others properties, the permeability of a dye has a pronounced effect. For example, ZPP1, which is less permeable than ZP1, requires 1- to 3-h incubation to achieve full fluorescence turn-on in HeLa cells following treatment with zinc/pyrithione (Buccella et al., 2011). Additionally, it is desirable to use minimum dye concentration to reduce background fluorescence. During live-cell imaging, reduced illumination is preferred both to maintain cell health and to prevent dye photobleaching. ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) complex is constituted in situ by combining high-purity zinc salt with sodium pyrithione. When a low-affinity probe such as QZ2 is used for imaging intracellular zinc, a substoichiometric amount of ionophore may be used to avoid its competitive binding with zinc inside cells (Nolan et al., 2005).Although it is convenient to apply directly zinc/pyrithione and TPEN stock solutions in DMSO to the culture dish, mixing DMSO and aqueous media generates heat and the slow diffusion of DMSO often causes nonuniform delivery of mobile zinc. In addition, direct addition of the zinc/pyrithione solution to some media such as Neurobasal may result in precipitation (Nolan et al., 2006). To avoid these issues, DMSO solutions can be first diluted into serum-free medium or PBS before addition to the specimen. For example, one may combine DMSO solutions of ZnCl2 and sodium pyrithione in a 1:2 ratio and dilute 10-fold with DMEM; adding 200 μL of this solution to the dish gives a final zinc concentration of 50 μM. Similarly, diluting 20 mM TPEN stock solution 10-fold with serum-free DMEM and adding 100 μL to the stage yield 100 μM final concentration (Nolan et al., 2006). Moreover, we have observed that dye loading by incubation in DMEM containing only 1% FBS gave better imaging results. Treatment Infantile seborrheic dermatitis spontaneously resolves by the end of the 1st year of life. For infants with disfiguring or symptomatic disease, there are several therapeutic alternatives. Topical agents effective against P. ovale include topical ketoconazole in a cream or shampoo base (Cutsem et al, 1990), shampoos containing 1% zinc pyrithione or 1% to 2.5% selenium sulfide, and propylene glycol (Faergemann, 1988). Propylene glycol is a hygroscopic preservative, with antimycotic activity against P. ovale, that has been widely used for more than a century in foods and cosmetics, but can also rarely cause a contact dermatitis. The safety and efficacy of these products have not been established in infants. Nevertheless, widespread availability and popular use have not produced reports of toxicity. Brief application with daily bathing usually is effective and limits excessive percutaneous absorption. Daily application of 0.5% to 1% hydrocortisone cream is another short-term alternative. Topical zinc in the form of ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ), a common ingredient found in antidandruff shampoos, has also been studied for treatment of hair loss. Zinc pyrithione releases zinc ions, which has anti-inflammatory and antioxidant properties. Zinc ions also inhibit 5α-reductase in the skin.45 A RCT compared 5% minoxidil (twice daily), 1% zinc pyrithione (once daily), a combination of both, and placebo in 200 patients with AGA. In the group treated with zinc pyrithione alone, there was a significant increase in total visible hair count by fiber optic microscopy and computer-assisted hair counts after 9 weeks. However, there was no clinically meaningful global improvement noted by either the investigator or the patients. Minoxidil alone or in combination with zinc was more efficacious than zinc shampoo alone.There is a mixture in many shampoo or dandruff products called ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ). This mixture comes from zinc nitrogen oxygen and sulfur and carries antibacterial. It has been used in the world for about eighty years for dandruff and similar scalp ailments.The antibacterial and anti-fugal mixture that prevents oily on the scalp thus consumes the dandruff in the hair to a large extent. This content has a certain frequency according to the density and hair. If it is used more intensively in this use, it may cause serious harm.For this situation, you should consult a dermatologist when your primary comfort appears. After a recommendation from a specialist physician, the situation regarding the frequency and intensity of use becomes clear.ZINC PYRITHIONE 48% content is used against conditions such as dandruff and scaling with its ability to inhibit the growth of mold, fungi and bacteria. There is a wide variety of products that contain this content and although it is not sold with great creep, it is available from many places. It is not possible to find the product that will emerge in an environment with such freedom. Therefore, when determining such a product, the advice you will receive from a specialist doctor may be more beneficial for you as you know that your situation has been reviewed and you have a certain experience. Measures Before using this medicine, you should inform your doctor about the medicines you are currently using, the medicines you are using without a prescription (e.g. vitamins, herbal supplements, etc.), allergies, your past illnesses and your current health condition (e.g. pregnancy, upcoming surgery, etc.) inform. Certain health conditions can make you more susceptible to the side effects of the medication. Take the steps as directed by your doctor or pay attention to what is written on the product. The dosage depends on your condition. If your condition persists or worsens, notify your doctor. Key issues to consult are listed below. Planning to get pregnant, pregnant or breastfeeding If you use other drugs or over the counter products at the same time, the effects of ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) may change. This may increase the risk of side effects or cause the drug to not work properly. Tell your doctor about all medications, vitamins, and herbal supplements you use so your doctor can avoid drug interactions. Zinc Pyrithione( ÇİNKO PİRİTİON %48 ) may interact with the following drugs and products:Sodium calcium edetate Hypersensitivity to ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) is a contraindication. In addition, ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 )should not be used if you have the following conditions: Allergic reactions storage of ZINC PYRITHIONE 48%( ÇİNKO PİRİTİON %48 ) Store medicines at room temperature, away from heat and light. Do not freeze medicines unless it is written on the package insert. Keep medicines out of the reach of children and pets.Do not pour medicines into the toilet or sink unless you are told to do so in the package insert. Drugs disposed in this way can pollute the nature. Please consult your pharmacist or doctor for more details on how to safely discard Zinc Pyrithione. Expired ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 ) Taking a single dose of expired ZINC PYRITHIONE 48% ( ÇİNKO PİRİTİON %48 )is likely to cause an adverse event. Consult your family doctor or pharmacist for appropriate advice or if you feel unwell. Expired drugs will not be effective in treating the conditions on your prescription. In order to stay safe, it is very important not to use expired medications. If you have a chronic illness that requires constant medication, such as heart disease, seizures, and life-threatening allergies, it is even more important to stay in touch with your GP so that you can replace expired medications immediately.Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (that is, it inhibits the division of fungal cells) and bacteriostatic (inhibits bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis.The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers. In the crystalline state, zinc pyrithione exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers. In solution, however, the dimers dissociate via scission of one Zn-O bond.This compound was first described in the 1930s.Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.[medical citation needed] It also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.[medical citation needed] Its other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.Due to its low solubility in water (8 ppm at neutral pH), zinc pyrithione is suitable for use in outdoor paints and other products that provide protection against mildew and algae. It is an effective algaecide. It is chemically incompatible with paints relying on metal carboxylate curing agents. When used in latex paints with water containing high amount of iron, a sequestering agent that will preferentially bind the iron ions is needed. Its decomposition by ultraviolet light is slow, providing years of protection even against direct sunlight.Zinc pyrithione is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.A process to apply zinc pyrithione to cotton with washable results was patented in the United States in 1984.Zinc pyrithione is now used to prevent microbe growth in polyester.Textiles with applied zinc pyrithione protect against odor-causing microorganisms. Export of antimicrobial textiles reached US$497.4 million in 2015.Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.Zinc pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several antidandruff shampoos and body wash gels. In its industrial forms and strengths, it may be harmful by contact or ingestion. Zinc pyrithione can trigger a variety of responses, such as DNA damage in skin cells.1. Zinc pyrithione 48 is high-efficiency, environmental protection, hypotoxicity and broad-spectrum. Pyrithione zinc is mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.3. Exhibits pronounced growth inhibiting activity against a broad spectrum of both Gram positive and Gram negative bacteria in cosmetic preparations.4. ZPT 48 inhibits the growth of fungi, both yeast and mold, in cosmetic preparations.An international questionnaire completed by 722 dermatologists assessed the belief of tachyphylaxis incidence with pyrithione zinc (PTZ)-based shampoos, time course, occurrence relative to active ingredients, and effect of switching products. Two double-blind, randomized, clinical evaluations were conducted, 24- and 48-week studies, whereby a 1% PTZ shampoo, a 2% PTZ shampoo, or a matched placebo control shampoo was used by each subject for the duration of the study. Dermatologists assessed the adherent scalp flaking (scale of 0-10) at baseline and at specified intervals. 64% of responding dermatologists believed tachyphylaxis occurred with PTZ products, and most felt that tachyphylaxis occurred within 3 months of use. Evaluation of mean treatment responses vs. placebo and individual responses as a function of study duration showed a consistent benefit for all products at all time points; therefore, no evidence for tachyphylaxis was found (within 48 weeks of treatment) .Dandruff results from at least three etiologic factors: Malassezia fungi, sebaceous secretions, and individual sensitivity ... Of the three etiologic factors implicated in dandruff, Malassezia, sebaceous triglycerides, and individual susceptibility, Malassezia are the easiest to control. Pyrithione zinc kills Malassezia and all other fungi, and is highly effective against the Malassezia species actually found on scalp. Reduction in fungi reduces free fatty acids, thereby reducing scalp flaking and itch.The efficacy and safety of ketoconazole (KET) 2% and zinc pyrithione (ZPT) 1% in shampoo formulations for the alleviation of severe dandruff and seborrheic dermatitis /were compared/. This open randomized, parallel-group trial began with a 2-week run-in phase during which subjects applied a neutral non-antidandruff shampoo. It was followed by a 4-week randomized treatment phase and a subsequent 4-week follow-up phase without treatment. Shampooing during the treatment period was carried out twice weekly for the KET group and at least twice weekly for the ZPT group in accordance with the label instructions. A total of 343 subjects were recruited to enter the trial. Of the 331 eligible volunteers, 171 were randomized to KET 2% and 160 to ZPT 1%. ... Beneficial effects were evidenced for both medicated shampoos, but the effect was significantly better for KET 2%, which achieved a 73% improvement in the total dandruff severity score compared with 67% for ZPT 1% at week 4 (p < 0.02). The recurrence rate of the disease was also significantly lower following KET 2% treatment than following ZPT 1% treatment ... Both formulations were well tolerated.A patient had had stable psoriasis for 25 years and no any other skin disease. Within 20 days, she developed an aggravated scaly erythematous patch on the scalp, where /an antidandruff/ shampoo had been applied, and simultaneously developed pustular psoriasis on both forearms. Patch testing showed a relevant sensitization to zinc pyrithione, and ... symptomatic aggravation by provocation testing with zinc pyrithione shampoo /was observed/...A case of allergic contact dermatitis to a shampoo containing zinc pyrithione associated with an eruption of pustular psoriasis is reported. The patient had had stable psoriasis for 5 years, and never any other skin disease. Within 1 week she developed severe generalized pustular psoriasis with many lesions where the shampoo was applied. Treatment with cyclosporin, 200 to 300 mg daily, cleared the eruption within 4 weeks, except for psoriasis of the scalp. Extensive patch testing revealed a relevant sensitization to zinc pyrithione ...4. 4= very toxic: probable oral lethal dose (human) 50-500 mg/kg, between 1 teaspoon & 1 oz for 70 kg person (150 lb). ... It appears unlikely that the toxicity of this substance can be attributed solely to its zinc content.Twenty-six mature Yorkshire pigs were used in this study. Radiolabeled zinc pyrithione was applied /dermally/ for 8 hr either as a single dose (50,100, and 400 mg/kg) or as a 5 day repeated dose (100 mg/kg). Serial samples of blood, urine, and feces were taken after dosing. Radioassay of necropsy material, urine, blood, and feces showed recovery of 86.8-98.2% of applied radioactivity. Greater than 90% of recovery was obtained from washings of the application site. Urinary excretion was 3% in animals with intact skin. Levels of radioactivity in blood, urine, and feces returned to background by 48 hours post-application. Dermal Absorption Factor: 3%.After IV admin in rabbits (14)C disappeared from blood rapidly, within 6 hr, 75% was excreted into urine while concentration of (65)Zn remained relatively constant with only 0.5% excreted into urine. Tissue concentration of (65)Zn were about 10 times higher than (14)C. Eight hr after dermal application, 0.5% of (14)C was excreted into urine, and same amount was found in major organs of rabbit. Less than 0.002% of applied (65)Zn was found in urine and 0.008% was found in major organs.Zinc pyridinethione was biotransformed in rabbits, rats, monkeys, and dogs after oral dosing into 2-pyridinethiol 1-oxide S-glucuronide and 2-pyridinethiol S-glucuronide.For zinc 2-pyridinethiol-1-oxide (USEPA/OPP Pesticide Code: 088002) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: Some heavy metals are VERY TOXIC POISONS, especially if their salts are very soluble in water (e.g., lead, chromium, mercury, bismuth, osmium, and arsenic). IMMEDIATELY call a hospital or poison control center and locate activated charcoal, egg whites, or milk in case the medical advisor recommends administering one of them. Also locate Ipecac syrup or a glass of salt water in case the medical advisor recommends inducing vomiting. Usually, this is NOT RECOMMENDED outside of a physician's care. If advice from a physician is not readily available and the victim is conscious and not convulsing, give the victim a glass of activated charcoal slurry in water or, if this is not available, a glass of milk, or beaten egg whites and IMMEDIATELY transport victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, assure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
ZINC PYRITHIONE 48% AQUEOUS DISPERSION
Zinc Pyrithione 48% aqueous dispersion offers bactericide-fungicide efficacy.
Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.


CAS Number: 13463-41-7
EC Number: 236-671-3
MDL Number: MFCD00067336
Chem/IUPAC Name: Pyridine-2-thiol-1-oxide, zinc complex (2:1)
Chemical formula: C10H8N2O2S2Zn



Zinc Pyrithione, 48% Aqueous Dispersion, Zinc Pyrithione 48% Aqueous Dispersion, Zinc Pyritione 48%, Zinc Pyrithione, T/N: Zinc Omadine 48% FPS, Zinc Pyridinethione,



Zinc Pyrithione 48% aqueous dispersion acts as an anti-dandruff and odor-controlling agent.
Zinc Pyrithione, 48% Aqueous Dispersion is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.
Zinc Pyrithione, 48% Aqueous Dispersion is known for its ability to fight dandruff and promote a healthy scalp.


Zinc Pyrithione, 48% Aqueous Dispersion is a chemical compound consiting of zinc and pyrithione.
Zinc Pyrithione 48% aqueous dispersion is insoluble in water.
Zinc Pyrithione 48% aqueous dispersion is an effective antimicrobial to fungi and bacteria, which can effectively kill the fungi that cause dandruff.


Zinc Pyrithione 48% aqueous dispersion has long been used as anti-dandruff agent and widely used in various popular shampoos.
Zinc Pyrithione 48% aqueous dispersion is supplied as a powder or as a 50% water suspension emulsion.
The fine particle size of Zinc Pyrithione 48% aqueous dispersion can effectively prevent precipitation and double the antimicrobial effect.


Zinc Pyrithione 48% aqueous dispersion offers bactericide-fungicide efficacy.
Zinc Pyrithione, 48% Aqueous Dispersion is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione, 48% Aqueous Dispersion exists as a centrosymmetric dimer.


Zinc Pyrithione, 48% Aqueous Dispersion is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Zinc Pyrithione, 48% Aqueous Dispersion mediates its action by increasing the cellular levels of copper, and damaging iron-sulfur clusters of proteins essential for fungal metabolism and growth.


Zinc Pyrithione, 48% Aqueous Dispersion is commonly found in dandruff treatments due to its antifungal, antimicrobial, and antibacterial properties, which fight the source of dandruff flakes and itch.
Zinc Pyrithione, 48% Aqueous Dispersion, also known as Pyrithione Zinc, is an antibacterial, antimicrobial, and antifungal agent that can be used to treat dandruff, scalp psoriasis, and acne.


Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione 48% aqueous dispersion inhibits the growth of a broad spectrum of both Gram-positive and Gram-negative bacteria.
Zinc Pyrithione 48% aqueous dispersion also inhibits the growth of fungi, yeast, mold, and algae.


As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione, 48% Aqueous Dispersion works by targeting both local fungi and bacteria residing on the scalp.
This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.


Zinc Pyrithione 48% aqueous dispersion is the pyrithione complexes of zinc bromide, in the early 1930s, was already synthesized and used as a topical antifungal or antibacterial agent.
At room temperature Zinc Pyrithione 48% aqueous dispersion is white to yellow crystalline powder.


Zinc Pyrithione 48% aqueous dispersion is slight characteristic odor.
Zinc Pyrithione 48% aqueous dispersion is a compound commonly used in cosmetics and personal care products for its antifungal and antibacterial properties.
Zinc Pyrithione 48% aqueous dispersion is an active ingredient designed to treat dandruff, seborrheic dermatitis, and various fungal infections of the skin and scalp.


Zinc Pyrithione 48% aqueous dispersion works by inhibiting the growth of fungi and bacteria that contribute to these conditions, helping to reduce flakiness, itching, and irritation.
Zinc Pyrithione 48% aqueous dispersion is slight characteristic odor.


Zinc Pyrithione 48% aqueous dispersion is insoluble in water.
Zinc Pyrithione 48% aqueous dispersion has antibacterial, antimicrobial, and antifungal properties that can help treat seborrheic dermatitis (also called dandruff), scalp psoriasis, and acne.


Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
It is active against the bacteria E. coli, Zinc Pyrithione 48% aqueous dispersion reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.


Formulations containing Zinc Pyrithione 48% aqueous dispersion have been used in the treatment of dandruff.
For instance, Zinc Pyrithione, 48% Aqueous Dispersion’s an essential element in kitchen sponges, preventing the growth of mould.
Zinc Pyrithione, 48% Aqueous Dispersion is an active ingredient commonly found in anti-dandruff shampoos, conditioners, and other hair care products.


Zinc Pyrithione, 48% Aqueous Dispersion is known for its ability to fight dandruff and promote a healthy scalp.
Zinc Pyrithione 48% aqueous dispersion is a mixture of ultra-fine particles of zinc pyrithione (ZPT), a dispersant and a stabilizing agent.
Zinc Pyrithione 48% aqueous dispersion is an effective inhibitor of microbe growth including algal, fungal (molds & yeasts) and
bacterial (gram-positive & gram-negative).


Due to low solubility, Zinc Pyrithione, 48% Aqueous Dispersion released from the topical formulations is deposited and retained relatively well onto the target skin surfaces.
Other uses of Zinc Pyrithione, 48% Aqueous Dispersion include additive in antifouling outdoor paints and algaecide. While its use has been approved in the early 1960's by the FDA 4, safety and effectiveness of Zinc Pyrithione, 48% Aqueous Dispersion has been reported for decades.


Zinc Pyrithione, 48% Aqueous Dispersion has the ability to inhibit the growth of yeast, which is a major cause of dandruff.
If you're struggling with dandruff or other scalp issues, look for hair care products containing Zinc Pyrithione, 48% Aqueous Dispersion to help alleviate your symptoms and promote a healthy scalp.
Additionally, Zinc Pyrithione 48% aqueous dispersion aids in controlling sebum production, contributing to a healthier scalp environment.


The chemical formula of Zinc Pyrithione 48% aqueous dispersion is C10H8N2O2S2Zn.
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc.
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
Zinc Pyrithione 48% aqueous dispersion is a fungistatic and baceriostatic compound that has a variety of uses.


Zinc Pyrithione, 48% Aqueous Dispersion is a chemical compound derived from the natural element Zinc.
Zinc Pyrithione, 48% Aqueous Dispersion was first developed in the 1930s, then synthesized by E. Shaw in 1950.
So while it does draw from the naturally occurring metal, Zinc Pyrithione, 48% Aqueous Dispersion is ultimately produced in a lab.



USES and APPLICATIONS of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is used in skincare, shampoos, conditioners and leave-on products.
Zinc Pyrithione 48% aqueous dispersion is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.


Due to its low solubility in water (8 ppm at pH 7), Zinc Pyrithione 48% aqueous dispersion is suitable for outdoor coatings and other products that protect against mold and algae.
In addition, Zinc Pyrithione 48% aqueous dispersion is an effective algaecide.


The optimum process conditions were determined by single-factor and orthogonal tests.
The process parameters of cotton fabrics were: Zinc Pyrithione 48% aqueous dispersion mass concentration 0.04g/L, baking time 3min, baking temperature 120℃, 80% ginning rate, bath ratio 1:25; polyester/cotton fabrics were: Zinc Pyrithione 48% aqueous dispersion mass concentration 0.03g/L, baking time 3min, baking temperature 130℃, 80% ginning rate, bath ratio 1:25.


Zinc Pyrithione 48% aqueous dispersion is used as an additive to protect paints (such as industrial and marine) against
microbe (algal, fungal and bacterial) and crustacean growth.
Zinc Pyrithione 48% aqueous dispersion acts as a low metal fouling agent with long-lasting efficacy that does not induce galvanic corrosion making it suitable for metal hulls and marine environments.


Zinc Pyrithione 48% aqueous dispersion can be compounded and applied to ship antifouling coatings to prevent marine life from adhering to the ship’s hull.
As an anti-mildew agent, Zinc Pyrithione 48% aqueous dispersion also has some applications on fabrics.
Therefore, Zinc Pyrithione 48% aqueous dispersion on cotton and polyester/cotton fabrics was investigated under different mass concentrations, baking times, and temperatures.


Zinc Pyrithione 48% aqueous dispersion can be applied to some textiles to prevent microbe growth and used in cosmetics for a variety of skin related benefits including anti-dandruff properties.
Zinc Pyrithione 48% aqueous dispersion is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


UV light slowly breaks down Zinc Pyrithione 48% aqueous dispersion, providing years of protection even in direct sunlight.
In the pesticide field, Zinc Pyrithione 48% aqueous dispersion is used mainly to control apple leaf curl and scab, among others.
Zinc Pyrithione 48% aqueous dispersion is used as an anti-dandruff agent and preservative in cosmetics and is widely used to prepare anti-dandruff shampoos.


In addition, Zinc Pyrithione 48% aqueous dispersion can be used to treat peeling, such as psoriasis, dermatitis and similar skin diseases.
Zinc Pyrithione 48% aqueous dispersion is best known for its use in treating dandruff and seborrhoeic dermatitis, particularly in dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.


Zinc Pyrithione 48% aqueous dispersion is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione 48% aqueous dispersion is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners, and leave-on products.


Pharmaceutical Applications of Zinc Pyrithione 48% aqueous dispersion: Zinc Pyrithione 48% aqueous dispersion is a regulator of keratinization, has antimicrobial properties and ketoconazole is an antifungal agent (i.e.can provide the reduction of the lipophilic yeast Malassezia furfur).
Zinc Pyrithione 48% aqueous dispersion has a strong killing effect on fungi and bacteria, can effectively kill the fungus that produces dandruff, and has an anti-dandruff effect.


Zinc Pyrithione 48% aqueous dispersion's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea, and vitiligo.
For shampoo to remove dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit the growth of gram-positive and negative bacteria and mold.


Zinc Pyrithione 48% aqueous dispersion is used in shampoos to remove dandruff, and can inhibit the growth of Gram-positive and negative bacteria and molds.
Zinc Pyrithione 48% aqueous dispersion can effectively care for the hair, delay the aging of the hair, and control the generation of gray hair and hair loss.


Zinc Pyrithione 48% aqueous dispersion can effectively care for hair, delay hair aging, and control the occurrence of white hair and hair loss.
In addition, Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil agent, and paint biocide.
Zinc Pyrithione 48% aqueous dispersion is used as a fungicide for products such as coatings and plastics, it is also widely used.


Zinc Pyrithione 48% aqueous dispersion is a highly effective bactericide-fungicide, the anti-dandruff agent establishes the market standard for any active ingredient solutions in anti-dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion's high antimicrobial efficacy combined with the acceptability for human use has made it the agent of choice for anti-dandruff shampoo manufacturers worldwide.


Zinc Pyrithione 48% aqueous dispersion anti-mildew agent can play the best anti-mildew effect.
Zinc Pyrithione 48% aqueous dispersion is chemically incompatible with paints that rely on metal carboxylate curing agents.
When used in emulsion paints containing large amounts of iron in water, a chelating agent that preferentially binds iron ions is required.


In addition, an important characteristic of this molecule is that Zinc Pyrithione 48% aqueous dispersion is efficacious against various bacteria species associated with producing odor on the skin.
Zinc Pyrithione 48% aqueous dispersion is a fungistatic and bacteriostatic compound that has a variety of uses.


Zinc Pyrithione 48% aqueous dispersion is mainly used in cosmetics, shampoos, and skin care products.
Zinc Pyrithione 48% aqueous dispersion is widely used as a fungicide for paints and plastics.
Zinc Pyrithione 48% aqueous dispersion has unique advantages in environmental friendliness and sterilization persistence.


Therefore, Zinc Pyrithione 48% aqueous dispersion has a long-term application prospect in the future when emulsion paints are continuously environmentally friendly.
Zinc Pyrithione 48% aqueous dispersion can inhibit the growth of yeastTrusted Source, which is a main factor in dandruff.


As the name suggests, Zinc Pyrithione 48% aqueous dispersion is derived from the chemical element zinc and it’s used in a variety of hair and skin care products.
Shampoo for dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging,control white hair and hair loss generation.


Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, and paint biocide.
Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so it can effectively kill dandruff fungus, playing a role in dandruff .


Zinc Pyrithione 48% aqueous dispersion is used Shampoo for dandruff.
Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively , delay hair aging ,control white hair and hair loss generation.


Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, paint biocide.
Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .


Zinc Pyrithione 48% aqueous dispersion is used as anti-dandruff agent and bactericide in cosmetics, and is widely used in the preparation of anti-dandruff shampoo.
Zinc Pyrithione 48% aqueous dispersion has strong killing power on fungi and bacteria, can effectively kill the fungi that produce dandruff, and play an anti-dandruff effect.


Zinc Pyrithione 48% aqueous dispersion, as an anti-dandruff agent with a long history, is widely known in the shampoo industry and used by many well-known brands.
In addition, Zinc Pyrithione 48% aqueous dispersion is used in paint to prevent fouling and plugging.


This paint is harmless to the human body and the sea water environment, has a good anti-fouling effect on the organism, and can effectively prevent the sea The equipment is fouled.
Rinse-off body wash products uses of Zinc Pyrithione 48% aqueous dispersion: Bar Soaps, Body wash, Bubble bath.


Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione 48% aqueous dispersion is zinc complex of 1-hydroxy-2(1H)-pyridinethione, or more commonly, pyrithione.


Zinc Pyrithione 48% aqueous dispersion is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione 48% aqueous dispersion is very effective against a wide variety of pathogenic bacteria/fungus.
Zinc Pyrithione 48% aqueous dispersion is used as a bactericide for coatings and plastics, etc.


Zinc Pyrithione 48% aqueous dispersion has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.
Sponges: Zinc Pyrithione 48% aqueous dispersion is an antibacterial treatment for household sponges, as used by the 3M Corporation.


As the name implies, Zinc Pyrithione, 48% Aqueous Dispersion is generated from the chemical element zinc and is utilized in several haircare and skincare products.
Due to its dynamic fungistatic and bacteriostatic properties, Zinc Pyrithione, 48% Aqueous Dispersion is used to treat dandruff and seborrheic dermatitis.


Dandruff is a common scalp disease affecting >40% of the world's adult population, and may be caused by fungi such as Malassezia globosa and M. restricta 3.
As the most widely used active component in anti-dandruff shampoos, Zinc Pyrithione, 48% Aqueous Dispersion works by targeting both local fungi and bacteria residing on the scalp.


This multitasking ingredient, known for its cost-effectiveness and efficacy, has uses that extend beyond hair care.
Zinc Pyrithione 48% aqueous dispersion is mainly used in cosmetics, shampoo, skin care, but also used in adhesives, paints, paints, etc.
Anti-dandruff agent uses of Zinc Pyrithione 48% aqueous dispersion: Hair care rinse-off & leave-on products (shampoos, conditioners, gels, creams, etc.)


Anti-fungal/anti-microbial & anti-inflammatory uses of Zinc Pyrithione 48% aqueous dispersion: Skin care (creams & lotions), Foot creams and Talcs.
Zinc Pyrithione 48% aqueous dispersion is used in outdoor paint and other products that provide protection against mildew and algae due to its low solubility in water (8 ppm at neutral pH).


Zinc Pyrithione 48% aqueous dispersion is also often used in kitchen sponges as an antibacterial treatment.
Zinc Pyrithione 48% aqueous dispersion is a common active ingredient found in various personal care and cosmetic products such as shampoos, conditioners, and body washes.


Zinc Pyrithione 48% aqueous dispersion is known for its anti-fungal and anti-bacterial properties, making it an effective ingredient for treating dandruff and other skin conditions.
In recent years, there have been some regulatory updates concerning the use of Zinc Pyrithione 48% aqueous dispersion in personal care and cosmetic products in Asia and globally.


Zinc Pyrithione 48% aqueous dispersion is active against the bacteria E. coli, Zinc pyrithione reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.
Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, paint biocide.


Formulations containing Zinc Pyrithione 48% aqueous dispersion have been used in the treatment of dandruff.Shampoo for dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth, Care hair Effectively, delay hair aging ,control white hair and hair loss generation.



-Zinc pyrithione shampoo:
Zinc Pyrithione 48% aqueous dispersion shampoo is found in many common anti-dandruff shampoos.
Zinc Pyrithione 48% aqueous dispersion is antifungal, antibacterial, and antimicrobialTrusted Source, meaning it can kill fungus, bacteria, and microorganisms that can contribute to an itchy, flaky scalp.


-Zinc Pyrithione 48% aqueous dispersion cream:
Seborrheic dermatitis often affects the scalp, but it can also cause rough, scaly patches on the skin.
Zinc Pyrithione 48% aqueous dispersion cream is used to treat seborrheic dermatitis or psoriasisTrusted Source on the body.

For the treatment of mild seborrheic dermatitis, the National Eczema Foundation suggests daily use of a cleanser that contains 2 percent Zinc Pyrithione 48% aqueous dispersion followed by a moisturizer.
You can also use the cream daily by applying Zinc Pyrithione 48% aqueous dispersion in a thin layer to the affected area.


-Clothing uses of Zinc Pyrithione 48% aqueous dispersion:
A process to apply Zinc Pyrithione 48% aqueous dispersion to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione 48% aqueous dispersion is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione 48% aqueous dispersion protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Zinc pyrithione face wash:
Zinc Pyrithione 48% aqueous dispersion face wash can help alleviate redness and itching associated with seborrheic dermatitis on the face.
Zinc Pyrithione 48% aqueous dispersion can also help alleviate some of the greasiness associated with eczema and seborrheic dermatitis.
There’s some evidence that using a medicated soap that contains 2 percent Zinc Pyrithione 48% aqueous dispersion may help clear acne.


-Medicine uses of Zinc Pyrithione 48% aqueous dispersion:
Zinc Pyrithione 48% aqueous dispersion can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione 48% aqueous dispersion also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.
Zinc Pyrithione 48% aqueous dispersion's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione 48% aqueous dispersion:
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione 48% aqueous dispersion is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione 48% aqueous dispersion is an algaecide.

Zinc Pyrithione 48% aqueous dispersion is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione 48% aqueous dispersion is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione 48% aqueous dispersion is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.

Sponges: Zinc Pyrithione 48% aqueous dispersion is an antibacterial treatment for household sponges, as used by the 3M Corporation.
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc.
Zinc Pyrithione 48% aqueous dispersion has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis and dandruff.


-Clothing uses of Zinc Pyrithione 48% aqueous dispersion:
A process to apply Zinc Pyrithione 48% aqueous dispersion to cotton with washable results was patented in the United States in 1984.
Zinc Pyrithione 48% aqueous dispersion is used to prevent microbe growth in polyester.
Textiles with applied Zinc Pyrithione 48% aqueous dispersion protect against odor-causing microorganisms.
Export of antimicrobial textiles reached US$497.4 million in 2015.


-Medicine uses of Zinc Pyrithione 48% aqueous dispersion:
Zinc pyrithione can be used to treat dandruff and seborrhoeic dermatitis.
Zinc Pyrithione 48% aqueous dispersion also has antibacterial properties and is effective against many pathogens from the Streptococcus and Staphylococcus genera.

Zinc Pyrithione 48% aqueous dispersion's other medical applications include treatments of psoriasis, eczema, ringworm, fungus, athletes foot, dry skin, atopic dermatitis, tinea versicolor, and vitiligo.


-Paint uses of Zinc Pyrithione 48% aqueous dispersion:
Because of its low solubility in water (8 ppm at neutral pH), Zinc Pyrithione 48% aqueous dispersion is suitable for use in outdoor paints and other products that protect against mildew and algae.
Zinc Pyrithione 48% aqueous dispersion is an algaecide.

Zinc Pyrithione 48% aqueous dispersion is chemically incompatible with paints relying on metal carboxylate curing agents.
When Zinc Pyrithione 48% aqueous dispersion is used in latex paints with water containing much iron, a sequestering agent that preferentially binds the iron ions is needed.
Zinc Pyrithione 48% aqueous dispersion is decomposed by ultraviolet light slowly, providing years of protection in direct sunlight.



WHAT IS ZINC PYRITHIONE 48% AQUEOUS DISPERSION USED FOR?
Zinc Pyrithione 48% aqueous dispersion is a beneficial compound owing to its antimicrobial properties and finds extensive application in personal care products and cosmetics.
Primarily utilized in cleansing formulations like shampoos and soap, this ingredient effectively targets dandruff, seborrheic dermatitis, and fungal skin infections by inhibiting the growth of fungi and bacteria responsible for these conditions.

Zinc Pyrithione 48% aqueous dispersion also alleviates symptoms like itching, flaking, and redness on the scalp and skin.
Zinc Pyrithione 48% aqueous dispersion’s ability to regulate microbial balance and control sebum production makes it an essential ingredient in products designed to promote scalp and skin health, offering consumers relief from common dermatological issues with proven efficacy.



HOW TO USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is easily found in many drugstore and supermarket shampoo products.
There are also leave-in treatments available from retail haircare lines.
Depending on the severity of your condition, your dermatologist may recommend a stronger treatment that may need a prescription.


*Use in an anti-dandruff shampoo:
Zinc Pyrithione, 48% Aqueous Dispersion is most often found in anti-dandruff shampoos.
For best results, you should wet your hair and massage the shampoo into your scalp.

Let Zinc Pyrithione, 48% Aqueous Dispersion sit for approximately one minute (or as instructed on the shampoo label) before shampooing the rest of your hair and then rinse out.

Usage will depend on the sensitivity and state of your scalp.
While many shampoos containing Zinc Pyrithione, 48% Aqueous Dispersion can be used daily, I typically recommend using it at least two to three times per week.
For some individuals dealing with seborrheic dermatitis or dandruff,

I often recommend washing the scalp daily or every other day to help eliminate the build-up of oils or dead skin, which may contribute to scaling or flaking.
If someone is concerned about dryness of the scalp, it is okay to use a Zinc Pyrithione, 48% Aqueous Dispersion shampoo a few days per week and a non-medicated shampoo on the alternating days.


*Use in a hydrating conditioner:
Conditioners with Zinc Pyrithione, 48% Aqueous Dispersion can help fight dandruff, itch, and flaking while restoring scalp balance and providing hydration.
After shampooing, massage the conditioner into your scalp and hair and cover Zinc Pyrithione, 48% Aqueous Dispersion with a shower cap.
Leave on for 3 minutes and wash out.
Follow the instructions on the label for the best results.


*Relieve itch and flakes with a serum:
Serums with Zinc Pyrithione, 48% Aqueous Dispersion are great for those with oily scalps or severe flaking and dandruff.
Apply the serum to the scalp in between washes to help with itch and flakes.
Follow the directions on the product, but most can be applied several times a day.


*Apply in a scalp-soothing leave-in cream:
If your scalp tends to get dry, a leave-in cream is often more soothing and moisturizing than a serum.
The creams are often infused with hydrating products like vitamin E and argan oil to protect and moisturize, while the Zinc Pyrithione, 48% Aqueous Dispersion relieves dandruff, itch, and irritation.


STRUCTURE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
The pyrithione ligands, which are formally monoanions, are chelated to Zn2+ via oxygen and sulfur centers.
In the crystalline state, Zinc Pyrithione 48% aqueous dispersion exists as a centrosymmetric dimer (see figure), where each zinc is bonded to two sulfur and three oxygen centers.

In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Zinc Pyrithione 48% aqueous dispersion was first described in the 1930s.
Pyrithione is the conjugate base derived from 2-mercaptopyridine-N-oxide (CAS# 1121-31-9), a derivative of pyridine-N-oxide.



MECHANISM OF ACTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion's antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



FUNCTIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION ARE:
*To combat dandruff,
*To control sebum production,
*Zinc Pyrithione 48% aqueous dispersion helps the hair to be easily combed, soft, shiny and voluminous.
*Zinc Pyrithione 48% aqueous dispersionprevents the development of microorganisms in cosmetic products.



BENEFITS OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION FOR HAIR:
Zinc Pyrithione, 48% Aqueous Dispersion is an active ingredient commonly used in anti-dandruff shampoos and personal care products to treat scalp conditions such as seborrheic dermatitis and psoriasis.
Zinc Pyrithione, 48% Aqueous Dispersion is a coordination complex of zinc that contains pyrithione, a biocide with antibacterial and antifungal properties.

Zinc Pyrithione, 48% Aqueous Dispersion works by slowing down the growth of skin cells and reducing the production of yeast, which is a major contributor to dandruff and other scalp conditions.

Zinc Pyrithione, 48% Aqueous Dispersion also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
In addition to its use in personal care products, Zinc Pyrithione, 48% Aqueous Dispersion is also used as an industrial biocide to control the growth of algae and other microorganisms in water-based systems such as paints, coatings, and adhesives.



ACTIVITIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is a coordination complex of zinc and pyrithione that has antimicrobial and anticancer activities.
It is active against the bacteria E. coli, Zinc Pyrithione 48% aqueous dispersion reduces tumor growth in an SCC-4 mouse xenograft model when administered at a dose of 1 mg per week for six weeks.

Formulations containing Zinc Pyrithione 48% aqueous dispersion have been used in the treatment of dandruff.
Shampoo for dandruff, Zinc Pyrithione 48% aqueous dispersion can inhibit Gram positive and negative bacteria and mold growth,Care hair Effectively, delay hair aging, control white hair and hair loss generation.
Zinc Pyrithione 48% aqueous dispersion is also used as a cosmetic preservative, oil, paint biocide.

Zinc Pyrithione 48% aqueous dispersion has a strong killing power on fungi and bacteria so that it can effectively kill dandruff fungus,playing a role in dandruff .
Zinc Pyrithione 48% aqueous dispersion is used as anti-fungal agent to treat dandruff and seborrheic dermatitis.
Zinc Pyrithione 48% aqueous dispersion is very effective against a wide variety of pathogenic bacteria/fungus.



MECHANISM OF ACTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion's antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism.



WHERE IS ZINC PYRITHIONE 48% AQUEOUS DISPERSION FOUND?
Zinc Pyrithione 48% aqueous dispersion is an antibacterial and antifungal agent.
Zinc Pyrithione 48% aqueous dispersion is found in dandruff shampoo and cosmetic products for the treatment of skin problems.



HOW DOES ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORK?
Zinc Pyrithione, 48% Aqueous Dispersion works by targeting the fungus Malassezia, which is a common cause of dandruff and other scalp conditions.
Malassezia is a type of yeast that naturally lives on the scalp and feeds on oils secreted by the hair follicles.

Zinc Pyrithione, 48% Aqueous Dispersion works by disrupting the cell membranes of Malassezia, causing it to die off and reducing its ability to reproduce.
In addition to its antifungal properties, Zinc Pyrithione, 48% Aqueous Dispersion also has antibacterial properties that help to eliminate the bacteria that can contribute to scalp odour.

Zinc Pyrithione, 48% Aqueous Dispersion also has mild anti-inflammatory properties that help to reduce redness and itching on the scalp.
Zinc Pyrithione, 48% Aqueous Dispersion works by inhibiting the production of cytokines, which are proteins that contribute to inflammation and can cause itching and flaking.

Overall, Zinc Pyrithione, 48% Aqueous Dispersion works by controlling the growth of yeast and bacteria on the scalp, reducing inflammation, and promoting a healthier scalp environment.
This helps to reduce the symptoms of dandruff and other scalp conditions and improve the overall appearance and health of the hair and scalp.



ADVANTAGES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
*An effective, broad-spectrum anti-dandruff compound, which provides relief from dandruff and improves scalp health
*Function as keratolytic, anti-inflammatory, anti-seborrheic and degreasing agent hence provides relief from dandruff symptoms like irritation, itching and flaking.
*Helps in normalization of ultra-structure of epidermal layer cells.
*High lipid solubility provides better efficacy.
*Effective distribution and deposition over scalp due to customized particle size.
*Effective against odour causing bacteria on the skin
*Used in various rinse-off and leave-on hair & skin care products
*Available as easy to add aqueous fine particle suspension providing formulation feasibility & stability
*Available in different particle size range, viscosity modifiers and preservative systems.
*Excellent compatibility with surfactants and alkaline cosmetic formulations.



ALTERNATIVES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
*KETOCONAZOLE,
*SELENIUM SULFIDE



SAFETY PROFILE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
While generally safe for topical use, Zinc Pyrithione 48% aqueous dispersion may cause mild side effects such as skin irritation, redness, or dryness, especially in individuals with sensitive skin.
Prolonged or excessive use can exacerbate these symptoms.
Additionally, some people may experience allergic reactions characterized by itching or swelling.
Zinc Pyrithione 48% aqueous dispersion is advisable to perform a patch test before widespread application and discontinue use if adverse reactions occur.



ORIGIN OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is synthesized through a multistep chemical process.
Initially, 2-mercaptopyridine-N-oxide reacts with sodium hydroxide to form sodium pyrithione.
Zinc Pyrithione 48% aqueous dispersion undergoes a double displacement reaction with zinc sulfate, yielding Zinc Pyrithione precipitate.
Zinc Pyrithione 48% aqueous dispersion is then filtered, washed, and dried to obtain a fine powder.



APPEARANCE OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is a milky white suspension
Zinc Pyrithione 48% aqueous dispersion is also used as an antibacterial treatment for household sponges, most notably by the 3M Corporation.



FUNCTION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is best known for its use in treating dandruff and seborrhoeic dermatitis.



WHAT DOES ZINC PYRITHIONE 48% AQUEOUS DISPERSION DO IN A FORMULATION?
*Antidandruff
*Antimicrobial
*Hair conditioning
*Preservative



PREPARATION OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Method 1:
The principle of preparation is that ZnSO4•7H2O reacts with SPT to produce Zinc Pyrithione 48% aqueous dispersion and sodium sulfate.

Weigh the appropriate amount of zinc sulfate heptahydrate and prepare 0.25 mol/L and 0.50 mol/L of zinc sulfate solution, respectively.
The sodium pyridine-thione solution was measured and designed as 0.5 mo l/L and 1.0 mol/L of sodium pyridine-thione solution, respectively.
The reaction process conditions were controlled, and the two were quickly added into the three-necked flask separately in a certain volume ratio to obtain
Zinc Pyrithione 48% aqueous dispersion crystals, which were then filtered and washed.
Vacuum-dried to obtain Zinc Pyrithione 48% aqueous dispersion.


Method 2:
Pyridine was used as raw material.
After 30% H2O2 oxidation, N-oxidized-2-hydroxy pyridine was synthesized in dimethyl sulfoxide, toluene, and sulfur powder and combined with Zn2+ to form a salt.
Although this method is simple, easy to obtain raw materials, and cheap, the yield is meager, only about 17%.


Method 3:
Using 2-carboxy pyridine as raw material, the reaction conditions are relatively harsh, and catalysts such as NaH and LiCl are used in the reaction process, which is expensive and dangerous, making large-scale industrialization difficult.


Method 4:
Using 2-chloropyridine as raw material, a catalytic oxidation system consisting of maleic anhydride and acetic acid was used.
A Na2S-NaSH buffer system further controlled the sulfhydration reaction to obtain Zinc Pyrithione 48% aqueous dispersion with a yield of about 75%.



SHAMPOO ZINC PYRITHIONE 48% AQUEOUS DISPERSION MARKET: OVERVIEW
Zinc Pyrithione 48% aqueous dispersion, also called dandruff, is an antibacterial, antimicrobial, and antifungal substance that can be used to treat psoriasis of the scalp, acne, and seborrheic dermatitis.
Yeast growth, a major contributor to dandruff, can be inhibited by it.

Zinc Pyrithione 48% aqueous dispersion, as its name suggests, is formed from the chemical element zinc and is utilized in a number of hair and skin care products.
Many popular anti-dandruff shampoos contain Zinc Pyrithione 48% aqueous dispersion shampoo.
Zinc Pyrithione 48% aqueous dispersion is fungus, bacteria, and germs that can cause an itchy, flaky scalp can be killed by its antifungal, antibacterial, and antimicrobial properties.



PROPERTIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
In the crystalline state, Zinc Pyrithione 48% aqueous dispersion exists as a centrosymmetric dime, where each zinc is bonded to two sulfur and three oxygen centers.
The pyrithione ligands, formally monoanionic, are chelated to Zn2+ via oxygen and sulfur centers.
In solution, however, the dimers dissociate via the scission of one Zn-O bond.
Pyrithione is the conjugate base derived from 2-mercapto pyridine-N-oxide, a derivative of pyridine-N-oxide.



KEY PRODUCT ATTRIBUTES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
– Relieves flaking symptoms of dandruff
– Targets scalp with a slow release for highest efficacy
– Effective dispersion because it is not soluble
– Enhances substantivity to the skin and hair
– Maintains efficacy over long-term use without resistance



BENEFITS AND USES OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is highly effective, keeping in mind that it is gentle and mild on the skin.
Many anti-dandruff shampoos contain Zinc Pyrithione, 48% Aqueous Dispersion.

Zinc Pyrithione, 48% Aqueous Dispersion is antifungal, antibacterial, and antimicrobial, which means it can fight fungus, bacteria, and germs that cause itchy, flaky skin on the scalp.

Zinc Pyrithione, 48% Aqueous Dispersion cream is used to treat psoriasis and seborrheic dermatitis also called dandruff.
Face washes containing Zinc Pyrithione, 48% Aqueous Dispersion can help relieve the redness and irritation caused by seborrheic dermatitis on the face.
Zinc Pyrithione, 48% Aqueous Dispersion can also assist with the greasiness that comes with eczema and seborrheic dermatitis.



WHAT IS ZINC PYRITHIONE, 48% AQUEOUS DISPERSION, AND WHAT IS ZINC PYRITHIONE, 48% AQUEOUS DISPERSION USED FOR?
Zinc Pyrithione, 48% Aqueous Dispersion is a chemical compound with antifungal and antimicrobial properties, used to treat seborrheic dermatitis and dandruff.
Seborrheic dermatitis is believed to result from an inflammatory skin reaction to the overgrowth of Malessezia yeast that commonly lives on the skin surface.

Seborrheic dermatitis causes redness, itching, and skin flaking, including dandruff on the scalp.
Zinc Pyrithione, 48% Aqueous Dispersion is also used off-label to treat tinea versicolor, another fungal skin infection.
Zinc Pyrithione, 48% Aqueous Dispersion is commonly used as the main active ingredient in anti-dandruff shampoos, conditioners, soaps, lotions, and creams available over the counter (OTC).

Zinc Pyrithione, 48% Aqueous Dispersion inhibits yeast growth by increasing the cellular levels of copper and damaging iron-sulfur clusters of proteins that are essential for fungal metabolism and growth.
Zinc Pyrithione, 48% Aqueous Dispersion has a broad spectrum of activity against organisms including fungi, and gram-positive and gram-negative bacteria.



BACTERICIDAL MECHANISM OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Pyrithione acts on bacterial cells.
The bactericidal mechanism of Zinc Pyrithione 48% aqueous dispersion varies slightly under different acidic and alkaline conditions.

Under neutral or acidic conditions, pyrithione takes K+ out of the bacterial cell and H+ into the bacterial cell.
Under alkaline conditions, pyrithione takes K+ or Mg2+ out of the bacterial cell and Na+ into the bacterial cell.

By eliminating the ionic gradient for the bacteria to obtain nutrients, the cells are eventually “starved”.
Therefore, the bactericidal mechanism of Zinc Pyrithione 48% aqueous dispersion is not the same as that of many bactericides, as it kills bacteria without being consumed.



GENERAL PROPERTIES OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion Antimicrobial:
– Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent
– Zinc Pyrithione 48% aqueous dispersion inhibits the growth of a broad spectrum of both Gram positive and Gram negative bacteria
– Zinc Pyrithione 48% aqueous dispersion inhibits the growth of fungi, both yeast and mold
– Zinc Pyrithione 48% aqueous dispersion inhibits the growth of algae



KEY PRODUCT ATTRIBUTES FOR ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion relieves flaking symptoms of dandruff
Zinc Pyrithione 48% aqueous dispersion targets scalp with a slow release for highest efficacy
Effective dispersion because Zinc Pyrithione 48% aqueous dispersion is not soluble
Zinc Pyrithione 48% aqueous dispersion enhances substantivity to the skin and hair
Zinc Pyrithione 48% aqueous dispersion maintains efficacy over long-term use without resistance



GENERAL PROPERTIES AND APPLICATIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is a mixture in water of very fine particles of zinc pyrithione, a dispersant, and a viscosity control agent.
Zinc Pyrithione 48% aqueous dispersion is an effective antidandruff agent.
Zinc Pyrithione 48% aqueous dispersion is the growth of a broad spectrum of both Gram positive and Gram negative bacteria.
Zinc Pyrithione 48% aqueous dispersion inhibits the growth of fungi, both yeast and mold.
Zinc Pyrithione 48% aqueous dispersion inhibits the growth of algae.



WHAT IS ZINC PYRITHIONE, 48% AQUEOUS DISPERSION USED FOR AND HOW DOES ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORK?
Zinc Pyrithione, 48% Aqueous Dispersion is an over-the-counter (OTC) product used to treat dandruff (seborrhea).



HOW ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORKS?
Zinc Pyrithione, 48% Aqueous Dispersion works by inhibiting the growth of yeast, which is the main factor in dandruff.
Zinc Pyrithione, 48% Aqueous Dispersion works by supplying moisture to the skin and scalp, thereby hydrating them.



CONCENTRATION AND SOLUBILITY OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is recommended that it be used at a concentration of 0.5 to 1% for best results.
Zinc Pyrithione, 48% Aqueous Dispersion is soluble in water and alcohol but insoluble in volatile oils.



HOW TO USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Mix Zinc Pyrithione, 48% Aqueous Dispersion with water in the recommended concentration and stir until a homogeneous mixture is created.
Add other surfactants and enhancing ingredients like essential oils, depending on your product and need, and mix properly.
Add this mixture to the warm base of the product and stir until the desired thickness and texture are obtained.



CHEMICAL INCOMPATIBILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Transchelation occurs in the presence of heavy metal ions.
Even traces of the corresponding chelates can cause a noticeable discoloration, foremost the iron and copper complexes.
Zinc Pyrithione 48% aqueous dispersion is sensitive to strong oxidizing and reducing agents.

The Conductivity of water should be less than 5μs/cm Calculate the dosage to ensure that whole barrels of product would be added for each batch.
It is recommended to add a little zinc salt to the water to ovoid occurring Fe(III) complexes when the conductivity of the water is less than 20μs/cm.
Zinc Pyrithione 48% aqueous dispersion is incompatible with EDTA, which, however, does no harm the sterilizing effect of Zinc pyrithione



TYPE OF INGREDIENT OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
*Antifungal,
*antimicrobial,
*antibacterial properties



MAIN BENEFITS OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Treats dandruff, soothes scalp irritation, regulates oil production, and prevents itching.



WHO SHOULD USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is best for those experiencing dandruff or seborrheic dermatitis, which may be associated with an oily scalp.
It is best to consult a dermatologist to determine the cause of your scalp flakes or irritation before using Zinc Pyrithione, 48% Aqueous Dispersion.



HOW OFTEN CAN YOU USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Shampoos containing Zinc Pyrithione, 48% Aqueous Dispersion can be used daily, and those individuals dealing with seborrheic dermatitis or dandruff are often advised to cleanse daily.
If the scalp is dry, it is okay to use a Zinc Pyrithione, 48% Aqueous Dispersion shampoo two to three days per week and a non-medicated shampoo on alternating days.



STABILITY OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion remains stable for 120 hours at 100℃, decomposes at 240℃。
Zinc Pyrithione 48% aqueous dispersion is sensitive to light and remains stable in pigmented coatings.
Zinc Pyrithione 48% aqueous dispersion is hydrolytically stable between pH 4.5 and 9.5.
Below pH 4.5 conversion to pyrithione occurs.
In alkaline solutions (pH > 9.5) conversion to soluble alkali salts occurs.



PRECAUTIONS OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Stores Zinc Pyrithione 48% aqueous dispersion in original container in a dry and cool area away from direct sunlight with temperature between 10℃ and 54℃.
Keep the Zinc Pyrithione 48% aqueous dispersion container tightly closed and sealed until ready for use.

Containers opened must be carefully resealed and kept upright to prevent leakage.
Agitate the barrels every 6 weeks.
Pre-agitate for at least 10 minutes before using.

May be pre-dispersed by a certain amount of water to assure better dispersion.
Calculate the dosage to ensure that whole barrels of the product are added for each batch.



PRODUCT BACKGROUND OF ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Zinc Pyrithione 48% aqueous dispersion is the most popular anti-dandruff ingredient in the world, offering bactericide-fungicide efficacy in shampoos, conditioners and leave-on products.



PROPERTIES OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Zinc Pyrithione, 48% Aqueous Dispersion is a clarifying shampoo for dry & dandruff-prone hair.
-Effectively cleanses & purifies hair.
Zinc Pyrithione, 48% Aqueous Dispersion helps eliminate itching & controls dandruff while visibly reducing flakes and leaves hair fresh & healthy-looking.

It contains Zinc Pyrithione, 48% Aqueous Dispersion – an active ingredient with antifungal and antibacterial properties, which intensely improves the scalp condition.
Zinc Pyrithione, 48% Aqueous Dispersion combats dandruff, seborrhoea and other undesirable changes.
In addition, bisabolol has antiseptic and anti-inflammatory properties, which soothe and restore comfort.



HOW TO USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION:
Apply Zinc Pyrithione, 48% Aqueous Dispersion to wet hair and massage in.
Rinse thoroughly.
If necessary, repeat the process.
Use Zinc Pyrithione, 48% Aqueous Dispersion daily or as special treatment.



ZINC PYRITHIONE, 48% AQUEOUS DISPERSION IN TOPICAL TREATMENTS:
Zinc Pyrithione, 48% Aqueous Dispersion is an antifungal and antibacterial agent.
That’s what makes Zinc Pyrithione, 48% Aqueous Dispersion so powerful at fighting dandruff — more on that later.
Here are some of the highlights when it comes to using Zinc Pyrithione, 48% Aqueous Dispersion in topical treatments.

*Low Solubility:
A key element of Zinc Pyrithione, 48% Aqueous Dispersion’s power is that it has relatively low solubility, meaning it has staying power on our skin.
Zinc Pyrithione, 48% Aqueous Dispersion stays on our scalps, even after we’ve rinsed our hair of shampoo so that it can continue to fight fungus.

*Safe For Topical Use:
Most importantly, Zinc Pyrithione, 48% Aqueous Dispersion is proven to be a safe agent to introduce to our skin.
Thankfully, Zinc Pyrithione, 48% Aqueous Dispersion has been approved by the FDA as a safe and effective treatment for dandruff for over 60 years.



ZINC PYRITHIONE, 48% AQUEOUS DISPERSION WORKS WELL WITH:
Selenium sulfide, another ingredient commonly found in dandruff shampoos stronger than Zinc Pyrithione, 48% Aqueous Dispersion.
Additionally, some individuals may alternate with other Zinc Pyrithione, 48% Aqueous Dispersion ingredients, such as ketoconazole, an antifungal ingredient.



DON’T USE WITH:
There are no known ingredients that negatively interfere with Zinc Pyrithione, 48% Aqueous Dispersion; however, it is advised that you speak to a medical professional before using if you are pregnant or nursing.



WHAT HAIR TYPES CAN USE ZINC PYRITHIONE, 48% AQUEOUS DISPERSION?
Our experts agree that Zinc Pyrithione, 48% Aqueous Dispersion is safe for all hair types but would be most beneficial for those experiencing dandruff, seborrheic dermatitis, or other scalp conditions that are aggravated by fungus/yeast.
Some formulations of shampoos and topical scalp products include Zinc Pyrithione, 48% Aqueous Dispersion and hydrating and moisturizing ingredients that would be better for those with dry or color-treated hair.

If you don't have dandruff or other scalp conditions, skipping the products with Zinc Pyrithione, 48% Aqueous Dispersion is best.
The only downside is that Zinc Pyrithione, 48% Aqueous Dispersion could ultimately dry out the hair and scalp slightly and upset a healthier scalp microbiome if there is no dandruff or inflammation.

Zinc Pyrithione, 48% Aqueous Dispersion is always best to speak with a medical professional to evaluate the scalp and determine the best course of treatment.

For those with dry or sensitive skin, it is best to slowly incorporate Zinc Pyrithione, 48% Aqueous Dispersion into a routine and use caution as some dryness and irritation may occur, Garshick explains.
Engelman cautions that it is best to speak to a medical professional if you are pregnant or nursing before using Zinc Pyrithione, 48% Aqueous Dispersion.



BENEFITS OF ZINC PYRITHIONE, 48% AQUEOUS DISPERSION FOR HAIR:
The benefits of Zinc Pyrithione, 48% Aqueous Dispersion extend beyond the skin of the scalp.
By improving the health of the scalp, the health of the hair benefits as well.

Zinc Pyrithione, 48% Aqueous Dispersion has the power to treat a variety of issues, including dandruff, itchiness, acne, and scalp psoriasis by targeting the yeast/fungus that is causing the problem.


*Zinc Pyrithione, 48% Aqueous Dispersion fights dandruff-causing fungus:
The antifungal, antimicrobial, and antibacterial properties stop dandruff at its source.
Zinc Pyrithione, 48% Aqueous Dispersion is naturally anti-inflammatory and is also antifungal and antibacterial.

Since dandruff is caused directly by an excessive amount of fungus and yeast living on the scalp, by adding the Zinc Pyrithione, 48% Aqueous Dispersion, you decrease the fungal buildup on the scalp and alleviate the inflammation causing the dandruff.


*Zinc Pyrithione, 48% Aqueous Dispersion prevents itching:
Dandruff is one of the leading causes of scalp itchiness.
By preventing dandruff and eliminating the irritating yeast/fungus that causes it, Zinc Pyrithione, 48% Aqueous Dispersion provides itch relief quickly.


*Zinc Pyrithione, 48% Aqueous Dispersion regulates oil production:
Zinc Pyrithione, 48% Aqueous Dispersion can control the oil production and dandruff often found in those with seborrheic dermatitis.


*Zinc Pyrithione, 48% Aqueous Dispersion improves overall scalp health:
Dandruff disrupts the health of the scalp by clogging follicles with flakes and by causing inflammation and irritation.
Zinc Pyrithione, 48% Aqueous Dispersion is able to improve the overall health of the scalp by preventing and treating dandruff.


*Zinc Pyrithione, 48% Aqueous Dispersion promotes hair growth:
Zinc Pyrithione, 48% Aqueous Dispersion has the potential to impact hair growth.

Since a number of thinning hair and hair loss concerns are related to the scalp, Zinc Pyrithione, 48% Aqueous Dispersion can help clear dead skin cells or conditions that prevent hair growth (clogged hair follicles, psoriasis, etc.) and thus promote fuller, healthier hair.

Garshick agrees and points out a study that showed that daily use of 1 percent Zinc Pyrithione, 48% Aqueous Dispersion shampoo over 26 weeks showed an improvement in hair growth.


*Zinc Pyrithione, 48% Aqueous Dispersion improves overall appearance of hair:
The overall appearance of the hair is heavily influenced by the oiliness of the scalp and the thickness of the hair.
By regulating oil production and encouraging new growth, Zinc Pyrithione, 48% Aqueous Dispersion can boost the overall appearance of the hair.



PHYSICAL and CHEMICAL PROPERTIES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0

Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available

Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available

Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2
Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų

Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314

HScode: 2933399010
Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble

Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.
Appearance: Off white to white dispersion
Zinc pyrithione (%): 48-50
Zinc(%): 9.3-11.3
pH(5%): 6.5-8.5

Appearance:Aqueous Suspension of White or Creamy Color
Assay, %: 48.0~50.0
Zinc, % :9.3~11.3
pH: 6.5~8.0
Particle size: D90,μm≤0.5
Particle size: D100,μm ≤1.5
Heavy metals(as Pb),: ppm≤20
Aerobic Plate Count,: <100cfu/g
CAS No.: 13463-41-7
UN No.: 2811
Molecular Formula: C10H8N2O2S2Zn
InChIKeys: InChIKey=PICXIOQBANWBIZ-UHFFFAOYSA-N
Molecular Weight: 317.69300
Exact Mass: 315.93200
UN Number: 2811
DSSTox ID: DTXSID7026314
HScode: 2933399010

Product Name: Pyrithione zinc
CAS No.: 13463-41-7
PSA: 101.52000
XLogP3: 3.34050
Appearance: Off-white to tan powder
Density: 1.782 g/cm3 @ Temp: 25 °C
Melting Point: 240 °C (decomp)
Boiling Point: 253.8ºC at 760 mmHg
Flash Point: 107.3ºC
Water Solubility: H2O: insoluble
Storage Conditions: Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Vapor Pressure: 0.00275mmHg at 25°C
Air and Water Reactions: Insoluble in water.
Reactive Group: Salts, Basic
Reactivity Profile:
ZINC PYRITHIONE is a coordination compound where zinc is chelated
by oxygen and sulfur donor atoms on the pyrithione ligand.
It is a basic salt.

Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 73 mN/m at 20 °C
CAS No: 13463-41-7
Molecular Formula: C10H8N2O2S2Zn
Molecular Weight: 362.08
Appearance: White Powder
Boiling Point: 350.20°C
Melting Point: 240°C
Solubility: Soluble in water
Viscosity: Low to moderate
Molecular Weight: 317.7 g/mol
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 4
Rotatable Bond Count: 2

Exact Mass: 315.931862 g/mol
Monoisotopic Mass: 315.931862 g/mol
Topological Polar Surface Area: 52.9Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 183
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
MELTING POINT: ≥240℃
PH(5%solution):6.5-8.5
LOD :NMT 0.5%
Particle size :D70
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Appearance: White powder
Assay, %: ≥98.0
Melting Point, ℃: ≥240
D50, μm: ≤5
D90, μm: ≤10
pH: 6.0~9.0
Loss on drying, %: ≤0.5
Physical state: powder
Color: beige
Odor: odorless
Melting point/freezing point
Melting point/range: 267 °C

Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: 0,00493 g/l at 20 °C
Partition coefficient: n-octanol/water:
log Pow: 0,9 at 25 °C
Vapor pressure: No data available
Density: 1,76 g/cm3 at 20,1 °C
Relative density: No data available

Chemical Name: Zinc pyrithione
CAS: 13463-41-7
Molecular Fomula: C10H8N2O2S2Zn
Molecular Weight: 317.7
Appearance: White latex(48%), White to slight yellow powder(98%)
Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
CAS No:13463-41-7
Other Names:Zinc pyrithione
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)

Melting point:262
Boiling Point:253.8C at 760 mmHg
flash point:107.3C
PSA:101.52000
logP:3.34050
Solubility:Insoluble (Chemical formula: C10H8N2O2S2Zn
Molar mass: 317.70 g/mol
Appearance: colourless solid
Melting point: 240 °C (464 °F; 513 K) (decomposition)
Boiling point: decomposes
Solubility in water: 8 ppm (pH 7)
MF:C10H8N2O2S2Zn
EINECS No:236-671-3
Density:1.782 (25 C)
Melting point:262



FIRST AID MEASURES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system



EXPOSURE CONTROLS/PERSONAL PROTECTION of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store at Room Temperature.



STABILITY and REACTIVITY of ZINC PYRITHIONE 48% AQUEOUS DISPERSION:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ZINC RICINOLEATE
ZINC SALICYLATE N° CAS : 16283-36-6 Nom INCI : ZINC SALICYLATE Nom chimique : Zinc Disalicylate N° EINECS/ELINCS : 240-380-7 Classification : Règlementé Restriction en Europe : III/24 Ses fonctions (INCI) Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes
ZINC STEARATE

Zinc stearate is a chemical compound that falls under the category of metal salts or metallic stearates.
Zinc stearate is formed by the reaction of stearic acid (a long-chain fatty acid) with zinc oxide.
The resulting compound, zinc stearate, is a white, finely divided powder that is insoluble in water but dispersible in organic solvents.

CAS Number: 557-05-1



APPLICATIONS


Zinc stearate is commonly used as a mold release agent in the plastics industry to facilitate the smooth ejection of plastic parts from molds.
In the rubber industry, it serves as a lubricant and anti-tack agent during the processing of rubber compounds, preventing adhesion between rubber layers.
Zinc stearate is added to PVC (polyvinyl chloride) formulations to enhance the resin's flow properties and improve its processability.
Zinc stearate acts as a flow aid and anti-caking agent in powdered products, including cosmetics, pharmaceuticals, and food items, to prevent clumping and ensure even distribution.

In the cosmetics industry, zinc stearate is used in eyeshadows, foundations, and face powders to provide a silky texture and improve blendability.
Zinc stearate contributes to the matte finish in makeup products, helping control shine and oiliness on the skin.
Zinc stearate is employed in the formulation of pressed powders and compact cosmetics due to its binding properties.

Zinc stearate finds application in pharmaceutical tablet manufacturing as a tablet binder, aiding in the compression of powders into solid tablets.
Zinc stearate is used as a lubricant in the production of abrasive products like grinding wheels and sandpaper.
In the paint and coatings industry, zinc stearate functions as an anti-settling agent, preventing pigment settling in paint formulations.

Zinc stearate is added to ink formulations to improve flow characteristics and prevent ink transfer issues in printing processes.
Zinc stearate is utilized in the manufacture of crayons and colored pencils to enhance color dispersion and texture.
In the ceramics industry, it is used as a glazing agent to reduce friction and enhance surface finish.

Zinc stearate is an effective anti-blocking agent in the production of plastic films, preventing them from sticking together.
Zinc stearate serves as a processing aid in the extrusion and injection molding of thermoplastics, ensuring smooth processing and uniform product quality.
Zinc stearate can be found in the production of adhesive tapes to improve release properties from the roll.

Zinc stearate is added to latex gloves to prevent sticking and adhesion during manufacturing and packaging.
Zinc stearate is employed in the manufacturing of automotive weatherstripping to enhance flexibility and reduce friction.
In the construction industry, zinc stearate is used as a lubricant in the production of concrete pipe gaskets.

Zinc stearate acts as a desensitizing agent in the manufacture of explosives, reducing sensitivity to friction and impact.
Zinc stearate is utilized in the formulation of thermosetting resins to enhance their processing and handling.
In the foundry industry, it is added to sand cores to improve flowability and reduce defects in castings.
Zinc stearate finds application in the production of polishing compounds for metal, plastic, and glass surfaces.

In the textile industry, it is used as a lubricant in the spinning of synthetic fibers to prevent static and improve fiber handling.
Zinc stearate's diverse applications span multiple industries, making it a valuable and versatile chemical compound for enhancing manufacturing processes and product quality.
In the ceramics and pottery industry, zinc stearate is utilized as a glaze ingredient to control the flow and adhesion of glaze materials during firing.
Zinc stearate is used in the production of printing inks, especially in offset and gravure printing, to improve ink transfer and prevent ink set-off onto adjacent sheets.

Zinc stearate acts as a matting agent in the paint and coating industry, providing a matte finish to paints and coatings.
In the plastics compounding process, it functions as a processing aid to improve the extrusion and molding of plastic products.

Zinc stearate is added to rubber products such as tires and conveyor belts to enhance their processing and reduce friction during manufacturing.
In the paper and paperboard industry, zinc stearate is used as a lubricant and release agent in the production of coated paper.
Zinc stearate serves as a dusting powder in the manufacturing of latex products like gloves and balloons to prevent sticking.

Zinc stearate is employed as a flatting agent in the woodworking industry to reduce glossiness and enhance the finish of wood coatings.
Zinc stearate acts as an anti-blocking agent in the production of plastic bags and films to prevent them from sticking together.
In the pharmaceutical industry, it is used in tablet pressing to improve the flowability and compressibility of tablet formulations.

Zinc stearate is found in the production of thermoplastic elastomers (TPEs) to enhance their processing and mold release properties.
Zinc stearate serves as a lubricant in the manufacture of PVC pipes and fittings to facilitate extrusion and prevent fusion.
Zinc stearate is added to polyolefin films to reduce the coefficient of friction and improve slip properties.

In the textile and fiber industry, zinc stearate is used in spinning processes to reduce static electricity and improve fiber handling.
Zinc stearate is employed as a lubricant and anti-tack agent in the production of latex foam products like mattresses and cushions.
Zinc stearate can be found in the production of automotive and industrial gaskets to improve their handling and installation.
Zinc stearate functions as a release agent in the production of rubber gloves, ensuring easy removal from molds.

Zinc stearate is used as a gloss control agent in the manufacturing of paper coatings and varnishes.
In the foundry industry, it is added to core sand formulations to improve the flowability and release of sand cores.
Zinc stearate is utilized in the production of candles to prevent sticking to molds and enhance burn quality.
Zinc stearate is added to clay bodies in pottery and ceramics to reduce cracking and improve workability.

In the leather and footwear industry, it is used as a lubricant during leather processing and shoe sole production.
Zinc stearate is an essential component in the manufacturing of firework compositions to prevent premature ignition.

Zinc stearate serves as an anti-dusting agent in the production of fertilizer granules to reduce dust formation during handling.
Zinc stearate's versatility and multifunctional properties make it an integral part of various manufacturing processes across industries, contributing to product quality and efficiency.
In the ceramics and pottery industry, zinc stearate is utilized as a glaze ingredient to control the flow and adhesion of glaze materials during firing.

Zinc stearate is used in the production of printing inks, especially in offset and gravure printing, to improve ink transfer and prevent ink set-off onto adjacent sheets.
Zinc stearate acts as a matting agent in the paint and coating industry, providing a matte finish to paints and coatings.
In the plastics compounding process, it functions as a processing aid to improve the extrusion and molding of plastic products.

Zinc stearate is added to rubber products such as tires and conveyor belts to enhance their processing and reduce friction during manufacturing.
In the paper and paperboard industry, zinc stearate is used as a lubricant and release agent in the production of coated paper.
Zinc stearate serves as a dusting powder in the manufacturing of latex products like gloves and balloons to prevent sticking.

Zinc stearate is employed as a flatting agent in the woodworking industry to reduce glossiness and enhance the finish of wood coatings.
Zinc stearate acts as an anti-blocking agent in the production of plastic bags and films to prevent them from sticking together.
In the pharmaceutical industry, it is used in tablet pressing to improve the flowability and compressibility of tablet formulations.
Zinc stearate is found in the production of thermoplastic elastomers (TPEs) to enhance their processing and mold release properties.
Zinc stearate serves as a lubricant in the manufacture of PVC pipes and fittings to facilitate extrusion and prevent fusion.

Zinc stearate is added to polyolefin films to reduce the coefficient of friction and improve slip properties.
In the textile and fiber industry, zinc stearate is used in spinning processes to reduce static electricity and improve fiber handling.
Zinc stearate is employed as a lubricant and anti-tack agent in the production of latex foam products like mattresses and cushions.
Zinc stearate can be found in the production of automotive and industrial gaskets to improve their handling and installation.
Zinc stearate functions as a release agent in the production of rubber gloves, ensuring easy removal from molds.

Zinc stearate is used as a gloss control agent in the manufacturing of paper coatings and varnishes.
In the foundry industry, it is added to core sand formulations to improve the flowability and release of sand cores.
Zinc stearate is utilized in the production of candles to prevent sticking to molds and enhance burn quality.
Zinc stearate is added to clay bodies in pottery and ceramics to reduce cracking and improve workability.

In the leather and footwear industry, it is used as a lubricant during leather processing and shoe sole production.
Zinc stearate is an essential component in the manufacturing of firework compositions to prevent premature ignition.

Zinc stearate serves as an anti-dusting agent in the production of fertilizer granules to reduce dust formation during handling.
Zinc stearate's versatility and multifunctional properties make it an integral part of various manufacturing processes across industries, contributing to product quality and efficiency.
In the manufacturing of fiberglass-reinforced plastics (FRP), zinc stearate is used as a release agent to aid in the demolding of FRP components.

Zinc stearate plays a role in the production of ceramics and porcelain by acting as a lubricant during shaping and forming processes.
In the cosmetics industry, zinc stearate is added to lipstick formulations to improve texture, reduce shine, and enhance color dispersion.
Zinc stearate is used as a lubricant in the manufacturing of lead-acid batteries, aiding in the plate assembly process.

Zinc stearate finds application in the production of automotive parts, such as gaskets and seals, to reduce friction and improve sealing properties.
In the woodworking industry, it is utilized as a sanding aid to prevent clogging of sandpaper during the sanding of wood surfaces.
Zinc stearate is added to printing ink formulations for flexographic and letterpress printing to enhance ink transfer onto substrates.
In the production of PVC flooring and tiles, zinc stearate is used as a processing aid to improve workability and mold release.
Zinc stearate is found in the formulation of deodorant and antiperspirant products to improve texture and reduce greasiness.

Zinc stearate serves as a release agent for the production of rubber rollers used in various industrial applications.
In the creation of 3D printing filaments, it helps improve filament flow properties and prevent nozzle clogging.

Zinc stearate is used as a slip agent in the production of plastic film and sheeting to facilitate winding and unwinding processes.
Zinc stearate can be found in the manufacture of thermal transfer ribbons for barcode and label printing.
Zinc stearate is used as a dusting agent in the production of chewing gum to prevent sticking during processing and packaging.
In the construction industry, zinc stearate is added to cement-based products to reduce water absorption and improve workability.

Zinc stearate is employed in the formulation of graphite lubricants for use in locks, hinges, and mechanical components.
Zinc stearate is added to crayon formulations to enhance color blending and reduce smudging.
In the casting of metal and aluminum parts, it serves as a mold release agent to facilitate part removal.
The compound finds use in the production of foamed plastics, such as PVC foam boards, to improve expansion and cell structure.

Zinc stearate is added to rubber compounds used in the manufacturing of conveyor belts to enhance flexibility and reduce wear.
Zinc stearate is used as an anti-foaming agent in the production of latex paints and coatings.
Zinc stearate is added to ceramic glazes to control the thickness of glaze layers and improve application properties.
In the cosmetics industry, it is employed in the formulation of pressed powder compacts for ease of application.

Zinc stearate is used in the production of thermosetting resins to enhance moldability and surface finish.
Its widespread use in various industries underscores its importance as a versatile and effective additive that improves manufacturing processes and product quality.



DESCRIPTION


Zinc stearate is a chemical compound that falls under the category of metal salts or metallic stearates.
Zinc stearate is formed by the reaction of stearic acid (a long-chain fatty acid) with zinc oxide.
The resulting compound, zinc stearate, is a white, finely divided powder that is insoluble in water but dispersible in organic solvents.

Zinc stearate is commonly used in various industries, including the plastics, rubber, cosmetics, pharmaceuticals, and food industries, due to its unique properties.
Zinc stearate acts as a lubricant, release agent, and anti-caking agent. In the plastics and rubber industries, it is often used as a mold release agent to facilitate the release of molded products from molds.
In cosmetics and pharmaceuticals, it is used as a binding agent in the production of tablets and powders, as well as in makeup and skincare products to improve texture and consistency.

Zinc stearate is a white, odorless, and fine-textured powder.
Zinc stearate is a chemical compound formed from the reaction of stearic acid and zinc oxide.
Zinc stearate is insoluble in water but dispersible in organic solvents.

Zinc stearate is widely used as a versatile industrial chemical.
Zinc stearate is known for its lubricating properties, making it an effective mold release agent in plastics and rubber manufacturing.

Due to its lubricity, it helps prevent sticking and facilitates the easy removal of molded products from molds.
Zinc stearate has a low melting point, which aids in its application as a mold release agent.
Zinc stearate is non-toxic and safe for various industrial and commercial uses.
Zinc stearate acts as an anti-caking agent in powdered products, preventing clumping and ensuring a free-flowing consistency.

In the cosmetics industry, zinc stearate is used in makeup formulations, such as face powders and eyeshadows, to improve texture and blendability.
Zinc stearate contributes to a silky and smooth feel in cosmetics, enhancing the application and finish of makeup products.
Zinc stearate can be found in pharmaceutical tablets and powders, where it serves as a binding agent and helps maintain tablet integrity.

Zinc stearate is used as a flow aid in the pharmaceutical industry to ensure uniform mixing of powders.
In the food industry, zinc stearate is employed as a release agent in the production of chewing gum to prevent sticking to manufacturing equipment.
Zinc stearate is chemically stable and does not react with most substances under normal conditions.

Zinc stearate has a low bulk density, making it suitable for applications where lightweight powders are desired.
Zinc stearate is compatible with a wide range of polymers, including polyethylene, polypropylene, and PVC, in plastics processing.
In the rubber industry, zinc stearate is added to rubber compounds to improve processing and prevent adhesion during mixing.



PROPERTIES


Chemical Formula: C36H70O4Zn
Molecular Weight: Approximately 632.33 g/mol
Appearance: Fine, white powder
Odor: Odorless
Solubility: Insoluble in water
Solubility in Organic Solvents: Soluble in common organic solvents such as alcohols, acetone, and chloroform.
Melting Point: Approximately 120-130°C (248-266°F)
Boiling Point: Decomposes before boiling
Density: Approximately 1.095 g/cm³
pH: Neutral
Flammability: Non-flammable
Refractive Index: 1.43 (approximate)
Particle Size: Typically in the micrometer range
Bulk Density: Varies depending on particle size and compaction



FIRST AID


Inhalation:

Move to Fresh Air:
If someone inhales airborne zinc stearate particles and experiences respiratory discomfort, move them to an area with fresh air immediately to allow for easier breathing.

Provide Oxygen:
If breathing difficulties persist or worsen, seek medical attention promptly.
In the meantime, if trained personnel are available and oxygen is accessible, provide oxygen to the affected person.


Skin Contact:

Remove Contaminated Clothing:
If zinc stearate comes into contact with the skin, remove contaminated clothing and shoes as quickly as possible to prevent further contact and contamination.

Wash Skin:
Wash the affected skin area gently but thoroughly with mild soap and lukewarm water for at least 15 minutes to remove any residual powder.
Avoid using hot water, as it may increase skin absorption.

Seek Medical Attention:
If skin irritation, redness, or rash develops or if there is any sign of an allergic reaction, seek medical attention promptly.


Eye Contact:

Flush Eyes:
If zinc stearate contacts the eyes, immediately flush the eyes with gently flowing, lukewarm water for at least 15 minutes.
Ensure that both eyes are thoroughly rinsed, holding the eyelids open to allow adequate flushing.

Remove Contact Lenses:
If applicable, remove contact lenses during the rinsing process if they can be easily removed.

Seek Medical Attention:
Even if there are no immediate symptoms, seek medical evaluation for eye exposure to ensure there is no damage or delayed effects.


Ingestion:

Do NOT Induce Vomiting:
If zinc stearate is ingested, do not induce vomiting.
Rinse the mouth and lips with water to remove any residual chemical.

Seek Medical Help:
Seek immediate medical attention or contact a poison control center.
Provide them with as much information as possible regarding the type and amount of exposure.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate personal protective equipment (PPE), including safety goggles or a face shield, chemical-resistant gloves, a lab coat or protective clothing, and chemical-resistant footwear when handling zinc stearate.
Ensure that PPE is in good condition and properly fitted.

Ventilation:
Use zinc stearate only in a well-ventilated area, such as a fume hood or with local exhaust ventilation.
Adequate ventilation helps to minimize exposure to airborne particles.

Avoid Inhalation:
Avoid inhaling airborne zinc stearate particles.
If airborne exposure is likely, wear a dust mask or respiratory protection as recommended by the safety data sheet (SDS) and local regulations.

Prevent Skin Contact:
Prevent direct skin contact with zinc stearate.
In case of contact, follow the first aid measures and safety procedures outlined in the SDS.

Eye Protection:
Wear safety goggles or a face shield to protect against potential eye contact.
In case of eye contact, follow the recommended first aid procedures.

Handling Equipment:
Use chemical-resistant equipment, including containers, pumps, and transfer hoses, when handling or transferring zinc stearate.
Ensure that all equipment is clean and in good working condition.

Avoid Open Flames and Sparks:
Although zinc stearate is non-flammable, avoid working near open flames, sparks, or other potential ignition sources.
Ensure that electrical equipment is suitable for use in hazardous areas.

Static Electricity:
Prevent the buildup of static electricity by using grounded containers and equipment.
Bond and ground containers before transferring or decanting zinc stearate to minimize the risk of static discharge.

Labeling:
Ensure that containers are properly labeled with the chemical name, hazard warnings, and safety information as required by regulations.


Storage:

Storage Area:
Store zinc stearate in a cool, dry, and well-ventilated storage area, away from direct sunlight and heat sources.
Keep it tightly sealed to prevent moisture absorption.

Temperature:
Store at a temperature below 25°C (77°F) to maintain product stability.
Avoid exposure to extreme temperatures.

Containers:
Use chemical-resistant containers made of materials compatible with zinc stearate, such as high-density polyethylene (HDPE) or glass.
Keep containers tightly closed when not in use.

Labeling:
Maintain clear and legible labels on storage containers, including the product name, hazard information, and storage instructions.

Separation:
Store zinc stearate away from incompatible materials, such as strong acids, strong bases, oxidizers, and reducing agents, to prevent chemical reactions or contamination.

Security:
Restrict access to authorized personnel only, and store zinc stearate away from areas with heavy foot traffic.

Inventory Control:
Keep an inventory record of the quantity of zinc stearate in storage, along with its usage and disposal information.

Regulatory Compliance:
Comply with local, state, and national regulations regarding the storage and handling of hazardous chemicals, including zinc stearate.

Emergency Equipment:
Ensure that emergency eyewash stations and safety showers are readily accessible in case of accidental exposure.

Spill Control:
Have spill control measures and materials (e.g., absorbents, spill kits) available in case of spills or leaks.



SYNONYMS


Zinc Octadecanoate
Zinc Stearate Technical
Octadecanoic Acid Zinc Salt
Zinc Distearate
Zinc Di(stearoyl)oxide
Stearic Acid Zinc Salt
Zinc(II) Octadecanoate
Zinc Bis(stearate)
Zinc(II) Stearate
Zinc(2+) Octadecanoate
Zinc Soap of Stearic Acid
Zinc(II) Octadecylate
Zinc Fatty Acid Salt
Zinc(II) 18-hydroxyoctadecanoate
Stearato de Zinc (Spanish)
Stéarate de Zinc (French)
Zinkstearat (German)
Stearato di Zinco (Italian)
Zinkstearaat (Dutch)
Zinkstearat (Swedish)
Zinc(2+) Stearate
Zinc Stearic Acid
Zinc Octadecylate
Zinc Fatty Acid
Zinc Palmitate Stearate
Zinc C18
Zinc Stearate Powder
Zinc Soap
Zinc Soap of Fatty Acid
Zinc Salt of Octadecanoic Acid
Zinc Salt of Stearic Acid
Zinc Salt of Palmitic Acid
Zinc(II) Octadecyl Hexadecanoate
Zinc(II) Octadecyl Palmitate
Zinc(II) Stearic Palmitic Acid
Zinc Octadecanoate Palmitate
Zinc Octadecanoate Octadecylate
Zinc Fatty Acid Soap
Zinc Octadecanoic Acid Ester
Zinc Stearate Ester
Zinc Soap of Octadecanoic Acid
Zinc Soap of Stearic Palmitic Acid
Zinc Octadecanoate Palmitate Stearate
Zinc(II) Octadecyl Stearate
Zinc Octadecanoate Palmitate Hexadecanoate
Zinc Octadecyl Stearate
Zinc Octadecanoate Palmitate Stearate
Zinc Soap of Octadecyl Palmitate
Zinc Soap of Hexadecanoic Acid
Zinc Stearate Palmitate
Zinc Stearate Palmitic Acid
Zinc Stearate Octadecylate
Zinc Stearate Octadecanoate Hexadecanoate
Zinc Palmitate Octadecylate
Zinc Palmitate Octadecanoate Stearate
Zinc Palmitate Stearate Octadecanoate
Zinc Hexadecanoate Octadecanoate
Zinc Octadecyl Palmitate Stearate
Zinc Octadecyl Palmitate Hexadecanoate
Zinc Octadecanoate Palmitate Stearate Hexadecanoate
Zinc Octadecanoate Palmitate Stearate Octadecylate
Zinc Octadecyl Hexadecanoate Palmitate Stearate
Zinc Octadecyl Hexadecanoate Palmitate
Zinc Octadecanoate Palmitate Stearate
Zinc Palmitate Stearate Octadecylate Hexadecanoate
Zinc Stearate Octadecyl Palmitate Hexadecanoate
Zinc Octadecyl Palmitate Octadecanoate
Zinc Octadecyl Hexadecanoate Palmitate Stearate Octadecanoate
Zinc Octadecyl Hexadecanoate Octadecanoate
Zinc Octadecyl Palmitate Stearate Octadecanoate Hexadecanoate