Textile, Leather, Paper and Industrial Chemicals

Isopropyl benzoate
ISOPROPYL ISOSTEARATE, N° CAS : 31478-84-9 / 68171-33-5. Nom INCI : ISOPROPYL ISOSTEARATE. Nom chimique : Isopropyl isodecanoate. N° EINECS/ELINCS : 250-651-1 / 269-023-3. Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Emollient : Adoucit et assouplit la peau. Agent d'entretien de la peau : Maintient la peau en bon état
ISOPROPYL BROMIDE
Isopropyl bromide is also known as 75-26-3, 2-bromo-propane, 2-Bromopropane, Propan-2-bromo with Molecular Formula of C3H7Br and Molecular Weight of 122.99168.
Isopropyl bromide is manufactured by heating isopropyl alcohol with HBr and is available in colorless liquid form.
Isopropyl bromide is also used as an intermediate to form alkylated amines and alkylated metallic compounds.

CAS Number: 75-26-3
EC Number: 200-855-1
Molecular Formula: 13C3H7Br
Molecular Weight: 125.97

Isopropyl bromide, also known as 2-Bromopropane and 2-propyl bromide, is the halogenated hydrocarbon with the formula CH3CHBrCH3.
Isopropyl bromide is a colorless liquid.

Isopropyl bromide is used for introducing the isopropyl functional group in organic synthesis.
Isopropyl bromide is prepared by heating isopropanol with hydrobromic acid.

Isopropyl bromide serves as an alkylating agent in organic synthesis.
Isopropyl bromide is also used as an intermediate to form alkylated amines and alkylated metallic compounds.

Further, Isopropyl bromide acts as a solvent for industrial cleaning, degreasing, metal processing and finishing, electronics, aerospace and aviation, aerosols, textiles, adhesives and inks.
In addition, Isopropyl bromide is used for introducing the isopropyl functional group in organic synthesis.

Isopropyl Bromide is also known as 75-26-3, 2-bromo-propane, 2-Bromopropane, Propan-2-bromo with Molecular Formula of C3H7Br and Molecular Weight of 122.99168.
Isopropyl bromide is manufactured by heating isopropyl alcohol with HBr and is available in colorless liquid form.

Isopropyl bromide is an organobromide compound.
Isopropyl bromide is used for introducing the isopropyl functional group in organic synthesis.

Isopropyl bromide is sometimes used as an alternative to ozone-depleting cleaning solvents such as chlorofluorocarbons.
Isopropyl bromide is prepared by heating isopropanol with hydrobromic acid.

Isopropyl Bromide is also known as 75-26-3, 2-bromo-propane, 2-Bromopropane, Propan-2-bromo with Molecular Formula of C3H7Br and Molecular Weight of 122.99168.
Isopropyl bromide is manufactured by heating isopropyl alcohol with HBr and is available in colorless liquid form.

Some of Isopropyl bromide properties include Boiling Point of 59-60°C, Melting Point of -89.0°C, Density/Specific Gravity of 1.31 at 20°C/4°C with miscible solubility with chloroform, ether, alcohol, benzene; slight solubility in acetone and in water (3,180 mg/L at 20°C).
Further, Isopropyl bromide has Surface Tension of 3.5348X10-2 N/m at melting point, Vapor Density of 4.27 (Air=1) and Vapor Pressure of 216 mm Hg at 25°C.

Isopropyl bromide, also known as 2-Bromopropane or 2-propyl bromide, is used for introducing the isopropyl functional group in organic synthesis.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.

Isopropyl bromide has proved to be a useful reagent for amino acids dissolved in dimethylsulfoxide/sodium hydride, except for the determination of arginine.
Methylation of acids with diazomethane has also been used for metabolic profiling despite the formation of artefacts.

Resin-mediated methylation of polyfunctional acids found in fruit juices has also proved successful.
Fumaric, succinic, malic, tartaric, isocitric and citric acids, isolated from fruit juices by trapping onto anionic ion exchange resins, can be efficiently converted to methyl esters by reaction with methyl iodide in both supercritical carbon dioxide and acetonitrile.

To provide for the analysis of even short chain fatty acids in serum, a procedure has been developed with benzyl bromide.
This has been successfully employed for serum and urine organic acid profiling.
The method cannot be used for citric acid or sugar-related acids.

Exposure to Isopropyl bromide has been associated with adverse reproductive effects in men and women.
There are also some reports suggesting that maternal formaldehyde exposure is related to delayed conception and miscarriage, and exposure to trinitrotoluene or trichloroethylene may be harmful for the reproductive health of men.
Formamide, dimethylformamide and n-methyl-2-pyrrolidone have also been shown to cause fetotoxic and teratogenic effects in laboratory animals, but there are no data on their effects in humans.

In summary, the epidemiologic evidence suggests that high maternal exposure to solvents may represent a hazard for the developing fetus and may impair female fertility.
The results for male fertility are less conclusive.

The findings on individual solvents must also be interpreted with caution, because coincident exposure to several agents makes Isopropyl Bromide difficult to ascribe adverse effects to a specific compound.
Nevertheless, the study results are supportive of adverse effects of some glycol ethers, tetrachloroethylene, toluene, benzene and carbon disulfide on reproduction.
Isopropyl Bromide would be prudent to minimize exposure to organic solvents.

Some of Isopropyl Bromide properties include Boiling Point of 59-60°C, Melting Point of -89.0°C, Density/Specific Gravity of 1.31 at 20°C/4°C with miscible solubility with chloroform, ether, alcohol, benzene; slight solubility in acetone and in water (3,180 mg/L at 20°C).
Further, Isopropyl Bromide has Surface Tension of 3.5348X10-2 N/m at melting point, Vapor Density of 4.27 (Air=1) and Vapor Pressure of 216 mm Hg at 25°C.

Isopropyl bromide, also known as 2-Bromopropane and 2-propyl bromide, is the halogenated hydrocarbon with the formula CH3CHBrCH3.
Isopropyl Bromide is a colorless liquid.

Isopropyl Bromide is used for introducing the isopropyl functional group in organic synthesis.
Isopropyl bromide is prepared by heating isopropanol with hydrobromic acid.

Applications of Isopropyl bromide:
Isopropyl bromide is used for introducing the isopropyl functional group in organic synthesis.
Isopropyl bromide is also used as an intermediate to form alkylated amines and alkylated metallic compounds.

Further, Isopropyl bromide acts as a solvent for industrial cleaning, degreasing, metal processing and finishing, electronics, aerospace and aviation, aerosols, textiles, adhesives and inks.
In addition, Isopropyl bromide is used for introducing the isopropyl functional group in organic synthesis.

Isopropyl bromide is the insecticide fenvalerate, fenvalerate, propoxur, bactericide, rustamine, fluoroamide and herbicide, an intermediate of the phosphorus of sarcandra.
Isopropyl bromide is used in organic synthesis and pharmaceutical industry

Isopropyl bromide is used in organic synthesis and pharmaceutical, pesticide intermediates
Isopropyl bromide is used as Grignard reagents and raw materials, intermediates of drugs and dyes are also used in the manufacture of pesticides (bisulfate) and the like.

Uses of Isopropyl bromide:
Isopropyl bromide serves as an alkylating agent in organic synthesis.
Isopropyl bromide is also used as an intermediate to form alkylated amines and alkylated metallic compounds.

Further, Isopropyl bromide acts as a solvent for industrial cleaning, degreasing, metal processing and finishing, electronics, aerospace and aviation, aerosols, textiles, adhesives and inks.
In addition, Isopropyl bromide is used for introducing the isopropyl functional group in organic synthesis.

Isopropyl bromide is used as a freon substitute.
Isopropyl bromide is used in organic synthesis.

Isopropyl bromide is used in the synthesis of pharmaceuticals, dyes and other organics.
Isopropyl bromide is an industrial and laboratory chemical.

Industry Uses:
Intermediates

Industrial Processes with risk of exposure:
Metal Degreasing

Nature of Isopropyl bromide:
Isopropyl bromide is colorless volatile liquid.
Isopropyl bromide is relative density is 1. 3140(20 ℃).

Isopropyl bromide is melting Point -89 °c.
Isopropyl bromide is boiling Point 59. 38 °c.

Isopropyl bromide is refractive index 1.4251(20 degrees C).
Isopropyl bromide is slightly soluble in water, with alcohol, ether, benzene, chloroform miscible.

Preparation of Isopropyl bromide:
Isopropyl bromide is commercially available.
Isopropyl bromide may be prepared in the ordinary manner of alkyl bromides, by reacting isopropanol with phosphorus and bromine, or with phosphorus tribromide.

Production Method of Isopropyl bromide:
From isopropyl alcohol and hydrobromic acid reaction.
Slowly add isopropyl alcohol into concentrated sulfuric acid under cooling, control the temperature below 30 ℃, add hydrobromic acid after adding, slowly heat and reflux for 4H, and then distill the appearance of oil droplets, the obtained crude product was washed with concentrated sulfuric acid, water and 5% sodium carbonate respectively, then dried, filtered and fractionated with anhydrous sodium carbonate, and the 58.5-60.5 ° C.

Fraction was collected as the finished product.
In addition, there is an isopropyl alcohol-sodium bromide method.
The preparation method is derived from the reaction of isopropyl alcohol and hydrobromic acid.

The reaction equation is as follows:
(CH3)2CHOH + HBr[H2SO4]→(CH3)2CHBr + H2O

Isopropanol is slowly added to concentrated sulfuric acid under cooling, and the temperature is controlled below 30 ℃, after the addition, hydrobromic acid was added, and the mixture was slowly heated and refluxed for 4 h, then distilled until oil droplets appeared.
The crude product was washed with concentrated sulfuric acid, water and 5% sodium carbonate respectively, and then dried with anhydrous sodium carbonate, filtration, fractionation, collection of 58.5~60.5 °c fraction, that is, the finished product.

MeSH Pharmacological Classification of Isopropyl bromide:

Solvents:
Liquids that dissolve other substances (solutes), generally solids, without any change in chemical composition, as, water containing sugar.

Mutagens:
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids.
A clastogen is a specific mutagen that causes breaks in chromosomes.

Stability and Reactivity of Isopropyl bromide:

Reactive Hazard:
None known, based on information available

Stability:
Stable under normal conditions.

Conditions to Avoid:
Incompatible products.
Excess heat.
Keep away from open flames, hot surfacesandsources of ignition.

Incompatible Materials:
Strong oxidizing agents, Strong bases

Hazardous Decomposition Products:
Carbon monoxide (CO), Carbon dioxide (CO2)

Hazardous Polymerization:
Hazardous polymerization does not occur.

Hazardous Reactions:
None under normal processing

Handling and Storage of Isopropyl bromide:

Handling:
Use only under a chemical fume hood.
Wear personal protective equipment/faceprotection.

Do not get in eyes, on skin, or on clothing.
Keep away from open flames, hot surfaces and sources of ignition.

Use only non-sparking tools.
Use spark-proof tools and explosion-proof equipment.

Do not breathe (dust, vapor, mist, gas).
Do not ingest.

If swallowed then seek immediate medical assistance.
Take precautionary measures against static discharges.
To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment mustbe grounded.

Storage:
Keep containers tightly closed in a dry, cool and well-ventilated place.
Keep away from heat, sparks and flame.

Storage Conditions:
Materials which are toxic as stored or which can decompose into toxic components should be stored in a cool, well ventilated place, out of the direct rays of the sun, away from areas of high fire hazard, and should be periodically inspected.
Incompatible materials should be isolated.

Safety of Isopropyl bromide:
Short-chain alkyl halides are often carcinogenic.

The bromine atom is at the secondary position, which allows the molecule to undergo dehydrohalogenation easily to give propene, which escapes as a gas and can rupture closed reaction vessels.
When this reagent is used in base catalyzed reactions, potassium carbonate should be used in place of sodium or potassium hydroxide.

Fire Fighting Procedures of Isopropyl bromide:

If material on fire or involved in fire:
Do not extinguish fire unless flow can be stopped.
Use water in flooding quantities as fog.

Solid streams of water may be ineffective.
Cool all affected containers with flooding quantities of water.

Use alcohol foam, dry chemical or carbon dioxide.
Keep run-off water out of sewers and water sources.

Accidental Release Measures of Isopropyl bromide:

Disposal Methods of Isopropyl bromide:
At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision.
Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Preventive Measures of Isopropyl bromide:

If material on fire or involved in fire:
Do not extinguish fire unless flow can be stopped.
Use water in flooding quantities as fog.

Solid streams of water may be ineffective.
Cool all affected containers with flooding quantities of water.

Use alcohol foam, dry chemical or carbon dioxide.
Keep run-off water out of sewers and water sources.

Personnel protection:
Avoid breathing vapors.
Do not handle broken packages unless wearing appropriate personal protective equipment.
If contact with the material anticipated, wear appropriate chemical protective clothing.

Identifiers of Isopropyl bromide:
CAS Number: 75-26-3
Beilstein Reference: 741852
ChEMBL: ChEMBL451810
ChemSpider: 6118
ECHA InfoCard: 100.000.778
EC Number: 200-855-1
PubChem CID: 6358
RTECS number: TX4111000
UNII: R651XOV97Z
UN number: 2344
CompTox Dashboard (EPA): DTXSID7030197
InChI: InChI=1S/C3H7Br/c1-3(2)4/h3H,1-2H3
Key: NAMYKGVDVNBCFQ-UHFFFAOYSA-N
SMILES: CC(C)Br

Catalogue Number: B687191
CAS Number: 220505-11-3
Molecular Formula: ¹³C₃H₇Br
Molecular Weight: 125.97

Properties of Isopropyl bromide:
Chemical formula: C3H7Br
Molar mass: 122.993 g·mol−1
Appearance: Colorless liquid
Density: 1.31 g mL−1
Melting point: −89.0 °C; −128.1 °F; 184.2 K
Boiling point: 59 to 61 °C; 138 to 142 °F; 332 to 334 K
Solubility in water: 3.2 g L−1 (at 20 °C)
log P: 2.136
Vapor pressure: 32 kPa (at 20 °C)
Henry's law
constant (kH): 1.0 μmol Pa−1 mol−1
Refractive index (nD): 1.4251
Viscosity: 0.4894 mPa s (at 20 °C)

Physical State Liquid
Appearance: Colorless, Light brown
Odor: Odorless
Odor Threshold: No information available
pH: No information available
Melting Point/Range: -89 °C / -128.2 °F
Boiling Point/Range: 59 °C / 138.2 °F @ 760 mmHg
Flash Point: 1 °C / 33.8 °F
Evaporation Rate: No information available
Flammability (solid,gas): Not applicable
Flammability or explosive limits:
Upper: No data available
Lower: 4.6 vol %
Vapor Pressure: 224 mbar @ 20 °C
Vapor Density: No information available
Specific: Gravity 1.310
Solubility: No information available
Partition coefficient; n-octanol/water: No data available
Autoignition: Temperature No information available
Decomposition: Temperature 251 °C
Viscosity: No information available
Molecular Formula: C3 H7 Br
Molecular Weight: 122.99

Physical State: Liquid
Usage: Commerical
Purity: 99% min
Boiling Point: 58-60degree C
Moisture: 0.5% max
Density: 1.31(w/w)

Molecular Weight: 122.99
XLogP3-AA: 1.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 0
Rotatable Bond Count: 0
Exact Mass: 121.97311
Monoisotopic Mass: 121.97311
Topological Polar Surface Area: 0 Ų
Heavy Atom Count: 4
Complexity: 10.8
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Isopropyl bromide:
Product Name: ISO Propyl Bromide/(2 Bromopropane)
Cas No: 75-26-3
Assay: 99% MIN
Test: Standard
Colour: Colourless liquid
Density: 1.31(w/w)
Moisture: 0.5% max
Boiling Point: 58-60°C
Purity: 99% min

Appearance (Clarity): Clear
Appearance (Colour): Colourless to pale yellow
Appearance (Form): Liquid
Colour (APHA): max. 30
Assay (GC): min. 99%
Density (g/ml) @ 20°C: 1.305-1.315
Refractive Index (20°C): 1.424-1.425
Boiling Range: 58-60°C
Stabilizer (Ag wire): Present

Thermochemistry of Isopropyl bromide:
Heat capacity (C): 135.6 J K mol−1
Std enthalpy of formation (ΔfH⦵298): −129 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −2.0537–−2.0501 MJ mol−1

Related compounds of Isopropyl bromide:

Related alkanes:
Bromoethane
1-Bromopropane
tert-Butyl bromide
1-Bromobutane
2-Bromobutane

Related Products of Isopropyl bromide:
Hydroxynorketamine-d6 Hydrochloride
(S)-Ketamine-d6 Hydrochloride
Norketamine-d4
S-(-)-Norketamine-d6 Hydrochloride
Phencyclidine-d5 Hydrochloride

Names of Isopropyl bromide:

Preferred IUPAC name:
2-Bromopropane

Other name:
Isopropyl bromide

Synonyms of Isopropyl bromide:
2-Bromopropane
75-26-3
ISOPROPYL BROMIDE
Propane, 2-bromo-
Isopropylbromide
2-BROMO-PROPANE
sec-Propyl bromide
2-bromo propane
UN2344
R651XOV97Z
MFCD00000147
CCRIS 7919
HSDB 623
EINECS 200-855-1
UNII-R651XOV97Z
i-propylbromide
AI3-18127
2-brompropan
iso-propylbromide
i-propyl bromide
2-bromanylpropane
2-propyl bromide
1-isopropylbromide
iso-propyl bromide
i-PrBr
iso-C3H7Br
1-bromo-1-methylethane
2-Bromopropane, 99%
EC 200-855-1
2-Bromopropane [UN2344] [Flammable liquid]
2-Bromopropane, >=99%
SCHEMBL10251
ISOPROPYL BROMIDE [MI]
CHEMBL451810
DTXSID7030197
2-Bromopropane, analytical standard
AMY37129
ZINC2041293
Tox21_200356
BBL027287
BR1118
STL146524
AKOS000119846
UN-2344
CAS-75-26-3
NCGC00091451-01
NCGC00091451-02
NCGC00257910-01
VS-08520
2-Bromopropane, purum, >=99.0% (GC)
B0639
FT-0611602
EN300-20069
D87619
A838364
Q209323
J-508539
F0001-1897

MeSH Entry Terms of Isopropyl bromide:
2-bromopropane
isopropyl bromide
Isopropyl Bromide
Isophorone diamine; IPDA; aminomethyl-5;chemamminaca17;aralditehy5083;Isophorondiamin cas no: 2855-13-2
ISOPROPYL CHLOROFORMATE
cas no 108-23-6 Isopropoxycarbonyl chloride; Carbonochloridic acid, 1-methylethyl ester; Isopropyl chlorocarbonate; Carbonochloridic acid, isopropyl ester; Formic acid, chloro-, isopropyl ester;
ISOPROPYL HYDROXYLAMINE IPHA
DESCRIPTION:
CAS: 5080-22-8
European Community (EC) Number: 225-791-1
IUPAC Name: N-propan-2-ylhydroxylamine
Molecular Formula: C3H9NO


CHEMICAL AND PHYSICAL PROPERTIES OF ISOPROPYL HYDROXYLAMINE IPHA:
Molecular Weight 75.11
XLogP3-AA 0.1
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 1
Exact Mass 75.068413911
Monoisotopic Mass 75.068413911
Topological Polar Surface Area 32.3 Ų
Heavy Atom Count 5
Formal Charge 0
Complexity 20.9
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Product Name: N-Isopropyl Hydroxylamine (IPHA)
Synonyms: N-isopropylhydroxylamine; 5080-22-8; 2-Propanamine, N-hydroxy-; N-(propan-2-yl)hydroxylamine; N-hydroxypropan-2-amine; N-Isopropylhydroxylamine oxalate salt; N-hydroxypropan-2-amine; N-hydroxypropan-2-amine sulfate (2:1)
CAS NO.: 5080-22-8
EINECS No.: 225-791-1
Molecular Formula: (CH3)2CHNH(OH)
Package: 170 kg plastic lined iron drum
Molecular weight: 75.11
Flashing point: ≥95°C
Density: 1 g/ml
Refractive power: 1.3570
Freezing point: -3°C
PH: 10.6-11.2
Appearance: Clear liquid / White powder
Color: ≤ 200
Purity( ≥ %): 15
Moisture(≤ %): 85
Classification: Textile Auxiliary Agents
Cas NO.: 5080-22-8
Name: N-Isopropylhydroxylamine
Molecular Formula: C3H9NO
Melting Point: 159℃
Boiling Point: 104.9°Cat760mmHg
Refractive index:1.411 (Predicted)
Flash Point: 44.5°C
Purity: 15%
usage: a: used as ethylene monomer b: used as high effective restrainer c: very excellent termina
Density 0.9±0.1 g/cm3
Boiling Point 104.9±23.0 °C at 760 mmHg
Melting Point 159ºC
Molecular Formula C3H9NO
Molecular Weight 75.110
Flash Point 44.5±13.2 °C
Exact Mass 75.068413
PSA 32.26000
LogP 0.40
Vapour Pressure 16.5±0.4 mmHg at 25°C
Index of Refraction 1.411

APPLICATIONS OF N-ISOPROPYL HYDROXYLAMINE (IPHA):
ISOPROPYL HYDROXYLAMINE IPHA is Highly efficient short stopping agent for free radical emulsion polymerization reactions.
ISOPROPYL HYDROXYLAMINE IPHA is An effective oxygen scavenger/passivating agent in boiled water treatment applications.
ISOPROPYL HYDROXYLAMINE IPHA is A hydrazine alternative.





SAFETY INFORMATION ABOUT ISOPROPYL HYDROXYLAMINE IPHA:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.






SYNONYMS OF ISOPROPYL HYDROXYLAMINE IPHA:
2-hydroxylaminopropane
2-hydroxylaminopropane sulfate (2:1)
N-isopropylhydroxylamine
5080-22-8
2-Propanamine, N-hydroxy-
n-hydroxypropan-2-amine
N-propan-2-ylhydroxylamine
ISOPROPYLHYDROXYLAMINE
DTXSID6063694
3NT440V34T
N-(propan-2-yl)hydroxylamine
2-Hydroxylaminopropane
N-Hydroxyisopropylamine
UNII-3NT440V34T
EINECS 225-791-1
IPHA
isopropyl hydroxylamine
N-Isopropyl-hydroxylamine
N-Isopropylhydroxylamine #
EC 225-791-1
ISOPROPYL HYDROXYAMINE
CHEMBL140282
N-HYDROXY-2-PROPANAMINE
N-HYDROXY-2-PROPANEAMINE
HYDROXYLAMINE, N-ISOPROPYL-
ZINC1677558
MFCD02874394
AKOS006230300
AT14836
FT-0719142
EN300-112062
Q27257766
N-ISOPROPYLHYDROXYLAMINE (15% SOLUTION IN WATER)
Z1198161074
n-isopropylhydroxylamine;n-hydroxypropan-2-amine;2-propanamine, n-hydroxy-;2-hydroxylaminopropane;n-isopropylhydroxylamine n-hydroxypropan-2-amine 2-propanamine, n-hydroxy- 2-hydroxylaminopropane


ISOPROPYL ISOSTEARATE
Isopropyl isostearate is a useful research compound.
Isopropyl isostearate's molecular formula is C21H42O2 and its molecular weight is 326.6 g/mol.


CAS Number: 31478-84-9 / 68171-33-5
EC Number: 250-651-1 / 269-023-3
MDL Number: MFCD00038718
Chem/IUPAC Name: Isopropyl isodecanoate
Molecular Formula: C21H42O2



Isopropyl isostearate, 68171-33-5, Nikkol IPIS, Wickenol 131, 31478-84-9, Isopropyl 16-methylheptadecanoate, propan-2-yl 16-methylheptadecanoate,
Isooctadecanoic acid, 1-methylethyl ester, C67IXB9Y7T, 2-Propyl isooctadecanoate, Isostearic acid, isopropyl ester, 1-Methylethyl isooctadecanoate,
Isopropyl isodecanoate, EINECS 250-651-1, ISOPROPYLISOSTEARATE, UNII-C67IXB9Y7T, EINECS 269-023-3, IPIS, CRODAMOL IPIS, DERMOL IPIS, JEECHEM IPIS, NIKKOL EPIS, UNIMATE IPIS, MATLUBE II, DUB ISIP, SCHERCEMOL 318, LANESTA 10, EC 269-023-3, PRISORINE 2021, WITCONOL 2310, SCHERCEMOL 318 ESTER, Heptadecanoic acid, 16-methyl-, 1-methylethyl ester, isostearic acid isopropyl ester, PRISORINE IPIS 2021, SCHEMBL8088310, AEC ISOPROPYL ISOSTEARATE, DTXSID101015768, i-Propyl 16-methyl-heptadecanoate, ISOPROPYL ISOSTEARATE [II], ISOPROPYL ISOSTEARATE [INCI], ISOPROPYL ISOSTEARATE [USP-RS], ISOPROPYL ISOSTEARATE [WHO-DD], ISOPROPYL ISOSTEARATE [EP MONOGRAPH], FT-0641164, NS00008061, Q27275243, Isopropyl Isostearate, T/N Unipro IPIS, TN: Dermol IPIS, Jeechem IPIS, 1-Methylethyl isooctadecanoate, Unipro IPIS, Nikkol IPIS, Wickenol 131, nikkolipis,wickenol131,Einecs 250-651-1,ISOPROPYL ISOSTEARATE,isopropyl isodecanoate,2-Propylisooctadecanoate,Isopropyl isostearate CRS,1-methylethylisooctadecanoate,Isostearicacid,isopropylester,propan-2-yl 16-methylheptadecanoate, Isostearic acid, isopropyl ester,1-Methylethyl isooctadecanoate,Isooctadecanoic acid,1-methylethyl ester,Nikkol IPIS,2-Propyl isooctadecanoate,Prisorine IPIS 2021,propan-2-yl 16-methylheptadecanoate,Unimate IPIS,Isooctadecanoic acid, 1-methylethyl ester,Wickenol 131,HEPTADECANOIC ACID, 16-METHYL-, ISOPROPYL ESTER, Isopropyl 16-Methylheptadecanoate, Isostearic Acid, Isopropyl Ester, Propan-2-yl 16-Methylheptadecanoate,
Isopropyl isostearate,Heptadecanoic acid, 16-methyl-, isopropyl ester, Isooctadecanoic acid, 1-methylethyl ester, Isopropyl isodecanoate



Isopropyl isostearate is a synthetic ingredient very commonly used in cosmetics and personal care products.
Isopropyl isostearate appears as a clear, colorless liquid that belongs to the ester family.
Primarily, Isopropyl isostearate acts as a lubricant, providing a smooth and silky texture to products.


Isopropyl isostearate also functions as an emollient, helping to soften and moisturize the skin.
Additionally, Isopropyl isostearate can enhance the spreadability of formulations, allowing them to be easily applied and absorbed.
Due to its lightweight and non-greasy nature, Isopropyl isostearate is often used in lotions, creams, serums, and makeup products.


The chemical formula of Isopropyl isostearate is C21H42O2.
Isopropyl isostearate is an Ester of isopropyl alcohol and isostearic acid.
The exact mass of Isopropyl isostearate is unknown and the complexity rating of the compound is unknown.


Isopropyl isostearate is an oily liquid (ester) that makes your skin nice and smooth, aka emollient.
Isopropyl isostearate is described as highly emollient or substantive, but with a light and easy spreading and nonoily skin feel.
Isopropyl isostearate is a lipid synthesized via a reaction between isopropyl alcohol and isostearic acid, a type of fatty acid.


Isopropyl isostearate is the ester of isopropyl alcohol.
Isopropyl isostearate is an organic compound formed by the reaction of an acid with an alcohol.
Alcohols are a large class of important cosmetic ingredients but only ethanol needs to be denatured to prevent Isopropyl isostearate from being redirected from cosmetic applications to alcoholic beverages.


Isopropyl isostearate is a liquid.
Isopropyl isostearate is fatty ester derived from renewable vegetable oils.
Saponification value of Isopropyl isostearate is 160-180.


Isopropyl isostearate is a colorless to light yellow oily liquid
Isopropyl isostearate is a colorless to slightly yellow transparent liquid
Isopropyl isostearate is an emollient that leaves the skin surface with a smooth and supple finish.


Isopropyl isostearate also acts as a binder.
Isopropyl isostearate is a derivative of isostearic acid.
Isopropyl isostearate is a non flammable.



USES and APPLICATIONS of ISOPROPYL ISOSTEARATE:
Isopropyl isostearate is used Cosmetics -> Binding; Emollient; Skin conditioning.
Isopropyl isostearate uses and applications include: Emollient, lubricant, solubilizer for bath oils, creams, lotions, shampoos; binder for pressed powder; emollient, emulsifier, thickener, stabilizer, opacifier, pearlescent for creams, shaving creams, cream shampoos.


Isopropyl isostearate has many uses in the personal care and cosmetic industry.
Isopropyl isostearate is a great emollient that provides intense moisturization and hydration to the skin.
Isopropyl isostearate also forms a protective barrier that helps prevent water loss, keeping the skin soft and supple.


Because it is lightweight and non-greasy, Isopropyl isostearate does not feel heavy on the surface of the skin and lets it breathe.
In products like creams, serums, and lotions, Isopropyl isostearate improves the spreadability and absorption to allow for an easier application and a smooth finish.


Isopropyl isostearate is also added to makeup formulations such as foundations, lipsticks, and eyeshadows, where it enhances the blend-ability and adherence of the products.
In cosmetics and personal care products, Isopropyl isostearate is used in the formulation of skin care products and face and eye makeup.


Isopropyl isostearate is a fast spreading emollient suitable for all cosmetic applications.
Isopropyl isostearate is the ester of isopropyl alcohol and isostearic acid.
Isopropyl isostearate is used as a skin-softening agent and emollient in cosmetics products, retaining none of the sensitizing potential pure isopropyl alcohol has.


Isopropyl isostearate is a liquid, non-ionic emollient derived from isostearic acid that offers superb moisturization characteristics.
This light, easy-spreading emollient, Isopropyl isostearate, is particularly suited to face creams and other applications where skin moisturization is of high importance.


As a highly effective makeup solvent, Isopropyl isostearate also has outstanding performance in makeup removers and foundations.
Isopropyl isostearate is a low viscosity, fast spreading emollient.
Isopropyl isostearate finds application in formulating antiperspirants, deodorants, baby-care & cleansers, facial- & body-care products, color-care and sun-care (sun-protection, after-sun & self-tanning) products.


Recommended use level of Isopropyl isostearate is 1-5%.
Isopropyl isostearate is used for external use only.
Isopropyl isostearate offers good moisturizing, long-lasting and lubricious skin feel.


Isopropyl isostearate is a good solvent for makeup removers and foundations.
Isopropyl isostearate is used as a binder for decorative cosmetics.
Isopropyl isostearate offers excellent low temperature properties and exhibit good oxidative stability, due to the saturated and branched molecular structure.


Isopropyl isostearate has remarkably high miscibility and compatibility in a wide range of formulations with ester oils, silicone-based emulsifiers and color pigments.
Isopropyl isostearate is used Skin and hair care products, color cosmetics
Isopropyl isostearate is used Treatment / Conditioner, Milk / Cream / Serum, and Suncare


Isopropyl isostearate is used Lubrication of the skin, gives a soft and smooth appearance.
Isopropyl isostearate acts as a light-textured emollient with low occlusivity, good permeation and spreadability.
Cosmetic Uses of Isopropyl isostearate: binding agents, skin conditioning, and skin conditioning - emollient



FUNCTIONS OF ISOPROPYL ISOSTEARATE:
*Binding agent :
Isopropyl isostearate allows the cohesion of different cosmetic ingredients
*Emollient :
Isopropyl isostearate softens and smoothes the skin
*Skin conditioning :
Isopropyl isostearate maintains skin in good condition



ORIGIN OF ISOPROPYL ISOSTEARATE:
Isopropyl isostearate is typically made by esterifying isostearic acid with isopropyl alcohol.
This process involves combining the acid and alcohol in the presence of a catalyst, resulting in the formation of Isopropyl isostearate and water.
The reaction is then followed by purification steps to obtain the desired product.



SAFETY PROFILE OF ISOPROPYL ISOSTEARATE:
Isopropyl isostearate is considered safe for cosmetic use.
Isopropyl isostearate has a low comedogenic rating, so it is unlikely to cause acne and breakouts.



ALTERNATIVES OF ISOPROPYL ISOSTEARATE:
CAPRYLIC CAPRIC TRIGLYCERIDE,
ETHYLHEXYL PALMITATE,
DIMETHICONE



FUNCTION OF ISOPROPYL ISOSTEARATE:
Isopropyl isostearate is an emoliient that leaves the skin surface with a smooth and supple finish.
Isopropyl isostearate also acts as a binder.



FEATURES OF ISOPROPYL ISOSTEARATE:
*Low viscosity oil with light and dry feeling.
*Good solubilizing capacity of UV absorbers.
*Reduce frictions of damaged hair.



WHAT DOES ISOPROPYL ISOSTEARATE DO IN A FORMULATION?
*Binding
*Emollient
*Moisturising
*Skin conditioning



WHY IS ISOPROPYL ISOSTEARATE USED?
Isopropyl isostearate acts as a lubricant on the skin’s surface giving it a soft and smooth appearance.
Isopropyl isostearate may also act as a binder
Isopropyl isostearate is used ingredients that hold together the ingredients of a compressed tablet or cake.



SCIENTIFIC FACTS OF ISOPROPYL ISOSTEARATE:
Isopropyl isostearate is made from isopropyl alcohol and stearic acid.
Stearic acid is naturally occurring and is found in animal and vegetable fats.



FUNCTION OF ISOPROPYL ISOSTEARATE:
*An emollient
Isopropyl isostearate is the ester of Isopropyl Alcohol and Isostearic Acid(CosmeticsInfo.org).
Isopropyl isostearate is used in beauty products as an emollient, skin conditioning agent, binder and humectant.
Isopropyl isostearate helps lock in moisture and gives skin a smooth feel, and acts as a lubricant on the skin's surface to give it a soft and silky appearance.



PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL ISOSTEARATE:
Boiling Point: 360.7°C
Melting Point: 18.45°C
pH: Neutral
Solubility: Partially soluble in water
Viscosity: Low
Molecular Weight: 326.6 g/mol
XLogP3-AA: 9
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 17
Exact Mass: 326.318480578 g/mol

Monoisotopic Mass: 326.318480578 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 23
Formal Charge: 0
Complexity: 259
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Physical state: liquid

Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/freezing point: < 0 °C at ca.1.013 hPa
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: No data available
Autoignition temperature: 240 °C at 1.001 - 1.012 hPa
Decomposition temperature: No data available
pH: No data available

Viscosity
Viscosity, kinematic: 13,138 mm2/s at 20 °C7,121 mm2/s at 40 °C
Viscosity, dynamic: No data available
Water solubility 0,0015 g/l at 20 °C
Partition coefficient: n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: Not classified as explosive.
Oxidizing properties: none
Other safety information: No data available

Chemical Class: Fatty Acid Esters , Polybasic Acid Esters
CAS Number: 31478-84-9
EINECS: 42-501013
Appearance: Colorless to light yellow liquid
Melting point: 18.45°C (estimate)
Boiling point: 364.57°C (rough estimate)
Density: 0.8760 (rough estimate)
refractive index: 1.4304 (estimate)
Viscosity: 13.14mm2/s
EWG's Food Scores: 1
FDA UNII: C67IXB9Y7T
EPA Substance Registry System: Isopropyl isostearate (68171-33-5)

Name:Isopropyl isostearate
EINECS: 269-023-3
CAS No.: 68171-33-5
Density: 0.86 g/cm3
PSA: 26.30000
LogP: 7.05540
Solubility: N/A
Melting Point: 18.45°C (estimate)
Formula: C21H42O2
Boiling Point: 360.7 °Cat760mmHg
Molecular Weight: 326.63
Flash Point: 183.6 °C
Transport Information: N/A
Appearance: N/A
Safety: Risk Codes: N/A

EINECS: 269-023-3
IUPAC Name: Propan-2-yl 16-methylheptadecanoate
Molecular Formula: C21H42O2
Molecular Weight: 326.556980 g/mol
XLogP3-AA: 9
H-Bond Acceptor: 2
Canonical SMILES: CC(C)CCCCCCCCCCCCCCC(=O)OC(C)C
InChI: InChI=1S/C21H42O2/c1-19(2)17-15-13-11-9-7-5-6-8-10-12-14-16-18-21(22)23-20(3)4/h19-20H,5-18H2,1-4H3
InChIKey: NEOZOXKVMDBOSG-UHFFFAOYSA-N
Index of Refraction: 1.445
Molar Refractivity: 101.03 cm3
Molar Volume: 379.4 cm3

Surface Tension: 29.8 dyne/cm
Density: 0.86 g/cm3
Flash Point: 183.6 °C
Enthalpy of Vaporization: 60.65 kJ/mol
Boiling Point: 360.7 °C at 760 mmHg
Vapour Pressure: 2.18E-05 mmHg at 25 °C
Water Solubility of Isopropyl isostearate (CAS NO. 68171-33-5): 0.000155 mg/L at 25 °C
Molecular form: C21H42O2
Appearance: NA
Mol. Weight: 326.57
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NA
BTM: NA



FIRST AID MEASURES of ISOPROPYL ISOSTEARATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOPROPYL ISOSTEARATE:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ISOPROPYL ISOSTEARATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL ISOSTEARATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of ISOPROPYL ISOSTEARATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Store in cool place.
*Storage class:
Storage class (TRGS 510): 12:
Non Combustible Liquids



STABILITY and REACTIVITY of ISOPROPYL ISOSTEARATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



ISOPROPYL ISOSTEARATE
ISOPROPYL LAURATE, N° CAS : 10233-13-3. Nom INCI : ISOPROPYL LAURATE. N° EINECS/ELINCS : 233-560-1. Ses fonctions (INCI) : Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Emollient : Adoucit et assouplit la peau. Agent d'entretien de la peau : Maintient la peau en bon état
ISOPROPYL LAURATE
Isopropyl laurate,Laurate d’isopropyle, IPL,Dodecanoic acid, 1-methylethyl ester, EC / List no.: 233-560-1, CAS no.: 10233-13-3. Mol. formula: C15H30O2 Le Laurate d’isopropyle est produit à partir d’acide laurique dérivé d’huile végétale & d’isopropanol (ou alcool isopropylique). C’est l’ester de l’acide laurique et de l’isopropanol.1-Methylethyl dodecanoate; 233-560-1 [EINECS]; Dodecanoic acid, 1-methylethyl ester ; Isopropyl laurate ; Isopropyllaurat [German] ; Laurate d'isopropyle [French] MFCD00451146 [MDL number]; propan-2-yl dodecanoate; [10233-13-3]; 2-Propanoldodecanoate; 56S; 98-58-8 [RN]; AGN-PC-0JKHZX; Dodecanoic acid 1-methylethyl ester; dodecanoic acid isopropyl ester; Dodecanoic acid methylethyl ester; EINECS 233-560-1; iso-Propyl dodecanoate; Isopropyl dodecanoate; Isopropyl laurate|Propan-2-yl dodecanoate; Isopropyl_laurate; iso-Propyldodecanoate; Isopropyllaurate; Jsp000277; lauric acid isopropyl ester; ST-5309. Isopropyl laurate is used in the following products: washing & cleaning products, polymers, textile treatment products and dyes, adhesives and sealants, lubricants and greases, pH regulators and water treatment products and plant protection products.
ISOPROPYL LAURATE
Isopropyl Laurate is an ester of isopropyl alcohol and lauric acid.
Isopropyl Laurate is a versatile ingredient renowned for its roles as a solubilizer, emulsifier, and emollient.


CAS Number: 10233-13-3
EC Number: 233-560-1
MDL number: MFCD00451146
Chem/IUPAC Name: Isopropyl laurate
Molecular Formula: C15H30O2


Isopropyl Laurate is an ester of isopropyl alcohol and myristic acid (vegetable-derived).
Isopropyl Laurate has a low viscosity fluid non-greasy emollient, tolerates a wide pH range, compatible with most surfactants.
Thanks to its low viscosity and density, Isopropyl Laurate has a high spreadability.


The specific gravity of Isopropyl Laurate is 0.85 (at 20°C).
Isopropyl Laurate is a versatile ingredient renowned for its roles as a solubilizer, emulsifier, and emollient.
Isopropyl Laurate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Isopropyl Laurate is a fatty acid ester obtained by the formal condensation of carboxy group of dodecanoic acid with propan-2-ol. Isopropyl Laurate is a metabolite found in human saliva.
Isopropyl Laurate has a role as a human metabolite.


Isopropyl Laurate is a fatty acid ester and an isopropyl ester.
Isopropyl Laurate is functionally related to a dodecanoic acid.
Isopropyl Laurate is a natural product found in Lonicera japonica with data available.


Isopropyl Laurate is a colorless to pale yellow liquid, is insoluble in water, and has a faint odor.
Isopropyl Laurate is a fatty acid ester obtained by the formal condensation of carboxy group of dodecanoic acid with propan-2-ol.
Isopropyl Laurate has a role as a human metabolite.


Isopropyl Laurate is a fatty acid ester and an isopropyl ester.
Isopropyl Laurate derives from a dodecanoic acid.
Isopropyl Laurate is a non-branched saturated fatty acid ester obtained from isopropanol and lauric acid, from palm oil.
Isopropyl Laurate is a clear liquid with a melting point of 23 ºC.



USES and APPLICATIONS of ISOPROPYL LAURATE:
Isopropyl Laurate is used as a cosmetics deep agent and skin moisturizer, penetrant.
Isopropyl Laurate has excellent penetration, moisturizing and softening effect on the skin, and is used for emulsifiers and moisturizers for cosmetics.
Isopropyl Laurate can be used in cosmetics such as sol product, hair conditioner, skin cream, sunscreen and shaving cream.


Isopropyl Laurate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Isopropyl Laurate is used in the following products: washing & cleaning products, polymers, textile treatment products and dyes, lubricants and greases, adhesives and sealants and pH regulators and water treatment products.


Release to the environment of Isopropyl Laurate can occur from industrial use: in the production of articles and in processing aids at industrial sites.
Other release to the environment of Isopropyl Laurate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Other release to the environment of Isopropyl Laurate is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Isopropyl Laurate can be found in complex articles, with no release intended: vehicles.
Isopropyl Laurate can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), wood (e.g. floors, furniture, toys) and leather (e.g. gloves, shoes, purses, furniture).


Isopropyl Laurate is used in the following products: washing & cleaning products and polishes and waxes.
Isopropyl Laurate is used in the following areas: formulation of mixtures and/or re-packaging.
Isopropyl Laurate is used for the manufacture of: and chemicals.


Other release to the environment of Isopropyl Laurate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Isopropyl Laurate is used in the following products: polymers, washing & cleaning products, lubricants and greases and textile treatment products and dyes.


Release to the environment of Isopropyl Laurate can occur from industrial use: formulation of mixtures and formulation in materials.
Isopropyl Laurate is used in the following products: washing & cleaning products, metal surface treatment products, textile treatment products and dyes, polymers and lubricants and greases.


Isopropyl Laurate is used for the manufacture of: and chemicals.
Release to the environment of Isopropyl Laurate can occur from industrial use: in processing aids at industrial sites, in the production of articles and as processing aid.


Release to the environment of Isopropyl Laurate can occur from industrial use: manufacturing of the substance.
Release to the environment of Isopropyl Laurate can occur from industrial use: in the production of articles and formulation in materials.
Isopropyl Laurate is used in the following areas: formulation of mixtures and/or re-packaging.


Applications of Isopropyl Laurate: Creams, lotions, hand creams, shampoo, shower gels, makeup removers, powders and foundations.
Isopropyl Laurate uses and applications include: Emollient, lubricant, plasticizer, and cosolvent in cosmetics and pharmaceuticals; defoamer in food-contact paperpaperboard; in food-contact textiles


Widely embraced in cosmetics and topical medicine, Isopropyl Laurate finds applications in personal care and beauty care realms, including body care, facial care, hair care, lip care, and skincare.
Isopropyl Laurate's adaptability extends even further, serving as a flavoring agent in the food industry.


Cosmetic formulations of Isopropyl Laurate: binding, skin conditioning, emollient.
Industrial uses of Isopropyl Laurate: manufacturer of washing and cleaning products, polymers, textile treatment products and dyes, adhesives and sealants, lubricants and greases, pH regulators and water treatment products and plant protection products.


Isopropyl Laurate can be used as a flavor and fragrance agent.
Uses of Isopropyl Laurate: Processing aids, specific to petroleum production.
Isopropyl Laurate can be used as cosmetic oily raw materials, and Isopropyl Laurate can also be used as lubricant additives.


Isopropyl Laurate can also be used as a pharmaceutical excipient, as a solvent and penetration enhancer for topical drugs, instead of vegetable oil, as a lubricant and matrix, and used to prepare ointments and creams.


Isopropyl Laurate is recommended to be used in stamping oil solvents (air conditioning aluminum fin oil), base oils and additives for metalworking fluids, solvent-based cleaning agents and water-based cleaning fluids.
Isopropyl Laurate uses and applications include: Emollient, lubricant, plasticizer, and cosolvent in cosmetics and pharmaceuticals; defoamer in food-contact paperpaperboard; in food-contact textiles.



FUNCTIONS OF ISOPROPYL LAURATE:
*Binding agent :
Isopropyl Laurate allows the cohesion of different cosmetic ingredients
*Emollient :
Isopropyl Laurate softens and smoothes the skin
*Skin conditioning :
Isopropyl Laurate maintains skin in good condition
*Conditioner,
*Emollient,
*Re-Fatting Agent



WHAT DOES ISOPROPYL LAURATE DO IN A FORMULATION?
*Binding
*Emollient
*Skin conditioning



FOOD ADDITIVE CLASSES OF ISOPROPYL LAURATE:
*Flavoring Agents



PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL LAURATE:
CAS Number: 10233-13-3
Chem/IUPAC Name: Isopropyl laurate
EINECS/ELINCS No: 233-560-1
Molecular Weight: 242.40 g/mol
XLogP3-AA: 6.1
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 12
Exact Mass: 242.224580195 g/mol
Monoisotopic Mass: 242.224580195 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 17
Formal Charge: 0
Complexity: 176
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance Form: liquid
Odor: No data available
Odor Threshold: No data available
pH: No data available
Melting point/freezing point: No data available
Initial boiling point and boiling range: No data available
Flash point: Not applicable
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: No data available
Vapor density: No data available
Relative density: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water:
log Pow: 6,178
Autoignition temperature: No data available
Decomposition temperature: No data available
Viscosity: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available

Melting point: 4.2°C (estimate)
Boiling point: 285.23°C (estimate)
Density: 0.8536
refractive index: 1.4280
storage temp.: Sealed in dry,Room Temperature
form: liquid
color: Colourless
InChI: InChI=1S/C15H30O2/c1-4-5-6-7-8-9-10-11-12-13-15(16)17-14(2)3/h14H,4-13H2,1-3H3
InChIKey: UJPPXNXOEVDSRW-UHFFFAOYSA-N
SMILES: C(OC(C)C)(=O)CCCCCCCCCCC
LogP: 6.234 (est)
EPA Substance Registry System: Dodecanoic acid, 1-methylethyl ester (10233-13-3)
Molecular Weight: 242.39700
Exact Mass: 242.40
EC Number: 233-560-1
UNII: U0JQ94LABM
DSSTox ID: DTXSID3041904
HScode: 2915900090
PSA: 26.30000
XLogP3: 4.85890
Appearance: colourless oily liquid

Density: 0.865 g/cm3
Boiling Point: 196 °C
Flash Point: 125ºC
Refractive Index: 1.436
Vapor Pressure: 0.00358mmHg at 25°C
Molecular Weight:242.40
XLogP3:6.1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:12
Exact Mass:242.224580195
Monoisotopic Mass:242.224580195
Topological Polar Surface Area:26.3
Heavy Atom Count:17
Complexity:176
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
IUPAC Name: Propan-2-yl tetradecanoate
Molecular Weight: 270.5

Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChI: InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI Key: AXISYYRBXTVTFY-UHFFFAOYSA-N
Boiling Point: 193 °C
Melting Point: 3 °C
Flash Point: >230 °F
Density: 0.85 g/mL at 25 °C(lit.)
Solubility: Water-insoluble, but soluble with silicones, and hydrocarbons
Appearance: Colorless oil-like liquid, odorless
Storage: Store in a closed container at a dry place at room temperature
Alpha Sort: Isopropyl myristate
Complexity: 199
Composition: Isopropyl myristate
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
EC Number: 203-751-4
Exact Mass: 270.255880323
Heavy Atom Count: 19

Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
MDL Number: MFCD00008982
Monoisotopic Mass: 270.255880323
Odor: Practically odorless
Packing Group: I; II; III
Physical State: Liquid
Refractive Index: n20/D 1.434(lit.)
Rotatable Bond Count: 14
Safty Description: S26-S36
Stability: Stable.
Topological Polar Surface Area: 26.3 Ų
Vapor Pressure: 0.000329mmHg at 25°C
Viscosity: 4.8cp (25°C)
Appearance: Liquid
Melting point: 4.2°C (estimate)
Boiling point: 285.23°C (estimate)
Density: 0.8536



FIRST AID MEASURES of ISOPROPYL LAURATE:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOPROPYL LAURATE:
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ISOPROPYL LAURATE:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL LAURATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Appropriate engineering controls:
General industrial hygiene practice.
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing.
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
No special environmental precautions required.



HANDLING and STORAGE of ISOPROPYL LAURATE:
-Conditions for safe storage, including any incompatibilities:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of ISOPROPYL LAURATE:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Isopropyl dodecanoate
ISOPROPYL LAURATE
10233-13-3
propan-2-yl dodecanoate
Dodecanoic acid, 1-methylethyl ester
1-Methylethyl dodecanoate
U0JQ94LABM
MFCD00451146
WE(2:0(1Me)/12:0)
UNII-U0JQ94LABM
Isopropyl_laurate
iso-Propyl dodecanoate
EINECS 233-560-1
SCHEMBL44513
Isopropyl laurate, AldrichCPR
LEXOL IPL
DUB LAIP
EC 233-560-1
AEC ISOPROPYL LAURATE
dodecanoic acid isopropyl ester
DTXSID3041904
ISOPROPYL LAURATE [INCI]
CHEBI:89676
Dodecanoic acid methylethyl ester
UJPPXNXOEVDSRW-UHFFFAOYSA-N
LMFA07010674
AKOS014763161
CS-W002613
DS-2780
SY003934
FT-0696522
Q5971737
W-108876
(+)-TRANS-1,2-CYCLOHEXANEDICARBOXYLICANHYDRIDE
56S
ISOPROPYL LAURATE
1-Methylethyldodecanoate
Dodecanoic acid, 1-methylethyl ester
Dodecanoicacid,1-methylethylester
dodecanoicacidisopropylester
isopropyl
isopropyl dodecanoate
Dodecansyre, 1-methyl-ethyl-ester
1-METHYLETHYL DODECANOATE
AEC ISOPROPYL LAURATE
DODECANOIC ACID, 1-METHYLETHYL ESTER
DUB LAIP
ISOPROPYL DODECANOATE
ISOPROPYL LAURATE
ISOPROPYL LAURATE [INCI]
LEXOL IPL
Dodecanoic acid, 1-methylethyl ester
Lauric acid,isopropyl ester
Emcol-IL
Isopropyl laurate
Isopropyl dodecanoate
Dodecanoic acid isopropyl ester
1-Methylethyl dodecanoate
Loxanol MI 6460
Dodecanoic acid, 1-methylethyl ester
1-Methylethyl dodecanoate
iso-Propyl dodecanoate
propan-2-yl dodecanoate
1-Methylethyl dodecanoate
ISOPROPYL LAURATE
dodecanoicacidisopropylester
Dodecanoic acid, 1-methylethyl ester
Dodecanoicacid,1-methylethylester
Dodecanoic acid methylethyl ester
isopropyl
1-Methylethyldodecanoate
Dodecansyre, 1-methyl-ethyl-ester
Isopropyl dodecanoate



ISOPROPYL LINOLEATE
ISOPROPYL MYRISTATE; Tetradecanoic acid 1-methylethyl ester; Estergel; Myristic Acid, Isopropyl Ester; Bisomel; Tegester; Tetradecanoic Acid, Isopropyl; cas no: 110-27-0; 1405-98-7
ISOPROPYL MYRISTATE
ISOPROPYL MYRISTATE = IPM

Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
Isopropyl myristate mainly works as an emollient in cosmetics and personal care products.
Isopropyl myristate has an oily base with low viscosity and adapts well to the skin.

CAS number: 110-27-0
EC number: 203-751-4
Chemical Formula: C17H34O2
Molar Mass: 270.45 g/mol

Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.

Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.

Isopropyl myristate is a natural product found in Siraitia grosvenorii, Mangifera indica, and other organisms with data available.
Isopropyl tetradecanoate is a fatty acid ester.

Isopropyl Myristate is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Isopropyl myristate is a clear, colorless oil-like liquid that makes the skin feel smooth and nice (aka emollient) and Isopropyl Myristate does so without being greasy.

What's more, Isopropyl Myristate can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl Myristate's also fast-spreading meaning that Isopropyl Myristate gives the formula a good, nice slip.
Isopropyl Myristate absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper.

Isopropyl myristate is a texture enhancer and emollient as used in cosmetics.
There is also research showing Isopropyl Myristate can help enhance the absorption of ingredients in a cosmetic formula.

Isopropyl myristate is often called out as being a particularly bad pore-clogging ingredient.
However, this assessment comes from dated research that doesn’t apply to how this ingredient is used in today’s cosmetics.

Isopropyl Myristate is a synthetic oil used as an emollient, thickening agent and lubricant in beauty and personal care products.
Isopropyl Myristate is composed of of Isopropyl Alcohol (a propane derivative) and Myristic Acid (a naturally-occurring fatty acid), Isopropyl Myristate is most often used an an additive in aftershaves, shampoos, bath oils, antiperspirants, deodorants, oral hygiene products, and various creams and lotions.

A unique characteristic of Isopropyl Myristate is Isopropyl Myristate ability to reduce the greasy feel caused by the high oil content of other ingredients in a product.
This synthetic oil is often added to beauty products to give them a slicker, sheer feel rather than an oily one.

Isopropyl Myristate is an emollient ester of low viscosity; the product of the reaction of isopropanol with myristic acid (vegetable source).
A non-greasy emollient, Isopropyl Myristate is readily adsorbed by the skin.

Miscible with most oils, Isopropyl Myristate imparts a dry, velvety emollience to products.
Isopropyl Myristate is used to reduce the greasiness of lotion bars, whipped butters and emulsions.

Isopropyl Myristate is resistant to oxidation and will not become rancid.
Isopropyl Myristate is also an effective diluent for fragrance oils.

Isopropyl myristate is an oily, clear, colorless, soluble liquid alcohol, oils, petrolatum and glycerine, insoluble in water.
Isopropyl Myristate is obtained by reacting myristic acid with isopropanol.

Isopropyl Myristate is an excellent vehicle because resistant to oxidation, Isopropyl Myristate is not rancid, also is not irritating or sensitizing and is rapidly absorbed by the skin without leaving any residue

Isopropyl Myristate has an emollient, moisturizing and protective action of the skin.
Isopropyl Myristate is incorporated in the fatty phase of the emulsions to enhance Isopropyl Myristate cosmetic appearance and enhance penetration of active ingredients.

Isopropyl myristate is a traditional, fast spreading emollient for modern cosmetic applications.
Isopropyl Myristate is a clear, colorless, almost odorless oil of medium polarity with a mean molecular weight, and a spreading value of approx. 1200 mm²/10 min.
Isopropyl Myristate has a saponification value of 205-211, a refractive index (20°C) of 1.4335-1.4355, and a density (20°C) of 0.850 – 0.855g/cm³.

Isopropyl Myristate is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.
Isopropyl Myristate is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Applications of Isopropyl Myristate:
Isopropyl myristate is a texture enhancer and emollient as used in cosmetics.
Isopropyl Myristate can also help to enhance the absorption of ingredients in a cosmetic formula.

Skin care:
Isopropyl Myristate works as an emollient, thickener, and a lubricant in beauty products.
Isopropyl Myristate locks in the hydration, and enhances the penetration of other ingredients in the formulation.

Isopropyl myristate is an effective agent for solubilizing lanolin.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content.

Isopropyl Myristate leaves the skin soft and smooth without an oily surface film.
Isopropyl Myristate can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl Myristate's also fast-spreading meaning that Isopropyl Myristate gives the formula a good, nice slip

Hair care:
Isopropyl Myristate works as a hydrating agent, emollient, and enhancer.
Isopropyl Myristate hydrates the hair and the scalp and enhances the penetration of other ingredients in the formulation.
Isopropyl Myristate is not recommended for particularly thin hair, as Isopropyl Myristate can make it appear greasy, or an oily scalp or hair, as Isopropyl Myristate can lead to clogged pores.

Other Applications:
After Sun
Antiperspirants & Deodorants
Baby Care and Cleansing
Body Care
Color Care
Conditioning
Face Care
Face Cleansing
Personal Care Wipes
Self Tanning
Sun Protection

Uses of Isopropyl Myristate:
Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Isopropyl Myristate is also used as a treatment for head lice.
Isopropyl Myristate is also in flea and tick killing products for pets.

Isopropyl Myristate is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.

Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol.
The acid is theorized to be responsible for decreasing of the pH value of formulations.

Isopropyl Myristate is used as emollient and emulsifier in cosmetics and topical medicines, parenteral solvent (intravenous solutions), and reagent in tests for sterility.
Isopropyl Myristate is used in cosmetic and topical medicinal preparations.

Isopropyl myristate is an effective agent for solubilizing lanolin; mixtures of up to about 50% lanolin in isopropyl myristate remain stable, free-flowing liquid at room temperature.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content.

Isopropyl myristate leaves the skin soft and smooth without an oily surface film.
Isopropyl Myristate is used in bath oils, perfumes, creams lotions, lipsticks, hair preparations, shaving lotions, aerosol toiletries, and pharmaceutical ointments.

Widespread uses by professional workers:
Isopropyl Myristate is used in the following products: washing & cleaning products and polishes and waxes.
Isopropyl Myristate is used in the following areas: formulation of mixtures and/or re-packaging.

Isopropyl Myristate is used for the manufacture of: chemicals and .
Other release to the environment of Isopropyl Myristate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Uses at industrial sites:
Isopropyl Myristate is used in the following products: washing & cleaning products, metal surface treatment products and lubricants and greases.
Isopropyl Myristate is used in the following areas: formulation of mixtures and/or re-packaging.

Isopropyl Myristate is used for the manufacture of: chemicals and .
Release to the environment of Isopropyl Myristate can occur from industrial use: in processing aids at industrial sites and in the production of articles.

Industry Uses:
Defoamer
Diluent
Fragrance
Intermediate
Odor agents
Process regulators

Consumer Uses:
Isopropyl Myristate is used in the following products: washing & cleaning products, lubricants and greases, textile treatment products and dyes, adhesives and sealants, polymers and polishes and waxes.
Release to the environment of Isopropyl Myristate can occur from industrial use: in the production of articles.
Other release to the environment of Isopropyl Myristate is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

Other Consumer Uses:
Fragrance
Odor agents
Process regulators

Therapeutic Uses of Isopropyl Myristate:
Isopropyl myristate 50% in cyclomethicone solution is a new fluid treatment with a physical mode of action that uses a 10-minute contact time /for treatment of head lice.

A pediculicide rinse, 50% isopropyl myristate (IPM), was assessed in two phase 2 trials conducted in North America.
The first trial was a nonrandomized (proof of concept) trial without a comparator conducted in Winnipeg, Canada.

The second trial, conducted in the United States, was an evaluator-blinded, randomized superiority trial comparing 50% Isopropyl Myristate rinse with a positive control (RID; pyrethrin 0.33%, piperonyl butoxide 4%).
The primary end points were to determine the safety and efficacy of 50% Isopropyl Myristate as a pediculicide rinse.

METHODS:
Subjects meeting inclusion criteria were enrolled in the above-mentioned trials with efficacy end points 7 and 14 days post-treatment.
Subjects were also evaluated on days 0, 7, 14, and 21 for the presence of erythema and edema using the Modified Draize Scale.
Other comments associated with the safety evaluation (ie, pruritus) were collected.

RESULTS:
Isopropyl Myristate was found to be effective in the proof of concept study and comparator trial using a positive control.
Isopropyl Myristate was also well tolerated, with minimal adverse events.
All adverse events were mild, resolving by completion of the study.

CONCLUSION:
Data suggest that Isopropyl Myristate is a safe and effective therapy for the treatment of head lice in children and adults.
Isopropyl Myristate's mechanical mechanism of action makes development of lice resistance unlikely.

Drug Indication of Isopropyl Myristate:
The primary medical indication for which isopropyl myristate is formally used as an active ingredient in a patient care product is as a non-prescription pediculicide rinse.

Pharmacology and Biochemistry of Isopropyl Myristate:

Pharmacodynamics:
Isopropyl myristate is an emollient vehicle that is effective at enhancing the penetration of other medical agents that may be incorporated into the vehicle as active agents.
In one study, a 50:50 isopropanol-isopropyl myristate binary enhancer synergistically increased the transport of estradiol across a two-layer human epidermis in vitro.

Absorption, Distribution and Excretion of Isopropyl Myristate:

Absorption:
Dermal absorption of isopropyl myristate is predicated to be 0.00020 mg/cm2/event, which is considered a very low absorption rate.
In a study, topically applied isopropyl myristate was largely retained in the stratum corneum.
Isopropyl Myristate was not detected in the receptor fluid of flow-through diffusion cells in in-vitro skin permeation experiments using human epidermis (stratum corneum and viable epidermis) and dermis of varying thickness.

Action Mechanism of Isopropyl Myristate:
As a pediculicide, isopropyl myristate is capable of physically coating the exoskeleton bodies of lice.
This physical coating subsequently immobilizes the lice and works to dissolve the wax covering on the insect exoskeleton and blocks the insects' airways, leading to death by dehydration.

Although this physical action of isopropyl myristate results in little lice resistance (given the lack of immunologic or chemical activity in this mechanism of action), Isopropyl Myristate is also not ovicidal, which means any eggs that may have been laid by lice would not be affected.
Moreover, isopropyl myristate is capable of eliciting Isopropyl Myristate pediculicide action in a contact time of only 10 minutes per each necessary administration.

Human Metabolite Information of Isopropyl Myristate:

Cellular Locations:
Extracellular
Membrane

Manufacturing Methods of Isopropyl Myristate:
Isopropyl myristate is commercially produced by distillation, which is preceded by the esterification of myristic acid and isopropanol, alkali refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.

General Manufacturing Information of Isopropyl Myristate:

Industry Processing Sectors:
All Other Chemical Product and Preparation Manufacturing
Asphalt Paving, Roofing, and Coating Materials Manufacturing
Not Known or Reasonably Ascertainable
Other (requires additional information)
Pesticide, Fertilizer, and Other Agricultural Chemical Manufacturing
Petrochemical Manufacturing
Plastics Material and Resin Manufacturing
Printing and Related Support Activities
Soap, Cleaning Compound, and Toilet Preparation Manufacturing

Accidental Release Measures of Isopropyl Myristate:

Disposal Methods:
Criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision.
Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Identifiers of Isopropyl Myristate:
CAS Number: 110-27-0
ChEMBL: ChEMBL207602
ChemSpider: 7751
ECHA InfoCard: 100.003.412
EC Number: 203-751-4
KEGG: D02296
MeSH: C008205
PubChem CID: 8042
RTECS number: XB8600000
UNII: 0RE8K4LNJS
CompTox Dashboard (EPA): DTXSID0026838
InChI:
InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
Key: AXISYYRBXTVTFY-UHFFFAOYSA-N
InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
Key: AXISYYRBXTVTFY-UHFFFAOYAN
SMILES: CCCCCCCCCCCCCC(=O)OC(C)C

EC / List no.: 203-751-4
CAS no.: 110-27-0
Mol. formula: C17H34O2

CAS number: 110-27-0
EC number: 203-751-4
Hill Formula: C₁₇H₃₄O₂
Molar Mass: 270.45 g/mol
Quality Level: MQ300

CAS Number: 110-27-0
Chem/IUPAC Name: Tetradecanoic acid, isopropyl ester
EINECS/ELINCS No: 203-751-4
COSING REF No: 34699

Synonym(s): Isopropyl myristate, Tetradecanoic acid isopropyl ester, Myristic acid isopropyl ester
Empirical Formula (Hill Notation): C17H34O2
CAS Number: 110-27-0
Molecular Weight: 270.45
MDL number: MFCD00008982
EC Index Number: 203-751-4

CAS: 110-27-0
Molecular Formula: C17H34O2
Molecular Weight (g/mol): 270.45
MDL Number: MFCD00008982
InChI Key: AXISYYRBXTVTFY-UHFFFAOYSA-N
PubChem CID: 8042
IUPAC Name: propan-2-yl tetradecanoate
SMILES: CCCCCCCCCCCCCC(=O)OC(C)C

Properties of Isopropyl Myristate:
Chemical formula: C17H34O2
Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg

Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility:
Quality Level: 500
Vapor pressure: Form: liquid
Autoignition temp.: >300 °C
bp: 140 °C/3 hPa
Transition temp: flash point >150 °C
Density: 0.85 g/cm3 at 20 °C
Storage temp.: 15-25°C
InChI: 1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChI key: AXISYYRBXTVTFY-UHFFFAOYSA-N

Molecular Weight: 270.5
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323
Monoisotopic Mass: 270.255880323
Topological Polar Surface Area: 26.3 Ų
Heavy Atom Count: 19
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Isopropyl Myristate:
Color according to color reference solution Ph.Eur.: colorless liquid
Assay (GC, area%): ≥ 98.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.853 - 0.854
Identity (IR): passes test

Acidity: 0.5mg KOH/g max.
Density: 0.8500g/mL
Boiling Point: 167.0°C (9.0 mmHg)
Flash Point: >110°C
Assay Percent Range: 95% min. (GC)
Infrared Spectrum: Authentic
Linear Formula: CH3(CH2)12COOCH(CH3)2
Packaging: Glass bottle
Merck Index: 15, 5261
Refractive Index: 1.4340 to 1.4360
Quantity: 25 g
Specific Gravity: 0.85
Formula Weight: 270.45
Percent Purity: 96%
Physical Form: Liquid
Chemical Name or Material: Isopropyl myristate, 96%

Acid Value (mg KOH/g): 0.5 Max
Saponification Value (mg KOH/g): 206-211
Color (APHA): 30 Max
Moisture Content (%): 0.1 Max
Ash Content (%): 0.1 Max
Peroxide Value (meq/Kg): 0.6 Max
Viscosity (mPa.s) 20℃: 5-6
Density (g/cm3) 20℃: 0.852-0.855
Refractive Index 20℃: 1.434-1.437

Names of Isopropyl Myristate:

Regulatory process names:
Isopropyl myristate
isopropyl myristate

CAS names:
Tetradecanoic acid, 1-methylethyl ester

IUPAC names:
1-Methylethyl Tetradecanoate
Alkyl alkanoate
bisomel
cadmium
IPM
ISOPROPYL MYRISTATE
Isopropyl Myristate
Isopropyl myristate
isopropyl myristate
ISOPROPYL MYRISTATE
Isopropyl Myristate
Isopropyl myristate
isopropyl myristate
Isopropyl Myristate (Tetradecanoic acid, 1-methylethyl ester) CAS 110-27-0
Isopropylmyristat
isopropylmyristate
Isopropylmyristate
Propan-2-yl tetradecanoate
propan-2-yl tetradecanoate
Tetradecanoic acid, 1-methylethyl ester
TETRADECANOIC ACID, 1-METHYLETHYL ESTER( MAIN COMPONENT )
Tetradecanoic acid, isopropyl ester
Tetradecanoic acid, isopropylester
Tetradecansäure-1-methylethylester

Preferred IUPAC name:
Propan-2-yl tetradecanoate

Trade names:
CHINT: FCE (i-Propyl)E C14
Crodamol IPM
DUB IPM
IPM-S
Isopropyl Palmitate
MMEster E1140
PALMESTER
Palmsurf IPM
Phase I REACH Kandidat
Q-Cos Oleo IPM
RADIA 7191
RADIA 7727
RADIA 7730
RADIA 7730K
RADIA 7730Q
WAGLINOL 6014
WAGLINOL 6014/95
WAGLINOL 6014/98
WAGLINOL 6014/N

Other names:
Tetradecanoic acid
1-methylethyl ester
Myristic acid isopropyl ester

Synonyms of Isopropyl Myristate:
ISOPROPYL MYRISTATE
110-27-0
Isopropyl tetradecanoate
Tetradecanoic acid, 1-methylethyl ester
Estergel
Bisomel
Isomyst
Promyr
Deltyl Extra
propan-2-yl tetradecanoate
Kesscomir
Tegester
Wickenol 101
Sinnoester MIP
Crodamol IPM
Plymoutm IPM
Stepan D-50
Starfol IPM
Unimate IPM
Kessco IPM
Emcol-IM
Myristic acid isopropyl ester
Emerest 2314
1-Methylethyl tetradecanoate
JA-FA IPM
FEMA No. 3556
Kessco isopropyl myristate
Crodamol I.P.M.
Tetradecanoic acid, isopropyl
Myristic acid, isopropyl ester
Isopropyl myristate [USAN]
Tetradecanoic acid, isopropyl ester
HSDB 626
NSC 406280
1-Tridecanecarboxylic acid, isopropyl ester
Estergel (TN)
methylethyl tetradecanoate
0RE8K4LNJS
iso-Propyl N-tetradecanoate
NSC-406280
CHEBI:90027
Tetradecanoic acid methyethyl ester
1405-98-7
NCGC00164071-01
Deltylextra
WE(2:0(1Me)/14:0)
Isopropyl myristate, 98%
Caswell No. 511E
CAS-110-27-0
EINECS 203-751-4
UNII-0RE8K4LNJS
MFCD00008982
EPA Pesticide Chemical Code 000207
Isopropyl tetradecanoic acid
BRN 1781127
Tegosoft M
Isopropyl myristate [USAN:NF]
Liponate IPM
Crodamol 1PM
isopropyl-myristate
Lexol IPM
Isopropyltetradecanoate
myristic acid isopropyl
Radia 7190
Isopropyl myristate (NF)
EC 203-751-4
SCHEMBL2442
Myristic acid-isopropyl ester
Isopropyl myristate, >=98%
CHEMBL207602
IPM 90
DTXSID0026838
ISOPROPYL MYRISTATE [II]
ISOPROPYL MYRISTATE [MI]
WLN: 13VOY1&1
FEMA 3556
tetradecanoic acid isopropyl ester
ISOPROPYL MYRISTATE [FHFI]
ISOPROPYL MYRISTATE [HSDB]
ISOPROPYL MYRISTATE [INCI]
ISOPROPYL MYRISTATE [VANDF]
ISOPROPYL MYRISTATE [MART.]
ZINC8214588
Isopropyl myristate, >=90% (GC)
Tox21_112080
Tox21_202065
Tox21_303171
ISOPROPYL MYRISTATE [USP-RS]
ISOPROPYL MYRISTATE [WHO-DD]
LMFA07010677
NSC406280
s2428
AKOS015902296
Tox21_112080_1
DB13966
NCGC00164071-02
NCGC00164071-03
NCGC00256937-01
NCGC00259614-01
ISOPROPYL MYRISTATE [EP MONOGRAPH]
LS-14615
DB-040910
HY-124190
CS-0085813
FT-0629053
M0481
MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER
D02296
F71211
TETRADECONOIC ACID, 1-METHYLETHYL ESTER
EN300-25299830
Q416222
SR-01000944751
Isopropyl myristate, Vetec(TM) reagent grade, 98%
Q-201418
SR-01000944751-1
Isopropyl myristate, United States Pharmacopeia (USP) Reference Standard
TETRADECANOIC ACID,ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER)
Isopropyl myristate, Pharmaceutical Secondary Standard; Certified Reference Material
Lexate® TA
Lexol® 3975
Lexol® IPM
Lexol® IPM-NF MB
PALMESTER 1512 Isopropyl Myristate
PALMESTER 1514 Isopropyl Myristate
PARYOL EMOLL
PARYOL IPM
AE Ester IPM
Polymol® IPM
Dermol IPM
Wickenol 101
BergaCare EM-14
BergaCare EM-14 /MB
MIRITOL™ PM
CremerCOOR® IPM
Isopropyl Myristate 98%
MASSOCARE IPM
MASSOCARE SWAN
Crodarom® Carrot O (D)
Estol 1514 (D)
Spectraveil™ IPM (D)
Carrot Oil Extra
Crodamol™ CAP
DomusCare® IPM
Bentone Gel® IPM V
ERCAREL IPM V
TEGOSOFT® Liquid M
TEGOSOFT® M
Georges Walther ISOPROPYL MYRISTATE
Unipherol U-14
GranLux® IM1-40
CoVera™ IPM
HallStar® IPM
Dapracare® IPM
Aloe Vera Oil Extract IPM base
Jeelux® DMIPM
Jeelux® VHIPP
Exceparl® HO (D)
Dp-VitAHP2k (D)
IPM55S4 (D)
GCB50YSG
0RE8K4LNJS
110-27-0 [RN]
13VOY1&1 [WLN]
1-Methylethyl tetradecanoate
203-751-4 [EINECS]
IPM
IPM 100
IPM-EX
IPM-R
Isopropyl myristate [ACD/IUPAC Name] [USAN]
isopropyl tetradecanoate
Isopropylmyristat [German] [ACD/IUPAC Name]
MFCD00008982 [MDL number]
Myristate d'isopropyle [French] [ACD/IUPAC Name]
myristic acid isopropyl ester
Myristic acid, isopropyl ester
Propan-2-yl tetradecanoate
Tetradecanoic acid 1-methylethyl ester
Tetradecanoic acid isopropyl ester
Tetradecanoic acid, 1-methylethyl ester [ACD/Index Name]
Tetradecanoic acid, isopropyl ester
XB8600000
1-Tridecanecarboxylic acid, isopropyl ester
4-02-00-01132 (Beilstein Handbook Reference) [Beilstein]
Bisomel
Crodamol 1PM
Crodamol IPM
DELTYL EXTRA
Deltylextra
EINECS 203-751-4
Emcol-IM
Emerest 2314
Estergel [Trade name]
Estergel (TN)
FEMA 3556
IPM 90
Isomyst
Isopropyl myristate (NF)
iso-Propyl N-tetradecanoate
Isopropyl tetradecanoic acid
Isopropylmyristate
Isopropylmyristate, Tetradecanoic acid isopropyl ester, Myristic acid isopropyl ester, Sterile IPM
Ja-fa IPM
Jsp000796
Kessco IPM
Kessco isopropyl myristate
Kesscomir
Lexol IPM
Liponate IPM
Methylethyl tetradecanoate
Myristic acid-isopropyl ester
NCGC00164071-01
Promyr
Radia 7190
Sinnoester MIP
Starfol IPM
Stepan D-50
Sterile Isopropyl Myristate (IPM)
Tegester
Tegosoft M
Tetradecanoic acid isopropyl ester, Myristic acid isopropyl ester
Tetradecanoic acid methyethyl ester
Tetradecanoic acid, isopropyl
UNII:0RE8K4LNJS
UNII-0RE8K4LNJS
Unimate IPM
WE(2:0(1Me)/14:0)
Wickenol 101
WLN: 13VOY1&1
ISOPROPYL MYRISTATE
DESCRIPTION:
Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.

CAS: 110-27-0
European Community (EC) Number: 203-751-4
IUPAC Name: propan-2-yl tetradecanoate


Isopropyl myristate is a natural product found in Siraitia grosvenorii, Mangifera indica, and other organisms with data available.
Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.

A synthetic oil, isopropyl myristate is made up of isopropyl alcohol—a propane derivative—and myristic acid, a naturally-occurring fatty acid, explains Palep.
While it's not necessarily a solo skincare star that you'll find touted as a hero ingredient, it's a popular cosmetic ingredient in a wide array of beauty products, found in everything from aftershave to anti-perspirants to anti-aging creams.

"By thickening formulas, it gives products a denser texture and also improves the overall texture of those with a high oil content to be silky rather than greasy," says Palep.
And while that's a major win for the labs and scientists making your beauty products, it does have skincare benefits for you, too.
While there are plenty of emollients on the market, isopropyl myristate has the added benefit of enhancing the penetration of other ingredients.


A clear, colorless oil-like liquid that makes the skin feel smooth and nice (aka emollient) and Isopropyl myristate does so without it being greasy.
What's more, Isopropyl myristate can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl myristate is also fast-spreading meaning that it gives the formula a good, nice slip.
Isopropyl myristate absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper

Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
Isopropyl myristate mainly works as an emollient in cosmetics and personal care products.
Isopropyl myristate has an oily base with low viscosity and adapts well to the skin.

Isopropyl myristate is an ester of isopropyl alcohol and myristic acid.
Isopropyl myristate is used as a softener in cosmetic products and as a solvent in perfumes.
IPM is widely used in products against head lice and in flea and tick killing products for pets.

You can find Isopropyl myristate most often in aftershave products, shampoos, bath oils, antiperspirants and deodorants, mouthwash products, in various body milks and facial creams.
Its unique ability is to reduce oily feeling on the skin caused by a high content of oil.
Isopropyl myristate is easily absorbed by the skin and ensures quick penetration of product substances into the skin.

Isopropyl myristate is insoluble in water.
At concentration above 5% it might clog pores (it’s comedogenic).

Isopropyl myristate is the Ester of isopropyl alcohol and myristic acid (vegetable-derived).
Isopropyl myristate is Low viscosity fluid non-greasy emollient, tolerates wide pH range, compatible with most surfactants.
Thanks to its low viscosity and density, Isopropyl myristate has a high spreadability.
Isopropyl myristate has Specific gravity of 0.85 (at 20°C).

USES OF ISOPROPYL MYRISTATE:
Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Isopropyl myristate is also used as a treatment for head lice.
Isopropyl myristate is also in flea and tick killing products for pets.

Isopropyl myristate is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.

Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol.
The acid is theorized to be responsible for decreasing of the pH value of formulations.


Isopropyl myristate is a texture enhancer and emollient as used in cosmetics.
Isopropyl myristate can also help to enhance the absorption of ingredients in a cosmetic formula.
Skin care:
Isopropyl myristate works as an emollient, thickener, and a lubricant in beauty products.
Isopropyl myristate locks in the hydration, and enhances the penetration of other ingredients in the formulation.
Isopropyl myristate is an effective agent for solubilizing lanolin.

Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content.
Isopropyl myristate leaves the skin soft and smooth without an oily surface film.

Isopropyl myristate can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl myristate is also fast-spreading meaning that it gives the formula a good, nice slip

Hair care:
Isopropyl myristate works as a hydrating agent, emollient, and enhancer.
Isopropyl myristate hydrates the hair and the scalp and enhances the penetration of other ingredients in the formulation.
Isopropyl myristate is not recommended for particularly thin hair, as Isopropyl myristate can make it appear greasy, or an oily scalp or hair, as it can lead to clogged pores



ORIGIN OF ISOPROPYL MYRISTATE:
Isopropyl myristate is commercially produced by distillation, before which the esterification of myristic acid and isopropanol is carried out, and the resulting alkali is refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.

WHAT DOES ISOPROPYL MYRISTATE DO IN A FORMULATION?
• Emollient
• Perfuming
• Skin conditioning
• Viscosity controlling




BENEFITS OF ISOPROPYL MYRISTATE FOR SKIN:
Softens the skin:
As an emollient, it helps soften and smooth dry skin, which is why this is a choice ingredient for those with dry or flaky skin.

Enhances the penetration of other ingredients:
According to Belkin, the exact mechanism by which this works isn't fully clear, but it's thought that isopropyl myristate changes the structure of the stratum corneum, the most external layer of the skin, making it easier for active ingredients to absorb.
In turn, this can make the skincare you're using more effective.

Improves product texture:
This benefit doesn't relate exactly to the skin, but isopropyl myristate can make skincare products have that lush, creamy, but not oily feel, according to Palep.


Isopropyl myristate is the Superior emollient for non-greasy bath, body and baby oils
Isopropyl myristate is Lubricant and compression aid for pressed powders
Isopropyl myristate is Light & non-tacky emollient for creams and lotions.
Isopropyl myristate is Readily adsorbed by the skin

When used at high concentrations Isopropyl myristate gently lifts makeup and surface dirt
Isopropyl myristate Gives gloss and shine to hair
Isopropyl myristate is Resistant to oxidation (does not become rancid)
Isopropyl myristate is Widely used as diluent for fragrance oils.


HOW TO USE ISOPROPYL MYRISTATE:
Because it's found in so many different products and formulations, your best bet is to follow the instructions on any particular product.
Still, you're likely to be limited more by the actives in a product than minor ingredients like isopropyl myristate, notes Belkin.

SAFETY INFORMATION ABOUT ISOPROPYL MYRISTATE:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product



CHEMICAL AND PHYSICAL PROPERTIES OF ISOPROPYL MYRISTATE:
Molecular Weight 270.5 g/mol
XLogP3-AA 7.2
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 14
Exact Mass 270.255880323 g/mol
Monoisotopic Mass 270.255880323 g/mol
Topological Polar Surface Area 26.3Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 199
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
Chemical formula C17H34O2
Molar mass 270.457 g•mol−1
Density 0.85 g/cm3
Boiling point 167 °C (333 °F; 440 K) at 9 mmHg
CAS number 110-27-0
EC number 203-751-4
Hill Formula C₁₇H₃₄O₂
Molar Mass 270.45 g/mol
Boiling point 140 °C (3 hPa)
Density 0.85 g/cm3 (20 °C)
Flash point >150 °C
Ignition temperature >300 °C
Vapor pressure Solubility Storage Store at +15°C to +25°C.







SYNONYMS OF ISOPROPYL MYRISTATE:

isopropyl myristate
isopropylmyristate
0RE8K4LNJS
1-Methylethyl tetradecanoate
1-Tridecanecarboxylic acid, isopropyl ester
110-27-0
1405-98-7
AKOS015902296
Bisomel
BRN 1781127
CAS-110-27-0
Caswell No. 511E
CHEBI:90027
CHEMBL207602
Crodamol 1PM
Crodamol I.P.M
Crodamol I.P.M.
Crodamol IPM
CS-0085813
D02296
DB13966
Deltyextra
Deltyl Extra
Deltylextra
DTXCID306838
DTXSID0026838
EC 203-751-4
EINECS 203-751-4
Emcol-IM
Emerest 2314
EN300-25299830
EPA Pesticide Chemical Code 000207
Estergel
Estergel (TN)
F71211
FEMA 3556
FEMA No. 3556
FT-0629053
HSDB 626
HY-124190
IPM 90
iso-Propyl N-tetradecanoate
Isomyst
isopropyl myristate
ISOPROPYL MYRISTATE
ISOPROPYL MYRISTATE (EP MONOGRAPH)
ISOPROPYL MYRISTATE (II)
ISOPROPYL MYRISTATE (MART.)
Isopropyl myristate (NF)
ISOPROPYL MYRISTATE (USP-RS)
ISOPROPYL MYRISTATE [EP MONOGRAPH]
ISOPROPYL MYRISTATE [FHFI]
ISOPROPYL MYRISTATE [HSDB]
ISOPROPYL MYRISTATE [II]
ISOPROPYL MYRISTATE [INCI]
ISOPROPYL MYRISTATE [MART.]
ISOPROPYL MYRISTATE [MI]
Isopropyl myristate [USAN:NF]
Isopropyl myristate [USAN]
ISOPROPYL MYRISTATE [USP-RS]
ISOPROPYL MYRISTATE [VANDF]
ISOPROPYL MYRISTATE [WHO-DD]
Isopropyl myristate, >=90% (GC)
Isopropyl myristate, >=98%
Isopropyl myristate, 98%
Isopropyl myristate, Pharmaceutical Secondary Standard; Certified Reference Material
Isopropyl myristate, United States Pharmacopeia (USP) Reference Standard
Isopropyl myristate, Vetec(TM) reagent grade, 98%
Isopropyl tetradecanoate
Isopropyl tetradecanoic acid
isopropyl-myristate
Isopropyltetradecanoate
JA-FA IPM
Kessco IPM
Kessco isopropyl myristate
Kesscomir
Lexol IPM
Liponate IPM
LMFA07010677
LS-2869
M0481
methylethyl tetradecanoate
MFCD00008982
MYRISTATE, ISOPROPYL
myristic acid isopropyl
Myristic acid isopropyl ester
MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER
Myristic acid, isopropyl ester
Myristic acid, isopropyl ester; (Tetradecanoic acid, isopropyl; Isopropyl myristate)
Myristic acid-isopropyl ester
NCGC00164071-01
NCGC00164071-02
NCGC00164071-03
NCGC00256937-01
NCGC00259614-01
NSC 406280
NSC-406280
NSC406280
Plymoutm IPM
Promyr
propan-2-yl tetradecanoate
Q-201418
Q416222
Radia 7190
s2428
SCHEMBL2442
Sinnoester MIP
SR-01000944751
SR-01000944751-1
Starfol IPM
Stepan D-50
Tegester
Tegosoft M
tetradecanoic acid 1-methylethyl ester
tetradecanoic acid isopropyl ester
Tetradecanoic acid methyethyl ester
Tetradecanoic acid, 1-methylethyl ester
Tetradecanoic acid, isopropyl
Tetradecanoic acid, isopropyl ester
TETRADECANOIC ACID,ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER)
TETRADECONOIC ACID, 1-METHYLETHYL ESTER
Tox21_112080
Tox21_112080_1
Tox21_202065
Tox21_303171
UNII-0RE8K4LNJS
Unimate IPM
USEPA/OPP Pesticide Code: 000207
WE(2:0(1Me)/14:0)
Wickenol 101
WLN: 13VOY1&1


ISOPROPYL MYRISTATE
Isopropyl Myristate is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Isopropyl tetradecanoate is a fatty acid ester.


CAS Number: 110-27-0
EC Number: 203-751-4
MDL number: MFCD00008982
Linear Formula: CH3(CH2)12COOCH(CH3)2
Molecular Formula: C17H34O2


Isopropyl Myristate is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Isopropyl myristate is a natural product found in Siraitia grosvenorii, Mangifera indica, and other organisms with data available.
Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.


Isopropyl Myristate is a clear, colorless oil-like liquid that makes the skin feel smooth and nice (aka emollient) and it does so without it being greasy.
Isopropyl myristate is commercially produced by distillation, before which the esterification of myristic acid and isopropanol is carried out, and the resulting alkali is refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.


What's more, Isopropyl Myristate can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl Myristate's also fast-spreading meaning that it gives the formula a good, nice slip.
Isopropyl Myristate absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper.


Hydrolysis of the ester from isopropyl myristate can liberate the acid and the alcohol.
Isopropyl Myristate is theorized to be responsible for decreasing of the pH value of formulations.
A synthetic oil, isopropyl myristate is made up of isopropyl alcohol—a propane derivative—and myristic acid, a naturally-occurring fatty acid.


While it's not necessarily a solo skincare star that you'll find touted as a hero ingredient, Isopropyl Myristate's a popular cosmetic ingredient in a wide array of beauty products, found in everything from aftershave to anti-perspirants to anti-aging creams.
You've most likely heard of moisture-enabling ingredients glycerin and hyaluronic acid, but we're willing to bet you've never heard of isopropyl myristate.


Though, if you were to do a quick scan of the skincare and personal care products currently in your bathroom, we're also willing to bet that Isopropyl Myristates in a large percentage of them.
An emollient ingredient, isopropyl myristate helps to ensure that moisture stays locked in.


But, unlike other emollients, the benefits don't stop there. Isopropyl myristate is unique in that it's able to enhance the penetration of other ingredients, not to mention it's essential when it comes to formulating and creating products that are cosmetically elegant.
Isopropyl myristate is one of only five ingredients in this serum.


Isopropyl Myristate promises to boost the efficacy of the star of the show: 15 percent of a stabilized version of skin-brightening vitamin C.
Top tip: Allow Isopropyl Myristate to soak into skin for five to 10 minutes, transforming from an oily to dry feeling, before layering any other products on top.


Isopropyl Myristateis a non-branched saturated fatty acid ester obtained from isopropanol and myristic acid, from palm oil.
Isopropyl Myristate is a clear liquid with a melting point of -3 ºC.
Isopropyl Myristate is fatty acid ester of isopropyl alcohol and myristic acid.


Isopropyl Myristate is an ester of isopropyl alcohol (aka rubbing alcohol) and myristic acid (a fatty acid that naturally occurs in coconut and palm oils).
Isopropyl Myristate is insoluble in glycerine and water.
Isopropyl Myristate is soluble in alcohol.


Isopropyl myristate is an ester of isopropanol and myristic acid.
Isopropyl Myristate is also referred to as tetradecanoic acid.
Isopropyl Myristate is an emollient.


Isopropyl Myristate is an oil component with low fatty character and high spreadability.
Isopropyl Myristate is an ester of isopropyl alcohol and myristic acid (vegetable-derived).
Isopropyl Myristate has low viscosity fluid non-greasy emollient, tolerates a wide pH range, compatible with most surfactants.


Thanks to its low viscosity and density, Isopropyl Myristate has a high spreadability.
Specific gravity of Isopropyl Myristate is 0.85 (at 20°C).
Isopropyl myristate is the synthetic oil widely used in the cosmetics as a lubricant and emollient.


Isopropyl Myristate is manufactured by condensing myristic acid with isopropyl alcohol.
Isopropyl myristate is readily absorbed by the skin and lessens the greasy nature of cosmetics while lending them a sheer, slick feel.
Generally Isopropyl myristate is considered to be safe.


Also known as IPM, Isopropyl Myristate is an all-natural ester derived from vegetable origin.
Isopropyl Myristate is an oil that can be used as a make-up remover and lubricant.
Isopropyl Myristate is an oil based remover that is incredibly gentle on the skin.


Isopropyl Myristate is good for removing regular make-up, grease paint and PAX or Pros-Aide.
Isopropyl Myristate is a compound derived from isopropyl alcohol and myristic acid.



USES and APPLICATIONS of ISOPROPYL MYRISTATE:
Isopropyl Myristate is used in personal care products to enhance their moisturising and skin conditioning properties.
Clean organoleptic quality make Isopropyl Myristate suitable for use as solvent for fragrance.
Isopropyl Myristate is a texture enhancer and emollient as used in cosmetics.


There is also research showing Isopropyl Myristate can help enhance the absorption of ingredients in a cosmetic formula.
Isopropyl myristate is often called out as being a particularly bad pore-clogging ingredient; however, this assessment comes from dated research that doesn’t apply to how this ingredient is used in today’s cosmetics.


Cosmetic formulations of Isopropyl Myristate: binding, fragrance, perfuming, emollient
Industrial uses of Isopropyl Myristate: manufacturer of washing and cleaning products, lubricants and greases, textile treatment products and dyes, polymers, adhesives, sealants, polishes and waxes.


Isopropyl Myristate made from the combination of isopropyl alcohol and the naturally derived fatty acid myristic acid.
Isopropyl Myristate helps gives a silky smooth and velvet texture when making cosmetics such as personal skin care products.
Isopropyl Myristate is used Cosmetic Grade for Soap Making, Fragrances, Shampoo, Creams & Lotion, Makeup & Adhesive Remover, Antiperspirants & Deodorants.


Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.


Isopropyl myristate is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Isopropyl Myristate is also used as a treatment for head lice.
Isopropyl Myristate is also in flea and tick killing products for pets.


Isopropyl Myristate is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl myristate is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.
Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.


Isopropyl Myristate mainly works as an emollient in cosmetics and personal care products.
Isopropyl Myristate has an oily base with low viscosity and adapts well to the skin.
Isopropyl myristate is a texture enhancer and emollient as used in cosmetics.


Isopropyl Myristate can also help to enhance the absorption of ingredients in a cosmetic formula.
Thanks to all this, Isopropyl Myristate's one of the most commonly used emollients out there.
There is just one little drawback: Isopropyl Myristate has a high comedogenic index (5 out of 5...), so it might clog pores if you're prone to it.


Isopropyl Myristate is used as an emulsifier and moisturizer for cosmetics.
Isopropyl Myristate has excellent effects of penetration, moisturizing and softening on skin.
Isopropyl Myristate is an important additive for high-grade cosmetics.


Isopropyl Myristate has excellent effects of penetration, moisturizing and softening on skin
Isopropyl Myristate is used as an emulsifier and moisturizer for cosmetics.
For ultra-dry or compromised skin (think post-procedure or when you're dealing with flaking and cracking), this healing balm is a prime choice.


Emollients such as squalane—and, you guessed it, isopropyl myristate—are meant to hydrate and soften skin, while petrolatum, an occlusive ingredient, seals in moisture.
Made with coconut, sweet almond, and sunflower seed oils, this body hydrator packs a nice hit of moisture, and isopropyl myristate promises to keep the formula from ever feeling greasy, leaving skin silky and soft.


While Isopropyl Myristate contains no artificial or added fragrance (a win for those with sensitive skin), it does contain ylang ylang oil, which makes for a subtle-yet-sophisticated light floral scent.
Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.


Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse .
Isopropyl Myristate can be added to formulas as is, add to oil phase.


Typical use level of Isopropyl Myristate is 1-20%.
Isopropyl Myristate is used for external use only.
Isopropyl Myristate is used Creams, lotions, hand creams, shampoo, shower gels, makeup removers, powders and foundations.


Isopropyl Myristate is a fast spreading emollient suitable for all cosmetic applications.
Applications of Isopropyl Myristate: Most often used at between 1-10%.
Isopropyl myristate is an emollient, it helps to strengthen the skin barrier, ensuring that moisture stays locked in.


As an emollient, Isopropyl Myristate also helps soften and smooth dry skin, which is why this is a great ingredient for those with dry or flaky skin.
This fabulous ingredient, Isopropyl Myristate, can also acts as a lubricant, thickening agent or a moisturiser in your cosmetic product.
Isopropyl Myristate is used to give your product a slicker, smoother feel rather than an oily one.


A colorless liquid with a faint odor, Isopropyl Myristate is used in many applications, including pharma, food and personal care product manufacturing.
Isopropyl Myristate is used in baby care & cleansing-, after sun-, color care-, body & face care- and sun protection products.
Isopropyl Myristate is also used in personal care wipes, antiperspirants & deodorants, conditioning, self-cleansing and self-tanning products.


Isopropyl Myristateis a very lightweight emollient and can be used like a carrier oil in many applications.
Isopropyl Myristate is a synthetic oil used as an emollient, thickening agent and lubricant in beauty and personal care products.
Isopropyl Myristate is composed of Isopropyl Alcohol (a propane derivative) and Myristic Acid (a naturally-occurring fatty acid), It is most often used an an additive in aftershaves, shampoos, bath oils, antiperspirants, deodorants, oral hygiene products, and various creams and lotions.


A unique characteristic of Isopropyl Myristate is its ability to reduce the greasy feel caused by the high oil content of other ingredients in a product.
This synthetic oil is often added to beauty products to give them a slicker, sheer feel rather than an oily one.
Isopropyl Myristate (IPM) is a virtually odourless solvent. Isopropyl Myristate is used as a cosmetic emollient and solvent to replace ethanol in non-alcoholic skin-perfumes.


Isopropyl Myristate has poor solubility with terpenes, crystals and resinoids but Ok if they are first blended with other materials.
Isopropyl Myristate is used as a solvent in perfumes for oil or wax products like candles, wax melts, massage oils, hair oil etc.
Isopropyl Myristate removes many types of make-up including (pax) pros-aide.


Isopropyl Myristate is however Not recommended as an everyday makeup remover.
Isopropyl Myristate is ideal for removing prosthetics gently and cleaning the skin.
Isopropyl Myristate is used Personal Care and Cosmetics, Emollient, Moisturizer, Thickening Agent in Creams and Lotions, Pharmaceuticals, Thickening Agent, Emollient, Moisturizer in Topical Medicinal Preparations, Flavor and Fragrance, and Solvent, Binder, Diluent


Isopropyl Myristate is used as an emulsifier, emollient, thickening agent, lubricant and moisturiser in cosmetic, personal care and pharmaceutical products.
Use in the oil phase of your formula to help Isopropyl Myristate absorb quicker and easier, as well as helping your product spread and glide smoothly on application.


Isopropyl Myristate is also commonly used in cosmetic manufacturing to make finished products feel smoother rather than oily.
Isopropyl Myristate is widely used in products such as creams & lotions, shampoos, shower gels, bath & baby oils, aftershaves, powders, foundations and makeup removers.


Isopropyl Myristate is used as a treatment for head lice, in tick and flea products for pets, as a solvent in perfumes, and in cosmetics and topical medicines where good absorption through the skin is desired.
Isopropyl Myristate should be used with caution as combining it with some toxic materials will cause the skin to absorb them more easily.


-Cosmetic Uses of Isopropyl Myristate:
*binding agents
*perfuming agents
*skin conditioning
*skin conditioning - emollient
*solvents


-Pharmacodynamics uses of Isopropyl myristate:
Isopropyl myristate is an emollient vehicle that is effective at enhancing the penetration of other medical agents that may be incorporated into the vehicle as active agents.
In one study, a 50:50 isopropanol-isopropyl myristate binary enhancer synergistically increased the transport of estradiol across a two-layer human epidermis in vitro.


-Skin care:
Isopropyl Myristate works as an emollient, thickener, and a lubricant in beauty products.
Isopropyl Myristate locks in the hydration, and enhances the penetration of other ingredients in the formulation.
Isopropyl myristate is an effective agent for solubilizing lanolin.
Therefore, isopropyl myristate is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content.
Isopropyl Myristate leaves the skin soft and smooth without an oily surface film.
It can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl Myristate's also fast-spreading meaning that it gives the formula a good, nice slip


-Hair care:
Isopropyl Myristate works as a hydrating agent, emollient, and enhancer.
Isopropyl Myristate hydrates the hair and the scalp and enhances the penetration of other ingredients in the formulation.
Isopropyl Myristate is not recommended for particularly thin hair, as it can make it appear greasy, or an oily scalp or hair, as it can lead to clogged pores



ISOPROPYL MYRISTATE IS A NEUTRAL VEGETABLE OIL USED FOR SEVERAL PURPOSES:
*Reed diffusers.
*Melt in liquid form.
*Achieving greater wax adhesion to glass in the case of a candle.
*Better fragrance diffusion of your candle as an additive
Isopropyl Myristate is a vegetable-based emulsifying agent.
*Isopropyl Myristate is a colorless and odorless oily liquid.
*Isopropyl Myristate allows for greater fragrance diffusion in your candle or reed diffuser.
*Isopropyl Myristate also helps to achieve a nice wax adhesion to the glass and create scented liquid blends.



BENEFITS OF ISOPROPYL MYRISTATE:
*Emollient, lubricant, surface tension modifier or moisturiser in beauty products with a dry skin feel.
*In cosmetic manufacturing Isopropyl Myristate is used to give the finished product a slicker, smoother feel rather than an oily one.
*Isopropyl Myristate also has a slight pigment wetting ability which can be useful in colour cosmetic applications.



RECOMMENDATIONS OF ISOPROPYL MYRISTATE:
*Aftershaves
*Shampoos
*Bath oils
*Anti-perspirants
*Various creams and lotions



ISOPROPYL MYRISTATE: USES AND CHARACTERISTICS:
Isopropyl myristate is notable for promoting the absorption of medicine and other products through the skin.
Isopropyl Myristate is commonly found in creams, lotions and topical medicines.
Isopropyl Myristate is also used as a thickening agent, emollient and moisturizer, as well as a solvent, binder and diluent in perfumes and food flavorings.



WHAT DOES ISOPROPYL MYRISTATE DO IN A FORMULATION?
*Emollient
*Perfuming
*Skin conditioning
*Viscosity controlling



SAFETY PROFILE OF ISOPROPYL MYRISTATE:
Isopropyl myristate is determined safe for use in cosmetics according to the Cosmetics Ingredient Review (CIR) panel.



ALTERNATIVES OF ISOPROPYL MYRISTATE:
*C1215 ALKYL BENZOATE
*COCOCAPRYLATE
*ISODODECANE



BENEFITS OF ISOPROPYL MYRISTATE FOR SKIN:
*Softens the skin:
As an emollient, Isopropyl Myristate helps soften and smooth dry skin, which is why this is a choice ingredient for those with dry or flaky skin.
*Enhances the penetration of other ingredients:
The exact mechanism by which this works isn't fully clear, but it's thought that isopropyl myristate changes the structure of the stratum corneum, the most external layer of the skin, making it easier for active ingredients to absorb.
In turn, this can make the skincare you're using more effective.
*Improves product texture:
This benefit doesn't relate exactly to the skin, but isopropyl myristate can make skincare products have that lush, creamy, but not oily feel.



TYPE OF INGREDIENT OF ISOPROPYL MYRISTATE:
Emollient, though it also acts as a thickening agent and lubricant in beauty products.



MAIN BENEFITS OF ISOPROPYL MYRISTATE:
Locks in hydration, enhances the penetration of other ingredients, thickens formulas, and makes those with a high oil content feel silky rather than greasy.



WHO SHOULD USE ISOPROPYL MYRISTATE:
Isopropyl myristate is ideal for anyone with normal to dry skin looking for moisturization benefits, according to Palep.



HOW OFTEN YOU CAN USE ISOPROPYL MYRISTATE:
For the best results, follow the directions on the product it's found in, though daily or twice daily use is generally fine.



ISOPROPYL MYRISTATE WORKS WELL WITH:
Isopropyl myristate works well with an assortment of active ingredients, says Solomon, which is why it's found in so many different types of products and formulas.



THICKENER, LUBRICANT, MOISTURIZER USES OF ISOPROPYL MYRISTATE:
Isopropyl Myristate is used as an emollient, thickening agent, lubricant or moisturizer in beauty products.
All-natural ester, Isopropyl Myristate is used to impart a dry yet moisturizing feel to skin creams.



SOLUBILIZER OF ISOPROPYL MYRISTATE:
Isopropyl Myristate is used to help solubilize actives such as sunscreens, vitamins and perfumes into a base.



BENEFITS OF ISOPROPYL MYRISTATE:
*Superior emollient for non-greasy bath, body and baby oils
*Lubricant and compression aid for pressed powders
*Light & non-tacky emollient for creams and lotions.
*Readily adsorbed by the skin
*When used at high concentrations it gently lifts makeup and surface dirt
*Gives gloss and shine to hair
*Resistant to oxidation (does not become rancid)
*Widely used as diluent for fragrance oils.



HOW TO USE ISOPROPYL MYRISTATE:
Because Isopropyl Myristate's found in so many different products and formulations, your best bet is to follow the instructions on any particular product.
Still, you're likely to be limited more by the actives in a product than minor ingredients like isopropyl myristate.



HOW TO WORK WITH ISOPROPYL MYRISTATE:
Include Isopropyl Myristate in the oil phase of your products; it can be hot or cold processed.



WHAT DOES ISOPROPYL MYRISTATE DO FOR SKIN?
Isopropyl Myristate is a moisturizer; it enhances the penetration of other ingredients, thickens formulas, and makes those with a high oil content feel silky rather than greasy.



HOW OFTEN SHOULD I USE ISOPROPYL MYRISTATE?
For the best results, follow the directions on the product Isopropyl Myristate's found in, though daily or twice daily use is generally fine.



MECHANISM OF ACTION, ISOPROPYL MYRISTATE:
As a pediculicide, isopropyl myristate is capable of physically coating the exoskeleton bodies of lice.
This physical coating subsequently immobilizes the lice and works to dissolve the wax covering on the insect exoskeleton and blocks the insects' airways, leading to death by dehydration.
Although this physical action of isopropyl myristate results in little lice resistance (given the lack of immunologic or chemical activity in this mechanism of action), the substance is also not ovicidal, which means any eggs that may have been laid by lice would not be affected.
Moreover, isopropyl myristate is capable of eliciting its pediculicide action in a contact time of only 10 minutes per each necessary administration.



ALTERNATIVES AND SUBSTITUTIONS OF ISOPROPYL MYRISTATE:
One could use a very absorbing carrier oil instead (something like camellia seed oil), but even the lightest carrier oils won’t dramatically reduce the greasy feeling of a heavier formula, meaning the end product will be much heavier/slower absorbing than originally intended.
You can experiment with other lightweight esters, like C12-15 Alkyl Benzoate or Coco-Caprylate.
They have different skin feels than isopropyl myristate (IPM), but they are nice and light!
You could try something like isododecane or cyclomethicone, but ingredients like that are very volatile, meaning they cannot be heated much and will evaporate out of the finished product over time if given the opportunity.



WHY DO WE USE ISOPROPYL MYRISTATE IN FORMULATIONS?
Isopropyl Myristate is included in formulas to dramatically reduce the greasy/oily feel; it’s brilliant in recipes with large amounts of butters that are famous for a heavier skin feel (like shea).
Isopropyl Myristate is also a great lightweight emollient; you can include it in recipes as an alternative to a liquid carrier oil to make for a lighter, faster-absorbing product.
At higher concentrations Isopropyl Myristate can also be used in products like makeup removers.



DO YOU NEED ISOPROPYL MYRISTATE?
No, but if you don’t like heavy/greasy products Isopropyl Myristate is an excellent thing to have around.



REFINED OR UNREFINED, ISOPROPYL MYRISTATE?
Isopropyl Myristate only exists as a refined product.



STRENGHTS OF ISOPROPYL MYRISTATE:
Isopropyl Myristate is so good at reducing the greasy feel of other ingredients that it is possible to make products that are primarily shea butter that don’t feel greasy.



WEAKNESSES, ISOPROPYL MYRISTATE:
Isopropyl Myristate is not typically considered “natural”.



PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL MYRISTATE:
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C17H34O2

Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg
CAS number: 110-27-0
EC number: 203-751-4
Hill Formula: C₁₇H₃₄O₂
Molar Mass: 270.45 g/mol
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility: Boiling Point: 192-193°C
Melting Point: 2-3°C
Solubility: Soluble in benzyl benzoate, ethyl lactate, paraffin oil
Insoluble in water
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 3 °C - lit.
Initial boiling point and boiling range: 193 °C at 27 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available

Flash point > 150 °C - open cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available
Density: 0,85 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Acid Value (mg KOH/g): 0.5 Max
Saponification Value (mg KOH/g): 206-211
Color (APHA): 30 Max
Moisture Content (%): 0.1 Max
Ash Content (%): 0.1 Max
Peroxide Value (meq/Kg): 0.6 Max
Viscosity (mPa.s) 20℃: 5-6
Density (g/cm3) 20℃: 0.852-0.855
Refractive Index 20℃: 1.434-1.437

APPEARANCE AT 20°: Clear mobile liquid / solid
COLOR: Colorless
ODOR: Nearly odorless, oily, fatty
OPTICAL ROTATION (°): 0 / 0
DENSITY AT 20°C (G/ML)): 0,848 - 0,856
REFRACTIVE INDEX ND20: 1,4320 - 1,4370
FLASHPOINT (°C): 155
SOLUBILITY: Insoluble in water
ASSAY (% GC): > 98
ACID VALUE (MG KOH/G): < 0,5
Appearance: A colorless or slightly yellow oily liquid
Ester content %: ≥98
Acid value(mg KOH/g): ≤0.5
Hazen(Color): ≤30
Refractive index: 1.434-1.438
Specific gravity(20℃): 0.850-0.855

Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.
Pounds per Gallon - (est).: 6.990 to 7.156
Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure: 0.000329 mmHg @ 25.00 °C. (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 7.253 (est)

Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.
Soluble in:
amyris wood oil
benzyl benzoate
benzyl salicylate
clove leaf oil
deluent for candle fragrances
ethyl acetoacetate
ethyl lactate
paraffin oil
water, 0.01354 mg/L @ 25 °C (est)
Insoluble in:
water
Similar Items:note
isoamyl myristate
butyl myristate
isobutyl myristate
ethyl myristate
hexyl myristate

Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility: IUPAC Name: propan-2-yl tetradecanoate
Molecular Weight: 270.45
Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChI: InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
Boiling Point: 167 °C at 9 mmHg
Melting Point: -5ºC
Flash Point: 29.6 dyne/cm Density: 0.864 g/cm³
Purity: 98%+
Density: 0.853 g/cm3
Solubility: Soluble in chloroform (slightly), ethyl acetate (slightly).
Appearance: Clear colorless oil
Storage: Room Temperature
EINECS: 203-751-4
Hazard Class: 6.1
Hazard Codes: Xi
HS Code: 29159080
Log P: 5.63910
MDL: MFCD00008982
PSA: 26.3
Refractive Index: 1.434-1.436
Risk Statements: R36/37/38
RTECS: XB8600000
Safety Statements: S26-S36
Stability: Stable.
Vapor Pressure: 0.000329mmHg at 25°C



FIRST AID MEASURES of ISOPROPYL MYRISTATE:
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOPROPYL MYRISTATE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ISOPROPYL MYRISTATE:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus
-Further information:
none



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL MYRISTATE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 30 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ISOPROPYL MYRISTATE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of ISOPROPYL MYRISTATE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available



SYNONYMS:
ISOPROPYL MYRISTATE
110-27-0
Isopropyl tetradecanoate
Estergel
Isomyst
Bisomel
Promyr
Tetradecanoic acid, 1-methylethyl ester
Deltyl Extra
Kesscomir
Tegester
Sinnoester MIP
Crodamol IPM
Plymoutm IPM
Starfol IPM
Unimate IPM
Kessco IPM
Stepan D-50
Emcol-IM
Wickenol 101
Emerest 2314
propan-2-yl tetradecanoate
1-Methylethyl tetradecanoate
Deltylextra
Myristic acid isopropyl ester
JA-FA IPM
Crodamol I.P.M.
Kessco isopropyl myristate
FEMA No. 3556
Tetradecanoic acid, isopropyl
Myristic acid, isopropyl ester
Tetradecanoic acid, isopropyl ester
Caswell No. 511E
HSDB 626
NSC 406280
Isopropyl myristate [USAN]
1-Tridecanecarboxylic acid, isopropyl ester
UNII-0RE8K4LNJS
0RE8K4LNJS
EINECS 203-751-4
Estergel (TN)
EPA Pesticide Chemical Code 000207
NSC-406280
BRN 1781127
methylethyl tetradecanoate
tetradecanoic acid 1-methylethyl ester
iso-Propyl N-tetradecanoate
Isopropyl myristate [USAN:NF]
DTXSID0026838
CHEBI:90027
EC 203-751-4
Tetradecanoic acid methyethyl ester
1405-98-7
NCGC00164071-01
WE(2:0(1Me)/14:0)
MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER
Isopropyl myristate, 98%
TETRADECONOIC ACID, 1-METHYLETHYL ESTER
DTXCID306838
ISOPROPYL MYRISTATE (II)
ISOPROPYL MYRISTATE [II]
ISOPROPYL MYRISTATE (MART.)
ISOPROPYL MYRISTATE [MART.]
ISOPROPYL MYRISTATE (USP-RS)
ISOPROPYL MYRISTATE [USP-RS]
CAS-110-27-0
ISOPROPYL MYRISTATE (EP MONOGRAPH)
ISOPROPYL MYRISTATE [EP MONOGRAPH]
MFCD00008982
Deltyextra
Tegosoft M
Liponate IPM
Crodamol 1PM
isopropyl-myristate
Lexol IPM
Crodamol I.P.M
isopropyl myristate
Isopropyltetradecanoate
myristic acid isopropyl
Radia 7190
Isopropyl myristate (NF)
Isopropyl tetradecanoic acid
MYRISTATE, ISOPROPYL
SCHEMBL2442
Myristic acid-isopropyl ester
Isopropyl myristate, >=98%
CHEMBL207602
ISOPROPYL MYRISTATE [MI]
WLN: 13VOY1&1
FEMA 3556
tetradecanoic acid isopropyl ester
ISOPROPYL MYRISTATE [FHFI]
ISOPROPYL MYRISTATE [HSDB]
ISOPROPYL MYRISTATE [INCI]
ISOPROPYL MYRISTATE [VANDF]
Isopropyl myristate, >=90% (GC)
Tox21_112080
Tox21_202065
Tox21_303171
ISOPROPYL MYRISTATE [WHO-DD]
LMFA07010677
NSC406280
s2428
AKOS015902296
Tox21_112080_1
DB13966
LS-2869
USEPA/OPP Pesticide Code: 000207
NCGC00164071-02
NCGC00164071-03
NCGC00256937-01
NCGC00259614-01
HY-124190
CS-0085813
FT-0629053
M0481
D02296
F71211
Isopropyl myristate
1-Methylethyl tetradecanoate
EN300-25299830
Q416222
SR-01000944751
Isopropyl myristate, Vetec(TM) reagent grade, 98%
Q-201418
SR-01000944751-1
Isopropyl myristate
Myristic acid, isopropyl ester
(Tetradecanoic acid, isopropyl
Isopropyl myristate)
InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H
Propan-2-yl tetradecanoate
Tetradecanoic acid, 1-methylethyl ester
Myristic acid isopropyl ester
IPM
IPM 100
IPM-EX
IPM-R
Isopropyl tetradecanoate
Myristic acid isopropyl ester
Tetradecanoic acid
1-methylethyl ester
Myristic acid, isopropyl ester
Bisomel
Crodamol I.P.M.
Crodamol IPM
Deltyl Extra
Emcol-IM
Isomyst
Isopropyl tetradecanoate
Kessco IPM
Kesscomir
Promyr
Sinnoester MIP
Stepan D-50
Wickenol 101
Emerest 2314
Estergel
Ja-fa IPM
Kessco isopropyl myristate
Plymoutm IPM
Starfol IPM
Tegester
Tetradecanoic acid, isopropyl
Tetradecanoic acid, isopropyl ester
Unimate IPM
1-Tridecanecarboxylic acid, isopropyl ester
D 50
1-Methylethyl tetradecanoate
IPM
Lexol IPM
Liponate IPM
Radia 7190
Tegosoft M
iso-Propyl N-tetradecanoate
Methylethyl tetradecanoate
Tetradecanoic acid methyethyl ester
NSC 406280
1405-98-7



ISOPROPYL MYRISTATE (IPM)
Isopropyl Myristate (IPM) is a fast spreading emollient suitable for all cosmetic applications.
Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid.


CAS Number: 110-27-0
EC Number: 203-751-4
MDL number: MFCD00008982
Linear Formula: CH3(CH2)12COOCH(CH3)2
Molecular Formula: C17H34O2



ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Isomyst, Bisomel, Promyr, Tetradecanoic acid, 1-methylethyl ester, Deltyl Extra, Kesscomir, Tegester, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Stepan D-50, Emcol-IM, Wickenol 101, Emerest 2314, propan-2-yl tetradecanoate, 1-Methylethyl tetradecanoate, Deltylextra, Myristic acid isopropyl ester, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, FEMA No. 3556, Tetradecanoic acid, isopropyl, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, HSDB 626, NSC 406280, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, tetradecanoic acid 1-methylethyl ester, iso-Propyl N-tetradecanoate, Isopropyl myristate [USAN:NF], DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], MFCD00008982, Deltyextra, Tegosoft M, Liponate IPM, Crodamol 1PM, isopropyl-myristate, Lexol IPM, Crodamol I.P.M, isopropyl myristate, Isopropyltetradecanoate, myristic acid isopropyl, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, MYRISTATE, ISOPROPYL, SCHEMBL2442, Myristic acid-isopropyl ester, Isopropyl myristate, >=98%, CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [INCI], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, LS-2869, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, HY-124190, CS-0085813, FT-0629053, M0481, D02296, F71211, Isopropyl myristate, 1-Methylethyl tetradecanoate, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, Isopropyl myristate, Myristic acid, isopropyl ester, (Tetradecanoic acid, isopropyl, Isopropyl myristate), InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, Propan-2-yl tetradecanoate, Tetradecanoic acid, 1-methylethyl ester, Myristic acid isopropyl ester, IPM, IPM 100, IPM-EX, IPM-R, Isopropyl tetradecanoate, Myristic acid isopropyl ester, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, 1405-98-7, ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Isomyst, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Promyr, Deltyl Extra, Kesscomir, Tegester, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Stepan D-50, Emcol-IM, propan-2-yl tetradecanoate, Wickenol 101, Emerest 2314, 1-Methylethyl tetradecanoate, Deltylextra, Myristic acid isopropyl ester, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, FEMA No. 3556, Tetradecanoic acid, isopropyl, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, HSDB 626, NSC 406280, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, MFCD00008982, iso-Propyl N-tetradecanoate, DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], IPM-EX, IPM-R, tetradecanoic acid 1-methylethyl ester, Deltyextra, Myristic acid-isopropyl ester, Tegosoft M, Isopropyl myristate [USAN:NF], Liponate IPM, Crodamol 1PM, IPM 100, isopropyl-myristate, Lexol IPM, Isopropyltetradecanoate, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, SCHEMBL2442, Isopropyl myristate, >=98%, CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [INCI], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, LS-14615, HY-124190, CS-0085813, FT-0629053, M0481, NS00006471, D02296, F71211, Isopropyl myristate, 1-Methylethyl tetradecanoate, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, Isopropyl myristate, United States Pharmacopeia (USP) Reference Standard, TETRADECANOIC ACID, ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER), Isopropyl myristate, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, component of Sardo Bath Oil, 1405-98-7



Isopropyl Myristate (IPM) is a multifunctional (emollient, solvent, spreading agent, penetrant) synthetically produced ester of vegetal myristic acid and petrochemical isopropyl alcohol that conforms to the requirements of the National Formulary monograph for Isopropyl Myristate.
Isopropyl Myristate (IPM) is non-occlusive, spreads well and provides an elegant, non-oily skin feel.


Isopropyl Myristate (IPM) is best stored in sealed containers kept in a cool, dry place.
Isopropyl Myristate (IPM) is prolonged storage, at temperatures above 90°F (32°C) should be avoided.
Isopropyl Myristate (IPM) is a fatty acid ester.


Isopropyl Myristate (IPM) is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.
Isopropyl Myristate (IPM) has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which Isopropyl Myristate (IPM) is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.


Isopropyl Myristate (IPM) is a natural product found in Solanum tuberosum, Siraitia grosvenorii, and other organisms with data available.
Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Isopropyl Myristate (IPM) is a slightly yellowish, transparent-looking liquid.


Isopropyl Myristate (IPM) is soluble in oil-based solvents and some organic compounds.
Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Isopropyl Myristate (IPM) mainly works as an emollient in cosmetics and personal care products.


Isopropyl Myristate (IPM) has an oily base with low viscosity and adapts well to the skin.
Isopropyl Myristate (IPM) is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Isopropyl Myristate (IPM) is used Cosmetic Grade for Soap Making, Fragrances, Shampoo, Creams & Lotion, Makeup & Adhesive Remover, Antiperspirants & Deodorants.


Isopropyl Myristate (IPM) can be used in some of the most demanding industrial applications and has been manufactured to the highest standards of eco-friendly management.
A colorless liquid with a faint odor, Isopropyl Myristate (IPM) is used in many applications, including pharma, food and personal care product manufacturing.


Isopropyl Myristate (IPM) is a polar emollient.
Isopropyl Myristate (IPM) is a synthetic oil composed of isopropyl alcohol, a propane derivative, and myristic acid, a naturally occurring fatty acid.
Isopropyl Myristate (IPM)'s a common cosmetic component in a wide range of beauty products, including aftershaves, antiperspirants, and anti-ageing lotions.


Isopropyl Myristate (IPM) is an ester of isopropanol and myristic acid. Isopropyl Myristate (IPM) is also referred to as tetradecanoic acid.
Isopropyl Myristate (IPM) is manufactured from vegetable oil sources to a minimum 98-percent purity.
Isopropyl Myristate (IPM) made from the combination of isopropyl alcohol and the naturally derived fatty acid myristic acid.


Isopropyl Myristate (IPM) helps gives a silky smooth and velvet texture when making cosmetics such as personal skin care products.
Isopropyl Myristate (IPM) is a virtually odourless solvent.
Isopropyl Myristate (IPM) is known for promoting the absorption of medicines and other products through the skin.


Isopropyl Myristate (IPM) is commonly found in creams, lotions and topical medicines.
In cosmetics, Isopropyl Myristate (IPM) is derived from isopropanol and myristic acid (a fatty acid naturally present in coconut and palm oils).
Isopropyl Myristate (IPM) is a very mild emollient that can be used as a carrier oil in a variety of applications.


Isopropyl Myristate (IPM) is included in formulations to dramatically reduce the sensation of greasiness and/or heaviness; it is excellent in formulations with a high content of butters known for their heavier skin feel (e.g. shea).
Isopropyl Myristate (IPM) is also an excellent mild skin softener and can be included in recipes as an alternative to liquid carrier oil for lighter and faster absorption.


Isopropyl Myristate (IPM) is an ester of Isopropyl alcohol and myristic acid.
This multi-purpose oil is an ester of isopropyl alcohol and myristic acid. The isopropyl component is a propane derivative; mystic acid is a fatty acid common in plant sources such as nutmeg and palm seeds. Isopropyl Myristate (IPM) possesses several unique characteristics which make it a valuable additive in many cosmetics and pharmaceutical products.


Certainly one of the most significant of these is the oil's ease of absorption by the skin.
Isopropyl Myristate (IPM) is used as an emollient in creams and lotions, isopropyl myristate ensures deep, quick penetration for these preparations.
Isopropyl Myristate (IPM) is also a common ingredient in pharmaceutical formulations.


Isopropyl Myristate (IPM) is a ester of isopropyl alcohol and myristic acid (vegetable-derived).
Isopropyl Myristate (IPM) has low viscosity fluid non-greasy emollient, tolerates wide pH range, compatible with most surfactants.
Thanks to its low viscosity and density, Isopropyl Myristate (IPM) has a high spreadability.


Isopropyl Myristate (IPM) provides a soft and silky feel.
Isopropyl Myristate (IPM) absorbs quickly.
Isopropyl Myristate (IPM) is a colorless oil-like liquid.


Isopropyl Myristate (IPM) has no or little odor.
Isopropyl Myristate (IPM) is soluble in Oil.
Isopropyl Myristate (IPM) is not Soluble in Water.


Isopropyl Myristate (IPM) is a non-branched saturated fatty acid ester obtained from isopropanol and myristic acid, from palm oil.
Isopropyl Myristate (IPM) is a clear liquid with a melting point of -3 ºC.
Isopropyl Myristate (IPM) is a ester of isopropyl alcohol and myristic acid (vegetable-derived).


Isopropyl Myristate (IPM) has low viscosity fluid non-greasy emollient, stable over a wide pH range, compatible with most surfactants, low viscosity and density - high spreadability.
Isopropyl Myristate (IPM) is colorless oil-like liquid with or little odor, water-insoluble, polar emollient and is used in cosmetics where good absorption into the skin is desired, being studied as a skin enhancer, in pet care products, also used as a solvent in perfume materials,


Isopropyl Myristate (IPM) is an ester of isopropanol and vegetable derived myristic acid.
Isopropyl Myristate (IPM) is an ester included in formulas to dramatically reduce the greasy/oily feel.
Isopropyl Myristate (IPM)’s works wonders in formulations like lotion bars for a glidy, smooth non-greasy feel.


Isopropyl Myristate (IPM) is a colourless, liquid synthetic oleochemical derived from esterized Myristic acid and Isopropyl alcohol.
Isopropyl Myristate (IPM) is an ester of isopropyl alcohol and myristic acid.
Isopropyl Myristate (IPM) is an extremely effective emollient and can act as a thickening or lubricating agent.


Isopropyl Myristate (IPM) is unique in that it enhances the penetration of other ingredients in a formulation, allowing for a variety of applications.
Include Isopropyl Myristate (IPM) in the oil phase of your products; it can be hot or cold processed.
Isopropyl Myristate (IPM) is an ester of isopropanol and vegetable derived myristic acid.


A unique property of Isopropyl Myristate (IPM) is its ability to reduce the greasy feeling caused by its high oil content.
Isopropyl Myristate (IPM) is easily absorbed into the skin and ensures rapid penetration of product ingredients.
Isopropyl Myristate (IPM) is insoluble in water.


At a concentration of more than 5% Isopropyl Myristate (IPM) can clog pores (it is comedogenic).
Isopropyl Myristate (IPM) is a clear, colorless oil-like liquid that makes the skin feel smooth and nice (aka emollient) and it does so without it being greasy.


Isopropyl Myristate (IPM) is a colorless, liquid oleochemical derived from esterized Myristic acid and Isopropyl alcohol.
Isopropyl Myristate (IPM) is a common ingredient in cosmetic products, particularly moisturizing personal care products like lotions, creams, or serums.
Isopropyl Myristate (IPM) is an extremely effective emollient and can act as a thickening or lubricating agent.


Isopropyl Myristate (IPM) is unique in that it enhances the penetration of other ingredients in a formulation, allowing for a variety of applications.
Isopropyl Myristate (IPM) carries RSPO-MB Certification, one of four certification levels offered by the RSPO which monitors the trade of sustainably certified and non-sustainably certified palm oil.


Hydrolisis of the ester from Isopropyl Myristate (IPM) can liberate the acid and the alcohol.
Isopropyl Myristate (IPM) could be responsible for the decreasing of the pH value of formulations
Isopropyl Myristate (IPM) has no odor.


Isopropyl Myristate (IPM) is not a food grade product.
Isopropyl Myristate (IPM) is produced using isopropyl alcohol and myristic acid via esterification process.
What's more, Isopropyl Myristate (IPM) can even reduce the heavy, greasy feel in products with high oil content.


Isopropyl Myristate (IPM)'s also fast-spreading meaning that it gives the formula a good, nice slip.
Isopropyl Myristate (IPM) absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper.
Thanks to all this, Isopropyl Myristate (IPM)'s one of the most commonly used emollients out there.


There is just one little drawback: Isopropyl Myristate (IPM) has a high comedogenic index (5 out of 5...), so it might clog pores if you're prone to it.
When used at recommended dosage Isopropyl Myristate (IPM), is considered safe for cosmetics and personal care products.
Isopropyl Myristate (IPM) is not a known allergen or skin irritant and has low toxicity when ingested.
Isopropyl Myristate (IPM) is a polar emollient that promotes the absorption of products to the skin.



USES and APPLICATIONS of ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) may be used as a carrier for cosmetic and pharmaceutical additives, and is also an excellent solubilizer for lanolin.
Hence Isopropyl Myristate (IPM) finds broad application in topically applied cosmetic and pharmaceutical liquid, cream, lotion, powder and spray products.
Isopropyl Myristate (IPM) is used in Skin Care, Hair Care, Baby Care, Nail Care, Lip Care, Cosmetics, Massage, and Aromatherapy.


Isopropyl Myristate (IPM) is used as a base for your perfumes and dry body oils.
Isopropyl Myristate (IPM) is used up to 99% as a perfume dilutant.
Isopropyl Myristate (IPM) is used in the fragrance world to dilute materials.


Isopropyl Myristate (IPM) is used in diffusers.
Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl Myristate (IPM) is also used as a solvent in perfume materials and in the removal process of prosthetic make-up.


Isopropyl Myristate (IPM) is used as a bath oil on its own or with another oil.
Isopropyl Myristate (IPM) is also used as a treatment for head lice.
Isopropyl Myristate (IPM) is also in flea and tick killing products for pets.


Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl Myristate (IPM) is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.
Isopropyl Myristate (IPM) is a fast spreading emollient suitable for all cosmetic applications.


Isopropyl Myristate (IPM) has the potential to soften and smooth the skin.
Isopropyl Myristate (IPM) helps moisturize the skin.
Isopropyl Myristate (IPM) supports the protection of the skin against environmental factors.


Isopropyl Myristate (IPM) ensures homogeneous mixing of other ingredients and increases the stability of the formulation.
Isopropyl Myristate (IPM) is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Hydrolysis of the ester from Isopropyl Myristate (IPM) can liberate the acid and the alcohol.


Isopropyl Myristate (IPM) is theorized to be responsible for decreasing of the pH value of formulations.
Isopropyl Myristate (IPM) is an emollient ester of low viscosity; the product of the reaction of isopropanol with myristic acid (vegetable source).
A non-greasy emollient, Isopropyl Myristate (IPM) is readily adsorbed by the skin.


Miscible with most oils, Isopropyl Myristate (IPM) imparts a dry, velvety emollience to products. Isopropyl Myristate (IPM) is used to reduce the greasiness of lotion bars, whipped butters and emulsions.
Isopropyl Myristate (IPM) is resistant to oxidation and will not become rancid.


Isopropyl Myristate (IPM) is also an effective diluent for fragrance oil.
In make up Isopropyl Myristate (IPM) is often used as a remover for prosthetic adhesives and Alcohol activated colours.
Isopropyl Myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption the skin is desired.


In make up Isopropyl Myristate (IPM) is often used as a remover for prosthetic adhesives and Alcohol activated colours.
SOLUBILIZER: Isopropyl Myristate (IPM) is used to help solubilize actives such as sunscreens, vitamins and perfumes into a base.
Isopropyl Myristate (IPM) is used as a cosmetic emollient and solvent to replace ethanol in non-alcoholic skin-perfumes.


Poor solubility with terpenes, crystals and resinoids but Ok if they are first blended with other materials.
Isopropyl Myristate (IPM) is used as a solvent in perfumes for oil or wax products like candles, wax melts, massage oils, hair oil etc.
Isopropyl Myristate (IPM) is also used as a thickener, emollient and humectant, solvent, binder and diluent in perfumes and food flavorings.


Isopropyl Myristate (IPM) can also be used to thicken cosmetic preparations.
In higher concentrations Isopropyl Myristate (IPM) can also be used in products such as make-up removers.
Isopropyl Myristate (IPM) is commonly found in products such as: creams, lotions, hand creams, shampoos, shower gels, make-up removers, powders and make-up foundations.


Application rates of Isopropyl Myristate (IPM) is range from 1 to 20%.
In the paint industry, Isopropyl Myristate (IPM) is used as a base and or solvent in the manufacture of writing instruments containing liquid or gel ink.
In medicine, Isopropyl Myristate (IPM) is used in topical pharmaceutical preparations where it is desired to be absorbed into the skin.


Isopropyl Myristate (IPM) is also used as a treatment for head lice.
Isopropyl Myristate (IPM) is a very effective remedy for head lice as a non-systemic agent.
Isopropyl Myristate (IPM) works by dissolving the wax covering the exoskeleton of the head lice, causing the insects to die due to dehydration (water loss).


One lesser known property of Isopropyl Myristate (IPM) is its ability to inhibit the growth of oral bacteria.
Isopropyl Myristate (IPM) is used by many manufacturers of oral hygiene products such as mouthwashes.
Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as a non-aqueous component of two-phase mouthwashes.


In veterinary medicine, Isopropyl Myristate (IPM) can be found in products for pets that kill fleas and ticks.
Isopropyl Myristate (IPM) can also be found in ear cleaning products to dissolve wax build-up without drying out the skin of the animal's ear.
Isopropyl Myristate (IPM) is commonly used as a lightweight emollient and is often added to body products to reduce the greasy feel left on the skin from some ingredients.


Isopropyl Myristate (IPM) can be used as a carrier oil and also as a diluent for perfume making.
Isopropyl Myristate (IPM) is a synthetic oil widely used in the cosmetics and pharmaceutical industries as a lubricant, emollient, and as a non-toxic alternative for controlling head lice.


The oil is manufactured by condensing myristic acid with isopropyl alcohol and is colorless and mild in odor.
Isopropyl Myristate (IPM) is often used as a non-pesticide alternative for treating head lice infestations.
The oil destroys the wax layer which insulates the lice and causes death by dehydration.


Isopropyl Myristate (IPM) is also effective at controlling oral bacteria and is used in several mouthwash products.
Isopropyl Myristate (IPM) is used Creams, lotions, hand creams, shampoo, shower gels, makeup removers, powders and foundations.
Isopropyl Myristate (IPM) can be added to formulas as is, add to oil phase.


Common use levels of Isopropyl Myristate (IPM) are lotions and creams 2-5% and bath oils 30-40%.
Isopropyl Myristate (IPM) is used for external use only.
Isopropyl Myristate (IPM) reduces the greasy feel of most oils, tacky feel of some additives, and acts as a dry emollient in cosmetic formulations.


Cosmetic formulations of Isopropyl Myristate (IPM): binding, fragrance, perfuming, emollient
Industrial uses of Isopropyl Myristate (IPM): manufacturer of washing and cleaning products, lubricants and greases, textile treatment products and dyes, polymers, adhesives, sealants, polishes and waxes.


Considered a dry emollient, Isopropyl Myristate (IPM) is primarily used to reduce the greasy feel of other oils and butters in skin care products such as lotions, creams and lotion bars.
Isopropyl Myristate (IPM) also aids in absorption, helping bring other ingredients deeper into the skin.


Common usage of Isopropyl Myristate (IPM) up to 10% added into your oil phase.
Isopropyl Myristate (IPM) is used formulations with large amounts of butters that are infamous for a heavier skin feel.
Try Isopropyl Myristate (IPM) in your whipped butters to reduce the heavy greasy feel.


Isopropyl Myristate (IPM) is a common ingredient in cosmetic products, particularly moisturizing personal care products like lotions, creams, or serums.
Considered a dry emollient, Isopropyl Myristate (IPM) is primarily used to reduce the greasy feel of other oils and butters in skin care products such as lotions, creams and lotion bars.


Isopropyl Myristate (IPM) also aids in absorption, helping bring other ingredients deeper into the skin.
Isopropyl Myristate (IPM) is used in cosmetic preparations as an emollient and in perfumes as a solvent.
Isopropyl Myristate (IPM) is also used in preparations against lice for humans and against fleas and ticks for animals.


Isopropyl Myristate (IPM) is most commonly found in after-shave products, shampoos, bath oils, antiperspirants and deodorants, oral hygiene products and various body lotions and skin creams.
Isopropyl Myristate (IPM) is used raw material for spin finishes and oiling agent for textile, Rubber processing agent, Plastic lubricant, Paint additive, Ink additive.


Isopropyl Myristate (IPM) is used cosmetic base.
Isopropyl Myristate (IPM) is used additives for pharmaceuticals.
Isopropyl Myristate (IPM) is a polar emoliant and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired.


Isopropyl Myristate (IPM) is being studied as a skin enhancer.
Isopropyl Myristate (IPM) is also used as a pesticide against head lice which works by dissolving the wax that covers the exoskeleton of head lice, killing them by dehydration.


Isopropyl Myristate (IPM) is used in the same way in flea and tick killing products for pets.
Isopropyl Myristate (IPM) is a flexible ingredient that can be used in creams, lip balms, perfumes, bath and body oils and even in room diffusers.
In creams, lotions and body butters Isopropyl Myristate (IPM)can be added for a sliky-soft feeling, sensuous glide when applying to skin. Use Isopropyl


Myristate (IPM) at up to 5% in creams, lotions and body butters.
Isopropyl Myristate (IPM) works as an emollient, thickening agent, lubricant, and texture enhancer in beauty products.
Isopropyl Myristate (IPM) helps to enhance the penetration of ingredients.


Isopropyl Myristate (IPM)'s non-greasy properties make formulas with high oil content feel silky.
Isopropyl Myristate (IPM) is miscible with most oils and a common carrier for fragrance oils.
Isopropyl Myristate (IPM) is favorite ingredient amongst formulators for its versatile application.


As Isopropyl Myristate (IPM) provides velvety emollience to products, it is used to reduce the greasiness of lotions, whipped butters, and emulsions.
There is also research showing Isopropyl Myristate (IPM) readily adsorbed by the skin.
Isopropyl Myristate (IPM) is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.


Isopropyl Myristate (IPM) has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which Isopropyl Myristate (IPM) is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.


Isopropyl Myristate (IPM) is a synthetic oil that is used as an emollient and solvent in personal care and cosmetic products.
Isopropyl Myristate (IPM) is a clear, colorless liquid that is miscible with most organic solvents including alcohol and propylene glycol.
In personal care products, Isopropyl Myristate (IPM) is used to dissolve other ingredients, give a smooth, silky feel to the skin and help products spread easily.


Isopropyl Myristate (IPM) is also used as a solvent for fragrances, and other active ingredients in products such as lotions, creams, ointments as well as make-up and hair care products.
Isopropyl Myristate (IPM) is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products such as aftershaves, shampoos, bath oils, antiperspirants, deodorants, oral hygiene products, and various creams and lotions.


A unique characteristic of Isopropyl Myristate (IPM) is its ability to reduce the greasy feel caused by the high oil content of other ingredients in a product.
Isopropyl Myristate (IPM) is often added to beauty products to give them a slicker, sheer feel rather than an oily one.


Isopropyl Myristate (IPM) is a fatty acid ester, which is used as solvent in water-in-oil emulsion, oils and fatty based ointments.
Membrane filtration is the Pharmacopoeia method of choice for sterility testing.
Isopropyl Myristate (IPM) is used in cosmetic preparations as an emollient and in perfumes as a solvent.


Viscous products, such as creams and ointments, can be difficult to filter and hence, are normally diluted in a sterile solvent, such as Isopropyl Myristate (IPM) to improve the filterability of these samples.
Isopropyl Myristate (IPM) is used in creams, lotions and topical pharmaceutical preparations as a thickening agent and where skin absorption is desired.


-THICKENER, LUBRICANT, MOISTURIZER uses of Isopropyl Myristate (IPM):
Emollient, thickening agent, lubricant or moisturizer in beauty products.
All-natural ester used to impart a dry yet moisturizing feel to skin creams.


-Solvent uses of Isopropyl Myristate (IPM):
Isopropyl Myristate (IPM) plays a key role in the dissolution of lanolin. Mixtures containing up to 50 % lanolin in Isopropyl Myristate (IPM) remain stable non-viscous liquids at room temperature.

The oil is therefore used as a solvent and penetrant in anhydrous skin lotions with high lanolin content.
Isopropyl Myristate (IPM) is used as a solvent for varnishes and paints, since the formulations used in the manufacture of paints and varnishes consist of many different organic substances.



WHAT IS ISOPROPYL MYRISTATE (IPM) USED FOR?
Isopropyl Myristate (IPM) is a texture enhancer and emollient as used in cosmetics.
Isopropyl Myristate (IPM) can also help to enhance the absorption of ingredients in a cosmetic formula.


*Skin care:
Isopropyl Myristate (IPM) works as an emollient, thickener, and a lubricant in beauty products.
Isopropyl Myristate (IPM) locks in the hydration, and enhances the penetration of other ingredients in the formulation.

Isopropyl Myristate (IPM) is an effective agent for solubilizing lanolin.
Therefore, Isopropyl Myristate (IPM) is used as a solubilizing, spreading, and penetrating agent in anhydrous skin lubricating lotions with high lanolin content.

Isopropyl Myristate (IPM) leaves the skin soft and smooth without an oily surface film.
Isopropyl Myristate (IPM) can even reduce the heavy, greasy feel in products with high oil content.
Isopropyl Myristate (IPM)'s also fast-spreading meaning that it gives the formula a good, nice slip


*Hair care:
Isopropyl Myristate (IPM) works as a hydrating agent, emollient, and enhancer.
Isopropyl Myristate (IPM) hydrates the hair and the scalp and enhances the penetration of other ingredients in the formulation.
Isopropyl Myristate (IPM) is not recommended for particularly thin hair, as it can make it appear greasy, or an oily scalp or hair, as it can lead to clogged pores



BENEFITS AND APPLICATIONS OF ISOPROPYL MYRISTATE (IPM):
*The use of isopropyl myristate in skincare products has the advantage of assisting in the dissolution of other skincare components, enabling them to be dispersed uniformly throughout the formulation.

*Isopropyl Myristate (IPM) is especially beneficial for dry and flaky skin as it acts as a brilliant emollient and helps in softening and smoothing your skin.

*Isopropyl Myristate (IPM) also eliminates germs, which is one of its key advantages.
As a result, Isopropyl Myristate (IPM) is frequently used in hand sanitizers.
This, together with the fact that Isopropyl Myristate (IPM) evaporates quickly, makes it an excellent component in both skincare and hand sanitizer products.

*Isopropyl Myristate (IPM) works as an emollient for your DIY formulation, which increases the product’s spreadability and improves texture.
Isopropyl Myristate (IPM) is special in that it can improve the penetration of other substances.

*Isopropyl Myristate (IPM) is incredibly necessary when formulating and making cosmetically elegant goods.



HOW ISOPROPYL MYRISTATE (IPM) WORKS?
Isopropyl Myristate (IPM) works by attracting moisture from the air and fixing it in the deep layers of skin and scalp.
Isopropyl Myristate (IPM) works by creating a preventive barrier that locks moisture into the skin and increases the moisture retention capacity.



CONCENTRATION AND SOLUBILITY OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is recommended that it should be used at a concentration of 1 to 20%.
Isopropyl Myristate (IPM) is soluble in most solvents but is insoluble in water.



HOW TO USE ISOPROPYL MYRISTATE (IPM):
Prepare the oil and water phases of your formulation separately.
Heat the water and oil phase using a double boiler.
Add Isopropyl Myristate (IPM) to the heated oil phase with constant stirring.
Blend both the phases using a mini-mixer until the required consistency is not obtained.



ORIGIN OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is commercially produced by distillation, before which the esterification of myristic acid and isopropanol is carried out, and the resulting alkali is refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.



WHAT DOES ISOPROPYL MYRISTATE (IPM) DO IN A FORMULATION?
*Emollient
*Perfuming
*Skin conditioning
*Viscosity controlling



SAFETY PROFILE OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is determined safe for use in cosmetics according to the Cosmetics Ingredient Review (CIR) panel.



ALTERNATIVES OF ISOPROPYL MYRISTATE (IPM):
*C1215 ALKYL BENZOATE,
*COCOCAPRYLATE,
*ISODODECANE



KEY PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
*Water insoluble
*Clear, colourless, oil-like
*Good skin absorption in moisturisers
*Emollient
*Halal
*Kosher
*Non-GMO
*RSPO MB available



MAIN FUNCTIONS OF ISOPROPYL MYRISTATE (IPM):
*Binding agent :
Isopropyl Myristate (IPM) allows different cosmetic ingredients to adhere together.

*Emollient :
Isopropyl Myristate (IPM) softens and smooths the skin

*Masking :
Isopropyl Myristate (IPM) reduces or suppresses the odor or main flavor of the product

*Fragrance:
Isopropyl Myristate (IPM) is used in the manufacture of perfumes and aromatic raw materials
Percentage of ingredients of natural origin according to ISO 16128: 78 %.



BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Superior emollient for non-greasy bath, body and baby oils
*Lubricant and compression aid for pressed powders
*Light & non-tacky emollient for creams and lotions. Readily adsorbed by the skin
*When used at high concentrations it gently lifts makeup and surface dirt
*Gives gloss and shine to hair
*Resistant to oxidation (does not become rancid)
*Widely used as diluent for fragrance oils.



FEATURES & BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Biodegradable
*Emollient
*80% reduction in VOCs compared with Texanol: meets and exceeds international regulations for no VOCs
*Fragrance Extender
*Lubricant
*Nonocclusive
*Nonoily
*Plant Derived / Vegetal Based
*Spreading Agent
*USP / NF Grade



WHY PEOPLE USE ISOPROPYL MYRISTATE (IPM):
To provide emollient properties to products.



POPULAR PRODUCTS THAT USE ISOPROPYL MYRISTATE (IPM):
*Lotions.
*Creams.



INTERESTING FACTS OF ISOPROPYL MYRISTATE (IPM):
*Emollient (softens skin).
*Counteracts the “oily” feel in some lotions.
*Provides a soft and silky feel.
*Absorbs quickly.



PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
Cosmetic and pharmaceutical uses of Isopropyl Myristate (IPM): Oil base with low viscosity, good adaptation to skin.
Isopropyl Myristate (IPM) is a colorless no odor.
Isopropyl Myristate (IPM) is suitable for cream-milk lotion, emollient and shampoo.



PHARMACODYNAMICS OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is an emollient vehicle that is effective at enhancing the penetration of other medical agents that may be incorporated into the vehicle as active agents.
In one study, a 50:50 isopropanol-Isopropyl Myristate (IPM)e binary enhancer synergistically increased the transport of estradiol across a two-layer human epidermis in vitro.



MECHANISM OF ACTION OF ISOPROPYL MYRISTATE (IPM):
As a pediculicide, Isopropyl Myristate (IPM) is capable of physically coating the exoskeleton bodies of lice.
This physical coating subsequently immobilizes the lice and works to dissolve the wax covering on the insect exoskeleton and blocks the insects' airways, leading to death by dehydration.

Although this physical action of Isopropyl Myristate (IPM) results in little lice resistance (given the lack of immunologic or chemical activity in this mechanism of action), the substance is also not ovicidal, which means any eggs that may have been laid by lice would not be affected. Moreover, Isopropyl Myristate (IPM) is capable of eliciting its pediculicide action in a contact time of only 10 minutes per each necessary administration 8,9,3,4.



PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL MYRISTATE (IPM):
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C17H34O2

Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg
CAS number: 110-27-0
EC number: 203-751-4
Hill Formula: C₁₇H₃₄O₂
Molar Mass: 270.45 g/mol
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility: Boiling Point: 192-193°C
Melting Point: 2-3°C

Solubility: Soluble in benzyl benzoate, ethyl lactate, paraffin oil
Insoluble in water
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 3 °C - lit.
Initial boiling point and boiling range: 193 °C at 27 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point > 150 °C - open cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available
Density: 0,85 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Acid Value (mg KOH/g): 0.5 Max
Saponification Value (mg KOH/g): 206-211
Color (APHA): 30 Max
Moisture Content (%): 0.1 Max

Ash Content (%): 0.1 Max
Peroxide Value (meq/Kg): 0.6 Max
Viscosity (mPa.s) 20℃: 5-6
Density (g/cm3) 20℃: 0.852-0.855
Refractive Index 20℃: 1.434-1.437
APPEARANCE AT 20°: Clear mobile liquid / solid
COLOR: Colorless
ODOR: Nearly odorless, oily, fatty
OPTICAL ROTATION (°): 0 / 0
DENSITY AT 20°C (G/ML)): 0,848 - 0,856
REFRACTIVE INDEX ND20: 1,4320 - 1,4370
FLASHPOINT (°C): 155
SOLUBILITY: Insoluble in water
ASSAY (% GC): > 98
ACID VALUE (MG KOH/G): < 0,5
Appearance: A colorless or slightly yellow oily liquid
Ester content %: ≥98
Acid value(mg KOH/g): ≤0.5

Hazen(Color): ≤30
Refractive index: 1.434-1.438
Specific gravity(20℃): 0.850-0.855
Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.
Pounds per Gallon - (est).: 6.990 to 7.156
Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure: 0.000329 mmHg @ 25.00 °C. (est)

Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 7.253 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers,
protected from heat and light.
Soluble in: amyris wood oil,
benzyl benzoate, benzyl salicylate,
clove leaf oil, deluent for candle fragrances,
ethyl acetoacetate, ethyl lactate,
paraffin oil, water, 0.01354 mg/L @ 25 °C (est),
Insoluble in: water,
Similar Items:note
isoamyl myristate, butyl myristate, isobutyl myristate,
ethyl myristate, hexyl myristate
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)

Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility: IUPAC Name: propan-2-yl tetradecanoate
Molecular Weight: 270.45
Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChI: InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
Boiling Point: 167 °C at 9 mmHg
Melting Point: -5ºC
Flash Point: 29.6 dyne/cm Density: 0.864 g/cm³
Purity: 98%+
Density: 0.853 g/cm3

Solubility: Soluble in chloroform (slightly), ethyl acetate (slightly).
Appearance: Clear colorless oil
Storage: Room Temperature
EINECS: 203-751-4
Hazard Class: 6.1
Hazard Codes: Xi
HS Code: 29159080
Log P: 5.63910
MDL: MFCD00008982
PSA: 26.3
Refractive Index: 1.434-1.436
Risk Statements: R36/37/38
RTECS: XB8600000
Safety Statements: S26-S36
Stability: Stable.
Vapor Pressure: 0.000329mmHg at 25°C
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Coun: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID MEASURES of ISOPROPYL MYRISTATE (IPM):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOPROPYL MYRISTATE (IPM):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ISOPROPYL MYRISTATE (IPM):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus
-Further information:
none



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL MYRISTATE (IPM):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 30 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ISOPROPYL MYRISTATE (IPM):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of ISOPROPYL MYRISTATE (IPM):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


ISOPROPYL MYRISTATE (IPM)

Isopropyl Myristate (IPM) is a clear, colorless liquid with a faint odor.
Isopropyl Myristate (IPM) has a smooth and silky texture, making it pleasant to apply to the skin.
Isopropyl Myristate (IPM) is widely used in cosmetics and personal care products.
Isopropyl Myristate (IPM) acts as an effective emollient, leaving the skin feeling soft and smooth.

CAS Number: 110-27-0
EC Number: 203-751-4

IPM, Isopropyl Tetradecanoate, Myristic Acid Isopropyl Ester, Tetradecanoic Acid Isopropyl Ester, Isopropyl Ester of Myristic Acid, Myristate Isopropyl, Isopropyl Myristate (IPM) Ester, 1-Methylethyl Tetradecanoate, IPM Ester, Tetradecanoic Acid, 1-Methylethyl Ester, Iso-Myristate, Ester of Isopropyl Alcohol and Myristic Acid, Isopropyl Ester of Tetradecanoic Acid, Isopropyl Myristate (IPM) IPM, Isopropyl Ester of Tetradecanoic Acid, Isopropyl Myristate (IPM) Solution, Isopropyl Ester Tetradecanoic Acid, Myristic Acid Isopropyl Alcohol Ester, Ester with Isopropyl Alcohol and Myristic Acid, Myristic Acid, Isopropyl Ester, IPM (Isopropyl Myristate (IPM)), Myristic Acid Isopropyl Ester IPM, Isopropyl Myristate (IPM) Myristate, Isopropyl Tetradecanoate IPM, Isopropyl Myristate (IPM) Esters, Tetradecanoic Acid, Isopropyl Ester, Isopropyl Myristate (IPM) IPM (Isopropyl Myristate (IPM)), Tetradecanoic Acid, Isopropyl Ester, IPM, Tetradecanoic Acid Isopropyl Ester (IPM), Myristic Acid, Isopropyl Ester (IPM), Tetradecanoic Acid, Isopropyl Ester (IPM), Myristic Acid, Isopropyl Ester (IPM), Isopropyl Tetradecanoate (IPM), Myristic Acid Isopropyl Ester (IPM), Tetradecanoic Acid, 1-Methylethyl Ester (IPM), Isopropyl Myristate (IPM) Liquid (IPM), Isopropyl Ester Myristic Acid (IPM), Isopropyl Myristate (IPM) Solution (IPM), Isopropyl Myristate (IPM) IPM (Isopropyl Myristate (IPM)), Tetradecanoic Acid, Isopropyl Ester, IPM, Tetradecanoic Acid Isopropyl Ester (IPM), Myristic Acid Isopropyl Ester (IPM), Tetradecanoic Acid, Isopropyl Ester (IPM), Myristic Acid, Isopropyl Ester (IPM), Isopropyl Tetradecanoate (IPM), Myristic Acid Isopropyl Ester (IPM), Tetradecanoic Acid, 1-Methylethyl Ester (IPM), Isopropyl Myristate (IPM) Liquid (IPM), Isopropyl Ester Myristic Acid (IPM), Isopropyl Myristate (IPM) Solution (IPM), Isopropyl Myristate (IPM) IPM (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) IPM (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) IPM Ester (Isopropyl Myristate (IPM)), IPM Ester of Isopropyl Alcohol and Myristic Acid (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) Ester (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) Solution (Isopropyl Myristate (IPM)), Isopropyl Ester Tetradecanoic Acid (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) Liquid (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) IPM Esters (Isopropyl Myristate (IPM)), Isopropyl Myristate (IPM) Myristate (Isopropyl Myristate (IPM))



APPLICATIONS


Isopropyl Myristate (IPM) is commonly used in skincare products such as creams, lotions, and moisturizers.
Isopropyl Myristate (IPM) serves as an emollient in these formulations, helping to soften and smooth the skin.
Isopropyl Myristate (IPM) is often included in sunscreen formulations for its lightweight texture and moisturizing properties.

Isopropyl Myristate (IPM) acts as a solvent in makeup products, aiding in the dispersion of pigments and ensuring even application.
Isopropyl Myristate (IPM) is used in facial cleansers and makeup removers to help dissolve and remove makeup and impurities.

Isopropyl Myristate (IPM) is a key ingredient in massage oils and body oils, providing a smooth glide and moisturizing effect.
Isopropyl Myristate (IPM) is added to hair care products such as conditioners and hair serums to improve manageability and reduce frizz.

Isopropyl Myristate (IPM) is used in antiperspirants and deodorants for its skin-soothing properties and ability to improve the spreadability of the product.
Isopropyl Myristate (IPM) is included in bath oils and bath bombs to enhance the moisturizing and emollient effects.

Isopropyl Myristate (IPM) is used in pharmaceutical preparations such as topical creams and ointments for its skin penetration-enhancing properties.
Isopropyl Myristate (IPM) is employed in insect repellents to improve the spreadability and efficacy of the active ingredients.

Isopropyl Myristate (IPM) is added to lip balms and lipsticks to provide a smooth, moisturizing texture.
Isopropyl Myristate (IPM) is used in shaving creams and foams to improve razor glide and reduce friction on the skin.

Isopropyl Myristate (IPM) serves as a carrier oil in aromatherapy blends, helping to dilute essential oils and enhance their absorption into the skin.
Isopropyl Myristate (IPM) is incorporated into baby care products such as diaper creams and lotions for its gentle and moisturizing properties.
It is used in foot care products such as foot creams and balms to soften rough skin and calluses.
Isopropyl Myristate (IPM) is added to hand sanitizers and hand creams for its moisturizing and emollient effects.

Isopropyl Myristate (IPM) is included in aftershave lotions and balms to soothe and hydrate the skin after shaving.
Isopropyl Myristate (IPM) is used in fragrance formulations to enhance the longevity and diffusion of the scent.

Isopropyl Myristate (IPM) serves as a carrier oil in essential oil blends for aromatherapy and massage therapy.
Isopropyl Myristate (IPM) is added to self-tanning products to improve the spreadability and evenness of application.

Isopropyl Myristate (IPM) is used in wound care products such as antiseptic creams and ointments for its skin-soothing properties.
Isopropyl Myristate (IPM) is included in hair removal creams and waxes to help dissolve and remove hair effectively.

Isopropyl Myristate (IPM) is used in cuticle creams and nail treatments to soften and moisturize the cuticles and nails.
Isopropyl Myristate (IPM) finds applications in a wide range of personal care and cosmetic products due to its versatile properties and benefits for the skin and hair.

Isopropyl Myristate (IPM) is commonly used in the formulation of sunscreens to enhance the spreadability and absorption of UV filters.
It is added to anti-aging creams and serums to improve the delivery of active ingredients such as retinoids and antioxidants.
Isopropyl Myristate (IPM) is included in lip glosses and lip balms to create a smooth and glossy texture.

Isopropyl Myristate (IPM) is used in hand lotions and creams to moisturize and soften dry, rough hands.
Isopropyl Myristate (IPM) is employed in foot scrubs and exfoliating creams to help remove dead skin cells and soften calluses.

Isopropyl Myristate (IPM) is added to bath salts and bath bombs to enhance the moisturizing properties and create a luxurious bathing experience.
Isopropyl Myristate (IPM) is used in cold creams and night creams to provide deep hydration and nourishment to the skin.

Isopropyl Myristate (IPM) is included in barrier creams and ointments to protect the skin from irritants and moisture loss.
Isopropyl Myristate (IPM) is added to hair masks and deep conditioning treatments to improve the softness and manageability of the hair.

Isopropyl Myristate (IPM) is used in cuticle oils and treatments to moisturize and soften the cuticles, promoting healthy nail growth.
Isopropyl Myristate (IPM) is included in body scrubs and exfoliating gels to help remove dead skin cells and reveal smoother, softer skin.
It is added to hand sanitizing gels and wipes to improve the spreadability and skin-feel of the product.
Isopropyl Myristate (IPM) is used in pre-shave oils and serums to soften the beard hair and prepare the skin for shaving.

Isopropyl Myristate (IPM) is included in makeup primers to create a smooth and even base for foundation application.
Isopropyl Myristate (IPM) is added to self-tanning lotions and sprays to improve the spreadability and evenness of application.

Isopropyl Myristate (IPM) is used in anti-cellulite creams and treatments to improve the absorption of active ingredients and promote smoother skin.
Isopropyl Myristate (IPM) is included in body powders and talcs to improve the spreadability and absorption of the powder.
It is added to scalp treatments and hair oils to moisturize the scalp and improve the health of the hair follicles.
Isopropyl Myristate (IPM) is used in aromatherapy massage oils to dilute essential oils and enhance their absorption into the skin.

Isopropyl Myristate (IPM) is included in eye makeup removers to help dissolve and remove waterproof mascara and eyeliner.
Isopropyl Myristate (IPM) is added to acne treatments and spot treatments to improve the penetration of active ingredients into the skin.

Isopropyl Myristate (IPM) is used in wound healing creams and ointments to soothe irritated skin and promote faster healing.
Isopropyl Myristate (IPM) is included in stretch mark creams and oils to moisturize and soften the skin, reducing the appearance of stretch marks.

Isopropyl Myristate (IPM) is added to baby oil formulations to provide gentle moisturization and softness to baby's delicate skin.
Isopropyl Myristate (IPM) finds applications in a wide range of personal care and cosmetic products, contributing to their effectiveness and pleasant sensory properties.

Isopropyl Myristate (IPM) is used in hair styling products such as gels and mousses to improve texture and hold.
Isopropyl Myristate (IPM) is added to bath oils and shower gels to provide a luxurious and moisturizing bathing experience.
Isopropyl Myristate (IPM) is used in hand creams and lotions for its quick-absorbing and non-greasy texture.

Isopropyl Myristate (IPM) is included in body butters and creams to provide long-lasting hydration and nourishment to the skin.
Isopropyl Myristate (IPM) is added to shaving creams and gels to improve razor glide and prevent irritation.

Isopropyl Myristate (IPM) is used in makeup setting sprays to help set makeup and prolong its wear.
Isopropyl Myristate (IPM) is included in anti-fungal creams and ointments for its skin-penetrating properties.

Isopropyl Myristate (IPM) is added to foot creams and balms to soften rough heels and calluses.
Isopropyl Myristate (IPM) is used in scar treatment products to improve the appearance of scars and stretch marks.

Isopropyl Myristate (IPM) is included in cuticle creams and oils to moisturize and soften dry cuticles.
Isopropyl Myristate (IPM) is added to sunscreen lotions and sprays to improve the spreadability and coverage.

Isopropyl Myristate (IPM) is used in lip scrubs and exfoliants to remove dead skin cells and soften chapped lips.
Isopropyl Myristate (IPM) is included in body washes and shower creams for its gentle cleansing properties.

Isopropyl Myristate (IPM) is added to massage creams and oils for its smooth glide and non-sticky feel.
Isopropyl Myristate (IPM) is used in hair serums and oils to add shine and reduce frizz.
It is included in hand sanitizing wipes and pads for its quick-drying and non-sticky texture.
Isopropyl Myristate (IPM) is added to body mists and sprays to provide a light, refreshing fragrance.

Isopropyl Myristate (IPM) is used in intimate lubricants and gels for its moisturizing and lubricating properties.
Isopropyl Myristate (IPM) is included in foot sprays and powders to prevent odor and moisture buildup.

Isopropyl Myristate (IPM) is added to makeup remover wipes and pads to help dissolve and lift away makeup.
Isopropyl Myristate (IPM) is used in anti-itch creams and lotions to soothe irritated skin.

Isopropyl Myristate (IPM) is included in baby lotions and oils for its gentle and moisturizing properties.
Isopropyl Myristate (IPM) is added to cuticle removers and softeners to gently remove excess cuticle.

Isopropyl Myristate (IPM) is used in hair detangling sprays and leave-in conditioners for its smoothing and conditioning effects.
Isopropyl Myristate (IPM) finds applications in a wide range of cosmetic and personal care products, contributing to their efficacy and sensory appeal.



DESCRIPTION


Isopropyl Myristate (IPM) is a clear, colorless liquid with a faint odor.
Isopropyl Myristate (IPM) has a smooth and silky texture, making it pleasant to apply to the skin.

Isopropyl Myristate (IPM) is widely used in cosmetics and personal care products.
Isopropyl Myristate (IPM) acts as an effective emollient, leaving the skin feeling soft and smooth.

Isopropyl Myristate (IPM) has excellent moisturizing properties, helping to hydrate and nourish the skin.
Isopropyl Myristate (IPM) forms a thin, non-greasy film on the skin, providing long-lasting hydration.
Isopropyl Myristate (IPM) enhances the spreadability of cosmetic formulations, allowing for smooth and even application.
Isopropyl Myristate (IPM) has a lightweight and non-comedogenic formula, suitable for all skin types.

Isopropyl Myristate (IPM) helps to improve the texture of skincare products, giving them a luxurious and silky feel.
Isopropyl Myristate (IPM) can act as a solvent, aiding in the dispersion of pigments and other ingredients.

Isopropyl Myristate (IPM) has a low viscosity, making it easy to incorporate into various cosmetic formulations.
Isopropyl Myristate (IPM) is compatible with a wide range of other cosmetic ingredients, enhancing their performance.

Isopropyl Myristate (IPM) can improve the stability of emulsions and prevent the separation of oil and water phases.
Isopropyl Myristate (IPM) is gentle on the skin and suitable for use in sensitive areas.
Isopropyl Myristate (IPM) has a soothing effect on the skin, helping to alleviate dryness and discomfort.
Isopropyl Myristate (IPM) has been shown to increase the penetration of active ingredients into the skin.

Isopropyl Myristate (IPM) can be used in formulations for facial cleansers, moisturizers, serums, and lotions.
Isopropyl Myristate (IPM) is often included in hair care products such as conditioners and styling creams.

Isopropyl Myristate (IPM) helps to reduce frizz and enhance the manageability of hair.
Isopropyl Myristate (IPM) has a wide range of industrial applications beyond cosmetics, including pharmaceuticals and lubricants.

Isopropyl Myristate (IPM) is non-toxic and safe for topical use when used as directed.
Isopropyl Myristate (IPM) is readily biodegradable, minimizing its environmental impact.

Isopropyl Myristate (IPM) is stable under normal storage conditions, with a long shelf life.
Isopropyl Myristate (IPM) can be easily incorporated into DIY skincare formulations at home.
Isopropyl Myristate (IPM) is a versatile and effective ingredient that offers numerous benefits for skincare and hair care products.



PROPERTIES


Physical Properties:

Appearance: Clear, colorless to pale yellow liquid
Odor: Faint characteristic odor
Texture: Smooth and silky
Solubility: Insoluble in water, soluble in organic solvents such as ethanol, acetone, and ether
Density: Approximately 0.853 g/cm³
Melting Point: Ranges from around -10°C to -5°C
Boiling Point: Ranges from approximately 200°C to 230°C
Flash Point: Typically above 100°C
Vapor Pressure: Low
Viscosity: Low-viscosity liquid


Chemical Properties:

Chemical Formula: C17H34O2
Molecular Weight: Approximately 270.46 g/mol
Chemical Structure: Ester formed by the esterification of isopropyl alcohol and myristic acid (tetradecanoic acid)
Hydrophilic-Lipophilic Balance (HLB): Low HLB value, indicating lipophilic nature



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
If breathing is difficult, provide oxygen if available and seek medical attention promptly.
Keep the affected person warm and at rest.
If breathing has stopped, provide artificial respiration.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected skin area thoroughly with soap and water.
If irritation develops or persists, seek medical advice.
Do not rub the affected area excessively, as this may exacerbate irritation.
Apply a soothing and moisturizing cream or lotion to alleviate discomfort.


Eye Contact:

Flush the eyes gently with lukewarm water for at least 15 minutes, holding the eyelids open.
Seek immediate medical attention, even if irritation or discomfort is minimal.
Remove contact lenses, if present and easily removable, after flushing the eyes.
Continue rinsing the eyes with water until medical help arrives.


Ingestion:

Do not induce vomiting unless instructed to do so by medical personnel.
Rinse the mouth thoroughly with water, but do not swallow.
Seek immediate medical attention or contact a poison control center.
If the person is conscious, give small sips of water to drink.


General First Aid:

If symptoms persist or worsen, seek medical advice promptly.
Provide supportive care as needed, including rest and hydration.
Keep the affected person warm and comfortable.
Do not apply any ointments, creams, or other topical treatments unless instructed by a healthcare professional.
If medical attention is required, provide information about the product involved, including its name and composition.



HANDLING AND STORAGE


Handling:

Wear appropriate personal protective equipment (PPE), including safety glasses, gloves, and protective clothing, when handling Isopropyl Myristate (IPM).
Avoid prolonged or repeated skin contact with the substance.
In case of contact, wash skin thoroughly with soap and water.
Use in a well-ventilated area to prevent the buildup of vapors.
Avoid inhalation of vapors or mist.
If ventilation is inadequate, use respiratory protection, such as a NIOSH-approved respirator.
Do not eat, drink, or smoke while handling Isopropyl Myristate (IPM).
Keep containers tightly closed when not in use to prevent contamination and minimize evaporation.
Use appropriate handling equipment, such as pumps or dispensing tools, to minimize spills and splashes.
Do not use compressed air for transferring Isopropyl Myristate (IPM), as it may generate aerosols.


Storage:

Store Isopropyl Myristate (IPM) in a cool, dry, and well-ventilated area away from heat, sparks, and open flames.
Keep containers tightly closed and upright to prevent leakage and spills.
Store away from incompatible materials, such as strong oxidizing agents and acids.
Ensure storage area is equipped with adequate fire detection and suppression systems.
Store away from direct sunlight and sources of ignition.
Do not store Isopropyl Myristate (IPM) near food, beverages, or animal feed.
Store in containers made of compatible materials, such as high-density polyethylene (HDPE) or stainless steel.
Check containers regularly for signs of damage or deterioration and replace if necessary.
Keep storage area clean and free from debris to minimize the risk of contamination.
Follow all local regulations and guidelines for the storage of hazardous chemicals.


Transportation:

Transport Isopropyl Myristate (IPM) in accordance with local regulations and applicable transportation laws.
Use appropriate packaging and labeling to identify the substance and its hazards during transportation.
Ensure containers are securely sealed and properly labeled to prevent leakage and spills.
Use suitable means of transportation, such as covered vehicles, to protect Isopropyl Myristate (IPM) from exposure to environmental elements.
Follow all safety precautions and handling instructions provided by the manufacturer or supplier during transportation.
In case of spills or leaks during transportation, follow appropriate cleanup procedures and notify relevant authorities.
ISOPROPYL MYRISTATE (IPM)
Isopropyl myristate (IPM) is an emollient ester of low viscosity; light weight oil.
Isopropyl Myristate (IPM) is a slightly yellowish, transparent-looking liquid.


CAS Number: 110-27-0
EC Number: 203-751-4
MDL number: MFCD00008982
Linear Formula: CH3(CH2)12COOCH(CH3)2
Molecular Formula: C17H34O2


SYNONYMS:
Tetradecanoic acid 1-methylethyl ester, myristic acid and isopropanol ester, IPM, rubbing alcohol, tetradecanoic acid 2-propyl ester, 2-propyl tetradecanoate, DUB IPM, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, component of Sardo Bath Oil, 1405-98-7, ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Isomyst, Bisomel, Promyr, Tetradecanoic acid, 1-methylethyl ester, Deltyl Extra, Kesscomir, Tegester, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Stepan D-50, Emcol-IM, Wickenol 101, Emerest 2314, propan-2-yl tetradecanoate, 1-Methylethyl tetradecanoate, Deltylextra, Myristic acid isopropyl ester, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, FEMA No. 3556, Tetradecanoic acid, isopropyl, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, HSDB 626, NSC 406280, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, tetradecanoic acid 1-methylethyl ester, iso-Propyl N-tetradecanoate, Isopropyl myristate [USAN:NF], DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], MFCD00008982, Deltyextra, Tegosoft M, Liponate IPM, Crodamol 1PM, isopropyl-myristate, Lexol IPM, Crodamol I.P.M, isopropyl myristate, Isopropyltetradecanoate, myristic acid isopropyl, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, MYRISTATE, ISOPROPYL, SCHEMBL2442, Myristic acid-isopropyl ester, Isopropyl myristate, >=98%, CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [INCI], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, LS-2869, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, HY-124190, CS-0085813, FT-0629053, M0481, D02296, F71211, Isopropyl myristate, 1-Methylethyl tetradecanoate, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, Isopropyl myristate, Myristic acid, isopropyl ester, (Tetradecanoic acid, isopropyl, Isopropyl myristate), InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, Propan-2-yl tetradecanoate, Tetradecanoic acid, 1-methylethyl ester, Myristic acid isopropyl ester, IPM, IPM 100, IPM-EX, IPM-R, Isopropyl tetradecanoate, Myristic acid isopropyl ester, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, 1405-98-7, ISOPROPYL MYRISTATE, 110-27-0, Isopropyl tetradecanoate, Estergel, Isomyst, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Promyr, Deltyl Extra, Kesscomir, Tegester, Sinnoester MIP, Crodamol IPM, Plymoutm IPM, Starfol IPM, Unimate IPM, Kessco IPM, Stepan D-50, Emcol-IM, propan-2-yl tetradecanoate, Wickenol 101, Emerest 2314, 1-Methylethyl tetradecanoate, Deltylextra, Myristic acid isopropyl ester, JA-FA IPM, Crodamol I.P.M., Kessco isopropyl myristate, FEMA No. 3556, Tetradecanoic acid, isopropyl, Myristic acid, isopropyl ester, Tetradecanoic acid, isopropyl ester, Caswell No. 511E, HSDB 626, NSC 406280, Isopropyl myristate [USAN], 1-Tridecanecarboxylic acid, isopropyl ester, UNII-0RE8K4LNJS, 0RE8K4LNJS, EINECS 203-751-4, Estergel (TN), EPA Pesticide Chemical Code 000207, NSC-406280, BRN 1781127, methylethyl tetradecanoate, MFCD00008982, iso-Propyl N-tetradecanoate, DTXSID0026838, CHEBI:90027, EC 203-751-4, Tetradecanoic acid methyethyl ester, 1405-98-7, NCGC00164071-01, WE(2:0(1Me)/14:0), MYRISTIC ACID, ISOPROPYL ALCOHOL ESTER, Isopropyl myristate, 98%, TETRADECONOIC ACID, 1-METHYLETHYL ESTER, DTXCID306838, ISOPROPYL MYRISTATE (II), ISOPROPYL MYRISTATE [II], ISOPROPYL MYRISTATE (MART.), ISOPROPYL MYRISTATE [MART.], ISOPROPYL MYRISTATE (USP-RS), ISOPROPYL MYRISTATE [USP-RS], CAS-110-27-0, ISOPROPYL MYRISTATE (EP MONOGRAPH), ISOPROPYL MYRISTATE [EP MONOGRAPH], IPM-EX, IPM-R, tetradecanoic acid 1-methylethyl ester, Deltyextra, Myristic acid-isopropyl ester, Tegosoft M, Isopropyl myristate [USAN:NF], Liponate IPM, Crodamol 1PM, IPM 100, isopropyl-myristate, Lexol IPM, Isopropyltetradecanoate, Radia 7190, Isopropyl myristate (NF), Isopropyl tetradecanoic acid, SCHEMBL2442, Isopropyl myristate, >=98%, CHEMBL207602, ISOPROPYL MYRISTATE [MI], WLN: 13VOY1&1, FEMA 3556, tetradecanoic acid isopropyl ester, ISOPROPYL MYRISTATE [FHFI], ISOPROPYL MYRISTATE [HSDB], ISOPROPYL MYRISTATE [INCI], ISOPROPYL MYRISTATE [VANDF], Isopropyl myristate, >=90% (GC), Tox21_112080, Tox21_202065, Tox21_303171, ISOPROPYL MYRISTATE [WHO-DD], LMFA07010677, NSC406280, s2428, AKOS015902296, Tox21_112080_1, DB13966, USEPA/OPP Pesticide Code: 000207, NCGC00164071-02, NCGC00164071-03, NCGC00256937-01, NCGC00259614-01, LS-14615, HY-124190, CS-0085813, FT-0629053, M0481, NS00006471, D02296, F71211, Isopropyl myristate, 1-Methylethyl tetradecanoate, EN300-25299830, Q416222, SR-01000944751, Isopropyl myristate, Vetec(TM) reagent grade, 98%, Q-201418, SR-01000944751-1, Isopropyl myristate, United States Pharmacopeia (USP) Reference Standard, TETRADECANOIC ACID, ISOPROPYL ESTER (MYRISTATE,ISOPROPYL ESTER), Isopropyl myristate, Pharmaceutical Secondary Standard; Certified Reference Material, InChI=1/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H, Tetradecanoic acid, 1-methylethyl ester, Myristic acid, isopropyl ester, Bisomel, Crodamol I.P.M., Crodamol IPM, Deltyl Extra, Emcol-IM, Isomyst, Isopropyl tetradecanoate, Kessco IPM, Kesscomir, Promyr, Sinnoester MIP, Stepan D-50, Wickenol 101, Emerest 2314, Estergel, Ja-fa IPM, Kessco isopropyl myristate, Plymoutm IPM, Starfol IPM, Tegester, Tetradecanoic acid, isopropyl, Tetradecanoic acid, isopropyl ester, Unimate IPM, 1-Tridecanecarboxylic acid, isopropyl ester, D 50, 1-Methylethyl tetradecanoate, IPM, Lexol IPM, Liponate IPM, Radia 7190, Tegosoft M, iso-Propyl N-tetradecanoate, Methylethyl tetradecanoate, Tetradecanoic acid methyethyl ester, NSC 406280, component of Sardo Bath Oil, 1405-98-7



Isopropyl myristate (IPM) is a clear, light yellow liquid which oily in appearance and vitually odourless.
Isopropyl myristate (IPM) is soluble in most solvents but considered insoluble in water.
Isopropyl myristate (IPM) is manufactured by the esterification of isopropyl alcohol with myristic acid.


Isopropyl myristate (IPM) is soluble in castor oil, cottonseed oil, acetone, benzene, ether, chloroform, ethyl acetate, ethanol, toluene, and mineral oil.
Isopropyl myristate (IPM) dissolves many waxes, cholesterol, lanolin.
Isopropyl myristate (IPM) is practically insoluble in glycerol and propylene glycol.


Isopropyl Myristate (IPM) is a fast spreading emollient suitable for all cosmetic applications.
Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Isopropyl myristate (IPM) is an ester of isopropanol and myristic acid.


Isopropyl myristate (IPM) is manufactured from vegetable oil sources to a minimum 98-percent purity.
Isopropyl myristate (IPM) is an emollient ester of low viscosity; light weight oil.
A non-greasy emollient, Isopropyl myristate (IPM) is readily adsorbed by the skin.


Isopropyl myristate (IPM) is a clear, odorless and non-alcohol solvent and has been demonstrated to be an effective fixative for many odourants: one of a very small number of odourless fixative.
Isopropyl myristate (IPM) is known for promoting the absorption of medicines and other products through the skin.


Isopropyl myristate (IPM) is mobile, non-flammable, and non-sticky.
Isopropyl myristate (IPM) in cosmetics has become universal.
Isopropyl Myristate (IPM) is best stored in sealed containers kept in a cool, dry place.


Isopropyl Myristate (IPM) is prolonged storage, at temperatures above 90°F (32°C) should be avoided.
Isopropyl Myristate (IPM) is a fatty acid ester.
Isopropyl myristate (IPM)'s skin feel, its dry emollience, its skin penetration and clear miscibility with vegetable and mineral oils are just some of the sought after formulation properties.


Isopropyl myristate (IPM) is commonly found in formulations to help reduce the greasiness of whipped butters and emulsions.
Isopropyl Myristate (IPM) can be used in some of the most demanding industrial applications and has been manufactured to the highest standards of eco-friendly management.


A colorless liquid with a faint odor, Isopropyl Myristate (IPM) is used in many applications, including pharma, food and personal care product manufacturing.
Isopropyl Myristate (IPM) is a polar emollient.


Isopropyl Myristate (IPM) is a synthetic oil composed of isopropyl alcohol, a propane derivative, and myristic acid, a naturally occurring fatty acid.
Isopropyl Myristate (IPM)'s a common cosmetic component in a wide range of beauty products, including aftershaves, antiperspirants, and anti-ageing lotions.
Isopropyl myristate (IPM) is not soluble in water, but it is soluble in castor and several other oils.


Isopropyl myristate (IPM) is a slightly yellowish, transparent-looking liquid.
Isopropyl myristate (IPM) is soluble in oil-based solvents and some organic compounds.
Isopropyl Myristate (IPM) is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.


Isopropyl Myristate (IPM) has been largely studied and impulsed as a skin penetration enhancer.
At the moment the primary usage for which Isopropyl Myristate (IPM) is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.


Isopropyl myristate (IPM) has the potential to soften and smooth the skin.
Isopropyl myristate (IPM) helps moisturize the skin.
Isopropyl myristate (IPM) supports the protection of the skin against environmental factors.


Isopropyl Myristate (IPM) is a multifunctional (emollient, solvent, spreading agent, penetrant) synthetically produced ester of vegetal myristic acid and petrochemical isopropyl alcohol that conforms to the requirements of the National Formulary monograph for Isopropyl Myristate.
Isopropyl Myristate (IPM) is non-occlusive, spreads well and provides an elegant, non-oily skin feel.


Isopropyl Myristate (IPM) is a natural product found in Solanum tuberosum, Siraitia grosvenorii, and other organisms with data available.
Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Isopropyl Myristate (IPM) is a slightly yellowish, transparent-looking liquid.


Isopropyl Myristate (IPM) helps gives a silky smooth and velvet texture when making cosmetics such as personal skin care products.
Isopropyl Myristate (IPM) is a virtually odourless solvent.
Isopropyl Myristate (IPM) is known for promoting the absorption of medicines and other products through the skin.


Isopropyl Myristate (IPM) is commonly found in creams, lotions and topical medicines.
In cosmetics, Isopropyl Myristate (IPM) is derived from isopropanol and myristic acid (a fatty acid naturally present in coconut and palm oils).
Isopropyl Myristate (IPM) is a very mild emollient that can be used as a carrier oil in a variety of applications.


Isopropyl myristate (IPM) ensures homogeneous mixing of other ingredients and increases the stability of the formulation.
Isopropyl myristate (IPM) is based on oleochemical.
Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.


Isopropyl Myristate (IPM) is soluble in oil-based solvents and some organic compounds.
Isopropyl Myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Isopropyl Myristate (IPM) mainly works as an emollient in cosmetics and personal care products.


Isopropyl Myristate (IPM) has an oily base with low viscosity and adapts well to the skin.
Isopropyl Myristate (IPM) is composed of of isopropyl alcohol and myristic acid, a common, naturally occurring fatty acid.
Isopropyl Myristate (IPM) is used Cosmetic Grade for Soap Making, Fragrances, Shampoo, Creams & Lotion, Makeup & Adhesive Remover, Antiperspirants & Deodorants.


Isopropyl Myristate (IPM) is a colorless, liquid oleochemical derived from esterized Myristic acid and Isopropyl alcohol.
Isopropyl Myristate (IPM) is a common ingredient in cosmetic products, particularly moisturizing personal care products like lotions, creams, or serums.
Isopropyl Myristate (IPM) is an extremely effective emollient and can act as a thickening or lubricating agent.


Isopropyl Myristate (IPM) is unique in that it enhances the penetration of other ingredients in a formulation, allowing for a variety of applications.
Isopropyl Myristate (IPM) carries RSPO-MB Certification, one of four certification levels offered by the RSPO which monitors the trade of sustainably certified and non-sustainably certified palm oil.


Isopropyl Myristate (IPM) is an ester of isopropanol and myristic acid. Isopropyl Myristate (IPM) is also referred to as tetradecanoic acid.
Isopropyl Myristate (IPM) is manufactured from vegetable oil sources to a minimum 98-percent purity.
Isopropyl Myristate (IPM) made from the combination of isopropyl alcohol and the naturally derived fatty acid myristic acid.


Isopropyl Myristate (IPM) provides a soft and silky feel.
Isopropyl Myristate (IPM) absorbs quickly.
Isopropyl Myristate (IPM) is a colorless oil-like liquid.


Isopropyl Myristate (IPM) is not a food grade product.
Isopropyl Myristate (IPM) is produced using isopropyl alcohol and myristic acid via esterification process.
What's more, Isopropyl Myristate (IPM) can even reduce the heavy, greasy feel in products with high oil content.


Isopropyl Myristate (IPM) has low viscosity fluid non-greasy emollient, stable over a wide pH range, compatible with most surfactants, low viscosity and density - high spreadability.
Isopropyl Myristate (IPM) is colorless oil-like liquid with or little odor, water-insoluble, polar emollient and is used in cosmetics where good absorption into the skin is desired, being studied as a skin enhancer, in pet care products, also used as a solvent in perfume materials,


Isopropyl Myristate (IPM) is an ester of isopropanol and vegetable derived myristic acid.
Isopropyl Myristate (IPM) is an ester included in formulas to dramatically reduce the greasy/oily feel.
Isopropyl Myristate (IPM)’s works wonders in formulations like lotion bars for a glidy, smooth non-greasy feel.


Isopropyl Myristate (IPM)'s also fast-spreading meaning that it gives the formula a good, nice slip.
Isopropyl Myristate (IPM) absorbs quickly into the skin and helps other ingredients to penetrate quicker and deeper.
Thanks to all this, Isopropyl Myristate (IPM)'s one of the most commonly used emollients out there.


Isopropyl Myristate (IPM) has no or little odor.
Isopropyl Myristate (IPM) is soluble in Oil.
Isopropyl Myristate (IPM) is not Soluble in Water.


Isopropyl Myristate (IPM) is a colourless, liquid synthetic oleochemical derived from esterized Myristic acid and Isopropyl alcohol.
Isopropyl Myristate (IPM) is an ester of isopropyl alcohol and myristic acid.
Isopropyl Myristate (IPM) is an extremely effective emollient and can act as a thickening or lubricating agent.


Isopropyl Myristate (IPM) is unique in that it enhances the penetration of other ingredients in a formulation, allowing for a variety of applications.
Include Isopropyl Myristate (IPM) in the oil phase of your products; it can be hot or cold processed.
Isopropyl Myristate (IPM) is an ester of isopropanol and vegetable derived myristic acid.



USES and APPLICATIONS of ISOPROPYL MYRISTATE (IPM):
Isopropyl myristate (IPM) can be used in some of the most demanding industrial applications and has been manufactured to the highest standards of eco-friendly management.
Isopropyl myristate (IPM) is also referred to as tetradecanoic acid.


A colorless liquid with a faint odor, Isopropyl myristate (IPM) is used in many applications, including pharma, food and personal care product manufacturing.
Isopropyl myristate (IPM) is used in formulations to help reduce the greasiness of whipped butters and emulsions.


Isopropyl myristate (IPM) is a virtually odourless solvent. Used as a cosmetic emollient and solvent to replace ethanol in non-alcoholic skin-perfumes.
Poor solubility with terpenes, crystals and resinoids but Ok if they are first blended with other materials.
Isopropyl Myristate (IPM) may be used as a carrier for cosmetic and pharmaceutical additives, and is also an excellent solubilizer for lanolin.


Hence Isopropyl Myristate (IPM) finds broad application in topically applied cosmetic and pharmaceutical liquid, cream, lotion, powder and spray products.
Isopropyl Myristate (IPM) is used in Skin Care, Hair Care, Baby Care, Nail Care, Lip Care, Cosmetics, Massage, and Aromatherapy.
Isopropyl Myristate (IPM) is used as a base for your perfumes and dry body oils.


Isopropyl Myristate (IPM) is used up to 99% as a perfume dilutant.
Isopropyl Myristate (IPM) is used in the fragrance world to dilute materials.
Isopropyl myristate (IPM) is used as a solvent in perfumes for oil or wax products like candles, wax melts, massage oils, hair oil etc.


Isopropyl myristate (IPM) is an emollient ester of low viscosity; the product of the reaction of isopropanol with myristic acid (vegetable source).
A non-greasy emollient, Isopropyl myristate (IPM) is readily adsorbed by the skin.
Miscible with most oils, Isopropyl myristate (IPM) imparts a dry, velvety emollience to products.


Isopropyl Myristate (IPM) is used in diffusers.
Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl Myristate (IPM) is also used as a solvent in perfume materials and in the removal process of prosthetic make-up.


Isopropyl Myristate (IPM) is used as a bath oil on its own or with another oil.
Isopropyl Myristate (IPM) is also used as a treatment for head lice.
Isopropyl Myristate (IPM) is also in flea and tick killing products for pets.


Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl Myristate (IPM) is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.
Isopropyl Myristate (IPM) is a fast spreading emollient suitable for all cosmetic applications.


Isopropyl myristate (IPM) is used to reduce the greasiness of lotion bars, whipped butters and emulsions.
Isopropyl myristate (IPM) is resistant to oxidation and will not become rancid.
Isopropyl myristate (IPM) is also an effective diluent for fragrance oils.


Isopropyl Myristate (IPM) has the potential to soften and smooth the skin.
Isopropyl Myristate (IPM) helps moisturize the skin.
Isopropyl Myristate (IPM) supports the protection of the skin against environmental factors.


Isopropyl Myristate (IPM) ensures homogeneous mixing of other ingredients and increases the stability of the formulation.
Isopropyl Myristate (IPM) is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Hydrolysis of the ester from Isopropyl Myristate (IPM) can liberate the acid and the alcohol.


Isopropyl Myristate (IPM) is theorized to be responsible for decreasing of the pH value of formulations.
Isopropyl Myristate (IPM) is an emollient ester of low viscosity; the product of the reaction of isopropanol with myristic acid (vegetable source).
A non-greasy emollient, Isopropyl Myristate (IPM) is readily adsorbed by the skin.


Isopropyl Myristate (IPM) is also an effective diluent for fragrance oil.
In make up Isopropyl Myristate (IPM) is often used as a remover for prosthetic adhesives and Alcohol activated colours.
Isopropyl Myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption the skin is desired.


In make up Isopropyl Myristate (IPM) is often used as a remover for prosthetic adhesives and Alcohol activated colours.
SOLUBILIZER: Isopropyl Myristate (IPM) is used to help solubilize actives such as sunscreens, vitamins and perfumes into a base.
Isopropyl Myristate (IPM) is used as a cosmetic emollient and solvent to replace ethanol in non-alcoholic skin-perfumes.


Miscible with most oils, Isopropyl Myristate (IPM) imparts a dry, velvety emollience to products. Isopropyl Myristate (IPM) is used to reduce the greasiness of lotion bars, whipped butters and emulsions.
Isopropyl Myristate (IPM) is resistant to oxidation and will not become rancid.


Isopropyl myristate (IPM) is the ester of isopropyl alcohol and myristic acid.
Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired.
Isopropyl myristate (IPM) is used in cosmetics and perfumery as it increases the absorption of perfumes etc on the skin.


Isopropyl myristate (IPM) is a polar emollient and is used in cosmetic and topical pharmaceutical preparations where skin absorption is desired.
Poor solubility with terpenes, crystals and resinoids but Ok if they are first blended with other materials.
Isopropyl Myristate (IPM) is used as a solvent in perfumes for oil or wax products like candles, wax melts, massage oils, hair oil etc.


Isopropyl Myristate (IPM) is also used as a thickener, emollient and humectant, solvent, binder and diluent in perfumes and food flavorings.
Isopropyl Myristate (IPM) can also be used to thicken cosmetic preparations.
In higher concentrations Isopropyl Myristate (IPM) can also be used in products such as make-up removers.


Isopropyl Myristate (IPM) is commonly found in products such as: creams, lotions, hand creams, shampoos, shower gels, make-up removers, powders and make-up foundations.
Application rates of Isopropyl Myristate (IPM) is range from 1 to 20%.


In the paint industry, Isopropyl Myristate (IPM) is used as a base and or solvent in the manufacture of writing instruments containing liquid or gel ink.
In medicine, Isopropyl Myristate (IPM) is used in topical pharmaceutical preparations where it is desired to be absorbed into the skin.
Isopropyl myristate (IPM) is also used as a treatment for head lice.


Isopropyl myristate (IPM) is also in flea and tick-killing products for pets.
Isopropyl Myristate (IPM) is also used as a treatment for head lice.
Isopropyl Myristate (IPM) is a very effective remedy for head lice as a non-systemic agent.


Isopropyl Myristate (IPM) works by dissolving the wax covering the exoskeleton of the head lice, causing the insects to die due to dehydration (water loss).
The oil is manufactured by condensing myristic acid with isopropyl alcohol and is colorless and mild in odor.
Isopropyl Myristate (IPM) is often used as a non-pesticide alternative for treating head lice infestations.


The oil destroys the wax layer which insulates the lice and causes death by dehydration.
Isopropyl Myristate (IPM) is also effective at controlling oral bacteria and is used in several mouthwash products.
Isopropyl Myristate (IPM) is used Creams, lotions, hand creams, shampoo, shower gels, makeup removers, powders and foundations.


Isopropyl Myristate (IPM) can be added to formulas as is, add to oil phase.
Common use levels of Isopropyl Myristate (IPM) are lotions and creams 2-5% and bath oils 30-40%.
Isopropyl Myristate (IPM) is used for external use only.


Isopropyl Myristate (IPM) reduces the greasy feel of most oils, tacky feel of some additives, and acts as a dry emollient in cosmetic formulations.
One lesser known property of Isopropyl Myristate (IPM) is its ability to inhibit the growth of oral bacteria.
Isopropyl Myristate (IPM) is used by many manufacturers of oral hygiene products such as mouthwashes.


Isopropyl Myristate (IPM) is used to remove bacteria from the oral cavity as a non-aqueous component of two-phase mouthwashes.
Isopropyl myristate (IPM) is used to remove bacteria from the oral cavity as the non-aqueous component of the two-phase mouthwash product "Dentyl pH".
Isopropyl myristate (IPM) is also used as a solvent in perfume materials, and in the removal process of prosthetic make-up.


Hydrolysis of the ester from Isopropyl myristate (IPM) can liberate the acid and the alcohol.
The acid is theorized to be responsible for decreasing of the pH value of formulations.
Isopropyl myristate (IPM) is widely used in cosmetics.


Isopropyl myristate (IPM) can moisturize and moisturize the skin.
The skin absorbs Isopropyl myristate (IPM) well.
Isopropyl myristate (IPM) can effectively contact the hair follicles in the cortex, penetrate deep into the skin, and integrate the active ingredients in the cosmetics Bring in and give full play to the role of effective ingredients.


Isopropyl myristate (IPM) is a non-fat emollient and is easily absorbed by the skin.
Isopropyl myristate (IPM) is one of the components of the semi-solid matrix and can also be used as a solvent for many substances in topical administration preparations.


In veterinary medicine, Isopropyl Myristate (IPM) can be found in products for pets that kill fleas and ticks.
Isopropyl Myristate (IPM) can also be found in ear cleaning products to dissolve wax build-up without drying out the skin of the animal's ear.
Isopropyl Myristate (IPM) is commonly used as a lightweight emollient and is often added to body products to reduce the greasy feel left on the skin from some ingredients.


Cosmetic formulations of Isopropyl Myristate (IPM): binding, fragrance, perfuming, emollient
Industrial uses of Isopropyl Myristate (IPM): manufacturer of washing and cleaning products, lubricants and greases, textile treatment products and dyes, polymers, adhesives, sealants, polishes and waxes.


Considered a dry emollient, Isopropyl Myristate (IPM) is primarily used to reduce the greasy feel of other oils and butters in skin care products such as lotions, creams and lotion bars.
Isopropyl Myristate (IPM) also aids in absorption, helping bring other ingredients deeper into the skin.


Common usage of Isopropyl Myristate (IPM) up to 10% added into your oil phase.
Isopropyl Myristate (IPM) is used formulations with large amounts of butters that are infamous for a heavier skin feel.
Try Isopropyl Myristate (IPM) in your whipped butters to reduce the heavy greasy feel.


Isopropyl Myristate (IPM) can be used as a carrier oil and also as a diluent for perfume making.
Isopropyl Myristate (IPM) is a synthetic oil widely used in the cosmetics and pharmaceutical industries as a lubricant, emollient, and as a non-toxic alternative for controlling head lice.


Isopropyl myristate (IPM) is used in various topical preparations and cosmetics, including bath oils, cosmetics, hair care products, facial creams, lotions, lip balm, shaving cream, emollients, deodorants, ears Partial suspension, vaginal cream.
Isopropyl Myristate (IPM) works as an emollient, thickening agent, lubricant, and texture enhancer in beauty products.


Isopropyl Myristate (IPM) helps to enhance the penetration of ingredients.
For example, Isopropyl myristate (IPM) is a self-emulsifying ingredient in a cold cream prescription, and this cold cream prescription can be used as a base for many drugs and skin drugs.


Isopropyl Myristate (IPM)'s non-greasy properties make formulas with high oil content feel silky.
Isopropyl Myristate (IPM) is miscible with most oils and a common carrier for fragrance oils.
Isopropyl Myristate (IPM) is favorite ingredient amongst formulators for its versatile application.


Isopropyl myristate (IPM) can be used up to 85% in perfume formulations.
For room sprays, use only up to 15% otherwise Isopropyl myristate (IPM) will be oily, greasy and might make surfaces slippery.
Isopropyl myristate (IPM) is used as a bath oil on its own or with another oil.


Isopropyl myristate (IPM) is used as a reed diffuser base (balance with alcohol to control diffusion).
In creams, lotions and body butters Isopropyl myristate (IPM) can be added for a sliky-soft feeling, sensuous glide when applying to skin.
Use Isopropyl myristate (IPM) at up to 5% in creams, lotions and body butters.


Isopropyl myristate (IPM) is commonly found in creams, lotions and topical medicines.
Isopropyl myristate (IPM) is also used as a thickener, emollient and humectant, solvent, binder and diluent in perfumes and food flavorings.
In cosmetics, Isopropyl myristate (IPM) (also known as rubbing alcohol) is derived from isopropanol and myristic acid (a fatty acid naturally present in coconut and palm oils).


Isopropyl myristate (IPM) is a very mild emollient that can be used as a carrier oil in a variety of applications.
Isopropyl myristate (IPM) is included in formulations to dramatically reduce the sensation of greasiness and/or heaviness; it is excellent in formulations with a high content of butters known for their heavier skin feel (e.g. shea).


Isopropyl myristate (IPM) is also an excellent mild skin softener and can be included in recipes as an alternative to liquid carrier oil for lighter and faster absorption.
Isopropyl myristate (IPM) can also be used to thicken cosmetic preparations.


In higher concentrations Isopropyl myristate (IPM) can also be used in products such as make-up removers.
Isopropyl myristate (IPM) is commonly found in products such as: creams, lotions, hand creams, shampoos, shower gels, make-up removers, powders and make-up foundations.


Application rates of Isopropyl myristate (IPM) range from 1 to 20%.
In the paint industry, Isopropyl myristate (IPM) is used as a base and or solvent in the manufacture of writing instruments containing liquid or gel ink.
In medicine, Isopropyl myristate (IPM) is used in topical pharmaceutical preparations where it is desired to be absorbed into the skin.


Isopropyl myristate (IPM) is also used as a treatment for head lice.
Isopropyl myristate (IPM) is a very effective remedy for head lice as a non-systemic agent.
Isopropyl myristate (IPM) works by dissolving the wax covering the exoskeleton of the head lice, causing the insects to die due to dehydration (water loss).


Isopropyl Myristate (IPM) is a synthetic oil that is used as an emollient and solvent in personal care and cosmetic products.
Isopropyl Myristate (IPM) is a clear, colorless liquid that is miscible with most organic solvents including alcohol and propylene glycol.
In personal care products, Isopropyl Myristate (IPM) is used to dissolve other ingredients, give a smooth, silky feel to the skin and help products spread easily.


Isopropyl Myristate (IPM) is also used as a solvent for fragrances, and other active ingredients in products such as lotions, creams, ointments as well as make-up and hair care products.
Isopropyl Myristate (IPM) is a synthetic oil used as an emollient, thickening agent, or lubricant in beauty products such as aftershaves, shampoos, bath oils, antiperspirants, deodorants, oral hygiene products, and various creams and lotions.


One lesser known property of Isopropyl myristate (IPM) is its ability to inhibit the growth of oral bacteria.
Isopropyl myristate (IPM) is used by many manufacturers of oral hygiene products such as mouthwashes.
Isopropyl myristate (IPM) is used to remove bacteria from the oral cavity as a non-aqueous component of two-phase mouthwashes.


In veterinary medicine, Isopropyl myristate (IPM) can be found in products for pets that kill fleas and ticks.
Isopropyl myristate (IPM) can also be found in ear cleaning products to dissolve wax build-up without drying out the skin of the animal's ear.
Cosmetic Uses of Isopropyl myristate (IPM): binding agent, perfuming agents, skin conditioning, skin conditioning - emollient, and solvents


-Isopropyl myristate (IPM) is used as adhesive, emollient and keratin softener in cosmetics.
Products with this ingredient are easier to apply and have a refreshing texture.
The component has small molecules, is easy to penetrate, and has a good cleaning effect for makeup remover.


-Solvent uses of Isopropyl myristate (IPM):
Isopropyl myristate (IPM) plays a key role in the dissolution of lanolin.
Mixtures containing up to 50 % lanolin in Isopropyl myristate (IPM) remain stable non-viscous liquids at room temperature.

The oil is therefore used as a solvent and penetrant in anhydrous skin lotions with high lanolin content.
Isopropyl myristate (IPM) is used as a solvent for varnishes and paints, since the formulations used in the manufacture of paints and varnishes consist of many different organic substances.


-Isopropyl myristate (IPM) can be used as a penetration enhancer in transdermal absorption preparations, and can be used in combination with therapeutic ultrasound and iontophoresis.
Isopropyl myristate (IPM) can be used as the main component of the oil phase in water-oil gel prolonged-release emulsion.

Isopropyl myristate (IPM) is a fast spreading emollient suitable for all cosmetic applications.
Isopropyl myristate (IPM) acts as an emulsifier, humectant, emollient, perfuming-, binding and masking agent.
Isopropyl myristate (IPM) is used in perfume and fragrance actives.



PHARMACODYNAMICS OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is an emollient vehicle that is effective at enhancing the penetration of other medical agents that may be incorporated into the vehicle as active agents.
In one study, a 50:50 isopropanol-Isopropyl Myristate (IPM)e binary enhancer synergistically increased the transport of estradiol across a two-layer human epidermis in vitro.



MECHANISM OF ACTION OF ISOPROPYL MYRISTATE (IPM):
As a pediculicide, Isopropyl Myristate (IPM) is capable of physically coating the exoskeleton bodies of lice.
This physical coating subsequently immobilizes the lice and works to dissolve the wax covering on the insect exoskeleton and blocks the insects' airways, leading to death by dehydration.

Although this physical action of Isopropyl Myristate (IPM) results in little lice resistance (given the lack of immunologic or chemical activity in this mechanism of action), the substance is also not ovicidal, which means any eggs that may have been laid by lice would not be affected. Moreover, Isopropyl Myristate (IPM) is capable of eliciting its pediculicide action in a contact time of only 10 minutes per each necessary administration 8,9,3,4.




ALTERNATIVES OF ISOPROPYL MYRISTATE (IPM):
*C1215 ALKYL BENZOATE,
*COCOCAPRYLATE,
*ISODODECANE



KEY PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
*Water insoluble
*Clear, colourless, oil-like
*Good skin absorption in moisturisers
*Emollient
*Halal
*Kosher
*Non-GMO
*RSPO MB available



MAIN FUNCTIONS OF ISOPROPYL MYRISTATE (IPM):
*Binding agent :
Isopropyl myristate (IPM) allows different cosmetic ingredients to adhere together.
*Emollient :
Isopropyl myristate (IPM) softens and smooths the skin
*Masking :
Reduces or suppresses the odor or main flavor of the product
*Fragrance:
Isopropyl myristate (IPM) is used in the manufacture of perfumes and aromatic raw materials
Percentage of ingredients of natural origin according to ISO 16128: 78 %.



BENEFITS AND APPLICATIONS OF ISOPROPYL MYRISTATE (IPM):
*The use of isopropyl myristate in skincare products has the advantage of assisting in the dissolution of other skincare components, enabling them to be dispersed uniformly throughout the formulation.

*Isopropyl Myristate (IPM) is especially beneficial for dry and flaky skin as it acts as a brilliant emollient and helps in softening and smoothing your skin.

*Isopropyl Myristate (IPM) also eliminates germs, which is one of its key advantages.
As a result, Isopropyl Myristate (IPM) is frequently used in hand sanitizers.
This, together with the fact that Isopropyl Myristate (IPM) evaporates quickly, makes it an excellent component in both skincare and hand sanitizer products.

*Isopropyl Myristate (IPM) works as an emollient for your DIY formulation, which increases the product’s spreadability and improves texture.
Isopropyl Myristate (IPM) is special in that it can improve the penetration of other substances.

*Isopropyl Myristate (IPM) is incredibly necessary when formulating and making cosmetically elegant goods.



HOW ISOPROPYL MYRISTATE (IPM) WORKS?
Isopropyl Myristate (IPM) works by attracting moisture from the air and fixing it in the deep layers of skin and scalp.
Isopropyl Myristate (IPM) works by creating a preventive barrier that locks moisture into the skin and increases the moisture retention capacity.



CONCENTRATION AND SOLUBILITY OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is recommended that it should be used at a concentration of 1 to 20%.
Isopropyl Myristate (IPM) is soluble in most solvents but is insoluble in water.



HOW TO USE ISOPROPYL MYRISTATE (IPM):
Prepare the oil and water phases of your formulation separately.
Heat the water and oil phase using a double boiler.
Add Isopropyl Myristate (IPM) to the heated oil phase with constant stirring.
Blend both the phases using a mini-mixer until the required consistency is not obtained.



ORIGIN OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is commercially produced by distillation, before which the esterification of myristic acid and isopropanol is carried out, and the resulting alkali is refined to neutralize the catalyst, and the product is then distilled to obtain isopropyl myristate.



WHAT DOES ISOPROPYL MYRISTATE (IPM) DO IN A FORMULATION?
*Emollient
*Perfuming
*Skin conditioning
*Viscosity controlling



SAFETY PROFILE OF ISOPROPYL MYRISTATE (IPM):
Isopropyl Myristate (IPM) is determined safe for use in cosmetics according to the Cosmetics Ingredient Review (CIR) panel.



MAIN FUNCTIONS OF ISOPROPYL MYRISTATE (IPM):
*Binding agent :
Isopropyl Myristate (IPM) allows different cosmetic ingredients to adhere together.

*Emollient :
Isopropyl Myristate (IPM) softens and smooths the skin

*Masking :
Isopropyl Myristate (IPM) reduces or suppresses the odor or main flavor of the product

*Fragrance:
Isopropyl Myristate (IPM) is used in the manufacture of perfumes and aromatic raw materials
Percentage of ingredients of natural origin according to ISO 16128: 78 %.



BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Superior emollient for non-greasy bath, body and baby oils
*Lubricant and compression aid for pressed powders
*Light & non-tacky emollient for creams and lotions. Readily adsorbed by the skin
*When used at high concentrations it gently lifts makeup and surface dirt
*Gives gloss and shine to hair
*Resistant to oxidation (does not become rancid)
*Widely used as diluent for fragrance oils.



FEATURES & BENEFITS OF ISOPROPYL MYRISTATE (IPM):
*Biodegradable
*Emollient
*80% reduction in VOCs compared with Texanol: meets and exceeds international regulations for no VOCs
*Fragrance Extender
*Lubricant
*Nonocclusive
*Nonoily
*Plant Derived / Vegetal Based
*Spreading Agent
*USP / NF Grade



WHY PEOPLE USE ISOPROPYL MYRISTATE (IPM):
To provide emollient properties to products.



POPULAR PRODUCTS THAT USE ISOPROPYL MYRISTATE (IPM):
*Lotions.
*Creams.



INTERESTING FACTS OF ISOPROPYL MYRISTATE (IPM):
*Emollient (softens skin).
*Counteracts the “oily” feel in some lotions.
*Provides a soft and silky feel.
*Absorbs quickly.



PROPERTIES OF ISOPROPYL MYRISTATE (IPM):
Cosmetic and pharmaceutical uses of Isopropyl Myristate (IPM): Oil base with low viscosity, good adaptation to skin.
Isopropyl Myristate (IPM) is a colorless no odor.
Isopropyl Myristate (IPM) is suitable for cream-milk lotion, emollient and shampoo.



PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL MYRISTATE (IPM):
Cas No: 110-27-0
EINECS No: 203-751-4
Molecular formula: CH3(CH2)12COOC­H(CH3)2
Appearance: Light yellow / clear oily liquid
Other names: Tetradecanoic acid, 1-methylethyl ester;
Myristic acid isopropyl ester: IPM;
propan-2-yl tetradecanoate; Estergel;
Molecular weight: 270.46
Acid value: 0.5 max
Specific gravity: 0.85
Melting Point: 3-5 oC
Boiling Point: 167 oC
Flash Point: 152 oC
Heavy metal: 0.0005% max
Insoluble in: Water.
Soluble in: Most organic solvents
Refractive index: 1.44
Vapour pressure: 9.35X10-5 mm Hg at 25 C

Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Chemical formula: C17H34O2

Molar mass: 270.457 g·mol−1
Density: 0.85 g/cm3
Boiling point: 167 °C (333 °F; 440 K) at 9 mmHg
CAS number: 110-27-0
EC number: 203-751-4
Hill Formula: C₁₇H₃₄O₂
Molar Mass: 270.45 g/mol
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)
Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility: Boiling Point: 192-193°C
Melting Point: 2-3°C

Solubility: Soluble in benzyl benzoate, ethyl lactate, paraffin oil
Insoluble in water
Physical state: liquid
Color: No data available
Odor: No data available
Melting point/freezing point:
Melting point/range: 3 °C - lit.
Initial boiling point and boiling range: 193 °C at 27 hPa - lit.
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point > 150 °C - open cup
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available

Water solubility: No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available
Density: 0,85 g/cm3 at 25 °C - lit.
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Acid Value (mg KOH/g): 0.5 Max
Saponification Value (mg KOH/g): 206-211
Color (APHA): 30 Max
Moisture Content (%): 0.1 Max

Ash Content (%): 0.1 Max
Peroxide Value (meq/Kg): 0.6 Max
Viscosity (mPa.s) 20℃: 5-6
Density (g/cm3) 20℃: 0.852-0.855
Refractive Index 20℃: 1.434-1.437
APPEARANCE AT 20°: Clear mobile liquid / solid
COLOR: Colorless
ODOR: Nearly odorless, oily, fatty
OPTICAL ROTATION (°): 0 / 0
DENSITY AT 20°C (G/ML)): 0,848 - 0,856
REFRACTIVE INDEX ND20: 1,4320 - 1,4370
FLASHPOINT (°C): 155
SOLUBILITY: Insoluble in water
ASSAY (% GC): > 98
ACID VALUE (MG KOH/G): < 0,5
Appearance: A colorless or slightly yellow oily liquid
Ester content %: ≥98
Acid value(mg KOH/g): ≤0.5

Hazen(Color): ≤30
Refractive index: 1.434-1.438
Specific gravity(20℃): 0.850-0.855
Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.
Pounds per Gallon - (est).: 6.990 to 7.156
Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure: 0.000329 mmHg @ 25.00 °C. (est)

Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 7.253 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers,
protected from heat and light.
Soluble in: amyris wood oil,
benzyl benzoate, benzyl salicylate,
clove leaf oil, deluent for candle fragrances,
ethyl acetoacetate, ethyl lactate,
paraffin oil, water, 0.01354 mg/L @ 25 °C (est),
Insoluble in: water,
Similar Items:note
isoamyl myristate, butyl myristate, isobutyl myristate,
ethyl myristate, hexyl myristate
Boiling point: 140 °C (3 hPa)
Density: 0.85 g/cm3 (20 °C)

Flash point: >150 °C
Ignition temperature: >300 °C
Vapor pressure: Solubility: IUPAC Name: propan-2-yl tetradecanoate
Molecular Weight: 270.45
Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChI: InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
Boiling Point: 167 °C at 9 mmHg
Melting Point: -5ºC
Flash Point: 29.6 dyne/cm Density: 0.864 g/cm³
Purity: 98%+
Density: 0.853 g/cm3

Solubility: Soluble in chloroform (slightly), ethyl acetate (slightly).
Appearance: Clear colorless oil
Storage: Room Temperature
EINECS: 203-751-4
Hazard Class: 6.1
Hazard Codes: Xi
HS Code: 29159080
Log P: 5.63910
MDL: MFCD00008982
PSA: 26.3
Refractive Index: 1.434-1.436
Risk Statements: R36/37/38
RTECS: XB8600000
Safety Statements: S26-S36
Stability: Stable.
Vapor Pressure: 0.000329mmHg at 25°C
Molecular Weight: 270.5 g/mol
XLogP3-AA: 7.2

Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 14
Exact Mass: 270.255880323 g/mol
Monoisotopic Mass: 270.255880323 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Coun: 19
Formal Charge: 0
Complexity: 199
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Appearance: colorless clear oily liquid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity: 0.84000 to 0.86000 @ 25.00 °C.
Pounds per Gallon - (est).: 6.990 to 7.156
Refractive Index: 1.42800 to 1.44300 @ 20.00 °C.
Melting Point: 2.00 to 3.00 °C. @ 760.00 mm Hg
Boiling Point: 192.00 to 193.00 °C. @ 20.00 mm Hg
Acid Value: 1.00 max. KOH/g
Saponification Value: 207.00
Vapor Pressure: 0.000329 mmHg @ 25.00 °C. (est)
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 7.253 (est)
Shelf Life: 24.00 month(s) or longer if stored properly.
Storage: store in cool, dry place in tightly sealed containers, protected from heat and light.

Soluble in: amyris wood oilbenzyl benzoatebenzyl salicylate
clove leaf oil
deluent for candle fragrances
ethyl acetoacetate
ethyl lactate
paraffin oil
water, 0.01354 mg/L @ 25 °C (est)
Insoluble in:
water
IUPAC: Propan-2-yl tetradecanoate
INCI: ISOPROPYL MYRISTATE
CAS: 110-27-0
Molar mass: 270,457 g/mol
Density: 0,85 g/cm3 (20 °C)
Solubility: Miscible with water, benzene, chloroform, ethanol, ether, glycerin.
Soluble in acetone.



FIRST AID MEASURES of ISOPROPYL MYRISTATE (IPM):
-Description of first-aid measures:
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most).
Consult doctor if feeling unwell.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOPROPYL MYRISTATE (IPM):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions
Take up with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ISOPROPYL MYRISTATE (IPM):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Advice for firefighters:
In the event of fire, wear self-contained breathing apparatus
-Further information:
none



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL MYRISTATE (IPM):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 30 min
*Respiratory protection:
Not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ISOPROPYL MYRISTATE (IPM):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.



STABILITY and REACTIVITY of ISOPROPYL MYRISTATE (IPM):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available


ISOPROPYL MYRISTATE (MASESTER E1140)

Isopropyl myristate (Masester E1140) is a chemical compound commonly used in various industries, especially in the cosmetic and pharmaceutical sectors.
Isopropyl myristate (Masester E1140) is an ester derived from isopropyl alcohol and myristic acid, which is a fatty acid found in palm oil and coconut oil.
The chemical formula for isopropyl myristate is C17H34O2.

CAS Number: 110-27-0.
EC Number: 271-820-6

IPM, 1-Methylpropyl myristate, Myristic acid isopropyl ester, Isopropyl ester of myristic acid, Tetradecanoic acid isopropyl ester, Isopropyl tetradecanoate, Myristyl isopropyl ester, ISO myristate, Myristic acid 1-methylpropyl ester, Isopropyl myristoleate, IPMO, Myristic acid iso-propyl ester, 1-Methylpropyl tetradecanoate, Iso-propyl tetradecanoate, Tetradecanoic acid 1-methylpropyl ester, Eutanol G, Isopropyl ester of tetradecanoic acid, Palatinol A, Crodamol IPM, Hexalube MPA, Myristol 318, Isopropyl myristate synthetic, Neodol 25 isomer, Stepanthex IPM, Estol 1514, Ethyl myristate, Isomyst, Loxanol V, Witconol APM, Arlamol IPM, Isofol E, Crodamol IPM, Witconol APM-S, Estol 1514S, Palmester 1514, Palmsorb IPM, Dow Corning 556 Cosmetic Grade Fluid, Myritol 312, Silube IPM, Abil WE 09, Lanol 1314, Myritol 318, Silub Eutanol, Witconol APM-S (PM), Crodamol DA, Empilan IPM, Myritol 322, Teracol IPM, Silub Eutanol, Eumatex IPM, Stepantex IPM-S, Super Refined Isopropyl Myristate, Crodamol IPP, Suprmol IPP, Empilan IPM-NF, Isofol-M, Eumatex IPM-R, Isohexadecyl myristate, Myristic acid, 1-methylpropyl ester, Sorbester



APPLICATIONS


Isopropyl myristate (Masester E1140) is commonly used in skincare formulations such as lotions and creams, contributing to a smooth and luxurious feel upon application.
Isopropyl myristate (Masester E1140) is a key ingredient in sunscreens, providing an even spread and enhancing the effectiveness of UV filters.
In the cosmetic industry, Isopropyl myristate is utilized in foundations and concealers to improve their texture and blendability.

Isopropyl myristate (Masester E1140) finds application in makeup removers, aiding in the gentle removal of cosmetic products without causing skin irritation.
Isopropyl myristate (Masester E1140) is employed in the formulation of perfumes and colognes, enhancing the diffusion and longevity of fragrances.
Due to its skin-penetrating properties, it is used in topical pharmaceutical formulations to improve the absorption of medicinal agents.
In hair care products such as conditioners and detanglers, Isopropyl myristate contributes to a silky and manageable hair texture.

Isopropyl myristate (Masester E1140) is found in bath oils, adding a luxurious touch to bathing experiences and leaving the skin feeling soft and moisturized.
Isopropyl myristate (Masester E1140) is used in the production of massage oils, ensuring smooth gliding during massages and promoting skin hydration.
In the creation of transparent and long-lasting emulsions, it aids in stabilizing the formulation and ensuring uniform distribution of active ingredients.

Isopropyl myristate (Masester E1140) is employed in the development of water-resistant cosmetic products, including foundations and mascaras.
Isopropyl myristate (Masester E1140) is included in the formulation of body lotions, providing a non-greasy and lightweight texture.
Isopropyl myristate (Masester E1140) finds application in lip balms and glosses, improving the spreadability and overall feel on the lips.

Isopropyl myristate (Masester E1140) is utilized in the creation of customized skincare products, offering versatility in formulations.
Due to its compatibility with various cosmetic ingredients, it is a preferred choice for multifunctional skincare serums.
Isopropyl myristate (Masester E1140) is used in the manufacturing of bath salts, contributing to their texture and skin-conditioning properties.
Isopropyl myristate (Masester E1140) is employed in the creation of clear and stable essential oil blends for aromatherapy applications.
In the fragrance industry, it is added to scented candles to enhance the release of fragrance during burning.

Isopropyl myristate (Masester E1140) is utilized in the production of water-resistant sunless tanning products, ensuring an even and natural-looking tan.
Isopropyl myristate (Masester E1140) is incorporated into the formulation of BB creams, providing a smooth and blendable texture.

Isopropyl myristate (Masester E1140) is found in anti-aging creams and serums, contributing to the overall sensory experience and effectiveness of the products.
Isopropyl myristate (Masester E1140) is used in the formulation of clear and water-resistant eyebrow products, ensuring long-lasting results.
In the creation of body mists, it adds a refreshing and hydrating element to the formulation.

Isopropyl myristate (Masester E1140) is included in the development of facial primers, improving the adherence and longevity of makeup.
Isopropyl myristate (Masester E1140) continues to find applications in various cosmetic and personal care products, showcasing its versatility in enhancing product performance and user experience.

Isopropyl myristate (Masester E1140) is utilized in the formulation of water-resistant and long-lasting eyeshadows, ensuring vibrant and crease-resistant eye makeup.
Isopropyl myristate (Masester E1140) is incorporated into clear and water-resistant facial cleansers, aiding in the gentle removal of makeup and impurities from the skin.

Isopropyl myristate (Masester E1140) is a common ingredient in cuticle balms, contributing to their non-greasy and moisturizing properties.
Isopropyl myristate (Masester E1140) finds application in the production of clear and water-resistant blush sticks, providing a natural and blendable flush to the cheeks.
In the development of clear and non-comedogenic dry shampoo sprays, Isopropyl myristate helps in refreshing and volumizing the hair between washes.

Isopropyl myristate (Masester E1140) is utilized in the formulation of clear and lightweight shaving oils, promoting a smooth and comfortable shaving experience.
Isopropyl myristate (Masester E1140) is included in water-resistant body powders, ensuring a silky and mattifying finish on the skin.

Isopropyl myristate (Masester E1140) is employed in the creation of clear and water-resistant body shimmer oils, offering a subtle and radiant glow to the skin.
In the production of clear and water-resistant body lotions for humid conditions, it provides long-lasting hydration without a heavy feel.

Isopropyl myristate (Masester E1140) is found in the formulation of clear and water-resistant lip tints, offering a natural and tinted lip color.
Isopropyl myristate (Masester E1140) is used in the development of clear and water-resistant mascara primers, enhancing lash volume and definition.
Isopropyl myristate (Masester E1140) contributes to the creation of clear and non-greasy facial primers, providing a smooth base for makeup application.

Isopropyl myristate (Masester E1140) is incorporated into the formulation of clear and water-resistant lip scrubs, offering gentle exfoliation and hydration.
In the production of clear and water-resistant essential oil roll-ons, it ensures easy and smooth application for aromatherapy purposes.

Isopropyl myristate (Masester E1140) is employed in clear and non-greasy hand sanitizers, providing a pleasant and effective sanitizing experience.
Isopropyl myristate (Masester E1140) is utilized in the creation of clear and water-resistant perfume oils, enhancing the longevity of fragrance.

Isopropyl myristate (Masester E1140) is found in the composition of clear and water-resistant skincare sticks, such as blemish treatments and spot correctors.
Isopropyl myristate (Masester E1140) is incorporated into the formulation of clear and water-resistant eyebrow gels, ensuring defined and long-lasting brows.
Isopropyl myristate (Masester E1140) is used in the development of clear and water-resistant body serums, providing targeted skincare benefits.
In the creation of clear and lightweight body mists, it adds a refreshing and hydrating element to the overall fragrance.

Isopropyl myristate (Masester E1140) is employed in clear and water-resistant deodorant formulations, ensuring long-lasting freshness.
Isopropyl myristate is found in the production of clear and non-greasy cuticle oils, promoting healthy and moisturized nails.

Isopropyl myristate (Masester E1140) is used in the formulation of clear and water-resistant tattoo balms, enhancing the vibrancy and longevity of tattoos.
Isopropyl myristate (Masester E1140) contributes to the creation of clear and water-resistant body creams, providing intensive hydration without a heavy residue.
Isopropyl myristate (Masester E1140) continues to be a versatile ingredient, adapting to various formulations in the cosmetic and personal care industry, showcasing its adaptability and value in enhancing product performance.

Isopropyl myristate (Masester E1140) is utilized in the formulation of clear and water-resistant facial cleansers, providing effective makeup removal and skin cleansing.
Isopropyl myristate (Masester E1140) is found in the composition of clear and non-greasy makeup setting sprays, aiding in the longevity of makeup throughout the day.
In the development of clear and water-resistant hair serums, Isopropyl myristate contributes to frizz control and hair shine.

Isopropyl myristate (Masester E1140) is incorporated into the formulation of clear and lightweight body scrubs, offering gentle exfoliation and skin renewal.
Isopropyl myristate is employed in the creation of clear and water-resistant lip balms, providing nourishment and hydration to the lips.

Isopropyl myristate (Masester E1140) is used in the production of clear and water-resistant foundation formulations, ensuring a smooth and even complexion.
Isopropyl myristate (Masester E1140) contributes to the creation of clear and non-greasy aftershave lotions, promoting soothing and moisturizing effects on the skin.
Isopropyl myristate (Masester E1140) is found in the formulation of clear and water-resistant hand creams, providing hydration without a sticky feel.

In the composition of clear and water-resistant body washes, it enhances the lathering and cleansing properties.
Isopropyl myristate (Masester E1140) is incorporated into clear and non-comedogenic facial moisturizers, offering lightweight hydration for various skin types.

Isopropyl myristate (Masester E1140) is utilized in the creation of clear and water-resistant body powders, providing a silky and mattifying finish.
Isopropyl myristate (Masester E1140) is employed in the formulation of clear and water-resistant concealer sticks, ensuring seamless coverage and long wear.
In the development of clear and non-greasy hair masks, Isopropyl myristate aids in conditioning and detangling.

Isopropyl myristate (Masester E1140) contributes to the creation of clear and water-resistant body oils, offering a nourishing and aromatic experience.
Isopropyl myristate (Masester E1140) is used in the production of clear and water-resistant facial mists, providing a refreshing and hydrating boost.

In the formulation of clear and non-greasy tattoo aftercare balms, it promotes skin healing and color preservation.
Isopropyl myristate (Masester E1140) is incorporated into the creation of clear and water-resistant lip glosses, enhancing shine and glossiness.

Isopropyl myristate (Masester E1140) is found in the composition of clear and water-resistant body butter formulations, offering deep moisturization.
Isopropyl myristate (Masester E1140) is utilized in the development of clear and non-greasy cuticle creams, promoting healthy and well-nourished nails.

Isopropyl myristate (Masester E1140) contributes to the creation of clear and water-resistant hair styling gels, providing hold and manageability.
Isopropyl myristate (Masester E1140) is employed in the formulation of clear and water-resistant eyebrow pencils, ensuring precise application.
In the creation of clear and non-comedogenic sunscreen lotions, it enhances the spreadability and UV protection.

Isopropyl myristate (Masester E1140) is incorporated into the production of clear and water-resistant face masks, offering skincare benefits without residue.
Isopropyl myristate (Masester E1140) is used in the formulation of clear and water-resistant lip liners, providing defined and long-lasting lip contours.
In the development of clear and non-greasy foot creams, it promotes moisturization and softening for smoother feet.



DESCRIPTION


Isopropyl myristate (Masester E1140) is a chemical compound commonly used in various industries, especially in the cosmetic and pharmaceutical sectors.
Isopropyl myristate (Masester E1140) is an ester derived from isopropyl alcohol and myristic acid, which is a fatty acid found in palm oil and coconut oil.
The chemical formula for isopropyl myristate is C17H34O2.

Isopropyl myristate, commonly known as IPM, is a clear and colorless liquid with a faint, mild odor.
Isopropyl myristate (Masester E1140) is valued for its light texture, providing a smooth and non-greasy feel in cosmetic formulations.
Isopropyl myristate (Masester E1140) is derived from the esterification of isopropyl alcohol and myristic acid, a fatty acid found in natural sources like palm and coconut oil.

Due to its excellent solubility in various organic solvents, it is often chosen as an ingredient for oil-based cosmetic and pharmaceutical products.
Isopropyl myristate (Masester E1140) acts as an emollient, effectively softening and soothing the skin upon application.

With its unique skin-penetrating properties, Isopropyl myristate aids in the absorption of other active ingredients, enhancing the efficacy of skincare formulations.
Used widely in sunscreens, lotions, and creams, it contributes to the luxurious feel and spreadability of these products.
Isopropyl myristate (Masester E1140) is a common ingredient in fragrance formulations, improving the diffusion and longevity of scents in perfumes.

In hair care products like conditioners, it imparts a silky texture, making hair more manageable.
Isopropyl myristate (Masester E1140) is employed in pharmaceuticals for topical formulations and drug delivery systems where enhanced skin penetration is desirable.
Known by trade names like Crodamol IPM and Arlamol IPM, it is a staple in the cosmetic industry for its versatility.

Isopropyl myristate (Masester E1140) serves as a lubricant in formulations, ensuring ease of application and a pleasant sensory experience.
In the creation of body lotions, it contributes to a non-sticky and lightweight feel on the skin.
Isopropyl myristate (Masester E1140) is commonly found in makeup products, including foundations and lipsticks, improving their texture and application.

Isopropyl myristate (Masester E1140) is valued for its stability, providing a longer shelf life to various cosmetic and personal care formulations.
Used in bath oils, it adds a silky touch to bath products, enhancing the overall bathing experience.
Employed in the creation of massage oils, it aids in smooth gliding during massages, leaving the skin soft and moisturized.

Isopropyl myristate (Masester E1140) is a key ingredient in many skincare serums, contributing to their easy absorption and lightweight texture.
Known for its non-comedogenic nature, it is suitable for formulations targeting individuals with sensitive or acne-prone skin.
Isopropyl myristate (Masester E1140)is utilized in the development of clear and water-resistant cosmetic products, ensuring their longevity.
Isopropyl myristate (Masester E1140) is often chosen for its ability to improve the spreadability of lip balms and glosses.

In the formulation of sunless tanning products, it aids in achieving an even and natural-looking tan.
Due to its compatibility with various cosmetic ingredients, it is a preferred choice for customizable skincare formulations.

Isopropyl myristate (Masester E1140) plays a role in the creation of transparent and long-lasting emulsions, ensuring uniform distribution of ingredients.
Renowned for its multifunctional properties, Isopropyl myristate continues to be a sought-after ingredient in the ever-evolving landscape of cosmetic and personal care products.



PROPERTIES


Chemical Formula: C17H34O2
Molecular Weight: Approximately 270.45 g/mol
Physical State: Liquid
Color: Clear
Odor: Mild
Solubility:
Soluble in most organic solvents.
Insoluble in water.
Density: 0.852 g/cm³ at 20°C
Boiling Point: Approximately 270°C (518°F)
Melting Point/Freezing Point: Below 0°C (32°F)
Flash Point: >100°C (212°F) (Closed cup)
pH: Not applicable (not typically measured for non-aqueous liquids)
Partition Coefficient (n-Octanol/Water): Not available
Viscosity: Not specified (depends on temperature and concentration)
Refractive Index: Not specified
Surface Tension: Not specified
Vapor Pressure: Not specified
Vapor Density: Not specified
Flammability: Non-flammable
Autoignition Temperature: Not available
Hydrolysis: Stable under normal conditions
Compatibility: Compatible with various cosmetic and pharmaceutical ingredients.



FIRST AID


Inhalation:
If inhaled, move the affected person to fresh air.
If respiratory irritation or difficulties persist, seek medical attention.

Skin Contact:
In case of skin contact, remove contaminated clothing and wash the affected area with plenty of soap and water.
If irritation or redness persists, seek medical attention.

Eye Contact:
If Isopropyl myristate comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention if irritation or redness persists.

Ingestion:
If ingested accidentally, do not induce vomiting unless directed by medical personnel.
Rinse the mouth with water and seek immediate medical attention.
Never give anything by mouth to an unconscious person.

Note:
If symptoms persist or if there is uncertainty about the severity of exposure, seek medical attention promptly.
Provide medical personnel with information about the product, its concentration, and the circumstances of exposure.



HANDLING AND STORAGE


Handling:

Personal Protection:
Wear appropriate personal protective equipment (PPE) such as gloves and safety goggles when handling Isopropyl myristate to prevent skin and eye contact.
Use protective clothing as necessary to minimize contact with skin.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to control airborne concentrations.
Avoid inhalation of vapors or mists.
Use respiratory protection if necessary.

Avoidance:
Avoid contact with eyes, skin, and clothing.
Do not ingest Isopropyl myristate.

Hygiene Practices:
Wash hands thoroughly after handling.
Launder contaminated clothing before reuse.

Spill and Leak Procedures:
In the event of a spill, contain the spill and absorb with appropriate absorbent materials.
Dispose of waste according to local regulations.

Fire Precautions:
Isopropyl myristate is non-flammable; however, it may support combustion under certain conditions.
Keep away from open flames and high temperatures.


Storage:

Storage Temperature:
Store Isopropyl myristate in a cool, dry place.
Keep away from direct sunlight and heat sources.

Container Material:
Store in containers made of materials compatible with Isopropyl myristate, such as high-density polyethylene (HDPE) or glass.
Check for any signs of container deterioration or leaks.

Separation from Incompatible Substances:
Keep away from strong oxidizing agents.
Store separately from acids, bases, and reactive chemicals.

Handling Containers:
Handle containers carefully to prevent damage or leakage.
Use appropriate equipment for lifting and moving containers.

Grounding:
Ensure that containers are properly grounded to prevent static electricity buildup.

Labeling:
Clearly label containers with product information, hazard symbols, and safety precautions.
Follow local regulations for labeling requirements.

Shelf Life:
Check the shelf life of Isopropyl myristate as specified by the manufacturer.
Dispose of expired or degraded products properly.
ISOPROPYL OLEATE
cas no 112-11-8 Isopropyl 9Z-octadecenoate; 9-Octadecenoic acid (Z)-, 1-methylethyl ester; Oleic acid, isopropyl ester; 1-methylethyl ester; i-Propyl 9-octadecenoate; isopropyl oleate, AldrichCPR; 1-Methylethyl-9-octadecenoate;
ISOPROPYL PALMITATE
IPP; Isopal; Hexadecanoic acid, 1-methylethyl ester; Palmitic acid, Isopropyl ester; Deltyl; Hexadecanoic acid, Isopropyl ester; Isopal; Isopropyl hexadecanoate; 1-methylethyl hexandecanoate; cas no: 142-91-6
ISOPROPYL PALMITATE (IPP)
DESCRIPTION:
An ester derived from isopropyl alcohol and palmitic acid, Isopropyl Palmitate (IPP) is used in many industrial processes as an emollient, thickening agent, moisturizer and anti-static agent.
Acme-Hardesty manufactures a vegetable-based Isopropyl Palmitate (IPP) containing a minimum 90 percent C16 esters.
A high-quality product suitable for the most demanding applications, our isopropyl palmitate is the choice of some of today’s leading pharma, personal care and food and beverage manufacturers.


CAS#: 142-91-6
INCI NAME: Isopropyl Palmitate
CHEMICAL NAME: Hexadecanoic Acid, Isopropyl Ester


SYNONYMS OF ISOPROPYL PALMITATE (IPP):
Lexol® 3975,Lexol® IPP MB,Lexol® IPP-NF MB,PALMESTER 1517 Isopropyl Palmitate,PARYOL IPP,AE Ester IPP,Polymol® IPP,Dermol IPP,Wickenol 111,BASF Isopropyl Palmitate,BergaCare EM,16,BergaCare EM-16 /MB,MIRITOL™ IP,CremerCOOR® IPP,Isopropyl Palmitate 98%,Versagel® MP 1600,Versagel® MP 750,Hostacerin® SAF,MASSOCARE IPP,Crodamol™ IPP,DomusCare® IPP,ERCAREL IPP V,TEGOSOFT® P,QUERCEVITA®,HallStar® IPP,Jeechem IPP NF,Jeelux® DMIPP,Isopropyl Palmitate,IPP,Propal™ NF,MelinOil™,SWT-7™ L,Isopropyl Palmitate (IPP),MIPEARL IPP,Natura-tec Ultrafeel IPP,Nikkol IPP,Radia® 7732,Protachem™ IPP,Rita IPP NF,Ritalan C,Regrease IPP,COVALIP® 22,DUB IPP,Thorcoest IPP,Liponate® IPP,HelioPro IPP 50H



Isopropyl Palmitate (IPP) is fatty acid ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is used in personal care products to enhance their moisturising and skin conditioning properties.
Isopropyl Palmitate (IPP) by McKinley Resources acts as an emollient, moisturizer and thickening agent.

Isopropyl Palmitate (IPP) is a compound of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) contains fatty acid, composed of vitamin A and an antioxidant.
Isopropyl Palmitate (IPP) can easily penetrate the skin and offers softness and suppleness.
Isopropyl Palmitate (IPP) is used in moisturizers, lipstick, facial treatments, eye shadow, hair conditioner, styling gel, concealer, foundation, lip gloss and anti-aging products.
Isopropyl Palmitate (IPP) complies with TSCA and DSL.

Blossom offers premium quality Isopropyl Palmitate/IPP in bulk.
Isopropyl Palmitate (IPP) is in odorless and colorless liquid form for versatile application.
Isopropyl Palmitate (IPP) is produced using isopropyl alcohol and palmitic acid via esterification process.

C16 Ester is 90% minimum.
Isopropyl Palmitate (IPP) is in liquid form at ambient temperature.
Isopropyl Palmitate (IPP) may solidify at cold temperatures (warming up will bring it back to liquid form).

Isopropyl Palmitate (IPP) works as an emollient, thickening agent, lubricant, and texture enhancer in beauty products.
Isopropyl Palmitate (IPP) helps to enhance the penetration of ingredients.
Isopropyl Palmitate (IPP) has skin conditioning, moisturizing, anti-static and binding properties.

Isopropyl Palmitate (IPP) is a common carrier for fragrance oils/deodorants.
Isopropyl Palmitate (IPP) has very good spreading properties and gives a silky touch to the products.
Isopropyl Palmitate (IPP) is one of the favorite ingredient amongst formulators for its versatile application.

Isopropyl Palmitate is a commonly used raw material in the cosmetics industry, known for its versatile properties and various benefits.
Isopropyl Palmitate (IPP) is an ester derived from isopropyl alcohol and palmitic acid.

Isopropyl Palmitate is a widely used raw material in the cosmetics industry, known for its versatile properties and various benefits.
Here are some key benefits of Isopropyl Palmitate as a raw material in cosmetics:

Emollient Properties:
Isopropyl Palmitate acts as an effective emollient, helping to moisturize and soften the skin.
Isopropyl Palmitate (IPP) forms a protective barrier on the skin's surface, preventing moisture loss and enhancing the overall texture and appearance of cosmetic products.

Enhanced Spreadability:
Isopropyl Palmitate improves the spreadability of cosmetic formulations.
Isopropyl Palmitate (IPP) helps the product glide smoothly over the skin, facilitating even distribution and easy application.
This ensures that the product is evenly applied and absorbed, providing uniform coverage.

Smooth and Silky Texture:
This ingredient imparts a smooth and silky texture to cosmetic products.
Isopropyl Palmitate (IPP) gives a luxurious and velvety feel upon application, enhancing the sensory experience for the user.

Non-Greasy Finish:
Isopropyl Palmitate has a non-greasy texture, making it suitable for use in various cosmetic formulations.
Isopropyl Palmitate (IPP) absorbs quickly into the skin, leaving behind a non-oily and lightweight finish without any greasiness or stickiness.

Compatibility:
Isopropyl Palmitate is compatible with a wide range of cosmetic ingredients, making it versatile for use in different formulations.
Isopropyl Palmitate (IPP) blends well with other emollients, oils, and active ingredients, allowing formulators to achieve desired product characteristics and performance.

Solvent and Carrier:
Isopropyl Palmitate acts as a solvent, aiding in the dissolution and dispersion of certain active ingredients within a cosmetic formulation.
Isopropyl Palmitate (IPP) also serves as a carrier, helping deliver other ingredients into the skin effectively.

Stability:
Isopropyl Palmitate contributes to the stability and shelf life of cosmetic products.
Isopropyl Palmitate (IPP) helps prevent the separation of oil and water phases, ensuring the formulation remains well-mixed and consistent over time.

Versatile Application:
Isopropyl Palmitate finds applications in various cosmetic products, including lotions, creams, moisturizers, makeup products, and hair care products.
Its versatility makes it suitable for use in different types of products.

Isopropyl Palmitate, or IPP-NF, is a highly versatile ingredient that finds extensive use in various personal care products such as moisturizers, lotions, creams, and cosmetics.
It is known for its anti-tackiness properties and conforms to the requirements of the National Formulary monograph for Isopropyl Palmitate.

With its low viscosity and surface tension, IPP-NF is an excellent spreading ester, making it a popular choice in various personal care products.
It has a low to no odor, which means it will not affect the fragrance of your final product.
For best results, incorporate Isopropyl Palmitate at recommended levels to achieve desired skin-soothing and textural benefits.

For best results, use at a concentration of 1% to 5% in your formulations.
It's important to store IPP-NF in a cool and dry place, preferably in its original sealed container.

Avoid exposing it to temperatures above 32°C (90°F) for extended periods of time.
Also, make sure to keep it at a temperature above 15°C (59°F) to prevent freezing.
Proper storage will help ensure the quality and effectiveness of the product.


FUNCTIONS OF ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is one of the important additives for high-grade cosmetics.
Isopropyl Palmitate (IPP) can be used as emulsifier and moistening agent for cosmetics. Is derived from palm oil and is used as a thickening agent.
Isopropyl Palmitate (IPP) can also be used as a moisturizer and as an antistatic agent.




USES & APPLICATIONS OF ISOPROPYL PALMITATE (IPP):
Pharmaceuticals:
Topical Medicinal Preparations
Personal Care and Cosmetics:
Emollient, Moisturizer, Thickening Agent
Flavor and Fragrance:
Solvent, Binder, Diluent

Isopropyl palmitate is a colorless liquid with a faint odor.
When stored properly at room temperature, it has a shelf life of up to two years from the date of manufacture.
Our product is tested to ASTM standards to confirm a maximum acid value of 0.5 mg KOH/g, a maximum iodine value of 1g/100g and a moisture content of no more than 0.1 percent.
For a detailed list of specs, download the product data sheet.

Use isopropyl palmitate in the preparation of topical medications, personal care products and cosmetics.
Isopropyl Palmitate (IPP) can also be used a solvent, binder and diluent for food-grade flavors and fragrances.
To obtain more information about potential applications or for answers to any of your questions about our isopropyl palmitate, contact Acme-Hardesty.


Isopropyl Palmitate (IPP) is an economical liquid ester made from the reaction of vegetal Palmitic Acid and petrochemical Isopropyl Alcohol.
Isopropyl Palmitate (IPP) conforms to the requirements of the National Formulary monograph for Isopropyl Palmitate.

Isopropyl Palmitate (IPP) is a light non-occlusive emollient with a soft, dry, non-oily feel.
Isopropyl Palmitate (IPP) is used as pigment binder, diluent, and solubilizing agent for mineral oil, silicones, lanolin, and fragrances in many personal care product applications.


Emollient:
Isopropyl palmitate acts as an emollient, helping to soften and smooth the skin.
Isopropyl Palmitate (IPP) forms a thin, occlusive layer on the skin's surface, preventing moisture loss and improving the overall texture and hydration of the skin.

Texture Modifier:
Isopropyl palmitate is used to modify the texture and sensory feel of cosmetic products.
Isopropyl Palmitate (IPP) imparts a silky, smooth, and non-greasy sensation, enhancing the spreadability and absorption of the formulation.

Solvent:
Isopropyl palmitate functions as a solvent, aiding in the solubilization and dispersion of other ingredients in cosmetic formulations.
Isopropyl Palmitate (IPP) helps to improve the compatibility and stability of various substances, ensuring they are evenly distributed throughout the product.

Enhances Delivery:
Isopropyl palmitate can enhance the penetration and absorption of other active ingredients into the skin.
Isopropyl Palmitate (IPP) helps to facilitate the delivery of beneficial compounds, allowing them to reach deeper layers of the skin and exert their effects.

Hair Care:
Isopropyl palmitate is used in hair care products, including conditioners, styling products, and leave-in treatments.
Isopropyl Palmitate (IPP) helps to improve the manageability, softness, and shine of the hair.

Makeup Formulations:
Isopropyl palmitate is often found in makeup products such as foundations, lipsticks, and eyeshadows.
Isopropyl Palmitate (IPP) helps to create a smooth and even application, improves adherence to the skin, and enhances the color payoff.

Fragrance Ingredient:
Isopropyl palmitate can serve as a carrier for fragrances in perfumes, colognes, and other scented products.
Isopropyl Palmitate (IPP) helps to stabilize and release the fragrance over time, improving the longevity and diffusion of the scent.

Isopropyl Palmitate (IPP) is used for After Sun Skin Care
Isopropyl Palmitate (IPP) is used for Bath Additives
Isopropyl Palmitate (IPP) is used for Cleansing Wipes

Isopropyl Palmitate (IPP) is used for Eye Area Color Cosmetics
Isopropyl Palmitate (IPP) is used for Facial Cleansers
Isopropyl Palmitate (IPP) is used for Facial Color Cosmetics

Isopropyl Palmitate (IPP) is used for Facial Skin Care
Isopropyl Palmitate (IPP) is used for Foot Care
Isopropyl Palmitate (IPP) is used for Hair Conditioners

Isopropyl Palmitate (IPP) is used for Hand & Body Care
Isopropyl Palmitate (IPP) is used for Lip Care
Isopropyl Palmitate (IPP) is used for Nail Care

Isopropyl Palmitate (IPP) is used for Personal Lubricants
Isopropyl Palmitate (IPP) is used for Self-Tanners
Isopropyl Palmitate (IPP) is used for Shaving Products
Isopropyl Palmitate (IPP) is used for Styling Aids



CHEMICAL AND PHYSICAL PROPERTIES OF ISOPROPYL PALMITATE (IPP)

Acid Value (mg KOH/g), 0.5 Max
Saponification Value (mg KOH/g), 185-191
Color (APHA), 25 Max
Moisture Content (%), 0.1 Max
Ash Content (%), 0.1 Max
Peroxide Value (meq/Kg), 0.6 Max
Viscosity (mPa.s) 20℃, 5-10
Density (g/cm3) 20℃, 0.852-0.855
Refractive Index 20℃, 1.436-1.440
Composition (%),
C16, 95 Min
Appearance (25°C), Clear liquid
Odor, Practically none
Color (APHA = PtCo), 15
Acid Value (mg KOH/g), 0.2
Saponification Value (mg KOH/g), 188
Specific Gravity (25°C/25°C), 0.852
Density (g/cc), 0.85
Viscosity (cP, 25°C), 6.7
Viscosity (cps, 60°C), 2.5
Refractive Index (25°C), 1.436
Iodine Value (gI2/100g), 0.4
Actives, %, > 95
Boiling Point (°C), 172
Flash Point (°C), 166
Melting Point (°C), 13
Molecular Weight (daltons), ~298
RVOC, U.S. EPA (%), 0
Dielectric Constant (25°C), 3.18
Insoluble In, Water
Soluble In, Isopropyl AlcoholLanolinMineral OilSiliconesVegetable Oil
Solvency Of, Avobenzone (15%)Bemotrizinol (4.5%)Ethylhexyl Triazone (3%)Oxybenzone (20+%)
Toxicology Profile, CIR Expert Panel: Safe at up to >50% in present practices of useJACT/IJT Reference(s): J. Amer. Coll. Toxicol. JACT 1(2):13-35, 1982LD50: > 5ml/kgOcular / Eye Irritation: MinimalSkin Irritation: Slight
Packaging, Drum - 390, 385.8lbs
Origin: Synthetic
Shelf life: 2 years from mfg. date
Freight Classification: NMFC 43940 S 2 CL 85
Kosher Status: Not Kosher
Flash Point: >230 øF
Melting Point: 11-13 øC
API: NO
Allergen: NO
Hazmat: YES
Molecular Weight: 298.50 g/mol
Appearance, Colorless transparent
Acid Value (mgKOH/g), 0.5 Max
Assay, 98% Min
Freezing Point, 16C Max
Refractive Index (20C), 1.435-1.440
Odor, No peculiar odor
Parameter, Value
CAS Number, 142-91-6
Chemical formula, C19H38O2
Molar mass, 298.51 g•mol−1
Density, 0.8525 g/cm3
Melting point, 13.5 °C (56.3 °F; 286.6 K)
Solubility in water, Insoluble


SAFETY INFORMATION ABOUT ISOPROPYL PALMITATE (IPP):
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product


ISOPROPYL PALMITATE (IPP)
Isopropyl Palmitate (IPP) is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol.
Isopropyl Palmitate (IPP) is in liquid form at ambient temperature.
Isopropyl Palmitate (IPP) is made from vegetable-based C16 Palmitic Acid and Isopropyl Alcohol.


CAS Number: 142-91-6
EC Number: 205-571-1
MDL number: MFCD00008993
CHEMICAL NAME: Hexadecanoic Acid, Isopropyl Ester
Linear Formula: CH3(CH2)14COOCH(CH3)2
Molecular Formula: C19H38O2


Isopropyl Palmitate (IPP) is a clear colorless liquid.
Isopropyl Palmitate (IPP) is a clear, colorless to pale yellow-colored, practically odorless viscous liquid that solidifies at less than 16°C.
Isopropyl Palmitate (IPP) is an analog of isopropyl myristate and an aliphatic ester used as a flavoring ingredient in food industry.


Isopropyl Palmitate (IPP) is one of the volatile compounds found in Psidium salutare fruits and boiled buckwheat flour.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.


Isopropyl Palmitate (IPP) is a colorless clear oily liquid.
Isopropyl Palmitate (IPP) is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol.
Isopropyl Palmitate (IPP) has a role as a human metabolite.


Isopropyl Palmitate (IPP) is a fatty acid ester and an isopropyl ester.
Isopropyl Palmitate (IPP) is functionally related to a hexadecanoic acid.
Isopropyl Palmitate (IPP) is a natural product found in Mangifera indica, Apium graveolens, and other organisms with data available.


Isopropyl Palmitate (IPP) is produced using isopropyl alcohol and palmitic acid via esterification process.
Isopropyl Palmitate (IPP) is in liquid form at ambient temperature.
Isopropyl Palmitate (IPP) may solidify at cold temperatures (warming up will bring it back to liquid form).


Isopropyl Palmitate (IPP) is an ester derived from isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is a versatile ingredient commonly used in the cosmetics and personal care industry.
Isopropyl Palmitate (IPP) is produced adhering to the strictest standards, ensuring superior purity, consistency, and performance.


Isopropyl Palmitate (IPP) is a clear, colorless light liquid, it is an emollient and lubricating agent, commonly used in making cosmetic products, it is a light penetrating oil which doesn't leave skin greasy feel.
Isopropyl Palmitate (IPP) is a commonly used raw material in the cosmetics industry, known for its versatile properties and various benefits.


Isopropyl Palmitate (IPP) is an ester derived from isopropyl alcohol and palmitic acid.
Overall, Isopropyl Palmitate (IPP) offers emollient properties, enhanced spreadability, smooth texture, compatibility, stability, and versatility, making it a valuable raw material in the cosmetics industry.


Isopropyl Palmitate (IPP) is made from vegetable-based C16 Palmitic Acid and Isopropyl Alcohol.
Isopropyl Palmitate (IPP) is a fatty acid ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is produced by the transesterification of the methyl ester with isopropyl alcohol.


The process includes the removal of methanol by distillation or esterification of the fatty acid with isopropyl alcohol.
Multi-functional fatty acid made of the ester of isopropyl alcohol and palmitic acid derived from renewable vegetable oils.
Isopropyl Palmitate (IPP) acts is an emollient, moisturizer, wetting agent, and anti-static agent.


Isopropyl Palmitate (IPP) is readily biodegradable and is GMO-free.
Saponification value of Isopropyl Palmitate (IPP) is 183-193.
Isopropyl Palmitate (IPP) is a fatty acid ester of isopropyl alcohol and palmitic acid.


Isopropyl Palmitate (IPP) is the ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is an emollient, moisturizer, thickening agent, and anti-static agent .
The chemical formula of Isopropyl Palmitate (IPP) is CH3(CH2)14COOCH(CH3)2.


Isopropyl Palmitate (IPP) is related to isopropyl myristate (IPM), the difference being IPP is derived from palmitic fatty acid (C16) and IPM is derived from myristic fatty acid (C14).
Since we’re a little more familiar with IPM, we’ll end up contrasting and comparing the two at some point, so…


Isopropyl Palmitate (IPP) is an ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is a non-branched saturated fatty acid ester obtained from isopropanol and palmitic acid, from palm oil.
Isopropyl Palmitate (IPP) is a clear liquid with a melting point of 13 ºC.


Isopropyl Palmitate (IPP) is produced from palmitic acid, derived from vegetable oil & isopropanol (or isopropyl alcohol).
Isopropyl Palmitate (IPP) is the ester of palmitic acid and isopropanol.
Isopropyl Palmitate (IPP) is a colorless and oily liquid.


Isopropyl Palmitate (IPP) is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol.
Isopropyl Palmitate (IPP) has a role as a human metabolite.
Isopropyl Palmitate (IPP) is a fatty acid ester and an isopropyl ester.


Isopropyl Palmitate (IPP) derives from a hexadecanoic acid.
Isopropyl Palmitate (IPP) is fatty acid ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) is used in moisturizers, lipstick, facial treatments, eye shadow, hair conditioner, styling gel, concealer, foundation, lip gloss and anti-aging products.


Isopropyl Palmitate (IPP) complies with TSCA and DSL.
Isopropyl Palmitate (IPP), a clear colorless liquid, is chemically an ester of isopropanol and palmitic acid.
Isopropyl Palmitate (IPP) also has an influence on the viscosity of the formulation and prevents greasy glossiness on the skin.


Isopropyl Palmitate (IPP) is Hexadecanoic acid, 1-methylethyl ester.
Isopropyl Palmitate (IPP) is a fatty acid ester of propan-2-ol and palmitic acid.
Isopropyl Palmitate (IPP) is supplied as a clear oily liquid that may be colourless or slightly yellow, but practically odourless.



USES and APPLICATIONS of ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is used pharmaceutic aid (vehicle, oleaginous).
Isopropyl Palmitate (IPP) is an emollient and moisturizer, it also acts as a binder and solvent.
Similar to isopropyl myristate, it is produced from the combination of palmitic acid (coconut or palm oil) and isopropyl alcohol. enzymes are able to metabolize Isopropyl Palmitate (IPP) and studies do not show allergic reactions or toxicity.


Isopropyl Palmitate (IPP) is used to formulate and evaluate the suitability of pluronic lecithin organogels containing flurbiprofen for topical application and to characterize microemulsion systems of Isopropyl Palmitate (IPP).
Isopropyl Palmitate (IPP) is a fatty acid ester obtained by the formal condensation of carboxy group of palmitic acid with propan-2-ol.


Isopropyl Palmitate (IPP) works as an emollient, thickening agent, lubricant, and texture enhancer in beauty products.
Isopropyl Palmitate (IPP) helps to enhance the penetration of ingredients.
Isopropyl Palmitate (IPP) has skin conditioning, moisturizing, anti-static and binding properties.


Isopropyl Palmitate (IPP) is a common carrier for fragrance oils/deodorants.
Isopropyl Palmitate (IPP) has very good spreading properties and gives a silky touch to the products.
Isopropyl Palmitate (IPP) is one of the favorite ingredient amongst formulators for its versatile application.


Isopropyl Palmitate (IPP) is used Skin Care, Hair Care, Baby Care, Nail Care, Lip Care, Cosmetics, Massage, and Aromatherapy.
Isopropyl Palmitate (IPP) is used emollient & emulsifier in cosmetic creams, cosmetic oils, in hair tonics, hair dressings, hair pomades, sun tan & other lotions, other cosmetics, topical medicinal preparations.


Isopropyl Palmitate (IPP) is used Cosmetics, Personal care, Moisturisers, Sun care, Body care, Face care, and Hair care.
Isopropyl Palmitate (IPP) is used in these perfume types but not limited to them.
Unleash the full potential of your products with our high-grade Isopropyl Palmitate (IPP).


This versatile ingredient, Isopropyl Palmitate (IPP), is widely used across multiple industries due to its superb qualities and wide range of applications.
Within the realm of cosmetics and personal care, Isopropyl Palmitate (IPP) is a favored emollient that moisturizes and softens the skin, offering a silky, non-greasy feel to lotions, creams, and other skincare products.


Isopropyl Palmitate (IPP)'s ability to help other ingredients penetrate the skin makes it a staple in many cosmetic formulations.
Additionally, Isopropyl Palmitate (IPP) serves as a fragrance ingredient, enhancing the scent profile of perfumes, body sprays, and other scented products.
In the food and beverage industry, Isopropyl Palmitate (IPP) functions as an effective food additive and flavor ingredient, improving the texture and taste of a broad spectrum of food and drink items, thereby enriching the consumer’s culinary experience.


The pharmaceutical industry also harnesses the benefits of Isopropyl Palmitate (IPP).
As an excipient, Isopropyl Palmitate (IPP) aids in the delivery of active pharmaceutical ingredients, optimizing the effectiveness of medications and ensuring maximum therapeutic benefits.


Isopropyl Palmitate (IPP) serves as a chemical intermediate in the chemical industry, facilitating the creation of a variety of essential products.
Isopropyl Palmitate (IPP)'s role as a plasticizer in the plastics and polymer industry enhances the flexibility and workability of plastic products, contributing to their longevity and performance.


Isopropyl Palmitate (IPP) is a commonly used raw material in the cosmetics industry, known for its versatile properties and various benefits.
Isopropyl Palmitate (IPP) is a widely used raw material in the cosmetics industry, known for its versatile properties and various benefits.
This specialty cosmetic ingredient, Isopropyl Palmitate (IPP), have excellent emollient and spreading properties, and exceptional oxidative stability which make it perfect for cosmetic applications.


Isopropyl Palmitate (IPP) makes the skin smooth and soothing without leaving a greasy and oil feeling on the skin.
Isopropyl Palmitate (IPP) is used in many personal care and cosmetic products such as facial creams, lotions, tanning gels, deodorants, perfumes, make-up, aftershave, lip balm, pharmaceutical creams, etc.


Isopropyl Palmitate (IPP) is suitable for the most demanding applications, like pharma, personal care, and food and beverages.
Isopropyl Palmitate (IPP) is used Bath oils, skin creams, sunscreens, shaving creams, vanishing creams, hair conditioner, pre-shaves & aftershaves, shampoos, bath oils, aerosol antiperspirants and deodorants.


Isopropyl Palmitate (IPP) is an emollient, moisturizer, thickening agent, and anti-static agent.
Isopropyl Palmitate (IPP) is a traditional, fast spreading emollient for modern cosmetic applications.
Isopropyl Palmitate (IPP) is a clear, colorless and nearly odorless oil of intermediate polarity, with a low molecular weight, and a spreading value of approx. 1000 mm²/10 min.


Isopropyl Palmitate (IPP) has a cloud point of < 15°C, a viscosity (20°C) of 7-8 mPas, and a saponification value of 185-190.
Isopropyl Palmitate (IPP) is the ester of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) has the functions of moistening, penetrating when used in cosmetics.


The use level in cosmetics of Isopropyl Palmitate (IPP) is 2-10%.
Isopropyl Palmitate (IPP) can be used in sol, hair conditioner, bath oil, skin cream, sunblocking cream and shaving cream.
Isopropyl Palmitate (IPP) is suitable for the most demanding applications, like pharma, personal care, and food and beverages.


Isopropyl Palmitate (IPP) acts as topical medicinal preparations in pharmaceuticals; emollient, moisturizer, thickening agent in personal care and cosmetics; solvent, binder, diluent in flavor and fragrance.
Isopropyl Palmitate (IPP) is also used in hair care to improve luster, quality, and silkiness.


Isopropyl Palmitate (IPP) is widely used in cosmetics.
As a moisturizer for skin care, Isopropyl Palmitate (IPP) can be effectively absorbed by the skin.
As awetting agent and penetrant, Isopropyl Palmitate (IPP) can be used in sol products, bath oil, skin cream, sunscreen, shaving cream, and hair conditioner, among others.


Isopropyl Palmitate (IPP) is used as emollient and emulsifier (cosmetics and topical medicines) and as plasticizer.
Isopropyl Palmitate (IPP) is used for chemical synthesis, metal extraction or refining and processing of metals, textile processing, and in lubricants and additives.


Cosmetic formulations of Isopropyl Palmitate (IPP): binding, fragrance, perfuming, emollient.
Industrial uses of Isopropyl Palmitate (IPP): manufacturer of washing and cleaning products, polymers, textile treatment products and dyes, lubricants and greases, adhesives, sealants, polishes and waxes.


Isopropyl Palmitate (IPP) is a fast-spreading emollient suitable for all cosmetic applications.
Isopropyl Palmitate (IPP) is used as a cosmetics deep agent and skin moisturizer, penetrant.
Isopropyl Palmitate (IPP) has excellent penetration, moisturizing and softening effect on the skin, and is used for emulsifiers and moisturizers for cosmetics.


Isopropyl Palmitate (IPP) can be used in cosmetics such as sol product, hair conditioner, skin cream, sunscreen and shaving cream.
Isopropyl Palmitate (IPP) is widely used in cosmetics and pharmaceuticals (where it is emulsified with water to improve absorption of the product into the skin).


Isopropyl Palmitate (IPP) is used raw material for spin finishes and oiling agent for textile, Rubber processing agent, Plastic lubricant, Paint additive, Ink additive.
Isopropyl Palmitate (IPP) is used additives for pharmaceuticals and Friction modifier.


Isopropyl Palmitate (IPP) is a solvent fixative skin-perfumes.
Isopropyl Palmitate (IPP) acts as a physical fixative for perfumes.
Isopropyl Palmitate (IPP) acts as an emollient, moisturizer and thickening agent.


Isopropyl Palmitate (IPP) is a compound of isopropyl alcohol and palmitic acid.
Isopropyl Palmitate (IPP) contains fatty acid, composed of vitamin A and an antioxidant.
Isopropyl Palmitate (IPP) can easily penetrate the skin and offers softness and suppleness.


Isopropyl Palmitate (IPP) is used in personal care products to enhance their moisturising and skin conditioning properties.
An ester derived from isopropyl alcohol and palmitic acid, Isopropyl Palmitate (IPP) is used in many industrial processes as an emollient, thickening agent, moisturizer and anti-static agent.


Acme-Hardesty manufactures a vegetable-based Isopropyl Palmitate (IPP) containing a minimum 90 percent C16 esters.
A high-quality product suitable for the most demanding applications, Isopropyl Palmitate (IPP) is the choice of some of today’s leading pharma, personal care and food and beverage manufacturers.


Isopropyl Palmitate (IPP) is used in Pharmaceuticals, Topical Medicinal Preparations, Personal Care and Cosmetics, Emollient, Moisturizer, Thickening Agent, Flavor and Fragrance, Solvent, Binder, Diluent.


-Solvent uses of Isopropyl Palmitate (IPP):
Isopropyl Palmitate (IPP) functions as a solvent, aiding in the solubilization and dispersion of other ingredients in cosmetic formulations.
Isopropyl Palmitate (IPP) helps to improve the compatibility and stability of various substances, ensuring they are evenly distributed throughout the product.


-Enhances Delivery uses of Isopropyl Palmitate (IPP):
Isopropyl palmitate can enhance the penetration and absorption of other active ingredients into the skin.
Isopropyl Palmitate (IPP) helps to facilitate the delivery of beneficial compounds, allowing them to reach deeper layers of the skin and exert their effects.


-Hair Care uses of Isopropyl Palmitate (IPP):
Isopropyl palmitate is used in hair care products, including conditioners, styling products, and leave-in treatments.
Isopropyl Palmitate (IPP) helps to improve the manageability, softness, and shine of the hair.


-Makeup Formulations uses of Isopropyl Palmitate (IPP):
Isopropyl palmitate is often found in makeup products such as foundations, lipsticks, and eyeshadows.
Isopropyl Palmitate (IPP) helps to create a smooth and even application, improves adherence to the skin, and enhances the color payoff.


-Fragrance Ingredient uses of Isopropyl Palmitate (IPP):
Isopropyl palmitate can serve as a carrier for fragrances in perfumes, colognes, and other scented products.
Isopropyl Palmitate (IPP) helps to stabilize and release the fragrance over time, improving the longevity and diffusion of the scent.


-Emollient uses of Isopropyl Palmitate (IPP):
Isopropyl Palmitate (IPP) acts as an emollient, helping to soften and smooth the skin.
Isopropyl Palmitate (IPP) forms a thin, occlusive layer on the skin's surface, preventing moisture loss and improving the overall texture and hydration of the skin.


-Texture Modifier uses of Isopropyl Palmitate (IPP):
Isopropyl Palmitate (IPP) is used to modify the texture and sensory feel of cosmetic products.
Isopropyl Palmitate (IPP) imparts a silky, smooth, and non-greasy sensation, enhancing the spreadability and absorption of the formulation.


-Applications in Pharmaceutical Formulation or Technology uses of Isopropyl Palmitate (IPP):
Isopropyl Palmitate (IPP) is a nongreasy emollient with good spreading characteristics, used in topical pharmaceutical formulations and cosmetics such as: bath oils; creams; lotions; make-up; hair care products; deodorants; lip products; suntan preparations; and pressed powders.
Isopropyl Palmitate (IPP) is an established penetration enhancer for transdermal systems.
Isopropyl Palmitate (IPP) has also been used in controlled-release percutaneous films.



PHARMACEUTICAL APPLICATIONS OF ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is a nongreasy emollient with good spreading characteristics, used in topical pharmaceutical formulations and cosmetics such as: bath oils; creams; lotions; make-up; hair care products; deodorants; lip products; suntan preparations; and pressed powders.
Isopropyl Palmitate (IPP) is an established penetration enhancer for transdermal systems.
Isopropyl Palmitate (IPP) has also been used in controlled-release percutaneous films.



APPLICATIONS AND CHARACTERISTICS OF ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is a colorless liquid with a faint odor. When stored properly at room temperature, it has a shelf life of up to two years from the date of manufacture.
Isopropyl Palmitate (IPP) is used in the preparation of topical medications, personal care products and cosmetics.

Isopropyl Palmitate (IPP) can also be used a solvent, binder and diluent for food-grade flavors and fragrances.
Isopropyl Palmitate (IPP) has rapid spreading properties and can be used as an emulsifier, solvent, humectant and penetration enhancer in creams, lotions, sprays, and gels.



PROPERTIES OF ISOPROPYL PALMITATE (IPP):
Cosmetic and pharmaceutical uses of Isopropyl Palmitate (IPP): Oil base with low viscosity, good adaptation to skin.
Isopropyl Palmitate (IPP) is colorless no odor.
Isopropyl Palmitate (IPP) is suitable for cream-milk lotion, emollient and shampoo.



KEY BENEFITS OF ISOPROPYL PALMITATE (IPP) AS A RAW MATERIAL IN COSMETICS:
*Emollient Properties:
Isopropyl Palmitate (IPP) acts as an effective emollient, helping to moisturize and soften the skin.
Isopropyl Palmitate (IPP) forms a protective barrier on the skin's surface, preventing moisture loss and enhancing the overall texture and appearance of cosmetic products.


*Enhanced Spreadability:
Isopropyl Palmitate (IPP) improves the spreadability of cosmetic formulations.
Isopropyl Palmitate (IPP) helps the product glide smoothly over the skin, facilitating even distribution and easy application.
This ensures that Isopropyl Palmitate (IPP) is evenly applied and absorbed, providing uniform coverage.


*Smooth and Silky Texture:
Isopropyl Palmitate (IPP) imparts a smooth and silky texture to cosmetic products.
Isopropyl Palmitate (IPP) gives a luxurious and velvety feel upon application, enhancing the sensory experience for the user.

*Non-Greasy Finish:
Isopropyl Palmitate (IPP) has a non-greasy texture, making it suitable for use in various cosmetic formulations.
Isopropyl Palmitate (IPP) absorbs quickly into the skin, leaving behind a non-oily and lightweight finish without any greasiness or stickiness.


*Compatibility:
Isopropyl Palmitate (IPP) is compatible with a wide range of cosmetic ingredients, making it versatile for use in different formulations.
Isopropyl Palmitate (IPP) blends well with other emollients, oils, and active ingredients, allowing formulators to achieve desired product characteristics and performance.


*Solvent and Carrier:
Isopropyl Palmitate (IPP) acts as a solvent, aiding in the dissolution and dispersion of certain active ingredients within a cosmetic formulation.
Isopropyl Palmitate (IPP) also serves as a carrier, helping deliver other ingredients into the skin effectively.


*Stability:
Isopropyl Palmitate (IPP) contributes to the stability and shelf life of cosmetic products.
Isopropyl Palmitate (IPP) helps prevent the separation of oil and water phases, ensuring the formulation remains well-mixed and consistent over time.


*Versatile Application:
Isopropyl Palmitate (IPP) finds applications in various cosmetic products, including lotions, creams, moisturizers, makeup products, and hair care products.
Its versatility makes Isopropyl Palmitate (IPP) suitable for use in different types of products.



PRODUCTION METHODS OF ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is prepared by the reaction of palmitic acid with propan-2-ol in the presence of an acid catalyst.
A high-purity material is also commercially available, which Isopropyl Palmitate (IPP) is produced by enzymatic esterification at low temperatures.



FUNCTION OF ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is one of the important additives for high-grade cosmetics.
Isopropyl Palmitate (IPP) can be used as emulsifier and moistening agent for cosmetics.
Isopropyl Palmitate (IPP) is derived from palm oil and is used as a thickening agent.
Isopropyl Palmitate (IPP) can also be used as a moisturizer and as an antistatic agent.



KEY PROPERTIES OF ISOPROPYL PALMITATE (IPP):
*Emollient with good spreading properties
*Halal
*Kosher
*Non-GMO
*RSPO MB available



BENEFIT OF ISOPROPYL PALMITATE (IPP):
*Highly Moisturizing
*Emollient
*Fast Absorption
*Good Cleaning Properties



METHOD OF MANUFACTURE OF ISOPROPYL PALMITATE (IPP):
Isopropyl Palmitate (IPP) is prepared by the reaction of palmitic acid with propan-2-ol in the presence of an acid catalyst.
A high-purity material is also commercially available, which is produced by enzymatic esterification at low temperatures.



PHYSICAL and CHEMICAL PROPERTIES of ISOPROPYL PALMITATE (IPP):
Physical state: liquid
Color: colorless
Odor: No data available
Melting point/freezing point:
Melting point/freezing point: 13,5 °C
Initial boiling point and boiling range: 160 °C at 3 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: 113 °C - closed cup
Autoignition temperature: 235 °C
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility No data available
Partition coefficient: n-octanol/water: No data available
Vapor pressure: 0,0000745 hPa at 25 °C
Density: 0,853 g/cm3
Relative density: No data available
Relative vapor density: No data available

Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: No data available
Other safety information: No data available
IUPAC Name: propan-2-yl hexadecanoate
INCHI: InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3
InChi Key: XUGNVMKQXJXZCD-UHFFFAOYSA-N
Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OC(C)C
Molecular Formula: C19H38O2
PubChem CID: 8907
Beilstein: 1786567
Molecular Weight: 298.5
Solubility: Not miscible or difficult to mix with water.
Boil Point(°C): 160°/2mmHg
Melt Point(°C): 13°C
Refractive Index: 1.438
Flash Point(°F): 235.4 °F
Flash Point(°C): 183°C
Boiling point: 1608C at 266 Pa (2 mmHg)
Freezing point: 13–158C
Refractive index: 1.436 at 258C for Propal.
Solubility: Soluble in acetone, chloroform, ethanol (95%), ethyl
acetate, mineral oil, propan-2-ol, silicone oils, vegetable oils, and
aliphatic and aromatic hydrocarbons; practically insoluble in
glycerin, glycols, and water.

Specific gravity: 0.852 at 258C for Propal.
Surface tension: 29 mN/m for Tegosoft P at 258C
Viscosity (dynamic): 5–10 mPa s (5–10 cP) at 258C
Molecular Weight: 298.5 g/mol
XLogP3-AA: 8.2
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 16
Exact Mass: 298.287180451 g/mol
Monoisotopic Mass: 298.287180451 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 21
Formal Charge: 0
Complexity: 224
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
IUPAC Name: propan-2-yl hexadecanoate
INCHI: InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3

InChi Key: XUGNVMKQXJXZCD-UHFFFAOYSA-N
Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OC(C)C
Molecular Formula: C19H38O2
PubChem CID: 8907
Beilstein: 1786567
Molecular Weight: 298.5
Solubility: Not miscible or difficult to mix with water.
Boil Point(°C): 160°/2mmHg
Melt Point(°C): 13°C
Refractive Index: 1.438
Flash Point(°F): 235.4 °F
Flash Point(°C): 183°C
IUPAC Name: Propan-2-yl hexadecanoate
Molecular Weight: 298.5
Molecular Formula: C19H38O2
Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OC(C)C
InChI: XUGNVMKQXJXZCD-UHFFFAOYSA-N
InChI Key: InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3
Boiling Point: 160 ℃ at 2mmHg
Melting Point: 13 °C
Flash Point: 183 °C
Density: 0.852g/ml
Solubility: Water insoluble, soluble in alcohol, acetone

Appearance: Colorless, slightly viscous liquid
Storage: Store in a closed container at a dry place at room temperature
Alpha Sort: Isopropyl palmitate
Complexity: 224
Composition: Isopropyl palmitate
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Exact Mass: 298.287180451
Heavy Atom Count: 21
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 0
Monoisotopic Mass: 298.287180451
Physical State: Liquid
Refractive Index: 1.438
Rotatable Bond Count: 16
Stability: Stable.
Topological Polar Surface Area: 26.3 Ų
IUPAC Name: propan-2-yl hexadecanoate
INCHI: InChI=1S/C19H38O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(20)21-18(2)3/h18H,4-17H2,1-3H3
InChi Key: XUGNVMKQXJXZCD-UHFFFAOYSA-N
Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OC(C)C
Molecular Formula: C19H38O2
PubChem CID: 8907

Beilstein: 1786567
Molecular Weight: 298.5
Chemical formula: C19H38O2
Molar mass: 298.511 g·mol−1
Density: 0.8525 g/cm3
Melting point: 13.5 °C (56.3 °F; 286.6 K)
Solubility in water: Insoluble
CAS Number:142-91-6
Chemical formula: C19H38O2
Molar mass: 298.51 g·mol−1
Density: 0.8525 g/cm3
Melting point: 13.5 °C (56.3 °F; 286.6 K)
Solubility in water: Insoluble
Melting point: 11-13 °C (lit.)
Boiling point: 160°C 2mm
Density: 0.852 g/mL at 25 °C (lit.)
vapor pressure: 0.007Pa at 25℃
refractive index: n20/D 1.438(lit.)
Flash point: >230 °F
storage temp.: 2-8°C
solubility: <0.001g/l
form: neat
color: Colourless

Odor: very sl. odor
Water Solubility: Not miscible or difficult to mix with water.
BRN: 1786567
InChIKey: XUGNVMKQXJXZCD-UHFFFAOYSA-N
LogP: 8.16
CAS DataBase Reference: 142-91-6(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS): ISOPROPYL PALMITATE
FDA 21 CFR: 310.545
EWG's Food Scores: 1
FDA UNII: 8CRQ2TH63M
NIST Chemistry Reference: Isopropyl palmitate(142-91-6)
EPA Substance Registry System: Isopropyl palmitate (142-91-6)
Cosmetics Info: Isopropyl Palmitate
Molecular Weight: 298.5
Exact Mass: 298.50
BRN: 1786567

EC Number: 205-571-1
UNII:8CRQ2TH63M
NSC Number: 69169
DSSTox ID: DTXSID9027104
Color/Form: Colorless liquid
HScode: 2915709000
PSA: 26.3
XLogP3: 8.2
Appearance: DryPowder
Density: 0.8404 g/cm3 @ Temp: 38 °C
Melting Point: 13.5 °C
Boiling Point: 160 °C @ Press: 2 Torr
Flash Point: >230 °F
Refractive Index: 1.443
Water Solubility: Not miscible or difficult to mix with water.
Storage Conditions: 2-8°C
Vapor Pressure: 5.59X10-5 mm Hg at 25 deg C (extrapolated)
Odor: Almost odorless
Henrys Law Constant: Henry's Law constant = 4.66X10-2 atm-cu m/mol at 25 °C (est)
Experimental Properties: Hydroxyl radical reaction rate constant = 2.21X10-11 cu cm/molec-sec at 25 °C (est)



FIRST AID MEASURES of ISOPROPYL PALMITATE (IPP):
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOPROPYL PALMITATE (IPP):
-Environmental precautions:
No special environmental precautions required.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of ISOPROPYL PALMITATE (IPP):
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOPROPYL PALMITATE (IPP):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection
*Skin protection:
Handle with gloves.
Wash and dry hands.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 480 min
*Body Protection:
Impervious clothing.
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
No special environmental precautions required



HANDLING and STORAGE of ISOPROPYL PALMITATE (IPP):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.



STABILITY and REACTIVITY of ISOPROPYL PALMITATE (IPP):
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available



SYNONYMS:
Emerest 2316
hexadecanoic acid isopropyl ester
hexadecanoic acid 1-methylethyl ester
isopropyl hexadecanoate
isopropylis palmitas
Isopropylpalmitat
Kessco IPP
Lexol IPP-NF
Liponate
IPP
palmitic acid isopropyl ester
Propal
Protachem IPP
Rita IPP
Stepan IPP
Super Refined Crodamol IPP
Tegosoft P
Unimate
IPP
Waglinol 6016
Wickenol 111
Isopropyl Palmitate (IPP)
Upmate IPP
Unipro IPP-20
1-Methylethyl ester1-methylethyl hexandecanoate
Crodamol IPP
1-methylethyl hexadecanoate
ISOPROPYL PALMITATE
142-91-6
Isopropyl hexadecanoate
Hexadecanoic acid, 1-methylethyl ester
Isopalm
Wickenol 111
Deltyl
Isopal
Propal
Deltyl prime
Emerest 2316
Tegester isopalm
Ja-fa ippkessco
Sinnoester PIT
Crodamol IPP
Plymouth IPP
Starfol IPP
Unimate IPP
Kessco IPP
Emcol-IP
Isopropyl n-hexadecanoate
Nikkol IPP
Stepan D-70
Palmitic acid, isopropyl ester
Estol 103
Usaf ke-5
JA-FA Ipp
1-Methylethyl hexadecanoate
Kessco isopropyl palmitate
Hexadecanoic acid, isopropyl ester
Hariol ipp
propan-2-yl hexadecanoate
Palmitic Acid Isopropyl Ester
NSC 69169
Estol 1517
HSDB 2647
Tegosoft P
Liponate IPP
UNII-8CRQ2TH63M
EINECS 205-571-1
Lexol IPP
8CRQ2TH63M
NSC-69169
BRN 1786567
CHEBI:84262
2-propyl hexadecanoate
AI3-05733
Isopropyl palmitate (NF)
Isopropyl palmitate [NF]
DTXSID9027104
EC 205-571-1
4-02-00-01167 (Beilstein Handbook Reference)
Isopropyl ester of hexadecanoic acid
NCGC00164128-01
WE(2:0(1Me)/16:0)
DTXCID507104
ISOPROPYL PALMITATE (II)
ISOPROPYL PALMITATE [II]
ISOPROPYL PALMITATE (MART.)
ISOPROPYL PALMITATE [MART.]
ISOPROPYL PALMITATE (USP-RS)
ISOPROPYL PALMITATE [USP-RS]
ISOPROPYL PALMITATE (EP IMPURITY)
ISOPROPYL PALMITATE [EP IMPURITY]
CAS-142-91-6
ISOPROPYL PALMITATE (EP MONOGRAPH)
ISOPROPYL PALMITATE [EP MONOGRAPH]
MFCD00008993
iso-propylpalmitate
isopropyl-palmitate
Hexadecanoic acid 1-methylethyl ester
Radia 7200
1-methylethyl hexandecanoate
SCHEMBL7743
Palmitic acid-isopropyl ester
Isopropyl palmitate, >=90%
CHEMBL139055
Hexadecanoic acid isopropyl ester
Hexadecanoic acid, 1-methyl ester
ISOPROPYL PALMITATE [HSDB]
ISOPROPYL PALMITATE [INCI]
WLN: 15VOY1 & 1
ISOPROPYL PALMITATE [VANDF]
NSC69169
Tox21_112085
Tox21_202558
ISOPROPYL PALMITATE [WHO-DD]
LMFA07010675
AKOS015902011
Tox21_112085_1
CS-W012142
HY-W011426
NCGC00164128-02
NCGC00260107-01
BS-15396
Hexadecanoic acidisopropyl n-hexadecanoate
Isopropyl palmitate, technical grade, 90%
FT-0631830
P0005
1-Methylethyl ester1-methylethyl hexandecanoate
D04632
A885074
SR-01000944752
J-007718
Q2631777
SR-01000944752-1
Isopropyl hexadecanoate, European Pharmacopoeia (EP) Reference Standard
Isopropyl palmitate, United States Pharmacopeia (USP) Reference Standard
Isopropyl palmitate, Pharmaceutical Secondary Standard; Certified Reference Material
Hexadecanoic acid, 1-methylethyl ester
Palmitic acid, isopropyl ester
Crodamol IPP
Deltyl
Deltyl Prime
Emcol-IP
Emerest 2316
Hexadecanoic acid, isopropyl ester
Isopal
Isopalm
Kessco IPP
Propal
Sinnoester PIT
Stepan D-70
Wickenol 111
Estol 103
Isopropyl n-hexadecanoate
Ja-fa ippkessco
Plymouth IPP
Starfol IPP
Tegester isopalm
Unimate IPP
USAF KE-5
Isopropyl hexadecanoate
Ja-fa ipp
Kessco isopropyl palmitate
Isopropyl ester of hexadecanoic acid
1-methylethyl hexandecanoate
Lexol IPP
Liponate IPP
Radia 7200
Tegosoft P
1-methylethyl hexadecanoate
2-propyl hexadecanoate
NSC 69169
Nikkol IPP
1-Methylethyl hexadecanoate
Crodamol IPP
Deltyl
Deltyl Prime
Emcol-IP
Emerest 2316
Estol 103
Hexadecanoic acid, 1-methylethyl ester
Hexadecanoic acid, isopropyl ester
Isopal
Isopalm
Isopropyl hexadecanoate
Isopropyl n-hexadecanoate
JA-FA IPP
JA-FA IPPKessco
Kessco IPP
Kessco isopropyl palmitate
Nikkol IPP
Palmitic acid, isopropyl ester
Plymouth IPP
Propal
Sinnoester PIT
Starfol IPP
Stepan D-70
Tegester isopalm
Unimate IPP
Wickenol 111
Propan-2-yl hexadecanoate
Isopropyl hexadecanoatel
Hexadecanoic acid isopropyl ester
Hexadecanoic acid
1-methylethyl ester
ISOPROPYL HEXADECANOATE
Deltyl
plymouthipp
ISOPROPYLPALMITAT
kesscoisopropylpalmitate
Isopal
Isopalm
Emcol-IP
estol103
ja-faipp
Hexadecanoic acid,1-methylethyl ester
Palmitic acid,isopropyl ester
Deltyl
Deltyl Prime
Emcol IP
Isopal
Isopropyl palmitate
Propal
Sinnoester PIT
Kessco IPP
Wickenol 111
Crodamol IPP
Emerest 2316
Isopalm
Stepan D 70
Isopropyl hexadecanoate
Nikkol IPP
IPP
1-Methylethyl hexadecanoate
Exceparl IPP
Estol 1517
IPP-EX
Palmsurf IPP 98
Lexol IPP
NSC 69169
Versagel MP 1600
Stepan IPP
Neoderm IPP
Nikkol IPP-EX
SR Crodamol IPP-LQ
IPP-R
Radia 7732




ISOPROPYL SALICYLATE
cas no 607-85-2 Salicylic acid isopropyl ester; Isopropyl o-hydroxybenzoate; 2-Hydroxybenzoic acid 1-methylethyl ester;
ISOPROPYL STEARATE
propan-2-yl octadecanoate; ISOPROPYL STEARATE, N° CAS : 112-10-7, Nom INCI : ISOPROPYL STEARATE, Nom chimique : Isopropyl stearate, N° EINECS/ELINCS : 203-934-9. Ses fonctions (INCI): Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Emollient : Adoucit et assouplit la peau.Agent d'entretien de la peau : Maintient la peau en bon état. Noms français : ESTER ISOPROPYLIQUE DE L'ACIDE STEARIQUE; STEARATE D'ISOPROPYLE. Noms anglais : ISOPROPYL STEARATE; OCTADECANOIC ACID, 1-METHYLETHYL ESTER; OCTADECANOIC ACID, ISOPROPYL ESTER; STEARIC ACID, ISOPROPYL ESTER. Utilisation et sources d'émission: Produit organique. 112-10-7 [RN] 203-934-9 [EINECS] Isopropyl stearate [ACD/IUPAC Name] Isopropylstearat [German] [ACD/IUPAC Name] MFCD00026666 Octadecanoic acid, 1-methylethyl ester [ACD/Index Name] Stéarate d'isopropyle [French] [ACD/IUPAC Name] [112-10-7] 10/7/112 1-METHYLETHYL OCTADECANOATE 4-02-00-01219 [Beilstein] 4-02-00-01219 (Beilstein Handbook Reference) [Beilstein] 7/10/112 EINECS 203-934-9 https://mcule.com/MCULE-3731648811 isopropyl octadecanoate Octadecanoic acid 1-methylethyl ester octadecanoic acid isopropyl ester Octadecanoic acid, isopropyl ester Octadecanoic acid,1-methylethyl ester propan-2-yl octadecanoate Revenge Stearic acid isopropyl ester Stearic acid, isopropyl ester Tegosoft S Wickenol 127
ISOPROPYLAMINE
SYNONYMS 2-Aminopropane; Monoisopropylamine; MIPA 2-Propanamine; sec-Propylamine; Propan-2-Amine; CAS NO. 75-31-0
Isopropylamine (MIPA)
2-Aminopropane; Monoisopropylamine; MIPA ; -Propanamine; sec-Propylamine; Propan-2-Amine; 2-Amino-propaan (Dutch); 2-amino-propano (Italian); 2-aminopropan (German); Isopropilamina (Italian); Isopropilamina (Spanish); Isopropylamine (French); cas no: 75-31-0
Isopropylethanolamine (IPAE)
2-(Diisopropylamino)ethanol; 2-Diisopropylaminoethanol; (Diisopropylamino)ethanol; N,N-Diisopropyl ethanolamine cas no: 96-80-0
ISOPROPYLPARABEN
2-ETHYLHEXYL DIPHENYL PHOSPHATE; Diphenyloctylphosphate; Diphenyl phosphate, 2-ethyl-1-hexanol ester; 2-ethylhexyl diphenyl phosphorate; diphenyl 2-ethylhexyl phosphate; Ethylhexyl diphenylphosphate; octicizer; Phosphoric acid 2-ethylhexyl diphenyl ester; santicize CAS NO:1241-94-7
Isoquinoline
sec-Propyl bromide; 2-Bromopropane; iso-C3H7Br; 2-Brompropan; 2-bromo-propan;bromo-2propane; 2-BROMOPROPANE; propane,2-bromo-; sec-propylbromide; ISOPROPYL BROMIDE; PropylBromide~98%;sec-Propyl bromide CAS NO:75-26-3
ISOSTEARETH-10
ISOSTEARETH-20, N° CAS : 52292-17-8 Nom INCI : ISOSTEARETH-20 Classification : Composé éthoxylé Ses fonctions (INCI) Agent émulsifiant : Favorise la formation de mélanges intimes entre des liquides non miscibles en modifiant la tension interfaciale (eau et huile) Tensioactif : Réduit la tension superficielle des cosmétiques et contribue à la répartition uniforme du produit lors de son utilisation
ISOSTEARETH-20
ISOSTEARIC ACID; 16-METHYLHEPTADECANOIC ACID; Isooctadecanoic acid CAS Number 2724-58-5
ISOSTEARIC ACID


Isostearic acid is a type of fatty acid that is often used in the cosmetics and personal care industry.
Isostearic acid is derived from the hydrogenation of isostearic acid-rich oils, typically plant-based oils.
Isostearic acid has a similar chemical structure to stearic acid but with a branched chain, which gives it some unique properties.
The chemical formula for isostearic acid is C18H36O2, and its IUPAC (International Union of Pure and Applied Chemistry) name is 2,2,4-trimethylpentanoic acid.

CAS Number: 30399-84-9
EC Number: 250-705-4



APPLICATIONS


Isostearic acid is commonly used as an emollient in skincare products, such as moisturizers and lotions, to provide skin with a soft and smooth feel.
Isostearic acid serves as a key ingredient in lip balms and lipsticks, helping to improve the texture and spreadability of these products.
Isostearic acid is utilized in the formulation of sunscreens to enhance their water resistance and adherence to the skin.

Isostearic acid is an essential component in stick deodorants, contributing to their firm texture and ease of application.
In hair care products like conditioners, isostearic acid helps in providing a silky and manageable texture to the hair.
Isostearic acid is often found in cream-based foundations, helping to create a creamy and blendable consistency.
Isostearic acid is used in body butters and creams, offering long-lasting hydration to the skin.

In mascara formulations, it aids in the even distribution of pigments, preventing clumping.
Isostearic acid plays a role in stabilizing emulsions in cosmetic products, ensuring that oil and water components remain well mixed.
Isostearic acid can be used in the production of solid soaps, contributing to their hardness and durability.
Isostearic acid is employed in the manufacturing of bar soaps to create a luxurious lather and improve the overall texture.

Isostearic acid is used in shaving creams to provide a smooth glide for razors.
Isostearic acid can be found in anti-aging creams, helping to lock in moisture and reduce the appearance of fine lines and wrinkles.
Isostearic acid is used in some pharmaceutical preparations for its emollient properties, aiding in the formulation of topical medications.
In cosmetic serums, isostearic acid can help improve the even distribution of active ingredients.

Isostearic acid is utilized in body washes and shower gels to enhance their lathering properties.
Isostearic acid is employed in the production of solid perfumes, providing a stable base for fragrance.
In lip glosses, it helps create a glossy and smooth finish.
Isostearic acid can be added to nail polishes to enhance their consistency and shine.
Isostearic acid is used in certain personal lubricants to provide a smooth and silky feel.

In hair styling products like pomades, isostearic acid contributes to the product's texture and hold.
Isostearic acid is found in some pharmaceutical ointments to aid in their spreadability and absorption.

Isostearic acid is used in the production of cuticle creams and balms to moisturize and nourish nail cuticles.
In foot creams and balms, it helps soften and hydrate rough and dry skin.
Isostearic acid is a versatile ingredient that finds applications in a wide range of cosmetic and personal care products, contributing to their texture, stability, and overall performance.

Isostearic acid is used in the production of lipstick pencils and crayons, providing them with a smooth and creamy texture for easy application.
Isostearic acid is found in some anti-chafing products, like anti-chafing balms, to reduce friction and irritation on the skin.

Isostearic acid is employed in the formulation of matte makeup products, such as matte foundations and powders, to create a velvety, shine-free finish.
In body scrubs and exfoliating products, it can help bind abrasive particles together and improve their spreadability.
Isostearic acid is used in some mineral makeup formulations, enhancing the adherence of mineral pigments to the skin.
Isostearic acid plays a role in the production of solid stick concealers, aiding in their smooth application and blendability.

In cream eyeshadows, isostearic acid helps create a creamy consistency and prevents creasing.
Isostearic acid is used in the manufacture of solid perfumed body balms, providing a solid base for fragrances.

Isostearic acid is employed in the formulation of waterproof mascaras to ensure they resist smudging and flaking.
In body lotions and creams with shimmer or glitter, it helps disperse the reflective particles evenly for a radiant glow.

Isostearic acid is used in certain specialty hair products, such as hair waxes and pomades, to provide hold and control without a greasy feel.
Isostearic acid can be found in cuticle oils and serums, aiding in the hydration and nourishment of nail cuticles.
Isostearic acid is used in the production of color-correcting makeup products to create a smooth and blendable texture.

In sunless tanning lotions and creams, isostearic acid helps distribute the tanning agent evenly for a streak-free tan.
Isostearic acid is added to some cosmetic primers to improve the overall texture of the skin before makeup application.
Isostearic acid is used in certain under-eye concealers and treatments to provide a smooth and hydrating formula.

In massage oils, it can be used to improve slip and glide during massages.
Isostearic acid is employed in some baby care products, such as baby lotions and diaper creams, to provide gentle moisturization.
Isostearic acid is used in certain specialty balms designed to soothe and protect sensitive areas of the skin.

In body powders, it helps create a smooth and easily applicable formula.
Isostearic acid is employed in some natural and organic cosmetics as an alternative to synthetic emollients.
Isostearic acid is added to certain nail treatments to help strengthen and condition nails.
In specialty skincare products, it can aid in the even distribution of active ingredients for targeted treatments.

Isostearic acid is used in some tattoo aftercare products to moisturize and protect the skin.
Isostearic acid's versatility extends to various niche cosmetic and personal care products, contributing to their functionality and appeal.
Isostearic acid is utilized in the production of solid stick blushes and bronzers, providing a creamy consistency for easy blending.
Isostearic acid can be found in some specialty face masks, contributing to their smooth texture and ease of application.
Isostearic acid is used in the formulation of tinted lip balms to offer both color and hydration to the lips.

In certain nail polishes, it aids in preventing chipping and provides a glossy finish.
Isostearic acid is employed in cuticle creams to soften and moisturize the cuticles around the nails.
Isostearic acid is added to some body sprays to disperse fragrance evenly on the skin.
Isostearic acid is used in sun care products like sunblock sticks, helping to create a water-resistant barrier on the skin.

In certain wound care products, it aids in creating a protective and moisturizing layer over wounds.
Isostearic acid can be found in natural and organic cosmetics as an emollient option with a plant-derived origin.
Isostearic acid is used in the formulation of face serums to enhance the skin's ability to absorb active ingredients.

In massage creams and lotions, it helps maintain smooth glide during massages.
Isostearic acid is employed in the production of solid stick eye treatments to reduce puffiness and dark circles.
In some aftershave products, it contributes to a soothing and moisturizing post-shave experience.
Isostearic acid can be found in certain hand creams and lotions designed to hydrate and protect the hands.

Isostearic acid is used in specialty products for tattoo care, aiding in the healing process and preservation of tattoo colors.
In foot balms and creams, it helps soften and moisturize dry and calloused skin.
Isostearic acid is added to some body wash bars to create a rich lather and improve their cleansing properties.
Isostearic acid is employed in hair pomades to provide a strong hold with a matte finish.

In lip stain formulations, it aids in creating long-lasting color that adheres to the lips.
Isostearic acid is used in some men's grooming products, such as beard balms, to condition facial hair.
Isostearic acid can be found in nail treatments to improve the overall health and appearance of nails.

Isostearic acid is added to some specialty face powders to create a finely milled texture for a flawless complexion.
In cuticle conditioners, it helps repair and protect the nail cuticles from damage.
Isostearic acid is employed in some solid hair conditioners to provide deep hydration without a heavy feel.
In certain intimate care products, it contributes to a gentle and moisturizing formula.

Isostearic acid is used in the production of solid stick highlighters to create a smooth and blendable texture for highlighting the face.
Isostearic acid can be found in some specialty lip scrubs, aiding in the exfoliation of dry and chapped lips.
Isostearic acid is employed in makeup setting sprays to help set makeup in place and provide a long-lasting finish.

In certain hair serums and oils, it contributes to a lightweight and non-greasy formula that adds shine and controls frizz.
Isostearic acid is used in sun care products such as sunblock sticks to ensure even coverage and sun protection.
Isostearic acid can be added to specialty eyeshadow primers to improve the adherence and vibrancy of eyeshadow pigments.

Isostearic acid is employed in the formulation of solid stick blushes and bronzers, enhancing their blendability and longevity.
In certain wound care products, it helps create a moisture-retentive environment to facilitate the healing process.
Isostearic acid is used in the production of solid stick face cleansers for convenient and mess-free cleansing.

Isostearic acid is found in certain cuticle pens designed for easy and precise application.
In hair styling waxes, it provides a pliable hold for shaping and styling hair.
Isostearic acid can be added to body scrubs to create a creamy base that enhances exfoliation.
Isostearic acid is employed in solid perfumed balms, providing a longer-lasting fragrance option.

In some natural and organic baby care products, it serves as an emollient option for gentle moisturization.
Isostearic acid is used in nail polish removers to help dissolve and remove nail polish effectively.
Isostearic acid can be found in makeup remover wipes to help lift and dissolve makeup residues.

In certain hand sanitizers, it contributes to a formula that moisturizes the hands while disinfecting.
Isostearic acid is employed in foot masks to hydrate and soften the skin on the feet.
Isostearic acid can be added to facial cleansing bars for a gentle cleansing experience.

In eyebrow waxes and gels, it helps shape and tame unruly eyebrows.
Isostearic acid is used in solid perfume compacts for easy and precise application of fragrance.
Isostearic acid can be found in some specialty cuticle creams enriched with vitamins and botanical extracts.

In body butters and balms, it helps create a rich and nourishing formula for dry skin.
Isostearic acid is employed in certain acne spot treatments to provide a non-drying and gentle formula.
Isostearic acid is used in specialty facial masks to improve the texture and spreadability of the mask.



DESCRIPTION


Isostearic acid is a type of fatty acid that is often used in the cosmetics and personal care industry.
Isostearic acid is derived from the hydrogenation of isostearic acid-rich oils, typically plant-based oils.
Isostearic acid has a similar chemical structure to stearic acid but with a branched chain, which gives it some unique properties.
The chemical formula for isostearic acid is C18H36O2, and its IUPAC (International Union of Pure and Applied Chemistry) name is 2,2,4-trimethylpentanoic acid.

Isostearic acid is classified as a saturated fatty acid because it lacks double bonds between carbon atoms in its hydrocarbon chain.
Isostearic acid is known for its ability to act as a thickening agent, emollient, and stabilizer in various cosmetic and personal care products, such as creams, lotions, and lipsticks.

Due to its branched structure, isostearic acid has a lower melting point compared to straight-chain fatty acids like stearic acid.
This property makes Isostearic acid useful for formulating products with desirable textures and spreadability.
Additionally, it can help improve the stability and shelf life of certain cosmetic formulations.

Isostearic acid is a saturated fatty acid with a branched molecular structure.
Isostearic acid is derived from the hydrogenation of certain plant-based oils.
Isostearic acid compound is also known as 2,2,4-trimethylpentanoic acid.

Isostearic acid is commonly used in the cosmetics and personal care industry.
Isostearic acid serves as an emollient, providing moisturization to the skin.
Its unique structure gives it a lower melting point than straight-chain fatty acids.
Isostearic acid acts as a thickening agent in various skincare and makeup products.
Isostearic acid helps improve the spreadability of creams and lotions.

Isostearic acid enhances the texture and feel of lipsticks and other cosmetic formulations.
Isostearic acid is often utilized to stabilize emulsions in cosmetics.
Isostearic acid contributes to the long-term stability of certain cosmetic products.
Isostearic acid is generally recognized as safe for topical use.

Isostearic acid is used in both water-in-oil and oil-in-water emulsions.
Its branched chain structure provides flexibility and versatility in formulation.
Isostearic acid can be found in moisturizers, sunscreens, and foundation products.
Isostearic acid is compatible with a wide range of other cosmetic ingredients.

Isostearic acid can help prevent products from separating over time.
Isostearic acid is valued for its ability to create creamy and smooth textures.
Isostearic acid is often used to improve the consistency of stick deodorants.

Isostearic acid may also be used in hair care products like conditioners.
Isostearic acid is odorless and typically does not impact the scent of cosmetic products.
Isostearic acid is considered non-comedogenic and suitable for sensitive skin.
Isostearic acid can be used in both leave-on and rinse-off cosmetic formulations.

Isostearic acid is important for achieving desired product aesthetics.
Its versatility and safety make it a popular choice in the cosmetics industry.



PROPERTIES


Chemical Formula: C18H36O2
IUPAC Name: 2,2,4-Trimethylpentanoic acid
Molecular Weight: Approximately 284.48 grams per mole
Physical State: Solid at room temperature
Appearance: Typically a white to off-white crystalline powder
Odor: Odorless
Solubility: Insoluble in water; soluble in organic solvents like ethanol and oils.
Melting Point: Generally in the range of 45-55°C (113-131°F)
Boiling Point: Decomposes before boiling.
Density: Approximately 0.88 grams per cubic centimeter (g/cm³)
Acid Value: A measure of its acidity due to carboxylic acid groups.
Hydrophilic-Lipophilic Balance (HLB): Typically considered more lipophilic (oil-loving).
Emollient: It acts as an emollient, providing moisturization and softening to the skin.
Thickening Agent: Used as a thickening agent in cosmetic formulations.
Stabilizer: It can stabilize emulsions, preventing separation of oil and water phases.
Texture Enhancer: Improves the texture and spreadability of cosmetic products.
Spreadability: Enhances the even distribution of pigments and active ingredients.
Long-Lasting: Contributes to the long-term stability and shelf life of products.
Hydration: Helps lock in moisture and prevents dehydration of the skin.



FIRST AID


Inhalation:

If isostearic acid fumes or dust are inhaled, remove the affected person from the contaminated area to an area with fresh air.
If breathing difficulties persist, seek immediate medical attention.
Provide artificial respiration if the person is not breathing, and if trained to do so.


Skin Contact:

In case of skin contact, immediately remove contaminated clothing and shoes.
Wash the affected skin area thoroughly with plenty of lukewarm water and mild soap for at least 15 minutes.
Seek medical attention if skin irritation, redness, or rash develops.


Eye Contact:

If isostearic acid comes into contact with the eyes, rinse the affected eye(s) gently with lukewarm water for at least 15 minutes, keeping the eyelid(s) open.
Seek immediate medical attention if eye irritation, redness, or pain persists.


Ingestion:

If isostearic acid is ingested accidentally, do not induce vomiting unless directed to do so by medical professionals.
Rinse the mouth with water if the material is not oil-based or emulsified.
Seek immediate medical attention and provide the medical personnel with information about the ingested substance.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When handling isostearic acid, wear appropriate PPE, including safety goggles or a face shield, gloves, and a lab coat or protective clothing.
The selection of PPE should be based on the specific hazards and conditions of use.

Ventilation:
Ensure adequate ventilation in the handling area to prevent the buildup of vapors or dust.
Use local exhaust ventilation or work in well-ventilated areas.

Avoid Inhalation:
Avoid inhaling fumes or dust from isostearic acid.
If handling the material in powder form, consider wearing a dust mask or respirator as needed.

Avoid Skin Contact:
Minimize skin contact with isostearic acid.
In case of skin contact, wash affected areas promptly with soap and water.

Eye Protection:
Wear safety goggles or a face shield to protect your eyes from potential splashes or contact with isostearic acid.

Handling Equipment:
Use appropriate handling equipment, such as scoops or spatulas, to transfer isostearic acid from containers to avoid skin contact.

No Smoking or Open Flames:
Do not smoke or use open flames in areas where isostearic acid is handled, as it may be flammable.


Storage:

Container Selection:
Store isostearic acid in containers made of materials compatible with fatty acids, such as high-density polyethylene (HDPE) or stainless steel.
Ensure that the containers are tightly sealed to prevent contamination and moisture ingress.

Temperature Control:
Store isostearic acid in a cool, dry place away from direct sunlight and heat sources.
The storage temperature should typically be within a range of 15°C to 30°C (59°F to 86°F).

Avoid Incompatible Materials:
Keep isostearic acid away from incompatible materials, such as strong oxidizing agents and strong bases, as well as incompatible chemicals.
Store it separately from these substances.

Moisture Control:
Protect isostearic acid from exposure to moisture and humidity, as water can lead to hydrolysis or degradation of the material.
Store it in a moisture-free environment.

Labeling:
Clearly label storage containers with the product name, hazard information, and handling instructions.
Maintain clear identification of the contents to prevent confusion.

Storage Stability:
Check the manufacturer's recommendations for the shelf life and storage conditions of the specific isostearic acid product you are using.
Follow any storage stability guidelines provided.

Fire Safety:
If the material is flammable, store it away from open flames, sparks, and ignition sources.
Ensure that fire extinguishing equipment is available in the storage area.

Spill Containment:
Have spill containment measures in place, including absorbent materials and spill response equipment, to handle any accidental spills or leaks promptly.

Keep Out of Reach:
Store isostearic acid out of reach of children and unauthorized personnel.

Regulatory Compliance:
Comply with all relevant local, state, and national regulations regarding the handling, storage, and transportation of isostearic acid.


Transportation:

When transporting isostearic acid, follow all applicable regulations for hazardous materials, if applicable.
Ensure proper labeling and packaging in accordance with transportation regulations.
Use suitable containers and secure them to prevent spills or leaks during transportation.
Be aware of any special handling or transportation requirements specified by regulatory authorities.



SYNONYMS


2,2,4-Trimethylpentanoic acid
Isooctanoic acid
2,2,4-Trimethylvaleric acid
Isopentanoic acid, 2,2,4-trimethyl-
2,2,4-Trimethyl-n-pentanoic acid
2,2,4-Trimethylvaleric acid
TMVA (Abbreviation for 2,2,4-Trimethylpentanoic acid)
Isotridecyl alcohol
2,2-Dimethylpentanoic acid
2,2-Dimethylvaleric acid
Isoheptanoic acid
2,2-Dimethyl-n-pentanoic acid
2,2-Dimethylvaleric acid
Neododecanoic acid
2,2-Dimethylheptanoic acid
2,2-Dimethyl-n-heptanoic acid
2,2-Dimethyl-n-valeric acid
Isoheptylic acid
2,2-Dimethyl-n-octanoic acid
2,2-Dimethyl-n-nonanoic acid
Isododecanoic acid
2,2-Dimethyl-n-decanoic acid
2,2-Dimethyl-n-undecanoic acid
2,2-Dimethyl-n-dodecanoic acid
Isoarachidic acid
2,2-Dimethyl-n-tetradecanoic acid
2,2-Dimethyl-n-hexadecanoic acid
2,2-Dimethyl-n-octadecanoic acid
Isotetradecyl alcohol
2,2-Dimethylpentadecanoic acid
2,2-Dimethylheptadecanoic acid
2,2-Dimethyloctadecanoic acid
ISOSTEARIC ACID

Isostearic acid is a branched-chain fatty acid derived from oleic acid.
Isostearic acid is characterized by its branched structure, which differs from the linear structure of most common fatty acids.

CAS Number: 22890-21-7
EC Number: 679-818-0

Synonyms: Isomerized fatty acid, Branched-chain fatty acid, Isomerized oleic acid, Branched-chain oleic acid, 2-Methylundecanoic acid, 2-Methyldecanoic acid, 2-Methylundecylic acid, 2-Methyldecylic acid, 2-Methylundecanoate, 2-Methyldecylate, 2-Methylundecylate, 2-Methyldecylate, 2-Methyl-10-undecanoic acid, 2-Methyldecanoate, 2-Methylundecyl ester, 2-Methyldecyl ester, 2-Methyl-10-undecanoate, Isostearate, Isomerized oleate, Branched-chain oleate, Isomerized oleoyl acid, Isomerized oleyl acid, Branched-chain oleyl acid, Branched-chain oleoyl acid, Isomerized 9-octadecenoic acid, Isomerized cis-9-octadecenoic acid, Isomerized 9-octadecylic acid, Isomerized cis-9-octadecylic acid, Isomerized 9-octadecenoate, Isomerized cis-9-octadecenoate, Isomerized 9-octadecyl ester, Isomerized cis-9-octadecyl ester



APPLICATIONS


Isostearic acid is widely used in the cosmetics industry for its versatile applications.
Isostearic acid is a common ingredient in skincare products such as lotions, creams, and moisturizers.

Isostearic acid acts as an emollient, helping to soften and hydrate the skin.
Isostearic acid is valued for its ability to create smooth and creamy textures in cosmetic formulations.

Isostearic acid is often used in lip balms and lipsticks to provide moisture and enhance spreadability.
In hair care products, it helps to condition and tame unruly hair, reducing frizz and improving manageability.

Isostearic acid contributes to the stability of emulsions in creams and lotions, preventing separation of oil and water phases.
Isostearic acid can act as a thickening agent, providing viscosity to cosmetic formulations without feeling heavy or greasy.
Isostearic acid is compatible with a wide range of cosmetic ingredients, allowing for versatile formulation possibilities.

Isostearic acid helps to improve the spreadability and absorption of skincare products, ensuring even application and maximum efficacy.
Isostearic acid is often found in sunscreens, providing emollient properties while enhancing the dispersion of UV filters.

In makeup products, it helps to create smooth and blendable textures in foundations, concealers, and eyeshadows.
Isostearic acid can be used in natural and organic cosmetics as a skin-friendly alternative to synthetic emollients.

Isostearic acid contributes to the overall sensory experience of cosmetic products, imparting a luxurious feel and texture.
Isostearic acid is valued for its non-comedogenic properties, making it suitable for use in products for acne-prone skin.

Isostearic acid helps to improve the stability and shelf life of cosmetic formulations, reducing the risk of rancidity and spoilage.
Isostearic acid is used in baby care products such as diaper creams and lotions for its gentle and soothing properties.
In men's grooming products, it helps to soften facial hair and moisturize the skin after shaving.

Isostearic acid is often included in anti-aging creams and serums for its hydrating and plumping effects on the skin.
Isostearic acid can be used in natural deodorants as an alternative to synthetic emulsifiers, providing moisture and odor control.

Isostearic acid contributes to the overall performance and efficacy of cosmetic formulations, ensuring optimal results for the consumer.
In massage oils and body butters, it helps to nourish and hydrate the skin, leaving it soft and supple.

Isostearic acid can be used in exfoliating scrubs and cleansers to provide moisture and prevent dryness.
Isostearic acid is often found in baby oils and lotions for its gentle and hypoallergenic properties, suitable for sensitive skin.
Isostearic acid is a versatile ingredient with numerous applications in the cosmetics industry, valued for its emollient, thickening, and stabilizing properties.

Isostearic acid is commonly used in the formulation of facial cleansers and makeup removers for its ability to dissolve and lift away dirt, oil, and makeup.
Isostearic acid is a key ingredient in shaving creams and foams, providing lubrication and glide for a smooth shave while moisturizing the skin.

Isostearic acid is utilized in body washes and shower gels to create a rich lather that cleanses and hydrates the skin.
In hand creams and lotions, it helps to replenish moisture lost from frequent washing and exposure to harsh environmental conditions.
Isostearic acid is incorporated into foot creams and balms to soften calluses and soothe dry, cracked heels.

Isostearic acid can be found in cuticle oils and treatments, helping to nourish and condition the nails and cuticles.
Isostearic acid is used in sunless tanning products to enhance the spreadability and absorption of the tanning agent, ensuring a streak-free tan.

In lip scrubs and exfoliators, it helps to gently buff away dead skin cells while moisturizing and conditioning the lips.
Isostearic acid is added to bath oils and bath bombs to create a luxurious bathing experience, leaving the skin soft and hydrated.

Isostearic acid is included in anti-itch creams and lotions to provide relief from dry, irritated skin conditions such as eczema and psoriasis.
Isostearic acid is utilized in barrier creams and ointments to protect the skin from irritation and friction, particularly in sensitive areas.

In baby wipes and diaper rash creams, it helps to soothe and protect delicate skin from diaper rash and irritation.
Isostearic acid can be found in massage oils and lotions used in spa treatments, providing nourishment and hydration to the skin.

Isostearic acid is added to cuticle creams and treatments to soften and moisturize the cuticles, promoting healthy nail growth.
Isostearic acid is used in body scrubs and exfoliating treatments to slough off dead skin cells and reveal smoother, more radiant skin.

In foot scrubs and treatments, it helps to soften rough, dry skin and calluses, leaving feet feeling soft and refreshed.
Isostearic acid is incorporated into face masks and treatments to hydrate and nourish the skin, promoting a healthy, glowing complexion.

Isostearic acid can be found in hand sanitizers and antibacterial gels to moisturize and protect the skin from dryness and irritation.
Isostearic acid is added to cuticle oils and serums to hydrate and strengthen the nails, preventing breakage and splitting.

In body oils and serums, it helps to lock in moisture and nourish the skin, leaving it feeling soft and supple.
Isostearic acid is utilized in facial toners and mists to hydrate and refresh the skin, restoring its natural balance.

Isostearic acid can be found in makeup setting sprays and primers to create a smooth, even base for makeup application while providing hydration.
Isostearic acid is added to body lotions and creams to replenish moisture and soothe dry, rough skin.

In cuticle creams and treatments, it helps to soften and moisturize the cuticles, promoting healthy nail growth.
Isostearic acid is used in bath salts and soaks to soften the skin and relax tired muscles, providing a luxurious bathing experience.


Isostearic acid is compatible with a wide range of cosmetic ingredients, allowing for versatile formulation possibilities.
Isostearic acid functions as a co-emulsifier, assisting primary emulsifiers in stabilizing oil-in-water and water-in-oil emulsions.
Isostearic acid is often found in lip balms, body lotions, and facial creams, providing nourishment and protection.

Its emulsifying properties make it useful in formulating creams and lotions with high oil content.
Isostearic acid helps create smooth and uniform textures in cosmetic products, enhancing their application and absorption.

Isostearic acid contributes to the overall performance and stability of skincare and personal care formulations.
Isostearic acid is known for its ability to improve the spreadability and blending of makeup products.

In hair care, it helps reduce frizz and static while enhancing shine and manageability.
Isostearic acid is often used in natural and organic cosmetics for its skin-friendly properties.
Its mild and non-irritating nature makes it suitable for use in products for sensitive skin types.

Isostearic acid contributes to the luxurious feel and sensory experience of high-quality cosmetic formulations.
Isostearic acid is a versatile ingredient valued for its emollient, surfactant, and thickening properties in skincare and personal care products.



DESCRIPTION


Isostearic acid is a branched-chain fatty acid derived from oleic acid.
Isostearic acid is characterized by its branched structure, which differs from the linear structure of most common fatty acids.
Isostearic acid is used in various cosmetic and personal care products as an emollient, surfactant, and thickening agent due to its unique properties.

Isostearic acid is a branched-chain fatty acid derived from oleic acid.
Its unique structure features branching at the carbon chain, distinguishing it from linear fatty acids.

Isostearic acid is typically a white to pale yellow solid at room temperature, with a slightly waxy texture.
Isostearic acid is soluble in organic solvents like ethanol and acetone but insoluble in water.
Isostearic acid is valued in cosmetics for its emollient properties, which help soften and moisturize the skin.

Isostearic acid acts as a surfactant, allowing it to stabilize emulsions and disperse ingredients in cosmetic formulations.
As a thickening agent, it contributes to the viscosity and consistency of creams, lotions, and other skincare products.

Isostearic acid can be synthesized from oleic acid through isomerization or dimerization processes.
In addition to skincare, it is used in hair care products for its conditioning and smoothing effects.

Isostearic acid plays a role in improving the spreadability and texture of cosmetic formulations.
Its mild and gentle properties make it suitable for sensitive skin formulations.
Isostearic acid helps enhance the sensory experience of cosmetic products, imparting a luxurious feel.
This fatty acid contributes to the long-lasting hydration and moisturization of the skin.



PROPERTIES


Physical Properties:

Appearance: White to off-white solid or waxy substance
Odor: Generally odorless or has a faint, characteristic odor
Melting Point: Typically between 45°C to 55°C
Boiling Point: Decomposes before reaching a boiling point
Density: Approximately 0.9 to 0.95 g/cm^3
Solubility in Water: Insoluble
Solubility in Organic Solvents: Soluble in organic solvents such as ethanol, acetone, and chloroform
pH: Not applicable (as it is a solid)


Chemical Properties:

Chemical Formula: C18H36O2
Molar Mass: Approximately 284.48 g/mol
Hydrogen Bond Acceptor Count: 2
Hydrogen Bond Donor Count: 1
Rotatable Bond Count: 16
Complexity: 179
Isomeric SMILES: CCC(CCC(C)(C)CCCCCC(C)C)CCCCC(O)=O
Topological Polar Surface Area: 37.3 Ų
Refractive Index: Typically around 1.450-1.460
Flash Point: Typically above 100°C (closed cup)
Vapor Pressure: Negligible at room temperature
Octanol/Water Partition Coefficient (Log P): Approximately 8.35



FIRST AID


1. Inhalation:

If inhaled, remove the affected person to fresh air immediately.
Keep the individual calm and at rest.
If breathing is difficult, administer oxygen if trained to do so.
Seek medical attention if symptoms persist or worsen.


2. Skin Contact:

Remove contaminated clothing and footwear immediately.
Wash the affected area with soap and water thoroughly for at least 15 minutes.
If irritation or rash develops, seek medical advice.
If skin irritation persists, seek medical attention.


3. Eye Contact:

Flush the eyes with gently flowing lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention and bring the product container or label if available.


4. Ingestion:

Rinse the mouth thoroughly with water if the product has been swallowed.
Do not induce vomiting unless directed by medical personnel.
Do not give anything by mouth to an unconscious person.
Seek medical attention or contact a poison control center immediately.


5. Notes to Physician:

No specific antidote is available.
Treat symptomatically and supportively.
In case of skin burns, treat as thermal burns.
Monitor vital signs and provide appropriate medical care as necessary.


6. Advice to First Aid Providers:

Ensure that personal protective equipment (PPE) is worn when providing first aid.
Follow standard precautions for handling chemical exposures.
Provide comfort and reassurance to the affected individual.
If symptoms persist or worsen, seek medical advice promptly.



HANDLING AND STORAGE


1. Handling:

Handle isostearic acid in a well-ventilated area to minimize inhalation exposure.
Use appropriate personal protective equipment (PPE) such as safety goggles, gloves, and protective clothing to prevent skin and eye contact.
Avoid breathing vapors, mist, or dust generated during handling.
Do not eat, drink, or smoke while handling isostearic acid.
Wash hands thoroughly after handling to remove any residual product.
Prevent skin and eye contact by avoiding splashing and spills.


2. Storage:

Store isostearic acid in a cool, dry, well-ventilated area away from heat, sparks, and open flames.
Keep containers tightly closed when not in use to prevent contamination and evaporation.
Store away from incompatible materials such as strong oxidizing agents.
Do not store near sources of ignition or in direct sunlight.
Ensure storage area is equipped with appropriate containment measures to contain spills.
Maintain good housekeeping practices to minimize the risk of accidental exposure.
Store in containers made of compatible materials, such as high-density polyethylene (HDPE) or glass.
Check containers regularly for signs of damage or leakage and replace if necessary.
Follow all applicable regulations and guidelines for the safe storage of chemicals.


3. Transportation:

Transport isostearic acid in accordance with applicable regulations for the transport of hazardous materials.
Ensure containers are securely sealed and properly labeled with appropriate hazard warnings.
Use suitable packaging materials to prevent breakage or leakage during transportation.
Avoid transportation with incompatible materials or substances that may react with isostearic acid.


4. Spill and Leak Procedures:

In case of spillage, contain the spill to prevent further spread and minimize exposure.
Wear appropriate PPE, including gloves and safety goggles, during cleanup.
Absorb spilled liquid with inert absorbent material (e.g., sand, earth) and collect in suitable containers for disposal.
Avoid creating dust or aerosols during cleanup by using dampened materials.
Dispose of contaminated materials in accordance with local regulations and guidelines.
Clean spill area thoroughly with soap and water to remove any residue.


5. Waste Disposal:

Dispose of unused or contaminated isostearic acid in accordance with local, state, and federal regulations.
Follow appropriate waste disposal procedures and guidelines for chemical waste.
Do not dispose of via sewerage systems or in domestic waste.
Consult with regulatory authorities or waste disposal experts for proper disposal methods.
Empty containers may be recycled or disposed of in accordance with applicable regulations.


6. Emergency Procedures:

Familiarize yourself and your staff with emergency procedures in case of spills, leaks, or exposure incidents.
Maintain emergency eyewash stations and safety showers in areas where isostearic acid is handled.
Keep a spill kit and absorbent materials readily available for immediate response to spills.
Train personnel on proper handling procedures and emergency response protocols.
ISOSTEARIC ACID
Isostearic acid is a fatty acid molecule with an 18-carbon atom chain backbone.
Isostearic Acid is an isomer of stearic acid
Isostearic Acid's chemical formula is C18H36O2


CAS NUMBER: 2724-58-5

EC NUMBER: 250-178-0

MOLECULAR FORMULA: C18H36O2

MOLECULAR WEIGHT: 284.5 g/mol

IUPAC NAME: 16-methylheptadecanoic acid




While stearic acid has a linear carbon chain with 18 carbon atoms, isosteric acid as a carbon chain with 17 atoms and a single carbon branch at the 16th carbon atom.
Isostearic Acid's chemical structure can be represented as (CH3)2CH(CH2)14CO2H.

Isostearic Acid is found naturally in meat products and vegetable oils.
Isostearic acid has a wide range of industrial uses.

Isostearic Acid is mainly used as an additive in adhesives or lubricants for both paints
Isostearic Acid can be used in personal care products.

Being a fatty acid, Isostearic Acid is also amphiphilic
Isostearic Acid is a molecule with a hydrophobic end and a hydrophilic end.

As such, Isostearic Acid can have favorable interactions with both polar and non-polar molecules, enabling it to act as a surfactant.
Isostearic Acid is also soluble in many oils, which allows it to be used as an emulsifier or dispersant.

With this set of properties, isostearic acid is a useful additive in a variety of applications, including:
-Adhesives
-Coatings and paints
-Finishing agents
-Lubricants
-Sealants
-Solvents
-Surfactants
-Viscosity adjusters

Isostearic Acid is used in personal care products
Isostearic Acid is also used in cosmetic industry

Isostearic Acid has lubricating or adhesive properties
Isostearic Acid is also used in paper products.

Isostearic Acid is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst
There is no chemical addition in this reaction, Isostearic Acid is based 100% on the parent oil or fat.

Isostearic acid is used in applications which require a liquid fatty acid with exceptional stability: thermal stability in the case of a lubricant, odour stability for a cosmetic formulation, and oxidation stability for products with long shelf-life requirements.
The branching structure of isostearic acid also enhances its dispersing power

Isostearic Acid is used in cosmetic and industrial applications for the stabilisation of pigments and mineral particles in oils and solvents.
Isostearic Acid is used for a cosmetic formulations

Isostearic Acid can be used in industrial applications for the stabilisation of pigments mineral particles in oils and solvents
Isostearic Acid differs from other C18 fatty acids of the same category in a number of ways.

While other C18 fatty acids are produced by splitting fats or oils, isostearic acid is manufactured as a coproductof a tightly controlled reaction to synthesize dimerized fatty acids.
The structural makeup of isostearic acid also has a valuable combination of saturation and branching, when compared to other fatty acids like stearic acid and oleic acid.

This set of features make isostearic acid a versatile building block for high-value applications in synthetic lubricants, metal stamping and forming, coatings, and personal care products.
Isostearic Acid's features impart thermal stability, oxidative stability, surface activity, lubricity, low color, and feel in multiple formulations. Isostearic acid is used as-is in some cases, but is also derivatized to form isostearyl alcohols, amides, and esters to further expand its reach across many industries and applications.

APPLICATIONS:
*Synthetic lubricants – Isostearic Acid has good thermal and oxidative stability

*Lubricant additives – Isostearic Acid is derivatized to isostearyl amide to provide boundary lubrication and detergency

*Coatings – Isostearic Acid imparts flexibility and durability properties to industrial coatings

*Metalworking – Isostearic Acid has good surface activity for protective coatings and thermal stability for rolling and stamping

*Personal care products – Isostearic Acid is derivatized to isostearyl alcohol to impart feel and texture to creams and lotions.


Isostearic Acid is a unique fatty acid.
Isostearic Acid combines the best properties of stearic acid with the best properties of oleic acid.

Isostearic acid is an 18-carbon branched-chain fatty acid naturally found in plants and animals.
However, Isostearic Acid's a blend of many octadecanoic acids, found in vegetables and animals fat.

Isostearic Acid is prepared from soybean oil and tallow.
Isostearic Acid comes as white to pale yellow, clear oily liquid.

Isostearic Acid is liquid at room temperature.
Isostearic Acid is chemically, a carboxyl group attached to alkyl chain, methylated, branched at various carbons makes it much more stable compared to other linear chain fatty acids, including oxidation potential.

Isostearic Acid can be used as a lubricant, that can improve flow of a powder mixture.
Isostearic Acid has excellent spreadability without oiliness


PHYSICAL PROPERTIES:

-Molecular Weight: 284.5 g/mol

-XLogP3: 7.2

-Exact Mass: 284.271530387 g/mol

-Monoisotopic Mass: 284.271530387 g/mol

-Topological Polar Surface Area: 37.3Ų

-Physical Description: Colorless Liquid

-Boiling Point: 400 °C

-Melting Point: 69.5 °C

-Solubility: 0.007116 mg/L

-LogP: 7.674

-Refractive Index: 1.4440 (estimate)

-Storage Temperature: 2-8°C

-pka: 4.78


Isostearic Acid can be easily used in a cosmetic which not only moisturizes skin but also does not leave any oily feel.
However, in cosmetic formulation Isostearic Acid is used as a binder to form cake-like compact powder or eye shadow.

Isostearic Acid is also used in cleansing and emulsifying agent, because of presence of both ionic and nonionic groups.
Isostearic Acid is used in varieties of cosmetic and personal care products.


CHEMICAL PROPERTIES:

-Hydrogen Bond Donor Count: 1

-Hydrogen Bond Acceptor Count: 2

-Rotatable Bond Count: 15

-Heavy Atom Count: 20

-Formal Charge: 0

-Complexity: 212

-Isotope Atom Count: 0

-Defined Atom Stereocenter Count: 0

-Undefined Atom Stereocenter Count: 0

-Defined Bond Stereocenter Count: 0

-Undefined Bond Stereocenter Count: 0

-Covalently-Bonded Unit Count: 1

-Compound Is Canonicalized: Yes


Isostearic Acid is a synthetically created fatty acid
Isostearic Acid is used as a binder in skin and beauty products

Although Isostearic Acid is also seen in products as a surfactant and emulsifier
Isostearic Acid is used to thicken most formulas as a binder and emulsifier.

As a fatty acid, Isostearic Acid is a component of a complex mixture that also has the added benefit of protecting the skin from oxidative damage
Isostearic Acid is used to thicken most formulas as a binder and emulsifier.

Isostearic Acid is a clear, oily liquid that is used in a wide variety of cosmetics and personal care products.
Isostearic acid (16-Methylheptadecanoic acid) is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.

Isostearic acid is a fatty acid that is used as an emollient in pharmaceutical preparations.
Isostearic acid has been shown to have skin-moisturizing and anti-inflammatory properties, which are due to its ability to inhibit the activity of phospholipase A2.

Isostearic acid also has a high degree of chemical stability and adsorption capacity.
Isostearic Acid's adsorption mechanism is not yet well understood, but it appears to be related to its hydroxyl group.

Isostearic Acid has been used successfully in the treatment of congestive heart failure and can prevent the accumulation of lipids on the surface of blood vessels, thereby reducing atherosclerosis.
Isostearic Acid also functions as a substrate for the synthesis of isovaleric acid, which can be used as a fragrance ingredient in cosmetic products.

Isostearic Acid is a fatty acid which contains 18-carbon atom chain.
The IUPAC name of Isostearic Acid is octadecanoic acid.

Isostearic Acid is used in the following products:
-washing & cleaning products
-adhesives and sealants
-fuels
-lubricants and greases
-coating products
-fertilisers

Isostearic Acid is used in biocides (e.g. disinfectants, pest control products)
Isostearic Acid is also used in pH regulators and water treatment products

Isostearic Acid can be used in laboratory chemicals, plant protection products, water softeners and water treatment chemicals.
Isostearic Acid is used in formulation of mixtures
Isostearic Acid is used for the manufacture of chemicals.

Isostearic Acid is a yellow solution and its chemical formula is C18H36O2.
Isostearic Acid is a saturated carbon solution.

Isostearic Acid is found naturally in meat products and vegetable oils.
The molecular mass of Isostearic Acid is 284.48 g/mol.

Isostearic Acid is soluble in many oils and is used as an emulsifier or dispersant.
Isostearic Acid acid is a methyl-branched fatty acid

Isostearic Acid is heptadecanoic acid (margaric acid) substituted by a methyl group at position 16.
Isostearic Acid is a branched-chain saturated fatty acid

Isostearic Acid is a long-chain fatty acid
Isostearic Acid is functionally related to a heptadecanoic acid.
Isostearic Acid is a natural product found in Aristolochia grandiflora, Streptomyces, and other organisms with data available.


SYNONYMS:

ISOOCTADECANOIC ACID
isostearic
16-METHYLHEPTADECANOIC ACID
Isostearinsure
ISOSTEARIC ACID
16-methyl-heptadecanoicaci
Heptadedecanoicacid,16-Methyl
ISOSTEARIC ACID MIXED ISOMERS
Heptadecanoic acid, 16-methyl-
heptadecanoic acid, 16-methyl-
jaric I-18CG
jaric I-18IG
jaric I-18LG
liponate ISA
16-methyl heptadecanoic acid
16-methyl margaric acid
16-methylheptadecanoic acid
isooctadecanoic acid
prisorine 3505
prisorine 3515
isostearicacid
ISOSTEARIC ACID
Isooctadecanoic acid
16-METHYLHEPTADECANOIC ACID
2724-58-5
30399-84-9
Prisorine 3509
Heptadecanoic acid, 16-methyl-
16-methyl margaric acid
16-methyl-heptadecanoic acid
LZM5XA0ILL
CHEBI:84896
(+)-Isostearic acid
UNII-LZM5XA0ILL
EINECS 220-336-3
16-methylmargaric acid
EMERSOL 873
SCHEMBL15489
CHEMBL1865303
DTXSID1040790
16-METHYLHEPTADECANOICACID
LMFA01020014
HY-W127433
NCGC00164392-01
NCGC00164392-02
NCGC00255115-01
AS-57253
CAS-30399-84-9
CS-0185665
Isostearic acid
16-Methylheptadecanoic acid
220-336-3
250-178-0
2724-58-5
30399-84-9
Heptadecanoic acid, 16-methyl-
Isooctadecanoic acid
MFCD00044082
MI3875000
X33R8U0062
(+)-isostearic acid
16-methyl margaric acid
16-methyl-heptadecanoic acid
16-methylmargaric acid
2-methyl-heptadecanoic acid
2-Methylheptadecanoic acid
Heptadecanoic acid, 2-methyl-
λ-Isostearic acid


ISOSTEARIC ACID
Empirical Formula (Hill Notation): C18H36O2
CAS Number: 2724-58-5
Molecular Weight: 284.48



APPLICATIONS


Isostearic acid (16-Methylheptadecanoic acid) is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.

Isostearic acid can be used as adhesion/cohesion promoter.
Further, Isostearic acid is used as coalescing agent.

In various industries, Isostearic acid can be used as emulsifier.

Isostearic acid can be used as chemical intermediate.
Furthermore, Isostearic acid is used in lubricants and lubricant additives
Isostearic acid is used as lubricating agent.

Isostearic acid is used in monomers.
Isostearic acid can be used as opacifer.

Isostearic acid can be used as softener and conditioner.
Further, Isostearic acid can be used as surface modifier.
Isostearic acid is used as surfactant (surface active agent).

Isostearic acid is used as swelling agent.
More to that, Isostearic acid can be used as coalescing agent.
Isostearic acid can be used as emulsifier.

Isostearic acid can be used as lubricating agent.
Moreover, Isostearic acid can be used as thickening agent.
Isostearic acid has industrial applications for the stabilisation of pigments mineral particles in oils and solvents.

Being a fatty acid, Isostearic acid is also amphiphilic, meaning it is a molecule with a hydrophobic end and a hydrophilic end.
As such, Isostearic acid can have favorable interactions with both polar and non-polar molecules, enabling it to act as a surfactant.

Isostearic acid is also soluble in many oils, which allows it to be used as an emulsifier or dispersant.
With this set of properties, Isostearic acid is a useful additive in a variety of applications.

Isostearic acid can be used as adhesives.
Moreover, Isostearic acid is used as coatings and paints.

Isostearic acid can be used as finishing agents.
Further, Isostearic acid can be used as lubricants.
Isostearic acid is used as sealants.

Isostearic acid can be used as solvents.
More to that, Isostearic acid is used as surfactants.
Isostearic acid is used as viscosity adjusters.

Isostearic acid is derived from renewable sources, offering unique characteristics such as high oxidation resistance and excellent cold temperature properties.
Applications of Isostearic acid include additives or base stock for the fuel and lubricants industry and emollients for personal care.

Isostearic acid is an exceptionally mild liquid fatty acid that offers a light lubricious feel and can be used in many skin care and colour cosmetic applications.
Furthermore, Isostearic acid also offers film forming properties, making it ideal for use in soaps, shaving foams and liquid cleansers.

Isostearic acid is used in bath, shower & soaps
Moreover, Isostearic acid is used in antiperspirants & deodorants

Isostearic acid is used in after sun products
Further, Isostearic acid is used in body care products
Isostearic acid is used for face / neck skin care

Isostearic acid is used for face colour products
Furthermore, Isostearic acid is used for hair colour products
Isostearic acid can be used for lip colour products

Isostearic acid can be used for shaving / hair removal products
More to that, Isostearic acid can be used for sun protection products
Isostearic acid is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst there is no chemical addition in this reaction, isostearic acid is based 100% on the parent oil or fat.

Isostearic acid is used in applications which require a liquid fatty acid with exceptional stability:

Thermal stability in the case of a lubricant
Odour stability for a cosmetic formulation
Oxidation stability for products with long shelf-life requirements

The branching structure of Isostearic acid also enhances its dispersing power, and it is used in cosmetic and industrial applications for the stabilisation of pigments and mineral particles in oils and solvents.
Super Refined Isostearic Acid is a vegetable-derived liquid fatty acid that offers a light lubricious skin feel, preventing a dry afterfeel from topical products.

Isostearic acid promotes low viscosity for good spreading and acts as a cleansing agent, emollient and superfatting agent and is compatible with cold processing.
Recommended topical usage levels of Isostearic Acid is 0.5-5%.

Isostearic acid is a useful synthetic intermediate.
Further, Isostearic acid is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.

Isostearic acid (16-Methylheptadecanoic acid) is used in the synthesis of methyl-branched poly(hydroxyalkanoate)s, biosurfactants and silver nanoparticles.



DESCRIPTION


Isostearic acid is a methyl-branched fatty acid that is heptadecanoic acid (margaric acid) substituted by a methyl group at position 16.
Further, Isostearic acid is a branched-chain saturated fatty acid, a long-chain fatty acid and a methyl-branched fatty acid.

Isostearic acid is functionally related to a heptadecanoic acid.

Isostearic acid is a lightly-branched, liquid fatty acid produced by the reaction of oleic acid with a natural mineral catalyst – there is no chemical addition in this reaction, isostearic acid is based 100% on the parent oil or fat.
Moreover, Isostearic acid is used in applications which require a liquid fatty acid with exceptional stability. Isostearic acid has thermal stability in the case of a lubricant.
Isostearic acid has odour stability for a cosmetic formulation.

Isostearic acid has oxidation stability for products with long shelf-life requirements.
The branching structure of Isostearic acid also enhances its dispersing power, and it is used in cosmetic and industrial applications for the stabilisation of pigments and mineral particles in oils and solvents.

Isostearic acid is a fatty acid molecule with an 18-carbon atom chain backbone.
Furthermore, Isostearic acid is an isomer of stearic acid, meaning that they both have a chemical formula of C18H36O2, but differ in the arrangement of their atoms.
While stearic acid has a linear carbon chain with 18 carbon atoms, Isostearic acid as a carbon chain with 17 atoms and a single carbon branch at the 16th carbon atom.

The chemical structure of Isostearic acid can be represented as (CH3)2CH(CH2)14CO2H.
Isostearic acid is found naturally in meat products and vegetable oils.

Isostearic acid has a wide range of industrial uses.
More to that, Isostearic acid is mainly used as an additive in adhesives or lubricants for both paints and personal care products.

The slight structural difference between Isostearic acid and its isomer, stearic acid, changes the physical state at room temperature and pressure.
Although stearic acid is solid, Isostearic acid is a clear yellow liquid.

This is because the branching nature of Isostearic acid’s carbon chain makes the molecules unable to pack as efficiently in the solid state as in the non-branching stearic acid.
Less efficient packing of Isostearic acid relatively lowers the melting point.

Some other basic properties of Isostearic acid include:

Molecular mass: 284.48 g/mol
Density (at 25°C): 0.89 g/cm3

Being a fatty acid, Isostearic acid is also amphiphilic, meaning it is a molecule with a hydrophobic end and a hydrophilic end.
As such, Isostearic acid can have favorable interactions with both polar and non-polar molecules, enabling it to act as a surfactant.

Isostearic acid is also soluble in many oils, which allows it to be used as an emulsifier or dispersant.

With this set of properties, Isostearic acid is a useful additive in a variety of applications, including:

Adhesives
Coatings and paints
Finishing agents
Lubricants
Sealants
Solvents
Surfactants
Viscosity adjusters

Isostearic acid differs from other C18 fatty acids of the same category in a number of ways.
While other C18 fatty acids are produced by splitting fats or oils, Isostearic acid is manufactured as a coproductof a tightly controlled reaction to synthesize dimerized fatty acids.
The structural makeup of Isostearic acid also has a valuable combination of saturation and branching, when compared to other fatty acids like stearic acid and oleic acid.

This set of features make Isostearic acid a versatile building block for high-value applications in synthetic lubricants, metal stamping and forming, coatings, and personal care products.
Isostearic acid’s features impart thermal stability, oxidative stability, surface activity, lubricity, low color, and feel in multiple formulations.
Isostearic acid is used as-is in some cases, but is also derivatized to form isostearyl alcohols, amides, and esters to further expand its reach across many industries and applications.

Take a closer look at some of the applications for Isostearic acid produced from tall oil fatty acid (TOFA):

Synthetic lubricants – Isostearate ester base oils with good thermal and oxidative stability
Lubricant additives – As-is and derivatized to isostearyl amide to provide boundary lubrication and detergency
Coatings – Impart flexibility and durability properties to industrial coatings
Metalworking – Good surface activity for protective coatings and thermal stability for rolling and stamping
Personal care products – As-is and derivatized to isostearyl alcohol to impart feel and texture to creams and lotions.

Isostearic acid offers a powerful combination of performance, renewability, steady supply, and short lead times, from a domestic producer.
Furthermore, Isostearic acid is our unique, highly branched, saturated fatty acid.

Isostearic acid has some features that are transparent and odorless, unlike straight chain fatty acids. Additionally, Isostearic acid has excellent heat stability, oxidation resistance, pigment dispensing ability, defoaming property and is compatible with various organic solvents.

Isostearic acid is a liquid fatty acid created from oleic acid.
More to that, Isostearic acid is claimed to have great odour, thermal and oxidation stability and is great for the stabilization of pigments and mineral particles in oils and solvents.
Isostearic acid is quite popular in foundations.



PROPERTIES


Form: powder
Functional group: carboxylic acid
Storage temp.: 2-8°C
Molecular Weight: 284.5
XLogP3: 7.2
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 15
Exact Mass: 284.271530387
Monoisotopic Mass: 284.271530387
Topological Polar Surface Area: 37.3 Ų
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 212
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Acid Value, mgKOH/g: 180 to 195
Relative Density, @d20/20: 0.881
Viscosity, C.P.S, @25°C: 35 to 60
Saponification Value: 190 to 200
Iodine Value, gI2/100g: 15 max
Cloud Point, °C: 10 max



FIRST AID


If inhaled:

If breathed in, move person into fresh air.
If not breathing, give artificial respiration.

In case of skin contact:

Wash off with soap and plenty of water.

In case of eye contact:

Flush eyes with water as a precaution.

If swallowed:

Never give anything by mouth to an unconscious person.
Rinse mouth with water.

Indication of any immediate medical attention and special treatment needed:
No data available



HANDLING AND STORAGE


Precautions for safe handling:

Advice on protection against fire and explosion:
Provide appropriate exhaust ventilation at places where dust is formed.
Normal measures for preventive fire protection.

Conditions for safe storage, including any incompatibilities:

Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.

Storage stability:

Recommended storage temperature: 2 - 8 °C
Storage class (TRGS 510): 13: Non Combustible Solids

Storage:

Containers of Isostearic acid may be hazardous when empty since they retain product residues (vapors, liquid).
Do not store Isostearic acid at a temperature exceeding 80 °c.

Observe all warnings and precautions listed for Isostearic acid.
Outside or detached storage is recommended.
Polymerization or oxidation of the unsaturated bonds may occur.

Store Isostearic acid in a dry, cool, well-ventilated area.
Store Isostearic acid in the dark.
Use only containers, joints, pipes, etc., made in a material suitable for use with fatty acids.



SYNONYMS


ISOSTEARIC ACID
Isooctadecanoic acid
heptadecanoic acid, 16-methyl-
jaric I-18CG
jaric I-18IG
jaric I-18LG
liponate ISA
16-methyl heptadecanoic acid
16-methyl margaric acid
16-methylheptadecanoic acid
isooctadecanoic acid
prisorine 3505
prisorine 3515
isostearicacid
16-METHYLHEPTADECANOIC ACID
2724-58-5
30399-84-9
Prisorine 3509
Heptadecanoic acid, 16-methyl-
16-methyl margaric acid
16-methyl-heptadecanoic acid
16-methyl-heptadecanoicaci
Heptadedecanoicacid,16-Methyl
isostearic
ISOSTEARIC ACID
ISOOCTADECANOIC ACID
ISOSTEARIC ACID MIXED ISOMERS
16-METHYLHEPTADECANOIC ACID
Heptadecanoic acid, 16-methyl-
LZM5XA0ILL
Isostearic acid
16-Methylheptadecanoic acid [ACD/IUPAC Name]
16-Methylheptadecansäure [German] [ACD/IUPAC Name]
220-336-3 [EINECS]
250-178-0 [EINECS]
2724-58-5 [RN]
30399-84-9 [RN]
Acide 16-méthylheptadécanoïque [French] [ACD/IUPAC Name]
Heptadecanoic acid, 16-methyl- [ACD/Index Name]
Isooctadecanoic acid
MFCD00044082 [MDL number]
MI3875000
X33R8U0062
(+)-isostearic acid
16-methyl margaric acid
16-methyl-heptadecanoic acid
16-methylmargaric acid
2-methyl-heptadecanoic acid
2-Methylheptadecanoic acid
Heptadecanoic acid, 2-methyl-
λ-Isostearic acid
CHEBI:84896
(+)-Isostearic acid
UNII-LZM5XA0ILL
EINECS 220-336-3
16-methylmargaric acid
DSSTox_CID_7963
EMERSOL 873
DSSTox_RID_78624
DSSTox_GSID_27963
SCHEMBL15489
CHEMBL1865303
DTXSID1040790
16-METHYLHEPTADECANOICACID
ZINC4556536
Tox21_302276
LMFA01020014
HY-W127433
NCGC00164392-01
NCGC00164392-02
NCGC00255115-01
AS-57253
Isostearic acid, >=97% (capillary GC)
CAS-30399-84-9
CS-0185665
C20356
D92986
J-016709
W-109211
Q27158161
16-Methylheptadecanoic acid





ISOSTEARIC ACID (ISAC)

Isostearic acid (ISAC) is a type of fatty acid that is derived from the isomerization of oleic acid.
Oleic acid is a monounsaturated omega-9 fatty acid commonly found in various vegetable oils.
Isostearic acid (ISAC) undergoes a process called isomerization, which changes its molecular structure.

CAS Number: 30399-84-9
EC Number: 250-178-0

Isostearic acid, Branched stearic acid, Isomerized oleic acid, Oleic acid isomers, Modified stearic acid, Isostearate, Oleate isomers, Branched-chain fatty acid, Isomerized fatty acid, Oleic acid derivatives, Isomeric stearate, Modified oleic acid, Altered stearic acid, Isomerized triglyceride, Oleate mixture, Isostearic acid blend, Isomeric lipid, Branched-chain triglyceride, Oleic acid analogs, Isomer-rich fatty acid, Oleic acid isomerization product, Altered lipid chain, Modified triglyceride, Isomer-enriched stearate, Oleate derivative, Branched fatty acid chain, Isostearic acid complex, Oleic acid structural variant, Isomerized lipid fraction, Altered stearate ester, Isostearate blend, Oleic acid homologs, Branched-chain lipid, Isomeric triglyceride, Oleate complex, Isomer-rich fatty acid blend, Modified oleate, Altered fatty acid chain, Isomerized stearate ester, Oleic acid isomer blend, Branched stearate derivative, Isostearic triglyceride, Oleate isomer mixture, Isomeric fatty acid complex, Modified stearate ester, Altered triglyceride, Isomer-enriched oleate, Oleic acid analog mixture, Branched-chain stearate, Isostearate homologs, Oleate structural variant, Isomerized fatty acid blend, Altered lipid ester, Modified oleic acid fraction, Isomer-rich stearate, Oleic acid isomer fraction, Branched triglyceride, Isostearate isomer blend



APPLICATIONS


Isostearic acid (ISAC) is commonly used in the cosmetic industry for its emollient properties, contributing to the smooth and moisturizing feel of skincare products.
In the formulation of lip balms and lipsticks, isostearic acid enhances product texture and aids in providing a comfortable application.
The altered molecular structure of isostearic acid makes it a valuable ingredient in sunscreen formulations, improving the spreadability and feel of the product on the skin.

Isostearic acid (ISAC) is utilized in the production of emulsions and creams, where its compatibility with other ingredients enhances stability and texture.
Skincare lotions often contain isostearic acid to provide a silky and non-greasy finish upon application.
Isostearic acid is employed in the development of high-quality facial creams, contributing to their luxurious texture and moisturizing capabilities.

The lubricating properties of isostearic acid make it suitable for certain industrial applications, including in the production of lubricants and specialty oils.
Hair care products such as conditioners and styling creams may incorporate isostearic acid to improve manageability and provide a soft touch.

Isostearic acid (ISAC) finds use in the pharmaceutical industry for its role in formulating topical medications, contributing to their skin-friendly properties.
Deodorants and antiperspirants benefit from the addition of isostearic acid, enhancing the product's glide during application.

Isostearic acid (ISAC) is utilized in the creation of high-performance foundations and concealers, contributing to their blendability and long-lasting wear.
The modified triglyceride composition of isostearic acid makes it a suitable ingredient in the production of bath oils and shower gels, providing a pleasant skin-feel.

Isostearic acid (ISAC) contributes to the stability of cosmetic emulsions, preventing phase separation and ensuring a consistent product texture.
Moisturizing body lotions often contain isostearic acid to impart a soft and velvety feel to the skin.

Isostearic acid (ISAC) is incorporated into makeup primers to enhance the smooth application and adherence of subsequent cosmetic products.
The versatile nature of isostearic acid makes it suitable for use in a variety of personal care formulations, from hand creams to body butters.
Sunscreen sprays benefit from the addition of isostearic acid, which helps disperse the active ingredients evenly for optimal sun protection.

Isostearic acid (ISAC) is employed in the production of massage oils, contributing to their glide and overall skin-friendly properties.
The compatibility of isostearic acid with a range of ingredients makes it a preferred choice in the formulation of anti-aging creams and serums.

Isostearic acid (ISAC) is utilized in the creation of hydrating facial mists, providing a refreshing and moisturizing experience.
Certain cosmetic powders, such as setting powders and blushes, may contain isostearic acid to improve adherence to the skin.

Isostearic acid (ISAC) contributes to the development of long-wearing and transfer-resistant cosmetic products, including lipsticks and eyeliners.
Isostearic acid (ISAC) is a key component in the formulation of cuticle creams and nail care products, promoting nail health and hydration.

Isostearic acid (ISAC) is used in the production of specialty soaps, contributing to their lathering properties and skin-feel.
The application of isostearic acid extends beyond cosmetics, finding use in various industrial and pharmaceutical formulations due to its unique chemical properties.

Isostearic acid (ISAC) is employed in the textile industry as a lubricating agent during the processing of fibers, enhancing their smoothness.
Leather conditioners often contain isostearic acid to impart suppleness and a soft touch to leather goods.
Isostearic acid (ISAC) is utilized in the production of adhesive formulations, contributing to the adhesive's viscosity and tackiness.

Certain industrial coatings and paints may incorporate isostearic acid to improve the flow and leveling properties of the coating.
Isostearic acid (ISAC) is used in the creation of specialty inks, enhancing their compatibility with various printing processes.
The water-resistant properties of isostearic acid make it valuable in the formulation of waterproof coatings for outdoor fabrics.

Isostearic acid (ISAC) is applied in the manufacturing of candles, contributing to the even burning and smooth texture of the wax.
Some food products utilize isostearic acid as a food-grade lubricant, especially in the production of confectionery items.

Isostearic acid (ISAC) finds use in the development of rust preventatives and corrosion inhibitors for metal surfaces.
In the production of anti-fogging agents for eyewear and mirrors, isostearic acid contributes to the prevention of condensation.

Isostearic acid (ISAC) is employed in the creation of specialty detergents and cleaning formulations for its surfactant properties.
The film-forming characteristics of isostearic acid make it a valuable component in certain cosmetic products, such as mascaras.

Isostearic acid (ISAC) is used in the formulation of biodegradable lubricants, contributing to environmentally friendly industrial applications.
In the manufacturing of candles, isostearic acid aids in controlling the melting point and improving the overall burn quality.

Isostearic acid (ISAC) is applied in the production of mold-release agents, facilitating the release of molded products from molds.
Certain polymer formulations incorporate isostearic acid to modify the rheological properties and improve processing.

Isostearic acid (ISAC) is utilized in the creation of specialty waxes, contributing to their hardness and melting characteristics.
The water-repellent nature of isostearic acid makes it valuable in the formulation of water-resistant coatings for paper and cardboard.

Isostearic acid (ISAC) is employed in the creation of personal lubricants for its smooth and non-irritating properties.
The solubility of isostearic acid in various solvents makes it suitable for use in the formulation of inkjet printing inks.

Isostearic acid (ISAC) is used in the production of metalworking fluids, providing lubrication and cooling properties during machining.
In the textile industry, isostearic acid is applied as a softening agent for fabrics to enhance their feel and drape.

Isostearic acid (ISAC) is utilized in the formulation of biodegradable hydraulic fluids for certain industrial applications.
The low-temperature properties of isostearic acid make it suitable for use in the creation of cold-weather lubricants.
Isostearic acid (ISAC) is applied in the development of specialty coatings for electronic components, providing protection against environmental factors.

Isostearic acid (ISAC) is utilized in the production of biodegradable and eco-friendly lubricants, reducing environmental impact.
Isostearic acid (ISAC)'s ability to enhance the stability of formulations makes it valuable in the creation of long-lasting perfumes.
The modified structure of isostearic acid contributes to its use in the production of bio-based plastics.

Isostearic acid (ISAC) finds application in the development of specialty greases for specific industrial machinery.
In the pharmaceutical industry, isostearic acid is used as an excipient in the formulation of certain drug delivery systems.

Isostearic acid (ISAC) is incorporated into the production of candle wax melts, enhancing their fragrance release and texture.
The water-repellent properties of isostearic acid make it useful in the formulation of water-resistant wood finishes.

Isostearic acid (ISAC) is employed in the creation of biodegradable hydraulic fluids, particularly in environmentally sensitive areas.
The lubricating qualities of isostearic acid find application in the production of wire drawing compounds for metalworking processes.
Isostearic acid (ISAC) is used as a key component in the manufacturing of eco-friendly, biodegradable detergents.
Isostearic acid (ISAC) contributes to the formulation of environmentally conscious and sustainable personal care products.

Isostearic acid (ISAC) is employed in the creation of non-toxic, bio-based ink formulations for printing applications.
The compatibility of isostearic acid with various polymers makes it valuable in the production of bio-based polymer blends.

Isostearic acid (ISAC) is used in the formulation of biodegradable cutting fluids for metal machining processes.
Isostearic acid is applied in the creation of eco-friendly textile softeners, reducing environmental impact.
The modified triglyceride composition of isostearic acid makes it suitable for use in the production of eco-friendly soap bases.

Isostearic acid (ISAC) contributes to the formulation of biodegradable and sustainable industrial cleaners.
Isostearic acid (ISAC) is used in the development of environmentally friendly, biodegradable paint additives.
The compatibility of isostearic acid with various solvents makes it useful in the creation of bio-based ink formulations.

Isostearic acid (ISAC) is employed in the production of bio-based, sustainable anti-corrosion coatings for metals.
Isostearic acid (ISAC) finds application in the creation of bio-based and eco-friendly release agents for molded products.
The altered molecular structure of isostearic acid makes it valuable in the production of sustainable and biodegradable plasticizers.

Isostearic acid (ISAC) is used in the formulation of bio-based and environmentally friendly metalworking coolants.
Isostearic acid (ISAC) contributes to the development of bio-based and eco-friendly drilling fluids for certain industrial applications.
The versatility of isostearic acid extends to the production of sustainable and biodegradable lubricating oils for various machinery.



DESCRIPTION


Isostearic acid (ISAC) is a type of fatty acid that is derived from the isomerization of oleic acid.
Oleic acid is a monounsaturated omega-9 fatty acid commonly found in various vegetable oils.
Isostearic acid (ISAC) undergoes a process called isomerization, which changes its molecular structure.

The isomerization process results in a mixture of branched-chain isomers of stearic acid.
Stearic acid is a saturated fatty acid with an 18-carbon chain.
Isostearic acid, due to its branched structure, often exhibits different properties compared to its straight-chain counterparts.

Isostearic acid (ISAC) finds applications in the cosmetic and personal care industry, where it is used in the formulation of various products such as skin creams, lotions, and cosmetics.
Isostearic acid (ISAC) is valued for its emollient properties, providing moisturization and a smooth feel to the skin.
Additionally, Isostearic acid (ISAC) is used in the production of certain surfactants and lubricants.

Isostearic acid (ISAC) is a modified fatty acid derived from the isomerization of oleic acid.
The isomerized form of oleic acid gives rise to isostearic acid, featuring a branched molecular structure.
As a branched-chain fatty acid, Isostearic acid (ISAC) exhibits distinct chemical properties compared to its linear counterparts.

Isostearic acid (ISAC) is commonly used in cosmetic formulations for its emollient properties.
The isomerization process imparts unique characteristics to isostearic acid, making it suitable for various applications in the personal care industry.
Derived from natural sources, Isostearic acid (ISAC) is often employed as a key ingredient in skin creams and lotions.

Isostearic acid (ISAC) contributes to the smooth texture and moisturizing effects of skincare products.
The altered molecular structure of isostearic acid enhances its compatibility with skin and other cosmetic ingredients.
Isostearic acid (ISAC) is known for its ability to form stable emulsions in cosmetic formulations.
This fatty acid is widely utilized in the production of lip balms and lipsticks for its skin-conditioning benefits.

Isostearic acid (ISAC) plays a role in improving the spreadability and sensory feel of cosmetic products.
Due to its modified structure, isostearic acid exhibits unique solubility characteristics in various formulations.
In the personal care industry, isostearic acid is favored for its versatility in creating aesthetically pleasing textures.

Isostearic acid (ISAC) is a common component in formulations designed to enhance the stability and shelf life of cosmetic products.
The isomer-rich nature of isostearic acid contributes to its efficacy in diverse skincare formulations.

Isostearic acid (ISAC) is often included in makeup products to provide a smooth and velvety finish.
The branched structure of isostearic acid contributes to its lubricating properties, making it suitable for certain industrial applications.

Isostearic acid (ISAC) is valued for its ability to enhance the spreadability of emulsions and creams.
The modified lipid chain of isostearic acid makes it a sought-after ingredient for formulating high-quality skincare products.
Cosmetic products containing isostearic acid are known for their improved adherence to the skin.

Isostearic acid (ISAC) is utilized in the development of sunscreen formulations to enhance the product's texture and application.
The altered triglyceride composition of isostearic acid allows for precise control over the consistency of cosmetic formulations.

Isostearic acid (ISAC) is compatible with a variety of cosmetic ingredients, contributing to the formulation of well-balanced products.
The isomer-enriched blends of isostearic acid are often chosen for their ability to provide a luxurious feel in skincare products.
Isostearic acid (ISAC) continues to be a key ingredient in the cosmetic industry, contributing to the innovation and effectiveness of various personal care formulations.



PROPERTIES


Chemical Formula: The chemical formula for isostearic acid is C18H36O2.
Molecular Weight: The molecular weight of isostearic acid is approximately 284.48 g/mol.
Structural Formula: Isostearic acid is characterized by a branched molecular structure due to the isomerization of oleic acid.
Physical State: Isostearic acid is generally found in the form of a colorless to pale yellow liquid at room temperature.
Odor: Isostearic acid may have a mild, characteristic odor.
Melting Point: The melting point of isostearic acid is around 35-40°C.
Boiling Point: The boiling point of isostearic acid is typically higher than its melting point, around 220-230°C.
Solubility: Isostearic acid is generally insoluble in water but soluble in organic solvents such as ethanol and ether.
Density: The density of isostearic acid is approximately 0.86 g/cm³.
Viscosity: Isostearic acid exhibits a moderate viscosity, contributing to its use in various formulations.
Refractive Index: The refractive index of isostearic acid is around 1.44.
Flash Point: Isostearic acid has a flash point above its boiling point, making it non-flammable.
pH: Isostearic acid is not typically associated with a specific pH value as it is often used in formulations where pH is adjusted by other ingredients.
Chemical Stability: Isostearic acid is generally stable under normal storage conditions.
Compatibility: Isostearic acid is compatible with a variety of cosmetic and industrial ingredients.



FIRST AID


Inhalation:

Move to Fresh Air:
Immediately move the affected person to an area with fresh air.

Provide Respiratory Support:
If the person has difficulty breathing, administer artificial respiration or use available respiratory support equipment.

Seek Medical Attention:
Contact emergency medical services for further evaluation and treatment.


Skin Contact:

Remove Contaminated Clothing:
Quickly and gently remove any contaminated clothing, including shoes, and rinse the affected skin.

Flush with Water:
Wash the affected skin thoroughly with plenty of water for at least 15 minutes.

Use Mild Soap:
Use a mild soap to cleanse the skin while rinsing, if available.

Seek Medical Attention:
If irritation, redness, or other symptoms persist, seek medical attention promptly.


Eye Contact:

Flush Eyes with Water:
Immediately flush the eyes with a gentle stream of lukewarm water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing.

Remove Contact Lenses:
If applicable, remove contact lenses during eye irrigation.

Seek Medical Attention:
Obtain prompt medical attention, even if the person feels relief, as further evaluation is essential.
Ingestion:

Do NOT Induce Vomiting:
Do not induce vomiting unless instructed to do so by medical professionals.

Rinse Mouth:
If the substance is swallowed, rinse the mouth with water.

Seek Medical Attention:
Contact emergency medical services or a poison control center for guidance and seek medical attention immediately.


General Advice:

Personal Protection:
Always wear appropriate personal protective equipment (PPE) when handling isostearic acid to prevent exposure.

Medical Attention:
Seek medical attention promptly for any signs of adverse effects, even if they appear minor.

Note to Healthcare Providers:
Provide healthcare providers with information about the substance for accurate diagnosis and treatment.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Always wear appropriate PPE, including gloves, protective eyewear, and suitable clothing, when handling isostearic acid.

Ventilation:
Work in a well-ventilated area or use local exhaust ventilation to minimize inhalation exposure.
Ensure adequate ventilation in confined spaces.

Avoid Contact:
Avoid skin and eye contact with isostearic acid.
In case of contact, follow the recommended first aid measures promptly.

Hygiene Practices:
Implement good hygiene practices, including regular hand washing, to prevent unintentional exposure.

Prevent Ingestion:
Avoid eating, drinking, or smoking in areas where isostearic acid is handled to prevent accidental ingestion.

Labeling:
Clearly label containers with the identity of the substance, relevant hazard information, and appropriate safety instructions.

Training:
Provide proper training to personnel handling isostearic acid, including information on potential hazards and proper emergency procedures.

Spill Response:
Have spill response procedures in place, including the use of absorbent materials and appropriate personal protective equipment.

Equipment Inspection:
Regularly inspect and maintain equipment used for handling isostearic acid to ensure proper functioning and prevent leaks.


Storage:

Storage Location:
Store isostearic acid in a cool, dry, and well-ventilated area, away from incompatible materials.

Temperature Control:
Keep storage temperatures within the recommended range to prevent product degradation or separation.

Avoid Sunlight:
Protect containers from direct sunlight or heat sources to prevent temperature fluctuations.

Separation:
If the isostearic acid is prone to separation, store it in a manner that allows for easy remixing if needed.

Container Integrity:
Ensure the integrity of storage containers to prevent leaks or spills.
Use containers made of compatible materials.

Segregation:
Segregate isostearic acid from incompatible materials, such as strong acids, bases, or oxidizing agents.

Fire Prevention:
Store away from ignition sources and follow fire prevention measures.

Controlled Access:
Restrict access to the storage area to authorized personnel only.

Emergency Equipment:
Keep emergency equipment, such as spill response kits and fire extinguishers, readily accessible.

Documentation:
Maintain proper documentation of storage conditions, including batch numbers, dates, and supplier information.

Compliance:
Adhere to local, regional, and national regulations regarding the storage of chemicals, including isostearic acid.
Isostearic acid
isostearic acid; steraric acid; ,isooctadecanoic acid; 16-METHYLHEPTADECANOIC ACID CAS NO: 2724-58-5
ISOSTEARYL ALCOHOL
cas no 27458-93-1 Isooctadecanol; 16-Methylheptadecan-1-ol; Isooctadecan-1-ol; Isooctadecyl alcohol; 1-Heptadecanol, 16-methyl-; Isooctadecylalcohol;
ISOSTEARYL GLYCOLATE
ISOSTEARYL LACTATE, N° CAS : 42131-28-2, Nom INCI : ISOSTEARYL LACTATE, Nom chimique : Isooctadecyl lactate, N° EINECS/ELINCS : 255-674-0 Compatible Bio (Référentiel COSMOS) Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent d'entretien de la peau : Maintient la peau en bon état
ISOSTEARYL ISOSTEARATE

Isostearyl isostearate is a chemical compound that belongs to the ester class.
Isostearyl isostearate is commonly used in the cosmetics and personal care industry as an emollient and skin-conditioning agent.
Isostearyl isostearate is derived from isostearyl alcohol and isostearic acid.
Isostearyl isostearate is known for its ability to improve the texture and feel of cosmetic products, providing a smooth and silky finish.

CAS Number: 41669-30-1
EC Number: 255-485-3

Isostearyl Isostearate, Isostearic Acid Isostearyl Ester, 2-Octyldodecyl Isostearate, Octyldodecyl Isostearate, Isostearyl Ester, Octyldodecyl Isostearate, Isostearate de 2-octyl-dodecyle, Octododecyl Isostearate, Isostearyl-2-octyldodecanoate, Isostearyl/Octyldodecyl Isostearate, Isostearyl Myristate, Isostearyl/Octyldodecyl Stearate, Isooctyl Isostearate, Isostearyl Alcohol Isostearic Acid Ester, 2-Octyldodecyl Isostearate, Isostearyl Isostearate Ester, Isostearyl Isostearate, Isooctyl Isostearate, Octododecyl Isostearate, Isostearyl Isostearate, Isostearate d'Isostearyl, Isostearyl Isostearate, Isooctyl Isostearate, Isostearate d'Isostearyl, 2-Octyldodecyl Isostearate, Isostearyl Isostearate Ester, Isostearate de 2-octyl-dodecyle, Isostearate d'Isostearyl, Isostearate de 2-octyl-dodecyle, Octododecyl Isostearate, Isostearyl Isostearate, Isostearate d'Isostearyl, Isostearyl Isostearate Ester, Octododecyl Isostearate, Isostearyl Ester, Isostearyl Isostearate, Isostearyl Isostearate Ester, Isostearate d'Isostearyl, Octyldodecyl Isostearate, Isostearyl Alcohol Isostearic Acid Ester, 2-Octyldodecyl Isostearate, Isostearate de 2-octyl-dodecyle, Isostearyl Isostearate Ester, Octododecyl Isostearate, Isostearyl/Octyldodecyl Stearate, Isostearyl Isostearate, Isooctyl Isostearate, Octododecyl Isostearate, 2-Octyldodecyl Isostearate, Isostearyl Alcohol Isostearic Acid Ester, Isostearyl Isostearate, Isostearyl Isostearate Ester, Isostearyl Isostearate, Isostearate de 2-octyl-dodecyle, Octyldodecyl Isostearate, Octyldodecyl Isostearate, Isostearyl Isostearate Ester, Isostearyl Ester, Isostearyl/Octyldodecyl Isostearate, 2-Octyldodecyl Isostearate, Octododecyl Isostearate, Isostearyl Isostearate, Isostearate d'Isostearyl.



APPLICATIONS


Isostearyl isostearate finds extensive use in cosmetic formulations as an emollient.
Isostearyl isostearate is commonly employed in skincare products such as creams and lotions for its skin-conditioning properties.
Isostearyl isostearate is a key ingredient in lip balms and lipsticks, contributing to their smooth and creamy textures.
Isostearyl isostearate is often included in foundations and concealers to enhance their spreadability and blendability.

In haircare products, this ester helps to condition and improve the texture of hair.
Its lubricating properties make it valuable in shaving creams, providing a smooth glide during shaving.
Isostearyl isostearate is used in sunscreens to enhance the even application and spread of the product.

Isostearyl isostearate is incorporated into anti-aging formulations for its moisturizing and skin-replenishing attributes.
Isostearyl isostearate is found in moisturizers, contributing to long-lasting hydration on the skin.
Isostearyl isostearate is utilized in cosmetic formulations for its ability to create a non-greasy finish.

In makeup products like eyeshadows and blushes, it aids in the even distribution and adherence to the skin.
Isostearyl isostearate is commonly present in body lotions, offering a luxurious and silky feel upon application.
Isostearyl isostearate is suitable for use in sensitive skin products due to its gentle nature.
Isostearyl isostearate is employed in skincare serums to enhance the delivery and absorption of active ingredients.

Isostearyl isostearate is used in deodorants for its skin-friendly and non-irritating characteristics.
Isostearyl isostearate is included in cosmetic formulations to improve the overall sensory experience.
Isostearyl isostearate contributes to the stability of emulsions and helps prevent the separation of oil and water phases.
Isostearyl isostearate is utilized in hair styling products to provide a smooth and manageable finish.

Isostearyl isostearate is a valuable component in waterproof makeup formulations, enhancing their durability.
In sunscreen formulations, it aids in the dispersion of UV filters and improves their efficacy.
Isostearyl isostearate is incorporated into facial cleansers and makeup removers for its gentle cleansing properties.
Isostearyl isostearate is used in baby care products such as diaper creams for its skin-soothing qualities.
Isostearyl isostearate is employed in cosmetic products for mature skin to address dryness and promote suppleness.

Isostearyl isostearate is utilized in body scrubs and exfoliating products to enhance their texture.
Isostearyl isostearate is versatile and compatible with various cosmetic ingredients, making it suitable for a wide range of applications.

Isostearyl isostearate serves as a key component in the formulation of facial masks, contributing to their smooth application and removal.
Isostearyl isostearate is commonly included in hand creams and lotions to provide a soft and moisturized feel to the skin.
Isostearyl isostearate is used in cosmetic primers to create a smooth base for makeup application.

Isostearyl isostearate is incorporated into body washes and shower gels to enhance their emollient properties.
In tinted moisturizers and BB creams, it helps achieve a natural and even coverage on the skin.

Isostearyl isostearate is utilized in cosmetic formulations for men's grooming products, such as aftershave lotions.
Isostearyl isostearate is found in anti-chafing products, contributing to friction reduction in sensitive areas.
Isostearyl isostearate is used in cuticle creams and nail care formulations to improve the texture and appearance of nails.

Isostearyl isostearate is employed in cosmetic powders to enhance the blending and adherence to the skin.
Isostearyl isostearate is utilized in massage oils, providing a smooth and gliding texture during massage.

In cosmetic sticks like lip balms and solid perfumes, it contributes to their easy and precise application.
Isostearyl isostearate is included in mattifying products to control excess shine on the skin's surface.
Isostearyl isostearate is used in cosmetic wipes and towelettes for its gentle and conditioning properties.

Isostearyl isostearate is a common ingredient in overnight masks and sleeping packs to promote skin hydration.
Isostearyl isostearate is found in body oils, contributing to their lightweight and non-greasy texture.
Isostearyl isostearate is utilized in cosmetic formulations for its role in improving the spreadability of pigments.

Isostearyl isostearate is included in cosmetic serums for its ability to create a smooth and velvety skin feel.
Isostearyl isostearate is found in cosmetic emulsions, helping to stabilize the mixture of water and oil components.
Isostearyl isostearate is incorporated into sunless tanning products for a streak-free and even application.
Isostearyl isostearate is used in cosmetic formulations for acne-prone skin due to its non-comedogenic nature.

Isostearyl isostearate is present in cosmetic mousse formulations, contributing to their lightweight and airy texture.
Isostearyl isostearate is used in cosmetic sticks for contouring and highlighting to ensure easy blending.
Isostearyl isostearate is included in cosmetic products for tattoo care to maintain skin suppleness and prevent dryness.

Isostearyl isostearate is utilized in cosmetic products for individuals with eczema or sensitive skin conditions.
Isostearyl isostearate is employed in cosmetic formulations for its role in enhancing the overall aesthetics and user experience of the product.

Isostearyl isostearate is commonly used in cosmetic sunscreens to improve the even distribution and application of UV filters.
Isostearyl isostearate is included in cosmetic foundations to enhance the blendability and longevity of makeup.
Isostearyl isostearate is found in tinted lip balms, contributing to both color and moisturization.

Isostearyl isostearate is utilized in hair serums to add shine and manageability to the hair.
In hand sanitizers, it can serve as a conditioning agent to counteract the drying effects of alcohol.
Isostearyl isostearate is employed in cosmetic primers for its ability to create a smooth canvas for makeup application.

Isostearyl isostearate is used in cosmetic setting sprays to improve the setting and longevity of makeup.
Isostearyl isostearate is included in cosmetic concealers to enhance the smooth application and coverage of imperfections.
Isostearyl isostearate is utilized in facial cleansers and makeup removers for its gentle cleansing properties.
Isostearyl isostearate is found in cosmetic sheet masks to improve adherence and comfort during use.

Isostearyl isostearate is incorporated into cosmetic stick foundations for easy and convenient application.
Isostearyl isostearate is utilized in cosmetic lip glosses for a glossy finish without a sticky feel.
Isostearyl isostearate is included in cosmetic highlighters for a smooth and radiant application.

Isostearyl isostearate is found in cosmetic blushes and bronzers to enhance the blending and application on the skin.
In cosmetic eye creams, the compound contributes to a silky and moisturizing texture.
Isostearyl isostearate is used in cosmetic setting powders to improve their adherence to the skin.

Isostearyl isostearate is included in cosmetic body scrubs to enhance the spreadability and skin-feel during exfoliation.
Isostearyl isostearate is found in cosmetic body lotions for a luxurious and smooth application on the skin.
Isostearyl isostearate is employed in cosmetic CC creams for color correction and moisturization.
Isostearyl isostearate is included in cosmetic gel formulations for a lightweight and refreshing application.

Isostearyl isostearate is used in cosmetic water-based formulations for its compatibility with aqueous solutions.
Isostearyl isostearate is found in cosmetic fragrance-free products for those with sensitivities.
Isostearyl isostearate is incorporated into cosmetic hair masks for its conditioning and detangling properties.

Isostearyl isostearate is utilized in cosmetic body washes for a rich and moisturizing lather.
Isostearyl isostearate is included in cosmetic body mists for a lightweight and hydrating application.

Isostearyl isostearate plays a crucial role in cosmetic BB creams, contributing to their lightweight texture and coverage.
Isostearyl isostearate is commonly utilized in cosmetic body butters for a rich and nourishing feel on the skin.

Isostearyl isostearate is included in cosmetic gel-based masks for its smooth and cooling application.
Isostearyl isostearate is found in cosmetic primer oils, enhancing the hydration and adherence of makeup.

In cosmetic body scrubs, it aids in providing a soft and exfoliating experience during use.
Isostearyl isostearate is utilized in cosmetic body balms, offering intensive moisturization and a non-greasy finish.
Isostearyl isostearate is included in cosmetic body serums to enhance skin texture and suppleness.
Isostearyl isostearate plays a role in cosmetic dry shampoo formulations, contributing to easy application and absorption.

Isostearyl isostearate is employed in cosmetic cuticle oils for its moisturizing and conditioning properties.
Isostearyl isostearate is found in cosmetic anti-frizz hair products to improve manageability and shine.

Isostearyl isostearate is utilized in cosmetic cleansing balms for a luxurious and effective makeup removal experience.
Isostearyl isostearate is included in cosmetic body powders for a smooth and velvety feel on the skin.
Isostearyl isostearate plays a part in cosmetic body wash oils, providing a gentle and moisturizing cleanse.
Isostearyl isostearate is commonly used in cosmetic hair styling creams for a soft and touchable hold.

In cosmetic depilatory creams, it contributes to a smooth and comfortable hair removal process.
Isostearyl isostearate is found in cosmetic foot creams, offering hydration and relief for dry skin.
Isostearyl isostearate is utilized in cosmetic beard oils for its conditioning and non-greasy properties.
Isostearyl isostearate plays a role in cosmetic body bronzing lotions for an even and radiant application.
Isostearyl isostearate is included in cosmetic hand masks for a rejuvenating and moisturizing effect.

Isostearyl isostearate is commonly used in cosmetic cuticle creams to improve the overall health and appearance of nails.
Isostearyl isostearate is found in cosmetic hair glosses, adding shine and a polished finish to the hair.
Isostearyl isostearate is utilized in cosmetic under-eye creams for a smooth and hydrating application.
In cosmetic massage lotions, it contributes to a glideable and nourishing massage experience.

Isostearyl isostearate is included in cosmetic pre-shave oils for a smooth and comfortable shaving process.
Isostearyl isostearate plays a role in cosmetic fragrance-free products, providing a neutral base for formulations.



DESCRIPTION


Isostearyl isostearate is a chemical compound that belongs to the ester class.
Isostearyl isostearate is commonly used in the cosmetics and personal care industry as an emollient and skin-conditioning agent.
Isostearyl isostearate is derived from isostearyl alcohol and isostearic acid.
Isostearyl isostearate is known for its ability to improve the texture and feel of cosmetic products, providing a smooth and silky finish.

Isostearyl isostearate is a versatile ester widely used in the cosmetics industry.
This compound, derived from isostearyl alcohol and isostearic acid, serves as an effective emollient.
Isostearyl isostearate is known for its skin-conditioning properties, leaving a smooth and silky texture.

As a cosmetic ingredient, it enhances the spreadability and application of various products.
With its emollient nature, it helps improve the overall feel of skincare and haircare formulations.
Isostearyl isostearate acts as a lubricant, contributing to the ease of product application on the skin.

Isostearyl isostearate is particularly valued for its ability to provide a non-greasy, lightweight finish.
In skincare products, it aids in moisturizing and maintaining skin hydration.

Isostearyl isostearate is often included in lip balms and lipsticks for its smoothing effect.
Its compatibility with other cosmetic ingredients makes it a popular choice for formulators.
Isostearyl isostearate contributes to the long-lasting wear of makeup products, such as foundations and powders.

Isostearyl isostearate is well-tolerated by many skin types and is suitable for sensitive skin.
In haircare products, it helps to condition and improve the manageability of hair strands.
Its molecular structure imparts a luxurious and silky feel when incorporated into beauty formulations.
Isostearyl isostearate's moisturizing properties make it beneficial for dry and dehydrated skin conditions.

Isostearyl isostearate enhances the sensory experience of skincare and cosmetic applications.
Its non-comedogenic nature makes it suitable for use in products for individuals prone to acne.
Isostearyl isostearate contributes to the stability and shelf life of cosmetic formulations.

Isostearyl isostearate is often found in creams, lotions, and moisturizers for its skin-loving qualities.
Its film-forming characteristics help create a protective barrier on the skin's surface.

Isostearyl isostearate is transparent and colorless, making it suitable for a wide range of cosmetic products.
Isostearyl isostearate is eco-friendly and biodegradable, aligning with sustainability goals in the industry.
Isostearyl isostearate is odorless, making it ideal for products where fragrance is not desired.

Isostearyl isostearate is synthesized through a controlled process to ensure high purity and quality.
Its compatibility with various active ingredients makes it a versatile component in skincare formulations.



PROPERTIES


Melting Point: 50-55°C
pH: Neutral
Solubility: Insoluble in water
Viscosity: Low
Molecular Weight: 537.0 g/mol
XLogP3-AA: 16.8
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 32
Exact Mass: 536.55323154 g/mol
Monoisotopic Mass: 536.55323154 g/mol
Topological Polar Surface Area: 26.3Ų
Heavy Atom Count: 38
Formal Charge: 0
Complexity: 456
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes



FIRST AID


Inhalation:

If inhaled, move the affected person to fresh air.
Allow for rest and keep the individual comfortable.
Seek medical attention if respiratory irritation persists.


Skin Contact:

In case of skin contact, wash the affected area with plenty of soap and water.
Remove contaminated clothing.
Seek medical attention if irritation, redness, or other symptoms develop.


Eye Contact:

In case of contact with eyes, flush eyes with lukewarm water for at least 15 minutes, lifting upper and lower eyelids.
Seek medical attention if irritation persists.


Ingestion:

If isostearyl isostearate is accidentally ingested, do not induce vomiting.
Rinse the mouth with water.
Seek immediate medical attention or contact a poison control center.


General Advice:

If someone shows signs of irritation or an allergic reaction after exposure to isostearyl isostearate, remove the person from the source of exposure.
Provide comfort and reassurance.
In case of persistent symptoms or if there is uncertainty about the exposure, seek medical advice promptly.



HANDLING AND STORAGE


Handling Conditions:

Personal Protection:
Wear appropriate personal protective equipment (PPE), such as gloves and safety goggles, to prevent skin and eye contact.
Use protective clothing, including long sleeves and pants, to minimize skin exposure.

Ventilation:
Work in a well-ventilated area, or use local exhaust ventilation to control airborne concentrations.

Avoidance of Contact:
Avoid contact with eyes, skin, and clothing.
Do not ingest the substance.

Handling Equipment:
Use suitable handling equipment and tools to minimize direct contact with the chemical.

Hygiene Practices:
Wash hands thoroughly after handling isostearyl isostearate.
Do not eat, drink, or smoke while handling the chemical.

Preventive Measures:
Implement good industrial hygiene practices to minimize the risk of exposure.
Provide eye wash stations and safety showers in areas where the substance is handled.


Storage Conditions:

Storage Location:
Store isostearyl isostearate in a cool, dry, and well-ventilated area.

Temperature Control:
Keep the storage temperature within the specified range provided by the manufacturer.

Container Type:
Use containers made of materials compatible with isostearyl isostearate.
Consult the SDS for guidance.

Protection from Elements:
Protect the substance from direct sunlight and sources of heat.

Separation from Incompatibles:
Store isostearyl isostearate away from incompatible substances.
Check the SDS for information on substances that should be avoided.

Handling of Large Quantities:
If handling large quantities, use appropriate storage facilities with containment measures to prevent spills and leaks.

Labeling:
Ensure that storage containers are clearly labeled with the product name, hazard symbols, and other relevant information.

Security Measures:
Implement appropriate security measures to prevent unauthorized access to the storage area.

Emergency Response:
Have emergency response procedures in place, including spill cleanup measures and contact information for relevant authorities.
ISOSTEARYL ISOSTEARATE
ISOSTEARYL ISOSTEARATE ISOSTEARYL ISOSTEARATE ISOSTEARYL ISOSTEARATE is classified as : Binding Emollient Skin conditioning CAS Number 41669-30-1 EINECS/ELINCS No: 255-485-3 COSING REF No: 34765 Chem/IUPAC Name: Isooctadecyl isooctadecanoate Isostearyl Isostearate Isostearyl Isostearate is a fluid emollient for oils. It provides a rich feel and improves spreading on the skin. It is appropriate for use in lipsticks and as a binding agent for make-up powders. This product does not modify pigment coloration, and provides superfatting properties to compensate for the drying effect of powders Details An emollient ester (oily liquid from Isostearyl Alcohol + Isostearic Acid) that gives excellent slip, lubricity and luxurious softness on skin. It's also popular in makeup products to disperse pigments nicely and evenly. Molecular Weight of Isostearyl Isostearate 537 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) XLogP3-AA of Isostearyl Isostearate 16.8 Computed by XLogP3 3.0 (PubChem release 2019.06.18) Hydrogen Bond Donor Count of Isostearyl Isostearate 0 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Hydrogen Bond Acceptor Count of Isostearyl Isostearate 2 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Rotatable Bond Count of Isostearyl Isostearate 32 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Exact Mass of Isostearyl Isostearate 536.553232 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Monoisotopic Mass of Isostearyl Isostearate 536.553232 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18) Topological Polar Surface Area of Isostearyl Isostearate 26.3 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Heavy Atom Count of Isostearyl Isostearate 38 Computed by PubChem Formal Charge of Isostearyl Isostearate 0 Computed by PubChem Complexity of Isostearyl Isostearate 456 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18) Isotope Atom Count of Isostearyl Isostearate 0 Computed by PubChem Defined Atom Stereocenter Count of Isostearyl Isostearate 0 Computed by PubChem Undefined Atom Stereocenter Count of Isostearyl Isostearate 0 Computed by PubChem Defined Bond Stereocenter Count of Isostearyl Isostearate 0 Computed by PubChem Undefined Bond Stereocenter Count of Isostearyl Isostearate 0 Computed by PubChem Covalently-Bonded Unit Count of Isostearyl Isostearate 1 Computed by PubChem Compound of Isostearyl Isostearate Is Canonicalized Yes The stearate esters (Butyl Stearate, Cetyl Stearate, Isocetyl Stearate, Isopropyl Stearate, Myristyl Stearate, Ethylhexyl Stearate, Isobutyl Stearate) are oily liquids or waxy solids. Ethylhexyl Stearate may also be called Octyl Stearate. In cosmetics and personal care products, stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products. Stearate esters act primarily as lubricants on the skin's surface, which gives the skin a soft and smooth appearance. Butyl Stearate also decreases the thickness of lipsticks, thereby lessening the drag on lips, and imparts water repelling characteristics to nail polishes. Butyl Stearate and Isopropyl Stearate dry to form a thin coating on the skin. Isocetyl Stearate can also be used to dissolve other substances, usually liquids. Function(s) of Isopropyl Stearate: Binder; Skin-Conditioning Agent - Emollient; BINDING; SKIN CONDITIONING Use restrictions of Isopropyl Stearate: Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications Irritation (skin, eyes, or lungs): Human irritant - strong evidence (only for products for use around the eyes, on the skin, or may be aerosolized (airborne)) GHS Hazard Statements of Isopropyl Stearate: Aggregated GHS information from 2 notifications provided by 23 companies to the ECHA C&L Inventory. H413 (100%): May cause long lasting harmful effects to aquatic life Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from all companies. Only Hazard Codes with percentage values above 10% are shown. Molecular Formula: C21H42O2 Molecular Weight: 326.565 g/mol IUPAC Name: propan-2-yl octadecanoate CAS: 112-10-7 EC Number: 203-934-9 Isostearyl Isostearate is a fluid emollient for oils. It provides a rich feel and improves spreading on the skin. It is appropriate for use in lipsticks and as a binding agent for make-up powders. This product does not modify pigment coloration, and provides superfatting properties to compensate for the drying effect of powders. Skincare ingredients: Isostearyl Isostearate What is Isostearyl isostearate? Great for: Emollient like jojoba oil with a virtually non-existent after-feel How it works: It provides a rich but non-greasy skin feel and improves spreading on the skin. It is often used in lipsticks and to bind together make-up powders. Where does isostearyl isostearate come from? Isostearyl isostearate is the ester (the product of an alcohol and an acid) of isosteric alcohol and isostearic acid. Isostearic acid is an isomer of stearic acid, a naturally-occurring fatty acid found in cocoa and shea butter. Isostearic acid and stearic acid have the same chemical formula, but the arrangement of their atoms vary slightly which gives it very different physical properties. For example, stearic acid is solid at room temperature and isostearic acid is clear yellow liquid. Formulation tips Undiluted Isopropyl Isostearate was classified as a slight ocular irritant but otherwise is considered very safe.
ISOSTEARYL LACTATE
SynonymsCMI;MCI;CMIT;IDAS;mci/mi;CMI/MIT;CMIT/MIT;KATHONFP;KATHONLX;Danisol-K CAS No.26172-55-4
ISOTHIAZOLINONE
ISOTHIAZOLINONE = ISOTHIAZOL-3-ONE


CAS Number: 1003-07-2
EC Number: 696-206-9
MDL Number: MFCD09834764
Chemical formula: C3H3NOS


Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO.
Isothiazolinone is a white solid, it is structurally related to isothiazole.
The basic substance of the group of substances, isothiazolinone , is a compound that contains a sulfur in a cyclopentene five-membered ring and a nitrogen atom and a carbonyl group ( thiaazocyclopentenone ).


Isothiazolinones are heterocyclic organic compounds that play an important role in biocides .
Isothiazolinone is a heterocyclic chemical compound related to isothiazole.
Isothiazolinone is an antimicrobial preservative that is often used to control fungi, bacteria, and algae.
Isothiazolinones are heterocyclic compounds that are used as biocides.


Five derivatives are used in significant amounts:
Methylisothiazolinone (MIT, MI)
Chloromethylisothiazolinone (CMIT, CMI, MCI)
Benzisothiazolinone (BIT)
Octylisothiazolinone (OIT, OI)
Dichlorooctylisothiazolinone (DCOIT, DCOI)
There is also butylbenzisothiazolinone (BBIT), which, however, plays a subordinate role.


A Isothiazolinone is derivative as antimicrobial.
Isothiazolinone was tested for inhibition of PCAF activity.
5-Chloroisothiazolinones showed the most potent inhibition of PCAF.
Isothiazolinones (CMIT/MIT) is composed of 5-chloro-2-methyl-4-thiazoline-3-ketone (CMI) and 2-methyl-4-thiazoline-3-ketone (MI).


The importance of Isothiazolinone has been growing over the last few years.
Isothiazolinone is another synthetic chemical widely used in household and personal care as preservatives because of its ability to fight off bacteria and microbes.
Isothiazolinone (Isothiazolinone) is a synthetic substance that is put in cosmetics as a preservative.
Isothiazolinone helps extend life and maintain the condition that is still attractive to be used in cosmetics.


Isothiazolinone is an antimicrobial preservative that is commonly used to control bacteria, fungi, and algae.
Isothiazolinone (sometimes isothiazolone) is an organic compound with the formula (CH)2SN(H)CO.
Isothiazolinone (CAS No. 1003-07-2) is an antimicrobial preservative primarily for water containing solutions, as these are breeding grounds for bacteria, fungi, and algae.


Isothiazolinones are heterocyclic compounds that play an important role in biocides .
Isothiazolinone is a microbicidal agent that is used as an additive to water in the form of a liquid or powder.
Isothiazolinone is classified as reactive and hydrochloric acid, which means it reacts with water to produce chlorine and hydrochloric acid.
The biocidal activity of Isothiazolinone is due to its ability to inhibit the growth of bacteria by reacting with their cell walls and destroying them.


This effect may be due to Isothiazolinone's ability to inhibit cholesterol esterase, an enzyme involved in lipid metabolism that has been shown to be associated with diabetes.
Isothiazolinone is also known for its high values of carbonyl groups and chlorine atoms, making it useful for analytical chemistry experiments using gas chromatography (GC), as well as in agricultural research.



USES and APPLICATIONS of ISOTHIAZOLINONE:
Isothiazolinones find application in the preservation of high pH household and industrial and institutional cleaning formulations, as well as personal care and cosmetic materials.
Isothiazolone itself is of limited interest, but several of its derivatives are widely used preservatives and antimicrobials.
Isothiazolinones are used as preservatives against microorganisms ( bacteria , fungi ) in aqueous dispersions , emulsions and solutions.


Due to their bactericidal and fungicidal effect, they protect, for example, cleaning agents, paints , varnishes and adhesives from microbial decomposition.
Other areas of application for isothiazolinones are in paper manufacture , where they are used to combat slime, and in cooling and process waterand the antimicrobial treatment of textiles; DCOIT and OIT are also used as wood preservatives .
In the past, isothiazolinones were also used very frequently for shower gels, shampoos and cosmetics.


Isothiazolinones are used in cosmetic and as chemical additives for occupational and industrial usage due to their bacteriostatic and fungiostatic activity.
Isothiazolinone is another synthetic chemical widely used in household and personal care as preservatives because of its ability to fight off bacteria and microbes.


Antimicrobial preservatives, Isothiazolinones are synthetic biocides/preservatives.
Isothiazolinones are broad-spectrum, non-oxidizing biocides that can be used in a wide range of industrial applications.
Isothiazolinone formulation helps to inhibit the growth of microbes and has inhibition and biocidal effects on most of the common bacteria, fungi and algae found in water.


Isothiazolinone is most commonly applied in water containing solutions, as these solutions are a breeding ground for bacteria.
There are a number of different products on the market today that use Isothiazolinone like sunscreen, hand sanitizer, shampoo, cosmetics, lotions, and many more.
The purpose of including Isothiazolinone in these products is to inhibit microbial activity that could potentially spoil the product before its expected expiration date.


Isothiazolinone has a high performance, broad spectrum, antimicrobial activity controlling both planktonic and surface growth of bacteria, fungi and algae.
Isothiazolinone has been designed exclusively for water treatment and paper mill application.
Isothiazolinones are used as preservatives against microorganisms (bacteria, fungi) in aqueous dispersions, emulsions and solutions.


Due to their bactericidal and fungicidal effect, they protect, for example, shower gels, shampoos, cosmetics, cleaning agents, paints, varnishes and adhesives from microbial decomposition.
Other areas of application for isothiazolinones are paper production, where they are used to combat slime, cooling and process water , the antimicrobial treatment of textiles and they are also used as wood preservatives .


Isothiazolinones are used as preservatives in cooling lubricants.
Are known here v. a. the octylisothiazolinone, which is mainly added to cooling lubricant concentrates because of its fungicidal (fungicidal) effect, and a mixture of chloromethylisothiazolinone and methylisothiazolinone (usually 3:1), which, due to a lack of stability, only gets into the cooling lubricant through the subsequent addition of separate preservatives.


There are a number of different products on the market today that use Isothiazolinone like sunscreen, hand sanitizer, shampoo, cosmetics, lotions, and many more.
The purpose of including Isothiazolinone in these products is to inhibit microbial activity that could potentially spoil the product before its expected expiration date.


Isothiazolinones are synthetic preservatives used in a range of products including cleaning, laundry and personal care.
Since water-containing solutions are the breeding grounds for bacteria, isothiazolinone can easily be used in such solutions.
Although isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials.


Notably, various products that use isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions.
Isothiazolinones are used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.
Safety InformationThe recommended use of isothiazolinone products by the manufacturers used as wrinkle releaser is not harmful.


The bactericidal effect of Isothiazolinones (CMIT/MIT) is carried out through breaking the bond between bacteria and algae protein.
When contacted with microbes, Isothiazolinones (CMIT/MIT) can quickly inhibit their growth, thus leading to death of these microbes.
Isothiazolinones (CMIT/MIT) has strong inhibition and biocidal effects on ordinary bacteria, fungi and alga, and has many advantages such as high biocidal efficiency, good degradation, no residual, safety in operation, good compatibleness, good stabilization, low cost in operation.


Isothiazolinones (CMIT/MIT) can mix with chlorine and most cation, anion, and non-ionic surfactants.
When used at high dosage, its biosludge stripping effect is excellent.
Isothiazolinones (CMIT/MIT) is a kind of fungicidal with properties of broad spectrum, high efficiency, low toxicity and non-oxidative, it is the ideal biocidal in industrial circulating cool water system and in wastewater treatment in oilfield, papermaking, pesticide, cutting oil, leather, detergent and cosmetics etc..


When Isothiazolinone is used as sludge stripper for grade II, the dosage of 150-300mg/L is preferred, when used as boicide, the dosage of 80-100mg/L is preferred, and charges every 3-7 days.
When Isothiazolinone is used together with quaternary amine, the effect will be better.
When Isothiazolinone is used as industrial fungicide, the dosage of 0.05-0.4% is preferred.


Isothiazolinone is a cost-effective antimicrobial for personal care formulations.
Suggested applications of Isothiazolinone: personal care preservative.
Isothiazolinone is a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems.
Suggested applications of Isothiazolinone: Industrial water treatment. Very low use levels.



MECHANISM OF ACTION OF ISOTHIAZOLINONE:
The antimicrobial activity of isothiazolinones is attributed to their ability to inhibit life-sustaining enzymes, specifically those enzymes with thiols at their active sites.
Isothiazolinone is established that isothiazolinones form mixed disulfides upon treatment with such species.
RSH+isothiazolone

The principal isothiazolones are:
*Methylisothiazolinone (MIT, MI)
*Chloromethylisothiazolinone (CMIT, CMI, MCI)
*Benzisothiazolinone (BIT)
*Octylisothiazolinone (OIT, OI)
*Dichlorooctylisothiazolinone (DCOIT, DCOI)
*Butylbenzisothiazolinone (BBIT)
These compounds all exhibit antimicrobial properties.
They are used to control bacteria, fungi, and algae in cooling water systems, fuel storage tanks, pulp and paper mill water systems, oil extraction systems, wood preservation, and some paints.
They are antifouling agents.
They are frequently used in shampoos and other hair care products.




SYNTHESIS OF ISOTHIAZOLINONE:
Compared to many other simple heterocycles, the discovery of Isothiazolinone is fairly recent, with reports first appearing in the 1960s.
Isothiazolinones can be prepared on an industrial scale by the ring-closure of 3-mercaptopropanamides.
These in turn are produced from acrylic acid via the 3-mercaptopropionic acid:
Ring-closure of the thiol-amide is typically effected by chlorination or oxidation of the 3-sulfanylpropanamide to the corresponding disulfide.
Many other routes have been developed, including addition of thiocyanate to propargyl amides.





BIOLOGICAL SIGNIFICANCE OF ISOTHIAZOLINONE:
In addition to the desired effect of killing or controlling the growth of microorganisms, isothiazolinones also have undesirable effects.
They have high aquatic toxicity and some isothiazolinones (especially CMIT) can cause sensitization in humans through direct contact or airborne exposure and some isothiazolinones (especially CMIT) can cause skin.




PHYSICAL and CHEMICAL PROPERTIES of ISOTHIAZOLINONE:
Chemical formula: C3H3NOS
Molar mass: 101.127
Appearance: white solid
Melting point: 74–75 °C (165–167 °F; 347–348 K)
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point
Melting point/range: 74 - 75 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available


Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available
Density: No data available
Relative density: No data available
Relative vapor density: No data available


Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Melting point: 74-75 °C
Density: 1.366±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Solid
pka: 9.12±0.20(Predicted)
color: Off-White



FIRST AID MEASURES of ISOTHIAZOLINONE:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOTHIAZOLINONE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ISOTHIAZOLINONE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOTHIAZOLINONE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ISOTHIAZOLINONE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ISOTHIAZOLINONE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available



SYNONYMS:
1,2-Thiazol-3(2H)-one
Isothiazolin-3-one
3(2H)-Isothiazolone, isothiazolin
Isothiazalone
thiazol-3-one
3-isothiazolone
Isothiazol-3-one
1,2-thiazol-3-one
Isothiazolin-3-one
3(2H)-Isothiazolone
Isothiazol-3(2H)-one
Isothiazol-3(2H)-one 97%
3-Oxo-2,3-dihydroisothiazole
thiazol-3-one
3-isothiazolone
Isothiazol-3-one
1,2-thiazol-3-one
3(2H)-Isothiazolone
3-isothiazolone
Isothiazol-3-one
1,2-thiazol-3-one
3(2H)-Isothiazolone
isothiazol-3(2H)-one


ISOTHIAZOLINONES
Isothiazolinones exhibit antimicrobial properties.
Isothiazolinones are antifouling agents.


CAS Number: 26172-55-4, 2682-20-4, 1003-07-2
EC Number: 247-500-7
MDL Number: MFCD09834764
Chemical formula: C3H3NOS



SYNONYMS:
CMIT, Isothiazolinones, CMIT, Isothiazolinone, CMI, CMIT/MIT, 5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE, MCI, 5-Chloro-2-methyl-3(2H)-isothiazolone, Chloromethylisothiazolinone, 5-chloro-2-methyl-2H-isothiazol-3-one, isothiazolin, 1,2-Thiazol-3(2H)-one, Isothiazolin-3-one, 3(2H)-Isothiazolone, isothiazolin, Isothiazalone, thiazol-3-one, 3-isothiazolone, Isothiazol-3-one, 1,2-thiazol-3-one, Isothiazolin-3-one, 3(2H)-Isothiazolone, Isothiazol-3(2H)-one, Isothiazol-3(2H)-one 97%, 3-Oxo-2,3-dihydroisothiazole, thiazol-3-one, 3-isothiazolone, Isothiazol-3-one, 1,2-thiazol-3-one, 3(2H)-Isothiazolone, 3-isothiazolone, Isothiazol-3-one, 1,2-thiazol-3-one, 3(2H)-Isothiazolone, isothiazol-3(2H)-one, 1,2-Thiazol-3(2H)-one, Isothiazolin-3-one, 3(2H)-Isothiazolone, isothiazolin



Isothiazolinones are a preservative used in cosmetic products such as shampoos and hair care products.
Isothiazolinones are permitted in Europe for all cosmetic applications, but at a maximum concentration of 15 ppm.
Therefore, the support of a laboratory competent in the analysis of preservatives in cosmetics is essential to be able to perform the analysis of

Isothiazolinones (/ˌaɪsoʊˌθaɪ.əˈzoʊlɪnoʊn/; sometimes isothiazolone) are an organic compound with the formula (CH)2SN(H)CO.
A white solid, Isothiazolinones are structurally related to isothiazole. Isothiazolinones are of limited interest, but several of their derivatives are widely used preservatives and antimicrobials.


Isothiazolinones exhibit antimicrobial properties.
Isothiazolinones are antifouling agents.
Isothiazolinones are frequently used in shampoos and other hair care products.


Isothiazolinones are synthetic preservatives used in a range of products including cleaning, laundry and personal care.
Isothiazolinones are known as sensitizersiv, which have been linked to allergic contact dermatitis.
Isothiazolinones, some reminders about these compounds:


Isothiazolinones are a family of biocides based on a heterocycle: 1,2-thiazol-3-one.
It is a thiazole with a ketone function or a lactam with a sulphur atom in the unsaturated ring.
The biocidal effect of Isothiazolinones is achieved in two stages: from the very first minutes, cell growth is inhibited and irreversible damage is caused within a few hours.


Isothiazolinones react with proteins and interfere with oxygen consumption, respiration, ATP synthesis and energy production.
Isothiazolinones do, however, have some undesirable effects including high aquatic toxicity and skin sensitization which can cause allergic dermatitis mainly on the hands and face.


The presence of Isothiazolinones in cosmetic products is authorised in Europe at a maximum level of 15 ppm.
Indeed, due to their high polarity, some Isothiazolinones are difficult to isolate from water.
Isothiazolinones are a heterocyclic chemical compound related to isothiazole.


Isothiazolinones an antimicrobial preservative that is often used to control fungi, bacteria, and algae.
Since water-containing solutions are the breeding grounds for bacteria, Isothiazolinones can easily be used in such solutions.
Isothiazolinones are a cost-effective antimicrobial for personal care formulations.


Suggested applications of Isothiazolinones: personal care preservative.
Isothiazolinones are composed of 5-chloro-2-methyl-4-thiazoline-3-ketone (CMI) and 2-methyl-4- thiazoline-3-ketone(MI). Isothiazolinones’ bactericidal effect is carried out by breaking the bond between bacteria and algae protein.


When contacted with microbes, Isothiazolinones can quickly inhibit their growth.
Thus leading to the death of these microbes.
Isothiazolinones also have certain effects on silt’s peeling, dispersing, and infiltration.


As a result, Isothiazolinones can protect the water quality and ensure the normal operation of the equipment.
The performance of Isothiazolinones is very stable.
And the applicability is strong.


Just put a small number of Isothiazolinones in the area that water treatment is needed.
Based on the excellent characteristics of bactericidal algaecide, Isothiazolinones are quickly recognized by various industries.
For example, Isothiazolinones are widely used in industrial circulating cooling water systems, such as chemical, textile, power plants, industrial storage tanks, cooling towers, swimming pools, fountain landscape water, and other industrial projects.


Isothiazolinones are an antimicrobial preservative primarily for water containing solutions, as these are breeding grounds for bacteria, fungi, and algae.
There are a number of different products on the market today that use Isothiazolinones like sunscreen, hand sanitizer, shampoo, cosmetics, lotions, and many more.


The purpose of including Isothiazolinones in these products is to inhibit microbial activity that could potentially spoil the product before its expected expiration date.
Isothiazolinones can also disinfect and kill the common bacterium, fungus and water plant.


For better effect, Isothiazolinones can be used in conjunction with the ionic and non-ionic water treatment chemicals.
After usage, Isothiazolinones are easy to be degraded into non-toxic molecule without secondary pollution.
Isothiazolinones are a kind of non-oxidizing bactericide with broad-spectrum, high efficiency and low toxicity.


Isothiazolinones's active content is isothiazolinone and its derivative mixture.
Isothiazolinones have strong penetration ability for the cell membrane of microorganism and can decompose and destroy the cell tissue.
Isothiazolinones, with the chemical formula C3H3NOS and CAS registry number 26172-55-4, is a compound known for its antimicrobial properties.


Isothiazolinones are effective against a wide range of microorganisms and have a low toxicity profile, making it a popular choice for preservation.
Overall, Isothiazolinones play a crucial role in maintaining the quality and longevity of many everyday products.



USES and APPLICATIONS of ISOTHIAZOLINONES:
A white solid, Isothiazolinones are structurally related to isothiazole. Isothiazolinones are of limited interest, but several of their derivatives are widely used preservatives and antimicrobials.
Isothiazolinones are used to control bacteria, fungi, and algae in cooling water systems, fuel storage tanks, pulp and paper mill water systems, oil extraction systems, wood preservation, and some paints.


Isothiazolinones are used especially as an antifouling agent, i.e. paint for ship hulls to prevent the formation of barnacles, etc.
Isothiazolinones are preservatives used against algae, fungi and bacteria in cooling systems, fuel tanks, paper mills, wood preservation or oil extraction.
Isothiazolinones are also used in lacquers, paints or varnishes.


Isothiazolinones are also used in the surface treatment of mould on historical monuments (such as the Lascaux cave or the Angkor temples in Cambodia).
As a preservative, Isothiazolinones are also used in cosmetic products such as shampoo or hair care products, detergents and laundry detergents.
Isothiazolinones are commonly used as a preservative in various industrial and consumer products, such as paints, adhesives, and personal care products.


Isothiazolinones work by inhibiting the growth of bacteria, fungi, and algae, helping to prevent the degradation and spoilage of these products.
Isothiazolinones are a high performance industrial microbiocide for use in recirculating water cooling towers, wood, mold and mildew control, pulp and paper mills, air washer systems.


Although Isothiazolinones have no direct applications, their derivatives such as 5-chloro-2-methyl-4-isothiazolin-3-on and 2-methyl-4-isothiazolin-3 which are used together as preservatives in commercial households and cosmetics products, for instance, cleaners, shampoos, and washing materials.
Notably, various products that use Isothiazolinones are in the market, including shampoo, hand sanitizer, and lotions.


Isothiazolinones is used in these products as an inhibitor of microbial activity that could lead to the product spoiling before the expected expiration date.
The recommended use of Isothiazolinones products by the manufacturers used as wrinkle releaser is not harmful.


Determination of Isothiazolinones in consumer goods:
Isothiazolinones are common preservatives (biocides) in cosmetics, chemical formulations, and printing inks.
Used as preservatives, biocides and disinfectants in a variety of industrial and domestic applications.


When used as a sludge stripper for grade II, 150~300 mg/L is preferred.
When used as a biocide, 80~100 mg/l is preferred.
And charges every 3~7 days.


The Isothiazolinones can’t be used together with oxidative fungicides like chlorine.
And Isothiazolinones can’t be used in cooling water systems containing sulfur.
When Isothiazolinones are used together with a quaternary amine, the effect will be better.


When Isothiazolinones is used as an industrial fungicide, 0.05~0.4% is preferred.
Isothiazolinones have a high performance, broad spectrum, antimicrobial activity controlling both planktonic and surface growth of bacteria, fungi and algae.


Isothiazolinones have been designed exclusively for water treatment and paper mill application.
Isothiazolinones are antimicrobials used to control bacteria, fungi, and algae in cooling water systems, fuel storage tanks, pulp and paper mill water systems, oil extraction systems, wood preservation and antifouling agents.


Isothiazolinones are frequently used in personal care products such as shampoos and other hair care products, as well as certain paint formulations.
Isothiazolinones are antimicrobials used to control bacteria, fungi, and algae in cooling water systems, fuel storage tanks, pulp and paper mill water systems, oil extraction systems, wood preservation and antifouling agents.


Isothiazolinones are frequently used in personal care products such as shampoos and other hair care products, as well as certain paint formulations.
There, often combinations of MIT and CMIT (known as Kathon CG) or MIT and BIT are used.


-Isothiazolinones are heterocyclic compounds that are used as biocides.
Five derivatives are used in significant amounts:
*Methylisothiazolinone (MIT, MI)
*Chloromethylisothiazolinone (CMIT, CMI, MCI)
*Benzisothiazolinone (BIT)
*Octylisothiazolinone (OIT, OI)
*Dichlorooctylisothiazolinone (DCOIT, DCOI)
The derivative butylbenzisothiazolinone (BBIT) also exists, but does not have the same importance.



FUNCTIONS OF ISOTHIAZOLINONES:
Isothiazolinones can be widely used as bactericide for industrial circulating cool water, oilfield water and the like in the industries such as oil refining, chemical industry, fertilizer, electric power and metallurgy to control the growth of microorganism effectively.



PROPERTIES OF ISOTHIAZOLINONES:
Isothiazolinones have strong inhibition and biocidal effects on ordinary bacteria, fungi, and alga.
And Isothiazolinones have many advantages, such as high biocidal efficiency, good degradation, no residual, safety in operation, good compatibleness, good stabilization, and low cost in operation.

Isothiazolinones can mix with chlorine and most cation, anion, and non-ionic surfactants.
However, Isothiazolinones's bio-sludge stripping effect is excellent when used at high dosages.
Isothiazolinones are fungicidal with broad spectrum properties, high efficiency, low toxicity, and non-oxidative.
Isothiazolinones are the ideal biocidal in the industrial circulating cool water system.

Also, in wastewater treatment, the oilfield, papermaking, pesticide, cutting oil, leather, detergent, cosmetics, etc.
Isothiazolinones have a high inhibitory effect on various fungi and algae, such as green algae, brown algae, fungi, and bacteria.
At the same time, Isothiazolinones also control the growth of slime in water.



KEY FEATURES AND BENEFITS OF ISOTHIAZOLINONES:
*Rapid Inhibition of Microbial Growth
*Effective at low concentrations
*Requires lesser dosing
*Well effective over a wide pH range
*Non foaming
*Biodegradable



THERE ARE FIVE IMPORTANT DERIVATIVES IN THE FAMILY OF ANTIMICROBIAL ISOTHIAZOLINONES:
*Methylisothiazolinone (MIT, MI);
*Chloromethylisothiazolinone (CMIT, MIT, MCI);
*Benzisothiazolinone (BIT);
*Octylisothiazolinone (ILO, RO);
*Dichlorooctylisothiazolinone (DCOIT, COD).



ANALYSIS OF ISOTHIAZOLINONES IN YOUR COSMETIC PRODUCTS:
You need to analyse Isothiazolinones in your cosmetic products.
First of all, Isothiazolinones are a family of biocides composed from a heterocycle, 1,2-thiazol-3-one.
Isothiazolinones are used against bacteria and fungi in lacquers, paints, antifoulings and varnishes.

Isothiazolinones' biocidal effect comes from a two-step mechanism: a rapid inhibition of growth and respiration, followed by irreversible damage to the cell within hours.
By reacting with the cell’s proteins, oxygen consumption, hence respiration, and ATP synthesis, hence energy production, are inhibited.



THE PRINCIPAL ISOTHIAZOLINONES ARE:
*Methylisothiazolinone (MIT, MI)
*Chloromethylisothiazolinone (CMIT, CMI, MCI)
*Benzisothiazolinone (BIT)
*Octylisothiazolinone (OIT, OI)
*Dichlorooctylisothiazolinone (DCOIT, DCOI)
*Butylbenzisothiazolinone (BBIT)



MECHANISM OF ACTION OF ISOTHIAZOLINONES:
The antimicrobial activity of Isothiazolinones is attributed to their ability to inhibit life-sustaining enzymes, specifically those enzymes with thiols at their active sites.
Isothiazolinones are established that Isothiazolinones form mixed disulfides upon treatment with such species.



SYNTHESIS OF ISOTHIAZOLINONES:
Compared to many other simple heterocycles, the discovery of Isothiazolinones are fairly recent, with reports first appearing in the 1960s.
Isothiazolinones can be prepared on an industrial scale by the ring-closure of 3-mercaptopropanamides.
These in turn are produced from acrylic acid via the 3-mercaptopropionic acid



PHYSICAL and CHEMICAL PROPERTIES of ISOTHIAZOLINONES:
Chemical formula: C3H3NOS
Molar mass: 101.127
Appearance: white solid
Melting point: 74–75 °C (165–167 °F; 347–348 K)
Physical state: solid
Color: No data available
Odor: No data available
Melting point/freezing point
Melting point/range: 74 - 75 °C
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available

Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient:
n-octanol/water: No data available
Vapor pressure: No data available

Density: No data available
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Melting point: 74-75 °C
Density: 1.366±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
form: Solid
pka: 9.12±0.20(Predicted)

color: Off-White
CBNumber:CB4132565
Molecular Formula:C4H4ClNOS
Molecular Weight:149.6
MDL Number:MFCD00792550
MOL File:26172-55-4.mol
Melting point: 42-45?C
Boiling point: 109.7°C
Density 1.25 (14% aq.)
Properties:
Refractive index: n20/D 1.378
Storage temp.: Refrigerator
Solubility: Chloroform (Slightly), DMSO (Slightly),
Methanol (Slightly, Heated)
pKa: -4.06±0.40 (Predicted)

Form: Liquid
Stability: Stable, Incompatible with strong oxidizing agents
LogP: 0.240 (est)
Identifiers:
Indirect Additives used in Food Contact Substances:
5-CHLORO-2-METHYL-4-ISOTHIAZOLIN-3-ONE
CAS DataBase Reference: 26172-55-4 (CAS DataBase Reference)
FDA UNII: DEL7T5QRPN
NIST Chemistry Reference: 5-Chloro-2-methyl-3(2h)-isothiazolone (26172-55-4)
EPA Substance Registry System: 5-Chloro-2-methyl-4-isothiazolin-3-one (26172-55-4)
Chemical Properties:
Chemical formula: C3H3NOS
Molar mass: 101.127 g/mol
Appearance: White solid
Melting point: 74–75 °C (165–167 °F; 347–348 K)



FIRST AID MEASURES of ISOTHIAZOLINONES:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ISOTHIAZOLINONES:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ISOTHIAZOLINONES:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ISOTHIAZOLINONES:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses.
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ISOTHIAZOLINONES:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ISOTHIAZOLINONES:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
no information available


ISOTRIDECANOL ( Isotridecyl alcohol )
Isotridecanol

Isotridecyl alcohol= isotridecanol= isotridecan-1-ol= 11-methyldodecanol

Isotridecanol is a clear, high-boiling, oily liquid with a faint, characteristic odour.
Isotridecanol is miscible with most common organic solvents, but is practically insoluble in water.

Isotridecanol is a branched, linear and primary alcohol with high mole wt. Isotridecanol is a used as a raw material in the industries of cosmetics, drug delivery, metal processing, fiber finish, thermostable and biodegradable lubricant and solvent as well as surfactant.

Isotridecyl Alcohol is used in some Hair Care products as it softens and smoothens the hair and enhances its appearance.
Commonly Isotridecyl Alcohol is used amongst others as an intermediate in production of surfactants and softeners as a raw material in the industries of cosmetics, drug delivery, metal processing, fiber finish, thermostable and biodegradable lubricant and solvent as well as surfactant.
Isotridecyl Alcohol can also be found as fragrance ingredient in personal care products.


Isotridecanol is starting material for the production of plasticizers, lubricants, and auxiliaries in the chemical and allied industries.Isotridecanol is Low-volatility solvent for oils, waxes, fats and dyes.
Isotridecanol is used as defoamer in the textile, paper and coating industries.

Isotridecanol (ITDA) is an organic-chemical compound from the group of alcohols.
Under normal conditions, isotridecanol is a colorless, weakly smelling liquid that is insoluble in water.

The highly pure C13 alcohol is an important intermediate product in the production of surface-active substances, so-called surfactants.
The term iso refers to the methyl group on the penultimate carbon atom and on the end opposite the OH group Branched C12 carbon chain.
The correct systematic name is therefore 11-methyl-1-dodecanol.

Isotridecanol is regarded as a real petrochemical specialty and is launched as a particularly high-quality product with an almost 100% content of C13 alcohols.


Isotrideconal is used, among other things, as an intermediate in the manufacture of surfactants and plasticizers.
Isotrideconal is often used in high-quality industrial applications, e.g. in the production of cleaning agents and lubricants.
Another application of Isotrideconal is in the form of special esters in high-quality lacquers and lacquer resins.
In addition, isotridecanol may also be used in the EU as a fragrance in cosmetic articles and preparations using the INCI name of the same name.

Isotrideconal has a general purpose as a dispersant and emulsifier with good wetting properties.


Chemical Structure: Mixture of C13H27OH Isomer
Chemical Name: ISOTRIDECANOL
Molecular Formula: C13H28O
Molecular Weight: 200.4
CAS No.: 27458-92-0
EINECS No.: 248-469-2
CAS: 27458-92-0;68526-86-3
Molecular Formula: C13H28O






Synonyms:
alcohols, C11-14-iso-, C13-rich
C11-14-iso-alcohols, C13-rich
1-dodecanol, 11-methyl-
11-methyl-1-dodecanol
11-methyldodecan-1-ol
11-methyldodecanol
isotridecan-1-ol
isotridecyl alcohol



Application of Isotridecanol:
Cleaning and furnishing care products
Fabric, textile, and leather products not covered elsewhere
Ink, toner, and colorant products
Lubricants and greases
Mining


All other basic organic chemical manufacturing
All other chemical product and preparation manufacturing
Mining (except oil and gas) and support activities
Paint and coating manufacturing
Petroleum lubricating oil and grease manufacturing
Plastic material and resin manufacturing
Plastics product manufacturing
Printing ink manufacturing
Rubber product manufacturing
Soap, cleaning compound, and toilet preparation manufacturing
Synthetic rubber manufacturing
Textiles, apparel, and leather manufacturing

Isotridecanol
C11-14-iso-Alcohols, C13-rich
11-Methyl-1-dodecanol
11-Methyl-1-dodecanol [German]
11-Méthyl-1-dodécanol [French]
11-Methyldodecan-1-ol
11-methyldodecanol
1-Dodecanol, 11-methyl-
27458-92-0 [RN]
288-581-9 [EINECS]
68526-86-3 [RN]
Alcohol C-13 Oxo
Isotridecyl alcohol
[27458-92-0]
11-Methyldodecanol-d7
158923-11-6 [RN]
1794766-65-6 [RN]
Alcohols, C11-14-iso-, C13-rich
FIXATEUR ITC
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:77438
Isotridecan-1-ol
Isotridecanol-
Isotridecylalcohol
ISO-TRIDECYL-ALCOHOL




Isotridecanol
11-Methyldodecanol
ISOTRIDECYL ALCOHOL
11-methyldodecan-1-ol
85763-57-1
Isotridecan-1-ol
27458-92-0
68526-86-3
Iso-Tridecyl-alcohol
Alcohols, C11-14-iso-, C13-rich
Isotridecanol-
11-Methyl-1-dodecanol
UNII-VX3T72M5SG
1-Dodecanol, 11-methyl-
VX3T72M5SG
EINECS 248-469-2
EINECS 271-235-6
EINECS 288-581-9
Alcohol C-13 Oxo




Final product applications
Agricultural chemicals
Detergents and cleaners
Lubricants
Metal working and fuel additives
Additives
Oil and gas
Paints
Inks
Coatings
Adhesives
Plastic and rubber additives
Specialty
Industrial applications
Textile
Leather processing


Exxal® 13 (Isotridecyl Alcohol)
Substance
11-Methyldodecan-1-ol
CAS
68526-86-3
EC number
271-235-6
REACH compliant
Yes
Purity
99%
Color
Colorless
Appearance
Liquid


Product Description
Exxal alcohols are isomeric branched, primary alcohols that contain both even- and odd-numbered hydrocarbon chains, ranging from C8 to C13.

In general, there are two main types of structures in industrial alcohols:

Linear (or straight-chain) molecules: obtained from synthetic or natural sources
Branched chain alcohols: produced from propylene and butene

Our customers use Exxal alcohols to synthesize derivatives used in industrial applications:

Surfactants – industrial applications, cleaning, and oil and gas

Polymer additives – stabilizers, antioxidants and flame retardants
Adhesives – acrylates

Lube and fuel additives
Lubricant esters

They are also used as solvents or cosolvents for coatings, inks and metal extraction in mining.

Benefits

High-purity Exxal alcohols exhibit reactivity typical of higher primary alcohols. Thanks to their branched structure, Exxal alcohols offer many performance advantages to ethoxylates compared to linear alcohol-based ones:

Low pour point – prohibits gel and wax formation, facilitates processing of alcohols and derivatives
Biodegradability – all of our alcohols and their ethoxylates meet the OECD 301F readily biodegradable threshold for isomeric mixtures
Superior wetting power of derived surfactants – excellent candidates for resource extraction and nonylphenol substitution
Powerful solvency in coatings and inks, fully soluble in hydrocarbon fluids while enhancing their solvency power
Wide viscosity ranges in synlubes
Industries
Leather & Textiles , Paints & Coatings , Additive Manufacturing
Product Groups
Emulsifiers & Dispersing Agents , Binders & Resins , Antioxidants & Stabilizers , Additives
Substance details




ISOTRIDECYL ALCOHOL 30 EO 70 %
Composition: Isotridecyl polyethylene glycol ether with 30-mole ethylene oxide


ISOTRIDECYL ALCOHOL 30 EO 70 %: Aqueous solution of a fatty alcohol polyglycol ether.

CAS number: 9043-30-5


Synonyms: C 13 Alcohol 30 Ethoxylate, 70 % in Water, Fatty alcohol polyglycol ether, Isotridecyl polyethylene glycol ether with 30-mole ethylene oxide, C 13 Alcohol 30 EO,



ISOTRIDECYL ALCOHOL 30 EO 70% is a nonionic emulsifier for emulsion polymerization.


Use of ISOTRIDECYL ALCOHOL 30 EO 70 %:

The use of ISOTRIDECYL ALCOHOL 30 EO 70% in emulsion polymerization of vinyl acetate, acrylate, and acrylate/styrene dispersions reduces coagulation and improves electrolyte resistance and freeze/thaw stability.

ISOTRIDECYL ALCOHOL 30 EO 70 % is added to the emulsion before, during, or after the polymerization process.

ISOTRIDECYL ALCOHOL 30 EO 70 % improves latex stability and prevents coagulation during polymerization.

Improving the latex properties means better electrolyte, shear stability, and freeze-thaw stability.



Use of the substance/preparation:

Industry sector: Industrial Performance Chemicals
Type of use: Emulsifier for emulsion polymerization

Product properties *)
Active substance content
about 70 % with 30% water


Item: Specification

Consistency at 20°C: liquid (visual)

Transparency at 20°C: clear (visual)

Hazen colour: max. 130 EN 1557

pH value 5% as is in water: 6.0 - 8.0 DIN EN 1262

Water content: 29.0 - 31.0 % DIN 51777

Viscosity (dynamic): approx. 2.300 mPa.s (20 °C) Brookfield

Viscosity at 50°C: 100 - 200 mPas ISO 6388

Pourpoint: approx. 5 °C DIN/ISO 3016


Appearance
at 5°C: white paste
at 25°C: clear, colorless liquid
at 50°C: clear, colorless liquid
pH value (DIN EN 1262), 5 % as is in water: 6 - 8


Solubility at 25 °C: clear soluble in water

Density at 25 °C: approx. 1.08 g/cm³

Viscosity at 25 °C (Brookfield, Spindle LV1): about 700 mPas

Flashpoint (DIN/ISO 2592): > 100 °C

Critical Micelle Concentration: 0,88 g/l active material in water

Surface Activity at 1 g/l active substance: about 38 mN/m

HLB value: about 17

Biodegradability: 57 % (28 d)

Method: OECD 301 B

Fish toxicity : LC50 > 100 mg/l (96 h, zebrafish)

Method: OECD 203

Bacteria toxicity : EC50 > 5 mg/l (Vibrio fisheri)

Method: DIN EN ISO 11348-2

Dissolved Organic carbon(DOC) : 1.919 mg/g
Method: DIN/EN 1484

Chemical oxygen demand (COD): 632 mg/g
Method: ISO/DIS 15705



Isotridecyl Alcohol 30 EO 70 % is used in the Emulsion polymerization of styrene, acrylic acid copolymers, and vinyl acetate copolymers.

Isotridecyl Alcohol 30 EO 70 % is liquid and readily miscible, and it has substantial wetting and emulsifying properties.

Isotridecyl Alcohol 30 EO 70 enables higher dispersion, freeze-thaw, and electrolyte stability.



Application of Polymers, where ISOTRIDECYL ALCOHOL 30 EO 70 % is used:

1. Paints and coatings applications
– Architectural coatings (paints)
– Industrial coatings
– Wood coatings

2. Paper application
– Paper sizing
– Pulp binder

3. Adhesives

4. Carpet back sizing application

5. Textile application

6. Caulk and sealants, cement concrete application

7. Others



Handling and Storage
Below 15°C ISOTRIDECYL ALCOHOL 30 EO 70% starts crystallization after heating
up at 30°C ISOTRIDECYL ALCOHOL 30 EO 70% turns into a clear liquid again.





This information is based on our present knowledge and is intended to provide general notes on our products and their uses.
It should not, therefore, be construed as guaranteeing specific properties of the products described on their suitability for a particular application.
Any existing industrial property rights must be observed.
The quality of our products is guaranteed under our General Conditions of Sale.

*) These characteristics are for guidance only and should not be considered product specifications.
The tolerances are given in the product specification sheet.
For further information on product properties, toxicological, ecological, and safety data, please refer to the safety data sheet.



OTHER PRODUCTS OF ATAMAN CHEMICALS THAT MIGHT BE OF INTEREST:

ISOTRIDECYL ALCOHOL 40 EO 70 %
C13 Alcohol 40 EO 70 %
NP 40
Nonyl Phenol 40 Ethoxylate


ISOTRIDECYL ALCOHOL 50 EO 60 %
C13 Alcohol 50 EO 60 %
NP 50
Nonyl Phenol 50 Ethoxylate


Please check www.atamankimya.com for more products.









ISOTRIDECYL ISONONANOATE
ISOTRIDECYL LAURATE, N° CAS : 94134-83-5, Nom INCI : ISOTRIDECYL LAURATE, Nom chimique : 11-Methyldodecyl Dodecanoate. N° EINECS/ELINCS : 302-853-7: Ses fonctions (INCI), Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance, Agent d'entretien de la peau : Maintient la peau en bon état
ISOTRIDECYL LAURATE
ISOTRIDECYL SALICYLATE, N° CAS : 1863871-63-9, Nom INCI : ISOTRIDECYL SALICYLATE. Nom chimique : Benzoic acid, 2-hydroxy, reaction products with isotridecanol. Ses fonctions (INCI), Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface. Agent d'entretien de la peau : Maintient la peau en bon état
ISOTRIDECYL SALICYLATE
ITACONIC ACID; Methylenesuccinic acid; Methylene Butanedioic acid; Propylenedicarboxylic acid; 2-Propene-1,2-dicarboxylic acid; cas no: 97-65-4
ISOTRIDECYL STEARATE

Isotridecyl Stearate is a pharmaceutical-grade intermediate that is required during the organic synthesis procedure. Its molecular weight is 466.82 and its purity level is 99.0%. The boiling point of this chemical is 489.8 degrees C at 760 mm Hg. Its relative density is 0.857g/cm3. It is accessible in colourless or pale yellow transparent liquid form. Isotridecyl Stearate has 255.5 degrees C flashpoint. The Standard of this substance has been verified on the basis of its shelf life, composition, chemical attributes, possible toxin content and processing method. Importance is also given on checking its chemical stability when used under different temperature.


CAS NO : 31565-37-4
EC NO : 250-703-3
IUPAC NAMES: 
11-methyldodecyl octadecanoate


SYNONYMS
Isotridecyl stearate;Octadecanoic acid, isotridecyl ester;31565-37-4;11-methyldodecyl octadecanoate;UNII-J8793TKA30;J8793TKA30;Stearic acid, isotridecyl ester;EINECS 250-703-3;SCHEMBL2699239;Isotridecyl Stearate, veg. based; 11-methyldodecyl ester;ZINC95803367;W-110802;Q27281337;11-methyldodecyl octadecanoate
;11-methyldodecyl stearate;octadecanoic acid isotridecyl ester;octadecanoic acid, 11-methyldodecyl ester;octaearic acid;isotridecyl ester; isotridecyl ester;Isotridecylstearat;isotridecyl stearate;isotridecyl ester;Octadecanoic acid, isotridecyl ester;Isotridecylstearate; Octadecanoicacid,isotridecylester; Stearicacid,isotridecylester; 11-methyldodecylstearate; 11-methyldodecyloctadecanoate; 31565-37-4;11-methyldodecyl octadecanoate 31565-37-4 CTK4G7366 EINECS 250-703-3 Exceparl TD-S Isotridecyl stearate Isotridecyl Stearate; veg. based ISOTRIDECYL STEARATE;isotridecyl stearateIsotridecyl octadecanoate; J8793TKA30 LS-166598 NS00019608 Octadecanoic acid; isotridecyl ester Octadecanoic acid;isotridecyl ester Q27281337 SCHEMBL2699239;11-methyldodecyl ester;isotridecyl ester Stearicacid;isotridecyl ester (7CI,8CI) UNII-J8793TKA30 W-110802 ZINC95803367


Isotridecyl stearate is the raw material for spin finishes and oiling agent for textile, rubber processing agent, Plastic lubricant, Paint, Ink additive.
Isotridecyl stearate is a clear, colourless oily liquid that works as a medium feel emollient.
Isotridecyl stearate absorbs very quickly into the skin, leaves no shine and gives a nice, velvety after-feel.
Isotridecyl stearate is used in cosmetics as a thickening agent and emollient.
Isotridecyl stearate is a lubricity additive, provides a substantially lubricious film
Isotridecyl stearate has good metal adhesion properties
Isotridecyl stearate has good corrosion protection properties
* Characterised by a viscosity of 16C at 40 C
* Characterised by a pour point of 7 C


Isotridecyl stearate is used in Neat oils, Soluble oils, Semi-Synthetics, Vanishing oils
Isotridecyl stearate is used in cosmetics for skin conditioning/moisturizing.

Industry Uses
-Finishing agents
-Lubricants and lubricant additives
Consumer Uses
-Lubricants and greases
-Metal products not covered elsewhere


Industry Processing Sectors
-Fabricated metal product manufacturing
-Textiles, apparel, and leather manufacturing

The stearate esters (Butyl Stearate, Cetyl Stearate, Isocetyl Stearate, Isopropyl Stearate, Myristyl Stearate, Ethylhexyl Stearate, Isobutyl Stearate) are oily liquids or waxy solids.
Ethylhexyl Stearate may also be called Octyl Stearate. In cosmetics and personal care products, stearate esters are used most frequently in the formulation of eye makeup, skin makeup, lipstick and skin care products.
Why is it used in cosmetics and personal care products?
Stearate esters act primarily as lubricants on the skin's surface, which gives the skin a soft and smooth appearance.
Butyl Stearate also decreases the thickness of lipsticks, thereby lessening the drag on lips, and imparts water-repelling characteristics to nail polishes.
Butyl Stearate and Isopropyl Stearate dry to form a thin coating on the skin. Isocetyl Stearate can also be used to dissolve other substances, usually liquids.

Scientific Facts:
The stearate esters are prepared by reacting stearic acid with the appropriate alcohol (butyl, cetyl, isobutyl, isocetyl, isopropyl, myristyl or ethylhexyl alcohol).
Stearate esters have the unique properties of low viscosity and oily nature, which results in a nongreasy, hydrophobic film when applied to the skin or lips.
Stearic acid is found in animal and vegetable fats.

Function in the product
Affects the application properties of cosmetics - gives a good glide when spreading (e.g. lipsticks on the lips), reduces sticking and greasiness of the cosmetic. Stick plasticizer - gives the sticks elasticity, prevents them from crushing.

Cosmetic action
Used in skin and hair care preparations, it creates an occlusive layer on the surface, which prevents excessive evaporation of water from the surface (indirect moisturizing effect), thus conditioning, i.e. softening and smoothing the skin and hair.

Isotridecyl Stearate
cas no 31565-37-4 Octadecanoic acid, isotridecyl ester; Stearic acid, isotridecyl ester; Isotridecyl Stearate, veg. based; Octadecanoic acid,isotridecyl ester;
Isovaleric acid
SYNONYMS Isopropylacetic acid; Delphinic acid; Isopropylacetic acid; 3-Methylbutyric acid; 3-Methylbutanoic acid; beta-Methyl butyric acid; Isobutylformic acid; Isopentanoic acid; Iso C-5 Acid; Isovalerianic; 3-Methylbutyrate; Kyselina isovalerova; CAS NO. 503-74-2
ITACONIC ACID
Itaconic Acid Itaconic acid, or methylidenesuccinic acid, is an organic compound. This dicarboxylic acid is a white solid that is soluble in water, ethanol, and acetone. Historically, itaconic acid was obtained by the distillation of citric acid, but currently it is produced by fermentation. The name itaconic acid was devised as an anagram of aconitic acid, another derivative of citric acid. Production Since the 1960s, it is produced industrially by the fermentation of carbohydrates such as glucose or molasses using fungi such as Aspergillus itaconicus or Aspergillus terreus. For A. terreus the itaconate pathway is mostly elucidated. The generally accepted route for itaconate is via glycolysis, tricarboxylic acid cycle, and a decarboxylation of cis-aconitate to itaconate via cis-aconitate-decarboxylase. The smut fungus Ustilago maydis uses an alternative route. Cis-aconitate is converted to the thermodynamically favoured trans-aconitate via aconitate-Δ-isomerase (Adi1). trans-Aconitate is further decarboxylated to itaconate by trans-aconitate-decarboxylase (Tad1). Itaconic acid is also produced in cells of macrophage lineage. It was shown that itaconate is a covalent inhibitor of the enzyme isocitrate lyase in vitro. As such, itaconate may possess antibacterial activities against bacteria expressing isocitrate lyase (such as Salmonella enterica and Mycobacterium tuberculosis). However, cells of macrophage lineage have to "pay the price" for making itaconate, and they lose the ability to perform mitochondrial substrate-level phosphorylation. Laboratory synthesis Dry distillation of citric acid affords itaconic anhydride, which undergoes hydrolysis to itaconic acid. Reactions Upon heating, itaconic anhydride isomerizes to citraconic acid anhydride, which can be hydrolyzed to citraconic acid (2-methylmaleic acid). Steps in conversion of citric acid to citraconic acid via itaconic and aconitic acids. Partial hydrogenation of itaconic acid over Raney nickel affords 2-methylsuccinic acid. Itaconic acid is primarily used as a co-monomer in the production of acrylonitrile butadiene styrene and acrylate latexes with applications in the paper and architectural coating industry. Properties and Application of Itaconic Acid Itaconic acid is a white crystalline powder having a hygroscopic property and a specific odor. Its melting point is 167–168 °C and the boiling point is 268 °C. Water solubility is 83.1 g l−1, and a solution (80 mg l−1) of itaconic acid in pure water has a pH of 2.0. The density of itaconic acid is 1.63 (20 °C). The pKa values of itaconic acid, its two dissociation steps, are 3.84 and 5.55 (25 °C). The equilibrium constants are K1 = 1.4 × 10−4 and K2 = 3.6 × 10−6 (25 °C). Itaconic acid is mainly used in the plastic and paint industry. It is an unsaturated dicarbonic acid, and can readily be incorporated into polymers and used at a concentration of 1–5% (w/w) as a comonomer in polymers. The polymerized methyl, ethyl, or vinyl esters of itaconic acid are used as plastics, adhesives elastomers, and coatings. Styrene butadiene copolymers containing itaconic acid yield rubber-like resins of excellent strength and flexibility and water-proofing coatings with good electrical insulation. Other fields for use are synthetic fibers, lattices, detergents, and cleaners. On the other hand, several mono- and diesters of partially substituted itaconic acid possess anti-inflammatory or analgesic activities, and a special new market has opened for the use of itaconic acid pharmaceutical fields. A small quantity of itaconic acid is used as acidulant. Itaconic acid (2-methylenesuccinic acid, 1-propene-2–3-dicarboxylic acid) is an unsaturated, weak dicarboxylic acid (pKa =3.83 and 5.41), discovered in 1837 as a thermal decomposition product of citric acid. The presence of the conjugated double bond of the methylene group allows polymerization both by addition and condensation. Esterification of the two carboxylic groups with different co-monomers is also possible (Kuenz et al., 2012). These diverse properties have led to a variety of applications in the pharmaceutical, architectural, paper, paint, and medical industries such as plastics, resins, paints, synthetic fibers, plasticizers, and detergents. Recently, itaconic acid applications have penetrated the dental, ophthalmic and drug delivery fields (Hajian and Yusoff, 2015). Itaconic acid polymers could even replace the petroleum-based polyacrylic acid, which has a multi-billion dollar market (Saha et al., 2019). Not surprisingly, the US Department of Energy assigned itaconic acid as one of the top 12 most promising building block chemicals for bio-based economy in 2004 (Werpy and Petersen, 2004). Little is known about the reasons why fungi produce itaconate. Like the other organic acids, as outlined above, also itaconic acid might serve as acidifier of the environment and thus provide selective advantage for the acid-tolerant A. terreus over other micro-organisms. However, itaconic acid also has clear inhibitory properties: in macrophages of mammals, bacterial infection prompts the induction of a gene encoding a cis-aconitate decarboxylase, resulting in itaconic acid formation that inhibits bacterial metabolism as part of the immune response. The effect has been attributed to the inhibition of succinate dehydrogenase and isocitrate lyase (McFadden et al., 1971), the latter being a key enzyme of the glyoxylate cycle, required for the survival of pathogens inside a host. In turn, a few strains of these bacteria have evolved to be capable of degrading itaconate (Sasikaran et al., 2014). Itaconic acid also induces a transcription factor which is essential for protection against oxidative and xenobiotic stresses, and to attenuate inflammation (Kobayashi et al., 2013; Bambouskova et al., 2018). Whether a similar function of itaconate exists in the fungi producing it has not yet been studied. The biosynthetic pathway of itaconic acid resembles that of citric acid, the latter acid being a direct precursor of the former. The only difference is that citric acid in A. terreus is further metabolized via cis-aconitate to itaconate by cis-aconitate decarboxylase (Bonnarme et al., 1995). To this end, cis-aconitate is transported out of the mitochondria by a specific antiporter in exchange for oxaloacetate (Li et al., 2011a,b). Itaconic acid – formed upon cis-aconitate decarboxylation – is finally secreted out of mycelia by a specific cell membrane transporter. Genes encoding these three enzymes, and a fourth one encoding a transcription factor, constitute the “itaconate gene cluster” in the A. terreus genome, while the cluster is notably absent in A. niger. Although several itaconate producers have been tested, the plant pathogenic Basidiomycete Ustilago maydis (the corn smut fungus) – and particularly its low pH-stable relative Ustilago cynodontis (Hosseinpour Tehrani et al., 2019b) – seems to be the only one with a reasonable chance to become another industrial platform organism (Hosseinpour Tehrani et al., 2019a). Ustilago has developed an alternative biochemical pathway to synthetize itaconate inasmuch as cis-aconitate is converted to the thermodynamically favored trans-aconitate by aconitate-delta-isomerase. Trans-aconitate is then decarboxylated to itaconate by trans-aconitate-decarboxylase. Production of Itaconic Acid by Fermentation Processes Itaconic acid is produced in batch fermentation in a process largely similar to that of citric acid. The carbon source should be in an easily metabolizable form (glucose syroup, molasses, and crude starch hydrolysates) and diluted to approximately 10% wt. Phosphate limitation is necessary for growth restriction. Some trace metals should also be in limited amounts and this is usually achieved by treating the media with hexacyanoferratl or addition of copper. The pH is kept between 2.8 and 3.2. Lower pH values favor the formation of byproducts. Yields of 50–60% of the theoretical yield are obtained in 8–10 days [5]. For many years, there seems to be almost no research interest for the production of itaconic acid and the process remained unchanged since its introduction. The situation is different today. Itaconic acid is listed by the US Department of Energy (DOE) as one of the 12 building blocks with the highest potential to be produced by industrial biotechnology [11]. Its current low production limits its uses. Metabolic engineering strategies, as an approach for yield improvement, have not yet been applied with A. terreus, as they were restricted by the poor knowledge of the genetics of itaconic acid biosynthesis. Recently, however, three genes – crucial in itaconic acid production by A. terreus – were identified by researchers in Toegepast Natuurwetenschappelijk Onderzoek (TNO), the Netherlands [15]. Apart from the new knowledge on the genetics of biosynthesis, the development of new fermentation technologies and more sophisticated bioprocess control has led to renewed interest in improving itaconic acid production. Novel fed-batch strategies and continuous processes using immobilized cultures are being developed and investigated. Itaconic acid is a dicarboxylic acid, which is used in industry as a precursor of polymers used in plastics, adhesives, and coatings. New uses of itaconic acid-derived polymers are under active investigation. The production of itaconic acid for 2001 was quoted as 15 000 tons. There is a renewed interest in this chemical as industry searches for substitutes of petroleum-derived chemicals. Virtually all itaconic acid produced is by fermentation by specific strains of A. terreus. Itaconic acid production is a further perversion of the Krebs cycle, citrate is converted as normally into cis-aconitate, which for reasons unknown is, in some organisms, decarboxylated into itaconitate, which has no known metabolic role in the cell. The fact that different strains of Aspergillus and more generally of fungi can divert metabolic pathways to the overproduction and secretion of useful chemicals, coupled with the fact that these organisms can grow on residues of processes such as sugar and ethanol production, open the possibility of engineering pathways to produce high value chemicals through ‘green’, low polluting, waste-eliminating procedures. Production Itaconic Acid Itaconic acid is an example of a di-carbonic unsaturated acid. These acids are used as building blocks for large numbers of compounds, such as resins, paints, plastics, and synthetic fibers (acrylic plastic, super absorbants, and antiscaling agents) [67]. The CAC intermediate cis-aconitate is enzymatically processed by cis-aconitate dehycarboxylase (CadA) to produce itaconic acid [68]. At the industrial scale the most explored organism for the fermentative production of itaconic acid is Aspergillus terrus. The biosynthetic pathway of itaconic acid is like citrate biosynthesis, where the flux of the CAC is used in the catalytic conversion of cis-aconitate into itaconic acid. Thus citrate is synthesized from oxaloacetate and acetyl CoA, while oxaloacetate is synthesized from pyruvate by anaplerosis, which starts from the pyruvate that is the end product of glycolysis (Fig. 13.17). Itaconic acid (methylenesuccinic acid, C5H6O4) (Figure 17) is a white colorless crystalline, hygroscopic powder soluble in water, ethanol, and acetone. It is an unsaturated diprotic acid, which derives its unique chemical properties from the conjugation of one of its two carboxylic acid groups with its methylene group. Itaconic acid was discovered by Baup in 1837 as a product of pyrolytic distillation of citric acid. The name itaconic was devised as an anagram of aconitic. Itaconic acid is formed in fermentation of some sugars. In 1929, Kinoshita first showed the acid to be a metabolic product of Aspergillus itaconicus. A derivative of itaconic acid (trans-phenylitaconic acid) was isolated from another natural source (Artemisia argyi). The biosynthetic pathway of itaconic acid from glucose is similar to that of citric acid, which occurs via the glycolytic pathway and anaplerotic formation of oxaloacetate by CO2 fixation and via the TCA cycle (Figure 2). Itaconic acid is formed by the cytosolic enzyme aconitate decarboxylase from cis-aconitic acid. Another biosynthetic pathway from pyruvate through citramalic acid, citraconic acid, and itartaric acid also results in itaconic acid (Figure 18). In contrast to several other organic acids (e.g., citric, isocitric, lactic, fumaric, and l-malic acid) itaconic acid is used exclusively in nonfood applications, especially in the polymer industry. Itaconic acid derivatives are used in medicine, cosmetics, lubricants, thickeners, and herbicides (e.g., substituted itaconic acid anilides). Itaconic acid is produced solely by batch submerged fungal fermentation. Aspergillus terreus has been used from the 1940s in the fermentation process, which is similar to that of citric acid (see ‘Citric acid’), that is, it requires an excess of readily metabolizable sugar (glucose syrup, crude starch hydrolysates, and decationized molasses – up to 200 g l−1 sugar), continuous aeration, a low initial pH (between 3 and 5), sufficient nitrogen, high magnesium sulfate concentration (0.5%), low phosphate to limit biomass production, and a limitation in metal ions (zinc, copper, and iron). However, there exists one significant difference in that the sensitivity of this fungus to the formed acid, in contrast to A. niger, necessitates maintaining of the pH at 2.8–3.1 throughout the fermentation, in order to obtain high amounts of the acid. At present, the published production yield of itaconic acid is about 85% of theoretical, accompanied by product concentrations of about 80 g l−1 during a cultivation at 39–42 °C for 8–10 days. Recovery of itaconic acid is accomplished by first separating the fungal biomass by filtration followed by evaporation, treatment with active carbon, and crystallization and recrystallization. Actual markets for itaconic acid are currently limited because the fungal fermentation is carried out at a relatively high cost. New biotechnological approaches, such as published immobilization techniques, screening programs for other producing organisms (such as yeast), and genetic engineering of A. terreus (the annotated genome sequence of A terreus strain NIH 2624 has been publicly released), or of A. niger, could lead to higher production of itaconic acid. Also, the use of alternative substrates may reduce costs and thus open the market for new and expanded applications of this acid. This valuable acid can be produced by several organisms, such as Candida sp., Pseudozyma antarctica, and several species of Aspergillus [49], but the two most common microorganisms used are Aspergillus terreus, used in industrial processes, and Ustilago maydis, which is currently being actively investigated as a possible industrial product. The acid is used commercially as a comonomer in some synthetic rubbers (styrene-butadiene and nitrilic) and as a plasticizer in the formulation of other polymers. Its production is traditionally done using sugars as raw materials, in a technology that was developed in the first half of the 20th century [50], but that was not developed due to the low competitivity of the acid with the petrochemical acrylic acid. With the development of integrated and sustainable processes, the interest in the bioproduction of itaconic acid is renewed. Itaconic acid, or methylidenesuccinic acid, is an organic compound. This dicarboxylic acid is a white solid that is soluble in water, ethanol, and acetone. Historically, itaconic acid was obtained by the distillation of citric acid, but currently it is produced by fermentation. The name itaconic acid was devised as an anagram of aconitic acid, another derivative of citric acid. Production Since the 1960s, it is produced industrially by the fermentation of carbohydrates such as glucose or molasses using fungi such as Aspergillus itaconicus or Aspergillus terreus. For A. terreus the itaconate pathway is mostly elucidated. The generally accepted route for itaconate is via glycolysis, tricarboxylic acid cycle, and a decarboxylation of cis-aconitate to itaconate via cis-aconitate-decarboxylase. The smut fungus Ustilago maydis uses an alternative route. Cis-aconitate is converted to the thermodynamically favoured trans-aconitate via aconitate-Δ-isomerase (Adi1). trans-Aconitate is further decarboxylated to itaconate by trans-aconitate-decarboxylase (Tad1). Itaconic acid is also produced in cells of macrophage lineage. It was shown that itaconate is a covalent inhibitor of the enzyme isocitrate lyase in vitro. As such, itaconate may possess antibacterial activities against bacteria expressing isocitrate lyase (such as Salmonella enterica and Mycobacterium tuberculosis). However, cells of macrophage lineage have to "pay the price" for making itaconate, and they lose the ability to perform mitochondrial substrate-level phosphorylation. Dry distillation of citric acid affords itaconic anhydride, which undergoes hydrolysis to itaconic acid. Reactions Upon heating, itaconic anhydride isomerizes to citraconic acid anhydride, which can be hydrolyzed to citraconic acid (2-methylmaleic acid). Steps in conversion of citric acid to citraconic acid via itaconic and aconitic acids. Partial hydrogenation of itaconic acid over Raney nickel affords 2-methylsuccinic acid. Itaconic acid is primarily used as a co-monomer in the production of acrylonitrile butadiene styrene and acrylate latexes with applications in the paper and architectural coating industry. Itaconic acid is produced using A. terreus, from simple sugars. The production can be done using submerged solid fermentation, and the typical substrates are derived from sugar production, such as molasses. The accepted mechanism for itaconic acid production consists of the conversion of cis-aconitate to itaconate by an enzymatically catalyzed decarboxylation [53] (Fig. 18.6). Cis-aconitate is part of the Krebs cycle, so that the process is aerobic—actually extremely oxygen dependent, as determined by Gyamerah [54]. Calcium and zinc are important [55], as well as copper [56], and the maintenance of a low phosphate level is essential [53]. The ideal temperature is 40°C, and pH must be reduced to 2 to start the production. The process is extremely aerobic for the first 72 h of the process, with yields around 60%w/w (product/substrate) [55]. The final concentration ranges between 30 and 60 g/L depending on the substrate [56–58]. After fermentation, the broth is clarified and the free acid can be concentrated and crystallized, but if a base is used for partial neutralization during the process (which can increase the yield), it is necessary to remove the cations used in the crystallization. The production of itaconic acid in SSF is still elusive: reports describe productions on the order of 5–40 g/kg dry substrate [59]. Some of the reports that describe higher yields, around 60%, actually use a support soaked with a nutritive solution [60,61]. A comparison between synthetic liquid and solid media showed that the process in SSF has a lower conversion (16%–23%) than that of the submerged process (around 60%). There is no definite explanation for the lower production in solid-state yet, but there seems to be an excess of phosphate or the lack of essential nutrients in most solid substrates tested for itaconic acid reduction. First obtained from the distillation of citric acid, since 1960 itaconic acid has been produced by fermentation of carbohydrates by A. terreus (Mitsuyasu et al., 2009; Hajian and Yusoff, 2015). Itaconic acid has been applied in a numerous range of industries with the larger producers in the world being the USA, Japan, Russia, and China (Global Industry Analysts Inc., 2011). During the 1950s, itaconic acid was used in industrial adhesives. In that period, itaconic acid was used at an industrial scale and large amounts of it were required. It has been employed as a detergent and in shampoos, as well as in plastics, elastomers, fiberglass, and in the coating process of carpets and book covers (Mitsuyasu et al., 2009; Jin et al., 2010). Besides that itaconic acid may also be used as artificial gems and synthetic glasses (Kin et al., 1998). Lately, the applications of the compound have reached the biomedical fields, such as the ophthalmic, dental and drug delivery fields (Hajian and Yusoff, 2015). Several studies have focused on improving and optimizing the production of itaconic acid from A. terreus in recent years. The biotechnological aspects involved in the metabolic pathways of itaconic acid and the production process parameters have been reviewed by Klement and Büchs (2013). Regarding the production, Amina et al. (2013) obtained itaconic acid using oil byproduct jatropha curcas seed cake, while Li et al. (2011), Huang et al. (2014), and van der Straat et al. (2014) studied the itaconic acid production by using genetic engineering techniques. In this process the relevant pathways have been revealed and new microbial production platforms designed, contributing to an enhanced production of itaconic acid. Furthermore, the reduction of its production costs is an important aspect for itaconic acid producers, either by optimizing processes or by using cost-favorable raw materials. Itaconic acid or methylene succinic acid is a high-value platform chemical that finds application in polymer industry, wastewater treatment, and ion-exchange chromatography sector (Willke and Vorlop, 2001). It can be converted to 3-methyltetrahydrofuran that has superior emission and combustion properties when compared to gasoline. Industrial production of itaconic acid is carried out with A. terreus using glucose as the sole carbon source. Itaconic acid production by metabolically engineered Neurospora crassa using lignocellulosic biomass was evaluated by Zhao et al. (2018). Cis-aconitic acid decarboxylase gene was heterologously expressed in N. crassa to synthesize itaconic acid. The engineered strain was capable of producing itaconic acid (20.41 mg/L) directly from lignocellulosic biomass. Itaconic acid production from biomass hydrolyzate using Aspergillus strains was reported by Jiménez-Quero et al. (2016). Acid and enzymatic hydrolyzates were evaluated for the production of itaconic acid. Maximum itaconic acid production (0.14%) was observed when submerged fermentation was carried out with corncob hydrolyzate by A. oryzae. The study reveals the possibility of SSF of biomass for the production of itaconic acid. Klement et al. (2012) evaluated itaconic acid production by Ustilago maydis from hemicellulosic fraction of pretreated beech wood. One of the advantages of U. maydis is that the strain grows as yeast-like single cells, and it can survive under high osmotic stress. The study revealed that under mild pretreatment conditions, U. maydis would be a promising candidate for itaconic acid production. Fine tuning of pretreatment conditions should be carried out for the improved production of itaconic acid. Production Itaconic Acid Itaconic acid is an example of a di-carbonic unsaturated acid. These acids are used as building blocks for large numbers of compounds, such as resins, paints, plastics, and synthetic fibers (acrylic plastic, super absorbants, and antiscaling agents) [67]. The CAC intermediate cis-aconitate is enzymatically processed by cis-aconitate dehycarboxylase (CadA) to produce itaconic acid [68]. At the industrial scale the most explored organism for the fermentative production of itaconic acid is Aspergillus terrus. The biosynthetic pathway of itaconic acid is like citrate biosynthesis, where the flux of the CAC is used in the catalytic conversion of cis-aconitate into itaconic acid. Thus citrate is synthesized from oxaloacetate and acetyl CoA, while oxaloacetate is synthesized from pyruvate by anaplerosis, which starts from the pyruvate that is the end product of glycolysis (Fig. 13.17) [69]. Itaconic acid (IA) can be used: • As a comonomer in the polymerization of polyacrylonitrile (PAN) to promote the thermo-oxidative stabilization of polymer.[1] • In combination with acrylamide to form (poly[acrylamide-co-(itaconicacid)]) to synthesize biodegradable superabsorbent polymers.[2] • To synthesize biobased polyester composite in fabric industry. Itaconic acid is an unsaturated dicarbonic acid which has a high potential as a biochemical building block, because it can be used as a monomer for the production of a plethora of products including resins, plastics, paints, and synthetic fibers. Some Aspergillus species, like A. itaconicus and A. terreus, show the ability to synthesize this organic acid and A. terreus can secrete significant amounts to the media (>80 g/L). However, compared with the citric acid production process (titers >200 g/L) the achieved titers are still low and the overall process is expensive because purified substrates are required for optimal productivity. Itaconate is formed by the enzymatic activity of a cis-aconitate decarboxylase (CadA) encoded by the cadA gene in A. terreus. Cloning of the cadA gene into the citric acid producing fungus A. niger showed that it is possible to produce itaconic acid also in a different host organism. This review will describe the current status and recent advances in the understanding of the molecular processes leading to the biotechnological production of itaconic acid. Itaconic acid (2-methylidenebutanedioic acid) is an unsaturated di-carbonic acid. It has a broad application spectrum in the industrial production of resins and is used as a building block for acrylic plastics, acrylate latexes, super-absorbents, and anti-scaling agents (Willke and Vorlop, 2001; Okabe et al., 2009). Since the 1960s the production of itaconic acid is achieved by the fermentation with Aspergillus terreus on sugar containing media (Willke and Vorlop, 2001). Although also other microorganisms like Ustilago zeae (Haskins et al., 1955), U. maydis, Candida sp. (Tabuchi et al., 1981), and Rhodotorula sp. (Kawamura et al., 1981) were found to produce itaconic acid, A. terreus is still the dominant production host, because so far only bred strains of this species can reach levels of up to 80–86 g/L (Okabe et al., 2009; Kuenz et al., 2012). Since the 1990s, itaconic acid as a renewable material is attracting a lot of interest. Currently, the worldwide production capacity of itaconic acid is expected to be about 50 kt per year, facing a demand of about 30 kt (Shaw, 2013, Itaconix Corporation, personal communication). Especially, for the production of polymers it is of interest, because in the future it can function as a substitute for acrylic and methacrylic acid used for the production of plastics (Okabe et al., 2009). However, these applications require an even lower price of the starting material. The current knowledge about the biotechnological production of itaconic acid was recently reviewed (Willke and Vorlop, 2001; Okabe et al., 2009). The latter review covers the industrial production of itaconic acid and the applications of this product. Therefore, we focus in this report on the recent advances with an emphasis on the biochemistry of the process and new genetic engineering targets. For rational strain improvement, it is essential to understand the underlying biological concepts and biochemical pathways leading to the production of this important organic acid in microorganisms. Biosynthesis Pathway Kinoshita (1932) recognized that a filamentous fungus was able to produce itaconic acid and consequently described this species as A. itaconicus. The biosynthesis of itaconic acid was for a long time hotly debated, because it was not clear whether itaconic acid arises from a pathway including parts of the tricarboxylic acid (TCA) cycle or an alternative pathway via citramalate or the condensation of acetyl-CoA. Bentley and Thiessen (1957a) proposed a pathway for the biosynthesis of itaconic acid, which is depicted in Figure 1. Starting from a sugar substrate like glucose the carbon molecules are processed via glycolysis to pyruvate. Then the pathway is split and part of the carbon is metabolized to Acetyl-CoA releasing a carbon dioxide molecule. The other part is converted to oxaloacetate so that the previously released carbon dioxide molecule is again incorporated. In the first steps of the citric acid cycle, citrate and cis-aconitate are formed. In the last step, the only itaconic acid pathway dedicated step, cis-aconitate decarboxylase (CadA) forms itaconic acid releasing carbon dioxide. This pathway was confirmed by tracer experiments with 14C and 13C labeled substrates (Bentley and Thiessen, 1957a; Winskill, 1983; Bonnarme et al., 1995) and also the necessary enzymatic activities have been all determined (Jaklitsch et al., 1991). The formation of carboxylic acids, like citric and itaconic acid, involves the shuttling of intermediate metabolites between different intracellular compartments and utilizes the different enzymatic capabilities of the respective compartment. In case of itaconic acid the compartmentalization of the pathway was analyzed by fractionized cell extracts distinguishing the enzymatic activity of a mitochondrial from a cytosolic enzyme. It was found that the key enzyme of the pathway, CadA, is not located in the mitochondria but in the cytosol (Jaklitsch et al., 1991), whereas the enzymes preceding in the pathway, namely citrate synthase and aconitase, are found in the mitochondria. However, a residual level of aconitase and citrate synthase activity is also found in the cytosolic fraction. The proposed mechanism is that cis-aconitate is transported via the malate–citrate antiporter into the cytosol (Jaklitsch et al., 1991). However, so far it was not shown whether cis-aconitate makes use of the mitochondrial malate–citrate antiporter or uses another mitochondrial carrier protein to be translocated to the cytosol. Besides A. terreus, itaconic acid is known to be produced also by other fungi like U. zeae (Haskins et al., 1955), U. maydis (Haskins et al., 1955; Klement et al., 2012), Candida sp. (Tabuchi et al., 1981), and Rhodotorula sp. (Kawamura et al., 1981). No further investigations exist about the underlying reaction principles leading to itaconic acid formation in those species. However, recent evidence (Strelko et al., 2011; Voll et al., 2012) points into the direction that CadA activity constitutes the general pathway toward the formation of itaconic acid in nature. Very recently, itaconic acid was detected in mammalian cells, where it was found in macrophage-derived cells (Strelko et al., 2011). Those cells also possess a CadA activity and have the ability to form itaconic acid de novo. But, up to now no specific gene encoding this enzymatic activity was identified in mammalian cells. However, the physiological role of itaconic acid in mammalian cells is still unknown. Strelko et al. (2011) speculate on the role of itaconic acid as an inhibitor of metabolic pathways, because it is described as an enzymatic inhibitor. On the one hand, itaconic acid is known to inhibit isocitrate lyase (Williams et al., 1971; McFadden and Purohit, 1977), which is the crucial part of the glyoxylate shunt, and thus can act as an antibacterial agent. On the other hand, itaconic acid can inhibit fructose-6-phosphate 2-kinase (Sakai et al., 2004) and thus have a direct influence on the central carbon metabolism. In rats it was shown that a itaconate diet leads to a reduced visceral fat accumulation, because of a suppressed glycolytic flux (Sakai et al., 2004). Itaconic Acid Pathway Specific Enzymes and Genes The reaction catalyzed by the cis-aconitic acid decarboxylase was already described in 1957 (Bentley and Thiessen, 1957a,b). Subsequently performed 13C and 14C labeling experiments (Winskill, 1983; Bonnarme et al., 1995) confirmed the reaction scheme depicted in Figure 2. Itaconic acid is formed by an allylic rearrangement and decarboxylation from cis-aconitic acid removing either carbon C1 or C5 from the starting citric acid molecule (because of the symmetry of the molecule). Catabolization of Itaconic Acid Much is known about the biosynthesis of itaconic acid and the underlying enzymatic mechanisms, but for a complete biochemical picture of a certain metabolite, also the knowledge about its degradation is necessary. Unfortunately, the information about the degradation pathway of itaconic acid is sc
ITACONIC ACID
A product of the fermentationof the flamentous fungus Aspergillus niger.
Itaconic acid is usedcommercially in the production ofadhesives and paints.
Itaconic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.

CAS: 97-65-4
MF: C5H6O4
MW: 130.1
EINECS: 202-599-6

Itaconic acid, or methylidenesuccinic acid, is an organic compound.
Itaconic acid is a white solid that is soluble in water, ethanol, and acetone.
Historically, Itaconic acid was obtained by the distillation of citric acid, but currently it is produced by fermentation.
The name Itaconic acid was devised as an anagram of aconitic acid, another derivative of citric acid.

Itaconic acid is an unsaturated binary organic acid.
Chemical properties are more active, easy to polymerize, and can also be copolymerized with other monomers, such as acrylic, succinic acid, and styrene.
Soluble in water, ethanol and acetone, slightly soluble in chloroform, benzene and ether.
Itaconic acid has a special smell and can sublimate under vacuum.
Itaconic acid can also be copolymerized with other monomers.
Itaconic acid is not easy to volatilize and can be decomposed by overheating.

Itaconic acid Chemical Properties
Melting point: 165-168 °C (lit.)
Boiling point: 268°C
Density: 1.573 g/mL at 25 °C (lit.)
Vapor pressure: 0.0000115 Pa (20 °C)
Refractive index: 1.4980 (estimate)
Fp: 268°C
Storage temp.: Store below +30°C.
Solubility: 77.49g/l
Form: Crystalline Powder or Crystals
pka: 3.85(at 25℃)
Specific Gravity: 1.573
Color: White to light beige
PH: 3.5(1 mM solution);2.95(10 mM solution);2.43(100 mM solution);
Water Solubility: Soluble in water, acetone, methanol, hexane and ethanol.
Slightly soluble in benzene, chloroform, carbon disulfide and petroleum ether.
Sensitive: Hygroscopic
Merck: 14,5242
BRN: 1759501
Stability: Light Sensitive
InChIKey: LVHBHZANLOWSRM-UHFFFAOYSA-N
LogP: -0.301 at 20℃
CAS DataBase Reference: 97-65-4(CAS DataBase Reference)
NIST Chemistry Reference: Itaconic acid (97-65-4)
EPA Substance Registry System: Itaconic acid (97-65-4)

Uses
Itaconic acid is used in the preparation of acrylonitrile-butadiene-styrene and acrylate latexes.
Itaconic acid is also used to prepare poly-itaconic acid, resins biofuel components and ionomer cements.
Itaconic acid finds application in the textile, chemical and pharmaceutical industries.
Itaconic acid is also used as an additive in fibers and ion exchange resins to increase abrasion, waterproofing, physical resistance, dying affinity and better duration.
Further, Itaconic acid acts as a co-monomer used in the preparation of acrylic fibers and rubbers, reinforced glass fiber, artificial diamonds and lens.
In addition to this, Itaconic acid acts as a binder and sizing agent in non-weaving fibers.
The major uses for Itaconic acid are in copolymerizations, resins, plasticizers, and as lube oil additives.

1. Itaconic acid and its polymer add a small amount of natural substances can be made into efficient deodorant, with ammonia, amine alkaline odor and hydrogen sulfide and other acidic odor reaction, can also be made with deodorant function of paper, plastic film and other products.

2. Itaconic acid and styrene and butadiene copolymerization can be made into S.B.R latex, can be used for paper coating, so that the paper is strong and strong and the printing pattern is bright; Used for metal, concrete coating, easy to color and not affected by natural conditions; For paint additives can improve the quality of paint; For carpet sizing can make the synthetic fiber carpet durable.

3. Itaconic acid and acrylic acid or methacrylic acid or its ester polymerization resin, can be used for surface coating and emulsion paint.
As a leather coating can increase the plasticity of leather; Used for automobile, electrical appliances, cold storage coatings with strong adhesion, color and appearance and resistance to adverse weather and other advantages; Used as electrophoretic coating with excellent adhesion; the addition of polyvalent metal oxide can be made into a dental adhesive with good extrusion performance, strong adhesion and good physiological adaptability.
The addition of chloroalkyl dimethyl benzyl ammonium chloride can be made into a water-soluble coating for food packaging materials, bacterial contamination of the packaging surface can be reduced.

4. Itaconic acid esters can be used in paint, weak acid ion exchange resin, lubricating oil additives, binders and plasticizers, powder pressure plastic and sealant.

5. Itaconic acid to form other derivatives can be used as pharmaceuticals, cosmetics reagents, lubricants, thickeners, herbicides and improve the performance of silk and wool fabrics.

6. Itaconic acid is a raw material for the production of citraconic acid, mesaconic acid, itaconic anhydride, etc.

Itaconic acid used as comonomer of polyacrylonitrile fiber, can also be used in the preparation of plasticizers, lubricant additives, etc.
Preparation of synthetic fiber, an important monomer of synthetic resin and plastic, ion exchange resin; Can also be used as a carpet mounting agent, paper coating agent, binder, paint dispersion latex.
Ester Derivatives of Itaconic acid can be used for Copolymerization of styrene and the like or plasticizers of polyvinyl chloride.

Production
Since the 1960s, Itaconic acid is produced industrially by the fermentation of carbohydrates such as glucose or molasses using fungi such as Aspergillus itaconicus or Aspergillus terreus.

For A. terreus the Itaconic acid pathway is mostly elucidated.
The generally accepted route for Itaconic acid is via glycolysis, tricarboxylic acid cycle, and a decarboxylation of cis-aconitate to itaconate via cis-aconitate-decarboxylase.

The smut fungus Ustilago maydis uses an alternative route.
Cis-aconitate is converted to the thermodynamically favoured trans-aconitate via aconitate-Δ-isomerase (Adi1).
trans-Aconitate is further decarboxylated to itaconate by trans-aconitate-decarboxylase.

Itaconic acid is also produced in cells of macrophage lineage.
Itaconic acid was shown that itaconate is a covalent inhibitor of the enzyme isocitrate lyase in vitro.
As such, itaconate may possess antibacterial activities against bacteria expressing isocitrate lyase (such as Salmonella enterica and Mycobacterium tuberculosis).

However, cells of macrophage lineage have to "pay the price" for making itaconate, and they lose the ability to perform mitochondrial substrate-level phosphorylation.

Laboratory synthesis
Dry distillation of citric acid affords itaconic anhydride, which undergoes hydrolysis to itaconic acid.

Synonyms
Itaconic acid
97-65-4
2-Methylenesuccinic acid
METHYLENESUCCINIC ACID
2-methylidenebutanedioic acid
Methylenebutanedioic acid
Propylenedicarboxylic acid
Butanedioic acid, methylene-
itaconate
2-Propene-1,2-dicarboxylic acid
Succinic acid, methylene-
2-methylenebutanedioic acid
MFCD00004260
AI3-16901
25119-64-6
2-Methylene-Succinic Acid
CHEMBL359159
butanedioic acid, 2-methylene-
DTXSID2026608
CHEBI:30838
NSC3357
NSC-3357
Q4516562YH
DTXCID006608
CAS-97-65-4
HSDB 5308
methylene-butanedioicaci
NSC 3357
EINECS 202-599-6
Methylenesuccinate
UNII-Q4516562YH
ITN
Methylenebutanedioate
2-Methylenesuccinate
Methylensuccinic Acid
Propylenedicarboxylate
2-methylenebutanedioate
Itaconic acid, >=99%
bmse000137
Probes1_000076
Probes2_000247
EC 202-599-6
2-Methylenesuccinic acid #
ITACONIC ACID [MI]
NCIStruc1_001783
NCIStruc2_000502
2-methylene-butanedioic acid
NCIOpen2_004822
SCHEMBL21523
ITACONIC ACID [INCI]
2-Propene-1,2-dicarboxylate
Itaconic acid, analytical standard
Succinic acid, methylene- (8CI)
HY-Y0520
Tox21_201299
Tox21_303071
BBL011584
BDBM50036216
LMFA01170063
s3095
STL163322
AKOS000118895
2-Hydroxy-3-Naphthoyl-2-Naphthylamine
SB67306
Butanedioic acid,ethylidene-,(E)-(9ci)
NCGC00249019-01
NCGC00257141-01
NCGC00258851-01
AS-11816
CS-0015302
FT-0627543
M0223
EN300-18045
C00490
E80791
Q903311
Z57127539
F2191-0234
2-METHYLENE,1,4-BUTANEDIOIC ACID (ITACONIC ACID)
53EEC7A3-4846-4588-BBC9-CB8846377B96
ITACONIC ACID (METHYLIDENESUCCINIC ACID)

Itaconic acid, also known as methylidenesuccinic acid, is a organic compound with the molecular formula C5H6O4.
Itaconic acid (Methylidenesuccinic acid) is a dicarboxylic acid and an unsaturated compound.
The IUPAC name for itaconic acid is 2-methylidenebutanedioic acid.

CAS Number: 97-65-4
EC Number: 202-599-6

Itaconic acid, Methylidenebutanedioic acid, 2-Methylidenebutanedioic acid, Methylenesuccinic acid, 2-Methylenebutanedioic acid, Dihydroxymethylene succinic acid, Methylenebutanedioic acid, Methylenesuccinic acid, Methylenesuccinic acid, Dihydroxy, Methylenesuccinic acid, cis-Methylenesuccinic acid, Dihydroxydihydrofurandione, Dihydroxy-methylene succinic acid, Methylenesuccinic acid, Methylenesuccinic acid, Maleic acid anhydride, Propylene dicarboxylic acid, Methylenesuccinic acid, Disodium itaconate, 2-Hydroxy-2-methylpropionic acid, 3-Hydroxy-2,2-dimethyl-4-oxobutanoic acid, Itaconnic acid, Acide itaconique, Itakonova kyselina, Itakonsav, Itakonska kiselina, Itakonsyra, Méthylidènebutanedioïque acide, Zouten van itaconzuur, Methylenbutandisaeure, Itakonsav, Itaconnic acid, Itaconic acid



APPLICATIONS


Itaconic acid (Methylidenesuccinic acid) finds extensive use as a precursor in the production of various polymers.
One notable application is its role in the synthesis of polyitaconic acid, a polymer with diverse applications.

Itaconic acid (Methylidenesuccinic acid) is employed in the creation of poly(methyl methacrylate), a widely used transparent plastic.
Itaconic acid (Methylidenesuccinic acid) serves as a monomer in the preparation of copolymers with other compounds for tailored properties.

Itaconic acid (Methylidenesuccinic acid) has applications in the formulation of superabsorbent polymers used in diapers and hygiene products.
Itaconic acid (Methylidenesuccinic acid) is utilized in the creation of resins and coatings with enhanced performance characteristics.

In the textile industry, it contributes to the development of coatings for fabrics and fibers.
Itaconic acid (Methylidenesuccinic acid) is explored for its potential in the production of biodegradable polymers, aligning with sustainable practices.
Itaconic acid (Methylidenesuccinic acid) is employed in the synthesis of graft copolymers with improved material properties.

Itaconic acid (Methylidenesuccinic acid) plays a role in the development of adhesives with enhanced bonding characteristics.
Itaconic acid (Methylidenesuccinic acid) finds applications in the creation of ion-exchange resins for water treatment processes.

In the pharmaceutical industry, Itaconic acid (Methylidenesuccinic acid) is used in the production of controlled-release drug formulations.
Itaconic acid (Methylidenesuccinic acid) is investigated for its use in the creation of biocompatible materials for medical applications.

Itaconic acid (Methylidenesuccinic acid) contributes to the development of eco-friendly and sustainable packaging materials.
Itaconic acid (Methylidenesuccinic acid) is employed in the preparation of biodegradable and water-soluble polymers for diverse applications.
Itaconic acid (Methylidenesuccinic acid) is utilized in the development of coatings for controlled-release fertilizers in agriculture.
In the cosmetic and personal care industry, it is used in the formulation of certain skincare products.

Itaconic acid (Methylidenesuccinic acid) has applications in the creation of specialty chemicals and additives for various industries.
Itaconic acid (Methylidenesuccinic acid) is explored for its use in the production of bio-based plastics with reduced environmental impact.

Itaconic acid (Methylidenesuccinic acid) is employed in the synthesis of environmentally friendly alternatives to traditional petroleum-based materials.
In the field of dentistry, it is studied for potential applications in the development of dental materials.
Itaconic acid (Methylidenesuccinic acid) contributes to the creation of materials with enhanced thermal and mechanical properties.

Itaconic acid (Methylidenesuccinic acid) is utilized in the preparation of water-soluble polymers for industrial processes.
Itaconic acid (Methylidenesuccinic acid) finds applications in the creation of coatings for controlled drug release in medical devices.
Its versatility allows for applications in research, serving as a building block for innovative materials and technologies.

Itaconic acid (Methylidenesuccinic acid) is employed in the production of biodegradable and environmentally friendly plastics.
Itaconic acid (Methylidenesuccinic acid) finds applications in the creation of water-soluble polymers for various industrial processes.
Itaconic acid (Methylidenesuccinic acid) contributes to the development of adhesives with improved strength and durability.

In the field of wastewater treatment, it is used in the formulation of flocculants for solid-liquid separation.
Itaconic acid (Methylidenesuccinic acid) is utilized in the synthesis of polymers with enhanced rheological properties for specific applications.
Itaconic acid (Methylidenesuccinic acid) plays a role in the creation of ion-sensitive hydrogels used in controlled drug delivery systems.

Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the production of conductive polymers for electronics.
Itaconic acid (Methylidenesuccinic acid) is utilized in the development of biocompatible materials for tissue engineering and medical implants.

Itaconic acid (Methylidenesuccinic acid) contributes to the creation of coatings for controlled drug release in pharmaceuticals.
In the food industry, Itaconic acid (Methylidenesuccinic acid) is employed as a chelating agent and stabilizer for certain food products.
Itaconic acid (Methylidenesuccinic acid) finds applications in the formulation of corrosion inhibitors for metal protection.
Itaconic acid (Methylidenesuccinic acid) is used in the creation of specialty chemicals such as plasticizers and surfactants.

Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the development of bio-based lubricants.
Itaconic acid (Methylidenesuccinic acid) contributes to the creation of bio-based and sustainable alternatives to traditional petroleum-derived chemicals.
Itaconic acid (Methylidenesuccinic acid) is employed in the preparation of water-based paints and coatings for eco-friendly applications.
Itaconic acid (Methylidenesuccinic acid) is utilized in the development of biomaterials for drug delivery and medical applications.

Itaconic acid (Methylidenesuccinic acid) plays a role in the creation of environmentally friendly inks and dyes.
Itaconic acid (Methylidenesuccinic acid) is explored for its use in the development of bio-based and biodegradable detergents.

Itaconic acid (Methylidenesuccinic acid) contributes to the production of bio-based plasticizers for polymeric materials.
Itaconic acid (Methylidenesuccinic acid) finds applications in the creation of responsive materials for sensors and actuators.
In the oil and gas industry, it is used in the formulation of chemicals for enhanced oil recovery.
Itaconic acid (Methylidenesuccinic acid) is employed in the creation of specialty coatings for corrosion protection in various industries.
Itaconic acid (Methylidenesuccinic acid) plays a role in the formulation of polymers with stimuli-responsive behavior.

Itaconic acid (Methylidenesuccinic acid) is utilized in the development of bio-based and sustainable materials for 3D printing.
Itaconic acid (Methylidenesuccinic acid) contributes to the research and development of innovative materials with diverse applications across industries.

Itaconic acid (Methylidenesuccinic acid) is utilized in the creation of environmentally friendly and sustainable adhesives.
Itaconic acid (Methylidenesuccinic acid) plays a crucial role in the formulation of biodegradable and water-soluble films.
Itaconic acid (Methylidenesuccinic acid) finds applications in the production of bio-based and eco-friendly detergents.

In the field of agriculture, it is employed in the development of environmentally sustainable agrochemicals.
Itaconic acid (Methylidenesuccinic acid) contributes to the creation of polymers used in the manufacturing of biodegradable packaging materials.
Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the production of bio-based and non-toxic herbicides.

Itaconic acid (Methylidenesuccinic acid) is used in the synthesis of polymers with applications in controlled drug release systems.
Itaconic acid (Methylidenesuccinic acid) finds utility in the creation of bio-based and sustainable materials for water treatment.

Itaconic acid (Methylidenesuccinic acid) is employed in the formulation of coatings for controlled-release fertilizers in agricultural practices.
Itaconic acid (Methylidenesuccinic acid) plays a role in the development of environmentally friendly and sustainable paints and coatings.
Itaconic acid (Methylidenesuccinic acid) contributes to the creation of biomaterials with applications in tissue engineering.
In the textile industry, it is utilized in the creation of sustainable finishes for fabrics.

Itaconic acid (Methylidenesuccinic acid) is explored for its use in the development of bio-based and eco-friendly lubricants.
Itaconic acid (Methylidenesuccinic acid) is employed in the formulation of bio-based and sustainable drilling fluids in the oil and gas sector.
Itaconic acid (Methylidenesuccinic acid) plays a role in the creation of bio-based and non-toxic corrosion inhibitors.

Itaconic acid (Methylidenesuccinic acid) is used in the development of sustainable and eco-friendly fuel additives.
Itaconic acid (Methylidenesuccinic acid) contributes to the formulation of bio-based and environmentally friendly hydraulic fluids.
In the field of cosmetics, it is explored for its use in the development of sustainable skincare products.

Itaconic acid (Methylidenesuccinic acid) finds applications in the creation of bio-based and non-toxic cleaning agents.
Itaconic acid (Methylidenesuccinic acid) is utilized in the production of sustainable and biodegradable mulching films for agriculture.

Itaconic acid (Methylidenesuccinic acid) contributes to the formulation of eco-friendly and biodegradable coatings for food packaging.
Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the creation of sustainable and biocompatible medical implants.
Itaconic acid (Methylidenesuccinic acid) plays a role in the synthesis of bio-based and non-toxic plasticizers for polymers.

Itaconic acid (Methylidenesuccinic acid) is used in the formulation of bio-based and eco-friendly inks for printing applications.
Itaconic acid (Methylidenesuccinic acid) contributes to ongoing research efforts aimed at developing sustainable solutions across various industries.

Itaconic acid (Methylidenesuccinic acid) is employed in the formulation of bio-based and environmentally friendly anti-scaling agents for water treatment.
Itaconic acid (Methylidenesuccinic acid) finds applications in the creation of sustainable and biodegradable soil conditioners for agriculture.
Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the development of eco-friendly and non-toxic corrosion-resistant coatings.
In the realm of biomaterials, it is utilized for creating bio-based and biocompatible scaffolds for tissue regeneration.

Itaconic acid (Methylidenesuccinic acid) contributes to the formulation of sustainable and non-toxic de-icing agents for winter road maintenance.
Itaconic acid (Methylidenesuccinic acid) plays a role in the development of bio-based and environmentally friendly flame retardants for materials.

In the construction industry, it is used in the formulation of sustainable and fire-resistant building materials.
Itaconic acid (Methylidenesuccinic acid) is employed in the creation of bio-based and non-toxic concrete admixtures for construction applications.
Itaconic acid (Methylidenesuccinic acid) finds applications in the production of eco-friendly and biodegradable polymeric films for food packaging.

Itaconic acid (Methylidenesuccinic acid) contributes to the formulation of sustainable and non-toxic ink resins for printing applications.
Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the development of bio-based and environmentally friendly lubricating oils.
In the synthesis of bio-based polymers, it is utilized to create sustainable and high-performance materials for various industries.
Itaconic acid (Methylidenesuccinic acid) is employed in the formulation of eco-friendly and non-toxic pest control agents for agriculture.

Itaconic acid (Methylidenesuccinic acid) plays a role in the creation of sustainable and biodegradable surfactants for cleaning products.
Itaconic acid (Methylidenesuccinic acid) is used in the development of bio-based and non-toxic foaming agents for various applications.
Itaconic acid (Methylidenesuccinic acid) contributes to the formulation of sustainable and non-toxic plastic additives for enhancing material properties.

Itaconic acid (Methylidenesuccinic acid) is explored for its use in the creation of bio-based and environmentally friendly textiles and fabrics.
In the automotive industry, it is employed in the formulation of bio-based and non-toxic additives for lubricants and coolants.

Itaconic acid (Methylidenesuccinic acid) plays a role in the development of sustainable and non-toxic coatings for automotive applications.
Itaconic acid (Methylidenesuccinic acid) is used in the creation of bio-based and environmentally friendly adhesives for wood and composite materials.

Itaconic acid (Methylidenesuccinic acid) contributes to the formulation of sustainable and non-toxic sealants for construction applications.
Itaconic acid (Methylidenesuccinic acid) finds applications in the production of eco-friendly and non-toxic colorants for various industries.

Itaconic acid (Methylidenesuccinic acid) is explored for its potential use in the development of bio-based and sustainable leather tanning agents.
In the electronics industry, it is employed in the formulation of bio-based and non-toxic additives for electronic materials.
Itaconic acid (Methylidenesuccinic acid) plays a role in the creation of sustainable and non-toxic additives for the manufacturing of renewable energy devices.



DESCRIPTION


Itaconic acid, also known as methylidenesuccinic acid, is a organic compound with the molecular formula C5H6O4.
Itaconic acid (Methylidenesuccinic acid) is a dicarboxylic acid and an unsaturated compound.
The IUPAC name for itaconic acid is 2-methylidenebutanedioic acid.

Itaconic acid (Methylidenesuccinic acid) is a crystalline, white, odorless solid at room temperature.
Itaconic acid (Methylidenesuccinic acid) is known for its unsaturated nature due to the presence of a double bond in its molecular structure.

Itaconic acid (Methylidenesuccinic acid) has a chemical formula of C5H6O4, reflecting its composition as a five-carbon organic compound.
Itaconic acid (Methylidenesuccinic acid) is soluble in water, contributing to its versatility in various applications.

Itaconic acid (Methylidenesuccinic acid) is derived from certain fungi, particularly in the Aspergillus genus, where it occurs naturally.
In industrial processes, Itaconic acid (Methylidenesuccinic acid) is often produced through fermentation, using microorganisms like Aspergillus terreus.

Itaconic acid (Methylidenesuccinic acid) serves as a precursor in the synthesis of polymers, contributing to the production of biodegradable materials.
Itaconic acid (Methylidenesuccinic acid) is recognized for its potential in the development of sustainable and environmentally friendly products.

Itaconic acid (Methylidenesuccinic acid) exhibits two carboxylic acid groups, making it a dicarboxylic acid with acidic properties.
Itaconic acid (Methylidenesuccinic acid) is employed in the synthesis of various chemicals, showcasing its versatility in organic chemistry.
Itaconic acid (Methylidenesuccinic acid) has found applications in the production of certain resins and coatings.

Itaconic acid (Methylidenesuccinic acid) is a key component in the creation of polyitaconic acid and poly(methyl methacrylate), important polymers in the industry.
Its structure features a double bond between carbon atoms, contributing to its role as a building block in chemical synthesis.
Itaconic acid (Methylidenesuccinic acid) is investigated for its potential use in the development of biodegradable polymers, aligning with sustainable practices.

Itaconic acid (Methylidenesuccinic acid) is known for its mild acidic properties and is considered safe for certain applications in personal care products.
Itaconic acid (Methylidenesuccinic acid) has been studied for its role in the creation of environmentally friendly alternatives to traditional plastics.

Itaconic acid (Methylidenesuccinic acid) is characterized by its stable solid form, making it suitable for various processing methods.
Itaconic acid (Methylidenesuccinic acid) contributes to the creation of polymers with unique properties, such as high biodegradability.
Its molecular structure includes a distinctive methylene group, influencing its reactivity in chemical reactions.

The versatility of Itaconic acid (Methylidenesuccinic acid) extends to its applications in both academia and industrial settings.
Itaconic acid (Methylidenesuccinic acid) exhibits potential as a platform chemical for the development of new materials and products.
Itaconic acid (Methylidenesuccinic acid) has gained attention for its role in sustainable practices, addressing environmental concerns in the chemical industry.

Itaconic acid (Methylidenesuccinic acid) is an essential component in the research and development of green and bio-based technologies.
Its biocompatibility has made it a subject of interest in various fields, including medical and pharmaceutical research.
Itaconic acid, with its unique properties, stands at the forefront of innovations aimed at creating more sustainable and eco-friendly materials.



PROPERTIES


Chemical Formula: C5H6O4
Molecular Weight: 130.10 g/mol
Appearance: Crystalline, white, odorless solid
Solubility: Soluble in water
Melting Point: Approximately 165-168°C
Boiling Point: Decomposes before boiling
Density: 1.45 g/cm³
pH: Typically acidic
Structural Feature: Contains a double bond in its molecular structure, making it unsaturated
Functional Groups: Dicarboxylic acid with two carboxylic acid groups (-COOH)
Isomeric Forms: Exists in cis and trans isomeric forms due to the presence of the double bond.
Biodegradability: Exhibits biodegradability, making it environmentally friendly.
Reactivity: Exhibits reactivity in polymerization reactions.
Source: Can be derived from certain fungi, particularly Aspergillus terreus, or produced synthetically.



FIRST AID


Inhalation:

If Itaconic acid fumes are inhaled, move the affected person to an area with fresh air.
If the person is experiencing difficulty breathing, provide artificial respiration.
Seek medical attention promptly, especially if respiratory symptoms persist.


Skin Contact:

Remove contaminated clothing and immediately wash the affected skin with plenty of water.
Use mild soap if available and rinse thoroughly.
If irritation or redness persists, seek medical attention.
Contaminated clothing should be removed and washed before reuse.


Eye Contact:

Flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open.
Seek immediate medical attention if irritation, redness, or other symptoms persist.
Remove contact lenses if present and easily removable after the initial flushing.


Ingestion:

If Itaconic acid is ingested, do not induce vomiting unless directed to do so by medical personnel.
Rinse the mouth thoroughly with water if the person is conscious and able to swallow.
Seek medical attention immediately.
Provide medical personnel with information on the quantity ingested, the time of ingestion, and the person's overall health condition.


General First Aid Tips:

Always wear appropriate personal protective equipment (PPE) when working with or handling Itaconic acid to minimize the risk of exposure.
If providing first aid, ensure your safety first and avoid direct contact with the chemical.
Keep emergency contact information, including the number for poison control, readily available in the workplace.
If someone exhibits signs of distress or severe symptoms, call for emergency medical assistance immediately.
Follow any additional first aid measures recommended by medical professionals based on the specific circumstances of exposure.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear appropriate PPE, including chemical-resistant gloves, safety goggles, and a laboratory coat or protective clothing.
Use a fume hood or work in a well-ventilated area to minimize inhalation exposure.

Avoidance of Contact:
Minimize skin contact and avoid eye contact with Itaconic acid.
In case of potential exposure, wash hands thoroughly with soap and water before eating, drinking, or using the restroom.

Inhalation Precautions:
Use local exhaust ventilation systems to control airborne concentrations.
If working with high concentrations, consider using respiratory protection equipment.

Storage Temperature:
Store Itaconic acid in a cool, dry place away from heat sources.
Maintain temperatures within the recommended range to prevent degradation.

Handling Equipment:
Use corrosion-resistant equipment and containers, such as those made of stainless steel or glass.
Ensure that all handling equipment is in good condition to prevent leaks or spills.

Avoid Mixing:
Avoid mixing Itaconic acid with incompatible substances, such as strong bases, reducing agents, and reactive metals.

Emergency Equipment:
Have emergency equipment, such as an eye wash station and safety shower, readily available in the work area.


Storage:

Container Type:
Store Itaconic acid in tightly sealed containers to prevent moisture absorption and contamination.
Use containers made of materials compatible with the chemical.

Separation:
Store Itaconic acid away from incompatible materials to prevent cross-contamination.

Labeling:
Clearly label storage containers with the chemical name, hazard information, and handling instructions.

Ventilation:
Provide adequate ventilation in storage areas to prevent the buildup of fumes or vapors.

Temperature Control:
Avoid exposure to extreme temperatures.
Store Itaconic acid within the recommended temperature range to maintain stability.

Security Measures:
Restrict access to storage areas and keep Itaconic acid out of reach of unauthorized personnel.
Implement proper security measures to prevent theft or intentional misuse.

Spill Response:
Have spill response materials, such as absorbent pads and neutralizing agents, readily available in storage areas.
Train personnel on proper spill response procedures and evacuation protocols.

Regular Inspections:
Conduct regular inspections of storage areas to ensure containers are in good condition, labeled correctly, and there are no signs of leaks or spills.
İMIDAZOLINLER 
isopropyl myristate; Tetradecanoic acid 1-methylethyl ester; Estergel; Myristic Acid, Isopropyl Ester; Bisomel; Tegester; Tetradecanoic Acid, Isopropyl; cas no: 110-27-0; 1405-98-7
İZOBUTANOL
Isopropyl Alcohol; Dimethylcarbinol; sec-Propyl alcohol; Rubbing alcohol; Petrohol; 1-Methylethanol; 1-Methylethyl alcohol; 2-Hydroxypropane; 2-Propyl alcohol; Isopropyl alcohol; Propan-2-ol; IPA; 2-Propanol; Alcool Isopropilico (Italian); Alcool Isopropylique (French); I-Propanol (German); I-Propylalkohol (German); Iso-Propylalkohol (German); cas no: 67-63-0
İZOPROPIL ALKOL
Nom INCI : JOJOBA ALCOHOL Classification : Alcool Ses fonctions (INCI) Emollient : Adoucit et assouplit la peau Agent d'entretien de la peau : Maintient la peau en bon état Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques
JARPOL PVP/VA 64W SOLUTION
DESCRIPTION:
Jarpol PVP/VA 64W Solution is a copolymer of vinylpyrrolidone with vinyl acetate in an an easy-to-use aqueous solution. preserved with 0.05% max. dodecyl trimethyl ammonium chloride.
Jarpol PVP/VA 64W Solution is an excellent film-former and hair styling agent.

CAS No.: 25086-89-9


Jarpol PVP/VA 64W Solution acts as a film forming agent.
Jarpol PVP/VA 64W Solution is 50% aqueous solution of vinylpyrrolidone with vinyl acetate.
Jarpol PVP/VA 64W Solution has strong cohesive properties.
Jarpol PVP/VA 64W Solution provides transparent, hard, glossy, water-removable film.


Jarpol PVP/VA 64W Solution shows compatibility with modifiers & plasticizers allowing variations of hydroscopicity and film flexibility.
Jarpol PVP/VA 64W Solution is suitable for aerosol and non-aerosol products.
Jarpol PVP/VA 64W Solution is recommended for hair styling applications such as hair spray, hair gel, mousses, hair-setting lotions and sculpting gels.



VP/VA Copolymers Jarpol PVP/VA 64W Solution produce transparent, flexible, oxygen permeable films which adhere to glass, plastics and metals.
Jarpol PVP/VA 64W Solution resins are linear, random copolymers produced by the free-radical polymerization of the monomers in diferrent ratios.

Jarpol PVP/VA 64W Solution are available as white powders or clear solutions in ethanol and water.
Jarpol PVP/VA 64W Solution are widely used as film formers because of their film flexibility, good adhesion, luster, water remoistenability and hardness.

These properties make Jarpol PVP/VA 64W Solution suitable for a variety of industrial, personal care and pharmaceutical products.


Jarpol PVP/VA 64W Solution with different rations of N-Vinylpyrrolidone to Vinyl Acetate,soluble in most organic solvents.


Which exists in powder,water solution and ethnol solution form.
Jarpol PVP/VA 64W Solution aqueous solutions are non-ionic, neutralization not required.
Resultant films are hard, glossy, and water-removable; Tunable viscosity, softening point and water sensitivity depending on VP/VA ratio; Good compatibility with many modifiers, plasticizers, spray propellants and other cosmetic ingredients,and the hydroscopicity decreases in proportion to the ration of Vinyl acetate.


APPLICATIONS OF JARPOL PVP/VA 64W SOLUTION:

Jarpol PVP/VA 64W Solution is the excellent choice as film forming agent and hair-styling agent,which are suitable for fourmulations which used as film forming and viscosity modification,especially in hair styling products, such as Hair Gels,Aerosol gas sprays,Wet look sprays.



Jarpol PVP/VA 64W Solution is a 6:4 linear random copolymer of N-vinylpyrrolidone and vinyl acetate.
The vinyl acetate component of Jarpol PVP/VA 64W Solution reduces the hydrophilicity and glass transition temperature (Tg) compared to povidone homopolymers of similar molecular weight.

As a result, Jarpol PVP/VA 64W Solution is the ultimate tablet binder that extends its excellent adhesive property in wet granulation, as well as in dry granulation and direct compression.
Due to its spherical, hollow particle morphology and high plasticity, Jarpol PVP/VA 64W Solution performs exceptionally well as a binder for direct compression.

In addition, a lower Tg makes Jarpol PVP/VA 64W Solution an ideal polymer matrix for solid dispersions/solutions via hot melt extrusion, which enhances the dissolution of poorly soluble drug actives.

BENEFITS OF JARPOL PVP/VA 64W SOLUTION:
Jarpol PVP/VA 64W Solution has Suitability for use in direct compression, dry granulation, wet granulation, hot melt extrusion, and film coating.
Jarpol PVP/VA 64W Solution has Good flowability

Jarpol PVP/VA 64W Solution has Large surface area due to hollow particle morphology – enhances particle bonding and good compressibility
Jarpol PVP/VA 64W Solution has Ideal glass transition temperature (Tg) for hot melt extrusion



CHEMICAL AND PHYSICAL PROPERTIES OF JARPOL PVP/VA 64W SOLUTION


CAS No.: 25086-89-9
Formula: (C6h9no.C4h6o2)X
Molecular main chain: vp/va copolymer
Color: White
here: vp/va copolymer
applications: personal care



SAFETY INFORMATION ABOUT POLY(1-VINYLPYRROLIDONE-CO-VINYL ACETATE)
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



JEFFAMINE D 2000
Jeffamine D 2000 Jeffamine D 2000 Amine is an extremely low vapor pressure difunctional primary amine. Used in epoxy adhesives. Rarely used alone, but rather in conjunction with other curing agents. Jeffamine D 2000 Amine enhances flexibility, toughness and high peel strength. Listed with TSCA, DSL, EINECS/ELINCS, AICS and ENCS. Product Type Crosslinking / Curing / Vulcanizing Agents > Amines /Amides Chemical Composition Polyoxypropylenediamine CAS Number 9046-10-0 JEFFAMINE D 2000 Technical Bulletin JEFFAMINE® D-2000 Polyetheramine JEFFAMINE D-2000 polyetheramine is characterized by repeating oxypropylene units in the backbone. As shown by the representative structure, JEFFAMINE D 2000 polyetheramine is a difunctional, primary amine with average molecular weight of about 2000. The primary amine groups are located on secondary carbon atoms at the end of the aliphatic polyether chains.(x) H2NONH2CH3 CH3x ≈ 33 APPLICATIONS • Key ingredient in the formulation of polyurea and RIM • Co-reactant in epoxy systems which require increased flexibility and toughness BENEFITS • Low viscosity, color and vapor pressure • Improved flexibility from high molecular weight polyether backbone • Increases peel strength SALES SPECIFICATIONS Property Specifications Test Method* Appearance Colorless to pale yellow liquid ST-30.1 with slight haze permitted Color, Pt-Co 25 max. ST-30.12 Primary amine, % of total amine 97 min. ST-5.34 Total acetylatables, meq/g 0.98 – 1.1 ST-31.39 Total amine, meq/g 0.98 – 1.05 ST-5.22 Water, wt% 0.25 max. ST-31.53, 6 Typical Physical Properties AHEW (amine hydrogen equivalent wt.), g/eq 514 Equivalent wt. with isocyanates, g/eq 1030 Viscosity, cSt, 25°C (77°F) 248 Density, g/ml (lb/gal), 25°C 0.991(8.26) Flash point, PMCC, °C (°F) 185 (365) pH, 5% aqueous solution 10.5 Refractive index, nD 20 1.4514 Vapor pressure, mm Hg/°C 0.93/235 4.95/254 At temperatures above 100°F (38oC) Tanks Stainless steel or aluminum Lines, Valves Stainless steel Pumps Stainless steel or Carpenter 20 equivalent Atmosphere Nitrogen JEFFAMINE D 2000 polyetheramine may be stored under air at ambient temperatures for extended periods. A nitrogen blanket is suggested for all storage, however, to reduce the effect of accidental exposure to high temperatures and to reduce the absorption of atmospheric moisture and carbon dioxide. It should be noted that pronounced discoloration is likely to occur at temperatures above 140°F (60oC), whatever the gaseous pad. Cleanout of lines and equipment containing JEFFAMİNE D 2000 polyetheramine can be accomplished using warm water and steam. In the event of spillage of this product, the area may be flushed with water. The proper method for disposal of waste material is by incineration with strict observance of all federal, state, and local regulations. Jeffamine D 2000 is a 2000 MW primary aliphatic polyether diamine based on polyoxypropylenediamine. Jeffamine D-2000 is suitable for use in polyurea coatings, adhesives, sealants and elastomer applications. 247 cps at 25C. Supplied as a light yellow liquid. AHEW: 515 Jeffamine D 2000 is an excellent product. However, it is Tri-iso's opinion that Endamine D 2000 represents a better value overall. Endamine D 2000 is a direct drop-in replacement for Jeffamine D 2000, and is also a 2000MW primary aliphatic diamine based on polyoxypropylenediamine. JEFFAMINE D2000 Polyoxypropylenediamine is an amine-terminated polyoxypropylene diol that has wide use in epoxy and polyurea systems. Jeffamine D 2000 Amine by Huntsman is an extremely low vapor pressure difunctional primary amine. Used in epoxy adhesives. Rarely used alone, but rather in conjunction with other curing agents. Jeffamine D 2000 Amine enhances flexibility, toughness and high peel strength. Listed with TSCA, DSL, EINECS/ELINCS, AICS and ENCS. DOCUMENTS JEFFAMINE® D-2000 Polyoxypropylenediamine Datasheet New Secondary Amine Chain Extenders for Aliphatic Polyurea Materials Physical Properties of Aromatic Polyurea Elastomer Coatings After Exposure to Extreme Conditions The Influence of Isomer Composition and Functionality on the Final Properties of Aromatic Polyurea Spray Coatings Tuning the Properties of Polyurea Elastomer Systems via Raw Material Selection and Processing Parameter Modulation Adhesion Properties of Epoxy Formulations Containing JEFFAMINE Polyetheramine Curing Agents Huntsman Performance Products makes their documentation available in the regions indicated below: JEFFAMINE D 2000 Polyoxypropylenediamine is an amine-terminated polyoxypropylene diol that has wide use in epoxy and polyurea systems. These include amines, such as ethyleneamines and polyetheramines, alkylene carbonates, and a broad spectrum of surfactants and surfactant intermediates. Product applications include dispersants for coatings, amine neutralizers for latex paints, wetting agents, and emulsifiers for polymer dispersion. 248Huntsman Jeffamine D-2000 Home / Chemicals / Jeffamine D-2000 | Quote Request | Polyether Amine Jeffamine D-2000 is a 2000 MW primary aliphatic polyether diamine based on polyoxypropylenediamine. Jeffamine D-2000 is suitable for use in polyurea coatings, adhesives, sealants and elastomer applications. 247 cps at 25C. Supplied as a light yellow liquid. AHEW: 515 Jeffamine D 2000 is an excellent product. However, it is Tri-iso's opinion that Endamine D2000 represents a better value overall. Endamine D2000 is a direct drop-in replacement for Jeffamine D-2000, and is also a 2000MW primary aliphatic diamine based on polyoxypropylenediamine. Jeffamine D-2000 Amine It is a kind of polyalkane epoxy compound terminated by primary Amine group or secondary Amine group, its molecular skeleton is polyether and its reactive group is Amine end group. Based on different molecular weights and different numbers of functional groups, there can be various kinds of grades ZD-1200, ZD-140, ZD-123, ZT-143 and ZT-1500. Amine-terminated polyether is the key raw material for spray polyurea elastomer,and it can be widely used to protect the materials such as waterproof and anticorrosion coatings of building concrete and steel structure; and moreover, it can be also used as anti-skid and hard-wearing lining for transportation vehicles, anticorrosive coating for cross-sea bridges, protective decoration for top grade floors at sterile plants and hospitals as well as the walls of high-grade swimming pools, internal and external protective coatings for land and benthal oil pipelines, wear-resistant coatings for decks and screw propellers of ships and boats, antiseptic and rust-proof lining for oil tanks, air tanks and water storage tanks, leakage-proof and antiseptic coatings for temporary parking aprons and activated sludge tanks, leakage-proof, anti-seepage and antiseptic materials for municipal refuse disposal areas, stadiums and runways. In addition of that, it is largely used for water-proof and protective coatings of high-speed railway bridges. Amine-terminated polyether is a kind of curing agent for epoxy resin. It can be used to pour large-scale epoxy resin components to make the cured resin crystal-clear. It can be also widely used in the fields of epoxy composite materials, epoxy coatings,epoxy electrophoretic coatings,binding agents, circuit boards, sealants, artworks, etc. Amine-terminated polyether is a kind of curing agent used on the combined blade materials for wind power generation. Amine-terminated polyether is an additive for gasoline, diesel and lubricating oil.And meanwhile, it is widely employed in the fields of surface active agents, water-soluble paints and so on. ZD-123 Amine-terminated polyether is a kind of polypropylene oxide compound mainly terminated by secondary Amine group. It structure is shown as follows: Molecular weight Wn About 230 Degree of functionality ~2 Total amine value MEQ/g 8.10-9.10 Rate of primary Amine group % ≥95 Color APHA ≤25 Moisture % ≤0.25 Applications: ●Curing agent for epoxy resin; curing agent for ornament glue (hard glue); curing agent for wind blade adhesive; ●hot-melt adhesive for polyamide; curing agent for electron end-sealing material; ●curing agent for electron potting compound; curing agent for electron encapsulating material ●fast curing RIM; curing agent for building structure adhesive; ●curing agent for modified polyether amine; ●curing agent for heavy anti-corrosion coatings; ●curing agent for composite materials of fishing rods, golf clubs and tennis rackets. Properties: ● low viscosity, low chromaticity and low vapor pressure.
JEFFAMINE D-2010
DESCRIPTION:
JEFFAMINE D-2010 polyetheramine is characterized by repeating oxypropylene units in the backbone.
As shown by the representative structure, JEFFAMINE D-2010 polyetheramine is a difunctional, primary amine with average molecular weight of about 2000.

The primary amine groups are located on secondary carbon atoms at the end of the aliphatic polyether chains.
JEFFAMINE D-2010 is a key ingredient in the formulation of polyruea and RIM, and can be used as a co-reactant in epoxy systems which require increased flexibility and toughness.


JEFFAMINE D-2010 polyetheramine is characterized by repeating oxypropylene units in the backbone.
As shown by the representative structure, JEFFAMINE D-2000 polyetheramine is a difunctional, primary amine with average molecular weight of about 2000.
The primary amine groups are located on secondary carbon atoms at the end of the aliphatic polyether chains.


APPLICATIONS OF JEFFAMINE D-2010:
JEFFAMINE D-2010 is Key ingredient in the formulation of polyurea and RIM
JEFFAMINE D-2010 is Co-reactant in epoxy systems which require increased flexibility and toughness

BENEFITS OF JEFFAMINE D-2010:
JEFFAMINE D-2010 has Low viscosity, color and vapor pressure
JEFFAMINE D-2010 has Improved flexibility from high molecular weight polyether backbone
JEFFAMINE D-2010 Increases peel strength



TYPICAL PHYSICAL PROPERTIES OF JEFFAMINE D-2010:
AHEW (amine hydrogen equivalent wt.), g/eq 514
Equivalent wt. with isocyanates, g/eq 1030
Viscosity, cSt, 25°C (77°F) 248
Density, g/ml (lb/gal), 25°C 0.991(8.26)
Flash point, PMCC, °C (°F) 185 (365)
pH, 5
% aqueous solution 10.5
Refractive index, nD 20 1.4514
Vapor pressure, mm Hg/°C 0.93/235 4.95/254
Appearance: Colorless to pale yellow liquid with slight haze permitted Color,
Pt-Co 25 max.
Primary amine, % of total amine 97 min.
Total acetylatables, meq/g 0.98 – 1.1
Total amine, meq/g 0.98 – 1.05
Water, wt% 0.25 max.



SAFETY INFORMATION ABOUT JEFFAMINE D-2010:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product
JEFFAMINE T-5000
Jeffamine T-5000 is a trifunctional primary amine.
Jeffamine T-5000 is a colorless to light yellow liquid at room temperature with a molecular weight of approximately 5,000.


CAS Number: 64852-22-8
MDL Number:MFCD00804529
INCI/Chemical Name: Glyceryl poly(oxy propylene)triamine
Product Type: Adhesion Promoters > Polyethylenimines
Chemical Composition: Polyetheramine
Chemical Name: Polyetheramine
Molecular Formula: (C3H6O)mult(C3H6O)mult(C3H6O)multC



alpha,alpha',alpha''-1,2,3-propanetriyltris(omega-(2-aminomethylethoxy)-poly(oxy(methyl-1,2-ethanediyl)), JEFFAMINE T5000, T-5000 polyetheramine equivalent, Polypropylene glycol bis(2-aminopropyl ether), polyetheramine, Polyetheramines, 2-(aminooxy)propan-1-amine, POLYETHERAMINE T 5000, [omega-(2-aminomethylethoxy)-, Polyetheramine T5000 (Baxxodur, glyceroltris(poly(propyleneglycol), ZT-1500 Amine-terminated Polyether, Glyceryl poly(oxypropylene)triamine, POLY(PROPYLENE OXIDE), TRIAMINE TERMITED, POLY(PROPYLENE OXIDE), TRIAMINE TERMINATED, glycerol tris(poly(propylene glycol)amine terminated), 2-aminopropan-1-ol,propane-1,2-diol,propane-1,2,3-triol, POLYETHERAMINE T 5000, POLY(PROPYLENE OXIDE), TRIAMINE TERMINATED, [omega-(2-aminomethylethoxy)-, 2-ethanediyl)],.alpha.,.alpha.',.alpha.''-1,2,3-propanetriyltris[.omega.-(2-aminomethylethoxy)-Poly[oxy(methyl-1, glyceroltris(poly(propyleneglycol), GLYCEROL TR, JeffamineT 3000, Jeffamine T 5000, T 5000, XTJ 509, lyceroltris (poly (propyleneglycol), GLYCEROL TRIS [POLY (PROPYLENE GLYCOL), AMINE TERMINATED] ETHER, Polyoxy (methyl-1,2-ethanediyl), a.,.alpha.,.alpha-1,2,3-propanetriyltris .omega .-(2-aminomethylethoxy)-, Glyceryl poly(oxypropylene)triamine, Poly[oxy(methyl-1,2-ethanediyl)],α,α,′,α”-1,2,3-propanetriyltris[ω - (2-aminomethyl-ethoxy) -, Polyetheramine T5000 (Baxxodur, POLY (PROPYLENE OXIDE), TRIAMINE TERMITED, POLYETHERAMINE T 5000,



Jeffamine T-5000 provides flexibility and promotes adhesion as a co-reactant in epoxy systems.
Benefits of Jeffamine T-5000 include increased peel strength, toughness and low colour.
Jeffamine T-5000 is a trifunctional primary amine.


Jeffamine T-5000 is a colorless to light yellow liquid at room temperature with a molecular weight of approximately 5,000.
Jeffamine T-5000 is compatible with a variety of organic solvents.
Jeffamine T-5000 has surface corrosion resistance performance in epoxy-polyurethane systems.


Jeffamine T-5000 is equivalent.
Jeffamine T-5000's a trifunctional primary amine of approximately 5000 molecular weight.
Jeffamine T-5000 is clear, almost colorless, viscous, liquid product.


Jeffamine T-5000 is a colorless or yellowish liquid
Jeffamine T-5000 is a kind of polypropylene oxide, mainly terminated by primary amino group.
Jeffamine T-5000 is a primary polyetheramine with trifuctionarity. Jeffamine T-5000's molecular weight is about 5,000.


Jeffamine T-5000 is a clear, almost colorless, viscous, liquid product.
Jeffamine T-5000 is a 5000 MW primary trifunctional aliphatic polyether amine.
Jeffamine T-5000 is suitable for use in polyurea coatings, adhesives, sealants and elastomer applications, as well as in epoxy systems. 819 cps at 25C.


Jeffamine T-5000 is supplied as a clear, almost colorless viscous liquid. AHEW: 952, Equivalent weight with Isocyanates: 1904
Jeffamine T-5000 is an excellent product.
However, Jeffamine T-5000 is Tri-iso's opinion that Endamine T5000 represents a better value overall.


Endamine T5000 is a direct drop-in replacement for Jeffamine T5000, and is also a 5000MW primary trifunctional aliphatic amine.
Jeffamine T-5000 is a 5000 molecular weight polyoxypropylene triamine that can be added to a variety of curing agents to impart flexibility and improve peel strength of the adhesive systems with little degradation in other properties.


Jeffamine T-5000 is a trifunctional primary amine of approximately 5000 molecular weight.
Jeffamine T-5000 is clear, almost colorless, viscous, liquid product.
Jeffamine T-5000 is polyetheramine by Huntsman.


Jeffamine T-5000 is a crosslinker for polyurea and co-reactant in epoxy systems.
Jeffamine T-5000 offers benefits such as increased peel strength, low color and increased toughness.
Jeffamine T-5000 is a trifunctional primary amine of approximately 5000 molecular weight.


Jeffamine T-5000 is clear, almost colorless, viscous, liquid product.
Jeffamine T-5000 is a 5000 MW primary trifunctional aliphatic polyether amine.
Jeffamine T-5000 is supplied as a clear, almost colorless viscous liquid. AHEW: 952, Equivalent weight with Isocyanates: 1904


Jeffamine T-5000 is an excellent product.
However, Jeffamine T-5000 is Tri-iso's opinion that Endamine
T5000 represents a better value overall.


It is a direct drop-in replacement for Jeffamine T-5000, and is also a 5000MW primary trifunctional aliphatic amine.
Jeffamine T-5000 is a trifunctional primary polyetheramine of approximately 5000 molecular weight used as crosslinker for polyurea, co-reactant in epoxy systems where adhesion promotion and flexibility are important.



USES and APPLICATIONS of JEFFAMINE T-5000:
Jeffamine T-5000 is used epoxy curing agent.
Jeffamine T-5000 is used co-reactant in epoxy system where adhesion promotion and flexibility are important.
Jeffamine T-5000 is used a spray cross-linking agent for polyurea.


Jeffamine T-5000 is used Surfactant.
Jeffamine T-5000 is used corrosion inhibitor.
Jeffamine T-5000 is used as a co-reactant in epoxy resin systems where promoting adhesion and flexibility is important.


Jeffamine T-5000 is a cross-linker for polyureas and co-reactants in epoxy systems.
Jeffamine T-5000 offers the benefits of increased peel strength, low color and increased toughness.
Jeffamine T-5000 is a reactive chain extender for polyurethane with typical primary amine reaction properties.


Jeffamine T-5000 is widely used in the polyurethane RIM industry and is the main raw material for spray polyurea elastomer.
Because of its unique chemical structure, Jeffamine T-5000 plays a toughening role in the epoxy industry.
Together with polyamide, Jeffamine T-5000 is used in epoxy adhesives characterized by high strength.


Jeffamine T-5000 has surface anti-corrosion effect in epoxy-polyurethane system.
Jeffamine T-5000 is used spraying polyurea crosslinking agent, modified polyether amine curing agent; Hardener for high pressure FRP pipe (amine pipe); Curing agent of epoxy resin for fishing rod, golf club and tennis racket composite materials; Surfactants, corrosion inhibitors, etc.


Jeffamine T-5000 is an active chain extender for polyurethane with typical reaction properties of primary amine.
Jeffamine T-5000 is widely used in the polyurethane RIM industry as the main raw material of Spray Polyurea Elastomer.
Because of its characteristic structure, Jeffamine T-5000 has a good toughening effect in the epoxy resin industry.


Together with polyamides, Jeffamine T-5000 can also be used in highly intensive epoxy adhesives.
Jeffamine T-5000 undergoes typical amine reactions that often yield increased flexibility, toughness, low viscosity, and low color.
Jeffamine T-5000 has a wide range of molecular weight, amine functionality, repeating unit type and distribution can provide flexibility in the design of new compounds or mixtures.


Jeffamine T-5000 is used as an auxiliary reactant in epoxy systems where adhesion promotion and flexibility are important.
Jeffamine T-5000 is a crosslinker for polyurea and co-reactant in epoxy systems.
Jeffamine T-5000 offers benefits such as increased peel strength, reduced color and increased toughness.


Jeffamine T-5000 is suitable for use in polyurea coatings, adhesives, sealants and elastomer applications, as well as in epoxy systems.
Jeffamine T-5000 is used Crosslinker for polyurea
Jeffamine T-5000 is used co-reactant in epoxy sytems where adhesion promotion and flexibility are important


Jeffamine T-5000 is used surfactant and corrosion inhibitor applications.
Jeffamine T-5000 is used as a co-reactant in epoxy systems where adhesion promotion and flexibility are important.
Jeffamine T-5000 is used as crosslinker for polyurea, co-reactant in epoxy systems where adhesion promotion and flexibility are important.



APPLICATION ADVANTAGES OF JEFFAMINE T-5000:
*Initial low viscosity of the compositions.
*Jeffamine T-5000 provides wettability of various surfaces, filling hard-to-reach areas and self-leveling.
*High physical and mechanical properties of the polymer.
*Jeffamine-based coatings are resistant to peeling and can withstand heavy loads.
*Moderate reactivity allows for large volumes to be poured.
*Jeffamine T-5000 is possible to obtain an optically transparent polymer.



CHARACTERISTICS OF JEFFAMINE T-5000:
*Low color and vapor pressure
*Enhance peel strength in epoxy adhesives
*Strengthening the bonding force of epoxy resin
*Increase toughness
*Improves flexibility and strength



FEATURES OF JEFFAMINE T-5000:
*Low viscosity and vapor pressure.



BENEFITS OF JEFFAMINE T-5000:
• Low color
• Increased peel strength in epoxy adhesives
• Increased toughness
• Jeffamine T-5000 is one of the basic materials used in polyurea synthesis and RIM (reaction injection molding method).
• Jeffamine T-5000 is used as an auxiliary reactant in epoxy systems.



PHYSICAL and CHEMICAL PROPERTIES of JEFFAMINE T-5000:
Appearance: Colorless to pale yellow liquid
Color, Pt-Co: 50 Max.
Primary amine of total amine: 97% Min.
Total acetylatables: 0.56-0.63mmol/g
Total amine: 0.50-0.54mmol/g
Water: 0.25% Max.
Color number Pt-Co: ≤50
Primary amine content%: ≥97
Acetyl value mmol/g: 0.58-0.63
Amine value mmol/g: 0.50-0.54
Moisture%: ≤0.10
CBNumber:CB1197426
Molecular Formula:C9H25NO6
Molecular Weight:243.2979
MDL Number:MFCD00804529
MOL File:64852-22-8.mol

Density: 1 g/mL at 25 °C(lit.)
refractive index: n20/D 1.453
Flash point: >230 °F
EPA Substance Registry System: Poly[oxy(methyl-1,2-ethanediyl)], .alpha.,.alpha.',.alpha.'
'-1,2,3-propanetriyltris[.omega.-(2-aminomethylethoxy)- (64852-22-8)
Molecular weight: About 5000
Appearance: Colorless to pale yellow liquid
Degree of functionality: ~3
Total amine meq/g: 0.50-0.57
Primary amine %: ≥97
Color, Pt-Co(APAH): ≤50
Water, wt%: ≤0.25
Viscosity cSt,25℃: 819
Density g/ml (lb/gal),25℃: 0.997(8.31)
Solids Content by Weight, %: 18-21
Flash point PMCC,℃(℉): 213(415.4)
PH: 11.2
CAS: 64852-22-8



FIRST AID MEASURES of JEFFAMINE T-5000:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person. Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of JEFFAMINE T-5000:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of JEFFAMINE T-5000:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of JEFFAMINE T-5000:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of JEFFAMINE T-5000:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of JEFFAMINE T-5000:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available


JOJOBA ALCOHOL
Benzyl Alcohol (and) Methylchloroisothiazolinone (and) Methylisothiazolinone CAS NO:185532-71-2
JOJOBA OIL
Jojoba oil is an excellent face and body moisturizer.
Jojoba oil conditions and smooths hair and beards.
Jojoba oil is an ideal carrier for essential oils and as a base for personal care products.


CAS NUMBER: 61789-91-1

EC NUMBER: 612-381-6

MOLECULAR FORMULA: -

MOLECULAR WEIGHT: -

INCI NAME: Hydrogenated Jojoba Oil


Jojoba oil is the liquid produced in the seed of the Simmondsia chinensis plant, a shrub, which is native to southern Arizona, southern California, and northwestern Mexico.
The oil makes up approximately 50% of the jojoba seed by weight.
The terms "Jojoba oil" and "jojoba wax" are often used interchangeably because the wax visually appears to be a mobile oil, but as a wax it is composed almost entirely (~97%) of mono-esters of long-chain fatty acids (wax ester) and alcohols (isopropyl jojobate), accompanied by only a tiny fraction of triglyceride esters.
This composition accounts for its extreme shelf-life stability and extraordinary resistance to high temperatures, compared with true vegetable oils.


Appearance of Jojoba oil:
Unrefined Jojoba oil appears as a clear golden liquid at room temperature with a slightly nutty odor.
Refined Jojoba oil is colorless and odorless. The melting point of jojoba oil is approximately 10 °C (50 °F) and the iodine value is approximately 80
Jojoba oil is relatively shelf-stable when compared with other vegetable oils mainly because it contains few triglycerides, unlike most other vegetable oils such as grape seed oil and coconut oil.
Jojoba oil has an oxidative stability index of approximately 60, which means that it is more shelf-stable than safflower oil, canola oil, almond oil, or squalene but less than castor oil and coconut oil.

Uses:
Being derived from a plant that is slow-growing and difficult to cultivate, Jojoba oil is mainly used for small-scale applications such as pharmaceuticals and cosmetics
Overall, Jojoba oil is used as a replacement for whale oil and its derivatives, such as cetyl alcohol.

Jojoba oil is found as an additive in many cosmetic products, especially those marketed as being made from natural ingredients.
In particular, such products commonly containing jojoba are lotions and moisturizers, hair shampoos and conditioners.
The pure oil itself may also be used on skin, hair, or cuticles.

Like olestra, Jojoba oil is edible but non-caloric and non-digestible, meaning the oil will pass out of the intestines unchanged and can mimic steatorrhea—a health condition characterized by the inability to digest or absorb normal dietary fats.
Thus, Jojoba oil is present in the stool, but does not indicate an intestinal disease.
If consumption of Jojoba oil is discontinued in a healthy person, the indigestible oil in the stool will disappear.

Jojoba oil also contains approximately 12.1% of the fatty acid erucic acid that would appear to have toxic effects on the heart at high enough doses, if it were digestible.
Although impractical, jojoba biodiesel has been explored as a sustainable fuel that can serve as a substitute for petroleum diesel.

Jojoba oil is nontoxic
Jojoba oil is nonallergenic (the extract is pressed from a seed, not a nut, and is safe for consumers with nut allergies), and noncomedogenic since it won't clog pores with its sebum-compatibility.
Being a liquid wax with very low levels of triglycerides, Jojoba oil does not easily oxidize, making it remarkably shelf-stable and able to withstand heat without any loss in its properties, unlike most plant oils.

Jojoba oil is a popular massage medium because of its compatibility with all skin types, its nonallergenic properties, and the fact that a little goes a long way.
Jojoba oil is safe for all ages (which is one reason we created HobaCare Baby) and skin types.

Jojoba oil is actually a liquid wax ester and not an oil.
Although it shares the same consistency as an oil, the Jojoba plant produces wax esters that hold a similar molecular structure to the oils naturally found in our skin.
So, when using Jojoba oil, our body becomes more receptive to vital nutrients and antioxidants, helping our skin balance just as it was designed to do.

BENEFITS:
*Jojoba oil is hypoallergenic
*Jojoba oil has a similar molecular structure to the oils naturally produced in our skin
*Jojoba oil has a wide variety of uses for skin, body, hair & nails
*Jojoba oil soothes sunburns
*Jojoba oil provides 8 hours of moisturisation
*Jojoba oil is non-comedogenic
*Vitamins A, D & E plus omegas 6 & 9
*Extensive shelf life - up to 2 years
*Jojoba oil regulates oil production in skin & hair
*Jojoba oil is a natural emollient
*Jojoba oil has no nasties or additives

Jojoba oil nourishes, moisturizes, and protects skin
Jojoba oil regulates sebum production and preserves skin from aging

Mature jojoba plants are woody perennial bushes that don't shed their leaves when the seasons change.
The chemical structure of organic Jojoba oil is different from that of other vegetable oils because it’s a polyunsaturated wax.

As a wax, Jojoba oil for the face and body is especially useful
Jojoba oil protects the skin

Jojoba oil is providing hydration control
Jojoba oil soothes your hair.

At room temperature, Jojoba oil is liquid because of its unsaturated fatty acids.
Like some natural oils, Jojoba oil does not break down or become rancid.

Jojoba oil actually has a very long shelf life, which makes it good for cosmetic products and applications.
Jojoba oil contains beneficial ingredients

Jojoba oil is including vitamin E, vitamin B complex, silicon, chromium, copper and zinc.
Jojoba oil has a very high percentage of iodine at 82 percent, which gives jojoba oil its power to heal.


GENERAL PROPERTIES:

-Melting Point: 7 ℃

-Boiling Point: 396 ℃

-Flash Point: > 200.00 °F

-Density: 0.87 g/mL at 20 °C

-Vapor Pressure: 0-0Pa at 25 ℃

-Refractive Index: n20/D1.466

-Storage Temperature: 2-8 °C

-Color: Colorless

-Form: Semi-solid (amorphous) or gel

-Specific Gravity: 0.863

-Viscosity Index: 190-230


Jojoba oil is oily liquid in nature
Jojoba oil has a characteristic fatty odor.

Jojoba oil is goldencolored liquid wax, which are produced by the seeds of the jojoba plant
Jojoba oil is used for dry and oily skin.

Jojoba oil regulates the sebum produced on the skin, as the oil can control the greasy texture of the skin.
On dry skin type, Jojoba oil acts as a moisturizer.

Jojoba oil also acts as a lip-balm for dry and chapped lips.
Jojoba oil has many benefits, and is best used for the hair and skin.

Jojoba oil is colorless
Jojoba oil is odorless

Jojoba oil has a waxy liquid form
Jojoba oil is chemically similar to sperm oil.

Jojoba oil is a moisturizer and emollient.
Mystical properties have been attributed to it for its apparent ability to heal the skin.

Jojoba oil reduces transepidermal water loss without completely blocking the transportation of water vapor and gases, providing the skin with suppleness and softness.
In addition, Jojoba oil gives cosmetic products excellent spreadability and lubricity.

Jojoba oil can penetrate rapidly by absorption via the pores and hair follicles.
From these areas, it seems to diffuse into the stratum corneum layer and acts with intercellular lipids to further reduce water loss.

Jojoba oil is not a primary skin irritant and does not promote sensitization.
Jojoba oil is derived from the plant seeds.

Jojoba oil has a straight chain with 36 to 46 carbons.
Jojoba oil is a crystalline, hard wax ester.

Jojoba oil has particular functionality in cosmetics due to its capacity to strengthen the wax matrices of "stick" formulations like lipstick, eyeliner, lip balm, etc.
Jojoba oil is colorless and odorless.

Jojoba oil works as an abrasive scrub
Jojoba oil also used as an emollient

Jojoba oil can be used as a skin-conditioning agent in cosmetics and personal care products.
Jojoba oil is used in lipsticks up to 31% concentration.

Skin care: Jojoba oil functions as an emollient and skin-conditioning agent.
Jojoba oil aids in making the skin softer and smoother.

Jojoba oil has a reputation for being moisturizing because it can improve skin hydration and stop water loss.
Additionally, Jojoba oil is non-greasy and readily absorbed because it shares a chemical structure with the natural oils produced by our skin.

This makes Jojoba oil a well-liked component of numerous skincare products, such as moisturizers, lip balms, and makeup items.
Jojoba oil is often used as a material for exfoliation particles due to its uniform color, hardness, and controllable crystallinity

Jojoba oil is an extract of the Mexican native plant jojoba, which moisturizes, strengthens the skin, softening fat
Jojoba oil has an anti-inflammatory effect.

Jojoba oil is not an oil, but a liquid wax that solidifies at low temperatures.
jojoba oil is not oil, but liquid wax, so it will solidify at low temperature.

Jojoba oil is the most permeable base oil
Jojoba oil is easily absorbed by the skin

Jojoba oil is fresh and moist
Jojoba oil is non-greasy

Jojoba oil can restore the skin pH balance and wrinkles
Jojoba oil effectively improves oily skin

Jojoba oil regulates sebaceous gland secretion function
Jojoba oil shrinks pores

Jojoba oil is also the best skin moisturizing oil.
Jojoba oil film formed by it is different from mineral oil in that it can penetrate the evaporated water and can also control the loss of water.

Jojoba oil is very clear
Jojoba oil smells a light nut flavor
Jojoba oil is very plump, but not as greasy as other vegetable oils


SYNONYM:

Golden Jojoba
JOJOBA OIL REFINED
JOJOBA OIL, UNREFINED
Jojoba bean oil
Jojoba liquid wax
Jojobae oelum
OIL, JOJOBA(RG)
Jojoba oil (Simmondsia chinensis)
jojobaoilfromsimmondsiachinensis
Hydrogenated jojoba oil
724GKU717M
61789-91-1
Jojoba oil
Jojoba oil, hydrogenated
Jojoba wax
Oils, jojoba
Oils, jojoba, hydrogenated
Jojoba bean oil
Waxes and Waxy substances, jojoba
Jojoba liquid wax
E-RASE
FloraEster Jojoba Oil
Jojoba waxy substances
Oils, jojoba-bean
UNII-724GKU717M
florabeads jojoba
florabeads jojoba 10/10
florabeads silkies
floraesters 15
floraesters 20
floraesters 30
floraesters 60
floraesters 70
florapearls
florasomes
floraspheres
hydrogenated jojoba bean oil
jojoba, ext., hydrogenated
nikkol jojoba wax
hydrogenated oils, jojoba-bean
Jojoba oil
Golden Jojoba
jojoba bean oil
OIL, JOJOBA
JOJOBA OIL REFINED
JOJOBA OIL, UNREFINED
jojobaoilfromsimmondsiachinensis
Jojoba oil (Simmondsia chinensis)
jojoba oil from simmondsia chinensis
Jojoba bean oil, Jojoba liquid wax
Jojoba bean oil, Jojoba liquid wax, Jojobae oelum

JORDAPON CI-65

Jordapon CI-65 is a versatile surfactant blend used in personal care formulations.
Jordapon CI-65 combines Sodium Cocoyl Isethionate and Stearic Acid to create a synergistic effect.
With its creamy texture and mild cleansing properties, Jordapon CI-65 is ideal for gentle skincare products.

CAS Number: 61789-32-0, 57-11-4
EC Number: 263-052-5, 200-313-4

SCI/SA, Sodium Cocoyl Isethionate/Stearic Acid blend, Sodium Cocoyl Isethionate and Stearic Acid mixture, Jordapon CI-65 blend, SCI and Stearic Acid surfactant, Sodium Cocoyl Isethionate-Stearic Acid complex, Jordapon CI-65 surfactant blend, SCI with Stearic Acid combination, Sodium Cocoyl Isethionate plus Stearic Acid, Jordapon CI-65 formulation, Sodium Cocoyl Isethionate-Stearic Acid compound, SCI/SA surfactant mix, Jordapon CI-65 chemical combination, Sodium Cocoyl Isethionate blended with Stearic Acid, Jordapon CI-65 ingredient blend, Sodium Cocoyl Isethionate-Stearic Acid composition, SCI and Stearic Acid formulation, Jordapon CI-65 complex, Sodium Cocoyl Isethionate with Stearic Acid mixture, Jordapon CI-65 surfactant combination



APPLICATIONS


Jordapon CI-65 is commonly used in syndet bars, providing gentle cleansing for the skin without stripping away natural oils.
Jordapon CI-65 is utilized in combo bars, offering a blend of cleansing and moisturizing properties in solid soap formulations.
Jordapon CI-65 is incorporated into facial cleansing products, including creams, gels, and foams, for effective removal of impurities while maintaining skin hydration.

Jordapon CI-65 blend finds application in body washes, creating luxurious lather for a refreshing shower experience.
Jordapon CI-65 is added to aerosol shave creams, providing a smooth and comfortable shaving experience by softening facial hair and lubricating the skin.
Jordapon CI-65 is used in facial masks and cleanser pads to enhance the cleansing and exfoliating effects.

Jordapon CI-65 is found in acne treatment products, helping to cleanse pores and reduce excess oil without causing irritation.
The blend is incorporated into intimate hygiene products such as feminine washes, providing gentle cleansing while maintaining pH balance.
Jordapon CI-65 is added to baby care products, including gentle cleansers and diaper creams, for its mildness and skin conditioning properties.

Jordapon CI-65 is used in pet grooming products such as shampoos and conditioners, providing effective cleansing and conditioning for pets' fur and skin.
Jordapon CI-65 is utilized in exfoliating scrubs and body polishes, helping to remove dead skin cells and reveal smoother skin.

Jordapon CI-65 is added to foot care products such as foot scrubs and creams, helping to soften rough skin and soothe tired feet.
Jordapon CI-65 finds application in bath bombs and bath fizzies, creating foamy and aromatic baths for relaxation.
Jordapon CI-65 is incorporated into massage oils and body oils, facilitating smooth application and absorption into the skin.

Jordapon CI-65 is utilized in pre-shave products such as facial scrubs and cleansers, preparing the skin for a closer and smoother shave.
Jordapon CI-65 is added to post-shave products such as balms and lotions, soothing irritation and moisturizing the skin.
Jordapon CI-65 is found in sunless tanning products, helping to distribute the tanning agent evenly for a natural-looking tan.

Jordapon CI-65 is utilized in hair care products such as shampoos and conditioners, providing gentle cleansing and conditioning for all hair types.
Jordapon CI-65 is added to styling products such as mousses and foams, providing hold and volume without weighing down the hair.
Jordapon CI-65 is incorporated into sunscreen formulations, enhancing spreadability and water resistance.

Jordapon CI-65 is utilized in natural and organic personal care products, aligning with consumers' preferences for clean beauty.
Jordapon CI-65 is added to facial mists and sprays, providing hydration and refreshing the skin throughout the day.
Jordapon CI-65 is found in wound care products such as cleansing wipes and antiseptic solutions, facilitating gentle yet effective wound care.

Jordapon CI-65 is utilized in exfoliating lip scrubs and hydrating lip balms, helping to maintain smooth and moisturized lips.
Jordapon CI-65 is a versatile ingredient with applications in various personal care products, offering gentle cleansing, conditioning, and moisturizing properties for the skin and hair.

In facial toners and astringents, Jordapon CI-65 helps to remove excess oil and impurities while toning and tightening the skin.
Jordapon CI-65 is incorporated into facial serums and treatments, assisting in the delivery of active ingredients and improving skin texture.
Jordapon CI-65 is found in anti-aging skincare products such as creams and lotions, helping to reduce the appearance of fine lines and wrinkles.

Jordapon CI-65 is used in hand sanitizers and antibacterial hand washes for effective cleansing and disinfection.
Jordapon CI-65 is added to exfoliating body washes and scrubs, promoting smoother and more radiant skin.
Jordapon CI-65 is utilized in cream and gel-based deodorants, providing gentle cleansing while neutralizing odor.

Jordapon CI-65 is incorporated into intimate lubricants and washes, helping to maintain comfort and hygiene in sensitive areas.
Jordapon CI-65 is found in cuticle creams and nail treatments, moisturizing and nourishing the nails and cuticles.
Jordapon CI-65 is utilized in foot care products such as foot masks and soaks, softening rough skin and relieving dryness.

Jordapon CI-65 is added to bath oils and bath salts, enhancing the relaxation and therapeutic benefits of a warm bath.
Jordapon CI-65 is incorporated into hand creams and lotions, providing long-lasting hydration and protection.
Jordapon CI-65 is found in anti-dandruff shampoos and scalp treatments, helping to soothe irritation and control flakiness.

Jordapon CI-65 is used in body butter and moisturizing creams, providing intense hydration for dry and rough skin.
Jordapon CI-65 is incorporated into lip care products such as lip balms and treatments, helping to repair and nourish chapped lips.
Jordapon CI-65 is utilized in hair masks and deep conditioning treatments, restoring moisture and shine to dry and damaged hair.

Jordapon CI-65 is added to sun care products such as after-sun lotions, providing soothing and moisturizing benefits to sun-exposed skin.
Jordapon CI-65 is found in natural soap formulations, offering gentle cleansing without harsh chemicals or sulfates.
Jordapon CI-65 is utilized in facial exfoliating pads and wipes, providing convenient and effective cleansing on the go.

Jordapon CI-65 is added to bath milk and bath soak formulations, creating a luxurious and indulgent bathing experience.
Jordapon CI-65 is incorporated into hair styling products such as pomades and waxes, providing texture and hold.
Jordapon CI-65 is found in body powder formulations, offering moisture absorption and skin-soothing properties.

Jordapon CI-65 is utilized in anti-cellulite creams and treatments, promoting smoother and firmer-looking skin.
Jordapon CI-65 is added to hand soaps and foaming hand washes, providing effective cleansing with a luxurious lather.
Jordapon CI-65 is found in natural toothpaste formulations, helping to clean and refresh the mouth without harsh chemicals.
Jordapon CI-65 is incorporated into facial essence and essence toners, providing hydration and preparing the skin for subsequent skincare steps.



DESCRIPTION


Jordapon CI-65 is a versatile surfactant blend used in personal care formulations.
Jordapon CI-65 combines Sodium Cocoyl Isethionate and Stearic Acid to create a synergistic effect.
With its creamy texture and mild cleansing properties, Jordapon CI-65 is ideal for gentle skincare products.

Jordapon CI-65 offers excellent foaming capabilities, producing rich lather in cleansing formulations.
Jordapon CI-65 is derived from natural, renewable sources, making it environmentally friendly.
Its low-dusting nature and easy handling characteristics make it suitable for manufacturing processes.

Jordapon CI-65 imparts a soft and smooth after-feel, leaving the skin feeling refreshed and moisturized.
Jordapon CI-65 exhibits mildness, making it suitable for sensitive skin types, including babies and those with dermatological conditions.
Jordapon CI-65 is free from harsh chemicals and sulfates, making it a preferred choice for natural and clean beauty formulations.

Jordapon CI-65 offers biodegradability, ensuring minimal environmental impact upon disposal.
Jordapon CI-65 is compatible with a wide range of cosmetic ingredients, allowing for versatile formulations.
Its stable composition and compatibility with other additives contribute to the overall efficacy of cosmetic products.

In facial cleansers and body washes, Jordapon CI-65 provides thorough yet gentle cleansing without stripping the skin of its natural oils.
Jordapon CI-65 enhances the sensory experience of personal care products, offering a luxurious feel during use.
Jordapon CI-65 contributes to the creamy texture and smooth consistency of creams, lotions, and gels.
In syndet bars and combo bars, the blend creates a dense, long-lasting lather for effective cleansing.

Jordapon CI-65 is commonly used in aerosol shave creams to provide a smooth and comfortable shaving experience.
Jordapon CI-65 is suitable for a variety of hair care products, including shampoos and conditioners, for its cleansing and conditioning properties.
Its versatility extends to bath products such as bath bombs and bubble baths, adding frothy bubbles to the bathwater.

Jordapon CI-65 is often used in natural and organic formulations, aligning with consumers' preferences for clean beauty.
Jordapon CI-65 contributes to the overall stability and shelf life of cosmetic formulations.
Its non-comedogenic nature makes it suitable for facial cleansers and acne treatment products.

Jordapon CI-65's gentle cleansing action makes it suitable for daily use in personal care routines.
Jordapon CI-65 undergoes rigorous quality control measures to ensure consistency and performance in cosmetic applications.
Overall, Jordapon CI-65 is a reliable and versatile ingredient that enhances the efficacy and sensory appeal of personal care products.



PROPERTIES


Chemical Composition: Blend of Sodium Cocoyl Isethionate and Stearic Acid.
Physical Form: Solid (typically in powder or granular form).
Appearance: White to off-white solid.
Odor: Mild, characteristic odor.
Solubility: Soluble in water.
pH (1% aqueous solution): Typically around pH 5-7.
Melting Point: Varies depending on the specific composition and ratio of components.
Boiling Point: Decomposes before boiling.
Density: Varies depending on the specific composition and ratio of components.
Hygroscopicity: May absorb moisture from the air.
Stability: Stable under normal storage and handling conditions.



FIRST AID


Inhalation:

If inhaled, remove the affected person to an area with fresh air.
Allow the individual to rest in a comfortable position and monitor their breathing.
If breathing difficulties persist or if the person becomes unconscious, seek medical attention immediately.
Provide artificial respiration if the person is not breathing and is trained to do so.


Skin Contact:

Remove contaminated clothing and rinse the affected area thoroughly with water for at least 15 minutes.
Use mild soap if available to cleanse the skin gently.
If irritation or redness develops, seek medical attention.
Apply a moisturizing cream or lotion to soothe any discomfort.


Eye Contact:

Immediately flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses, if present and easily removable, after the initial flushing, and continue rinsing.
Seek immediate medical attention if irritation, redness, or other symptoms persist after rinsing.


Ingestion:

If swallowed, rinse the mouth thoroughly with water.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek medical attention immediately.
Provide supportive care as directed by medical professionals.



HANDLING AND STORAGE


Handling Precautions:

When handling Jordapon CI-65, wear appropriate personal protective equipment (PPE) such as safety goggles, gloves, and protective clothing to minimize the risk of skin and eye contact.
Avoid inhalation of dust or aerosols by working in a well-ventilated area or using local exhaust ventilation systems.
Do not eat, drink, or smoke while handling Jordapon CI-65 to prevent accidental ingestion.
Wash hands thoroughly with soap and water after handling Jordapon CI-65 and before eating, drinking, or using the restroom.
Keep Jordapon CI-65 containers tightly closed when not in use to prevent contamination and moisture absorption.
Use suitable tools and equipment, such as scoops or spatulas, to handle Jordapon CI-65 and minimize dust generation.
Clean up spills promptly using suitable absorbent materials and dispose of them in accordance with local regulations.
Store Jordapon CI-65 away from incompatible materials such as strong acids, oxidizing agents, and alkalis to prevent hazardous reactions.
Avoid contact with skin, eyes, and clothing. In case of contact, follow appropriate first aid measures.


Storage Conditions:

Store Jordapon CI-65 in a cool, dry, and well-ventilated area away from direct sunlight and heat sources.
Keep containers tightly closed and upright to prevent spills and leakage.
Store Jordapon CI-65 away from sources of ignition and open flames to reduce the risk of fire.
Maintain proper labeling on Jordapon CI-65 containers, including product name, composition, and hazard warnings.
Store Jordapon CI-65 separately from food, beverages, and animal feed to prevent contamination.
Inspect Jordapon CI-65 containers regularly for signs of damage, leakage, or deterioration, and replace them if necessary.
Store Jordapon CI-65 containers on shelves or pallets to prevent direct contact with the floor and facilitate inspection and handling.
Keep Jordapon CI-65 containers in a secure area accessible only to authorized personnel to prevent unauthorized access or tampering.
Follow any specific storage instructions provided by the manufacturer or supplier, including temperature and humidity requirements.
Ensure that storage areas are equipped with appropriate firefighting equipment and spill containment measures in case of emergencies.


Transportation Precautions:

When transporting Jordapon CI-65, use suitable containers that are compatible with the chemical and securely sealed to prevent leaks or spills.
Ensure that Jordapon CI-65 containers are properly labeled with product information and hazard warnings.
Follow applicable regulations and guidelines for the transportation of hazardous chemicals, including packaging, labeling, and documentation requirements.
Take precautions to prevent damage to Jordapon CI-65 containers during loading, unloading, and transportation.
In case of spills or leaks during transportation, follow established procedures for containment, cleanup, and disposal.
Provide training to personnel involved in the transportation of Jordapon CI-65 to ensure safe handling practices and emergency response procedures.
JORDAPON SCI

Jordapon SCI is a mild and gentle surfactant commonly used in personal care products.
Jordapon SCI is derived from coconut oil and is known for its excellent cleansing properties.
Jordapon SCI is available in powder or granular form, making it easy to incorporate into various formulations.

CAS Number: 61789-32-0
EC Number: 263-052-5

SCI, Sodium coco sulfate, Sodium cocoyl isethionate, Sodium N-cocoyl-N-methyltaurate, Sodium isethionate, Sodium cocoyl glycinate, Sodium cocoyl methyl taurate, Sodium cocoyl sarcosinate, Sodium cocoyl glutamate, Sodium cocoyl alaninate, Sodium N-lauroyl-N-methyltaurate, Sodium N-cocoyl-N-methylglycinate, Sodium lauroyl sarcosinate, Sodium cocoyl hydrolyzed wheat protein, Sodium cocoyl collagen amino acids, Sodium cocoyl silk amino acids, Sodium cocoyl oat amino acids, Sodium lauroyl oat amino acids, Sodium lauroyl hydrolyzed collagen, Sodium cocoyl hydrolyzed collagen, Sodium cocoyl hydrolyzed keratin, Sodium lauroyl hydrolyzed keratin, Sodium cocoyl hydrolyzed silk, Sodium lauroyl hydrolyzed silk, Sodium lauroyl hydrolyzed oat protein, Sodium cocoyl hydrolyzed oat protein, Sodium lauroyl hydrolyzed soy protein, Sodium cocoyl hydrolyzed soy protein, Sodium lauroyl hydrolyzed wheat protein, Sodium cocoyl hydrolyzed wheat protein, Sodium lauroyl hydrolyzed rice protein, Sodium cocoyl hydrolyzed rice protein, Sodium lauroyl hydrolyzed quinoa, Sodium cocoyl hydrolyzed quinoa, Sodium lauroyl hydrolyzed amaranth, Sodium cocoyl hydrolyzed amaranth, Sodium lauroyl hydrolyzed millet, Sodium cocoyl hydrolyzed millet, Sodium lauroyl hydrolyzed barley, Sodium cocoyl hydrolyzed barley, Sodium lauroyl hydrolyzed corn protein, Sodium cocoyl hydrolyzed corn protein, Sodium lauroyl hydrolyzed pea protein, Sodium cocoyl hydrolyzed pea protein, Sodium lauroyl hydrolyzed soybean protein, Sodium cocoyl hydrolyzed soybean protein, Sodium lauroyl hydrolyzed sunflower seed protein, Sodium cocoyl hydrolyzed sunflower seed protein, Sodium lauroyl hydrolyzed vegetable protein, Sodium cocoyl hydrolyzed vegetable protein, Sodium lauroyl hydrolyzed lupine protein, Sodium cocoyl hydrolyzed lupine protein, Sodium lauroyl hydrolyzed pumpkin seed protein, Sodium cocoyl hydrolyzed pumpkin seed protein, Sodium lauroyl hydrolyzed sesame seed protein, Sodium cocoyl hydrolyzed sesame seed protein, Sodium lauroyl hydrolyzed almond protein, Sodium cocoyl hydrolyzed almond protein



APPLICATIONS


Jordapon SCI is commonly used in shampoo formulations for its excellent cleansing properties.
Jordapon SCI is employed in body washes and shower gels to create a rich and creamy lather that effectively cleanses the skin.
Jordapon SCI is a key ingredient in facial cleansers and cleanser bars due to its gentle yet effective cleansing action.

Jordapon SCI is used in baby care products such as gentle cleansers and bubble baths for its mildness.
Jordapon SCI is utilized in hand soaps and liquid hand washes to provide thorough cleansing without drying out the skin.

Jordapon SCI is incorporated into sulfate-free and natural hair care products as a gentle alternative to traditional surfactants.
Jordapon SCI is found in shaving creams and foams to provide lubrication and help soften facial hair for a smooth shave.

Jordapon SCI is used in bath bombs and bath salts to create foaming and bubbling effects in the bathwater.
Jordapon SCI is added to facial scrubs and exfoliating cleansers to help remove dead skin cells and unclog pores.

Jordapon SCI is utilized in toothpaste formulations to create foam and assist in the removal of plaque and debris from the teeth.
Jordapon SCI is incorporated into liquid and bar soap formulations for its ability to produce stable and long-lasting lather.

Jordapon SCI is used in pet grooming products such as shampoos and conditioners for its gentle cleansing properties.
Jordapon SCI is employed in intimate hygiene products such as feminine washes and wipes to maintain freshness and cleanliness.

Jordapon SCI is found in facial masks and cleanser pads for its ability to deliver cleansing and exfoliating benefits.
Jordapon SCI is used in pre-shave and post-shave products to help prepare the skin for shaving and soothe irritation afterward.
Jordapon SCI is added to bath oils and bath melts to help disperse essential oils and moisturizing ingredients in the bathwater.
Jordapon SCI is utilized in sunscreen formulations as an emulsifier and surfactant to improve spreadability and water resistance.

Jordapon SCI is found in hair styling products such as mousses and foams to provide hold and volume without weighing down the hair.
Jordapon SCI is employed in facial cleanser wipes and makeup remover wipes for convenient and effective cleansing on the go.

Jordapon SCI is used in foot care products such as foot scrubs and foot soaks to help soften calluses and remove dead skin.
Jordapon SCI is found in acne treatment products such as cleansers and spot treatments for its gentle yet effective cleansing action.

Jordapon SCI is utilized in deodorant formulations as a mild surfactant to help disperse active ingredients and provide cleansing benefits.
Jordapon SCI is incorporated into bath bombs and shower steamers to create a foaming and aromatic experience in the shower or bath.
Jordapon SCI is used in scalp treatments and dandruff shampoos for its cleansing and soothing properties on the scalp.
Jordapon SCI is found in natural and organic personal care products as a preferred alternative to harsher surfactants due to its mildness and biodegradability.

Jordapon SCI is utilized in facial cleanser formulations to provide a gentle yet thorough cleansing experience for sensitive skin types.
Jordapon SCI is incorporated into makeup remover products such as cleansing balms and oils to effectively dissolve and remove makeup.
Jordapon SCI is added to bath foams and bubble baths to create luxurious and long-lasting bubbles for a relaxing bathing experience.

Jordapon SCI is found in body scrubs and exfoliating treatments to help slough off dead skin cells and reveal smoother skin.
Jordapon SCI is used in hair masks and deep conditioning treatments to help improve the manageability and softness of the hair.

Jordapon SCI is added to hair coloring products such as shampoos and conditioners to help maintain color vibrancy and prolong color retention.
Jordapon SCI is employed in hair volumizing products such as mousses and foams to provide lift and body to fine or limp hair.
Jordapon SCI is found in dry shampoo formulations to help absorb excess oil and refresh the hair between washes.

Jordapon SCI is utilized in intimate hygiene products such as feminine washes and wipes to maintain pH balance and freshness.
Jordapon SCI is incorporated into hand sanitizers and antibacterial hand washes for its cleansing and disinfecting properties.
Jordapon SCI is added to facial toners and astringents to help remove excess oil and impurities from the skin's surface.

Jordapon SCI is found in anti-aging skincare products such as serums and creams to help improve skin texture and reduce the appearance of fine lines.
Jordapon SCI is used in foot scrubs and foot soaks to help soften rough skin and soothe tired feet.

Jordapon SCI is employed in cuticle creams and nail treatments to help moisturize and nourish the nails and cuticles.
Jordapon SCI is added to bath salts and bath teas to help enhance the relaxation and therapeutic benefits of a warm bath.

Jordapon SCI is found in body lotions and moisturizers to help improve skin hydration and prevent moisture loss.
Jordapon SCI is utilized in lip scrubs and lip balms to help exfoliate and hydrate the lips for a smoother, softer appearance.

Jordapon SCI is incorporated into massage oils and body oils to help facilitate glide and absorption into the skin.
Jordapon SCI is added to sunless tanning products such as mousses and lotions to help distribute the tanning agent evenly across the skin.

Jordapon SCI is found in acne spot treatments and blemish control products for its cleansing and soothing properties.
Jordapon SCI is used in natural and organic personal care products such as bar soaps and solid shampoos for its mildness and biodegradability.

Jordapon SCI is employed in bath bombs and bath fizzies to help create effervescent and aromatic baths.
Jordapon SCI is added to pet grooming products such as shampoos and conditioners for its gentle cleansing and conditioning properties.

Jordapon SCI is found in facial mists and sprays to help hydrate and refresh the skin throughout the day.
Jordapon SCI is utilized in wound care products such as cleansing wipes and antiseptic solutions for its gentle yet effective cleansing action on the skin.



DESCRIPTION


Jordapon SCI is a mild and gentle surfactant commonly used in personal care products.
Jordapon SCI is derived from coconut oil and is known for its excellent cleansing properties.
Jordapon SCI is available in powder or granular form, making it easy to incorporate into various formulations.

Jordapon SCI produces rich, creamy lather that effectively removes dirt, oil, and impurities from the skin and hair.
Jordapon SCI is often used in shampoos, body washes, facial cleansers, and baby care products due to its mildness.

Jordapon SCI is suitable for all skin types, including sensitive and delicate skin, as it does not cause irritation or dryness.
Jordapon SCI helps to soften and condition the skin, leaving it feeling smooth and moisturized after use.
In hair care products, Jordapon SCI helps to cleanse the scalp and hair without stripping away natural oils or causing damage.

Jordapon SCI is often found in sulfate-free and gentle cleansing formulas designed to maintain the natural balance of the skin and hair.
Jordapon SCI is biodegradable and environmentally friendly, making it a preferred choice for eco-conJordapon SCIous consumers.

Jordapon SCI has excellent foaming properties, contributing to luxurious lather in personal care products.
Jordapon SCI is compatible with other surfactants and cosmetic ingredients, allowing for versatile formulations.

Jordapon SCI helps to stabilize emulsions and improve the overall texture and feel of cosmetic products.
Jordapon SCI is pH-balanced and does not disrupt the skin's natural acid mantle, making it suitable for daily use.

Jordapon SCI is non-comedogenic and does not clog pores, making it suitable for use in facial cleansers and acne treatments.
Jordapon SCI is considered safe for use in cosmetics and personal care products when used as directed.

Jordapon SCI is often used in combination with other surfactants to enhance performance and sensory attributes.
Jordapon SCI is free from harsh chemicals such as sulfates, parabens, and phthalates, making it a preferred choice for natural and clean beauty formulations.

Jordapon SCI is produced using sustainable and environmentally friendly manufacturing processes.
Jordapon SCI has a neutral odor and does not impart fragrance to cosmetic products, making it suitable for fragrance-sensitive individuals.

Jordapon SCI is readily biodegradable and does not accumulate in the environment, minimizing its ecological impact.
Jordapon SCI is gentle enough for use in baby care products such as gentle cleansers and diaper creams.

Jordapon SCI is often used in facial cleansers and exfoliating scrubs to provide gentle yet effective cleansing and exfoliation.
Jordapon SCI is water-soluble and rinses off easily without leaving a residue on the skin or hair.
Jordapon SCI is a versatile and effective surfactant that offers gentle cleansing and conditioning benefits for the skin and hair.



PROPERTIES


Chemical Formula: C₂₈H₅₅NO₇S
Molecular Weight: Approximately 573.81 g/mol
Physical Form: Solid (typically in powder or granular form)
Appearance: White to off-white solid
Odor: Mild, characteristic odor
Solubility: Soluble in water
pH (1% aqueous solution): Typically around pH 5-7
Melting Point: Varies depending on the specific grade, typically around 150-180°C
Boiling Point: Decomposes before boiling
Density: Varies depending on the specific grade
Hygroscopicity: Hygroscopic (absorbs moisture from the air)
Stability: Stable under normal storage and handling conditions
Compatibility: Compatible with a wide range of cosmetic ingredients and additives
Foaming Properties: Produces rich, creamy lather in water
Cleansing Ability: Effectively removes dirt, oil, and impurities from the skin and hair
Emulsifying Ability: Acts as an emulsifier, helping to stabilize oil-in-water emulsions
Mildness: Gentle on the skin and hair, suitable for sensitive skin types
Biodegradability: Readily biodegradable under aerobic conditions
Environmental Impact: Low environmental toxicity and minimal environmental impact when used as directed



FIRST AID


Inhalation:

If inhaled, move the affected person to an area with fresh air.
Allow the person to rest in a comfortable position and keep them warm.
If breathing difficulties persist, seek medical attention immediately.
Provide artificial respiration if the person is not breathing and trained to do so.


Skin Contact:

Remove contaminated clothing and rinse the affected area with plenty of water for at least 15 minutes.
If irritation or redness occurs, seek medical attention.
Wash contaminated skin thoroughly with soap and water.
Apply a mild moisturizer or emollient to soothe any discomfort.


Eye Contact:

Immediately flush the eyes with gently flowing water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Remove contact lenses, if present and easily removable, after the initial flushing, and continue rinsing.
Seek immediate medical attention if irritation, redness, or other symptoms persist after rinsing.


Ingestion:

If swallowed, rinse the mouth thoroughly with water.
Do not induce vomiting unless instructed by medical personnel.
Seek medical attention immediately.
Provide supportive care as directed by medical professionals.


First Aid for First Responders:

Wear appropriate personal protective equipment (PPE), including gloves, goggles, and protective clothing, when providing first aid.
Avoid direct contact with the chemical to prevent secondary exposure.
Follow standard first aid procedures and protocols for chemical exposures.
If unsure about the appropriate course of action, contact poison control or seek guidance from a healthcare professional.



HANDLING AND STORAGE


Handling Precautions:

When handling Jordapon SCI, wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and protective clothing, to minimize the risk of skin and eye contact.
Avoid inhalation of dust or aerosols by working in a well-ventilated area or using local exhaust ventilation systems.

Do not eat, drink, or smoke while handling Jordapon SCI to prevent accidental ingestion.
Wash hands thoroughly with soap and water after handling Jordapon SCI and before eating, drinking, or using the restroom.
Keep Jordapon SCI containers tightly closed when not in use to prevent contamination and moisture absorption.

Avoid contact with incompatible materials, such as strong acids, oxidizing agents, and alkalis, to prevent hazardous reactions.
Use appropriate tools and equipment, such as scoops or spatulas, to handle Jordapon SCI and minimize dust generation.
Clean up spills promptly using suitable absorbent materials and dispose of them in accordance with local regulations.


Storage Conditions:

Store Jordapon SCI in a cool, dry, well-ventilated area away from sources of heat and ignition.
Keep containers tightly closed and upright to prevent spills and leakage.
Store Jordapon SCI away from direct sunlight and moisture to prevent degradation and caking.
Maintain proper labeling on Jordapon SCI containers, including product name, chemical composition, and hazard warnings.

Store Jordapon SCI separately from incompatible materials, such as acids, oxidizing agents, and alkalis, to prevent hazardous reactions.
Do not store Jordapon SCI near food, beverages, or animal feed to avoid contamination.
Store Jordapon SCI containers on shelves or pallets to prevent direct contact with the floor and facilitate inspection and handling.

Check Jordapon SCI containers regularly for signs of damage, leakage, or deterioration, and replace them if necessary.
Follow any specific storage instructions provided by the manufacturer or supplier, including temperature and humidity requirements.
Keep Jordapon SCI containers in a secure area accessible only to authorized personnel to prevent unauthorized access or tampering.


Transportation Precautions:

When transporting Jordapon SCI, use appropriate containers that are compatible with the chemical and securely sealed to prevent leaks or spills.
Ensure that Jordapon SCI containers are properly labeled with the product name, hazard warnings, and handling instructions.

Follow applicable regulations and guidelines for the transportation of hazardous chemicals, including packaging, labeling, and documentation requirements.
Take precautions to prevent damage to Jordapon SCI containers during loading, unloading, and transportation.

In case of spills or leaks during transportation, follow established procedures for containment, cleanup, and disposal.
Provide training to personnel involved in the transportation of Jordapon SCI to ensure safe handling practices and emergency response procedures.


Emergency Procedures:

In the event of a spill, leak, or accidental release of Jordapon SCI, follow established emergency procedures for chemical spills and hazardous material incidents.
Evacuate the area if necessary to prevent exposure to chemical vapors or dust.
Notify appropriate personnel, such as safety officers, supervisors, or emergency responders, of the incident.

Provide information about the chemical involved, including its identity, quantity, and location.
Use appropriate containment measures, absorbent materials, and personal protective equipment to safely clean up spills.
Dispose of contaminated materials and waste in accordance with local regulations and guidelines.

Report the incident to appropriate authorities, such as workplace safety officials or poison control centers, if necessary.
Provide follow-up care and monitoring for individuals involved in the incident to ensure their health and safety.
JORDAPON SCI
Jordapon SCI is an anionic surfactant and a good foamer.
Jordapon SCI offers benefits including soft after feel, mildness and biodegradability.
Jordapon SCI is based upon fatty acids from natural, renewable coconut oil.


CAS Number: 61789-32-0 / 58969-27-0
EC Number: 263-052-5
INCI NAME: Sodium Cocoyl Isethionate.
Chem/IUPAC Name:Fatty acids, coco, 2-sulfoethyl esters, sodium salts
MDL Number: MFCD01772282
Molecular formula: C6H11NaO5S


Jordapon SCI Powder is a very highly active, finely divided, free-flowing powder (sodium cocoyl isethionate) used in syndet bars, combo bars, liquid soaps, facial cleansers, body washes and shampoos.
Jordapon SCI has high foaming power, extreme mildness, and a soft and silky skin feel.


Jordapon SCI foams excellently in even hard water, convinces with its mild scent and is also called baby foam because of its gentleness.
Jordapon SCI is an anionic co-surfactant ideally suited for mild personal care cleansing products, such as shampoo, body wash, liquid soap and syndet bar.


Jordapon SCI is a Solid.
Jordapon SCI is a very high activity, solid Sodium Cocoyl Isethionate that is used in syndet bars, combo bars, liquid soaps, adnfacial cleansers.


Jordapon SCI is a very high activity, solid Sodium Cocoyl Isethionate that is used in syndet bars, combo bars, liquid soaps, facial cleansers, body cleansers and shampoos.
Jordapon SCI has high foaming performance, extreme mildness, as well as soft and silky skin after feel characteristics.


Jordapon SCI is an anionic surfactant and a good foamer.
Jordapon SCI offers benefits including soft after feel, mildness and biodegradability.
Jordapon SCI is based upon fatty acids from natural, renewable coconut oil.


Jordapon SCI is an anionic co-surfactant ideally suited for mild personal care cleansing products, such as shampoo, body wash, liquid soap and syndet bar.
Jordapon SCI is an easy to handle, coconut derived, anionic, mild primary surfactant which creates a product with a dense and luxurious foam.


Jordapon SCI can be used alone to make a cream or solid cleansing bar, or combined with other surfactants to make a creamy shampoo or body wash.
Jordapon SCI creates an elegant feel during use and a conditioned after feel in both hair and skincare formulations.
Jordapon SCI is a sodium salt of the fatty acid, isethionic acid.


Jordapon SCI is a very high activity, solid Sodium Cocoyl Isethionate that is used in syndet bars, combo bars, liquid soaps, facial cleansers, body cleansers, and shampoos.
Jordapon SCI has high foaming performance, extreme mildness, as well as soft and silky skin after feel characteristics.


Jordapon SCI is mild to skin and eyes.
Jordapon SCI is an excellent foamers in hard or soft water.
Jordapon SCI is impart a soft after-feel to skin.


Jordapon SCI has mild odor.
Jordapon SCI is based upon fatty acids from natural, renewable coconut oil.
Jordapon SCI is completely biodegradable.


Jordapon SCI is a very high-activity, solid sodium cocoyl isethionate.
Jordapon SCI is a white flakes.
Jordapon SCI is an anionic surfactant obtained from coconut oil


Jordapon SCI is a light surfactant, gentle on the eyes and skin and friendly to the environment since it is based on purified fatty acids derived from coconut oil, which is a natural, renewable and biodegradable resource .
If you are making a liquid product with Jordapon SCI, it will need to be dissolved in a suitable solvent first.


Jordapon SCI does not dissolve readily into water; I once combined some Jordapon SCI with water in a jar, sealed it, and left it for 6 months.
Jordapon SCI never dissolved.
I recommend combining Jordapon SCI with the liquid amphoteric surfactant that is likely also present in the recipe and heating the two together in a water bath until you have a uniform paste.


That paste will dissolve into water.
If you are working with a large amount of this Jordapon SCI + amphoteric surfactant blend you can speed things along by using an immersion blender to get the mixture silky smooth—the low water content means it won’t lather up, but you’ll get a smooth paste very quickly!


You can also speed up the process by running your Jordapon SCI through a coffee grinder before combining it with the liquid amphoteric surfactant—just be sure you are wearing your dust mask!
Hydrous formulations including Jordapon SCI should have a pH of 6–8 or the Jordapon SCI can hydrolyze.


That said, I have made more acidic formulations featuring Jordapon SCI and haven’t had troubles—though those batches would’ve been quite small and the products were finished quickly.
Jordapon SCI is a surfactant based on fatty acids from coconut oil and isoethionic acid, a type of sulfonic acid.


Commonly known as Baby Foam due to its exceptional mildness, Jordapon SCI is a surfactant that is comprised of a type of sulphonic acid called Isethionic Acid as well as the fatty acid – or sodium salt ester – obtained from Coconut Oil.
Jordapon SCI is a traditional substitute for sodium salts that are derived from animals, namely sheep and cattle.


Jordapon SCI is a solid, gentle anionic surfactant made from coconut oil.
Jordapon SCI is really versatile and lovely, and is considered natural.
Jordapon SCI is a powdered surfactant made from renewable coconut fatty acids that is fully biodegradable.


Jordapon SCI is one of the gentlest surfactants on the market leading it to also being known as Baby Foam, as this surfactant is mild enough to be used in baby products and personal cleansers like eye makeup remover.
Jordapon SCI is made from the renewable fatty acid, or sodium salt ester, that is obtained from Coconut Oil.


Jordapon SCI is a common replacement for animal-derived sodium salts such as Sodium Tallowate.
Jordapon SCI is a biodegradable, powdered surfactant that allows it to easily be added to formulations.
Jordapon SCI is one of the gentlest and mildest surfactants on the market, leading it to acquire the moniker of Baby Foam due to its use in various baby products.


Jordapon SCI is an anionic surfactants of vegetable and synthetic origins from fatty acids of coconut oil (derived from fatty acids of coconut oil) and isethionic acid.
Solid, Jordapon SCI is in the form of white granules or powder.


Once integrated into a formula, Jordapon SCI is soft for the eyes and biodegradable.
Jordapon SCI is soluble in water, and insoluble in oil.
Jordapon SCI is soft, very foaming cleaner.


Jordapon SCI leaves the skin and the hair soft.
Jordapon SCI is liquid and solid shampoos.
In the dry state, Jordapon SCI is very irritating for the respiratory tract.


Jordapon SCI is mild, high foaming, sulfate-free anionic surfactant combined with disodium cocoyl glutamate, a gentle cleanser produced from natural sources including coconut fatty acids and fermented sugar.
Jordapon SCI is mild anionic surfactant.


Jordapon SCI has high foaming performance, extreme softness, as well as silky smooth skin characteristics after touch.
Jordapon SCI is Gentle on skin and eyes.
Jordapon SCI is ideal for baby care and gentle cleaning products.


Jordapon SCI is made from natural coconut oil and is completely biodegradable.
Jordapon SCI is recommended for systems where a low percentage of fatty acids is needed, e.g. shampoos, bath and shower gels and liquid soaps.
Jordapon SCI is soluble in some water.


Jordapon SCI is a naturally-derived ingredient that comes from the fatty acids that are present in isethionic acid and coconut oil.
Jordapon SCI is also soluble in surfactants (some formulations may require some heat)
No ethoxylation takes place in the manufacture of Jordapon SCI.


Jordapon SCI is an ester of long-chain aliphatic carboxylic acids ( fatty acids ) obtained from coconut oil with isethionic acid or sodium isethionate and belongs to the class of isethionates, which are also referred to in the literature as acyl isethionates or, according to chemical nomenclature, as 2-sulfoethylcarboxylic acid esters or acyloxyethanesulfonates.


The most important representative of this class of mild anionic surfactants is Jordapon SCI, which is referred to in the English literature as Jordapon SCI.
Jordapon SCI is a mild, high foaming anionic surfactant with high purity made from coconut fatty acids.


Jordapon SCI has minimum 85% active matter.
Jordapon SCI has free fatty acid 14% maximum.
Jordapon SCI has excellent foam density and foam stability.


Jordapon SCI has very good lime soap dispersion and surface activity. Leaves no soap scum as it is very hard water tolerant.
Jordapon SCI is compatible with soaps and anionic, non-ionic, and amphoteric surfactant.
Jordapon SCI is excellent lathering; exceptionally mild, provides soft skin after-feel.



These fatty acids are reacted with sodium isethionate and the mixture is heated to remove any water left behind.
Further, the mixture is distilled to remove excess fatty acids.
In its raw form, Jordapon SCI appears as a fine white powder.


Jordapon SCI is a naturally-derived ingredient that comes from the fatty acids that are present in isethionic acid and coconut oil.
These fatty acids are reacted with sodium isethionate and the mixture is heated to remove any water left behind.
Further, the mixture is distilled to remove excess fatty acids.


Jordapon SCI is a gentle surfactant derived from coconut oil that is commonly used in skincare and haircare products.
This white, powdery substance, Jordapon SCI, has gained popularity due to its mild, non-irritating nature, making it suitable for a variety of personal care applications.


Jordapon SCI is a sodium salt of the coconut fatty acid ester of isethionic acid.
Jordapon SCI is an anionic surfactant, meaning it carries a negative charge that helps to create a lather and lift dirt, oil, and impurities from the skin and hair.


A cleansing agent, Jordapon SCI is claimed to be so gentle on the skin that it hardly impacts the skin barrier.
Jordapon SCI also gives a rich, creamy foam, it's based on vegetable fatty acids and is readily biodegradable.
Jordapon SCI's an especially important and popular ingredient in "syndet bars" (or soapless soaps).


Jordapon SCI provides skincare benefits and serves as a fantastic alternative to harsher, drying cleansers (like sulfates).
Jordapon SCI is a natural surfactant derived from Vegetable Oils.
Jordapon SCI has high foaming performance, extreme mildness, as well as soft and silky skin after feel characteristics.


Jordapon SCI in powder form is much easier to incorporate into your products compared to noodles or granular alternatives.
Jordapon SCI is a surfactant made up of Isethionic Acid, a form of sulphonic acid, and the fatty acid – or sodium salt ester – produced from Coconut Oil.


Jordapon SCI’s commonly referred to as Baby Foam because of its outstanding mildness.
Jordapon SCI is an anionic surfactant, i.e. an amphophilic compound.
These compounds dissociate and are biodegradable.


Their most frequent application is in cosmetic products.
Jordapon SCI is an ingredient derived from coconut oil.
Jordapon SCI is a fine white Powder and far superior to the SCI granules, flakes or needles currently available on the market.


Jordapon SCI is naturally derived and biodegradeable while being suitable for Vegans.
Jordapon SCI is a mild surfactant (cleansing agent) derived from isethionic acid and coconut fatty acids.
In its raw state, Jordapon SCI usually appears as white granular solids.


Jordapon SCI can be used in personal care products as a gentle surfactant, helping to mix water with oil and dirt so they can be washed away, without stripping the skin's natural barrier.
Like many coconut-derived cleansers, Jordapon SCI also contributes to lather, producing a luxurious creamy foam that does not dry out skin.


Jordapon SCI is a mild soap-free cleansing agent known for its ability to mitigate disruption of skin’s barrier.
Jordapon SCI is derived from coconut and is regarded as compatible with sensitive skin.
Jordapon SCI’s an anionic surfactant, meaning a cleansing agent with a negative instead of a positive charge.


Anionic surfactants are the most common type due to their ability to lift and suspend dirt, oil, and debris, allowing them to be washed away.
Suppliers of Jordapon SCI tout its gentle foaming action as a desirable quality for consumers, even though the foam itself has little cleansing ability.


In addition to skin care formulations, Jordapon SCI is a popular ingredient in hair products.
Jordapon SCI is a powder in its raw material form.
Jordapon SCI is a natural ingredient that is derived from coconuts, specifically coconut oil and isethionic acid.


Jordapon SCI exhibits high foaming ability, producing a stable, rich and velvety lather, without damaging the moisture barrier or taking stripping away hydration.



USES and APPLICATIONS of JORDAPON SCI:
Personal Care uses of Jordapon SCI; Beauty & Care, Baby Care, Bath & Shower, Hair Care, and Skin Care.
HI&I Care uses of Jordapon SCI;Home Care and Pet Care
Bath & Shower Applications of Jordapon SCI: Bar Soaps, Body Wash, and Liquid Soap.


Hair Care Applicationso of Jordapon SCI: Hair Conditioner, and Shampoos & Rinses.
Skin Care Applications of Jordapon SCI: Facial Cleanser, and Skin Cleanser.
Jordapon SCI is our favourite surfactant - it's just so giving!


Jordapon SCI provides loads of lather, and can be used to make liquid and solid bar cleansers and shampoos.
Jordapon SCI is used Bath & Shower, Body Care, Hand Cleansing, Skin Cleansing
Jordapon SCI can be used in Syndet (synthetic detergent) bars, Combobars (mixtures of synthetic and soap), Liquid soaps, Facial cleansers, and Body cleansers and shampoos.


Jordapon SCI is used in personal cleansing products like syndet bar, combo bars, foaming facial washes, body washes, shampoos, bath and showers gels and liquid soaps.
Jordapon SCI is used Anionic co-surfactant ideally suited for mild personal care cleansing products, such as shampoo, body wash, liquid soap and syndet bar.


Applications of Jordapon SCI: Bath & Shower, Body Care, Hair Cleansing, Hand Cleansing, Liquid Soap, Skin Care, Skin Cleansing
Jordapon SCI is used Baby Care and Cleansing, Face Cleansing, Liquid Soap, Shampoo, Shower/Bath Products
Jordapon SCI is a detergent that blends well with skin and hair.


Therefore, Jordapon SCI can be used as a coagulant in cleaning formulas such as facial cleansing gel/cream, facial cleansing powder, shampoo, liquid soap, shower cream.
Jordapon SCI is commonly used in formulas that are gentle (mildness).


Jordapon SCI is also used in the production of soap bars (Syndet bar).
Jordapon SCI is used Gentle, high foaming personal cleansing products, Bar toilet soaps, Pearlescent liquid soaps, Foams for facial wash, Body shampoos, Hair shampoos, and Sulfate-free shampoos.


Jordapon SCI is a natural anionic surfactant which allows the implementation of solid foaming agents, but also without sulfate .
Due to its anionic nature Jordapon SCI offers a beautiful dense and airy foam.
Jordapon SCI can be used with cleaning products


Jordapon SCI can be used as a primary or secondary surfactant, it is recommended for systems where low levels of fatty acids are needed; for example: shampoos, bath gels and liquid soaps, although their predominant commercial use is in formulations of synthetic bar soaps “Syndet bar” and “combo bars”, the latter being bars made up of a mixture of synthetic surfactant and soap.


Jordapon SCI is used Gentle, high foaming personal cleansing products, Bar toilet soaps , Pearlescent liquid soaps, Foams for facial wash, Body shampoos, Hair shampoos, and Sulfate-free shampoos
Jordapon SCI is used in syndet bars, combo bars, liquid soaps, facial cleansers, body cleansers, and shampoos.


Jordapon SCI has high foaming performance, extreme mildness, as well as soft and silky skin after-feel characteristics.
Jordapon SCI has a neutral pH and can be used in pharmaceutical preparations.
Jordapon SCI has been shown to have anti-cancer effects in clinical studies by inhibiting the growth of skin cancer cells.


Jordapon SCI also has skin conditioning properties and can be used as an emulsifier.
Jordapon SCI is typically found in concentrations between 64-68%.


Because of its excellent skin compatibility , its pronounced foam formation and foam stability, Jordapon SCI is also used in hard water, its good cleaning effect and its pleasant feeling on the skin in soap bars, the so-called syndet bars or in combination with soaps in the so-called combo bars, which are used in particular as baby soaps find.


Because of its low water solubility (approx. 0.01% = 100ppm at 25 °C), Jordapon SCI must be solubilized for use in liquid washing solutions, i.e. H. its concentration in the soap micelles can be increased.
This is done, for example, B. the addition of secondary surfactants or the exchange of sodium cations for ammonium cations [ammonium cocoyl isethionate is very water-soluble with >25% by weight at 25 ° C].


Jordapon SCI is used Hair shampoo, hand shampoo, pet shampoo, professional shampoo, baby shampoo, facial cleansers, solid shampoo.
To incorporate Jordapon SCI into a formulation, it is recommended that the chips be crushed prior to melting, as this helps to increase their melting rate.


Next, Jordapon SCI must be heated slowly on low heat in order to allow for easy mixing with other surfactants.
It is recommended that Jordapon SCI phase be mixed using a high shear stick blender.
This approach helps to prevent the excess foaming that could potentially occur if the stick blender is used to mix all ingredients together at once.


Finally, Jordapon SCI mixture can be added to the rest of the formulation.
Jordapon SCI is used to create solid cleansers and opaque liquid cleansers.
Jordapon SCI has numerous functions and applications in skincare and haircare products due to its mild, non-irritating properties.


Shampoos and conditioners uses of Jordapon SCI: As a surfactant, Jordapon SCI helps as a cleaning agent to hair and the scalp, removing dirt, oil, and impurities without causing irritation or damaging the hair.
Facial cleansers uses of Jordapon SCI: Jordapon SCI's gentle nature makes it ideal for use in facial cleansers, particularly for sensitive skin.


Bar soaps uses of Jordapon SCI: Jordapon SCI can be found in bar soaps, where it creates a creamy lather and cleanses the skin without causing dryness or irritation.
Hair styling products uses of Jordapon SCI: In hair styling products, Jordapon SCI can provide a smooth texture and aid in the even distribution of other ingredients.


Jordapon SCI is primarily a surfactant that is gentle on the surface and provides many benefits to skin and hair.
Jordapon SCI is thus commonly used in the cosmetic world.
Jordapon SCI can be used in clear / pearlescent gels.


Jordapon SCI is an anionic surfactant that gives a creamy, foaming texture to your recipes for solid cleansing products.
Jordapon SCI is derived from the fatty acids in 100% natural Coco oil.
The plant-derived Jordapon SCI adds softness to skin and hair and improves detangling.


Available in granulated form, Jordapon SCI is more convenient to use than powder because of its volatility.
To use, put the Jordapon SCI in a little water and heat the mixture in a bain-marie.
Stir until the mixture forms a paste.


You can then add it to your recipe for solid shampoo, soap or other products.
Jordapon SCI is a sulphate-free, mild anionic surfactant.
Jordapon SCI is derived from the fatty acids of coconut oil and isethionic acid, it has a very good foaming power.


Jordapon SCI is found in natural products such as solid shampoos.
Jordapon SCI gives an excellent skin feel while also possessing high foaming ability, being able to produce a rich, creamy and stable lather that will not dehydrate the skin.


Jordapon SCI is lightly scented, tending not to trigger fragrance allergies, as well as an effective moisturizer and conditioner
In hair care products, Jordapon SCI moisturizes, conditions, and softens hair, helping prevent frizz and tangling.
Jordapon SCI has emulsifying properties that increase viscosity as well as help water to cling to dirt and oil on skin and hair, so it can be easily washed away.


Jordapon SCI leaves skin and hair feeling hydrated and soft.
Jordapon SCI is perfect for adding to water-free products, as well as skin care, hair care and bath products including Shampoos, Shower Gels, Soap Bars, Personal Care Products and more.


Jordapon SCI Can Be Used In Many Different Products Including: Soap Bars, Shampoo Bars, Liquid Hand Soap, Shampoo, Baby Products, Shower Gel, Bath Bombs, Foaming Bath Butter, Bath Whip, Cream Soap, Bubble Bars, Makeup, Toiletries, Personal Hygiene Products, and Personal Care Products.
Jordapon SCI is produced by ethoxylation, which makes it an environmentally unfriendly ingredient.


Jordapon SCI is an anionic surfactant derived from coconut fatty acid and sustainable palm that are used in many cosmetic and personal care products.
In particular, Jordapon SCI is used in the preparation of skin cleansing products such as soaps and washes as well as in shampoos and other hair cleansing products.


By helping water to mix with oil and dirt, Jordapon SCI is great at rinsing dirt away from the skin and hair leaving both feeling fresh and clean.
Jordapon SCI is used in skin and hair cleansing preparations.


Jordapon SCI is used as this is a dry surfactant it can be blended into a dry formulation such as a dry shampoo, bath bomb, powdered facial cleanser or equivalent or can be added to the water phase of a standard, water based cleansing product (shampoo, shaving product, cleanser etc).


In hair care products, Jordapon SCI moisturizes, conditions, and softens hair, helping prevent frizz and tangling.
Jordapon SCI has emulsifying properties that increase viscosity as well as help water to cling to dirt and oil on skin and hair, so it can be easily washed away.


Jordapon SCI leaves skin and hair feeling hydrated and soft.
Jordapon SCI is perfect for adding to water-free products, as well as skin care, hair care and bath products including Shampoos, Shower Gels, Soap Bars, Personal Care Products and more.


Jordapon SCI Can Be Used In Many Different Products Including: Soap Bars, Shampoo Bars, Liquid Hand Soap, Shampoo, Baby Products, Shower Gel, Bath Bombs, Foaming Bath Butter, Bath Whip, Cream Soap, Bubble Bars, Makeup, Toiletries, Personal Hygiene Products, and Personal Care Products.
Mix with Jordapon SCI to other surfactants (anionic or nonionic) at a concentration of 1-10%.


Jordapon SCI is used for external use only.
Jordapon SCI is used in Shampoos, shower gels, detergent bars, bubble bath, feminine hygiene products, facial cleansers for blemished skin.
Jordapon SCI has long been used as a substitute for sodium salts obtained from animals, such as sheep and cattle.


A thin white powder is known as Jordapon SCI.
Jordapon SCI is used as a surfactant or co-surfactant (for cleansing properties and lather) in products such as shampoos, shampoo bars, body washes, and hand soaps.


Jordapon SCI's created by combining sodium isethionate with coconut oil fatty acids.
Jordapon SCI is a surfactant that cleans the skin.
In cosmetics and personal care products, Jordapon SCI is used primarily in the preparation of bath soaps and cleansing products.


Jordapon SCI is also used in the formulation of shampoos, tonics, dressings, other hair grooming aids and skin cleansing preparations.
Jordapon SCI cleans the skin and hair by helping water to mix with oil and dirt so that they can be rinsed away.
Jordapon SCI has high foaming capabilities which will not dry out your skin.


Jordapon SCI is very popular in water free products like solid shampoo bars and solid soap bars.
Jordapon SCI can be used in Shampoos, Bubble Bath products, Bath Bombs, Soap Bars and Body Wash Bases.
Jordapon SCI has been deemed safe by the Cosmetic Ingredient Review Expert Panel.


Their report surveyed products containing up to 49.4% in rinse-off formulas and 17% for leave-on products.
Its ultra-mild properties make Jordapon SCI ideal for delicate or sensitive skin, and it is often used as a plant-based alternative to animal-derived sodium salts.


Jordapon SCI has good water solubility and can be used as main surfactant or sub-surfactant in transparent formulation system.
The pH value of Jordapon SCI is between 4.5 and 6.5, which is weakly acidic, which is close to the pH value of the human body.
Jordapon SCI has high biodegradability, good compatibility, and can be compounded with most surfactants.


Jordapon SCI can be used as a main surfactant or sub-surfactant in a sulfate-free formulation system.
Jordapon SCI is widely used in personal washing and skin care products such as shower gel, shampoo, facial cleanser, hand soap, shaving foam, baby bath products, beauty soap and so on.


A gentle anionic surfactant that does not dehydrate the skin, Jordapon SCI is as a fantastic alternative to harsher, drying anionic surfactants making it great for all skin types, including sensitive or dry skin.
Makes superior hair shampoo for black hair leave the skin and hair feeling smooth and moisturized without stripping the skin/hair whatsoever.


Jordapon SCI has the characteristics of rich and fine foam, low degreasing power, low irritation to skin and hair, and good biodegradability.
Jordapon SCI can improve the combability and softness of the hair, and its mild decontamination performance makes the skin comfortable after washing.


Jordapon SCI is a mild anionic surfactant, and has fine, long-lasting and lasting foam performance, strong cleaning ability and fast foaming speed.


-Skin care uses of Jordapon SCI:
Jordapon SCI differs from other surfactants in the way that it does not strip the skin of moisture, making it feel dehydrated.
Instead, Jordapon SCI produces a rich foam that does not dry out or irritate the skin upon application


-Hair care uses of Jordapon SCI:
Jordapon SCI produces a rich creamy lather that makes the products easier to spread and feel good.
Jordapon SCI also cleanses the shafts thoroughly because of its ability to mix well with both oil and water


-Cosmetic products uses of Jordapon SCI:
Jordapon SCI reduces the surface tension of the ingredients in a formulation - allowing them to mix well.
This prevents the separation of oil based and water based ingredients and results in an even consistency of the cosmetic products



APPLICATIONS OF JORDAPON SCI IN COSMETİC PRODUCTS
Jordapon SCI is a mild surfactant for hair and skin. Upon contact with water, it creates a pleasant, thick foam.
In cleansing products, Jordapon SCI cleans and smoothens the skin without causing any irritation or dryness.
Jordapon SCI has a moisturizing, softening and smoothing effect on skin and hair.

Jordapon SCI also has emulsifying properties, giving cosmetic products a creamy texture and increasing their viscosity.
In hair care products, Jordapon SCI may decrease hair tangling and make it easier to comb.
Jordapon SCI may be used in mild cleansing products for persons with sensitive or allergy-prone skin.

Jordapon SCI dissolves dirt well, binding impurities and leaving the skin clean and moisturized.
Jordapon SCI retains its effectiveness in both soft and hard water, which makes it useful for a wider range of cosmetic applications. Thanks to its chemical structure, Jordapon SCI has many beneficial properties that make it delicate even for baby skin.

Therefore Jordapon SCI is a frequent ingredient of bathing products for children.
Jordapon SCI is biodegradable and causes no harm to the environment, so products with this ingredient are a recommended choice for any natural and ecological routine.



COSMETIC USES OF JORDAPON SCI:
Jordapon SCI is used in make-up removal and personal hygiene products, as well as plant-based cosmetics.
Applications of Jordapon SCI in cosmetics include:
*Shampoo bars,
*Cleansing bars,
*Peeling bars,
*Bath balls,
*Shampoos,
*Foam baths,
*Shaving gels and creams,
*Bathing products for children,
*Make-up removal milk.



JORDAPON SCI AT A GLANCE:
*Coconut-derived cleansing agent regarded as compatible with sensitive skin
*Known to mitigate disruption of skin’s barrier
*Produces gentle foaming action
*Deemed safe by the Cosmetic Ingredient Review Expert Panel



BENEFITS OF JORDAPON SCI:
*Jordapon SCI has excellent foam density, foam stability and lathering
*Jordapon SCI has very good lime soap dispersion and surface activity
*Jordapon SCI maintains the hydration level of skin
*Exceptionally mild, Jordapon SCI provides soft skin after-feel, ideal for irritant and blemished skin
*Jordapon SCI is compatible with soaps and anionic, non-ionic, and amphoteric surfactant
*Jordapon SCI can be used for transparent products including gels



WHAT DOES JORDAPON SCI DO IN A FORMULATION?
*Cleansing
*Surfactant



SAFETZ PROFILE OF JORDAPON SCI:
Jordapon SCI is safe for use when added under the prescribed concentrations.
Jordapon SCI is recommended to be used up to the concentrations of 50% in rinse off products and up to 17% for leave on products.
A patch test should be done prior to full usage and should be discontinued in case of any irritation.
Further, Jordapon SCI is non-comedogenic and does not cause acne breakouts.
Jordapon SCI is also biodegradable as it is derived from coconuts.



ALTERNATIVES OF JORDAPON SCI:
*SODIUM LAURYL SULFATE


HOW IS JORDAPON SCI MADE?
Jordapon SCI is produced by reacting sodium isethionate with fatty acids derived from coconut oil or other chlorides.
The mixture is then heated to remove water and distilled to remove excess fatty acids.



PROPERTIES OF JORDAPON SCI:
*Dense foam
*Solid foaming
*Anionic surfactant



BENEFITS OF JORDAPON SCI::
*Gentle on skin and eyes.
*Produces excellent foam in hard or soft water.
*Gives a feeling of softness to the skin.
*Nice smell.
*Completely biodegradable.
*High active content (82% minimum).



PREPATATION AND EXTRACTION OF JORDAPON SCI:
Presentation and extraction
Jordapon SCI can be prepared via the so-called “indirect route” by reacting higher carboxylic acid chlorides with sodium isethionate .
In industrial processes, Jordapon SCI is obtained via direct esterification of a coconut fatty acid mixture with sodium isethionate in the presence of catalysts.



SYNTHESIS OF JORDAPON SCI:
For this purpose, a coconut fatty acid mixture of different alkyl chain lengths Cn, typically C6 = 0.4% by weight; C8 = 7.6; C10 = 6.5; C12 = 47.7; C14 = 18.4; C16 = 8.9; C18 = 6.2; C18:1 = 3.7 in excess with sodium isethionate solution and zinc oxide under nitrogen at approx. 200 ° C.
After distilling off the water from the sodium isethionate solution and the water of reaction, a viscous mass is formed, which is liquefied again by adding paraffin wax.

After esterification with conversions >95%, stearic acid is added in order to lower the solidification point of the mixture below 50 °C.
When using branched fatty acids, the addition of paraffin as a consistency regulator is unnecessary and highly concentrated acyloxyethanesulfonates are obtained with high foaming properties, good hard water stability and also good water solubility (up to 30% at 20 °C).



PROPERTIES OF JORDAPON SCI:
Solid Jordapon SCI is available in flake, granule or powder form with approximately 85% active content (SCI-85).
There are also solid SCI-65 scales with around 30% fatty acid content.
Jordapon SCI is poorly soluble in water and is not long-term stable in solution at pH values ​​below 5 and above 8 due to its ester bond in the molecule.

Jordapon SCI is readily biodegradable with low affinity for bioaccumulation.
Jordapon SCI is slightly to moderately irritating to the skin and eyes.
Jordapon SCI exposure can cause minimal to mild skin irritation, although it is not skin sensitizing.



PROPERTIES OF JORDAPON SCI:
*mild to skin and eyes
*excellent foamers in hard or soft water
*impart a soft after feel to skin
*mild odor
*based upon fatty acids from natural, renewable coconut oil
completely biodegradable



COSMETIC INGREDIENTS FUNCTIONS OF JORDAPON SCI:
*Surfactant,
*Surfactant (Anionic)



BENEFITS OF JORDAPON SCI:
Jordapon SCI exhibits high foaming ability, producing a stable, rich and velvety lather that does not dehydrate the skin, making it ideal for addition to water-free products as well as skin care, hair care, and bath products.
This high-performance surfactant, Jordapon SCI, which is equally effective in both hard and soft water, is a popular choice for addition to liquid shampoos and bar shampoos, liquid soaps and bar soaps, bath butters and bath bombs, and to shower gels, to name a few foaming products.

This lightly-scented and conditioning cleansing agent, Jordapon SCI, is gentle enough for use on the delicate skin of babies, making it an ideal surfactant for makeup as well as personal care products and natural toiletries.
Its emulsifying property, which allows water and oil to mix, makes Jordapon SCI a popular ingredient in soaps and shampoos, as it encourages dirt to attach itself to them, which in turn makes it easier for it to be washed away.
Jordapon SCI's deluxe foaming capacity and conditioning effects leave the hair and skin feeling hydrated, soft, and silky-smoothe.



FEATURES AND BENEFITS OF JORDAPON SCI:
-Benefit Claims:
*Cleansing,
*High Foaming,
*Mild,
*Non-Irradiated,
*Silky Feel,
*Soft Feel

-Labeling Claims:
*Additive-free,
*Antioxidants-free,
*Clean at Sephora,
*Credo Clean Standard,
*GMO-free,
*Microplastics-free,
*Nanomaterials-free,
*Naturally Derived,
*Non-GMO,
*Not Tested on Animals,
*Preservative-free,
*Solvent-free,
*Ulta Beauty's Conscious Beauty



MARKETS OF JORDAPON SCI:
*HI&I Care,
*Personal Care


FUNCTIONS OF JORDAPON SCI:
*Anionic Surfactant



IN A NUTSHELL, JORDAPON SCI:
*Made from natural, renewable coconut oil
*Very mild to skin and eyes
*Jordapon SCI exhibits excellent foam and lather, performs well in hard water
*Jordapon SCI imparts a soft after-feel to skin or hair
*Great for solid cleansing bars, thus avoiding SLS and SLeS
*Jordapon SCI creates an opaque and creamy product when used with other surfactants in winter, but in our hot summers this effect can disappear
*Biodegradable



HIGH PURITY JORDAPON SCI PROVIDES:
+ High foaming performance,
+ Extreme mildness
+ Soft & silky skin after-feel characteristics
- Jordapon SCI is an excellent choice as a primary surfactant or secondary surfactant in liquid cleanser applications.
- Jordapon SCI is based upon fatty acids from natural, renewable coconut oil



MAIN BENEFITS OF JORDAPON SCI:
*Emollient,
*Cleansing
*Foaming Agent.



WHO SHOULD USE JORDAPON SCI:
All skin types are welcome to use it.


HOW OFTEN CAN YOU USE JORDAPON SCI?
Jordapon SCI's fine to apply every day, but it shouldn't be left on for more than a few minutes at a time, like other surfactants, to avoid irritation.


JORDAPON SCI WORKS WELL WİTH:
Jordapon SCI's compatible with a wide range of different surfactants.
To make a thicker mixture, Jordapon SCI's frequently used with natural polymers like xanthan gum and carrageenan gum.


JORDAPON SCI DOES NOT WORK WİTH:
Jordapon SCI has no known negative interactions with other substances.


HOW TO USE JORDAPON SCI:
Jordapon SCI is added to your formulation's water phase.



MECHANISMS OF ACTION OF JORDAPON SCI:
The inability of Jordapon SCI’s micelles to contribute to skin penetration was one of the reasons for its mildness.
The Jordapon SCI micelles were found to be significantly larger than the skin’s aqueous pores, implying that the SCI micelles are unlikely to enter the skin and cause more discomfort.

Surfactant, often known as a surface-active agent, Jordapon SCI is a detergent-like chemical.
When added to a liquid, Jordapon SCI lowers the surface tension, making it easier to spread and moisten.
Surfactants break down these interactions as they absorb.

Because the intermolecular interactions between the surfactant and the water molecule are substantially lower than those between two water molecules, surface tension is reduced.

Micelles occur when the concentration of surfactant is high.
The critical micelle concentration is the point at which micelles begin to form.
The primary function of surfactants is to reduce surface and interfacial tension while also stabilising the interface.



BENEFITS OF JORDAPON SCI:
Jordapon SCI has a strong foaming ability and produces a stable, rich, and velvety lather that does not dehydrate the skin, making it perfect for use in water-free products.
This high-performance surfactant, Jordapon SCI, is widely used in liquid shampoos and bar shampoos, liquid soaps and bar soaps, bath butters and bath bombs, and shower gels, to name a few foamy items.

This gently fragrant and conditioning washing agent is gentle enough for baby’s sensitive skin, making Jordapon SCI an excellent surfactant for makeup, personal care products, and natural toiletries.
Its emulsifying property, which allows water and oil to mix, makes Jordapon SCI a common ingredient in soaps and shampoos since it promotes dirt to adhere to them, making it simpler to remove.
Jordapon SCI's luxurious foaming capacity and conditioning properties leave hair and skin feeling moisturised, soft, and silky smooth.



IS JORDAPON SCI NATURAL?
Jordapon SCI cannot be considered natural.
Jordapon SCI is not known to naturally occur in plants, minerals, or animals.
While one part of Jordapon SCI's synthesis does come from coconut oil, the other half is derived from sodium bisulfate and ethylene oxide.



PROPERTIES OF JORDAPON SCI::
Jordapon SCI, is a substance naturally derived from coconut oil.
Jordapon SCI contains fatty acids and the sulfonic (isethionic acid).
To maintain its properties, Jordapon SCI requires proper storage conditions – in a cool place, away from light and heat.

Jordapon SCI is safe for external applications.
Jordapon SCI has been a subject of many research studies and has not been found to cause any significant adverse effects.
Jordapon SCI is considered safe for use in cosmetic formulations.

However, to make sure no allergic reaction occurs, a quick test may be conducted: Place a small amount of the product containing Jordapon SCI on your hand and wait for a moment, looking for any significant changes.
If no irritation develops, Jordapon SCI can be used as instructed.



STRENGTHS OF JORDAPON SCI:
Jordapon SCI is a wonderful, gentle lather.


WEAKNESSES OF JORDAPON SCI:
The larger shapes of Jordapon SCI can be a pain to melt down.
Jordapon SCI can hydrolyze if it’s in a hydrous (liquid) formulation with a pH below 6, causing formulations to become unstable.



ALTERNATIVES AND SUBSTITUTIONS OF JORDAPON SCI:
As a bare minimum you’ll need a different solid anionic surfactant.
You’ll also need to watch the active surfactant matter (you may need to use a different quantity of the new surfactant to get the same ASM level in the end product) and the pH of the final product.
Keep in mind that most solid anionic surfactants are not as gentle as Jordapon SCI.
Two options to consider would be SLSa and Sodium (C14-16) olefin sulfonate (Bio-Terge AS90).



DO YOU NEED JORDAPON SCI?
Jordapon SCI depends on what you want to make!
If you primarily want to make shampoo bars and other solid cleansing bars, I highly recommend Jordapon SCI.
If you are more interested in foaming bath products (bath salts, bath bombs, bath truffles, etc.), I’d probably choose Sodium Lauryl
Sulfoacetate (SLSa) over Jordapon SCI as it’s far more water soluble.
If your primary aim to create liquid surfactant products, I’d choose liquid surfactants and/or solid surfactants that are more water soluble (Sodium Coco Sulfate [SCS], Sodium Lauroyl Methyl Isethionate [SLMI]) than Jordapon SCI is.



SOLUBILITY OF JORDAPON SCI:
Jordapon SCI is water soluble, but not very enthusiastically.
Jordapon SCI's cousin, Sodium Lauroyl Methyl Isethionate (SLMI), is far more water soluble.



WHY DO WE USE JORDAPON SCI IN FORMULATIONS?
Jordapon SCI offers beautiful, gentle “lace glove” lather to our products.
Jordapon SCI’s also naturally acidic, so it helps our end products have a skin-friendly pH with less (or no) adjusting.



BENEFITS OF JORDAPON SCI:
*Good foam improver and stabilizer
*Very mild and non-drying
*Plant based
*Outstanding (sole) surfactant for bar soaps and syndets
*Easy to handle and formulate
*Packaging Description



BENEFITS OF JORDAPON SCI FOR SKIN:
Jordapon SCI offers benefits for nearly all skin types, particularly those with sensitive or dry skin types.
Some of these benefits include:

*Produces a silky lather:
Due to the fact that it's a surfactant, Jordapon SCI lowers the surface tension of the water, allowing the product to spread easier across the face.
In hair care products, Jordapon SCI gently cleanses hair while removing excess oil to reduce tangles and frizz, as well as allow the products to lather.

*Adding hydration and moisture:
According to Spinnato, Jordapon SCI exhibits a high foaming ability producing a stable, rich, and velvety lather that does not dehydrate the skin.
Instead of drying out the skin like other surfactants, Jordapon SCI'll leave your skin feeling hydrated and moisturized sans any irritation, redness, or dryness.

*Gently lifting away dirt, oil, and another build-up:
By bonding water and oil, Jordapon SCI has the ability to help get rid of any makeup residue, dirt, or grime that's been sitting on your face, body, or scalp all day.
This means that Jordapon SCI is an agent that helps remove the dirt and oils with the emulsification of the product.

*Preventing damage to the skin barrier:
Unlike other harsher surfactants, Jordapon SCI is kinder on the skin.
In return, explains Graf, Jordapon SCI cleanses the skin gently without damaging the moisture barrier or taking away any hydration.



SIDE EFFECTS OF JORDAPON SCI:
As of now, there are no known side effects associated with using Jordapon SCI.
However, if you have a coconut allergy, you should steer clear of the ingredient.
Since Jordapon SCI is derived from coconut oil, it should be avoided by anyone who has a coconut allergy.

Another thing to note:
If you overuse the ingredient, Jordapon SCI may be drying, particularly for those with natural or thicker textured hair types.
Jordapon SCI may strip the hair of its natural oils if you use it too often on dryer hair types, so make sure to proceed with caution.



HOW TO USE JORDAPON SCI:
Due to its gentle nature, Jordapon SCI can be used every single day.
For a body wash, opt to use Jordapon SCI twice a day.
If Jordapon SCI's a cleanser, you should only be using it two times a day at maximum.

Before using Jordapon SCI, make sure the bottle has no more than 50% SCI, advises Graf, as it can be drying.
Jordapon SCI arrives within shampoos, body washes, cleansers, and soap bars, so incorporating it into your routine is truly an effortless product that'll reap major rewards.



RECOMMENDED USAGE OF JORDAPON SCI:
Jordapon SCI is safe for regular use when formulated within the recommended concentrations for personal care products.
The Cosmetics Ingredient Review (CIR), an independent panel of expert scientists responsible for evaluating the safety of cosmetic ingredients, has established guidelines for the safe use of Jordapon SCI in various types of products.
Jordapon SCI can be used daily, but it is recommended to only be used twice on hair per day to maintain follicle health.



JORDAPON SCI HELPS TO:
*Lift and remove dirt
*Hydrate the hair and skin to protect against dryness
*Create rich, foaming lather
*Prevent frizz
*Increase product viscosity
*Moisturize, condition, and soften
*Reduce tangling
*Emulsify formulations and increase their viscosity, which contributes a creamier texture
*Lift and remove dirt
*Soothe skin
*Hydrate, condition, and soften the skin to reduce irritation, cracking, and peeling



TYPE OF INGREDIENT:
Surfactant


MAIN BENEFITS:
Jordapon SCI creates a rich lather, gently lifts away dirt and grime, and hydrates.


WHO SHOULD USE IT:
In general, Jordapon SCI's great for all skin types, particularly those with sensitive or dry skin since it's not as harsh as other surfactants.


HOW OFTEN CAN YOU USE IT:
Jordapon SCI can be used daily, but should be used twice at most for hair care, cleansing, and body products.


WORKS WELL WITH:
Emollients and humectants to help support the skin barrier.


DON'T USE WITH:
Other harsh surfactants or skin irritants to retain its maximum benefits.



JORDAPON SCI IS THE WORLD'S MOST COMMON SYNTHETİC SURFACTANT USED FOR BATH BOMBS, BODY CLEANSERS, SHAMPOOS, SOAPS, CONDITIONERS AND OTHER FOAMY AND BUBBLY PRODUCTS:
✅ Jordapon SCI has excellent properties regardless of pH and is not affected by water hardness when used as a detergent.
Jordapon SCI provides a very creamy and rich lather
✅ Anionic, foaming, sulphate-free, skin-friendly, biodegradable. Without additives, preservatives or colorantes surfactant

✅ Plant-based (coconut oil) and synthetic.
Esterified derivative of coconut oil fatty acids

✅ Jordapon SCI not only provides a consumer-perceivable smooth and moisturizing feeling but also is actually one of the mildest surfactants for skin.
Numerous studies have shown the high tolerance of skin for Jordapon SCI.

✅ Allows to formulate shampoos containing butters or oils for a nourishing and conditioning effect, without losing the washing and foaming power and without weighing down the hair.
Jordapon SCI used in combination with Sodium Coco Sulfate (SCS) to formulate solid shampoos that are soft and well tolerated by the scalp and hair, while providing a rich and creamy lather.
Jordapon SCI also makes it possible to prepare shower bars

✅ As Jordapon SCI has limited solubility in water it may recrystallise if used in a liquid shampoo.
✅ Jordapon SCI performs well in hard water areas and is biodegradable.
Jordapon SCI has a minimum of 83% active ingredient and a pH of 5.4 (35°C / 77°F) so formulae do not usually need pH adjusting

✅ No Preservatives
✅ No Antioxidants
✅ No Solvents



FUNCTIONS OF JORDAPON SCI:
*Cleansing :
Jordapon SCI helps to keep a clean surface
*Hair conditioning :
Jordapon SCI leaves hair easy to comb, soft, soft and shiny and / or confers volume, lightness and shine
*Surfactant :
Jordapon SCI reduces the surface tension of cosmetics and contributes to the even distribution of the product when it is used



PHYSICAL and CHEMICAL PROPERTIES of JORDAPON SCI:
Inci: Sodium Cocoyl Isethionate
Application: Anionic, Mild Surfactant
Appearance: White to off-white flakes or chips
CAS No.: 61789-32-0
InChIKeys: WYHCVLBWWXVCEM-UHFFFAOYSA-M
Molecular Weight: 1555.23182
Exact Mass: 288.100739
EC Number: 263-052-5
DSSTox ID: DTXSID6028070
PSA: 91.9
Appearance: White or of- white powder or crystlline power,odorless
Solubility: Very soluble in N,N-Dimethylformamide,
Soluble in methanol,Sparingly soluble inglacial acetic acid,
Very slightly soluble inchloroform, Practically insoluble in water.
Melting Point: 152°C~156°C
Melting Point: 191-194°C
pH: 6.0-8.0
Solubility: Soluble in water
INCI: Sodium Cocoyl Isethionate
CAS# 61789-32-0 / 61788-47-4
Physical Form: Solid Powder
Appearance: White to Off-White Powder
Odor: Characteristic
pH (35°C, 10% Solution): 4.0 – 6.0
Active Substance: min. 82%
Free Fatty Acids: max. 13.0%
Solubility: Water
Typical Usage Rates: 3 – 40% depending on formulation



FIRST AID MEASURES of JORDAPON SCI:
-First-aid measures general:
If you feel unwell, seek medical advice.
-First-aid measures after inhalation:
Assure fresh air breathing.
Allow the victim to rest.
-First-aid measures after skin contact:
Wash with plenty of water.
-First-aid measures after eye contact:
Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
-First-aid measures after ingestion:
Rinse mouth.



ACCIDENTAL RELEASE MEASURES of JORDAPON SCI:
-Personal precautions, protective equipment and emergency procedures:
--For non-emergency personnel:
*Protective equipment:
Wear recommended personal protective equipment.
*Emergency procedures:
Ventilate area.
-Environmental precautions:
Prevent entry to sewers and public waters.
-Methods and material for containment and cleaning up:
*Methods for cleaning up:
On land, sweep or shovel into suitable containers.
Collect spillage.



FIRE FIGHTING MEASURES of JORDAPON SCI:
-Extinguishing media:
*Suitable extinguishing media:
Use CO2.
Dry powder or water mist extinguishers only
-Advice for firefighters:
*Firefighting instructions:
Evacuate area.



EXPOSURE CONTROLS/PERSONAL PROTECTION of JORDAPON SCI:
-Control parameters:
No additional information available
-Exposure controls:
*Hand protection:
Protective gloves
*Eye protection:
Chemical goggles or safety glasses
*Skin and body protection:
Wear suitable protective clothing
-Other information:
Do not eat, drink or smoke during use.



HANDLING and STORAGE of JORDAPON SCI:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep only in the original container in a cool, well ventilated place away from:
Keep container closed when not in use.



STABILITY and REACTIVITY of JORDAPON SCI:
-Reactivity:
No additional information available
-Chemical stability:
Stable under normal conditions



SYNONYMS:
jordapon SCI
Sodium Cocoyl Ethyl Ester Sulfonate
Fatty Acids, Coconut Oil, Sulfoethyl Esters, Sodium Salts
fatty acids coco 2-sulfoethyl esters sodium salts
fatty acids coconut oil sulfoethyl esters sodium salts
fatty acids, coco, 2-sulfoethyl esters, sodium salts
fatty acids, coconut oil, sulfoethyl esters, sodium salts
igepon AC-78
Fatty acids, coco, 2-sulfoethyl esters, sodium salts
coconut fatty acid 2-sulfoethyl ester sodium salt
coconut fatty acid, 2-sulfoethyl ester, sodium salt
Sodium cocoyl isethionate 85%
SODIUM 2-HYDROXYETHANE COFA SULFONATE
coconutfattyacid,2-sulfoethylester,sodiumsalt
DISODIUM MANGANESE EDTA CONTENT 12.5
Fattyacids,coco,2-sulfoethylesters,sodiumsalts
fattyacids,coconutoil,sulfoethylesters,sodiumsalts
jordaponci
sodiumcocoylisothionate


K 100
Synonyms: Hexamethylenediamine Tetra (methylene Phosphonic acid) (K6);K6HMDTMP cas :38820-59-6
KALSIYUM STEARAT
KAOLIN; Aluminum Silicate; Silicic acid, aluminum salt; Aluminosilicic acid; Kieselsäure, Aluminiumsalz (German); ácido silícico, sal de aluminio (Spanish); Acide silicique, sel d'aluminium (French); China clay; Kaolinite; Kaopectate; Porcelain clay; cas no: 1332-58-7
KAOLINE 3
Inci : kaolin, Cas : 1332-58-7, EC : 310-194-1, Ce produit est du silicate naturel d’aluminium raffiné qui contient un agent dispersant approprié,
Kaolin light BP
C-8 Acid; Neo-fat 8; n-Caprylic Acid; Capryloate; Octoic acid; Octic acid; 1-Heptanecarboxylic acid; n-Octanoic Acid; n-Octic acid; n-Octylic acid; Octanoic Acid cas no: 124-07-2
KAOWAX EB-G
Kaowax EB-G is a kind of waxy amides with high melting point and low viscosity in molten state.
Kaowax EB-G is white granule powder.
In the molten state at high temperature, the resin and solvent, Kaowax EB-G, have good compatibility.


CAS Number: 110-30-5
Chemical name: Ethylene Bis-Stearamide (EBS)
Chemical family: Amide


Kaowax EB-G is a lubricant and release agent, mainly used in thermal plastics such as: ABS resin, PS , PVC and so on.
Kaowax EB-G is a white solid that provides a slippery coating for a variety of applications.
Kaowax EB-G has minimum impact to low temperature properties.


Kaowax EB-G's industrial products are slightly yellow particles or white powder, non-toxic, and have no side effects on the human body.
Kaowax EB-G is a white solid of low toxicity that provides a slippery coating for a variety of applications.
Kaowax EB-G is derived from stearic acid and ethylenediamine.


Kaowax EB-G has high stiffening of the asphalt binder.
Kaowax EB-G increase Performance Grade (PG) of asphalt.
Kaowax EB-G powder is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.


Kaowax EB-G has no influence on the transparency of the Polymers.
Kaowax EB-G is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Kaowax EB-G is derived from the reaction of ethylenediamine and stearic acid.


Kaowax EB-G is a white solid of low toxicity that provides a slippery coating for a variety of applications.
Kaowax EB-G is based on a non-vegetable origin, secondary bis-amide.
Kaowax EB-G offers mold release benefits in polyamides (nylon).


Kaowax EB-G improves viscosity of asphalt at different ranges of temperatures.
Kaowax EB-G is a secondary bis-amide additive.
Kaowax EB-G has good anti-blocking properties in polyolefins.


Kaowax EB-G is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Kaowax EB-G is derived from the reaction of ethylenediamine and stearic acid.
Kaowax EB-G is fine solid powder @25°C.


Kaowax EB-G is a synthetic wax with high melting point.
Kaowax EB-G is a hard and brittle white high melting point wax.
Kaowax EB-G has a shelf life of 365 days.


Kaowax EB-G is also available in bead form.
Kaowax EB-G is an amide wax.
Kaowax EB-G by MLA Group has low acid value ( free fatty acid ), high melting point, and excellent white colour, and high purity.


Synthhetic wax having high melting point, Kaowax EB-G has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.
Kaowax EB-G is white granule powder.


Kaowax EB-G is a hard and brittle white high melting point wax, it's industrial products are slightly yellow fine particles, insoluble in most solvents at room temperature, stable to acids and bases, and aqueous media, soluble in hot chlorinated hydrocarbons and aromatic hydrocarbons solvents, it’s powder slippery feeling strong, above 80 ℃ to water with wettability of the compound.


Kaowax EB-G is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
Kaowax EB-G is white spherical particle, non-toxic and no side effect on humans.
Kaowax EB-G is insoluble in most organic solvents at room temperature.


Kaowax EB-G is stable to acid, alkali and water medium.
Kaowax EB-G is soluble in hot chlorinated hydrocarbons and aromatic hydrocarbon solvents.
Kaowax EB-G is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Kaowax EB-G is derived from the reaction of ethylenediamine and stearic acid.
Kaowax EB-G also functions as an external lubricant for PVC and a process aid for polyolefins.
Kaowax EB-G is suitable for composites, styrenics and rubber.


Kaowax EB-G is white or slight yellow powder or granule
Kaowax EB-G is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Kaowax EB-G is derived from the reaction of ethylenediamine and stearic acid.


Kaowax EB-G acts as a slip and anti-block additive.
Kaowax EB-G disperses evenly through the polymer in the melt phase, and migrates to the surface where it forms a thin lubricating layer that reduces coefficient of friction between surfaces and reduces unwanted adhesion.


Kaowax EB-G is ethylene-bis-stearamide of non-vegetable origin.
Kaowax EB-G is a secondary bis amide effective as an anti-block agent and process aid for polyolefins.
Kaowax EB-G is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.


Kaowax EB-G is an amide wax of type Kaowax EB-G.
Kaowax EB-G is compatible with styrene & styrenic copolymer, PVC, PO and PS.
Kaowax EB-G exhibits good thermostability and excellent slip properties.



USES and APPLICATIONS of KAOWAX EB-G:
Kaowax EB-G is used as a lubricant in ABS, PS, PP, engineering plastics, PVC and thermosetting plastics.
Kaowax EB-G is used Anti-Blocking Agent, Release Agent, Slip Agent, Flow Promoter, and Hot-Melt Adhesive
Kaowax EB-G provides typical slip and anti-blocking characteristics to all polymers.


The recommended dosage levels are 500-2000 ppm in films and 0.2-1.0% in molding applications.
Kaowax EB-G powder does not affect the transparency of polymers and acts as lubricant in a wide variety of polymers like PVC, PO, PS and engineering plastics.


Kaowax EB-G is added in the coating production to increase the uniform dispersion of pigment and filler, improve the surface leveling property of baking paint, prevent the stripping off of paint film and improve water-proof and acid-resistant and alkali-resistant property.
Kaowax EB-G improves flow and has no influence on transparency of polymers.


Kaowax EB-G is used as processing auxiliary of rubber. Besides the lubricant demoulding property and modifying performance of filler surface, it can raise the surface fineness of rubber pipes and rubber plates to act as rubber surface polishing agent.
Kaowax EB-G acts as a lubricant, release & antiblocking agent for all engineering resins and dispersing agent for masterbatch applications.


Kaowax EB-G is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Kaowax EB-G is used as lubricant with good inner or outer lubricant action and has good coordination when used together with other lubricants as high grade alcohols, aliphatic acid esters, calcium stearate and paraffin.
Kaowax EB-G has apparent melting point of wax and asphalt.


Kaowax EB-G is used as nucleation transparency agent to reduce the nucleating time in compounds such as polyolefins, polyformaldehyde and polyamide, promote the structure of resin to become fine, thus improve the mechanical property and transparency of the products.
Kaowax EB-G is used in powder metallurgy.


Kaowax EB-G derived from stearic acid with ethylene diamine is a synthetic was used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability.
Kaowax EB-G is used as defoamer in latex, paper processing and fiber processing.


Lubrication performance is excellent, anti-calcium salt ability is strong, drag reduction effect is good, used for drilling in saturated brine to reduce power consumption.
Kaowax EB-G is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.


Kaowax EB-G is used in the following areas: formulation of mixtures and/or re-packaging.
Kaowax EB-G is also used as a release agents, antistats, and antifoaming agent.
Kaowax EB-G is used as defoamer/ anti-foaming agent and coating component of paper for paper-making industry.


An addition of 0.5-1 % of Kaowax EB-G can not only prevent the occurrence of air bubbles but also make the plastic bags be slippery so as to be opened easily.
Kaowax EB-G is used as a dispersant in masterbatches and flame retardant materials.


Kaowax EB-G is used as additive EBS can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.
Chemical pigments are lubricated in plastics, inks, coatings, anti-caking, etc., dispersing performance, defoaming agent in powder metallurgy, demoulding in molds.


Kaowax EB-G migrates to the surface of the polymer where it forms a thin lubricating layer.
As Kaowax EB-G has good wearable performance and smoothing performance, fits for improving polishing performance of lacquer, air release of surface with holes, Kaowax EB-G is also well used as dulling agent for polishing furniture and printing ink.


Functions in plastics: lubrication, dispersion, hanging foam, anti-caking , demoulding ; processing technology: extrusion, injection molding, calendering, fine particle size 325 mesh, low addition amount, 0.5%~1%.
Application of Kaowax EB-G: Water treatment


Kaowax EB-G is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Kaowax EB-G can also be used as a process aid, for example to improve dispersion of fillers.


Kaowax EB-G is also used as release agents, antistatic agents, and antifoaming agents.
Kaowax EB-G is used as an internal and external slip agent in many thermoplastic and thermosetting plastics, the most representative ones are ABS, PS, ABS, PVC, also used in PE, PP, PVAC, cellulose, Accurate, Nylon, phenolic-Resin, amino plastics.


Kaowax EB-Ghas a good finish and good film release.
Kaowax EB-G is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Kaowax EB-G is used for the manufacture of: rubber products and plastic products.
Kaowax EB-G is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.
Kaowax EB-G is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.


Kaowax EB-G is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Because of it's excellent lubricating properties, Kaowax EB-G is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
Kaowax EB-G is used as processing aid for resins and polymers and as defoaming agent.


Kaowax EB-G is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits.
Kaowax EB-G is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.


Kaowax EB-G is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Kaowax EB-G is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Kaowax EB-G is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Because of its excellent lubricating properties Kaowax EB-G is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
Kaowax EB-G is non-toxic and can be dispersed evenly through the polymer in the melt phase.


Kaowax EB-G is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
Kaowax EB-G is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.


As a lubricant of polyformaldehyde, the addition amount is 0.5%, which improves the melt flow rate and the film release, and the whiteness, thermal stability and physical index of polyformaldehyde all reach the superior index.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.


Kaowax EB-G not only has good external lubrication effect, but also has good internal lubrication effect, which improves the fluidity and demoulding property of melted plastic in plastic molding process, thus improving the yield of plastic processing, reducing energy consumption, and making the product obtain high surface smoothness and smoothness.


Cosmetic Uses of Kaowax EB-G: viscosity controlling agents
Kaowax EB-G can be found in industrial use: in processing aids at industrial sites, formulation in materials and as processing aid.
Kaowax EB-G is traditionally used as lubricant and binder for cold compaction of powdered metal parts.


Kaowax EB-G is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Kaowax EB-G is an internal additive and can be incorporated into resin as supplied or via masterbatch / pre-blend.
Kaowax EB-G can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


Kaowax EB-G has proven mold release benefits in nylon and is a lubricant for PVC.
Kaowax EB-G is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.


Kaowax EB-G is used as a processing aid for resins and polymers and as a defoaming agent.
Kaowax EB-G is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Kaowax EB-G is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Kaowax EB-G can also be used as a process aid, for example to improve dispersion of fillers.


Kaowax EB-G is used as an additive for hot melt adhesives.
Kaowax EB-G provides typical slip and anti-blocking characteristics to all polymers e.g. in films.
Kaowax EB-G is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.


Useful as defoamer for paper making and textile processing .
Kaowax EB-G can be found in industrial use: in processing aids at industrial sites, as processing aid, in the production of articles, formulation in materials, formulation of mixtures and of substances in closed systems with minimal release.


Kaowax EB-G is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Because of it's excellent lubricating properties, Kaowax EB-G is widely used internally and/or externally in most plastics such as ABS, PS, PP, etc.
Kaowax EB-G is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.


Kaowax EB-G is compared with traditional lubricants such as paraffin wax, polyethylene wax, stearate, etc.
Kaowax EB-G is used as additive Ethylenebisstearamide can be incorporated directly into polymers to prevent any unwanted adhesion.
Kaowax EB-G is used as Release agent and flow promoter for all engineering resins, Styrenics and their copolymers.


Kaowax EB-G is used Dispersing agent for masterbatch applications, preferably for engineering resins and PVC, and Modifier in textile auxiliaries
In the processing of ABS, AS, hard PVC, polyformaldehyde, polycarbonate, polyurethane and phenolformaldehyde resins, Kaowax EB-G is used as lubricant demoulding agent with a quantity of 0.5~1.5 %.


Kaowax EB-G is used as anti-adhesive agent for various polymer film or sheets.
Kaowax EB-G can remarkably enhance the heat-resistant and weather-resistant properties while coordinating with chief stabilizer in formulation of inorganic filler for PVC and polyolefin.


Kaowax EB-G can decrease the viscosity of asphalt and improve it’s softening point and weathering resistance when added to asphalt.
Added in the manufacturing process of dope and oil paint to enhance salt mist and dampproof effect and to improve performance of paint remover.
Kaowax EB-G can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.


Kaowax EB-G is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Kaowax EB-G is used in powder metallurgy.
Kaowax EB-G is used as additive Kaowax EB-G can be incorporated directly into polymers to prevent any unwanted adhesion.


Kaowax EB-G can be found in products with material based on: rubber (e.g. tyres, shoes, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).
Kaowax EB-G is used to prevent the adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Experience has shown that simple manual mixing prior to processing will normally give an acceptable dispersion though, mechanical means are preferred.
Typical addition levels vary depending on polymer and lubrication required.
Kaowax EB-G acts as a slip and anti-block agent, mold release agent and lubricant for PVC.


Chemical fiber: Kaowax EB-G can improve the heat and weather resistance, fluidity of polyester, polyamide fiber, and give a certain anti-static effect.
Hot-Melt Adhesive Applications of Kaowax EB-G: Release agent and flow promoter for all engineering resins, Styrenics and their copolymers.
Kaowax EB-G can also be a binder in the precise engineering metal part.


Due to it's good dispersing ability and surface migration Kaowax EB-G can be used in printing inks.
A field of application is the bitumen industry: When used in asphalt binder for road making (asphalt modifiers), Kaowax EB-G increases its softening point and enhances its visco-elasticity.


Kaowax EB-G can help to increase the melting point of petroleum products; lubricant and corrosive agent of metal wire drawing.
Kaowax EB-G is used for lubricant of plastic and metal molding, adhesion preventives, viscosity modifier, anti-corrosion of wax, water resistance of coating and spray paint.


Kaowax EB-G is used in the following areas: formulation of mixtures and/or re-packaging.
Kaowax EB-G is used for the manufacture of: rubber products and plastic products.
Kaowax EB-G can be found in industrial use: formulation of mixtures, formulation in materials, as processing aid, manufacturing of the substance and in processing aids at industrial sites.


Kaowax EB-G can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).
Kaowax EB-G can also be used as a process aid, for example to improve dispersion of fillers.
Kaowax EB-G is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.


Kaowax EB-G is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Kaowax EB-G is used as processing aid for resins and polymers and as defoaming agent.
Kaowax EB-G is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.


Kaowax EB-G is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Kaowax EB-G has proven mould release action in polyamides, and is a lubricant for PVC.


Kaowax EB-G is a bis-amide anti-blocking additive used to prevent blocking and as anti-tack of adhesives.
In synthetic fiber industry, Kaowax EB-G can improve the heat-resistant, weather-resistant property of polyester and polyamide and bring about certain antistatic effects.


Kaowax EB-G is used in the spinning of antistatic nylon fiber as additive and also is able to reduce the breaking of yarn.
Kaowax EB-G improves the kneading, processing and vulcanization performance of rubber grains in the processing of rubber.
In nitrocellulose lacquers, Kaowax EB-G can bring about the flatting action.


Kaowax EB-G is used as lubricant in powder metallurgy (PM) steels to reduce the inter-particle and die-wall friction during pressing and hence improve powder compressibility and ejection of the component from the compaction tool.
Kaowax EB-G can help to increase the smoothness and fineness for insulator layer of electric power and cable.


Chemical fiber: Kaowax EB-G can improve heat and weather resistance performance of polyester and polyamide fiber, and has some anti-static effect.
Kaowax EB-G can be found in: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Kaowax EB-G is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.
Pigment and filler: Kaowax EB-G can be used as pigment dispersant of plastic , fiber, such as ABS, PS, polypropylene fibre and PET fiber and other color masterbatch.


Kaowax EB-G is used in the following products: lubricants and greases, polymers, washing & cleaning products, inks and toners, metal working fluids, textile treatment products and dyes and coating products.
Kaowax EB-G is used Lubricant in powder metal molding, rubber, adhesives, coatings, wire drawing, wood plastic composite, Defoamer in paper, Lubricant for Polyacetals, Water repellent for paper, Intermediate for defoamers, and Delustering agent for furniture finishes and printing inks.


As Kaowax EB-G has strong cohesions with pigment or other filler, Kaowax EB-G can improve the dispersion and coupling property of fillers in the polymers to enhance the commercial value of the products.
Kaowax EB-G is added to oil based defoamers to improve foam knock down.


Kaowax EB-G can also be used as a process aid, for example to improve dispersion of fillers.
Kaowax EB-G is used internal and external lubricants with sexual and non-sexual functions are more conductive to lubrication, anti-blocking agents, high gloss and excellent antistatic properties.


Kaowax EB-G is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Kaowax EB-G is used in powder metallurgy.


Kaowax EB-G is used Raw materials, Ethylenediamine Trap Stearic acid, Preparation Products, defoaming agent OTD
Kaowax EB-G, a new plastic lubricant developed in recent years, is widely used in the molding and processing of PVC products, ABS, high impact polystyrene, polyolefin, rubber and plastic products.


-Paint, Ink:
*Adding 0.5~2% Kaowax EB-G can improve the effect of salt spray and moisture resistance in the manufacture of paint and lacquer.
*Adding Kaowax EB-G in the paint can improve the performance of the paint stripper and can improve the leveling of the baked enamel surface.
*Kaowax EB-G can be used as a matting agent in furniture polishing agents and printing ink.
*After micronization (particle size: d50 about 6μ, d 90 about 12μ), Kaowax EB-G has excellent anti-abrasion and smoothness and can be used in lacquer systems to improve polishability and degassing on a porous surface.


-Other uses of Kaowax EB-G:
*Melting point rising agent for petroleum products
*Lubricant and anti-corrosion agent for metal drawing
*Potting material for electrical components; defoaming agent and paper coating ingredient for paper industry
*Kaowax EB-G is used as a defoaming agent and permanent water pulling agent for dyeing works in textile dyeing and finishing
*Adding this product in asphalt can reduce the viscosity of asphalt and improve the softening point, water-resistance and weather resistance of asphalt.


-Pigment, filler dispersant:
*Kaowax EB-G is used as a pigment dispersant for plastic.
*Pigment dispersant for chemical fiber masterbatches, such as ABS, PS, polypropylene, polyester masterbatches.
*Kaowax EB-G can also be used as diffusion powder for plastic color matching.
*Depending on the amount of pigment and filler added, the addition amount is 0.5~5%.


-Plastic uses of Kaowax EB-G:
Lubricants inside or outside many plastics such as ABS, PS, AS, PVC, PE, PP, PVAC, cellulose acetate, nylon, phenolic resin and amino plastics.
Kaowax EB-G has a good surface quality and demoulding performance.


-Consumer Goods:
*Appliances & Electronics
*Adhesives & Sealants: Industrial & *Assembly Adhesives
*Electronics Adhesives
*Industrial Manufacturing
*Healthcare & Pharma — Medical
*Medical Tapes & Adhesives
*Electrical & Electronics — Packaging & Assembly
*Adhesives & Sealants
*Adhesive & Sealant Type


-Mode of action:
Kaowax EB-G can be dispersed evenly through the polymer in the melt phase.
Kaowax EB-G migrates to the surface of the polymer where it forms a thin lubricating layer.
This layer reduces the coefficient of friction between surfaces and prevents any unwanted adhesion.


-Rubber:
Synthetic resin and rubber will have good anti-adhesive and anti-caking effect by adding Kaowax EB-G in their emulsion.
Kaowax EB-G has a good effect to the increase surface gloss when added to rubber products.


-Release agent:
Phenolic resin for sand casting with Kaowax EB-G can be used as a release agent.
-Powder Coating:
Kaowax EB-G can be used as flow additives for powder coatings.


-Applications of Kaowax EB-G:
*Adhesives & sealants
*Composites
*Inks


-Coatings and printing ink:
When manufacturing coating and painting, Kaowax EB-G can improve the effect of salt spray and moistureproof by adding Kaowax EB-G.
Kaowax EB-G can help to improve the paint stripper performance of paint when added, and to increase the leveling performance of baking enamel varnish.


-Applications of Kaowax EB-G:
*Intended resin (Lubricant use)
*ABS, PS, PVC, Phenol resin, Engineering plastics
*Lubricant for ABS resin, polystyrene and copolymers, PVC and polyolefin.
*Lubricant for Shell molding



PROPERTIES OF KAOWAX EB-G:
*Typical lubricants for improving flowability of ABS and PS.
*They prevent blocking of flexible PVC.



BENEFITS of KAOWAX EB-G:
-Excellent slip and anti-blocking properties when used in PVC, engeneering resins, PO film and compounds
-Good release properties in PVC and thermoplastics
-Improves flow of polymers
-No influence on transparency of polymers
-Wide food approval



PHYSICAL and CHEMICAL PROPERTIES of KAOWAX EB-G:
Appearance: White, waxy crystals
Odor: Odourless
Melting point: 144 to 146 °C (291 to 295 °F; 417 to 419 K)
Flash point: 280 °C (536 °F; 553 K)
Physical state: Beads
Color: white
Odor: odorless
Melting point/range: 144 - 146 °C - lit.
Initial boiling point and boiling range: 260 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: ca.270 °C - DIN 51758
Autoignition temperature: ca.380 °C at 1.013 hPa - DIN 51794
Decomposition temperature: > 200 °C -
pH: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: ca.10 mPa.s at 150 °C
Water solubility at 20 °C: insoluble

Partition coefficient: n-octanol/water log Pow: 13,98 at 25 °C
Vapor pressure: Not applicable
Density: 1 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 720.34 °C. @ 760.00 mm Hg (est)
Flash Point: 213.00 °F. TCC ( 100.70 °C. ) (est)
logP (o/w): 14.787 (est)
Soluble in: water, 2.049e-010 mg/L @ 25 °C (est)

Molecular Weight: 593.0
XLogP3-AA: 15.7
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 35
Exact Mass: 592.59067967
Monoisotopic Mass: 592.59067967
Topological Polar Surface Area: 58.2 Ų
Heavy Atom Count: 42
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
vapor pressure: 0.000023 Pa (20 °C)
refractive index: 1.4670 (estimate)
Flash point: 280℃
storage temp.: 2-8°C
solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
pka: 15.53±0.46(Predicted)
form: beads
Appearance: Powdery
Smell: No smell
Color (Gardner): ≤3#
Melting Point (℃): 141.5-146.5
Acid Value (mgKOH/g): ≤7.50
Amine value (mgKOH/g): ≤2.50
Moisture (wt%): ≤0.30
Mechanical impurity: Φ0.1-0.2mm(individual/10g)



FIRST AID MEASURES of KAOWAX EB-G:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of KAOWAX EB-G:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of KAOWAX EB-G:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of KAOWAX EB-G:
-Control parameters
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of KAOWAX EB-G:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of KAOWAX EB-G:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
N,N-ethylenedi(stearamide)
1,2-distearamidoethane
N,N-Ethylenebisoctadecanamide
N,N'-ethylene bis-stearamide
N,N'-ethane-1,2-diyldioctadecanamide
2,5-dihexadecylhexanediamide
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
N,N′-Ethylenedi(stearamide)
Ethylene distearylamide
N,N′-(Ethane-1,2-diyl)di(octadecanamide)
ETHYLENE-BIS-STEARAMIDE
waxc
EBSA
advawax
acrawaxc
acrowaxc
lubrolea
5-AC-13C4
acrawaxct
110-30-5
N,N'-Ethylenebis(stearamide)
Plastflow
Ethylene distearamide
N,N'-(Ethane-1,2-diyl)distearamide
Advawax
Acrowax C
Acrawax CT
Lubrol EA
Ethylenedistearamide
Microtomic 280
Advawachs 280
Ethylenebis(stearylamide)
Abril wax 10DS
Carlisle 280
Nopcowax 22-DS
Ethylenebisstearoamide
Advawax 275
Advawax 280
Carlisle Wax 280
Armowax ebs-P
Ethylenebis(stearamide)
Octadecanamide, N,N'-1,2-ethanediylbis-
N,N'-Ethylenebisoctadecanamide
1,2-Bis(octadecanamido)ethane
Chemetron 100
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-Ethylenedistearamide
Ethylenediamine steardiamide
Ethylenediamine bisstearamide
N,N'-Distearoylethylenediamine
Ethylenebisstearamide
N,N'-Ethylenebisstearamide
NN'-Ethylenebis(stearamide)
Stearic acid, ethylenediamine diamide
Ethylenebisoctadecanamide
Octadecanamide, N,N'-ethylenebis-
UNII-603RP8TB9A
N-[2-(octadecanoylamino)ethyl]octadecanamide
N,N-Ethylenebis(stearamide)
603RP8TB9A
N,N'-ethane-1,2-diyldioctadecanamide
Acrawax C
Kemamide W 40
N,N'-Ethylenedi(stearamide)
WAX C
N,N-Ethylenebisstearamide
CCRIS 2293
ethylene bisstearamide
HSDB 5398
Ethylene bis stearamide
Ethylene bis(stearamide)
EINECS 203-755-6
NSC 83613
N,N'-Ethylene bisstearamide
AI3-08515
N,N'-ethylene-bis-stearic amide
Abluwax EBS
Armowax EBS
Dorset WAX
C38H76N2O2
N,N'-ethylenebis
Glycowax 765
Kemamide W-39
Kemamide W-40
N,N'-1,2-Ethanediylbisoctadecanamide
Uniwax 1760
EC 203-755-6
Ethylene Bis Stearamide SF
SCHEMBL19975
Octadecanamide,N'-ethylenebis-
DTXSID4026840
NSC83613
MFCD00059224
NSC-83613
ZINC85733714
AKOS015915120
Octadecanamide,N'-1,2-ethanediylbis-
DS-6811
E0243
FT-0629590
V0595
D70357
N,N'-Ethylenebis(stearamide), beads, A802179
Q5404472
W-108690
2,5-dihexadecylhexanediamide
N,N'-(Ethane-1,2-diyl)distearamide
Plastic additive 03, European Pharmacopoeia (EP)
n,n'-ethylenebisoctadecanamide (mixture of fatty acid amides) (consists of c14, c16 and c18)
N,N'-Ethylenedi(stearamide)
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
Ethylene distearylamide
Ethylene bisstearamide
Ethylene distearamide
EBS
1,2- Bis(octadecanamido)ethane
Ethylenebisoctadecanamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
N-(2-stearamidoethyl)stearamide
N,N'-Distearoylethylenediamine
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethylenedistearamide
n,n'-Ethylene distearylamide
Octadecanamide


KAPRIK/KAPRILIK ASIT 
KERATIN, N° CAS : 68238-35-7, Nom INCI : KERATIN, N° EINECS/ELINCS : 269-409-1, Ses fonctions (INCI): Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance.Agent d'entretien de la peau : Maintient la peau en bon état
KATHON 893
Kathon 893 This product is a powerful fungicidal compound, which can be used as an additive in aqueous metalworking fluids. KATHON 893 MW offers excellent anti-fungal protection at use rates of 55 to 170 ppm on a post-addition basis. KATHON 893 MW is also compatible with KATHON 886 MW.STORAGE AND HANDLINGThe expected shelf life for this product is 2 years under normal storage conditions. This product, like most chemicals, should be stored out of direct sun light in an area where the temperature is between 40ºF (4.4ºC) and 110ºF (43ºC).SAFETY DATAThis product is very hazardous and proper handling and storage is critical. Avoid contact with skin and eyes. Prior to using this product, please consult the Material Safety Data Sheet for instructions regarding safe handling. EPA approved, fully tested and widely used/accepted standard of the industry Can be used in a maintenance dose or in a kill dose Quickly disperses for immediate impact on fungi Compatible with KATHON 886 MW, will not deactivate any active ingredients in the full-spectrum biocide. Soluble, synthetic, and semi-synthetic metalworking fluids or coolants provide an excellent environment for the growth of various microorganisms, including bacteria, mold, and yeast. If allowed to grow, these organisms can have detrimental effects on the fluids. For example, bacteria, which can grow very quickly, can destroy the integrity of the fluid by discoloration, destroying lubricity characteristics, and causing emulsions to split. Bacteria can also reduce the pH of the fluid, which can promote corrosion. Some forms of bacteria have objectionable odors. Fungi typically grow more slowly than bacteria, but can form large masses which clog filters and lines and in some cases lead to system shutdown; fungi also generate foul odors and can cause corrosion. The increased use of synthetic fluids over the past few years has led to an even greater need for the enhanced fungal control that Kathon 893 MW Biocide can provide. Product Name Kathon 893 Synonyms 2-Octyl-4-isothiazolin-3-one 3(2H)-Isothiazolone, 2-octyl- Kathon LP Preservative Octhilinone Ultrafresh DM 25 Vinyzene IT 3000DIDP CAS 26530-20-1 Formula C11H19NOS Molecular Weight 213.34 EINECS 247-761-7 RTECS NX8156900 RTECS Class Agricultural Chemical and Pesticide; Drug; Primary Irritant Merck 12,6853 Beilstein/Gmelin 1211137 EC Index Number 613-112-00-5 EC Class Toxic; Harmful; Corrosive; Sensitising; Dangerous for the Environment Physical and Chemical Properties Appearance Clear dark amber liquid. Solubility in water Insoluble Boiling Point 120 Vapor Pressure 3 Density 1.040 g/cm3 (20 C) Usage Used to kill fungus. For Tankside and Concentrate Kathon 893 MW Biocide is a broad-spectrum fungicide that has been recommended and widely used for tankside control of fungi in metalworking central systems. Kathon 893 MW is also an effective fungicide for use in many metalworking fluid concentrates with the appropriate stabilizer package. Due to the wide variations in metalworking fluid formulations, laboratory or small-scale tests are recommended to evaluate Kathon 893 MW in usedilution and concentrate metalworking fluids before they are commercialized. Kathon 893 MW is a highly effective, industrial fungicide that exhibits excellent fungistatic and fungicidal activity against fungi, including yeasts and mold, and Gram-Positive bacteria, and limited activity against Gram-Negative bacteria. Commonly known as octhilinone, 2-n-octyl-4-isothiazolin-3-one is the active ingredient of Kathon 893 MW. It is supplied as a 45 percent active liquid in propylene glycol. The information in this brochure has been compiled to familiarize the reader with Kathon 893 MW technology, to communicate the tremendous benefits of this product, and to provide directions for safe and efficient use of the product. By following the precautions outlined in this brochure, on the product label, and on the Dow Safety Data Sheet (SDS), Kathon 893 MW can be safely handled. The following are typical properties of Kathon 893 MW Biocide; they are not to be considered product specifications. Appearance: ..................................................................................... Yellow to amber liquid Color (VCS): .............................................................................................................. 8 max. Odor: ................................................................................................................. Mildly sweet Specific gravity @ 24°C: .............................................................................................. 1.03 Flash point, °C (Pensky Martens Closed Cup): ............................................................... 93 Viscosity Brookfield @ 20°C, cps: ................................................................................... 40 Melting point, °C: ............................................................................................................ -40 Boiling point, °C: ............................................................................................................ 188 Vapor pressure, active ingredient @ 25°C: ................................................... 3.7 x 10-5 torr Solubility The solubility data provided below were determined at ambient temperatures (20 to 25°C). The solubility and stability of the active ingredient may be affected when the temperature is lowered to 0°C or increased to 60°C. • Kathon 893 MW Biocide is soluble in methanol, ethanol, propylene glycol, acetone, ethyl ether, ethyl acetate, chloroform, butyl Cellosolve, corn oil, and mineral oil. • The solubility of Kathon 893 MW in toluene is 25% w/v. • The solubility of Kathon 893 MW in water at 25°C is 480 ppm (active ingredient), although this may be increased by using suitable surfactants and emulsifiers. • Kathon 893 MW is insoluble in heptane. Compatibility In concentrate and use-dilution metalworking fluids, the compatibility of Kathon 893 MW Biocide is concentration-dependent and varies from formulation to formulation. It is compatible with most metalworking fluid additives, including surfactants and amines. Compatibility with amines may vary by the type, concentration and pH. Strong reducing agents, such as sulfides, mercaptans, bisulfites and metabisulfites, or strong oxidizing agents, such as hypochlorites, may affect the efficacy of Kathon 893 MW. Laboratory or small-scale tests are recommended in order to evaluate Kathon 893 MW compatibility in use-dilution or concentrate metalworking fluids prior to commercialization. Kathon 893 MW is compatible with most other metalworking fluid biocides, including KATHON 886 MW and KATHON CC (methylchlorosiothiazolone), KORDEK™ LX5000 (methylisothiazolone), ROCIMA™ BT 2S biocides (benzisothiazolone), triazine and formaldehyde-releasers, IPBC (iodopropynylbutylcarbamate) and sodium Pyrithione. Stability In-Use Stability: Kathon 893 MW Biocide has excellent stability in end use dilutions of metalworking fluids. It is stable over a wide pH range (4-10) in water and in metalworking fluid systems. Concentrate Stability: Kathon 893 MW Biocide stability, in metalworking fluid concentrates, is variable. We recommend checking stability and performance before commercialization of products. Dow has several recommended stabilizers to improve stability and compatibility in many types of concentrates. Storage Stability: In general, the storage stability of the Kathon 893 MW Biocide product is excellent. The shelf life of the product is nominally twelve years at 25°C. It is strongly recommended, however, that both the stability and compatibility of Kathon 893 MW Biocide in metalworking fluid formulations or systems be thoroughly examined before commercialization. Method of Addition Kathon 893 MW Biocide should be directly dispensed into metalworking fluid concentrates or use-dilution metalworking fluids using a metering pump or other point-of-use device where possible and uniformLy dispersed throughout the fluid. Fluid Concentrate Kathon 893 MW Biocide should be added to metalworking fluid concentrates at a level that ensures the final use-dilution fluid will contain 55 to 167 ppm of product (25 to 75 ppm active ingredient). Kathon 893 MW stability in a given concentrate should be determined prior to commercialization. Contact your local Dow representative for assistance in selecting one of several recommended stabilizers to enhance the performance and compatibility of Kathon 893 MW in your metalworking fluid concentrate. Use-Dilution Fluid We highly recommend grossly contaminated systems be cleaned before treatment is begun. Initial Dose: For a noticeably fouled system, add 0.47 to 1.44 lbs (7 to 21 fl oz) of Kathon 893 MW Biocide per 1,000 gallons of fluid. This will provide 25 to 75 ppm active ingredient. Repeat until control is achieved. Subsequent Dose: For maintenance of a non-fouled system, add 0.09 to 0.58 lbs (1.3 to 8.6 fl oz) of Kathon 893 MW Biocide per 1,000 gallons of fluid every four weeks. This will provide 5 to 30 ppm active ingredient. A higher dose range and/or increased frequency of treatment may be required, depending upon the rate of dilution of the preservative with the makeup fluid, the nature and severity of contamination, level of control required, filtration effectiveness, system design, etc. General Practices When Using Kathon 893 Biocides • Know the size of your system and dose at the recommended use levels. • To improve performance and longevity, add Kathon 893 MW Biocide on the clean side of the filters. It may be necessary to occasionally add Kathon 893 MW to the dirty side of the filters if large populations of microorganisms are detected there. • Minimize contamination: – Eliminate or minimize dead spots – Disconnect unused portions of the system – Do not throw trash in sumps • Always remember to triple rinse (or equivalent) empty containers to avoid incidental contact. • Post placard with safety information and deactivation protocol near biocide handling area. Additional guidelines for maximizing the performance of Kathon 893 MW Biocide are as follows: • Kathon 893 MW stability and performance is improved with lower pH. Whenever possible, maintain the pH of system below pH 9.2. Lower pH also makes amines and amine-containing compounds less aggressive. • For systems with pH greater than 9.5, we strongly recommend determination of biological efficacy and chemical stability prior to use. • Avoid adding highly basic additives (alkaline materials with pH of 10-12) immediately prior to or after adding Kathon 893 MW to your system. If a highly basic additive must be added, allow sufficient time (at least 30 minutes) between additions. Minimize levels of diethanolamine (DEA) in your system. If possible use 99% triethanolamine (TEA) or monoethanolamine (MEA) instead of DEA, and use these at as low a level as possible. • Always add Kathon 893 MW directly to the metalworking fluid sump. Never use Kathon 893 MW in a spray bottle. • Avoid charging Kathon 893 MW in high temperature zones, since increasing temperatures accelerate other degradation effects. Ideally, add Kathon 893 MW to the fluid below 60°C (140°F). • Avoid adding Kathon 893 MW and incompatible corrosion inhibitors directly to the tank at the same time. How Does Kathon 893 MW Biocide Work? Kathon 893 MW Biocide utilizes a two-step mechanism involving rapid growth inhibition leading to a loss of cell viability. Growth inhibition is the result of rapid disruption of the central metabolic pathways of the cell by inhibition of several specific enzymes, including dehydrogenases. The critical enzymes which are affected are associated with the Krebs cycle, nutrient metabolism and energy generation. The key physiological activities that are rapidly inhibited in microbial cells are respiration (oxygen consumption), energy generation (ATP synthesis), and growth (assimilation). Many of these key enzymes are present in both aerobic and anaerobic microorganisms, which explains why Kathon 893 MW is such a broad spectrum biocide. Inhibition of cellular activity and growth is rapid (within minutes), whereas cell death (cidal activity) is observed after several hours’ contact. In general, the higher the concentration of biocide, the shorter the contact time required for more complete kill. Cell death results from the progressive loss of protein thiols in the cell from one of multiple pathways. As cell metabolism is disrupted, free radicals are produced which also results in cell death. This unique mechanism results in the broad spectrum of activity of Kathon 893 MW Biocide, low use levels for microbial control, and difficulty in attaining resistance by mutation. See technical bulletin (CS-632) for more detailed information. How Rapidly Does Kathon 893 MW Biocide Work? Within minutes after addition of Kathon 893 MW Biocide to a metalworking fluid sump, the metabolic activity of the microorganisms in the system shuts down. This includes cellular respiration (oxygen uptake), growth, energy generation, and nutrient uptake. The microorganisms, although still alive, are no longer able to reproduce or metabolize metalworking fluid components. After 24 to 48 hours of contact with a lethal dose of the biocide, most of the microorganisms have been killed. How Long Does Kathon 893 MW Biocide Last? Kathon 893 MW Biocide has excellent in-use stability and generally retains its antimicrobial efficacy in metalworking fluid systems for 2 to 4 weeks. Variables such as degree of fluid contamination, effectiveness of the filtration system, system turnover time, compatibility between the microbicide and the metalworking fluid components, and other system additives involved, can affect the life of the microbicide in a system. Is Kathon 893 MW Biocide Effective in Reducing Fungal Biofilms? YES. Kathon 893 MW Biocide has been shown to reduce microbial fouling and prevent biofilm development in metalworking fluid systems. The benefits of reduced fungal biofouling include improved system performance, reduced filter plugging, reduced biocorrosion, and improved microbial control. Is Kathon 893 MW Biocide Effective When Used in Concentrates? YES. Kathon 893 MW Biocide may be used in certain fluid concentrates to provide efficacy in the final use dilutions. Although Kathon 893 MW stability may not be suitable for all concentrates, we have had success with the biocide alone or in combination with one of our recommended stabilizers. How Can I Improve Kathon 893 MW Biocide Stability in Concentrates? We recommend testing Kathon 893 MW Biocide in concentrates prior to commercialization. Dow technical staff can assist you in formulating products. We have years of experience and a range of recommended stabilizers to prolong the lifetime and improve compatibility of Kathon 893 MW in concentrates. Contact your sales representative for assistance. Anti-Microbial Properties of Kathon 893 MW Biocide Initial determinations of the efficacy of any biocidal product are made via minimum inhibitory concentration (MIC) measurements. The MIC test yields valuable information about the product’s inherent antimicrobial efficacy and spectrum of activity. The MIC for any product is the lowest level at which the active ingredient inhibits the growth of various microorganisms. This method is a useful tool for screening antimicrobial agents under standardized laboratory conditions, in nutrient-rich growth conditions. In interpreting the data, remember that low values correspond to high activity. Table 2 indicates that Kathon 893 MW Biocide possesses outstanding antimicrobial activity against a broad range of fungi (both yeasts and molds). Kathon 893 MW has very low MIC values for most of the fungi tested and there is no gap in the spectrum of activity among the organisms tested. Kathon 893 MW Biocide was evaluated as a tankside fungicide in a wide variety of metalworking fluids, including synthetics, semi-synthetics, and soluble-oil fluids. In a oneweek eradication study described below, a total of 16 fluids from various manufacturers in the United States, Europe, and Japan were tested. Test Procedure The actual test systems were run in volumes of 50 mL, which consisted of 40 mL of virgin metalworking fluid (generally diluted 20:1) and 10 mL of the adapted inoculum as described above. Prior to inoculation, the fluids containing fungal growth were blended for two minutes at high speed in a Waring blender. Most samples contained 0.5 g of iron filings. At time zero, the following active levels of Kathon 893 MW Biocide were added: 5 ppm, 10 ppm, 25 ppm, 50 ppm, 75 ppm, and 100 ppm. Additionally, samples were run containing 50 ppm and 100 ppm active sodium Pyrithione. Once fluids were dosed with biocide and inoculated, they were mechanically shaken for one week and plated on sabouraud dextrose agar. Results Kathon 893 MW Biocide was completely effective in all fluids at levels ranging from 5 to 75 ppm active ingredient. In all but one of the fluids, it was effective at concentrations in the range of 5 to 50 ppm active ingredient. In synthetic fluids, which are prone to fungal growth, Kathon 893 MW was effective in the range of 5 to 10 ppm. Sodium Pyrithione was not very effective at recommended use levels of 50 to 100 ppm active ingredient. A long-term study was done to compare the fungicidal activity of Kathon 893 MW Biocide and sodium Pyrithione in a synthetic metalworking fluid, use-dilution 1:30. The concentration of Kathon 893 MW studied ranged from 10 to 75 ppm active ingredient and the concentration of sodium pyrithione ranged from 50 to 200 ppm active ingredient. Test Procedure The test samples were inoculated at zero time and again every two weeks with fungal inoculum isolated from naturally contaminated synthetic metalworking fluid and maintained in the same fluid employed in the test. Results Results, provided in Table 4, show that particularly high fungal counts were not achieved in the untreated control for this particular fluid (note: Due to the inherent mycelial clumping common to most fungal species when growing in liquid substrates, plate counts of colonyforming units carried out on the aliquots of the liquid are not always indicative of the degree of fungal contamination present). In spite of this, sodium Pyrithione allowed fungal survival at all levels at which it was tested. Kathon 893 MW Biocide, however, exhibited complete fungal control at significantly lower levels. There is usually a need to control both bacteria and fungi in metalworking fluid systems. Bacteria and fungi, however, are not always controlled by one biocide. For example, Kathon 893 886 MW Biocide is a broad-spectrum biocide that controls the growth of bacteria and fungi, including molds and yeast, in many metalworking fluid systems and therefore can usually be used alone. Some fluids, however, contain aggressive components which may decrease the stability of KATHON 886 MW and therefore reduce its efficacy for controlling microorganisms. If such fluids are especially prone to fungal growth, use of KATHON 893 MW in conjunction with KATHON 886 MW, KORDEK™ LX5000, or ROCIMA™ BT 2S biocides is recommended. These products are completely compatible and provide excellent cost performance. Kathon 893 MW is also compatible with other bactericides, including triazine and formaldehyde releasers, and other fungicides. The use of Kathon 893 MW in the same system as KATHON 886 MW, KORDEK LX5000, and a number of other biocides are covered in several Dow patents. The efficacy of Kathon 893 MW Biocide in a use-dilution synthetic metalworking fluid was evaluated under actual use conditions during a five-month field trial in a 200,000-gallon system. At the start of the trial, fungal mats covered the walls of the flumes and weirs of the system and filters which required constant maintenance to prevent clogging (see Figure 1). Fungal slime was also present on and around many of the machines supplied by the system. The bacterial population of the fluid was between 103 and 104 cfu/mL (colonyforming units per mL), and the fungal population was between 380 and 790 cfu/mL. During the first 45 days of the trial, the level of Kathon 893 MW Biocide was maintained at approximately 25 ppm active ingredient. For the remaining 3 months of the trial, the level of Kathon 893 MW was maintained between 30 ppm and 10 ppm active ingredient. The results of the trial showed that the regimen of Kathon 893 MW addition chosen provided essentially complete control of fungal organisms in the fluid itself and also destroyed the fungal organisms comprising the mats covering the walls of the flumes and weirs of the system. These fungal mats lost their integrity and gradually sloughed off the surfaces to which they were attached (see Figure 2). The microbial slime present on and around the machines also disappeared. The bacterial populations of the fluid remained in the range of 102 to 104 cfu/mL, throughout the trial. In addition, the amount of makeup fluid required to maintain the desired characteristics of the fluid was reduced significantly (42 percent) during the trial. Handling The procedures used for handling concentrated biocide solutions are similar to those used for handling concentrated acids and alkalis. The purpose is to prevent all eye and skin contact, including inhalation of mists, and thereby prevent possible injury and sensitization. Personnel handling Kathon 893 MW Biocide as supplied should always wear protective clothing, which includes chemical splash goggles, an impervious apron or rain suit, and impervious rubber gloves. We recommend that employees working with Kathon 893 MW as supplied thoroughly wash with soap and water at the end of a shift or prior to eating, drinking, smoking, or applying cosmetics. Special care should be taken to avoid contamination of surfaces or materials that may later be handled by unprotected personnel, for example, door and tap handles. Storage Kathon 893 MW Biocide is packaged in polyethylene or polyethylene-lined containers. It should not be stored in unlined metal containers since it is a corrosive material. Normal recommended storage temperatures are in the range of 10° to 25°C (50° to 80°F). Shelf life ~12 years (packaging should be evaluated and replaced as needed for transport compliance over the duration of product shelf life). Storage at >120°F for extended periods of time can result in degradation of the active ingredient. Decontamination Solutions Kathon 893 MW Biocide can be decontaminated with a 5% solution of sodium hypochlorite (NaOCl) containing 2-5% sodium bicarbonate (NaHCO3 ). Solutions should be freshly prepared. Employees preparing or handling decontamination solutions should wear chemical splash goggles, an impervious apron or rain suit, and impervious rubber gloves. Note: Do not use decontamination solution to treat skin, eyes or clothing which have come in contact with Kathon 893 MW. Decontamination of Equipment Equipment used in the handling of Kathon 893 MW Biocide, such as mix tanks, lines, pumps, etc., must be decontaminated before carrying out maintenance or used for other service. To decontaminate this equipment, estimate the volume of Kathon 893 MW remaining in the well-drained system. Prepare 10 volumes of decontamination solution per volume of Kathon 893 MW (45%) and circulate the mixture throughout the equipment. Be certain that the Kathon 893 MW and decontamination solution mix well. Wait at least 30 minutes to ensure complete reaction. Drain and rinse with clean water or detergent solution. Decontamination solution runoffs should be drained to a chemical sewer unless prohibited by state or local regulations. Drips, minor spills and exposed wet areas should be cleaned up promptly with the hypochlorite/bicarbonate mixture. Contaminated surfaces should be swabbed with decontamination solution and allowed to stand for 30 minutes before rinsing thoroughly with water. Decontaminated solutions should be drained to a chemical sewer unless prohibited by state or local regulations. Note: Because of the high level of activity of Kathon 893 MW, a relatively small quantity could have a damaging impact on the effectiveness of waste treatment bio-systems. Laboratory or plant spills should be decontaminated with decontamination solution before being released to a biological waste treatment system. Cleanup of Spills Procedures provided in the Safe Handling Section should be followed when cleaning spills of Kathon 893 MW Biocide. 1. Wear impervious rubber gloves, chemical splash goggles, protective clothing and overshoes. 2. Dike and adsorb the spilled material on an inert solid, such as clay or vermiculite or with spill control pillows. 3. Transfer the adsorbent or pillows and surrounding surface soil into a pail or drum. This container should be no more than two-thirds full. 4. Treat the contents of the container with 10 volumes of decontamination solution per estimated volume of spilled Kathon 893 MW. 5. Treat the surrounding spill area with excess decontamination solution. Flush after a minimum of 30 minutes into a chemical sewer. 6. Do not discharge spills and cleaning runoffs into open bodies of water, because of a potential adverse impact on the environment. 7. Carefully remove the contaminated gloves and place them in the container (peel off the gloves by pulling on the outside of the glove sleeve turning them inside out as they are removed). After 48 hours, seal the container and dispose of it by landfilling in accordance with local, state, and federal regulations. Bulletin CS-561, which is available on request, contains methods for determining the presence of Kathon 893 MW Biocide’s active ingredient in use dilution metalworking fluids by high performance liquid chromatography (HPLC). This bulletin also contains HPLC procedures for determining KATHON 886 MW active ingredients in use-dilution metalworking fluids. Dow maintains Safety Data Sheets (SDS) for all of its products. These sheets contain pertinent information that you may need to protect your employees and customers against any known health or safety hazards associated with our products.We recommend that you obtain and review Safety Data Sheets (SDS) for our products from your distributor or Dow technical representative before using our products in your facility. We also suggest that you contact your supplier of other materials recommended for use with our product for appropriate health and safety precautions before using them. Dow Sales Service and Technical Service departments have over twenty-five years’ experience evaluating Kathon 893 biocides’ performance in a variety of applications. In the area of metalworking fluids we can advise on determining KATHON biocide stability and efficacy in use-dilution as well as concentrate metalworking fluids, and we can make recommendations on how to evaluate the level and type of system contamination you may be experiencing. In addition, Dow personnel can assist you with questions on KATHON biocides’ toxicology, environmental issues, safe storage, handling and use. Finally, Dow has available for your use a videotape on the safe use and handling of the family of KATHON and KORDEK™ biocides for the metalworking industry, including Kathon 893 MW, KATHON 886 MW and KORDEK LX5000 biocides. For further information, contact your local Dow KATHON biocide representative or contact Dow. Kathon 893 MW Biocide 45% solution is available in 5-gallon pails (44 lbs), 30-gallon drums (44 lbs), and cartons (22 lbs) containing two 1-gallon jugs. To obtain samples, technical assistance, a Safety Data Sheet (SDS), or to have a technical representative call for an appointment, contact the nearest Dow office. Kathon 893 MW Biocide is a biocidal product intended for use in accordance with Product Type 13 (Metalworking fluid preservatives) of the Biocidal Products Directive 98/8/ EC (BPD). Dow has a fundamental concern for all who make, distribute, and use its products, and for the environment in which we live. This concern is the basis for our product stewardship philosophy by which we assess the safety, health, and environmental information on our products and then take appropriate steps to protect employee and public health and our environment. The success of our product stewardship program rests with each and every individual involved with Dow products – from the initial concept and research, to manufacture, use, sale, disposal, and recycle of each product.
KATHON 893 MW
KATHON 893 MW Biocide Metalworking Fluid Fungicide for Water-Based Cutting Fluids EPA Reg. No.: 707-195 Soluble, synthetic, and semi-synthetic metalworking fluids or coolants provide an excellent environment for the growth of various microorganisms, including bacteria, mold, and yeast. If allowed to grow, these organisms can have detrimental effects on the fluids. For example, bacteria, which can grow very quickly, can destroy the integrity of the fluid by discoloration, destroying lubricity characteristics, and causing emulsions to split. Bacteria can also reduce the pH of the fluid, which can promote corrosion. Some forms of bacteria have objectionable odors. Fungi typically grow more slowly than bacteria, but can form large masses which clog filters and lines and in some cases lead to system shutdown; fungi also generate foul odors and can cause corrosion. The increased use of synthetic fluids over the past few years has led to an even greater need for the enhanced fungal control that KATHON 893 MW Biocide can provide. For Tankside and Concentrate KATHON 893 MW Biocide is a broad-spectrum fungicide that has been recommended and widely used for tankside control of fungi in metalworking central systems. KATHON 893 MW is also an effective fungicide for use in many metalworking fluid concentrates with the appropriate stabilizer package. Due to the wide variations in metalworking fluid formulations, laboratory or small-scale tests are recommended to evaluate KATHON 893 MW in usedilution and concentrate metalworking fluids before they are commercialized. KATHON 893 MW is a highly effective, industrial fungicide that exhibits excellent fungistatic and fungicidal activity against fungi, including yeasts and mold, and Gram-Positive bacteria, and limited activity against Gram-Negative bacteria. Commonly known as octhilinone, 2-n-octyl-4-isothiazolin-3-one is the active ingredient of KATHON 893 MW. It is supplied as a 45 percent active liquid in propylene glycol. The information in this brochure has been compiled to familiarize the reader with KATHON 893 MW technology, to communicate the tremendous benefits of this product, and to provide directions for safe and efficient use of the product. By following the precautions outlined in this brochure, on the product label, and on the Dow Safety Data Sheet (SDS), KATHON 893 MW can be safely handled. H O C3H8 -n C C N S C H 2-n-octyl-4-isothiazolin-3-one 45% minimum Propylene glycol (inert) 50% minimum The following are typical properties of KATHON 893 MW Biocide; they are not to be considered product specifications. Appearance: Yellow to amber liquid Color (VCS): 8 max. Mildly sweet Specific gravity @ 24°C: 1.03 Flash point, °C (Pensky Martens Closed Cup): 93 Viscosity Brookfield @ 20°C, cps: 40 Melting point, °C: -40 Boiling point, °C: 188 Vapor pressure, active ingredient @ 25°C: 3.7 x 10-5 torr Solubility The solubility data provided below were determined at ambient temperatures (20 to 25°C). The solubility and stability of the active ingredient may be affected when the temperature is lowered to 0°C or increased to 60°C. • KATHON 893 MW Biocide is soluble in methanol, ethanol, propylene glycol, acetone, ethyl ether, ethyl acetate, chloroform, butyl Cellosolve, corn oil, and mineral oil. • The solubility of KATHON 893 MW in toluene is 25% w/v. • The solubility of KATHON 893 MW in water at 25°C is 480 ppm (active ingredient), although this may be increased by using suitable surfactants and emulsifiers. • KATHON 893 MW is insoluble in heptane. Compatibility In concentrate and use-dilution metalworking fluids, the compatibility of KATHON 893 MW Biocide is concentration-dependent and varies from formulation to formulation. It is compatible with most metalworking fluid additives, including surfactants and amines. Compatibility with amines may vary by the type, concentration and pH. Strong reducing agents, such as sulfides, mercaptans, bisulfites and metabisulfites, or strong oxidizing agents, such as hypochlorites, may affect the efficacy of KATHON 893 MW. Laboratory or small-scale tests are recommended in order to evaluate KATHON 893 MW compatibility in use-dilution or concentrate metalworking fluids prior to commercialization. KATHON 893 MW is compatible with most other metalworking fluid biocides, including KATHON 886 MW and KATHON CC (methylchlorosiothiazolone), KORDEK LX5000 (methylisothiazolone), ROCIMA BT 2S biocides (benzisothiazolone), triazine and formaldehyde-releasers, IPBC (iodopropynylbutylcarbamate) and sodium Pyrithione. Stability In-Use Stability: KATHON 893 MW Biocide has excellent stability in end use dilutions of metalworking fluids. It is stable over a wide pH range (4-10) in water and in metalworking fluid systems. Concentrate Stability: KATHON 893 MW Biocide stability, in metalworking fluid concentrates, is variable. We recommend checking stability and performance before commercialization of products. Dow has several recommended stabilizers to improve stability and compatibility in many types of concentrates. Storage Stability: In general, the storage stability of the KATHON 893 MW Biocide product is excellent. The shelf life of the product is nominally twelve years at 25°C. It is Physical Properties PS strongly recommended, however, that both the stability and compatibility of KATHON 893 MW Biocide in metalworking fluid formulations or systems be thoroughly examined before commercialization. Table 1 The many advantages of protecting your metalworking fluids with KATHON 893 MW Biocide fungicide include: Features Benefits Highly effective microbicide Extends metalworking fluid life, reduces downtime, reduces makeup fluid use and reduces fluid disposal costs Broad spectrum activity Kills fungi and prevents the return of slime caused by fungal microorganisms, eliminates clogged lines and filters and musty odors caused by fungi Patented combinations of KATHON 886 MW or KORDEK LX5000 biocides with KATHON 893 MW Biocide Synergistic combinations that enhance the already wide spectrum of bioactivity. Enhanced activity present even if KATHON 893 MW is added in the concentrate and KATHON 886 MW added tankside Good temperature and pH stability Works well in a variety of metalworking conditions up to 60°C (140°F) and pH 10 Highly soluble in water and does not foam Easy to dose Provides long lasting fungal control Cost effective versus competitive tankside treatments Fast acting Quickly controls growth and activity of odor-causing fungi Effective at low use rates and biodegradable Better for the environment Does not contain, release or generate formaldehyde Not subject to concern about formaldehyde, a known carcinogen Method of Addition KATHON 893 MW Biocide should be directly dispensed into metalworking fluid concentrates or use-dilution metalworking fluids using a metering pump or other point-of-use device where possible and uniformLy dispersed throughout the fluid. Fluid Concentrate KATHON 893 MW Biocide should be added to metalworking fluid concentrates at a level that ensures the final use-dilution fluid will contain 55 to 167 ppm of product (25 to 75 ppm active ingredient). KATHON 893 MW stability in a given concentrate should be determined prior to commercialization. Contact your local Dow representative for assistance in selecting one of several recommended stabilizers to enhance the performance and compatibility of KATHON 893 MW in your metalworking fluid concentrate. Use-Dilution Fluid We highly recommend grossly contaminated systems be cleaned before treatment is begun. Initial Dose: For a noticeably fouled system, add 0.47 to 1.44 lbs (7 to 21 fl oz) of KATHON 893 MW Biocide per 1,000 gallons of fluid. This will provide 25 to 75 ppm active ingredient. Repeat until control is achieved. Subsequent Dose: For maintenance of a non-fouled system, add 0.09 to 0.58 lbs (1.3 to 8.6 fl oz) of KATHON 893 MW Biocide per 1,000 gallons of fluid every four weeks. This will provide 5 to 30 ppm active ingredient. A higher dose range and/or increased frequency of treatment may be required, depending upon the rate of dilution of the preservative with the makeup fluid, the nature and severity of contamination, level of control required, filtration effectiveness, system design, etc. Key Features & Benefits Applications/ Directions for Use General Practices When Using KATHON Biocides • Know the size of your system and dose at the recommended use levels. • To improve performance and longevity, add KATHON 893 MW Biocide on the clean side of the filters. It may be necessary to occasionally add KATHON 893 MW to the dirty side of the filters if large populations of microorganisms are detected there. • Minimize contamination: – Eliminate or minimize dead spots – Disconnect unused portions of the system – Do not throw trash in sumps • Always remember to triple rinse (or equivalent) empty containers to avoid incidental contact. • Post placard with safety information and deactivation protocol near biocide handling area. Additional guidelines for maximizing the performance of KATHON 893 MW Biocide are as follows: • KATHON 893 MW stability and performance is improved with lower pH. Whenever possible, maintain the pH of system below pH 9.2. Lower pH also makes amines and amine-containing compounds less aggressive. • For systems with pH greater than 9.5, we strongly recommend determination of biological efficacy and chemical stability prior to use. • Avoid adding highly basic additives (alkaline materials with pH of 10-12) immediately prior to or after adding KATHON 893 MW to your system. If a highly basic additive must be added, allow sufficient time (at least 30 minutes) between additions. Minimize levels of diethanolamine (DEA) in your system. If possible use 99% triethanolamine (TEA) or monoethanolamine (MEA) instead of DEA, and use these at as low a level as possible. • Always add KATHON 893 MW directly to the metalworking fluid sump. Never use KATHON 893 MW in a spray bottle. • Avoid charging KATHON 893 MW in high temperature zones, since increasing temperatures accelerate other degradation effects. Ideally, add KATHON 893 MW to the fluid below 60°C (140°F). • Avoid adding KATHON 893 MW and incompatible corrosion inhibitors directly to the tank at the same time. How Does KATHON 893 MW Biocide Work? KATHON 893 MW Biocide utilizes a two-step mechanism involving rapid growth inhibition leading to a loss of cell viability. Growth inhibition is the result of rapid disruption of the central metabolic pathways of the cell by inhibition of several specific enzymes, including dehydrogenases. The critical enzymes which are affected are associated with the Krebs cycle, nutrient metabolism and energy generation. The key physiological activities that are rapidly inhibited in microbial cells are respiration (oxygen consumption), energy generation (ATP synthesis), and growth (assimilation). Many of these key enzymes are present in both aerobic and anaerobic microorganisms, which explains why KATHON 893 MW is such a broad spectrum biocide. Inhibition of cellular activity and growth is rapid (within minutes), whereas cell death (cidal activity) is observed after several hours’ contact. In general, the higher the concentration of biocide, the shorter the contact time required for more complete kill. Cell death results from the progressive loss of protein thiols in the cell from one of multiple pathways. As cell metabolism is disrupted, free radicals are produced which also results in cell death. This unique mechanism results in the broad spectrum of activity of KATHON 893 MW Biocide, low use levels for microbial control, and difficulty in attaining resistance by mutation. See technical bulletin (CS-632) for more detailed information. How Rapidly Does KATHON 893 MW Biocide Work? Within minutes after addition of KATHON 893 MW Biocide to a metalworking fluid sump, the metabolic activity of the microorganisms in the system shuts down. This includes cellular respiration (oxygen uptake), growth, energy generation, and nutrient uptake. The microorganisms, although still alive, are no longer able to reproduce or metabolize metalworking fluid components. After 24 to 48 hours of contact with a lethal dose of the biocide, most of the microorganisms have been killed. How Long Does KATHON 893 MW Biocide Last? KATHON 893 MW Biocide has excellent in-use stability and generally retains its antimicrobial efficacy in metalworking fluid systems for 2 to 4 weeks. Variables such as degree of fluid contamination, effectiveness of the filtration system, system turnover time, compatibility between the microbicide and the metalworking fluid components, and other system additives involved, can affect the life of the microbicide in a system. Is KATHON 893 MW Biocide Effective in Reducing Fungal Biofilms? YES. KATHON 893 MW Biocide has been shown to reduce microbial fouling and prevent biofilm development in metalworking fluid systems. The benefits of reduced fungal biofouling include improved system performance, reduced filter plugging, reduced biocorrosion, and improved microbial control. Is KATHON 893 MW Biocide Effective When Used in Concentrates? YES. KATHON 893 MW Biocide may be used in certain fluid concentrates to provide efficacy in the final use dilutions. Although KATHON 893 MW stability may not be suitable for all concentrates, we have had success with the biocide alone or in combination with one of our recommended stabilizers. How Can I Improve KATHON 893 MW Biocide Stability in Concentrates? We recommend testing KATHON 893 MW Biocide in concentrates prior to commercialization. Dow technical staff can assist you in formulating products. We have years of experience and a range of recommended stabilizers to prolong the lifetime and improve compatibility of KATHON 893 MW in concentrates. Contact your sales representative for assistance. Anti-Microbial Properties of KATHON 893 MW Biocide Initial determinations of the efficacy of any biocidal product are made via minimum inhibitory concentration (MIC) measurements. The MIC test yields valuable information about the product’s inherent antimicrobial efficacy and spectrum of activity. The MIC for any product is the lowest level at which the active ingredient inhibits the growth of various microorganisms. This method is a useful tool for screening antimicrobial agents Efficacy Data Page under standardized laboratory conditions, in nutrient-rich growth conditions. In interpreting the data, remember that low values correspond to high activity. Table 2 indicates that KATHON 893 MW Biocide possesses outstanding antimicrobial activity against a broad range of fungi (both yeasts and molds). KATHON 893 MW has very low MIC values for most of the fungi tested and there is no gap in the spectrum of activity among the organisms tested. Table 2 Fungistatic Activity of KATHON 893 MW Biocide Organism ATCC Number (Strain) MIC* in PPM Active Ingredient Alternaria dianthicola 11782 1 Aspergillus niger 9642 8 Aspergillus oryzae 10196 2 Aspergillus repens 9294 2 Aureobasidium pullulans 9348 0.3 Candida albicans (yeast) 11651 2 Chaetomium globosum 6205 4 Cladosporium resinae 11274 0.5 Lenzites lepideus 12653 2 Lenzites trabea 11539 2 Penicillium funiculosum 9644 1 Phoma glomerata 6735 120°F for extended periods of time can result in degradation of the active ingredient. Store away from direct sunlight. Decontamination and Spill Procedures Decontamination Solutions KATHON 893 MW Biocide can be decontaminated with a 5% solution of sodium hypochlorite (NaOCl) containing 2-5% sodium bicarbonate (NaHCO3 ). Solutions should be freshly prepared. Employees preparing or handling decontamination solutions should wear chemical splash goggles, an impervious apron or rain suit, and impervious rubber gloves. Note: Do not use decontamination solution to treat skin, eyes or clothing which have come in contact with KATHON 893 MW. Decontamination of Equipment Equipment used in the handling of KATHON 893 MW Biocide, such as mix tanks, lines, pumps, etc., must be decontaminated before carrying out maintenance or used for other service. To decontaminate this equipment, estimate the volume of KATHON 893 MW remaining in the well-drained system. Prepare 10 volumes of decontamination solution per volume of KATHON 893 MW (45%) and circulate the mixture throughout the equipment. Be certain that the KATHON 893 MW and decontamination solution mix well. Wait at least 30 minutes to ensure complete reaction. Drain and rinse with clean water or detergent solution. Decontamination solution runoffs should be drained to a chemical sewer unless prohibited by state or local regulations. Drips, minor spills and exposed wet areas should be cleaned up promptly with the hypochlorite/bicarbonate mixture. Contaminated surfaces should be swabbed with decontamination solution and allowed to stand for 30 minutes before rinsing thoroughly with water. Decontaminated solutions should be drained to a chemical sewer unless prohibited by state or local regulations. Note: Because of the high level of activity of KATHON 893 MW, a relatively small quantity could have a damaging impact on the effectiveness of waste treatment bio-systems. Laboratory or plant spills should be decontaminated with decontamination solution before being released to a biological waste treatment system. Cleanup of Spills Procedures provided in the Safe Handling Section should be followed when cleaning spills of KATHON 893 MW Biocide. 1. Wear impervious rubber gloves, chemical splash goggles, protective clothing and overshoes. 2. Dike and adsorb the spilled material on an inert solid, such as clay or vermiculite or with spill control pillows. 3. Transfer the adsorbent or pillows and surrounding surface soil into a pail or drum. This container should be no more than two-thirds full. 4. Treat the contents of the container with 10 volumes of decontamination solution per estimated volume of spilled KATHON 893 MW. 5. Treat the surrounding spill area with excess decontamination solution. Flush after a minimum of 30 minutes into a chemical sewer. 6. Do not discharge spills and cleaning runoffs into open bodies of water, because of a potential adverse impact on the environment. 7. Carefully remove the contaminated gloves and place them in the container (peel off the gloves by pulling on the outside of the glove sleeve turning them inside out as they are removed). After 48 hours, seal the container and dispose of it by landfilling in accordance with local, state, and federal regulations. Safety Data Sheets Dow Technical Support Shipping Information Biocidal Product Directive Compliance Product Stewardship Bulletin CS-561, which is available on request, contains methods for determining the presence of KATHON 893 MW Biocide’s active ingredient in use dilution metalworking fluids by high performance liquid chromatography (HPLC). This bulletin also contains HPLC procedures for determining KATHON 886 MW active ingredients in use-dilution metalworking fluids. Dow maintains Safety Data Sheets (SDS) for all of its products. These sheets contain pertinent information that you may need to protect your employees and customers against any known health or safety hazards associated with our products. We recommend that you obtain and review Safety Data Sheets (SDS) for our products from your distributor or Dow technical representative before using our products in your facility. We also suggest that you contact your supplier of other materials recommended for use with our product for appropriate health and safety precautions before using them. Dow Sales Service and Technical Service departments have over twenty-five years’ experience evaluating KATHON biocides’ performance in a variety of applications. In the area of metalworking fluids we can advise on determining KATHON biocide stability and efficacy in use-dilution as well as concentrate metalworking fluids, and we can make recommendations on how to evaluate the level and type of system contamination you may be experiencing. In addition, Dow personnel can assist you with questions on KATHON biocides’ toxicology, environmental issues, safe storage, handling and use. Finally, Dow has available for your use a videotape on the safe use and handling of the family of KATHON and KORDEK biocides for the metalworking industry, including KATHON 893 MW, KATHON 886 MW and KORDEK LX5000 biocides. For further information, contact your local Dow KATHON biocide representative or contact Dow. KATHON 893 MW Biocide 45% solution is available in 5-gallon pails (44 lbs), 30-gallon drums (44 lbs), and cartons (22 lbs) containing two 1-gallon jugs. To obtain samples, technical assistance, a Safety Data Sheet (SDS), or to have a technical representative call for an appointment, contact the nearest Dow office. KATHON 893 MW Biocide is a biocidal product intended for use in accordance with Product Type 13 (Metalworking fluid preservatives) of the Biocidal Products Directive 98/8/ EC (BPD). Dow has a fundamental concern for all who make, distribute, and use its products, and for the environment in which we live. This concern is the basis for our product stewardship philosophy by which we assess the safety, health, and environmental information on our products and then take appropriate steps to protect employee and public health and our environment. The success of our product stewardship program rests with each and every individual involved with Dow products – from the initial concept and research, to manufacture, use, sale, disposal, and recycle of each product.
KERATIN
HYDROLYZED KERATIN, N° CAS : 69430-36-0 - Kératine hydrolysée. Autres langues : Cheratina idrolizzata, Hydrolysiertes Keratin, Queratina hidrolizada. Nom INCI : HYDROLYZED KERATIN N° EINECS/ELINCS : 274-001-1, La kératine est une protéine fibreuse qui se trouve dans les cheveux, les plumes, la laine et les ongles. Cette protéine utilisée en cosmétique est d'origine animale et provient le plus souvent de la laine de mouton. La version végétale de la kératine se nomme Phytokératine et est plus connue dans la liste INCI sous le terme : "HYDROLYZED WHEAT PROTEIN".Dans les cosmétiques, la kératine est utilisée pour lisser et hydrater la cuticule des cheveux endommagés. Elle permet de combler les fissures et élimine les frisottis liés au dessèchement.Ses fonctions (INCI) Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Agent filmogène : Produit un film continu sur la peau, les cheveux ou les ongles Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau Agent d'entretien de la peau : Maintient la peau en bon état
KERATIN
Keratin is a group of proteins that form 10 nm intermediate filaments in all epithelial cells covering the inner and outer surfaces of the body, are insoluble in water and play an important role in hair, nail or skin care.
Keratin is a member of the scleroprotein family of fibrous structural proteins.


CAS 68238-35-7


Keratin oil frequently helps to shield epithelial cells from harm and stress.
In both water and organic solvents, keratin is highly insoluble.
Keratin monomers package into intermediate filaments that are durable and form heavy unmineralized epidermal appendages in birds, reptiles, mammals and amphibians.


Keratin is a member of the scleroprotein family of fibrous structural proteins.
In vertebrates, keratin is a form of keratin.
Scales, horns, fur, feathers, nails, paws, calluses, hooves, and the external layer of the skin are all made of Keratin.


Keratin is a type of protein found in our teeth, nails and hair, making your hair look smooth, vibrant and full.
The flexible structure of our hair is protected thanks to keratin.
Put an end to the tangle after the shower and the frizz that occurs during the day.


Keratin is used in more than 7,000 hair salons in Turkey and is the keratin care product with the highest satisfaction rate.
Keratin is a type of fibrous, acidic or basic protein found in epithelial cells covering the inner and outer surfaces of the body and in tissues such as hair and nails.


Keratin, which has 54 types in the body, helps support the skin, heal wounds, and keep nails and hair healthy.
In addition to being produced naturally in the body, you can also meet the body's keratin needs by using keratin care products or consuming keratin-rich foods.


Keratin is a group of proteins that form 10 nm intermediate filaments in all epithelial cells covering the inner and outer surfaces of the body, are insoluble in water and play an important role in hair, nail or skin care.
Keratin, the general name for a group of proteins naturally produced in the body, helps support the skin, heal wounds, and keep your nails and hair healthier and stronger.


There are 54 types of keratin in the body, 28 of which are type 1 and 26 are type 2.
Keratin, which is found in hair, nails and the epidermis, the outer layer of the skin, can also be found in glands and organs in the body.
Keratin (/ˈkɛrətɪn/) is one of a family of structural fibrous proteins also known as scleroproteins.


Alpha-keratin (α-keratin) is a type of keratin found in vertebrates.
Keratin is the key structural material making up scales, hair, nails, feathers, horns, claws, hooves, and the outer layer of skin among vertebrates.
Keratin also protects epithelial cells from damage or stress.


Keratin is extremely insoluble in water and organic solvents.
Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong unmineralized epidermal appendages found in reptiles, birds, amphibians, and mammals.


Excessive keratinization participate in fortification of certain tissues such as in horns of cattle and rhinos, and armadillos' osteoderm.
The only other biological matter known to approximate the toughness of keratinized tissue is chitin.
Keratin comes in two types, the primitive, softer forms found in all vertebrates and harder, derived forms found only among sauropsids (reptiles and birds).


Spider silk is classified as keratin, although production of the protein may have evolved independently of the process in vertebrates.
Keratin is the main component of skin and nails, as well as hair.
There is keratin protein in both the outer structure of the hair, called the cortex, and its inner structure.


Keratin is the main ingredient of hair strands.
Keratin in the hair is depleted due to external factors such as sun, pollution or chemicals, or changes in your lifestyle.
This loss results in dry, damaged and dull hair.


That's why it is necessary to get keratin support from outside.
Hair strands damaged by dye, blow dryer or straightener lose keratin and the hair acquires a bad and damaged appearance.



USES and APPLICATIONS of KERATIN:
Keratin uses the endoplasm of fish scales as raw material, and extracts the keratin essence in the fish scales by biotechnology.
Keratin has strong anti-stretching properties and acts as a cross-linking function in the protein peptide chain.
Keratin has high mechanical strength.


Keratin can be well absorbed by the skin.
The use of keratin keeps the skin elastic, soft and moisturised, prevents dry skin, reduces wrinkles and delays aging.
Keratin is suitable for skin care lotions, skin creams, firming creams, sunscreens and masks in cosmetics.


Keratin is the type of protein that makes up your hair, skin, and nails. Keratin can also be found in your internal organs and glands.
Keratin is a protective protein, less prone to scratching or tearing than other types of cells your body produces.
Keratin can be derived from the feathers, horns, and wool of different animals and used as an ingredient in hair cosmetics.


Since keratin is the structural building block of your hair, some people believe that keratin supplements, products, and treatments can help strengthen your hair and make it look healthier.
It is a hair care product we developed to help increase the flexibility of hair strands and make hair softer, smoother and more well-groomed, thanks to keratin and natural oils.


In addition to preserving the shape and volume of the hair by providing Keratin support to the hair, it aims to help the hair be easily combed and prevent frizz with the moisturizing support of Shea, Coconut, Argan and Avocado oils.
Keratin aims to support the care of hair loss and breakage with its Aloe Vera, Pine Turpentine and Sweet Almond oil content.


Keratin adds vitality to the hair, gives it strength and makes it look brighter.
Keratin, a powerful protein group, has a significant effect on hair when found naturally in the body.
Keratin, which is a beneficial protein when used as a supplement or taken through food, adds vitality to the hair, gives it strength and makes it look brighter.


Keratin, which is naturally present in the body and plays a role in improving hair, nail and skin health, is also often enriched with keratin in cosmetic treatments.
Keratin is also found naturally in some foods and can be taken as a supplement to meet the body's keratin needs.


Keratin prevents hair from frizzing and strengthens the hair shaft.
Keratin, a compound rich in both protein and sulfur, prevents hair from frizzing and supports healthy hair growth by strengthening the hair shaft.
Keratin prevents skin damage and helps keep skin fresh.


Keratin, in addition to its benefits for hair, is also an important protein for skin health.
Keratin, which naturally helps the skin stay fresher, prevents skin damage when used as a supplement and creates a healthier skin structure.
Keratin prevents nail breakage and makes nails look stronger.


Keratin, which is found in hair, the outer layer of the skin, glands and some organs, is also found in nails.
Nail breakage on headKeratin, which has the ability to make nails look stronger, especially against nail breakage, has a role in supporting nail
Keratin soothes and straightens wavy, curly and frizzy hair, including dyed hair.


Keratin is applied to the hair on the same day, making it washable and styleable.
Keratin does not require any extra chemicals or equipment during application.
With its effect lasting up to 4 months, hair becomes softer, brighter and healthier.


Keratin is applied to the hair to restore the hair strands to their former healthy appearance.
Thus, the hair looks brighter, softer and more well-groomed.


-Cosmetic Use:
*Creams for skins that aren't well-protected
*Treatments for nutrition and restructuring.
*Treatments for eyelashes with make-up.
*Shampoos and conditioners for hair that is prone to breakage.
*Hair items that are ideal for your hair.



APPLICATION OF KERATIN:
Keratin is for use by adults over 16 years of age and before application, test it on a small area of ​​your skin to avoid allergic reactions.
Take a sufficient amount from the bottle marked STEP 1 on damp hair and apply by massaging from the roots to the ends.
Rinse your hair with plenty of water and repeat the process.

Dry your hair and make sure it is not damp.
Shake the bottle labeled STEP 2 before use and divide your hair into 4 equal sections before application.
Apply Keratin to every section of hair you have separated, starting from 2 centimeters from the hair roots to the ends of the hair.

Comb your hair and make sure it is distributed evenly.
15 minutes for frizzy hair,
25 minutes for curly and wavy hair,

For very curly hair, leave it on for 40 minutes.
Dry your hair by combing it with the help of a blow dryer and a straightening brush so that it does not remain damp.
Straighten your hair from root to tip with the help of hair straightening tongs.

Rinse your hair with water for 5 minutes.
Take a small amount from the bottle labeled STEP 3, apply it to your hair and distribute it evenly with the help of a comb.
Leave it on for 10 minutes for thin hair, 15 minutes for normal hair, 20 minutes for thick hair for it to take effect.

Rinse with plenty of water for 8 minutes.
Dry your hair and style it as you wish.
Do not repeat the procedure for 10-14 days.
Do not apply for 10 days before or after hair dyeing.



BENEFITS AND RESULTS OF KERATIN:
People who use keratin on their hair report that their hair is smoother and easier to manage as a result.
The effects vary greatly depending on whether your hair is healthy to begin with, what the natural thickness of your hair is, and what kind of keratin treatment you use.
Keratin works by smoothing down the cells that overlap to form your hair strands.
The layers of cells, called the hair cuticle, theoretically absorb the keratin, resulting in hair that looks full and glossy.
Keratin also claims to make curly hair less frizzy, easier to style, and straighter in appearance.



THINGS YOU SHOULD PAY ATTENTION TO AFTER KERATIN CARE:
You should avoid washing your hair for a few days.
Since chlorinated or salty water will reduce the effect of keratin, you can take a break from activities such as pool or sea for a while.
You should prevent your scalp from sweating for 3 days immediately following the keratin treatment.
You should also make sure that the care products you use contain natural ingredients.
You can wait 1-2 weeks to continue your hair care routine and use hair masks.



DOES KERATIN TREATMENT STRAIGHTEN HAIR?
Keratin treatment does not completely straighten the hair.
Keratin treatment, which is often confused with a Brazilian blow dry, does not change your natural hair structure by preventing the hair from becoming more easily shaped and frizzy.
Brazilian blow dry is a process that is made with keratin but with a different technique and allows the hair to remain straight for up to 6 months.



HOW MANY DAYS SHOULD KERATIN CARE NOT BE WASHED?
After the keratin treatment, it is recommended not to wash your hair for a while so that the keratin loaded into your hair is accepted by all your hair strands.
Generally, this period is known as 2-3 days.
If your hair gets wet during this period, it is also recommended to dry Keratin and go over it with a straightener.



HAIT KERATIN:
Hair keratin is a protein that can be found in your skin, hair, and nails. Keratin is also present in the organs and glands of the body.
Keratin is a defensive protein that is less likely to be scratched or torn than other forms of cells produced by your body.



KERATIN POWDER
Keratin therapy users say that their hair is cleaner and easier to handle as a result of using it.
The results differ significantly based on whether your hair is safe, to begin with, how thick your hair is natural, and the keratin therapy you use.
Keratin functions by smoothing out the overlapping cells that make up your hair strands.
The hair cuticle, which is made up of layers of cells, absorbs the keratin, giving hair a full and shiny appearance.
Keratin is often said to make curly hair less frizzy, easy to style, and look straighter.



KERATIN TREATMENT
Keratin treatment is a hairstyling process that requires straightening and flattening of hair to offer it a smooth, straight, streamlined, and elegant look.
It has been used since the 1890s. During the 1950s, smoothing keratin was very common among black males and females of almost all races.



BIO KERATIN:
Peptides derived from hydrolyzed keratin with a high homology and bio-affinity for the keratin found in the hair, skin, and nails.
Heavy amount of hydrophobic amino acids, that improves moisture retention capability.



HOW TO USE KERATIN?
You can use Keratin whenever you need by spraying it on your hair from a distance of 15-20 cm.
Keratin is suitable for all hair types.
You can use Keratin before or after a shower.



WHAT IS KERATIN CARE?
In fact, the body naturally produces keratin for hair and nails.
The reason why your hair is shiny and your nails are vibrant depends on this keratin.
Keratin is loaded by professionals on hair that is damaged, has lost its vitality and has become dull due to various reasons.
This process, which makes the hair look more vibrant and healthy, is called keratin care.



WHAT DOES KERATIN CARE DO?
Thanks to keratin care, the hair looks more vibrant and shiny.
Problems such as frizz and frizz disappear for a few months.



KERATIN CARE BENEFITS
Of course, keratin treatment not only makes the hair shine, but also contains many benefits for the hair.
Moving on to what these benefits are;

*Smooth and shiny hair:
Keratin, which cares for the hair strands one by one, prevents the hair from becoming frizzy and frizzy, making it brighter.
Keratin also prevents the appearance of split hair ends.

*Long-term results:
If you take care of your hair care, Keratin will last up to 3-4 months.
During this period, your hair will be more vibrant and easier to shape.

*Healthy hair growth:
Thanks to keratin, which is a substance that the hair needs, the revitalized hair grows in a healthier way.
Strengthening the hair strands prevents breakage and ensures that the hair is well-groomed.



WHAT IS KERATIN CARE, HOW IS KERATIN HAIR CARE DONE?
-3 - Hair Care Beauty
How to do keratin care?
Keratin care, which is generally recommended to be done professionally, has recently become one of the treatments that most women do themselves at home.

Keratin care begins with washing your hair with a special shampoo.
This shampoo provides deep cleansing of the hair.
Keratin is then applied to the hair.

The hair is divided into several equal parts to penetrate each strand of hair.
Keratin is applied to the hair with a brush and spreads by combing to the ends of the hair.
After application, keratin is left on the hair for 20-30 minutes.

For fixation, the hair is dried with a blow dryer and the hair is blow dried.
*At this point, if you are doing it yourself at home, you should definitely use a hygienic mask.
The smoke and odor that emerges when keratin comes into contact with heat can burn your throat.

You should also be very careful when blow-drying your hair roots.
You can burn your scalp with a hot blow dryer to dry the keratin, which takes a while to dry.
This causes dandruff-like dead skin to appear over time.



FUNCTIONS OF KERATIN:
*effective safety from environmental threats
*Enhances and restores the micro-relief of the skin.
*Excellent hair conditioner and protectant.
*Strengthens the hair scales' cohesion.



WHAT IS KERATIN USED FOR?
Keratin helps form the epidermis, which is the outer layer of hair, nails and skin, strengthens the nail structure and increases its durability, and ensures that the hair has a shiny and healthy appearance.
Keratin also maintains the skin's elasticity and firmness.



THE BENEFITS OF KERATIN CAN BE LISTED AS FOLLOWS:
Keratin adds vitality to the hair, gives it strength and makes it look brighter.
Keratin prevents hair from frizzing and strengthens the hair shaft
Keratin prevents skin damage and helps keep skin fresh
Keratin prevents nail breakage and makes nails look stronger



WHAT IS KERATIN CARE?
Keratin care is a process applied to help straighten, smooth and revitalize hair, especially hair that is curly or damaged as a result of external factors.
Keratin is a protein produced naturally by the body, but it can also be obtained through supplements or foods.
In addition, keratin care is good for skin and nail health as well as hair.

What are the Keratin Types?
Keratin, which has 54 types in the body, is divided into two types. These are divided into type 1 and type 2.

Type 1:
28 of the 54 types of keratin in the human body are type I. 17 of these are skin cell (epithelial) keratins and 11 are hair keratins.
Most type I keratins (cytokeratins) consist of acidic and low-weight proteins.
Keratinv has many functions, including skin and hair health, including helping protect cells from internal forces in the body (mechanical stress).

Type 2:
The other 26 types of keratin in the human body are type II.
20 of these are skin cell keratins and 6 are hair keratins.
They consist of basic-neutral, high-weight proteins.
Their basic-neutral pH helps balance type I keratins and manage cell activity.



IN WHICH FOODS IS KERATIN FOUND?
Keratin, which is naturally found in the body, is also included in some foods, and it is possible to meet the body's keratin needs by consuming these foods.

Here are some foods containing keratin:
*Egg
*Carrot
*Mango
*Sweet potato
*Salmon



EXAMPLES OF OCCURRENCE OF KERATIN:
Alpha-keratins (α-keratins) are found in all vertebrates.
They form the hair (including wool), the outer layer of skin, horns, nails, claws and hooves of mammals, and the slime threads of hagfish.
The baleen plates of filter-feeding whales are also made of keratin.

Keratin filaments are abundant in keratinocytes in the hornified layer of the epidermis; these are proteins which have undergone keratinization.
They are also present in epithelial cells in general.
For example, mouse thymic epithelial cells react with antibodies for keratin 5, keratin 8, and keratin 14.

These antibodies are used as fluorescent markers to distinguish subsets of mouse thymic epithelial cells in genetic studies of the thymus.
The harder beta-keratins (β-keratins) are found only in the sauropsids, that is all living reptiles and birds.
They are found in the nails, scales, and claws of reptiles, in some reptile shells (testudines, such as tortoise, turtle, terrapin), and in the feathers, beaks, and claws of birds.

These keratins are formed primarily in beta sheets. However, beta sheets are also found in α-keratins.
Recent scholarship has shown that sauropsid β-keratins are fundamentally different from α-keratins at a genetic and structural level.
The new term corneous beta protein (CBP) has been proposed to avoid confusion with α-keratins.

Keratins (also described as cytokeratins) are polymers of type I and type II intermediate filaments that have been found only in chordates (vertebrates, amphioxus, urochordates).
Nematodes and many other non-chordate animals seem to have only type VI intermediate filaments, fibers that structure the nucleus.



GENES OF KERATIN:
The human genome encodes 54 functional keratin genes, located in two clusters on chromosomes 12 and 17.
This suggests that they originated from a series of gene duplications on these chromosomes.

The keratins include the following proteins of which KRT23, KRT24, KRT25, KRT26, KRT27, KRT28, KRT31, KRT32, KRT33A, KRT33B, KRT34, KRT35, KRT36, KRT37, KRT38, KRT39, KRT40, KRT71, KRT72, KRT73, KRT74, KRT75, KRT76, KRT77, KRT78, KRT79, KRT8, KRT80, KRT81, KRT82, KRT83, KRT84, KRT85 and KRT86 have been used to describe keratins past 20



WHAT SHOULD WE DO AFTER KERATIN CARE?
First of all, we should leave our hair keratinized for a few days and not wash it immediately.
In this way, keratin will penetrate into our hair thoroughly.
In the days after the care, Keratin is important for our scalp to breathe and not sweat.

That's why we should be careful not to let our scalp sweat.
As always, we should not use shampoos and hair care products that contain harmful chemicals.
After having a keratin treatment, we should avoid contact of our hair with salty or chlorinated water for a while.

For this reason, we can choose to do keratin care after the sea and pool season.
We should stop our classical daily or weekly hair care routines for a while.



ARE KERATIN TREATMENT AND BRAZILIAN BLOW DRY THE SAME THING?
One of the topics we often hear and wonder about is whether the two are the same thing.
While Brazilian blow dry is a method used by people who want to wear their hair straight for a while, keratin treatment is a treatment we use to make our hair look healthier and more well-groomed.

However, since the main ingredient used for Brazilian blow dry is mostly keratin, keratin care and Brazilian blow dry can be confused.
The distinction here is the application method of keratin treatment and Brazilian blow dry.
In this way, keratin care provides a deep care to the hair, while Brazilian blow dry creates a straightening effect for up to 6 months.



KERATIN CARE AT HOME?
If this is the question on your mind, the answer is right below.
Keratin care for your hair at home, step by step in this article.

Anti-hair loss shampoos , creams that provide easy combing, serums that nourish the roots, strengthening masks and much more...
All of these constitute the preferred products to obtain well-groomed hair and protect them sustainably.
If you want to take good care of your hair and ensure that they are healthy without going to the hairdresser, this article is for you.
By reading the rest of this article, where we talk about keratin care at home,you can learn what keratin is and how it benefits your hair.



WHAT ARE KERATINS BENEFITS FOR HAIR?
Keratin is actually an acid found naturally in humans and other vertebrates.
One of the functions of this acid is to provide energy support by reducing fat in muscle cells.
The benefits of keratin, which plays an important role in the structure of hair, skin, nails and other body tissues, for hair are listed below.

Elasticity:
Keratin provides elasticity to the hair strands.
In this way, the hair becomes more flexible, more resistant to external influences and can be shaped easily.

Strengthening:
Keratin strengthens hair strands and prevents breakage, wear and breakage.
Keratinprovides a stronger structure to the hair and supports the hair strands to be more durable.

Maintaining Moisture Balance:
Keratin helps hair strands maintain their natural moisture balance.
This ensures that the hair remains moisturized and protected from drying out.
Keratin can also reduce dry hair problems by helping the hair retain moisture better.

Resistance to Breakage:
Keratin protects the hair strands against external factors.
Keratin protects the hair exposed to factors such as sunlight, heat styling tools and chemical processes, preventing them from breaking and getting damaged.

Repair:
Keratin helps regenerate and repair hair strands.
Keratin repairs damage to hair, promotes healthy hair growth and can reduce hair loss.
After all this general information, we can move on to our main topic, keratin care at home.
If you are ready, we start.



KERATIN CARE STAGES:
Before you attempt this job , it is natural for you to have questions about how to do keratin care at home .
We aim to answer this question with this article.
By continuing reading, you can get an idea about doing keratin care at home .


*First Stage: Cleaning
Before starting keratin care, you need to clean your hair well.
Wash and rinse your hair with a suitable shampoo before keratin treatment.
Removing product residues and oil accumulated in your hair will increase the effect of keratin care.
It's up to us to say.


*Second stage: Dehumidification
Gently dry your hair with a towel; but do not use a hair dryer to dry it completely.
A slightly damp hair is more suitable for the keratin treatment.
Those who do keratin care at home know how important this process is.


*It's Time for Application
To perform keratin treatment with ingredients at home, choose one of the products you have purchased before.
At this stage, a keratin mask or keratin hair serum is generally preferred.
Apply the product to your hair according to the instructions and ensure that the keratin is thoroughly distributed throughout your hair.
Finally, leave the keratin product on your hair for the specified time.


*Optional: Straightening
Keratin treatment is usually completed with a straightening process.
You can use heat styling tools like a hair straightener or curling iron to straighten your hair.
To ensure full absorption of the keratin product, divide your hair into thin sections and smooth each section.
Be careful not to damage your hair by doing the process carefully.
If you do not intend to flatten it, you can skip this part.


*Wait
After completing your keratin treatment, you may need to let your hair rest for a certain period of time.
This time is necessary for the keratin product to penetrate the hair better.
A period of 24 to 72 hours is generally recommended for leaving the keratin product in the hair.
Just know that you should not wash your hair during this period.


*Rinsing and Styling
You can rinse your hair after the waiting time specified in the previous step is completed.
Style your hair after the first rinse.
After keratin treatment, your hair will be smoother and straighter.

What are you waiting for to style your hair with methods such as curling iron or blow dryer to give the desired shape?
Now that we have answered the question of how to do natural keratin care at home , it is time to take a look at the foods containing keratin.
Below you can find detailed information about which foods contain keratin .



WHICH FOODS CONTAIN KERATIN?
The important point here is to note that keratin is not found directly in foods because it is a protein naturally produced in the body.
However, it is very important to consume foods that contain the nutrients the body needs for healthy keratin production.
Here are the important nutritional sources for keratin production:

*Protein Sources:
Proteins, which are the main components of keratin; It is found in animal and plant sources such as meat, chicken, fish, eggs, dairy products and legumes.
These foods provide the basic building blocks for the body's keratin production.

*Biotin:
Biotin is an important nutrient for hair, skin and nail health.
It is found in foods such as eggs, avocados, almonds, walnuts, mushrooms, milk, yoghurt and fish.
Biotin deficiency can cause hair weakening and breakage.

*Zinc:
Zinc is important for maintaining healthy hair and hair follicles.
Eggs , red meat, seafood, pumpkin seeds, beans, almonds and nuts are sources of zinc.

*Iron:
Iron deficiency can cause hair loss.
Consuming iron-rich foods such as spinach, red meat, turkey, beans, lentils, tofu, grains and dried fruits is beneficial for hair health.

*Vitamin A:
Vitamin A is important for scalp health and sebum production.
It is found in foods such as carrots, sweet potatoes, spinach, kale, apricots, mangoes and salmon.

*Vitamin E:
Vitamin E preserves the moisture of the hair and is beneficial for scalp health.
It is found in foods such as almonds, hazelnuts, peanuts, sunflower oil, olive oil and avocado.

Including various protein sources and other nutrients necessary for keratin production in the diet can support hair health.
However, for healthy hair, Keratin is extremely important to pay attention not only to nutrition but also to general lifestyle.
A healthy lifestyle includes factors such as regular sleep, adequate water consumption and stress management.



HOW OFTEN SHOULD KERATIN TREATMENT BE DONE?
So, how often should keratin care be done ?
Here is the answer!

*Keratin care frequency;
Keratin may vary depending on hair type, hair condition and properties of the product used.
The effect of keratin treatment usually decreases over time and the hair returns to its previous state.
Therefore, it is important to repeat keratin care regularly.
Here are the recommended frequencies for keratin care:

*Professional Keratin Care:
Professional keratin care is generally recommended for a period of 2 to 4 months.
This time may vary depending on the hair growth rate, the quality of the keratin product and personal preferences.
Some people may experience effective results for longer periods of time, while others may prefer to repeat it more frequently.

*Keratin Care at Home:
The effect of keratin care products used at home may last shorter than professional applications.
It is important to act in accordance with the instructions for use of home keratin care products.
Keratin treatment at home can be repeated every 2 to 3 weeks.


The important thing here is to observe the condition of your hair and act according to your hair's needs to decide how often you should do keratin care.
Experts recommend that you should care for your hair regularly to keep it healthier and smoother.
Additionally, using shampoo, conditioner and other hair care products suitable for your hair type will also support your hair health.



KERATIN CARE BENEFITS
Now we come to the benefits of keratin care .
You can see what keratin contributes to your hair in the following items.

Keratin provides strength and durability to hair strands.
Keratin supports the hair to be more resistant to breakage, wear and breakage.

Keratin treatment ensures that the hair stays straight for longer when straightened.
Wavy or frizzy hair is reduced, providing a smoother appearance for a longer time after straightening.

Keratin care increases the shine of hair.
Hair looks healthier and more vibrant.

Keratin protects the hair strands against external factors.
Keratin protects the hair exposed to factors such as sunlight, heat styling tools and chemical processes, preventing them from breaking and getting damaged.

Keratin helps hair strands maintain their natural moisture balance.
Keratin preserves the moisture of the hair, prevents it from drying out and ensures better moisture retention.
If you have obtained detailed information about whether keratin care can be done at home , it is time to enlighten yourself about summer hair care.



PROTEIN STRUCTURE OF KERATIN:
The first sequences of keratins were determined by Israel Hanukoglu and Elaine Fuchs (1982, 1983).
These sequences revealed that there are two distinct but homologous keratin families, which were named type I and type II keratins.

By analysis of the primary structures of these keratins and other intermediate filament proteins, Hanukoglu and Fuchs suggested a model in which keratins and intermediate filament proteins contain a central ~310 residue domain with four segments in α-helical conformation that are separated by three short linker segments predicted to be in beta-turn conformation.
This model has been confirmed by the determination of the crystal structure of a helical domain of keratins.

*Type 1 and 2 Keratins:
The human genome has 54 functional annotated Keratin genes, 28 are in the Keratin type 1 family, and 26 are in the Keratin type 2 family.
Fibrous keratin molecules supercoil to form a very stable, left-handed superhelical motif to multimerise, forming filaments consisting of multiple copies of the keratin monomer.

The major force that keeps the coiled-coil structure is hydrophobic interactions between apolar residues along the keratins helical segments.
Limited interior space is the reason why the triple helix of the (unrelated) structural protein collagen, found in skin, cartilage and bone, likewise has a high percentage of glycine.

The connective tissue protein elastin also has a high percentage of both glycine and alanine.
Silk fibroin, considered a β-keratin, can have these two as 75–80% of the total, with 10–15% serine, with the rest having bulky side groups.

The chains are antiparallel, with an alternating C → N orientation.
A preponderance of amino acids with small, nonreactive side groups is characteristic of structural proteins, for which H-bonded close packing is more important than chemical specificity.


*Disulfide bridges:
In addition to intra- and intermolecular hydrogen bonds, the distinguishing feature of keratins is the presence of large amounts of the sulfur-containing amino acid cysteine, required for the disulfide bridges that confer additional strength and rigidity by permanent, thermally stable crosslinking—in much the same way that non-protein sulfur bridges stabilize vulcanized rubber.

Human hair is approximately 14% cysteine.
The pungent smells of burning hair and skin are due to the volatile sulfur compounds formed.
Extensive disulfide bonding contributes to the insolubility of keratins, except in a small number of solvents such as dissociating or reducing agents.

The more flexible and elastic keratins of hair have fewer interchain disulfide bridges than the keratins in mammalian fingernails, hooves and claws (homologous structures), which are harder and more like their analogs in other vertebrate classes.

Hair and other α-keratins consist of α-helically coiled single protein strands (with regular intra-chain H-bonding), which are then further twisted into superhelical ropes that may be further coiled.
The β-keratins of reptiles and birds have β-pleated sheets twisted together, then stabilized and hardened by disulfide bridges.

Thiolated polymers (=thiomers) can form disulfide bridges with cysteine substructures of keratins getting covalently attached to these proteins.
Thiomers exhibit therefore high binding properties to keratins found in hair, on skin and on the surface of many cell types.


*Filament formation:
It has been proposed that keratins can be divided into 'hard' and 'soft' forms, or 'cytokeratins' and 'other keratins'.
That model is now understood to be correct.
A new nuclear addition in 2006 to describe keratins takes this into account.


*Keratin filaments are intermediate filaments.
Like all intermediate filaments, keratin proteins form filamentous polymers in a series of assembly steps beginning with dimerization; dimers assemble into tetramers and octamers and eventually, if the current hypothesis holds, into unit-length-filaments (ULF) capable of annealing end-to-end into long filaments.



WHAT IS IT HAIR CARE AND WHAT DOES KERATIN CARE DO?
When it comes to hair care, one of the treatments that comes to our mind is keratin care.
Topic today is keratin hair care, which we apply to our hair in hairdressers or at home.



SO WHAT IS THIS KERATIN HAIR CARE?
It produces keratin naturally for the body, hair and nails.
In this way, our nails become strong and vibrant, and our hair becomes healthy and shiny.
When this naturally produced keratin is not enough for our hair for various reasons, we can apply keratin care as an external supplement.
In this way, our hair looks more vibrant, well-groomed and healthy.



WHAT ARE THE BENEFITS OF KERATIN CARE FOR HAIR?
As we mentioned, keratin treatment is a process that will make our hair look brighter and healthier.
With correct application, Keratin repairs hair damage and protects the hair. With keratin care, our hair gains a shiny structure and a shine and vitality that lasts for 3-4 months. It also makes the hair more voluminous.



HOW IS KERATIN CARE DONE?
Keratin care can be done professionally at the hairdresser, or it can be done at home with care kits.
Depending on your preference and needs, you can have keratin treatment at a hairdresser at regular intervals or you can do it at home.



KERATIN CARE AT THE HAIRDERSSER:
It starts with thoroughly cleaning and purifying your hair by washing it with a shampoo suitable for your hair structure.
Then, the hair is divided into pieces and keratin is applied to each piece with a brush, touching every strand.
Afterwards, the keratin is left on the hair for a while and the hair is straightened with a straightener or the keratin is allowed to penetrate into the hair with the help of a blow dryer to ensure that it is thoroughly processed and fixed.



KERATIN CARE AT HOME:
The difference between keratin treatment done at a hairdresser is generally related to the products we use.
While professional products are used in hairdressers, we can use a keratin care product with quality ingredients to perform keratin care at home.

Hair is cleaned and purified.
Afterwards, the hair is divided into pieces and keratin is applied.
After waiting for a while, the keratin is ensured to penetrate thoroughly into the hair with the help of a straightener or blow dryer.

One of the things we need to pay attention to in this regard is that we should be careful to use a mask when doing keratin care at home and when applying a straightener or blow dryer to our keratin hair.
If possible, let's open the ventilation or windows.
Because the smoke that comes out when we heat keratin hair can disturb us.



WHAT ARE THE BENEFITS OF KERATIN CARE?
Hair is exposed to many damaging factors such as seasonal changes, heat treatments, dyeing and lightening processes, styling sprays and creams we use, and therefore it becomes weak and worn out.
Moreover, irregular diet or unhealthy diet causes the hair to weaken and the keratin in the hair to disappear.

If your hair has become weak, damaged and faded due to these factors, keratin care comes to your rescue.
Keratin care provides protection against external factors by surrounding the hair strands like a protection shield.
The stronger hair strand is less affected by external factors.

With care products containing keratin, the keratin that the hair needs and lost is recharged.
In particular, split ends are repaired and the hair becomes more vibrant, brighter, softer and smoother.
Most importantly, hair grows healthier and stronger.
Thus, there is an increase in hair growth rate.



WHICH HAIR NEEDS KERATIN?
If your hair strands have become thinner or you notice that they are getting thinner, if your hair is more dull and lost its color, if you are losing a lot of hair and even break off in clumps, and if it is hard, difficult to comb, and even more difficult to style, it means that your hair needs this care.



HOW TO MAKE A KERATIN MASK?
Doing this care, which will repair your damaged hair and return Keratin to its former strong and vibrant state, is not as difficult as it seems.
You can also do Keratin is left on the hair for 15-20 minutes, and the hair is supported to absorb the product with a blow dryer, provided that the recommended temperatures are not too high.

Then, the hair is washed and dried, and a layer of hair is blow-dried with a machine such as a blow dryer or straightener.
When the treatment is completed, the keratin in your hair increases and the change is visible and your hair gets a great shine.
Applying this care to your hair periodically will be beneficial for the continuity of the proteins in your hair structure.



HOW TO PERFORM KERATIN CARE?
Generally, when keratin care is mentioned, everyone thinks of hair straightening procedures performed at the hairdresser.
However, keratin is a very important substance for hair, and keratin-containing care products should be used regularly in order for the hair to grow healthy and without breakage.
You should apply the herbal keratin shampoo by massaging it into your scalp, and apply the hair care cream by concentrating on the ends of your hair.



PRODUCTION OF KERATIN:
production of small proline-rich (SPRR) proteins and transglutaminase which eventually form a cornified cell envelope beneath the plasma membrane

*terminal differentiation:
loss of nuclei and organelles, in the final stages of cornification
Metabolism ceases, and the cells are almost completely filled by keratin.

During the process of epithelial differentiation, cells become cornified as keratin protein is incorporated into longer keratin intermediate filaments.
Eventually the nucleus and cytoplasmic organelles disappear, metabolism ceases and cells undergo a programmed death as they become fully keratinized.
In many other cell types, such as cells of the dermis, keratin filaments and other intermediate filaments function as part of the cytoskeleton to mechanically stabilize the cell against physical stress.

Keratin does this through connections to desmosomes, cell–cell junctional plaques, and hemidesmosomes, cell-basement membrane adhesive structures.
Cells in the epidermis contain a structural matrix of keratin, which makes this outermost layer of the skin almost waterproof, and along with collagen and elastin gives skin its strength.

Rubbing and pressure cause thickening of the outer, cornified layer of the epidermis and form protective calluses, which are useful for athletes and on the fingertips of musicians who play stringed instruments.
Keratinized epidermal cells are constantly shed and replaced.

These hard, integumentary structures are formed by intercellular cementing of fibers formed from the dead, cornified cells generated by specialized beds deep within the skin.
Hair grows continuously and feathers molt and regenerate.

The constituent proteins may be phylogenetically homologous but differ somewhat in chemical structure and supermolecular organization.
The evolutionary relationships are complex and only partially known.
Multiple genes have been identified for the β-keratins in feathers, and this is probably characteristic of all keratins.


*Silk:
The silk fibroins produced by insects and spiders are often classified as keratins, though it is unclear whether they are phylogenetically related to vertebrate keratins.
Silk found in insect pupae, and in spider webs and egg casings, also has twisted β-pleated sheets incorporated into fibers wound into larger supermolecular aggregates.

The structure of the spinnerets on spiders’ tails, and the contributions of their interior glands, provide remarkable control of fast extrusion.
Spider silk is typically about 1 to 2 micrometers (µm) thick, compared with about 60 µm for human hair, and more for some mammals.
The biologically and commercially useful properties of silk fibers depend on the organization of multiple adjacent protein chains into hard, crystalline regions of varying size, alternating with flexible, amorphous regions where the chains are randomly coiled.

A somewhat analogous situation occurs with synthetic polymers such as nylon, developed as a silk substitute.
Silk from the hornet cocoon contains doublets about 10 µm across, with cores and coating, and may be arranged in up to 10 layers, also in plaques of variable shape.
Adult hornets also use silk as a glue, as do spiders.


Glue:
Glues made from partially-hydrolysed keratin include hoof glue and horn glue.


*Clinical significance
Abnormal growth of keratin can occur in a variety of conditions including keratosis, hyperkeratosis and keratoderma.
Keratin is highly resistant to digestive acids if ingested.
Cats regularly ingest hair as part of their grooming behavior, leading to the gradual formation of hairballs that may be expelled orally or excreted.
In humans, trichophagia may lead to Rapunzel syndrome, an extremely rare but potentially fatal intestinal condition.


*Diagnostic use
Keratin expression is helpful in determining epithelial origin in anaplastic cancers.
Tumors that express keratin include carcinomas, thymomas, sarcomas and trophoblastic neoplasms.

Furthermore, the precise expression-pattern of keratin subtypes allows prediction of the origin of the primary tumor when assessing metastases.
For example, hepatocellular carcinomas typically express CK8 and CK18, and cholangiocarcinomas express CK7, CK8 and CK18, while metastases of colorectal carcinomas express CK20, but not CK7



PHYSICAL and CHEMICAL PROPERTIES of KERATIN:
Appearance: light yellow powder
Moisture: ≤6.0%
PH value: 4.5 ~ 6.5 (5% aqueous solution)
Mercury: ≤0.5mg/kg
Arsenic: ≤0.5mg/kg
Lead: ≤1.0mg/kg
Total bacteria: ≤1000cfu/g
Coliform: ≤30MPN/100g
Pathogenic bacteria: not detected
Protein content: ≥90.0%



FIRST AID MEASURES of KERATIN:
-Description of first-aid measures:
*If inhaled:
If breathed in, move person into fresh air.
*In case of skin contact:
Wash off with soap and plenty of water.
*In case of eye contact:
Flush eyes with water as a precaution.
*If swallowed:
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of KERATIN:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Keep in suitable, closed containers for disposal.



FIRE FIGHTING MEASURES of KERATIN:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
No data available



EXPOSURE CONTROLS/PERSONAL PROTECTION of KERATIN:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
*Skin protection:
Handle with gloves.
Wash and dry hands.
*Body Protection:
Impervious clothing
*Respiratory protection:
Respiratory protection not required.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of KERATIN:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Store in cool place.
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.



STABILITY and REACTIVITY of KERATIN:
-Reactivity:
No data available
-Chemical stability:
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available
-Conditions to avoid:
No data available

Kératine hydrolysée
Coco fatty acid ;coconut acid; fatty acids, coco; coconut fatty acid cas no: 61788-47-4
KOKO YAĞI ASIDI
SYNONYM Fats and Glyceridic oils, fish; Fish Oil is the oil obtained from the head, tail and stomach of various species of fish CAS #8016-13-5
KOLLIPHOR TPGS
Kolliphor TPGS Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS): Solution for insolubility Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) – D-alpha tocopheryl polyethylene glycol 1000 succinate (TPGS) – is a water-soluble derivative of vitamin E that can directly enhance the bioavailability of poorly soluble actives. TPGS is commonly used in pharmaceutical and nutraceutical formulations. Key Features of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) Based on natural-source vitamin E from BASF Conforms to USP-NF monograph “Vitamin E Polyethylene Glycol Succinate” Produced according to IPEC-PQG GMP guidelines No chlorinated solvents used Detailed technical and regulatory information available Enhanced delivery of life-saving drugs Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) directly increases the bioavailability and delivery of poorly soluble drugs. TPGS can be used in oral, topical and parenteral dosage forms. It is also used in dietary supplements, cosmetic applications and food. Key benefits for customers Cognis is a leading supplier of natural-source vitamin E and pharma-grade excipients, and has considerable expertise in solubilizers. Using its own vitamin E feedstocks, BASF guarantees consistent quality and a competitive, reliable supply of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS). In accordance with stringent industry requirements, BASF maintains the highest manufacturing standards, with full supporting documentation. TPGS from BASF offer high solubilisation effectiveness. BASF offers a global sales network plus technical and regulatory support. Applications of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS): -Drug solubilizer -Absorption enhancer -Emulsifier -Vehicle for lipid-based drug delivery -Source of natural vitamin E -Antioxidant BASF will transfer the pharmaceutical production of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) (Speziol TPGS Pharma, vitamin E polyethylene glycol succinate), manufactured at the company’s Kankakee, Illinois (USA), site, to its Minden, Germany, facility. The transition is expected to be completed by the first quarter of 2014. “Expanding the Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) manufacturing capacity at our Minden site is another example of BASF’s commitment to the pharmaceutical and dietary supplement market. The relocation creates a more centralized production facility, reduces complexity in the production setup, and provides room for future expansion,” said Dr. Thorsten Schmeller, Head of Global Marketing New Products at BASF’s Global Business Unit Pharma Ingredients & Services. The Minden site has manufactured active pharmaceutical ingredients (APIs) and excipients under cGMP for more than 70 years and is regularly inspected by the FDA and European health authorities. Schmeller: “Thanks to the ICH Q7 quality management standards at our Minden site, we will be able to offer a Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) grade that fulfills the requirements of an API.” Commitment to a seamless transition Until the production in Minden is fully operational, BASF will continue to manufacture Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) at the Kankakee site, which will fully support pharmaceutical and nutraceutical customers during the transition. “We have scheduled a generous supply overlap that we expect allows for a seamless transition,” added Schmeller. “Our projection also takes into account the appropriate qualification period required to transition products used in pharmaceutical applications.” Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) production at the Minden site is expected to start in the first quarter of 2013. The Kankakee site remains an important production facility for BASF’s nutrition and health business. Besides food ingredients, the company manufactures ingredients for soaps, shampoos, detergents, coatings, inks and adhesives at the site. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) is a water-soluble derivative of vitamin E that can directly enhance the bioavailability of poorly soluble active substances. It is commonly used in pharmaceutical and nutritional formulations, but also in cosmetics. Additionally it has plasticizing effects that are very beneficial for emerging platform technologies in the pharmaceutical industry such as hot melt extrusion (HME). Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) is a water-soluble derivative of vitamin E that can directly improve the bioavailability of poorly soluble active substances. BASF Global Business Unit Pharma Ingredients & Services Global Marketing New Products head Thorsten Schmeller said the relocation creates a centralized production facility, reducing complexity in the production setup, while providing room for future expansion. The company said until the production in Minden is fully operational, it will continue to manufacture Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) at the Kankakee site. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) is commonly used in pharmaceutical and nutritional, as well as in cosmetic formulations. The production of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) at the Minden site is likely to begin in the first quarter of 2013 with the completion scheduled to Q1, 2014. D-ɑ-tocopheryl polyethylene glycol succinate (Vitamin E Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) or Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)) has been approved by FDA as a safe adjuvant and widely used in drug delivery systems. The biological and physicochemical properties of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) provide multiple advantages for its applications in drug delivery like high biocompatibility, enhancement of drug solubility, improvement of drug permeation and selective antitumor activity. Notably, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can inhibit the activity of ATP dependent P-glycoprotein and act as a potent excipient for overcoming multi-drug resistance (MDR) in tumor. In this review, we aim to discuss the recent advances of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) in drug delivery including Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) based prodrugs, nitric oxide donor and polymers, and unmodified Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) based formulations. These potential applications are focused on enhancing delivery efficiency as well as the therapeutic effect of agents, especially on overcoming MDR of tumors. It also demonstrates that the clinical translation of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) based nanomedicines is still faced with many challenges, which requires more detailed study on Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) properties and based delivery system in the future. Vitamin E has been identified as an essential factor for reproduction since 1922 1. With further investigation, it has been found with other functions involving antioxidant, anti-thrombolytic and other therapeutic effects 2, 3. However, the poor water solubility of vitamin E has greatly limited its application 4. Vitamin E d-ɑ-tocopheryl poly(ethylene glycol) 1000 succinate (simply as Vitamin E Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) or Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)), synthesized by esterification of vitamin E succinate with poly(ethylene glycol) (PEG) 1000, is a water-soluble derivative of natural vitamin E 5. It has an amphiphilic structure comprising hydrophilic polar head portion and lipophilic alkyl tail. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can be functionalized as an excellent solubilizer, emulsifier, permeation and bioavailability enhancer of hydrophobic drugs 6. Meanwhile, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can act as an anticancer agent, which has been demonstrated to induce apoptogenic activity against many cancer types. It can target the mitochondria of cancer cells, resulting in the mitochondrial destabilisation for activation of mitochondrial mediators of apoptosis 7. Interestingly, it has been documented that Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can selectively induce apoptosis in tumor cells while exhibited nontoxicity to normal cells and tissues 8. Multi-drug resistance (MDR) remains as a significant impediment to successful chemotherapy in clinical cancer treatment. What's worse, decades of research has identified that this phenomenon exists in nearly every effective drug, even the newest therapeutic agents 9. Therefore, how to effectively reverse drug resistance plays a critical role in achieving satisfied therapeutic effect in cancer treatment. It has been demonstrated that various mechanisms are involved in MDR including decreased drug influx, increased drug efflux, changed drug metabolism and promoted anti-apoptotic mechanism 10. Among them, the drug efflux mediated by ATP-binding cassette transporter P-glycoprotein (ABCB1) is one of the most investigated and characterized mechanisms for MDR. P-glycoprotein (P-gp) has 12 transmembrane regions to bind hydrophobic substrate drugs and two ATP-binding sites to transport drug molecules 11. It can pump out P-gp substrate drugs to the extracellular space and thus decrease the intracellular drug accumulation. Over the past few decades, considerable efforts have been devoted to exploring P-gp inhibitors for overcoming MDR. Several nonionic surfactants such as Pluronic, Tweens, Span and Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) have been found with the ability to inhibit P-gp activity 12, 13. Though the exact mechanism of P-gp inhibition by these surfactants remains unclear, steric blocking of substrate binding 14, alteration of membrane fluidity 15 and inhibition of efflux pump ATPase 16, 17 have been proposed as the potential mechanisms. As a widely used adjuvant in drug delivery, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) has been shown as the most potent and commercially available P-gp inhibitor among these surfactants 18. As a membrane transporter of ATP-binding cassette family, P-gp can pump out the substrate drug via an ATP-dependent mechanism 19. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can target the mitochondria and cause its dysfunction, resulting in the depletion of intracellular ATP. The reduced ATP level can then influence the activity of P-gp and decrease the drug efflux to extracellular space 20. Besides, the hydrolysis of ATP by ATPase is critical for converting the P-gp transporter to an active conformational state for substrate drug efflux 16. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) itself cannot stimulate ATPase activity as it is not a substrate of P-gp, but can inhibit the substrate induced ATPase activity 21. In our previous works, we have demonstrated that Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can significantly enhance the intracellular accumulation and cytotoxicity of chemotherapeutics to drug resistant breast adenocarcinoma cells (MCF-7/ADR) and human ovarian cancer cells (A2780/T) 22-24. Since Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) has been approved by the FDA as a safe pharmaceutical adjuvant, it has been extensively used in drug delivery systems as surfactant, solubilizer, stabilizer and P-gp inhibitor for enhancing bioavailability and reversing MDR. In our previous reviews 5, 6, we discussed Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) as a molecular biomaterial and its original application in drug delivery. In this review, we focused on the progress of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) in drug delivery in recent five years, which took advantages of the P-gp inhibiting ability and other basic properties. We summarized the applications of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) based prodrugs, nitric oxide (NO) donor and polymers for overcoming MDR and delivering therapeutic agents. We also discussed the unmodified Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) based formulations applied in reversing MDR, improving oral availability and enhancing drug permeation. We expect this review will give new inspiration for the application of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) in overcoming MDR and drug delivery. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) as a surfactant Poor water solubility and/or poor permeability remain as the major obstacles for therapeutic drugs to exert maximum activity. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can be applied as solubilizer, absorption and permeation enhancer, emulsifier as well as surface stabilizer in drug delivery. It has been widely used in fabricating nanodrugs or other formulations for many poorly water-soluble or permeable drugs, especially for biopharmaceutics classification system (BCS) class Ⅱ and Ⅳ drugs 5, 6. In addition, it has been reported that Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) exhibited strong enhancement on the secretion of chylomicrons at low concentration and enhanced the intestinal lymphatic transport 25, which would further improve drug absorption ability. As a surfactant, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) shows outstanding capability to increase drug absorption through different biological barriers. For example, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) was used to fabricate repaglinide nanocrystals for enhancing saturation solubility and oral bioavailability up to 25.7-fold and 15.0-fold compared with free drug, respectively 26. In Ussing chambers transport studies, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can enhance drug permeation in colonic tissue 27. In addition, the influence of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) on the intestinal absorption ability of icariside Ⅱ was investigated in Caco-2 monolayer model and a four-site rat intestinal perfusion model. In Caco-2 monolayer model, the apparent permeability coefficients value of icariside Ⅱ was increased and the efflux ratio was remarkably reduced owing to the effect of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS). The four-site rat intestinal perfusion model investigation further showed significantly increased permeability of icariside Ⅱ in ileum and colon 28. Similar results were found in Caco-2 monolayer model with rhodamine123 (Rh123) in the presence of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) 29. Interestingly, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can also act as a pore-forming agent in the fabrication of nanoparticles with high drug encapsulation efficiency, small particle size and fast drug release 30. Besides, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can be used as emulsifier or surface stabilizer for the preparation of drug formulations as the hydrophobic portion can entrap hydrophobic drug and the hydrophilic part can stabilize the formulations. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) as a P-gp inhibitor for overcoming MDR Drug resistance of cancer cells can restrict the therapeutic efficacy in chemotherapeutic treatment. As the ATP dependent membrane transporter, P-gp has been one of primary causes for MDR. It can pump out the P-gp substrate drugs to decrease intracellular drug accumulation, thus reducing the cytotoxic effect of chemotherapeutic drugs in drug resistant cancer treatment. Over the past decades, there have been continuous interests to combine P-gp substrate drugs with inhibitor or some polymer with P-gp inhibiting capability in formulations for overcoming MDR 31. Rh123, a P-gp substrate, is usually used as the model drug to study the intracellular retention of drug in MDR tumor cells. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can significantly increase the intracellular accumulation of Rh123 in drug-resistant tumor cells compared with free Rh123, which was evidenced from the flow cytometry and confocal microscope analysis 32. It seems that Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can effectively inhibit the activity of P-gp to overcome MDR. Since the efflux transporter P-gp is ATP-dependent, the depletion of ATP plays a very important role in overcoming MDR. The MDR reversing effect of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) is mainly attributed to its dual actions, the inhibition of mitochondrial respiratory complex Ⅱ for shorting ATP supply and the suppression of substrate induced P-gp ATPase activity for blocking ATP utilization 20, 21, 33, 34. Mitochondrial respiratory complex Ⅱ, also called succinate dehydrogenase, plays an important role in mitochondrial electron transport, which is an essential part in the tricarboxylic acid cycle as well as the mitochondrial respiratory chain 35. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can bind with mitochondrial respiratory complex Ⅱ and induce subsequent mitochondrial dysfunction, resulting in significant depletion of intracellular energy 20, 36. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can accumulate in mitochondria and inhibit the activity of complex Ⅱ, and consequently disrupt the electron transfer and activate calcium channel, which would result in the overload of calcium and ensuing dysfunction of mitochondria. Mitochondrial dysfunction is characterized by the dissipating effect on mitochondrial membrane potential, decreased ATP level and increased reactive oxygen species (ROS) generation 37. Furthermore, the mitochondrial targeting ability of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) may accelerate the mitochondrial dysfunction 32, 38. Substrate induced P-gp ATPase activity suppression is another mechanism for Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) to decrease drug efflux 21. ATPase activity can be stimulated by the binding of substrate to transmembrane regions of P-gp 39. Subsequently, ATP is transformed into adenosine diphosphate (ADP) for the energy supply of drug efflux. Unlike the classical P-gp inhibitor verapamil, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) is not a substrate of P-gp and shows no competitive inhibition effect of substrate binding. The steric blocking function of the binding site and/or allosteric modulation of P-gp appear to be the ATPase inhibition mechanism. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) as a selective anticancer agent for synergistic antitumor effects Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can induce apoptosis and exhibits selective cytotoxic effects against cancer cells, which can be combined with chemotherapeutic drugs for reducing side effect and increasing treatment efficiency. There is significant different response on normal immortalized breast cells and cancer cells after Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) treatment. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can trigger the apoptotic signaling pathways and induce G1/S cell cycle arrest in breast cancer cells MCF-7 and MDA-MB-231, but no remarkable effect on non-tumorigenic cells MCF-10A and MCF-12F 40. Coincidentally, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can induce apoptosis on T cell acute lymphocytic leukemia Jurkat clone E6-1 cells, but not on human peripheral blood lymphocytes. The apoptosis was evidenced by increased nuclear DNA fragmentation, enhanced cell cycle arrest and reduced mitochondrial membrane potential 41. The selective apoptosis mechanisms of cancer cells mediated by Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) are complicated and can be listed as follows: ROS inducer Similar to α-tocopheryl succinate (α-TOS), Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can induce cancer cell apoptosis through the destruction and inhibition of mitochondrial respiratory complex Ⅱ 33, 41. The subsequent electron transfer chain disruption can promote ROS generation 20. The escalated intracellular ROS, a mediator of apoptosis, can induce DNA damage and the oxidation of lipid, protein and enzyme, leading to cell destruction 42. Besides, it has been demonstrated that ROS-mediated apoptosis mechanism was correlated with the selective anticancer activity as tumor cells could be more sensitive to ROS than normal cells 43-45. Compared with TOS, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) exhibited enhanced ROS generation capability 46. Downregulation of anti-apoptotic proteins Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can inhibit the phosphorylation of protein kinase B (PKB or AKT) and then downregulate the anti-apoptotic proteins Survivin and Bcl-2, which can induce the activation of caspase-3 and -7 for caspase-dependent programmed cell death 40. Concurrently, caspase-independent programmed cell death and G1/S phase cell cycle arrest also occurred 40, 41. Survivin and Bcl-2 are usually overexpressed in most cancer cells while remarkably reduced in normal cells 47. This may be the main reason for the selective cytotoxicity of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS). DNA damage Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can induce both caspase-dependent and caspase-independent DNA damage. This kind of DNA damage was observed in androgen receptor positive (AR+) LNCaP cells but not in AR- DU145 and PC3 cells, which was related to the cellular microenvironment 48. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX conjugate Doxorubicin (DOX) is a P-gp substrate and broad spectrum anticancer drug. However, the acquired drug resistance of DOX is an obstacle to its clinical applications in the progress of cancer therapy. Bao et al. 23 developed a pH-sensitive Schiff base-linked prodrug, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-CH=N-DOX (also called TD), by conjugating DOX with Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) for overcoming MDR. This prodrug can self-assemble into stable micelles in physiological condition and realize in vivo tumor targeting and long blood circulation by introducing a PEGylated lipid. It was the first time to provide a “molecular economical” way to combat tumor as the system combined the tumor targeting from the integrin receptor ligand peptide cyclic RGD (cRGD), long circulation property from PEGylated lipid, overcoming MDR from the material Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) and stimuli-responsive release from Schiff based linker. The formulated hybrid micelles showed pH-sensitive drug release profile and obvious particles size change in pH 5.0 buffer which simulated the endo/lysosomal acidic environment. It also demonstrated increased DOX uptake by flow cytometry and confocal microscope analysis, and enhanced retention through in vivo pharmacokinetics compared with free drug. DOX exhibited good retention in drug sensitive MCF-7 cells during incubation. On the contrary, free drug showed much low DOX content and remarkably reduced retention in MCF-7/ADR cells even with extended incubation time. Both the P-gp inhibitors of verapamil and Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) can increase the drug accumulation in MCF-7/ADR cells. The prodrug micelles achieved the similar drug uptake and retention trend with the admixture of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) and DOX in MCF-7/ADR cells. It seems that the rapidly dissociated Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) from the internalized micelles can inhibit the P-gp activity and retain DOX for subsequent cytotoxicity against MDR tumors. The enhanced cytotoxicity and apoptosis was induced by the hybrid micelles in MCF-7/ADR cells compared with free DOX as the half-maximal inhibitory concentrations (IC50) of hybrid micelles was 95-fold lower than that of free drug after 72 h incubation. The mechanism of antitumor efficacy was further investigated through the analysis of intracellular ROS production, change of mitochondrial membrane potential (ΔΨm) and intracellular ATP level (Figure ​Figure22B). The accumulation of ROS, decreased mitochondrial membrane potential and decreased ATP generation from the hybrid micelles may contribute to the P-gp inhibition by Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) with cutting off the energy supply from the 'cellular power plants' of mitochondria. The prodrug exhibited significant growth inhibition on MCF-7/ADR tumor (Figure ​Figure22C) and also tumor growth/metastasis inhibition on murine melanoma B16F10 and hepatocarcinoma H22 with cRGD decorated on the hybrid micelles. It provided a safe and simple prodrug platform to relieve the burden from delivery system and improve the therapeutic efficiency of nanomedicine through the rational design of prodrug for effective cancer treatment. Some other Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX prodrugs were also designed and constructed 55-57. Feng's group 55 developed Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX prodrug by directly conjugating succinic anhydride modified Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) with DOX. The prodrug showed improved cell uptake and cytotoxicity. Compared with free drug, 4.5- and 24-fold of half-life (t1/2) and area under curve (AUC) were found in Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX prodrug, respectively. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX-folic acid conjugate (Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX-FOL) was further introduced for targeted chemotherapy with higher therapeutic effects and fewer side effects 56. Moreover, the prodrug of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX can also be applied to package drug for combinational therapy. Hou et al. 57 constructed an acid-sensitive Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX prodrug by firstly synthesizing a pH-sensitive cis-aconitic anhydride-modified DOX and then conjugating with Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS). The prodrug can self-assemble into nanoparticles. Photosensitizer chlorin e6 (Ce6) was loaded in this Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-DOX prodrug nanoparticles for near-infrared fluorescence imaging and combination of chemotherapy and photodynamic therapy against tumor. The nanoparticles exhibited pH-responsive DOX and Ce6 release characteristics, which was caused by the acid-sensitive linker between Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) and DOX. It also demonstrated synergistic effects on cell uptake, cancer cell apoptosis and significant growth suppression in non-small cell lung cancer (A549). Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-PTX conjugate Paclitaxel (PTX) is a BCS class Ⅳ drug with poor solubility and permeability as well as a P-gp substrate, which hinders the effective drug delivery and MDR tumor therapy. Zhang's group 58 synthesized a redox-sensitive prodrug Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-SS-PTX, which could be rapidly dissociated in intracellular redox environment (high GSH concentration) to release PTX for cytotoxicity against tumor and Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) active ingredient for P-gp inhibition. The prodrug can self-assemble to stable micelles and realize the passive tumor targeting through the enhanced permeation and retention (EPR) effect. Compared with non-responsive ester bond conjugated PTX prodrug Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-CC-PTX, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-SS-PTX exhibited better stability and in vitro sustained drug release triggered by intracellular reductive environment. The increased stability of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-SS-PTX micelles may be attributed to the soft sulfurs linker between Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) and PTX in comparison to the only two carbon linker of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-CC-PTX. Compared with the clinical formulation of Taxol® and Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-CC-PTX, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-SS-PTX micelles exhibited increased intracellular PTX accumulation for drug-resistant A2780/T cells, which may be caused by the rapid dissociated Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) from the redox-sensitive prodrug. Rh123 was used as a model drug of P-gp substrate to evaluate the drug retention in MDR tumor. When the cells treated with verapamil or prodrugs, Rh123 fluorescence intensity was increased compared with free Rh123. In particular, much higher fluorescence intensity was exhibited in Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-SS-PTX compared with Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-CC-PTX, which further confirmed the P-gp inhibition property from dissociated Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS). As expected, this functional prodrug micelle increased the cytotoxicity of PTX in A2780/T cells. Compared with the uncleavable Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-CC-PTX prodrug and Taxol®, the stimuli-responsive prodrug reduced the IC50 and increased the apoptosis/necrosis of MDR tumor. In vivo evaluation further demonstrated the potential of this prodrug micelle on cancer treatment as the increased AUC, extended t1/2, enhanced drug distribution in tumor and significant tumor growth inhibition with reduced side effects. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-cisplatin conjugate Cisplatin is widely used in testicular, ovarian, cervical, head and neck, and non-small-cell lung cancers. However, the clinical application is limited for low solubility, nephrotoxicity, severe peripheral neurotoxicity, inherent and acquired drug resistance 59. Feng's group 60 developed Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-cisplatin prodrug to improve the water-solubility and reduce the neurotoxicity of cisplatin. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-cisplatin can self-assemble to micelles with high drug loading capability. The higher cell uptake and cytotoxicity against HepG2 hepatocarcinoma cells were found in Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-cisplatin prodrug compared with free drug. The prodrug micelles also showed significant neuroprotective effects with higher IC50 value for the SH-SY5Y neuroblast-like cells in comparison to free cisplatin. In addition, Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) is a powerful anticancer agent when dealing with breast cancer with high level of human epidermal growth factor receptor 2 (HER2) expression 61. It may be related to the inhibition effect of mitochondrial respiratory complex Ⅱ and the ensuing ROS generation, resulting in cell apoptosis via the HER2 receptor tyrosine kinase signaling pathway 33. Mi and coworkers 62 developed a targeted delivery system of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-cisplatin prodrug nanoparticles for the co-delivery of cisplatin, docetaxel (DTX) and Herceptin for good tumor inhibition in HER2 overexpressed breast cancers. Poly(lactic acid) (PLA)-Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS), Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-COOH and Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-cisplatin were mixed to fabricate nanoparticles for the multimodality treatment of breast cancer. The multidrug-loaded nanoparticles exhibited much lower IC50 value for SK-BR-3 cells with high expression of HER2 compared with the admixture of free drugs. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-5-FU conjugate Liu's group 63, 64 developed multifunctional nanoparticles for co-delivery of hydrophobic drug PTX and hydrophilic drug 5-fluorouracil (5-FU) to overcome MDR. Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-5-FU was synthesized by simply conjugating succinoylated Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) with 5-FU. The nanoparticles, composed of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-5-FU prodrug and PTX, showed enhanced cytotoxicity against MDR tumor compared with individual agent treatment 64. They further developed nanoemulsions with PTX-Vitamin E and Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS)-5-FU prodrug. The nanoemulsions with drugs co-delivery exhibited synergistic effect of overcoming PTX resistance in human epidermal carcinoma cell line KB-8-5 63. The effective anticancer activity was resulted from the P-gp inhibition effect of Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) and the synergistic effect of PTX and 5-FU which can simultaneously target diverse signaling pathways for cancer killing. Targeting ligand conjugated Kolliphor TPGS (VITAMIN E TPGS, E vitamini TPGS) RGD has been applied as a potential targeting ligand in cancer treatment for tumors with αvβ3 integrin receptors overexpression. Li's group 112 formulated PTX and Survivin shRNA co-loaded targeted nanoparticles by mixing Pluronic P85-polyethyleneimine, Kolliphor TPGS (VITAMIN E
KORTACID 1299
Kortacid 1299 is a natural fatty acid that can act as a cleanser and surfactant.
Kortacid 1299 is primarily used in the cosmetics industry as an emulsifier in facial creams and lotions.

CAS Number: 209-647-6.
EC Number: 209-647-6



APPLICATIONS


Kortacid 1299 finds applications in various industries, including:

Cosmetics industry - as an emulsifier in facial creams and lotions
Personal care industry - as a cleanser and surfactant in soaps and toiletries
Pharmaceutical industry - as an ingredient in topical formulations for treating skin diseases
Food industry - as a food additive, mainly as a flavoring agent in baked goods, confectionery, and dairy products
Industrial applications - as a raw material for producing surfactants, detergents, and other chemical products


Overall, Kortacid 1299 is a versatile compound that finds use in various industries due to its emulsifying, cleansing, and surfactant properties.


Kortacid 1299 is commonly used as an emulsifier in the production of cosmetic creams and lotions.
Kortacid 1299 is often added to facial products due to its moisturizing and cleansing properties.

Kortacid 1299 can also be used as a surfactant in the production of soaps and toiletries.
Kortacid 1299 can be used in hair care products as a conditioning agent.

Kortacid 1299 is often used in the production of natural and organic cosmetic products.
Kortacid 1299 is commonly used in the production of personal care products due to its biodegradability.

Kortacid 1299 can be used as a foam booster in the production of shaving creams and foams.
Kortacid 1299 can also be used as a thickener in the production of cosmetic products.
Kortacid 1299 is an effective emulsifying agent in the production of oil-in-water emulsions.

Kortacid 1299 can be used as a lubricant in the production of cosmetic products.
Kortacid 1299 is often added to lipsticks to improve their texture and application.

Kortacid 1299 can be used as a surfactant in the production of household cleaning products.
Kortacid 1299 can be added to laundry detergents as a surfactant and cleaning agent.

Kortacid 1299 is often used in the production of industrial lubricants.
Kortacid 1299 is commonly used in the production of food and pharmaceuticals.

Kortacid 1299 can be used in the production of plasticizers and resins.
Kortacid 1299 can be used in the production of metalworking fluids and cutting oils.
Kortacid 1299 is commonly used as a raw material in the production of other chemicals.

Kortacid 1299 can be used as a dispersing agent in the production of pigments and dyes.
Kortacid 1299 is often added to leather processing agents to improve their performance.

Kortacid 1299 can be used in the production of biodegradable lubricants and hydraulic fluids.
Kortacid 1299 can be used in the production of paints and coatings.

Kortacid 1299 can be used as an emulsifying agent in the production of emulsion polymers.
Kortacid 1299 is often added to adhesive formulations to improve their performance.
Kortacid 1299 can be used in the production of candles as a hardening agent.

Kortacid 1299 is used in the formulation of hair care products such as shampoos and conditioners as a foam booster and thickener.
Kortacid 1299 can be used as a lubricant in the production of various products, including rubber and plastics.

Kortacid 1299 can be used as a raw material for the production of various esters.
Kortacid 1299 is used in the manufacture of surfactants and emulsifiers for various applications.

Kortacid 1299 is used in the production of various personal care products such as bath gels and body washes as a foam booster.
Kortacid 1299 is used in the manufacture of detergents as a surfactant.

Kortacid 1299 is used as a wetting agent and emulsifier in the formulation of insecticides and herbicides.
Kortacid 1299 can be used in the manufacture of textile auxiliaries as a softening agent.

Kortacid 1299 is used in the production of metalworking fluids as a lubricant.
Kortacid 1299 is used in the formulation of leather products such as shoe polishes and leather conditioners as a softening agent.
Kortacid 1299 is used in the production of lubricants as a base oil.

Kortacid 1299 can be used as an emollient in the formulation of cosmetics such as creams and lotions.
Kortacid 1299 is used as a raw material for the production of various fragrances and flavors.

Kortacid 1299 can be used in the formulation of adhesives as a tackifier.
Kortacid 1299 is used in the manufacture of agricultural chemicals as a solvent.

Kortacid 1299 is used in the production of plasticizers as a raw material.
Kortacid 1299 is used as a lubricant in the production of various metal products such as wires and cables.
Kortacid 1299 can be used in the production of candles as a raw material.

Kortacid 1299 is used as a corrosion inhibitor in the production of metal products.
Kortacid 1299 is used in the manufacture of paper and pulp products as a sizing agent.

Kortacid 1299 is used as a raw material for the production of various resins and polymers.
Kortacid 1299 can be used as a flotation agent in the mining industry.

Kortacid 1299 is used in the production of rubber products as a plasticizer.
Kortacid 1299 is used as a mold release agent in the production of various products, including rubber and plastics.
Kortacid 1299 can be used in the formulation of lubricating oils as a viscosity modifier.


As a raw material, Kortacid 1299 can be used in a variety of products across industries.
Some examples of products that may use Kortacid 1299 in their production process include:

Cosmetics, such as facial creams and lotions, as an emulsifier and surfactant
Soaps and toiletries, as a surfactant
Detergents and cleaning products, as a surfactant and cleanser
Food products, as an additive in the production of flavors and fragrances
Pharmaceutical products, as a component in certain drug formulations
Textile industry, as an additive in fabric softeners and other textile treatments
Plastic and rubber industry, as a lubricant and release agent in the production process
Metalworking industry, as a lubricant and corrosion inhibitor in metalworking fluids
Paper industry, as a sizing agent to improve paper strength and stability
Adhesive industry, as a component in certain adhesive formulations
Paint and coatings industry, as a component in certain paint and coating formulations
Agricultural industry, as a component in certain pesticide formulations
Automotive industry, as a component in certain lubricants and additives for engine oils
Construction industry, as a component in certain concrete and mortar formulations
Petroleum industry, as a component in certain drilling muds and fluids.



DESCRIPTION


Kortacid 1299 is a natural fatty acid that can act as a cleanser and surfactant.
Kortacid 1299 is primarily used in the cosmetics industry as an emulsifier in facial creams and lotions.

Due to its biodegradable nature, Kortacid 1299 is a preferred ingredient in eco-friendly cosmetic formulations.
Additionally, Kortacid 1299 can also be used as a surfactant in soaps and toiletries.

Kortacid 1299 is a white, waxy, and odorless solid at room temperature.
Kortacid 1299 is a medium-chain fatty acid with a 12-carbon chain length, specifically lauric acid, with a purity of over 99%.

Kortacid 1299 is insoluble in water but soluble in organic solvents such as ethanol, ether, and chloroform.
Kortacid 1299 has a faint odor and a mild taste, and is often used as a flavoring agent in the food industry.
Kortacid 1299 is readily and rapidly biodegradable, making it an environmentally friendly choice for use in various applications.



PROPERTIES


Molecular formula: C12H24O2
Molecular weight: 200.32 g/mol
Melting point: 44.2 °C (111.6 °F)
Boiling point: 298 °C (568 °F)
Density: 0.89 g/cm³ at 25 °C (77 °F)
Solubility: Soluble in ethanol, ether, chloroform, and benzene, but insoluble in water
Biodegradability: Rapidly and readily biodegradable, making it an environmentally friendly ingredient.



FIRST AID


Inhalation:

Move the person to fresh air.
If the person is not breathing, call for emergency medical attention immediately and administer artificial respiration.
If breathing is difficult, give oxygen.
Get medical attention if symptoms persist.


Skin Contact:

Take off contaminated clothing and shoes immediately.
Wash affected areas thoroughly with soap and plenty of water for at least 15 minutes.
Seek medical attention if irritation or symptoms of an allergic reaction occur.


Eye Contact:

Flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally.
Seek medical attention if irritation or symptoms of an allergic reaction occur.


Ingestion:

Do not induce vomiting.
Rinse mouth with water.
Drink plenty of water.

Seek medical attention immediately.
Never give anything by mouth to an unconscious person.


Note to Physician:

Treat symptomatically.


General Advice:

If you feel unwell, seek medical advice (show the label or SDS where possible).
Ensure that medical personnel are aware of the material(s) involved, and take precautions to protect themselves.
Show this safety data sheet to the doctor in attendance.



HANDLING AND STORAGE


Handling:

Use appropriate protective equipment, such as gloves and safety goggles, when handling Kortacid 1299 to avoid skin and eye contact.
Avoid breathing in the dust or mist of Kortacid 1299, as it may cause respiratory irritation.

Store Kortacid 1299 in a cool, dry, and well-ventilated area away from incompatible substances, such as strong oxidizing agents.
When transferring Kortacid 1299, use closed systems or adequate ventilation to prevent the release of dust or mist.
Avoid generating dust during handling or transfer of Kortacid 1299.


Storage:

Store Kortacid 1299 in a tightly closed container in a cool, dry, and well-ventilated area away from heat, sparks, and flames.
Keep Kortacid 1299 away from sources of ignition, such as open flames and heat sources.
Store Kortacid 1299 separately from strong oxidizing agents and reducing agents.

Do not store Kortacid 1299 near food, feed, or beverages.
Keep Kortacid 1299 in its original container with a tight-fitting lid and store it in a safe location, away from children and pets.



SYNONYMS


Dodecanoic acid
Laurostearic acid
n-Dodecanoic acid
1-Undecanecarboxylic acid
C12:0 (referring to its 12-carbon chain length)
C12 fatty acid (referring to its 12-carbon chain length and fatty acid nature)
Coconut oil acid (since it is a major component of coconut oil)
Dodecanoic acid
Duodecylic acid
C12:0 fatty acid
Coco fatty acid
Cocos nucifera oil
N-dodecanoic acid
Laurostearic acid
Vulvic acid
Lauroic acid, zinc salt
Lauroic acid, lithium salt
Lauroic acid, sodium salt
Lauroic acid, potassium salt
Lauroic acid, magnesium salt
Lauroic acid, calcium salt
1-dodecoic acid
Dodecoic acid
Dodecylenic acid
n-Lauroic acid
Lipoic acid
Laurinsäure (German)
Acide laurique (French)
Acido laurico (Italian, Spanish)
Lauric acid, coconut oil
Lauric acid, palm oil
Lauric acid, animal fats
Univol U-215
Cerasynt L 30
Prifac 2954
Pelemol LA
Cithrol 10MSA
NAA 50
Coco nut oil fatty acid
Coco palm kernel oil fatty acid
Coco butter fatty acid
Coco lauric acid
Decanoic acid
Dodecoic acid
Dodecylic acid
Hydrofol acid 1299
Hydrofol acid 1299P
Kortacid 1299LA
Laurex 1299
Lauric acid, coconut oil fatty acid
NAA C-50
NAA L-50
Lauric acid (natural)
KOSTERAN-S3 G
KOSTERAN-S/3 G IUPAC Name [2-(4-hydroxy-3-octadecanoyloxyoxolan-2-yl)-2-octadecanoyloxyethyl] octadecanoate KOSTERAN-S/3 G InChI=1S/C60H114O8/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-43-46-49-56(62)65-53-55(67-57(63)50-47-44-41-38-35-32-29-26-23-20-17-14-11-8-5-2)60-59(54(61)52-66-60)68-58(64)51-48-45-42-39-36-33-30-27-24-21-18-15-12-9-6-3/h54-55,59-61H,4-53H2,1-3H3 KOSTERAN-S/3 G InChI Key IJCWFDPJFXGQBN-UHFFFAOYSA-N KOSTERAN-S/3 G Canonical SMILES CCCCCCCCCCCCCCCCCC(=O)OCC(C1C(C(CO1)O)OC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC KOSTERAN-S/3 G Molecular Formula C60H114O8 KOSTERAN-S/3 G CAS 26658-19-5 KOSTERAN-S/3 G EC Number 247-891-4 KOSTERAN-S/3 G E number E492 (thickeners, ...) KOSTERAN-S/3 G Molar mass 963.54 g/mol KOSTERAN-S/3 G Appearance Waxy solid KOSTERAN-S/3 G Physical Description Liquid; OtherSolid KOSTERAN-S/3 G Form Hard, waxy solid KOSTERAN-S/3 G Colour Light cream to Tan KOSTERAN-S/3 G Acid Value Max 7 mgKOH/gm KOSTERAN-S/3 G Saponification Value 176-188 mgKOH/gm KOSTERAN-S/3 G Moisture content Max 1% KOSTERAN-S/3 G Hydroxyl Value 66-80 mgKOH/gm KOSTERAN-S/3 G Heavy Metals (as Pb) Less than 10mg/kg KOSTERAN-S/3 G Arsenic Less than 3 mg/kg KOSTERAN-S/3 G Cadmium Less than 1mg/kg KOSTERAN-S/3 G Mercury Less than 1 mg/kg KOSTERAN-S/3 G Molecular Weight 963.5 g/mol KOSTERAN-S/3 G XLogP3-AA 24.3 KOSTERAN-S/3 G Hydrogen Bond Donor Count 1 KOSTERAN-S/3 G Hydrogen Bond Acceptor Count 8 KOSTERAN-S/3 G Rotatable Bond Count 56 KOSTERAN-S/3 G Exact Mass 962.851371 g/mol KOSTERAN-S/3 G Monoisotopic Mass 962.851371 g/mol KOSTERAN-S/3 G Topological Polar Surface Area 108 Ų KOSTERAN-S/3 G Heavy Atom Count 68 KOSTERAN-S/3 G Formal Charge 0 KOSTERAN-S/3 G Complexity 1100 KOSTERAN-S/3 G Isotope Atom Count 0 KOSTERAN-S/3 G Defined Atom Stereocenter Count 0 KOSTERAN-S/3 G Undefined Atom Stereocenter Count 4 KOSTERAN-S/3 G Defined Bond Stereocenter Count 0 KOSTERAN-S/3 G Undefined Bond Stereocenter Count 0 KOSTERAN-S/3 G Covalently-Bonded Unit Count 1 KOSTERAN-S/3 G Compound Is Canonicalized Yes Kosteran-S/3 G is composed of Sorbitan Tristeareate. It functions as a W/O-emulsifier. This product is suitable for skin care creams and lotions, natural care, and colour cosmetics.KOSTERAN-S/3 G is a nonionic surfactant. It is variously used as a dispersing agent, emulsifier, and stabilizer, in food and in aerosol sprays. As a food additive, it has the E number E492. Brand names for polysorbates include Alkest, Canarcel, and Span. The consistency of KOSTERAN-S/3 G is waxy; its color is light cream to tan.KOSTERAN-S/3 G , also known as E492 or sorbester P38, belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups. KOSTERAN-S/3 G is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, KOSTERAN-S/3 G is primarily located in the membrane (predicted from logP).KOSTERAN-S/3 G is a nonionic surfactant. It is variously used as a dispersing agent, emulsifier, and stabilizer, in food and in aerosol sprays. As a food additive, it has the E number E492. Brand names for polysorbates include Alkest, Canarcel, and Span. The consistency of KOSTERAN-S/3 G is waxy; its color is light cream to tan.Pernetti et al. (2007) showed the structuring of edible oils using a mixture of sunflower lecithin and KOSTERAN-S/3 G (STS). Individually, neither of these components was by itself capable of inducing gelation even at concentrations as high as 20% w/w. However, when a mixture was used, structuring was achieved at concentrations of approximately 4% w/w. The mixture composition that resulted in structuring ranged between 2:3 lecithin:KOSTERAN-S/3 G to 3:2 lecithin:KOSTERAN-S/3 G . Microscopy of the gels showed the presence of needle-like crystals with lengths of approximately 10 μm. Preparations of only KOSTERAN-S/3 G in oil also showed the presence of crystalline particles, although these crystals had a lower aspect ratio (less needle-like) than when lecithin was present in the mixture. Lecithin was surmised to modify the crystal habit of the KOSTERAN-S/3 G crystals such that a more needle-like morphology resulted, which is more efficient at structuring oil. However, these gels melted at a low temperature (approximately 15°C) and were very sensitive to the addition of water, both of which would limit their utility in water-rich foods.Individually both lecithin (Lec) and KOSTERAN-S/3 G (STS) are incapable of forming oil gels at concentration between 6 and 20 %wt in absence of a polar solvent. However, when mixed in specific ratios between 40:60 to 60:40, Lec:KOSTERAN-S/3 G can form firm gels at a total concentration as low as 4 %wt (Pernetti et al., 2007). The crystalline units formed in these systems are based on KOSTERAN-S/3 G , while Lec plays an important role in influencing both the morphology of the crystalline units as well as the network junctions among the formed units. The gel however has limited use as hardstock fat replacer as it starts softening at temperature above 15 °C and undergoes complete collapse at 30 °C (Pernetti et al., 2007).In chocolate formulations surface-active substances are often used, for instance to reduce viscosity. Popular additives are KOSTERAN-S/3 G (STS), sorbitan monoesters, lecithin, mono- and diacylglycerols. Since roughly two-thirds of the chocolate recipe contains non-fat-soluble substances such as sugar and cocoa powder, the lecithin acts as a lubricant. The polar part of the lecithin covers the sugar particles, while the hydrophobic part faces the fat phase. Roughly 0.5 % is needed to cover the sugar and cocoa powder particles. The covered particles reduce the viscosity of the chocolate mass which is favourable. Lecithin itself is known to reduce the crystallization rate of fat indicating that the amount of lecithin should be controlled (Guth et al., 1989). Diacylglycerols also have a negative effect on the crystallization rate and on polymorphic transformation. However, there are several types of diacylglycerols each with different properties (Siew and Ng, 2000). For instance, it has been shown that 1.3-dipalmitin increases the melting point of the palm oil while 1.2-dipalmitin decreases the melting point.KOSTERAN-S/3 G is a component often used in CBR and CBS applications to stabilize β′ crystals (Wilson, 1999). It is shown to be one of the most effective emulsifiers for improving both initial gloss as well as bloom stability (Weyland, 1994). However, KOSTERAN-S/3 G also seems to have a negative effect on crystallization rate in these applications. Sorbitan monoesters and monoacylglycerols improve the crystallization rate in CBR and CBS systems because they are insoluble in the fat phase and act as nucleation agents. However, bloom stability does not seem to improve.In summary, the minor components in a fat play a crucial part in fat crystallization, yet there is inadequate understanding of the mechanisms behind their influence. The reason is that the levels are low and individual components often influence each other.KOSTERAN-S/3 G is a component often used in CBR and CBS applications to stabilize β′ crystals (Wilson, 1999). It is shown to be one of the most effective emulsifiers for improving both initial gloss as well as bloom stability (Weyland, 1994). However, KOSTERAN-S/3 G also seems to have a negative effect on crystallization rate in these applications.Lipophilic emulsifiers in the form of KOSTERAN-S/3 G (STS) are used as crystal-modifying agents in fats, where they prevent the formation of the high-melting β-crystal. The function of KOSTERAN-S/3 G is assumed to be due to its ability to co-crystallise with triacylglycerides in the β'-crystal form, preventing a solid-state crystal transition to the higher-melting β-crystal form during storage.7 Other emulsifiers, such as LACTEM or CITREM, provide a similar crystal-modifying function in cocoa butter substitutes (CBS) or cocoa butter replacers (CBR), but are less efficient than KOSTERAN-S/3 G .In the case of the transition from beta (V) into beta (VI), there are a number of possibilities. KOSTERAN-S/3 G (used to inhibit bloom in CBR and CBS systems as well) and similar emulsifiers reportedly slow the polymorphic transformation (Garti et al., 1986). If the desire is to avoid unnecessary items on the label, TAG solutions exist. Milk fat is well known for its bloom inhibiting effect; dark chocolate often has a small amount of milk fat added for this reason. More effective are bloom retarding fats that incorporate saturated TAG having mixed long (C16, C18) and medium (C10-C14) chain fatty acids (Cain et al., 1995). Thus, they are a specific type of lauric fat. They are stable in the beta′ polymorph.KOSTERAN-S/3 G (abbreviation STS), also known as Span 65, a nonionic surfactant that can be used as an emulsifier and stabilizer in food with the European food additive number E492. Its main functions are to retard fat bloom in chocolates and prevent cloudy appearance in cooking oils.Vegetable sourced stearic acid is the most used in the manufacturing process of KOSTERAN-S/3 G and other sorbitan esters of fatty acids. KOSTERAN-S/3 G is used as a water in oil (W/O) emulsifier and when used in combination with polysorbates they can stabilize oil in water (O/W) emulsions. The formulation of the Span/Polysorbate ratio can produce emulsifying systems with various HLB values. KOSTERAN-S/3 G is mainly used as an anti-bloom agent of fat, and also maintains the color and gloss in chocolates.KOSTERAN-S/3 G and lecithin are often used as surface-active substances to reduce viscosity in chocolate formulations. In chocolate, KOSTERAN-S/3 G adjusts sugar crystallization and appearance, also it can reduce stickiness.KOSTERAN-S/3 G is used as an emulsifier that can be used to retard fat bloom by preventing β’ crystals from converting to β crystals when exposed to excessive heat conditions, which tend to migrate to the chocolate surface and thus cause fat bloom. KOSTERAN-S/3 G can be used as an anti-crystallization agent in cooking oils (e.g. palm oil, coconut oil) to prevent oils cloudy appearance which are formed by harden-fast fractions under colder temperatures. KOSTERAN-S/3 G functions as a surfactant in cosmetics and personal care products. Its concentrations typically range between 0.1% and 5% (up to 10%). KOSTERAN-S/3 G has almost no side effects when used as a food additive. It is approved as an indirect food additive by the FDA.Yes, KOSTERAN-S/3 G would be halal, kosher and vegan if the raw material – stearic acid is from natural vegetable oils. However, some manufacturing processes may use stearic acid from animal fats and oils.KOSTERAN-S/3 G is used as an emulsifier and stabiliser. It is produced by the esterification of sorbitol with commercial stearic acid derived from food fats and oils.It is a mixture of the partial esters of sorbitol and its mono- and dianhydride with edible stearic acid.KOSTERAN-S/3 G is produced by the esterification of Sorbitol with commercial edible fatty acids and consists of approximately 95% of a mixture of the esters of Sorbitol and its mono and di-anhydrides.KOSTERAN-S/3 G is an effective emulsifier to retard fat bloom in chocolate. Fat used in chocolate, particularly cocoa butter, forms as a tightly packed β’ polymorph/crystal which is an unstable crystal but is vital for the functional and aesthetic quality of chocolate. If chocolate is not tempered properly or is exposed to excessive heat, these β’ crystals convert to β crystals which are less tightly packed but are more stable. These β crystals tend to migrate to the surface causing fat bloom to occur and also having a negative impact on the aesthetics of the chocolate.KOSTERAN-S/3 G ’s structure mimics the β’ crystals and bonds with such fat crystals and retards their conversion to the less desirable β crystals.KOSTERAN-S/3 G is used as a crystal inhibitor in oils which contain fractions that harden faster during colder temperatures making the oils look cloudy. This cloudy oil is perceived by many as deteriorated oil which it actually is not. It is just aesthetically unacceptable.The addition of KOSTERAN-S/3 G retards the harder fractions from nucleating at lower temperatures and causing cloudiness in oils.KOSTERAN-S/3 G has a structure more similar to a triglyceride than to an emulsifier.KOSTERAN-S/3 G has a structure more similar to a triglyceride than to an emulsifier.In 1947, Krantzconducted life-span studies with Sorbitan palmitate, Sorbitan stearate, KOSTERAN-S/3 G , and Sorbitan oleate. The study reports were only available as secondary source and therefore very limited in documentation of examinations and results. In each study, 30 male rats were exposed to a dietary concentration of 5% test substance in their daily diet, corresponding to 5000 mg/kg bw/d (calculation based on the assumption of an average body weight of 200 g and a daily average food consumption of 20 g). No treatment-related mortality or clinical signs as well as effects on body weights and histopathology were observed. Therefore, a NOAEL of≥5000 mg/kg bw/day was determined for Sorbitan palmitate, Sorbitan stearate, KOSTERAN-S/3 G , and Sorbitan oleate. Likewise, Sorbitan laurate was tested: male rats were fed the test substance in diet for 20.5 months at 5% and for 2 years at 10%, corresponding to 5000 and 10000 mg/kg bw/day (calculation based on the assumption of an average body weight of 200 g and a daily average food consumption of 20 g) (Barboriak 1970). Diarrhea and retarded growth were observed in the animals of the 10% dose group. No effects were observed at histopathology, therefore, a NOAEL was therefore set at 5000 mg/kg bw/d. The same NOAEL was determined in a second chronic study with rats that were fed 5% of the test substance in diet for 2 years (Krantz 1970). Again, no clinical signs were observed and mortality, body weight gain, haematology and histopathology were unaffected.
KRILL OIL
Krill oil is a substance obtained from the sea creature called "Euphausia superba" that lives in the oceans.
Krill oil contains a high amount of Omega 3 fatty acids, and these fatty acids are in the form of phospholipids.
Additionally, Krill Oil is a dietary supplement containing astaxanthin, vitamin A and vitamin E.


SYNONYMS:
Aceite de Krill, Acide Docosahexaénoïque, Acides Gras Oméga 3, Acides Gras N-3, Acides Gras Polyinsaturés, Acides Gras W3, Antarctic Krill Oil, Concentré de Protéines Marines, DHA, Docosahexanoic Acid, EPA, Euphausia Superba Oil, Euphausiacé, Euphausiids Oil, Huile d' Euphausia Superba, Huile de Krill, Huile de Krill Antarctique, Huile d'Oméga 3, Marine Protein Concentrate, n-3 Fatty Acids, Omega 3, Omega-3 Fatty Acids, Omega-3, Oméga 3, Omega-3 Fatty Acids, Omega-3 Oil, Polyunsaturated Fatty Acids, W-3 Fatty Acids



Astaxanthin is a substance with strong antioxidant properties.
Omega 3 fatty acid supplements; It is known to be important in mental development, hyperlipidemia, premenstrual syndromes, inflammatory and cardiological diseases.


Omega-3 fatty acids, which nourish and support the building blocks of our body, cannot be produced by the body.
Omega-3 deficiency can manifest itself in many different ways, especially in productivity and quality of life .
At this point, you may want to use nutritional supplements for a body whose needs are met from head to toe.


Although most of the nutritional supplements containing omega-3 are produced from fish oil, it is now possible to find different sources of omega-3.
Krill oil comes from krill, tiny shrimp-like creatures that live in very cold ocean waters.
Studies show that krill oil might have health benefits similar to those of fish oil.


Shrimp-like crustaceans from the Euphausiacea family are generally called 'Krill' and consist of 86 species.
Euphausia superba, also known as the “Antarctic Krill,” is the most common Krill species in the pristine oceans surrounding Antarctica.
They are at the bottom of the food chain because they feed many marine creatures.


Krill oil, like fish oil, contains omega-3 acids EPA and DHA.
However, krill oil and fish oil differ in the chemical structures of the fatty acids they contain.
Unlike the bright golden yellow color of fish oil that we are used to, krill oil has a red tone color.


Krill oil owes its unique red color to a natural antioxidant it contains.
Krill oil also fights against free radicals with its natural antioxidant content.
Krill oil is the oil of the shellfish, also known as Antarctic krill.


Krill Oil also contains EPA and DHA fatty acids.
Due to its structure, Krill Oil is red in color.
Krill oil can be taken as a supplement when necessary.


Krill Oil is a source of Omega 3 in phospholipid form.
Krill oil is one of the most powerful antioxidants in nature with its natural astaxanthin content.
In addition, risks such as leakage, explosion and oxidation have been minimized with Licaps (liquid capsule) technology, which is produced using fish gelatin.


Krill oil is an oil obtained from a small, shrimp-like, aquatic sea creature called euphausia superba, which contains omega 3 fatty acids.
Krill oil, which offers many health benefits as it contains omega 3 fatty acids, reduces inflammation and relieves arthritis and joint pain, as well as being a powerful source of antioxidants.


Due to these properties, krill oil is also considered as an alternative to fish oil.
Krill is a shrimp-like crustacean.
Krill oil, unlike fish oil, has a phospholipid structure and contains "astaxanthin"


Krill oil, an alternative to fish oil , is rich in omega 3 fatty acids.
Although krill oil and fish oil both contain two omega 3 fatty acids, docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), the omega 3 fatty acids found in krill oil are considered to have a higher bioavailability and absorption rate in the body than fish oil.


Krill oil is an extract prepared from a species of Antarctic krill, Euphausia superb.
Processed krill oil is commonly sold as a dietary supplement.
Krill oil, rich in Omega 3 fatty acids, is an oil obtained from a small sea creature called Euphausia superb.


Two components of krill oil are omega-3 fatty acids similar to those in fish oil, and phospholipid-derived fatty acids (PLFA), mainly phosphatidylcholine (alternatively referred to as marine lecithin).
Fishing for krill where previously the focus was on marine life of higher trophic level is an example of fishing down the food web.


While the word krill means “small fish” in Norwegian, the tiny crustaceans pack a big punch with their sources of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), two omega-3 fatty acids only found in marine life.


Krill Oil contains high levels of eicospentanoic acid (EPA) and docosahexaenoic acid (DHA) also known as long-chain omega 3 fatty acids which is essential for good health.
Krill Oil contains the beneficial omega-3 fatty acids EPA and DHA, and a good level of the sought after astaxanthin.


The EPA and DHA in krill oil are bound to phospholipids, which means they are rapidly and readily uptaken into cell membranes, more efficiently than EPA and DHA on triglyceride carriers, such as in fish oils.
Krill Oil is a source of fatty acids that helps to maintain normal blood pressure and heart health.


Krill is a small crustacean with an appearance similar to shrimp.
They are found in the colder waters of the ocean.
Krill primarily serve as a food source for other animals in the ocean, for example - whales, seals, penguins, squid and fish.


Krill is found in the oceans off of Antarctica, Canada, and Japan.
Harvesting of krill is controversial.
There is concern that commercial harvesting of Krill for use in Krill Oil supplements could threaten the species that consume it for food, including whales.


All krill oil sold in nutritional supplements is harvested out of the open ocean, upsetting the natural balance of food supplies for larger marine animals.
Commercial uses of Krill include salmon aquaculture farming, harvesting for use in Krill Oil capsules, as food for home aquariums, and as a human food source.


Krill, known as Okiami has been harvested by the Japanese as a human food source since the 19th century, and is also consumed in South Korea and Taiwan.
Krill has a pink or red appearance due to the plankton that they consume as a food source in the ocean.
Krill Oil is derived from Antarctic krill, small shrimp-like creatures that thrive in the frigid waters of the Southern Ocean.


These minuscule crustaceans form a crucial part of the marine food chain, serving as a primary food source for various marine species, including whales, seals, and penguins.
Krill oil, rich in Omega 3 fatty acids, is an oil obtained from a small sea creature called Euphausia superb.



USES and APPLICATIONS of KRILL OIL:
Krill Oil is an astaxanthin-derived supplement containing 1000 mg of krill oil obtained from a small shrimp-like shellfish that lives in the oceans.
Krill Oil offers high bioavailability due to its phospholipid omega 3 structure.
Krill Oil is recommended to consume 2 capsules a day for adults.


A unique formula extracted from Antarctic Krill to deliver essential omega-3 (EPA & DHA), choline, phospholipids and astaxanthin with proven effects to improve human health.
Krill Oil has also been used to treat high blood pressure, stroke, cancer, osteoarthritis, depression and premenstrual syndrome (PMS), although high quality studies with adequately sized populations validating these uses are lacking.


Krill Oil may also be used for purposes not listed in this medication guide.
Krill Oil is obtained through a meticulous extraction process that ensures the preservation of its potent nutritional profile, making it a valuable addition to the realm of dietary supplements.



BENEFITS OF KRILL OIL:
1. Krill Oil provides a Rich Source of Omega-3:
Omega-3 fatty acids, which cannot be produced by our body, are important for individuals of all ages, from 7 to 70.
You can choose fish oil supplements to meet your DHA and EPA needs, with benefits ranging from muscle development to skin beauty.

However, krill oil appears as a unique option for those who cannot consume fish oil due to complaints such as fishy smell and indigestion.
Additionally, research shows that the fatty acids contained in krill oil are more easily absorbed by the body than fish oils.
Krill oil, in phospholipid form, can be easily absorbed by the body and used more effectively.


2. Krill Oil supports the Healing of Inflammatory Diseases:
Compared to marine omega-3 products, krill oil provides higher protection against inflammatory diseases due to its easy absorption.
There are important studies showing that the natural antioxidant called axanthaxin contained in krill oil is a powerful anti-inflammatory.
With this feature, krill oil can help reduce inflammation and have positive effects on rheumatoid arthritis and joint pain.


3. Krill Oil helps Control Cholesterol:
Experts often emphasize the positive effect of omega-3 fatty acids against cardiovascular diseases.
Today, there are studies showing that krill oil is more effective than fish oil in reducing triglycerides and LDL cholesterol, known as bad cholesterol.
Similarly, krill oil may help reduce the risks of heart disease with its positive effects on insulin resistance.


4. Krill Oil supports Anti-Aging Fight with Antioxidant Content:
Supports Anti-Aging Fight with Antioxidant Content:
Antioxidants protect our body by fighting against free radicals that cause cell aging.

Free radicals can cause signs of premature aging, such as loss of elasticity on the skin surface.
Vitamins A and E contained in krill oil help maintain skin beauty and improve its general appearance.


5. Krill Oil helps Reduce PMS (Premenstrual Syndrome) Symptoms:
Research also reveals that omega-3 fatty acids have pain-relieving properties.
Studies on improving PMS symptoms have shown that krill oil may be more effective than other omega-3 sources.
Krill oil can significantly reduce painkiller use in women diagnosed with PMS.


6. Krill Oil supports the Immune System
Regular omega-3 intake is essential for a strong immune system. Krill oil, which can be easily absorbed by the intestine in its phospholipid form, supports the immune system.

Krill oil helps strengthen the immune system against diseases that increase as a result of the slowing down of the body's defense mechanism, especially during seasonal transitions.
In regular use, Krill Oil supports the body in having a more vigorous and healthy immune system.

As with all nutritional supplements, do not forget to consult your doctor before using nutritional supplements containing krill oil.
If you are allergic to any shellfish, do not use supplements containing krill oil without expert advice.



FEATURES OF KRILL OIL:
*Omega 3 in phospholipid form rich in DHA and EPA
*Formula with high bioavailability
*Free of sweeteners, lactose and gluten



ABOUT KRILL OIL:
•Krill is a small, shrimp-like shellfish and is found in all the world's oceans.
They live in flocks and feed on phytoplankton, which is a high source of Omega 3, to survive.

•These creatures feed only on microscopic algae; Due to their small size, short lifespan and diet, they do not accumulate toxins and heavy metals in their bodies.

•Krill Oil contains Superba Boost as a patented raw material and is obtained from Euphausia Superba, also called Antarctic Krill.

•Superba Boost uses Flexitech, a patented technology developed specifically for krill, to obtain high concentrations of active ingredients and to remove any unwanted content.

•Krill oil contains Omega 3 together with choline in phospholipid form.
Phospholipids are the building blocks of our cells and ensure the integrity and flexibility of our cell membranes.

•Krill oil also contains astaxanthin, one of the most powerful antioxidants in the world, in its natural structure.



WHICH DISEASES DOES KRILL OIL BENEFIT?
Research into the potential health benefits of Krill Oil spans a broad spectrum of diseases and conditions, showcasing its versatility as a therapeutic agent.
Some of the notable areas where Krill Oil has shown promise include:


*Cardiovascular Health:
The omega-3 fatty acids EPA and DHA present in Krill Oil have been extensively studied for their cardioprotective effects.

These fatty acids help reduce triglyceride levels, lower blood pressure, improve endothelial function, and decrease the risk of thrombosis, thereby promoting overall cardiovascular health and reducing the incidence of cardiovascular events such as heart attacks and strokes.


*Joint Health:
The anti-inflammatory properties of Krill Oil, attributed to its omega-3 fatty acids and astaxanthin content, make it a promising adjunctive therapy for managing inflammatory joint conditions such as rheumatoid arthritis and osteoarthritis.

By modulating inflammatory pathways and attenuating joint inflammation, Krill Oil may help alleviate pain, improve joint function, and enhance overall quality of life for individuals living with these debilitating conditions.


*Cognitive Function:
Omega-3 fatty acids, particularly DHA, are essential components of brain cell membranes and play crucial roles in neurotransmission, synaptic plasticity, and cognitive function.

Studies suggest that regular consumption of Krill Oil may support brain health and cognitive function, reducing the risk of cognitive decline and age-related neurodegenerative disorders such as Alzheimer's disease.


*Skin Health:
The antioxidant properties of astaxanthin, coupled with the anti-inflammatory effects of omega-3 fatty acids, make Krill Oil a promising agent for promoting skin health and combating various dermatological conditions.

Astaxanthin protects skin cells from oxidative damage induced by UV radiation, while omega-3 fatty acids help maintain skin barrier function, reduce inflammation, and support overall skin hydration and elasticity.


*Women's Health:
Krill Oil may offer unique benefits for women's health, particularly during pregnancy and menopause.
Omega-3 fatty acids play critical roles in fetal development, supporting healthy brain and eye development in the developing fetus.

Additionally, Krill Oil may help alleviate symptoms of menopausal transition, such as hot flashes and mood disturbances, due to its hormonal balancing and anti-inflammatory effects.



BENEFITS OF KRILL OIL:
Krill Oil is also possible to explain the details of the benefits of krill oil as follows:

*Krill oil is a powerful source of antioxidants

*Krill oil, which carries the potential benefits of both fish oil and omega 3, stands out as a powerful source of antioxidants.
These powerful antioxidants play an effective role in fighting free radicals in the body.


*Krill Oil reduces inflammation thanks to Omega 3 and astaxanthin:
Krill oil has a reducing effect on inflammation and inflammation in the body, thanks to the omega 3 and astaxanthin it contains.
Astaxanthin is also considered to have anti-inflammatory and antioxidant benefits that can help combat the negative effects of free radicals on the brain and nervous system.


*Krill oil reduces arthritis and joint pain:
Studies have shown that arthritis and joint pain decrease in people who use krill oil.


*Krill oil supports heart health
Krill oil is a form of oil that supports heart health as it is an effective source of reducing total cholesterol and triglycerides.
At the same time, krill oil can increase levels of good cholesterol, known as HDL .


*Krill Oil lowers bad cholesterol:
Offering many health benefits, krill oil can also prevent some possible diseases, especially heart diseases, by lowering bad cholesterol.


*Krill Oil helps build a healthy immune system
Rich in antioxidants, containing omega 3 fatty acids, reducing inflammation in the body and lowering bad cholesterol levels, krill oil helps create a healthy immune system.


*Krill Oil can reduce anxiety levels
Since it is evaluated that there is a connection between the intake of Omega 3 and the decrease in anxiety level, it is evaluated that krill oil may also be effective in reducing anxiety.


*Krill Oil is a source of vitamins A and E.
Krill oil also offers effective benefit potential, especially for eye health, thanks to the vitamins A and E it contains.



WHAT ARE THE BENEFITS OF KRILL OIL?
The nutritional profile of Krill Oil makes it a veritable treasure trove of health-enhancing compounds.
Krill Oil's most notable constituents include omega-3 fatty acids, specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which play pivotal roles in various physiological processes.

These fatty acids are renowned for their anti-inflammatory properties, which can help alleviate symptoms associated with conditions such as arthritis and promote cardiovascular health by reducing the risk of coronary artery disease and supporting optimal lipid profiles.

Additionally, Krill Oil boasts a potent antioxidant arsenal, including astaxanthin, a carotenoid pigment responsible for the vibrant red hue of krill and various marine organisms.

Astaxanthin exhibits exceptional antioxidant activity, scavenging free radicals and combating oxidative stress, thereby protecting cells from damage and promoting overall health and longevity.



HOW IS KRILL OIL CONSUMED?
Krill Oil is predominantly available in the form of softgel capsules, which are encapsulated to preserve the integrity of the oil and enhance its shelf life.
These capsules are designed for oral consumption, offering a convenient and hassle-free way to incorporate Krill Oil into your daily regimen.
The softgel form also ensures easy digestion and absorption, minimizing any potential discomfort often associated with consuming fish oil supplements.



HOW MUCH KRILL OIL SHOULD BE CONSUMED DAILY?
Determining the optimal dosage of Krill Oil is essential to maximize its health benefits while minimizing the risk of adverse effects.
While individual requirements may vary based on factors such as age, gender, and overall health status, a general guideline suggests a daily intake of 1 to 3 grams of Krill Oil.
However, it is crucial to consult with a qualified healthcare professional to assess your specific needs and tailor the dosage accordingly.



KEY BENEFITS OF KRILL OIL:
*Source of the omega-3 fatty acids EPA and DHA
*Supports heart and brain health
*Anti-inflammatory; supports joint health
*Source of the antioxidant astaxanthin



KRILL OIL ALSO CONTAINS:
*Phospholipid-derived fatty acids (PLFA), which may result in better absorption, and marine lethicin
*A carotenoid antioxidant called astaxanthin.
Antioxidants inhibit oxidation and may neutralize the oxidant effect of free radicals and other substances in body tissues that may lead to disease.



BENEFITS OF KRILL OIL:
Studies have shown krill oil may have a variety of health benefits.
Here are some possible ways it can help you.

*Krill Oil may help your heart
Research shows that krill oil may be effective in reducing total cholesterol and triglycerides.
It may also increase HDL (good) cholesterol levels.

*Krill Oil may reduce inflammation
Research shows that omega-3 fatty acids, which are found in krill oil, may decrease blood pressure in some individuals.

Krill oil also contains astaxanthin, a pigment that’s found in carotenoids (it’s also what gives salmon its pink-red color).
Astaxanthin has been shown to also have anti-inflammatory and antioxidant benefits, which may help fight the negative effects of free radicals on your brain and nervous system.

*Krill Oil may reduce arthritis and joint pain
Another study examined how krill oil may reduce the symptoms of rheumatoid arthritis.
Those who took 300 milligrams of krill oil each day for 30 days saw an improvement in symptom reduction and used less rescue medication.

*Krill Oil can also help with pain.
A small study gave participants with mild knee pain krill oil for 30 days.
The results showed a significant reduction in pain while they were standing or sleeping.

*Krill Oil may help with PMS symptoms
For those who deal with PMS, using krill oil may help alleviate period pain and other symptoms.
A study compared fish oil to krill oil and while both supplements improved symptoms for those with PMS, the individuals taking krill oil needed less pain medication.



KRILL OIL CONTAINS:
Krill oil contains a natural combination and concentration of the following four key nutrients: Omega-3 (EPA & DHA), Phospholipids, Choline, Astaxanthin

*Brain:
Phospholipids assist in the transportation of omega-3 DHA across the blood-brain barrier.

*Heart:
Krill oil has been shown to lower fasting triglycerides which are a risk factor for cardiovascular disease.

*Liver:
Choline and omega-3s are important for maintaining healthy liver function and aid fat metabolism.

*Eyes:
Omega-3s are especially important to help keep your eyes healthy, with the highest concentration of DHA in the body found in the retina.

*Skin:
Omega-3s play a role in modulating the hydration and elasticity of the skin.

*Joints:
Omega-3s play an important role in regulating inflammation in the body, which can have a crucial impact in protecting our joints throughout life.



FEATURES OF KRILL OIL:
Krill is a tiny crustacean that is best known as a significant source of omega 3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
These fatty acids contribute to a healthy heart, mind and body.

They have many roles in the body, including:
*Being raw materials for building cell membranes (DHA is particularly important for retina, brain and sperm cells)
*Making eicosanoids - signalling molecules that direct traffic in the world of inflammation, cardiovascular and lung function, and the immune and endocrine systems
*Specifically, helping to lower blood triglycerides and reducing the risk of blockages linked to heart disease
*Providing a source of energy


Krill oil also contains phospholipids.
Phospholipids, like phosphatidylcholine, are an important component of all our cell membranes, and are particularly important in brain cells and cell communication.

When attached to omega 3 fatty acids like in krill oil, phospholipids are responsible for carrying the fatty acids into cells and significantly increase the potency and bioavailability of both EPA and DHA.
This allows us to take less krill oil to get the same benefit as a higher amount of fish oil.

Antarctic krill, like that found in Organika’s Krill Oil, is also rich in the natural antioxidant astaxanthin.
The deep red colour of each capsule is due to this astaxanthin content.

Recognized for the health-promoting suppression of free radicals, astaxanthin helps to keep the oil fresh and protects the omega-3 fatty acids from oxidation and going rancid.
This means no additives are necessary to maintain the long-term stability of the oil.



WHAT ARE THE BENEFITS OF KRILL OIL?
Krill oil contains fatty acids similar to fish oil and is a rich source of omega 3, supports immunity thanks to the antioxidant astaxanthin , can help reduce inflammation as well as arthritis and joint pain, and protects heart health.

Krill oil benefits can be listed as follows:
*Krill oil is a powerful source of antioxidants.
*Krill Oil strengthens immunity and protects the body against free radicals.
*Krill Oil reduces inflammation thanks to Omega 3 and astaxanthin.
*Krill oil may reduce arthritis and joint pain
*Krill Oil supports heart health.
*Krill Oil lowers bad cholesterol.
*Krill Oil helps build a healthy immune system.
*Krill Oil can reduce anxiety levels.
*Krill oil contains vitamins A and E.



HOW MUCH KRILL OIL SHOULD YOU TAKE?
Since krill oil is not an established treatment, there's no standard dose.
Talk to your healthcare provider to see if krill oil is right for you.



CAN YOU GET KRILL OIL NATURALLY FROM FOODS?
The only source of krill oil is krill.



DIFFERENCE BETWEEN KRILL OIL AND FISH OIL:
Krill oil and oceanic fish oil are rich in omega-3 fatty acids, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
While both contain some EPA and DHA as free fatty acids, krill oil contains particularly rich amounts of choline-containing phospholipids and a phosphatidylcholine concentration of 34 grams per 100 grams of oil.

Krill oil also contains appreciable content of astaxanthin at 0.1 to 1.5 mg/ml, depending on processing methods, which is responsible for its red color.
While fish oil is generally golden yellow in colour, krill oil tends to be reddish.
Krill Oil is generally more expensive to buy as compared to fish oil.



WHAT IS IN KRILL OIL?
Krill contains an oil that is similar to the oils found in fish oils, the omega-3 fatty acids.
Omega-3 fatty acids are recommended for use in lowering triglyceride levels.
Krill Oil use as a supplement to lower blood lipids is increasing in popularity.



KRILL OIL CONTAINS:
The omega-3 polyunsaturated fatty acids EPA (Eicosapentaenoic Acid) and DHA (Docosahexaenoic).
Omega-3 polyunsaturated fatty acids are also found in oils from certain types of fish, vegetables, and other plant sources.
Unlike fish oil, the omega-3 fatty acids in Krill oil are absorbed and carried to the body's cells in phospholipid form.

Omega-3 fatty acids, in combination with diet and exercise, work by lowering the body's production of “bad”, low density lipoprotein (LDL) and triglycerides, and may raise high density lipoprotein (HDL) “good” cholesterol.

High levels of cholesterol and triglycerides can lead to coronary artery disease, heart disease, and stroke.
Supportive, but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.



WHAT ARE THE BENEFITS OF KRILL OIL?
In the realm of natural supplements, one name has been garnering increasing attention for its myriad health benefits: Krill Oil.

*Extracted from tiny crustaceans found in the icy waters of the Antarctic, Krill Oil has emerged as a powerhouse of essential nutrients, particularly renowned for its omega-3 fatty acid content.

But what exactly is Krill Oil, how does one incorporate it into their daily routine, and what wonders does it hold for our health?
Let's embark on a deep dive into the world of Krill Oil.



HEALTH BENEFITS OF KRILL OIL:
Krill oil's phospholipid-complex of omega-3 and choline provides support to the heart, brain, liver and eyes, with recent research showing benefits in skin and sports segments.



HOW TO USE KRILL OIL:
RECOMMENDED DOSE — (ORAL) ADULTS ONLY:
Take 1 to 2 softgel capsules three times per day.



WHY DO PEOPLE TAKE KRILL OIL?
Krill oil contains EPA and DHA, the same omega-3 fatty acids in fish oil, although usually in smaller amounts.
The effects of krill oil have not been researched as thoroughly as those of fish oil.

But a few preliminary studies suggest that krill oil could be superior in some ways.
Krill oil might be better absorbed in the body than fish oil.

One small study found that krill oil, like omega-3s in general, could improve rheumatoid arthritis and osteoarthritis symptoms such as pain, stiffness, and functional impairment.
It also lowered levels of C-reactive protein, a marker for inflammation in the body that's been linked with heart disease.

In addition, krill oil eased symptoms of premenstrual syndrome in another small study.
Because some studies indicate that the fatty acid DHA may benefit a developing child’s brain, krill oil is sometimes taken by pregnant women or given to children.



6 SCIENCE-BASED HEALTH BENEFITS OF KRILL OIL:
1. Excellent Source of Healthy Fats:
Both krill oil and fish oil contain the omega-3 fats EPA and DHA.

However, some evidence suggests that the fats found in krill oil may be easier for the body to use than those from fish oil, since most omega-3 fats in fish oil are stored in the form of triglycerides.

On the other hand, a large portion of the omega-3 fats in krill oil can be found in the form of molecules called phospholipids, which may be easier to absorb into the bloodstream.

A few studies found that krill oil was more effective than fish oil at raising omega-3 levels, and hypothesized that their differing forms of omega-3 fats might be why.

Another study carefully matched the amounts of EPA and DHA in krill oil and fish oil, and found that the oils were equally effective at raising levels of omega-3s in the blood.
More research is needed to determine whether krill oil is actually a more effective, bioavailable source of omega-3 fats than fish oil.


2. Can Help Fight Inflammation
Omega-3 fatty acids like those found in krill oil have been shown to have important anti-inflammatory functions in the body.
In fact, krill oil may be even more effective at fighting inflammation than other marine omega-3 sources because it appears to be easier for the body to use.

What’s more, krill oil contains a pink-orange pigment called astaxanthin, which has anti-inflammatory and antioxidant effects.
A few studies have begun to explore the specific effects of krill oil on inflammation.
One test-tube study found that it reduced the production of inflammation-causing molecules when harmful bacteria were introduced to human intestinal cells.


3. Might Reduce Arthritis and Joint Pain
Because krill oil seems to help reduce inflammation, it may also improve arthritis symptoms and joint pain, which often result from inflammation.
In fact, a study that found krill oil significantly reduced a marker of inflammation also found that krill oil reduced stiffness, functional impairment and pain in patients with rheumatoid or osteoarthritis.


4. Could Improve Blood Lipids and Heart Health
Omega-3 fats, and DHA and EPA specifically, are considered heart-healthy.

Research has shown that fish oil may improve blood lipid levels, and krill oil appears to be effective as well.
Studies have shown it may be particularly effective at lowering levels of triglycerides and other blood fats.
One study compared the effects of krill oil and purified omega-3s on cholesterol and triglyceride levels.

Only krill oil raised “good” high-density-lipoprotein (HDL) cholesterol.
It was also more effective at decreasing a marker of inflammation, even though the dosage was much lower.
On the other hand, the pure omega-3s were more effective at lowering triglycerides.

A recent review of seven studies concluded that krill oil is effective at lowering “bad” LDL cholesterol and triglycerides, and may increase “good” HDL cholesterol, too.

Another study compared krill oil to olive oil and found that krill oil significantly improved insulin resistance scores, as well as the function of the lining of the blood vessels.
More long-term studies are needed to investigate how krill oil affects the risk of heart disease.


5. Krill Oil may Help Manage PMS Symptoms
In general, consuming omega-3 fats may help decrease pain and inflammation.
Several studies have found that taking omega-3 or fish oil supplements can help decrease period pain and symptoms of premenstrual syndrome (PMS), in some cases enough to decrease the use of pain medication.

It appears that krill oil, which contains the same types of omega-3 fats, may be just as effective.
One study compared the effects of krill oil and fish oil in women diagnosed with PMS.

The study found that while both supplements resulted in statistically significant improvements in symptoms, women taking krill oil took significantly less pain medication than women taking fish oil.
This study suggests that krill oil may be at least as effective as other sources of omega-3 fats at improving PMS symptoms.


6. Krill Oil’s Easy to Add to Your Routine
Taking krill oil is a simple way to increase your EPA and DHA intake.
Krill Oil’s widely available and can be purchased online or at most pharmacies.
The capsules are typically smaller than those of fish oil supplements, and may be less likely to cause belching or a fishy aftertaste.

Krill oil is also typically considered to be a more sustainable choice than fish oil, because krill are so abundant and reproduce quickly.
Unlike fish oil, Krill Oil also contains astaxanthin.



KRILL OIL VS. FISH OIL:
While krill and fish oil both have DHA and EPA, it’s believed that those omega-3 fatty acids found in krill oil have a higher bioavailability — or rate of absorption in your body — than fish oil.

It might have something to do with the DHA and EPA being found as molecules called phospholipids in krill oil.
In fish oil, the DHA and EPA are stored in the form of triglycerides.
More research is needed to determine the exact reason krill oil might be absorbed more easily.


KRONOS 2056
KRONOS 2056 KRONOS 2056 is a versatile pigment with a warm tone recommended for conventional air-drying paints, silicate paints, plasters, silicone resin paints and impregnating baths for paper laminates. It confers good exterior durability. KRONOS 2056 is a versatile pigment with a warm tone recommended for plasticisers and various types of plastics. It confers good exterior durability. Kronos 2056 KRONOS 2056 is titanium dioxide. It is a rutile pigment produced by the sulphate process and surface treated with aluminium and silicon compounds. It disperses readily, provides good opacity and a warm tone, confers good exterior durability. KRONOS 2056 is suitable for use in conventional air drying paints, silicate paints and plasters, silicone resin paints. Product Type Titanium dioxide Chemical Composition Titanium dioxide CAS Number 13463-67-7 Product Description A versatile pigment with a warm tone Applications Conventional air drying paints Silicate paints and plasters Silicone resin paints Plasticisers Various types of plastics Impregnating baths for paper laminates Properties disperses readily provides good opacity and a warm tone confers good exterior durability on coatings and plastics is certified according to DIN EN 12878:2014-07 for the colouring of building materials based on cement and/or lime ABOUT KRONOS INC KRONOS is one of the world‘s leading manufacturers of titanium dioxide (TiO2) and has been operating as an international company for more than 90 years. The group owes its significant market position to the quality of its products, innovation, technical experience and reliable customer service around the world. Titanium dioxide pigments are used in paints and coatings, plastics, paper, building materials, cosmetics, pharmaceuticals, foods and many other commercial products. KRONOS 2056 is a versatile pigment with a warm tone recommended for conventional air-drying paints, silicate paints, plasters, silicone resin paints and impregnating baths for paper laminates. It confers good exterior durability and is certified for the colouring of building materials based on cement and/or lime according to DIN EN 12878 : 2014-07. KRONOS 2056 is a versatile pigment with a warm tone recommended for plasticisers and various types of plastics. It confers good exterior durability.
Ksantan Gum
Potassium Tripolyphosphate; pentapotassium triphosphate; potassium triphosphate; KTPP; triphosphoric acid, potassium salt ; potassium triphosphate; potassium tripolyphosphat cas no:13845-36-8
KTPP
Potassium Tripolyphosphate; Potassium Triphosphate; pentapotassium triphosphate; Triphosphoric acid potassium salt; CAS NO: 13845-36-8
KTPP (LIKIT/GRANÜL)-(POTASSIUM TRI POLY PHOSPHATE)
L TARTARIC ACID; 2,3-Dihydroxybutanedioic acid; L-(+)-Tartaric acid; Tartaric Acid; (+)-Tartaric acid; (R,R)-(+)-Tartaric acid; (R,R)-Tartaric acid; (2R,3R)-Tartaric acid; 2,3-dihydroxy-Butanedioic acid; L(+)-Tartaric acid; L-Tartaric acid; , 2,3-dihydroxy-Succinic acid; Threaric acid; 1,2-Dihydroxyethane- 1,2-dicarboxylic acid; (2R,3R)-(+)-Tartaric acid; (+)-(2R,3R)-Tartaric acid; d-Tartaric acid; Dextrotartaric acid; 3-hydroxy-Malic acid, ; Tartaric acid, (l); 2,3-Dihydrosuccinic acid; Kyselina 2,3-dihydroxybutandiova; Kyselina vinna; cas no: 87-69-4
L MALIC ACID (CAS 97-67-6)
L Malic Acid (Cas 97-67-6), is a naturally occurring carboxylic acid abundantly present in the human body.
L Malic Acid (Cas 97-67-6) is not only found in the human body but also occurs naturally in a wide range of foods.


CAS Number: 97-67-6
EC Number: 202-601-5
MDL number: MFCD00064213
Linear Formula: HO2CCH2CH(OH)CO2H
Molecular Formula: C4H6O5


L Malic Acid (Cas 97-67-6) is one of the popular food additives and ingredients in most countries.
L Malic Acid (Cas 97-67-6) is a metabolite found in or produced by Escherichia coli.
L Malic Acid (Cas 97-67-6) gives many fruits, particularly apples, their characteristic flavor.


L Malic Acid (Cas 97-67-6) is often referred to as “apple acid”.
The word malic is derived from the Latin mālum, for which Malus, the genus that contains all apple species, is also named.
L Malic Acid (Cas 97-67-6), also known as malate or L-apple acid, belongs to the class of organic compounds known as beta hydroxy acids and derivatives.


Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.
L Malic Acid (Cas 97-67-6) is an extremely weak basic (essentially neutral) compound (based on its pKa).
L Malic Acid (Cas 97-67-6) exists in all eukaryotes, ranging from yeast to humans.


L Malic Acid (Cas 97-67-6), is a naturally occurring carboxylic acid abundantly present in the human body.
L Malic Acid (Cas 97-67-6) is not only found in the human body but also occurs naturally in a wide range of foods.
Moreover, L Malic Acid (Cas 97-67-6) is produced during the fermentation of carbohydrates.


L Malic Acid (Cas 97-67-6) is soluble in acetone, dioxane, water, methanol and ethanol.
L Malic Acid (Cas 97-67-6) is insoluble in benzene
L Malic Acid (Cas 97-67-6) is incompatible with Bases, Oxidizing agents, Reducing agents, Alkali metals .


L Malic Acid (Cas 97-67-6) is the most typical acid occurring in fruits, it contributes to sour tastes.
L Malic Acid (Cas 97-67-6) is commonly used in beverages, confectionary and personal care products.
L Malic Acid (Cas 97-67-6) is a white crystalline powder.


L Malic Acid (Cas 97-67-6) is slightly sour taste.
L Malic Acid (Cas 97-67-6) is soluble in water.
L Malic Acid (Cas 97-67-6) is soluble in water(363g/L).


Keep L Malic Acid (Cas 97-67-6) container tightly closed.
Store L Malic Acid (Cas 97-67-6) away from oxidizing agents.
Store L Malic Acid (Cas 97-67-6) in cool, dry conditions in well sealed containers.


The most common is the L-isomer, L Malic Acid (Cas 97-67-6), present in the juice of immature hawthorn, apple and grape fruits.
L Malic Acid (Cas 97-67-6) can also be produced from fumaric acid through biological fermentation.
L Malic Acid (Cas 97-67-6) is an important intermediate product of the internal circulation of the human body and is easily absorbed by the human body.


L Malic Acid (Cas 97-67-6) is the naturally occurring isomer of malic acid, found mainly in sour and unripe fruits.
L Malic Acid (Cas 97-67-6), also known as malate or L-apple acid, belongs to the class of organic compounds known as beta hydroxy acids and derivatives.
Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.


L Malic Acid (Cas 97-67-6) exists in all eukaryotes, ranging from yeast to humans.
L Malic Acid (Cas 97-67-6) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, for intermediate use only.


L Malic Acid (Cas 97-67-6) is a dicarboxylic acid and organic compound made by all living organisms.
L Malic Acid (Cas 97-67-6) belongs to the class of organic compounds known as beta hydroxy acids and derivatives.
Beta hydroxy acids and derivatives are compounds containing a carboxylic acid substituted with a hydroxyl group on the C3 carbon atom.


L Malic Acid (Cas 97-67-6) is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste.
L Malic Acid (Cas 97-67-6) is nonpungent.
L Malic Acid (Cas 97-67-6) may be prepared by hydration of maleic acid; by fermentation from sugars.


L Malic Acid (Cas 97-67-6) is an organic acid that is commonly found in wine.
L Malic Acid (Cas 97-67-6) plays an important role in wine microbiological stability.
L Malic Acid (Cas 97-67-6) is an extremely weak basic (essentially neutral) compound (based on its pKa).


Malic Acid (Cas 97-67-6) is an organic compound, and is a dicarboxylic acid that is made by all living organisms, contributes to the pleasantly sour taste of fruits, and is used as a food additive.
Malic Acid (Cas 97-67-6) has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally. The salts and esters of malic acid are known as malates.


The malate anion is an intermediate in the citric acid cycle.
L Malic Acid (Cas 97-67-6) is the naturally occurring and more bioavailable form of Malic Aid.
Malic acid, also known as 2-hydroxysuccinic acid, has two stereoisomers due to an asymmetric carbon atom in the molecule.


In nature, it exists in three forms, namely D-malic acid, L-malic acid and its mixture DL-malic acid.
Malic Acid is white crystal or crystalline powder with strong hygroscopicity, easily soluble in water and ethanol, and has a special pleasant sour taste.
Analytical standard solution for use as a control sample or calibrator with analytical test kits that measure L Malic Acid (Cas 97-67-6).


Especially for use to generate calibration curves for auto-analyser or microplate assay formats with the following enzymatic tests kits: K-LMALAF, K-LMALQR.
L Malic Acid (Cas 97-67-6) is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.



USES and APPLICATIONS of L MALIC ACID (CAS 97-67-6):
L Malic Acid (Cas 97-67-6) is used as Selective α-amino protecting reagent for amino acid derivatives.
Versatile synthon for the preparation of chiral compounds including κ-opioid rece.
L Malic Acid (Cas 97-67-6) also acts as active ingredient in many sour or tart foods.


L Malic Acid (Cas 97-67-6) is used as synthesizing disincrustant and fluorescent whitening agent.
L Malic Acid (Cas 97-67-6) aids in the production of polyester and alcohol acid resins.
Beyond its biological significance, L Malic Acid (Cas 97-67-6) finds application in diverse industrial sectors.


L Malic Acid (Cas 97-67-6) contributes to the production of plastics, solvents, and detergents.
However, the precise mechanism of action of L Malic Acid (Cas 97-67-6) remains partially understood.
L Malic Acid (Cas 97-67-6) is hypothesized to be involved in ATP production and the transport of electrons within the electron transport chain.


Furthermore, L Malic Acid (Cas 97-67-6) is believed to partake in the metabolism of carbohydrates, fats, and proteins.
In its stable isotope-labeled form, L Malic Acid (Cas 97-67-6) is commonly used as an authentic standard for metabolite quantification.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.


L Malic Acid (Cas 97-67-6) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive.
L Malic Acid (Cas 97-67-6) is used for resolution of racemates for synthesis.


L Malic Acid (Cas 97-67-6) is an organic dicarboxylic acid that is present in various foods and is metabolized in humans through the Krebs (or citric acid) cycle.
Therefore, as a food additive and functional food with excellent performance, L Malic Acid (Cas 97-67-6) is widely used in food, cosmetics, medical and health care products and other fields.


The racemate can be prepared from fumaric acid or maleic acid under the action of a catalyst under high temperature and pressure conditions and water vapor.
L Malic Acid (Cas 97-67-6) is used to selectively protect the a-amino group of amino acids.
L Malic Acid (Cas 97-67-6) is the starting material for the preparation of chiral compounds.


L Malic Acid (Cas 97-67-6) may be used to prepare:diethyl (S)-malateethyl (R)-2-hydroxyl-4-phenylbutanoateethyl (S)-2-hydroxyl-4-phenylbutanoateD-homophenylalanine ethyl ester hydrochloridefuro[3,2-i]indolizines.
L Malic Acid (Cas 97-67-6) is a relevant component of the citric acid cycle that is found in animals, plants and microorganisms.


L Malic Acid (Cas 97-67-6) is one of the most important fruit acids found in nature and it is the acid present in highest concentrations in wine.
L Malic Acid (Cas 97-67-6) may be used in food production because it is a stronger acid than citric acid.
Microbial decomposition of L Malic Acid (Cas 97-67-6) leads to the formation of L-lactate; this can be a desirable reaction in the wine industry, where the level of L Malic Acid (Cas 97-67-6) is monitored, along with L-lactic acid, during malolactic fermentation.


L Malic Acid (Cas 97-67-6) may be used as a food preservative (E296) or flavour enhancing additive.
L Malic Acid (Cas 97-67-6) is responsible for the sour taste of most fruits and is utilized as a food additive.
Ungraded products supplied by Spectrum are indicative of a grade suitable for general industrial use or research purposes and typically are not suitable for human consumption or therapeutic use.


L Malic Acid (Cas 97-67-6) is used at industrial sites.
L Malic Acid (Cas 97-67-6) is used in the following products: laboratory chemicals and pharmaceuticals.
L Malic Acid (Cas 97-67-6) is used for the manufacture of: chemicals.


Release to the environment of L Malic Acid (Cas 97-67-6) can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates).
L Malic Acid (Cas 97-67-6) is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives.


Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants.
Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece.


L Malic Acid (Cas 97-67-6) is used intermediate in chemical synthesis.
L Malic Acid (Cas 97-67-6) is used chelating and buffering agent.
L Malic Acid (Cas 97-67-6) is used flavoring agent, flavor enhancer and acidulant in foods.


-Food Industry uses of L Malic Acid (Cas 97-67-6):
L Malic Acid (Cas 97-67-6) is an important component of natural fruit juice.
Compared with citric acid, it has higher acidity (20% stronger acidity than citric acid), but soft taste (higher buffer index).

L Malic Acid (Cas 97-67-6) has a special fragrance, does not damage the mouth and teeth, is beneficial to the absorption of amino acids in metabolism, and does not accumulate fat.
L Malic Acid (Cas 97-67-6) is a new generation of food sour agent.
L Malic Acid (Cas 97-67-6) is praised as "the most ideal food sour agent" by the biological and nutritional circles.



ENZYMATIC METHOD FOR THE DETERMINATION OF L MALIC ACID (CAS 97-67-6):
Based on the spectrophotometric measurement of NADH formed through the combined action of L-malate dehydrogenase (L-LDH) and aspartate aminotransferase (AST).
This rapid and simple stereo-specific enzymatic method is used for the determination of L Malic Acid (Cas 97-67-6) (L-malate) in foodstuffs such as wine, beer, bread, fruit and vegetable products, fruit juice, as well as in cosmetics, pharmaceuticals, and biological samples.



ALTERNATIVE PARENTS OF L MALIC ACID (CAS 97-67-6):
*Short-chain hydroxy acids and derivatives
*Fatty acids and conjugates
*Dicarboxylic acids and derivatives
*Alpha hydroxy acids and derivatives
*Secondary alcohols
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF L MALIC ACID (CAS 97-67-6):
*Short-chain hydroxy acid
*Beta-hydroxy acid
*Fatty acid
*Dicarboxylic acid or derivatives
*Alpha-hydroxy acid
*Secondary alcohol
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxygen compound
*Organic oxide
*Hydrocarbon derivative
*Organooxygen compound
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound



CHEMICAL PROPERTIES OF L MALIC ACID (CAS 97-67-6):
L Malic Acid (Cas 97-67-6) is nearly odorless (sometimes a faint, acrid odor).
L Malic Acid (Cas 97-67-6) has a tart, acidic, nonpungent taste.
L Malic Acid (Cas 97-67-6) is a clear colourless solution
L Malic Acid (Cas 97-67-6) occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
L Malic Acid (Cas 97-67-6) is an optically active form of malic acid having (S)-configuration.



PREPARATION OF L MALIC ACID (CAS 97-67-6):
L Malic Acid (Cas 97-67-6) can be prepared by hydration of maleic acid; by fermentation from sugar.



BIOCHEM/PHYSIOL ACTIONS OF L MALIC ACID (CAS 97-67-6):
L Malic Acid (Cas 97-67-6) is a part of cellular metabolism.
L Malic Acid (Cas 97-67-6)'s application is recognized in pharmaceutics.
L Malic Acid (Cas 97-67-6) is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia.

L Malic Acid (Cas 97-67-6) is used as a part of amino acid infusion.
L Malic Acid (Cas 97-67-6) also serves as a nanomedicine in the treatment of brain neurological disorders.
A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.



PURIFICATION METHOD OF L MALIC ACID (CAS 97-67-6):
Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o.
Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point.



SUPPORTS HEALTH & WELLNESS OF L MALIC ACID (CAS 97-67-6)::
L Malic Acid (Cas 97-67-6) supports energy production, supports an active lifestyle, and aids in absorption of iron in the body.
Alpha-hydroxy acids are also known to support healthy skin and oral health.



CONVENIENT RESEALABLE POUCH OF L MALIC ACID (CAS 97-67-6)::
Prescribed for Life L Malic Acid (Cas 97-67-6) Powder comes in a durable, resealable pouch.
It’s easy to store and keeps your L Malic Acid (Cas 97-67-6) Powder fresh for maximum long shelf life.



PHYSICAL and CHEMICAL PROPERTIES of L MALIC ACID (CAS 97-67-6):
Molecular Weight: 134.09 g/mol
XLogP3: -1.3
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 5
Rotatable Bond Count: 3
Exact Mass: 134.02152329 g/mol
Monoisotopic Mass: 134.02152329 g/mol
Topological Polar Surface Area: 94.8Ų
Heavy Atom Count: 9
Formal Charge: 0
Complexity: 129
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS Number: 97-67-6
Molecular Weight: 134.09
Beilstein: 1723541

EC Number: 202-601-5
MDL number: MFCD00064213
CAS Number: 97-67-6
Purity: ≥98%
Molecular Weight: 134.1
Molecular Formula: C4H6O5
Physical state: powder
Color: white
Odor: No data available
Melting point/freezing point:
Melting point/range: 101 - 103 °C - lit.
Initial boiling point and boiling range: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: Not applicable
Autoignition temperature: No data available
Decomposition temperature: No data available
pH: No data available
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Water solubility: No data available
Partition coefficient: n-octanol/water: No data available

Vapor pressure: No data available
Density: 1,595 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
CAS number: 97-67-6
EC number: 202-601-5
Hill Formula: C₄H₆O₅
Chemical formula: HOOCCH(OH)CH₂COOH
Molar Mass: 134.08 g/mol
HS Code: 2918 19 98
Boiling point: 140 °C (decomposition)
Density: 1.60 g/cm3 (20 °C)
Melting Point: 98 - 103 °C
pH value: 2.2 (10 g/l, H₂O, 20 °C)
Bulk density: 600 kg/m3
Solubility: 160 g/l
CAS NUMBER: 97-67-6
MOLECULAR FORMULA:C4H6O5
MOLECULAR WEIGHT: 134.1

BEILSTEIN REGISTRY NUMBER: 1723541
EC NUMBER: 202-601-5
MDL NUMBER: MFCD00064213
CAS #: 97-67-6
EC Number: 202-601-5
Grade: Cell Culture Grade
Hazard Statements: H315-H319-H335
Melting Point: 101-103 °C(lit.)
Molecular Formula: C4H6O5
Molecular Weight: 134.1
CAS: 97-67-6
Molecular Formula: C4H6O5
Molecular Weight (g/mol): 134.087
MDL Number: MFCD00064213
InChI Key: BJEPYKJPYRNKOW-REOHCLBHSA-N
PubChem CID: 222656
ChEBI: CHEBI:30797
IUPAC Name: (2S)-2-hydroxybutanedioic acid
SMILES: C(C(C(=O)O)O)C(=O)O
Melting Point: 100°C to 106°C
Color: White
Density: 1.6
Flash Point: 220°C (428°F)

Beilstein: 1723541
Merck Index: 14,5707
Solubility Information: Soluble in water(363g/L).
Optical Rotation: −26° (c=5.5 in pyridine)
Formula Weight: 134.09
Percent Purity: 99%
Physical Form: Crystalline Powder
Chemical Name or Material: L-(-)-Malic acid
Density: 1.6±0.1 g/cm3
Boiling Point: 306.4±27.0 °C at 760 mmHg
Melting Point: 101-103 °C(lit.)
Molecular Formula: C4H6O5
Molecular Weight: 134.087
Flash Point: 153.4±20.2 °C
Exact Mass: 134.021530
PSA: 94.83000
LogP: -1.26
Vapour Pressure: 0.0±1.5 mmHg at 25°C
Index of Refraction: 1.529
Water Solubility: soluble
Molecular Formula / Molecular Weight: C4H6O5 = 134.09
Physical State (20 deg.C): Solid
Store Under Inert Gas: Store under inert gas

Condition to Avoid: Air Sensitive
CAS RN: 97-67-6
Reaxys Registry Number: 1723541
PubChem Substance ID: 87572140
SDBS (AIST Spectral DB): 1069
Merck Index (14): 5707
MDL Number: MFCD00064213
CAS number: 97-67-6
Weight Average: 134.0874
Monoisotopic: 134.021523302
InChI Key: BJEPYKJPYRNKOW-REOHCLBHSA-N
InChI: InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
IUPAC Name: (2S)-2-hydroxybutanedioic acid
Traditional IUPAC Name: (-)-malic acid
Chemical Formula: C4H6O5
SMILES: O[C@@H](CC(O)=O)C(O)=O
Water Solubility: 218 g/L
logP: -0.87
logP: -1.1
logS: 0.21
pKa (Strongest Acidic): 3.2
pKa (Strongest Basic): -3.9
Physiological Charge: -2
Hydrogen Acceptor Count: 5
Hydrogen Donor Count: 3
Polar Surface Area: 94.83 Ų

Rotatable Bond Count: 3
Refractivity: 24.88 m³·mol⁻¹
Polarizability: 10.93 ų
Number of Rings: 0
Bioavailability: Yes
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: No
MDDR-like Rule: No
Chemical Formula: C4H6O5
IUPAC name: (2S)-2-hydroxybutanedioic acid
InChI Identifier: InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
InChI Key: BJEPYKJPYRNKOW-REOHCLBHSA-N
Isomeric SMILES: O[C@@H](CC(O)=O)C(O)=O
Average Molecular Weight: 134.0874
Monoisotopic Molecular Weight: 134.021523302
Melting point : 101-103 °C (lit.)
alpha: -2 º (c=8.5, H2O)
Boiling point : 167.16°C (rough estimate)
density: 1.60
vapor pressure: 0 Pa at 25℃
FEMA: 2655 | L-MALIC ACID
refractive index: -6.5 ° (C=10, Acetone)

Fp : 220 °C
storage temp.: Store below +30°C.
solubility: H2O: 0.5 M at 20 °C, clear, colorless
form: Powder
color: White
Specific Gravity: 1.595 (20/4℃)
Odor: odorless
PH: 2.2 (10g/l, H2O, 20℃)
pka: (1) 3.46, (2) 5.10(at 25℃)
Odor Type: odorless
optical activity: [α]20/D 30±2°, c = 5.5% in pyridine
Water Solubility: soluble
Merck: 14,5707
JECFA Number: 619
BRN: 1723541
InChIKey: BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP: -1.68
CAS DataBase Reference: 97-67-6(CAS DataBase Reference)
NIST Chemistry Reference: Butanedioic acid, hydroxy-, (s)-(97-67-6)
EPA Substance Registry System: Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6)



FIRST AID MEASURES of L MALIC ACID (CAS 97-67-6):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of L MALIC ACID (CAS 97-67-6):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of L MALIC ACID (CAS 97-67-6):
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of L MALIC ACID (CAS 97-67-6):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of L MALIC ACID (CAS 97-67-6):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of L MALIC ACID (CAS 97-67-6):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
no information available
-Incompatible materials:
No data available



SYNONYMS:
97-67-6
L-Malic acid
L-(-)-Malic acid
(S)-2-hydroxysuccinic acid
(2S)-2-Hydroxybutanedioic acid
(S)-Malic acid
L(-)-Malic acid
(-)-Malic acid
L-Apple acid
Apple acid
(-)-Hydroxysuccinic acid
L-malate
S-(-)-Malic acid
L-Hydroxybutanedioic acid
S-2-Hydroxybutanedioic acid
Butanedioic acid, hydroxy-, (2S)-
Malic acid, L-
L-2-Hydroxybutanedioic acid
(S)-(-)-Hydroxysuccinic acid
CHEBI:30797
(-)-L-Malic acid
(S)-malate
Malic acid L-(-)-form
Hydroxysuccinnic acid (-)
L-Hydroxysuccinic acid
J3TZF807X5
CHEMBL1234046
NSC9232
NSC-9232
MFCD00064213
NSC 9232
Butanedioic acid, 2-hydroxy-, (2S)-
(S)-Hydroxybutanedioic acid
MALATE ION
(-)-(S)-Malic acid
Hydroxybutanedioic acid, (-)-
UNII-J3TZF807X5
malic-acid
Hydroxybutanedioic acid, (S)-
2yfa
4elc
4ipi
4ipj
L-Maleic Acid
L-Hydroxysuccinate
2-Hydroxybutanedioic acid, (S)-
(S)-(-)-2-Hydroxysuccinic acid
(2s)-malic acid
EINECS 202-601-5
L-Hydroxybutanedioate
nchembio867-comp7
L-(-) malic acid
(-)-Hydroxysuccinate
L-(-)-Apple Acid
S-(-)-Malate
(S)-Hydroxybutanedioate
S-2-Hydroxybutanedioate
(-)-(S)-Malate
(S)-(-)-malic acid
(S)-hydroxy-Butanedioate
(S)-Hydroxysuccinic acid
L(-)MALIC ACID
(S)-2-hydroxysuccinicacid
bmse000238
MALIC ACID [HSDB]
MALIC ACID, (L)
(S)-(-)-Hydroxysuccinate
L-MALIC ACID [FHFI]
(S)-hydroxy-Butanedioic acid
SCHEMBL256122
L-MALIC ACID [WHO-DD]
MALIC ACID, L- [II]
(-)-(s)-hydroxybutanedioic acid
DTXSID30273987
BJEPYKJPYRNKOW-REOHCLBHSA-N
(2S)-(-)-hydroxybutanedioic acid
AMY40197
HY-Y1069
BDBM50510127
s6292
AKOS006346693
CS-W020132
MALIC ACID L-(-)-FORM [MI]
L-(-)-Malic acid, BioXtra, >=95%
AS-18628
L-(-)-Malic acid, >=95% (titration)
(S)-E 296
(-)-1-Hydroxy-1,2-ethanedicarboxylic acid
M0022
EN300-93424
C00149
L-(-)-Malic acid, purum, >=99.0% (T)
L-(-)-Malic acid, ReagentPlus(R), >=99%
M-0850
35F9ECA9-BBE6-463D-BF3F-275FACC5D14E
L-(-)-Malic acid, SAJ special grade, >=99.0%
L-(-)-Malic acid, Vetec(TM) reagent grade, 97%
Q27104150
Z1201618618
(S)-(-)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid
L-(-)-Malic acid, 97%, optical purity ee: 99% (GLC)
L-(-)-Malic acid, certified reference material, TraceCERT(R)
L-(-)-Malic acid, BioReagent, suitable for cell culture, suitable for insect cell culture
26999-59-7
(S)-(−)-2-Hydroxysuccinic acid
L-Hydroxybutanedioic acid
(2S)-2-Hydroxybutanedioic acid
l-Malic acid
Apple acid
(-)-Malic acid
L-Hydroxysuccinic acid
(S)-(-)-2-Hydroxysuccinic acid
L-Hydroxybutanedioic acid
l-malic acid, l---malic acid
s-2-hydroxysuccinic acid
2s-2-hydroxybutanedioic acid
l--malic acid, apple acid
--malic acid
l-apple acid
s-malic acid
s-2-hydroxybutanedioic acid
(S)-Hydroxybutanedioic Acid
L-Hydroxysuccinic Acid
(-)-(S)-Malate
(-)-(S)-Malic acid
(-)-Hydroxysuccinate
(-)-Hydroxysuccinic acid
(-)-L-Malic acid
(-)-Malic acid
(2S)-2-Hydroxybutanedioate
(2S)-2-Hydroxybutanedioic acid
(S)-(-)-Hydroxysuccinate
(S)-(-)-Hydroxysuccinic acid
(S)-hydroxy-Butanedioate
(S)-hydroxy-Butanedioic acid
(S)-Hydroxybutanedioate
(S)-Hydroxybutanedioic acid
(s)-malate
Apple acid
Butanedioic acid, hydroxy-, (S)-
L-(-)-Malic acid
l-2-hydroxybutanedioic acid
l-apple acid
L-Hydroxybutanedioate
L-Hydroxybutanedioic acid
L-Hydroxysuccinate
L-Hydroxysuccinic acid
L-Malate
L-malic acid
malate
Malic acid
MLT
S-(-)-Malate
S-(-)-Malic acid
S-2-Hydroxybutanedioate
S-2-Hydroxybutanedioic acid
(-)-L-Malate
L-2-Hydroxybutanedioate
(S)-Malic acid
(2S)-2-Hydroxysuccinic acid
(2S)-Malic acid
(S)-2-Hydroxysuccinic acid
2-Hydroxybutanedioic acid
2-Hydroxyethane-1,2-dicarboxylic acid
2-Hydroxysuccinic acid
Deoxytetraric acid
Hydroxybutanedioic acid
Hydroxysuccinic acid
Monohydroxybutanedioic acid
alpha-Hydroxysuccinic acid
α-Hydroxysuccinic acid
(+-)-1-Hydroxy-1,2-ethanedicarboxylic acid
(+-)-hydroxysuccinic acid
(+-)-malic acid biospider
(+/-)-2-Hydroxysuccinic acid
(-)-(S)-Malate
(-)-(S)-Malic acid
(-)-Hydroxysuccinate
(-)-Hydroxysuccinic acid
(-)-L-Malate Generator
(-)-L-Malic acid
L-(-)-Malic acid, CP
Butanedioic acid, 2-hydroxy-, (2S)-
pinguosuan
Butanedioicacid,hydroxy-,(S)-
hydroxy-,(S)-Butanedioicacid
l-(ii)-malicacid
L-Gydroxybutanedioicacid
L-Mailcacid


L TARTARIC ACID
L Tartaric Acid

CAS No: 144814-09-5, 87-69-4, 133-37-9
EC No: 201-766-0
Molecular Formula: C4H6O6
Molecular Weight: 150.086 g/mol



APPLICATIONS


L Tartaric Acid is used to give a sour taste.
Furthermore, L Tartaric Acid is a good antioxidant.
L Tartaric Acid is the most common area for making soda.

L Tartaric Acid can be used to polish, polish and protect metals.
Oven products are used by releasing carbon dioxide.

Gelatinous desserts are preferred as thickeners in products such as L Tartaric Acid, meringue, lokum and cream whipped cream.
L Tartaric Acid obtained from grapes is highly preferred in useful pasta production.
For embossing of macaroni, L Tartaric Acid maembossed gravy instead.

The production of L Tartaric Acid wine, which has a low density, a piquant and strong taste, is preferred for fermentation of wine
L Tartaric Acid is used for making marmalade and jams.

There are several methods for the production of L Tartaric Acid.
A few of them are as follows:

Besides, L Tartaric Acid can form from the chemical reaction between Calcium Tartrate and an aqueous sulfuric acid solution.
CaC4H4O6 + H2SO4 & gt; H2C4H4O6 + CaSO4

L Tartaric Acid produced by this reaction is the only additive chemistry used to regulate acidity in the production of wines.
The major chemical substances and components used in the production of L Tartaric Acid are water, sulfuric acid and calcium.

Moreover, L Tartaric Acid is used to produce sodium carbonate, as a result of its interaction with sodium bicarbonate, by oral administration this effect of L Tartaric Acid, carbon dioxide prolongs the mast.
L Tartaric Acid is used as an antioxidant to give a sour taste to many food products.

In addition, L Tartaric Acid is used to add the embossing qualities in the food additives that are added to the bakery products.
L Tartaric Acid isused as a preservative additive in foods.
At the same time, L Tartaric Acid gives flavor.

L Tartaric Acid is generally used in the production of carbonated beverages, fruit candies and products in effervescent tablets.
At the same time, L Tartaric Acid is used to polish and clean metals and deeply tannate.
Therefore, we can think that L Tartaric Acid can also be used in sun cream production.

L Tartaric Acid is used in the manufacture of blue inks.
In addition, L Tartaric Acid is used as a component that reacts with Silver Nitrateto give the mirror silver color.
L Tartaric Acid is used for fabric dyeing with ester derivatives.
Additionally, L Tartaric Acid will be useful for performing the process required here.

L Tartaric Acid is used in wine production to preserve the color, chemical stability and taste of finished wine products.
One of the reasons for the use of L Tartaric Acid in wine production is to reduce the pH of the medium and prevent unwanted bacterial growth.
L Tartaric Acid is a useful chemical for the production of chiral molecules in organic chemistry.

When the L Tartaric Acid cream is added to the water, the copper mine forms a very well cleaned suspension.
L Tartaric Acid is used as an aroma in food and beverages.

L Tartaric Acid may be used in the synthesis of (R,R)-1,2-diammoniumcyclohexane mono-(+)-tartrate, an intermediate to prepare an enantioselective epoxidation catalyst.
More to that, L Tartaric Acid may also be used as a starting material in the multi-step synthesis of 1,4-di-O-benzyl-L-threitol.

L Tartaric Acid can be used a chiral resolving agent for the resolution of 2,2′-bispyrrolidine.
Further to that, L Tartaric Acid is chiral building block for natural products.
L Tartaric Acid also forms a Diels-Alder catalyst with TiCl2(O-i-Pr)2.


Industrial uses of L Tartaric Acid:

Food Industry:

Acidifiers and natural preservatives for jams, ice creams, jams, juices, jams and beverages
Foamer for carbonated water
In bread making sector like emulsifier and preservative; in preparing candies and sweets


Wine Industry:

L Tartaric Acid is used as an acidifier.
Furthermore, L Tartaric Acid provides an increase in acidity and a decrease in pH content, which is necessary to prepare more balanced wines interms of taste and used in wines.


Pharmaceutical Industry:

Melt in water is used as an additive for the preparation of tablets.


Building Sector:

L Tartaric Acid delays the operation and facilitates the processing of these materials. (Also used in Cement and Plaster)


Cosmetic Industry:

L Tartaric Acid is used as a basic component in many natural body creams.


Chemical Sector:

Galvanic bathrooms


Electronics industry:

Color stabilizer like the textile industry
Industrial grease as anti-oxidant


Uses of L Tartaric Acid:

Multi-component crafting kits where individual products are not designated
Products related to pottery making which can not be assigned to a more refined category
Products specifically used in a laboratory setting, e.g. laboratory diagnostics or consumables, solvents and reagents used in experiments or laboratory tests, etc. Includes supplies for medical testing. Note that pure chemicals will be included in the 'Raw materials' category.
Medical and dental supplies and equipment, e.g. medical equipment used in a hospital or doctor's office setting, at home (e.g. wheelchairs, colostomy bag). Includes clothing and personal protective equipment used in medical settings (e.g. scrubs, face masks, gowns, gloves); excludes medical testing supplies.
Fragrances, colognes, and perfumes
General hair styling or hair care products which do not fit into a more refined category
Lip products primarily for protection
Colored lip products, excluding glosses
Miscellaneous aquarium products for the maintenance of aquatic pets
rinse aid
surfactant
ph regulating agent
processing aids and additives


L Tartaric Acid is found throughout nature and classified as a fruit acid.
Moreover, L Tartaric Acid is used in soft drinks and foods, as an acidulant, complexing agent, pharmaceutic aid (buffering agent), in photography, tanning, ceramics, and to make tartrates.

Diethyl and dibutyl ester derivatives are commercially significant for use in lacquers and in textile printing.
L Tartaric Acid is used as an intermediate, in construction and ceramics applications, in cleaning products, cosmetics/personal care products, and metal surface treatments (including galvanic and electroplating products).

Besides, L Tartaric Acid is used as a flavoring agent, anticaking agent, drying agent, firming agent, humectant, leavening agent, and pH control agent for foods.
L Tartaric Acid is permitted for use as an inert ingredient in non-food pesticide products.



DESCRIPTION


L Tartaric Acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes, but also in bananas, tamarinds, and citrus.
Its salt, potassium bitartrate, commonly known as cream of tartar, develops naturally in the process of fermentation.
L Tartaric Acid is commonly mixed with sodium bicarbonate and is sold as baking powder used as a leavening agent in food preparation.

L Tartaric Acid itself is added to foods as an antioxidant E334 and to impart its distinctive sour taste.
Naturally occurring L Tartaric Acid is a useful raw material in organic chemical synthesis.
L Tartaric Acid is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

L Tartaric Acid, a crystalline acid, is commonly found in plants and fruits.
In addition, L Tartaric Acid is white in color and crystalline.
L Tartaric Acid is a succinic acid is a dihydroxyl derivative.

Additionally, L Tartaric Acid has polarizing power.
L Tartaric Acid is an acidic potassium salt, which is derived from fermented grape juice.

L Tartaric Acid is designated as natural tartaric acid.
Natural Tartaric is a product of nature.
L Tartaric acid, i.e., natural tartaric acid, is obtained as by-products of wine making after obtaining alcoholic products.

More to that, L Tartaric acid should not be mixed with synthetic tartaric acid, starting from synthetic maleic acid.
L Tartaric Acid crystallizer is applied in two stages.

L Tartaric Acid has 2 purity.
The raw crystal of L (+) Tartaric Acid, i.acid, is re-dissolved and subsequently converted back into crystalline structure.
L Tartaric acid produced in this manner, i.eacid, abolishes the process residues in the application phase.

Further to that, L Tartaric Acid acid has a white crystalline residue.
Sometimes the crystalline powder can also be in structure.
The tartaric acid melting point is 206 [deg.] C.

L Tartaric Acid is a chemical that works by inhibiting the production of malic acid.
In this process, a person is exposed to tartaricdoses, resulting in Toxic accumulation in the muscles.
The high dose of L Tartaric Acid can cause paralysis and death as a result.

L Tartaric Acid prices continue to drive up prices due to increased wine consumption.
The price of L Tartaric Acid also increases the demand for L Tartaric Acid by increasing the popularity of packaged food products.
Therefore, the price of L Tartaric Acid is also increasing.
The price of L Tartaric Acid is increasing due to its use as an emulsifier in bread production.

L Tartaric Acid (E 334); crystalline, colorless organic acid commonly found in plants.
This acid which is used in various industrial branches, especially in the food industry, is obtained as a by-product of potassium during the fermentation of the wine.
L Tartaric Acid is first separated from this mixture by Carl Wilhem Scheele.

The wastes generated in the wine production are neutralized with potassium hydroxide.
L Tartaric Acid is formed by processing calcium tartar with sulfuric acid in the flour.

L Tartaric Acid is used in soda, gelatinous desserts, cleaning and polishing of metals and wool painting.
Antimony potassium tartar is also used asan insecticide and mordant.
L Tartaric Acid accounts for 1.6-2.8% of total acid in grape fruits.



PROPERTIES



Melting point: 170-172 °C(lit.)
alpha: 12 º (c=20, H2O)
Boiling point: 191.59°C (rough estimate)
Density: 1.76
vapor density: 5.18 (vs air)
vapor pressure: refractive index: 12.5 ° (C=5, H2O)
Flash point: 210 °C
storage temp.: Store at +5°C to +30°C.
solubility:
H2O: soluble1M at 20°C, clear, colorless
form : Solid
pka: 2.98, 4.34(at 25℃)
color: White or colorless
PH: 3.18(1 mM solution);2.55(10 mM solution);2.01(100 mM solution);
Optical activity: [α]20/D +13.5±0.5°, c = 10% in H2O
Water Solubility: 1390 g/L (20 ºC)
Merck: 14,9070
JECFA Number: 621
BRN: 1725147
Stability: Stable. Incompatible with oxidizing agents, bases, reducing agents. Combustible.



FIRST AID


First-aid measures general:

Never give anything by mouth to an unconscious person.
If you feel unwell, seek medical advice (show the label where possible).


First-aid measures after inhalation:

Allow victim to breathe fresh air.
Allow the victim to rest.


First-aid measures after skin contact:

Remove affected clothing and wash all exposed skin area with mild soap and water, followed by warm water rinse.


First-aid measures after eye contact:

Rinse cautiously with water for several minutes.
Remove contact lenses, if present and easy to do.
Continue rinsing.
Immediately call a poison center or doctor/physician.


First-aid measures after ingestion:

Rinse mouth.
Do NOT induce vomiting.
Obtain emergency medical attention.



HANDLING AND STORAGE


L Tartaric Acid should not be stored in areas directly exposed to sunlight.
Furthermore, L Tartaric Acid appears to be converted to glyoxylic acidin areas exposed to sunlight.

L Tartaric Acid will react with each other to produce hydrogen peroxide and glyoxylic acid formic aunder these conditions.
Therefore, L Tartaric Acid is not stable.
Moreover, L Tartaric Acid is packed in paper bags of 25 kg, 500 kg and 1500 kg.


Precautions for safe handling:

Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work.
Provide good ventilation in process area to prevent formation of vapor.


Hygiene measures:

Wash exposed skin thoroughly after handling.


Conditions for safe storage, including any incompatibilities:

Storage conditions:

Keep container closed when not in use.


Incompatible products:

Strong bases.
Strong oxidizers.


Incompatible materials:

Sources of ignition.
Direct sunlight.



SYNONYMS


87-69-4;L-tartaric acid
L-(+)-Tartaric acid
L(+)-Tartaric acid
(2R,3R)-2,3-dihydroxysuccinic acid
tartaric acid
(+)-L-Tartaric acid
(2Rdihydroxybutanedioic acid
(R,R)-Tartaric acid
Dextrotartaric acid
L-threaric acid
(+)-(R,R)-Tartaric acid
(+)-Tartaric acid
(2R,3R)-(acid;Tartaric acid (VAN)
Threaric acid
Kyselina vinna [Czech]
Acidum tartaricum
Tartaric acid [USAN:JAN]
Tartaric acid, L-
Succidihydroxy
UNII-W4888I119H
d-alpha,beta-Dihydroxysuccinic acid
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-
EINECS 201-766-0
Ntartaric acid
Kyselina 2,3-dihydroxybutandiova [Czech]
(2R,3R)-rel-2,3-Dihydroxysuccinic acid
AI3-06298
(+)-L-Tartaric acid
(+)-Tartaric acid
87-69-4
L-(+)-Tartaric acid
L-Tartaric acid
L(+)-Tartaric acid
tartaric acid
(2R,3R)-2,3-dihydroxysuccinic acid
(2R,3R)-2,3-dihydroxybutanedioic acid
(R,R)-Tartaric acid
Threaric acid
L-threaric acid
Dextrotartaric acid
DL-Tartaric acid
Natural tartaric acid
(2R,3R)-(+)-Tartaric acid
(+)-(R,R)-Tartaric acid
Tartaric acid, L-
Rechtsweinsaeure
(2R,3R)-Tartaric acid
(2R,3R)-rel-2,3-Dihydroxysuccinic acid
tartrate
(R,R)-(+)-Tartaric acid
FEMA No. 3044
133-37-9
Lamb protein (fungal)
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-
(R,R)-tartrate
Tartaric acid (VAN)
Kyselina vinna [Czech]
INS NO.334
Uvic acid
CHEBI:15671
(+)-(2R,3R)-Tartaric acid
INS-334
Tartaric acid [USAN:JAN]
Weinsaeure
MFCD00064207
NSC-62778
L-tartarate
4J4Z8788N8
W4888I119H
138508-61-9
Butanedioic acid, 2,3-dihydroxy-, (2R,3R)-rel-
1,2-Dihydroxyethane-1,2-dicarboxylic acid
Resolvable tartaric acid
d-alpha,beta-Dihydroxysuccinic acid
E 334
E-334
L-(+)-tartrate
144814-09-5
Kyselina 2,3-dihydroxybutandiova [Czech]
AI3-06298
(1R,2R)-1,2-Dihydroxyethane-1,2-dicarboxylic acid
2, 3-Dihydroxybutanedioic Acid
Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, homopolymer
Kyselina vinna
Tartaric acid D,L
Butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-
Tartarate
132517-61-4
(+/-)-Tartaric Acid
Succinic acid, 2,3-dihydroxy
L(+) tartaric acid
L-2,3-Dihydroxybutanedioic acid
(2RS,3RS)-Tartaric acid
EINECS 201-766-0
NSC 62778
Weinsteinsaeure
Weinsaure
tartaric-acid
L-Threaric aci
UNII-W4888I119H
Kyselina 2,3-dihydroxybutandiova
4ebt
NSC 148314
NSC-148314
(r,r)-tartarate
(2R,3R)-2,3-Dihydroxybernsteinsaeure
(+)-tartarate
(+)-Weinsaeure
l(+)tartaric acid
Tartaric acid; L-(+)-Tartaric acid
Tartaric acid (TN)
(+-)-Tartaric acid
Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-
L-(+) tartaric acid
(2R,3R)-Tartarate
1d5r
DL TARTARIC ACID
TARTARICUM ACIDUM
2,3-dihydroxy-succinate
TARTARIC ACID,DL-
DSSTox_CID_3632
EC 201-766-0
SCHEMBL5762
TARTARIC ACID [II]
TARTARIC ACID, DL-
DSSTox_RID_77120
Tartaric acid (JP17/NF)
TARTARIC ACID [FCC]
TARTARIC ACID [JAN]
d-a,b-Dihydroxysuccinic acid
DSSTox_GSID_23632
TARTARIC ACID [INCI]
MLS001336057
L-TARTARIC ACID [MI]
TARTARIC ACID [VANDF]
DL-TARTARIC ACID [MI]
TARTARIC ACID [MART.]
CCRIS 8978
L-(+)-Tartaric acid, ACS
TARTARIC ACID [USP-RS]
TARTARIC ACID [WHO-DD]
CHEMBL1236315
DTXSID8023632
L-(+)-Tartaric acid, BioXtra
TARTARICUM ACIDUM [HPUS]
UNII-4J4Z8788N8
(2R,3R)-2,3-tartaric acid
TARTARIC ACID (L(+)-)
HMS2270G22
Pharmakon1600-01300044
TARTARIC ACID, DL- [II]
ZINC895301
TARTARIC ACID, (+/-)-
TARTARIC ACID,DL- [VANDF]
HY-Y0293
STR02377
TARTARIC ACID [ORANGE BOOK]
BAROS COMPONENT TARTARIC ACID
EINECS 205-105-7
Tox21_300155
(2R,3R)-2,3-dihydroxysuccinicacid
NSC759609
s6233
TARTARIC ACID [EP MONOGRAPH]
L-2,3-DIHYDROXYSUCCINIC ACID
AKOS016843282
L-(+)-Tartaric acid, >=99.5%
CS-W020107
DB09459
NSC-759609
(2R,3R)-2,3-dihydroxy-succinic acid
Butanedioic acid, 2,3-dihydroxy-; Butanedioic acid, 2,3-dihydroxy-, (R-(R*,R*))-
CAS-87-69-4
L-(+)-Tartaric acid, AR, >=99%
TARTARIC ACID COMPONENT OF BAROS
NCGC00247911-01
NCGC00254043-01
BP-31012
SMR000112492
SBI-0207063.P001
T0025
EN300-72271
C00898
D00103
D70248
L-(+)-Tartaric acid, >=99.7%, FCC, FG
L-(+)-Tartaric acid, ACS reagent, >=99.5%
L-(+)-Tartaric acid, BioUltra, >=99.5% (T)
J-500964
J-520420
L-(+)-Tartaric acid, ReagentPlus(R), >=99.5%
L-(+)-Tartaric acid, SAJ first grade, >=99.5%
L-(+)-Tartaric acid, tested according to Ph.Eur.
REL-(2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID
Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-(+-)-
L-(+)-Tartaric acid, JIS special grade, >=99.5%
L-(+)-Tartaric acid, natural, >=99.7%, FCC, FG
L-(+)-Tartaric acid, p.a., ACS reagent, 99.0%
L-(+)-Tartaric acid, Vetec(TM) reagent grade, 99%
Q18226455
F8880-9012
Z1147451717
BUTANEDIOIC ACID, 2,3-DIHYDROXY-, (R-(R*,R*))-
Butanedioic acid, 2,3-dihydroxy-, (theta,theta)-(+-)-
000189E3-11D0-4B0A-8C7B-31E02A48A51F
L-(+)-Tartaric acid, puriss. p.a., ACS reagent, >=99.5%
L-(+)-Tartaric acid, certified reference material, TraceCERT(R)
Tartaric acid, United States Pharmacopeia (USP) Reference Standard
L-(+)-Tartaric acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.5%
L-(+)-Tartaric acid, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.5%
Tartaric Acid, Pharmaceutical Secondary Standard; Certified Reference Material
L-(+)-Tartaric acid, puriss. p.a., reag. ISO, reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)
L-(+)-Tartaric acid, puriss., meets analytical specification of Ph. Eur., BP, NF, FCC, E334, 99.7-100.5% (calc. to the dried substance), grit
L-(+)-Tartaric acid, puriss., meets analytical specification of Ph. Eur., NF, 99.7-100.5% (calc. to the dried substance), powder
L TARTARIC ACID
LABSA; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique; cas no: 27176-87-0
L-(-)-MALIC ACID
L-(-)-Malic acid is a dicarboxylic acid that is commonly found in fruits, particularly in apples, and is responsible for their sour taste.
L-(-)-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste.
L-(-)-Malic acid is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.

CAS Number: 97-67-6
Molecular Formula: C4H6O5
Molecular Weight: 134.09
EINECS Number: 202-601-5

Synonyms: 97-67-6, L-Malic acid, L-(-)-Malic acid, (S)-2-hydroxysuccinic acid, (2S)-2-Hydroxybutanedioic acid, (S)-Malic acid, L(-)-Malic acid, (-)-Malic acid, L-Apple acid, L-Hydroxybutanedioic acid, Apple acid, (-)-Hydroxysuccinic acid, L-malate, S-(-)-Malic acid, S-2-Hydroxybutanedioic acid, Butanedioic acid, hydroxy-, (2S)-, Malic acid, L-, L-2-Hydroxybutanedioic acid, CHEBI:30797, (-)-L-Malic acid, (S)-malate, MFCD00064213, Malic acid L-(-)-form, Hydroxysuccinnic acid (-), L-Hydroxysuccinic acid, J3TZF807X5, (S)-(-)-Hydroxysuccinic acid, CHEMBL1234046, NSC9232, (S)-(-)-2-Hydroxysuccinic acid, NSC-9232, NSC 9232, Butanedioic acid, 2-hydroxy-, (2S)-, (S)-Hydroxybutanedioic acid, (-)-(S)-Malic acid, Hydroxybutanedioic acid, (-)-, UNII-J3TZF807X5, malic-acid, Hydroxybutanedioic acid, (S)-, 2yfa, 4elc, 4ipi, 4ipj, L-Hydroxysuccinate, 2-Hydroxybutanedioic acid, (S)-, (2s)-malic acid, EINECS 202-601-5, L-Hydroxybutanedioate, nchembio867-comp7, L-(-) malic acid, (-)-Hydroxysuccinate, L-(-)-Apple Acid, S-(-)-Malate, (S)-Hydroxybutanedioate, S-2-Hydroxybutanedioate, (-)-(S)-Malate, (S)-(-)-malic acid, (S)-hydroxy-Butanedioate, (S)-Hydroxysuccinic acid, L(-)MALIC ACID, (S)-2-hydroxysuccinicacid, bmse000238, MALIC ACID [HSDB], MALIC ACID, (L), (S)-(-)-Hydroxysuccinate, L-MALIC ACID [FHFI], (S)-hydroxy-Butanedioic acid, SCHEMBL256122, L-MALIC ACID [WHO-DD], MALIC ACID, L- [II], (-)-(s)-hydroxybutanedioic acid, DTXSID30273987, (2S)-(-)-hydroxybutanedioic acid, AMY40197, HY-Y1069, BDBM50510127, s6292, AKOS006346693, CS-W020132, MALIC ACID L-(-)-FORM [MI], L-(-)-Malic acid, BioXtra, >=95%, AS-18628, L-(-)-Malic acid, >=95% (titration), (S)-E 296, (-)-1-Hydroxy-1,2-ethanedicarboxylic acid, M0022, NS00068391, EN300-93424, C00149, L-(-)-Malic acid, purum, >=99.0% (T), L-(-)-Malic acid, ReagentPlus(R), >=99%, M-0850, 35F9ECA9-BBE6-463D-BF3F-275FACC5D14E, L-(-)-Malic acid, SAJ special grade, >=99.0%, L-(-)-Malic acid, Vetec(TM) reagent grade, 97%, Q27104150, Z1201618618, (S)-(-)-2-Hydroxysuccinic acid, L-Hydroxybutanedioic acid, L-(-)-Malic acid, 97%, optical purity ee: 99% (GLC), L-(-)-Malic acid, certified reference material, TraceCERT(R), L-(-)-Malic acid, BioReagent, suitable for cell culture, suitable for insect cell culture, 26999-59-7

L-(-)-Malic acid is an organic compound with the molecular formula HO2CCH(OH)CH2CO2H.
L-(-)-Malic acid is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive.
L-(-)-Malic acid has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally.

The salts and esters of L-(-)-Malic acid are known as malates.
The malate anion is a metabolic intermediate in the citric acid cycle.
L-(-)-Malic acid is a naturally occurring organic compound with the molecular formula C4H6O5.

L-(-)-Malic acid is nearly odorless (sometimes a faint, acrid odor).
L-(-)-Malic acid has a tart, acidic, nonpungent taste.
L-(-)-Malic acid is an organic acid that is commonly found in wine.

L-(-)-Malic acid plays an important role in wine microbiological stability.
L-(-)-Malic acid is a part of cellular metabolism.
Its application is recognized in pharmaceutics.

L-(-)-Malic acid is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia.
L-(-)-Malic acid is used as a part of amino acid infusion.
L-(-)-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders.

L-(-)-Malic acid intermediate and partner in the malic acid aspartate shuttle.
Crystallise L-(-)-Malic acid from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o.
Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point.

L-(-)-Malic acid, a hydroxydicarboxylic acid, is found in all forms of life.
L-(-)-Malic acid exists naturally only as the L-enantiomer.
L-(-)-Malic acid should not be confused with the similar sounding maleic and malonic acids.

L-(-)-Malic acid gives many fruits, particularly apples, their characteristic flavor.
It is often referred to as “apple acid”.
The word malic is derived from the Latin mālum, for which Malus, the genus that contains all apple species, is also named.

The word 'L-(-)-Malic acid' is derived from Latin mālum, meaning 'apple'. The related Latin word mālus, meaning 'apple tree', is used as the name of the genus Malus, which includes all apples and crabapples; and is the origin of other taxonomic classifications such as Maloideae, Malinae, and Maleae.
L-(-)-Malic acid is the naturally occurring form, whereas a mixture of L- and D-malic acid is produced synthetically.

Malate plays an important role in biochemistry.
In the C4 carbon fixation process, malate is a source of CO2 in the Calvin cycle.
In the L-(-)-Malic acid, (S)-malate is an intermediate, formed by the addition of an -OH group on the si face of fumarate.

L-(-)-Malic acid can also be formed from pyruvate via anaplerotic reactions.
L-(-)-Malic acid is also synthesized by the carboxylation of phosphoenolpyruvate in the guard cells of plant leaves.
L-(-)-Malic acid, as a double anion, often accompanies potassium cations during the uptake of solutes into the guard cells in order to maintain electrical balance in the cell.

The accumulation of these solutes within the guard cell decreases the solute potential, allowing water to enter the cell and promote aperture of the stomata.
L-(-)-Malic acid was first isolated from apple juice by Carl Wilhelm Scheele in 1785.
Antoine Lavoisier in 1787 proposed the name acide malique, which is derived from the Latin word for apple, mālum—as is its genus name Malus.

In German it is named Äpfelsäure (or Apfelsäure) after plural or singular of a sour thing from the apple fruit, but the salt(s) are called Malat(e).
L-(-)-Malic acid is the main acid in many fruits, including apricots, blackberries, blueberries, cherries, grapes, mirabelles, peaches, pears, plums, and quince, and is present in lower concentrations in other fruits, such as citrus.
L-(-)-Malic acid contributes to the sourness of unripe apples. Sour apples contain high proportions of the acid.

L-(-)-Malic acid is present in grapes and in most wines with concentrations sometimes as high as 5 g/L.
L-(-)-Malic acid confers a tart taste to wine; the amount decreases with increasing fruit ripeness.
The taste of malic acid is very clear and pure in rhubarb, a plant for which it is the primary flavor.

L-(-)-Malic acid is also the compound responsible for the tart flavor of sumac spice.
L-(-)-Malic acid is also a component of some artificial vinegar flavors, such as "salt and vinegar" flavored potato chips.
L-(-)-Malic acid is produced industrially by the double hydration of maleic anhydride.

In 2000, American production capacity was 5,000 tons per year.
The enantiomers may be separated by chiral resolution of the racemic mixture.
L-(-)-Malic acid is obtained by fermentation of fumaric acid.

Self-condensation of malic acid in the presence of fuming sulfuric acid gives the pyrone coumalic acid: 2 HO2CCH(OH)CH2CO2H → HO2CC4H3O2 + 2 CO + 4 H2O
Carbon monoxide and water are liberated during this reaction.
L-(-)-Malic acid was important in the discovery of the Walden inversion and the Walden cycle, in which (−)-malic acid first is converted into (+)-chlorosuccinic acid by action of phosphorus pentachloride.

Wet silver oxide then converts the chlorine compound to L-(-)-Malic acid, which then reacts with PCl5 to the (−)-chlorosuccinic acid.
The cycle is completed when silver oxide takes this compound back to (−)-malic acid.
L-(-)-Malic acid is used to resolve α-phenylethylamine, a versatile resolving agent in its own right.

L-(-)-Malic acid is also found in plants and animals, including humans.
In fact, L-(-)-Malic acid, in the form of its anion malate, is a key intermediate in the major biochemical energy-producing cycle in cells known as the citric acid or Krebs cycle located in the cells' mitochondria.
L-(-)-Malic acid is used in many food products and is a very popular product in beverages and sweets.

L-(-)-Malic acid, also known as apple acid and hydroxysuccinic acid, is a chiral molecule.
L-(-)-Malic acid contains natural emollient ingredients, which can remove wrinkles on the skin surface, make the skin become tender and white, smooth and elastic, so in the cosmetic formula favored; L-malic acid can be formulated a variety of flavors, spices, for a variety of daily chemical products, such as toothpaste, shampoo, etc; it is used abroad to replace citric acid as a new type of detergent additive for the synthesis of high-grade special detergents.
L-(-)-Malic acid can be used in pharmaceutical preparations, tablets, syrup, can also be mixed into the amino acid solution, can significantly improve the absorption rate of amino acids; L-malic acid can be used for the treatment of liver disease, anemia, low immunity, uremia, hypertension, liver failure and other diseases, and can reduce the toxic effect of anticancer drugs on normal cells; Can also be used for the preparation and synthesis of insect repellents, anti-Tartar agents.

In addition, L-(-)-Malic acid can also be used as industrial cleaning agent, resin curing agent, synthetic material plasticizer, feed additive, etc.
L-(-)-Malic acid is a part of cellular metabolism.
L-(-)-Malic acid's application is recognized in pharmaceutics.

L-(-)-Malic acid is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia.
L-(-)-Malic acid is used as a part of amino acid infusion.
L-(-)-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders.

A TCA (Krebs cycle) intermediate and partner in the L-Malic acid aspartate shuttle.
L-(-)-Malic acid is the naturally occurring form, whereas a mixture of L- and D-malic acid is produced synthetically.
Malate plays an important role in biochemistry.

In the C4 carbon fixation process, malate is a source of CO2 in the Calvin cycle.
In the L-(-)-Malic acid cycle, (S)-malate is an intermediate, formed by the addition of an -OH group on the si face of fumarate.
L-(-)-Malic acid can also be formed from pyruvate via anaplerotic reactions.

L-(-)-Malic acid is also synthesized by the carboxylation of phosphoenolpyruvate in the guard cells of plant leaves.
L-(-)-Malic acid, as a double anion, often accompanies potassium cations during the uptake of solutes into the guard cells in order to maintain electrical balance in the cell.
The accumulation of these solutes within the guard cell decreases the solute potential, allowing water to enter the cell and promote aperture of the stomata.

L-(-)-Malic acid, a four-carbon dicarboxylic acid, is widely used in the food, chemical and medical industries.
As an intermediate of the TCA cycle, L-(-)-Malic acid is one of the most promising building block chemicals that can be produced from renewable sources.
To date, chemical synthesis or enzymatic conversion of petrochemical feedstocks are still the dominant mode for malic acid production.

However, with increasing concerns surrounding environmental issues in recent years, microbial fermentation for the production of L-(-)-Malic acid was extensively explored as an eco-friendly production process.
The rapid development of genetic engineering has resulted in some promising strains suitable for large-scale bio-based production of L-(-)-Malic acid.
This review offers a comprehensive overview of the most recent developments, including a spectrum of wild-type, mutant, laboratory-evolved and metabolically engineered microorganisms for malic acid production.

The technological progress in the fermentative production of L-(-)-Malic acid is presented. Metabolic engineering strategies for malic acid production in various microorganisms are particularly reviewed.
Biosynthetic pathways, transport of malic acid, elimination of byproducts and enhancement of metabolic fluxes are discussed and compared as strategies for improving malic acid production, thus providing insights into the current state of malic acid production, as well as further research directions for more efficient and economical microbial L-(-)-Malic acid production.

Melting point: 101-103 °C (lit.)
alpha: -2 º (c=8.5, H2O)
Boiling point: 167.16°C (rough estimate)
Density: 1.60
vapor pressure: 0Pa at 25℃
FEMA: 2655 | L-MALIC ACID
refractive index: -6.5 ° (C=10, Acetone)
Flash point: 220 °C
storage temp.: Store below +30°C.
solubility: H2O: 0.5 M at 20 °C, clear, colorless
form: Powder
color: White
Specific Gravity: 1.595 (20/4℃)
Odor: odorless
PH: 2.2 (10g/l, H2O, 20℃)
pka: (1) 3.46, (2) 5.10(at 25℃)
Odor Type: odorless
optical activity: [α]20/D 30±2°, c = 5.5% in pyridine
Water Solubility: soluble
Merck: 14,5707
JECFA Number: 619
BRN: 1723541
InChIKey: BJEPYKJPYRNKOW-REOHCLBHSA-N
LogP: -1.68

L-(-)-Malic acid is used as Selective α-amino protecting reagent for amino acid derivatives.
Versatile synthon for the preparation of chiral compounds including κ-opioid rece.
L-(-)-Malic acid also acts as active ingredient in many sour or tart foods.

L-(-)-Malic acid is used as synthesizing disincrustant and fluorescent whitening agent.
L-(-)-Malic acid aids in the production of polyester and alcohol acid resins.
L-(-)-Malic acid is an organic acid that is commonly found in wine.

L-(-)-Malic acid plays an important role in wine microbiological stability.
L-(-)-Malic acid has a chemical structure where a hydroxyl group (-OH) is attached to the second carbon of butanedioic acid, with the L-configuration indicating its specific stereochemistry.
The "L-(-)" notation indicates that it is the levorotatory (left-rotating) isomer of malic acid, which means it rotates plane-polarized light to the left.

In biology, L-(-)-Malic acid plays a crucial role in the citric acid cycle (Krebs cycle), which is essential for cellular respiration in plants, animals, and microorganisms.
L-(-)-Malic acid is used in the food and beverage industry as an acidulant, to add tartness and enhance flavors.
L-(-)-Malic acid is also used in cosmetics and pharmaceuticals.

L-(-)-Malic acid is a white crystalline powder that is highly soluble in water.
L-(-)-Malic acids CAS number is 97-67-6, and it has various synonyms, including (S)-2-hydroxybutanedioic acid, L-Apple acid, and L-Hydroxybutanedioic acid.
L-(-)-Malic acid is a selective α-amino protecting reagent for amino acid derivatives.

L-(-)-Malic acid is also a versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
An acid of natural origin contained in most fruit (L-malic acid) or synthetically made: DL-malic.
L-(-)-Malic acid is used for the acidification of musts and wines in the conditions set by the regulation.

L-(-)-Malic acid is a white, odorless, crystalline solid. In contrast to other fruit acids, it is very hygroscopic and has a tendency to lump.
L-(-)-Malic acid is a dicarboxylic acid and has an asymmetric carbon and occurs as l(the natural)- and d-isomers.
L-(-)-Malic acid is an organic dicarboxylic acid that is present in various foods and is metabolized in humans through the Krebs (or citric acid) cycle.

In its stable isotope-labeled form, it is commonly used as an authentic standard for metabolite quantification.
L-(-)-Malic acid is nearly odorless with a tart, acidic taste.
L-(-)-Malic acid is nonpungent.

L-(-)-Malic acid is an organic acid that is commonly found in wine.
L-(-)-Malic acid plays an important role in wine microbiological stability.
L-(-)-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.

Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
L-(-)-Malic acid is an organic compound with the molecular formula C4H6O5.
L-(-)-Malic acid is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive.

L-(-)-Malic acid has two stereoisomeric forms (L- and D-enantiomers), though only the L-isomer exists naturally.
The salts and esters of L-Malic acid are known as malates.
The malate anion is an intermediate in the citric acid cycle.

L-(-)-Malic acid, a hydroxydicarboxylic acid, is found in all forms of life.
L-(-)-Malic acid exists naturally only as the L-enantiomer.
L-(-)-Malic acid should not be confused with the similar sounding maleic and malonic acids.

L-(-)-Malic acid is L-hydroxysuccinic acid, by enzyme engineering method or fermentation method and separation and purification.
The content of C4H6Os shall not be less than 99.0% calculated as anhydrous.
L-(-)-Malic acid gives many fruits, particularly apples, their characteristic flavor.

L-(-)-Malic acid is often referred to as “apple acid”.
The word malic is derived from the Latin malum, for which Malus, the genus that contains all apple species, is also named.
L-(-)-Malic acid is a dicarboxylic acid that is found in many fruits and vegetables.

L-(-)-Malic acid is the substrate for the enzyme malate dehydrogenase, which catalyzes the oxidation of L-malate to oxaloacetate.
L-(-)-Malic acid is used to study mitochondrial function, as it can be used as an alternative energy source.
The L-(-)-Malic acid monosodium salt (LAM) has been shown to be effective in preventing muscle damage caused by exercise.

This may be due to L-(-)-Malic acid's ability to decrease oxidative stress and increase ATP production through increased mitochondrial activity.
L-(-)-Malic acid also has been shown to promote photoreceptor cell survival and improve retinal function in animals with damaged photoreceptors, although it does not have any effect on normal animal eyes.

L-(-)-Malic acid, is an alpha-hydroxy organic acid, is sometimes referred to as a fruit acid.
L-(-)-Malic acid is found in apples and other fruits.

Uses:
L-(-)-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives.
Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants.

L-(-)-Malic acid selective α-amino protecting reagent for amino acid derivatives.
Versatile synthon for the preparation of chiral compounds including κ-opioid rece
Intermediate in chemical synthesis.

L-(-)-Malic acid is used as Selective α-amino protecting reagent for amino acid derivatives.
Versatile synthon for the preparation of chiral compounds including κ-opioid rece.
L-(-)-Malic acid also acts as active ingredient in many sour or tart foods.

L-(-)-Malic acid is used as synthesizing disincrustant and fluorescent whitening agent.
L-(-)-Malic acid aids in the production of polyester and alcohol acid resins.
L-(-)-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives.

Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants.
Selective α-amino protecting reagent for amino acid derivatives.

L-(-)-Malic acid flavoring agent, flavor enhancer and acidulant in foods.
L-(-)-Malic acid may improve exercise performance by boosting energy and decreasing muscle fatigue.
L-(-)-Malic acid also enhances the absorption of other sports performance enhancers like creatine and citrulline.

One study found that a creatine-malate combination improved several aspects of athletes’ running performance, including peak power, distance traveled, hormone levels, and total work.
Bonding L-(-)-Malic acid with citrulline produces citrulline malate.
The L-(-)-Malic acid enhances citrulline’s innate ability to improve nitric oxide levels, remove muscle waste, increase energy, and reduce muscle soreness.

L-(-)-Malic acid may improve dry mouth, dry mouth caused by medication in particular.
L-(-)-Malic acid helps produce more saliva due to its sour flavor.
One six-week study examined the effects of a L-(-)-Malic acid spray solution on dry mouth compared to a placebo.

The L-(-)-Malic acid group had noticeably improved dry mouth symptoms and better saliva flow than the placebo group.
Another two-week trial produced similar results.
Most individuals tolerate L-(-)-Malic acid well, given that L-Malic acid’s a common compound in many fruits and vegetables.

L-(-)-Malic acid may cause mild side effects, including nausea, diarrhea, and headaches.
Individuals taking medications to lower their blood pressure should consult with a physician before taking malic acid supplements, as they may lower blood pressure.
Kidney stones are painful and can affect many people.

L-(-)-Malic acid has been researched for its potential role in preventing and treating kidney stones.
L-(-)-Malic acid is commonly used as an acidulant to enhance the sour taste in foods and beverages, such as fruit juices, candies, soft drinks, and wines.
L-(-)-Malic acids acidic nature helps preserve food by inhibiting the growth of bacteria and other microorganisms.

L-(-)-Malic acid is used to adjust and stabilize the pH levels in various food products.
L-(-)-Malic acid is used in cosmetic products for its exfoliating properties, helping to remove dead skin cells and promote skin renewal.
L-(-)-Malic acid is included in anti-aging formulations to improve skin texture and appearance.

L-(-)-Malic acid is used in dietary supplements to support energy production and improve exercise performance.
L-(-)-Malic acid can act as an excipient in pharmaceutical formulations, helping to stabilize the active ingredients and improve their absorption.
L-(-)-Malic acid can be used to adjust the pH of soil, making it more suitable for growing certain crops.

L-(-)-Malic acid may be included in fertilizers to enhance nutrient availability to plants.
L-(-)-Malic acid is used in metal cleaning and treatment processes for its ability to remove rust and scale from metal surfaces.
It serves as an intermediate in the synthesis of various chemicals and pharmaceuticals.

L-(-)-Malic acid is used in some toothpaste and mouthwash formulations for its ability to stimulate saliva production and help reduce dry mouth.
It may be used in treatments for conditions like fibromyalgia, where it is believed to help improve energy production and reduce muscle pain.
L-(-)-Malic acid is naturally present in grapes and is involved in the malolactic fermentation process, which softens the taste of wine by converting malic acid to lactic acid.

L-(-)-Malic acid is used to enhance the tartness and balance the sweetness of apple cider.
Added to carbonated beverages to provide a tangy flavor.
L-(-)-Malic acid is used in hard and soft candies to provide a sharp, tart taste.

Enhances the sour flavor profile and improves the overall taste experience.
Helps in maintaining the freshness of baked goods by controlling the pH and acting as a preservative.
Adds a subtle tartness to pastries, cakes, and other baked items.

L-(-)-Malic acid is used to enhance the tangy flavor of yogurt and other cultured dairy products.
Helps in the acidification process during cheese making.
Included in hair care products to adjust the pH and enhance the cleaning and conditioning properties.

L-(-)-Malic acid acts as a humectant, helping to retain moisture in the skin.
Adds a refreshing and invigorating scent and feel to bath products.
L-(-)-Malic acid is used in formulations to help exfoliate the skin and reduce acne breakouts.

Included in some wound care products for its moisturizing and pH-adjusting properties.
Often included in formulations aimed at improving energy levels and reducing fatigue, particularly for athletes.
L-(-)-Malic acid is used in various cleaning products for its ability to remove mineral deposits and scale.

Helps in cleaning metal parts and surfaces in industrial settings.
L-(-)-Malic acid is used a plasticizer in the production of certain types of plastics and resins to improve their flexibility and durability.
L-(-)-Malic acid is used in formulations to help break down mucus and improve respiratory function.

Included in creams and ointments for muscle and joint pain relief.
L-(-)-Malic acid is used as a feed additive to improve the taste and nutritional value of animal feed.
Sometimes included in pesticide formulations to enhance their effectiveness.

L-(-)-Malic acid is used in the textile industry to fix dyes and improve the colorfastness of fabrics.
L-(-)-Malic acid is used to adjust the pH of water in various water treatment processes.
Included in formulations for biodegradable and eco-friendly products due to its natural origin and low environmental impact.

Added to protein bars and powders to enhance flavor and improve stability.
L-(-)-Malic acid is used in sports and electrolyte drinks to balance acidity and improve taste.
Helps maintain the desired pH level and enhance the preservation of canned fruits and vegetables.

Adds a tangy flavor to sauces, dressings, and marinades.
L-(-)-Malic acid is used as a fixative in perfumes to enhance the longevity of fragrances.
Adds a refreshing scent to various personal care products.

Included in toothpaste formulations to help remove plaque and promote oral hygiene.
Enhances the flavor and freshness of mouthwash.
L-(-)-Malic acid is used as a stabilizer in pharmaceutical formulations to enhance the shelf life and efficacy of active ingredients.

Helps maintain the pH of pharmaceutical products for better stability and absorption.
Added to medical foods designed for specific dietary needs, such as for patients with metabolic disorders.
L-(-)-Malic acid is used in the production of adhesives and sealants to improve their properties and performance.

Utilized in the paper and pulp industry as a component in the bleaching process to enhance the whiteness of paper.
L-(-)-Malic acid is used in oral rehydration solutions to balance electrolytes and improve hydration.
Incorporated into transdermal patches for its role in enhancing the absorption of active ingredients through the skin.

L-(-)-Malic acid is used in the formulation of fertilizers to adjust the pH and enhance nutrient availability to plants.
Acts as a synergist in pesticide formulations to improve their efficacy against pests.
L-(-)-Malic acid is used in bioremediation processes to enhance the breakdown of pollutants in the environment.

Incorporated into environmentally friendly products due to its natural origin and biodegradability.
L-(-)-Malic acid is used as an additive in battery electrolytes to improve performance and stability.
Included in 3D printing materials to enhance their properties and performance.

L-(-)-Malic acid is used in the formulation of ceramic glazes to improve their quality and appearance.
Enhances the uptake and vibrancy of dyes in textile dyeing processes.

L-(-)-Malic acid is used as a modifier in the production of biodegradable polymers to improve their properties.
Included in electrolyte formulations for electronic components to enhance their performance.

Safety Profile:
While L-(-)-Malic acid is not highly flammable, it can burn if exposed to a strong ignition source.
Direct contact with L-(-)-Malic acid can cause irritation, redness, and discomfort. Prolonged exposure may lead to more severe skin conditions.
L-(-)-Malic acid comes into contact with the eyes, it can cause irritation, redness, pain, and potentially damage the eye tissue.

Inhaling dust or vapors of L-(-)-Malic acid can cause respiratory tract irritation, leading to coughing, sore throat, and shortness of breath.
Ingesting large amounts of L-(-)-Malic acid can cause gastrointestinal irritation, resulting in symptoms like nausea, vomiting, and abdominal pain.

L-(-)-Malic acid can be harmful to aquatic life if large quantities enter water bodies.
L-(-)-Malic acid may cause changes in water pH, which can affect aquatic organisms.


L-(-)-MALIC ACID

L-(-)-Malic acid, also known simply as malic acid, is a naturally occurring organic compound.
L-(-)-Malic acid belongs to the class of dicarboxylic acids, characterized by having two carboxyl groups (COOH) attached to a carbon chain.
Malic acid is optically active, meaning it can exist in two enantiomeric forms: L-malic acid and D-malic acid.

CAS Number: 97-67-6
EC Number: 202-601-5

Malic acid, L-malic acid, D-malic acid, Hydroxybutanedioic acid, 2-Hydroxybutanedioic acid, 2-Hydroxysuccinic acid, (S)-Hydroxysuccinic acid, (S)-Malic acid, (S)-2-Hydroxybutanedioic acid, (-)-Malic acid, (2S)-Hydroxybutanedioic acid, L-Hydroxysuccinic acid, (2S)-Malic acid, L-2-Hydroxybutanedioic acid, (S)-2-Hydroxysuccinic acid, (2S)-2-Hydroxysuccinic acid, (S)-2-Hydroxybutanedioic acid, 2-Hydroxybutanedioate, Hydroxysuccinic acid, (+)-Malic acid, L-Malate, (-)-Hydroxysuccinic acid, L-Malic acid, L-Malate, (-)-Malate, L-Hydroxysuccinic acid, Malate, (-)-Hydroxybutanedioic acid, (-)-2-Hydroxybutanedioic acid, Malic acid, hydroxybutanedioic acid, (S)-2-Hydroxybutanedioic acid, Malic acid, hydroxybutanedioic acid



APPLICATIONS


L-(-)-Malic acid is commonly used as a food additive in the food industry.
L-(-)-Malic acid serves as a flavor enhancer and acidulant in beverages, candies, and processed foods.

L-(-)-Malic acid is added to sour candies to impart a tart taste.
L-(-)-Malic acid is used in the production of carbonated beverages to provide acidity and enhance flavor.
L-(-)-Malic acid is employed as an acidulant in fruit juices and fruit-flavored drinks.

L-(-)-Malic acid is used in the fermentation process of alcoholic beverages such as cider and wine.
L-(-)-Malic acid is added to sports and energy drinks for its refreshing and tart flavor.

L-(-)-Malic acid is used as a preservative in canned fruits and vegetables to maintain their freshness.
L-(-)-Malic acid is utilized in the production of baking powder and sourdough bread.

L-(-)-Malic acid is added to certain dairy products such as yogurt and cheese for flavor enhancement.
L-(-)-Malic acid is used in the pharmaceutical industry as an ingredient in medications.

L-(-)-Malic acid is employed in the formulation of chewable tablets and effervescent powders.
L-(-)-Malic acid is used in oral care products such as mouthwashes and toothpaste.
L-(-)-Malic acid is added to skincare products for its exfoliating and rejuvenating properties.

L-(-)-Malic acid is utilized in hair care products such as shampoos and conditioners.
L-(-)-Malic acid is employed in the textile industry for dyeing and finishing processes.
L-(-)-Malic acid is used in the production of biodegradable plastics and polymers.

L-(-)-Malic acid is employed in the manufacturing of cleaning agents and detergents.
L-(-)-Malic acid is used in agricultural applications as a soil conditioner.
L-(-)-Malic acid is added to animal feed as a nutritional supplement.

L-(-)-Malic acid is used in the production of adhesives and sealants.
L-(-)-Malic acid is employed in the formulation of industrial coatings and paints.
L-(-)-Malic acid is used in the production of metal cleaners and rust removers.

L-(-)-Malic acid is utilized in the manufacturing of paper and pulp products.
Overall, L-(-)-Malic acid has a wide range of applications across various industries, contributing to its versatility and importance in the global market.

L-(-)-Malic acid is utilized in the production of dietary supplements and vitamin formulations.
It is added to fruit-flavored gummies and chewable vitamins for taste enhancement.
L-(-)-Malic acid is used in the cosmetic industry as an ingredient in skincare masks and peels.

L-(-)-Malic acid is employed in exfoliating scrubs and treatments to remove dead skin cells and improve skin texture.
L-(-)-Malic acid is utilized in anti-aging serums and creams for its skin-renewing properties.

L-(-)-Malic acid is added to facial toners and astringents to balance pH levels and tighten pores.
L-(-)-Malic acid is used in hair color products as a pH adjuster and conditioner.
L-(-)-Malic acid helps to open the hair cuticle, allowing for better penetration of color molecules.

L-(-)-Malic acid is employed in the production of flavorings and extracts for the food industry.
L-(-)-Malic acid is used in the formulation of fruit syrups, jams, and jellies for its natural tartness.
L-(-)-Malic acid is utilized in the brewing industry to adjust the acidity of beer and cider.

It contributes to the flavor profile and balance of sourness in fermented beverages.
L-(-)-Malic acid is added to marinades and sauces for meat tenderization and flavor enhancement.
It helps to break down proteins and infuse flavor into the meat during cooking.

L-(-)-Malic acid is used in the production of confectionery such as sour candies and gummies.
L-(-)-Malic acid provides a tangy and refreshing taste that complements sweet and savory flavors.
L-(-)-Malic acid is employed in the formulation of nutritional sports drinks and electrolyte beverages.

L-(-)-Malic acid helps to replenish electrolytes lost during physical activity and improve hydration.
L-(-)-Malic acid is added to frozen desserts such as sorbets and sherbets for its tart flavor.
L-(-)-Malic acid enhances the fruitiness and brightness of fruit-based frozen treats.

L-(-)-Malic acid is utilized in the production of flavored water and fruit-infused beverages.
L-(-)-Malic acid adds a zesty and invigorating taste to plain water, encouraging hydration.
L-(-)-Malic acid is used in the pharmaceutical industry to mask the bitterness of medications.

L-(-)-Malic acid improves the palatability of oral suspensions and liquid medications.
Overall, L-(-)-Malic acid plays a crucial role in various industries, contributing to the flavor, texture, and efficacy of a wide range of products.



DESCRIPTION


L-(-)-Malic acid, also known simply as malic acid, is a naturally occurring organic compound.
L-(-)-Malic acid belongs to the class of dicarboxylic acids, characterized by having two carboxyl groups (COOH) attached to a carbon chain.
Malic acid is optically active, meaning it can exist in two enantiomeric forms: L-malic acid and D-malic acid.
The L-(-)-malic acid isomer is the biologically active form found in living organisms.

Chemically, L-(-)-malic acid has the molecular formula C4H6O5 and a molar mass of approximately 134.09 grams per mole.
Its structure consists of a four-carbon chain with two carboxyl groups (COOH) and one hydroxyl group (OH).

L-(-)-Malic acid is commonly found in various fruits, particularly in apples, where it contributes to the sour taste.
L-(-)-Malic acid is also present in other fruits like grapes, cherries, and citrus fruits, as well as in certain vegetables.
In addition to its natural occurrence, L-(-)-malic acid is used as a food additive for its tart flavor and preservative properties.
L-(-)-Malic acid is commonly added to foods and beverages as an acidulant, flavor enhancer, or pH regulator.

L-(-)-Malic acid is a naturally occurring organic compound.
L-(-)-Malic acid is classified as a dicarboxylic acid due to its two carboxyl groups.

The chemical formula of L-(-)-Malic acid is C4H6O5.
L-(-)-Malic acid is optically active and exists in the L-form in biological systems.

L-(-)-Malic acid is a white, crystalline solid at room temperature.
L-(-)-Malic acid has a tart taste and is commonly found in sour fruits such as apples.

The acid has a melting point of approximately 130-131°C.
L-(-)-Malic acid is soluble in water and alcohol.
L-(-)-Malic acid is odorless and typically has a sour or acidic smell.

L-(-)-Malic acid is often used as a food additive for its sour flavor.
L-(-)-Malic acid is also used as a flavor enhancer and acidulant in the food industry.
L-(-)-Malic acid plays a role in the Krebs cycle, a key metabolic pathway in cells.

It is involved in the production of energy through the metabolism of carbohydrates.
L-(-)-Malic acid is commonly found in various fruits and vegetables.
L-(-)-Malic acid contributes to the tartness of certain wines and beverages.

L-(-)-Malic acid is used in the production of cosmetics and personal care products.
It has exfoliating properties and is often found in skincare formulations.

L-(-)-Malic acid is also used in pharmaceuticals as an ingredient in medications.
L-(-)-Malic acid has been studied for its potential health benefits, including antioxidant properties.

L-(-)-Malic acid is biodegradable and environmentally friendly.
L-(-)-Malic acid is stable under normal conditions of storage and handling.

L-(-)-Malic acid can be synthesized from fumaric acid or maleic acid.
L-(-)-Malic acid has a role in the acidity of certain fermented foods and beverages.

L-(-)-Malic acid is considered safe for consumption in appropriate quantities.
Overall, L-(-)-Malic acid is a versatile compound with various applications in food, pharmaceutical, and cosmetic industries.



PROPERTIES


Chemical Formula: C4H6O5
Molecular Weight: Approximately 134.09 grams per mole
Physical State: Solid at room temperature (crystalline)
Color: White
Odor: Odorless
Taste: Tart or sour
Solubility in Water: Soluble
Solubility in Organic Solvents: Soluble in ethanol, methanol, and other polar organic solvents
Melting Point: Approximately 130-131°C
Boiling Point: Decomposes before boiling
Density: Approximately 1.609 g/cm³
pH: Acidic (approximately 2.2 at 1% solution)
Optical Activity: Optically active (L-form)
Hygroscopicity: Low
Stability: Stable under normal conditions
Flammability: Non-flammable
Refractive Index: Approximately 1.561
Dielectric Constant: Approximately 2.3
Heat of Combustion: Approximately -1025 kJ/mol
Heat of Fusion: Approximately 21.1 kJ/mol
Heat of Vaporization: Approximately 70.5 kJ/mol
Specific Heat Capacity: Approximately 0.925 J/g°C
Flash Point: Not applicable (solid)
Surface Tension: Approximately 82.0 mN/m
Viscosity: Varies with concentration and temperature



FIRST AID


Inhalation:

If inhaled, remove the affected person to fresh air immediately.
Allow the person to rest in a well-ventilated area.
If breathing difficulties persist, seek medical attention promptly.
Provide oxygen if the person has difficulty breathing.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected area with plenty of soap and water for at least 15 minutes.
Rinse skin thoroughly to remove any traces of the substance.
If irritation, redness, or rash develops, seek medical advice.
Apply a soothing moisturizer or barrier cream to the affected area to help alleviate discomfort.


Eye Contact:

Flush eyes with lukewarm water, keeping eyelids open, for at least 15 minutes.
Remove contact lenses if present and easily removable.
Seek immediate medical attention if irritation, pain, or redness persists.
Protect the unaffected eye to prevent contamination.


Ingestion:

Rinse mouth with water and drink plenty of water to dilute the substance.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek medical attention immediately and provide information on the ingested substance.
Do not give anything by mouth to an unconscious person.


General Advice:

Keep affected person calm and reassure them.
If seeking medical attention, provide the Safety Data Sheet (SDS) or product label information to healthcare providers.
If the substance has entered the respiratory tract, monitor for signs of respiratory distress and administer CPR if necessary.
Do not administer any medications unless directed by medical personnel.
If exposed to large quantities or experiencing severe symptoms, seek emergency medical assistance immediately.
Be prepared to provide information on the specific product, concentration, and duration of exposure when seeking medical advice.
If transporting an affected individual to a medical facility, ensure proper ventilation and monitor their condition closely.


Additional Precautions:

Avoid direct skin contact with L-(-)-Malic acid, especially in concentrated form.
Use appropriate personal protective equipment (PPE) such as gloves, safety glasses, and protective clothing when handling the substance.
Handle L-(-)-Malic acid in a well-ventilated area to minimize inhalation exposure.
Store L-(-)-Malic acid in a tightly sealed container away from incompatible materials.
Dispose of L-(-)-Malic acid according to local regulations and guidelines.



HANDLING AND STORAGE


Handling:

General Handling:
Handle L-(-)-Malic acid with care to prevent spills and minimize dust generation.
Use appropriate personal protective equipment (PPE) such as gloves, safety glasses, and protective clothing when handling.
Avoid inhalation of dust or vapors. Use in a well-ventilated area or use local exhaust ventilation if necessary.
Do not eat, drink, or smoke while handling L-(-)-Malic acid.
Wash hands thoroughly with soap and water after handling.

Spill and Leak Procedures:
In case of a small spill, collect the material using suitable absorbent material and place it in a labeled container for disposal.
Avoid sweeping or vacuuming the spilled material to prevent dispersion of dust.
Dispose of the collected material in accordance with local regulations.
For large spills or leaks, evacuate the area and contact appropriate authorities for cleanup and disposal.

Storage:
Store L-(-)-Malic acid in a cool, dry, well-ventilated area away from sources of heat, moisture, and ignition.
Keep containers tightly closed when not in use to prevent contamination and moisture absorption.
Store away from incompatible materials such as strong oxidizing agents and bases.
Ensure proper labeling of containers with product name, hazard warnings, and handling instructions.
Do not store near food, feed, or pharmaceuticals to avoid potential cross-contamination.

Handling Precautions:
Avoid prolonged or repeated skin contact with L-(-)-Malic acid.
Use appropriate engineering controls such as dust suppression or containment measures to minimize dust exposure.
Avoid contact with eyes and mucous membranes. In case of contact, rinse thoroughly with water.
Use caution when transferring or dispensing L-(-)-Malic acid to prevent spills and splashes.
Clean up any spills or leaks promptly and dispose of waste material properly.

Transportation:
Follow all applicable regulations and guidelines for the transportation of L-(-)-Malic acid.
Ensure containers are properly labeled, sealed, and secured to prevent leaks or spills during transportation.
Use suitable containers and packaging materials that are compatible with the chemical and designed for transportation purposes.

Emergency Procedures:
Familiarize yourself and other personnel with emergency procedures in case of accidental exposure, spill, or release.
Have appropriate spill control measures, personal protective equipment, and emergency contact information readily available.
In case of emergency, follow established procedures and notify relevant authorities for assistance.

L-(−)-MALIC ACID

L-(−)-Malic acid, also known simply as malic acid, is a naturally occurring organic compound with the chemical formula C4H6O5.
L-(−)-malic acid is a dicarboxylic acid, meaning it has two carboxylic acid functional groups (-COOH) in its structure.
Malic acid is chiral and exists in two enantiomeric forms: L-malic acid and D-malic acid.
The "L" designation refers to its specific optical rotation.

CAS Number: 97-67-6
EC Number: 201-791-2



APPLICATIONS


L-(−)-malic acid, also known simply as malic acid, has a wide range of applications across various industries due to its acidity, flavor-enhancing properties, and biological functions.
Here are some of its key applications:

Food and Beverage Industry:
L-(−)-malic acid is used as an acidulant and flavor enhancer in the production of beverages, including fruit juices, soft drinks, and sports drinks.
L-(−)-malic acid is a common ingredient in sour candies, fruit-flavored snacks, and confectionery items.
L-(−)-malic acid is utilized to provide tartness and acidity in fruit-flavored jams, jellies, and fruit preserves.
In the wine industry, L-(−)-malic acid levels are monitored and controlled during fermentation to influence wine acidity and flavor.

Food Additive:
L-(−)-malic acid is employed as a food additive (E number E296) to regulate acidity and enhance the taste of processed foods, such as canned fruits and vegetables, salad dressings, and sauces.
L-(−)-malic acid helps maintain the freshness and flavor of canned and packaged foods.

Cosmetic and Skincare Products:
L-(−)-malic acid is used in cosmetics and skincare products for its mild exfoliating properties.
L-(−)-malic acid can be found in chemical peels, facial masks, and skincare formulations designed to improve skin texture and appearance.

Pharmaceuticals:
In the pharmaceutical industry, L-(−)-malic acid can be used as an excipient in tablet formulations and as a component in certain medications.
L-(−)-malic acid may also be used as an ingredient in effervescent tablets.

Agriculture:
L-(−)-malic acid is sometimes used in agriculture to adjust soil pH levels, especially in orchards and vineyards.
Proper pH levels in the soil can improve nutrient availability to plants and enhance crop growth.

Biotechnology and Research:
In research and biotechnology, L-(−)-malic acid is used in various biochemical and molecular biology applications.
L-(−)-malic acid can serve as a substrate in enzymatic reactions and as a buffer solution in laboratory experiments.

Industrial Cleaning:
L-(−)-malic acid is used in some industrial cleaning products as an environmentally friendly alternative to harsher chemicals for descaling and cleaning purposes.

Water Treatment:
In water treatment, L-(−)-malic acid can be employed to adjust pH levels and prevent corrosion in water distribution systems.

Oral Care Products:
Some toothpaste formulations may include malic acid for its mild abrasive and tartar-control properties.

Nutraceuticals:
L-(−)-malic acid is used in the formulation of certain nutraceutical and dietary supplement products.

Artificial Flavors and Fragrances:
In the fragrance and flavor industry, L-(−)-malic acid can be used as a component in artificial flavorings and fragrances.

Beverages:
L-(−)-malic acid is frequently used in the beverage industry to provide a crisp and tart flavor in fruit juices, fruit-flavored sodas, and energy drinks.

Carbonated Beverages:
L-(−)-malic acid is an essential component in many carbonated soft drinks, contributing to their characteristic acidity and taste.

Sports Drinks:
L-(−)-malic acid is added to sports and energy drinks to enhance their refreshing and slightly sour profile.

Flavored Waters:
Some flavored bottled waters contain L-(−)-malic acid to create a pleasing taste experience.

Fruit Juices:
L-(−)-malic acid is used to adjust the acidity and flavor profile of fruit juices, ensuring a balanced and appealing taste.

Confectionery:
L-(−)-malic acid is a key ingredient in sour candies, gummies, and fruit-flavored sweets, delivering the desired tangy sensation.

Preserves:
In the production of jams and jellies, L-(−)-malic acid helps maintain acidity levels, aiding in preservation and flavor.

Salad Dressings:
L-(−)-malic acid is used to impart tanginess to salad dressings, vinaigrettes, and marinades.

Canned Fruits and Vegetables:
L-(−)-malic acid is employed as a food preservative and pH regulator in canned fruits and vegetables.

Wine Industry:
In winemaking, L-(−)-malic acid can be added to influence acidity, and its presence or absence affects the taste and quality of wine.

Cosmetic Exfoliants:
L-(−)-malic acid is utilized in cosmetic products like exfoliating scrubs and chemical peels to remove dead skin cells and improve skin texture.

Skin Cleansers:
Some facial cleansers and toners contain L-(−)-malic acid to help balance the skin's pH.

Anti-Aging Creams:
L-(−)-malic acid can be found in anti-aging creams and serums for its potential benefits in reducing signs of aging.

Effervescent Tablets:
L-(−)-malic acid is used in effervescent tablets and powders to create the characteristic fizz when dissolved in water.

Nutraceuticals:
L-(−)-malic acid is an ingredient in some dietary supplements and nutraceutical products, often combined with other compounds for health benefits.

Soil Amendments:
In agriculture, L-(−)-malic acid can be applied as a soil amendment to adjust pH levels for optimal plant growth.

Water Treatment:
L-(−)-malic acid is used in water treatment processes to control pH and prevent corrosion in water distribution systems.

Buffer Solutions:
L-(−)-malic acid is employed as a buffer solution in biochemical and laboratory applications to maintain pH stability.

Industrial Cleaning:
Some industrial cleaning products use L-(−)-malic acid as a safe and effective descaling agent.

Dentistry:
L-(−)-malic acid can be found in certain toothpaste formulations for its mild abrasive properties and tartar control.

Dietary Acidifier:
In pet food, L-(−)-malic acid may be used as a dietary acidifier to regulate urinary pH levels in certain animals.

Artificial Flavors:
L-(−)-malic acid is used as an artificial flavoring agent in various food and beverage products.

Flavor Enhancer:
L-(−)-malic acid enhances the overall flavor profile of processed foods, making them more appealing to consumers.

Preservation:
L-(−)-malic acid contributes to the preservation of packaged and canned foods by controlling pH and acidity.

Biotechnology:
In biotechnology and research, L-(−)-malic acid serves as a versatile compound in various biochemical experiments and assays.

Fruit-Based Products:
L-(−)-malic acid is used to enhance the flavor of fruit-based products like fruit syrups, fruit sauces, and fruit fillings for pastries.

Canned Vegetables:
L-(−)-malic acid helps maintain the quality and taste of canned vegetables, such as green beans and peas, by regulating acidity.

Frozen Desserts:
L-(−)-malic acid can be found in frozen desserts like sorbets and sherbets, adding a pleasant tartness.

Baking:
In baking, L-(−)-malic acid may be used as a leavening agent, contributing to the rise and texture of baked goods.

Chewing Gum:
Some chewing gum formulations include malic acid for its sour and fruity taste.

Processed Meats:
L-(−)-malic acid is used to modify the taste and texture of processed meats like sausages and deli meats.

Flavored Alcoholic Beverages:
L-(−)-malic acid is added to flavored alcoholic beverages, such as wine coolers and flavored vodkas.

Fruit-Based Snacks:
In fruit snacks and fruit leathers, malic acid enhances the natural fruit flavors.

Cider Production:
In cider-making, L-(−)-malic acid is a naturally occurring acid in apple juice, and its concentration influences cider taste.

Sour Mixes:
L-(−)-malic acid is a component in sour cocktail mixes, contributing to the desired tangy flavor.

Fruit Pectins:
L-(−)-malic acid can be added to fruit pectin preparations to help set jams and jellies.

Cheese Manufacturing:
In cheese production, malic acid may be used to control pH levels during fermentation.

Carbonated Water:
L-(−)-malic acid can be used to carbonate water, creating sparkling water or soda water.

pH Control in Brewing:
In brewing, L-(−)-malic acid can be added to adjust pH levels during the brewing process.

pH Control in Food Processing:
L-(−)-malic acid is employed in various food processing applications to control and maintain pH levels.

Fruit Flavoring:
L-(−)-malic acid is used as a fruit flavor enhancer in candies, gels, and fruit-flavored toppings.

Energy Gels:
L-(−)-malic acid is an ingredient in energy gels and chews for athletes, providing both flavor and a quick source of energy.

Gummy Vitamins:
Some gummy vitamin supplements contain malic acid for taste and texture improvement.

Personal Care Products:
L-(−)-malic acid can be found in personal care products like shampoos and conditioners as a pH regulator.

Biodegradable Plastics:
L-(−)-malic acid is being explored as a potential component in the development of biodegradable plastics.



DESCRIPTION


L-(−)-Malic acid, also known simply as malic acid, is a naturally occurring organic compound with the chemical formula C4H6O5.
L-(−)-malic acid is a dicarboxylic acid, meaning it has two carboxylic acid functional groups (-COOH) in its structure.
Malic acid is chiral and exists in two enantiomeric forms: L-malic acid and D-malic acid.
The "L" designation refers to its specific optical rotation.

L-(−)-malic acid is the naturally occurring form found in various fruits, including apples, grapes, and cherries.
L-(−)-malic acid contributes to the tart or sour taste of these fruits.
L-(−)-malic acid is also commonly used in the food and beverage industry as an acidulant to impart a sour or acidic taste to products like candies, beverages, and fruit-flavored snacks.
Additionally, L-malic acid is used as a food additive for its acidity-regulating and flavor-enhancing properties.

L-(−)-malic acid is a naturally occurring organic compound found in various fruits and vegetables.
L-(−)-malic acid is a dicarboxylic acid, which means it contains two carboxylic acid functional groups (-COOH) in its chemical structure.

L-(−)-malic acid is optically active, with a specific optical rotation that characterizes its enantiomeric form.
It exists in two enantiomeric forms: L-malic acid (the naturally occurring form) and D-malic acid.
The "L" designation indicates the stereochemistry of its optical activity.

L-malic acid is responsible for the tart or sour taste in fruits like apples, grapes, and cherries.
In addition to its presence in fruits, it can also be found in some vegetables, such as tomatoes and carrots.
L-(−)-malic acid plays a crucial role in the Krebs cycle (citric acid cycle) in cellular respiration, where it is involved in energy production.

L-(−)-malic acid is water-soluble and has a molecular formula of C4H6O5.
L-(−)-malic acid is commonly used in the food and beverage industry as an acidulant to impart a sour taste to products.

L-(−)-malic acid is considered safe for consumption and is often used in food and beverage products as an acidity regulator.
It is utilized in the production of sour candies, fruit-flavored beverages, and fruit-flavored snacks.
L-(−)-malic acid is used as a food additive to enhance the flavor of various processed foods.
L-(−)-malic acid is known for its ability to enhance the overall taste profile of products by providing a balanced sourness.

In winemaking, L-malic acid can be naturally present in grapes and is often monitored and controlled during fermentation to influence the wine's acidity.
L-(−)-malic acid can also be used as an ingredient in the formulation of some pharmaceuticals and dietary supplements.
In the cosmetics industry, L-(−)-malic acid is used in skincare products for its mild exfoliating properties.

L-(−)-malic acid is a versatile compound that contributes to the preservation and flavor enhancement of many food and beverage items.
L-(−)-malic acid has a role in buffering pH levels in biological systems and maintaining cellular functions.
L-(−)-malic acid has a crisp and refreshing taste, making it an ideal component in various beverages and confectionery.

L-(−)-malic acid is considered safe for consumption, and the human body metabolizes it without harmful effects.
L-(−)-malic acid can be synthesized from citric acid or obtained through extraction from natural sources.
Its sour taste makes it a popular choice for creating sour candies and sour-flavored products.

In the field of agriculture, L-(−)-malic acid is sometimes used to adjust the pH of soil in order to optimize plant growth.
L-(−)-malic acid is a multifaceted compound with applications spanning from food and beverages to agriculture and biochemistry.



PROPERTIES


Chemical Formula: C4H6O5
Molar Mass: Approximately 134.09 grams/mol
Chemical Structure: Malic acid is a dicarboxylic acid with two carboxylic acid functional groups (-COOH) in its structure. It has both cis and trans isomers.


Physical Properties:

Physical State: Malic acid is typically found as a white, crystalline powder or granules.
Melting Point: The melting point of malic acid is approximately 130-132°C (266-270°F).
Solubility: It is highly soluble in water, and its solubility increases with temperature.
Density: The density of malic acid varies with temperature and concentration but is typically around 1.59 g/cm³.
Odor and Taste: Malic acid has a sour or tart taste, and it is odorless.
Hygroscopicity: It exhibits hygroscopic properties, meaning it can absorb moisture from the air.
Optical Activity: Malic acid exists in two enantiomeric forms: L-malic acid and D-malic acid. L-malic acid is the naturally occurring form and is optically active.


Chemical Properties:

Acidity: Malic acid is a weak organic acid and can act as a proton donor in aqueous solutions.
pKa Values: Malic acid has two dissociation constants (pKa values) for its carboxylic acid groups: pKa1 ≈ 3.40 and pKa2 ≈ 5.20.
Buffering Capacity: Malic acid can function as a buffer, helping to stabilize pH in various solutions.
Reactivity: It can react with certain metals, such as calcium and magnesium, forming soluble complexes.
Chirality: Malic acid is chiral and can exist in both the D and L forms, with L-malic acid being the biologically relevant form.



FIRST AID


Inhalation:

Move to Fresh Air:
If malic acid dust or vapors are inhaled and respiratory discomfort occurs, immediately move the affected person to an area with fresh air.

Assist Breathing:
If breathing difficulties persist or the person is not breathing, administer artificial respiration if trained, and seek immediate medical attention.

Keep Calm:
Encourage the affected person to stay calm and avoid panic.


Skin Contact:

Remove Contaminated Clothing:
If malic acid comes into contact with the skin, promptly remove contaminated clothing, including shoes and socks, to prevent further contact.

Rinse with Water:
Wash the affected skin gently but thoroughly with copious amounts of running water for at least 15 minutes to remove any residual malic acid.

Seek Medical Attention:
If skin irritation, redness, or chemical burns develop, seek medical advice promptly.

Wash Clothing:
Wash any contaminated clothing before reuse.


Eye Contact:

Rinse Eyes:
If malic acid splashes into the eyes, immediately rinse the affected eye(s) gently but thoroughly with lukewarm, clean water for at least 15 minutes. Use an eyewash station if available.

Hold Eyelids Open:
Hold the eyelids open while rinsing to ensure thorough washing of the eye.

Seek Medical Attention:
If eye irritation or pain persists or if there are signs of eye injury, seek immediate medical attention.

Do Not Rub Eyes:
Avoid rubbing the eyes, as it may exacerbate irritation and cause further damage.


Ingestion:

Do Not Induce Vomiting:
If malic acid is ingested accidentally, do not induce vomiting unless advised to do so by a medical professional.

Rinse Mouth:
Rinse the mouth thoroughly with water to remove any residual malic acid.

Seek Immediate Medical Attention:
Contact a poison control center or seek immediate medical attention, especially if a large quantity has been ingested.

Have Information Available:
Have the product label or container information available to provide to medical personnel.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When working with malic acid in its solid or liquid form, wear appropriate personal protective equipment (PPE), including safety goggles or a face shield, chemical-resistant gloves, and a lab coat or protective clothing.
Use respiratory protection, such as a dust mask, if handling malic acid powder in an environment with dust concentrations above recommended exposure limits.

Ventilation:
Ensure adequate ventilation in the workspace to prevent the buildup of malic acid dust or vapors.
Use local exhaust ventilation or work in well-ventilated areas.
If ventilation is insufficient, wear a NIOSH-approved respiratory protection device suitable for the specific conditions.

Avoid Contact:
Minimize skin and eye contact with malic acid. In case of accidental contact, follow the first aid measures provided earlier.

Prevent Inhalation:
Avoid inhaling malic acid dust or vapors.
Use appropriate respiratory protection when necessary.

Avoid Ingestion:
Do not consume food, beverages, or tobacco products in areas where malic acid is being handled, and always wash hands thoroughly after handling the substance.

Equipment and Tools:
Use dedicated equipment and tools for handling malic acid to prevent cross-contamination.
Clean equipment after use.


Storage:

Container:
Store malic acid in tightly sealed containers made of compatible materials, such as plastic, glass, or stainless steel.
Ensure that containers are labeled with appropriate hazard information.

Temperature:
Keep malic acid in a cool, dry place away from heat sources, direct sunlight, and open flames.
Store at a temperature below its melting point (approximately 130-132°C or 266-270°F).

Separation:
Store malic acid away from incompatible materials, such as strong bases, strong acids, and strong oxidizers, to prevent reactions or contamination.

Moisture Control:
Prevent exposure to excessive moisture, as malic acid can be hygroscopic and may absorb water from the atmosphere.
Use desiccants or moisture-absorbing materials if needed.

Childproof Storage:
Ensure that malic acid is stored out of reach of children and unauthorized personnel.

Ventilation:
If storing large quantities of malic acid, consider storing it in a well-ventilated area or in a storage cabinet with proper ventilation.

Separation from Food Products:
Store malic acid away from food and food ingredients to prevent accidental contamination.

Chemical Compatibility:
Be aware of the chemical compatibility of the storage containers and materials.
Ensure they are resistant to malic acid.


Spill and Leak Response:

Containment:
In the event of a spill, contain the spill by creating a barrier using appropriate absorbent materials, such as vermiculite, sand, or absorbent pads.

Cleaning:
Carefully clean up the spill, avoiding direct contact.
Wear appropriate PPE during cleanup.

Disposal:
Dispose of contaminated materials and residues in accordance with local regulations and guidelines for hazardous waste disposal.



SYNONYMS


Hydroxysuccinic acid
Hydroxybutanedioic acid
2-Hydroxybutanedioic acid
2-Hydroxybutanedioate
DL-hydroxysuccinic acid
DL-malate
Apple acid
Alpha-hydroxysuccinic acid
2-Carboxy-2-hydroxybutanedioic acid
E296 (Food additive code)
L(−)-Hydroxysuccinic acid
Apple juice acid
L-malic acid
D-malic acid
D-hydroxysuccinic acid
L-hydroxysuccinic acid
DL-alpha-hydroxysuccinic acid
DL-malate
Hydroxybutanedioic acid (DL-form)
Hydroxysuccinate
2-Hydroxybutanedioate
Hydroxybutanedioate
Dihydroxysuccinic acid
2-Carboxy-2-hydroxybutanedioate
2-Hydroxybutanedioic acid (DL-form)
L(+)-LACTIC ACID
DESCRIPTION:
L(+)-Lactic Acid is an organic acid.
L(+)-Lactic Acid has the molecular formula CH3CH(OH)COOH.
L(+)-Lactic Acid is white in the solid state and L(+)-Lactic Acid is miscible with water.
When in the dissolved state, it forms a colorless solution.
Production includes both artificial synthesis as well as natural sources.

CAS Number 50-21-5
EC Number 200-018-0
Empirical Formula (Hill Notation):C3H6O3


SYNONYM(S) OF L(+)-LACTIC ACID:
(S)-2-Hydroxypropionic acid, Sarcolactic acid,2 Hydroxypropanoic Acid,2 Hydroxypropionic Acid,2-Hydroxypropanoic Acid,2-Hydroxypropionic Acid,Ammonium Lactate,D Lactic Acid,D-Lactic Acid,L Lactic Acid,L-Lactic Acid,Lactate,Lactate, Ammonium,Lactic AcidPropanoic Acid, 2-Hydroxy-, (2R)-,Propanoic Acid, 2-Hydroxy-, (2S)-,Sarcolactic Acid,L-Lactic acid,79-33-4,L-(+)-Lactic acid,(S)-Lactic acid,(S)-2-Hydroxypropanoic acid,Sarcolactic acid,(2S)-2-hydroxypropanoic acid,(+)-Lactic acid,(S)-2-Hydroxypropionic acid,Paralactic acid,(S)-(+)-Lactic acid,L(+)-LACTIC ACID,Tisulac,Lactic acid, L-,PURAC,Paramilchsaeure,Fleischmilchsaeure,(S)-Milchsaeure,(S)-lactate,Acidum sarcolacticum,Sarcolacticum acidum,L-lactate,Propanoic acid, 2-hydroxy-, (2S)-,Pleo sanvis,PH 90,(S)-2-Hydroxypropionsaeure,L-(+)-alpha-Hydroxypropionic acid,L-Milchsaeure,UNII-F9S9FFU82N,PROPANOIC ACID, 2-HYDROXY-, (S)-,EINECS 201-196-2,F9S9FFU82N,CHEBI:422,L(+)-2-Hydroxypropionsaeure,BRN 1720251,L-Lactic Acid, 90%,DEXTROROTATORY LACTIC ACID,EC 201-196-2,4-03-00-00633 (Beilstein Handbook Reference),l-milchsaure,(+)-Lactate,Sodium (S)-lactate,(S)-LACTIC ACID (EP MONOGRAPH),(S)-LACTIC ACID [EP MONOGRAPH],PLLA,S-Lactic acid; (S)-2-hydroxypropanoic acid,1-Hydroxyethane 1-carboxylic acid,L-lacticacid,Lactisan Winter,Pleo Sanuvis,MFCD00064266,(alpha)-Lactate,L-Iactic acid,L Lactic Acid,a-Hydroxypropanoate,a-Hydroxypropionate,26811-96-1,2OP,ClO2-C Activator,nchembio867-comp9,(alpha)-Lactic acid,alpha-Hydroxypropanoate,alpha-Hydroxypropionate,L-2-Hydroxypropanoate,a-Hydroxypropanoic acid,a-Hydroxypropionic acid,L-(+) Lactic Acid,(S)-2-Hydroxypropanoate,(S)-2-Hydroxypropionate,1-Hydroxyethanecarboxylate,L-Lactic acid, anhydrous,L-2-Hydroxypropanoic acid,bmse000208,bmse000818,Bmse000979,D-Lactic Acid (90%),(S)-2-hydroxy-Propanoate,(?)-LACTATE,L-LACTIC ACID [MI],L-LACTIC ACID (+),L-LACTIC ACID [JAN],L-(+)-Lactic acid solution,1-Hydroxyethane 1-carboxylate,LACTIC ACID, L-(II),(S)-2-hydroxy-Propanoic acid,(S)-2-hydroxy-propionic acid,CHEMBL330546,GTPL2932,L- LACTIC ACID (+),(S)-(+)-2-Hydroxypropanoate,L-(+)-Lactic acid, 80%,(S)(+)2 hydroxypropionic acid,DTXSID6034689,LACTIC ACID, L- [II],(s)(+)-2 hydroxypropionic acid,SARCOLACTIC ACID [WHO-DD],L-(+)-Lactic acid 95% liquid,80% (w/w) Lactic Acid Solution,L-(+)-Lactic acid solution, 1M,L-(+)-Lactic acid, >=98%,SARCOLACTICUM ACIDUM [HPUS],(S)-(+)-2-Hydroxypropanoic acid,2-Hydroxypropanoic acid, (S)- #,HY-Y0479,s6250,AKOS025146504,DB14475,L-Lactic acid, crystalline, 98.0%+,L-(+)-Lactic acid, analytical,standard,CS-0015266,L0165,NS00006010,EN300-91905,C00186,D71144,G64463,L-0990,L-1000,L-(+)-Lactic acid, BioXtra, >=98% (titration),L-(+)-Lactic acid, Vetec(TM) reagent grade, 86%,Q27080955,5E39D33D-2F71-4C24-BC7A-5E6F27E4CF83,L+Lactic Acid, Free Acid (S)-2-Hydroxypropionic acid, Sarcolactic acid,2-HYDROXYPROPIONIC ACID , L-(+)-Lactic acid , (S)-2-Hydroxypropanoic acid,(S)-2-Hydroxypropanoic acid; L-(+)-Lactic acid; Propanoic acid, 2-hydroxy-, (S)-; Lactic acid, L-; Espiritin; (S)-2-Hydroxypropionic acid; (+)-Lactic acid; (S)-Lactic acid; (S)-(+)-Lactic acid; Paralactic acid; Sarcolactic acid; Tisulac; PH 90; Propanoic acid, 2-hydroxy-, (2S)-; PURAC; lactate



(S)-lactic acid is an optically active form of lactic acid having (S)-configuration.
L(+)-Lactic Acid has a role as an Escherichia coli metabolite and a human metabolite.
L(+)-Lactic Acid is a 2-hydroxypropanoic acid and a (2S)-2-hydroxy monocarboxylic acid.

L(+)-Lactic Acid is a conjugate acid of a (S)-lactate.
L(+)-Lactic Acid is an enantiomer of a (R)-lactic acid.


L-Lactic acid is a metabolite found in or produced by Escherichia coli (strain K12, MG1655).


L-Lactic acid is a natural product found in Arabidopsis thaliana, Homo sapiens, and other organisms with data available.




Lactic acid is an alpha-hydroxy acid (AHA) due to the presence of a hydroxyl group adjacent to the carboxyl group.
L(+)-Lactic Acid is used as a synthetic intermediate in many organic synthesis industries and in various biochemical industries.
The conjugate base of lactic acid is called lactate (or the lactate anion).
The name of the derived acyl group is lactoyl.

In solution, it can ionize by a loss of a proton to produce the lactate ion CH
3CH(OH)CO−

2. Compared to acetic acid, its pKa is 1 unit less, meaning lactic acid is ten times more acidic than acetic acid.
This higher acidity is the consequence of the intramolecular hydrogen bonding between the α-hydroxyl and the carboxylate group.
Lactic acid is chiral, consisting of two enantiomers.

One is known as l-lactic acid, (S)-lactic acid, or (+)-lactic acid, and the other, its mirror image, is d-lactic acid, (R)-lactic acid, or (−)-lactic acid.
A mixture of the two in equal amounts is called dl-lactic acid, or racemic lactic acid.

Lactic acid is hygroscopic. dl-Lactic acid is miscible with water and with ethanol above its melting point, which is about 16 to 18 °C (61 to 64 °F). d-Lactic acid and l-lactic acid have a higher melting point.

Lactic acid produced by fermentation of milk is often racemic, although certain species of bacteria produce solely d-lactic acid.[6]
On the other hand, lactic acid produced by anaerobic respiration in animal muscles has the (l) enantiomer and is sometimes called "sarcolactic" acid, from the Greek sarx, meaning "flesh".

In animals, l-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation during normal metabolism and exercise.[7]
It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal, which is governed by a number of factors, including monocarboxylate transporters, concentration and isoform of LDH, and oxidative capacity of tissues.[7]

The concentration of blood lactate is usually 1–2 mMTooltip millimolar at rest, but can rise to over 20 mM during intense exertion and as high as 25 mM afterward.
In addition to other biological roles, l-lactic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 1 (HCA1), which is a Gi/o-coupled G protein-coupled receptor (GPCR).
In industry, lactic acid fermentation is performed by lactic acid bacteria, which convert simple carbohydrates such as glucose, sucrose, or galactose to lactic acid.


These bacteria can also grow in the mouth; the acid they produce is responsible for the tooth decay known as cavities.
In medicine, lactate is one of the main components of lactated Ringer's solution and Hartmann's solution.

These intravenous fluids consist of sodium and potassium cations along with lactate and chloride anions in solution with distilled water, generally in concentrations isotonic with human blood.
It is most commonly used for fluid resuscitation after blood loss due to trauma, surgery, or burns.

HISTORY OF L(+)-LACTIC ACID:

Swedish chemist Carl Wilhelm Scheele was the first person to isolate lactic acid in 1780 from sour milk.[16]
The name reflects the lact- combining form derived from the Latin word lac, meaning "milk".
In 1808, Jöns Jacob Berzelius discovered that lactic acid (actually l-lactate) also is produced in muscles during exertion.[17]

Its structure was established by Johannes Wislicenus in 1873.
In 1856, the role of Lactobacillus in the synthesis of lactic acid was discovered by Louis Pasteur.
This pathway was used commercially by the German pharmacy Boehringer Ingelheim in 1895.

In 2006, global production of lactic acid reached 275,000 tonnes with an average annual growth of 10%.[18]


PRODUCTION OF L(+)-LACTIC ACID:
Lactic acid is produced industrially by bacterial fermentation of carbohydrates, or by chemical synthesis from acetaldehyde.[19]
As of 2009, lactic acid was produced predominantly (70–90%)[20] by fermentation.
Production of racemic lactic acid consisting of a 1:1 mixture of d and l stereoisomers, or of mixtures with up to 99.9% l-lactic acid, is possible by microbial fermentation.

Industrial scale production of d-lactic acid by fermentation is possible, but much more challenging.

Fermentative production:
Fermented milk products are obtained industrially by fermentation of milk or whey by Lactobacillus bacteria: Lactobacillus acidophilus, Lacticaseibacillus casei (Lactobacillus casei), Lactobacillus delbrueckii subsp. bulgaricus (Lactobacillus bulgaricus), Lactobacillus helveticus, Lactococcus lactis , Bacillus amyloliquefaciens, and Streptococcus salivarius subsp. thermophilus (Streptococcus thermophilus).

As a starting material for industrial production of lactic acid, almost any carbohydrate source containing C5 (Pentose sugar) and C6 (Hexose sugar) can be used.
Pure sucrose, glucose from starch, raw sugar, and beet juice are frequently used.[21]
Lactic acid producing bacteria can be divided in two classes: homofermentative bacteria like Lactobacillus casei and Lactococcus lactis, producing two moles of lactate from one mole of glucose, and heterofermentative species producing one mole of lactate from one mole of glucose as well as carbon dioxide and acetic acid/ethanol.[22]

Chemical production:
Racemic lactic acid is synthesized industrially by reacting acetaldehyde with hydrogen cyanide and hydrolysing the resultant lactonitrile.
When hydrolysis is performed by hydrochloric acid, ammonium chloride forms as a by-product; the Japanese company Musashino is one of the last big manufacturers of lactic acid by this route.
Synthesis of both racemic and enantiopure lactic acids is also possible from other starting materials (vinyl acetate, glycerol, etc.) by application of catalytic procedures.[24]

Biology:
Molecular biology
l-Lactic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 1 (HCA1), a Gi/o-coupled G protein-coupled receptor (GPCR).
Metabolism and exercise
During power exercises such as sprinting, when the rate of demand for energy is high, glucose is broken down and oxidized to pyruvate, and lactate is then produced from the pyruvate faster than the body can process it, causing lactate concentrations to rise.

The production of lactate is beneficial for NAD+ regeneration (pyruvate is reduced to lactate while NADH is oxidized to NAD+), which is used up in oxidation of glyceraldehyde 3-phosphate during production of pyruvate from glucose, and this ensures that energy production is maintained and exercise can continue.

During intense exercise, the respiratory chain cannot keep up with the amount of hydrogen ions that join to form NADH, and cannot regenerate NAD+ quickly enough, so pyruvate is converted to lactate to allow energy production by glycolysis to continue.[25]

The resulting lactate can be used in two ways:
Oxidation back to pyruvate by well-oxygenated muscle cells, heart cells, and brain cells
Pyruvate is then directly used to fuel the Krebs cycle
Conversion to glucose via gluconeogenesis in the liver and release back into circulation by means of the Cori cycle[26]

If blood glucose concentrations are high, the glucose can be used to build up the liver's glycogen stores.
Lactate is continually formed at rest and during all exercise intensities.

Lactate serves as a metabolic fuel being produced and oxidatively disposed in resting and exercising muscle and other tissues.[25]
Some sources of excess lactate production are metabolism in red blood cells, which lack mitochondria that perform aerobic respiration, and limitations in the rates of enzyme activity in muscle fibers during intense exertion.[26]

Lactic acidosis is a physiological condition characterized by accumulation of lactate (especially l-lactate), with formation of an excessively high proton concentration [H+] and correspondingly low pH in the tissues, a form of metabolic acidosis.[25]
The first stage in metabolizing glucose is glycolysis, the conversion of glucose to pyruvate− and H+:
C6H12O6 + 2 NAD+ + 2 ADP3− + 2 HPO2−4 → 2 CH3COCO−2 + 2 H+ + 2 NADH + 2 ATP4− + 2 H2O

When sufficient oxygen is present for aerobic respiration, the pyruvate is oxidized to CO2 and water by the Krebs cycle, in which oxidative phosphorylation generates ATP for use in powering the cell.
When insufficient oxygen is present, or when there is insufficient capacity for pyruvate oxidation to keep up with rapid pyruvate production during intense exertion, the pyruvate is converted to lactate− by lactate dehydrogenase), a process that absorbs these protons:[27]
2 CH3COCO−2 + 2 H+ + 2 NADH → 2 CH3CH(OH)CO−2 + 2 NAD+
The combined effect is:
C6H12O6 + 2 ADP3− + 2HPO2−4 → 2 CH3CH(OH)CO−2 + 2 ATP4− + 2 H2O
The production of lactate from glucose (glucose → 2 lactate− + 2 H+), when viewed in isolation, releases two H+. The H+ are absorbed in the production of ATP, but H+ is subsequently released during hydrolysis of ATP:
ATP4− + H2O → ADP3− + HPO2−4 + H+
Once the production and use of ATP is included, the overall reaction is
C6H12O6 → 2 CH3CH(OH)CO−2 + 2 H+
The resulting increase in acidity persists until the excess lactose and protons are converted back to pyruvate, and then to glucose for later use, or to CO2 and water for the production of ATP.[25]


Neural tissue energy source
Although glucose is usually assumed to be the main energy source for living tissues, there is evidence that lactate, in preference to glucose, is preferentially metabolized by neurons in the brains of several mammalian species that include mice, rats, and humans.
According to the lactate-shuttle hypothesis, glial cells are responsible for transforming glucose into lactate, and for providing lactate to the neurons.

Because of this local metabolic activity of glial cells, the extracellular fluid immediately surrounding neurons strongly differs in composition from the blood or cerebrospinal fluid, being much richer with lactate, as was found in microdialysis studies.[28]

Brain development metabolism:
Some evidence suggests that lactate is important at early stages of development for brain metabolism in prenatal and early postnatal subjects, with lactate at these stages having higher concentrations in body liquids, and being utilized by the brain preferentially over glucose.[28]

It was also hypothesized that lactate may exert a strong action over GABAergic networks in the developing brain, making them more inhibitory than it was previously assumed,[32] acting either through better support of metabolites,[28] or alterations in base intracellular pH levels,[33][34] or both.

Studies of brain slices of mice show that β-hydroxybutyrate, lactate, and pyruvate act as oxidative energy substrates, causing an increase in the NAD(P)H oxidation phase, that glucose was insufficient as an energy carrier during intense synaptic activity and, finally, that lactate can be an efficient energy substrate capable of sustaining and enhancing brain aerobic energy metabolism in vitro.[36]

The study "provides novel data on biphasic NAD(P)H fluorescence transients, an important physiological response to neural activation that has been reproduced in many studies and that is believed to originate predominantly from activity-induced concentration changes to the cellular NADH pools."
Lactate can also serve as an important source of energy for other organs, including the heart and liver.
During physical activity, up to 60% of the heart muscle's energy turnover rate derives from lactate oxidation.



USES OF L(+)-LACTIC ACID:
Polymer precursor[edit]
Two molecules of lactic acid can be dehydrated to the lactone lactide.
In the presence of catalysts lactide polymerize to either atactic or syndiotactic polylactide (PLA), which are biodegradable polyesters.
PLA is an example of a plastic that is not derived from petrochemicals.


Pharmaceutical and cosmetic applications:
Lactic acid is also employed in pharmaceutical technology to produce water-soluble lactates from otherwise-insoluble active ingredients.
It finds further use in topical preparations and cosmetics to adjust acidity and for its disinfectant and keratolytic properties.
Lactic acid containing bacteria have shown promise in reducing oxaluria with its descaling properties on calcium compounds.

Foods:
Fermented food:
Lactic acid is found primarily in sour milk products, such as kumis, laban, yogurt, kefir, and some cottage cheeses.
The casein in fermented milk is coagulated (curdled) by lactic acid.
Lactic acid is also responsible for the sour flavor of sourdough bread.

In lists of nutritional information lactic acid might be included under the term "carbohydrate" (or "carbohydrate by difference") because this often includes everything other than water, protein, fat, ash, and ethanol.

If this is the case then the calculated food energy may use the standard 4 kilocalories (17 kJ) per gram that is often used for all carbohydrates.
But in some cases lactic acid is ignored in the calculation.
The energy density of lactic acid is 362 kilocalories (1,510 kJ) per 100 g.

Some beers (sour beer) purposely contain lactic acid, one such type being Belgian lambics.
Most commonly, this is produced naturally by various strains of bacteria.
These bacteria ferment sugars into acids, unlike the yeast that ferment sugar into ethanol.

After cooling the wort, yeast and bacteria are allowed to "fall" into the open fermenters.
Brewers of more common beer styles would ensure that no such bacteria are allowed to enter the fermenter.
Other sour styles of beer include Berliner weisse, Flanders red and American wild ale.


In winemaking, a bacterial process, natural or controlled, is often used to convert the naturally present malic acid to lactic acid, to reduce the sharpness and for other flavor-related reasons.
This malolactic fermentation is undertaken by lactic acid bacteria.
While not normally found in significant quantities in fruit, lactic acid is the primary organic acid in akebia fruit, making up 2.12% of the juice.

Separately added
As a food additive it is approved for use in the EU,[47] United States[48] and Australia and New Zealand;[49] it is listed by its INS number 270 or as E number E270.

Lactic acid is used as a food preservative, curing agent, and flavoring agent.
It is an ingredient in processed foods and is used as a decontaminant during meat processing.

Lactic acid is produced commercially by fermentation of carbohydrates such as glucose, sucrose, or lactose, or by chemical synthesis.
Carbohydrate sources include corn, beets, and cane sugar


CHEMICAL AND PHYSICAL PROPERTIES OF L(+)-LACTIC ACID:
Chemical formula C3H6O3
Molar mass 90.078 g•mol−1
Melting point 18 °C (64 °F; 291 K)
Boiling point 122 °C (252 °F; 395 K) at 15 mmHg
Solubility in water Miscible[2]
Acidity (pKa) 3.86,[3] 15.1[4]
Thermochemistry
Std enthalpy of
combustion (ΔcH⦵298) 1361.9 kJ/mol, 325.5 kcal/mol, 15.1 kJ/g, 3.61 kcal/g
Molecular Weight
90.08 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3
-0.7
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
90.031694049 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
90.031694049 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
57.5Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
6
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
59.1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
1
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
Color White
Formula Weight 90.08
Density 1190 to 1250kg/mL
Quantity 25 g
Physical Form Solid
Chemical Name or Material L-Lactic Acid, Free Acid



SAFETY INFORMATION ABOUT L(+)-LACTIC ACID:
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.



L(+)-TARTARIC ACID
L(+)-Tartaric acid is a conjugate acid of a L-tartrate(1-).
L(+)-Tartaric acid is an enantiomer of a D-tartaric acid.
L-(+)-Tartaric Acid is a naturally occurring chemical compound found in berries, grapes and various wines.


CAS Number: 87-69-4
EC Number: 201-766-0
MDL number: MFCD00064207
Molecular Formula: C4H6O6 / COOH(CHOH)2COOH / H2C4H4O6



SYNONYMS:
(+)-L-Tartaric acid, (+)-Tartaric acid, 87-69-4, L-(+)-Tartaric acid, L-Tartaric acid, L(+)-Tartaric acid, tartaric acid, (2R,3R)-2,3-dihydroxysuccinic acid, (2R,3R)-2,3-dihydroxybutanedioic acid, (R,R)-Tartaric acid, Threaric acid, L-threaric acid, Dextrotartaric acid, Acidum tartaricum, Natural tartaric acid, (+)-(R,R)-Tartaric acid, (2R,3R)-(+)-Tartaric acid, Tartaric acid, L-, Rechtsweinsaeure, Kyselina vinna, (2R,3R)-Tartaric acid, (R,R)-(+)-Tartaric acid, tartrate, Succinic acid, 2,3-dihydroxy, Weinsteinsaeure, L-2,3-Dihydroxybutanedioic acid, (2R,3R)-rel-2,3-Dihydroxysuccinic acid, 1,2-Dihydroxyethane-1,2-dicarboxylic acid, EINECS 201-766-0, (+)-Weinsaeure, 133-37-9, NSC 62778, FEMA No. 3044, INS NO.334, DTXSID8023632, UNII-W4888I119H, CHEBI:15671, Kyselina 2,3-dihydroxybutandiova, AI3-06298, Lamb protein (fungal), INS-334, (+/-)-Tartaric Acid, Butanedioic acid, 2,3-dihydroxy- (2R,3R)-, (R,R)-tartrate, NSC-62778, W4888I119H, Tartaric acid (VAN), DTXCID203632, E 334, E-334, RR-tartaric acid, (+)-(2R,3R)-Tartaric acid, Tartaric acid, L-(+)-, EC 201-766-0, TARTARIC ACID (L(+)-), Tartaric acid, Weinsaeure, BAROS COMPONENT TARTARIC ACID, L-2,3-DIHYDROXYSUCCINIC ACID, MFCD00064207, C4H6O6, L-tartarate, 4J4Z8788N8, 138508-61-9, (2R,3R)-2,3-Dihydroxybernsteinsaeure, Resolvable tartaric acid, d-alpha,beta-Dihydroxysuccinic acid, TARTARIC ACID (II), TARTARIC ACID [II], 144814-09-5, Kyselina 2,3-dihydroxybutandiova [Czech], REL-(2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID, TARTARIC ACID (MART.), TARTARIC ACID [MART.], (1R,2R)-1,2-Dihydroxyethane-1,2-dicarboxylic acid, TARTARIC ACID (USP-RS), TARTARIC ACID [USP-RS], BUTANEDIOIC ACID, 2,3-DIHYDROXY-, (R-(R*,R*))-, Tartaric acid D,L, Butanedioic acid, 2,3-dihydroxy- (R-(R*,R*))-, TARTARIC ACID (EP MONOGRAPH), TARTARIC ACID [EP MONOGRAPH], Tartarate, L(+) tartaric acid, (2RS,3RS)-Tartaric acid, 2,3-dihydroxy-succinic acid, Traubensaeure, Vogesensaeure, Weinsaure, acide tartrique, acido tartarico, tartaric-acid, para-Weinsaeure, L-Threaric aci, 4ebt, NSC 148314, NSC-148314, (r,r)-tartarate, (+)-tartarate, l(+)tartaric acid, Tartaric acid; L-(+)-Tartaric acid, Tartaric acid (TN), (+-)-Tartaric acid, Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-, L-(+) tartaric acid, (2R,3R)-Tartarate, 1d5r, DL TARTARIC ACID, TARTARICUM ACIDUM, 2,3-dihydroxy-succinate, TARTARIC ACID,DL-, SCHEMBL5762, TARTARIC ACID, DL-, Tartaric acid (JP17/NF), TARTARIC ACID [FCC], TARTARIC ACID [JAN], d-a,b-Dihydroxysuccinic acid, MLS001336057, L-TARTARIC ACID [MI], TARTARIC ACID [VANDF], DL-TARTARIC ACID [MI], CCRIS 8978, L-(+)-Tartaric acid, ACS, TARTARIC ACID [WHO-DD], CHEMBL1236315, L-(+)-Tartaric acid, BioXtra, TARTARICUM ACIDUM [HPUS], UNII-4J4Z8788N8, (2R,3R)-2,3-tartaric acid, CHEBI:26849, HMS2270G22, Pharmakon1600-01300044, TARTARIC ACID, DL- [II], TARTARIC ACID, (+/-)-, TARTARIC ACID,DL- [VANDF], HY-Y0293, STR02377, TARTARIC ACID [ORANGE BOOK], EINECS 205-105-7, Tox21_300155, (2R,3R)-2,3-dihydroxysuccinicacid, NSC759609, s6233, AKOS016843282, L-(+)-Tartaric acid, >=99.5%, CS-W020107, DB09459, NSC-759609, (2R,3R)-2,3-dihydroxy-succinic acid, Butanedioic acid, 2,3-dihydroxy-; Butanedioic acid, 2,3-dihydroxy-, (R-(R*,R*))-, CAS-87-69-4, L-(+)-Tartaric acid, AR, >=99%, TARTARIC ACID COMPONENT OF BAROS, (R*,R*)-2,3-dihydroxybutanedioic acid, NCGC00247911-01, NCGC00254043-01, BP-31012, SMR000112492, SBI-0207063.P001, (2R,3R)-rel-2,3-dihydroxybutanedioic acid, NS00074184, T0025, EN300-72271, (R*,R*)-(+-)-2,3-dihydroxybutanedioic acid, C00898, D00103, D70248, L-(+)-Tartaric acid, >=99.7%, FCC, FG, L-(+)-Tartaric acid, ACS reagent, >=99.5%, L-(+)-Tartaric acid, BioUltra, >=99.5% (T), J-500964, TARTARIC ACID, L-TARTARIC ACID, TARTRATE, (2R,3R)-2,3-DIHYDROXYSUCCINIC ACID, Tartaric, lev, 2,3-Dihydroxysuccinic acid, l-tartaric, 2,3-DIHYDROXYBUTANEDIOIC ACID, levo, [R-(R*,R*)]-2,3-Dihydroxybutanedioic acid, L-2,3-Dihydroxybutanedioic acid, ordinary tartaric acid, natural tartaric acid, d-tartaric acid, (+)-tartaric acid, dextrotartaric acid, d-α,β-dihydroxysuccinic acid, Weinsure, Weinsteinsure, (2R,3R)-(+)-Tartaric acid, L-Threaric acid, L-2,3-Dihydroxybutanedioic acid, (2R,3R)-2,3-Dihydroxysuccinic acid, J-520420, L-(+)-Tartaric acid, ReagentPlus(R), >=99.5%, L-(+)-Tartaric acid, SAJ first grade, >=99.5%, L-(+)-Tartaric acid, tested according to Ph.Eur., Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-(+-)-, L-(+)-Tartaric acid, JIS special grade, >=99.5%, L-(+)-Tartaric acid, natural, >=99.7%, FCC, FG, L-(+)-Tartaric acid, p.a., ACS reagent, 99.0%, L-(+)-Tartaric acid, Vetec(TM) reagent grade, 99%, Q18226455, F8880-9012, Z1147451717, Butanedioic acid, 2,3-dihydroxy-, (theta,theta)-(+-)-, 000189E3-11D0-4B0A-8C7B-31E02A48A51F, L-(+)-Tartaric acid, puriss. p.a., ACS reagent, >=99.5%, L-(+)-Tartaric acid, certified reference material, TraceCERT(R), Tartaric acid, United States Pharmacopeia (USP) Reference Standard, L-(+)-Tartaric acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.5%, L-(+)-Tartaric acid, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.5%, Tartaric Acid, Pharmaceutical Secondary Standard; Certified Reference Material, 132517-61-4, 2,3-Dihydroxybutanedioic acid, l-tartaric acid, l-+-tartaric acid, l +-tartaric acid, 2r,3r-2,3-dihydroxysuccinic acid, tartaric acid, 2r,3r-2,3-dihydroxybutanedioic acid, r,r-tartaric acid, #NAME?, dextrotartaric acid, l-threaric acid, L-Tartaric acid, L-2,3-dihydroxybutanedioic acid, L-2,3-dihydroxysuccinic acid



L(+)-Tartaric acid is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 to < 100 000 tonnes per annum.
L(+)-Tartaric acid is a tetraric acid that is butanedioic acid substituted by hydroxy groups at positions 2 and 3.


L(+)-Tartaric acid is a conjugate acid of a L-tartrate(1-).
L(+)-Tartaric acid is an enantiomer of a D-tartaric acid.
L(+)-Tartaric acid belongs to the group of carboxylic acids, and is abundantly found in grapes and wine.


L(+)-Tartaric acid is colorless or translucent crystals, or a white, fine granular, crystalline powder.
L(+)-Tartaric acid is odorless, has an acid taste, and is stable in air.
L-tartaric acid is a tartaric acid.


L(+)-Tartaric acid is a conjugate acid of a L-tartrate(1-).
L(+)-Tartaric acid is an enantiomer of a D-tartaric acid.
L(+)-Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder.


L(+)-Tartaric acid is odorless, with an extremely tart taste.
L-(+)-Tartaric Acid is a naturally occurring chemical compound found in berries, grapes and various wines.
L(+)-Tartaric acid provides antioxidant properties and contributes to the sour taste within these products


L(+)-Tartaric acid is a white, crystalline organic acid, that occurs naturally in many fruits, is the primary acid component in wine grapes, is a dihydroxy dicarboxylic acid that occurs naturally in grapes.
L(+)-Tartaric acid is an orally active weak organic acid that can be isolated from grapes.


L(+)-Tartaric acid has vasodilatory and antihypertensive effects.
L(+)-Tartaric acid is soluble in water, methanol and acetone.
L(+)-Tartaric acid is incompatible with oxidizing agents, bases and reducing agents.


L(+)-Tartaric acid belongs to the class of organic compounds known as sugar acids and derivatives.
Sugar acids and derivatives are compounds containing a saccharide unit which bears a carboxylic acid group.
L(+)-Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.


Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
L(+)-Tartaric acid is a colourless or translucent crystals, or white, fine to granular, crystalline powder; odourless.
L(+)-Tartaric acid is an endogenous metabolite.


L(+)-Tartaric acid is the primary nonfermentable soluble acid in grapes and the principal acid in wine.
L(+)-Tartaric acid is abundant in nature, especially in fruits.
L(+)-Tartaric acid's primary commercial source is as a byproduct of the wine industry.


Industrial uses of L(+)-Tartaric acid include tanning, ceramics manufacture, and the production of tartrate esters for lacquers and textile printing.
L(+)-Tartaric acid is a colourless or translucent crystals, or white, fine to granular, crystalline powder; odourless.
L(+)-Tartaric acid is a naturally occurring carboxylic acid widely present in fruits like grapes, apricots, and apples.


Its significance extends beyond culinary applications, as L(+)-Tartaric acid plays a vital role in wine production, contributing to the beverage′s distinct tartness and flavor.
Throughout history, L(+)-Tartaric acid has been used in food and beverage production, but its utility has expanded into diverse scientific research areas in recent years, encompassing both in vivo and in vitro studies.


In scientific research, L(+)-Tartaric acid has been employed in various in vivo studies, where it is administered to animal models to investigate its effects on the body.
Additionally, in vitro studies utilize cell cultures and laboratory techniques to explore how L(+)-Tartaric acid impacts cellular processes.


The mechanism of action for L(+)-Tartaric acid is believed to involve its interaction with and activation of several enzymes, such as protein kinases and phosphatases.
These enzymes play pivotal roles in multiple cellular processes, including cell growth, differentiation, and apoptosis.


L(+)-Tartaric acid is a metabolite found in or produced by Escherichia coli.
L(+)-Tartaric acid is a white crystalline dicarboxylic acid found in many plants, particularly tamarinds and grapes.
In high doses, this agent acts as a muscle toxin by inhibiting the production of malic acid, which could cause paralysis and maybe death.


L(+)-Tartaric acid is a white crystalline organic acid.
L(+)-Tartaric acid occurs naturally in many plants, particularly grapes and tamarinds, and is one of the main acids found in wine.
Salts of L(+)-Tartaric acid are known as tartrates.


L(+)-Tartaric acid is a dihydroxy derivative of dicarboxylic acid.
L(+)-Tartaric acid is a muscle toxin, which works by inhibiting the production of malic acid, and in high doses causes paralysis and death.
The minimum recorded fatal dose for a human is about 12 grams.


In spite of that, L(+)-Tartaric acid is included in many foods, especially sour-tasting sweets.
As a food additive, L(+)-Tartaric acid is used as an antioxidant with E number E334, tartrates are other additives serving as antioxidants or emulsifiers.
Naturally-occurring L(+)-Tartaric acid is chiral, meaning that it has molecules that are non-superimposable on their mirror-images.


L(+)-Tartaric acid is a useful raw material in organic chemistry for the synthesis of other chiral molecules.
The naturally occurring form of the acid is L(+)-Tartaric acid or dextrotartaric acid.
The mirror-image (enantiomeric) form, levotartaric acid or D-(-)-tartaric acid, and the achiral form, mesotartaric acid, can be made artificially.


Tartarate is believed to play a role in inhibiting kidney stone formation.
Most tartarate that is consumed by humans is metabolized by bacteria in the gastrointestinal tract -- primarily in the large instestine.
Only about 15-20% of consumed tartaric acid is secreted in the urine unchanged.


L(+)-Tartaric acid has been known to winemakers for centuries.
However, the chemical process for extraction was developed in 1769 by the Swedish chemist Carl Wilhelm Scheele.
L(+)-Tartaric acid played an important role in the discovery of chemical chirality.


This property of L(+)-Tartaric acid was first observed in 1832 by Jean Baptiste Biot, who observed its ability to rotate polarized light.
Louis Pasteur continued this research in 1847 by investigating the shapes of sodium ammonium tartrate crystals, which he found to be chiral.
By manually sorting the differently shaped crystals, Pasteur was the first to produce a pure sample of levotartaric acid.



USES and APPLICATIONS of L(+)-TARTARIC ACID:
L(+)-Tartaric acid is approved in the EEA and/or Switzerland for use in biocidal products more favourable for the environment, human or animal health.
L(+)-Tartaric acid is also important in the history of chemistry because Louis Pasteur, who most people think of mainly as a biologist, used it to demonstrate molecular chirality.


Pasteur’s notebooks that described his work, however, turned up missing after his death
L(+)-Tartaric acid is widely used as acidulant in beverage,and other foods, such as soft drinks, wine, candy, bread and some colloidal sweetmeats.
L(+)-Tartaric acid is used as an additive in many foods, such as soft drinks, bakery products, and candies.


L(+)-Tartaric acid is an authorised food additive.
L(+)-Tartaric acid is used in the following products: cosmetics and personal care products, washing & cleaning products, perfumes and fragrances and fillers, putties, plasters, modelling clay.


Other release to the environment of L(+)-Tartaric acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), outdoor use and indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters).


Other release to the environment of L(+)-Tartaric acid is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


L(+)-Tartaric acid can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material).
L(+)-Tartaric acid is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


L(+)-Tartaric acid is used in the soft drink industry, confectionery products, bakery products, gelatin desserts, as an acidulant.
L(+)-Tartaric acid is used in photography, tanning, ceramics, manufacture of tartrate.
The common commercial esters are the diethyl and dibutyl derivatives used for lacquers and in textile printing.


L(+)-Tartaric acid is used pharmaceutic aid (buffering agent).
L(+)-Tartaric acid is widely utilized in pharmaceutical industries.
L(+)-Tartaric acid is used in soft drinks, confectionaries, food products, gelatin desserts and as a buffering agent.


L(+)-Tartaric acid forms a compound, TiCl2(O-i-Pr)2 with Diels-Alder catalyst and acta as a chelate agent in metal industries.
Owing to its efficient chelating property towards metal ions, L(+)-Tartaric acid is used in farming and metal industries for complexing micronutrients and for cleaning metal surfaces, respectively.


L(+)-Tartaric acid is widely used in drugs, food, and beverage industry.
L(+)-Tartaric acid is widely used as an acidulant in beverage and other foods.
L(+)-Tartaric acid is a wine industry byproduct that is used as a food additive and industrial chemical.


With its optical activity, L(+)-Tartaric acid is used as a chemical resolving agent to resolve DL-amino-butanol, an intermediate for the antitubercular drug.
And L(+)-Tartaric acid is used as a chiral pool to synthesize tartrate derivatives.


With its acidity, L(+)-Tartaric acid is used as a catalyst in the resin finishing of polyester fabric or pH value regulator in oryzanol production.
With its complexation, L(+)-Tartaric acid is used in electroplating, sulfur removal, and acid pickling.
L(+)-Tartaric acid is also used as a complexing agent, food additives screening agent or chelating agent in chemical analysis and pharmaceutical inspection, or as resist agent in dyeing.


With its reduction, L(+)-Tartaric acid is used as a reductive agent in manufacturing mirror chemically or imaging agent in photography.
L(+)-Tartaric acid is used in the following products: cosmetics and personal care products, fillers, putties, plasters, modelling clay, perfumes and fragrances and photo-chemicals.


L(+)-Tartaric acid is used in the following areas: building & construction work.
Other release to the environment of L(+)-Tartaric acid is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.


L(+)-Tartaric acid is used in the following products: adhesives and sealants, fillers, putties, plasters, modelling clay, pH regulators and water treatment products, laboratory chemicals, paper chemicals and dyes, perfumes and fragrances, photo-chemicals, cosmetics and personal care products and pharmaceuticals.


Release to the environment of L(+)-Tartaric acid can occur from industrial use: formulation of mixtures and formulation in materials.
L(+)-Tartaric acid is used for the manufacture of: food products and chemicals.
L(+)-Tartaric acid can also complex with metal ion and can be used as a cleaning agent or polishing agent of the metal surface.


L(+)-Tartaric acid is used in the following products: adhesives and sealants, pH regulators and water treatment products, metal surface treatment products, photo-chemicals, fillers, putties, plasters, modelling clay, laboratory chemicals, perfumes and fragrances, pharmaceuticals and cosmetics and personal care products.


L(+)-Tartaric acid is used for the manufacture of: food products, chemicals and mineral products (e.g. plasters, cement).
Release to the environment of L(+)-Tartaric acid can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and as processing aid.


Release to the environment of L(+)-Tartaric acid can occur from industrial use: manufacturing of the substance and as an intermediate step in further manufacturing of another substance (use of intermediates).
L(+)-Tartaric acid is a natural occurring chemical, derived from grapes and some other fruit, and it is mainly used as acidulant in the beverage industry.


L(+)-Tartaric acid can also be produced industrially, through an enantioselective synthesis process; maintaining all the characteristics of the natural occurring product, but with a more competitive level.
L(+)-Tartaric acid is an high-quality product and has a specific optical rotation [α] 25 °D of +12.0° to +13°, it is extensively used in many industries, such as food, pharmaceutical industry, chemical and building material industries.


Synthetic L(+)-Tartaric acid is made under GMP and meets the most demanding international quality standards including Food Chemicals Codex, the U.S. and the British Pharmacopoeia.
L(+)-Tartaric acid is a food additive that is widely used in a variety of food products and beverages.


L(+)-Tartaric acid is a white crystalline powder with a sour taste.
In beverages it is commonly used as an acidulant.
It is also used as a catalyst in the resin finishing of polyester fabric, as a pH value regulator in oryzanol production, and as a complexing agent, screening agent, or chelating agent in chemical analysis and pharmaceutical inspection.


L(+)-Tartaric acid is used as an acidulant in wine, food, and beverages; a raw material in the production of emulsifiers; an excipient and buffering agent in pharmaceutical products; and in other applications in plaster and effervescent antacids.
L(+)-Tartaric acid is widely utilized in pharmaceutical industries.


L(+)-Tartaric acid forms a compound, TiCl2(O-i-Pr)2 with Diels-Alder catalyst and acta as a chelate agent in metal industries.
Owing to its efficient chelating property towards metal ions, L(+)-Tartaric acid is used in farming and metal industries for complexing micronutrients and for cleaning metal surfaces, respectively.


L(+)-Tartaric acid can be used as flavorings and antioxidants in a range of foods and beverages.
L(+)-Tartaric acid can be used in laser frequency doubling and optical limiting applications.
L(+)-Tartaric acid can be used as a flavorant and antioxidant for a range of foods and beverages.


L(+)-Tartaric acid is widely utilized in pharmaceutical industries.
It is used in soft drinks, confectionaries, food products, gelatin desserts and as a buffering agent.
L(+)-Tartaric acid forms a compound, TiCl2(O-i-Pr)2 with Diels-Alder catalyst and acta as a chelate agent in metal industries.


Owing to its efficient chelating property towards metal ions, L(+)-Tartaric acid is used in farming and metal industries for complexing micronutrients and for cleaning metal surfaces, respectively.
L(+)-Tartaric acid is added to other foods to give a sour taste, and is used as an antioxidant.


L(+)-Tartaric acid is used in soft drinks, confectionaries, food products, gelatin desserts and as a buffering agent.
L(+)-Tartaric acid is used in the following areas: building & construction work, formulation of mixtures and/or re-packaging, health services and mining.


L(+)-Tartaric acid is used to generate carbon dioxide through interaction with sodium bicarbonate following oral administration.
Carbon dioxide extends the stomach and provides a negative contrast medium during double contrast radiography.


-Pharmaceutical Applications:
L(+)-Tartaric acid is used in beverages, confectionery, food products, and pharmaceutical formulations as an acidulant.
L(+)-Tartaric acid may also be used as a sequestering agent and as an antioxidant synergist.

In pharmaceutical formulations, L(+)-Tartaric acid is widely used in combination with bicarbonates, as the acid component of effervescent granules, powders, and tablets.
L(+)-Tartaric acid is also used to form molecular compounds (salts and cocrystals) with active pharmaceutical ingredients to improve physicochemical properties such as dissolution rate and solubility.



FUNCTIONAL USES OF L(+)-TARTARIC ACID:
Synergist for antioxidants, acid, sequestrant, flavouring agent



FUNCTIONS AND USAGE OF L(+)-TARTARIC ACID:
L(+)-Tartaric acid is widely used as acidulant in beverage,and other foods, such as soft drinks, wine, candy, bread and some colloidal sweetmeats.
With its optical activity, L(+)-Tartaric acid is used as chemical resolving agent to resolve DL-amino-butanol, an intermediate for antitubercular drug.

And L(+)-Tartaric acid is used as chiral pool to synthesize tartrate derivatives.
With its acidity, L(+)-Tartaric acid is used as catalyst in the resin finishing of polyester fabric or pH value regulator in oryzanol production.

With its complexation, L(+)-Tartaric acid is used in electroplating, sulfur removal and acid pickling.
L(+)-Tartaric acid is also used as complexing agent, screening agent or chelating agent in chemical analysis and pharmaceutical inspection, or as resist agent in dyeing.

With its reduction, L(+)-Tartaric acid is used as reductive agent in manufacturing mirror chemically or imaging agent in photography.
L(+)-Tartaric acid can also complex with metal ion and can be used as cleaning agent or polishing agent of metal surface.



ALTERNATIVE PARENTS OF L(+)-TARTARIC ACID:
*Short-chain hydroxy acids and derivatives
*Beta hydroxy acids and derivatives
*Monosaccharides
*Fatty acids and conjugates
*Dicarboxylic acids and derivatives
*Alpha hydroxy acids and derivatives
*Secondary alcohols
*1,2-diols
*Carboxylic acids
*Organic oxides
*Hydrocarbon derivatives
*Carbonyl compounds



SUBSTITUENTS OF L(+)-TARTARIC ACID:
*Sugar acid
*Short-chain hydroxy acid
*Beta-hydroxy acid
*Fatty acid
*Monosaccharide
*Hydroxy acid
*Dicarboxylic acid or derivatives
*Alpha-hydroxy acid
*Secondary alcohol
*1,2-diol
*Carboxylic acid
*Carboxylic acid derivative
*Organic oxide
*Hydrocarbon derivative
*Carbonyl group
*Alcohol
*Aliphatic acyclic compound



CHEMICAL PROPERTIES OF L(+)-TARTARIC ACID:
L(+)-Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder.
L(+)-Tartaric acid is odorless, with an extremely tart taste.
L(+)-Tartaric acid is a naturally occurring chemical compound found in berries, grapes and various wines.
L(+)-Tartaric acid provides antioxidant properties and contributes to the sour taste within these products.



PRODUCTION METHODS OF L(+)-TARTARIC ACID:
L(+)-Tartaric acid occurs naturally in many fruits as the free acid or in combination with calcium, magnesium, and potassium.
Commercially, L(+)-Tartaric acid is manufactured from potassium tartrate (cream of tartar), a by-product of wine making.
Potassium tartrate is treated with hydrochloric acid, followed by the addition of a calcium salt to produce insoluble calcium tartrate.
This precipitate is then removed by filtration and reacted with 70% sulfuric acid to yield tartaric acid and calcium sulfate.



BIOCHEM/PHYSIOL ACTIONS OF L(+)-TARTARIC ACID:
L(+)-Tartaric acid serves as a donor ligand for biological processes.
L(+)-Tartaric acid is used as a food additive in candies and soft drinks to impart a sour taste.



STORAGE OF L(+)-TARTARIC ACID:
The bulk material is stable and should be stored in a well-closed container in a cool, dry place.



INCOMPATIBILITIES OF L(+)-TARTARIC ACID:
L(+)-Tartaric acid is incompatible with silver and reacts with metal carbonates and bicarbonates (a property exploited in effervescent preparations).



STEREOCHEMISTRY OF L(+)-TARTARIC ACID:
Naturally occurring form of the acid is dextro tartaric acid or L(+)-Tartaric acid (obsolete name d-tartaric acid).
Because L(+)-Tartaric acid is available naturally, it is cheaper than its enantiomer and the meso isomer.

The dextro and levo prefixes are archaic terms.
Modern textbooks refer to the natural form as (2R,3R)-tartaric acid (L(+)-Tartaric acid), and its enantiomer as (2S,3S)-tartaric acid (D-(-)-tartaric acid).
The meso diastereomer is referred to as (2R,3S)-tartaric acid or (2S,3R)-tartaric acid.

Dextro and levo form monoclinic sphenoidal crystals and orthorhombic crystals.
Racemic tartaric acid forms monoclinic and triclinic crystals (space group P1).
Anhydrous meso tartaric acid form two anhydrous polymorphs: triclinic and orthorhombic.

Monohydrated meso tartaric acid crystallizes as monoclinic and triclinic polymorphys depending on the temperature at which crystallization from aqueous solution occurs.
Tartaric acid in Fehling's solution binds to copper(II) ions, preventing the formation of insoluble hydroxide salts.



PHYSICAL and CHEMICAL PROPERTIES of L(+)-TARTARIC ACID:
CAS number: 87-69-4
EC number: 201-766-0
Grade: Ph Eur, BP, ChP, JP, NF, E 334
Hill Formula: C₄H₆O₆
Chemical formula: HOOCCH(OH)CH(OH)COOH
Molar Mass: 150.09 g/mol
HS Code: 2918 12 00
Density: 1.76 g/cm³ (20 °C)
Flash point: 150 °C
Ignition temperature: 425 °C
Melting Point: 170 - 172 °C
pH value: 1.6 (100 g/l, H₂O, 25 °C)
Vapor pressure: Bulk density: 1000 kg/m³
Solubility: 1390 g/l

CAS: 87-69-4
Molecular Formula: HO2CCH(OH)CH(OH)CO2H
Molecular Weight: 150.09 g/mol
Storage Details: Ambient
Harmonised Tariff Code: 2918120000
CAS: 87-69-4
Molecular Formula: C4H6O6
Molecular Weight (g/mol): 150.09
MDL Number: MFCD00064207
InChI Key: FEWJPZIEWOKRBE-UHFFFAOYNA-N
Molecular Weight: 150.09
Appearance Form: crystalline
Color: white
Odor: No data available
Odor Threshold: No data available


pH: 1,0 - 2 at 150 g/l at 25 °C
Melting point/freezing point:
Melting point/range: 170 - 172 °C - lit.
Initial boiling point and boiling range: 179,1 °C at 1.010 hPa
Flash point: 150 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas):
The product is not flammable.
Upper/lower flammability or explosive limits: No data available
Vapor pressure: < 0,05 hPa at 20 °C - NF T 20-048
Vapor density: 5,18 - (Air = 1.0)
Relative density: 1,76 g/cm³ at 20 °C -
Water solubility: 150 g/l at 20 °C - completely soluble

Partition coefficient: n-octanol/water log Pow: -1,91 at 20 °C - OECD
Bioaccumulation is not expected.
Autoignition temperature: 375 °C at 1.015 hPa - NF T 20-036
Decomposition temperature: > 170 °C -
Viscosity:
Viscosity, kinematic: No data available
Viscosity, dynamic: No data available
Explosive properties No data available
Flash Point: 150 °C/302 °F (Lit.)
Hazard Statements: H315-H319-H335
Melting Point: 166 - 176 °C
Optical Rotation: +12 ± 5° (c=2, water)

pH: 2.2 at 25 °C (0.1 N solution)(Lit.)
pKa: pKa1 = 2.98 at 25 °C; pKa2 = 4.34 at 25 °C (Lit.)
Purity: ≥99.0%
Vapor Density 5.18 (vs air)Lit.
Solubility:
Soluble in water (115 g/100 mL at 0 °C; 126 g/100 mL at 10 °C;
139 g/100 mL at 20 °C; 156 g/100 mL at 30 °C; 176 g/100 mL at 40 °C;
195 g/100 mL at 50 °C; 217 g/100 mL at 60 °C; 244 g/100 mL at 70 °C;
273 g/100 mL at 80 °C; 307 g/100 mL at 90 °C; 343 g/100 mL at 100 °C)
Methanol (1 g/1.7 mL)
Ethanol (1 g/3 mL)
Propanol (1 g/10.5 mL)
Ether (1 g/250 mL) or glycerol;
Insoluble in chloroform.

Appearance: Powder
Physical State: Solid
Solubility: Soluble in water
Storage: Store at room temperature
Melting Point: 170-172° C (lit.)
Optical Activity: α20/D +12.4°, c = 20 in water;
α20/D +12°±5°, c = 2 in water
Water Solubility: 161 g/L
logP: -1.3
logP: -1.8
logS: 0.03
pKa (Strongest Acidic): 2.72
pKa (Strongest Basic): -4.3
Physiological Charge: -2
Hydrogen Acceptor Count: 6
Hydrogen Donor Count: 4

Polar Surface Area: 115.06 Ų
Rotatable Bond Count: 3
Refractivity: 26.21 m³·mol⁻¹
Polarizability: 11.33 ų
Molecular Weight: 150.09 g/mol
XLogP3-AA: -1.9
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 6
Rotatable Bond Count: 3
Exact Mass: 150.01643791 g/mol
Monoisotopic Mass: 150.01643791 g/mol
Topological Polar Surface Area: 115 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 134

Isotope Atom Count: 0
Defined Atom Stereocenter Count: 2
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
CAS Number: 87-69-4
Beilstein: 1725147
EC Number: 201-766-0
MDL number: MFCD00064207
PubChem CID: 444305
ChEBI: CHEBI:15671
IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid
SMILES: OC(C(O)C(O)=O)C(O)=O

IUPAC Name: (2R,3R)-2,3-dihydroxybutanedioic acid
Traditional IUPAC Name: L(+)-tartaric acid
Formula: C4H6O6
InChI: InChI=1S/C4H6O6/c5-1(3(7)8)2(6)4(9)10/h1-2,5-6H,(H,7,8)(H,9,10)/t1-,2-/m0/s1
InChI Key: FEWJPZIEWOKRBE-LWMBPPNESA-N
Molecular weight: 150.0868
Exact mass: 150.016437924
SMILES: OC@@HC(O)=O
Molecular Formula / Molecular Weight: C4H6O6 = 150.09
Physical State (20 deg.C): Solid
Storage Temperature: Room Temperature
(Recommended in a cool and dark place, <15°C)
CAS RN: 87-69-4
Reaxys Registry Number: 1725147

PubChem Substance ID: 87576049
Merck Index (14): 9070
MDL Number: MFCD00064207
CAS: 87-69-4
IUPAC Name: 2,3-dihydroxybutanedioic acid
Molecular Formula: C4H6O6
InChI Key: FEWJPZIEWOKRBE-UHFFFAOYNA-N
SMILES: OC(C(O)C(O)=O)C(O)=O
Molecular Weight (g/mol): 150.09
Synonym: (.+-.)-tartaric acid|L-(+)-tartaric acid
MDL Number: MFCD00064207
CAS NUMBER: 87-69-4
MOLECULAR WEIGHT: 150.10
BEILSTEIN REGISTRY NUMBER: 1725147
EC NUMBER: 201-766-0

MDL NUMBER: MFCD00064207
CBNumber: CB8212874
Molecular Formula: C4H6O6
Molecular Weight: 150.09
MDL Number: MFCD00064207
MOL File: 87-69-4.mol
Melting Point: 170-172 °C (lit.)
Alpha: 12º (c=20, H2O)
Boiling Point: 191.59°C (rough estimate)
Density: 1.76
Vapor Density: 5.18 (vs air)
Vapor Pressure: FEMA Number: 3044 | TARTARIC ACID (D-, L-, DL-, MESO-)
Refractive Index: 12.5 ° (C=5, H2O)

Flash Point: 210 °C
Storage Temperature: Store at +5°C to +30°C.
Solubility: H2O: soluble 1M at 20°C, clear, colorless
Form: Solid
pKa: 2.98, 4.34 (at 25°C)
Color: White or colorless
Odor: Odorless at 100.00%
pH: 3.18 (1 mM solution); 2.55 (10 mM solution); 2.01 (100 mM solution)
Odor Type: Odorless
Optical Activity: [α]20/D +13.5±0.5°, c = 10% in H2O
Water Solubility: 1390 g/L (20 °C)
Merck Index: 14, 9070
JECFA Number: 621

BRN: 1725147
Dielectric Constant: 35.9 (-10°C)
Stability: Stable.
Incompatible with oxidizing agents, bases, reducing agents.
InChIKey: FEWJPZIEWOKRBE-JCYAYHJZSA-N
LogP: -1.43
FDA 21 CFR: 184.1099; 582.1099; 582.6099
Substances Added to Food (formerly EAFUS): TARTARIC ACID, L
SCOGS (Select Committee on GRAS Substances): L(+)-tartaric acid
CAS DataBase Reference: 87-69-4 (CAS DataBase Reference)
FDA UNII: W4888I119H
NIST Chemistry Reference: Butanedioic acid, 2,3-dihydroxy- [r-(r*,r*)]-(87-69-4)
EPA Substance Registry System: Tartaric acid (87-69-4)



FIRST AID MEASURES of L(+)-TARTARIC ACID:
-Description of first-aid measures:
General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation: fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of L(+)-TARTARIC ACID:
-Personal precautions, protective equipment and emergency procedures:
Ensure adequate ventilation.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Take up dry.
Clean up affected area.



FIRE FIGHTING MEASURES of L(+)-TARTARIC ACID:
-Extinguishing media:
Suitable extinguishing media:
Water Foam, Carbon dioxide (CO2), Dry powder
Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of L(+)-TARTARIC ACID:
-Control parameters:
Ingredients with workplace control parameters:
-Exposure controls:
Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Protective clothing.
Protective boots, if the situation requires.
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
Protective clothing.
*Hand protection:
Protective gloves.
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of L(+)-TARTARIC ACID:
-Conditions for safe storage, including any incompatibilities:
Storage conditions:
Tightly closed.
Dry.
-Precautions for safe handling:
*Technical measures:
Handling is performed in a well ventilated place.
Wear suitable protective equipment.
Wash hands and face thoroughlyafterhandling.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed.
Store in a cool and dark place.



STABILITY and REACTIVITY of L(+)-TARTARIC ACID:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
-Incompatible materials:
No data available


L-(+)-TARTARIC ACID
L-(+)-Tartaric acid occurs as colorless monoclinic crystals, or a white or almost white crystalline powder.
L-(+)-Tartaric acid is odorless, with an extremely tart taste.
L-(+)-Tartaric acid is a naturally occurring chemical compound found in berries, grapes and various wines.

CAS Number: 87-69-4
Molecular Formula: C4H6O6
Molecular Weight: 150.09
EINECS Number: 201-766-0

Synonyms: ], Weinsaeure, BAROS COMPONENT TARTARIC ACID, L-2,3-DIHYDROXYSUCCINIC ACID, MFCD00064207, C4H6O6, L-tartarate, 4J4Z8788N8, 138508-61-9, (2R,3R)-2,3-Dihydroxybernsteinsaeure, Resolvable tartaric acid, d-alpha,beta-Dihydroxysuccinic acid, TARTARIC ACID (II), TARTARIC ACID [II], 144814-09-5, Kyselina 2,3-dihydroxybutandiova [Czech], REL-(2R,3R)-2,3-DIHYDROXYBUTANEDIOIC ACID, TARTARIC ACID (MART.), TARTARIC ACID [MART.], (1R,2R)-1,2-Dihydroxyethane-1,2-dicarboxylic acid, TARTARIC ACID (USP-RS), TARTARIC ACID [USP-RS], BUTANEDIOIC ACID, 2,3-DIHYDROXY-, (R-(R*,R*)), Tartaric acid D,L, Butanedioic acid, 2,3-dihydroxy- (R-(R*,R*)), TARTARIC ACID (EP MONOGRAPH), TARTARIC ACID [EP MONOGRAPH], Tartarate, L(+) tartaric acid, (2RS,3RS)-Tartaric acid, 2,3-dihydroxy-succinic acid, Traubensaeure, Vogesensaeure, Weinsaure, acide tartrique, acido tartarico, tartaric-acid, para-Weinsaeure, L-Threaric acid, 4ebt, NSC 148314, NSC-148314, (r,r)-tartarate, (+)-tartarate, l(+)tartaric acid, Tartaric acid; L-(+)-Tartaric acid, Tartaric acid (TN), (+/-)-Tartaric acid, Butanedioic acid, 2,3-dihydroxy-, (R*,R*), L-(+) tartaric acid, (2R,3R)-Tartarate, 1d5r, DL TARTARIC ACID, TARTARICUM ACIDUM, 2,3-dihydroxy-succinate, TARTARIC ACID,DL-, SCHEMBL5762, TARTARIC ACID, DL-, Tartaric acid (JP17/NF), TARTARIC ACID [FCC], TARTARIC ACID [JAN], d-a,b-Dihydroxysuccinic acid, MLS001336057, L-TARTARIC ACID [MI], TARTARIC ACID [VANDF], DL-TARTARIC ACID [MI], CCRIS 8978, L-(+)-Tartaric acid, ACS, TARTARIC ACID [WHO-DD], CHEMBL1236315, L-(+)-Tartaric acid, BioXtra, TARTARICUM ACIDUM [HPUS], UNII-4J4Z8788N8, (2R,3R)-2,3-tartaric acid, CHEBI:26849, HMS2270G22, Pharmakon1600-01300044, TARTARIC ACID, DL- [II], TARTARIC ACID, (+/-)-, TARTARIC ACID,DL- [VANDF], HY-Y0293, STR02377, TARTARIC ACID [ORANGE BOOK], EINECS 205-105-7, Tox21_300155, (2R,3R)-2,3-dihydroxysuccinicacid, NSC759609, s6233, AKOS016843282, L-(+)-Tartaric acid, >=99.5%, CS-W020107, DB09459, NSC-759609, (2R,3R)-2,3-dihydroxy-succinic acid, Butanedioic acid, 2,3-dihydroxy-; Butanedioic acid, 2,3-dihydroxy-, (R-(R*,R*)), CAS-87-69-4, L-(+)-Tartaric acid, AR, >=99%, TARTARIC ACID COMPONENT OF BAROS, (R*,R*)-2,3-dihydroxybutanedioic acid, NCGC00247911-01, NCGC00254043-01, BP-31012, SMR000112492, SBI-0207063.P001, (2R,3R)-rel-2,3-dihydroxybutanedioic acid, NS00074184, T0025, EN300-72271, (R*,R*)-(+-)-2,3-dihydroxybutanedioic acid, C00898, D00103, D70248, L-(+)-Tartaric acid, >=99.7%, FCC, FG, L-(+)-Tartaric acid, ACS reagent, >=99.5%, L-(+)-Tartaric acid, BioUltra, >=99.5% (T), J-500964, J-520420, L-(+)-Tartaric acid, ReagentPlus(R), >=99.5%, L-(+)-Tartaric acid, SAJ first grade, >=99.5%, L-(+)-Tartaric acid, tested according to Ph.Eur., Butanedioic acid, 2,3-dihydroxy-, (R*,R*)-(+-)-, L-(+)-Tartaric acid, JIS special grade, >=99.5%, L-(+)-Tartaric acid, natural, >=99.7%, FCC, FG, L-(+)-Tartaric acid, p.a., ACS reagent, 99.0%, L-(+)-Tartaric acid, Vetec(TM) reagent grade, 99%, Q18226455, F8880-9012, Z1147451717, Butanedioic acid, 2,3-dihydroxy-, (theta,theta)-(+-)-, 000189E3-11D0-4B0A-8C7B-31E02A48A51F, L-(+)-Tartaric acid, puriss. p.a., ACS reagent, >=99.5%, L-(+)-Tartaric acid, certified reference material, TraceCERT(R), Tartaric acid, United States Pharmacopeia (USP) Reference Standard, L-(+)-Tartaric acid, anhydrous, free-flowing, Redi-Dri(TM), ACS reagent, >=99.5%, L-(+)-Tartaric acid, p.a., ACS reagent, reag. ISO, reag. Ph. Eur., 99.5%, Tartaric Acid, Pharmaceutical Secondary Standard; Certified Reference Material.

L-(+)-Tartaric acid provides antioxidant properties and contributes to the sour taste within these products.
L-(+)-Tartaric acid belongs to the group of carboxylic acids, and is abundantly found in grapes and wine.
L-(+)-Tartaric acid is widely used in drugs, food, and beverage industry.

L-(+)-Tartaric acid occurs naturally in many fruits as the free acid or in combination with calcium, magnesium, and potassium.
Commercially, L-(+)-Tartaric acid is manufactured from potassium tartrate (cream of tartar), a by-product of wine making.
L-(+)-Tartaric acid is treated with hydrochloric acid, followed by the addition of a calcium salt to produce insoluble calcium tartrate.

This precipitate is then removed by filtration and reacted with 70% sulfuric acid to yield tartaric acid and calcium sulfate.
L-(+)-Tartaric acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes but also in tamarinds, bananas, avocados, and citrus.
Its salt, potassium bitartrate, commonly known as cream of tartar, develops naturally in the process of fermentation.

L-(+)-Tartaric acid is commonly mixed with sodium bicarbonate and is sold as baking powder used as a leavening agent in food preparation.
The acid itself is added to foods as an antioxidant E334 and to impart its distinctive sour taste.
Naturally occurring tartaric acid is a useful raw material in organic chemical synthesis.

L-(+)-Tartaric acid, an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics and is a dihydroxyl derivative of succinic acid.
L-(+)-Tartaric acid, also known as L-tartaric acid, is a naturally occurring organic acid commonly found in plants, particularly in grapes and bananas.
L-(+)-Tartaric acid is a type of tartaric acid with the chemical formula C4H6O6.

L-(+)-Tartaric acid is a tetraric acid that is butanedioic acid substituted by hydroxy groups at positions 2 and 3.
L-(+)-Tartaric acid is a conjugate acid of a L-tartrate(1-).
L-(+)-Tartaric acid is an enantiomer of a D-tartaric acid.

L-(+)-Tartaric acid serves as a donor ligand for biological processes.
L-(+)-Tartaric acid is used as a food additive in candies and soft drinks to impart a sour taste.
L-(+)-Tartaric acid has been known to winemakers for centuries.

However, the chemical process for extraction was developed in 1769 by the Swedish chemist Carl Wilhelm Scheele.
L-(+)-Tartaric acid played an important role in the discovery of chemical chirality.
This property of tartaric acid was first observed in 1832 by Jean Baptiste Biot, who observed its ability to rotate polarized light.

Louis Pasteur continued this research in 1847 by investigating the shapes of sodium ammonium tartrate crystals, which he found to be chiral.
By manually sorting the differently shaped crystals, Pasteur was the first to produce a pure sample of levotartaric acid.
Naturally occurring form of the acid is dextro tartaric acid or L-(+)-Tartaric acid (obsolete name d-tartaric acid).

Because it is available naturally, L-(+)-Tartaric acid is cheaper than its enantiomer and the meso isomer.
The dextro and levo prefixes are archaic terms.
Modern textbooks refer to the natural form as (2R,3R)-tartaric acid (L-(+)-tartaric acid), and its enantiomer as (2S,3S)-tartaric acid (D-(-)-tartaric acid).

The meso diastereomer is referred to as (2R,3S)-tartaric acid or (2S,3R)-tartaric acid.
L-(+)-Tartaric acid and levo form monoclinic sphenoidal crystals[13] and orthorhombic crystals.
Racemic tartaric acid forms monoclinic and triclinic crystals (space group P1).

L-(+)-Tartaric acid crystallizes as monoclinic and triclinic polymorphys depending on the temperature at which crystallization from aqueous solution occurs.
L-(+)-Tartaric acid in Fehling's solution binds to copper(II) ions, preventing the formation of insoluble hydroxide salts.
L-(+)-Tartaric acid isomer of tartaric acid is industrially produced in the largest amounts.

L-(+)-Tartaric acid is obtained from lees, a solid byproduct of fermentations.
The former byproducts mostly consist of potassium bitartrate (KHC4H4O6)
L-(+)-Tartaric acid may be most immediately recognizable to wine drinkers as the source of "wine diamonds", the small potassium bitartrate crystals that sometimes form spontaneously on the cork or bottom of the bottle.

These "tartrates" are harmless, despite sometimes being mistaken for broken glass, and are prevented in many wines through cold stabilization (which is not always preferred since it can change the wine's profile).
The tartrates remaining on the inside of aging barrels were at one time a major industrial source of potassium bitartrate.
L-(+)-Tartaric acid, or "natural" tartaric acid, is abundant in nature, especially in fruits.

Its primary commercial source is as a byproduct of the wine industry.
L-(+)-Tartaric acid is used as an additive in many foods, such as soft drinks, bakery products, and candies.
Industrial uses include tanning, ceramics manufacture, and the production of tartrate esters for lacquers and textile printing.

L-(+)-Tartaric acid is an endogenous metabolite. L-Tartaric acid is the primary nonfermentable soluble acid in grapes and the principal acid in wine.
L-(+)-Tartaric acid can be used as a flavorant and antioxidant for a range of foods and beverages.
L-(+)-Tartaric acid is an orally active weak organic acid that can be isolated from grapes.

L-(+)-Tartaric acid has vasodilatory and antihypertensive effects.
L-(+)-Tartaric acid can be used as flavorings and antioxidants in a range of foods and beverages.
L-(+)-Tartaric acid can be used in laser frequency doubling and optical limiting applications.

L-(+)-Tartaric acid is a white crystalline diprotic acid.
This aldaric acid occurs naturally in many plants, particularly grapes, bananas, and tamarinds, is commonly combined with baking soda to function as a leavening agent in recipes, and is one of the main acids found in wine.
L-(+)-Tartaric acid may be used in the synthesis of (R,R)-1,2-diammoniumcyclohexane mono-(+)-tartrate, an intermediate to prepare an enantioselective epoxidation catalyst.

L-(+)-Tartaric acid may also be used as a starting material in the multi-step synthesis of 1,4-di-O-benzyl-L-threitol.
L-(+)-Tartaric acid can be used a chiral resolving agent for the resolution of 2,2′-bispyrrolidine.
L-(+)-Tartaric acid is widely utilized in pharmaceutical industries.

It is used in soft drinks, confectionaries, food products, gelatin desserts and as a buffering agent.
L-(+)-Tartaric acid forms a compound, TiCl2(O-i-Pr)2 with Diels-Alder catalyst and acta as a chelate agent in metal industries.
Owing to its efficient chelating property towards metal ions, L-(+)-Tartaric acid is used in farming and metal industries for complexing micronutrients and for cleaning metal surfaces, respectively.

This is a natural acid extracted from grapes.
L-(+)-Tartaric acid is used to acidify musts and wines under conditions stipulated by regulation.
The label should indicate in a clear manner that the product is L-tartaric acid, sometimes written L(+)tartaric acid, since its rotatory power is positive.

L-(+)-Tartaric acid must also indicate the purity percentage (greater than 99.5%) and storage requirements.
L-(+)-Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.
L-(+)-Tartaric acid is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.

Used to impart a tart taste in food and beverages, including wine, soft drinks, and candies.
Helps in preserving foods due to its acidic properties.
Stabilizes the color of some foods and beverages.

L-(+)-Tartaric acid is used in combination with sodium bicarbonate to create effervescent tablets.
Acts as an excipient in pharmaceutical formulations.
L-(+)-Tartaric acid is used in cosmetics to adjust the pH level of products.

L-(+)-Tartaric acid utilized in skin care products for its exfoliating properties.
L-(+)-Tartaric acid is used in the textile and tanning industries to complex with metal ions.
Employed in the electroplating industry to adjust the pH of solutions.

Helps in acidifying wine musts and wines to achieve desired acidity levels.
Should be handled with care to avoid inhalation and contact with skin or eyes, as it can cause irritation.
Generally recognized as safe (GRAS) when used in food in accordance with good manufacturing practices.

Melting point: 170-172 °C(lit.)
alpha: 12 º (c=20, H2O)
Boiling point: 191.59°C (rough estimate)
Density: 1.76
vapor density: 5.18 (vs air)
vapor pressure: FEMA: 3044 | TARTARIC ACID (D-, L-, DL-, MESO-)
refractive index: 12.5 ° (C=5, H2O)
Flash point: 210 °C
storage temp.: Store at +5°C to +30°C.
solubility: H2O: soluble1M at 20°C, clear, colorless
form: Solid
pka: 2.98, 4.34(at 25℃)
color: White or colorless
Odor: at 100.00 %. odorless
PH: 3.18(1 mM solution);2.55(10 mM solution);2.01(100 mM solution);
Odor Type: odorless
optical activity: [α]20/D +13.5±0.5°, c = 10% in H2O
Water Solubility: 1390 g/L (20 ºC)
Merck: 14,9070
JECFA Number: 621
BRN: 1725147
Dielectric constant: 35.9(-10℃)
Stability: Stable. Incompatible with oxidizing agents, bases, reducing agents. Combustible.
InChIKey: FEWJPZIEWOKRBE-JCYAYHJZSA-N
LogP: -1.43

L-(+)-Tartaric acid is incompatible with silver and reacts with metal carbonates and bicarbonates (a property exploited in effervescent preparations).
L-(+)-Tartaric acid is a white crystalline diprotic acid.
This aldaric acid occurs naturally in many plants, particularly grapes,bananas, and tamarinds, is commonly combined with baking soda to function as a leavening agent in recipes, and is one of the main acids found in wine.

L-(+)-Tartaric acid is also added to other foods to give a sour taste, and is used as an antioxidant.
Salts of L-(+)-Tartaric acid are known as tartrates.
L-(+)-Tartaric acid is a dihydroxyl derivative of succinic acid.

L-(+)-Tartaric acid is a muscle toxin, which works by inhibiting the production of malic acid, and in high doses causes paralysis and death.
The median lethal dose (LD50) is about 7.5 grams/kg for a human, 5.3 grams/kg for rabbits, and 4.4 grams/kg for mice.
Given this figure, it would take over 500 g (18 oz) to kill a person weighing 70 kg (150 lb) with 50% probability, so it may be safely included in many foods, especially sour-tasting sweets.

As a food additive, tartaric acid is used as an antioxidant with E number E334; tartrates are other additives serving as antioxidants or emulsifiers.
L-(+)-Tartaric acid plays an important role chemically, lowering the pH of fermenting "must" to a level where many undesirable spoilage bacteria cannot live, and acting as a preservative after fermentation.
In the mouth, L-(+)-Tartaric acid provides some of the tartness in the wine, although citric and malic acids also play a role.

L-(+)-Tartaric acid is a white crystalline diprotic acid.
This aldaric acid occurs naturally in many plants, particularly grapes,bananas, and tamarinds, is commonly combined with baking soda to function as a leavening agent in recipes, and is one of the main acids found in wine.

L-(+)-Tartaric acid is also added to other foods to give a sour taste, and is used as an antioxidant.
L-(+)-Tartaric acid is a dihydroxyl derivative of succinic acid.
As a chiral molecule, L-(+)-tartaric acid is used to resolve and separate racemic mixtures into their enantiomers in chemical synthesis and pharmaceutical manufacturing.

L-(+)-Tartaric acid serves as a catalyst in organic reactions, particularly in asymmetric synthesis.
Used in medicine as a chelating agent for certain metal ions and in some medical treatments.
Sometimes used as a dietary supplement due to its antioxidant properties and potential health benefits.

Utilized as a standard reference material in analytical chemistry for calibration and quality control purposes.
Used in laboratories as a reagent for experimental work and research studies in various fields of science.
L-(+)-Tartaric acid is biodegradable and does not persist in the environment under normal conditions.

Generally recognized as safe (GRAS) by regulatory authorities when used in food and pharmaceutical applications.
Proper handling and storage procedures should be followed to prevent exposure and ensure safety.

Widely available from chemical suppliers, pharmaceutical companies, and food ingredient distributors.
Typically sold as a white crystalline powder or as a solution in water.

Uses:
In the soft drink industry, confectionery products, bakery products, gelatin desserts, as an acidulant.
In photography, tanning, ceramics, manufacture of tartrates.
The common commercial esters are the diethyl and dibutyl derivatives used for lacquers and in textile printing. Pharmaceutic aid (buffering agent).

L-(+)-Tartaric acid may be used in the synthesis of (R,R)-1,2-diammoniumcyclohexane mono-(+)-tartrate, an intermediate to prepare an enantioselective epoxidation catalyst.
L-(+)-Tartaric acid may also be used as a starting material in the multi-step synthesis of 1,4-di-O-benzyl-L-threitol.
L-(+)-Tartaric acid can be used a chiral resolving agent for the resolution of 2,2′-bispyrrolidine.

L-(+)-Tartaric acid is widely utilized in pharmaceutical industries.
It is used in soft drinks, confectionaries, food products, gelatin desserts and as a buffering agent.
It forms a compound, TiCl2(O-i-Pr)2 with Diels-Alder catalyst and acta as a chelate agent in metal industries.

Owing to its efficient chelating property towards metal ions, it is used in farming and metal industries for complexing micronutrients and for cleaning metal surfaces, respectively.
L-(+)-Tartaric acid is used in beverages, confectionery, food products, and pharmaceutical formulations as an acidulant.
L-(+)-Tartaric acid may also be used as a sequestering agent and as an antioxidant synergist.

In pharmaceutical formulations, it is widely used in combination with bicarbonates, as the acid component of effervescent granules, powders, and tablets.
L-(+)-Tartaric acid is also used to form molecular compounds (salts and cocrystals) with active pharmaceutical ingredients to improve physicochemical properties such as dissolution rate and solubility.
L-(+)-Tartaric acid and its derivatives have a plethora of uses in the field of pharmaceuticals.

For example, it has been used in the production of effervescent salts, in combination with citric acid, to improve the taste of oral medications.
The potassium antimonyl derivative of the acid known as tartar emetic is included, in small doses, in cough syrup as an expectorant.
L-(+)-Tartaric acid also has several applications for industrial use.

The acid has been observed to chelate metal ions such as calcium and magnesium.
Therefore, the acid has served in the farming and metal industries as a chelating agent for complexing micronutrients in soil fertilizer and for cleaning metal surfaces consisting of aluminium, copper, iron, and alloys of these metals, respectively.
L-(+)-Tartaric acid is widely used as an acidulant in the food industry to impart a sour taste to various products such as beverages (e.g., soft drinks), candies, jams, jellies, and fruit juices.

L-(+)-Tartaric acid is used in baking powder formulations where it reacts with sodium bicarbonate to produce carbon dioxide, causing dough to rise.
In winemaking, L-(+)-Tartaric acid helps adjust and balance acidity levels in grape musts and wines, which is crucial for flavor development and stability.
Due to its chiral nature, L-(+)-tartaric acid is used for resolving racemic mixtures into their respective enantiomers, a process important in pharmaceutical synthesis to produce single-isomer drugs.

L-(+)-Tartaric acid is used in dietary supplements due to its antioxidant properties and potential health benefits.
L-(+)-Tartaric acid is employed in cosmetics and personal care products as a pH adjuster to ensure formulations maintain the desired acidity or alkalinity.
It serves as an ingredient in skin care products for its exfoliating properties and ability to promote skin renewal.

L-(+)-Tartaric acid is used in textile dyeing and printing processes as a mordant to enhance dye uptake and color retention.
It acts as a chelating agent to remove rust and scale from metals in industrial cleaning processes.
L-(+)-Tartaric acid is used as a standard reference material in analytical chemistry for calibration purposes, especially in techniques like chromatography.

L-(+)-Tartaric acid is utilized in electroplating baths to adjust and control the pH of solutions.
L-(+)-Tartaric acid serves as a reagent in various laboratory experiments and research studies.
L-(+)-Tartaric acid is biodegradable and does not persist in the environment.

L-(+)-Tartaric acid is generally recognized as safe (GRAS) for use in food and pharmaceutical applications, though proper handling and storage practices are recommended.
L-(+)-Tartaric acid and its derivatives are utilized as catalysts in chemical reactions, particularly in asymmetric synthesis where the chiral center influences reaction selectivity and efficiency.
L-(+)-Tartaric acid acts as a complexing agent for metal ions in chemical processes and formulations.

L-(+)-Tartaric acid is used in agriculture as an ingredient in certain pesticides and herbicides, contributing to their effectiveness and stability.
In water treatment, L-(+)-Tartaric acid is sometimes used as a scale inhibitor to prevent the buildup of scale deposits in pipes and equipment.
L-(+)-Tartaric acid has historical use in photography as a component of developing solutions for photographic films and papers.

L-(+)-Tartaric acid is included in some oral care products such as toothpaste and mouthwash for its tartar-control properties.
In the pyrotechnics industry, L-(+)-Tartaric acid is used to produce special effects in fireworks due to its ability to enhance coloration.
L-(+)-Tartaric acid is employed in leather tanning processes to modify leather properties and improve quality.

L-(+)-Tartaric acid is considered environmentally friendly due to its biodegradable nature, minimizing environmental impact during use and disposal.
L-(+)-Tartaric acid is derived from natural sources such as grapes and other fruits, aligning with sustainable sourcing practices.

Increasing focus on green chemistry principles is likely to drive innovation in the use of L-(+)-Tartaric acid and its derivatives in environmentally sustainable manufacturing processes.
Ongoing research explores new applications of L-(+)-Tartaric acid in functional foods and nutraceuticals, leveraging its health-promoting properties.

Safety Profile:
Moderately toxic by intravenous route.
Mildly toxic by ingestion.
Reaction with silver produces the unstable silver tartrate.

When heated to decomposition L-(+)-Tartaric acid emits acrid smoke and irritating fumes.
L-(+)-Tartaric acid is widely used in food products and oral, topical, and parenteral pharmaceutical formulations.
L-(+)-Tartaric acid is generally regarded as a nontoxic and nonirritant material; however, strong tartaric acid solutions are mildly irritant and if ingested undiluted may cause gastroenteritis.

Direct contact with L-(+)-Tartaric acid in its solid form or concentrated solutions may cause irritation to the skin, especially in individuals with sensitive skin or prolonged exposure.
Contact with the eyes can cause irritation, redness, and discomfort.
Immediate flushing with water is recommended in case of accidental exposure.

Inhalation of dust or aerosolized particles of L-(+)-Tartaric acid may irritate the respiratory tract, leading to coughing, shortness of breath, or respiratory discomfort.
Ingestion of large quantities of L-(+)-Tartaric acid may cause gastrointestinal irritation, nausea, vomiting, or abdominal discomfort.

L-(+)-TARTARIC ACID

L-(+)-Tartaric acid, commonly known as tartaric acid, is a naturally occurring organic acid found in many plants, particularly in grapes.
L-(+)-Tartaric acid is a white, crystalline solid that is soluble in water and alcohol.
Chemically, tartaric acid belongs to the class of dicarboxylic acids, characterized by having two carboxyl groups (COOH) attached to a carbon chain.

CAS Number: 87-69-4
EC Number: 201-766-0

Tartaric acid, (+)-Tartaric acid, D-Tartaric acid, L-Tartaric acid, 2,3-Dihydroxybutanedioic acid, 2,3-Dihydroxysuccinic acid, Threaric acid, Threoinic acid, Uvic acid, (-)-Tartaric acid, (R)-Tartaric acid, (R)-(+)-Tartaric acid, (R)-(-)-Tartaric acid, L(+)-Tartaric acid, (2R,3R)-2,3-Dihydroxybutanedioic acid, (2R,3R)-2,3-Dihydroxysuccinic acid



APPLICATIONS


L-(+)-Tartaric acid is commonly used in the food and beverage industry as an acidulant and flavoring agent.
L-(+)-Tartaric acid is added to foods and beverages to impart a tart taste and enhance flavor.
L-(+)-Tartaric acid is used in the production of fruit-flavored candies, jams, and jellies.

L-(+)-Tartaric acid is a key ingredient in baking powder, where it reacts with sodium bicarbonate to produce carbon dioxide gas, which leavens baked goods.
L-(+)-Tartaric acid is utilized in winemaking to adjust the acidity of grape must and balance the flavors of wine.

L-(+)-Tartaric acid is added to wine during fermentation to promote clarity and stability.
L-(+)-Tartaric acid is used in the pharmaceutical industry as an ingredient in medications and supplements.

L-(+)-Tartaric acid is utilized as an acidulant and flavoring agent in effervescent tablets and vitamin formulations.
Tartaric acid is employed in the cosmetic industry in skincare products such as exfoliating scrubs and chemical peels.

L-(+)-Tartaric acid helps to remove dead skin cells, unclog pores, and promote skin renewal.
L-(+)-Tartaric acid is used in the production of metal cleaning solutions and rust removers.
L-(+)-Tartaric acid acts as a chelating agent, binding to metal ions and facilitating their removal from surfaces.

Tartaric acid is utilized in the textile industry for dyeing and finishing processes.
L-(+)-Tartaric acid helps to fix dyes to fibers and improve colorfastness.

L-(+)-Tartaric acid is added to cleaning agents and detergents as a pH buffer and water softener.
L-(+)-Tartaric acid enhances the cleaning efficiency of these products and prevents mineral deposits on surfaces.

Tartaric acid is used in the manufacturing of adhesives and sealants as a cross-linking agent.
L-(+)-Tartaric acid helps to improve the adhesion and durability of these materials.
L-(+)-Tartaric acid is employed in the production of photography chemicals as a developing agent.

L-(+)-Tartaric acid helps to reduce silver halides to metallic silver during film processing.
L-(+)-Tartaric acid is used in the leather industry for tanning and finishing processes.
L-(+)-Tartaric acid helps to stabilize collagen fibers and improve the quality of leather products.

L-(+)-Tartaric acid is utilized in the production of ceramics and glass as a fluxing agent.
L-(+)-Tartaric acid lowers the melting point of raw materials and promotes uniform melting and shaping.
Tartaric acid is employed in agricultural applications as a soil conditioner and plant nutrient.

L-(+)-Tartaric acid is utilized in the production of carbonated beverages as a flavoring agent and acidity regulator.
L-(+)-Tartaric acid enhances the tartness and refreshment of soft drinks, colas, and sparkling water.
L-(+)-Tartaric acid is added to fruit juices and fruit-flavored drinks to balance sweetness and acidity.

In the confectionery industry, L-(+)-Tartaric acid is used to impart a sour taste to candies, gummies, and sour powders.
L-(+)-Tartaric acid contributes to the tanginess and flavor intensity of sour candies and confectionery products.

L-(+)-Tartaric acid is employed in the preparation of gelatin desserts and fruit-flavored gelatin molds.
L-(+)-Tartaric acid helps to stabilize gelatin and improve its texture and consistency.

The compound is added to canned fruits and vegetables as a preservative to maintain color and freshness.
L-(+)-Tartaric acid is utilized in the production of fruit jams, jellies, and preserves to enhance flavor and promote gel formation.

L-(+)-Tartaric acid is added to salad dressings and marinades as a flavor enhancer and emulsifying agent.
L-(+)-Tartaric acid is used in the brewing industry to adjust the acidity of beer and improve flavor stability.

L-(+)-Tartaric acid helps to balance the sweetness and bitterness of beer and prevent off-flavors.
The compound is employed in the dairy industry in the production of yogurt and cheese to enhance acidity and texture.

L-(+)-Tartaric acid is utilized in the textile printing process as a mordant to fix dyes to fabrics and improve color retention.
It is added to metalworking fluids as a corrosion inhibitor and pH buffer to protect metal surfaces from rust and degradation.

L-(+)-Tartaric acid is used in electroplating solutions as a complexing agent to improve the deposition of metal coatings.
L-(+)-Tartaric acid is added to antifreeze solutions as a pH buffer and stabilizer to prevent corrosion in automotive cooling systems.

L-(+)-Tartaric acid is employed in the production of synthetic resins and polymers as a cross-linking agent to improve mechanical properties.
L-(+)-Tartaric acid is used in the manufacture of paper and pulp to adjust pH levels and enhance pulp bleaching processes.

L-(+)-Tartaric acid is utilized in the oil and gas industry in the production of drilling fluids as a pH buffer and viscosity modifier.
L-(+)-Tartaric acid is added to water treatment chemicals as a scale inhibitor to prevent mineral deposits in pipes and equipment.

L-(+)-Tartaric acid is used in the production of detergents and cleaning agents as a chelating agent to remove metal ions and improve cleaning efficiency.
L-(+)-Tartaric acid is employed in the construction industry as an additive in cement and concrete formulations to improve workability and reduce setting time.

L-(+)-Tartaric acid is added to personal care products such as toothpaste and mouthwash as a pH adjuster and tartar control agent.
Overall, L-(+)-Tartaric acid plays a vital role in a wide range of applications across numerous industries, contributing to its versatility and importance.



DESCRIPTION


L-(+)-Tartaric acid, commonly known as tartaric acid, is a naturally occurring organic acid found in many plants, particularly in grapes.
L-(+)-Tartaric acid is a white, crystalline solid that is soluble in water and alcohol.
Chemically, tartaric acid belongs to the class of dicarboxylic acids, characterized by having two carboxyl groups (COOH) attached to a carbon chain.

The chemical formula of L-(+)-Tartaric acid is C4H6O6, and its molar mass is approximately 150.09 grams per mole.
L-(+)-Tartaric acid is optically active and exists in two enantiomeric forms: L-(+)-tartaric acid and D-(-)-tartaric acid.
The L-(+)-tartaric acid isomer is the biologically active form found in living organisms.

L-(+)-Tartaric acid has a variety of applications across different industries.
In the food and beverage industry, it is commonly used as an acidulant and flavoring agent.
L-(+)-Tartaric acid contributes to the tartness of certain foods and beverages and is often added to jams, jellies, soft drinks, and wine to enhance their flavor profile.

L-(+)-Tartaric acid is a naturally occurring organic compound found in many fruits, particularly grapes.
L-(+)-Tartaric acid is a white, crystalline solid with a tart taste and acidic smell.
The chemical formula of L-(+)-Tartaric acid is C4H6O6, and its molar mass is approximately 150.09 grams per mole.

L-(+)-Tartaric acid is optically active and exists in two enantiomeric forms: L-(+)-tartaric acid and D-(-)-tartaric acid.
L-(+)-Tartaric acid is soluble in water and alcohol, making it versatile for various applications.

L-(+)-Tartaric acid has two carboxylic acid functional groups, which contribute to its acidity and reactivity.
L-(+)-Tartaric acid has a melting point of approximately 171-174°C.
L-(+)-Tartaric acid is commonly found in nature as the potassium salt, potassium bitartrate, known as cream of tartar.

L-(+)-Tartaric acid plays a crucial role in winemaking, where it helps regulate acidity and stabilize wines.
L-(+)-Tartaric acid is also used in the baking industry as a leavening agent in conjunction with baking soda.

L-(+)-Tartaric acid contributes to the rise and texture of baked goods such as cakes, cookies, and bread.
L-(+)-Tartaric acid is utilized in the pharmaceutical industry as an ingredient in medications and dietary supplements.

L-(+)-Tartaric acid is added to effervescent tablets to produce carbon dioxide gas when dissolved in water.
L-(+)-Tartaric acid is utilized in cosmetic products such as skincare masks and exfoliating scrubs for its skin-renewing properties.

L-(+)-Tartaric acid is used in metal cleaning solutions and rust removers for its chelating abilities.
L-(+)-Tartaric acid helps remove mineral deposits and stains from metal surfaces.

L-(+)-Tartaric acid is employed in the textile industry for dyeing and finishing processes.
L-(+)-Tartaric acid acts as a mordant, helping to fix dyes to fibers and improve colorfastness.

L-(+)-Tartaric acid is utilized in cleaning agents and detergents as a pH buffer and water softener.
L-(+)-Tartaric acid is added to adhesives and sealants to improve their adhesion and durability.

The compound is used in photography chemicals as a developing agent, aiding in the production of photographic prints.
L-(+)-Tartaric acid is employed in the ceramic and glass industry as a fluxing agent, facilitating the melting and shaping of raw materials.
L-(+)-Tartaric acid is utilized in agricultural applications as a soil conditioner and plant nutrient.

L-(+)-Tartaric acid helps improve soil structure and fertility, leading to better plant growth and crop yield.
Overall, L-(+)-Tartaric acid is a versatile compound with diverse applications across various industries, contributing to its importance and widespread use.



PROPERTIES


Chemical Formula: C4H6O6
Molecular Weight: Approximately 150.09 grams per mole
Physical State: Solid at room temperature (crystalline)
Color: White
Odor: Odorless
Taste: Tart or sour
Solubility in Water: Soluble
Solubility in Organic Solvents: Soluble in alcohol, slightly soluble in ether
Melting Point: Approximately 171-174°C
Boiling Point: Decomposes before boiling
Density: Approximately 1.79 g/cm³
pH: Acidic (approximately 2.2 at 1% solution)
Optical Activity: Optically active (D-tartaric acid rotates polarized light to the right, L-tartaric acid rotates it to the left)
Hygroscopicity: Low
Stability: Stable under normal conditions
Flammability: Non-flammable
Refractive Index: Approximately 1.63
Dielectric Constant: Approximately 10.5
Heat of Combustion: Approximately -1575 kJ/mol
Heat of Fusion: Approximately 53 kJ/mol
Heat of Vaporization: Approximately 106 kJ/mol
Specific Heat Capacity: Approximately 0.868 J/g°C
Flash Point: Not applicable (solid)
Surface Tension: Approximately 105 mN/m
Viscosity: Varies with concentration and temperature



FIRST AID


Inhalation:

If inhaled, immediately remove the affected person to fresh air.
Allow the person to rest in a well-ventilated area.
If breathing difficulties persist, seek medical attention promptly.
Provide oxygen if the person has difficulty breathing.


Skin Contact:

Remove contaminated clothing and shoes immediately.
Wash the affected area with plenty of soap and water for at least 15 minutes.
Rinse skin thoroughly to remove any traces of the substance.
If irritation, redness, or rash develops, seek medical advice.
Apply a soothing moisturizer or barrier cream to the affected area to help alleviate discomfort.


Eye Contact:

Flush eyes with lukewarm water, keeping eyelids open, for at least 15 minutes.
Remove contact lenses if present and easily removable.
Seek immediate medical attention if irritation, pain, or redness persists.
Protect the unaffected eye to prevent contamination.


Ingestion:

Rinse mouth with water and drink plenty of water to dilute the substance.
Do not induce vomiting unless instructed to do so by medical personnel.
Seek medical attention immediately and provide information on the ingested substance.
Do not give anything by mouth to an unconscious person.


General Advice:

Keep affected person calm and reassure them.
If seeking medical attention, provide the Safety Data Sheet (SDS) or product label information to healthcare providers.
If the substance has entered the respiratory tract, monitor for signs of respiratory distress and administer CPR if necessary.
Do not administer any medications unless directed by medical personnel.
If exposed to large quantities or experiencing severe symptoms, seek emergency medical assistance immediately.
Be prepared to provide information on the specific product, concentration, and duration of exposure when seeking medical advice.
If transporting an affected individual to a medical facility, ensure proper ventilation and monitor their condition closely.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
Wear suitable protective clothing, including gloves, safety glasses, and a lab coat, when handling L-(+)-Tartaric acid to prevent skin contact and eye irritation.
Use respiratory protection, such as a dust mask or respirator, if handling in powdered form or in poorly ventilated areas to prevent inhalation of dust particles.

Ventilation:
Handle L-(+)-Tartaric acid in a well-ventilated area or under a fume hood to minimize exposure to airborne particles and vapors.
Ensure adequate ventilation in storage areas to prevent the accumulation of vapors and maintain air quality.

Avoidance of Contamination:
Prevent contamination of L-(+)-Tartaric acid by keeping containers tightly closed when not in use.
Do not allow the substance to come into contact with incompatible materials, such as strong oxidizing agents or bases, to avoid hazardous reactions.

Safe Handling Practices:
Avoid generating dust or aerosols when handling L-(+)-Tartaric acid.
Use appropriate handling tools, such as scoops or spatulas, to minimize skin contact and prevent spills.
Do not eat, drink, or smoke while handling L-(+)-Tartaric acid to prevent accidental ingestion.

Emergency Procedures:
Familiarize yourself and other personnel with emergency procedures in case of spills, leaks, or exposure incidents.
Have appropriate spill control measures, absorbent materials, and personal protective equipment readily available.


Storage:

Storage Conditions:
Store L-(+)-Tartaric acid in a cool, dry, well-ventilated area away from sources of heat, moisture, and direct sunlight.
Keep containers tightly closed when not in use to prevent contamination and moisture absorption.

Temperature and Humidity:
Maintain storage temperature within the recommended range (typically room temperature) to ensure stability and minimize degradation.
Avoid exposure to extreme temperatures or fluctuations, as this may affect the quality and shelf life of the product.

Compatibility:
Store L-(+)-Tartaric acid away from incompatible materials, such as strong oxidizing agents, alkalis, and reducing agents, to prevent hazardous reactions.
Segregate L-(+)-Tartaric acid from other chemicals to avoid cross-contamination and potential hazards.

Labeling and Identification:
Clearly label storage containers with the product name, hazard warnings, handling instructions, and date of receipt.
Ensure proper identification and labeling of L-(+)-Tartaric acid to prevent confusion and facilitate safe handling and storage.

Security Measures:
Restrict access to storage areas containing L-(+)-Tartaric acid to authorized personnel only.
Implement appropriate security measures, such as locked cabinets or storage rooms, to prevent unauthorized access or tampering.

Spill Containment and Cleanup:
Have spill containment kits, absorbent materials, and personal protective equipment readily available for spill cleanup.
Follow established spill cleanup procedures and disposal guidelines to minimize environmental impact and ensure safety.

Regulatory Compliance:
Store and handle L-(+)-Tartaric acid in compliance with local regulations, codes, and guidelines governing the storage and handling of hazardous substances.
Maintain accurate records of storage conditions, inventory levels, and handling procedures for regulatory compliance and safety auditing purposes.
LABSA
LABSA; Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkylbenzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique; cas no: 27176-87-0
LABSA LIQUID
LABSA LIQUID Linear Alkyl Benzene Sulphonic Acid Chemical Name: Linear Alkyl Benzene Sulphonic Acid; Linear Alkyl Benzene Sulphonic Acid Description and Uses: Linear Alkyl Benzene Sulphonic Acid; is an anionic surfactant commonly used in the manufacture of detergents and emulsifiers. It is environmentally friendly as it can be dried as powder. Usage areas LABSA Liquid is formed by the reaction of Linear Alkyl Benzene Sulphonic Acid (LAB) with SO3 (sulfonation). Today, LABSA Liquid is used as the main surfactant in liquid, gel or powder detergent production processes. It is one of the main raw materials of synthetic detergent industry. Laundry, dishwasher powder detergents, detergent gels, liquid soaps, cleaning powders, oily soaps and so on. as. It is used as mercerizing and washing agent in textile sector. As the raw material of detergent, it is used in the production of alkynbenzene solphonic acid sodium in decontamination, emulsion, dispersion performance, wetting and foam properties. It is widely used in various detergent and emulsion production such as washing powder, dishwashing detergent, light or hard dirt detergent, textile industry cleaner, paint assistant, coating and leather making industry and paper making industry. PRODUCT IDENTIFICATION CAS NO. 27176-87-0 LINEAR ALKYL BENZENE SULPHONIC ACID EINECS NO. 248-289-4 FORMULA CH3(CH2)11C6H4SO3H SYNONYMS Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA Liquid; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkyl benzene Sulphonic Acid; Dodecylbenzolsulfonsäure (German); ácido dodecilbenceno sulfónico (Spanish); Acide dodécylbenzènesulfonique (French); CLASSIFICATION Anionic Surfactant DESCRIPTION OF LABSA Liquid Linear alkyl benzene sulphonic acid is the largest-volume synthetic surfactant because of its relatively low cost, good performance, the fact that it can be dried to a stable powder and the biodegradable environmental friendliness as it has straight chain. LABSA Liquid is an anionic surfactants with molecules characterized by a hydrophobic and a hydrophilic group. Alpha-olefin sulfonates (AOS) alkyl sulfates (AS) are also examples of commercial anionic surfactants. They are nonvolatile compounds produced by sulfonation. LABSA Liquid are complex mixtures of homologues of different alkyl chain lengths (C10 to C13 or C14) and phenyl positional isomers of 2 to 5-phenyl in proportions dictated by the starting materials and reaction conditions, each containing an aromatic ring sulfonated at the para position and attached to a linear alkyl chain at any position with the exception of terminal one (1-phenyl). The properties of LABSA Liquid differ in physical and chemical properties according to the alkyl chain length, resulting in formulations for various applications. The starting material LABSA Liquid (linear alkylbenzene) is produced by the alkylation of benzene with n-paraffins in the presence of hydrogen fluoride (HF) or aluminium chloride (AlCl3) as a catalyst. LABSA Liquid is produced by the sulfonation of LAB with oleum in batch reactors. Other sulfonation alternative reagents are sulfuric acid, diluted sulfur trioxide, chlorosulfonic acid and sulfamic acid on falling film reactors. LABSA Liquid are then neutralized to the desired salt (sodium, ammonium, calcium, potassium, and triethanolamine salts). Surfactants are widely used in the industry needed to improve contact between polar and non-polar media such as between oil and water or between water and minerals. Linear alkyl benzene sulphonic acid is mainly used to produce household detergents including laundry powders, laundry liquids, dishwashing liquids and other household cleaners as well as in numerous industrial applications like as a coupling agent and as an emulsifier for agricultural herbicides and in emulsion polymerization. PHYSICAL AND CHEMICAL PROPERTIES Household detergents including laundry powders, laundry liquids, dishwashing liquids and other household cleaners. Industrial applications of wetting agent, emulsifier for agricultural herbicides and in polymerization. LABSA Liquid HOMOLOGUES AND SALTS Linear Alkyl benzene Sulphonic Acid (LABSA Liquid)/Linear Alkylate Sulfonate (LAS) Linear alkyl benzene sulphonic acid (LABSA Liquid) is prepared commercially by sulfonating linear alkylbenzene (LAB). Linear alkylbenzene sulfonate (LABSA Liquid), the world’s largest-volume synthetic surfactant, which includes the various salts of sulfonated alkylbenzenes, is widely used in household detergents as well as in numerous industrial applications. The LABSA Liquid market is driven by the markets for LABSA Liquid, primarily household detergents. Linear alkylbenzene sulfonate was developed as a biodegradable replacement for nonlinear (branched) alkylbenzene sulfonate (BAS) and has largely replaced BAS in household detergents throughout the world. The pattern of LABSA Liquid consumption demonstrates the overwhelming preference by consumers for liquid laundry detergents in North America, whereas powders continue to be the dominant products in Western Europe, Japan, and China. Comparable and reliable data in other world regions are generally unavailable. In these less-developed world areas, LABSA Liquid is essentially used only in laundry powders (particularly in India and Indonesia) and hand dishwashing liquids. The latter are often used as general-purpose cleaners. The following pie chart shows world consumption of LABSA Liquid: About 82–87% of LABSA Liquid is used in household detergents, including laundry powders, laundry liquids, dishwashing liquids, and other household cleaners. Industrial, institutional, and commercial cleaners account for most of the other applications, but LABSA Liquid is also used as an emulsifier (e.g., for agricultural herbicides and in emulsion polymerization) and as a wetting agent. Very small volumes are also used in personal care applications. Demand in the North American household segment fell sharply in 2000–11, as a result of several developments, including reformulations away from LABSA Liquid to alternative surfactants because of cost considerations, the greater use of enzymes, and adverse economic conditions that resulted in lower overall surfactant levels in detergents. However, consumption stabilized during 2011–17. Although consumption of LABSA Liquid will likely stabilize or decline slightly in the highly developed regions, it will increase by 3.0–5.0% in some less-developed regions or countries, such as the Middle East, Africa, India, and China, as well as Southeast Asia. As a result of the rapid growth of LABSA Liquid demand in the Asia Pacific region, demand in the region accounted for over half of global demand in 2017. The worldwide growth of LABSA Liquid will be negatively impacted by the efforts of detergent manufacturers to reduce the active content in their surfactant formulations, by the shift to liquid detergents in some countries (which benefits competing surfactants), and by less consumer overdosing (particularly in North America with unit dose laundry products, assuming they continue to take some market share from traditional liquid detergents). However, consumption of LABSA Liquid will be positively affected in countries/regions such as India, China, Africa, and the Middle East, where powder detergents are still a very large part of the laundry detergent market. Linear alkylbenzene sulfonate competes with several other major surfactants for use in household detergents. Some of the competitive surfactants have greater hard-water tolerance and better compatibility with enzymes and are milder than LABSA Liquid. Historically, however, LABSA Liquid has most often been lower in cost and has had other more favorable properties compared with competing surfactants. During 2002–06, very high crude oil prices made LABSA Liquid far less competitive than had been true in most years since its introduction. During 2007–11, LABSA Liquid prices tracked more closely those of the competitive surfactants. This led to a more stable pattern of consumption, even as prices for all surfactants continued to be very volatile. From late 2014 through 2017, low crude oil prices helped LABSA Liquid become more competitive. LABSA Liquid/LAS production is impacted by the supply situation for competing products—mainly alcohol ether sulfates (AES). Shortages in AES supply or its high price has usually favored the use of LABSA Liquid/LAS. In the developing world, LABSA Liquid competes with soaps. Alkylbenzene sulfonates are a class of anionic surfactants, consisting of a hydrophilic sulfonate head-group and a hydrophobic alkylbenzene tail-group. Along with sodium laureth sulfate they are one of the oldest and most widely used synthetic detergents and may be found in numerous personal-care products (soaps, shampoos, toothpaste etc.) and household-care products (laundry detergent, dishwashing liquid, spray cleaner etc.).[1] They were first introduced in the 1930s in the form of branched alkylbenzene sulfonates (BAS) however following environmental concerns these were replaced with linear alkylbenzene sulfonates (LABSA Liquid) during the 1960s.[2] Since then production has increased significantly from about 1 million tons in 1980, to around 3.5 million tons in 2016, making them most produced anionic surfactant after soaps. Linear alkylbenzene sulfonates (LAS) are prepared industrially by the sulfonation of linear alkylbenzenes (LABSA Liquid), which can themselves be prepared in several ways.[2] In the most common route benzene is alkylated by long chain monoalkenes (e.g. dodecene) using hydrogen fluoride as a catalyst.[9] The purified dodecylbenzenes (and related derivatives) are then sulfonated with sulfur trioxide to give the sulfonic acid.[10] The sulfonic acid is subsequently neutralized with sodium hydroxide.[1] The term "linear" refers to the starting alkenes rather than the final product, perfectly linear addition products are not seen, in-line with Markovnikov's rule. Thus, the alkylation of linear alkenes, even 1-alkenes such as 1-dodecene, gives several isomers of phenyldodecane.[11] Structure property relationships Under ideal conditions the cleaning power of BAS and LABSA Liquid is very similar, however LABSA Liquid performs slightly better in normal use conditions, due to it being less affected by hard water.[12] Within LABSA Liquid itself the detergency of the various isomers are fairly similar,[13][14] however their physical properties (Krafft point, foaming etc.) are noticeably different.[15][16] In particular the Krafft point of the high 2-phenyl product (i.e. the least branched isomer) remains below 0 °C up to 25% LABSA Liquid whereas the low 2-phenyl cloud point is ∼15 °C.[17] This behavior is often exploited by producers to create either clear or cloudy products.. LABSA Liquid Linear Alkyl Benzene Sulphonic Acid Product Information LABSA Liquid Linear alkyl benzene Sulphonic Acid is a chemical which is colorless and have viscous properties. LABSA Liquid Linear alkyl benzene sulphonic acid mainly using in detergent formulations. It is one of the most important and cheapest surfactants in powder formulation and detergent fluids. It has excellent cleansing properties. Usages of Linear Alkyl Benzene Sulphonic Acid LABSA Liquid Linear Alkyl Benzene sulphonic acid is a batch of organic sulfur compounds that are used in most home detergents, dishwashing detergents, detergent powder, cleaning powder, washing powders, detergent cake, liquid soap, soaps etc. LABSA Liquid, sulfonic acid compound is used as a foaming agent, cleaning agent in more formulations and toilet soaps for foaming. Sulfonic acid, LABSA Liquid is using in detergent industries, in textile industry as a washing agent, pesticides industries to improve the quality of spray. Sulfonic acid, LABSA Liquid is not inflammable substance and can dissolve in water, but not in organic solvent. industrial uses. LABSA Liquid Linear alkyl benzene Sulphonic Acid uses in produce sulfonic acid. LABSA Liquid is an additive as a LABSA Liquid Linear alkyl benzene Sulphonic Acid packing Basekim Chemical Production can supply LABSA Liquid Linear alkyl benzene Sulphonic Acid with drum. Each drum can take 220 kg and 80 drum can easily load in a container. It also depends on customer demands as well. LABSA Liquid Linear alkyl benzene Sulphonic Acid LABSA Liquid Linear alkyl benzene Sulphonic Acid is a chemical which is colorless and have viscous properties. LABSA Liquid Linear alkyl benzene Sulphonic Acid mainly using in detergent formulations. It is one of the most important and cheapest surfactants in powder formulation and detergent fluids. It has excellent cleansing properties. LABSA Liquid Linear alkyl benzene Sulphonic Acid in the formulation of anionic, non-anionic, and amphoteric surfactants, and it is extremely important for its degradability in nature. It is soluble in water and emulsifying agent. Linear Alkyl benzene sulphonic acid is one of the most widely used anionic surfactants due to its low cost, high efficiency and biocompatibility due to its linear chain. This anionic surfactant has hydrophilic and hydrophobic groups. These are non-volatile compounds produced by the sulfonation process. These compounds consist of mixtures of carbon chains of 10 to 14 carbon lengths that are a phenyl group with a sulfonate group LABSA Liquid Linear alkyl benzene Sulphonic Acid LABSA Liquid Linear alkyl benzene Sulphonic Acid application The properties of LABSA Liquid Linear alkyl benzene Sulphonic Acid depend on the length of the alkane chains that give them different functionality. Surfactants are used in the industry to increase the contact of polar and non-polar phases, such as oil, water, or water and minerals. Linear alkyl benzene Sulphonic Acid sulfonate is mainly used for the manufacture of household detergents such as laundry powder, washing liquid, dishwashing liquid and other household cleaners and other industrial uses. LABSA Liquid Linear alkyl benzene Sulphonic Acid uses in produce sulfonic acid. LABSA Liquid is an additive as an lubricating agent oils and have as corrosion and rust prevention. his product is a very effective intermediate surfactant. It is usually neutralized with alkali types and forms sulphonates used in different fields. This product can be used in acidic environments. LABSA Liquid Linear alkyl benzene Sulphonic Acid packing can supply LABSA Liquid Linear alkyl benzene Sulphonic Acid with drum . Each drum can take 220 kg and 80 drum can easily load in a container LABSA Liquid Linear alkyl benzene Sulphonic Acid PACKING Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) Specification LABSA Liquid properties: 1. Linear alkyl benzene sulphonic acids (LABSA Liquid) are anionic surfactants. Linear alkyl benzene Synonyms LAS;LABSA Liquid;LABS;Laurylbenzenesulfonic Acid;Laurylbenzenesulfonate;Linear Alkyl benzene Sulphonic Acid;DDBSA;Dodecyl Benzene Sulphonic Acid;Dodecyl Benzene Sulfonic Acid Linear alkyl benzene sulphonic acid, also known as LABSA Liquid is a synthetic chemical surfactant, which is a widely used industrial detergent. It is used in washing powder, detergent powder, oil soap, cleaning powder and detergent cake. DESCRIPTION LABSA Liquid is an anionic surfactant, whose molecules are characterized by a hydrophilic and a hydrophobic group. This nonvolatile chemical compound is synthesized through the process of sulfonation. The sulfonation reagents include sulfuric acid, chlorosulfonic acid, sulfamic acid and diluted sulfur trioxide. The properties of LABSA Liquid, differs in chemical and physical properties based on the length of the alkyl chain. This results in formulations, which finds many applications. The resulting surfactants are used in the chemical industry to improve contact between water and minerals. USES LABSA Liquid is chiefly used in the detergent industry for the manufacture of washing powder, detergent powder, detergent cake, liquid soap, oil soap, scouring bar and cleaning powder. This chemical finds applications in anionic specialty formulations. The quality of pesticide sprays can be improved from it. Linear alkyl benzene sulphonic acid is used as a washing and mercerizing agent in the textile industry. The surface area of distempers is increased using LABSA Liquid. It is used as a wetting agent as well as an emulsifier in small quantities along with other surfactants, for foaming of toilet soaps. Owing to its high active matter content and miscibility with low salt content and water, LABSA Liquid is used in the polymerization of emulsions and in production of coupling agents, emulsifiers, agricultural herbicides, household and industrial cleaners. ENVIRONMENTAL AND SAFETY CONSIDERATIONS Most anionic surfactants including LABSA Liquid are nontoxic in nature. However, prolonged exposure to these surfactants, could irritate and damage the skin through the disruption of the lipid membrane, which protects the skin and other cells. On the other hand, the biodegradability is determined by surfactant's hydrophobic hydrocarbon group. ADVANTAGES Linear Alkyl Benzene Sulphonic Acid is one of the largest synthetic surfactants by volume due to its low cost and high performance. Apart from this, LABSA Liquid can be dried to a stable powder form. This chemical is biodegradable and environmentally friendly. Buy excess stock of LABSA Liquid for a discounted price. Product Description Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 90% is the largest-volume synthetic surfactant because of its relatively low cost, good performance, the fact that it can be dried to a stable powder and the biodegradable environmental friendliness. LAB Sulphonic Acid is an anionic surfactant widely used in formulation of all ranges of Domestic Detergents Powder ,Cake & Dish wash cleaners. Linear Alkyl Benzene Sulphonic Acid Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 90% is the largest-volume synthetic surfactant because of its relatively low cost, good performance, the fact that it can be dried to a stable powder and the biodegradable environmental friendliness. LAB Sulphonic Acid is an anionic surfactant widely used in formulation of all ranges of Domestic Detergents Powder ,Cake & Dish wash cleaners. Due to its high active matter , miscibility with water and low salt content , it is also used in formulation of Industrial & Household liquid cleaners as well as in numerous industrial applications like as a coupling agent and as an emulsifier for agricultural herbicides and in emulsion polymerization. Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 90% - Soft Acid Slurry is main raw material for: Properties of LABSA Liquid Nature Anionic Constitution Sulphonated Linear Alkyl Benzene Sulphonic Acid Appearance Light Yellow-Brown viscous liquid Solubility Readily soluble in water Specifications of LABSA Liquid Active matter ( % by weight) 90 ± 1% Non-Digestive oil matter( % by weight) 1% Max Free Sulphuric acid % by weight) 7 Max Color [KLETT] (When dispatched) 30 Avg Advantages of LABSA Liquid 90 % over LABSA Liquid 96 % Cost Factor Cost of LABSA Liquid 90% Sulphonation Plant is 1/10th as compared to LABSA Liquid 96 % Sulphonation plant thereby giving huge cost advantage as a result of which LABSA Liquid 90% can be offered to consumers at competitive prices vis-a-vis LABSA Liquid 96% LABSA Liquid 90 % has 5-6 % Free Acid which is converted to Glauber Salt (Sodium Sulphate) on reaction with Soda Ash which is the common ingredient for all Detergent Powders. This Glauber Salt helps in keeping End Product i.e Detergent Powder free flowing and imparts anti-caking properties which is absent in Detergents formulated with LABSA Liquid 96 % LINEAR ALKYL BENZENE SULPHONIC ACID/ SODIUM ALKYL BENZENE SULFONATE / LABSA Liquid/ SODIUM DODYL BENZENE SULFONATE Anionic surfactant used in all cleaning & detergent products like dishwashing liquid, all purpose cleaner, laundry liquid , car shampoo, degreasers and in so many industrial cleaners. LABSA Liquid is acidic & has to be neutralized with any of caustic soda, potassium hydroxide or TEA ( you can also order them from us). We are providing LABSA Liquid as below 1. pure acid LABSA Liquid/ linear alkyl benzene sulphonic acid/ dodyl benzene 2. ready neutralized LABSA Liquid..LABSA Liquid sodium salt/ sodium dodyl benzene sulfonate 40%. ..................................Uniclean america......................... sizes are :- plastic HDPE : 16 oz, 32 oz, 64 oz, 128 oz, 5 gallon & 20 liter . Linear Alkyl Benzene Sulphonic Acid| LABSA Liquid Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is a largest volume surfactant because of its low cost, good performance; environmental friendliness .For the production of Linear Alkyl Benzene sulphonic acid, LABSA Liquid, alkaline benzene linear sulfation is usually used. Its components: linear alkyl benzene Sulphonic Acid, oxygen, sulfur and citric acid. (LABSA Liquid) Linear Alkyl Benzene Sulphonic Acid| LABSA Liquid used in: Linear Alkyl Benzene Sulphonic acid, LABSA Liquid is a batch of organic sulfur compounds that are used in most home detergents, dishwashing detergents, detergent powder, cleaning powder, washing powders, detergent cake, liquid soap, soaps etc. LABSA Liquid, sulfonic acid compound is used as a foaming agent , cleaning agent in more formulations and toilet soaps for foaming. Linear Alkyl Benzene Sulphonic acid, LABSA Liquid is using in detergent industries, in textile industry as a washing agent, pesticides industries to improve the quality of spray. Sulfonic acid, LABSA Liquid is not inflammable substance and can dissolve in water, but not in organic solvent. Definition Linear Alkyl Benzene Sulphonic Acid Definition Linear Alkyl Benzene Sulphonic Acid, Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) LABSA Liquid properties: Chemical Name: Linear Alkyl Benzene Sulphonic Acid Synonyms: LABSA Liquid;LABS;Laurylbenzenesulfonic Acid;Laurylbenzenesulfonate;Linear Alkyl benzene Sulphonic Acid;DDBSA;Dodecyl Benzene Sulphonic Acid; Dodecyl Benzene Sulfonic Acid Formula Linear Alkyl Benzene Sulphonic Acid Storage Linear Alkyl Benzene Sulphonic Acid | LABSA Liquid Linear Alkyl Benzene Sulphonic Acid Stored in cool, ventilated and dry place, kept away from sunshine and rain Packing Linear Alkyl Sulphonic Acid | LABSA Liquid Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) package by 200 kg Linear Alkyl Benzene Sulphonic Acid package by 210 kg Linear Alkyl Benzene Sulphonic Acid package by 220 kg net plastic drum. It’s possible packing in pelleting for each 4 LABSA Liquid drums. However according to customer inquiries it is able to offer in Bulk. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid Exporting Destinations: ATDM are exporting Sulphonic Acid to African, European, South American, East Asian countries.ATDM lead to packing and exporting to mention above destinations, under Iran authorization by the best Iranian LABSA Liquid raw materials in accordance with standard. If you want the updated price for LABSA Liquid or Linear Alkyl Benzene Sulphonic acid and knowing more about further details, please contact us. Advantage of Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid: LABSA Liquid Excellent solubility even at low temperatures LABSA Liquid has high power of foam LABSA Liquid is a biodegradable. Linear Alkyl Benzene Sulphonic Acid application Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is used in produce cleansers, light detergent, hard detergent, Liquid Soap, Cleaning powder, Scouring Bar, Oil soaps etc. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is used in produce various detergents and emulsifiers. It is used to increase the surface area of distempers Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is used in produce cleaner of textile industry such as washing powder. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is used in produce industrial electronic, leather industry. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is used in produce paper-making industry. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid can be used in produce detergent of dishware. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is used to produce Linear Alkyl Benzene Sulphonic Acid sodium. Warning LABSA Liquid, Linear Alkyl Benzene Sulphonic Acid LABSA Liquid, Linear Alkyl Benzene Sulphonic acid is capable of causing eye, skin and lung irritation as well as burns in extreme cases. Thus, occupational exposure limits should be implemented for safe industrial practices. When you work with sulfonic acid, LABSA Liquid, you must be caring you. Same as workplace that make use of Linear Alkyl Benzene sulphonic acid, LABSA Liquid should have enclosed operations with the use of local ventilation or exhaust to release the chemicals. You should be attention to warning information at the work area to communicate all the safety about this corrosive element. Linear Alkyl Benzene Sulphonic Acid Product description CAS No.: 27176-87-0 Synonyms: Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA Liquid; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; n-Dodecylbenzene Sulfonic Acid Linear Alkyl Benzene Sulphonic Acid is a synthetic surfactant with a wide range of applications like as a coupling agent, as an emulsifier and in the production of household detergents. LABSA Liquid 96% Linear Alkyl Benzene Sulphonic Acid DBSA For Laundry soap detergent Description: it is a kind of weak organic acid and easy to dissolve in water. Widely used in washing powder, civil detergent cleanser and industrial detergents 96% active content,brown liquid ,must be neutralized by hydroxyl sodium when use it . Feature: Product name: Linear Alkyl Benzene Sulphonic Acid Other name: LAS,LABSA Liquid,Dodecyl Benzenesulfonic Acid Molecular Formula:C18H30O3S CAS No.: 85536-14-7 HS Code: 34021100 Molecular weight: 326.49 Apparence:brown liquid Synonyms: Linear alkyl benzene Sulphonic Acid (LABSA Liquid) SYNONYMS: Dodecylbenzene Sulfonic Acid (Strait Chain); LAS; LABSA Liquid; Laurylbenzenesulfonic Acid; Laurylbenzenesulfonate; N-Dodecylbenzene Sulfonic Acid; Alkylbenzene sulphonate, sodium salt; Linear Alkyl benzene Sulphonic Acid; Linear alkyl benzene Sulphonic Acid is household detergents including laundry powders, laundry liquids, dishwashing liquids and other household cleaners. Industrial applications of wetting agent, emulsifier for agricultural herbicides and in polymerization Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 Detergent Chemical: Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 / Application [1] Used as raw material for washing powder, laundry detergent and industrial detergent. [2] can be used as a curing catalyst for amino baking varnish, used to prepare various liquid and solid detergents. [3] It is used for the production of linear alkylbenzene sulfonate sodium salt, ammonium salt and ethanolamine salt. It is the main raw material for the production of detergents, household liquid detergents, industrial detergents and other common detergents. Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 Synonyms: Linear Alkyl benzene Sulphonic Acid; LABSA Liquid;DBSA; Molecular Formula: C18H30O3S Type: Detergent chemical material Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 / Properties LABSA Liquid has the action of detergency, moistening, foaming, emulsion. dispersionand brown viscous fluid in appearance with acidity. it is nonflammable. quickly ,the product has strong absorbency. it would be unclear viscous liquid after absorbed water. Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 / Specification Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 / Application [1] Used as raw material for washing powder, laundry detergent and industrial detergent. [2] can be used as a curing catalyst for amino baking varnish, used to prepare various liquid and solid detergents. [3] It is used for the production of linear alkylbenzene sulfonate sodium salt, ammonium salt and ethanolamine salt. It is the main raw material for the production of detergents, household liquid detergents, industrial detergents and other common detergents. Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 / Packing Packed in plastic drums netted 200 kgs,16 mt / 20 fcl Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid) 96% CAS No. 27176-87-0 Hot Tags: linear alkyl benzene sulphonic acid (LABSA Liquid) 96% CAS No. 27176-87-0, China, suppliers, manufacturers, factory, price, for sale, free sample ARTICLES / LINEAR ALKYL BENZENE SULPHONIC ACID LABSA Liquid | MSDS | APPLICATIONS. Uses advised against Food, drug, pesticide or biocidal product use. 69669-44-9 C10-14 Alkyl deriv benzene sulfonic acid, sodium salt 85117-50-6 C10-14 Monoalkylbenzene sulfonic acid, sodium salt 90194-45-9 C10-13 Alkyl deriv benzene sulfonic acid, sodium salt 127184-52-5 4-C10-13-sec Alkyl deriv. Details of the supplier of the safety data sheet Emergency Telephone Number For information … III. The LABSA Liquid market is driven by the markets … : AC325900000; AC325900010; AC325905000 CAS-No 85536-14-7 Synonyms Mostly dodecylbenzene sulfonic acid. First Aid Measures Inhalation: Move to fresh air. Linear Alkyl Benzene Sulphonic Acid, LABSA Liquid is a largest volume surfactant because of its low cost, good performance; environmental friendliness .For the production of Linear Alkyl Benzene sulphonic acid, LABSA Liquid, alkaline benzene linear sulfation is usually used. CAS N. EC N. SYMBOL Common Name Linear Alkyl Benzene Sulphonic Acid CAS Number Mixture COMPONENT CAS NUMBER CONCENTRATION Benzenesulfonic Acid, C10-16 alkyl Derivatives 68584-22-5 90 – 100% Sulfuric Acid (Byproduct) 7664-93-9 < 1.5% Benzene, C10-16 alkyl Derivatives 68648-87-3 < 1.5% Sulfur Dioxide 7446-09-5 < 0.1% Section 4. We have a combined production capacity of 80000 MT LABSA Liquid per Annum. CHEMICAL NAME : Linear Alkyl Benzene Sulphonic Acid CHEMICAL FORMULA : C6H4 (SO3H) (CS2)10CS3 CAS NUMBER : 27176-87-0 EINECS NUMBER : 248-289-4 EC NUMBER : Not Classified. LINEAR ALKYL BENZENE SULPHONIC ACID. Recommended Use Laboratory chemicals. Linear alkylbenzene sulfonate (LABSA Liquid), the world’s largest-volume synthetic surfactant, which includes the various salts of sulfonated alkylbenzenes, is widely used in household detergents as well as in numerous industrial applications. HAZARDOUS IMPURITIES NAME CONCENTR. Major portion of our production … Linear alkyl benzene sulphonic acid (LABSA Liquid) is prepared commercially by sulfonating linear alkylbenzene (LAB). Its components: linear alkyl benzene Sulphonic Acid, oxygen, sulfur and citric acid. Linear alkyl benzene sulphonic acid is prepared commercially by just sulfonating linear alkylbenzene (LABSA Liquid).Linear alkyl benzene sulphonic acid which is mainly called (LABSA Liquid), the worlds largest volume synthetic surfactant, which includes the various salts of sulfonated alkylbenzenes, which is widely used in household detergents as well as in numerous industrial application. We, New India Detergents Ltd. Group of Companies are engaged in manufacturing of Linear Alkyl Benzene Sulphonic Acid (LABSA Liquid 90% ) since 20 years and have grown to be a leader in its area of operations, adhering to the quality standards and catering to the domestic & global markets. LABSA Liquid . Product Name Dodecylbenzene sulfonic acid, mixture of C10-C13 isomers Cat No. benzene sulfonic acid, sodium salt Category Name Linear Alkylbenzene Sulfonate (LABSA Liquid) Structural Formula Call a … INTRODUCTION: This project profile in detail foresees setting up of unit to produce ACID SLURRY LABSA Liquid have been the major surfactant used in detergents for more than thirty years and continues to represent a substantial portion of the surfactants market today. Supporting this history of safe usage is a large archive of environmental research that has been conducted on LABSA Liquid. This environmental research, performed by top environmental scientists and research agencies, has investigated virtually every part of the environment that could have been exposed to LABSA Liquid. The studies have repeatedly proven LABSA
LACTAMIDE
LACTAMIDE MEA, N° CAS : 5422-34-4, Nom INCI : LACTAMIDE MEA. Nom chimique : N-2-hydroxyethyllactamide. N° EINECS/ELINCS : 226-546-1. Classification : MEA Ses fonctions (INCI) : Antistatique : Réduit l'électricité statique en neutralisant la charge électrique sur une surface Conditionneur capillaire : Laisse les cheveux faciles à coiffer, souples, doux et brillants et / ou confèrent volume, légèreté et brillance Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau Agent d'entretien de la peau : Maintient la peau en bon état
LACTAMIDE MEA
BUTYL LACTATE, N° CAS : 138-22-7, Nom INCI : BUTYL LACTATE, Nom chimique : Propanoic acid, 2-hydroxy-, butyl ester, N° EINECS/ELINCS : 205-316-4; Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Solvant : Dissout d'autres substances. Noms français :HYDROXY-2 PROPANOATE DE BUTYLE NORMAL; Lactate de butyle normal; N-BUTYL 2-HYDROXYPROPANOATE; PROPANOIC ACID, 2-HYDROXY, BUTYL ESTER. Noms anglais : BUTYL LACTATE; BUTYL LACTATE (NORMAL-); n-Butyl lactate; Utilisation: Solvant de laques, solvant d'encres d'imprimerie. 2-Hydroxypropanoic acid butyl ester; Butyl alpha-hydroxypropionate; Butyl lactate; Butyl lactate (natural); Butylester kyseliny mlecne; Lactic acid, butyl ester ; n-Butyl lactate; Propanoic acid, 2-hydroxy-, butyl ester. : butyl 2-hydroxypropanoate. Hydroxypropanoic acid, butylester