Textile, Leather, Paper and Industrial Chemicals

POLYETHYLENE GLYCOL
SYNONYMS PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); CAS NO. 25322-68-3
Polyethylene Glycol (PEG)
PEG; Polyglycol; Polyethylene oxide; Polyoxy ethylene; Polyethylene Glycol 200; Polyethylene Glycol 400; Polyethylene Glycol 300; Polyethylene Glycol 600; Polyethylene Glycol 1500; Polyethylene Glycol 4000; Polyethylene Glycol 8000; Polyethylene Glycol 6000; CAS NO: 25322-68-3
POLYETHYLENE GLYCOL (PEG) 200

Polyethylene glycol (PEG) 200 is a polyether compound with the chemical formula H(OCH2CH2)nOH, where "n" represents the average number of ethylene glycol units.
In the case of Polyethylene glycol (PEG) 200, "n" is approximately 4.

CAS Number: 25322-68-3
EC Number: 500-038-2

Polyethylene glycol 200, PEG 200, Polyethylene oxide monobutyl ether 200, PEG ether 200, Polyethylene oxide monoethyl ether 200, PEG-4 methyl ether, Polyethylene oxide 200 monomethyl ether, PEG 200 monobutyl ether, Macrogol 200 methyl ether, Polyethylene oxide 200 butyl ether, Carbowax 200 monomethyl ether, PEG 200 butyl ether, Polyglycol 200 methyl ether, PEG-4 butyl ether, Polyethylene glycol monobutyl ether 200, Polyethylene glycol 200, PEG 200, Polyethylene oxide monobutyl ether 200, PEG ether 200, Polyethylene oxide monoethyl ether 200, PEG-4 methyl ether, Polyethylene oxide 200 monomethyl ether, PEG 200 monobutyl ether, Macrogol 200 methyl ether, Polyethylene oxide 200 butyl ether, Carbowax 200 monomethyl ether, PEG 200 butyl ether, Polyglycol 200 methyl ether, PEG-4 butyl ether, Polyethylene glycol monobutyl ether 200, Polyethylene glycol butyl ether 200, PEG ether butyl 200, Polyethylene oxide monooctyl ether 200, PEG 200 monooctyl ether, Polyethylene glycol monooctyl ether 200, PEG-4 octyl ether, Polyglycol 200 octyl ether, PEG ether octyl 200, Polyethylene oxide 200 octoxy ether, PEG 200 octoxyethanol, Polyethylene glycol octoxy ether 200, PEG ether octyl 200, Polyethylene oxide monoisoctyl ether 200, PEG 200 monoisoctyl ether, Polyethylene glycol monoisoctyl ether 200, PEG ether isoctyl 200, Polyglycol isoctyl ether 200, PEG-4 isoctyl ether, Polyethylene oxide 200 isoctoxy ether, PEG 200 isoctoxyethanol



APPLICATIONS


Polyethylene glycol (PEG) 200 is extensively used in the pharmaceutical industry as a solubilizing agent for poorly water-soluble drugs.
In cosmetics, Polyethylene glycol (PEG) 200 serves as an emollient and thickening agent in lotions, creams, and personal care products.
Polyethylene glycol (PEG) 200 finds application in the formulation of liquid soaps and shampoos, contributing to their texture and stability.

Polyethylene glycol (PEG) 200 acts as a plasticizer in the production of adhesives and sealants, improving flexibility.
As a lubricant, Polyethylene glycol (PEG) 200 is employed in the textile industry to enhance the processing of fibers.

Polyethylene glycol (PEG) 200 is utilized in the creation of stable emulsions, making it valuable in the food and beverage industry.
In antifreeze solutions, Polyethylene glycol (PEG) 200 helps lower the freezing point, preventing damage to systems in cold temperatures.
Polyethylene glycol (PEG) 200 plays a role in the synthesis of various chemicals, acting as a reactant in diverse reactions.

Polyethylene glycol (PEG) 200 is a common ingredient in skin creams and lotions, providing a smooth and moisturizing feel.
Polyethylene glycol (PEG) 200 is used as a carrier in the food industry for certain food additives, ensuring their even distribution.

Polyethylene glycol (PEG) 200 is employed as a plasticizer in the production of printing inks, enhancing their flow properties.
In the manufacturing of paints and coatings, Polyethylene glycol (PEG) 200 contributes to the formation of stable formulations.
Polyethylene glycol (PEG) 200 serves as a humectant in certain products, helping retain moisture and preventing drying.
Polyethylene glycol (PEG) 200 finds application in the creation of stable suspensions in the agricultural industry.

In the production of rubber and elastomers, Polyethylene glycol (PEG) 200 acts as a processing aid, improving workability.
Polyethylene glycol (PEG) 200 is used in the synthesis of nanoparticles, aiding in their dispersion in various solutions.

Polyethylene glycol (PEG) 200 is employed in the formulation of veterinary pharmaceuticals for enhanced drug delivery.
In the creation of de-icing solutions, Polyethylene glycol (PEG) 200 contributes to preventing ice buildup on surfaces.
Polyethylene glycol (PEG) 200 is used in the formulation of certain industrial cleaning agents for improved efficacy.

Polyethylene glycol (PEG) 200 is a component in the production of brake fluids, ensuring proper functionality in vehicles.
In the field of biotechnology, Polyethylene glycol (PEG) 200 is used in protein crystallization and DNA precipitation.
Polyethylene glycol (PEG) 200 is employed in the development of stable ink formulations for inkjet printers.

Polyethylene glycol (PEG) 200 is utilized in the creation of certain herbicides for improved dispersion and effectiveness.
Polyethylene glycol (PEG) 200 finds application in the creation of stable suspensions for diagnostic imaging agents.
In the oil and gas industry, Polyethylene glycol (PEG) 200 is used in drilling fluids to control rheological properties.

Polyethylene glycol (PEG) 200 is employed in the formulation of stable inkjet printer inks, contributing to consistent printing performance.
Polyethylene glycol (PEG) 200 serves as a key ingredient in the creation of coolant formulations for efficient heat transfer in automotive systems.

In the field of biopharmaceuticals, Polyethylene glycol (PEG) 200 is used in protein purification processes to prevent protein aggregation.
Polyethylene glycol (PEG) 200 finds application in the production of thermosetting resins, enhancing their flexibility and workability.

Polyethylene glycol (PEG) 200 is utilized in the creation of lubricating agents for metalworking processes, reducing friction.
Polyethylene glycol (PEG) 200 acts as a dispersant in the formulation of ceramic glazes, ensuring even coating on surfaces.
In the textile industry, PEG 200 is applied as a dyeing assistant, improving the evenness of dye distribution.

Polyethylene glycol (PEG) 200 is used in the production of certain antifoaming agents to control foam formation in industrial processes.
Polyethylene glycol (PEG) 200 is a common component in the manufacturing of bubble bath formulations for enhanced foaming.
In the agricultural sector, Polyethylene glycol (PEG) 200 is utilized in the formulation of pesticides for improved solubility and efficacy.

Polyethylene glycol (PEG) 200 is employed in the creation of stable suspensions for magnetic resonance imaging (MRI) contrast agents.
Polyethylene glycol (PEG) 200 plays a role in the production of lithium-ion battery electrolytes, ensuring ion conductivity.

Polyethylene glycol (PEG) 200 is used in the preparation of stable emulsions for the pharmaceutical industry, aiding drug delivery.
Polyethylene glycol (PEG) 200 acts as a dispersing agent in the formulation of ceramic slurries for the production of advanced ceramics.

In the creation of metalworking fluids, PEG 200 serves as a lubricating and cooling additive.
Polyethylene glycol (PEG) 200 finds application in the formulation of water-based drilling fluids in the oil and gas industry.

Polyethylene glycol (PEG) 200 is utilized in the creation of certain brake fluids to ensure proper lubrication and functionality in braking systems.
Polyethylene glycol (PEG) 200 is applied in the production of adhesive formulations for improved bond strength and flexibility.

Polyethylene glycol (PEG) 200 is used in the preparation of certain dental products, including impression materials.
Polyethylene glycol (PEG) 200 is employed in the creation of stable suspensions for magnetic particle imaging (MPI) contrast agents.

Polyethylene glycol (PEG) 200 serves as a humectant in the formulation of certain tobacco products to prevent drying.
In the paper and pulp industry, PEG 200 is used as a wetting agent to improve paper quality.

Polyethylene glycol (PEG) 200 is applied in the creation of stable suspensions for the delivery of therapeutic nanoparticles.
Polyethylene glycol (PEG) 200 is used in the formulation of certain liquid detergents for improved solubility and cleaning efficiency.
Polyethylene glycol (PEG) 200 plays a role in the production of certain biodegradable polymers, contributing to their processing properties.

Polyethylene glycol (PEG) 200 is utilized in the formulation of stable suspensions for the controlled release of agrochemicals in precision agriculture.
In the creation of certain pharmaceutical ointments, PEG 200 is employed as a base for enhanced topical drug delivery.

Polyethylene glycol (PEG) 200 plays a role in the synthesis of nanoparticles for drug delivery systems, ensuring controlled release and improved bioavailability.
Polyethylene glycol (PEG) 200 is used in the preparation of cryoprotective solutions for the preservation of biological samples at low temperatures.

In the field of tissue engineering, Polyethylene glycol (PEG) 200 is applied in the creation of hydrogels for cell encapsulation and growth.
Polyethylene glycol (PEG) 200 is employed in the formulation of certain veterinary medicines for enhanced solubility and palatability.
Polyethylene glycol (PEG) 200 acts as a plasticizer in the production of moldable plastic compounds, contributing to their flexibility.
Polyethylene glycol (PEG) 200 is used in the creation of stable suspensions for the delivery of contrast agents in medical imaging.

In the formulation of certain herbicides, Polyethylene glycol (PEG) 200 aids in the dispersion of active ingredients for optimal efficacy.
Polyethylene glycol (PEG) 200 is applied in the creation of stable emulsions for the formulation of photodynamic therapy agents in medicine.
Polyethylene glycol (PEG) 200 serves as a wetting agent in the formulation of herbicidal sprays for improved coverage on plant surfaces.

Polyethylene glycol (PEG) 200 is utilized in the creation of stable suspensions for the delivery of therapeutic RNA molecules.
In the field of regenerative medicine, Polyethylene glycol (PEG) 200 is used in the development of scaffolds for tissue engineering applications.
Polyethylene glycol (PEG) 200 acts as a lubricant in the production of polymeric materials for 3D printing, improving printability.
Polyethylene glycol (PEG) 200 is employed in the creation of stable suspensions for the delivery of contrast agents in diagnostic radiology.

In the formulation of certain antifungal agents, Polyethylene glycol (PEG) 200 aids in improving solubility and bioavailability.
Polyethylene glycol (PEG) 200 is used in the production of certain ink formulations for printing on various substrates.
Polyethylene glycol (PEG) 200 serves as a carrier for the encapsulation of enzymes in biocatalysis applications.

Polyethylene glycol (PEG) 200 plays a role in the creation of stable suspensions for the delivery of therapeutic proteins in biopharmaceuticals.
Polyethylene glycol (PEG) 200 is utilized in the formulation of certain oral care products for enhanced stability and texture.
In the creation of certain wound dressings, Polyethylene glycol (PEG) 200 is applied to enhance moisture retention and promote healing.
Polyethylene glycol (PEG) 200 acts as a dispersant in the formulation of ceramic pastes for the production of advanced ceramics.

Polyethylene glycol (PEG) 200 is employed in the development of stable emulsions for the encapsulation of essential oils in cosmetics.
In the formulation of certain lubricating greases, Polyethylene glycol (PEG) 200 contributes to improved flow properties and stability.
Polyethylene glycol (PEG) 200 is used in the creation of stable suspensions for the delivery of therapeutic antibodies in biomedicine.

Polyethylene glycol (PEG) 200 is employed in the formulation of certain cosmetic and skincare products, acting as a humectant to retain skin moisture.
In the creation of certain mouthwashes and oral care products, Polyethylene glycol (PEG) 200 contributes to the solubility of active ingredients.
Polyethylene glycol (PEG) 200 serves as a stabilizing agent in the formulation of certain vaccines, ensuring the preservation of antigenic properties.

Polyethylene glycol (PEG) 200 is utilized in the preparation of stable emulsions for the delivery of vitamins and nutrients in dietary supplements.
In the field of nanotechnology, Polyethylene glycol (PEG) 200 is applied in the synthesis of stable nanoparticles for drug delivery applications.

Polyethylene glycol (PEG) 200 is used in the formulation of certain hair care products, contributing to improved texture and manageability.
Polyethylene glycol (PEG) 200 acts as a carrier in the creation of certain ink formulations for the printing of flexible electronic devices.
In the formulation of certain dye solutions, Polyethylene glycol (PEG) 200 aids in the dispersion of dyes for even coloring of fabrics.

Polyethylene glycol (PEG) 200 serves as a plasticizer in the production of certain biodegradable polymers for sustainable packaging materials.
Polyethylene glycol (PEG) 200 is employed in the formulation of certain sunscreen products, contributing to their spreadability and stability.

In the development of certain diagnostic assays, Polyethylene glycol (PEG) 200 is applied in the creation of stable assay components.
Polyethylene glycol (PEG) 200 is used in the formulation of certain veterinary vaccines, ensuring the stability of antigens during storage.
Polyethylene glycol (PEG) 200 acts as a dispersant in the creation of stable suspensions for the delivery of contrast agents in medical imaging.
In the field of analytical chemistry, Polyethylene glycol (PEG) 200 is applied in the extraction and purification of certain analytes.

Polyethylene glycol (PEG) 200 is used in the formulation of certain lubricating oils, contributing to improved viscosity and stability.
Polyethylene glycol (PEG) 200 serves as a cryoprotectant in the preservation of certain cell lines and tissues for research purposes.

Polyethylene glycol (PEG) 200 is employed in the creation of stable emulsions for the encapsulation of essential oils in aromatherapy products.
In the field of tissue preservation, Polyethylene glycol (PEG) 200 is applied in the creation of stable solutions for organ storage.
Polyethylene glycol (PEG) 200 acts as a carrier in the formulation of certain pesticide solutions for crop protection.

Polyethylene glycol (PEG) 200 is used in the preparation of stable emulsions for the encapsulation of fragrances in perfumes and colognes.
In the development of certain chromatography columns, Polyethylene glycol (PEG) 200 is applied as a stationary phase for separation.
Polyethylene glycol (PEG) 200 is used in the formulation of certain inkjet printer inks for improved color dispersion.

Polyethylene glycol (PEG) 200 serves as a stabilizer in the creation of certain enzyme formulations for industrial processes.
In the production of certain hydrogels for medical applications, Polyethylene glycol (PEG) 200 contributes to their structural integrity.
Polyethylene glycol (PEG) 200 is employed in the formulation of certain magnetic resonance imaging (MRI) contrast agents for medical diagnostics.



DESCRIPTION


Polyethylene glycol (PEG) 200 is a polyether compound with the chemical formula H(OCH2CH2)nOH, where "n" represents the average number of ethylene glycol units.
In the case of Polyethylene glycol (PEG) 200, "n" is approximately 4.
Polyethylene glycol (PEG) 200 belongs to a class of polymers where the repeating unit is made up of ethylene glycol monomers.

Polyethylene glycol 200, often abbreviated as PEG 200, is a clear and colorless liquid.
Polyethylene glycol (PEG) 200 belongs to the polyethylene glycol family, characterized by its ethylene glycol repeating units.
Polyethylene glycol (PEG) 200 has a relatively low molecular weight, around 200 g/mol, contributing to its liquid state at room temperature.

Polyethylene glycol (PEG) 200 is a versatile and water-soluble polymer widely used in various industrial and pharmaceutical applications.
The clear nature of Polyethylene glycol (PEG) 200 makes it suitable for formulations where color or turbidity is undesirable.
With a high degree of miscibility, Polyethylene glycol (PEG) 200 readily dissolves in water, facilitating its use in aqueous solutions.

Its chemical structure includes repeating units of ethylene oxide, endowing it with surfactant and lubricating properties.
Polyethylene glycol (PEG) 200 is employed in the pharmaceutical industry as an excipient and solubilizing agent in drug formulations.
In cosmetics and personal care products, Polyethylene glycol (PEG) 200 functions as a viscosity modifier and emollient in creams and lotions.

Polyethylene glycol (PEG) 200 is known for its hygroscopic nature, capable of attracting and holding water molecules.
Polyethylene glycol (PEG) 200 is utilized in the industrial sector as a plasticizer and lubricant, enhancing the flow and flexibility of materials.
Its low volatility makes Polyethylene glycol (PEG) 200 suitable for applications where the retention of moisture is important.

In the textile industry, Polyethylene glycol (PEG) 200 is used for fiber lubrication, improving the processing of textiles.
Due to its solubilizing properties, Polyethylene glycol (PEG) 200 aids in the dispersion of various substances in liquid formulations.
Polyethylene glycol (PEG) 200 finds application in the production of antifreeze solutions, contributing to the lowering of freezing points.

Polyethylene glycol (PEG) 200 serves as a stable reactant in chemical syntheses, participating in the formation of diverse compounds.
Polyethylene glycol (PEG) 200 is often incorporated into formulations for liquid soaps, shampoos, and body washes in the personal care sector.
Its role as a plasticizer extends to the formulation of adhesives and sealants, enhancing their flexibility.

Polyethylene glycol (PEG) 200 exhibits low toxicity, contributing to its widespread use in consumer and industrial products.
Polyethylene glycol (PEG) 200's compatibility with various materials makes it suitable for a range of applications in different industries.

Polyethylene glycol (PEG) 200's mild and non-irritating nature makes it suitable for use in gentle and hypoallergenic formulations.
In the food industry, Polyethylene glycol (PEG) 200 may find use as a carrier for certain food additives, aiding in their dispersion.

Its stability under varying storage conditions contributes to its reliability in different manufacturing processes.
Polyethylene glycol (PEG) 200 plays a crucial role in the creation of stable and homogeneous emulsions in the cosmetic and pharmaceutical industries.
As a widely employed polyethylene glycol variant, Polyethylene glycol (PEG) 200 continues to be a valuable component in numerous formulations across diverse sectors.



PROPERTIES


Chemical Properties:

Chemical Formula: H(OCH2CH2)nOH (n is approximately 4 for PEG 200).
Molecular Weight: Approximately 200 g/mol.
Structure: Linear polyether with repeating ethylene glycol units.


Physical Properties:

State: Liquid at room temperature.
Color: Clear and colorless.
Odor: Odorless.
Solubility: Highly soluble in water.
Miscibility: Miscible with various organic solvents.
Hygroscopicity: Attracts and holds water molecules.
Density: 1.142 g/mL.
Melting Point: 4 °C.
Boiling Point: 315 °C.
Viscosity: Low viscosity liquid.
Flash Point: Non-flammable.


Thermochemical Properties:

Heat of Formation: Ranges from -312.1 to -312.1 kJ mol−1.
Heat of Combustion: Ranges from -2.0089 to -2.0145 MJ mol−1.



FIRST AID


Inhalation:

Remove to Fresh Air:
If inhaled, move the affected person to an area with fresh air.

Seek Medical Attention:
If breathing difficulties persist or if the person is unconscious, seek immediate medical attention.


Skin Contact:

Remove Contaminated Clothing:
Take off contaminated clothing, shoes, and accessories.

Flush with Water:
Wash the affected skin area thoroughly with soap and water.

Seek Medical Advice:
If irritation, redness, or other adverse reactions occur, seek medical advice.


Eye Contact:

Flush Eyes:
Immediately flush the eyes with plenty of water for at least 15 minutes, lifting the upper and lower eyelids.

Remove Contact Lenses:
If applicable, remove contact lenses during the flushing process.

Seek Medical Attention:
If irritation or other symptoms persist, seek medical attention promptly.


Ingestion:

Do Not Induce Vomiting:
Do not induce vomiting unless directed to do so by medical personnel.

Rinse Mouth:
If conscious, rinse the mouth with water.

Seek Medical Attention:
Seek immediate medical attention.
Provide medical personnel with information about the ingested substance.


General First Aid Measures:

Personal Protection:
Wear appropriate personal protective equipment (PPE) if providing first aid.

Provide Comfort:
Keep the affected person calm and reassure them.

Monitoring:
Monitor vital signs such as breathing and pulse.

Do Not Leave Unattended:
Do not leave a person who has ingested or come into contact with PEG 200 unattended.

Note to Healthcare Professionals:
Provide medical personnel with detailed information about the substance, including its name, chemical formula, and any known exposure.


Notes:

Medical Attention:
Always seek medical attention if there is uncertainty or if symptoms persist.

Individual Sensitivity:
Individuals may vary in their sensitivity to chemical substances; therefore, responses to exposure can differ.

Product Specifics:
Consult the product's safety data sheet (SDS) for specific first aid measures recommended by the manufacturer.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including safety glasses or goggles, gloves, and protective clothing, to minimize skin and eye contact.

Ventilation:
Use in a well-ventilated area to minimize inhalation exposure.
Ensure adequate general and local exhaust ventilation.

Avoidance of Contact:
Avoid skin contact and inhalation of vapors or mists.
Use mechanical ventilation if necessary.

Preventive Measures:
Implement good industrial hygiene practices. Wash hands and any exposed skin thoroughly after handling.

Storage Compatibility:
Store away from incompatible materials such as strong acids, bases, and oxidizing agents.

Static Electricity:
Ground containers during transfer to prevent the build-up of static electricity.

Handling Precautions:
Follow established handling procedures and protocols.
Do not eat, drink, or smoke while handling the substance.

Spill and Leak Response:
In the case of spills, use appropriate absorbent materials to contain and clean up the substance.
Avoid discharging into drains or water sources.

Equipment Handling:
Use suitable equipment for handling, such as pumps or valves, to minimize the risk of spills.


Storage:

Storage Temperature:
Store Polyethylene glycol (PEG) 200 at room temperature unless otherwise specified by the manufacturer.

Storage Area:
Store in a cool, dry, and well-ventilated area. Keep away from direct sunlight and heat sources.

Segregation:
Segregate from incompatible materials following established storage guidelines.

Containers:
Use appropriate containers made of materials compatible with PEG 200 to prevent contamination or degradation.

Avoidance of Contaminants:
Prevent contamination by keeping containers tightly closed when not in use.

Labeling:
Ensure proper labeling of containers with the substance name, hazards, and handling instructions.

Fire Prevention:
Keep away from open flames and potential ignition sources.
PEG 200 is non-flammable but should be stored away from sources of heat.

Shelf Life:
Follow the manufacturer's recommendations regarding the shelf life of the product.
Check for any signs of degradation before use.

Separation from Food and Feed:
Avoid storing near food, feed, or medications to prevent the risk of contamination.

Controlled Substance:
Store PEG 200 in controlled areas with restricted access, particularly in laboratory or industrial settings.

Emergency Planning:
Be familiar with emergency procedures, including spill response and fire control measures.

Training:
Ensure that personnel handling and storing PEG 200 are adequately trained in safety procedures and emergency response.
POLYETHYLENE GLYCOL 1000
Polyethylene glycol 1000 is used as an excipent in pharmaceutical products.
Polyethylene glycol 1000 is used in the precipitation of proteins as well as in the separation and purification of biomolecules and in the induction of cell hybridization.
Polyethylene glycol 1000 acts as a fusing agent to enhance the effect of macrophages on hybridoma; as a vascular agent in preclinical work; as an anti-foaming agent in food and as the gate insulator in an electric double-layer transistor to enhance superconductivity in an insulator.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

Polyethylene glycol 1000 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: Polyethylene glycol 1000(25322-68-3)
EPA Substance Registry System: Polyethylene glycol 1000 (25322-68-3)

The USP32–NF27 describes Polyethylene glycol 1000 as being an addition polymer of ethylene oxide and water.
Polyethylene glycol grades 200–600 are liquids; grades 1000 and above are solids at ambient temperatures.
Liquid grades Polyethylene glycol 1000 occur as clear, colorless or slightly yellow-colored, viscous liquids.
They have a slight but characteristic odor and a bitter, slightly burning taste.
PEG 600 can occur as a solid at ambient temperatures.
Solid grades (PEG>1000) are white or off-white in color, and range in consistency from pastes to waxy flakes.
They have a faint, sweet odor.
Grades of Polyethylene glycol 1000 and above are available as freeflowing milled powders.

Uses
Polyethylene glycol 1000 molecules of approximately 2000 monomers.
Polyethylene glycol 1000 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown Polyethylene glycol 1000 maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.
In rats, Polyethylene glycol 1000 has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery.
Polyethylene glycol 1000 is industrially produced as a lubricating substance for various surfaces to reduce friction.
POLYETHYLENE GLYCOL 10000
DESCRIPTION:

POLYETHYLENE GLYCOL 10000 is a compound used to modify therapeutic proteins and peptides to increase their solubility
POLYETHYLENE GLYCOL 10000 (PEG 10000), with the CAS number 25322-68-3, is a high molecular weight polymer of ethylene oxide commonly used in various scientific and industrial applications due to its unique physicochemical properties.
POLYETHYLENE GLYCOL 10000, characterized by its long chains and high solubility in water, serves primarily as an inert and non-toxic agent in processes requiring molecular crowding or the alteration of solute mobility and stability.



CAS No.: 25322-68-3
EC Number: 500-038-2
Molecular formula:(C2H4O)nH2O


SYNONYM(S) OF POLYETHYLENE GLYCOL 10000:
Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 10000, PEG


In research, POLYETHYLENE GLYCOL 10000 has been extensively utilized in the field of protein chemistry, where it acts as a precipitant in the crystallization of proteins.
This utility arises from POLYETHYLENE GLYCOL 10000′s ability to exclude volume and reduce water activity around macromolecules, thus promoting the necessary interactions for crystal formation without altering the biological activity of the proteins.

Additionally, POLYETHYLENE GLYCOL 10000 is employed in molecular biology for the preparation of density gradients used in the purification of viruses, nucleic acids, and other macromolecules.
Its role in these applications is pivotal due to its capacity to create a stable environment that supports the separation of biological components based on size and density.
Furthermore, in bioconjugation, POLYETHYLENE GLYCOL 10000 is used to enhance the solubility and stability of bioactive compounds, thereby facilitating a variety of research methodologies that require modified biomolecules for advanced studies.







APPLICATIONS OF POLYETHYLENE GLYCOL 10000:
POLYETHYLENE GLYCOL 10000 is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations.
Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more.
Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.



PHYSICOCHEMICAL INFORMATION ABOUT POLYETHYLENE GLYCOL 10000:
Boiling point >200 °C (1013 hPa) Non applicable
Density 1.2 g/cm3 (20 °C)
Flash point 138.6 °C
Ignition temperature 420 °C
Fusion point 58 - 63 °C
pH value 5 - 7 (100 g/l, H₂O, 20 °C)
Vapor pressure Solubility 550 g/l
Color according to Munsell color system not more intensely colored than reference standard NE12
Melting range (lower value) ≥ 59 °C
Melting range (upper value) ≤ 64 °C
Hydroxyl value 15 - 22
Average molecular mass 5000 - 7500
Identity (IR) passes test
CASE
25322-68-3
Molecular formula
(C2H4O)n
Molecular weight (g/mol)
62.07
MDL number
MFCD01779601
InChI Key
LYCAIKOWRPUZTN-UHFFFAOYSA-NShow more
Synonymous
PEG
IUPAC Name
ethane-1,2-diol
SMILES
[H]OCCO
Chemical name or material Poly(ethylene glycol)
Color White
Fitness Powder or glitter
Fusion point 55.0°C to 60.0°C
Linear formula H ( OCH2CH2 ) nOH
Merck Index 15, 7688
Solubility information Solubility in water: 550g/L (20°C). Other solubilities: soluble in thf
Quantity 1 kg
Formula weight 6000
Hydroxyl value 17 to 20mg KOH/g
Conditioning Plastic bottle
Viscosity 220-262 mPa.s (20°C)
Agency
Ph. Eur.
Quality Level
500
vapor pressure
product line
EMPROVE® ESSENTIAL
form
solid
autoignition temp.
420 °C
mol wt
average Mn 6000
technique(s)
API processing | nano-milling: suitable
pH
5-7 (20 °C, 100 g/L in H2O)
mp
58-63 °C
transition temp
flash point 270 °C
solubility
550 g/L
density
1.2 g/cm3 at 20 °C
application(s)
liquid formulation
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement
storage temp.
15-25°C
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
Distributor reference
528877-100GM
Storage area
France and Germany
DGOS nomenclature
LC13AOOO
Type of coloring
White
Certification
RUO
Sterile device
No
CAS number
25322-68-3
CE DIV marking
No
State
Solid
Barcode
Yes
Subjected to dry ice
No
INSERM nomenclature
NA.NA28
Expiry date on delivery date
12 months
Manufacturer reference
528877-100GM
Nomenclature of Mother-of-pearl
NA.28
Brand
MILLIPORE
Specificity
Solubility: water: 200 mg/mL
Subject to regulation
No
Supplier
SIGMA ALDRICH CHEMISTRY
Quantity
N / A
CEA nomenclature
SGP01
Customs Code
34042000
Manufacturer product label
PEG 10000, MOLECULAR BIOLOGY 1PC X 100GM
Manufacturer reference
528877-100GM
CHU nomenclature
18,552
IRSN nomenclature
273
Sold by
100 g
CNRS nomenclature
NA28
Customer error recovery
No



SAFETY INFORMATION ABOUT POLYETHYLENE GLYCOL 10000
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


POLYETHYLENE GLYCOL 12 CETOSTEARYL ETHER
Polyethylene Glycol 12 Cetostearyl Ethers are products of condensed ethylene oxide and water that can have various derivatives and functions.
Polyethylene Glycol 12 Cetostearyl Ether is a non-ionic hydrophilic polymer and is available in different molecular weights.
Polyethylene Glycol 12 Cetostearyl Ether is a compound derived from cetyl and stearyl alcohols.

CAS Number: 27879-07-8
Molecular Formula: (C2H4O)nC2H6O

Polyethylene Glycol 12 Cetostearyl Ether helps in the purification and crystal growth of proteins and nucleic acids.
Polyethylene Glycol 12 Cetostearyl Ether and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials.

Polyethylene Glycol 12 Cetostearyl Ether also interacts with cell membrane, thereby allowing cell fusion.
Polyethylene Glycol 12 Cetostearyl Ether is a mixture of ethers of mixed polyethylene glycols with linear fatty alcohols, mainly cetostearyl alcohol.
Polyethylene Glycol 12 Cetostearyl Ether may contain some free polyethylene glycols and various amounts of free cetostearyl alcohol.

The number of moles of ethylene oxide reacted per mole of cetostearyl alcohol is 12 (nominal value).
Polyethylene Glycol 12 Cetostearyl Ether is a compound used in the formulation of cosmetic and personal care products.
Polyethylene Glycol 12 Cetostearyl Ether is part of the larger family of polyethylene glycol (PEG) ethers.

Polyethylene Glycol 12 Cetostearyl Ether can be used as an excipient.
Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients.
Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations.

Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs.
Polyethylene Glycol 12 Cetostearyl Ether, a United States Pharmacopeia (USP) Reference Standard known for its unparalleled reliability and adherence to stringent US Pharmacopeia guidelines.
This ether stands out for its consistent performance, minimal impurities, and strict quality assurance, making it an indispensable component in the pharmaceutical industry.

Cetomacrogol 1000 is the tradename for Polyethylene Glycol 12 Cetostearyl Ether, which is nonionic surfactant produced by the ethoxylation of cetyl alcohol to give a material with the general formula HO(C2H4O)nC16H33.
Several grades of this material are available depending on the level of ethoxylation performed, with repeat units (n) of polyethylene glycol varying between 2 and 20.
Commercially it can be known as Brij 58 (when n=20) or Brij 56 (when n=10). Brij is a trademark of Croda International.

Polyethylene Glycol 12 Cetostearyl Ether is used as a solubilizer and emulsifying agent in foods, cosmetics, and pharmaceuticals, often as an ointment base.
Polyethylene Glycol 12 Cetostearyl Ether is used as an oil in water (O/W) emulsifier for creams/lotions, and a wetting agent.
Polyethylene Glycol 12 Cetostearyl Ether can be used as an excipient.

Polyethylene Glycol 12 Cetostearyl Ether is a polymer of ethylene oxide, and it is commonly used in the cosmetic and pharmaceutical industries.
Polyethylene Glycol 12 Cetostearyl Ether's known for its emollient and humectant properties, helping to soften and moisturize the skin.

These alcohols are fatty alcohols that are often obtained from natural sources like coconut or palm oil.
Polyethylene Glycol 12 Cetostearyl Ether is used in cosmetics and personal care products for its emollient properties, which contribute to the product's texture and skin-feel.
Polyethylene Glycol 12 Cetostearyl Ether is a polymer with the chemical formula HO(CH2CH2O)nH.

Polyethylene Glycol 12 Cetostearyl Ether is properties vary according to its molecular weight, from a colourless and odourless viscous liquid to a waxy solid.
Polyethylene Glycol 12 Cetostearyl Ether is a liquid at room temperature with a molecular weight of 200 to 600, and gradually becomes a semi-solid with a molecular weight above 600, with different properties depending on the average molecular weight.
From colourless and odourless viscous liquids to waxy solids.

As the molecular weight increases, its hygroscopic capacity decreases accordingly.
Polyethylene Glycol 12 Cetostearyl Ether is soluble in water, ethanol and many other organic solvents.
Polyethylene Glycol 12 Cetostearyl Ether has a low vapour pressure and is stable to heat, acids and bases.

Polyethylene Glycol 12 Cetostearyl Ether does not interact with many chemicals.
Polyethylene Glycol 12 Cetostearyl Ether has good hygroscopicity, lubricity and bonding properties.
In emulsion-based products, such as creams and lotions, Polyethylene Glycol 12 Cetostearyl Ether aids in balancing the oil and water phases.

This is crucial for the stability and uniformity of the product.
Polyethylene Glycol 12 Cetostearyl Ether is generally considered mild and non-irritating, making it suitable for use in products intended for individuals with sensitive skin.
Polyethylene Glycol 12 Cetostearyl Ether is often included in hair conditioning products such as leave-in conditioners and hair masks.

Polyethylene Glycol 12 Cetostearyl Ether is emollient properties contribute to detangling and smoothing the hair.
The emollient nature of the compound helps provide long-lasting moisturization to the skin, contributing to the overall hydration and comfort of the user.

In some formulations, Polyethylene Glycol 12 Cetostearyl Ether may assist in the delivery of other active ingredients, ensuring their effective absorption into the skin or hair.
Due to its versatility, Polyethylene Glycol 12 Cetostearyl Ether is used in a diverse range of product formulations, allowing formulators to create products with different textures, consistencies, and performance characteristics.

Melting point: 255 °C
EPA Substance Registry System: Poly(oxy-1,2-ethanediyl), .alpha.-ethyl-.omega.-hydroxy- (27879-07-8)

Polyethylene Glycol 12 Cetostearyl Ether is white granular.
Soluble in water, soluble in some organic solvents.
Polyethylene Glycol 12 Cetostearyl Ether is solution has high viscosity at low concentration, and can be processed by calendering, extrusion, casting, etc.

Polyethylene Glycol 12 Cetostearyl Ether is a thermoplastic resin with good compatibility with other resins.
Polyethylene Glycol 12 Cetostearyl Ether is resistant to bacterial erosion and has weak hygroscopicity in the atmosphere.
Polyethylene Glycol 12 Cetostearyl Ether may contribute to the foaming properties of a product.

This is particularly relevant in products such as facial cleansers and body washes, where a foaming action is desirable for cleansing.
Polyethylene Glycol 12 Cetostearyl Ether is known for its ability to improve the spreading properties of cosmetic formulations.
This ensures that the product is easy to apply and distribute evenly on the skin or hair.

Depending on the concentration used, Polyethylene Glycol 12 Cetostearyl Ether may contribute to the viscosity (thickness) of a product.
This can be beneficial in achieving the desired texture, especially in formulations like creams and lotions.
In some sunscreen formulations, Polyethylene Glycol 12 Cetostearyl Ether may be included.

Polyethylene Glycol 12 Cetostearyl Ether is emollient and stabilizing properties can contribute to the overall sensory experience of a sunscreen product.
The emollient nature of this compound can contribute to the soothing and calming properties of a product, making it suitable for formulations targeting sensitive or irritated skin.
Polyethylene Glycol 12 Cetostearyl Ether is commonly found in various makeup products such as foundations, BB creams, and concealers.

Polyethylene Glycol 12 Cetostearyl Ether is emollient and spreading properties contribute to the smooth application of these products.
Polyethylene Glycol 12 Cetostearyl Ether is a compound, its series of products are non-irritating, slightly bitter in taste, have good water solubility, and have good compatibility with many organic components.
They have excellent lubricity, moisture retention, dispersibility, adhesive, antistatic agent and softener, etc.

They are used in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food processing, etc.
Polyethylene Glycol 12 Cetostearyl Ether is often found in cleansing products such as facial cleansers, body washes, and shampoos.
Polyethylene Glycol 12 Cetostearyl Ether is surfactant properties contribute to the formation of stable emulsions and help in the removal of dirt and impurities from the skin and hair.

In hair care formulations, Polyethylene Glycol 12 Cetostearyl Ether can contribute to the conditioning and smoothing of the hair.
Polyethylene Glycol 12 Cetostearyl Ether is commonly found in shampoos, conditioners, and styling products.
Due to its emollient and stabilizing properties, Polyethylene Glycol 12 Cetostearyl Ether is frequently used in the formulation of creams and lotions.

Polyethylene Glycol 12 Cetostearyl Ether helps create products with a desirable texture, providing a smooth and moisturizing feel upon application.
Polyethylene Glycol 12 Cetostearyl Ether is known for its compatibility with a wide range of other cosmetic ingredients.
This makes it a versatile choice for formulators who seek to create products with various active ingredients and sensory attributes.

In addition to its functional properties, Polyethylene Glycol 12 Cetostearyl Ether can enhance the overall feel of a product.
Polyethylene Glycol 12 Cetostearyl Ether contributes to the sensory experience, making the product more pleasant to use.
In some formulations, Polyethylene Glycol 12 Cetostearyl Ether may be used in combination with other surfactants to achieve specific cleansing or foaming characteristics in a product.

The emollient nature of the compound helps in maintaining skin hydration by preventing water loss.
Polyethylene Glycol 12 Cetostearyl Ether can also contribute to the formation of a protective barrier on the skin, enhancing its overall condition.
Polyethylene Glycol 12 Cetostearyl Ether is suitable for both leave-on and rinse-off products, offering flexibility in formulating various types of cosmetic and personal care items.

Cosmetic ingredients, including Polyethylene Glycol 12 Cetostearyl Ether, are subject to regulatory standards and safety assessments.
Formulations are designed to comply with these regulations to ensure consumer safety.
Polyethylene Glycol 12 Cetostearyl Ether is used globally in a wide range of cosmetic and personal care products, contributing to the formulation of products with consistent quality and performance.

Polyethylene Glycol 12 Cetostearyl Ether helps to soften and smooth the skin, contributing to the overall sensory experience of a cosmetic or personal care product.
Polyethylene Glycol 12 Cetostearyl Ether compounds are known for their humectant properties, meaning they can attract and retain moisture. This can help improve the hydration of the skin.
The compound can contribute to the stability of emulsions (mixtures of oil and water) in formulations, preventing them from separating over time.

Depending on its concentration, Polyethylene Glycol 12 Cetostearyl Ether may act as a surfactant, helping to reduce the surface tension between different phases in a formulation.
This is particularly relevant in products like creams and lotions where oil and water need to be combined.

Uses:
Polyethylene Glycol 12 Cetostearyl Ether can be used as a medium for organic synthesis and a heat carrier with high requirements.
Polyethylene Glycol 12 Cetostearyl Ether is used as a humectant, inorganic salt solubilizer and viscosity adjuster in the daily chemical industry; as a softener and antistatic agent in the textile industry; as a wetting agent in the paper and pesticide industry.
Polyethylene Glycol 12 Cetostearyl Ether is used to contribute to the texture and consistency of cosmetic formulations.

Polyethylene Glycol 12 Cetostearyl Ether aids in the even distribution of the product and enhances its spreadability.
Polyethylene Glycol 12 Cetostearyl Ether is most suitable for softgels.
Polyethylene Glycol 12 Cetostearyl Ether is a liquid, it has a wide range of compatibility with various solvents and is a good solvent and solubiliser, and is widely used in liquid formulations, such as oral liquids and eye drops.

Polyethylene Glycol 12 Cetostearyl Ether serves as an emollient, helping to soften and smooth the skin.
Polyethylene Glycol 12 Cetostearyl Ether is commonly found in moisturizers, creams, and lotions, contributing to the overall skin-feel and hydration.
Polyethylene Glycol 12 Cetostearyl Ether can act as a surfactant in cleansing products such as facial cleansers, body washes, and shampoos.

Polyethylene Glycol 12 Cetostearyl Ether helps in the removal of dirt, oils, and impurities from the skin and hair.
Polyethylene Glycol 12 Cetostearyl Ether is often used to stabilize emulsions, especially in formulations where oil and water need to be combined.
This is crucial for maintaining the stability and uniformity of products like creams and lotions.

Polyethylene Glycol 12 Cetostearyl Ether contributes to the texture of cosmetic products, providing a smooth and creamy consistency.
This is desirable in formulations like foundations, BB creams, and concealers.
In hair care products such as conditioners and leave-in treatments, Polyethylene Glycol 12 Cetostearyl Ether helps condition the hair, making it more manageable, smooth, and easy to comb.

In formulations like facial cleansers and body washes, Polyethylene Glycol 12 Cetostearyl Ether may contribute to the foaming properties, providing a pleasant and satisfying cleansing experience.
Polyethylene Glycol 12 Cetostearyl Ether can serve as a thickening agent in certain formulations, helping to achieve the desired viscosity of products like creams and lotions.
The humectant properties of this compound contribute to the hydration of the skin.

Polyethylene Glycol 12 Cetostearyl Ether attracts and retains moisture, helping to keep the skin supple.
Polyethylene Glycol 12 Cetostearyl Ether is often included in various makeup products, including foundations, primers, and other cosmetic formulations.
Polyethylene Glycol 12 Cetostearyl Ether helps create products with a smooth application and desirable texture.

Due to its emollient and stabilizing properties, it may be included in the formulation of sunscreens, contributing to the product's texture and overall performance.
Polyethylene Glycol 12 Cetostearyl Ether is suitable for both leave-on and rinse-off products, offering versatility in formulating a wide range of cosmetic and personal care items.
Polyethylene Glycol 12 Cetostearyl Ether enhances the spreading properties of products, ensuring even application on the skin or hair.

Being generally mild and non-irritating, Polyethylene Glycol 12 Cetostearyl Ether is suitable for use in products targeted for individuals with sensitive or easily irritated skin.
Polyethylene Glycol 12 Cetostearyl Ether is the material of choice when vegetable oils are not suitable as a carrier for active ingredients.
Polyethylene Glycol 12 Cetostearyl Ether is used as a base or lubricant and softener in the pharmaceutical, textile and cosmetic industries; used as a dispersant in the paint industry to improve the water dispersibility and flexibility of resins, with a dosage of 10-30%; used to improve the solubility of dyestuffs and reduce their volatility in printing ink, especially in wax paper and printing ink, also used to adjust the consistency of ink in biros ink.

Polyethylene Glycol 12 Cetostearyl Ether is also used as a dispersant in the rubber industry to promote vulcanisation and as a dispersant for carbon black filling materials.
Polyethylene Glycol 12 Cetostearyl Ether is used as metal processing casting agent, lubricant and cutting fluid for metal drawing, stamping or forming, grinding cooling lubricating polishing agent, welding agent, etc.; used as lubricant in paper industry, etc., also used as hot melt adhesive to increase fast rewetting ability.
Included in facial moisturizers, Polyethylene Glycol 12 Cetostearyl Ether helps provide hydration and contributes to the overall texture of the product, offering a smooth and moisturizing experience for the skin.

This ingredient is commonly found in hand creams and lotions, contributing to the formulation's ability to soften and moisturize the skin on the hands.
Polyethylene Glycol 12 Cetostearyl Ether is used in body creams and body butters, it enhances the emollient properties of the formulation, leaving the skin feeling soft and nourished.
Polyethylene Glycol 12 Cetostearyl Ether may be included in anti-aging products such as serums and creams, contributing to the overall feel and performance of these formulations.

Polyethylene Glycol 12 Cetostearyl Ether is emollient properties make it suitable for inclusion in shaving creams and gels, providing a smooth glide during shaving while helping to hydrate the skin.
In addition to foaming cleansers, Polyethylene Glycol 12 Cetostearyl Ether can be used in cleansing lotions, offering a gentle and hydrating cleansing experience.
Included in after-sun lotions and creams, it can help soothe and moisturize the skin after sun exposure.

Found in baby lotions and creams, Polyethylene Glycol 12 Cetostearyl Ether contributes to formulations designed for the delicate skin of infants.
In deodorants and antiperspirants, this ingredient may be used to enhance the product's feel and spreadability on the skin.
Polyethylene Glycol 12 Cetostearyl Ether is used in foot creams, it contributes to the moisturizing and softening properties of the product, addressing dryness and roughness on the feet.

Included in cosmetic primers, Polyethylene Glycol 12 Cetostearyl Ether can help create a smooth base for makeup application, contributing to a flawless finish.
Polyethylene Glycol 12 Cetostearyl Ether may be found in certain fragrance formulations, contributing to the overall texture of scented products.
In formulations designed for intimate care, this ingredient may contribute to the moisturizing and soothing properties of the product.

Polyethylene Glycol 12 Cetostearyl Ether is used in tinted moisturizers, it helps in creating a product that not only provides hydration but also contributes to an even and smooth application of color.
Included in various serums and treatment products, it can enhance the overall feel and performance of targeted skincare formulations.
Polyethylene Glycol 12 Cetostearyl Ether good coating material, hydrophilic polishing material, film and capsule material, plasticizer, lubricant and drip matrix for the preparation of tablets, pills, capsules, microcapsules, etc.

Polyethylene Glycol 12 Cetostearyl Ether is used as a finishing agent in the paper industry to increase the gloss and smoothness of paper; as an additive in the rubber industry to increase the lubricity and plasticity of rubber products, reduce the power consumption during processing and extend the service life of rubber products.
Polyethylene Glycol 12 Cetostearyl Ether is commonly used in various cosmetic and personal care products such as creams, lotions, moisturizers, and hair care products.

Safety Profile:
In some individuals, particularly those with sensitive skin, there is a possibility of skin irritation.
This can manifest as redness, itching, or other forms of skin discomfort.
Polyethylene Glycol 12 Cetostearyl Ether's advisable to perform patch tests, especially for individuals prone to skin sensitivities.

Contact with the eyes may cause irritation.
In case of accidental contact, thorough rinsing with water is recommended.
Protective measures, such as avoiding direct contact with the eyes, should be taken.

Some people may be allergic to specific ingredients in cosmetic formulations, including Polyethylene Glycol 12 Cetostearyl Ether.
Allergic reactions can vary and may include redness, swelling, or itching.
Inhalation of dust or aerosolized particles of cosmetic ingredients, including Polyethylene Glycol 12 Cetostearyl Ether, should be avoided.

Contamination of cosmetic products can occur if proper hygiene and storage practices are not followed.
This can lead to the growth of microorganisms, potentially causing skin infections.
Users should ensure the cleanliness of products and storage containers.

Synonyms:
27879-07-8
Brij-58
2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-hexadecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
PEG 20 cetostearyl ether
DTXSID7046708
NCGC00167551-01
198563-32-5
CETOMACROGOL
Polyethylene Glycol 12 Glyceryl Laurate
Polyetheramine; polypropylene glycol based polyetheramine cas no: 9046-10-0
POLYETHYLENE GLYCOL 1500
The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups.
The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides.
The average molecular weight of any specific Polyethylene glycol 1500 product falls within quite narrow limits (°5%).

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

Polyethylene glycol 1500 is completely soluble in water with low toxicity and is molecularly stable and non-volatile.
Polyethylene glycol 1500 is a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene.
The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups.
The number of ethylene oxide units or their approximate molecular weight (e.g., PEG-4 or PEG-200) commonly designates the nomenclature of specific polyethylene glycols.
Polyethylene glycols with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid.

Polyethylene glycol 1500 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: Polyethylene glycol 1500(25322-68-3)
EPA Substance Registry System: Polyethylene glycol 1500 (25322-68-3)

Application in biomedicine
Polyethylene glycol 1500 is also known as polyoxirane (PEO).
Polyethylene glycol 1500 is a linear polyether obtained by ring opening polymerization of ethylene oxide.
The main uses in the field of biomedicine are as follows:
Contact lens liquid.
The viscosity of Polyethylene glycol 1500 is sensitive to the shear rate and it is not easy for bacteria to grow on polyethylene glycol.
Synthetic lubricants.
The condensation polymer of ethylene oxide and water.
Polyethylene glycol 1500 is a cream matrix for preparing water-soluble drugs.
Polyethylene glycol 1500 can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.
Drug sustained-release and immobilized enzyme carrier.
The Polyethylene glycol 1500 is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
Surface modification of medical polymer materials.

The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing polyethylene glycol on the surface of medical polymers.
Polyethylene glycol 1500 can make the membrane of the alkanol contraceptive pill.
Polyethylene glycol 1500 can make hydrophilic anticoagulant polyurethane.
Polyethylene glycol 1500 is an osmotic laxative.
Polyethylene glycol 1500 can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
Denture fixing agent.
Peg nontoxic and gelatinous nature can be used as a component of denture fixer.
PEG 4000 and PEG 6000 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation.
Polyethylene glycol 1500 absorbs water from the solution, so it is also used to concentrate the solution.

Production Methods
Polyethylene glycol 1500 polymers are formed by the reaction of ethylene oxide and water under pressure in the presence of a catalyst.
Polyethylene glycol 1500 was obtained by polymerization of ethylene oxide in an autoclave at 80-100°C using as a catalyst dipotassium alcogolate of polyethylene glycol 400.
Dipotassium alcogolate of polyethylene glycol 1500 was synthesized by a heating of the dry mixture of polyethylene glycol 1500 and potassium hydroxide.
The molecular weight of polymer was regulated by the ratio of monomer:catalyst.
POLYETHYLENE GLYCOL 1500
PEG 1500 Applications PEG 1500 Application Polyethylene glycol 1500 for synthesis. CAS 25322-68-3, pH 4 - 7 (100 g/l, H₂O, 20 °C). PEG 1500 Physicochemical Information PEG 1500 Boiling point >200 °C (1013 hPa) PEG 1500 Density 1.2 g/cm3 (20 °C) PEG 1500 Flash point 240 °C PEG 1500 Ignition temperature 420 °C PEG 1500 Melting Point 43 - 49 °C PEG 1500 pH value 4 - 7 (100 g/l, H₂O, 20 °C) PEG 1500 Vapor pressure <0.01 hPa (20 °C) PEG 1500 Bulk density 400 - 500 kg/m3 PEG 1500 Solubility 650 g/l PEG 1500 Toxicological Information PEG 1500 LD 50 oral LD50 Rat 28000 mg/kg PEG 1500 LD 50 dermal LD50 Rabbit > 20000 mg/kg PEG 1500 Safety Information according to GHS PEG 1500 Storage class 10 Combustible liquids PEG 1500 WGK WGK 1 slightly hazardous to water PEG 1500 Disposal 3 PEG 1500 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. PEG 1500 Storage and Shipping Information PEG 1500 Storage Store below +30°C. PEG 1500 Transport Information PEG 1500 Declaration (railroad and road) ADR, RID Kein Gefahrgut PEG 1500 Declaration (transport by air) IATA-DGR No Dangerous Good PEG 1500 Declaration (transport by sea) IMDG-Code No Dangerous Good PEG 1500 Specifications PEG 1500 Melting range (lower value) ≥ 43 °C PEG 1500 Melting range (upper value) ≤ 49 °C PEG 1500 Hydroxyl value 70 - 80 PEG 1500 Average molecular mass 1400 - 1600 PEG 1500 Identity (IR) passes test Activated PEG 1500s (for conjugation to biologics) PEG 1500-PLA or PEG 1500-PLGA (for nanoparticle formulations of drugs) Linear and branched functionalized polyethylene imines and other polyimines (for oligo-nucleotide binding and delivery) PEG 1500-pAsp / PEG 1500-pGlu (for oligo-nucleotide binding and delivery) Hyperbranched polyglycerols (for drug delivery and protein formulation) Other polymers for nanoparticle formation (drug delivery) Poly(ethylene glycol) (PEG 1500) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG 1500 and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG 1500 also interacts with cell membrane, thereby allowing cell fusion.Polyethylene Glycol 1500 (PEG 1500-1500) has been used to mediate cell fusion.PEG 1500 is a polymer of ethylene oxide with an average molecular weight of 1500. This polymeric material is an excellent solubiliser and can be used in a wide variety of home care and I&I applications.Polyethylene glycol. PEG- 1500 by Dynamic International is a surfactant. It is available in the form of milky white solid. PEG- 1500 is used in cream and shampoo base material.Crystallization grade Polyethylene glycol 1500(PEG 1500) for formulating screens or for optimization.PEG 1500 Eye contact Unlikely to cause eye irritation in man.PEG 1500 Skin contact Unlikely to cause skin irritation in man.PEG 1500 Inhalation This material may cause irritation following inhalation.PEG 1500 Ingestion Will cause irritation of the gastrointestinal tract.Low oral toxicity, but ingestion may cause irritation of the gastrointestinal tract.PEG 1500 Eye contact Irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.PEG 1500 Skin contact Remove contaminated clothing. Wash skin with soap and water. If symptoms develop, obtain medical attention.PEG 1500 Inhalation Remove patient from exposure. Obtain medical attention if ill effects occur.PEG 1500 Ingestion Do not induce vomiting. Wash out mouth with water and give 200-300 ml (half a pint) of water to drink. Obtain medical attention if ill effects occur.PEG 1500 Further Medical Treatment Symptomatic treatment and supportive therapy as indicated.PEG 1500 Extinguishing Media Water fog, alcohol foam, carbon dioxide, dry chemical.PEG 1500 Unsuitable Extinguishing Media None known.PEG 1500 Special fire-fighting protective equipment A self contained breathing apparatus and suitable protective clothing must be worn in fire conditions.PEG 1500 Fire and explosion hazards Combustible but not readily ignited. PEG 1500 Colour white PEG 1500 Form solid PEG 1500 Odour mild PEG 1500 pH approx 5 - 7 5% In water PEG 1500 Boiling point/boiling range (°C) No data. PEG 1500 Flash Point (ºC) > 260 (open cup) PEG 1500 Autoignition Temperature (ºC) approx 420 PEG 1500 Flammable Limits No data. PEG 1500 Explosive Properties No data. PEG 1500 Oxidising Properties No data. PEG 1500 Vapour Density No data. PEG 1500 Solubility in water soluble PEG 1500 Solubility in other ingredients Soluble in many organic solvents, insoluble in:, aliphatic hydrocarbons PEG 1500 Partition Coefficient No data. PEG 1500 Dynamic viscosity (mPa.s) approx 30 @99°C PEG 1500 Density (g/ml) 1.208 @ 20 °C PEG 1500 Stability Stable under normal conditions. PEG 1500 Materials to avoid Strong oxidising agents. PEG 1500 Conditions to avoid None known PEG 1500 Hazardous decomposition products None known PEG 1500 Hazardous polymerisation Will not occur
POLYETHYLENE GLYCOL 200
Polyethylene glycol 200 a structure-directing agent to synthesize iron vanadate (FeVO4) nanoparticles via co-precipitation method.
Polyethylene glycol 200 an organic additive to prepare crystalline nanorods of calcium tungstate (CaWO4) using calcium chloride and sodium tungstate via solvothermal process.
Polyethylene glycol 200 a surface modifier in the synthesis of calcium peroxide nanoparticles using CaCl2 as a precursor via hydrolysis-precipitation method.

CAS Number: 25322-68-3
EINECS Number: 500-038-2

Synonyms: Polyethylene Glycol 200, PEG 200, PEG-200, R95B8J264J, 203-989-9, MACROGOL 200, polyox FRA, 1,11-DIHYDROXY-3,6,9-TRIOXAUNDECANE, 1,2-ETHANEDIOL, HOMOPOLYMER, 1660O, 1660S, ALKOX, ALKOX E 30, ALPHA-HYDRO-OMEGA-HYDROXYPOLY(OXY-1,2-ETHANEDIYL)POLYOXYETHYLENEDIOL), CARBOWAX E 9000, CARBOWAX PEG 200, CBP 20, CERASOL 250A, CHEMIOX E 20(C), DB-WAX, DECUFLUX RM 33, DESMOPHEN L 1208, E 1450NF, E 200 (POLYGLYCOL), E 400NF, EMKAPOL 150, EMKAPOL 200, ETHYLENE OXIDE, HOMOPOLYMER, ETHYLENE POLYOXIDE, GAFANOL E 300, GENOPLAST 200, IW (DISPERSANT), KLEANPREP, LAPROL 1001, LAPROL 402, LINEARTOP P, LIPO POLYGLYCOL 200, LUMULSE PEG 200, LUTROL 9, M 9000, MACOL E 300, MACROGOL 400R, MICROSOLV PEG 100, NOPCOFLOC 310, NSC-1262, OEG, OEG 100, OEG 2000, OEG 300, OXIDE A, OXIDE WAX A, OXIRANE, HOMOPOLYMER, P 300 (POLYOXYALKYLENE), PE 68, PE 68 (POLYOL), PEG (POLYGLYCOL), PEG 115, PEG 20000, PEG 2M, PEG 35, PEG 4, PEG 4000N, PEG 4600, PEG 5000, PEG 6, PEG 6000S, PEG 75, PEO 1, PEO 10, PEO 100, PEO 15, PEO 16, PEO 18, PEO 3, PEO 5000, PEO 8, PEOPO-A, PLASTIGEN PR 8086, PLURACARE E 200, PLURACOL E 300, PLURACOL E 4600, PLURIOL 9000, PLURIOL E, PLURIOL E 2000, PLURIOL E 300, PLURIOL E 9000, POLIKOL, POLIKOL 1600, POLIKOL 300, POLIKOL 3T, POLY(ETHYLENE ETHER) GLYCOL, POLY(OXYETHYLENE) GLYCOL, POLY(VINYL OXIDE), POLYDIOL 1550, POLYDIOL 200, POLYDIOL 300, POLYETHYLENE GLYCOL 200 (II), POLYETHYLENE GLYCOL 200 (USP-RS), POLYGLYCOL 12000, POLYGLYCOL 300, POLYGLYKOL 200, POLYGOL, POLYHYDROXYETHYLENE, POLYOX (POLYGLYCOL), POLYOX 1, POLYOX 100, POLYOX 30, POLYOX 303, POLYOX 309, POLYOX 600K, POLYOX COAGULANT, POLYOX N 10, POLYOX N 12K, POLYOX N 3000, POLYOX N 60K, POLYOX N 750, POLYOX N 78, POLYOX N 80, POLYOX OF 50, POLYOX UCARFLOC 309, POLYOX WRN 3000, POLYOX WRPA 3154, POLYOX WSR, POLYOX WSR 1105, POLYOX WSR 205, POLYOX WSR 303, POLYOX WSR 31, POLYOX WSR 35, POLYOX WSR 700, POLYOX WSR 80, POLYOX WSR-FRA, POLYOX WSR-N 10, POLYOX WSR-N 12K, POLYOX WSR-N 205, POLYOX WSR-N 3000, POLYOX WSR-N 301, POLYOX WSR-N 303, POLYOX WSR-N 3333, POLYOX WSR-N 60K, POLYOX WSR-N 750, POLYOX WSR-N 78, POLYOX WSR-N 80, POLYOX WSR-N 80-1001C, POLYOXYALKYLENES, POLYETHYLENE GLYCOL, POLYOXYDIN, POLYOXYETHYLENEDIOL, POLYWAX 12000, POLYWAX 20000, POSTONAL, PT-C 300ZT, PT-T 8-200DL, REXOL P 2002, SABOPEG 200, SOLBASE, SS 70, ST 836, SUPEROX 0.1, SUPEROX 0.6, SUPEROX 4, SUPEROX 5, SURFONYL, SWASCONOL D 60, SWASCONOL D 80, TEISAN Z 75, TENZILIN 200, TENZILIN 300, TOHO PEG NO. 200, U 100 (POLYGLYCOL), UCAR 4C, UCARFLOC, ULTRAFLOC 309, UNIPEG-200 X, UPIWAX 200, VITERRA 2 HYDROGEL, WSR 205, WSR 301, WSR 35, WSR-N 10, WSR-N 3000, WSR-N 750, WSR-N COAG, ZUSOPLAST 9002

Polyethylene glycol 200 a green solvent in combination with H2O in the preparation of 4-sulfanylcoumarins by sulfanylation of 4-tosyloxycoumarins with thiourea and alkyl halides
Polyethylene glycol 200 is a type of polyethylene glycol, which is a polymer made from ethylene oxide and water.
Polyethylene glycol 200 is strongly hydrophilic.

The partition coefficient of Polyethylene glycol 200 between hexane and water is 0.000015 (log𝑃=−4.8{\displaystyle P=-4.8}), indicating that when Polyethylene glycol 200 is mixed with water and hexane, there are only 15 parts of Polyethylene glycol 200 in the hexane layer per 1 million parts of PEG 400 in the water layer.
Polyethylene glycol 200 is a low-molecular-weight grade of polyethylene glycol.
Polyethylene glycol 200 is a clear, colorless, and odorless liquid that is used in a variety of applications due to its properties as a solvent, plasticizer, surfactant, and lubricant.

Polyethylene glycol 200 is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.
Polyethylene glycol 200 (PEG-200, polyethylene glycol monostearate) is a polyether compound with the chemical structure H−(O−CH2−CH2)n−OH.
Polyethylene glycol 200 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons.

Polyethylene glycol 200 is not miscible with aliphatic hydrocarbons and diethyl ether.
Therefore, reaction products can be extracted from the reaction media with those solvents.
Polyethylene glycol 200 is a polymer which is hydrolyzed by ethylene oxide.

Polyethylene glycol 200 has no toxicity and irritation.
Polyethylene glycol 200 is widely used in various pharmaceutical preparations.
The toxicity of low molecular weight Polyethylene glycol 200 is relatively large.

In general, the toxicity of diols is very low.
Polyethylene glycol 200 is a non-ionic hydrophilic polymer and is available in different molecular weights.

Polyethylene glycol 200 either exists in the form of a linear or branched structure.
Polyethylene glycol 200 aids in the purification and crystal growth of proteins and nucleic acids.

Polyethylene glycol 200 along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials.
Polyethylene glycol 200 permits cell fusion through its interaction with the cell membrane.
Polyethylene glycol 200 has been used in the production of monoclonal antibodies.

Polyethylene glycol 200, NF acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.
All SpectrumPolyethylene glycol 200 grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP).
The low-molecular weight liquid Polyethylene glycol 200 is an excellent solvent for a large number of substances that do not readily dissolve in water.

Topical application of Polyethylene glycol 200, especially mucosal drug, can cause irritant pain.
In topical lotion, Polyethylene glycol 200 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
Diarrhoea can occur in large doses of oral administration.

In injection, the maximum Polyethylene glycol 200 concentration is about 30% (V/V).
Traditionally, Polyethylene glycol 200 is derived from petroleum-based sources.
Acme-Hardesty is proud to offer a completely renewable PEG-200 that is Bio-based.

One of our many sustainable alternatives to conventional industrial chemicals, our Polyethylene glycol 200 is an ideal choice for a wide range of industrial applications.
Polyethylene glycol 200 has a wide range of potential uses.
It is a defoaming agent, lubricant and viscosity modifier in many different products.

Polyethylene glycol 200 is also used as a coating for fresh fruit, as a solvent in metal working fluids, as a binder and modifier in latex paints, and as a humectant in inks and abrasives.
Specific industries that rely on PEG-200 include cosmetics, health and medicine, textiles and more.
For a detailed list of potential applications, or for assistance determining whether or not Polyethylene glycol 200 can be used for your product, contact Acme-Hardesty today.

Polyethylene glycol 200 is a clear, slightly viscous liquid, a polymer of ethylene glycol with an average molecular weight of 200 g/mol.
Polyethylene glycol 200 is a compound with a wide range of applications.
Polyethylene glycol 200 has wetting, dissolving, dispersing and stabilizing properties.

In metalworking, polyethylene glycol 200 is used as a solvent in welding fluxes.
Polyethylene glycol 200 can be used both in the production of the fluxes themselves, as a base for dissolving/solubilizing components, and in the cleaning of welding fluxes after welding.
In cosmetics, Polyethylene Glycol 200 is used as a non-toxic humectant (often in combination with glycerin to obtain a synergistic effect), as a solvent in a variety of creams and lotions, since it acts as a non-ionic surfactant.

Polyethylene glycol 200 can also be used as a base for lotions, transparent creams, or massage products such as lotions, creams, or massage products.
Bath gels or bath bombs, because of its lubricating/slip-enhancing properties.
In the manufacture of soaps or detergents, it is used as a viscosity modifier/thickener, which helps to thicken products without the use of surfactants.

In the manufacture of toothpastes, Polyethylene glycol 200 is used as a stabilizer to help keep the water evenly distributed and the xanthan gum evenly distributed throughout the toothpaste volume.
Moisture-retaining agent: maintains the water content of the cosmetic product both in the packaging and on the skin.
Polyethylene glycol 200, commonly known as PEG 200, is a low-molecular-weight variant of PEG, widely used in pharmaceuticals, cosmetics, and industrial applications for its excellent solubility and lubricating properties.

Polyethylene glycol 200 is characterized by its hydrophilic nature, making it an ideal ingredient for formulations requiring water solubility and lubrication.
Polyethylene glycol 200 has a relatively low freezing point and a high boiling point, making it stable and effective over a wide temperature range.
It is highly soluble in water and many organic solvents, and its chemical stability makes it suitable for various formulations.

Polyethylene glycol 200, commonly known as PEG 200, is a highly adaptable and stable product that is essential in many diverse industries for its lubricating and hydrating properties.
Polyethylene glycol 200 is a key component in many different applications including industrial, lubricants, adhesives, pharmaceuticals and personal care products.
Polyethylene glycol 200 is used as a binder in the preparation of technical ceramics.

Polyethylene glycol 200 is the basis of many skin creams (as cetomacrogol) and personal lubricants (often combined with glycerin).
Polyethylene glycol 200 is used as a dispersant in a number of toothpastes.

In this application, Polyethylene glycol 200 binds water and helps keep the xanthan gum evenly distributed throughout the toothpaste.
Polyethylene glycol 200 is also being researched in body armor and tattoos used to monitor diabetes.
Polyethylene glycol 200 belongs to the group of polyoxyethylene glycols.

Polyethylene glycol 200 is a colourless liquid, well soluble in water.
Polyethylene glycol 200 is characterized by strong hygroscopic properties.
Polyethylene glycol 200 exhibits excellent dissolution capacity of the active ingredients.

Polyethylene glycol 200 is characterized by a wide range of applications.
Polyethylene glycol 200 has excellent softening, lubricating, solubilizing, moisturizing and anti-electrostatic properties.
Polyethylene glycol 200 is a polyether compound derived from petroleum with many applications from industrial production to pharmaceuticals.

Polyethylene glycol 200 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE) depending on its molecular weight.
The Polyethylene glycol 200 structure is usually expressed as H−(O−CH2−CH2) n−OH.
Polyethylene glycol 200 is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.

Polyethylene glycol 200 is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Polyethylene glycol 200 is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye.
Polyethylene glycol 200 indicates that the average molecular weight of the specific PEG is 400.

Polyethylene glycol 200 is a clear liquid with an average molecular weight of 400.
Polyethylene glycol 200 is soluble in water and other polar organic solvents.
Polyethylene glycol 200 is useful in a wide variety of applications including lubricants, plastics, paper, pharmaceuticals, personal care, and food industries.

Polyethylene glycol 200 is useful as a viscosity modifier, plasticizer, and heat transfer agent in many industrial applications.
Because it its humectant properties, Polyethylene glycol 200 can be used in many personal care formulations for ointments and creams.
Polyethylene glycol 200 is also used in gelatin capsules as liquid carriers.

Because of Polyethylene glycol 200’s hydroxyl groups, it can also be used as a chemical intermediate.
The low-molecular weight liquid Polyethylene glycol 200 is an excellent solvent for a large number of substances that do not readily dissolve in water.
They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations.

Polyethylene glycol 200 is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power.
Polyethylene glycol 200 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances.
Polyethylene glycol 200 is widely used in a variety of pharmaceutical formulations.

Polyethylene glycol 200 can be used as: A structure-directing agent to synthesize iron vanadate (FeVO4) nanoparticles via co-precipitation method.
An organic additive to prepare crystalline nanorods of calcium tungstate (CaWO4) using calcium chloride and sodium tungstate via solvothermal process.
A surface modifier in the synthesis of calcium peroxide nanoparticles using CaCl2 as a precursor via hydrolysis-precipitation method.

A green solvent in combination with H2O in the preparation of Polyethylene glycol 200 by sulfanylation of 4-tosyloxycoumarins with thiourea and alkyl halides.
Polyethylene glycol 200 is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable.
Polyethylene glycol 200 is completely soluble in water and has an average molecular weight of 190 - 210.

Polyethylene glycol 200 are another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.
Polyethylene glycol 200 is a UV monomer with low volatility. It contains MEHQ (400 ppm) as inhibitor.
Polyethylene glycol 200 offers chemical resistance, good flexibility, impact strength and adhesive force.

Polyethylene glycol 200 is suitable for radiation-curable adhesives.
Polyethylene glycol 200 a thermoplastic polymer obtained by the polymerization of ethylene oxide; the various types of PEG vary according to their average molecular weight, from which they take their name.

Polyethylene glycol 200 is soluble in water and in most organic solvents, but with the increase of its molecular weight, solubility and hygroscopicity decrease.
The most recognized application of polyethylene glycols is the consolidation of waterlogged wood.

Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: <0.01 mm Hg ( 20 °C)
refractive index: n20/D 1.469
Flash point: 270 °C
storage temp.: 2-8°C
solubility H2O: 50 mg/mL, clear, colorless
form: waxy solid
color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Viscosity: 1,650-3,850cp (1% solution @ 25C)
Viscosity: 11cs (99C)
Viscosity: 4.5cs (99C)
Viscosity: 5,500-8,000cp (1% solution @ 25C)
Viscosity: 6cs (99C)
Viscosity: 7.4cs (99C)
Viscosity: 750cp (5% solution @ 25C)
Viscosity: 75cp (5% solution @ 25C)
Viscosity: 8,000cs (99C)
Viscosity: 8,800-17,600cp (5% solution @ 25C)
Viscosity: 93cs (99C)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃

Polyethylene Glycol 200 (PEG-200) is a polyether compound with the chemical structure H−(O−CH2−CH2)n−OH.
Traditionally, Polyethylene Glycol 200 is derived from petroleum-based sources.
Polyethylene Glycol 200 is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.

Polyethylene Glycol 200 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.
The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH.
Polyethylene Glycol 200 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.

Polyethylene Glycol 200 used in medicines for treating disimpaction and maintenance therapy for children with constipation.
Polyethylene Glycol 200 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Polyethylene Glycol 200 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.

X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
Polyethylene Glycol 200 is the basis of many skin creams (as cetomacrogol) and personal lubricants (frequently combined with glycerin).
Polyethylene Glycol 200 is used in a number of toothpastes[5] as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.

Polyethylene Glycol 200 is also under investigation for use in body armor, and in tattoos to monitor diabetes.
In low-molecular-weight formulations (e.g. PEG 200), Polyethylene Glycol 200 is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
Polyethylene Glycol 200 is also used as an anti-foaming agent in food and drinks.

The metabolism of Polyethylene glycol 200 involves the oxidation of the alcohol groups located on the PEG to a carboxylic acid.
For example, the diacid and hydroxyl acid metabolites of Polyethylene glycol 200 have been measured in the plasma and urine of burn patients and rabbits and in the bile of cats.
In the isolated guinea pig liver and in rat/guinea pig in vitro, Polyethylene glycol 200 has demonstrated to be sulfated.

Evidence from experiments with Polyethylene glycol 200 suggests that ethylene glycol is not formed as a metabolite of PEG in humans.
Negligible amounts of oxalic acid are liberated after the metabolism of PEG 12.
The first phase of metabolism of Polyethylene glycol 200 in mammals is regulated by the enzyme alcohol dehydrogenase.

Liver cytochorome Polyethylene glycol 200 enzymes may also play a role in the oxidation of PEG, although the evidence for this is not clear 12.
Also, Polyethylene glycol 200 has been shown to be metabolized by sulfotransferase enzymes.
Although there is evidence that Polyethylene glycol 200 can be metabolized to various phase 1 and phase 2 metabolites, the toxicology data presented above indicate that these metabolites are of very little toxicological concern.

However, metabolism of Polyethylene glycol 200 to the acid metabolite(s) has been implicated in the acidosis and hypercalcemia observed in patients after overdose 12.
Polyethylene glycol 200 is clear that these metabolites can be formed in multiple toxicology species and that the phase 1 metabolites are seen in animals and humans.
These data indicate that humans and animals will be exposed to similar metabolites after administration of PEG 12.

Metabolic clearance of Polyethylene glycol 200 decreases markedly as molecular weight increases.
Polyethylene glycol 200, up to 25% of the dose may be metabolized in humans (Schaffer et al., 1950); similar results are also seen in the rabbit 12.
Polyethylene glycol 200 by the oral route is molecular weight- dependent.

Polyethylene Glycol 200 is used as a binder in the preparation of technical ceramics.
Polyethylene Glycol 200 was used as an additive to silver halide photographic emulsions.
Polyethylene Glycol 200 is used to extend the size and durability of very large soap bubbles.

Polyethylene Glycol 200 is the main ingredient in many personal lubricants.
Polyethylene Glycol 200 is the main ingredient in the paint in paintballs
Polyethylene Glycol 200 has a wide range of potential uses.

Polyethylene Glycol 200 is a defoaming agent, lubricant and viscosity modifier in many different products.
Polyethylene Glycol 200 is also used as a coating for fresh fruit, as a solvent in metal working fluids, as a binder and modifier in latex paints, and as a humectant in inks and abrasives.
Specific industries that rely on Polyethylene Glycol 200 include cosmetics, health and medicine, textiles and more.

Uses:
In plastics manufacturing, Polyethylene glycol 200 is used as a lubricant in moulds to facilitate the removal of moulded parts and as a lubricant for external surfaces.
In the lubrication industry, Polyethylene glycol 200 is used as an additive in synthetic greases, cutting oils and hydraulic fluids, as a lubrication enhancer/enhancer/additive.
In rubber production as a mould lubricant to facilitate the removal of products from moulds in both synthetic and natural rubber production

In the textile industry, polyethylene glycol 200 as a fabric softener, a dye carrier, a dirt breaker (dispersant) and as an anti-static agent.
Polyethylene glycol 200 can also be used in carpet cleaning/refreshing agents.
In horticulture/ floriculture it is used as a humectant/active ingredient carrier.

When used in combination with water, Polyethylene glycol 200 prevents plants from drying out quickly, allowing cut flowers to last longer and growing plants to survive dry periods more easily.
In woodworking, Polyethylene glycol 200 is used as a preservative or stabilizer.
In the case of old wood, Polyethylene glycol 200 helps to preserve the original color and shape of the wood, especially when working with wood that has been under water or in wet environments.

In the case of green (fresh) wood, the polymer prevents the wood from drying out too quickly, thus preserving the original shape of the workpiece and avoiding the possibility of the wood becoming warped or cracked.
In the food industry, Polyethylene glycol 200 can be used as food additive E1521.
Polyethylene glycol 200 is commonly found as an additive in chewing gums, sweets and confectionery.

Polyethylene glycol 200 is found in small quantities as it is used as a carrier for pigments and as a component of moisturizers rather than as a main component.
Polyethylene glycol 200 is a condensation polymers of ethylene oxide and water with the general formula H(OCH2CH2)nOH, where n is the average number of repeating oxyethylene groups typically from 4 to about 180.
The low molecular weight members from n=2 to n=4 are diethylene glycol, triethylene glycol and tetraethylene glycol respectively, which are produced as pure compounds.

The low molecular weight compounds upto 700 are colorless, odorless viscous liquids with a freezing point from -10 C (diethylene gycol), while polymerized compounds with higher molecular weight than 1,000 are waxlike solids with melting point upto 67 C for n 180.
The abbreviation Polyethylene glycol 200 is termed in combination with a numeric suffix which indicates the average molecular weights.
One common feature of Polyethylene glycol 200 appears to be the water-soluble.

Polyethylene glycol 200 is soluble also in many organic solvents including aromatic hydrocarbons (not aliphatics).
They are used to make emulsifying agents and detergents, and as plasticizers, humectants, and water-soluble textile lubricants.
The wide range of chain lengths provide identical physical and chemical properties for the proper application selections directly or indirectly in the field of; Alkyd and polyester resin preparation to enhance water dispersability and water-based coatings.

Antidusting agent in agricultural formulations Brightening effect and adhesion enhance in electroplating and electroplating process.
Cleaners, detergents and soaps with low volatility and low toxicity solvent properties.
Coupling agent, humectant, solvent and lubricant in cosmetics and personal care bases.

Dimensional stabilizer in wood working operations Dye carrier in paints and inks Heat transfer fluid formulation and defoamer formulations.
Polyethylene glycol 200 low volatilie, water soluble, and noncorrosive lubricant without staining residue in food and package process.
Polyethylene glycol 200 mold release agent and lubricant in fabricating elastomers Paper coating for antisticking, color stabilizing, good gloss and free flow in calendering operations.

Plasticizer to increase lubricity and to impart a humectant property in ceramic mass, adhesives and binders.
Softener and antistatic agent for textiles Soldering fluxes with good spreading property.
Polyethylene glycol is non-toxic, odorless, neutral, lubricating, nonvolatile and nonirritating and is used in a variety of pharmaceuticals and in medications as a solven, dispensing agent, ointment and suppository bases, vehicle, and tablet excipient.

Polyethylene glycol 200 molecules of approximately 2000 monomers.
Polyethylene glycol 200 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown Polyethylene glycol 200 m aintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.

In rats, Polyethylene glycol 200 has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery.
This medication is used to relieve dry, irritated eyes.
Common causes for dry eyes include wind, sun, heating/air conditioning, computer use/reading, and certain medications.

Polyethylene glycol 200 may contain 1 or more of the following ingredients: carboxymethylcellulose, dextran, glycerin, hypromellose, Polyethylene glycol 200 (PEG 400), polysorbate, polyvinyl alcohol, povidone, or propylene glycol, among others.
Eye lubricants keep the eye moist, help to protect the eye from injury and infection, and decrease symptoms of dry eyes such as burning, itching, and feeling as if something is in the eye.
Polyethylene glycol 200 are widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations.

Polyethylene glycol 200 has been used experimentally in biodegradable polymeric matrices used in controlled-release systems.
Polyethylene glycol 200 are stable, hydrophilic substances that are essentially nonirritant to the skin;They do not readily penetrate the skin, although the polyethylene glycols are water-soluble and are easily removed from the skin by washing, making them useful as ointment bases.
Solid grades are generally employed in topical ointments, with the consistency of the base being adjusted by the addition of liquid grades of polyethylene glycol.

Mixtures of Polyethylene glycol 200s can be used as suppository bases,for which they have many advantages over fats.
For example, the melting point of the suppository can be made higher to withstand exposure to warmer climates; release of the drug is not dependent upon melting point; the physical stability on storage is better; and suppositories are readily miscible with rectal fluids.
Polyethylene glycol 200 have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the polyethylene glycol; and polyethylene glycols tend to be more irritating to mucous membranes than fats.

Polyethylene glycol 200 is industrially produced as a lubricating substance for various surfaces to reduce friction.
Polyethylene glycol 200 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
Polyethylene glycol 200 is a binder, coating agent, dispersing agent, flavoring adjuvant, and plasticizing agent that is a clear, colorless, viscous, hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration.

Polyethylene glycol 200 is soluble in water (mw 1,000) and many organic solvents.
Polyethylene glycol 200 is a binder, solvent, plasticizing agent, and softener widely used for cosmetic cream bases and pharmaceutical ointments.
Polyethylene glycol 200 are quite humectant up to a molecular weight of 500.

Beyond this weight, their water uptake diminishes.
Polyethylene glycol 200 is used in conjunction with carbon black to form a conductive composite.
Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.

Safety Profile:
Polyethylene glycol 200 administered topically may cause stinging, especially when applied to mucous membranes.
Hypersensitivity reactions to Polyethylene glycol 200 applied topically have also been reported, including urticaria and delayed allergic reactions.
The most serious adverse effects associated with Polyethylene glycol 200 are hyperosmolarity, metabolic acidosis, and renal failure following the topical use of polyethylene glycols in burn patients.

Topical preparations containing polyethylene glycols should therefore be used cautiously in patients with renal failure, extensive burns, or open wounds.
Oral administration of large quantities of Polyethylene glycol 200 can have a laxative effect.
Therapeutically, up to 4 L of an aqueous mixture of electrolytes and high-molecular-weight polyethylene glycol is consumed by patients undergoing bowel cleansing.

Liquid Polyethylene glycol 200 may be absorbed when taken orally, but the higher-molecular-weight polyethylene glycols are not significantly absorbed from the gastrointestinal tract.
Absorbed Polyethylene glycol 200 is excreted largely unchanged in the urine, although polyethylene glycols of low molecular weight may be partially metabolized.
The WHO has set an estimated acceptable daily intake of Polyethylene glycol 200 at up to 10 mg/kg body-weight.

In parenteral products, the maximum recommended concentration of Polyethylene glycol 200 is approximately 30% v/v as hemolytic effects have been observed at concentrations greater than about 40% v/v
When heated to decomposition Polyethylene glycol 200 emits acrid smoke and irritating fumes.
Polyethylene glycol 200s are widely used in a variety of pharmaceutical formulations.

Generally, they are regarded as nontoxic and nonirritant materials.
Adverse reactions to Polyethylene glycol 200 have been reported, the greatest toxicity being with glycols of low molecular weight.
However, the toxicity of glycols is relatively low.



POLYETHYLENE GLYCOL 2000
Polyethylene glycol 2000 is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.
Polyethylene glycol 2000 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.
The structure of Polyethylene glycol 2000 is commonly expressed as H−(O−CH2−CH2)n−OH.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

Uses
Medical uses
Pharmaceutical-grade Polyethylene glycol 2000 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
Polyethylene glycol 2000 is the basis of a number of laxatives.
Whole bowel irrigation with Polyethylene glycol 2000 and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation.
Macrogol (with brand names such as Laxido, Movicol and Miralax) is the generic name for Polyethylene glycol 2000 used as a laxative.
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000).
The possibility that Polyethylene glycol 2000 could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of Polyethylene glycol 2000 hydrogels (see Biological uses section) in a therapeutic has been theorized by Ma et al.
They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.
The gel with encapsulated stem cells was to be injected into the site of disease and crosslinked to create the microenvironment required for the stem cells to function.
Polyethylene glycol 2000 of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.

A Polyethylene glycol 2000 lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2.
Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids.
Proprietary lipid technology is used for each.
In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol.
Polyethylene glycol 2000 could trigger allergic reaction, and allergic reactions are the driver for both the United Kingdom and Canadian regulators to issue an advisory, noting that: two "individuals in the U.K. ... were treated and have recovered" from anaphylactic shock.
The US CDC stated that in their jurisdiction six cases of "severe allergic reaction" had been recorded from more than 250,000 vaccinations, and of those six only one person had a "history of vaccination reactions".

Health effects
Polyethylene glycol 2000 is considered biologically inert and safe by the U.S. FDA.
A 2015 study used a high-sensitivity ELISA assay to detect anti-Polyethylene glycol 2000 antibodies in 72% of plasma samples collected from 1990–1999, suggesting that anti-PEG antibodies may be present (typically at low levels) even amongst people never treated with PEGylated drugs.
Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG, hypersensitive reactions to Polyethylene glycol 2000 are an increasing concern.
Allergy to Polyethylene glycol 2000 is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain PEG or were manufactured with Polyethylene glycol 2000.

Production
The production of Polyethylene glycol 2000 was first reported in 1859.
Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.
Polyethylene glycol 2000 is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.
The reaction is catalyzed by acidic or basic catalysts.
Polyethylene glycol 2000 and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution).
Polymer chain length depends on the ratio of reactants.

HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H
Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic.
The anionic mechanism is preferable because it allows one to obtain Polyethylene glycol 2000 with a low polydispersity.
Polymerization of ethylene oxide is an exothermic process.
Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours.

Polyethylene oxide, or high-molecular-weight Polyethylene glycol 2000, is synthesized by suspension polymerization.
Polyethylene glycol 2000 is necessary to hold the growing polymer chain in solution in the course of the polycondensation process.
The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds.
To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used.
Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight Polyethylene glycol 2000.
POLYETHYLENE GLYCOL 300
Polyethylene glycol 300 is a clear, colorless, and odorless liquid that is used in a variety of applications due to its properties as a solvent, plasticizer, surfactant, and lubricant.
Polyethylene glycol 300 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons.
Polyethylene glycol 300 is not miscible with aliphatic hydrocarbons and diethyl ether.

CAS Number: 25322-68-3
EINECS Number: 500-038-2

Synonyms: Polyethylene Glycol 300, Macrogol 300, PEG 300, PEG-6, 5655G9Y8AQ, PEG-300, 220-045-1, CHEBI:49793, CARBOWAX PEG 300, JEECHEM 300, LIPO POLYGLYCOL 300, LIPOXOL 300 MED, LUMULSE PEG 300, NSC-201209, POLYETHYLENE GLYCOL 300 (II), POLYETHYLENE GLYCOL 300 (USP-RS), POLYGLYKOL 300, SABOPEG 300, TOHO PEG NO. 300, UPIWAX 300

Polyethylene glycol 300 is a polyether compound derived from petroleum with many applications, from industrial manufacturing to medicine.
Polyethylene glycol 300 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.
The structure of PEG is commonly expressed as H−(O−CH2−CH2)n−OH.

Polyethylene Glycol 300 commonly referred to as PEG 300, is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient.
Due to its low toxicity it can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.
Polyethylene glycol 300 is a type of polyethylene glycol, which is a polymer made from ethylene oxide and water.

Therefore, reaction products can be extracted from the reaction media with those solvents.
Polyethylene glycol 300 is a polymer which is hydrolyzed by ethylene oxide.
Polyethylene glycol 300 has no toxicity and irritation.

Polyethylene glycol 300 is widely used in various pharmaceutical preparations.
The toxicity of low molecular weight Polyethylene glycol 300 is relatively large.
In general, the toxicity of diols is very low.

Topical application of Polyethylene glycol 300, especially mucosal drug, can cause irritant pain.
In topical lotion, Polyethylene glycol 300 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
Diarrhoea can occur in large doses of oral administration.

In injection, the maximum polyethylene glycol 300 concentration is about 30% (V/V).
Polyethylene glycol 300 is a non-ionic hydrophilic polymer and is available in different molecular weights.
Polyethylene glycol 300 either exists in the form of a linear or branched structure.

Polyethylene glycol 300 aids in the purification and crystal growth of proteins and nucleic acids.
Polyethylene glycol 300 is a clear, colorless, viscous liquid.
Due in part to its low toxicity, PEG 300 is widely used in a variety of pharmaceutical formulations.

Polyethylene glycol 300 is strongly hydrophilic.
The partition coefficient of Polyethylene glycol 300 between hexane and water is 0.000015 (log𝑃=−4.8{\displaystyle P=-4.8}), indicating that when Polyethylene glycol 300 is mixed with water and hexane, there are only 15 parts of Polyethylene glycol 300 in the hexane layer per 1 million parts of PEG 400 in the water layer.
Polyethylene glycol 300 is a low-molecular-weight grade of polyethylene glycol.

A study developed an in vitro testing model for ventricular shunt materials, highlighting the utility of Polyethylene Glycol (PEG) as an antifouling coating, potentially improving shunt performance in clinical settings.
Antibacterial and anti-inflammatory properties in hydrogels: Research on Polyethylene glycol 300 hydrogels incorporated with Imidazolium Poly(ionic liquids) microspheres demonstrated enhanced antibacterial and anti-inflammatory properties, suggesting applications in medical coatings and drug delivery systems.

A study described the development of a Gellan Gum, Polyethylene glycol 300, and Hydroxyapatite composite scaffold, enhanced with Ginseng derived Compound K, which offers potential applications in bone regeneration and tissue engineering.
A comprehensive review discussed the advances and challenges in achieving uniform Polyethylene glycol 300, which is critical for its consistency in various industrial and pharmaceutical applications.
AI-Driven optimization of electrospun scaffolds: A study utilized artificial intelligence to optimize PCL/PEG electrospun scaffolds, significantly enhancing in vivo wound healing capabilities, highlighting its potential for medical textiles and tissue engineering applications.

Polyethylene glycol 300 is one of the most commonly used chemical polyethers in manufacturing, medicine and many other applications.
Polyethylene glycol 300 is available in multiple forms for various uses. The most common way of differentiating between PEGs is by molecular weight.
For example, Polyethylene glycol 300 refers to a polyethylene glycol product with an average weight of 300 daltons.

Acme-Hardesty produces a bio-based Polyethylene glycol 300 product for a wide range of manufacturing processes.
Polyethylene glycol 300 is not derived from raw petroleum materials, making it a more sustainable choice for any environmentally conscious manufacturer.
Keep reading to learn more about potential applications for our PEG 300 product.

Polyethylene glycol 300 and related polymers (PEG phospholipid constructs) are often sonicated when used in biomedical applications.
However, as reported by Murali et al., Polyethylene glycol 300 is very sensitive to sonolytic degradation and PEG degradation products can be toxic to mammalian cells.
Polyethylene glycol 300 is, thus, imperative to assess potential PEG degradation to ensure that the final material does not contain undocumented contaminants that can introduce artifacts into experimental results.

Polyethylene glycol 300 and methoxypolyethylene glycols are manufactured by Dow Chemical under the trade name Carbowax for industrial use, and Carbowax Sentry for food and pharmaceutical use.
They vary in consistency from liquid to solid, depending on the molecular weight, as indicated by a number following the name.
They are used commercially in numerous applications, including foods, in cosmetics, in pharmaceutics, in biomedicine, as dispersing agents, as solvents, in ointments, in suppository bases, as tablet excipients, and as laxatives.

Some specific groups are lauromacrogols, nonoxynols, octoxynols, and poloxamers.
Polyethylene glycol 300 along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials.
Polyethylene glycol 300 permits cell fusion through its interaction with the cell membrane.

Polyethylene glycol 300 has been used in the production of monoclonal antibodies.
Polyethylene glycol 300, NF acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.

All SpectrumPolyethylene glycol 300 grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP).
The low-molecular weight liquid Polyethylene glycol 300 is an excellent solvent for a large number of substances that do not readily dissolve in water.

Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: refractive index: n20/D 1.469
Flash point: 270 °C
storage temp.: 2-8°C
solubility H2O: 50 mg/mL, clear, colorless
form: waxy solid
color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Viscosity: 1,650-3,850cp (1% solution @ 25C)
Viscosity: 11cs (99C)
Viscosity: 4.5cs (99C)
Viscosity: 5,500-8,000cp (1% solution @ 25C)
Viscosity: 6cs (99C)
Viscosity: 7.4cs (99C)
Viscosity: 750cp (5% solution @ 25C)
Viscosity: 75cp (5% solution @ 25C)
Viscosity: 8,000cs (99C)
Viscosity: 8,800-17,600cp (5% solution @ 25C)
Viscosity: 93cs (99C)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃

They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations.
Liver cytochorome Polyethylene glycol 300 enzymes may also play a role in the oxidation of PEG, although the evidence for this is not clear 12.
Also, Polyethylene glycol 300 has been shown to be metabolized by sulfotransferase enzymes.

Although there is evidence that Polyethylene glycol 300 can be metabolized to various phase 1 and phase 2 metabolites, the toxicology data presented above indicate that these metabolites are of very little toxicological concern.
However, metabolism of Polyethylene glycol 300 to the acid metabolite(s) has been implicated in the acidosis and hypercalcemia observed in patients after overdose 12.
Polyethylene glycol 300 is clear that these metabolites can be formed in multiple toxicology species and that the phase 1 metabolites are seen in animals and humans.

These data indicate that humans and animals will be exposed to similar metabolites after administration of PEG 12.
Metabolic clearance of Polyethylene glycol 300 decreases markedly as molecular weight increases.
Polyethylene glycol 300, up to 25% of the dose may be metabolized in humans (Schaffer et al., 1950); similar results are also seen in the rabbit 12.

Polyethylene glycol 300 by the oral route is molecular weight- dependent.
Urinary recovery data for PEG400 indicate that 50 to 60% of Polyethylene glycol 300 with this molecular weight is absorbed from the intestine 12.
In the case of Polyethylene glycol 300, up to 25% of the dose may be metabolized in humans.

Polyethylene glycol 300 is also known as polyoxirane (PEO).
Polyethylene glycol 300 is a linear polyether obtained by ring opening polymerization of ethylene oxide.
The viscosity of polyethylene glycol solution is sensitive to the shear rate and it is not easy for bacteria to grow on polyethylene glycol.

The condensation polymer of ethylene oxide and water.
Polyethylene glycol 300 is a cream matrix for preparing water-soluble drugs.
Polyethylene glycol 300 can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.

Drug sustained-release and immobilized enzyme carrier.
The polyethylene glycol solution is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
Surface modification of medical polymer materials.

The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing Polyethylene glycol 300 on the surface of medical polymers.
Polyethylene glycol 300 can make the membrane of the alkanol contraceptive pill.
Polyethylene glycol 300 can make hydrophilic anticoagulant polyurethane.

Polyethylene glycol 300 is an osmotic laxative.
Polyethylene glycol 300 can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
Polyethylene glycol 300 nontoxic and gelatinous nature can be used as a component of denture fixer.

Polyethylene glycol 300 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation.
Polyethylene glycol 300 absorbs water from the solution, so it is also used to concentrate the solution.
Polyethylene glycol 300 is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable.

Polyethylene glycol 300 is completely soluble in water and has an average molecular weight of 380 - 420.
Polyethylene glycol 300 is another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.
Polyethylene glycol 300 is a high quality research product used as multipurpose polymer of ethelyne glycol for various biochemical, molecular biology and molecular diagnostic applications.

Polyethylene glycol 300 is a polyether compound with many applications from industrial manufacturing to medicine.
Applications of Polyethylene glycol 300 include uses in cosmetics, personal care products in which it is used as a solvent and humectant.
Polyethylene glycol 300 is used in a wide range of lubricant applications due to their low volatility, solubility in water, and natural lubricity

The ring-opening polymerization of ethylene oxide is readily effected by a variety of ionic reagents and several types of polymer have been prepared.
For commercial purposes, poly(ethylene oxide)s of low molecular weight and of very high molecular weight are of interest.
Polyethylene glycol 300s of low molecular weight, i.e. below about 3000, are generally prepared by passing ethylene oxide into Polyethylene glycol 300 and about 0.3 MPa (3 atmospheres) pressure, using an alkaline initiator such as sodium hydroxide.

The polymers produced by these methods are thus terminated mainly by hydroxy groups (a few unsaturated end-groups are also formed) and are often referred to as poly(ethylene glycol)s.
Polyethylene glycol 300s with molecular weights in the range 200-600 are viscous liquids which find use as surfactants in inks and paints and as humectants.
At molecular weights above about 600, poly(ethylene glycol)s are low-melting waxy solids, uses of which include pharmaceutical and cosmetic bases, lubricants and mould release agents.

Polyethylene glycol 300 may be noted that homogeneous cationic polymerization of ethylene oxide also generally leads to low molecular weight products; typical initiators include aluminium chloride, boron trifluoride and titanium tetrachloride.
Systems of this type are not utilized on a commercial scale.
Polyethylene glycol 300s of molecular weight ranging from about 100000 to 5 x 106 and above are available.

Details of the techniques used to manufacture these polymers have not been disclosed, but the essential feature is the use of (generally) heterogeneous initiator systems.
Effective initiators are mainly of two types, namely alkaline earth compounds (e.g. carbonates and oxides of calcium, barium and strontium) and organometallic compounds (e.g. aluminium and zinc alkyls and alkoxides, commonly with added coinitiators).
The precise modes of action of these initiators have not, as yet, been fully resolved.

However, Polyethylene glycol 300 is now generally thought that polymerization occurs through a co-ordinated anionic mechanism, in which the ethylene oxide is coordinated to the initiator through an unshared electron pair on the oxirane oxygen atom.
Unlike the low molecular weight poly(ethylene oxide)s, the high molecular weight polymers are tough and extensible.
They are highly crystalline, with a melting point of 66??C.

Unlike most water-soluble polymers, the high molecular weight poly(ethylene oxide)s may be melt processed; they may be injection moulded, extruded and calendered without difficulty.
Polyethylene glycol 300s are soluble in an unusually broad range of solvents, which includes water; chlorinated hydrocarbons such as carbon tetrachloride and methylene dichloride; aromatic hydrocarbons such as benzene and toluene; ketones such as acetone and methyl ethyl ketone; and alcohols such as methanol and isopropanol.

There is an upper temperature limit of solubility in water for the high molecular weight poly(ethylene oxide)s; this varies with concentration and molecular weight but is usually between 90 and 100??C.
Water-solubility is due to the ability of the polyether to form hydrogen bonds with water; these bonds are broken when the temperature is raised, restoring the anhydrous polymer which is precipated from the solution.
High molecular weight poly(ethylene oxide)s find use as water-soluble packaging films and capsules for such products as laundry powders, colour concentrates, tablets and seeds.

In solution, the polymers are used as thickeners in pharmaceutical and cosmetic preparations, textile sizes and latex stabilizers.
Dissolves many drugs and active ingredients to form clear, stable solutions.
Polyethylene glycol 300 is used in drug formulations to ensure the stability and bioavailability of the active ingredients.

Polyethylene glycol 300 is used in over-the-counter laxative products like MiraLAX, aiding in bowel movements by retaining water in the stool.
Provides a smooth and soft texture to creams and lotions, enhancing their spreadability.
Helps bind together ingredients in solid products like pressed powders and tablets.

Helps active ingredients penetrate the skin more effectively.
Reduces friction between moving parts in machinery and industrial processes.
Polyethylene glycol 300 improves the flexibility and durability of plastics and resins.

Polyethylene glycol 300 reduces static electricity buildup in manufacturing processes involving plastics and textiles.
Polyethylene glycol 300 is used in products like candy and confectionery to maintain moisture and improve texture.
Helps evenly distribute flavors, colors, and other additives in food products.

Facilitates the smooth operation of surgical instruments and reduces wear and tear.
Polyethylene glycol 300 is used to coat medical devices to reduce friction and improve biocompatibility.
Polyethylene glycol 300 is generally recognized as safe by regulatory agencies such as the FDA.

Non-toxic when used in appropriate amounts, but excessive ingestion can lead to gastrointestinal disturbances.
Biodegradable, but high concentrations in water bodies can affect aquatic life.
Polyethylene glycol 300 is used as a carrier for pesticides and herbicides to improve their effectiveness.

Acts as a dispersing agent and helps improve the flow and leveling properties of paints.
Enhances the performance of adhesives by improving flexibility and reducing brittleness.
Should be stored in a cool, dry place away from direct sunlight and moisture.

Generally safe to handle, but standard precautions such as wearing gloves and safety goggles are recommended.
Polyethylene glycol 300 was obtained by polymerization of ethylene oxide in an autoclave at 80-100°C using as a catalyst dipotassium alcogolate of Polyethylene glycol 300.
Dipotassium alcogolate of Polyethylene glycol 300 was synthesized by a heating of the dry mixture of Polyethylene glycol 300 and potassium hydroxide.

The molecular weight of polymer was regulated by the ratio of monomer:catalyst.
Polyethylene glycol 300 is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power.
However, equilibrium constants for complex formation vary considerably from one substance to another, and certain drugs such as Penicillin G and Bacitracin can even become inactivated.

The effect of the Polyethylene glycol 300 on the efficacy and absorbtion of a drug must therefore always be determined in tests.
With regard to incompatible substances, please see the remarks in the European Pharmacopoeia, Vol. II/3, Monographs M1, Macrogol 300, p. 3.
Polyethylene glycol 300s can also be used to adjust the viscosity of liquid pharmaceutical preparations and ointments, to modify their absorption properties and to stabilise the preparation.

Polyethylene glycol 300 are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions.
Because many Polyethylene glycol 300 types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations.
Polyethylene glycol 300, along with their many nonionic derivatives, are widely utilized in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.

Polyethylene glycol 300 is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.
Polyethylene glycol 300 is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Polyethylene glycol 300 is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye 7.

Polyethylene oxide, or high-molecular-weight polyethylene glycol, is synthesized by suspension polymerization.
Polyethylene glycol 300 is necessary to hold the growing polymer chain in solution in the course of the polycondensation process.
The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds.

To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used.
Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight polyethylene glycol.
Polyethylene glycol 300 is a water-miscible polyether with an average molecular weight of 300 g/mol.

Polyethylene glycol 300 is a clear viscous liquid at room temperature with non-volatile, stable properties.
Polyethylene glycol 300 are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries.
They serve as solubilizers, excipients, lubricants, and chemical reagents.

Low molecular weight glycols are observed to exhibit antibacterial properties as well.
Polyethylene glycol 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.
Polyethylene glycol 300 are made of condensed ethylene oxide and water.

They are widely used in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.
Polyethylene glycol 300 is a colourless liquid that acts as a lubricant, coating curfaces in both aqueous and non-aqueous environments.
Low molecular weight glycols are also observed to exhibit antibacterial properties.

Polyethylene glycol 300 is commonly found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
These Secondary Standards are qualified as Certified Reference Materials.

These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Polyethylene glycol 300 is one of the most commonly used chemical polyethers in manufacturing, medicine and many other applications.
Polyethylene glycol 300 is available in multiple forms for various uses.

The most common way of differentiating between Polyethylene glycol 300 is by molecular weight.
Polyethylene glycol 300 is used as a base for skin creams and other personal care products, as well as a solvent and viscosity modifier in soaps and detergents.
Polyethylene glycol 300 is also used to process rubber, plastics and textiles, as an additive in lubricants and grease, and as a humectant, dye carrier and binder in paints and inks.

Polyethylene glycol 300 is colorless, almost odorless and tasteless liquid at room temperature.
Polyethylene glycol 300 is manufactured by alkali-catalysed polymerization of ethylene oxide with subsequent neutralization of the catalyst.
Polyethylene glycol 300 is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointment and suppository base, and tablet and capsule lubricant.

Polyethylene glycol 300 has low toxicity with systemic absorption less than 0.5%.
Polyethylene glycol 300 indicates the average molecular weight of the specific PEG at 400.PEG 3350 is a laxative.
Polyethylene glycol 300 is a liquid PEG excipient grade product, produced under IPEC GMP conditions.

Polyethylene glycol 300 is a polyether compound with many applications from industrial manufacturing to medicine.
Polyethylene glycol 300 commonly referred to as PEG 300, is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as an excipient and active ingredient.
Due to its low toxicity, Polyethylene glycol 300 can be used as a lubricating coating for various surfaces in aqueous and non-aqueous environments, a reagent in biochemistry to create very high osmotic pressures, a polar stationary phase for gas chromatography and as a binder.

Polyethylene glycol 300 is a water-miscible polyether widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries.
Polyethylene glycol 300 serves as a kind of solubilizer, excipient, lubricant, and chemical reagent.
Polyethylene glycol 300 is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable.

Polyethylene glycol 300 is completely soluble in water and has an average molecular weight of 288 - 311.
Polyethylene glycol 300 is another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.
Polyethylene glycol 300 is PEG-6-based plasticizer and mold release agent.

Polyethylene glycol 300 possesses lubricity and humectant properties.
Polyethylene glycol 300 maintains wet-tack strength.
Polyethylene glycol 300 is used in pressure sensitive and thermoplastic adhesives.

Polyethylene glycol 300 is a water-miscible polyether with an average molecular weight of 300 g/mol.
Polyethylene glycol 300 is a clear viscous liquid at room temperature with non-volatile, stable properties.
Polyethylene glycol 300 is widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries.

They serve as solubilizers, excipients, lubricants, and chemical reagents.
Low molecular weight glycols are observed to exhibit antibacterial properties as well.
Polyethylene glycol 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes.

Polyethylene glycol 300 is a neutral and biocompatible hydrophilic polymer.
Polyethylene glycol 300 is usually used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene glycol 300 is used as a moisturizer, solubiliser in antiperspirant and deodorants, shampoos and liquid soap, hair styling products, bar soaps and oral care products as a stabilizer and wetting agent for drilling.

Polyethylene glycol 300 is a polymer which is hydrolyzed by ethylene oxide.
Polyethylene glycol 300 has no toxicity and irritation.
Polyethylene glycol 300 is widely used in various pharmaceutical preparations.

The toxicity of low molecular weight polyethylene glycol is relatively large.
In general, the toxicity of diols is very low.
Topical application of Polyethylene glycol 300, especially mucosal drug, can cause irritant pain.

In topical lotion, Polyethylene glycol 300 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
Polyethylene glycol 300 is a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene.
The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups.

The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups.
The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides.
The average molecular weight of any specific polyethylene glycol product falls within quite narrow limits (°5%).

The number of ethylene oxide units or their approximate molecular weight commonly designates the nomenclature of specific polyethylene glycols.
Polyethylene glycol 300 with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid.
These materials are nonvolatile, water-soluble, tasteless, and odorless.

They are miscible with water, alcohols, esters, ketones, aromatic solvents, and chlorinated hydrocarbons, but immiscible with alkanes, paraffins, waxes, and ethers.
Polyethylene glycol 300 is a binder, coating agent, dispersing agent, flavoring adjuvant, and plasticizing agent that is a clear, colorless, viscous, hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration.

Polyethylene glycol 300 is soluble in water (mw 1,000) and many organic solvents.
Polyethylene glycol 300 molecules of approximately 2000 monomers.

Polyethylene glycol 300 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown Polyethylene glycol 300 maintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.

Uses:
Polyethylene glycol 300 is used as an additive in lubricants and adhesives, as well as as a dye carrier and binder in paints and inks.
Polyethylene glycol 300 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
Polyethylene glycol 300 is the basis of a number of laxatives (as MiraLax, RestoraLAX, etc.).

Whole bowel irrigation with Polyethylene glycol 300 and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation.
Macrogol (with brand names such as Laxido, Movicol and Miralax) is the generic name for polyethylene glycol used as a laxative.
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000).

The possibility that Polyethylene glycol 300 could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.
An example of Polyethylene glycol 300 hydrogels (see Biological uses section) in a therapeutic has been theorized by Ma et al.
They propose using the hydrogel to address periodontitis (gum disease) by encapsulating stem cells in the gel that promote healing in the gums.

The gel with encapsulated stem cells was to be injected into the site of disease and crosslinked to create the microenvironment required for the stem cells to function.
Polyethylene glycol 300 of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity.
A Polyethylene glycol 300 lipid is used as an excipient in both the Moderna and Pfizer–BioNTech vaccines for SARS-CoV-2.

Both RNA vaccines consist of messenger RNA, or mRNA, encased in a bubble of oily molecules called lipids.
Proprietary lipid technology is used for each. In both vaccines, the bubbles are coated with a stabilizing molecule of polyethylene glycol.
Polyethylene glycol 300 could trigger allergic reaction, and allergic reactions are the driver for both the United Kingdom and Canadian regulators to issue an advisory, noting that: two "individuals in the U.K.

Polyethylene glycol 300 is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Polyethylene glycol 300 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.
Polyethylene glycol 300 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.

In addition, Polyethylene glycol 300 is used when working with green wood as a stabilizer, and to prevent shrinkage.
Polyethylene glycol 300 has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.
These painted artifacts were created during the Qin Shi Huang (first emperor of China) era.

Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air.
The paint would subsequently flake off in about four minutes.
The German Bavarian State Conservation Office developed a Polyethylene glycol 300 preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.

Polyethylene glycol 300 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
Polyethylene glycol 300 derivatives, such as narrow range ethoxylates, are used as surfactants.
Polyethylene glycol 300 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.

Polyethylene glycol 300 is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.
Polyethylene glycol 300 has been used as a solvent for aryl thioether synthesis.
An example study was done using PEG-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.

This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
Polyethylene glycol 300 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Although Polyethylene glycol 300 is considered biologically inert, it can form non-covalent complexes with monovalent cations such as Na+, K+, Rb+, and Cs+, affecting equilibrium constants of biochemical reactions.

Polyethylene glycol 300 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
Polyethylene glycol 300 is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.

In microbiology, Polyethylene glycol 300 precipitation is used to concentrate viruses.
Polyethylene glycol 300 is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be Polyethylene glycol 300-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.

The size of the Polyethylene glycol 300 polymer has been shown to be important, with larger polymers achieving the best immune protection.
Polyethylene glycol 300 is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.
In blood banking, Polyethylene glycol 300 is used as a potentiator to enhance detection of antigens and antibodies.

When working with phenol in a laboratory situation, Polyethylene glycol 300 can be used on phenol skin burns to deactivate any residual phenol.
In biophysics, Polyethylene glycol 300s are the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.
Polyethylene glycol 300 is a condensation polymers of ethylene oxide and water with the general formula H(OCH2CH2)nOH, where n is the average number of repeating oxyethylene groups typically from 4 to about 180.

The low molecular weight members from n=2 to n=4 are diethylene glycol, triethylene glycol and tetraethylene glycol respectively, which are produced as pure compounds.
The low molecular weight compounds upto 700 are colorless, odorless viscous liquids with a freezing point from -10 C (diethylene gycol), while polymerized compounds with higher molecular weight than 1,000 are waxlike solids with melting point upto 67 C for n 180.

The abbreviation Polyethylene glycol 300 is termed in combination with a numeric suffix which indicates the average molecular weights.
One common feature of Polyethylene glycol 300 appears to be the water-soluble.
Polyethylene glycol 300 is soluble also in many organic solvents including aromatic hydrocarbons (not aliphatics).

They are used to make emulsifying agents and detergents, and as plasticizers, humectants, and water-soluble textile lubricants.
The wide range of chain lengths provide identical physical and chemical properties for the proper application selections directly or indirectly in the field of; Alkyd and polyester resin preparation to enhance water dispersability and water-based coatings.
Antidusting agent in agricultural formulations Brightening effect and adhesion enhance in electroplating and electroplating process.

Cleaners, detergents and soaps with low volatility and low toxicity solvent properties.
Coupling agent, humectant, solvent and lubricant in cosmetics and personal care bases.
Dimensional stabilizer in wood working operations Dye carrier in paints and inks Heat transfer fluid formulation and defoamer formulations.

Polyethylene glycol 300 low volatilie, water soluble, and noncorrosive lubricant without staining residue in food and package process.
Polyethylene glycol 300 mold release agent and lubricant in fabricating elastomers Paper coating for antisticking, color stabilizing, good gloss and free flow in calendering operations.
Plasticizer to increase lubricity and to impart a humectant property in ceramic mass, adhesives and binders.

Softener and antistatic agent for textiles Soldering fluxes with good spreading property.
Polyethylene glycol is non-toxic, odorless, neutral, lubricating, nonvolatile and nonirritating and is used in a variety of pharmaceuticals and in medications as a solven, dispensing agent, ointment and suppository bases, vehicle, and tablet excipient.
Polyethylene glycol 300 molecules of approximately 2000 monomers.

Polyethylene glycol 300 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown Polyethylene glycol 300 m aintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.
In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery.

Polyethylene glycol 300 is used in a number of toothpastes as a dispersant. In this application, it binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Polyethylene glycol 300 is under investigation for use in liquid body armor, and in tattoos to monitor diabetes.
Polymer segments derived from PEG polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions.

In low-molecular-weight formulations (e.g. PEG 400), it is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
Polyethylene glycol 300 is used as an anti-foaming agent in food and drinks – its INS number is 1521[33] or E1521 in the EU.
A nitrate ester-plasticized Polyethylene glycol 300 is used in Trident II submarine-launched ballistic missile solid rocket fuel.

Dimethyl ethers of Polyethylene glycol 300 are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.
Polyethylene glycol 300 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
Polyethylene glycol 300 is used as a polymer host for solid polymer electrolytes.

Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving Polyethylene glycol 300, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
Polyethylene glycol 300 is injected into industrial processes to reduce foaming in separation equipment.
Polyethylene glycol 300 is used as a binder in the preparation of technical ceramics.

Polyethylene glycol 300 was used as an additive to silver halide photographic emulsions.
Polyethylene glycol 300 is used to extend the size and durability of very large soap bubbles.
Polyethylene glycol 300 is the main ingredient in many personal lubricants.[citation needed] (Not to be confused with propylene glycol.)

Polyethylene glycol 300 is the main ingredient in the paint (known as "fill") in paintballs.
A 2015 study used a high-sensitivity ELISA assay to detect anti-PEG antibodies in 72% of plasma samples collected from 1990–1999, suggesting that anti-Polyethylene glycol 300 antibodies may be present (typically at low levels) even amongst people never treated with PEGylated drugs.

Due to its ubiquity in a multitude of products and the large percentage of the population with antibodies to PEG, hypersensitive reactions to PEG are an increasing concern.
Allergy to PEG is usually discovered after a person has been diagnosed with an allergy to an increasing number of seemingly unrelated products, including processed foods, cosmetics, drugs, and other substances that contain Polyethylene glycol 300 or were manufactured with PEG.

Safety Profile:
Polyethylene glycol 300's have "very low singledose oral toxicity", on the order of tens of grams per kg body weight (oral).
Because of its low toxicity, Polyethylene glycol 300 is used in a variety of edible products.
The polymer is used as a lubricating coating for various surfaces in aqueous and non-aqueous environments.

The precursor to PEGs is ethylene oxide, which is hazardous.
Polyethylene glycol 300 and its ethers are nephrotoxic if applied to damaged skin.

POLYETHYLENE GLYCOL 300
PEG 300 Applications PEG 300 Application Polyethylene glycol 1500 for synthesis. CAS 25322-68-3, pH 4 - 7 (100 g/l, H₂O, 20 °C). PEG 300 Physicochemical Information PEG 300 Boiling point >200 °C (1013 hPa) PEG 300 Density 1.2 g/cm3 (20 °C) PEG 300 Flash point 240 °C PEG 300 Ignition temperature 420 °C PEG 300 Melting Point 43 - 49 °C PEG 300 pH value 4 - 7 (100 g/l, H₂O, 20 °C) PEG 300 Vapor pressure <0.01 hPa (20 °C) PEG 300 Bulk density 400 - 500 kg/m3 PEG 300 Solubility 650 g/l PEG 300 Toxicological Information PEG 300 LD 50 oral LD50 Rat 28000 mg/kg PEG 300 LD 50 dermal LD50 Rabbit > 20000 mg/kg PEG 300 Safety Information according to GHS PEG 300 Storage class 10 Combustible liquids PEG 300 WGK WGK 1 slightly hazardous to water PEG 300 Disposal 3 PEG 300 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. PEG 300 Storage and Shipping Information PEG 300 Storage Store below +30°C. PEG 300 Transport Information PEG 300 Declaration (railroad and road) ADR, RID Kein Gefahrgut PEG 300 Declaration (transport by air) IATA-DGR No Dangerous Good PEG 300 Declaration (transport by sea) IMDG-Code No Dangerous Good PEG 300 Specifications PEG 300 Melting range (lower value) ≥ 43 °C PEG 300 Melting range (upper value) ≤ 49 °C PEG 300 Hydroxyl value 70 - 80 PEG 300 Average molecular mass 1400 - 1600 PEG 300 Identity (IR) passes test Activated PEG 300s (for conjugation to biologics) PEG 300-PLA or PEG 300-PLGA (for nanoparticle formulations of drugs) Linear and branched functionalized polyethylene imines and other polyimines (for oligo-nucleotide binding and delivery) PEG 300-pAsp / PEG 300-pGlu (for oligo-nucleotide binding and delivery) Hyperbranched polyglycerols (for drug delivery and protein formulation) Other polymers for nanoparticle formation (drug delivery) Poly(ethylene glycol) (PEG 300) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG 300 and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG 300 also interacts with cell membrane, thereby allowing cell fusion.Polyethylene Glycol 1500 (PEG 300-1500) has been used to mediate cell fusion.PEG 300 is a polymer of ethylene oxide with an average molecular weight of 1500. This polymeric material is an excellent solubiliser and can be used in a wide variety of home care and I&I applications.Polyethylene glycol. PEG- 1500 by Dynamic International is a surfactant. It is available in the form of milky white solid. PEG- 1500 is used in cream and shampoo base material.Crystallization grade Polyethylene glycol 1500(PEG 300) for formulating screens or for optimization.PEG 300 Eye contact Unlikely to cause eye irritation in man.PEG 300 Skin contact Unlikely to cause skin irritation in man.PEG 300 Inhalation This material may cause irritation following inhalation.PEG 300 Ingestion Will cause irritation of the gastrointestinal tract.Low oral toxicity, but ingestion may cause irritation of the gastrointestinal tract.PEG 300 Eye contact Irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.PEG 300 Skin contact Remove contaminated clothing. Wash skin with soap and water. If symptoms develop, obtain medical attention.PEG 300 Inhalation Remove patient from exposure. Obtain medical attention if ill effects occur.PEG 300 Ingestion Do not induce vomiting. Wash out mouth with water and give 200-300 ml (half a pint) of water to drink. Obtain medical attention if ill effects occur.PEG 300 Further Medical Treatment Symptomatic treatment and supportive therapy as indicated.PEG 300 Extinguishing Media Water fog, alcohol foam, carbon dioxide, dry chemical.PEG 300 Unsuitable Extinguishing Media None known.PEG 300 Special fire-fighting protective equipment A self contained breathing apparatus and suitable protective clothing must be worn in fire conditions.PEG 300 Fire and explosion hazards Combustible but not readily ignited. PEG 300 Colour white PEG 300 Form solid PEG 300 Odour mild PEG 300 pH approx 5 - 7 5% In water PEG 300 Boiling point/boiling range (°C) No data. PEG 300 Flash Point (ºC) > 260 (open cup) PEG 300 Autoignition Temperature (ºC) approx 420 PEG 300 Flammable Limits No data. PEG 300 Explosive Properties No data. PEG 300 Oxidising Properties No data. PEG 300 Vapour Density No data. PEG 300 Solubility in water soluble PEG 300 Solubility in other ingredients Soluble in many organic solvents, insoluble in:, aliphatic hydrocarbons PEG 300 Partition Coefficient No data. PEG 300 Dynamic viscosity (mPa.s) approx 30 @99°C PEG 300 Density (g/ml) 1.208 @ 20 °C PEG 300 Stability Stable under normal conditions. PEG 300 Materials to avoid Strong oxidising agents. PEG 300 Conditions to avoid None known PEG 300 Hazardous decomposition products None known PEG 300 Hazardous polymerisation Will not occur
POLYETHYLENE GLYCOL 3000
Polyethylene glycol 3000 is a polymer which is hydrolyzed by ethylene oxide.
Polyethylene glycol 3000 has no toxicity and irritation.
Polyethylene glycol 3000 is widely used in various pharmaceutical preparations.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

Polyethylene glycol 3000, referred to as PEG 3000, is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments, and suppository base, and tablet and capsule lubricant.
Polyethylene glycol 3000 has low toxicity with systemic absorption less than 0.5%.
PEGylation occurs when PEGs are attached to various protein medications, allowing for greater solubility for certain drugs.
Examples of PEGylated medications include PEG-interferon alpha (Pegintron) and PEG-filgrastim (Neulasta).
PEG is also available as a bowel prep for colonoscopy procedures and as a laxative.
Polyethylene glycol 3000 indicates the average molecular weight of the specific PEG at 3000.
Polyethylene glycol 3000 is a laxative available over-the-counter by the name of Miralax.
In this case, Polyethylene glycol 3000 is considered an "active" ingredient, even though systemic absorption is less than 0.5%.

Polyethylene glycol 3000 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: Polyethylene glycol 3000 (25322-68-3)
EPA Substance Registry System: Polyethylene glycol 3000 (25322-68-3)

Polyethylene glycol 3000 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
Polyethylene glycol 3000 is a binder, coating agent, dispersing agent, flavoring adjuvant, and plasticizing agent that is a clear, colorless, viscous, hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration.
it is soluble in water (mw 1,000) and many organic solvents.
Polyethylene glycol 3000 is a binder, solvent, plasticizing agent, and softener widely used for cosmetic cream bases and pharmaceutical ointments.
Pegs are quite humectant up to a molecular weight of 500.
Beyond this weight, their water uptake diminishes.
Used in conjunction with carbon black to form a conductive composite.
Polymer nanospheres of Polyethylene glycol 3000 were used for drug delivery.

Applications: Polyethylene glycol 3000 has various applications in different industries, including:
1. Pharmaceuticals: PEG 3000 is a common ingredient in many pharmaceutical formulations.
Polyethylene glycol 3000 is used as a base for gels, emulsions, creams, and ointments.
Polyethylene glycol 3000 also serves as a solubilizer for poorly soluble drugs.
2. Cosmetics: PEG 3000 is used in cosmetic applications as an emulsifier, lubricant, and moisturizer.
Polyethylene glycol 3000 is found in many personal care products, including lotions, face creams, and shampoos.
3. Food: PEG 3000 is approved for use as a food additive in some countries.
Polyethylene glycol 3000 is used as a thickener, emulsifier, and stabilizer in many food products.
4. Industrial: Polyethylene glycol 3000 is used in metalworking as a lubricant and coolant.
Polyethylene glycol 3000 also serves as a dispersing agent for pigments and dyes in the textile industry.

Chemical uses
Polyethylene glycol 3000 is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Polyethylene glycol 3000 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.
Polyethylene glycol 3000 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, Polyethylene glycol 3000 is used when working with green wood as a stabilizer, and to prevent shrinkage.
Polyethylene glycol 3000 has been used to preserve the painted colors on Terracotta Warriors unearthed at a UNESCO World Heritage site in China.

These painted artifacts were created during the Qin Shi Huang (first emperor of China) era.
Within 15 seconds of the terra-cotta pieces being unearthed during excavations, the lacquer beneath the paint begins to curl after being exposed to the dry Xi'an air.
The paint would subsequently flake off in about four minutes.
The German Bavarian State Conservation Office developed a PEG preservative that when immediately applied to unearthed artifacts has aided in preserving the colors painted on the pieces of clay soldiers.
Polyethylene glycol 3000 is often used (as an internal calibration compound) in mass spectrometry experiments, with its characteristic fragmentation pattern allowing accurate and reproducible tuning.
Polyethylene glycol 3000 derivatives, such as narrow range ethoxylates, are used as surfactants.
Polyethylene glycol 3000 has been used as the hydrophilic block of amphiphilic block copolymers used to create some polymersomes.
Polyethylene glycol 3000 is a component of the propellent used in UGM-133M Trident II Missiles, in service with the United States Navy.
Polyethylene glycol 3000 has been used as a solvent for aryl thioether synthesis.

Manufacturing Process
Polyethylene glycol 3000 was obtained by polymerization of ethylene oxide in an autoclave at 80-100°C using as a catalyst dipotassium alcogolate of Polyethylene glycol 3000.
Dipotassium alcogolate of polyethylene glycol 400 was synthesized by a heating of the dry mixture of Polyethylene glycol 3000 and potassium hydroxide.
The molecular weight of polymer was regulated by the ratio of monomer:catalyst.
POLYETHYLENE GLYCOL 3500
Polyethylene glycol 3350 is used to treat occasional constipation.
Polyethylene glycol 3350 works by holding water in the stool to soften the stool and increases the number of bowel movements.
Polyethylene glycol 3350 is known as an osmotic-type laxative.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

Average molecular weightsrange from 200 to 6000.
Properties vary with molec-ular weight.
Polyethylene glycol 3350 helps in the purification and crystal growth of proteins and nucleic acids.
Polyethylene glycol 3350 also interacts with cell membrane, thereby allowing cell fusion.
Polyethylene glycol 3350 are made of condensed ethylene oxide and water.
They are widely used in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.
Polyethylene glycol 3350 is a semi-solid polyethylene glycol that provides enhanced solvency, lubricity, hygroscopicity and other important functional properties in a wide range of formulations.
Polyethylene glycol 3350 is completely soluble in water with low toxicity and is molecularly stable and non-volatile.

Polyethylene glycol 3350 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: Polyethylene glycol 3350 (25322-68-3)
EPA Substance Registry System: Polyethylene glycol 3350 (25322-68-3)

Biological uses
An example study was done using Polyethylene glycol 3350-diacrylate hydrogels to recreate vascular environments with the encapsulation of endothelial cells and macrophages.
This model furthered vascular disease modeling and isolated macrophage phenotype's effect on blood vessels.
Polyethylene glycol 3350 is commonly used as a crowding agent in in vitro assays to mimic highly crowded cellular conditions.
Although polyethylene glycol is considered biologically inert, Polyethylene glycol 3350 can form non-covalent complexes with monovalent cations such as Na+, K+, Rb+, and Cs+, affecting equilibrium constants of biochemical reactions.
Polyethylene glycol 3350 is commonly used as a precipitant for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of the proteins.
Polyethylene glycol 3350 is used to fuse two different types of cells, most often B-cells and myelomas in order to create hybridomas.

César Milstein and Georges J. F. Köhler originated this technique, which they used for antibody production, winning a Nobel Prize in Physiology or Medicine in 1984.
In microbiology, PEG precipitation is used to concentrate viruses.
Polyethylene glycol 3350 is also used to induce complete fusion (mixing of both inner and outer leaflets) in liposomes reconstituted in vitro.
Gene therapy vectors (such as viruses) can be Polyethylene glycol 3350-coated to shield them from inactivation by the immune system and to de-target them from organs where they may build up and have a toxic effect.
The size of the Polyethylene glycol 3350 polymer has been shown to be important, with larger polymers achieving the best immune protection.
Polyethylene glycol 3350 is a component of stable nucleic acid lipid particles (SNALPs) used to package siRNA for use in vivo.

In blood banking, Polyethylene glycol 3350 is used as a potentiator to enhance detection of antigens and antibodies.
When working with phenol in a laboratory situation, Polyethylene glycol 3350 can be used on phenol skin burns to deactivate any residual phenol.
In biophysics, Polyethylene glycol 3350 is the molecules of choice for the functioning ion channels diameter studies, because in aqueous solutions they have a spherical shape and can block ion channel conductance.

Commercial uses
Polyethylene glycol 3350 is the basis of many skin creams (as cetomacrogol) and personal lubricants.
Polyethylene glycol 3350 is used in a number of toothpastes as a dispersant.
In this application, Polyethylene glycol 3350 binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Polyethylene glycol 3350 is under investigation for use in liquid body armor, and in tattoos to monitor diabetes.
Polymer segments derived from Polyethylene glycol 3350 polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions.
In low-molecular-weight formulations (e.g. PEG 400), Polyethylene glycol 3350 is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
Polyethylene glycol 3350 is used as an anti-foaming agent in food and drinks – its INS number is 1521 or E1521 in the EU.

Purification Methods
Polyethylene glycol 3350 is available commercially as a powder or as a solution in various degrees of polymerization depending on the average molecular weight, e.g. PEG 400 and PEG 800 have average molecular weights of 400 and 800, respectively.
They may be contaminated with aldehydes and peroxides.
Solutions deteriorate in the presence of air due to the formation of these contaminants.
Methods available for purification are as follows: Procedure A: A 40% aqueous solution of PEG 400 (2L, average molecular weight 400) is de-aerated under vacuum and made 10mM in sodium thiosulfate.
After standing for 1hour at 25o, the solution is passed through a column (2.5x20cm) of mixed-bed R-208 resin which has a 5cm layer of Dowex 50-H+ at the bottom of the column.
The column was previously flushed with 30% aqueous MeOH, then thoroughly with H2O.
A flow rate of 1mL/minute is maintained by adjusting the fluid head.
The first 200mL are discarded, and the effluent is then collected at an increased flow rate.

The concentration of Polyethylene glycol 3350 is checked by density measurement, and it is stored (preferably anaerobically) at 15o.
Procedure B: A solution of PEG 800 (500g in 805mL H2O) is made 1mM in H2SO4 and stirred overnight at 25o with 10g of treated Dowex 50-H+ (8% crosslinked, 20-50 mesh).
The resin, after settling, is filtered off on a sintered glass funnel.
The filtrate is treated at 25o with 1.5g of NaBH4 (added over a period of 1minute) in a beaker with tight but removable lid through which a propeller-type mechanical stirrer is inserted and continuously flushed with N2.
After 15minutes, 15g of fresh Dowex 50-H+ are added, and the rate of stirring is adjusted to maintain the resin suspended.
The addition of an equal quantity of Dowex 50-H+ is repeated and the reaction times are 30 and 40minutes.
The pH of a 1 to 10 dilution of the reaction mixture should remain above pH 8 throughout.

If Polyethylene glycol 3350 does not, more NaBH4 is added or the addition of Dowex 50-H+ is curtailed.
(Some samples of PEG can be sufficiently acidic, at least after the hydrolysis treatment, to produce a pH that is too low for efficient reduction when the above ratio of NaBH4 to Dowex 50-H+ is used.)
About 30minutes after the last addition of NaBH4, small amounts of Dowex 50-H+ (~0.2g) are added at 15minute intervals until the pH of a 1 to 10 dilution of the solution is less than 8.
After stirring for an additional 15minutes the resin is allowed to settle, and the solution is transferred to a vacuum flask for brief de-gassing under a vacuum.
The de-gassed solution is passed through a column of mixed-bed resin as in procedure A.
The final Polyethylene glycol 3350 concentration would be about 40% w/v.
Assays for aldehydes by the purpural method and of peroxides are given in the reference below.
Treatment of Dowex 50-H+ (8% crosslinked, 20-50 mesh): The Dowex (500g) is suspended in excess 2N NaOH, and 3mL of liquid Br2 is stirred into the solution.
After the Br2 has dissolved, the treatment is repeated twice, and then the resin is washed with 1N NaOH on a sintered glass funnel until the filtrate is colourless.
The resin is then converted to the acid form (with dilute HCl, H2SO4 or AcOH as required) and washed thoroughly with H2O and sucked dry on the funnel.
The treated resin can be converted to the Na salt and stored.
POLYETHYLENE GLYCOL 35000
SYNONYMS 1,2-Propanediol, Propylene glycol;;Macrogol;Macrogol 3350;Macrogol 4000;Macrogol 6000;PEG;Polyethylene glycol 3350;Polyethylene glycol 4000;Polyethylene glycol 6000 CAS NO:57-55-6
POLYETHYLENE GLYCOL 400
Polyethylene glycol 400 is a type of polyethylene glycol, which is a polymer made from ethylene oxide and water.
Polyethylene glycol 400 is a clear, colorless, and odorless liquid that is used in a variety of applications due to its properties as a solvent, plasticizer, surfactant, and lubricant.
Polyethylene glycol 400 is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.

CAS Number: 25322-68-3
EINECS Number: 500-038-2

Synonyms: Polyethylene Glycol 400, B697894SGQ, PEG-400, Peg 400, 225-856-4, BLINK TRIPLE CARE, PEG-8, Polyethylene glycol 8, Visine Dry Eye Relief, blink gel tears, blink tears, BOTANIPEG 400, CARBOWAX PEG 400, EINECS 225-856-4, Foster and Thrive Dry Eye Relief, HETOXIDE EG-400, JEECHEM 400, LIPO POLYGLYCOL 400, LIPOXOL 400 MED, LUMULSE PEG 400, Lightening Day Cream, Moderate lubricating drops, Moderate lubricating dropsCVS Health, NSC-152325, NSC-155081, NSC-32853, NSC-32854, NSC-32855, NSC-32856, NSC-35744, NSC-35745, NSC-35746, NSC-35747, NSC-35748, NSC-35749, NSC-57859, PLURACARE E 400, POLYETHYLENE GLYCOL 400 (II), POLYETHYLENE GLYCOL 400 (USP-RS), POLYGLYKOL 400, PROTACHEM 400, SYMPATENS-PEG/400, TOHO PEG NO. 400, UNIPEG-400 X, UPIWAX 400, Visine Dry Eye ReliefEye Drops

Polyethylene glycol 400 is strongly hydrophilic.
The partition coefficient of Polyethylene glycol 400 between hexane and water is 0.000015 (log𝑃=−4.8{\displaystyle P=-4.8}), indicating that when Polyethylene glycol 400 is mixed with water and hexane, there are only 15 parts of Polyethylene glycol 400 in the hexane layer per 1 million parts of PEG 400 in the water layer.
Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol.

Polyethylene glycol 400 is soluble in water, acetone, alcohols, benzene, glycerin, glycols, and aromatic hydrocarbons.
Polyethylene glycol 400 is not miscible with aliphatic hydrocarbons and diethyl ether.
Therefore, reaction products can be extracted from the reaction media with those solvents.

Polyethylene glycol 400 is a polymer which is hydrolyzed by ethylene oxide.
Polyethylene glycol 400 has no toxicity and irritation.
Polyethylene glycol 400 is widely used in various pharmaceutical preparations.

The toxicity of low molecular weight Polyethylene glycol 400 is relatively large.
In general, the toxicity of diols is very low.
Topical application of Polyethylene glycol 400, especially mucosal drug, can cause irritant pain.

In topical lotion, Polyethylene glycol 400 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
Diarrhoea can occur in large doses of oral administration.
In injection, the maximum polyethylene glycol 300 concentration is about 30% (V/V).

Polyethylene glycol 400 is a non-ionic hydrophilic polymer and is available in different molecular weights.
Polyethylene glycol 400 either exists in the form of a linear or branched structure.
Polyethylene glycol 400 aids in the purification and crystal growth of proteins and nucleic acids.

Polyethylene glycol 400 along with dextran is used to achieve an aqueous polymer two-phase system, which is essential for the purification of biological materials.
Polyethylene glycol 400 permits cell fusion through its interaction with the cell membrane.
Polyethylene glycol 400 has been used in the production of monoclonal antibodies.

Polyethylene glycol 400, NF acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.
All SpectrumPolyethylene glycol 400 grade products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP).
The low-molecular weight liquid Polyethylene glycol 400 is an excellent solvent for a large number of substances that do not readily dissolve in water.

They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations.
Polyethylene glycol 400 is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power.
However, equilibrium constants for complex formation vary considerably from one substance to another, and certain drugs such as Penicillin G and Bacitracin can even become inactivated.

The effect of the Polyethylene glycol 400 on the efficacy and absorbtion of a drug must therefore always be determined in tests.
With regard to incompatible substances, please see the remarks in the European Pharmacopoeia, Vol. II/3, Monographs M1, Macrogol 300, p. 3.
Polyethylene glycol 400s can also be used to adjust the viscosity of liquid pharmaceutical preparations and ointments, to modify their absorption properties and to stabilise the preparation.

Polyethylene glycol 400 are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions.
Because many Polyethylene glycol 400 types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations.
Polyethylene glycol 400, along with their many nonionic derivatives, are widely utilized in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.

Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.
Polyethylene glycol 400 is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Polyethylene glycol 400 is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye 7.

Polyethylene glycol 400 indicates that the average molecular weight of the specific PEG is 400 10.
PEGylation occurs when Polyethylene glycol 400 are attached to numerous protein medications, allowing for greater solubility for selected drugs.
Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim.

In addition, Polyethylene glycol 400 is available as a bowel preparation for colonoscopy procedures and as a laxative 10.
Polyethylene glycol 400 are a family of linear polymers formed by a base-catalyzed condensation reaction with repeating ethylene oxide units being added to ethylene.
The molecular formula is (C2H4O)multH2O where mult denotes the average number of oxyethylene groups.

The molecular weight can range from 200 to several million corresponding to the number of oxyethylene groups.
The higher-molecular-weight materials (100 000 to 5 000 000) are also referred to as polyethylene oxides.
The average molecular weight of any specific polyethylene glycol product falls within quite narrow limits (°5%).

The number of ethylene oxide units or their approximate molecular weight (e.g., PEG-4 or PEG-200) commonly designates the nomenclature of specific polyethylene glycols.
Polyethylene glycol 400s with amolecular weight less than 600 are liquid, whereas those of molecular weight 1000 and above are solid.
These materials are nonvolatile, water-soluble, tasteless, and odorless.

They are miscible with water, alcohols, esters, ketones, aromatic solvents, and chlorinated hydrocarbons, but immiscible with alkanes, paraffins, waxes, and ethers.
Polyethylene glycol 400 has been indicated for the temporary relief of burning and irritation due to dryness of the eye, andfor protection against further irritation and desiccation 14, 15, 16.
Polyethylene glycol 400 has an average molecular weight of 380 to 420 g/mol.

Polyethylene glycol 400 is soluble in water, alcohol, and many organic solvents.
Polyethylene glycol 400 has a moderate viscosity, making it useful in various formulations.
Polyethylene glycol 400 is generally regarded as safe (GRAS) and is used in pharmaceuticals, cosmetics, and food products.

Polyethylene glycol 400 is used as a solvent and vehicle in liquid medications.
Acts as a base in ointments and creams.
Serves as a plasticizer in tablets and capsules.

Polyethylene glycol 400 is used in skin creams, lotions, shampoos, and conditioners as a moisturizer and thickener.
Acts as a humectant, helping to retain moisture.
Polyethylene glycol 400 serves as a lubricant and mold release agent in rubber and plastic manufacturing.

Polyethylene glycol 400 is used as a coolant and heat transfer fluid.
Polyethylene glycol 400 is used as a food additive and carrier for flavors and colors.
Polyethylene glycol 400 is used as a lubricant for surgical instruments and medical devices.

Polyethylene glycol 400, when used as PEG-400 for eye lubrication provides relief of dry eye symptoms and prevents further irritation, thus protecting the eye from injury 15.
Polyethylene glycol 400 allows comfortable eye drop/natural tear instillation by offering improved spreading of the drop over the ocular surface with diminished blurring 14,15.
Polyethylene glycol 400, depending on molecular weight, has various mechanisms of action 4, 5, 6, 7. For the purpose of Peg-400, the mechanism of action on the eye tissues will be the primary focus of discussion.

Polyethylene glycol 400 is considered a lacrimomimetic, or a synthetic ocular lubricant that improves one or more components of the lacrimal film by augmenting the tear volume and stability and by protecting the eye surface against desiccation 16.
Hydroxypropyl-guar (HPG) is used along with polyethylene glycol 400 (PEG) and propylene glycol (PG) as a gelling agent that conforms to abnormalities of the tear film and existing irregularities on the ocular surface 16.

Polyethylene glycol 400 provides lubrication and acts as a surfactant by coating the eye and interacting with propylene glycol and other solutions that help to act as surfactants on the eye mucosa 15.
This allows for long-lasting, soothing effects 15.
Recent studies involving nanoparticle drug delivery have demonstrated that PEG can achieve sustained drug delivery.

The delivery of drugs to mucosal surfaces is a significant challenge due to the presence of the protective mucus layer that acts to trap and quickly remove foreign particles.
Nanoparticles designed to rapidly cross mucosal barriers (mucus-penetrating particles, “MPP”) have proven promising for augmenting drug distribution, and efficacy at various mucosal surfaces.
Mucus- penetrating particles are heavily coated with Polyethylene glycol 400, protecting the nanoparticle core from adhesion with mucus 17.

Polyethylene glycol 400, when free in solution, may also demonstrate attraction to the surfaces of various types of vesicles, cells or macromolecules, leading to polymer adsorption and subsequently either a repulsion or to an attraction, via bridging, of the surfaces or vesicles—again strongly depending on the temperature, molecular weight, and concentration of the polyethylene glycol.
Low molecular weight polyethylene glycol (such as PEG-400) generally promotes cells or vesicles to adhere (depletion attraction), high molecular weight polyethylene glycol causes them to repel 18.
Polyethylene glycol 400 is used in a variety of pharmaceutical formulations.

Polyethylene glycol 400 finds application in Hewlett-Packard designjet printers as an ink solvent and a lubricant for the print heads.
Polyethylene glycol 400 is an important raw material for the manufacture of polyuretnae, PEG salts of lauric, oleic and stearic acids and latex.
Polyethylene glycol 400 is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable.

Polyethylene glycol 400 is completely soluble in water and has an average molecular weight of 380 - 420.
Polyethylene glycol 400 are another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.
Polyethylene glycol 400 describes polyethylene glycol as being an addition polymer of ethylene oxide and water.

Polyethylene glycol 400 are liquids; grades 1000 and above are solids at ambient temperatures.
Polyethylene glycol 400 occur as clear, colorless or slightly yellow-colored, viscous liquids.
They have a slight but characteristic odor and a bitter, slightly burning taste.

Polyethylene glycol 400 can occur as a solid at ambient temperatures.
Polyethylene glycol 400 are white or off-white in color, and range in consistency from pastes to waxy flakes.
They have a faint, sweet odor. Grades of PEG 6000 and above are available as freeflowing milled powders.

Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol.
Polyethylene glycol 400 is a clear, colorless, viscous liquid. Due in part to its low toxicity, PEG 400 is widely used in a variety of pharmaceutical formulations.
Polyethylene glycol 400 is water-soluble, nonionic, relatively inert, liquids or solids.

Polymer chains are hydroxyl-terminated at both ends.
Polyethylene glycol 400 has a broad molecular weight distribution ranging from ~ 0.5x to 1.5x the values shown.
Because Polyethylene glycol 400 is hydrophilic molecule, it is used to passivate microscope glass slides to prevent non-specific adhesion of proteins in single-molecule fluorescence studies.

Polyethylene glycol 400 is low in toxicity and is used in a variety of products.
Polyethylene glycol 400 is used as a lubricating coating for a variety of surfaces in aqueous and non-aqueous environments.
Because Polyethylene glycol 400 is a flexible, water-soluble polymer, it can be used to create very high osmotic pressures.

Polyethylene glycol 400 is widely used as a polar stationary phase for gas chromatography as well as a heat transfer fluid in electronic test equipment.
Polyethylene glycol 400 is often used in mass spectrometry experiments with its characteristic fragmentation pattern that allows for accurate and reproducible tuning.
Polyethylene glycol 400 derivatives such as narrow-range ethoxylates are used as surfactants.

Polyethylene glycol 400 has been used as the hydrophilic block of amphiphilic block copolymers used to form some polymers.
Polyethylene glycol 400 is the basis of a number of laxatives.
Polyethylene glycol 400 is commonly used as a crowding agent in in vitro experiments to mimic highly populated cellular conditions.

Polyethylene glycol 400 is commonly used as a precipitate for plasmid DNA isolation and protein crystallization.
X-ray diffraction of protein crystals can reveal the atomic structure of proteins.
Polyethylene glycol 400 is used to fuse two different types of cells, mostly B-cells and myelomas, to form hybridomas.

Polymer fragments derived from Polyethylene glycol 400 polyols add flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam pillows.
Polyethylene glycol 400 precipitation is used to concentrate viruses.
Gene therapy vectors (such as viruses) are coated with Polyethylene glycol 400 to protect them from inactivation by the immune system, and can remove them from organs and prevent them from being targeted where they can exert toxic effects.

Dimethyl ethers of Polyethylene glycol 400 are the key component of Selexol, a solvent used by coal combustion, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the gas waste stream.
Polyethylene glycol 400 has been used as a gate insulator in an electric double layer transistor to induce superconductivity in an insulator.
Polyethylene glycol 400 is also used as a polymer host for solid polymer electrolytes.

Although not yet in commercial production, many groups around the world are researching solid polymer electrolytes containing
Polyethylene glycol 400 to improve their properties and allow other products to be used in batteries, electrochromic display systems and other products. future.
Polyethylene glycol 400 is injected into industrial processes to reduce foaming in separation equipment.

Polyethylene glycol 400 is used as a binder in the preparation of technical ceramics.
Polyethylene glycol 400 is the basis of many skin creams (as cetomacrogol) and personal lubricants (often combined with glycerin).
Polyethylene glycol 400 is used as a dispersant in a number of toothpastes.

In this application, Polyethylene glycol 400 binds water and helps keep the xanthan gum evenly distributed throughout the toothpaste.
Polyethylene glycol 400 is also being researched in body armor and tattoos used to monitor diabetes.
Polyethylene glycol 400 belongs to the group of polyoxyethylene glycols.

Polyethylene glycol 400 is a colourless liquid, well soluble in water.
Polyethylene glycol 400 is characterized by strong hygroscopic properties.
Polyethylene glycol 400 exhibits excellent dissolution capacity of the active ingredients.

Polyethylene glycol 400 is characterized by a wide range of applications.
Polyethylene glycol 400 has excellent softening, lubricating, solubilizing, moisturizing and anti-electrostatic properties.
Polyethylene glycol 400 is a polyether compound derived from petroleum with many applications from industrial production to pharmaceuticals.

Polyethylene glycol 400 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE) depending on its molecular weight.
The Polyethylene glycol 400 structure is usually expressed as H−(O−CH2−CH2) n−OH.
Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.

Polyethylene glycol 400 is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Polyethylene glycol 400 is used in ophthalmic solutions for the relief of burning, irritation and/or discomfort that follows dryness of the eye.
Polyethylene glycol 400 indicates that the average molecular weight of the specific PEG is 400.

Polyethylene glycol 400 is a clear liquid with an average molecular weight of 400.
Polyethylene glycol 400 is soluble in water and other polar organic solvents.
Polyethylene glycol 400 is useful in a wide variety of applications including lubricants, plastics, paper, pharmaceuticals, personal care, and food industries.

Polyethylene glycol 400 is useful as a viscosity modifier, plasticizer, and heat transfer agent in many industrial applications.
Because it its humectant properties, Polyethylene glycol 400 can be used in many personal care formulations for ointments and creams.
Polyethylene glycol 400 is also used in gelatin capsules as liquid carriers.

Because of Polyethylene glycol 400’s hydroxyl groups, it can also be used as a chemical intermediate.
The low-molecular weight liquid Polyethylene glycol 400 is an excellent solvent for a large number of substances that do not readily dissolve in water.
They are therefore widely used as solvents and solubilising agents for active substances and excipients in liquid and semi-solid preparations.

Polyethylene glycol 400 is the ability of PEGs to form complexes with active substances that is responsible for their excellent solvent power.
Polyethylene glycol 400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances.
Polyethylene glycol 400 is widely used in a variety of pharmaceutical formulations.

Polyethylene glycol 400 diacrylate.
Polyethylene glycol 400 is water soluble and has low profile.
Polyethylene glycol 400 is able to form a flexible curing film.

Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: refractive index: n20/D 1.469
Flash point: 270 °C
storage temp.: 2-8°C
solubility H2O: 50 mg/mL, clear, colorless
form: waxy solid
color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Viscosity: 1,650-3,850cp (1% solution @ 25C)
Viscosity: 11cs (99C)
Viscosity: 4.5cs (99C)
Viscosity: 5,500-8,000cp (1% solution @ 25C)
Viscosity: 6cs (99C)
Viscosity: 7.4cs (99C)
Viscosity: 750cp (5% solution @ 25C)
Viscosity: 75cp (5% solution @ 25C)
Viscosity: 8,000cs (99C)
Viscosity: 8,800-17,600cp (5% solution @ 25C)
Viscosity: 93cs (99C)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax: λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃

The metabolism of Polyethylene glycol 400 involves the oxidation of the alcohol groups located on the PEG to a carboxylic acid.
For example, the diacid and hydroxyl acid metabolites of Polyethylene glycol 400 have been measured in the plasma and urine of burn patients and rabbits and in the bile of cats.
In the isolated guinea pig liver and in rat/guinea pig in vitro, Polyethylene glycol 400 has demonstrated to be sulfated.

Evidence from experiments with Polyethylene glycol 400 suggests that ethylene glycol is not formed as a metabolite of PEG in humans.
Negligible amounts of oxalic acid are liberated after the metabolism of PEG 12.
The first phase of metabolism of PEG in mammals is regulated by the enzyme alcohol dehydrogenase.

Liver cytochorome Polyethylene glycol 400 enzymes may also play a role in the oxidation of PEG, although the evidence for this is not clear 12.
Also, Polyethylene glycol 400 has been shown to be metabolized by sulfotransferase enzymes.
Although there is evidence that Polyethylene glycol 400 can be metabolized to various phase 1 and phase 2 metabolites, the toxicology data presented above indicate that these metabolites are of very little toxicological concern.

However, metabolism of Polyethylene glycol 400 to the acid metabolite(s) has been implicated in the acidosis and hypercalcemia observed in patients after overdose 12.
Polyethylene glycol 400 is clear that these metabolites can be formed in multiple toxicology species and that the phase 1 metabolites are seen in animals and humans.
These data indicate that humans and animals will be exposed to similar metabolites after administration of PEG 12.

Metabolic clearance of Polyethylene glycol 400 decreases markedly as molecular weight increases.
Polyethylene glycol 400, up to 25% of the dose may be metabolized in humans (Schaffer et al., 1950); similar results are also seen in the rabbit 12.
Polyethylene glycol 400 by the oral route is molecular weight- dependent.

Urinary recovery data for PEG400 indicate that 50 to 60% of Polyethylene glycol 400 with this molecular weight is absorbed from the intestine 12.
In the case of Polyethylene glycol 400, up to 25% of the dose may be metabolized in humans.
Polyethylene glycol 400 is also known as polyoxirane (PEO).

Polyethylene glycol 400 is a linear polyether obtained by ring opening polymerization of ethylene oxide.
The viscosity of polyethylene glycol solution is sensitive to the shear rate and it is not easy for bacteria to grow on polyethylene glycol.
The condensation polymer of ethylene oxide and water.

Polyethylene glycol 400 is a cream matrix for preparing water-soluble drugs.
Polyethylene glycol 400 can also be used as a solvent for acetylsalicylic acid and caffeine, which is difficult to dissolve in water.
Drug sustained-release and immobilized enzyme carrier.

The polyethylene glycol solution is applied to the outer layer of the pill to control the diffusion of drugs in the pill so as to improve the efficacy.
Surface modification of medical polymer materials.
The biocompatibility of medical polymer materials in contact with blood can be improved by adsorption, interception and grafting of two amphiphilic copolymers containing Polyethylene glycol 400 on the surface of medical polymers.

Polyethylene glycol 400 can make the membrane of the alkanol contraceptive pill.
Polyethylene glycol 400 can make hydrophilic anticoagulant polyurethane.
Polyethylene glycol 400 is an osmotic laxative.

Polyethylene glycol 400 can increase osmotic pressure and absorb moisture in the intestinal cavity, which makes the stool soften and increase in volume, resulting in bowel movement and defecation.
Polyethylene glycol 400 nontoxic and gelatinous nature can be used as a component of denture fixer.
Polyethylene glycol 400 are commonly used to promote cell fusion or protoplast fusion and help organisms (such as yeasts) to take DNA in transformation.

Polyethylene glycol 400 absorbs water from the solution, so it is also used to concentrate the solution.
Polyethylene glycol 400 is a clear, colorless liquid that is made from sugar cane waste so it is naturally derived and renewable.
Polyethylene glycol 400 is completely soluble in water and has an average molecular weight of 380 - 420.

Polyethylene glycol 400 is another group of products with an incredibly long list of uses and applications from industrial uses to food and pharma, and everything in between.
Polyethylene glycol 400 is a high quality research product used as multipurpose polymer of ethelyne glycol for various biochemical, molecular biology and molecular diagnostic applications.
Polyethylene glycol 400 is a polyether compound with many applications from industrial manufacturing to medicine.

Applications of Polyethylene glycol 400 include uses in cosmetics, personal care products in which it is used as a solvent and humectant.
Polyethylene glycol 400 is used in a wide range of lubricant applications due to their low volatility, solubility in water, and natural lubricity
The ring-opening polymerization of ethylene oxide is readily effected by a variety of ionic reagents and several types of polymer have been prepared.

For commercial purposes, poly(ethylene oxide)s of low molecular weight and of very high molecular weight are of interest.
Polyethylene glycol 400s of low molecular weight, i.e. below about 3000, are generally prepared by passing ethylene oxide into Polyethylene glycol 400 and about 0.3 MPa (3 atmospheres) pressure, using an alkaline initiator such as sodium hydroxide.

The polymers produced by these methods are thus terminated mainly by hydroxy groups (a few unsaturated end-groups are also formed) and are often referred to as poly(ethylene glycol)s.
Polyethylene glycol 400s with molecular weights in the range 200-600 are viscous liquids which find use as surfactants in inks and paints and as humectants.
At molecular weights above about 600, poly(ethylene glycol)s are low-melting waxy solids, uses of which include pharmaceutical and cosmetic bases, lubricants and mould release agents.

Polyethylene glycol 400 may be noted that homogeneous cationic polymerization of ethylene oxide also generally leads to low molecular weight products; typical initiators include aluminium chloride, boron trifluoride and titanium tetrachloride.
Systems of this type are not utilized on a commercial scale.
Polyethylene glycol 400s of molecular weight ranging from about 100000 to 5 x 106 and above are available.
Details of the techniques used to manufacture these polymers have not been disclosed, but the essential feature is the use of (generally) heterogeneous initiator systems.

Effective initiators are mainly of two types, namely alkaline earth compounds (e.g. carbonates and oxides of calcium, barium and strontium) and organometallic compounds (e.g. aluminium and zinc alkyls and alkoxides, commonly with added coinitiators).
The precise modes of action of these initiators have not, as yet, been fully resolved.
However, Polyethylene glycol 400 is now generally thought that polymerization occurs through a co-ordinated anionic mechanism, in which the ethylene oxide is coordinated to the initiator through an unshared electron pair on the oxirane oxygen atom.

Unlike the low molecular weight poly(ethylene oxide)s, the high molecular weight polymers are tough and extensible.
They are highly crystalline, with a melting point of 66??C.
Unlike most water-soluble polymers, the high molecular weight poly(ethylene oxide)s may be melt processed; they may be injection moulded, extruded and calendered without difficulty.

Polyethylene glycol 400s are soluble in an unusually broad range of solvents, which includes water; chlorinated hydrocarbons such as carbon tetrachloride and methylene dichloride; aromatic hydrocarbons such as benzene and toluene; ketones such as acetone and methyl ethyl ketone; and alcohols such as methanol and isopropanol.
There is an upper temperature limit of solubility in water for the high molecular weight poly(ethylene oxide)s; this varies with concentration and molecular weight but is usually between 90 and 100??C.

Water-solubility is due to the ability of the polyether to form hydrogen bonds with water; these bonds are broken when the temperature is raised, restoring the anhydrous polymer which is precipated from the solution.
High molecular weight poly(ethylene oxide)s find use as water-soluble packaging films and capsules for such products as laundry powders, colour concentrates, tablets and seeds.
In solution, the polymers are used as thickeners in pharmaceutical and cosmetic preparations, textile sizes and latex stabilizers.

Dissolves many drugs and active ingredients to form clear, stable solutions.
Polyethylene glycol 400 is used in drug formulations to ensure the stability and bioavailability of the active ingredients.
Polyethylene glycol 400 is used in over-the-counter laxative products like MiraLAX, aiding in bowel movements by retaining water in the stool.

Provides a smooth and soft texture to creams and lotions, enhancing their spreadability.
Helps bind together ingredients in solid products like pressed powders and tablets.
Helps active ingredients penetrate the skin more effectively.

Reduces friction between moving parts in machinery and industrial processes.
Polyethylene glycol 400 improves the flexibility and durability of plastics and resins.
Polyethylene glycol 400 reduces static electricity buildup in manufacturing processes involving plastics and textiles.

Polyethylene glycol 400 is used in products like candy and confectionery to maintain moisture and improve texture.
Helps evenly distribute flavors, colors, and other additives in food products.
Facilitates the smooth operation of surgical instruments and reduces wear and tear.

Polyethylene glycol 400 is used to coat medical devices to reduce friction and improve biocompatibility.
Polyethylene glycol 400 is generally recognized as safe by regulatory agencies such as the FDA.
Non-toxic when used in appropriate amounts, but excessive ingestion can lead to gastrointestinal disturbances.

Biodegradable, but high concentrations in water bodies can affect aquatic life.
Polyethylene glycol 400 is used as a carrier for pesticides and herbicides to improve their effectiveness.
Acts as a dispersing agent and helps improve the flow and leveling properties of paints.

Enhances the performance of adhesives by improving flexibility and reducing brittleness.
Should be stored in a cool, dry place away from direct sunlight and moisture.
Generally safe to handle, but standard precautions such as wearing gloves and safety goggles are recommended.

Polyethylene glycol 400 was obtained by polymerization of ethylene oxide in an autoclave at 80-100°C using as a catalyst dipotassium alcogolate of polyethylene glycol 400.
Dipotassium alcogolate of polyethylene glycol 400 was synthesized by a heating of the dry mixture of polyethylene glycol 400 and potassium hydroxide.
The molecular weight of polymer was regulated by the ratio of monomer:catalyst.

Uses:
Polyethylene glycol 400 is a condensation polymers of ethylene oxide and water with the general formula H(OCH2CH2)nOH, where n is the average number of repeating oxyethylene groups typically from 4 to about 180.
The low molecular weight members from n=2 to n=4 are diethylene glycol, triethylene glycol and tetraethylene glycol respectively, which are produced as pure compounds.
The low molecular weight compounds upto 700 are colorless, odorless viscous liquids with a freezing point from -10 C (diethylene gycol), while polymerized compounds with higher molecular weight than 1,000 are waxlike solids with melting point upto 67 C for n 180.

The abbreviation Polyethylene glycol 400 is termed in combination with a numeric suffix which indicates the average molecular weights.
One common feature of Polyethylene glycol 400 appears to be the water-soluble.
Polyethylene glycol 400 is soluble also in many organic solvents including aromatic hydrocarbons (not aliphatics).

They are used to make emulsifying agents and detergents, and as plasticizers, humectants, and water-soluble textile lubricants.
The wide range of chain lengths provide identical physical and chemical properties for the proper application selections directly or indirectly in the field of; Alkyd and polyester resin preparation to enhance water dispersability and water-based coatings.
Antidusting agent in agricultural formulations Brightening effect and adhesion enhance in electroplating and electroplating process.

Cleaners, detergents and soaps with low volatility and low toxicity solvent properties.
Coupling agent, humectant, solvent and lubricant in cosmetics and personal care bases.
Dimensional stabilizer in wood working operations Dye carrier in paints and inks Heat transfer fluid formulation and defoamer formulations.

Polyethylene glycol 400 low volatilie, water soluble, and noncorrosive lubricant without staining residue in food and package process.
Polyethylene glycol 400 mold release agent and lubricant in fabricating elastomers Paper coating for antisticking, color stabilizing, good gloss and free flow in calendering operations.
Plasticizer to increase lubricity and to impart a humectant property in ceramic mass, adhesives and binders.

Softener and antistatic agent for textiles Soldering fluxes with good spreading property.
Polyethylene glycol is non-toxic, odorless, neutral, lubricating, nonvolatile and nonirritating and is used in a variety of pharmaceuticals and in medications as a solven, dispensing agent, ointment and suppository bases, vehicle, and tablet excipient.
Polyethylene glycol 400 molecules of approximately 2000 monomers.

Polyethylene glycol 400 is used in various applications from industrial chemistry to biological chemistry.
Recent research has shown Polyethylene glycol 400 m aintains the ability to aid the spinal cord injury recovery process, helping the nerve impulse conduction process in animals.
In rats, it has been shown to aid in the repair of severed sciatic axons, helping with nerve damage recovery.

Polyethylene glycol 400 is industrially produced as a lubricating substance for various surfaces to reduce friction.
Polyethylene glycol 400 is also used in the preparation of vesicle transport systems in with application towards diagnostic procedures or drug delivery methods.
Polyethylene glycol 400 is a binder, coating agent, dispersing agent, flavoring adjuvant, and plasticizing agent that is a clear, colorless, viscous, hygroscopic liquid resembling paraffin (white, waxy, or flakes), with a ph of 4.0–7.5 in 1:20 concentration.

Polyethylene glycol 400 is soluble in water (mw 1,000) and many organic solvents.
Polyethylene glycol 400 is a binder, solvent, plasticizing agent, and softener widely used for cosmetic cream bases and pharmaceutical ointments.
Polyethylene glycol 400 are quite humectant up to a molecular weight of 500.

Beyond this weight, their water uptake diminishes.
Polyethylene glycol 400 is used in conjunction with carbon black to form a conductive composite.
Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.

This medication is used to relieve dry, irritated eyes.
Common causes for dry eyes include wind, sun, heating/air conditioning, computer use/reading, and certain medications.
Polyethylene glycol 400 may contain 1 or more of the following ingredients: carboxymethylcellulose, dextran, glycerin, hypromellose, polyethylene glycol 400 (PEG 400), polysorbate, polyvinyl alcohol, povidone, or propylene glycol, among others.

Eye lubricants keep the eye moist, help to protect the eye from injury and infection, and decrease symptoms of dry eyes such as burning, itching, and feeling as if something is in the eye.
Polyethylene glycol 400 are widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations.
Polyethylene glycol 400 has been used experimentally in biodegradable polymeric matrices used in controlled-release systems.

Polyethylene glycol 400 are stable, hydrophilic substances that are essentially nonirritant to the skin;They do not readily penetrate the skin, although the polyethylene glycols are water-soluble and are easily removed from the skin by washing, making them useful as ointment bases.
Solid grades are generally employed in topical ointments, with the consistency of the base being adjusted by the addition of liquid grades of polyethylene glycol.
Mixtures of polyethylene glycols can be used as suppository bases,for which they have many advantages over fats.

For example, the melting point of the suppository can be made higher to withstand exposure to warmer climates; release of the drug is not dependent upon melting point; the physical stability on storage is better; and suppositories are readily miscible with rectal fluids.
Polyethylene glycol 400 have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the polyethylene glycol; and polyethylene glycols tend to be more irritating to mucous membranes than fats.

Aqueous Polyethylene glycol 400 solutions can be used either as suspending agents or to adjust the viscosity and consistency of other suspending vehicles.
When used in conjunction with other emulsifiers, Polyethylene glycol 400 can act as emulsion stabilizers.
Liquid polyethylene glycols are used as water-miscible solvents for the contents of soft gelatin capsules.

However, they may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in the shell.
In concentrations up to approximately 30% v/v, PEG 300 and Polyethylene glycol 400 have been used as the vehicle for parenteral dosage forms.
In solid-dosage formulations, higher-molecular-weight Polyethylene glycol 400 can enhance the effectiveness of tablet binders and impart plasticity to granules.

However, they have only limited binding action when used alone, and can prolong disintegration if present in concentrations greater than 5% w/w.
When used for thermoplastic granulations,a mixture of the powdered constituents with 10–15% w/w PEG 6000 is heated to 70–75°C.
The mass becomes pastelike and forms granules if stirred while cooling.

This technique is useful for the preparation of dosage forms such as lozenges when prolonged disintegration is required.
Polyethylene glycol 400 can also be used to enhance the aqueous solubility or dissolution characteristics of poorly soluble compounds by making solid dispersions with an appropriate polyethylene glycol.
Animal studies have also been performed using polyethylene glycols as solvents for steroids in osmotic pumps.

In film coatings, solid grades of Polyethylene glycol 400 can be used alone for the film-coating of tablets or can be useful as hydrophilic polishing materials.
Solid grades are also widely used as plasticizers in conjunction with film-forming polymers.
The presence of Polyethylene glycol 400 in film coats, especially of liquid grades, tends to increase their water permeability and may reduce protection against low pH in enteric-coating films.

Polyethylene glycol 400 are useful as plasticizers in microencapsulated products to avoid rupture of the coating film when the microcapsules are compressed into tablets.
Polyethylene glycol 400 grades with molecular weights of 6000 and above can be used as lubricants, particularly for soluble tablets.
The lubricant action is not as good as that of magnesium stearate, and stickiness may develop if the material becomes too warm during compression.

An antiadherent effect is also exerted, again subject to the avoidance of overheating.
Polyethylene glycol 400 have been used in the preparation of urethane hydrogels, which are used as controlled-release agents.
Polyethylene glycol 400 has also been used in insulin-loaded microparticles for the oral delivery of insulin;it has been used in inhalation preparations to improve aerosolization;polyethylene glycol nanoparticles have been used to improve the oral bioavailability of cyclosporine;it has been used in self-assembled polymeric nanoparticles as a drug carrier;and copolymer networks of polyethylene glycol grafted with poly(methacrylic acid) have been used as bioadhesive controlled drug delivery formulations.

Polyethylene glycol 400 is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointment and suppository base, and tablet and capsule lubricant.
Polyethylene glycol 400 has low toxicity and absorption.
Polyethylene glycol 400 is a low-molecular-weight grade of polyethylene glycol with a low-level toxicity.

Polyethylene glycol 400 is very hydrophilic, which renders it a useful ingredient in drug formulations to augment the solubility and bioavailability of weakly water-soluble drugs.
Dissolves active ingredients in liquid medications.
Stabilizes and enhances the bioavailability of active ingredients.

Polyethylene glycol 400 is used in products like MiraLAX to treat constipation by retaining water in the stool.
Polyethylene glycol 400 improves texture and spreadability.
Used in tablet and capsule formulations to improve flexibility.

Adds smoothness and softness to creams and lotions.
Retains moisture in products like shampoos, conditioners, and skin creams.
Helps solid products like pressed powders and tablets maintain their shape.

Polyethylene glycol 400 increases the absorption of active ingredients through the skin.
Reduces friction in machinery and industrial processes.
Enhances flexibility and durability in plastics and resins.

Minimizes static electricity buildup in plastics and textiles manufacturing.
Polyethylene glycol 400 is used in various industrial cooling applications.
Maintains moisture and improves the texture of products like candy and confectionery.

Distributes flavors, colors, and other additives evenly in food products.
Facilitates the smooth operation of surgical instruments.
Reduces friction and improves biocompatibility of medical devices.

Polyethylene glycol 400 enhances the effectiveness of agricultural chemicals by improving their distribution and absorption.
Improves the flow and leveling properties of paints.
Adjusts the thickness and consistency of coatings.

Polyethylene glycol 400 improves flexibility and reduces brittleness in adhesive formulations.
Polyethylene glycol 400 is used as a solvent and reagent in various chemical and biological experiments.
Included in formulations for personal care products to reduce friction.

Safety Profile:
When heated to decomposition Polyethylene glycol 400 emits acrid smoke and irritating fumes.
Polyethylene glycol 400s are widely used in a variety of pharmaceutical formulations.
Generally, they are regarded as nontoxic and nonirritant materials.

Adverse reactions to Polyethylene glycol 400 have been reported, the greatest toxicity being with glycols of low molecular weight.
However, the toxicity of glycols is relatively low.
Polyethylene glycol 400 administered topically may cause stinging, especially when applied to mucous membranes.

Hypersensitivity reactions to Polyethylene glycol 400 applied topically have also been reported, including urticaria and delayed allergic reactions.
The most serious adverse effects associated with Polyethylene glycol 400 are hyperosmolarity, metabolic acidosis, and renal failure following the topical use of polyethylene glycols in burn patients.
Topical preparations containing polyethylene glycols should therefore be used cautiously in patients with renal failure, extensive burns, or open wounds.

Oral administration of large quantities of Polyethylene glycol 400 can have a laxative effect.
Therapeutically, up to 4 L of an aqueous mixture of electrolytes and high-molecular-weight polyethylene glycol is consumed by patients undergoing bowel cleansing.
Liquid Polyethylene glycol 400 may be absorbed when taken orally, but the higher-molecular-weight polyethylene glycols are not significantly absorbed from the gastrointestinal tract.

Absorbed Polyethylene glycol 400 is excreted largely unchanged in the urine, although polyethylene glycols of low molecular weight may be partially metabolized.
The WHO has set an estimated acceptable daily intake of Polyethylene glycol 400 at up to 10 mg/kg body-weight.
In parenteral products, the maximum recommended concentration of Polyethylene glycol 400 is approximately 30% v/v as hemolytic effects have been observed at concentrations greater than about 40% v/v.

POLYETHYLENE GLYCOL 4000
Polyethylene glycol 4000 is a polyether compound with many applications from industrial manufacturing to medicine.
The structure of Polyethylene glycol 4000 is (note the repeated element in parentheses):
H-(O-CH2-CH2)n-OH
Polyethylene glycol 4000 is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Polyethylene glycol 4000 is used in gene delivery of protoplast transfection and incubation.
Polyethylene glycol 4000 is used in the preparation of extraction for measuring cytosolic phosphoenolpyruvate carboxykinase (PEPCK) from plant tissues.
Polyethylene glycol 4000 is useful to mediate DNA transformation into protoplasts derived from rice leaf sheaths.

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

Polyethylene glycol 4000 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: <0.01 mm Hg ( 20 °C)
Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: Polyethylene glycol 4000 (25322-68-3)
EPA Substance Registry System: Polyethylene glycol 4000 (25322-68-3)

Industrial uses
A nitrate ester-plasticized Polyethylene glycol 4000 is used in Trident II submarine-launched ballistic missile solid rocket fuel.
Dimethyl ethers of Polyethylene glycol 4000 are the key ingredient of Selexol, a solvent used by coal-burning, integrated gasification combined cycle (IGCC) power plants to remove carbon dioxide and hydrogen sulfide from the syngas stream.
Polyethylene glycol 4000 has been used as the gate insulator in an electric double-layer transistor to induce superconductivity in an insulator.
Polyethylene glycol 4000 is used as a polymer host for solid polymer electrolytes.
Although not yet in commercial production, many groups around the globe are engaged in research on solid polymer electrolytes involving Polyethylene glycol 4000, with the aim of improving their properties, and in permitting their use in batteries, electro-chromic display systems, and other products in the future.
Polyethylene glycol 4000 is injected into industrial processes to reduce foaming in separation equipment.
Polyethylene glycol 4000 is used as a binder in the preparation of technical ceramics.
PEG was used as an additive to silver halide photographic emulsions.

Entertainment uses
Polyethylene glycol 4000 is used to extend the size and durability of very large soap bubbles.
Polyethylene glycol 4000 is the main ingredient in many personal lubricants.
(Not to be confused with propylene glycol.)
Polyethylene glycol 4000 is the main ingredient in the paint (known as "fill") in paintballs.

Commercial uses
Polyethylene glycol 4000 is the basis of many skin creams (as cetomacrogol) and personal lubricants.
Polyethylene glycol 4000 is used in a number of toothpastes as a dispersant.
In this application, Polyethylene glycol 4000 binds water and helps keep xanthan gum uniformly distributed throughout the toothpaste.
Polyethylene glycol 4000 is under investigation for use in liquid body armor, and in tattoos to monitor diabetes.
Polymer segments derived from Polyethylene glycol 4000 polyols impart flexibility to polyurethanes for applications such as elastomeric fibers (spandex) and foam cushions.
In low-molecular-weight formulations (e.g. PEG 400), Polyethylene glycol 4000 is used in Hewlett-Packard designjet printers as an ink solvent and lubricant for the print heads.
Polyethylene glycol 4000 is used as an anti-foaming agent in food and drinks – its INS number is 1521 or E1521 in the EU.

Production
The production of Polyethylene glycol 4000 was first reported in 1859.
Both A. V. Lourenço and Charles Adolphe Wurtz independently isolated products that were polyethylene glycols.
Polyethylene glycol 4000 is produced by the interaction of ethylene oxide with water, ethylene glycol, or ethylene glycol oligomers.
The reaction is catalyzed by acidic or basic catalysts.
Ethylene glycol and its oligomers are preferable as a starting material instead of water, because they allow the creation of polymers with a low polydispersity (narrow molecular weight distribution).
Polymer chain length depends on the ratio of reactants.

HOCH2CH2OH + n(CH2CH2O) → HO(CH2CH2O)n+1H
Depending on the catalyst type, the mechanism of polymerization can be cationic or anionic.
The anionic mechanism is preferable because it allows one to obtain Polyethylene glycol 4000 with a low polydispersity.
Polymerization of ethylene oxide is an exothermic process.
Overheating or contaminating ethylene oxide with catalysts such as alkalis or metal oxides can lead to runaway polymerization, which can end in an explosion after a few hours.

Polyethylene oxide, or high-molecular-weight Polyethylene glycol 4000, is synthesized by suspension polymerization.
Polyethylene glycol 4000 is necessary to hold the growing polymer chain in solution in the course of the polycondensation process.
The reaction is catalyzed by magnesium-, aluminium-, or calcium-organoelement compounds.
To prevent coagulation of polymer chains from solution, chelating additives such as dimethylglyoxime are used.

Alkaline catalysts such as sodium hydroxide (NaOH), potassium hydroxide (KOH), or sodium carbonate (Na2CO3) are used to prepare low-molecular-weight Polyethylene glycol 4000.
POLYETHYLENE GLYCOL 4000
PEG 4000 Applications PEG 4000 Application Polyethylene glycol 1500 for synthesis. CAS 25322-68-3, pH 4 - 7 (100 g/l, H₂O, 20 °C). PEG 4000 Physicochemical Information PEG 4000 Boiling point >200 °C (1013 hPa) PEG 4000 Density 1.2 g/cm3 (20 °C) PEG 4000 Flash point 240 °C PEG 4000 Ignition temperature 420 °C PEG 4000 Melting Point 43 - 49 °C PEG 4000 pH value 4 - 7 (100 g/l, H₂O, 20 °C) PEG 4000 Vapor pressure <0.01 hPa (20 °C) PEG 4000 Bulk density 400 - 500 kg/m3 PEG 4000 Solubility 650 g/l PEG 4000 Toxicological Information PEG 4000 LD 50 oral LD50 Rat 28000 mg/kg PEG 4000 LD 50 dermal LD50 Rabbit > 20000 mg/kg PEG 4000 Safety Information according to GHS PEG 4000 Storage class 10 Combustible liquids PEG 4000 WGK WGK 1 slightly hazardous to water PEG 4000 Disposal 3 PEG 4000 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C. PEG 4000 Storage and Shipping Information PEG 4000 Storage Store below +30°C. PEG 4000 Transport Information PEG 4000 Declaration (railroad and road) ADR, RID Kein Gefahrgut PEG 4000 Declaration (transport by air) IATA-DGR No Dangerous Good PEG 4000 Declaration (transport by sea) IMDG-Code No Dangerous Good PEG 4000 Specifications PEG 4000 Melting range (lower value) ≥ 43 °C PEG 4000 Melting range (upper value) ≤ 49 °C PEG 4000 Hydroxyl value 70 - 80 PEG 4000 Average molecular mass 1400 - 1600 PEG 4000 Identity (IR) passes test Activated PEG 4000s (for conjugation to biologics) PEG 4000-PLA or PEG 4000-PLGA (for nanoparticle formulations of drugs) Linear and branched functionalized polyethylene imines and other polyimines (for oligo-nucleotide binding and delivery) PEG 4000-pAsp / PEG 4000-pGlu (for oligo-nucleotide binding and delivery) Hyperbranched polyglycerols (for drug delivery and protein formulation) Other polymers for nanoparticle formation (drug delivery) Poly(ethylene glycol) (PEG 4000) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG 4000 and dextran together result in aqueous polymer two phase system, which is required for the purification of biological materials. PEG 4000 also interacts with cell membrane, thereby allowing cell fusion.Polyethylene Glycol 1500 (PEG 4000-1500) has been used to mediate cell fusion.PEG 4000 is a polymer of ethylene oxide with an average molecular weight of 1500. This polymeric material is an excellent solubiliser and can be used in a wide variety of home care and I&I applications.Polyethylene glycol. PEG- 1500 by Dynamic International is a surfactant. It is available in the form of milky white solid. PEG- 1500 is used in cream and shampoo base material.Crystallization grade Polyethylene glycol 1500(PEG 4000) for formulating screens or for optimization.PEG 4000 Eye contact Unlikely to cause eye irritation in man.PEG 4000 Skin contact Unlikely to cause skin irritation in man.PEG 4000 Inhalation This material may cause irritation following inhalation.PEG 4000 Ingestion Will cause irritation of the gastrointestinal tract.Low oral toxicity, but ingestion may cause irritation of the gastrointestinal tract.PEG 4000 Eye contact Irrigate with eyewash solution or clean water, holding the eyelids apart, for at least 10 minutes. Obtain medical attention.PEG 4000 Skin contact Remove contaminated clothing. Wash skin with soap and water. If symptoms develop, obtain medical attention.PEG 4000 Inhalation Remove patient from exposure. Obtain medical attention if ill effects occur.PEG 4000 Ingestion Do not induce vomiting. Wash out mouth with water and give 200-300 ml (half a pint) of water to drink. Obtain medical attention if ill effects occur.PEG 4000 Further Medical Treatment Symptomatic treatment and supportive therapy as indicated.PEG 4000 Extinguishing Media Water fog, alcohol foam, carbon dioxide, dry chemical.PEG 4000 Unsuitable Extinguishing Media None known.PEG 4000 Special fire-fighting protective equipment A self contained breathing apparatus and suitable protective clothing must be worn in fire conditions.PEG 4000 Fire and explosion hazards Combustible but not readily ignited. PEG 4000 Colour white PEG 4000 Form solid PEG 4000 Odour mild PEG 4000 pH approx 5 - 7 5% In water PEG 4000 Boiling point/boiling range (°C) No data. PEG 4000 Flash Point (ºC) > 260 (open cup) PEG 4000 Autoignition Temperature (ºC) approx 420 PEG 4000 Flammable Limits No data. PEG 4000 Explosive Properties No data. PEG 4000 Oxidising Properties No data. PEG 4000 Vapour Density No data. PEG 4000 Solubility in water soluble PEG 4000 Solubility in other ingredients Soluble in many organic solvents, insoluble in:, aliphatic hydrocarbons PEG 4000 Partition Coefficient No data. PEG 4000 Dynamic viscosity (mPa.s) approx 30 @99°C PEG 4000 Density (g/ml) 1.208 @ 20 °C PEG 4000 Stability Stable under normal conditions. PEG 4000 Materials to avoid Strong oxidising agents. PEG 4000 Conditions to avoid None known PEG 4000 Hazardous decomposition products None known PEG 4000 Hazardous polymerisation Will not occur
POLYETHYLENE GLYCOL 600
Polyethylene glycol 600 is a versatile solvent product with balance properties.
Fast evaporating solvent with high water solubility and active solvency used in a variety of applications such as solvent-based coatings, household and industrial cleaners, and agricultural pesticides​.
Polyethylene glycol 600 is made of condensed ethylene oxide and water.

CAS: 25322-68-3
MF: N/A
EINECS: 500-038-2

Synonyms
1,2-ethanediol,homopolymer;2-ethanediyl),.alpha.-hydro-.omega.-hydroxy-Poly(oxy-1;Alcox E 160;Alcox E 30;alcoxe30;Poly(ethylene oxide),approx. M.W. 600,000;Poly(ethylene oxide),approx. M.W. 200,000;Poly(ethylene oxide),approx. M.W. 900,000;Polyethylene Glycol 600;PEG 600;NL4J9F21N9;CARBOWAX PEG 600;JEECHEM 600;LIPO POLYGLYCOL 600;LIPOXOL 600 MED;MACROGOL 600 DISTEARATE;NORFOX E-600;PEG-12;PLURACARE E 600;POLYETHYLENE GLYCOL 600 (II);POLYETHYLENE GLYCOL 600 (USP-RS);POLYGLYKOL 600;SABOPEG 600;TOHO PEG NO. 600;UNIPEG-600;UPIWAX 600

They are widely used in cosmetic products as surfactants, emulsifiers, cleansing agents, humectants, and skin conditioners.
Polythylene Glycol 600 is a semi-solid polyethylene glycol that provides enhanced solvency, lubricity, hygroscopicity and other important functional properties in a wide range of formulations.
These materials are nonvolatile, water-soluble, tasteless, and odorless.
They are miscible with water, alcohols, esters, ketones, aromatic solvents, and chlorinated hydrocarbons, but immiscible with alkanes, paraffins, waxes, and ethers.
Any of several condensa-tion polymers of ethylene glycol with thegeneral formula HOCH2(CH2OCH2)nCH2OH orH(OCH2CH2)nOH.

Polyethylene glycol 600 Chemical Properties
Melting point: 64-66 °C
Boiling point: >250°C
Tg: -67
Density: 1.27 g/mL at 25 °C
Vapor density: >1 (vs air)
Vapor pressure: Refractive index: n20/D 1.469
Fp: 270 °C
Storage temp.: 2-8°C
Solubility H2O: 50 mg/mL, clear, colorless
Form: waxy solid
Color: White to very pale yellow
Specific Gravity: 1.128
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
λmax λ: 260 nm Amax: 0.6
λ: 280 nm Amax: 0.3
Merck: 14,7568
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: -0.698 at 25℃
NIST Chemistry Reference: Polyethylene glycol 600 (25322-68-3)
EPA Substance Registry System: Polyethylene glycol 600 (25322-68-3)

The toxicity of low molecular weight Polyethylene glycol 600 is relatively large.
In general, the toxicity of diols is very low.
Topical application of Polyethylene glycol 600, especially mucosal drug, can cause irritant pain.
In topical lotion, Polyethylene glycol 600 can increase the flexibility of the skin, and has a similar moisturizing effect with glycerin.
Polyethylene glycol 600 can occur in large doses of oral administration.
In injection, the maximum Polyethylene glycol 600 concentration is about 30% (V/V).
Hemolysis could occur when the concentration is more than 40% (V/V).

Reactivity Profile
Polyethylene glycol 600 is heat-stable and inert to many chemical agents; Poly(ethylene glycol) will not hydrolyze or deteriorate under normal conditions.
Polyethylene glycol 600 has a solvent action on some plastics.

Pharmaceutical Applications
Polyethylene glycol 600 (PEGs) are widely used in a variety of pharmaceutical formulations, including parenteral, topical, ophthalmic, oral, and rectal preparations.
Polyethylene glycol 600 has been used experimentally in biodegradable polymeric matrices used in controlled-release systems.
Polyethylene glycol 600 is stable, hydrophilic substances that are essentially nonirritant to the skin;They do not readily penetrate the skin, although the polyethylene glycols are water-soluble and are easily removed from the skin by washing, making them useful as ointment bases.
Solid grades are generally employed in topical ointments, with the consistency of the base being adjusted by the addition of liquid grades of polyethylene glycol.
Mixtures of Polyethylene glycol 600 can be used as suppository bases,for which they have many advantages over fats.

For example, the melting point of the suppository can be made higher to withstand exposure to warmer climates; release of the drug is not dependent upon melting point; the physical stability on storage is better; and suppositories are readily miscible with rectal fluids.
Polyethylene glycol 600 have the following disadvantages: they are chemically more reactive than fats; greater care is needed in processing to avoid inelegant contraction holes in the suppositories; the rate of release of water-soluble medications decreases with the increasing molecular weight of the Polyethylene glycol 600; and polyethylene glycols tend to be more irritating to mucous membranes than fats.
Aqueous Polyethylene glycol 600 solutions can be used either as suspending agents or to adjust the viscosity and consistency of other suspending vehicles.
When used in conjunction with other emulsifiers, Polyethylene glycol 600 can act as emulsion stabilizers.
Liquid Polyethylene glycol 600 is used as water-miscible solvents for the contents of soft gelatin capsules.
However, they may cause hardening of the capsule shell by preferential absorption of moisture from gelatin in the shell.

In concentrations up to approximately 30% v/v, PEG 300 and PEG 400 have been used as the vehicle for parenteral dosage forms.
In solid-dosage formulations, higher-molecular-weight polyethylene glycols can enhance the effectiveness of tablet binders and impart plasticity to granules.
However, they have only limited binding action when used alone, and can prolong disintegration if present in concentrations greater than 5% w/w.
When used for thermoplastic granulations,a mixture of the powdered constituents with 10–15% w/w PEG 600 is heated to 70–75°C.
The mass becomes pastelike and forms granules if stirred while cooling.
This technique is useful for the preparation of dosage forms such as lozenges when prolonged disintegration is required.
Polyethylene glycols can also be used to enhance the aqueous solubility or dissolution characteristics of poorly soluble compounds by making solid dispersions with an appropriate Polyethylene glycol 600.
Animal studies have also been performed using Polyethylene glycol 600 as solvents for steroids in osmotic pumps.
In film coatings, solid grades of Polyethylene glycol 600 can be used alone for the film-coating of tablets or can be useful as hydrophilic polishing materials.
Solid grades are also widely used as plasticizers in conjunction with film-forming polymers.

The presence of Polyethylene glycol 600 in film coats, especially of liquid grades, tends to increase their water permeability and may reduce protection against low pH in enteric-coating films.
Polyethylene glycol 600 is useful as plasticizers in microencapsulated products to avoid rupture of the coating film when the microcapsules are compressed into tablets.
Polyethylene glycol 600 grades with molecular weights of 6000 and above can be used as lubricants, particularly for soluble tablets.
The lubricant action is not as good as that of magnesium stearate, and stickiness may develop if the material becomes too warm during compression.
An antiadherent effect is also exerted, again subject to the avoidance of overheating.
Polyethylene glycol 600 has been used in the preparation of urethane hydrogels, which are used as controlled-release agents.
Polyethylene glycol 600 has also been used in insulin-loaded microparticles for the oral delivery of insulin;it has been used in inhalation preparations to improve aerosolization;polyethylene glycol nanoparticles have been used to improve the oral bioavailability of cyclosporine;Polyethylene glycol 600 has been used in self-assembled polymeric nanoparticles as a drug carrier;and copolymer networks of polyethylene glycol grafted with poly(methacrylic acid) have been used as bioadhesive controlled drug delivery formulations.
POLYETHYLENE GLYCOL 6000
DESCRIPTION:

Polyethylene Glycol 6000 is a compound used to modify therapeutic proteins and peptides to increase their solubility
Polyethylene glycol 6000 (PEG 6000), with the CAS number 25322-68-3, is a high molecular weight polymer of ethylene oxide commonly used in various scientific and industrial applications due to its unique physicochemical properties.
Polyethylene Glycol 6000, characterized by its long chains and high solubility in water, serves primarily as an inert and non-toxic agent in processes requiring molecular crowding or the alteration of solute mobility and stability.



CAS No.: 25322-68-3
EC Number: 500-038-2
Molecular formula:(C2H4O)nH2O


SYNONYM(S) OF POLYETHYLENE GLYCOL 6000:
Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 6000, PEG


In research, Polyethylene Glycol 6000 has been extensively utilized in the field of protein chemistry, where it acts as a precipitant in the crystallization of proteins.
This utility arises from Polyethylene Glycol 6000′s ability to exclude volume and reduce water activity around macromolecules, thus promoting the necessary interactions for crystal formation without altering the biological activity of the proteins.

Additionally, Polyethylene Glycol 6000 is employed in molecular biology for the preparation of density gradients used in the purification of viruses, nucleic acids, and other macromolecules.
Its role in these applications is pivotal due to its capacity to create a stable environment that supports the separation of biological components based on size and density.
Furthermore, in bioconjugation, Polyethylene Glycol 6000 is used to enhance the solubility and stability of bioactive compounds, thereby facilitating a variety of research methodologies that require modified biomolecules for advanced studies.







APPLICATIONS OF POLYETHYLENE GLYCOL 6000:
Polyethylene Glycol 6000 is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations.
Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more.
Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.



PHYSICOCHEMICAL INFORMATION ABOUT POLYETHYLENE GLYCOL 6000:
Boiling point >200 °C (1013 hPa) Non applicable
Density 1.2 g/cm3 (20 °C)
Flash point 138.6 °C
Ignition temperature 420 °C
Fusion point 58 - 63 °C
pH value 5 - 7 (100 g/l, H₂O, 20 °C)
Vapor pressure Solubility 550 g/l
Color according to Munsell color system not more intensely colored than reference standard NE12
Melting range (lower value) ≥ 59 °C
Melting range (upper value) ≤ 64 °C
Hydroxyl value 15 - 22
Average molecular mass 5000 - 7500
Identity (IR) passes test
CASE
25322-68-3
Molecular formula
(C2H4O)n
Molecular weight (g/mol)
62.07
MDL number
MFCD01779601
InChI Key
LYCAIKOWRPUZTN-UHFFFAOYSA-NShow more
Synonymous
PEG
IUPAC Name
ethane-1,2-diol
SMILES
[H]OCCO
Chemical name or material Poly(ethylene glycol)
Color White
Fitness Powder or glitter
Fusion point 55.0°C to 60.0°C
Linear formula H ( OCH2CH2 ) nOH
Merck Index 15, 7688
Solubility information Solubility in water: 550g/L (20°C). Other solubilities: soluble in thf
Quantity 1 kg
Formula weight 6000
Hydroxyl value 17 to 20mg KOH/g
Conditioning Plastic bottle
Viscosity 220-262 mPa.s (20°C)
Agency
Ph. Eur.
Quality Level
500
vapor pressure
product line
EMPROVE® ESSENTIAL
form
solid
autoignition temp.
420 °C
mol wt
average Mn 6000
technique(s)
API processing | nano-milling: suitable
pH
5-7 (20 °C, 100 g/L in H2O)
mp
58-63 °C
transition temp
flash point 270 °C
solubility
550 g/L
density
1.2 g/cm3 at 20 °C
application(s)
liquid formulation
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement
storage temp.
15-25°C
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
Distributor reference
528877-100GM
Storage area
France and Germany
DGOS nomenclature
LC13AOOO
Type of coloring
White
Certification
RUO
Sterile device
No
CAS number
25322-68-3
CE DIV marking
No
State
Solid
Barcode
Yes
Subjected to dry ice
No
INSERM nomenclature
NA.NA28
Expiry date on delivery date
12 months
Manufacturer reference
528877-100GM
Nomenclature of Mother-of-pearl
NA.28
Brand
MILLIPORE
Specificity
Solubility: water: 200 mg/mL
Subject to regulation
No
Supplier
SIGMA ALDRICH CHEMISTRY
Quantity
N / A
CEA nomenclature
SGP01
Customs Code
34042000
Manufacturer product label
PEG 6000, MOLECULAR BIOLOGY 1PC X 100GM
Manufacturer reference
528877-100GM
CHU nomenclature
18,552
IRSN nomenclature
273
Sold by
100 g
CNRS nomenclature
NA28
Customer error recovery
No



SAFETY INFORMATION ABOUT POLYETHYLENE GLYCOL 6000
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



POLYETHYLENE GLYCOL 8000
DESCRIPTION:

POLYETHYLENE GLYCOL 8000 is a compound used to modify therapeutic proteins and peptides to increase their solubility
POLYETHYLENE GLYCOL 8000 (PEG 8000), with the CAS number 25322-68-3, is a high molecular weight polymer of ethylene oxide commonly used in various scientific and industrial applications due to its unique physicochemical properties.
POLYETHYLENE GLYCOL 8000, characterized by its long chains and high solubility in water, serves primarily as an inert and non-toxic agent in processes requiring molecular crowding or the alteration of solute mobility and stability.



CAS No.: 25322-68-3
EC Number: 500-038-2
Molecular formula:(C2H4O)nH2O


SYNONYM(S) OF POLYETHYLENE GLYCOL 8000:
Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 8000, PEG


In research, POLYETHYLENE GLYCOL 8000 has been extensively utilized in the field of protein chemistry, where it acts as a precipitant in the crystallization of proteins.
This utility arises from POLYETHYLENE GLYCOL 8000′s ability to exclude volume and reduce water activity around macromolecules, thus promoting the necessary interactions for crystal formation without altering the biological activity of the proteins.

Additionally, POLYETHYLENE GLYCOL 8000 is employed in molecular biology for the preparation of density gradients used in the purification of viruses, nucleic acids, and other macromolecules.
Its role in these applications is pivotal due to its capacity to create a stable environment that supports the separation of biological components based on size and density.
Furthermore, in bioconjugation, POLYETHYLENE GLYCOL 8000 is used to enhance the solubility and stability of bioactive compounds, thereby facilitating a variety of research methodologies that require modified biomolecules for advanced studies.







APPLICATIONS OF POLYETHYLENE GLYCOL 8000:
POLYETHYLENE GLYCOL 8000 is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations.
Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more.
Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.



PHYSICOCHEMICAL INFORMATION ABOUT POLYETHYLENE GLYCOL 8000:
Boiling point >200 °C (1013 hPa) Non applicable
Density 1.2 g/cm3 (20 °C)
Flash point 138.6 °C
Ignition temperature 420 °C
Fusion point 58 - 63 °C
pH value 5 - 7 (100 g/l, H₂O, 20 °C)
Vapor pressure <0.1 hPa (20 °C)
Solubility 550 g/l
Color according to Munsell color system not more intensely colored than reference standard NE12
Melting range (lower value) ≥ 59 °C
Melting range (upper value) ≤ 64 °C
Hydroxyl value 15 - 22
Average molecular mass 5000 - 7500
Identity (IR) passes test
CASE
25322-68-3
Molecular formula
(C2H4O)n
Molecular weight (g/mol)
62.07
MDL number
MFCD01779601
InChI Key
LYCAIKOWRPUZTN-UHFFFAOYSA-NShow more
Synonymous
PEG
IUPAC Name
ethane-1,2-diol
SMILES
[H]OCCO
Chemical name or material Poly(ethylene glycol)
Color White
Fitness Powder or glitter
Fusion point 55.0°C to 60.0°C
Linear formula H ( OCH2CH2 ) nOH
Merck Index 15, 7688
Solubility information Solubility in water: 550g/L (20°C). Other solubilities: soluble in thf
Quantity 1 kg
Formula weight 6000
Hydroxyl value 17 to 20mg KOH/g
Conditioning Plastic bottle
Viscosity 220-262 mPa.s (20°C)
Agency
Ph. Eur.
Quality Level
500
vapor pressure
<0.01 hPa ( 20 °C)
product line
EMPROVE® ESSENTIAL
form
solid
autoignition temp.
420 °C
mol wt
average Mn 6000
technique(s)
API processing | nano-milling: suitable
pH
5-7 (20 °C, 100 g/L in H2O)
mp
58-63 °C
transition temp
flash point 270 °C
solubility
550 g/L
density
1.2 g/cm3 at 20 °C
application(s)
liquid formulation
pharmaceutical
semi-solid formulation
solid formulation
solubility enhancement
storage temp.
15-25°C
SMILES string
C(CO)O
InChI
1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key
LYCAIKOWRPUZTN-UHFFFAOYSA-N
Distributor reference
528877-100GM
Storage area
France and Germany
DGOS nomenclature
LC13AOOO
Type of coloring
White
Certification
RUO
Sterile device
No
CAS number
25322-68-3
CE DIV marking
No
State
Solid
Barcode
Yes
Subjected to dry ice
No
INSERM nomenclature
NA.NA28
Expiry date on delivery date
12 months
Manufacturer reference
528877-100GM
Nomenclature of Mother-of-pearl
NA.28
Brand
MILLIPORE
Specificity
Solubility: water: 200 mg/mL
Subject to regulation
No
Supplier
SIGMA ALDRICH CHEMISTRY
Quantity
N / A
CEA nomenclature
SGP01
Customs Code
34042000
Manufacturer product label
PEG 8000, MOLECULAR BIOLOGY 1PC X 100GM
Manufacturer reference
528877-100GM
CHU nomenclature
18,552
IRSN nomenclature
273
Sold by
100 g
CNRS nomenclature
NA28
Customer error recovery
No



SAFETY INFORMATION ABOUT POLYETHYLENE GLYCOL 8000
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





POLYETHYLENE GLYCOL 8000
Polyethylene glycol 8000 is colorless, inert, odorless, and non-volatile. Polyethylene glycol 8000 is biocompatible (it won’t damage tissues or cells), hydrophilic, dissolves readily in water without changing the color odor or taste and is nontoxic.


CAS Number: 25322-68-3
EC Number : 500-038-2
MDL number: MFCD00081839
Linear Formula: H(OCH2CH2)nOH



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Polyethylene glycol 8000, a hydrophilic polymer, is easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups.
On being incorporated into networks by crosslinking, Polyethylene glycol 8000 can have high water content, forming “hydrogels”.


Hydrogel formation can be initiated by either crosslinking Polyethylene glycol 8000 by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends.
Polyethylene glycol 8000 is a suitable compound with a wide scope in biological applications since it does not elicit any immune responses.


Polyethylene glycol 8000 has been shown to modify therapeutic proteins and peptides for enhanced solubility.
Additionally, photopolymerized Polyethylene glycol 8000 hydrogels have emerging applications in the fabrication of bioactive and immune-isolating barriers for encapsulation of cells.
Polyethylene glycol 8000 has low toxicity with systemic absorption less than 0.5%.


High-molecular weight Polyethylene glycol 8000 provides enhanced solvency, lubricity, hygroscopicity and other important functional properties in a wide range of formulations.
Polyethylene glycol 8000 is a white or almost white solid with a waxy or paraffin-like appearance.


Polyethylene glycol 8000 is very soluble in water and in methylene chloride, very slightly soluble in alcohol, practically_x000D_ insoluble in fatty oils and in mineral oils.
The kinetics of the ligation in the cloning of DNA-fragments into bacteriophage M13-vectors can be improved by the inclusion of 5% Polyethylene glycol 8000.


Polyethylene glycol 8000 has a molecular weight of 8000 and is sold in its granular form.
Polyethylene glycol 8000 can be hydrated to be a clear, colorless, viscous liquid.
This is the highest molecular weight sold and will provide the highest viscosity.


Polyethylene glycol 8000 is colorless, inert, odorless, and non-volatile. Polyethylene glycol 8000 is biocompatible (it won’t damage tissues or cells), hydrophilic, dissolves readily in water without changing the color odor or taste and is nontoxic.
Polyethylene glycol 8000 is a high-quality reagent that has been certified by the National Formulary (NF), which makes it suitable for biological substances, dosage forms, compounded preparations, medical devices, and dietary supplements.


Polyethylene glycol 8000 is a polyethylene glycol having white to off white color and available in solid flakes or powder form.
High molecular weight Polyethylene glycol 8000 that provides enhanced solvency, lubricity, hygroscopicity and other important functional properties in a wide range of formulations.


Polyethylene glycol 8000 is a hard, waxy solid having the appearance of thin, irregularly shaped shards.
Chemically equivalent to Polyethylene glycol 8000's spherical granular counterpart, being produced from the same molten material.
Polyethylene glycol 8000 used as a base in the formulation of soap sticks.


Polyethylene glycol 8000 has low glycol content and higher crystalinity.
Polyethylene glycol 8000's high molecular weight mainly prompts its use in pharmaceutical formulations as solvent for oral, topical and parenteral preparations.


The high molecular weight Polyethylene glycol 8000 is soluble in water and organic solvents such as alcohols.
Polyethylene glycol 8000 is a water-soluble linear polymer formed by the addition reaction of ethylene oxide.
Polyethylene glycol 8000 is PEG-180-based mold release agent and plasticizer.


Polyethylene glycol 8000 possesses lubricity and humectant properties.
Polyethylene glycol 8000 can blend with other PEG molecular weights to achieve the desired viscosity properties.
Polyethylene glycol 8000 is quite stable and does not support microbial growth, even in aqueous solutions.


Polyethylene glycol 8000 is a white crystals for molecular biology applications such as precipitation of DNA, nucleic acids, hybridization and fusion of mammalian cells.
Melting Point of Polyethylene glycol 8000 is 55°-60°C


Polyethylene glycol 8000 is a white to off-white waxy material in flakes, granules, and powdered form.
Polyethylene glycol 8000 has low glycol content and higher crystallinity.
Polyethylene glycol 8000 contains the added stabilizer, BHT, at a nominal concentration of 100 PPM.


High molecular weight Polyethylene glycol 8000 that provides enhanced solvency, lubricity, hygroscopicity and other important functional properties in a wide range of formulations.
Polyethylene glycol 8000 is a hard, waxy solid having the appearance of thin, irregularly shaped shards.


Polyethylene glycol 8000 is a white or almost white solid with a waxy or paraffin-like appearance.
Polyethylene glycol 8000 is very soluble in water and in methylene chloride, very slightly soluble in alcohol, practically insoluble in fatty oils and in mineral oils.


Owing to the lower surface area as compared to the granular form, the flaked grade exhibits longer relative dissolution times in water-based applications.
Polyethylene glycol 8000 will not support microbial growth, even in aqueous solutions
Versatile, water-miscible vehicle used as solvent and solubilising agent for active substances and excipients in liquid and semi-sollid preapration.



USES and APPLICATIONS of POLYETHYLENE GLYCOL 8000:
Polyethylene glycol 8000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene glycol 8000 is a compound used to modify therapeutic proteins and peptides to increase their solubility.
Polyethylene glycol 8000 is often utilized in mass spectrometry experiments and as a polar stationary phase for Gas Chromatorgraphy.


Polyethylene glycol 8000 is also used to preserve objects that have been retrieved from the ocean.
Polyethylene glycol 8000 is used high quality polysorbates available for use in pharmaceutical, cosmetic and feed industry.
Polyethylene glycol 8000 has been used in the precipitation of proteins, as a fusing agent in enhancing the effect of macrophages on hybridoma, in the separation and purification of biomolecules and in induction of cell hybridization.


In fabricating elastomers, Polyethylene glycol 8000 functions as a lubricant and mold releasing agent.
In pharmaceuticals, Polyethylene glycol 8000 powder can function as a tablet and capsule lubricant.
Polyethylene glycol 8000 is used as a lubricant to coat aqueous and non-aqueous surfaces


Polyethylene glycol 8000 is used as antistatic agent, lubricant, etc. in the textile industry.
Polyethylene glycol 8000 is used in Adhesives, Ceramic BinderCeramic Binder, Chemical Intermediates, Detergents and Household Cleaners, Dye Carrier, Lubricants, Mining, Mold Release Agent, Plasticizer, and Wood Treating.


Polyethylene glycol 8000 is used as a plasticizer in tablet coating providing hardness as well as water solubility and lubricity.
Polyethylene glycol 8000 is used as a chemical intermediate in the synthesis of pharmaceuticals
Especially for the cloning with 'blunt-ended' DNA, the concentration of 'blunt'-DNA-ends plays a crucial role for the successful cloning.


Polyethylene glycol 8000 is used as a matrix in pharmaceutical and cosmetic industrial production to adjust viscosity and melting point.
Polyethylene glycol 8000 is used as lubricant and coolant in rubber and metal processing industries.
Substances, that increase the so-called 'macromolecular crowding' and condense DNA molecules into aggregates, concentrate the DNA and increase the possibility, that DNA ends will meet and thereby improve the cloning result.


So, the DNA and enzyme concentration can be reduced.
Polyethylene glycol 8000 is used as dispersant and emulsifier in the industrial production of pesticides and pigments.
Polyethylene glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility.


Besides, such substances reduce the intramolecular ligation (religation).
For 'blunt end' cloning the recommended Polyethylene glycol 8000 concentration is 15%.
Stock solutions of Polyethylene glycol 8000 are prepared with deionized water and stored at -20°C in small aliquots.


Polyethylene glycol 8000 is used as lubricant and coolant in rubber and metal processing industry, dispersant and emulsifier in pesticide and pigment industry production.
Polyethylene glycol 8000 is used as antistatic agent and lubricant in textile industry.


Polyethylene glycol 8000, a hydrophilic polymer, is used in the modification of therapeutic proteins and peptides to enhance its solubility.
Polyethylene glycol 8000 is used as matrix in pharmaceutical and cosmetic industry to regulate viscosity and melting point.
Polyethylene glycol 8000 maintains wet-tack strength and is used in pressure-sensitive and thermoplastic adhesives.


Polyethylene glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility.
Polyethylene glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
In gas chromatography, Polyethylene glycol 8000 is used as a polar stationary phase.


Polyethylene glycol 8000 is used as mold release agent and lubricant in fabricating elastomers.
As a dispersant, Polyethylene glycol 8000 is used in toothpastes.
Polyethylene glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.


In pharmaceutical industry, Polyethylene glycol 8000 is used as tablet and capsule lubricant.
Polyethylene glycol 8000meets the requirements for use under food additive regulations for indirect use as components of articles intended for use in contact with food.


Polyethylene glycol 8000 is suitable as a medium for the fusion of mammalian cells.
Polyethylene glycol 8000 is also used to precipitate bacteriophage from lysed cell supernatants.
Polyethylene glycol 8000 is used Chromatography (GC & HPLC), Decontamination & cleaning, Karl Fischer titration, Kjeldahl analysis, Microbiology & cell culture, Proteinbiochemistry, Spectroscopy & MS, Titration


Polyethylene glycol 8000 is used as solvent, antifreeze and raw material for synthetic polyester.
Polyethylene glycol 8000 is used as mold release agent and lubricant in fabricating elastomers.
As a dispersant, Polyethylene glycol 8000 is used in toothpastes.


Polyethylene glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.
Polyethylene glycol 8000, a high polymer of ethylene glycol, is a phase transfer catalyst and is also used in cell fusion
Polyethylene glycol 8000 is used in the precipitation of phage, isolation of plasmid DNA and the enhancement of blunt-ended ligation reactions.


Polyethylene glycol 8000 is used Fragrance carrier, Ceramics, Automotive sprays, Household cleaners, Dye carrier, Lubricants, Mining, Mold release agent, Plasticizer, and Wood treating.
Polyethylene glycol 8000 is used in the modification of therapeutic proteins and peptides to enhance its solubility.


Polyethylene glycol 8000 is used pharmaceutical products, personal care products, automotive products, household products, packaging products, petroleum chemicals, plastics, inks, coatings, adhesives, chemical interme, Industrial chemical intermediary, pharmaceutical products, personal care products, automotive products, household products, packaging products, petroleum chemicals, plastics, inks, coatings, adhesives, chemical intermediates, rubber processing, lubricants, metalworking fluids, mold releas, Surfactant.


Polyethylene glycol 8000 is used as mold release agent and lubricant in fabricating elastomers.
As a dispersant, Polyethylene glycol 8000 is used in toothpastes.
Polyethylene glycol 8000 finds application in blood banking as a potentiator, which is used to detect antigens and antibodies.


In pharmaceutical industry, Polyethylene glycol 8000 is used as tablet and capsule lubricant.
Polyethylene glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
In gas chromatography, Polyethylene glycol 8000 is used as a polar stationary phase.


Polyethylene glycol 8000 acts as a lubricant, coating the surfaces in aqueous and non-aqueous environments.
Polyethylene glycol 8000 is a partial list of applications include pharmaceutical products, personal care products, automotive products, household products, packaging products, petroleum chemicals, plastics, inks, coatings, adhesives, chemical intermediates, rubber processing, lubri.


Polyethylene glycol 8000 is used Fragrance carrier, Ceramics, Automotive sprays, Household cleaners, Dye carrier, Lubricants, Mining, Mold release agent, Plasticizer, Wood treating, and Powdered detergents.
Polyethylene glycol 8000 is used as an inactive ingredient in the pharmaceutical industry as a solvent, plasticizer, surfactant, ointments and suppository base, and tablet and capsule lubricant.


Polyethylene glycol 8000 is also used as a fusogen (induces cell hybridization) to obtain hybridomas for monoclonal antibody production.
Polyethylene glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
In gas chromatography, Polyethylene glycol 8000 is used as a polar stationary phase.


In pharmaceutical industry, Polyethylene glycol 8000 is used as tablet and capsule lubricant.
Polyethylene glycol 8000 is vastly used for the isolation of plasmid DNA, precipitation of phage, modification of therapeutic proteins and peptides to enhance its solubility.


Polyethylene glycol 8000 is also used in the fabrication of bioactive and immuno isolating barriers for encapsulation of cells.
Polyethylene glycol 8000 is suitable as a medium for the fusion of mammalian cells.
Polyethylene glycol 8000 is also used to precipitate bacteriophage from lysed cell supernatants.


Key Applications of Polyethylene glycol 8000: Precipitation of proteins | Separation and purification of biomolecules.
Polyethylene glycol 8000 is for research or further manufacturing use only, not for food or drug use.
Crystallization grade Polyethylene glycol 8000 for formulating screens or for optimization.


Polyethylene glycol 8000 is used Pharmaceuticals - excipients, Food contact, Cosmetic, Personal care, and Chemical intermediates.
Polyethylene glycol 8000 can be paired with surfactants (for example Kolliphor RH 40) to promote solubilization of poorly water-soluble APIs
Polyethylene glycol 8000 can be used for crystallization ihibition with polymers (for example Kollidon 12 PF)
Polyethylene glycol 8000 can also be used as a chemical intermediate in drug formulation



BENEFITS OF POLYETHYLENE GLYCOL 8000:
*Polyethylene glycol 8000 will not support microbial growth, even in aqueous solutions
*Versatile, water-miscible vehicle used as solvent and solubilizing agent for active substances and excipients in liquid and semisolid preparation
*Polyethylene glycol 8000 can be paired with surfactants (for example Kolliphor RH 40) to promote solubilization of poorly water-soluble APIs
*Polyethylene glycol 8000 can be used for crystallization inhibition with polymers (for example Kollidon 12 PF)
*Polyethylene glycol 8000 can also be used as a chemical intermediate in drug formulation
*Anti-caking properties in powder detergents
*Acts as a carrier for starch wetting for after wash automotive sprays
*Fragance carrier in scent booster beads
*Binder and plasticizer for green-body formation in ceramics



FUNCTIONALITIES OF POLYETHYLENE GLYCOL 8000:
*Plasticizers,
*Viscosity modifiers,
*Solubilizers



BENEFITS OF POLYETHYLENE GLYCOL 8000:
*Binder and plasticizer for green-body formation
*Anti-caking properties, and acts as a carrier for starch
*Water solubility
*Nonvolatility
*Inertness
*Lubricity



FUNCTIONS OF POLYETHYLENE GLYCOL 8000:
*Binder,
*Consistency factors & viscosity enhancement,
*Plasticization,
*Solvent,
*Structurants & matrix builders



FEATURES OF POLYETHYLENE GLYCOL 8000:
*Sterile filtered solution
*Formulated in Type 1+ ultrapure water: 18.2 megaohm-cm resistivity at 25°C, < 5 ppb Total Organic Carbon, bacteria free (


BENEFITS OF POLYETHYLENE GLYCOL 8000:
*Proven performance in a variety of excipient formulations
*Compliance with USP/NF and Ph. Eur. monographs
*Solubilize / disperse wide variety of components
*Tune formulation to achieve desired form (solid, liquid with certain viscosities and melt-freeze points)
*Attract and retain moisture—ideal for ointments and lotions



INDUSTRIES OF POLYETHYLENE GLYCOL 8000:
*Pharmaceuticals especially the production of tablet binding and coating
*Research and pharmaceuticals as a chemical intermediate
Industrial lubricant applications



MARKET OF POLYETHYLENE GLYCOL 8000:
*Chemical Synthesis,
*Cosmetics & Personal Care,
*Household & Industrial Cleaning,
*Meat,
*Baking, and Processed Food,
*Pharmaceutical,
*Nutritional & Healthcare



PHYSICAL and CHEMICAL PROPERTIES of POLYETHYLENE GLYCOL 8000:
Molecular Weight: 7000-9000
Appearance Form: solid
Color: light yellow
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: 57,5 °C
Initial boiling point and boiling range: 205,7 °C at 977,6 hPa
Flash point: 138,6 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 0,01 hPa at 20 °C
Vapor density: No data available
Density: 1,116 g/cm3 at 20 °C at 975,5 hPa
Relative density: No data available

Water solubility: 256,084 g/l at 25 °C
Partition coefficient: n-octanol/water
log Pow: -0,698 at 30 °C - Bioaccumulation is not expected.
Autoignition temperature: 360 °C
Decomposition temperature: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Physical Form: Solid
Average Number of Repeating Oxyethylene Units: 181
Range of Average Molecular Weight: 7000 – 9000

Range of Average Hydroxyl Number, mg KOH/g: 12 – 16
Density, g/cm3 at 70°C: 1.07
Melting or Freezing Range, °C: 55 – 62
Solubility in Water at 20°C, % by weight: 63
Viscosity at 100°C: cSt 500 - 900
Heat of Fusion: Cal/g 41
CAS NO: 25322-68-3
MOLECULAR FORMULA: HO(C2H4O)nH
PHYSICAL DESCRIPTION: Solid
PRODUCT CODE: A2204
PRODUCT NAME: Polyethylene glycol 8000 BioChemica
SPECIFICATIONS:
Average M: 7000 - 9000
Solubility (5 %; H2O): clear, colorless
pH (5 %; H2O; 20°C): 5.5 - 7.0

Heavy metals: max. 0.005%
WGK: 1
STORAGE: RT
EINECS: 500-038-2
Molar mass (M): 7300-9000 g/mol
Density (D): 1,2 g/cm³
Flash point (flp): 270 °C
Melting point (mp): 60 °C
WGK: 1
CAS No.: 25322-68-3
EG-Nr.: 500-038-2
CAS: 25322-68-3
Molecular Formula: (C2H4O)n
Molecular Weight (g/mol): 62.07
MDL Number: MFCD01779601

InChI Key: LYCAIKOWRPUZTN-UHFFFAOYSA-N
Synonym: PEG 8000
IUPAC Name: ethane-1,2-diol
SMILES: [H]OCCO
Color: White
pH: 5 to 7
Physical Form: Powder
Melting Point: 55°C to 63°C
Merck Index: 14,7568
Solubility Information: Soluble in water and aromatic hydrocarbons.
Slightly soluble in aliphatic hydrocarbons and organic solvents.
Odor: Odorless
Chemical Name or Material: Polyethylene glycol 8,000
CAS: 25322-68-3
Molecular formula: H(OCH2CH2)nOH

Molecular weight: 7000 - 9000
Appearance: White/colorless powder or flakes
Solubility: Clear solution at 5% in water at 25°C
Melting point: 61 - 64 °C
pH (5%, H2O): 5.5 - 7.0
Water: < 0.5 %
UV data: 260 nm: < 0.099
280 nm: < 0.03
Peroxides (H2O2): < 0.001 %
Chloride: < 50 ppm
Copper: < 5 ppm
Iron: < 5 ppm
Storage: Room Temperature. Protect from moisture.
Stability: Stable at least 2 years at R.T
CAS: 25322-68-3

Molecular Formula: (C2H4O)n
Molecular Weight (g/mol): 62.07
MDL Number: MFCD01779601
InChI Key: LYCAIKOWRPUZTN-UHFFFAOYSA-N
Synonym: PEG 8000, Polyethylene Oxide, Carbowax™
IUPAC Name: ethane-1,2-diol
SMILES: [H]OCCO
Appearance :Powder
Physical State :Solid
Solubility : Soluble in water (500 g/l at 20° C), aromatic hydrocarbons (very soluble),
aliphatic hydrocarbons (slightly soluble), and organic solvents.
Storage :Store at room temperature
Melting Point :62.2° C
Boiling Point :250° C at 1013 hPa
Density :1.21 g/cm3 at 20° C



FIRST AID MEASURES of POLYETHYLENE GLYCOL 8000:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact: rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POLYETHYLENE GLYCOL 8000:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Take up dry.
Clean up affected area.



FIRE FIGHTING MEASURES of POLYETHYLENE GLYCOL 8000:
-Extinguishing media:
*Suitable extinguishing media:
Water Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Special hazards arising from the substance or mixture:
Nature of decomposition products not known.
-Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYETHYLENE GLYCOL 8000:
-Control parameters:
Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of POLYETHYLENE GLYCOL 8000:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
Stored at room temperature.
But close the lid of the bottle tightly.
The product has a shelf life of at least 2 years.



STABILITY and REACTIVITY of POLYETHYLENE GLYCOL 8000:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions: No data available

POLYETHYLENE GLYCOL,TECHNICAL GRADE
PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); CAS NO:25322-68-3
Polyethylene Glycols (PEG)
PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); CAS NO:25322-68-3
Polyethylene Terephthalate
Polyethylene Terephthalate; poly(ethylene terephthalate); poly(oxyethyleneoxyterephthaloyl) cas no: 25038-59-9
POLYETHYLENE WAX - PE WAX
Polyethylene Wax - PE Wax can be used as a disperant, slip agent, resin additive, and mold release agent.
As an oxidised product, Polyethylene Wax - PE Wax is authorized in the EU as E number reference E914 only for the surface treatment of some fruits.
There are a variety of methods for producing Polyethylene Wax - PE Wax.

CAS: 9002-88-4
MF: (C2H4)n
MW: 28.05316
EINECS: 618-339-3

Synonyms
pad522;pe512;pe617;pen100;pep211;pes100;pes200;petrothene

Polyethylene Wax - PE Wax can be made by direct polymerization of ethylene under special conditions that control molecular weight and chain branching of the final polymer.
Another method involves thermal and/or mechanical decomposition of high molecular weight polyethylene resin to create lower molecular weight fractions.
A third method involves separation of the low molecular weight fraction from a production stream of high molecular weight polymer.
These last two methods produce very low molecular weight fractions that should be removed to avoid a product with low flash point that can result in flammability, migration, equipment build up, fouling and other safety and processing issues.
Volatiles in these un refined waxes can also account for significant yield loss during processing.
Polyethylene Wax - PE Wax may be used as lubricant additive to the PVC pipes.
Polyethylene Wax - PE Wax is a flexible waxy translucentpolyalkene thermoplastic made in avariety of ways producing a polymerof varying characteristics.

In the ICIprocess, ethene containing a trace of oxygen is subjected to a pressure inexcess of 1500 atmospheres and atemperature of 200°C.
Low-densitypolyethene (r.d. 0.92) has a formulaweight between 50 000 and 300 000,softening at a temperature around110°C, while the high-density polythene(r.d. 0.945–0.96) has a formulaweight up to 3 000 000, softeningaround 130°C.
The low-density polymeris less crystalline, being more atactic.
Polyethene is used as aninsulator; Polyethylene Wax - PE Wax is acid resistant and iseasily moulded and blown.
Polyethylene Wax - PE Wax is a water-repellent, white, tough, leathery, thermoplastic resin very similar in appearance to paraffin wax.
Properties vary from a viscous liquid at low molecular weights to a hard waxlike substance at high molecular weights.
Polyethylene Wax - PE Wax is used as a coating for glass bottles and fiberglass fabrics (special treatments for glass are required to obtain good adhesion between polyethylene and glass) and is also used as an injection-molding material for ceramics.

In the polymerization process, the double bond connecting the carbon atoms is broken.
Under the right conditions, these bonds reform with other ethylene molecules to form long molecular chains.
Ethylene copolymers, EVA, and EEA are made by the polymerization of ethylene units with randomly distributed comonomer groups, such as vinyl acetate (VA) and ethyl acrylate (EA).
Polyethylene Wax - PE Wax, also known as PE Wax, is an ultra low molecular weight polyethylene consisting of ethylene monomer chains.
Polyethylene Wax - PE Wax has a large variety of uses and applications.
Polyethylene Wax - PE Wax is available from on-purpose production and as a byproduct of polyethylene production.
Polyethylene Wax - PE Wax is available in both HDPE and LDPE forms.
As there are many grades and types available, please inquire so that one of our knowledgeable representatives can assist you in locating the correct grade that matches your requirements.

Polyethylene Wax - PE Wax stands for Polyethylene Wax.
Polyethylene Wax - PE Wax is a synthetic wax made from polyethylene, a polymer made from ethylene monomers.
Polyethylene Wax - PE Wax is commonly used as a processing aid, lubricant, and release agent in various industries.
Polyethylene Wax - PE Wax has a low molecular weight and is characterized by its hardness, toughness, and excellent low-temperature properties.
Polyethylene Wax - PE Wax is also highly resistant to water and chemicals, making it suitable for use in a wide range of applications, including coatings, adhesives, inks, plastics, and rubber.
Polyethylene Wax - PE Wax is available in various forms such as powder, flake, or granules, and its properties can be adjusted by varying its molecular weight and degree of branching.
Polyethylene Wax - PE Wax's versatility and wide range of applications make PE wax a popular choice in many industries.

Polyethylene Wax - PE Wax Chemical Properties
Melting point: 92 °C
Boiling point: 48-110 °C(Press: 9 Torr)
Density: 0.962 g/mL at 25 °C
Fp: 270 °C
Storage temp.: -20°C
Form: powder
Color: White
Specific Gravity: 0.95
Water Solubility: Soluble in acetone and benzene. Insoluble in water.
Merck: 14,7567
Dielectric constant: 2.2(Ambient)
Stability: Stable, but breaks down slowly in uv light or sunlight.
Incompatible with halogens, strong oxidizing agents, benzene, petroleum ether, aromatic and chlorinated hydrocarbons, lubricating oils.
IARC: 3 (Vol. 19, Sup 7) 1987
NIST Chemistry Reference: Polyethylene Wax - PE Wax(9002-88-4)
EPA Substance Registry System: Polyethylene Wax - PE Wax (9002-88-4)

Chemical and physical properties are markedly affected by increasing density, which is affected by the shape and spacing of the molecular chain.
Low-density materials have highly branched and widely spaced chains, whereas high-density materials have comparatively straight and closely aligned chains.
Low-density polyethylene (0.926–0.9409 g/cm3) is soluble in organic solvents at temperatures higher than 200°F.
Polyethylene Wax - PE Wax is insoluble at room temperature.
High-density polyethylene (0.041–0.965 g/cm3) is hydrophobic, permeable to gas, and has high electrical resistivity.
Low molecular weight polyethylenes have excellent electrical resistance and resistance to water and to most chemicals.

Medium molecular weight polymers are waxes miscible with paraffin wax, and polyethylene polymers whose molecular weights are higher than 10,000 are the familiar tough and strong resins that are flexible or stiff.
By varying the catalyst and methods of polymerization, properties such as density, crystallinity, molecular weight, and polydispersity can be regulated over wide ranges.
Polymers with densities ranging from approximately 0.910 to 0.925 g/cm3 are low-density polyethylenes; those with densities ranging from 0.926 to 0.940 g/cm3 are medium-density polyethylenes; and those with densities ranging from 0.941 to 0.965 g/cm3 and higher are high-density polyethylenes.

As the crystallinity or density increases, Polyethylene Wax - PE Wax generally become stiffer and stronger and have a high softening temperature and high resistance to penetration by liquids and gases.
At the same time, they lose some of their resistance to tear and environmental stress cracking.
High-density PE (HDPE) is a chemically pure, porous plastic implant material that can perform supportive functions.
The material has good tissue biocompatibility and permits ingrowth of connective tissue with related vascularization.
Polyethylene Wax - PE Wax is being used more frequently in nasal surgery.
Polyethylene can be cross-linked by irradiation (electron beam, gamma, or X radiation) or by free radical catalysts such as peroxides.

PE WAX PHYSICAL PROPERTIES
Polyethylene Wax - PE Wax, also known as polyethylene wax.
Polyethylene Wax - PE Wax is used in a variety of industries, including plastics, coatings, adhesives, and printing inks, due to its unique physical properties.
Some of the physical properties of PE wax include:
Molecular Weight: Polyethylene Wax - PE Wax has a relatively low molecular weight compared to other types of waxes.
This makes Polyethylene Wax - PE Wax a softer wax that has a lower melting point.
Melting Point: Polyethylene Wax - PE Wax typically has a melting point ranging from 105°C to 135°C, depending on the specific grade of the wax.
Density: Polyethylene Wax - PE Wax has a density ranging from 0.91 to 0.94 g/cm3, making it a relatively lightweight wax.

Hardness: Polyethylene Wax - PE Wax is a relatively soft wax, with a hardness ranging from 2 to 4 on the Mohs scale.
Slipperiness: Polyethylene Wax - PE Wax has a high degree of slipperiness, making it an excellent lubricant for plastics and other materials.
Chemical Resistance: Polyethylene Wax - PE Wax is highly resistant to chemicals, making it an ideal choice for coatings and other applications where chemical resistance is important.
Water Repellency: Polyethylene Wax - PE Wax is hydrophobic, meaning it repels water.
This makes Polyethylene Wax - PE Wax an excellent choice for coatings and other applications where water repellency is important.
Overall, the physical properties of Polyethylene Wax - PE Wax make it a versatile material with a wide range of applications across many different industries.

Uses
Polyethylene Wax - PE Wax is a thermoplastic polymer consisting of long hydrocarbon chains.
Polyethylene Wax - PE Wax is used in a number of applications including flexible film packaging produced by the blown film process.
Polyethylene Wax - PE Wax is used to regulate viscosity, suspension properties, and general stability in cosmetic formulations.
Typical applications included specialty injection molded parts, in these fields Polyethylene has a wide range of uses:
Injection and blow molded toys, housewares and lids.
Injection molded car seats, mower parts and pails.
Injection molded, thin-walled containers and housewares.
Hot melt coating for paper, additive in cast moldings, candles, oil-based inks and hot melt adhesives.

Additive to unsaturated polyesters, epoxides and other polymers to impart the unique properties of UHMWPE.
Used in industrial parts, coatings and wear surfaces at 10-40 wt. %.
Film applications having good drawdown and toughness.
Mold release additive, lubricant in rubber processing, extrusion and calendering aid for PVC and dispersing aid for color concentrates.
Bearings, gears, bushings and other moving parts.
Laboratory tubing; in making prostheses; electrical insulation; packaging materials; kitchenware; tank and pipe linings; paper coatings; textile stiffeners.
Polyethylene Wax - PE Wax is used to regulate viscosity, suspension properties, and general stability in cosmetic formulations.
Polyethylene Wax - PE Wax is derived from petroleum gas or dehydration of alcohol.

Polyethylene Wax - PE Wax have very unique polymer properties that make them useful in many applications.
The major functions of Polyethylene Wax - PE Wax in many formulations are to either provide lubrication and/or provide physical modification of a formula by changing viscosity and / or melt point.

Polyethylene Wax - PE Wax increase inorganic and organic pigment dispersion in
matrix polymer during masterbach processing.
Also, Polyethylene Wax - PE Wax helps granule produce by decrease softening point of system.
Polyethylene Wax - PE Wax is very good external lubricant for PVC.
When Polyethylene Wax - PE Wax use in PVC application, final produce face has been shine.
Polyethylene Wax - PE Wax using decrease the friction so increase the extrusion capacity.
Polyethylene Wax - PE Wax using doesn’t change the product color because PE wax has got good oxidation resistance.
Polyethylene Wax - PE Wax doesn’t bad effect product’s heat and light stability because pe wax doesn’t include catalizors remnant.
Polyethylene Wax - PE Wax increase last product’s light stability.
Polyethylene Wax - PE Wax hasn’t got toxic materials so PE wax can be use food packaging applications.
Polyethylene Wax - PE Wax use hot melt application.

Industrial uses
Polyethylene Wax - PE Wax include lowdensity polyethylenes (LDPE), linear low-density polyethylenes (LLDPE), high-density polyethylenes (HDPE), and ethylene copolymers, such as ethylene-vinyl acetate (EVA) and ethylene- ethyl acrylate (EEA), and ultrahighmolecular- weight polyethylenes (UHMWPE).
The basic properties of polyethylenes can be modified with a broad range of fillers, reinforcements, and chemical modifiers, such as thermal stabilizers, colorants, flame retardants, and blowing agents.
Major application areas for polyethylenes are packaging, industrial containers, automotive, materials handling, consumer products, medical products, wire and cable insulation, furniture, housewares, toys, and novelties.
Polyethylene Wax - PE Wax, the first of the polyethylenes to be developed, has good toughness, flexibility, low-temperature impact resistance, clarity in film form, and relatively low heat resistance.
Like the higher-density grades, Polyethylene Wax - PE Wax has good resistance to chemical attack.
One of the fastest-growing plastics is linear Polyethylene Wax - PE Wax, used mainly in film applications but also suitable for injection, rotational, and blow molding.

Properties of Polyethylene Wax - PE Wax are different from those of conventional LDPE and HDPE in that impact, tear, and heat-seal strengths and environmental stress-crack resistance of LLDPE are significantly higher.
Major uses at present are grocery bags, industrial trash bags, liners, and heavy-duty shipping bags for such products as plastic resin pellets.
Rigidity and tensile strength of the HDPE resins are considerably higher than those properties in the low- and medium-density materials.
Impact strength is slightly lower, as is to be expected in a stiffer material, but values are high, especially at low temperatures, compared with those of many other thermoplastics.
HDPE resins are available with broad, intermediate, and narrow molecular-weight distribution, which provides a selection to meet specific performance requirements.

As with the other polyethylene grades, very-high-molecular- weight copolymers of HDPE resins are available with improved resistance to stress cracking.
Applications of HDPE range from film products to large, blow-molded industrial containers.
The largest market area is in blowmolded containers for packaging milk, fruit juices, water, detergents, and household and industrial liquid products.
Other major uses include high-quality, injection-molded housewares, industrial pails, food containers, and tote boxes; extruded water and gas-distribution pipe, and wire insulation; and structural-foam housings.
HDPE resins are also used to rotationally mold large, complex-shaped products such as fuel tanks, trash containers, dump carts, pallets, agricultural tanks, highway barriers, and water and waste tanks for recreational vehicles.

Production Methods
Polyethylene Wax - PE Wax is produced by a low-pressure solution or gasphase process that is initiated by a variety of transition metal catalysts.
The most common catalysts are Ziegler titanium compounds with aluminum alkyls and Phillips chromium oxide-based catalysts.
The gas-phase and slurry processes are used to produce high molecular weight, high-density (HMW-HDPE) products.
The highest density linear PEs can be made from an α-olefin comonomer, typically octene for the solution process and butene or hexene for the gas-phase process.
Polyethylene Wax - PE Wax does not have long-chain branches and is therefore more crystalline.

The short-chain branches found in linear Polyethylene Wax - PE Wax serve as tie molecules, which give the higher α -olefin copolymers improved puncture and tear properties.
Included in the linear Polyethylene Wax - PE Wax family are ultra-low-density PE (ULDPE), LLDPE, and HDPE.
HDPE’s main use is in blow-molded products such as milk bottles, packaging containers, drums, car fuel tanks, toys, and houseware.
Film and sheet are widely used in wrappings, refuse sacks, carrier bags, and industrial liners.

Injection molding products include crates, pallets, packaging containers, houseware, and toys.
Extrusion grades are used in pipes, conduit, wire coating, and cable insulation.
Polyethylene Wax - PE Wax is a thermoplastic that in many applications replaces its predecessor, low-density polyethylene (LDPE), or is used in blends with LDPE.
In particular, LDPE’s shortchain branching gives it higher tensile strength, puncture, and anti-tear properties, making Polyethylene Wax - PE Wax especially suitable for film applications.
There are a variety of methods for producing Polyethylene wax.
Polyethylene Wax - PE Wax can be made by direct polymerization of ethylene under special conditions that control molecular weight.
Another method involves breaking down high molecular weight polyethylene into lower molecular weight fractions.
A third method involves separation of the low molecular weight fraction from high molecular weight polymer.
Polyethylene Wax Types
Polyethylene Waxes; HDPE; LDPE; high density polyethylene wax; low density polyethylene wax;
Polyéthylèneglycol 200 à 8000 (PEG)
SYNONYMS Polyaziridine;Polyethenimide;POLYETHYLENE IMINE;Polyethyleneimine;Polyethylenimine;Polymin 6;Polymin FL;Polymin G 100;Polymin G 15M;Polymin G 20 CAS NO:9002-98-6
POLYETHYLENEIMINE
POLYGLUCURONIC ACID, N° CAS : 36655-86-4. Nom INCI : POLYGLUCURONIC ACID. Nom chimique : D-Glucuronic Acid Homopolymer. Ses fonctions (INCI). Agent d'entretien de la peau : Maintient la peau en bon état
POLYETHYLENEIMINE
DESCRIPTION:
Polyethylenimine (PEI) or polyaziridine is a polymer with repeating units composed of the amine group and two carbon aliphatic CH2CH2 spacers.
Linear polyethyleneimines contain all secondary amines, in contrast to branched PEIs which contain primary, secondary and tertiary amino groups.
Totally branched, dendrimeric forms were also reported.[1]
Polyethylenimine is produced on an industrial scale and finds many applications usually derived from its polycationic character.[2]

CAS Number : 9002-98-6
IUPAC name: Poly(iminoethylene)
Linear Formula:H(NHCH2CH2)nNH2


SYNONYM(S) OF POLYETHYLENIMINE:
aziridine, homopolymer, PEI


PROPERTIES OF POLYETHYLENIMINE:
The linear PEI is a semi-crystalline solid at room temperature while branched PEI is a fully amorphous polymer existing as a liquid at all molecular weights.
Linear polyethyleneimine is soluble in hot water, at low pH, in methanol, ethanol, or chloroform.
Polyethylenimine is insoluble in cold water, benzene, ethyl ether, and acetone.
Linear polyethyleneimine has a melting point of around 67 °C.[3]


Both linear and branched polyethyleneimine can be stored at room temperature.
Linear polyethyleneimine is able to form cryogels upon freezing and subsequent thawing of its aqueous solutions.[3]


SYNTHESIS OF POLYETHYLENIMINE:
Branched Polyethylenimine can be synthesized by the ring opening polymerization of aziridine
Depending on the reaction conditions different degree of branching can be achieved.
Linear Polyethylenimine is available by post-modification of other polymers like poly(2-oxazolines) [5] or N-substituted polyaziridines.


Linear Polyethylenimine was synthesised by the hydrolysis of poly(2-ethyl-2-oxazoline)[7] and sold as jetPEI.[8]
The current generation in-vivo-jetPEI uses bespoke poly(2-ethyl-2-oxazoline) polymers as precursors.[9]


APPLICATIONS OF POLYETHYLENIMINE:
Polyethyleneimine finds many applications in products like: detergents, adhesives, water treatment agents and cosmetics.[10]
Owing to its ability to modify the surface of cellulose fibres, Polyethylenimine is employed as a wet-strength agent in the paper-making process.[11]

Polyethylenimine is also used as flocculating agent with silica sols and as a chelating agent with the ability to complex metal ions such as zinc and zirconium.[12]

There are also other highly specialized PEI applications:

Biology:
Polyethylenimine has a number of uses in laboratory biology, especially tissue culture, but is also toxic to cells if used in excess.
Toxicity is by two different mechanisms,[15] the disruption of the cell membrane leading to necrotic cell death (immediate) and disruption of the mitochondrial membrane after internalisation leading to apoptosis (delayed).

Attachment promoter
Polyethyleneimines are used in the cell culture of weakly anchoring cells to increase attachment.
Polyethylenimine is a cationic polymer; the negatively charged outer surfaces of cells are attracted to dishes coated in PEI, facilitating stronger attachments between the cells and the plate.
Transfection reagent:
Poly(ethylenimine) was the second polymeric transfection agent discovered,[16] after poly-L-lysine. PEI condenses DNA into positively charged particles, which bind to anionic cell surface residues and are brought into the cell via endocytosis.
Once inside the cell, protonation of the amines results in an influx of counter-ions and a lowering of the osmotic potential.

Osmotic swelling results and bursts the vesicle releasing the polymer-DNA complex (polyplex) into the cytoplasm.
If the polyplex unpacks then the DNA is free to diffuse to the nucleus.


Permeabilization of gram negative bacteria:
Poly(ethylenimine) is also an effective permeabilizer of the outer membrane of Gram-negative bacteria.

CO2 capture
Both linear and branched polyethylenimine have been used for CO2 capture, frequently impregnated over porous materials.
First use of PEI polymer in CO2 capture was devoted to improve the CO2 removal in space craft applications, impregnated over a polymeric matrix.[20]
After that, the support was changed to MCM-41, an hexagonal mesostructured silica, and large amounts of PEI were retained in the so-called "molecular basket".[21]

MCM-41-PEI adsorbent materials led to higher CO2 adsorption capacities than bulk PEI or MCM-41 material individually considered.
The authors claim that, in this case, a synergic effect takes place due to the high PEI dispersion inside the pore structure of the material.
As a result of this improvement, further works were developed to study more in depth the behaviour of these materials.

Exhaustive works have been focused on the CO2 adsorption capacity as well as the CO2/O2 and CO2/N2 adsorption selectivity of several MCM-41-PEI materials with PEI polymers.
Also, PEI impregnation has been tested over different supports such as a glass fiber matrix [24] and monoliths.[25]

However, for an appropriate performance under real conditions in post-combustion capture (mild temperatures between 45-75 °C and the presence of moisture) it is necessary to use thermally and hydrothermally stable silica materials, such as SBA-15,[26] which also presents an hexagonal mesostructure.
Moisture and real world conditions have also been tested when using PEI-impregnated materials to adsorb CO2 from the air.[27]

A detailed comparison among PEI and other amino-containing molecules showed an excellent performance of PEI-containing samples with cycles.
Also, only a slight decrease was registered in their CO2 uptake when increasing the temperature from 25 to 100 °C, demonstrating a high contribution of chemisorption to the adsorption capacity of these solids.
For the same reason, the adsorption capacity under diluted CO2 was up to 90% of the value under pure CO2 and also, a high unwanted selectivity towards SO2 was observed.[28]

Lately, many efforts have been made in order to improve PEI diffusion within the porous structure of the support used.
A better dispersion of PEI and a higher CO2 efficiency (CO2/NH molar ratio) were achieved by impregnating a template-occluded PE-MCM-41 material rather than perfect cylindrical pores of a calcined material,[29] following a previously described route.[30]

The combined use of organosilanes such as aminopropyl-trimethoxysilane, AP, and PEI has also been studied.
The first approach used a combination of them to impregnate porous supports, achieving faster CO2-adsorption kinetics and higher stability during reutilization cycles, but no higher efficiencies.[31]
A novel method is the so-called "double-functionalization".

It is based on the impregnation of materials previously functionalized by grafting (covalent bonding of organosilanes).
Amino groups incorporated by both paths have shown synergic effects, achieving high CO2 uptakes up to 235 mg CO2/g (5.34 mmol CO2/g).[32]
CO2 adsorption kinetics were also studied for these materials, showing similar adsorption rates as impregnated solids.[33]

This is an interesting finding, taking into account the smaller pore volume available in double-functionalized materials.
Thus, it can be also concluded that their higher CO2 uptake and efficiency compared to impregnated solids can be ascribed to a synergic effect of the amino groups incorporated by two methods (grafting and impregnation) rather than to a faster adsorption kinetics.

Low work function modifier for electronics:
Poly(ethylenimine) and poly(ethylenimine) ethoxylated (PEIE) have been shown as effective low-work function modifiers for organic electronics by Zhou and Kippelen et al.[34]
Polyethylenimine could universally reduce the work function of metals, metal oxides, conducting polymers and graphene, and so on.
Polyethylenimine is very important that low-work function solution-processed conducting polymer could be produced by the PEI or PEIE modification.

Based on this discovery, the polymers have been widely used for organic solar cells, organic light-emitting diodes, organic field-effect transistors, perovskite solar cells, perovskite light-emitting diodes, quantum-dot solar cells and light-emitting diodes etc.
Use in delivery of HIV-gene therapies:
Polyethylenimine (PEI), a cationic polymer, has been widely studied and shown great promise as an efficient gene delivery vehicle.
Likewise, the HIV-1 Tat peptide, a cell-permeable peptide, has been successfully used for intracellular gene delivery



SAFETY INFORMATION ABOUT POLYETHYLENEIMINE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.


POLYETHYLENEIMINE (PEI)
DESCRIPTION:
Polyethylenimine (PEI) or polyaziridine is a polymer with repeating units composed of the amine group and two carbon aliphatic CH2CH2 spacers.
Linear polyethyleneimines contain all secondary amines, in contrast to branched PEIs which contain primary, secondary and tertiary amino groups.
Totally branched, dendrimeric forms were also reported.

CAS Number: 9002-98-6


PEI is produced on an industrial scale and finds many applications usually derived from its polycationic character.
Polyethylenimine (PEI) is a hydrophilic cationic polymer widely used as a nonviral nucleotide delivery reagent.
Branched PEI can be synthesized by cationic ring-opening polymerization of aziridine.

PEI-based particles can also be used as adjuvants for vaccines.
Owing to its excellent physicochemical properties, it is applied in many fields like the separation and purification of proteins, carbon dioxide absorption, drug carriers, effluent treatment, and biological labels



PROPERTIES OF POLYETHYLENIMINE (PEI):
The linear PEI is a semi-crystalline solid at room temperature while branched PEI is a fully amorphous polymer existing as a liquid at all molecular weights.
Linear polyethyleneimine is soluble in hot water, at low pH, in methanol, ethanol, or chloroform.
Polyethylenimine is insoluble in cold water, benzene, ethyl ether, and acetone.

Linear polyethyleneimine has a melting point of around 67 °C.
Both linear and branched polyethyleneimine can be stored at room temperature.
Linear polyethyleneimine is able to form cryogels upon freezing and subsequent thawing of its aqueous solutions.


SYNTHESIS OF POLYETHYLENIMINE (PEI):
Branched PEI can be synthesized by the ring opening polymerization of aziridine.
Depending on the reaction conditions different degree of branching can be achieved.
Linear PEI is available by post-modification of other polymers like poly(2-oxazolines) or N-substituted polyaziridines.


Linear PEI was synthesised by the hydrolysis of poly(2-ethyl-2-oxazoline) and sold as jetPEI.

The current generation in-vivo-jetPEI uses bespoke poly(2-ethyl-2-oxazoline) polymers as precursors.



APPLICATIONS OF POLYETHYLENIMINE (PEI):
Polyethyleneimine finds many applications in products like: detergents, adhesives, water treatment agents and cosmetics.
Owing to its ability to modify the surface of cellulose fibres, PEI is employed as a wet-strength agent in the paper-making process.
Polyethylenimine (PEI) is also used as flocculating agent with silica sols and as a chelating agent with the ability to complex metal ions such as zinc and zirconium.

There are also other highly specialized PEI applications:
Biology:
PEI has a number of uses in laboratory biology, especially tissue culture, but is also toxic to cells if used in excess.
Toxicity is by two different mechanisms, the disruption of the cell membrane leading to necrotic cell death (immediate) and disruption of the mitochondrial membrane after internalisation leading to apoptosis (delayed).

Attachment promoter:
Polyethyleneimines are used in the cell culture of weakly anchoring cells to increase attachment.
PEI is a cationic polymer; the negatively charged outer surfaces of cells are attracted to dishes coated in PEI, facilitating stronger attachments between the cells and the plate.


Transfection reagent:
Poly(ethylenimine) was the second polymeric transfection agent discovered,after poly-L-lysine.
PEI condenses DNA into positively charged particles, which bind to anionic cell surface residues and are brought into the cell via endocytosis.
Once inside the cell, protonation of the amines results in an influx of counter-ions and a lowering of the osmotic potential.

Osmotic swelling results and bursts the vesicle releasing the polymer-DNA complex (polyplex) into the cytoplasm.
If the polyplex unpacks then the DNA is free to diffuse to the nucleus.

Permeabilization of gram negative bacteria:
Poly(ethylenimine) is also an effective permeabilizer of the outer membrane of Gram-negative bacteria.

CO2 CAPTURE:
Both linear and branched polyethylenimine have been used for CO2 capture, frequently impregnated over porous materials.
First use of PEI polymer in CO2 capture was devoted to improve the CO2 removal in space craft applications, impregnated over a polymeric matrix.

After that, the support was changed to MCM-41, an hexagonal mesostructured silica, and large amounts of PEI were retained in the so-called "molecular basket".
MCM-41-PEI adsorbent materials led to higher CO2 adsorption capacities than bulk PEI or MCM-41 material individually considered.

The authors claim that, in this case, a synergic effect takes place due to the high PEI dispersion inside the pore structure of the material.
As a result of this improvement, further works were developed to study more in depth the behaviour of these materials.
Exhaustive works have been focused on the CO2 adsorption capacity as well as the CO2/O2 and CO2/N2 adsorption selectivity of several MCM-41-PEI materials with PEI polymers.

Also, PEI impregnation has been tested over different supports such as a glass fiber matrix and monoliths.
However, for an appropriate performance under real conditions in post-combustion capture (mild temperatures between 45-75 °C and the presence of moisture) it is necessary to use thermally and hydrothermally stable silica materials, such as SBA-15, which also presents an hexagonal mesostructure.

Moisture and real world conditions have also been tested when using PEI-impregnated materials to adsorb CO2 from the air.
A detailed comparison among PEI and other amino-containing molecules showed an excellent performance of PEI-containing samples with cycles.
Also, only a slight decrease was registered in their CO2 uptake when increasing the temperature from 25 to 100 °C, demonstrating a high contribution of chemisorption to the adsorption capacity of these solids.

For the same reason, the adsorption capacity under diluted CO2 was up to 90% of the value under pure CO2 and also, a high unwanted selectivity towards SO2 was observed.
Lately, many efforts have been made in order to improve PEI diffusion within the porous structure of the support used.
A better dispersion of PEI and a higher CO2 efficiency (CO2/NH molar ratio) were achieved by impregnating a template-occluded PE-MCM-41 material rather than perfect cylindrical pores of a calcined material, following a previously described route.

The combined use of organosilanes such as aminopropyl-trimethoxysilane, AP, and PEI has also been studied.
The first approach used a combination of them to impregnate porous supports, achieving faster CO2-adsorption kinetics and higher stability during reutilization cycles, but no higher efficiencies.

A novel method is the so-called "double-functionalization".
It is based on the impregnation of materials previously functionalized by grafting (covalent bonding of organosilanes).
Amino groups incorporated by both paths have shown synergic effects, achieving high CO2 uptakes up to 235 mg CO2/g (5.34 mmol CO2/g).

CO2 adsorption kinetics were also studied for these materials, showing similar adsorption rates as impregnated solids.
This is an interesting finding, taking into account the smaller pore volume available in double-functionalized materials.
Thus, it can be also concluded that their higher CO2 uptake and efficiency compared to impregnated solids can be ascribed to a synergic effect of the amino groups incorporated by two methods (grafting and impregnation) rather than to a faster adsorption kinetics.

Low work function modifier for electronics :
Poly(ethylenimine) and poly(ethylenimine) ethoxylated (PEIE) have been shown as effective low-work function modifiers for organic electronics by Zhou and Kippelen et al.
It could universally reduce the work function of metals, metal oxides, conducting polymers and graphene, and so on.
It is very important that low-work function solution-processed conducting polymer could be produced by the PEI or PEIE modification.

Based on this discovery, the polymers have been widely used for organic solar cells, organic light-emitting diodes, organic field-effect transistors, perovskite solar cells, perovskite light-emitting diodes, quantum-dot solar cells and light-emitting diodes etc.

USE IN DELIVERY OF HIV-GENE THERAPIES:
Polyethylenimine (PEI), a cationic polymer, has been widely studied and shown great promise as an efficient gene delivery vehicle.
Likewise, the HIV-1 Tat peptide, a cell-permeable peptide, has been successfully used for intracellular gene delivery

Polyethyleneimine can be used as a non-viral synthetic polymer vector for in vivo delivery of therapeutic nucleic acids.
The interaction between negatively charged nucleic acids and positively charged polymer backbone results in the formation of nano-sized complexes.
This neutralized complex protects the enclosed nucleic acid from enzymes and maintains its stability till the cellular uptake takes place.

For example, human serum albumin conjugated PEI shows good pDNA transfection and low toxicity.

PEI can be used to functionalize single-walled nanotubes (SWNTs) to improve their solubility and biocompatibility while maintaining the structural integrity of the original SWNT.
Covalently functionalized SWNTs find application in CO2 absorption and gene delivery.

Branched PEI can also be used to modify the surface properties of adsorbents.
PEI-modified hydrous zirconium oxide/PAN nanofibers are used for the defluorination of groundwater as they show high fluoride adsorption capacity and a wide working pH range.

FEATURES AND BENEFITS OF POLYETHYLENEIMINE:
Primary and secondary amine groups of PEI can efficiently bind to drugs, nucleic acids, and other functional moieties.

Branched PEI has better complexation and buffering capacity.










CHEMICAL AND PHYSICAL PROPERTIES OF POLYETHYLENEIMINE (PEI):
Chemical formula, (C2H5N)n, linear form
Molar mass, 43.04 (repeat unit), mass of polymer variable
form
viscous liquid
mol wt
average Mn ~10,000 by GPC
average Mw ~25,000 by LS

impurities
≤1% water
refractive index
n20/D 1.5290
viscosity
13,000-18,000(50 °C)
bp
250 °C (lit.)
density
1.030 g/mL at 25 °C
Melting point, 59-60°C
Boiling point, 250 °C(lit.)
Density, 1.030 g/mL at 25 °C
vapor pressure, 9 mmHg ( 20 °C)
refractive index, n20/D 1.5290
Flash point, >230 °F
storage temp., 2-8°C
solubility, DMSO (Sparingly)
form, Liquid
color, Pale yellow
Specific Gravity, 1.045 (20/4℃)
PH, pH(50g/l, 25℃) : 10~12
Water Solubility, Soluble in water.
Sensitive, Hygroscopic
InChI, InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChIKey, NOWKCMXCCJGMRR-UHFFFAOYSA-N
SMILES, C1NC1
LogP, -0.969 (est)





SAFETY INFORMATION ABOUT POLYETHYLENEIMINE (PEI):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product




SYNONYMS OF POLYETHYLENEIMINE (PEI):
PEI-10
polyethyleneimine, branched, m.w. 1800
Aziridine,homopolymer
polyethylenimine(10,000)
POLYETHYLENEIMINE, BRANCHED
PEI-35
PEI-2500
PEI-1500
polyethylenimine(20,000);
Ethyleneimine,homopolymer


POLYETHYLENIMINE (PEI)
Polyethylenimine (PEI) is highly branched liquid water soluble polyamine with high cationic charge density.
Polyethylenimine (PEI) is a high-charge cationic polymer that readily binds highly anionic substrates.
Polyethylenimine (PEI) is a clear viscous liquid.


CAS Number: 9002-98-6
MDL number: MFCD00084427
Linear Formula: H(NHCH2CH2)nNH2
Chemical formula: (C2H5N)n, linear form



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200, epomin sp 003, dow pei-18, pei-10, montrek 6, epomin p 1500, el 402, polymin g 100, pei-275, lupasol wf, epomin sp 012, ethylenimine, polymers, pei-250, pei-600, epomin sp 1000, epomin d 3000, polymin 6, montrek 1000, everamine 150t, dow pei-6, p 600xe, epomine 150t, dow pei-600e, 15t, lupasol sk, pei 2, epomin sp 018, pei-45, polymin g 35, polymin, epomin sp 006, corcat p 18, pei-7, lugalvan g 15, epomine p 1000, everamine 50t, polymin hs, pei 400, polyethylenimine, m.w.600, pei 600, ethoxylated polyethylenimine, m.w. 60,000, p 0381, epomin 150t, ethylenimine resins, p 1000, 2mb, bufloc 595, pei 1120, polyethyleneimine, 50 % solution in water, lugalvan g 35, pei-14m, corcat p 145, pei-35, pei 12, cf 218 (polymer), corcat p 600, montrek 600, epomine 1000, corcat p 150, epomin p 1000, lugalvan g 20, aziridine homopolymer, montrek 12, emerlube 6717, pei 1, epomin 1000, pei-15, tydex 12, everamine 500t, pei 6, p 100 (polyamine), polymin g 20, corcat p 200, epomin sp 103, lupasol g 20, lupasol fg, p 70 (polyamine), basocoll pr 8086, montrek pei 6, montrek 18, corcat p 12, Polyethylenimine (PEI), corcat p 100, 1/c2h5n/c1-2-3-1/h3h,1-2h, polymin g 500, epomin pp 061, ethylenimine, homopolymer, up 300 (polyamine), adcote 372, lupasol p, el 420, montrek pei 18, ethylenimine polymer, epomin p 1050, paz 33, polymine p, polyethylenimine, m.w.1800, Ethylenimine, polymers, Montrek 1000, PEI 18, Epomin SP 003, Montrek PEI 18, Corcat P 12, Epomin P 500, Montrek PEI 6, XA 1007, Lugalvan G 15, Polyethylenimine, M.W.1800, Polyethylenimine (PEI), Ethylenimine resins, Epomin P 1500, Epomin SP 018, Corcat P 150, Montrek 12, Polymine P, Epomin P 003, P 1000 (polyamine), Ethylenimine, homopolymer, Lupasol WF, Epomin 150T, Polymin HS, EL 420, Dow PEI-600e, Polymin G 20, PAZ 33, Lupasol G 20, Lugalvan G 20, Montrek 6, Everamine 210T, Aziridine homopolymer, Epomin SP 012, UP 300 (polyamine), PEI, P 100 (polyamine), Montrek 18, K 203C, 15T, Epomin P 1000, Epomin SP 1000, Everamine 500T, Polymin P, Tydex 12, 1/C2H5N/c1-2-3-1/h3H,1-2H, Epamine 150T, Corcat P 200, Epomine P 1000, Epomin PP 061, Aziridine,polymers,homopolymer, PEI-600, Adcote 372, PEI 600, PR 20 (release agent), Everamine 50T, Epomin 1000, Epomin SP 006, Polymin 6, Epomin P 1050, Polyethyleneimine, PEI 400, Corcat P 145, PEI 1, PEI 12, Polymin G 100, Basocoll PR 8086, Lupasol G 35, Dow PEI-6, Polymin G 15M, PEI 1000, Ethylenimine polymer, PEI 6, Polyethylenimine, M.W.600, Epomine 1000, Polymin, Epomin SP 200, 2MB, CF 218 (polymer), Everamine, Dow PEI-18, PEI 100, Lupasol SK, Epomin SP 103, P 0381, Lupasol P, Ethoxylated polyethylenimine, M.W. 60,000, Corcat P 600, Epomin D 3000, Polymin G 35, EL 402, Poly (ethylenimine), P 600XE, Epomin SP 110, P 1000, Polymin G 500, Everamine 150T, Lugalvan G 35, PEI 1120, Sedipur CL 930, Epomin SP 300, P 70 (polyamine), Polymin FL, Emerlube 6717, Corcat P 100, PEI 2, Lupasol FG, Epomine 150T, Corcat P 18, Montrek 600, Bufloc 595, Polymin SNA, Polyethyleneimine, 50 % solution in water, epomine 150t, pei-600, polymine p, aziridine,polymers,homopolymer, everamine 50t, polyethyleneimine, lupasol fg, corcat p 145, montrek 12, ethylenimine polymer, p 100 (polyamine), pei-700, corcat p 600, polymin g 35, pei-7, lupasol p, epomin pp 061, corcat p 12, pei-35, epomin p 003, polymin p, pei 400, epomin sp 300, ethylenimine, polymers, up 300 (polyamine), pr 20 (release agent), basocoll pr 8086, 1/c2h5n/c1-2-3-1/h3h,1-2h, montrek 1000, ethylenimine, homopolymer, el 402, lupasol wf, polymin g 20, bufloc 595, pei, ethylenimine resins, aziridine homopolymer, pei 18, el 420, polymin g 100, polymin fl, montrek 18, epomin sp 1000, epomin d 3000, epomin 150t, epomin p 1050, 2mb, everamine 150t, epomin sp 012, pei 12, epomin p 1500, epomin sp 200, p 600xe, dow pei-18, polymin hs, pei 1, sedipur cl 930, polymin sna, polyethylenimine, m.w.1800, pei 6, montrek pei 18, corcat p 100, epomin 1000, epomin p 500, k 203c, corcat p 200, p 0381, everamine 500t, xa 1007, pei-275, p 1000, pei-14m, epomine 1000, pei 1000, lupasol g 20, pei-10, Polyethylenimine (PEI), epomin p 1000, pei 1120, corcat p 150, paz 33, pei-250, epomin sp 103, polyethyleneimine, 50 % solution in water, polymin g 15m, corcat p 18, dow pei-6, lugalvan g 20, polymin 6, ethoxylated polyethylenimine, m.w. 60,000, everamine, lupasol g 35, poly (ethylenimine), 15t, polymin g 500, epomine p 1000, adcote 372, everamine 210t, epomin sp 003, emerlube 6717, polymin, pei 600, pei-45, epomin sp 018, lupasol sk, polyethylenimine, m.w.600, epomin sp 110, pei 2, montrek pei 6, montrek 6, pei 100, pei-15, pei-30, dow pei-600e, lugalvan g 15, montrek 600, epomin sp 006, p 1000 (polyamine), epamine 150t, p 70 (polyamine), cf 218 (polymer), tydex 12, lugalvan g 35, Adcote372MW, Aldrich 408719, Aldrich 482595, Aziridine Polymer, Basocoll PR 8086, Basomin G 500, Basonal White FO 1, Bufloc 595, CF 218, CF 218 (Polymer), CP 8994, Corcat P 100, Corcat P 12, Corcat P 145, Corcat P 150, Corcat P 18, 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Polyethylenimine (PEI), an organic polyamine polymer, is one of the most prominent examples of cationic polymers capable of gene transfection in vitro and in vivo into various cell lines and tissues.
Polyethylenimine (PEI) was also applied in different fields from gene therapy and several studies have emphasized the importance of this polymer in medicinal chemistry.


Polyethylenimine (PEI) is a clear viscous liquid.
Polyethylenimine (PEI) or polyaziridine is a polymer with repeating units composed of the amine group and two carbon aliphatic CH2CH2 spacers.
Linear polyethyleneimines contain all secondary amines, in contrast to branched PEIs which contain primary, secondary and tertiary amino groups.


Polyethylenimine (PEI) has a branched cationic structure with high charge density that enables improved adhesion of dissimilar materials.
Polyethylenimine (PEI) is branched spherical polymeric amines.


Polyethylenimine (PEI) is highly branched liquid water soluble polyamine with high cationic charge density.
Polyethylenimine (PEI) contains primary, secondary, and tertiary amine groups in approximately 25/50/25 ratio.
Polyethylenimine (PEI) branched is a organic macromolecule with high cationic-charge-density potential.


Polyethylenimine (PEI) can ensnare DNA as well as attach to cell membrane, PEI also retains a substantial buffering capacity at virtually any pH.
Polyethylenimine (PEI) is a high-charge cationic polymer that readily binds highly anionic substrates.
Industrially, Polyethylenimine (PEI) can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces.


Polyethylenimine (PEI) is available in water-free and waterborne grades of various molecular weights.
Polyethylenimine (PEI) has the largest possible amino group density of all commercially available polyamines, with a nitrogen-to-carbon ratio of 1:2.
Polyethylenimine (PEI) thus has a high cationic charge density that is strongly dependent on pH, being highest at pH 2–4.


Polyethylenimine (PEI) is generally compatible with non-ionic and cationic systems and incompatible with anionic systems.
Polyethylenimine (PEI) is soluble in water as well as both polar and aprotic nonpolar solvents.
The high charge density of Polyethylenimine (PEI) forms strong bonds on negatively charged surfaces, including cellulose, polyester, polyolefins, polyamides, and metals.


In research, Polyethylenimine (PEI) readily binds to DNA and other negatively charged biological molecules, making it the most efficient vector carriers available.
Polyethylenimine (PEI) is soluble in: hot water, cold water at low pH, methanol and ethanol


Polyethylenimine (PEI) is insoluble in: benzene, ethyl ether and acetone
Polyethylenimine (PEI) is a high-charge cationic polymer that readily binds highly anionic substrates.
Industrially, linear Polyethylenimine (PEI) can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces.


Polyethylenimine (PEI) has a branched cationic structure with high charge density that enables improved adhesion of dissimilar materials.
Polyethylenimine (PEI) can be used as a formulation additive or primer coat for: adhesion promotion, pigment stabilization, and increased particle cohesion.
Polyethylenimine (PEI) is obtained from the polymerization of ethylenimine, this line of polymers is available in a wide range of molecular weights (from 800 -106 g/mol).


Polyethylenimine (PEI) products are water soluble and also exhibit good solubility in polar solvents with the added benefit of having a strong eco-toxicological profile including several food contact compliances.
Polyethylenimine (PEI) is branched spherical polymeric amines.


In research, Polyethylenimine (PEI) readily binds to DNA and other negatively charged biological molecules, making it the most efficient vector carriers available.
Polyethylenimine (PEI) polymers are suitable solutions for a wide range of adhesive applications.


Polyethylenimine (PEI) (molecular weight 40,000) is a highly charged cationic polymer that readily binds to DNA or other negatively charged biomacromolecules, making it a common and effective cell transfection reagent.
In principle, Polyethylenimine (PEI) condenses DNA plasmid into positively charged complexes.


The complexes can adhere to negatively charged cell surface residues, and then enters the cell through endocytosis.
As a transient transfection reagent, Polyethylenimine (PEI) has the advantages of high efficiency, low cost and relative stability, etc., which has been validated for a wide range of common cell lines including HEK-293, HEK293T, CHO-K1, HepG2 and Hela cell transfection.


In HEK293 and CHO cell expression systems, Polyethylenimine (PEI) provides excellent transfection results at different sizes (from 96-well plates to 100 L bioreactors).
Polyethylenimine (PEI) is widely utilized in Industrial settings, numerous Research fields, and a plethora of other distinctive applications.


Polyethylenimine (PEI) is one of the polyethyleneimines which may be used according to the patent in suit as the "primary and/or secondary amine compound having an Odor Intensity index of less than that of a 1% solution of methylanthranilate in dipropylene glycol".
Polyethylenimine (PEI) is a powder, or liquid


Polyethylenimine (PEI) belongs to the categories of Polymers; Amine-Functional Polymers; Hydrophilic Polymers; Polymer Science.
Polyethylenimine (PEI)'s cas registry number is 9002-98-6.
Polyethylenimine (PEI) is also called Aziridine, homopolymer ; Ethylenimine, polymers (8CI) ; Polyethylenimine (10,000) ; Polyethylenimine (20,000) ; Polyethylenimine (35,000) .


Polyethylenimine (PEI), also known as CAS Number: 9002-98-6, is a multi-functional linear polymer with an average molecular weight of 5,000 and a minimum Polydispersity Index (PDI) of 1.3.
Polyethylenimine (PEI) is a high-performing polymer identified primarily by CAS Number 9002-98-6.


Polyethylenimine (PEI)'s a linear compound noted for its remarkable attributes and versatile applications across myriad industrial, research, and other sectors.
With a linear average molecular weight of 5,000 and a Polydispersity Index (PDI) exceeding 1.3, Polyethylenimine (PEI) stands out as an essential component in many processes.


Polyethylenimine (PEI) or polyaziridine is a polymer with repeating unit composed of the amine group and two carbon aliphatic CH2CH2 spacer.
Linear Polyethylenimines (PEI) contain all secondary amines, in contrast to branched Polyethylenimine (PEI)s which contain primary, secondary and tertiary amino groups.


Totally branched, dendrimeric forms were also reported.
Polyethylenimine (PEI) magnetic particles are superparamagnetic beads covalently functionalized with PEI.
Polyethylenimine (PEI) is a kind of branched polymer with a high-density amine group.


The ratio of primary amine to secondary amine to tertiary amine is 1:2:1.
In each Polyethylenimine (PEI) molecule, one nitrogen atom in every two carbon atoms is protonated.
Due to the different pKa values of primary, secondary, and tertiary amino groups, Polyethylenimine (PEI) could capture protons under different pH conditions, which is called the "proton sponge" mechanism.


As a cationic polymer, Polyethylenimine (PEI) is also a widely used transfection reagent in molecular biology and a dispersant in nanotechnology.
Polyethylenimine (PEI) can form a positively charged complex with DNA, which binds to anionic cell surface residues and enters the cell via endocytosis. Polyethylenimine (PEI) is available with an organic matrix of a polystyrene polymer.


The Polyethylenimine (PEI) magnetic particles can capture negatively charged molecules, such as DNA and RNA, through charge-charge interaction.
Polyethylenimine (PEI) is a cationic polymer containing a large number of nitrogen atoms,which usually has a highly branched structure.
Polyethylenimine (PEI) has good solubility,adsorption,and reducibility,and has important functions in many applications.


Polyethylenimine (PEI) in detail along with its key properties like mechanical, thermal, electrical, etc. and understand what makes it an ideal choice in high-end engineering applications.
Polyethylenimine (PEI) is a powerful, trusted, and cost-effective transient transfection reagent.


Polyethylenimine (PEI) improves in vitro and in vivo delivery of oligonucleotides and nucleic acids (DNA, siRNA, mRNA), and improve transfection efficiency.
Polyethylenimine (PEI) is a saturated organic heteromonocyclic parent, a member of aziridines and an azacycloalkane.
Polyethylenimine (PEI) has a role as an alkylating agent.


Polyethylenimine (PEI) is a conjugate base of an aziridinium.
All polyethylene imine polymers are hydrophilic and may contain approx. 30% hydrated water.
Polyethylenimine (PEI) is a highly charged cationic polymer that easily binds negatively charged nucleic acid molecules, forms a complex, and allows the complex to enter the cell.



USES and APPLICATIONS of POLYETHYLENIMINE (PEI):
Polyethylenimine (PEI) acts as a protein precipitant used to purify proteins.
Polyethylenimine (PEI) is used as a chelating agent and as a scavenger for aldehydes and oxides.
Polyethylenimine (PEI) is also used in detergents, paper industry, dyes, printing inks and in water treatment.


Polyethylenimine (PEI) is widely used in many applications due to its polycationic character.
Unlike its linear equivalent, branched Polyethylenimine (PEI) contains primary, secondary, and tertiary amines.
Primarily utilized in industrial applications, high molecular weight Polyethylenimine (PEI) has been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture.


Polyethylenimine (PEI) is used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.
Polyethylenimine (PEI) is used detergents, adhesives, water treatment, printing inks, dyes, cosmetics, and paper industry, adhesion promoter, lamination primer, fixative agent, flocculant, cationic dispersant, stability enhancer, surface activator, chelating agent, scavenger for aldehydes and oxides.


Polyethylenimine (PEI) is used Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals.
Applications of Polyethylenimine (PEI): Paints & Coatings — Building & Construction, Architectural Coatings, Building & Construction — Building Envelope & Roofing, Architectural Coatings, Industrial — Leather & Textiles, and Textile Manufacturing.


Due to their high charge density Polyethylenimine (PEI) adsorbs tightly on negatively charged surfaces.
This mode of action can be applied to a huge variety of materials, such as cellulose, polyesters, polyolefines, polyamides, and metals, and provides visible advantages to the user.


Polyethylenimine (PEI) is the ideal adhesion promoter between different types of plastics or between plastics and polar substrates, such as polyolefine films and paper.
Polyethylenimine (PEI) improves dye acceptance, paintability, and barrier properties
In lamination inks, Polyethylenimine (PEI) acts as a tie-bond for the plastic film placed over the substrate.


Polyethylenimine (PEI) can be used as a non-viral synthetic polymer carrier for in vivo delivery of therapeutic nucleic acids.
The interaction between the negatively charged nucleic acid and the positively charged polymer backbone leads to the formation of nanoscale complexes.
This neutralising complex protects the enclosed nucleic acid from enzymes and maintains Polyethylenimine (PEI)'s stability until cellular uptake occurs.


For example, human serum albumin-coupled PEI shows good pDNA transfection and low toxicity.
Polyethylenimine (PEI) can be used to functionalize single-walled nanotubes (SWNTs) to improve their solubility and biocompatibility while maintaining the structural integrity of the original SWNT.


Covalently functionalized SWNTs can be used for CO2 uptake and gene delivery.
Polyethylenimine (PEI) can also be used to modify the surface properties of adsorbents.
Polyethylenimine (PEI)-modified aqueous zirconia/PAN nanofibres have a high fluoride adsorption capacity and a wide working pH range, and can therefore be used for groundwater defluoridation.


Polyethylenimine (PEI) is produced on industrial scale and finds many applications usually derived from its polycationic character.
Polyethylenimine (PEI) is used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.
Totally branched, dendrimeric forms were also reported.


Polyethylenimine (PEI) is used Adhesion Promoter; Compatibilizer; Plastic Adhesion; Impart Paintability; Barrier Coating; Tie-Bond; Lamination Adhesives
Polyethylenimine (PEI) is multifunctional, cationic, branched polyethyleneimines (PEI).
Polyethylenimine (PEI) is used as adhesion promoters, primers, compatibilizers, and flocculants for multiple applications and substrates.


Polyethylenimine (PEI) may be used as an adhesion promoter for printing inks used on plastic films.
For inkjet inks, Polyethylenimine (PEI) increases resolution and water fastness on paper.
Polyethylenimine (PEI) may also be used as a primer to increase the surface energy of a variety of plastic films and metal foils, making them more receptive to applying adhesives to form multilayer flexible packaging.


For applications where Polyethylenimine (PEI) is used as an adhesion promoter, an appropriate grade to select is one having a similar molecular weight to the other polymers in the system.
In coating applications, Polyethylenimine (PEI) can impart tie-layer and paint adhesion.


Polyethylenimine (PEI) is produced on an industrial scale and finds many applications usually derived from its polycationic character.
Polyethyleneimine finds many applications in products like: detergents, adhesives, water treatment agents and cosmetics.
Owing to its ability to modify the surface of cellulose fibres, Polyethylenimine (PEI) is employed as a wet-strength agent in the paper-making process.


Polyethylenimine (PEI) is also used as flocculating agent with silica sols and as a chelating agent with the ability to complex metal ions such as zinc and zirconium.
Biology uses of Polyethylenimine (PEI): Polyethylenimine (PEI) has a number of uses in laboratory biology, especially tissue culture.


Polyethylenimine (PEI) is widely used as transfection reagent.
Coatings and Adhesives: Polyethylenimine (PEI) contributes significantly to the formulation of coatings and adhesives, lending them exceptional bonding properties.


Wet adhesion of paints may be improved by blending a small concentration of Polyethylenimine (PEI)into the formula.
Polyethylenimine (PEI) is particularly useful as a primer in UV curing systems to improve adhesion where volume shrinkage occurs.
Lower molecular weight Polyethylenimine (PEI) grades are useful as cross-linkers for coating and adhesive formulations, where they increase cohesive strength while maintaining the same level of adhesion.


The high positive charge density mentioned also allows high molecular weight grades of Polyethylenimine (PEI) to flocculate highly charged, anionic particles such as proteins, zeolites, and silicates.
This property makes Polyethylenimine (PEI) useful in water treatment and protein immobilization applications.


Textiles: The textile industry utilizes Polyethylenimine (PEI) in their finishing processes to enhance fabric properties such as water resistance and color fastness.
Paper Manufacturing: Polyethylenimine (PEI)’s function as a wet-strength agent enhances the durability and strength of paper products.


Oil and Gas: Polyethylenimine (PEI) is integral to the oil and gas industry as it improves the flow properties of petroleum products.
Gene Delivery: Polyethylenimine (PEI) is a preferred transfection agent for gene delivery, facilitating efficient genetic material transfer into cells.
Nanoparticle Synthesis: Polyethylenimine (PEI) aids in the controlled synthesis of nanoparticles, acting as a stabilizing agent.


Surface Modification: Polyethylenimine (PEI) is used for surface modifications, enhancing adhesion and improving surface properties.
Biomedical Engineering: In biomedical engineering, Polyethylenimine (PEI) is used in tissue engineering scaffolds, drug delivery systems, and diagnostic assays.


Water Treatment: Polyethylenimine (PEI) proves beneficial in removing heavy metals and organic contaminants in water treatment processes.
Photography: In the field of photography, Polyethylenimine (PEI) is used as a wetting agent and as a constituent in developer solutions.
Personal Care: Polyethylenimine (PEI) is a popular addition in personal care products for its moisturizing and detangling properties.


Characterized by a combination of outstanding thermal, mechanical and electrical properties, Polyethylenimine (PEI) has made its place in high performance applications like automotive, aerospace, industrial and many more.
Polyethylenimine (PEI) is used Capturing negatively charged molecules, Transfection reagent and dispersant, and DNA and protein concentration.


Polyethylenimine (PEI) is a powerful, trusted, and cost-effective reagent widely considered as a current gold standard for both in vitro and in vivo transfection.
Polyethylenimine (PEI) has a high density of protonatable amino groups, with amino nitrogen as every third atom.


This imparts a high buffering ability at nearly any pH.
Hence, once inside the endosome, Polyethylenimine (PEI) disrupts the vacuole and releases the genetic material into the cytoplasm.


Stable complexation with DNA, efficient entry into the cell, and ability to escape the endosome makes Polyethylenimine (PEI) a highly efficient transfection reagent which is compatible for a wide range of cell lines/types including the most commonly used HEK293 and CHO cells grown in adherent and suspension cultures.


Polyethylenimine (PEI) has multiple industrial, medical, biological and research applications.
Polyethylenimine (PEI) is a difficult compound to analyze by HPLC.
The problem has many degrees of difficulty.


Polyethylenimine (PEI) is not a single compound, but a mixture of different molecules with different lengths and branching structures.
Polyethylenimine (PEI) has multiple charges in acidic and neutral pH, which is most common in HPLC PEI molecules have no UV chromophores and can not be measured by UV-Vis detector, the most common detector in analytical laboratories.


Instead, this analysis requires MS, CAD, ELSD with their own limitations of the mobile phase composition.
Polyethylenimine (PEI) irreversibly binds to silica-based columns, limiting the type of adsorbents that can be used for analysis.
If composition of Polyethylenimine (PEI) with proteins or peptides needs to be analyzed then the peptide/protein signal can interfere with PEI peak SIELC developed a new methodology and a corresponding HPLC column to address these difficulties and offer a simple and reliable method for PEI quantitation in any liquid samples.


The method is based on forming a complex of Polyethylenimine (PEI) with Cu (II) which has strong UV and visible light adsorption maximums.
This complex can be measured by UV-Vis detector and can be separated from Cu (II) signal and other Cu complexes using specially designed Polyethylenimine (PEI) specific HPLC column.


-Attachment promoteruses of Polyethylenimine (PEI):
Polyethylenimine (PEI) is used in the cell culture of weakly anchoring cells to increase attachment.
Polyethylenimine (PEI) is a cationic polymer; the negatively charged outer surfaces of cells are attracted to dishes coated in PEI, facilitating stronger attachments between the cells and the plate.


-Transfection reagent uses of Polyethylenimine (PEI):
Poly(ethylenimine) was the second polymeric transfection agent discovered, after poly-L-lysine.
Polyethylenimine (PEI) condenses DNA into positively charged particles, which bind to anionic cell surface residues and are brought into the cell via endocytosis.

Once inside the cell, protonation of the amines results in an influx of counter-ions and a lowering of the osmotic potential.
Osmotic swelling results and bursts the vesicle releasing the polymer-DNA complex (polyplex) into the cytoplasm.
If the polyplex unpacks then the DNA is free to diffuse to the nucleus.
Permeabilization of gram negative bacteria Polyethylenimine (PEI) is also an effective permeabilizer of the outer membrane of Gram-negative bacteria.



LOW WORK FUNCTION MODIFIER FOR ELECTRONICS, POLYETHYLENIMINE (PEI):
Polyethylenimine (PEI) and poly(ethylenimine) ethoxylated (PEIE) have been shown as effective low-work function modifiers for organic electronics by Zhou and Kippelen et al.
Polyethylenimine (PEI) could universally reduce the work function of metals, metal oxides, conducting polymers and graphene, and so on.

Polyethylenimine (PEI) is very important that low-work function solution-processed conducting polymer could be produced by the Polyethylenimine (PEI) or PEIE modification.
Based on this discovery, Polyethylenimine (PEI) has been widely used for organic solar cells, organic light-emitting diodes, organic field-effect transistors, perovskite solar cells, perovskite light-emitting diodes, quantum-dot solar cells and light-emitting diodes etc.



USE IN DELIVERY OF HIV-GENE THERAPIES, POLYETHYLENIMINE (PEI):
Polyethylenimine (PEI), a cationic polymer, has been widely studied and shown great promise as an efficient gene delivery vehicle.
Likewise, the HIV-1 Tat peptide, a cell-permeable peptide, has been successfully used for intracellular gene delivery.



FEATURES OF POLYETHYLENIMINE (PEI):
*Superior Performance:
High transfection efficiency with low cytotoxicity.

*Flexible Workflow:
Easy to optimize and introduce into application protocols.
Scalable for well plates, flasks, and larger capacity bioreactors.

*Cost-Effective:
Economical compared to similar transfection products in the market.



PROPERTIES OF POLYETHYLENIMINE (PEI):
The linear Polyethylenimine (PEI) is a semi-crystalline solid at room temperature while branched Polyethylenimine (PEI) is a fully amorphous polymer existing as a liquid at all molecular weights.
Linear Polyethylenimine (PEI) is soluble in hot water, at low pH, in methanol, ethanol, or chloroform.

Polyethylenimine (PEI) is insoluble in cold water, benzene, ethyl ether, and acetone.
Linear Polyethylenimine (PEI) has a melting point of around 67 °C.
Both linear and branched Polyethylenimine (PEI) can be stored at room temperature.
Linear Polyethylenimine (PEI) is able to form cryogels upon freezing and subsequent thawing of its aqueous solutions.



FEATURES OF POLYETHYLENIMINE (PEI):
*Improved Color Acceptance



SYNTHESIS OF POLYETHYLENIMINE (PEI):
Branched Polyethylenimine (PEI) can be synthesized by the ring opening polymerization of aziridine.
Depending on the reaction conditions different degree of branching can be achieved.
Linear Polyethylenimine (PEI) is available by post-modification of other polymers like poly(2-oxazolines) or N-substituted polyaziridines.
Linear Polyethylenimine (PEI) was synthesised by the hydrolysis of poly(2-ethyl-2-oxazoline) and sold as jetPEI.
The current generation in-vivo-jet Polyethylenimine (PEI) uses bespoke poly(2-ethyl-2-oxazoline) polymers as precursors.



UNMATCHED QUALITIES OF POLYETHYLENIMINE (PEI):
The versatility of Polyethylenimine (PEI) lies in its unique properties which include outstanding adhesion and bonding attributes.
It's these traits that have led to Polyethylenimine (PEI) being a choice compound in numerous areas of application.



PRODUCTION METHODS OF POLYETHYLENIMINE (PEI):
Polyethylenimine (PEI) is produced by the homopolymerization of ethylenimine.
The reaction is catalyzed by acids, Lewis acids, or haloalkanes.
The polymerization is usually carried out at 90 – 110 ℃ in water or in a variety of organic solvents.

The average molecular mass of the Polyethylenimine (PEI) prepared as described above is 10 000 – 20 000.
Higher molecular mass polymers are prepared by addition of a difunctional alkylating agent, such as chloromethyloxirane or 1,2-dichloroethane.
Polyethylenimines (PEI) with a higher average molecular mass can also be provided by ultrafiltration of polymers with a broad mass distribution.
Likewise, polymers of lower molecular mass can be obtained by inclusion of a low molecular mass amine, such as 1,2- ethanediamine, during polymerization.

By using these techniques a range of molecular masses from 300 to 10 6 can be obtained.
Cross-linking during the polymerization of ethylenimine in organic solvents leads to solid Polyethylenimines (PEI).
Furthermore the polymerization process can be conducted on the surface of organic or inorganic materials, thus fixing the Polyethylenimines (PEI) to a support.



STRUCTURE AND CONFORMATION OF POLYETHYLENIMINE (PEI):
Polyethylenimine (PEI) exists as both a branched and linear structure.
Branched Polyethylenimine (PEI) (bPEI) is synthesized via acid-catalyzed polymerization of aziridine, whereas the linear structure (lPEI) is synthesized via ring opening polymerization of 2-ethyl-2-oxazoline followed by hydrolysis.



BIOLOGICAL ACTIVITY OF POLYETHYLENIMINE (PEI):
Polyethylenimine (PEI) is nondegradable and the molecular weight of PEI affects the cytotoxicity and gene transfer activity.
Polyethylenimine (PEI) acts as a low toxicity and efficient gene vector.



CO2 CAPTURE, POLYETHYLENIMINE (PEI):
Both linear and branched Polyethylenimine (PEI) have been used for CO2 capture, frequently impregnated over porous materials.
First use of Polyethylenimine (PEI) polymer in CO2 capture was devoted to improve the CO2 removal in space craft applications, impregnated over a polymeric matrix.

After that, the support was changed to MCM-41, an hexagonal mesostructured silica, and large amounts of Polyethylenimine (PEI) were retained in the so-called "molecular basket".
MCM-41-PEI adsorbent materials led to higher CO2 adsorption capacities than bulk Polyethylenimine (PEI) or MCM-41 material individually considered.

The authors claim that, in this case, a synergic effect takes place due to the high Polyethylenimine (PEI) dispersion inside the pore structure of the material.
As a result of this improvement, further works were developed to study more in depth the behaviour of these materials.

Exhaustive works have been focused on the CO2 adsorption capacity as well as the CO2/O2 and CO2/N2 adsorption selectivity of several MCM-41-PEI materials with Polyethylenimine (PEI) polymers.
Also, Polyethylenimine (PEI) impregnation has been tested over different supports such as a glass fiber matrix and monoliths.

However, for an appropriate performance under real conditions in post-combustion capture (mild temperatures between 45-75 °C and the presence of moisture) it is necessary to use thermally and hydrothermally stable silica materials, such as SBA-15, which also presents an hexagonal mesostructure.
Moisture and real world conditions have also been tested when using Polyethylenimine (PEI)-impregnated materials to adsorb CO2 from the air.

A detailed comparison among Polyethylenimine (PEI) and other amino-containing molecules showed an excellent performance of PEI-containing samples with cycles.
Also, only a slight decrease was registered in their CO2 uptake when increasing the temperature from 25 to 100 °C, demonstrating a high contribution of chemisorption to the adsorption capacity of these solids.

For the same reason, the adsorption capacity under diluted CO2 was up to 90% of the value under pure CO2 and also, a high unwanted selectivity towards SO2 was observed.
Lately, many efforts have been made in order to improve Polyethylenimine (PEI) diffusion within the porous structure of the support used.

A better dispersion of Polyethylenimine (PEI) and a higher CO2 efficiency (CO2/NH molar ratio) were achieved by impregnating a template-occluded PE-MCM-41 material rather than perfect cylindrical pores of a calcined material, following a previously described route.
The combined use of organosilanes such as aminopropyl-trimethoxysilane, AP, and Polyethylenimine (PEI) has also been studied.

The first approach used a combination of them to impregnate porous supports, achieving faster CO2-adsorption kinetics and higher stability during reutilization cycles, but no higher efficiencies.
A novel method is the so-called "double-functionalization".

It is based on the impregnation of materials previously functionalized by grafting (covalent bonding of organosilanes).
Amino groups incorporated by both paths have shown synergic effects, achieving high CO2 uptakes up to 235 mg CO2/g (5.34 mmol CO2/g).
CO2 adsorption kinetics were also studied for these materials, showing similar adsorption rates as impregnated solids.

This is an interesting finding, taking into account the smaller pore volume available in double-functionalized materials.
Thus, it can be also concluded that their higher CO2 uptake and efficiency compared to impregnated solids can be ascribed to a synergic effect of the amino groups incorporated by two methods (grafting and impregnation) rather than to a faster adsorption kinetics.



PHYSICAL and CHEMICAL PROPERTIES of POLYETHYLENIMINE (PEI):
Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable
Melting Point: 59-60°C
Boiling Point: 250 °C(lit.)
Flash Point: >230 °F
Molecular Formula: C2H5N
Molecular Weight: 43.06780
Density: 1.030 g/mL at 25 °C
Physical state: viscous
Color: colorless
Odor: No data available
Melting point/freezing point
Melting point/range: 54 - 59 °C
Initial boiling point and boiling range: 250 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point: > 110 °C - closed cup
Autoignition temperature: > 200 °C
Decomposition temperature: > 250 °C
pH: 11 - DIN 19268
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 15.000 mPa.s at 50 °C
Water solubility soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,030 g/cm3 at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Fòrmula: (C2H5N)x
No. CAS: 9002-98-6
Appearance: Liquid
Color: Colorless to light yellow
SMILES: NCCN(CCN)CCN(CCCNCN)CCN(CCNCCN)CCNCCN(CCN)CCN.[n]
Appearance (Form): Viscous Liquid
Refractive index: n20/D 1.5290
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C
Impurities: ≤1% water
CBNumber: CB9162514
Molecular Formula:C2H5N
Molecular Weight:43.07
MDL Number:MFCD00803910
MOL File:9002-98-6.mol
Melting point: 59-60°C
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C

vapor pressure: 9 mmHg ( 20 °C)
refractive index: n20/D 1.5290
Flash point: >230 °F
storage temp.: 2-8°C
solubility: DMSO (Sparingly)
form: Liquid
color: Pale yellow
Specific Gravity: 1.045 (20/4℃)
PH: pH(50g/l, 25℃) : 10~12
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
InChI: InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChIKey: NOWKCMXCCJGMRR-UHFFFAOYSA-N
SMILES: C1NC1
LogP: -0.969 (est)

Indirect Additives used in Food Contact Substances: POLYETHYLENIMINE
EWG's Food Scores: 1
EPA Substance Registry System: Aziridine, homopolymer (9002-98-6)
IUPAC Name: aziridine
Molecular Weight: 10,000
Molecular Formula: C2H5N
Canonical SMILES: C1CN1
InChI Key: NOWKCMXCCJGMRR-UHFFFAOYSA-N
Density: 1.029-1.038
EC Number: 205-793-9
Exact Mass: 43.04220
H-Bond Acceptor: 1
H-Bond Donor: 1
UN Number: 1185
Viscosity: 40,000 - 150,000 cps

Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable
Density: 1.030 g/mL at 25 °C
Boiling Point: 250 °C(lit.)
Flash Point: >230 ºF
Melting Point: 59-60 °C
Refractive index: n20D 1.5290
CAS No.: 9002-98-6
Molecular Formula: (C2H5N)x
InChIKeys: InChIKey=NOWKCMXCCJGMRR-UHFFFAOYSA-N
Molecular Weight: 43.069
Exact Mass: 43.04220

EC Number: 205-793-9
HScode: 39019090
Categories: Polymer
PSA: 21.94000
XLogP3: -0.4
Appearance: Pale yellow Liquid
Density: 1.05 g/cm3
Melting Point: 59-60°C
Boiling Point: 250 °C(lit.)
Flash Point: >230 °F
Refractive Index: n20/D 1.5290
Water Solubility: soluble in water.
Storage Conditions: 2-8°C
Vapor Pressure: 9 mmHg ( 20 °C)
Vapor Density: 1.48

Flammability characteristics: Class IB
Explosive limit: Explosive limits , vol% in air: 3.3-55
Odor: Pungent, ammonia-like odor
PH: Strongly alkaline
Name: Polyethyleneimine
EINECS: 205-793-9
CAS No.: 9002-98-6
Density: 1.030 g/mL at 25 °C
PSA: 21.94000
LogP: -0.08160
Solubility: Soluble in water.
Melting Point: 59-60°C
Formula: (C2H5N)x
Boiling Point: 250 °C(lit.)
Molecular Weight: 43.06780
Flash Point: >230 °F
Appearance: N/A



FIRST AID MEASURES of POLYETHYLENIMINE (PEI):
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POLYETHYLENIMINE (PEI):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of POLYETHYLENIMINE (PEI):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYETHYLENIMINE (PEI):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of POLYETHYLENIMINE (PEI):
-Precautions for safe handling:
*Advice on safe handling:
Handle under argon.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection. Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under argon.



STABILITY and REACTIVITY of POLYETHYLENIMINE (PEI):
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


POLYETHYLENIMINES
Polyethylenimines are hydrophilic polymer widely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids.
Polyethylenimines are organic macromolecules with high cationic-charge-density potential.


CAS Number: 9002-98-6
EC Number: 205-793-9
MDL number: MFCD00084427
Linear Formula: H(NHCH2CH2)nNH2
Chemical formula: (C2H5N)n, linear form



SYNONYMS:
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pei-275, p 1000, pei-14m, epomine 1000, pei 1000, lupasol g 20, pei-10, Polyethylenimine (PEI), epomin p 1000, pei 1120, corcat p 150, paz 33, pei-250, epomin sp 103, polyethyleneimine, 50 % solution in water, polymin g 15m, corcat p 18, dow pei-6, lugalvan g 20, polymin 6, ethoxylated polyethylenimine, m.w. 60,000, everamine, lupasol g 35, poly (ethylenimine), 15t, polymin g 500, epomine p 1000, adcote 372, everamine 210t, epomin sp 003, emerlube 6717, polymin, pei 600, pei-45, epomin sp 018, lupasol sk, polyethylenimine, m.w.600, epomin sp 110, pei 2, montrek pei 6, montrek 6, pei 100, pei-15, pei-30, dow pei-600e, lugalvan g 15, montrek 600, epomin sp 006, p 1000 (polyamine), epamine 150t, p 70 (polyamine), cf 218 (polymer), tydex 12, lugalvan g 35, Adcote372MW, Aldrich 408719, Aldrich 482595, Aziridine Polymer, Basocoll PR 8086, Basomin G 500, Basonal White FO 1, Bufloc 595, CF 218, CF 218 (Polymer), CP 8994, Corcat P 100, Corcat P 12, Corcat P 145, Corcat P 150, Corcat P 18, Corcat P 200, Corcat P 600, Duramax 1007, EA 275, EAz 1300, EAz 800, EC 005, EL 402, EL 420, EP 108, EP 108 (Polymer), Emerlube 6717, Epomin, Epomin 018, Epomin 1000, Epomin 1050, Epomin 150T, Epomin D 3000, Epomin HM 2000, Epomin L 18, Epomin P 003, Epomin P 012, Epomin P 1000, Epomin P 1030, Epomin P 1050, Epomin P 1500, Epomin P 200, Epomin P 500, Epomin S 1000, Epomin S 300, Epomin SP 003, Epomin SP 006, Epomin SP 012, Epomin SP 012D, Epomin SP 018, Epomin SP 030, Epomin SP 050, Epomin SP 075, Epomin SP 1000, Epomin SP 103, Epomin SP 110, Epomin SP 12, Epomin SP 200, Epomin SP 300, Ethyleneimine Homopolymer, Ethylenimine Homopolymer, Everamine, Everamine 150T, Everamine 210T, Everamine 500T, Everamine 50T, F 2S, FC, Fluka P 3142, G 100, G 20, G 20WF, G 35, G 500, HF, HG 20, HM 2000, HZ 20, HZ 20 (Polyamine), IP 232, JS 980, K 203C, Katax 6760, L 771, Liposol G, Loxanol MI 6730, Loxanol MI 6735, Lugalvan G 15, Lugalvan G 20, Lugalvan G 35, Lugalvan G 50, Lupasol 800, Lupasol 8515, 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Polyethylenimines are polymer with repeating units composed of ethylene diamine groups.
Polyethylenimines contain primary, secondary and tertiary amino groups.
Polyethylenimines are hydrophilic polymer widely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids.


Polyethylenimines are high-charge cationic polymer that readily binds highly anionic substrates.
Industrially, linear Polyethylenimines can improve the appearance of negatively charged dyes by modulating their properties and improving their adherence to surfaces.


Polyethylenimines are organic macromolecules with high cationic-charge-density potential.
Polyethylenimines can ensnare DNA as well as attach to cell membrane, PEI also retains a substantial buffering capacity at virtually any pH.
A significant advantage of Polyethylenimines lies in their superior transfection efficiency, surpassing many conventional methods.


Polyethylenimines's capacity to surmount cellular barriers and directly deliver genetic material to the nucleus ensures robust and dependable gene expression, catering to a wide spectrum of research needs spanning from fundamental inquiries to therapeutic interventions.
Moreover, Polyethylenimines provide researchers with extensive flexibility in experimental design, allowing for precise adjustments of transfection parameters to achieve optimal outcomes.


This versatility empowers scientists to explore diverse avenues in gene function studies, protein expression analyses, and gene therapy investigations, unleashing new possibilities in molecular biology and genetic research.
Polyethylenimines are a biocompatible polymer that can be used in wastewater treatment.


Polyethylenimines are soluble in water and has surfactant properties.
Polyethylenimines are a hydrophilic polymer and a gene carrier, which can be conjugated with dextran to enhance the stability of polycationic vectors.
Polyethylenimines are also used in the preparation of cationic poly(lactic-co-glycolic acid) (PLGA) nanoparticles for potential usage in gene therapy.


Polyethylenimines can also be grafted on polyacrylonitrile (PAN) fiber membrane for the removal of hexavalent chromium (VI) from wastewater.
Polyethylenimines are pale yellow viscous liquid with an amine-like odor.
Polyethylenimines are highly basic and positively charged aliphatic polymers, containing primary, secondary and tertiary amino groups in a 1:2:1 ratio.


Every third atom of the polymeric backbone is therefore an amino nitrogen that may undergo protonation.
As the polymer contains repeating units of ethylamine, Polyethylenimines are also highly watersoluble.
Polyethylenimines are available in both linear and branched forms with molecular weights ranging from 700 Da to 1000 kDa.



USES and APPLICATIONS of POLYETHYLENIMINES:
Polyethylenimines are used stable in combination with other positively charged particles.
Polyethylenimines are used layer by layer construction of nanoparticle surfaces.
Polyethylenimines are used binding to negatively charged substrates or larger particles.


Polyethylenimines are used color engineering.
Polyethylenimines are used the degree of polymerization used in the paper industry is about 1 00.
Polyethylenimines have high reaction activity, can react with the hydroxyl group in cellulose and cross-linking polymerization, so that the wet strength of the paper.


Polyethylenimines are used the presence of any acid, base, and aluminum sulfate will affect the wet strength and retention.
Polyethylenimines are used as the wet strength agent of the respiratory paper without sizing, the retention agent and the beating agent in the paper making process can reduce the beating degree of the pulp, improve the dehydration ability of the paper, and speed up the drainage of the pulp, the fine fibers in white water are easy to flocculate.


Polyethylenimines can also be used to treat cellophane, reduce wetting deformation of the paper, etc.
Polyethylenimines can also be used for fiber modification, printing and dyeing auxiliaries, ion exchange resins, etc.
Polyethylenimines have a strong binding force to acid dyes and can be used as a fixing agent for acid dye dyeing paper.


Primary amines on the Polyethylenimines are used to covalently link BPEI to carboxyl functionalized nanoparticles to generate a robust BPEI surface that is highly positively charged.
Polyethylenimines can be used as a precursor to synthesize conjugated polyplexes for efficient gene transfection.


Conjugation of Polyethylenimines with Jeffamine polyether and guanidinylation of the amino groups of PEI reduce the cytotoxicity of the polyplexes and protect them from aggregation in the presence of serum proteins.
Bamboo charcoal impregnated with Polyethylenimines can be used as a CO2 adsorbent.


Numerous amino groups present in Polyethylenimines can react with CO 2 due to acid-alkali interaction and enhance the adsorption capacity of bamboo charcoal.
Polyethylenimines can also be used to prepare cross-linked water-soluble polymers with high coordination capabilities towards organic drug molecules.


Owing to its excellentphysicochemical properties, Polyethylenimines are applied in many fields like the separation and purification of proteins, carbon dioxide absorption, drug carriers, effective treatment, and biological labels.
Polyethylenimines are widely used as transfection reagent.


Polyethylenimines, a cationic polymer, have revolutionized the field of transfection with their exceptional efficiency and adaptability.
Polyethylenimines unique capability to create stable complexes with nucleic acids enables the effective transfer of DNA, RNA, and proteins into various cell types, including those historically challenging to transfect.


Polyethylenimines are widely used in many applications due to their polycationic character.
Unlike its linear equivalent, branched Polyethylenimines contain primary, secondary, and tertiary amines.
Primarily utilized in industrial applications, high molecular weight Polyethylenimines have been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture.


Polyethylenimines are used Strongly cationic polymer that binds to certain proteins.
Polyethylenimines are used as a marker in immunology, to precipitate and purify enzymes and lipids
Polyethylenimines have been shown to have receptor activity and can be used as a model system for studying the effects of polymers on living cells.


Polyethylenimines may also be used as an adjuvant to increase the efficacy of other drugs or as a means of drug delivery.
Polyethylenimines also have some glycol ethers, which can help prevent it from being degraded by hydrogen fluoride.
For a long time, Polyethylenimines have been also used in non-pharmaceutical processes, including water purification, paper and shampoo manufacturing.


It has been also reported that Polyethylenimines are relatively safe for internal use in animals and humans.
Polyethylenimines are widely used to flocculate cellular contaminants, nucleic acids, lipids and debris from cellular homogenates to facilitate purification of soluble proteins.


Enzymatic reactions in bioprocesses constitute another field in which Polyethylenimines were used: as an immobilizing agent for biocatalysts, as a soluble carrier of enzymes or in the formation of macrocyclic metal complexes mimicking metalloenzymes.
Polyethylenimines are also a common ingredient in a variety of formulations ranging from washing agents to packaging materials.


Polyethylenimines have been extensively studied as a vehicle for nonviral gene delivery and therapy.
Since its introduction in 1995, Polyethylenimines have been considered the gold standard for polymer-based gene carriers because of the excellent transfection efficiencies of its polyplexes (complex of nucleic acid and polymer) in both in vitro and in vivo models.


Polycation-mediated gene delivery is based on electrostatic interactions between the positively charged polymer and the negatively charged phosphate groups of DNA.
In aqueous solution, Polyethylenimines condense DNA and the resulting PEI/DNA complexes, carrying a net positive surface charge, can interact with the negatively charged cell membrane and readily internalized into cells.


Polyethylenimines retain a substantial buffer capacity at virtually any pH and it has been hypothesized that this simple molecular property is related to the efficiency of the complex multistage process of transfection.
As a matter of fact, the ‘proton sponge’ nature of Polyethylenimines are thought to lead to buffering inside endosomes.


The proton influx into the endosome, along with that of counter-anions (generally chloride anions), maintains the overall charge neutrality even if an increase of ionic strength inside the endosome is expected.


This effect generates an osmotic swelling and the consequent physical rupture of the endosome, resulting in the escape of the vector from the degradative lysosomal compartment.
The proton sponge hypothesis has been a subject of debate, speculation and research without reaching a general consensus about the real mechanism involved.


Use of Polyethylenimines for delivery of small drugs, and for the photodynamic therapy (PDT)
As polycation, Polyethylenimines were selected for its several advantageous properties (hydrophylicity, biocompatibility and thermal stability) and furosemide was chosen as a model water-insoluble drug.


The furosemide-loaded calcium alginate (ALG), calcium alginatepolyethyleneimine (ALG-PEI) and alginate-coated ALG-Polyethylenimines (ALG-PEI-ALG) beads by ionotropic/polyelectrolyte complexation method to achieve controlled release of the drug were prepared.
Release of furosemide from ALG-Polyethylenimines beads was prolonged considerably compared with that from ALG beads.


Ionic interaction between alginate and Polyethylenimines led to the formation of polyelectrolyte complex membrane, the thickness of which was dependent on the conditions of PEI treatment (PEI concentration and exposure time).
The membrane acted as a physical barrier to drug release from ALG-Polyethylenimines beads.


The coating of ALG-Polyethylenimines beads further prolonged the release of the drug by increasing membrane thickness and reducing swelling of the beads possibly by blocking the surface pores.
Hamblin’s research group has been involved in the use of photodynamic therapy (PDT) as a possible treatment for localized infections.


They shown that covalent conjugates between Polyethylenimines and chlorin (e6) (ce6) can be used as a potent broad-spectrum antimicrobial photo sensitizers (PS) resistant to protease degradation and therefore constituting an alternative to the previously described poly-L-lysine chlorin (e6) (pL-ce6) conjugates.



FEATURES OF POLYETHYLENIMINES:
Polyethylenimines are one of the most widely used synthetic polycations in various applications because of its chemical functionality arising from the presence of cationic primary (25%), secondary (50%), and tertiary amines (25%).

Polyethylenimines are formed by the linking of iminoethylene units and can have linear, branched, comb, network, and dendrimer architectures depending upon its synthesis and modification methods, which greatly influences its properties, both physical and chemical.

Furthermore, these synthetic approaches enable Polyethylenimines to be available in a wide range of molecular weights.
At room temperature, branched Polyethylenimines are a highly viscous liquid while linear PEI (LPEI) is a solid.

Polyethylenimines have several attractive features for its use in widespread applications, such as low toxicity, ease of separation and recycling, and (last but not least) it being odorless.

In addition to these attractive features, there is a distinct feature of Polyethylenimines which places it ahead of other polyions (e.g. polyallylamine or chitosan) when it comes to loading, and which justifies its widespread use in fields as varied as detergents, adhesives, water treatment, cosmetics, carbon dioxide capture, as a DNA transfection agent, and in drug delivery despite being a weak polymeric base with pKa values between 7.9 and 9.6, it possesses a high ionic charge density, which in practical terms translates into being a more cost-effective material.

This derives from the possibility of either reaching the same loadings with reduced amounts of the polymer (which would colloquially mean "getting a bigger bang for the buck") or reaching loadings that are beyond the reach of the aforementioned examples while avoiding enzyme agglomeration thanks to its multi-branched network.



PHYSICAL AND CHEMICAL PROPERTIES OF POLYETHYLENIMINES:
*Polyethylenimines are a colorless and highly viscous liquid.
*Polyethylenimines are soluble in water, ethanol, hygroscopic, insoluble in benzene and acetone.
*Polyethylenimines will produce precipitation when it meets sulfuric acid with pH below 2.4.
*The aqueous solution of Polyethylenimines is positively charged, and formaldehyde is added to produce condensation.
*Polyethylenimines are colorless or light yellow viscous liquid, hygroscopic, soluble in water, ethanol, insoluble in benzene, acetone.
*Precipitation occurs when it meets sulfuric acid with a pH of less than 2.4.
*The aqueous solution was positive and formaldehyde was added to produce coagulation.
*Gelation occurs in the presence of an acid.
*Commercially available products are generally aqueous solutions having a concentration of 20% to 50%.



ADVANTAGES OF POLYETHYLENIMINES:
*Strongly positively charged surface (cationic)



PROPERTY HIDHLIGHTS OF POLYETHYLENIMINES:
*Isoelectric Point: ~11
*Displaceable: Not displaceable – strongly bound to the particle surface
*Positively charged
*Good salt stability: stable in highly saline solutions



PREPARATION METHOD OF POLYETHYLENIMINES:
first, ethyleneimine was obtained by esterification of ethanolamine with sulfuric acid.
The ethyleneimine may be further polymerized under acidic conditions.



PHYSICAL and CHEMICAL PROPERTIES of POLYETHYLENIMINES:
Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable
Melting Point: 59-60°C
Boiling Point: 250 °C(lit.)
Flash Point: >230 °F
Molecular Formula: C2H5N
Molecular Weight: 43.06780
Density: 1.030 g/mL at 25 °C
Physical state: viscous
Color: colorless
Odor: No data available
Melting point/freezing point
Melting point/range: 54 - 59 °C
Initial boiling point and boiling range: 250 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point: > 110 °C - closed cup
Autoignition temperature: > 200 °C
Decomposition temperature: > 250 °C
pH: 11 - DIN 19268
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 15.000 mPa.s at 50 °C
Water solubility soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: 1,030 g/cm3 at 25 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available

Fòrmula: (C2H5N)x
No. CAS: 9002-98-6
Appearance: Liquid
Color: Colorless to light yellow
SMILES: NCCN(CCN)CCN(CCCNCN)CCN(CCNCCN)CCNCCN(CCN)CCN.[n]
Appearance (Form): Viscous Liquid
Refractive index: n20/D 1.5290
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C
Impurities: ≤1% water
CBNumber: CB9162514
Molecular Formula:C2H5N
Molecular Weight:43.07
MDL Number:MFCD00803910
MOL File:9002-98-6.mol
Melting point: 59-60°C
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C

vapor pressure: 9 mmHg ( 20 °C)
refractive index: n20/D 1.5290
Flash point: >230 °F
storage temp.: 2-8°C
solubility: DMSO (Sparingly)
form: Liquid
color: Pale yellow
Specific Gravity: 1.045 (20/4℃)
PH: pH(50g/l, 25℃) : 10~12
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
InChI: InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChIKey: NOWKCMXCCJGMRR-UHFFFAOYSA-N
SMILES: C1NC1
LogP: -0.969 (est)

Indirect Additives used in Food Contact Substances: POLYETHYLENIMINE
EWG's Food Scores: 1
EPA Substance Registry System: Aziridine, homopolymer (9002-98-6)
IUPAC Name: aziridine
Molecular Weight: 10,000
Molecular Formula: C2H5N
Canonical SMILES: C1CN1
InChI Key: NOWKCMXCCJGMRR-UHFFFAOYSA-N
Density: 1.029-1.038
EC Number: 205-793-9
Exact Mass: 43.04220
H-Bond Acceptor: 1
H-Bond Donor: 1
UN Number: 1185
Viscosity: 40,000 - 150,000 cps

Chemical formula: (C2H5N)n, linear form
Molar mass: 43.04 (repeat unit), mass of polymer variable
Density: 1.030 g/mL at 25 °C
Boiling Point: 250 °C(lit.)
Flash Point: >230 ºF
Melting Point: 59-60 °C
Refractive index: n20D 1.5290
CAS No.: 9002-98-6
Molecular Formula: (C2H5N)x
InChIKeys: InChIKey=NOWKCMXCCJGMRR-UHFFFAOYSA-N
Molecular Weight: 43.069
Exact Mass: 43.04220

EC Number: 205-793-9
HScode: 39019090
Categories: Polymer
PSA: 21.94000
XLogP3: -0.4
Appearance: Pale yellow Liquid
Density: 1.05 g/cm3
Melting Point: 59-60°C
Boiling Point: 250 °C(lit.)
Flash Point: >230 °F
Refractive Index: n20/D 1.5290
Water Solubility: soluble in water.
Storage Conditions: 2-8°C
Vapor Pressure: 9 mmHg ( 20 °C)
Vapor Density: 1.48

Flammability characteristics: Class IB
Explosive limit: Explosive limits , vol% in air: 3.3-55
Odor: Pungent, ammonia-like odor
PH: Strongly alkaline
Name: Polyethyleneimine
EINECS: 205-793-9
CAS No.: 9002-98-6
Density: 1.030 g/mL at 25 °C
PSA: 21.94000
LogP: -0.08160
Solubility: Soluble in water.
Melting Point: 59-60°C
Formula: (C2H5N)x

Boiling Point: 250 °C(lit.)
Molecular Weight: 43.06780
Flash Point: >230 °F
Appearance: N/A
CAS: 9002-98-6
EINECS: 618-346-1
InChI: InChI=1/C2H5N/c1-2-3-1/h3H,1-2H2
Molecular Formula: C2H5N
Molar Mass: 43.07
Density: 1.030 g/mL at 25°C
Melting Point: 59-60°C
Boiling Point: 250°C (lit.)
Flash Point: >230°F
Water Solubility: Soluble in water.

Vapor Pressure: 9 mmHg (20°C)
Appearance: Liquid
Specific Gravity: 1.045 (20/4°C)
Color: Pale yellow
pH: pH (50g/l, 25°C): 10-12
Storage Condition: 2-8°C
Sensitive: Hygroscopic
Refractive Index: n20/D 1.5290
Additional Information:
CBNumber: CB5499238
Molecular Formula (Polymer): C4H13N3
Molecular Weight (Polymer): 103.17
MDL Number (Polymer): MFCD00084427

Density (Polymer): 1.08 g/mL at 25°C
Vapor Pressure (Polymer): 9 mmHg (20°C)
Refractive Index (Polymer): n20/D 1.5240
Flash Point (Polymer): >230°F
Solubility (Polymer): Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
Form (Polymer): Oil
Color (Polymer): Colorless
InChI (Polymer): InChI=1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2
InChIKey (Polymer): SFLOAOINZSFFAE-UHFFFAOYSA-N
SMILES (Polymer): C(N)CN.C1NC1
FDA 21 CFR: 175.105; 175.320; 177.1200
EPA Substance Registry System: 1,2-Ethanediamine, polymer with aziridine (25987-06-8)



FIRST AID MEASURES of POLYETHYLENIMINES:
-Description of first-aid measures:
*General advice
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POLYETHYLENIMINES:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent and neutralising material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of POLYETHYLENIMINES:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYETHYLENIMINES:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
required
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type ABEK
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of POLYETHYLENIMINES:
-Precautions for safe handling:
*Advice on safe handling:
Handle under argon.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection. Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Store under argon.



STABILITY and REACTIVITY of POLYETHYLENIMINES:
-Reactivity:
No data available
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


POLYETHYLENIMINES
Polyethylenimines or polyaziridine is a polymer with repeating units composed of the amine group and two carbon aliphatic CH2CH2 spacers.
Linear polyethyleneimines contain all secondary amines, in contrast to branched PEIs which contain primary, secondary and tertiary amino groups.
Totally branched, dendrimeric forms were also reported.

CAS: 9002-98-6
MF: C2H5N
MW: 43.07
EINECS: 618-346-1

Synonyms
POLYETHYLENEIMINE, BRANCHED;Aziridine,homopolymer;Ethyleneimine,homopolymer;polyethylenimine(10,000);polyethylenimine(20,000);PEI-1750;PEI-2500;ETHYLENE IMINE POLYMER SOLUTION, 50% IN WATER

Polyethylenimines is produced on an industrial scale and finds many applications usually derived from its polycationic character.
Polyethylenimines, an organic polyamine polymer, is one of the most prominent examples of cationic polymers capable of gene transfection in vitro and in vivo into various cell lines and tissues.
Polyethylenimines was also applied in different fields from gene therapy and several studies have emphasized the importance of this polymer in medicinal chemistry.
Polyethylenimines is a saturated organic heteromonocyclic parent, a member of aziridines and an azacycloalkane.
Polyethylenimines has a role as an alkylating agent.
Polyethylenimines is a conjugate base of an aziridinium.

All Polyethylenimines imine polymers are hydrophilic and may contain approx.
30% hydrated water.
Polyethylenimines exists as both a branched and linear structure.
Branched PEI (bPEI) is synthesized via acid-catalyzed polymerization of aziridine, whereas the linear structure (lPEI) is synthesized via ring opening polymerization of 2-ethyl-2-oxazoline followed by hydrolysis.
Polyethylenimines, a cationic polymer, has revolutionized the field of transfection with its exceptional efficiency and adaptability.
Polyethylenimines's unique capability to create stable complexes with nucleic acids enables the effective transfer of DNA, RNA, and proteins into various cell types, including those historically challenging to transfect.

Polyethylenimines is a water-soluble polymer that has been used in the treatment of bowel disease.
Polyethylenimines has a receptor activity and can be used as a surfactant, which is an agent that reduces surface tension.
Polyethylenimines can also be used as a polymer with a pyrazole ring, which is an aromatic heterocycle containing two nitrogen atoms and two carbon atoms.
Polyethyleneimines has been shown to have biochemical properties such as being biocompatible and exhibiting antifungal properties.
Polyethyleneimines can be synthesized by reacting ethyleneimine and aziridine.
Polyethylenimines are biocompatible, water-soluble, and can be synthesized using ethyleneimine and aziridine.
Polyethyleneimine's synthesis involves reacting ethyleneimine with aziridine to form the imine intermediate followed by hydrolysis of the imine to form polyethyleneimine.

Polyethylenimines Chemical Properties
Melting point: 59-60°C
Boiling point: 250 °C(lit.)
Density: 1.030 g/mL at 25 °C
Vapor pressure: 9 mmHg ( 20 °C)
Refractive index: n20/D 1.5290
Fp: >230 °F
Storage temp.: 2-8°C
Solubility: DMSO (Sparingly)
Form: Liquid
Color: Pale yellow
Specific Gravity: 1.045 (20/4℃)
PH:pH(50g/l, 25℃) : 10~12
Water Solubility: Soluble in water.
Sensitive: Hygroscopic
InChI: InChI=1S/C2H5N/c1-2-3-1/h3H,1-2H2
InChIKey: NOWKCMXCCJGMRR-UHFFFAOYSA-N
LogP: -0.969 (est)
EPA Substance Registry System: Polyethylenimines (9002-98-6)

The linear Polyethylenimines is a semi-crystalline solid at room temperature while branched PEI is a fully amorphous polymer existing as a liquid at all molecular weights.
Linear Polyethylenimines is soluble in hot water, at low pH, in methanol, ethanol, or chloroform.
Polyethylenimines is insoluble in cold water, benzene, ethyl ether, and acetone.
Linear Polyethylenimines has a melting point of around 67 °C.
Both linear and branched polyethyleneimine can be stored at room temperature.
Linear polyethyleneimines is able to form cryogels upon freezing and subsequent thawing of its aqueous solutions.

Uses
Polyethyleneimines acts as a protein precipitant used to purify proteins.
Polyethylenimines is used as a chelating agent and as a scavenger for aldehydes and oxides.
Polyethylenimines is also used in detergents, paper industry, dyes, printing inks and in water treatment.
Branched polyethyleneimines is widely used in many applications due to its polycationic character.
Unlike its linear equivalent, branched Polyethylenimines contains primary, secondary, and tertiary amines.
Primarily utilized in industrial applications, high molecular weight Polyethylenimines has been used as a flocculating agent, textile coating, adhesion promoter, enzyme carrier, and as a material for CO2 capture.
Polyethylenimines is used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.

Polyethylenimines can be used as a non-viral synthetic polymer carrier for in vivo delivery of therapeutic nucleic acids.
The interaction between the negatively charged nucleic acid and the positively charged polymer backbone leads to the formation of nanoscale complexes.
This neutralising complex protects the enclosed nucleic acid from enzymes and maintains its stability until cellular uptake occurs.
For example, human serum albumin-coupled Polyethylenimines shows good pDNA transfection and low toxicity.
Polyethylenimines can be used to functionalize single-walled nanotubes (SWNTs) to improve their solubility and biocompatibility while maintaining the structural integrity of the original SWNT.
Covalently functionalized SWNTs can be used for CO2 uptake and gene delivery.
Branched Polyethylenimines can also be used to modify the surface properties of adsorbents.
Polyethylenimines-modified aqueous zirconia/PAN nanofibres have a high fluoride adsorption capacity and a wide working pH range, and can therefore be used for groundwater defluoridation.

Polyethyleneimines finds many applications in products like: detergents, adhesives, water treatment agents and cosmetics.
Owing to its ability to modify the surface of cellulose fibres, Polyethylenimines is employed as a wet-strength agent in the paper-making process.
Polyethylenimines is also used as flocculating agent with silica sols and as a chelating agent with the ability to complex metal ions such as zinc and zirconium.
There are also other highly specialized PEI applications:

Biology
Polyethylenimines has a number of uses in laboratory biology, especially tissue culture, but is also toxic to cells if used in excess.
Toxicity is by two different mechanisms, the disruption of the cell membrane leading to necrotic cell death (immediate) and disruption of the mitochondrial membrane after internalisation leading to apoptosis (delayed).

Attachment promoter
Polyethyleneimines are used in the cell culture of weakly anchoring cells to increase attachment.
Polyethylenimines is a cationic polymer; the negatively charged outer surfaces of cells are attracted to dishes coated in PEI, facilitating stronger attachments between the cells and the plate.

Transfection reagent
Polyethylenimines was the second polymeric transfection agent discovered, after poly-L-lysine.
PEI condenses DNA into positively charged particles, which bind to anionic cell surface residues and are brought into the cell via endocytosis.
Once inside the cell, protonation of the amines results in an influx of counter-ions and a lowering of the osmotic potential.
Osmotic swelling results and bursts the vesicle releasing the polymer-DNA complex (polyplex) into the cytoplasm.
If the polyplex unpacks then the DNA is free to diffuse to the nucleus.

Permeabilization of gram negative bacteria
Polyethylenimines is also an effective permeabilizer of the outer membrane of Gram-negative bacteria.

CO2 capture
Both linear and branched polyethylenimine have been used for CO2 capture, frequently impregnated over porous materials.
First use of Polyethylenimines polymer in CO2 capture was devoted to improve the CO2 removal in space craft applications, impregnated over a polymeric matrix.
After that, the support was changed to MCM-41, an hexagonal mesostructured silica, and large amounts of Polyethylenimines were retained in the so-called "molecular basket".
MCM-41-Polyethylenimines adsorbent materials led to higher CO2 adsorption capacities than bulk PEI or MCM-41 material individually considered.
The authors claim that, in this case, a synergic effect takes place due to the high Polyethylenimines dispersion inside the pore structure of the material.
As a result of this improvement, further works were developed to study more in depth the behaviour of these materials.

Exhaustive works have been focused on the CO2 adsorption capacity as well as the CO2/O2 and CO2/N2 adsorption selectivity of several MCM-41-PEI materials with PEI polymers.
Also, Polyethylenimines impregnation has been tested over different supports such as a glass fiber matrix and monoliths.
However, for an appropriate performance under real conditions in post-combustion capture (mild temperatures between 45-75 °C and the presence of moisture) it is necessary to use thermally and hydrothermally stable silica materials, such as SBA-15, which also presents an hexagonal mesostructure.
Moisture and real world conditions have also been tested when using PEI-impregnated materials to adsorb CO2 from the air.

Production Methods
Polyethylenimines is produced by the homopolymerization of ethylenimine.
The reaction is catalyzed by acids, Lewisacids, or haloalkanes.
The polymerization is usually carried out at 90 – 110 ℃ in water or in a variety of organic solvents.
The average molecular mass of the polyethylenimine prepared as described above is 10 000 – 20 000.
Higher molecular mass polymers are prepared by addition of a difunctional alkylating agent, such as chloromethyloxirane or 1,2-dichloroethane.
Polyethylenimines with a higher average molecular mass can also be provided by ultrafiltration of polymers with a broad mass distribution.
Likewise, polymers of lower molecular mass can be obtained by inclusion of a low molecular mass amine, such as 1,2- ethanediamine, during polymerization.
By using these techniques a range of molecular masses from 300 to 10 6 can be obtained.
Cross-linking during the polymerization of ethylenimine in organic solvents leads to solid polyethylenimines.
Furthermore the polymerization process can be conducted on the surface of organic or inorganic materials, thus fixing the polyethylenimines to a support.

Biological Activity
Polyethylenimines are nondegradable and the molecular weight of PEI affects the cytotoxicity and gene transfer activity.
Polyethylenimines acts as a low toxicity and efficient gene vector.

Synthesis
Branched Polyethylenimines can be synthesized by the ring opening polymerization of aziridine.
Depending on the reaction conditions different degree of branching can be achieved.
Linear Polyethylenimines is available by post-modification of other polymers like poly(2-oxazolines) or N-substituted polyaziridines.
Linear Polyethylenimines was synthesised by the hydrolysis of poly(2-ethyl-2-oxazoline) and sold as jetPEI.
The current generation in-vivo-jetPEI uses bespoke poly(2-ethyl-2-oxazoline) polymers as precursors.
POLYGLUCURONIC ACID
POLYGLUTAMIC ACID, N° CAS : 25513-46-6. Nom INCI : POLYGLUTAMIC ACID. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI).Agent d'entretien de la peau : Maintient la peau en bon état
POLYGLYCERIN-10
POLYGLYCERIN-20, N° CAS : 25618-55-7. Nom INCI : POLYGLYCERIN-20. Ses fonctions (INCI) : Antimicrobien : Aide à ralentir la croissance de micro-organismes sur la peau et s'oppose au développement des microbes. Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau
POLYGLYCERIN-20
POLYGLYCERIN-3, N° CAS : 56090-54-1, Nom INCI : POLYGLYCERIN-3. Nom chimique : Triglycerol. N° EINECS/ELINCS : 259-986-8. Compatible Bio (Référentiel COSMOS) : Ses fonctions (INCI): Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau
POLYGLYCERIN-3
POLYGLYCERIN-6, N° CAS : 36675-34-0. Nom INCI : POLYGLYCERIN-6. Nom chimique : Hexaglycerol. N° EINECS/ELINCS : 253-154-8. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI). Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau
POLYGLYCERIN-6
POLYGLYCERYL-10 CAPRYLATE, N° CAS : 51033-41-1. Nom INCI : POLYGLYCERYL-10 CAPRYLATE. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI) : Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)
POLYGLYCEROL ESTER
Polyglycerol esters are used in food as an emulsifier.
Polyglycerol esters are a class of synthetic, nonionic surfactant frequently used in food, pharmaceutical, and cosmetic industries on account of their amphiphilic properties.
The hydrophilic part of these amphiphiles consists of oligomeric esters of glycerol, and the hydrophobic part consists of alkyl chains of varying length and degree of unsaturation.

CAS: 67784-82-1
MF: (C3H8O3
EINECS: 211-708-6

Synonyms
Polyglycerol Esters of Fatty Acids (PGE);Polyglycerol fatty acid esters;coco;esters with cottonseed-oil fatty acids;polyglycerol and soya fatty acids;Fatty acids, coco, esters with cottonseed-oil fatty acids, polyglycerol and soya fatty acids;Decaglyceryl Dipalmitate;Polyaldo(R) HGMP KFG;Fatty acids, coco, esters with cottonseed-oil fatty acids, polyglycerol and soya fatty acids;67784-82-1;614-133-2;C12, C16, C18 and C18. 1, acid esters of hexaglycerol;DTXSID6095904 ;Polyglycerol esters of cottonseed fatty acids, soybean fatty acids and coconut fatty acids

In foods, they are used as emulsifying agents in the production of baked goods, chewing gum, and in replacement of fats.
Polyglycerol ester can be powder, solid or mucus, its color is white to yellow.
Polyglycerol ester has low water sensitivity, good thermal stability and good acid and salt resistance.
The higher the degree of polymerization of polyglycerol, the shorter the fatty acid chain length, the lower the degree of esterification, the better the hydrophilicity, and vice versa the stronger the lipophilicity.
Generally, the HLB value of polyglyceride is 2-16.
Polyglycerol ester is a type of dietary supplement made from glycerol and fatty acids.
Polyglycerol ester is used to improve the texture and flavor of food, as well as to provide a source of energy.
Polyglycerol ester is also used as an emulsifier and stabilizer in food products.

Polyglycerol esters have been found to have a number of health benefits, including improved digestion, increased absorption of fat-soluble vitamins, improved cholesterol levels, and improved blood sugar levels.
Additionally, polyglycerol esters have been found to have anti-inflammatory properties, which can help reduce the risk of certain diseases.
Finally, polyglycerol esters have been found to have antioxidant properties, which can help protect the body from damage caused by free radicals.

The potential dangers of taking a polyglycerol ester dietary supplement include an increased risk of gastrointestinal distress, such as nausea, vomiting, and diarrhea.
Polyglycerol ester may also cause an allergic reaction in some people, resulting in skin rashes, itching, and difficulty breathing.
Additionally, Polyglycerol ester may interact with certain medications, such as blood thinners, and can cause an increased risk of bleeding.
Polyglycerol ester is important to speak with a doctor before taking any dietary supplement to ensure it is safe for you.

Straw yellow powder or granular solid which is easily soluble in oils and fats and soluble in organic solvents such as ethanol.
Polyglycerol ester can be dispersed in hot water.
Polyglycerol ester's an non-ionic surfactant with characteristics such as high temperature and acid resistance and HLB value is 7.2.
Polyglycerol ester is a non - ionic emulsifier, HLB value 8-10. With a high degree of safety, its biggest characteristic is in the alkaline, neutral, acidic environment is quite stable, compared with similar products with better high temperature resistance, in the high salt content also has a good emulsification performance; Colorless, tasteless, odorless, not easy to hydrolysis, no adverse effects on the appearance and smell of cosmetics; Polyglycerol ester has a very good synergistic effect.
Two or more kinds of polyglycerol fatty acid esters will produce better effects when used in combination.
Polyglycerol ester has strong emulsifying ability and less dosage.

Uses
Polyglycerol esters are used as a dietary supplement to improve the texture and flavor of food products, such as baked goods, dairy products, and sauces.
They are also used as emulsifiers and stabilizers in a variety of food products.
Polyglycerol esters are used in the food industry as an emulsifier, stabilizer, and thickener.
They are used to improve the texture and shelf life of processed foods, such as margarine, ice cream, and salad dressings.
They are also used to improve the texture of baked goods, such as cakes and cookies.

Polyglycerol ester is a kind of hydrophilic monoglyceride, and it can produce strong emulsification effect for oils and fats.
1. Polyglycerol ester can be used in margarine, butter, shortening oil and oyster sauce as emulsifier and crystal modifying additive to prevent oil-water separation and prolong the preservation period.
2 Polyglycerol ester can be used in food baking to make oils an fats dispersed more homogeneously in dough to get higher foamability and produce larger volume of product, fine and supple feeling in mouth.
3. Polyglycerol ester can be added into ice cream to make all components mixed more homogeneous, prevent forming of big ice crystal, help produce fine and dense pore structure, enhance its expansion ratio and produce smooth and fine feeling in mouth.

4. Polyglycerol ester can be used in milk beverage as emulsifier, wetting agent, cosolvent and so on.
Polyglycerol ester can also enhance flavor, aroma and color of them.
5. Polyglycerol ester can be used in meat products to prevent starch aging, shrinkage, water absorption and hardening.
6. Polyglycerol ester can be used in candies and chocolates to prevent oil-water separation and maintain a good taste.

Polyglycerol ester is used as a polysorbate replacer and a crystal inhibitor.
Polyglycerol ester is also a unique bland-tasting food surfactant with minimal restrictions on use level or application.
Polyglycerol ester is used as a polysorbate 60 replacement.

An important application of Polyglycerol ester is in cake batters with little or no content of fat and oil (i.e. batters for sponge cakes, Swiss rolls and similar types of cake formulations that are based on egg, sugar and flour and/or starch).
Polyglycerol ester enhance aeration and help stabilize foams.
The use of Polyglycerol ester makes it possible to produce sponge cakes by single stage mixing, and produce final products with a finer crumb structure and longer shelf life.

Polyglycerol ester can be used in margarines.
The addition of Polyglycerol ester improve the functional properties of the margarine (e.g. the organoleptic properties of spreads, stabilizing or aerating of food) in addition to the emulsification of the emulsion.
Polyglycerol ester are reported to improve the organolepic properties of a margarine or low-fat spread by reducing the graininess of the lipid phase to yield a plasticity and elasticity of the margarine corresponding to natural butter.

Compared to alternative emulsifiers, such as monoglycerides, the polyglycerol ester is found to have an advantage in providing long-time stability of whipping properties, making the emulsifier an excellent choice for cake mixes.
Polyglycerol ester can also be used as low fat shortening.
They can also form emulsion systems with a high amount water, thus reducing the overall caloric content of a food product.
As the α-tending emulsifier, Polyglycerol ester also have the crumb softening and anti-staling effects and they also help improve cake volume in baked products.
The reason is that emulsifiers can reduce the rate of starch retrogradation.

Polyglycerol ester can be used in whippable emulsions and toppings.
They can promote fat particle aggregation and water absorption, and help achieve increased viscosity and aeration, and reduced coalescence.
Different than monoglycerides (MGs), the α-gel structure formed by Polyglycerol esters are thermodynamically more stable, which means the emulsion system formed by PGEs are more stable than that of MGs.
Blends of Polyglycerol ester and MGs are known to improve sponge cake aeration and stability with less mixing time and improved foam and emulsion stability.
POLYGLYCEROL ESTERS
DESCRIPTION:
Polyglycerol esters of fatty acids (PGEs) are used in food as an emulsifier.
Polyglycerol Esters are a class of synthetic, nonionic surfactant frequently used in food, pharmaceutical, and cosmetic industries on account of their amphiphilic properties.
The hydrophilic part of these amphiphiles consists of oligomeric esters of glycerol, and the hydrophobic part consists of alkyl chains of varying length and degree of unsaturation.
In foods, they are used as emulsifying agents in the production of baked goods, chewing gum, and in replacement of fats.

PRODUCT NAME : Polyglycerol Polyricinoleate esters (E476)


SYNONYMS OF POLYGLYCEROL ESTERS:
Glycerin fatty acid esters,Polyglycerol fatty acid esters,PGPR; Condensed castor oil esters , glycerin fatty acids, condensed castor oil fatty acid glycerol esters.



Polyglycerol Esters of Edible Fatty Acids (PGE) is manufactured using polymerized Glycerol and Edible Fatty Acids.
Polyglycerol Esters exists as a white to off-white coloured, oily to hard waxy material.
Polyglycerol Esters is dispersible in water and soluble in oils.

Polyglycerol esters or PGE are a category of nonionic surfactants used in foods.
The properties of the polyglycerol ester will vary with the chain length of the glycerol chain, the number, and types of fatty acids.

Polyglycerol esters have a wide range of functional properties.
Polyglycerol esters are used for whipped toppings, low fat-fat applications, polysorbate 60 replacers, and to improve dry cakes.
Polyglycerol esters will function in low-fat content cakes providing great aeration in cakes that contain little to no fat.

Polyglycerol Esters of Fatty Acids (PGE) is a cream to light yellow powders or beads, that is widely used as an emulsifier in food production.
As a preservative Polyglycerol Esters is used in bread, cake, biscuit and meat product to prevent starch aging and extend shelf life.

As an emulsifier Polyglycerol Esters is used in toffee, chocolate and oil to enhance emusification and increase elasticity and prevent deformation.
As bacteriostatic agents it is used in meat product to inhibit bacteria and extend shelf life.


ORIGIN OF POLYGLYCEROL ESTERS:
PGEs have been used as food additives in Europe and America since the 1940s and they were approved for food use in the U.S. in the 1960s.




COMMERCIAL PRODUCTION OF POLYGLYCEROL ESTERS:
PGEs are produced by polymerization of glycerol in the presence of an alkaline catalyst followed by esterification with fatty acids.
The fatty acids are from corn oil, cottonseed oil, lard, palm oil, peanut oil, sesame oil, sunflower oil, soybean oil, etc.
Besides esters, PGEs also contain impurities, like mono, di, and triglycerides, free fatty acids, free glycerol and polyglycerol, and sodium salts of fatty acids may be present.


FUNCTIONS OF POLYGLYCEROL ESTERS:
Components of bakery products, such as oil, water and flour, are not soluble in each other. Interfaces are present between these substances, such as water and oil, gases (air bubbles) and solid substances (flour components), air and water.
PGEs, like other emulsifiers, have both a hydrophobic and hydrophilic nature so they can reduce interfacial tension between different phases.

PGEs’ hydrophilic-lipophilic balance (HLB) depends on the length of the polyglycerol chain and the degree of esterification.
The HLB can vary from 3 to 14, and the desired HLB value may be obtained by appropriate blending. Depending upon their HLB, PGEs can act as water-in-oil (W/O) or oil-in-water (O/W) emulsifiers.

PGEs form highly stable alpha-gel in water.
The α-gel phase of PGEs is surface active and is able to stabilize foams when the temperature is lower than the melting temperature of the emulsifier.
The special structure also leads to better emulsification properties.


APPLICATIONS OF POLYGLYCEROL ESTERS:
An important application of PGEs is in cake batters with little or no content of fat and oil (i.e. batters for sponge cakes, Swiss rolls and similar types of cake formulations that are based on egg, sugar and flour and/or starch). PGEs enhance aeration and help stabilize foams.
The use of PGEs makes it possible to produce sponge cakes by single stage mixing, and produce final products with a finer crumb structure and longer shelf life.

PGEs can be used in margarines.
The addition of PGEs improve the functional properties of the margarine (e.g. the organoleptic properties of spreads, stabilizing or aerating of food) in addition to the emulsification of the emulsion.

PGE is a Palm-oil free essential emulsifier used in cakes batters, cake gels and non-dairy whipped topping. It also plays a key role in the production of margarine and low-fat spreads.
Additionally, it qualifies as a good food additive for Kosher as well as Halal food preparations.

Functionality:
PGE is used mostly for its aeration and softening ability in cake- based products.
Benefits in Cake Gels:
In cake gels Polyglycerol Esters works synergistically with distilled monoglycerides.
As Polyglycerol Esters is an alpha-tending emulsifier it retards the gel from turning white.
Once used in cake batter the PGE provides extra aeration and volume to the batter.


Polyglycerol Esters provides a smooth texture and crumb structure to the cake and additional softness.

Benefits in Non-Dairy/Whipped Topping:
Polyglycerol Esters Provides aeration and increases over-run
Polyglycerol Esters helps to disperse the fat every throughout the mix and provides better whiteness and more uniform creamy texture.
Polyglycerol Esters Provides stiffness to the topping once it is whipped.


Benefits in Margarine:
Polyglycerol Esters Improves functional properties in the form of better organoleptic properties, stabilisation of emulsions, improved aeration.
Polyglycerol Esters Reduces sandiness in the lipid phase and provides plasticity and elasticity that mimics the nature of butter.
In puff pastry margarine PGE improves the spread of fats in lamination culminating in better flakiness and lift of the baked product.


In cake margarine, which is used extensively by the cake making industry, the fat plays an important part in the aeration of batter.
Fat with PGE performs better in reducing batter density and thereby increases volume.
Polyglycerol Esters also stabilises the batter and improves batch to batch uniformity.



Polyglycerol Esters or PGE are a range of ingredients with a wide range of functional properties.
Polysorbate replacer in Flavors
Many consumers want to avoid foods with polysorbate 60.

Polysorbate is a proven safe ingredient with powerful functionality, sometimes it must be replaced with a more consumer-friendly ingredient.
PGE is a perfect choice for this replacement
High HLB ratio polyglycerol esters can function as Polysorbate replacers.
Many liquid flavors use polysorbate 60 to emulsifier the fat-soluble flavor components in the high water flavor.

Polyglycerol esters are the perfect polysorbate replacer for use in flavors.
Typically a 10-1-o grade is used to replace polysorbate in flavors.

Whipped Toppings :
PGE’s are perfect for use in whipped toppings.
The higher HLB ratio will provide fat particle aggregation in the high water environment of whipped toppings.
PGE will provide increased viscosity and reduced coalescence.

Low-Fat Applications :
Low-fat foods frequently use water as a mass volume replacer of the fat content.
PGEs strongly bond to the water creating a strong emulsion that is viscous and fat like.
10-2-P is the perfect grade for replacing fat as 10-20% 10-2-p PGE forms a vicious fat like emulsion.

Improve Dry Cakes with Polyglycerol Esters :
The number one complaint with cakes is dry or crumbly cakes.
These complaints are inter-related and sometimes are actually the same complaint.
The average cake customer does not like a dry cake, a crumbly cake, or a stale cake.

All three of these terms are used by customers to describe the same cake problem and require a similar solution.
Solve your #1 complaint with our 10-2P polyglycerol esters.
Cake bakers have fought this issue for years.

In the past, gums, starches, and corn syrups were used to combat dry cake, stale cake, and crumbly cake.
None of these solutions made a significant difference to the dry or stale cake problem.
Commercial cake mixes make can make great moist cakes, but the cost is sometimes too high for the scratch baker to tolerate.
PGE will function in low-fat content cakes providing great aeration in cakes that contain little to no fat.

INTENDED USAGE:
Polyglycerol Esters serves to produce better quality chocolate reducing cocoa oil quantity in chocolate industry.
Polyglycerol Esters provides easier discharge property eliminating bubble formation and empty holes.
Polyglycerol Esters serves to produce chocolate with desired refirement.
Polyglycerol Esters doesnt have any bad odour.

Polyglycerol Esters has a good thermal stability.
Polyglycerol Esters is suitable to use together with lecithin.
Polyglycerol Esters makes the process easier.

USAGE AREA :
Polyglycerol Esters is used in Chocolate and products thereof
Polyglycerol Esters is used in Low oil content products
Polyglycerol Esters is used in Spreadable oils (oil rate is less than 41%)

Polyglycerol Esters is used in Cocoa based candies
Polyglycerol Esters is used in Spreadable products (oil rate is less than 10%)
Polyglycerol Esters is used in Sauces

Polyglycerol Esters is used in Ice cream mixtures
Polyglycerol Esters is used in Candies
Polyglycerol Esters is used in Drug and cosmetic mixtures
Polyglycerol Esters is used in Oil and water emulsions





CHEMICAL AND PHYSICAL PROPERTIES OF POLYGLYCEROL ESTERS:

EC No., E 475
Form, Oily to hard waxy
Colour, Creamish White
Acid Value, Max 6 mgKOH/gm
Saponification Value, 135-175mgKOH/gm
Iodine Value, Max 3
Total Fatty Acid Ester content, Min 90%
Total Glycerol and Polyglycerol, 18-60%
Heavy Metals (as Pb), Less than 10mg/kg
Arsenic, Less than 3 mg/kg
Cadmium, Less than 1mg/kg
Mercury, Less than 1 mg/kg
CLASS : Emulsifier
DESCRIPTION AND INGREDIENTS : It is a special product obtained by esterification of polyglycerol with condensed castor oil, fatty acids.
APPEARANCE : Clear yellowish liquid.



SAFETY INFORMATION ABOUT POLYGLYCEROL ESTERS:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



POLYGLYCEROL POLYRICINOLEATE (PGPR)
Polyglycerol polyricinoleate (PGPR) can also be used as an emulsifier in spreads and in salad dressings, or to improve the texture of baked goods.
Polyglycerol polyricinoleate (PGPR) is made up of a short chain of glycerol molecules connected by ether bonds, with ricinoleic acid side chains connected by ester bonds.
Polyglycerol polyricinoleate (PGPR) is a yellowish, viscous liquid, and is strongly lipophilic: it is soluble in fats and oils and insoluble in water and ethanol.

CAS Number: 29894-35-7
Molecular Formula: C27H52O9
Molecular Weight: 520.69638

Synonyms: 1,2,3-Propanetriol, homopolymer, 12-(R)-hydroxy-9-(Z)-octadecenoates (1:1) (3 mol glycerol average molar ratio), 29894-35-7, 9-Octadecenoic acid, 12-hydroxy-, (9Z,12R)-, polymer with 1,2,3-propanetriol, 9-Octadecenoic acid, 12-hydroxy-,(9Z,12R)- monoester with triglycerol, Akoline PGPR, PGPR, Polyglycerol polyricinoleate, Polyglycerol polyricinoleate (PGPR), Polyglycerol polyricinoleic acid, Polyglyceryl-3 ricinoleate, Polyglyceryl-3 ricinoleate [INCI], Triglyceryl monoricinoleate, UNII-MZQ63P0N0W.

Polyglycerol polyricinoleate (PGPR), E476, is an emulsifier made from glycerol and fatty acids (usually from castor bean, but also from soybean oil).
In chocolate, compound chocolate and similar coatings, Polyglycerol polyricinoleate (PGPR) is mainly used with another substance like lecithin to reduce viscosity.
Polyglycerol polyricinoleate (PGPR) is used at low levels (below 0.5%), and works by decreasing the friction between the solid particles (e.g. cacao, sugar, milk) in molten chocolate, reducing the yield stress so that it flows more easily, approaching the behaviour of a Newtonian fluid.

Polyglycerol polyricinoleate (PGPR) is a food additive commonly used as an emulsifier in the food industry.
Polyglycerol polyricinoleate (PGPR) is derived from natural sources, primarily castor beans, and is composed of polyglycerol and fatty acids, primarily ricinoleic acid.
Polyglycerol polyricinoleate (PGPR) is heated to above 200 °C in a reactor in the presence of an alkaline catalyst to create polyglycerol.

Castor oil fatty acids are separately heated to above 200 °C, to create interesterified ricinoleic fatty acids.
The polyglycerol and the interesterified ricinoleic fatty acids are then mixed to create Polyglycerol polyricinoleate (PGPR).
Polyglycerol polyricinoleate (PGPR) improves the flow characteristics of chocolate and compound chocolate, especially near the melting point, it can improve the efficiency of chocolate coating processes: chocolate coatings with PGPR flow better around shapes of enrobed and dipped products, and it also improves the performance of equipment used to produce solid molded products: the chocolate flows better into the mold, and surrounds inclusions and releases trapped air more easily.

Polyglycerol polyricinoleate (PGPR) can also be used to reduce the quantity of cocoa butter needed in chocolate formulations: the solid particles in chocolate are suspended in the cocoa butter, and by reducing the viscosity of the chocolate, less cocoa butter is required, which saves costs, because cocoa butter is an expensive ingredient, and also leads to a lower-fat product.
Polyglycerol polyricinoleate (PGPR) was re‐evaluated in 2017 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS).
Polyglycerol polyricinoleate (PGPR), is an emulsifier made from glycerol and fatty acids -usually from castor bean, but also from soybean oil-.

In chocolate, compound chocolate and similar coatings, Polyglycerol polyricinoleate (PGPR) is mainly used with another substance like lecithin to reduce viscosity.
Polyglycerol polyricinoleate (PGPR) is used at low levels -below 0.5%-, and works by decreasing the friction between the solid particles -e.g. cacao, sugar, milk- in molten chocolate, reducing the yield stress so that it flows more easily, approaching the behaviour of a Newtonian fluid.
It can also be used as an emulsifier in spreads and in salad dressings, or to improve the texture of baked goods.

Polyglycerol polyricinoleate (PGPR) is made up of a short chain of glycerol molecules connected by ether bonds, with ricinoleic acid side chains connected by ester bonds.
Polyglycerol polyricinoleate (PGPR) is a yellowish, viscous liquid, and is strongly lipophilic: it is soluble in fats and oils and insoluble in water and ethanol.
Polyglycerol polyricinoleate (PGPR), is an emulsifier derived from castor bean oil and often used to improve processing characteristics of chocolate.

Polyglycerol polyricinoleate (PGPR) was first used in chocolate in England in 1952; since then, it has been used in various food applications such as cooking oils and fats, stick margarine, spreads, low fat dressings, ice cream and flour.
Polyglycerol polyricinoleate (PGPR), is an ingredient commonly used as a water-in-oil type (W/O) emulsifier in chocolate and chocolate-type confectionary to reduce the viscosity in production.
Polyglycerol polyricinoleate (PGPR) is a type of polyglycerol esters (PGE) with the European food additive number E476.

Polyglycerol polyricinoleate (PGPR) is a mixture of esterified products manufactured by the esterification of polyglycerol with condensed castor oil fatty acids.
The brief 3 step manufacturing processes as follows:
Polyglycerol polyricinoleate (PGPR) is heated to above 200 ℃ in the presence of an alkali catalyst to produce polyglycerol.

Polyglycerol polyricinoleate (PGPR) is an emulsifier manufactured from Interesterified Castor oil fatty acids and Polymerized Glycerol.
It is a highly lipophilic emulsifier with a low Hydrophilic-Lipophilic Balance.
This food additive is a viscous amber coloured liquid.

Polyglycerol polyricinoleate (PGPR) is insoluble in hot and cold water, soluble in oils and fats.
Polyglycerol polyricinoleate (PGPR) works by reducing the friction between the particles of the solid ingredients in molten chocolate and reducing the surface tension or yield stress (Casson yield value) so that chocolate flows much more uniformly and in an easily controllable manner.
This greatly aids the application of chocolate in bar-making, moulding, enrobing and coating.

Polyglycerol polyricinoleate (PGPR) is also a cost-saving emulsifier as it reduces the quantity of fat required in chocolate production to achieve the desired chocolate viscosity.
Polyglycerol polyricinoleate (PGPR) is an emulsifier manufactured from Interesterified Castor oil fatty acids and Polymerized Glycerol.
It is a highly lipophilic emulsifier with a low Hydrophilic-Lipophilic Balance.

Polyglycerol polyricinoleate (PGPR) is a viscous amber coloured liquid and is insoluble in hot and cold water, soluble in oils and fats.
Polyglycerol Polyricinoleate (PGPR) is an emulsifier made from glycerol and fatty acids.
In chocolate, Polyglycerol polyricinoleate (PGPR) is used with lecithin to reduce viscosity.

Polyglycerol polyricinoleate (PGPR) can also be used as an emulsifier in salad dressings and spreads or to improve the texture of baked goods.
Polyglycerol polyricinoleate (PGPR) is a yellow, viscous liquid.
Polyglycerol polyricinoleate (PGPR) is one of those mysterious chemicals that manufacturers use in food production.

It stabilizes low-fat, high-water margarines and helps the "flow properties" in candy production.
Polyglycerol polyricinoleate (PGPR) is a combination of polyglycerol and castor oil (oil of the Ricinus communis tree).
Normal fat consists of glycerol and fatty acids, for these products additional glycerol is coupled to the normal glycerol.

The product generally is a mixture of different components but has a certain element as synthetic as it uses an acetone-benzene solution.
Polyglycerol polyricinoleate (PGPR) is becoming increasingly popular in Chocolate bars from the lower end market and are sold in bulk to offload costs.
Polyglycerol polyricinoleate (PGPR) is also used in polymer coatings, paint and as a coating for plastic film to aid in anti-fogging.

Polyglycerol polyricinoleate (PGPR) is a viscous, yellow liquid that has good thermal stability.
Polyglycerol polyricinoleate (PGPR) is soluble in hot grease and insoluble in cold water and ethanol.
Polyglycerol polyricinoleate (PGPR) can be used in chocolate products, candy, ice cream coating, etc.

Polyglycerol polyricinoleate (PGPR) is derived from glycerol and fatty acids, primarily ricinoleic acid obtained from castor oil.
Polyglycerol polyricinoleate (PGPR) consists of polyglycerol chains esterified with ricinoleic acid molecules.
The number of glycerol units in the polyglycerol chain can vary, resulting in different molecular weights and properties.

Polyglycerol polyricinoleate (PGPR) is typically produced by the esterification of glycerol with ricinoleic acid, followed by purification processes to isolate the desired PGPR molecules.
Polyglycerol polyricinoleate (PGPR) can also be synthesized from other sources of fatty acids and glycerol, but castor oil is commonly used due to its high ricinoleic acid content.
Polyglycerol polyricinoleate (PGPR) functions as an emulsifier, helping to stabilize oil-in-water emulsions by reducing the interfacial tension between oil and water phases.

It forms a protective layer around oil droplets, preventing them from coalescing and improving the dispersion of oil in water.
This property is particularly useful in chocolate and confectionery products to ensure proper texture, smoothness, and mouthfeel.
Polyglycerol polyricinoleate (PGPR) is widely used in the chocolate industry to reduce the viscosity of chocolate and facilitate the flow of chocolate during molding, enrobing, and coating processes.

By improving the fluidity of chocolate, Polyglycerol polyricinoleate (PGPR) allows for faster and more efficient production while maintaining the desired texture and appearance of the final product.
In addition to its emulsifying properties, Polyglycerol polyricinoleate (PGPR) can also function as a fat replacer in certain food products, allowing for the reduction of total fat content without compromising texture or sensory attributes.
This can be beneficial for producing low-fat or reduced-fat food formulations while maintaining desirable mouthfeel and taste.

Polyglycerol polyricinoleate (PGPR) is approved for use as a food additive in many countries, including the United States and the European Union.
Polyglycerol polyricinoleate (PGPR) is generally recognized as safe (GRAS) when used within the recommended limits.
Regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA) have evaluated its safety for human consumption.

Polyglycerol polyricinoleate (PGPR) may be listed on ingredient labels of food products as “polyglycerol polyricinoleate” or by its abbreviation “PGPR.”
Polyglycerol polyricinoleate (PGPR) is typically identified by its E number, E476, in the European Union.
Polyglycerol polyricinoleate (PGPR), is an emulsifier made from glycerol and fatty acids (usually from castor bean, but also from soybean oil).

In chocolate, compound chocolate and similar coatings, Polyglycerol polyricinoleate (PGPR) is mainly used with another substance like lecithin to reduce viscosity.
Polyglycerol polyricinoleate (PGPR)e is used at low levels (below 0.5%), and works by decreasing the friction between the solid particles (e.g. cacao, sugar, milk) in molten chocolate, reducing the yield stress so that it flows more easily.
Polyglycerol polyricinoleate (PGPR) can also be used as an emulsifier in spreads and in salad dressings, or to improve the texture of baked goods.

Polyglycerol polyricinoleate (PGPR) is an emulsifier made in a three-step process from glycerol and fatty acids.
Polyglycerol polyricinoleate (PGPR) is made up of a short chain of glycerol molecules connected by ether bonds, with ricinoleic acid side chains connected by ester bonds.
Polyglycerol polyricinoleate (PGPR) is also used in food as a release agent.

Polyglycerol polyricinoleate (PGPR) is a W/O type surfactant, which can be used as an emulsifier, stabilizer, thickener, and anticaking agent.
Polyglycerol polyricinoleate (PGPR) is widely used in the fields of food and cosmetics.
Polyglycerol polyricinoleate (PGPR) is a special emulsifier that can stabilize water-in-oil systems with high water content.

Polyglycerol polyricinoleate (PGPR) adjusts the surface tension.
Polyglycerol polyricinoleate (PGPR) adjusts product viscosity.
Its lipophilic group is Polyglycerol polyricinoleate (PGPR) acid, and its hydrophilic group is polyglycerin group.

Polyglycerol polyricinoleate (PGPR) has good solubility in grease.
Polyglycerol polyricinoleate (PGPR) is widely used in food (chocolate and its products, ice cream icing, etc.), cosmetics, lubricants and other fields.
Polyglycerol polyricinoleate (PGPR) to produce better quality chocolate reducing cocoa oil quantity in chocolate industry.

Polyglycerol polyricinoleate (PGPR) provides easier discharge property eliminating bubble formation and empty holes.
Polyglycerol polyricinoleate (PGPR) serves to produce chocolate with desired refirement.
Polyglycerol polyricinoleate (PGPR) is an emulsifier commonly used in the food industry.

As veganism continues to gain popularity, many individuals following a plant-based lifestyle are questioning whether or not PGPR can be considered vegan-friendly.
In this article, we will explore the chemical composition of PGPR, its common uses in the food industry, and evaluate its vegan status.
Additionally, will identify alternatives to Polyglycerol polyricinoleate (PGPR) for those wishing to avoid it in their vegan diets, and discuss the impact of ingredient transparency on vegan choices.

Polyglycerol polyricinoleate (PGPR) has found widespread use in the food industry due to its remarkable emulsifying properties.
One of its most common applications is in the production of chocolate products.
When bite into a smooth and creamy chocolate bar, can thank Polyglycerol polyricinoleate (PGPR) for its role in achieving that delightful texture.

In chocolate manufacturing, Polyglycerol polyricinoleate (PGPR) aids in the smooth blending of cocoa butter with other ingredients, ensuring a consistent and velvety mouthfeel.
But Polyglycerol polyricinoleate (PGPR)'s influence extends far beyond the realm of chocolate.
Polyglycerol polyricinoleate (PGPR) is also widely used in baked goods, such as cakes, cookies, and pastries.

By incorporating Polyglycerol polyricinoleate (PGPR) into the dough or batter, bakers can achieve improved texture and moisture retention, resulting in delectable treats that stay fresh for longer periods of time.
Polyglycerol polyricinoleate (PGPR) acts as an emulsifier, helping to stabilize oil-in-water emulsions by reducing the surface tension between oil and water molecules.
This property makes it particularly useful in chocolate and confectionery manufacturing, where it helps prevent the separation of cocoa butter and cocoa solids, improve viscosity, and enhance the flow properties of chocolate.

In chocolate products, Polyglycerol polyricinoleate (PGPR) contributes to a smoother texture and mouthfeel by preventing the formation of fat bloom, a crystallization phenomenon that occurs when chocolate is improperly tempered or stored at incorrect temperatures.
By dispersing cocoa butter more evenly throughout the chocolate matrix, Polyglycerol polyricinoleate (PGPR) helps maintain a desirable texture and appearance.
Polyglycerol polyricinoleate (PGPR) can also be used to reduce the amount of cocoa butter or other fats needed in chocolate formulations while maintaining product quality.

This can result in cost savings for manufacturers and potentially lower calorie content in finished products, making it a valuable ingredient in reduced-fat or lower-calorie chocolate products.
Polyglycerol polyricinoleate (PGPR) is approved for use as a food additive by regulatory authorities such as the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).
Polyglycerol polyricinoleate (PGPR) is listed as Generally Recognized as Safe (GRAS) in the United States and is permitted for use in various food categories, including chocolate and chocolate confectionery.

In ingredient lists, Polyglycerol polyricinoleate (PGPR) may be listed by its full name, "Polyglycerol polyricinoleate," or by its abbreviation, "PGPR."
Polyglycerol polyricinoleate (PGPR) is identified by the INS number 476 in the International Numbering System for Food Additives.

Polyglycerol polyricinoleate (PGPR) is generally considered non-allergenic, although individuals with sensitivities to certain food additives or ingredients should exercise caution.
Polyglycerol polyricinoleate (PGPR) is also suitable for vegetarian and vegan diets, as it is derived from plant sources.

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Polyglycerol polyricinoleate (PGPR), is an emulsifier made from glycerol and fatty acids (usually from castor bean, but also from soybean oil).
In chocolate, compound chocolate and similar coatings, Polyglycerol polyricinoleate (PGPR) is mainly used with another substance like lecithin to reduce viscosity.
Polyglycerol polyricinoleate (PGPR) is used at low levels (below 0.5 %), and works by decreasing the friction between the solid particles (e.g. cacao, sugar, milk) in molten chocolate, reducing the yield stress so that it flows more easily, approaching the behaviour of a Newtonian fluid.

It can also be used as an emulsifier in spreads and in salad dressings, or to improve the texture of baked goods.
Polyglycerol polyricinoleate (PGPR) is made up of a short chain of glycerol molecules connected by ether bonds, with ricinoleic acid side chains connected by ester bonds.
Polyglycerol polyricinoleate (PGPR) is a yellowish, viscous liquid, and is strongly lipophilic: it is soluble in fats and oils and insoluble in water and ethanol.

Because Polyglycerol polyricinoleate (PGPR) improves the flow characteristics of chocolate and compound chocolate, especially near the melting point, it can improve the efficiency of chocolate coating processes: chocolate coatings with Polyglycerol polyricinoleate (PGPR) flow better around shapes of enrobed and dipped products, and it also improves the performance of equipment used to produce solid molded products: the chocolate flows better into the mold, and surrounds inclusions and releases trapped air more easily.
Polyglycerol polyricinoleate (PGPR) can also be used to reduce the quantity of cocoa butter needed in chocolate formulations: the solid particles in chocolate are suspended in the cocoa butter, and by reducing the viscosity of the chocolate, less cocoa butter is required, which saves costs, because cocoa butter is an expensive ingredient, and also leads to a lower-fat product.

Polyglycerol polyricinoleate (PGPR) serves to produce better quality chocolate reducing cocoa oil quantity in chocolate industry.
Polyglycerol polyricinoleate (PGPR) provides easier discharge property eliminating bubble formation and empty holes.
Polyglycerol polyricinoleate (PGPR) serves to produce chocolate with desired refirement.

Polyglycerol polyricinoleate (PGPR) doesnt have any bad odour.
It has a good thermal stability.
It is suitable to use together with lecithin.

Polyglycerol polyricinoleate (PGPR) makes the process easier.
Polyglycerol Polyricinoleate (PGPR), E476, is an emulsifier made from castor beans which reduces the viscosity of chocolate and similar coatings and compounds.
It works by decreasing the friction between the particles of cacao, sugar, milk, etc. present so that they can flow more easily when melted.

Polyglycerol polyricinoleate (PGPR) is used at low levels (fractions of percents.)
Polyglycerol polyricinoleate (PGPR)'s primary function lies in emulsification, allowing for efficient dispersion of fats in water-based solutions, particularly in chocolate.
This property prevents ingredient separation, ensuring homogeneous texture and consistency.

Polyglycerol polyricinoleate (PGPR)s remarkable ability to decrease viscosity facilitates smoother chocolate handling during manufacturing, contributing to streamlined production processes.
Polyglycerol polyricinoleate (PGPR) enhances the stability of emulsions, thereby extending the shelf life of products.
By averting ingredient separation and maintaining texture integrity, it ensures product quality and consumer satisfaction over time.

Polyglycerol polyricinoleate (PGPR) is integral to chocolate manufacturing, enhancing its flow properties during molding and coating stages.
By reducing chocolate viscosity, it facilitates smoother handling and coating of various confectionery items.
Polyglycerol polyricinoleate (PGPR) emulsifier plays a pivotal role in various confectionery products like candy bars, coatings, and fillings.

Its inclusion improves texture and stability, ensuring a consistent quality in the end products.
In certain instances, Polyglycerol polyricinoleate (PGPR) emulsifier is utilized in bakery goods to bolster texture and prolong shelf life.
Polyglycerol polyricinoleate (PGPR) is typically produced through the esterification of polyglycerol with fatty acids derived from castor oil, which is rich in ricinoleic acid.

The process involves heating and reacting the ingredients under controlled conditions to form the desired polyglycerol fatty acid esters.
Polyglycerol polyricinoleate (PGPR) is a complex mixture of polyglycerol esters of ricinoleic acid, with varying degrees of polymerization and esterification.
The polyglycerol portion consists of multiple glycerol units linked together, while the ricinoleic acid portion provides the hydrophobic properties necessary for emulsification.

In chocolate manufacturing, Polyglycerol polyricinoleate (PGPR) acts as a crystallization inhibitor, interfering with the formation of large cocoa butter crystals and promoting the formation of smaller, more stable crystals.
This results in smoother chocolate with improved snap, shine, and resistance to fat bloom.
Polyglycerol polyricinoleate (PGPR) is compatible with cocoa butter, the primary fat in chocolate, and does not affect its flavor or aroma.

Polyglycerol polyricinoleate (PGPR) helps disperse cocoa butter evenly throughout the chocolate mass, facilitating tempering and molding processes.
Polyglycerol polyricinoleate (PGPR) is also used in compound chocolate coatings, which are chocolate-like coatings used in products such as ice cream bars, biscuits, and snacks.
Polyglycerol polyricinoleate (PGPR) improves the flow properties of the coating, enhances adhesion to the substrate, and provides a glossy finish.

Chocolate products containing Polyglycerol polyricinoleate (PGPR) exhibit improved stability during storage, with reduced susceptibility to fat bloom and other quality defects.
Proper storage conditions, including temperature and humidity control, help maintain the quality of chocolate products over time.
Polyglycerol polyricinoleate (PGPR) is approved for use as a food additive in many countries worldwide, including the United States, European Union, Japan, and Australia.

Polyglycerol polyricinoleate (PGPR) is included in the Codex Alimentarius, an international food standards code, and is subject to regulatory oversight to ensure safety and compliance with food regulations.
Ongoing research efforts focus on optimizing the properties and performance of PGPR in chocolate and confectionery applications.
This includes exploring new production methods, evaluating alternative sources of raw materials, and studying its potential synergies with other emulsifiers and additives.

Polyglycerol polyricinoleate (PGPR) is generally regarded as safe and does not impart any noticeable taste or odor to chocolate products, some consumers may prefer products made without additional emulsifiers.
Manufacturers may address consumer preferences by offering alternative formulations or labeling products accordingly.
Polyglycerol polyricinoleate (PGPR)s most important feature is that it can reduce the viscosity of the chocolate slurry without forming crystals, thereby improving its fluidity.

Polyglycerol polyricinoleate (PGPR) has a good synergistic effect when mixed with lecithin, which can significantly reduce the shear stress of chocolate, reduce the amount of cocoa butter and cocoa butter substitutes, and reduce the thickness of the chocolate coating and the ease of processing.
Polyglycerol polyricinoleate (PGPR) makes chocolate and its products easy to discharge the small bubbles generated in the process of filling the mold, and avoid the phenomenon of voids and pores in the product.
Polyglycerol polyricinoleate (PGPR) reduces the amount of chocolate required for effective slurrying and molding; speeds up the injection molding of chocolate.

Polyglycerol polyricinoleate (PGPR) improves the ease of processing of the product, makes the chocolate icing of the biscuit evenly thick, and the icing thinner and flatter, so that the wrapped air can be released more easily.
In a humid environment, Polyglycerol polyricinoleate (PGPR) increases the low-temperature adhesion of the chocolate coating, so that the chocolate icing of the ice cream can be formed quickly, accelerate its adhesion, increase the adhesion, and reduce the tiny pores.
Polyglycerol polyricinoleate (PGPR) and 0.3% lecithin to chocolate, the shear stress can be reduced by about 50%, or use 0.2% polyglycerol polyricinoleate and 0.5% lecithin together, can reduce the amount of cocoa butter by about 8%, reduces the thickness of the chocolate coating, and improves the ease of processing.

Polyglycerol polyricinoleate (PGPR) is a complex mixture derived from castor beans, a plant native to Africa and commonly grown in Brazil, China, and India.
This emulsifier plays a crucial role in the food industry, contributing to the texture and stability of various food products.
Let's delve deeper into the fascinating world of Polyglycerol polyricinoleate (PGPR) and explore its chemical composition, as well as its common uses in the food industry.

The chemical structure of Polyglycerol polyricinoleate (PGPR) is truly remarkable.
Polyglycerol polyricinoleate (PGPR) consists of multiple glycerol and ricinoleic acid units bonded together, forming a complex composition that gives it its emulsifying properties.
Glycerol, a colorless and odorless liquid, is a key component in the structure of Polyglycerol polyricinoleate (PGPR).

Ricinoleic acid, on the other hand, is a fatty acid extracted from castor oil, which is obtained from the seeds of the castor bean plant.
The unique combination of glycerol and ricinoleic acid in Polyglycerol polyricinoleate (PGPR) allows it to effectively stabilize mixtures of oil and water, making it an invaluable ingredient in the food industry.
Polyglycerol polyricinoleate (PGPR) is characterized by its intermediate hydrophilic-lipophilic balance (HLB), which allows it to effectively stabilize oil-in-water emulsions without causing excessive oiliness or greasiness in food products.

This property makes it suitable for use in a wide range of applications beyond chocolate, including baked goods, spreads, and dairy alternatives.
In addition to its role as a crystallization inhibitor, Polyglycerol polyricinoleate (PGPR) helps reduce the viscosity of chocolate formulations, making them easier to handle during processing.
This is particularly beneficial in large-scale chocolate manufacturing operations, where efficient flow and molding properties are essential for productivity and product consistency.

Polyglycerol polyricinoleate (PGPR) is widely accepted as a safe and effective emulsifier, some consumers and food manufacturers may prefer "clean label" alternatives with simpler ingredient profiles.
In response to this demand, manufacturers may explore natural or plant-based emulsifiers as substitutes for Polyglycerol polyricinoleate (PGPR), although achieving comparable performance characteristics can be challenging.
Polyglycerol polyricinoleate (PGPR) must meet specific regulatory specifications regarding purity, composition, and manufacturing practices to ensure its safety and suitability for use in food products.

Regulatory agencies such as the FDA in the United States and the EFSA in the European Union establish these specifications and oversee compliance through rigorous testing and monitoring.
Polyglycerol polyricinoleate (PGPR) is primarily used in the food industry, it also finds applications in other sectors, including pharmaceuticals, personal care products, and industrial applications.
In pharmaceutical formulations, Polyglycerol polyricinoleate (PGPR) may serve as a solubilizer or emulsifier in liquid medications, creams, and ointments.

In personal care products, it can be used as an emulsifier or viscosity modifier in lotions, creams, and hair care products.
As consumer awareness of environmental issues grows, there is increasing interest in sustainable sourcing and production practices for food additives like Polyglycerol polyricinoleate (PGPR).
Manufacturers may prioritize sourcing raw materials from certified sustainable and ethically responsible suppliers, as well as implementing environmentally friendly production processes to minimize waste and energy consumption.

The global trade of PGPR and chocolate products containing PGPR is subject to international trade agreements and regulations.
Harmonization of standards and mutual recognition agreements facilitate the smooth flow of goods across borders, ensuring consistent quality and safety for consumers worldwide.
Collaborative research initiatives involving academia, industry, and government agencies aim to advance the understanding of Polyglycerol polyricinoleate (PGPR)'s properties, applications, and safety profile.

These initiatives may focus on areas such as toxicology, product development, and sustainability to address emerging challenges and opportunities in the use of Polyglycerol polyricinoleate (PGPR).
Food manufacturers and regulatory agencies play a role in educating consumers about the safety and functionality of Polyglycerol polyricinoleate (PGPR) in food products.
Transparent labeling practices, clear communication of ingredient information, and engagement with consumer feedback contribute to building trust and confidence in the use of PGPR as a food additive.

Ongoing innovation in emulsifier technology seeks to enhance the performance, versatility, and sustainability of Polyglycerol polyricinoleate (PGPR) and other food additives.
This includes the development of novel formulations, process improvements, and alternative sources of raw materials to meet evolving consumer preferences and industry needs.

Uses:
Polyglycerol polyricinoleate (PGPR) facilitates the mixing of water and oil and is therefore used as an emulsifier in cosmetics.
Polyglycerol polyricinoleate (PGPR) is particularly useful in butter lip balms and other soft to low viscosity water-in-oil emulsions that have a pleasant, non-greasy skin feel.
Polyglycerol polyricinoleate (PGPR) is also use as a stabiliser, thickener and anti-caking agent.

Polyglycerol polyricinoleate (PGPR) helps to adjust the surface tension and viscosity of products.
It is used at concentrations of 0.1-3.0 per cent.
An emulsifier is an ingredient that is typically used in food production as a way to keep fat and water from separating in the product.

When cooking at home, egg yolks are often used as an emulsifier.
Emulsifiers also are used in the confectionery industry to improve the flow characteristics of chocolate so that it can be pumped more freely in a manufacturing plant.
They also facilitate the molding of chocolates into various shapes.

Another emulsifier commonly used in chocolate is soy lecithin, which is usually obtained from soybeans.
Polyglycerol polyricinoleate (PGPR) is a commonly-used and a safe ingredient.
The U.S. Food and Drug Administration (U.S. FDA) and other international regulatory authorities have reviewed PGPR and indicate that it is safe and suitable for use in food production.

Polyglycerol polyricinoleate (PGPR) as an emulsifier, stabiliser allowing chocolate coating to be spread more thinly to save costs.
This is done at the expense of cocoa butter, which is eliminated from certain chocolate, namely Hershey’s, and PGPR used instead.
Polyglycerol polyricinoleate (PGPR) is also used in spreadable fats and spreads, creamers and dressings of various kinds, where a plastic viscosity is desired in the products.

Used in chocolate, Polyglycerol polyricinoleate (PGPR) can significantly improve the mobility of chocolate products, and save the amount of cocoa butter.
Speed up the process of filling and mold forming for chocolate products, optimize the process and make the small bubbles discharge easily, avoid empty holes occurring and pores in the chocolate products.
Used with lecithin, PGPR has a good synergistic effect, thinning the thickness of the chocolate coating to make it easy to process.

Polyglycerol polyricinoleate (PGPR), identified with the code E-476, is a food additive used primarily as an emulsifier in various industries.
Polyglycerol polyricinoleate (PGPR) is made from glycerol and fatty acids, typically derived from castor bean or soybean oil.
At HanielSoyatech, we specialize in producing high-quality, non-GMO Polyglycerol polyricinoleate (PGPR) from non-GMO soybeans, ensuring the finest ingredients for our customers.

Polyglycerol polyricinoleate (PGPR) is extensively used in chocolate manufacturing to improve the texture, flow properties, and stability of chocolate products.
It helps prevent fat bloom, a phenomenon where cocoa butter separates from the chocolate matrix, by promoting the formation of smaller and more stable cocoa butter crystals.
Polyglycerol polyricinoleate (PGPR) also facilitates the molding and enrobing processes in chocolate production.

In bakery applications, Polyglycerol polyricinoleate (PGPR) may be added to dough formulations to improve dough handling properties, increase volume, and enhance texture.
It can also be used as an emulsifier in cake batters, bread doughs, and pastry fillings to improve crumb structure and extend shelf life.
Polyglycerol polyricinoleate (PGPR) is used in the production of compound chocolate coatings for applications such as coating biscuits, cookies, and snack bars.

Polyglycerol polyricinoleate (PGPR) helps create a smooth and glossy coating while providing good adhesion to the substrate.
Polyglycerol polyricinoleate (PGPR) is sometimes incorporated into ice cream formulations to improve overrun, texture, and resistance to melting.
Polyglycerol polyricinoleate (PGPR) helps stabilize emulsions and prevents the formation of ice crystals, resulting in a smoother and creamier product.

Polyglycerol polyricinoleate (PGPR) can be used in dairy alternative products such as plant-based ice creams, yogurts, and cheeses to improve texture and mouthfeel.
It helps stabilize oil-in-water emulsions and prevents fat separation during processing and storage.
Polyglycerol polyricinoleate (PGPR) may be added to various processed foods, including sauces, dressings, and spreads, to enhance emulsion stability, viscosity, and mouthfeel.

It helps prevent oil and water from separating and improves the overall sensory properties of the product.
In the personal care industry, Polyglycerol polyricinoleate (PGPR) is used as an emulsifier and stabilizer in cosmetic formulations such as lotions, creams, and hair care products.
Polyglycerol polyricinoleate (PGPR) helps create uniform emulsions, improves product spreadability, and enhances skin feel.

Polyglycerol polyricinoleate (PGPR) can be found in pharmaceutical formulations as an emulsifier in creams, ointments, and topical solutions.
It aids in the dispersion of active ingredients and enhances the delivery of therapeutic agents to the skin.
Polyglycerol polyricinoleate (PGPR) may have applications in industrial processes, such as lubricants, where its emulsifying properties are utilized to stabilize oil-water mixtures and improve fluid properties.

Polyglycerol polyricinoleate (PGPR) can be used in dairy products such as creamers, whipped toppings, and custards to improve texture, stability, and mouthfeel.
It helps prevent syneresis (separation of liquid from gel) and enhances the creaminess of dairy-based products.
Polyglycerol polyricinoleate (PGPR) may be incorporated into nutritional supplements, including protein powders, meal replacement shakes, and vitamin-fortified drinks, to improve the dispersion of fat-soluble vitamins and enhance the overall palatability of the product.

In meat and poultry processing, Polyglycerol polyricinoleate (PGPR) can be used as an emulsifier in marinades, brines, and injected solutions to improve moisture retention, flavor distribution, and tenderness in processed meat products such as sausages, deli meats, and marinated cuts.
Polyglycerol polyricinoleate (PGPR) may be added to fish and seafood products, including surimi-based products, fish cakes, and seafood analogs, to improve binding properties, texture, and stability during processing and cooking.
Polyglycerol polyricinoleate (PGPR) is used in the production of snack foods such as potato chips, pretzels, and crackers to improve the dispersion of flavorings and seasonings, enhance crispiness, and reduce oil absorption during frying or baking.

Beyond the food industry, Polyglycerol polyricinoleate (PGPR) finds applications in non-food sectors such as pharmaceuticals, personal care, and industrial products.
In pharmaceuticals, it may be used as an excipient or solubilizer in tablet coatings, topical formulations, and oral suspensions.
In personal care products, it serves as an emulsifier, stabilizer, and viscosity modifier in creams, lotions, and hair care products.

In industrial applications, Polyglycerol polyricinoleate (PGPR) can be used as a lubricant additive, emulsion stabilizer, or dispersant in various formulations.
With growing consumer demand for clean label and natural ingredients, there is increasing interest in developing Polyglycerol polyricinoleate (PGPR) alternatives derived from renewable sources or using simpler processing methods.
These alternatives aim to provide similar functionality while meeting clean label criteria and consumer preferences.

Polyglycerol polyricinoleate (PGPR) usage is regulated by food safety authorities worldwide, including the FDA in the United States, EFSA in the European Union, and JECFA at the international level.
Regulatory approvals ensure that PGPR meets safety standards and permissible usage levels in food and non-food applications.
Polyglycerol polyricinoleate (PGPR) may be included in dietary supplements, such as omega-3 fatty acid supplements, to improve the dispersion and absorption of fat-soluble nutrients.

Polyglycerol polyricinoleate (PGPR) helps ensure uniform distribution of active ingredients in supplement formulations, enhancing their bioavailability and effectiveness.
Polyglycerol polyricinoleate (PGPR) can be incorporated into pet food formulations, including dry kibble, wet food, and treats, to improve palatability, texture, and shelf stability.
Polyglycerol polyricinoleate (PGPR) helps maintain the integrity of pet food products during processing, packaging, and storage.

In the cosmetics and personal care industry, Polyglycerol polyricinoleate (PGPR) is used as an emulsifier, stabilizer, and thickening agent in various formulations, including creams, lotions, serums, and makeup products.
Polyglycerol polyricinoleate (PGPR) contributes to the smooth texture, uniform appearance, and enhanced performance of cosmetic formulations.
Polyglycerol polyricinoleate (PGPR) may be added to hair care products such as shampoos, conditioners, and styling gels to improve emulsion stability, enhance product spreadability, and provide conditioning benefits.

It helps distribute active ingredients evenly throughout the hair and scalp, promoting hydration and manageability.
Polyglycerol polyricinoleate (PGPR) can be utilized as an emulsifier or surfactant in industrial lubricants, hydraulic fluids, and metalworking fluids to improve lubricity, reduce friction, and enhance performance.
It helps disperse additives and contaminants in lubricant formulations, ensuring optimal lubrication and equipment protection.

In the paints and coatings industry, Polyglycerol polyricinoleate (PGPR) may be used as a dispersant or wetting agent to improve pigment dispersion, reduce viscosity, and enhance coating properties such as flow, leveling, and adhesion.
It helps achieve uniform coverage and color consistency in paint formulations.
Polyglycerol polyricinoleate (PGPR) can be incorporated into adhesive and sealant formulations to improve emulsion stability, tackiness, and bonding strength.

It helps ensure uniform distribution of adhesive components and enhances the adhesion of bonded surfaces in various applications, including packaging, construction, and automotive assembly.
Polyglycerol polyricinoleate (PGPR) may serve as a processing aid or compatibilizer in polymer formulations, such as thermoplastics, elastomers, and composite materials.
It helps improve the dispersion of additives, fillers, and reinforcing agents, leading to enhanced mechanical properties and processing efficiency.

Polyglycerol polyricinoleate (PGPR) can be used as a foam stabilizer or antifoaming agent in food and non-food applications to control foam formation and stability.
It helps prevent excessive foaming during food processing, brewing, and fermentation processes, as well as in industrial applications such as wastewater treatment and detergent manufacturing.

Safety Profile:
The FDA has deemed Polyglycerol polyricinoleate (PGPR) to be generally recognized as safe for human consumption, and the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has also deemed it safe.
Both of these organisations set the acceptable daily intake at 7.5 milligrams per kilogram of body weight.
In 2017, a panel from the European Food Safety Authority recommended an increased acceptable daily intake of 25 milligrams per kilogram of body weight based on a new chronic toxicity and carcinogenicity study.

In Europe, Polyglycerol polyricinoleate (PGPR) is allowed in chocolate up to a level of 0.5%.
In a 1998 review funded by Unilever of safety evaluations from the late 1950s and early 1960s, "Polyglycerol polyricinoleate (PGPR) was found to be 98% digested by rats and utilized as a source of energy superior to starch and nearly equivalent to peanut oil."
Additionally, no evidence was found of interference with normal fat metabolism, nor with growth, reproduction, and maintenance of tissue.

Overall, it did not "constitute a human health hazard".
A study published in the European Food Safety Authority in 2017 re-evaluated the safety of the additive and recommended to revise the acceptable daily intake and increase it to 25 milligrams per kilogram of body weight.
Direct contact with concentrated Polyglycerol polyricinoleate (PGPR) formulations may cause irritation to the skin and eyes in sensitive individuals.

It is important to use appropriate personal protective equipment (PPE), such as gloves and safety goggles, when handling PGPR in its concentrated form to minimize the risk of irritation.
Inhalation of Polyglycerol polyricinoleate (PGPR) dust or aerosols may irritate the respiratory tract and mucous membranes, leading to coughing, wheezing, or respiratory discomfort.
Adequate ventilation should be maintained in areas where PGPR is handled or processed to minimize the potential for airborne exposure.

While rare, some individuals may experience allergic reactions to Polyglycerol polyricinoleate (PGPR) or its components. Symptoms of an allergic reaction may include skin rash, itching, swelling, or respiratory symptoms such as difficulty breathing.
Individuals with known sensitivities or allergies to related compounds should exercise caution when exposed to PGPR-containing products.

POLYGLYCERYL-10 CAPRYLATE
POLYGLYCERYL-10 DIOLEATE, N° CAS : 33940-99-7. Nom INCI : POLYGLYCERYL-10 DIOLEATE. N° EINECS/ELINCS : 251-750-2. Ses fonctions (INCI) : Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)
POLYGLYCERYL-10 DIOLEATE
POLYGLYCERYL-10 LAURATE, N° CAS : 34406-66-1, Origine(s) : Végétale, Synthétique, Nom INCI : POLYGLYCERYL-10 LAURATE. Compatible Bio (Référentiel COSMOS). Le Polyglyceyrl-10 Laurate aussi appelé acide dodécanoïque est un ester d'acide laurique et de polyglycérine-10. C'est un émulsifiant qui permet la réalisation des émulsions, à partir d'huile et d'eau.Ses fonctions (INCI). Agent d'entretien de la peau : Maintient la peau en bon état
POLYGLYCERYL-10 LAURATE
POLYGLYCERYL-10 OLEATE, N° CAS : 79665-93-3, Nom INCI : POLYGLYCERYL-10 OLEATE, N° EINECS/ELINCS : 279-230-0. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI): Agent d'entretien de la peau : Maintient la peau en bon état
POLYGLYCERYL-10 LAURATE
POLYGLYCERYL-10 LAURATE is classified as : Skin conditioning CAS Number 34406-66-1 COSING REF No: 78761 Chem/IUPAC Name: 1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio) A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. It's also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products. polyglyceryl-10 laurate Rating: GOOD Categories: Emulsifiers, Cleansing Agents, Skin-Softening A plant-derived or synthetic ester of lauric acid and the synthetic polymer polyglycerin-10. Polyglyceryl-10 laurate functions as a skin-softening emulsifier but can also work as a cleansing agent. polyglyceryl-10-laurate is an ester of lauric acid and the synthetic polymer polyglycerin-10. it functions as a skin-softening emulsifier to keep the water and oil components mixed together. it also helps give products a smooth and easy to dispense texture. PG10L-SG| Polyglyceryl-10 Laurate Be the first to review this product Polyglyceryl-10 Laurate aka Durosoft® PG10L-SG is an RSPO segregated Palm Kernel derived oil-in-water emulsifier, perfect for creating creams and lotions with a pleasant and soft skin feel. Common Name : Durosoft®PG10L-SG INCI Name : Polyglyceryl-10 Laurate Origin : U.K. CAS Number : 34406-66-1 EINECS Number : - Description : Polyglyceryl-10 Laurate is naturally derived, from Sunflower, Rapeseed or Caster and RSPO certified segregated Palm Kernel Oil, which is a pale Yellow to Amber coloured liquid. Durosoft PG10L-SG has a mid to high HLB range, an effective cleansing agent recommended for mild rinse off applications. Suggestions for use: This skin and eye friendly cleanser can gently remove make up, dirt and oil from the face and body. Qualities: 100% RSPO Certified Segregated Sustainable Palm Kernel Oil Natural GMO free PEG free Easy to use Skin friendly (Dermatologically tested) HLB range of 11-12 for a greater stability profile Usage 1.0 - 20.0% Better suited for O/W emulsions No deleterious effect on temperature sensitive ingredients Stable water-thin emulsions easily achieved PG10L-SG is an RSPO Segregated oil in water emulsifier, perfect for creating creams and lotions with a pleasant and soft skin feel. It is naturally derived RSPO Segregated palm kernel oil and is an effective cleansing agent recommended for mild rinse off applications particularly facial cleansing products and body washes. This skin and eye friendly cleanser can gently remove make-up, dirt and oil from the face and body. INCI Name Polyglyceryl-10 Laurate China INCI YES Halal Certified RSPO compliant YES JCLN (Japanese) ラウリン酸ポリグリセリル-10 Chemical Name Industry Primarily Used Cosmetics, Pharmaceuticals, Foods, Detergents & Home Care, Inks & Coatings Description Hydrophilic emulsifier; solubilizer Chemical Class Polyglyceryl Fatty Acid Esters CAS Number 34406-66-1 EINECS Appearance Pale yellow to light yellow liquid or petrolatum-like substance HLB 15.5 Package size and type 18kg can Additives NO Tariff Code (H.S. Code) 3402.13 POLYGLYCERYL-10 LAURATE Emulsifier / Emollient / Skin care : This product creates a stable and homogeneous emulsion. It will also smooth and soften the skin, improving the penetration of actives, while maintaining the skin in good condition. The basics on Polyglyceryl-10 Laurate What is Polyglyceryl-10 Laurate? A plant-derived or synthetic ester of lauric acid and the synthetic polymer polyglycerin-10. What are other names for Polyglyceryl-10 Laurate? 4,8,12,16,20,24,28,32,36-NANOXANONATRIACONTANE-1,2,6,10,14,18,22,26,30,34,38,39-DODECOL, DECAGLYCERIN MONOLAURATE, DODECANOIC ACID, MONOESTER WITH, DODECANOIC ACID, MONOESTER WITH DECAGLYCEROL, MONOESTER WITH DECAGLYCEROL DODECANOIC ACID, MONOESTER WITH DODECANOIC ACID, and POLYGLYCERYL-10 LAURATE What is Polyglyceryl-10 Laurate used for? Functions as a skin-softening emulsifier to keep the water and oil components mixed together. it also helps give products a smooth and easy to dispense texture. How Polyglyceryl-10 Laurate is classified Emulsifiers, Cleansing Agents, Skin-Softening Recommendation for Polyglyceryl-10 Laurate in pregnancy and breastfeeding Limited data suggests no known risk General safety info about Polyglyceryl-10 Laurate from CIR The Cosmetic Ingredient Review (CIR) Expert Panel assessed the safety of 274 polyglyceryl fatty acid esters. Each of the esters in this group is a polyether comprising 2 to 20 glyceryl residues, end-capped by esterification with simple carboxylic acids, such as fatty acids. Most of these ingredients are reported to function in cosmetics as skin-conditioning agents and/or surfactants. The Panel reviewed the available data and considered conclusions from relevant previous CIR reports, and determined that these ingredients are safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be non-irritating. INCI Name Polyglyceryl-10 Laurate Extraction Polyglyceryl-10 Laurate is naturally derived, from Sunflower, Rapeseed or Caster and RSPO certified segregated Palm Kernel Oil, which is a pale Yellow to Amber coloured liquid. Durosoft PG10L-SG has a mid to high HLB range, an effective cleansing agent recommended for mild rinse off applications Origin U.K. Qualities 100% RSPO Certified Segregated Sustainable Palm Kernel Oil Natural GMO Free PEG free Easy to use Skin-friendly (Dermatologically tested) HLB range of 11-12 Compatible with both oil and water phases Usage 1.0 - 20.0% Stable water-thin emulsions easily achieved Ingredient Description 1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (10 mol glycerol average molar ratio) polyglycerol-10 laurate cas 34406-66-1 Chemical Name:Polyglycerol-10 Laurate CAS No.: 34406-66-1 Appearance: Light yellow to brown oelic liquid Polyglycerol-10 Polyglycerol-10 LaurateDetails Chemical Name:Polyglycerol-10 Laurate CAS No.: 34406-66-1 MolecularStructure:Polyglycerol-10 Laurate Structure Appearance: Light yellow to brown oelic liquid Polyglycerol-10 LaurateTypical Properties Item Standard Result Appearance Light yellow to brown oelic liquid Qualified Effective Content ≥97.0 98.3 Acid Value(mgKOH/g) ≤ 12 1.7 Saponification Value(mgKOH/g) ≤ 180 48 Iodine (g I2/100g) ≤ 5.0 1.5 Pb (mg/kg) ≤ 2.0 0.1 HLB (Calculation Value) 15~16 15 Polyglycerol-10 LaurateUsage 1.A plant-derived or synthetic ester of lauric acid and the synthetic polymer polyglycerin-10. Polyglyceryl-10 laurate functions as a skin-softening emulsifier but can also work as a cleansing agent. 2.Emulsifiers, Cleansing Agents, Skin-Softening. Emulsifier, solubilizer, dispersant for pharmaceuticalsand foods. 3.It is a natural, PEG-free,and biodegradable ingredient, widely used in cosmetic, food, feed and lubricant, painting, coating, leather, textile and paper etc. 4.A glycerin-derived gentle cleansing agent that is described as being skin and eye-friendly, and not leaving the skin dry or tight. 5.It’s also used as a co-emulsifier or solubilizer that helps to blend small amounts of oily things into water-based products Polyglycerol-10 LauratePackaging and Shipping 25/200KG/Drum Polyglycerol-10 LaurateStorage Sealed and stored in cool dry ventilated warehouse POLYGLYCERYL-10 LAURATE Basic information Product Name: POLYGLYCERYL-10 LAURATE Synonyms: POLYGLYCERYL-10 LAURATE;Dodecanoic acid, monoester with dexaglycerol;Dodecanoic acid,monoester with dexaglycerol;Decaglyceryl monolaurate;Laurate polyglyceryl-10;Polyglycerol-10 Laurate CAS: 34406-66-1 MF: MW: 0 EINECS: Product Categories: Mol File: 34406-66-1.mol Polyglyceryl-10 Laurate Inci name Polyglyceryl-10 laurate French name Polyglyceryl-10 Laurate CAS number. 34406-66-1 EC number. - Other appellations Polyglyceryl-10 laurate What Is It? PEG Dilaurate (PEG-2 Dilaurate, PEG-4 Dilaurate, PEG-6 Dilaurate, PEG-8 Dilaurate, PEG-12 Dilaurate, PEG-20 Dilaurate, PEG-32 Dilaurate, PEG-75 Dilaurate, PEG-150 Dilaurate) and PEG Laurate (PEG-2 Laurate, PEG-2 Laurate SE, PEG-4 Laurate, PEG-6 Laurate, PEG-8 Laurate, PEG-9 Laurate, PEG-10 Laurate, PEG-12 Laurate, PEG-14 Laurate, PEG-20 Laurate, PEG-32 Laurate, PEG-75 Laurate, PEG-150 Laurate) ingredients range from pale yellow, oily liquids to tan, waxy solids. In cosmetics and personal care products, these ingredients are used in the formulation of a wide variety of products, such as shampoos, hair conditioners, personal cleanliness products, bath products, and skin care and skin cleansing products. Why is it used in cosmetics and personal care products? PEG Dilaurate and PEG Laurate ingredients help to form emulsions by reducing the surface tension of the substances to be emulsified. They also clean the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away. INCI: Polyglyceryl -10 Laurate Description This product is a polyglycerol ester made up of an average of 10 glycerol units and lauric acid. Polyglyceryl-10 Laurate is a non-ionic surfactant. It is obtained from natural raw materials. Physical properties It has the appearance of a paste or dense colorless liquid. 70% active ingredient concentration. HLB: ~ 16 Most stable pH range: 4.0 - 8.0 Cosmetic properties It is an emulsifier and viscosity modifier for O / W emulsions. It is a solubilizer of perfumes and essential oils. It has a viscosity reducing effect without influence on stability, ideal for aerosol or roll-on products. It works with or without alcohol. This ingredient is very compatible with the eyes and the skin with a pleasant sensation on the skin. It is not irritating and not sensitizing. It is allowed by ECOCERT. Cosmetic uses It is used as an emulsifying agent, surfactant, and skin conditioner. Also as an alcohol-free solubilizer for perfumes and essential oils. In baby care and facial cleansing products. Leaves a pleasant sensation on the skin. Use concentration Dosage: 1 - 2%. POLYGLYCERYL-10 LAURATE Product Category:surfactants, anionic, cationic, amphoteric, nonionic,solubilisers Product Description:It is a powerful solubilizer and emulsifier. It does not contain peg ingredients, mild properties, will not cause skin irritation, 100% of the raw materials from plants, safe and reliable, is a renewable resource. In addition, it has obtained the EU REACH certification and is widely used in cosmetics and daily chemical industry. The product consists of polyglycerol and lauric acid synthesized from 10 glycerol units, both of which are renewable plant sources. Common Name polyglyceryl-10 laurate CAS Number 34406-66-1 Molecular Weight 941.10300 Density N/A Boiling Point N/A Molecular Formula C42H84O22 Melting Point N/A MSDS N/A Flash Point N/A Polyglyceryl-10 laurate 34406-66-1 2,3-dihydroxypropyl 2,2,3,3,4,4,5,5,6-nonakis(2,3-dihydroxypropyl)dodecanoate Molecular Weight 941.1 g/mol XLogP3-AA -6.1 Hydrogen Bond Donor Count 20 Hydrogen Bond Acceptor Count 22 Rotatable Bond Count 41 Exact Mass 940.545424 g/mol Monoisotopic Mass 940.545424 g/mol Topological Polar Surface Area 431 Ų Heavy Atom Count 64 Formal Charge 0 Complexity 1150 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 11 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 Covalently-Bonded Unit Count 1 Compound Is Canonicalized Yes
POLYGLYCERYL-10 OLEATE
POLYGLYCERYL-10 PENTAOLEATE, N° CAS : 86637-84-5, Nom INCI : POLYGLYCERYL-10 PENTAOLEATE. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI): Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)
POLYGLYCERYL-10 PENTAOLEATE
POLYGLYCERYL-10 STEARATE, N° CAS : 79777-30-3. Nom INCI : POLYGLYCERYL-10 STEARATE. Compatible Bio (Référentiel COSMOS). Ses fonctions (INCI) : Agent d'entretien de la peau : Maintient la peau en bon état
POLYGLYCERYL-10 STEARATE
Octadecanoic acid, 12-hydroxy-, homopolymer, ester with oxybis(propanediol);POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE [INCI]:CN; KE 3190:BN; PGPH:BN; POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE cas no: 156531-21-4
POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE
POLYGLYCERYL-2 LAURATE N° CAS : 96499-68-2 Nom INCI : POLYGLYCERYL-2 LAURATE Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile)
POLYGLYCERYL-2 LAURATE
POLYGLYCERYL-3 METHYLGLUCOSE DISTEARATE; Polyglyceryl-3 distearate; Polyglyceryl-3 distearate [INCI] cas no: 94423-19-5
POLYGLYCERYL-3 CAPRATE
COSING REF No: 78886 Chem/IUPAC Name: 1,2,3-Propanetriol, homopolymer, decanoates (1:1) (3 mol glycerol average molar ratio) Common Name Polyglyceryl-3 Caprate INCI Name Polyglyceryl-3 Caprate Description Polyglyceryl-3 Caprate is a 100% Vegetable derived PEG-free refatting agent for hair and skin cleansing products with excellent thickening properties. It is nitrogen-free and based on polyglycerol. Polyglyceryl-3 Caprate is a surfactant with skin smoothening properties. Origin Germany Suggestions for use When Polyglyceryl-3 Caprate is used in shampoos or shower gels it will increase viscosity. The efficacy profile is similar to that of coco fatty acid ethanol amides but without their disadvantages. Polyglyceryl-3 Caprate is used as a PEG-free re-fatting agent especially in body washes, liquid soaps and bath oils. Polyglyceryl-3 Caprate is a Vegetable derived, PEG-free, refatting agent with excellent thickening properties for shampoos, liquid soaps and bath oils. It helps to provide better and softer skin feel. It can also be used to boost the function of oilymulse to enhance the capability to self-emulsify oil-to-milk products. It has mild antimicrobial effect and de-odorizing effect. Common Name : Polyglyceryl-3 Caprate INCI Name : Polyglyceryl-3 Caprate CAS-Number : 133654-02-1 Origin : Germany Description : Polyglyceryl-3 Caprate is a 100% Vegetable derived PEG-free refatting agent for hair and skin cleansing products with excellent thickening properties. It is nitrogen-free and based on polyglycerol. Polyglyceryl-3 Caprate is a surfactant with skin smoothening properties. Suggestions for use: When Polyglyceryl-3 Caprate is used in shampoos or shower gels it will increase viscosity. The efficacy profile is similar to that of coco fatty acid ethanol amides but without their disadvantages. Polyglyceryl-3 Caprate is used as a PEG-free re-fatting agent especially in body washes, liquid soaps and bath oils. It helps to provide better and softer skin feel. It can also be used to boost the function of oilymulse to enhance the capability to self-emulsify oil-to-milk products. It has mild antimicrobial effect and de-odorizing effect. PC 31 is a PEG-free refatting agent for hair and skin cleansing products with excellent thickening properties. It is nitrogen-free and based on polyglycerol.PC 31 is a surfactant with skin smoothening properties. When used in shampoos or shower gels PC 31 will increase viscosity. The efficacy profile is similar to that of coco fatty acid ethanol amides but without their disadvantages.PC 31 is used as a PEG-free re-fatting agent especially in body washes, liquid soaps and bath oils. Inci name Polyglyceryl-3 caprate French name Polyglyceryl-3 Caprate CAS number. 133654-02-1 EC number. - Other appellations Polyglyceryl-3 caprate Polyglyceryl-3 Caprate Chemical Function: Surfactant Product Applications: Bath & Shower, Clean Beauty, Liquid Soap Green Criteria: Biodegradable , From renewable resources Green Certifications: COSMOS , Ecocert , NaTrue , Whole Foods APPEARANCE Liquid FUNCTION Is a PEG-free, refatting agent with excellent thickening properties for shampoos, liquid soaps and bath oils. It provides a smoothing effect on the skin. SYNONYMS Polyglyceryl-3 Caprate; Tegosoft PC 31; Polyglycerol-3-caprate STORAGE Store in dry, cool area. Keep container closed when not in use. Polyglyceryl-3 Caprate is a 100% Vegetable derived PEG-free refatting agent for hair and skin cleansing products with excellent thickening properties. PRODUCT Polyglyceryl-3 caprate CAS # 133654-02-1 SYNONYM POLYGLYCERYL-3 CAPRATE; Polyglycerol-3-caprate;Polyglyceryl-3 caprate;Decanoic acid, monoester with triglycerol; Triglyceryl monocaprate FORMULA C19H38O8 TYPICAL PRODUCT SPECIFICATIONS NOTES Polyglyceryl-3 caprate is an Ester of capric acid and polyglycerin3 Polyglyceryl-3 caprate uses and applications include: Emulsifier in cosmetics; refatting agent, thickener for shampoos, liquid soaps, bath oils CLASS Specialty Chemicals FUNCTIONS Emulsifier, Acid INDUSTRY Cosmetic Molecular Weight 394.5 g/mol XLogP3 1.5 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 8 Rotatable Bond Count 20 Exact Mass 394.256668 g/mol Monoisotopic Mass 394.256668 g/mol Topological Polar Surface Area 126 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 340 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 3 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 Covalently-Bonded Unit Count 1 Compound Is Canonicalized Yes
POLYGLYCERYL-3 DIISOSTEARATE
Polyglyceryl-3 Diisostearate is a hydroxy compound used as an emollient and surfactant. It finds use in lip glosses and lipsticks especially along with foundations, sunscreens, moisturizers and anti-aging serums. POLYGLYCERYL-3 DIISOSTEARATE is classified as : Emulsifying CAS Number 66082-42-6 / 85666-92-8 EINECS/ELINCS No: - / - COSING REF No: 78891 Chem/IUPAC Name: 1,2,3-Propanetriol, homopolymer, isodecanoates (1:2) (3 mol glycerol average molar ratio) An effective non-ionic emulsifier for Water in Oil formulations. Polyglyceryl-3 diisostearate is exceptionally gentle on the skin and mild, which makes it ideal in products aimed at sensitive skin areas. An effective non-ionic emulsifier for Water in Oil formulations. Polyglyceryl-3 diisostearate is exceptionally gentle on the skin and mild, which makes it ideal in products aimed at sensitive skin areas. The emulsifier is especially versatile during production, being both usable in Hot and Cold Process formulations. Suitable for both skin and hair formulations. Cas Number 66082-42-6 / 85666-92-8 Origin Vegetable derived How to use Blend with other surfactants to produce a foaming product with skin cleansing abilities. Works excellently blended with Cocamidipropyl betaine. Recommended Usage Level 20% -30% oil phase can be emulsified with 4% - 6% Polyglyceryl-3 diisostearate. Stabilisation could be achieved by adding 0.5% - 1% NaCl or 0.5% - 1% MgSO4 Maximum Usage Level None set Products to Use in Moisturising skin care products Conditioning hair treatments Sun protection products Foundations Mascara Lip sticks Precautions No maximum usage level When blending always take the following precautions: Use gloves (disposable are ideal) Take care when handling hot oils Wear eye protection Work in a well ventilated room Keep ingredients and hot oils away from children If ingested, seek immediate medical advice If contact made with eyes, rinse immediately with clean warm water and seek medical advice if in any doubt. Safety First In addition to our precautions and general safety information, we always recommend keeping a first aid kit nearby. You are working with hot water and oils, accidents can happen, so always be prepared! Polyglyceryl-3 Diisostearate and Polyglyceryl-2 Diisostearate are hydroxy compounds used in cosmetics and skin care products as emollients and surfactants, and are found primarily in lip glosses and lipsticks, although they are also seen in foundations, sunscreens, bronzers, moisturizers and anti-aging serums. POLYGLYCERYL-3 DIISOSTEARATE INCI: Polyglyceryl-3 Diisostearate Extraction: It is a natural emulsifiable obtained from glycerin and stearic acid. Benefits: It is used in oily external fase cream formulations and allows to properly emulsify the physical filters in sunscreens. Polyglyceryl-3 Diisostearate is a hydroxy compound used as an emollient and surfactant. It is used in lip glosses and lipsticks especially along with foundations, sunscreens, moisturizers and anti-aging serums. Polyglyceryl-3 Diisostearate Polyglyceryl-3 Diisostearate is a vegetable derived emollient (moisturiser) and emulsifying (prevents separation of oil and water) ingredient; commonly used in lipsticks, sunscreens and moisturisers. INCI: Polyglyceryl-3 Diisostearate Claims: Emulsifiers > Emulsifiers W/O (Water in oil) Applications/Recommended for: Sun care (Sun protection, After-sun & Self-tanning) Skin care (Facial care, Facial cleansing, Body care, Baby care) Recommended use levels: 1.0 - 4.0 %, depending on the application Polyglyceryl-3 Diisostearate CAS No.: 63705-03-3 Appearance: Light yellow liquid Characteristics: Non-ionic water-in-oil emulsifier; Easy emulsification Suitable for water in oil cream/foundation/sunscreen; Application: Cream, lotion etcSkin Care Personal Care Hair Care Sunscreen ........... Use: -Can be added to formulas as is, usual concentration1-3%. Raw Material Source: -Natural and Plan origin -PEG-free -GMO-free -Palm-free Origin: -China Origin Packing: 25kg drum/ 200kg drum Polyglyceryl-3 diisostearate is a Diester of isostearic acid and polyglycerin3 Polyglyceryl-3 diisostearate uses and applications include: Emulsifier, emollient, thickener, solvent in cosmetics, creams, lotions, lip products, pharmaceuticals; dye and pigment wetting agent; food emulsifier; pharmaceuticals excipient. APPEARANCE Clear, yellowish liquid FUNCTION Is used as W/O emulsifier even for cold manufacture. The product is suited for the production of cosmetic emulsions as well as lipophilic sticks and ointments SYNONYMS Polyglyceryl-3 Diisostearate; Lameform TGI, Trigylcerol Distearate; Triglycerine Diisostearate STORAGE Store in sealed original containers, protected from moisture and at temperatures below 30øC. Polyglyceryl-3 Diisostearate may or may not be vegan. It is a compound of Glycerol and Stearic Acid, used in cosmetics as an emulsifier. Stearic Acid can have plant or animal sources. Glycerol is usually derived from plants but sometimes animals. Please check with the manufacturer. An effective emulsifier for Water in Oil formulations. Polyglyceryl-3 diisostearate is exceptionally gentle on the skin and mild, which makes it ideal in products aimed at sensitive skin areas. The emulsifier is especially versatile during production, being both usable in Hot and Cold Process formulations. Suitable for both skin and hair formulations. Conformer generation is disallowed since too many atoms, too flexible.
POLYGLYCERYL-3 DISTEARATE
PEG-4 CAS Number 25322-68-3
POLYGLYCERYL-3 LAURATE
Substance information This ingredient contains polymerized glycerin (as an alcoholic component). The number after "Polyglyceryl-" indicates the average number of glycerine units. Laurates are salts or esters of lauric acid (dodecanoic acid). Function (s) of this ingredient in cosmetic products SURFACTANT (EMULSIFYING) - EMULSIFIER Enables the formation of finely divided mixtures of oil and water (emulsions) Background information on use in cosmetics Emulsifiers are often used as auxiliaries in cosmetics. They make it possible to bring components that are actually immiscible with one another, such as oil and water, into a permanent emulsion. In cosmetic products, both aqueous and oily care and active ingredients can be used in a single product. Emulsifiers are able to do this because their molecules consist of a fat-loving (lipophilic) and a water-loving (hydrophilic) part. This allows you to reduce the interfacial tension that actually exists between two incompatible substances such as fat and water. Emulsifiers are used in particular for creams, lotions and cleaning agents. In the meantime, however, emulsifiers are much more than just auxiliary substances that keep an emulsion stable. Fatty acid esters based on sugar, lecithin or glycerol monodistearate, for example, help to improve the skin's moisture balance and are therefore also considered cosmetic active ingredients. POLYGLYCERYL-3 LAURATE POLYGLYCERYL-3 LAURATE is classified as : Emulsifying CAS Number 51033-31-9 COSING REF No: 78896 Chem/IUPAC Name: 1,2,3-Propanetriol, homopolymer, dodecanoates (1:1) (3 mol glycerol average molar ratio) 5 Formulations containing POLYGLYCERYL-3 LAURATE Sun Care: Very Water Resistant Sun Protective Body Cream - SPF 20Guard your skin against sun damage even in extreme outdoor conditions with this very water-resistant protective cream. Novemer™ EC-2 and Pemulen™ TR-2 Polymers work in combination to provide viscosity, stability as well as a pleasant afterfeel. Pemulen™ TR-2 Polymer also contributes to the water resistance. Hydramol™ TGL and Schercemol™ 105 Esters impart emolliency while SilSense® DW-18 Silicone functions as a skin conditioner. Hair Care: Enriched Hair GlosserAdds shine and tame frizz with this rich, creamy emulsion. Three different esters provide conditioning and gloss without greasiness in this non-silicone formula. Hydramol™ TGL Ester adds emolliency and conditioning to the water phase and serves as a substantive humectant in this product. Baby Care: Daily Kids Protection Cream - SPF 13This cream can protect kids’ sensitive skin from UV radiation and sunburn. This protective cream contains Novemer™ EC-2 and Carbopol® Ultrez 21 Polymers for thickening, stability and afterfeel. The combination of Schercemol™ 105 and Hydramol™ TGL Esters give emolliency as well as a soft, non-sticky afterfeel. Decorative cosmetics: Anti-Aging Eye CreamSchercemol™* LL Ester, which is based on alpha-hydroxy acid, has a low coefficient of friction and therefore imparts this anti-aging cream with a high degree of slip. The emulsion quickly breaks to facilitate targeted delivery, because of the high contact angle low spreading Schercemol™* SHS and DISD Esters. A soft afterfeel leaves the skin feeling elegant throughout the day and collagen extract provides moisturization over long-term use. Toiletries: Shimmery Pomegranate Body PolisherHydramol™* TGL Ester is a water soluble emollient which provides hydration and lasting moisturization in this aesthetically-pleasing body scrub. Hydramol™* PGPD Ester creates a rich, creamy foam. Carbopol®* Ultrez 20 Polymer suspends the exfoliants and effectively thickens in surfactant PRODUCT Polyglyceryl-3 laurate CAS # 51033-31-9 FORMULA C21H42O8; C18H36O6(C3H6O2)n NOTES Polyglyceryl-3 laurate is an Ester of lauric acid and polyglycerin3 Polyglyceryl-3 laurate uses and applications include: Emollient, moisturizer, moisture binder, gloss aid, thickener, softener in colored cosmetics, shampoos, conditioners, bath and shower preparations; gloss aid in lipsticks; thickener, emulsifier in liquid makeup CLASS Specialty Chemicals FUNCTIONS Emulsifier, Acid INDUSTRY Cosmetic Polyglyceryl-3 Laurate What does it do Hydrating, Surfactant, Moisturizer (Emollient), Emulsifying How it works - Ingredient Family N/A Comedogenicity (?) None Polyglyceryl-3 laurate Iupac Name:[3-[3-(2,3-dihydroxypropoxy)-2-hydroxypropoxy]-2-hydroxypropyl] dodecanoate CAS No.:244139-90-0 Molecular Weight:422.6 Molecular Formula:C21H42O8 (isomer) 1. Names and Identifiers 1.1 Synonyms 4,8-Dioxaundecane-1,2,6,10,11-pentol 1-laurate Dodecanoic acid, monoester with 3,3'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(1,2-propanediol) Dodecanoic acid, monoester with triglycerol Hydramol tgl ester Polyglyceryl-3 laurate Polyglyceryl-3 laurate [INCI] SCHEMBL12061389 Sunsoft A-121C Sunsoft A-12C Triglyceryl monolaurate UNII-Y9ZSR39D0E Y9ZSR39D0E 1.2 Inchi InChI=1S/C21H42O8/c1-2-3-4-5-6-7-8-9-10-11-21(26)29-17-20(25)16-28-15-19(24)14-27-13-18(23)12-22/h18-20,22-25H,2-17H2,1H3 1.3 InChkey YYYHDIQLLFHAGW-UHFFFAOYSA-N 1.4 Canonical Smiles CCCCCCCCCCCC(=O)OCC(COCC(COCC(CO)O)O)O 1.5 Isomers Smiles CCCCCCCCCCCC(=O)OCC(COCC(COCC(CO)O)O)O Every emulsion needs at least one emulsifier and when your customers demand natural you have your work cut out! Further, while more and more manufacturers are going down the plant based, non-ethoxylated route not everyone is and with INCI names being complex and technical sounding, it is tempting to just run and hide rather than try out the new stuff. So, before you get the spade ready it’s time to sit back, relax and listen to a little story about polyglyceryl esters – a group of chemicals that may just save your natural formulating life! Q) OK, first explain the name for me please? A) Poly = many and glyceryl = glycerine. Basically this is a polymer (or lots of) glycerine molecules that have been joined together in a way that results in a bigger and more moisturising molecule. It is possible to control not only how long the chain ends up but also where each glycerine joins on (like holding hands). This gives rise to many interesting properties as you will find out if you start using these ingredients. The ester part comes in when you add a fatty acid (e.g.: lauric/ stearic/ oleic) to the polyglyceryl under alkaline conditions. This breaks enough of the internal bonds to enable the two chemicals to join up forming a new molecule which is now called an ester due to the type of bond created. They don’t sound so ‘chemical’ now do they? Q) So what properties do these new ingredients have and why? A) Well, as you know glycerine is water-loving due to its structure and fatty acids contain long tails which are oil loving. Put both of these onto the one molecule and you get something that can marry up both phases of your formulation – otherwise known as an emulsifier! Modifying the fatty acid chain length and/or the polyglyceryl weight changes the emulsification power. On top of that the vast quantity of glycerol functional groups makes these emulsifiers very moisturising and mild to the skin. Q) Are polyglyceryl esters always plant-based? A) Not always as it is possible (but no longer usual) to source both glycerine and fatty acid from animal fats. It is also possible to get both from petroleum and for that reason it is worth asking about the origin of the ingredient before using it – especially if you are making ‘animal/ petroleum free’ claims. Q) Sounds great, so what is so good about Decaglyceryl Monolaurate! A) Decaglyceryl Monolaurate is a non-ionic surfactant with a HLB of 14.8 making it highly water-soluble and therefore good to use as a mild cleaning and degreasing additive. It would also be good to pair up with a lower HLB ingredient (something upwards of HLB 8) as part of an emulsifier for oil in water cream or lotion. Finally it could be used to help solubilise small amounts of oil – say essential oils or fragrances into your water phase (forming a micro-emulsion). Q) You mentioned about pairing it up with another surfactant – what other one would you recommend? A) Well, that would depend quite a bit on your formulation but to give you an example if you were making a mild baby lotion that contained a little oil in water you may want to mix the Decaglyceryl monolaurate with some Sodium Stearoyl Lactylate to ensure that you get a more robust emulsion. As both of these surfactants have a high HLB they will also help to solubilise any fragrance that you have added – including many essential oils. Q) What else are polyglyceryl esters used for? A) They are widely used in the food industry for emulsifying bakery products, keeping chewing gum moist and to replace some fats and are used in the cosmetics and pharmaceutical industry to help hold creams together, modify viscosity of emulsions and disperse and solubilise fragrances and other active ingredients. Overall they are highly regarded due to their mildness, flexibility, moisture holding capacity and biodegradability. They can also be produced sustainably from renewable resources meaning that it won’t just be your skin care product that feels good. Polyglyceryl esters such as those mentioned above can be found in many of your ‘green’ skin care products. Look out for the following INCI names on the label: Polyglyceryl-3 Stearate / Laurate (you can also replace the 3 for another number) Molecular Weight 422.6 g/mol XLogP3 2.6 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 8 Rotatable Bond Count 22 Exact Mass 422.287968 g/mol Monoisotopic Mass 422.287968 g/mol Topological Polar Surface Area 126 Ų Heavy Atom Count 29 Formal Charge 0 Complexity 367 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 3 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 Covalently-Bonded Unit Count 1 Compound Is Canonicalized Yes
POLYGLYCERYL-4 CAPRATE
POLYGLYCERYL-4 CAPRATE is classified as : Emulsifying CAS Number 160391-93-5 COSING REF No: 78907 Chem/IUPAC Name: 1,2,3-Propanetriol, homopolymer, decanoates (1:1) (4 mol glycerol average molar ratio) Details A water-loving emollient that is used as a solubilizer in water-based, toner-like formulas. Solubilizers are handy helper ingredients to dissolve small amounts of oil-loving materials (such as essential oils or fragrances) into watery liquids. Polyglyceryl-4 Caprate also has some emollient properties, making the skin feel nice and smooth. Polyglyceryl-4-caprate is a solubilizer, which blends all formula ingredients into a stable and uniformly dispersed product. It is 100% natural, and derived from rapeseed oil and RSPO-certified sustainable palm oil. Chemical and physical properties • Mixture of nonionic surfactants • Yellowish liquid • Characteristic odor • HLB = 11,5 approx Use guideline • Incorporate it into the water phase • Efficient at low concentration • Can make low viscous and stable O/W emulsions • Suitable for sprayable fluid formulations • Cold processable: ideal for heat-sensitive active ingredients • Easy to handle • Allows the formulation of products with high oil content (up to 80% of Makigreen rice oil) • Use level: 0,1-10% Formulation pH: stable over a pH range of 5,5 to 10,0 • Electrolytes: compatible with NaCl and MgSO4 ,7H2O • Oils: compatible with vegetable and mineral oils, silicone and esters • UV filters: compatible • Pigments: compatible • Treated pigments: compatible with all DAITO’s treatments • Thickeners: compatible with carbomers, xanthan gums, acrylic biopolymers and cellulose derivatives Cosmetic benefits • Provides a pleasant light skin feel • Allows the formulation of rinse-off oil make-up remover which is gentle for the skin and rinse off easily with no oily feel APPEARANCE Clear yellow viscous liquid with a faint odor FUNCTION Is an emulsifier in self-emulsifying oil formulations with elevated water level. It is a PEG-free refatting agent especially for the use in body washes,liquid soaps, bath oils, and wet wipes. SYNONYMS Polyglyceryl-4 Caprate; Polyglycerol-4-caprate; Tegosoft PC 41 STORAGE Store in cool, dry conditions at a temperature between 15øC (59øF). SKU: AC-9193 Categories: Cosmetics, Emulsifiers POLYGLYCERYL-4 CAPRATE Basic information Product Name: POLYGLYCERYL-4 CAPRATE Synonyms: Polyglycerol-4-caprate;POLYGLYCERYL-4 CAPRATE CAS: 160391-93-5 MF: MW: 0 EINECS: Product Categories: Mol File: Mol File Polyglyceryl-4 Caprate Scientific description An ester of oleic acid and polyglycerin-4 What is it Helps keep all the other ingredients together Detailed description Polyglyceryl 4 Caprate is a glycerol derivative and is used in cosmetics as an emulsifying agent. It helps other chemicals to penetrate deeper into the skin and reduces the surface tension of cosmetics. It is organically sourced and valid as a skincare product. This ingredient could be found in products like micellar water, fabric mask, face lotion and toner, shower gel, shampoo, BB cream, baby lotion. What does it do Material Where it comes from Fatty plant or animal acids Product type Plant, Animal, Synthetic Countries of origin Global An ester of Capric Acid and Polyglycerin-4 and a natural emulsifier and solublizer. Polyglyceryl-4 is a skin conditioning agent that has a positive influence on skin structure. Polyglyceryl-4 Caprate is a PEG free and Ecocert approved hydrophilic emollient; it is a surfactant and superfat for detergents and has emulsifying and solubilizing properties. Property Polyglyceryl-4 Caprate is a hydrophilic surfactant belonging to the polyglyceryl family. It does not irritate the skin, is nitrogen-free, therefore it does not contribute to the formation of nitrosamines and has a wide range of cosmetic applications: solubilizers against small percentages of essential oils or lipophilic substances secondary surfactant and superfat in detergents and make-up removers emulsifier in self-emulsifying oily formulations, for example concentrated bath oils that emulsify spontaneously when added to water or anhydrous make-up remover oils primary hydrophilic emulsifier, coupled with a small percentage of a lipophilic emulsifier to lower HLB, to produce cold O / W emulsions Polyglyceryl-4 Caprate is non-degreasing and is well tolerated by the skin, even the sensitive one. Uses Polyglyceryl-4 Caprate can be placed in: cleansing and make-up remover products: shower gel, shampoo, cleansing milks, micellar waters and baby products tonics as a solubilizer self-emulsifying cleaning products cold O / W emulsions (coupled with a lipophilic emulsifier) How to use Recommended use percentage: up to 5% as a secondary surfactant and superfat around 2% as a hydrophilic emulsifier (usually at 20% of the fat phase and in a 1: 4 ratio with the lipophilic emulsifier) indicatively in a 1: 5 ratio with the substance to be solubilized if used as a solubilizer About 1.5% in micellar waters around 15% in self-emulsifying anhydrous cleansing products such as bath oils and make-up remover oils Polyglyceryl-4 Caprate is soluble in water, alcohol and glycols storage Store in a cool and dry place, away from sources of light and heat. INCI Polyglceryl-4 Caprate. Overview Polyglyceryl-4 Caprate is used for Skin conditioning, Skin cleansing and other conditions. This salt may also be used for purposes not listed in this medication guide. Detailed information related to Polyglyceryl-4 Caprate's uses, side-effects, reviews, questions, interactions, and precautions is as follows: Uses Polyglyceryl-4 Caprate is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: Skin conditioning Skin cleansing Polyglyceryl-4 Caprate may also be used for purposes not listed here. Molecular Weight 486.6 g/mol Hydrogen Bond Donor Count 7 Hydrogen Bond Acceptor Count 11 Rotatable Bond Count 22 Exact Mass 486.304012 g/mol Monoisotopic Mass 486.304012 g/mol Topological Polar Surface Area 186 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 317 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 4 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 Covalently-Bonded Unit Count 2 Compound Is Canonicalized Yes
POLYGLYCOL P-1000E
Polyglycol P-1000E is a polyethylene glycol (PEG) with a molecular weight of approximately 1000 g/mol.
Polyglycol P-1000E is a clear, odorless, and viscous liquid that is soluble in water and many organic solvents.

CAS Number: 25322-68-3



APPLICATIONS


Polyglycol P-1000E can be used as a solvent in the production of printing inks.
In the pharmaceutical industry, Polyglycol P-1000E can be used as a carrier for the delivery of active pharmaceutical ingredients.
Polyglycol P-1000E can be used as an emulsifier in the production of personal care products such as creams and lotions.

The lubricant properties of Polyglycol P-1000E make it suitable for use in the production of metalworking fluids.
Polyglycol P-1000E can be used as a humectant in the production of tobacco products.

In the textile industry, Polyglycol P-1000E can be used as a wetting agent and a dyeing auxiliary.
Polyglycol P-1000E can be used as a plasticizer in the production of polyurethane foams.

In the food industry, Polyglycol P-1000E can be used as an anti-foaming agent and a flavor carrier.
The low toxicity of Polyglycol P-1000E makes it suitable for use in the production of pet food.

Polyglycol P-1000E can be used as a dispersant in the production of paints and coatings.
In the agriculture industry, Polyglycol P-1000E can be used as an adjuvant in the formulation of pesticides and herbicides.
Polyglycol P-1000E can be used as a plasticizer in the production of PVC compounds.

In the construction industry, Polyglycol P-1000E can be used as a water-reducing agent in concrete mixtures.
Polyglycol P-1000E can be used as a defoaming agent in the production of paper and pulp.
In the leather industry, Polyglycol P-1000E can be used as a softening agent.

Polyglycol P-1000E can be used as a surfactant in the production of electroplating baths.
In the oil and gas industry, Polyglycol P-1000E can be used as a hydraulic fluid.
Polyglycol P-1000E can be used as a heat transfer fluid in the production of solar panels.

In the mining industry, Polyglycol P-1000E can be used as a flotation agent for the separation of minerals.
Polyglycol P-1000E can be used as a dispersant in the production of ceramics.

In the rubber industry, Polyglycol P-1000E can be used as a processing aid and a softener.
Polyglycol P-1000E can be used as a preservative in the production of cosmetics.

In the water treatment industry, Polyglycol P-1000E can be used as a coagulant aid.
Polyglycol P-1000E can be used as a foam control agent in the production of adhesives.
In the automotive industry, Polyglycol P-1000E can be used as a coolant in engine radiators.

Polyglycol P-1000E is commonly used as a lubricant in the production of polyethylene terephthalate (PET) bottles.
In the textile industry, Polyglycol P-1000E is used as a softener and as a component in dyeing and printing processes.

Polyglycol P-1000E is used as a humectant in personal care products, such as lotions and creams.
Polyglycol P-1000E is used in the production of defoamers for various industrial processes.

Polyglycol P-1000E can be used as a solvent for water-insoluble substances in pharmaceutical applications.
Polyglycol P-1000E is used in the formulation of adhesives and sealants.

In the paper industry, Polyglycol P-1000E is used as a component in paper coatings.
Polyglycol P-1000E can be used as a carrier for active ingredients in agrochemical formulations.
Polyglycol P-1000E is used in the production of brake fluids for automotive applications.

Polyglycol P-1000E is used as a plasticizer in the production of PVC (polyvinyl chloride) products.
In the construction industry, Polyglycol P-1000E is used as a component in grouts and mortars.

Polyglycol P-1000E is used as a processing aid in the production of rubber and elastomers.
Polyglycol P-1000E can be used as a solvent in the extraction of natural products, such as essential oils.

Polyglycol P-1000E is used as a component in the production of heat transfer fluids.
Polyglycol P-1000E is used as a lubricant and release agent in the production of polystyrene foam products.

In the paint and coating industry, Polyglycol P-1000E can be used as a solvent and a viscosity modifier.
Polyglycol P-1000E is used as a coolant and heat transfer fluid in various industrial applications.
Polyglycol P-1000E is used as a component in the production of printing inks and toners.

Polyglycol P-1000E is used as a component in the production of leather and textile finishing agents.
In the mining industry, Polyglycol P-1000E is used as a flotation agent for mineral separation.

Polyglycol P-1000E can be used as a component in the formulation of surfactants and emulsifiers.
Polyglycol P-1000E is used as a humectant and solvent in the production of animal feed.

Polyglycol P-1000E is used as a component in the production of epoxy resins and curing agents.
In the water treatment industry, Polyglycol P-1000E is used as a flocculant for the removal of impurities.

Polyglycol P-1000E is used as a lubricant in the manufacturing of plastics and rubbers.
Polyglycol P-1000E is used as a heat transfer fluid in various industrial applications.
Polyglycol P-1000E is used as a wetting agent in the formulation of agricultural chemicals.

Polyglycol P-1000E is used as a defoaming agent in the production of paper and pulp.
Polyglycol P-1000E is used as a humectant in the cosmetic and personal care industry.

Polyglycol P-1000E is used as a solvent in the production of adhesives and sealants.
Polyglycol P-1000E is used as a surfactant in the production of detergents and cleaners.

Polyglycol P-1000E is used as a carrier solvent in the formulation of paints and coatings.
Polyglycol P-1000E is used as a plasticizer in the manufacturing of vinyl flooring.

Polyglycol P-1000E is used as a hydraulic fluid in the operation of heavy machinery.
Polyglycol P-1000E is used as a coolant in the production of electronic components.
Polyglycol P-1000E is used as a viscosity modifier in the production of personal lubricants.

Polyglycol P-1000E is used as a humectant and emulsifier in the formulation of animal feed.
Polyglycol P-1000E is used as a mold release agent in the production of composite materials.

Polyglycol P-1000E is used as a processing aid in the production of polyurethane foam.
Polyglycol P-1000E is used as a lubricant in the production of metalworking fluids.

Polyglycol P-1000E is used as a corrosion inhibitor in the formulation of antifreeze and coolants.
Polyglycol P-1000E is used as a dispersant in the production of ink and toner.

Polyglycol P-1000E is used as a foam stabilizer in the production of foam products.
Polyglycol P-1000E is used as a humectant and thickener in the formulation of oral care products.
Polyglycol P-1000E is used as a solvent in the production of specialty chemicals.

Polyglycol P-1000E is used as a defoaming agent in the production of food and beverages.
Polyglycol P-1000E is used as a plasticizer and viscosity modifier in the manufacturing of pharmaceuticals.

Polyglycol P-1000E is used as a lubricant and coolant in the production of metal cutting fluids.
Polyglycol P-1000E is used as a wetting agent in the formulation of herbicides and pesticides.

Polyglycol P-1000E is widely used as a lubricant and coolant in metalworking processes.
In the textile industry, Polyglycol P-1000E is used as a dyeing and finishing agent.
Polyglycol P-1000E is a common ingredient in hydraulic fluids and brake fluids due to its high viscosity index.

The high molecular weight of Polyglycol P-1000E makes it an excellent plasticizer in the production of PVC.
As a water-soluble polymer, Polyglycol P-1000E is used as a thickening agent in many personal care products.

Polyglycol P-1000E is a key ingredient in many paints and coatings, providing excellent flow and leveling properties.
In the food industry, Polyglycol P-1000E is used as an emulsifier and stabilizer in many processed foods.

The unique properties of Polyglycol P-1000E make it an ideal ingredient in the production of adhesives and sealants.
Polyglycol P-1000E is commonly used as a surfactant in the production of foams and detergents.
As a low-toxicity, biodegradable chemical, Polyglycol P-1000E is often used as a replacement for more harmful solvents in industrial cleaning applications.



DESCRIPTION


Polyglycol P-1000E is a polyethylene glycol (PEG) with a molecular weight of approximately 1000 g/mol.
Polyglycol P-1000E is a clear, odorless, and viscous liquid that is soluble in water and many organic solvents.

PEGs are a family of synthetic polymers that have a wide range of applications due to their unique properties, such as low toxicity, biocompatibility, and water solubility.
PEGs are used in various industries, including pharmaceuticals, cosmetics, food, and industrial manufacturing, among others.
Polyglycol P-1000E is commonly used as an emulsifier, solubilizer, lubricant, and viscosity modifier.

Polyglycol P-1000E is a water-soluble polymer that is commonly used as a thickening agent.
Polyglycol P-1000E is a type of polyethylene glycol that has a molecular weight of around 1000 g/mol.

Polyglycol P-1000E is a clear, odorless, and colorless liquid that is highly viscous.
Polyglycol P-1000E has a low toxicity and is considered safe for use in various applications.

Polyglycol P-1000E is highly hygroscopic, meaning that it readily absorbs moisture from the environment.
Polyglycol P-1000E is known for its excellent solubility in water, as well as in various organic solvents.

Polyglycol P-1000E has a wide range of viscosity, which can be controlled by adjusting the concentration of the polymer in a solution.
The addition of Polyglycol P-1000E to a solution can improve its stability and prevent the precipitation of certain compounds.

Polyglycol P-1000E is commonly used in the cosmetics industry as a thickener for lotions, creams, and other personal care products.
Polyglycol P-1000E is also used in the food industry as a thickening and stabilizing agent in various products.
Polyglycol P-1000E is often used as a lubricant and anti-foaming agent in the manufacturing of textiles and paper products.

Polyglycol P-1000E is also used in the production of adhesives, sealants, and coatings.
Polyglycol P-1000E is commonly used as a humectant in the formulation of pharmaceutical products.

Polyglycol P-1000E is used as a solvent for various active ingredients in the production of pesticides and herbicides.
Polyglycol P-1000E is also used as a binder in the production of ceramic materials.

Polyglycol P-1000E is highly compatible with various surfactants and can be used to stabilize emulsions.
Polyglycol P-1000E is known for its ability to prevent the precipitation of certain proteins, making it useful in the production of biopharmaceuticals.

Polyglycol P-1000E can also be used as a cryoprotectant, helping to preserve the viability of cells and tissues during freezing and thawing.
Polyglycol P-1000E is highly soluble in alcohol, making it useful in the production of alcoholic beverages.

Polyglycol P-1000E is often used as a viscosity modifier in the production of drilling fluids for oil and gas wells.
Polyglycol P-1000E is also used as a dispersant and emulsifier in the production of paints and coatings.
Polyglycol P-1000E is known for its low toxicity and excellent biocompatibility, making it useful in various medical applications.

Polyglycol P-1000E is commonly used as a lubricant and surfactant in the production of contact lenses and other medical devices.
Polyglycol P-1000E is also used as a humectant in the formulation of various oral care products.
Polyglycol P-1000E is known for its excellent thermal stability and resistance to microbial growth, making it useful in various industrial applications.



PROPERTIES


Chemical formula: C2H4O
Molecular weight: 2000 g/mol
Appearance: Clear liquid
Odor: Odorless
Density: 1.05 g/cm3
Melting point: -60 °C (-76 °F)
Boiling point: 288 °C (550 °F)
Flash point: 154 °C (309 °F)
Solubility: Soluble in water, alcohols, and ketones
pH: Neutral
Viscosity: 1000 cP (centipoise) at 25 °C (77 °F)
Refractive index: 1.449 at 20 °C (68 °F)
Dielectric constant: 32 at 20 °C (68 °F)
Surface tension: 36.5 mN/m (millinewton per meter) at 20 °C (68 °F)
Heat of vaporization: 44.3 kJ/mol
Heat capacity: 2.19 J/(g·K)
Vapor pressure: 0.005 mmHg at 20 °C (68 °F)
Water solubility: 100 g/L at 20 °C (68 °F)
Stability: Stable under normal conditions of use and storage
Reactivity: May react with strong oxidizing agents
Hazardous decomposition products: Carbon monoxide, carbon dioxide
Autoignition temperature: 436 °C (817 °F)
Explosive limits: Lower: 1.4%, Upper: 9.1% (by volume)



FIRST AID


In case of eye contact:

Immediately flush the eyes with plenty of water for at least 15 minutes, while holding the eyelids open to ensure thorough rinsing.
Seek medical attention if irritation or other symptoms persist.


In case of skin contact:

Remove any contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes.
If the skin is burnt, do not remove any clothing that is stuck to the burn, and seek medical attention immediately.
Cover the affected area with a sterile bandage or dressing, if available.


In case of ingestion:

Do not induce vomiting unless directed to do so by medical personnel.
Seek immediate medical attention and provide the medical staff with all relevant information about the substance.


In case of inhalation:

Remove the affected person from the area and take them to an area with fresh air.
If the person has difficulty breathing, seek medical attention immediately.
Administer oxygen or artificial respiration as necessary, if trained to do so.


Other first aid measures:

If there is any possibility of exposure to the substance, wear appropriate personal protective equipment (PPE), including gloves, eye protection, and a respirator.
If Polyglycol P-1000E is spilled or released, contain the spill and prevent it from spreading.
Do not allow the substance to enter drains, waterways, or the environment.
If Polyglycol P-1000E is on fire, use dry chemical, foam, or carbon dioxide extinguishers to put out the fire. Do not use water, as it may spread the fire or cause the substance to react and release hazardous gases.
Seek immediate medical attention if any symptoms or unusual reactions occur, even if they seem minor.



HANDLING AND STORAGE


Handling:

Always wear appropriate personal protective equipment (PPE), such as gloves and eye protection, when handling Polyglycol P-1000E.
Use in a well-ventilated area to avoid inhalation of vapors or mist.

Avoid prolonged or repeated skin contact. In case of skin contact, wash affected area with soap and water.
Do not eat, drink or smoke while handling Polyglycol P-1000E.

Do not use metal containers or utensils to handle or store Polyglycol P-1000E as it may react with some metals.
Follow appropriate procedures to avoid spills and leaks, and dispose of any spilled material properly.
Keep containers tightly closed when not in use to avoid contamination or evaporation.


Storage:

Store Polyglycol P-1000E in a cool, dry, and well-ventilated area.
Keep containers tightly closed to prevent contamination or evaporation.

Store away from heat sources and direct sunlight.
Store away from incompatible materials such as strong oxidizing agents, acids, and bases.
Keep containers off the ground and away from walls to prevent damage or corrosion.

Ensure that storage areas are clearly labeled with appropriate warning signs and information.
Keep storage areas secure and inaccessible to unauthorized personnel, especially children and pets.
Follow all applicable regulations for storage and handling of Polyglycol P-1000E.



SYNONYMS


Polyethylene glycol 1000
Carbowax 1000
PEG 1000
Polyethylene oxide 1000
Poly(oxyethylene) 1000
Polyglycol E-1000
Macrogol 1000
Polyoxyethylene glycol 1000
Polyethylene oxide monomethyl ether 1000
Polyethylene glycol monomethyl ether 1000
Ethylene glycol oligomer 1000
Ethylene oxide homopolymer 1000
Polyethylene oxide monobutyl ether 1000
Polyethylene glycol monobutyl ether 1000
Ethylene glycol polymer 1000
Ethylene glycol homopolymer 1000
Polyethylene glycol dimethyl ether 1000
Polyethylene oxide dibutyl ether 1000
Polyethylene glycol dibutyl ether 1000
Polyethylene oxide distearate 1000
Polyethylene glycol distearate 1000
Polyethylene oxide lauryl ether 1000
Polyethylene glycol lauryl ether 1000
Polyethylene oxide oleate 1000
Polyethylene glycol oleate 1000
Polyethylene glycol 1000 monostearate
PEG 1000 monostearate
PEG 1000 stearate
Polyethylene glycol distearate
PEG distearate
Polyethylene glycol monopalmitate
PEG monopalmitate
Polyethylene glycol dioleate
PEG dioleate
Polyethylene glycol laurate
PEG laurate
Polyethylene glycol oleate
PEG oleate
Polyethylene glycol palmitate
PEG palmitate
Polyethylene glycol stearate
PEG stearate
Polyethylene oxide monostearate
PEO 1000 monostearate
Carbowax 1000 monostearate
POLYGLYKOL 12000 S
H(OCH2CH2)nOH
n = about 272

CAS-No.: 25322-68-3
INCI-designation: PEG-240

Polyglykol 12000 S is a polyethylene glycol that is used for a wide variety of applications including: reactive diol/polyether component in polyester or polyurethene resins; component of auxiliaries for leather and textile processing; cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste); lubricant and mould release agent for rubber, plastic and elastomer processing; plasticizer and binder for ceramic and concrete manufacturing; component of lubricant formulations; water soluble, lubricating component in metalworking fluids; humectant for paper, wood and cellulose films; solvent and humectant for dyes and inks; modifier for production of regenerated viscose; humectant and plasticizer for adhesives; and heat transfer medium.
Polyglykol 12000 S is a flaked type.

Product properties of Polyglykol 12000 S:
Polyglykol 12000 is a white waxy solid at room temperature.
Polyglykol 12000 S is a flaked type, Polyglykol 12000 P a powdered type available in 20 kg (S), 25 kg (P) bags or super sacs with up to 500 kg capacity.
Polyglykol 12000 S's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 12000.

Therefore Polyglykol 12000 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 12000 is insoluble in pure hydrocarbons.
Polyglykol 12000 displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 12000 is about 58°C.

Storage of Polyglykol 12000 S:
When Polyglykol 12000 S is stored in a cold, dry place in a closed container Polyglykol 12000 S and 12000 P can be kept for at least two years.

Applications of Polyglykol 12000 S:
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Fields of applications of Polyglykol 12000 S:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or plasticiser for creams, tablets, tooth paste)
- Lubricant and mould release agent for rubber, plastic and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metalworking fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives

Polyglykol 12000 S is a solubilizer, binder, thickener and moisturizing agent.
Polyglykol 12000 S offers low toxicity and no emulsifying effect.
Polyglykol 12000 S possesses binding, softening and non-irritating properties.
Polyglykol 12000 S is used in lotions, creams and hair styling products.

Benefits of Polyglykol 12000 S:
Good solubility in water
Very low water content
Compatible with hard water
Non-volatile
Outstanding toxicological safety

Chemical Name:
PEG-240

Product Function:
Humectant

Chemical Type:
Polyethylene glycol

Applications of Polyglykol 12000 S:
Hair Conditioner
Hair Styling
Performance Claims
Water-soluble
Moisturizing
Anti-perspirant
Conditioning

PEG-240. Polyglykol 12000 S is a solubilizer, binder, thickener and moisturizing agent.
Polyglykol 12000 S offers low toxicity and no emulsifying effect.

Polyglykol 12000 S possesses binding, softening and non-irritating properties.
Polyglykol 12000 S is used in lotions, creams and hair styling products.
Polyglykol 12000 S is a slip and mould release agent, solubilizer, carrier substance, softener, auxilliary for tablet manufacture, binding agent.

Product data:
water content (DIN 51777) % m/m max. 0.5
colour index [APHA] (EN 1557) (25 % in water) max. 30
pH ( 5 % w/w in water) (DIN EN 1262) 5 – 7
hydroxyl number (DIN 53240) mg KOH/g 7.5 – 11
molecular weight g/mol 10500 – 15000
solidification point (EP III) °C 55 – 60
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas 1100 – 1400
flash point (DIN 51376) °C 245
ignition temperature (DIN 51794) °C >320
ethyleneoxid ppm max. 1
dioxane ppm max. 1

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
It is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
It is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
It is suitable for paints and coatings.
The shelf life of this product is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
It is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
It is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
It is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
This grade possesses very low water content and good solubility in water.
It is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
It is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
It possesses low melting range, very low water content and excellent solubility in water.
This grade is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
It retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This product prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
It is used in water-based and solvent-borne alkyd end-use pigment preparations.
It retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
It possesses very low water content and excellent solubility in water.
This grade is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
It is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
It is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
It possesses very low water content and excellent solubility in water.
This grade is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
It shows very low water content and good solubility in water.
This grade is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
It possesses very low water content and good solubility in water.
This grade is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
It shows very low water content and good solubility in water.
This grade is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
It is suitable for paint additive manufacturing.
The shelf life of this product is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
It displays moderate enhancement of hydrophilicity.
This product also enhances material- and biocompatibility of polymers.
It is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
It enhances hydrophilicity with increasing chain length.
This product also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
It enhances hydrophilicity with increasing chain length.
This product also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
It enhances hydrophilicity with increasing chain length.
This product also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
It is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
It is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
It is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
It offers lower preparation viscosities compared with conventional linear Polyglykols, low VOC-content and little impact on wet scrub resistance at usual charges.
It retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
It is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
It is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
It is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
It is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
It contains low content of diol contaminants.
This product possesses narrow molecular weight distribution.
It is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
It possesses low content of diol contaminants.
This product is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
It is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
It offers low alkali and low water content.
This grade is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
It is used in paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
It is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Acts as a humectant, solvent, and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Acts as a plasticizer, solvent and humectant.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
It is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Its recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
It is Ecolabel compliant.
It is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol.
It slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
It is used as humectants, retention agent and solvent in waterborne pigments.
It is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
It is soluble in water and polar organic solvents like acetone or methanol.
It is insoluble in pure hydrocarbons.
It is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
It is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
It has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
It acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
It is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
It is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
It is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 1500 FL
CAS: 25322-68-3
INCI: PEG-32

Auxiliary for the detergent industry

Composition: Polyethylene glykol with 34 mol EO

Polyglykol 1500 FL is a polyethylene glycol with a mean molecular weight of 1500.
Polyglykol 1500 FL is a pasty PEG excipient grade product, produced under IPEC GMP conditions.

Polyglykol 1500 FL is a polyethylene glycol white waxy solid at room temperature.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL displays typical chemical reactions of alcohols/diols.

Polyglykol 1500 FL is a solvent, release agent, lubricant and plasticizer.
Polyglykol 1500 FL is polyethylene glycol available in yellowish colored liquid form.
Polyglykol 1500 FL contains reduced amounts of residual alkali and water.

Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is compatible with cellulose, polyester, rubber, elastomer and polyurethane.

Benefits of Polyglykol 1500 FL:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety
-Good biodegradability

INCI Name: PEG-32
Function: Binder, Humectant, Carrier, Moisturizing Agent
CAS Number: 25322-68-3
Dosage Form: Ointments
Ingredient Origin: Synthetic
Certifications & Compliance: CosIng Listed, REACH (Europe)

Applications & Uses of Polyglykol 1500 FL:
Markets:
-HI&I Care
-Healthcare & Pharma
-Personal Care

Applications of Polyglykol 1500 FL:
Personal Care — Beauty & Care:
-AP/Deo
-Bath & Shower
-Color Cosmetics
-Hair Care
-Skin Care
-Sun Care

Healthcare & Pharma — Drug Delivery & Care Solutions:
-Topical

HI&I Care — Home Care:
-Dish Care
-Laundry & Fabric Care

Personal Care — Personal Hygiene:
-Hand Hygiene

Application Format of Polyglykol 1500 FL:
-Bar
-Creams
-Gel
-Leave On
-Lotions
-Rinse Off
-Roll On
-Spray

Dosage Form:
-Ointments

AP/Deo Applications of Polyglykol 1500 FL:
-Antiperspirants & Deodorants

Bath & Shower Applications of Polyglykol 1500 FL:
-Bar Soaps
-Body Wash & Cleanser
-Bubble Bath
-Liquid Soap

Color Cosmetic Applications of Polyglykol 1500 FL:
-BB Creams
-Eye Liner

Hair Care Applications of Polyglykol 1500 FL:
-Hair Spray
-Hair Styling Products
-Shampoos & Rinses

Home Care Applications of Polyglykol 1500 FL:
-Bar Soaps

Personal Hygiene Applications of Polyglykol 1500 FL:
-Hand Soap
-Liquid Hand Soap

Skin Care Applications of Polyglykol 1500 FL:
-Facial Cleanser

Sun Care Applications of Polyglykol 1500 FL:
-After Sun Products

Product properties of Polyglykol 1500 FL:
Concentration [%]: approx. 100
Relative molar mass [Dalton]: 1400 - 1600
Appearance: wax
Delivery form: melt
Hazen colour, 25% in water: max. 30
Solidification point [°C]: 44 - 48
Hydroxyl number [mg KOH/g]: 70 – 80
Viscosity, 20°C, 50% in water [mPas]: 36 - 42
Water (Karl Fischer method) [%]: max. 0.1
pH value, 5% in water: 5.0 – 7.0
Oxide ash [%]: max. 0.05
Solubility in water: dissolves to a clear solution

Product Function:
-Moisturizer

Chemical Name:
-Polyethylene glycol, average molar mass 1500 g/mol

Applications of Polyglykol 1500 FL:
Washing and cleaning agents in liquid and paste form, wash and soil release aids, dispersants and gelling agents, auxiliaries for spray granulation.

Pharmacopoeia Name:
USP-NF: Polyethylene glycol 1500, Ph. Eur.: Macrogol 1500

Physical appearance of Polyglykol 1500 FL:
-Paste

Quality status:
-Excipient, IPEC GMP; Kosher certificate

Application function of Polyglykol 1500 FL:
Humectant, Solvent, Ointment base

Identification & Functionality of Polyglykol 1500 FL:
Chemical Family:
-Polyethylene Glycols
-Polyglycols
-Polyols

Chemical Name:
PEG 1500

INCI Name:
PEG-32

Ingredient Origin:
Synthetic

Cleaning Ingredients Functions:
Binder

Cosmetic Ingredients Functions:
-Binder
-Humectant
-Moisturizing Agent

Pharma & Nutraceuticals Functions:
-Carrier

CAS No.: 25322-68-3

Technologies:
-Cleaning Ingredients
-Cosmetic Ingredients
-Pharmaceuticals & Nutraceuticals

Product Families:
-Pharmaceuticals & Nutraceuticals — Excipients:
-Carriers & Bulking Agents

Cleaning Ingredients — Functional Additives:
-Performance Additives

Cosmetic Ingredients — Functionals:
-Conditioners & Emollients
-Texturizers & Fillers

Polyglykol 1500 FL Features & Benefits
Benefit Claims:
-Humectancy
-Moisturizing
-Softening

Labeling Claims:
-Biodegradable

HII Features:
-Humectancy

Product Highlights:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety
-Good biodegradability

Recommended Uses of Polyglykol 1500 FL:
-Washing and cleaning agents in liquid and paste form
-wash and soil release aids
-dispersants and gelling agents,
-auxiliaries for spray granulation

Properties of Polyglykol 1500 FL:
-Physical Form:
-Liquid

Appearance of Polyglykol 1500 FL:
-Wax

Polyglykol 1500 FL is soluble in:
-Water

Storage of Polyglykol 1500 FL:
Polyglycol 1500 FL can be stored for at least to 2 years in original sealed containers at room temperature under the recommended conditions.
Polyglycol 1500 FL undergoes no change whatever in It's product properties when exposed to cold during transport and storage.

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear polyglycols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
Polyglykol 1500 PS
SYNONYMS PEG; Macrogol; Polyoxyethlene; Aquaffin; Nycoline; alpha-hydro-omega-hydroxypoly(oxy-1,2-ethanediyl); polyethylene glycols; Poly Ethylene Oxide; Polyoxyethylene; Polyglycol; 1,2-ethanediol Ehoxylated; Polyoxyethylene ether; Polyoxyethylene; Poly(ethylene glycol); CAS NO. 25322-68-3
Polyglykol 1500 S
PEG; Polyglycol; Polyethylene oxide; Polyoxy ethylene; Polyethylene Glycol 200; Polyethylene Glycol 400; Polyethylene Glycol 300; Polyethylene Glycol 600; Polyethylene Glycol 1500; Polyethylene Glycol 4000; Polyethylene Glycol 8000; Polyethylene Glycol 6000; CAS NO: 25322-68-3
Polyglykol 200
PEG-6 ,PEG-6;Hexaethylene glycol; PEG 300; 3,6,9,12,15-Pentaoxaheptadecane-1,17-diol; Polyethylene glycol 300 cas :2615-15-8
Polyglykol 300
PEG-75 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (75 mol EO average molar ratio) CAS Number 25322-68-3
Polyglykol 3000
Octadecanoic acid, 12-hydroxy-, homopolymer, ester with oxybis(propanediol);POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE [INCI]:CN; KE 3190:BN; PGPH:BN; POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE cas no: 156531-21-4
POLYGLYKOL 3000 P
Polyglykol 3000 P is a white waxy solid powdered type polyethylene glycol at room temperature.
Polyglykol 3000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3000 P is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.

CAS Number: 25322-68-3

Polyglykol 3000 P provides low toxicity and no emulsifying effect.
Polyglykol 3000 P shows very low water content and compatible with hard water.
Polyglykol 3000 P is used in skin-care products.

Polyglykol 3000 P is a liquid polyalkylene glycol used as an antifoam agent in a wide variety of industries, including latex formulations, paper and pulp processing, emulsion paints, and food production.
Polyglykol 3000 P is a multi-purpose cosmetic material that is used as a slip agent and mold release agent, solvent, carrier, concentrate and antistatic agent in skin care products.

Polyglykol 3000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions.
The powder form of Polyglykol 3000 P supports the homogeneous mixing with other materials within production.

Polyglykol 3000 P is specified according to the requirements of the main international ICH guidelines and monographs.
Polyglykol 3000 P offers softening, binding and non-irritating properties.

Polyglykol 3000 P is a milled PEG excipient grade powder product, produced under IPEC GMP conditions.
The powder form supports the homogeneous mixing with other materials within production.
Polyglykol 3000 P is specified according to the requirements of the main international ICH guidelines and monographs.

Polyglykol 3000 P is a white waxy solid powdered type polyethylene glycol at room temperature.
Polyglykol 3000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3000 P is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.

Polyglykol 3000 P is a non-volatile slip, solubilizer, carrier, thickener and anti-static agent.
Polyglykol 3000 P offers softening, binding and non-irritating properties.

Polyglykol 3000 P provides low toxicity and no emulsifying effect.
Polyglykol 3000 P shows very low water content and compatible with hard water.
Polyglykol 3000 P is used in skin-care products.

Polyglykol 3000 P is a liquid polyalkylene glycol used as an antifoam agent in a wide variety of industries, including latex formulations, paper and pulp processing, emulsion paints, and food production.
Polyglykol 3000 P is a PO homopolymer triol with a 3000 molecular weight, used in a range of foam control applications.

Polyglykol 3000 P is a white waxy solid powdered type polyethylene glycol at room temperature.
Polyglykol 3000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3000 P is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.

Polyglykol 3000 P is used in skin care.
Polyglykol 3000 P is acts as a slip and mold-release agent, solubilizer, carrier, thickener and antistatic agent.

Applications of Polyglykol 3000 P:
Polyglykol 3000 P is based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Polyglykol 3000 P Fields of Applications:
Reactive diol/polyether component in polyester or polyurethene resins
Component of auxiliaries for leather and textile processing

Cosmetic / pharmaceutical formulations (e.g. humectant or plasticiser for creams, tablets, tooth paste)
Lubricant and mould release agent for rubber, plastic and elastomer processing

Plasticizer and binder for ceramic and concrete manufacturing
Component of lubricant formulations

Water soluble, lubricating component in metalworking fluids
Humectant for paper, wood and cellulose films

Solvent and humectant for dyes and inks
Modifier for production of regenerated viscose
Humectant and plasticizer for adhesives

Uses of Polyglykol 3000 P:
Foam Control
Boiler Systems
Process Treatments
Fiber and textile processing
Food and fermentation
Kosher applications
Paper processing
Personal care
Plastics
Water and wastewater treatment
Chemical intermediates
Foam control
Heat transfer fluids
Industrial surfactants
Synthetic lubricants

Uses Area of Polyglykol 3000 P:
Additives - Anti-static Agents
Solvents - Glycols Glycol Ethers - Ethylene Glycol
Additives - Reaper
Additives - Atomization Additives
Lubricants Additives
Rheology Thickeners Additives
Slip Control Agents

Benefits of Polyglykol 3000 P:
Low pour points
Wide range of hydrophile-lipophile balances and molecular weights
Expand formulating possibilities
Excellent lubricity and solvency

Advantages of Polyglykol 3000 P:
Posesses binding
Softening and non irritating properties
Offers low toxicity
No emulsifying effect
Skin care (Facial care, Facial cleansing, Body care, Baby care)

Properties of Polyglykol 3000 P:
Polyglykol 3000 P is a white waxy solid at room temperature.
Polyglykol 3000 P can be supplied in heated tank trucks.

Polyglykol 3000 is a flaked type, Polyglykol 3000 P a powdered type available in 20 kg bags or super sacs with up to 500 kg capacity.
Polyglykol 3000 P's two hydroxy end groups as well as Polyglykol 3000 P ether groups mainly control the physical and chemical properties of Polyglykol 3000.

Therefore Polyglykol 3000 P is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 3000 P is insoluble in pure hydrocarbons.

Polyglykol 3000 P displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 3000 P is about 54 °C.

Storage of Polyglykol 3000 P:
When stored in a cold, dry place in a closed container Polyglykol 3000 S and 3000 P can be kept for at least two years.

Stability and Reactivity of Polyglykol 3000 P:

Chemical stability:
Stable under normal conditions.

Possibility of hazardous reactions:

Hazardous reactions:
No dangerous reaction known under conditions of normal use.

Conditions to avoid:
Keep away from heat and sources of ignition.

Incompatible materials:

Materials to avoid:
not known.

Hazardous decomposition products:
When handled and stored appropriately, no dangerous decomposition products are known.

Handling and Storage of Polyglykol 3000 P:

Advice on safe handling:
Avoid the formation and deposition of dust.
Avoid dust formation.

Avoid dust accumulation in enclosed space.
Provide adequate ventilation.

Advice on protection against fire and explosion:
Keep away sources of ignition.
Take precautionary measures against build-up of electrostatic charges, e.g earthing during loading and off-loading operations.
Dust can form an explosive mixture in air.

Hygiene measures:
Observe the usual precautions for handling chemicals.

Conditions for safe storage, including any incompatibilities:

Requirements for storage areas and containers:
Keep only in the original container.

Further information on storage conditions:
Keep containers tightly closed in a cool, well-ventilated place.

Specific end use(s)

Specific use(s):
No further recommendations.

First Aid Measures of Polyglykol 3000 P:

General advice:
Remove/ Take off immediately all contaminated clothing.
Get medical advice/ attention if you feel unwell.

If inhaled:
If inhaled, remove to fresh air.
Get medical advice/ attention.

In case of skin contact:
If on skin, rinse well with water.

In case of eye contact:
In case of contact, immediately flush eyes with plenty of water for at least 15 minutes.

If swallowed:
No special measures necessary.

Most important symptoms and effects, both acute and delayed:

Symptoms:
No symptoms known currently.

Risks:
No hazards known at this time.

Indication of any immediate medical attention and special treatment needed:

Treatment:
Treat symptomatically.

Firefighting Measures of Polyglykol 3000 P:

Suitable extinguishing media:
Water spray jet
Dry powder
Foam
Carbon dioxide (CO2)

Special hazards arising from the substance or mixture:

Specific hazards during firefighting:
In case of fires, hazardous combustion gases are formed:
Carbon monoxide (CO)
Carbon dioxide (CO2)

Advice for firefighters:

Special protective equipment for firefighters:
Self-contained breathing apparatus.

Accidental release measures of Polyglykol 3000 P:

Personal precautions:
Wear suitable protective equipment.
Ensure adequate ventilation.

Environmental precautions:
Polyglykol 3000 P should not be allowed to enter drains, water courses or the soil.

Methods and material for containment and cleaning up:

Methods for cleaning up:
Take up mechanically.

Identifiers of Polyglykol 3000 P:
Trade name
POLYGLYKOL 3000 S
Material number: 107911
Chemical nature: polyethylene glycol, HO-(CH2-CH2-O)n-H, average molecular
mass 3000
INCI name: PEG-60
CAS number: 25322-68-3

CAS-No.: 25322-68-3
INCI-designation: PEG-60

Physical and Chemical Properties of Polyglykol 3000 P:
Physical state: flakes
Colour: white
Odour: characteristic
Odour Threshold: not tested.
Freezing point: 52 - 56°C
Flash point: 270 °C
Auto-ignition temperature: > 320°C
Decomposition temperature: 360°C
pH: 5 - 7 (20°C)
Concentration: 100 g/l
Viscosity:
Viscosity, dynamic: 75 - 100 mPa.s (20°C)
Viscosity, kinematic: 69 - 92 mm2/s (20°C)
Solubility(ies):
Water solubility: approx. 500 g/l (20 °C)
Solubility in other solvents: Solvent: fat not tested.
Partition coefficient: noctanol/water: log Pow: < -1
Vapour pressure: < 0.01 mbar (20 °C)
Density: approx. 1.2 g/cm3 (20 °C)
Bulk density: 400 - 500 kg/m3
Particle characteristics

Water content % m/m:
Max. 0.5
Max. 0.1 (FL–type)
Colour index (25 % in water): max. 30
pH (5 % w/w in water): 5 – 7
Hydroxyl number mg KOH/g: 34 – 42
Molecular weight g/mol: 2700 – 3300
Solidification point °C: 52 – 56
Viscosity at 20°C (50 % w/w in water) mPas: 75 – 95
Flash point °C: 260
Ignition temperature °C: >320
Ethylene oxide ppm: max. 1
Dioxane ppm: max. 1

Other Descriptions of Polyglykol 3000 P:

Chemical Name:
Polyethylene glycol, average molar mass 3000 g/mol

Pharmacopoeia Name:
USP-NF: Polyethylene glycol 3000, Ph.Eur.: Macrogol 3000

Physical appearance:
Powder, milled

Quality status:
Excipient, IPEC GMP; Kosher certificate

Application function:
Solvent, Coating agent, Binder

Composition:
Polyethylene glycol
H(OCH2CH2)nOH
n = about 68

Industry:
Makeup

Other Polyglykol Products:
Polyglykol 1000
Polyglykol 1000 SG VITA
Polyglykol 10000 S
Polyglykol 10000 SG
Polyglykol 12000 S
Polyglykol 1500 FL PU
Polyglykol 1500 S
Polyglykol 2000 PU
Polyglykol 2000 S
Polyglykol 300
Polyglykol 400
Polyglykol 4000 S
Polyglykol 600
Polyglykol 600 PU
Polyglykol 6000 P
Polyglykol 8000 P
Polyglykol 8000 S
Polyglykol 9000 S
Polyglykol AM 1100
Polyglykol AM 250
Polyglykol AM 450
Polyglykol D 21/150
Polyglykol D 21/300
Polyglykol D 21/700
Polyglykol G 500
Polyglykol M 1000
Polyglykol M 2000 FL
Polyglykol M 2000 S
Polyglykol M 350
Polyglykol M 350 PU
Polyglykol M 500
Polyglykol M 500 PU
Polyglykol M 750
Polyglykol M 750 PU
Polyglykol 10000 FL
Polyglykol 1500 FL
Polyglykol 1500 PS
Polyglykol 200 LVC
Polyglykol 2000 FL
Polyglykol 3400 FL
Polyglykol 3400 PS
Polyglykol 4000 PS
Polyglykol 4000 FL
Polyglykol 4000 M50
Polyglykol 4000 P
Polyglykol 4000 PF
Polyglykol 4000 PSK
Polyglykol 6000 FL
Polyglykol 6000 PF
Polyglykol 6000 PS
Polyglykol 8000 FL
Polyglykol 8000 PF
Polyglykol 8000 PS
Polyglykol 9000 FL
Polyglykol A 11/1800
Polyglykol A 32/550
Polyglykol A 400
Polyglykol A 500
Polyglykol PR 600

Syonyms of Polyglykol 3000 P:
2-(2-hydroxypropoxy)propan-1-ol
POLYPROPYLENE GLYCOL
C6H14O3
Polypropylene glycol
Polyoxypropylene
Emkapyl
Poly(propylene oxide)
Polyoxypropylene glycol
2-(2-hydroxypropoxy)propan-1-ol
Lineartop E
Niax ppg
Methyloxirane homopolymer
Polymer 2
Propylene oxide homopolymer
Desmophen 360C
2-(2-HYDROXYPROPOXY)-1-PROPANOL
Polyglycol P 400
Pluracol 1010
Pluracol 2010
Pluracol P 410
Propylan 8123
Caswell No. 680
Glycols, polypropylene
Niax ppg 425
Pluracol P 2010
Jeffox PPG 400
Polyglycol P-2000
Polyglycol P-4000
Voranol P 1010
Voranol P 2000
Voranol P 4000
Laprol 2002
Niax ppg 1025
Niax ppg 3025
Polyglycol type P250
Polyglycol type P400
Polyglycol type P750
Alkapal PPG-1200
Alkapal PPG-2000
Alkapal PPG-4000
Actocol 51-530
Napter E 8075
Niax polyol ppg 4025
P 4000 (polymer)
Polyglycol type P1200
Polyglycol type P2000
Polyglycol type P3000
Polypropylenglykol [Czech]
Niax 1025
Oopg 1000; Polypropylene glycol #400
Polypropylene glycol #425
Polypropylene glycol #750
Polypropylene glycol 1025
Polypropylene glycol 2000
Niax 11-27
PPG-9
1-Propanol, 2-(2-hydroxypropoxy)-
Polypropylene glycol #1200
Niax 61-582
Oxirane, methyl-, homopolymer
PPG-12
PPG-15
PPG-17
PPG-20
PPG-26; PPG-30
PPG-34
Propylene oxide, propylene glycol polymer
Laprol 702
Polyoxypropylene (9)
alpha-Hydro-omega-hydroxypoly(oxypropylene)
HSDB 1266
Polyoxypropylene (12)
Polyoxypropylene (15)
Polyoxypropylene (17)
Polyoxypropylene (20)
Polyoxypropylene (26)
Polyoxypropylene (30)
Polyoxypropylene (34)
LUBRIMET P600, P900
PLURACOL
P410, P1010, P2010, P4010 Pluriol
P600, P2000, Polyglycol P425, P1200, P2000, P4000 Polypropylene glycol (9)
Polypropylene glycol 150
EPA Pesticide Chemical Code 068602; P.P.G 2025
POLYGLYKOL 3350
Polyglykol 3350 S
Polyglykol 3350 PB
Polyglykol 3350 PS
Polyglykol 3350 PF
Polyglykol 3350 FL
Polyglykol 3350 P

Composition:
Polyethylene glycol

H(OCH2CH2)nOH
n = about 76

CAS-No.: 25322-68-3
INCI-designation: PEG-75

Polyglykol 3350 P is a polethylene glycol with a mean molecular weight of 3350.
Polyglykol 3350 is a solid in powder form.

Benefits of Polyglykol 3350:
-Excellent solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety

Product Functions of Polyglykol 3350:
-Moisturizer
-Solublizers
-Binders

Product properties of Polyglykol 3350:
Polyglykol 3350 is a white waxy solid at room temperature.
Polyglykol 3350 FL can be supplied in heated tank trucks.
Polyglykol 3350 S is a flaked type, Polyglykol 3350 P, 3350 PS, 3350 PF, 3350 PB are powdered types available in 20 kg bags or super sacs with up to 500 kg capacity.

Its two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 3350.
Therefore Polyglykol 3350 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 3350 is insoluble in pure hydrocarbons.

Polyglykol 3350 displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 3350 is about 55°C.

Polyglykol 3350 PS is polyethylene glycol, supplied as a white powder.
Polyglykol 3350 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3350 has a wide range of applications across several industries for its excellent properties as a solvent, humectant, and plasticizer.

Polyglykol 3350 PB is a polyethylene glycol that is used for a wide variety of applications including: reactive diol/polyether component in polyester or polyurethene resins; component of auxiliaries for leather and textile processing; cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste); lubricant and mould release agent for rubber, plastic and elastomer processing; plasticizer and binder for ceramic and concrete manufacturing; component of lubricant formulations; water soluble, lubricating component in metalworking fluids; humectant for paper, wood and cellulose films; solvent and humectant for dyes and inks; modifier for production of regenerated viscose; humectant and plasticizer for adhesives; and heat transfer medium.
Polyglykol 3350 PB is a powdered type, and it has a molecular weight of 3050 – 3685g/mol.

Polyglykol 3350 S Polethylene Glycol is a polethylene glycol with a mean molecular weight of 3350.
Polyglykol 3350 is a solid in flake form.

INCI Name: PEG-75
Function: Solubilizer, Thickener, Solvent, Ointment Base, Plasticizer, Moisturizing Agent, Anti-Static Agent, Binder, Humectant, Viscosity Modifier, Carrier, Slip Agent
CAS Number: 25322-68-3
Dosage Form: Ointments
Ingredient Origin: Synthetic

Polyglykol 3350 PSN is a polethylene glycol with a mean molecular weight of 3350.

Chemical Name: PEG 3350
CAS Number: 25322-68-3
Function: Binder
Manufacturing Technology: Granulation

PEG-75.
Polyglykol 3350 P is non-volatile, slip and mold-release agent, solubilizer, thickener and anti-static agent.
Polyglykol 3350 offers non-irritating, binding and softening properties.
Polyglykol 3350 provides low toxicity and no emulsifying effect.

Polyglykol 3350 offers very low water content and is compatible with hard water.
Polyglykol 3350 is also used as a binder in bath salts and denture cleaners.
Polyglykol 3350 is used in skin-care products.
Polyglykol 3350 has a shelf life of 2 years.

Storage of Polyglykol 3350:
When Polyglykol 3350 is stored in a cold, dry place in a closed container Polyglykol 3350 S, 3350 P, 3350 PS, 3350 PF and 3350 PB can be kept for at least two years.

Applications of Polyglykol 3350:
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Fields of applications of Polyglykol 3350:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or plasticiser for creams, tablets, tooth paste)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metalworking fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives

Product data of Polyglykol 3350:
water content (DIN 51777) % m/m max. 0.5
max 0.1 (FL-Type)
colour index [APHA] (EN 1557) (25 % in water) max. 30
pH ( 5 % w/w in water) (DIN EN 1262) 5 – 7
hydroxyl number (HOE 06 HB 0211) mg KOH/g 30 – 37
molecular weight g/mol 3050 – 3685
solidification point (EP III) °C 53 – 57
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas 85 – 100
flash point (DIN 51376) °C 260
ignition temperature (DIN 51794) °C >320
ethylene oxide ppm max. 1
dioxane ppm max. 1

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear polyglycols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 3350 P
PEG-75 Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (75 mol EO average molar ratio) CAS Number 25322-68-3
Polyglykol 3350 P
Binder for dishwashing and laundry tabs and multi-phase products. Polyethyleneglykol ; cas no : 25322-68-3 ; Flakes ; 100%
Polyglykol 3350 PS
PEG-4 CAS Number 25322-68-3
Polyglykol 3350 S
PEG-8 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (8 mol EO average molar ratio) CAS Number 5117-19-1 / 25322-68-3 (generic)
POLYGLYKOL 350
Composition:
Polyethylene glycol

H(OCH2CH2)nOH
n = about 8

CAS-No.: 25322-68-3

Product properties of Polyglykol 350:
Polyglykol 350 is clear viscous liquid at room temperature.
Polyglykol 350 can be supplied in tank trucks or in steel drums.
Polyglykol 350's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 350.

Therefore Polyglykol 350 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 350 is insoluble in pure hydrocarbons.

Polyglykol 350 displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 350 is about 0°C.

Storage of Polyglykol 350:
When stored in a cold, dry place in a closed container Polyglykol 350 can be kept for at least two years.

Applications of Polyglykol 350
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Fields of applications of Polyglykol 350:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste and injection fluids)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metal working fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives
- Heat transfer medium

Product data of Polyglykol 350:
water content (DIN 51777) % m/m max. 0.5
pH (5 % w/w in water) (HOE 06 HB 0211) 5 – 7
molecular weight g/mol about 350
solidification point (EP III) °C about 0
viscosity at 20°C (DIN 51562) mm2/s : 85 – 90
flash point (DIN 51376) °C 220
ignition temperature (DIN 51794) °C > 320
ethylene oxide ppm max. 1
dioxane ppm max. 1

Product Function:
Intermediate & process aid

Chemical Type:
Polyethylene glycol

Applications of Polyglykol 350:
Chemical synthesis
Resin synthesis

Benefitsof Polyglykol 350:
Low sodium content, moderately enhances hydrophilicity, improves biocompatibility of silicones and polymers.

SpectraBase Spectrum ID: DyrcGf0M5wc
Name: Polyglykol 350
Boiling Point: 250.0 °C
CAS Registry Number: 27252-80-8
Classification: Polyethylene glycol allyl methyl ether
Comments: Atmospheric correction
Flash Point: 136 °C
Melting Point: -4.0 °C
Molecular Weight: 350.000 g/mol
Sample Description: light yellow liquid
SpectraBase Batch ID: 9qZVUlDYBOy
Technique: ATR-IR

Polyglykol 350 is a polyethylene glycol monomethyl ether.
Polyglykol 350 is a clear neutral liquid at room temperature.

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear Polyglykols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 400
Polyglykol 400
Polyglykol 400 G

Composition of Polyglykol 400:
Polyethylene glycol

H(OCH2CH2)nOH
n = about 9

CAS-No.: 25322-68-3
INCI-designation: PEG-8

Polyglykol 400 is a polyethylene glycol with a mean molecular weight of 400.
Polyglykol 400 is a clear, viscous hygroscopic liquid.

Polyglykol 400 is a clear viscous liquid polyethylene glycol at room temperature.
Polyglykol 400 is soluble in water and polar organic solvents like acetone or methanol.

Polyglykol 400 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.
Polyglykol 400 is suitable for hand dishwashing detergents, wool and fine-fabric washing powders for manual washing, hand and all-purpose wash pastes, hard surface cleaners, all liquid wash and cleaning agents, especially suited for highly concentrated products, viscosity regulators, detergent boosters, solubilizers.

Benefits of Polyglykol 400:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety
-Good biodegradability

PEG-8.
Polyglykol 400 is a non-volatile humectant, solubilizer, moisturizer, antistatic agent and fixative.
Polyglykol 400 offers softening, cleansing and non-irritating properties.
Polyglykol 400 provides low toxicity and hygroscopic effect.

Polyglykol 400 can be used in creams and all preparations that tend to dry out.
Polyglykol 400 also acts as a cleansing agent in face lotions and as non-greasy lubricant and perfume stabilizer in after-shave lotions.
Polyglykol 400 can be used in lipsticks as solubilizers for tetrabromo fluorescein and its derivatives and in hair care products where improves the consistency of non-greasy hair care products which can be washed out with clear water.

Polyglykol 400 counteracts the tendency of these products to dry to a brittle film.
Polyglykol 400 has very low water content, good biodegradability and is compatible with hard water.
Polyglykol 400 is also used in hair styling products as a plasticizer and anti-static agent.

Polyglykol 400 is also applicable in toothpaste where it improves consistency and storage stability.
Polyglykol 400 has a shelf life of 2 years.

Polyglykol 400 is a Polyethylene glycol with a mean molecular weight of 400.
Polyglykol 400 is a clear, viscous hygroscopic liquid.

INCI Name: PEG-8
Function: Solubilizer, Filler, Plasticizer, Moisturizing Agent, Anti-Static Agent, Binder, Humectant, Cleansing Agent
CAS Number: 25322-68-3
Chemical Family: Polyols, Polyglykols, Polyethylene Glycols
Dosage Form: Creams, Ointments, Capsules

Product properties of Polyglykol 400:
Polyglykol 400 and Polyglykol 400 G are clear viscous liquid at room temperature.
Polyglykol 400 / 400 G can be supplied in tank trucks or in steel drums.
Polyglykol 400's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 400.

Therefore Polyglykol 400 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 400 is insoluble in pure hydrocarbons.
Polyglykol 400 displays typical chemical reactions of alcohols/diols.

In comparision to the standard Polyglykol 400 the alkali ion residue of Polyglykol 400 G is minimized.
Therefore Polyglykol 400 G can be used for polyurethane synthesis.
The solidification point, of Polyglykol 400 is about 6°C.

Product Functions of Polyglykol 400:
-Moisturizer
-Solublizers
-Binders
-Humectant

Polyglykol 400 acts as a release agent.
Polyglykol 400 is clear, viscous, non-volatile and hygroscopic polyethylene glycol liquid at room temperature.
Polyglykol 400 is APEO-free and has low water & VOC content.

Polyglykol 400 exhibits very low water content, good biodegradability and outstanding toxicological safety.
Polyglykol 400 shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 400 is compatible with hard water, cellulose, polyester, rubber, elastomer and polyurethane.

Polyglykol 400 is used for rubber and elastomer processing.
Polyglykol 400 is Ecolabel and FDA (21 CFR 177.2800 and 181.30) compliant.
Polyglykol 400 has a shelf life of 2 years.

Polyglykol 400 is a non-volatile humectant, solubilizer, moisturizer, antistatic agent and fixative.
Polyglykol 400 offers softening, cleansing and non-irritating properties.
Polyglykol 400 provides low toxicity and hygroscopic effect.
Polyglykol 400 can be used in creams and all preparations that tend to dry out.
Polyglykol 400 also acts as a cleansing agent in face lotions and as non-greasy lubricant and perfume stabilizer in after-shave lotions.
Polyglykol 400 can be used in lipsticks as solubilizers for tetrabromo fluorescein and its derivatives and in hair care products where improves the consistency of non-greasy hair care products which can be washed out with clear water.

Polyglykol 400 counteracts the tendency of these products to dry to a brittle film.
Polyglykol 400 has very low water content, good biodegradability and is compatible with hard water.
Polyglykol 400 is also used in hair styling products as a plasticizer and anti-static agent.
Polyglykol 400 is also applicable in toothpaste where it improves consistency and storage stability.

Storage of Polyglykol 400:
When Polyglykol 400 is stored in a cold, dry place in a closed container Polyglykol 400 or 400 G can be kept for at least two years.

Applications of Polyglykol 400:
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Fields of applications of Polyglykol 400:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste and injection fluids)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metal working fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives
- Heat transfer medium

Product data of Polyglykol 400:
water content (DIN 51777) % m/m max. 0.5
colour index [APHA] (EN 1557) (25 % in water) max. 15
pH (10% w/w in water) (DIN EN 1262):
5 – 7
4 – 7 (400 G)
hydroxyl number (HOE 06 HB 0211) mg KOH/g 267 – 295
molecular weight g/mol 380 – 420
solidification point (EP III) °C 4 – 8
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas 110 – 124
flash point (DIN 51376) °C 240
ignition temperature (DIN 51794) °C > 320
ethyleneoxid ppm max. 1
dioxane ppm max. 1

INGREDIENT IDENTIFICATION of Polyglykol 400:
Name:
Polyglykol 400

Segment:
Personal care

INCI name:
PEG-8

CAS numbers:
25322-68-3

GENERAL USES of Polyglykol 400:
Performance claims, Sustainability claims, Function, Applications, Usage level

TECHNICAL USES of Polyglykol 400:
Chemical group, Chemical properties, Physical properties, Appearance, Colors, Origin, Origin Species

SAFETY AND CERTIFICATIONS of Polyglykol 400:
GHS classification, Hazard statements, Certifications, Renewable Carbon Index (RCI)

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear Polyglykols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 400
PEG-90 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (90 mol EO average molar ratio) CAS Number 25322-68-3
POLYGLYKOL 4000 FL
INCI Name: PEG-90
Chemical Name: PEG 4000
Function: Solubilizer, Humectant, Thickener, Viscosity Modifier, Slip Agent, Plasticizer, Carrier, Solvent, Binder, Anti-Static Agent, Lubricant
CAS Number: 25322-68-3
Ingredient Origin: Synthetic

Polyglykol 4000 FL is a yellowish wax-like solid at room temperature.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.

Polyglykol 4000 is insoluble in pure hydrocarbons.
Polyglykol 4000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.

Composition of Polyglykol 4000 FL:
Polyethylene glycol with 90 mol EO

Polyglykol 4000 FL is a polyethylene glycol that is used for a wide variety of applications including: reactive diol/polyether component in polyester or polyurethene resins; component of auxiliaries for leather and textile processing; cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste); lubricant and mould release agent for rubber, plastic and elastomer processing; plasticizer and binder for ceramic and concrete manufacturing; component of lubricant formulations; water soluble, lubricating component in metalworking fluids; humectant for paper, wood and cellulose films; solvent and humectant for dyes and inks; modifier for production of regenerated viscose; and humectant and plasticizer for adhesives.
Polyglykol 4000 FL can be supplied in heated tank trucks, and it has a molecular weight of 3700 – 4400g/mol.

Polyglykol 4000 FL is a white waxy solid polyethylene glycol at room temperature.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.

PEG-90.
Polyglykol 4000 FL is a slip, solubilizer, carrier, thickener and antistatic agent.
Polyglykol 4000 FL offers softening, binding & non-irritating properties, low toxicity and no emulsifying effect.

Polyglykol 4000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is used in skin-care products.

Product properties of Polyglykol 4000 FL:
Concentration [%]:
approx. 100

Relative molar mass [Dalton]:
3700 - 4400

Appearance:
wax

Delivery form:
melt

Hazen colour, 25% in water:
max. 30

Solidification point [°C]:
53 - 58

Hydroxyl number [mg KOH/g]:
25 - 30

Viscosity, 20°C, 50% in water [mPas]:
114 - 142

Water (Karl Fischer method) [%]:
max. 0.1

pH value, 5% in water:
5.0 – 7.0

Oxide ash [%]:
max. 0.05

Solubility in water:
dissolves to a clear solution

Applications of Polyglykol 4000 FL:
Washing powders and tabs, dissolving aids, tabletting and granulation auxiliaries, binding agents, toilet blocks.

Storage of Polyglykol 4000 FL:
Polyglykol 4000 FL can be stored for at least to 2 years in original sealed containers at room temperature under the recommended conditions.
Polyglykol 4000 FL undergoes no change whatever in It's product properties when exposed to cold during transport and storage.

Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 4000 FL acts as a solvent, humectant and plasticizer.

Polyglykol 4000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.

Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 4000 FL is suitable for use in cellulose films and paints.

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear Polyglykols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 4000 P
PEG-90,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (90 mol EO average molar ratio) CAS:25322-68-3
Polyglykol 4000 PF
PEG-90, Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (90 mol EO average molar ratio) CAS:25322-68-3
Polyglykol 4000 PS
PEG-75 Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (75 mol EO average molar ratio) CAS Number 25322-68-3
Polyglykol 4000 S
PEG-8 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (8 mol EO average molar ratio) CAS Number 5117-19-1 / 25322-68-3 (generic)
POLYGLYKOL 4000 S PHARMA
PEG-12 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (12 mol EO average molar ratio) CAS Number 25322-68-3
POLYGLYKOL 5500
Polyglykol 5500 FL

Composition: Polyethylene glycol
H(OCH2CH2)nOH
n = about 125

CAS-No.: 25322-68-3

Product properties of Polyglykol 5500:
Polyglykol 5500 is a white waxy solid at room temperature.
Polyglykol 5500 FL melt can be supplied in heated tank trucks.
Polyglykol 5500's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 5500.

Therefore Polyglykol 5500 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 5500 is insoluble in pure hydrocarbons.

Polyglykol 5500 displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 5500 is about 58°C.

Storage of Polyglykol 5500:
In solidified form Polyglykol 5500 fl can be kept for at least two years.
As melt Polyglykol 5500 fl has to be kept at temperatures of 60 – 80°C under nitrogen atmosphere.
At these temperatures storage time of Polyglykol 5500 has to be limited to maximum 6 month.

Applications of Polyglykol 5500:
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Product Function:
Intermediate & process aid

Chemical Type:
Polyethylene glycol

Applications of Polyglykol 5500:
Paint additive manufacturing
Chemical synthesis

Fields of applications of Polyglykol 5500:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or plasticiser for creams, tablets, tooth paste)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metalworking fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives

Polyglykol 5500 FL is a polyethylene glycol that is used for a wide variety of applications including: reactive diol/polyether component in polyester or polyurethene resins; component of auxiliaries for leather and textile processing; cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste); lubricant and mould release agent for rubber, plastic and elastomer processing; plasticizer and binder for ceramic and concrete manufacturing; component of lubricant formulations; water soluble, lubricating component in metalworking fluids; humectant for paper, wood and cellulose films; solvent and humectant for dyes and inks; modifier for production of regenerated viscose; and humectant and plasticizer for adhesives.
Polyglykol 5500 has a molecular weight of 5100 – 5900g/mol.
Polyglykol 5500 FL melt can be supplied in heated tank trucks.

Polyglykol 5500's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 5500.
Therefore Polyglykol 5500 is soluble in water and polar organic solvents like aceton or methanol.

Polyglykol M 5000 FL is a monomethoxy polyethylene glycol with a molecular weight of 4500 – 5500g/mol.
Polyglykol 5500 is a waxy white to slightly yellowish solid at room temperature with only very light smell.
Polyglykol 5500 is supplied in a heated tank truck.

M-type polyglycols are used for a wide variety of chemical reactions.
With isocyanates and polyester they act as endcapping and hydrophilic component.
When reacted with unsaturated monomers like acrylic or methacrylic acid esters are formed which can be copolymerisized in order to increase hydrophilicity and improve dispersing properties of polymers in water.

Product data:
water content (DIN 51777) % m/m max. 0.1
colour index [APHA] (EN 1557) (25 % in water) max. 30
pH (5 % w/w in water) (DIN EN 1262) 5 – 7
hydroxyl number (DIN 53240) mg KOH/g 19 – 22
molecular weight g/mol 5100 – 5900
solidification point (EP III) °C 55 – 60
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas 167 - 219
flash point (DIN 51376) °C 255
ignition temperature (DIN 51794) °C >320
ethylene oxide ppm max. 1
dioxane ppm max. 1

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear polyglycols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 600
Polyglykol 600
Polyglykol 600 A
Polyglykol 600 PU
Polyglykol 600 M 60

Composition: Polyethylene glycol
H(OCH2CH2)nOH
n = about 13

CAS-No.: 25322-68-3
INCI-designation: PEG-12

Polyglykol 600 is a clear viscous liquid polyethylene glycol.
Polyglykol 600 is soluble in water and polar organic solvents.

Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.
Polyglykol 600 is recommended for highly concentrated products, viscosity regulators, detergent boosters, solubilizers and oral care applications.

Polyglykol 600 is a clear viscous liquid polyethylene glycol.
Polyglykol 600 is soluble in water and polar organic solvents.

Polyglykol 600 is insoluble in pure hydrocarbons and displays typical chemical reactions of alcohols/diols.
Polyglykol 600 is recommended for hand dishwashing detergents, wool and fine-fabric washing powders for manual washing, hand and all-purpose wash pastes, hard surface cleaners, all liquid wash and cleaning agents, especially suited for highly concentrated products, viscosity regulators, detergent boosters, solubilizers.

Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Benefits of Polyglykol 600:
-Good solubility in water
-Very low water content
-Compatible with hard water
-Non-volatile
-Outstanding toxicological safety
-Good biodegradability

Chemical Name:
PEG-12

Product Function:
Humectant

Chemical Type:
Polyethylene glycol

Applications of Polyglykol 600:
-Shower, Liquid Soap
-Shampoo
-Syndet, Bar Soap
-Hair Styling
-Cream, Lotion
-Antiperspirant & Deodorant
-Performance Claims
-Water-soluble
-Moisturizing
-Anti-perspirant
-Conditioning

Product properties of Polyglykol 600:
Polyglykol 600 is clear viscous liquid at room temperature.
Polyglykol 600 can be supplied in tank trucks or in steel drums.

Polyglykol 600s two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 600.
Therefore Polyglykol 600 is soluble in water and polar organic solvents like aceton or methanol.

Polyglykol 600 is insoluble in pure hydrocarbons.
Polyglykol 600 displays typical chemical reactions of alcohols/diols.

The solidification point, of Polyglykol 600 is about 20°C.
Besides standard grade Polyglykol 600 special qualities Polyglykol 600 PU and Polyglykol 600 A with low sodium concentrations and/or low water concentrations are available on request.

Storage of Polyglykol 600:
When Polyglykol 600 is stored in a cold, dry place in a closed container Polyglykol 600 can be kept for at least two years.

Applications of Polyglykol 600:
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Fields of applications of Polyglykol 600:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste and injection fluids)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metal working fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives
- Heat transfer medium

Product Type:
Solvents > Glycols & Glycol Ethers > Ethylene Glycols
Plasticizers
Humectants

Chemical Composition: Polyethylene glycol
CAS Number: 25322-68-3
Physical Form: Wax
Appearance : Colorless
Product Status: COMMERCIAL
Applications/ Recommended for: Coatings

Product data:
water content (DIN 51777) % m/m
max. 0.5
max. 0.1 (for 600 PU and 600 A)
39 – 41 (for 600 M 60)
colour index [APHA] (EN 1557) (25 % in water): max. 15
pH (5 % w/w in water) (DIN EN 1262):
5 – 7
5 – 7.2 (for 600 A)
3 – 5 (for 600 PU)
hydroxyl number (HOE 06 HB 0211) mg KOH/g: 178 – 197
molecular weight g/mol: 570 – 630
solidification point (EP III) °C: 17 – 22
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas: 16 – 19
flash point (DIN 51376) °C: 265
ignition temperature (DIN 51794) °C >: 320
ethylene oxide ppm max.: 1
dioxane ppm max.: 1

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear Polyglykols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 600
PEG-150 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (150 mol EO average molar ratio) CAS: 25322-68-3
POLYGLYKOL 6000 P PHARMA
PEG-150,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (150 mol EO average molar ratio) CAS Number 25322-68-3
POLYGLYKOL 6000 PF
PEG-150 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (150 mol EO average molar ratio) CAS: 25322-68-3
Polyglykol 6000 PS
For use as solvent or humectant Polyethyleneglykol ; cas no: 25322-68-3; Flakes ; 100%
POLYGLYKOL 6000 S PHARMA
PEG-180,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (180 mol EO average molar ratio) CAS Number 25322-68-3
POLYGLYKOL 800
INCI Name: PEG-16
Chemical Name: PEG 800
Function: Solubilizer, Humectant, Moisturizing Agent, Solvent, Anti-Static Agent
CAS Number: 25322-68-3
Ingredient Origin: Synthetic

Polyglykol 800 is a polyethylene glycol that is used for a wide variety of applications as a humectant, solubilizer, lubricant, plasticizer, and modifier.
Polyglykol 800 is a white waxy solid at room temperature.
Polyglykol 800 can be supplied in heated tank trucks or in steel drums.

Polyglykol 800's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 800.
Therefore, Polyglykol 800 is soluble in water and polar organic solvents like aceton or methanol.

PEG-16.
Polyglykol 800 is a humectant, solubilizer, antistatic agent and fixative.
Polyglykol 800 possesses non-irritating, softening and cleansing properties.

Polyglykol 800 offers low toxicity and no emulsifying effect.
Polyglykol 800 is used in tooth-pastes and perfumes.

Product Function of Polyglykol 800:
-Intermediate & process aid

Chemical Type:
-Polyethylene glycol

Applications of Polyglykol 800:
-Chemical synthesis
-Process aid

Advantages of Polyglykol 800:
-Posesses softening, non irritating and cleansing properties
-Offers low toxicity
-no emulsifying effect

Polyglykol 800 Features & Benefits:
Benefit Claims:
-Anti-Irritant
-Film Forming
-Humectancy
-Solubilizing
-Static Reduction

Composition:
-Polyethylene glycol

H(OCH2CH2)nOH
n = about 18

CAS-No.: 25322-68-3
INCI- designation: PEG-16

Product properties of Polyglykol 800:
Polyglykol 800 is a white waxy solid at room temperature.
Polyglykol 800 can be supplied in heated tank trucks or in steel drums.
Polyglykol 800's two hydroxy end groups as well as its ether groups mainly control the physical and chemical properties of Polyglykol 800.

Therefore Polyglykol 800 is soluble in water and polar organic solvents like aceton or methanol.
Polyglykol 800 is insoluble in pure hydrocarbons.
Polyglykol 800 displays typical chemical reactions of alcohols/diols.
The solidification point, of Polyglykol 800 is about 28 °C.

Storage of Polyglykol 800:
When Polyglykol 800 is stored in a cold, dry place in a closed container Polyglykol 800 can be kept for at least two years.

Applications of Polyglykol 800:
Based on their physical and chemical characteristics - polyethylene glycols are used for a wide variety of applications.

Fields of industrial applications of Polyglykol 800:
- Reactive diol/polyether component in polyester or polyurethene resins
- Component of auxiliaries for leather and textile processing
- Cosmetic / pharmaceutical formulations (e.g. humectant or solubilizer for creams, shampoos, tooth paste)
- Lubricant and mould release agent for rubber and elastomer processing
- Plasticizer and binder for ceramic and concrete manufacturing
- Component of lubricant formulations
- Water soluble, lubricating component in metalworking fluids
- Humectant for paper, wood and cellulose films
- Solvent and humectant for dyes and inks
- Modifier for production of regenerated viscose
- Humectant and plasticizer for adhesives
- Heat transfer medium

Identification & Functionality of Polyglykol 800:
Chemical Family:
-Polyethylene Glycols, Polyols

Applications & Uses of Polyglykol 800:
-Markets: Personal Care

Applications of Polyglykol 800:
Personal Care — Beauty & Care:
-AP/Deo
-Bath & Shower
-Hair Care
-Oral Care
-Skin Care

Personal Care — Personal Hygiene:
-Hand Hygiene

Application Format of Polyglykol 800:
-Bar
-Creams
-Gel
-Lotions
-Rinse Off
-Roll On
-Serum
-Spray

AP/Deo Applications of Polyglykol 800:
-Antiperspirants & Deodorants

Bath & Shower Applications of Polyglykol 800:
-Bar Soaps
-Body Wash & Cleanser
-Bubble Bath

Fragrances & Perfume Applications of Polyglykol 800:
-Fragrances & Perfumes

Hair Care Applications of Polyglykol 800:
-Hair Styling Products
-Shampoos & Rinses

Oral Care Applications of Polyglykol 800:
-Toothpaste

Personal Hygiene Applications of Polyglykol 800:
-Hand Soap
-Liquid Hand Soap

Skin Care Applications of Polyglykol 800:
-Body Balms, Creams & Lotions
-Face Creams & Lotions
-Hand Cream

Chemical Name: PEG 800

INCI Name: PEG-16

Ingredient Origin: Synthetic

Cleaning Ingredients Functions: Solvent

Cosmetic Ingredients Functions of Polyglykol 800:
-Anti-Static Agent
-Humectant
-Moisturizing Agent
-Solubilizer
-Solvent

CAS No.: 25322-68-3

Product data:
water content (DIN 51777) % m/m max. 0.5
colour index [APHA] (EN 1557) (25 % in water) max. 15
pH (5 % w/w in water) (DIN EN 1262) 5 – 7
hydroxyl number (HOE 06 HB 0211) mg KOH/g 134 – 148
molecular weight g/mol 760 – 840
solidification point (EP III) °C 25 – 30
viscosity at 20°C (50 % w/w in water) (DIN 51562) mPas 21 – 23
flash point (DIN 51376) °C 270
ignition temperature (DIN 51794) °C >320
ethylene oxide ppm max. 1
dioxane ppm max. 1

Technologies:
-Cleaning Ingredients
-Cosmetic Ingredients

Product Families:
-Cleaning Ingredients — Functional Additives: Solvents & Carriers
-Cosmetic Ingredients — Functionals: Emulsifiers, Solubilizers & Dispersants, Solvents & Carriers

Other products:
Polyglykol 1000
Polyglykol 1000 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1000 is suitable for paint additive manufacturing.

Polyglykol 1000 SG VITA
Polyglykol 1000 SG VITA t is a polyethylene glycol-based solvent.
Polyglykol 1000 SG VITA is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 1000 SG VITA is recommended for paint additive manufacturing.

Polyglykol 10000 S
Polyglykol 10000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 10000 S is suitable for paints and coatings.
The shelf life of Polyglykol 10000 S is 6 months.

Polyglykol 10000 SG
Polyglykol 10000 SG Vita is polyethylene glycol-based solvent.
Polyglykol 10000 SG is 100% bio-based with a fully segregated supply chain and a renewable carbon index (RCI) of 100%.
Polyglykol 10000 SG Vita is recommended for paint additive manufacturing.

Polyglykol 12000 S
Polyglykol 12000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 12000 S is suitable for paint additive manufacturing.

Polyglykol 1500 FL PU
Polyglykol 1500 FL PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 1500 FL PU is suitable for paints and coatings.

Polyglykol 1500 S
Polyglykol 1500 S is a polyethylene glycol-based carrier, solvent, humectant and plasticizer with good biodegradability.
Polyglykol 1500 S possesses very low water content and good solubility in water.
Polyglykol 1500 S is suitable for paints and coatings.

Polyglykol 2000 PU
Polyglykol 2000 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 PU is used in paints and coatings.

Polyglykol 2000 S
Polyglykol 2000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 2000 S possesses low melting range, very low water content and excellent solubility in water.
Polyglykol 2000 S is suitable for paints and coatings.

Polyglykol 300
Polyglykol 300 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 300 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 300 prevents the formation of skin or lumps on the surface of the dispersion.
Polyglykol 300 is used in water-based and solvent-borne alkyd end-use pigment preparations.
The recommended dosage for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 400
Polyglykol 400 is an APEO-free, polyethylene glycol-based humectant.
Polyglykol 400 is used in water-based and solvent-borne alkyd end-use pigment preparations.
Polyglykol 400 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 400 prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage of Polyglykol 400 for point-of-sales colorants and in-plant titters is 4-8% and 6-10% respectively.

Polyglykol 4000 S
Polyglykol 4000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 4000 S possesses very low water content and excellent solubility in water.
Polyglykol 4000 S is used in paints and coatings.

Polyglykol 600
Polyglykol 600 is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 is used in paints and coatings.

Polyglykol 600 PU
Polyglykol 600 PU is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 600 PU is suitable for paints and coatings.

Polyglykol 6000 P
Polyglykol 6000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 6000 P possesses very low water content and excellent solubility in water.
Polyglykol 6000 P is suitable for paints and coatings.

Polyglykol 6000 S
Polyglykol 6000 S is a polyethylene glycol grade-based solvent, humectant and plasticizer.
Polyglykol 6000 S shows very low water content and good solubility in water.
Polyglykol 6000 S is suitable for paints and coatings.

Polyglykol 8000 P
Polyglykol 8000 P is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 P possesses very low water content and good solubility in water.
Polyglykol 8000 P is suitable for paints and coatings.

Polyglykol 8000 S
Polyglykol 8000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 8000 S shows very low water content and good solubility in water.
Polyglykol 8000 S is suitable for paints and coatings.

Polyglykol 9000 S
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant and plasticizer.
Polyglykol 9000 S is suitable for paint additive manufacturing.
The shelf life of Polyglykol 9000 S is 2 years.

Polyglykol AB/25-8
Polyglykol AB/25-8 is a poly alkyl ethylene glycol, butyl ether.
Polyglykol AB/25-8 displays moderate enhancement of hydrophilicity.
Polyglykol AB/25-8 also enhances material- and biocompatibility of polymers.
Polyglykol AB/25-8 is suitable for paint additive manufacturing.

Polyglykol AM 1100
Polyglykol AM 1100 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 1100 enhances hydrophilicity with increasing chain length.
Polyglykol AM 1100 also enhances material- and biocompatibility of polymers.
Polyglykol AM 1100 is suitable for paint additive manufacturing.

Polyglykol AM 250
Polyglykol AM 250 is a polyethylene glycol allyl methyl ether.
Polyglykol AM 250 enhances hydrophilicity with increasing chain length.
Polyglykol AM 250 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 250 is suitable for paint additive manufacturing.

Polyglykol AM 450
Polyglykol AM 450 is a polyethylene glycol allyl methyl ether with low sodium content.
Polyglykol AM 450 enhances hydrophilicity with increasing chain length.
Polyglykol AM 450 also enhances material- and biocompatibility of silicones & polymers.
Polyglykol AM 450 is used in paints and coatings.

Polyglykol D 21/150
Polyglykol D 21/150 is a solvent and humectant.
Polyglykol D 21/150 is suitable for paints and coatings.

Polyglykol D 21/300
Polyglykol D 21/300 is a solvent and humectant.
Polyglykol D 21/300 is used in paints and coatings.

Polyglykol D 21/700
Polyglykol D 21/700 is a solvent and humectant.
Polyglykol D 21/700 is suitable for paints and coatings.

Polyglykol G 500
Polyglykol G 500 is a preservative-free, humectant designed for waterborne pigment preparations.
Polyglykol G 500 offers lower preparation viscosities compared with conventional linear polyglycols, low VOC-content and little impact on wet scrub resistance at usual charges.
Polyglykol G 500 retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
This APEO-free product prevents the formation of skin or lumps on the surface of the dispersion.
The recommended dosage for pigment preparations varies from 5-15% on the preparation.
The shelf life of Polyglykol G 500 is 730 days.
Polyglykol G 500 is compliant with ecolabel criteria.

Polyglykol M 1000
Polyglykol M 1000 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 1000 is suitable for paints and coatings.
The shelf life of this product is 2 years.

Polyglykol M 2000 FL
Polyglykol M 2000 FL is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 FL is used in paints and coatings.

Polyglykol M 2000 S
Polyglykol M 2000 S is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 2000 S is used in paints and coatings.

Polyglykol M 350
Polyglykol M 350 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether with low water content.
Polyglykol M 350 contains low content of diol contaminants.
Polyglykol M 350 possesses narrow molecular weight distribution.
Polyglykol M 350 is used in paints and coatings.

Polyglykol M 350 PU
Polyglykol M 350 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 350 PU possesses low content of diol contaminants.
Polyglykol M 350 PU is used in paints and coatings.

Polyglykol M 500
Polyglykol M 500 is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 PU
Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 500 PU offers low alkali and low water content.
Polyglykol M 500 PU is suitable for paints and coatings.

Polyglykol M 750
Polyglykol M 750 is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether.
Polyglykol M 750 is used in paints and coatings.
The shelf life of Polyglykol M 750 is 2 years.

Polyglykol M 750 PU
Polyglykol M 750 PU is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 750 PU is suitable for paints and coatings.

Polyglykol 10000 FL
Polyglykol 10000 FL is a polyethylene glycol.
Polyglykol 10000 FL acts as a humectant, solvent, and plasticizer.
Polyglykol 10000 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 10000 FL is a yellowish liquid.
Polyglykol 10000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 10000 FL is insoluble in pure hydrocarbons.
Polyglykol 10000 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 10000 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 FL
Polyglykol 1500 FL is a polyethylene glycol grade.
Polyglykol 1500 FL acts as a plasticizer, solvent and humectant.
Polyglykol 1500 FL shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 FL is a yellowish liquid.
Polyglykol 1500 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 FL is insoluble in pure hydrocarbons.
Polyglykol 1500 FL is compatible with cellulose, polyester and polyurethane.
Polyglykol 1500 FL is suitable for use in cellulose films and paints.

Polyglykol 1500 PS
Polyglykol 1500 PS is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer. Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 1500 PS is a yellow powder.
Polyglykol 1500 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 1500 PS is insoluble in pure hydrocarbons.
Polyglykol 1500 PS is compatible with cellulose, polyester and polyurethane.

Polyglykol 200 LVC
Polyglykol 200 LVC is a polyethylene glycol with a weight average molecular weight of 200 g/mole.
Acts as a solvent and humectant.
Polyglykol 200 LVC is APEO-free and has low VOC content.
Polyglykol 200 LVC retards the drying of pigment pastes and forms a soluble film of the pigment preparation.
Polyglykol 200 LVCs recommended dosage in pigment preparations is 5 – 15%, for organic pigments is 25-30% on pigments and for inorganic pigments is 10-15% on pigments.
Polyglykol 200 LVC is Ecolabel compliant.
Polyglykol 200 LVC is listed on REACH, AICS, DSL, ENCS, IECSC, KECI, NECI, NZIoC, PICCS and TSCA inventories.

Polyethylene glycol
Polyethylene glycol slows down the drying of pigment preparations and prevent skin formation.
Ideal dosage on organic pigment is 10-12%.
Polyethylene glycol is used as humectants, retention agent and solvent in waterborne pigments.
Polyethylene glycol is approved for ecolabels and complies with the following regulations: environmental label (blue angel), EINECS, TSCA, DSL, AICS, CN, ECL, and METI.

Polyglykol 2000 FL
Polyglykol 2000 FL is a polyethylene glycol grade suitable for use in cellulose films and paints.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 2000 FL is available as a yellow liquid.
Polyglykol 2000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 2000 FL is insoluble in pure hydrocarbons.
Polyglykol 2000 FL is compatible with cellulose, polyester and polyurethane.

Polyglykol 3400 FL
Polyglykol 3400 FL is a polyethylene glycol grade soluble in water & polar organic solvents like acetone or methanol.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 3400 FL is available as yellow liquid.
Polyglykol 3400 FL is insoluble in pure hydrocarbons.
Polyglykol 3400 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 3400 PS
Polyglykol 3400 PS is a polyethylene glycol grade available as yellow powder.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Acts as a solvent, humectant and plasticizer.
Polyglykol 3400 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 3400 PS is insoluble in pure hydrocarbons.
Polyglykol 3400 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PS
Polyglykol 4000 PS is a polyethylene glycol grade available as spray dried powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PS is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PS is insoluble in pure hydrocarbons.
Polyglykol 4000 PS is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 FL
Polyglykol 4000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 FL is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 FL is insoluble in pure hydrocarbons.
Polyglykol 4000 FL is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 M50
Polyglykol 4000 M50 is a white waxy solid polyethylene glycol supplied at 50% solution in water at room temperature.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 M50 is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 M50 is insoluble in pure hydrocarbons.
Polyglykol 4000 M50 is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 P
Polyglykol 4000 P is a polyethylene glycol grade available as yellow powder.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 P is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 P is insoluble in pure hydrocarbons.
Polyglykol 4000 P is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PF
Polyglykol 4000 PF is a polyethylene glycol grade available as solid in fine powder form.
Acts as a solvent, humectant and plasticizer.
Shows typical chemical reactions of alcohols/diols and a very low evaporation rate.
Polyglykol 4000 PF is soluble in water and polar organic solvents like acetone or methanol.
Polyglykol 4000 PF is insoluble in pure hydrocarbons.
Polyglykol 4000 PF is compatible with cellulose, polyester and polyurethane.
Suitable for use in cellulose films and paints.

Polyglykol 4000 PSK
Polyglykol 4000 PSK is a polyethylene glycol grade acting as a humectant, plasticizer and solvent.

Polyglykol 6000 FL
Polyglykol 6000 FL is a polyethylene glycol grade available as yellowish liquid.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PF
Polyglykol 6000 PF is a yellow colored polyethylene glycol grade present as fine powder form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 6000 PS
Polyglykol 6000 PS is a polyethylene glycol grade available as yellow spray dried powder.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 FL
Polyglykol 8000 FL is a yellow colored polyethylene glycol grade available in liquid form.
Acts as a solvent, humectant and plasticizer.

Polyglykol 8000 PF
Polyglykol 8000 PF is a polethylene glycol grade with a mean molecular weight of 8000.
Polyglykol 8000 PF is a yellowish wax-like solid at room temperature.

Polyglykol 8000 PS
Polyglykol 8000 PS is a polethylene glycol available as yellowish wax-like solid at room temperature.
Polyglykol 8000 PS has a mean molecular weight of 8000.

Polyglykol 9000 FL
Polyglykol 9000 FL is a polyethylene glycol grade available as yellowish liquid.
Polyglykol 9000 FL acts as a solvent, humectant and plasticizer.

Polyglykol A 11/1800
Polyglykol A 11/1800 is a hygroscopic polyalkylene glycol monoallyl ether.

Polyglykol A 32/550
Polyglykol A 32/550 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 32/550 is a clear, yellowish liquid at room temperature.

Polyglykol A 400
Polyglykol A 400 is a hygroscopic polyalkylene glycol monoallyl ether grade.
Polyglykol A 400 is neutral and soluble in water & commonly used organic solvents like acetone or methanol.

Polyglykol A 500
Polyglykol A 500 is a polyethylene glycol monoallyl ether.
Polyglykol A 500 is a clear, yellowish liquid at room temperature.

Polyglykol PR 600
Polyglykol PR 600 is a polyalkylenglycol available as clear liquid.
Acts as a solvent and humectant.
Shows typical chemical reactions of alcohols/diols.
POLYGLYKOL 8000 P
PEG-180 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (180 mol EO average molar ratio) CAS Number 25322-68-3
POLYGLYKOL 8000 PF
PEG-180 ,Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, (180 mol EO average molar ratio) CAS Number 25322-68-3
POLYGLYKOL 8000 S
PAPE; PAE; Polyol phosphate ester; Polyhydric alcohol phosphate ester CAS NO:8619-19-2
POLYGLYKOL 9000 S

Polyglykol 9000 S is designed for use in paint additive manufacturing and is available in a solid flake form.
Polyglykol 9000 S has a mean molecular weight of 9000.
Polyethylene glycols (PEGs) are a family of polymers that are produced by polymerizing ethylene oxide.
They are often used in various applications due to their solubility in water and many organic solvents, as well as their ability to enhance the performance of formulations.

CAS Number: 25322-68-3



APPLICATIONS


Polyglykol 9000 S is used in paint manufacturing to enhance stability, texture, and performance.
Polyglykol 9000 S is applied in architectural coatings to improve flexibility and durability.

Polyglykol 9000 S is utilized as a plasticizer in adhesive formulations to enhance flexibility.
Polyglykol 9000 S finds application in the production of printing inks to achieve desired viscosity and flow properties.
Polyglykol 9000 S is used in textile printing as a solvent and dye carrier to improve color intensity.

Polyglykol 9000 S can be found in cosmetic formulations as a solubilizer and humectant.
Polyglykol 9000 S is used in personal care products such as soaps and shampoos to improve moisture retention.
Polyglykol 9000 S is incorporated into pharmaceutical formulations as a solvent or excipient.

Polyglykol 9000 S can be utilized in metalworking fluids to reduce friction and improve lubrication.
Polyglykol 9000 S is applied in industrial cleaning products as a solvent and wetting agent.
Polyglykol 9000 S is used in the leather industry as a plasticizer to enhance flexibility and water resistance.

Polyglykol 9000 S is employed in the production of adhesive tapes to improve adhesive properties.
Polyglykol 9000 S finds application in paper and packaging as a humectant and plasticizer.
Polyglykol 9000 S is utilized in rubber and plastics to enhance elasticity and workability.

Polyglykol 9000 S is used as a dispersing agent and stabilizer in emulsion polymerization.
Polyglykol 9000 S finds application in the construction industry for the formulation of mortars and sealants.
Polyglykol 9000 S is used in metalworking processes to reduce friction and heat generation.

Polyglykol 9000 S is applied in textile and fiber processing as a lubricant and antistatic agent.
Polyglykol 9000 S finds application in soil stabilization to improve moisture retention and compaction properties.

Polyglykol 9000 S is used in the production of industrial coatings for improved flexibility and durability.
Polyglykol 9000 S is employed in the formulation of grouts to enhance workability and adhesion.
Polyglykol 9000 S can be found in cleaning solutions to aid in the removal of dirt and contaminants.

Polyglykol 9000 S is used in the production of adhesives for improved flexibility and moisture retention.
Polyglykol 9000 S finds application in the formulation of sealants for enhanced flexibility and durability.
Polyglykol 9000 S is utilized in the production of rubber products for improved elasticity and workability.



Polyglykol 9000 S has various applications, primarily in the paint and coating industry.
Here are some common applications of Polyglykol 9000 S:

Paint Manufacturing:
Polyglykol 9000 S is used as a solvent, humectant, and plasticizer in the production of paints.
Polyglykol 9000 S enhances the stability, texture, and performance of paint formulations.

Coating Formulations:
Polyglykol 9000 S is employed in the formulation of different types of coatings, including architectural coatings, industrial coatings, and protective coatings.
Polyglykol 9000 S improves the flexibility, durability, and overall quality of the coatings.

Additive Manufacturing:
Polyglykol 9000 S can be used as an additive in the manufacturing of paints.
Polyglykol 9000 S helps in achieving the desired properties, such as improved flow, leveling, and adhesion.

Adhesives:
Polyglykol 9000 S is utilized as a plasticizer and humectant in adhesive formulations, improving their flexibility and moisture retention properties.

Printing Inks:
Polyglykol 9000 S finds application in the production of printing inks, acting as a solvent and plasticizer.
Polyglykol 9000 S aids in achieving the desired viscosity, flow, and adhesion characteristics of the inks.

Textile Printing:
In textile printing, Polyglykol 9000 S can be used as a solvent and dye carrier.
Polyglykol 9000 S helps in dispersing and transferring dyes onto fabrics, improving color intensity and fastness.

Cosmetics:
Due to its solubility in water and many organic solvents, it can be found in certain cosmetic formulations.
Polyglykol 9000 S may be used as a solvent, humectant, or plasticizer in cosmetic products like creams, lotions, and hair care products.

Personal Care Products:
Polyglykol 9000 S can be incorporated into personal care products, such as soaps, shampoos, and shower gels, as a humectant and solubilizer.

Pharmaceuticals:
Polyglykol 9000 S may be used in certain pharmaceutical formulations as a solvent or excipient, assisting in the dispersion and delivery of active ingredients.

Industrial Applications:
Polyglykol 9000 S can have industrial applications as a component in various industrial processes, such as metalworking fluids, lubricants, and cleaners.

Adhesive Tapes:
Polyglykol 9000 S can be incorporated into adhesive tape formulations to improve their adhesive properties and flexibility.

Paper and Packaging:
Polyglykol 9000 S may be used in paper and packaging industries as a humectant and plasticizer to enhance moisture retention and flexibility of paper products, including coatings, adhesives, and sealants.

Leather Processing:
Polyglykol 9000 S can find application in the leather industry as a plasticizer to improve the softness, flexibility, and water resistance of leather products.

Rubber and Plastics:
Polyglykol 9000 S can be utilized as a plasticizer and processing aid in the rubber and plastics industry, enhancing the elasticity, workability, and durability of rubber and plastic products.

Emulsion Polymerization:
Polyglykol 9000 S can serve as a dispersing agent and stabilizer in emulsion polymerization processes, aiding in the formation of stable emulsions and the production of polymer dispersions.

Industrial Cleaning Products:
Polyglykol 9000 S may be incorporated into industrial cleaning formulations as a solvent and wetting agent, assisting in the removal of dirt, oils, and contaminants from surfaces.

Metalworking:
Polyglykol 9000 S can be used as a lubricant and cooling agent in metalworking processes, such as cutting, milling, and grinding, to reduce friction and heat generation.

Textile and Fiber Processing:
Polyglykol 9000 S can find application in textile and fiber processing as a lubricant and antistatic agent, improving the handling and processing of fibers during spinning, weaving, and knitting.

Construction Chemicals:
Polyglykol 9000 S may be employed in the formulation of construction chemicals, such as mortars, grouts, and sealants, to enhance their workability, adhesion, and water retention properties.

Soil Stabilization:
Polyglykol 9000 S can be used in soil stabilization applications, where it aids in improving the moisture retention and compaction properties of soils.



DESCRIPTION


Polyglykol 9000 S is designed for use in paint additive manufacturing and is available in a solid flake form.
Polyglykol 9000 S has a mean molecular weight of 9000.

Polyethylene glycols (PEGs) are a family of polymers that are produced by polymerizing ethylene oxide.
They are often used in various applications due to their solubility in water and many organic solvents, as well as their ability to enhance the performance of formulations.

In the case of Polyglykol 9000 S, its specific properties and characteristics make it suitable for use as a solvent, humectant, and plasticizer in the production of paints.
Polyglykol 9000 S can help improve the stability, texture, and performance of paint formulations.

Additionally, you mentioned that the shelf life of Polyglykol 9000 S is 2 years, which indicates the recommended period for which the product can be stored and used without significant degradation or loss of quality.

Polyglykol 9000 S is a solid flake form of polyethylene glycol with a mean molecular weight of 9000.
Polyglykol 9000 S is a polyethylene glycol-based solvent, humectant, and plasticizer.
Polyglykol 9000 S is primarily used in paint additive manufacturing.

Polyglykol 9000 S is known for its excellent solubility in water and many organic solvents.
Polyglykol 9000 S acts as a versatile and effective solvent for various types of paint formulations.

Polyglykol 9000 S enhances the stability and texture of paint products.

Polyglykol 9000 S serves as a humectant, helping to retain moisture and prevent drying out.
Polyglykol 9000 S also functions as a plasticizer, improving flexibility and durability.
Polyglykol 9000 S contributes to the overall performance and quality of paint coatings.

The mean molecular weight of 9000 ensures a suitable balance of viscosity and flow properties.
Polyglykol 9000 S exhibits excellent compatibility with a wide range of other paint additives.
Polyglykol 9000 S offers good dispersibility, aiding in the uniform distribution of pigments.
Polyglykol 9000 S can enhance the wetting properties of paints, promoting better adhesion.

Polyglykol 9000 S improves the overall workability and application characteristics of paint formulations.
The solid flake form allows for convenient handling and dosing during manufacturing processes.

Polyglykol 9000 S is typically used in combination with other additives to achieve desired performance attributes.
Polyglykol 9000 S is chemically stable and has a relatively long shelf life of 2 years.
Polyglykol 9000 S is produced by polymerizing ethylene oxide, resulting in a high-quality product.

Polyglykol 9000 S meets industry standards for paint manufacturing and formulation requirements.
Polyglykol 9000 S undergoes rigorous quality control measures to ensure consistent performance.

Polyglykol 9000 S is designed to comply with safety and regulatory guidelines for industrial use.
Polyglykol 9000 S is an important component in the development of high-quality, durable paint coatings.

Polyglykol 9000 S offers manufacturers flexibility in formulating custom paint solutions.
Polyglykol 9000 S contributes to the overall aesthetics and longevity of painted surfaces.
The chemical's versatile properties make it a valuable additive for various paint applications.



PROPERTIES


Chemical Name: Polyglykol 9000 S
Chemical Formula: Not applicable (polyethylene glycol-based compound)
CAS Number: 25322-68-3
EC Number: Not available
Mean Molecular Weight: 9000
Physical Form: Solid flakes
Solubility: Highly soluble in water and many organic solvents
Appearance: White to off-white flakes
Odor: Odorless
Shelf Life: Typically 2 years
Density: Varies based on temperature and specific formulation
Melting Point: Varies based on specific formulation
Boiling Point: Varies based on specific formulation
Viscosity: Highly dependent on temperature and concentration
pH: Neutral (around 7)
Flash Point: Not applicable (solid form)
Flammability: Non-flammable
Stability: Chemically stable under normal conditions
Compatibility: Compatible with a wide range of additives and materials



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air and ensure they are in a well-ventilated area.
If the person is experiencing difficulty breathing, seek medical attention immediately.
If breathing has stopped, administer artificial respiration and seek immediate medical assistance.


Skin Contact:

Remove contaminated clothing and immediately wash the affected area with plenty of soap and water.
If irritation or redness occurs, seek medical advice and show the safety data sheet or product label to the healthcare professional.
In case of extensive or persistent skin contact, seek medical attention.


Eye Contact:

Flush the eyes gently with water for at least 15 minutes, ensuring to remove any contact lenses if present and easy to do so.
Seek immediate medical attention and provide the healthcare professional with the safety data sheet or product label.


Ingestion:

In case of ingestion, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly and drink plenty of water to dilute the substance.
Seek immediate medical attention and provide the healthcare professional with the safety data sheet or product label.


General Advice:

If medical attention is needed, ensure to bring the container or label of the product for easy identification by healthcare professionals.
Do not administer any medication unless instructed to do so by medical personnel.
If a person feels unwell after exposure to Polyglykol 9000 S, it is important to seek medical advice immediately.



HANDLING AND STORAGE


Handling:

Personal Protection:
When handling Polyglykol 9000 S, it is recommended to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing to minimize skin and eye contact.

Ventilation:
Ensure adequate ventilation in the working area to prevent the build-up of vapors or dust.
Use local exhaust ventilation if necessary.

Avoidance of Inhalation:
Avoid inhaling the dust or vapors generated during handling.
Use respiratory protection (e.g., dust mask or respirator) if there is a risk of exposure to airborne particles.

Avoiding Contact:
Avoid direct contact with skin and eyes. In case of contact, promptly rinse the affected area with water and seek medical advice if irritation occurs.

Spill and Leak Procedures:
In the event of a spill or leak, contain the material and prevent it from entering drains, water sources, or soil.
Absorb the spill with an inert material (e.g., sand, vermiculite) and collect it in suitable containers for proper disposal.

Handling Precautions:
Handle Polyglykol 9000 S with care, avoiding rough handling, excessive heat, sparks, or open flames to prevent fire hazards.


Storage:

Storage Conditions:
Store Polyglykol 9000 S in a cool, dry, and well-ventilated area away from direct sunlight, heat sources, and incompatible materials.
Maintain appropriate temperature and humidity conditions to prevent degradation or clumping of the product.

Container Requirements:
Store the chemical in tightly sealed containers made of suitable materials, such as high-density polyethylene (HDPE) or stainless steel, to prevent contamination and moisture ingress.

Proper Labeling:
Clearly label the storage containers with the product name, CAS number (25322-68-3), and any relevant hazard symbols or warnings.

Separation:
Keep Polyglykol 9000 S away from strong oxidizing agents, acids, alkalis, and other incompatible substances to prevent reactions or contamination.

Specific Storage Requirements:
Follow any specific storage recommendations provided by the manufacturer or detailed in the safety data sheet for Polyglykol 9000 S.

Access Control:
Limit access to storage areas to authorized personnel only and ensure they are familiar with proper handling and storage procedures.

Fire Prevention:
Take appropriate fire prevention measures in storage areas, such as using fire-resistant construction, fire extinguishing systems, and storing away from potential ignition sources.



SYNONYMS


PEG 9000 S
Polyethylene glycol 9000
Polyethylene oxide 9000
Carbowax 9000
Macrogol 9000
Polyethylene glycol flake 9000
PEG flake 9000
PEG 9000 solid
Polyglycol solid 9000
PEG 9000S
PEG solid 9000
Polyethylene oxide solid 9000
Carbowax solid 9000
Macrogol solid 9000
Polyethylene glycol MW 9000
PEG MW 9000
PEG 9000S
PEG 9000 flakes
Polyethylene glycol flakes 9000
PEG flakes 9000
Polyethylene glycol solid 9000
PEG solid flakes 9000
Polyethylene oxide flakes 9000
Carbowax flakes 9000
Macrogol flakes 9000
PEG 9000 powder
Polyethylene glycol powder 9000
PEG powder flakes 9000
Polyethylene oxide powder 9000
Carbowax powder 9000
Macrogol powder 9000
Polyglycol MW 9000 solid
PEG MW 9000 solid
Polyglycol 9000S flakes
PEG 9000S powder
Polyethylene glycol MW 9000 solid
PEG MW 9000 flakes
PEG 9000S solid
PEG 9000 granules
Polyethylene glycol granules 9000
PEG granules 9000
Polyglycol granules 9000
PEG 9000 bead form
Polyethylene glycol bead form 9000
PEG bead form 9000


POLYGLYKOL M 500
Polyglykol M 500 is a waxy white to slightly yellowish solid with only a very faint odor at room temperature.
Polyglykol M 500 is the main material to produce polycarboxylate high water reducing agent.
Polyglykol M 500 cellosolve is an organic compound with the formula C5H12O3 used.

CAS Number: 9004-74-4
Molecular Formula: C5H12O3
Molecular Weight: 120.14698
EINECS number: 618-394-3

Polyglykol M 500 is a monomethoxy polyethylene glycol with a molecular weight of 4500 – 5500g/mol.

Polyglykol M 500 is supplied in a heated tanker truck.

Polyglykol M 500 is a monomethoxy polyethylene glycol.
Polyglykol M 500 is a waxy white to slightly yellowish solid at room temperature.
Polyglykol M 500 can be considered a high molecular alcohol and therefore shows the typical chemical reactions of alcohols.

Polyglykol M 500 are used for a wide variety of chemical reactions.
They act as the end cap and hydrophilic component with isocyanates and polyester.
When reacted with unsaturated monomers such as acrylic or methacrylic acid esters, esters are formed, which can be copolymerized to increase hydrophilicity.

Polyglykol M 500 improves the dispersion properties of polymers in water.
Polyglykol M 500 by Clariant is a linear, mono hydroxy-functional, polyethylene glycol monomethyl ether.
Polyglykol M 500 is suitable for paints and coatings.

Polyglykol M 500 can be used as a pore-forming agent to prepare polysulfone membranes with enhanced hydrophilicity.
Poly(ethylene glycol) methyl ether-grafted polyamidoamine (PAMAM) dendrimers can be used as drug carrier systems for anticancer drugs.

Polyglykol M 500 effective cement Good water solubility, wettability, lubricity, physiologically inert properties, irritability.
Polyglykol M 500with medium properties is widely used in the cosmetic and pharmaceutical industries.
Polyglykol M 500 are a series of methyl substituted poly(ethylene) glycols that have been used with some success in the crystallization of a number of hydrophobic proteins.

Polyglykol M 500 is a clear, colorless liquid with an ether-like odor.
Polyglykol M 500 is in a class of solvents known as glycol ethers, noted for their ability to dissolve a variety of substances.

Polyglykol M 500 by Clariant is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG).
Polyglykol M 500 has low diol content to limit formation of crosslinking diesters.
When reacted with unsaturated monomers like acrylic or methacrylic acid, esters are formed which can be copolymerized in order to increase hydrophilicity and improves dispersing properties of polymers in water.

Polyglykol M 500 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates, which are used for the polymerization of polycarboxylate super-plasticizers.
Polyglykol M 500 is a clear neutral liquid at room temperature, and it can be supplied in tank trucks or in steel drums.

Melting point: 60-64 °C
Boiling point: >200°C/760mmHg
Density: 1.094 g/mL at 25 °C
vapor density: >1 (vs air)
vapor pressure: 0.05 mm Hg ( 20 °C)
refractive index: n20/D 1.459
Flash point: 268 °C
storage temp.: -20°C
solubility: H2O: 50 mg/mL at 25 °C, clear, colorless
form: semisolid
Specific Gravity: 1.094
color: White to pale yellow
PH: 5.5-7.0 (25℃, 50mg/mL in H2O)
Water Solubility: Slightly miscible with water.
λmax: λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03
Stability: Stable. Incompatible with strong oxidizing agents, strong acids, strong bases.
InChIKey: XNWFRZJHXBZDAG-UHFFFAOYSA-N
LogP: -0.800 (est)
EWG's Food Scores: 1-3

Polyglykol M 500 PU is a linear, mono hydroxy-functional polyethylene glycol monomethyl ether (M-PEG) that is completely water soluble.
Polyglykol M 500 is esterified with methacrylic acid to yield the corresponding polyglycol mono methacrylates which are used for the polymerization of polycarboxylate superplasticizers.
Polyglykol M 500 is produced for polyurethane applications and offers low alkali and low water content.

Different types of chemical compounds have miscibility with water and other solvents.
Polyglykol M 500 can be formed by nucleophilic attack of methanol on protonated ethylene oxide followed by proton.
Polyglykol M 500 is used as a solvent for many different purposes such as varnishes, paints and resins.

Polyglykol M 500 is also used as an additive in aircraft defrosting solutions.
Polyglykol M 500 is widely used for the synthesis of Vaska complex and related compounds.
Polyglykol M 500 is toxic to bone marrow and testicles.

Those exposed to high levels are at risk for granulocytopenia, macrocytic anemia, oligospermia and azoospermia.
Polyglykol M 500 is converted to methoxyacetic acid (methoxyacetic acid) by alcohol dehydrogenase.
Polyglykol M 500 ethanol and acetate have a protective effect.

Polyglykol M 500 can enter the Krebs cycle where Polyethylene Glycol is present.
Polyglykol M 500 is a group of solvents based on alkyl ethylene glycol or propylene glycol ethers commonly used in paints and cleaners.
Typically, low molecular weight ethers have a higher boiling point with favorable solvent properties.

Uses
Polyglykol M 500 is used as an excipient in many pharmaceutical products, in oral, topical, and parenteral dosage forms.
Polyglykol M 500 is the basis of a number of laxatives (as MiraLax, RestoraLAX, etc.).
Whole bowel irrigation with Polyglykol M 500 and added electrolytes is used for bowel preparation before surgery or colonoscopy or for children with constipation.

Macrogol (with brand names such as Laxido, GoLytely and Miralax) is the generic name for Polyglykol M 500 used as a laxative.
The name may be followed by a number which represents the average molecular weight (e.g. macrogol 3350, macrogol 4000 or macrogol 6000).
The possibility that Polyglykol M 500 could be used to fuse axons is being explored by researchers studying peripheral nerve and spinal cord injury.

Polyglykol M 500 is also commonly used as a polar stationary phase for gas chromatography, as well as a heat transfer fluid in electronic testers.
Polyglykol M 500 is frequently used to preserve waterlogged wood and other organic artifacts that have been salvaged from underwater archaeological contexts, as was the case with the warship Vasa in Stockholm, and similar cases.

Polyglykol M 500 replaces water in wooden objects, making the wood dimensionally stable and preventing warping or shrinking of the wood when it dries.
In addition, Polyglykol M 500 is used when working with green wood as a stabilizer, and to prevent shrinkage.

Polyglykol M 500 is used in various applications such as micelles for drug delivery as well as in modifications of therapeutic proteins to improve their pharmacokinetics.
Polyglykol M 500's mild surfactant properties are employed in shampoos, body washes, and cleansing products.
Polyglykol M 500 can be found in hair care products for its conditioning and anti-static effects.

Polyglykol M 500 is used as a solvent or diluent in adhesive formulations.
Polyglykol M 500 is added to coatings to improve flow, leveling, and texture.
Polyglykol M 500 is used to stabilize solutions and dispersions in laboratory settings.

Polyglykol M 500 applied in the functionalization and modification of nanoparticles, particularly in the medical and materials science fields.
Certain PEG derivatives, including Polyglykol M 500, are used as contrast agents in medical imaging techniques like MRI.
Polyglykol M 500 is used in the development of biomaterials for tissue engineering and drug delivery.

Polyglykol M 500 derivatives are approved as food additives, stabilizers, and texturizing agents in certain food and beverage products.
Polyglykol M 500 derivatives are investigated for their potential use in wastewater treatment due to their ability to adsorb contaminants and improve Polyglykol M 500 can enhance the solubility of poorly water-soluble drugs, making them easier to formulate into medications.

Polyglykol M 500 derivatives are often used in drug delivery systems to improve the release profile of drugs and increase their bioavailability.
Polyglykol M 500 can be found in ointments, creams, and lotions due to its ability to improve the texture and spreadability of these products.
In the cosmetics and personal care industry, Polyglykol M 500 is used for its emollient and solubilizing properties:

Polyglykol M 500 can help stabilize oil-in-water emulsions, which are common in creams, lotions, and other cosmetic products.
Polyglykol M 500 can act as a mild surfactant in cleansing products like shampoos, body washes, and facial cleansers.
Polyglykol M 500 can be used in skincare products to provide moisturization and improve the texture of the product.

Polyglykol M 500 is used in various industrial applications due to its solubility and non-reactive nature:
Polyglykol M 500 can be used as a solvent or diluent in adhesive formulations.
Polyglykol M 500 can contribute to the properties of coatings, such as improved flow and leveling.

In laboratory settings, Polyglykol M 500 might be used as a component in various solutions or as a stabilizing agent.
Polyglykol M 500 nanoparticles are utilized for targeted drug delivery, enhancing drug accumulation in specific tissues while minimizing side effects.
Polyglykol M 500 is used in textile dyeing and finishing processes to enhance dye penetration and improve fabric properties.

Polyglykol M 500 and other PEG derivatives are used as stabilizers and excipients in a wide range of products:
Polyglykol M 500 derivatives are approved for use as food additives and stabilizers in certain food and beverage products.
Polyglykol M 500 derivatives can serve as emulsifiers, thickeners, and stabilizers in cosmetics, skincare products, and toiletries.

Polyglykol M 500 can be used in pesticide formulations to improve the dispersion of active ingredients and enhance their effectiveness.
Polyglykol M 500 can be added to paint formulations to improve the stability of pigments, enhance paint flow, and reduce defects.
Polyglykol M 500 can be present in household cleaners and disinfectants, aiding in solubilizing active ingredients and improving cleaning performance.

Polyglykol M 500's used in some personal hygiene products like soaps and hand sanitizers for its emulsifying and cleansing properties.
Polyglykol M 500 can be used in industrial degreasing formulations due to its ability to solubilize oils and greases.
Polyglykol M 500 is used in textile dyeing and printing processes to improve dye dispersion and color uptake.

Safety
Polyglykol M 500, especially in its concentrated form, can cause skin irritation in some individuals.
Sensitization reactions, where the skin becomes hypersensitive upon repeated exposure, can occur in susceptible individuals.
Polyglykol M 500 can cause irritation to the eyes upon direct contact.

In case of eye contact, thorough rinsing with water is recommended.
Inhalation of vapor, mist, or aerosolized forms of Polyglykol M 500 should be minimized, especially in confined spaces without proper ventilation
Some individuals may be allergic to Polyglykol M 500, which can lead to various adverse reactions upon exposure.

Synonyms
Methoxypolyethylene Glycols
Poly(oxy-1,2-ethanediyl),a-methyl-w-hydroxyPolyglykol M 500
MPEG
Glycols,polyethylene, monomethyl ether
M 550
M 750
MPEG
MPEG 1000
MPEG 10000
MPEG 2000
MPEG 2000HQ
MPEG 350
MPEG 500
MPEG 5000
MPEG 550
MPEG 700
MPEG 750
MPEG 950
MPG
MPG 025
MPG 081
MPG 130
MPG 130H
MPG140
Marlipal 1/12
Me-PEG 400
Methoxy PEG 1000
Methoxy PEG 400
Methoxy PEG4000
Methoxypoly(ethylene glycol)
Methyl Polyglycol
Monomethoxypoly(ethylene oxide)
Monomethoxypolyethylene Glycol
Monomethoxypolyoxyethylene
Nissan Uniol 1000
Nissan Uniol 550
Nissan Uniox M1000
Nissan Uniox M 2000
Nissan Uniox M 400
Nissan Uniox M 4000
NissanUniox M 500
Nissan Uniox M 550
Nissan Uniox M 600
O-Methoxypolyethyleneglycol
PEG-MME
PEM 700N
Pluriol 350E
Pluriol 500
Pluriol 750
Pluriol A1000E
Pluriol A 2000
Pluriol A 2000E
Pluriol A 2030E
Pluriol A 275E
Pluriol A 350E
Pluriol A 500
Pluriol A 500E
Pluriol A 5010E
Pluriol A 750E
Pluriol A 750I
Poly(ethylene oxide) Monomethyl Ether
Polyethylene Glycolmethyl Ether
Polyethyleneglycol Monomethyl Ether
Polyglycol M 1000
POLYHEXAMETHYLENE BIGUANIDE
Polyhexamethylene Biguanide Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use,[2] it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide.[3] Polyhexamethylene biguanide has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).[4] Some products containing Polyhexamethylene biguanide are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.[5] Polyhexamethylene biguanide eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.[6] Branded as Baquacil, it also has an application as a swimming-pool and spa water sanitizer in place of chlorine- or bromine-based products. It is available as Baqua-Spa 3 sanitize, as Revacil Spa 3 sanitizer, and in the Leisure Time Free system. Polyhexamethylene biguanide is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products. It is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors. The Polyhexamethylene biguanide hydrochloride salt (solution) is used in the majority of formulations. Safety In 2011, Polyhexamethylenbiguanide (Polyhexamethylene biguanide, Polyhexanide) has been classified as carcinogenic category 2 by the European Chemical Agency (ECHA). Products containing concentrations of 1% Polyhexamethylene biguanide and more have to be declared as «suspected of causing cancer» and concentrations of 0.1% or above have to be noted in the safety datasheet. Polyhexamethylene biguanide is allowed as a part of cosmetic products (max. 0.1%) if exposure by inhalation is impossible. On the 20th of April 2018, the european commission decided to ban preservative uses of Polyhexamethylene biguanide PT9 (Fibre, leather, rubber and polymerised materials preservatives). It’s still allowed for uses as disinfectants PT2 (Disinfectants and algaecides not intended for direct application to humans or animals). Furthermore, Polyhexamethylene biguanide has been declared as a candidate for substitution by the ECHA. Studies suggest that iodine’s mechanism of action is through destabilization of the bacterial cell wall and disruption of the membrane that results in leakage of the intracellular components.25 Polyhexamethylene biguanide (PHMB). Polyhexamethylene biguanide (PHMB), also known as polyhexanide and polyaminopropyl biguanide, is a commonly used antiseptic. It is used in a variety of products including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners. Wound care products containing Polyhexamethylene biguanide include Kerlix AMD™, Excilon AMD™, and Telfa AMD™ (all from Tyco HealthCare Group, Mansfield, Mass) and XCell® Cellulose Wound Dressing Antimicrobial (Xylos Corp, Langhorne, Pa). A review of the literature demonstrates in-vivo and in-vitro safety and effectiveness of Polyhexamethylene biguanide for a number of applications. For wound dressings, Wright and colleagues26 compared the effectiveness of a silver dressing to a dry gauze dressing containing Polyhexamethylene biguanide (Kerlix AMD). Results demonstrated reduction in bioburden with both dressings when tested in an in-vitro bactericidal assay. Using a Kirby-Bauer zone of inhibition study, the gauze was not as effective. This was believed to be due to a tight bond between the dressing and Polyhexamethylene biguanide, which was not released and therefore did not result in killing beyond the edge of the dressing.26 Alternatively, Motta and associates6 demonstrated a good response using Kerlix AMD compared to gauze without Polyhexamethylene biguanide in wounds where packing the dressing into the wound was required. Results suggested that the Polyhexamethylene biguanide in the gauze resulted in a decrease in the number of organisms present in the wound. The majority of literature describes effectiveness of Polyhexamethylene biguanide on various microorganisms associated with contact lens disinfecting solutions. Antimicrobial effectiveness has been demonstrated on Acanthamoeba polyphaga, A castellanii, and A hatchetti.25,27,28 Additional effectiveness was demonstrated for Polyhexamethylene biguanide use in water treatment. Barker and colleagues29 tested the effect of Polyhexamethylene biguanide on Legionella pneumophila. This bacterium causes Legionnaire’s disease and can be found in water systems, air conditioning machinery, and cooling towers. Gilbert and colleagues30,31 have performed numerous studies on bacteria, especially those that form biofilms, such as Klebsiella pneumoniae. In studying biofilms produced from E coli and S epidermidis, they noted that those compounds with higher activity against planktonic bacteria, including Polyhexamethylene biguanide, were also the most effective agents against sessile bacteria found within biofilms. They suggested that the differences in effects of concentration of Polyhexamethylene biguanide on planktonic versus sessile bacteria was due to either the mechanism of action or the number or disposition of cationic binding sites.30–32 Kramer et al33 have studied the effects of various antiseptics including Polyhexamethylene biguanide on fibroblast proliferation and cytotoxicity. They noted that while octenidine-based products retarded wound healing, Polyhexamethylene biguanide promoted contraction and aided wound closure significantly more than octenidine and placebo. The mechanism of action of Polyhexamethylene biguanide has been described in a number of articles. Broxton et al34,35 demonstrated that maximal activity of the Polyhexamethylene biguanide occurs at between pH 5–6 and that initially the biocide interacts with the surface of the bacteria and then is transferred to the cytoplasm and cytoplasmic membrane. Ikeda and colleagues36 showed that the cationic Polyhexamethylene biguanide had little effect on neutral phospholipids in the bacterial membrane—its effect was mainly on the acidic negatively charged species where it induced aggregation leading to increased fluidity and permeability. This results in the release of lipopolysaccharides from the outer membrane, potassium ion efflux, and eventual organism death.37 Clinically, Polyhexamethylene biguanide has been used as a perioperative cleansing agent,38 in mouth wash,39 in ophthalmology,38,40 and as a topical wash.18 Hohaus et al19 reported on the oral use of Polyhexamethylene biguanide (Lavasept 1%, Fresenius-Kabi, Bad Homburg, Germany). A combination of oral terbinafine and topical ciclopirox and Polyhexamethylene biguanide were used to successfully treat a deep fungal infection (Trichophyton mentagrophytes) of the throat. Petrou-Binder40 describes the germicidal effects of Polyhexamethylene biguanide (Lavasept 0.02%) as eye drops prior to cataract surgery. It was well tolerated with low tissue response and minimal patient discomfort. While there is no peer-reviewed clinical literature of Polyhexamethylene biguanide used on wounds, industry literature describes the effectiveness of AMD Gauze (Kerlix) as a bacterial barrier against Staphylococcus epidermidis (penicillin resistant) on volunteers. Results suggest that clinically, this dressing was an effective barrier against bacterial colonization.41 The studies suggested that AMD gauze did not elicit any skin reactions.42 Biosynthesized Cellulose Wound Dressing— Antimicrobial (BWD-Polyhexamethylene biguanide) Biosynthesized cellulose wound dressings (XCell Cellulose Wound Dressing and XCell Cellulose Wound Dressing Antimicrobial) were developed to maintain a moist wound environment without causing maceration, reduce pain, and enable autolytic debridement. This is possible because the dressings effectively absorb exudate and hydrate dry areas of a wound different from other dressings that have only a single function.43 A 49-patient, multicenter, controlled, randomized clinical study was conducted to demonstrate effectiveness of BWD compared to standard of care on venous leg ulcers. Significantly more autolytic debridement, significantly reduced pain, and cleaner wound margins were demonstrated after the 12-week study period.44,45 Improved rate of wound closure, as demonstrated by increased epithelialization and granulation tissue, was also noted.43 The antimicrobial version of BWD (BWD-Polyhexamethylene biguanide) contains cellulose, water, and 0.3% polyhexamethylene biguanide (PHMB). BWD-Polyhexamethylene biguanide is indicated for use on partial- and full-thickness wounds. It is designed to cover a wound or burn, absorb areas of wound exudate, and provide a moist wound environment that supports autolytic debridement of nonviable tissue. The dressing may be used on moderately exuding, nonexuding, and dry wounds. It also protects against abrasion, desiccation, and external contamination. The moist environment has a cooling effect that has demonstrated a significant reduction of pain.45 Preclinical efficacy testing. BWD-Polyhexamethylene biguanide demonstrates it effectiveness against a variety of organisms. Following a modified American Association of Textile Chemists and Colorists (AATCC) Method 100, samples were incubated with approximately 106 CFU/mL of the various challenge organisms. After 24 hours, a second count was made to determine the reduction in the number of organisms present. Results indicated 99.9% reduction of MRSA, Escherichia coli, Enterococcus faecalis, Bacillus subtilis, and Candida albicans within the 24-hour period. Release of Polyhexamethylene biguanide from BWD-Polyhexamethylene biguanide. A study was performed to demonstrate the release of Polyhexamethylene biguanide from BWD-Polyhexamethylene biguanide. Five sterile 3.5-in x 3.5-in samples were used. One quarter of the dressing was used to determine the initial Polyhexamethylene biguanide concentration in each dressing using UV-Vis (Ultraviolet-Visible) Spectroscopy (Genesys™ 10 UV, Thermo Spectronic, Rochester, NY) at a wavelength of 234 nm. The remainder of the sample was weighed and placed into 20 times its weight in filtered water. At various times, including 0.5, 1, 2, 3, 4, 5, 6, and 24 h, the solution was assayed for Polyhexamethylene biguanide concentration. At the 24-h time the dressing was removed from the tray, weighed, and an extract was taken and assayed for Polyhexamethylene biguanide concentration. Figure 1 illustrates the concentration of Polyhexamethylene biguanide over time. Equilibrium was reached after about 3 hours with the concentration (in ppm) in the dressing equaling the concentration in the solution. This demonstrates that the Polyhexamethylene biguanide is not bound to the cellulose and therefore can be released into surrounding fluid along a concentration gradient. Clinical case series. BWD-Polyhexamethylene biguanide was evaluated in an open enrollment, noncontrolled clinical trial. Standard procedures for wound care were followed and samples of wound fluid were tested for type and level of microbial colonization at initial administration and 1–7 days after BWD-Polyhexamethylene biguanide placement. Materials and Methods BWD-Polyhexamethylene biguanide pads (XCell Cellulose Wound Dressing–Antimicrobial) measuring 3.5-in x 3.5-in were provided to 2 clinical sites and used as the primary dressing. Secondary dressings, including compression wraps (where indicated), were the standard of care for the facilities. Patients were chosen on an “as needed” basis and neither randomized nor controlled. The 2 sites evaluated a total of 12 patients with 26 wounds of various etiologies including venous stasis ulcers (12), diabetic (4), traumatic (8), vasculitic (1), and necrobiosis diabetica lipoidica (1). Eleven of the 12 patients were unresponsive to a silver impregnated or an iodine containing dressing in the 3–4 weeks prior to use of the BWD-Polyhexamethylene biguanide dressing. In these cases the wound had either increased in size or failed to progress. One patient was treated directly with BWD-Polyhexamethylene biguanide. Swabs of the wound were taken to determine if bacterial colonization was the reason for the lack of response to previous dressings. Organisms were identified in the wounds of 8 patients prior to and after BWD-Polyhexamethylene biguanide application. Systemic antibiotics were not given in conjunction with the use of BWD-Polyhexamethylene biguanide to ensure bacterial reductions were solely due to the Polyhexamethylene biguanide. The organisms identified included methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus aureus, Pseudomonas aeruginosa, Proteus mirabilis, Diphtheroid gram-positive rods, beta hemolytic Streptococcus B, Enterobacter aerogenes, mixed skin flora, and Enterococcus sp. The most common was Staphylococcus (including MRSA) and Pseudomonas. Semiquantitative scores ranged from 0 to 4+ (0 represents no bacterial growth and 4+ represents the largest amount of bacterial growth on the culture). The various bacteria found in the wounds of all 8 patients and the relative abundance prior to and after application of the BWD-Polyhexamethylene biguanide dressing are shown in Table 1. Results Four patients (5 wounds) from 1 site were used strictly for the economic analysis below. Of the remaining 8, 1 patient (3 wounds) was lost to follow-up after 1 week of BWD-Polyhexamethylene biguanide treatment. The remaining patients had BWD-Polyhexamethylene biguanide applied over periods of 1 to 7 weeks. Results of the 8 patients demonstrated a decrease in wound size on average from 6.79 cm2 to 4.57 cm2 (42% reduction) in an average of 25 days (Table 2). Two of the wounds completely healed during the study, 13 improved, and 2 showed a slight increase in size. Case Reports Case 1. A 58-year old woman presented with a full-thickness draining wound over the dorsal foot secondary to an incision (Figure 2). The patient's wound extended to the level of tendon and was recalcitrant to topical gels, ointments, foam dressings, silver dressings, and moist saline gauze. Past medical history was significant for Hodgkin’s disease, heart valve replacement, pacemaker, hemolytic anemia, and chemo and radiation therapy for breast cancer, which was on-going at the time of presentation. After 3 weeks of treatment with a papain-urea ointment (Panafil®, Healthpoint, Fort Worth, Tex), the majority of fibrotic tissue was removed although the wound did not decrease in size. The patient was then placed exclusively on BWD-Polyhexamethylene biguanide for approximately 4 weeks with the dressing being changed once a week. The wound rapidly improved and progressed to complete closure during this time period. Case 2. A 78-year-old woman presented with a large wound secondary to a hematoma occurring after trauma (Figure 3). The patient was not on anticoagulants and had a medical history significant for hypertension. The wound had been present for 1 week prior to presentation. Following extensive debridement, the patient was started exclusively on BWD-Polyhexamethylene biguanide dressing changes every 4 days. The wound closed completely in approximately 2 months. The patient had a history of similar lesions that required up to 6 months of treatment. Case 3. An 89-year-old woman with diabetes presented with venous disease and psoriasis (Figure 4). She had 2 wounds, one each on her right and left lower extremities (RLE and LLE) that were treated separately over a period of 209 days. Upon presentation, the RLE wound was 17.5 cm x 7.0 cm x 0.3 cm. It was treated for 167 days using various products including Acticoat™ (46 applications, [Smith & Nephew, Largo, Fla]), Santyl® (7 applications, [Healthpoint, Fort Worth, Tex]), Apligraf® (6 applications, [Organogenesis, Canton, Mass]), and Xeroform™ (7 applications, [Tyco-Kendall HealthCare Group, Mansfield, Mass]). After these treatments the wound measured 9.0 cm x 4.4 cm x 0.1 cm. Following an initial decrease in size, the wound became unresponsive to these treatments. At that time, BWD-Polyhexamethylene biguanide was substituted as the exclusive primary dressing. Over the next 42 days, a total of 10 BWD-Polyhexamethylene biguanide dressings were applied. The patient subsequently went on to heal 1 week after her final treatment (49 days total) using this protocol. Upon presentation, the LLE wound was 1.0 cm x 0.9 cm x 0.3 cm. It was treated for 156 days using various products including Acticoat (2 applications), XCell (2 applications), Santyl/Panafil (70 applications), Apligraf (4 applications), Sulfamylon (26 applications), Aquacel® (3 applications, [ConvaTec, Skillman, NJ]), OpSite™ (8 applications, [Smith & Nephew, Largo, Fla]), and Xeroform (7 applications). The wound remained unhealed after these treatments. The wound was recalcitrant to care; therefore, BWD-Polyhexamethylene biguanide was substituted as the exclusive primary dressing. Over the next 53 days, a total of 12 BWD-Polyhexamethylene biguanide dressings were applied as the exclusive treatment. The wound healed at approximately 60 days. Case 4. A 79-year-old woman presented with venous leg ulcer on her lower extremity (Figure 5). She was treated over a period of 104 days. The wound was 15.0 cm x 9.0 cm x 0.1 cm. The wound was initially treated for 34 days using Panafil (13 applications) and Iodosorb (22 applications). After these treatments the wound measured 10.0 cm x 9.0 cm x 0.3 cm. The wound was determined to be recalcitrant after an initial decrease in size (15.0 cm x 9.0 cm to 10.0 cm x 9.0 cm, [≈ 35%]) and BWD-Polyhexamethylene biguanide was substituted as the exclusive primary dressing. Over the next 70 days, a total of 10 BWD-Polyhexamethylene biguanide dressings were applied. Effect on wound bioburden and pain. By evaluating the bacterial load pre- and post-BWD-Polyhexamethylene biguanide, it was demonstrated that the dressing resulted in elimination of Pseudomonas aeruginosa, Diptheroid gram-positive rods, beta hemolytic streptococcus, and Enterobacter aerogenes in some patients. In other patients, decreased levels of Staphylococcus aureus, Pseudomonas aeruginosa, and Proteus mirabilis were observed. A reduction in pain has been noted with BWD44 as was observed in the present study. Economics of BWD-Polyhexamethylene biguanide. The estimated cost for the treatment of chronic wounds including services and associated products is close to $40,000 or in some cases even more.45 Any delay to heal a wound can increase that cost. Mulder46 described an economic model for determining the cost of 2 different treatments for removing necrotic tissue. The analysis demonstrated that a hydrogel/polyurethane combination was slightly more expensive than wet-to-dry gauze but was more cost effective when time to reach ≥ 50% debridement was included. The cost of BWD-Polyhexamethylene biguanide is similar to other advanced wound dressings. An economic analysis was performed in this study to determine the cost of BWD-Polyhexamethylene biguanide use over time. An economic analysis of the use of BWD-Polyhexamethylene biguanide dressings demonstrates the low cost of using BWD-Polyhexamethylene biguanide on recalcitrant wounds. The average cost of material was calculated to be $5.99 to $9.01 per day with the wounds demonstrating improvement or healing. No attempt was made to quantify the remaining cost of treatment (clinic visit, staff time, etc.). Data were gathered retrospectively for 2 patients that presented at the UCSD Healthcare System in San Diego, Calif. These patients had a total of 3 wounds that were initially treated with an array of advanced wound care products prior to exclusive use of a BWD-Polyhexamethylene biguanide dressing. The costs associated with the products used in Cases 3 and 4 appear in Tables 3 and 4, respectively. Table 5 illustrates the cost of the use of BWD-Polyhexamethylene biguanide including the use of saline and gauze to clean the wound. Conclusion A greater understanding of the role bacteria plays in the wound matrix repair process is resulting in an increasingly important role for antimicrobial dressings and products used in chronic wound care. The differences between various antimicrobial components and dressings require that clinicians have a basic understanding of different antimicrobial agents and their role in tissue repair before selecting the most appropriate dressing for a wound. The introduction of noncytotoxic levels of antimicrobial agents, including silver and Polyhexamethylene biguanide, provides a means to potentially decrease levels of bacterial colonization that may impede closure while providing dressings that may assist with the development of a wound environment conducive to tissue repair, and ultimately, successful wound closure. Currently, Polyhexamethylene biguanide does not have a history of resistance or cytotoxicity, has demonstrated promotion of healing,33 and may play a new and important role as an antimicrobial agent in dressings. The need for decreased frequency of dressing changes, dressing tolerance, and ease-of-use are factors, which are equally important when selecting an appropriate antimicrobial dressing. The limited amount of information on the ability of antimicrobial dressings to significantly affect the healing process and wound closure supports the need for well designed and adequately powered clinical trials to determine the true role of these devices in the treatment of chronic wounds. Current information and publications indicate a potential benefit regarding the use of these products in wounds where bacterial burden may be delaying or impeding wound closure. Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in a variety of products including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners. There are regulatory concerns with regard to its safety in humans for water treatment. We decided to assess the safety of this chemical in Sprague-Dawley rats. Polyhexamethylene biguanide was administered in a single dose by gavage via a stomach tube as per the manufacturer's instruction within a dose range of 2 mg/kg to 40 mg/kg. Subchronic toxicity studies were also conducted at doses of 2 mg/kg, 8 mg/kg and 32 mg/kg body weight and hematological, biochemical and histopathological findings of the major organs were assessed. Administration of a dose of 25.6 mg/kg, i.e. 1.6 mL of 0.4% Polyhexamethylene biguanide solution (equivalent to 6.4x103 mg/L of 0.1% solution) resulted in 50% mortality. Histopathological analysis in the acute toxicity studies showed that no histopathological lesions were observed in the heart and kidney samples but 30% of the animals had mild hydropic changes in zone 1 of their liver samples, while at a dosage of 32 mg/kg in the subchronic toxicity studies, 50% of the animals showed either mild hepatocyte cytolysis with or without lymphocyte infiltration and feathery degeneration. Lymphocyte infiltration was, for the first time, observed in one heart sample, whereas one kidney sample showed mild tubular damage. The acute studies showed that the median lethal dose (LD50) is 25.6 mg/kg (LC50 of 1.6 mL of 0.4% Polyhexamethylene biguanide. Subchronic toxicological studies also revealed few deleterious effects on the internal organs examined, as seen from the results of the biochemical parameters evaluated. These results have implications for the use of Polyhexamethylene biguanide to make water potable. Keywords: polyhexamethylene biguanide, toxicity, biochemical hematology, histopathology, LD50, therapeutic index Introduction Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in several ways including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners. It is also known as polyhexanide and polyaminopropyl biguanide, polymeric biguanide hydrochloride; polyhexanide biguanide. It is a commonly applied antiseptic, often used as a preservative in cosmetics and personal care products (Schnuch et al., 2007). The antimicrobial efficacy has been demonstrated on Acanthamoeba polyphaga, A castellanii, and A hatchetti (Hughes et al., 2003; Wright et al., 2003; Burgers et al., 1994; Hiti et al., 2002). In vivo studies have also demonstrated that a miltefosine–polyhexamethylene biguanide combination is highly effective for the treatment of Acanthamoeba keratitis (Polat et al., 2013). As a biocide, additional pharmacological effects have been demonstrated against Legionella pneumophila, against gram positive and gram negative bacteria. It is a broad spectrum virucide and has amebicidal activities (Gilbert et al., 1990; Kramer et al., 2004; Broxton et al., 1984; Lee et al., 2007). Polyhexamethylene biguanide retains its activity in hard water and does not cause surface streaks or tackiness (Broxton et al., 1984b; Ikeda et al., 1984). Consistent with previous studies, a Polyhexamethylene biguanide mouthrinse was shown to inhibit plaque re-growth and reduced oral bacterial counts, indicating that Polyhexamethylene biguanide could be an alternative to established mouth rinses in preventive applications (Welk et al., 2005). Recreational water maintained and sanitized with Polyhexamethylene biguanide is however assumed to serve as a medium for transmission of ocular adenovirus infections, mainly because at a concentration of 50 ppm, Polyhexamethylene biguanide was not virucidal against adenovirus at temperatures consistent with swimming pools or hot tubs (Romanowski et al., 2013). Previous studies have shown increased frequency of sensitization to 0.5% and 0.4% Polyhexamethylene biguanide in unselected dermatitis patients (Schnuch et al., 2007). Polyhexamethylene biguanide proved also toxic to keratocytes (Lee et al., 2007) and was shown to have acute toxic effects in human cells where it caused severe inflammation, atherogenesis, and aging. Moreover, Polyhexamethylene biguanide produced embryo toxicity and heart failure in zebrafish (Kim et al., 2013). Though, officially not used in the treatment of drinking water, there have been instances where toxic effects were experienced in certain individuals. For example in the period from August 2006 to May 2007, more than 12,500 patients were admitted to hospital with a history of drinking illegal cheap “vodka” in 44 different regions in Russia, of whom 9.4% died. In reality, the “vodka” was an antiseptic liquid composed of ethanol (≈93%), diethyl phthalate, and 0.1-0.14% polyhexamethylene guanidine (PHMG) (“Extrasept-1”) (Ostapenko et al., 2011). Previous studies have also shown that another biocide – polyhexamethylene guanidine hydrochloride – has an LD50 of 600 mg/kg in rats (Asiedu-Gyekye et al., 2014). There have been various regulatory concerns with regard to the use of these biocides in water treatment. We therefore evaluated the safety of Polyhexamethylene biguanide when used in treating water to make it potable and also in the case of survivors of drowning events, concentrating especially on its effect on the major organs. Materials and methods Polyhexamethylene biguanide concentrate was purchased from AGRIMAT-Ghana as an aqueous solution. A stock solution of 0.1% concentration of Polyhexamethylene biguanide was prepared using deionized water. This was equivalent to 1.0 mg/mL of Polyhexamethylene biguanide. Further dilutions were made using deionized water. Animal husbandry and groupings Eight-week-old Sprague-Dawley rats (250 g body weight) of both sexes were acquired from Noguchi Memorial Institute for Medical Research, University of Ghana, Legon and housed in rooms with regulated room temperature of 26°C and humidity of 40 to 60%. The animals were exposed to 12 h light and 12 h darkness. The females were nulliparous and non-pregnant. The animals were randomly assigned to 4 groups of 10 animals each for the acute toxicity test. A similar provision was made for the subchronic study. Animal feed (Kosher Feed Mills Ltd, Osu, Accra) and water were given ad libitum. To ensure effective absorption from the gastrointestinal tract after oral administration, feed was withdrawn 8 h prior to treatment and further withheld for an extra 30 min after administration of Polyhexamethylene biguanide before being reintroduced. Equal numbers of rats were randomized and each marked in their individual cages for 7 days prior to Polyhexamethylene biguanide administration. Equal numbers of animals of both sexes were used at each dose level of Polyhexamethylene biguanide. Acute toxicity Polyhexamethylene biguanide was administered as a single dose by gavage in view of the potential mode of ingestion. The animals received doses of 2 mg/kg (500 mg/L), 4 mg/kg (2000 mg/L), 32 mg/kg (8000 mg/L) and 40 mg/kg (10000 mg/L of 0.1% Polyhexamethylene biguanide solution). Since the maximum volume of liquid that could be administered was 1 mL/100 g of body weight, an appropriate adjustment was made in preparing the concentrations so as to avoid exceeding the recommended volume of not more than 2 mL for oral administration (Lee, 1985). Thus 5 different concentrations were prepared. Control animals received only deionized water. The animals were observed every 30 min for the first 4 h, and every 8 h for the next 24 h. The number of animals that died within the 24 h period was recorded for each treatment. The rest of the animals were observed daily for 14 days and any clinical signs were recorded. Clinical signs monitored included respiratory distress, frequency of urination, swellings, abnormal gait, etc. Discussion This study aimed to assess the safety level of Polyhexamethylene biguanide when used to sanitize water to make it potable. The LD50 calculated from the study was found to be 25.6 mg/kg (equivalent to 6.4x103 mg/L of 0.1% Polyhexamethylene biguanide solution). Blood chemistry studies also indicated little or no adverse reaction on cellular components of the blood. All the indices examined were comparable to those of controls, suggesting that the chemical may not have any adverse effects on cellular components of the blood at doses below 25.6 mg/kg, the dose which elicited LD50. Potassium concentrations detected were very high compared to controls, p<0.0057, suggesting that at LD50 level most of the rats might have experienced abnormal heart beats, but this was not confirmed by the histopathological study on the heart as there were no cellular lesions detected. This finding may suggest that in spite of the high dose tested, which possibly might have caused abnormal heart beat in some animals, the integrity of the architecture of the vital organs was not compromised. This observation is similar to that made for PHMGH (Asiedu-Gyekye et al., 2014). Sodium concentrations, on the other hand, did not show any change in either Polyhexamethylene biguanide-treated or control groups (p<0.08), thus most of the clinical manifestations such as lethargy, weakness, etc, usually associated with sodium imbalance were not observed in the study. It is worth noting that most of the animals that died exhibited various nervous manifestations such as abnormal gait and tonic-clonic convulsions. These observations were not supported by the electrolyte profile obtained from blood chemistry analysis. A chronic toxicity study, which is beyond the goal of this study, is recommended to be carried out to further investigate this nervous phenomenon. It should be emphasized that mortality only occurred at very high doses.
POLYHEXAMETHYLENE BIGUANIDE HCL
Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria.


CAS Number: 32289-58-0; 27083-27-8
EC Number: 1308068-626-2
Chemical Name:Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride
Chemical Formula: (C8H17N5)n•(HCl)x



SYNONYMS:
biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB (Poly Hexa Methylene Biguanide), Polyhexamethylene biguanidine Hydrochloride, Pure Polyhexamethylene biguanide Hydrochloride (PHMB) CAS 32289-58-0, Poly(hexamethylenebiguanide) Hcl, Poly(hexamethylenebiguanide)hydrochloride,
Polyhexamethylene biguanide, Polyhexamethylene guanide, Poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) Hydrochloride, Poly(hexamethylenebiguanide), Polihexanide, Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB(Poly Hexa Methylene Biguanide), Polyhexanide hydrochloride, Polyhexamethylene biguanide hydrochloride, 1-(diaminomethylidene)-2-hexylguanidine hydrochloride, PHMB; Polyhexamethylene biguanide, Poly(hexamethylene) biguanide hydrochloride, Polyhexamethylene biguanide hydrochloride, Poly(iminoimidocarbonyl)iminohexamethylene hydrochloride, N,N'''-1,6-Hexanediylbis(N'-cyanoguanidine) hexamethylenediamine polymer hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB (Poly Hexa Methylene Biguanide), Polyhexamethylene biguanidine Hydrochloride, Pure Polyhexamethylene biguanide Hydrochloride (PHMB) CAS 32289-58-0, Poly(hexamethylenebiguanide) Hcl, Poly(hexamethylenebiguanide)hydrochloride, Polyhexamethylene biguanide, Polyhexamethylene guanide, Poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) Hydrochloride, Poly(hexamethylenebiguanide), Polihexanide, Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB(Poly Hexa Methylene Biguanide), Polyhexanide hydrochloride, Polyhexamethylene biguanide hydrochloride, 1-(diaminomethylidene)-2-hexylguanidine hydrochloride, PHMB; Polyhexamethylene biguanide, Poly(hexamethylene) biguanide hydrochloride, Polyhexamethylene biguanide hydrochloride, Poly(iminoimidocarbonyl)iminohexamethylene hydrochloride, N,N'''-1,6-Hexanediylbis(N'-cyanoguanidine) hexamethylenediamine polymer hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB(Poly Hexa Methylene Biguanide), Polyhexamethylene biguanidine Hydrochloride,




Polyhexamethylene Biguanide HCL is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria.
Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.


Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene Biguanide HCL is a polymer applied as a disinfectant and antiseptic.


Polyhexamethylene Biguanide HCL is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria.
Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.


Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene Biguanide HCL renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene Biguanide HCL is available also as 20% aqueous solution.


Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene Biguanide HCL is a polymer applied as a disinfectant and antiseptic.
In dermatological use, Polyhexamethylene Biguanide HCL is also called polihexanide.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene Biguanide HCL renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene Biguanide HCL is available also as 20% aqueous solution.


Polyhexamethylene Biguanide HCL is an antimicrobial agent that kills or inhibits the growth of bacteria, fungi, and other microorganisms.
Polyhexamethylene Biguanide HCL is also effective against a wide range of viruses, including influenza and hepatitis.
Polyhexamethylene Biguanide HCL has been used in wet wipes for many years and is considered to be safe and effective.


The bactericidal ability of Polyhexamethylene Biguanide HCL is better than other bactericides.
In particular, Polyhexamethylene Biguanide HCL's unique long-term antibacterial effect and the ability to prevent secondary infection are not achieved by other fungicides.


Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene Biguanide HCL is a polymer applied as a disinfectant and antiseptic.
In dermatological use, Polyhexamethylene Biguanide HCL is also called polihexanide.


Polyhexamethylene Biguanide HCL is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


The solution of Polyhexamethylene Biguanide HCL is an important ingredient in some pharmaceutical or veterinary formulations.
Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene Biguanide HCL renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene Biguanide HCL is available also as 20% aqueous solution.


Polyhexamethylene Biguanide HCL is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


The solution of Polyhexamethylene Biguanide HCL is an important ingredient in some pharmaceutical or veterinary formulations.
Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


Polyhexamethylene Biguanide HCL is best known for its broad-spectrum antimicrobial and antifungal activity.
Polyhexamethylene Biguanide HCL is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions.
Polyhexamethylene Biguanide HCL is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.


Polyhexamethylene Biguanide HCL is a polymer used as a disinfectant and antiseptic.
Polyhexamethylene Biguanide HCL has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene Biguanide HCL renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene Biguanide HCL is available also as 20% aqueous solution.


Polyhexamethylene Biguanide HCL is best known for its broad-spectrum antimicrobial and antifungal activity.
Polyhexamethylene Biguanide HCL is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions.


Polyhexamethylene Biguanide HCL is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.
Polyhexamethylene Biguanide HCL is a polymer used as a disinfectant and antiseptic.


Polyhexamethylene Biguanide HCL has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


Polyhexamethylene Biguanide HCL is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene Biguanide HCL is a polymer applied as a disinfectant and antiseptic.



USES and APPLICATIONS of POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL can be widely applied in the fields of daily chemical industry, water treatment, textile, papermaking, petroleum, agriculture, husbandry, health care etc.


Polyhexamethylene Biguanide HCL can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.


Polyhexamethylene Biguanide HCL is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.
Polyhexamethylene Biguanide HCL can be widely used in textile, animal husbandry, aquaculture, medical sterilization, and daily disinfectant.


Polyhexamethylene Biguanide HCL can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.


Polyhexamethylene Biguanide HCL is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.
Polyhexamethylene Biguanide HCL can be widely used in textile, animal husbandry, aquaculture, medical sterilization, and daily disinfectant.


Polyhexamethylene Biguanide HCL can be widely applied in the fields of daily chemical industry, water treatment, textile, papermaking, petroleum, agriculture, husbandry, health care etc.
Polyhexamethylene Biguanide HCL is often used as sanitary wet wipe bactericides, fruit, vegetable and aquatic product disinfectants, sewage treatment flocculation disinfectants etc.


Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene Biguanide HCL is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene Biguanide HCL is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene Biguanide HCL is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene Biguanide HCL is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene Biguanide HCL is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene Biguanide HCL is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene Biguanide HCL is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene Biguanide HCL is used as a disinfectant and antiseptic.


Polyhexamethylene Biguanide HCL is used as fungicides, bactericides mainly used in swimming pools, universal cleaning agents and disinfectants.
Polyhexamethylene Biguanide HCL is used as a disinfectant and antiseptic.
Polyhexamethylene Biguanide HCL is used as fungicides, bactericides mainly used in swimming pools, universal cleaning agents and disinfectants.


Polyhexamethylene Biguanide HCL can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant ,etc.
Polyhexamethylene Biguanide HCL is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.


Polyhexamethylene Biguanide HCL can be used directly after dilution with purified water or with other additive agent compound.
Since Polyhexamethylene Biguanide HCL in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.


As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene Biguanide HCL is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene Biguanide HCL can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant ,etc.


Polyhexamethylene Biguanide HCL is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.
Polyhexamethylene Biguanide HCL is used as a sanitizer or preservative to kill bacteria.


Polyhexamethylene Biguanide HCL restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast etc.
As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and more.


Polyhexamethylene Biguanide HCL is also widely used in evironmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene Biguanide HCL is used as a preservative in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.


Polyhexamethylene Biguanide HCL is used in cosmetics, the preservation of fruit and vegetables.
Polyhexamethylene Biguanide HCL is also used to preserve wet wipes; to control odor in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, farm equipment, animal drinking water, and hard surfaces for food handling institutions and hospitals; and to deodorize vacuums and toilets.


Polyhexamethylene Biguanide HCL can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant,etc.
Polyhexamethylene Biguanide HCL is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.


Polyhexamethylene Biguanide HCL is a synthetic polymer that is used in a variety of consumer and industrial products, including wet wipes.
Polyhexamethylene Biguanide HCL can be used directly after dilution with purified water or with other additive agent compound.
Since Polyhexamethylene Biguanide HCL in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.


Polyhexamethylene Biguanide HCL can be used directly after dilution with purified water or with other additive agent compound.
Since Polyhexamethylene Biguanide HCL in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.


Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene Biguanide HCL is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene Biguanide HCL is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene Biguanide HCL is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


Polyhexamethylene Biguanide HCL is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene Biguanide HCL is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene Biguanide HCL is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
As a medicinal product, Polyhexamethylene Biguanide HCL is used for disinfection of contact lenses, eye drops, and surgical procedures.


Due to the strong tolerance of the eyes to Polyhexamethylene Biguanide HCL.
Polyhexamethylene Biguanide HCL can be used as a drug for the treatment of Acanthopanaxa Miba keratitis and the prevention and treatment of other eye diseases.


At the same time, Polyhexamethylene Biguanide HCL is also widely used in cosmetics, personal care products, textiles, food industries, etc.
Polyhexamethylene Biguanide HCL is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.


Polyhexamethylene Biguanide HCL is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene Biguanide HCL is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene Biguanide HCL is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene Biguanide HCL is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


Polyhexamethylene Biguanide HCL is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene Biguanide HCL is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools.


Polyhexamethylene Biguanide HCL possesses marked characteristics of cationic polyelectrolyte.
There are also unique determination methods to Polyhexamethylene Biguanide HCL using its ion association with organic anions and polyanion.
As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.


As a medicinal product, Polyhexamethylene Biguanide HCL is used for disinfection of contact lenses, eye drops, and surgical procedures.
Due to the strong tolerance of the eyes to Polyhexamethylene Biguanide HCL.
Polyhexamethylene Biguanide HCL can be used as a drug for the treatment of Acanthopanaxa Miba keratitis and the prevention and treatment of other eye diseases.


As a sanitizer, Polyhexamethylene Biguanide HCL is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Another good application of Polyhexamethylene Biguanide HCL is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.
Polyhexamethylene Biguanide HCL is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.


As a preservative, Polyhexamethylene Biguanide HCL is utilized in chemical products like cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and so on.
Polyhexamethylene Biguanide HCL is applied as a sanitizer or preservative to kill bacteria.


At the same time, Polyhexamethylene Biguanide HCL is also widely used in cosmetics, personal care products, textiles, food industries, etc.
Polyhexamethylene Biguanide HCL is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene Biguanide HCL is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


As a preservative, Polyhexamethylene Biguanide HCL is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene Biguanide HCL restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast, and so on.
Polyhexamethylene Biguanide HCL is also commonly applied in eviromental disinfection area, such as in hospitals, schools, hotels, and a lot of other public sites.


Polyhexamethylene Biguanide HCL is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene Biguanide HCL is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools.


Polyhexamethylene Biguanide HCL possesses marked characteristics of cationic polyelectrolyte.
There are also unique determination methods to Polyhexamethylene Biguanide HCL using its ion association with organic anions and polyanion.


As a sanitizer, Polyhexamethylene Biguanide HCL is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Another good application of Polyhexamethylene Biguanide HCL is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.
Polyhexamethylene Biguanide HCL is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.


As a preservative, Polyhexamethylene Biguanide HCL is utilized in chemical products like cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and so on.
Polyhexamethylene Biguanide HCL is applied as a sanitizer or preservative to kill bacteria.


Polyhexamethylene Biguanide HCL restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast, and so on.
Polyhexamethylene Biguanide HCL is also commonly applied in eviromental disinfection area, such as in hospitals, schools, hotels, and a lot of other public sites.


Polyhexamethylene Biguanide HCL is often used as sanitary wet wipe bactericides, fruit, vegetable and aquatic product disinfectants, sewage treatment flocculation disinfectants etc.



PERFORMANCE FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL is recognized as the safest and the most efficient broad-spectrum antibacterial agent in the 21st century.
Polyhexamethylene Biguanide HCL is colorless and tasteless, low bacterial inhibition concentration, broad spectrum, low toxicity.
Polyhexamethylene Biguanide HCL can form a layer of cations on the surface of article, which can inhibit bacteria for a long time.
Polyhexamethylene Biguanide HCL also has no bacteria drug resistance.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene Biguanide HCL is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.

Polyhexamethylene Biguanide HCL is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene Biguanide HCL's special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene Biguanide HCL is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene Biguanide HCL is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene Biguanide HCL is non-toxic to human cells.



SPECIAL APPLICATIONS OF POLYHEXAMETHYLENE BIGUANIDE HCL:
1. Paper making industry:
In the process of papermaking and cardboard production, because Polyhexamethylene Biguanide HCL is cationic polymer electrolyte, it can be used as an auxiliary agent to accelerate pulp dehydration and mineral filler precipitation, so as to strengthen and improve papermaking process.
In addition, Polyhexamethylene Biguanide HCL can also stabilize the dispersion of paraffin and increase the size stability of paper.
The hydrophobicity of paper and hardboard paper increases by 40-50%.

The activity also reduces some problems related to the accumulation of pulp in papermaking machinery, and Polyhexamethylene Biguanide HCL can produce antibacterial paper for manufacturing health products (to replace the silver containing kursin paper).
At the same time, Polyhexamethylene Biguanide HCL also improves the physical properties of the paper: water absorption, strength after water, air permeability.


2. Agricultural application:
As Polyhexamethylene Biguanide HCL has the function of disease resistance and protection to plants, can effectively kill harmful bacteria, and is harmless to ecology, it is an environmental protection product, which makes the product completely applicable to all growth stages of various agricultural products: Treat seeds, bulbs or tubular seeds with 0.1-1% aqueous solution of Polyhexamethylene Biguanide HCL.
When the symptoms of vegetable diseases appear, spray with 0.01-0.1% Polyhexamethylene Biguanide HCL aqueous solution of the product (if necessary, add appropriate polyelectrolyte, such as polyacrylic acid).

In order to reduce the loss of storage in winter, 0.2% Polyhexamethylene Biguanide HCL aqueous solution of this product can be used to wash or spray vegetables and fruits.
In addition, Polyhexamethylene Biguanide HCL can overcome the damage of excessive herbicides to plants and prevent infection in the soil.

As a pesticide, the efficacy of Polyhexamethylene Biguanide HCL is ten times higher than that of Benazolin, chlorothalonil and sodium disulfonate.
Therefore, to achieve the same effect, the use amount of Polyhexamethylene Biguanide HCL 20% liquid is 10-30 times less.
Moreover, Polyhexamethylene Biguanide HCL is safe, non-toxic and non irritating, especially harmless to people and animals.


3. Oil exploitation:
In oil exploitation, a large number of bacteria, such as sulfate reducing bacteria, not only engulf the oil, but also degrade the polymer used (ordinary polymer with low molecular weight), reducing the efficiency of polymer flooding and increasing the cost.



BACTERICIDAL MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Bacteria quickly suffocate to death after using Polyhexamethylene Biguanide HCL.
At the same time, because this product is a polymer structure, which can improve the effective activity of guanidine group, the bactericidal effect of Polyhexamethylene Biguanide HCL is much higher than other guanidine compounds (such as chlorhexidine).
Due to the special bactericidal mechanism of this product, all kinds of bacteria will not be resistant to Polyhexamethylene Biguanide HCL, which has been confirmed by the experiments of foreign authoritative testing institutions.



FEATURES AND ADVANTAGES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
1. Long-acting nature:
After the solution of Polyhexamethylene Biguanide HCL is dried, a polymer thin layer of disinfectant is formed on the surface of the object, which can keep the state of the object after sterilization and prevent the secondary pollution of the object.
Generally, the surfaces treated with aqueous solution of Polyhexamethylene Biguanide HCL will remain sterile for up to three months.


2. Innocuity
As Polyhexamethylene Biguanide HCL is a high polymer, it is not easy to be absorbed by animal tissues, greatly reducing the toxicity, so that it has no effect on cells of higher organisms.
In addition, the experiment proves that Polyhexamethylene Biguanide HCL can be naturally degraded and will not cause pollution to the environment.
The conclusion is that "2% of Polyhexamethylene Biguanide HCL belongs to the actual non-toxic grade".


3. No irritation to skin:
The experimental study of Polyhexamethylene Biguanide HCL on skin was carried out with rabbits.
Conclusion: 2% of Polyhexamethylene Biguanide HCL has no skin irritation when the skin irritation response integral value is 0. (judgment standard: the lower the integral value, the lower the stimulation.)



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene Biguanide HCL is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.

Polyhexamethylene Biguanide HCL is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene Biguanide HCL's special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene Biguanide HCL is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene Biguanide HCL is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene Biguanide HCL is non-toxic to human cells.



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
*Broad spectrum kills and inhibits various types of microbial.
Polyhexamethylene Biguanide HCL is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexamethylene Biguanide HCL can be used as a disinfectant for almost all kinds of bacteria.

*Excellent stability:
Polyhexamethylene Biguanide HCL is still kept active after being heated at 280℃ for 15 min.
Polyhexamethylene Biguanide HCL is non-corrosive to metals.
Polyhexamethylene Biguanide HCL is non-corrosive to copper, stainless steel, carbon steel, and other metals.



STERILIZATION MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HCL:
1. The guanidine group in Polyhexamethylene Biguanide HCL performs a high activity and the polymer itself is cationic.
Since bacteria and viruses are usually anionic, they are easy to be absorbed by Polyhexamethylene Biguanide HCL and could not divide and reproduce, and finally turn inactive.

2. Polyhexamethylene Biguanide HCL collapses the cell membrane structure and forms transmembrane stomata.
Ultimately, Polyhexamethylene Biguanide HCL causes cell membrane rupture, disrupts the energy metabolism of the organism, and disables bacteria and viruses.

3. Polyhexamethylene Biguanide HCL forms a film that closes off the breathing passages of microorganisms, causing them to suffocate and die.
The sterilization mechanism is independent of the form and type of microorganisms.
Even if the microorganisms mutate, the mutation will not affect their efficacy.
Microorganisms do not produce resistance to Polyhexamethylene Biguanide HCL.



STORAGE OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL should be sealed and shaded to be stored in a dry, cool, well ventilated place.



PERFORMANCE FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL is recognized as the safest and the most efficient broad-spectrum antibacterial agent in the 21st century.
Polyhexamethylene Biguanide HCL is colorless and tasteless, low bacterial inhibition concentration, broad spectrum, low toxicity.
Polyhexamethylene Biguanide HCL can form a layer of cations on the surface of article, which can inhibit bacteria for a long time.
Polyhexamethylene Biguanide HCL also has no bacteria drug resistance.



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
*Broad spectrum kills and inhibits various types of microbial.
Polyhexamethylene Biguanide HCL is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexamethylene Biguanide HCL can be used as a disinfectant for almost all kinds of bacteria.

*Excellent stability:
Polyhexamethylene Biguanide HCL is still kept active after being heated at 280℃ for 15 min.
Polyhexamethylene Biguanide HCL is non-corrosive to metals.
Polyhexamethylene Biguanide HCL is non-corrosive to copper, stainless steel, carbon steel, and other metals.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene Biguanide HCL is a water solution that can be used as a broad-spectrum and high-efficiency disinfectant.

Polyhexamethylene Biguanide HCL is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene Biguanide HCL's special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene Biguanide HCL disinfectant is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene Biguanide HCL is non-corrosive to skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene Biguanide HCL is non-toxic to human cells.

Skin irritancy test shows that Polyhexamethylene Biguanide HCL is non-irritant to animal and human skin.
Polyhexamethylene Biguanide HCL can be widely used in textile, animal husbandry, aquiculture, medical sterilization, and daily disinfectant.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene Biguanide HCL is a water solution that can be used as a broad-spectrum and high-efficiency disinfectant.

Polyhexamethylene Biguanide HCL is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene Biguanide HCL's special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene Biguanide HCL disinfectant is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene Biguanide HCL is non-corrosive to skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene Biguanide HCL is non-toxic to human cells.

Skin irritancy test shows that Polyhexamethylene Biguanide HCL is non-irritant to animal and human skin.
Polyhexamethylene Biguanide HCL can be widely used in textile, animal husbandry, aquiculture, medical sterilization, and daily disinfectant.



SYNTHESIS OF POLYHEXAMETHYLENE BIGUANIDE HCL ANTIMICROBIAL:
*Adopt the melt polycondensation method.
Put the appropriate amount of guanidine hydrochloride and 1, 6-hexane-diamine in the polymerization kettle, stir, and raise the temperature.
After the reactants are completely melted, continue to raise the temperature, constant temperature reaction for about 2h.

And then raise the temperature to a predetermined temperature for the reaction.
After the reaction is finished, stop stirring, and pass nitrogen gas into the kettle.
Open the discharge port at the same time.

Let the product flow into the pre-prepared container.
Let Polyhexamethylene Biguanide HCL cool down and solidify, then crush it for use.
By following the above procedure, theoretically, a bulk polymer can be produced.

But in practice, due to the difference in the reactivity of the functional groups, will produce an insoluble cross-linked structure, cross-linked polymers are insoluble, and not conducive to melt processing, but as long as the appropriate reaction conditions can be controlled to obtain linear high molecular weight products.



STERILIZATION MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HCL:
1. The guanidine group in Polyhexamethylene Biguanide HCL performs a high activity and the polymer itself is cationic.
Since bacteria and viruses are usually anionic, they are easy to be absorbed by Polyhexamethylene Biguanide HCL and could not divide and reproduce, and finally turn inactive.

2. Polyhexamethylene Biguanide HCL collapses the cell membrane structure and forms transmembrane stomata.
Ultimately, Polyhexamethylene Biguanide HCL causes cell membrane rupture, disrupts the energy metabolism of the organism, and disables bacteria and viruses.

3. Polyhexamethylene Biguanide HCL forms a film that closes off the breathing passages of microorganisms, causing them to suffocate and die.
The sterilization mechanism is independent of the form and type of microorganisms.
Even if the microorganisms mutate, the mutation will not affect their efficacy.
Microorganisms do not produce resistance to Polyhexamethylene Biguanide HCL.



STORAGE OF POLYHEXAMETHYLENE BIGUANIDE HCL:
Polyhexamethylene Biguanide HCL should be sealed and shaded to be stored in a dry, cool, well ventilated place.



SYNTHESIS OF POLYHEXAMETHYLENE BIGUANIDE HCL ANTIMICROBIAL:
*Adopt the melt polycondensation method.
Put the appropriate amount of guanidine hydrochloride and 1, 6-hexane-diamine in the polymerization kettle, stir, and raise the temperature.
After the reactants are completely melted, continue to raise the temperature, constant temperature reaction for about 2h.

And then raise the temperature to a predetermined temperature for the reaction.
After the reaction is finished, stop stirring, and pass nitrogen gas into the kettle.
Open the discharge port at the same time.

Let the product flow into the pre-prepared container.
Let Polyhexamethylene Biguanide HCL cool down and solidify, then crush it for use.
By following the above procedure, theoretically, a bulk polymer can be produced.

But in practice, due to the difference in the reactivity of the functional groups, will produce an insoluble cross-linked structure, cross-linked polymers are insoluble, and not conducive to melt processing, but as long as the appropriate reaction conditions can be controlled to obtain linear high molecular weight products.



PHYSICAL and CHEMICAL PROPERTIES of POLYHEXAMETHYLENE BIGUANIDE HCL:
CAS: 32289-58-0 Poly(hexamethylenebiguanide) Hcl
Appearance: slightly yellow to colorless & clear
Content (wt%): 20
Water (wt%): 80max.
Total metal (ppm): 100max
Ordor: no ordor. PH (20% water): 3.0-5.5
Boling point(°C): 102-103
Specific gravity @25°C (g/cm3):1.03-1.05
Solubility in water (20°C): very good
Appearance: Colorless or pale-yellow transparent liquid
Boiling point(℃): 102
Content (%): 19.0-21.0
Relative density(g/ml,25℃): 1.04
pH: 4.0-6.0
Name: Polyhexamethylene biguanide hydrochloride; PHMB
CAS No.: 32289-58-0
Formula: (C8H17N5)n•xHCl
Molecular Weight: ≥1,600~2,600

CAS No.: 32289-58-0
Molecular Formula: (C8H18N5Cl)n n=12-16
Appearance: White powder, colorless translucent crystals, colorless liquid
Purity: 95%, 98%, ≥98%, 20%, 25%, 50%
Density (20℃): 1.039~1.046g/cm3
pH value (20℃): 4.0~6.0
Absorbance (237nm): ≥400
Absorbance (237nm/222nm): 1.2~1.6
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)
CAS 32289-58-0
Poly(hexamethylenebiguanide) Hcl
Content (wt%): 20
Water (wt%): 80 max.
Total metal (ppm): 100 max.
Odor: No odor

Boiling point (°C): 102-103
Specific gravity @25°C (g/cm3): 1.03-1.05
Solubility in water (20°C): Very good
HS Code: 29121900
Color of Liquid: Clear to Slight Haze
Water Solubility: Miscible
Application: Biocides, Water Treatment, Disinfectant
Appearance: Colorless or light-yellow solid
Active ingredient: ≥99%
Water soluble: 100% soluble
Odor: Light ammonia smell
Moisture content: ≤0.5%
Water insoluble matter: ≤0.1%
PH in 1% aqueous solution: >4
Ash: 0.05%
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)

CAS No.: 32289-58-0
Molecular Formula: (C8H18N5Cl)n n=12-16
Appearance: White powder, colorless translucent crystals, colorless liquid
Purity: 95%, 98%, ≥98%, 20%, 25%, 50%
Density (20℃): 1.039~1.046g/cm3
pH value (20℃): 4.0~6.0
Absorbance (237nm): ≥400
Absorbance (237nm/222nm): 1.2~1.6
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)
CAS 32289-58-0
Poly(hexamethylenebiguanide) Hcl
Content (wt%): 20
Water (wt%): 80 max.
Total metal (ppm): 100 max.
Odor: No odor

Boiling point (°C): 102-103
Specific gravity @25°C (g/cm3): 1.03-1.05
Solubility in water (20°C): Very good
HS Code: 29121900
Color of Liquid: Clear to Slight Haze
Water Solubility: Miscible
Application: Biocides, Water Treatment, Disinfectant
Appearance: Colorless or light-yellow solid
Active ingredient: ≥99%
Water soluble: 100% soluble
Odor: Light ammonia smell
Moisture content: ≤0.5%
Water insoluble matter: ≤0.1%
PH in 1% aqueous solution: >4
Ash: 0.05%
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)

CAS: 32289-58-0 Poly(hexamethylenebiguanide) Hcl
Appearance: slightly yellow to colorless & clear
Content (wt%): 20
Water (wt%): 80max.
Total metal (ppm): 100max
Ordor: no ordor. PH (20% water): 3.0-5.5
Boling point(°C): 102-103
Specific gravity @25°C (g/cm3):1.03-1.05
Solubility in water (20°C): very good
Appearance: Colorless or pale-yellow transparent liquid
Boiling point(℃): 102
Content (%): 19.0-21.0
Relative density(g/ml,25℃): 1.04
pH: 4.0-6.0
Name: Polyhexamethylene biguanide hydrochloride; PHMB
CAS No.: 32289-58-0
Formula: (C8H17N5)n•xHCl
Molecular Weight: ≥1,600~2,600



FIRST AID MEASURES of POLYHEXAMETHYLENE BIGUANIDE HCL:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POLYHEXAMETHYLENE BIGUANIDE HCL:
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of POLYHEXAMETHYLENE BIGUANIDE HCL:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media.
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYHEXAMETHYLENE BIGUANIDE HCL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection
Recommended Filter type: Filter type P1
-Control of environmental exposure
Do not let product enter drains.



HANDLING and STORAGE of POLYHEXAMETHYLENE BIGUANIDE HCL:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of POLYHEXAMETHYLENE BIGUANIDE HCL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available

POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE
Polyhexamethylene biguanide hydrochloride is a polymer applied as a disinfectant and anti-septic.
Polyhexamethylene biguanide hydrochloride is a colorless, tasteless, non-toxic side effects, no corrosion, no bleaching to all kinds of surface treatment.
Polyhexamethylene biguanide hydrochloride is available also as a solid.


CAS Number: 32289-58-0; 27083-27-8
EC Number: 1308068-626-2
Chemical Name:Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride
Molecular Formula: (C8H17N5)n


Polyhexamethylene biguanide hydrochloride possesses marked characteristics of cationic polyelectrolyte.
There are also unique determination methods to Polyhexamethylene biguanide hydrochloride using its ion association with organic anions and polyanion.
The solution of Polyhexamethylene biguanide hydrochloride is an important ingredient in some pharmaceutical or veterinary formulations.


Polyhexamethylene biguanide hydrochloride is a colorless, tasteless, non-toxic side effects, no corrosion, no bleaching to all kinds of surface treatment.
Polyhexamethylene biguanide hydrochloride is safe to use, no side effects, no irritation to skin, mucous membrane and eyes.
Polyhexamethylene biguanide hydrochloride has good biodegradability and will not cause environmental pollution.


Polyhexamethylene biguanide hydrochloride should be stored in a tightly sealed container in a cool, dry place away from sources of heat or ignition.
Performance data shows that Polyhexamethylene biguanide hydrochloride conforms to technical grade standards and has no significant environmental impact if handled according to guidelines.


Polyhexamethylene biguanide hydrochloride is an environmental-friendly Cationic Polymer.
Polyhexamethylene biguanide hydrochloride is water soluble and the aqueous solution is colorless and odorless, broad-spectrum, high-efficiency,low toxicity, good stability, non-flammable and non-explosive.


Normally Polyhexamethylene biguanide hydrochloride is non-corrosive to stainless steel, stainless copper, carbon steel, wood, plastic, etc.
Polyhexamethylene biguanide hydrochloride is a high molecular polymer, which is not easily absorbed by tissues, has no corrosive effect, has good stability and is easy to rinse, good biocompatibility.


Polyhexamethylene biguanide hydrochloride is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria.
The virus is adsorbed, thereby inhibiting the division ability of bacteria and viruses, making them lose their reproductive ability, and the film formed by the polymer blocks the respiratory channels of the microorganisms, causing the microorganisms to die quickly.


Polyhexamethylene biguanide hydrochloride, also known as PHMB, polyhexanide or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride renders it of potential interest in the field of supramolecular chemistry.


Polyhexamethylene biguanide hydrochloride is available also as a solid.
Polyhexamethylene biguanide hydrochloride is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.


Polyhexamethylene biguanide hydrochloride is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene biguanide hydrochloride's special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.


Polyhexamethylene biguanide hydrochloride is a cationic broad-spectrum antimicrobial agent, achieves bactericidal purpose by inhibiting cell membrane activity.
As a cell membrane active antimicrobial agent, Polyhexamethylene biguanide hydrochloride inhibits bacterial activity better than that of fungi.


Antimicrobial mechanism is roughly as follows: Polyhexamethylene biguanide hydrochloride is a polymerized cationic compound, which is easily adsorbed by various types of bacteria that are usually negatively charged, thus inhibiting the division function of the bacteria and making the bacteria lose the ability to reproduce.


Polyhexamethylene biguanide hydrochloride, also known as PHMB, polyhexanide or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride renders it of potential interest in the field of supramolecular chemistry.



USES and APPLICATIONS of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Polyhexamethylene biguanide hydrochloride can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eels, Aeromonas hydrophilic, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.


Polyhexamethylene biguanide hydrochloride is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceutical, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, sanitary pads, clothes, etc.
Polyhexamethylene biguanide hydrochloride is widely used in sterilization, disinfection and algaecide of skin, mucous membrane, fruit, air, drinking water, swimming pool, general object surface, clothing, aquaculture, animal husbandry and other industries


In the field of agriculture, Polyhexamethylene biguanide hydrochloride has a good prevention and treatment effect on plant seed treatment and bacterial diseases and insect pests of crops.
In the field of sewage treatment, Polyhexamethylene biguanide hydrochloride is able to kill bacteria and remove floccules.


Polyhexamethylene biguanide hydrochloride has high efficiency and broad spectrum to kill and inhibit all kinds of microorganisms, can effectively kill; Staphylococcus, Escherichia coli, dysentery, Candida albicans and other kinds of bacterial viruses, bacteria do not produce resistance.
Polyhexamethylene biguanide hydrochloride can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant ,etc.


Polyhexamethylene biguanide hydrochloride is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.
Polyhexamethylene biguanide hydrochloride can be used directly after dilution with purified water or with other additive agent compound.


Since Polyhexamethylene biguanide hydrochloride in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.
Polyhexamethylene biguanide hydrochloride restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast, and so on.


Guanidine group in this product has strong activity, making the polymer positive, so Polyhexamethylene biguanide hydrochloride is easy to be adsorbed by various bacteria and viruses that are usually negative, thus resisting the division function of bacteria and viruses, making the bacteria and viruses lose the reproductive ability.


In addition, the thin film formed by using Polyhexamethylene biguanide hydrochloride blocks the breathing channel of microorganisms, making microorganisms suffocate and die quickly.
Polyhexamethylene biguanide hydrochloride is applied as a sanitizer or preservative to kill bacteria.


As a preservative, Polyhexamethylene biguanide hydrochloride is utilized in chemical products like cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and so on.
Polyhexamethylene biguanide hydrochloride is also commonly applied in eviromental disinfection area, such as in hospitals, schools, hotels, and a lot of other public sites.


Some products containing Polyhexamethylene biguanide hydrochloride are applied for inter-operative irrigation, both before and after surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, scopy, first aid, surface disinfection, and linen disinfection.


Polyhexamethylene biguanide hydrochlorideeye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Another good application of Polyhexamethylene biguanide hydrochloride is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.


Polyhexamethylene biguanide hydrochloride is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
With a purity of 98%, Polyhexamethylene biguanide hydrochloride is commonly utilized in the healthcare and personal care industries.


Polyhexamethylene biguanide hydrochloride can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.


Polyhexamethylene biguanide hydrochloride is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.
Polyhexamethylene biguanide hydrochloride can be widely used in textile, animal husbandry, aquaculture, medical sterilization, and daily disinfectant.


Polyhexamethylene biguanide hydrochloride is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools.
Polyhexamethylene biguanide hydrochloride is used in the stabilization of fabric linings in shoes.


Biguanide solution is used in cleaning contact lenses.
Polyhexamethylene biguanide hydrochloride is a highly effective antimicrobial agent used in various applications such as disinfectants, sanitizers, and preservatives.


Polyhexamethylene biguanide hydrochloride is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene biguanide hydrochloride is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


As a preservative, Polyhexamethylene biguanide hydrochloride is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene biguanide hydrochloride is widely used in environmental disinfection including hospitals, schools, hotels, and public places.


Polyhexamethylene biguanide hydrochloride is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene biguanide hydrochloride is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene biguanide hydrochloride shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Polyhexamethylene biguanide hydrochloride is widely used in textile printing and dyeing, animal husbandry, aquaculture, medical sterilization and daily disinfection.


Polyhexamethylene biguanide hydrochloride is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools.
In dermatological use, Polyhexamethylene biguanide hydrochloride is also called polihexanide.


Polyhexamethylene biguanide hydrochloride is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


Polyhexamethylene biguanide hydrochloride is widely used in textile printing and dyeing, animal husbandry, aquaculture, medical sterilization and daily disinfection.
Polyhexamethylene biguanide hydrochloride is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools.


In dermatological use, Polyhexamethylene biguanide hydrochloride is also called polihexanide.
Polyhexamethylene biguanide hydrochloride is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


Polyhexamethylene biguanide hydrochloride shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Polyhexamethylene biguanide hydrochloride is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.


Polyhexamethylene biguanide hydrochloride is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
The Polyhexamethylene biguanide hydrochloride is used in the majority of formulations.
Polyhexamethylene biguanide hydrochloride is available also as a solid.


Polyhexamethylene biguanide hydrochloride can be widely applied in the fields of daily chemical industry, water treatment, textile, papermaking, petroleum, agriculture, husbandry, health care etc.
Polyhexamethylene biguanide hydrochloride is often used as sanitary wet wipe bactericides, fruit, vegetable and aquatic product disinfectants, sewage treatment flocculation disinfectants etc.


Polyhexamethylene biguanide hydrochloride is used as a disinfectant and antiseptic.
Polyhexamethylene biguanide hydrochloride is an antimicrobial agent active against both Gram-positive and Gram-negative bacteria.
Polyhexamethylene biguanide hydrochloride is used in antiseptic, disinfectant and cosmetics.


As a medicinal product, Polyhexamethylene biguanide hydrochloride is used for disinfection of contact lenses, eye drops, and surgical procedures.
Due to the strong tolerance of the eyes to Polyhexamethylene biguanide hydrochloride.
Polyhexamethylene biguanide hydrochloride can be used as a drug for the treatment of Acanthopanaxa Miba keratitis and the prevention and treatment of other eye diseases.


At the same time, Polyhexamethylene biguanide hydrochloride is also widely used in cosmetics, personal care products, textiles, food industries, etc.
Polyhexamethylene biguanide hydrochloride, 98% Cas 32289-58-0 - used as fungicides, bactericides mainly used in swimming pools, universal cleaning agents and disinfectants.


Polyhexamethylene biguanide hydrochloride shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Polyhexamethylene biguanide hydrochloride is a polymer used as a disinfectant and antiseptic.


In dermatological use, it is spelled polihexanide (INN) and sold under the names Lavasept, Serasept, Prontosan, and Omnicide.
Polyhexamethylene biguanide hydrochloride has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Aspergillus brasiliensis, enterococci, and Klebsiella pneumoniae.


Products containing Polyhexamethylene biguanide hydrochloride are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.


Polyhexamethylene biguanide hydrochloride eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Polyhexamethylene biguanide hydrochloride is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.


Polyhexamethylene biguanide hydrochloride is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Polyhexamethylene biguanide hydrochloride is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
The Polyhexamethylene biguanide hydrochloride is used in the majority of formulations.



PERFORMANCE CHARACTERISTICS OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
1. Polyhexamethylene biguanide hydrochloride is soluble in water, alcohol, efficient broad-spectrum killing and inhibiting all kinds of microorganisms
2. The action time of Polyhexamethylene biguanide hydrochloride is relatively long and bacteria do not produce drug resistance
3. Moreover, it will take action very fast and Polyhexamethylene biguanide hydrochloride is non-toxic to human body and higher animals under the use concentration
4. Polyhexamethylene biguanide hydrochloride's solution is colorless and odorless, no irritation to skin and mucous membrane
5. Polyhexamethylene biguanide hydrochloride is totally environment friendly, degradable, no damage and corrosion to the treated surface



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
1. Polyhexamethylene biguanide hydrochloride has the ability to inhibit Gram-positive bacteria, Gram-negative bacteria, fungi (many kinds of ringworm and mold) and yeast.
2. Polyhexamethylene biguanide hydrochloride has rapid inhibitory effect on E. coli, Staphylococcus aureus and Candida albicans.
3. Polyhexamethylene biguanide hydrochloride : LD50>5000mg/kg, HPMB is skin friendly, human and environment friendly.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Polyhexamethylene biguanide hydrochloride is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride is a water solution that can be used as a broad-spectrum and high-efficiency disinfectant.
Polyhexamethylene biguanide hydrochloride is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.

Because of Polyhexamethylene biguanide hydrochloride's special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.
Polyhexamethylene biguanide hydrochloride disinfectant is a high molecular polymer, which is easy to be washed away.

Polyhexamethylene biguanide hydrochloride is non-corrosive to skin, and can not be easily absorbed by human organs.
Polyhexamethylene biguanide hydrochloride is non-irritant to animal and human skin.
Polyhexamethylene biguanide hydrochloride can be widely used in textile, animal husbandry, aquiculture, medical sterilization, and daily disinfectant.



PERFORMANCE FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Polyhexamethylene biguanide hydrochloride is recognized as the safest and the most efficient broad-spectrum antibacterial agent in the 21st century.
Polyhexamethylene biguanide hydrochloride is colorless and tasteless, low bacterial inhibition concentration, broad spectrum, low toxicity.
Polyhexamethylene biguanide hydrochloride can form a layer of cations on the surface of article, which can inhibit bacteria for a long time.
Polyhexamethylene biguanide hydrochloride also has no bacteria drug resistance.



POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE IS USED DISINFECTANT DETERGENT FOR FRUITS AND VEGETABLES:
After a lot of screening and comparison, the main active ingredients and auxiliary components of disinfectant detergents for fruits and vegetables have been fully studied.
On this basis, Polyhexamethylene biguanide hydrochloride disinfectant was selected.

Polyhexamethylene biguanide hydrochloride is the main component of the fruit and vegetable disinfectant detergent.
Polyhexamethylene biguanide hydrochloride has the advantages of reliable sterilization effect, environmental protection, good stability, and use.
And Polyhexamethylene biguanide hydrochloride can be used in high dilution, is economic and cost-effective, and conducive to the promotion of use.

In addition, Polyhexamethylene biguanide hydrochloride and chlorhexidine acetate as the main components of poly hexamethylene biguanide hydrochloride compound disinfectant.
Polyhexamethylene biguanide hydrochloride also has a good bactericidal effect on the natural bacteria on the surface of fruits and vegetables.

Polyhexamethylene biguanide hydrochloride's average logarithmic value of killing natural bacteria on the surface of cucumber, apple, grape, and strawberry all reached above 2.08.



POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE İS USED ANTIMICROBIAL FINISHING AGENT FOR FABRICS:
Polyhexamethylene biguanide hydrochloride antimicrobial with dip-rolling, impregnation method, or spray method to treat cotton and its blended fabrics after dyeing or printing.
Polyhexamethylene biguanide hydrochloride can effectively inhibit the growth of bacteria.
Polyhexamethylene biguanide hydrochloride's antibacterial properties remain effective after 10~100 washes at 50℃.

Polyhexamethylene biguanide hydrochloride antimicrobial does not affect the main properties of textiles.
Polyhexamethylene biguanide hydrochloride is suitable for use on most cotton fiber products.
Polyhexamethylene biguanide hydrochloride disinfectant is a cationic oligomer.

Polyhexamethylene biguanide hydrochloride's distribution is said to be 2 to 40 biguanide units.
Each biguanide unit has 2 cationic groups.
The high molecular weight polyhexamethylene biguanide hydrochloride can form multiple adsorption points with the fiber surface, and the binding strength is high.



POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE IS USED IN CONTACT LENS CARE SOLUTION AND FEMALE LOTION:
At present, Polyhexamethylene biguanide hydrochloride and PAPB are the main active ingredients in contact lens care solutions.
They can recognize the phospholipid receptors on the surface of pathogenic microorganisms.
Thus, they can selectively destroy the cell membrane of pathogenic microorganisms and kill the pathogens.
BIGUANIDE antiseptic is less irritating and more effective and can be used as the main component of female lotion.



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Broad spectrum kills and inhibits various types of microbial:
Polyhexamethylene biguanide hydrochloride chemical is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexamethylene biguanide hydrochloride can be used as a disinfectant for almost all kinds of bacteria.

-Excellent stability
Polyhexamethylene biguanide hydrochloride still keeps active after being heated at 280℃ for 15 min.

-Non-corrosive to metals
Polyhexamethylene biguanide hydrochloride biocide is non-corrosive to copper, stainless steel, carbon steel, and other metals.



STERILIZATION MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
1. The guanidine group in Polyhexamethylene biguanide hydrochloride performs a high activity and the polymer itself is cationic.
Since bacteria and viruses are usually anionic, they are easy to be absorbed by Polyhexamethylene biguanide hydrochloride and could not divide and reproduce, and finally turn inactive.

2. Polyhexamethylene biguanide hydrochloride collapses the cell membrane structure and forms transmembrane stomata.
Ultimately, Polyhexamethylene biguanide hydrochloride causes cell membrane rupture, disrupts the energy metabolism of the organism, and disables the bacteria and virus.

3. Polyhexamethylene biguanide hydrochloride forms a film that closes off the breathing passages of microorganisms, causing them to suffocate and die.
The sterilization mechanism is independent of the form and type of microorganisms.
Even if the microorganisms mutate, the mutation will not affect their efficacy.
Microorganisms do not produce resistance to Polyhexamethylene biguanide hydrochloride.



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Broad spectrum kills and inhibits various types of microbial.
Polyhexamethylene biguanide hydrochloride is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexamethylene biguanide hydrochloride can be used as a disinfectant for almost all kinds of bacteria.

Polyhexamethylene biguanide hydrochloride has an excellent stability.
Polyhexamethylene biguanide hydrochloride is still kept active after being heated at 280℃ for 15 min.
Polyhexamethylene biguanide hydrochloride is non-corrosive to metals.
Polyhexamethylene biguanide hydrochloride is non-corrosive to copper, stainless steel, carbon steel, and other metals.



PACKING AND STORAGE OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Store Polyhexamethylene biguanide hydrochloride in a cool, dry, well-ventilated warehouse.
Keep away from Polyhexamethylene biguanide hydrochloride fire and heat sources.
Protect Polyhexamethylene biguanide hydrochloride from direct sunlight.
Polyhexamethylene biguanide hydrochloride should be stored separately from oxidizers, and flammable and combustible materials.



DOSAGE OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Polyhexamethylene biguanide hydrochloride is usually formulated with other water treatment chemicals.
The exact formula of Polyhexamethylene biguanide hydrochloride depends on water and equipment conditions.
The recommended dosage of Polyhexamethylene biguanide hydrochloride is 100~500 mg/L when used as a separate disinfectant.
The dosage of Polyhexamethylene biguanide hydrochloride should be determined by the exact process and method if applied in textile and printing, livestock-raising, and aquaculture.



SYNTHESIS OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE ANTIMICROBIAL:
Adopt the melt polycondensation method.
Put the appropriate amount of guanidine hydrochloride and 1, 6-hexane-diamine in the polymerization kettle, stir, and raise the temperature.
After the reactants are completely melted, continue to raise the temperature, constant temperature reaction for about 2h.
And then raise the temperature to a predetermined temperature for the reaction.

After the reaction is finished, stop stirring, and pass nitrogen gas into the kettle.
Open the discharge port at the same time. Let the product flow into the pre-prepared container.
Let it cool down and solidify, then crush it for use.
By following the above procedure, theoretically, a bulk polymer can be produced.

But in practice, due to the difference in the reactivity of the functional groups, will produce an insoluble cross-linked structure, cross-linked polymers are insoluble, and not conducive to melt processing, but as long as the appropriate reaction conditions can be controlled to obtain linear high molecular weight products.



PHYSICAL and CHEMICAL PROPERTIES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
Appearance: Colorless or light-yellow solid
Active ingredient: ≥99%
Water soluble: 100% soluble
Odor: Light ammonia smell
Moisture content: ≤0.5%
Water insoluble matter: ≤0.1%
PH in 1% aqueous solution: >4
Ash: 0.05%
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)
CAS: 32289-58-0 Poly(hexamethylenebiguanide) Hcl
Appearance: slightly yellow to colorless & clear
Content (wt%): 20
Water (wt%): 80max.
Total metal (ppm): 100max
Ordor: no ordor. PH (20% water): 3.0-5.5
Boling point(°C): 102-103
Specific gravity @25°C (g/cm3):1.03-1.05
Solubility in water (20°C): very good
Appearance: Colorless or pale-yellow transparent liquid
Boiling point(℃): 102
Content (%): 19.0-21.0
Relative density(g/ml,25℃): 1.04
pH: 4.0-6.0
Name: Polyhexamethylene biguanide hydrochloride; PHMB
CAS No.: 32289-58-0
Formula: (C8H17N5)n•xHCl
Molecular Weight: ≥1,600~2,600



FIRST AID MEASURES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media.
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection
Recommended Filter type: Filter type P1
-Control of environmental exposure
Do not let product enter drains.



HANDLING and STORAGE of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available



SYNONYMS:
Polyhexamethylene biguanide
Polyhexamethylene guanide
Poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) Hydrochloride
Poly(hexamethylenebiguanide)
Polihexanide
Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride
biguanide phmb
polyhexamethylene biguanidine
polihexanide
polyhexanide hydrochloride.
Poly(hexamethylenebiguanide) hydrochloride
Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride
PHMB(Poly Hexa Methylene Biguanide)
Polyhexanide hydrochloride
Polyhexamethylene biguanide hydrochloride
1-(diaminomethylidene)-2-hexylguanidine hydrochloride
PHMB; Polyhexamethylene biguanide
Poly(hexamethylene) biguanide hydrochloride
Polyhexamethylene biguanide hydrochloride
Poly(iminoimidocarbonyl)iminohexamethylene hydrochloride
N,N'''-1,6-Hexanediylbis(N'-cyanoguanidine) hexamethylenediamine polymer hydrochloride



POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB)

Polyhexamethylene biguanide hydrochloride (PHMB), also known simply as Polyhexanide, is a chemical compound belonging to the class of biguanides.
Polyhexamethylene biguanide hydrochloride (PHMB) is widely used as an antimicrobial agent and disinfectant due to its broad-spectrum activity against various microorganisms, including bacteria, viruses, fungi, and some protozoa.

CAS Number: 32289-58-0
EC Number: 608-723-9

Synonyms: Polyhexanide, Polyhexamethylene biguanide, PHMB, Polyhexamethylene biguanidine, Polyhexamethylene biguanidine hydrochloride, Polyaminopropyl biguanide, Polyhexamethylene guanide, Polyaminopropyl biguanidine hydrochloride, Polyaminopropyl biguanide HCl, Polyaminopropyl biguanidine dihydrochloride, Polyaminopropyl biguanidine, Polyhexanidine, Polyaminopropyl biguanidine HCl, Polyhexamethylene guanidine, Polyaminopropyl biguanide hydrochloride, Polyhexamethylene guanidine hydrochloride, Polyhexamethylene dihydrochloride, Polyhexamethylene guanidine dihydrochloride, Polyaminopropyl biguanide dihydrochloride, Polyhexamethylene biguanide hydrochloride, Polyhexamethylene guanidine dihydrochloride, Polyhexanidine hydrochloride, Polyaminopropyl biguanide dihydrochloride, Polyaminopropyl biguanide hydrochloride, Polyaminopropyl biguanidine dihydrochloride, Polyaminopropyl biguanidine HCl, Polyaminopropyl biguanidine, Polyaminopropyl biguanidine hydrochloride, Polyaminopropyl biguanidine hydrochloride, Polyhexanidine hydrochloride, Polyaminopropyl biguanidine hydrochloride, Polyaminopropyl biguanidine



APPLICATIONS


Polyhexamethylene biguanide hydrochloride (PHMB) is commonly used as a disinfectant in healthcare settings.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied for cleaning and disinfecting medical equipment and surfaces.
Polyhexamethylene biguanide hydrochloride (PHMB) is effective against a broad spectrum of microorganisms, including bacteria, viruses, fungi, and some protozoa.

Polyhexamethylene biguanide hydrochloride (PHMB) finds extensive use in hospitals, clinics, and other healthcare facilities to prevent infections.
Polyhexamethylene biguanide hydrochloride (PHMB) is particularly valuable in wound care for preventing and treating infections in open wounds.

Polyhexamethylene biguanide hydrochloride (PHMB) is incorporated into wound dressings and gels to promote wound healing while minimizing infection risk.
Polyhexamethylene biguanide hydrochloride (PHMB) is utilized in contact lens solutions for disinfecting and cleaning contact lenses.
Polyhexamethylene biguanide hydrochloride (PHMB) is found in various personal care products such as hand sanitizers, mouthwashes, and skincare formulations.

Polyhexamethylene biguanide hydrochloride (PHMB)is effective in preventing infections and controlling microbial growth in both clinical and personal care settings.
Polyhexamethylene biguanide hydrochloride (PHMB) is employed in veterinary medicine for disinfecting animal housing, equipment, and surgical instruments.
Polyhexamethylene biguanide hydrochloride (PHMB) is used topically in animals to treat skin infections and wounds.
Polyhexamethylene biguanide hydrochloride (PHMB) finds applications in agriculture for disinfecting greenhouse surfaces, irrigation systems, and agricultural equipment.

Polyhexamethylene biguanide hydrochloride (PHMB) is utilized in aquaculture to control bacterial and fungal infections in fish and shellfish.
Polyhexamethylene biguanide hydrochloride (PHMB) is found in household disinfectants and cleaning products for its antimicrobial properties.

Polyhexamethylene biguanide hydrochloride (PHMB) is applied in swimming pools and spas to control bacterial and algal growth.
Polyhexamethylene biguanide hydrochloride (PHMB) is used in water treatment systems for disinfecting drinking water and wastewater.

Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the preservation of industrial products such as paints, coatings, and adhesives.
Polyhexamethylene biguanide hydrochloride (PHMB) is incorporated into antifungal coatings for building materials and textiles.

Polyhexamethylene biguanide hydrochloride (PHMB) finds applications in the preservation of cosmetics and personal care products.
Polyhexamethylene biguanide hydrochloride (PHMB) is used in the preservation of food and beverages to extend shelf life and prevent spoilage.

Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the production of antimicrobial textiles for various industries.
Polyhexamethylene biguanide hydrochloride (PHMB) is utilized in wound irrigation solutions for emergency medical care.
Polyhexamethylene biguanide hydrochloride (PHMB) is used in the treatment of burns and scalds to prevent infection and promote healing.

Polyhexamethylene biguanide hydrochloride (PHMB) is applied in the treatment of respiratory infections and other infectious diseases.
Polyhexamethylene biguanide hydrochloride (PHMB) plays a crucial role in maintaining cleanliness, preventing infections, and promoting public health across various sectors.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in the production of wound debridement solutions for removing necrotic tissue and debris.
Polyhexamethylene biguanide hydrochloride (PHMB) finds applications in the treatment of ear infections and otitis externa in both humans and animals.
Polyhexamethylene biguanide hydrochloride (PHMB) is incorporated into wound irrigation solutions for cleansing and disinfecting wounds during medical procedures.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in dental care products such as mouthwashes and dental rinses to reduce oral bacteria and prevent gum diseases.
Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the treatment of fungal infections such as athlete's foot and nail fungus.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in the production of antimicrobial coatings for medical devices, implants, and surgical instruments.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied in the manufacture of disinfectant wipes and towelettes for convenient surface disinfection.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in the treatment of skin conditions such as acne and folliculitis to reduce bacterial colonization.
Polyhexamethylene biguanide hydrochloride (PHMB) is incorporated into ophthalmic solutions to prevent contamination and microbial growth.
Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the treatment of animal wounds and skin infections in veterinary medicine.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in the preservation of industrial water systems to control microbial growth and biofilm formation.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied in the treatment of burns and scalds to prevent infection and promote wound healing.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in the preservation of cosmetics and toiletry products to prevent microbial contamination.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied in the preservation of industrial fluids such as cutting oils, lubricants, and hydraulic fluids.
Polyhexamethylene biguanide hydrochloride (PHMB) is utilized in the treatment of fungal nail infections (onychomycosis) to inhibit fungal growth.

Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the production of wound irrigation solutions for use in emergency medical care.
Polyhexamethylene biguanide hydrochloride (PHMB) is used in the treatment of eye infections such as conjunctivitis and keratitis.

Polyhexamethylene biguanide hydrochloride (PHMB) is applied in the preservation of household products such as cleaning solutions, detergents, and fabric softeners.
Polyhexamethylene biguanide hydrochloride (PHMB) is used in the production of antifungal coatings for building materials and textiles.

Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the treatment of surgical site infections to prevent post-operative complications.
PHMB is used in the preservation of water-based paints, coatings, and adhesives to prevent microbial contamination.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied in the treatment of respiratory infections such as sinusitis and bronchitis.

Polyhexamethylene biguanide hydrochloride (PHMB) is employed in the treatment of swimming pool and spa water to control bacterial and algal growth.
Polyhexamethylene biguanide hydrochloride (PHMB) is utilized in various industrial applications where effective disinfection and microbial control are required.
Polyhexamethylene biguanide hydrochloride (PHMB) serves as a versatile antimicrobial agent with applications spanning across healthcare, personal care, veterinary medicine, agriculture, and industrial sectors.



DESCRIPTION


Polyhexamethylene biguanide hydrochloride (PHMB), also known simply as Polyhexanide, is a chemical compound belonging to the class of biguanides.
Polyhexamethylene biguanide hydrochloride (PHMB) is widely used as an antimicrobial agent and disinfectant due to its broad-spectrum activity against various microorganisms, including bacteria, viruses, fungi, and some protozoa.

Polyhexamethylene biguanide hydrochloride (PHMB) is a cationic polymer, meaning it carries a positive charge, which enables it to interact with and disrupt the cell membranes of microorganisms, leading to their destruction.
This mechanism of action makes PHMB effective in preventing and treating infections in various settings, including healthcare, personal care, veterinary medicine, and industrial applications.

In healthcare, PHMB is used for disinfecting medical equipment, surfaces, and wounds.
Polyhexamethylene biguanide hydrochloride (PHMB) is commonly found in wound dressings, antiseptic solutions, and topical formulations for wound care.
Polyhexamethylene biguanide hydrochloride (PHMB) is also utilized in personal care products such as hand sanitizers, mouthwashes, and skincare products for its antimicrobial properties.

Furthermore, PHMB is used in veterinary medicine for disinfecting animal housing, equipment, and surgical instruments.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied topically to treat skin infections and wounds in animals.
In addition, Polyhexamethylene biguanide hydrochloride (PHMB) finds applications in agriculture for disinfecting irrigation systems, animal drinking water, and agricultural equipment.

Polyhexamethylene biguanide hydrochloride (PHMB) is a versatile and effective antimicrobial agent with diverse applications across various industries.
Its ability to kill a wide range of microorganisms makes it an essential tool in infection control, hygiene practices, and public health efforts.

Polyhexamethylene biguanide hydrochloride (PHMB) is a synthetic cationic polymer.
Polyhexamethylene biguanide hydrochloride (PHMB) is a clear, colorless liquid or solid at room temperature.
Polyhexamethylene biguanide hydrochloride (PHMB) has no distinct odor, making it suitable for use in various formulations.

Polyhexamethylene biguanide hydrochloride (PHMB) is highly soluble in water and many organic solvents.
Polyhexamethylene biguanide hydrochloride (PHMB) exhibits strong antimicrobial properties against a wide range of microorganisms.

Polyhexamethylene biguanide hydrochloride (PHMB) works by disrupting the cell membranes of bacteria, viruses, fungi, and some protozoa.
Polyhexamethylene biguanide hydrochloride (PHMB) is known for its broad-spectrum activity and long-lasting effectiveness.

Polyhexamethylene biguanide hydrochloride (PHMB) is commonly used in healthcare settings for disinfecting surfaces and medical equipment.
Polyhexamethylene biguanide hydrochloride (PHMB) is widely used in wound care products for preventing and treating infections.
Polyhexamethylene biguanide hydrochloride (PHMB) is incorporated into wound dressings, gels, and irrigation solutions.

Polyhexamethylene biguanide hydrochloride (PHMB) is utilized in personal care products such as hand sanitizers and mouthwashes.
Polyhexamethylene biguanide hydrochloride (PHMB) is effective in controlling microbial growth in swimming pools and spa water.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in agriculture for disinfecting irrigation systems and animal housing.
Polyhexamethylene biguanide hydrochloride (PHMB) is applied in veterinary medicine for treating skin infections and wounds in animals.

Polyhexamethylene biguanide hydrochloride (PHMB) is used in industrial applications for preserving paints, coatings, and adhesives.
Polyhexamethylene biguanide hydrochloride (PHMB) is compatible with a wide range of materials.
Polyhexamethylene biguanide hydrochloride (PHMB) is stable under normal storage conditions but may degrade under extreme pH or temperature.

Polyhexamethylene biguanide hydrochloride (PHMB) is considered biodegradable under aerobic conditions.
Polyhexamethylene biguanide hydrochloride (PHMB) is non-corrosive to most metals and materials.
Polyhexamethylene biguanide hydrochloride (PHMB) is non-flammable and poses low acute toxicity to humans and animals.

PHMB is commonly used in combination with other antimicrobial agents for synergistic effects.
Polyhexamethylene biguanide hydrochloride (PHMB) has been extensively researched for its safety and efficacy.

Polyhexamethylene biguanide hydrochloride (PHMB) is regulated by various regulatory agencies for its use in different applications.
This versatile compound plays a crucial role in infection control and public health efforts.
Polyhexamethylene biguanide hydrochloride (PHMB) is a valuable antimicrobial agent with diverse applications across multiple industries.



PROPERTIES


Physical Properties:

Appearance: Clear, colorless liquid or solid.
Odor: Odorless or may have a faint characteristic odor.
Melting Point: Typically ranges from 145°C to 155°C.
Boiling Point: Decomposes before reaching a specific boiling point.
Density: Approximately 1.1 to 1.2 g/cm³.
Solubility: Highly soluble in water and many organic solvents.
pH: Typically acidic in aqueous solutions, with a pH range of 4 to 6.
Vapor Pressure: Low vapor pressure at room temperature.
Viscosity: Varies depending on concentration and temperature.
Molecular Weight: Approximately 500 to 1000 g/mol.
Hygroscopicity: May absorb moisture from the atmosphere.


Chemical Properties:

Chemical Formula: (C8H17N5)n • HCl, where n represents the number of repeating units.
Molecular Structure: Contains repeating units of hexamethylene biguanide with a hydrochloride salt group.
Ionic Character: Forms positively charged biguanide groups in aqueous solutions.
Stability: Stable under normal storage conditions but may degrade upon exposure to extreme pH, temperature, or light.
Reactivity: Generally compatible with most common materials but may react with strong oxidizing agents or reducing agents.
Solubility: Highly soluble in water but may have limited solubility in non-polar solvents.
Flammability: Non-flammable under normal conditions.
Corrosivity: Non-corrosive to most metals and materials.
Toxicity: Low acute toxicity but should be handled with care to avoid ingestion or prolonged skin contact.
Biodegradability: Considered biodegradable under aerobic conditions, but persistence in the environment may vary.
Photostability: May degrade upon exposure to ultraviolet (UV) radiation.
Compatibility: Generally compatible with other chemicals used in formulations, but compatibility testing is recommended.
Chelating Properties: May exhibit chelating properties with certain metal ions.
Oxidation State: Contains nitrogen atoms in both the +1 and +4 oxidation states within the biguanide structure.
Hydrolysis: Stable under neutral and acidic conditions but may undergo hydrolysis under alkaline conditions.



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
Assist with breathing if necessary. Provide oxygen if breathing is difficult.
Seek medical attention promptly. Transport the individual to a medical facility for further evaluation and treatment.


Skin Contact:

Immediately remove contaminated clothing and shoes.
Rinse the affected area thoroughly with plenty of water for at least 15 minutes.
Use soap or mild detergent to cleanse the skin thoroughly, ensuring that all traces of the chemical are removed.
If irritation persists or if skin damage is evident, seek medical attention promptly.
Cover the affected area with a clean, dry dressing to prevent further contamination and irritation.


Eye Contact:

Flush the eyes with gently flowing lukewarm water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing of the eyes.
Remove contact lenses, if present and easily removable, during the flushing process.
Seek immediate medical attention, and transport the individual to an eye care professional for further evaluation and treatment.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth with water and drink plenty of water to dilute any remaining chemical.
Seek immediate medical attention or contact a poison control center for further guidance.
Do not administer any oral fluids or medications unless directed by a healthcare professional.

Notes to Physician:

Provide the physician with information regarding the type and extent of exposure.
Monitor the individual for any signs or symptoms of systemic toxicity.
Treat symptoms accordingly based on the individual's condition and response to exposure.
Administer supportive care and appropriate medical interventions as necessary.


Protection of First Responders:

First responders should wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing.
Ensure adequate ventilation in the area of exposure to prevent the buildup of vapors or fumes.
Prevent further exposure to the chemical by following proper handling procedures and containment measures.


Environmental Precautions:

Prevent the chemical from entering waterways, sewers, or soil to avoid environmental contamination.
Contain and collect any spilled material using appropriate absorbents and containment measures.
Dispose of contaminated materials in accordance with local regulations and guidelines.


Fire and Explosion Hazards:

Polyhexamethylene biguanide hydrochloride (PHMB) is not flammable under normal conditions.
In case of fire involving other materials, use appropriate extinguishing agents such as water spray, foam, dry chemical, or carbon dioxide (CO2).


Accidental Release Measures:

Contain the spillage to prevent further spread of the chemical.
Absorb spilled material with inert absorbents such as sand, vermiculite, or commercial absorbent pads.
Collect spilled material in appropriate containers for disposal according to local regulations.


Handling and Storage:

Handle Polyhexamethylene biguanide hydrochloride (PHMB) with care to prevent spills and accidental exposure.
Store in a cool, dry, well-ventilated area away from incompatible materials.
Keep containers tightly closed when not in use to prevent contamination.
Follow proper handling procedures to minimize the risk of exposure.



HANDLING AND STORAGE


Handling Precautions:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles, and protective clothing, when handling PHMB.
Use respiratory protection if there is a risk of inhalation exposure, especially in poorly ventilated areas.
Avoid skin contact and eye exposure by wearing suitable protective gear.


Ventilation:
Work with PHMB in a well-ventilated area to minimize exposure to vapors or aerosols.
Use local exhaust ventilation or mechanical ventilation systems to control airborne concentrations of the chemical.
Ensure adequate airflow in confined spaces or areas with limited ventilation.


Handling Procedures:
Handle PHMB with caution to prevent spills and accidental exposure.
Use appropriate handling techniques, such as pouring slowly and avoiding splashing or aerosolization of the chemical.
Do not eat, drink, or smoke while handling PHMB to prevent ingestion or inhalation of the chemical.

Storage Compatibility:
Store PHMB away from incompatible materials such as strong acids, bases, oxidizing agents, and reducing agents.
Separate from food and feedstuffs to prevent contamination.
Store in a dedicated area with proper containment measures to prevent spills and leaks.

Container Handling:
Use containers made of compatible materials, such as high-density polyethylene (HDPE) or glass, for storing PHMB.
Ensure that containers are tightly closed and properly labeled with the chemical name, concentration, hazard symbols, and handling precautions.
Do not reuse empty containers unless properly cleaned and decontaminated.


Storage Conditions:

Temperature:
Store PHMB in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Avoid exposure to extreme temperatures, as it may affect the stability and efficacy of the chemical.

Humidity:
Keep containers tightly closed to prevent moisture ingress and potential degradation of PHMB.
Store in a humidity-controlled environment, if possible, to maintain product integrity.

Light Exposure:
Protect PHMB from prolonged exposure to ultraviolet (UV) radiation, as it may degrade the chemical over time.
Store in opaque or light-resistant containers to minimize light-induced degradation.

Accessibility:
Store containers of PHMB in a location easily accessible for handling and retrieval.
Keep storage areas organized and free from clutter to facilitate inventory management and emergency response.

Security Measures:
Restrict access to storage areas containing PHMB to authorized personnel only.
Implement security measures to prevent theft, vandalism, or unauthorized use of the chemical.

Emergency Preparedness:
Keep emergency spill control materials, such as absorbents, neutralizing agents, and personal protective equipment, readily available in the storage area.
Develop and implement an emergency response plan for handling spills, leaks, or accidental exposures to PHMB.

POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB)
Polyhexamethylene biguanide hydrochloride (PHMB) is a polymer used as a disinfectant and antiseptic.
In dermatological use, Polyhexamethylene biguanide hydrochloride (PHMB) is spelled polihexanide (INN) and sold under the names Lavasept, Tebasept, Prontosan.
Products containing Polyhexamethylene biguanide hydrochloride (PHMB) are used for inter-operative irrigation, pre- and post-surgery skin and mucous membrane disinfection, post-operative dressings, surgical and non-surgical wound dressings, surgical bath/hydrotherapy, chronic wounds like diabetic foot ulcer and burn wound management, routine antisepsis during minor incisions, catheterization, first aid, surface disinfection, and linen disinfection.

CAS: 32289-58-0
MF: C10H23N5
MW: 213.32312
EINECS: 1308068-626-2

Synonyms
PHMB(20%);Polyhexamethyl;PHMB;Biguanide PHMB;Polyhexamethylene biguanidine hydrochloride,~20% in water;PHMB 98%, 20% solution (Polyhexamethylene biguanide hydrochloride);20% solution;98% powder;32289-58-0;N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide;Poly (hexamethylene biguanide);SCHEMBL24018755;Polyhexamethylene Biguanidine HCl;SAGIGHPRUJPLKX-UHFFFAOYSA-N;BCP13780;AKOS015919499;N-(6-(3-Methylguanidino)hexyl)acetimidamide;N-[6-(N'-METHYLCARBAMIMIDAMIDO)HEXYL]ETHANIMIDAMIDE;1824322-57-7

Polyhexamethylene biguanide hydrochloride (PHMB) eye drops have been used as a treatment for eyes affected by Acanthamoeba keratitis.
Polyhexamethylene biguanide hydrochloride (PHMB) is sold as a swimming pool and spa disinfectant in place of chlorine or bromine based products under the name Baquacil.
Polyhexamethylene biguanide hydrochloride (PHMB) is also used as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.
Polyhexamethylene biguanide hydrochloride (PHMB) is also used to treat clothing (Purista), purportedly to prevent the development of unpleasant odors.
The Polyhexamethylene biguanide hydrochloride (PHMB) is used in the majority of formulations.
Polyhexamethylene biguanide hydrochloride (PHMB) is best known for its broad-spectrum antimicrobial and antifungal activity.
Polyhexamethylene biguanide hydrochloride (PHMB) is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu.
Polyhexamethylene biguanide hydrochloride (PHMB) is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.

Polyhexamethylene biguanidine, also known as Polyhexamethylene biguanide hydrochloride (PHMB), polyhexanide or polihexanide, is a highly water soluble and hydrolytically stable polymeric material.
The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride (PHMB) renders it of potential interest in the field of supramolecular chemistry.
Polyhexamethylene biguanide hydrochloride (PHMB) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.
Polyhexamethylene biguanide hydrochloride (PHMB) is available also as a solid.

Polyhexamethylene biguanide hydrochloride (PHMB) Chemical Properties
Storage temp.: Inert atmosphere,Room Temperature
Solubility: Water
Form: Solid
Color: White to off-white
InChI: InChI=1S/C10H23N5/c1-9(11)14-7-5-3-4-6-8-15-10(12)13-2/h3-8H2,1-2H3,(H2,11,14)(H3,12,13,15)
InChIKey: SAGIGHPRUJPLKX-UHFFFAOYSA-N
CAS DataBase Reference: 32289-58-0(CAS DataBase Reference)
EPA Substance Registry System: Polyhexamethylene biguanide hydrochloride (PHMB) (32289-58-0)

Polyhexamethylene biguanide hydrochloride (PHMB) is also used as a surface disinfectant and is alleged to be suitable for skin disinfection.
Polyhexamethylene biguanide hydrochloride (PHMB) has a slow effectand does not meet the practical requirementsfor prophylactic antiseptics in this respect.
Although Polyhexamethylene biguanide hydrochloride (PHMB) is somewhat less effective than benzalkonium chloride, it is sometimes used instead of benzalkonium because it is less foamproducing under use conditions.

Polyhexamethylene biguanide hydrochloride (PHMB) is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride (PHMB) is a water solution that can be used as a broad spectrum and high efficient disinfectant.
Polyhexamethylene biguanide hydrochloride (PHMB) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene biguanide hydrochloride (PHMB)'s special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Preparation
The preparation method of Polyhexamethylene biguanide hydrochloride (PHMB):By a certain proportion of 1; the own bisguanides of 6-and catalyst join in reaction vessel; under nitrogen protection, said mixture is heated to 80-200 DEGC and reacts, react 2-24 hour; reaction terminates; cooling blowing, obtains poly hexamethylene biguanide, poly hexamethylene biguanide aqueous acid is neutralized to pH value 5-9; and performing filtering so as to obtain a polyhexamethylene biguanidine salt.

Biological Activity
Polyhexamethylene biguanide hydrochloride (PHMB) is a cationic polymer with antimicrobial and antiviral properties.
Polyhexamethylene biguanide hydrochloride (PHMB) has been commonly accepted that the antimicrobial activity is due to the ability of PHMB to perforate the bacterial phospholipid membrane leading ultimately to its death.
POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl)V
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is best known for its broad-spectrum antimicrobial and antifungal activity.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions.


Cas Number:32289-58-0
EC Number: 1308068-626-2
Chemical Name:Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride
Chemical Formula: (C8H17N5)n•(HCl)x



SYNONYMS:
Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB(Poly Hexa Methylene Biguanide), Polyhexamethylene biguanidine Hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB (Poly Hexa Methylene Biguanide), Polyhexamethylene biguanidine Hydrochloride, Pure Polyhexamethylene biguanide Hydrochloride (PHMB) CAS 32289-58-0, Poly(hexamethylenebiguanide) Hcl, Poly(hexamethylenebiguanide)hydrochloride, Polyhexamethylene biguanide, Polyhexamethylene guanide, Poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) Hydrochloride, Poly(hexamethylenebiguanide), Polihexanide, Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB(Poly Hexa Methylene Biguanide), Polyhexanide hydrochloride, Polyhexamethylene biguanide hydrochloride, 1-(diaminomethylidene)-2-hexylguanidine hydrochloride, PHMB; Polyhexamethylene biguanide, Poly(hexamethylene) biguanide hydrochloride, Polyhexamethylene biguanide hydrochloride, Poly(iminoimidocarbonyl)iminohexamethylene hydrochloride, N,N'''-1,6-Hexanediylbis(N'-cyanoguanidine) hexamethylenediamine polymer hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB (Poly Hexa Methylene Biguanide), Polyhexamethylene biguanidine Hydrochloride, Pure Polyhexamethylene biguanide Hydrochloride (PHMB) CAS 32289-58-0, Poly(hexamethylenebiguanide) Hcl, Poly(hexamethylenebiguanide)hydrochloride, Polyhexamethylene biguanide, Polyhexamethylene guanide, Poly(iminoimidocarbonyl-iminoimidocarbonyl-iminohexamethylene) Hydrochloride, Poly(hexamethylenebiguanide), Polihexanide, Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl) hydrochloride, biguanide phmb, polyhexamethylene biguanidine, polihexanide, polyhexanide hydrochloride, Poly(hexamethylenebiguanide) hydrochloride, Poly(hexamethylenebicyanoguanide-hexamethylenediamine) hydrochloride, PHMB(Poly Hexa Methylene Biguanide), Polyhexanide hydrochloride, Polyhexamethylene biguanide hydrochloride, 1-(diaminomethylidene)-2-hexylguanidine hydrochloride, PHMB; Polyhexamethylene biguanide, Poly(hexamethylene) biguanide hydrochloride, Polyhexamethylene biguanide hydrochloride, Poly(iminoimidocarbonyl)iminohexamethylene hydrochloride, N,N'''-1,6-Hexanediylbis(N'-cyanoguanidine) hexamethylenediamine polymer hydrochloride



Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is an antimicrobial agent that kills or inhibits the growth of bacteria, fungi, and other microorganisms.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is best known for its broad-spectrum antimicrobial and antifungal activity.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a disinfectant and antiseptic.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also effective against a wide range of viruses, including influenza and hepatitis.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


The solution of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is an important ingredient in some pharmaceutical or veterinary formulations.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride (PHMB-HCl) renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is available also as 20% aqueous solution.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride (PHMB-HCl) renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is available also as 20% aqueous solution.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer applied as a disinfectant and antiseptic.
In dermatological use, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also called polihexanide.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) has been used in wet wipes for many years and is considered to be safe and effective.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride (PHMB-HCl) renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is available also as 20% aqueous solution.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer applied as a disinfectant and antiseptic.
In dermatological use, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also called polihexanide.


The presence of multiple hydrogen bond and chelation sites within Polyhexamethylene biguanide hydrochloride (PHMB-HCl) renders it of potential interest to those studying supramolecular chemical effects.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is available also as 20% aqueous solution.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is best known for its broad-spectrum antimicrobial and antifungal activity.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a disinfectant and antiseptic.


The bactericidal ability of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is better than other bactericides.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer applied as a disinfectant and antiseptic.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a colorless or light yellow transparent liquid, in which the guanidine group has high activity, which can make the polymer into a positive charge, and it is easily attacked by various negatively charged bacteria and bacteria.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is very effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


The solution of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is an important ingredient in some pharmaceutical or veterinary formulations.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) shows activity against both Gram-positive and Gram-negative bacteria and is widely used across several sectors, typically as the hydrochloride salt, in a variety of disinfectant solutions and antiseptics.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a highly water soluble and hydrolytically stable polymeric material.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer applied as a disinfectant and antiseptic.


In particular, Polyhexamethylene biguanide hydrochloride (PHMB-HCl)'s unique long-term antibacterial effect and the ability to prevent secondary infection are not achieved by other fungicides.



USES and APPLICATIONS of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as a sanitizer or preservative to kill bacteria.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast etc.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be widely used in textile, animal husbandry, aquaculture, medical sterilization, and daily disinfectant.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be widely applied in the fields of daily chemical industry, water treatment, textile, papermaking, petroleum, agriculture, husbandry, health care etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is often used as sanitary wet wipe bactericides, fruit, vegetable and aquatic product disinfectants, sewage treatment flocculation disinfectants etc.


As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and more.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be widely applied in the fields of daily chemical industry, water treatment, textile, papermaking, petroleum, agriculture, husbandry, health care etc.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can completely kill escherichia coli, staphylococcus aureus, candida Albicans, gonococcus, salmonella, pseudomonas aeruginosa, listeria, dysentery, aspergillus niger, brucella, vibrio parahaemolyticus, vibrio algolyticus, vibrio eelis, Aeromonas hydrophilus, sulfate-reducing bacteria, iron bacteria, and saprophytic bacteria.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is suitable to care solutions for contact lenses, cosmetics, medical, pharmaceuticals, skin, mucosa, vegetable, fruit, air, drinking water, swimming pool, paper making, tissue, anitary pads, clothes, etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be widely used in textile, animal husbandry, aquaculture, medical sterilization, and daily disinfectant.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also widely used in evironmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.


As a sanitizer, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as a preservative in cosmetics, personal care products, fabric softeners, contact lens solutions, hand washes, and more.
As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as a disinfectant and antiseptic.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as fungicides, bactericides mainly used in swimming pools, universal cleaning agents and disinfectants.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant,etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used directly after dilution with purified water or with other additive agent compound.
Since Polyhexamethylene biguanide hydrochloride (PHMB-HCl) in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.
As a sanitizer, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


As a medicinal product, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used for disinfection of contact lenses, eye drops, and surgical procedures.
Due to the strong tolerance of the eyes to Polyhexamethylene biguanide hydrochloride (PHMB-HCl).
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as a drug for the treatment of Acanthopanaxa Miba keratitis and the prevention and treatment of other eye diseases.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, the preservation of fruit and vegetables.
As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
At the same time, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also widely used in cosmetics, personal care products, textiles, food industries, etc.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used to preserve wet wipes; to control odor in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, farm equipment, animal drinking water, and hard surfaces for food handling institutions and hospitals; and to deodorize vacuums and toilets.


As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as a disinfectant and antiseptic.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as fungicides, bactericides mainly used in swimming pools, universal cleaning agents and disinfectants.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) possesses marked characteristics of cationic polyelectrolyte.
There are also unique determination methods to Polyhexamethylene biguanide hydrochloride (PHMB-HCl) using its ion association with organic anions and polyanion.


As a sanitizer, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Another good application of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant,etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a polymer used as a sanitizer or preservative to kill bacteria.


As a sanitizer, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast, and so on.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also commonly applied in eviromental disinfection area, such as in hospitals, schools, hotels, and a lot of other public sites.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a synthetic polymer that is used in a variety of consumer and industrial products, including wet wipes.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as disinfectant, antibacterial, bactericide, mildew-proof, algae-inhibitor, flocculant,etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in health care, chemicals, textiles, paper, wipes, livestock, aquaculture, fisheries, plastics, agriculture, water treatment and other fields.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used directly after dilution with purified water or with other additive agent compound.
Since Polyhexamethylene biguanide hydrochloride (PHMB-HCl) in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.


As a sanitizer, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used to preserve wet wipes; to control odour in textiles; to prevent microbial contamination in wound irrigation and sterile dressings; to disinfect medical/dental utensil and trays, to sterilize farm equipment, animal drinking water, and hard surfaces for food handling, to sterilize institutions such as hospitals and schools; and to deodorize vacuums machines and toilets.


Another good application of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is that it is widely used as a swimming-pool and spa water sanitizer instead of chlorine- or bromine-based commodities.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also utilized as an ingredient in some contact lens cleaning products, cosmetics, personal deodorants and some veterinary products.


As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is utilized in chemical products like cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and so on.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is applied as a sanitizer or preservative to kill bacteria.


As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is utilized in chemical products like cosmetics, personal care products, fabric softeners, contactlens solutions, hand washes, and so on.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is applied as a sanitizer or preservative to kill bacteria.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) restrains the gram-positive bacterium, gram-negative bacterium, fungus and yeast, and so on.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also commonly applied in eviromental disinfection area, such as in hospitals, schools, hotels, and a lot of other public sites.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is often used as sanitary wet wipe bactericides, fruit, vegetable and aquatic product disinfectants, sewage treatment flocculation disinfectants etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used directly after dilution with purified water or with other additive agent compound.


As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.


As a medicinal product, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used for disinfection of contact lenses, eye drops, and surgical procedures.
Due to the strong tolerance of the eyes to Polyhexamethylene biguanide hydrochloride (PHMB-HCl).
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as a drug for the treatment of Acanthopanaxa Miba keratitis and the prevention and treatment of other eye diseases.


At the same time, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also widely used in cosmetics, personal care products, textiles, food industries, etc.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used as an antimicrobial hand wash and sanitization and in air filtration treatment as an alternative to ozone.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is also used as an active ingredient for recreational water treatment, as a chlorine-free polymeric sanitizer, which is effective against a wide variety of microorganisms.
As a preservative, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is used in cosmetics, personal care products, fabric softeners, contact lens solutions and more.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used in environmental disinfection including hospitals, schools, hotels, and public places.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely utilized as a disinfectant in personal care commodities like cosmetics and toiletries and as a sanitizer in swimming pools.


Polyhexamethylene biguanide hydrochloride (PHMB-HCl) possesses marked characteristics of cationic polyelectrolyte.
There are also unique determination methods to Polyhexamethylene biguanide hydrochloride (PHMB-HCl) using its ion association with organic anions and polyanion.


Since Polyhexamethylene biguanide hydrochloride (PHMB-HCl) in different areas of application, the product dosage are quite different, it is recommended to use under the guidance of our professional and technical persons.



SPECIAL APPLICATIONS OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
1. Paper making industry:
In the process of papermaking and cardboard production, because Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is cationic polymer electrolyte, it can be used as an auxiliary agent to accelerate pulp dehydration and mineral filler precipitation, so as to strengthen and improve papermaking process.

In addition, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can also stabilize the dispersion of paraffin and increase the size stability of paper.
The hydrophobicity of paper and hardboard paper increases by 40-50%.

The activity also reduces some problems related to the accumulation of pulp in papermaking machinery, and Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can produce antibacterial paper for manufacturing health products (to replace the silver containing kursin paper).
At the same time, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) also improves the physical properties of the paper: water absorption, strength after water, air permeability.


2. Agricultural application:
As Polyhexamethylene biguanide hydrochloride (PHMB-HCl) has the function of disease resistance and protection to plants, can effectively kill harmful bacteria, and is harmless to ecology, it is an environmental protection product, which makes the product completely applicable to all growth stages of various agricultural products: Treat seeds, bulbs or tubular seeds with 0.1-1% aqueous solution of Polyhexamethylene biguanide hydrochloride (PHMB-HCl).

When the symptoms of vegetable diseases appear, spray with 0.01-0.1% Polyhexamethylene biguanide hydrochloride (PHMB-HCl) aqueous solution of the product (if necessary, add appropriate polyelectrolyte, such as polyacrylic acid).

In order to reduce the loss of storage in winter, 0.2% Polyhexamethylene biguanide hydrochloride (PHMB-HCl) aqueous solution of this product can be used to wash or spray vegetables and fruits.
In addition, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can overcome the damage of excessive herbicides to plants and prevent infection in the soil.

As a pesticide, the efficacy of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is ten times higher than that of Benazolin, chlorothalonil and sodium disulfonate.
Therefore, to achieve the same effect, the use amount of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) 20% liquid is 10-30 times less.
Moreover, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is safe, non-toxic and non irritating, especially harmless to people and animals.


3. Oil exploitation:
In oil exploitation, a large number of bacteria, such as sulfate reducing bacteria, not only engulf the oil, but also degrade the polymer used (ordinary polymer with low molecular weight), reducing the efficiency of polymer flooding and increasing the cost.



PERFORMANCE FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is recognized as the safest and the most efficient broad-spectrum antibacterial agent in the 21st century.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is colorless and tasteless, low bacterial inhibition concentration, broad spectrum, low toxicity.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can form a layer of cations on the surface of article, which can inhibit bacteria for a long time.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) also has no bacteria drug resistance.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene biguanide hydrochloride (PHMB-HCl)'s special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-toxic to human cells.



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
*Broad spectrum kills and inhibits various types of microbial.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as a disinfectant for almost all kinds of bacteria.

*Excellent stability:
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is still kept active after being heated at 280℃ for 15 min.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to metals.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to copper, stainless steel, carbon steel, and other metals.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a water solution that can be used as a broad-spectrum and high-efficiency disinfectant.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene biguanide hydrochloride (PHMB-HCl)'s special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) disinfectant is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-toxic to human cells.

Skin irritancy test shows that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-irritant to animal and human skin.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be widely used in textile, animal husbandry, aquiculture, medical sterilization, and daily disinfectant.



STERILIZATION MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
1. The guanidine group in Polyhexamethylene biguanide hydrochloride (PHMB-HCl) performs a high activity and the polymer itself is cationic.
Since bacteria and viruses are usually anionic, they are easy to be absorbed by Polyhexamethylene biguanide hydrochloride (PHMB-HCl) and could not divide and reproduce, and finally turn inactive.

2. Polyhexamethylene biguanide hydrochloride (PHMB-HCl) collapses the cell membrane structure and forms transmembrane stomata.
Ultimately, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) causes cell membrane rupture, disrupts the energy metabolism of the organism, and disables bacteria and viruses.

3. Polyhexamethylene biguanide hydrochloride (PHMB-HCl) forms a film that closes off the breathing passages of microorganisms, causing them to suffocate and die.
The sterilization mechanism is independent of the form and type of microorganisms.
Even if the microorganisms mutate, the mutation will not affect their efficacy.
Microorganisms do not produce resistance to Polyhexamethylene biguanide hydrochloride (PHMB-HCl).



STORAGE OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) should be sealed and shaded to be stored in a dry, cool, well ventilated place.



SYNTHESIS OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL) ANTIMICROBIAL:
*Adopt the melt polycondensation method.
Put the appropriate amount of guanidine hydrochloride and 1, 6-hexane-diamine in the polymerization kettle, stir, and raise the temperature.
After the reactants are completely melted, continue to raise the temperature, constant temperature reaction for about 2h.

And then raise the temperature to a predetermined temperature for the reaction.
After the reaction is finished, stop stirring, and pass nitrogen gas into the kettle.
Open the discharge port at the same time.

Let the product flow into the pre-prepared container.
Let Polyhexamethylene biguanide hydrochloride (PHMB-HCl) cool down and solidify, then crush it for use.
By following the above procedure, theoretically, a bulk polymer can be produced.

But in practice, due to the difference in the reactivity of the functional groups, will produce an insoluble cross-linked structure, cross-linked polymers are insoluble, and not conducive to melt processing, but as long as the appropriate reaction conditions can be controlled to obtain linear high molecular weight products.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a water solution that can be used as a broad-spectrum and high efficiency disinfectant.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene biguanide hydrochloride (PHMB-HCl)'s special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to the skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-toxic to human cells.



FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
*Broad spectrum kills and inhibits various types of microbial.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is odorless and can be easily dissolved in water to form a tasteless colorless transparent solution.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be used as a disinfectant for almost all kinds of bacteria.

*Excellent stability:
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is still kept active after being heated at 280℃ for 15 min.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to metals.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to copper, stainless steel, carbon steel, and other metals.



STERILIZATION MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
1. The guanidine group in Polyhexamethylene biguanide hydrochloride (PHMB-HCl) performs a high activity and the polymer itself is cationic.
Since bacteria and viruses are usually anionic, they are easy to be absorbed by Polyhexamethylene biguanide hydrochloride (PHMB-HCl) and could not divide and reproduce, and finally turn inactive.

2. Polyhexamethylene biguanide hydrochloride (PHMB-HCl) collapses the cell membrane structure and forms transmembrane stomata.
Ultimately, Polyhexamethylene biguanide hydrochloride (PHMB-HCl) causes cell membrane rupture, disrupts the energy metabolism of the organism, and disables bacteria and viruses.

3. Polyhexamethylene biguanide hydrochloride (PHMB-HCl) forms a film that closes off the breathing passages of microorganisms, causing them to suffocate and die.
The sterilization mechanism is independent of the form and type of microorganisms.
Even if the microorganisms mutate, the mutation will not affect their efficacy.
Microorganisms do not produce resistance to Polyhexamethylene biguanide hydrochloride (PHMB-HCl).



BACTERICIDAL MECHANISM OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
Bacteria quickly suffocate to death after using Polyhexamethylene biguanide hydrochloride (PHMB-HCl).
At the same time, because this product is a polymer structure, which can improve the effective activity of guanidine group, the bactericidal effect of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is much higher than other guanidine compounds (such as chlorhexidine).
Due to the special bactericidal mechanism of this product, all kinds of bacteria will not be resistant to Polyhexamethylene biguanide hydrochloride (PHMB-HCl), which has been confirmed by the experiments of foreign authoritative testing institutions.



FEATURES AND ADVANTAGES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
1. Long-acting nature:
After the solution of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is dried, a polymer thin layer of disinfectant is formed on the surface of the object, which can keep the state of the object after sterilization and prevent the secondary pollution of the object.
Generally, the surfaces treated with aqueous solution of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) will remain sterile for up to three months.


2. Innocuity
As Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a high polymer, it is not easy to be absorbed by animal tissues, greatly reducing the toxicity, so that it has no effect on cells of higher organisms.
In addition, the experiment proves that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be naturally degraded and will not cause pollution to the environment.
The conclusion is that "2% of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) belongs to the actual non-toxic grade".


3. No irritation to skin:
The experimental study of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) on skin was carried out with rabbits.
Conclusion: 2% of Polyhexamethylene biguanide hydrochloride (PHMB-HCl) has no skin irritation when the skin irritation response integral value is 0. (judgment standard: the lower the integral value, the lower the stimulation.)



STORAGE OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) should be sealed and shaded to be stored in a dry, cool, well ventilated place.



PERFORMANCE FEATURES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is recognized as the safest and the most efficient broad-spectrum antibacterial agent in the 21st century.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is colorless and tasteless, low bacterial inhibition concentration, broad spectrum, low toxicity.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can form a layer of cations on the surface of article, which can inhibit bacteria for a long time.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) also has no bacteria drug resistance.



PROPERTIES OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL):
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a new environment-friendly cationic water-soluble polymer.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is a water solution that can be used as a broad-spectrum and high-efficiency disinfectant.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is low toxic, steady, non-flammable, non-explosive, and basically non-corrosive to stainless steel, copper, carbon steel, wood, and plastic.
Because of Polyhexamethylene biguanide hydrochloride (PHMB-HCl)'s special bactericidal mechanisms, almost all kinds of bacteria shall be killed efficiently and will not develop resistance action.

Polyhexamethylene biguanide hydrochloride (PHMB-HCl) disinfectant is a high molecular polymer, which is easy to be washed away.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-corrosive to skin, and can not be easily absorbed by human organs.
Vitro studies show that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-toxic to human cells.

Skin irritancy test shows that Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is non-irritant to animal and human skin.
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) can be widely used in textile, animal husbandry, aquiculture, medical sterilization, and daily disinfectant.



SYNTHESIS OF POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCL) ANTIMICROBIAL:
*Adopt the melt polycondensation method.
Put the appropriate amount of guanidine hydrochloride and 1, 6-hexane-diamine in the polymerization kettle, stir, and raise the temperature.
After the reactants are completely melted, continue to raise the temperature, constant temperature reaction for about 2h.

And then raise the temperature to a predetermined temperature for the reaction.
After the reaction is finished, stop stirring, and pass nitrogen gas into the kettle.
Open the discharge port at the same time.

Let the product flow into the pre-prepared container.
Let Polyhexamethylene biguanide hydrochloride (PHMB-HCl) cool down and solidify, then crush it for use.
By following the above procedure, theoretically, a bulk polymer can be produced.

But in practice, due to the difference in the reactivity of the functional groups, will produce an insoluble cross-linked structure, cross-linked polymers are insoluble, and not conducive to melt processing, but as long as the appropriate reaction conditions can be controlled to obtain linear high molecular weight products.



PHYSICAL and CHEMICAL PROPERTIES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
CAS No.: 32289-58-0
Molecular Formula: (C8H18N5Cl)n n=12-16
Appearance: White powder, colorless translucent crystals, colorless liquid
Purity: 95%, 98%, ≥98%, 20%, 25%, 50%
Density (20℃): 1.039~1.046g/cm3
pH value (20℃): 4.0~6.0
Absorbance (237nm): ≥400
Absorbance (237nm/222nm): 1.2~1.6
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)
CAS 32289-58-0
Poly(hexamethylenebiguanide) Hcl
Content (wt%): 20
Water (wt%): 80 max.
Total metal (ppm): 100 max.
Odor: No odor

Boiling point (°C): 102-103
Specific gravity @25°C (g/cm3): 1.03-1.05
Solubility in water (20°C): Very good
HS Code: 29121900
Color of Liquid: Clear to Slight Haze
Water Solubility: Miscible
Application: Biocides, Water Treatment, Disinfectant
Appearance: Colorless or light-yellow solid
Active ingredient: ≥99%
Water soluble: 100% soluble
Odor: Light ammonia smell
Moisture content: ≤0.5%
Water insoluble matter: ≤0.1%
PH in 1% aqueous solution: >4
Ash: 0.05%
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)

CAS: 32289-58-0 Poly(hexamethylenebiguanide) Hcl
Appearance: slightly yellow to colorless & clear
Content (wt%): 20
Water (wt%): 80max.
Total metal (ppm): 100max
Ordor: no ordor. PH (20% water): 3.0-5.5
Boling point(°C): 102-103
Specific gravity @25°C (g/cm3):1.03-1.05
Solubility in water (20°C): very good
Appearance: Colorless or pale-yellow transparent liquid
Boiling point(℃): 102
Content (%): 19.0-21.0
Relative density(g/ml,25℃): 1.04
pH: 4.0-6.0
Name: Polyhexamethylene biguanide hydrochloride; PHMB
CAS No.: 32289-58-0
Formula: (C8H17N5)n•xHCl
Molecular Weight: ≥1,600~2,600

CAS: 32289-58-0 Poly(hexamethylenebiguanide) Hcl
Appearance: slightly yellow to colorless & clear
Content (wt%): 20
Water (wt%): 80max.
Total metal (ppm): 100max
Ordor: no ordor. PH (20% water): 3.0-5.5
Boling point(°C): 102-103
Specific gravity @25°C (g/cm3):1.03-1.05
Solubility in water (20°C): very good
Appearance: Colorless or pale-yellow transparent liquid
Boiling point(℃): 102
Content (%): 19.0-21.0
Relative density(g/ml,25℃): 1.04
pH: 4.0-6.0
Name: Polyhexamethylene biguanide hydrochloride; PHMB
CAS No.: 32289-58-0
Formula: (C8H17N5)n•xHCl
Molecular Weight: ≥1,600~2,600

CAS No.: 32289-58-0
Molecular Formula: (C8H18N5Cl)n n=12-16
Appearance: White powder, colorless translucent crystals, colorless liquid
Purity: 95%, 98%, ≥98%, 20%, 25%, 50%
Density (20℃): 1.039~1.046g/cm3
pH value (20℃): 4.0~6.0
Absorbance (237nm): ≥400
Absorbance (237nm/222nm): 1.2~1.6
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)
CAS 32289-58-0
Poly(hexamethylenebiguanide) Hcl
Content (wt%): 20
Water (wt%): 80 max.
Total metal (ppm): 100 max.
Odor: No odor

Boiling point (°C): 102-103
Specific gravity @25°C (g/cm3): 1.03-1.05
Solubility in water (20°C): Very good
HS Code: 29121900
Color of Liquid: Clear to Slight Haze
Water Solubility: Miscible
Application: Biocides, Water Treatment, Disinfectant
Appearance: Colorless or light-yellow solid
Active ingredient: ≥99%
Water soluble: 100% soluble
Odor: Light ammonia smell
Moisture content: ≤0.5%
Water insoluble matter: ≤0.1%
PH in 1% aqueous solution: >4
Ash: 0.05%
Active substance: Polyhexamethylene biguanide Hydrochloride (PHMB)



FIRST AID MEASURES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
-Environmental precautions
Do not let product enter drains.
-Methods and materials for containment and cleaning up
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media.
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Respiratory protection
Recommended Filter type: Filter type P1
-Control of environmental exposure
Do not let product enter drains.



HANDLING and STORAGE of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (PHMB-HCl):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available
-Incompatible materials:
No data available


POLYHEXAMETHYLENE BIGUANIDE HYDROCHLORIDE (POLYHEXANIDE)

Polyhexamethylene biguanide hydrochloride, commonly known as Polyhexanide, is a chemical compound used primarily as an antiseptic and disinfectant.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) belongs to the biguanide class of compounds and is known for its broad-spectrum antimicrobial properties.

CAS Number: 32289-58-0
EC Number: 251-899-3

Synonyms: PHMB, Polyhexamethylene guanide hydrochloride, PHMB hydrochloride, Polyaminopropyl biguanide hydrochloride, Polyhexamethylene biguanidine hydrochloride, Polyhexamethylene dihydrochloride, Polyhexamethylene guanidine hydrochloride, Polyhexanide hydrochloride, Polyaminopropyl biguanide HCl, Polyhexanidine hydrochloride, PHMB dihydrochloride, Polyhexanide dihydrochloride, Polyaminopropyl biguanide dihydrochloride, Polyhexamethylene guanidine hydrochloride, Polyaminopropyl biguanide hydrochloride, Polyhexamethylene guanidine dihydrochloride, Polyaminopropyl biguanide HCl, Polyhexamethylene guanidine dihydrochloride, Polyaminopropyl biguanide, Polyhexanidine, PHMB dihydrochloride, Polyhexanidine dihydrochloride, Polyaminopropyl biguanidine hydrochloride, Polyhexamethylene biguanide hydrochloride, Polyhexanidine hydrochloride, Polyaminopropyl biguanidine dihydrochloride, Polyhexamethylene guanidine, Polyaminopropyl biguanidine, Polyhexamethylene guanidine hydrochloride, Polyaminopropyl biguanidine HCl, Polyhexamethylene guanidine dihydrochloride



APPLICATIONS


Polyhexamethylene biguanide hydrochloride (Polyhexanide) is widely used as a disinfectant in healthcare settings.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is commonly applied to clean and disinfect medical equipment and surfaces.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in hospitals, clinics, and other healthcare facilities to prevent the spread of infections.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed for disinfecting medical devices such as surgical instruments, endoscopes, and catheters.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is effective against a broad spectrum of microorganisms, including bacteria, viruses, fungi, and some protozoa.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is utilized in wound care to prevent and treat infections in open wounds.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is incorporated into wound dressings and gels to promote healing and reduce the risk of infection.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in contact lens solutions to disinfect and clean contact lenses.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in personal care products such as hand sanitizers and mouthwashes for its antimicrobial properties.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is included in skincare formulations, including cleansers and moisturizers, to control bacteria and prevent skin infections.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in veterinary medicine for disinfecting animal housing, equipment, and surgical instruments.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied topically to treat skin infections in animals, including wounds and dermatitis.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in agriculture to disinfect greenhouse surfaces, irrigation systems, and agricultural equipment.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in aquaculture to control bacterial and fungal infections in fish and shellfish.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in household disinfectants and cleaning products for its antimicrobial properties.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is incorporated into fabric disinfectants and laundry additives to sanitize clothing and linens.
Polyhexanide is utilized in swimming pools and spas to control bacterial and algal growth.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in water treatment systems to disinfect drinking water and wastewater.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the preservation of industrial products, including paints, coatings, and adhesives.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the manufacture of antifungal coatings for building materials and textiles.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the preservation of cosmetics and personal care products to prevent microbial contamination.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the preservation of food and beverages to extend shelf life and prevent spoilage.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the production of antimicrobial textiles for healthcare, hospitality, and sportswear industries.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the treatment of swimming pool and spa water to control bacterial and algal growth.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is utilized in various industrial applications where effective disinfection and microbial control are required.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the preservation of ophthalmic solutions to prevent contamination and microbial growth.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the manufacture of wound irrigation solutions to cleanse and disinfect wounds during medical procedures.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the treatment of chronic wounds such as diabetic ulcers and pressure sores to prevent infection and promote healing.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in dental care products such as mouthwashes and dental rinses to reduce oral bacteria and prevent gingivitis.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is utilized in the treatment of fungal infections such as athlete's foot and nail fungus.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the production of antimicrobial coatings for medical devices, implants, and surgical instruments.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the manufacture of disinfectant wipes and towelettes for convenient surface disinfection.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the treatment of skin conditions such as acne and folliculitis to reduce bacterial colonization.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the preservation of pharmaceutical preparations such as eye drops, nasal sprays, and injectable medications.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the treatment of ear infections and otitis externa to control bacterial and fungal growth.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is utilized in the production of hand sanitizers and hand wipes for personal hygiene and infection control.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the treatment of animal wounds and skin infections in veterinary medicine.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the preservation of industrial water systems to control microbial growth and biofilm formation.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the treatment of burns and scalds to prevent infection and promote wound healing.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the preservation of cosmetic and toiletry products such as shampoos, creams, and lotions.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the treatment of bacterial infections such as cellulitis and impetigo.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is utilized in the production of wound irrigation solutions for use in emergency medical care.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the treatment of eye infections such as conjunctivitis and keratitis.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the preservation of water-based paints, coatings, and adhesives to prevent microbial contamination.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the treatment of surgical site infections to prevent post-operative complications.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the preservation of industrial fluids such as cutting oils, lubricants, and hydraulic fluids.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is utilized in the treatment of fungal nail infections (onychomycosis) to inhibit fungal growth.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is used in the production of wound debridement solutions for the removal of necrotic tissue and debris.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is employed in the treatment of respiratory infections such as sinusitis and bronchitis.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is applied in the preservation of household products such as cleaning solutions, detergents, and fabric softeners.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) remains effective even in the presence of organic matter and does not easily degrade.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is typically formulated as a solution or gel for ease of application.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is well-tolerated by the skin and mucous membranes when used as directed.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) has low toxicity and is considered safe for topical use in recommended concentrations.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) works by disrupting the cell membranes of microorganisms, leading to their destruction.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) penetrates microbial biofilms and inhibits the growth and reproduction of bacteria.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is non-corrosive and does not damage surfaces or medical equipment.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is compatible with a wide range of materials commonly used in healthcare settings.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is odorless and colorless, making it suitable for use in various formulations.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is often used in combination with other antimicrobial agents for synergistic effects.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is biocompatible and does not cause tissue irritation or sensitization when used appropriately.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is well-studied and has been extensively researched for its safety and efficacy.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is recommended for use in infection control protocols and wound management guidelines.

Healthcare professionals rely on Polyhexanide for its role in preventing healthcare-associated infections.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) plays a crucial role in maintaining a clean and safe environment in healthcare settings and in promoting wound healing and infection prevention.



DESCRIPTION


Polyhexamethylene biguanide hydrochloride, commonly known as Polyhexanide, is a chemical compound used primarily as an antiseptic and disinfectant.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) belongs to the biguanide class of compounds and is known for its broad-spectrum antimicrobial properties.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is often used in healthcare settings for disinfecting medical devices, surfaces, and wounds.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is effective against a wide range of microorganisms, including bacteria, viruses, fungi, and some protozoa.
In addition to its use in healthcare, Polyhexanide is also employed in various other applications, such as in contact lens solutions, personal care products, and wound care products.

The chemical structure of Polyhexanide consists of repeating hexamethylene biguanide units, with a hydrochloride salt group attached.
This structure allows it to disrupt the cell membranes of microorganisms, leading to their destruction.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is considered safe for use when applied topically or used as directed.
However, it's essential to follow recommended guidelines for dilution and application to minimize the risk of irritation or adverse effects.

Polyhexamethylene biguanide hydrochloride, commonly known as Polyhexanide, is a potent antimicrobial agent.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is widely used for its broad-spectrum disinfectant properties.

Polyhexanide exhibits strong activity against bacteria, viruses, fungi, and some protozoa.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is commonly employed in healthcare settings for disinfecting medical equipment, surfaces, and wounds.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is effective in preventing infections and controlling the spread of pathogens in clinical environments.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is particularly useful in wound care for its ability to prevent and treat infections in open wounds.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) is also utilized in contact lens solutions to disinfect and clean contact lenses.
In addition to its medical applications, Polyhexanide is used in personal care products for its antimicrobial properties.

Polyhexamethylene biguanide hydrochloride (Polyhexanide) can be found in products such as hand sanitizers, mouthwashes, and skincare formulations.
Polyhexamethylene biguanide hydrochloride (Polyhexanide) is known for its stability and long-lasting antimicrobial activity.




PROPERTIES


Physical Properties:

Appearance: Typically a clear, colorless liquid or solid.
Odor: Odorless or may have a faint characteristic odor.
Melting Point: Typically ranges from 145°C to 155°C.
Boiling Point: Decomposes before reaching a specific boiling point.
Density: Approximately 1.1 to 1.2 g/cm³.
Solubility: Soluble in water and many organic solvents.
pH: Typically acidic in aqueous solutions, with a pH range of 4 to 6.
Vapor Pressure: Low vapor pressure at room temperature.
Viscosity: Varies depending on concentration and temperature.
Molecular Weight: Approximately 500 to 1000 g/mol.
Hygroscopicity: May absorb moisture from the atmosphere.


Chemical Properties:

Chemical Formula: (C8H17N5)n • HCl, where n represents the number of repeating units.
Molecular Structure: Contains repeating units of hexamethylene biguanide with a hydrochloride salt group.
Ionic Character: Forms positively charged biguanide groups in aqueous solutions.
Stability: Stable under normal storage conditions but may degrade upon exposure to extreme pH, temperature, or light.
Reactivity: Generally compatible with most common materials but may react with strong oxidizing agents or reducing agents.
Solubility: Highly soluble in water but may have limited solubility in non-polar solvents.
Flammability: Non-flammable under normal conditions.
Corrosivity: Non-corrosive to most metals and materials.
Toxicity: Low acute toxicity but should be handled with care to avoid ingestion or prolonged skin contact.



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
Provide artificial respiration if breathing is difficult.
Seek medical attention if respiratory symptoms persist.


Skin Contact:

Immediately remove contaminated clothing and shoes.
Wash the affected area with plenty of water for at least 15 minutes.
Use soap or mild detergent to cleanse the skin thoroughly.
Seek medical attention if irritation, redness, or other symptoms develop.
If skin irritation persists, seek medical advice.


Eye Contact:

Flush the eyes with gently flowing lukewarm water for at least 15 minutes.
Remove contact lenses if present and easy to do so.
Seek immediate medical attention if irritation or redness persists.
Provide the eye doctor with information about the chemical involved.


Ingestion:

If swallowed, do not induce vomiting unless directed by medical personnel.
Rinse the mouth thoroughly with water.
Do not give anything by mouth to an unconscious person.
Seek immediate medical attention or contact a poison control center.


Notes to Physician:

Provide supportive care and symptomatic treatment as necessary.
In case of ingestion, consider the possibility of aspiration and monitor for respiratory distress.
Treat symptoms based on the individual's condition and response to exposure.
Provide appropriate medical interventions based on the route of exposure and severity of symptoms.


Protection of First Responders:

First responders should wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and protective clothing.
Ensure adequate ventilation in the area of exposure.
Prevent further exposure to the chemical by following proper handling procedures.


Fire and Explosion Hazards:

Polyhexamethylene biguanide hydrochloride is not flammable.
In case of fire involving other materials, use appropriate extinguishing agents such as water spray, foam, dry chemical, or carbon dioxide (CO2).


Accidental Release Measures:

Contain the spillage to prevent further spread of the chemical.
Absorb spilled material with inert absorbents such as sand or vermiculite.
Collect spilled material in appropriate containers for disposal according to local regulations.


Handling and Storage:

Handle Polyhexamethylene biguanide hydrochloride with care to prevent spills and accidental exposure.
Store in a cool, dry, well-ventilated area away from incompatible materials.
Keep containers tightly closed when not in use to prevent contamination.
Follow proper handling procedures to minimize the risk of exposure.


Exposure Controls/Personal Protection:

Use engineering controls such as ventilation systems to minimize exposure to the chemical.
Wear appropriate PPE, including gloves, safety goggles, and protective clothing, when handling Polyhexamethylene biguanide hydrochloride.
Wash hands thoroughly after handling the chemical and before eating, drinking, or smoking.


Environmental Precautions:

Prevent release into the environment by following proper handling and disposal procedures.
Avoid contamination of water sources, soil, and air.
Dispose of unused product and contaminated materials according to local regulations and guidelines.


Additional Information:

Provide additional information as necessary based on specific circumstances, such as the concentration of the chemical, the route of exposure, and the severity of symptoms.
Consult the safety data sheet (SDS) for detailed information on hazards, handling, and emergency procedures.
Keep emergency contact numbers and information readily available for quick reference in case of exposure or accidents.



HANDLING AND STORAGE


Handling Precautions:

Handle Polyhexamethylene biguanide hydrochloride (Polyhexanide) with care to minimize the risk of exposure.
Wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and protective clothing when handling the chemical.
Avoid inhalation of dust, vapors, or mists. Use local exhaust ventilation if handling in an enclosed space.
Wash hands thoroughly after handling Polyhexanide, especially before eating, drinking, smoking, or using the restroom.
Do not eat, drink, or smoke while handling the chemical.
Avoid contact with skin, eyes, and clothing. In case of contact, follow first aid measures as outlined in the safety data sheet (SDS).
Use Polyhexanide in a well-ventilated area to prevent the buildup of vapors or fumes.
Use appropriate engineering controls, such as closed systems or containment, to minimize exposure during handling and transfer operations.
Avoid generating dust or aerosols when handling solid forms of Polyhexanide. Use dust suppression techniques if necessary.
Do not mix Polyhexanide with incompatible substances or materials. Consult the SDS for information on compatibility.


Storage Conditions:

Store Polyhexamethylene biguanide hydrochloride in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed when not in use to prevent contamination and moisture ingress.
Store Polyhexanide away from incompatible materials such as strong acids, bases, oxidizing agents, and reducing agents.
Ensure proper labeling of containers with the product name, concentration, hazard symbols, and handling precautions.
Store large quantities of Polyhexanide in dedicated storage areas with appropriate containment measures in place.
Prevent spills and leaks by storing containers on compatible secondary containment systems.
Regularly inspect storage areas for signs of damage, leaks, or deterioration of containers.
Ensure that storage areas are equipped with spill control measures and cleanup materials in case of accidental spills or leaks.
Keep Polyhexanide out of reach of children and unauthorized personnel.
Follow local regulations and guidelines for the storage and handling of hazardous chemicals, including Polyhexamethylene biguanide hydrochloride.