Carboxymethylcellulose (CMC), also known as cellulose gum, is a water-soluble polymer derived from cellulose, which is a natural polysaccharide found in the cell walls of plants.
Cellulose gum (carboxymethylcellulose) is composed of repeating glucose units linked together by β(1→4) glycosidic bonds.
CAS Number: 9004-32-4
EC Number: 618-378-6
Synonyms: Cellulose gum, Sodium CMC, Carboxymethyl cellulose, CMC, Cellulose carboxymethyl ether, Sodium cellulose glycolate, Sodium salt of carboxymethylcellulose, Cellulose carboxymethylate, Sodium carboxymethyl cellulose, Carboxymethylated cellulose, Cellulose carboxymethylether, Carboxymethyl ether of cellulose, Sodium carboxymethylcellulose ether, Carboxymethylated cellulose gum, Cellulose carboxymethylate sodium salt, Sodium salt of carboxymethyl cellulose ether, Carboxymethylcellulose sodium, Carboxymethylcellulose sodium salt, Sodium carboxymethyl cellulose gum, Sodium salt of carboxymethylcellulose gum, Carboxymethylcellulose ether sodium salt, Carboxymethyl cellulose ether sodium salt, Sodium carboxymethylcellulose gum, Carboxymethyl cellulose gum sodium salt, Carboxymethyl cellulose sodium salt, Sodium carboxymethyl cellulose ether, Sodium salt of carboxymethyl cellulose gum, Sodium salt of carboxymethylated cellulose, Sodium carboxymethylcellulose carboxymethylate, Carboxymethylated cellulose sodium salt, Sodium cellulose carboxymethylate, Carboxymethyl cellulose sodium, Sodium cellulose carboxymethylether, Sodium salt of carboxymethyl cellulose carboxymethylate, Sodium salt of carboxymethylated cellulose gum, Sodium salt of carboxymethylated cellulose ether, Sodium carboxymethylcellulose carboxymethylate, Sodium carboxymethyl cellulose sodium, Sodium carboxymethyl cellulose sodium salt, Sodium carboxymethyl cellulose carboxymethylether, Sodium cellulose carboxymethyl ether, Sodium salt of carboxymethyl cellulose sodium, Sodium salt of carboxymethyl cellulose sodium salt
APPLICATIONS
Cellulose gum (carboxymethylcellulose) is extensively used in the cosmetics industry to improve the texture and stability of lotions and creams.
Cellulose gum (carboxymethylcellulose) is a key ingredient in personal care products such as toothpaste and hair care items.
In industrial applications, CMC is utilized in papermaking as a coating additive and in textile printing pastes as a thickener.
Cellulose gum (carboxymethylcellulose)'s water-retention properties make it valuable in agricultural formulations for soil stabilization.
Cellulose gum (carboxymethylcellulose) is biodegradable and environmentally friendly, making it a preferred choice in many applications.
Cellulose gum (carboxymethylcellulose) can form gels at high concentrations or in the presence of multivalent ions.
Cellulose gum (carboxymethylcellulose) exhibits pseudoplastic behavior, meaning its viscosity decreases with increasing shear rate.
Cellulose gum (carboxymethylcellulose) is stable over a wide pH range, making it suitable for a variety of formulations.
The degree of substitution (DS) determines its solubility and rheological properties.
Cellulose gum (carboxymethylcellulose) undergoes rigorous quality control to ensure purity and consistency in manufacturing processes.
Cellulose gum (carboxymethylcellulose) is compatible with other additives and ingredients, allowing for versatile formulations.
Cellulose gum (carboxymethylcellulose) is generally recognized as safe (GRAS) for use in food and pharmaceutical products.
Its rheological properties can be adjusted to achieve desired flow characteristics in products.
Cellulose gum (carboxymethylcellulose) is soluble in cold water, facilitating its incorporation into formulations.
Cellulose gum (carboxymethylcellulose) has excellent film-forming properties, useful in coatings and packaging applications.
Cellulose gum (carboxymethylcellulose)'s versatility and stability make it a valuable additive in numerous industries.
Cellulose gum (carboxymethylcellulose) plays a crucial role in enhancing the quality, performance, and stability of various products.
Cellulose gum (carboxymethylcellulose) is widely used as a thickening agent in food products such as sauces, dressings, and soups.
Cellulose gum (carboxymethylcellulose) enhances the viscosity and texture of dairy products like ice cream and yogurt, preventing ice crystal formation and improving mouthfeel.
In baked goods, CMC helps to retain moisture and improve dough handling properties.
Cellulose gum (carboxymethylcellulose) is utilized in pharmaceutical formulations as a binder and disintegrant in tablets and capsules.
Cellulose gum (carboxymethylcellulose) controls the release of active ingredients in oral medications, ensuring proper dosage.
Cellulose gum (carboxymethylcellulose) is added to personal care products such as toothpaste and shampoo to provide viscosity and improve product performance.
In cosmetics, it acts as a thickening agent and stabilizer in creams, lotions, and gels.
Cellulose gum (carboxymethylcellulose) is employed in industrial applications such as papermaking, where it improves paper strength and printability.
Cellulose gum (carboxymethylcellulose) is used in textile printing pastes to improve color penetration and definition.
Cellulose gum (carboxymethylcellulose) serves as a suspension agent in ceramic glazes, preventing settling and ensuring uniform coverage.
Cellulose gum (carboxymethylcellulose) is added to detergents and cleaning products to enhance viscosity and stabilize formulations.
Cellulose gum (carboxymethylcellulose) is utilized in oil drilling fluids to control viscosity and fluid loss, improving drilling efficiency.
Cellulose gum (carboxymethylcellulose) acts as a binder in construction materials such as mortar and grout, improving workability and adhesion.
In the textile industry, CMC is applied as a sizing agent to increase fabric strength and reduce fiber breakage.
Cellulose gum (carboxymethylcellulose) is added to latex paints as a thickener and stabilizer, improving paint flow and leveling.
Cellulose gum (carboxymethylcellulose) is used in the production of adhesives and sealants to provide viscosity and improve bonding strength.
Cellulose gum (carboxymethylcellulose) is employed in agriculture as a suspension agent for pesticides and fertilizers, improving spray coverage.
Cellulose gum (carboxymethylcellulose) enhances the dispersion of active ingredients and prevents settling in spray solutions.
Cellulose gum (carboxymethylcellulose) is used in pet care products such as shampoos and grooming aids for its thickening and emulsifying properties.
Cellulose gum (carboxymethylcellulose) is added to ceramic membranes for water filtration applications, improving separation efficiency.
Cellulose gum (carboxymethylcellulose) is utilized in the manufacture of biodegradable films and coatings for packaging purposes.
In the oilfield industry, it is used in hydraulic fracturing fluids to improve fluid loss control.
Cellulose gum (carboxymethylcellulose) is added to artificial tears and eye drops to improve ocular surface hydration and lubrication.
Cellulose gum (carboxymethylcellulose) finds applications in the production of battery electrolytes to enhance viscosity and conductivity.
Cellulose gum (carboxymethylcellulose) is a versatile polymer with diverse applications across various industries, contributing to product performance and functionality.
Cellulose gum (carboxymethylcellulose) is used in the manufacture of ceramic tiles to improve adhesion and reduce cracking during drying.
Cellulose gum (carboxymethylcellulose) serves as a binder and thickener in pet foods, improving texture and palatability.
In battery electrolytes, CMC enhances viscosity and conductivity, contributing to battery performance.
Cellulose gum (carboxymethylcellulose) is employed in water-based paints and coatings as a rheology modifier, controlling flow and leveling.
Cellulose gum (carboxymethylcellulose) is added to petrochemical products as a thickener and suspending agent to improve stability.
Cellulose gum (carboxymethylcellulose) is used in the production of detergents and cleaning agents to provide thickening and foam stabilization.
Cellulose gum (carboxymethylcellulose) is employed in concrete mixes to improve slump retention and reduce water migration.
Cellulose gum (carboxymethylcellulose) serves as a sizing agent in textile dyeing, aiding in the even application of color.
In the construction industry, it is added to mortar and grout to improve workability and adhesion.
Cellulose gum (carboxymethylcellulose) is utilized in personal lubricants to enhance viscosity and lubricity.
Cellulose gum (carboxymethylcellulose) finds applications in the formulation of dietary supplements as a thickener and stabilizer.
Cellulose gum (carboxymethylcellulose) is added to latex paints as a thickener and stabilizer, improving paint performance.
In the textile industry, it is used in fabric finishing to reduce fiber abrasion and improve handle.
Cellulose gum (carboxymethylcellulose) serves as a suspension agent in ceramic membranes for water filtration, enhancing separation efficiency.
Cellulose gum (carboxymethylcellulose) is utilized in the production of biodegradable films and coatings for packaging applications.
Cellulose gum (carboxymethylcellulose) is added to hydraulic fracturing fluids in the oilfield industry to improve fluid loss control.
In the pharmaceutical sector, it is used in wound dressings and bandages for its absorbent properties.
Cellulose gum (carboxymethylcellulose) is employed in the manufacture of biocompatible medical implants and drug delivery systems.
Cellulose gum (carboxymethylcellulose) is added to drilling muds in oil drilling operations to control viscosity and fluid loss.
Cellulose gum (carboxymethylcellulose) is used in the production of artificial tears and eye drops to improve ocular surface hydration.
In the agricultural industry, it is utilized in crop protection products to improve spray coverage.
Cellulose gum (carboxymethylcellulose) is added to ceramic glazes to prevent settling of particles and ensure uniform coverage.
Cellulose gum (carboxymethylcellulose) finds applications in the formulation of dietary fiber supplements for gastrointestinal health.
Cellulose gum (carboxymethylcellulose) is employed in the manufacture of specialty papers such as cigarette filters and filter papers.
Cellulose gum (carboxymethylcellulose) offers a wide range of applications across industries, contributing to product quality, performance, and functionality.
DESCRIPTION
Carboxymethylcellulose (CMC), also known as cellulose gum, is a water-soluble polymer derived from cellulose, which is a natural polysaccharide found in the cell walls of plants.
Cellulose gum (carboxymethylcellulose) is composed of repeating glucose units linked together by β(1→4) glycosidic bonds.
Cellulose gum (carboxymethylcellulose) is produced through a chemical modification process known as carboxymethylation, in which hydroxyl groups (-OH) on the cellulose molecule are partially replaced by carboxymethyl groups (-CH2COONa).
This substitution reaction is typically carried out using sodium hydroxide (NaOH) and chloroacetic acid (ClCH2COOH) or its sodium salt (NaClCH2COO).
The introduction of carboxymethyl groups imparts water solubility and increased functionality to cellulose, making CMC a versatile polymer with a wide range of applications.
Cellulose gum (carboxymethylcellulose) is commonly used as a thickening agent, stabilizer, and emulsifier in various industries, including food, pharmaceuticals, cosmetics, and manufacturing.
Cellulose gum (carboxymethylcellulose) is typically supplied as a white to off-white powder or granules and is soluble in water, forming clear to slightly opaque solutions.
Cellulose gum (carboxymethylcellulose) exhibits pseudoplastic behavior, meaning its viscosity decreases with increasing shear rate.
Cellulose gum (carboxymethylcellulose) is stable over a wide pH range and has excellent film-forming properties.
Due to its biocompatibility, biodegradability, and non-toxic nature, carboxymethylcellulose is considered safe for use in food, pharmaceutical, and personal care products.
Cellulose gum (carboxymethylcellulose) undergoes rigorous quality control to ensure purity and consistency in manufacturing processes.
Carboxymethylcellulose, often referred to as CMC, is a versatile water-soluble polymer.
Derived from cellulose, Cellulose gum (carboxymethylcellulose) is a natural polysaccharide found in plant cell walls.
Cellulose gum (carboxymethylcellulose) is odorless and tasteless.
When dissolved in water, Cellulose gum (carboxymethylcellulose) forms clear to slightly opaque solutions.
Cellulose gum (carboxymethylcellulose) is known for its ability to thicken, stabilize, and emulsify a wide range of products.
Cellulose gum (carboxymethylcellulose) is commonly used in food as a thickening agent and stabilizer in products like sauces and dressings.
In pharmaceuticals, Cellulose gum (carboxymethylcellulose) serves as a binder and disintegrant in tablet formulations.
Cellulose gum (carboxymethylcellulose) is also found in ophthalmic solutions and topical creams due to its mucoadhesive properties.
PROPERTIES
Physical Properties:
Appearance: Typically a white to off-white powder or granules.
Odor: Odorless.
Taste: Tasteless.
Solubility: Soluble in water, forming clear to slightly opaque solutions.
pH: Typically ranges from 6.0 to 8.5 in a 1% aqueous solution.
Density: Varies depending on the grade and degree of substitution, typically around 0.5 to 0.7 g/cm³.
Molecular Weight: Varies depending on the degree of polymerization and substitution.
Particle Size: Varies depending on the grade and manufacturer, typically ranging from fine powder to granules.
Hygroscopicity: Absorbs moisture from the air, but does not dissolve in it.
Stability: Stable under normal storage conditions, but may degrade at high temperatures or extreme pH levels.
Chemical Properties:
Chemical Formula: (C6H10O5)n - [C6H7O2(OH)2CH2COONa]m
Molecular Structure: Linear polymer consisting of repeating glucose units with carboxymethyl groups attached.
Degree of Substitution (DS): The average number of carboxymethyl groups per glucose unit in the cellulose chain, typically ranging from 0.2 to 1.5.
Ionic Character: Anionic polymer due to the presence of carboxymethyl groups, which dissociate in water to form negatively charged carboxylate ions.
Degree of Polymerization (DP): The average number of glucose units in the cellulose chain, which can vary depending on the source and manufacturing process.
Hydrophilicity: Highly hydrophilic due to the presence of numerous hydroxyl groups, making it readily soluble in water.
Rheological Properties: Exhibits pseudoplastic behavior, meaning its viscosity decreases with increasing shear rate.
Gel Formation: Can form gels at high concentrations or in the presence of multivalent ions such as calcium.
pH Sensitivity: Stable over a wide pH range, but may undergo degradation at extreme pH values.
Thermal Properties: Decomposes at high temperatures, typically above 200°C, releasing carbon dioxide and water vapor.
Biodegradability: Biodegradable under certain conditions, with degradation rates depending on environmental factors such as temperature, moisture, and microbial activity.
FIRST AID
Inhalation:
Move the affected person to fresh air if they are experiencing respiratory discomfort.
If breathing is difficult, provide oxygen and seek medical attention immediately.
If the person is not breathing, perform artificial respiration and seek emergency medical assistance.
Skin Contact:
Remove contaminated clothing and rinse the affected area with plenty of water.
Wash skin thoroughly with soap and water.
If irritation persists or if skin becomes damaged, seek medical attention.
Contaminated clothing should be removed and washed before reuse.
Eye Contact:
Flush eyes with gently flowing water for at least 15 minutes, holding the eyelids open to ensure thorough rinsing.
Seek immediate medical attention, even if irritation or pain is mild.
Remove contact lenses if present and easy to do so, but do not delay irrigation to do this.
Ingestion:
Do not induce vomiting unless directed by medical personnel.
Rinse mouth with water and drink plenty of water to dilute the material.
Seek medical attention immediately, especially if a large amount of the substance has been ingested.
Notes to Physician:
Treat symptomatically and supportively.
In case of inhalation, administer oxygen and assist ventilation if necessary.
For eye contact, evaluate for corneal injury and treat accordingly.
If ingested, monitor for gastrointestinal symptoms and provide appropriate supportive care.
General Advice:
Ensure that affected individuals are removed from exposure and provided with appropriate medical attention.
Do not administer anything orally to an unconscious person.
In case of fire or explosion, follow appropriate firefighting procedures and evacuation protocols.
Personal Protective Equipment (PPE):
When handling CMC, wear suitable protective clothing, gloves, and eye/face protection to minimize skin and eye contact.
Use respiratory protection if ventilation is inadequate or if handling the substance in dusty conditions.
Emergency Procedures:
In case of a spill or release, contain the material and prevent further spread.
Clean up spills promptly using appropriate methods and equipment to minimize exposure.
Dispose of contaminated materials in accordance with local regulations and guidelines.
HANDLING AND STORAGE
Handling:
Personal Protective Equipment (PPE):
Wear appropriate protective clothing, including gloves, safety goggles, and a lab coat or protective clothing, to prevent skin contact and eye irritation.
Use respiratory protection if handling Cellulose gum (carboxymethylcellulose) in dusty conditions or if ventilation is inadequate.
Handling Precautions:
Avoid inhalation of dust or mist by handling Cellulose gum (carboxymethylcellulose) in well-ventilated areas.
Minimize skin contact by wearing gloves and other protective clothing.
Use dust control measures such as local exhaust ventilation or dust suppression techniques to reduce airborne dust levels.
Do not eat, drink, or smoke while handling Cellulose gum (carboxymethylcellulose).
Wash hands thoroughly with soap and water after handling Cellulose gum (carboxymethylcellulose) and before eating, drinking, or using the restroom.
Equipment Handling:
Use appropriate handling equipment such as scoops, shovels, or containers with lids to transfer Cellulose gum (carboxymethylcellulose) to prevent spills and minimize dust generation.
Ensure that handling equipment is clean and dry to prevent contamination of CMC.
Avoidance of Incompatible Materials:
Store Cellulose gum (carboxymethylcellulose) away from strong acids, bases, oxidizing agents, and incompatible materials to prevent reactions or degradation.
Storage:
Storage Conditions:
Store Cellulose gum (carboxymethylcellulose) in a cool, dry, well-ventilated area away from direct sunlight and heat sources.
Maintain storage temperatures within the recommended range specified by the manufacturer to prevent degradation.
Keep containers tightly closed when not in use to prevent contamination and moisture absorption.
Container Compatibility:
Use containers made of compatible materials such as polyethylene, polypropylene, or glass to store Cellulose gum (carboxymethylcellulose).
Ensure that containers are clean, dry, and free from any residues to prevent contamination of Cellulose gum (carboxymethylcellulose).
Separation from Incompatible Substances:
Store Cellulose gum (carboxymethylcellulose) away from incompatible materials such as strong acids, bases, oxidizing agents, and reactive chemicals to prevent reactions or contamination.
Segregation Requirements:
Segregate Cellulose gum (carboxymethylcellulose) from food, feed, and pharmaceuticals to prevent accidental contamination.
Handling of Large Quantities:
If handling large quantities of Cellulose gum (carboxymethylcellulose), use appropriate storage facilities such as warehouses or storage rooms equipped with adequate ventilation and temperature control.
Storage Duration:
Follow the manufacturer's recommendations for shelf life and storage duration of Cellulose gum (carboxymethylcellulose).
Rotate stock regularly to ensure that older material is used first and to minimize the risk of degradation or spoilage.
Security Measures:
Store Cellulose gum (carboxymethylcellulose) in a secure area to prevent unauthorized access or tampering.
Labeling:
Clearly label containers of Cellulose gum (carboxymethylcellulose) with the product name, manufacturer information, date of receipt, and any relevant hazard information.
Emergency Preparedness:
Have appropriate spill control and containment measures in place in case of accidental spills or releases.
Train personnel on proper handling and emergency response procedures for Cellulose gum (carboxymethylcellulose).