Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH.
Propan-1-ol (n-propanol) is miscible with water, ethanol and ether.
Propan-1-ol (n-propanol) is a colourless liquid and an isomer of 2-propanol.
CAS Number: 71-23-8
EC Number: 200-746-9
MDL Number: MFCD00002941
Molecular Formula: C3H8O / CH3CH2CH2OH
Propan-1-ol, n-Propyl alcohol, n-Propanol, n-PrOH, Ethyl carbinol, 1-Hydroxypropane, Propionic alcohol, Propionyl alcohol, Propionylol, Propyl alcohol, Propylic alcohol, Propylol, 1-propanol, propanol, Propan-1-ol, Propyl alcohol, n-propanol, 71-23-8, n-Propyl alcohol, ethylcarbinol, Policosanol,
optal, 1-hydroxypropane, osmosol extra, Propylic alcohol, Propanol-1, 1-Propyl alcohol, n-Propan-1-ol, Propanole, Propanolen, Alcohol, propyl,
Propanoli, Ethyl carbinol, Alcool propylique, Propylowy alkohol, n-Propyl alkohol, Albacol, 142583-61-7, propane-1-ol, 1-PROPONOL, propylalcohol, Propyl alcohol, normal Caswell No. 709A, FEMA No. 2928, FEMA Number 2928, Propyl alcohol (natural), Propyl alcohol, n-, Propyl-d7 alcohol, NSC 30300, CCRIS 3202, HSDB 115, n-Propylalkohol, EINECS 200-746-9, EPA Pesticide Chemical Code 047502, n-PrOH, UNII-96F264O9SV, BRN 1098242, DTXSID2021739, CHEBI:28831, AI3-16115, Propylan-propyl alcohol, 96F264O9SV, Propyl-1,1-d2 alcohol, MFCD00002941, NSC-30300, 62309-51-7, UN 1274, Propyl-3,3,3-d3 alcohol, DTXCID001739,
PROPANOL-2,2-D2, PROPYL ALCOHOL (PROPANOL), EC 200-746-9, 4-01-00-01413 (Beilstein Handbook Reference), 1-Propanol, anhydrous, 1-Propanol-D1, Propanol, Propan-1-ol, POL, Propanol, 1-, PROPANOL (EP MONOGRAPH), PROPANOL [EP MONOGRAPH], PROPYL ALCOHOL (MART.), PROPYL ALCOHOL [MART.], PROPYL-2-D1 ALCOHOL, 188894-71-5, 70907-80-1, 89603-83-8, 1 Propanol, UN1274, Hydroxypropane, ethyl methanol, n-propylalcohol, normal propanol, 3-propanol, nPrOH, HOPr, PrOH, normal propyl alcohol, Caswell No 709A, N-Propanol ACS grade, n-C3H7OH, 1-Propanol, HPLC Grade, bmse000446, N-PROPANOL [HSDB], PROPANOL [WHO-DD], 1-Propanol, >=99%, PROPYL ALCOHOL [MI], Pesticide Code: 047502, PROPYL ALCOHOL [FCC], WLN: Q3, CHEMBL14687, PROPYL ALCOHOL [FHFI], PROPYL ALCOHOL [INCI], 1-PROPANOL [USP-RS], 1-Propanol, analytical standard, 1-Propanol, JIS special grade, 1-Propanol, >=99%, FG, 1-Propanol, LR, >=99%, 1-Propanol, >=99.80%, BDBM36153, 1-Propanol, anhydrous, 99.7%, 1-Propanol, p.a., 99.5%, 1-Propanol, AR, >=99.5%, AMY11110, NSC30300, Tox21_302440, 1-Propanol, Spectrophotometric Grade, LMFA05000101, n-Propanol or propyl alcohol, normal, 1-Propanol, natural, >=98%, FG, Hydroxypropyl cellulose-SL (HPC-SL), 1-Propanol, >=99% (GC), purum, AKOS000249219, 1-Propanol, for HPLC, >=99.5%, 1-Propanol, for HPLC, >=99.9%, DB03175, 1-Propanol, ACS reagent, >=99.5%, 1-Propanol, HPLC grade, >=99.5%, CAS-71-23-8, 1-Propanol, purum, >=99.0% (GC), NCGC00255163-01, 1-Propanol 100 microg/mL in Acetonitrile, PROPYL-1,1,3,3,3-D5 ALCOHOL, 1-Propanol, SAJ first grade, >=99.0%, FT-0608280, FT-0608281, FT-0627482, NS00001811, P0491, 1-Propanol, UV HPLC spectroscopic, 99.0%, EN300-19337, C05979,
Q14985, A837125, InChI=1/C3H8O/c1-2-3-4/h4H,2-3H2,1H, J-505102, 1-Propanol, for inorganic trace analysis, >=99.8%, F0001-1829, 1-Propanol, puriss. p.a., Reag. Ph. Eur., >=99.5% (GC), 1-Propanol, United States Pharmacopeia (USP) Reference Standard, n-Propanol or propyl alcohol, normal [UN1274], 5VQ, Propan-1-ol Other Names: n-Propyl alcohol, n-Propanol, n-PrOH, Ethylcarbinol, 1-Hydroxypropane, Propionic alcohol, Propionyl alcohol, Propionylol, Propyl alcohol, Propylic alcohol, Propylol, (1-hydroxypropane, 1-propanol, anhydrous, alcohol C3, ethyl carbinol, normal-propanol, normal-propyl alcohol, n-propanol, n-propanol (propyl alcohol, normal), OPTAL, OS MOSOL, osmosol extra, propan-1-ol, propanol, propyl alcohol, propyl alcohol, normal, propylic alcohol, Propyl alcohol, n-Propan-1-ol, n-Propanol, n-Propyl alcohol, Ethylcarbinol, Optal, Osmosol extra, Propanol, Propylic alcohol, 1-Propyl alcohol, n-C3H7OH, 1-Hydroxypropane, Propanol-1, Propan-1-ol, n-Propyl alkohol, Alcool propilico, Alcool propylique, Propanole, Propanolen, Propanoli, Propylowy alkohol, UN 1274, Propylan-propyl alcohol, NSC 30300, Alcohol, propyl, n-C3H7OH, Propanol, 1-Propanol, n-Propanol, Propan-1-ol, Propyl Alcohol, femanumber2928, ethyl carbinol, alcoolpropilico, n-propyl alcohol, n-ppropylalcohol, alcoolpropylique, Natural Propyl Alcohol, epapesticidechemicalcode047502, 1 Propanol, 1-Hydroxypropane, 1-Propanol, 1-Propyl alcohol, Alcohol, propyl, Ethyl carbinol, Ethylcarbinol, Hydroxypropane, N Propanol, N-Propan-1-ol, n-Propyl alcohol, n-Propanol, n-PrOH, Ethyl carbinol, 1-Hydroxypropane, Propionic alcohol, Propionyl alcohol, Propionylol, Propyl alcohol, Propylic alcohol, Propylol, 1-Hydroxypropane, 1-Propyl alcohol, Alcohol, propyl, Alcool propilico, Alcool propylique, Ethylcarbinol, N-PROPYL ALCOHOL, NSC 30300, Optal, Osmosol extra, PROPYL ALCOHOL, Propan-1-ol, Propanol, Propanol-1, Propanole, Propanolen, Propanoli, Propylan-propyl alcohol, Propylic alcohol, Propylowy alkohol, UN 1274, n-C3H7OH, n-Propan-1-ol, n-Propanol, n-Propyl alkohol, 1-propanol, propanol, n-propanol, Propyl alcohol, Propan-1-ol, n-Propyl alcohol, ethylcarbinol, 1-hydroxypropane, 1-Hydroxypropane, 1-propanol, 1-Propanol, ethyl carbinol, Ethylcarbinol, n-propan-1-ol, n-Propanol, N-PROPANOL, n-Propyl alcohol, n-Propylalkohol, Optal, Osmosol extra, propan-1-ol, Propan-1-ol, Propane-1-ol, Propanol, propanol-1, Propyl alcohol, UN 1274,
Propan-1-ol (n-propanol) is colorless clear liquid with ethanol-like odor.
Propan-1-ol (n-propanol) is with water, alcohol, ether, hydrocarbon and other solvents miscible.
The chemical properties of Propan-1-ol (n-propanol) are similar to those of other low molecular weight aliphatic primary alcohols.
Propan-1-ol (n-propanol) is miscible with water, ethanol and ether.
Propan-1-ol (n-propanol), also known as propanol or ethylcarbinol, is a member of the class of compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
Thus, Propan-1-ol (n-propanol) is considered to be a fatty alcohol lipid molecule.
Propan-1-ol (n-propanol) is soluble (in water) and an extremely weak acidic compound (based on its pKa).
Propan-1-ol (n-propanol) can be found in a number of food items such as cashew nut, chinese mustard, greenthread tea, and chayote, which makes propyl alcohol a potential biomarker for the consumption of these food products.
Propan-1-ol (n-propanol) can be found primarily in blood, feces, and saliva, as well as in human fibroblasts tissue.
Propan-1-ol (n-propanol) exists in all eukaryotes, ranging from yeast to humans.
In humans, Propan-1-ol (n-propanol) is involved in the sulfate/sulfite metabolism.
Propan-1-ol (n-propanol) is also involved in sulfite oxidase deficiency, which is a metabolic disorder.
Propan-1-ol (n-propanol) belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH and sometimes represented as PrOH or n-PrOH.
Propan-1-ol (n-propanol) is a colourless liquid and an isomer of 2-propanol.
Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH.
This colorless liquid, Propan-1-ol (n-propanol), is also known as propan-1-ol, 1-propyl alcohol, n-propyl alcohol, n-propanol, or simply propanol.
Propan-1-ol (n-propanol) is an isomer of isopropanol (2-propanol, isopropyl alcohol).
Propan-1-ol (n-propanol) has high octane numbers and it is suitable for engine fuel usage.
However, the production of Propan-1-ol (n-propanol) has been too expensive to make it a common fuel.
The research octane number (RON) of Propan-1-ol (n-propanol) is 118 and anti-knock index (AKI) is 108.
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes.
Propan-1-ol (n-propanol) is a primary alcohol with the formula CH3CH2CH2OH.
Propan-1-ol (n-propanol) is also known as 1-propanol, 1-propyl alcohol, n-propyl alcohol, or simply propanol.
Propan-1-ol (n-propanol) is an isomer of propan-2-ol.
Propan-1-ol (n-propanol) (also propan-1-ol, propanol, n-propyl alcohol) is a primary alcohol with the formula CH3CH2CH2OH and sometimes represented as PrOH or n-PrOH.
Propan-1-ol (n-propanol) is a colourless liquid and an isomer of 2-propanol.
Propan-1-ol (n-propanol) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Propan-1-ol (n-propanol) appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.
Flash point of Propan-1-ol (n-propanol) is 53-77 °F.
Propan-1-ol (n-propanol) vapors are heavier than air and mildly irritate the eyes, nose, and throat.
Propan-1-ol (n-propanol) is the parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.
Propan-1-ol (n-propanol) has a role as a protic solvent and a metabolite.
Propan-1-ol (n-propanol) is a short-chain primary fatty alcohol and a member of propan-1-ols.
Propan-1-ol (n-propanol) is a colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Propan-1-ol (n-propanol) is a natural product found in Aloe africana, Cichorium endivia, and other organisms with data available.
Propan-1-ol (n-propanol) is a metabolite found in or produced by Saccharomyces cerevisiae.
Propan-1-ol (n-propanol) is a primary alcohol in which the OH entity is bonded to a primary carbon atom.
Propan-1-ol (n-propanol) (CH3CH2CH2OH) is one of two isomers of propanol (C3H8O); the other is 2-propanol ((CH3)2CHOH).
Propan-1-ol (n-propanol) is a clear, colourless transparent liquid that has a typical sharp musty odour that is comparable with the smell of rubbing alcohol.
Propan-1-ol (n-propanol)belongs to the class of organic compounds known as primary alcohols.
Primary alcohols are compounds comprising the primary alcohol functional group, with the general structure RCOH (R=alkyl, aryl).
Propan-1-ol (n-propanol) is one of the most common types of alcohol.
Propan-1-ol (n-propanol) has the formula CH3CH2CH2OH.
Propan-1-ol, n-propyl alcohol, 1-propyl alcohol, or n-propanol are all names for this colourless oil.
Alcohols are those organic compounds which are characterised by the presence of one, two or more hydroxyl groups (−OH) that are attached to the carbon atom in an alkyl group or hydrocarbon chain.
Propan-1-ol (n-propanol) is the parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.
Propan-1-ol (n-propanol) has a role as a protic solvent and a metabolite.
Propan-1-ol (n-propanol) is a short-chain primary fatty alcohol and a member of propan-1-ols.
Propan-1-ol (n-propanol) appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.
Propan-1-ol (n-propanol) appears as a clear colorless liquid with a sharp musty odor like rubbing alcohol.
Propan-1-ol (n-propanol) is a low molecular weight alcohol that is currently being investigated as an alternative fuel for direct methanol/oxygen fuel cells.
Propan-1-ol (n-propanol) is a colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Propan-1-ol (n-propanol) is a primary alcohol with a molecular formula of CH3(CH2)2OH.
Propan-1-ol (n-propanol) is a colourless, transparent liquid that has a typical sharp musty odor that is comparable with the smell of rubbing alcohol.
Propan-1-ol (n-propanol) is fully miscible in water and freely miscible with all common solvents such as glycols, ketones, alcohols, aldehydes, ethers and aliphatic hydrocarbons.
Propan-1-ol (n-propanol) has a flash point of around 15° C and improves drying in coating applications.
Propan-1-ol (n-propanol) is a compound in which one hydrogen atom in the propane molecule is replaced by a hydroxyl group.
Since the hydroxyl group can replace hydrogen on both ends of the carbon chain or the intermediate carbon atom, two isomers of N-Propan-1-ol (n-propanol) and isopropanol can be formed.
The chemical properties of Propan-1-ol (n-propanol) and ethanol similar to carbon monoxide and hydrogen synthesis of methanol by-products, at room temperature and atmospheric pressure, are colorless transparent liquid, fragrance.
In industry, Propan-1-ol (n-propanol) is prepared from ethylene, carbon monoxide and hydrogen under high pressure and cobalt catalysis, and it is prepared from propylene in the action of sulfuric acid or from acetone by catalytic hydrogenation reaction.
Propan-1-ol (n-propanol) also known as n-propanol, n-propyl alcohol, propionic alcohol and propylol has the chemical formula CH3CH2CH2OH.
Like other alcohols, Propan-1-ol (n-propanol) has a hydroxy group, —OH, attached to a saturated carbon atom.
Propan-1-ol (n-propanol) can be abbreviated as PrOH or (n-PrOH).
Propan-1-ol (n-propanol) is a colorless liquid at room temperature and pressure.
Like other alcohols, Propan-1-ol (n-propanol) can have hydrogen bonds between its molecules which strengthen its intermolecular interactions and result in much higher values of physical properties like melting and boiling points in comparison to many other organic and inorganic substances with similar molecular weights.
For example, while Propan-1-ol (n-propanol) boils at 97 °C, methoxyethane (CH3OCH2CH3) with the same molecular weight but no hydrogen bonds between its molecules boils at 7.4 °C.
Like other alcohols, Propan-1-ol (n-propanol) has both a hydrophilic (literally water loving) group, which is the hydroxy group (—OH), and a hydrophobic (lipophilic or literally fat loving) group which is the propyl group (—CH2CH2CH3).
In addition to Propan-1-ol (n-propanol), another alcohol, 2-propanol or propan-2-ol, exists with the molecular formula of C3H8O which has its hydroxy group attached to the middle carbon (it has the form CH3CHOHCH3).
These two alcohols, propan-1-ol and propan-2-ol, in a broad sense are constitutional (structural) isomers of each other.
In a more specific way, they are position isomers (positional isomers) of each other.
One should note that by constitutional isomerism we mean isomerism between structures differing in constitution like CH3CH2CH2OH, CH3CHOHCH3 and CH3CH2OCH3 as constitutional isomers of each other; while by position isomerism (regioisomerism) we mean isomerism between structures differing in the position of a functional group or substituent on a same parent structure like CH3CH2CH2OH and CH3CHOHCH3 as positional isomers of each other.
Position isomerism can be considered as a specific form of constitutional isomerism.
Propan-1-ol (n-propanol) has some applications like its use as a solvent in the pharmaceutical industry.
Propan-1-ol (n-propanol) is industrially produced by catalytic hydrogenation of propanal (CH3CH2CH=O + H2 —> CH3CH2CH2OH) where propanal itself is obtained from the hydroformylation or oxo reaction of ethylene, carbon monoxide and hydrogen together (H2C=CH2 + CO + H2 —> CH3CH2CH=O).
Propan-1-ol (n-propanol) can also be produced naturally in small amounts by fermentation processes.
Considering its octane number and anti-knock index, Propan-1-ol (n-propanol) is suitable for engine fuel usage which is hindered by its price.
USES and APPLICATIONS of PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry mainly for resins and cellulose esters.
Propan-1-ol (n-propanol) has high octane numbers and it is suitable for engine fuel usage.
Propan-1-ol (n-propanol) is used as a solvent in the pharmaceutical industry, and for resins and cellulose esters.
Propan-1-ol (n-propanol) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Propan-1-ol (n-propanol) is approved for use as a biocide in the EEA and/or Switzerland, for: human hygiene, disinfection, food and animals feeds.
Propan-1-ol (n-propanol) is used in the following products: lubricants and greases, anti-freeze products, coating products, finger paints, washing & cleaning products, adhesives and sealants, polishes and waxes and perfumes and fragrances.
Other release to the environment of Propan-1-ol (n-propanol) is likely to occur from: outdoor use, indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Other release to the environment of Propan-1-ol (n-propanol) is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).
Propan-1-ol (n-propanol) can be found in products with material based on: wood (e.g. floors, furniture, toys).
Propan-1-ol (n-propanol) is used in the following products: coating products, laboratory chemicals, washing & cleaning products, lubricants and greases, metal working fluids and plant protection products.
Propan-1-ol (n-propanol) is used in the following areas: scientific research and development and health services.
Propan-1-ol (n-propanol) is used for the manufacture of: fabricated metal products, electrical, electronic and optical equipment, machinery and vehicles and textile, leather or fur.
Other release to the environment of Propan-1-ol (n-propanol) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).
Propan-1-ol (n-propanol) is used in the following products: coating products and inks and toners.
Release to the environment of Propan-1-ol (n-propanol) can occur from industrial use: formulation of mixtures, manufacturing of the substance, formulation in materials and in processing aids at industrial sites.
Propan-1-ol (n-propanol) is used in the following products: laboratory chemicals, coating products, pharmaceuticals, washing & cleaning products, lubricants and greases and metal working fluids.
Propan-1-ol (n-propanol) has an industrial use resulting in manufacture of another substance (use of intermediates).
Propan-1-ol (n-propanol) is used in the following areas: health services and formulation of mixtures and/or re-packaging.
Propan-1-ol (n-propanol) is used for the manufacture of: chemicals.
Release to the environment of Propan-1-ol (n-propanol) can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release and manufacturing of the substance.
Release to the environment of Propan-1-ol (n-propanol) can occur from industrial use: manufacturing of the substance, formulation of mixtures and in processing aids at industrial sites.
Density of Propan-1-ol (n-propanol) approximately is 6.5 lb / gal.
Propan-1-ol (n-propanol) is used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry, mainly for resins and cellulose esters, and, sometimes, as a disinfecting agent.
Pharmaceuticals, floor polishes, dental lotions, lacquers, printing inks, natural gums, pigments, intermediates, dye solutions, antifreeze, gasoline additives, paint additives, and degreasing fluids all use Propan-1-ol (n-propanol) as a solvent.
Propan-1-ol (n-propanol) has low acute toxicity for animals when administered via the dermal, inhalation, or oral routes; it is not irritating to the skin, and dermal absorption is expected to be sluggish. n-Propan-1-ol (n-propanol) is easily metabolized and has no carcinogenic or mutagenic properties.
Propan-1-ol (n-propanol) is used as a solvent, in many cases can replace the lower boiling point of ethanol.
Propan-1-ol (n-propanol) is also used as a coupling and dispersing agent in the pharmaceutical and chemicals industries.
Propan-1-ol (n-propanol) is used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.
Propan-1-ol (n-propanol) is used in making cosmetics, skin and hair preparations, pharmaceuticals, perfumes, lacquer formulations, dye solutions, antifreezes, rubbing alcohols, soaps, window cleaners, acetone and other chemicals and products.
Propan-1-ol (n-propanol) is used as a solvent or to make other solvents including antifreezes, lacquer formulas, soaps, dye solutions, and window cleaners.
In the printing industry and in printing ink, Propan-1-ol (n-propanol) compounds such as isopropanol or isopropyl alcohol are most widely used.
In pharmaceutics, hospitals, clean rooms, and electronics or medical device manufacturing, Propan-1-ol (n-propanol) is the most popular and widely used disinfectant.
Tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm problems, and other heart or circulatory issues are treated with Propan-1-ol (n-propanol).
Propan-1-ol (n-propanol)’s also used to treat or avoid heart attacks, as well as to lessen the severity and frequency of migraines.
Propan-1-ol (n-propanol), also known as n-propyl alcohol or 1-propanol, is one of two isomeric alcohols used in chemical processing as solvents and intermediates.
Propan-1-ol (n-propanol) is most commonly used as a solvent in cosmetics and pharmaceuticals, as well as in lacquer preparation.
Propan-1-ol (n-propanol) produces a variety of esters and ethers, some of which are commercially valuable.
Propan-1-ol (n-propanol) is generally used as a solvent.
Propan-1-ol (n-propanol) is a good solvent, can be directly or through the synthesis of propyl acetate for coating, printing ink, daily chemical products and other fields.
N-propylamine, propylacetate, propylurea, 2-methyl-2-pentanol, n-bromopropane, perfluoropropionic acid, propylparaben and propylparaben can be synthesized from Propan-1-ol (n-propanol).
Propan-1-ol (n-propanol) in the pharmaceutical industry for the production of probenecid, sodium valproate, erythromycin, propylamine sulfate, 2, 5-pyridinedicarboxylic acid dipropyl ester.
The most important derivative of Propan-1-ol (n-propanol) is N-propylamine, which is mainly used in the production of pesticides such as azulene, endazole, isopropramine, trifluralin, and caecones.
Propan-1-ol (n-propanol) can also be produced naturally in small amounts by fermentation processes.
Considering its octane number and anti-knock index, Propan-1-ol (n-propanol) is suitable for engine fuel usage which is hindered by its price.
Propan-1-ol (n-propanol) is used solvent, desinfective agent, analytical reagent, substrate for organic syntheses.
Propan-1-ol (n-propanol) is formed naturally in small amounts during many fermentation processes and used as a solvent in the pharmaceutical industry, mainly for resins and cellulose esters, and, sometimes, as a disinfecting agent.
Propan-1-ol (n-propanol) is generally used as a solvent, is also the preparation of N-propylamine and other raw materials.
Propan-1-ol (n-propanol) is used as chromatographic analysis reagents, solvents and cleaning agents.
Propan-1-ol (n-propanol) is used extraction solvents; GB 27601996: food flavors, food processing aids..
Propan-1-ol (n-propanol) is directly used as a solvent or synthesis of propyl acetate, used in Coating solvents, printing inks, cosmetics, etc.
Propan-1-ol (n-propanol) is used in the production of pharmaceuticals, pesticide intermediates N-propylamine, used in the production of feed additives, synthetic spices, etc.
Propan-1-ol (n-propanol) is used in the pharmaceutical industry for the production of probenecid, sodium valproate, erythromycin, Jiantian, adhesive hemostatic agent BCA, propylthiamine, 2, 5-pyridinedicarboxylic acid dipropyl Ester, etc, used in food additives, plasticizers, spices and many other aspects; Propan-1-ol (n-propanol) derivatives, especially di-n-propylamine in medicine, pesticide production has many applications, used to produce pesticide sulfamethoxazole, bacteria killing, isopropylamine, maimao, sulfolin, flumol, etc.
Propan-1-ol (n-propanol) is used as a solvent, in many cases can replace the lower boiling point of ethanol.
Propan-1-ol (n-propanol) is used solvents and cleaning agents for vegetable oils, natural rubber, resins and cellulose esters.
Propan-1-ol (n-propanol) is generally used as a solvent.
Propan-1-ol (n-propanol) can be used in Coating solvents, printing inks, cosmetics, etc., for the production of pharmaceuticals, pesticides, intermediates for the production of N-propylamine, for the production of feed additives, synthetic spices.
Propan-1-ol (n-propanol) in the pharmaceutical industry, food additives, plasticizers, spices and many other areas have a wide range of applications.
-Propan-1-ol (n-propanol) is used as fuel:
Propan-1-ol (n-propanol) has high octane number and is suitable for engine fuel usage.
However, Propan-1-ol (n-propanol) is too expensive to use as a motor fuel.
The research octane number (RON) of Propan-1-ol (n-propanol) is 118, and anti-knock index (AKI) is 108.
-Industry Uses of Propan-1-ol (n-propanol):
Propan-1-ol (n-propanol) is used as a solvent in the manufacturing of pharmaceuticals, polishes, dental lotions, coatings, lacquers, printing inks, natural gums, pigments, intermediates, dye solutions, antifreeze, fuel additives, paint additives and de-greasing fluids.
Propan-1-ol (n-propanol) is also used as a chemical intermediate to create esters, halides, propyl amines and propyl acetate.
The end-user markets of Propan-1-ol (n-propanol) are the cosmetics, cleaning, motor, printing, coatings and chemical industries.
Propan-1-ol (n-propanol) is also used as fuel in engines due to its high-octane count.
However, due to its expensive nature and low energy gains, Propan-1-ol (n-propanol) is not commonly used.
Commercial Uses: Propan-1-ol (n-propanol) is used as a solvent in antifoaming in cosmetics, perfumes, flavours, fragrances, air care products, cleaning and furnishing products, paints, coatings, inks, personal care products, soaps and window cleaner.
STRUCTURE OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is one of the most common types of alcohol.
Propan-1-ol (n-propanol) has the formula CH3CH2CH2OH.
Propan-1-ol, n-propyl alcohol, 1-propyl alcohol, or n-propanol are all names of this colourless oil.
PREPARATION OF PROPAN-1-OL (n-PROPANOL):
*From Propionaldehyde:
Propionaldehyde is catalytically hydrogenated to produce Propan-1-ol (n-propanol).
Propionaldehyde is made by hydroformylation ethylene with carbon monoxide and hydrogen in the presence of a catalyst like cobalt octacarbonyl or a rhodium complex in the oxo phase.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
The synthesis of methanol (methyl alcohol) from carbon monoxide and hydrogen produces propyl alcohol as a by-product.
Propan-1-ol (n-propanol) can also be found in fusel oil.
Propan-1-ol (n-propanol) is most commonly used as a solvent in cosmetics and pharmaceuticals, as well as in lacquer preparation.
Propan-1-ol (n-propanol) is a colourless, flammable, and aromatic liquid that is miscible in all proportions with water and is moderately toxic.
CHEMICAL AND PHYSICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is colorless, transparent liquid with pungent scent, inflammable, soluble in water and ethanol.
CHEMICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) shows the normal reactions of a primary alcohol.
Thus Propan-1-ol (n-propanol) can be converted to alkyl halides; for example red phosphorus and iodine produce 1-iodopropane in 90% yield, while PCl3 with catalytic ZnCl2 gives 1-chloropropane.
Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing Propan-1-ol (n-propanol) overnight with formic acid alone can produce propyl formate in 65% yield.
Oxidation of Propan-1-ol (n-propanol)with Na2Cr2O7 and H2SO4 gives only a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.
Oxidation of Propan-1-ol (n-propanol) with chromic acid yields propionic acid.
Some example reactions of 1-propanol:
Propan-1-ol (n-propanol) shows the normal reactions of a primary alcohol.
Thus Propan-1-ol (n-propanol) can be converted to alkyl halides; for example red phosphorus and iodine produce n-propyl iodide in 80% yield, while PCl3 with catalytic ZnCl2 gives n-propyl chloride.
Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing propanol overnight with formic acid alone can produce propyl formate in 65% yield.
Oxidation of Propan-1-ol (n-propanol) with Na2Cr2O7 and H2SO4 gives a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.
Oxidation with chromic acid yields propionic acid.
PREPARATION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is manufactured by catalytic hydrogenation of propionaldehyde.
Propionaldehyde is produced via the oxo process by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of Propan-1-ol (n-propanol) involves treating n-propyl iodide with moist Ag2O.
ALTERNATIVE PARENTS OF PROPAN-1-OL (n-PROPANOL):
*Hydrocarbon derivatives
SUBSTITUENTS OF PROPAN-1-OL (n-PROPANOL):
*Hydrocarbon derivative
*Primary alcohol
*Aliphatic acyclic compound
PRODUCTION METHODS OF PROPAN-1-OL (n-PROPANOL):
*Recovery method from isopropanol by-products when propylene is directly hydrated to isopropanol, the by-product is N-propanol, from which the n-propanol is recovered.
*Hydrogenation of propylene oxide.
Propionaldehyde hydrogenation method from propionaldehyde, acrolein hydrogenation of N-propanol and allyl alcohol.
*Hydrogenation of allyl alcohol.
*Methanol method.
Oxo-ethene synthesis.
Derived from the oxidation of natural gas by carbon hydride.
Made from fusel oil.
PHYSICAL AND CHEMICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is a colorless transparent liquid.
Propan-1-ol (n-propanol) has an ethanol-like odor.
Propan-1-ol (n-propanol) is a small amount is present in the fusel oil.
Density 0.8036.
Refractive index 1.3862.
Melting Point -127 °c.
Boiling point 97.19 °c.
Propan-1-ol (n-propanol) is soluble in water, ethanol and ether.
The vapor forms of Propan-1-ol (n-propanol) an explosive mixture with air, with an explosion limit of 2.5% to 8.7% by volume.
PREPARATION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is a major constituent of fusel oil, a by-product formed from certain amino acids when potatoes or grains are fermented to produce ethanol.
This is no longer a significant source of the material.
Propan-1-ol (n-propanol) is manufactured by catalytic hydrogenation of propionaldehyde.
The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
(1) H2C=CH2 + CO + H2 → CH3CH2CH=O
(2) CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of Propan-1-ol (n-propanol) involves treating 1-iodopropane with moist Ag2O.
HISTORY OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) was discovered in 1853 by Chancel, who obtained it by fractional distillation of fusel oil.
PREPARATION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is manufactured by catalytic hydrogenation of propionaldehyde.
Propionaldehyde is produced via the oxo process by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
A traditional laboratory preparation of Propan-1-ol (n-propanol) involves treating n-propyl iodide with moist Ag2O.
CHEMICAL PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) shows the normal reactions of a primary alcohol.
Thus Propan-1-ol (n-propanol) can be converted to alkyl halides; for example red phosphorus and iodine produce n-propyl iodide in 80% yield, while PCl3 with catalytic ZnCl2 gives n-propyl chloride.
Reaction with acetic acid in the presence of an H2SO4 catalyst under Fischer esterification conditions gives propyl acetate, while refluxing Propan-1-ol (n-propanol) overnight with formic acid alone can produce propyl formate in 65% yield.
Oxidation of Propan-1-ol (n-propanol) with Na2Cr2O7 and H2SO4 gives a 36% yield of propionaldehyde, and therefore for this type of reaction higher yielding methods using PCC or the Swern oxidation are recommended.
Oxidation with chromic acid yields propionic acid.
PREPARATION METHOD OF PROPAN-1-OL (n-PROPANOL):
propionaldehyde is synthesized from ethylene by carbonyl, and then Propan-1-ol (n-propanol) is obtained by hydrogenation.
Alternatively, Propan-1-ol (n-propanol) can be directly formed from ethylene and water using metal carbonyl compounds as catalysts.
Propan-1-ol (n-propanol) can also be prepared by liquid phase oxidation using propane or butane as a raw material.
CHEMICAL STRUCTURE OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is miscible in water and freely miscible with all common solvents such as glycols, ketones, alcohols, aldehydes, ethers and aliphatic hydrocarbons.
Propan-1-ol (n-propanol) is primarily used as a solvent in the manufacturing of pharmaceuticals, cosmetics, coatings and as a chemical intermediate.
HOW IS PROPAN-1-OL (n-PROPANOL) PRODUCED?
Normal Propan-1-ol (n-propanol) is manufactured by a catalytic hydrogenation of propionaldehyde.
The propionaldehyde is itself produced via the oxo process, by hydroformylation of ethylene using carbon monoxide and hydrogen in the presence of a catalyst such as cobalt octacarbonyl or a rhodium complex.
Hydrogenation is the process of adding pairs of hydrogen atoms to unsaturated compounds, with the aim of saturating these compounds.
H2C=CH2 + CO + H2 → CH3CH2CH=O
CH3CH2CH=O + H2 → CH3CH2CH2OH
HANDLING, STORAGE AND DISTRIBUTION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) has an NFPA health rating of 1.
Propan-1-ol (n-propanol) sits in the alcohol and polyol reactive groups.
Propan-1-ol (n-propanol) reacts with alkali metal, nitrides, oxoacids and carboxylic acids.
Propan-1-ol (n-propanol) is not reactive with strong oxidising agents.
Propan-1-ol (n-propanol) reacts the same way as primary alcohols.
Propan-1-ol (n-propanol) can be converted to alkyl halides (red phosphorus, iodine), acetic acid to give propyl acetate and chromic acids to give propionic acid.
STORAGE AND DISTRIBUTION OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) is typically bulk stored within a petrochemical storage facility for regulation.
Storage is normally in a cool, dry and well ventilated facility away from oxidising agents.
Propan-1-ol (n-propanol) should be kept out of direct sunlight, heat, and open flames.
Propan-1-ol (n-propanol) can be stored in drummed containers such as iso tanks made of stainless steel, aluminium or carbon steel.
DIFFERENCE BETWEEN PROPAN-1-OL (n-PROPANOL) AND ISOPROPYL ALCOHOL:
Propyl alcohol, also known as n-propyl alcohol or Propan-1-ol (n-propanol), is one of two isomeric alcohols used in chemical processing as solvents and intermediates.
Isopropyl alcohol is the second isomer (2-propanol).
Position isomerism can be seen in n-propyl alcohol and isopropyl alcohol.
Constitutional isomers have the same carbon skeleton and functional groups, but the functional groups are in different places.
The OH group is present on the first C atom in n-propyl alcohol.
The OH group is present on the second C atom in isopropyl alcohol.
When heated with I2 and NaOH solution, isopropyl alcohol produces a yellow iodoform precipitate, while n-propyl does not.
PREPARATION OF PROPAN-1-OL (n-PROPANOL):
a clean production process for the hydrogenation of propionaldehyde to produce Propan-1-ol (n-propanol), comprising the following steps: a, when the crude Propan-1-ol (n-propanol) generated by the hydrogenation of propionaldehyde enters the distillation system, the stripping tower condenses and exchanges the three-phase azeotrope residue formed by the reaction by-product propyl propionate, water and Propan-1-ol (n-propanol), the gas phase material separated by the pervaporation membrane dehydration device is condensed to obtain wastewater A, which is mixed with the raw material propionaldehyde and enters the system again, the condensed residual gas is evacuated by a vacuum pump;
The liquid phase material separated by the pervaporation membrane dehydration unit is sent to rectification to separate Propan-1-ol (n-propanol) and propyl propionate in the liquid phase material.
CONTENT ANALYSIS OF PROPAN-1-OL (n-PROPANOL):
the content of Propan-1-ol (n-propanol) and volatile impurities was determined by gas chromatography (GT-10-4) using a polar column.
PURIFICATION METHOD OF PROPAN-1-OL (n-PROPANOL):
a chromatographic pure Propan-1-ol (n-propanol) preparation method, the specific preparation steps are as follows:(1) take 50g shell type activated carbon, after drying at 150 ° C for 8 hours, put it in a desiccator for cooling;(2) take 1000ml of analytical pure Propan-1-ol (n-propanol) into an extraction bottle, add 50g step (1) after the pre-treated activated carbon is shaken for 30 minutes, it is placed for 10 hours, the activated carbon is filtered out, and the Propan-1-ol (n-propanol) is put into a 1000ml three-mouth distillation bottle; (3) after the rectification equipment is installed as required, the step (2) after further rectification of medium-Propan-1-ol (n-propanol), the reflux ratio was adjusted to 2:30, and 96.5-97.5 fractions were collected to obtain chromatographically pure Propan-1-ol (n-propanol), which was sampled and analyzed.
Inspection was conducted according to Q/12HB3730-2010 standard, and the yield of the finished product was about 88%.
REACTIVITY PROFILE OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) reacts with oxoacids and carboxylic acids to form esters plus water.
Propan-1-ol (n-propanol) is converted by oxidizing agents to propanal or propionic acid.
Propan-1-ol (n-propanol) may initiate the polymerization of isocyanates and epoxides.
Propan-1-ol (n-propanol) is incompatible with strong oxidizing agents.
PROPERTIES OF PROPAN-1-OL (n-PROPANOL):
Propan-1-ol (n-propanol) forms binary azeotropes with acetal, benzene, biacetyl,1-bromobutane, 2-bromobutane, n-butyl chloride, butyl formate, carbon tetrachloride, chlorobenzene, 1-chlorobutane, 2-chlorobutane, 1-chloro-3-methylbutane, 1-chloro-2-methylpropane, diethoxymethane, dioxane, di-n-propyl ether, ethyl propionate, ethyl sulfide, ethylene chloride, fluorobenzene, n-hexane, 1-iodobutane, 2-iodobutane, 1-iodo-2-methylpropane, isobutyl formate, isobutyronitrile, methyl acrylate, 3-methyl-2-butanol, methyl butyrate, methyl isobutyrate, 2-pentanone, 3-pentanone, alpha-pinene, propyl acetate, n-propyl bromide, propyl formate, toluene, water.
Propan-1-ol (n-propanol) forms ternary azeotropes with water, acetaldehyde dipropylacetal; water, benzene; water, carbon tetrachloride; water, 1,3-cyclohexadiene; water, cyclohexane; water, cyclohexene; water, dipropoxymethane; water, ethoxypropoxymethane; water, 3-iodopropene; water, nitromethane; water, 3-pentanone; water, propyl acetate; water, propyl chloroacetate; water, propyl ether; water, propyl formate; water, trichloroethylene
PHYSICAL and CHEMICAL PROPERTIES of PROPAN-1-OL (n-PROPANOL):
Chemical formula: C3H8O
Molar mass: 60.096 g·mol−1
Appearance: Colorless liquid
Odor: mild, alcohol-like
Density: 0.803 g/mL
Melting point: −126 °C; −195 °F; 147 K
Boiling point: 97 to 98 °C; 206 to 208 °F; 370 to 371 K
Solubility in water: miscible
log P: 0.329
Vapor pressure: 1.99 kPa (at 20 °C)
Acidity (pKa): 16
Basicity (pKb): −2
Magnetic susceptibility (χ): −45.176·10−6 cm3/mol
Refractive index (nD): 1.387
Viscosity: 1.959 mPa·s (at 25 °C)
Dipole moment: 1.68 D
Heat capacity (C): 143.96 J/(K·mol)
Std molar entropy (S⦵298): 192.8 J/(K·mol)
Std enthalpy of formation (ΔfH⦵298): −302.79…−302.29 kJ/mol
Std enthalpy of combustion (ΔcH⦵298): −2.02156…−2.02106 MJ/mol
Molecular Weight: 60.10 g/mol
XLogP3: 0.3
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 1
Exact Mass: 60.057514874 g/mol
Monoisotopic Mass: 60.057514874 g/mol
Topological Polar Surface Area: 20.2Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 7.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical and physical properties of n-propanol:
Molecular Formula: CH3CH2CH2OH / n-PrOH
Synonyms: 1-propanol, n-propanol alcohol, propan-1-ol,
propyl alcohol, n-PrOH, 1-hydroxypropane, propionic alcohol
Cas Number: 71-23-8
Molecular Mass: 60.096 g/mol-1
Exact Mass: 60.057515 g/mol
Flashpoint: 77 °F / 22 °C
Boiling Point: 207 °F (at 760 mm Hg) / 97.2 °C
Melting Point: -195 °F / -126 °C
Vapour Pressure: 1.99 kPa (at 20 °C)
Water Solubility: miscible
Density: 0.803 g/mL
Log P: 0.329
Physical state: clear, liquid
Color: colorless
Odor: alcohol-like
Melting point/freezing point:
Melting point/range: -127 °C - lit.
Initial boiling point and boiling range: 97 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 13,7 %(V)
Lower explosion limit: 2,1 %(V)
Flash point: 22 °C - closed cup
Autoignition temperature: 400 °C at 1.013,25 hPa
Decomposition temperature: No data available
pH: 8,5 at 200 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 2,21 mPa.s at 20 °C
Water solubility: at 20 °C completely miscible
Partition coefficient: n-octanol/water:
log Pow: 0,2 at 25 °C - Bioaccumulation is not expected.
Vapor pressure: 19,3 hPa at 20 °C
Density: 0,804 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 23,45 mN/m at 20 °C
Relative vapor density: 2,07 - (Air = 1.0)
Boiling point: 96.5 - 98 °C (1013 hPa)
Density: 0.8 g/cm3 (20 °C)
Explosion limit: 2.1 - 19.2 %(V)
Flash point: 22 °C
Ignition temperature: 360 °C
Melting Point: -127 °C
pH value: 8.5 (200 g/l, H₂O, 20 °C)
Vapor pressure: 19.3 hPa (20 °C)
pH: 7
Melting Point: -127°C
Color: Colorless
Formula Weight:60.1g/mol
Boiling Point: 97°C
Physical Form: Liquid
Vapor Pressure: 25mbar at 20°C
Viscosity: 2.2 mPaS at 20°C
CAS: 71-23-8
EINECS: 200-746-9
InChI: InChI=1/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
Molecular Formula: C3H8O
Molar Mass: 60.1
Density: 0.804 g/mL at 25 °C(lit.)
Melting Point: -127°C(lit.)
Boling Point: 97°C(lit.)
Flash Point: 59°F
JECFA Number: 82
Water Solubility: soluble
Solubility: H2O: passes test
Vapor Presure: 10 mm Hg ( 147 °C)
Vapor Density: 2.1 (vs air)
Appearance: Liquid
Color: <10(APHA)
Odor: Resembles that of ethyl alcohol.
Maximum wavelength(λmax):
['λ: 220 nm Amax: ≤0.40', , 'λ: 240 nm Amax: ≤0.071', 'λ: 275 nm Amax: ≤0.0044']
Merck: 14,7842
BRN: 1098242
pKa: >14 (Schwarzenbach et al., 1993)
PH: 7 (200g/l, H2O, 20℃)
Storage Condition: Store at +5°C to +30°C.
Stability: Stable.
Molecular Weight：60.095
Exact Mass：60.0575
EC Number：200-746-9
UNII：96F264O9SV
ICSC Number：0553
NSC Number：30300
UN Number：1274
DSSTox ID：DTXSID2021739
Color/Form：Colorless liquid.
HScode：2905121000
PSA：20.23
XLogP3：0.3887
Appearance：colourless liquid
Density：0.8
Melting Point：-127ºC
Boiling Point：97ºC
Flash Point：15ºC
Refractive Index：1.384-1.386
Water Solubility：soluble
Storage Conditions：Store at RT.
Vapor Pressure：10 mm Hg ( 147 °C)
Vapor Density：2.1 (vs air)
Odor：Similar to ethanol
Odor perception threshold: <0.07-100 mg/cu-m;
odor recognition threshold: 0.32-150 mg/cu m
Taste： CHARACTERISTIC RIPE, FRUITY FLAVOR
OH：5.53e-12 cm3/molecule*sec
Henrys Law Constant：7.41e-06 atm-m3/mole
Henry's Law constant = 7.41X10-6 atm-cu m/mol @ 25 °C
Dissociation Constants：
pKa = 16.10
Heat of fusion: 20.66 cal/g
Heat of solution: (est) -9 BTU/lb= -5 cal/g= -0.2X10+5 J/kg
Reid Vapor Pressure: 0.87 psia
Liquid heat capacity= 0.566 BTU/lb-F @ 70 °F
Ideal gas heat capacity= 0.345 BTU/lb-F @ 75 °C
Water Solubility: 391 g/L
logP: 0.21
logP: 0.36
logS: 0.81
pKa (Strongest Acidic): 16.85
pKa (Strongest Basic): -2
Physiological Charge: 0
Hydrogen Acceptor Count: 1
Hydrogen Donor Count: 1
Polar Surface Area: 20.23 Ų
Rotatable Bond Count: 1
Refractivity: 17.53 m³·mol⁻¹
Polarizability: 7.23 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No
Chemical Formula: C3H8O
IUPAC name: propan-1-ol
InChI Identifier: InChI=1S/C3H8O/c1-2-3-4/h4H,2-3H2,1H3
InChI Key: BDERNNFJNOPAEC-UHFFFAOYSA-N
Isomeric SMILES: CCCO
Average Molecular Weight: 60.095
Monoisotopic Molecular Weight: 60.057514878
FIRST AID MEASURES of PROPAN-1-OL (n-PROPANOL):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available
ACCIDENTAL RELEASE MEASURES of PROPAN-1-OL (n-PROPANOL):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.
FIRE FIGHTING MEASURES of PROPAN-1-OL (n-PROPANOL):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.
EXPOSURE CONTROLS/PERSONAL PROTECTION of PROPAN-1-OL (n-PROPANOL):
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 120 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181)
-Control of environmental exposure:
Do not let product enter drains.
HANDLING and STORAGE of PROPAN-1-OL (n-PROPANOL):
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
Storage conditions
Keep container tightly closed in a dry and well-ventilated place.
Keep away from heat and sources of ignition.
STABILITY and REACTIVITY of PROPAN-1-OL (n-PROPANOL):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
