Methyl tert-butyl ether is a volatile, flammable, and colorless liquid that is sparingly soluble in water.
The structure of Methyl tert-butyl ether consists of a methyl group (CH3) attached to a tertiary butyl group (t-butyl) with an oxygen atom in between.
Methyl tert-butyl ether is an organic compound classified as an ether.

CAS Number: 1634-04-4
Molecular Formula: C5H12O
Molecular Weight: 88.15
EINECS: 216-653-1

Methyl tert-Butyl Ether (MTBE) is a man-made chemical that raises the oxygen content of gasoline, allowing it to burn more cleanly in vehicles.
Methyl tert-butyl ether (MTBE), also known as methyl tert-butyl ether and tert-butyl methyl ether, is an organic compound with a structural formula (CH3)3COCH3.
Primarily used as a fuel additive, MTBE is blended into gasoline to increase its octane rating and knock resistance, and reduce unwanted emissions.

Methyl tert-butyl ether (MTBE) is a chemical compound with the molecular formula C5H12O.
Methyl tert-butyl ether is a clear, volatile liquid that is highly flammable.
It has a characteristic odor similar to that of diethyl ether.

Methyl tert-butyl ether was primarily used as a gasoline additive to enhance octane levels and improve the combustion properties of gasoline, thereby reducing engine knocking and improving overall engine performance.
Methyl tert-butyl ether was widely used in reformulated gasoline (RFG) to comply with environmental regulations aimed at reducing air pollution and smog formation.

Methyl tert-butyl ethers impact on groundwater contamination and potential health hazards led to its reduced use and eventual ban in some regions.
Methyl tert-butyl ether is known to be more soluble in water than many other gasoline components, making it a potential groundwater pollutant if gasoline containing Methyl tert-butyl ether leaks from storage tanks or spills occur.

Methyl tert-butyl ether, also known as MTBE or Methyl tert-butyl ether, is a clear, colorless liquid with a low viscosity that is combustible and has a distinct, turpentine-like odor.
It is miscible with organic solvents, but only slightly soluble in water.
Methyl tert-butyl ether is very stable under alkaline, neutral, and weakly acidic conditions.

In the presence of strong acids, Methyl tert-butyl ether is cleaved to methanol and isobutene.
Depending on reaction conditions the latter can form isobutene oligomers.
Methyl tert-butyl ether does not undergo autoxidation and, in contrast to other ethers, it does not form peroxides with atmospheric oxygen.

Methyl tert-butyl ether improves the antiknock properties when added to motor gasoline.
Methyl tert-butyl ether is manufactured via the chemical reaction of methanol and isobutylene.
Methanol is primarily derived from natural gas, where steam reforming converts the various light hydrocarbons in natural gas (primarily methane) into carbon monoxide and hydrogen.

The resulting gases then further react in the presence of a catalyst to form Methyl tert-butyl ether.
Isobutylene can be produced through a variety of methods.
n-butane can be isomerized into isobutane which can be dehydrogenated to isobutylene.

In the Halcon process, Methyl tert-butyl ether derived from isobutane oxygenation is reacted with propylene to produce propylene oxide and t-butanol.
The t-butanol can be dehydrated to isobutylene.
One of the primary reasons for using Methyl tert-butyl ether as a gasoline additive was its ability to boost the octane rating of gasoline.

Octane rating indicates a fuel's resistance to knocking or pre-ignition in internal combustion engines.
Higher octane ratings allow for higher engine compression ratios and improved performance.
Methyl tert-butyl ether has been a subject of environmental concern due to its potential to contaminate groundwater.

Methyl tert-butyl ethers high solubility in water makes it more likely to migrate into underground water sources in the event of gasoline leaks or spills.
Because of this, its use in gasoline has been significantly reduced or banned in many places.
In the 1990s and early 2000s, Methyl tert-butyl ether contamination of groundwater became a significant issue in some areas, particularly in the United States.

Leaks from underground gasoline storage tanks and accidental spills at gas stations were among the major sources of Methyl tert-butyl ether pollution in the environment.
Methyl tert-butyl ether is considered to have low acute toxicity to humans.
However, prolonged exposure to high levels of MTBE vapor or ingestion may cause health issues such as irritation of the respiratory system, skin, and eyes.

Methyl tert-butyl ether is also used in various industrial applications as a solvent in the production of chemicals, pharmaceuticals, and other products.
However, its use in these applications is generally more controlled compared to its use as a gasoline additive.
The regulations and legal status of Methyl tert-butyl ether vary from country to country.

Melting point: -110 °C
Boiling point: 55-56 °C(lit.)
Density: 0.7404
vapor density: 3.1 (vs air)
vapor pressure: 4.05 psi ( 20 °C)
refractive index: n20/D 1.369(lit.)
Flash point: -27 °F
storage temp.: Store at +2°C to +25°C.
solubility: 42g/l
form: Powder or Needles
color APHA: ≤10
Specific Gravity: 0.740
Odor: Characteristic ethereal odor
Relative polarity: 0.124
explosive limit: 1.5-8.5%(V)
Relative density, gas (air=1): 0.74 g/cm3 at 25 °C
Viscosity: 0.464mm2/s
Water Solubility: 51 g/L (20 ºC)
FreezingPoint: -108.6℃
λmax: λ: 210 nm Amax: 1.0
λ: 225 nm Amax: 0.50
λ: 250 nm Amax: 0.10
λ: 300-400 nm Amax: 0.005
Merck: 14,6032
BRN: 1730942
Exposure limits ACGIH: TWA 50 ppm
LogP: 1.06 at 20℃

Methyl tert-butyl ether is a liquid, colorless, volatile organic compound with a terpene-like odor, a vapor pressure of 249 mm Hg at 25° C, a water solubility of 51,000 mg/L, and a specific gravity of 0.74.
When released to the air, it has a 5 to 6 day half life and degrades primarily by reacting with photochemically produced hydroxyl radicals to form tertiary butyl formate.
The exposure to atmospheric UV light alone will not be sufficient to decompose this compound.

The low log Kow (1.24) suggests that Methyl tert-butyl ether will be very mobile in soils.
Methyl tert-butyl ether has a Henry's Constant of 0.022 and hence is not likely to form a vapor plume in the vadose zone above a dissolved phase plume.
Methyl tert-butyl ether is a gasoline additive.

Methyl tert-butyl ether undergoes oxidative degradation in the presence of propane-oxidizing bacterial strains.
The kinetic studies of heat-assisted persulfate oxidation of Methyl tert-butyl ether under various parameters suggests that the reaction follows the pseudo-first-order kinetics.
Methyl tert-butyl ether can be synthesized by acid catalyzed reaction between methanol and isobutene.

Methyl tert-butyl ether is an effective alternative to lead containing additives for enhancing the octane rating of gasoline.
A study suggests that the addition of Methyl tert-butyl ether increases the number of active sites during polymerization of propene by stopped-flow method.
Methyl tert-butyl ether may be used to synthesize fatty acid methyl esters (FAMEs) and glycerol tert-butyl ether via transesterification with canola oil under supercritical conditions.

Methyl tert-butyl ether (MTBE) is a flammable liquid that has been used as an additive for unleaded gasoline since the 1980s.
Methyl tert-butyl ether increases octane and oxygen levels in gasoline and reduces pollution emissions.
Because of concerns for groundwater contamination and water quality, Methyl tert-butyl ether is now banned or limited in several states.

Methyl tert-butyl ether's use as a gasoline additive was primarily as an oxygenate.
Oxygenates are compounds that contain oxygen and are added to gasoline to improve combustion and reduce emissions.
By promoting more complete combustion of fuel in the engine, oxygenates help reduce carbon monoxide (CO) and hydrocarbon emissions.

One of the significant environmental concerns associated with Methyl tert-butyl ether in gasoline was its potential to cause phase separation.
Methyl tert-butyl ether has a tendency to dissolve in water, and if gasoline containing MTBE comes into contact with water (such as in underground fuel storage tanks), it can mix with the water.
This leads to the formation of a separate Methyl tert-butyl ether-water layer at the bottom of the tank, creating a potential source of groundwater contamination.

In many regions, Methyl tert-butyl ether was gradually phased out and replaced with ethanol (ethyl alcohol) as an oxygenate in gasoline.
Ethanol is derived from renewable sources like corn or sugarcane, and its use as a fuel additive has gained popularity due to its lower environmental impact and potential to reduce greenhouse gas emissions compared to Methyl tert-butyl ether.

Methyl tert-butyl ether in Reformulated Gasoline (RFG): Reformulated gasoline, which is required in some areas to meet air quality standards, often included Methyl tert-butyl ether as one of the oxygenates to help reduce emissions.
However, concerns about its impact on the environment and water quality led to the transition away from Methyl tert-butyl ether in RFG formulations.

Methyl tert-butyl ether's use as a gasoline additive was not limited to a single country; it was employed worldwide in various gasoline blends.
The extent of its use, however, varied depending on regional regulations and environmental concerns.

Individuals working in industries where Methyl tert-butyl ether is used or produced may be at risk of occupational exposure.
Occupational health and safety guidelines are in place to protect workers from exposure to hazardous substances like Methyl tert-butyl ether.
Due to its flammable and volatile nature, Methyl tert-butyl ether requires careful handling and transportation to ensure safety.

Preparation
Methyl tert-butyl ether can be prepared by the reaction of potassium tert-butoxide and bromomethane.
Methyl tert-butyl ether also can be obtained by the acid-catalyzed addition of methanol to isobutene.

Suitable catalysts are solid acids such as bentonites, zeolites and – commonly used in industrial world scale MTBE-production units – macroporous acidic ion-exchange resins. The reaction is weakly exothermic with a heat of reaction of -37.7 kJ/mol.

Uses
Methyl tert-butyl ether (MTBE) was primarily used as a gasoline additive in unleaded gasoline in the United States prior to 2005, in the manufacture of isobutene, and as a chromatographic eluent especially in high pressure liquid chromatography.
It is also a pharmaceutical agent and can be injected into the gallbladder to dissolve gallstones (ATSDR, 1996).

Methyl tert-butyl ether is also used in the petrochemical industry.
By reversal of its formation reaction, MTBE can be cracked to isobutene and methanol on acidic catalysts at higher temperature than Methyl tert-butyl ether synthesis.
Methyl tert-butyl ether is used as a fuel component in fuel for gasoline engines.

Methyl tert-butyl ether is one of a group of chemicals commonly known as oxygenates because they raise the oxygen content of gasoline.
Methyl tert-butyl ether was commonly used as an oxygenate in gasoline to enhance its octane rating and improve combustion properties.
By raising the octane level, Methyl tert-butyl ether reduced engine knocking and allowed for higher engine compression ratios, resulting in improved engine performance.

As an oxygenate, Methyl tert-butyl ether helped gasoline burn more completely in engines, which led to reduced emissions of carbon monoxide (CO) and certain hydrocarbons, contributing to improved air quality in areas with high vehicular traffic.
Methyl tert-butyl ether was used in reformulated gasoline, required in some regions to meet air quality standards.

Apart from its use as a gasoline additive, Methyl tert-butyl ether found applications as a solvent in various industrial processes.
Methyl tert-butyl ether was used in the production of chemicals, pharmaceuticals, and other products.
Besides gasoline, Methyl tert-butyl ether was occasionally used as an octane booster in aviation and racing fuels.

Methyl tert-butyl ether is used in the following products: pharmaceuticals, perfumes and fragrances, laboratory chemicals, fuels and pH regulators and water treatment products.
Methyl tert-butyl ether has an industrial use resulting in manufacture of another substance (use of intermediates).
Methyl tert-butyl ether is used in the following areas: formulation of mixtures and/or re-packaging.

Methyl tert-butyl ether is used for the manufacture of: chemicals and rubber products.
Release to the environment of Methyl tert-butyl ether can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, as processing aid and as processing aid.
Other release to the environment of Methyl tert-butyl ether is likely to occur from: indoor use as reactive substance.

Methyl tert-butyl ether was used as a blending component in gasoline to enhance its octane rating and improve its combustion characteristics.
The ability to increase octane levels without significantly altering other properties of gasoline made Methyl tert-butyl ether an attractive additive for gasoline manufacturers.

As an oxygenate additive in gasoline, Methyl tert-butyl ether helped to increase the oxygen content of the fuel.
The presence of oxygen in the fuel promotes more complete combustion, leading to reduced emissions of carbon monoxide and unburned hydrocarbons, which are harmful pollutants contributing to air pollution and smog formation.

Methyl tert-butyl ether's solubility in gasoline helped improve the stability of gasoline blends during storage.
It acted as a dispersant for certain components, preventing the separation of gasoline constituents over time.

Methyl tert-butyl ether found applications as a solvent in various industries.
It was used in the manufacturing of paints, coatings, adhesives, and other chemical products.
Its solvency properties made it valuable for dissolving and processing various compounds.

Methyl tert-butyl ether was utilized as an extraction solvent in certain chemical processes, especially in the production of butadiene and isobutylene from refinery streams.
In some areas, Methyl tert-butyl ether was used as a cleaner burning alternative to other gasoline additives like ethanol or methylcyclopentadienyl manganese tricarbonyl (MMT).
Methyl tert-butyl ether is also used in small amounts as a laboratory solvent and for some medical applications.

Hazard
Methyl tert-butyl ether slightly toxic by ingestion and inhalation.
Methyl tert-butyl ether, flammable when exposed to heat or flame.
Upper respiratory tract irritant and kidney damage.

Environmental Fate
Methyl tert-butyl ether can be released during manufacturing or blending with gasoline; during the storage, distribution, and transfer of Methyl tert-butyl ether-blended gasoline; and from spills or leaks or fugitive emissions at automotive service stations (U.S. EPA, 1994a).

Vapor emissions from Methyl tert-butyl ether-blended gasoline may also contribute to atmospheric levels (U.S. EPA, 1988).
Methyl tert-butyl ether is not expected to persist in the atmosphere because it undergoes destruction from reactions with hydroxyl radicals.

Synonyms
tert-Butyl methyl ether
Methyl tert-butyl ether
1634-04-4
MTBE
2-Methoxy-2-methylpropane
Methyl t-butyl ether
Propane, 2-methoxy-2-methyl-
T-BUTYL METHYL ETHER
Methyl-tert-butyl ether
Methyl-t-butyl ether
2-Methyl-2-methoxypropane
Methyl tertiary-butyl ether
tert-butylmethylether
Ether, tert-butyl methyl
Methyl 1,1-dimethylethyl ether
tert-Butylmethyl ether
tert-C4H9OCH3
1,1-dimethylethyl methyl ether
2-methoxy-2-methyl-propane
CCRIS 7596
CHEBI:27642
HSDB 5847
methyl-tert-butyl-ether
Methyl tert butyl ether
EINECS 216-653-1
UN2398
Methyl Tertiary Butyl Ether
BRN 1730942
tert-butyl-d9 methyl ether
UNII-29I4YB3S89
DTXSID3020833
29I4YB3S89
MFCD00008812
EC 216-653-1
tBME
4-01-00-01615 (Beilstein Handbook Reference)
tert-BuOMe
methyl-t-butylether
t-butylmethyl ether
methyltertbutyl ether
tertbutylmethyl ether
1219795-06-8
Methyl-tert-butylether
tert-Butyl methyl ether, for HPLC, >=99.8% (GC)
Driveron
MeOtBu
tBuOMe
t-butylmethylether
methylterbutyloxide
methyltertbutylether
tertbutylmethylether
methyl t-butylether
methylt-butyl ether
t-BuOMe
t-butyl methylether
t-butyl-methylether
tert-butylmethyether
MTBE ACS grade
tert.butylmethylether
methyl-t-butyl-ether
t-butyl methyi ether
t-butyl-methyl ether
t-butyl-methyl-ether
methyl tert-butylether
methyl tertbutyl ether
methyl-tert.butylether
methyl-tertbutyl ether
methyl-tertbutyl-ether
methyltert-butyl ether
tert -butylmethylether
tert butylmethyl ether
tert-butyl-methylether
tert. butylmethylether
tert.-butylmethylether
tert.butyl-methylether
tert.butylmethyl ether
tertbutyl methyl ether
tertbutyl(methyl)ether
Tert-butyl methylether
methy tert-butyl ether
methyl ter-butyl ether
metyl tert-butyl ether
ter-butyl methyl ether
tert-buty methyl ether
tert-buyl methyl ether
(tert-butyl)methylether
methyl tert.-butylether
methyl tert.butyl ether
methyl-tert butyl ether
methyl-tert. butylether
methyl-tert.-butylether
methyl-tert.butyl ether
MTBE-HP
tert-butyl-methyl ether
tert-butyl-methyl-ether
tert. butyl-methylether
tert.-butyl methylether
tert.-butyl-methylether
tert.-butylmethyl ether
tert.butyl methyl ether
Tert butyl methyl ether
TERT-BUTOXYMETHANE
methyl tert.-butyl ether
methyl-tert. butyl ether
tert. butyl-methyl-ether
tert.-butyl methyl ether
tert.-butyl-methyl ether
tert.-butyl-methyl-ether
methyl-tertiarybutyl ether
tert. Butyl methyl ether
tertiary butylmethyl ether
methyl tert.- butyl ether
Epitope ID:122671
tertiary-butyl methyl ether
Tertiary butyl methyl ether
(CH3)3COCH3
DTXCID30833
Propano, 2-metoxi-2-metil-
methyl tert-butyl ether (mtbe)
CHEMBL1452799
MTBE (Methyl tert-butyl ether)
(METHYL)(TERT-BUTYL)ETHER
AMY11032
tert-Butylmethyl ether, HPLC Grade
Methyl tertiary butyl ether (MTBE)
T-BUTYL METHYL ETHER [INCI]
Tox21_201184
LS-917
NA2398
tert-Butyl methyl ether, HPLC grade
METHYL TERT-BUTYL ETHER [MI]
AKOS000121105
METHYL TERT-BUTYL ETHER [IARC]
tert-Butyl methyl ether, LR, >=99%
UN 2398
TERT-BUTYLMETHYL ETHER [USP-RS]
NCGC00091717-01
NCGC00091717-02
NCGC00258736-01
tert-Butyl methyl ether, p.a., 99.5%
CAS-1634-04-4
Methyl Tertiary Butyl Ether - High Purity
tert-Butyl methyl ether, AR, >=99.5%
B0991
tert-Butyl methyl ether, analytical standard
tert-Butyl methyl ether, anhydrous, 99.8%
tert-Butyl methyl ether, PRA grade, >=99%
tert-Butyl methyl ether, reagent grade, 98%
tert-Butyl methyl ether, for HPLC, >=99.8%
tert-Butyl methyl ether, for HPLC, >=99.9%
tert-Butyl methyl ether, reagent grade, >=98%
Methyl-tert-butylether 100 microg/mL in Methanol
Q412346
tert-Butyl methyl ether, ACS reagent, >=99.0%
tert-Butylmethyl ether 100 microg/mL in Methanol
InChI=1/C5H12O/c1-5(2,3)6-4/h1-4H
J-509782
Methyl tert-butyl ether 2000 microg/mL in Methanol
Methyl tert-butyl ether [UN2398] [Flammable liquid]
tert-Butyl methyl ether, puriss. p.a., >=99% (GC)
Methyl tert-butyl ether [UN2398] [Flammable liquid]
MTBE ACS grade trace metal grade, stainless steel drum
tert-Butyl methyl ether, HPLC grade, for HPLC, 99.8%
tert-Butyl methyl ether, puriss. p.a., >=99.5% (GC)
tert-Butyl methyl ether, SAJ special grade, >=99.0%
Methyl tert-butyl ether (MTBE) 1000 microg/mL in Methanol
tert-Butyl Methyl Ether, Pharmaceutical Secondary Standard; Certified Reference Material
tert-Butyl methyl ether, United States Pharmacopeia (USP) Reference Standard

2-Methoxy-2-methylpropane; methyl t-butyl ether;Tert-butyl methyl ether; Methyl Tertiary Butyl Ether; Methyl 1,1-dimethylethyl ether; 2-Methyl-2-methoxypropane; cas no: 1634-04-4

Methyl Tribromide is a brominated organic solvent, colorless liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.
Methyl Tribromide is widely used as a solvent for waxes, oils and greases.
Miscible with Methyl Tribromide, benzene, ethanol, petroleum ether, acetone, diethyl ether and oils.

CAS Number: 75-25-2
EC Number: 200-854-6
Molar Mass: 252.75 g/mol
Chemical Formula: CHBr3

Methyl Tribromide is a brominated organic solvent, colorless liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.
Methyl Tribromide is one of the four haloforms, the others being fluoroform, chloroform, and iodoform.

Methyl Tribromide can be prepared by the haloform reaction using acetone and sodium hypobromite, by the electrolysis of potassium bromide in ethanol, or by treating chloroform with aluminium bromide.
Currently Methyl Tribromide main use is as a laboratory reagent.

Methyl Tribromide is widely used as a solvent for waxes, oils and greases.
Methyl Tribromide is utilized for mineral ore separation in geological tests.

Methyl Tribromide is used as an intermediate in chemical synthesis as well as a laboratory reagent.
Methyl Tribromide is the ingredient of fire-resistant chemicals and fluid gauges.
Methyl Tribromide acts as a sedative and as cough reducing agent.

Methyl Tribromide is a brominated organic solvent with the formula CHBr3.
Methyl Tribromide has an odor similar to chloroform and Methyl Tribromide density is very high (2,89).
Miscible with chloroform, benzene, ethanol, petroleum ether, acetone, diethyl ether and oils.

Methyl Tribromide is classified as a member of the Trihalomethanes.
Trihalomethanes are organic compounds in which exactly three of the four hydrogen atoms of methane (CH4) are replaced by halogen atoms.
Trace amounts of 1,2-dibromoethane occur naturally in the ocean, where Methyl Tribromide is formed probably by algae and kelp.

Methyl Tribromide is formally rated as an unfounded non-carcinogenic (IARC 3) potentially toxic compound.
Exposure to Methyl Tribromide may occur from the consumption of chlorinated drinking water.

The acute (short-term) effects from inhalation or ingestion of high levels of Methyl Tribromide in humans and animals consist of nervous system effects such as the slowing down of brain functions, and injury to the liver and kidney.
Chronic (long-term) animal studies indicate effects on the liver, kidney, and central nervous system (CNS) from oral exposure to Methyl Tribromide.

Human data are considered inadequate in providing evidence of cancer by exposure to Methyl Tribromide, while animal data indicate that long-term oral exposure can cause liver and intestinal tumors.
Methyl Tribromide has been classified as a Group B2, probable human carcinogen.
Most of the Methyl Tribromide that enters the environment is formed as disinfection byproducts known as the trihalomethanes when chlorine is added to drinking water or swimming pools to kill bacteria.

In the past, Methyl Tribromide was used as a solvent, sedative and flame retardant, but now Methyl Tribromide is mainly used as a laboratory reagent.
Bromine is a halogen element with the symbol Br and atomic number 35.

Diatomic bromine does not occur naturally, but bromine salts can be found in crustal rock.
Methyl Tribromide is a pale yellow liquid at room temperature, with a high refractive index, very high density, and sweet odor is similar to that of chloroform.

Methyl Tribromide (CHBr3) is a brominated organic solvent, pale yellow liquid at room temperature, with a high refractive index, very highdensity, and sweet odor is similar to that of.
Methyl Tribromide is a trihalomethane, and is one of the four haloforms, the others beingfluoroform, and iodoform.

Methyl Tribromide can be prepared by the haloform reaction using acetone and sodium hypobromite, by the electrolysis of potassium bromide in ethanol, or by treating with aluminum bromide.
Currently Methyl Tribromide main use is as a laboratory reagent.

Methyl Tribromide is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 to < 1 000 tonnes per annum.
Methyl Tribromide is used in formulation or re-packing, at industrial sites and in manufacturing.

Methyl Tribromide (CHBr3) is a pale yellowish liquid with a sweet odor similar to chloroform, a halomethane or haloform.
Methyl Tribromide refractive index is 1.595 (20 °C, D).

Small amounts are formed naturally by plants in the ocean.
Methyl Tribromide is somewhat soluble in water and readily evaporates into the air.
Most of the Methyl Tribromide that enters the environment is formed as byproducts when chlorine is added to drinking water to kill bacteria.

Methyl Tribromide is one of the trihalomethanes closely related with fluoroform, chloroform and iodoform.
Methyl Tribromide is soluble in about 800 parts water and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone, and oils.
Methyl Tribromide LD50 is 7.2 mmol/kg in mice, or 1.8g/kg.

Methyl Tribromide can be prepared by the haloform reaction using acetone and sodium hypobromite or by the electrolysis of alcoholic solution of potassium or sodium bromide.

Methyl Tribromide is used as a solvent and to make pharmaceuticals.
Often stabilized with 1 to 3% ethanol.

Applications of Methyl Tribromide:
Methyl Tribromide is widely used as a solvent for waxes, oils and greases.
Methyl Tribromide is utilized for mineral ore separation in geological tests.

Methyl Tribromide is used as an intermediate in chemical synthesis as well as a laboratory reagent.
Methyl Tribromide is the ingredient of fire-resistant chemicals and fluid gauges.
Methyl Tribromide acts as a sedative and as cough reducing agent.

Uses of Methyl Tribromide:
As a fluid for mineral ore separation; as a laboratory reagent; in the electronics industry for quality assurance programs; formerly as a sedative and antitussive

Methyl Tribromide is a colorless to yellow liquid with a density about three times that of water.
Methyl Tribromide has an odor and sweetish taste similar to chloroform and is not combustible.

Methyl Tribromide has been used as a degreasing solvent, in chemical synthesis, and in fire extinguishers, and is no longer used as a sedative for children with whooping cough.
Currently, Methyl Tribromide is produced only in small amounts for use in laboratories and in geological and electronics testing.

In separating mixtures of minerals.
Methyl Tribromide is used as a fluid for mineral ore separation in geological tests, as a laboratory reagent, and in the electronics industry in quality assurance programs.

Methyl Tribromide was formerly used as a solvent for waxes, greases, and oils, as an ingredient in fire-resistant chemicals and in fluid gauges.
Methyl Tribromide was also used in the early part of this century as a medicine to help children with whooping cough get to sleep.
Currently, Methyl Tribromide is only produced in small amounts for use in laboratories and in geological and electronics testing.

Methyl Tribromide is used as a fluid for mineral ore separation in geological tests, as a laboratory reagent, and in the electronics industry in quality assurance programs.
Methyl Tribromide was formerly used as a solvent for waxes, greases, and oils, as an ingredient in fire-resistant chemicals and in fluid gauges.
Methyl Tribromide has also been used as an intermediate in chemical synthesis, as a sedative, and as a cough suppression agent.

Only small quantities of Methyl Tribromide are currently produced industrially in the United States.
In the past, Methyl Tribromide was used as a solvent, and flame retardant, but now Methyl Tribromide is mainly used as a laboratory reagent, for example as an extraction solvent.

Methyl Tribromide's high density makes Methyl Tribromide useful for separation of minerals by density.
When two samples are mixed with Methyl Tribromide and then allowed to settle, the top layer will contain minerals lighter than Methyl Tribromide, and the bottom layer will contain heavier minerals.
Slightly less dense minerals can be separated in the same way by mixing the Methyl Tribromide with a small amount of a less dense and fully miscible solvent.

Methyl Tribromide is used as a fluid for mineral ore separation in geological tests, as a laboratory reagent, and in the electronics industry in quality assurance programs.
Methyl Tribromide has also been used as an intermediate in chemical synthesis, as a sedative, and as a cough suppression agent.

Only small quantities of Methyl Tribromide are currently produced industrially in the United States.
In the past, Methyl Tribromide was used as a solvent, sedative and flame retardant, but now Methyl Tribromide is mainly used as a laboratory reagent, for example as an extraction solvent.

Methyl Tribromide also has medical uses; injections of Methyl Tribromide are sometimes used instead of epinephrine to treat severe asthma cases.

Methyl Tribromide's high density makes Methyl Tribromide useful for separation of minerals by density.
When two samples are mixed with Methyl Tribromide and then allowed to settle, the top layer will contain minerals less dense than Methyl Tribromide, and the bottom layer will contain denser minerals.
Slightly less dense minerals can be separated in the same way by mixing the Methyl Tribromide with a small amount of a less dense and miscible solvent.

Methyl Tribromide is known as an inhibitor of methanogenesis and is a common component of seaweed.
Following research by CSIRO and Methyl Tribromide spin-off FutureFeed, several companies are now growing seaweed, in particular from the genus Asparagopsis, to use as a feed additive for livestock to reduce methane emissions from ruminants.

Methyl Tribromide is used as a intermediate for pharmaceuticals and other organic compounds.
Methyl Tribromide is also used as a solvent for waxes and oils.

Methyl Tribromide is used for synth of pharmaceuticals; used in shipbuilding, aircraft, and aerospace industries; used in fire extinguishers.
Methyl Tribromide is used as a heavy liquid floatation agent in mineral separation, sedimentary petrographical surveys, and purification of materials such as quartz.

Methyl Tribromide is used as an industrial solvent in liquid-solvent extractions, in nuclear magnetic resonance studies.
Methyl Tribromide is used as a catalyst, initiator, or sensitizer in polymer reactions, and in vulcanization of rubber.

Use Classification of Methyl Tribromide:
Hazardous Air Pollutants (HAPs)

Health Hazards - Carcinogens

Therapeutic Uses of Methyl Tribromide:
Methyl Tribromide was formerly used as an antiseptic and sedative.

Typical Properties of Methyl Tribromide:

Chemical Properties:
Methyl Tribromide is a colorless to pale yellow liquid with a high refractive index, very high density, and sweetish odor is similar to that of chloroform.
Methyl Tribromide is slightly soluble in water and is nonflammable.
Methyl Tribromide can form in drinking water as a by-product from the reaction of chlorine with dissolved organic matter and bromide ions.

Physical properties:
Clear, colorless to yellow liquid with a chloroform-like odor.
Odor threshold concentration in water is 0.3 mg/kg

Methyl Tribromide is a colorless to pale yellow liquid with a sweetish odor.
The chemical formula for Methyl Tribromide is CBr3H and the molecular weight is 252.75 g/mol.

The vapor pressure for Methyl Tribromide is 5 mm Hg at 20 °C, and Methyl Tribromide has an octanol/water partition coefficient(log Kow) of 2.38.
Methyl Tribromide has an odor threshold of 1.3 parts per million (ppm).

Methyl Tribromide is slightly soluble in water and is nonflammable.
Methyl Tribromide can form in drinking water as a by-product from the reaction of chlorine with dissolved organic matter and bromide ions.

Manufacturing Methods of Methyl Tribromide:
Prepared from acetone and sodium hypobromite.

By heating acetone or ethanol with bromine and alkali hyroxide and recovery of distillation (similar to acetone process of chloroform).

Analytic Laboratory Methods of Methyl Tribromide:
To support studies exploring the relation between exposure to trihalomethanes (THMs) and health effects, we have developed an automated analytical method using headspace solid-phase microextraction coupled with capillary gas chromatography and mass spectrometry.

This method quantitates trace levels of THMs (chloroform, bromodichloromethane, dibromochloromethane, and Methyl Tribromide) and methyl tertiary-butyl ether in tap water.
Detection limits of less than 100 ng/L for all analytes and linear ranges of three orders of magnitude are adequate for measuring the THMs in tap water samples tested from across the United States.

Method: NIOSH 1003, Issue 3
Procedure: gas chromatography with flame ionization detection
Analyte: Methyl Tribromide
Matrix: air
Detection Limit: 6.0 ug/sample.

Method: ASTM D5790
Procedure: gas chromatography/mass spectrometry
Analyte: Methyl Tribromide
Matrix: treated drinking water, wastewater, and ground water
Detection Limit: 0.2 ug/L.

Method: EPA-EAD 601
Procedure: gas chromatography with electrolytic conductivity or microcoulometric detector
Analyte: Methyl Tribromide
Matrix: municipal and industrial discharges
Detection Limit: 0.2 ug/L.

Clinical Laboratory Methods of Methyl Tribromide:
To support studies exploring the relation between exposure to trihalomethanes (THMs) and adverse health effects, an automated analytical method was developed using capillary gas chromatography (GC) and high-resolution mass spectrometry (MS) with selected ion mass detection and isotope-dilution techniques.
This method quantified trace levels of THMs (including chloroform, bromodichloromethane, dibromochloromethane, and Methyl Tribromide) and methyl tert-butyl ether (MTBE) in human blood.

Analyte responses were adequate for measuring background levels after extraction of these volatile organic compounds with either purge-and-trap extraction or headspace solid-phase microextraction (SPME).
The SPME method was chosen because of Methyl Tribromide ease of use and higher throughput.

Detection limits for the SPME GC-MS method ranged from 0.3 to 2.4 ng/L, with linear ranges of three orders of magnitude.
This method proved adequate for measuring the THMs and MTBE in most blood samples tested from a diverse U.S. reference population.

Purification Methods of Methyl Tribromide:
The storage and stability of Methyl Tribromide and chloroform are similar.
Ethanol, added as a stabilizer, is removed by washing with H2O or with saturated CaCl2 solution, and the CHBr3, after drying with CaCl2 or K2CO3, is fractionally distilled.

Prior to distillation, CHBr3 has also been washed with conc H2SO4 until the acid layer is no longer coloured, then dilute NaOH or NaHCO3, and H2O.
A further purification step is fractional crystallisation by partial freezing.

Structure of Methyl Tribromide:
The molecule adopts tetrahedral molecular geometry with C3v symmetry.

MeSH Pharmacological Classification of Methyl Tribromide:

Carcinogens:
Substances that increase the risk of NEOPLASMS in humans or animals.
Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.

Teratogens:
An agent that causes the production of physical defects in the developing embryo.

Environment and Toxicology of Methyl Tribromide:
Natural production of Methyl Tribromide by phytoplankton and seaweeds in the ocean is thought to be Methyl Tribromide predominant source in the environment.

However, locally significant amounts of Methyl Tribromide enter the environment formed as disinfection byproducts known as trihalomethanes when chlorine is added to drinking water to kill bacteria.
Methyl Tribromide is somewhat soluble in water and readily evaporates into the air.

Methyl Tribromide is the main trihalomethane produced in beachfront salt water swimming pools with concentrations as high as 1.2 ppm (parts per million).
Concentrations in freshwater pools are 1000 times lower.
Occupational skin exposure limits are set at 0.5 ppm.

Methyl Tribromide may be hazardous to the environment, and special attention should be given to aquatic organisms.
Methyl Tribromide volatility and environmental persistence makes Methyl Tribromide's release, either as liquid or vapor, strongly inadvisable.

Methyl Tribromide can be absorbed into the body by inhalation and through the skin.
Methyl Tribromide is irritating to the respiratory tract, the eyes, and the skin, and may cause effects on the central nervous system and liver, resulting in impaired functions.

Methyl Tribromide is soluble in about 800 parts water and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone, and oils.
Methyl Tribromide LD50 is 7.2 mmol/kg in mice, or 1.8g/kg.

The International Agency for Research on Cancer (IARC) concluded that Methyl Tribromide is not classifiable as to human carcinogenicity.
The EPA classified Methyl Tribromide as a probable human carcinogen.

Safe Storage of Methyl Tribromide:
Separated from strong bases, oxidants, metals and food and feedstuffs.
Keep in the dark.
Ventilation along the floor.

Store only if stabilized.
Store in an area without drain or sewer access.
Provision to contain effluent from fire extinguishing.

Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Reactivity Profile of Methyl Tribromide:
Heating Methyl Tribromide to decomposition produces highly toxic fumes of carbon oxybromide (carbonyl bromide) and hydrogen bromide.
Reaction with powdered potassium or sodium hydroxide, Li or Na/K alloys, is violently exothermic.
Explosive reaction with crown ethers in the presence of potassium hydroxide.

Safety Profile of Methyl Tribromide:
Suspected carcinogen with experimental neoplastigenic data.
A human poison by ingestion.

Moderately toxic by intraperitoneal and subcutaneous routes.
Human mutation data reported.

Methyl Tribromide can damage the liver to a serious degree and cause death.
Methyl Tribromide has anesthetic properties simdar to those of chloroform, but is not sufficiently volatile for inhalation purposes and is far too toxic for human use.
As a sedative and antitussive Methyl Tribromide medicinal application has resulted in numerous poisonings.

Inhalation of small amounts causes irritation, provoking the flow of tears and saliva, and reddening of the face.
Abuse can lead to adhction and serious consequences.
Explosive reaction with crown ethers or potassium hydroxide.

Violent reaction with acetone or bases.
Incompatible with Li or NaK alloys.
When heated to decomposition Methyl Tribromide emits hghly toxic fumes of Br-.

First Aid of Methyl Tribromide:

EYES:
First check the victim for contact lenses and remove if present.
Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center.

Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN:
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing.
Gently wash all affected skin areas thoroughly with soap and water.

IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop.
IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop.

Provide proper respiratory protection to rescuers entering an unknown atmosphere.
Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION:
DO NOT INDUCE VOMITING.
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center.

Be prepared to transport the victim to a hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body.

DO NOT INDUCE VOMITING.
IMMEDIATELY transport the victim to a hospital.

OTHER:
Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring.
Recommendations from the physician will depend upon the specific compound, Methyl Tribromide chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure.

Fire Fighting of Methyl Tribromide:

SMALL FIRE:
Dry chemical, CO2, water spray or regular foam.

LARGE FIRE:
Water spray, fog or regular foam.
Move containers from fire area if you can do Methyl Tribromide without risk.
Dike fire-control water for later disposal; do not scatter Methyl Tribromide.

FIRE INVOLVING TANKS OR CAR/TRAILER LOADS:
Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Do not get water inside containers.

Cool containers with flooding quantities of water until well after fire is out.
Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank.

ALWAYS stay away from tanks engulfed in fire.
For massive fire, use unmanned hose holders or monitor nozzles; if this is impossible, withdraw from area and let fire burn.

Fire Fighting Procedures of Methyl Tribromide:

Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.

If material on fire or involved in fire:
Do not extinguish fire unless flow can be stopped.
Extinguish fire using agent suitable for type of surrounding fire (Material itself does not burn or burns with difficulty.)

Use water in flooding quantities as fog.
Cool all affected containers with flooding quantities of water.

Apply water from as far a distance as possible.
Use foam, dry chemical, or carbon dioxide.
Keep run-off water out of sewers and water sources.

Isolation and Evacuation of Methyl Tribromide:
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL:
Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE:
If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions.
Also, consider initial evacuation for 800 meters (1/2 mile) in all directions.

Spillage Disposal of Methyl Tribromide:

Personal protection:
Complete protective clothing including self-contained breathing apparatus.
Do NOT let this chemical enter the environment.

Collect leaking liquid in sealable containers.
Absorb remaining liquid in sand or inert absorbent.

Then store and dispose of according to local regulations.
Do NOT wash away into sewer.

Personal precautions, protective equipment and emergency procedures:
Wear respiratory protection.
Avoid breathing vapors, mist or gas.

Ensure adequate ventilation.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Disposal Methods of Methyl Tribromide:
Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U225, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.

Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations.
Concentrations shall be lower than applicable environmental discharge or disposal criteria.

Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur.
Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal.

If Methyl Tribromide is not practicable to manage the chemical in this fashion, Methyl Tribromide must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal.
Offer surplus and non-recyclable solutions to a licensed disposal company.

Contact a licensed professional waste disposal service to dispose of Methyl Tribromide.
Dissolve or mix Methyl Tribromide with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber; Contaminated packaging: Dispose of as unused product.

A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 °C and residence times of seconds for liquids and gases, and hours for solids.
A potential candidate for liquid injection incineration at a temperature range of 650 to 1,600 °C and a residence time of 0.1 to 2 seconds.

A potential candidate for fluidized bed incineration at a temperature range of 450 to 980 °C and residence times of seconds for liquids and gases, and longer for solids.
If packaged as an aerosol, be careful when releasing in an incinerator or Methyl Tribromide will blow past the combustion zone.

Preventive Measures of Methyl Tribromide:

Personal precautions, protective equipment and emergency procedures:
Wear respiratory protection.
Avoid breathing vapors, mist or gas.

Ensure adequate ventilation.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Precautions for safe handling:
Avoid contact with skin and eyes.
Avoid inhalation of vapor or mist.

Avoid contact with skin, eyes and clothing.
Wash hands before breaks and immediately after handling Methyl Tribromide.

Gloves must be inspected prior to use.
Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with Methyl Tribromide.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Nonfire Spill Response of Methyl Tribromide:
Do not touch or walk through spilled material.

Stop leak if you can do Methyl Tribromide without risk.
Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire.

SMALL SPILL:
Pick up with sand or other non-combustible absorbent material and place into containers for later disposal.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Prevent entry into waterways, sewers, basements or confined areas.

Identifiers of Methyl Tribromide:
CAS number: 75-25-2
EC index number: 602-007-00-X
EC number: 200-854-6
Hill Formula: CHBr₃
Molar Mass: 252.75 g/mol
HS Code: 2903 69 19
Quality Level: MQ200

Boiling point: 149.5 °C (1013 mbar)
Density: 2.89 g/cm3 (20 °C)
Flash point: 30 °C does not flash
Melting Point: 8.0 °C
Vapor pressure: 7.5 hPa (25 °C)
Solubility: 3.2 g/l

CAS Number: 75-25-2
Abbreviations: R-20B3
UN: 2515
Beilstein Reference: 1731048
ChEBI: CHEBI:38682
ChEMBL: ChEMBL345248
ChemSpider: 13838404
DrugBank: DB03054
ECHA InfoCard: 100.000.777
EC Number: 200-854-6
Gmelin Reference: 49500
KEGG: C14707
MeSH: Methyl Tribromide
PubChem CID: 5558
RTECS number: PB5600000
UNII: TUT9J99IMU
UN number: 2515
CompTox Dashboard (EPA): DTXSID1021374
InChI: InChI=1S/CHBr3/c2-1(3)4/h1H
Key: DIKBFYAXUHHXCS-UHFFFAOYSA-N
SMILES: BrC(Br)Br

Properties of Methyl Tribromide:
Chemical formula: CHBr3
Molar mass: 252.731 g·mol−1
Appearance: Colorless liquid
Density: 2.89 g mL−1
Melting point: −4 to 16 °C; 25 to 61 °F; 269 to 289 K
Boiling point: 147 to 151 °C; 296 to 304 °F; 420 to 424 K
Solubility in water: 3.2 g L−1 (at 30 °C)
log P: 2.435
Vapor pressure: 670 Pa (at 20.0 °C)
Henry's law constant (kH): 17 μmol Pa−1 kg−1
Acidity (pKa): 13.7
Magnetic susceptibility (χ): -82.60·10−6 cm3/mol
Refractive index (nD): 1.595

Molecular Weight: 252.73
XLogP3-AA: 2.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 0
Exact Mass: 251.76079
Monoisotopic Mass: 249.76284
Topological Polar Surface Area: 0 Ų
Heavy Atom Count : 4
Complexity: 8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Methyl Tribromide:
Assay (GC, area %) : ≥ 98.0 %
Identity (IR-spectrum): passes test
Density: 2.81
Melting Point: 8°C to 9°C
Boiling Point: 148°C to 150°C
Flash Point: None
UN Number: UN2515
Beilstein: 1731048
Merck Index: 14,1420
Refractive Index: 1.585
Quantity: 250g
Solubility Information: Slightly soluble in water.
Sensitivity: Light sensitive
Formula Weight: 252.73
Percent Purity: 97%
Chemical Name or Material: Methyl Tribromide, Stabilized with ethanol

Thermochemistry of Methyl Tribromide:
Heat capacity (C): 130.5 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): 6.1–12.7 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −549.1–−542.5 kJ mol−1

Related compounds of Methyl Tribromide:

Related alkanes:
Dibromomethane
Tetrabromomethane
1,1-Dibromoethane
1,2-Dibromoethane
Tetrabromoethane

Names of Methyl Tribromide:

Preferred IUPAC name:
Tribromomethane

Other names:
Bromoform
Methenyl tribromide
Methyl tribromide
Tribromomethane

Synonyms of Methyl Tribromide:
Tribromomethane
Methane tribromide
Methyl tribromide
Bromoform
tribromomethane
75-25-2
Methane, tribromo-
Tribrommethan
Methenyl tribromide
Methyl tribromide
Tribrommethaan
Tribromometan
Bromoforme
Bromoformio
CHBr3
RCRA waste number U225
NCI-C55130
UNII-TUT9J99IMU
NSC 8019
TUT9J99IMU
CHEBI:38682
MFCD00000128
Bromoforme
Bromoformio
Tribrommethaan
Tribrommethan
Tribromometan
CCRIS 98
Bromoform
MBR
HSDB 2517
EINECS 200-854-6
UN2515
RCRA waste no. U225
BRN 1731048
bromo form
AI3-28587
Tri bromo methane
WLN: EYEE
Bromoform, technical grade
DSSTox_CID_1374
DSSTox_RID_76118
DSSTox_GSID_21374
SCHEMBL18691
4-01-00-00082
BIDD:ER0622
Bromoform, puriss., 97.0%
CHEMBL345248
DTXSID1021374
NSC8019
Bromoform
AMY21869
BCP10566
Bromoform (stabilized with Ethanol)
NSC-8019
ZINC8101061
Tox21_200189
Bromoform 100 microg/mL in Methanol
Bromoform, 96%, stab. with ethanol
AKOS009031540
AT27291
Bromoform 5000 microg/mL in Methanol
DB03054
UN 2515
CAS-75-25-2
Bromoform, puriss., >=99.0% (GC)
NCGC00091318-01
NCGC00091318-02
NCGC00257743-01
BP-21414
I606
Tribromomethane (stabilized with Ethanol)
Tribromomethane 100 microg/mL in Methanol
B0806
FT-0623248
FT-0623471
S0653
T0348
Bromoform, amylene stabilized, analytical standard
Q409799
J-519947
Bromoform, contains 1-3% ethanol as stabilizer, 96%
F0001-1896
Bromoform - contains 60-120ppm 2-Methyl-2-butene as stabilizer
BROMOFORM (CONTAINS 60-120PPM 2-METHYL-2-BUTENE AS STABILIZER)
Bromoform, contains 60-120 ppm 2-methyl-2-butene as stabilizer, 99%
220-823-0
2909-52-6
Bromform
Bromoform
Bromoforme
Bromoformi
Bromoformio
Bromofórmio
Bromoformo
CHBr3
Methane, tribromo-
methyl tribromide
MFCD00000128
Tribrommethaan
Tribrommethan
tribromometano
tribromometano
tribromomethane
Tribromométhane
[75-25-2]
200-854-6MFCD00000128
4471-18-5
Bromoform - contains 60-120ppm 2-Methyl-2-butene as stabilizer
Bromoform|Tribromomethane
Bromoform-d
Bromoforme
Bromoforme
Bromoformio
Bromoformio
MBR
METHENYL TRIBROMIDE
Tri bromo methane
Tribrommethaan
Tribrommethaan
Tribrommethan
Tribrommethan
tribromo methane
Tribromometan
Tribromometan
Tribromomethane, Methane tribromide, Methyl tribromide
TRIBROMOMETHANE|TRIBROMOMETHANE
WLN: EYEE

MeSH of Methyl Tribromide:
bromoform
tribromomethane

MMA; 2-Methyl 2-propenoic acid, methyl ester; 2-(Methoxycarbonyl)-1-propene; 2-Methyl propenoic acid, methyl ester; Methacrylic acid, methyl ester; Methyl 2-methyl-2-propenoate 2-Methyl-2-propenoic acid methyl ester; 2-Propenoic acid, 2-methyl-, methyl ester; Acrylic acid, 2-methyl-, methyl ester; Metakrylan metylu; Methacrylate De Methyle; Methacrylsaeuremethyl Ester; Methyl 2-methyl Propenoate; Methyl 2-methyl-2-propenoate; Methyl apha-methyl Acrylate; Methyl-methacrylat; Methylester Kyseliny Methakrylove; Methylmethacrylaat; Methylmethacrylate; Metil Metacrilato; MME; Methylpropylene-2-carboxylate CAS NO:80-62-6

Methylal is a colorless liquid with a low boiling point, low viscosity and excellent dissolving power.
Methylal is the dimethyl acetal of formaldehyde.


CAS Number: 109-87-5
EC Number: 203-714-2
MDLNumber: MFCD00008495
Molecular Formula: C3H8O2 / CH2-(OCH3)2
Chemical formula: C3H8O2



SYNONYMS:
Methane, dimethoxy-, Dimethyl formal, Anesthenyl, Dimethoxymethane, Formal, Formaldehyde dimethyl acetal, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, (CH3O)2CH2, Methylenedioxydimethane, Metylal, UN 1234, Formaldehyde methyl ketal, 2,4-Dioxapentane, Dimethylacetal formaldehyde, Bis(methoxy)methane, dimethoxymethane, formaldehyde dimethylacetal, methoxymethyl methyl ether, methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde, methyl ketal, Methoxymethyl methylether, Methylal, Methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde dimethylacetal, Formaldehyde methyl ketal, Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, Metylal [Polish], [ChemIDplus] UN1234, Dimethoxymethane, Formal, Formaldehyde Dimethylacetal, Methoxymethyl Methyl Ether, Methylene Dimethyl Ether, Methane, dimethoxy-, Dimethyl formal, Anesthenyl, Dimethoxymethane, Formal, Formaldehyde dimethyl acetal, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, (CH3O)2CH2, Methylenedioxydimethane, Metylal, UN 1234, Formaldehyde methyl ketal, 2,4-Dioxapentane, Dimethylacetal formaldehyde, Bis(methoxy)methane, Dimethoxymethane, METHYLAL, 109-87-5,Formal, Methane, dimethoxy-, Formaldehyde dimethyl acetal, Dimethyl formal, Anesthenyl, 2,4-Dioxapentane, Methylene dimethyl ether, Bis(methoxy)methane, Methoxymethyl methyl ether, Metylal, Formaldehyde methyl ketal,
Formaldehyde dimethylacetal, bis(methyloxy)methane, Methylene glycol dimethylether, 7H1M4G2NUE, CHEBI:48341, Dimethoxy methane, MFCD00008495, HSDB 1820,
EINECS 203-714-2, UN1234, UNII-7H1M4G2NUE, Dimethylformal, AI3-16096, CCRIS 9397, Methylene Glycol Dimethyl Ether, Dimethoxy-Methane, Methylenedioxydimethane, METHYLAL [HSDB], METHYLAL [INCI], METHYLAL [MI], Dimethoxymethane 99.5%, Dimethylacetal formaldehyde, METHYLAL [WHO-DD], EC 203-714-2, CHEMBL15537, (CH3O)2CH2, DTXSID1025564, AKOS000120977, UN 1234, Dimethoxymethane, ReagentPlus(R), 99%, Methylal [UN1234], D0637, FT-0625028, NS00003248, Formaldehyde dimethyl acetal, analytical standard, Q411496, J-520340, InChI=1/C3H8O2/c1-4-3-5-2/h3H2,1-2H, F0001-0207, Formaldehyde dimethyl acetal, absolute, over molecular sieve (H2O <=0.01%), >=99.0% (GC), Dimethoxymethane, Formal, Formaldehyde dimethylacetal, Methoxymethyl methyl ether, Methylene dimethyl ether, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde dimethylacetal, Formaldehyde methyl ketal, Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, UN1234,
dimethoxymethane, formaldehyde dimethylacetal, methoxymethyl methyl ether, methylene dimethyl ether, (CH3O)2CH2, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Dimethylacetal formaldehyde, Formal, Formaldehyde dimethyl acetal, Formaldehyde methyl ketal,
Methane, dimethoxy-, Methoxymethyl methyl ether, Methylene dimethyl ether, Methylene glycol dimethylether, Methylenedioxydimethane, Metylal, UN 1234,
formaldehyde, dimethyl acetal, methanal, dimethyl acetal, 2,4-Dioxapentane, Anesthenyl, Bis(methoxy)methane, Dimethoxymethane, Dimethyl formal, Formal, Formaldehyde dimethyl acetal, Formaldehyde, methyl ketal, Methoxymethyl methylether, Methylal, Methylene dimethyl ether, Formaldehyde Dimethyl Ether, Dimethoxymethane, Formaldehyde dimethyl aceta, Dimethoxymethane, Formal, Formaldehyde Dimethylacetal, Methoxymethyl Methyl Ether, Methylene Dimethyl Ether,
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Methylal appears as a clear colorless liquid with a chloroform-like odor.
The flash point of Methylal is 0 °F.
The boiling point of Methylal is 42.3 °C.


The density of Methylal is 0.864 g / cm3 at 68 °F (20 °C).
Methylal is a colorless liquid with a low boiling point, low viscosity and excellent dissolving power.
Methylal has a chloroform-like odor and a pungent taste.


Methylal is the dimethyl acetal of formaldehyde.
Methylal is soluble in three parts water and miscible with most common organic solvents.
Methylal appears as a clear colorless liquid with a chloroform-like odor.


Flash point of Methylal is 0 °F.
Boiling point of Methylal is 42.3 °C.
Methylal's Vapors are heavier than air.


Methylal is an acetal that is the dimethyl acetal derivative of formaldehyde.
Methylal is an acetal and a diether.
Methylal is the dimethyl acetal of formaldehyde.


Methylal is soluble in three parts water and miscible with most common organic solvents
Methylal is a clear colorless liquid with a chloroform-like odor.
Methylal is soluble in water and miscible with common organic solvents like methanol and ethanol.


Methylal is a colorless liquid with the chemical formula C3H8O2.
Methylal is the dimethyl acetal of formaldehyde with unique properties, suitable for different applications.
Methylal is also known as formaldehyde dimethyl acetal, methylene dimethyl ether, and methoxymethyl methyl ether.


Methylal belongs to the following substance groups solvents.
Methylal is a colorless liquid with the chemical formula C3H8O2.
Methylal has a chloroform-like odor and a pungent taste.


Methylal is the dimethyl acetal of formaldehyde.
Methylal exhibits high solvent power, medium to low polarity/surface tension and low to high evaporation rate.
Methylal is functionally related to a methanediol.


Methylal is a colorless liquid.
Methylal is soluble in three parts water and miscible with most common organic solvents.
Methylal is primarily used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings. Another useful application of Methylal is to protect alcohols with a MOM ether in organic synthesis.


Methylal is a colorless liquid with a chloroform-like odor.
Methylal is an ether.
Methylal is a partial substitute for alcohols in gel.


In formulations of antibacterial gel and hand sanitizers, Methylal can replace 50% of the alcohol used.
Alcohol is scarce and this can be partly dissolved by using Methylal.
Methylal, also known as Dimethoxymethane or Formaldehyde dimethyl ether, is the dimethyl acetal of formaldehyde used as a solvent as well as in manufacturing resins, perfumes, adhesives, and protective coatings.


Methylal is the triester of ethanol and phosphoric acid and can be called "phosphoric acid, triethyl ester".
Methylal is a clear colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.
Density of Methylal is 0.864 g / cm3 at 68 °F (20 °C).


Vapors of Methylal is heavier than air.
Methylal is an acetal that is the dimethyl acetal derivative of formaldehyde.
Methylal is an acetal and a diether.


Methylal is functionally related to a methanediol.
Methylal is a colorless liquid with a harsh, sharp odor.
Methylal is a colorless yet highly volatile acetal solvent that is manufactured from Methanol.


Methylal has a chloroform-like odor and a pungent taste.
Methylal is the dimethyl acetal of formaldehyde.
Methylal is soluble in three parts water and miscible with most common organic solvents.


Another useful application of Methylal is to protect alcohols with a MOM ether in organic synthesis.
Methylal, is a colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.
Methylal is a colorless liquid.


Methylal is the triester of ethanol and phosphoric acid and can be called "phosphoric acid, triethyl ester".
Methylal is a clear colorless flammable liquid with a low boiling point, low viscosity and an excellent dissolving power.
Methylal has a chloroform-like odor and a pungent taste.


Methylal is the dimethyl acetal of formaldehyde.
Methylal is a colorless yet highly volatile acetal solvent that is manufactured from Methanol.
Methylal has an extremely low toxicity profile.


Methylal is incompatible with strong oxidizing agents and acids.
Methylal should be kept away from heat, hot surfaces, sparks, open flames and other ignition sources.
Methylal is a colourless liquid with excellent dissolving power.


Methylal is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Methylal is a colorless flammable liquid with a low boiling point, low viscosity and excellent dissolving power.


Methylal has a chloroform-like odor and a pungent taste.
Methylal is a colorless liquid with a chloroform-like odor.



USES and APPLICATIONS of METHYLAL:
Methylal is used as a solvent for adhesives and coatings, a fuel, and an intermediate for other organic compounds.
Methylal has been used as an anesthetic.
Methylal can also be used for blending with diesel.


Methylal is often used as a fuel, to manufacture other organic chemicals, and a compatibilizer of actives in solvent and water based recipes.
In personal care applications, methylal improves spray performance and reduces solvent amount in aerosol cans and pump sprays. Methylal has an extremely low toxicity profile.


Methylal is used as a fuel and a solvent and to manufacture other organic chemicals.
Methylal is used aerosol cans & Pump sprays.
Methylal has a comparable, strong, dissolving capacity, which means that the quality of this substance can be found again.


In the case of Ethyl Alcohol, an improvement in quality is possible, when part of the alcohol is replaced by Methylal, smaller drop sizes are possible and the drying time is greatly shortened.
Further application of Methylal is possible in creams and lotions. The rapid evaporation creates a nice cooling effect.


This property, together with the high dissolving power for UV filters, makes the solvent very useful for sun protection products.
Removing nail polish with Methylal, possibly in combination with Dioxolane, is very effective.
Also as a replacement for Acetone or Ethyl Acetate, Methylal has no intoxicating effect when used on the hands, close to the face.


Methylal is used hand Cleansers, Antibacterial Gels, Hair Sprays, Sun Protection, Nail Polish Remover.
Industrially, Methylal is primarily used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings.
Another application of Methylal is as a gasoline-additive for increasing octane number.


Methylal is often used as a fuel, to manufacture other organic chemicals, and a compatibilizer of actives in solvent and water based recipes.
Methylal is used as a solvent for adhesives and coatings, a fuel, and an intermediate for other organic compounds.
Methylal has been used as an anesthetic.


Methylal, or Dimethoxymethane, is a colorless liquid that acts as a solvent.
Methylal has a very strong dissolving capacity and can be used in many different applications.
Because of the rapid evaporation, Methylal is often used in aerosol cans, especially as a replacement for, for example, Methylene chloride or Ethyl alcohol.


Methylal is suitable for use in cosmetics, here it can be used in a number of product groups.
The most commonly used application is hair styling sprays, the Methylal is then usually used as a replacement for Methylene chloride or Ethyl alcohol (CAS 64-17-5).


Methylene chloride contains, among other things, the H351 (suspected carcinogen) warning and has been replaced by other solvents in cosmetic aerosol cans.
In personal care applications, Methylal improves spray performance and reduces solvent amount in aerosol cans and pump sprays.
Methylal is used in removing nail polish.


Methylal acts as a solvent and can be used in many different applications.
Methylal is used as a solvent in different industries.
Methylal is used to produce anion exchange resins, manufacture perfumes, paint stripping, etc.


Methylal is used reaction solvent manufacturing pharmaceuticals,
Adhesives, Gasoline-additive for increasing octane number, and Protective coatings.
Methylal is used Paint Stripping, and Aerosol cans.


Methylal is used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings.
Methylal has a very strong dissolving capacity and is used as an extraction solvent in manufacturing pharmaceuticals, aerosols, paints, and varnishes.
Plus, Methylal is used as a fuel additive for smoke reduction.


Methylal, also known, as dimethoxymethane is widely used as a solvent and in the manufacture of perfumes, resins, adhesives.
Besides methylal is applied to increase the octane number of gasoline.
Methylal is primarily used as a solvent and in the manufacture of perfumes, resins, adhesives, paint strippers and protective coatings.


Methylal can be used in many different applications.
Due to the rapid evaporation, Methylal is often used in aerosol cans.
Plus, Methylal is suitable for use in cosmetics.


For example, Methylal is used in hair styling sprays, creams and lotions.
Methylal is mostly used as a solvent in different industries.
Methylal is used as a solvent in the manufacture of pharmaceuticals, aerosols, paints, varnishes and cleanings.


Methylal is used glue formulations fragrances and pesticides.
Methylal is used fuel additive for smoke reduction.
Methylal is used paint stripping.


Methylal is used in the production of creams and lotions. Methylal is a suitable solvent for sun protection products.
Methylal, also known, as dimethoxymethane is widely used as a solvent and in the manufacture of perfumes, resins, adhesives.
Release to the environment of Methylal can occur from industrial use: in processing aids at industrial sites, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates) and for thermoplastic manufacture.


Release to the environment of Methylal can occur from industrial use: manufacturing of the substance.
Methylal is used in inks and coatings.
Methylal is a clear colourless liquid with a chloroform-like odour.


Methylal is soluble in water and is miscible with common organic solvents.
Methylal is used in different industries.
Methylal is used as a solvent in the manufacture of resins, adhesives, paint strippers and protective coatings.


Methylal is the dimethyl acetal of formaldehyde.
Methylal is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Methylal is used in the following products: coating products, air care products, lubricants and greases, fuels, washing & cleaning products, adhesives and sealants, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay and polishes and waxes.
Other release to the environment of Methylal is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Other release to the environment of Methylal is likely to occur from: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)) and indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints).


Besides Methylal is applied to increase the octane number of gasoline.
Methylal can be found in complex articles, with no release intended: machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines).


Methylal is used in the following products: lubricants and greases, coating products, explosives, fuels, hydraulic fluids, laboratory chemicals, plant protection products, polymers and washing & cleaning products.
Methylal is used for the manufacture of: .


Other release to the environment of Methylal is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Release to the environment of Methylal can occur from industrial use: formulation of mixtures and formulation in materials.


Methylal is used in the following products: fuels, hydraulic fluids, lubricants and greases, polymers, coating products, heat transfer fluids, laboratory chemicals, washing & cleaning products and extraction agents.
Methylal has an industrial use resulting in manufacture of another substance (use of intermediates).


-Methylal is a product which can be today biosourced up to 86,5% with incredible properties which can fit in various applications to optimize:
*Wetting
*Viscosity
*Drying time (in spray and aerosols)
*Solubilization of ingredients (resins, actives, grease,..)
That's really the key polyvalent product to improve performances of your formulations.
Moreover, Methylal is only flammable and not label for health or environment issue



SYNTHESIS AND STRUCTURE OF METHYLAL:
Methylal can be manufactured by oxidation of methanol or by the reaction of formaldehyde with methanol.
In aqueous acid, Methylal is hydrolyzed back to formaldehyde and methanol.

Due to the anomeric effect, Methylal has a preference toward the gauche conformation with respect to each of the C–O bonds, instead of the anti conformation.

Since there are two C–O bonds, the most stable conformation is gauche-gauche, which is around 7 kcal/mol more stable than the anti-anti conformation, while the gauche-anti and anti-gauche are intermediate in energy.
Since it is one of the smallest molecules exhibiting this effect, which has great interest in carbohydrate chemistry, Methylal is often used for theoretical studies of the anomeric effect.



METHYLAL MARKET OVERVIEW:
Methylal Market is forecast to reach $445 million by 2026, after growing at a CAGR of 1.5% during the forecast period from 2021-2026.
Methylal is also known as dimethoxymethane and is often produced by oxidizing methanol or through the reaction of formaldehyde and methanol.

Globally, rising demand for methylal as blowing agents for PU foams, growing pharmaceuticals industries, flourishing cosmetic industry, and extensive properties of methylal such as good solubility, low boiling point, and anti-carcinogenic are the prime growth drivers of the methylal market.

In addition, the emergence of methylal as an automotive fuel and diesel modification additive, increase in the adoption of methylal for application in newer industrial verticals will create new opportunities for the methylal market, which will then substantially drive the methylal market during the forecast period.



FUNCTIONS OF METHYLAL IN COSMETIC PRODUCTS:
*SOLVENT
Methylal dissolves other substances



PRODUCTION OF METHYLAL:
Methylal is produced through the reaction of methanol and formaldehyde in the presence of concentrated sulfuric acid.
The resultant methylal is distilled, and unreacted methanol is separated from the product for recycling to obtain methylal with a content of 85% or more.



ADVANTAGES OF METHYLAL:
*Excellent Stability
*A versatile replacement solvent
*Excellent water removal property from organic molecules
*Excellent stability in acidic or alkaline medium
*Good miscibility with water



ADVANTAGES OF METHYLAL INCLUDE:
*Excellent stability
*Excellent water removal property from organic molecules
*Rapid evaporation
*Low viscosity
*Excellent dissolving power



SOME PROPERTIES OF METHYLAL INCLUDE:
*Methylal's molar mass is 09 g. mol-1.
*Methylal's melting point is −105 °C.
*Methylal's boiling point is 42 °C.
*Methylal's density is 821 gcm–3



REAGENT IN ORGANIC SYNTHESIS OF METHYLAL:
Another useful application of Methylal is to protect alcohols with a methoxymethyl (MOM) ether in organic synthesis.
Methylal can be activated with phosphorus pentoxide in dichloromethane or chloroform.

This method is preferred to the use of chloromethyl methyl ether (MOMCl).
Phenols can also be MOM-protected using Methylal, p-toluenesulfonic acid.
Alternatively, MOMCl can be generated as a solution by treating Methylal with an acyl chloride in the presence of a Lewis acid catalyst like zinc bromide:

MeOCH2OMe + RC(=O)Cl → MeOCH2Cl + RC(=O)(OMe)).
Unlike the classical procedure, which uses formaldehyde and hydrogen chloride as starting materials, the highly carcinogenic side product bis(chloromethyl) ether is not generated



PRODUCTION OF METHYLAL:
Methylal is produced through the reaction of methanol and formaldehyde in the presence of an acidic catalyst.
Methylal is generally known that methylal can be produced in the presence of sulfuric acid.
Conventionally, the methylal production is of batch process in which reaction and product isolation are carried out separately.



STORAGE OF METHYLAL:
Methylal is an important raw material and an excellent solvent in industry.
Methylal should be kept separated from strong oxidants and strong bases.
Plus, Methylal should be stored in a cool, dry, and well-ventilated facility.



OTHER STORAGE CONDITIONS OF METHYLAL INCLUDE:
Methylal should be stored in an area without drain or sewer access.
Methylal should be stored away from direct sunlight.

Methylal should be stored in tightly closed containers.
Methylal should be stored away from incompatible substances.
Methylal should be kept away from heat, sparks, and flame.



STORAGE OF METHYLAL:
Methylal should be stored in a tightly closed container, away from direct sunlight.
Methylal should be stored in a cool, dry and well-ventilated facility away from incompatible substances.
Methylal should be kept away from heat, sparks, and flame.



INFORMATION ABOUT METHYLAL:
"Methyl" mostly refers to methanol (methyl alcohol) as alcoholic component or generally the methyl group as the smallest hydrocarbon residue with one carbon atom.
Dimethyl-, trimethyl- etc refer to two, three or more methyl groups.



PHYSICAL and CHEMICAL PROPERTIES of METHYLAL:
Beilstein Number: 1697025
MDL: MFCD00008495
CoE Number: 10031
XlogP3: 0.20 (estimated)
Molecular Weight: 76.09516000
Formula: C3H8O2
Appearance: Colorless clear liquid (estimated)
Assay: 95.00 to 100.00%
Water Content: ~0.1%
Food Chemicals Codex Listed: No
Specific Gravity: 0.85500 to 0.86200 @ 25.00 °C
Pounds per Gallon - (estimated): 7.114 to 7.173
Refractive Index: 1.35000 to 1.35600 @ 20.00 °C

Melting Point: -105.00 °C @ 760.00 mm Hg
Boiling Point: 42.00 °C @ 760.00 mm Hg
Vapor Pressure: 398.000000 mmHg @ 25.00 °C
Flash Point: 1.00 °F TCC (-17.22 °C)
Soluble in alcohol, water (244000 mg/L @ 16°C, experimentally determined)
Physical description: Colorless liquid with a chloroform-like odor.
Boiling point: 111°F
Molecular weight: 76.1
Freezing point/melting point: -157°F
Vapor pressure: 330 mmHg
Flash point: -26°F (open cup)
Vapor density: 2.6
Specific gravity: 0.86

Ionization potential: 10.00 eV
Lower explosive limit (LEL): 1.6%
Upper explosive limit (UEL): 17.6%
NFPA health rating: 1
NFPA fire rating: 3
NFPA reactivity rating: 1
EINECS: 203-714-2
Density: 0.8560 g/cm3
Melting Point: -104.8°C
Boiling Point: 45.238 °C at 760 mmHg
Vapor Pressure: 43.99 kPa at 20 °C
Flash point: -17.8 °C
Explosion Limits, Lower: 1.60 vol%
Explosion Limits, Upper: 17.60 vol%

Molecular formula: C3H8O2
Molecular weight: 76.08 g/mol
CAS number: 109-87-5
EC number: 203-714-2
IUPAC name: Dimethoxymethane
EC name: Dimethoxymethane
EINECS: 203-714-2
Density: 0.8560 g/cm3
Freezing Point/Melting Point: -104.8°C
Boiling Point: 45.238 °C at 760 mmHg
Vapor Pressure: 43.99 kPa at 20 °C
Flash point: -17.8 °C
Explosion Limits, Lower: 1.60 vol%
Upper: 17.60 vol%
Appearance: Colorless transparent liquid

CSA Number: 109-87-5
Molecular Formula: C3H8O2
Molecular Weight: 76.09 g/mol
Appearance: Clear colorless liquid
Flash point: 180°C
Boiling Point: 42°C-44°C
Freezing Point/Melting Point: 105°C
Auto Ignition Temperature: 237°C
IUPAC name: Dimethoxymethane
CAS Number: 109-87-5
Density: 0.821 g/cm3
Boiling Point: 42 °C
Flashpoint: -31 °C
Melting Point: −105 °C

Chemical formula: C3H8O2
Molar mass: 76.095 g•mol−1
Appearance: Colorless liquid
Odor: Chloroform-like
Density: 0.8593 g cm−3 (at 20 °C)
Melting point: −105 °C (−157 °F; 168 K)
Boiling point: 42 °C (108 °F; 315 K)
Solubility in water: 33% (20 °C)
Vapor pressure: 330 mmHg (20 °C)
Magnetic susceptibility (χ): −47.3•10−6 cm3/mol
Molecular Weight: 76.09 g/mol
XLogP3: 0.2

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 2
Exact Mass: 76.052429494 g/mol
Monoisotopic Mass: 76.052429494 g/mol
Topological Polar Surface Area: 18.5Ų
Heavy Atom Count: 5
Formal Charge: 0
Complexity: 12.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Molecular formula: C3H8O2
Molecular weight: 76,08
CAS number: 109-87-5
EC number: 203-714-2
IUPAC name: Dimethoxymethane
EC name: Dimethoxymethane
Boiling point (°C) at 1013 hPa: 42.3
Freezing point (°C) at 1013 hPa: -104.8
Flash-point (°C) at 1013 hPa :-30.5
Relative density at 20°C: 0.861

Vapour pressure (kPa) at 20°C: 40
Surface tension (mN/m) at 20°C: 21.2
Water solubility (g/L) at 20°C Methylal in water: 330
Viscosity (kinematic) (mm²/s) at 25°C: 0.371
Evaporation rate compared to Diethyl ether (= 1): 1.36
Butyl acetate (= 1): 0.11
Physical state: clear, liquid
Color: colorless
Odor: pungent
Melting point/freezing point:
Melting point/range: -105 °C - lit.
Initial boiling point and boiling range: 41 - 42 °C - lit.

Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 19,9 %(V)
Lower explosion limit: 2,2 %(V)
Flash point: -18 °C - closed cup
Autoignition temperature: 260 °C at 1.013 hPa
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 0,325 mPa.s at 20 °C
Water solubility 330 g/l at 20 °C - soluble
Partition coefficient: n-octanol/water: No data available
Vapor pressure: 439,8 hPa at 20 °C 1.548,8 hPa at 55 °C

Density: 0,86 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information:
Surface tension: 21,2 mN/m at 20 °C
Relative vapor density: 2,63 - (Air = 1.0)
Boiling point: 111°F
Molecular weight: 76.1

Freezing point/melting point: -157°F
Vapor pressure: 330 mmHg
Flash point: -26°F (open cup)
Vapor density: 2.6
Specific gravity: 0.86
Ionization potential: 10.00 eV
Lower explosive limit (LEL): 1.6%
Upper explosive limit (UEL): 17.6%
NFPA health rating: 1
NFPA fire rating: 3
NFPA reactivity rating: 1



FIRST AID MEASURES of METHYLAL:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water. Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLAL:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area



FIRE FIGHTING MEASURES of METHYLAL:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLAL:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Splash contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 120 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLAL:
-Precautions for safe handling:
*Hygiene measures:
Change contaminated clothing.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Handle and open container with care.



STABILITY and REACTIVITY of METHYLAL:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .

Methylchloroisothiazolinone (MCI), also referred to as MCI, is the organic compound with the formula S(C2HCl)C(O)N(CH3).
Methylchloroisothiazolinone (MCI) is a white solid that melts near room temperature.
Methylchloroisothiazolinone (MCI) is an isothiazolinone, a class of heterocycles used as biocides.

CAS: 26172-55-4
MF: C4H4ClNOS
MW: 149.6
EINECS: 247-500-7

Synonyms
4-Isothiazolin-3-one,5-chloro-2-methyl-;5-chloro-2-methyl-3(2h)-isothiazolon;5-chloro-2-methyl-4-isothiazolin-3-on;Isothiazolinone;5-Chloro-2-methyl-4-isothiazolinone;5-CHLORIDE-2-METHYL-4-ISOTHIAZOLINE-3-KETONE;5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (CMI);5-CHLORO-2-METHYL-3(2H)-ISOTHIAZOLONE MIXED WITH 2-METHYL-3(2H)ISOTHIAZOLONE;5-Chloro-2-methyl-4-isothiazolin-3-one;26172-55-4;Methylchloroisothiazolinone;CMIT;Chloromethylisothiazolinone;5-Chloro-2-methyl-3(2H)-isothiazolone;5-Chloro-2-methyl-3-isothiazolone;3(2H)-Isothiazolone, 5-chloro-2-methyl-;5-Chloro-2-methyl-2H-isothiazol-3-one;5-chloro-N-methylisothiazolone;5-chloro-2-methylisothiazolin-3-one;5-chloro-2-methylisothiazol-3(2h)-one;5-chloro-n-methylisothiazolin-3-one;HS 818;n-methyl-5-chloroisothiazolone;5-chloro-2-methyl-1,2-thiazol-3-one;4-ISOTHIAZOLIN-3-ONE, 5-CHLORO-2-METHYL-;5-chloro-2-methyl-4-isothiazoline-3-one;DEL7T5QRPN;N-Methyl-5-chloroisothiazolin-3-one;5-chloro-2-methyl-3(2H)-isothiazolinone;DTXSID9034286;CHEBI:53621;2,3-Dihydro-2-methyl-3-oxo-5-chloroisothiazole;Kathon CG 5243;NCGC00181041-01;Bioace;5-chloro-2-methyl-1,2-thiazol-3(2H)-one;5-Chloro-2-methyl-3-isothiazolone (~90%);Kathon IXE;5-Chloro-2-methyl-4-isothiazolin-3-one, tech grade, >14% in water. CMI/MI >2.0;5-chloro-2-methyl-2,3-dihydro-1,2-thiazol-3-one;DTXCID7014286;5-Chloro-2-methyl-4-isothiazolin-3-one 100 microg/mL in Acetonitrile;N-Methyl-5-chloroisothiazolone (5-Chloro-2-methyl-4-isothiazolin-3-one);CAS-26172-55-4;A 33 (bactericide);UNII-DEL7T5QRPN;HS 818 (antiseptic);EINECS 247-500-7;BRN 1210149;5-Chloro-2-methyl-4-isothiazolin-3-one D3 (methyl D3);2-Methyl-5-chloro-3-isothiazolone;5-chloro-2-methyl-isothiazol-3-on;2-Methyl-5-chloroisothiazolin-3-one;5-chloro-2-methyl-2h-isothiazolin-3-one;T 360;SCHEMBL20686;SCHEMBL111860;CHEMBL1738962;HSDB 8270;Tox21_112689;Tox21_300199;HS-818;MFCD00792550;AKOS006230760;1ST2157;CS-W022348;DB14197;GS-3223;METHYLCHLOROISOTHIAZOLINONE [II];METHYLCHLOROISOTHIAZOLINONE [MI];5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE (ACTIVE INGREDIENT >14%, CMI/MI 2.5 - 4.0);NCGC00181041-02;NCGC00254127-01;55965-84-9 CMIT, MIT;AM806586;METHYLCHLOROISOTHIAZOLINONE [VANDF];2682-20-4 MIT;5-Chloro-2-methyl-isothiazol-3(2H)-one;METHYLCHLOROISOTHIAZOLINONE [MART.];DB-007017;METHYLCHLOROISOTHIAZOLINONE [WHO-DD];NS00000256;5-CHLOR-2-METHYL-4-ISOTHIAZOLIN-3-ONE;H10371;SBI-0654074.0001;EN300-7409393;Q204121;SR-01000944864;SR-01000944864-1;W-107193;Z2417817741;5-Chloro-2-methyl-4-isothiazolin-3-one (CMI/MI > 2.0)

Methylchloroisothiazolinone (MCI) have an active sulphur moiety that is able to oxidize thiol-containing residues, thereby effectively killing most aerobic and anaerobic bacteria.
Methylchloroisothiazolinone (MCI) is often used in combination with methylisothiazolinone, a mixture known as Kathon.
The Methylchloroisothiazolinone (MCI) have attracted attention because they can cause contact dermatitis.
Methylchloroisothiazolinone (MCI) is effective against gram-positive and gram-negative bacteria, yeast, and fungi.
Methylchloroisothiazolinone (MCI) is a heterocyclic chemical compound related to isothiazole.
Methylchloroisothiazolinone (MCI) is an antimicrobial preservative that is often used to control fungi, bacteria, and algae.

Since water-containing solutions are the breeding grounds for bacteria, Methylchloroisothiazolinone (MCI) can easily be used in such solutions.
Methylchloroisothiazolinone (MCI) is contained, along with methylisothiazolinone (MI), in Kathon cosmetic grade (CG) and MCI/MI.
Methylchloroisothiazolinone (MCI) is irritant and sensitizer.
A Methylchloroisothiazolinone (MCI) bearing a methyl group on the nitrogen atom and a chlorine at C-5.
Methylchloroisothiazolinone (MCI) is a powerful biocide and preservative and is the major active ingredient in the commercial product KathonTM.

Methylchloroisothiazolinone (MCI) is a 1,2-thiazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom and a chlorine at C-5.
Methylchloroisothiazolinone (MCI) is a powerful biocide and preservative and is the major active ingredient in the commercial product Kathon(TM).
Methylchloroisothiazolinone (MCI) has a role as an antimicrobial agent, a xenobiotic and an environmental contaminant.
Methylchloroisothiazolinone (MCI) is a member of 1,2-thiazoles and an organochlorine compound.
Methylchloroisothiazolinone (MCI) is functionally related to a methylisothiazolinone.
Methylchloroisothiazolinone (MCI) is an isothiazolinone commonly used as a preservative with antibacterial and antifungal properties.
Methylchloroisothiazolinone (MCI) is found within many commercially available cosmetics, lotions, and makeup removers.
Methylchloroisothiazolinone (MCI) is also a known dermatological sensitizer and allergen; some of its side effects include flaky or scaly skin, breakouts, redness or itchiness, and moderate to severe swelling in the eye area.

Methylchloroisothiazolinone (MCI) Chemical Properties
Melting point: 42-45C
Boiling point: 109.7°C
Density: 1.25 (14% aq.)
Refractive index: n20/D 1.378
Storage temp.: Refrigerator
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
pka: -4.06±0.40(Predicted)
Form: Liquid
Stability: Stable. Incompatible with strong oxidizing agents.
LogP: 0.240 (est)
CAS DataBase Reference: 26172-55-4(CAS DataBase Reference)
NIST Chemistry Reference: Methylchloroisothiazolinone (MCI)(26172-55-4)
EPA Substance Registry System: Methylchloroisothiazolinone (MCI) (26172-55-4)

Applications
Although Methylchloroisothiazolinone (MCI) have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials.
Notably, various products that use Methylchloroisothiazolinone (MCI) are in the market, including shampoo, hand sanitizer, and lotions.
Methylchloroisothiazolinone (MCI) is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.
Methylchloroisothiazolinone (MCI) is a high performance biocide for preserving metal working fluids, hydraulic fluids, polymer emulsions, pigment dispersions.

Suggested applications: preservative concentrate.
Very low level.
Methylchloroisothiazolinone (MCI) is a cost-effective antimicrobial for personal care formulations.
Suggested applications: personal care preservative.
Methylchloroisothiazolinone (MCI) is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems.
Suggested applications: Industrial water treatment.
Very low use levels.
A Methylchloroisothiazolinone (MCI) derivative as antimicrobial.
Methylchloroisothiazolinone (MCI) was tested for inhibition of PCAF activity. 5-Methylchloroisothiazolinone (MCI) showed the most potent inhibition of PCAF.

Methylchloroisothiazolinone (MCI) is found in many water-based personal care products and cosmetics.
Methylchloroisothiazolinone (MCI) was first used in cosmetics in the 1970s.
Methylchloroisothiazolinone (MCI) is also used in glue production, detergents, paints, fuels, and other industrial processes.
Methylchloroisothiazolinone (MCI) is known by the registered tradename Kathon CG when used in combination with methylisothiazolinone.
Methylchloroisothiazolinone (MCI) may be used in combination with other preservatives including ethylparaben, benzalkonium chloride, bronopol and phenoxyethanol.

Hazards
Methylchloroisothiazolinone (MCI) can cause allergic reactions in some people.
The first publication of the preservative as a contact allergen was in 1988.
Cases of photoaggravated allergic contact dermatitis, i.e. worsening of skin lesions after sun exposure, have also been reported.
In pure form or in high concentrations, Methylchloroisothiazolinone (MCI) is a skin and membrane irritant and causes chemical burns.
In the United States, maximum authorized concentrations are 15 ppm in rinse-offs (of a mixture in the ratio 3:1 of 5-chloro-2-methylisothiazol 3(2H)-one and 2-methylisothiazol-3 (2H)-one).
In Canada, Methylchloroisothiazolinone (MCI) may only be used in rinse-off products in combination with methylisothiazolinone, the total concentration of the combination may not exceed 15 ppm.

N° CAS : 35691-65-7, Nom INCI : METHYLDIBROMO GLUTARONITRILE. Conservateur : Inhibe le développement des micro-organismes dans les produits cosmétiques.2-bromo-2-(bromomethyl)pentanedinitrile (DBDCB), Synonymes : methyldibromoglutaronitrile;Glutaronitrile, 2-bromo-2-(bromomethyl)-;1,2-Dibromo-2,4-dicyanobutane;2-Bromo-2-(bromomethyl)pentanedinitrile;1-bromo-(bromoethyl)-1,3-propanedicarbonitrile;1-Bromo-1-(bromomethyl)-1,3-propanedicarbonitrile;2, 3-Dibromo-2,4-cyanobutane;2-Bromo-2-(bromomethyl) pentanedinitrile;2-Bromo-2-(bromomethyl)glutaronitrile;Dibromodicyanobutane;MDBGN;Metacide 38;Pentanedinitrile, 2-bromo-2-(bromomethyl)-;Tektamer 38;USEPA/OPP Pesticide Code: 111001.

N° CAS : 105-59-9, Nom INCI : METHYL DIETHANOLAMINE, Nom chimique : N-Methyldiethanolamine, METHYL DIETHANOLAMINE, Noms français : 2,2'-Methyliminodiethanol; Diethanolmethylamine; Méthyl diethanolamine; Méthylimino diéthanol-2,2'; N-Methyldiethanolamine; N-Méthyl diéthanolamine. Noms anglais : Ethanol, 2,2'-(methylimino)bis-; Methyldiethanolamine ,2'-(Methylimino)diethanol, 2,2'-Methyliminodiethanol, 2,2`-(Methylimino)bis-ethanol, 2-(N-2-Hydroxyethyl-N-methylamino)ethanol, 2-[2-hydroxyethyl(methyl)amino]ethanol, 4-04-00-01517 (Beilstein Handbook Reference), Bis(2-hydroxyethyl) methyl amine, Bis(2-hydroxyethyl)methylamine, C5H13NO2, Diethanolmethylamine, EINECS 203-312-7, Ethanol, 2,2'-(methylimino)bis-, Ethanol, 2,2'-(methylimino)di-, LS-389, MDEA, Methylbis(2-hydroxyethyl)amine, Methyldiethanolamine, Methyliminodiethanol, N,N-Bis(2-hydroxyethyl)methylamine, N,N-Di(2-hydroxyethyl)-N-methylamine, N-Methyl-2,2'-iminodiethanol, N-Methylaminodiglycol, N-METHYLDIETHANOLAMINE, n-methyl diethanolamine,N-Methyldiethanolimine, N-Methylimino-2,2'-diethanol, N-Methyliminodiethanol,N° EINECS/ELINCS : 203-312-7. Ses fonctions (INCI) : Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles. Noms français : 2,2'-Methyliminodiethanol; Diethanolmethylamine; Méthyl diethanolamine; Méthylimino diéthanol-2,2'; N-Methyldiethanolamine; N-Méthyl diéthanolamine. Noms anglais : Ethanol, 2,2'-(methylimino)bis-; Methyldiethanolamine

Methyldiethanolamine is a colorless liquid.
Methyldiethanolamine is a colorless to yellow liquid tertiary amine compound with an ammonia-like odor.
Methyldiethanolamine is a dihydroxy functional tertiary amine.


CAS Number: 105-59-9
EC Number: 203-312-7
MDL number: MFCD00002848
Molecular Formula: C5H13NO2 / CH3N(C2H4OH)2


Methyldiethanolamine is a colorless liquid.
Methyldiethanolamine is very water soluble .
Methyldiethanolamine is a clear, Colorless or Pale Yellow liquid with Ammonical Odor.


Methyldiethanolamine is miscible with water, alcohol and benzene.
Methyldiethanolamine is also known as a MDEA or N-Methyl Diethanolamine.
Methyldiethanolamine is versatile bifunctional molecules compound that combines the characteristic of Amine and hydroxyl group.


So, during the reaction, Methyldiethanolamine behaves like Alcohol and Amine Group but Amine group usually exhibits the greater activities.
Methyldiethanolamine can be modified with the help of some additives, the product is known as an activated Methyl Diethanolamine.
Methyldiethanolamine is a tertiary amine.


Methyldiethanolamine is capable of undergoing reactions typical of both alcohols and amines, forming Quaternary amine salts, soaps, and esters.
Methyldiethanolamine is an alkyl alkanolamine that is used in gas treatment applications and serves as an intermediate in the synthesis of numerous products.


Methyldiethanolamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
Methyldiethanolamine is a colorless to yellow liquid tertiary amine compound with an ammonia-like odor.


Methyldiethanolamine is completely soluble in water.
Methyldiethanolamine is a dihydroxy functional tertiary amine.
Methyldiethanolamine is a versatile intermediate with a variety of applications.


Methyldiethanolamine is a versatile, polyfunctional molecule that combines thecharacteristics of amines and alcohols.
Methyldiethanolamine is a colorless or dark yellow oily liquid.
Freezing point of Methyldiethanolamine is -21 °c.


Boiling point of Methyldiethanolamine is 247.2 °c.
Flash point of Methyldiethanolamine is 260 °c.
The relative density of Methyldiethanolamine was 1. 0377.


Refractive index of Methyldiethanolamine is 4678.
Methyldiethanolamine is miscible with water and alcohol.
Methyldiethanolamine is slightly soluble in ether.



USES and APPLICATIONS of METHYLDIETHANOLAMINE:
Methyldiethanolamine is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Methyldiethanolamine is used in the following products: washing & cleaning products.


Other release to the environment of Methyldiethanolamine is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).


Methyldiethanolamine can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones).
Methyldiethanolamine is used in the following products: coating products, lubricants and greases, metal working fluids, polymers, laboratory chemicals, pH regulators and water treatment products and washing & cleaning products.


Methyldiethanolamine is used in the following areas: building & construction work and scientific research and development.
Methyldiethanolamine is used for the manufacture of: and plastic products.
Other release to the environment of Methyldiethanolamine is likely to occur from: indoor use as processing aid.


Other release to the environment of Methyldiethanolamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Methyldiethanolamine is used in the following products: polymers.


Release to the environment of Methyldiethanolamine can occur from industrial use: formulation of mixtures.
Methyldiethanolamine is used in the following products: laboratory chemicals, coating products, pH regulators and water treatment products, lubricants and greases, metal working fluids and polymers.


Release to the environment of Methyldiethanolamine can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), of substances in closed systems with minimal release, in the production of articles and as processing aid.


Release to the environment of Methyldiethanolamine can occur from industrial use: manufacturing of the substance.
Methyldiethanolamine is used as a co-initiator for type II photoinitiator combinations.
As a neutralizing agent, Methyldiethanolamine increases resin solubility and improves solution stability by reducing pH drift.


Additionally, Methyldiethanolamine aids pigment dispersion.
Foams and Elastomers: Methyldiethanolamine can be used as a chain extender during the synthesis of polyol-based polyurethane foams and elastomers.
Inks: Methyldiethanolamine is used as a co-initiator for type II photoinitiator combinations.


As a neutralizing agent, Methyldiethanolamine increases resin solubility and improves solution stability by reducing pH drift. Additionally, Methyldiethanolamine aids pigment dispersion.
Metal Working: In metal working fluids, Methyldiethanolamine is used both as a pH buffer as well as an anticorrosion additive.


Textiles: Methyldiethanolamine forms quat salts with fatty acids which then find application in fabric softener formulations.
Methyldiethanolamine is used Urethanes, Paper Chemicals, Textile Softners, Pharmaceuticals, Gas scrubbing (CO2, H2S removal in natural, refining gas, ammonia hydrogen unit), Dyes and Polyurethane


Methyldiethanolamine is also a precursor to mechlorethamine (Bis(2-chloroethyl)methylamine), a nitrogen mustard chemical warfare agent developed for use as a vesicant or blister agent, similar to sulfur mustards.
Itself a dual-use chemical, Methyldiethanolamine has also been used as a chemotherapy agent in the treatment of Hodgkin lymphoma, leukaemia, and lung cancer.


Methyldiethanolamine is used in the following areas: building & construction work and scientific research and development.
Methyldiethanolamine is used for the manufacture of: chemicals, and plastic products.
Uses of Methyldiethanolamine: component of metal-working fluids; industrial chemical intermediate; corrosion inhibitor


Methyldiethanolamine is used as an intermediate in the synthesis of numerous products.
Methyldiethanolamine's unique chemistry has resulted in its use in diverse areas, including coatings, textile lubricants, polishes, detergents, pesticides, personal-care products, pharmaceuticals, urethane catalysts, and water-treatment chemicals.


Methyldiethanolamine is also used in absorption of acidic gases, catalyst for polyurethane foams, pH control agent.
Methyldiethanolamine is a reagent used for protection of boronic acids as N-methyl-O,O-diethanolamine esters.
Methyldiethanolamine is capable of undergoing reactions typical of both alcohols and amines, forming Quaternary amine salts, soaps, and esters.


This makes Methyldiethanolamine a useful intermediate in the synthesis of numerous products, and has resulted in its use in many diverse areas, including coatings, textile lubricants, polishes, detergents,pesticides, personal care products, and pharmaceuticals.
Methyldiethanolamine is widely used as a decarbonizer and Sweating agent in chemical, oil refinery, Gas synthesis, Natural gas & gas.


Methyldiethanolamine is more efficient absorber then MEA & DEA for sulphur contains impurity and acid gases found in natural gas processing.
Textiles : Methyldiethanolamine is used in manufacturing of softener, soap emulsifying agent, Lubricants, Paraffin Emulsion and dyes.
Pharmaceuticals: In synthesis of analgesics and the intermediate product for some products.


Gas absorbent : Purifies the gases particularly natural gas for the bulk removable of Carbon Dioxide and also used as a scrubbing and extracting agent in Gas treatment.
Catalyst : Effective catalyst for urethane and epoxy resin coating system.


Formulators : Methyldiethanolamine is used in lubricating oil, hydraulic fluids, corrosion inhibitor, refractory binder, surface active agent, solvent in water paint formula, Herbicides, Pesticides formulation and for PH control.
Methyldiethanolamine is used as an intermediate, to absorb acidic gases, as catalyst for polyurethane foams, and pH control agent.


Methyldiethanolamine is used in chemical syntheses (i.e. pharmaceuticals and cationic surfactants), as a cleaning-washing agent, pH regulator (coating manufacture), and solvent (removal of acid gases in oil refineries)
Methyldiethanolamine is used to make fine and large scale chemicals, as a catalyst in polymerization reactions, laboratory reagent, additive in coatings and concrete-cement, in gas treatment, and lubricants and metalworking fluids.


Methyldiethanolamine is permitted for use as an inert ingredient in non-food pesticide products;
Methyldiethanolamine is a new solvent with excellent performance for selective desulfurization and decarburization.
Methyldiethanolamine has the advantages of high selectivity, less solvent consumption, remarkable energy saving effect, and not easy to degrade.


Methyldiethanolamine is widely used in oil gas and gas desulfurization purification emulsifier and acid gas absorbent, acid-base control agent, polyurethane foam catalyst.
The carbon dioxide in synthetic ammonia can be removed with the participation of an activator, so that Methyldiethanolamine has been gradually promoted in the absorption of carbon dioxide in flue gas in recent years.


In addition, Methyldiethanolamine can also be used as pesticides, emulsifiers, semi-finished products of fabric additives, intermediates of antineoplastic drug hydrochloric acid nitrogen mustard, catalyst of carbamate coatings, it is also a drying accelerator for paint.
Methyldiethanolamine is mainly used as an emulsifier and an absorbent of acid gas, and is also used as an intermediate for antitumor drugs.


Methyldiethanolamine is used Pharmaceuticals, Water treatment, Fabric treatment, Coatings, and Gas treatment
Commercial Uses: Methyldiethanolamine is known by at least 93 different synonyms3 and has many commercial applications, including in the manufacture of construction and building materials, ink for inkjet printers, film forming, and as a component in fragrances.



BENEFITS OF METHYLDIETHANOLAMINE:
*Versatile
*Polyfunctional
*Combine characteristics of amines and alcohols



REACTIVITY PROFILE OF METHYLDIETHANOLAMINE:
Methyldiethanolamine is an aminoalcohol.
Amines are chemical bases.
They neutralize acids to form salts plus water.
These acid-base reactions are exothermic.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Methyldiethanolamine may react with oxidizing materials.



PREPARATION OF METHYLDIETHANOLAMINE:
N-methyldiethanolamine is produced by the reaction between ethylene oxide and methylamine.
Preparation of N-methyldiethanolamine



CHEMICAL PROPERTIES OF METHYLDIETHANOLAMINE:
Methyldiethanolamine is a colorless to yellow viscous liquid with an ammonia-like odor.
Methyldiethanolamine is completely soluble in water.
Methyldiethanolamine is an alkyl alkanolamine.
Methyldiethanolamine combines the chemical characteristics of both amines and alcohols so that it is capable of undergoing reactions typical of both alcohols and amines: forming quaternary amine salts, soaps, and esters.



PHYSICAL AND CHEMICAL PROPERTIES OF METHYLDIETHANOLAMINE:
*colorless or yellowish viscous liquid
*boiling point 246~248 ℃
*flash point 260 ℃
*freezing point -21 ℃
*latent heat of vaporization 519.16KJ/Kg
*boiling point 247 ℃
*water-soluble, soluble in water and alcohol, slightly soluble in ether



PHYSICAL and CHEMICAL PROPERTIES of METHYLDIETHANOLAMINE:
Molecular Weight: 119.16 g/mol
XLogP3-AA: -1.1
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 3
Rotatable Bond Count: 4
Exact Mass: 119.094628657 g/mol
Monoisotopic Mass: 119.094628657 g/mol
Topological Polar Surface Area: 43.7Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 43.7
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C5H13NO2
Molar mass: 119.164 g·mol−1

Appearance: Colorless liquid
Odor: Ammoniacal
Density: 1.038 g mL−1
Melting point: −21.00 °C; −5.80 °F; 252.15 K
Boiling point: 247.1 °C; 476.7 °F; 520.2 K
Solubility in water: Miscible
Vapor pressure: 1 Pa (at 20 °C)
Refractive index (nD): 1.4694
Viscosity: 101 mPa s (at 20°C)
Physical state: clear, viscous liquid
Color: light yellow
Odor: ammoniacal
Melting point/freezing point:
Melting point/range: -21,3 °C
Initial boiling point and boiling range: 246 - 248 °C - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 8,8 %(V)
Lower explosion limit: 1,4 %(V)
Flash point 127 °C - closed cup
Autoignition temperature: 280 °C at 1.013 hPa
Decomposition temperature: No data available
pH: 11,5 at 100 g/l at 20 °C

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 101 mPa.s at 20 °C
Water solubility: completely miscible
Partition coefficient: n-octanol/water: log Pow: -1,08
Vapor pressure: 0,01 hPa at 20 °C
Density: 1,038 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Dissociation constant: 8,52 at 25 °C
Relative vapor density: 4,11 - (Air = 1.0)
Distillation Range: 240oC – 260oC
Water Content: 0.5 % Max by wt
Specific gravity at 20/20o C: 1.038 - 1.044
Colour 50 APHA max
Freezing Point : -21oC
Refractive Index, n20D: 1.4694
Dynamic Viscosity, at 20oC, m Pas : 101
pH of 0.1N Aq.soln. : > 10
Melting Point: -21°C
Color: Colorless to Yellow
Density: 1.0380 g/mL
Boiling Point: 243°C
Flash Point: 138°C

Infrared Spectrum: Authentic
Assay Percent Range: 99% min. (GC)
Packaging: Glass bottle
Linear Formula: (HOCH2CH2)2NCH3
Refractive Index: 1.4675 to 1.4695
Beilstein: 04, 284
Specific Gravity: 1.038
Solubility Information:
Solubility aq. soln.: miscible.
Other solubilities: miscible with benzene,soluble in most organic solvents
(alcohol,esters,aceton and chlorinated hydrocarbons),soluble in diethylether and aliphatic hydrocarbons.
IUPAC Name: 2-[(2-hydroxyethyl)(methyl)amino]ethan-1-ol
Viscosity: 101 mPa.s (20°C)
Formula Weight: 119.16
Percent Purity: 99+%
Physical Form: Liquid
Chemical Name or Material: N-Methyldiethanolamine, 99+%
Melting point: -21 °C
Boiling point: 246-248 °C(lit.)
Density: 1.038 g/mL at 25 °C(lit.)
vapor density: 4 (vs air)
vapor pressure: 0.01 mm Hg ( 20 °C)
refractive index: n20/D 1.469(lit.)

Flash point: 260 °F
storage temp.: Store below +30°C.
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 14.41±0.10(Predicted)
form: Liquid
color: Clear colorless to light yellow
Odor: Ammonical
PH Range: 11.5 at 100 g/l at 20 °C
PH: 11.5 (100g/l, H2O, 20℃)
explosive limit: 0.9-8.4%(V)
Viscosity: 99.05mm2/s
Water Solubility: MISCIBLE
BRN: 1734441
Stability: Stable.
InChIKey: CRVGTESFCCXCTH-UHFFFAOYSA-N
LogP: -1.16 at 23℃
Chemical name (CAS): 2,2'-(methylimino)bisethanol
CAS number: 105-59-9
Structural formula:
H3C−N
CH2CH2OH
CH2CH2OH

Molecular formula: C5H13NO2
Molecular weight: 119.16
Density: 1.038–1.041 g/cm3 at 20°C
Boiling point: 247°C
Vapour pressure: 2.6 hPa at 40°C
Solubility: miscible with water, low molecular weight
alcohols, esters, acetone, benzene and
chlorinated hydrocarbons; not miscible
with diethylether or aliphatic hydrocarbons
Color: yellow, Clear, Colorless
Density: 1.04 g/cm3 @ 20 °C (68 °F)
Dynamic Viscosity: 34.78 mPa.s @ 40 °C (104 °F)
Flash Point: 116 °C (241 °F)
Kinematic Viscosity: 99.05 mm2/s @ 20 °C (68 °F)
Lower Explosion Limit: 0.9 %(V)
Melting Point: -21 °C (-6 °F)
Odor: ammoniacal, amine-like
Partition Coefficient:
Pow: 25 °C (77 °F) log Pow: -1.08 @ 25 °C (77 °F)
pH: 10.4 - 11.5 @ 20 - 25 °C (68 - 77 °F)
Relative Density: 1.041 @ 20 °C (68 °F) Reference Material: (water = 1)
Relative Vapor Density: 4 @ 20 - 25 °C (68 - 77 °F)

Solubility in Water: completely miscible
Upper Explosion Limit: 10 %(V)
Vapor Pressure: < 0.01 mmHg @ 20 °C (68 °F)
Molecular Formula: C5H13NO2
Molar Mass: 119.16
Density: 1.038g/mLat 25°C(lit.)
Melting Point: -21 °C
Boling Point: 246-248°C(lit.)
Flash Point: 260°F
Water Solubility: MISCIBLE
Vapor Presure: 0.01 mm Hg ( 20 °C)
Vapor Density: 4 (vs air)
Appearance: Liquid
Color: Clear colorless to light yellow
Odor: Ammonical
BRN: 1734441
pKa: 14.41±0.10(Predicted)
PH: 11.5 (100g/l, H2O, 20℃)
Storage Condition: Store below +30°C.
Stability: Stable.
Explosive Limit: 0.9-8.4%(V)
Refractive Index: n20/D 1.469(lit.)

ΔfG°: -171.64 kJ/mol
ΔfH°gas: -383.46 kJ/mol
ΔfusH°: 19.90 kJ/mol
ΔvapH°: 62.12 kJ/mol
log10WS: 0.99
logPoct/wat: -1.097
McVol: 103.030 ml/mol
Pc: 4160.00 kPa
Tboil: [520.20; 520.45]K
Tc: 667.49K
Tfus: [250.00; 252.15]K
Vc: 0.371 m3/kmol
Cp,gas [244.80; 289.41]: J/mol×K [510.60; 667.49]
Cp,liquid [273.00; 304.00]: J/mol×K [303.15; 353.15]
η [0.0041200; 0.1420200]: Pa×s [288.00; 373.15]
ΔvapH [71.50; 73.00]: kJ/mol [422.00; 455.00]
Pvap [2.48; 101.30]: kPa [409.69; 520.28]
n0: [1.46008; 1.46840] [293.15; 303.10]
ρl [936.81; 1048.00]: kg/m3 [283.15; 423.15]
csound,fluid [1490.40; 1598.80]: m/s [288.15; 323.15]
γ [0.04; 0.04]: N/m [288.15; 333.15]



FIRST AID MEASURES of METHYLDIETHANOLAMINE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLDIETHANOLAMINE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLDIETHANOLAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLDIETHANOLAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 60 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181) for vapours of organic compounds.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLDIETHANOLAMINE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of METHYLDIETHANOLAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
N-METHYLDIETHANOLAMINE
105-59-9
Methyldiethanolamine
Bis(hydroxyethyl)methylamine
2,2'-(Methylimino)diethanol
Methyl diethanolamine
Ethanol, 2,2'-(methylimino)bis-
N-Methylaminodiglycol
N-Methyliminodiethanol
591248-66-7
N-Methyl-2,2'-iminodiethanol
2,2'-Methyliminodiethanol
N-Methyldiethanolimine
2-[2-hydroxyethyl(methyl)amino]ethanol
USAF DO-52
N,N-Bis(2-hydroxyethyl)methylamine
Bis(2-hydroxyethyl)methylamine
Methylbis(2-hydroxyethyl)amine
Diethanolmethylamine
Methyliminodiethanol
Ethanol, 2,2'-(methylimino)di-
N-methyl diethanolamine
N,N-Di(2-hydroxyethyl)-N-methylamine
Bis(2-hydroxyethyl) methyl amine
NSC 11690
CCRIS 4843
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
EINECS 203-312-7
BRN 1734441
UNII-3IG3K131QJ
3IG3K131QJ
N-Methylimino-2,2'-diethanol
DTXSID8025591
2-[(2-hydroxyethyl)(methyl)amino]ethan-1-ol
HSDB 6804
NSC-11690
EC 203-312-7
4-04-00-01517 (Beilstein Handbook Reference)
Ethanol,2'-(methylimino)di-
Ethanol,2'-(methylimino)bis-
WLN: Q2N1 & 2Q
N-methyl-diethanolamine
Mdea (diol)
N-Methyldethanolamne
methyl diethanol amine
MDE (CHRIS Code)
n-methyl-diethanol amine
N-methyl diethanol-amine
AMINO ALCOHOL MDA
di(hydroxyethyl)methylamine
SCHEMBL17605
bis-(Hydroxyethyl)methylamine
N-Methyl-2,2-iminodiethanol
N-Methyldiethanolamine, 99%
DTXCID605591
METHYLDIETHANOLAMINE, N-
CHEMBL3185149
N-Methyldiethanolamine, >=99%
2,2'-(methylazanediyl)diethanol
Etanol, 2,2'-(metilimino) bis-
NSC11690
NSC49131
NSC51500
METHYL DIETHANOLAMINE [INCI]
Tox21_201199
LS-389
MFCD00002848
N-METHYLDIETHANOLAMINE [HSDB]
NSC-49131
NSC-51500
STL281951
N-(2-Hydroxyethyl)-N-methylethanolam
AKOS009031354
N,N-bis-(2-hydroxyethyl)-methylamine
n-methyl-n,n-bis(2-hydroxyethyl)amine
AT34020
2,2'-(METHYLIMINO)BIS(ETHANOL)
NCGC00248955-01
NCGC00258751-01
CAS-105-59-9
2-[(2-hydroxy-ethyl)methyl-amino]-ethanol
FT-0663293
M0505
2,2'-(METHYLAZANEDIYL)BIS(ETHAN-1-OL)
2-Hydroxy-1-[(2-hydroxyethyl)methylamino]-ethyl
Q252344
J-523676
N-Methyldiethanolamine 1000 microg/mL in Ammonium Hydroxide
InChI=1/C5H13NO2/c1-6(2-4-7)3-5-8/h7-8H,2-5H2,1H
2,2′-(Methylazanediyl)di(ethan-1-ol)
Bis(2-hydroxyethyl)(methyl)amine
2,2′-Methyliminodiethanol
N,N-Bis(2-hydroxyethyl)methylamine
MDEA
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
Bis(2-hydroxyethyl)methylamine
Diethanolmethylamine
Methylbis(2-hydroxyethyl)amine
Methyliminodiethanol
N-Methyldiethanolamine
N-Methylimino-2,2'-diethanol
N-Methyliminodiethanol
N,N-Bis(2-hydroxyethyl)methylamine
2,2'-(Methylimino)diethanol
N-Methyl-2,2-iminodiethanol
N-Methyl-2,2'-iminodiethanol
USAF DO-52
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
MDEA; N-Methylaminodiglycol
N-Methyldiethanolimine
Eve
MDEA (diol)
N-(2-Hydroxyethyl)-N-methylethanolam
N,N-Di(2-hydroxyethyl)-N-methylamine
NSC 11690
MDEA, N-Methyl diethanolamin
2,2’Methyliminodiethanol
N- methyl diethanolamine
Methyldiethanolamine
N,N-Bis(2-Hydroxy ethyl)methylamine
Methyldiethanolamin
MDEA
2,2'-(Methylimino)diethanol
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
Bis(2-hydroxyethyl) methyl amine
Bis(2-hydroxyethyl)methylamine
2,2'-Methyliminodiethanol
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
N-Methyldiethanolamine.
MDEA; 2,2'-(Methylimino)diethanol
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
Bis(2-hydroxyethyl) methyl amine
Bis(2-hydroxyethyl)methylamine
2,2'-Methyliminodiethanol
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
N-Methyldiethanolamine.
MDEA;METHYL DIETHANOLAMINE
Methyldiethanolamin
Methyliminodiethanol
FC MDEA
usafdo-52
USAF DO-52
Mdea (diol)
Diethanolmethylamine
N-Methyldiethanolami
2,2'-(Methylimino)diethanol
2-(N-2-Hydroxyethyl-N-methylamino)ethanol
Bis(2-hydroxyethyl) methyl amine
Bis(2-hydroxyethyl)methylamine
Ethanol, 2,2'-(methylimino)bis-
MDEA
Methylbis(2-hydroxyethyl)amine
N,N-Bis(2-hydroxyethyl)methylamine
N,N-Di(2-hydroxyethyl)-N-methylamine
N-Methyl-2,2'-iminodiethanol
N-Methylaminodiglycol
N-Methyldiethanolimine; N-Methyliminodiethanol
2,2'-Methyliminodiethanol
Ethanol, 2,2'-(methylimino)bis-
Ethanol, 2,2'-(methylimino)di-
Methyl diethanolamine
2,2`-(Methylimino)bis-ethanol
Diethanolmethylamine
EVE; MDEA (diol)
Methyldiethanolamine
Methyliminodiethanol
N-(2-hydroxyethyl)-N-methylethanolamine
N-Methylbis(2-hydroxyethyl)amine
Amietol M12
Methyldiethanolamin
2,2-(Methylimino)Diethanol
2,2-Methyliminodiethanol
N-Methylediethanolamine
N-Methyl Diethanolamine
Methyl Diethanlamine
2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium
MDEA
N,N-Bis(2-Hydroxyethyl)Methylamine
MDEA
Methyl Diethanlamine
METHYL DIETHANOLAMINE
N-METHYLDIETHANOLAMINE
N-Methyldiethanolamine
N-Methyl Diethanolamine
N-Methylediethanolamine
2,2-Methyliminodiethanol
2,2-(Methylimino)Diethanol
N-METHYL-2,2'-IMINODIETHANOL
BIS(2-HYDROXYETHYL)METHYLAMINE
N-METHYL-2,2-IMINOBIS(ETHANOL)
N,N-BIS(2-HYDROXYETHYL)METHYLAMINE
N-METHYL-N-(2-HYDROXYETHYL)-2-AMINOETHANOL
2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium

Chemical Characterization Diethylene glycol monomethyl ether 2-(2-Methoxyethoxy)-ethanol CAS-No.: 111-77-3 EINECS-No.: 203-906-6 Product Description Methyl diglycol is a colorless, neutral, weakly hygroscopic and liquid with a mild pleasant odor. It is miscible in any ratio with water and the usual organic solvents e.g. acetone, diethyl ether and methanol. Methyl diglycol is starting material for the production of methyl diglycol acetate. It is also used as a solvent for fats, oils and waxes; constituent of hydraulic fluids; additive in cleaners for soiled surfaces and starting material for syntheses. To prevent dermal exposure methyl diglycol is not suitable for any application in paints and paint strippers. The technical characteristics of methyl diglycol enable it to meet the requirements stipulated for the technical Supply Conditions as drawn up in accordance with MIL-DTL-85470B in addition with an antioxidant (Clariant product name: Methyl diglycol JFA). Storage Advices Glycol ethers and their derivatives tend to form peroxides in the presence of air or oxygen. For further informations please refer to the safety data sheet. Storage tanks should be made from norm-steel or stainless steel. Aluminum and other light metals are not suitable due to alcoholate formation with methyl diglycol. Azeotropic mixtures Methyl diglycol builds no azeotrope with water and diglycol; nevertheless with several other organic solvents. Some of them are listed here: Methyl diglycol (in %)-Azeotrope with-in %-b.p. (°C) (at 1013 mbar) 80-acetophenone-20-191,90 46-amylether-54-179,50 49-dimethylaniline-51-184,85 33-dipentene-67-168,50 70-glycol-30-192,00 23-isoamylether-77-168,85 13-mesitylene-87-162,50 89-naphtaline-11-192,20 52-o-cresol-48-201,50 61-phenol-39-199,65 45-phenylacetate-55-188,60 30-p-cresol-70-208,00 Technical Data METYLDIGLYCOL molar mass-g/mol-120,2 METYLDIGLYCOL solidification point (DIN 51583) °C -65 METYLDIGLYCOL boiling range/1013 hPa °C 190-196 METYLDIGLYCOL flash point(DIN 51755) °C 91 METYLDIGLYCOL ignition temperature (DIN 51794) °C 245 METYLDIGLYCOL density/20°C (DIN 51757) g/cm³ 1,018-1,022 METYLDIGLYCOL kinematic viscosity/20°C (DIN 51562) mm²/s 3,9 METYLDIGLYCOL vapor pressure/20°C mbar 0,3 METYLDIGLYCOL heat of evaporation /1013 hPa kJ/kg 396 METYLDIGLYCOL evaporation number (DIN 53170, Diethylether = 1) ca. 900 METYLDIGLYCOL refractive number nD20 (DIN 51423, part 2) 1,4263 METYLDIGLYCOL surface tension/25°C mN/m 28,5 METYLDIGLYCOL dielectric constant/20°C (DIN 53483) 15,8 METYLDIGLYCOL specific heat /20°C kJ/kgK 2,15 METYLDIGLYCOL thermal conductivity /20°C W/mK 0,18 METYLDIGLYCOL critical density g/cm3 0,322 METYLDIGLYCOL critical temperature °C 357,1 METYLDIGLYCOL critical pressure bar 35,4 METYLDIGLYCOL miscibility with water miscible

METHYL GLUCETH-20, N° CAS : 68239-42-9 - Méthyle Gluceth-20, Origine(s) : Synthétique, Nom INCI : METHYL GLUCETH-20. Le méthyle Gluceth-20 est produit à partir de glucose, d'alcool méthylique et de dérivés de sucre. Il est utilisé en cosmétique en tant qu'émollient (adoucit la peau), humectant (retient l'eau) et hydratant. Il est employé principalement dans les soins hydratants et nourrissants pour des peaux plutôt sèches et irritées.Ses fonctions (INCI): Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Hydratant : Augmente la teneur en eau de la peau et aide à la maintenir douce et lisse

METHYLENE BIS MORPHOLINE; N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine cas no: 5625-90-1

N,N'-Methylenebisacrylamide; N-[(Prop-2-enoylamino)methyl]prop-2-enamide cas no: 110-26-9

N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine CAS:5625-90-1

N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine CAS:5625-90-1

Dichloromethane; Freon 30; Methylene dichloride; Chlorure De Methylene; Chlorocarbon; Methylene Bichloride; Metylenu Chlorek CAS NO:75-09-2

Methylenephosphonic Acid; Bis Hexamethylenetriaminepenta(Methylenephosphonic Acid); TPMP; DTMPA; DETA-Phos; [[(phosphonomethyl)imino]bis[2,1-ethanediylnitrilobis(methylene)]]tetrakis- Phosphonic acid; CAS NO: 15827-60-8

N,N'-Methylene-bis-morpholine helps to increase the life of metalworking fluid with maintaining the stable product function and preserving the fluid from bacteria and fungi. It could be for metalworking fluid concentrate during manufacturing or for tank side treatment. Name: N,N'-Methylene-bis-morpholine CAS: 5625-90-1 N,N'-Methylene-bis-morpholine - CAS 5625-90-1 Molecular Formula: C9H18N2O2 Molecular Weight: 186.251 Name N,N'-Methylene-bis-morpholine Synonyms N,N-Dimorpholinomethane Morpholine,4,4-methylenebis- Bis(4-morpholinyl)methane N,N'-Methylenebismorpholine 4,4'-methanediyldimorpholine 4,4-methylenebis-Morpholine CAS 5625-90-1 EINECS 227-062-3 N,N'-Methylene-bis-morpholine - Physico-chemical Properties Molecular Formula C9H18N2O2 Molar Mass 186.251 g/mol Density 1.09g/cm3 Boling Point 265.1°C at 760 mmHg Flash Point 77.6°C Vapor Presure 0.00935mmHg at 25°C Refractive Index 1.496 1.Product name:N,N'-Methylene-bis-morpholine 2.Molecular weight:186.25 Molecular formula:C9H18N2O2 3.CAS No:5625-90-1 Eiencs No:227-062-3 4.Specification Item Index Purity of Active Content >92% Appearance Colorless liquid Density 1.08-1.10g/m³ Boiling point ℃ 122-124(P=12torr) PH(1% water) 9.0-11.0 Solubility in Water Completely Usage of MBM ( Methylene-bis-morpholine) : 1, a low toxicity broad spectrum fungicide for water-based metalworking fluid 2, anti-Bacteria and fungi effectively 3, fully meet with the requirements of water-based metalworking fluid: low skin irritation, mild odor, low toxicity; formulation compatibility, lasting bactericidal. At higher concentrations, fungi and molds also have better inhibition.Recommended addition amount (mass ratio): Recipe 2-3%, the working liquid 1-2‰; 6.Package: 25kg/ drums or 200kg/ drums Application and Benefits of Methylene-bis-morpholine : Biocide ( Preservative ) in the the metal working fluid composition permits the efficient practice of cutting, grinding, form rolling, press working and plastic working of metallic materials. In addition, the fluid composition is excellent in the antiseptic properties and it is seldom that the fluid composition adversely affects the environment of the earth and the human bodies. The fluid composition comprises a morpholine compound,the fluid composition is significantly improved in the antiseptic properties and the service life of the metal working fluid composition can thus significantly be extended, as compared with conventionally known metal working fluid compositions. As a result, the fluid composition would permit the saving of natural resources, and the reduction of the amount of waste matter (waste fluid) and accordingly, the use thereof would result in the reduction of any adverse effect on the environment of the earth. NO MORE FORMALDEHYDE !! Formaldehyde occurs naturally in the environment as a by-product of metabolic processes in humans, animals and through the natural decay process of plant species. Formaldehyde is even detectable in human breath at low levels. Under the changes planned to the labelling of certain chemicals, formalin-releasing species have been re-classified according to their total potential to release formaldehyde and not through actual measurement in use. Research by several chemical manufacturers supports very low levels, no higher than the surrounding environment, when used well managed metalworking fluid systems. Formaldehyde has long been classed as a category 1B carcinogen. Formaldehyde Depots or ‘donors’ (FADs) have been used to improve the sump life of soluble metalworking fluids. New legislation now affects certain formalin- containing biocides. Under the recent update to CLP regulation, ATP (Adaptation to Technical Progress, review May 4th 2017), any product or treated article which contains certain formalin-containing biocides (to protect the function of the product) will need to be labelled as category 1B. Examples of the biocides affected include methylene bis-morpholine (MBM) and methylene bis[5-methyloxazolidine] (MBO). Methylene bis-morpholine (MBM) is a low toxicity biocide developed for use in metal working concentrates. Nipacide MBM is effective against a wide range of microorganisms including gram positive and gram negative bacteria, yeast and fungi. Microorganisms grow at a rapid rate and without use of the correct biocide, numbers can increase dramatically. Methylene bis-morpholine (MBM)is recommended for preservation of metal working solution concentrates. N,N'-Methylene-bis-morpholine is effective against a wide range of spoilage organisms and effective over a wide pH and temperature range. Use level; Methylene bis morpholine should be evaluated in finished products at levels between 2.0% and 5.0%.

Trisodium dicarboxymethyl alaninate; * N,N-Bis(carboxymethyl)-DL-alanin trisodium salt; N-(1-Carboxyethyl)-iminodiacetic acid; α-Alanindiacetic acid; α-ADA; MGDA-Na3; Trilon M; carboxylatoethyl)iminodiacetate, methylglycinediacetic acid trisodium salt (MGDA-Na3) or trisodium α-DL-alanine diacetate (α-ADA), cas no: 164462-16-2

Methylglucose dioleate is a versatile cosmetic ingredient derived from natural sources.
Its polyethylene glycol ether composition makes it effective as a surfactant in various cosmetic products.
Methylglucose dioleate acts as a potent thickener, adding a luxurious texture to skincare formulations.
Emulsifying properties enable it to create stable and visually appealing cosmetic emulsions.



APPLICATIONS


Some applications of Methylglucose dioleate include:

Surfactant:
Methylglucose dioleate acts as a surfactant, enabling it to reduce the surface tension between different substances.
Methylglucose dioleate helps in mixing oil and water-based ingredients, creating stable and uniform cosmetic formulations.

Thickener:
Methylglucose dioleate functions as a thickening agent in various cosmetic products, such as creams, lotions, and gels.
Methylglucose dioleate imparts a luxurious and smooth texture to the products, enhancing their application and skin feel.

Emulsifier:
Methylglucose dioleate is an effective emulsifier, allowing the formation of stable oil-in-water emulsions.
This property is particularly valuable in creating emulsified skincare products like creams and lotions.

Skin Irritation Reduction:
Due to its gentle and non-irritating nature, cosmetics containing Methylglucose dioleate can be used in formulations targeted for sensitive skin or products designed to minimize skin irritation.

Moisturizer:
Methylglucose dioleate's ability to form a protective barrier on the skin's surface helps retain moisture, making it a suitable ingredient for moisturizing products.

Eco-friendly and Natural Cosmetics:
Methylglucose dioleate's derivation from natural Methylglucose and Oleic Acid aligns with the growing demand for eco-friendly and naturally derived cosmetic ingredients.

Hypoallergenic Formulations:
Its low potential for causing skin irritation makes it a favored choice in hypoallergenic cosmetic formulations.

Baby Care Products:
Methylglucose dioleate's gentle and non-irritating properties make it a suitable ingredient in baby care products like lotions and creams.

Haircare Products:
Methylglucose dioleate can be used in haircare products to provide conditioning and moisturizing effects, maintaining a balanced moisture level in the hair.

Clean Beauty Standards:
Methylglucose dioleate's natural origin and safe profile align with the principles of clean beauty, appealing to consumers seeking safer and more natural cosmetic options.

Sunscreens:
Methylglucose dioleate can be included in sunscreen formulations to enhance their texture and provide moisturizing benefits.

Makeup Products:
Methylglucose dioleate can be found in various makeup products, such as foundations and concealers, to improve their spreadability and skin feel.

Pharmaceutical Formulations:
Given its non-irritating and skin-friendly nature, Methylglucose dioleate might find applications in pharmaceutical formulations, such as topical creams or ointments.

Drug Delivery Systems:
Its emulsifying properties could potentially be utilized in the development of drug delivery systems, allowing for controlled and targeted release of active pharmaceutical ingredients.

Food Industry:
As an emulsifier and thickener, Methylglucose dioleate could be explored for use in food products, enhancing texture and stability in certain formulations.

Agrochemicals:
The surfactant properties of the compound might have applications in the formulation of agrochemicals, such as herbicides or insecticides.

Industrial Applications:
Methylglucose dioleate could be considered for various industrial applications, such as in lubricants or metalworking fluids due to its emulsification and stabilizing abilities.

Cleaning Products:
Its surfactant properties may make it suitable for use in household or industrial cleaning products to enhance their cleaning efficiency.

Textile Industry:
As a thickener and emulsifier, it could potentially be used in textile applications, such as fabric softeners or specialty finishes.

Paints and Coatings:
Its emulsifying properties might find applications in water-based paints and coatings.


Methylglucose dioleate is widely utilized as a surfactant in various cosmetic formulations, such as cleansers and shampoos.
Its excellent emulsifying properties make it a key ingredient in the production of stable creams and lotions.
Methylglucose dioleate's thickening ability adds a luxurious texture to moisturizers and body butters.

Due to its gentle nature, Methylglucose dioleate is often incorporated into products intended for sensitive and delicate skin, like baby lotions.
Methylglucose dioleate acts as a co-emulsifier in sunscreens, aiding in the uniform distribution of UV filters and enhancing their water-resistance.

In haircare products like conditioners, it helps in detangling and providing smoothness to the hair.
Methylglucose dioleate is used as an emulsifier in foundation formulations, allowing even dispersion of pigments for a smooth application.

Methylglucose dioleate contributes to the creamy texture of lipsticks and lip balms.
Its emulsifying properties extend to body washes and shower gels, creating stable and visually appealing formulations.

As an essential ingredient in bath oils, Methylglucose dioleate ensures the even dispersion of oils in water, enhancing the bathing experience.
Methylglucose dioleate is incorporated into hand creams and moisturizing gloves for its skin-soothing benefits.
Methylglucose dioleate is utilized in facial masks to stabilize the mixture and promote even application on the skin.

Methylglucose dioleate's thickening properties are utilized in hair styling products like gels and mousses.
Methylglucose dioleate acts as an effective emulsifier in makeup removers, enabling the removal of stubborn cosmetics.
Methylglucose dioleate can be found in anti-aging skincare products, helping to disperse active ingredients that promote skin elasticity and hydration.
Methylglucose dioleate's emulsification capabilities are harnessed in body scrubs and exfoliants, combining oil and exfoliating particles.
In baby wipes, Methylglucose dioleate plays a role in evenly distributing cleansing agents while maintaining gentleness.

Methylglucose dioleate can be used in sunless tanning products to ensure an even application of the tanning agent.
Methylglucose dioleate finds application in massage oils, providing a smooth glide and preventing greasiness.
Methylglucose dioleate is employed in moisturizing face masks, improving the product's consistency and hydration benefits.

In post-shave lotions, Methylglucose dioleate aids in soothing the skin while keeping the formulation stable.
Methylglucose dioleate's thickening properties extend to body creams and body soufflés.
Methylglucose dioleate is included in cosmetic serums to enhance the absorption of active ingredients into the skin.

Methylglucose dioleate can be used in waterproof makeup products, ensuring their long-lasting properties.
Methylglucose dioleate's emulsifying capabilities make it useful in natural and organic cosmetic products, adhering to clean beauty principles.



DESCRIPTION


Methylglucose dioleate is a versatile cosmetic ingredient derived from natural sources.
Its polyethylene glycol ether composition makes it effective as a surfactant in various cosmetic products.
Methylglucose dioleate acts as a potent thickener, adding a luxurious texture to skincare formulations.
Emulsifying properties enable it to create stable and visually appealing cosmetic emulsions.

Methylglucose dioleate's gentle nature reduces irritation, making it suitable for sensitive skin types.
Cosmetics featuring this compound provide a soothing and comfortable experience to users.
Its unique molecular structure gives it a high molecular weight, preventing deep skin penetration.

As a result, Methylglucose dioleate forms a protective barrier on the skin's surface, locking in moisture.
Methylglucose dioleate enhances the overall stability and shelf life of cosmetic products.

Methylglucose dioleate imparts a smooth and velvety feel to cosmetic formulations, leaving the skin soft and supple.
Due to its non-greasy nature, Methylglucose dioleate is well-suited for a wide range of skincare and haircare products.
Methylglucose dioleate is known for its compatibility with various active ingredients in cosmetic formulations.

Its eco-friendly and sustainable origin aligns with the growing demand for natural cosmetics.
Cosmetics containing this compound are favored for their mildness and non-comedogenic properties.

Methylglucose dioleate plays a vital role in creating well-balanced and stable oil-in-water emulsions.
The compound's excellent dispersing ability ensures even distribution of ingredients in cosmetic products.
Its low potential for skin irritation makes it a popular choice in hypoallergenic formulations.
Methylglucose dioleate's viscosity-enhancing capabilities lend a luxurious feel to creams and lotions.

Methylglucose dioleate contributes to the elegant appearance and texture of cosmetic products during application.
As an effective emollient, Methylglucose dioleate leaves the skin feeling moisturized and conditioned.
Methylglucose dioleate's natural origin and safe profile align with clean beauty standards.

Methylglucose dioleate is a preferred ingredient in baby care products for its gentle and soothing properties.
When used in haircare products, Methylglucose dioleate aids in maintaining a balanced moisture level in the hair.
The surfactant properties allow Methylglucose dioleate to create gentle yet effective cleansing products.
Methylglucose dioleate exemplifies the innovation in cosmetic science, catering to consumers seeking effective yet skin-friendly formulations.



FIRST AID


Skin Exposure:

Remove contaminated clothing and accessories immediately.
Wash the affected skin area gently but thoroughly with plenty of soap and water.
Rinse the skin with water for at least 15 minutes to ensure complete removal of the chemical.
If skin irritation, redness, or other adverse reactions occur, seek medical attention promptly.
Avoid using any chemical solvents or substances to remove the chemical from the skin, as they may exacerbate the situation.


Eye Exposure:

Flush the affected eye(s) with clean water or saline solution immediately. Use an eye wash station if available.
Hold the eye open while flushing to ensure thorough rinsing of the eye surface.
Continue flushing the eye(s) for at least 15 minutes or until medical help arrives.
Do not rub or put pressure on the eyes as it may worsen any potential damage.
Seek immediate medical attention or contact an ophthalmologist if eye irritation, pain, or vision problems persist.


Inhalation:

If there is accidental inhalation of any unknown substance or chemical, immediately move to an area with fresh air.
If the person exposed to the chemical is experiencing difficulty breathing or any respiratory distress, seek immediate medical attention or call emergency services.


Ingestion:

If the substance is ingested accidentally, do not induce vomiting unless directed to do so by a healthcare professional or poison control center.
Rinse the mouth thoroughly with water if the chemical was swallowed accidentally.
Seek immediate medical attention or contact a poison control center for further guidance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including safety goggles, chemical-resistant gloves, lab coat or protective clothing, and closed-toe shoes when handling any chemicals.

Ventilation:
Work in a well-ventilated area or use fume hoods or local exhaust ventilation systems to minimize exposure to chemical vapors and fumes.

Avoid Direct Contact:
Avoid direct skin contact with the chemical.
If contact occurs, promptly wash the affected area with soap and water.

Mixing and Dilution:
Follow specific instructions for mixing or diluting the chemical.
Always add chemicals to water slowly, not the other way around, to prevent splashes or releases of energy.

Labeling:
Keep containers properly labeled with the correct chemical name, concentration, hazard symbols, and any other relevant information.

Containment:
Use appropriate containers and storage units to prevent spills and leaks.
Secondary containment measures may be necessary for hazardous materials.

Transfer with Care:
Use appropriate tools and equipment to transfer the chemical safely.
Avoid transferring chemicals by mouth or using equipment not meant for that purpose.

No Eating, Drinking, or Smoking:
Prohibit eating, drinking, or smoking in areas where chemicals are handled to avoid accidental ingestion.


Storage:

Compatibility:
Store chemicals based on compatibility to prevent any undesirable reactions or hazards.
Segregate incompatible substances.

Temperature:
Store chemicals at the recommended temperature range specified in the SDS or as indicated by the supplier.

Light Exposure:
Some chemicals may be light-sensitive.
Store light-sensitive substances in opaque containers or away from direct light.

Moisture:
Protect chemicals from moisture by keeping containers tightly sealed and stored in dry conditions.

Secure Storage:
Store chemicals in a dedicated chemical storage area with limited access to authorized personnel only.

Ventilation:
Ensure the storage area is well-ventilated to prevent the buildup of vapors or fumes.

Shelving and Stability:
Use appropriate shelving and ensure that chemicals are stable and not at risk of falling or collapsing.

Emergency Equipment:
Keep emergency response equipment, such as spill kits and eyewash stations, readily available in the storage area.

Separate from Food and Pharmaceuticals:
Store chemicals separately from food, beverages, pharmaceuticals, and other items not intended for chemical use.



SYNONYMS


Methyl Glucose Oleate Ether
Polyethylene Glycol Ether of Methylglucose Oleate
Methyl Glucose Dioleoyl Ether
Methyl Glucose Oleate Diether
PEG Ether of Methylglucose Oleate
Methyl Glucose Oleate Diester Polyethylene Glycol Ether
Methylglucose Oleate PEG Diester
Methylglucose Oleic Acid Diester PEG Ether
Methylglucose Dioleic Acid Polyethylene Glycol Ether
Methylglucose Dioléate d'Oleic Acid
Oleic Acid Methyl Glucose Diester Ethoxylate
Methyl Glucose Di-Oleate Ethylene Glycol Ether
Oleoyl Methyl Glucose Ether
Methyl Glucose Dioléate PEG Esters
Methyl Glucose Oleyl Ether
Ethoxylated Methyl Glucose Oleate
Methyl Glucose Oleic Acid Ester PEG Ether
Polyethylene Glycol Ether of Methylglucose Dioléate
Methyl Glucose Dioleate Ethoxylate
Methyl Glucose Oleate PEG Diether
Ethylene Glycol Ether of Methylglucose Dioleate
Oleic Acid Methyl Glucose Diol Ether
Methyl Glucose Oleic Acid Diester Ethoxylate
Methyl Glucose Oleic Acid PEG Ester
Methyl Glucose Oleyl Alcohol Diester PEG Ether
Oleic Acid Methyl Glucose Polyethylene Glycol Ether
Methyl Glucose Oleoyl Polyethylene Glycol Ether
Methyl Glucose Oleate Diol PEG Ether
Ethylene Glycol Methyl Glucose Dioléate
Methyl Glucose Oleyl Diester Ethoxylate
Methyl Glucose Dioleate Ethylene Glycol Ester
Oleic Acid Methyl Glucose Oleyl Ether
Methyl Glucose Oleate Diol Polyethylene Glycol Ether
Methylglucose Oleic Acid Diol Ether PEG
Methyl Glucose Dioléate Oleic Acid Ethoxylate
Oleic Acid Methyl Glucose PEG Diether
Ethylene Glycol Ether of Methyl Glucose Oleate
Methyl Glucose Oleyl Polyethylene Glycol Diether
Methyl Glucose Oleic Acid Diester Ethylene Glycol Ether
Methyl Glucose Dioleyl Polyethylene Glycol Ether
Ethoxylated Methyl Glucose Oleic Acid Ester
Methyl Glucose Oleate Ethoxylate Diol
Oleic Acid Methyl Glucose Diether Ethylene Glycol
Methyl Glucose Oleyl Acid Diol PEG Ether
Methyl Glucose Oleic Acid Polyethylene Glycol Diether
Ethylene Glycol Ether of Methyl Glucose Dioleate
Methyl Glucose Oleate Ethoxylated Diol
Methyl Glucose Oleic Acid Diester PEG Esters
Methyl Glucose Dioleic Acid Polyethylene Glycol Ester
Oleic Acid Methyl Glucose Diol Ether PEG
Methyl Glucose Oleate PEG Dioléate
Methyl Glucose Oleyl Diester Ethylene Glycol Ether
Ethylene Glycol Methyl Glucose Oleate Diester
Methyl Glucose Oleic Acid Ethoxylated Diol
Methyl Glucose Dioleate Ethoxylated Oleic Acid
Methyl Glucose Oleic Acid Diol PEG Ether
Oleic Acid Methyl Glucose Diol Polyethylene Glycol Ester

Synonyms: D,L-methylglycinediacetic acid trisodium salt; Trisodium 2-Methylnitrilotriacetate Hydrate; methylglycine-N,N-diacetic CAS No.: 164462-16-2

Chemical Characterization Ethylene glycol monomethylether 1-Hydroxy-2-methoxyethane 2-Methoxyethanol CAS-No.: 109-86-4 EINECS-No.: 203-713-7 Registrations: EINECS (Europe), TSCA (USA), AICS (Australian),DSL (Canada), ECL (Korea), PICCS (Philippines), ENCS (Japan),ASIA-PAC Product Description Methyl glycol is a colorless, neutral, weakly liquid with a mild pleasant odor. It is miscible in any ratio with water and the usual organic solvents (except for saturated hydrocarbons, e. g. special boiling point petroleum spirits).Methyl glycol enters into the typical alcohol reactions like esterification, etherification, oxidation, acetal and alcoholate formation. Therefore it is used as a starting material for syntheses of organic intermediates. Methyl glycol is also used as an antifreeze in aviation fuels for jet aircrafts (about 0.10 - 0.15 % by volume, relative to the fuel). The technical characteristics of methyl glycol enable it to meet the requirements stipulated for the technical Supply Conditions as drawn up in accordance with MIL-DTL-2786G (NATO-Code-Number: S-748) in addition with an antioxidant. Storage Advices Glycol ethers and their derivatives tend to form peroxides in the presence of air or oxygen. To prevent the formation of peroxides the product should be stored under an inert nitrogen atmosphere. Despite the very mild odor of methyl glycol, the general precautionary measures for the handling of solvents must always be observed. For further informations please refer to the safety datasheet. Storage tanks should be made from norm-steel or stainless steel. Aluminium and other light metals are not suitable due to alcoholate formation with methyl glycol. We found the following materials suitable. Technical Data Methyl glycol molar mass g/mol 76,1 Methyl glycol solidification point (DIN 51583) °C -85 Methyl glycol boiling range/1013 hPa °C 123-126 Methyl glycol flash point(DIN 51755) °C 37 Methyl glycol ignition temperature (DIN 51794) °C 325 Methyl glycol density/20°C (DIN 51757) g/cm³ 0,967 Methyl glycol vapor density (Luft = 1) 2,63 Methyl glycol vapor pressure/20°C mbar 8,1 Methyl glycol kinematic viscosity/20°C (DIN 51562) mm²/s 1,71 Methyl glycol dielectric constant/20°C (DIN 53483) 16,9 Methyl glycol critical density g/cm3 0,313 Methyl glycol critical temperature °C 292,2 Methyl glycol critical pressure bar 50,1 Methyl glycol dipole moment/25°C Debye 2,04 Methyl glycol surface tension/25°C mN/m 31,2 Methyl glycol refractive number nD20 (DIN 51423, part 2) 1,402 Methyl glycol heat of evaporation /1013 hPa kJ/kg 519 Methyl glycol evaporation number (DIN 53170, Diethylether = 1) 34 Methyl glycol thermal conductivity /20°C W/mK 0,19 Methyl glycol specific heat /20°C kJ/kg*K 2,30

Methylhydroxyethyl cellulose, also known as Hydroxyethyl Methyl Cellulose (HEMC)e, is a non-ionic cellulose ether.
Methylhydroxyethyl cellulose is made from natural polymer cellulose through a series of etherification reactions.
Methylhydroxyethyl cellulose is a white, powder.


CAS Number: 9032-42-2
Chem/IUPAC Name: Cellulose methyl ether, 2-hydroxyethyl ether
Chemical formula: variable


Methylhydroxyethyl cellulose is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Methylhydroxyethyl cellulose’s a cellulose ether which is based on methyl cellulose.


Compared to other cellulose ether chemistries, the methylcellulose derivatives have a slightly more Newtonian flow characteristic which provides increased high-shear (ICI) viscosity.
Methylhydroxyethyl cellulose has a good stability even though in alkaline environment and provide a good stability in heat environment.


Methylhydroxyethyl cellulose provides viscosity, which can be used as an anti – precipitation agent.
Methylhydroxyethyl cellulose may contain further additives which for example control the dissolution behavior or the thickening power.
Methyl Hydroxyethyl Cellulose (MHEC), in the form of a powder, is a thickening agent.


Methylhydroxyethyl cellulose is more resistant to saline, easily soluble in water and has higher gel temperature. Methylhydroxyethyl cellulose is also known as HEMC, Methyl Hydroxyethyl Cellulose, which can be used as highly efficient water retention agent, stabilizer, adhesives and film-forming agent in construct.


Methylhydroxyethyl cellulose is a modified hydroxyethyl methylcellulose with delayed solubility.
Methylhydroxyethyl cellulose is also called as Hydroxyethyl Methyl Cellulose HEMC.
Methylhydroxyethyl cellulose is a non-ionic cellulose ether made from natural high polymer cellulose.


The properties of Methylhydroxyethyl cellulose and methylcellulose are similar, but the presence of hydroxyethyl makes Methylhydroxyethyl cellulose cellulose more soluble in water, the solution is more compatible with salt and has a higher aggregation temperature.
Methylhydroxyethyl cellulose is also called hypromellose.


Methylhydroxyethyl cellulose is a white, yellow-white or off-white powder or granules, hygroscopic after drying.
Methylhydroxyethyl cellulose is a methylcellulose based cellulose.
Methylhydroxyethyl cellulose's pH value exists between 5.0 and 8.0.


Methylhydroxyethyl cellulose is water soluble nonionic cellulose ethers, which are offered as free flowing powder or in granular form cellulose.
Methylhydroxyethyl cellulose is considered to be non-toxic.
Methylhydroxyethyl cellulose can be described as a modified cellulose polymer consisting of methyl, ethyl, and hydroxyethyl side chains.


Methylhydroxyethyl cellulose is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.
Methylhydroxyethyl cellulose excels in water retention and improves adhesion.
Methylhydroxyethyl cellulose dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.


Methylhydroxyethyl cellulose is a white, odorless powder.
Methylhydroxyethyl cellulose is a water soluble.
Methylhydroxyethyl cellulose is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.


Methylhydroxyethyl cellulose is a non-ionic cellulose ether made from natural high polymer cellulose.
Methylhydroxyethyl cellulose is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.


Methylhydroxyethyl cellulose is a kind of odorless, tasteless, non-toxic white powder or granule.
Methylhydroxyethyl cellulose offers many of the same advantages as other methyl cellulose derivatives, such as effective thickening and moisture retention.
Methylhydroxyethyl cellulose has great film formation in construction projects.


Methylhydroxyethyl cellulose is a non-ionic cellulose ether that widely used in construction materials.
Methylhydroxyethyl cellulose could be dissolved in hot or cold water to form a transparent solution with a particular viscosity.
Methylhydroxyethyl cellulose is a safe, strong, and resistant product you can depend on.


Methylhydroxyethyl cellulose is medium-high viscosity construction grade Methyl Hydroxyethyl Cellulose widely used in building materials.
Methylhydroxyethyl cellulose could be soluble in water to form a transparent solution
Methylhydroxyethyl cellulose is a gelling and thickening agent that is derived from cellulose.


The chemical formula of this compound is variable because the number of unit structures per Methylhydroxyethyl cellulose molecule can vary.
Methylhydroxyethyl cellulose stands for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.


Methylhydroxyethyl cellulose is a gelling and thickening agent derived from cellulose.
Methylhydroxyethyl cellulose, also known as Methylcellulose and colloquium, is an organic compound uses in various cosmetic and medical applications, the primary one being as a thickening agent.


Methylhydroxyethyl cellulose is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Methylhydroxyethyl cellulose appears to be white powder and is odorless and tasteless.


Methylhydroxyethyl cellulose could dissolve in water and form a clear solution with specific viscosity.
Also called MHEC, it is short-term for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose's produced from a natural renewable polymer, wood pulp, or refined cotton.


The cold water disperses the model product, can make the mix more quick and convenient, and does not produce the mass.
Generate favorable flow characteristics, including low spatter and good leveling, to ensure fine surface finish and prevent the flow of paint.
In cold water Methylhydroxyethyl cellulose will swell into colloidal solution and its solubility is not influenced by PH value.


Similar to methyl cellulose while being added to Hydroxyethyl groups.
Methylhydroxyethyl cellulose is water soluble, nonionic cellulose ethers, which are offered as free flowing powder or in granular form.
Methylhydroxyethyl cellulose can be used in water-based latex paints and printing inks.


Methylhydroxyethyl cellulose is a non-ionic cellulose ether that evolved from the addition of ethylene oxide to methylcellulose.
Methylhydroxyethyl cellulose is ether of cellulose and ethylene oxide mainly used as adhesive protective gelatin, thicker agent and stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets.


Methylhydroxyethyl cellulose can be white to off-white powder, but it's odorless regardless of color, safe for all animal species, and environmentally friendly.
Methylhydroxyethyl cellulose is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.


Methylhydroxyethyl cellulose is nonionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
Methylhydroxyethyl cellulose enhances the liquidity and pumpability, thus improving the efficiency of the flooring.
The term HPMC stands for hydroxypropyl methyl cellulose, while the term Methylhydroxyethyl cellulose stands for methyl hydroxyethyl cellulose.


These two are important as construction chemicals and can be used as thickeners, water retention agents, and air-entraining agents.
Methylhydroxyethyl cellulose is excellent compatibility with other components and high biostability.
Methylhydroxyethyl cellulose dissolves fast and without mass, which helps to simplify the mixing process.



USES and APPLICATIONS of METHYLHYDROXYETHYL CELLULOSE:
A modified Methylhydroxyethyl cellulose developed for cement-based applications, such as cement-based tile adhesives.
Methylhydroxyethyl cellulose is compatible with all conventional mineral binders used.
Methyl Hydroxyethyl Cellulose (MHEC) alone or in combination is the most widely used cellulose in mortar formulations.


Methylhydroxyethyl cellulose provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, Methylhydroxyethyl cellulose is highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.


Methylhydroxyethyl cellulose provides good open time, slip resistance, adhesion and shear strength, according to different storage conditions.
The selected particle size distribution offers quick, lump free dissolution.
Methylhydroxyethyl cellulose has various properties such as thickening, emulsifying, binding, forming, protective colloid and water retention.


In decorative applications, Methylhydroxyethyl cellulose's found most often as a component of toothpaste and cough syrups.
Methylhydroxyethyl cellulose is tasteless and odorless, and in medicine, it is ingested by patients to relieve constipation, diarrhea, and hemorrhoids.
Methylhydroxyethyl cellulose also enhances workability and water retention.


The most significant Methylhydroxyethyl cellulose uses include its use in the production of adhesives, cosmetics, paper and textiles, pharmaceuticals, paint, and a host of other industrial applications.
Uses of Methylhydroxyethyl cellulose: Cement-based tile adhesives.


Methylhydroxyethyl cellulose has good viscosity stability and anti-mildew degeneration during long-term storage.
Methylhydroxyethyl cellulose has a good performance in coatings and building materials.
Methylhydroxyethyl cellulose used as a high efficient water retention agent, stabilizer, adhesive and film-forming agent in kinds of building materials.


Methylhydroxyethyl cellulose, also known as Hydroxyethyl cellulose or hydroxyethyl ether, is a thickening and gelling agent that comes from cellulose which is used in cleaning solutions and in cosmetics.
Methylhydroxyethyl cellulose is also used in cement-based tile adhesives and grouts.


Methylhydroxyethyl cellulose is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
Methylhydroxyethyl cellulose is extruded concrete plank.
Methylhydroxyethyl cellulose enhances the processing performance of extruded products, with high bonding strength and lubrication.


Methylhydroxyethyl cellulose improves the adhesiveness of wet strength and sheet extrusion.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.


Mainly, these are used in cement and gypsum-based dry mix mortar to increase bond strength, workability, and water retention.
Methylhydroxyethyl cellulose is a product used for manufacturing of wall putty and tiles adhesives
Methylhydroxyethyl cellulose is non surface treated grade, used for various mortars especially under dry mix system.


Methylhydroxyethyl cellulose offers premium level of water retention and strong adhesion.
Methylhydroxyethyl cellulose (HEMC or MHEC) are excellent thickener and water retaining agents in construction industries for tile glue, grouts, skim coat, and cement render.


Methylhydroxyethyl cellulose is used water based paint and paint remover.
Methylhydroxyethyl cellulose enhances the viscosity of the water-based paint remover and organic solvent, so that the paint remover will not flow out of the surface of the workpiece.


Methylhydroxyethyl cellulose has a good anti-mildew ability because it contains hydroxyethyl groups.
Multiple grades and tailored formulations are available to suit various industrial needs.
Methylhydroxyethyl cellulose is also used to control consistency, flow and leveling, high shear viscosity, and storage stability of interior and exterior flat emulsion paints.


Methylhydroxyethyl cellulose is excellent in water solubility, water retention, surface activity, thickening, film formation, adhesion, suspension, and high-temperature resistance.
Methyl Hydroxyethyl Cellulose (MHEC) is a kind of Cellulose Ethers, which is mainly used as adhesive protective gelatin, thicker agent, stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets


Methylhydroxyethyl cellulose is widely used to maintain water content in waterborne coatings and varnishes, control the rheology and consistency of waterborne coatings, stabilize pigments and fillers, as adhesives and viscosity control agents in enamel, as thickeners in printing inks, and as thickeners in textile coatings.


Methylhydroxyethyl cellulose is widely used in various industries, including tile adhesives, grouts, skim coat/wall putty, cement renders, gypsum-based products, cement-based mortars.
Methylhydroxyethyl cellulose is mainly used as water retaining agent and thickener in cement-based materials.


Methylhydroxyethyl cellulose can also shows delayed solubility.
Due to its high degree of methoxylation, Methylhydroxyethyl cellulose is the only cellulose derivative with the best water retention, which is the only reason why MHEC is sold for use in cement-based wall putties and mortars.


Methylhydroxyethyl cellulose can thicken, suspend, agglutinate, float, and provide protective colloid, for this reason, it is mainly used as an adhesive, thickener, and emulsifying additive.
Methylhydroxyethyl cellulose is a high-efficiency water retention agent because its aqueous solution has good hydrophilicity.


Methylhydroxyethyl cellulose offers premium level of water retention and strong adhesion.
According to experts, Methylhydroxyethyl cellulose also improves the performance of cement and gypsum based materials.
Methylhydroxyethyl cellulose ensures fast hydration for reliable performance.


Methylhydroxyethyl cellulose's water retaining function can prevent the base material from absorbing too much and too quickly and prevent the evaporation of water, so as to ensure that there is enough water when the cement is hydrated.
Methylhydroxyethyl cellulose is a water soluble substance.


For industrial usages, Methylhydroxyethyl cellulose's different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Except for the construction industry, Methylhydroxyethyl cellulose is also used in the food industry, daily chemicals, and other fields.
Methylhydroxyethyl cellulose can increase the workability of mortar.


Methylhydroxyethyl cellulose ensures fast hydration for reliable performance.
To avoid the lump formation, Methylhydroxyethyl cellulose is suggested to use it in dry from before the water is added, as it dissolve rapidly.
In the food industry, Methylhydroxyethyl cellulose is used as adhesion, emulsification, film formation, thickening, suspending, dispersing, water retention agents, etc.


In daily chemicals, Methylhydroxyethyl cellulose is used as an additive for toothpaste, cosmetics, and detergent.
According to experts, Methylhydroxyethyl cellulose also improves the performance of cement and gypsum based materials.
Methylhydroxyethyl cellulose is a water soluble substance.


Methylhydroxyethyl cellulose is used as a food additive.
Methylhydroxyethyl cellulose is also playing useful roles in kinds of building materials.
Methylhydroxyethyl cellulose has stronger water retention than methylcellulose, stronger viscosity stability, mildew resistance, and dispersion than hydroxyethyl cellulose.


Make Methylhydroxyethyl cellulose easier for constructors to operate.
As a non-ionic cellulose ether, Methylhydroxyethyl cellulose powder has a good stabilization and thickening effect in paint, which can make the paint produce good wear resistance.


Methylhydroxyethyl cellulose can be used as the adhesive for plastering mortar, gypsum materials, putty powder and other building materials to improve the coating performance and prolong the service time.
Methylhydroxyethyl cellulose is also playing useful roles in kinds of building materials.


Methylhydroxyethyl cellulose is non surface treated grade, used for various mortars especially under dry mix system.
Methylhydroxyethyl cellulose can be used in different building materials: Tile adhesive, Cement mortar, Joint filler, Self-levelling compound, External wall insulation, Gypsum based plaster, Ceramic extrusion.


Methylhydroxyethyl cellulose cellulose powder is widely used in the building industry.
Methylhydroxyethyl cellulose could dissolve in water and form a clear solution with specific viscosity.
Methylhydroxyethyl cellulose have a good stability even though in alkaline environment and provide a good stability in heat environment.


For industrial usages, Methylhydroxyethyl cellulose's different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Methylhydroxyethyl cellulose can also be used to paste ceramic tiles, marble, plastic decoration, paste reinforcing agent, and reduce the amount of corresponding materials.


Methylhydroxyethyl cellulose offers very good temperature stability and compatibility with many materials including surfactants and polymers such as CMC, starch ether, guar gum and alginates.
Methylhydroxyethyl cellulose is widely used in tile adhesives, dry mix mortar, joint filler, wall putty/skim coat, self-leveling floor, gypsum plaster, EIFS, and detergent.


Methylhydroxyethyl cellulose is widely used in wall putty and tile adhesives.
Methylhydroxyethyl cellulose is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
The lubricity of Methylhydroxyethyl cellulose can greatly improve the mortar workability (such as improve the bond strength of mortar, reduce water absorption, and enhance anti-sag of mortar), which is helpful for improving work efficiency.


To avoid the lump formation, Methylhydroxyethyl cellulose is suggested to use it in dry form before the water is added, as it dissolve rapidly.
Methylhydroxyethyl cellulose is widely used in drymix mortar industry, oil drilling, detergent and paint ＆ costings etc.
For example, Methylhydroxyethyl cellulose can be used in tile adhesive, joint filler, self-leveling mortar, plaster, skim coat, paint and coatings, etc.


Methylhydroxyethyl cellulose can be used as a protective colloids, suspending agent and binder and stabilizer.
Methylhydroxyethyl cellulose is widely used in drymix mortar industry, oil drilling, detergent and paint ＆ costings etc.
Methylhydroxyethyl cellulose has several properties used in the pharmaceutical and construction industries.


-Dispersing Agent:
When mixed with other chemicals, Methylhydroxyethyl cellulose works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.
This makes Methylhydroxyethyl cellulose useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.


-Uses of Methylhydroxyethyl cellulose:
*Construction：
Cement mortar, Concrete mix, Gypsum-based hand and machine plasters
*Painting：
Latex paint, polymer emulsified, Thickening, water retention, retarding Interior paints Exterior paints
*Silicone resin-based paints, Jamb mortars Papermaking:
Sizing agent, Thickener, water-retaining
*Cosmetics：
Toothpaste, shampoo, Detergent， Thickener, stabilizer
*Petroleum Oil：
Widely used in well drilling, filling liquids, Water retention, Thickening, Liquid loss control industrial applications


-Soil Stabilizers:
Methylhydroxyethyl cellulose is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Methylhydroxyethyl cellulose can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Methylhydroxyethyl cellulose allows nutrients to remain available to plants over more extended periods than untreated fertilizers.


-Cement plaster:
Methylhydroxyethyl cellulose improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability.
Methylhydroxyethyl cellulose enhance liquidity and pumpability, thus improving working efficiency.
High water retention, prolong the working time of mortar, improve work efficiency, and facilitate the formation of high mechanical strength during solidification period.
Control the infiltration of air, thus eliminating the microcracks of the coating and forming the ideal smooth surface.


-Food Production:
Methylhydroxyethyl cellulose is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Methylhydroxyethyl cellulose serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Methylhydroxyethyl cellulose is also added to baked goods, salad dressings, and salad gums.
Methylhydroxyethyl cellulose helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.


-Moisturizer and surfactant:
Methylhydroxyethyl cellulose is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
Methylhydroxyethyl cellulose is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Methylhydroxyethyl cellulose can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.


-Applications of Methylhydroxyethyl cellulose:
*Skim coat / wall putty
*Tile adhesives
*Joint fillers
*Cement mortar/Masonry mortar
*Cement based plasters
*External insulation and finish systems (EIFS)
*Grout
*Self Leveling
*Detergent


-Herbicide:
Some farmers use Methylcellulose as an herbicide. When mixed with water and sprinkled on certain plants, Methylhydroxyethyl cellulose can help prevent growth or kill the plant entirely.
Methylhydroxyethyl cellulose helps the herbicide stay in place without being washed away by water or carried away by the wind.


-Tile adhesive:
Methylhydroxyethyl cellulose makes the dry mixing ingredients easy to mix, and will not produce a mass, thus saving working time.
As the application is faster and more effective, Methylhydroxyethyl cellulose can improve the construction and reduce the cost.
Methylhydroxyethyl cellulose improve the efficiency of tiling by lengthening the cooling time. Provides excellent adhesion effect.
Special development model with high anti-skid resistance can be provided.
Self-leveling the ground material.



-Concrete Mixes:
Concrete mixes using Methylhydroxyethyl cellulose are commonly used for their smoothness and strength.
Methylhydroxyethyl cellulose is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.


-Applications
*Wall putty/skim coat
*Plaster/render
*Tile grout
*Plaster/render


-Cosmetics:
Methylhydroxyethyl cellulose is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Like other uses for methyl hydroxyethyl cellulose, Methylhydroxyethyl cellulose's used to increase the viscosity of these products and make them easier to apply.


-Cosmetic Uses:
*stabilising agents
*viscosity controlling agents


-Binding agent:
Methylhydroxyethyl cellulose is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Methylhydroxyethyl cellulose is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.


-Applications of Methylhydroxyethyl cellulose:
*Adhesives
*Binders
*Coatings
*Construction


-Masonry mortar:
Strengthen the adhesion of the surface of the masonry, and enhance the water retention, so as to improve the strength of mortar.
Improve the lubrication and plasticity so as to improve the construction performance, and use the mortar made of “guaranteed” cellulose ether to make it easier to apply and save time, and improve the cost-effectiveness.

The model with special high water retention can be used for high absorbent bricks.
Methylhydroxyethyl cellulose is used to fill the material.
Excellent water retention, Methylhydroxyethyl cellulose can prolong cooling time and improve working efficiency.

Methylhydroxyethyl cellulosehas high lubricity, make use easier, smooth.
Methylhydroxyethyl cellulose improves the anti-contractility and crack resistance and improve the surface quality.
Methylhydroxyethyl cellulose provides smooth and uniform texture, and make the joint surface more cohesive.


-Drymix Mortar:
Methylhydroxyethyl cellulose for dry mix mortar increases pumping ability and makes the mortar easy to apply.
Maintain enough moisture in the mortar and reach the best performance.


-Paper Production:
Due to the low toxicity of Methylhydroxyethyl cellulose and its ability to improve the properties of paper while decreasing production costs, MHE has gained wide acceptance in the paper manufacturing industry.
Methylhydroxyethyl cellulose can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage; it can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.


-Cement:
Methylhydroxyethyl cellulose helps increase the efficiency of cement by prolonging water retention and hydration reactions.
This helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Methylhydroxyethyl cellulose can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.


-Tile Adhesive:
Methylhydroxyethyl cellulose for tile adhesive significantly improves compatibility and stickiness, reduces moisture evaporation, and makes the tiles firmly attach to the wall or floor without sagging or sliding.


-Medicine:
You may have taken Methylhydroxyethyl cellulose without even knowing it.
That's because Methylhydroxyethyl cellulose has been used in manufacturing pharmaceutical products for decades.
Methylhydroxyethyl cellulose works as an excipient (a sense included with an active drug that binds together all ingredients).
Furthermore, Methylhydroxyethyl cellulose can be used to coat pills and help slow down their release into the body.


-Gypsum plaster:
Methylhydroxyethyl cellulose improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability to enhance the mobility and pumpability.
Thus, the work efficiency is improved.
High water retention, longer working time of mortar, and high mechanical strength during solidification.
A high quality surface coating is formed by controlling the consistency of the mortar.


-Joint Filler:
Methylhydroxyethyl cellulose for joint filler is stable and durable even at high temperatures, particularly in hot weather, and strong cohesiveness boosts construction performance.
Make the construction more straightforward.


-Oil drilling:
Methylhydroxyethyl cellulose uses is also used in oil drilling operations to thicken liquids used in the exploration process.
This helps ensure that Methylhydroxyethyl cellulose can be pumped through pipes without dripping or spilling, making them less effective at their intended function.


-Applications:
Methylhydroxyethyl cellulose is used tile Grouts, Tiles Adhesive, White Cement based wall putty, Water based Latex Paint, Printing Ink, Oil Drilling, Dry & Wet Mortar series, Construction & Building Material, Retaining Water & improving constructability, Thickening Agent, Decorative Plaster, Gypsum, Detergent etc.


-Wall Putty/Skim Coat:
Methylhydroxyethyl cellulose for wall putty/skim coat is a versatile building material for interior and exterior walls.
Methylhydroxyethyl cellulose restrains water loss and maintains a certain level of moisture.


-Paints and coatings:
Methylhydroxyethyl cellulose, also known as MHEC and Methylcellulose, is a thickening agent used in paints and coatings.
Methylhydroxyethyl cellulose can help prevent paint from sagging and dripping when it dries.

The combination can also help provide the color with extra adhesion, making Methylhydroxyethyl cellulose helpful in constructing buildings.
Methylhydroxyethyl cellulose is commonly used as a thickening agent in decorative paints.

Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Methylhydroxyethyl cellulose provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.
Methylhydroxyethyl cellulose also helps make paint that has been applied easier to clean.


-EIFS:
EIFS is the short form for Exterior Insulation and Finish Systems. Methylhydroxyethyl cellulose in EIFS provides adhering strength with good consistency and is sag resistant.
Methylhydroxyethyl cellulose improves workability and efficiency.


-Thickening agent:
Methylhydroxyethyl cellulose uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, Methylhydroxyethyl cellulose coats the hair strands to protect them from water damage.
Because Methylhydroxyethyl cellulose is water-soluble, it does not cause build-up on hair strands after repeated use of the product containing it.


-Detergent:
Detergent grade Methylhydroxyethyl cellulose quickly dissolved in cold water, acted as an efective colloidal protective agent, thickener, emulsifier and dispersant, good viscosity stability during long-term storage.


-Self Leveling:
Methylhydroxyethyl cellulose for self leveling compound is a good suspension agent, applicable for indoor floor coverings, water retention power good for liquidity and achieving a smooth surface.


-Applications
◉ Exterior wall adhesive mortar
◉ Interior and exterior wall putty
◉ Good tensile adhesive strength
◉ Tile adhesive glue
◉ Cement-based mortar
◉ Gypsum-based mortar


-Application of Methylhydroxyethyl cellulose:
Methylhydroxyethyl cellulose was specially designed for cement based applications like cement based tiles adhesives, plasters/ render, skim coats/wall putty & External thermal insulation system.



PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
*Water retention and adhesive power
*High-temperature resistance
*Dispersant and suspension ability
*A perfect thickener and film formation agent



FEATURES OF METHYLHYDROXYETHYL CELLULOSE:
◉ Excellent water retention capacity
◉ Good salt-resistant capacity
◉ pH stability
◉ Good film-forming ability
◉ Thickening ability
◉ Extensive enzyme resistance



PHYSICAL PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
Methylhydroxyethyl cellulose appears to be white powder and is odorless and tasteless.
Methylhydroxyethyl cellulose is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Methylhydroxyethyl cellulose will swell into colloidal solution and its solybility is not influenced by PH value.
Similar to methyl cellulose while being added to Hdroxyethyl groups.
Methylhydroxyethyl cellulose is more resistant to saline, easily soluble in water and has higher gel temperature.



BENEFITS OF METHYLHYDROXYETHYL CELLULOSE:
*Good open time
*Good adhesion and shear strength
*Good water retention at elevated temperatures
*Good adjustment time



PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
● Good thickening / thickening efficiency
● Available in a wide range of molecular weight and viscosity
● Excellent properties as a water-retaining agent
● Excellent resistance to dissolved inorganic salts
● Excellent solution clarity
● Low toxicity and environmental protection
● High water retention
● Long open time
● Good workability
● Good heat resistance



WHAT IS THE DIFFERENCE BETWEEN HPMC AND METHYLHYDROXYETHYL CELLULOSE?
HPMC and Methylhydroxyethyl cellulose are modified cellulose forms that are mainly used as gelling agents for thickening properties in different items.
The key difference between HPMC and Methylhydroxyethyl cellulose is that the gel temperature of HPMC is around 60 – 75 ℃ depending on the group content and different production techniques, whereas the gel temperature of MHEC is usually higher than 80 ℃.



KEY PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE:
- Improves workability
- Reduce water absorption
- Increase adhesion strength



WHY METHYLHYDROXYETHYL CELLULOSE IS BEING PREFERRED OVER HPMC FOR CELLULOSE ETHER?
Cellulose Ether is derived from Cellulose and is a water-soluble compound used in several industries.
It finds its usage mainly in the construction, food, pharmaceutical, and cosmetics industries.
Specifically, Cellulose Ether is primarily used in the construction sector as it acts as a binder, thickener, and water retention agent in construction.

There are different grades of Cellulose Ether, which have their applicability and properties.
The two primary grades of Cellulose Ether HPMC (Hydroxypropyl Methyl Cellulose) and Methylhydroxyethyl cellulose have varied similarities, yet one is more preferred than the other in recent days.

Nowadays, Methylhydroxyethyl cellulose grade of Cellulose Ether is more preferred than the HPMC grade in the construction industry.
Though, both are being utilized widely for increasing bond strength and water retention capacity of a dry mixture of cement and gypsum, few properties differentiate them.
The first property differentiating Methylhydroxyethyl cellulose from HPMC is gel temperature; the gel temperature of MHEC is higher than that of Methylhydroxyethyl cellulose.

The gel temperature of HPMC is around 60°c - 70°c, which varies as per its content and production technique; however, the gel temperature of Methylhydroxyethyl cellulose is generally more than 80°C, which makes it a better alternative.
Methylhydroxyethyl cellulose has better thermal stability owing to its high gel temperature, causing better water retention capacity during summers in South Asian Countries.

Furthermore, Methylhydroxyethyl cellulose has a more significant number of Hydrophilic groups in its structure, eventually leading to more hydrophilicity than the HPMC grade.
Having more Hydrophilic groups makes Methylhydroxyethyl cellulose better in water retention, and hence it is preferred more.
In addition, the prices of Methylhydroxyethyl cellulose grades have been lesser than that of HPMC, making them more economical to use.
In India, the prices of Cellulose Ether, with respective to all grades, have been marginally increasing from the first week of April.

According to ChemAnalyst, “Methylhydroxyethyl cellulosegrade would be chosen over HPMC grade in countries including India as summers have already approached.
Construction industries would go for having cellulose ether with higher gel temperature and better hydrophilicity.
Furthermore, the Indian domestic market of Cellulose Ether is most likely to showcase stagnant to a marginal rise in the prices.”



PHYSICAL and CHEMICAL PROPERTIES of METHYLHYDROXYETHYL CELLULOSE:
Appearance: white or off-white
Moisture: ≤5%
Ash: ≤5%
Etherification(MS/DS): 0.8-1.2/1.8-2.0
pH value: 6-8
Gel temperature: 70-85°C
Viscosity: 1,000-75,000 mPa.s (Brookfield RV, 2%)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Molecular Weight: 858.9
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 24
Rotatable Bond Count: 17
Exact Mass: 858.39440297
Monoisotopic Mass: 858.39440297
Topological Polar Surface Area: 332 Ų
Heavy Atom Count: 58
Formal Charge: 0
Complexity: 884
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 20
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Appearance: White powder
Loss on drying: ≤5%
PH: 4.0-8.0



FIRST AID MEASURES of METHYLHYDROXYETHYL CELLULOSE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated lothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLHYDROXYETHYL CELLULOSE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLHYDROXYETHYL CELLULOSE:
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLHYDROXYETHYL CELLULOSE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLHYDROXYETHYL CELLULOSE:
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of METHYLHYDROXYETHYL CELLULOSE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane
2-hydroxyethyl methyl cellulose
Cellulose, 2-hydroxyethyl methyl ether
Methyl hydroxyethyl cellulose
9032-42-2
methyl 2-hydroxyethyl cellulose
ethane-1,2-diol

DESCRIPTION:

Methylhydroxyethyl cellulose (MHEC) is a gelling and thickening agent derived from cellulose.
Methylhydroxyethyl cellulose (MHEC) is short-term for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose (MHEC)'s produced from a natural renewable polymer, wood pulp, or refined cotton.



CAS NUMBER: 9032-42-2

MOLECULAR FORMULA: C34H66O24

MOLECULAR WEIGHT: 858.9 g/mol



DESCRIPTION:

Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether that evolved from the addition of ethylene oxide to methylcellulose.
Methylhydroxyethyl cellulose (MHEC) can be white to off-white powder, but it's odorless regardless of color, safe for all animal species, and environmentally friendly.
Methylhydroxyethyl cellulose (MHEC) is widely used in tile adhesives, dry mix mortar, joint filler, wall putty/skim coat, self-leveling floor, gypsum plaster, EIFS, and detergent.
Methylhydroxyethyl cellulose (MHEC) is non-ionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
Methylhydroxyethyl cellulose (MHEC) is a kind of odorless and tasteless.

Methylhydroxyethyl cellulose (MHEC) is an off-white powder or granule.
Methylhydroxyethyl cellulose (MHEC) dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.
Methylhydroxyethyl cellulose (MHEC) ether can be used in any area where thickening, gelling, emulsifying, stabilizing processes and providing water retention and good workability properties are required.
Methylhydroxyethyl cellulose (MHEC) is a synthetic substance that is used as a thickening and emulsifying agent in many products, including foods, pharmaceuticals, and cosmetics.

Methylhydroxyethyl cellulose (MHEC) has been shown to inhibit the activity of certain enzymes, such as amylase, lipase, and protease.
In addition to these properties, Methylhydroxyethyl cellulose (MHEC) is also known for its high degree of thermal stability and light resistance.
Methylhydroxyethyl cellulose (MHEC) can be used in a wide range of applications due to its versatility and low cost.
Methylhydroxyethyl cellulose (MHEC) provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention.
Methylhydroxyethyl cellulose (MHEC) are highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.

Methylhydroxyethyl cellulose (MHEC) is an organic compound methyl hydroxyethyl cellulose uses in various cosmetic and medical applications, the primary one being as a thickening agent.
Methylhydroxyethyl cellulose (MHEC)'s found most often as a component of toothpaste and cough syrups.
Methylhydroxyethyl cellulose (MHEC) uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, the material coats the hair strands to protect them from water damage.

Methylhydroxyethyl cellulose (MHEC) is water-soluble, methyl hydroxyethyl cellulose does not cause build-up on hair strands after repeated use of the product containing it.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic water-soluble polymer.
Methylhydroxyethyl cellulose (MHEC) has been used in manufacturing pharmaceutical products for decades.
Methylhydroxyethyl cellulose (MHEC) works as an excipient (a sense included with an active drug that binds together all ingredients).

Methylhydroxyethyl cellulose (MHEC) can be used to coat pills and help slow down their release into the body.
Methylhydroxyethyl cellulose (MHEC) is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Methylhydroxyethyl cellulose (MHEC) is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.
Due to the low toxicity of Methylhydroxyethyl cellulose (MHEC) and its ability to improve the properties of paper while decreasing production costs, Methylhydroxyethyl cellulose (MHEC) has gained wide acceptance in the paper manufacturing industry.

Methylhydroxyethyl cellulose (MHEC) can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage.
Methylhydroxyethyl cellulose (MHEC) can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.
When mixed with other chemicals, Methylhydroxyethyl cellulose (MHEC) works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.

This makes it useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.
Methylhydroxyethyl cellulose (MHEC) is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Methylhydroxyethyl cellulose (MHEC) can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Methylhydroxyethyl cellulose (MHEC) allows nutrients to remain available to plants over more extended periods than untreated fertilizers.

Methylhydroxyethyl cellulose (MHEC) is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
A surfactant is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Methylhydroxyethyl cellulose (MHEC) can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.
Concrete mixes using Methylhydroxyethyl cellulose (MHEC) are commonly used for their smoothness and strength.
Methylhydroxyethyl cellulose (MHEC) is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.

Methylhydroxyethyl cellulose (MHEC) is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Methylhydroxyethyl cellulose (MHEC) serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Methylhydroxyethyl cellulose (MHEC) is also added to baked goods, salad dressings, and salad gums.
Methylhydroxyethyl cellulose (MHEC) helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.
Methylhydroxyethyl cellulose (MHEC) helps increase the efficiency of cement by prolonging water retention and hydration reactions.

Methylhydroxyethyl cellulose (MHEC) helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Methylhydroxyethyl cellulose (MHEC) can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.
A modified Methylhydroxyethyl cellulose (MHEC) developed for gypsum-based applications, such as gypsum manualr and spray plasters.
Compatible with all conventional mineral binders used in plaster formulation, Methylhydroxyethyl cellulose (MHEC) provides good mixing properties through adopted particle morphology,high water retentions and adjusted plaster workability, according to specific application segment.
The selected particle size distribution offers quick, lump free dissolution. and prevents the formation of lumps during mixing.

Methylhydroxyethyl cellulose (MHEC) is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.
Methylhydroxyethyl cellulose (MHEC) is a thickening and gelling agent that comes from cellulose which is used in cleaning solutions and in cosmetics.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic, water soluble cellulose ether intended as a water retaining and consistency improving additive to cement based mortars.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether polymer based on cellulose, a natural polymer derived from refine cotton linter.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether made from natural high polymer cellulose.

Methylhydroxyethyl cellulose (MHEC) is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.
Methylhydroxyethyl cellulose (MHEC) can be used in different building materials.
Methylhydroxyethyl cellulose (MHEC) uses is also used in oil drilling operations to thicken liquids used in the exploration process.
Methylhydroxyethyl cellulose (MHEC) helps ensure that the fluid can be pumped through pipes without dripping or spilling, making them less effective at their intended function.

Methylhydroxyethyl cellulose (MHEC) is used as an excipient in a wide range of pharmaceutical products, including oral tablets and suspensions, and topical gel preparations.
Methylhydroxyethyl cellulose (MHEC) has similar properties to methylcellulose, but the hydroxyethyl groups make it more readily soluble in water and solutions are more tolerant of salts and have a higher coagulation temperature.
Methylhydroxyethyl cellulose (MHEC) is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Methylhydroxyethyl cellulose (MHEC) is a thickening agent used in paints and coatings.

Methylhydroxyethyl cellulose (MHEC) can help prevent paint from sagging and dripping when it dries.
The combination can also help provide the color with extra adhesion, making it helpful in constructing buildings.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent in decorative paints.
Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Methylhydroxyethyl cellulose (MHEC) provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.

Methylhydroxyethyl cellulose (MHEC) also helps make paint that has been applied easier to clean.
Methylhydroxyethyl cellulose (MHEC) is a cellulose ether, which is based on methyl cellulose.
Methylhydroxyethyl cellulose (MHEC) has several properties in pharma and construction industries.
Methylhydroxyethyl cellulose (MHEC) is better performance in terms of higher gel temperature and hydrophilicity rely on ethyl substituent groups.
Methylhydroxyethyl cellulose (MHEC) is excellent thickener and water retaining agents in construction industries for tile glue, grouts, skim coat, and cement render.



USES:

-Water retention aid
-thickening agent
-protective colloid
-suspending agent
-binder and stabilizer
-Gypsum spray plaster
-Gypsum manual plaster
-Lime gypsum plaster




USAGE AREAS:

Construction：

-Cement mortar
-Concrete mix
-Gypsum-based hand and Machine plasters


Painting：

-Latex paint
-polymer emulsified
-Thickening
-water retention
-retarding Interior paints Exterior paints Silicone resin-based paints
-Jam mortars


Papermaking：

-Sizing agent
-Thickener
-waterstop


Cosmetics：

-Toothpaste
-shampoo
-Detergent
-Thickener
-stabilizer



USAGE:

-Drymix Mortar
-Drymix Mortar
-Paint & Coatings
-Home Care
-Ceramic



APPLICATION:

HBR can be used as a protective colloid, stabilizer and suspending agent.
It offers very good pseudoplastic flow characteristics and broad compatibility with other materials such as emulsion polymers, natural and synthetic gums, emulsifiers, defoamers, pigments, surfactants and preservatives.


-Interior wall latex paint
-Exterior wall latex paint
-Real stone paint
-Texture paint



BENEFITS:

-Good mixing properties
-Improved workability
-Good water retention at elevated temperatures
-High standing strength



FEATURES:

-Water retention and adhesive power
-High-temperature resistance
-Dispersant and suspension ability
-A perfect thickener and film formation agent
-Excellent stability against enzymes
-Good solubility, easy to use
-Excellent viscosity stability
-Excellent water retention, extended open time
-Suitable for various lotion types



SPECIFICATION:

-Appearance: white or off-white
-Moisture: ≤5%
-Ash: ≤5%
-Etherification(MS/DS): 0.8-1.2/1.8-2.0
-pH value: 6-8
-Gel temperature: 70-85°C
-Viscosity: 1,000-75,000 mPa.s (Brookfield RV, 2%)



PROPERTIES:

-Purity: 98%
-Type: Powder
-Usage: Coating Auxiliary Agents
-Model Number: 250 HHBR
-Appearance: POWDER
-Moisture content, %,: max 5
-Color: white
-Ash content %,: maximum: 5.5
-Hydration time at pH 8.0: 4-25 minutes
-Viscosity: 3400-5000 cps
-Density g/ml: 1.38



PROPERTIES:

-Appearance: White and off-white powder
-Particle size: 98% — 100%
-Moisture content (%): ≤5.0
-PH value: 5.0-8.0



SPECIFICATION:

-surface tension: 45-55 dyn/cm, 20 °C, 0.1 wt. %
-viscosity: 15,000-20,500 cP, 2 wt. % in H2O(20 °C, Brookfield, spindle #6) (20 rpm)(lit.)
-transition temp: flocculation range 60-90 °C (0.5 wt. %)
-Molecular Weight: 858.9 g/mol
-Hydrogen Bond Donor Count: 10
-Hydrogen Bond Acceptor Count: 24
-Rotatable Bond Count: 17
-Exact Mass: 858.39440297 g/mol
-Monoisotopic Mass: 858.39440297 g/mol
-Topological Polar Surface Area: 332Ų
-Heavy Atom Count: 58
-Complexity: 884
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 20
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 3
-Compound Is Canonicalized: Yes



STORAGE:

Hydroxyethylmethyl cellulose is hygroscopic and should therefore be stored under dry conditions away from heat.



SYNONYM:

methyl 2-hydroxyethyl cellulose
9032-42-2
FT-0612598

Methylhydroxyethyl cellulose (MHEC) is a gelling and thickening agent derived from cellulose.
Methylhydroxyethyl cellulose (MHEC), also known as Methylcellulose and colloquium, is an organic compound methyl hydroxyethyl cellulose uses in various cosmetic and medical applications, the primary one being as a thickening agent.


CAS Number: 9032-42-2
Chemical formula: variable


Methylhydroxyethyl cellulose (MHEC) is nonionic cellulose ether produced from natural polymer material through the processing of etherification reaction.
Methylhydroxyethyl cellulose (MHEC) is a kind of odorless, tasteless, non-toxic white powder or granule.
Methylhydroxyethyl cellulose (MHEC) dissolves in hot and cold water, forms a transparent viscous solution and is insoluble in common organic solvents.


Methylhydroxyethyl cellulose (MHEC) is a white, odorless powder.
Methylhydroxyethyl cellulose (MHEC) is ether of cellulose and ethylene oxide mainly used as adhesive protective gelatin, thicker agent and stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets.


Methylhydroxyethyl cellulose (MHEC) is a water soluble.
The term HPMC stands for hydroxypropyl methyl cellulose, while the term Methylhydroxyethyl cellulose (MHEC) stands for methyl hydroxyethyl cellulose.
These two are important as construction chemicals and can be used as thickeners, water retention agents, and air-entraining agents.


Methylhydroxyethyl cellulose (MHEC) stands for methyl hydroxyethyl cellulose.
Methylhydroxyethyl cellulose (MHEC) is a gelling and thickening agent that is derived from cellulose.
The chemical formula of this compound is variable because the number of unit structures per Methylhydroxyethyl cellulose (MHEC) molecule can vary.


Therefore, the molar mass also varies accordingly.
Methylhydroxyethyl cellulose (MHEC) is considered to be non-toxic.
Methylhydroxyethyl cellulose (MHEC) can be described as a modified cellulose polymer consisting of methyl, ethyl, and hydroxyethyl side chains.


Methylhydroxyethyl cellulose (MHEC) is a nonionic cellulose derivative that dissolves readily in water, either cold or hot.
Compared to other cellulose ether chemistries, the methylcellulose derivatives have a slightly more Newtonian flow characteristic which provides increased high-shear (ICI) viscosity.


Methylhydroxyethyl cellulose (MHEC) is water soluble, nonionic cellulose ethers, which are offered as free flowing powder or in granular form.
Methylhydroxyethyl cellulose (MHEC) may contain further additives which for example control the dissolution behavior or the thickening power.
Methyl Hydroxyethyl Cellulose (MHEC), in the form of a powder, is a thickening agent.


Methylhydroxyethyl cellulose (MHEC) can be used in water-based latex paints and printing inks.
Methylhydroxyethyl cellulose (MHEC)'s pH value exists between 5.0 and 8.0.
Methylhydroxyethyl cellulose (MHEC) is water soluble nonionic cellulose ethers, which are offered as free flowing powder or in granular form cellulose.


Methylhydroxyethyl cellulose (MHEC) is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.
Methylhydroxyethyl cellulose (MHEC) appears to be white powder and is odorless and tasteless.


Methylhydroxyethyl cellulose (MHEC) is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Methylhydroxyethyl cellulose (MHEC) will swell into colloidal solution and its solubility is not influenced by PH value.
Similar to methyl cellulose while being added to Hydroxyethyl groups.


Methylhydroxyethyl cellulose (MHEC) is more resistant to saline, easily soluble in water and has higher gel temperature. Methylhydroxyethyl cellulose (MHEC) is also known as HEMC, Methyl Hydroxyethyl Cellulose, which can be used as highly efficient water retention agent, stabilizer, adhesives and film-forming agent in construct.
Methylhydroxyethyl cellulose (MHEC) is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.


Methylhydroxyethyl cellulose (MHEC) is medium-high viscosity construction grade Methyl Hydroxyethyl Cellulose widely used in building materials.
Methylhydroxyethyl cellulose (MHEC) could be soluble in water to form a transparent solution
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether that widely used in construction materials.


Methylhydroxyethyl cellulose (MHEC) could be dissolved in hot or cold water to form a transparent solution with a particular viscosity.
The properties of Methylhydroxyethyl cellulose (MHEC) and methylcellulose are similar, but the presence of hydroxyethyl makes Methylhydroxyethyl cellulose (MHEC) cellulose more soluble in water, the solution is more compatible with salt and has a higher aggregation temperature.


Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether made from natural high polymer cellulose.
Methylhydroxyethyl cellulose (MHEC) is an odourless, tasteless and non-toxic white powder, which can be dissolved in cold water to form a transparent viscous solution.
Methylhydroxyethyl cellulose (MHEC) is made from highly pure cotton-cellulose by reaction of etherification under alkaline conditions without any organs of animals, fat and other bioactive constituents.


Methylhydroxyethyl cellulose (MHEC) is also called as Hydroxyethyl Methyl Cellulose HEMC.
Methylhydroxyethyl cellulose (MHEC) is a non-ionic cellulose ether made from natural high polymer cellulose.
Methylhydroxyethyl cellulose (MHEC) offers many of the same advantages as other methyl cellulose derivatives, such as effective thickening and moisture retention.


Methylhydroxyethyl cellulose (MHEC) is a white, yellow-white or off-white powder or granules, hygroscopic after drying.
Methylhydroxyethyl cellulose (MHEC) is a methylcellulose based cellulose.
Methylhydroxyethyl cellulose (MHEC) is a kind of methyl cellulose derivative which is made from natural high polymer cellulose.


Methylhydroxyethyl cellulose (MHEC) could dissolve in water and form a clear solution with specific viscosity.
Methylhydroxyethyl cellulose (MHEC) has a good stability even though in alkaline environment and provide a good stability in heat environment.
Methylhydroxyethyl cellulose (MHEC) provides viscosity, which can be used as an anti – precipitation agent.


Methylhydroxyethyl cellulose (MHEC) enhances the liquidity and pumpability, thus improving the efficiency of the flooring.
Control water retention, thus greatly reducing cracking and shrinkage.
Methylhydroxyethyl cellulose (MHEC) is excellent compatibility with other components and high biostability.


Methylhydroxyethyl cellulose (MHEC) dissolves fast and without mass, which helps to simplify the mixing process.
The cold water disperses the model product, can make the mix more quick and convenient, and does not produce the mass.
Generate favorable flow characteristics, including low spatter and good leveling, to ensure fine surface finish and prevent the flow of paint.



USES and APPLICATIONS of METHYLHYDROXYETHYL CELLULOSE (MHEC):
The most significant Methylhydroxyethyl cellulose (MHEC) uses include its use in the production of adhesives, cosmetics, paper and textiles, pharmaceuticals, paint, and a host of other industrial applications.
Cellulose ether can be used in any area where thickening, gelling, emulsifying, stabilizing processes and providing water retention and good workability properties are required.


Methylhydroxyethyl cellulose (MHEC) provides many of the same benefits as other methylcellulose derivatives, such as the ability to efficiently thicken and provide water retention, Methylhydroxyethyl cellulose (MHEC) is highly effective additives used to improve the quality and processing characteristics of building materials such as plasters and renders, mortars, tile adhesives, joint compounds and emulsion paints.


Methylhydroxyethyl cellulose (MHEC) can thicken, suspend, agglutinate, float, and provide protective colloid, for this reason, it is mainly used as an adhesive, thickener, and emulsifying additive.
Methylhydroxyethyl cellulose (MHEC) is a high-efficiency water retention agent because its aqueous solution has good hydrophilicity.


Methylhydroxyethyl cellulose (MHEC) has a good anti-mildew ability because it contains hydroxyethyl groups.
Methylhydroxyethyl cellulose (MHEC) has good viscosity stability and anti-mildew degeneration during long-term storage.
Methylhydroxyethyl cellulose (MHEC) has a good performance in coatings and building materials.


Methylhydroxyethyl cellulose (MHEC) has stronger water retention than methylcellulose, stronger viscosity stability, mildew resistance, and dispersion than hydroxyethyl cellulose.
Methylhydroxyethyl cellulose (MHEC) used as a high efficient water retention agent, stabilizer, adhesive and film-forming agent in kinds of building materials.


In decorative applications, Methylhydroxyethyl cellulose (MHEC)'s found most often as a component of toothpaste and cough syrups.
Methylhydroxyethyl cellulose (MHEC) is tasteless and odorless, and in medicine, it is ingested by patients to relieve constipation, diarrhea, and hemorrhoids.
Mainly, these are used in cement and gypsum-based dry mix mortar to increase bond strength, workability, and water retention.


Therefore, Methylhydroxyethyl cellulose (MHEC) is used as a food additive.
Methyl Hydroxyethyl Cellulose (MHEC) is a kind of Cellulose Ethers, which is mainly used as adhesive protective gelatin, thicker agent, stabilizing agent as well as additives to make emulsion, frozen gelatin, lotion, eye clear agent, suppository and tablets


Methylhydroxyethyl cellulose (MHEC) is a water soluble substance.
For industrial usages, Methylhydroxyethyl cellulose (MHEC)'s different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Methylhydroxyethyl cellulose (MHEC) is also playing useful roles in kinds of building materials.


Methylhydroxyethyl cellulose (MHEC) is non surface treated grade, used for various mortars especially under dry mix system.
Methylhydroxyethyl cellulose (MHEC) offers premium level of water retention and strong adhesion.
According to experts, Methylhydroxyethyl cellulose (MHEC) also improves the performance of cement and gypsum based materials.


Methylhydroxyethyl cellulose (MHEC) ensures fast hydration for reliable performance.
To avoid the lump formation, Methylhydroxyethyl cellulose (MHEC) is suggested to use it in dry from before the water is added, as it dissolve rapidly.
Methylhydroxyethyl cellulose (MHEC) is a water soluble substance.


For industrial usages, Methylhydroxyethyl cellulose (MHEC)'s different forms are: water retention agent, stabilizer, adhesives and film forming agent.
Methylhydroxyethyl cellulose (MHEC) is also playing useful roles in kinds of building materials.
Methylhydroxyethyl cellulose (MHEC) is non surface treated grade, used for various mortars especially under dry mix system.


Methylhydroxyethyl cellulose (MHEC) offers premium level of water retention and strong adhesion.
According to experts, Methylhydroxyethyl cellulose (MHEC) also improves the performance of cement and gypsum based materials.
Methylhydroxyethyl cellulose (MHEC) ensures fast hydration for reliable performance.


To avoid the lump formation, Methylhydroxyethyl cellulose (MHEC) is suggested to use it in dry form before the water is added, as it dissolve rapidly.
Methylhydroxyethyl cellulose (MHEC) is widely used in wall putty and tile adhesives.
Methylhydroxyethyl cellulose (MHEC) is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.


Methylhydroxyethyl cellulose (MHEC) could dissolve in water and form a clear solution with specific viscosity.
Methylhydroxyethyl cellulose (MHEC) have a good stability even though in alkaline environment and provide a good stability in heat environment.
Methylhydroxyethyl cellulose (MHEC) is widely used in drymix mortar industry, oil drilling, detergent and paint ＆ costings etc.


Methylhydroxyethyl cellulose (MHEC) can be used in different building materials: Tile adhesive, Cement mortar, Joint filler, Self-levelling compound, External wall insulation, Gypsum based plaster, Ceramic extrusion.
Methylhydroxyethyl cellulose (MHEC) cellulose powder is widely used in the building industry.


For example, Methylhydroxyethyl cellulose (MHEC) can be used in tile adhesive, joint filler, self-leveling mortar, plaster, skim coat, paint and coatings, etc.
As a non-ionic cellulose ether, Methylhydroxyethyl cellulose (MHEC) powder has a good stabilization and thickening effect in paint, which can make the paint produce good wear resistance.


The lubricity of Methylhydroxyethyl cellulose (MHEC) can greatly improve the mortar workability (such as improve the bond strength of mortar, reduce water absorption, and enhance anti-sag of mortar), which is helpful for improving work efficiency.
Except for the construction industry, Methylhydroxyethyl cellulose (MHEC) is also used in the food industry, daily chemicals, and other fields.


In the food industry, Methylhydroxyethyl cellulose (MHEC) is used as adhesion, emulsification, film formation, thickening, suspending, dispersing, water retention agents, etc.
In daily chemicals, Methylhydroxyethyl cellulose (MHEC) is used as an additive for toothpaste, cosmetics, and detergent.


Methylhydroxyethyl cellulose (MHEC) is widely used to maintain water content in waterborne coatings and varnishes, control the rheology and consistency of waterborne coatings, stabilize pigments and fillers, as adhesives and viscosity control agents in enamel, as thickeners in printing inks, and as thickeners in textile coatings.
Methylhydroxyethyl cellulose (MHEC) can be used as a protective colloids, suspending agent and binder and stabilizer.


Methylhydroxyethyl cellulose (MHEC) offers very good temperature stability and compatibility with many materials including surfactants and polymers such as CMC, starch ether, guar gum and alginates.
Methylhydroxyethyl cellulose (MHEC) is also used to control consistency, flow and leveling, high shear viscosity, and storage stability of interior and exterior flat emulsion paints.


Methylhydroxyethyl cellulose (MHEC) can also shows delayed solubility.
Due to its high degree of methoxylation, Methylhydroxyethyl cellulose (MHEC) is the only cellulose derivative with the best water retention, which is the only reason why MHEC is sold for use in cement-based wall putties and mortars.


Methylhydroxyethyl cellulose (MHEC) is also used in cement-based tile adhesives and grouts.
Methylhydroxyethyl cellulose (MHEC) is widely used in many different industries as water retention agent, thickener, adhesive agent and dispersant etc.
Methylhydroxyethyl cellulose (MHEC) is widely used in drymix mortar industry, oil drilling, detergent and paint ＆ costings etc.


Methylhydroxyethyl cellulose (MHEC) has several properties used in the pharmaceutical and construction industries.
Methyl Hydroxyethyl Cellulose (MHEC) alone or in combination is the most widely used cellulose in mortar formulations.
Methylhydroxyethyl cellulose (MHEC) has various properties such as thickening, emulsifying, binding, forming, protective colloid and water retention.


Methylhydroxyethyl cellulose (MHEC) is used water based paint and paint remover.
Methylhydroxyethyl cellulose (MHEC) enhances the viscosity of the water-based paint remover and organic solvent, so that the paint remover will not flow out of the surface of the workpiece.


Methylhydroxyethyl cellulose (MHEC) is extruded concrete plank.
Methylhydroxyethyl cellulose (MHEC) enhances the processing performance of extruded products, with high bonding strength and lubrication.
Methylhydroxyethyl cellulose (MHEC) improves the adhesiveness of wet strength and sheet extrusion.


-Applications:
Methylhydroxyethyl cellulose (MHEC) is used tile Grouts, Tiles Adhesive, White Cement based wall putty, Water based Latex Paint, Printing Ink, Oil Drilling, Dry & Wet Mortar series, Construction & Building Material, Retaining Water & improving constructability, Thickening Agent, Decorative Plaster, Gypsum, Detergent etc.


-Thickening agent:
Methylhydroxyethyl cellulose (MHEC) uses to thickener in cosmetic products such as shampoos and conditioners because it can form a film on hair strands.
This film makes hair appear smooth and shiny.
In addition, Methylhydroxyethyl cellulose (MHEC) coats the hair strands to protect them from water damage.
Because Methylhydroxyethyl cellulose (MHEC) is water-soluble, it does not cause build-up on hair strands after repeated use of the product containing it.


-Medicine:
You may have taken Methylhydroxyethyl cellulose (MHEC) without even knowing it.
That's because Methylhydroxyethyl cellulose (MHEC) has been used in manufacturing pharmaceutical products for decades.
Methylhydroxyethyl cellulose (MHEC) works as an excipient (a sense included with an active drug that binds together all ingredients).
Furthermore, Methylhydroxyethyl cellulose (MHEC) can be used to coat pills and help slow down their release into the body.


-Binding agent:
Methylhydroxyethyl cellulose (MHEC) is an excellent binding agent or adhesive because it forms a gel when mixed with water.
Methylhydroxyethyl cellulose (MHEC) is often used in the manufacture of pills and capsules because it binds together different pill components to create uniform tablets that are easy to swallow.


-Paper Production:
Due to the low toxicity of Methylhydroxyethyl cellulose (MHEC) and its ability to improve the properties of paper while decreasing production costs, MHE has gained wide acceptance in the paper manufacturing industry.
Methylhydroxyethyl cellulose (MHEC) can be used as a dry strength agent in paper production to increase tensile strength without increasing gram mage; it can also be used as a pigment binder in paper coatings and water retention agents in paper due to its good properties as a dispersing agent.


-Dispersing Agent:
When mixed with other chemicals, Methylhydroxyethyl cellulose (MHEC) works as a dispersing agent because it absorbs water to form a gel while keeping the ingredients in suspension.
This makes Methylhydroxyethyl cellulose (MHEC) useful in various applications, including household products like laundry detergent, foods like whipped cream, cosmetics like toothpaste, and pharmaceuticals like cough syrups or eye drops.


-Soil Stabilizers:
Methylhydroxyethyl cellulose (MHEC) is used as a soil stabilizer to increase the yield of crops on marginal land and in areas where irrigation is not practical.
Methylhydroxyethyl cellulose (MHEC) can be mixed with water and applied to soil to improve moisture retention during dry periods or when rainfall is sparse.
When incorporated into fertilizer formulas, Methylhydroxyethyl cellulose (MHEC) allows nutrients to remain available to plants over more extended periods than untreated fertilizers.


-Moisturizer and surfactant:
Methylhydroxyethyl cellulose (MHEC) is also used as a moisturizer and surfactant in cosmetics, baby lotions, shampoos, and bath oils.
Methylhydroxyethyl cellulose (MHEC) is a wetting agent that lowers the surface tension of liquids and allows them to spread over a surface.
Methylhydroxyethyl cellulose (MHEC) can be used as an emulsifier that keeps water-based and oil-based ingredients mixed in cosmetics.


-Herbicide:
Some farmers use Methylcellulose as an herbicide. When mixed with water and sprinkled on certain plants, Methylhydroxyethyl cellulose (MHEC) can help prevent growth or kill the plant entirely.
Methylhydroxyethyl cellulose (MHEC) helps the herbicide stay in place without being washed away by water or carried away by the wind.


-Concrete Mixes:
Concrete mixes using Methylhydroxyethyl cellulose (MHEC) are commonly used for their smoothness and strength.
Methylhydroxyethyl cellulose (MHEC) is used to coat the interior surface of concrete pipes, giving them a uniform thickness that reduces wear over time.
This method also produces lines resistant to cracking when exposed to water, heat, or other harsh conditions.


-Food Production:
Methylhydroxyethyl cellulose (MHEC) is commonly used as an ingredient in the production of commercially-made ice cream due to its ability to stabilize the product.
Methylhydroxyethyl cellulose (MHEC) serves as an alternative to gelatin and vegetable gum such as guar gum and locust bean gum.
Methylhydroxyethyl cellulose (MHEC) is also added to baked goods, salad dressings, and salad gums.
Methylhydroxyethyl cellulose (MHEC) helps prevent sugar crystallization and increases the shelf life of food products by controlling moisture content.


-Uses of Methylhydroxyethyl cellulose (MHEC):
*Construction： Cement mortar, Concrete mix ， Gypsum-based hand and machine plasters
*Painting： Latex paint, polymer emulsified， Thickening, water retention, retarding Interior paints Exterior paints
*Silicone resin-based paints, Jamb mortars Papermaking: Sizing agent, Thickener, water-retaining
*Cosmetics： Toothpaste, shampoo, Detergent， Thickener, stabilizer
*Petroleum Oil： Widely used in well drilling, filling liquids， Water retention, Thickening， Liquid loss control industrial applications


-Applications of Methylhydroxyethyl cellulose (MHEC):
*Adhesives
*Binders
*Coatings
*Construction


-Cement:
Methylhydroxyethyl cellulose (MHEC) helps increase the efficiency of cement by prolonging water retention and hydration reactions.
This helps reduce the amount of glue required during construction projects, ultimately lowering costs.
Methylhydroxyethyl cellulose (MHEC) can also be added to concrete mixes to improve their structural properties, such as flexural strength, compressive strength, and tensile strength.


-Oil drilling:
Methylhydroxyethyl cellulose (MHEC) uses is also used in oil drilling operations to thicken liquids used in the exploration process.
This helps ensure that Methylhydroxyethyl cellulose (MHEC) can be pumped through pipes without dripping or spilling, making them less effective at their intended function.


-Cosmetics:
Methylhydroxyethyl cellulose (MHEC) is found in many cosmetic products, including hair sprays, shampoos, conditioners, toothpaste, and soaps.
Like other uses for methyl hydroxyethyl cellulose, Methylhydroxyethyl cellulose (MHEC)'s used to increase the viscosity of these products and make them easier to apply.


-Paints and coatings:
Methylhydroxyethyl cellulose (MHEC), also known as MHEC and Methylcellulose, is a thickening agent used in paints and coatings.
Methylhydroxyethyl cellulose (MHEC) can help prevent paint from sagging and dripping when it dries.
The combination can also help provide the color with extra adhesion, making Methylhydroxyethyl cellulose (MHEC) helpful in constructing buildings.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent in decorative paints.
Decorative paints are not as strong as structural paints, so they need thickening agents to help them adhere to walls and other surfaces without breaking apart or peeling away.
Methylhydroxyethyl cellulose (MHEC) provides water resistance to decorative paints, making it more difficult for walls to become damaged by exposure to water.
Methylhydroxyethyl cellulose (MHEC) also helps make paint that has been applied easier to clean.


-Cement plaster:
Methylhydroxyethyl cellulose (MHEC) improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability.
Methylhydroxyethyl cellulose (MHEC) enhance liquidity and pumpability, thus improving working efficiency.
High water retention, prolong the working time of mortar, improve work efficiency, and facilitate the formation of high mechanical strength during solidification period.
Control the infiltration of air, thus eliminating the microcracks of the coating and forming the ideal smooth surface.


-Gypsum plaster:
Methylhydroxyethyl cellulose (MHEC) improve homogeneity, make the mortar more easily coated, and improve the anti-sagging ability to enhance the mobility and pumpability.
Thus, the work efficiency is improved.
High water retention, longer working time of mortar, and high mechanical strength during solidification.
A high quality surface coating is formed by controlling the consistency of the mortar.


-Masonry mortar:
Strengthen the adhesion of the surface of the masonry, and enhance the water retention, so as to improve the strength of mortar.
Improve the lubrication and plasticity so as to improve the construction performance, and use the mortar made of “guaranteed” cellulose ether to make it easier to apply and save time, and improve the cost-effectiveness.

The model with special high water retention can be used for high absorbent bricks.
Methylhydroxyethyl cellulose (MHEC) is used to fill the material.
Excellent water retention, Methylhydroxyethyl cellulose (MHEC) can prolong cooling time and improve working efficiency.

Methylhydroxyethyl cellulose (MHEC)has high lubricity, make use easier, smooth.
Methylhydroxyethyl cellulose (MHEC) improves the anti-contractility and crack resistance and improve the surface quality.
Methylhydroxyethyl cellulose (MHEC) provides smooth and uniform texture, and make the joint surface more cohesive.


-Tile adhesive:
Methylhydroxyethyl cellulose (MHEC) makes the dry mixing ingredients easy to mix, and will not produce a mass, thus saving working time.
As the application is faster and more effective, Methylhydroxyethyl cellulose (MHEC) can improve the construction and reduce the cost.
Methylhydroxyethyl cellulose (MHEC) improve the efficiency of tiling by lengthening the cooling time. Provides excellent adhesion effect.
Special development model with high anti-skid resistance can be provided.
Self-leveling the ground material.



PHYSICAL PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE (MHEC):
Methylhydroxyethyl cellulose (MHEC) appears to be white powder and is odorless and tasteless.
Methylhydroxyethyl cellulose (MHEC) is featured by hygroscopicity and hardly soluble in hot water, acetone, ethanol and toluene.
In cold water Methylhydroxyethyl cellulose (MHEC) will swell into colloidal solution and its solybility is not influenced by PH value.
Similar to methyl cellulose while being added to Hdroxyethyl groups.
Methylhydroxyethyl cellulose (MHEC) is more resistant to saline, easily soluble in water and has higher gel temperature.



PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE (MHEC):
● Good thickening / thickening efficiency
● Available in a wide range of molecular weight and viscosity
● Excellent properties as a water-retaining agent
● Excellent resistance to dissolved inorganic salts
● Excellent solution clarity
● Low toxicity and environmental protection



KEY PROPERTIES OF METHYLHYDROXYETHYL CELLULOSE (MHEC):
- Improves workability
- Reduce water absorption
- Increase adhesion strength



WHY METHYLHYDROXYETHYL CELLULOSE (MHEC) IS BEING PREFERRED OVER HPMC FOR CELLULOSE ETHER?
Cellulose Ether is derived from Cellulose and is a water-soluble compound used in several industries.
It finds its usage mainly in the construction, food, pharmaceutical, and cosmetics industries.
Specifically, Cellulose Ether is primarily used in the construction sector as it acts as a binder, thickener, and water retention agent in construction.

There are different grades of Cellulose Ether, which have their applicability and properties.
The two primary grades of Cellulose Ether HPMC (Hydroxypropyl Methyl Cellulose) and Methylhydroxyethyl cellulose (MHEC) have varied similarities, yet one is more preferred than the other in recent days.

Nowadays, Methylhydroxyethyl cellulose (MHEC) grade of Cellulose Ether is more preferred than the HPMC grade in the construction industry.
Though, both are being utilized widely for increasing bond strength and water retention capacity of a dry mixture of cement and gypsum, few properties differentiate them.
The first property differentiating Methylhydroxyethyl cellulose (MHEC) from HPMC is gel temperature; the gel temperature of MHEC is higher than that of Methylhydroxyethyl cellulose (MHEC).

The gel temperature of HPMC is around 60°c - 70°c, which varies as per its content and production technique; however, the gel temperature of Methylhydroxyethyl cellulose (MHEC) is generally more than 80°C, which makes it a better alternative.
Methylhydroxyethyl cellulose (MHEC) has better thermal stability owing to its high gel temperature, causing better water retention capacity during summers in South Asian Countries.

Furthermore, Methylhydroxyethyl cellulose (MHEC) has a more significant number of Hydrophilic groups in its structure, eventually leading to more hydrophilicity than the HPMC grade.
Having more Hydrophilic groups makes Methylhydroxyethyl cellulose (MHEC) better in water retention, and hence it is preferred more.
In addition, the prices of Methylhydroxyethyl cellulose (MHEC) grades have been lesser than that of HPMC, making them more economical to use.
In India, the prices of Cellulose Ether, with respective to all grades, have been marginally increasing from the first week of April.

According to ChemAnalyst, “Methylhydroxyethyl cellulose (MHEC)grade would be chosen over HPMC grade in countries including India as summers have already approached.
Construction industries would go for having cellulose ether with higher gel temperature and better hydrophilicity.
Furthermore, the Indian domestic market of Cellulose Ether is most likely to showcase stagnant to a marginal rise in the prices.”



WHAT IS THE DIFFERENCE BETWEEN HPMC AND METHYLHYDROXYETHYL CELLULOSE (MHEC)?
HPMC and Methylhydroxyethyl cellulose (MHEC) are modified cellulose forms that are mainly used as gelling agents for thickening properties in different items.
The key difference between HPMC and Methylhydroxyethyl cellulose (MHEC) is that the gel temperature of HPMC is around 60 – 75 ℃ depending on the group content and different production techniques, whereas the gel temperature of MHEC is usually higher than 80 ℃.



PHYSICAL and CHEMICAL PROPERTIES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
Molecular Weight: 858.9
Hydrogen Bond Donor Count: 10
Hydrogen Bond Acceptor Count: 24
Rotatable Bond Count: 17
Exact Mass: 858.39440297
Monoisotopic Mass: 858.39440297
Topological Polar Surface Area: 332 Ų
Heavy Atom Count: 58
Formal Charge: 0
Complexity: 884
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 20
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 3
Compound Is Canonicalized: Yes
Appearance: White powder
Loss on drying: ≤5%
PH: 4.0-8.0



FIRST AID MEASURES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated lothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Extinguishing media:
*Suitable extinguishing media:
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Precautions for safe handling:
*Advice on protection against fire and explosion:
Take precautionary measures against static discharge.
*Hygiene measures:
Change contaminated clothing.
Preventive skin protection recommended.
Wash hands after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of METHYLHYDROXYETHYL CELLULOSE (MHEC):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-hydroxyethyl methyl cellulose
Cellulose, 2-hydroxyethyl methyl ether
Methyl hydroxyethyl cellulose
9032-42-2
methyl 2-hydroxyethyl cellulose
ethane-1,2-diol
(2S,3R,4R,5S,6R)-2-(hydroxymethyl)-6-[(2S,3R,4S,5S,6S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
(2S,3S,4R,5S,6S)-2,3,4-trimethoxy-6-(methoxymethyl)-5-[(2R,3S,4R,5S,6S)-3,4,5-trimethoxy-6-(methoxymethyl)oxan-2-yl]oxyoxane

Methylhydroxyethyl cellulose (MHEC) is a chemical compound derived from cellulose, a natural polymer found in plants.
Methylhydroxyethyl cellulose (MHEC) is a cellulose ether, which means it is a modified form of cellulose obtained by chemical reactions.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent, stabilizer, and water retention agent in various industries, including construction, pharmaceuticals, cosmetics, and food.

CAS Number: 9032-42-2
EC Number: 618-391-6

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APPLICATIONS


Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent in construction materials.
Methylhydroxyethyl cellulose (MHEC) is added to cement-based products such as mortars, grouts, and tile adhesives to improve their consistency and workability.
Methylhydroxyethyl cellulose (MHEC) enhances the adhesion of construction materials to substrates, ensuring better bonding.

Methylhydroxyethyl cellulose (MHEC) acts as a water retention agent, preventing premature drying and improving the curing process of cementitious formulations.
In pharmaceuticals, MHEC is utilized as a binder and viscosity modifier in tablet formulations.
Methylhydroxyethyl cellulose (MHEC) helps control the release of active ingredients and ensures uniform drug distribution.

Methylhydroxyethyl cellulose (MHEC) is used in ophthalmic solutions to increase viscosity and improve ocular contact time.
In cosmetics and personal care products, MHEC serves as a thickener and stabilizer in creams, lotions, and shampoos.
Methylhydroxyethyl cellulose (MHEC) enhances the texture and appearance of cosmetic formulations and improves their spreadability.

Methylhydroxyethyl cellulose (MHEC) is employed in food products as a thickener, stabilizer, and emulsifier.
Methylhydroxyethyl cellulose (MHEC) enhances the texture and consistency of sauces, dressings, and desserts.
In paints and coatings, MHEC is added to improve viscosity, flow, and leveling.
Methylhydroxyethyl cellulose (MHEC) acts as a rheology modifier, preventing sagging and improving paint film formation.

Methylhydroxyethyl cellulose (MHEC) is used in adhesive formulations to improve tackiness and bonding strength.
Methylhydroxyethyl cellulose (MHEC) is added to wallpaper pastes, wood glues, and other adhesives for better adhesion.
In detergents and cleaning products, MHEC functions as a thickener and stabilizer.
Methylhydroxyethyl cellulose (MHEC) improves the viscosity and suspension properties of liquid and gel formulations.
MHEC is utilized in drilling fluids for oil and gas exploration as a viscosifier and fluid loss control agent.

In textile printing, MHEC is used as a thickener and binder in dye pastes and printing inks.
Methylhydroxyethyl cellulose (MHEC) ensures sharp printing definition and prevents bleeding of colors.
MHEC is employed in ceramic processing as a binder and rheology modifier in ceramic slurries.

Methylhydroxyethyl cellulose (MHEC) improves the green strength and shape retention of ceramic bodies during forming and drying.
In paper coatings, MHEC is added to improve surface smoothness and ink receptivity.
Methylhydroxyethyl cellulose (MHEC) enhances print quality and reduces ink absorption into the paper substrate.
Overall, Methylhydroxyethyl cellulose (MHEC) finds extensive use across various industries for its versatility and performance-enhancing properties.

Methylhydroxyethyl cellulose (MHEC) is utilized in the formulation of drilling muds for the oil and gas industry to provide viscosity control and fluid loss prevention.
In the production of ceramics, MHEC serves as a binder and plasticizer in clay bodies to improve molding and shaping properties.
Methylhydroxyethyl cellulose (MHEC) is added to detergents and cleaning products to thicken solutions and enhance their stability during storage.

Methylhydroxyethyl cellulose (MHEC) is used in air fresheners, fabric softeners, and dishwashing detergents to improve the overall performance of the products.
In the agricultural sector, MHEC is utilized as a thickening agent and adhesion promoter in crop protection formulations such as herbicides and pesticides.
Methylhydroxyethyl cellulose (MHEC) helps improve the sprayability and adherence of the active ingredients to plant surfaces.

Methylhydroxyethyl cellulose (MHEC) is incorporated into fire-retardant coatings and intumescent paints to enhance their fire resistance properties.
Methylhydroxyethyl cellulose (MHEC) forms a protective barrier when exposed to fire, delaying the spread of flames and reducing smoke emissions.
In the manufacturing of batteries, MHEC is used as a binder and thickener in electrolyte pastes for improved conductivity and stability.
Methylhydroxyethyl cellulose (MHEC) is added to ceramic glazes and enamels to adjust viscosity and improve their application properties.

Methylhydroxyethyl cellulose (MHEC) ensures even coating distribution and prevents drips and runs during firing.
In the production of textile printing pastes, MHEC acts as a thickener and rheology modifier to achieve precise printing results.
Methylhydroxyethyl cellulose (MHEC) helps control ink flow and prevents smudging or bleeding of printed designs.
Methylhydroxyethyl cellulose (MHEC) is used in the formulation of polymer dispersions and latex paints as a thickener and stabilizer.

Methylhydroxyethyl cellulose (MHEC) enhances the storage stability and application properties of water-based coatings.
In the manufacturing of asphalt emulsions, MHEC is added as a stabilizer and viscosity modifier to improve mix uniformity and coating durability.
Methylhydroxyethyl cellulose (MHEC) is employed in the production of ceramic membranes for water filtration applications as a binder and pore former.
Methylhydroxyethyl cellulose (MHEC) helps control pore size distribution and improves the filtration efficiency of the membranes.

In the formulation of personal care products such as toothpaste and mouthwash, MHEC acts as a thickener and binder to improve product texture and stability.
Methylhydroxyethyl cellulose (MHEC) is added to hair care products such as styling gels and mousses to provide hold and shape retention.
In the pharmaceutical industry, MHEC is used in controlled-release drug delivery systems to regulate drug release kinetics.
Methylhydroxyethyl cellulose (MHEC) ensures consistent and prolonged release of active ingredients for optimized therapeutic effects.

Methylhydroxyethyl cellulose (MHEC) is employed in the production of ceramic membranes for water treatment applications to remove contaminants and impurities from water sources.
Methylhydroxyethyl cellulose (MHEC) plays a crucial role in improving the efficiency and reliability of water purification processes.
Overall, Methylhydroxyethyl cellulose (MHEC) finds diverse applications across numerous industries due to its versatile properties and compatibility with various formulations and materials.

Methylhydroxyethyl cellulose (MHEC) is used in the formulation of polymer-modified bitumen for road construction applications to enhance durability and performance.
Methylhydroxyethyl cellulose (MHEC) improves the cohesion and adhesion properties of bituminous binders, reducing rutting and cracking.
In the production of fiberglass-reinforced plastics (FRP), MHEC serves as a binder and rheology modifier to improve resin flow and wetting of fibers.

Methylhydroxyethyl cellulose (MHEC) ensures uniform distribution of resin and reinforcement, enhancing the strength and structural integrity of FRP components.
In the agricultural industry, MHEC is added to seed coatings and fertilizers to improve adhesion and release properties.
Methylhydroxyethyl cellulose (MHEC) enhances the dispersibility and effectiveness of agricultural inputs, promoting uniform crop growth and yield.
Methylhydroxyethyl cellulose (MHEC) is used in the formulation of printing inks for packaging and labeling applications to improve print quality and adhesion to substrates.

Methylhydroxyethyl cellulose (MHEC) ensures sharp and vibrant printing results, even on challenging surfaces.
In the production of decorative coatings and textured finishes, MHEC serves as a thickener and rheology modifier to achieve desired aesthetics and surface effects.
Methylhydroxyethyl cellulose (MHEC) imparts body and consistency to coatings, facilitating application and enhancing surface texture.

Methylhydroxyethyl cellulose (MHEC) is employed in the manufacturing of textile sizing agents to improve fiber-to-fiber adhesion and reduce yarn breakage during weaving.
Methylhydroxyethyl cellulose (MHEC) enhances the strength and dimensional stability of woven fabrics, resulting in higher productivity and quality.
In the formulation of metalworking fluids, MHEC acts as a thickener and lubricity enhancer to improve machining performance and tool life.

Methylhydroxyethyl cellulose (MHEC) provides excellent boundary lubrication and chip evacuation, reducing friction and heat generation during metal cutting operations.
Methylhydroxyethyl cellulose (MHEC) is added to drilling fluids for geotechnical and environmental drilling applications to improve hole stability and borehole integrity.
Methylhydroxyethyl cellulose (MHEC) helps control fluid loss and filter cake formation, ensuring efficient drilling operations and environmental protection.

In the production of polymer dispersions for coatings and adhesives, MHEC serves as a thickener and stabilizer to improve formulation consistency and storage stability.
Methylhydroxyethyl cellulose (MHEC) enhances the film-forming properties and adhesion of water-based polymer coatings, ensuring long-lasting performance and durability.
Methylhydroxyethyl cellulose (MHEC) is utilized in the formulation of industrial cleaners and degreasers as a thickener and suspending agent to improve product stability and cleaning effectiveness.
Methylhydroxyethyl cellulose (MHEC) helps suspend and disperse soil and contaminants, facilitating their removal from surfaces.
In the manufacturing of industrial ceramics, MHEC is used as a binder and plasticizer to improve green strength and moldability of ceramic bodies.

Methylhydroxyethyl cellulose (MHEC) ensures uniform particle distribution and enhances the shaping and drying characteristics of ceramic compositions.
Methylhydroxyethyl cellulose (MHEC) is added to gypsum-based products such as plasters and joint compounds to improve workability, sag resistance, and surface finish.
Methylhydroxyethyl cellulose (MHEC) enhances the cohesiveness and smoothness of gypsum formulations, reducing cracking and improving aesthetic appeal.
Overall, Methylhydroxyethyl cellulose (MHEC) continues to find diverse applications across a wide range of industries, contributing to improved performance, efficiency, and quality of various products and processes.



DESCRIPTION


Methylhydroxyethyl cellulose (MHEC) is a chemical compound derived from cellulose, a natural polymer found in plants.
Methylhydroxyethyl cellulose (MHEC) is a cellulose ether, which means it is a modified form of cellulose obtained by chemical reactions.
Methylhydroxyethyl cellulose (MHEC) is commonly used as a thickening agent, stabilizer, and water retention agent in various industries, including construction, pharmaceuticals, cosmetics, and food.

Methylhydroxyethyl cellulose (MHEC) is synthesized through the reaction of cellulose with methyl chloride and ethylene oxide, resulting in the introduction of methyl and hydroxyethyl groups onto the cellulose backbone.
This modification enhances the water solubility and rheological properties of cellulose, making MHEC suitable for a wide range of applications.

In the construction industry, MHEC is commonly used as a thickener and water retention agent in cement-based products such as mortars, grouts, tile adhesives, and self-leveling compounds.
Methylhydroxyethyl cellulose (MHEC) improves the workability, consistency, and open time of these materials, allowing for easier application and better performance.

In pharmaceutical formulations, MHEC is used as a binder, film former, and viscosity modifier in tablet coatings, suspensions, and ophthalmic solutions.
Methylhydroxyethyl cellulose (MHEC) helps control the release of active ingredients, improve drug stability, and enhance the texture and appearance of dosage forms.

In cosmetics and personal care products, MHEC is employed as a thickener, emulsifier, and stabilizer in creams, lotions, shampoos, and other formulations.
Methylhydroxyethyl cellulose (MHEC) provides smooth texture, uniform consistency, and improved stability to these products.

Methylhydroxyethyl cellulose (MHEC) is a versatile cellulose ether widely used in various industries.
Methylhydroxyethyl cellulose (MHEC) is derived from natural cellulose through chemical modification processes.
Methylhydroxyethyl cellulose (MHEC) is a white to off-white, odorless powder with excellent water solubility.

Methylhydroxyethyl cellulose (MHEC) forms transparent and viscous solutions when dissolved in water.
Methylhydroxyethyl cellulose (MHEC) is valued for its thickening, stabilizing, and film-forming properties.

Methylhydroxyethyl cellulose (MHEC) is commonly employed as a thickener and rheology modifier in construction materials.
Methylhydroxyethyl cellulose (MHEC) improves the workability and consistency of cement-based products such as mortars and grouts.
Methylhydroxyethyl cellulose (MHEC) enhances the adhesion, cohesion, and open time of construction formulations.
Methylhydroxyethyl cellulose (MHEC) also acts as a water retention agent, reducing water loss during the curing process.
In pharmaceutical formulations, MHEC serves as a binder and film former in tablet coatings.

Methylhydroxyethyl cellulose (MHEC) controls the release of active ingredients and improves the appearance of dosage forms.
Methylhydroxyethyl cellulose (MHEC) is used in ophthalmic solutions to increase viscosity and prolong ocular contact time.
In cosmetics and personal care products, MHEC functions as a thickener and stabilizer.

Methylhydroxyethyl cellulose (MHEC) imparts smooth texture and uniform consistency to creams, lotions, and shampoos.
Methylhydroxyethyl cellulose (MHEC) enhances the spreadability and moisturizing properties of cosmetic formulations.
In food applications, MHEC acts as a thickener, stabilizer, and emulsifier.

Methylhydroxyethyl cellulose (MHEC) improves the texture, mouthfeel, and shelf life of food products such as sauces and dressings.
Methylhydroxyethyl cellulose (MHEC) is compatible with a wide range of other ingredients and additives.
Methylhydroxyethyl cellulose (MHEC) exhibits excellent compatibility with other polymers, surfactants, and preservatives.

Methylhydroxyethyl cellulose (MHEC) is non-ionic and therefore compatible with both cationic and anionic compounds.
Methylhydroxyethyl cellulose (MHEC) is stable over a wide pH range and in the presence of salts and oxidizing agents.
Methylhydroxyethyl cellulose (MHEC) is biodegradable and environmentally friendly, with low toxicity and eco-toxicity.

Methylhydroxyethyl cellulose (MHEC) undergoes controlled degradation in soil and water without causing harm to ecosystems.
Methylhydroxyethyl cellulose (MHEC) is manufactured under strict quality control standards to ensure consistency and purity.
Overall, Methylhydroxyethyl cellulose (MHEC) is a valuable additive that enhances the performance and functionality of various products across multiple industries.



PROPERTIES


Chemical Formula: Variable, depending on the degree of substitution and molecular weight.
Molecular Weight: Variable, depending on the degree of polymerization and substitution.
Content of Hydroxyethyl: 4%-12%
Content of Methoxy: 21%-31%
Ash Content: 2%-3%
Moisture: ≤5%
PH Value: 5-8.5
Gel Temperature: 65℃ -75℃
Water Retention: 90% - 98%
Viscosity(NDJ-1): 10,000-200,000 Mpas
Viscosity(Brookfield): 40000-85000 Mpas



FIRST AID


Inhalation:

If inhaled, remove the affected individual to fresh air immediately.
Assist the person in finding a comfortable position and encourage deep breathing.
If breathing difficulties persist or if the person is unconscious, seek medical attention immediately.
Provide artificial respiration if the person has stopped breathing but is still responsive.
Keep the affected person warm and calm while awaiting medical assistance.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected skin area with soap and water thoroughly for at least 15 minutes.
If irritation or redness develops, seek medical attention.
If skin irritation persists, apply a soothing cream or lotion to alleviate discomfort.
Rinse contaminated clothing and shoes thoroughly before reuse.


Eye Contact:

Flush the eyes with gently flowing lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses if present and easily removable after the initial flushing.
Seek immediate medical attention, even if there are no signs of discomfort or irritation.
Protect the unaffected eye from contamination while rinsing the affected eye.
Do not rub the eyes, as it may exacerbate irritation or injury.


Ingestion:

If swallowed accidentally, do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water to remove any residual chemical.
Do not give anything by mouth to an unconscious person.
Seek immediate medical attention or contact a poison control center for further guidance.
Provide medical personnel with information about the ingested amount and time of exposure.


General Measures:

Move the affected person to a well-ventilated area and provide fresh air.
Keep the person warm and calm, reassuring them while administering first aid.
Monitor vital signs such as breathing, pulse, and consciousness level.
Do not leave the affected person unattended, especially if they are experiencing symptoms.
If necessary, provide supportive measures such as oxygen therapy or cardiopulmonary resuscitation (CPR) according to trained personnel's instructions.


Medical Attention:

If symptoms persist or worsen after initial first aid measures, seek medical attention promptly.
Provide medical personnel with safety data sheets (SDS) or other relevant information about the chemical for proper treatment.
Follow any additional instructions or recommendations provided by medical professionals.
Keep the affected person under medical observation for any delayed or secondary effects.
Inform medical personnel of any pre-existing medical conditions or allergies that may affect treatment options.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles or face shield, and protective clothing, when handling Methylhydroxyethyl cellulose (MHEC).
Use respiratory protection, such as a dust mask or respirator, if there is a risk of inhalation of airborne particles.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations of dust or aerosols.
Avoid creating dust clouds by using handling techniques that minimize the generation of airborne particles.

Avoidance of Contact:
Avoid skin contact and inhalation of MHEC dust or aerosols.
Use appropriate handling procedures, such as scoops or dust masks, to minimize exposure during transfer or mixing operations.
Do not eat, drink, or smoke while handling MHEC, and wash hands thoroughly after handling to prevent accidental ingestion.

Spill and Leak Procedures:
Clean up spills immediately to prevent accidental exposure and environmental contamination.
Use absorbent materials, such as vermiculite or sand, to contain and absorb spilled material.
Avoid sweeping or blowing dust, as it may become airborne and spread contamination.
Dispose of contaminated materials according to local regulations and guidelines.


Storage:

Container Selection:
Store Methylhydroxyethyl cellulose (MHEC) in tightly sealed containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Ensure containers are labeled with the appropriate hazard warnings and handling instructions.

Temperature and Humidity:
Store MHEC in a cool, dry, and well-ventilated area away from direct sunlight and heat sources.
Avoid exposure to high temperatures or humidity, as it may affect the stability and performance of the product.

Compatibility:
Keep MHEC away from incompatible materials, including strong acids, bases, oxidizing agents, and reducing agents.
Store away from sources of ignition or heat to prevent the risk of fire or spontaneous combustion.

Segregation:
Segregate MHEC from food, beverages, and animal feed to prevent contamination.
Store away from sources of contamination, such as pesticides, fertilizers, or other chemicals.

Handling Practices:
Use appropriate handling equipment, such as scoops or funneling devices, to transfer MHEC between containers.
Avoid generating dust or aerosols during handling by minimizing agitation or mechanical stress.
Use caution when opening containers to prevent sudden release of dust or vapors.


Emergency Procedures:

Spills and Releases:
In case of a spill or release, evacuate the area and restrict access to prevent exposure to unprotected individuals.
Notify appropriate personnel, such as supervisors or emergency responders, and follow established spill response procedures.
Wear appropriate PPE, including respiratory protection, when cleaning up spills to avoid inhalation or skin contact.

First Aid:
In the event of exposure, follow the recommended first aid measures outlined in the safety data sheet (SDS) or product label.
Seek medical attention for individuals exposed to significant quantities or experiencing adverse effects.
Provide medical personnel with information about the chemical and exposure route for appropriate treatment.

Methylisothiazolinone is a chemical substance that is effective in eliminating and controlling the growth of potentially harmful bacteria.
Methylisothiazolinone, MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3.
Methylisothiazolinone is a white solid.


CAS Number: 2682-20-4
EC Number: 220-239-6
Chem/IUPAC Name: 2-Methyl-2H-isothiazol-3-one
Chemical formula: C4H5NOS


Methylisothiazolinone is a preservative.
Methylisothiazolinone is a common preservative used in the personal care industry.
Methylisothiazolinone is a clear, colourless liquid that is soluble in water.


Methylisothiazolinone is a preservative commonly used in water-based personal care products.
Methylisothiazolinone is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone has the chemical formula C4H5NOS.


Methylisothiazolinone is a synthetic chemical used for controlling microbial growth in water-containing solutions.
Any product that contains water is particularly susceptible to being spoiled by microbial growth, causing problems such as discoloration, unpleasant odors or breakdown.


Methylisothiazolinone is a chemical substance that is effective in eliminating and controlling the growth of potentially harmful bacteria.
Under certain conditions, microorganisms can even grow to potentially harmful levels.
Preservatives are designed to help prevent these problems.


Methylisothiazolinone is only one of a very limited number of broad spectrum preservatives - meaning it is effective against a variety of bacteria, yeasts and molds.
Methylisothiazolinone is an isothiazolinone based biocide and preservative used in personal care products.


Methylisothiazolinone and Methylchloroisothiazolinone were very common preservatives found in many liquid personal care and leave-in products throughout the 1980's and 90's - Shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps and detergents.


Methylisothiazolinone - also known as MI - is a synthetic preservative used in many consumer products, including cosmetics, pharmaceutical products and household cleansers, as well as industrial products and settings like jet fuels, printing inks and cooling tower water.



USES and APPLICATIONS of METHYLISOTHIAZOLINONE:
Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
Methylisothiazolinone is used for controlling microbial growth in water-containing solutions.


Methylisothiazolinone is typically used in a formulation with 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), in a 3:1 mixture (CMIT:MIT).
Methylisothiazolinone also has been used to control slime in the manufacture of paper products that contact food.
In addition, Methylisothiazolinone serves as an antimicrobial agent in latex adhesives and in paper coatings that also contact food.


Methylisothiazolinone is used to control slime-forming bacteria, fungi,
and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems and is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other speciality industrial products as a preservative.


Methylisothiazolinone is also used to control the growth of mold, mildew, and sapstain on wood products.
Formulations include soluble concentrated liquids and soluble concentrated solids.
Products containing Methylisothiazolinone are added to systems and industrial products using manual pouring and metered pumping methods, dip tanks and sprayers.


Methylisothiazolinone is a widely-used preservative; has been associated with allergic reactions.
Lab studies on the brain cells of mammals also suggest that Methylisothiazolinone may be neurotoxic.
Methylisothiazolinone is a widely used antiseptic, which can effectively kill algae, bacteria and fungi.


The active monomer, Methylisothiazolinone, can be widely used in industrial cooling water, oil field return tank water, paper industry, pipeline, coating, paint, rubber, cosmetics, photographic film and washing products and other industries.
Methylisothiazolinone can effectively kill a variety of bacteria at low concentrations, especially for the preservation of cosmetics and personal care products.


Methylisothiazolinone enhances the safety and shelf-life of products by preventing the growth of bacteria and yeasts.
Without preservatives like Methylisothiazolinone, products could start to smell unpleasant, change colour or grow moulds which can produce toxins which are harmful to health.


Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations.
Methylisothiazolinone is a preservative that is found in a wide array of liquid cosmetics, personal care products and cleaning products on the market today.
Methylisothiazolinone's function is to inhibit the growth of bacteria.


Methylisothiazolinone, along with other isothiazolinones, is a biocide widely used as a preservative in personal care products.
Methylisothiazolinone is also used in many industrial processes, such as paint and paper manufacturing, metalworking, mining, and sanitizing.
Methylisothiazolinone was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI).


Since 2005, Methylisothiazolinone has been widely used in cosmetics and household products, such as moist wipes, shampoos, cleaners and liquid laundry products.
Methylisothiazolinone is a preservative that’s active against bacteria, yeast, and fungi.


Methylisothiazolinone’s used in the manufacture of water-based cosmetics and personal care products.
Methylisothiazolinone’s also used in industrial processes, including the manufacture of paper coatings, detergents, paints, glue, cutting oils
Methylisothiazolinone, better known by the acronym MIT, is used as a synthetic preservative in cosmetics.


Methylisothiazolinone is mostly used with CMIT (Methylchloroisothiazolinone).
Methylisothiazolinone can be used by all hair types.
Methylisothiazolinone is more important to be conscious of any allergies or skin you might have before using products containing the ingredient.


Methylisothiazolinone or MIT is a preservative used in many consumer goods including cosmetic products, to preserve product quality and ensure consumer safety by preventing the growth of microbes.
Methylisothiazolinone is used to protect products from contamination by potentially pathogenic microbes (fungi and bacteria).


Methylisothiazolinone's use allows to ensure the product is safe for consumers.
Preservatives that are generally recommended for use only in rinse-off products such as cleansers or shampoos.
Methylisothiazolinone is known to be sensitizing when used in leave-on products.


Methylisothiazolinone is used paints, glues and cooling lubricants, household and industrial cleaning agents, stationery, lubricants, wood care and water treatment agents.
Methylisothiazolinone is a widely used preservative and biocide.


Methylisothiazolinone is used Baby care - lotions, wipes, diaper cream, bubble bath, shampoo, soap.
Methylisothiazolinone is used Industrial products, All purpose cleaner, Automatic dishwasher, Bath and shower cleaner, and Bleach products.
Methylisothiazolinone is used Building materials - adhesives, paints, resins, emulsions, Carpet care, Disinfectant, Fabric softener sheets, and Fabric treatment.


Methylisothiazolinone is used Floor care, Furniture polish, Hand dishwashing, and Household cleaner wipes.
Methylisothiazolinone is used Kitchen cleaners, Laundry detergent, Lice treatment, Metal cleaner, and Metal working fluids.
Methylisothiazolinone is used Oil controller, Oil field operations, Paper mills, Stain remover, and Surface cleaner.


Methylisothiazolinone is used Make-ups, Moisturizers, Nail Polish / Nail Polish Remover, Powders / Sprays, Shampoos / Conditioners, Shaving products, Soaps / Cleansers, Sunscreens and Self-Tanners, and Spermacides.
You will often see methylisothiazolinone mixed with methylchloroisothiazolinone (MCI) to make a particularly effective isothiazolinone preservative.


Methylisothiazolinone is a common preservative used in house cleaning supplies and personal care products, including makeup, lotions, shampoos, conditioners, dish soaps, laundry detergents, and more.
Methylisothiazolinone is also sometimes used for industrial purposes in painting, manufacturing, metalworking, mining, and sanitizing.


Methylisothiazolinone is also used for controlling microbial growth in water-containing solution.
Methylisothiazolinone is used Toilet bowl cleaner, Water cooling and treatment systems, Wood treatment, Skin Care Products / Cosmetics, Antiperspirants / Deodorants, Hair sprays, gels, tonics and lotions, and Hair Colorants / “Permanents-Relaxers.


Methylisothiazolinone is used to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites.
Methylisothiazolinone is a common preservative used in industrial products, owing to its strong biocide effect.


You can find Methylisothiazolinone in makeup items like foundation, eye shadow and mascara, as well as personal care items like moisturisers, sunscreen, lotions, gels, mouth wash, shampoos, soaps, body wash and wet wipes, including baby wipes.
Methylisothiazolinone’s also used in some over-the-counter and prescription medicines, along with household cleaning products, laundry detergents, polishes, adhesives, pesticides and so on.


Methylisothiazolinone has multiple commercial and industrial applications.
In cosmetic products, Methylisothiazolinone is most commonly used as a preservative in products such as sunscreens, shampoos, sanitary wipes, makeup and lotions.


Methylisothiazolinone’s industrial use includes energy production, metal working, and paint manufacturing.
Methylisothiazolinone is a commonly used synthetic biocide and preservative and is found in personal care and industrial applications.
Methylisothiazolinone is a preservative that can also be found in shampoos, skin care products and makeup.


Methylisothiazolinone helps maintain product quality and performance over time.
Some people raise concerns about preservatives, because a small number of individuals have allergies to them just as some people have allergies to nuts or bees.
But preservatives play a very important role in food, cosmetics and household products.


Without preservatives, many products would not last more than a week or two before being contaminated by bacteria, mold or yeast.
Methylisothiazolinone and other isothiazolinone-derived biocides are used to prevent microbial growth in liquid formulations, as such MIT is found mostly in liquid cosmetics and personal care formulations.



YOU MIGHT FIND METHYLISOTHIAZOLINONE IN:
*Shampoos and conditioners
*Hair colouring liquids
*Moisturising lotions
*Sun lotions
*Baby lotions
*Hairsprays
*Liquid soaps
*Detergents



WHAT IS METHYLISOTHIAZOLINONE USED FOR?
*Personal care products
*Makeup
*Baby hygiene products
*Sunscreens
*Liquid soaps
*Liquid laundry detergent
*Hair dye and treatments
*Some household cleaners
*Various industrial products like paint, glue, cutting oils, and paper coatings



FUNCTIONS OF METHYLISOTHIAZOLINONE:
*Preservative:
Methylisothiazolinone inhibits the development of microorganisms in cosmetic products.



MAIN BENEFITS OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone prevents bacteria growth in hair products



HOW OFTEN CAN YOU USE METHYLISOTHIAZOLINONE:
Methylisothiazolinone can be used daily



WORKS WELL WITH, METHYLISOTHIAZOLINONE:
There are no known interactions with other ingredients.



WHY IS METHYLISOTHIAZOLINONE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
Methylisothiazolinone and Methylchloroisothiazolinone (MCI) are preservatives.
Preservatives are natural or man-made ingredients designed to help ensure the safety and quality of products by protecting them against the growth of microorganisms during storage and, most importantly, during use by consumers.

Any product that contains water is particularly susceptible to being spoiled by microbial growth, causing problems such as discoloration, unpleasant odors or breakdown.
Under certain conditions, microorganisms can even grow to potentially harmful levels.

Preservatives are designed to help prevent these problems.
Although Methylisothiazolinone may be used in cosmetics and personal care products alone, it is often used as a mixture with Methylchloroisothiazolinone.
In cosmetics and personal care products historically, Methylisothiazolinone, or the mixture, Methylisothiazolinone and Methylchloroisothiazolinone, was used
in various rinse-off and leave-on formulations including hair products, shampoos, skin care products, bath products, eye and facial makeup, wet wipes and suntan products.



WHAT DOES METHYLISOTHIAZOLINONE DO IN A FORMULATION?
*Preservative



BENEFITS OF METHYLISOTHIAZOLINONE FOR HAIR:
Methylisothiazolinone does not have any benefits specifically for your hair.
Methylisothiazolinone won't make it shiny, more manageable, thicker, or stronger.
Methylisothiazolinone is strictly used in cosmetics as a preservative and bacteria-inhibitor, which is obviously an important thing we all want in a product we're keeping in a warm, damp place like the bathroom.

Even though Methylisothiazolinone doesn't have direct benefits for hair, it does have a number of benefits in a product formulation.
Methylisothiazolinone protects products at a very low-use level.
Methylisothiazolinone's also water soluble, making it very easy to mix in.
Methylisothiazolinone's also stable over a broad pH range, making it suitable for many types of formulas like shampoos and conditioners.



METHYLISOTHIAZOLINONE, A CLINICIAN'S POINT OF VİEW:
Methylisothiazolinone is also used in air fresheners such as Glade Premium Room Spray, and may be a preservative component of a product.
Specifically Methylisothiazolinone can be found in cleansers such as liquid dish soap, liquid laundry soap, all purpose spray cleaners and window cleaning solutions.
Methylisothiazolinone can also be found in products labeled "natural".
Corporations trying to sell "green" (but not so green) cleaners often use Methylisothiazolinone as a preservative.



WHAT ARE METHYLISOTHIAZOLINONE and METHYLCHLOROISOTHIAZOLINONE?
Methylisothiazolinone (MIT) and Methylchloroisothiazolinone (CMIT) are widely used preservatives found in liquid cosmetic and personal care products.
Both chemicals inhibit bacterial growth in cosmetic products on their own, but they are most commonly used as a mixture in products.



HOW TO USE METHYLISOTHIAZOLINONE FOR HAIR:
Methylisothiazolinone is a preservative used in haircare products like shampoos and conditioners.
If you have a known sensitivity be sure to read ingredient statements on cosmetics and personal care products, because of the small percentages used preservatives are typically at the end of the list.
FYI, this doesn't mean that if you do happen to find Methylisothiazolinone in your haircare, that you need to toss your products.



METHYLISOTHIAZOLINONE, FOUND IN:
*Shampoo
*Conditioner
*Hair color
*Body wash
*Lotion
*Sunscreen
*Mascara
*Shaving cream
*Baby lotion
*Baby shampoo
*Hairspray
*Makeup remover
*Liquid soaps and detergents.



FUNCTIONS OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone (MIT) is a new fungicide introduced from Europe.
Isothiazolinone organic compounds can inhibit the growth and reproduction of various microorganisms (such as bacteria, fungi, yeast, etc.), and are widely used broad-spectrum fungicides.
Compared with other types of fungicides, isothiazolinone fungicides have obvious effect and fast action speed in controlling the growth and metabolism of microorganisms and preventing the formation of biofilm.



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN METHYLISOTHIAZOLINONE?
*Body Washes/Hand Soaps/Moisturizers
*Cleaners
*Hair Products
• Hair Dyes
• Shampoos
• Conditioners
*Paint
*Pet Care
*Yard Care Products



PREPARATION OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone is prepared by cyclization of cis-N-methyl-3-thiocyanoacrylamide:
NCSCH=CHC(O)NHCH3⟶SCH=CHC(O)NCH3+HCN



WHERE IS METHYLISOTHIAZOLINONE FOUND?
Methylisothiazolinone is a preservative used in personal hygiene products (such as shampoos, lotions, emulsions, and sun screens), and in industrial cooling oils, cutting oils, and paper finishes.
Methylisothiazolinone is also commonly added to household cleaners as a substitute for formaldehyde.
Methylisothiazolinone is a component in Kathon and Grotan preservatives.



WHAT PRODUCTS IS METHYLISOTHIAZOLINONE IN?
Methylisothiazolinone is found in a multitude of products, including those claiming to be “natural”.
The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos.



PHYSICAL and CHEMICAL PROPERTIES of METHYLISOTHIAZOLINONE:
Chemical formula: C4H5NOS
Molar mass: 115.1 g/mol
Appearance: white solid
Cas No: 2682-20-4
Molecular Formula: C4H5NOS
Molecular Weight: 115.15
Appearance: Yellowish transparent liquid
Purity(%): ≥10; 20; 50
pH value: 4.0～7.0
Density (g/ml): ≥1.02
Physical state: Powder with lumps
Color: dark yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: 46,7 - 48,3 °C
Initial boiling point and boiling range: > 130 °C at 16 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: 396 °C at 1.012 hPa
Decomposition temperature: No data available
pH: 2,58 at 50 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water:
log Pow: -0,34 at 30 °C
Bioaccumulation is not expected.
Vapor pressure: 0,0099 hPa at 20 °C
Density: 1,39 g/cm3 at 20 °C
Relative density: 1,39 at 20 °C
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension 68,8 mN/m at 1g/l at 19,5 °C
Dissociation constant > 2,81 at 21 °C



FIRST AID MEASURES of METHYLISOTHIAZOLINONE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLISOTHIAZOLINONE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of METHYLISOTHIAZOLINONE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLISOTHIAZOLINONE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Body Protection:
Acid-resistant protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P3
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLISOTHIAZOLINONE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Air sensitive.
Store under inert gas.



STABILITY and REACTIVITY of METHYLISOTHIAZOLINONE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
2-Methyl-1,2-thiazol-3(2H)-one
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-one
Methylisothiazolinone
2-Methyl-4-Isothiazolin-3-one
2-Methyl-3-isothiazolone
2-Methylisothiazol-3-one
2-Methyl-2H-isothiazol-3-one
2-Methyl-4-isothiazolin-3-one
2-Methyl-3(2H)-isothiazolone
Methylisothiazolinone (MI, MIT)
2-Methyl-4-isothiazolin-3-one
2-Methyl-2,3-dihydroisothiazol-3-one
2-methyl- 3 (2H) -isothiazolone
2-methyl-2H-isothiazol-3-one
2-methyl-3 (2H) -isothiazolone
2-methyl-4-isothiazolin-3-one
3 (2H) -isothiazolone, 2-methyl-
3 (2H) isothiazolone, 2methyl
2-methyl-3 (2H) -isothiazolone
2-methyl-4-isothiazolin-3-one
2-methyl-4-isothiazolin-3-one
2-methyl-2H-isothiazol-3-one
2-Methylisothiazol-3(2H)-one
Neolone 950 preservative
OriStar MIT
Microcare MT
MI
MIT

METHYLISOTHIAZOLINONE = 2-METHYL-4-ISOTHIAZOLIN-3-ONE = MI = MIT


CAS Number: 2682-20-4
EC Number: 220-239-6
MDL number: MFCD01742315
Empirical Formula (Hill Notation): C4H5NOS


Methylisothiazolinone is a clear, colourless liquid that is soluble in water.
Methylisothiazolinone enhances the safety and shelf-life of products by preventing the growth of bacteria and yeasts.
Without preservatives like Methylisothiazolinone, products could start to smell unpleasant, change colour or grow moulds which can produce toxins which are harmful to health.


Methylisothiazolinone, also known as MI, is added to substances containing water to stop the growth of microorganisms.
Methylisothiazolinone simply prevents the product from rotting and aging.
Methylisothiazolinone is commonly found in cosmetics, hygiene products, and other body care products.
Methylisothiazolinone, MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3.


Methylisothiazolinone is a white solid.
Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
Methylisothiazolinone (MI) is a preservative that' super efficient against bacteria at surprisingly low concentrations.


Methylisothiazolinone is a component in Kathon and Grotan preservatives.
Methylisothiazolinone is a colorless,clear liquid with amild odor that is completely soluble in water; mostly soluble in acetonitrile, methanol, and hexane; and slightly soluble in xylene.
Methylisothiazolinoneis a heterocyclic organic compound used as a preservative in cosmetics and personal care products in concentrations up to 0.01%.
Methylisothiazolinone is a 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom.


Methylisothiazolinone has a role as an antifouling biocide, an antimicrobial agent and an antifungal agent.
Methylisothiazolinone is a powerful biocide.
That means Methylisothiazolinone’s a chemical substance that can control or kill harmful microorganisms.
Methylisothiazolinone works well as a preservative in products like shampoo and body care products, helping them to last a long time on the shelf and in your bathroom cabinets without becoming contaminated with unwanted bugs, bacteria, and fungi.


Methylisothiazolinone belongs to a group of similar compounds called “isothiazolinones,” which also include the following chemicals:
*Chloromethylisothiazolinone (CMIT)
*Benzisothiazolinone (BIT)
*Octylisothiazolinone (OIT)
*Dichlorooctylisothiazolinone (DCOIT)


Methylisothiazolinone (MI) is an isothiazolinone-derived biocide used for controlling microbial growth in industrial and household products, often in a mixture with 5-chloro-2-methyl-3-isothiazolone (MCI).
Methylisothiazolinone is active against Gram-positive and Gram-negative bacteria, fungi, and yeast with MIC values of 0.0045, 0.0015, >0.01, and 0.0065% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively, when used alone.
MIC values are 7 to 200-fold lower when Methylisothiazolinone is used in combination with MCI.


Methylisothiazolinonedecreases neurite outgrowth of rat cortical neurons when used at concentrations of 0.1-3 μM and inhibits Src family kinases in cell-free assays.
There are no known interactions with other ingredients.
Methylisothiazolinone (MIT) is a chemical substance that is effective in eliminating and controlling the growth of potentially harmful bacteria,.


Methylisothiazolinone (MI) is a preservative.
Methylisothiazolinone (also called 2-methyl-4-isothiazolin-3-one), is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone is a synthetic chemical used in consumer products for its antimicrobial properties.
Methylisothiazolinone is most often applied to cleaning products as a synthetic preservative.


Methylisothiazolinone was first used in Europe in the 1970s and the United States in the 1980s.
The original European recommendation was to use 0.003% concentration or 30 parts per million (ppm).
In 2000, companies started using methylisothiazolinone in industrial products.
By 2005 some cosmetic companies were using as much as 50 to 100 ppm.



USES and APPLICATIONS of METHYLISOTHIAZOLINONE:
Methylisothiazolinone (MCI) is a preservative that’s active against bacteria, yeast, and fungi.
Methylisothiazolinone’s used in the manufacture of water-based cosmetics and personal care products.
Methylisothiazolinone, better known by the acronym MIT, is used as a synthetic preservative in cosmetic products.
Methylisothiazolinone has been used as a substitute for parabens in so-called "paraben-free" products by a number of brands.


Methylisothiazolinone, or MIT as it is sometimes known, is a preservative used in cosmetics and beauty products.
Methylisothiazolinone is a powerful biocide, or “chemical substance capable of killing living organisms, usually in a selective way.
Biocides are a general term that includes antimicrobial, germicide, antibiotic, and antifungal.
Ultimately, Methylisothiazolinone is used to prevent a wide variety of bacteria and fungi from growing in cosmetics and beauty products, most often in shampoo.


Methylisothiazolinone is only approved for use in rinse-off formulas and at low concentrations.
Methylisothiazolinone is used to control slime-forming bacteria, fungi, and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems.
And Methylisothiazolinone is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other specialty industrial products as a preservative.


Methylisothiazolinone is also used to control the growth of mold, mildew, and sapstain on wood products.
Methylisothiazolinone is generally recommended for use only in rinse-off and leave-on cosmetic products (maximum concentration of 100 ppm) as preservative such as shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps, and detergents.


Even though MIT doesn't have direct benefits for hair, it does have a number of benefits in a product formulation.
Methylisothiazolinoneprotects products at a very low-use level.
Methylisothiazolinone's also water soluble, making it very easy to mix in, It's also stable over a broad pH range, making it suitable for many types of formulas like shampoos and conditioners.
Methylisothiazolinone was initially used occupationally, in paints, adhesives/glues and cleaners etc, as a mixture with methylchloroisothiazolinone (MCI).


Since 2005, it has been widely used in cosmetics and household products, such as moist wipes, shampoos, cleaners and liquid laundry products.
Methylisothiazolinone is used as a biocide and preservative in cosmetics, paints, and glues.
Methylisothiazolinone is used as an antimicrobial in cosmetics, hygiene products, paints, emulsions, cutting oils, paper coatings, and water storage and cooling units.
Methylisothiazolinone is used as a biocide in textile production.


Methylisothiazolinone is used as a preservative in pesticide products.
Methylisothiazolinone is used as a biocide in pulp/paper mills, industrial process and cooling water systems, oil field operations, and air cleaner systems, and as a preservative in adhesives, coatings, fuels, metalworking fluids, resin emulsions, paints, and wood products.
Methylisothiazolinone is a biocide and is used to control microbial growth in water containing solutions.


Methylisothiazolinone is used for controlling microbial growth in water-containing solutions.
Methylisothiazolinone is typically used in a formulation with 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT), in a 3:1 mixture (CMIT:MIT) sold commercially.
In addition, Methylisothiazolinone serves as an antimicrobial agent in latex adhesives and in paper coatings that also contact food.
Methylisothiazolinone, along with other isothiazolinones, is a biocide widely used as a preservative in personal care products.


Methylisothiazolinone is also used in many industrial processes, such as paint and paper manufacturing, metalworking, mining, and sanitizing.
Methylisothiazolinone is a widely-used preservative.
Methylisothiazolinone is used preservative to keep home and personal care products in good condition: without them, they could be spoiled by bacteria, yeasts and moulds.


Methylisothiazolinone is a common preservative used in the personal care industry.
Methylisothiazolinone is also used, for example, in dishwashing liquids, liquid cleaning products, paint, glue, etc.
Methylisothiazolinone can be found in liquid construction products such as Ingredients will also be disclosed in such products.
Methylisothiazolinone functions as a biocide and preservative within the group of isothiazolinones and is widely used in cosmetics, shampoos, soaps and body care products, cooling fluids, etc.


Methylisothiazolinone is used as a preservative that’s generally recommended for use only in rinse-off products such as cleansers or shampoos.
Methylisothiazolinone (MIT) is a preservative that is found in a wide array of liquid cosmetics, personal care products and cleaning products on the market today.
Methylisothiazolinone's function is to inhibit the growth of bacteria.


Methylisothiazolinone is a preservative used in personal hygiene products (such as shampoos, lotions, emulsions, and sun screens), and in industrial cooling oils, cutting oils, and paper finishes. It is also commonly added to household cleaners as a substitute for formaldehyde.
Methylisothiazolinone is also used in air fresheners and may be a preservative component of a product.
Specifically, Methylisothiazolinone can be found in cleansers such as liquid dish soap, liquid laundry soap, all purpose spray cleaners and window cleaning solutions.


Methylisothiazolinone is a isothiazolinone based biocide and preservative used in personal care products.
Methylisothiazolinone is also used for controlling microbial growth in water-c ontaining solution.
Although Methylisothiazolinone may be used in cosmetics and personal care products alone, it is often used as a mixture with Methylchloroisothiazolinone [(MCI).


In cosmetics and personal care products historically, Methylisothiazolinone, or the mixture, Methylisothiazolinone and Methylchloroisothiazolinone, was used in various rinse-off and leave-on formulations including hair products, shampoos, skin care products, bath products, eye and facial makeup, wet wipes and suntan products.
Methylisothiazolinone is a widely used preservative and biocide.


Methylisothiazolinone hydrochloride is an isothiazolinone based biocide and preservative used in personal care products.
Methylisothiazolinone is also used for controlling microbial growth in water-containing solutions.
Methylisothiazolinone is used to studying the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites.


Methylisothiazolinone hydrochloride (Methylisothiazolinone hydrochloride) is a common preservative used in industrial products, owing to its strong biocide effect.
You’ll find Methylisothiazolinone and chemicals like it at low concentrations in “rinse-off” products like shampoos, conditioners, hair colors, body washes, laundry detergents, liquid hand soaps, bubble bath, hand dishwashing soaps, and shampoo/conditioner combinations.


Methylisothiazolinone is a preservative used in personal care products to stop fungus, bacteria and other microbes from growing in water solutions.
Methylisothiazolinone helps maintain product quality and performance over time.
Methylisothiazolinone is a biocide, a chemical substance that controls or kills microorganisms.


Methylisothiazolinone is often found in antibacterial and cleaning products and is used as a preservative.
Methylisothiazolinone is a synthetic ingredient that is commonly found in many household cleaners, including many so called "green cleaners" despite existing science that proves it causes harm to human health and aquatic life.
Methylisothiazolinone (MI or MIT) is part of a family of chemical preservatives which also includes benzisothiazolinone (BIT or BI), methylchloroisothiazolinone (MCI, CMI or CMIT), and octylisothiazolinone (OIT or OI).


Isothiazolinones are often used to extend a product’s shelf life and protect you against exposure to bacteria and fungi by inhibiting the growth of those organisms (collectively known as microbes or as we like to call them “bugs”).
Methylisothiazolinone was first registered in the U.S. in 1977 and initially used in paints, adhesives/glues and cleaners, especially in a mixture with methylchloroisothiazolinone.


Methylisothiazolinone is a preservative that can also be found in shampoos, skin care products and makeup.
Methylisothiazolinone helps maintain product quality and performance over time.
Methylisothiazolinone is used to extend a product’s shelf life and protect consumers against exposure to bacteria and mold by inhibiting the growth of those organisms.


Methylisothiazolinone is Preservative that’s generally recommended for use only in rinse-off products such as cleansers or shampoos.
Methylisothiazolinone or MIT is a preservative used in many consumer goods including cosmetic products, to preserve product quality and ensure consumer safety by preventing the growth of microbes.
Methylisothiazolinone is used to protect products from contamination by potentially pathogenic microbes (fungi and bacteria).


Since 2005, they have become widely used in cosmetics and household products.
Methylisothiazolinone is a widely-used preservative in many personal care products, specifically many hair care products.
Methylchloroisothiazolinone is a chemical used in skin care products, household cleaners, and industrial products as a preservative. It is usually mixed with methylisothiazolinone and the combination is sometimes called Kathon CG or Euxyl K 100.


-Methylisothiazolinone’s also used in industrial processes, including the manufacture of:
*paper coatings
*detergents
*paints
*glue
*cutting oils


-Hair Type Considerations:
Methylisothiazolinone can be used by all hair types.
Methylisothiazolinone is more important to be conscious of any allergies or skin you might have before using products containing the ingredient.



FUNCTIONS OF METHYLISOTHIAZOLINONE:
*Preservative:
Inhibits the development of micro-organisms in cosmetic products



WHAT PRODUCTS CAN CONTAIN METHYLISOTHIAZOLINONE?
*Household cleaning products
*Foundations/concealer
*Sunscreens, moisturizers, creams/lotions/gels
*Detergents/cleaners
*Bronzers/self-tanners
*Shampoo/conditioners
*Fabric softeners/ washing detergents
*Eye shadows, mascaras, makeup removes
*Bubble baths
*Polishes
*Soaps/hand washes/body washes
*Baby wet wipes



WHAT ARE SOME PRODUCTS THAT MAY CONTAIN METHYLISOTHIAZOLINONE?
*Body Washes/Hand Soaps/Moisturizers
*Cleaners
*Hair Products
• Hair Dyes
• Shampoos
• Conditioners
*Paint
*Pet Care
*Yard Care Products



BENEFITS OF METHYLISOTHIAZOLINONE FOR HAIR:
MIT does not have any benefits specifically for your hair.
Methylisothiazolinone won't make it shiny, more manageable, thicker, or stronger.
Methylisothiazolinone is strictly used in cosmetics as a preservative and bacteria-inhibitor, which is obviously an important thing we all want in a product we're keeping in a warm, damp place like the bathroom.



WHAT PRODUCTS IS METHYLISOTHIAZOLINONE IN?
Methylisothiazolinone is found in a multitude of products, including those claiming to be “natural”.
The list includes cleaning products, detergents, lotions, sunscreens, shampoos, conditioners, hair coloring, body washes, mascara, shaving cream, make-up remover, liquid soaps, and baby products including wipes, lotions and shampoos.



PREPARATION OF METHYLISOTHIAZOLINONE:
Methylisothiazolinone is prepared by cyclization of cis-N-methyl-3-thiocyanoacrylamide:
NCSCH = CHC(O)NHCH3⟶SCH = CHC(O)NCH3 + HCN



WHY IS METHYLISOTHIAZOLINONE USED IN COSMETICS AND PERSONAL CARE PRODUCTS?
Why is it used in cosmetics and personal care products?
Methylisothiazolinone and Methylchloroisothiazolinone (MCI) are preservatives.
Preservatives are natural or man-made ingredients designed to help ensure the safety and quality of products by protecting them against the growth of microorganisms during storage and, most importantly, during use by consumers.
Any product that contains water is particularly susceptible to being spoiled by microbial growth, causing problems such as discoloration, unpleasant odors or breakdown.
Under certain conditions, microorganisms can even grow to potentially harmful levels.
Preservatives are designed to help prevent these problems.



PHYSICAL and CHEMICAL PROPERTIES of METHYLISOTHIAZOLINONE:
Chemical formula: C4H5NOS
Molar mass: 115.1 g/mol
Appearance: white solid
Physical state Powder with lumps
Color: dark yellow
Odor: No data available
Melting point/freezing point:
Melting point/range: 46,7 - 48,3 °C
Initial boiling point and boiling range: > 130 °C at 16 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: 396 °C at 1.012 hPa
Decomposition temperature: No data available

pH: 2,58 at 50 g/l at 25 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: soluble
Partition coefficient: n-octanol/water:
log Pow: -0,34 at 30 °C
Bioaccumulation is not expected.
Vapor pressure: 0,0099 hPa at 20 °C
Density: 1,39 g/cm3 at 20 °C
Relative density: 1,39 at 20 °C
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none

Other safety information:
Surface tension: 68,8 mN/m at 1g/l at 19,5 °C
Dissociation constant: > 2,81 at 21 °C
Melting point: 254-256 °C(lit.)
Boiling point: bp0.03 93°
Density: 1.25 (14% aq.)
vapor pressure: storage temp.: 2-8°C
solubility: Chloroform, Ethyl Acetate
pka: -2.03±0.20(Predicted)
form: neat
color: Yellow
Water Solubility: 489g/L at 20℃



FIRST AID MEASURES of METHYLISOTHIAZOLINONE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
Give water to drink (two glasses at most).
Seek medical advice immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of METHYLISOTHIAZOLINONE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully.
Dispose of properly.



FIRE FIGHTING MEASURES of METHYLISOTHIAZOLINONE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of METHYLISOTHIAZOLINONE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Use tightly fitting safety goggles
*Body Protection:
Acid-resistant protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of METHYLISOTHIAZOLINONE:
-Precautions for safe handling:
*Advice on safe handling:
Work under hood.
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store under inert gas.



STABILITY and REACTIVITY of METHYLISOTHIAZOLINONE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
2-Methyl-1,2-thiazol-3(2H)-one
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-one
2-METHYL-4-ISOTHIAZOLIN-3-ONE
2-METHYL-3(2H)-ISOTHIAZOLONE
2-Methylisothiazol-3(2H)-one
2-Methyl-4-isothiazolin-3-on
METHYLISOTHIAZOLONE
Casson preservatives
2-methyl-2H-isothiazol-3-one
2-METHYL-4-ISOTHIAZOLINE-3-ONE
2-Methyl-3-isothiazolone
2-Methyl-2H-isothiazole-3-one
2-Methyl-3-isothiazolone
2-Methyl-4-isothiazoline-3-ketone
2-Methyl-4-isothiazoline-3-one
N-Methylisothiazolin-3-one
2-Methyl-3(2H)-isothiazolone
2-Methyl-4-isothiazolin-3-one
2-Methyl-2H-isothiazol-3-one
2-Methyl-4-isothiazolin-3-one calcium chloride
3(2H)-Isothiazolone, 2-methyl-
2-Methyl-2,3-dihydroisothiazol-3-one
Neolone 950
2-Methylisothiazol-3(2H)-one
UN3261
Methylisothiazolinone
3(2H)-Isothiazolone, 2-methyl-
2-Methyl-2H-isothiazol-3-one
2-Methyl-4-isothiazolin-3-one
2-Methyl-3(2H)-isothiazolone
MI
MIT
2-Methyl-4-isothiazoline-3-one
Neolone 950 preservative
OriStar MIT
Microcare MT

Methylisothiazolinone (MI), is a powerful synthetic biocide and preservative within the group of isothiazolinones.
Methylisothiazolinone (MI) is used to control slime-forming bacteria, fungi, and algae in pulp/paper mills, cooling water systems, oil field operations, industrial process waters, and air washer systems.
And Methylisothiazolinone (MI) is incorporated into adhesives, coatings, fuels, metal working fluids, resin emulsions, paints, and various other specialty industrial products as a preservative.

CAS: 2682-20-4
MF: C4H5NOS
MW: 115.15
EINECS: 220-239-6

Synonyms
1-(4-CHLOROPHENYL)-3-(3,4-DICHLOROPHENYL)UREA;2-METHYL-4-ISOTHIAZOLIN-3-ONE;2-METHYL-4-ISOTHIAZOLINE-3-ONE;2-METHYL-3(2H)-ISOTHIAZOLONE;N-METHYL-3-OXODIHYDRO ISOTHIAZOLE;2-methyl-3(2h)-isothiazolon;Isothiazolone,2-methyl-;Methylisothiazolinone;2682-20-4;2-Methyl-4-isothiazolin-3-one;Methylisothiazolinone;2-Methyl-3(2H)-isothiazolone;2-methylisothiazol-3(2h)-one;2-Methyl-4-isothiazoline-3-one;3(2H)-Isothiazolone, 2-methyl-;N-Methyl-3-oxodihydroisothiazole;N-METHYL-3-OXODIHYDRO ISOTHIAZOLE;2-methyl-3-isothiazolone;2-METHYL-2H-ISOTHIAZOL-3-ONE;MIT;2-methyl-1,2-thiazol-3(2H)-one;229D0E1QFA;DTXSID2034259;CHEBI:53620;2682-20-4 (free base);MFCD01742315;Neolone;Caswell No. 572A;Microcare MT;Kordek MLX;EINECS 220-239-6;MIT (biocide);Acticide M 10;Acticide M 20bv;Bestcide 600;Kordek 50;Kordek 50C;2-methyl-1,2-thiazol-3-one;Kordek 573F;Kathon CG 243;n-methylisothiazolin-3-one;UNII-229D0E1QFA
;Neolone 950; 2-Methyl-4-isothiazolin-3-one; 2-Methylisothiazol-3-one;HSDB 8200;MIT 950;MT 10;2-Methyl-4-isothiazoline-3-ketone;KB 838;2-Methyl-4-isothiazolin-3-one (MI);2-methyl-4-isothiazolinone;SCHEMBL17863;SCHEMBL113898;Methylisothiazolinone free base;CHEMBL1620780;DTXCID0014259;METHYLISOTHIAZOLINONE [II];METHYLISOTHIAZOLINONE [MI];2-Methyl-4-isothiazolin-3-one 100 microg/mL in Acetonitrile;2-Methyl-3(2H)-isothiazolone #;METHYLISOTHIAZOLINONE [VANDF];Tox21_303814;BBL104136;METHYLISOTHIAZOLINONE [MART.];STL557951;AKOS007930246;AM84857;CS-W011236;HY-W010520;2-Methyl-4-isothiazolin-3-one, 95%;NCGC00357093-01;CAS-2682-20-4;2-methyl-2,3-dihydro-1,2-thiazol-3-one;DB-005250;NS00003875;F21330;EN300-1708622;Q423870;2-Methyl-4-isothiazolin-3-one, analytical standard

Methylisothiazolinone (MI) is also used to control the growth of mold, mildew, and sapstain on wood products.
Methylisothiazolinone (MI) is generally recommended for use only in rinse-off and leave-on cosmetic products (maximum concentration of 100 ppm) as preservative such as shampoo, conditioner, hair color, body wash, lotion, sunscreen, mascara, shaving cream, baby lotion, baby shampoo, hairspray, makeup remover, liquid soaps, and detergents.
Nevertheless, methylisothiazolinone is allergenic.
Methylisothiazolinone (MI) is reported that methylisothiazolinone in rinse-off products causes allergic contact dermatitis.
Methylisothiazolinone (MI) is an isothiazolinone-derived biocide used for controlling microbial growth in industrial and household products, often in a mixture with 5-chloro-2-methyl-3-isothiazolone (MCI).
Methylisothiazolinone (MI) is active against Gram-positive and Gram-negative bacteria, fungi, and yeast with MIC values of 0.0045, 0.0015, >0.01, and 0.0065% (w/w) for S. aureus, P. aeruginosa, A. niger, and C. albicans, respectively, when used alone.

MIC values are 7 to 200-fold lower when Methylisothiazolinone (MI) is used in combination with MCI.
Methylisothiazolinone (MI) decreases neurite outgrowth of rat cortical neurons when used at concentrations of 0.1-3 μM and inhibits Src family kinases in cell-free assays.
Methylisothiazolinone (MI), alone and as a mixture with MCI, can elicit contact sensitization.
Methylisothiazolinone (MI) is a 1,2-thazole that is 4-isothiazolin-3-one bearing a methyl group on the nitrogen atom.
Methylisothiazolinone (MI) is a powerful biocide and preservative and is the minor active ingredient in the commercial product Kathon(TM).
Methylisothiazolinone (MI) has a role as an antifouling biocide, an antimicrobial agent and an antifungal agent.
Methylisothiazolinone (MI), MIT, or MI, is the organic compound with the formula S(CH)2C(O)NCH3.

Methylisothiazolinone (MI) is a white solid.
Isothiazolinones, a class of heterocycles, are used as biocides in numerous personal care products and other industrial applications.
Methylisothiazolinone (MI) and related compounds have attracted much attention for their allergenic properties, e.g. contact dermatitis.
Methylisothiazolinone (MI) and Methylchloroisothiazolinone (CMIT) may be hard to pronounce, but they can be even harder on the body.
These common preservatives are found in many liquid personal care products, and have been linked to lung toxicity, allergic reactions, and possible neurotoxicity.

Methylisothiazolinone (MI) is a synthetic preservative that is commonly used in personal care products and cosmetics due to its ability to inhibit bacterial and fungal growth.
Methylisothiazolinone (MI) extends the shelf life of products and is specifically beneficial for water-based cosmetics.
However, Methylisothiazolinone (MI) comes at a cost - Methylisothiazolinone has garnered attention for potential skin sensitization issues, leading to regulatory scrutiny and label warnings.
In high concentrations, Methylisothiazolinone (MI) can cause skin burns and severe allergies.
Therefore, a lot of personal care brands are opting for alternatives such as Phenoxyethanol in leave-on products.
Other names of Methylisothiazolinone (MI) include Neolone 950 preservative, 2-methyl-4-isothiazoline-3-one, MI, Microcare MT, and OriStar MIT.

Methylisothiazolinone (MI) is a liquid biocide with outstanding advantages such as rapid inhabitation of growth and macromolecule synthesis, broad spectrum activity, effective at low concentration and against biofilm as well as a wide pH range, biodegradable non-persistent in the environment, non-surface activity, infrequent dosing, easily deactivated, compatibility, low toxicity, water soluble, non-foaming, cost effectiveness etc.
The active ingredient is a mixture of two isothiazolines.
Methylisothiazolinone (MI) is ideally suited to meet the requirement of an industrial water treatment biocide for bacteria, fungi and algae paper mill slimicide.

Methylisothiazolinone (MI) Chemical Properties
Melting point: 254-256 °C(lit.)
Boiling point: bp0.03 93°
Density: 1.25 (14% aq.)
Vapor pressure: <0.1 mm Hg ( 25 °C)
Storage temp.: 2-8°C
Solubility: Chloroform, Ethyl Acetate
pka: -2.03±0.20(Predicted)
Form: Solid
Color: Yellow
Water Solubility: 489g/L at 20℃
BRN: 606203
InChIKey: BEGLCMHJXHIJLR-UHFFFAOYSA-N
LogP: -0.486 at 20℃
CAS DataBase Reference: 2682-20-4(CAS DataBase Reference)
NIST Chemistry Reference: Methylisothiazolinone (MI) (2682-20-4)
EPA Substance Registry System: Methylisothiazolinone (MI) (2682-20-4)

Methylisothiazolinone (MI) is a colorless,clear liquid with amild odor that is completely soluble in water; mostly soluble in acetonitrile, methanol, and hexane; and slightly soluble in xylene.
Methylisothiazolinone (MI) is a heterocyclic organic compound used as a preservative in cosmetics and personal care products in concentrations up to 0.01%.

Uses
Methylisothiazolinone (MI), or MIT as it is sometimes known, is a preservative used in cosmetics and beauty products.
Methylisothiazolinone (MI) is a powerful biocide, or “chemical substance capable of killing living organisms, usually in a selective way.”Biocides are a general term that includes antimicrobial, germicide, antibiotic, and antifungal.
Ultimately, Methylisothiazolinone (MI) is used to prevent a wide variety of bacteria and fungi from growing in cosmetics and beauty products, most often in shampoo.
Methylisothiazolinone (MI) is only approved for use in rinse-off formulas and at low concentrations.
Methylisothiazolinone (MI) is a isothiazolinone based biocide and preservative used in personal care products.

Methylisothiazolinone (MI) is also used for controlling microbial growth in water-c ontaining solution.
Methylisothiazolinone (MI) is a preservative compound widely used in cosmetics.
Methylisothiazolinone (MI) is a contact allergen and sensitiser.
Methylisothiazolinone (MI) has recently been identified as a neurotoxin that can damage nerve endings with repeated exposure.
Methylisothiazolinone (MI) or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products.
Methylisothiazolinone (MI) is also used in industrial applications as a preservative and antifouling agent.

Preparation
Methylisothiazolinone (MI) is prepared by cyclization of
cis-N-methyl-3-thiocyanoacrylamide: NCSCH=CHC(O)NHCH3?SCH=CHC(O)NCH3+HCN

Preparation
Methylisothiazolinone (MI) is prepared by cyclization of cis-N-methyl-3-thiocyanoacrylamide:

Hazard
Methylisothiazolinone (MI) is allergenic and cytotoxic, and this has led to some concern over its use.
A report released by the European Scientific Committee on Cosmetic Products and Non-food Products Intended for Consumers (SCCNFP) in 2003 also concluded that insufficient information was available to allow for an adequate risk assessment analysis of Methylisothiazolinone (MI).

Side effects
Early on, dermatitis may occur only on part of the exposed skin.
Common patterns include: hand dermatitis，perianal dermatitis, perivulval dermatitis, napkin dermatitis, facial dermatitis, eyelid swelling, and scalp dermatitis.
Later, more extensive and severe whole-body contact dermatitis may occur in very sensitive people.

Methylparaben is a pheromone in wolves produced during estrus associated with the behavior of alpha male wolves preventing other males from mounting females in heat.
Methylparaben resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with methanol.
Methylparaben is the most frequently used antimicrobial preservative in cosmetics.

CAS Number: 99-76-3
Molecular Formula: C8H8O3
Molecular Weight: 152.15
EINECS Number: 202-785-7

Synonyms: Methylparaben, METHYLPARABEN1, 99-76-3, Methyl paraben, Methyl p-hydroxybenzoate, Nipagin, Methyl parahydroxybenzoate, Tegosept M, Moldex, Maseptol, Preserval M, Methaben, Metoxyde, Preserval, Metaben, Paridol, Septos, Solbrol, Methyl butex, p-Hydroxybenzoic acid methyl ester, p-Methoxycarbonylphenol, Benzoic acid, 4-hydroxy-, methyl ester, Methyl chemosept, p-Carbomethoxyphenol, 4-Hydroxybenzoic acid methyl ester, Methyl parasept, Nipagin M, Aseptoform, Methylben, Abiol, Methyl-p-hydroxybenzoate, Methyl p-oxybenzoate, Solbrol M, 4-(Methoxycarbonyl)phenol, 4-Hydroxybenzoic acid, methyl ester, FEMA No. 2710, Killitol, p-Hydroxybenzoic methyl ester, FEMA Number 2710, Methyl ester of p-hydroxybenzoic acid, p-Oxybenzoesauremethylester, Methylparaben e218, NSC 3827, MFCD00002352, CCRIS 3946, Benzoic acid, p-hydroxy-, methyl ester, HSDB 1184, Methyl paraben (e218), methyl 4- hydroxybenzoate, Methyl-d3Paraben, UNII-A2I8C7HI9T, NSC-3827, p-Hydroxybenzoic acid, methyl ester, EINECS 202-785-7, A2I8C7HI9T, EPA Pesticide Chemical Code 061201, NSC-406127, BRN 0509801, methyl hydroxybenzoate, DTXSID4022529, INS number 218, CHEBI:31835, Methylis hydroxybenzoas, AI3-01336, INS-218, 4-HYDROXY-BENZOIC ACID METHYL ESTER, Methylester kyseliny p-hydroxybenzoove, E218, CHEMBL325372, DTXCID402529, INS NO.218, E-218, NSC3827, EC 202-785-7, 4-Hydroxybenzoic acid-methyl ester, NCGC00159376-02, NCGC00159376-04, E 218, METHYLPARABEN (II), METHYLPARABEN [II], WLN: QR DVO1, METHYLPARABEN (USP-RS), METHYLPARABEN [USP-RS], Methylparaben [USAN], Caswell No. 573PP, 4-Hydroxybenzoic acid-methyl ester 1000 microg/mL in Acetonitrile, METHYL HYDROXYBENZOATE (MART.), METHYL HYDROXYBENZOATE [MART.], CAS-99-76-3, SMR000036660, METHYL PARAHYDROXYBENZOATE (EP MONOGRAPH), METHYL PARAHYDROXYBENZOATE [EP MONOGRAPH], METHYL SALICYLATE IMPURITY C (EP IMPURITY), METHYL SALICYLATE IMPURITY C [EP IMPURITY], p-Oxybenzoesauremethylester [German], Methylparaben [USAN:NF], PROPYL HYDROXYBENZOATE IMPURITY B (EP IMPURITY), PROPYL HYDROXYBENZOATE IMPURITY B [EP IMPURITY], Metagin, METHYL4-HYDROXYBENZOATE, Lexgard M, Paraben M, Methylester kyseliny p-hydroxybenzoove [Czech], (Methyl Paraben), Methylparaben, NF, Methylparaben, FCC, 4-carbomethoxyphenol, Methylparaben (NF), Methylparaben (TN), Solparol (Salt/Mix), methyl 4-hydoxybenzoate, methyl 4 hydroxybenzoate, methyl 4-hydroxylbenzoate, methyl 4-hydroxy-benzoate, methyl-4-hydroxy-benzoate, Methyl 4-?Hydroxybenzoate, METHYLPARABEN [MI], Preserval MS (Salt/Mix), bmse010009, methyl (4-hydroxy)benzoate, METHYLPARABEN [FCC], cid_7456, SCHEMBL4440, isLeaf Tattoo Eyebrow Brown, METHYLIS HYDROXYBENZOAS [WHO-IP LATIN], D01400, Methylparaben, USP, 98.0-102.0%, A846079, Q229987, Q-200479, Methylparaben, SAJ first grade, >=98.0%, Methylparaben, tested according to Ph.Eur., Z19674820, F1908-0119, Methylparaben, BioXtra, >=99.0% (titration), Methylparaben, certified reference material, TraceCERT(R), Methylparaben, ReagentPlus(R), >=99.0%, crystalline, Methylparaben, United States Pharmacopeia (USP) Reference Standard, InChI=1/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H, Methylparaben, BioReagent, suitable for insect cell culture, Methyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard, Methylparaben, Pharmaceutical Secondary Standard; Certified Reference Material

Methylparaben is a pheromone in wolves produced during estrus associated with the behavior of alpha male wolves preventing other males from mounting females in heat.
Methylparaben is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives.
Methylparaben is used as an anti-fungal agent.

Methylparaben is also used as a preservative in foods, beverages and cosmetics.
Methylparaben acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.
Methylparaben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa).

Methylparaben is commonly used as a stable, non-volatile preservative.
Methylparaben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury.
Methylparaben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen.

Methylparaben is a stable, non-volatile compound used as an antimicrobial preservative in foods, drugs and cosmetics.
The physiologic effect of Methylparaben is by means of increased histamine release, and cell-mediated immunity.
Methylparaben is widely used as a preservative in the cosmetic, pharmaceutical, and food industries.

Methylparaben helps prevent the growth of bacteria, mold, and yeast in various products, extending their shelf life.
Methylparaben is often used alongside other parabens for enhanced preservative efficacy.
Methylparaben is listed on ingredient labels under various names, including Methylparaben, METHYLPARABEN, and E218.

While it has been widely used, there has been some debate and research regarding the safety of parabens in cosmetic and personal care products, leading to the development of alternative preservatives in some formulations.
Methylparaben, also called methyl paraben or nipagin, comprises the ester of p-hydroxybenzoic acid.
Methylparaben is present naturally in cloudberry, white wine and bourbon vanilla.

Methylparaben has antimicrobial and antifungal functionality and is commercially used as a preservative in the food, cosmetic and pharmaceutical industry.
Methylparaben has cytotoxic effects on keratinocytes in the presence of sunlight.
Methylparaben upon solar irradiation mediates DNA damage and modulates esterase metabolism resulting in skin damage and favors cancer progression.

Methylparaben has estrogenic functionality and upregulates estrogen-related genes
Methylparaben, isolated from the barks of Tsuga dumosa the methyl ester of p-hydroxybenzoic acid, is a standardized chemical allergen.
Methylparaben sulfate belongs to the class of organic compounds known as phenylsulfates.

Phenylsulfates are compounds containing a sulfuric acid group conjugated to a phenyl group.
Based on a literature review very few articles have been published on Methyl-4-hydroxybenzoate sulfate.
The chemical structure of Methylparaben consists of a benzene ring with a hydroxyl group (-OH) and a methyl ester group (-COOCH3) attached to the para position of the ring.

Methylparaben is known by various common names, including Methylparaben, Methaben, Nipagin M, and Methyl p-hydroxybenzoate.
Methylparaben is widely used as a preservative in cosmetics, skincare products, personal care products, and pharmaceuticals to prevent the growth of microorganisms and increase product shelf life.
Methylparaben is also utilized as a preservative in certain food products.

In pharmaceutical formulations, Methylparaben can be used to preserve the stability of drugs.
Methylparaben, along with other parabens, has been the subject of some research and discussion regarding its safety.
Some studies have suggested potential concerns about parabens being endocrine disruptors, but regulatory bodies have generally deemed them safe for use within established limits.

Regulatory agencies such as the FDA, EFSA, and Cosmetic Ingredient Review (CIR) have reviewed the safety of parabens and set concentration limits for their use in various products.
Due to consumer preferences and evolving regulations, there has been an increased interest in the development and use of alternative preservatives, such as natural or nature-derived preservatives, in some cosmetic and personal care products.

Methylparaben exhibits antimicrobial properties, which is the primary reason for its use as a preservative.
Methylparaben helps prevent the growth of bacteria, yeast, and mold in various products.
Methylparaben is part of a family of parabens, which includes ethylparaben, propylparaben, and butylparaben.

Methylparabens share a similar structure and are used for similar preservative purposes.
Methylparaben is compatible with a wide range of formulations, including creams, lotions, shampoos, and other personal care and cosmetic products.
In the pharmaceutical industry, Methylparaben is sometimes used to preserve the stability of certain medications and prevent microbial contamination.

Regulatory agencies, such as the FDA and the European Commission, have established concentration limits for parabens in cosmetic and personal care products to ensure their safe use.
Methylparaben is also approved for use as a food additive, where it functions as a preservative to extend the shelf life of certain food products.
The safety of Methylparaben has been assessed through various scientific studies, and it has undergone reviews by regulatory bodies to determine its safety for use in cosmetics and other consumer products.

Increased consumer awareness about cosmetic ingredients has led to a demand for transparency in labeling.
Some consumers actively seek products labeled as "paraben-free" due to personal preferences or concerns.
In response to consumer demand, some cosmetic and personal care brands are exploring and using natural or nature-derived preservatives as alternatives to synthetic ones like parabens.

Methylparaben is widely accepted as a preservative in cosmetic and personal care formulations globally.
Methylparaben is use is regulated by various authorities to ensure consumer safety.
Methylparaben is the methyl ester of p-hydroxybenzoic acid.

Methylparaben, commonly known as Methylparaben, is a chemical compound with the molecular formula C8H8O3.
Methylparaben, 99% - one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).
Methylparaben is also called methylparaben.

This paraben is a white crystalline powder or colorless crystals.
Methylparaben is freely soluble in alcohol, ether, and acetone and very slightly soluble in water.
Methylparaben boiling point is 270~280℃.

Methylparaben by Zhejiang Shengxiao Chemicals is a preservative.
Methylparaben is suitable for cosmetics.
Methylparaben occurs naturally in several fruits, particularly in blueberries.

Methylparaben has a role as a plant metabolite, an antimicrobial food preservative, a neuroprotective agent and an antifungal agent.
Methylparaben is produced through the methanol esterification of p-hydroxybenzoic acid in the presence of sulfuric acid.
Methylparaben is slightly soluble in water but easily dissolves in ethanol, ether, acetone, and other organic solvents.

Methylparaben one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).
Methylparaben is a colorless crystalline powder with a faint characteristic odor and a slight burning taste.
One gram can dissolve in 2.5 ml of ethanol, approximately 4 ml of propylene glycol, or 400 ml of water at 25°C or about 50 ml of water at 80°C.

Methylparaben is commonly used as a fungistat in soft drinks, non-leavened bakery products, and other products, with a permissible level of up to 0.1%.
To inhibit Gram-positive bacteria, 1000 to 4000 ppm are required, and its effectiveness increases with decreasing pH, similar to benzoates.
Methylparaben is the methyl ester of 4-hydroxybenzoic acid.

Methylparaben is a white, crystalline powder that is soluble in alcohol and slightly soluble in water.
Methylparaben is a type of paraben.
Methylparabens are chemicals that are often used as preservatives to give products a longer shelf life.

Methylparaben one of the parabens, is a preservative with the chemical formula CH3(C6H4(OH)COO).
Methylparaben is the methyl ester of p-hydroxybenzoic acid.
Methylparaben serves as a pheromone for a variety of insects and is a component of queen mandibular pheromone.

The materials are heated in a glass-lined reactor and distilled under reflux.
The resulting acid is neutralized with caustic soda, then crystallized through cooling.
The crystallized product is centrifuged, washed, dried under vacuum, milled and blended, all in corrosion-resistant equipment to avoid metallic contamination.

Methylparaben is basically a methyl ester of p-hydroxybenzoic acid.
Methylparaben is non-toxic, and non-carcinogenic in nature.
Methylparaben is a stable, non-volatile compound and finds application as an anti-microbial preservative in foods, drugs and cosmetics.

Methylparaben is readily absorbed through the skin and gastrointestinal tract.
Upon hydrolyzation, it is hydrolyzed to p-hydroxybenzoic acid, and the conjugates formed get rapidly excreted in the urine.
Methylparaben serves as a pheromone for a variety of insects and is a component of queen mandibular pheromone.

Melting point: 125-128 °C (lit.)
Boiling point: 298.6 °C
Density: 1,46g/cm
vapor pressure: 0.000005 hPa (20 °C)
refractive index: 1.4447 (estimate)
FEMA: 2710 | METHYL P-HYDROXYBENZOATE
Flash point: 280°C
storage temp.: room temp
solubility: ethanol: soluble0.1M, clear, colorless
pka: pKa 8.15(H2O,t =20.0) (Uncertain)
form: Crystalline Powder
color: White to almost white
PH: 5.8 (H2O, 20°C) (saturated solution)
Odor: odorless or faint char. odor, sl. burning taste
Water Solubility: Slightly soluble in water.
FreezingPoint: 131℃
Merck: 14,6107
BRN: 509801
Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey: LXCFILQKKLGQFO-UHFFFAOYSA-N
LogP: 1.98 at 20℃

Methylparaben is generally considered to be biodegradable, but its presence in the environment has led to discussions about its potential accumulation and environmental impact.
Formulators often use a combination of preservatives to achieve a broad-spectrum antimicrobial effect while minimizing the concentration of each individual preservative.
The packaging of products containing Methylparaben should be carefully chosen to prevent contamination, as preservatives play a crucial role in maintaining the integrity of the product during its shelf life.

Increased consumer awareness about cosmetic ingredients has led to greater scrutiny of preservatives like Methylparaben.
Some consumers actively seek products labeled as "paraben-free" or opt for alternatives perceived as more natural.
The safety and use of Methylparaben are subject to ongoing evaluation by regulatory bodies, and any new scientific findings may influence regulations and industry practices.

Parabens are esters formed by p-hydroxybenzoic acid and an alcohol.
They are largely used as biocides in cosmetics and toiletries, medicaments, or food.
They have synergistic power with other biocides.

Parabens can induce allergic contact dermatitis, mainly in chronic dermatitis and wounded skin.
Methylparaben is soluble in alcohol and acetone but only slightly soluble in water.
Methylparaben demonstrates good stability under normal storage conditions, which contributes to its effectiveness as a preservative.

Methylparaben is often used in combination with other parabens, such as ethylparaben, propylparaben, and butylparaben, to create a broader spectrum of antimicrobial activity.
Methylparaben has been approved for use as a food additive and preservative by regulatory agencies, including the U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA).

Methylparaben should be stored in a well-closed container in a cool, dry place.
Methylparaben is widely accepted in many countries for use in a variety of products, including skincare, haircare, and pharmaceuticals.

Methylparaben is one of the parabens family.
Methylparaben is also listed in the United States Pharmacopeia (USP) and other pharmacopeias as a standard for pharmaceutical formulations.
On ingredient labels, Methylparaben may be listed under its chemical name "Methylparaben," as "METHYLPARABEN," or by its E number "E218."

Methylparaben is widely used globally, and its acceptance as a preservative in various products has led to its inclusion in a wide range of consumer goods.
Ongoing research continues to explore the safety and potential alternatives to parabens in cosmetic and personal care products.
Some companies have opted to formulate products without parabens in response to consumer preferences for "paraben-free" options.

Parabens, including Methylparaben, have been detected in the environment, including in water systems.
Research is ongoing to understand the potential environmental impact of these compounds.
Methylparaben has been in use since the early 20th century and gained popularity for its effectiveness as a preservative in cosmetics and personal care products.

Methylparaben is effective over a wide pH range, making it versatile for use in formulations with varying acidity or alkalinity.
In addition to its antibacterial properties, Methylparaben also exhibits antifungal activity, helping to prevent the growth of mold and yeast in formulations.
Regulatory agencies, such as the Cosmetic Ingredient Review (CIR), have established maximum concentrations for the use of Methylparaben in cosmetic and personal care products to ensure safety.

Storage:
Aqueous solutions of Methylparaben at pH 3–6 may be sterilized by autoclaving at 120°C for 20 minutes, without decomposition.
Aqueous solutions at pH 3–6 are stable (less than 10% decomposition) for up to about 4 years at room temperature, while aqueous solutions at pH 8 or above are subject to rapid hydrolysis (10% or more after about 60 days storage at room temperature);

Uses:
Methylparaben is widely used as a preservative in cosmetics and personal care products, including creams, lotions, shampoos, conditioners, deodorants, and makeup.
Methylparaben helps prevent the growth of bacteria, yeast, and mold, extending the shelf life of these products.
In the pharmaceutical industry, Methylparaben is utilized to preserve the stability of certain medications and prevent microbial contamination.

Methylparaben is commonly found in topical formulations, oral medications, and injectables.
Methylparaben is approved as a food additive, where it functions as a preservative to extend the shelf life of certain food products.
Methylparaben is used in some food items, such as baked goods, beverages, and sauces.

Methylparaben may be used in industrial settings where a preservative is needed to prevent microbial growth in products such as adhesives, lubricants, and cutting fluids.
Some medical and healthcare products, such as ointments, creams, and topical solutions, may contain Methylparaben as a preservative to maintain product integrity.
Methylparaben may be used in laboratories and research settings as a preservative for certain solutions and reagents to prevent contamination.

Methylparaben is often used in combination with other parabens (such as ethylparaben, propylparaben, and butylparaben) to create a synergistic preservative effect, providing a broader spectrum of antimicrobial activity.
This combination enhances the overall efficacy of the preservative system.
In addition to its preservative role, Methylparaben may contribute to the stabilization of formulations.

Methylparaben helps maintain the chemical and physical stability of products over time.
Methylparaben is effective over a range of pH levels, making it versatile for use in various formulations that may have acidic, neutral, or slightly alkaline conditions.
Methylparaben helps prevent the spoilage of cosmetic and personal care products by inhibiting the growth of microorganisms that can lead to changes in color, odor, and
texture.

Methylparaben has received regulatory approval from authorities such as the U.S. Food and Drug Administration (FDA), the European Commission, and other regulatory bodies worldwide for its use as a preservative in cosmetics, pharmaceuticals, and food products.
Due to its solubility in water, Methylparaben is commonly used in water-based formulations, including aqueous solutions, creams, and lotions.
Beyond cosmetics and personal care items, Methylparaben may be present in various consumer goods, including household products, to prevent microbial growth and ensure product longevity.

Methylparaben is compatible with a wide range of ingredients commonly found in cosmetic and personal care formulations, making it a versatile choice for product preservation.
Methylparaben is the ester of methyl alcohol and p-hydroxybenzoic acid, It is a bacteriostatic agent and preservative that was added to local anesthetic agents without vasoconstrictors before 1984 to prevent bacterial growth.

Allergic reactions developed from repeated exposures to parabens led to the removal of this agent from dental anesthetic solutions.
Similar products produced by similar production methods, like ethyl p-hydroxybenzoate (paraben B) and propyl p-hydroxybenzoate (Nepalese c), are also disinfectant preservatives.
Methylparabens are irritating to the skin.

Methylparaben is used as an anti-fungal agent.
Methylparaben is also used as a preservative in foods, beverages and cosmetics.
Methylparaben acts as an inhibitor of growth of molds and to lesser extent bacteria and as a vehicle for ophthalmic solution.

Methylparaben is often used in combination with other parabens, such as ethylparaben, propylparaben, and butylparaben, to create a synergistic preservative effect.
This combination broadens the spectrum of antimicrobial activity.
Methylparaben is effective in preserving aqueous (water-based) solutions, making it suitable for a wide range of formulations where water is a significant component.

Methylparaben exhibits stability over a range of pH levels, making it suitable for use in formulations with varying acidity or alkalinity.
Methylparaben has received regulatory approval for use in cosmetics, personal care products, pharmaceuticals, and food items by various regulatory agencies, including the U.S. FDA, European Commission, and other global authorities.

The primary function of Methylparaben is to prevent microbial spoilage by inhibiting the growth of bacteria, yeast, and mold. This property is crucial for maintaining the safety and quality of various consumer products.
Its solubility in water makes Methylparaben suitable for use in water-based formulations, contributing to its versatility in different types of cosmetic and personal care products.
Methylparaben undergoes stability testing to ensure its effectiveness over the intended shelf life of products.

This is particularly important in formulations where extended stability is required.
Cosmetic and personal care formulators conduct compatibility testing to ensure that Methylparaben does not interfere with the stability or performance of other ingredients in a formulation.
Methylparaben has been in use as a preservative for several decades, and its acceptance in various industries reflects its historical effectiveness and reliability.

Methylparaben and propylparaben are the most common of these. parabens is one of the most commonly used group of preservatives in the cosmetic, pharmaceutical, and food industries.
Parabens provide bacteriostatic and fungistatic activity against a diverse number of organisms, and are considered safe for use in cosmetics, particularly in light of their low sensitizing potential.
An evaluation of preservatives for use in leave-on cosmetic preparations lists parabens among the least sensitizing.

The range of concentrations used in cosmetics varies between 0.03 and 0.30 percent, depending on the conditions for use and the product to which the paraben is added.
Methylparaben is one of the most popular preservatives in beauty products and food items.
According to the National Library of Medicine, the ingredient occurs naturally in a handful of fruits—like blueberries—though it can also be created synthetically.

Methylparaben's found in everything from cream cleansers and moisturizers to primers and foundations and helps these products maintain their effectiveness.
Rabach says that it's chock-full of anti-fungal and antibacterial properties, which work wonders to extend the shelf life of skincare, haircare, and cosmetic products.
Methylparaben is widely used as an antimicrobial preservative in cosmetics, food products, and pharmaceutical formulations; see Table I.

Methylparaben may be used either alone or in combination with other methylparaben is the most frequently used antimicrobial preservative.
The parabens are effective over a wide pH range and have a broad spectrum of antimicrobial activity, although they are most effective against yeasts and molds.
Antimicrobial activity increases as the chain length of the alkyl moiety is increased, but aqueous solubility decreases; therefore a mixture of parabens is frequently used to provide effective preservation.

Preservative efficacy is also improved by the addition of propylene glycol (2–5%), or by using parabens in combination with other antimicrobial agents such as imidurea.
Owing to the poor solubility of the parabens, paraben salts (particularly the sodium salt) are more frequently used in formulations. However, this raises the pH of poorly buffered formulations.
Methylparaben together with propylparaben (0.02%) has been used for the preservation of various parenteral pharmaceutical formulations;

Methylparaben is an anti-fungal agent often used in a variety of cosmetics and personal-care products.
Methylparaben is also used as a food preservative and has the E number E218.

Methylparaben is commonly used as a fungicide in Drosophila food media at 0.1%.
To Drosophila, Methylparaben is toxic at higher concentrations, has an estrogenic effect (mimicking estrogen in rats and having anti-androgenic activity), and slows the growth rate in the larval and pupal stages at 0.2%.

Safety Profile:
Methylparaben and other parabens are widely used as antimicrobial preservatives in cosmetics and oral and topical pharmaceutical formulations.
Although parabens have also been used as preservatives in injections and ophthalmic preparations, they are now generally regarded as being unsuitable for these types of formulations owing to the irritant potential of the parabens.

These experiences may depend on immune responses to enzymatically formed metabolites of the parabens in the skin.
Unexpectedly, preparations containing parabens may be used by patients who have reacted previously with contact dermatitis provided they are applied to another, unaffected, site.
This has been termed the paraben paradox.

Concern has been expressed over the use of methylparaben in infant parenteral products because bilirubin binding may be affected, which is potentially hazardous in hyperbilirubinemic neonates.
There is controversy about whether methylparaben or propylparabens are harmful at concentrations typically used in body care or cosmetics.
Methylparaben and propylparaben are considered generally recognized as safe (GRAS) by the USFDA for food and cosmetic antibacterial preservation.

Methylparabenis readily metabolized by common soil bacteria, making it completely biodegradable.
Methylparaben is readily absorbed from the gastrointestinal tract or through the skin.
Methylparaben is hydrolyzed to p-hydroxybenzoic acid and rapidly excreted in urine without accumulating in the body.

Acute toxicity studies have shown that Methylparaben is practically non-toxic by both oral and parenteral administration in animals.
In a population with normal skin, Methylparaben is practically non-irritating and non-sensitizing; however, allergic reactions to ingested parabens have been reported.
A 2008 study found no competitive binding for human estrogen and androgen receptors for Methylparaben, but varying levels of competitive binding were seen with butyl- and isobutyl-paraben.

METHYLPROPANEDIOL, N° CAS : 2163-42-0, Nom INCI : METHYLPROPANEDIOL. Nom chimique : 2-Methyl-1,3-propanediol. N° EINECS/ELINCS : 412-350-5. Ses fonctions (INCI), Solvant : Dissout d'autres substances

SYNONYMS Methyltrimethoxysilane;MTMS;HD-119;Z 6070;CM9100;A-1630;DC Z-6070;silanea-163;Dynasylan MTMS;TrimethoxymethyL;unioncarbidea-163 cas no: 1185-55-3

Methylpyrrolidone is an aprotic solvent with a wide range of applications: petrochemical processing, surface coating, dyes and pigments, industrial and domestic cleaning compounds, and agricultural and pharmaceutical formulations.
Methylpyrrolidone is mainly an irritant, but has also caused several cases of contact dermatitis in a small electrotechnical company.
Methylpyrrolidone is a member of the class of pyrrolidine-2-ones that is pyrrolidin-2-one in which the hydrogen attached to the nitrogen is replaced by a methyl group.

CAS: 872-50-4
MF: C5H9NO
MW: 99.13
EINECS: 212-828-1

Methylpyrrolidone has a role as a polar aprotic solvent.
Methylpyrrolidone is a N-alkylpyrrolidine, a lactam and a member of pyrrolidin-2-ones.
Methylpyrrolidone is a powerful, aprotic solvent with high solvency, and low volatility.
This colorless, high boiling, high flash point and low vapor pressure liquid carries a mild amine-like odor.
Methylpyrrolidone has high chemical and thermal stability and is completely miscible with water at all temperatures.
Methylpyrrolidone can serve as a co-solvent with water, alcohols, glycol ethers, ketones, and aromatic/chlorinated hydrocarbons.
Methylpyrrolidone is both recyclable by distillation and readily biodegradable.
Methylpyrrolidone is not found on the Hazardous Air Pollutants (HAPs) list of the 1990 Clean Air Act Amendments.

Methylpyrrolidone is an organic compound consisting of a 5-membered lactam.
Methylpyrrolidone is a colorless liquid, although impure samples can appear yellow.
Methylpyrrolidone is miscible with water and with most common organic solvents.
Methylpyrrolidone also belongs to the class of dipolar aprotic solvents such as dimethylformamide and dimethyl sulfoxide.
Methylpyrrolidone is used in the petrochemical, polymer and battery industries as a solvent, exploiting its nonvolatility and ability to dissolve diverse materials (including polyvinylidene difluoride, PVDF).

Methylpyrrolidone Chemical Properties
Melting point: -24 °C (lit.)
Boiling point: 202 °C (lit.) 81-82 °C/10 mmHg (lit.)
Density: 1.028 g/mL at 25 °C (lit.)
Vapor density: 3.4 (vs air)
Vapor pressure: 0.29 mm Hg ( 20 °C)
Refractive index: n20/D 1.479
Fp: 187 °F
Storage temp.: Store at +5°C to +30°C.
Solubility ethanol: miscible0.1ML/mL, clear, colorless (10%, v/v)
Form: Liquid
pka: -0.41±0.20(Predicted)
Color: ≤20(APHA)
PH: 8.5-10.0 (100g/l, H2O, 20℃)
Odor: Slight amine odor
PH Range: 7.7 - 8.0
Explosive limit: 1.3-9.5%(V)
Water Solubility: >=10 g/100 mL at 20 ºC
Sensitive: Hygroscopic
λmax: 283nm(MeOH)(lit.)
Merck: 14,6117
BRN: 106420
Stability:: Stable, but decomposes upon exposure to light. Combustible. Incompatible with strong oxidizing agents, strong acids, reducing agents, bases.
InChIKey: SECXISVLQFMRJM-UHFFFAOYSA-N
LogP: -0.46 at 25℃
CAS DataBase Reference: 872-50-4(CAS DataBase Reference)
NIST Chemistry Reference: Methylpyrrolidone(872-50-4)
EPA Substance Registry System: Methylpyrrolidone (872-50-4)

Methylpyrrolidone is a colourless or light yellow liquid with an amine odour.
Methylpyrrolidone can undergo a number of chemical reactions even though it is accepted as a stable solvent.
Methylpyrrolidone is resistant to hydrolysis under neutral conditions, but strong acid or base treatment results in ring opening to 4-methyl aminobutyric acid.
Methylpyrrolidone can be reduced to 1-methyl pyrrolidine with borohydride.
Treatment with chlorinating agents results in amide formation,an intermediate which can undergo further substitution, while treatment with amyl nitrate yields the nitrate.
Methylpyrrolidone can be added to the 3 position by treatment first with oxalic esters, then with appropriate aldehyes.

Uses
Methylpyrrolidone is a polar aprotic solvent that has the advantages of low toxicity, high boiling point, outstanding solvency, strong selectivity and good stability.
Methylpyrrolidone is widely used in purification of aromatic hydrocarbon extraction, acetylene, olefins, and diolefins.
Methylpyrrolidone is used in industrial cleaning, and it serves as a solvent for production of pesticides, engineering plastics, coatings, synthetic fibers, and integrated circuits.
Methylpyrrolidone can also be used as an industrial cleanser, dispersant, dye, lubricant and antifreeze.
Methylpyrrolidone is an excellent solvent, widely used in aromatics extraction, lubricating oil refining, acetylene enrichment, butadiene separation and synthesis gas desulfurization.

Methylpyrrolidone is used in gas desulfurization, lubricating oil refining, lubricating oil antifreeze, olefin extraction, and as a solvent for insoluble engineering plastics polymerization.
Methylpyrrolidone can be used in herbicide, to clean insulation materials, semiconductor industry precision instruments and circuit boards, to recycle PVC exhaust, as a detergent, dye supplement and dispersing agent.
Methylpyrrolidone is used in mediums for polymerization reactions such as engineering plastics and aramid fiber.
Methylpyrrolidone is used as a polyvinylidene fluoride solvent and electrode auxiliary material for lithium ion batteries.

Solvent for high-temperature resins; petrochemical processing, in the microelectronics fabrication industry, dyes and pigments, industrial and domestic cleaning compounds; agricultural and pharmaceutical formulations
Methylpyrrolidone, is useful for spectrophotometry, chromatography and ICP-MS detection.
Methylpyrrolidone is a polar solvent that is used in organic chemistry and polymer chemistry.
Large scale applications include the recovery and purification of acetylenes, olefins, and diolefins, gas purification, and aromatics extraction from feedstocks.
Methylpyrrolidone is a versatile industrial solvent.
Methylpyrrolidone is currently approved for use only in veterinary pharmaceuticals.
The determination of the disposition and metabolism of Methylpyrrolidone in the rat will contribute toward understanding the toxicology of this exogenous chemical which man may likely be exposed to in increasing amounts.

Methylpyrrolidone is used to recover certain hydrocarbons generated in the processing of petrochemicals, such as the recovery of 1,3-butadiene and acetylene.
Methylpyrrolidone is used to absorb hydrogen sulfide from sour gas and hydrodesulfurization facilities.
Methylpyrrolidone's good solvency properties have led to NMP's use to dissolve a wide range of polymers.
Specifically, Methylpyrrolidone is used as a solvent for surface treatment of textiles, resins, and metal coated plastics or as a paint stripper.
Methylpyrrolidone is also used as a solvent in the commercial preparation of polyphenylene sulfide.
In the pharmaceutical industry, Methylpyrrolidone is used in the formulation for drugs by both oral and transdermal delivery routes.
Methylpyrrolidone is also used heavily in lithium ion battery fabrication, as a solvent for electrode preparation, because NMP has a unique ability to dissolve polyvinylidene fluoride binder.
Due to Methylpyrrolidone's toxicity and high boiling point, there is much effort to replace it in battery manufacturing with other solvent(s), like water.

Industrial uses
1) Methylpyrrolidone is used as a general dipolar aprotic solvent, stable and unreactive;
2) for extraction of aromatic hydrocarbons from lubricating oils;
3) for carbon dioxide removal in ammonia generators;
4) as a solvent for polymerization reactions and polymers;
5) as a paint stripper;
6) for pesticide formulations.
Other non-industrial uses of Methylpyrrolidone are based on its properties as a dissociating solvent suitable for electrochemical and physical chemical studies.
Pharmaceutical applications make use of the properties of Methylpyrrolidone as a penetration enhancer for a more rapid transfer of substances through the skin.
Methylpyrrolidone has been approved as a solvent for slimicide application to food packaging materials.

Production Methods
Methylpyrrolidone is manufactured by the reaction of buytrolactone with methylamine.
Other processes include preparation by hydrogenation of solutions of maleic or succinic acids with methylamine.
Manufacturers of this chemical include Lachat Chemical, Inc, Mequon, Wisconsin and GAF Corporation, Covert City, California.

Health hazards
Methylpyrrolidone is an agent that causes the production of physical defects in the developing embryo.
Methylpyrrolidone also is a reproductive toxin, a chemical that is toxic to the reproductive system, including defects in the progeny and injury to male or female reproductive function. Reproductive toxicity includes developmental effects.
Methylpyrrolidone can be absorbed into the body by inhalation, through the skin and by ingestion.
When people are exposed to Methylpyrrolidone, rapid, irregular respiration, shortness of breath, decreased pain reflex, and slight bloody nasal secretion are possible.
Inhalation can result in headaches and exposure on skin can result in redness and pain.
When ingested Methylpyrrolidone will cause a burning sensation in the throat and chest.
Methylpyrrolidone also can cause an acute solvent syndrome.

Reactivity Profile
This amine is a very mild chemical base.
Methylpyrrolidone does tend to neutralize acids to form salts plus water.
The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base.
Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides.
Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Severe skin and eye irritant.
Explosive lim-its 2.2–12.2%.
Inhalation of hot vapors can irritate nose and throat.
Ingestion causes irritation of mouth and stomach.
Contact with eyes causes irritation.
Repeated and prolonged skin contact produces a mild, transient irritation.

Contact allergens
Methylpyrrolidone is an aprotic solvent with a wide range of applications: petrochemical processing, surface coating, dyes and pigments, industrial and domestic cleaning compounds, and agricultural and pharmaceutical formulations.
Methylpyrrolidone is mainly an irritant, but it can cause severe contact dermatitis due to prolonged contact.

Preparation
Methylpyrrolidone is produced industrially by a typical ester-to-amide conversion, by treating butyrolactone with methylamine.
Alternative routes include the partial hydrogenation of N-methylsuccinimide and the reaction of acrylonitrile with methylamine followed by hydrolysis.
About 200,000 to 250,000 tons are produced annually.

Synonyms
1-METHYL-2-PYRROLIDINONE
872-50-4
N-Methylpyrrolidone
N-Methyl-2-pyrrolidone
1-methylpyrrolidin-2-one
Methylpyrrolidone
1-Methyl-2-pyrrolidone
N-Methyl-2-pyrrolidinone
M-Pyrol
1-Methylpyrrolidinone
Methyl pyrrolidone
1-Methylpyrrolidone
N-Methylpyrrolidinone
n-methyl-pyrrolidone
2-Pyrrolidinone, 1-methyl-
1-Methyl-5-pyrrolidinone
1-Methylazacyclopentan-2-one
N-methylpyrrolidin-2-one
NMP
N-Methyl-gamma-butyrolactam
N-methyl pyrrolidone
1-methylpyrrolidine-2-one
N-methyl pyrrolidinone
Methyl-2-pyrrolidinone
1-methyl-2-pyrrolidon
Methylpyrrolidinone
2-Pyrrolidinone, methyl-
2687-44-7
Methylpyrrolidone [NF]
N-Methylpyrrolid-2-one
N-Methyl-alpha-pyrrolidone
NSC 4594
Agsolex 1
N-Methyl-alpha-pyrrolidinone
CCRIS 1633
51013-18-4
DTXSID6020856
Methylpyrrolidone, N-
HSDB 5022
Pyrrolidinone, methyl-
NSC-4594
EINECS 212-828-1
UNII-JR9CE63FPM
MFCD00003193
JR9CE63FPM
1-methyl-pyrrolidin-2-one
Norleucine, 5-oxo-, DL-
N-Methyl-.alpha.-pyrrolidone
1-Methyl-2-pyrrolidinone-d9
CHEMBL12543
N-Methyl-.gamma.-butyrolactam
AI3-23116
CHEBI:7307
N-Methyl-.alpha.-pyrrolidinone
1-Methyl-2-pyrrolidinone, anhydrous
1-Methyl-2-pyrrolidinone, HPLC Grade
EC 212-828-1
N 0131
30207-69-3
DTXCID60856
pharmasolve
N-Methylpyrrolidon
CAS-872-50-4
N-methyl-pyrrolidinone
N-Methylpyrrolidone; 1-Methylpyrrolidin-2-one
N-Methyl-2-pyrrolidon
1-methyl-2-pyrolidone
N-methyl-pyrrolidin-2-one
1-Methyl-2-pyrrolidinone, puriss. p.a., >=99.0% (GC)
Micropure ultra
N-methylpyrolidone
N-methypyrrolidone
Max-1 peptide
Pyrol M
N-methylpirrolidone
1methylpyrrolidinone
n-methyl pyrrolidon
N-methy pyrrolidone
N-methyl-pyrolidone
N-methyl-pyrrolidon
N-methylpyrolidinone
1-methylpyrolidinone
Microposit 2001
n-methylpyrollidinone
N-Methylpyrrolidione
N-methlypyrrolidinone
N-methyl pirrolidone
N-methyl pyrollidone
N-methyl-pyrollidone
N-methylpyrrolidone-
NMP,SP Grade
1-methyl pyrrolidone
1-methyl-pyrrolidone
methyl-2-pyrrolidone
N-methy pyrrolidinone
N-methyl pyrolidinone
N-methyl-pyrolidinone
N-methyl- pyrrolidone
N-methylpyrro-lidinone
N-methylpyrroli-dinone
N-methylpyrrolidin-one
1-methyl-2pyrrolidone
1-methyl2-pyrrolidone
1methyl-2-pyrrolidone
N-Metyl-2-pyrrolidon
1-methyl pyrrolidinone
1-methyl-pyrrolidinone
methylpyrrolidin-2-one
N-methy-2-pyrrolidone
N-methyl 2-pyrolidone
N-methyl-2-pyrolidone
1-Metil-2-pirrolidona
3p1d
N-methyl 2-pyrrolidone
N-methyl-2-pyrollidone
MPY (CHRIS Code)
1-methyl-2-pirrolidone
1-methyl-2-pyroldinone
1-methylpyrrolid-2-one
1methyl-2-pyrrolidinone
n-methylpyrrolidine-2one
N-methyl-2-pyrolidinone
N-methyl-2-pyrrolidinon
N-methylpyrolidin-2-one
1-methy-2-pyrrolidinone
1-methyl-2-pyrolidinone
N-methyl 2-pyrrolidinone
N-methyl-2-pyrollidinone
N-methyl-pyrrolid-2-one
N-methylpyrollidin-2-one
1 -methyl-2-pyrrolidone
1-methyl 2-pyrrolidinone
1-methyl-2-pyrollidinone
1-methyl-pyrrolin-2-one
N-Methylpyrrolidone-(2)
1-Methyl-pyrrolidin-2one
N-methylpyrrolidine-2-one
WLN: T5NVTJ A
N-methyl -2-pyrrolidinone
1 -methyl-2-pyrrolidinone
1-methyl -2-pyrrolidinone
1-methyl-2- pyrrolidinone
2-Pyrrolidone, 1-methyl-
1-methyl-pyrrolidine-2-one
2-pirrolidinona, 1-metil-
1-N-methyl-2-pyrrolidinone
N-methyl-pyrrolidin -2-one
1-Methylazacyclopentane-2-one
GTPL9520
METHYL PYRROLIDONE [II]
1-Methyl-2- pyrrolidin-2-one
N-Methyl-2-pyrrolidon (Dampf)
1-METHYLPYRROLIDONE [MI]
METHYL PYRROLIDONE [INCI]
NSC4594
METHYLPYRROLIDONE [USP-RS]
HY-Y1275
N-METHYLPYRROLIDONE [MART.]
Tox21_202350
Tox21_300097
1-Methyl-2-pyrrolidinone, 99.5%
BDBM50353587
N-Methyl pyrrolidon (Peptide Grade)
N-METHYLPYRROLIDONE [USP-RS]
s6282
STL183295
N-Methyl-2-pyrrolidinone ACS reagent
AKOS000120930
1-Methyl-2-pyrrolidinone, BioSolv(R)
DB12521

Chemical Characterization Tetraethylene glycol monomethyl ether Homologous mixture, n = 3–6 Main components are: Methyl tetraglycol (min. 60%) CAS-Nr.: 23783-42-8 Methyl pentaglycol CAS-Nr.: 23778-52-1 Registrations: EINECS (Europe), TSCA (USA), AICS (Australian),DSL (Canada), ECL (Korea), PICCS (Philippines), ENCS (Japan) Product Description Methyl tetraglycol is a clear yellowish, slightly hygroscopic and slightly mobile liquid with an extremely faint odour. It is miscible in any ratio with water and the usual organic solvents. Methyl tetraglycol exerts to the typical alcohol reactions. Methyl tetraglycol is used as a hydraulic fluid component e.g. in brake fluids. Because of its high dissolving power methyl tetraglycol is used in water-borne and solvent-borne coating formulations and as dispersing agent. Furthermore, methyl tetraglycol finds many applications in biochemistry and medicine, e.g. in herbicide formulations, X-ray contrast media and medicinal drugs. Also, the esterification with peptides influences the hydrophilic properties as well as the immunochemical resistance. In the electronic industry methyl tetraglycol is used in soldering agents and as regenerations fluid for LCD-cells. Storage advices Glycol ethers and their derivatives tend to form peroxides in the presence of air or oxygen. Due to the hygroscopicity of methyl tetraglycol correct storage in order to prevent absorption of water has to be ensured. It is recommended to reduce moisture pickup by nitrogen blanketing of storage tanks. Drying agents (silica gel) should be used if the tank is able to breath. Storage tanks should be made from stainless steel. Alumina and other light metals are not suitable due to alcoholate formation with methyl tetraglycol. Technical data Methyl tetraglycol molar mass g/mol ca. 208 Methyl tetraglycol boiling range/1013 hPa °C 280–350 Methyl tetraglycol solidification point (DIN 51583) °C -39 Methyl tetraglycol flash point (DIN 51758) °C 161 Methyl tetraglycol ignition temperature (DIN 51794) °C 325 Methyl tetraglycol vapour pressure/20 °C mbar <0,1 Methyl tetraglycol density/20 °C (DIN 51757) g/cm³ ca. 1,06 Methyl tetraglycol kinematic viscosity/20 °C (DIN 51562) mm²/s 11,5-12,5 Methyl tetraglycol miscibility with water/25 °C 100% miscible Methyl tetraglycol specific heat capacity kJ/kgK 2,4

Chemical Characterization Triethylene glycol monomethyl ether 2-(2-(2-Methoxyethoxy)-ethoxy)-ethanol CAS-No.: 112-35-6 Registrations: EINECS (Europe), TSCA (USA), AICS (Australian), DSL (Canada), ECL (Korea), PICCS (Philippines), ENCS (Japan), ASIA-PAC i.e. Product Description Methyl triglycol is a colorless, neutral, weakly hygroscopic and slightly mobile liquid with a mild pleasant odor. It is miscible in any ratio with water and the usual organic solvents e.g. acetone, diethyl ether, methanol. Methyl triglycol enters into the typical alcohol reactions. Methyltriglycol is used in brakefluid formulations und organic intermediates. Storage Advices Glycol ethers and their derivatives tend to form peroxides in the presence of air or oxygen. Due to the hygroscopicity Methyl triglycol storage to prevent absorption of water has to be ensured. It is recommended to reduce moisture pickup by nitrogen blanketing of storage tanks. Storage tanks should be made from stainless steel. Alumina and other light metals are not suitable due to alcoholate formation with methyl triglycol. Physical Data Methyl triglycol molar mass g/mol 164 Methyl triglycol boiling range/1013 hPa °C 240-280 Methyl triglycol freezing point (DIN 51583) °C -48 Methyl triglycol flash point(DIN 51755) °C ca. 125 Methyl triglycol ignition temperature (DIN 51794) °C 215 Methyl triglycol refractive number nD20 (DIN 51423, part 2) 1,4381 Methyl triglycol vapor pressure/20°C mbar 0,1 Methyl triglycol density/20°C (DIN 51757) g/cm³ ca. 1,05 Methyl triglycol kinematic viscosity/20°C (DIN 51562) mm²/s 7-7,5 Methyl triglycol miscibility with water 100% miscible

1,1'-sulfonylbis-methane; DMSO2;MSM; NSC 63345; CAS NO. 67-71-0

METHYLENE BIS MORPHOLINE; N,N-Dimorpholinomethane; Morpholine,4,4-methylenebis-; Bis(4-morpholinyl)methane; N,N'-Methylenebismorpholine; 4,4'-methanediyldimorpholine; 4,4-methylenebis-Morpholine; N,N-Methylene-bis-morpholine cas no: 5625-90-1

Trisodium dicarboxymethyl alaninate; * N,N-Bis(carboxymethyl)-DL-alanin trisodium salt; N-(1-Carboxyethyl)-iminodiacetic acid; α-Alanindiacetic acid; α-ADA; MGDA-Na3; Trilon M; carboxylatoethyl)iminodiacetate, methylglycinediacetic acid trisodium salt (MGDA-Na3) or trisodium α-DL-alanine diacetate (α-ADA), cas no: 164462-16-2

METHYLENE CHLORIDE; Dichloromethane; Freon 30; Methylene dichloride; Chlorure De Methylene (French); Chlorocarbon; Methylene Bichloride; Metylenu Chlorek (Polish); cas no: 75-09-2

silane, triethoxymethyl-; triethoxy(methyl)silane; triethoxy(methyl)silane cas no : 2031-67-6

SYNONYMS 1-Amino-3-methoxypropane; 3-methoxy-1-Propanamine;3-Methoxy-1-aminopropane; 3-Methoxypropane-1-amine; 3-甲氧基丙胺; CAS NO:5332-73-0

Dipropylene glycol methyl ether; 2-(2-methoxypropoxy)propan-1-ol ; Glycol Ether DPM; dipropyleneglycol monomethyl ether cas no:13588-28-8

1-Methoxy-2-propanol; PGME; 1-Methoxypropan-2-ol; polypropylene glycol methyl ether; propylene glycol 1-methyl ether; PM; (+/-)-1-methoxy-2-propanol; 1-Methoxy-2-hydroxypropane; Methoxy Propanol; 2-Methoxy- 1 -Methyl Ethanol; cas no: 107-98-2

METYL PARABEN; Methyl 4-hydroxybenzoate, sodium salt; Sodium 4-(methoxycarbonyl)phenolate; Natrium-4-(methoxycarbonyl)phenolat; 4-(metoxicarbonil)fenolato de sodio; 4-(méthoxycarbonyl)phénolate de sodium; Methyl paraben sodium salt; Sodium methyl 4-hydroxybenzoate; methyl-4-oxide-benzoate, sodium salt; Methyl p-hydroxybenzoate, sodium salt; cas no: 5026-62-0

METOLAT P 872 is a blend of glycols with an inorganic carrier
METOLAT P 872 is recommended for the use in dry mixtures which are to be blended or diluted with water prior to application.
METOLAT P 872 reduces the shrinkage in cementitious systems.

METOLAT P 872 reduces the shrinkage in cementitious systems and acts as coalescent in powder paints.
METOLAT P 872 range of products from Munzing Chemie are powder based products with various functions including defoaming, anti-shrinkage and pigment dispersion/particle wetting.
These powder product is primarily targeted at dry blend applications in the construction industry for gypsum, mineral and cementitious compounds.

METOLAT P 872 is recommended for the use in dry mixtures which are to be blended or diluted with water prior to application. ,
METOLAT P 871 reduces the shrinkage in cementitious systems and acts as coalescent in powder paints.
Normal dosage of METOLAT P 872 ranges from 0.5% to 5.0% for anti-shrinkage properties.

The best concentration will vary depending on the system and should be tested.
METOLAT P 872 is recommended for use in dry mixes to be mixed or diluted with water prior to application.
METOLAT P 872 reduces shrinkage in cement based systems.

AMETOLAT P 872 a blend of glycols typically refers to a mixture of different glycol compounds.
METOLAT P 872 is a class of organic compounds that contain multiple hydroxyl (-OH) groups.
METOLAT P 872 is often used as antifreeze agents, particularly in heating and cooling systems, to lower the freezing point of water, thus preventing pipes and equipment from freezing in cold temperatures.

METOLAT P 872 is used in some heat transfer fluids to improve the efficiency of heat exchange systems.
METOLAT P 872 is commonly used in various products like cosmetics, food, and pharmaceuticals as a humectant to retain moisture and prevent drying.
METOLAT P 872 is used in deicing solutions for aircraft, roads, and sidewalks to melt ice and snow.

METOLAT P 872 can be utilized in various industrial processes for their unique properties, such as their ability to control temperature and prevent freezing.
This is one of the most common glycols and is known for its antifreeze properties.
METOLAT P 872's used in automotive cooling systems to prevent engine coolant from freezing and also as a heat transfer fluid in some industrial applications.

METOLAT P 872 is often used in applications where toxicity is a concern.
METOLAT P 872 is commonly used in food, pharmaceuticals, and cosmetic products, such as moisturizers, shampoos, and personal care items.
METOLAT P 872 is also used in some antifreeze formulations, especially in situations where contact with humans or animals is possible.

METOLAT P 872 is used as a solvent and in the production of resins, plastics, and other industrial products.
METOLAT P 872 is used primarily as a dehydrating agent in natural gas and other petrochemical processing applications to remove water from the gas.
METOLAT P 872 is commonly used in skincare and cosmetic products as a moisturizer and humectant.

METOLAT P 872 helps to retain moisture in the skin.
METOLAT P 872 is a family of glycols with various molecular weights and are used in a wide range of applications.
They are found in pharmaceuticals, cosmetics, and as thickeners in some food products.

They also have applications in lubricants and as binders in the pharmaceutical industry.
METOLAT P 872 is used in various applications, including as a solvent in industries like fragrance and cosmetics, as well as in the manufacturing of plasticizers and resins.

Appearance: powder
Colour: white
Ash: approx. 42 %
Consistency: powder
Apparent density: approx. 380 g/l
Solubility in water: active ingredients soluble in water

METOLAT P 872 normal dosage ranges from 0.1 to 0.2 % for coalescent activity and 0.5 to 5.0 % for anti-shrink properties.
The optimum concentration will vary depending on the system and should be tested.

Uses:
METOLAT P 872 is a type of polyether glycol used as a base fluid in various industrial and commercial products.
METOLAT P 872 has applications in hydraulic fluids, lubricants, and as an ingredient in some personal care and cosmetic products.
These are a group of solvents derived from glycols, often used in paints, coatings, and cleaning products.

While not a glycol in the traditional sense, METOLAT P 872 is a small organic acid derived from sugar cane and used in skincare products, such as chemical peels and exfoliating solutions.
METOLAT P 872, is used in the food industry as food additives or preservatives.
They are generally recognized as safe (GRAS) when used within specified limits.

METOLAT P 872 may be used in the pharmaceutical industry as excipients or carriers in drug formulations.
They can improve the solubility and stability of certain drugs.
Various glycols find applications in chemical processing and synthesis as reaction intermediates or solvents.

They can be used to control reaction conditions and aid in product separation.
METOLAT P 872 is used in agriculture to help retain moisture in soil or to condition soil.
They can also be used in animal feed to maintain moisture content.

In addition to their use in natural gas processing, METOLAT P 872 is used as drying agents in air conditioning and refrigeration systems to remove moisture.
METOLAT P 872is sometimes used to create artificial smoke or fog in theatrical productions and special effects.
METOLAT P 872 is commonly used in automotive and industrial cooling systems to prevent overheating by raising the boiling point of the coolant and lowering the freezing point.

METOLAT P 872 and triethylene glycol (TEG), are used in natural gas processing to remove water and other impurities from natural gas streams.
METOLAT P 872s can be used as reaction solvents in various chemical processes, facilitating the mixing of reactants and controlling reaction conditions.
METOLAT P 872 is used in the production of plastics, resins, and polyurethanes. They can improve the flexibility and durability of these materials.

METOLAT P 872 is used in the textile industry as a component in dyeing processes, helping to disperse dyes evenly.
METOLAT P 872 can be used in printing inks to regulate the viscosity and improve ink spreading and drying properties.
METOLAT P 872 can be used as solvents and fixatives in the formulation of perfumes and fragrances.

METOLAT P 872 is used in cosmetics and personal care products as emollients, humectants, and solvents.
METOLAT P 872, is used as food additives, preservatives, and sweeteners in the food and beverage industry.
METOLAT P 872 can be used in pharmaceutical formulations as solvents, carriers, and stabilizers for drug delivery systems.

METOLAT P 872 can be used as solvents and standards in various analytical techniques, such as gas chromatography and liquid chromatography.
METOLAT P 872 is sometimes used as cleaning agents for various surfaces, such as glass and metals, due to their solvency properties.

Storage/Handling:
METOLAT P 871 is slightly hygroscopic.
The organic component slowly evaporates at higher temperatures.

METOLAT P 871 should be stored dry between 15 and 25 °C.
The minimum shelf life in closed containers is 15 months from the date of manufacture.

Safety Profile:
METOLAT P 872 is highly toxic to humans and animals when ingested.
Even small amounts can be lethal.
METOLAT P 872, on the other hand, is generally recognized as safe (GRAS) when used in food and cosmetic products and is much less toxic.

METOLAT P 872 is harmful to the environment and aquatic life.
METOLAT P 872s themselves are not highly flammable, some glycol-based products or mixtures may be flammable, depending on their composition.

Synonyms:
Glycol Mixture
Glycol Combination
Glycol Blend
Glycol Cocktail
Glycol Solution
Glycol Formulation
Glycol Compound

SYNONYMS D,L-methylglycinediacetic acid trisodium salt;;Trisodium 2-Methylnitrilotriacetate Hydrate;;methylglycine-N,N-diacetic acid trisodium salt;;TRISODIUM 2-METHYLNITRILOTRIACETATE;;methylglycinediacetic acid trisodium salt;;Methyl Glycine Diacetic Acid Trisodium Salt Hydrate;;N,N-Bis(carboxylatomethyl)alanine Trisodium Salt Hydrate;;N,N-BIS(CARBOXYLATOMETHYL)ALANINE TRISODIUM SALT; CAS NO:164462-16-2

MICROCRYSTALLINE CELLULOSE; Cellulose; Cellulose powder, Cotton linters; CAS Number 9004-34-6

Micaceous Iron Oxide is a natural mineral pigment with a distinctive flaky structure.
Micaceous Iron Oxide exhibits a shimmering appearance reminiscent of mica, hence the name.
Micaceous Iron Oxide is composed of iron oxide, specifically hematite.
Micaceous Iron Oxide is known for its excellent protective and anticorrosive properties.

CAS Number: 1317-61-9
EC Number: 215-277-5



APPLICATIONS


Micaceous Iron Oxide is widely used as a pigment in protective coatings for its corrosion-resistant properties.
Micaceous Iron Oxide is commonly employed in automotive coatings to provide rust and corrosion protection to vehicles.

Micaceous Iron Oxide is used in marine coatings to safeguard ships, boats, and offshore structures from the corrosive effects of saltwater.
Micaceous Iron Oxide finds application in heavy machinery and equipment coatings to enhance their durability and extend their lifespan.
Micaceous Iron Oxide is utilized in structural steel coatings to protect bridges, buildings, and infrastructure from corrosion.
Micaceous Iron Oxide is applied to oil, gas, and water pipelines to prevent corrosion and maintain their integrity.

Micaceous Iron Oxide finds application in storage tank coatings for chemicals, petroleum products, and other substances, ensuring corrosion resistance.
Micaceous Iron Oxide is employed in metal fabrication and coating processes for various metal products and components.
Micaceous Iron Oxide is used in protective coatings for bridges, railways, and other infrastructure to ensure long-term corrosion protection.
Micaceous Iron Oxide is utilized in offshore drilling rigs, platforms, and pipelines in the oil and gas industry to resist corrosion in harsh environments.

Micaceous Iron Oxide coatings are applied to power plant structures and equipment to protect against corrosion caused by high temperatures and harsh operating conditions.
Micaceous Iron Oxide finds application in chemical processing facilities to provide corrosion protection for equipment and structures.
Micaceous Iron Oxide is used in coatings for water treatment facilities and wastewater treatment plants to resist corrosion from chemicals and moisture.
Micaceous Iron Oxide is employed in the fabrication and coating of metal furniture, appliances, and decorative items to enhance durability and aesthetics.
Micaceous Iron Oxide is used in the protective coating of metal roofing to provide both visual appeal and corrosion resistance.

Micaceous Iron Oxide finds application in the coating of tanks and containers used for storage and transportation of various substances.
Micaceous Iron Oxide is utilized in the automotive industry for underbody coatings and chassis protection.
Micaceous Iron Oxide is applied to railings, fences, and gates to provide corrosion resistance and maintain their appearance.
Micaceous Iron Oxide finds application in the protective coating of agricultural equipment, such as tractors and farm machinery.

Micaceous Iron Oxide coatings are used in the construction industry for metal structures, reinforcing bars, and precast concrete elements to prevent corrosion.
Micaceous Iron Oxide is employed in the protective coating of industrial equipment, such as pumps, valves, and turbines.
Micaceous Iron Oxide finds application in the coating of storage racks, shelves, and cabinets in warehouses and industrial facilities.
Micaceous Iron Oxide is used in the coating of HVAC (Heating, Ventilation, and Air Conditioning) systems and ductwork to prevent corrosion and maintain efficiency.

Micaceous Iron Oxide finds application in the coating of electrical enclosures and cabinets to protect against corrosion and ensure electrical safety.
Micaceous Iron Oxide is utilized in the protective coating of metal fences, gates, and railings in residential, commercial, and public spaces.

Micaceous Iron Oxide is used in the coating of water tanks and reservoirs to prevent corrosion and maintain water quality.
Micaceous Iron Oxide finds application in the protective coating of offshore wind turbine structures to resist corrosion in marine environments.

Micaceous Iron Oxide is employed in the coating of metal fences and barriers along highways and roadways for corrosion protection.
Micaceous Iron Oxide coatings are used in the aerospace industry for aircraft components and structures to provide corrosion resistance.
Micaceous Iron Oxide finds application in the protective coating of storage cabinets and lockers in laboratories and medical facilities.

Micaceous Iron Oxide is utilized in the coating of amusement park rides and attractions to protect against corrosion.
Micaceous Iron Oxide is employed in the protective coating of playground equipment and outdoor recreational structures for durability and safety.
Micaceous Iron Oxide coatings are used in the coating of metal furniture and fixtures in outdoor environments for corrosion protection.

Micaceous Iron Oxide finds application in the coating of metal bridges and walkways to provide both aesthetics and corrosion resistance.
Micaceous Iron Oxide is utilized in the protective coating of underground pipes and conduits to prevent corrosion and maintain functionality.
Micaceous Iron Oxide is applied to metal storage shelves and racks in warehouses and industrial facilities for corrosion resistance.

Micaceous Iron Oxide finds application in the coating of metal frames and supports for solar panels to ensure long-term durability.
Micaceous Iron Oxide is used in the protective coating of agricultural machinery and equipment for corrosion prevention.
Micaceous Iron Oxide is employed in the coating of metal playground equipment and structures in schools and parks for safety and durability.

Micaceous Iron Oxide coatings are used in the protective coating of railings and handrails in residential and commercial buildings.
Micaceous Iron Oxide finds application in the coating of metal tanks and containers used for the storage and transportation of chemicals.
Micaceous Iron Oxide is utilized in the coating of metal enclosures for electronic equipment and control panels to prevent corrosion.
Micaceous Iron Oxide is applied to metal fixtures and fittings in swimming pools and water treatment facilities for corosion resistance.

Micaceous Iron Oxide finds application in the protective coating of metal frames and supports for solar thermal systems.
Micaceous Iron Oxide is used in the coating of metal components in automotive exhaust systems for corrosion prevention.
Micaceous Iron Oxide is employed in the coating of metal frames and structures for billboards and outdoor advertising displays.
Micaceous Iron Oxide coatings are used in the protective coating of metal components in HVAC systems for corrosion resistance.

Micaceous Iron Oxide finds application in the coating of metal parts and equipment used in the food and beverage industry for corrosion prevention.
Micaceous Iron Oxide is utilized in the coating of metal gates and barriers at airports and transportation hubs for durability and security.
Micaceous Iron Oxide is applied to metal parts and components in industrial machinery and equipment for corrosion protection and longevity.


Here are some common applications of Micaceous Iron Oxide:

Corrosion Protection:
Micaceous Iron Oxide is extensively used as a pigment in protective coatings for metal surfaces, providing long-term corrosion protection.

Automotive Coatings:
Micaceous Iron Oxide is employed in automotive primers and coatings to protect vehicles from rust and corrosion.

Marine Coatings:
Micaceous Iron Oxide is used in marine paints and coatings to safeguard ships, offshore platforms, and other maritime structures from the corrosive effects of saltwater.

Industrial Machinery:
Micaceous Iron Oxide finds application in heavy machinery and equipment coatings to enhance their durability and resistance to corrosion.

Structural Steel:
Micaceous Iron Oxide is utilized as a protective coating for structural steel used in construction projects, bridges, and infrastructure, ensuring longevity and corrosion resistance.

Architectural Coatings:
Micaceous Iron Oxide is employed in architectural paints and coatings for buildings, providing both aesthetic appeal and corrosion protection.

Pipeline Coatings:
Micaceous Iron Oxide is used in pipeline coatings to prevent corrosion and ensure the integrity of oil, gas, and water pipelines.

Storage Tanks:
Micaceous Iron Oxide is applied to storage tanks, such as those used for chemicals or petroleum products, to protect against corrosion and maintain the integrity of the tanks.

Metal Fabrication:
Micaceous Iron Oxide is used in the fabrication and coating of metal products, including metal furniture, machinery, and metal structures.

Bridges and Infrastructure:
Micaceous Iron Oxide finds application in protective coatings for bridges, railways, and other infrastructure to prevent corrosion and extend their service life.

Oil and Gas Industry:
Micaceous Iron Oxide coatings are utilized in the oil and gas industry for equipment and structures exposed to harsh environments, such as offshore drilling rigs, platforms, and pipelines.

Power Plants:
Micaceous Iron Oxide is used in coatings for power plant structures and equipment to protect against corrosion caused by high temperatures and harsh operating conditions.

Chemical Processing Facilities:
Micaceous Iron Oxide coatings provide corrosion protection for equipment and structures in chemical processing plants.

Water and Wastewater Treatment:
Micaceous Iron Oxide finds application in coatings for water treatment facilities, wastewater treatment plants, and tanks to resist corrosion from chemicals and moisture.

Metal Roofing:
Micaceous Iron Oxide is sometimes used in coatings for metal roofing to provide both aesthetic appeal and corrosion resistance.



DESCRIPTION


Micaceous Iron Oxide (Micaceous Iron Oxide), also known as hematite or specular hematite, is a naturally occurring mineral pigment that belongs to the iron oxide group.
Its chemical formula is Fe2O3, indicating that it consists of two iron (Fe) atoms bonded to three oxygen (O) atoms.

Micaceous Iron Oxide has a unique flaky or micaceous structure, resembling the shimmering appearance of mica.
This characteristic gives it excellent protective and anticorrosive properties, making it a popular choice for various industrial applications.
Micaceous Iron Oxide is primarily used as a pigment and as a barrier coating in protective paints and primers.

The flaky structure of Micaceous Iron Oxide provides a barrier against moisture, gases, and chemicals, thereby protecting the substrate from corrosion.
Micaceous Iron Oxide also offers good UV resistance, high temperature stability, and excellent adhesion properties.
These attributes make Micaceous Iron Oxide suitable for applications such as automotive coatings, marine paints, heavy-duty machinery, structural steel, and other metal surfaces that require long-term protection against corrosion.

Micaceous Iron Oxide is often mixed with other pigments or binders to enhance its performance or to achieve specific color shades.
Micaceous Iron Oxide is available in different grades based on particle size distribution and purity, allowing manufacturers to select the most suitable grade for their specific requirements.

Micaceous Iron Oxide is a natural mineral pigment with a distinctive flaky structure.
Micaceous Iron Oxide exhibits a shimmering appearance reminiscent of mica, hence the name.
Micaceous Iron Oxide is composed of iron oxide, specifically hematite.
Micaceous Iron Oxide is known for its excellent protective and anticorrosive properties.

Micaceous Iron Oxide is widely used in industrial applications, particularly in protective coatings.
The flaky structure of Micaceous Iron Oxide acts as a barrier against moisture and chemicals.
Micaceous Iron Oxide provides long-lasting protection against corrosion on various surfaces.

Micaceous Iron Oxide offers good adhesion to metal substrates.
Micaceous Iron Oxide has exceptional durability, making it suitable for harsh environments.
Micaceous Iron Oxide is resistant to UV radiation, maintaining its color and integrity over time.
Micaceous Iron Oxide is commonly used in automotive coatings to protect against rust.

Micaceous Iron Oxide is utilized in marine paints to prevent corrosion on ships and other maritime structures.
Micaceous Iron Oxide finds applications in heavy machinery and equipment, extending their lifespan.
Micaceous Iron Oxide is also used in architectural coatings for long-term protection.

Micaceous Iron Oxide provides a decorative element to coatings, imparting a unique shimmer or metallic effect.
Micaceous Iron Oxide has high-temperature stability, making it suitable for industrial applications.
Micaceous Iron Oxide enhances the fire resistance of coatings.

Micaceous Iron Oxide is compatible with various binders and can be easily incorporated into formulations.
Micaceous Iron Oxide is available in different particle size distributions to suit specific coating requirements.
Micaceous Iron Oxide can be blended with other pigments to achieve desired color shades.
Micaceous Iron Oxide offers excellent weather resistance, maintaining its properties even in harsh climatic conditions.
Micaceous Iron Oxide has low solubility and does not easily leach into the environment.

Micaceous Iron Oxide is non-toxic and poses minimal health risks.
Micaceous Iron Oxide is an environmentally friendly option for corrosion protection.
The versatility and reliability of Micaceous Iron Oxide make it a popular choice in various industries.



PROPERTIES


Chemical Formula: Fe2O3
Appearance: Flaky or micaceous structure, resembling mica
Color: Typically dark gray or black, with metallic luster
Density: 4.8 - 5.2 g/cm3
Melting Point: Approximately 1,565°C (2,849°F)
Solubility: Insoluble in water and organic solvents
Particle Size Distribution: Available in different grades with varying particle sizes
Purity: Varies based on grade and manufacturer specifications
Corrosion Resistance: Provides excellent barrier protection against corrosion
Adhesion: Exhibits good adhesion to metal substrates
UV Resistance: Offers high resistance to ultraviolet (UV) radiation
Temperature Stability: Shows stability at high temperatures
Moisture Barrier: Acts as a barrier against moisture and water vapor
Chemical Resistance: Resistant to many chemicals and environmental factors
Aesthetic Appeal: Imparts a unique metallic or shimmering effect to coatings
Longevity: Provides long-lasting corrosion protection
Weather Resistance: Maintains its properties under various weather conditions



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air.
If breathing difficulties persist, seek immediate medical attention.
Administer artificial respiration if necessary and if trained to do so.
Provide oxygen support if available.


Skin Contact:

Remove contaminated clothing and rinse the affected area with plenty of water.
Gently wash the skin with mild soap and water.
If irritation or redness occurs, seek medical advice.
In case of chemical burns, apply appropriate first aid measures and seek immediate medical attention.


Eye Contact:

Flush the eyes gently with clean water for at least 15 minutes, holding the eyelids open.
Remove contact lenses if present and easy to do so.
Seek immediate medical attention for further evaluation and treatment.


Ingestion:

Rinse the mouth with water but do not induce vomiting.
Seek medical attention immediately.
Provide the medical personnel with detailed information about the substance.


General First Aid Measures:

Remove the affected person from the exposure area to a well-ventilated space.
Ensure rest and comfort for the affected person.
If necessary, seek medical attention promptly.
Provide the medical personnel with relevant information about the substance for appropriate treatment.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear suitable protective clothing, including gloves, safety goggles, and a dust mask or respirator, to minimize exposure.
Select PPE based on the specific handling procedures and product characteristics, following manufacturer's recommendations.

Ventilation:
Ensure adequate ventilation in the working area to minimize the potential for airborne dust or fumes.
Use local exhaust ventilation or dust collection systems when handling the material to control dust dispersion.

Avoiding Dust Generation:
Handle the material in a manner that minimizes the generation of dust.
Use appropriate handling equipment, such as closed systems or containers, to prevent spills and dust release.

Avoiding Contact:
Avoid skin and eye contact with Micaceous Iron Oxide.
In case of contact, promptly follow the recommended first aid measures mentioned previously.

Hygiene Practices:
Wash hands thoroughly with soap and water after handling the material.
Do not eat, drink, or smoke in areas where the material is being handled.
Maintain good personal hygiene practices to minimize any potential exposure.


Storage:

Storage Area:
Store Micaceous Iron Oxide in a cool, dry, well-ventilated area away from direct sunlight and incompatible substances.
Follow local regulations and guidelines for proper storage conditions.

Temperature and Humidity:
Avoid exposing the material to extreme temperatures and high humidity, as it may affect its properties and performance.

Containers:
Store the material in tightly sealed containers specifically designed for the storage of dry powders.
Ensure containers are labeled properly with relevant information, including the product name, hazards, and handling precautions.

Segregation:
Store Micaceous Iron Oxide away from incompatible materials to prevent any potential reactions or contamination.

Spill and Leak Measures:
Implement proper spill control measures, such as using appropriate absorbent materials, to contain and clean up any spills promptly.
Follow established procedures and regulations for the disposal of contaminated materials.

Fire Precautions:
Micaceous Iron Oxide is not flammable, but in case of a fire involving the surrounding area, use standard firefighting procedures and equipment.



SYNONYMS


Micaceous Iron Oxide
Micaceous Hematite
Micaceous Ferric Oxide
Micaceous Red Iron Oxide
Micaceous Iron Ore
Specular Hematite
Specularite
Natural Lamellar Iron Oxide
Natural Micaceous Iron Oxide
Natural Micaceous Hematite
Lamellar Iron Oxide
Iron(III) Oxide
Hematite
Red Iron Oxide
Natural Red Oxide
Natural Iron Oxide
Ferric Oxide
Fe2O3
Iron Trioxide
Red Ochre
Bloodstone
English Red
Indian Red
Rouge
Raddle
Rust
Goethite
Martite
Iron Rust
Colcothar
Ferric Red
Ferruginous Earth
Terra Rossa
Haematite
Iron Sesquioxide
Micaceous Red Ochre
Micaceous Red Iron Ore
Micaceous Hematite Ore
Lamellar Hematite
Glossy Hematite
Shiny Iron Oxide
Metallic Iron Oxide
Flake Iron Oxide
Micaceous Iron Rust
Shimmering Iron Oxide
Sparkling Iron Oxide
Lustrous Iron Oxide
Glittering Iron Oxide
Glistening Iron Oxide
Iridescent Iron Oxide
Gleaming Iron Oxide
Shining Hematite
Reflective Iron Oxide
Silvery Iron Oxide
Glimmering Iron Oxide
Shimmery Hematite
Glinting Iron Oxide
Brilliant Iron Oxide
Burnt Sienna
Burnt Umber

MIPA-COCOYL SARCOSINATE, Nom INCI : MIPA-COCOYL SARCOSINATE. Ses fonctions (INCI). Agent nettoyant : Aide à garder une surface propre Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation

Microcrystalline Cellulose is a term for refined wood pulp
Microcrystalline Cellulose is used as a texturizer
Microcrystalline Cellulose can be used as an anti-caking agent


CAS NUMBER: 9004-34-6

EC NUMBER: 232-674-9

MOLECULAR FORMULA: C12H22O11

MOLECULAR WEIGHT: 342.30 g/mol

IUPAC NAME: (6S)-2-(hydroxymethyl)-6-[(3S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol


Microcrystalline Cellulose is used as a fat substitute
Microcrystalline Cellulose also used as an emulsifier and an extender

Microcrystalline Cellulose is used as a bulking agent in food production.
The most common form is used in vitamin supplements or tablets.
Microcrystalline Cellulose is also used in plaque assays for counting viruses, as an alternative to carboxymethylcellulose.

Structure
A naturally occurring polymer, Microcrystalline Cellulose is composed of glucose units connected by a 1-4 beta glycosidic bond.
These linear cellulose chains are bundled together as microfibril spiralled together in plant cell walls.

Each microfibril exhibits a high degree of three-dimensional internal bonding resulting in a crystalline structure that is insoluble in water and resistant to reagents.
There are, however, relatively weak segments of the microfibril with weaker internal bonding.
These are called amorphous regions; some argue that they are more accurately called dislocations, because of the single-phase structure of microfibrils.
The crystalline region is isolated to produce microcrystalline cellulose.

USES:
Microcrystalline Cellulose is as a thickener, stabilizer or emulsifier, microcrystalline cellulose was granted the E number E460(i) with basic cellulose given the number E460.
Microcrystalline Cellulose has use in cosmetics as an abrasive, absorbent, anti-caking agent, aqueous viscosity increasing agent, binder, bulking agent, emulsion stabilizer, slip modifier, and texturizer, which can be found in various hair and skin care products as well as makeup.

The Microcrystalline Cellulose is a valuable additive in pharmaceutical, food, cosmetic and other industries.
Different properties of Microcrystalline Cellulose are measured to qualify its suitability to such utilization, namely particle size, density, compressibility index, angle of repose, powder porosity, hydration swelling capacity, moisture sorption capacity, moisture content, crystallinity index, crystallite size, and mechanical properties such as hardness and tensile strength.

Synthesis of It:
Microcrystalline Cellulose is pure partially depolymerized cellulose synthesized from α-cellulose precursor.
Microcrystalline Cellulose can be synthesized by different processes such as reactive extrusion, enzyme mediated, mechanical grinding, ultrasonication, steam explosion and acid hydrolysis.
The later process can be done using mineral acids such as H2SO4, HCl and HBr as well as ionic liquids.
The role of these reagents is to destroy the amorphous regions leaving the crystalline domains.

Microcrystalline Cellulose is refined wood pulp.
Microcrystalline Cellulose is a white, free-flowing powder.
Chemically, Microcrystalline Cellulose is an inert substance, is not degraded during digestion and has no appreciable absorption.
In large quantities Microcrystalline Cellulose provides dietary bulk and may lead to a laxative effect.

Microcrystalline Cellulose is a commonly used excipient in the pharmaceutical industry.
Microcrystalline Cellulose has excellent compressibility properties and is used in solid dose forms, such as tablets.
Tablets can be formed that are hard, but dissolve quickly.
Microcrystalline Cellulose is the same as cellulose, except that it meets USP standards.

Microcrystalline Cellulose is also found in many processed food products, and may be used as an anti-caking agent, stabilizer, texture modifier, or suspending agent among other uses.
Microcrystalline Cellulose is the most commonly used spheronizing aid in a formulation undergoing extrusion spheronization.

Microcrystalline Cellulose plays a variety of roles in cosmetic formulations including as an abrasive, absorbent, emulsion stabiliser, slip modifier and viscosity-increasing agent.
Microcrystalline Cellulose is defined as the isolated, colloidal crystalline portion of cellulose fibers, which can be plant derived or created synthetically.

Microcrystalline Cellulose is an important ingredient in pharmaceutical, food, cosmetic and other industries.
Microcrystalline Cellulose is made from high-grade, purified wood cellulose.

Hydrolysis is used to remove cellulose until the microcrystalline form remains.
With its amorphous cellulose portions removed, it becomes an inert, white, free-flowing powder.
Microcrystalline Cellulose can be processed in a number of ways, through reactive extrusion, steam explosion, and acid hydrolysis.

Pharmaceutical Areas:
All cellulose derivatives have their own pharmaceutical properties, but Microcrystalline Cellulose is the most versatile agent in the industry.
Microcrystalline Cellulose can be used to make tablets more compressible and to bind both wet and dry manufacturing processes.
Microcrystalline Cellulose's thickening powers and viscosity make it an important cellulose in liquid dosage forms.
Grades with a larger particle size and higher crystallization work well with colloidal silicon dioxide to produce silicide and second-generation grades.
Microcrystalline Cellulose is an excellent bioadhesive, and is used in bioadhesive drug delivery systems.

Interesting Facts about Microcrystalline Cellulose:
Microcrystalline Cellulose is used as an anti-caking agent in the processed food niche, but it's also a popular texturiser for cosmetics.
Microcrystalline Cellulose's a refined wood pulp with a unique hydroswelling talent.
Microcrystalline Cellulose can be synthesized in several ways through reactive extrusion, ultrasonication, and steam explosion.
More recently, Microcrystalline Cellulose's cleared a place for itself in the 3D printing niche.
Some have called Microcrystalline Cellulose an "inexhaustible treasure" for the pharmaceutical industry because it lends itself to a huge number of processes.
At its most straightforward, Microcrystalline Cellulose's used to achieve oral dosage forms in direct compression.
Microcrystalline Cellulose's remarkable flow makes it much easier to ensure a consistent tablet weight.

Benefits of Microcrystalline Cellulose:
In terms of particle size Microcrystalline Cellulose can be engineered to different um sizes.
Due to its microcrystalline structure it offers a naturally large surface area with plenty of porosity and moisture retention powers.
Microcrystalline Cellulose's often referred to as the best extrusion aid on the market for its excellent binding properties and cohesiveness.

If water movement is well-controlled, phase separation is completely avoidable.
Microcrystalline Cellulose can create a dense, smooth surface that's extremely nonfriable.
Microcrystalline Cellulose deforms under compression but forms powerful hydrogen bonds.


PHYSICAL PROPERTIES:

-Molecular Weight: 342.30 g/mol

-XLogP3-AA: -4.7

-Exact Mass: 342.11621151 g/mol

-Monoisotopic Mass: 342.11621151 g/mol

-Topological Polar Surface Area: 190Ų

-Physical Description: white, odourless powder

-Color: Colorless

-Form: Solid

-Odour: Odorless

-Boiling Point: Decomposes

-Melting Point: 500-518 °F

-Solubility: Insoluble in water, ethanol, ether and dilute mineral acids

-Density: 1.27-1.61

-Vapor Pressure: 0 mmHg


Microcrystalline Cellulose is an isolated, colloidal crystalline portion of cellulose fibers.
Microcrystalline Cellulose is a proven filler and stabilizer in food, cosmetics, capsules and tablets.

Microcrystalline Cellulose is obtained from plant fibre cellulose.
Microcrystalline Cellulose is the natural substance par excellence
Microcrystalline Cellulose can be found in the cell walls of all plants and is the most abundant organic compound.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 8

-Hydrogen Bond Acceptor Count: 11

-Rotatable Bond Count: 4

-Heavy Atom Count: 23

-Formal Charge: 0

-Complexity: 382

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 2

-Undefined Atom Stereocenter Count: 8

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes

-Chemical Classes: Biological Agents -> Polysaccharides


To obtain Microcrystalline Cellulose, cellulose is treated with mineral acids to produce a white, crystalline powder.
Microcrystalline Cellulose is chemically identical to the original cellulose.
Only the particle size (it is now "micro") and crystallinity (it is now powdery white) change – and this is also visible in the name: microcrystalline cellulose.

Microcrystalline Cellulose is non-digestible plant matter in sources like refined wood pulp and tough plant stalks
Microcrystalline Cellulose is a natural polymer.


ADVANTAGES:
*Flowability is improved

*Requires lower compression pressures

*Compactibility after wet granulation is maintained

*Compacts exhibit greater stiffness

*Higher lubrication efficiency


Microcrystalline Cellulose is a white, free-flowing powder.
These plants are harvested, cleaned, and ground to create a fine, white powder.
Microcrystalline Cellulose is called "microcrystalline" because its tiny crystals can only be viewed under a microscope.

Microcrystalline Cellulose is used as a texturizer
Microcrystalline Cellulose can be used as an anti-caking agent

Microcrystalline Cellulose is used as a fat substitute and an emulsifier
Microcrystalline Cellulose also used as an extender

Microcrystalline Cellulose is a bulking agent in food production.
The most common form is used in vitamin supplements or tablet.

Microcrystalline Cellulose is a white, free-flowing powder.
Chemically, Microcrystalline Cellulose is an inert substance, is not degraded during digestion and has no appreciable absorption.
In large quantities Microcrystalline Cellulose provides dietary bulk and may lead to a laxative effect.

Microcrystalline Cellulose is a commonly used excipient in the pharmaceutical industry.
Microcrystalline Cellulose has excellent compressibility properties and is used in solid dose forms, such as tablets.

Microcrystalline Cellulose is a refined wood pulp that is used for various applications.
Microcrystalline Cellulose is utilized as anti-caking agent

Microcrystalline Cellulose is an odorless, white powdery fibers.
Microcrystalline Cellulose's density is 1.5 g/cm3.

The biopolymer composing the cell wall of vegetable tissues.
Microcrystalline Cellulose is prepared by treating cotton with an organic solvent to de-wax it and removing pectic acids by extration with a solution of sodium hydroxide.

The principal fiber composing the cell wall of vegetable tissues (wood, cotton, flax, grass, etc.).
Microcrystalline Cellulose is insoluble in water.

Microcrystalline Cellulose is soluble with chemical degradation in sulfuric acid, and in concentrated solutions of zinc chloride.
Microcrystalline Cellulose is also soluble in aqueous solutions of cupric ammonium hydroxide (Cu(NH3)4(OH)2).

Microcrystalline Cellulose is a glycoside.
Microcrystalline Cellulose is a natural product found in Hyphaene thebaica and Aronia melanocarpa with data available.

Microcrystalline Cellulose is a gum that is the nonfibrous form of cellulose
Microcrystalline Cellulose is an alpha-cellulose.

Microcrystalline Cellulose is dispersible in water but not soluble, requiring considerable energy to disperse and hydrate.
In this form Microcrystalline Cellulose is used in dry applications such as tableting, capsules, and shredded cheese where it functions as a non-nutritive filler, binder, flow aid, and anticaking agent.

Microcrystalline Cellulose is a carbohydrate polymer made up of glucose units.
Microcrystalline Cellulose consists of fibrous particles and is used as a fiber source and bulking agent in low-calorie formulations.

Microcrystalline Cellulose is a thickener and an emulsifier.
Microcrystalline Cellulose is obtained from plants.

Microcrystalline Cellulose is used as an emulsifier in cosmetic creams.
Microcrystalline Cellulose is the chief constituent of plant fiber.


SYNONYMS:

cellulose
DEAE-CELLULOSE
9004-34-6
Cellulose, 2-(diethylamino)ethyl ether
(6S)-2-(hydroxymethyl)-6-[(3S)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Diethylaminoethyl cellulose
Cellulosepulver
DEAE-Sephacel(R)
UNII-85AMG1WQ9L
Diethylaminoethyl-Sephacel(R)
CHEBI:156274
CELLULOSE, DIETHYLAMINOETHYL
AKOS015895024
EN300-381040
(5S)-6-(hydroxymethyl)-5-{[(2S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxane-2,3,4-triol
(6S)-2-(HYDROXYMETHYL)-6-{[(3S)-4,5,6-TRIHYDROXY-2-(HYDROXYMETHYL)OXAN-3-YL]OXY}OXANE-3,4,5-TRIOL
Diethylaminoethyl-Sephacel(R)
AVICEL PH
AVICEL PH 101(R)
AVICEL PH 102
AVICEL PH 105(R)
AVICEL(R)
AVICEL(R)
AVICEL SF
AVIRIN

Microcrystalline cellulose is a refined wood pulp or plant fiber that is processed into a fine, white, odorless powder.
Microcrystalline cellulose is primarily composed of cellulose, which is a complex carbohydrate found in the cell walls of plants.
Microcrystalline cellulose is insoluble in water and other common organic solvents.

CAS Number: 9004-34-6



APPLICATIONS


Microcrystalline cellulose is widely used as a pharmaceutical excipient, providing excellent binding, disintegrating, and flow properties in tablet formulations.
Microcrystalline cellulose is employed in food products as a texturizer, stabilizer, and fat replacer, improving the texture and mouthfeel of various food items.

Microcrystalline cellulose is utilized in cosmetics and personal care products as a bulking agent, emulsion stabilizer, and viscosity enhancer.
Microcrystalline cellulose finds application in dietary supplements, acting as a filler and binder for encapsulation and tablet manufacturing.
Microcrystalline cellulose is used in the production of paper and paperboard, improving strength, porosity, and printability.
Microcrystalline cellulose is employed in the textile industry for sizing, providing improved yarn strength and weaving efficiency.

Microcrystalline cellulose is used in the production of ceramics and porcelain, enhancing moldability, green strength, and firing properties.
Microcrystalline cellulose is utilized in drilling muds for oil and gas exploration to control fluid viscosity and provide filtration control.

Microcrystalline cellulose is incorporated into rubber and plastic formulations to enhance mechanical properties and processability.
Microcrystalline cellulose is employed in paint and coating additives to improve stability, rheology, and texture.
Microcrystalline cellulose finds application in environmental remediation for adsorption and removal of contaminants in soil and groundwater.

Microcrystalline cellulose is used in foundry sands to enhance flowability, reduce casting defects, and improve surface finish in metal casting.
Microcrystalline cellulose is employed in rubber compounding to improve filler dispersion, processability, and performance of rubber products.
Microcrystalline cellulose is used as a binder and flow enhancer in animal feed formulations to improve pellet formation and handling.
Microcrystalline cellulose finds application in facial cleansers, body washes, and exfoliating scrubs as a gentle abrasive agent and texture enhancer.

Microcrystalline cellulose is used in the production of effervescent tablets to improve their disintegration and dissolution properties.
Microcrystalline cellulose is employed in the production of ceramic cores for investment casting to provide dimensional accuracy and stability.
Microcrystalline cellulose finds application in thermal insulation materials to enhance structural integrity and thermal performance.

Microcrystalline cellulose is used in the production of synthetic fibers, improving fiber strength and processability.
Microcrystalline cellulose can be applied as a soil amendment in agriculture to enhance water retention and nutrient availability for plant growth.
Microcrystalline cellulose is used in abrasive and polishing compounds for surface cleaning, smoothing, and polishing applications.
Microcrystalline cellulose finds application as a coating material or encapsulating agent for controlled release and protection of active ingredients.

Microcrystalline cellulose is utilized in water treatment processes for filtration and clarification to remove suspended particles and impurities.
Microcrystalline cellulose is incorporated into fire retardant formulations to improve flame resistance and safety in various applications.
Microcrystalline cellulose finds application in the production of oral disintegrating tablets, providing rapid disintegration and drug release.


Microcrystalline cellulose (MCC) has a wide range of applications across different industries.
Some of its common applications include:

Pharmaceutical Industry:
Microcrystalline cellulose is extensively used as an excipient in pharmaceutical formulations, particularly in tablet manufacturing.
Microcrystalline cellulose acts as a binder, diluent, disintegrant, and flow aid, providing improved tablet hardness, uniformity, and drug release.

Food and Beverage Industry:
Microcrystalline cellulose is used as a food additive, providing various functionalities such as thickening, stabilizing, and texture enhancement.
Microcrystalline cellulose is commonly found in baked goods, dairy products, sauces, dressings, and beverages.

Cosmetic and Personal Care Products:
Microcrystalline cellulose is utilized in cosmetics and personal care products as a bulking agent, texture modifier, and stabilizer.
Microcrystalline cellulose helps to improve product consistency, viscosity, and overall performance.

Dietary Supplements:
Microcrystalline cellulose is a popular ingredient in dietary supplements, providing benefits such as improved flow properties, uniformity, and controlled release of active ingredients.

Oral Care Products:
Microcrystalline cellulose is used in toothpaste and mouthwash formulations as a binder, thickener, and abrasive agent for effective cleaning and texture enhancement.

Paper and Pulp Industry:
Microcrystalline cellulose is employed as a binding agent, coating additive, and texture enhancer in the production of paper and paperboard.
Microcrystalline cellulose improves paper strength, printability, and smoothness.

Paints and Coatings:
Microcrystalline cellulose is used as a rheology modifier and thickener in water-based paints and coatings, improving their viscosity, stability, and application properties.

Building Materials:
Microcrystalline cellulose can be incorporated into cementitious materials, such as mortar and plaster, to enhance workability, cohesion, and crack resistance.

Filtration and Separation:
Microcrystalline cellulose is utilized as a filter aid in various industrial filtration processes, including pharmaceutical filtration, wastewater treatment, and beverage clarification.

Agrochemicals:
Microcrystalline cellulose is used as an inert carrier and dispersing agent in the formulation of pesticides, herbicides, and fertilizers, enhancing their effectiveness and handling characteristics.

Textile Industry:
Microcrystalline cellulose is employed as a binder in textile printing and dyeing processes, improving color fastness and fabric stability.

3D Printing:
Microcrystalline cellulose can be used as a filler and binder in 3D printing filaments, helping to enhance the structural integrity and dimensional stability of printed objects.

Energy Storage:
Microcrystalline cellulose has been explored as a component in electrodes for energy storage devices, such as supercapacitors and batteries, due to its high surface area and electrical conductivity.

Ceramic Industry:
Microcrystalline cellulose is utilized as a binder and pore-forming agent in ceramic manufacturing processes, improving green strength and controlling porosity.

Adhesives and Sealants:
Microcrystalline cellulose can be incorporated into adhesive and sealant formulations to improve cohesion, viscosity, and adhesion properties.

Texturized Foods:
Microcrystalline cellulose is used in the production of texturized or structured foods, providing desired textures and enhancing mouthfeel.

Pharmaceutical Excipient Compatibility Studies:
Microcrystalline cellulose is often used as a reference material in compatibility studies between drug substances and excipients to assess stability and interactions.

Biotechnology and Biomedical Applications:
Microcrystalline cellulose finds applications in biotechnology and biomedical research, such as cell culture support, drug delivery systems, and scaffold materials.

Carbonization and Activated Carbon Production:
Microcrystalline cellulose can be carbonized and converted into activated carbon for various applications, including adsorption, water purification, and gas separation.

Soil Stabilization:
Microcrystalline cellulose can be added to soil to improve its stability, erosion resistance, and water-holding capacity in landscaping and construction projects.

Ceramic and Porcelain Production:
Microcrystalline cellulose can be used as a binder and filler in the production of ceramic and porcelain products, helping to improve the workability of the clay mixture, enhance green strength, and control shrinkage during firing.

Oil and Gas Industry:
Microcrystalline cellulose is utilized in drilling mud formulations to control fluid viscosity, provide filtration control, and enhance wellbore stability during drilling operations.

Rubber and Plastics Industry:
Microcrystalline cellulose is incorporated into rubber and plastic formulations as a filler and reinforcing agent, improving mechanical properties, such as tensile strength, elasticity, and dimensional stability.

Paint and Coating Additives:
Microcrystalline cellulose can be used as a suspending agent, anti-settling agent, and rheology modifier in paints and coatings, contributing to improved stability, flow properties, and texture.

Textile Sizing:
Microcrystalline cellulose is employed as a sizing agent in textile manufacturing processes, particularly in warp sizing, to enhance yarn strength, lubrication, and weaving efficiency.

Environmental Remediation:
Microcrystalline cellulose can be utilized in environmental remediation processes, such as soil and groundwater remediation, to aid in the adsorption and removal of contaminants.

Ceramics and Glass Industry:
Microcrystalline cellulose is used as a binder and rheology modifier in ceramic and glass fiber production, improving fiber integrity, dispersion, and molding properties.

Foundry Industry:
Microcrystalline cellulose can be added to foundry sands to enhance their flowability, reduce casting defects, and improve the surface finish of metal castings.

Rubber Compounding:
Microcrystalline cellulose is employed in rubber compounding processes to improve dispersion of fillers and additives, enhance processing properties, and optimize the performance of rubber products.

Animal Feed Additives:
Microcrystalline cellulose can be used as a binder and flow enhancer in animal feed formulations, ensuring better pellet formation and improved handling during feed production.

Personal Care Products:
Microcrystalline cellulose finds applications in personal care products such as facial cleansers, body washes, and exfoliating scrubs as a gentle abrasive agent and texture enhancer.

Effervescent Tablets:
Microcrystalline cellulose is used in the production of effervescent tablets to improve their disintegration and dissolution properties, allowing for rapid release and absorption of active ingredients.

Ceramic Cores for Investment Casting:
Microcrystalline cellulose can be utilized as a binder in the production of ceramic cores used in investment casting processes, providing dimensional accuracy and stability during casting.

Thermal Insulation Materials:
Microcrystalline cellulose can be incorporated into thermal insulation materials, such as fiberglass and mineral wool, to enhance their structural integrity and thermal performance.

Synthetic Fiber Production:
Microcrystalline cellulose is used in the production of synthetic fibers, such as rayon and viscose, as a binder and reinforcement agent to improve fiber strength and processability.

Soil Amendment and Agriculture:
Microcrystalline cellulose can be applied to soil as an amendment to improve water retention, nutrient availability, and soil structure, enhancing plant growth and agricultural productivity.

Abrasive and Polishing Compounds:
Microcrystalline cellulose is utilized in abrasive and polishing compounds to provide a mild abrasive action for surface cleaning, smoothing, and polishing applications.

Coating and Encapsulation:
Microcrystalline cellulose can be used as a coating material or encapsulating agent for various purposes, including controlled release of active ingredients, protection against moisture, and improving stability.

Water Treatment:
Microcrystalline cellulose can be utilized in water treatment processes, such as filtration and clarification, to aid in the removal of suspended particles and impurities from water.

Fire Retardant Applications:
Microcrystalline cellulose can be incorporated into fire retardant formulations to improve their flame resistance properties, providing enhanced safety in various applications.



DESCRIPTION


Microcrystalline cellulose is a refined wood pulp or plant fiber that is processed into a fine, white, odorless powder.
Microcrystalline cellulose is primarily composed of cellulose, which is a complex carbohydrate found in the cell walls of plants.
Microcrystalline cellulose is insoluble in water and other common organic solvents.

The chemical formula for microcrystalline cellulose is (C6H10O5)n, where "n" represents the degree of polymerization, which can vary.

Microcrystalline cellulose is a finely powdered substance derived from wood pulp or plant fibers.
Microcrystalline cellulose appears as a white, odorless powder with a fine particle size.
The texture of microcrystalline cellulose is soft and smooth to the touch.

Microcrystalline cellulose has excellent flowability and compressibility properties, making it ideal for tablet manufacturing.
Microcrystalline cellulose is insoluble in water and most organic solvents.
Microcrystalline cellulose is composed primarily of cellulose, a polysaccharide found in plant cell walls.
The particles of microcrystalline cellulose have a crystalline structure on a microscopic level.

Microcrystalline cellulose has a low bulk density, allowing it to be easily incorporated into various formulations.
Microcrystalline cellulose has a high capacity for moisture absorption, which can contribute to its functionality in certain applications.

Microcrystalline cellulose is chemically stable and resistant to microbial degradation.
The pH of microcrystalline cellulose is typically neutral, making it compatible with a wide range of formulations.
Microcrystalline cellulose does not undergo significant changes in viscosity over a wide pH range.
Microcrystalline cellulose is non-toxic and safe for use in various industries, including pharmaceuticals and food.

Microcrystalline cellulose has a long shelf life when stored under appropriate conditions.
Microcrystalline cellulose is a renewable and sustainable material, derived from natural plant sources.
Microcrystalline cellulose has good thermal stability, withstanding a range of temperatures without significant decomposition.
The fine particle size of microcrystalline cellulose contributes to its uniform distribution and dispersion in formulations.
Microcrystalline cellulose has excellent binding properties, allowing it to act as a cohesive agent in tablet compression.

Microcrystalline cellulose has a low hygroscopicity, meaning it does not readily absorb moisture from the environment.
Microcrystalline cellulose exhibits good compatibility with other excipients and active ingredients in pharmaceutical formulations.
The small particle size and uniformity of microcrystalline cellulose contribute to smooth tablet disintegration and dissolution.
Microcrystalline cellulose provides stability to pharmaceutical formulations by preventing segregation and improving homogeneity.

Microcrystalline cellulose is resistant to enzymatic degradation in the gastrointestinal tract, making it suitable for oral dosage forms.
Microcrystalline cellulose can contribute to improved bioavailability of certain drugs by enhancing their dissolution rate.
Microcrystalline cellulose is widely used as a versatile excipient in pharmaceuticals, food products, cosmetics, and other industries due to its unique properties and functionality.



PROPERTIES


Chemical Formula: (C6H10O5)n
Appearance: White, odorless powder
Molecular Weight: Varies depending on the degree of polymerization
Solubility: Insoluble in water and organic solvents
Particle Size: Fine to coarse powder, typically ranging from 20 to 200 microns
Density: Approximately 0.3 to 0.6 g/cm3
pH: Neutral to slightly acidic
Moisture Content: Typically below 10%
Bulk Density: Varies depending on the grade and compaction conditions
Specific Surface Area: Relatively high surface area due to its fibrous structure
Swelling Capacity: Exhibits swelling behavior upon contact with water
Gelation: Can form gels when dispersed in water or certain solvents
Thermal Stability: Stable up to temperatures around 200-250°C
Rheological Properties: Exhibits pseudoplastic or thixotropic behavior, depending on the grade
Water Retention: Has the ability to absorb and retain water
Binding Properties: Excellent binding capacity, especially in tablet formulations
Disintegration: Facilitates rapid disintegration of tablets upon contact with fluids
Flowability: Provides improved flow properties and prevents caking or clumping in powder formulations
Stability: Chemically stable under normal storage and handling conditions
Compatibility: Compatible with a wide range of other excipients and active ingredients
Film Forming: Can form films or coatings with good mechanical strength and barrier properties
Lubricity: Exhibits lubricating properties, aiding in the ease of tablet compression and ejection
Suspension Stability: Can suspend solid particles in liquids without significant settling or sedimentation
Tasteless and Odorless: Does not impart any noticeable taste or odor to formulations
Biocompatibility: Generally regarded as safe for use in pharmaceutical and food applications



FIRST AID


General First Aid:

If any symptoms persist or worsen, seek medical attention promptly.
If medical attention is required, bring the product label or safety data sheet (SDS) with you.
In case of any emergency, contact the appropriate emergency services in your country or region.


Inhalation:

Move the affected person to fresh air and ensure they are in a well-ventilated area.
If respiratory symptoms occur or breathing becomes difficult, seek medical attention immediately.
Provide supportive measures such as oxygen, if necessary.
If the person is not breathing, administer artificial respiration and seek immediate medical attention.


Skin Contact:

Remove contaminated clothing and footwear.
Wash the affected area with soap and water thoroughly for at least 15 minutes.
If irritation persists, seek medical advice and provide information about the substance.


Eye Contact:

Flush the eyes gently with clean water for at least 15 minutes, holding the eyelids open.
Remove contact lenses, if applicable, after rinsing for a few minutes.
Seek immediate medical attention and provide information about the substance.


Ingestion:

Rinse the mouth with water and drink plenty of water to dilute the substance.
Do not induce vomiting unless instructed to do so by medical professionals.
Seek immediate medical attention and provide information about the substance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):

Wear appropriate protective clothing, including gloves, safety goggles, and a lab coat or protective clothing.
Use respiratory protection if there is a risk of inhalation of dust or particles.
Follow good industrial hygiene practices and ensure that PPE is selected based on the specific handling task.

Ventilation:

Ensure adequate ventilation in the handling area to minimize the concentration of airborne particles.
Use local exhaust ventilation or dust collection systems to control dust emissions, especially during processes that generate airborne particles.

Avoid Dust Generation:

Minimize the generation of dust by using appropriate handling techniques, such as controlled pouring, transfer, or mixing.
Use enclosed systems or handling equipment to prevent dust dispersion.

Fire and Explosion Hazards:

Microcrystalline cellulose is not considered flammable or explosive under normal conditions.
However, it may burn if exposed to high heat or open flame.
Take precautions to prevent the accumulation of dust, as high concentrations of airborne dust can form explosive mixtures in the presence of an ignition source.
Storage:

Store in a Dry Environment:

Store microcrystalline cellulose in a cool, dry place, away from moisture and humidity.
Protect the product from exposure to water or excessive moisture, as it may affect its performance and flow properties.
Temperature and Light:

Store at ambient temperatures, typically between 20°C and 25°C (68°F and 77°F).
Protect from direct sunlight and sources of heat to prevent degradation or discoloration of the product.
Packaging and Containment:

Keep the product in its original tightly closed container or packaging to maintain its integrity and prevent contamination.
Ensure that containers are properly labeled with relevant information, including the product name, batch number, and handling precautions.



SYNONYMS


MCC
Cellulose gel
Avicel®
Avicel® PH
Avicel® RC
Avicel® CL
Avicel® PH 101
Avicel® PH 102
Avicel® PH 103
Avicel® PH 105
Avicel® RC 581
Avicel® RC 591
Avicel® RC 591F
Avicel® CE
Avicel® PCW
Avicel® PCL
Vivapur®
Vivapur® 101
Vivapur® 102
Vivapur® 103
Emcocel®
Emcocel® 50M
Emcocel® 90M
Elcema®
Cellactose®
Avicel® PHM
Avicel® DG
Avicel® DG 112
Avicel® DG 581
Avicel® DG 591
Avicel® DG 591F
Avicel® DG PCW
Avicel® DG PCL
Avicel® HFE-5
Avicel® HFE-10
Avicel® SF-200
Avicel® SF-250
Avicel® SF-50
Avicel® SF-100
Avicel® SF-130
Emcocel® 90SH
Emcocel® 90SHX
Emcocel® 200M
Emcocel® 300M
Elcema® 90SH
Elcema® 300M
Vivapur® 105
Vivapur® 110
Cellactose® 80
Cellactose® 80M
Avicel® PC 591
Avicel® PC 611
Avicel® PCW 12
Avicel® PCW 15
Avicel® PCW 19
Avicel® PCW 21
Avicel® PH 112
Avicel® PH 113
Avicel® PH 200
Avicel® PH 205
Avicel® PH 301
Avicel® PH 302
Avicel® PH 306
Avicel® PH 311
Avicel® PH 361
Avicel® PH 367
Vivapur® PH 101
Vivapur® PH 102
Vivapur® PH 103
Vivapur® PH 105
Emcocel® 60M
Emcocel® 70M
Emcocel® 100M
Emcocel® 120M
Elcema® 90M