Acetoacetic ester; EAA; Ethyl beta-ketobutyrate; Acetoacetic ester, diacetic ether; Ethyl 3-oxobutanoate; Ethyl acetoacetate; Ethyl acetylacetate; 3-Oxobutanoic acid ethyl ester; Ethyl 3-ketobutyrate; Ethyl acetylacetate; Ethyl acetonecarboxylate; Ethylacetoacetat (German); Acetoacetato de metilo (Spanish); Acétoacétate de méthyle (French); cas no : 141-97-9

ETHYLENE DIOLEAMIDE, N° CAS : 110-31-6. Nom INCI : ETHYLENE DIOLEAMIDE. Nom chimique : N,N'-Ethane-1,2-diylbisoleamide. N° EINECS/ELINCS : 203-756-1. Ses fonctions (INCI) Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

ETHYLENE DISTEARAMIDE, N° CAS : 110-30-5. Nom INCI : ETHYLENE DISTEARAMIDE. Nom chimique : N,N'-Ethylenedi(stearamide). N° EINECS/ELINCS : 203-755-6/931-299-4. Ses fonctions (INCI) : Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques

ETHYLENE DODECANEDIOATE, N° CAS : 54982-83-1, Nom INCI : ETHYLENE DODECANEDIOATE, Nom chimique : 1,4-Dioxacyclohexadecane-5,16-Dione, N° EINECS/ELINCS : 259-423-6, Ses fonctions (INCI). Agent masquant : Réduit ou inhibe l'odeur ou le goût de base du produit. Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques

Ethylene Distearamide is a diamide.
Ethylene Distearamide (C38H76N2O2) is an organic compound otherwise called EBS.
Ethylene Distearamide is a waxy white solid that is also found in powder or bead form.


CAS Number: 110-30-5
EC Number: 203-755-6
MDL number: MFCD00059224
Molecular Formula: C38H76N2O2


Ethylene Distearamide (C38H76N2O2) is an organic compound otherwise called EBS.
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide is a synthetic wax with high melting point.
Ethylene Distearamide is a hard and brittle white high melting point wax.
Ethylene Distearamide is derived from the reaction of ethylenediamine and stearin.


Ethylene Distearamide is a waxy white solid that is also found in powder or bead form.
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide also functions as an external lubricant for PVC and a process aid for polyolefins.
Ethylene Distearamide is suitable for composites, styrenics and rubber.
Ethylene Distearamide has a shelf life of 365 days.


Ethylene Distearamide is also available in bead form.
Ethylene Distearamide is a secondary bis-amide additive.
Ethylene Distearamide has good anti-blocking properties in polyolefins.


Ethylene Distearamide powder is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.
Ethylene Distearamide has no influence on the transparency of the Polymers.
Ethylene Distearamide is a widely used lubricant, high melting wax and white/yellow liquid.


Ethylene Distearamide is white or slight yellow powder or granule
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is an amide wax.


Ethylene Distearamide has good compatibility applied in most of the plastics with the function of lubricating, dispersing, fusing, breaking, smoothing, anti-stick and anti-static.
Ethylene Distearamide is a white solid of low toxicity that provides a slippery coating for a variety of applications.


Ethylene Distearamide has excellent connectivity and dispersion on pigments and buffers.
Ethylene Distearamide is an organic compound with the formula (CH2NHC(O)C17H35)2.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide is white spherical particle, non-toxic and no side effect on humans.
Ethylene Distearamide is insoluble in most organic solvents at room temperature.
Ethylene Distearamide is stable to acid, alkali and water medium.


Ethylene Distearamide is soluble in hot chlorinated hydrocarbons and aromatic hydrocarbon solvents.
Ethylene Distearamide is insoluble in organic solvents and water.
Ethylene Distearamide is soluble in high boiling solvents such as xylene, chloroform and butanol.


The flash point of Ethylene Distearamide is below 285°C and the density is 0.98 (25°C).
Synthhetic wax having high melting point, Ethylene Distearamide has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.


Ethylene Distearamide is a synthetic wax made by combining two stearic acid molecules with one molecule of ethylenediamine.
Together the resulting Ethylene Distearamide is a white, waxy solid that is sold as a powder in various mesh sizes.
Ethylene Distearamide is an amide wax of type N,N-bis-stearyl ethylenediamine with particularly good thermostability.


Ethylene Distearamide is an amide wax of type Ethylene Distearamide.
Ethylene Distearamide acts as a slip and anti-block additive.
Ethylene Distearamide is based on a non-vegetable origin, secondary bis-amide.


Ethylene Distearamide is non-toxic, has no smell and is not soluble in water at room temperature. It has solubility in chlorinated or aromatic solvents.
The primary use for Ethylene Distearamide is as a release agent for PVC (poly-vinyl chloride) extrusion.
Ethylene Distearamide is compatible with styrene & styrenic copolymer, PVC, PO and PS.


Ethylene Distearamide exhibits good thermostability and excellent slip properties.
Ethylene Distearamide acts as both an internal and external lubricant to enhance malleability of the PVC resin.
Ethylene Distearamide is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.


Ethylene Distearamide will inherently lower the viscosity of the polymer resin and can decrease friction and abrasion of the polymer surface.
The recommended dosage levels are 500-2000 ppm in films and 0.2-1.0% in molding applications.
Ethylene Distearamide is EU 10/2011, FDA (175.105) and FDA (175.300) approved.


Ethylene Distearamide is ethylene-bis-stearamide of non-vegetable origin.
Ethylene Distearamide is a secondary bis amide effective as an anti-block agent and process aid for polyolefins.
Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.


Ethylene Distearamide is a white solid that provides a slippery coating for a variety of applications.
Ethylene Distearamide is also a dispersal agent and helps contribute to color uniformity and stability of the resulting extruded PVC product.
Adding Ethylene Distearamide to your thermoforming process will increase productivity by reducing shear stress.


Ethylene Distearamide is a white solid of low toxicity that provides a slippery coating for a variety of applications.
The overall product, Ethylene Distearamide, has a high gloss finish, smooth surface and increased tensile strength.
Overall, Ethylene Distearamide is an extremely cost effective and safe additive to use in the thermoplastic industry.


Ethylene Distearamide is used Chelated fertilizer, oil field chemicals.
Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.
Ethylene Distearamide's industrial products are slightly yellow particles or white powder, non-toxic, and have no side effects on the human body.


Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.
Ethylene Distearamide is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
Ethylene Distearamide is derived from stearic acid and ethylenediamine.


Ethylene Distearamide is derived from the reaction of ethylenediamine and stearic acid.
Ethylene Distearamide by MLA Group has low acid value ( free fatty acid ), high melting point, and excellent white colour, and high purity.
Ethylene Distearamide offers mold release benefits in polyamides (nylon).


Ethylene Distearamide disperses evenly through the polymer in the melt phase, and migrates to the surface where it forms a thin lubricating layer that reduces coefficient of friction between surfaces and reduces unwanted adhesion.
Ethylene Distearamide has some functions as internal and external lubricant, releasing and dispersion agent of pigment for the most thermosetting and thermoplastic resins.


Ethylene Distearamide is a hard and brittle white high melting point wax, it's industrial products are slightly yellow fine particles, insoluble in most solvents at room temperature, stable to acids and bases, and aqueous media, soluble in hot chlorinated hydrocarbons and aromatic hydrocarbons solvents, it’s powder slippery feeling strong, above 80 ℃ to water with wettability of the compound.



USES and APPLICATIONS of ETHYLENE DISTEARAMIDE:
Ethylene Distearamide is used as a processing aid, dispersing agent and release agent.
In PVC applications and masterbatches the Ethylene Distearamide is used as an internal and external lubricant.
Ethylene Distearamide is used in the following areas: formulation of mixtures and/or re-packaging.


Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Ethylene Distearamide additive has high melting point and temperature stability.
This makes Ethylene Distearamide particularly suitable for the bitumen industry.
Ethylene Distearamide is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.


Because of its excellent lubricating properties Ethylene Distearamide is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.
Ethylene Distearamide can be found in industrial use: in processing aids at industrial sites, formulation in materials and as processing aid.


Ethylene Distearamide is used in the following products: lubricants and greases, polymers, washing & cleaning products, inks and toners, metal working fluids, textile treatment products and dyes and coating products.
Ethylene Distearamide is paraffin-free.


Ethylene Distearamide is used in powder metallurgy.
Ethylene Distearamide, a new plastic lubricant developed in recent years, is widely used in the molding and processing of PVC products, ABS, high impact polystyrene, polyolefin, rubber and plastic products.


Ethylene Distearamide can be found in: outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).
Ethylene Distearamide provides optimized bitumen stability and is suitable for polymer-stabilized bitumens.


Due to Ethylene Distearamide's high melting point, the additive offers good thermal stability.
Ethylene Distearamide is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene Distearamide is used as processing aid for resins and polymers and as defoaming agent.


Useful as defoamer for paper making and textile processing .
Ethylene Distearamide is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylene Distearamide is used to prevent the adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Ethylene Distearamide is used Raw materials, Ethylenediamine Trap Stearic acid, Preparation Products, defoaming agent OTD.


Ethylene Distearamide is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Ethylene Distearamide is used in powder metallurgy.
Ethylene Distearamide is used as additive Ethylene Distearamide can be incorporated directly into polymers to prevent any unwanted adhesion.


Ethylene Distearamide can be found in products with material based on: rubber (e.g. tyres, shoes, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).
Ethylene Distearamide has proven mould release action in polyamides, and is a lubricant for PVC.
Ethylene Distearamide is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes


Ethylene Distearamide can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.
Ethylene Distearamide is used to lower the processing temperature and viscosity.


Ethylene Distearamide can be found in industrial use: formulation of mixtures, formulation in materials, as processing aid, manufacturing of the substance and in processing aids at industrial sites.
As a degassing agent it is used in powder coatings.


Ethylene Distearamide can be found in industrial use: in processing aids at industrial sites, as processing aid, in the production of articles, formulation in materials, formulation of mixtures and of substances in closed systems with minimal release.
Ethylene Distearamide is used as processing aid for resins and polymers and as defoaming agent.


Ethylene Distearamide is used for the manufacture of: rubber products and plastic products.
Ethylene Distearamide is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Ethylene Distearamide is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
As Ethylene Distearamide has good wearable performance and smoothing performance, fits for improving polishing performance of lacquer, air release of surface with holes, Ethylene Distearamide is also well used as dulling agent for polishing furniture and printing ink.


Ethylene Distearamide is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Ethylene Distearamide is compared with traditional lubricants such as paraffin wax, polyethylene wax, stearate, etc.
Cosmetic Uses of Ethylene Distearamide: viscosity controlling agents


Ethylene Distearamide is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Ethylene Distearamide is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.


Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide is used as lubricant with good inner or outer lubricant action and has good coordination when used together with other lubricants as high grade alcohols, aliphatic acid esters, calcium stearate and paraffin.


Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


Ethylene Distearamide not only has good external lubrication effect, but also has good internal lubrication effect, which improves the fluidity and demoulding property of melted plastic in plastic molding process, thus improving the yield of plastic processing, reducing energy consumption, and making the product obtain high surface smoothness and smoothness.


Ethylene Distearamide can help to increase the melting point of petroleum products; lubricant and corrosive agent of metal wire drawing.
Ethylene Distearamide is used in all types of industry, especially in the manufacture of plastics and paints, as a dispersing or lubricating agent to facilitate and stabilize the dispersion of materials in mixtures, to reduce friction and abrasion of the surface of polymers, or to contribute to color stability.


Ethylene Distearamide is added in the coating production to increase the uniform dispersion of pigment and filler, improve the surface leveling property of baking paint, prevent the stripping off of paint film and improve water-proof and acid-resistant and alkali-resistant property.
Other Industrial Uses of Ethylene Distearamide: Modifier Used in Asphalt Production to Lower the Temperature at Which the Asphalt Will Soften.


Ethylene Distearamide is a bis-amide anti-blocking additive used to prevent blocking and as anti-tack of adhesives.
Ethylene Distearamide is used in the following products: washing & cleaning products, lubricants and greases, coating products, inks and toners and polishes and waxes.


Ethylene Distearamide is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.
Ethylene Distearamide is non-toxic and can be dispersed evenly through the polymer in the melt phase.


Ethylene Distearamide is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Because of it's excellent lubricating properties, Ethylene Distearamide is widely used internally and/or externally in most plastics such as ABS, PS, PP etc.


Ethylene Distearamide is used to prevent adhesive granulate from sticking together during storage, or to prevent adhesive film layers to attract dirt or stick together before application by reactivation or melting.
Slip- and anti-blocking agent for polyolefins and PVC, especially for film applications and also lubricant for wood plastic composites and plastics.


Ethylene Distearamide is useed Anti-Blocking Agent, Release Agent, Slip Agent, Flow Promoter, and Hot-Melt Adhesive.
In nitrocellulose lacquers, Ethylene Distearamide can bring about the flatting action.
Experience has shown that simple manual mixing prior to processing will normally give an acceptable dispersion though, mechanical means are preferred.


Ethylene Distearamide is used as lubricant in powder metallurgy (PM) steels to reduce the inter-particle and die-wall friction during pressing and hence improve powder compressibility and ejection of the component from the compaction tool.
Ethylene Distearamide is a lubricant widely used in molding and processing of PVC, ABS, high-impact polystyrene, polyolefin, rubber and plastic products.


Ethylene Distearamide is also used in processing industries, for example in the paper industry and the powder metallurgy sector, as a release agent, as an antistatic agent and an anti-foam agent for the production of thermoplastics , cables and paper.
Ethylene Distearamide is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Ethylene Distearamide is high melting wax and white/yellow liquid.
Ethylene Distearamide is used in the following products: polymers, lubricants and greases, metal working fluids, pharmaceuticals and cosmetics and personal care products.


In synthetic fiber industry, Ethylene Distearamide can improve the heat-resistant, weather-resistant property of polyester and polyamide and bring about certain antistatic effects.
Ethylene Distearamide is traditionally used as lubricant and binder for cold compaction of powdered metal parts.


Compared with traditional lubricants such as paraffin wax, polyethylene wax and stearate, Ethylene Distearamide not only has good external lubricity, but also has good internal compatibility, applied in most plastics with good function lubricating, dispersing, fusing, breaking, smoothing, anti-stick and anti-static properties.


Ethylene Distearamide is used in the following areas: formulation of mixtures and/or re-packaging and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylene Distearamide is used for the manufacture of: rubber products, textile, leather or fur, machinery and vehicles and chemicals.


Ethylene Distearamide is used as a processing aid for resins and polymers and as a defoaming agent.
As Ethylene Distearamide has strong cohesions with pigment or other filler, Ethylene Distearamide can improve the dispersion and coupling property of fillers in the polymers to enhance the commercial value of the products.


Ethylene Distearamide is used as defoamer/ anti-foaming agent and coating component of paper for paper-making industry.
Added in the manufacturing process of dope and oil paint to enhance salt mist and dampproof effect and to improve performance of paint remover.
Ethylene Distearamide is used in powder metallurgy.


Ethylene Distearamide is used in various industries as internal/external lubricant, mold release agent, dispersant and slip- and anti-blocking-agent.
Ethylene Distearamide improves the kneading, processing and vulcanization performance of rubber grains in the processing of rubber.
Ethylene Distearamide derived from stearic acid with ethylene diamine is a synthetic was used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability.


Ethylene Distearamide is also used as release agents, antistatic agents, and antifoaming agents.
Ethylene Distearamide can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.


Ethylene Distearamide is used Lubricant in powder metal molding, rubber, adhesives, coatings, wire drawing, wood plastic composite, Defoamer in paper, Lubricant for Polyacetals, Water repellent for paper, Intermediate for defoamers, and Delustering agent for furniture finishes and printing inks.
Ethylene Distearamide has excellent connectivity and dispersion on pigments and buffers.


Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene Distearamide is used in the following areas: formulation of mixtures and/or re-packaging.


Ethylene Distearamide is used for the manufacture of: rubber products and plastic products.
Ethylene Distearamide can be found in: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).


Ethylene Distearamide is soluble in high boiling solvents such as xylene, chloroform and butanol.
Ethylene Distearamide is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.
Ethylene Distearamide is also used as a release agents, antistats, and antifoaming agent.


Ethylene Distearamide is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.
Ethylene Distearamide provides typical slip and anti blocking characteristics to all polymers.


Ethylene Distearamide powder does not affect the transparency of polymers and acts as lubricant in a wide variety of polymers like PVC, PO, PS and engineering plastics.
Ethylene Distearamide is used as Release agent and flow promoter for all engineering resins, Styrenics and their copolymers


Ethylene Distearamide is used Dispersing agent for masterbatch applications, preferably for engineering resins and PVC, and Modifier in textile auxiliaries.
An addition of 0.5-1 % of Ethylene Distearamide can not only prevent the occurrence of air bubbles but also make the plastic bags be slippery so as to be opened easily.


Ethylene Distearamide can remarkably enhance the heat-resistant and weather-resistant properties while coordinating with chief stabilizer in formulation of inorganic filler for PVC and polyolefin.
Ethylene Distearamide is used as anti-adhesive agent for various polymer film or sheets.


Ethylene Distearamide is used as nucleation transparency agent to reduce the nucleating time in compounds such as polyolefins, polyformaldehyde and polyamide, promote the structure of resin to become fine, thus improve the mechanical property and transparency of the products.
Ethylene Distearamide is used as processing auxiliary of rubber. Besides the lubricant demoulding property and modifying performance of filler surface,

Ethylene Distearamide can raise the surface fineness of rubber pipes and rubber plates to act as rubber surface polishing agent.
Ethylene Distearamide is not just for PVC thermoforming, it is suitable as an additive for nearly any thermoplastic manipulation with benefits similar to those described above for the PVC process.


Ethylene Distearamide is used in the spinning of antistatic nylon fiber as additive and also is able to reduce the breaking of yarn.
Ethylene Distearamide can be used with ABS, polystyrene, polyethylene, polypropylene and more.
Ethylene Distearamide is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Ethylene Distearamide migrates to the surface of the polymer where it forms a thin lubricating layer.
Ethylene Distearamide is used in the following products: adhesives and sealants, lubricants and greases, coating products, polishes and waxes and washing & cleaning products.


Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.


In plastic masterbatch applications Ethylene Distearamide reduces the amount of resin/binder necessary which translates to cost savings.
Ethylene Distearamide can help to increase the smoothness and fineness for insulator layer of electric power and cable.
Ethylene Distearamide is added to oil based defoamers to improve foam knock down.


Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide improves flow and has no influence on transparency of polymers.
Ethylene Distearamide acts as a lubricant, release & antiblocking agent for all engineering resins and dispersing agent for masterbatch applications.


Because of it's excellent lubricating properties, Ethylene Distearamide is widely used internally and/or externally in most plastics such as ABS, PS, PP, etc.
Ethylene Distearamide is used as additive Ethylenebisstearamide can be incorporated directly into polymers to prevent any unwanted adhesion.
Ethylene Distearamide can also be a binder in the precise engineering metal part.


Due to it's good dispersing ability and surface migration Ethylene Distearamide can be used in printing inks.
A field of application is the bitumen industry: When used in asphalt binder for road making (asphalt modifiers), Ethylene Distearamide increases its softening point and enhances its visco-elasticity.


Ethylene Distearamide can decrease the viscosity of asphalt and improve it’s softening point and weathering resistance when added to asphalt.
Ethylene Distearamide can also be used as a process aid, for example to improve dispersion of fillers.
Ethylene Distearamide is used as an additive for hot melt adhesives.


Lubrication performance is excellent, anti-calcium salt ability is strong, drag reduction effect is good, used for drilling in saturated brine to reduce power consumption.
Ethylene Distearamide is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits.


Ethylene Distearamide is an internal additive and can be incorporated into resin as supplied or via masterbatch / pre-blend.
Ethylene Distearamide is used for lubricant of plastic and metal molding, adhesion preventives, viscosity modifier, anti-corrosion of wax, water resistance of coating and spray paint.


In the processing of ABS, AS, hard PVC, polyformaldehyde, polycarbonate, polyurethane and phenolformaldehyde resins, Ethylene Distearamide is used as lubricant demoulding agent with a quantity of 0.5~1.5 %.
Ethylene Distearamide will also help with pigment dispersal and give the finished product a more vibrant glossy finish.


Typical addition levels vary depending on polymer and lubrication required.
Ethylene Distearamide acts as a slip and anti-block agent, mold release agent and lubricant for PVC.
Dispersing agent for masterbatch applications, preferably for engineering resins and PVC.


Ethylene Distearamide provides typical slip and anti blocking characteristics to all polymers e.g. in films.
Ethylene Distearamide has proven mold release benefits in nylon and is a lubricant for PVC.
Application of Ethylene Distearamide: Water treatment


Ethylene Distearamide is used as an internal and external slip agent in many thermoplastic and thermosetting plastics, the most representative ones are ABS, PS, ABS, PVC, also used in PE, PP, PVAC, cellulose, Accurate, Nylon, phenolic-Resin, amino plastics.
Ethylene Distearamidehas a good finish and good film release.


As a lubricant of polyformaldehyde, the addition amount is 0.5%, which improves the melt flow rate and the film release, and the whiteness, thermal stability and physical index of polyformaldehyde all reach the superior index.
Chemical fiber: Ethylene Distearamide can improve the heat and weather resistance, fluidity of polyester, polyamide fiber, and give a certain anti-static effect.


Release agent: Phenolic resin for sand casting with Ethylene Distearamide can be used as a release agent.
Powder Coating: Ethylene Distearamide can be used as flow additives for powder coatings.
Hot-Melt Adhesive Applications of Ethylene Distearamide: Release agent and flow promoter for all engineering resins, Styrenics and their copolymers.


Chemical fiber: Ethylene Distearamide can improve heat and weather resistance performance of polyester and polyamide fiber, and has some anti-static effect.
Pigment and filler: Ethylene Distearamide can be used as pigment dispersant of plastic , fiber, such as ABS, PS, polypropylene fibre and PET fiber and other color masterbatch.


Ethylene Distearamide is used as additive EBS can be incorporated directly into polymers to prevent any unwanted adhesion.
Adhesive pellets or film often develop adhesion between the polymer pellets or layers when exposed to elevated temperatures and pressures.


When manufacturing coating and painting, Ethylene Distearamide can improve the effect of salt spray and moistureproof by adding Ethylene Distearamide.
Ethylene Distearamide can help to improve the paint stripper performance of paint when added, and to increase the leveling performance of baking enamel varnish.


-Uses & Applications
*Flow Enhancer in Powder Coating Additives
*Metal Working Fluids
*Friction Reducing Lubricant in Wire-Drawing
*Plastics
*Internal and External Lubricant, Pigment Stabilizer and Dispersant in the Processing of all Types of Plastics
*Imparts a Smooth Gloss Finish to Rigid PVC
*Improves the General Surface Appearance of Most Plastics.
*The Multiple Functions of EBS in Plastics Production Improve Processing Time and Reduce Processing Costs
*Rubber
*Release Agent and Additive to the Surface Finishing in the Production of Rubber
*Textiles and Paper
*Anti-Static Agent and Anti-Foaming Agent in Paper and Textile


-Paint, Ink:
*Adding 0.5~2% Ethylene Distearamide can improve the effect of salt spray and moisture resistance in the manufacture of paint and lacquer.
*Adding Ethylene Distearamide in the paint can improve the performance of the paint stripper and can improve the leveling of the baked enamel surface.
*Ethylene Distearamide can be used as a matting agent in furniture polishing agents and printing ink.
*After micronization (particle size: d50 about 6μ, d 90 about 12μ), Ethylene Distearamide has excellent anti-abrasion and smoothness and can be used in lacquer systems to improve polishability and degassing on a porous surface.


-Applications of Ethylene Distearamide:
*Adhesives & sealants
*Composites
*Inks


-Mode of action:
Ethylene Distearamide can be dispersed evenly through the polymer in the melt phase.
Ethylene Distearamide migrates to the surface of the polymer where it forms a thin lubricating layer.
This layer reduces the coefficient of friction between surfaces and prevents any unwanted adhesion.


-Other uses of Ethylene Distearamide:
*Melting point rising agent for petroleum products
*Lubricant and anti-corrosion agent for metal drawing
*Potting material for electrical components; defoaming agent and paper coating ingredient for paper industry
*Ethylene Distearamide is used as a defoaming agent and permanent water pulling agent for dyeing works in textile dyeing and finishing
*Adding this product in asphalt can reduce the viscosity of asphalt and improve the softening point, water-resistance and weather resistance of asphalt.


-Pigment, filler dispersant:
*Ethylene Distearamide is used as a pigment dispersant for plastic.
*Pigment dispersant for chemical fiber masterbatches, such as ABS, PS, polypropylene, polyester masterbatches.
*Ethylene Distearamide can also be used as diffusion powder for plastic color matching.
*Depending on the amount of pigment and filler added, the addition amount is 0.5~5%.


-Consumer Goods:
*Appliances & Electronics
*Adhesives & Sealants: Industrial & *Assembly Adhesives
*Electronics Adhesives
*Industrial Manufacturing
*Healthcare & Pharma — Medical
*Medical Tapes & Adhesives
*Electrical & Electronics — Packaging & Assembly
*Adhesives & Sealants
*Adhesive & Sealant Type


-Rubber:
Synthetic resin and rubber will have good anti-adhesive and anti-caking effect by adding Ethylene Distearamide in their emulsion.
Ethylene Distearamide has a good effect to the increase surface gloss when added to rubber products.


-Plastic uses of Ethylene Distearamide:
Lubricants inside or outside many plastics such as ABS, PS, AS, PVC, PE, PP, PVAC, cellulose acetate, nylon, phenolic resin and amino plastics.
Ethylene Distearamide has a good surface quality and demoulding performance.


-Rubber:
Synthetic resins and rubber such as Vinyl, polychloroprene, GRS (SBR) add 1~3% EBS to their emulsions, it has a good anti-viscosity and anti-caking effect, EBS is used in floor mats for automobiles, drainage pipes, and other rubber products to increase the effect of surface gloss.



PROPERTIES OF ETHYLENE DISTEARAMIDE:
– Release agent
– lubricant
– dispersing agent
– Anti-foaming
– Anti-static



BENEFITS of ETHYLENE DISTEARAMIDE:
-Excellent slip and anti-blocking properties when used in PVC, engeneering resins, PO film and compounds
-Good release properties in PVC and thermoplastics
-Improves flow of polymers
-No influence on transparency of polymers
-Wide food approval



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE DISTEARAMIDE:
Appearance: White, waxy crystals
Odor: Odourless
Melting point: 144 to 146 °C (291 to 295 °F; 417 to 419 K)
Flash point: 280 °C (536 °F; 553 K)
Physical state: Beads
Color: white
Odor: odorless
Melting point/range: 144 - 146 °C - lit.
Initial boiling point and boiling range: 260 °C at 1.013 hPa
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Flash point: ca.270 °C - DIN 51758
Autoignition temperature: ca.380 °C at 1.013 hPa - DIN 51794
Decomposition temperature: > 200 °C -
pH: No data available
Viscosity Viscosity, kinematic: No data available
Viscosity, dynamic: ca.10 mPa.s at 150 °C
Water solubility at 20 °C: insoluble

Partition coefficient: n-octanol/water log Pow: 13,98 at 25 °C
Vapor pressure: Not applicable
Density: 1 g/cm3 at 20 °C
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 720.34 °C. @ 760.00 mm Hg (est)
Flash Point: 213.00 °F. TCC ( 100.70 °C. ) (est)
logP (o/w): 14.787 (est)
Soluble in: water, 2.049e-010 mg/L @ 25 °C (est)

Molecular Weight: 593.0
XLogP3-AA: 15.7
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 35
Exact Mass: 592.59067967
Monoisotopic Mass: 592.59067967
Topological Polar Surface Area: 58.2 Ų
Heavy Atom Count: 42
Formal Charge: 0
Complexity: 503
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
vapor pressure: 0.000023 Pa (20 °C)
refractive index: 1.4670 (estimate)
Flash point: 280℃
storage temp.: 2-8°C
solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
pka: 15.53±0.46(Predicted)
form: beads
Appearance: Powdery
Smell: No smell
Color (Gardner): ≤3#
Melting Point (℃): 141.5-146.5
Acid Value (mgKOH/g): ≤7.50
Amine value (mgKOH/g): ≤2.50
Moisture (wt%): ≤0.30
Mechanical impurity: Φ0.1-0.2mm(individual/10g)



FIRST AID MEASURES of ETHYLENE DISTEARAMIDE:
-Description of first-aid measures:
*After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*After swallowing:
Make victim drink water (two glasses at most).
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE DISTEARAMIDE:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up dry.
Dispose of properly.



FIRE FIGHTING MEASURES of ETHYLENE DISTEARAMIDE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE DISTEARAMIDE:
-Control parameters
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE DISTEARAMIDE:
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ETHYLENE DISTEARAMIDE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .



SYNONYMS:
1,2-BIS(OCTADECANAMIDO)ETHANE
1,2-ETHYLENEBIS(STEARAMIDE)
ABRIL WAX 10DS
ACRAWAX C
ADVAWAX
ARMOWAX EBS-P
BIS(STEAROYL)ETHYLENEDIAMIDE
CARLISLE WAX 280
CHEMETRON 100
ETHYLENE BIS STEARAMIDE
ETHYLENE DISTEARAMIDE
ETHYLENE DISTEARAMIDE [INCI]
ETHYLENEBIS (STEARAMIDE )
ETHYLENEBIS(STEARIC ACID AMIDE)
ETHYLENEDIAMINE BIS(STEARAMIDE)
KEMAMIDE W 40
LIPOWAX C
LUBROL EA
MICROTOMIC 280
N,N-ethylenedi(stearamide)
1,2-distearamidoethane
N,N-Ethylenebisoctadecanamide
N,N'-ethylene bis-stearamide
N,N'-ethane-1,2-diyldioctadecanamide
2,5-dihexadecylhexanediamide
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
N,N′-Ethylenedi(stearamide)
Ethylene distearylamide
N,N′-(Ethane-1,2-diyl)di(octadecanamide)
ETHYLENE-BIS-STEARAMIDE
waxc
EBSA
advawax
acrawaxc
acrowaxc
lubrolea
5-AC-13C4
acrawaxct
110-30-5
N,N'-Ethylenebis(stearamide)
Plastflow
Ethylene distearamide
N,N'-(Ethane-1,2-diyl)distearamide
Advawax
Acrowax C
Acrawax CT
Lubrol EA
Ethylenedistearamide
Microtomic 280
Advawachs 280
Ethylenebis(stearylamide)
Abril wax 10DS
Carlisle 280
Nopcowax 22-DS
Ethylenebisstearoamide
Advawax 275
Advawax 280
Carlisle Wax 280
Armowax ebs-P
Ethylenebis(stearamide)
Octadecanamide, N,N'-1,2-ethanediylbis-
N,N'-Ethylenebisoctadecanamide
1,2-Bis(octadecanamido)ethane
Chemetron 100
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-Ethylenedistearamide
Ethylenediamine steardiamide
Ethylenediamine bisstearamide
N,N'-Distearoylethylenediamine
Ethylenebisstearamide
N,N'-Ethylenebisstearamide
NN'-Ethylenebis(stearamide)
Stearic acid, ethylenediamine diamide
Ethylenebisoctadecanamide
Octadecanamide, N,N'-ethylenebis-
UNII-603RP8TB9A
N-[2-(octadecanoylamino)ethyl]octadecanamide
N,N-Ethylenebis(stearamide)
603RP8TB9A
N,N'-ethane-1,2-diyldioctadecanamide
Acrawax C
Kemamide W 40
N,N'-Ethylenedi(stearamide)
WAX C
N,N-Ethylenebisstearamide
CCRIS 2293
ethylene bisstearamide
HSDB 5398
Ethylene bis stearamide
Ethylene bis(stearamide)
EINECS 203-755-6
NSC 83613
N,N'-Ethylene bisstearamide
AI3-08515
N,N'-ethylene-bis-stearic amide
Abluwax EBS
Armowax EBS
Dorset WAX
C38H76N2O2
N,N'-ethylenebis
Glycowax 765
Kemamide W-39
Kemamide W-40
N,N'-1,2-Ethanediylbisoctadecanamide
Uniwax 1760
EC 203-755-6
Ethylene Bis Stearamide SF
SCHEMBL19975
Octadecanamide,N'-ethylenebis-
DTXSID4026840
NSC83613
MFCD00059224
NSC-83613
ZINC85733714
AKOS015915120
Octadecanamide,N'-1,2-ethanediylbis-
DS-6811
E0243
FT-0629590
V0595
D70357
N,N'-Ethylenebis(stearamide), beads, A802179
Q5404472
W-108690
2,5-dihexadecylhexanediamide
N,N'-(Ethane-1,2-diyl)distearamide
Plastic additive 03, European Pharmacopoeia (EP)
n,n'-ethylenebisoctadecanamide (mixture of fatty acid amides) (consists of c14, c16 and c18)
N,N'-Ethylenedi(stearamide)
1,2-Bis(stearoylamino) ethane
N,N′-1,2-Ethanediylbisoctadecanamide
Ethylene distearylamide
Ethylene bisstearamide
Ethylene distearamide
EBS
1,2- Bis(octadecanamido)ethane
Ethylenebisoctadecanamide
Ethylenebis(stearylamide)
Ethylenediamine bisstearamide
N-[2-(octadecanoylamino)ethyl]octadecanamide
N-(2-stearamidoethyl)stearamide
N,N'-Distearoylethylenediamine
N,N'-ethane-1,2-diyldioctadecanamide
N,N'-Ethylenedistearamide
n,n'-Ethylene distearylamide
Octadecanamide
N,N'-1,2-ETHANEDIYLBISOCTADECANAMIDE
N,N'-BIS(OCTADECANOYL)ETHYLENEDIAMINE
N,N'-DIST EAROYLETHYLENEDIAMINE
N, N'-ETHYLENE BISSTEARAMIDE
N,N'-ETHYLENE DISTEARYLAMIDE
N,N'-ETHYLENE DISTEARYLAMIDE [HSDB]
N,N'-ETHYLENEBIS(STEARAMIDE)
N,N'-ETHYLENEBIS(STEARIC AMIDE)
N,N'-ETHYLENEDISTEARYLAMIDE
NOPCOWAX 22-DS
NSC-83613
OCTADECANAMIDE, N,N'-1 ,2-ETHANEDIYLBIS-
OCTADECANAMIDE, N,N'-ETHYLENEBIS-
PLASTFLOW
STEARIC ACID, ETHYLENE DIAMINE DIAMIDE
WAX C

Ethylene distearylamide ( EBS) is a synthetic wax that has fatty amide groups that can interact with the surface of a variety of nanoparticles.
Ethylene distearylamide ( EBS) can be used for a wide range of applications such as lubricants, activators and dispersing agents that reduce the friction in the system and increase the rate of processing.
Ethylene distearylamide ( EBS) is an organic compound with the formula (CH2NHC(O)C17H35)2.

CAS: 110-30-5
MF: C38H76N2O2
MW: 593.02
EINECS: 203-755-6

Ethylene distearylamide ( EBS) is a waxy white solid and is also found as powder or beads that is widely used as a form release agent.
Ethylene distearylamide ( EBS) is derived from the reaction of ethylenediamine and stearic acid.
Ethylene distearylamide ( EBS) is a white solid of low toxicity that provides a slippery coating for a variety of applications.

Ethylene distearylamide ( EBS) Chemical Properties
Melting point: 144-146 °C(lit.)
Boiling point: 646.41°C (rough estimate)
Density: 1 g/cm3 (20℃)
Vapor pressure: 0.000023 Pa (20 °C)
Refractive index: 1.4670 (estimate)
Fp: 280℃
Storage temp.: 2-8°C
Solubility: ketones, alcohols and aromatic solvents at their boiling points: soluble
Form: beads
Pka: 15.53±0.46(Predicted)
Water Solubility: 0ng/L at 25℃
InChIKey: RKISUIUJZGSLEV-UHFFFAOYSA-N
LogP: 13.98 at 25℃
CAS DataBase Reference: 110-30-5(CAS DataBase Reference)
EPA Substance Registry System: Ethylene distearylamide ( EBS) (110-30-5)

Uses
Ethylene distearylamide ( EBS) is a bis-amide polymer additive that lowers the temperature at which the asphalt softens.
Ethylene distearylamide ( EBS) is used as processing aid for resins and polymers and as defoaming agent.
Ethylene distearylamide ( EBS) is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
Ethylene distearylamide ( EBS) is a bis-amide polymer additive that lowers the temperature at which the asphalt softens
Ethylene distearylamide ( EBS) is used as processing aid for resins and polymers and as defoaming agent.
Ethylene distearylamide ( EBS) is traditionally used as lubricant and binder for cold compaction of powdered metal parts.
Ethylene distearylamide ( EBS) is an effective lubricant, processing aid, slip additive and pigment dispersant aid for most polymers.
Ethylene distearylamide ( EBS) is an ethylenebisstearamide, specifically developed to afford low, consistent viscosities and superior cost performance in paper pulp defoamer applications.
Useful as defoamer for paper making and textile processing.

Ethylene distearylamide ( EBS) is a synthetic wax used as a dispersing agent or internal/external lubricant for benefits in plastic applications to facilitate and stabilize the dispersion of solid compounding materials to enhance processability, to decrease friction and abrasion of the polymer surface, and to contribute color stability and polymer degradation.
Ethylene distearylamide ( EBS) is also used in process industries as release agent and antistatic agent for the production of thermoplastics,and wiring.
Ethylene distearylamide ( EBS) is used in powder metallurgy.

Synonyms
N,N'-ETHYLENEBISSTEARAMIDE
N,N'-ETHYLENEBISOCTADECANAMIDE
1,2-bis(octadecanamido)ethane
abrilwax10ds
Glyco(R) Asphalt Modifier beads
Acrawax(R) C atomized
N, N` Distearoylethyelendiamine
Acrawax(R) C beads

Ethylene glycol; ethyleneglycol ; Ethanediol; Ethane-1,2-diol; ethanediol; ethylene glycol; GLYCOL, N° CAS : 107-21-1. Nom INCI : GLYCOL. Nom chimique : Ethane-1,2-diol, Ethylene glycol. N° EINECS/ELINCS : 203-473-3. Humectant : Maintient la teneur en eau d'un cosmétique dans son emballage et sur la peau. Solvant : Dissout d'autres substances. Agent de contrôle de la viscosité : Augmente ou diminue la viscosité des cosmétiques. Principaux synonymes. Noms français : 1,2-DIHYDROXYETHANE; 2-HYDROXYETHANOL; ETHANE-1,2-DIOL; ETHANEDIOL-1,2; ETHYLENE ALCOHOL; Glycol d'éthylène; Monoéthylène glycol; Éthylène glycol. Noms anglais : 1,2-Ethanediol; Ethylene glycol. Utilisation: L'éthylène glycol est surtout utilisé : comme composé antigel ou liquide de transfert de chaleur que ce soit pour les radiateurs d'automobiles, les systèmes de refroidissement industriels ou le dégivrage des avions; comme matière première pour la synthèse de fibre de polyester, de films et de résines. Il sert aussi : de solvant dans les peintures au latex, les encres et les adhésifs; d'agent de déshydratation dans le traitement du gaz naturel; dans les formulations de produits pharmaceutiques, comme substitut de la glycérine; dans les préparations de fluides pour transmissions hydrauliques; dans les condensateurs électrolytiques, comme solvant de suspension pour le perborate d'ammonium; pour la fabrication d'explosifs. Translated names 1,2-Etaanidioli; etyleeniglykoli (fi); 1,2-etandiol (no); 1,2-etandiolis (lt); 1,2-ethaandiol (nl); 1,2-ethandiol (da); Etaandiool (et); etandiol (hr); etano-1,2-diol (pl); etanodiol (es); ethan-1,2-diol (cs); Ethandiol (de); ethylenglycol (da); ethylenglykol (cs); etilen glicol (it); etilen-glikol (hr); etilenglicol (es); etilenglikolis (lt); etilenoglicol (pt); etilén-glikol (hu); etilēnglikols (lv); etylenglykol (no); etylénglykol (sk); etán-1,2-diol (hu);Etüleenglükool (et); etāndiols (lv); glicol etilenico (it); glikol (sl); glikol etylenowy (pl); glykol (da); éthylène-glycol (fr); αιθυλενογλυκόλη γλυκόλ (el); етандиол (bg); етилен гликол (bg) CAS names: 1,2-Ethanediol; : 1,2 ethanediol; 1,2-Dihydroxyethane; 1,2-etandiolo; 1,2-ETHANE DIOL; 1,2-ETHANE DIOL1,2-Ethanediol2,2'-oxydiethanolBio MEG.Ethane-1,2-diolEthanediol; Ethylene glycol; ethane-1,2-diolEthanol-1,2-diolEthylene GlycolMEGMono Ethylene Glycol; Monoethylen glycol; MONOETHYLENE GLYCOL; Monoethyleneglycol; Monoethylenglykol; Monothylene Glycol; 1,2-Ethanediol, glycol; 1.2-Ethanediol; 2,2'-oxydiethanol; Bio MEG; CH2OHCH2OH; enthanediolethylene glycole; Ethane-1,2-diol; Ethane -1,2-diol; Ethane 1,2 diol; ethane-1,2-diol/ethylene glycol; ethanediol / ethylene glycol; ethanediol ethylene glycol; Ethanediol; Ethylene glycol; ethane-1,2-diol; ethaneglycol; Ethanol-1,2-diol; Ethylen glycol; ethylene glycol polyester grade;ETHYLENE GLYCOL; 1,2-ethanediol; glycol ; Ethylene glycol; Glycol; Ethylene-glycol; Età-1,2-diol; MEG; mono ethylene glycol; Monoethyleenglycol; Monoethylene glycol; Monoethyleneglycol; Monoethyleneglykol; Monoethylenglycol; Monoethylenglykol; Reaction mass of 64-17-5 and 7732-18-5; Ethanediol Trade names 1,2-Ethylene glycol 1-2 Ethane-diol 2-Hydroxyethanol Adiprene LF 1869A Adiprenes Bio-MEG EG Ethylene alcohol Ethylene dihydrate Ethylene Glycol Antifreeze Grade ETHYLENE GLYCOL INDUSTRIAL GRADE ethylene glycol water blend Ethylene glyvol Ethyleneglykol Fomrez. Glycol Glycol alcohol MEG Fibre MEG Industrial MEG Normal Mono ethyelene Glycol Mono Ethylene Glycol HP Monoethylene Glycol (MEG) MONOETHYLENE GLYCOL, MEG Monoetilenglicol grado fibra Monoetilenglicol grado industrial

1,2-Ethanediol; Ethylene alcohol; Hypodicarbonous acid; Monoethylene glycol; 1,2-Dihydroxyethane cas no: 107-21-1

Glycol Distearate; Ethylene Glycol Dioctadecanoate; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Dioctadecanoate; 1,2-Ethanediyl Octadecanoate CAS NO:627-83-8

DESCRIPTION:

Ethylene Glycol Dihydroxy Dimethyl Ether, a hydrophilic ether,[1] is an electron-donor solvent.
Its toxicity has been assessed.
The effect of complexation of diglyme with lithium trifluoromethanesulfonate on the conformation has been investigated.
Ethylene Glycol Dihydroxy Dimethyl Ether is reported to enhance the ability of KF-MeOH-Al2O3 (potassium fluoride-methanol-alumina) reagent to replace halogen with methoxy groups in 5,8-dihydroxy-2,3-dichloro-1,4-naphthoquinones.


CAS Number: 111-96-6
EC Number: 203-924-4
Molecular Weight: 134.17
Beilstein: 1736101
Linear Formula: (CH3OCH2CH2)2O


SYNONYM(S):
2-Methoxyethyl ether, Bis(2-methoxyethyl) ether, Dimethyldiglycol, ‘Diglyme’,2,2′-Oxybis(ethan-1-ol),2-(2-Hydroxyethoxy)ethan-1-ol,Diethylene glycol,Ethylene diglycol,Diglycol,2,2′-Oxybisethanol,2,2′-Oxydiethanol,3-Oxa-1,5-pentanediol,Dihydroxy diethyl ether,Digenos,Digol,Ethylene glycol bis-mercaptoacetate,diethylene glycol, 2,2'-oxydiethanol, diglycol, diethylenglykol, 2-hydroxyethyl ether, bis 2-hydroxyethyl ether, ethanol, 2,2'-oxybis, 2,2'-oxybisethanol, 2-2-hydroxyethoxy ethanol, digol,(2-hydroxyethoxy) ethan-2-ol,2,2'-oxydiethanol,2,2'-Dihydroxydiethyl ether,2,2'-Oxybis[ethano],2,2'-Oxydiethanol,2,2'-Oxyethanol,2- hydroxyethoxy)ethan- 2-ol,2-(2-Hydroxyethoxy)ethanol,3-Oxapentamethylene-1,5-diol,3-Oxapentane-1,5-diol,(2-hydroxyethyl) ether,Bis(2-hydroxyethyl)ether,Bis(β-hydroxyethyl) ether,DIETHYLENE GLYCOL,111-46-6,2,2'-Oxydiethanol,Diglycol,2,2'-Oxybisethanol,2-(2-Hydroxyethoxy)ethanol,Diethylenglykol,Digol,2-Hydroxyethyl ether,Bis(2-hydroxyethyl) ether,DI(HYDROXYETHYL)ETHER,Ethanol, 2,2'-oxybis-,Digenol,Dicol,Brecolane ndg,Glycol ether,Deactivator E,Dissolvant APV,Ethylene diglycol,2,2'-Oxyethanol,1,5-Dihydroxy-3-oxapentane,Diethyleneglycol,TL4N,3-Oxapentane-1,5-diol,Dihydroxydiethyl ether,2,2'-0xydiethanol,Bis(beta-hydroxyethyl) ether,2,2'-Dihydroxydiethyl ether,Ethanol, 2,2'-oxydi-,2-(2-hydroxyethoxy)ethan-1-ol,2,2'-Dihydroxyethyl ether,beta,beta'-Dihydroxydiethyl ether,Deactivator H,Caswell No. 338A,2,2'-Oxybis(ethan-1-ol),3-Oxapentamethylene-1,5-diol,3-Oxa-1,5-pentanediol,DEG,HSDB 69,NSC 36391,CCRIS 2193,DTXSID8020462,bis(2-hydroxyethyl)ether,EINECS 203-872-2,MFCD00002882,EPA Pesticide Chemical Code 338200,BRN 0969209,CHEBI:46807,AI3-08416,UNII-61BR964293,2,2'-Oxybis[Ethanol],Diethylene Glycol (DEG),NSC-36391,bis-(2-hydroxyethyl)ether,2,2-Di(hydroxyethyl) ether,DTXCID20462,DIETHYLENE GLYCOL ETHER,Bis(.beta.-hydroxyethyl) ether,61BR964293,EC 203-872-2,2,2-OXYDI(ETHAN-1-OL),4-01-00-02390 (Beilstein Handbook Reference),.beta.,.beta.'-Dihydroxydiethyl ether,2,2'-oxybis(ethanol),PEG 400,105400-04-2,149626-00-6,Diethylenglykol [Czech],DIETHYLENE GLYCOL (USP-RS),DIETHYLENE GLYCOL [USP-RS],diethylene-glycol,1,4,10,13-Tetraoxa-7,16-diazacyclooctadecane, 7,16-bis(1-oxodecyl)-,CAS-111-46-6,Chromate(2-), 2-5-(2,5-dichlorophenyl)azo-2-(hydroxy-.kappa.O)phenylmethyleneamino-.kappa.Nbenzoato(,GLYCEROL IMPURITY A (EP IMPURITY),GLYCEROL IMPURITY A [EP IMPURITY],PEG 200,PEG 600,OH-PEG2-OH,diehyleneglycol,Diglykol,Diethyleneglykol,diethyene glycol,2,2'-Oxydiethanol; Etofenamate Imp. F (EP); Etofenamate Impurity F; Glycerol Impurity A,di-ethylene glycol,PEG2000,Diethyl ene glycol,Glicole dietilenico,2-hydroxyethylether,1KA,Diethylenglykol rein,Ethanol,2'-oxydi-,2,2'-Ossidietanolo,2,2'-Oxibesethanol,Ethanol,2'-oxybis-,Glycol hydroxyethyl ether,Diethylene glycol, 99%,3-Oxypentane-1,5-diol,2,2-OXYBISETHANOL,SCHEMBL1462,HO(CH2CH2O)2H,2,2-Oxybis(ethan-1-ol),WLN: Q2O2Q,2-HYDROXYETHOXYETHANOL,MLS001055330,BIDD:ER0301,DIETHYLENE GLYCOL [MI],2-(2-Hydroxy-ethoxy)-ethanol,PEG600,CHEMBL1235226,DIETHYLENE GLYCOL [HSDB],HO(CH2)2O(CH2)2OH,2-(2-hydroxyethoxyl)ethan-1-ol,PEG4000,PEG6000,Diethylene glycol, LR, >=99%,3-OXA-1, 5-PENTANEDIOL,HMS2270G18,NSC32855,NSC32856,NSC35744,NSC35745,NSC35746,NSC36391,PEG35000,Tox21_201616,Tox21_300064,.beta.,.beta.'-Dihydroxyethyl ether,NSC-32855,NSC-32856,NSC-35744,NSC-35745,NSC-35746,STL280303,Diethylene glycol, analytical standard,AKOS000120101,1ST9049,FS-3891,PEG 10,000,PEG 20,000,NCGC00090703-01,NCGC00090703-02,NCGC00090703-03,NCGC00253996-01,NCGC00259165-01,2,2'-Oxydiethanol, 2-Hydroxyethyl ether,BP-20527,BP-22990,BP-23304,BP-25804,BP-25805,BP-31029,BP-31030,BP-31245,Diethylene glycol, ReagentPlus(R), 99%,SMR000112132,DB-092325,CS-0014055,D0495,ETOFENAMATE IMPURITY F [EP IMPURITY],NS00004483,EN300-19318,Diethylene glycol, BioUltra, >=99.0% (GC),Diethylene glycol, SAJ first grade, >=98.0%,E83357,A802367,Diethylene glycol, Vetec(TM) reagent grade, 98%,Q421902,J-002580,F1908-0125,9BAE4479-A6DD-4206-83C1-AB625AB87665,Diethylene glycol, puriss. p.a., >=99.0% (GC),colorless,InChI=1/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H,Diethylene glycol, United States Pharmacopeia (USP) Reference Standard,162662-01-3,31290-76-3,9002-90-8




Ethylene Glycol Dihydroxy Dimethyl Ether appears as a colorless liquid.
Ethylene Glycol Dihydroxy Dimethyl Ether is Denser than water.
Ethylene Glycol Dihydroxy Dimethyl Ether Contact may slightly irritate skin, eyes and mucous membranes.

Ethylene Glycol Dihydroxy Dimethyl Ether May be slightly toxic by ingestion.
Ethylene Glycol Dihydroxy Dimethyl Ether is Used to make other chemicals.
Ethylene Glycol Dihydroxy Dimethyl Ether is a hydroxyether.


APPLICATIONS OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER
Ethylene Glycol Dihydroxy Dimethyl Ether may be used as a solvent to form a solution of sodium pentaphosphacyclopentadienide.


Ethylene Glycol Dihydroxy Dimethyl Ether is an organic compound with the formula (HOCH2CH2)2O.
Ethylene Glycol Dihydroxy Dimethyl Ether is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste.
Ethylene Glycol Dihydroxy Dimethyl Ether is a four carbon dimer of ethylene glycol.


Ethylene Glycol Dihydroxy Dimethyl Ether is miscible in water, alcohol, ether, acetone, and ethylene glycol.[3]
Ethylene Glycol Dihydroxy Dimethyl Ether is a widely used solvent.[4]
Ethylene Glycol Dihydroxy Dimethyl Ether can be a normal ingredient in various consumer products, and it can be a contaminant.

Ethylene Glycol Dihydroxy Dimethyl Ether has also been misused to sweeten wine and beer, and to viscosify oral and topical pharmaceutical products.
Its use has resulted in many epidemics of poisoning since the early 20th century.[3]



PREPARATION OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER:
Ethylene Glycol Dihydroxy Dimethyl Ether is produced by the partial hydrolysis of ethylene oxide.
Depending on the conditions, varying amounts of DEG and related glycols are produced.
The resulting product is two ethylene glycol molecules joined by an ether bond.[5]


"Diethylene glycol is derived as a co-product with ethylene glycol (MEG) and triethylene glycol.
The industry generally operates to maximize MEG production.
Ethylene Glycol Dihydroxy Dimethyl Ether is by far the largest volume of the glycol products in a variety of applications.

Availability of Ethylene Glycol Dihydroxy Dimethyl Ether will depend on demand for derivatives of the primary product, ethylene glycol, rather than on Ethylene Glycol Dihydroxy Dimethyl Ether market requirements."[6]

Structure of Ethylene Glycol Dihydroxy Dimethyl Ether and related polyols[edit]
Diethylene glycol is one of several glycols derived from ethylene oxide.

Glycols related to and co-produced with diethylene glycol and having the formula HOCH2CH2(OCH2CH2)nOH are:
n = 0 ethylene glycol ("antifreeze"); monoethylene glycol MEG
n = 1 DEG
n = 2 triethylene glycol, TEG, or triglycol
n = 3 tetraethylene glycol
n = 4 pentaethylene glycol
n > 4 polyethylene glycol
These compounds are all hydrophilic, more so than most diols, by virtue of the ether functionality.


USES OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER:
Ethylene Glycol Dihydroxy Dimethyl Ether is used in the manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers.[6]
Ethylene Glycol Dihydroxy Dimethyl Ether is used as a building block in organic synthesis of, for example, morpholine and 1,4-dioxane.
Ethylene Glycol Dihydroxy Dimethyl Ether is a solvent for nitrocellulose, resins, dyes, oils, and other organic compounds.

Ethylene Glycol Dihydroxy Dimethyl Ether is a humectant for tobacco, cork, printing ink, and glue.[7]
Ethylene Glycol Dihydroxy Dimethyl Ether is also a component of brake fluid, lubricants, wallpaper strippers, artificial fog and haze solutions, and heating/cooking fuel.[3]

In personal care products (e.g. skin cream and lotions and deodorants), Ethylene Glycol Dihydroxy Dimethyl Ether is often replaced by selected diethylene glycol ethers.
A dilute solution of diethylene glycol can also be used as a cryoprotectant; however, ethylene glycol is much more commonly used.
Most types of ethylene glycol antifreeze contain a few percent of diethylene glycol, present as a by-product of ethylene glycol production.





CHEMICAL AND PHYSICAL PROPERTIES OF ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER:
vapor density
4.6 (vs air)
Quality Level
100
vapor pressure
3 mmHg ( 20 °C)
product line
ReagentPlus®
Assay
99%
form
liquid
autoignition temp.
370 °F
expl. lim.
17.4 %
color
APHA: ≤10
refractive index
n20/D 1.408 (lit.)
pH
7 (20 °C)
bp
162 °C (lit.)
mp
−64 °C (lit.)
density
0.944 g/mL at 20 °C (lit.)
0.939 g/mL at 25 °C (lit.)

SMILES string
COCCOCCOC
InChI
1S/C6H14O3/c1-7-3-5-9-6-4-8-2/h3-6H2,1-2H3
InChI key
SBZXBUIDTXKZTM-UHFFFAOYSA-N
Chemical formula C4H10O3
Molar mass 106.12 g/mol
Appearance Colorless liquid
Density 1.118 g/mL
Melting point −10.45 °C (13.19 °F; 262.70 K)
Boiling point 244 to 245 °C (471 to 473 °F; 517 to 518 K)
Solubility in water miscible

Molecular Weight
106.12 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
XLogP3-AA
-1.3
Computed by XLogP3 3.0 (PubChem release 2021.10.14)
Hydrogen Bond Donor Count
2
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Hydrogen Bond Acceptor Count
3
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Rotatable Bond Count
4
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Exact Mass
106.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Monoisotopic Mass
106.062994177 g/mol
Computed by PubChem 2.2 (PubChem release 2021.10.14)
Topological Polar Surface Area
49.7Ų
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Heavy Atom Count
7
Computed by PubChem
Formal Charge
0
Computed by PubChem
Complexity
26.1
Computed by Cactvs 3.4.8.18 (PubChem release 2021.10.14)
Isotope Atom Count
0
Computed by PubChem
Defined Atom Stereocenter Count
0
Computed by PubChem
Undefined Atom Stereocenter Count
0
Computed by PubChem
Defined Bond Stereocenter Count
0
Computed by PubChem
Undefined Bond Stereocenter Count
0
Computed by PubChem
Covalently-Bonded Unit Count
1
Computed by PubChem
Compound Is Canonicalized
Yes
Water <0.08%
Purity >99.5%
Acidity <0.015%
Appearance Clear colourless liquid
Peroxide <0.005%

Density 0.867 g/cm3 (20 °C)
Flash point 5°C
Ignition temperature 200 °C
Fusion point -58°C
pH value 7 (H₂O) neutral
Vapor pressure 66 hPa (20 °C)
Kinematic viscosity 0.455 mm2/s (25 °C)
Solubility 1000 g/l soluble





SAFETY INFORMATION ABOUT ETHYLENE GLYCOL DIHYDROXY DIMETHYL ETHER
First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.

cas no: 141-97-9 Acetoacetic ester; EAA; Ethyl beta-ketobutyrate; Acetoacetic ester, diacetic ether; Ethyl 3-oxobutanoate; Ethyl acetoacetate; Ethyl acetylacetate; 3-Oxobutanoic acid ethyl ester; Ethyl 3-ketobutyrate; Ethyl acetylacetate; Ethyl acetonecarboxylate; Ethylacetoacetat (German); Acetoacetato de metilo (Spanish); Acétoacétate de méthyle (French);

SYNONYMS Bromoethane; 1-Bromoethane; hydrobromic ether;Bromure D'ethyle; Ethane, Bromo-; Etylu Bromek (Polish); Monobromoethane; Cas no :74-96-4

Glycol Distearate; Ethylene Glycol Dioctadecanoate; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Dioctadecanoate; 1,2-Ethanediyl Octadecanoate CAS NO: 627-83-8

Ethylene glycol monobutyl ether, also known as 2-Butoxyethanol, is an organic compound with an ether-like odor which comes from the family of glycol ethers.
Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether belongs to the class of organic compounds known as dialkyl ethers.


CAS Number: 111-76-2
EC Number: 203-905-0
Chemical formula: C6H14O2


Ethylene glycol monobutyl ether appears as a colorless liquid with a mild, pleasant odor.
Ethylene glycol monobutyl ether is less dense than water.
The flash point of Ethylene glycol monobutyl ether is 160 °F.


Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether has a role as a protic solvent.
Ethylene glycol monobutyl ether is a primary alcohol and a glycol ether.


Ethylene glycol monobutyl ether is a natural product found in Solanum tuberosum, Bidens pilosa, and other organisms with data available.
Ethylene glycol monobutyl ether is a colorless liquid with a mild odor that is used as a solvent in resins, varnishes and lacquers.
Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.


Ethylene glycol monobutyl ether belongs to the class of organic compounds known as dialkyl ethers.
These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are alkyl groups.
Ethylene glycol monobutyl ether is versatile solvent of product obtains by reaction betweeen ethylene oxide and n-Butanol.


Ethylene glycol monobutyl ether is chemically known as a Butyl Glycol, 1-n-Butoxy-2-hydroxyethane, n-butyl (2-hydroxyethyl) ether.
Commercially Ethylene glycol monobutyl ether is known as a Butyl Cellosolve.
Ethylene glycol monobutyl ether is soluble in water, acetone, benzene, ethyl ether, methanol, carbon tetrachloride and other organic solvents and mineral oil.


Ethylene glycol monobutyl ether, also known as 2-Butoxyethanol or butyl cellosolve, is an organic compound with an ether-like odor which comes from the family of glycol ethers.
Ethylene glycol monobutyl ether, also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour.


Ethylene glycol monobutyl ether is a colorless and transparent liquid.
Ethylene glycol monobutyl ether (also called EGMBE and 2-Butoxyethanol) is a colourless, clear liquid with a sweet odour.
Ethylene glycol monobutyl ether is a mutual solvent, and is soluble in both oil and water.


Ethylene glycol monobutyl ether (also known as BG, 2-butoxyethanol, glycol monobutyl ether and butyl cellosolve, butoxyethanol) is a clear, colourless, oily liquid with a unique sweet yet mild odour and has the formula C6H14O2.
Ethylene glycol monobutyl ether is a butyl ether of ethylene glycol and is miscible with water and common organic solvents.


Since Ethylene glycol monobutyl ether dries lacquer coatings very slowly, it is ideal for the preparation of brushing lacquers based on cellulose esters, cellulose ethers and chlorinated rubber.
Even quite small additions of Ethylene glycol monobutyl ether to alkyd, the viscosity of the lacquer solution considerably reduce, thereby improving the brush-out property of such lacquers.


2-Butoxy Ethanol is a good intermediate solvent for use in mineral oil emulsion.
Even small quantities of Ethylene glycol monobutyl ether can disperse and stabilize such emulsion quite effectively.
Ethylene glycol monobutyl ether is versatile solvent of product obtains by reaction betweeen ethylene oxide and n-Butanol.


Ethylene glycol monobutyl ether is chemically known as a Butyl Glycol, 1-n-Butoxy-2-hydroxyethane, n-butyl (2-hydroxyethyl) ether.
Ethylene glycol monobutyl ether, also known as 2-Butoxyethanol or butyl cellosolve, is an organic compound with an ether-like odor which comes from the family of glycol ethers.


In 2006, the European production of butyl glycol ethers amounted to 181 kilotons, of which approximately 50% (90 kt/a) was Ethylene glycol monobutyl ether.
World production is estimated to be 200 to 500 kt/a, of which 75% is for paints and coatings and 18% for metal cleaners and household cleaners.
In the US, Ethylene glycol monobutyl ether is considered a high production volume chemical because more than 100 million pounds of this chemical are produced per year.


Ethylene glycol monobutyl ether is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2).
This colorless liquid, Ethylene glycol monobutyl ether, has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.



USES and APPLICATIONS of ETHYLENE GLYCOL MONOBUTYL ETHER:
Ethylene glycol monobutyl ether is used Aerosol coatings, Aerospace coatings, Architectural coatings, Auto OEM, Auto refinish, Coil coatings, Commerical printing inks, Construction chemicals, Fabric care, Formulators, Furniture, Graphic arts, and Hard surface care.
Ethylene glycol monobutyl ether is used Industrial cleaners, Institutional cleaners, Janitorial & household cleaners, Lubricants, Marine, Oil or gas processing, Paints & coatings, Process solvents, Protective coatings, Rubber modification, Soap/detergents, and Wood coatings.


Ethylene glycol monobutyl ether is also used as an ingredient in paint thinners, herbicides, household products and cosmetics.
A high-boiling (171degreeC) colourless liquid, Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.


Ethylene glycol monobutyl ether is mainly used as a high boiling point solvent for paints, especially nitro spray paints, fast drying paints, varnishes, enamels and paint strippers.
Ethylene glycol monobutyl ether is also used as an inactive diluent for adhesives.


Ethylene glycol monobutyl ether is used Metal detergent, Paint stripper, Fiber wetting agent, Pesticide dispersants, Drug extractants, and Resin plasticizers.
Ethylene glycol monobutyl ether is a colorless liquid with a mild odor that is used as a solvent in resins, varnishes and lacquers.


Other applications of Ethylene glycol monobutyl ether include use as a solvent in printing inks due to its high boiling point, textile dyes and as a component of hydraulic fluids.
Ethylene glycol monobutyl ether is also a component of drilling and cutting oils and is a major component of Corexit 9527, which is an oil spill dispersant product.


Ethylene glycol monobutyl ether is also a chemical intermediate and, as such, is a starting material in the production of butyl glycol acetate which is, itself, an excellent solvent.
Ethylene glycol monobutyl ether is also a starting material in the production of plasticisers by the reaction of phthalic anhydride.


Ethylene glycol monobutyl ether sees use in various industries due to solvent and surfactant properties.
Ethylene glycol monobutyl ether sees extensive use in oil and gas and energy industries as well as household and industrial cleaning products, as well as surface coatings.


Ethylene glycol monobutyl ether has been produced industrially for over half a century and is used primarily as a solvent in paints and surface coatings but also in inks and cleaning products.
Ethylene glycol monobutyl ether has many uses, primarily as a solvent, in both the commercial and industrial industries.


Many other products contain Ethylene glycol monobutyl ether including spray lacquers, varnishes, varnish removers, paints, liquid soaps, degreasers, leather protectors, whiteboard cleaners, printing pastes, enamels, cosmetics and herbicides.
Ethylene glycol monobutyl ether acts as a plasticizer and solvent.


Ethylene glycol monobutyl ether enhances the deformability of polymeric compounds.
Ethylene glycol monobutyl ether is compatible with nitrocellulose and synthetic resins.
Ethylene glycol monobutyl ether is used in plastics.


Ethylene glycol monobutyl ether can be used as a solvent in paint and as a solvent in enamel paint remover.
Ethylene glycol monobutyl ether is a solvent that can also be found in kitchen and all-purpose cleaners.
Ethylene glycol monobutyl ether is used to dissolve oils and grease.


Ethylene glycol monobutyl ether is used as a solvent and to make paints and varnish.
A high-boiling (171℃) colourless liquid, Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.


Ethylene glycol monobutyl ether offers numerous benefits in coating, ink, and cleaner applications.
Ethylene glycol monobutyl ether is an excellent solvent for many coatings resin types, including alkyd, phenolic, maleic, epoxy, and nitrocellulose resins.
Ethylene glycol monobutyl ether is an exceptional retarder solvent for lacquers, improving gloss and flow-out.


Ethylene glycol monobutyl ether is also widely used in amine-solubilized, water-based coatings because of its high flash point, complete water solubility, slow evaporation rate, low surface tension, and high coupling efficiency.
Ethylene glycol monobutyl ether is an effective coalescent that improves film integrity in both architectural and industrial maintenance latex paints.


Ethylene glycol monobutyl ether's unique combination of properties enables the effective removal of contaminants when used in Industrial & Institutional and/or household cleaners.
Ethylene glycol monobutyl ether is used component of cleaning products, cosmetics, lacquers, latex paint, firefighting foam, hydraulic fluid.


Ethylene glycol monobutyl ether is employed primarily in the production of lacquers based on nitrocellulose, cellulose ethers and chlorinated rubber.
Small quantities of Ethylene glycol monobutyl ether are also used combination lacquers.
Solutions of nitrocellulose in Ethylene glycol monobutyl ether may be diluted with large quantity of white spirit, aromatic hydrocarbons or ethanol without adversely affecting the film property.


Small quantities of Ethylene glycol monobutyl ether improves both the flow and dilution capacity of the lacquers and also enhance the gloss of the resultant lacquer films.
As a relatively nonvolatile, inexpensive solvent, Ethylene glycol monobutyl ether is used in many domestic and industrial products because of its properties as a surfactant.
Ethylene glycol monobutyl ether is a glycol ether with modest surfactant properties, which can also be used as a mutual solvent.


-Industry Uses:
Ethylene glycol monobutyl ether usage is dominated by the paint industry which consumes approximately 75 % of all the BG produced.
This is because Ethylene glycol monobutyl ether is a low volatility solvent and can therefore both extend the drying times of coatings and improve their flow.


-Commercial Uses:
Ethylene glycol monobutyl ether is used regularly in most households as it is a component of many home cleaning products.
Ethylene glycol monobutyl ether provides excellent cleaning power for domestic cleaning products and also provides the characteristic odour that we associate with them.
Ethylene glycol monobutyl ether also plays the same role in some industrial and commercial surface cleaners.


-Commercial uses:
Ethylene glycol monobutyl ether is a solvent for paints and surface coatings, as well as cleaning products and inks.
Products that contain Ethylene glycol monobutyl etherinclude acrylic resin formulations, asphalt release agents, firefighting foam, leather protectors, oil spill dispersants, degreaser applications, photographic strip solutions, whiteboard and glass cleaners, liquid soaps, cosmetics, dry cleaning solutions, lacquers, varnishes, herbicides, latex paints, enamels, printing paste, and varnish removers, and silicone caulk.

Products containing Ethylene glycol monobutyl ether are commonly found at construction sites, automobile repair shops, print shops, and facilities that produce sterilizing and cleaning products.
Ethylene glycol monobutyl ether is the main ingredient of many home, commercial and industrial cleaning solutions.

Since the molecule has both polar and non-polar ends, Ethylene glycol monobutyl ether is useful for removing both polar and non-polar substances, like grease and oils.
Ethylene glycol monobutyl ether is also approved by the U.S. FDA to be used as direct and indirect food additives, which include antimicrobial agents, defoamers, stabilizers, and adhesives.


-In the petroleum industry:
Ethylene glycol monobutyl ether is commonly produced for the oil industry because of its surfactant properties.
In the petroleum industry, Ethylene glycol monobutyl ether is a component of fracturing fluids, drilling stabilizers, and oil slick dispersants for both water-based and oil-based hydraulic fracturing.

When liquid is pumped into the well, the fracturing fluids are pumped under extreme pressure, so Ethylene glycol monobutyl ether is used to stabilize them by lowering the surface tension.
As a surfactant, Ethylene glycol monobutyl ether absorbs at the oil-water interface of the fracture.
Ethylene glycol monobutyl ether is also used to facilitate the release of the gas by preventing congealing.

Ethylene glycol monobutyl ether is also used as a crude oil–water coupling solvent for more general oil well workovers.
Because of its surfactant properties, Ethylene glycol monobutyl ether is a major constituent (30–60% w/w) in the oil spill dispersant Corexit 9527, which was widely used in the aftermath of the 2010 Deepwater Horizon oil spill.



HOW IS ETHYLENE GLYCOL MONOBUTYL ETHER PRODUCED?
Ethylene glycol monobutyl ether is produced by reacting ethylene oxide with an alcohol such as normal butanol (nbutanol) within a catalyst.
This process is called ethoxylation.
If the ratio of ethylene oxide to nbutanol is greater than one then di- and tri- ethylene glycol monoethers are also produced.
Below is the chemical equation for this reaction:
C2H4O + C4H9OH → C4H9OC2H4OH
World production is estimated at between 300-500 KT per annum. Ethylene glycol monobutyl ether can also be produced through the etherification of butanol with 2-chloroethanol.



WHERE IS ETHYLENE GLYCOL MONOBUTYL ETHER FOUND AND HOW IS ETHYLENE GLYCOL MONOBUTYL ETHER USED?
Ethylene glycol monobutyl ether itself is not commercially produced in Canada.
Ethylene glycol monobutyl ether is widely used in a range of commercial and consumer products, such as paints, cleaning products and solvents, as well as in some industrial applications.



PRODUCTION OF ETHYLENE GLYCOL MONOBUTYL ETHER:
Ethylene glycol monobutyl ether is commonly obtained through two processes; the ethoxylation reaction of butanol and ethylene oxide in the presence of a catalyst:

C2H4O + C4H9OH → C4H9OC2H4OH
or the etherification of butanol with 2-chloroethanol.
Ethylene glycol monobutyl ether can be obtained in the laboratory by performing a ring opening of 2-propyl-1,3-dioxolane with boron trichloride.
Ethylene glycol monobutyl ether is often produced industrially by combining ethylene glycol and butyraldehyde in a Parr reactor with palladium on carbon.



KEY ATTRIBUTES OF ETHYLENE GLYCOL MONOBUTYL ETHER:
*Efficient coalescent
*Excellent coupling efficiency
*Good solvent activity
*High blush resistance
*Inert - Food use with limitations
*Inert - Nonfood use
*Low surface tension
*Miscible with water and most organic liquids
*Non-HAP
*REACH compliant
*Readily biodegradable
*Slow evaporation rate



ALTERNATIVE PARENTS OF ETHYLENE GLYCOL MONOBUTYL ETHER:
*Primary alcohols
*Hydrocarbon derivatives



SUBSTITUENTS OF ETHYLENE GLYCOL MONOBUTYL ETHER:
*Dialkyl ether
*Hydrocarbon derivative
*Primary alcohol
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE GLYCOL MONOBUTYL ETHER:
Chemical formula: C6H14O2
Molar mass: 118.176 g·mol−1
Appearance: Clear, colorless liquid
Density: 0.90 g/cm3, liquid
Melting point: −77 °C (−107 °F; 196 K)
Boiling point: 171 °C (340 °F; 444 K)
Solubility in water: Miscible (and in most organic solvents)
Vapor pressure: 0.8 mmHg
Acidity (pKa): High pKa for −OH group
Refractive index (nD): 1.4198 (20 °C)
Viscosity: 2.9 cP at 25 °C (77 °F)
Dipole moment: 2.08 D
Flash point: 67 °C (153 °F; 340 K)
Autoignition temperature: 245 °C (473 °F; 518 K)
Explosive limits: 1.1–12.7%

Molecular Weight: 118.17 g/mol
XLogP3: 0.8
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 118.099379685 g/mol
Monoisotopic Mass: 118.099379685 g/mol
Topological Polar Surface Area: 29.5Ų
Heavy Atom Count: 8
Formal Charge: 0
Complexity: 37.5
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
CAS number: 111-76-2
EC index number: 603-014-00-0
EC number: 203-905-0
Hill Formula: C₆H₁₄O₂
Chemical formula: C₄H₉OCH₂CH₂OH
Molar Mass: 118.18 g/mol
HS Code: 2909 43 00
Density: 0.90 g/cm3 (20 °C)
Explosion limit: 1.1 - 10.6 %(V)
Flash point: 67 °C
Melting Point: -75 °C
pH value: 7 (H₂O, 20 °C) (as aqueous solution)
Vapor pressure: 0.8 hPa (20 °C)
Viscosity kinematic: 3.642 mm2/s (20 °C)
Solubility: 900 g/l soluble
Density: 0.90 g/cm3 (20 °C)
Explosion limit: 1.1 - 10.6 %(V)

Flash point: 67 °C
Melting Point: -75 °C
pH value: 7 (H₂O, 20 °C) (as aqueous solution)
Vapor pressure: 0.8 hPa (20 °C)
Viscosity kinematic: 3.642 mm2/s (20 °C)
Solubility: 900 g/l soluble
Physical state: liquid
Color: colorless
Odor: ether-like, mild, sweet
Melting point/freezing point:
Melting point/range: -75 °C
Initial boiling point and boiling range: 173,5 °C at 1.013 hPa - (ECHA)
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 12,7 %(V)
Lower explosion limit: 1,1 %(V)
Flash point: 67 °C
Autoignition temperature: 230 °C
at 1.013,25 hPa - DIN 51794

Decomposition temperature: Distillable in an undecomposed state at normal pressure.
pH 7 at 20 °C (as aqueous solution)
Viscosity
Viscosity, kinematic: 3,642 mm2/s at 20 °C2,284 mm2/s at 40 °C
Viscosity, dynamic: 3,6 mPa.s at 20 °C
Water solubility: No data available
Partition coefficient: n-octanol/water: log Pow: 0,81 at 25 °C
Vapor pressure: No data available
Density: 0,90 g/cm3 at 20 °C - DIN 51757
Relative density: No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none
Other safety information:
Surface tension: 65,03 mN/m at 2g/l at 20 °C
Relative vapor density: 4,08 - (Air = 1.0)

Formula: C6H14O2
Formula mass: 118.18
Melting point, °C: -70
Boiling point, °C: 171
Vapor pressure, mmHg: 0.8 (20 C)
Vapor density (air=1): 4.1
Saturation Concentration: 0.1% at 20 C
Evaporization number: 0.07 (butyl acetate = 1)
Critical temperature: 370
Critical pressure: 38.50
Density: 0.902 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.87 cp (40 C)
Surface tension: 27.4 g/s2 @ 25 C.
Refractive index: 1.4196 (20 C)
Dipole moment: 1.8 D
Dielectric constant: 9.4 (20 C)
Partition coefficient, pKow: 0.83

Heat of vaporization: 47.1 kJ/mol
Heat of combustion: -4163 kJ/mol
Boiling Range: 2°C max.
Melting Point: -70°C
Color: Yellow
Density: 0.901g/cm³
Boiling Point: 171°C
Linear Formula: HOCH2CH2O(CH2)3CH3
UN Number: 2810
Refractive Index: 1.418 to 1.420 (at 20°C)
Formula Weight: 118.18
Vapor Pressure: 0.8 hPa at 20°C
Physical Form: Liquid
Chemical Name or Material: Ethylene Glycol Monobutyl Ether

Cas Number: 111-76-2
Molecular Mass: 118.176 g/mol1
Exact Mass: 118.09938 g/mol
Flashpoint: 153 °F / 67 °C
Boiling Point: 340 °F / 171 °C
Melting Point: -107 °F / -77 °C
Vapour Pressure: 0.76 mm Hg at 68 ° F
Water Solubility: ≥ 100 mg/ml (72° F)
Density: 0.90 g/cm3
Log P: 0.83
Chemical Formula: C6H14O2
Average Molecular Mass: 118.174 g/mol
Monoisotopic Mass: 118.099 g/mol
CAS Registry Number: 111-76-2
IUPAC Name: 2-butoxyethan-1-ol
Traditional Name: butoxyethanol
SMILES: CCCCOCCO
InChI Identifier: InChI=1S/C6H14O2/c1-2-3-5-8-6-4-7/h7H,2-6H2,1H3
InChI Key: POAOYUHQDCAZBD-UHFFFAOYSA-N

Water Solubility: 76.5 g/L
logP: 0.78
logP: 0.76
logS: -0.19
pKa (Strongest Acidic): 15.12
pKa (Strongest Basic): -2.7
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 29.46 Ų
Rotatable Bond Count: 5
Refractivity: 33.18 m³·mol⁻¹
Polarizability: 14.37 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: No
Veber's Rule: Yes
MDDR-like Rule: No



FIRST AID MEASURES of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Consult a physician.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Call a physician immediately.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,4 mm
Break through time: 120 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter A (acc. to DIN 3181)
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Precautions for safe handling
*Advice on safe handling
Work under hood.
*Advice on protection against fire and explosion
Take precautionary measures against static discharge.
*Hygiene measures
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities
*Storage conditions
Do not use light-weight-metal containers.
Protected from light.
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Recommended storage temperature see product label.



STABILITY and REACTIVITY of ETHYLENE GLYCOL MONOBUTYL ETHER:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Incompatible materials:
No data available



SYNONYMS:
2-Butoxyethanol
111-76-2
ETHYLENE GLYCOL MONOBUTYL ETHER
Butyl glycol
Butyl cellosolve
Butoxyethanol
n-Butoxyethanol
Ethanol, 2-butoxy-
Ethylene glycol butyl ether
Butyl oxitol
Dowanol EB
Glycol butyl ether
Glycol ether eb
3-Oxa-1-heptanol
2-butoxyethan-1-ol
EGBE
2-Butoxy-1-ethanol
Gafcol EB
2-n-Butoxyethanol
O-Butyl ethylene glycol
Jeffersol eb
Butyl cellu-sol
BUCS
Ektasolve EB
Glycol monobutyl ether
Chimec NR
2-Butoxy ethanol
2-Butossi-etanolo
2-Butoxy-aethanol
Butylcelosolv
Butylglycol
Butoksyetylowy alkohol
2-Butoxy-ethanol
Ethylene glycol n-butyl ether
EGMBE
Monobutyl glycol ether
Monobutyl ether of ethylene glycol
Ethylene glycol mono-n-butyl ether
n-Butyl Cellosolve
.beta.-Butoxyethanol
9004-77-7
Butyl monoether glycol
Caswell No. 121
Butyglycol
Monobutyl ethylene glycol ether
2-n-Butoxy-1-ethanol
Ether alcohol
Ethylene glycol, monobutyl ether
Butyl icinol
g lycol ether eb
beta-Butoxyethanol
2 -Butoxyethanol
Minex BDH
2-Hydroxyethyl n-butyl ether
Butoxyethanol, 2-
ethyleneglycol monobutyl ether
Ektasolve EB solvent
CCRIS 5985
HSDB 538
2-Butoxyethanol (ethylene glycol monobutyl ether)
2-Butoxyethan(ol-d)
2-Butoxyethanol--d4
Ek tasolve EB solvent
Eter monobutilico del etilenglicol
Glycol ether eb acetate
EINECS 203-905-0
UNII-I0P9XEZ9WV
UN2369
I0P9XEZ9WV
Butyl 2-hydroxyethyl ether
EPA Pesticide Chemical Code 011501
BRN 1732511
AI3-0993
AI3-09903
NSC-60759
2-BUTOXY(ETHANOL-13C2)
EC 203-905-0
EC 500-012-0
Ethylene glycol monobutyl ether (EGBE)(2-Butoxyet)
DTXCID904097
2-BUTOXY ETHANOL (ETHYLENE GLYCOL MONOBUTYL ETHER)
butylcellosolve
CAS-111-76-2
SMR001253761
n-butoxyethanol sodium salt
Butyloxitol
2-Butoksyetanol
2-Butoxietanol
EB Solvent
2- butoxyethanol
3-oxaheptan-1-ol
Etanol, 2-butoxi-
2-(n-Butoxy)ethanol
BuOCH2CH2OH
EGM (CHRIS Code)
Ethylene glycol monobutyl
2-Butoxyethanol (EGBE)
2-(1-Butyloxy) ethanol
Aethylenglycolmonobuthylaether
BUTOXYETHANOL [INCI]
2-Butoxy-aethanol(GERMAN)
SCHEMBL15712
Ethyleneglycol-monobutyl ether
MLS002174253
MLS002454362
WLN: Q2O4
BUTYL CELLOSOLVE [MI]
ethylene glycol-monobutyl ether
CHEMBL284588
QSPL 003
2-BUTOXYETHANOL [IARC]
2-BUTOXYETHANOL [VANDF]
Ethylene glycol butyl ether, 99%
2-butoxyethanol (butyl cellosolve)
NSC60759
(C2-H4-O)mult-C4-H10-O
ther d'thylneglycol et de monobutyle
Tox21_202399
Tox21_300123
LS-539
MFCD00002884
NA2369
Ethylene glycol butyl ether, >=99%
AKOS009028760
Ethylene glycol monobutyl ether (EGBE)
NCGC00090683-01
NCGC00090683-02
NCGC00090683-03
NCGC00090683-04
NCGC00090683-05
NCGC00254083-01
NCGC00259948-01
Ethylene glycol monobutyl ether (EGBE)
B0698
FT-0626297
UVCB substance. IUPAC name not applicable.
EN300-19317
C19355
500-012-0 (NLP #)
Ethylene glycol butyl ether, analytical standard
ETHYLENE GLYCOL MONO-N-BUTYL ETHER [HSDB]
Q421557
Ethylene glycol butyl ether, for synthesis, 99.0%
J-508565
Butoxyethanol, 2-
(Glycol ether EB; Xtraction II)
Butoxyethanol, 2-
(Glycol ether EB; Xtraction II)
Ethylene glycol butyl ether, SAJ first grade, >=99.0%
Ethylene glycol monobutyl ether (EGBE) (2-Butoxyethanol)
Ethylene glycol butyl ether, spectrophotometric grade, >=99.0%
Ethylene glycol monobutyl ether [UN2369]
Ethylene glycol monobutyl ether [UN2369]
EGBE, AI-0993
Bucs
Butoxyethanol
Beta-butoxyethanol
2-Butoxyethanol
2-butoxy-1-ethanol
Butyl cellosolve
o-butyl ethylene glycol
Butyl glycol
Butyl oxitol
Caswell No. 121
Ethylne glycol butyl ether
Ethylene glycol monobutyl ether
Glycol butyl ether
Monobutyl glycol ether
3-oxa-1-heptanol
EPA Pesticide Code: 011501
2-Butoxyethanol
Butyl Cellosolve
Butyl Monoether Glycol
Ethylene Glycol Monobutyl Ether (EGBE)
Butoxyethanol
2-Butoxyethanol
Butyl Cellosolve
n-Butyl Glycol
Butyl Glycol
2‐n‐Butoxyethanol
2-Butoxyethyl acetate
Butyl Cellosolve acetate
Butyl glycol acetate
EGBEA
Ektasolve EB acetate
Ethylene glycol monobutyl ether acetate
2-Hydroxyethyl N-butyl ether
3-Oxa-1-heptanol
BuOCH2ch2oh
Butoxyethanol
Butyl cellosolve
Butyl glycol
Butyl oxitol
Ethylene glycol butyl ether
Ethylene glycol mono-N-butyl ether
Ethylene glycol monobutyl ether
Glycol butyl ether
N-Butoxyethanol ChEBI
O-Butyl ethylene glycol
2-Butossi-etanolo
2-Butoxy ethanol
2-BUTOXY ethanol (ethylene glycol monobutyl ether)
2-Butoxy-1-ethanol
2-Butoxy-aethanol
2-Butoxy-ethanol
2-Butoxyethan-1-ol
2-Butoxyethanol (butyl cellosolve)
2-Butoxyethanol (ethylene glycol monobutyl ether)
2-N-Butoxy-1-ethanol
2-N-Butoxyethanol
beta-Butoxyethanol
BUCS
Butoksyetylowy alkohol
Butyglycol
Butyl 2-hydroxyethyl ether
Butyl cellu-sol
Butyl icinol
Butyl monoether glycol
Butylcellosolve
Butylcelosolv
Butylglycol
Butyloxitol
Chimec NR
Dowanol eb
Eb solvent
EGBE
Egmbe
Eter monobutilico del etilenglicol
Ether alcohol
Ethylene glycol mono butyl ether
Ethylene glycol monobutyl ether (egbe)(2-butoxyet)
Ethylene glycol N-butyl ether
Ethylene glycol, monobutyl ether
Ethyleneglycol monobutyl ether
Gafcol eb
Glycol monobutyl ether
Minex BDH
Monobutyl ether OF ethylene glycol
Monobutyl ethylene glycol ether
Monobutyl glycol ether
N-Butoxyethanol sodium salt
N-Butyl cellosolve
Poly-solv eb
2-Butoxyethanol,2-(1-butoxy)ethanol,2-be
2-Butossi-etanolo
2-Butoxy-1-ethanol·2-Butoxy-aethanol
2-Butoxyethan-1-ol
2-butoxy-ethano
2-butoxyethanol (butyl cellosolve)

DESCRIPTION:

Ethylene glycol monobutyl ether is a primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group.
Ethylene glycol monobutyl ether has a high-boiling (171℃) colourless liquid.
Ethylene glycol monobutyl ether is used as a solvent for paints and inks, as well as in some dry cleaning solutions.



CAS NUMBER: 111-76-2

MOLECULAR FORMULA: CH3(CH2)2CH2OCH2CH2OH

MOLECULAR WEIGHT: 118.17




DESCRIPTION:

Ethylene glycol monobutyl ether has a role as a protic solvent.
Ethylene glycol monobutyl ether is a primary alcohol and a glycol ether.
Ethylene glycol monobutyl ether is a natural product.
Ethylene glycol monobutyl ether appears as a colorless liquid with a mild, pleasant odor.

Ethylene glycol monobutyl ether is a colorless liquid with a mild, pleasant odor.
Ethylene glycol monobutyl ether has less dense than water.
Ethylene glycol monobutyl ether's flash point is 160°F.
Ethylene glycol monobutyl ether irritates skin and eyes.

Ethylene glycol monobutyl ether is used as a solvent and to make paints and varnish.
Ethylene glycol monobutyl ether is an organic compound with the chemical formula BuOC2H4OH (Bu = CH3CH2CH2CH2).
This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.
As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant.

Ethylene glycol monobutyl ether can be obtained in the laboratory by performing a ring opening of 2-propyl-1,3-dioxolane with boron trichloride.
Ethylene glycol monobutyl ether offers numerous benefits in coating, ink, and cleaner applications.
Ethylene glycol monobutyl ether is an excellent solvent for many coatings resin types, including alkyd, phenolic, maleic, epoxy, and nitrocellulose resins.
Ethylene glycol monobutyl ether is an exceptional retarder solvent for lacquers, improving gloss and flow-out.

Ethylene glycol monobutyl ether is also widely used in amine-solubilized, water-based coatings because of its high flash point, complete water solubility, slow evaporation rate, low surface tension, and high coupling efficiency.
Ethylene glycol monobutyl ether is an effective coalescent that improves film integrity in both architectural and industrial maintenance latex paints.
Ethylene glycol monobutyl ether's unique combination of properties enables the effective removal of contaminants when used in Industrial & Institutional and/or household cleaners.

Ethylene glycol monobutyl ether is a clear, colourless, oily liquid with a unique sweet yet mild odour and has the formula C6H14O2.
Ethylene glycol monobutyl ether is a butyl ether of ethylene glycol and is miscible with water and common organic solvents.
Ethylene glycol monobutyl ether has been produced industrially for over half a century and is used primarily as a solvent in paints and surface coatings but also in inks and cleaning products.



APPLICATION:

-Aerosol coatings
-Aerospace coatings
-Architectural coatings
-Auto OEM
-Auto refinish
-Coil coatings
-Commerical printing inks
-Construction chemicals
-Fabric care
-Formulators
-Furniture
-Graphic arts
-Hard surface care
-Industrial cleaners
-Institutional cleaners
-Janitorial & household cleaners
-Lubricants
-Marine
-Oil or gas processing
-Paints & coatings
-Process solvents
-Protective coatings
-Rubber modification
-Soap/detergents
-Wood coatings



BENEFITS:

-Efficient coalescent
-Excellent coupling efficiency
-Good solvent activity
-High blush resistance
-Inert - Food use with limitations
-Inert - Nonfood use
-Low surface tension
-Miscible with water and most organic liquids
-Non-HAP
-REACH compliant
-Readily biodegradable
-Slow evaporation rate



PROPERTIES:

-Melting Point: -75 °C
-Boiling Point: 171 °C
-Flash point: 68 °C
-Specific Gravity (20/20): 0.90
-Refractive Index: 1.42
-Solubility in water: Completely miscible
-Solubility (miscible with): Alcohol, Ether, Benzene, Heptane, Acetone



PHYSICAL PROPERTIES:

-Boiling Point °C: 171.2
-Melting Point °C: -70.0
-Specific Gravity 20/20°C: 0.902
-Flash Point (closed cup) °C: 67.5



PHYSICAL AND CHEMICAL PROPERTIES:

-Density: 0.90 g/cm3 (20 °C)
-Explosion limit: 1.1 - 10.6 %(V)
-Flash point: 67 °C
-Melting Point: -75 °C
-pH value: 7 (H₂O, 20 °C) (as aqueous solution)
-Vapor pressure: 0.8 hPa (20 °C)
-Viscosity kinematic: 3.642 mm2/s (20 °C)
-Solubility: 900 g/l soluble



PROPERTIES:

-Molecular Weight: 118.17
-XLogP3: 0.8
-Hydrogen Bond Donor Count: 1
-Hydrogen Bond Acceptor Count: 2
-Rotatable Bond Count: 5
-Exact Mass: 118.099379685
-Monoisotopic Mass: 118.099379685
-Topological Polar Surface Area: 29.5 Ų
-Heavy Atom Count: 8
-Complexity: 37.5
-Isotope Atom Count: 0
-Defined Atom Stereocenter Count: 0
-Undefined Atom Stereocenter Count: 0
-Defined Bond Stereocenter Count: 0
-Undefined Bond Stereocenter Count: 0
-Covalently-Bonded Unit Count: 1
-Compound Is Canonicalized: Yes



SPECIFICATION:

-Assay (GC, area%): ≥ 99.0 % (a/a)
-Density (d 20 °C/ 4 °C): 0.900 - 0.901
-Water (K. F.): ≤ 0.20 %
-Peroxide (as H₂O₂): ≤ 0.05 %
-Identity (IR): passes test



STORAGE:

Store below +30°C.



SYNONYM:

2-Butoxyethanol
111-76-2
ETHYLENE GLYCOL MONOBUTYL ETHER
Butyl glycol
Butyl cellosolve
Butoxyethanol
n-Butoxyethanol
Ethanol, 2-butoxy
Ethylene glycol butyl ether
Butyl oxitol
Dowanol EB
Glycol butyl ether
Glycol ether eb
3-Oxa-1-heptanol
2-butoxyethan-1-ol
EGBE
2-Butoxy-1-ethanol
Gafcol EB
2-n-Butoxyethanol
O-Butyl ethylene glycol
Jeffersol eb
Butyl cellu-sol
BUCS
Ektasolve EB
Glycol monobutyl ether
Chimec NR
2-Butoxy ethanol
2-Butossi-etanolo
2-Butoxy-aethanol
Butylcelosolv
Butylglycol
Butoksyetylowy alkohol
2-Butoxy-ethanol
Ethylene glycol n-butyl ether
EGMBE
Monobutyl glycol etherMonobutyl ether of ethylene glycol
Ethylene glycol mono-n-butyl ethern-Butyl Cellosolve
.beta.-Butoxyethanol
ethyleneglycol monobutyl ether
Butyl monoether glycol
Butyglycol
Monobutyl ethylene glycol ethe
2-n-Butoxy-1-ethanol
Ether alcohol
Ethylene glycol, monobutyl ether
Butyl icinol
Minex BDH
NSC 60759
2-Hydroxyethyl n-butyl ether
2-Butoxyethanol (ethylene glycol monobutyl ether)
9004-77-7
Eter monobutilico del etilenglicol
I0P9XEZ9WV
Butyl 2-hydroxyethyl ether
Ether monobutylique de l'ethyleneglycol
DTXSID1024097
CHEBI:63921
NSC-60759
DTXCID904097
butylcellosolve
g lycol ether eb
beta-Butoxyethanol
2 -Butoxyethanol
CAS-111-76-2
SMR001253761
Butoxyethanol, 2-
Ektasolve EB solvent
CCRIS 5985
HSDB 538
Ek tasolve EB solvent
Glycol ether eb acetate
EINECS 203-905-0
UNII-I0P9XEZ9WV
UN2369
n-butoxyethanol sodium salt
EPA Pesticide Chemical Code 011501
BRN 1732511
Butyloxitol
AI3-0993
butoxy-ethanol
AI3-09903
Ethylene glycol mono butyl ether
Butyl Glycolether
EB Solvent
3-oxaheptan-1-ol
2-(n-Butoxy)ethanol
BuOCH2CH2OH
2-(1-Butyloxy) ethanol
EC 203-905-0
EC 500-012-0
Aethylenglycolmonobuthylaether
BUTOXYETHANOL [INCI]
2-Butoxy-aethanol(GERMAN)
SCHEMBL15712MLS002174253
MLS002454362
WLN: Q2O4
BUTYL CELLOSOLVE
Butyglycol(FRENCH, GERMAN
Ethylene glycol monobutyl ether
ethylene glycol-monobutyl ether
CHEMBL284588
QSPL 003
2-BUTOXYETHANOL
2-BUTOXYETHANOL
2-BUTOXY ETHANOL (ETHYLENE GLYCOL MONOBUTYL ETHER)
Ethylene glycol butyl ether, 99%
2-butoxyethanol
NSC60759
ZINC1690437
Tox21_202399
Tox21_300123
MFCD00002884
Ethylene glycol butyl ether, >=99%
AKOS009028760
NCGC00090683-01
NCGC00090683-02
NCGC00090683-03
NCGC00090683-04
NCGC00090683-05
NCGC00254083-01
NCGC00259948-01
LS-13220
B0698
FT-0626297
EN300-19317
Ethylene Glycol Monobutyl Ether Reagent Grade
C19355
Ethylene glycol butyl ether, analytical standard
ETHYLENE GLYCOL MONO-N-BUTYL ETHER
Q421557
Ethylene glycol butyl ether, for synthesis, 99.0%
J-508565
Ethylene glycol butyl ether, SAJ first grade, >=99.0%
Ethylene glycol butyl ether, spectrophotometric grade, >=99.0%

cas no 111-60-4 Glycol Monostearate ; Octadecanoic Acid, 1,2-Ethanediyl Ester; Ethylene Octadecanoate; 1,2-Ethanediyl Octadecanoate; Ethylene Glycol Monooctadecanoate; 2-Hydroxyethyl stearate;

Ethylene glycol n-hexyl ether is a colorless liquid with a slight ether odor and bitter taste.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.
Ethylene glycol n-hexyl ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.


CAS number: 112-25-4
EC number: 203-951-1
MDL Number: MFCD00045997
Molecular formula: C8H18O2


Ethylene glycol n-hexyl ether is a solvent that can be found in a variety of rust removers, hard surface cleaners and disinfectants.
Ethylene glycol n-hexyl ether, as known 2-Hexoxyethanol or 2-(Hexyloxy)ethanol, is a glycol ether that has a chemical formula of C8H18O2.
Ethylene glycol n-hexyl ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.


Ethylene glycol n-hexyl ether is a colorless liquid with a slight ether-like odor and bitter taste.
Ethylene glycol n-hexyl ether's miscibility with water, however, is limited.
Ethylene glycol n-hexyl ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
As a result, Ethylene glycol n-hexyl ether provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.


Ethylene glycol n-hexyl ether (Ethylene Glycol Monohexyl Ether), n°112-25-4 is measured by GC-FID.
Ethylene glycol n-hexyl ether's vapour is heavier than air.
Since Ethylene glycol n-hexyl ether may react with the oxygen in the air to form peroxides.
Ethylene glycol n-hexyl ether (Cas No.: 112-25-4) is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.


Ethylene glycol n-hexyl ether's miscibility with water, however, is limited.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functionalgroups in the same molecule.
Ethylene glycol n-hexyl ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.


Ethylene glycol n-hexyl ether is a Glycol ether solvent.
n-Hexylglycol enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Since Ethylene glycol n-hexyl ether may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2,6-di-tert-butyl-para cresol (butylated hydroxytoluene – BHT).


Ethylene glycol n-hexyl ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Ethylene glycol n-hexyl ether has the characteristic structure of glycol ethers and contains both ether and alcohol functional groups in the same molecule.


Ethylene glycol n-hexyl ether is a high boiling point, slow evaporating rate solvent with excellent solvency characteristics.
Ethylene glycol n-hexyl ether Solvent is a high boiling point, slow evaporating rate solvent with excellent solvencycharacteristics.
Ethylene glycol n-hexyl ether has a high boiling point, slow evaporating solvent with excellent solvency characteristics.



USES and APPLICATIONS of ETHYLENE GLYCOL N-HEXYL ETHER:
Ethylene glycol n-hexyl ether is used to break down soils and grease stains.
Ethylene glycol n-hexyl ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Ethylene glycol n-hexyl ether is used as a coalescing agent in latex paints and cleaners.
For instance, it improves the flow of many baking finish systems.


Ethylene glycol n-hexyl ether is used Industry, Scientific Research, Health, Environmental Protection, Agriculture.
Ethylene glycol n-hexyl ether plays an important role in speciality printing inks.
Ethylene glycol n-hexyl ether is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Ethylene glycol n-hexyl ether is used Clear, mobile, high-boiling, low-volatility liquid for use as a solvent, flow promoter and coalescent.


Ethylene glycol n-hexyl ether can be used as a solvent for paints, paints, resins, dyes, oils and lubricating oils, as well as coupling and dispersing agents.
By virtue of its good solvent power, the main applications of n-Hexylglycol are as a solvent, flow promoter and coalescent aid.
Ethylene glycol n-hexyl ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.


Other uses of Ethylene glycol n-hexyl ether are: Sealants, Adhesives, Coating products, Finger Paints, Fillers, Anti-freeze products, Plasters, Putties, Lubricants, Modelling Clay, Greases, Automotive care products, Machine wash liquids/detergents, Air fresheners, Fragrances, and Other outdoor use.
Ethylene glycol n-hexyl ether serves as a coalescing agent in cleaners and latex paints.


Ethylene glycol n-hexyl ether can also be used in printing inks and cleaners.
Ethylene glycol n-hexyl ether possesses high boiling point.
Usage of Ethylene glycol n-hexyl ether: Laboratory Reagents, Analytical Reagents, Diagnostic Reagents, Teaching Reagents


Ethylene glycol n-hexyl ether is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry and in printing inks and cleaners.
Two solvents, Ethylene glycol n-hexyl ether and diethylene glycol hexyl ether, are potential replacements for halogenated hydrocarbons in non-vapor degreasing applications.


Ethylene glycol n-hexyl ether has excellent oil solubility, making it effective in household and industrial cleaning applications.
Ethylene glycol n-hexyl ether is used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.
Ethylene glycol n-hexyl ether is used as a coalescing agent in latex paints and cleaners.


Ethylene glycol n-hexyl ether can be used as a solvent in lacquers, paints, resins, dyes, oils and lubricants, as well as as a coupling and dispersant.
Ethylene glycol n-hexyl ether is used as a high-boiling solvent.
Ethylene glycol n-hexyl ether is used as special solvent for coating and ink.


Ethylene glycol n-hexyl ether is used as high-boiling solvent.
Ethylene glycol n-hexyl ether is used as a chemical intermediate for hexyloxyethyl phosphate and neopentanoate.
Ethylene glycol n-hexyl ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.


As a result, Ethylene glycol n-hexyl ether provides unique cleaning power for removal of both water-soluble andgreasy (water insoluble) soils.
Ethylene glycol n-hexyl ether can be used as solvent in specialty printing inks.
Ethylene glycol n-hexyl ether plays an important role in specialty printing inks. Because of its limited water solubility andslow evaporation.
Ethylene glycol n-hexyl ether exhibits very good solvency, superior oil solubility, and slow evaporation rate.


Ethylene glycol n-hexyl ether is used for Biological Purpose, For Microscopic Purpose, For Lens Blooming, Technical Grade, Pratical Use, Pro Analysis, Super Special Grade, For Synthesis, For Electrophoresis Use.
Ethylene glycol n-hexyl ethercan be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.


Ethylene glycol n-hexyl ether can be used as coalescent for water-borne.
The linear hexyl portion of this provides excellent oil solubility characteristics that make Ethylene glycol n-hexyl ether useful in both consumer and industrial cleaner applications.
Added in small proportions to formulations for electrodeposition paints, it greatly improves film formation and levelling.


Ethylene glycol n-hexyl ether is also eminently suitable as a mild, low-odour co-solvent in low-aromatic mineral spirit blends for dissolving polymer binders such as Acronal 260 F.
Ethylene glycol n-hexyl ether is mainly used as solvents for cleaning fluids, paints, coatings and ink preparations.


Ethylene glycol n-hexyl ether is used as high-boiling solvent, Solvents (which become part of product formulation or mixture), and Cleaning and furnishing care products.
Because of its limited water solubility and slow evaporation, Ethylene glycol n-hexyl ether can be used in formulations for the silk screen process to prevent premature setting of the ink.


Ethylene glycol n-hexyl ether is used as a coalescing agent for water-based latex-based coatings and plays an important role in specialty printing inks, including screen printing processes, where its limited water solubility and slow evaporation rate prevent premature ink settling.
Ethylene glycol n-hexyl ether is used as solvents in specialty printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.


The linear hexyl portion of Ethylene glycol n-hexyl ether provides excellent oilsolubility characteristics that make it useful in both consumer and industrial cleaner applications.
Ethylene glycol n-hexyl ether can be used in formulations for the silk screen process to prevent premature setting of the ink.
Ethylene glycol n-hexyl ether can be used as primary solvent in solvent-based silk screen printing inks.


Ethylene glycol n-hexyl ether is used as solvents in specialty printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene glycol n-hexyl ether is used as a high-boiling solvent.


-Applications of Ethylene glycol n-hexyl ether:
• Specialty printing inks
• Coalescent for water-borne, latex-based coatings, coupling agent and solvent in household and industrial cleaners, rust removers, hard surface cleaners, and disinfectants
• Primary solvent in solvent-based silk screen printing inks


-Uses of Ethylene glycol n-hexyl ether:
*Cosmetics
*Cleaners
*Textiles
*Waterborne coatings
*Cleaning
*Printing ink



ALTERNATIVE PARENTS of ETHYLENE GLYCOL N-HEXYL ETHER:
*Primary alcohols
*Hydrocarbon derivatives



SUBSTITUENTS of ETHYLENE GLYCOL N-HEXYL ETHER:
*Dialkyl ether
*Hydrocarbon derivative
*Primary alcohol
*Alcohol
*Aliphatic acyclic compound



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENE GLYCOL N-HEXYL ETHER:
Molar mass 146.23 g/mol
n-Hexylglycol: 98.0 min. %
Water: 0.1 max. %
Pt/Co color value (Hazen): 10 max.
Acid value: 0.1 max mg KOH/g
Boiling range at 1013 hPa; 95 Vol.-%; 2 – 97 ml 200 – 212 °C
Density at 20 °C: 0.887 – 0.890 g/cm3
Refractive index: nD20 1.428 – 1.430
Solidification point: at 1013 hPa - 42 °C (ice flakes)
Evaporation rate ether: 1 approx. 1200
Enthalpy of combustion: at 25 °C 33 136 kJ/kg -
Enthalpy of vaporization: at 25 °C 475 kJ/kg -
Enthalpy of vaporization: at boiling point 325 kJ/kg
Enthalpy of formation: at 25 °C - 3 776 kJ/kg -

Dipole moment: (µ) 2.08 D
Solubility Mass fraction of Hexyl glycol in water: 1.0 %
Water in Hexyl glycol: 18.8 %
Water Solubility: 4.22 g/L
logP: 1.82
logP: 1.65
logS: -1.5
pKa (Strongest Acidic): 15.12
pKa (Strongest Basic): -2.7
Physiological Charge: 0
Hydrogen Acceptor Count: 2
Hydrogen Donor Count: 1
Polar Surface Area: 29.46 Ų
Rotatable Bond Count: 7

Refractivity: 42.38 m³·mol⁻¹
Polarizability: 18.54 ų
Number of Rings: 0
Bioavailability: 1
Rule of Five: Yes
Ghose Filter: Yes
Veber's Rule: Yes
MDDR-like Rule: Yes
S.G @ 20C/20C: 0.887
Distillation Range C Min: 200
Distillation Range C Max: 212
Evaporation Rate Ether = 1: >1200
Flash Point Deg C: 92
Solubility % wt in Water: @ 20C 1

Appearance and properties: transparent liquid
Density: 0.888 g/mL at 20 °C(lit.)
Boiling point: 98-99°C 0,15mm
Melting point: -45.1ºC
Flash point: 98-99°C/0.15mm
Refractive index: n20/D 1.431
Appearance: Colorless Clear Liquid
Content, GC%Wt: ≥98.0
Acidity,%Wt.(calculated as acetic acid): ≤0.01
Moisture,%Wt: ≤0.15
Chroma, Hazen unit (platinum-cobalt color number): ≤15
Min. Purity Spec: >99% (GC)
Physical Form (at 20°C): Liquid
Melting Point: -42°C

Boiling Point: 208°C
Flash Point: 94°C
Density: 0.89
Refractive Index: 1.43
Long-Term Storage: Store long-term in a cool, dry place
Appearance Form: liquid
Color: colorless
Odor: ether-like
Odor Threshold: No data available
pH: No data available
Melting point/freezing point:
Melting point/range: -50,1 °C at 1.013 hPa
Initial boiling point and boiling range: 208,5 °C at 1.013 hPa

Flash point: 90 °C - closed cup
Evaporation rate: No data available
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits: No data available
Vapor pressure: 0,1 hPa at 22,9 °C - OECD Test Guideline 104
Vapor density: No data available
Density: 0,888 g/mL at 20 °C
Relative density: No data available
Water solubility: 9,46 g/l - soluble
Partition coefficient: n-octanol/water:
log Pow: 1,97 at 25 °C
Autoignition temperature: 225 °C at 1.008 - 1.015 hPa
Decomposition temperature: No data available

Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 4,4 mPa.s at 20 °C
Explosive properties: No data available
Oxidizing properties: none
Other safety information: No data available
Appearance (20°)C : Clear Liquid
Color (APHA or less) : 15
Specific gravity (20°C) : 0.887～0.892
Acidity (% or less) : 0.01
Water content (% or less) : 0.2
Purity (% or more) : 98
Molecular Weight: 146.23
XLogP3: 1.9

Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 7
Exact Mass: 146.130679813
Monoisotopic Mass: 146.130679813
Topological Polar Surface Area: 29.5 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 55.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes


FIRST AID MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Remove contact lenses.
*If swallowed:
After swallowing: make victim drink water.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Take up carefully with liquid-absorbent material.
Dispose of properly.



FIRE FIGHTING MEASURES of ETHYLENE GLYCOL N-HEXYL ETHER:
-Extinguishing media:
*Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
-Further information:
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENE GLYCOL N-HEXYL ETHER:
-Control parameters
--Ingredients with workplace control parameters
-Exposure controls
--Personal protective equipment
*Eye/face protection
Use equipment for eye protection.
Tightly fitting safety goggles.
*Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Wash and dry hands.
*Body Protection:
protective clothing
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENE GLYCOL N-HEXYL ETHER:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Keep in a well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Store under inert gas.



STABILITY and REACTIVITY of ETHYLENE GLYCOL N-HEXYL ETHER:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature).
Stable under recommended storage conditions.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
2-(hexyloxy)ethan-1-ol
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
CAS-112-25-4
Ethylene glycol-n-monohexyl ether
HSDB 5569
EINECS 203-951-1
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383 (Beilstein Handbook Reference)
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
EN300-114321
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
2-(Hexyloxy)ethanol
Hexylglycol
2-(HEXYLOXY)ETHANOL
2-N-(HEXYLOXY)ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYLGLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethano
2-Hexoxyethanol
2-hexyloxy-ethano
Cellosolve, n-hexyl-
ethyleneglycol-n-monohexylether
Glycol monohexyl ether
glycolmonohexylether
Hexyl cellosolve
hexylcellosolve
n-hexyl-cellosolv
Ethylenegylcolmono-N-hexylether
2-(Hexyloxy)ethanol
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
2-Hexyloxy-1-ethanol
Ethylene glycol n-hexyl ether
2-n-(Hexyloxy)ethanol
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DSSTox_CID_6908
DSSTox_RID_78248
DSSTox_GSID_26908
31726-34-8
Ethanol, 2-hexyloxy-
Ethylene glycol-n-monohexyl ether
HSDB 5569
Hexyl alcohol, ethoxylated
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
Ethylene glycol hexyl ether
SCHEMBL24741
4-01-00-02383
CHEMBL3188016
DTXSID1026908
Poly(oxy-1,2-ethanediyl), .alpha.-hexyl-.omega.-hydroxy-
ZINC2041054
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
DB-041064
FT-0631642
H0343
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)
2-(Hexyloxy)ethanol
Cellosolve, n-hexyl-
Ethanol, 2-hexyloxy-
Ethylene glycol monohexyl ether
Ethylene glycol n-hexyl ether
Ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
Hexyl cellosolve
n-Hexyl cellosolve
C6E1
HEXYLGLYCOL
2-hexyloxyethanol
N-HEXYL CELLOSOLVE
2-(hexyloxy)-ethano
N-HEXYLMONOOXYETHYLENE
ETHYLENE GLYCOL N-HEXYL ETHER
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
2-(Hexyloxy)ethanol;2-HEXOXYETHANOL
AC1L1QF7
AC1Q7D9E
Cellosolve, N-hexyl-
EGHE
Ethanol, 2-(hexyloxy)-
Ethanol, 2-hexyloxy-
Ethylene glycol monohexyl ether
Ethylene glycol n-hexyl ether
Ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
H0343
Hexyl alcohol, ethoxylated
Hexyl cellosolve
Hexyl poly(oxyethylene) ether
Hexylglycol
Poly(oxy-1,2-ethanediyl), alpha-hexyl-omega-hydroxy-
SBB060173
alpha-Hexyl,omega-hydroxypoly(oxy-1,2-ethanediyl)
n-Hexyl cellosolve
2- (HEXYLOXY) ETHANOL
2-N-(HEXYLOXY) ETHANOL
C6E1
ETHYLENE GLYCOL MONOHEXYL ETHER
ETHYLENE GLYCOL MONO-N-HEXYL ETHER
ETHYLENE GLYCOL N-HEXYL ETHER
HEXYL GLYCOL
N-HEXYL CELLOSOLVE
N-HEXYLMONOOXYETHYLENE
2-(hexyloxy)-ethane
2-Hexoxyethanol
2-hexyloxy-ethano
Cell fluid, n-hexyl-
ethylene glycol-n-monohexyl ether
Glycol monohexyl ether
glycol monohexyl ether
Hexyl cellosolvation
hexyl cellosolve
n-hexyl-cellosolv
Ethylene gyl carbon mono-N-hexyl ether
Diethylene glycol hexyl ether
2-((2-Hexyloxy)ethoxy)ethanol
Diethylene glycol mono(n-hexyl) ether
Hexol carbitol
Diethylene glycol monohexyl ether
n-Hexoxyethoxyethanol
n-Hexyl carbitol
2-((2-Hexyloxy)ethoxy)ethanol
2-(2-(hexyloxy)ethoxy)ethanol

Ethylene glycol n-hexyl ether is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.
Ethylene glycol n-hexyl ether is typically a clear, colorless liquid with a characteristic mild odor.
Ethylene glycol n-hexyl ether is miscible with water and many organic solvents.

CAS Number: 112-25-4
Molecular Formula: C8H18O2
Molecular Weight: 146.23
EINECS Number: 203-951-1

Ethylene glycol n-hexyl ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Ethylene glycol n-hexyl ether is used as high-boiling solvent.
Ethylene glycol n-hexyl ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.

Ethylene glycol n-hexyl ether serves as a coalescing agent in cleaners and latex paints.
Ethylene Glycol n-Hexyl Ether's molecular formula is C8H18O2 or C6H13OCH2CH2OH.
Ethylene Glycol n-Hexyl Ether is a high boiling pint, slow evaporating rate solvent with excellent solvency characteristics.

Ethylene glycol n-hexyl ether is an oily colorless liquid with a mild sweet odor.
Ethylene glycol n-hexyl ether, also known as 1,6-Hexanediol, is a chemical compound with the molecular formula C6H14O2.
Ethylene glycol n-hexyl ether is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).

Ethylene Glycol n-Hexyl Ether or 2-(Hexyloxy)ethanol is a glycol ether.
Ethylene Glycol n-Hexyl Ether has a chemical formula of C6H14O2.
Ethylene Glycol n-Hexyl Ether is used as solvents in specialty printing inks and coalescing aids in surface coatings.

The chemical structure consists of a hexyl chain (a six-carbon linear alkyl group) attached to the oxygen atom of an ethylene glycol molecule.
Ethylene Glycol n-Hexyl Ether floats and mixes slowly with water.
Ethylene Glycol n-Hexyl Ether belongs to the class of diols, which are organic compounds containing two hydroxyl (-OH) groups.

The "n" in N-Hexyl Glycol indicates that the carbon chain is linear.
Ethylene Glycol n-Hexyl Ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Ethylene Glycol n-Hexyl Ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.

Ethylene Glycol n-Hexyl Ether's miscibility with water, however, is limited.
Ethylene Glycol n-Hexyl Ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
Since Ethylene Glycol n-Hexyl Ether may react with the oxygen in the air to form peroxides, BASF supplies it inhibited with 2.6-di-tert-butyl-paracresol Ethylene Glycol n-Hexyl Ether is as a solvent for coatings and degreasing.

Ethylene Glycol n-Hexyl Ether is mainly used as a solvent, flow promoter and coalescent aid in the coatings industry.
Ethylene Glycol n-Hexyl Ether is often referred to by common names such as hexyl cellosolve or hexyl glycol ether.
Ethylene Glycol n-Hexyl Ether finds applications in various industries, including coatings, paints, cleaning products, and as a solvent in different formulations.

Ethylene Glycol n-Hexyl Ether exhibits solvent properties, making it useful in formulations where solubility and dispersing properties are required.
Ethylene Glycol n-Hexyl Ether is commonly used as a solvent in the formulation of coatings and paints, where it aids in achieving the desired viscosity and flow properties.
Ethylene Glycol n-Hexyl Ether may be included in the formulation of cleaning products, such as degreasers and industrial cleaners.

Ethylene Glycol n-Hexyl Ether can be employed as a solvent in the production of inks, contributing to the dispersion of pigments and other ink components.
Ethylene Glycol n-Hexyl Ether is utilized in surface coatings for its ability to improve film formation and enhance the quality of the coating.
Ethylene Glycol n-Hexyl Ether may be used in certain chemical reactions or processes where its unique chemical properties are beneficial.

Ethylene Glycol n-Hexyl Ether is important to handle ethylene glycol n-hexyl ether with care and follow safety guidelines.
This includes using appropriate personal protective equipment and ensuring proper ventilation in areas where it is used.
Ethylene Glycol n-Hexyl Ether is used in printing inks and cleaners.

Ethylene Glycol n-Hexyl Ether is an oxygenated solvent derived from acetone which has two alcohol functions.
Ethylene Glycol n-Hexyl Ether has a low evaporation rate and it is completely miscible with water.
Ethylene Glycol n-Hexyl Ether is mainly used as a solvent or coupling agent.

Ethylene Glycol n-Hexyl Ether is a potential substitute for glycol ethers.
Ethylene Glycol n-Hexyl Ether is also an effective shrinkage reduction admixture or SRA for concrete and mortar.
Ethylene Glycol n-Hexyl Ether is often used in cosmetics and personal care products for its moisturizing properties.

Ethylene Glycol n-Hexyl Ether can contribute to the hydration of the skin when included in formulations such as creams and lotions.
In the flavor and fragrance industry, Ethylene Glycol n-Hexyl Ether can be utilized as a carrier for certain flavors and fragrances.
Ethylene Glycol n-Hexyl Ether is mild odor and solvency make it suitable for use in these applications.

Ethylene Glycol n-Hexyl Ether can be esterified with various acids to produce specific esters.
Esters derived from Ethylene Glycol n-Hexyl Ether may find use in different industries, including the fragrance and flavor industry.
Ethylene Glycol n-Hexyl Ether has been used historically in the production of photographic chemicals.

Ethylene Glycol n-Hexyl Ether also can be used as a coupling agent, rust remover, adhesives and surface cleaners.
Ethylene glycol n-hexyl ether, also known as hexyl cellosolve or hexyl glycol ether, is a chemical compound belonging to the family of glycol ethers.
Ethylene Glycol n-Hexyl Ether is characterized by having a six-carbon linear alkyl chain (hexyl) and an ethylene glycol moiety.

Ethylene Glycol n-Hexyl Ether is soluble in alcohol and ether, water (9.46 g/L ).
Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used as solvent in specialty printing inks, coalescent for water-borne latex-based coatings, primary solvent in solvent-based silk screen printing inks.

Ethylene Glycol n-Hexyl Ether possesses high boiling point.
Ethylene Glycol n-Hexyl Ether exhibits very good solvency, superior oil solubility, and slow evaporation rate.
Ethylene Glycol n-Hexyl Ether is a solvent.

Ethylene Glycol n-Hexyl Ether can be found in a variety of rust removers, hard surface cleaners and disinfectants.
Ethylene Glycol n-Hexyl Ether is used to break down soils and grease stains.
Ethylene Glycol n-Hexyl Ether or 2-(Hexyloxy)ethanol is a glycol ether.

Ethylene Glycol n-Hexyl Ether is used as solvents in specialty printing inks and coalescing aids in surface coatings.
Ethylene Glycol n-Hexyl Ether might be included in the formulation of adhesives and sealants, contributing to the viscosity and performance of these products.
Ethylene Glycol n-Hexyl Ether may be used in the textile industry, where it can aid in the solubilization and application of dyes and other chemicals.

Ethylene Glycol n-Hexyl Ether could be used in formulations for cleaning and degreasing metals in industrial processes.
In the woodworking industry, ethylene glycol n-hexyl ether might be included in wood stains and finishes to improve application properties.
Ethylene Glycol n-Hexyl Ether also can be used as a rust remover.

Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used as high-boiling solvent.
Ethylene Glycol n-Hexyl Ether also serves as an intermediate for hexyloxyethyl phosphate.

Ethylene Glycol n-Hexyl Ether is miscible with water, soluble in ethanol, and soluble in most organic solvents.
Ethylene Glycol n-Hexyl Ether is an oily colorless liquid with a mild sweet odor.
Ethylene Glycol n-Hexyl Ether floats and mixes slowly with water.

Ethylene Glycol n-Hexyl Ether is a glycol in which the two hydroxy groups are at positions 2 and 4 of 2-methylpentane (isopentane).
Ethylene Glycol n-Hexyl Ether is a clear, mobile, neutral, slightly hygroscopic liquid with a mild odor.
Ethylene Glycol n-Hexyl Ether is miscible with all common solvents, e. g. alcohols, ketones, aldehydes, ethers, glycols and aromatic and aliphatic hydrocarbons.

Ethylene Glycol n-Hexyl Ether may be utilized in the formulation of hydraulic brake fluids.
Ethylene Glycol n-Hexyl Ether is properties can contribute to the fluid's ability to transfer pressure and resist high temperatures in braking systems.
In the oil and gas industry, Ethylene Glycol n-Hexyl Ether might be used in the formulation of certain chemicals for oilfield applications, such as drilling fluids or completion fluids.

Ethylene Glycol n-Hexyl Ether can be employed in the formulation of coolants for various cooling systems, helping to maintain proper thermal conditions in industrial processes or automotive engines.
Ethylene Glycol n-Hexyl Ether may serve as a solvent in the pharmaceutical industry for certain drug formulations where its properties are beneficial.
Ethylene Glycol n-Hexyl Ether might be used as a catalyst or co-catalyst in organic synthesis reactions, facilitating specific chemical transformations.

In the field of hydraulic fracturing (fracking), Ethylene Glycol n-Hexyl Ether may find applications in the formulation of fracking fluids used to fracture rocks and extract natural gas or oil.
Ethylene Glycol n-Hexyl Ether can be incorporated into water treatment formulations for cooling towers to prevent scale formation and corrosion.
Ethylene Glycol n-Hexyl Ether's miscibility with water, however, is limited.

Ethylene Glycol n-Hexyl Ether enters into the typical reactions of alcohols, e. g. esterification, etherification, oxidation and the formation of alcoholates.
As a result, Ethylene Glycol n-Hexyl Ether provides unique cleaning power for removal of both water-soluble and greasy (water insoluble) soils.
The linear Ethylene Glycol n-Hexyl Ether portion of this provides excellent oil solubility characteristics that make it useful in both consumer and industrial cleaner applications.

Ethylene Glycol n-Hexyl Ether plays an important role in specialty printing inks.
Because of its limited water solubility and slow evaporation, it can be used in formulations for the silk screen process to prevent premature setting of the ink

Melting point: -45.1℃
Boiling point: 98-99°C 0,15mm
Density: 0.888 g/mL at 20 °C(lit.)
vapor pressure: 10Pa at 20℃
refractive index: n20/D 1.431
Flash point: 98-99°C/0.15mm
storage temp.: -15°C
pka: 14.44±0.10(Predicted)
form: clear liquid
color: Colorless to Light yellow
Water Solubility: Soluble in alcohol and ether, water (9.46 g/L ).
BRN: 1734691
LogP: 1.97 at 25℃

Ethylene glycol n-hexyl ether is considered a VOC, and its use is regulated in certain applications due to environmental and air quality concerns.
In some regions, there are limits on the allowable VOC content in certain consumer products.
Ethylene Glycol n-Hexyl Ether may have film-forming properties, which can be beneficial in applications where the formation of a protective or decorative film is desired, such as in coatings and paints.

Similar to other glycol ethers, ethylene glycol n-hexyl ether may have hygroscopic properties, meaning it can absorb moisture from the air.
Ethylene Glycol n-Hexyl Ether can be used as a chemical intermediate in the synthesis of other compounds.
Some chemical reactions may involve the use of ethylene glycol n-hexyl ether as a starting material.

Due to its solvency, it may find applications in industrial cleaning processes, particularly in formulations designed to remove oils, greases, and other contaminants.
Ethylene Glycol n-Hexyl Ether is an oxygenated solvent derived from acetone which has two alcohol functions.
Ethylene Glycol n-Hexyl Ether is used as a reagent in the synthesis of functionalized boronic esters.

Ethylene Glycol n-Hexyl Ether is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.
Ethylene Glycol n-Hexyl Ether may find applications in heat transfer fluids, helping to transfer heat efficiently in various industrial processes.
Ethylene Glycol n-Hexyl Ether may be used in analytical chemistry as a solvent or as a component in certain analytical methods.

Ethylene Glycol n-Hexyl Ether is a member of the glycol ether family, which includes various compounds used in different industries for their solvency, stability, and other properties.
Ethylene Glycol n-Hexyl Ether also used in the preparation of vinylboronates.
Ethylene Glycol n-Hexyl Ether is mainly used as a coupling agent and an additive to hydraulic fluids, inks and cement.

Ethylene Glycol n-Hexyl Ether can also be used as a building block in chemical synthesis.
Ethylene Glycol n-Hexyl Etheris also employed as a blood volume expander.
Ethylene Glycol n-Hexyl Ether can be used in formulations for the silk screen process to prevent premature setting of the ink.

Ethylene Glycol n-Hexyl Ether may be used in the tire manufacturing industry as a component in adhesives for tire cord, contributing to the bonding properties of the adhesive.
Ethylene Glycol n-Hexyl Ether may be employed as an antioxidant in fuel formulations to help prevent degradation and improve the stability of the fuel.
Ethylene Glycol n-Hexyl Ether might be considered as a component in wood preservatives, helping to protect wood from decay and insect damage.

Ethylene Glycol n-Hexyl Ether may find applications in the production of materials used in the photovoltaic (solar cell) industry.
Ethylene Glycol n-Hexyl Ether may be used in research and development activities, particularly in laboratories exploring new formulations or chemical processes.
Ethylene Glycol n-Hexyl Ether can be employed in the polymer industry as a component in the synthesis of certain polymers.

Ethylene Glycol n-Hexyl Ether is inclusion may impart specific properties to the resulting polymer.
Ethylene glycol n-hexyl ether might find applications in the automotive industry, such as in the formulation of automotive coatings or cleaning products.
Due to its solvency and film-forming properties, it may be used in the formulation of floor polishes and waxes.

Ethylene Glycol n-Hexyl Ether could be included in formulations for ink removers or cleaning agents designed to remove ink stains.
In the textile printing industry, ethylene glycol n-hexyl ether may be used in ink formulations for printing on fabrics.
Ethylene Glycol n-Hexyl Ether might be used in the formulation of aerosol products, such as spray paints or coatings.

Ethylene Glycol n-Hexyl Ether is generally considered to be biodegradable.
Biodegradability is an important factor in assessing the environmental impact of a chemical.
Ethylene Glycol n-Hexyl Ether could be used in the production of resins, contributing to the overall characteristics of the resin.

Ethylene glycol n-hexyl ether may be employed in the formulation of certain hydraulic fluids, contributing to their lubricating properties.
In the field of inkjet printing, it may find applications in ink formulations for use in inkjet printers.

Ethylene Glycol n-Hexyl Ether is solvency properties make it suitable for use in formulations for metal degreasers, which are used to remove oils and greases from metal surfaces.
In laboratory settings, Ethylene Glycol n-Hexyl Ether might be used as a solvent or as a component in specific experimental setups.

Uses:
Ethylene Glycol n-Hexyl Ether is used as solvents in speciality printing inks and coalescing aids in surface coatings, coupling agent, rust remover, adhesives and surface cleaners.
Ethylene Glycol n-Hexyl Ether is used by professional workers (widespread uses), consumers, in re-packing or re-formulation, in manufacturing, and at industrial sites.
Ethylene Glycol n-Hexyl Ether is used as high-boiling solvent.

Ethylene Glycol n-Hexyl Ether also serves as an intermediate for neopentanoate and hexyloxyethyl phosphate.
Ethylene Glycol n-Hexyl Ether serves as a coalescing agent in cleaners and latex paint.
Ethylene Glycol n-Hexyl Ether can be used as solvent in specialty printing inks.

Ethylene Glycol n-Hexyl Ether can be used as coalescent for water-borne
Ethylene Glycol n-Hexyl Ether can be used as solvent in specialty printing inks.
Ethylene Glycol n-Hexyl Ether can be used as coalescent for water-borne.

Ethylene Glycol n-Hexyl Ether can be used as coupling agent and solvent in household and industrial clearners, rust removers, hard surface cleaners and disinfectants.
Ethylene Glycol n-Hexyl Ether is a fine chemical product with a wide range of uses, which can be used in pesticides, biochemical engineering, photosensitive materials, synthetic fragrances and other fields.
Ethylene Glycol n-Hexyl Ether is a highly soluble high-grade organic solvent.

Ethylene Glycol n-Hexyl Ether can be used as an additive in the production of metal surface treatment agents for rust and oil removal.
Ethylene Glycol n-Hexyl Ether can also be used as a textile auxiliaries, as well as coatings and latex paints.
Ethylene Glycol n-Hexyl Ether can also be used in cosmetics, as a pesticide stabilizer, but also as a daily chemical moisturizer, flavor and fragrance raw materials, hydraulic oil, high-temperature lubricating oil, brake oil, dry cleaning agent, printing ink, pigment dispersant, wood preservative etc.

Ethylene Glycol n-Hexyl Ether can be used as primary solvent in solvent-based silk screen printing inks.
Ethylene Glycol n-Hexyl Ether is used as a solvent in the formulation of coatings and paints to improve viscosity, flow, and film-forming properties.
Included in industrial cleaners and degreasers due to its solvency, helping to remove oils, greases, and contaminants.

Ethylene Glycol n-Hexyl Ether employed as a solvent in the production of inks for various printing applications, such as inkjet printing and textile printing.
Ethylene Glycol n-Hexyl Ether found in automotive coatings, cleaning products, and formulations where its solvent properties are beneficial.
Included in the formulation of adhesives and sealants, contributing to viscosity and performance.

Ethylene Glycol n-Hexyl Ether is used in the production of floor polishes and waxes, where it helps in achieving a smooth and protective finish.
Applied in the textile industry for solubilizing dyes and other chemicals used in fabric treatments.
Ethylene Glycol n-Hexyl Ether found in the formulation of aerosol products, including spray paints and coatings.

Ethylene Glycol n-Hexyl Ether is used in industrial processes for cleaning and degreasing metal surfaces.
Ethylene Glycol n-Hexyl Ether may find applications in the production of materials used in the photovoltaic (solar cell) industry.
Ethylene Glycol n-Hexyl Ether is used as a component in the synthesis of certain polymers, contributing specific properties to the final polymer.

Included in the formulation of hydraulic fluids or other automotive fluids where its properties are beneficial.
Ethylene Glycol n-Hexyl Ether employed in woodworking for improving the application properties of wood stains and finishes.
Ethylene Glycol n-Hexyl Ether is used in formulations for ink removers or cleaning agents designed to remove ink stains.

Ethylene Glycol n-Hexyl Ether found in ink formulations for textile printing on fabrics.
Considered biodegradable, making it suitable for applications where environmental impact is a concern.
Ethylene Glycol n-Hexyl Ether is used in the production of resins, contributing to the characteristics of the resin.
Hydraulic Fluids:

Ethylene Glycol n-Hexyl Ether is used in formulations for metal degreasers to remove oils and greases from metal surfaces.
Ethylene Glycol n-Hexyl Ether is used in laboratories as a solvent or a component in specific experimental setups where its properties are advantageous.
Ethylene Glycol n-Hexyl Ether may be utilized as a component in fuel additives to enhance stability and performance.

Ethylene Glycol n-Hexyl Ether found in the formulation of coolants and heat transfer fluids where it helps maintain proper thermal conditions.
Ethylene Glycol n-Hexyl Ether included as a component in wood preservatives to protect wood from decay and insect damage.
Ethylene Glycol n-Hexyl Ether is used in the production of surfactants where its properties contribute to the stability of emulsions or foams.

Ethylene Glycol n-Hexyl Ether is used in the formulation of deicing fluids, particularly in applications where prevention of ice formation is crucial.
Included as an additive in concrete formulations to improve workability and setting time.
Utilized in the oil and gas industry for the formulation of certain chemicals used in oilfield applications.

Ethylene Glycol n-Hexyl Ether may be used in the formulation of hydraulic brake fluids for automotive applications.
Ethylene Glycol n-Hexyl Ether is used as a reagent in the synthesis of functionalized boronic esters.
Ethylene Glycol n-Hexyl Ether is used in laboratory studies as a precipitant and cryoprotectant in protein crystallography.

Ethylene Glycol n-Hexyl Ether is used as a carrier for certain flavors and fragrances in the flavor and fragrance industry.
Ethylene Glycol n-Hexyl Ether found in the formulation of metalworking fluids, providing lubrication and cooling during machining processes.
Ethylene Glycol n-Hexyl Ether is used as an additive in concrete formulations to improve workability and setting time.

Safety profile:
According to the European Chemicals Agency, Ethylene Glycol n-Hexyl Ether is classified as harmful when in contact with skin and when swallowed.
Ethylene Glycol n-Hexyl Ether can also cause skin burns and serious eye damage.
Ethylene Glycol n-Hexyl Ether was also known to cause kidney injury and depression.

Ethylene Glycol n-Hexyl Ether is also a severe respiratory tract irritant.
Ethylene Glycol n-Hexyl Ether may also have blood effects.
Ethylene Glycol n-Hexyl Ether may enter the body through ingestion, aerosol inhalation, and through the skin.

Ethylene Glycol n-Hexyl Ether may form explosive peroxides.
Ethylene Glycol n-Hexyl Ether can react violently with strong oxidants.
Ethylene Glycol n-Hexyl Ether is classified as a green circle product EPA Safer Choice meaning it is of low concern.

Ethylene glycol n-hexyl ether may cause irritation to the skin and eyes upon contact.
Ethylene Glycol n-Hexyl Ether is important to use appropriate personal protective equipment, such as gloves and safety goggles, to prevent direct contact.
Inhalation of vapors or mists of ethylene glycol n-hexyl ether may cause respiratory irritation.

Adequate ventilation should be maintained in areas where it is used, and respiratory protection may be necessary.
Ingesting ethylene glycol n-hexyl ether can be harmful.

Ethylene Glycol n-Hexyl Ether is not intended for consumption, and ingestion may lead to adverse health effects.
While not highly flammable, ethylene glycol n-hexyl ether may pose a fire hazard under certain conditions.
Precautions should be taken to prevent ignition sources in areas where it is handled.

Synonyms:
2-(Hexyloxy)ethanol
112-25-4
Ethylene glycol monohexyl ether
2-Hexyloxyethanol
Ethanol, 2-(hexyloxy)-
2-HEXOXYETHANOL
Hexyl cellosolve
n-Hexyl cellosolve
Glycol monohexyl ether
Cellosolve, N-hexyl-
Ethylene glycol n-hexyl ether
2-Hexyloxy-1-ethanol
DTXSID1026908
7P0O8282NR
Ethylene glycol mono-n-hexyl ether
DTXCID606908
Ethanol, 2-hexyloxy-
2-(hexyloxy)ethan-1-ol
CAS-112-25-4
Ethylene glycol-n-monohexyl ether
HSDB 5569
2-n-(Hexyloxy)ethanol
EINECS 203-951-1
BRN 1734691
UNII-7P0O8282NR
2-hexyloxy-ethanol
MFCD00045997
2-(n-Hexyloxy)ethanol
Ethylenglykolmonohexylether
2-(1-Hexyloxy) ethanol
EC 203-951-1
SCHEMBL24741
31726-34-8
4-01-00-02383 (Beilstein Handbook Reference)
CHEMBL3188016
Tox21_202105
Tox21_300545
AKOS009156771
NCGC00248089-01
NCGC00248089-02
NCGC00254448-01
NCGC00259654-01
LS-13544
FT-0631642
H0343
EN300-114321
F71224
W-109065
Q27268660
Ethylene glycol monohexyl ether, BioXtra, >=99.0% (GC)

SYNONYMS Ethylene Glycol Carbonate; 1,3-dioxolan-2-one;Glycol Carbonate; Dioxolone-2; Cyclic Ethylene Carbonate; Ethylene Carbonic Acid; Carbonic Acid, Cyclic Ethylene Ester; CAS NO:96-49-1

CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O


DESCRIPTION:
2-Imidazolidone (Ethylene Urea) is a white crystalline powder, which can be dissolved in water.
Ethylene urea serves mainly as a formaldehyde scavenger and chemical building block.
Apart from the textile industry Ethylene urea is used in construction and coatings industry applications.
The Ethylene Urea 87% - also known as 2-Imidazolidinone hemihydrate – is mainly used in various kinds of formaldehyde removing formulations such as high-effect formaldehyde removing detergents and long-term formaldehyde dissolution intermediates.
In the flavor and fragrance industry the product is used as a release control agent.
The pharma industry is using the product as an intermediate for antibiotics such as Mezlocillin and Azlocillin.


Ethylene urea is an organic compound derived from formaldehyde and urea.
Ethylene urea is a colourless solid that is used for treating cellulose-based heavy fabrics to inhibit wrinkle formation.
Ethylene urea (DMEU) bonds with the hydroxyl groups present in long cellulose chains and prevents the formation hydrogen bonding between the chains, the primary cause of wrinkling.

This treatment produces permanently wrinkle-resistant fabrics and is different from the effects achieved from using fabric softeners.
An additional names for Ethylene urea includes 1,3-bis(hydroxymethyl)-tetrahydro-2-imidazolone


Main users are the leather, rubber, fragrance and textile coating industry.

APPLICATIONS OF ETHYLENE UREA:
• Textile auxiliaries
• Fragrance
• Pharma
Ethylene urea can be very affective at scavenging formaldehyde in various resin systems.
Reduction of 75% can be achieved depending on application conditions and the resin system properties.
The exact amount needed would depend on many variables, but laboratory experimentation should be performed to establish optimized dosage.
1. Textile industry
Cotton products are composed by long chain cellulose, which contains lots of hydroxyls to form spacious hydrogen bonds.
These hydrogen bonds will be broken and then randomly reformed under the heat or external forces. That’s how the fabric folds come.

2-Imidazolidone (Ethylene Urea) reacts with hydroxyl groups when treating fabrics together with formaldehyde, forming a stable structure to prevent the folds from forming.
This method can also restain the pungent odor caused from using formaldehyde only as the anti-wrinkle treatment by effectively inhibiting the release of formaldehyde.

Besides, urea resin is another widely used textile finishing agent.
Its residues on fabrics slowly release formaldehyde, which can be effectively inhibited by 2-Imidazolidone (Ethylene Urea).

Coating and Paint:
2-Imidazolidone (Ethylene Urea) can be used as de-aldehyde agent in poly-EVA, all kinds of water-based coatings, paints, pigments, adhesives and paper industry.
Ethylene Urea can also be added to the paint alone to make the paint absorbing and decomposing formaldehyde.

Ink for inkjet printers:
2-Imidazolidone (Ethylene Urea) is an important additives of ink for inkjets.
Ethylene Urea can disperse the pigment, lubricate the channels, prevent nozzles from drying out and blocking, and imporve the storage stability of ink.
Ethylene Urea can also imporve the color contrast to enhance the printing effect.

Adhesive:
Various types of artificial panels such as plywood, chipboard, fiberboard and composite panels, usually choose urea resin, phenolic resin or melamine resin as adhesives.
Those adhesives are produced from polycondensation between formaldehyde and urea, phenol or melamine respectively.
All of them have the problem of slowly releasing gaseous formaldehyde into the environment.
2-Imidazolidone (Ethylene Urea) can be added to effectively reduce the formaldehyde release and does not affect the bonding effect.

Daily Chemical:
2-Imidazolidone (Ethylene Urea) is the main composition of household de-aldehyde agent.
Ethylene Urea can be used as high-performance formaldehyde remover, home air formaldehyde potent enzyme, formaldehyde long-acting melting medium, aldehyde remover for glue, photocatalyst, floor deodorization care wax, furniture deodorizer, car deodorizer, etc.

Organic Synthesis:
2-Imidazolidone (Ethylene Urea) can be used as intermediates of many new antibiotics, such as meloxicillin and aloxicillin, as intermediates for anti-schistosomiasis drugs, and as basic raw materials of third-generation penicillin.
In the biological field, Ethylene Urea can be used to produce the plant growth regulators, fungicides, inhibitors, herbicides, etc., such as: N-chlorocarbonyl-2-imidazolidinone, 1-chlorocarbonyl-3-acetyl-2-imidazolidinone, 1-chlorocarbonyl-3-methanesulfonyl-2-imidazolidinone N-chloroformyl-2-imidazolidinone, 1-chloroformyl-3-acetyl-2-imidazolidinone, 1-chloroformyl-3-methanesulfonyl-2-imidazolidinone, N-hydroxyethyl-2-imidazolidinone, 1-methanesulfonyl-2-imidazolidinone, 1,3-dimethyl-2-imidazolidinone, 1-acetyl-2-imidazolidinone, etc




CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O




USES OF ETHYLENE UREA:
Ethylene urea is an organic intermediate used in various chemical industries.
Ethylene urea was originally used for the production of dimethylol ethylene urea thermosetting resins in textiles and paper.
Ethylene urea is also used as a scavenging agent to reduce the free formaldehyde in phenolic, melamine, glyoxal and urea formaldehyde resin systems for the coatings, construction and textile industries.

STORAGE CONDITIONS OF ETHYLENE UREA:
Ethylene urea has a shelf life of at least twelve months from the date of delivery; if stored in original unopened containers at temperatures not exceeding 30°C (86°F).
Continued storage beyond the designated shelf life does not necessarily mean the material cannot be used.
However, renewed testing of the most important properties is imperative.





CHEMICAL AND PHYSICAL PROPERTIES OF ETHYLENE UREA:
Molecular Weight: 86.09
XLogP3: -1.3
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 1
Rotatable Bond Count: 0
Exact Mass: 86.048012819
Monoisotopic Mass: 86.048012819
Topological Polar Surface Area: 41.1 Ų
Heavy Atom Count: 6
Formal Charge: 0
Complexity: 63.2
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Appearance: Clear Liquid
Color (APHA): <150
pH (neat): 6.0 to 7.0
Viscosity (cps): <100
Density (lbs / gal): 9.0 to 9.26


CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O

SAFETY INFORMATION ABOUT ETHYLENE UREA:

First aid measures:
Description of first aid measures:
General advice:
Consult a physician.
Show this safety data sheet to the doctor in attendance.
Move out of dangerous area:

If inhaled:
If breathed in, move person into fresh air.
If not breathing, give artificial respiration.
Consult a physician.
In case of skin contact:
Take off contaminated clothing and shoes immediately.
Wash off with soap and plenty of water.
Consult a physician.

In case of eye contact:
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
Continue rinsing eyes during transport to hospital.

If swallowed:
Do NOT induce vomiting.
Never give anything by mouth to an unconscious person.
Rinse mouth with water.
Consult a physician.

Firefighting measures:
Extinguishing media:
Suitable extinguishing media:
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas

Advice for firefighters:
Wear self-contained breathing apparatus for firefighting if necessary.
Accidental release measures:
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment.

Avoid breathing vapours, mist or gas.
Evacuate personnel to safe areas.

Environmental precautions:
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up:
Soak up with inert absorbent material and dispose of as hazardous waste.
Keep in suitable, closed containers for disposal.

Handling and storage:
Precautions for safe handling:
Avoid inhalation of vapour or mist.

Conditions for safe storage, including any incompatibilities:
Keep container tightly closed in a dry and well-ventilated place.
Containers which are opened must be carefully resealed and kept upright to prevent leakage.
Storage class (TRGS 510): 8A: Combustible, corrosive hazardous materials

Exposure controls/personal protection:
Control parameters:
Components with workplace control parameters
Contains no substances with occupational exposure limit values.
Exposure controls:
Appropriate engineering controls:
Handle in accordance with good industrial hygiene and safety practice.
Wash hands before breaks and at the end of workday.

Personal protective equipment:
Eye/face protection:
Tightly fitting safety goggles.
Faceshield (8-inch minimum).
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection:
Handle with gloves.
Gloves must be inspected prior to use.
Use proper glove
removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.

Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:Dermatril (KCL 740 / Aldrich Z677272, Size M)
It should not be construed as offering an approval for any specific use scenario.

Body Protection:
Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection:
Where risk assessment shows air-purifying respirators are appropriate use a fullface respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls.

If the respirator is the sole means of protection, use a full-face supplied air respirator.
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so.
Do not let product enter drains.
Discharge into the environment must be avoided.

Stability and reactivity:
Chemical stability:
Stable under recommended storage conditions.
Incompatible materials:
Strong oxidizing agents:
Hazardous decomposition products:
Hazardous decomposition products formed under fire conditions.
Carbon oxides, Nitrogen oxides (NOx), Hydrogen chloride gas.

Disposal considerations:
Waste treatment methods:
Product:
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging:
Dispose of as unused product.





CAS No.: 120-93-4
EC No.: 204-436-4
Molecular Weight: 86.09 g/mol
IUPAC Name: imidazolidin-2-one
Molecular Formula: C3H6N2O






SYNONYMS OF ETHYLENE UREA:
MeSH Entry Terms:
2-imidazolidinone
ethylene urea
imidazolidin-2-one

Depositor-Supplied Synonyms:
2-Imidazolidone
imidazolidin-2-one
120-93-4
2-Imidazolidinone
ETHYLENEUREA
imidazolidinone
Ethylene urea
N,N'-Ethyleneurea
2-Oxoimidazolidine
1,3-Ethyleneurea
Imidazolid-2-one
Monoethyleneurea
2-Oxomidazolidine
Urea, 1,3-ethylene-
SD 6073
2-imidazolidinon
Urea, N,N'-(1,2-ethanediyl)-
NSC 21314
CHEBI:37001
Urea,3-ethylene-
NSC-21314
WLN: T5MVMTJ
2K48456N55
Urea,N'-(1,2-ethanediyl)-
HSDB 4021
EINECS 204-436-4
imidazolidone
2-imidazolinone
AI3-22151
imidazolin-2-one
UNII-2K48456N55
Imidazoliden-2-one
2-oxo-imidazolidine
MFCD00005257
2-Imidazolidone, 96%
DSSTox_CID_602
EC 204-436-4
ETHYLENEUREA [HSDB]
DSSTox_RID_75683
DSSTox_GSID_20602
CHEMBL12034
IMIDAZOLIDINONE [INCI]
2-IMIDAZOLIDINONE [MI]
DTXSID0020602
NSC3338
NSC-3338
NSC21314
ZINC1666720
Tox21_200783
AKOS000121325
7-Benzyloxy-1H-indole-3-carboxylicacid
NCGC00248832-01
NCGC00258337-01
AS-13128
BP-21148
CAS-120-93-4
DB-021217
DB-021218
AM20080146
CS-0075560
FT-0626340
FT-0668259
I0005
EN300-21266
D71145
2-Imidazolidinon 100 microg/mL in Acetonitrile
A804620
2-Imidazolidone, PESTANAL(R), analytical standard
Q-200290
Q2813813
F0001-0335
Z104494954

SYNONYMS 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA;Ethane-1,2-diamine; Aethaldiamin (German); Aethylenediamin (German); 1,2-diaminoaethan (German) ; 1,2-Diamino-ethaan (Dutch); 1, 2-Diamino-Ethano (Italian); Dimethylenediamine; Ethyleendiamine (Dutch); Ethylene-diamine (French); β-Aminoethylamine; 乙二胺 (Chinese) CAS NO:107-15-3

ETHYLENEDIAMINE = EDA

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
This colorless liquid with an ammonia-like odor is a basic amine.
Ethylenediamine is the first member of the so-called polyethylene amines.

CAS Number: 107-15-3
EC Number: 203-468-6
Chemical Formula: H2NCH2CH2NH2
Molar Mass: 60.10 g/mol

EDA is used as a building block for the synthesis of bleach activators, chelates and crop protection products.
Furthermore is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.

Ethylenediamine is chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from EDA are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.

Polyamide resins find wide use as binders in printing inks for flexogravure application on certain paper, film, and foil webs and in hot-melt, pressure-sensitive, and heat-seal adhesives for leather, paper, plastic, and metal.
The main polyamide resin type, in addition to the liquid resins used as epoxy hardeners, is prepared generally by the condensation reaction of diamines with di- and polybasic fatty acids.

Thermoplastic polyamides are similarly used in formulating glossy, abrasion-resistant, overprint varnishes.
EDA is available as pure substance.

Ethylenediamine is a single-component product with two primary nitrogens.
Ethylenediamine has an ammonia-like odor and is clear and colorless.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.

Ethylenediamine is an inflammable substance.
Ethylenediamine reacts severely to aldehyde and acids.

Ethylenediamine absorbs the carbon dioxide in the air.
Ethylenediamine is hygroscopic and resolves in water, ether, benzene, acetone and hexane.

Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.
This colorless liquid with an ammonia-like odor is a basic amine.

Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine is the first member of the so-called polyethylene amines.

Ethylenediamine (EDA) is the ethyleneamine with the lowest molecular weight.
Ethylenediamine contains two primary amine groups and is a colorless liquid.
Ethylenediamine is commonly used as an intermediate to produce detergents, chelates, textile auxiliaries, agrochemicals and polyamides.

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.

Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to ethylenediamine may be identified with a clinical patch test.

Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.
Ethylenediamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor.
Ethylenediamine is flash point of 91 °F and a melting point of 47 °F.

Ethylenediamine is corrosive to tissue.
Ethylenediamine is vapors are heavier than air.

Ethylenediamine is produces toxic oxides of nitrogen during combustion.
Ethylenediamine is density 7.5 lb / gal.
Ethylenediamine is used to make other chemicals and as a fungicide.

Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine has a role as a GABA agonist.
Ethylenediamine derives from a hydride of an ethane.

Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.

Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to ethylenediamine may be identified with a clinical patch test.

Usage Area of Ethylenediamine:
Ethylenediamine is used in the textile sector.
Ethylenediamine is used the fields of fiber, polyamide and rubber.

Ethylenediamine is used as a chelator and a corrosion inhibitor.
Ethylenediamine is used as a lubricant in the plastics sector.
Ethylenediamine is used in foam making operations.

Uses of Ethylenediamine:
Ethylenediamine is used in the manufacture of chelating agents, fungicides, waxes, polyamide resins, and corrosion inhibitors.
Ethylenediamine is used as an emulsifier, an inhibitor in antifreeze solutions, and an additive to pharmaceuticals and textile lubricants.

Ethylenediamine is used in photography (color developing baths).
Ethylenediamine is used in prepn of dyes, synthetic waxes, resins, insecticides and asphalt wetting agents.

Drug Indication:
Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.

Widespread uses by professional workers:
Ethylenediamine is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.
Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
Other release to the environment of Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

Uses at industrial sites:
Ethylenediamine is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.
Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).

Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine is used for the manufacture of: chemicals.
Release to the environment of Ethylenediamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.

Industry Uses:
Hardener
Intermediate
Intermediates
Processing aids, specific to petroleum production
Soil amendments (fertilizers)

Industrial Processes with risk of exposure:
Textiles (Fiber & Fabric Manufacturing)
Painting (Pigments, Binders, and Biocides)
Photographic Processing

Other Uses of Ethylenediamine:
Corrosion inhibitors
Wet-strength resins
Fabric softeners
Epoxy curing agents
Polyamide resins
Fuel additives
Lube oil additives
Asphalt additives
Ore flotation
Corrosion inhibitors
Ore flotation
Asphalt
Additives
Corrosion inhibitors
Epoxy curing agents
Hydrocarbon purification
Lube oil & fuel additives
Mineral processing aids
Polyamide resins
Surfactants
Textile additives-paper wet-strength resins
Fabric softeners
Surfactants
Coatings
Urethanes
Fuel additives
Chemical intermediates
Epoxy curing agents
Lube oils
Wet strength resins

Applications of Ethylenediamine:
Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.
Because of Ethylenediamine bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.

Precursor to chelation agents, drugs, and agrochemicals:
A most prominent derivative of ethylenediamine is the chelating agent EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde.
Hydroxyethylethylenediamine is another commercially significant chelating agent.

Numerous bio-active compounds and drugs contain the N-CH2-CH2-N linkage, including some antihistamines.
Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brand names Maneb, Mancozeb, Zineb, and Metiram.
Some imidazoline-containing fungicides are derived from ethylenediamine.

Pharmaceutical Ingredient:
Ethylenediamine is an ingredient in the common bronchodilator drug aminophylline, where Ethylenediamine serves to solubilize the active ingredient theophylline.
Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.

When used as a pharmaceutical excipient, after oral administration Ethylenediamine bioavailability is about 0.34, due to a substantial first-pass effect.
Less than 20% is eliminated by renal excretion.

Ethylenediamine-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline.
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)

Role in Polymers:
Ethylenediamine, because Ethylenediamine contains two amine groups, is a widely used precursor to various polymers.
Condensates derived from formaldehyde are plasticizers.

Ethylenediamine is widely used in the production of polyurethane fibers.
The PAMAM class of dendrimers are derived from ethylenediamine.

Tetraacetylethylenediamine:
The bleaching activator tetraacetylethylenediamine is generated from ethylenediamine.
The derivative N,N-ethylenebis(stearamide) (EBS) is a commercially significant mold-release agent and a surfactant in gasoline and motor oil.

Other Applications:
As a solvent, Ethylenediamine is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.

As a corrosion inhibitor in paints and coolants.
Ethylenediamine dihydroiodide (EDDI) is added to animal feeds as a source of iodide.

Chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
As a compound to sensitize nitromethane into an explosive.
This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.

Benefits of Ethylenediamine:
Consistent and predictable reaction products
Easily derivatized
Low vapor pressure
High viscosity
Low environmental impact
Suitable for harsh conditions
Low sensitivity
Versatile

Functions of Ethylenediamine:
Raw Material,
Scale inhibitor,
Chemical Intermediate,
Chemical Reagent,
Dispersing Agent,
Scale Removal and Control

Human Metabolite Information of Ethylenediamine:

Tissue Locations:
Kidney
Liver

Cellular Locations:
Cytoplasm
Extracellular

Synthesis of Ethylenediamine:
Ethylenediamine is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.

In this reaction hydrogen chloride is generated, which forms a salt with the amine.
The amine is liberated by addition of sodium hydroxide and can then be recovered by rectification.
Diethylenetriamine (DETA) and triethylenetetramine (TETA) are formed as by-products.

Another industrial route to ethylenediamine involves the reaction of ethanolamine and ammonia.

This process involves passing the gaseous reactants over a bed of nickel heterogeneous catalysts.

Ethylenediamine can be produced in the lab by the reaction of ethylene glycol and urea.
Ethylenediamine can be purified by treatment with sodium hydroxide to remove water followed by distillation.

General Manufacturing Information of Ethylenediamine:

Industry Processing Sectors:
Agriculture, Forestry, Fishing and Hunting
All Other Basic Inorganic Chemical Manufacturing
All Other Basic Organic Chemical Manufacturing
All Other Chemical Product and Preparation Manufacturing
Not Known or Reasonably Ascertainable
Oil and Gas Drilling, Extraction, and Support activities
Paint and Coating Manufacturing
Petrochemical Manufacturing
Petroleum Refineries
Pharmaceutical and Medicine Manufacturing
Wholesale and Retail Trade

Coordination Chemistry of Ethylenediamine:
Ethylenediamine is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand.
Ethylenediamine is often abbreviated "en" in inorganic chemistry.

The complex [Co(ethylenediamine)3]3+ is an archetypical chiral tris-chelate complex.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.

Related ligands:
Related derivatives of ethylenediamine include ethylenediaminetetraacetic acid (EDTA), tetramethylethylenediamine (TMEDA), and tetraethylethylenediamine (TEEDA).
Chiral analogs of ethylenediamine include 1,2-diaminopropane and trans-diaminocyclohexane.

Handling and Storage of Ethylenediamine:

Nonfire Spill Response:
ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area.
All equipment used when handling the product must be grounded.

Do not touch or walk through spilled material.
Stop leak if you can do Ethylenediamine without risk.

Prevent entry into waterways, sewers, basements or confined areas.
A vapor-suppressing foam may be used to reduce vapors.

Absorb with earth, sand or other non-combustible material.
For hydrazine, absorb with DRY sand or inert absorbent (vermiculite or absorbent pads).
Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL:
Dike far ahead of liquid spill for later disposal.
Water spray may reduce vapor, but may not prevent ignition in closed spaces.

Safe Storage:
Separated from strong oxidants, acids, chlorinated organic compounds and food and feedstuffs.
Store only in original container.

Storage Conditions:
Outside or detached storage is preferred.
Avoid oxidizing materials, acids, and sources of halogens.
Store in a cool, dry, well-ventilated location.

Safety of Ethylenediamine:
Ethylenediamine, like ammonia and other low-molecular weight amines, is a skin and respiratory irritant.
Unless tightly contained, liquid ethylenediamine will release toxic and irritating vapors into Ethylenediamine surroundings, especially on heating.
The vapors absorb moisture from humid air to form a characteristic white mist, which is extremely irritating to skin, eyes, lungs and mucus membranes.

First Aid Measures of Ethylenediamine:
Exposure to ethylenediamine may result in cough, difficulty in breathing, irritation of the lungs, and pneumonia.
Nausea, vomiting, and diarrhea are often seen.
Contact with ethylenediamine may result in redness, pain, irritation, and burns.

Emergency Life-Support Procedures:
Exposure to ethylenediamine may require decontamination and life support for the victims.
Emergency personnel should wear protective clothing appropriate to the type and degree of contamination.

Air-purifying or supplied-air respiratory equipment should also be worn, as necessary.
Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air.
Emergency personnel should avoid self-exposure to ethylenediamine.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Transport to a health care facility.

Dermal/Eye Exposure:

1. Remove victims from exposure.
Emergency personnel should avoid self- exposure to ethylenediamine.

2. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

3. Remove contaminated clothing as soon as possible.

4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.

5. Thoroughly wash exposed skin areas with water for at least 15 minutes.

6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

7. Transport to a health care facility.

Ingestion Exposure:

1. Evaluate vital signs including pulse and respiratory rate, and note any trauma.
If no pulse is detected, provide CPR.

If not breathing, provide artificial respiration.
If breathing is labored, administer oxygen or other respiratory support.

2. DO NOT induce vomiting.

3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.

4. Activated charcoal is of no value.

5. Give the victims water or milk: children up to 1 year old, 125 mL (4 oz or 1/2 cup); children 1 to 12 years old, 200 mL (6 oz or 3/4 cup); adults, 250 mL (8 oz or 1 cup).
Water or milk should be given only if victims are conscious and alert.

6. Transport to a health care facility.

Fire Fighting of Ethylenediamine:
Wear full protective clothing including gloves and boots.
If necessary to enter closed area, wear full-faced gas masks with self-contained breathing apparatus.

Use water spray, dry chemical, alcohol foam, or carbon dioxide.
Do not use water in case of drum or tank fires.

If a leak or spill has not ignited, use water spray to reduce the vapors and dilute spills to nonflammable mixtures.
Use water to keep fire-exposed containers cool.

Fire Fighting Procedures:
Use water spray, dry chem, "alcohol resistant" foam, or carbon dioxide. Use water spray to keep fire-exposed containers cool.
Solid streams may be ineffective and spread material.

Identifiers of Ethylenediamine:
CAS Number: 107-15-3
Abbreviations: en
Beilstein Reference: 605263
ChEBI: CHEBI:30347
ChEMBL: ChEMBL816
ChemSpider: 13835550
ECHA InfoCard: 100.003.154
EC Number: 203-468-6
Gmelin Reference: 1098
KEGG: D01114
MeSH: ethylenediamine
PubChem CID: 3301
RTECS number: KH8575000
UNII: 60V9STC53F
UN number: 1604
CompTox Dashboard (EPA): DTXSID5021881
InChIInChI=1S/C2H8N2/c3-1-2-4/h1-4H2
Key: PIICEJLVQHRZGT-UHFFFAOYSA-N
SMILES: NCCN

Synonyms: 1,2-Diaminoethane
Linear Formula: NH2CH2CH2NH2
CAS Number: 107-15-3
Molecular Weight: 60.10
EC Number: 203-468-6

CAS number: 107-15-3
EC index number: 612-006-00-6
EC number: 203-468-6
Hill Formula: C₂H₈N₂
Chemical formula: H₂NCH₂CH₂NH₂
Molar Mass: 60.10 g/mol
HS Code: 2921 21 00

Properties of Ethylenediamine:
Chemical formula: C2H8N2
Molar mass: 60.100 g·mol−1
Appearance: Colorless liquid[3]
Odor: Ammoniacal[3]
Density: 0.90 g/cm3[3]
Melting point: 8 °C (46 °F; 281 K)[3]
Boiling point: 116 °C (241 °F; 389 K)[3]
Solubility in water: miscible
log P: −2.057
Vapor pressure: 1.3 kPa (at 20 °C)
Henry's law constant (kH): 5.8 mol Pa−1 kg−1
Magnetic susceptibility (χ):
-46.26·10−6 cm3/mol
-76.2·10−6 cm3/mol (HCl salt)
Refractive index (nD): 1.4565

Density: 0.897 g/cm3 (20 °C)
Explosion limit: 2 - 17 %(V)
Flash point: 38 °C
Ignition temperature: 405 °C
Melting Point: 11.1 °C
pH value: 12.2 (100 g/l, H₂O, 20 °C)
Vapor pressure: 12 hPa (20 °C)

Formula: C2H8N2
Formula mass: 60.10
Melting point, °C: 8.5
Boiling point, °C: 117
Vapor pressure, mmHg: 16 (25 C)
Vapor density (air=1): 2.07
Saturation Concentration: 1.3% at 20 C
Evaporization number: 0.91 (butyl acetate = 1)
Critical temperature: 340
Critical pressure: 66.19
Density: 0.898 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.54 cp (25 C)
Surface tension: 40.77 g/s2 (20 C)
Refractive index: 1.454 (20 C)
Dipole moment: 1.83 D (25 C)
Dielectric constant: 16 (18 C)
pKa/pKb: 4.11 (pKb)
Partition coefficient, pKow: -2.04
Heat of fusion: 19.3 kJ/mol
Heat of vaporization: 46.9 kJ/mol
Heat of combustion: -1890 kJ/mol

Molecular Weight: 60.10
XLogP3: -2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 60.068748264
Monoisotopic Mass: 60.068748264
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 4
Complexity: 6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Specifications of Ethylenediamine:
Color according to color reference solution Ph.Eur.: colorless liquid
Assay (GC, area%): ≥ 99.0 % (a/a)
Water (GC, area%): ≤ 1.0 % (a/a)
Density (d 20 °C/ 4 °C): 0.896 - 0.898
Identity (IR): passes test

Melting Point: >300.0°C
Color: White
pH: 3.9 to 5 (1% aq. soln.)
Assay Percent Range: 98+%
Infrared Spectrum: Authentic
Linear Formula: H2NCH2CH2NH2·2HCl
Beilstein: 04, 230
Packaging: Plastic bottle
Merck Index: 15, 3849
Quantity: 100 g
Solubility Information: (1% in water) Clear colorless
IUPAC Name: ethane-1,2-diamine;dihydrochloride
Formula Weight: 133.04
Percent Purity: 98+%
Physical Form: Crystalline Powder
Chemical Name or Material: Ethylenediamine dihydrochloride, 98+%

Thermochemistry of Ethylenediamine:
Heat capacity (C): 172.59 J K−1 mol−1
Std molar entropy (S⦵298): 202.42 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −63.55–−62.47 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −1.8678–−1.8668 MJ mol−1

Related compounds of Ethylenediamine:
Ethylamine
Ethylenedinitramine

Related alkanamines:
1,2-Diaminopropane
1,3-Diaminopropane

Names of Ethylenediamine:

Regulatory process names:
1,2-Diamino-ethaan
1,2-Diamino-ethano
1,2-Diaminoaethan
1,2-Diaminoethane
1,2-diaminoethane
1,2-Ethanediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Algicode 106L
Amerstat 274
beta-Aminoethylamine
Dimethylenediamine
Edamine
Ethyleendiamine
Ethylendiamine
Ethylenediamine
ETHYLENEDIAMINE
ethylenediamine
Ethylenediamine
EDA
ethylenediamine; 1,2-diaminoethane

Translated names:
1,2 diaminoetaani (fi)
1,2-Diamino-ethan (de)
1,2-diaminoetaan (et)
1,2-diaminoetan (hr)
1,2-diaminoetan (no)
1,2-diaminoetan (pl)
1,2-diaminoetan (ro)
1,2-diaminoetan (sl)
1,2-diaminoetan (sv)
1,2-diaminoetanas (lt)
1,2-diaminoetán (hu)
1,2-diaminoetāns (lv)
1,2-диаминоетан (bg)
etano-1,2-diamina (pl)
ethan-1,2-diamin (cs)
ethyleendiamine (nl)
ethylendiamin (cs)
ethylendiamin (da)
Ethylendiamin (de)
etilen-diamina (ro)
etilendiamin (hr)
etilendiamin (sl)
etilendiamina (es)
etilendiamina (it)
etilendiaminas (lt)
etilenodiamina (pt)
etilén-diamin (hu)
etilēndiamīns (lv)
etyleenidiamiini (fi)
etylendiamin (no)
etylendiamin (sv)
etylenodiamina (pl)
etyléndiamín (sk)
etán-1,2-diamín (sk)
Etüleendiamiin (et)
éthylènediamine;1,2-diaminoéthane (fr)
αιθυλενοδιαμίν (el)
етилендиамин (bg)

CAS name:
1,2-Ethanediamine

IUPAC names:
1,2,-Diaminoethane
1,2-Diaminoethane
1,2-diaminoethane
1,2-Diaminoethane , 1,2-Ethylenediamine , 1,4-Diazabutane , Dimethylenediamine
1,2-Ethanediamine
Diaminoethane
Ethane-1,2-diamine
ethane-1,2-diamine
ethane-1,2-diamine
Ethylendiamin
ethylene diamine
Ethylene diamine
ethylene diamine
Ethylenediamine
ethylenediamine
Ethylenediamine
ethylenediamine 1,2-diaminoethane
Ethylenediamine Anhydrous
ethylenediamine; 1,2-diaminoethane

Preferred IUPAC name:
Ethane-1,2-diamine

Trade names:
Bruggolen P22
EDA
Ethylenediamine
ETHYLENEDIAMINE (EDA)
ETHYLENEDIAMINE.
Ethylenediamine.

Other names:
Edamine,
1,2-Diaminoethane,
'en' when a ligand

Synonyms of Ethylenediamine:
ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethylenediamine [JAN]
NCI-C60402
Edamine [INN]
ETHYLENEDIAMINE ANHYDROUS
CHEBI:30347
CHEMBL816
H2NCH2CH2NH2
ETHANE,1,2-DIAMINO
60V9STC53F
27308-78-7
2-Aminoethylammonium chloride
1, 2-Diaminoethane
NCGC00091527-01
1,2-diaminoethane phase II
EN
1,2-diaminoethane phase I beta
Aethaldiamin [German]
Caswell No. 437
1,2-diaminoethane phase I alpha
Ethyleendiamine [Dutch]
Aethylenediamin [German]
Ethylene-diamine [French]
Ethane-1,2-diammonium bromide
CAS-107-15-3
Ethylenediamine, ReagentPlus(R), >=99%
1,2-Diaminoaethan [German]
1,2-Diamino-ethaan [Dutch]
CCRIS 5224
HSDB 535
1,2-Diamino-ethano [Italian]
Aminophylline Injection
EINECS 203-468-6
UN1604
EPA Pesticide Chemical Code 004205
Ethylenediamine [USP:JAN]
BRN 0605263
UNII-60V9STC53F
ethylenediarnine
AI3-24231
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
ethylene - diamine
EDN
1,2-ethylendiamine
MFCD00008204
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine [UN1604] [Corrosive]
.beta.-Aminoethylamine
ethane-1, 2-diamine
N,N'-ethylene diamine
Ethylenediamine, BioXtra
Epitope ID:117724
EC 203-468-6
ETHYLENEDIAMINE [II]
ETHYLENEDIAMINE [MI]
4-04-00-01166 (Beilstein Handbook Reference)
Ethylenediamine (USP/JP15)
Ethylenediamine (USP/JP17)
ETHYLENEDIAMINE [HSDB]
ETHYLENEDIAMINE [INCI]
BDBM7972
NH2(CH2)2NH2
ETHYLENEDIAMINE [MART.]
DTXSID5021881
ETHYLENEDIAMINE [WHO-DD]
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, analytical standard
STR00309
Tox21_111145
Tox21_201202
STL264241
ZINC37253587
ETHYLENEDIAMINE [EP MONOGRAPH]
AKOS000118850
DB14189
ETHYLENEDIAMINE [USP MONOGRAPH]
UN 1604
Ethylenediamine, for synthesis, 99.0%
NCGC00091527-02
NCGC00258754-01
BP-20367
Ethylenediamine [UN1604] [Corrosive]
E0077
E0081
EN300-19398
D01114
Ethylenediamine, SAJ special grade, >=99.0%
Ethylenediamine, meets USP testing specifications
Ethylenediamine, Vetec(TM) reagent grade, >=98%
Q411362
J-001723
Ethylenediamine, purified by redistillation, >=99.5%
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Z104473714
Ethylenediamine, puriss. p.a., absolute, >=99.5% (GC)
QuadraPure(R) AEA, 100-400 mum particle size, extent of labeling: 1.3 mmol/g loading, 1 % cross-linked with divinylbenzene
Ethylenediamine [JAN] [Wiki]
1,2-diamino ethane
1,2-DIAMINOETHANE
1,2-Ethandiamin [German] [ACD/IUPAC Name]
1,2-Ethanediamine [ACD/Index Name] [ACD/IUPAC Name]
1,2-Éthanediamine [French] [ACD/IUPAC Name]
1,2-ethylenediamine
107-15-3 [RN]
203-468-6 [EINECS]
605263 [Beilstein]
edamina [Spanish] [INN]
edamine [INN]
édamine [French] [INN]
edaminum (R) [Latin] [INN]
ethane-1,2-diamine
ethylene diamine
MFCD00008204 [MDL number]
эдамин [Russian] [INN]
乙二胺 [Chinese] [INN]
1,2-Diamino-ethaan [Dutch]
1,2-Diaminoethane, 1,2-Ethanediamine
1,2-Diamino-ethano [Italian]
1,4-DIAZABUTANE
2-aminoethynylamine
4-04-00-01166 [Beilstein]
8030-24-8 secondary RN [RN]
Aethaldiamin [German]
Aethylenediamin [German]
Amerstat 274
Diaminoethane
Dimethylenediamine
EDA (ethylenediamine)
EDN
EPI-DA (ethylenediamine)
ETHANE,1,2-DIAMINO
Ethyleendiamine [Dutch]
Ethylendiamine
Ethylene-d4 Diamine
Ethylene-diamine [French]
Ethylenediaminemissing
ethyne-1,2-diamine
β-Aminoethylamine
β-Aminoethylamine

Ethylenediamine appears as a clear colorless liquid with an ammonia-like odor.
Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine derives from a hydride of an ethane.


CAS Number: 107-15-3
EC Number: 203-468-6
Molecular Formula: C2H8N2 or H2NCH2CH2NH2 or NH2CH2CH2NH2


Ethylenediamine's Flash point is 91 °F and a melting point of 47 °F.
Ethylenediamine's Vapors are heavier than air.
Ethylenediamine's density is 7.5 lb / gal.


Ethylenediamine is an alkane-alpha,omega-diamine in which the alkane is ethane.
Ethylenediamine has a role as a GABA agonist.
Ethylenediamine derives from a hydride of an ethane.


Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Sensitivity to ethylenediamine may be identified with a clinical patch test.
Ethylenediamine (abbreviated as en when a ligand) is the organic compound with the formula C2H4(NH2)2.


This colorless liquid, Ethylenediamine, with an ammonia-like odor is a basic amine.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000 tonnes produced in 1998.
Ethylenediamine is the first member of the so-called polyethylene amines.


Ethylenediamine dihydrochloride is a glycol ether that has been used as a solvent and plasticizer.
Ethylenediamine has the ability to convert nitrite ions into nitrous acid, which is an important reaction in the formation of DNA.
Ethylenediamine has been studied for its potential use in transfection experiments and structural analysis.


Ethylenediamine is also an ingredient of aminophylline, a xanthine bronchodilator used in the treatment of asthma and other respiratory problems.
Other medications where Ethylenediamine or its derivatives are found include some antihistamines and anti-nausea agents.
Ethylenediamine is thick, colorless to light-yellowish liquid with an ammonia-like odor, hygroscopic, lachrymator.


Ethylenediamine is the organic compound with the formula C2H4(NH2)2.
This colorless liquid, Ethylenediamine, with an ammonia-like odor is a strongly basic amine.
Ethylenediamine is a widely used building block in chemical synthesis, with approximately 500,000,000 kg being produced in 1998.


Ethylenediamine is the ethyleneamine with the lowest molecular weight.
Ethylenediamine contains two primary amine groups and is a colorless liquid.
Ethylenediamine is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.



USES and APPLICATIONS of ETHYLENEDIAMINE:
Ethylenediamine is used in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.
Release to the environment of Ethylenediamine can occur from industrial use: of articles where the substances are not intended to be released and where the conditions of use do not promote release.


Ethylenediamine can be found in products with material based on: wood (e.g. floors, furniture, toys).
Ethylenediamine is used in the following products: adhesives and sealants, coating products, pH regulators and water treatment products, fillers, putties, plasters, modelling clay and water treatment chemicals.


Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment, health services and scientific research and development.
Ethylenediamine is used in the following products: fuels.


Other release to the environment of Ethylenediamine is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use resulting in inclusion into or onto a materials (e.g. binding agent in paints and coatings or adhesives), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediamine can occur from industrial use: formulation of mixtures.
Ethylenediamine is used in the following products: pH regulators and water treatment products, adhesives and sealants, coating products, heat transfer fluids, hydraulic fluids and polymers.


Ethylenediamine has an industrial use resulting in manufacture of another substance (use of intermediates).
Ethylenediamine is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment.
Ethylenediamine is used for the manufacture of: chemicals.


Release to the environment of Ethylenediamine can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates), for thermoplastic manufacture, in processing aids at industrial sites, of substances in closed systems with minimal release, in the production of articles and as processing aid.


Release to the environment of Ethylenediamine can occur from industrial use: manufacturing of the substance.
Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.


Because of its bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.
Ethylenediamine is used to make other chemicals and as a fungicide.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.


Notably, ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Ethylenediamine is an organic compound that is used as a building block for the production of many other chemical products.
Ethylenediamine is also used as an excipient in many pharmacological preparations such as creams.


Notably, Ethylenediamine is a contact sensitizer capable of producing local and generalized reactions.
Sensitivity to Ethylenediamine may be identified with a clinical patch test.
Ethylenediamine is approved for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.


Ethylenediamine is used mainly as a building block for crop protection products, in the synthesis of chelating agents and for low-temperature-active bleaching agents.
The many other applications of Ethylenediamine include polyamides, lubricants, fuel additives and textiles.
Ethylenediamine is used as a building block for the synthesis of bleach activators, chelates and crop protection products.


Furthermore Ethylenediamine is used as an intermediate in applications like corrosion inhibitors, polyamide resins and lubricants/fuel additives.
Chain extender in the production of poyurethane resin for the water PU Dispersion (PUD).
Products derived from Ethylenediamine are frequently used for bleach activators and chelates in detergents and for fungicides in crop protection area.


Ethylenediamine is used as a solvent, it is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.
Ethylenediamine is used as a corrosion inhibitor in paints and coolants.


Ethylenediamine is added to animal feeds as a source of iodide.
Ethylenediamine is used as chemicals for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxies, and dyes.
Ethylenediamine is used as a compound to sensitize nitromethane into an explosive.


This mixture was used at Picatinny Arsenal during WWII, giving the nitromethane and ethylenediamine mixture the nickname PLX, or Picatinny Liquid Explosive.
Ethylenediamine is commonly used as an intermediate to produce detergents, chelates, textile auxiliaries, agrochemicals and polyamides.
Uses of Ethylenediamine: Solvent for casein, albumin, shellac, and sulfur, emulsifier, stabilizing rubber latex, as inhibitor in antifreeze solutions, in textile lubricants, pharmaceutic aid (aminophylline injection stabilizer).


Ethylenediamine dihydrochloride can also be used to study phase transitions at different temperatures, as well as its electrochemical properties.
Ethylenediamine is used as a solvent, it is miscible with polar solvents and is used to solubilize proteins such as albumins and casein.
Ethylenediamine is also used in certain electroplating baths.


Ethylenediamine is used as a corrosion inhibitor in paints and coolants.
Ethylenediamine is added to animal feeds as a source of iodide.
Ethylenediamine is used as chemical for color photography developing, binders, adhesives, fabric softeners, curing agents for epoxys, and dyes.


Ethylenediamine is used in large quantities for production of many industrial chemicals.
Ethylenediamine forms derivatives with carboxylic acids (including fatty acids), nitriles, alcohols (at elevated temperatures), alkylating agents, carbon disulfide, and aldehydes and ketones.
Because of its bifunctional nature, having two amines, Ethylenediamine readily forms heterocycles such as imidazolidines.


-Pharmaceutical ingredient:
Ethylenediamine is an ingredient in the common bronchodilator drug aminophylline, where it serves to solubilize the active ingredient theophylline.
Ethylenediamine has also been used in dermatologic preparations, but has been removed from some because of causing contact dermatitis.
When used as a pharmaceutical excipient, after oral administration Ethylenediamine's bioavailability is about 0.34, due to a substantial first-pass effect.
Less than 20% is eliminated by renal excretion.
Ethylenediamine-derived antihistamines are the oldest of the five classes of first-generation antihistamines, beginning with piperoxan aka benodain, discovered in 1933 at the Pasteur Institute in France, and also including mepyramine, tripelennamine, and antazoline.
The other classes are derivatives of ethanolamine, alkylamine, piperazine, and others (primarily tricyclic and tetracyclic compounds related to phenothiazines, tricyclic antidepressants, as well as the cyproheptadine-phenindamine family)


-Role in polymers:
Ethylenediamine, because it contains two amine groups, is a widely used precursor to various polymers.
Condensates derived from formaldehyde are plasticizers.
Ethylenediamine is widely used in the production of polyurethane fibers.
The PAMAM class of dendrimers are derived from ethylenediamine.


-Uses of Ethylenediamine:
*Corrosion inhibitors
*Wet-strength resins
*Fabric softeners
*Epoxy curing agents
*Polyamide resins
*Fuel additives
*Lube oil additives
*Asphalt additives


-Uses of Ethylenediamine:
*Ore flotation
*Corrosion inhibitors
*Ore flotation
*Asphalt
*Additives
*Corrosion inhibitors
*Epoxy curing agents
*Hydrocarbon purification
*Lube oil & fuel additives
*Mineral processing aids
*Polyamide resins


-Uses of Ethylenediamine:
*Surfactants
*Textile additives-paper wet-strength resins
*Fabric softeners
*Surfactants
*Coatings
*Urethanes
*Fuel additives
*Chemical intermediates
*Epoxy curing agents
*Lube oils
*Wet strength resins


-Uses of Ethylenediamine:
*Bleach Activator
*Chelating Agents
*Epoxy Curing Agents
*Fungicides
*Industrial Surfactants
*Lube, Oil and Fuel Additives
*Phosphonates
*Plastic Lubricants
*Polyamide Resins
*Urethane Chemicals
*Other applications



BENEFITS OF ETHYLENEDIAMINE:
*Consistent and predictable reaction products
*Easily derivatized
*Low vapor pressure
*High viscosity
*Low environmental impact
*Suitable for harsh conditions
*Low sensitivity
*Versatile



MARKETS OF ETHYLENEDIAMINE:
*Aerospace, Marine and Automotive
*Agriculture
*Construction and Housing
*Consumer Electronics
*Household Detergents and Cleaners
*Human and Animal Health Care
*Food
*Industrial Cleaners and Preservants
*Mining
*Personal Care
*Pulp and Paper
*Road Construction
*Textiles and Sports



BENEFITS OF ETHYLENEDIAMINE:
*Consistent and predictable reaction products
*Easily derivatized
*Low vapor pressure
*High viscosity
*Low environmental impact
*Suitable for harsh conditions
*Low sensitivity
*Versatile



SYNTHESIS OF ETHYLENEDIAMINE:
Ethylenediamine is manufactured by reacting ammonia and 1,2-dichloroethane.
The reaction yields the mixture of ethylenediamine and the linear polyamines.
A simplified equation would be:
ClCH2CH2Cl + 4 NH3 → H2NCH2CH2NH2 + 2 NH4Cl



WHAT IS ETHYLENEDIAMINE AND WHERE IS ETHYLENEDIAMINE FOUND?
Ethylenediamine is a potent sensitiser used in topical medications, particularly antibiotic/steroid creams for its chemical stabilizing properties.
Ethylenediamine has been commonly found that individuals who show a positive patch test reaction to ethylenediamine have used, a popular broad-spectrum antifungal/steroid cream, or one of its generic preparations.
Ethylenediamine is not used in ointment preparations and is rarely found in cosmetics and toiletries.



SYNTHESIS OF ETHYLENEDIAMINE:
Ethylenediamine is produced industrially by treating 1,2-dichloroethane with ammonia under pressure at 180 °C in an aqueous medium.
In this reaction hydrogen chloride is generated, which forms a salt with the amine.
The amine is liberated by addition of sodium hydroxide and can then be recovered by rectification.
Diethylenetriamine (DETA) and triethylenetetramine (TETA) are formed as by-products.

Another industrial route to ethylenediamine involves the reaction of ethanolamine and ammonia.
This process involves passing the gaseous reactants over a bed of nickel heterogeneous catalysts.
Ethylenediamine can be produced in the lab by the reaction of ethylene glycol and urea.
Ethylenediamine can be purified by treatment with sodium hydroxide to remove water followed by distillation.



COORDINATION CHEMISTRY OF ETHYLENEDIAMINE:
Ethylenediamine is a well-known bidentate chelating ligand for coordination compounds, with the two nitrogen atoms donating their lone pairs of electrons when ethylenediamine acts as a ligand.

Ethylenediamine is often abbreviated "en" in inorganic chemistry.
The complex [Co(ethylenediamine)3]3+ is an archetypical chiral tris-chelate complex.
The salen ligands, some of which are used in catalysis, are derived from the condensation of salicylaldehydes and ethylenediamine.

-Related ligands:
Related derivatives of ethylenediamine include ethylenediaminetetraacetic acid (EDTA), tetramethylethylenediamine (TMEDA), and tetraethylethylenediamine (TEEDA).
Chiral analogs of ethylenediamine include 1,2-diaminopropane and trans-diaminocyclohexane.



PRECURSOR TO PHARMACEUTICALS AND AGRICHEMICALS:
Numerous bio-active compounds contain the N-CH2-CH2-N linkage, including aminophylline and some antihistamines. Salts of ethylenebisdithiocarbamate are commercially significant fungicides under the brandnames Maneb, Mancozeb, Zineb, and Metiram. Some imidazoline-containing fungicides are derived from ethylenediamine.



PRECURSOR TO CHELATING AGENTS:
The most prominent derivative of Ethylenediamine is EDTA, which is derived from ethylenediamine via a Strecker synthesis involving cyanide and formaldehyde. Hydroxyethylethyelenediamine is another commercially significant chelating agent.
The salen ligands, derived from the condensation of salicaldehydes and ethylenediamine, are popular chelating agents in the research laboratory although not commercially significant.



TETRAACETYLETHYLENEDIAMINE:
The bleaching activator tetraacetylethylenediamine is generated from ethylenediamine.
The derivative N,N-ethylenebis(stearamide) (EBS) is a commercially significant mold-release agent and a surfactant in gasoline and motor oil.



ROLE IN POLYMERS:
Ethylenediamine, by virtue of its bifunctionality (i.e. it contains two reactive amines) is widely used in diverse polyester formulations. Condensates derived from formaldehyde are plasticizers. It is widely used in the production of polyurethane fibers. The PAMAM class of dendrimers are derived from ethylenediamine.



ETHYLENEAMINES:
Ethylenediamine is the first member of the so-called polyethylene amines, other members being:
Diethylenetriamine, abbreviated dien or DETA, (H2N-CH2CH2-NH-CH2CH2-NH2, an analog of diethylene glycol)
Triethylenetetramine, abbreviated trien or TETA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2)

Tetraethylenepentamine, abbreviated TEPA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2),
Pentaethylenehexamine, abbreviated PEHA, (H2N-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH-CH2CH2-NH2), up to polyethylene amine. Similarly piperazine is an analogue of dioxane.

Related diamines:
In terms of quantities produced, ethylenediamine is the most significant diamine (aside from diaminohexane, which is a precursor to Nylon 66).
Related derivatives of ethylenediamine include tetramethylethylenediamine, abbreviated (TMEDA), (CH3)2N-CH2CH2-N(CH3)2 and tetraethylethylenediamine, abbreviated (TEEDA), (C2H5)2N-CH2CH2-N(C2H5)2



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINE:
Molecular Weight: 60.10
XLogP3: -2
Hydrogen Bond Donor Count: 2
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 1
Exact Mass: 60.068748264
Monoisotopic Mass: 60.068748264
Topological Polar Surface Area: 52 Ų
Heavy Atom Count: 4
Formal Charge: 0
Complexity: 6
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes

Flash point: 34 °C (93 °F; 307 K)
Autoignition temperature: 385 °C (725 °F; 658 K)
Explosive limits: 2.7–16%
Heat capacity (C): 172.59 J K−1 mol−1
Std molar entropy (S⦵298): 202.42 J K−1 mol−1
Std enthalpy of formation (ΔfH⦵298): −63.55–−62.47 kJ mol−1
Std enthalpy of combustion (ΔcH⦵298): −1.8678–−1.8668 MJ mol−1
Chemical formula: C2H8N2
Molar mass: 60.100 g·mol−1
Appearance: Colorless liquid
Odor: Ammoniacal
Density: 0.90 g/cm3
Melting point: 8 °C (46 °F; 281 K)
Boiling point: 116 °C (241 °F; 389 K)
Solubility in water: miscible
log P: −2.057
Vapor pressure: 1.3 kPa (at 20 °C)
Henry's law constant (kH): 5.8 mol Pa−1 kg−1
Magnetic susceptibility (χ): -46.26·10−6 cm3/mol
-76.2·10−6 cm3/mol (HCl salt)
Refractive index (nD): 1.4565

Formula: C2H8N2
Formula mass: 60.10
Melting point, °C: 8.5
Boiling point, °C: 117
Vapor pressure, mmHg: 16 (25 C)
Vapor density (air=1): 2.07
Saturation Concentration: 1.3% at 20 C
Evaporization number: 0.91 (butyl acetate = 1)
Critical temperature: 340
Critical pressure: 66.19
Density: 0.898 g/cm3 (20 C)
Solubility in water: Miscible
Viscosity: 1.54 cp (25 C)
Surface tension: 40.77 g/s2 (20 C)
Refractive index: 1.454 (20 C)
Dipole moment: 1.83 D (25 C)
Dielectric constant: 16 (18 C)

pKa/pKb: 4.11 (pKb)
Partition coefficient, pKow: -2.04
Heat of fusion: 19.3 kJ/mol
Heat of vaporization: 46.9 kJ/mol
Heat of combustion: -1890 kJ/mol
Physical state: liquid
Color: colorless
Odor: amine-like
Melting point/freezing point
Melting point/range: 8,5 °C
Initial boiling point and boiling range: 118 °C
Flammability (solid, gas): No data available
Upper/lower flammability or explosive limits:
Upper explosion limit: 17 %(V)
Lower explosion limit: 2 %(V)
Flash point: 38 °C - closed cup

Autoignition temperature: 405 °C
Decomposition temperature: > 120 °C
pH: 12,2 at 100 g/l at 20 °C
Viscosity
Viscosity, kinematic: No data available
Viscosity, dynamic: 1,265 - 1,725 mPa.s at 25 °C
Water solubility 1.000 g/l - miscible
Partition coefficient: n-octanol/water:
log Pow: -2,04 - Bioaccumulation is not expected., (Lit.)
Vapor pressure 12 hPa at 20 °C
Density 0,899 g/mL at 25 °C
Relative density No data available
Relative vapor density: No data available
Particle characteristics: No data available
Explosive properties: No data available
Oxidizing properties: none

Other safety information:
Relative vapor density: 2,07 - (Air = 1.0)
CAS number: 107-15-3
EC index number: 612-006-00-6
EC number: 203-468-6
Hill Formula: C₂H₈N₂
Chemical formula: H₂NCH₂CH₂NH₂
Molar Mass: 60.10 g/mol
HS Code: 2921 21 00
Density: 0.897 g/cm3 (20 °C)
Explosion limit: 2 - 17 %(V)
Flash point: 38 °C
Ignition temperature: 405 °C
Melting Point: 11.1 °C
pH value: 12.2 (100 g/l, H₂O, 20 °C)
Vapor pressure: 12 hPa (20 °C)

Physical description: Colorless, viscous liquid with an ammonia-like odor.
Boiling point: 241°F
Molecular weight: 60.1
Freezing point/melting point: 47°F
Vapor pressure: 11 mmHg
Flash point: 93°F
Vapor density: 2.07
Specific gravity: 0.91
Ionization potential: 8.60 eV
Lower explosive limit (LEL): 4.2%
Upper explosive limit (UEL): 14.4%
NFPA health rating: 3
NFPA fire rating: 2
NFPA reactivity rating: 0
NFPA special instruction: 0



FIRST AID MEASURES of ETHYLENEDIAMINE:
-Description of first-aid measures:
*General advice:
First aiders need to protect themselves.
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
Immediately call in physician.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
Call a physician immediately.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Immediately call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Make victim drink water (two glasses at most), avoid vomiting.
Call a physician immediately.
Do not attempt to neutralise.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINE:
-Personal precautions, protective equipment and emergency procedures:
*Advice for non-emergency personnel:
Ensure adequate ventilation.
Evacuate the danger area, observe emergency procedures, consult an expert.
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up carefully with liquid-absorbent material.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINE:
-Extinguishing media:
*Suitable extinguishing media:
Water
Foam
Carbon dioxide (CO2)
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Remove container from danger zone and cool with water.
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINE:
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Tightly fitting safety goggles
*Skin protection:
Full contact:
Material: butyl-rubber
Minimum layer thickness: 0,7 mm
Break through time: 480 min
Splash contact:
Material: Chloroprene
Minimum layer thickness: 0,65 mm
Break through time: 240 min
*Body Protection:
Flame retardant antistatic protective clothing.
*Respiratory protection:
Recommended Filter type: Filter A
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENEDIAMINE:
-Precautions for safe handling:
*Hygiene measures:
Immediately change contaminated clothing.
Apply preventive skin protection.
Wash hands and face after working with substance.
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Keep container tightly closed in a dry and well-ventilated place.
Keep locked up or in an area accessible only to qualified or authorized persons.
Handle and store under inert gas.



STABILITY and REACTIVITY of ETHYLENEDIAMINE:
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
Absorbs carbon dioxide (CO2) from air.
-Possibility of hazardous reactions:
No data available



SYNONYMS:
ethylenediamine
Ethane-1,2-diamine
107-15-3
1,2-Ethanediamine
1,2-Diaminoethane
Ethylene diamine
Ethylendiamine
edamine
Dimethylenediamine
1,2-Ethylenediamine
Aethaldiamin
Aethylenediamin
Ethyleendiamine
Ethylene-diamine
beta-Aminoethylamine
1,2-Diaminoaethan
Algicode 106L
Amerstat 274
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethylenediamine [JAN]
NCI-C60402
Edamine [INN]
ETHYLENEDIAMINE ANHYDROUS
CHEBI:30347
CHEMBL816
H2NCH2CH2NH2
ETHANE,1,2-DIAMINO
60V9STC53F
27308-78-7
DTXSID5021881
2-Aminoethylammonium chloride
1, 2-Diaminoethane
NCGC00091527-01
1,2-diaminoethane phase II
EN
DTXCID501881
1,2-diaminoethane phase I beta
Aethaldiamin [German]
Caswell No. 437
1,2-diaminoethane phase I alpha
Ethane-1,2-diammonium bromide
CAS-107-15-3
Ethylenediamine, ReagentPlus(R), >=99%
CCRIS 5224
HSDB 535
Aminophylline Injection
EINECS 203-468-6
UN1604
EPA Pesticide Chemical Code 004205
Ethylenediamine [USP:JAN]
BRN 0605263
UNII-60V9STC53F
ethylenediarnine
AI3-24231
2-aminoethylamine
ethylene di amine
1,4-diazabutane
1,2-diaminoethan
ethylene - diamine
EDN
1,2-ethylendiamine
MFCD00008204
1,2-diamino-ethane
ethane 1,2-diamine
N,N'-ethylenediamine
Ethylenediamine, 8CI
1,2-ethylene diamine
1,2-ethylene-diamine
Ethylenediamine [UN1604]
.beta.-Aminoethylamine
ethane-1, 2-diamine
N,N'-ethylene diamine
Ethylenediamine, BioXtra
Epitope ID:117724
EC 203-468-6
ETHYLENEDIAMINE [II]
ETHYLENEDIAMINE [MI]
4-04-00-01166 (Beilstein Handbook Reference)
Ethylenediamine (USP/JP15)
Ethylenediamine (USP/JP17)
ETHYLENEDIAMINE [HSDB]
ETHYLENEDIAMINE [INCI]
BDBM7972
NH2(CH2)2NH2
ETHYLENEDIAMINE [MART.]
ETHYLENEDIAMINE [WHO-DD]
624-59-9 (di-hydrobromide)
333-18-6 (di-hydrochloride)
5700-49-2 (di-hydriodide)
Ethylenediamine, analytical standard
STR00309
Tox21_111145
Tox21_201202
STL264241
ZINC37253587
ETHYLENEDIAMINE [EP MONOGRAPH]
AKOS000118850
DB14189
ETHYLENEDIAMINE [USP MONOGRAPH]
UN 1604
Ethylenediamine, for synthesis, 99.0%
NCGC00091527-02
NCGC00258754-01
BP-20367
Ethylenediamine [UN1604]
E0077
E0081
EN300-19398
D01114
Ethylenediamine, SAJ special grade, >=99.0%
Ethylenediamine, meets USP testing specifications
Ethylenediamine, Vetec(TM) reagent grade, >=98%
Q411362
J-001723
Ethylenediamine, purified by redistillation, >=99.5%
TIZANIDINE HYDROCHLORIDE IMPURITY H [EP IMPURITY]
Z104473714
Ethylenediamine, puriss. p.a., absolute, >=99.5% (GC)
1.3 mmol/g loading, 1 % cross-linked with divinylbenzene
Ethane-1,2-diamine
Edamine
1,2-Diaminoethane
1,2-Diaminoethane
1,2-Ethanediamine
Ethylenediamine (anhydrous)
1,2-Ethanediamine
β-Aminoethylamine
Dimethylenediamine
Ethane-1,2-diamine
1,2-Diaminoethane
1,2-Ethylenediamine
H2NCH2CH2NH2
Aethaldiamin
Aethylenediamin
1,2-Diaminoaethan
1,2-Diamino-ethaan
1,2-Diamino-ethano
Ethyleendiamine
Ethylendiamine
NCI-C60402
UN 1604

Ethylenediamine (EDA), also known as 1,2-diaminoethane, is an organic compound with the chemical formula C2H8N2.
Ethylenediamine (EDA) is a colorless liquid with an ammonia-like odor.
Ethylenediamine (EDA) is a simple diamine, meaning it contains two amino groups (-NH2) separated by two carbon atoms.

CAS Number: 107-15-3
EC Number: 203-468-6

Ethylenediamine, EDA, 1,2-diaminoethane, 1,2-ethanediamine, 1,2-Diaminoethane, Ethane-1,2-diamine, 1,2-Ethylenediamine, Aethaldiamine, 1,2-Diazaethane, Ethylamine, Diaminoethane, Ethylenediamin, Glycolamine, Ethane-1,2-diyldiamine, α,ω-Diaminoethane, H2NCH2CH2NH2, Dimethylethylenediamine, 1,2-Diaminethylethane, Ethyleneimine, N,N'-Bis(2-aminoethyl)ethane-1,2-diamine, Ethylene Diamine, H2N(CH2)2NH2, Ethylamine, Diaminoethylene, 1,2-Ethandiamine, 1,2-エチレンジアミン, Diaminethylethane



APPLICATIONS


Ethylenediamine (EDA) is commonly used as a chelating agent in the formulation of metal ion complexes for various industrial processes.
Ethylenediamine (EDA) is utilized in the production of chelating agents such as EDTA (ethylenediaminetetraacetic acid) and DTPA (diethylenetriaminepentaacetic acid).
Ethylenediamine (EDA) is employed in the purification of water by complexing with metal ions and removing them from solution.

Ethylenediamine (EDA) serves as a precursor for the synthesis of polyamines, which are used as curing agents in epoxy resins and polyurethane foams.
Ethylenediamine (EDA) is an essential component in the manufacture of fungicides, herbicides, and insecticides for agricultural applications.

Ethylenediamine (EDA) is used in the production of pharmaceuticals, including antihistamines, antifungal agents, and local anesthetics.
Ethylenediamine (EDA) is employed as a catalyst in the synthesis of specialty chemicals and pharmaceutical intermediates.

Ethylenediamine (EDA) serves as a raw material in the synthesis of polymers such as nylon, polyamides, and polyurethanes.
Ethylenediamine (EDA) is utilized in the preparation of adhesives, coatings, and sealants for various industrial applications.
Ethylenediamine (EDA) acts as a solvent in the extraction of natural products and in the formulation of specialty chemicals.

Ethylenediamine (EDA) is used in the textile industry for dyeing and printing processes due to its ability to form stable complexes with metal ions.
Ethylenediamine (EDA) serves as a corrosion inhibitor in metalworking fluids, protecting metal surfaces from oxidation and rust.

Ethylenediamine (EDA) is employed in the synthesis of surfactants and detergents for use in cleaning and personal care products.
Ethylenediamine (EDA) serves as a complexing agent in the formulation of metal plating baths for electroplating processes.
Ethylenediamine (EDA) is utilized in the production of fuel additives, lubricants, and hydraulic fluids to improve performance and stability.

Ethylenediamine (EDA) acts as a pH regulator and stabilizer in industrial processes such as paper manufacturing and wastewater treatment.
Ethylenediamine (EDA) is used in the synthesis of ion exchange resins for water softening and purification applications.

Ethylenediamine (EDA) serves as a reagent in analytical chemistry for the determination of metal ions and complexometric titrations.
Ethylenediamine (EDA) is employed in the synthesis of specialty chemicals used in the electronics industry for semiconductor manufacturing.
Ethylenediamine (EDA) serves as a catalyst in the production of polyurethane elastomers and foams for automotive and construction applications.

Ethylenediamine (EDA) is utilized in the production of rubber chemicals, antioxidants, and vulcanization accelerators.
Ethylenediamine (EDA) serves as a stabilizer and antioxidant in the formulation of polymers and plastics to prevent degradation during processing and storage.

Ethylenediamine (EDA) is used in the synthesis of adhesives and sealants for bonding substrates in construction and automotive applications.
Ethylenediamine (EDA) serves as a reagent in the production of dyes, pigments, and photographic chemicals for printing and imaging applications.
Ethylenediamine (EDA) is an important chemical intermediate with diverse applications in various industries, contributing to the development of innovative materials and products.

Ethylenediamine (EDA) is used in the synthesis of ion-exchange resins for chromatography and purification applications in analytical chemistry.
Ethylenediamine (EDA) serves as a complexing agent in the formulation of metal complexes used as catalysts in organic synthesis.
Ethylenediamine (EDA) is employed in the preparation of metal nanoparticles and nanocomposites for catalysis and material science applications.

Ethylenediamine (EDA) is used in the production of specialty chemicals such as corrosion inhibitors, antifoaming agents, and scale inhibitors for industrial processes.
Ethylenediamine (EDA) is utilized in the formulation of adhesives and sealants for bonding substrates in aerospace and marine applications.

Ethylenediamine (EDA) serves as a component in the synthesis of crosslinking agents for the modification of polymers and elastomers.
Ethylenediamine (EDA) is employed in the synthesis of specialty resins for coatings, inks, and varnishes for architectural and industrial applications.

Ethylenediamine (EDA) serves as a chemical intermediate in the production of flavors, fragrances, and pharmaceutical excipients.
Ethylenediamine (EDA) is used in the formulation of metalworking fluids for lubrication and cooling during machining processes.
Ethylenediamine (EDA) serves as a reagent in the production of specialty gases, including ethylenediamine dinitrate (EDDN) for explosives and propellants.

Ethylenediamine (EDA) is employed in the synthesis of cationic surfactants and softeners for use in fabric softeners and textile finishing agents.
Ethylenediamine (EDA) serves as a crosslinking agent in the production of rubber vulcanizates for tire manufacturing and automotive applications.
Ethylenediamine (EDA) is used in the formulation of antifreeze and coolant additives for automotive and industrial cooling systems.

Ethylenediamine (EDA) serves as a stabilizer and dispersant in the formulation of emulsions and suspensions for pharmaceutical and cosmetic applications.
Ethylenediamine (EDA) is employed in the production of specialty polymers such as polyamide-imides and polyethyleneimines for high-performance applications.
Ethylenediamine (EDA) serves as a reagent in the synthesis of urea-formaldehyde resins for use in wood adhesives and composite materials.

Ethylenediamine (EDA) is utilized in the formulation of cleaning agents and degreasers for industrial and household applications.
Ethylenediamine (EDA) serves as a catalyst in the production of polyols and isocyanates for the synthesis of polyurethane foams and coatings.

Ethylenediamine (EDA) is employed in the synthesis of pharmaceutical intermediates such as benzylpenicillin and ethylenediaminetetraacetonitrile.
Ethylenediamine (EDA) serves as a crosslinking agent in the production of dental materials such as impression compounds and denture adhesives.

Ethylenediamine (EDA) is used in the formulation of inkjet inks and toners for printing and imaging applications.
Ethylenediamine (EDA) serves as a reagent in the synthesis of specialty polymers such as polycarboxylates for water treatment and concrete additives.

Ethylenediamine (EDA) is employed in the formulation of deicing agents and antifreeze solutions for aircraft and runway maintenance.
Ethylenediamine (EDA) serves as a component in the synthesis of pharmaceutical active ingredients such as antiviral drugs and anticancer agents.
Ethylenediamine (EDA) is an essential chemical with diverse applications across various industries, contributing to the development of advanced materials, technologies, and products.



DESCRIPTION


Ethylenediamine (EDA), also known as 1,2-diaminoethane, is an organic compound with the chemical formula C2H8N2.
Ethylenediamine (EDA) is a colorless liquid with an ammonia-like odor.
Ethylenediamine (EDA) is a simple diamine, meaning it contains two amino groups (-NH2) separated by two carbon atoms.

Ethylenediamine (EDA) is primarily used as a building block in the production of various chemicals, including chelating agents, polyurethane resins, fuel additives, and pharmaceuticals.
Ethylenediamine (EDA) is a versatile compound with strong nucleophilic properties, making it useful in many chemical reactions.

Ethylenediamine (EDA) is a colorless, viscous liquid at room temperature.
Ethylenediamine (EDA) has a distinctive ammonia-like odor, which is characteristic of primary amines.

Ethylenediamine (EDA) is highly soluble in water, alcohol, and other polar solvents.
Ethylenediamine (EDA) is hygroscopic, meaning it readily absorbs moisture from the air.

Ethylenediamine has a boiling point of approximately 116°C and a melting point of about −8°C.
Ethylenediamine (EDA) is miscible with many organic solvents, making it useful in various chemical reactions.

Ethylenediamine (EDA) is commonly used as a chelating agent to bind metal ions in solution.
Ethylenediamine (EDA) forms stable complexes with transition metals such as copper, iron, and nickel.

Ethylenediamine (EDA) is a versatile building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals.
Ethylenediamine (EDA) serves as a precursor for the synthesis of polyamines and polyamides.
Ethylenediamine (EDA) can act as a ligand in coordination chemistry, forming coordination complexes with metal ions.

Ethylenediamine (EDA) is used in the production of polyurethane foams, resins, and coatings.
Ethylenediamine (EDA) is employed as a curing agent for epoxy resins, enhancing their mechanical properties.
In the petroleum industry, EDA is used as a selective solvent for the removal of hydrogen sulfide and carbon dioxide from natural gas streams.

Ethylenediamine (EDA) is also utilized in the purification of hydrocarbon streams and as a corrosion inhibitor.
Ethylenediamine (EDA) is employed as a stabilizer and pH adjuster in industrial processes such as metal plating and textile manufacturing.
Ethylenediamine (EDA) serves as a precursor for the synthesis of ethylenediaminetetraacetic acid (EDTA), a widely used chelating agent in analytical chemistry.

Ethylenediamine (EDA) is an important component in the production of herbicides, fungicides, and insecticides.
Ethylenediamine (EDA) exhibits strong nucleophilic properties, facilitating reactions such as alkylation, acylation, and reductive amination.
Ethylenediamine (EDA) is used in the preparation of specialty chemicals, surfactants, and detergents.

Ethylenediamine (EDA) plays a role in the synthesis of dyes, pigments, and photographic chemicals.
Ethylenediamine can react with acids to form ethylenediammonium salts, which are used as ion-exchange resins and in the production of fertilizers.

In the pharmaceutical industry, EDA is employed in the synthesis of antihistamines, local anesthetics, and antifungal agents.
Due to its alkaline nature, ethylenediamine can cause skin and eye irritation upon contact and should be handled with caution.
Ethylenediamine (EDA) is a versatile compound with diverse applications in various industries, from chemical manufacturing to pharmaceuticals and beyond.



PROPERTIES


Physical Properties:

Appearance: Clear, colorless liquid
Odor: Ammonia-like odor
Density: 0.899 g/cm³ (at 20°C)
Melting Point: −8.5°C
Boiling Point: 116.8°C
Flash Point: 36°C (closed cup)
Vapor Pressure: 7.4 mmHg (at 20°C)
Solubility in Water: Completely miscible
Vapor Density: 2.6 (air = 1)
Refractive Index: 1.455 (at 20°C)


Chemical Properties:

Chemical Formula: C2H8N2
Molecular Weight: 60.10 g/mol
Structure: Ethylenediamine consists of two amino groups (-NH2) separated by two carbon atoms (-CH2-CH2-).
Solubility: Soluble in water, alcohol, and polar solvents
pH: Basic (alkaline) in aqueous solution
Acidity/Basicity: Exhibits basic properties due to the presence of amino groups
Reactivity: Ethylenediamine is a strong nucleophile and can undergo reactions such as alkylation, acylation, and complex formation with metal ions.
Stability: Generally stable under normal conditions, but may degrade upon exposure to heat, light, or air.
Flammability: Flammable liquid, forms flammable vapor-air mixtures.
Corrosivity: Can cause corrosion to metals upon prolonged contact.
Toxicity: Ethylenediamine is toxic if ingested and can cause skin and eye irritation upon contact.
Biodegradability: Biodegradable under aerobic conditions, but persistence in the environment may vary.
Hazardous Polymerization: Does not occur under normal conditions.
Autoignition Temperature: 390°C
Explosive Limits: Lower Explosive Limit (LEL) - 3.3% (Volume), Upper Explosive Limit (UEL) - 15.7% (Volume)



FIRST AID


Inhalation:

If Ethylenediamine vapors are inhaled and respiratory irritation occurs, immediately move the affected person to fresh air.
Allow the individual to rest in a well-ventilated area and provide them with oxygen if breathing difficulties persist.
If the person is not breathing or shows signs of respiratory distress, administer artificial respiration. Seek medical attention promptly.
Keep the person warm and comfortable. Do not leave them unattended.


Skin Contact:

In case of skin contact with Ethylenediamine, immediately remove contaminated clothing and shoes.
Rinse the affected area with plenty of water for at least 15 minutes to remove any residual chemical.
Wash the skin thoroughly with mild soap and water to remove any remaining traces of Ethylenediamine.
If skin irritation, redness, or rash develops, seek medical advice promptly.
Do not apply ointments or creams to the affected area unless instructed by medical personnel.


Eye Contact:

If Ethylenediamine comes into contact with the eyes, immediately flush the eyes with gently flowing water for at least 15 minutes.
Hold the eyelids open to ensure thorough rinsing and remove any contact lenses if present and easily removable.
Seek immediate medical attention, even if the affected person does not experience immediate symptoms.
Do not rub the eyes, as this may exacerbate irritation and cause further damage.


Ingestion:

If Ethylenediamine is ingested accidentally and the person is conscious, rinse their mouth thoroughly with water and encourage them to drink water or milk to dilute the chemical.
Do not induce vomiting unless instructed to do so by medical personnel, especially if the individual is unconscious or experiencing convulsions.
Seek medical advice immediately, and provide the healthcare provider with information about the ingested substance, including its name, concentration, and the amount ingested.
Monitor the person for signs of gastrointestinal distress, such as nausea, vomiting, or abdominal pain, and seek medical attention promptly if symptoms worsen or persist.


General Precautions:

Always handle Ethylenediamine with care and wear appropriate personal protective equipment (PPE) such as gloves, goggles, and protective clothing to prevent skin and eye contact.
Avoid breathing in vapors or mists of Ethylenediamine. Use local exhaust ventilation or respiratory protection if necessary.
Keep containers tightly closed when not in use and store them in a cool, dry, well-ventilated area away from sources of heat, ignition, and incompatible substances.
In case of a spill, contain the area and prevent further release of the chemical into the environment. Clean up spills promptly using appropriate absorbent materials and dispose of waste according to local regulations.



HANDLING AND STORAGE


Handling:

When handling Ethylenediamine (EDA), wear appropriate personal protective equipment (PPE) including chemical-resistant gloves, safety goggles, and protective clothing to prevent skin and eye contact.
Avoid breathing in vapors or mists of Ethylenediamine.
Use local exhaust ventilation or respiratory protection if necessary to control airborne exposure.
Ensure adequate ventilation in the work area to minimize the buildup of vapors or fumes. Use explosion-proof equipment in areas where flammable vapors may be present.
Prevent contact with incompatible materials such as strong acids, oxidizing agents, and alkalis, as they may react violently with Ethylenediamine and release hazardous gases.
Use caution when transferring or pouring Ethylenediamine to prevent spills and splashes. Use appropriate tools and equipment such as funnels or pumps to minimize contact with the chemical.
Keep containers tightly closed when not in use to prevent contamination and minimize exposure to air and moisture.
Avoid contact with skin, eyes, and clothing.
In case of contact, follow appropriate first aid measures and rinse thoroughly with water.
Do not eat, drink, or smoke while handling Ethylenediamine, and wash hands thoroughly after handling to prevent accidental ingestion.
Avoid prolonged or repeated exposure to Ethylenediamine, as it may cause skin irritation, sensitization, or allergic reactions in some individuals.
Handle Ethylenediamine with care to prevent spills, leaks, and releases into the environment.
Clean up spills promptly using appropriate absorbent materials and dispose of waste according to local regulations.


Storage:

Store Ethylenediamine in a cool, dry, well-ventilated area away from sources of heat, ignition, and direct sunlight.
Keep containers tightly closed and upright to prevent leakage or spills. Store larger quantities in suitable containers with secondary containment to contain spills.
Store Ethylenediamine away from incompatible materials such as strong acids, oxidizing agents, and alkalis to prevent reactions or contamination.
Ensure storage areas are equipped with appropriate firefighting equipment and spill containment materials in case of emergencies.
Follow local regulations and guidelines for the storage of chemicals, including any specific requirements for the storage of Ethylenediamine.
Keep storage areas clean and free from clutter to minimize the risk of spills and accidents.
Check containers regularly for signs of damage or deterioration and replace any damaged or compromised containers promptly.
Store Ethylenediamine in its original packaging or labeled containers to ensure proper identification and traceability.
Separate Ethylenediamine from incompatible materials by storing them in separate areas or using barriers to prevent contact.
Monitor storage conditions regularly to ensure compliance with safety guidelines and to prevent the buildup of hazardous conditions.

EDTA, DISODIUM; EDTA, Disodium Salt Dihydrate; Ethylenediaminetetraacetic acid disodium salt dihydrate; Ethanediylbis(N-(carboxymethyl)glycine) disodium salt; Disodium dihydrogen ethylenediaminetetraacetate; Versene disodium salt;cas no: 139-33-3

Ethylenediaminetetraacetic Acid (EDTA) is a colorless crystalline solid.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.


CAS Number: 60-00-4 (free acid)
6381-92-6 (dihydrate disodium salt)
EC Number: 200-449-4
MDL number: MFCD00003541
Linear Formula: (HO2CCH2)2NCH2CH2N(CH2CO2H)2
Molecular Formula : C10H16N2O8



SYNONYMS:
(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid, Edathamil, (Ethylenedinitrilo)tetraacetic acid, Ethylenedinitrilotetraacetic acid, EDTA, EDTA, Edetic acid, Ethylenediaminetetraacetic acid, 60-00-4, Edathamil, Sequestrol, Versene, Havidote, Titriplex, EDTA acid, Versene acid, Endrate, Cheelox, Gluma cleanser, Sequestrene aa, Sequestric acid, Warkeelate acid, Komplexon ii, Tetrine acid, Quastal Special, Metaquest A, Trilon bw, Titriplex II, Hamp-ene acid, Cheelox BF acid, Trilon BS, Celon A, Celon ATH, Chelest 3A, Questex 4H, (Ethylenedinitrilo)tetraacetic acid, Chemcolox 340, Universne acid, EDTA (chelating agent), Dissolvine E, Vinkeil 100, Nullapon B acid, Nullapon bf acid, Nervanaid B acid, Perma kleer 50 acid, Clewat TAA, Ethylenedinitrilotetraacetic acid, Acide edetique, Acido edetico, Acidum edeticum, Caswell No. 438, Versenate, ICRF 185, Calcium disodium versenate, Ethylenebisiminodiacetic acid, Ethylenediamine-N,N,N',N'-tetraacetic acid, SEQ 100, YD 30, Disodium EDTA, CCRIS 946, Chelaton 3, Ethylenebis(iminodiacetic acid), HSDB 809, Acide ethylenediaminetetracetique, ETHYLENEDIAMINE TETRAACETIC ACID, Cheladrate, Edetate calcium, Edetate disodium, Acide edetique [INN-French], Acido edetico [INN-Spanish], Acidum edeticum [INN-Latin], Acetic acid, (ethylenedinitrilo)tetra-, EPA Pesticide Chemical Code 039101, Ethylenediaminetetraacetate, Kyselina ethylendiamintetraoctova, Tricon bw, Acid, Edetic, AI3-17181, H4edta, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, 470462-56-7, EINECS 200-449-4, UNII-9G34HU7RV0, Edetate, BRN 1716295, Edta disodium, Versene-13C4, 9G34HU7RV0, Disodium edetate, Disodium versene, Endrate disodium, Sodium versenate, Edetic acid disodium salt, Kyselina ethylendiamintetraoctova [Czech], Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, Acide ethylenediaminetetracetique [French], Disodium edetate dihydrate, DTXSID6022977, Metaquest B, N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine), CHEBI:42191, ethylene diamine tetraacetic acid, Kiresuto B, Chelaplex III, Diso-Tate, Titriplex III, 2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid, Chelaton III, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), Versene NA, Triplex III, Disodium versenate, Edathamil disodium, Trilon BD, Versene Na2, Disodium sequestrene, Disodium tetracemate, EDTA disodium salt, MFCD00003541, EDTA, ion(4-), CHEMBL858, Sequestrene sodium 2, 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid, {[-(BIS-CARBOXYMETHYL-AMINO)-ETHYL]-CARBOXYMETHYL-AMINO}-ACETIC ACID, Disodium salt of EDTA, ethylenediamine tetracetic acid, DTXCID902977, Perma Kleer Di Crystals, (ethylenedinitrilo)tetraacetic acid, ion(4-), Calcium disodium versenate (TN), ethylene-diamine tetraacetic acid, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid, EC 200-449-4, 4-04-00-02449 (Beilstein Handbook Reference), EDT, Ethylenediaminetetraacetic acid disodium salt, Edetate calcium disodium (USP), Sequestrene Na2, Trilon B, Selekton B2, Disodium ethylenediaminetetraacetate, (ethane-1,2-diyldinitrilo)tetraacetic acid, EDETIC ACID (II), EDETIC ACID [II], Perma kleer 50 crystals disodium salt, Disodium (ethylenedinitrilo)tetraacetate, Disodium ethylenediaminetetraacetic acid, EDETIC ACID (MART.), EDETIC ACID [MART.], CaEDTA, N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycine], CBC 50152966, DR-16133, Ethylenediaminetetraacetate, disodium salt, EDETIC ACID (USP-RS), EDETIC ACID [USP-RS], ANTICOAGULANT ETHYLENEDIAMINE TETRAACETIC ACID, Disodium diacid ethylenediaminetetraacetate, D'E.d.t.a. disodique, Disodium (ethylenedinitrilo)tetraacetic acid, 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate, Disodium dihydrogen ethylenediaminetetraacetate, Ethylenediaminetetraacetic acid, disodium salt, ANTICOAGULANT ETHYLENEDIAMINE TETRAACETIC ACID (EDTA), Disodium ethylenediamine-N,N,N',N'-tetraacetate, EDETIC ACID (EP MONOGRAPH), EDETIC ACID [EP MONOGRAPH], Disodium dihydrogen(ethylenedinitrilo)tetraacetate, 139-33-3, C10H16N2O8, NSC2760, NCGC00159485-02, 6381-92-6, disodium-edta, Edetic, Edetic acid [INN:BAN:NF], ((-(bis-carboxymethyl-amino)-ethyl)-carboxymethyl-amino)-acetic acid, (Ethylenedinitrilo)tetraacetic acid, disodium salt, Versenic Acid, Acid, Ethylenediaminetetraacetic, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid, 2-(2-[bis(carboxymethyl)amino]ethylamino)acetic acid, Calcium Disodium Edetate (JAN), ethylenediamine tetra-acetic acid, Techrun DO, Acid, Ethylenedinitrilotetraacetic, EDTA, anhydrous, Zonon AO, EDTA, free acid, EDTA, free base, ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT, Versene acid (TN), ethylenediaminetetraacetic acid (edta), Caswell No 438, Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl))-, Ethylenediamine-tetraacetic acid (EDTA), Acroma DH 700, Spectrum_001018, Edetic acid (NF/INN), EDTA [VANDF], Spectrum2_000003, Spectrum3_000412, Spectrum4_000531, Spectrum5_000955, EDTA [INCI], Edetic acid [BAN:INN], EDETIC ACID [INN], EDTA [MI], EDETIC ACID [HSDB], EDTA, anhydrous ACS grade, ethylenediaminetetracetic acid, BSPBio_001964, Diaminoethanetetra-acetic acid, KBioGR_001161, KBioSS_001498, ethylenediaminetetraacetic-acid, MLS001249457, BIDD:ER0565, DivK1c_000777, EDETIC ACID [WHO-DD], SPBio_000005, ethylenediamine-tetraacetic acid, CHEBI:4735, KBio1_000777, KBio2_001498, KBio2_004066, KBio2_006634, KBio3_001184, (Ethylenedintrilo)tetraacetic acid, ethylen-ediamine tetra-acetic acid, ethylene diamine tetra acetic acid, NINDS_000777, (ethylenedinitrilo) tetraacetic acid, CS-B1827, HY-Y0682, STR08855, Tox21_202736, BDBM50330325, HB5135, s6350, AKOS001574475, Glycine, (N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, labeled with carbon-14, (ethane-1,2-diyldinitrilo)tetraacetate, DB00974, CAS-60-00-4, IDI1_000777, USEPA/OPP Pesticide Code: 039101, ETHYLENE BIS (IMINODIACETIC ACID), NCGC00159485-03, NCGC00159485-04, NCGC00260284-01, 688-55-1, AC-10615, SMR000058776, SBI-0051360.P003, E0084, Ethylenediaminetetraacetic acid, 2Na (EDTA), Ethylenediaminetetraacetic acid, LR, >=98%, NS00003929, EN300-71613, C00284, D00052, ethylene-N,N'-biscarboxymethyl-N,N'-diglycine, Ethylenediaminetetraacetic acid, p.a., 98.0%, AB00053468_03, Ethylenediaminetetraacetic acid, >=98.0% (KT), A832566, N,N'-1,2-Ethanediylbis(N-carboxymethyl)-glycine, N,N'-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, N,N-1,2-Ethanediylbis[N-(carboxymethyl)]glycine, Q408032, SR-01000883946, Ethylenediaminetetraacetic Acid Sodium Salt Solution, Ethylenediaminetetraacetic acid, Cell Culture Reagent, J-610078, N, N-1,2-Ethanediylbis(N-(Carboxymethyl)Glycine), SR-01000883946-1, 3,6-Diazooctanedioic Acid, 3,6-bis(Carboxymethyl)-, 37C3C5E7-D921-445F-82D6-FEBF1AE5AEF5, Ethylenediaminetetraacetic acid, Electrophoresis Grade, Glycine, N, N'-1,2-Ethanediylbis-N-(Carboxymethyl), Z2588038976, Ethylenediaminetetraacetic acid, BioUltra, >=99.0% (KT), Ethylenediaminetetraacetic acid, 99.995% trace metals basis, Ethylenediaminetetraacetic acid, SAJ special grade, >=99.0%, Ethylenediaminetetraacetic acid, Vetec(TM) reagent grade, 98%, [{2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]acetic acid, edta disodium salt, cal-ex decalcifier, buffer solution, ph 10.00, sodium di ethylenediamine tetraacetate dihydrate, ethylenediamine tetraacetic acid, disodium salt dihydrate, ethylenediamine tetraacetic acid, disodium salt, standard solution, sodium di ethylenediamine tetraacetate standard solution, ethylenedinitrilo tetraacetic acid disodium, dihydrate, reagent, Edetic Acid, N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine), Diaminoethanetetra-acetic acid, Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, Acetic acid, (ethylenedinitrilo)tetra-, Acide ethylenediaminetetracetique, Celon A, Celon ATH, Cheelox, Cheelox BF acid, Chemcolox 340, Complexon II, 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethyl)-, Edathamil, Edta, Edta acid, Endrate, Ethylenediamine-N,N,N',N'-tetraacetic acid, Ethylenedinitrilotetraacetic acid, Hamp-ene acid, Havidote, Komplexon ii, Kyselina ethylendiamintetraoctova, Metaquest A, Nervanaid B acid, Nullapon B acid, Nullapon BF acid, Perma kleer 50 acid, Questex 4H, SEQ 100, Sequestrene AA, Sequestric acid, Sequestrol, Tetrine acid, Titriplex, Tricon bw, Trilon BW, Versene, Versene acid, Vinkeil 100, Warkeelate acid, (Ethylenedintrilo)tetraacetic acid, EDTA, free base, EDTA, free acid, Trilon BS, ([2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino)-acetic acid, Titriplex II, YD 30, Quastal Special, Acetic acid, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-, Gluma Cleanser, EDTA (chelating agent), Chelest 3A, ICRF 185, 2,2',2'',2'''-(Ethane-1,2-diyldinitrilo)te­traacetic acid, Dissolvine Z, 2-({2-[bis(carboxymet­hyl)amino]ethyl}(car­boxymethyl)ami­no)acetic acid, Diaminoethane-tetraacetic acid, Edetic acid, Ethylenedinitrilo-tetraacetic acid, Versene, EDTA, 2,2'',2'''',2''''''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid, Ethylenediaminetetraacetic acid, BioUltra, anhydrous, >=99% (titration), Glycine, N,N'-1, {2-ethanediylbis[N-(carboxymethyl)-,} disodium salt, {[2-(Bis-carboxymethyl-amino)-ethyl]-carboxymethyl-amino}-acetic acid(EDTA), 2-[2-[bis(2-hydroxy-2-oxoethyl)amino]ethyl-(2-hydroxy-2-oxoethyl)amino]ethanoic acid, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, Redi-Dri(TM), >=98%, Ethylenediamine-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetraacetic Acid-13C4 (|A-labels), Ethylenediaminetetraacetic acid, anhydrous, crystalline, BioReagent, suitable for cell culture, Ethylenediaminetetraacetic acid, anhydrous, free-flowing, powder, Redi-Dri(TM), ACS reagent, 99.4-100.6%, InChI=1/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20, N,N′-(Ethane-1,2-diyl)bis[N-(carboxymethyl)glycine], 2,2′,2′′,2′′′-(Ethane-1,2-diyldinitrilo)tetraacetic acid, EthyleneDiamineTetraAcetic acid, Diaminoethane-tetraacetic acid,



Ethylenediaminetetraacetic Acid (EDTA) is a colorless crystalline solid.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.
Ethylenediaminetetraacetic Acid (EDTA) is used in chemical analysis, to make detergents and cleaning compounds, and for many other uses.


Ethylenediaminetetraacetic Acid (EDTA) is a tetracarboxylic acid, an ethylenediamine derivative and a polyamino carboxylic acid.
Ethylenediaminetetraacetic Acid (EDTA) has a role as an antidote, a geroprotector, a chelator, a copper chelator and an anticoagulant.
Ethylenediaminetetraacetic Acid (EDTA) is a conjugate acid of an EDTA(2-).


Ethylenediaminetetraacetic Acid (EDTA) is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 tonnes per annum.
Ethylenediaminetetraacetic Acid (EDTA) is the commonly used abbreviation for (Ethylene­dinitrilo)­tetra­acetic Acid (also called Ethylene­diamine­tetra­acetic Acid or Edetic Acid).


The Disodium salt of Ethylenediaminetetraacetic Acid (EDTA) is the most commonly used form of this versatile organic complexing agent, which is used for the determination of many metal ions either by direct titration or by back-titration.
Adjustment of reaction conditions, either by controlling the pH or by use of masking agents, and selection of the appropriate indicator permits a wide variety of metal ions to be determined using Ethylenediaminetetraacetic Acid (EDTA).


Ethylenediaminetetraacetic Acid (EDTA) has a claw-like molecular structure that binds to heavy metals and other toxins.
Ethylenediaminetetraacetic Acid (EDTA) after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-insoluble solid, Ethylenediaminetetraacetic Acid (EDTA), is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH.


Ethylenediaminetetraacetic Acid (EDTA) is a Lead Chelator and Anti-coagulant.
The mechanism of action of Ethylenediaminetetraacetic Acid (EDTA) is as a Lead Chelating Activity and Calcium Chelating Activity.
The physiologic effect of Ethylenediaminetetraacetic Acid (EDTA) is by means of Decreased Coagulation Factor Activity.


Ethylenediaminetetraacetic Acid (EDTA) is a natural product found in Perilla frutescens, Apis cerana, and other organisms with data available.
Ethylenediaminetetraacetic Acid (EDTA) is a white odourless, colourless crystalline powder, with a melting point of 240C at which it decomposes.
Ethylenediaminetetraacetic Acid (EDTA) is insoluble in cold water, alcohol and general organic solvents, slightly soluble in water, soluble in sodium hydroxide, sodium carbonate and ammonia solution, soluble in boiling water.


The alkali metal salts are soluble in water.
Ethylenediaminetetraacetic Acid (EDTA) is an important complexing agent.
Ethylenediaminetetraacetic Acid (EDTA) is an organic compound with the chemical formula C10H16N2O8 and is a white powder under normal temperature and pressure.


Ethylenediaminetetraacetic Acid (EDTA) is a chelating agent that can bind with Mg2+, Ca2+, Mn2+, Fe2+ and other divalent metal ions.
Mg2+ is often used as an inhibitor of nucleases and proteases because most nucleases and some proteases require Mg2+.
Ethylenediaminetetraacetic Acid (EDTA) is also known to inhibit a range of metallopeptidases, the method of inhibition occurs via the chelation of the metal ion required for catalytic activity.


Ethylenediaminetetraacetic Acid (EDTA) can also be used to test for bioavailability of heavy metals in sediments.
Ethylenediaminetetraacetic Acid (EDTA), Disodium Salt, Dihydrate (Na2EDTA•2H2O), is a chelator of divalent metal cations.
Ethylenediaminetetraacetic Acid (EDTA) is suitable for biochemistry or molecular biology applications.


Ethylenediaminetetraacetic Acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium).
Ethylenediaminetetraacetic Acid (EDTA) has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities.
Ethylenediaminetetraacetic Acid (EDTA) is a common chelating agent, which means it binds strongly to metal ions to form stable, water-soluble compounds.
This function lends itself to widespread applications.



USES and APPLICATIONS of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: fertilisers and pH regulators and water treatment products.
Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: formulation of mixtures and formulation in materials.
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: pH regulators and water treatment products.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following areas: mining, scientific research and development and health services.
Ethylenediaminetetraacetic Acid (EDTA) is used for the manufacture of: and chemicals.
Ethylenediaminetetraacetic Acid (EDTA) is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.


Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.
Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: fertilisers.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: manufacturing of the substance and formulation of mixtures.
Ethylenediaminetetraacetic Acid (EDTA) is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following products: washing & cleaning products, coating products, polishes and waxes, biocides (e.g. disinfectants, pest control products), adhesives and sealants, fillers, putties, plasters, modelling clay, non-metal-surface treatment products, photo-chemicals, air care products, metal surface treatment products and textile treatment products and dyes.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints) and outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials).


Ethylenediaminetetraacetic Acid (EDTA) can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.
Ethylenediaminetetraacetic Acid (EDTA) is intended to be released from: packaging material for metal parts (releasing grease/corrosion inhibitors).


Ethylenediaminetetraacetic Acid (EDTA) can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones). Ethylenediaminetetraacetic Acid (EDTA) is intended to be released from scented: clothes, eraser, toys, paper products and CDs.


Ethylenediaminetetraacetic Acid (EDTA) is used in the following areas: agriculture, forestry and fishing and formulation of mixtures and/or re-packaging.
Release to the environment of Ethylenediaminetetraacetic Acid (EDTA) can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid, and of substances in closed systems with minimal release.


Other release to the environment of Ethylenediaminetetraacetic Acid (EDTA) is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediaminetetraacetic Acid (EDTA) is a chelating agent (chelating agents) that sequesters a variety of polyvalent cations.
Ethylenediaminetetraacetic Acid (EDTA) is used in pharmaceutical manufacturing and as a food additive.
Ethylenediaminetetraacetic Acid (EDTA) is the acid form of edetate, a chelating agent with anti-hypercalcemic and anticoagulant properties.


Ethylenediaminetetraacetic Acid (EDTA) binds calcium and heavy metal ions, forming soluble stable complexes which are readily excreted by the kidneys.
This results in a decrease in serum calcium levels.
Ethylenediaminetetraacetic Acid (EDTA) is also used as an anticoagulant for blood specimens and is applied as a treatment of lead poisoning.


Chelation therapy is a treatment that involves repeated intravenous (IV) administration of a chemical solution of Ethylenediaminetetraacetic Acid (EDTA).
Ethylenediaminetetraacetic Acid (EDTA) is used to treat acute and chronic lead poisoning by pulling toxins (including heavy metals such as lead, cadmium, and mercury) from the bloodstream.


The word "chelate" comes from the Greek root chele, which means "to claw."
The U.S. Food and Drug Administration (FDA) approved Ethylenediaminetetraacetic Acid (EDTA) chelation therapy as a treatment for lead and heavy metal poisoning.


Ethylenediaminetetraacetic Acid (EDTA) is also used as an emergency treatment for hypercalcemia (excessive calcium levels) and the control of ventricular arrhythmias (abnormal heart rhythms) associated with digitalis toxicity.
Ethylenediaminetetraacetic Acid (EDTA) is a medication used in the management and treatment of heavy metal toxicity.


Ethylenediaminetetraacetic Acid (EDTA) is in the chelating class of drugs.
Ethylenediaminetetraacetic Acid (EDTA) is used textiles and paper.
In industry, Ethylenediaminetetraacetic Acid (EDTA) is mainly used to sequester (bind or confine) metal ions in aqueous solution.


In the textile industry, Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Ethylenediaminetetraacetic Acid (EDTA) inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.


Food: In a similar manner, Ethylenediaminetetraacetic Acid (EDTA) is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.
Ethylenediaminetetraacetic Acid (EDTA) is used lead poisoning and heavy metal toxicity.


Chelation therapy using Ethylenediaminetetraacetic Acid (EDTA) is the medically-accepted treatment for lead poisoning.
Injected intravenously and once in the bloodstream, Ethylenediaminetetraacetic Acid (EDTA) traps lead and other metals, forming a compound that the body can eliminate in the urine.


The process generally takes 1 to 3 hours.
Other heavy metal poisonings treated with chelation include mercury, arsenic, aluminum, chromium, cobalt, manganese, nickel, selenium, zinc, tin, and thallium.


Chelating agents other than Ethylenediaminetetraacetic Acid (EDTA) are also used to clear several of these substances from the bloodstream.
Ethylenediaminetetraacetic Acid (EDTA) is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble.


Ethylenediaminetetraacetic Acid (EDTA) is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.
Eyedrops: Ethylenediaminetetraacetic Acid (EDTA) serves as a preservative (usually to enhance the action of another preservative such as benzalkonium chloride or thiomersal) in ocular preparations and eyedrops.


Cosmetics: In shampoos, cleaners, and other personal care products, Ethylenediaminetetraacetic Acid (EDTA) salts are used as a sequestering agent to improve their stability in air.
Ethylenediaminetetraacetic Acid (EDTA) is widely used, can be used for processing colour photographic materials bleach fixing bath washing, dyeing auxiliaries, textile processing auxiliaries, detergent, stabiliser, synthetic rubber and polymerization initiator.


Ethylenediaminetetraacetic Acid (EDTA) is used Agricultural Formulations, Bleaching (Pulp), Cleaning (Hard Surface), Cleaning (Industrial), Cleaning (Institutional), Cleaning (Metal), Cleaning (Offshore), Drilling/Completion Fluids,
Industrial Cleaning, Offshore Cleaning, Oilfield, Photography, and Textile.


Ethylenediaminetetraacetic Acid (EDTA) is predominantly used in agriculture, water treatment, pulp and paper industries and also used in the manufacture of cleaners and detergents
Ethylenediaminetetraacetic Acid (EDTA) is used chelating agents bind or capture trace amounts of iron, copper, manganese, calcium and other metals that occur naturally in many materials.


Such naturally occurring metals can cause chemical degradation, discoloration, scaling, instability, rancidity, ineffective cleaning performance and other problems.
In Metalworking industries Ethylenediaminetetraacetic Acid (EDTA) is used for surface preparation, metal cleaning, metal plating, and in metalworking fluids.


In Cleaning products, Ethylenediaminetetraacetic Acid (EDTA) is employed to remove hard water scale, soap film, and inorganic scales.
Ethylenediaminetetraacetic Acid (EDTA) is commonly used in a wide variety of cleaning products and formulations, including hard surface cleaners, laundry detergents, bactericidal cleaners, vehicle washes etc.


Ethylenediaminetetraacetic Acid (EDTA) finds many specialised uses in the biomedical labs, such as in veterinary ophthalmology as an anticollagenase to prevent the worsening of corneal ulcers in animals.
In tissue culture Ethylenediaminetetraacetic Acid (EDTA) is used as a chelating agent that binds to calcium and prevents joining of cadherins between cells, preventing clumping of cells grown in liquid suspension, or detaching adherent cells for passaging.


In histopathology, Ethylenediaminetetraacetic Acid (EDTA) can be used as a decalcifying agent making it possible to cut sections using a microtome once the tissue sample is demineralised.
Ethylenediaminetetraacetic Acid (EDTA) is also used to remove crud (corroded metals) from fuel rods in nuclear reactors.


Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine widely used in domestic and industrial applications.
Ethylenediaminetetraacetic Acid (EDTA) chelate metal divalent cations, such as calcium, magnesium, zinc, copper, and manganese, to form metal-EDTA complexes.


Ethylenediaminetetraacetic Acid (EDTA) is suitable for cleaning products and detergent formulations.
In the paper and pulp industry, Ethylenediaminetetraacetic Acid (EDTA) reduces the adverse effects of metal ions on bleaching.
As an antibacterial agent, Ethylenediaminetetraacetic Acid (EDTA) can remove calcium and magnesium divalent cations in the outer membrane and cause the loss of membrane lipopolysaccharide, making bacteria sensitive to bactericides.


Free Ethylenediaminetetraacetic Acid (EDTA) has an adverse effect on mammalian reproduction and development.
Ethylenediaminetetraacetic Acid (EDTA) can sequester ions in sediments that cause atherosclerosis, cancer and heart disease.
Ethylenediaminetetraacetic Acid (EDTA) reduces free radical reactions and oxidation processes, which helps to overcome cell membrane damage.


Ethylenediaminetetraacetic Acid (EDTA) can bind to calcium and reduce the risk of developing hypercalcemia in cancer patients.
The transmembrane Ethylenediaminetetraacetic Acid (EDTA) gradient method facilitates drug delivery, thereby enhancing drug retention and therapeutic effects and reducing levels of cytotoxicity.


Ethylenediaminetetraacetic Acid (EDTA) has a wide range of uses.
Ethylenediaminetetraacetic Acid (EDTA) can be used as bleaching fixative solution for color sensitive material washing processing, dyeing aid, fiber treatment aid, cosmetic additive, blood anticoagulant, detergent, stabilizer and synthetic rubber polymerization initiator.


Ethylenediaminetetraacetic Acid (EDTA) can form stable water-soluble complexes with alkaline earth metals, rare earth elements and transition metals.
In addition to sodium, there are ammonium salts and various salts of iron, magnesium, calcium, copper, manganese, zinc, cobalt and aluminum, all of which have different uses.


In addition, Ethylenediaminetetraacetic Acid (EDTA) can also be used to enable the rapid excretion of harmful radioactive metals from the body to play a detoxification role.
Ethylenediaminetetraacetic Acid (EDTA)'s also a water treatment agent.


Ethylenediaminetetraacetic Acid (EDTA) is also an important indicator, but it is used for titrating metals such as nickel and copper.
When used, Ethylenediaminetetraacetic Acid (EDTA) should be used together with ammonia to play the role of indicator.
Ethylenediaminetetraacetic Acid (EDTA) is used for in vitro anticoagulation of blood.


Ethylenediaminetetraacetic Acid (EDTA) is an anticoagulant additive for clinical blood testing.
Ethylenediaminetetraacetic Acid (EDTA) is used for pretreatment (anticoagulation) of blood samples during clinical blood collection and testing.
Ethylenediaminetetraacetic Acid (EDTA) is high solubility and fast anticoagulation.


Ethylenediaminetetraacetic Acid (EDTA) is mainly used to bind metal ions in aqueous solution making EDTA useful in a wide variety of uses as a chelating agent.
Ethylenediaminetetraacetic Acid (EDTA) is widely used to dissolve limescale.


In shampoos, cleaners, and other personal care products Ethylenediaminetetraacetic Acid (EDTA) salts are used as stabilizers.
Ethylenediaminetetraacetic Acid (EDTA) is added to some food as a preservative or stabilizer to prevent catalytic oxidative decoloration, which is catalyzed by metal ions.


In the pulp and paper industry, Ethylenediaminetetraacetic Acid (EDTA) inhibits the ability of metal ions, especially Mn2+, from catalyzing the disproportionation of hydrogen peroxide, which is used in "chlorine-free bleaching."
Ethylenediaminetetraacetic Acid (EDTA) decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification.


Ethylenediaminetetraacetic Acid (EDTA) can alleviate the liver fibrosis.
Ethylenediaminetetraacetic Acid (EDTA) can be used for coronary artery disease and neural system disease research.
Ethylenediaminetetraacetic Acid (EDTA) can also be used to remove the inhibition of heavy metal ions on enzymes.


Chelating agent, Ethylenediaminetetraacetic Acid (EDTA) is used in many enzyme buffers and at higher concentrations, as enzyme inactivator
Detergent uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) can be used as a labeling buffer component for washing during cell lysis {155}.


Supplements: Ethylenediaminetetraacetic Acid (EDTA) is used as a supplement for synthetic tubal fluid culture 1 (SOFC1) medium for embryo culture.
Ethylenediaminetetraacetic Acid (EDTA) is used as a complexing agent for many cations.
Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities and used to remove excess iron from the body.


Ethylenediaminetetraacetic Acid (EDTA) acts as a sequestering agent in cosmetic products.
Ethylenediaminetetraacetic Acid (EDTA) is used as a complexing agent for many cations.
Ethylenediaminetetraacetic Acid (EDTA) prevents metal ion impurities and used to remove excess iron from the body.


Ethylenediaminetetraacetic Acid (EDTA) acts as a sequestering agent in cosmetic products.
For example, Ethylenediaminetetraacetic Acid (EDTA) may be added as a stabilizer to foods or cosmetic products in order to sequester metal ions that would otherwise act as catalysts towards the production of harmful or undesirable products (e.g. discoloration, carcinogens).


In other cases, Ethylenediaminetetraacetic Acid (EDTA) can improve the solubility of otherwise insoluble metals; for example, in agricultural applications, EDTA can improve iron bioavailability to plants.
Ethylenediaminetetraacetic Acid (EDTA) has also been used for chelation therapy, to treat heavy metal poisoning.


Ethylenediaminetetraacetic Acid (EDTA) products are used for hair, skin, chelation, endodontics, in food, in skincare, shampoo and dentistry.
Ethylenediaminetetraacetic Acid (EDTA) is a representative chelating agent.
Ethylenediaminetetraacetic Acid (EDTA) is an important complexing agent.


-Cell sorting analysis uses of Ethylenediaminetetraacetic Acid (EDTA):
Firstly, Ethylenediaminetetraacetic Acid (EDTA) is used single-cell suspension of spleen dendritic cells for magnetic bead cell sorting.
Secondly, incubate EpCAM + cells and FITC-labeled antibodies for cell sorting analysis.


-The applications of Ethylenediaminetetraacetic acid (EDTA) have been reported as following:
Complexing agent uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is a hydrophilic gold chelator that converts metal ions into inactive, cyclized metal complexes.
Therefore, Ethylenediaminetetraacetic Acid (EDTA) can be used in industry to solve metal pollutants.


-Blood anticoagulant uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) cannot be absorbed by the gastrointestinal tract.
Intravenous injection of sodium EDTA causes hypocalcemic hand-foot twitching.

Ethylenediaminetetraacetic Acid (EDTA) is commonly used for plasma or molecular diagnostics, and calcium chelation.
Ethylenediaminetetraacetic Acid (EDTA) can be used as an anticoagulant in blood cell count and cell morphology analysis.


-Other key applications for Ethylenediaminetetraacetic Acid (EDTA) include:
*In Photography as a bleach in photographic film processing.
*In the manufacturing of paper to maximize bleaching efficiency during pulping, prevent brightness reversion, and protect bleach potency.
*In Scale removal and prevention - to clean calcium and other types of scale from boilers, evaporators, heat exchangers, filter cloths, and glass-lined kettles.
*Water treatment - to control water hardness and scale-forming calcium and magnesium ions and to prevent scale formation.


-Laboratory applications of Ethylenediaminetetraacetic Acid (EDTA):
In the laboratory, Ethylenediaminetetraacetic Acid (EDTA) is widely used for scavenging metal ions: In biochemistry and molecular biology, ion depletion is commonly used to deactivate metal-dependent enzymes, either as an assay for their reactivity or to suppress damage to DNA, proteins, and polysaccharides.

Ethylenediaminetetraacetic Acid (EDTA) also acts as a selective inhibitor against dNTP hydrolyzing enzymes (Taq polymerase, dUTPase, MutT), liver arginase and horseradish peroxidase independently of metal ion chelation.

These findings urge the rethinking of the utilisation of Ethylenediaminetetraacetic Acid (EDTA) as a biochemically inactive metal ion scavenger in enzymatic experiments.

In analytical chemistry, Ethylenediaminetetraacetic Acid (EDTA) is used in complexometric titrations and analysis of water hardness or as a masking agent to sequester metal ions that would interfere with the analyses.


-Water softener uses of Ethylenediaminetetraacetic Acid (EDTA):
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on Ethylenediaminetetraacetic Acid (EDTA) and related complexants to bind Ca2+, Mg2+, as well as other metal ions.

Once bound to Ethylenediaminetetraacetic Acid (EDTA), these metal complexes are less likely to form precipitates or to interfere with the action of the soaps and detergents.
For similar reasons, cleaning solutions often contain Ethylenediaminetetraacetic Acid (EDTA).

In a similar manner Ethylenediaminetetraacetic Acid (EDTA) is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.
The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using Ethylenediaminetetraacetic Acid (EDTA).

This property is useful in agriculture including hydroponics. However, given the pH dependence of ligand formation, Ethylenediaminetetraacetic Acid (EDTA) is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.


-Scrubbing uses of Ethylenediaminetetraacetic Acid (EDTA):
Aqueous [Fe(EDTA)]− is used for removing ("scrubbing") hydrogen sulfide from gas streams.
This conversion is achieved by oxidising the hydrogen sulfide to elemental sulfur, which is non-volatile:
2 [Fe(EDTA)]− + H2S → 2 [Fe(EDTA)]2− + S + 2 H+

In this application, the iron(III) centre is reduced to its iron(II) derivative, which can then be reoxidised by air.
In similar manner, nitrogen oxides are removed from gas streams using [Fe(EDTA)]2−.
The oxidising properties of [Fe(EDTA)]− are also exploited in photography, where it is used to solubilise silver particles.


-Analysis uses of Ethylenediaminetetraacetic Acid (EDTA):
In medical diagnosis and organ function tests (here, kidney function test), the chromium(III) complex [Cr(EDTA)]− (as radioactive chromium-51 (51Cr)) is administered intravenously and its filtration into the urine is monitored.

This method is useful for evaluating glomerular filtration rate (GFR) in nuclear medicine.
Ethylenediaminetetraacetic Acid (EDTA) is used extensively in the analysis of blood.
Ethylenediaminetetraacetic Acid (EDTA) is an anticoagulant for blood samples for CBC/FBCs, where the EDTA chelates the calcium present in the blood specimen, arresting the coagulation process and preserving blood cell morphology.

Tubes containing Ethylenediaminetetraacetic Acid (EDTA) are marked with lavender (purple) or pink tops.
Ethylenediaminetetraacetic Acid (EDTA) is also in tan top tubes for lead testing and can be used in royal blue top tubes for trace metal testing.
Ethylenediaminetetraacetic Acid (EDTA) is a slime dispersant, and has been found to be highly effective in reducing bacterial growth during implantation of intraocular lenses (IOLs).


-Alternative medicine uses of Ethylenediaminetetraacetic Acid (EDTA):
Some alternative practitioners believe Ethylenediaminetetraacetic Acid (EDTA) acts as an antioxidant, preventing free radicals from injuring blood vessel walls, therefore reducing atherosclerosis.
These ideas are unsupported by scientific studies, and seem to contradict some currently accepted principles.
The U.S. FDA has not approved it for the treatment of atherosclerosis.


-Ion-exchange chromatography uses of Ethylenediaminetetraacetic Acid (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) was used in separation of the lanthanide metals by ion-exchange chromatography.
Perfected by F. H. Spedding et al. in 1954, the method relies on the steady increase in stability constant of the lanthanide Ethylenediaminetetraacetic Acid (EDTA) complexes with atomic number.

Using sulfonated polystyrene beads and Cu2+ as a retaining ion, Ethylenediaminetetraacetic Acid (EDTA) causes the lanthanides to migrate down the column of resin while separating into bands of pure lanthanides.
The lanthanides elute in order of decreasing atomic number.

Due to the expense of this method, relative to countercurrent solvent extraction, ion exchange is now used only to obtain the highest purities of lanthanides (typically greater than 99.99%).


-Medicine uses of Ethylenediaminetetraacetic Acid (EDTA):
Sodium calcium edetate, an Ethylenediaminetetraacetic Acid (EDTA) derivative, is used to bind metal ions in the practice of chelation therapy, such as for treating mercury and lead poisoning.

Ethylenediaminetetraacetic Acid (EDTA) is used in a similar manner to remove excess iron from the body.
This therapy is used to treat the complication of repeated blood transfusions, as would be applied to treat thalassaemia.


-Dentistry uses of Ethylenediaminetetraacetic Acid (EDTA):
Dentists and endodontists use Ethylenediaminetetraacetic Acid (EDTA) solutions to remove inorganic debris (smear layer) and lubricate the root canals in endodontics.

This procedure helps prepare root canals for obturation.
Furthermore, Ethylenediaminetetraacetic Acid (EDTA) solutions with the addition of a surfactant loosen up calcifications inside a root canal and allow instrumentation (canal shaping) and facilitate apical advancement of a file in a tight or calcified root canal towards the apex.



PHYSICAL PROPERTIES OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
The chemical names of ethylenediaminetetraacetic acid include Ethylenediamine tetraacetic acid, (Ethylenedinitrilo) tetraacetic acid, Edetic acid and EDTA.
EDTA is white powder, which is soluble in sodium hydroxide, sodium carbonate and ammonia solution, and 160 parts of boiling water, and slightly soluble in cold water, insoluble in ethanol and general organic solvents.
It can form extremely stable water-soluble complexes with alkali metals, rare earth elements and transition metals.
EDTA decompose above its melting point 240°C.



SOLUBILITY OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is soluble in sodium hydroxide, sodium carbonate, ammonia solution, acid and common organic solvents.
Ethylenediaminetetraacetic Acid (EDTA) is slightly soluble in water.



PHYSICAL AND CHEMICAL PROPERTIES OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Ethylenediaminetetraacetic Acid (EDTA) is used white odorless, tasteless, colorless crystalline powder, melting point 250℃ (decomposition).
Ethylenediaminetetraacetic Acid (EDTA) is insoluble in ethanol and general organic solvents, slightly soluble in cold water, soluble in aqueous solutions of sodium hydroxide, sodium carbonate and ammonia.

Ethylenediaminetetraacetic Acid (EDTA) can dissolve in more than 5% of inorganic acid, can also dissolve in ammonia and 160 parts of boiling water.
Ethylenediaminetetraacetic Acid (EDTA)'s alkali metal salts are soluble in water.



MOLARITY OF ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
Molarity is best used in expressing Ethylenediaminetetraacetic Acid (EDTA) concentration, because the reaction involves the complexation of one metal ion by one EDTA molecule or ion, whether the free acid form of EDTA or one of its more soluble Sodium salts is used.
The general reaction involving the Disodium salt is:

EDTA2- + Mn+ → [EDTA-M]+n-2
where M = Ca, Mg, Cd, Mn, Ni, Al, Zn, Bi, Co, Cu, or other metal ion

An indicator is added that forms a colored complex with some of the metal ion being determined.
When the endpoint is reached, all of the free metal ion has been complexed by the Ethylenediaminetetraacetic Acid (EDTA).
The last addition of Ethylenediaminetetraacetic Acid (EDTA) then removes the metal ion from its complex with the indicator, producing a color change.

The relative strength of the Ethylenediaminetetraacetic Acid (EDTA)-metal ion complex compared to that of the indicator-metal ion complex determines whether a direct titration or a back-titration is applicable.

Ethylenediaminetetraacetic Acid (EDTA) is most commonly used to determine hardness (i.e., Calcium and Magnesium ions) in water, where the pH must be approximately 10 and is usually controlled by adding a buffer such as Water Hardness Buffer.

Water Hardness Indicator (Eriochrome Black T), Eriochrome Blue Black R, Calmagite, and Murexide are used for hardness or Calcium determinations using Ethylenediaminetetraacetic Acid (EDTA).



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
CAS Number: 60-00-4
Molecular Weight: 292.24
Beilstein: 1716295
EC Number: 200-449-4
MDL Number: MFCD00003541
Physical State: Powder
Color: White
Odor: Odorless
Melting Point/Freezing Point: Melting point/range: 250 °C - dec.
Initial Boiling Point and Boiling Range: No data available
Flammability (solid, gas): No data available
Upper/Lower Flammability or Explosive Limits: No data available
Flash Point: Not applicable
Autoignition Temperature: No data available
Decomposition Temperature: > 220 °C

pH: 2.5 at 10 g/l at 23 °C
Viscosity:
Kinematic Viscosity: No data available
Dynamic Viscosity: No data available
Water Solubility: 0.4 g/l at 20 °C
Partition Coefficient (n-octanol/water): No data available
Vapor Pressure: No data available
Density: 1.46 g/cm³ at 20 °C
Relative Density: No data available
Relative Vapor Density: No data available
Particle Characteristics: No data available
Explosive Properties: No data available
Oxidizing Properties: None
Other Safety Information:
Dissociation constant: 8.85 - 10.44 at 20 °C
Molecular Weight: 292.24 g/mol

XLogP3-AA: -5.9
Hydrogen Bond Donor Count: 4
Hydrogen Bond Acceptor Count: 10
Rotatable Bond Count: 11
Exact Mass: 292.09066547 g/mol
Monoisotopic Mass: 292.09066547 g/mol
Topological Polar Surface Area: 156 Ų
Heavy Atom Count: 20
Formal Charge: 0
Complexity: 316
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1

Compound Is Canonicalized: Yes
CAS No. 60-00-4
EC No. 200-449-4
Formula: (HO2CCH2)2NCH­2CH2N(CH2CO2H)2
Molecular weight: 292.24
Appearance: white crystalline solid.
Relative density: 0.86 g/cm3
Melting Point: 220C (428F)
Solubility: Very slightly soluble in cold water.
pH (1%): 2.5
Chemical Formula: C10H16N2O8
Molar Mass: 292.244 g·mol⁻¹
Appearance: Colorless crystals
Density: 0.860 g cm⁻³ (at 20 °C)
Log P: -0.836
Acidity (pKa): 2.0, 2.7, 6.16, 10.26

Thermochemistry:
Standard Enthalpy of Formation (ΔfH⦵298): -1765.4 to -1758.0 kJ mol⁻¹
Standard Enthalpy of Combustion (ΔcH⦵298): -4461.7 to -4454.5 kJ mol⁻¹
CAS Number: 65501-24-8
Packing: 500g/bottle
Appearance: White crystal powder
Chemical Properties: Odorless, soluble in water, easy to absorb moisture
Molecular Weight: 442.56
pH Value: 7.3±1 (5% aqueous solution, g/ml)
Solubility in Water: ≥60% (g/ml, 25℃)
Validity Period: 3 years
Storage Conditions: Dry and sealed at room temperature.



FIRST AID MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Description of first-aid measures:
*General advice:
Show this material safety data sheet to the doctor in attendance.
*If inhaled:
After inhalation:
Fresh air.
*In case of skin contact:
Take off immediately all contaminated clothing.
Rinse skin with water/ shower.
*In case of eye contact:
After eye contact:
Rinse out with plenty of water.
Call in ophthalmologist.
Remove contact lenses.
*If swallowed:
After swallowing:
Immediately make victim drink water (two glasses at most).
Consult a physician.
-Indication of any immediate medical attention and special treatment needed:
No data available



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Environmental precautions:
Do not let product enter drains.
-Methods and materials for containment and cleaning up:
Cover drains.
Collect, bind, and pump off spills.
Observe possible material restrictions.
Take up dry.
Dispose of properly.
Clean up affected area.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Extinguishing media:
*Suitable extinguishing media:
Carbon dioxide (CO2)
Foam
Dry powder
*Unsuitable extinguishing media:
For this substance/mixture no limitations of extinguishing agents are given.
-Further information:
Suppress (knock down) gases/vapors/mists with a water spray jet.
Prevent fire extinguishing water from contaminating surface water or the ground water system.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Control parameters:
--Ingredients with workplace control parameters:
-Exposure controls:
--Personal protective equipment:
*Eye/face protection:
Use equipment for eye protection.
Safety glasses
*Skin protection:
Full contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
Splash contact:
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: 480 min
*Body Protection:
protective clothing
*Respiratory protection:
Recommended Filter type: Filter type P2
-Control of environmental exposure:
Do not let product enter drains.



HANDLING and STORAGE of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Conditions for safe storage, including any incompatibilities:
*Storage conditions:
Tightly closed.
Dry.



STABILITY and REACTIVITY of ETHYLENEDIAMINETETRAACETIC ACID (EDTA):
-Chemical stability:
The product is chemically stable under standard ambient conditions (room temperature) .
-Conditions to avoid:
no information available

Ethylenediaminetetraacetic acid disodium salt, often abbreviated as Ethylenediaminetetraacetic acid disodium salt, is a chemical compound with the molecular formula C10H14N2Na2O8.
Ethylenediaminetetraacetic acid disodium salt is a synthetic organic compound derived from ethylenediamine and acetic acid.
Ethylenediaminetetraacetic acid disodium salt is a chelating agent, which means it can form stable complexes with metal ions by coordinating with their positively charged ions.

CAS Number: 6381-92-6
EC Number: 205-358-3



APPLICATIONS


Ethylenediaminetetraacetic acid disodium salt (Ethylenediaminetetraacetic acid disodium salt) is widely used in the field of analytical chemistry.
In analytical chemistry, Ethylenediaminetetraacetic acid disodium salt serves as a chelating agent to determine metal ion concentrations through complexometric titrations.
Ethylenediaminetetraacetic acid disodium salt is used to sequester and remove metal ions from water in various industrial and laboratory applications.

In the food and beverage industry, Ethylenediaminetetraacetic acid disodium salt is utilized as a food additive (E385) to preserve the color and flavor of processed foods.
Ethylenediaminetetraacetic acid disodium salt prevents the oxidation of food components by binding to metal ions that catalyze oxidation reactions.
Ethylenediaminetetraacetic acid disodium salt is employed in pharmaceuticals as a stabilizing agent and preservative in some medications.

In the cosmetics and personal care industry, it serves as a stabilizer in various products, including creams and lotions.
Medical applications include the use of Ethylenediaminetetraacetic acid disodium salt in chelation therapy to treat heavy metal poisoning.
Ethylenediaminetetraacetic acid disodium salt can effectively bind to heavy metal ions, such as lead and mercury, aiding in their removal from the body.
Ethylenediaminetetraacetic acid disodium salt is used as an anticoagulant in blood collection tubes to prevent clotting and maintain sample integrity.

Ethylenediaminetetraacetic acid disodium salt is a common component in many laboratory reagents and buffers used in molecular biology and biochemistry research.
In the textiles industry, Ethylenediaminetetraacetic acid disodium salt is utilized as a color-removing agent in the dyeing and printing processes.
Ethylenediaminetetraacetic acid disodium salt is employed as a metal ion control agent in pulp and paper manufacturing to improve paper quality.

In the photography industry, Ethylenediaminetetraacetic acid disodium salt is used in photographic development solutions to prevent the formation of unwanted precipitates.
Ethylenediaminetetraacetic acid disodium salt plays a role in soil science, where it is used to chelate metal ions in soil samples for analysis.
In the oil and gas industry, it helps prevent scale formation by sequestering metal ions that can cause scaling in pipelines and equipment.

Ethylenediaminetetraacetic acid disodium salt is a key ingredient in some household cleaning products, contributing to their efficacy in removing mineral deposits.
In the electronics industry, it is used as a cleaning agent to remove metal ion contaminants from semiconductor surfaces.

Ethylenediaminetetraacetic acid disodium salt is added to some shampoos and personal care products to improve product stability and shelf life.
Ethylenediaminetetraacetic acid disodium salt is used in the manufacture of detergents to enhance their performance by binding to metal ions that interfere with cleaning.
Ethylenediaminetetraacetic acid disodium salt is employed in water treatment plants to reduce the effects of hard water and prevent scale buildup in pipes.

Ethylenediaminetetraacetic acid disodium salt is used in the preservation of archaeological and historical artifacts to prevent metal corrosion.
In the agricultural industry, it can be used to correct nutrient deficiencies in plants by chelating essential metals.
Ethylenediaminetetraacetic acid disodium salt is employed in the development of nanomaterials and nanoparticles for various applications.

Ethylenediaminetetraacetic acid disodium salt is commonly used in the pharmaceutical industry to improve the stability of certain medications.
In the textile industry, Ethylenediaminetetraacetic acid disodium salt serves as a color-removing agent and as a component in dyeing processes.
Ethylenediaminetetraacetic acid disodium salt finds application in the manufacture of soaps and detergents to enhance their cleaning efficiency.

In the cosmetics and personal care sector, it is utilized to maintain product stability and prevent rancidity.
Ethylenediaminetetraacetic acid disodium salt is employed in the preservation of art and historical artifacts to prevent metal corrosion.
In the oil drilling industry, it is added to drilling fluids to control the adverse effects of metal ions.

Ethylenediaminetetraacetic acid disodium salt plays a role in water treatment by sequestering metal ions that can cause scale buildup.
In the field of molecular biology, Ethylenediaminetetraacetic acid disodium salt is used as an essential component in DNA and RNA extraction.

Ethylenediaminetetraacetic acid disodium salt contributes to the formulation of hemodialysis solutions to remove excess metals from the blood.
Ethylenediaminetetraacetic acid disodium salt is added to anticoagulant solutions used in blood collection tubes to maintain sample quality.

Ethylenediaminetetraacetic acid disodium salt helps improve the stability of certain photographic chemicals and prevents precipitation.
In the automotive industry, it is used as an ingredient in automotive cooling systems to inhibit corrosion.

Ethylenediaminetetraacetic acid disodium salt can be found in some eye drops and ointments, contributing to their preservation.
Ethylenediaminetetraacetic acid disodium salt is employed in the electronics industry for cleaning and descaling semiconductor surfaces.
Ethylenediaminetetraacetic acid disodium salt is utilized in the production of specialty chemicals, including catalysts and reagents.

In the mining and mineral processing industry, it is added to flotation reagents for ore separation.
Ethylenediaminetetraacetic acid disodium salt is used in the manufacture of cleaning agents for removing mineral deposits.

In the agriculture sector, it may be employed as a micronutrient fertilizer.
Ethylenediaminetetraacetic acid disodium salt plays a role in the formulation of certain veterinary medications.
In the construction industry, it is used to improve the workability of cement and concrete mixtures.

Ethylenediaminetetraacetic acid disodium salt is used in the preservation of samples in laboratories and research settings.
Ethylenediaminetetraacetic acid disodium salt contributes to the stability of certain chemical solutions used in analytical chemistry.
In the food and beverage industry, it is employed as a sequestrant to enhance the quality of processed foods.

Ethylenediaminetetraacetic acid disodium salt is sometimes added to swimming pool water to control metal ion content and prevent staining.
Ethylenediaminetetraacetic acid disodium salt serves as a valuable tool in environmental chemistry for the analysis of metal ion concentrations in natural water sources.

In the pharmaceutical industry, Ethylenediaminetetraacetic acid disodium salt is used to enhance the stability of certain medications and prevent degradation caused by metal ions.
Ethylenediaminetetraacetic acid disodium salt plays a crucial role in analytical chemistry, particularly in complexometric titrations to determine metal ion concentrations in samples.
Ethylenediaminetetraacetic acid disodium salt is employed in the food and beverage industry as a food additive (E385) to maintain product color and flavor.
Ethylenediaminetetraacetic acid disodium salt is added to canned and packaged foods to prevent the deterioration of food quality due to metal-induced oxidation reactions.

Ethylenediaminetetraacetic acid disodium salt is utilized in the cosmetics and personal care industry to stabilize and extend the shelf life of various products.
In medical applications, Ethylenediaminetetraacetic acid disodium salt is used as an anticoagulant in blood collection tubes to ensure the integrity of blood samples.
Ethylenediaminetetraacetic acid disodium salt is a vital component in chelation therapy, a medical treatment for heavy metal poisoning, where it binds to and facilitates the removal of toxic metal ions from the body.
Ethylenediaminetetraacetic acid disodium salt is applied in the preservation of historical artifacts and artworks to prevent corrosion and degradation.
In the oil and gas industry, Ethylenediaminetetraacetic acid disodium salt is used to prevent scale formation by sequestering metal ions that can cause scaling in pipelines and equipment.

Ethylenediaminetetraacetic acid disodium salt contributes to the removal of metal contaminants from semiconductor surfaces in the electronics industry.
Ethylenediaminetetraacetic acid disodium salt is used in soil science to chelate metal ions in soil samples for analysis.

In the pulp and paper industry, it acts as a metal ion control agent to enhance paper quality and prevent coloration.
Ethylenediaminetetraacetic acid disodium salt plays a role in the development of nanomaterials and nanoparticles for various applications.
Ethylenediaminetetraacetic acid disodium salt is used as a cleaning agent in the electronics industry to remove metal ion contaminants from circuit boards.

Ethylenediaminetetraacetic acid disodium salt is employed in the mining industry as a flotation reagent to assist in ore separation.
In the automotive sector, it is added to automotive cooling systems to prevent corrosion and scale formation.
Ethylenediaminetetraacetic acid disodium salt is an essential component in laboratory reagents and buffers used in molecular biology and biochemistry research.
Ethylenediaminetetraacetic acid disodium salt finds application in water treatment plants to reduce the effects of hard water and prevent scale buildup in pipes.

Ethylenediaminetetraacetic acid disodium salt is used as a component in some household cleaning products to improve their effectiveness in removing mineral deposits.
In photography, it helps maintain the stability of photographic development solutions by preventing precipitation.
Ethylenediaminetetraacetic acid disodium salt is added to some shampoos and personal care products to improve product stability and shelf life.

Ethylenediaminetetraacetic acid disodium salt is employed in the textile industry to remove metal ions and enhance the dyeing process.
Ethylenediaminetetraacetic acid disodium salt is utilized in agriculture as a chelated micronutrient fertilizer.
In the construction industry, it improves the workability of cement and concrete mixtures.
Ethylenediaminetetraacetic acid disodium salt plays a vital role in a wide range of scientific, industrial, and medical applications, thanks to its versatile chelation properties.

In the automotive industry, Ethylenediaminetetraacetic acid disodium salt is added to automotive cooling systems as a corrosion inhibitor to protect engine components from metal-induced corrosion and scale buildup.
Ethylenediaminetetraacetic acid disodium salt is used in the preparation of laboratory reagents and buffers for biochemical and molecular biology research to ensure the accuracy of experiments.
Ethylenediaminetetraacetic acid disodium salt is employed in the mining and metallurgy industry to assist in the separation of valuable minerals from ore by binding to and facilitating the removal of unwanted metal ions.

Ethylenediaminetetraacetic acid disodium salt finds application in the electronics industry for cleaning semiconductor surfaces and preventing metal ion contamination during manufacturing.
In the water treatment field, Ethylenediaminetetraacetic acid disodium salt is utilized to sequester metal ions that can lead to the formation of scale deposits and reduce the efficiency of water systems.
Ethylenediaminetetraacetic acid disodium salt plays a role in the development of nanomaterials and nanoparticles, contributing to advancements in nanotechnology and materials science.

Ethylenediaminetetraacetic acid disodium salt is used in analytical chemistry as a complexing agent to determine the concentration of metal ions in environmental samples, such as water and soil.
Ethylenediaminetetraacetic acid disodium salt is employed in the cosmetics and personal care industry to maintain the stability and quality of various products, including creams, lotions, and shampoos.
In the construction sector, Ethylenediaminetetraacetic acid disodium salt is used to enhance the workability of cement and concrete mixtures, improving their performance and durability.
Ethylenediaminetetraacetic acid disodium salt is a key ingredient in certain veterinary medications, ensuring the safety and effectiveness of these pharmaceutical products.

Ethylenediaminetetraacetic acid disodium salt is used in the oil and gas industry to control the buildup of scale deposits in pipelines and equipment, which can obstruct oil flow.

Ethylenediaminetetraacetic acid disodium salt contributes to the preservation of archaeological artifacts, protecting them from metal corrosion and environmental degradation.
In the pulp and paper industry, it serves as a metal ion control agent to maintain paper quality and prevent discoloration during production.
Ethylenediaminetetraacetic acid disodium salt is utilized in the photography industry to stabilize photographic development solutions, preventing unwanted precipitation.

Ethylenediaminetetraacetic acid disodium salt plays a role in soil remediation efforts by assisting in the removal of heavy metal contaminants from polluted soil.
Ethylenediaminetetraacetic acid disodium salt is added to some cleaning products and detergents to enhance their effectiveness in removing mineral deposits, such as limescale.
In agriculture, Ethylenediaminetetraacetic acid disodium salt is used as a micronutrient fertilizer to deliver essential metals to plants in a form that is readily accessible.

Ethylenediaminetetraacetic acid disodium salt finds application in the food and beverage industry as a sequestrant to maintain the quality of processed foods and prevent undesirable color changes.
Ethylenediaminetetraacetic acid disodium salt is employed in the automotive radiator repair industry to remove mineral deposits and improve the cooling system's efficiency.
Ethylenediaminetetraacetic acid disodium salt is used as a stabilizing agent in the formulation of certain eye drops and ointments, ensuring their safety and efficacy.
In water softening systems, Ethylenediaminetetraacetic acid disodium salt is used to replace hard water ions with sodium ions, reducing the effects of hard water on appliances and plumbing.

Ethylenediaminetetraacetic acid disodium salt is applied in chemical analysis as a masking agent to selectively protect specific metal ions from interference during analysis.
Ethylenediaminetetraacetic acid disodium salt can be used to adjust the pH of solutions and maintain the desired pH range in various chemical processes.
Ethylenediaminetetraacetic acid disodium salt is utilized in laboratory settings to chelate metal ions in samples, preventing their interference with analytical techniques.
The versatile chelation properties of Ethylenediaminetetraacetic acid disodium salt continue to make it an indispensable chemical in numerous scientific, industrial, and environmental applications.



DESCRIPTION


Ethylenediaminetetraacetic acid disodium salt, often abbreviated as Ethylenediaminetetraacetic acid disodium salt, is a chemical compound with the molecular formula C10H14N2Na2O8.
Ethylenediaminetetraacetic acid disodium salt is a synthetic organic compound derived from ethylenediamine and acetic acid.
Ethylenediaminetetraacetic acid disodium salt is a chelating agent, which means it can form stable complexes with metal ions by coordinating with their positively charged ions.

Ethylenediaminetetraacetic acid disodium salt, also known as Ethylenediaminetetraacetic acid disodium salt, is a synthetic organic compound.
Ethylenediaminetetraacetic acid disodium salt is derived from ethylenediamine and acetic acid through a series of chemical reactions.

Ethylenediaminetetraacetic acid disodium salt has a white, crystalline appearance and is water-soluble.
The chemical formula of Ethylenediaminetetraacetic acid disodium salt is C10H14N2Na2O8, indicating its composition of carbon, hydrogen, nitrogen, sodium, and oxygen atoms.

Ethylenediaminetetraacetic acid disodium salt is a chelating agent, meaning it can form stable complexes with metal ions.
Ethylenediaminetetraacetic acid disodium salt can bind to metal ions by coordinating with their positively charged ions.
In analytical chemistry, Ethylenediaminetetraacetic acid disodium salt serves as a titrant in complexometric titrations to determine metal ion concentrations.
In the food and beverage industry, Ethylenediaminetetraacetic acid disodium salt is used as a food additive (E385) to preserve product color and flavor.

Ethylenediaminetetraacetic acid disodium salt can prevent the oxidation of food components by binding to metal ions that catalyze oxidation reactions.
Ethylenediaminetetraacetic acid disodium salt is used in the pharmaceutical industry as a stabilizing agent and preservative in some medications.

In the cosmetics and personal care sector, Ethylenediaminetetraacetic acid disodium salt is utilized in various products as a stabilizer.
Medical applications include the use of Ethylenediaminetetraacetic acid disodium salt in chelation therapy to treat heavy metal poisoning.

Ethylenediaminetetraacetic acid disodium salt is also employed as an anticoagulant in blood collection tubes to prevent clotting.
In the detergents and cleaning industry, Ethylenediaminetetraacetic acid disodium salt enhances the performance of laundry detergents by binding to metal ions that can interfere with the cleaning process.
Ethylenediaminetetraacetic acid disodium salt plays a crucial role in water treatment by sequestering and removing metal ions to prevent contamination.
Ethylenediaminetetraacetic acid disodium salt is an odorless and tasteless substance.
Ethylenediaminetetraacetic acid disodium salt is highly soluble in water, resulting in easy preparation of aqueous solutions.

Ethylenediaminetetraacetic acid disodium salt is considered safe for use in many applications when used as directed.
Its ability to form stable metal complexes makes it a valuable tool for analytical chemistry.
Ethylenediaminetetraacetic acid disodium salt is an important component in the preservation of certain foods and beverages.

Its presence in cosmetics and pharmaceuticals helps maintain product quality and stability.
Chelation therapy using Ethylenediaminetetraacetic acid disodium salt can be an effective treatment for heavy metal poisoning.
In the detergent industry, it ensures that laundry products effectively remove stains and soils.

Ethylenediaminetetraacetic acid disodium salt, with its versatile applications, continues to be a valuable chemical compound in various fields.
The consistent use of Ethylenediaminetetraacetic acid disodium salt is essential in maintaining the quality and safety of products in which it is employed.



PROPERTIES


Chemical Formula: C10H14N2Na2O8
Molar Mass: Approximately 372.24 g/mol
Appearance: White, crystalline powder
Solubility: Highly soluble in water
Melting Point: Decomposes at high temperatures
Density: 1.01 g/cm³ (approximate)
pH Level: Typically, a 0.1 M solution of Ethylenediaminetetraacetic acid disodium salt has a pH of around 4.0 to 5.0.
Odor: Odorless
Taste: Tasteless
Hygroscopic: It can absorb moisture from the air.



FIRST AID


Inhalation:

If Ethylenediaminetetraacetic acid disodium salt dust or particles are inhaled and respiratory distress occurs, immediately move the affected person to an area with fresh air.
Keep the person calm and encourage them to breathe slowly and deeply.
If breathing difficulties persist or worsen, seek medical attention promptly.


Skin Contact:

In case of skin contact with Ethylenediaminetetraacetic acid disodium salt, remove contaminated clothing and rinse the affected area thoroughly with copious amounts of water for at least 15 minutes.
Use a mild soap if available to wash the skin gently.
If irritation or redness persists, seek medical attention.
Contaminated clothing should be removed and washed before reuse.


Eye Contact:

If Ethylenediaminetetraacetic acid disodium salt comes into contact with the eyes, rinse the affected eye(s) gently but thoroughly with lukewarm water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if there is no initial discomfort or redness.


Ingestion:

If Ethylenediaminetetraacetic acid disodium salt is ingested accidentally, do not induce vomiting unless directed to do so by medical professionals.
Rinse out the mouth with water if the substance has been swallowed.
Seek immediate medical attention or contact a poison control center.
Provide them with as much information as possible about the ingestion, including the amount ingested and the individual's weight.


General First Aid:

If any symptoms of exposure or irritation occur, such as difficulty breathing, skin irritation, eye irritation, or other discomfort, seek medical attention promptly.
Provide medical personnel with safety data sheets (SDS) or other relevant information about Ethylenediaminetetraacetic acid disodium salt for proper treatment guidance.
Keep contaminated clothing and personal protective equipment (PPE) separate from other items to avoid further contamination.



HANDLING AND STORAGE


Handling:

Personal Protective Equipment (PPE):
When working with Ethylenediaminetetraacetic acid disodium salt, wear appropriate personal protective equipment, including safety goggles or a face shield, chemical-resistant gloves, and a lab coat or protective clothing.

Ventilation:
Use adequate ventilation systems, such as fume hoods or local exhaust, to minimize exposure to airborne particles and dust.

Avoid Inhalation:
Avoid breathing in dust, vapors, or aerosols.
Use respiratory protection (e.g., N95 respirators) if working with fine powders or in poorly ventilated areas.

Prevent Skin and Eye Contact:
Prevent skin and eye contact by wearing suitable protective gear.
In case of accidental contact, follow first aid procedures.

Use Caution with Open Flames:
Do not use open flames, as Ethylenediaminetetraacetic acid disodium salt may produce hazardous fumes or gases when heated.

Avoid Eating, Drinking, or Smoking:
Do not eat, drink, or smoke in areas where Ethylenediaminetetraacetic acid disodium salt is handled.
Wash hands thoroughly after handling, especially before eating or drinking.


Storage:

Container:
Store Ethylenediaminetetraacetic acid disodium salt in well-sealed, labeled containers that are specifically designed for chemical storage.
Containers should be made of compatible materials, such as glass or plastic.

Temperature:
Store the chemical in a cool, dry place, away from direct sunlight, heat sources, and temperature extremes.

Moisture Control:
Protect the substance from moisture by keeping the containers tightly closed.
Consider using desiccants to maintain a low-humidity environment.

Isolation:
Store Ethylenediaminetetraacetic acid disodium salt away from incompatible materials, such as strong acids, strong bases, and reactive metals, to prevent reactions.

Childproofing:
Keep the chemical out of reach of children and unauthorized personnel.

Fire Safety:
Store away from open flames, sparks, or sources of ignition.

Labeling:
Ensure that containers are clearly labeled with the product name, hazard warnings, and handling instructions.

Segregation:
Store Ethylenediaminetetraacetic acid disodium salt separately from food, beverages, and personal items to prevent contamination.

Shelf Life:
Be aware of the product's shelf life and adhere to expiration dates.
Dispose of expired or degraded material properly.

Spill Containment:
Have appropriate spill containment measures and cleanup materials readily available in case of accidental spills or leaks.



SYNONYMS


Disodium EDTA
Sodium EDTA
Edetate disodium
Ethylenediaminetetraacetate disodium salt
Edathamil disodium
Disodium ethylene-diamine-tetraacetate
Edetic acid disodium salt
Disodium salt of EDTA
Sodium ethylenediaminetetraacetate
Disodium edetate
Sodium ethylenediaminetetraacetate dihydrate
EDTA Na2
Edetic acid sodium salt
Ethylenediaminetetraacetic acid disodium salt dihydrate
Sequestrene sodium
Titriplex II
Versene disodium
Edathamil disodium salt
Edetic acid disodium
Ethylenediaminetetraacetic acid sodium salt
Disodium ethylenediaminetetraacetate dihydrate
Sequestrene Na2
Tetrasodium EDTA
Titriplex III
Versene disodium salt
Edathamil disodium salt
Sodium edetate
Sodium ethylenediaminetetraacetate
Disodium ethylenediaminetetraacetate
Edetic acid sodium salt
Sodium diethylenetriaminepentaacetate
Edetate sodium
Disodium ethylene diamine tetraacetate
Edetate disodium salt
Sodium ethylenediaminetetracetate
Disodium edathamil
Disodium ethylenediaminetetraacetate dihydrate
Sodium EDTA dihydrate
Disodium versenate
Sodium versenate
Diethylenetriamine pentaacetate disodium salt
Disodium diethylenetriaminepentaacetate
Tetrasodium ethylenediaminetetraacetate
Disodium ethylenediaminetetraacetate dihydrate
Sodium diethylenetriamine pentaacetate
Ethylenediaminetetraacetate disodium salt hydrate
Diethylenetriaminepentaacetate disodium
Sodium edetate dihydrate
Disodium ethylenediamine tetraacetate
Edetate disodium dihydrate
EDTA Na2
Ethylenebis(iminodiacetic acid) disodium salt
Ethylenediamine-N,N,N',N'-tetraacetic acid disodium salt
Disodium ethylenediamine-N,N,N',N'-tetraacetate
Edathamil disodium
Sodium ethylenediaminetetraacetate dihydrate
Diethylenetriamine pentaacetic acid disodium salt
Disodium edetate dihydrate
Sodium diethylenetriamine pentaacetate dihydrate
Disodium diethylenetriaminepentaacetate
Ethylenediaminetetraacetate sodium salt dihydrate
Disodium ethylenediaminetetraacetic acid dihydrate
Ethylenediaminetetraacetic acid disodium salt dihydrate
Disodium versenate dihydrate
Sodium versenate dihydrate
Diethylenetriaminepentaacetate disodium salt dihydrate
Sodium ethylenediaminetetraacetate dihydrate
Edetic acid disodium salt dihydrate
Diethylenetriamine pentaacetic acid sodium salt
Disodium diethylenetriaminepentaacetate dihydrate
Ethylenediaminetetraacetic acid disodium salt hydrate
Disodium ethylenediaminetetraacetate dihydrate hydrate
Sodium diethylenetriamine pentaacetate dihydrate hydrate
Edetate disodium dihydrate hydrate
Ethylenebis(iminodiacetic acid) disodium salt dihydrate

Ethylenediaminetetraacetic Acid Disodium Salt is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Ethylenediaminetetraacetic Acid Disodium Salt occurs as a white crystalline, odorless powder with a slightly acidic taste.


CAS Number: 6381-92-6/139-33-3
EC Number: 205-358-3
MDL Number: MFCD00070672
Molecular Formula: C10H14N2Na2O8


Ethylenediaminetetraacetic Acid Disodium Salt is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.
Ethylenediaminetetraacetic Acid Disodium Salt is a 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic Acid Disodium Salt is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 1 000 to < 10 000 tonnes per annum.


Ethylenediaminetetraacetic Acid Disodium Salts are more stable than edetic acid.
However, Ethylenediaminetetraacetic Acid Disodium Salt loses water of crystallization when heated to 120°C.
Aqueous solutions of disodium edetate may be sterilized by autoclaving, and should be stored in an alkali-free container.
Ethylenediaminetetraacetic Acid Disodium Salt is hygroscopic and is unstable when exposed to moisture.


Ethylenediaminetetraacetic Acid Disodium Salt should be stored in a well-closed container in a cool, dry place.
Ethylenediaminetetraacetic Acid Disodium Salt is the disodium salt form of edetate, a heavy metal chelating agent.
Ethylenediaminetetraacetic Acid Disodium Salt, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes.
Ethylenediaminetetraacetic Acid Disodium Salt inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt, dihydrate is a chelating agent for metal ions in aqueous solution like Fe3+, Co2+, Fe2+, Mn2+, Ca2+, and Mg2+.
Ethylenediaminetetraacetic Acid Disodium Salt is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels.


Ethylenediaminetetraacetic Acid Disodium Salt is a 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic Acid Disodium Salt's function is comparable to that of disodium calcium edta.
Ethylenediaminetetraacetic Acid Disodium Salt is an organic sodium salt that is the anhydrous form of the disodium salt of ethylenediaminetetraacetic acid (EDTA).


Ethylenediaminetetraacetic Acid Disodium Salt has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Ethylenediaminetetraacetic Acid Disodium Salt is an aminopolycarboxylic acid and a hexadentate ligand.
Ethylenediaminetetraacetic Acid Disodium Salt chelates with metal ions, especially with cations to form an octahedral complex.


Ethylenediaminetetraacetic Acid Disodium Salt is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Ethylenediaminetetraacetic Acid Disodium Saltis produced as several salts, e.g. ethylenediaminetetra-acetic acid disodium salt (EDTAS).
Ethylenediaminetetraacetic Acid Disodium Salt is soluble in Aqueous Base (Slightly), Water (Sparingly, Sonicated).



USES and APPLICATIONS of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt is a sterile chelating reagent.
Ethylenediaminetetraacetic Acid Disodium Salt is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: washing & cleaning products, coating products, adhesives and sealants, biocides (e.g. disinfectants, pest control products), fillers, putties, plasters, modelling clay, polishes and waxes, non-metal-surface treatment products, metal surface treatment products, air care products, textile treatment products and dyes and photo-chemicals.


Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials), indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters), outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and industrial abrasion processing with high release rate (e.g. sanding operations or paint stripping by shot-blasting).


Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment), indoor use in long-life materials with high release rate (e.g. release from fabrics, textiles during washing, removal of indoor paints), outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).


Ethylenediaminetetraacetic Acid Disodium Salt can be found in complex articles, with no release intended: vehicles, machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines) and electrical batteries and accumulators.


Ethylenediaminetetraacetic Acid Disodium Salt can be found in products with material based on: stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), leather (e.g. gloves, shoes, purses, furniture), metal (e.g. cutlery, pots, toys, jewellery), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), wood (e.g. floors, furniture, toys) and plastic (e.g. food packaging and storage, toys, mobile phones).


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: laboratory chemicals.
Ethylenediaminetetraacetic Acid Disodium Salt is used in the following areas: formulation of mixtures and/or re-packaging and mining.
Ethylenediaminetetraacetic Acid Disodium Salt is used for the manufacture of: chemicals.


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: in processing aids at industrial sites, in the production of articles, as processing aid and of substances in closed systems with minimal release.
Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Ethylenediaminetetraacetic Acid Disodium Salt is used in the following products: laboratory chemicals and cosmetics and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt has an industrial use resulting in manufacture of another substance (use of intermediates).
Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: formulation of mixtures and formulation in materials.
Ethylenediaminetetraacetic Acid Disodium Salt is used in the following areas: mining and building & construction work.


Ethylenediaminetetraacetic Acid Disodium Salt is used for the manufacture of: chemicals and mineral products (e.g. plasters, cement).
Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: as processing aid, in processing aids at industrial sites, in the production of articles and of substances in closed systems with minimal release.


Other release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).


Release to the environment of Ethylenediaminetetraacetic Acid Disodium Salt can occur from industrial use: manufacturing of the substance, formulation of mixtures and as an intermediate step in further manufacturing of another substance (use of intermediates).
Ethylenediaminetetraacetic Acid Disodium Salt also acts as a food additive.


Ethylenediaminetetraacetic Acid Disodium Salt is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic Acid Disodium Salt's function is comparable to that of disodium calcium edta.


Disodium Dihydrogen Ethylenediaminetetraacetate Solution is generally immediately available in most volumes.
High purity, submicron and nanopowder forms may be considered.
American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.


Ethylenediaminetetraacetic Acid Disodium Salt is used in detergents, liquid soap, shampoo, agricultural chemicals, fixer solution for development of color film, water cleaner, pH modifier.
When stating the redox reaction for the polymerization of butyl benzene rubber, Ethylenediaminetetraacetic Acid Disodium Salt is used as part of activator for the control of polymerization speed.


Ethylenediaminetetraacetic Acid Disodium Salt is widely used in textile industry.
Usually Ethylenediaminetetraacetic Acid Disodium Salt is applied to dissolve limescale.
Ethylenediaminetetraacetic Acid Disodium Salt is applied in textile industry, pulp and paper industry and also in chelation therapy.


In cosmetics, Ethylenediaminetetraacetic Acid Disodium Salt acts as a sequestering agent.
Ethylenediaminetetraacetic Acid Disodium Salt acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a preservative used in concentrations of 0.1 to 0.5 percent.
Ethylenediaminetetraacetic Acid Disodium Salt is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.


Ethylenediaminetetraacetic Acid Disodium Salt is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic Acid Disodium Salt is widely used in textile industry.
Usually applied to dissolve limescale.


Ethylenediaminetetraacetic Acid Disodium Salt has a wide range of coordination properties, and can form stable chelates with almost all metal ions.
Ethylenediaminetetraacetic Acid Disodium Salt provides the possibility to determine elements widely (better than acid-base and precipitation methods).
Ethylenediaminetetraacetic Acid Disodium Salt chelating agents are widely used in water treatment, dyeing, oil cleaning, etc.


Ethylenediaminetetraacetic Acid Disodium Salt is used as a
biological buffer, Chelation/Complexation reagent.
Ethylenediaminetetraacetic Acid Disodium Salt is used widely in topical, oral, and parenteral pharmaceutical formulations; it is used extensively in cosmetic and food products.


Ethylenediaminetetraacetic Acid Disodium Salt is used in a greater number and variety of pharmaceutical formulations than edetic acid.
Ethylenediaminetetraacetic Acid Disodium Salt is poorly absorbed from the gastrointestinal tract and is associated with few adverse effects when used as excipients in pharmaceutical formulations.


Ethylenediaminetetraacetic Acid Disodium Salt is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Ethylenediaminetetraacetic Acid Disodium Salt is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.


Ethylenediaminetetraacetic Acid Disodium Salt is used as chelating agent for metals and as pharmaceutic aid (chelating agent).
Ethylenediaminetetraacetic Acid Disodium Salt is used as preservative in cosmetic products.
Ethylenediaminetetraacetic Acid Disodium Salt is also used as anticoagulant.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelating agent (metal); pharmaceutic aid (chelating agent).


Ethylenediaminetetraacetic Acid Disodium Salt is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Ethylenediaminetetraacetic Acid Disodium Salt acts as a sequestering agent.
Ethylenediaminetetraacetic Acid Disodium Salt acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt also acts as a food additive.


Ethylenediaminetetraacetic Acid Disodium Salt has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelator of divalent cations.
Ethylenediaminetetraacetic Acid Disodium Salt inhibits enzymes, such as metalloproteases, that require divalent cations for activity.


Ethylenediaminetetraacetic Acid Disodium Salt uses and applications include: Chelating agent in cosmetics, pharmaceuticals, water treatment, textiles, soapsdetergents, electroless copper plating, polymer production, disinfectants, pulppaper, enhanced oil recovery, metal cleaningprotection; scale inhibitor (boiler water treatment); textileleather processing auxiliaries; antioxidant for cosmetics; prevents metal-catalyzed oxidative breakdown; preservative, preservative synergist, antioxidant, stabilizer, chelant, sequestrant in foods; hog scald agent; anticoagulant; pharmaceutic aid; viscous control agent; chelating agent in food-contact paperpaperboard manufacturing; in cellophane for food packaging; chelating agentsequestrant in lubricants for incidental food-contact use; in food packaging adhesives; in surfactant lubricants for manufacturing of food-contact metallic articles.


Ethylenediaminetetraacetic Acid Disodium Salt is widely used as a chelating agent in a variety of pharmaceutical preparations, including mouthwashs, ophthalmic preparations and topical preparations.
Ethylenediaminetetraacetic Acid Disodium Salt is also used as a stabilizer for various emulsions.
Ethylenediaminetetraacetic Acid Disodium Salt is used in several industrial applications attributing to its high ability to bind to most of metal cations.


Ethylenediaminetetraacetic Acid Disodium Salt is used as chelating agents in cosmetic formulations.
EDTAS is a preservative, sequestrant, and stabilizer in foods.
EDTA is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
EDTA and its salts are used as a component in the production of food-contact paper and paperboard.


EDTAS is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, EDTA and its salts prevent metal ion impurities from changing colors of dyed products.
In the pulp and paper industry, EDTA and its salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).


EDTA is used in synthetic rubber manufacture.
EDTA is also used as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic Acid Disodium Salt chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Ethylenediaminetetraacetic Acid Disodium Salt enhances the antibacterial activity of lysozyme.


Ethylenediaminetetraacetic Acid Disodium Salt is used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Ethylenediaminetetraacetic Acid Disodium Salt chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.


Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt is used as a stabilizer for various emulsions.


Ethylenediaminetetraacetic Acid Disodium Salt is added to foods and personal care products.
Ethylenediaminetetraacetic Acid Disodium Salt is used in aqueous solutions with other reagents and inert materials for the preparation of cleaning mixtures and poultices to be applied to stone surfaces and frescoes.


Ethylenediaminetetraacetic Acid Disodium Salt, for its property of complexing calcium within crusts and for its good solubility (better than tetrasodium salt), is used in the AB 57 poultice (I.C.R. formulation - Rome).
Ethylenediaminetetraacetic Acid Disodium Salt is besides a strong chelating agent of a great many metallic cations, as iron and copper; this property can be utilized to remove stains of rust or copper green from stone surfaces, wood, plasters, etc…


-Personal care & skincare products:
Binding to free metal ions and serves as a purifying agent and preservative.
-Shampoos and soaps:
Reducing the "hardness" (or presence of metal cations) in tap water so that other ingredients can work to cleanse more efficiently.


-Laundry detergents:
To soften water that comes into contact with it so the other active ingredients can cleanse better.
-Textiles:
Preventing the discolouring of dyed fabrics by removing harmful free metal ions and getting rid of residue left on industrial equipment.


-Agriculture Fertilizers:
Ethylenediaminetetraacetic Acid Disodium Salt is mainly used as foliar fertilizers, water-soluble fertilizers to supply trace elements for vegetables, crops, and fruits.
-Foods:
Ethylenediaminetetraacetic Acid Disodium Salt is used for chelating metal ions, removing heavy metals of foods.
EDTA metal salts e.g. Ca, Zn, Fe, are used for supplying micronutrients for human.


-Cosmetic Uses of Ethylenediaminetetraacetic Acid Disodium Salt:
*chelating agents
*viscosity controlling agents


-Biochem/physiol Actions of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Ethylenediaminetetraacetic Acid Disodium Salt is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.


-Pharmaceutical Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Ethylenediaminetetraacetic Acid Disodium Salt forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form of Ethylenediaminetetraacetic Acid Disodium Salt has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.


-Veterinary Drugs and Treatments:
Ethylenediaminetetraacetic Acid Disodium Salt is a chelating agent that is also used to stop the melting effect of collagenases and proteases on the cornea.
Ethylenediaminetetraacetic Acid Disodium Salt is useful in halting melting through inhibition of matrix metalloproteinases, but is not felt to be useful for melting caused by infectious agents.
As the effect of Ethylenediaminetetraacetic Acid Disodium Salt on metalloproteinases is reversible, it must be administered several times daily to be effective.


-Industrial Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Ethylenediaminetetraacetic Acid Disodium Salt is also used in redox reaction for the polymerization of butyl benzene rubber.
Ethylenediaminetetraacetic Acid Disodium Salt is used as part of activator for the control of polymerization speed.


-Personal Care Applications of Ethylenediaminetetraacetic Acid Disodium Salt:
Ethylenediaminetetraacetic Acid Disodium Salt is used in Cosmetics to increase effectiveness and improve stability of bar and solid soaps, bath preparations; creams, oils, hair care products and many other personal care formulations.
-Application of Ethylenediaminetetraacetic Acid Disodium Salt:
*Surfactants & Emulsifiers



FUNCTIONS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
*Preservative
*Scale Inhibitor
*Stabilizer
*Lubricant



INDUSTRY:
*Cosmetic
*Plating
*Pharmaceutical
*Water Treatment
*Textiles
*Adhesives
*Detergent



INCOMPATIBILITIES OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt behaves as a weak acid, displacing carbon dioxide from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic Acid Disodium Salt is incompatible with strong oxidizing agents, strong bases, metal ions, and metal alloys.



MANUFACTURING PROCESS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.

Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.
This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.

Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.
About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.

To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.
The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.

A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic Acid Disodium Salt is a white crystalline solid.



PRODUCTION METHODS OF ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Ethylenediaminetetraacetic Acid Disodium Salt may be prepared by the reaction of edetic acid and sodium hydroxide.



PHYSICAL and CHEMICAL PROPERTIES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
Formula: [CH2N(CH2COOH)CH2COONa]2·2H2O
Appearance: white crystals
Assay: 99% min.
Specific gravity: 0.8 - 1.1 kg/l at 20°C
pH: 4,5-5 in 10% aqueous solution
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in: water, 1e+006 mg/L @ 25 °C (est)
Insoluble in: alcohol
Form: powder
Colour: white
Odour: product specific
Odour threshold:
not determined
pH value: 4 - 5 (DIN 19268)
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C

vapor pressure: 0Pa at 25℃
storage temp.: 2-8°C
solubility: H2O: clear, colorless
form: solution
color: ≤5 (0.5 M)(APHA)
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
Self ignition: not self-igniting
Test type: Spontaneous selfignition at room-temperature.
Temperature: > 400 °C Test type: Self-ignition at high
Pressure: 1.013,25 hPa temperatures.
No self ignition was observed up to (Method: Regulation
the specified temperature. 440/2008/EC, A.16)
Viscosity, dynamic:
Study scientifically not justified.
Viscosity, kinematic: not applicable, the product is a solid

Explosion hazard: Product is not explosive, however a dust explosion could result from an air / dust mixture.
Fire promoting properties: Based on its structural properties the product is not classified as oxidizing.
Other information:
Self heating ability: It is not a substance capable of spontaneous heating.
Minimum ignition energy: > 4 J (DIN EN 13821) (1.013,25 hPa, 20 °C)
Bulk density: approx. 950 kg/m3 (DIN ISO 697)
Surface tension: Based on chemical structure, surface activity is not to be expected.
Grain size distribution: particles < 100 µm approx. 29 %
particles < 10 µm approx. 1,2 %
particles < 4 µm approx. 0,2 %
Melting Point: >250°C (dec.)
Density: 1.01 g/mL at 25°C
InChI Key: ZGTMUACCHSMWAC-UHFFFAOYSA-L
Stability: Stable.
Molecular Formula: C₁₀H₁₄N₂Na₂O₈
Appearance: White to Off-White Solid
Melting Point: >250°C (dec.)
Molecular Weight: 336.21
Storage: 4°C, Hygroscopic
Solubility: Aqueous Base (Slightly), Water (Sparingly, Sonicated)
Stability: Hygroscopic



FIRST AID MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Description of first aid measures:
Remove contaminated clothing.
*If inhaled:
Keep patient calm, remove to fresh air, seek medical attention.
*On skin contact:
Wash thoroughly with soap and water.
*On contact with eyes:
Wash affected eyes for at least 15 minutes under running water with eyelids held open.
*On ingestion:
Immediately rinse mouth and then drink 200-300 ml of water, seek medical attention.
-Indication of any immediate medical attention and special treatment needed:
*Treatment:
Treat according to symptoms, with no known specific antidote.



ACCIDENTAL RELEASE MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Personal precautions, protective equipment and emergency procedures:
Use personal protective clothing.
-Environmental precautions:
Contain contaminated water/firefighting water.
Do not discharge into drains/surface waters/groundwater.
-Methods and material for containment and cleaning up:
*For small amounts:
Pick up with suitable appliance and dispose of.
*For large amounts:
Contain with dust binding material and dispose of.
Dispose of absorbed material in accordance with regulations.



FIRE FIGHTING MEASURES of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Extinguishing media:
*Suitable extinguishing media:
dry powder, foam
-Advice for fire-fighters:
*Further information:
Contaminated extinguishing water must be disposed of in accordance with official regulations.



EXPOSURE CONTROLS/PERSONAL PROTECTION of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Exposure controls:
--Personal protective equipment:
*Hand protection:
Chemical resistant protective gloves.
*Supplementary note:
Manufacturer's directions for use should be observed because of great diversity of types.
*Eye protection:
Safety glasses with side-shields (frame goggles)
-General safety and hygiene measures:
Wearing of closed work clothing is recommended.
No eating, drinking, smoking or tobacco use at the place of work.
Handle in accordance with good industrial hygiene and safety practice.



HANDLING and STORAGE of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Conditions for safe storage, including any incompatibilities:
*Suitable materials for containers:
Low density polyethylene (LDPE), glass, Paper/Fibreboard, High density polyethylene (HDPE)
-Further information on storage conditions:
Keep container tightly closed and dry; store in a cool place.



STABILITY and REACTIVITY of ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT:
-Reactivity:
No hazardous reactions if stored and handled as prescribed/indicated.
*Corrosion to metals:
No corrosive effect on metal.
-Chemical stability:
The product is stable if stored and handled as prescribed/indicated.



SYNONYMS:
Disodium EDTA
Isodium dihydrogen ethylenediaminetetraacetate
Edetic acid disodium salt
EDTA disodium salt
(Ethylenedinitrilo)tetraacetic acid disodium salt
Disodium Edetate
Chelaplex
Chelaplex III
Chelaton III
Chelest 200
Chelest 2B-SD
Chelest 2BS
Chelest B; Clewat N
Clewat N 2
Complexon III
Disodium (Ethylenedinitrilo)tetraacetate
Disodium EDTA
Disodium Diacid Ethylenediaminetetraacetate
Disodium Dihydrogen Ethylenediaminetetraacetate
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT
1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID DISODIUM SALT 2H2O
4C EDTA
COMPLEXONE III
COMPLEXONE III(R)
DISODIUM DIHYDROGEN ETHYLENEDIAMINE TETRAACETATE
DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRAACETATE DIHYDRATE
DISODIUM DIHYDROGEN ETHYLENEDIAMINETETRA-ACETIC DIHYDRATE
DISODIUM EDETATE
DISODIUM EDETATE DIHYDRATE
DISODIUM EDTA
DISODIUM ETHYLENEDIAMINETETRAACETATE
DISODIUM ETHYLENEDIAMINETETRAACETATE DIHYDRATE
Disodium ethylenediaminetetraacetic acid
DISODIUM (ETHYLENEDINITRILO)TETRAACETATE, DIHYDRATE
EDATHAMIL DISODIUM SALT DIHYDRATE
EDETATE DISODIUM
EDETATE DISODIUM, DIHYDRATE
EDETATE DISODIUM DIHYDROGEN, DIHYDRATE
EDETATE DISODIUM SALT DIHYDRATE
(Ethylenedinitrilo)tetraacetic acid disodium salt
EDTA disodium salt, EDTA-Na2
(Ethylenedinitrilo)tetraacetic Acid Disodium Salt
EDTA Disodium Salt; EDTA-Na2
Ethylenediamine-N,N,N',N'-tetraacetic Acid Disodium Salt
EDNRA
1,2-Diaminoethane-N,N,N',N'-tetra-acetic Acid Sisodium Salt
ETHYLENEBIS(IMINODIACETIC ACID)DISODIUM SALT
ETHYLENEDIAMINETETRAACETIC ACID, 2NA, DIHYDRATE
ETHYLENE DIAMINETETRA ACETIC ACID DISODIUM
ETHYLENEDIAMINE TETRAACETIC ACID DISODIUM DIHYDRATE
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT-2-HYDRATE
ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID DISODIUM SALT
ETHYLENEDIAMINETETRAACETATE DISODIUM SALT
(ETHYLENENDINITRILO)TETRAACETIC ACID, DISODIUM SALT, DIHYDRATE
(ETHYLENEDINITRILO)TETRAACETIC DISODIUM, DIHYDRATE
Disodium EDTA
Disodium dihydrogen ethylenediaminetetraacetate
Disodium edetate
Disodium ethylenediamine tetraacetate
Edetate disodium
Ethylenediaminetetraacetic acid, disodium salt (Ethylenedinitrilo) tetraacetic acid, sodium salt
Glycine, N,N-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt dihydrate
Chelaplex
Chelaplex III
Chelaton III
Chelest B
Disodium (Ethylenedinitrilo)tetraacetate
Disodium EDTA
Disodium Diacid Ethylenediaminetetraacetate
Disodium Dihydrogen Ethylenediaminetetraacetate
Disodium Edathamil
Disodium Edetate
Disodium Ethylenediamine-N,N,N',N'-tetraacetate
Disodium Ethylenediaminetetraacetate
Disodium Ethylenediaminetetraacetic Acid Salt
Disodium Sequestrene
Disodium Tetracemate
Disodium Versenate
Disodium Versene
EDTA Disodium Salt
Edathamil Disodium
Edetate Disodium
Endrate Disodium
Ethylenedinitrilotetraacetate Disodium
EDTA-2NA
DISODIUM EDTA
DISODIUM EDETATE
ETA;EDETATE DISODIUM
EDTA DISODIUM
EDTA DISODIUM SALT
TITRIPLEX III
DISODIUM ETHYLENEDIAMINETETRAACETATE
EDTA NA2
Ethylenediaminetetra-acetic acid disodium salt dihydrate
Edetate disodium dihydrate
Ethylenediaminetetraacetic acid, disodium salt, dihydrate
Kestranal 2S 2 H2O
Ethylenedinitrilotetra-acetic acid disodium salt dihydrate
Titriplex III
Kestranal 2S dihydrate
Edetic acid disodium salt dihydrate
Disodium dihydrogen ethylenediaminetetraacetate dihydrate

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in several industrial applications attributing to its high ability to bind to most of metal cations.
EDTA is produced as several salts, e.g. Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts are used as chelating agents in cosmetic formulations.

CAS: 139-33-3
MF: C10H14N2Na2O8
MW: 336.21
EINECS: 205-358-3

Synonyms
SEQUESTRENE NA2;SODIUM (DI) ETHYLENEDIAMINE TETRAACETATE DIHYDRATE;VERSENE NA, DIHYDRATE;VERSENE DISODIUM;WANKLYN'S EDTA;Ceftriaxone Impurity 21（EDTA Disodium）;disodium ethylenediamintetraacetate;EDTA two sodium;Edetate disodium;139-33-3;EDTA disodium salt;Disodium edetate;Edta disodium;Titriplex III;Disodium EDTA;Disodium edta,anhydrous;Cheladrate;Ethylenediaminetetraacetic acid disodium salt;Disodium versene;Endrate disodium;Sodium versenate;Disodium salt of EDTA;Metaquest B;Kiresuto B;Chelaplex III;Chelest B;Diso-Tate;Komplexon III;Chelaton III;Clewat N;Versene NA;Triplex III;Chelaton 3;Disodium versenate;Edathamil disodium;Trilon BD;Versene Na2;Zonon D;Edetate disodium anhydrous;Dotite 2NA;Selekton B 2;Disodium sequestrene;Disodium tetracemate;Mavacid ED 4;Versonol 120;Disodium ethylenediaminetetraacetate;Chelest 200;Sequestrene sodium 2;Veresene disodium salt;Disodium EDTA dihydrate;Perma Kleer Di Crystals;Edetic acid disodium salt;Glycine, N,N'-1,2-ethanediylbis[N-(carboxymethyl)-, disodium salt;Ethylenediaminetetraacetic acid, disodium salt;CCRIS 3658;E.D.T.A. disodique;EDTA-Na2;Disodium dihydrogen ethylenediaminetetraacetate;NSC 2760;EDTA disodium salt (anhydrous);Anhydrous disodium edetate;EINECS 205-358-3;Disodium ethylenediamine-N,N,N',N'-tetraacetate;Perma kleer 50 crystals disodium salt;UNII-8NLQ36F6MM;Disodium ethylenediaminetetraacetic acid;Edetate disodium, anhydrous;Ethylene diamine tetraacetic acid, disodium salt;Disodium (ethylenedinitrilo)tetraacetate;Edetic Acid, Disodium Salt;CBC 50152966
;DR-16133;Ethylenediaminetetraacetate, disodium salt;Disodium diacid ethylenediaminetetraacetate;MFCD00070672;AI3-18049;Disodium (ethylenedinitrilo)tetraacetic acid;Dinatrium ethylendiamintetraacetat;HSDB 8013;Trilon B;Disodium dihydrogen(ethylenedinitrilo)tetraacetate;Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, disodium salt;Endrate (TN);Disodium edathamil;6381-92-6;disodium 2-({2-[(carboxylatomethyl)(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate;Tetracemate disodium;Na2-EDTA
;N,N'-1,2-Ethanediylbis(N-(carboxymethyl)glycine) disodium salt;EC 205-358-3;Edta disodium salt anhydrous;8NLQ36F6MM;CHEBI:64734;Disodium N,N'-1,2-ethanediylbis(N-(carboxymethyl)glycine);ACETIC ACID, (ETHYLENEDINITRILO)TETRA-, DISODIUM SALT;NSC-2760;E.D.T.A. disodique [French];F 1 (VAN);ethylenediamine tetraacetic acid disodium salt;Dinatrium ethylendiamintetraacetat [Czech];Ethylenebis(iminodiacetic acid) disodium salt;disodium 2-((2-((carboxylatomethyl)(carboxymethyl)amino)ethyl(carboxymethyl)amino)acetate;(Ethylenedinitrilo)-tetraacetic acid disodium salt;Na2EDTA;0.5M Sodium EDTA;Disodium edetate (TN);Na2.EDTA;CHEMBL1749;DTXSID9027073;disodium ethylenediamine-tetraacetate;AKOS016370696;DB14600;SB40706;69772-70-9;E386;ethylenediaminetetracetic acid disodium salt;DB-042467;NS00078150;EN300-35828;ethylenediaminetetra-acetic acid disodium salt;D03945;P17519;J-007267;J-521348;Q4532977;disodium 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetate;Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, sodium salt (1:2);(Ethylenedinitrilo)tetraacetic acid disodium salt, EDTA disodium salt, EDTA-Na2;2-[2-(Carboxylatomethyl-(carboxymethyl)amino)ethyl-(carboxymethyl)amino]acetate disodium;disodium;2-[2-[carboxylatomethyl(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate;DISODIUM 2-({2-[(CARBOXYLATOMETHYL)(CARBOXYMETHYL)AMINO]ETHYL(CARBOXYMETHYL)AMINO)ACETATE

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a preservative, sequestrant, and stabilizer in foods.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is added to ascorbic acid-disodium benzoate containing soft drinks to mitigate the formation of benzene.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and its salts are used as a component in the production of food-contact paper and paperboard.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is permitted in the feed and drinking water of animals and/or for the treatment of food-producing animals.
In the textile industry, EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts prevent metal ion impurities from changing colors of dyed products.
In the pulp and paper industry, EDTA and Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s salts inhibit the ability of metal ions from catalyzing the disproportionation of hydrogen peroxide (a typical bleaching agent).
EDTAS is used in synthetic rubber manufacture.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used as a corrosion inhibitor to carbon steel in the industries.
As an anticoagulant, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and tripotassium salts of EDTA are most commonly used.
An organic sodium salt that is the anhydrous form of the disodium salt of Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a calcium ion chelator, that has a low molecular mass of 292.24 Da.
​Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a chelating agent, used to sequester and decrease the reactivity of metal ions that may be present in many industrial and personal care products.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), also called EDTA acid after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH2N(CH2CO2H)2]2.
This white, water-insoluble solid is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes even at neutral pH.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is thus used to dissolve Fe- and Ca-containing scale as well as to deliver iron ions under conditions where its oxides are insoluble.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is available as several salts, notably disodium EDTA, sodium calcium edetate, and tetrasodium EDTA, but these all function similarly.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) Chemical Properties
Melting point: 248 °C (dec.)(lit.)
Boiling point: >100 °C
Density: 1.01 g/mL at 25 °C
Vapor pressure: 0Pa at 25℃
Storage temp.: 2-8°C
Solubility H2O: clear, colorless
Form: solution
Color: ≤5 (0.5 M)(APHA)
Odor: at 100.00?%. odorless
Water Solubility: Miscible with water.
BRN: 3822669
Stability: Hygroscopic
LogP: -4.3 at 25℃
CAS DataBase Reference: 139-33-3(CAS DataBase Reference)
EPA Substance Registry System: Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) (139-33-3)
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) occurs as a white crystalline, odorless powder with a slightly acidic taste.

uses
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is an aminopolycarboxylic acid and a hexadentate ligand.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelates with metal ions, especially with cations to form an octahedral complex.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) enhances the antibacterial activity of lysozyme.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) chelation therapy may also protect from oxidative damage during blood and lipid peroxidation in liver fibrosis.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a preservative used in concentrations of 0.1 to 0.5 percent.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a sequestrant and chelating agent whose complete name is disodium ethylenediamine tetraacetate.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a nonhygroscopic powder that is colorless, odorless, and tasteless at recommended use levels. A 1% solution has a ph of 4.3–4.7.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used to control the reaction of trace metals to include calcium and magnesium with other organic and inorganic components in food to prevent deterioration of color, texture, and development of precipitates and to prevent oxidation.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na)'s function is comparable to that of disodium calcium edta.

Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is widely used in textile industry. Usually applied to dissolve limescale.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is applied in textile industry, pulp and paper industry and also in chelation therapy.
In cosmetics, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) acts as a sequestering agent.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) acts as a corrosion inhibitor to carbon steel in the industries.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) also acts as a food additive.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has been in seed germination trials of plant species and in protein extraction from Moss, Physcomitrella paten.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has also been used in lysis and vacuole buffer for the isolation of vacuoles from Petunia petals.

Pharmaceutical Applications
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used as a chelating agent in a wide range of pharmaceutical preparations, including mouthwashes, ophthalmic preparations, and topical preparations, typically at concentrations between 0.005 and 0.1% w/v.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) forms stable water-soluble complexes (chelates) with alkaline earth and heavy-metal ions.
The chelated form has few of the properties of the free ion, and for this reason chelating agents are often described as ‘removing’ ions from solution, a process known as sequestering.
The stability of the metal–edetate complex is dependent on the metal ion involved and the pH.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used as a water softener as it will chelate calcium and magnesium ions present in hard water.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used therapeutically as an anticoagulant as it will chelate calcium and prevent the coagulation of blood in vitro.
Concentrations of 0.1% w/v are used in small volumes for hematological testing and 0.3% w/v in transfusions.

Industrial Applications
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in cleaners, detergent, fertilizers, fixer solution for development of colour film, water cleaner and pH modifier.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is also used in redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed.

Uses
Textiles and paper
In industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly used to sequester (bind or confine) metal ions in aqueous solution.
In the textile industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) prevents metal ion impurities from modifying colours of dyed products.
In the pulp and paper industry, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) inhibits the ability of metal ions, especially Mn2+, from catalysing the disproportionation of hydrogen peroxide, which is used in chlorine-free bleaching.

Food
In a similar manner, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is added to some food as a preservative or stabiliser to prevent catalytic oxidative decolouration, which is catalysed by metal ions.

Water softener
The reduction of water hardness in laundry applications and the dissolution of scale in boilers both rely on Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) and related complexants to bind Ca2+, Mg2+, as well as other metal ions.
Once bound to Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), these metal complexes are less likely to form precipitates or to interfere with the action of the soaps and detergents.
For similar reasons, cleaning solutions often contain Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na).
In a similar manner Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is used in the cement industry for the determination of free lime and free magnesia in cement and clinkers.

The solubilisation of Fe3+ ions at or below near neutral pH can be accomplished using EDTA.
This property is useful in agriculture including hydroponics.
However, given the pH dependence of ligand formation, EDTA is not helpful for improving iron solubility in above neutral soils.
Otherwise, at near-neutral pH and above, iron(III) forms insoluble salts, which are less bioavailable to susceptible plant species.

Manufacturing Process
10 mols of ethylene diamine as a 30% aqueous solution and 4 mols of solid caustic soda are placed in a steam heated kettle supplied with an agitator.
8 mols of sodium cyanide as a concentrated water solution (about 30%) are added and the solution heated to 60°C.
About a 10 inch vacuum is applied to bring the liquid to incipient boiling.
Formaldehyde (7.5 mols of 37% to 40% aqueous solution) is slowly added, the temperature being held at 60°C, and the solution vigorously stirred.
Then, when the evolution of ammonia has substantially stopped, an additional 8 mols of sodium cyanide, followed by 8 mols of formaldehyde are added as before.
This is continued until 40 mols of cyanide and 40 mols of formaldehyde have been added.
Then at the end about 2 mols more of formaldehyde are added, making 42 mols in all, to remove any last traces of cyanide.

About 8 to 10 hours are required to complete the reaction.
The resulting product, referred to herein as the crude reaction product, is essentially an aqueous solution of the sodium salt of ethylene diamine tetracetic acid.
To 1,000 g of the crude reaction product are added 264 g of ethylene diamine tetracetic acid.
The mixture is preferably heated to incipient boiling to increase the rate of reaction, and then the mixture is allowed to cool and crystallize.
The crystals formed are filtered off, washed with the smallest possible amount of ice water, and dried to a constant weight, which is 452 g.
A representative sample of the product so prepared showed, upon analysis, 13.26% sodium against a theoretical of 13.70% for the disodium salt.
The dialkali salt has a pH of about 5.3 and behaves like a weak acid, displacing CO2 from carbonates and reacting with metals to form hydrogen.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a white crystalline solid.

Synthesis
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) was first described in 1935 by Ferdinand Münz, who prepared the compound from ethylenediamine and chloroacetic acid.
Today, Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly synthesised from ethylenediamine (1,2-diaminoethane), formaldehyde, and sodium cyanide.
This route yields the tetrasodium Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na), which is converted in a subsequent step into the acid forms:

H2NCH2CH2NH2 + 4 CH2O + 4 NaCN + 4 H2O → (NaO2CCH2)2NCH2CH2N(CH2CO2Na)2 + 4 NH3
(NaO2CCH2)2NCH2CH2N(CH2CO2Na)2 + 4 HCl → (HO2CCH2)2NCH2CH2N(CH2CO2H)2 + 4 NaCl
This process is used to produce about 80,000 tonnes of EDTA each year.
Impurities cogenerated by this route include glycine and nitrilotriacetic acid; they arise from reactions of the ammonia coproduct.

Biochem/physiol Actions
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has the ability to block the binding of vasoactive intestinal peptide to macrophage membranes.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is mainly used in the purification of protein, to remove divalent cations and also to prevent protease activity.

Side effects
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) exhibits low acute toxicity with LD50 (rat) of 2.0 g/kg to 2.2 g/kg.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) has been found to be both cytotoxic and weakly genotoxic in laboratory animals. Oral exposures have been noted to cause reproductive and developmental effects.
The same study also found that both dermal exposure to Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) in most cosmetic formulations and inhalation exposure to EDTA in aerosolised cosmetic formulations would produce exposure levels below those seen to be toxic in oral dosing studies.

Veterinary Drugs and Treatments
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is a chelating agent that is also used to stop the melting effect of collagenases and proteases on the cornea.
Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) is useful in halting melting through inhibition of matrix metalloproteinases, but is not felt to be useful for melting caused by infectious agents.
As the effect of Ethylenediaminetetraacetic acid disodium salt (EDTA - 2Na) on metalloproteinases is reversible, it must be administered several times daily to be effective.

1,2-Diaminoethane, 1,2-Ethanediamine; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin; Aethylenediamin; 1,2-diaminoaethan; 1,2-Diamino-ethaan; 1, 2-Diamino-Ethano; Dimethylenediamine; Ethyleendiamine; Ethylene-diamine; β-Aminoethylamine CAS NO:107-15-3

1,2-Diaminoethane, 1,2-Ethanediamine; 1,2-Ethylenediamine; 1,2-Diaminoethane; EDA; Ethane-1,2-diamine; Aethaldiamin; Aethylenediamin; 1,2-diaminoaethan; 1,2-Diamino-ethaan; 1, 2-Diamino-Ethano; Dimethylenediamine; Ethyleendiamine; Ethylene-diamine; β-Aminoethylamine CAS NO:107-15-3

pentasodium ethylenediamine tetramethylene phosphonate ;pentasodium trihydrogen, ethylenedinitrilotetrakis(methylphosphonate); phosphonic acid, (1,2-ethanediylbis(nitrilobis(methylene)))tetrakis-, pentasodium salt cas no : 7651-99-2

ETHYLHEXANOL, N° CAS : 104-76-7, Nom INCI : ETHYLHEXANOL, Nom chimique : 2-Ethylhexan-1-ol, N° EINECS/ELINCS : 203-234-3. Ses fonctions (INCI) : Agent parfumant : Utilisé pour le parfum et les matières premières aromatiques. Noms français : 2-ETHYL HEXANOL; 2-ETHYL-1-HEXANOL; 2-Ethylhexyl alcohol; Alcool 2-éthylhexylique; Ethyl -2 hexanol;ETHYL-2 HEXANOL-1 ETHYLHEXANOL; Éthyl-2 hexanol; Noms anglais :2-Ethylhexanol; Utilisation et sources d'émission; Solvant de colorants, solvant de résines

Ethylhexanoic Acid is a colorless to light yellow liquid with a pungent odor.
Furthermore, Ethylhexanoic Acid is commonly used in the production of various chemicals, including plasticizers and lubricants.
Ethylhexanoic Acid can be harmful if ingested or inhaled, and proper safety precautions should be taken when handling it.


CAS Number: 2396-84-1
EC Number: 205-743-6
Chemical formula: C8H16O2
Molar mass: 144.214 g·mol−1
Appearance: Colorless liquid



APPLICATIONS


Ethylhexanoic Acid is used as a chemical intermediate for many products.
Moreover, Ethylhexanoic Acid is used in alkyd resins.

Ethylhexanoic Acid is used in the mid-1980s as a wood preservative to replace chlorophenols.
Further, Ethylhexanoic Acid is used to make plasticizers, lubricants, detergents, flotation aids, corrosion inhibitors, and alkyd resins.

Ethylhexanoic Acid is also used as a co-solvent and defoamer in pesticides, as the active ingredient in the wood preservative Sinesto B (not used in the US), in paint dryers, heat stabilizers for PVC, and as a catalyst for polyurethane foaming, solvent extraction, and dye granulation.
What is more, Ethylhexanoic Acid is not found in any pesticide products registered in the US.


Industry uses of Ethylhexanoic Acid:

Anti-adhesive agents
Corrosion inhibitor
Corrosion inhibitors and anti-scaling agents
Intermediate
Intermediates
Lubricants and lubricant additives
Lubricating agent
Not Known or Reasonably Ascertainable
Other
Other (specify)
Paint additives and coating additives not described by other categories
Process regulators
Processing aids, not otherwise listed
Propellants and blowing agents
Solvent


Ethylhexanoic Acid is used in the production of plasticizers to improve the flexibility and durability of plastics.
Furthermore, Ethylhexanoic Acid is a building block in the production of coatings, such as resins and polyurethanes.

Ethylhexanoic Acid is used in metalworking fluids to cool and lubricate metalworking machines.
Moreover, Ethylhexanoic Acid is used in the production of lubricants to reduce friction and wear between two surfaces.
Ethylhexanoic Acid is a raw material in the production of pharmaceuticals, such as antibiotics and anti-inflammatory drugs.

Ethylhexanoic Acid is used in the production of various chemical intermediates for further processing.
Besides, Ethylhexanoic Acid is used in the production of heat stabilizers for PVC applications.

Ethylhexanoic Acid is used in the production of fuel additives to improve fuel efficiency and reduce emissions.
In addition, Ethylhexanoic Acid is used as a precursor in the synthesis of various catalysts to speed up chemical reactions.

Ethylhexanoic Acid is used as a solvent in the production of various chemicals and materials.
More to that, Ethylhexanoic Acid is used in the production of agrochemicals, such as herbicides, fungicides, and insecticides, to protect crops from pests and diseases.


Here are some additional applications of Ethylhexanoic Acid:

Paint driers:

Ethylhexanoic Acid is used as a paint drier, which accelerates the drying process of paints and varnishes.

Adhesives:

Ethylhexanoic Acid is used as a raw material in the production of various adhesives, such as pressure-sensitive adhesives and hot-melt adhesives.

Corrosion inhibitors:

Ethylhexanoic Acid is used as a component in the formulation of corrosion inhibitors, which protect metals from corrosion.

Resin additives:

Ethylhexanoic Acid is used as a resin additive in the production of polyester and alkyd resins, which find use in coatings, adhesives, and plastics.

Surfactants:

Ethylhexanoic Acid is used in the production of surfactants, which are used to modify the surface tension of liquids, thereby improving their wetting and spreading properties.

Fragrances:

Ethylhexanoic Acid is used as a fragrance ingredient in the production of perfumes and other scented products.

Textile auxiliaries:

Ethylhexanoic Acid is used in the production of textile auxiliaries, which are used to enhance the performance of textile products, such as dyes, finishes, and coatings.

Metal salts:

Ethylhexanoic Acid is used to produce metal salts, which find use in various applications, such as inks, pigments, and catalysts.

Rubber additives:

Ethylhexanoic Acid is used as a rubber additive in the production of synthetic rubbers, which find use in various products, such as tires, hoses, and seals.

Plasticizers:

Ethylhexanoic Acid is a key component in the production of phthalate-free plasticizers, which are used in the production of food packaging materials and medical devices.

Coatings:

Ethylhexanoic Acid is used as a reactant in the production of acrylic resins, which find use in the production of paints, coatings, and adhesives.

Metalworking fluids:

Ethylhexanoic Acid is a common component in metalworking fluids due to its excellent lubricity and cooling properties.

Lubricants:

Ethylhexanoic Acid is used as a metal deactivator in lubricants to prevent oxidation and improve their performance at high temperatures.

Pharmaceuticals:

Ethylhexanoic Acid is used as a chiral building block in the synthesis of various drugs, such as the anti-inflammatory drug Naproxen.

Chemical intermediates:

Ethylhexanoic Acid is used as a key intermediate in the synthesis of various chemicals, such as fragrances, flavors, and surfactants.

Heat stabilizers:

Ethylhexanoic Acid is used in the production of heat stabilizers for PVC applications to prevent degradation and extend the lifespan of the material.

Fuel additives:

Ethylhexanoic Acid is used as a component in the production of fuel additives, such as octane boosters, which improve the performance and efficiency of gasoline engines.

Catalysts:

Ethylhexanoic Acid is used as a precursor in the synthesis of various catalysts, such as tin and zinc carboxylates, which find use in various chemical reactions.

Solvents:

Ethylhexanoic Acid is used as a solvent in the production of various chemicals, such as resins, coatings, and adhesives.

Agrochemicals:

Ethylhexanoic Acid is used as a key component in the production of herbicides, fungicides, and insecticides to protect crops from pests and diseases.


Overall, Ethylhexanoic Acid is a versatile chemical that finds use in various applications across different industries, thanks to its unique properties and versatility.


Ethylhexanoic Acid is not commonly used in consumer products, as it is primarily an industrial chemical with a wide range of industrial applications.
However, Ethylhexanoic Acid may be used as a raw material in the production of certain consumer products, such as coatings, adhesives, and plastics.

Additionally, some niche applications, such as the use of Ethylhexanoic Acid as a component in certain fragrances, may have consumer uses.
Overall, the use of Ethylhexanoic Acid is more common in industrial and commercial settings rather than in consumer products.


Ethylhexanoic Acid has various industrial applications, such as:

Coolant in automotives
Synthetic lubricant
Wetting agent
Co-solvent
Drying of paints
Defoaming agent in pesticides


Ethylhexanoic Acid is used as a synthetic lubricant due to its ability to reduce friction and wear between moving parts.
Further to that, Ethylhexanoic Acid is commonly used as a drying agent in paints and coatings to accelerate the drying process and improve film formation.

As a coolant in automotive applications, Ethylhexanoic Acid helps dissipate heat and prevent engine damage from overheating.
Ethylhexanoic Acid is utilized as a defoaming agent in pesticides to reduce foam formation during application and improve effectiveness.

In metalworking, Ethylhexanoic Acid is used as a corrosion inhibitor to protect against rust and other forms of corrosion.
Ethylhexanoic Acid is used as a wetting agent to reduce the surface tension of liquids and improve their ability to spread and penetrate surfaces.



DESCRIPTION


Ethylhexanoic acid is the organic compound with the formula CH3(CH2)3CH(C2H5)CO2H.
Furthermore, Ethylhexanoic acid is a carboxylic acid that is widely used to prepare lipophilic metal derivatives that are soluble in nonpolar organic solvents.

Ethylhexanoic acid is a colorless viscous oil.
More to that, Ethylhexanoic acid is supplied as a racemic mixture.
2-Ethylhexanoic acid is a branched-chain fatty acid.

Ethylhexanoic Acid is a colorless liquid with a pungent odor.
Thus, Ethylhexanoic Acid is soluble in alcohol, acetone, and ether.

Ethylhexanoic Acid is a carboxylic acid with the chemical formula C8H16O2.
Moreover, Ethylhexanoic Acid is a colorless liquid with a rancid odor and is soluble in water, ethanol, and ether.
It is also known as 2-ethylhexanoic acid or 2-EHA.

Ethylhexanoic Acid is primarily used as a raw material for the production of various chemicals and materials such as synthetic lubricants, plasticizers, and coatings.
Further, Ethylhexanoic Acid also has applications in the pharmaceutical and food industries.

Ethylhexanoic acid is a natural product found in Vitis vinifera and Artemisia arborescens with data available.
What is more, Ethylhexanoic Acid is a colorless liquid with a pungent odor.
Ethylhexanoic Acid is a carboxylic acid that belongs to the family of fatty acids.

Ethylhexanoic Acid is soluble in water, alcohol, and ether.
Further to that, Ethylhexanoic Acid has a wide range of industrial applications.

Ethylhexanoic Acid is used as a synthetic lubricant and as a drying agent in paints.
In addition, Ethylhexanoic Acid is also used as a coolant in automotive applications and as a defoaming agent in pesticides.

Ethylhexanoic Acid is produced through the oxidation of octanol or via the hydroformylation of butadiene.
Moreover, Ethylhexanoic Acid is also found naturally in human sweat and in breast milk.



PROPERTIES


Molecular Weight: 144.21
XLogP3: 2.6
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Rotatable Bond Count: 5
Exact Mass: 144.115029749
Monoisotopic Mass: 144.115029749
Topological Polar Surface Area: 37.3 Ų
Heavy Atom Count: 10
Formal Charge: 0
Complexity: 99.4
Isotope Atom Count: 0
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Covalently-Bonded Unit Count: 1
Compound Is Canonicalized: Yes
Boiling point: 226 - 229 °C (1013 hPa)
Density: 0.91 g/cm3 (20 °C)
Explosion limit: 0.9 - 6.7 %(V)
Flash point: 114 °C
Ignition temperature: 310 °C
Melting Point: -59 °C
pH value: 3 (1.4 g/l, H₂O, 20 °C)
Vapor pressure: Solubility: 1.4 g/l



FIRST AID


Skin Contact:

If Ethylhexanoic Acid comes into contact with skin, immediately remove any contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes.
Seek medical attention if skin irritation, redness, or pain persists.


Eye Contact:

If Ethylhexanoic Acid comes into contact with eyes, flush the affected eye with water for at least 15 minutes, lifting the upper and lower eyelids occasionally.
Seek medical attention immediately.


Inhalation:

If Ethylhexanoic Acid is inhaled, remove the affected person to fresh air immediately.
If the person is not breathing, administer artificial respiration.
Seek medical attention if the person experiences difficulty breathing, coughing, or wheezing.


Ingestion:

If Ethylhexanoic Acid is ingested, do not induce vomiting.
Rinse the mouth with water and drink plenty of water to dilute the acid.
Seek medical attention immediately.


Personal Protective Equipment:

Always wear personal protective equipment when handling Ethylhexanoic Acid, including gloves, goggles, and a lab coat or protective clothing.


Spill Response:

In the event of a spill, isolate the area and keep unauthorized personnel away.
Wear personal protective equipment and contain the spill with an absorbent material.
Collect the contaminated material and dispose of it according to local regulations.


It is important to note that Ethylhexanoic Acid can cause severe skin and eye irritation, and may be harmful if inhaled or ingested.
Seek immediate medical attention if exposure occurs.



HANDLING AND STORAGE


Ethylhexanoic Acid should be stored in a cool, dry, well-ventilated area, away from direct sunlight and sources of heat or ignition.
Further, Ethylhexanoic Acid should be kept in a tightly sealed container and handled only in a fume hood or with appropriate personal protective equipment.
Ethylhexanoic Acid should be stored separately from incompatible materials such as strong oxidizers, acids, and bases.

Containers of Ethylhexanoic Acid should be labeled with the appropriate hazard warnings and handling instructions.
When handling Ethylhexanoic Acid, appropriate personal protective equipment should be worn, including gloves, safety goggles, and a lab coat or apron.

In case of skin or eye contact, immediately flush the affected area with plenty of water for at least 15 minutes and seek medical attention.
If Ethylhexanoic Acid is ingested, do not induce vomiting and seek medical attention immediately.

Spills of Ethylhexanoic Acid should be cleaned up immediately using absorbent materials and appropriate protective equipment.
Disposal of Ethylhexanoic Acid should be done in accordance with local, state, and federal regulations, and should not be disposed of in regular trash or down the drain.

Ethylhexanoic Acid should be kept away from children and unauthorized personnel, and should only be handled by trained professionals who are familiar with the hazards and proper handling procedures.



SYNONYMS


2-ETHYLHEXANOIC ACID
149-57-5
2-Ethylcaproic acid
Hexanoic acid, 2-ethyl-
Ethylhexanoic acid
Ethylhexoic acid
2-Ethylhexoic acid
Butylethylacetic acid
2-Butylbutanoic acid
3-Heptanecarboxylic acid
Ethyl hexanoic acid
2-ethyl-hexoic acid
2-ethyl hexanoic acid
alpha-Ethylcaproic acid
2-ethyl-hexanoic acid
Ethyl hexanoic acid, 2-
2 ETHYL HEXANOIC ACID
alpha-ethyl caproic acid
.alpha.-Ethylcaproic acid
2-Ethyl-1-hexanoic acid
(+/-)-2-ETHYLHEXANOIC ACID
01MU2J7VVZ
2-ETHYL HEXOIC ACID,AR
61788-37-2
CHEBI:89058
NSC-8881
2-ethylhexanoicacid
2-Ethylhexansaeure
2-Ethylhexanoic acid, >=99%
2-Ethylhexanoic acid, analytical standard
CAS-149-57-5
CCRIS 3348
HSDB 5649
Kyselina 2-ethylkapronova [Czech]
NSC 8881
Kyselina 2-ethylkapronova
EINECS 205-743-6
UNII-01MU2J7VVZ
Kyselina heptan-3-karboxylova [Czech]
BRN 1750468
Kyselina heptan-3-karboxylova
AI3-01371
Hexanoic acid, 2-ethyl-, (-)-
EINECS 262-971-9
MFCD00002675
2-Ethylcapronic acid
2-Ethyl-Hexonic acid
alpha-Ethylhexanoic acid
.alpha.-Ethylhexanoic acid
EC 205-743-6
SCHEMBL25800
2-Ethylhexanoic acid, 99%
MLS002415695
CHEMBL1162485
DTXSID9025293
WLN: QVY4 & 2
NSC8881
HMS2267F21
STR05759
2-ETHYLHEXANOIC ACID [HSDB]
Tox21_201406
Tox21_300108
LMFA01020087
AKOS009031416
AT29893
CS-W016381
SB44987
SB44994
Hexanoic acid,2-ethyl-, tridecyl ester
NCGC00091324-01
NCGC00091324-02
NCGC00091324-03
NCGC00253985-01
NCGC00258957-01
SMR001252268
E0120
2-Ethylhexanoic Acid
2-Ethylcaproic Acid
Isooctanoic Acid
Octanoic Acid, 2-ethyl-
2-ethylhexoic acid
Ethylhexoic Acid
FT-0612273
FT-0654390
EN300-20410
Q209384
W-109079
F0001-0703
Z104478072
18FEB650-7573-4EA0-B0CD-9D8BED766547
2-Ethylhexanoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

ETHYLHEXYL ACRYLATE, N° CAS : 103-11-7, Nom INCI : ETHYLHEXYL ACRYLATE. N° EINECS/ELINCS : 203-080-7. Ses fonctions (INCI) : Agent fixant : Permet la cohésion de différents ingrédients cosmétiques. Noms français : 2-ETHYLHEXYL-2-PROPENOATE 2-PROPENOIC ACID, 2-ETHYLHEXYL ESTER Acrylate d'éthyl-2 hexyle PROPENOATE-2 D'ETHYL-2 HEXYLE Noms anglais : 2-Ethylhexyl acrylate ACRYLIC ACID 2-ETHYLHEXYL ESTER ACRYLIC ACID, 2-ETHYLHEXYL ESTER ETHYLHEXYL-2 ACRYLATE Utilisation et sources d'émission Fabrication de polymères

ETHYLHEXYL BENZOATE, N° CAS : 5444-75-7. Nom INCI : ETHYLHEXYL BENZOATE. Nom chimique : 2-Ethylhexyl benzoate. N° EINECS/ELINCS : 226-641-8. Ses fonctions (INCI): Emollient : Adoucit et assouplit la peau. Agent d'entretien de la peau : Maintient la peau en bon état. Solvant : Dissout d'autres substances. 226-641-8 [EINECS] 2-Ethylhexyl benzoate 2-Ethylhexyl-benzoat [German] 4Y2&1OVR [WLN] 5444-75-7 [RN] Benzoate de 2-éthylhexyle [French] Benzoic acid, 2-ethylhexyl ester [ACD/Index Name] MFCD00072620 [MDL number] [5444-75-7] 2-Ethylhexylbenzoate benzoic acid 2-ethyl-hexyl ester BENZOICACID2-ETHYLHEXYLESTER Ethylhexyl benzoate PI-46931 Velate 368

ETHYLHEXYL COCOATE, N° CAS : 92044-87-6. Nom INCI : ETHYLHEXYL COCOATE. N° EINECS/ELINCS : 295-366-3. Ses fonctions (INCI) : Emollient : Adoucit et assouplit la peau

ETHYLHEXYL DIMETHYL PABA. N° CAS : 21245-02-3. Nom INCI : ETHYLHEXYL DIMETHYL PABA, Nom chimique : 2-Ethylhexyl 4-(dimethylamino)benzoate. N° EINECS/ELINCS : 244-289-3, Classification : Filtre UV Chimique, Règlementé. La concentration maximale autorisée en cosmétique est la suivante : 8 %.. Ses fonctions (INCI) : Absorbant UV : Protège le produit cosmétique contre les effets de la lumière UV. Filtre UV : Permet de filtrer certains rayons UV afin de protéger la peau ou les cheveux des effets nocifs de ces rayons.Noms français : OCTYL DIMETHYL PABA Noms anglais : 2-ETHYLHEXYL P-DIMETHYLAMINOBENZOATE; BENZOIC ACID, 4-(DIMETHYLAMINO)-, 2-ETHYLHEXYL ESTER